WorldWideScience

Sample records for safety monitor rsm

  1. RsmV a small non-coding regulatory RNA in Pseudomonas aeruginosa that sequesters RsmA and RsmF from target mRNAs.

    Science.gov (United States)

    Janssen, Kayley H; Diaz, Manisha R; Gode, Cindy J; Wolfgang, Matthew C; Yahr, Timothy L

    2018-06-04

    The Gram-negative opportunistic pathogen Pseudomonas aeruginosa has distinct genetic programs that favor either acute or chronic virulence gene expression. Acute virulence is associated with twitching and swimming motility, expression of a type III secretion system (T3SS), and the absence of alginate, Psl, or Pel polysaccharide production. Traits associated with chronic infection include growth as a biofilm, reduced motility, and expression of a type VI secretion system (T6SS). The Rsm post-transcriptional regulatory system plays important roles in the inverse control of phenotypes associated with acute and chronic virulence. RsmA and RsmF are RNA-binding proteins that interact with target mRNAs to control gene expression at the post-transcriptional level. Previous work found that RsmA activity is controlled by at least three small, non-coding regulatory RNAs (RsmW, RsmY, and RsmZ). In this study, we took an in-silico approach to identify additional sRNAs that might function in the sequestration of RsmA and/or RsmF and identified RsmV, a 192 nt transcript with four predicted RsmA/RsmF consensus binding sites. RsmV is capable of sequestering RsmA and RsmF in vivo to activate translation of tssA1 , a component of the T6SS, and to inhibit T3SS gene expression. Each of the predicted RsmA/RsmF consensus binding sites contribute to RsmV activity. Electrophoretic mobility shifts assays show that RsmF binds RsmV with >10-fold higher affinity than RsmY and RsmZ. Gene expression studies revealed that the temporal expression pattern of RsmV differs from RsmW, RsmY, and RsmZ. These findings suggest that each sRNA may play distinct roles in controlling RsmA and RsmF activity. IMPORTANCE The CsrA/RsmA family of RNA-binding proteins play important roles in post-transcriptional control of gene expression. The activity of CsrA/RsmA proteins is controlled by small non-coding RNAs that function as decoys to sequester CsrA/RsmA from target mRNAs. Pseudomonas aeruginosa has two Csr

  2. Radioactive scrap metal (RSM) inventory ampersand tracking system and prototype RSM field survey

    International Nuclear Information System (INIS)

    Thomas, T.R.

    1994-09-01

    Based on very preliminary information, it has been estimated that the radioactive scrap metal (RSM) inventories at DOE facilities amount to about 1.5 million tons and a much larger amount will be generated from decontamination and decommissioning of surplus DOE facilities. To implement a national DOE program for beneficial reuse of RSM, it will be necessary to known the location and characteristics of RSM inventories that are available and will be generated to match them with product demands. It is the intent of this task to provide a standardized methodology via a RSM database for recording, tracking, and reporting data on RSM inventories. A multiple relational database in dBASE IV was designed and a PC-based code was written in Clipper 5.0 syntax to expedite entry, editing, querying, and reporting of RSM survey data. The PC based-code, the multiple relational database files, and other external files used by the code to generate reports and queries constitute a customized software application called the RSM Inventory ampersand Tracking System (RSM I ampersand TS). A prototype RSM field survey was conducted at the Nevada Test Site (NTS) to demonstrate the field use of the RSM I ampersand TS and logistics of conducting the survey. During the demonstration, about 50 tons of RSM were sized, characterized, sorted, and packaged in transport containers

  3. RSM Outlook Autumn 2005 : Branding

    NARCIS (Netherlands)

    G. Kemp (Gail); R. Morris (Rebecca)

    2005-01-01

    markdownabstract#### Contents The inaugural issue of RSM Outlook from autumn 2005 includes the opening of the new T-building, and how RSM celebrated its 35th birthday with a wine-tasting session. There are also articles on Professor Cees van Riel and reputation management, the re-branding of the

  4. Identification of the RsmG methyltransferase target as 16S rRNA nucleotide G527 and characterization of Bacillus subtilis rsmG mutants

    DEFF Research Database (Denmark)

    Nishimura, Kenji; Johansen, Shanna K; Inaoka, Takashi

    2007-01-01

    The methyltransferase RsmG methylates the N7 position of nucleotide G535 in 16S rRNA of Bacillus subtilis (corresponding to G527 in Escherichia coli). Disruption of rsmG resulted in low-level resistance to streptomycin. A growth competition assay revealed that there are no differences in fitness...... between the rsmG mutant and parent strains under the various culture conditions examined. B. subtilis rsmG mutants emerged spontaneously at a relatively high frequency, 10(-6). Importantly, in the rsmG mutant background, high-level-streptomycin-resistant rpsL (encoding ribosomal protein S12) mutants...

  5. Climate Downscaling over Nordeste, Brazil, Using the NCEP RSM97.

    Science.gov (United States)

    Sun, Liqiang; Ferran Moncunill, David; Li, Huilan; Divino Moura, Antonio; de Assis de Souza Filho, Francisco

    2005-02-01

    The NCEP Regional Spectral Model (RSM), with horizontal resolution of 60 km, was used to downscale the ECHAM4.5 AGCM (T42) simulations forced with observed SSTs over northeast Brazil. An ensemble of 10 runs for the period January-June 1971-2000 was used in this study. The RSM can resolve the spatial patterns of observed seasonal precipitation and capture the interannual variability of observed seasonal precipitation as well. The AGCM bias in displacement of the Atlantic ITCZ is partially corrected in the RSM. The RSM probability distribution function of seasonal precipitation anomalies is in better agreement with observations than that of the driving AGCM. Good potential prediction skills are demonstrated by the RSM in predicting the interannual variability of regional seasonal precipitation. The RSM can also capture the interannual variability of observed precipitation at intraseasonal time scales, such as precipitation intensity distribution and dry spells. A drought index and a flooding index were adopted to indicate the severity of drought and flooding conditions, and their interannual variability was reproduced by the RSM. The overall RSM performance in the downscaled climate of the ECHAM4.5 AGCM is satisfactory over Nordeste. The primary deficiency is a systematic dry bias for precipitation simulation.

  6. Stainless Steel RSM Beneficial Reuse technical feasibility to business reality

    International Nuclear Information System (INIS)

    Boettinger, W.L.; Mishra, G.

    1997-08-01

    The Stainless Steel Beneficial Reuse Program began in 1994 as a demonstration funded by the DOE Office of Science and Technology. The purpose was to assess the practicality of stainless steel radioactive scrap metal (RSM) recycle. Technical feasibility has been demonstrated through the production of a number of products made from recycled RSM. A solid business foundation is yet to be achieved. However, a business environment is beginning to develop as multiple markets and applications for RSM are surfacing around the Complex. The criteria for a successful business reality includes: - affordable programs, - a continuing production base from which to expand, - real products needs, -adequate RSM supply, and - a multi-year program This program currently sponsored by SRS and DOE-ORO to fabricate Defense Waste Processing Facility (DWPF) canisters from RSM provides an activity that satisfies these criteria. The program status is discussed. A comparison of the cost of DWPF canisters fabricated from recycled RSM and virgin metal is presented. The comparison is a function of several factors: disposal costs, the fabrication cost of virgin metal canisters, the fabrication cost of recycled RSM canisters, free release decontamination costs, and the cost to accumulate the RSM. These variables are analyzed and the relationship established to show the break-even point for various values of each parameter

  7. Safety system status monitoring

    International Nuclear Information System (INIS)

    Lewis, J.R.; Morgenstern, M.H.; Rideout, T.H.; Cowley, P.J.

    1984-03-01

    The Pacific Northwest Laboratory has studied the safety aspects of monitoring the preoperational status of safety systems in nuclear power plants. The goals of the study were to assess for the NRC the effectiveness of current monitoring systems and procedures, to develop near-term guidelines for reducing human errors associated with monitoring safety system status, and to recommend a regulatory position on this issue. A review of safety system status monitoring practices indicated that current systems and procedures do not adequately aid control room operators in monitoring safety system status. This is true even of some systems and procedures installed to meet existing regulatory guidelines (Regulatory Guide 1.47). In consequence, this report suggests acceptance criteria for meeting the functional requirements of an adequate system for monitoring safety system status. Also suggested are near-term guidelines that could reduce the likelihood of human errors in specific, high-priority status monitoring tasks. It is recommended that (1) Regulatory Guide 1.47 be revised to address these acceptance criteria, and (2) the revised Regulatory Guide 1.47 be applied to all plants, including those built since the issuance of the original Regulatory Guide

  8. Safety system status monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, J.R.; Morgenstern, M.H.; Rideout, T.H.; Cowley, P.J.

    1984-03-01

    The Pacific Northwest Laboratory has studied the safety aspects of monitoring the preoperational status of safety systems in nuclear power plants. The goals of the study were to assess for the NRC the effectiveness of current monitoring systems and procedures, to develop near-term guidelines for reducing human errors associated with monitoring safety system status, and to recommend a regulatory position on this issue. A review of safety system status monitoring practices indicated that current systems and procedures do not adequately aid control room operators in monitoring safety system status. This is true even of some systems and procedures installed to meet existing regulatory guidelines (Regulatory Guide 1.47). In consequence, this report suggests acceptance criteria for meeting the functional requirements of an adequate system for monitoring safety system status. Also suggested are near-term guidelines that could reduce the likelihood of human errors in specific, high-priority status monitoring tasks. It is recommended that (1) Regulatory Guide 1.47 be revised to address these acceptance criteria, and (2) the revised Regulatory Guide 1.47 be applied to all plants, including those built since the issuance of the original Regulatory Guide.

  9. RSM 1.0 - A RESUPPLY SCHEDULER USING INTEGER OPTIMIZATION

    Science.gov (United States)

    Viterna, L. A.

    1994-01-01

    RSM, Resupply Scheduling Modeler, is a fully menu-driven program that uses integer programming techniques to determine an optimum schedule for replacing components on or before the end of a fixed replacement period. Although written to analyze the electrical power system on the Space Station Freedom, RSM is quite general and can be used to model the resupply of almost any system subject to user-defined resource constraints. RSM is based on a specific form of the general linear programming problem in which all variables in the objective function and all variables in the constraints are integers. While more computationally intensive, integer programming was required for accuracy when modeling systems with small quantities of components. Input values for component life cane be real numbers, RSM converts them to integers by dividing the lifetime by the period duration, then reducing the result to the next lowest integer. For each component, there is a set of constraints that insure that it is replaced before its lifetime expires. RSM includes user-defined constraints such as transportation mass and volume limits, as well as component life, available repair crew time and assembly sequences. A weighting factor allows the program to minimize factors such as cost. The program then performs an iterative analysis, which is displayed during the processing. A message gives the first period in which resources are being exceeded on each iteration. If the scheduling problem is unfeasible, the final message will also indicate the first period in which resources were exceeded. RSM is written in APL2 for IBM PC series computers and compatibles. A stand-alone executable version of RSM is provided; however, this is a "packed" version of RSM which can only utilize the memory within the 640K DOS limit. This executable requires at least 640K of memory and DOS 3.1 or higher. Source code for an APL2/PC workspace version is also provided. This version of RSM can make full use of any

  10. RSM Outlook Winter 2013: Growing Tomorrow's Entrepreneurs

    OpenAIRE

    Whittern, Justine; Schreiner, Dorine

    2013-01-01

    markdownabstract#### Innovation and the path to value (Russell Gilbert) At the RSM Leadership Summit in October, Frans van Houten, CEO of Royal Philips (pictured), gave a uniquely insightful presentation about the benefits of organisational transformation, innovation, and the importance of keeping abreast of technological and societal changes. In an exclusive interview, Mr Van Houten discusses these issues with Russell Gilbert, Managing Editor of RSM Outlook. #### Ready for lift off!! (Bennet...

  11. RSM Outlook Spring 2007 : Green Technology: The New IT

    NARCIS (Netherlands)

    R. Morris (Rebecca)

    2007-01-01

    markdownabstract#### Sustaining change (Rebecca Morris) An interview with RSM alumnus and Royal DSM Managing Board member Feike Sijbesma. #### Why celebrity sells: The brain mechanisms of persuasion (Vittorio Busato & Rebecca Morris) Marketing researchers at RSM are combining the latest

  12. Genome-wide mapping of the RNA targets of the Pseudomonas aeruginosa riboregulatory protein RsmN.

    Science.gov (United States)

    Romero, Manuel; Silistre, Hazel; Lovelock, Laura; Wright, Victoria J; Chan, Kok-Gan; Hong, Kar-Wai; Williams, Paul; Cámara, Miguel; Heeb, Stephan

    2018-04-30

    Pseudomonads typically carry multiple non-identical alleles of the post-transcriptional regulator rsmA. In Pseudomonas aeruginosa, RsmN is notable in that its structural rearrangement confers distinct and overlapping functions with RsmA. However, little is known about the specificities of RsmN for its target RNAs and overall impact on the biology of this pathogen. We purified and mapped 503 transcripts directly bound by RsmN in P. aeruginosa. About 200 of the mRNAs identified encode proteins of demonstrated function including some determining acute and chronic virulence traits. For example, RsmN reduces biofilm development both directly and indirectly via multiple pathways, involving control of Pel exopolysaccharide biosynthesis and c-di-GMP levels. The RsmN targets identified are also shared with RsmA, although deletion of rsmN generally results in less pronounced phenotypes than those observed for ΔrsmA or ΔrsmArsmNind mutants, probably as a consequence of different binding affinities. Targets newly identified for the Rsm system include the small non-coding RNA CrcZ involved in carbon catabolite repression, for which differential binding of RsmN and RsmA to specific CrcZ regions is demonstrated. The results presented here provide new insights into the intricacy of riboregulatory networks involving multiple but distinct RsmA homologues.

  13. Global regulators ExpA (GacA) and KdgR modulate extracellular enzyme gene expression through the RsmA-rsmB system in Erwinia carotovora subsp. carotovora.

    Science.gov (United States)

    Hyytiäinen, H; Montesano, M; Palva, E T

    2001-08-01

    The production of the main virulence determinants, the extracellular plant cell wall-degrading enzymes, and hence virulence of Erwinia carotovora subsp. carotovora is controlled by a complex regulatory network. One of the global regulators, the response regulator ExpA, a GacA homolog, is required for transcriptional activation of the extracellular enzyme genes of this soft-rot pathogen. To elucidate the mechanism of ExpA control as well as interactions with other regulatory systems, we isolated second-site transposon mutants that would suppress the enzyme-negative phenotype of an expA (gacA) mutant. Inactivation of kdgR resulted in partial restoration of extracellular enzyme production and virulence to the expA mutant, suggesting an interaction between the two regulatory pathways. This interaction was mediated by the RsmA-rsmB system. Northern analysis was used to show that the regulatory rsmB RNA was under positive control of ExpA. Conversely, the expression of rsmA encoding a global repressor was under negative control of ExpA and positive control of KdgR. This study indicates a central role for the RsmA-rsmB regulatory system during pathogenesis, integrating signals from the ExpA (GacA) and KdgR global regulators of extracellular enzyme production in E. carotovora subsp. carotovora.

  14. CRISPR-Cas gene-editing reveals RsmA and RsmC act through FlhDC to repress the SdhE flavinylation factor and control motility and prodigiosin production in Serratia.

    Science.gov (United States)

    Hampton, Hannah G; McNeil, Matthew B; Paterson, Thomas J; Ney, Blair; Williamson, Neil R; Easingwood, Richard A; Bostina, Mihnea; Salmond, George P C; Fineran, Peter C

    2016-06-01

    SdhE is required for the flavinylation and activation of succinate dehydrogenase and fumarate reductase (FRD). In addition, SdhE is conserved in proteobacteria (α, β and γ) and eukaryotes. Although the function of this recently characterized family of proteins has been determined, almost nothing is known about how their genes are regulated. Here, the RsmA (CsrA) and RsmC (HexY) post-transcriptional and post-translational regulators have been identified and shown to repress sdhEygfX expression in Serratia sp. ATCC 39006. Conversely, the flagella master regulator complex, FlhDC, activated sdhEygfX transcription. To investigate the hierarchy of control, we developed a novel approach that utilized endogenous CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR associated) genome-editing by a type I-F system to generate a chromosomal point mutation in flhC. Mutation of flhC alleviated the ability of RsmC to repress sdhEygfX expression, whereas RsmA acted in both an FlhDC-dependent and -independent manner to inhibit sdhEygfX. Mutation of rsmA or rsmC, or overexpression of FlhDC, led to increased prodigiosin, biosurfactant, swimming and swarming. Consistent with the modulation of sdhE by motility regulators, we have demonstrated that SdhE and FRD are required for maximal flagella-dependent swimming. Together, these results demonstrate that regulators of both metabolism and motility (RsmA, RsmC and FlhDC) control the transcription of the sdhEygfX operon.

  15. Regulation of host-pathogen interactions via the post-transcriptional Csr/Rsm system.

    Science.gov (United States)

    Kusmierek, Maria; Dersch, Petra

    2018-02-01

    A successful colonization of specific hosts requires a rapid and efficient adaptation of the virulence-relevant gene expression program by bacterial pathogens. An important element in this endeavor is the Csr/Rsm system. This multi-component, post-transcriptional control system forms a central hub within complex regulatory networks and coordinately adjusts virulence properties with metabolic and physiological attributes of the pathogen. A key function is elicited by the RNA-binding protein CsrA/RsmA. CsrA/RsmA interacts with numerous target mRNAs, many of which encode crucial virulence factors, and alters their translation, stability or elongation of transcription. Recent studies highlighted that important colonization factors, toxins, and bacterial secretion systems are under CsrA/RsmA control. CsrA/RsmA deficiency impairs host colonization and attenuates virulence, making this post-transcriptional regulator a suitable drug target. The CsrA/RsmA protein can be inactivated through sequestration by non-coding RNAs, or via binding to specific highly abundant mRNAs and interacting proteins. The wide range of interaction partners and RNA targets, as well as the overarching, interlinked genetic control circuits illustrate the complexity of this regulatory system in the different pathogens. Future work addressing spatio-temporal changes of Csr/Rsm-mediated control during the course of an infection will help us to understand how bacteria reprogram their expression profile to cope with continuous changes experienced in colonized niches. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. RSM Outlook Spring 2007: Green Technology: The New IT

    OpenAIRE

    Morris, Rebecca

    2007-01-01

    markdownabstract#### Sustaining change (Rebecca Morris) An interview with RSM alumnus and Royal DSM Managing Board member Feike Sijbesma. #### Why celebrity sells: The brain mechanisms of persuasion (Vittorio Busato & Rebecca Morris) Marketing researchers at RSM are combining the latest neuroimaging techniques to discover more about what goes on in the brains of consumers. For marketeers, this may help take the last remaining guesswork out of pricey advertising campaigns. #### Green technolog...

  17. Structural basis of the non-coding RNA RsmZ acting as a protein sponge.

    Science.gov (United States)

    Duss, Olivier; Michel, Erich; Yulikov, Maxim; Schubert, Mario; Jeschke, Gunnar; Allain, Frédéric H-T

    2014-05-29

    MicroRNA and protein sequestration by non-coding RNAs (ncRNAs) has recently generated much interest. In the bacterial Csr/Rsm system, which is considered to be the most general global post-transcriptional regulatory system responsible for bacterial virulence, ncRNAs such as CsrB or RsmZ activate translation initiation by sequestering homodimeric CsrA-type proteins from the ribosome-binding site of a subset of messenger RNAs. However, the mechanism of ncRNA-mediated protein sequestration is not understood at the molecular level. Here we show for Pseudomonas fluorescens that RsmE protein dimers assemble sequentially, specifically and cooperatively onto the ncRNA RsmZ within a narrow affinity range. This assembly yields two different native ribonucleoprotein structures. Using a powerful combination of nuclear magnetic resonance and electron paramagnetic resonance spectroscopy we elucidate these 70-kilodalton solution structures, thereby revealing the molecular mechanism of the sequestration process and how RsmE binding protects the ncRNA from RNase E degradation. Overall, our findings suggest that RsmZ is well-tuned to sequester, store and release RsmE and therefore can be viewed as an ideal protein 'sponge'.

  18. Safety monitoring in process and control

    International Nuclear Information System (INIS)

    Esparza, V. Jr.; Sebo, D.E.

    1984-01-01

    Safety Functions provide a method of ensuring the safe operation of any large-scale processing plant. Successful implementation of safety functions requires continuous monitoring of safety function values and trends. Because the volume of information handled by a plant operator occassionally can become overwhelming, attention may be diverted from the primary concern of maintaining plant safety. With this in mind EG and G, Idaho developed various methods and techniques for use in a computerized Safety Function Monitoring System and tested the application of these techniques using a simulated nuclear power plant, the Loss-of-Fluid Test Facility (LOFT) at the Idaho National Engineering Laboratory (INEL). This paper presents the methods used in the development of a Safety Function Monitoring System

  19. Hawaii Regional Sediment Management (RSM): Regional Sediment Budget for the West Maui Region

    Science.gov (United States)

    2016-06-01

    ER D C/ CH L TR -1 6- 5 Regional Sediment Management (RSM) Program Hawaii Regional Sediment Management (RSM): Regional Sediment Budget...acwc.sdp.sirsi.net/client/default. Regional Sediment Management (RSM) Program ERDC/CHL TR-16-5 June 2016 Hawaii Regional Sediment Management...distribution is unlimited. Prepared for U.S. Army Corps of Engineers Washington, DC 20314-1000 Under Project 454632, “ Hawaii Regional Sediment Management

  20. Molecular basis for the wide range of affinity found in Csr/Rsm protein-RNA recognition.

    Science.gov (United States)

    Duss, Olivier; Michel, Erich; Diarra dit Konté, Nana; Schubert, Mario; Allain, Frédéric H-T

    2014-04-01

    The carbon storage regulator/regulator of secondary metabolism (Csr/Rsm) type of small non-coding RNAs (sRNAs) is widespread throughout bacteria and acts by sequestering the global translation repressor protein CsrA/RsmE from the ribosome binding site of a subset of mRNAs. Although we have previously described the molecular basis of a high affinity RNA target bound to RsmE, it remains unknown how other lower affinity targets are recognized by the same protein. Here, we have determined the nuclear magnetic resonance solution structures of five separate GGA binding motifs of the sRNA RsmZ of Pseudomonas fluorescens in complex with RsmE. The structures explain how the variation of sequence and structural context of the GGA binding motifs modulate the binding affinity for RsmE by five orders of magnitude (∼10 nM to ∼3 mM, Kd). Furthermore, we see that conformational adaptation of protein side-chains and RNA enable recognition of different RNA sequences by the same protein contributing to binding affinity without conferring specificity. Overall, our findings illustrate how the variability in the Csr/Rsm protein-RNA recognition allows a fine-tuning of the competition between mRNAs and sRNAs for the CsrA/RsmE protein.

  1. Quorum sensing controls the synthesis of virulence factors by modulating rsmA gene expression in Erwinia carotovora subsp. carotovora.

    Science.gov (United States)

    Kõiv, V; Mäe, A

    2001-04-01

    The plant-pathogenic bacterium Erwinia carotovora subsp. carotovora (Ecc) causes disease mainly by means of a number of extracellular plant cell wall-degrading enzymes (PCWDEs), also referred to as virulence factors. The production of PCWDEs is coordinately activated by the diffusible signal molecule N-acyl-homoserine lactone (HSL) in a population density-dependent manner ("quorum sensing"). ExpI is the enzyme responsible for the synthesis of HSL. The Rsm system negatively regulates the production of PCWDEs. It includes three components: RsmA is an RNA-binding protein which promotes mRNA decay; rsmB is a unique regulator RNA, and RsmC regulates expression of rsmA positively and of rsmB negatively. We report here that in an expI knockout mutant of Ecc strain SCC3193, the levels of rsmA and rsmB RNA are remarkably enhanced in comparison to the wild-type strain, while the level of the rsmC transcript is not affected. The increase in transcription of rsmA in the expI strain represses production of PCWDEs, which in turn leads to the avirulent phenotype of this mutant. In the expI- mutant, addition of exogenous HSL caused repression of rsmA and rsmB transcription to the wild-type level, whereas the expression of rsmC was not affected. Taken together, these data suggest that HSL affects the expression of rsmA, and that this effect is not mediated by RsmC. This specific effect and the previous demonstration that HSL is required for PCWDE production in Ecc support the hypothesis that regulation by quorum sensing in Ecc, in contrast to most other systems already described, requires HSL to repress rsmA transcription, which in turn leads to the activation of PCWDE production. A model is presented that explains how HSL controls the production of PCWDEs by modulating the expression of rsmA.

  2. RSM Outlook Summer 2009 : Post-Crisis World: a change for the better?

    NARCIS (Netherlands)

    R. Gilbert (Russell); L. Sawahata (Lesa)

    2009-01-01

    markdownabstract#### Business and Academia: The Mutual Benefits of Collaboration (Lesa Sawahata) Business is at the heart – and in the DNA – of RSM. And through collaborative activities at every level, RSM researchers, alumni and students are impacting business. #### The New Face of

  3. Warpage optimization on a mobile phone case using response surface methodology (RSM)

    Science.gov (United States)

    Lee, X. N.; Fathullah, M.; Shayfull, Z.; Nasir, S. M.; Hazwan, M. H. M.; Shazzuan, S.

    2017-09-01

    Plastic injection moulding is a popular manufacturing method not only it is reliable, but also efficient and cost saving. It able to produce plastic part with detailed features and complex geometry. However, defects in injection moulding process degrades the quality and aesthetic of the injection moulded product. The most common defect occur in the process is warpage. Inappropriate process parameter setting of injection moulding machine is one of the reason that leads to the occurrence of warpage. The aims of this study were to improve the quality of injection moulded part by investigating the optimal parameters in minimizing warpage using Response Surface Methodology (RSM). Subsequent to this, the most significant parameter was identified and recommended parameters setting was compared with the optimized parameter setting using RSM. In this research, the mobile phone case was selected as case study. The mould temperature, melt temperature, packing pressure, packing time and cooling time were selected as variables whereas warpage in y-direction was selected as responses in this research. The simulation was carried out by using Autodesk Moldflow Insight 2012. In addition, the RSM was performed by using Design Expert 7.0. The warpage in y direction recommended by RSM were reduced by 70 %. RSM performed well in solving warpage issue.

  4. The Csr/Rsm system of Yersinia and related pathogens: a post-transcriptional strategy for managing virulence.

    Science.gov (United States)

    Heroven, Ann Kathrin; Böhme, Katja; Dersch, Petra

    2012-04-01

    This review emphasizes the function and regulation of the Csr regulatory system in the human enteropathogen Yersinia pseudotuberculosis and compares its features with the homologous Csr/Rsm systems of related pathogens. The Csr/Rsm systems of eubacteria form a complex regulatory network in which redundant non-translated Csr/Rsm-RNAs bind the RNA-binding protein CsrA/RsmA, thereby preventing its interaction with mRNA targets. The Csr system is controlled by the BarA/UvrY-type of two-component sensor-regulator systems. Apart from that, common or pathogen-specific regulators control the abundance of the Csr components. The coordinate control of virulence factors and infection-linked physiological traits by the Csr/Rsm systems helps the pathogens to adapt individually to rapidly changing conditions to which they are exposed during the different stages of an infection. As Csr/Rsm function is relevant for full virulence, it represents a target suitable for antimicrobial drug development.

  5. RSM Outlook Winter 2013 : Growing Tomorrow's Entrepreneurs

    NARCIS (Netherlands)

    J. Whittern (Justine); D. Schreiner (Dorine)

    2013-01-01

    markdownabstract#### Innovation and the path to value (Russell Gilbert) At the RSM Leadership Summit in October, Frans van Houten, CEO of Royal Philips (pictured), gave a uniquely insightful presentation about the benefits of organisational transformation, innovation, and the importance of

  6. CERN safety system monitoring - SSM

    International Nuclear Information System (INIS)

    Hakulinen, T.; Ninin, P.; Valentini, F.; Gonzalez, J.; Salatko-Petryszcze, C.

    2012-01-01

    CERN SSM (Safety System Monitoring) is a system for monitoring state-of-health of the various access and safety systems of the CERN site and accelerator infrastructure. The emphasis of SSM is on the needs of maintenance and system operation with the aim of providing an independent and reliable verification path of the basic operational parameters of each system. Included are all network-connected devices, such as PLCs (local purpose control unit), servers, panel displays, operator posts, etc. The basic monitoring engine of SSM is a freely available system-monitoring framework Zabbix, on top of which a simplified traffic-light-type web-interface has been built. The web-interface of SSM is designed to be ultra-light to facilitate access from hand-held devices over slow connections. The underlying Zabbix system offers history and notification mechanisms typical of advanced monitoring systems. (authors)

  7. Monitoring product safety in the postmarketing environment.

    Science.gov (United States)

    Sharrar, Robert G; Dieck, Gretchen S

    2013-10-01

    The safety profile of a medicinal product may change in the postmarketing environment. Safety issues not identified in clinical development may be seen and need to be evaluated. Methods of evaluating spontaneous adverse experience reports and identifying new safety risks include a review of individual reports, a review of a frequency distribution of a list of the adverse experiences, the development and analysis of a case series, and various ways of examining the database for signals of disproportionality, which may suggest a possible association. Regulatory agencies monitor product safety through a variety of mechanisms including signal detection of the adverse experience safety reports in databases and by requiring and monitoring risk management plans, periodic safety update reports and postauthorization safety studies. The United States Food and Drug Administration is working with public, academic and private entities to develop methods for using large electronic databases to actively monitor product safety. Important identified risks will have to be evaluated through observational studies and registries.

  8. Monitoring Device Safety in Interventional Cardiology

    OpenAIRE

    Matheny, Michael E.; Ohno-Machado, Lucila; Resnic, Frederic S.

    2006-01-01

    Objective: A variety of postmarketing surveillance strategies to monitor the safety of medical devices have been supported by the U.S. Food and Drug Administration, but there are few systems to automate surveillance. Our objective was to develop a system to perform real-time monitoring of safety data using a variety of process control techniques.

  9. Innovate or perish : The RSM Insight debate

    NARCIS (Netherlands)

    R. Gilbert (Russell)

    2014-01-01

    markdownabstract__Abstract__ Although innovation is one the hottest management topics of the 21st century, very few firms excel at it. Here, in the first RSM Insight debate, three of the school’s leading management scholars discuss how firms should approach the subject of innovation and what

  10. Radioactive Scrap Metal (RSM) recycling: A doe white paper

    International Nuclear Information System (INIS)

    Chatterjee, S.; Moore, H.H.; Ghoshal, A.

    1992-01-01

    An effective White Paper on recycling radioactive scrap metals has been drafted at the request of the U.S. Department of Energy (DOE) recently. The paper has received the praise and commendation of the DOE's Director of Environmental Management. However, obstructionist posturing by the petty bureaucrats in DOE continues to plague the meaningful implementation of RSM recycling. The key findings of the White Paper study and its major recommendations have discussed in this paper. The study indicates that several technologies, such as melt refining and electro refining, are currently available for surface and volume decontamination of metals. The unit cost of decontamination was found to vary from $700 to $400/ton; recycling of most low-contaminated metals can therefore be cost-effective vis-a vis the average cost of low-level radioactive wastes disposal of %400 to $2800/ton. Major recycling demonstration projects with emphasis on restricted RSM reuse options have been recommended. Volume contamination standard for unrestricted release should be established only after adequate studies of health effects and scientific/industrial effects of RSM reuse has been conducted by the Environmental Protection Agency (EPA) and the Nuclear Regulatory Commission (NRC). Some of the significant technical data developed during this study have also been briefly discussed in this paper. (author)

  11. The arrangement of deformation monitoring project and analysis of monitoring data of a hydropower engineering safety monitoring system

    Science.gov (United States)

    Wang, Wanshun; Chen, Zhuo; Li, Xiuwen

    2018-03-01

    The safety monitoring is very important in the operation and management of water resources and hydropower projects. It is the important means to understand the dam running status, to ensure the dam safety, to safeguard people’s life and property security, and to make full use of engineering benefits. This paper introduces the arrangement of engineering safety monitoring system based on the example of a water resource control project. The monitoring results of each monitoring project are analyzed intensively to show the operating status of the monitoring system and to provide useful reference for similar projects.

  12. Innovate or perish: The RSM Insight debate

    OpenAIRE

    Gilbert, Russell

    2014-01-01

    markdownabstract__Abstract__ Although innovation is one the hottest management topics of the 21st century, very few firms excel at it. Here, in the first RSM Insight debate, three of the school’s leading management scholars discuss how firms should approach the subject of innovation and what it takes to be successful at it.

  13. Monitoring circuit for reactor safety systems

    Science.gov (United States)

    Keefe, Donald J.

    1976-01-01

    The ratio between the output signals of a pair of reactor safety channels is monitored. When ratio falls outside of a predetermined range, it indicates that one or more of the safety channels has malfunctioned.

  14. Regional Sediment Management (RSM) Principles in Flood Recovery: Incorporating RSM after the 2011 Missouri River Flood

    Science.gov (United States)

    2013-06-01

    project also included adding seepage blankets in mul- tiple areas along the landward side of the lev- ee. At the Upper Hamburg Chute site, less than...that served as the downstream shore of the spillway pond. The pond is part of a recreation area and serves as a wa- ter intake for the Garrison fish ...Corps of Engineers (USACE) Re- gional Sediment Management (RSM) principles into a wide variety of projects as part of flood recov- ery and

  15. Monitoring circuit for reactor safety systems

    International Nuclear Information System (INIS)

    Keefe, D.J.

    1976-01-01

    The ratio between the output signals of a pair of reactor safety channels is monitored. When ratio falls outside of a predetermined range, it indicates that one or more of the safety channels has malfunctioned. 3 claims, 2 figures

  16. Tuning permissiveness of active safety monitors for autonomous systems

    OpenAIRE

    Masson , Lola; Guiochet , Jérémie; Waeselynck , Hélène; Cabrera , Kalou; Cassel , Sofia; Törngren , Martin

    2018-01-01

    International audience; Robots and autonomous systems have become a part of our everyday life, therefore guaranteeing their safety is crucial.Among the possible ways to do so, monitoring is widely used, but few methods exist to systematically generate safety rules to implement such monitors. Particularly, building safety monitors that do not constrain excessively the system's ability to perform its tasks is necessary as those systems operate with few human interventions.We propose in this pap...

  17. Risk monitor - a tool for operational safety assessment risk monitor - user's manual

    International Nuclear Information System (INIS)

    Hari Prasad, M.; Vinod, Gopika; Saraf, R.K.; Ghosh, A.K.

    2006-06-01

    Probabilistic Safety Assessment has become a key tool as on today to identify and understand Nuclear Power Plant vulnerabilities. As a result of the availability of these PSA studies, there is a desire to use them to enhance plant safety and to operate the nuclear stations in the most efficient manner. Risk Monitor is a PC based tool, which computes the real time safety level and assists plant personnel to manage day-to-day activities. Risk Monitor is a PC based user friendly software tool used for modification and re-analysis of a nuclear Power plant. Operation of Risk Monitor is based on PSA methods for assisting in day to day applications. Risk Monitoring programs can assess the risk profile and are used to optimize the operation of Nuclear Power Plants with respect to a minimum risk level over the operating time. This report presents the background activities of Risk Monitor, its application areas and the step by step procedure for the user.to interact with the software. This software can be used with the PSA model of any Nuclear Power Plant. (author)

  18. Quality and Safety of Home ICP Monitoring Compared with In-Hospital Monitoring

    DEFF Research Database (Denmark)

    Andresen, Morten; Juhler, Marianne; Munch, Tina Nørgaard

    2012-01-01

    Introduction: Intracranial pressure (ICP) monitoring is usually conducted in-hospital using stationary devices. Modern mobile ICP monitoring systems present new monitoring possibilities more closely following the patients' daily life. We reviewed patient safety, quality of technical data...

  19. The Pseudomonas transcriptional regulator AlgR controls LipA expression via the noncoding RNA RsmZ in Pseudomonas protegens Pf-5.

    Science.gov (United States)

    Li, Menggang; Yan, Jinyong; Yan, Yunjun

    2017-05-20

    Pseudomonas lipases are well studied enzymes. However, few studies have been conducted to explore the mechanism underlying the regulation of lipases expression. AlgR, a global regulator, controls the expression of multiple genes, regulates bacterial peristalsis, and participates in the regulation of quorum-sensing (QS) system, and so on. In this study, the effect of AlgR on lipase expression was investigated by knocking out the algR and rsmZ genes or overexpressing them. It is found out that AlgR can regulate the expression of lipA at both transcriptional and translational levels, but the transcriptional level was dominant. AlgR is also able to regulate the expression of rsmX/rsmY/rsmZ. Additionally, using algR/rsmZ double gene knock-out, it showed that AlgR could directly bind to the promoter sequence of rsmZ to regulate lipA activity. In conclusion, this study for the first time indicates that AlgR directly binds to rsmZ to regulates the expression of lipA via regulating transcription of rsmZ, and mainly regulates the expression of lipA at transcriptional level in P. protegens Pf-5. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Intelligent monitoring-based safety system of massage robot

    Institute of Scientific and Technical Information of China (English)

    胡宁; 李长胜; 王利峰; 胡磊; 徐晓军; 邹雲鹏; 胡玥; 沈晨

    2016-01-01

    As an important attribute of robots, safety is involved in each link of the full life cycle of robots, including the design, manufacturing, operation and maintenance. The present study on robot safety is a systematic project. Traditionally, robot safety is defined as follows: robots should not collide with humans, or robots should not harm humans when they collide. Based on this definition of robot safety, researchers have proposed ex ante and ex post safety standards and safety strategies and used the risk index and risk level as the evaluation indexes for safety methods. A massage robot realizes its massage therapy function through applying a rhythmic force on the massage object. Therefore, the traditional definition of safety, safety strategies, and safety realization methods cannot satisfy the function and safety requirements of massage robots. Based on the descriptions of the environment of massage robots and the tasks of massage robots, the present study analyzes the safety requirements of massage robots; analyzes the potential safety dangers of massage robots using the fault tree tool; proposes an error monitoring-based intelligent safety system for massage robots through monitoring and evaluating potential safety danger states, as well as decision making based on potential safety danger states; and verifies the feasibility of the intelligent safety system through an experiment.

  1. Optimisation of process parameters on thin shell part using response surface methodology (RSM)

    Science.gov (United States)

    Faiz, J. M.; Shayfull, Z.; Nasir, S. M.; Fathullah, M.; Rashidi, M. M.

    2017-09-01

    This study is carried out to focus on optimisation of process parameters by simulation using Autodesk Moldflow Insight (AMI) software. The process parameters are taken as the input in order to analyse the warpage value which is the output in this study. There are some significant parameters that have been used which are melt temperature, mould temperature, packing pressure, and cooling time. A plastic part made of Polypropylene (PP) has been selected as the study part. Optimisation of process parameters is applied in Design Expert software with the aim to minimise the obtained warpage value. Response Surface Methodology (RSM) has been applied in this study together with Analysis of Variance (ANOVA) in order to investigate the interactions between parameters that are significant to the warpage value. Thus, the optimised warpage value can be obtained using the model designed using RSM due to its minimum error value. This study comes out with the warpage value improved by using RSM.

  2. RSM Outlook Summer 2008 : Entrepreneurship: The Leap of Faith

    NARCIS (Netherlands)

    R. Morris (Rebecca); L. Sawahata (Lesa)

    2008-01-01

    markdownabstract#### What it takes to be an entrepreneur (Stephen Hoare, Rebecca Morris) Starting your own business is the stuff of capitalist dreams, with multitudes leaving behind the comfort of their salaried positions each year to attempt it. These RSM alumni are lucky enough to be able to

  3. Potential RSM Projects: West Maui Region, Maui, Hawaii

    Science.gov (United States)

    2016-02-01

    Hawaii by Thomas D. Smith BACKGROUND: The Hawaii West Maui Region (Figure 1) was the focus of Hawaii Regional Sediment Management (RSM...Conservation Service; Hawaii Department of Land and Natural Resources, Division of Aquatic Resources; Hawaii Department of Transportation; Maui...County; University of Hawaii , Sea Grant; Sea Engineering, Inc.; Maui Nui Marine Resource Council; Coral Reef Alliance; The Nature Conservancy; Henningson

  4. Structural Insights into the Methylation of C1402 in 16S rRNA by Methyltransferase RsmI.

    Directory of Open Access Journals (Sweden)

    Mohan Zhao

    Full Text Available RsmI and RsmH are conserved S-Adenosylmethionine (AdoMet-dependent methyltransferases (MTases that are responsible for the 2'-O-methylation and N4-methylation of C1402 in bacterial 16S rRNA, respectively. Methylation of m4Cm1402 plays a role in fine-tuning the shape and functions of the P-site to increase the decoding fidelity, and was recently found to contribute to the virulence of Staphylococcus aureus in host animals. Here we report the 2.20-Å crystal structure of homodimeric RsmI from Escherichia coli in complex with the cofactor AdoMet. RsmI consists of an N-terminal putative RNA-binding domain (NTD and a C-terminal catalytic domain (CTD with a Rossmann-like fold, and belongs to the class III MTase family. AdoMet is specifically bound into a negatively charged deep pocket formed by both domains by making extensive contacts. Structure-based mutagenesis and isothermal titration calorimetry (ITC assays revealed Asp100 and Ala124 are vital for AdoMet-binding. Although the overall fold of RsmI shows remarkable similarities to the characterized MTases involved in vitamin B12 biosynthesis, it exhibits a distinct charge distribution especially around the AdoMet-binding pocket because of different substrate specificity. The docking model of RsmI-AdoMet-RNA ternary complex suggested a possible base-flipping mechanism of the substrate RNA that has been observed in several known RNA MTases. Our structural and biochemical studies provide novel insights into the catalytic mechanism of C1402 methylation in 16S rRNA.

  5. Regional Sediment Management (RSM) Modeling Tools: Integration of Advanced Sediment Transport Tools into HEC-RAS

    Science.gov (United States)

    2014-06-01

    sediment transport within the USACE HEC River Analysis System ( HEC - RAS ) software package and to determine its applicability to Regional Sediment...Management (RSM) challenges. HEC - RAS SEDIMENT MODELING BACKGROUND: HEC - RAS performs (1) one- dimensional (1D) steady and unsteady hydraulic river ...Albuquerque (SPA)), and recently, the USACE RSM Program. HEC - RAS is one of several hydraulic modeling codes available for river analysis in the

  6. Therapeutic Drug Monitoring of Lithium

    DEFF Research Database (Denmark)

    Mose, Tina; Damkier, Per; Petersen, Magnus

    2015-01-01

    BACKGROUND: Serum lithium is monitored to ensure levels within the narrow therapeutic window. This study examines the interlaboratory variation and inaccuracy of lithium monitoring in Denmark. METHODS: In 16 samples consisting of (1) control materials (n = 4), (2) pooled patient serum (n = 5......), and (3) serum from individual patients (n = 7), lithium was measured in 19 laboratories using 20 different instruments. The lithium concentrations were targeted by a reference laboratory. Ion-selective electrode (n = 5), reflective spectrophotometric (RSM, n = 5), and spectrophotometric (n = 10) methods...... of >12%. Seven of these instruments had a systematic positive or negative bias and more so at lower lithium concentrations. Three poorly calibrated instruments were found in the ion-selective electrode group, 3 in the spectrophotometric group, and 2 in the RSM group. The instruments using reflectance...

  7. Safety Culture Monitoring: How to Assess Safety Culture in Real Time?

    International Nuclear Information System (INIS)

    Zronek, B.; Maryska, J.; Treslova, L.

    2016-01-01

    Do you know what is current level of safety culture in your company? Are you able to follow trend changes? Do you know what your recent issues are? Since safety culture is understood as vital part of nuclear industry daily life, it is crucial to know what the current level is. It is common to perform safety culture survey or ad hoc assessment. This contribution shares Temelin NPP, CEZ approach how to assess safety culture level permanently. Using behavioral related outputs of gap solving system, observation program, dedicated surveys, regulatory assessment, etc., allows creating real time safety culture monitoring without the need to perform any other activities. (author)

  8. Techno-economical optimization of Reactive Blue 19 removal by combined electrocoagulation/coagulation process through MOPSO using RSM and ANFIS models.

    Science.gov (United States)

    Taheri, M; Alavi Moghaddam, M R; Arami, M

    2013-10-15

    In this research, Response Surface Methodology (RSM) and Adaptive Neuro Fuzzy Inference System (ANFIS) models were applied for optimization of Reactive Blue 19 removal using combined electrocoagulation/coagulation process through Multi-Objective Particle Swarm Optimization (MOPSO). By applying RSM, the effects of five independent parameters including applied current, reaction time, initial dye concentration, initial pH and dosage of Poly Aluminum Chloride were studied. According to the RSM results, all the independent parameters are equally important in dye removal efficiency. In addition, ANFIS was applied for dye removal efficiency and operating costs modeling. High R(2) values (≥85%) indicate that the predictions of RSM and ANFIS models are acceptable for both responses. ANFIS was also used in MOPSO for finding the best techno-economical Reactive Blue 19 elimination conditions according to RSM design. Through MOPSO and the selected ANFIS model, Minimum and maximum values of 58.27% and 99.67% dye removal efficiencies were obtained, respectively. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. Optimisation on processing parameters for minimising warpage on side arm using response surface methodology (RSM) and particle swarm optimisation (PSO)

    Science.gov (United States)

    Rayhana, N.; Fathullah, M.; Shayfull, Z.; Nasir, S. M.; Hazwan, M. H. M.; Sazli, M.; Yahya, Z. R.

    2017-09-01

    This study presents the application of optimisation method to reduce the warpage of side arm part. Autodesk Moldflow Insight software was integrated into this study to analyse the warpage. The design of Experiment (DOE) for Response Surface Methodology (RSM) was constructed and by using the equation from RSM, Particle Swarm Optimisation (PSO) was applied. The optimisation method will result in optimised processing parameters with minimum warpage. Mould temperature, melt temperature, packing pressure, packing time and cooling time was selected as the variable parameters. Parameters selection was based on most significant factor affecting warpage stated by previous researchers. The results show that warpage was improved by 28.16% for RSM and 28.17% for PSO. The warpage improvement in PSO from RSM is only by 0.01 %. Thus, the optimisation using RSM is already efficient to give the best combination parameters and optimum warpage value for side arm part. The most significant parameters affecting warpage are packing pressure.

  10. Optimization of Nd: YAG Laser Marking of Alumina Ceramic Using RSM And ANN

    International Nuclear Information System (INIS)

    Peter, Josephine; Doloi, B.; Bhattacharyya, B.

    2011-01-01

    The present research papers deals with the artificial neural network (ANN) and the response surface methodology (RSM) based mathematical modeling and also an optimization analysis on marking characteristics on alumina ceramic. The experiments have been planned and carried out based on Design of Experiment (DOE). It also analyses the influence of the major laser marking process parameters and the optimal combination of laser marking process parametric setting has been obtained. The output of the RSM optimal data is validated through experimentation and ANN predictive model. A good agreement is observed between the results based on ANN predictive model and actual experimental observations.

  11. Optimization of surface integrity in dry hard turning using RSM

    Indian Academy of Sciences (India)

    This paper investigates the effect of different cutting parameters (cutting ... with coated carbide tool under different settings of cutting parameters. ... procedure of response surface methodology (RSM) to determine optimal ..... The numerical opti- .... and analysis of experiments, New Delhi, A. K. Ghosh, PHI Learning Private.

  12. Deploying response surface methodology (RSM) and glowworm swarm optimization (GSO) in optimizing warpage on a mobile phone cover

    Science.gov (United States)

    Lee, X. N.; Fathullah, M.; Shayfull, Z.; Nasir, S. M.; Hazwan, M. H. M.; Shazzuan, S.

    2017-09-01

    Plastic injection moulding is a popular manufacturing method not only it is reliable, but also efficient and cost saving. It able to produce plastic part with detailed features and complex geometry. However, defects in injection moulding process degrades the quality and aesthetic of the injection moulded product. The most common defect occur in the process is warpage. Inappropriate process parameter setting of injection moulding machine is one of the reason that leads to the occurrence of warpage. The aims of this study were to improve the quality of injection moulded part by investigating the optimal parameters in minimizing warpage using Response Surface Methodology (RSM) and Glowworm Swarm Optimization (GSO). Subsequent to this, the most significant parameter was identified and recommended parameters setting was compared with the optimized parameter setting using RSM and GSO. In this research, the mobile phone case was selected as case study. The mould temperature, melt temperature, packing pressure, packing time and cooling time were selected as variables whereas warpage in y-direction was selected as responses in this research. The simulation was carried out by using Autodesk Moldflow Insight 2012. In addition, the RSM was performed by using Design Expert 7.0 whereas the GSO was utilized by using MATLAB. The warpage in y direction recommended by RSM were reduced by 70 %. The warpages recommended by GSO were decreased by 61 % in y direction. The resulting warpages under optimal parameter setting by RSM and GSO were validated by simulation in AMI 2012. RSM performed better than GSO in solving warpage issue.

  13. Risk-based reconfiguration of safety monitoring system using dynamic Bayesian network

    International Nuclear Information System (INIS)

    Kohda, Takehisa; Cui Weimin

    2007-01-01

    To prevent an abnormal event from leading to an accident, the role of its safety monitoring system is very important. The safety monitoring system detects symptoms of an abnormal event to mitigate its effect at its early stage. As the operation time passes by, the sensor reliability decreases, which implies that the decision criteria of the safety monitoring system should be modified depending on the sensor reliability as well as the system reliability. This paper presents a framework for the decision criteria (or diagnosis logic) of the safety monitoring system. The logic can be dynamically modified based on sensor output data monitored at regular intervals to minimize the expected loss caused by two types of safety monitoring system failure events: failed-dangerous (FD) and failed-safe (FS). The former corresponds to no response under an abnormal system condition, while the latter implies a spurious activation under a normal system condition. Dynamic Bayesian network theory can be applied to modeling the entire system behavior composed of the system and its safety monitoring system. Using the estimated state probabilities, the optimal decision criterion is given to obtain the optimal diagnosis logic. An illustrative example of a three-sensor system shows the merits and characteristics of the proposed method, where the reasonable interpretation of sensor data can be obtained

  14. Monitoring and reviewing research reactor safety in Australia

    International Nuclear Information System (INIS)

    Cairns, R.C.; Greenslade, G.K.

    1990-01-01

    Th research reactors operated by the Australian Nuclear Science and Technology Organization (ANSTO) comprise the 10 MW reactor HIFAR and the 100 kW reactor Moata. Although there are no power reactors in Australia the problems and issues of public concern which arise in the operation of research reactors are similar to those of power reactors although on a smaller scale. The need for independent safety surveillance has been recognized by the Australian Government and the ANSTO Act, 1987, required the Board of ANSTO to establish a Nuclear Safety Bureau (NSB) with responsibility to the Minister for monitoring and reviewing the safety of nuclear plant operated by ANSTO. The Executive Director of ANSTO operates HIFAR subject to compliance with requirements and arrangements contained in a formal Authorization from the Board of ANSTO. A Ministerial Direction to the Board of ANSTO requires the NSB to report to him, on a quarterly basis, matters relating to its functions of monitoring and reviewing the safety of ANSTO's nuclear plant. Experience has shown that the Authorization provides a suitable framework for the operational requirements and arrangements to be organised in a disciplined and effective manner, and also provides a basis for audits by the NSB by which compliance with the Board's safety requirements are monitored. Examples of the way in which the NSB undertakes its monitoring and reviewing role are given. Moata, which has a much lower operating power level and fission product inventory than HIFAR, has not been subject to a formal Authorization to date but one is under preparation

  15. 78 FR 12065 - Patient Safety Organizations: Delisting for Cause for Independent Data Safety Monitoring, Inc.

    Science.gov (United States)

    2013-02-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Healthcare Research and Quality Patient Safety... Safety Monitoring, Inc. due to its failure to correct a deficiency. The Patient Safety and Quality Improvement Act of 2005 (Patient Safety Act) authorizes the listing of PSOs, which are entities or component...

  16. A sensor monitoring system for telemedicine, safety and security applications

    Science.gov (United States)

    Vlissidis, Nikolaos; Leonidas, Filippos; Giovanis, Christos; Marinos, Dimitrios; Aidinis, Konstantinos; Vassilopoulos, Christos; Pagiatakis, Gerasimos; Schmitt, Nikolaus; Pistner, Thomas; Klaue, Jirka

    2017-02-01

    A sensor system capable of medical, safety and security monitoring in avionic and other environments (e.g. homes) is examined. For application inside an aircraft cabin, the system relies on an optical cellular network that connects each seat to a server and uses a set of database applications to process data related to passengers' health, safety and security status. Health monitoring typically encompasses electrocardiogram, pulse oximetry and blood pressure, body temperature and respiration rate while safety and security monitoring is related to the standard flight attendance duties, such as cabin preparation for take-off, landing, flight in regions of turbulence, etc. In contrast to previous related works, this article focuses on the system's modules (medical and safety sensors and associated hardware), the database applications used for the overall control of the monitoring function and the potential use of the system for security applications. Further tests involving medical, safety and security sensing performed in an real A340 mock-up set-up are also described and reference is made to the possible use of the sensing system in alternative environments and applications, such as health monitoring within other means of transport (e.g. trains or small passenger sea vessels) as well as for remotely located home users, over a wired Ethernet network or the Internet.

  17. The Gac/Rsm Signaling Pathway of a Biocontrol Bacterium, Pseudomonas chlororaphis O6

    Directory of Open Access Journals (Sweden)

    Anne J. Anderson

    2017-09-01

    Full Text Available Pseudomonas chlororaphis O6, isolated from the roots of dryland, field-grown commercial wheat in the USA, enhances plant health and therefore it is used in agriculture as a biofertilizer and biocontrol agent. The metabolites produced by this pseudomonad stimulate plant growth through direct antagonism of pathogens and by inducing systemic resistance in the plant. Studies upon P. chlororaphis O6 identify the pathways through which defined bacterial metabolites generate protection against pathogenic microbes, insects, and nematodes. P. chlororaphis O6 also triggers plant resistance to drought and salinity stresses. The beneficial determinants are produced from bacterial cells as they form biofilms during root colonization. Molecular control these processes in P. chlororaphis O6 involves the global regulatory Gac/Rsm signaling cascade with cross-talk between other global regulatory pathways. The Gac/Rsm regulon allows for coordinate phasing of expression of the genes that encode these beneficial traits among a community of cells. This review provides insights on the Gac/Rsm regulon in expression of beneficial traits of the P. chlororaphis O6 which can contribute to help yield enhancement and quality in agricultural production.

  18. Optimisation of warpage on plastic injection moulding part using response surface methodology (RSM) and genetic algorithm method (GA)

    Science.gov (United States)

    Miza, A. T. N. A.; Shayfull, Z.; Nasir, S. M.; Fathullah, M.; Hazwan, M. H. M.

    2017-09-01

    In this study, Computer Aided Engineering was used for injection moulding simulation. The method of Design of experiment (DOE) was utilize according to the Latin Square orthogonal array. The relationship between the injection moulding parameters and warpage were identify based on the experimental data that used. Response Surface Methodology (RSM) was used as to validate the model accuracy. Then, the RSM and GA method were combine as to examine the optimum injection moulding process parameter. Therefore the optimisation of injection moulding is largely improve and the result shown an increasing accuracy and also reliability. The propose method by combining RSM and GA method also contribute in minimising the warpage from occur.

  19. Optimisation of process parameters on thin shell part using response surface methodology (RSM) and genetic algorithm (GA)

    Science.gov (United States)

    Faiz, J. M.; Shayfull, Z.; Nasir, S. M.; Fathullah, M.; Hazwan, M. H. M.

    2017-09-01

    This study conducts the simulation on optimisation of injection moulding process parameters using Autodesk Moldflow Insight (AMI) software. This study has applied some process parameters which are melt temperature, mould temperature, packing pressure, and cooling time in order to analyse the warpage value of the part. Besides, a part has been selected to be studied which made of Polypropylene (PP). The combination of the process parameters is analysed using Analysis of Variance (ANOVA) and the optimised value is obtained using Response Surface Methodology (RSM). The RSM as well as Genetic Algorithm are applied in Design Expert software in order to minimise the warpage value. The outcome of this study shows that the warpage value improved by using RSM and GA.

  20. Optimization of Vehicle Suspension Parameters for Ride Comfort Based on RSM

    Science.gov (United States)

    Mitra, A. C.; Patil, M. V.; Banerjee, N.

    2015-04-01

    Vehicle suspension design requires an investigation to determine the spring and damper settings that assure optimal ride comfort (RC) of vehicle. In the present work response surface methodology (RSM), one of the methods of design of experiment has been successfully implemented for the purpose of finding optimal setting. Design of experiment sometimes requires accurate representation of the independent variables which are usually difficult to measure or else unavailable for experimentation. This paper proposes a simulation model to analyze the ride comfort with accurate independent variables as per Box-Behnken design of RSM. A prediction model of response variable, RC is developed using regression analysis which leads to a good agreement with simulated model ( R 2 = 99.74 %). The fitted model can be effectively used to evaluate optimal setting of spring stiffness and damping coefficient with the help of response optimization of a high desirability value.

  1. Temelin safety monitor

    International Nuclear Information System (INIS)

    Mlady, O.

    2000-01-01

    Temelin NPP is a WWER-1000/320 two unit plant under construction, originally designed according to the standards of the former Soviet Union. After a series of reviews in the 80s, a decision was taken to upgrade the design of Temelin, including the supply of fuel and instrumentation and instrumentation and control system (I and C). Details on the current design and other related safety matters were presented to the nuclear community in a meeting organized by the IAEA in November 1994. Based upon recommendations of IAEA OSART missions, post TMI requirements and Temelin Risk Audit recommendations it was decided to perform a Probabilistic Safety Assessment within the Temelin PSA Project. The general purpose of this project was to perform systematic examination of the Temelin Unit 1 NPP for severe accident vulnerabilities by performance of a Level 1 and 2 PSA study. In addition to the completion of Temelin documented living PSA model, the decision was to develop and implement a PSA based software tool able to analyze real and scheduled plant conditions for determining the risk impact of plant configurations and on-line maintenance activities. This paper provides an overview of the key features of the Temelin Safety Monitor, describes its development activities and its current status and intended use at Temelin NPP for PSA applications. (author)

  2. The Trk Potassium Transporter Is Required for RsmB-Mediated Activation of Virulence in the Phytopathogen Pectobacterium wasabiae.

    Science.gov (United States)

    Valente, Rita S; Xavier, Karina B

    2016-01-15

    Pectobacterium wasabiae (previously known as Erwinia carotovora) is an important plant pathogen that regulates the production of plant cell wall-degrading enzymes through an N-acyl homoserine lactone-based quorum sensing system and through the GacS/GacA two-component system (also known as ExpS/ExpA). At high cell density, activation of GacS/GacA induces the expression of RsmB, a noncoding RNA that is essential for the activation of virulence in this bacterium. A genetic screen to identify regulators of RsmB revealed that mutants defective in components of a putative Trk potassium transporter (trkH and trkA) had decreased rsmB expression. Further analysis of these mutants showed that changes in potassium concentration influenced rsmB expression and consequent tissue damage in potato tubers and that this regulation required an intact Trk system. Regulation of rsmB expression by potassium via the Trk system occurred even in the absence of the GacS/GacA system, demonstrating that these systems act independently and are both required for full activation of RsmB and for the downstream induction of virulence in potato infection assays. Overall, our results identified potassium as an essential environmental factor regulating the Rsm system, and the consequent induction of virulence, in the plant pathogen P. wasabiae. Crop losses from bacterial diseases caused by pectolytic bacteria are a major problem in agriculture. By studying the regulatory pathways involved in controlling the expression of plant cell wall-degrading enzymes in Pectobacterium wasabiae, we showed that the Trk potassium transport system plays an important role in the regulation of these pathways. The data presented further identify potassium as an important environmental factor in the regulation of virulence in this plant pathogen. We showed that a reduction in virulence can be achieved by increasing the extracellular concentration of potassium. Therefore, this work highlights how elucidation of the

  3. Multi-dimensional database design and implementation of dam safety monitoring system

    Directory of Open Access Journals (Sweden)

    Zhao Erfeng

    2008-09-01

    Full Text Available To improve the effectiveness of dam safety monitoring database systems, the development process of a multi-dimensional conceptual data model was analyzed and a logic design was achieved in multi-dimensional database mode. The optimal data model was confirmed by identifying data objects, defining relations and reviewing entities. The conversion of relations among entities to external keys and entities and physical attributes to tables and fields was interpreted completely. On this basis, a multi-dimensional database that reflects the management and analysis of a dam safety monitoring system on monitoring data information has been established, for which factual tables and dimensional tables have been designed. Finally, based on service design and user interface design, the dam safety monitoring system has been developed with Delphi as the development tool. This development project shows that the multi-dimensional database can simplify the development process and minimize hidden dangers in the database structure design. It is superior to other dam safety monitoring system development models and can provide a new research direction for system developers.

  4. Warpage investigation on side arms using response surface methodology (RSM) and glow-worm swarm optimizations (GSO)

    Science.gov (United States)

    Sow, C. K.; Fathullah, M.; Nasir, S. M.; Shayfull, Z.; Shazzuan, S.

    2017-09-01

    This paper discusses on an analysis run via injection moulding process in determination of the optimum processing parameters used for manufacturing side arms of catheters in minimizing the warpage issues. The optimization method used was RSM. Moreover, in this research tries to find the most significant factor affecting the warpage. From the previous literature review,4 most significant parameters on warpage defect was selected. Those parameters were melt temperature, packing time, packing pressure, mould temperature and cooling time. At the beginning, side arm was drawn using software of CATIA V5. Then, software Mouldflow and Design Expert were employed to analyses on the popular warpage issues. After that, GSO artificial intelligence was apply using the mathematical model from Design Expert for more optimization on RSM result. Recommended parameter settings from the simulation work were then compared with the optimization work of RSM and GSO. The result show that the warpage on the side arm was improved by 3.27 %

  5. Safety performance monitoring of autonomous marine systems

    International Nuclear Information System (INIS)

    Thieme, Christoph A.; Utne, Ingrid B.

    2017-01-01

    The marine environment is vast, harsh, and challenging. Unanticipated faults and events might lead to loss of vessels, transported goods, collected scientific data, and business reputation. Hence, systems have to be in place that monitor the safety performance of operation and indicate if it drifts into an intolerable safety level. This article proposes a process for developing safety indicators for the operation of autonomous marine systems (AMS). The condition of safety barriers and resilience engineering form the basis for the development of safety indicators, synthesizing and further adjusting the dual assurance and the resilience based early warning indicator (REWI) approaches. The article locates the process for developing safety indicators in the system life cycle emphasizing a timely implementation of the safety indicators. The resulting safety indicators reflect safety in AMS operation and can assist in planning of operations, in daily operational decision-making, and identification of improvements. Operation of an autonomous underwater vehicle (AUV) exemplifies the process for developing safety indicators and their implementation. The case study shows that the proposed process leads to a comprehensive set of safety indicators. It is expected that application of the resulting safety indicators consequently will contribute to safer operation of current and future AMS. - Highlights: • Process for developing safety indicators for autonomous marine systems. • Safety indicators based on safety barriers and resilience thinking. • Location of the development process in the system lifecycle. • Case study on AUV demonstrating applicability of the process.

  6. Performance Monitoring for Nuclear Safety Related Instrumentation at PUSPATI TRIGA Reactor (RTP)

    International Nuclear Information System (INIS)

    Zareen Khan Abdul Jalil Khan; Ridzuan Abdul Mutalib; Mohd Sabri Minhat

    2015-01-01

    The Reactor TRIGA PUSPATI (RTP) at Malaysia Nuclear Agency is a TRIGA Mark II type reactor and pool type cooled by natural circulation of light water. This paper describe on performance monitoring for nuclear safety related instrumentation in TRIGA PUSPATI Reactor (RTP) of based on various parameter of reactor safety instrument channel such as log power, linear power, Fuel temperature, coolant temperature will take into consideration. Methodology of performance on estimation and monitoring is to evaluate and analysis of reactor parameters which is important of reactor safety and control. And also to estimate power measurement, differential of log and linear power and fuel temperature during reactor start-up, operation and shutdown .This study also focus on neutron power fluctuation from fission chamber during reactor start-up and operation. This work will present result of performance monitoring from RTP which indicated the safety parameter identification and initiate safety action on crossing the threshold set point trip. Conclude that performance of nuclear safety related instrumentation will improved the reactor control and safety parameter during reactor start-up, operation and shutdown. (author)

  7. Safety valve opening and closing operation monitor

    International Nuclear Information System (INIS)

    Kodama, Kunio; Takeshima, Ikuo; Takahashi, Kiyokazu.

    1981-01-01

    Purpose: To enable the detection of the closing of a safety valve when the internal pressure in a BWR type reactor is a value which will close the safety valve, by inputting signals from a pressure detecting device mounted directly at a reactor vessel and a safety valve discharge pressure detecting device to an AND logic circuit. Constitution: A safety valve monitor is formed of a pressure switch mounted at a reactor pressure vessel, a pressure switch mounted at the exhaust pipe of the escape safety valve and a logic circuit and the lide. When the input pressure of the safety valve is raised so that the valve and the pressure switch mounted at the exhaust pipe are operated, an alarm is indicated, and the operation of the pressure switch mounted at a pressure vessel is eliminated. If the safety valve is not reclosed when the vessel pressure is decreased lower than the pressure at which it is to be reclosed after the safety valve is operated, an alarm is generated by the logic circuit since both the pressure switches are operated. (Sekiya, K.)

  8. Application of Response Surface Methodology (RSM for Optimization of Operating Parameters and Performance Evaluation of Cooling Tower Cold Water Temperature

    Directory of Open Access Journals (Sweden)

    Ramkumar RAMAKRISHNAN

    2012-01-01

    Full Text Available The performance of a cooling tower was analyzed with various operating parameters tofind the minimum cold water temperature. In this study, optimization of operating parameters wasinvestigated. An experimental design was carried out based on central composite design (CCD withresponse surface methodology (RSM. This paper presents optimum operating parameters and theminimum cold water temperature using the RSM method. The RSM was used to evaluate the effectsof operating variables and their interaction towards the attainment of their optimum conditions.Based on the analysis, air flow, hot water temperature and packing height were high significanteffect on cold water temperature. The optimum operating parameters were predicted using the RSMmethod and confirmed through experiment.

  9. The post-transcriptional regulator rsmA/csrA activates T3SS by stabilizing the 5' UTR of hrpG, the master regulator of hrp/hrc genes, in Xanthomonas.

    Directory of Open Access Journals (Sweden)

    Maxuel O Andrade

    2014-02-01

    Full Text Available The RsmA/CsrA family of the post-transcriptional regulators of bacteria is involved in the regulation of many cellular processes, including pathogenesis. In this study, we demonstrated that rsmA not only is required for the full virulence of the phytopathogenic bacterium Xanthomonas citri subsp. citri (XCC but also contributes to triggering the hypersensitive response (HR in non-host plants. Deletion of rsmA resulted in significantly reduced virulence in the host plant sweet orange and a delayed and weakened HR in the non-host plant Nicotiana benthamiana. Microarray, quantitative reverse-transcription PCR, western-blotting, and GUS assays indicated that RsmA regulates the expression of the type 3 secretion system (T3SS at both transcriptional and post-transcriptional levels. The regulation of T3SS by RsmA is a universal phenomenon in T3SS-containing bacteria, but the specific mechanism seems to depend on the interaction between a particular bacterium and its hosts. For Xanthomonads, the mechanism by which RsmA activates T3SS remains unknown. Here, we show that RsmA activates the expression of T3SS-encoding hrp/hrc genes by directly binding to the 5' untranslated region (UTR of hrpG, the master regulator of the hrp/hrc genes in XCC. RsmA stabilizes hrpG mRNA, leading to increased accumulation of HrpG proteins and subsequently, the activation of hrp/hrc genes. The activation of the hrp/hrc genes by RsmA via HrpG was further supported by the observation that ectopic overexpression of hrpG in an rsmA mutant restored its ability to cause disease in host plants and trigger HR in non-host plants. RsmA also stabilizes the transcripts of another T3SS-associated hrpD operon by directly binding to the 5' UTR region. Taken together, these data revealed that RsmA primarily activates T3SS by acting as a positive regulator of hrpG and that this regulation is critical to the pathogenicity of XCC.

  10. Environmental and Source Monitoring for Purposes of Radiation Protection. Safety Guide (Spanish ed.)

    International Nuclear Information System (INIS)

    2010-01-01

    The purpose of this Safety Guide is to provide international guidance, coherent with contemporary radiation protection principles and IAEA safety requirements, on the strategy of monitoring in relation to: (a) control of radionuclide discharges under practice conditions, and (b) intervention, such as in cases of nuclear or radiological emergencies or past contamination of areas with long lived radionuclides. Three categories of monitoring are discussed: monitoring at the source of the discharge (source monitoring), monitoring in the environment (environmental monitoring) and monitoring of individual exposure in emergencies (individual monitoring). The Safety Guide also provides general guidance on assessment of the doses to critical groups of the population due to the presence of radioactive materials or radiation fields in the environment both from routine operation of nuclear and other related facilities (practice) and from nuclear or radiological emergencies and past contamination of areas with long lived radionuclides (intervention). The dose assessments are based on the results of source monitoring, environmental monitoring, individual monitoring or their combinations. This Safety Guide is primarily intended for use by national regulatory bodies and other agencies involved in national systems of radiation monitoring, as well as by operators of nuclear installations and other facilities where natural or human made radionuclides are treated and monitored. Contents: 1. Introduction; 2. Meeting regulatory requirements for monitoring in practices and interventions; 3. Responsibilities for monitoring; 4. Generic aspects of monitoring programmes; 5. Programmes for monitoring in practices and interventions; 6. Technical conditions for monitoring procedures; 7. Considerations in dose assessment; 8. Interpretation of monitoring results; 9. Quality assurance; 10. Recording of results; 11. Education and training; Glossary.

  11. RNA-seq reveals the RNA binding proteins, Hfq and RsmA, play various roles in virulence, antibiotic production and genomic flux in Serratia sp. ATCC 39006.

    Science.gov (United States)

    Wilf, Nabil M; Reid, Adam J; Ramsay, Joshua P; Williamson, Neil R; Croucher, Nicholas J; Gatto, Laurent; Hester, Svenja S; Goulding, David; Barquist, Lars; Lilley, Kathryn S; Kingsley, Robert A; Dougan, Gordon; Salmond, George Pc

    2013-11-22

    Serratia sp. ATCC 39006 (S39006) is a Gram-negative enterobacterium that is virulent in plant and animal models. It produces a red-pigmented trypyrrole secondary metabolite, prodigiosin (Pig), and a carbapenem antibiotic (Car), as well as the exoenzymes, pectate lyase and cellulase. Secondary metabolite production in this strain is controlled by a complex regulatory network involving quorum sensing (QS). Hfq and RsmA (two RNA binding proteins and major post-transcriptional regulators of gene expression) play opposing roles in the regulation of several key phenotypes within S39006. Prodigiosin and carbapenem production was abolished, and virulence attenuated, in an S39006 ∆hfq mutant, while the converse was observed in an S39006 rsmA transposon insertion mutant. In order to define the complete regulon of Hfq and RsmA, deep sequencing of cDNA libraries (RNA-seq) was used to analyse the whole transcriptome of S39006 ∆hfq and rsmA::Tn mutants. Moreover, we investigated global changes in the proteome using an LC-MS/MS approach. Analysis of differential gene expression showed that Hfq and RsmA directly or indirectly regulate (at the level of RNA) 4% and 19% of the genome, respectively, with some correlation between RNA and protein expression. Pathways affected include those involved in antibiotic regulation, virulence, flagella synthesis, and surfactant production. Although Hfq and RsmA are reported to activate flagellum production in E. coli and an adherent-invasive E. coli hfq mutant was shown to have no flagella by electron microscopy, we found that flagellar production was increased in the S39006 rsmA and hfq mutants. Additionally, deletion of rsmA resulted in greater genomic flux with increased activity of two mobile genetic elements. This was confirmed by qPCR and analysis of rsmA culture supernatant revealed the presence of prophage DNA and phage particles. Finally, expression of a hypothetical protein containing DUF364 increased prodigiosin production and was

  12. Potential of acoustic monitoring for safety assessment of primary system

    International Nuclear Information System (INIS)

    Olma, B.J.

    1997-01-01

    Safety assessment of the primary system and its components with respect to their mechanical integrity is increasingly supported by acoustic signature analysis during power operation of the plants. Acoustic signals of Loose Parts Monitoring System sensors are continuously monitored by dedicated digital systems for signal bursts associated with metallic impacts. Several years of ISTec/GRS experience and the practical use of its digital systems MEDEA and RAMSES have shown that acoustic monitoring is very successful for detecting component failures at an early stage. Advanced powerful tools for classification and acoustic evaluation of burst signals have recently been realized. The paper presents diagnosis experiences of BWR's and PWR's safety assessment. (author). 7 refs, 8 figs

  13. [Establishment of model of traditional Chinese medicine injections post-marketing safety monitoring].

    Science.gov (United States)

    Guo, Xin-E; Zhao, Yu-Bin; Xie, Yan-Ming; Zhao, Li-Cai; Li, Yan-Feng; Hao, Zhe

    2013-09-01

    To establish a nurse based post-marketing safety surveillance model for traditional Chinese medicine injections (TCMIs). A TCMIs safety monitoring team and a research hospital team engaged in the research, monitoring processes, and quality control processes were established, in order to achieve comprehensive, timely, accurate and real-time access to research data, to eliminate errors in data collection. A triage system involving a study nurse, as the first point of contact, clinicians and clinical pharmacists was set up in a TCM hospital. Following the specified workflow involving labeling of TCM injections and using improved monitoring forms it was found that there were no missing reports at the ratio of error was zero. A research nurse as the first and main point of contact in post-marketing safety monitoring of TCM as part of a triage model, ensures that research data collected has the characteristics of authenticity, accuracy, timeliness, integrity, and eliminate errors during the process of data collection. Hospital based monitoring is a robust and operable process.

  14. Statistical optimization of the phytoremediation of arsenic by Ludwigia octovalvis- in a pilot reed bed using response surface methodology (RSM) versus an artificial neural network (ANN).

    Science.gov (United States)

    Titah, Harmin Sulistiyaning; Halmi, Mohd Izuan Effendi Bin; Abdullah, Siti Rozaimah Sheikh; Hasan, Hassimi Abu; Idris, Mushrifah; Anuar, Nurina

    2018-06-07

    In this study, the removal of arsenic (As) by plant, Ludwigia octovalvis, in a pilot reed bed was optimized. A Box-Behnken design was employed including a comparative analysis of both Response Surface Methodology (RSM) and an Artificial Neural Network (ANN) for the prediction of maximum arsenic removal. The predicted optimum condition using the desirability function of both models was 39 mg kg -1 for the arsenic concentration in soil, an elapsed time of 42 days (the sampling day) and an aeration rate of 0.22 L/min, with the predicted values of arsenic removal by RSM and ANN being 72.6% and 71.4%, respectively. The validation of the predicted optimum point showed an actual arsenic removal of 70.6%. This was achieved with the deviation between the validation value and the predicted values being within 3.49% (RSM) and 1.87% (ANN). The performance evaluation of the RSM and ANN models showed that ANN performs better than RSM with a higher R 2 (0.97) close to 1.0 and very small Average Absolute Deviation (AAD) (0.02) and Root Mean Square Error (RMSE) (0.004) values close to zero. Both models were appropriate for the optimization of arsenic removal with ANN demonstrating significantly higher predictive and fitting ability than RSM.

  15. ANN and RSM modelling of antioxidant characteristics of kombucha fermented milk beverages with peppermint

    Directory of Open Access Journals (Sweden)

    Jasmina Vitas

    2018-01-01

    Full Text Available Antioxidant activity to stable DPPH radical (AADPPH and unstable hydroxyl radicals (AA.OH and nutraceuticals (monounsaturated fatty acids (MUFAs, polyunsaturated fatty acids (PUFAs and ascorbic acid content of kombucha fermented milks with peppermint (KFM-P were modelled and optimised. Beverages were produced by the addition of 10 % of kombucha peppermint inoculum to the milk containing 0.8, 1.6 and 2.8 % milk fat at 37, 40 and 43 °C. Response surface methodology (RSM indicated opposite response surfaces for AADPPH and AA.OH PUFAs and ascorbic acid, as most significant and influential factors, were included in graphical optimization and gave the working region for obtaining products of highest antioxidant quality: lower temperatures and milk fat up to 1.8 %; higher temperatures and milk fat of maximum 1.6 %. ANN modelling of antioxidant characteristics of kombucha fermented milk beverages with peppermint was, as expected, more accurate than RSM.

  16. Design of Safety Parameter Monitoring Function in a Research Reactor Facility

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jaekwan; Suh, Yongsuk [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    The primary purpose of the safety parameter monitoring system (SPDS) is to help operating personnel in the control room make quick assessments of the plant safety status. Thus, the basic function of the SPDS is a provision of a continuous indication of plant parameters or derived variables representative of the safety status of the plant. NUREG-0737 Supplement 1 provides details of the functional criteria for the SPDS, as one of the action plan requirements from TMI accident. The system provides various functions as follows: · Alerting based on safety function decision logics, · Success path analysis to achieve the integrity of the safety functions, · 3 layer display architecture - safety function, success path display for each safety function, system summary and equipment details for each safety function, · Integration with computer-based procedure. According to a Notice of the NSSC No. 2012-31, a research reactor facility generating more than 2 MW of power should also be furnished with the SPDS for emergency preparedness. Generally, a research reactor is a small size facility, and its number of instrumentations is fewer than that of NPPs. In particular, it is actually hard to have various and powerful functions from an economic perspective. Therefore, a safety parameter display system optimized for a research reactor facility must be proposed. This paper provides the requirement analysis results and proposes the design of safety parameter monitoring function for a research reactor. The safety parameter monitoring function supporting control room personnel during emergency conditions should be designed in a research reactor facility. The facility size and number of signals are smaller than that of the power plants. Also, it is actually hard to have various and powerful functions of nuclear power plants from an economic perspective. Thus, a safety parameter display system optimized to a research reactor must be proposed. First, we found important design items

  17. Design of Safety Parameter Monitoring Function in a Research Reactor Facility

    International Nuclear Information System (INIS)

    Park, Jaekwan; Suh, Yongsuk

    2014-01-01

    The primary purpose of the safety parameter monitoring system (SPDS) is to help operating personnel in the control room make quick assessments of the plant safety status. Thus, the basic function of the SPDS is a provision of a continuous indication of plant parameters or derived variables representative of the safety status of the plant. NUREG-0737 Supplement 1 provides details of the functional criteria for the SPDS, as one of the action plan requirements from TMI accident. The system provides various functions as follows: · Alerting based on safety function decision logics, · Success path analysis to achieve the integrity of the safety functions, · 3 layer display architecture - safety function, success path display for each safety function, system summary and equipment details for each safety function, · Integration with computer-based procedure. According to a Notice of the NSSC No. 2012-31, a research reactor facility generating more than 2 MW of power should also be furnished with the SPDS for emergency preparedness. Generally, a research reactor is a small size facility, and its number of instrumentations is fewer than that of NPPs. In particular, it is actually hard to have various and powerful functions from an economic perspective. Therefore, a safety parameter display system optimized for a research reactor facility must be proposed. This paper provides the requirement analysis results and proposes the design of safety parameter monitoring function for a research reactor. The safety parameter monitoring function supporting control room personnel during emergency conditions should be designed in a research reactor facility. The facility size and number of signals are smaller than that of the power plants. Also, it is actually hard to have various and powerful functions of nuclear power plants from an economic perspective. Thus, a safety parameter display system optimized to a research reactor must be proposed. First, we found important design items

  18. Development of Operational Safety Monitoring System and Emergency Preparedness Advisory System for CANDU Reactors (I)

    International Nuclear Information System (INIS)

    Kim, Ma Woong; Shin, Hyeong Ki; Lee, Sang Kyu; Kim, Hyun Koon; Yoo, Kun Joong; Ryu, Yong Ho; Son, Han Seong; Song, Deok Yong

    2007-01-01

    As increase of operating nuclear power plants, an accident monitoring system is essential to ensure the operational safety of nuclear power plant. Thus, KINS has developed the Computerized Advisory System for a Radiological Emergency (CARE) system to monitor the operating status of nuclear power plant continuously. However, during the accidents or/and incidents some parameters could not be provided from the process computer of nuclear power plant to the CARE system due to limitation of To enhance the CARE system more effective for CANDU reactors, there is a need to provide complement the feature of the CARE in such a way to providing the operating parameters using to using safety analysis tool such as CANDU Integrated Safety Analysis System (CISAS) for CANDU reactors. In this study, to enhance the safety monitoring measurement two computerized systems such as a CANDU Operational Safety Monitoring System (COSMOS) and prototype of CANDU Emergency Preparedness Advisory System (CEPAS) are developed. This study introduces the two integrated safety monitoring system using the R and D products of the national mid- and long-term R and D such as CISAS and ISSAC code

  19. Safety Criteria and Standards for Bearing Capacity of Foundation

    Directory of Open Access Journals (Sweden)

    Yanlong Li

    2017-01-01

    Full Text Available This paper focuses on the evaluation standards of factor of safety for foundation stability analysis. The problem of foundation stability is analyzed via the methods of risk analysis of engineering structures and reliability-based design, and the factor of safety for foundation stability is determined by using bearing capacity safety-factor method (BSFM and strength safety-factor method (SSFM. Based on a typical example, the admissible factors of safety were calibrated with a target reliability index specified in relevant standards. Two safety criteria and their standards of bearing capacity of foundation for these two methods (BSFM and SSFM were established. The universality of the safety criteria and their standards for foundation reliability was verified based on the concept of the ratio of safety margin (RSM.

  20. Regulatory network controlling extracellular proteins in Erwinia carotovora subsp. carotovora: FlhDC, the master regulator of flagellar genes, activates rsmB regulatory RNA production by affecting gacA and hexA (lrhA) expression.

    Science.gov (United States)

    Cui, Yaya; Chatterjee, Asita; Yang, Hailian; Chatterjee, Arun K

    2008-07-01

    Erwinia carotovora subsp. carotovora produces an array of extracellular proteins (i.e., exoproteins), including plant cell wall-degrading enzymes and Harpin, an effector responsible for eliciting hypersensitive reaction. Exoprotein genes are coregulated by the quorum-sensing signal, N-acyl homoserine lactone, plant signals, an assortment of transcriptional factors/regulators (GacS/A, ExpR1, ExpR2, KdgR, RpoS, HexA, and RsmC) and posttranscriptional regulators (RsmA, rsmB RNA). rsmB RNA production is positively regulated by GacS/A, a two-component system, and negatively regulated by HexA (PecT in Erwinia chrysanthemi; LrhA [LysR homolog A] in Escherichia coli) and RsmC, a putative transcriptional adaptor. While free RsmA, an RNA-binding protein, promotes decay of mRNAs of exoprotein genes, binding of RsmA with rsmB RNA neutralizes the RsmA effect. In the course of studies of GacA regulation, we discovered that a locus bearing strong homology to the flhDC operon of E. coli also controls extracellular enzyme production. A transposon insertion FlhDC(-) mutant produces very low levels of pectate lyase, polygalacturonase, cellulase, protease, and E. carotovora subsp. carotovora Harpin (Harpin(Ecc)) and is severely attenuated in its plant virulence. The production of these exoproteins is restored in the mutant carrying an FlhDC(+) plasmid. Sequence analysis and transcript assays disclosed that the flhD operon of E. carotovora subsp. carotovora, like those of other enterobacteria, consists of flhD and flhC. Complementation analysis revealed that the regulatory effect requires functions of both flhD and flhC products. The data presented here show that FlhDC positively regulates gacA, rsmC, and fliA and negatively regulates hexA (lrhA). Evidence shows that FlhDC controls extracellular protein production through cumulative effects on hexA and gacA. Reduced levels of GacA and elevated levels of HexA in the FlhDC(-) mutant are responsible for the inhibition of rsmB RNA

  1. Regulatory Network Controlling Extracellular Proteins in Erwinia carotovora subsp. carotovora: FlhDC, the Master Regulator of Flagellar Genes, Activates rsmB Regulatory RNA Production by Affecting gacA and hexA (lrhA) Expression▿

    Science.gov (United States)

    Cui, Yaya; Chatterjee, Asita; Yang, Hailian; Chatterjee, Arun K.

    2008-01-01

    Erwinia carotovora subsp. carotovora produces an array of extracellular proteins (i.e., exoproteins), including plant cell wall-degrading enzymes and Harpin, an effector responsible for eliciting hypersensitive reaction. Exoprotein genes are coregulated by the quorum-sensing signal, N-acyl homoserine lactone, plant signals, an assortment of transcriptional factors/regulators (GacS/A, ExpR1, ExpR2, KdgR, RpoS, HexA, and RsmC) and posttranscriptional regulators (RsmA, rsmB RNA). rsmB RNA production is positively regulated by GacS/A, a two-component system, and negatively regulated by HexA (PecT in Erwinia chrysanthemi; LrhA [LysR homolog A] in Escherichia coli) and RsmC, a putative transcriptional adaptor. While free RsmA, an RNA-binding protein, promotes decay of mRNAs of exoprotein genes, binding of RsmA with rsmB RNA neutralizes the RsmA effect. In the course of studies of GacA regulation, we discovered that a locus bearing strong homology to the flhDC operon of E. coli also controls extracellular enzyme production. A transposon insertion FlhDC− mutant produces very low levels of pectate lyase, polygalacturonase, cellulase, protease, and E. carotovora subsp. carotovora Harpin (HarpinEcc) and is severely attenuated in its plant virulence. The production of these exoproteins is restored in the mutant carrying an FlhDC+ plasmid. Sequence analysis and transcript assays disclosed that the flhD operon of E. carotovora subsp. carotovora, like those of other enterobacteria, consists of flhD and flhC. Complementation analysis revealed that the regulatory effect requires functions of both flhD and flhC products. The data presented here show that FlhDC positively regulates gacA, rsmC, and fliA and negatively regulates hexA (lrhA). Evidence shows that FlhDC controls extracellular protein production through cumulative effects on hexA and gacA. Reduced levels of GacA and elevated levels of HexA in the FlhDC− mutant are responsible for the inhibition of rsmB RNA production

  2. [Necessity of applying pharmacovigilance in post-marketing safety monitoring of traditional Chinese medicine injections].

    Science.gov (United States)

    Wang, Hai-Nan; Chen, Wen; Fu, Zheng; Du, Wen-min; He, Jia

    2008-03-01

    Traditional Chinese medicine (TCM) injection has become one of the hotspots in the new TCM research and development. The serious adverse drug reactions happened in clinical have arosed attention widely in the whole society. It's very urgent to monitor the post-marketing safety of TCM injections. This paper elucidated the pharmacovigilance's necessity in the post-marketing safety monitoring of TCM injections, basing on the reason of safety problem of TCM injections and the future developing trend of adverse drug reaction monitoring. Also, this paper introduced the rapid signal detection method of spontaneous reporting system database by data mining technology.

  3. Safety measurement and monitoring in healthcare: a framework to guide clinical teams and healthcare organisations in maintaining safety

    Science.gov (United States)

    Vincent, Charles; Burnett, Susan; Carthey, Jane

    2014-01-01

    Patients, clinicians and managers all want to be reassured that their healthcare organisation is safe. But there is no consensus about what we mean when we ask whether a healthcare organisation is safe or how this is achieved. In the UK, the measurement of harm, so important in the evolution of patient safety, has been neglected in favour of incident reporting. The use of softer intelligence for monitoring and anticipation of problems receives little mention in official policy. The Francis Inquiry report into patient treatment at the Mid Staffordshire NHS Foundation Trust set out 29 recommendations on measurement, more than on any other topic, and set the measurement of safety an absolute priority for healthcare organisations. The Berwick review found that most healthcare organisations at present have very little capacity to analyse, monitor or learn from safety and quality information. This paper summarises the findings of a more extensive report and proposes a framework which can guide clinical teams and healthcare organisations in the measurement and monitoring of safety and in reviewing progress against safety objectives. The framework has been used so far to promote self-reflection at both board and clinical team level, to stimulate an organisational check or analysis in the gaps of information and to promote discussion of ‘what could we do differently’. PMID:24764136

  4. Tannase production by Penicillium purpurogenum PAF6 in solid state fermentation of tannin-rich plant residues following OVAT and RSM.

    Science.gov (United States)

    Jana, Arijit; Maity, Chiranjit; Halder, Suman Kumar; Mondal, Keshab Chandra; Pati, Bikash Ranjan; Mohapatra, Pradeep Kumar Das

    2012-07-01

    Tannase production by newly isolated Penicillium purpurogenum PAF6 was investigated by 'one variable at a time' (OVAT) approach followed by response surface methodology (RSM). Tannin-rich plant residues were used as supporting solid substrate and sole carbon source and, among them, tamarind seed was found to be the most favorable substrate than haritaki, pomegranate, tea leaf waste and arjun fruit. Physicochemical parameters were initially optimized using OVAT methodology and some important factors like incubation time, incubation temperature, substrate:moisture ratio as well as carbon, nitrogen and phosphate concentrations were verified with Box-Behken design of response surface methodology. Phosphate source, nitrogen source and temperature were found as the most favorable variables in the maximization of production. Tannase production was enhanced from 1.536 U/g to 5.784 U/g using tamarind seed OVAT optimization and further enhancement up to 6.15 U/g following RSM. An overall 3.76- and 4.0-fold increases in tannase production were achieved in OVAT and RSM, respectively.

  5. Monitor for safety engineering facility

    International Nuclear Information System (INIS)

    Sato, Akira; Kaneda, Mitsunori.

    1982-01-01

    Purpose: To improve the reactor safety and decrease misoperation upon periodical inspection by instantly obtaining the judgement for the stand-by states in engineering safety facilities of a nuclear power plant. Constitution: Process inputs representing the states of valves, pumps, flowrates or the likes of the facility are gathered into an input device and inputted to a status monitor. The status of the facility inputted to the input device are judged for each of the inputs in a judging section and recognized as a present system stand-by pattern of the system (Valve) to be inspected. While on the other hand, a normal system stand-by pattern previously stored in a memory unit is read out by an instruction from an operator console and judged by comparison with the system stand-by pattern in a comparison section. The results are displayed on a display device. Upon periodical inspection, inspection procedures stored in the memory unit are displayed on the display device by the instruction from the operator console. (Seki, T.)

  6. Neural Net Safety Monitor Design

    Science.gov (United States)

    Larson, Richard R.

    2007-01-01

    The National Aeronautics and Space Administration (NASA) at the Dryden Flight Research Center (DFRC) has been conducting flight-test research using an F-15 aircraft (figure 1). This aircraft has been specially modified to interface a neural net (NN) controller as part of a single-string Airborne Research Test System (ARTS) computer with the existing quad-redundant flight control system (FCC) shown in figure 2. The NN commands are passed to FCC channels 2 and 4 and are cross channel data linked (CCDL) to the other computers as shown. Numerous types of fault-detection monitors exist in the FCC when the NN mode is engaged; these monitors would cause an automatic disengagement of the NN in the event of a triggering fault. Unfortunately, these monitors still may not prevent a possible NN hard-over command from coming through to the control laws. Therefore, an additional and unique safety monitor was designed for a single-string source that allows authority at maximum actuator rates but protects the pilot and structural loads against excessive g-limits in the case of a NN hard-over command input. This additional monitor resides in the FCCs and is executed before the control laws are computed. This presentation describes a floating limiter (FL) concept1 that was developed and successfully test-flown for this program (figure 3). The FL computes the rate of change of the NN commands that are input to the FCC from the ARTS. A window is created with upper and lower boundaries, which is constantly floating and trying to stay centered as the NN command rates are changing. The limiter works by only allowing the window to move at a much slower rate than those of the NN commands. Anywhere within the window, however, full rates are allowed. If a rate persists in one direction, it will eventually hit the boundary and be rate-limited to the floating limiter rate. When this happens, a persistent counter begins and after a limit is reached, a NN disengage command is generated. The

  7. Indicators to monitor NPP operational safety performance

    International Nuclear Information System (INIS)

    Gomez-Cobo, Ana

    2002-01-01

    Since December 1995 the IAEA activities on safety performance indicators focused on the elaboration of a framework for the establishment of an operational safety performance indicator programme. The development of this framework began with the consideration of the concept of NPP operational safety performance and the identification of operational safety attributes. For each operational safety attribute, overall indicators, envisioned as providing an overall evaluation of relevant aspects of safety performance, were established. Associated with each overall indicator is a level of strategic indicators intended to provide a bridge from overall to specific indicators. Finally each strategic indicator was supported by a set of specific indicators, which represent quantifiable measures of performance. The programme development was enhanced by pilot plant studies, conducted over a 15 month period from January 1998 to March 1999. The result of all this work is compiled in the IAEA-TECDOC-1141, to be published shortly. This paper presents a summary of this IAEA TECDOC. It describes the operational safety performance indicator framework proposed and discusses the results of and lessons learned from the pilot studies. Despite the efforts described, it is clear that additional research is still necessary in areas such as plant-specific adaptation of proposed frameworks in order to suit individual data collection systems and plant characteristics, indicator selection, indicator definition, goal setting, action thresholds, analysis of trends, indicator display systems, analysis of overall safety performance (i.e., aggregation or combination of indicators), safety culture indicators, qualitative indicators, and use of additional indicators to address issues such as industrial safety attitude and performance, staff welfare, and environmental compliance. This is the rationale for a new IAEA Coordinated Research Project on 'Development and application of indicators to monitor NPP

  8. Selection of indicators for continuous monitoring of patient safety: recommendations of the project 'safety improvement for patients in Europe'

    DEFF Research Database (Denmark)

    Kristensen, Solvejg; Mainz, Jan; Bartels, Paul

    2009-01-01

    such as culture, infections, surgical complications, medication errors, obstetrics, falls and specific diagnostic areas. CONCLUSION: The patient safety indicators recommended present a set of possible measures of patient safety. One of the future perspectives of implementing patient safety indicators...... for systematic monitoring is that it will be possible to continuously estimate the prevalence and incidence of patient safety quality problems. The lesson learnt from quality improvement is that it will pay off in terms of improving patient safety....

  9. Monitoring work zone safety and mobility impacts in Texas.

    Science.gov (United States)

    2009-05-01

    In this report, Texas Transportation Institute researchers identify key work zone safety and mobility : performance measures that the Texas Department of Transportation (TxDOT) should target as part of a work : zone monitoring program within a distri...

  10. Internet of Things Based Combustible Ice Safety Monitoring System Framework

    Science.gov (United States)

    Sun, Enji

    2017-05-01

    As the development of human society, more energy is requires to meet the need of human daily lives. New energies play a significant role in solving the problems of serious environmental pollution and resources exhaustion in the present world. Combustible ice is essentially frozen natural gas, which can literally be lit on fire bringing a whole new meaning to fire and ice with less pollutant. This paper analysed the advantages and risks on the uses of combustible ice. By compare to other kinds of alternative energies, the advantages of the uses of combustible ice were concluded. The combustible ice basic physical characters and safety risks were analysed. The developments troubles and key utilizations of combustible ice were predicted in the end. A real-time safety monitoring system framework based on the internet of things (IOT) was built to be applied in the future mining, which provide a brand new way to monitoring the combustible ice mining safety.

  11. Simultaneous sequential monitoring of efficacy and safety led to masking of effects.

    Science.gov (United States)

    van Eekelen, Rik; de Hoop, Esther; van der Tweel, Ingeborg

    2016-08-01

    Usually, sequential designs for clinical trials are applied on the primary (=efficacy) outcome. In practice, other outcomes (e.g., safety) will also be monitored and influence the decision whether to stop a trial early. Implications of simultaneous monitoring on trial decision making are yet unclear. This study examines what happens to the type I error, power, and required sample sizes when one efficacy outcome and one correlated safety outcome are monitored simultaneously using sequential designs. We conducted a simulation study in the framework of a two-arm parallel clinical trial. Interim analyses on two outcomes were performed independently and simultaneously on the same data sets using four sequential monitoring designs, including O'Brien-Fleming and Triangular Test boundaries. Simulations differed in values for correlations and true effect sizes. When an effect was present in both outcomes, competition was introduced, which decreased power (e.g., from 80% to 60%). Futility boundaries for the efficacy outcome reduced overall type I errors as well as power for the safety outcome. Monitoring two correlated outcomes, given that both are essential for early trial termination, leads to masking of true effects. Careful consideration of scenarios must be taken into account when designing sequential trials. Simulation results can help guide trial design. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. The PM-Assisted Reluctance Synchronous Starter/Generator (PM-RSM): Generator Experimental Characterization

    DEFF Research Database (Denmark)

    Pitic, Cristian Ilie; Tutelea, Lucian; Boldea, Ion

    2004-01-01

    and the parameters of the machine have to be known precisely. The present paper introduces a series of the tests for parameters and efficiency determination of a PM-assisted RSM in the generator mode. The testing methods consist of standstill tests (dc decay), generator no load testing with capacitor and on load ac...... and diode-rectifier dc tests. Satisfactory results are obtained but some unresolved questions are also raised....

  13. [Safety monitoring of cell-based medicinal products (CBMPs)].

    Science.gov (United States)

    Funk, Markus B; Frech, Marion; Spranger, Robert; Keller-Stanislawski, Brigitte

    2015-11-01

    Cell-based medicinal products (CBMPs), a category of advanced-therapy medicinal products (ATMPs), are authorised for the European market by the European Commission by means of the centralized marketing authorisation. By conforming to the German Medicinal Products Act (Sec. 4b AMG), national authorisation can be granted by the Paul-Ehrlich-Institut in Germany exclusively for ATMPs not based on a routine manufacturing procedure. In both procedures, quality, efficacy, and safety are evaluated and the risk-benefit balance is assessed. For the centralised procedure, mainly controlled clinical trial data must be submitted, whereas the requirements for national procedures could be modified corresponding to the stage of development of the ATMP. After marketing authorization, the marketing authorization/license holder is obligated to report all serious adverse reactions to the competent authority and to provide periodic safety update reports. If necessary, post-authorization safety studies could be imposed. On the basis of these regulatory measures, the safety of advanced therapies can be monitored and improved.

  14. Artificial neural network for research reactor safety status monitoring

    International Nuclear Information System (INIS)

    Varde, P.V.

    2001-01-01

    During reactor upset/abnormal conditions, emphasis is placed on plant operator's ability to quickly identify the problem and perform diagnosis and initiate recovery action to ensure safety of the plant. However, the reliability of human action is adversely affected at the time of crisis, due to the time stress and psychological factors. Availability of operational aids capable of monitoring the status of the plant and quickly identifying the deviation from normal operation is expected to significantly improve the operator reliability. Artificial Neural Network (based on Back Propagation Algorithm) has been developed and applied for reactor safety status monitoring, as part of an Operator Support System. ANN has been trained for 14 different plant states using 42 input symptom patterns. Recall tests performed on the ANN show that the system was able to identify the plant state with reasonable accuracy. (author)

  15. Indicators to monitor NPP safety performance. Working material

    International Nuclear Information System (INIS)

    1997-01-01

    Numerical indicators to monitor safety status and overall safety performance of nuclear power plants (NPPs) are used by operators and some regulators worldwide. During the last few years, the IAEA, through Technical Committee Meetings and Consultants' Meetings has worked on this area. This report presents a framework for nuclear power plant safety performance indicators that was developed during two consultant meetings held at the IAEA headquarters in Vienna in December 1995 and November 1996. Annex 2 on risk based indicators was prepared during a consultants' meeting held in Vienna in July 1996. An additional outcome from these activities, was the recommendation that the IAEA conduce pilot exercises at several nuclear power plants that might be interested to participate, in order to test the validity of the concept and its usefulness. 6 figs

  16. Indicators for monitoring of safety operation and condition of nuclear power stations

    International Nuclear Information System (INIS)

    Manova, D.

    2001-01-01

    A common goal of all employees in the nuclear power field is safety operation of nuclear power stations. The evaluation and control of NPP safety operation are a part of the elements of safety management. The present report is related only to a part of the total assessment and control of the plant safety operation, namely - the indicator system for monitoring of Kozloduy NPP operation and condition. (author)

  17. A Novel Series Connected Batteries State of High Voltage Safety Monitor System for Electric Vehicle Application

    Directory of Open Access Journals (Sweden)

    Qiang Jiaxi

    2013-01-01

    Full Text Available Batteries, as the main or assistant power source of EV (Electric Vehicle, are usually connected in series with high voltage to improve the drivability and energy efficiency. Today, more and more batteries are connected in series with high voltage, if there is any fault in high voltage system (HVS, the consequence is serious and dangerous. Therefore, it is necessary to monitor the electric parameters of HVS to ensure the high voltage safety and protect personal safety. In this study, a high voltage safety monitor system is developed to solve this critical issue. Four key electric parameters including precharge, contact resistance, insulation resistance, and remaining capacity are monitored and analyzed based on the equivalent models presented in this study. The high voltage safety controller which integrates the equivalent models and control strategy is developed. By the help of hardware-in-loop system, the equivalent models integrated in the high voltage safety controller are validated, and the online electric parameters monitor strategy is analyzed and discussed. The test results indicate that the high voltage safety monitor system designed in this paper is suitable for EV application.

  18. A novel series connected batteries state of high voltage safety monitor system for electric vehicle application.

    Science.gov (United States)

    Jiaxi, Qiang; Lin, Yang; Jianhui, He; Qisheng, Zhou

    2013-01-01

    Batteries, as the main or assistant power source of EV (Electric Vehicle), are usually connected in series with high voltage to improve the drivability and energy efficiency. Today, more and more batteries are connected in series with high voltage, if there is any fault in high voltage system (HVS), the consequence is serious and dangerous. Therefore, it is necessary to monitor the electric parameters of HVS to ensure the high voltage safety and protect personal safety. In this study, a high voltage safety monitor system is developed to solve this critical issue. Four key electric parameters including precharge, contact resistance, insulation resistance, and remaining capacity are monitored and analyzed based on the equivalent models presented in this study. The high voltage safety controller which integrates the equivalent models and control strategy is developed. By the help of hardware-in-loop system, the equivalent models integrated in the high voltage safety controller are validated, and the online electric parameters monitor strategy is analyzed and discussed. The test results indicate that the high voltage safety monitor system designed in this paper is suitable for EV application.

  19. Understanding of safety monitoring in clinical trials by individuals with CF or their parents: A qualitative analysis.

    Science.gov (United States)

    Kern-Goldberger, Andrew S; Hessels, Amanda J; Saiman, Lisa; Quittell, Lynne M

    2018-03-14

    Recruiting both pediatric and adult participants for clinical trials in CF is currently of paramount importance as numerous new therapies are being developed. However, recruitment is challenging as parents of children with CF and adults with CF cite safety concerns as a principal barrier to enrollment. In conjunction with the CF Foundation (CFF) Data Safety Monitoring Board (DSMB), a pilot brochure was developed to inform patients and parents of the multiple levels of safety monitoring; the CFF simultaneously created an infographic representing the safety monitoring process. This study explores the attitudes and beliefs of CF patients and families regarding safety monitoring and clinical trial participation, and elicits feedback regarding the educational materials. Semi-structured interviews were conducted using a pre-tested interview guide and audio-recorded during routine CF clinic visits. Participants included 5 parents of children with CF quotations: attitudes toward clinical trials, safety values, conceptualizing the safety monitoring process, and priorities for delivery of patient education. Participant feedback was used to revise the pilot brochure; text was shortened, unfamiliar words clarified (e.g., "pipeline"), abbreviations eliminated, and redundancy avoided. Qualitative analysis of CF patient and family interviews provided insights into barriers to participation in clinical trials, safety concerns, perspectives on safety monitoring and educational priorities. We plan a multicenter study to determine if the revised brochure reduces knowledge, attitude and practice barriers regarding participation in CF clinical trials. Copyright © 2018 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.

  20. Multidisciplinary training program to create new breed of radiation monitor: the health and safety technician

    International Nuclear Information System (INIS)

    Vance, W.F.

    1979-01-01

    A multidiscipline training program established to create a new monitor, theHealth and Safety Technician, is described. The training program includes instruction in fire safety, explosives safety, industrial hygiene, industrial safety, health physics, and general safety practices

  1. An Overview of the NASA Aviation Safety Program Propulsion Health Monitoring Element

    Science.gov (United States)

    Simon, Donald L.

    2000-01-01

    The NASA Aviation Safety Program (AvSP) has been initiated with aggressive goals to reduce the civil aviation accident rate, To meet these goals, several technology investment areas have been identified including a sub-element in propulsion health monitoring (PHM). Specific AvSP PHM objectives are to develop and validate propulsion system health monitoring technologies designed to prevent engine malfunctions from occurring in flight, and to mitigate detrimental effects in the event an in-flight malfunction does occur. A review of available propulsion system safety information was conducted to help prioritize PHM areas to focus on under the AvSP. It is noted that when a propulsion malfunction is involved in an aviation accident or incident, it is often a contributing factor rather than the sole cause for the event. Challenging aspects of the development and implementation of PHM technology such as cost, weight, robustness, and reliability are discussed. Specific technology plans are overviewed including vibration diagnostics, model-based controls and diagnostics, advanced instrumentation, and general aviation propulsion system health monitoring technology. Propulsion system health monitoring, in addition to engine design, inspection, maintenance, and pilot training and awareness, is intrinsic to enhancing aviation propulsion system safety.

  2. Assessing the impact of safety monitoring on the efficacy analysis in large Phase III group sequential trials with non-trivial safety event rate.

    Science.gov (United States)

    Weng, Yanqiu; Palesch, Yuko Y; DeSantis, Stacia M; Zhao, Wenle

    2016-01-01

    In Phase III clinical trials for life-threatening conditions, some serious but expected adverse events, such as early deaths or congestive heart failure, are often treated as the secondary or co-primary endpoint, and are closely monitored by the Data and Safety Monitoring Committee (DSMC). A naïve group sequential design (GSD) for such a study is to specify univariate statistical boundaries for the efficacy and safety endpoints separately, and then implement the two boundaries during the study, even though the two endpoints are typically correlated. One problem with this naïve design, which has been noted in the statistical literature, is the potential loss of power. In this article, we develop an analytical tool to evaluate this negative impact for trials with non-trivial safety event rates, particularly when the safety monitoring is informal. Using a bivariate binary power function for the GSD with a random-effect component to account for subjective decision-making in safety monitoring, we demonstrate how, under common conditions, the power loss in the naïve design can be substantial. This tool may be helpful to entities such as the DSMCs when they wish to deviate from the prespecified stopping boundaries based on safety measures.

  3. Regulatory Network Controlling Extracellular Proteins in Erwinia carotovora subsp. carotovora: FlhDC, the Master Regulator of Flagellar Genes, Activates rsmB Regulatory RNA Production by Affecting gacA and hexA (lrhA) Expression▿

    OpenAIRE

    Cui, Yaya; Chatterjee, Asita; Yang, Hailian; Chatterjee, Arun K.

    2008-01-01

    Erwinia carotovora subsp. carotovora produces an array of extracellular proteins (i.e., exoproteins), including plant cell wall-degrading enzymes and Harpin, an effector responsible for eliciting hypersensitive reaction. Exoprotein genes are coregulated by the quorum-sensing signal, N-acyl homoserine lactone, plant signals, an assortment of transcriptional factors/regulators (GacS/A, ExpR1, ExpR2, KdgR, RpoS, HexA, and RsmC) and posttranscriptional regulators (RsmA, rsmB RNA). rsmB RNA produc...

  4. Development of radiation safety monitoring system at gamma greenhouse gamma facility

    International Nuclear Information System (INIS)

    Hairul Nizam Idris; Azimawati Ahmad, Ahmad Zaki Hussain; Ahmad Fairuz Mohd Nasir

    2009-01-01

    This paper is discussing about installation of radiation safety monitoring system at Gamma Greenhouse Gamma facility, Agrotechnology and Bioscience Division (BAB). This facility actually is an outdoor type irradiation facility, which first in Nuclear Malaysia and the only one in Malaysia. Source Cs-137 (801 Curie) was use as radiation source and it located at the centre of 30 metres diameter size of open irradiation area. The radiation measurement and monitoring system to be equipped in this facility were required the proper equipment and devices, specially purpose for application at outside of building. Research review, literature study and discussion with the equipment manufacturers was being carried out, in effort to identify the best system should be developed. Factors such as tropical climate, environment surrounding and security were considered during selecting the proper system. Since this facility involving with panoramic radiation type, several critical and strategic locations have been fixed with radiation detectors, up to the distance at 200 meter from the radiation source. Apart from that, this developed system also was built for capable to provide the online real-time reading (using internet). In general, it can be summarized that the radiation safety monitoring system for outdoor type irradiation facility was found much different and complex compared to the system for indoor type facility. Keyword: radiation monitoring, radiation safety, Gamma Greenhouse, outdoor irradiation facility, panoramic radiation. (Author)

  5. BARC-risk monitor- a tool for operational safety assessment in nuclear power plants

    International Nuclear Information System (INIS)

    Vinod, Gopika; Saraf, R.K.; Babar, A.K.; Hadap, Nikhil

    2000-12-01

    Probabilistic safety assessment has become a key tool as on today to identify and understand nuclear power plant vulnerabilities. As a result of the availability of these PSA studies, there is a desire to use them to enhance plant safety and to operate the nuclear stations in the most efficient manner. Risk monitor is a PC based tool, which computes the real time safety level and assists plant personnel to manage day-to-day activities. Risk monitor is a PC based user friendly software tool used for modification and re-analysis of a nuclear power plant. Operation of risk monitor is based on PSA methods for assisting in day to day applications. Risk monitoring programs can assess the risk profile and are used to optimise the operation of nuclear power plants with respect to a minimum risk level over the operating time. This report presents the background activities of risk monitor, its application areas and also gives the status of such tools in international scenarios. The software is based on the PSA model of Kaiga generating station and would be applicable to similar design configuration. (author)

  6. Reactivity monitoring for safety purposes on the UK prototype fast reactor

    International Nuclear Information System (INIS)

    Lord, D.J.; Wilkes, D.J.

    1987-01-01

    The small size and high rating of the liquid metal cooled fast breeder reactor (LMFBR) make the provision of safety related instrumentation for individual subassemblies both difficult and expensive. Global monitoring of the core is thus very attractive. Reactivity monitoring is an important part of such global monitoring. Reactivity monitoring on a short timescale (a few seconds) is used on the UK Prototype Fast Reactor (PFR) as a trip parameter and long-term reactivity monitoring is being developed as a means of providing early warning of slowly developing faults. Results are presented from PFR to demonstrate the capabilities of reactivity monitoring in an operational fast reactor power station. (author)

  7. Tools for road infrastructure safety management in poland

    Directory of Open Access Journals (Sweden)

    Kustra Wojciech

    2017-01-01

    Full Text Available Road safety can be improved by implementing principles of road safety infrastructure management (RIS on the network of European roads as adopted in the Directive. The document recommends that member states should use tried and tested tools for road safety management such as: road safety impact assessment (RIA, road safety audit (RSA, safety management on existing road networks including road safety ranking (RSM and road safety inspection (RSI. The objective of the methods is to help road authorities to take rational decisions in the area of road safety and road infrastructure safety and understand the consequences occurring in the particular phases of road life cycle. To help with assessing the impact of a road project on the safety of related roads, a method was developed for long-term forecasts of accidents and accident cost estimation as well as a risk classification to identify risks that are not acceptable risks. With regard to road safety audits and road safety inspection, a set of principles was developed to identify risks and the basic classification of mistakes and omissions.

  8. Monitoring antimalarial safety and tolerability in clinical trials: A case study from Uganda

    Directory of Open Access Journals (Sweden)

    Mpimbaza Arthur

    2008-06-01

    Full Text Available Abstract Background New antimalarial regimens, including artemisinin-based combination therapies (ACTs, have been adopted widely as first-line treatment for uncomplicated malaria. Although these drugs appear to be safe and well-tolerated, experience with their use in Africa is limited and continued assessment of safety is a priority. However, no standardized guidelines for evaluating drug safety and tolerability in malaria studies exist. A system for monitoring adverse events in antimalarial trials conducted in Uganda was developed. Here the reporting system is described, and difficulties faced in analysing and interpreting the safety results are illustrated, using data from the trials. Case description Between 2002 and 2007, eleven randomized, controlled clinical trials were conducted to compare the efficacy, safety, and tolerability of different antimalarial regimens for treatment of uncomplicated malaria in Uganda. The approach to adverse event monitoring was similar in all studies. A total of 5,614 treatments were evaluated in 4,876 patients. Differences in baseline characteristics and patterns of adverse event reporting were noted between the sites, which limited the ability to pool and analyse data. Clinical failure following antimalarial treatment confounded associations between treatment and adverse events that were also common symptoms of malaria, particularly in areas of lower transmission intensity. Discussion and evaluation Despite prospectively evaluating for adverse events, limitations in the monitoring system were identified. New standardized guidelines for monitoring safety and tolerability in antimalarial trials are needed, which should address how to detect events of greatest importance, including serious events, those with a causal relationship to the treatment, those which impact on adherence, and events not previously reported. Conclusion Although the World Health Organization has supported the development of

  9. Warpage analysis on thin shell part using response surface methodology (RSM)

    Science.gov (United States)

    Zulhasif, Z.; Shayfull, Z.; Nasir, S. M.; Fathullah, M.; Hazwan, M. H. M.

    2017-09-01

    The optimisation of moulding parameters appropriate to reduce warpage defects produce using Autodesk Moldflow Insight (AMI) 2012 software The product is injected by using Acrylonitrile-Butadiene-Styrene (ABS) materials. This analysis has processing parameter that varies in melting temperature, mould temperature, packing pressure and packing time. Design of Experiments (DOE) has been integrated to obtain a polynomial model using Response Surface Methodology (RSM). The Glowworm Swarm Optimisation (GSO) method is used to predict a best combination parameters to minimise warpage defect in order to produce high quality parts.

  10. Safety regulations regarding to accident monitoring and accident sampling at Russian NPPs with VVER type reactors

    International Nuclear Information System (INIS)

    Sharafutdinov, Rachet; Lankin, Michail; Kharitonova, Nataliya

    2014-01-01

    The paper describes a tendency by development of regulatory document requirements related to accident monitoring and accident sampling at Russia's NPPs. Lessons learned from the Fukushima Daiichi accident pointed at the importance and necessary to carry out an additional safety check at Russia's nuclear power plants in the preparedness for management of severe accidents at NPPs. Planned measures for improvement of severe accidents management include development and implementation of the accident instrumentation systems, providing, monitoring, management and storage of information in a severe accident conditions. The draft of Safety Guidelines <monitoring system of nuclear power plants with VVER reactors' prepared by Scientific and Engineering Centre for Nuclear and Radiation Safety (SEC NRS) established the main criteria for accident monitoring instrumentation that can monitor relevant plant parameters in the reactor and inside containment during and after a severe accident in nuclear power plants. Development of these safety guidelines is in line with the recommendations of IAEA Action Plan on Nuclear Safety in response to the Fukushima Daiichi event and recommendations of the IAEA Nuclear Energy series Report <Monitoring Systems for Nuclear Power Plants' (Draft V 2.7). The paper presents the principles, which are used as the basis for selection of plant parameters for accident monitoring and for establishing of accident monitoring instrumentation. The recommendations to the accident sampling system capable to obtain the representative reactor coolant and containment air and fluid samples that support accurate analytical results for the parameters of interest are considered. The radiological and chemistry parameters to be monitored for primary coolant and sump and for containment air are specified. (author)

  11. Concept for creating program-technical complex of safety monitoring with system of safety parameters presentation functions on the basis of routine WWER-1000 systems

    International Nuclear Information System (INIS)

    Dunaev, V.G.; Tarasov, M. V.; Povarov, P.V.

    2005-01-01

    Prerequisites of creating the software-hardware complex for reactor safety monitoring on the Volgodonsk NPP are analyzed and generalized. The concept of this complex is based on functions of the safety parameters presentation system. It will serve as an interface between operator and technological process and give to operator a possibility to estimate quickly the state of the safety of the nuclear power unit. The complex will be created on the basis of routine reactor monitoring and control systems intended for the WWER-1000 reactor. In addition to existing soft- and hard-wares for reactor monitoring and for analysis of technological archive, it is proposed to create and connect in parallel the new software-hardware complex which ensures calculation and presentation of generalized factors of reactor safety [ru

  12. Monitoring consumer confidence in food safety: an exploratory study

    NARCIS (Netherlands)

    Jonge, de J.; Frewer, L.J.; Trijp, van J.C.M.; Renes, R.J.; Wit, de W.; Timmers, J.C.M.

    2004-01-01

    Abstract: In response to the potential for negative economic and societal effects resulting from a low level of consumer confidence in food safety, it is important to know how confidence is potentially influenced by external events. The aim of this article is to describe the development of a monitor

  13. Uncertain added value of Global Trigger Tool for monitoring of patient safety in cancer care

    DEFF Research Database (Denmark)

    Lipczak, Henriette; Neckelmann, Kirsten; Steding-Jessen, Marianne

    2011-01-01

    Monitoring patient safety is a challenging task. The lack of a golden standard has contributed to the recommendation and introduction of several methods. In 2000 the Danish Lung Cancer Registry (DLCR) was established to monitor the clinical management of lung cancer. In 2008 the Global Trigger Tool...... (GTT) was recommended in Denmark as a tool for the monitoring of patient safety. Ideally, the recommendation of a new tool should be preceded by a critical assessment of its added value....

  14. Design of safety monitor system for operation sintering furnace ME-06

    International Nuclear Information System (INIS)

    Sugeng Rianto; Triarjo; Djoko Kisworo; Agus Sartono

    2013-01-01

    Design of safety monitoring system for safety operation of sinter furnace ME-06 has been done. Parameters monitored during this operation include: temperature, gas pressure, flow rate of gas, voltage and current furnace. For sintering furnace temperature system that monitored were the temperature of the furnace temperature, the temperature of the cooling water system inlet and outlet, temperature of flow hydrogen gas inlet and outlet. For pressure system and flow rate gas sinter furnace which monitored the pressure and flow rate of hydrogen gas inlet and outlet. The system also monitors current and voltage applied to the sinter furnace heating system. Monitor system hardware consists of: the system temperature sensor, pressure, rate and data acquisition systems. While software systems using the labview driver interface that connects the hard and software systems. Function test results during sintering operation for setting the temperature 1700 °C sintering temperature increases the ramp function by 250 °C/hour average measurements obtained when the sintering time 1707.016 °C with a standard deviation of 0.38 °C. The maximum temperature of the hydrogen gas temperature 35.4 °C. The maximum temperature of the cooling water system 27.4 °C. The maximum pressure of 1,911 bar Gas Inlet and outlet of 0,051 bar. Maximum inlet gas flow 12.996 L / min and outlet 14.086 L / min. (author)

  15. Pharmacist medication reviews to improve safety monitoring in primary care patients.

    Science.gov (United States)

    Gallimore, Casey E; Sokhal, Dimmy; Zeidler Schreiter, Elizabeth; Margolis, Amanda R

    2016-06-01

    Patients prescribed psychotropic medications within primary care are at risk of suboptimal monitoring. It is unknown whether pharmacists can improve medication safety through targeted monitoring of at risk populations. Access Community Health Centers implemented a quality improvement pilot project that included pharmacists on an integrated care team to provide medication reviews for patients. Aims were to determine whether inclusion of a pharmacist performing medication reviews within a primary care behavioral health (PCBH) practice is feasible and facilitates safe medication use. Pharmacists performed medication reviews of the electronic health record for patients referred for psychiatry consultation. Reviews were performed 1-3 months following consultation and focused on medications with known suboptimal monitoring rates. Reviews were documented within the EHR and routed to the primary care provider. Primary outcome measures were change in percentage up-to-date on monitoring and AIMS assessment, and at risk of experiencing drug interaction(s) between baseline and 3 months postreview. Secondary outcome was provider opinion of medication reviews collected via electronic survey. Reviews were performed for 144 patients. Three months postreview, percentage up-to-date on recommended monitoring increased 18% (p = .0001), at risk for drug interaction decreased 20% (p improved safety monitoring of psychotropic medications. Results identify key areas for improvement that other clinics considering integration of similar pharmacy services should consider. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  16. Modeling and optimization of Fischer-Tropsch synthesis over Co-Mn-Ce/SiO_2 catalyst using hybrid RSM/LHHW approaches

    International Nuclear Information System (INIS)

    Zohdi-Fasaei, Hossein; Atashi, Hossein; Farshchi Tabrizi, Farshad; Mirzaei, Ali Akbar

    2017-01-01

    Operating conditions considerably affect the energy required for Fischer-Tropsch synthesis, depending on the catalyst composition and reactor type (catalyst system). This paper reports the use of cobalt-manganese-cerium supported on silica as a novel CO hydrogenation catalyst, to produce hydrocarbons in a fixed bed micro-reactor. Response surface methodology (RSM) was applied to study the effects of temperature, pressure, feed ratio and their interactions on CO consumption rate, and the selectivity of light olefins (light olefinity), methane and C_5_+ hydrocarbons. Quadratic mathematical models adequately described the responses in this catalyst system. According to Langmuir Hinshelwood Hougen Watson (LHHW) approach, kinetic mechanism of the reaction was found to be an associative adsorption of H_2 and CO. Statistical analysis demonstrated that pressure and feed ratio were the most important factors for the production of C_5_+ and light alkenes, respectively. Model graphs indicated that minimum methane selectivity was achieved at 523.15 k and 2 bar. The maximum amounts of light olefins and heavier hydrocarbons were obtained at H_2/CO = 1 and H_2/CO = 2, respectively. Characterization of precursor and calcined catalyst (before and after the reaction) was carried out using SEM and BET techniques. - Highlights: • The performance of a new catalytic system was studied using RSM as a research plan. • Interactions between significant factors were investigated using mathematical models. • Based on LHHW approach, kinetic mechanism was molecular adsorptions of H_2 and CO. • RSM rate expression was in consistent with the LHHW kinetic model. • Hybrid RSM/LHHW is promising for optimization, mechanism and selectivity studies.

  17. Guidance on the implementation of a risk based safety performance monitoring system for nuclear power plants

    International Nuclear Information System (INIS)

    Sewell, R.T.; Kuritzky, A.S.; Khatib-Rahbar, M.

    1997-05-01

    The principal objective of the present study is to review and evaluate existing Performance Indicator (PI) monitoring programs, and to develop and demonstrate an overall PSA-based methodology and framework for the monitoring and use of risk-based PIs and SIs (Safety Indicator), that would enable: Identification of trends and patterns in safety performance at a specific plant and a population of plants; Assessment of the significance of the trends and patterns; Identification of precursors of accident sequences and safety reductions; Identification of the most critical functional areas of concern, especially as they relate to a defense-in-depth safety philosophy; Comparison of safety performance trends at a plant with those at comparable plants; Incorporation of the PIs and SIs into a risk- and performance-based decision process. To support the overall project objective, it is important that information needs and data collection procedures are clearly outlined. Of key significance in this regard is the premise that a performance monitoring system should not be burdened by an excessive number of low-level PIs that may have only a peripheral relationship to safety. Other supporting objectives of the study include: To identify and discuss other issues pertaining to the practical implementation of a safety performance monitoring system (outlining the databases and algorithms needed); and to demonstrate implementation of the preliminary guidance for monitoring and use of the selected set of PIs and SIs, within the proposed framework, via application to the operating history of a NPP having a PSA and readily available event data

  18. Monitoring road safety development at regional level: A case study in the ASEAN region.

    Science.gov (United States)

    Chen, Faan; Wang, Jianjun; Wu, Jiaorong; Chen, Xiaohong; Zegras, P Christopher

    2017-09-01

    Persistent monitoring of progress, evaluating the results of interventions and recalibrating to achieve continuous improvement over time is widely recognized as being crucial towards the successful development of road safety. In the ASEAN (Association of Southeast Asian Nations) region there is a lack of well-resourced teams that contain multidisciplinary safety professionals, and specialists in individual countries, who are able to carry out this work effectively. In this context, not only must the monitoring framework be effective, it must also be easy to use and adapt. This paper provides a case study that can be easily reproduced; based on an updated and refined Road Safety Development Index (RSDI), by means of the RSR (Rank-sum ratio)-based model, for monitoring/reporting road safety development at regional level. The case study was focused on the road safety achievements in eleven Southeast Asian countries; identifying the areas of poor performance, potential problems and delays. These countries are finally grouped into several classes based on an overview of their progress and achievements regarding to road safety. The results allow the policymakers to better understand their own road safety progress toward their desired impact; more importantly, these results enable necessary interventions to be made in a quick and timely manner. Keeping action plans on schedule if things are not progressing as desired. This would avoid 'reinventing the wheel' and trial and error approaches to road safety, making the implementation of action plans more effective. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Comparative study on the predictability of statistical models (RSM and ANN) on the behavior of optimized buccoadhesive wafers containing Loratadine and their in vivo assessment.

    Science.gov (United States)

    Chakraborty, Prithviraj; Parcha, Versha; Chakraborty, Debarupa D; Ghosh, Amitava

    2016-01-01

    Buccoadhesive wafer dosage form containing Loratadine is formulated utilizing Formulation by Design (FbD) approach incorporating sodium alginate and lactose monohydrate as independent variable employing solvent casting method. The wafers were statistically optimized using Response Surface Methodology (RSM) and Artificial Neural Network algorithm (ANN) for predicting physicochemical and physico-mechanical properties of the wafers as responses. Morphologically wafers were tested using SEM. Quick disintegration of the samples was examined employing Optical Contact Angle (OCA). The comparison of the predictability of RSM and ANN showed a high prognostic capacity of RSM model over ANN model in forecasting mechanical and physicochemical properties of the wafers. The in vivo assessment of the optimized buccoadhesive wafer exhibits marked increase in bioavailability justifying the administration of Loratadine through buccal route, bypassing hepatic first pass metabolism.

  20. A Study on the Estimation Method of Risk Based Area for Jetty Safety Monitoring

    Directory of Open Access Journals (Sweden)

    Byeong-Wook Nam

    2015-09-01

    Full Text Available Recently, the importance of safety-monitoring systems was highlighted by the unprecedented collision between a ship and a jetty in Yeosu. Accordingly, in this study, we introduce the concept of risk based area and develop a methodology for a jetty safety-monitoring system. By calculating the risk based areas for a ship and a jetty, the risk of collision was evaluated. To calculate the risk based areas, we employed an automatic identification system for the ship, stopping-distance equations, and the regulation velocity near the jetty. In this paper, we suggest a risk calculation method for jetty safety monitoring that can determine the collision probability in real time and predict collisions using the amount of overlap between the two calculated risk based areas. A test was conducted at a jetty control center at GS Caltex, and the effectiveness of the proposed risk calculation method was verified. The method is currently applied to the jetty-monitoring system at GS Caltex in Yeosu for the prevention of collisions.

  1. 49 CFR 385.333 - What happens at the end of the 18-month safety monitoring period?

    Science.gov (United States)

    2010-10-01

    ... SAFETY REGULATIONS SAFETY FITNESS PROCEDURES New Entrant Safety Assurance Program § 385.333 What happens at the end of the 18-month safety monitoring period? (a) If a safety audit has been performed within... the same basis as any other carrier. (d) If a safety audit or compliance review has not been performed...

  2. Safety KPIs - Monitoring of safety performance

    Directory of Open Access Journals (Sweden)

    Andrej Lališ

    2014-09-01

    Full Text Available This paper aims to provide brief overview of aviation safety development focusing on modern trends represented by implementation of Safety Key Performance Indicators. Even though aviation is perceived as safe means of transport, it is still struggling with its complexity given by long-term growth and robustness which it has reached today. Thus nowadays safety issues are much more complex and harder to handle than ever before. We are more and more concerned about organizational factors and control mechanisms which have potential to further increase level of aviation safety. Within this paper we will not only introduce the concept of Key Performance Indicators in area of aviation safety as an efficient control mechanism, but also analyse available legislation and documentation. Finally we will propose complex set of indicators which could be applied to Czech Air Navigation Service Provider.

  3. Use of the Safety Monitor in operational decision-making at a nuclear generating facility

    International Nuclear Information System (INIS)

    Chien, Shan H.; Hook, Thomas G.; Lee, Roger J.

    1998-01-01

    The utilization of Safety Monitor at a nuclear generating facility in 1994 revolutionized the way US nuclear power plants manage configuration risks. At Southern California Edison (SCE) Company's San Onofre Nuclear Generating Station, it transformed probabilistic risk assessment (PRA) from a retrospective tool for understanding past risk into a prospective tool for controlling future risk. Since that time, many other nuclear utilities have taken aggressive steps in using PRA better to understand and manage risks associated with plant operation and maintenance. These utilities have employed a variety of methods ranging from systems similar to San Onofre's Safety Monitor to systems dramatically different in both technology and philosophy. In the development and use of its Safety Monitor, SCE has been guided by two philosophical goals: (1) maximize the objectivity of PRA-informed decision-making relative to managing configuration risks, and (2) ensure that risks are managed conservatively

  4. Radiological safety system based on real-time tritium-in-air monitoring indoors and in effluents

    International Nuclear Information System (INIS)

    Bidica, N.; Sofalca, N; Balteanu, O.; Srefan, I.

    2006-01-01

    Exposure to tritium is an important health hazard in any tritium processing facility so that implementing a real-time tritium monitoring system is necessary for its operation in safety conditions. The tritium processing facility operators need to be informed at any time about the in-air tritium concentration indoors or in the stack effluents, in order to detect immediately any leaks in tritium containments, or any releases inside the buildings or to the environment. This information is very important for adopting if necessary protection measures and correcting actions as quickly as possible. In this paper we describe an improved real-time tritium monitoring system designed for the Heavy Water Detritiation Pilot Plant of National Institute for Cryogenics and Isotopes Separation, Rm. Valcea, Romania. The design of the Radiological Safety System implemented for the ICIT Water Detritiation Pilot Plant is intended to provide the maximum safety level based on the ALARA concept. The main functions of tritium monitoring system are: - monitoring the working areas and gaseous effluents by determination of the tritium-in-air activity concentration; - local and remote data display; - assessing of environment dose equivalent rates and dose equivalents in the working environment (for personnel exposure control and work planning); - assessing the total tritium activity released to the environment through ventilation exhaust stack; - safety functions, i.e., local and remote, locking/unlocking personnel access, process shut-down in emergency conditions and start of the air cleaning systems. With all these features our tritium monitoring system is really a safety system adequate for personnel and environmental protection. (authors)

  5. Automatic crack detection and classification method for subway tunnel safety monitoring.

    Science.gov (United States)

    Zhang, Wenyu; Zhang, Zhenjiang; Qi, Dapeng; Liu, Yun

    2014-10-16

    Cracks are an important indicator reflecting the safety status of infrastructures. This paper presents an automatic crack detection and classification methodology for subway tunnel safety monitoring. With the application of high-speed complementary metal-oxide-semiconductor (CMOS) industrial cameras, the tunnel surface can be captured and stored in digital images. In a next step, the local dark regions with potential crack defects are segmented from the original gray-scale images by utilizing morphological image processing techniques and thresholding operations. In the feature extraction process, we present a distance histogram based shape descriptor that effectively describes the spatial shape difference between cracks and other irrelevant objects. Along with other features, the classification results successfully remove over 90% misidentified objects. Also, compared with the original gray-scale images, over 90% of the crack length is preserved in the last output binary images. The proposed approach was tested on the safety monitoring for Beijing Subway Line 1. The experimental results revealed the rules of parameter settings and also proved that the proposed approach is effective and efficient for automatic crack detection and classification.

  6. Automatic Crack Detection and Classification Method for Subway Tunnel Safety Monitoring

    Directory of Open Access Journals (Sweden)

    Wenyu Zhang

    2014-10-01

    Full Text Available Cracks are an important indicator reflecting the safety status of infrastructures. This paper presents an automatic crack detection and classification methodology for subway tunnel safety monitoring. With the application of high-speed complementary metal-oxide-semiconductor (CMOS industrial cameras, the tunnel surface can be captured and stored in digital images. In a next step, the local dark regions with potential crack defects are segmented from the original gray-scale images by utilizing morphological image processing techniques and thresholding operations. In the feature extraction process, we present a distance histogram based shape descriptor that effectively describes the spatial shape difference between cracks and other irrelevant objects. Along with other features, the classification results successfully remove over 90% misidentified objects. Also, compared with the original gray-scale images, over 90% of the crack length is preserved in the last output binary images. The proposed approach was tested on the safety monitoring for Beijing Subway Line 1. The experimental results revealed the rules of parameter settings and also proved that the proposed approach is effective and efficient for automatic crack detection and classification.

  7. Toward an integrated system concept for monitoring and evaluation of safety culture

    International Nuclear Information System (INIS)

    Makino, Maomi; Sakaue, Takeharu

    2004-01-01

    The concept of ''nuclear safety culture'' has been advocated and has been much discussed internationally by INSAG (The International Nuclear Safety Advisory Group) under IAEA (the International Atomic Energy Agency) and other institutions since Chernobyl accident. On the safety front, Japan had maintained an excellent track record in nuclear power operations throughout the 1990s. However, there have been a series of new type of problems strongly implying degradation of safety culture, e.g., Monju accident, fire and explosion accident at an Asphalt Solidification Process Facility at Tokai, falsification of annealing data at nuclear power plants (NPP), another data falsification for transport cask of spent fuel and JCO criticality accident. Then the TEPCO (Tokyo Electric Power Company) issue was revealed in 2002. Triggered by this issue, the Nuclear and Industrial Safety Agency (NISA) has been implementing a variety of improvements, one of which was the establishment of a study group in 2003, which invited experts from other fields as well as from nuclear-related industries, to study on how to implement safety culture sufficiently and possible recommendations. Subjects such as the followings piled in the study report will indicate leading keys in case it is going to realize such efforts: ''Foundation of safety culture is a quality management'' and ''Realistic and scientific technique is necessary for the evaluation of safety culture''. In order to respond to these requests, JNES have been advancing the development toward an Integrated System Concept for Monitoring and Evaluation of Safety Culture. This paper describes the outline of the study results reported by the study group and then introduces one of subsystems, SCEST, structuring the integrated system concept for Monitoring and Evaluation of Safety Culture. (author)

  8. The GacS/A-RsmA Signal Transduction Pathway Controls the Synthesis of Alkylresorcinol Lipids that Replace Membrane Phospholipids during Encystment of Azotobacter vinelandii SW136.

    Directory of Open Access Journals (Sweden)

    Yanet Romero

    Full Text Available Azotobacter vinelandii is a soil bacterium that undergoes a differentiation process that forms cysts resistant to desiccation. During encystment, a family of alkylresorcinols lipids (ARs are synthesized and become part of the membrane and are also components of the outer layer covering the cyst, where they play a structural role. The synthesis of ARs in A. vinelandii has been shown to occur by the activity of enzymes encoded in the arsABCD operon. The expression of this operon is activated by ArpR, a LysR-type transcriptional regulator whose transcription occurs during encystment and is dependent on the alternative sigma factor RpoS. In this study, we show that the two component response regulator GacA, the small RNA RsmZ1 and the translational repressor protein RsmA, implicated in the control of the synthesis of other cysts components (i.e., alginate and poly-ß-hydroxybutyrate, are also controlling alkylresorcinol synthesis. This control affects the expression of arsABCD and is exerted through the regulation of arpR expression. We show that RsmA negatively regulates arpR expression by binding its mRNA, repressing its translation. GacA in turn, positively regulates arpR expression through the activation of transcription of RsmZ1, that binds RsmA, counteracting its repressor activity. This regulatory cascade is independent of RpoS. We also show evidence suggesting that GacA exerts an additional regulation on arsABCD expression through an ArpR independent route.

  9. Construction safety monitoring based on the project's characteristic with fuzzy logic approach

    Science.gov (United States)

    Winanda, Lila Ayu Ratna; Adi, Trijoko Wahyu; Anwar, Nadjadji; Wahyuni, Febriana Santi

    2017-11-01

    Construction workers accident is the highest number compared with other industries and falls are the main cause of fatal and serious injuries in high rise projects. Generally, construction workers accidents are caused by unsafe act and unsafe condition that can occur separately or together, thus a safety monitoring system based on influencing factors is needed to achieve zero accident in construction industry. The dynamic characteristic in construction causes high mobility for workers while doing the task, so it requires a continuously monitoring system to detect unsafe condition and to protect workers from potential hazards. In accordance with the unique nature of project, fuzzy logic approach is one of the appropriate methods for workers safety monitoring on site. In this study, the focus of discussion is based on the characteristic of construction projects in analyzing "potential hazard" and the "protection planning" to be used in accident prevention. The data have been collected from literature review, expert opinion and institution of safety and health. This data used to determine hazard identification. Then, an application model is created using Delphi programming. The process in fuzzy is divided into fuzzification, inference and defuzzification, according to the data collection. Then, the input and final output data are given back to the expert for assessment as a validation of application model. The result of the study showed that the potential hazard of construction workers accident could be analysed based on characteristic of project and protection system on site and fuzzy logic approach can be used for construction workers accident analysis. Based on case study and the feedback assessment from expert, it showed that the application model can be used as one of the safety monitoring tools.

  10. Radiation safety assessment and development of environmental radiation monitoring technology

    CERN Document Server

    Choi, B H; Kim, S G

    2002-01-01

    The Periodic Safety Review(PSR) of the existing nuclear power plants is required every ten years according to the recently revised atomic energy acts. The PSR of Kori unit 1 and Wolsong unit 1 that have been operating more than ten years is ongoing to comply the regulations. This research project started to develop the techniques necessary for the PSR. The project developed the following four techniques at the first stage for the environmental assessment of the existing plants. 1) Establishment of the assessment technology for contamination and accumulation trends of radionuclides, 2) alarm point setting of environmental radiation monitoring system, 3) Development of Radiation Safety Evaluation Factor for Korean NPP, and 4) the evaluation of radiation monitoring system performance and set-up of alarm/warn set point. A dynamic compartment model to derive a relationship between the release rates of gas phase radionuclides and the concentrations in the environmental samples. The model was validated by comparing ...

  11. Study on Semi-Parametric Statistical Model of Safety Monitoring of Cracks in Concrete Dams

    Directory of Open Access Journals (Sweden)

    Chongshi Gu

    2013-01-01

    Full Text Available Cracks are one of the hidden dangers in concrete dams. The study on safety monitoring models of concrete dam cracks has always been difficult. Using the parametric statistical model of safety monitoring of cracks in concrete dams, with the help of the semi-parametric statistical theory, and considering the abnormal behaviors of these cracks, the semi-parametric statistical model of safety monitoring of concrete dam cracks is established to overcome the limitation of the parametric model in expressing the objective model. Previous projects show that the semi-parametric statistical model has a stronger fitting effect and has a better explanation for cracks in concrete dams than the parametric statistical model. However, when used for forecast, the forecast capability of the semi-parametric statistical model is equivalent to that of the parametric statistical model. The modeling of the semi-parametric statistical model is simple, has a reasonable principle, and has a strong practicality, with a good application prospect in the actual project.

  12. From extended integrity monitoring to the safety evaluation of satellite-based localisation system

    International Nuclear Information System (INIS)

    Legrand, Cyril; Beugin, Julie; Marais, Juliette; Conrard, Blaise; El-Koursi, El-Miloudi; Berbineau, Marion

    2016-01-01

    Global Navigation Satellite Systems (GNSS) such as GPS, already used in aeronautics for safety-related applications, can play a major role in railway safety by allowing a train to locate itself safely. However, in order to implement this positioning solution in any embedded system, its performances must be evaluated according to railway standards. The evaluation of GNSS performances is not based on the same attributes class than RAMS evaluation. Face to these diffculties, we propose to express the integrity attribute, performance of satellite-based localisation. This attribute comes from aeronautical standards and for a hybridised GNSS with inertial system. To achieve this objective, the integrity attribute must be extended to this kind of system and algorithms initially devoted to GNSS integrity monitoring only must be adapted. Thereafter, the formalisation of this integrity attribute permits us to analyse the safety quantitatively through the probabilities of integrity risk and wrong-side failure. In this paper, after an introductory discussion about the use of localisation systems in railway safety context together with integrity issues, a particular integrity monitoring is proposed and described. The detection events of this algorithm permit us to conclude about safety level of satellite-based localisation system.

  13. The micro-processor controlled process radiation monitoring system for reactor safety systems

    International Nuclear Information System (INIS)

    Mizuno, K.; Noguchi, A.; Kumagami, S.; Gotoh, Y.; Kumahara, T.; Arita, S.

    1986-01-01

    Digital computers are soon expected to be applied to various real-time safety and safety-related systems in nuclear power plants. Hitachi is now engaged in the development of a micro-processor controlled process radiation monitoring system, which operates on digital processing methods employed with a log ratemeter. A newly defined methodology of design and test procedures is being applied as a means of software program verification for these safety systems. Recently implemented micro-processor technology will help to achieve an advanced man-machine interface and highly reliable performance. (author)

  14. Modeling the effects of ultrasound power and reactor dimension on the biodiesel production yield: Comparison of prediction abilities between response surface methodology (RSM) and adaptive neuro-fuzzy inference system (ANFIS)

    International Nuclear Information System (INIS)

    Mostafaei, Mostafa; Javadikia, Hossein; Naderloo, Leila

    2016-01-01

    Biodiesel is as an alternative petro-diesel fuel produced from the renewable resources. The use of novel technologies such as ultrasound technology for biodiesel production intensifies the reaction and reduces the process cost. The present study is aimed to evaluate and compare the prediction and simulating efficiency of the response surface methodology (RSM) and adaptive Neuro-fuzzy inference system (ANFIS) approaches for modeling the transesterification yield achieved in ultrasonic reactor. The influence of independent variables (reactor diameter, liquid height and ultrasound intensity) on the conversion of fatty acid methyl esters (FAME) was investigated by Box-Behnken design of RSM and two ANFIS approaches (hybrid and back-propagation optimization methods). All models were compared statistically based on the training and validation data set by the coefficient of determination (R2), root mean squares error (RMSE), mean absolute percentage error (MAPE), mean absolute error (MAE) and mean relative percent deviation (MRPD). The calculated R2 for RSM and two ANFIS models were 0.9669, 0.9812 and 0.9808, respectively. All models indicated good predictions, however, the ANFIS models were more precise compared to the RSM model, which proves that the ANFIS is a powerful tool for modeling and optimizing FAME production in ultrasound reactor. - Highlights: • The ultrasound assisted FAME conversion was modelled using RSM and ANFIS approaches. • The scatter diagrams indicate the models accurately predicted the reaction yield. • The ANFIS model (hybrid) has higher R"2 (0.9812) compared to the RSM model. • The predicted deviations and residual values are relatively small for ANFIS model. • ANFIS model was more accurate for predicting ultrasound assisted FAME conversion.

  15. Flammable gas tank safety program: Technical basis for gas analysis and monitoring

    International Nuclear Information System (INIS)

    Estey, S.D.

    1998-01-01

    Several Hanford waste tanks have been observed to exhibit periodic releases of significant quantities of flammable gases. Because potential safety issues have been identified with this type of waste behavior, applicable tanks were equipped with instrumentation offering the capability to continuously monitor gases released from them. This document was written to cover three primary areas: (1) describe the current technical basis for requiring flammable gas monitoring, (2) update the technical basis to include knowledge gained from monitoring the tanks over the last three years, (3) provide the criteria for removal of Standard Hydrogen Monitoring System(s) (SHMS) from a waste tank or termination of other flammable gas monitoring activities in the Hanford Tank farms

  16. Optimal factor evaluation for the dissolution of alumina from Azaraegbelu clay in acid solution using RSM and ANN comparative analysis

    Directory of Open Access Journals (Sweden)

    P.E. Ohale

    2017-12-01

    Full Text Available Artificial neural network (ANN and Response Surface Methodology based on a 25−1 fractional factorial design were used as tools for simulation and optimisation of the dissolution process for Azaraegbelu clay. A feedforward neural network model with Levenberg–Marquard back propagating training algorithm was adapted to predict the response (alumina yield. The studied input variables were temperature, stirring speed, clay to acid dosage, leaching time and leachant concentration. The raw clay was characterized for structure elucidation via FTIR, SEM and X-ray diffraction spectroscopic techniques and the result indicates that the clay is predominantly kaolinite. Leachant concentration and dosage ratio were found to be the most significant process parameter with p-value of 0.0001. The performance of the ANN and RSM model showed adequate prediction of the response, with AAD of 11.6% and 3.6%, and R2 of 0.9733 and 0.9568, respectively. A non-dominated optimal response of 81.45% yield of alumina at 4.6 M sulphuric acid concentration, 214 min leaching time, 0.085 g/ml dosage and 214 rpm stirring speed was established as a viable route for reduced material and operating cost via RSM. Keywords: Alumina dissolution, ANN modelling, Azaraegbelu, Clay, RSM

  17. Numerical Optimization of Impeller for Backward-Curved Centrifugal Fan by Response Surface Methodology (RSM)

    OpenAIRE

    Fannian Meng; Quanlin Dong; Yan Wang; Pengfei Wang; Chunxi Zhang

    2013-01-01

    A numerical optimum study on three-dimensional unsteady viscous flow in a centrifugal fan with backward-curved blades was performed. The influence of the inlet angle, the outlet blade angle and blade number on aerodynamic performance of the centrifugal fan was analyzed concerning the whole impeller-volute configuration. Response Surface Methodology (RSM) based on a three-level, three -variable Box-Behnken Design (BBD) was used to evaluate the interactive effects of factors such as inlet blade...

  18. The new Basic Safety Standards Directive and its implications for environmental monitoring

    International Nuclear Information System (INIS)

    Janssens, Augustin; Necheva, Christina; Tanner, Vesa; Turai, István

    2013-01-01

    Monitoring of levels of radioactivity in the environment is enshrined in Chapter 3 of the Euratom Treaty, in particular its Articles 35 and 36. These requirements in primary law have had an important impact on the importance of monitoring in Europe but have not been worked out in much detail in secondary legislation. The consolidation and revision of the Basic Safety Standards Directive was an opportunity for doing so. The requirements in Directive 96/29/Euratom had remained rather general. Now, more specific text is introduced on the establishment of discharge authorisations for radioactive effluents, and on monitoring these discharges. Requirements on estimation of public exposures and on environmental monitoring programmes have largely been copied from the old basic safety standards (BSS), however. The main novelty of the new BSS is the introduction of exposure situations, as defined by the ICRP in Publication 103 (2007). Environmental monitoring as part of the management of an emergency exposure situation is now addressed more clearly. As for existing exposure situations, indoor exposure to radon requires extensive surveys of indoor air or soil concentrations, and precise requirements are made on the management of residues from industries processing naturally occurring radioactive materials (NORM) as well as on the monitoring of building materials. Although the BSS do not address specific monitoring issues, studies have been undertaken on effluents from hospitals and on long-term management of uranium mining areas. The proposal for the new Basic Safety Standards Directive is examined in the light of experience of the accident at Fukushima Dai-ichi Nuclear Power Plant disabled by the terrible tsunami on 11 March 2011. The arrangements for information exchange in a normal situation and in an emergency exposure situation need to be looked at from this perspective as well as from the perspective of smaller incidents such as the release of 131 I in Hungary in autumn

  19. A Fiber Bragg Grating-Based Monitoring System for Roof Safety Control in Underground Coal Mining

    Directory of Open Access Journals (Sweden)

    Yiming Zhao

    2016-10-01

    Full Text Available Monitoring of roof activity is a primary measure adopted in the prevention of roof collapse accidents and functions to optimize and support the design of roadways in underground coalmines. However, traditional monitoring measures, such as using mechanical extensometers or electronic gauges, either require arduous underground labor or cannot function properly in the harsh underground environment. Therefore, in this paper, in order to break through this technological barrier, a novel monitoring system for roof safety control in underground coal mining, using fiber Bragg grating (FBG material as a perceived element and transmission medium, has been developed. Compared with traditional monitoring equipment, the developed, novel monitoring system has the advantages of providing accurate, reliable, and continuous online monitoring of roof activities in underground coal mining. This is expected to further enable the prevention of catastrophic roof collapse accidents. The system has been successfully implemented at a deep hazardous roadway in Zhuji Coal Mine, China. Monitoring results from the study site have demonstrated the advantages of FBG-based sensors over traditional monitoring approaches. The dynamic impacts of progressive face advance on roof displacement and stress have been accurately captured by the novel roadway roof activity and safety monitoring system, which provided essential references for roadway support and design of the mine.

  20. Plasma, a plant safety monitoring and assessment system for VVER-440 reactors

    Energy Technology Data Exchange (ETDEWEB)

    Hornaes, A.; Hulsund, J. E. [Institutt for energiteknikk (IFE), OECD Halden Reactor Project, Halden (Norway); Lipcsei, S.; Major, Cs.; Racz, A.; Vegh, J. [KFKI, Atomic Energy Research Institute, Budapest (Hungary); Eiler, J. [Paks, Nuclear Power Plant Ltd, Paks (Hungary)

    1999-05-15

    The objective with the Plant Safety Monitoring and Assessment System (PLASMA) is to develop an operator support system to support the execution of new symptom-based Emergency Operating Procedures for application in VVER reactors, with the Paks NPP in Hungary as the target plant. Many of the VVER reactors are rewriting their EOPs to comply more with Western standards of symptom-based EOPs. In this connection it is desirable to improve the data validation, information integration and presentation for operators when executing the EOPs. The entry-point to a symptom-oriented procedure is defined by the occurrence of a well-defined reactor operation status, with all its symptoms. However, the application of the EOF benefits from an operator support system, which performs plant status and symptom identification reliably and accurately. The development of the PLASMA system is a joint venture between Institutt for energiteknikk (IFE) and KFKI with the NPP Paks as the target plant. The project has been initiated and partly funded by the Science and Technology Agency (STA), Japan through the OECD NEA assistance program. In Hungary, considerable effort has concentrated on the safety reassessment of the Paks NPP and new EOPs are being written, but no comprehensive Operator Support System (OSS) for plant safety assessment is installed. Some safety parameter display functions are incorporated into diverse operator support systems, but an online 'plant safety monitoring and assessment system' is still missing. The present project comprises designing, constructing, testing and installing such an OSS, which to a great extent could support plant operators in their safety assessment work (author) (ml)

  1. A Study on Drug Safety Monitoring Program in India

    Science.gov (United States)

    Ahmad, A.; Patel, Isha; Sanyal, Sudeepa; Balkrishnan, R.; Mohanta, G. P.

    2014-01-01

    Pharmacovigilance is useful in assuring the safety of medicines and protecting the consumers from their harmful effects. A number of single drugs as well as fixed dose combinations have been banned from manufacturing, marketing and distribution in India. An important issue about the availability of banned drugs over the counter in India is that sufficient adverse drug reactions data about these drugs have not been reported. The most common categories of drugs withdrawn in the last decade were nonsteroidal antiinflammatory drugs (28%), antidiabetics (14.28%), antiobesity (14.28%), antihistamines (14.28%), gastroprokinetic drugs (7.14%), breast cancer and infertility drugs (7.14%), irritable bowel syndrome and constipation drugs (7.14%) and antibiotics (7.14%). Drug withdrawals from market were made mainly due to safety issues involving cardiovascular events (57.14%) and liver damage (14.28%). Majority of drugs have been banned since 3-5 years in other countries but are still available for sale in India. The present study compares the drug safety monitoring systems in the developed countries such as the USA and UK and provides implications for developing a system that can ensure the safety and efficacy of drugs in India. Absence of a gold standard for a drug safety surveillance system, variations in culture and clinical practice across countries makes it difficult for India to completely adopt another country's practices. There should be a multidisciplinary approach towards drug safety that should be implemented throughout the entire duration spanning from drug discovery to usage by consumers. PMID:25425751

  2. Optimizing culture conditions for production of intra and extracellular inulinase and invertase from Aspergillus niger ATCC 20611 by response surface methodology (RSM).

    Science.gov (United States)

    Dinarvand, Mojdeh; Rezaee, Malahat; Foroughi, Majid

    The aim of this study was obtain a model that maximizes growth and production of inulinase and invertase by Aspergillus niger ATCC 20611, employing response surface methodology (RSM). The RSM with a five-variable and three-level central composite design (CCD) was employed to optimize the medium composition. Results showed that the experimental data could be appropriately fitted into a second-order polynomial model with a coefficient of determination (R 2 ) more than 0.90 for all responses. This model adequately explained the data variation and represented the actual relationships between the parameters and responses. The pH and temperature value of the cultivation medium were the most significant variables and the effects of inoculum size and agitation speed were slightly lower. The intra-extracellular inulinase, invertase production and biomass content increased 10-32 fold in the optimized medium condition (pH 6.5, temperature 30°C, 6% (v/v), inoculum size and 150rpm agitation speed) by RSM compared with medium optimized through the one-factor-at-a-time method. The process development and intensification for simultaneous production of intra-extracellular inulinase (exo and endo inulinase) and invertase from A. niger could be used for industrial applications. Copyright © 2017 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. All rights reserved.

  3. Monitoring system of arch bridge for safety network management

    Science.gov (United States)

    Joo, Bong Chul; Yoo, Young Jun; Lee, Chin Hyung; Park, Ki Tae; Hwang, Yoon Koog

    2010-03-01

    Korea has constructed the safety management network monitoring test systems for the civil infrastructure since 2006 which includes airport structure, irrigation structure, railroad structure, road structure, and underground structure. Bridges among the road structure include the various superstructure types which are Steel box girder bridge, suspension bridge, PSC-box-girder bridge, and arch bridge. This paper shows the process of constructing the real-time monitoring system for the arch bridge and the measured result by the system. The arch type among various superstructure types has not only the structural efficiency but the visual beauty, because the arch type superstructure makes full use of the feature of curve. The main measuring points of arch bridges composited by curved members make a difference to compare with the system of girder bridges composited by straight members. This paper also shows the method to construct the monitoring system that considers the characteristic of the arch bridge. The system now includes strain gauges and thermometers, and it will include various sensor types such as CCTV, accelerometers and so on additionally. For the long term and accuracy monitoring, the latest optical sensors and equipments are applied to the system.

  4. Crystal Structure of the Thermus thermophilus 16 S rRNA Methyltransferase RsmC in Complex with Cofactor and Substrate Guanosine

    Energy Technology Data Exchange (ETDEWEB)

    Demirci, H.; Gregory, S; Dahlberg, A; Jogl, G

    2008-01-01

    Post-transcriptional modification is a ubiquitous feature of ribosomal RNA in all kingdoms of life. Modified nucleotides are generally clustered in functionally important regions of the ribosome, but the functional contribution to protein synthesis is not well understood. Here we describe high resolution crystal structures for the N{sup 2}-guanine methyltransferase RsmC that modifies residue G1207 in 16 S rRNA near the decoding site of the 30 S ribosomal subunit. RsmC is a class I S-adenosyl-l-methionine-dependent methyltransferase composed of two methyltransferase domains. However, only one S-adenosyl-l-methionine molecule and one substrate molecule, guanosine, bind in the ternary complex. The N-terminal domain does not bind any cofactor. Two structures with bound S-adenosyl-l-methionine and S-adenosyl-l-homocysteine confirm that the cofactor binding mode is highly similar to other class I methyltransferases. Secondary structure elements of the N-terminal domain contribute to cofactor-binding interactions and restrict access to the cofactor-binding site. The orientation of guanosine in the active site reveals that G1207 has to disengage from its Watson-Crick base pairing interaction with C1051 in the 16 S rRNA and flip out into the active site prior to its modification. Inspection of the 30 S crystal structure indicates that access to G1207 by RsmC is incompatible with the native subunit structure, consistent with previous suggestions that this enzyme recognizes a subunit assembly intermediate.

  5. Considerations on monitoring needs of advanced, passive safety light water reactors for severe accident management

    International Nuclear Information System (INIS)

    Bava, G.; Zambardi, F.

    1992-01-01

    This paper deals with problems concerning information and related instrumentation needs for Accident Management (AM), with special emphasis on Severe Accidents (SA) in the new advanced, passive safety Light Water Reactors (PLWR), presently in a development stage. The passive safety conception adopted in the plants concerned goes parallel with a deeper consideration of SA, that reflects the need of increasing the plant resistance against conditions going beyond traditional ''design basis accidents''. Further, the role of Accident Management (AM) is still emphasized as last step of the defence in depth concept, in spite of the design efforts aimed to reduce human factor importance; as a consequence, the availability of pertinent information on actual plant conditions remains a necessary premise for performing preplanned actions. This information is essential to assess the evolution of the accident scenarios, to monitor the performances of the safety systems, to evaluate the ultimate challenge to the plant safety, and to implement the emergency operating procedures and the emergency plans. Based on these general purposes, the impact of the new conception on the monitoring structure is discussed, furthermore reference is made to the accident monitoring criteria applied in current plants to evaluate the requirements for possible solutions. (orig.)

  6. Shrinkage Analysis on Thick Plate Part using Response Surface Methodology (RSM

    Directory of Open Access Journals (Sweden)

    Isafiq M.

    2016-01-01

    Full Text Available The work reported herein is about an analysis on the quality (shrinkage on a thick plate part using Response Surface Methodology (RSM. Previous researches showed that the most influential factor affecting the shrinkage on moulded parts are mould and melt temperature. Autodesk Moldflow Insight software was used for the analysis, while specifications of Nessei NEX 1000 injection moulding machine and P20 mould material were incorporated in this study on top of Acrylonitrile Butadiene Styrene (ABS as a moulded thermoplastic material. Mould temperature, melt temperature, packing pressure and packing time were selected as variable parameters. The results show that the shrinkage have improved 42.48% and 14.41% in parallel and normal directions respectively after the optimisation process.

  7. The roles of the seismic safety and monitoring systems in the PEC fast reactor

    International Nuclear Information System (INIS)

    Masoni, P.; Di Tullio, E.M.; Massa, B.; Martelli, A.; Sano, T.

    1988-01-01

    Two different seismic systems are foreseen in the case of PEC: the seismic safety system, that provides the automatic scram, and the seismic monitoring system. During earthquake, three triaxial seismic switches are triggered if a threshold value of the ground acceleration is exceeded. In this case, the signals from the seismic switches are processed by the safety system (with a 2/3 logic) and the shutdown system is triggered. Peak acceleration is the parameter used by the safety system to quantify the seismic event. This way, however, no information is obtained with regard to earthquake frequency content. Thus, reactor safety is guaranteed by adopting a threshold considerably lower than the Z.P.A. of the Design Basis Earthquake. Furthermore, in the case of significant earthquakes, the seismic motion is measured by about 20 triaxial accelerometers, located both in the free field and on the plant's structures. Data are digitazed and recordered by the seismic monitoring system. This system also elaborates the recordered time-histories providing floor response spectra and compares such spectra to the design values. The above-mentioned elaborations and comparisons are performed in short time for two triaxial measuring positions, thus allowing the Operator to immediately get a more complete information on the seismic event. The complete set of data recorded by the seismic monitoring system also allows the actual dynamic response of the plant to be determined and compared to the design values. On the basis of this comparison the necessary safety analysis can be carried out to verify whether the design limits of the plant were respected: in the positive case the reactor can be restarted. (author)

  8. [Enlightenment of adverse reaction monitoring on safety evaluation of traditional Chinese medicines].

    Science.gov (United States)

    Song, Hai-bo; Du, Xiao-xi; Ren, Jing-tian; Yang, Le; Guo, Xiao-xin; Pang, Yu

    2015-04-01

    The adverse reaction monitoring is important in warning the risks of traditional Chinese medicines at an early stage, finding potential quality problems and ensuring the safe clinical medication. In the study, efforts were made to investigate the risk signal mining techniques in line with the characteristics of traditional Chinese medicines, particularly the complexity in component, processing, compatibility, preparation and clinical medication, find early risk signals of traditional Chinese medicines and establish a traditional Chinese medicine safety evaluation system based on adverse reaction risk signals, in order to improve the target studies on traditional Chinese medicine safety, effective and timely control risks and solve the existing frequent safety issue in traditional Chinese medicines.

  9. Statistical Optimization of Conditions for Decolorization of Synthetic Dyes by Cordyceps militaris MTCC 3936 Using RSM

    Directory of Open Access Journals (Sweden)

    Baljinder Kaur

    2015-01-01

    Full Text Available In the present study, the biobleaching potential of white rot fungus Cordyceps militaris MTCC3936 was investigated. For preliminary screening, decolorization properties of C. militaris were comparatively studied using whole cells in agar-based and liquid culture systems. Preliminary investigation in liquid culture systems revealed 100% decolorization achieved within 3 days of incubation for reactive yellow 18, 6 days for reactive red 31, 7 days for reactive black 8, and 11 days for reactive green 19 and reactive red 74. RSM was further used to study the effect of three independent variables such as pH, incubation time, and concentration of dye on decolorization properties of cell free supernatant of C. militaris. RSM based statistical analysis revealed that dye decolorization by cell free supernatants of C. militaris is more efficient than whole cell based system. The optimized conditions for decolorization of synthetic dyes were identified as dye concentration of 300 ppm, incubation time of 48 h, and optimal pH value as 5.5, except for reactive red 31 (for which the model was nonsignificant. The maximum dye decolorizations achieved under optimized conditions for reactive yellow 18, reactive green 19, reactive red 74, and reactive black 8 were 73.07, 65.36, 55.37, and 68.59%, respectively.

  10. Condition Monitoring and Fault Diagnosis for an Antifalling Safety Device

    Directory of Open Access Journals (Sweden)

    Guangxiang Yang

    2015-01-01

    Full Text Available There is a constant need for the safe operation and reliability of antifalling safety device (AFSD of an elevator. This paper reports an experimental study on rotation speed and catching torque monitoring and fault diagnosis of an antifalling safety device in a construction elevator. Denoising the signal using wavelet transform is presented in this paper. Based on the denoising effects for several types of wavelets, the sym8 wavelet basis, which introduces the high order approximation and an adaptive threshold, is employed for denoising the signal. The experimental result shows a maximum data error reduction of 7.5% is obtained and SNRs (signal-to-noise ratio of rotation speed and catching torque are improved for 3.9% and 6.4%, respectively.

  11. Alizarin Complexone Functionalized Mesoporous Silica Nanoparticles: A Smart System Integrating Glucose-Responsive Double-Drugs Release and Real-Time Monitoring Capabilities.

    Science.gov (United States)

    Zou, Zhen; He, Dinggeng; Cai, Linli; He, Xiaoxiao; Wang, Kemin; Yang, Xue; Li, Liling; Li, Siqi; Su, Xiaoya

    2016-04-06

    The outstanding progress of nanoparticles-based delivery systems capable of releasing hypoglycemic drugs in response to glucose has dramatically changed the outlook of diabetes management. However, the developed glucose-responsive systems have not offered real-time monitoring capabilities for accurate quantifying hypoglycemic drugs released. In this study, we present a multifunctional delivery system that integrates both delivery and monitoring issues using glucose-triggered competitive binding scheme on alizarin complexone (ALC) functionalized mesoporous silica nanoparticles (MSN). In this system, ALC is modified on the surface of MSN as the signal reporter. Gluconated insulin (G-Ins) is then introduced onto MSN-ALC via benzene-1,4-diboronic acid (BA) mediated esterification reaction, where G-Ins not only blocks drugs inside the mesopores but also works as a hypoglycemic drug. In the absence of glucose, the sandwich-type boronate ester structure formed by BA binding to the diols of ALC and G-Ins remains intact, resulting in an fluorescence emission peak at 570 nm and blockage of pores. Following a competitive binding, the presence of glucose cause the dissociation of boronate ester between ALC and BA, which lead to the pores opening and disappearance of fluorescence. As proof of concept, rosiglitazone maleate (RSM), an insulin-sensitizing agent, was doped into the MSN to form a multifunctional MSN (RSM@MSN-ALC-BA-Ins), integrating with double-drugs loading, glucose-responsive performance, and real-time monitoring capability. It has been demonstrated that the glucose-responsive release behaviors of insulin and RSM in buffer or in human serum can be quantified in real-time through evaluating the changes of fluorescence signal. We believe that this developed multifunctional system can shed light on the invention of a new generation of smart nanoformulations for optical diagnosis, individualized treatment, and noninvasive monitoring of diabetes management.

  12. Geoelectrical Methods and Monitoring for Dam Safety Assessment, Republic of Korea

    Science.gov (United States)

    Lim, S. K.; Oldenburg, D.; Kang, S.; Song, S. H.

    2016-12-01

    Geoelectrical methods and monitoring to detect the seepage and internal erosion are essential for the safety assessment of earth dams. This work aims to develop improved methodologies to analyze the observed data and to monitor changes in seepage flow using direct current (DC) and self-potential (SP) methods. The seasonal variation of water level at dams causes a change in seepage and water saturation and hence alters the resistivity of the dam material. DC data are sensitive to water saturation and hence changes in saturation can be obtained by repeatedly measuring DC data. However, a more diagnostic parameter for safety assessment is fluid flow, and resistivity is only weakly coupled to that. Fortunately SP signals are directly related to fluid flow, and thus an SP survey has the potential to characterize fluid flow through the earth matrix. In Korea, the safety assessment of earth fill dams has been dealt by Korea Rural Community Corporation (KRC). Most of the dams are relatively old ( >50 years), hence assessing deterioration and corresponding seepage of those dams are crucial. In order to evaluate the engineering geological properties of the soil at earth dams in Korea, two boreholes in each dam were drilled to a bedrock depth that exceeds the height of the dam. A large set of field tests, including standard penetration tests (SPT) and in-situ permeability tests, were carried out along the boreholes. However, seepage paths in the dam is complex hence those limited measurements at a few points is not sufficient to delineate the zone of preferential seepage flow. For this, KRC developed permanent DC monitoring systems at a number of agricultural dams in Korea. The data were automatically collected every 6 hours. During the monitoring, the measurements of the water level at two boreholes were gathered at the same time. In this presentation we select an agricultural dam and delineate an anomalous leakage zone by inverting and interpreting time-lapse DC resistivity

  13. Real-Time Safety Monitoring and Prediction for the National Airspace System

    Science.gov (United States)

    Roychoudhury, Indranil

    2016-01-01

    As new operational paradigms and additional aircraft are being introduced into the National Airspace System (NAS), maintaining safety in such a rapidly growing environment becomes more challenging. It is therefore desirable to have both an overview of the current safety of the airspace at different levels of granularity, as well an understanding of how the state of the safety will evolve into the future given the anticipated flight plans, weather forecasts, predicted health of assets in the airspace, and so on. To this end, we have developed a Real-Time Safety Monitoring (RTSM) that first, estimates the state of the NAS using the dynamic models. Then, given the state estimate and a probability distribution of future inputs to the NAS, the framework predicts the evolution of the NAS, i.e., the future state, and analyzes these future states to predict the occurrence of unsafe events. The entire probability distribution of airspace safety metrics is computed, not just point estimates, without significant assumptions regarding the distribution type and or parameters. We demonstrate our overall approach by predicting the occurrence of some unsafe events and show how these predictions evolve in time as flight operations progress.

  14. Enabling social listening for cardiac safety monitoring: Proceedings from a drug information association-cardiac safety research consortium cosponsored think tank.

    Science.gov (United States)

    Seifert, Harry A; Malik, Raleigh E; Bhattacharya, Mondira; Campbell, Kevin R; Okun, Sally; Pierce, Carrie; Terkowitz, Jeffrey; Turner, J Rick; Krucoff, Mitchell W; Powell, Gregory E

    2017-12-01

    This white paper provides a summary of the presentations and discussions from a think tank on "Enabling Social Listening for Cardiac Safety Monitoring" trials that was cosponsored by the Drug Information Association and the Cardiac Safety Research Consortium, and held at the White Oak headquarters of the US Food and Drug Administration on June 3, 2016. The meeting's goals were to explore current methods of collecting and evaluating social listening data and to consider their applicability to cardiac safety surveillance. Social listening is defined as the act of monitoring public postings on the Internet. It has several theoretical advantages for drug and device safety. First, these include the ability to detect adverse events that are "missed" by traditional sources and the ability to detect adverse events sooner than would be allowed by traditional sources, both by affording near-real-time access to data from culturally and geographically diverse sources. Social listening can also potentially introduce a novel patient voice into the conversation about drug safety, which could uniquely augment understanding of real-world medication use obtained from more traditional methodologies. Finally, it can allow for access to information about drug misuse and diversion. To date, the latter 2 of these have been realized. Although regulators from the Food and Drug Administration and the United Kingdom's Medicines and Healthcare Products Regulatory Agency participated in the think tank along with representatives from industry, academia, and patient groups, this article should not be construed to constitute regulatory guidance. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. HSI for monitoring the critical safety functions status tree of a NPP

    International Nuclear Information System (INIS)

    Oliveira, Mauro Vitor de; Almeida, Jose Carlos Soares de; Augusto, Silas Cordeiro; Jaime, Guilherme Dutra Gonzaga

    2013-01-01

    Critical safety function (CSF) is the most significant design concept for prioritize operator actions based on the potential threat to the three barriers (fuel cladding, primary coolant system boundary, and containment) and allows the operator to respond to these threats prior to event diagnosis. CSF has a hierarchical information structure that organizes the system variables affecting the plant safety in terms of goal-means relations. It is important that the operator should be aware of various success paths associated with each CSF in order to respond to unanticipated system failures quickly. When an emergency occurs in NPPs, the operator should monitor CSFs periodically and identify possible success paths as necessary, and try to stabilize or safely shut down the plant using emergency operating procedure (EOP) that includes steps to check the CSFs. This implies that safety function status check may become a cognitively burdensome task that needs to be supported by proper information display. The advanced human-system interface (HSI) in nuclear power plants provides an information environment that supports the operators' burdensome cognitive tasks. This paper describes a CSFs interface design for supporting the operator's tasks to monitor and identify the associated success path for Westinghouse 3-loops NPP. (author)

  16. Criticality safety considerations. Integral Monitored Retrievable Storage (MRS) Facility

    International Nuclear Information System (INIS)

    1986-09-01

    This report summarizes the criticality analysis performed to address criticality safety concerns and to support facility design during the conceptual design phase of the Monitored Retrievable Storage (MRS) Facility. The report addresses the criticality safety concerns, the design features of the facility relative to criticality, and the results of the analysis of both normal operating and hypothetical off-normal conditions. Key references are provided (Appendix C) if additional information is desired by the reader. The MRS Facility design was developed and the related analysis was performed in accordance with the MRS Facility Functional Design Criteria and the Basis for Design. The detailed description and calculations are documented in the Integral MRS Facility Conceptual Design Report. In addition to the summary portion of this report, explanatary notes for various terms, calculation methodology, and design parameters are presented in Appendix A. Appendix B provides a brief glossary of technical terms

  17. Introduction of structural health and safety monitoring warning systems for Shenzhen-Hong Kong Western Corridor Shenzhen Bay Bridge

    Science.gov (United States)

    Li, N.; Zhang, X. Y.; Zhou, X. T.; Leng, J.; Liang, Z.; Zheng, C.; Sun, X. F.

    2008-03-01

    Though the brief introduction of the completed structural health and safety monitoring warning systems for Shenzhen-Hongkong western corridor Shenzhen bay highway bridge (SZBHMS), the self-developed system frame, hardware and software scheme of this practical research project are systematically discussed in this paper. The data acquisition and transmission hardware and the basic software based on the NI (National Instruments) Company virtual instruments technology were selected in this system, which adopted GPS time service receiver technology and so on. The objectives are to establish the structural safety monitoring and status evaluation system to monitor the structural responses and working conditions in real time and to analyze the structural working statue using information obtained from the measured data. It will be also provided the scientific decision-making bases for the bridge management and maintenance. Potential technical approaches to the structural safety warning systems, status identification and evaluation method are presented. The result indicated that the performance of the system has achieved the desired objectives, ensure the longterm high reliability, real time concurrence and advanced technology of SZBHMS. The innovate achievement which is the first time to implement in domestic, provide the reference for long-span bridge structural health and safety monitoring warning systems design.

  18. Optimization on cooperative feed strategy for radial–axial ring rolling process of Inco718 alloy by RSM and FEM

    Directory of Open Access Journals (Sweden)

    Zhu Xinglin

    2016-06-01

    Full Text Available During radial–axial ring rolling process, cooperative strategy of the radial–axial feed is critical for dimensional accuracy and thermo mechanical parameters distribution of the formed ring. In order to improve the comprehensive quality of the ring parts, response surface method (RSM is employed for the first time to optimize the cooperative feed strategy for radial–axial ring rolling process by combining it with an improved and verified 3D coupled thermo-mechanical finite element model. The feed trajectory is put forward to describe cooperative relationship of the radial–axial feed and three variables are designed based on the feed trajectory. In order to achieve multi-objective optimization, four responses including thermo mechanical parameters distribution and rolling force are proposed. Based on the FEM results, RSM is used to establish a response model to depict the function relationship between the objective response and design variables. Through this approximate model, effects of different variables on ring rolling process are analyzed connectedly and optimal feed strategy is obtained by resorting to the optimal chart specific to a constraint condition.

  19. Intelligent Packaging Systems: Sensors and Nanosensors to Monitor Food Quality and Safety

    Directory of Open Access Journals (Sweden)

    Guillermo Fuertes

    2016-01-01

    Full Text Available The application of nanotechnology in different areas of food packaging is an emerging field that will grow rapidly in the coming years. Advances in food safety have yielded promising results leading to the development of intelligent packaging (IP. By these containers, it is possible to monitor and provide information of the condition of food, packaging, or the environment. This article describes the role of the different concepts of intelligent packaging. It is possible that this new technology could reach enhancing food safety, improving pathogen detection time, and controlling the quality of food and packaging throughout the supply chain.

  20. Assessment of pharmacovigilance approaches for monitoring the safety of antimalarial drugs in pregnancy

    NARCIS (Netherlands)

    Dellicour, S.O.M.C.

    2014-01-01

    Post-marketing surveillance of drugs used in pregnancy is challenging, especially in developing countries where resources for pharmacovigilance are rare. There is a need to establish simple but effective systems to monitor safety of drugs given during pregnancy in resource constrained countries.

  1. Research on Safety Monitoring System of Tailings Dam Based on Internet of Things

    Science.gov (United States)

    Wang, Ligang; Yang, Xiaocong; He, Manchao

    2018-03-01

    The paper designed and implemented the safety monitoring system of tailings dam based on Internet of things, completed the hardware and software design of sensor nodes, routing nodes and coordinator node by using ZigBee wireless sensor chip CC2630 and 3G/4G data transmission module, developed the software platform integrated with geographic information system. The paper achieved real-time monitoring and data collection of tailings dam dam deformation, seepage line, water level and rainfall for all-weather, the stability of tailings dam based on the Internet of things monitoring is analyzed, and realized intelligent and scientific management of tailings dam under the guidance of the remote expert system.

  2. Technical diagnostics - equipment monitoring for increasing safety and availability of nuclear power plants

    International Nuclear Information System (INIS)

    Sturm, A.; Foerster, R.

    1977-01-01

    Utilization of technical diagnostics in equipment monitoring of nuclear power plants for ensuring nuclear safety, economic availability, and for decision making on necessary maintenance is reviewed. Technical diagnostics is subdivided into inspection and early detection of malfunctions. Moreover, combination of technical diagnostics and equipment monitoring, integration of technical diagnostics into maintenance strategy, and problems of introducing early detection of malfunctions into maintenance management of nuclear power plants are also discussed. In addition, a compilation of measuring techniques used in technical diagnostics has been made. The international state of the art of equipment monitoring in PWR nuclear power plants is illustrated by description of the sound and vibration measuring techniques. (author)

  3. Multi-objective shape optimization of double pipe heat exchanger with inner corrugated tube using RSM method

    International Nuclear Information System (INIS)

    Han, Huai-Zhi; Li, Bing-Xi; Wu, Hao; Shao, Wei

    2015-01-01

    Integrated a fully developing three-dimensional heat transfer and flow model, a multi-objective optimization aims to fulfill the geometric design for double-tube heat exchangers with inner corrugated tube is investigated in this work with RSM. Dimensionless corrugation pitch (p/D), dimensionless corrugation height (H/D), dimensionless corrugation radius (r/D) and Reynolds number (Re) are considered as four design parameters. Considering the process parameters, the characteristic numbers involving heat transfer characteristic, resistance characteristic and overall heat transfer performance calculated by CFD, and are served as objective functions to the RSM (Nu c , f c , Nu c /Nu s , f c /f s and h in this paper). The results of optimal designs are a set of multiple optimum solutions, called 'Pareto optimal solutions'. It reveals the identical tendency of Nu c /Nu s and f c /f s reflecting the conflict between them that means augmenting the heat transfer performance with various design parameters in the optimal situation inevitably sacrificed the increase of flow resistance. According to the Pareto optimal curves, the optimum designing parameters of double pipe heat exchanger with inner corrugated tube under the constrains of Nu c /Nu s ≥1.2 are found to be P/D = 0.82, H/D = 0.22, r/D = 0.23, Re = 26,263, corresponding to the maximum value of η = 1.12. (authors)

  4. Network analytical tool for monitoring global food safety highlights China.

    Directory of Open Access Journals (Sweden)

    Tamás Nepusz

    Full Text Available BACKGROUND: The Beijing Declaration on food safety and security was signed by over fifty countries with the aim of developing comprehensive programs for monitoring food safety and security on behalf of their citizens. Currently, comprehensive systems for food safety and security are absent in many countries, and the systems that are in place have been developed on different principles allowing poor opportunities for integration. METHODOLOGY/PRINCIPAL FINDINGS: We have developed a user-friendly analytical tool based on network approaches for instant customized analysis of food alert patterns in the European dataset from the Rapid Alert System for Food and Feed. Data taken from alert logs between January 2003-August 2008 were processed using network analysis to i capture complexity, ii analyze trends, and iii predict possible effects of interventions by identifying patterns of reporting activities between countries. The detector and transgressor relationships are readily identifiable between countries which are ranked using i Google's PageRank algorithm and ii the HITS algorithm of Kleinberg. The program identifies Iran, China and Turkey as the transgressors with the largest number of alerts. However, when characterized by impact, counting the transgressor index and the number of countries involved, China predominates as a transgressor country. CONCLUSIONS/SIGNIFICANCE: This study reports the first development of a network analysis approach to inform countries on their transgressor and detector profiles as a user-friendly aid for the adoption of the Beijing Declaration. The ability to instantly access the country-specific components of the several thousand annual reports will enable each country to identify the major transgressors and detectors within its trading network. Moreover, the tool can be used to monitor trading countries for improved detector/transgressor ratios.

  5. Optimization of microwave-assisted extraction of total extract, stevioside and rebaudioside-A from Stevia rebaudiana (Bertoni) leaves, using response surface methodology (RSM) and artificial neural network (ANN) modelling.

    Science.gov (United States)

    Ameer, Kashif; Bae, Seong-Woo; Jo, Yunhee; Lee, Hyun-Gyu; Ameer, Asif; Kwon, Joong-Ho

    2017-08-15

    Stevia rebaudiana (Bertoni) consists of stevioside and rebaudioside-A (Reb-A). We compared response surface methodology (RSM) and artificial neural network (ANN) modelling for their estimation and predictive capabilities in building effective models with maximum responses. A 5-level 3-factor central composite design was used to optimize microwave-assisted extraction (MAE) to obtain maximum yield of target responses as a function of extraction time (X 1 : 1-5min), ethanol concentration, (X 2 : 0-100%) and microwave power (X 3 : 40-200W). Maximum values of the three output parameters: 7.67% total extract yield, 19.58mg/g stevioside yield, and 15.3mg/g Reb-A yield, were obtained under optimum extraction conditions of 4min X 1 , 75% X 2 , and 160W X 3 . The ANN model demonstrated higher efficiency than did the RSM model. Hence, RSM can demonstrate interaction effects of inherent MAE parameters on target responses, whereas ANN can reliably model the MAE process with better predictive and estimation capabilities. Copyright © 2017. Published by Elsevier Ltd.

  6. Identification of Challenges and Opportunities for Regional Sediment Management (RSM) and Engineering with Nature (EWN) within Inland USACE Districts

    Science.gov (United States)

    2016-07-01

    HEC numerical modeling and data collection capabilities, and sediment challenges in river and reservoir systems. In addition to the presentations, much...the sediment impact analysis methods (SIAM) in HEC - RAS . In Proceedings, Eighth Joint Federal Interagency Sedimentation Conference. Reno, NV...partnerships, (b) identify both challenges and opportunities in incorporating RSM and EWN into inland river , reservoir, and watershed systems, and (c

  7. Removal of Methyl Red from Aqueous Solution by Adsorption on Treated Banana Pseudo stem Fibers Using Response Surface Method (RSM)

    International Nuclear Information System (INIS)

    Zaida Rahayu Yet; Mohd Zulkhairi Abdul Rahim

    2014-01-01

    The effect of adsorbent dose, pH and contact times on the removal of Methyl Red (MR) from aqueous solution by using agriculture waste (NaOH treated banana pseudo stem fibers) were studied. The influence of these parameters on the removal of Methyl Red was examined by using a response surface method (RSM). The experiment was conducted by combining three parameters: adsorbent dose (500-1500 mg/L), pH (2-8) dan contact time (5-75 minutes ). The Box-Behnken Design (BBD) in Response Surface Methodology (RSM) by Design Expert Version 8.0.4 (Stat Ease, USA) was used for designing the experiments. Results showed that the optimum conditions for removal of Methyl Red from an aqueous solution (100 mg/L) were as follows: adsorbent dose (1417.70 mg/L), pH (2.08) and contact time (42.94 minutes) with the value of a coefficient of determination, R2 is 98.98 %. Meanwhile, the second-order polynomial equation indicates that pH and contact times mostly affect the removal of Methyl Red. (author)

  8. Analyzing parameters optimisation in minimising warpage on side arm using response surface methodology (RSM)

    Science.gov (United States)

    Rayhana, N.; Fathullah, M.; Shayfull, Z.; Nasir, S. M.; Hazwan, M. H. M.

    2017-09-01

    This paper presents a systematic methodology to analyse the warpage of the side arm part using Autodesk Moldflow Insight software. Response Surface Methodology (RSM) was proposed to optimise the processing parameters that will result in optimal solutions by efficiently minimising the warpage of the side arm part. The variable parameters considered in this study was based on most significant parameters affecting warpage stated by previous researchers, that is melt temperature, mould temperature and packing pressure while adding packing time and cooling time as these is the commonly used parameters by researchers. The results show that warpage was improved by 10.15% and the most significant parameters affecting warpage are packing pressure.

  9. Test and assessment method of Automotive Safety Systems (SSB) particularly to monitor traffic incidents

    Science.gov (United States)

    Pijanowski, B.; Łukjanow, S.; Burliński, R.

    2016-09-01

    The rapid development of telematics, particularly mobile telephony (GSM), wireless data transmission (GPRS) and satellite positioning (GPS) noticeable in the last decade, resulted in an almost unlimited growth of the possibilities for monitoring of mobile objects. These solutions are already widely used in the so-called “Intelligent Transport Systems” - ITS and affect a significant increase for road safety. The article describes a method of testing and evaluation of Car Safety Systems (Polish abbreviation - SSB) especially for monitoring traffic incidents, such as collisions and accidents. The algorithm of SSB testing process is also presented. Tests are performed on the dynamic test bench, part of which is movable platform with car security system mounted on it. Crash tests with a rigid obstacle are carried out instead of destructive attempts to crash test of the entire vehicle which is expensive. The tested system, depending on the simulated traffic conditions, is mounted in such a position and with the use of components, indicated by the manufacturer for the automotive safety system installation in a vehicle, for which it is intended. Then, the tests and assessments are carried out.

  10. Monitoring System For Improving Radiation Safety Management

    International Nuclear Information System (INIS)

    Osovizky, A.; Paran, J.; Tal, N.; Ankry, N.; Ashkenazi, B.; Tirosh, D.; Marziano, R.; Chisin, R.

    1999-01-01

    Medi SMARTS (Medical Survey Mapping Automatic Radiation Tracing System), a gamma radiation monitoring system, was installed in a nuclear medicine department. In this paper the evaluation of the system's ability to improve radiation safety management is presented. The system is based on a state of the art software that continuously collects on line radiation measurements for display, analysis and logging. Radiation is measured by GM tubes; the signal is transferred to a data processing unit and then via an RS-485 communication line to a computer. The system automatically identifies the detector type and its calibration factor, thus providing compatibility, maintainability and versatility when changing detectors. Radiation levels are displayed on the nuclear medicine department map at six locations. The system has been operating continuously for more than one year, documenting abnormal events caused by routine operation or failure incidents. In cases where abnormal working conditions were encountered, an alarm message was sent automatically to the supervisor via his tele-pager. An interesting issue observed during the system evaluation, was the inability to distinguish between high radiation levels caused by proper routine operation and those caused by safety failure incidents. The solution included examination of two parameters, radiation levels as well as their duration period. A careful analysis of the historical data, applying the appropriated combined parameters determined for each location, verified that such a system can identify abnormal events, provide alarms to warn in case of incidents and improve standard operating procedures

  11. Investigation and optimization of the novel UASB-MFC integrated system for sulfate removal and bioelectricity generation using the response surface methodology (RSM).

    Science.gov (United States)

    Zhang, Baogang; Zhang, Jing; Yang, Qi; Feng, Chuanping; Zhu, Yuling; Ye, Zhengfang; Ni, Jinren

    2012-11-01

    COD/sulfate ratio and hydraulic residence time (HRT), both of which influence sulfate loadings jointly, are recognized as the most two important affecting factors for sulfate removal and bioelectricity generation in the novel up-flow anaerobic sludge blanket reactor-microbial fuel cell (UASB-MFC) integrated system. The response surface methodology (RSM) was employed for the optimization of this system and the optimum condition with COD/sulfate ratio of 2.3 and HRT of 54.3h was obtained with the target of maximizing the power output. In terms of maximizing the total sulfate removal efficiency, the obtained optimum condition was COD/sulfate ratio of 3.7 and HRT of 55.6h. Experimental results indicated the undistorted simulation and reliable optimized results. These demonstrated that RSM was effective to evaluate and optimize the UASB-MFC system for sulfate removal and energy recovery, providing a promising guide to further improvement of the system for potential applications. Copyright © 2012 Elsevier Ltd. All rights reserved.

  12. Development and application of the San Onofre safety monitor

    International Nuclear Information System (INIS)

    Hook, Thomas G.; Lee, Roger J.; Morgan, Thomas A.

    2004-01-01

    Halliburton NUS Corporation (NUS) has developed a risk-based configuration management software tool for use at Southern California Edison's San Onofre Nuclear Generating Station. The software, called the Safety Monitor, calculates an estimate of current plant core damage risk based upon the plant's current operating configuration (e.g., equipment operability, system operating alignments). All data is entered and displayed in a format easily understood by plant personnel. The plant hopes to use this tool to ensure that risk is minimized during plant operations and to identify situations in which current Technical Specifications can be optimized. Plant configuration data and out-of-service time data is also automatically collected. (author)

  13. Optimization of process parameters of ECM by RSM on AISI 202 steel

    Directory of Open Access Journals (Sweden)

    P. Alex John Britto

    2015-12-01

    Full Text Available The machining of complex shaped designs was difficult earlier, but with the advent of the newer machining processes incorporating in it electrical, chemical & mechanical processes, manufacturing has redefined itself. Especially, the Electrochemical Machining (ECM process is used to machine the hard to cut materials without producing heat and friction. Hence, in this work, the ECM process has been chosen to machine SS AISI 202 steel. This study establishes the effect of process parameters such as voltage, current and concentration of electrolyte on the responses on material removal rate (MRR. In this work, second-order quadratic models were developed for MRR, considering the electrolyte concentration, voltage and current as the machining parameters, using central composite design. The developed models were used for Response Surface Methodology (RSM optimization by desirability function approach to determine the optimum machining parameters.

  14. Application of the Digital Image Technology in the Visual Monitoring and Prediction of Shuttering Construction Safety

    Science.gov (United States)

    Ummin, Okumura; Tian, Han; Zhu, Haiyu; Liu, Fuqiang

    2018-03-01

    Construction safety has always been the first priority in construction process. The common safety problem is the instability of the template support. In order to solve this problem, the digital image measurement technology has been contrived to support real-time monitoring system which can be triggered if the deformation value exceed the specified range. Thus the economic loss could be reduced to the lowest level.

  15. Lightweight monitoring and control system for coal mine safety using REST style.

    Science.gov (United States)

    Cheng, Bo; Cheng, Xin; Chen, Junliang

    2015-01-01

    The complex environment of a coal mine requires the underground environment, devices and miners to be constantly monitored to ensure safe coal production. However, existing coal mines do not meet these coverage requirements because blind spots occur when using a wired network. In this paper, we develop a Web-based, lightweight remote monitoring and control platform using a wireless sensor network (WSN) with the REST style to collect temperature, humidity and methane concentration data in a coal mine using sensor nodes. This platform also collects information on personnel positions inside the mine. We implement a RESTful application programming interface (API) that provides access to underground sensors and instruments through the Web such that underground coal mine physical devices can be easily interfaced to remote monitoring and control applications. We also implement three different scenarios for Web-based, lightweight remote monitoring and control of coal mine safety and measure and analyze the system performance. Finally, we present the conclusions from this study and discuss future work. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.

  16. Web of Things-Based Remote Monitoring System for Coal Mine Safety Using Wireless Sensor Network

    OpenAIRE

    Bo, Cheng; Xin, Cheng; Zhongyi, Zhai; Chengwen, Zhang; Junliang, Chen

    2014-01-01

    Frequent accidents have occurred in coal mine enterprises; therefore, raising the technological level of coal mine safety monitoring systems is an urgent problem. Wireless sensor networks (WSN), as a new field of research, have broad application prospects. This paper proposes a Web of Things- (WoT-) based remote monitoring system that takes full advantage of wireless sensor networks in combination with the CAN bus communication technique that abstracts the underground sensor data and capabili...

  17. Applications of ZigBee Technology in the Safety Monitoring System of Low Gas Pipeline Transportation

    Directory of Open Access Journals (Sweden)

    Wei Deyu

    2015-01-01

    Full Text Available The existing safety monitoring system of low gas pipeline transportation establishes a wired communication network monitoring system mainly on the basis of industrial bus. It has problems such as large transmission signal attenuation, complex wiring, high-labor intensity, inconvenient installation and maintenance, high maintenance cost, and so on. Featuring low cost, power-saving, reliability, stability and flexibility, the wireless sensor network established by ZigBee wireless communication technology can realize the real-time all-dimensional dynamic monitoring on parameters of low gas pipeline transportation system and overcome the shortcomings and deficiencies of wired network system.

  18. Catalogue of systems for the monitoring of working conditions relating to health and safety

    NARCIS (Netherlands)

    Prins, R.; Verboon, F.

    1991-01-01

    In this Catalogue a number of systems or instruments for Monitoring Working Conditions and workers Health and Safety have been described. The general aim of the project was three-fold: - to obtain an overall assessment of the existing instruments for identifying risk factors and working conditions

  19. Topical session proceedings of the 6. IGSC Meeting. The role of monitoring in a safety case

    International Nuclear Information System (INIS)

    2005-01-01

    This report summarises the outcomes of a topical session focused on the role of monitoring in a safety case. It was held as part of the 6. plenary meeting of the IGSC. It was attended by 39 participants, representing waste management organisations and regulatory authorities from 15 NEA member countries, the IAEA and the European Commission. The main purpose of this topical session was to create a platform for exchanging views on the key monitoring issues of interest to build confidence in a safety case e.g. relationship with the post-closure phase, functions, requirements, and to determine to what extent the main actions are to be addressed by the IGSC on its ongoing activities on defining the elements of a safety case. The topical session was indeed mainly aimed at exchanging information on: - National strategies or programmes in NEA members' countries. Member countries have organisations planning their own strategy, but some are already, to some extend engaged in implementing monitoring activities, e.g. Posiva Oy, US-DOE-YM, Andra. - Feedback from international projects, e.g. the EC Thematic Network on 'The role of Monitoring in a Phased Approach to Geological Disposal of Radioactive Waste', and the IAEA programme of work. - The expectations of regulators, e.g. SKI. Part A of this document summarises the material orally presented and provides the main lessons drawn from the presentations and the discussions that followed them. The overheads presented are compiled without any further elaboration by the NEA Secretariat as Part B of the document. Part C gives the list of participants. The document as a whole provides a synthesis of current issues in monitoring of a deep geological disposal facility

  20. The adaptive safety analysis and monitoring system

    Science.gov (United States)

    Tu, Haiying; Allanach, Jeffrey; Singh, Satnam; Pattipati, Krishna R.; Willett, Peter

    2004-09-01

    The Adaptive Safety Analysis and Monitoring (ASAM) system is a hybrid model-based software tool for assisting intelligence analysts to identify terrorist threats, to predict possible evolution of the terrorist activities, and to suggest strategies for countering terrorism. The ASAM system provides a distributed processing structure for gathering, sharing, understanding, and using information to assess and predict terrorist network states. In combination with counter-terrorist network models, it can also suggest feasible actions to inhibit potential terrorist threats. In this paper, we will introduce the architecture of the ASAM system, and discuss the hybrid modeling approach embedded in it, viz., Hidden Markov Models (HMMs) to detect and provide soft evidence on the states of terrorist network nodes based on partial and imperfect observations, and Bayesian networks (BNs) to integrate soft evidence from multiple HMMs. The functionality of the ASAM system is illustrated by way of application to the Indian Airlines Hijacking, as modeled from open sources.

  1. Development of Information Support of the Automated System for Monitoring the State of the Gas Transportation System’s Industrial Safety

    Directory of Open Access Journals (Sweden)

    Ruslan Skrynkovskyy

    2017-08-01

    Full Text Available The purpose of the article is to developing the information security of the automated system for monitoring the state of industrial safety of the gas transportation system within the framework of the safety management system, which will enable timely and objective detection of adverse accident hazards (hazardous events and taking the necessary specific measures to eliminate them and operate the gas transport system safely. It is proved that the basis of the information provision of the automated system for monitoring the state of the industrial safety of the gas transmission system is a methodology that includes the following basic procedures: identifying hazards; qualitative and quantitative assessment of emergencies; establishing of unacceptable (unallowable risks and their introduction to the information base (register of unacceptable risks of objects of the gas transportation system; comprehensive assessment and certification of the state of industrial safety of objects of the gas transportation system; identification of effective, productive (efficient risk management measures. The prospect of further research in this area is the development and implementation of an automated system for monitoring the state of industrial safety of the objects of the gas transmission system based on the results of the research (of the submitted information provision.

  2. Regulation of bacterial virulence by Csr (Rsm) systems.

    Science.gov (United States)

    Vakulskas, Christopher A; Potts, Anastasia H; Babitzke, Paul; Ahmer, Brian M M; Romeo, Tony

    2015-06-01

    Most bacterial pathogens have the remarkable ability to flourish in the external environment and in specialized host niches. This ability requires their metabolism, physiology, and virulence factors to be responsive to changes in their surroundings. It is no surprise that the underlying genetic circuitry that supports this adaptability is multilayered and exceedingly complex. Studies over the past 2 decades have established that the CsrA/RsmA proteins, global regulators of posttranscriptional gene expression, play important roles in the expression of virulence factors of numerous proteobacterial pathogens. To accomplish these tasks, CsrA binds to the 5' untranslated and/or early coding regions of mRNAs and alters translation, mRNA turnover, and/or transcript elongation. CsrA activity is regulated by noncoding small RNAs (sRNAs) that contain multiple CsrA binding sites, which permit them to sequester multiple CsrA homodimers away from mRNA targets. Environmental cues sensed by two-component signal transduction systems and other regulatory factors govern the expression of the CsrA-binding sRNAs and, ultimately, the effects of CsrA on secretion systems, surface molecules and biofilm formation, quorum sensing, motility, pigmentation, siderophore production, and phagocytic avoidance. This review presents the workings of the Csr system, the paradigm shift that it generated for understanding posttranscriptional regulation, and its roles in virulence networks of animal and plant pathogens. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  3. Measurement and monitoring of safety: impact and challenges of putting a conceptual framework into practice.

    Science.gov (United States)

    Chatburn, Eleanor; Macrae, Carl; Carthey, Jane; Vincent, Charles

    2018-03-06

    The Measurement and Monitoring of Safety Framework provides a conceptual model to guide organisations in assessing safety. The Health Foundation funded a large-scale programme to assess the value and impact of applying the Framework in regional and frontline care settings. We explored the experiences and reflections of key participants in the programme. The study was conducted in the nine healthcare organisations in England and Scotland testing the Framework (three regional improvement bodies, six frontline settings). Post hoc interviews with clinical and managerial staff were analysed using template analysis. Participants reported that the Framework promoted a substantial shift in their thinking about how safety is actively managed in their environment. It provided a common language, facilitated a more inquisitive approach and encouraged a more holistic view of the components of safety. These changes in conceptual understanding, however, did not always translate into broader changes in practice, with many sites only addressing some aspects of the Framework. One of the three regions did embrace the Framework in its entirety and achieved wider impact with a range of interventions. This region had committed leaders who took time to fully understand the concepts, who maintained a flexible approach to exploring the utility of the Framework and who worked with frontline staff to translate the concepts for local settings. The Measuring and Monitoring of Safety Framework has the potential to support a broader and richer approach to organisational safety. Such a conceptually based initiative requires both committed leaders who themselves understand the concepts and more time to establish understanding and aims than might be needed in a standard improvement programme. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  4. Radiological safety system based on real-time tritium-in-air monitoring in room and effluents

    Energy Technology Data Exchange (ETDEWEB)

    Bidica, N.; Sofalca, N.; Balteanu, O.; Stefan, I. [National Institute of Cryogenics and Isotopes Technologies, Ramnicu Valcea (Romania)

    2006-07-01

    The conceptual design of the radiological safety system based on real time-in-air monitoring in room and effluents is intended to provide the maximum achievable safety level, basing no the ALARA concept. the capabilities of this system are not only to inform any time personnel about tritium in air concentration level, but it will be able to: initiate the shut down procedure and drain off the plant, as well to start the Air cleaning System when the tritium-in-air concentration exceed pre-established threshold; estimate tritium effective dose rate before starting an activity into the monitored area, or during this activity, or soon as the activity was finished; estimate tritium effective dose and instantly record and update individual effective doses, using a special computer application called 'dose record'; lock access into the radiological area for individuals when tritium dose rate in the monitoring area will exceed the pre-established thresholds, or when any individual dose data provided by 'dose records' application ask for, or for other protection consideration; calculate the total tritium activity released to the environment (per day, week, or month). (N.C.)

  5. Radiological safety system based on real-time tritium-in-air monitoring in room and effluents

    International Nuclear Information System (INIS)

    Bidica, N.; Sofalca, N.; Balteanu, O.; Stefan, I.

    2006-01-01

    The conceptual design of the radiological safety system based on real time-in-air monitoring in room and effluents is intended to provide the maximum achievable safety level, basing no the ALARA concept. the capabilities of this system are not only to inform any time personnel about tritium in air concentration level, but it will be able to: initiate the shut down procedure and drain off the plant, as well to start the Air cleaning System when the tritium-in-air concentration exceed pre-established threshold; estimate tritium effective dose rate before starting an activity into the monitored area, or during this activity, or soon as the activity was finished; estimate tritium effective dose and instantly record and update individual effective doses, using a special computer application called 'dose record'; lock access into the radiological area for individuals when tritium dose rate in the monitoring area will exceed the pre-established thresholds, or when any individual dose data provided by 'dose records' application ask for, or for other protection consideration; calculate the total tritium activity released to the environment (per day, week, or month). (N.C.)

  6. Safety Evaluation of an Automated Remote Monitoring System for Heart Failure in an Urban, Indigent Population.

    Science.gov (United States)

    Gross-Schulman, Sandra; Sklaroff, Laura Myerchin; Hertz, Crystal Coyazo; Guterman, Jeffrey J

    2017-12-01

    Heart Failure (HF) is the most expensive preventable condition, regardless of patient ethnicity, race, socioeconomic status, sex, and insurance status. Remote telemonitoring with timely outpatient care can significantly reduce avoidable HF hospitalizations. Human outreach, the traditional method used for remote monitoring, is effective but costly. Automated systems can potentially provide positive clinical, fiscal, and satisfaction outcomes in chronic disease monitoring. The authors implemented a telephonic HF automated remote monitoring system that utilizes deterministic decision tree logic to identify patients who are at risk of clinical decompensation. This safety study evaluated the degree of clinical concordance between the automated system and traditional human monitoring. This study focused on a broad underserved population and demonstrated a safe, reliable, and inexpensive method of monitoring patients with HF.

  7. Configuration of risk monitor system by plant defense-in-depth risk monitor and reliability monitor

    International Nuclear Information System (INIS)

    Yoshikawa, Hidekazu; Lind Morten; Yang Ming; Hashim Muhammad; Zhang Zhijian

    2012-01-01

    A new method of risk monitor system of a nuclear power plant has been proposed from the aspect by what degree of safety functions incorporated in the plant system is maintained by multiple barriers of defense-in-depth (DiD). Wherein, the central idea is plant DiD risk monitor and reliability monitor derived from the five aspects of (1) design principle of nuclear safety based on DiD concept, (2) definition of risk and risk to be monitored, (3) severe accident phenomena as major risk, (4) scheme of risk ranking, and (5) dynamic risk display. In this paper, the overall frame of the proposed risk monitor system is summarized and the detailed discussion is made on major items such as definition of risk and risk ranking, anatomy of fault occurrence, two-layer configuration of risk monitor, how to configure individual elements of plant DiD risk monitor, and lastly how to apply for a PWR safety system. (author)

  8. Overcoming regulatory challenges in the development of companion diagnostics for monitoring and safety.

    Science.gov (United States)

    Shimazawa, Rumiko; Ikeda, Masayuki

    2016-03-01

    Concurrent development and co-approval of a companion diagnostic (CDx) with a corresponding drug is ideal, but often unfeasible. Because of limited exposure to a drug in clinical trials, crucial information on safety is sometimes revealed only after approval. Therefore, a CDx for monitoring/safety is often developed after approval of a corresponding drug. However, regulatory guidance is insufficient if contemporaneous development is not possible, thereby leaving plenty of opportunities for improvement with respect to pharmacovigilance and retrospective validation of the CDx. Furthermore, global harmonization of guidance on how to incorporate new scientific information from retrospective analyses of biomarkers should lead to the establishment of more evidence for the development of CDx for approved drugs.

  9. Assessment of the global trigger tool to measure, monitor and evaluate pateint safety in cancer patients

    DEFF Research Database (Denmark)

    Otto Mattsson, Thea; Lehmann-Knudsen, Janne; Lauritsen, Jens M

    2013-01-01

    BACKGROUND: Countries around the world are currently aiming to improve patient safety by means of the Institute for Healthcare Improvement global trigger tool (GTT), which is considered a valid tool for evaluating and measuring patient safety within organisations. So far, only few data....... RESULTS: Only 31% of adverse events (AE) were identified by both teams, and further differences in categorisation of identical events was found. Moderate interrater agreement (κ=0.45) between teams gave rise to different conclusions on the patient safety process when monitoring using SPC charts. The Bland......-Altman plot suggests little systematic error but large random error. CONCLUSIONS: Review teams may identify different AE and reach different conclusions on the safety process when using the GTT on identical charts. Tracking true change in the safety level is difficult due to measurement error of the GTT...

  10. Systems for the monitoring of working conditions relating to health and safety : extensive descriptions : Belgium, Germany, Luxembourg, The Netherlands

    NARCIS (Netherlands)

    Prins, R.; Verboon, F.

    1991-01-01

    This report contains the extensive descriptions of (some of) the monitoring systems on health and safety in use in the Benelux countries and Germany. The project of which this report is a part aimed at gathering information on monitoring systems throughout the EC member states.

  11. Application of response surface methodology (RSM) and genetic algorithm in minimizing warpage on side arm

    Science.gov (United States)

    Raimee, N. A.; Fathullah, M.; Shayfull, Z.; Nasir, S. M.; Hazwan, M. H. M.

    2017-09-01

    The plastic injection moulding process produces large numbers of parts of high quality with great accuracy and quickly. It has widely used for production of plastic part with various shapes and geometries. Side arm is one of the product using injection moulding to manufacture it. However, there are some difficulties in adjusting the parameter variables which are mould temperature, melt temperature, packing pressure, packing time and cooling time as there are warpage happen at the tip part of side arm. Therefore, the work reported herein is about minimizing warpage on side arm product by optimizing the process parameter using Response Surface Methodology (RSM) and with additional artificial intelligence (AI) method which is Genetic Algorithm (GA).

  12. Release of Radioactive Scrap Metal/Scrap Metal (RSM/SM) at Nevada Test Site (NTS)

    International Nuclear Information System (INIS)

    1993-01-01

    Reynolds Electrical and Engineering Company, Inc. (REECo) is the prime contractor to the US Department of Energy (DOE) in providing service and support for NTS operations. Mercury Base Camp is the main control point for the many forward areas at NTS, which covers 1,350 square miles. The forward areas are where above-ground and underground nuclear tests have been performed over the last 41 years. No metal (or other material) is returned to Mercury without first being tested for radioactivity. No radioactive metals are allowed to reenter Mercury from the forward areas, other than testing equipment. RAMATROL is the monitor check point. They check material in various ways, including swipe tests, and have a large assortment of equipment for testing. Scrap metal is also checked to address Resource Conservation and Recovery Act concerns. After addressing these issues, the scrap metals are categorized. Federal Property Management Regulations (FPMR) are followed by REECo. The nonradioactive scrap material is sold through the GSA on a scheduled basis. Radioactive scrap metal are presently held in forward areas where they were used. REECo has gained approval of their Nevada Test Site Defense Waste Acceptance Criteria, Certification, and Transfer Requirements, NVO-325 application, which will allow disposal on site, when RSM is declared a waste. The guideline that REECo uses for release limits is DOE Order 5480.11, Radiation Protection for Occupational Works, Attachment 2, Surface Radioactivity Guides, of this order, give release limits for radioactive materials. However, the removal of radioactive materials from NTS require approval by DOE Nevada Operations Office (DOE/NV) on a case-by-case basis. Requirements to consider before removal are found in DOE Order 5820.2A, Radioactive Waste Management

  13. The Trk Potassium Transporter Is Required for RsmB-Mediated Activation of Virulence in the Phytopathogen Pectobacterium wasabiae

    OpenAIRE

    Valente, Rita S.; Xavier, Karina B.

    2015-01-01

    Pectobacterium wasabiae (previously known as Erwinia carotovora) is an important plant pathogen that regulates the production of plant cell wall-degrading enzymes through an N-acyl homoserine lactone-based quorum sensing system and through the GacS/GacA two-component system (also known as ExpS/ExpA). At high cell density, activation of GacS/GacA induces the expression of RsmB, a noncoding RNA that is essential for the activation of virulence in this bacterium. A genetic screen to identify reg...

  14. Ward based community road safety performance benchmarking, monitoring and intervention programmes in the City of Johannesburg

    CSIR Research Space (South Africa)

    Ribbens, H

    2008-07-01

    Full Text Available benchmarking, monitoring and intervention programme. Community road safety needs in the respective wards are articulated through the ward councillor. The rationale is that the community exactly knows where these problem areas are, because they suffer as a...

  15. Drug Safety

    Science.gov (United States)

    ... over-the-counter drug. The FDA evaluates the safety of a drug by looking at Side effects ... clinical trials The FDA also monitors a drug's safety after approval. For you, drug safety means buying ...

  16. Office Visits to Monitor Stimulant Medication Safety and Efficacy: Recommended Care.

    Science.gov (United States)

    Zima, Bonnie T; Norquist, Grayson S; Altchuler, Steven I; Behrens, Jacob; Iles-Shih, Matthew D; Ng, Yiu Kee Warren; Schaepper, Mary Ann

    2018-06-01

    The clinical guidance based on the research article, "Specific Components of Pediatricians' Medication-Related Care Predict Attention-Deficit/Hyperactivity Disorder Improvement," published in the June 2017 issue, 1 might be premature. The authors, Epstein et al., suggest that "Physicians do not need to necessarily rely on office visits to monitor medication response and side effects in the week(s) after initially prescribing medication, but instead could use phone calls or email correspondence to check in with the family" (p. 489). However, this advice has the potential to be misinterpreted that phone or email contact is acceptable clinical practice to monitor stimulant medication safety and efficacy, especially during the maintenance phase. It also could be erroneously interpreted that phone or email contact is sufficient for follow-up care for children receiving medication treatment for attention-deficit/hyperactivity disorder (ADHD) for national quality measures. Copyright © 2018 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.

  17. Indicators of safety culture - selection and utilization of leading safety performance indicators

    Energy Technology Data Exchange (ETDEWEB)

    Reiman, Teemu; Pietikaeinen, Elina (VTT, Technical Research Centre of Finland (Finland))

    2010-03-15

    Safety indicators play a role in providing information on organizational performance, motivating people to work on safety and increasing organizational potential for safety. The aim of this report is to provide an overview on leading safety indicators in the domain of nuclear safety. The report explains the distinction between lead and lag indicators and proposes a framework of three types of safety performance indicators - feedback, monitor and drive indicators. Finally the report provides guidance for nuclear energy organizations for selecting and interpreting safety indicators. It proposes the use of safety culture as a leading safety performance indicator and offers an example list of potential indicators in all three categories. The report concludes that monitor and drive indicators are so called lead indicators. Drive indicators are chosen priority areas of organizational safety activity. They are based on the underlying safety model and potential safety activities and safety policy derived from it. Drive indicators influence control measures that manage the socio technical system; change, maintain, reinforce, or reduce something. Monitor indicators provide a view on the dynamics of the system in question; the activities taking place, abilities, skills and motivation of the personnel, routines and practices - the organizational potential for safety. They also monitor the efficacy of the control measures that are used to manage the socio technical system. Typically the safety performance indicators that are used are lagging (feedback) indicators that measure the outcomes of the socio technical system. Besides feedback indicators, organizations should also acknowledge the important role of monitor and drive indicators in managing safety. The selection and use of safety performance indicators is always based on an understanding (a model) of the socio technical system and safety. The safety model defines what risks are perceived. It is important that the safety

  18. Indicators of safety culture - selection and utilization of leading safety performance indicators

    International Nuclear Information System (INIS)

    Reiman, Teemu; Pietikaeinen, Elina

    2010-03-01

    Safety indicators play a role in providing information on organizational performance, motivating people to work on safety and increasing organizational potential for safety. The aim of this report is to provide an overview on leading safety indicators in the domain of nuclear safety. The report explains the distinction between lead and lag indicators and proposes a framework of three types of safety performance indicators - feedback, monitor and drive indicators. Finally the report provides guidance for nuclear energy organizations for selecting and interpreting safety indicators. It proposes the use of safety culture as a leading safety performance indicator and offers an example list of potential indicators in all three categories. The report concludes that monitor and drive indicators are so called lead indicators. Drive indicators are chosen priority areas of organizational safety activity. They are based on the underlying safety model and potential safety activities and safety policy derived from it. Drive indicators influence control measures that manage the socio technical system; change, maintain, reinforce, or reduce something. Monitor indicators provide a view on the dynamics of the system in question; the activities taking place, abilities, skills and motivation of the personnel, routines and practices - the organizational potential for safety. They also monitor the efficacy of the control measures that are used to manage the socio technical system. Typically the safety performance indicators that are used are lagging (feedback) indicators that measure the outcomes of the socio technical system. Besides feedback indicators, organizations should also acknowledge the important role of monitor and drive indicators in managing safety. The selection and use of safety performance indicators is always based on an understanding (a model) of the socio technical system and safety. The safety model defines what risks are perceived. It is important that the safety

  19. The challenges in monitoring and preventing patient safety incidents for people with intellectual disabilities in NHS acute hospitals: evidence from a mixed-methods study.

    Science.gov (United States)

    Tuffrey-Wijne, Irene; Goulding, Lucy; Gordon, Vanessa; Abraham, Elisabeth; Giatras, Nikoletta; Edwards, Christine; Gillard, Steve; Hollins, Sheila

    2014-09-24

    There has been evidence in recent years that people with intellectual disabilities in acute hospitals are at risk of preventable deterioration due to failures of the healthcare services to implement the reasonable adjustments they need. The aim of this paper is to explore the challenges in monitoring and preventing patient safety incidents involving people with intellectual disabilities, to describe patient safety issues faced by patients with intellectual disabilities in NHS acute hospitals, and investigate underlying contributory factors. This was a 21-month mixed-method study involving interviews, questionnaires, observation and monitoring of incident reports to assess the implementation of recommendations designed to improve care provided for patients with intellectual disabilities and explore the factors that compromise or promote patient safety. Six acute NHS Trusts in England took part. Data collection included: questionnaires to clinical hospital staff (n = 990); questionnaires to carers (n = 88); interviews with: hospital staff including senior managers, nurses and doctors (n = 68) and carers (n = 37); observation of in-patients with intellectual disabilities (n = 8); monitoring of incident reports (n = 272) and complaints involving people with intellectual disabilities. Staff did not always readily identify patient safety issues or report them. Incident reports focused mostly around events causing immediate or potential physical harm, such as falls. Hospitals lacked effective systems for identifying patients with intellectual disabilities within their service, making monitoring safety incidents for this group difficult.The safety issues described by the participants were mostly related to delays and omissions of care, in particular: inadequate provision of basic nursing care, misdiagnosis, delayed investigations and treatment, and non-treatment decisions and Do Not Attempt Cardiopulmonary Resuscitation (DNACPR) orders. The events leading to avoidable harm

  20. Radiation Safety in Industrial Radiography. Specific Safety Guide

    International Nuclear Information System (INIS)

    2011-01-01

    This Safety Guide provides recommendations for ensuring radiation safety in industrial radiography used in non-destructive testing. This includes industrial radiography work that utilizes X ray and gamma sources, both in shielded facilities that have effective engineering controls and in outside shielded facilities using mobile sources. Contents: 1. Introduction; 2. Duties and responsibilities; 3. Safety assessment; 4. Radiation protection programme; 5. Training and qualification; 6. Individual monitoring of workers; 7. Workplace monitoring; 8. Control of radioactive sources; 9. Safety of industrial radiography sources and exposure devices; 10. Radiography in shielded enclosures; 11. Site radiography; 12. Transport of radioactive sources; 13. Emergency preparedness and response; Appendix: IAEA categorization of radioactive sources; Annex I: Example safety assessment; Annex II: Overview of industrial radiography sources and equipment; Annex III: Examples of accidents in industrial radiography.

  1. ASIC-based design of NMR system health monitor for mission/safety-critical applications.

    Science.gov (United States)

    Balasubramanian, P

    2016-01-01

    N-modular redundancy (NMR) is a generic fault tolerance scheme that is widely used in safety-critical circuit/system designs to guarantee the correct operation with enhanced reliability. In passive NMR, at least a majority (N + 1)/2 out of N function modules is expected to operate correctly at any time, where N is odd. Apart from a conventional realization of the NMR system, it would be useful to provide a concurrent indication of the system's health so that an appropriate remedial action may be initiated depending upon an application's safety criticality. In this context, this article presents the novel design of a generic NMR system health monitor which features: (i) early fault warning logic, that is activated upon the production of a conflicting result by even one output of any arbitrary function module, and (ii) error signalling logic, which signals an error when the number of faulty function modules unfortunately attains a majority and the system outputs may no more be reliable. Two sample implementations of NMR systems viz. triple modular redundancy and quintuple modular redundancy with the proposed system health monitoring are presented in this work, with a 4-bit ALU used for the function modules. The simulations are performed using a 32/28 nm CMOS process technology.

  2. Initial Demonstration of the Real-Time Safety Monitoring Framework for the National Airspace System Using Flight Data

    Science.gov (United States)

    Roychoudhury, Indranil; Daigle, Matthew; Goebel, Kai; Spirkovska, Lilly; Sankararaman, Shankar; Ossenfort, John; Kulkarni, Chetan; McDermott, William; Poll, Scott

    2016-01-01

    As new operational paradigms and additional aircraft are being introduced into the National Airspace System (NAS), maintaining safety in such a rapidly growing environment becomes more challenging. It is therefore desirable to have an automated framework to provide an overview of the current safety of the airspace at different levels of granularity, as well an understanding of how the state of the safety will evolve into the future given the anticipated flight plans, weather forecast, predicted health of assets in the airspace, and so on. Towards this end, as part of our earlier work, we formulated the Real-Time Safety Monitoring (RTSM) framework for monitoring and predicting the state of safety and to predict unsafe events. In our previous work, the RTSM framework was demonstrated in simulation on three different constructed scenarios. In this paper, we further develop the framework and demonstrate it on real flight data from multiple data sources. Specifically, the flight data is obtained through the Shadow Mode Assessment using Realistic Technologies for the National Airspace System (SMART-NAS) Testbed that serves as a central point of collection, integration, and access of information from these different data sources. By testing and evaluating using real-world scenarios, we may accelerate the acceptance of the RTSM framework towards deployment. In this paper we demonstrate the framework's capability to not only estimate the state of safety in the NAS, but predict the time and location of unsafe events such as a loss of separation between two aircraft, or an aircraft encountering convective weather. The experimental results highlight the capability of the approach, and the kind of information that can be provided to operators to improve their situational awareness in the context of safety.

  3. Diagnosis function of safety status in the safety parameter display system (SPDS)

    International Nuclear Information System (INIS)

    Zhang Yuanfang

    1993-04-01

    An automatic diagnosis function of safety status for nuclear power plant adopted in the SPDS is introduced. To guarantee diagnosis diversification, two diagnosis criteria of a design basis accident monitoring and a critical safety function monitoring used in plant emergency operation are provided. As an extensive function, a parameter deviation monitoring used in plant normal operation is also provided

  4. An Online Risk Monitor System (ORMS) to Increase Safety and Security Levels in Industry

    International Nuclear Information System (INIS)

    Zubair, M; Ur Rahman, Khalil; Ul Hassan, Mehmood

    2013-01-01

    The main idea of this research is to develop an Online Risk Monitor System (ORMS) based on Living Probabilistic Safety Assessment (LPSA). The article highlights the essential features and functions of ORMS. The basic models and modules such as, Reliability Data Update Model (RDUM), running time update, redundant system unavailability update, Engineered Safety Features (ESF) unavailability update and general system update have been described in this study. ORMS not only provides quantitative analysis but also highlights qualitative aspects of risk measures. ORMS is capable of automatically updating the online risk models and reliability parameters of equipment. ORMS can support in the decision making process of operators and managers in Nuclear Power Plants

  5. An Online Risk Monitor System (ORMS) to Increase Safety and Security Levels in Industry

    Science.gov (United States)

    Zubair, M.; Rahman, Khalil Ur; Hassan, Mehmood Ul

    2013-12-01

    The main idea of this research is to develop an Online Risk Monitor System (ORMS) based on Living Probabilistic Safety Assessment (LPSA). The article highlights the essential features and functions of ORMS. The basic models and modules such as, Reliability Data Update Model (RDUM), running time update, redundant system unavailability update, Engineered Safety Features (ESF) unavailability update and general system update have been described in this study. ORMS not only provides quantitative analysis but also highlights qualitative aspects of risk measures. ORMS is capable of automatically updating the online risk models and reliability parameters of equipment. ORMS can support in the decision making process of operators and managers in Nuclear Power Plants.

  6. Real-time environmental monitoring at the Japan Nuclear Cycle Development Institute O-arai Engineering Center. Using the internet to promote safety and environmental transparency

    International Nuclear Information System (INIS)

    Motomatsu, Sheila; Nakashima Inoue, Naoko

    2000-12-01

    The report documents the results of an effort at the Japan Nuclear Cycle Development Institute O-arai Engineering Center (JNC/OEC) to provide via the Internet, in real-time, environmental monitoring data to promote safety and environmental transparency. Provided in Japanese as well as in English, the Internet site provides assurance that OEC nuclear operations are being conducted in a manner that is safe to both people in the surrounding area and the environment. This work conducted by Environmental Monitoring Team of the OEC Safety Administration Section fulfilled the assignment to release data real-time via the Internet tasked by the Information Disclosure Section of the JNC Headquarters Public Relations Division. The work conducted by the visiting exchange scientist fulfilled the experimental portion of Action Sheet 34 of the Agreement between JNC and DOE for Cooperation in Research and Development Concerning Nuclear Material Control and Accounting Measures for Safeguards and Nonproliferation. In Japan, the project for Action Sheet 34 Personnel Exchange on Remote Monitoring and Transparency' entailed both a study and an experiment on how remote monitoring technologies can be used to promote nonproliferation, environmental and safety transparency. Environmental airborne radionuclide monitoring falls under the definition of remote monitoring technology more broadly defined as 'remotely accessed unattended monitoring system technology'. (author)

  7. Development of a web based monitoring system for safety and activity analysis in operating theatres.

    Science.gov (United States)

    Frosini, Francesco; Miniati, Roberto; Avezzano, Paolo; Cecconi, Giulio; Dori, Fabrizio; Gentili, Guido Biffi; Belardinelli, Andrea

    2016-01-01

    The management and the monitoring of the operating rooms on the part of the general management have the objective of optimizing their use and maximizing the internal safety. The expenses owed to their safe use represent, besides reimbursements coming from the surgical activity, important factors for the analysis of the medical facility. Given that it is not possible to reduce the safety, it is necessary to develop supporting systems with the aim to enhance and optimize the use of the rooms. The developed analysis model of the operating rooms in this study is based on the specific performance indicators and allows the effective monitoring of both the parameters that influence the safety (environmental, microbiological parameters) and those that influence the efficiency of the usage (employment rate, delays, necessary formalities, etc.). This allows you to have a systematic dashboard on hand for all of the OTs and, thus, organize the intervention schedules and more appropriate improvements. A monitoring dashboard has been achieved, accessible from any platform and any device, capable of aggregating hospital information. The undertaken organizational modifications, through the use of the dashboard, have allowed for an average annual savings of 29.52 minutes per intervention and increase the use of the ORs of 5%. The increment of the employment rate and the optimization of the operating room have allowed for savings of around $299,88 for every intervention carried out in 2013, corresponding to an annual savings of $343,362,60. Integration dashboards, as the one proposed in this study as a prototype, represent a governance model of economically sustainable healthcare systems capable of guiding the hospital management in the choices and in the implementation of the most efficient organizational modifications.

  8. On-line generation of three-dimensional core power distribution using incore detector signals to monitor safety limits

    International Nuclear Information System (INIS)

    Jang, Jin Wook; Lee, Ki Bog; Na, Man Gyun; Lee, Yoon Joon

    2004-01-01

    It is essential in commercial reactors that the safety limits imposed on the fuel pellets and fuel clad barriers, such as the Linear Power Density (LPD) and the Departure from Nucleate Boiling Ratio (DNBR), are not violated during reactor operations. In order to accurately monitor the safety limits of current reactor states, a detailed three-dimensional (3D) core power distribution should be estimated from the in-core detector signals. In this paper, we propose a calculation methodology for detailed 3D core power distribution, using in-core detector signals and core monitoring constants such as the 3D Coupling Coefficients (3DCC), node power fraction, and pin-to-node factors. Also, the calculation method for several core safety parameters is introduced. The core monitoring constants for the real core state are promptly provided by the core design code and on-line MASTER(Multi-purpose Analyzer for Static and Transient Effects of Reactors), coupled with the core monitoring program. Through the plant computer, core state variables, which include reactor thermal power, control rod bank position, boron concentration, inlet moderator temperature, and flow rate, are supplied as input data for MASTER. MASTER performs the core calculation based on the neutron balance equation and generates several core monitoring constants corresponding to the real core state in addition to the expected core power distribution. The accuracy of the developed method is verified through a comparison with the current CECOR method. Because in all the verification calculation cases the proposed method shows a more conservative value than the best estimated value and a less conservative one than the current CECOR and COLSS methods, it is also confirmed that this method secures a greater operating margin through the simulation of the YGN-3 cycle-1 core from the viewpoint of the power peaking factor for the LPD and the pseudo hot pin axial power distribution for the DNBR calculation

  9. Biosynthesis of ergot alkaloids from penicillium commune using response surface methodology (RSM)

    International Nuclear Information System (INIS)

    Shahid, M. G.; Cheema, T. A.; Baig, S.; Nadeem, M.; Nelofar, R.

    2017-01-01

    The present study employed the response surface methodology (RSM), a statistical technique, for the identification, screening and optimization of fermentation factors to produce ergot alkaloids under laboratory conditions by Penicillium commune. The static surface culture fermentation technique helped to enhance the production of ergot alkaloids. In the first step Plackett-Burman design (PBD) was used to evaluate the effect of ten factors, including nine ingredients of fermentation medium and one process parameter. It was found that sucrose, yeast extract and FeSO/sub 4/.7H/sub 2/O played the pivotal role in enhancing the yield of ergot alkaloids. In the second step, the effect of concentration levels of sucrose, yeast extract and FeSO/sub 4/.7H/sub 2/O was further optimized using Box-Behnken design (BBD) under the same fermentation conditions. The optimized concentrations of sucrose, yeast extract and FeSO/sub 4/.7H/sub 2/O were 41%, 39% and 0.11% respectively, which significantly enhanced the yield of ergot alkaloids. (author)

  10. Principal components based support vector regression model for on-line instrument calibration monitoring in NPPs

    International Nuclear Information System (INIS)

    Seo, In Yong; Ha, Bok Nam; Lee, Sung Woo; Shin, Chang Hoon; Kim, Seong Jun

    2010-01-01

    In nuclear power plants (NPPs), periodic sensor calibrations are required to assure that sensors are operating correctly. By checking the sensor's operating status at every fuel outage, faulty sensors may remain undetected for periods of up to 24 months. Moreover, typically, only a few faulty sensors are found to be calibrated. For the safe operation of NPP and the reduction of unnecessary calibration, on-line instrument calibration monitoring is needed. In this study, principal component based auto-associative support vector regression (PCSVR) using response surface methodology (RSM) is proposed for the sensor signal validation of NPPs. This paper describes the design of a PCSVR-based sensor validation system for a power generation system. RSM is employed to determine the optimal values of SVR hyperparameters and is compared to the genetic algorithm (GA). The proposed PCSVR model is confirmed with the actual plant data of Kori Nuclear Power Plant Unit 3 and is compared with the Auto-Associative support vector regression (AASVR) and the auto-associative neural network (AANN) model. The auto-sensitivity of AASVR is improved by around six times by using a PCA, resulting in good detection of sensor drift. Compared to AANN, accuracy and cross-sensitivity are better while the auto-sensitivity is almost the same. Meanwhile, the proposed RSM for the optimization of the PCSVR algorithm performs even better in terms of accuracy, auto-sensitivity, and averaged maximum error, except in averaged RMS error, and this method is much more time efficient compared to the conventional GA method

  11. Examination of issues related to the development and implementation of real-time operational safety monitoring tools in the nuclear power industry

    International Nuclear Information System (INIS)

    Puglia, William J.; Atefi, Bahman

    1995-01-01

    In recent years, risk and reliability techniques have been increasingly used to optimize deterministic requirements and to improve the operational safety of nuclear power stations. This paper discusses the historical development and current status of implementation of real-time operational safety monitoring tools in the nuclear power industry worldwide. A safety monitor is defined as a PC-based risk management tool, based on a plant specific PSA, which can be used to manage plant safety during the day-to-day operation of a nuclear power plant by planning maintenance activities and providing advisory information to plant operational staff in order to avoid high risk plant configurations. As this technique has only been applied in a few plants worldwide, the technology is still evolving and there are several technical and implementation-related issues which still need to be resolved. This paper attempts to summarize all such issues and describe how they have been addressed in several different applications of this technology around the world

  12. Assessing Drinking Water Quality and Water Safety Management in Sub-Saharan Africa Using Regulated Monitoring Data.

    Science.gov (United States)

    Kumpel, Emily; Peletz, Rachel; Bonham, Mateyo; Khush, Ranjiv

    2016-10-18

    Universal access to safe drinking water is prioritized in the post-2015 Sustainable Development Goals. Collecting reliable and actionable water quality information in low-resource settings, however, is challenging, and little is known about the correspondence between water quality data collected by local monitoring agencies and global frameworks for water safety. Using 42 926 microbial water quality test results from 32 surveillance agencies and water suppliers in seven sub-Saharan African countries, we determined the degree to which water sources were monitored, how water quality varied by source type, and institutional responses to results. Sixty-four percent of the water samples were collected from piped supplies, although the majority of Africans rely on nonpiped sources. Piped supplies had the lowest levels of fecal indicator bacteria (FIB) compared to any other source type: only 4% of samples of water piped to plots and 2% of samples from water piped to public taps/standpipes were positive for FIB (n = 14 948 and n = 12 278, respectively). Among other types of improved sources, samples from harvested rainwater and boreholes were less often positive for FIB (22%, n = 167 and 31%, n = 3329, respectively) than protected springs or protected dug wells (39%, n = 472 and 65%, n = 505). When data from different settings were aggregated, the FIB levels in different source types broadly reflected the source-type water safety framework used by the Joint Monitoring Programme. However, the insufficient testing of nonpiped sources relative to their use indicates important gaps in current assessments. Our results emphasize the importance of local data collection for water safety management and measurement of progress toward universal safe drinking water access.

  13. Design and research of safety monitor and control system based on CAN BUS

    International Nuclear Information System (INIS)

    Wen Xinling; Chen Yu; Zhang Zhen; Zhao Yubin

    2007-01-01

    In Order to protect machine operator under danger work area in producing-manufacturing industry, we present a distributed safety monitor and control system based on CAN BUS technology. The detection signal is collected based on the photo-voltage characteristics of the infrared sensor and it was processed with the core of AT89C51. The microprocessor controls the CAN BUS controller SJA1000/transceiver PCA82C250 to structure CAN BUS communication system to transmit the data. Through the serial interface MAX232 connected main controller with each control node, PC can monitor and control each machine in real time and renew control scheme. This paper introduces composition principle and the methods of hardware design in detail. Experiments shown that the system has yield control precision of 0.1 mm, defend distance more than 15 m and the measurement accuracy of 100%. Moreover, it can realize to reform FA431 and monitor cotton-breaking, yarn-breaking and product quality. Productivity is improved about 25%-35%. (authors)

  14. Safety analysis report: A comparison of incidents from Safety Years 2006 through 2010, USDA Forest Service, Rocky Mountain Research Station Inventory and Monitoring Program

    Science.gov (United States)

    Devon Donahue

    2012-01-01

    This paper is an analysis of 5 years of accident data for the USDA Forest Service, Rocky Mountain Research Station (RMRS) Inventory and Monitoring (IM) Program that identifies past trends, allows for standardized self-comparison, and increases our understanding of the true costs of injuries and accidents. Measuring safety is a difficult task. While most agree that...

  15. Configuration of Risk Monitor System by PLant Defense-In.Depth Monitor and Relability Monitor

    DEFF Research Database (Denmark)

    Yoshikawa, Hidekazu; Lind, Morten; Yang, Ming

    2012-01-01

    A new method of risk monitor system of a nuclear power plant has been proposed from the aspect by what degree of safety functions incorporated in the plant system is maintained by multiple barriers of defense-in-depth (DiD). Wherein, the central idea is plant DiD risk monitor and reliability...... monitor derived from the four aspects of (i) design principle of nuclear safety to realize DiD concept, (ii) definition of risk and risk to be monitored, (iii) severe accident phenomena as major risk, (iv) scheme of risk ranking, and (v) dynamic risk display. In this paper, the overall frame...... of the proposed frame on risk monitor system is summarized and the detailed discussion is made on the definitions of major terminologies of risk, risk ranking, anatomy of fault occurrence, two-layer configuration of risk monitor, how to configure individual elements of plant DiD risk monitor and its example...

  16. Rule-based Dynamic Safety Monitoring for Mobile Robots

    DEFF Research Database (Denmark)

    Adam, Marian Sorin; Larsen, Morten; Jensen, Kjeld

    2016-01-01

    Safety is a key challenge in robotics, in particular for mobile robots operating in an open and unpredictable environment. Safety certification is desired for commercial robots, but no existing approaches for addressing the safety challenge provide a clearly specified and isolated safety layer......, defined in an easily understandable way for facilitating safety certification. In this paper, we propose that functional-safety-critical concerns regarding the robot software be explicitly declared separately from the main program, in terms of externally observable properties of the software. Concretely...

  17. Using Chitosan/CHPATC as coagulant to remove color and turbidity of industrial wastewater: Optimization through RSM design.

    Science.gov (United States)

    Momeni, Meysam Mohammad; Kahforoushan, Davood; Abbasi, Farhang; Ghanbarian, Saeid

    2018-04-01

    One of the most important solid-liquid separation processes is coagulation and flocculation that is extensively used in the primary treatment of industrial wastewater. The biopolymers, because of biodegradable properties and low cost have been used as coagulants. In this study, chitosan as a natural coagulant of choice, was modified by (3-chloro 2-hydroxypropyl)trimethylammonium chloride and was used to remove the color and turbidity of industrial wastewater. To evaluate the effect of pH, settling time, the initial turbidity of wastewater, the amount of coagulant, and the concentration of dye (Melanoidin) were chosen to study their effects on removal of wastewater color and turbidity. The experiments were done in a batch system by using a jar test. To achieve the optimum conditions for the removal of color and turbidity, the response surface methodology (RSM) experimental design method was used. The results obtained from experiments showed that the optimum conditions for the removal of color were as: pH = 3, concentration of dye = 1000 mg/L, settling time = 78.93 min, and dose of coagulant = 3 g/L. The maximum color removal in these conditions was predicted 82.78% by the RSM model. The optimal conditions for the removal of turbidity of the waste water were as: pH = 5.66, initial turbidity = 60 NTU, settling time = 105 min, and amount of coagulant = 3 g/L. The maximum turbidity removal in these circumstances was predicted 94.19% by the model. The experimental results obtained in optimum conditions for removal of color and turbidity were 76.20% and 90.14%, respectively, indicating the high accuracy of the prediction model. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. Barnehagestyreres opplevelser av forholdet til skolen i spørsmål om barns læring

    Directory of Open Access Journals (Sweden)

    Kari Hoås Moen

    2017-03-01

    Full Text Available This study draws attention to what extent directors of private and municipal Early Childhood Centers (ECCs experience disagreement with school concerning questions about children’s learning in ECCs and the content of this disagreement. Furthermore, it focuses to what extent the directors of these two center categories try to influence school in such questions, and how they possibly may do this. The material derives from a nationwide survey (1310 directors and an interview study (16 directors. The directors experience disagreements to a small extent and least in private centers. However, some disagree about to which extent the adults should lead children’s learning. This study reveals a great variety in how much the directors try to influence school. The municipal directors are most active. Artikkelen retter søkelys på i hvilken grad styrere i kommunale og private barnehager opplever uenighet med skolen i spørsmål om barns læring i barnehagen og eventuelt hva slik uenighet kan handle om. Videre ser den på i hvilken grad styrere i de to barnehagetypene forsøker å påvirke skolen i spørsmål om barns læring og eventuelt på hvilke måter. Datamaterialet kommer fra en landsdekkende survey (1310 styrere og intervjuundersøkelse (16 styrere. Styrerne opplever liten grad av uenighet med skolen og minst i private barnehager. Et tema det kan være uenighet om, er grad av voksenstyring i læringsaktivitetene. Det er stor spredning på i hvilken grad styrerne forsøker å påvirke skolen. Styrere i kommunale barnehager er klart mest aktive. Styrerne forsøker å påvirke skolen på ulike måter.

  19. Road Safety Data, Collection, Transfer and Analysis DaCoTa. Workpackage 6, Driver Behaviour Monitoring through Naturalistic Driving: Deliverable 6.3: Report on small scale naturalistic driving pilot.

    NARCIS (Netherlands)

    Pilgerstorfer, M. Runda, K. Brandstätter, C. Christoph, M. Hakkert, S. Ishaq, R. Toledo, T. & Gatscha, M.

    2012-01-01

    WP6 of DaCoTA, Driver Behaviour Monitoring through Naturalistic Driving, aims to develop an implementation plan for a large scale activity that uses Naturalistic Driving (ND) Observations to continuously monitor relevant road safety data within the framework of the European Road Safety Observatory.

  20. Radiation Safety in Industrial Radiography. Specific Safety Guide (Spanish Edition)

    International Nuclear Information System (INIS)

    2013-01-01

    This Safety Guide provides recommendations for ensuring radiation safety in industrial radiography used in non-destructive testing. This includes industrial radiography work that utilizes X ray and gamma sources, both in shielded facilities that have effective engineering controls and in outside shielded facilities using mobile sources. Contents: 1. Introduction; 2. Duties and responsibilities; 3. Safety assessment; 4. Radiation protection programme; 5. Training and qualification; 6. Individual monitoring of workers; 7. Workplace monitoring; 8. Control of radioactive sources; 9. Safety of industrial radiography sources and exposure devices; 10. Radiography in shielded enclosures; 11. Site radiography; 12. Transport of radioactive sources; 13. Emergency preparedness and response; Appendix: IAEA categorization of radioactive sources; Annex I: Example safety assessment; Annex II: Overview of industrial radiography sources and equipment; Annex III: Examples of accidents in industrial radiography

  1. Radiation Safety in Industrial Radiography. Specific Safety Guide (French Edition)

    International Nuclear Information System (INIS)

    2013-01-01

    This Safety Guide provides recommendations for ensuring radiation safety in industrial radiography used in non-destructive testing. This includes industrial radiography work that utilizes X ray and gamma sources, both in … shielded facilities that have effective engineering controls and in outside shielded facilities using mobile sources. Contents: 1. Introduction; 2. Duties and responsibilities; 3. Safety assessment; 4. Radiation protection programme; 5. Training and qualification; 6. Individual monitoring of workers; 7. Workplace monitoring; 8. Control of radioactive sources; 9. Safety of industrial radiography sources and exposure devices; 10. Radiography in shielded enclosures; 11. Site radiography; 12. Transport of radioactive sources; 13. Emergency preparedness and response; Appendix: IAEA categorization of radioactive sources; Annex I: Example safety assessment; Annex II: Overview of industrial radiography sources and equipment; Annex III: Examples of accidents in industrial radiography

  2. Radiation Safety in Industrial Radiography. Specific Safety Guide (Arabic Edition)

    International Nuclear Information System (INIS)

    2012-01-01

    This Safety Guide provides recommendations for ensuring radiation safety in industrial radiography used in non-destructive testing. This includes industrial radiography work that utilizes X ray and gamma sources, both in shielded facilities that have effective engineering controls and outside shielded facilities using mobile sources. Contents: 1. Introduction; 2. Duties and responsibilities; 3. Safety assessment; 4. Radiation protection programme; 5. Training and qualification; 6. Individual monitoring of workers; 7. Workplace monitoring; 8. Control of radioactive sources; 9. Safety of industrial radiography sources and exposure devices; 10. Radiography in shielded enclosures; 11. Site radiography; 12. Transport of radioactive sources; 13. Emergency preparedness and response; Appendix: IAEA categorization of radioactive sources; Annex I: Example safety assessment; Annex II: Overview of industrial radiography sources and equipment; Annex III: Examples of accidents in industrial radiography.

  3. The safety monitor and RCM workstation as complementary tools in risk based maintenance optimization

    International Nuclear Information System (INIS)

    Rawson, P.D.

    2000-01-01

    Reliability Centred Maintenance (RCM) represents a proven technique for rendering maintenance activities safer, more effective, and less expensive, in terms of systems unavailability and resource management. However, it is believed that RCM can be enhanced by the additional consideration of operational plant risk. This paper discusses how two computer-based tools, i.e., the RCM Workstation and the Safety Monitor, can complement each other in helping to create a living preventive maintenance strategy. (author)

  4. Utilizing data consortia to monitor safety and effectiveness of biosimilars and their innovator products.

    Science.gov (United States)

    Baldziki, Mike; Brown, Jeff; Chan, Hungching; Cheetham, T Craig; Conn, Thomas; Daniel, Gregory W; Hendrickson, Mark; Hilbrich, Lutz; Johnson, Ayanna; Miller, Steven B; Moore, Tom; Motheral, Brenda; Priddy, Sarah A; Raebel, Marsha A; Randhawa, Gurvaneet; Surratt, Penny; Walraven, Cheryl; White, T Jeff; Bruns, Kevin; Carden, Mary Jo; Dragovich, Charlie; Eichelberger, Bernadette; Rosato, Edith; Sega, Todd

    2015-01-01

    The Biologics Price Competition and Innovation Act, introduced as part of the Affordable Care Act, directed the FDA to create an approval pathway for biologic products shown to be biosimilar or interchangeable with an FDA-approved innovator drug. These biosimilars will not be chemically identical to the reference agent. Investigational studies conducted with biosimilar agents will likely provide limited real-world evidence of their effectiveness and safety. How do we best monitor effectiveness and safety of biosimilar products once approved by the FDA and used more extensively by patients? To determine the feasibility of developing a distributed research network that will use health insurance plan and health delivery system data to detect biosimilar safety and effectiveness signals early and be able to answer important managed care pharmacy questions from both the government and managed care organizations. Twenty-one members of the AMCP Task Force on Biosimilar Collective Intelligence Systems met November 12, 2013, to discuss issues involved in designing this consortium and to explore next steps. The task force concluded that a managed care biosimilars research consortium would be of significant value. Task force members agreed that it is best to use a distributed research network structurally similar to existing DARTNet, HMO Research Network, and Mini-Sentinel consortia. However, for some surveillance projects that it undertakes, the task force recognizes it may need supplemental data from managed care and other sources (i.e., a "hybrid" structure model). The task force believes that AMCP is well positioned to lead the biosimilar-monitoring effort and that the next step to developing a biosimilar-innovator collective intelligence system is to convene an advisory council to address organizational governance.

  5. Optimization of palm oil extraction from Decanter cake of small crude palm oil mill by aqueous surfactant solution using RSM

    Science.gov (United States)

    Ahmadi Pirshahid, Shewa; Arirob, Wallop; Punsuvon, Vittaya

    2018-04-01

    The use of hexane to extract vegetable oil from oilseeds or seed cake is of growing concern due to its environmental impact such as its smelling and toxicity. In our method, used Response Surface Methodology (RSM) was applied to study the optimum condition of decanter cake obtained from small crude palm oil with aqueous surfactant solution. For the first time, we provide an optimum condition of preliminary study with decanter cake extraction to obtain the maximum of oil yield. The result from preliminary was further used in RSM study by using Central Composite Design (CCD) that consisted of thirty experiments. The effect of four independent variables: the concentration of Sodium Dodecyl Sulfate (SDS) as surfactant, temperature, the ratio by weight to volume of cake to surfactant solution and the amount of sodium chloride (NaCl) on dependent variables are studied. Data were analyzed using Design-Expert 8 software. The results showed that the optimum condition of decanter cake extraction were 0.016M of SDS solution concentration, 73°C of extraction temperature, 1:10 (g:ml) of the ratio of decanter cake to SDS solution and 2% (w/w) of NaCl amount. This condition gave 77.05% (w/w) oil yield. The chemical properties of the extracted palm oil from this aqueous surfactant extraction are further investigated compared with the hexane extraction. The obtained result showed that all properties of both extractions were nearly the same.

  6. Road Safety Data, Collection, Transfer and Analysis DaCoTa. Workpackage 6, Driver Behaviour Monitoring through Naturalistic Driving: Deliverable 6.5: Naturalistic Driving for cross-national monitoring of SPIs and Exposure : an overview.

    NARCIS (Netherlands)

    Wegman, R.W.N. & Bos, N.M.

    2015-01-01

    WP6 of DaCoTA, Driver Behaviour Monitoring through Naturalistic Driving, focuses on the usefulness and feasibility of applying the Naturalistic Driving method for monitoring within the framework of ERSO. The aim is to continuously collect comparable information about the road safety level in EU

  7. Crude versus case-mix-adjusted control charts for safety monitoring in thyroid surgery.

    Science.gov (United States)

    Duclos, Antoine; Voirin, Nicolas; Touzet, Sandrine; Soardo, Pietro; Schott, Anne-Marie; Colin, Cyrille; Peix, Jean-Louis; Lifante, Jean-Christophe

    2010-12-01

    Patient-safety monitoring based on health-outcome indicators can lead to misinterpretation of changes in case mix. This study aimed to compare the detection of indicator variations between crude and case-mix-adjusted control charts using data from thyroid surgeries. The study population included each patient who underwent thyroid surgery in a teaching hospital from January 2006 to May 2008. Patient safety was monitored according to two indicators, which are immediately recognisable postoperative complications: recurrent laryngeal nerve palsy and hypocalcaemia. Each indicator was plotted monthly on a p-control chart using exact limits. The weighted κ statistic was calculated to measure the agreement between crude and case-mix-adjusted control charts. We evaluated the outcomes of 1405 thyroidectomies. The overall proportions of immediate recurrent laryngeal nerve palsy and hypocalcaemia were 7.4% and 20.5%, respectively. The proportion of agreement in the detection of indicator variations between the crude and case-mix-adjusted p-charts was 95% (95% CI 85% to 99%). The strength of the agreement was κ = 0.76 (95% CI 0.54 to 0.98). The single special cause of variation that occurred was only detected by the case-mix-adjusted p-chart. There was good agreement in the detection of indicator variations between crude and case-mix-adjusted p-charts. The joint use of crude and adjusted charts seems to be a reasonable approach to increase the accuracy of interpretation of variations in outcome indicators.

  8. Microcalorimetric study of the growth of Streptococcus thermophilus in renneted milk

    Directory of Open Access Journals (Sweden)

    Irina eStulova

    2015-02-01

    Full Text Available The growth of Streptococcus thermophilus ST12 (ST12 in liquid milk, reconstituted from low-heat skim milk powder (RSM and in RSM with rennet addition (r-RSM at 40°C was monitored by microcalorimetry. It was shown that the growth rate of bacteria decreased in renneted samples in comparison with liquid RSM starting from certain sizes of the colonies (deviation moments, which depended on the inoculation rates. The hydrolysis of lactose was delayed for about 1 h in the r-RSM in comparison with RSM but otherwise the metabolism of carbohydrates in the renneted and non-renneted milks was similar. The total free amino acids content by the end of fermentations was higher in r-RSM than in RSM presumably due to the enzymatic hydrolytic activity of rennet. The quantitatively dominating amino acids were remarkably different in the r-RSM and RSM indicating that the hydrolysis cascade of caseins and/or metabolism of amino acids by the bacteria functioned differently in the two cases. The data obtained showed potential of microcalorimetry to characterize quantitative differences of growth and metabolism of the bacteria in renneted and liquid samples of milk.

  9. Cu2+ Montmorillonite K10 Clay Catalyst as a Green Catalyst for Production of Stearic Acid Methyl Ester: Optimization Using Response Surface Methodology (RSM

    Directory of Open Access Journals (Sweden)

    Enas A. Almadani

    2018-01-01

    Full Text Available Clay catalyst has received much attention to replace the homogeneous catalysts in the esterification reaction to produce fatty acid methyl ester as the source of biodiesel as it is low cost, easily available, as well as environmental friendly. However, the use of unmodified clay, in particular montmorillonite K10 (MMT K10, for the esterification of fatty acids showed that the acid conversion was less than 60% and this is not preferable to the production of biodiesel. In this study, synthesis of stearic acid methyl ester using Cu2+-MMT K10 (Cu-MMT K10 was successfully optimized via response surface methodo-logy (RSM based on 3-variable of Box-Behnken design (BB. The parameters were; reaction time (5-180 minutes, reaction temperature (80-120 oC and concentration of Cu2+ in MMT K10 (0.25-1 M. The use of RSM in optimizing the conversion of stearic acid was successfully developed as the actual experimental conversion of stearic acid was found similar to the actual values under the optimum conditions. The model equation predicted that the following conditions would generate the maximum conversion of stearic acid (87.05 %reaction time of 62 minutes, a reaction temperature of 80 oC and catalyst used is 1.0 M Cu-MMT K10. This finding can be considered as green catalytic process as it worked at moderate reaction temperature using low cost clay catalyst with a short reaction time. Copyright © 2018 BCREC Group. All rights reserved Received: 26th July 2017; Revised: 13rd January 2018; Accepted: 13rd January 2018; Available online: 22nd January 2018; Published regularly: 2nd April 2018 How to Cite: Almadani, E.A., Harun, F.W., Radzi, S.M., Muhamad, S.K. (2018. Cu2+ Montmorillonite K10 Clay Catalyst as a Green Catalyst for Production of Stearic Acid Methyl Ester: Optimization Using Response Surface Methodology (RSM. Bulletin of Chemical Reaction Engineering & Catalysis, 13 (1: 187-195 (doi:10.9767/bcrec.13.1.1397.187-195

  10. Undersafe: Monitoring safety parameters in touristic mines and caves

    Science.gov (United States)

    Parcerisa, David; Sanmiquel, Lluís; Alfonso, Pura; Oliva, Josep

    2014-05-01

    Tourism is a key sector of the European economy, generating more than 5% of the EU GPD (Gross Domestic Product). Usually, underground touristic sites receive non-expert visitors; nevertheless these activities are poorly regulated or completely deregulated. Nowadays, safety is provided by underground expert professionals whom proceed to regular inspections and by basic safety infrastructures. Even with these measures, some potential personal and environmental dangers are always present and cannot be totally avoided. Therefore, there is a clear need of a new technological product for safety and environmental continuous monitoring of tourist underground attractions. So, the aim of the Undersafe project is to provide underground attractions with a novel and specifically tailored monitoring system, easy to use and maintain. One of the goals of the Undersafe project is to develop a rock falling detection based on a set of cost limited vibration sensors. Based on the technical needs, but with cost constraints, different types of potential sensors are considered: Underground microphone: It is placed in the surface or in the underground. It is based on the consideration that the impact of the stone generates a ground impact vibration which can be understood as a "noise" that is received by a microphone capsule. Airborne sound sensing microphone: It similarly applies to underground use of the microphones, but now the microphone is tested as for its traditional use (I.e. air sound detection). In such case, the microphone detects the environmental noise produced by the impact of the stone falling onto the ground, which will include the impact sound of the stone. Geophone: It is the de facto standard for ground vibrations. Although this technology was initially discarded due to its high cost, recently, low cost geophones have appeared in the market that allows its use inside the underground attractions. Accelerometers: These, can have enough sensibility to act as vibration

  11. A study on a reliability assessment methodology for the VHTR safety systems

    International Nuclear Information System (INIS)

    Lee, Hyung Sok

    2012-02-01

    The passive safety system of a 300MWt VHTR (Very High Temperature Reactor)which has attracted worldwide attention recently is actively considered for designing the improvement in the safety of the next generation nuclear power plant. The passive system functionality does not rely on an external source of the electrical support system,but on an intelligent use of the natural phenomena, such as convection, conduction, radiation, and gravity. It is not easy to evaluate quantitatively the reliability of the passive safety for the risk analysis considering the existing active system failure since the classical reliability assessment method could not be applicable. Therefore a new reliability methodology needs to be developed and applied for evaluating the reliability of the conceptual designed VHTR in this study. The preliminary evaluation and conceptualization are performed using the concept of the load and capacity theory related to the reliability physics model. The method of response surface method (RSM) is also utilized for evaluating the maximum temperature of nuclear fuel in this study. The significant variables and their correlation are considered for utilizing the GAMMA+ code. The proposed method might contribute to designing the new passive system of the VHTR

  12. Radiological safety system based on real-time tritium-in-air monitoring indoor and in effluents

    International Nuclear Information System (INIS)

    Bidica, Nicolae; Sofalca, Nicolae; Balteanu, Ovidiu-Ioan; Stefan, Ioana-Iuliana

    2007-01-01

    In this paper we describe an improved real-time tritium monitoring system designed for Heavy Water Detritiation Pilot Plant of National Institute for Cryogenics and Isotopes Separation, Rm. Valcea, Romania. The system consists of three fixed tritium-in-air monitors which measure continuously tritium-in-air concentration (in both species: vapour and gas) in working areas and gaseous effluents. Portable tritium monitors with ionization chamber, and tritium-in-air collector combined with liquid scintillation counter method are also used to supplement fixed instrument measurements. The main functions of tritium monitoring system are: to measure tritium-in air concentration in working areas and gaseous effluents; to alarm the personnel if tritium concentration thresholds are exceeded; to integrate tritium activity released to the environment during a week and to cut off normal ventilation when the activity threshold is exceeded and start the air cleaning system. Now, several especial functions have been added, so that by using appropriate conversion factors, the tritium monitoring system is able to estimate the effective dose rate before starting an activity into the monitored area, during this activity, or soon as the activity was finished. Another new function has been added by coupling tritium-in-air monitoring system with control access system. This is very useful for quick estimation of tritium doses. For routine dosimetric survey, one the internal dose for individuals by measuring tritium in urine is estimated. With all these features our tritium monitoring system is really a safety system for personnel and for environment. (authors)

  13. Flu Vaccine Safety Information

    Science.gov (United States)

    ... Influenza Types Seasonal Avian Swine Variant Pandemic Other Flu Vaccine Safety Information Questions & Answers Language: English (US) ... safety of flu vaccines monitored? Egg Allergy Are flu vaccines safe? Flu vaccines have good safety record. ...

  14. A reliability assessment methodology for the VHTR passive safety system

    International Nuclear Information System (INIS)

    Lee, Hyungsuk; Jae, Moosung

    2014-01-01

    The passive safety system of a VHTR (Very High Temperature Reactor), which has recently attracted worldwide attention, is currently being considered for the design of safety improvements for the next generation of nuclear power plants in Korea. The functionality of the passive system does not rely on an external source of an electrical support system, but on the intelligent use of natural phenomena. Its function involves an ultimate heat sink for a passive secondary auxiliary cooling system, especially during a station blackout such as the case of the Fukushima Daiichi reactor accidents. However, it is not easy to quantitatively evaluate the reliability of passive safety for the purpose of risk analysis, considering the existing active system failure since the classical reliability assessment method cannot be applied. Therefore, we present a new methodology to quantify the reliability based on reliability physics models. This evaluation framework is then applied to of the conceptually designed VHTR in Korea. The Response Surface Method (RSM) is also utilized for evaluating the uncertainty of the maximum temperature of nuclear fuel. The proposed method could contribute to evaluating accident sequence frequency and designing new innovative nuclear systems, such as the reactor cavity cooling system (RCCS) in VHTR to be designed and constructed in Korea.

  15. Examining Mechanical Strength Characteristics of Selective Inhibition Sintered HDPE Specimens Using RSM and Desirability Approach

    Science.gov (United States)

    Rajamani, D.; Esakki, Balasubramanian

    2017-09-01

    Selective inhibition sintering (SIS) is a powder based additive manufacturing (AM) technique to produce functional parts with an inexpensive system compared with other AM processes. Mechanical properties of SIS fabricated parts are of high dependence on various process parameters importantly layer thickness, heat energy, heater feedrate, and printer feedrate. In this paper, examining the influence of these process parameters on evaluating mechanical properties such as tensile and flexural strength using Response Surface Methodology (RSM) is carried out. The test specimens are fabricated using high density polyethylene (HDPE) and mathematical models are developed to correlate the control factors to the respective experimental design response. Further, optimal SIS process parameters are determined using desirability approach to enhance the mechanical properties of HDPE specimens. Optimization studies reveal that, combination of high heat energy, low layer thickness, medium heater feedrate and printer feedrate yielded superior mechanical strength characteristics.

  16. Application of electrochemical peroxidation (ECP) process for waste-activated sludge stabilization and system optimization using response surface methodology (RSM).

    Science.gov (United States)

    Gholikandi, Gagik Badalians; Kazemirad, Khashayar

    2018-03-01

    In this study, the performance of the electrochemical peroxidation (ECP) process for removing the volatile suspended solids (VSS) content of waste-activated sludge was evaluated. The Fe 2+ ions required by the process were obtained directly from iron electrodes in the system. The performance of the ECP process was investigated in various operational conditions employing a laboratory-scale pilot setup and optimized by response surface methodology (RSM). According to the results, the ECP process showed its best performance when the pH value, current density, H 2 O 2 concentration and the retention time were 3, 3.2 mA/cm 2 , 1,535 mg/L and 240 min, respectively. In these conditions, the introduced Fe 2+ concentration was approximately 500 (mg/L) and the VSS removal efficiency about 74%. Moreover, the results of the microbial characteristics of the raw and the stabilized sludge demonstrated that the ECP process is able to remove close to 99.9% of the coliforms in the raw sludge during the stabilization process. The energy consumption evaluation showed that the required energy of the ECP reactor (about 1.8-2.5 kWh (kg VSS removed) -1 ) is considerably lower than for aerobic digestion, the conventional waste-activated sludge stabilization method (about 2-3 kWh (kg VSS removed) -1 ). The RSM optimization process showed that the best operational conditions of the ECP process comply with the experimental results, and the actual and the predicted results are in good conformity with each other. This feature makes it possible to predict the introduced Fe 2+ concentrations into the system and the VSS removal efficiency of the process precisely.

  17. The EOP Visualization Module Integrated into the Plasma On-Line Nuclear Power Plant Safety Monitoring and Assessment System

    International Nuclear Information System (INIS)

    Hornaes, Arne; Hulsund, John Einar; Vegh, Janos; Major, Csaba; Horvath, Csaba; Lipcsei, Sandor; Kapocs, Gyoergy

    2001-01-01

    An ambitious project to replace the unit information systems (UISs) at the Hungarian Paks nuclear power plant was started in 1998-99. The basic aim of the reconstruction project is to install a modern, distributed UIS architecture on all four Paks VVER-440 units. The new UIS includes an on-line plant safety monitoring and assessment system (PLASMA), which contains a critical safety functions monitoring module and provides extensive operator support during the execution of the new, symptom-oriented emergency operating procedures (EOPs). PLASMA includes a comprehensive EOP visualization module, based on the COPMA-III procedure-handling software developed by the Organization for Economic Cooperation and Development, Halden Reactor Project. Intranet technology is applied for the presentation of the EOPs with the use of a standard hypertext markup language (HTML) browser as a visualization tool. The basic design characteristics of the system, with a detailed description of its user interface and functions of the new EOP display module, are presented

  18. Industrial safety and applied health physics. Annual report for 1977

    International Nuclear Information System (INIS)

    Auxier, J.A.; Davis, D.M.

    1978-06-01

    Progress is reported on the following: radiation monitoring with regard to personnel monitoring and health physics instrumentation; environs surveillance with regard to atmospheric monitoring, water monitoring, radiation background measurements, and soil and grass samples; radiation and safety surveys with regard to laboratory operations monitoring, radiation incidents, and laundry monitoring; industrial safety and special projects with regard to accident analysis, disabling injuries, and safety awards

  19. Safety logic systems of PFBR

    International Nuclear Information System (INIS)

    Sambasivan, S. Ilango

    2004-01-01

    Full text : PFBR is provided with two independent, fast acting and diverse shutdown systems to detect any abnormalities and to initiate safety action. Each system consists of sensors, signal processing systems, logics, drive mechanisms and absorber rods. The absorber rods of the first system are Control and Safety Rods (CSR) and that of the second are called as Diverse Safety Rods (DSR). There are nine CSR and three DSR. While CSR are used for startup, control of reactor power, controlled shutdown and SCRAM, the DSR are used only for SCRAM. The respective drive mechanisms are called as CSRDM and DSRDM. Each of these two systems is capable of executing the shutdown satisfactorily with single failure criteria. Two independent safety logic systems based on diverse principles have been designed for the two shut down systems. The analog outputs of the sensors of Core Monitoring Systems comprising of reactor flux monitoring, core temperature monitoring, failed fuel detection and core flow monitoring systems are processed and converted into binary signals depending on their instantaneous values. Safety logic systems receive the binary signals from these core-monitoring systems and process them logically to protect the reactor against postulated initiating events. Neutronic and power to flow (P/Q) signals form the inputs to safety logic system-I and temperature signals are inputs to the safety logic system II. Failed fuel detection signals are processed by both the shut down systems. The two logic systems to actuate the safety rods are also based on two diverse designs and implemented with solid-state devices to meet all the requirements of safety systems. Safety logic system I that caters to neutronic and P/Q signals is designed around combinational logic and has an on-line test facility to detect struck at faults. The second logic system is based on dynamic logic and hence is inherently safe. This paper gives an overview of the two logic systems that have been

  20. Employing response surface methodology (RSM) to improve methane production from cotton stalk.

    Science.gov (United States)

    Zhang, Han; Khalid, Habiba; Li, Wanwu; He, Yanfeng; Liu, Guangqing; Chen, Chang

    2018-03-01

    China is the largest cotton producer with the cotton output accounting for 25% of the total world's cotton production. A large quantity of cotton stalk (CS) waste is generated which is burned and causes environmental and ecological problems. This study investigated the anaerobic digestibility of CS by focusing on improving the methane yield by applying central composite design of response surface methodology (RSM). The purpose of this study was to determine the best level of factors to optimize the desired output of methane production from CS. Thus, it was necessary to describe the relationship of many individual variables with one or more response values for the effective utilization of CS. The influences of feed to inoculum (F/I) ratio and organic loading (OL) on methane production were investigated. Results showed that the experimental methane yield (EMY) and volatile solid (VS) removal were calculated to be 70.22 mL/gVS and 14.33% at F/I ratio of 0.79 and organic loading of 25.61 gVS/L, respectively. Characteristics of final effluent showed that the anaerobic system was stable. This research laid a foundation for future application of CS to alleviate the problems of waste pollution and energy output.

  1. Coagulation of landfill leachate by FeCl3: process optimization using Box-Behnken design (RSM)

    Science.gov (United States)

    Kumar, Smita S.; Bishnoi, Narsi R.

    2017-07-01

    FeCl3 coagulation was used to achieve maximum reduction of COD, phosphate, sulfate and color and process optimization (FeCl3 dosage, pH, reaction time) was done by BBD-RSM. Responses were recorded in terms of EC, COD, phosphate, color and sulfate removal. Variables A (pH) and B (reaction time) were negatively related to removal of COD and phosphate, whereas, C (FeCl3 dosage) was positive in case of COD removal and negative for phosphate removal. pH and coagulant dosage had negative relationship with color removal; however, reaction time showed positive relationship. In case of percent sulfate removal, variable A (pH) demonstrated negative relationship whereas B (reaction time) and C (FeCl3 dosage) were found to be positively related. Numerical optimization of the model revealed a maximum reduction of 71, 93, 86 and 99.6 % COD, phosphate, color and sulfate at optimal FeCl3 dosage = 3 g/l, pH 8, and reaction time = 95 min.

  2. Assessment of Pb (II Removal from Aqueous Solutions by Ascorbic Acid-stabilized Zero-valent Iron Nanoparticles Using Response Surface Methodology (RSM

    Directory of Open Access Journals (Sweden)

    Mohaddeseh Savasari

    2017-07-01

    Full Text Available The growing pollution of water resources and the limited availability of water supplies have led to a growing interest by researchers to develop novel methods of water remediation and reuse. One such method is the use of ascorbic acid-stabilized zero-valent iron nanoparticles (AAS-ZVIN for the removal of lead (Pb from aqueous solutions. Using zero-valent iron nanoparticles stabilized with acid ascorbic under aerobic conditions, the present study was conducted to assess the efficiency of Pb removal from aqueous solutions and its optimization by the response surface methodology (RSM. For this purpose, use was made of the central composite design and the response surface methodology with the four input variables of ASS- ZVIN dose (0.5, 1, and 2 g L-1, pH (2, 5, and 7, contact time (5, 20, and 60 min, and initial Pb concentration (5, 10, and 20 mg L-1 to determine the optimal conditions for the process. Numerical optimization revealed that the optimum conditions for Pb removal (97.93% included an ASS-ZVIN dose of 2 g L-1, an initial Pb (II concentration of 25 mg L-1, a contact time of 60 min, and an initial solution pH of 7. The results also imply that not only does ASS-ZVIN offer a good potential for the remediation of water bodies contaminated with Pb, given its high reactivity for Pb removal, but that  the RSM optimization process can be successfully employed for the optimization of the process in question.

  3. The development of condition monitoring for the safety of rotating machine in PWR using motor current signature analysis

    International Nuclear Information System (INIS)

    Syaiful Bakhri

    2013-01-01

    Condition monitoring of rotating machine is essential to guarantee the safety operation as well as to improve the efficiency of nuclear power plants operations. One of the promising condition monitoring techniques which has been preferred currently since it is simple, non-invasive and inexpensive is Motor Stator Signature Analysis (MCSA). However, the investigation of the MCSA technique using a compact, low cost, and having industrial class hardware which is capable for nuclear power plant applications has been limited. The research is aimed to develop condition monitoring method based on MCSA utilizing a compact industrial class for nuclear power plant. The investigation includes development of condition monitoring based on real-time FPGA-CompatRIO hardware, development of a custom built display module for early warning system, testing of the monitoring hardware, fault frequency analysis of electric motors including the performances of fault detections. The condition monitoring system is able to execute a fault detection task around 164 ms, to recognize accurately fault frequencies of stator shorted turn for about 75%, broken rotor bar around 95%, eccentricity 65%, mechanical misalignment 85%, including supply voltage unbalances 100%. The condition monitoring system based on its performance assessments could become a suitable alternative not only for rotating machines but also condition monitoring for other nuclear reactor components. (author)

  4. Design and implementation of an online risk monitor

    International Nuclear Information System (INIS)

    Majdara, A.; Nematollah, M. R.; Haddad, K.; Sepanloo, K.

    2006-01-01

    Probabilistic Safety Assessment is a powerful method for evaluating the safety of nuclear facilities. Probabilistic Safety Assessment models are the basis of online risk monitors, which can be utilized for monitoring the online risk. In this paper a newly developed risk monitor called Safety Assessment Tool is presented, and its main features and capabilities are introduced. Some of these features are: graphical event/fault tree developing interface, a 30-day risk profile, performing importance analysis, different administrative levels, and handling time dependent failure data. Safety Assessment Tool can be utilized in nuclear power plants, research reactors, etc. as an online assistant to manage safety issues and prevent high-risk configurations

  5. Developing Digital Image Techniques with Low-Cost Unmanned Mobile to Monitor the Safety of Dam and Affiliated Structure

    Science.gov (United States)

    Sung, Wen-Pei; Shih, Ming-Hsiang

    2016-04-01

    Global warming phenomena are increasingly serious, the El Niño and La Niña continue to occur repeatedly, causing the irregular drought and flood problem repeatedly. Mountain form of Taiwan is steep and storage ability of rainwater is insufficient to supply the livelihood of people and usage of industry which need to rely on rainwater reservoir. Thus, to ensure the water supply and self-reliance energy supply, one of ways to keep water resource is to build reservoir. Nevertheless, Taiwan is located on Pacific seismic belt; additionally, geological conditions are not fine, over-developed in the hills lead to more natural disasters in the future. Thus, strong shakes and typhoons which caused a degree of severe landslides around dam lead to reduce catchment of dam to result in affecting the safety of dam. Otherwise, the cracks and rusts in dam, induced by the defects of material, bad construction and seismic excitation respectively, thus, the mechanics phenomena of dam and its affiliated structures with crack are probing into the cause of stress concentration, induced high crack increase rate, affect the safety and usage of dam. This research is aimed at the safety evaluation technique of dam and its affiliated structures to develop three dimensional digital image correlation techniques for monitoring the safety of dam and its affiliated structures. Namely, developing the unmanned mobile on two axis of digital image correlation method is to detect the digital images from geometric scanning techniques for dam structure. This developed technique combined with Unmanned Aerial Vehicle (UAV) to develop the near filed scanning and monitoring techniques for local deformation and cracks on dam and its affiliated structures.

  6. A comparison RSM and ANN surface roughness models in thin-wall machining of Ti6Al4V using vegetable oils under MQL-condition

    Science.gov (United States)

    Mohruni, Amrifan Saladin; Yanis, Muhammad; Sharif, Safian; Yani, Irsyadi; Yuliwati, Erna; Ismail, Ahmad Fauzi; Shayfull, Zamree

    2017-09-01

    Thin-wall components as usually applied in the structural parts of aeronautical industry require significant challenges in machining. Unacceptable surface roughness can occur during machining of thin-wall. Titanium product such Ti6Al4V is mostly applied to get the appropriate surface texture in thin wall designed requirements. In this study, the comparison of the accuracy between Response Surface Methodology (RSM) and Artificial Neural Networks (ANN) in the prediction of surface roughness was conducted. Furthermore, the machining tests were carried out under Minimum Quantity Lubrication (MQL) using AlCrN-coated carbide tools. The use of Coconut oil as cutting fluids was also chosen in order to evaluate its performance when involved in end milling. This selection of cutting fluids is based on the better performance of oxidative stability than that of other vegetable based cutting fluids. The cutting speed, feed rate, radial and axial depth of cut were used as independent variables, while surface roughness is evaluated as the dependent variable or output. The results showed that the feed rate is the most significant factors in increasing the surface roughness value followed by the radial depth of cut and lastly the axial depth of cut. In contrary, the surface becomes smoother with increasing the cutting speed. From a comparison of both methods, the ANN model delivered a better accuracy than the RSM model.

  7. Tritium Room Air Monitor Operating Experience Review

    Energy Technology Data Exchange (ETDEWEB)

    L. C. Cadwallader; B. J. Denny

    2008-09-01

    Monitoring the breathing air in tritium facility rooms for airborne tritium is a radiological safety requirement and a best practice for personnel safety. Besides audible alarms for room evacuation, these monitors often send signals for process shutdown, ventilation isolation, and cleanup system actuation to mitigate releases and prevent tritium spread to the environment. Therefore, these monitors are important not only to personnel safety but also to public safety and environmental protection. This paper presents an operating experience review of tritium monitor performance on demand during small (1 mCi to 1 Ci) operational releases, and intentional airborne inroom tritium release tests. The tritium tests provide monitor operation data to allow calculation of a statistical estimate for the reliability of monitors annunciating in actual tritium gas airborne release situations. The data show a failure to operate rate of 3.5E-06/monitor-hr with an upper bound of 4.7E-06, a failure to alarm on demand rate of 1.4E-02/demand with an upper bound of 4.4E-02, and a spurious alarm rate of 0.1 to 0.2/monitor-yr.

  8. Tools for plant safety engineer

    International Nuclear Information System (INIS)

    Fabic, S.

    1996-01-01

    This paper contains: - review of tools for monitoring plant safety equipment reliability and readiness, before and accident (performance indicators for monitoring the risk and reliability performance and for determining when degraded performance alert levels are achieved) - brief reviews of tools for use during an accident: Emergency Operating Procedures (EOPs), Emergency Response Data System (ERDS), Reactor Safety Assessment System (RSAS), Computerized Accident Management Support

  9. Management of safety, safety culture and self assessment

    International Nuclear Information System (INIS)

    Carnino, A.

    2000-01-01

    Safety management is the term used for the measures required to ensure that an acceptable level of safety is maintained throughout the life of an installation, including decommissioning. The safety culture concept and its implementation are described in part one of the paper. The principles of safety are now quite well known and are implemented worldwide. It leads to a situation where harmonization is being achieved as indicated by the entry into force of the Convention on Nuclear Safety. To go beyond the present nuclear safety levels, management of safety and safety culture will be the means for achieving progress. Recent events which took place in major nuclear power countries have shown the importance of the management and the consequences on safety. At the same time, electricity deregulation is coming and will impact on safety through reductions in staffing and in operation and maintenance cost at nuclear installations. Management of safety as well as its control and monitoring by the safety authorities become a key to the future of nuclear energy.(author)

  10. Kinetic and isotherm analyses for thorium (IV) adsorptive removal from aqueous solutions by modified magnetite nanoparticle using response surface methodology (RSM)

    Energy Technology Data Exchange (ETDEWEB)

    Karimi, Mohammad, E-mail: m.karimi407@alumni.ut.ac.ir [School of Chemical Engineering, College of Engineering, University of Tehran, P.O. Box: 11365-4563, Tehran (Iran, Islamic Republic of); Milani, Saeid Alamdar [Nuclear Fuel Cycle Research School, Nuclear Science and Technology Research Institute, AEOI, P.O. Box: 14893-836, Tehran (Iran, Islamic Republic of); Abolgashemi, Hossein [School of Chemical Engineering, College of Engineering, University of Tehran, P.O. Box: 11365-4563, Tehran (Iran, Islamic Republic of)

    2016-10-15

    In this study, the ability and the adsorption capacity of magnetite/aminopropyltriethoxysilane/glutaraldehyde (Fe{sub 3}O{sub 4}/APTES/GA) adsorbent were evaluated for the adsorption of thorium (IV) ions from aqueous solutions. The influence of the several variables such as pH (1–5), Th (IV) initial concentration (50–300 mg L{sup −1}) and adsorbent concentration (1–5 g L{sup −1}) on the Th (IV) adsorption were investigated by response surface methodology (RSM). The results showed that the highest absorption capacity (q) was 107.23 mg g{sup −1} with respect to pH = 4.5, initial concentration of 250 mg L{sup −1} and adsorbent concentration of 1 g L{sup −1} for 90 min. Modeling equilibrium sorption data with the Langmuir, Freundlich and Dubinin–Radushkevich models pointed out that the results were in good agreement with Langmuir model. The experimental kinetic data were well fitted to pseudo-second-order equation with R{sup 2} = 0.9739. Also thermodynamic parameters (ΔG{sup o}, ΔH{sup o}, ΔS{sup o}) declared that the Th (IV) adsorption was endothermic and spontaneous. - Highlights: • Thorium ions were removed from aqueous solutions by modified magnetite nanoparticle. • The effects of process variables on adsorption capacity were investigated by RSM. • Thermodynamic parameters showed that the adsorption was endothermic and spontaneous. • The equilibrium data for the adsorption of Thorium followed the Langmuir isotherm. • The experimental kinetic data were described by the pseudo-second-order equation.

  11. Development of web monitoring radiation area monitor

    International Nuclear Information System (INIS)

    Jung, Hoon Jin; Lee, Jun Hee; Namkoong, Phil; Lee, Dong Hoon; Lee, Su Hong; Lee, Gun Bae

    2005-01-01

    Recently the increasing number of radioisotope industry and nuclear facility have ever raised the possibility of radiation safety accident. As such a result, radioisotope companies and nuclear facility operators have become to be much interested in radiation area monitoring for efficient radiation protection. At present, almost of the radiation area monitors which are imported products are outdated in aspect of their functions. Diversification of the monitoring work is urgently demanding additional functions to be added. Thus we have developed new-type digital area monitor which enables remote web monitoring with image and radiation dose rate value at distant places through using internet, the latest IT technology, and radiation measurement technology

  12. Use of remote monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Fournel, E; Gouilloux, C

    1977-01-01

    Paper traces the development of remote monitoring devices, since their first appearance for safety purposes. Discusses their uses in coal mines: working and safety (definitions); sources and channels of information (transmission of information by automatic or verbal means); mine control stations; duties and responsibilities of persons in charge. Examines the contribution made by remote monitoring to management in production sector. Gives examples of assistance given to production management showing a very advantageous result on balance, by their use. The use of computers in real time and in batched mode is compared. Discusses their use in monitoring mine atmosphere. Very favorable results have already been obtained in France and abroad. The broadening scope and future of remote monitoring is considered.

  13. Safety and Effectiveness of Highly Active Antiretroviral Therapy in Treatment-Naïve HIV Patients: Preliminary Findings of a Cohort Event Monitoring Study in Belarus.

    Science.gov (United States)

    Setkina, Svetlana; Dotsenko, Marina; Bondar, Sviatlana; Charnysh, Iryna; Kuchko, Alla; Kaznacheeva, Alena; Kozorez, Elena; Dodaleva, Alena; Rossa, Natalia

    2015-04-01

    Antiretroviral drugs have well-documented evidence-based favorable benefit-risk ratios. Although various studies have investigated and characterized the safety profile of antiretroviral medicines, there are a limited number of studies evaluating the safety of first-line antiretroviral therapy (ART) in patients with a specific co-morbidity. A cohort event monitoring (CEM) study of the safety and effectiveness of antiretroviral medicines in a target population that has a significant level of co-morbidities (chronic infectious diseases, peripheral blood cytopenias) was implemented. The aim was to evaluate the safety profile of the highly active ART (HAART) in the target population and subpopulations with risk factors, to optimize the monitoring and decision-making procedure for subgroups of patients with specific types of co-morbidity, and to implement a more vigilant approach to therapy management in risk groups of patients. Prospective observational CEM was implemented among HAART-naïve HIV-positive patients at four clinical sites from December 2012. Eligible patients were those starting first-line HAART. Close medical supervision of all enrolled patients, with regular clinical and laboratory monitoring, was provided by healthcare professionals within 1 year after commencement of therapy. Standardized forms were used for data collection on initial and subsequent visits. All objective or subjective deviations in condition (events) were assessed for a causal relationship with ART, and for severity, seriousness, reversibility, preventability, and pre-existing risk factors in the case of adverse drug reactions (ADRs). A total of 518 HAART-naïve HIV-positive patients were enrolled in the CEM study. Of these patients, 65% (337) experienced one or several ADRs related to one or more components of HAART. Most of the ADRs reported were non-serious, expected, common (very common), transient (correctable), or reversible. The most common were hematotoxic, hepatotoxic, and

  14. Amoxicillin degradation from contaminated water by solar photocatalysis using response surface methodology (RSM).

    Science.gov (United States)

    Moosavi, Fatemeh Sadat; Tavakoli, Touraj

    2016-11-01

    In this study, the solar photocatalytic process in a pilot plant with compound parabolic collectors (CPCs) was performed for amoxicillin (AMX) degradation, an antibiotic widely used in the world. The response surface methodology (RSM) based on Box-Behnken statistical experiment design was used to optimize independent variables, namely TiO 2 dosage, antibiotic initial concentration, and initial pH. The results showed that AMX degradation efficiency affected by positive or negative effect of variables and their interactions. The TiO 2 dosage, pH, and interaction between AMX initial concentration and TiO 2 dosage exhibited a synergistic effect, while the linear and quadratic term of AMX initial concentration and pH showed antagonistic effect in the process response. Response surface and contour plots were used to perform process optimization. The optimum conditions found in this regard were TiO 2 dosage = 1.5 g/L, AMX initial concentration = 17 mg/L, and pH = 9.5 for AMX degradation under 240 min solar irradiation. The photocatalytic degradation of AMX after 34.95 kJ UV /L accumulated UV energy per liter of solution was 84.12 % at the solar plant.

  15. Regression Modeling of EDM Process for AISI D2 Tool Steel with RSM

    Directory of Open Access Journals (Sweden)

    Shakir M. Mousa

    2018-01-01

    Full Text Available In this paper, Response Surface Method (RSM is utilized to carry out an investigation of the impact of input parameters: electrode type (E.T. [Gr, Cu and CuW], pulse duration of current (Ip, pulse duration on time (Ton, and pulse duration off time (Toff on the surface finish in EDM operation. To approximate and concentrate the suggested second- order regression model is generally accepted for Surface Roughness Ra, a Central Composite Design (CCD is utilized for evaluating the model constant coefficients of the input parameters on Surface Roughness (Ra. Examinations were performed on AISI D2 tool steel. The important coefficients are gotten by achieving successfully an Analysis of Variance (ANOVA at the 5 % confidence interval. The outcomes discover that Surface Roughness (Ra is much more impacted by E.T., Ton, Toff, Ip and little of their interactions action or influence. To predict the average Surface Roughness (Ra, a mathematical regression model was developed. Furthermore, for saving in time, the created model could be utilized for the choice of the high levels in the EDM procedure. The model adequacy was extremely agreeable as the constant Coefficient of Determination (R2 is observed to be 99.72% and adjusted R2-measurement (R2adj 99.60%.

  16. 10 CFR 34.47 - Personnel monitoring.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Personnel monitoring. 34.47 Section 34.47 Energy NUCLEAR REGULATORY COMMISSION LICENSES FOR INDUSTRIAL RADIOGRAPHY AND RADIATION SAFETY REQUIREMENTS FOR INDUSTRIAL RADIOGRAPHIC OPERATIONS Radiation Safety Requirements § 34.47 Personnel monitoring. (a) The licensee may not...

  17. Radiation Safety in Industrial Radiography. Specific Safety Guide (French Edition); Surete radiologique en radiographie industrielle

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-05-15

    This Safety Guide provides recommendations for ensuring radiation safety in industrial radiography used in non-destructive testing. This includes industrial radiography work that utilizes X ray and gamma sources, both in Horizontal-Ellipsis shielded facilities that have effective engineering controls and in outside shielded facilities using mobile sources. Contents: 1. Introduction; 2. Duties and responsibilities; 3. Safety assessment; 4. Radiation protection programme; 5. Training and qualification; 6. Individual monitoring of workers; 7. Workplace monitoring; 8. Control of radioactive sources; 9. Safety of industrial radiography sources and exposure devices; 10. Radiography in shielded enclosures; 11. Site radiography; 12. Transport of radioactive sources; 13. Emergency preparedness and response; Appendix: IAEA categorization of radioactive sources; Annex I: Example safety assessment; Annex II: Overview of industrial radiography sources and equipment; Annex III: Examples of accidents in industrial radiography.

  18. Toward risk assessment 2.0: Safety supervisory control and model-based hazard monitoring for risk-informed safety interventions

    International Nuclear Information System (INIS)

    Favarò, Francesca M.; Saleh, Joseph H.

    2016-01-01

    Probabilistic Risk Assessment (PRA) is a staple in the engineering risk community, and it has become to some extent synonymous with the entire quantitative risk assessment undertaking. Limitations of PRA continue to occupy researchers, and workarounds are often proposed. After a brief review of this literature, we propose to address some of PRA's limitations by developing a novel framework and analytical tools for model-based system safety, or safety supervisory control, to guide safety interventions and support a dynamic approach to risk assessment and accident prevention. Our work shifts the emphasis from the pervading probabilistic mindset in risk assessment toward the notions of danger indices and hazard temporal contingency. The framework and tools here developed are grounded in Control Theory and make use of the state-space formalism in modeling dynamical systems. We show that the use of state variables enables the definition of metrics for accident escalation, termed hazard levels or danger indices, which measure the “proximity” of the system state to adverse events, and we illustrate the development of such indices. Monitoring of the hazard levels provides diagnostic information to support both on-line and off-line safety interventions. For example, we show how the application of the proposed tools to a rejected takeoff scenario provides new insight to support pilots’ go/no-go decisions. Furthermore, we augment the traditional state-space equations with a hazard equation and use the latter to estimate the times at which critical thresholds for the hazard level are (b)reached. This estimation process provides important prognostic information and produces a proxy for a time-to-accident metric or advance notice for an impending adverse event. The ability to estimate these two hazard coordinates, danger index and time-to-accident, offers many possibilities for informing system control strategies and improving accident prevention and risk mitigation

  19. OPTIMASI DENGAN ALGORITMA RSM-CCD PADA EVAPORATOR VAKUM WATERJET DENGAN PENGENDALI SUHU FUZZY PADA PEMBUATAN PERMEN SUSU (RSM-CCD Algorithm for Optimizing Waterjet Vacuum Evaporator Using Fuzzy Temperature Control in The Milk Candy Production

    Directory of Open Access Journals (Sweden)

    Yusuf Hendrawan

    2016-10-01

    Full Text Available Milk candy is a product which has to be produced under a high temperature to achieve the caramelization process. The use of vacuum system during a food processing is one of the alternatives to engineer the value of a material’s boiling point. The temperature control system and the mixing speed in machine that produce the milk candy were expected to be able to prevent the formation of off-flavour in the final product. A smart control system based on fuzzy logic was applied in the temperature control within the double jacket vacuum evaporator machine that needs stable temperature in the cooking process. The objective of this research is developing vacuum evaporator for milk candy production using fuzzy temperature control. The result in machine and system planning showed that the process of milk candy production was going on well. The parameter optimization of water content and ash content purposed to acquire the temperature point parameter and mixing speed in milk candy production. The optimization method was response surface methodology (RSM, by using the model of central composite design (CCD. The optimization resulted 90.18oC for the temperature parameter and 512 RPM for the mixing speed, with the prediction about 4.69% of water content and 1.57% of ash content. Keywords: Optimization, vacuum evaporator, fuzzy, milk candy, response surface methodology ABSTRAK Permen susu merupakan salah satu produk yang diolah dengan suhu tinggi untuk mencapai proses karamelisasi. Pengolahan pangan dengan sistem vakum merupakan salah satu alternatif untuk merekayasa nilai titik didih suatu bahan. Sistem pengendalian suhu serta kecepatan pengadukan pada mesin produksi permen susu diharapkan dapat mencegah terbentuknya partikel hitam (off-flavour pada produk akhir. Sistem kontrol cerdas logika fuzzy diaplikasikan dalam pengendalian suhu pada mesin evaporator vakum double jacket yang membutuhkan tingkat stabilitas suhu pemasakan permen susu. Tujuan dari

  20. Hybrid causal methodology and software platform for probabilistic risk assessment and safety monitoring of socio-technical systems

    Energy Technology Data Exchange (ETDEWEB)

    Groth, Katrina, E-mail: kgroth@umd.ed [Center for Risk and Reliability, 0151 Glenn L. Martin Hall, University of Maryland, College Park, MD 20742 (United States); Wang Chengdong; Mosleh, Ali [Center for Risk and Reliability, 0151 Glenn L. Martin Hall, University of Maryland, College Park, MD 20742 (United States)

    2010-12-15

    This paper introduces an integrated framework and software platform for probabilistic risk assessment (PRA) and safety monitoring of complex socio-technical systems. An overview of the three-layer hybrid causal logic (HCL) modeling approach and corresponding algorithms, implemented in the Trilith software platform, are provided. The HCL approach enhances typical PRA methods by quantitatively including the influence of soft causal factors introduced by human and organizational aspects of a system. The framework allows different modeling techniques to be used for different aspects of the socio-technical system. The HCL approach combines the power of traditional event sequence diagram (ESD)event tree (ET) and fault tree (FT) techniques for modeling deterministic causal paths, with the flexibility of Bayesian belief networks for modeling non-deterministic cause-effect relationships among system elements (suitable for modeling human and organizational influences). Trilith enables analysts to construct HCL models and perform quantitative risk assessment and management of complex systems. The risk management capabilities included are HCL-based risk importance measures, hazard identification and ranking, precursor analysis, safety indicator monitoring, and root cause analysis. This paper describes the capabilities of the Trilith platform and power of the HCL algorithm by use of example risk models for a type of aviation accident (aircraft taking off from the wrong runway).

  1. Hybrid causal methodology and software platform for probabilistic risk assessment and safety monitoring of socio-technical systems

    International Nuclear Information System (INIS)

    Groth, Katrina; Wang Chengdong; Mosleh, Ali

    2010-01-01

    This paper introduces an integrated framework and software platform for probabilistic risk assessment (PRA) and safety monitoring of complex socio-technical systems. An overview of the three-layer hybrid causal logic (HCL) modeling approach and corresponding algorithms, implemented in the Trilith software platform, are provided. The HCL approach enhances typical PRA methods by quantitatively including the influence of soft causal factors introduced by human and organizational aspects of a system. The framework allows different modeling techniques to be used for different aspects of the socio-technical system. The HCL approach combines the power of traditional event sequence diagram (ESD)event tree (ET) and fault tree (FT) techniques for modeling deterministic causal paths, with the flexibility of Bayesian belief networks for modeling non-deterministic cause-effect relationships among system elements (suitable for modeling human and organizational influences). Trilith enables analysts to construct HCL models and perform quantitative risk assessment and management of complex systems. The risk management capabilities included are HCL-based risk importance measures, hazard identification and ranking, precursor analysis, safety indicator monitoring, and root cause analysis. This paper describes the capabilities of the Trilith platform and power of the HCL algorithm by use of example risk models for a type of aviation accident (aircraft taking off from the wrong runway).

  2. Reliability data update using condition monitoring and prognostics in probabilistic safety assessment

    Directory of Open Access Journals (Sweden)

    Hyeonmin Kim

    2015-03-01

    Full Text Available Probabilistic safety assessment (PSA has had a significant role in quantitative decision-making by finding design and operational vulnerabilities and evaluating cost-benefit in improving such weak points. In particular, it has been widely used as the core methodology for risk-informed applications (RIAs. Even though the nature of PSA seeks realistic results, there are still “conservative” aspects. One of the sources for the conservatism is the assumptions of safety analysis and the estimation of failure frequency. Surveillance, diagnosis, and prognosis (SDP, utilizing massive databases and information technology, is worth highlighting in terms of its capability for alleviating the conservatism in conventional PSA. This article provides enabling techniques to solidify a method to provide time- and condition-dependent risks by integrating a conventional PSA model with condition monitoring and prognostics techniques. We will discuss how to integrate the results with frequency of initiating events (IEs and probability of basic events (BEs. Two illustrative examples will be introduced: (1 how the failure probability of a passive system can be evaluated under different plant conditions and (2 how the IE frequency for a steam generator tube rupture (SGTR can be updated in terms of operating time. We expect that the proposed model can take a role of annunciator to show the variation of core damage frequency (CDF depending on operational conditions.

  3. Reliability data update using condition monitoring and prognostics in probabilistic safety assessment

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyeon Min; Lee, Sang Hwan; Park, Jun Seok; Kim, Hyung Dae; Chang, Yoon Suk; Heo, Gyun Young [Dept. of Nuclear Engineering, Kyung Hee University, Yongin (Korea, Republic of)

    2015-03-15

    Probabilistic safety assessment (PSA) has had a significant role in quantitative decision making by finding design and operational vulnerabilities and evaluating cost-benefit in improving such weak points. In particular, it has been widely used as the core methodology for risk-informed applications (RIAs). Even though the nature of PSA seeks realistic results, there are still 'conservative' aspects. One of the sources for the conservatism is the assumptions of safety analysis and the estimation of failure frequency. Surveillance, diagnosis, and prognosis (SDP), utilizing massive databases and information technology, is worth highlighting in terms of its capability for alleviating the conservatism in conventional PSA. This article provides enabling techniques to solidify a method to provide time and condition-dependent risks by integrating a conventional PSA model with condition monitoring and prognostics techniques. We will discuss how to integrate the results with frequency of initiating events (IEs) and probability of basic events (BEs). Two illustrative examples will be introduced: (1) how the failure probability of a passive system can be evaluated under different plant conditions and (2) how the IE frequency for a steam generator tube rupture (SGTR) can be updated in terms of operating time. We expect that the proposed model can take a role of annunciator to show the variation of core damage frequency (CDF) depending on operational conditions.

  4. 10 CFR 39.65 - Personnel monitoring.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Personnel monitoring. 39.65 Section 39.65 Energy NUCLEAR REGULATORY COMMISSION LICENSES AND RADIATION SAFETY REQUIREMENTS FOR WELL LOGGING Radiation Safety Requirements § 39.65 Personnel monitoring. (a) The licensee may not permit an individual to act as a logging...

  5. Supervision of the safety culture in nuclear facilities

    International Nuclear Information System (INIS)

    2014-11-01

    This brochure issued by the Swiss Federal Nuclear Safety Inspectorate ENSI reports on safety culture aspects in nuclear facilities and ENSI’s activities as a supervisory instance. ENSI is the independent supervisory authority for the nuclear sector in Switzerland. A definition of safety culture is presented and the development of the concepts used in its monitoring are discussed. The main attributes of a good safety culture are discussed. Further, the conceptual basics and principles of such monitoring are looked at and the methods used for the supervision of safety culture in nuclear facilities are described

  6. A monitor for consumer confidence in the safety of food

    NARCIS (Netherlands)

    Jonge, de J.

    2008-01-01

    Despite the fact that in the developed countries food safety standards are higher than ever, food safety incidents continue to occur frequently. The accumulation of food safety incidents might affect general consumer confidence in the safety of food. Therefore, in this thesis, the concept of general

  7. Radiation Safety in Industrial Radiography. Specific Safety Guide (Spanish Edition); Seguridad radiologica en la radiografia industrial

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-12-15

    This Safety Guide provides recommendations for ensuring radiation safety in industrial radiography used in non-destructive testing. This includes industrial radiography work that utilizes X ray and gamma sources, both in shielded facilities that have effective engineering controls and in outside shielded facilities using mobile sources. Contents: 1. Introduction; 2. Duties and responsibilities; 3. Safety assessment; 4. Radiation protection programme; 5. Training and qualification; 6. Individual monitoring of workers; 7. Workplace monitoring; 8. Control of radioactive sources; 9. Safety of industrial radiography sources and exposure devices; 10. Radiography in shielded enclosures; 11. Site radiography; 12. Transport of radioactive sources; 13. Emergency preparedness and response; Appendix: IAEA categorization of radioactive sources; Annex I: Example safety assessment; Annex II: Overview of industrial radiography sources and equipment; Annex III: Examples of accidents in industrial radiography.

  8. 49 CFR 385.107 - The safety audit.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false The safety audit. 385.107 Section 385.107 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS SAFETY FITNESS PROCEDURES Safety Monitoring System for Mexico-Domicile...

  9. Safety in cardiac surgery

    NARCIS (Netherlands)

    Siregar, S.

    2013-01-01

    The monitoring of safety in cardiac surgery is a complex process, which involves many clinical, practical, methodological and statistical issues. The objective of this thesis was to measure and to compare safety in cardiac surgery in The Netherlands using the Netherlands Association for

  10. White paper on nuclear safety in 2009

    International Nuclear Information System (INIS)

    2009-06-01

    It deals with a general introduction of nuclear safety like general safety, safety regulation and system law and standard. It indicates of nuclear energy facility safety about general safety, safety regulation of operating nuclear power plant safety regulation under constructing nuclear power plant. It deals with radiation facility safety, monitoring of environmental radiation, radiation protection, radiation control, international cooperating on nuclear energy safety and establishment of safety regulation.

  11. Risk-based safety indicators

    International Nuclear Information System (INIS)

    Szikszai, T.

    1997-01-01

    The presentation discusses the following issues: The objectives of the risk-based indicator programme. The characteristics of the risk-based indicators. The objectives of risk-based safety indicators - in monitoring safety; in PSA applications. What indicators? How to produce the risk based indicators? PSA requirements

  12. Applied Health Physics and Safety annual report for 1975

    International Nuclear Information System (INIS)

    1976-08-01

    This report describes and summarizes the activities of the applied sections and/or groups of the Health Physics Division. Projects and activities covered include personnel monitoring, environmental monitoring, radiation and safety surveys, and industrial safety

  13. Safety performance indicators used by the Russian Safety Regulatory Authority in its practical activities on nuclear power plant safety regulation

    International Nuclear Information System (INIS)

    Khazanov, A.L.

    2005-01-01

    The Sixth Department of the Nuclear, Industrial and Environmental Regulatory Authority of Russia, Scientific and Engineering Centre for Nuclear and Radiation Safety process, analyse and use the information on nuclear power plants (NPPs) operational experience or NPPs safety improvement. Safety performance indicators (SPIs), derived from processing of information on operational violations and analysis of annual NPP Safety Reports, are used as tools to determination of trends towards changing of characteristics of operational safety, to assess the effectiveness of corrective measures, to monitor and evaluate the current operational safety level of NPPs, to regulate NPP safety. This report includes a list of the basic SPIs, those used by the Russian safety regulatory authority in regulatory activity. Some of them are absent in list of IAEA-TECDOC-1141 ('Operational safety performance indicators for nuclear power plants'). (author)

  14. Critical review of safety performance metrics

    NARCIS (Netherlands)

    Karanikas, Nektarios

    2016-01-01

    Various tools for safety performance measurement have been introduced in order to fulfil the need for safety monitoring in organisations, which is tightly related to their overall performance and achievement of their business goals. Such tools include accident rates, benchmarking, safety culture and

  15. Environmental and Occupational Safety Division annual progress report for 1983

    International Nuclear Information System (INIS)

    1984-11-01

    This report presents summaries of activities conducted during 1983 in the following areas: radiation monitoring; health physics instrumentation development; environmental management; atmospheric monitoring; water monitoring; background radiation measurements; soil and grass samples; deer samples; calculation of potential radiation dose to the public; industrial safety; and operational safety

  16. Development of a new methodology for quantifying nuclear safety culture

    International Nuclear Information System (INIS)

    Han, Kiyoon; Jae, Moosung

    2017-01-01

    The present study developed a Safety Culture Impact Assessment Model (SCIAM) which consists of a safety culture assessment methodology and a safety culture impact quantification methodology. The SCIAM uses a safety culture impact index (SCII) to monitor the status of safety culture of NPPs periodically and it uses relative core damage frequency (RCDF) to present the impact of safety culture on the safety of NPPs. As a result of applying the SCIAM to the reference plant (Kori 3), the standard for the healthy safety culture of the reference plant is suggested. SCIAM might contribute to improve the safety of NPPs (Nuclear Power Plants) by monitoring the status of safety culture periodically and presenting the standard of healthy safety culture.

  17. Development of a new methodology for quantifying nuclear safety culture

    Energy Technology Data Exchange (ETDEWEB)

    Han, Kiyoon; Jae, Moosung [Hanyang Univ., Seoul (Korea, Republic of). Dept. of Nuclear Engineering

    2017-01-15

    The present study developed a Safety Culture Impact Assessment Model (SCIAM) which consists of a safety culture assessment methodology and a safety culture impact quantification methodology. The SCIAM uses a safety culture impact index (SCII) to monitor the status of safety culture of NPPs periodically and it uses relative core damage frequency (RCDF) to present the impact of safety culture on the safety of NPPs. As a result of applying the SCIAM to the reference plant (Kori 3), the standard for the healthy safety culture of the reference plant is suggested. SCIAM might contribute to improve the safety of NPPs (Nuclear Power Plants) by monitoring the status of safety culture periodically and presenting the standard of healthy safety culture.

  18. Cell growth and proteolytic activity of Lactobacillus acidophilus, Lactobacillus helveticus, Lactobacillus delbrueckii ssp. bulgaricus, and Streptococcus thermophilus in milk as affected by supplementation with peptide fractions.

    Science.gov (United States)

    Gandhi, Akanksha; Shah, Nagendra P

    2014-12-01

    The present investigation examined the effects of supplementation of milk peptide fractions produced by enzymatic hydrolysis on the fermentation of reconstituted skim milk (RSM). Changes in pH, cell growth, proteolytic activity, and angiotensin-converting enzyme (ACE)-inhibitory activity were monitored during fermentation of RSM by pure cultures of Lactobacillus acidophilus, Lactobacillus helveticus, Lactobacillus delbrueckii ssp. bulgaricus, and Streptococcus thermophilus. The study showed that supplementation with peptide fractions of different molecular weights did not significantly affect the bacterial growth in RSM. All bacteria showed an increased proteolytic activity in RSM supplemented with large peptides (>10 kDa), and L. helveticus in general exhibited the highest proteolytic activity among the bacteria studied. The ACE-inhibitory activity was observed to be the maximum in RSM supplemented with larger peptides (>10 kDa) for all bacteria. The results suggest that proteolysis by bacteria leads to increased production of ACE-inhibitory peptides compared to the supplemented peptides produced by enzymatic hydrolysis.

  19. Use of the Safety probabilistic analysis for the risk monitor before maintenance

    International Nuclear Information System (INIS)

    Gonzalez C, M.

    2004-01-01

    In this work the use of the Safety Probabilistic Analysis (APS) of the Laguna Verde Power plant to quantify the risk before maintenance is presented. Beginning to describe the nature of the Rule of Maintenance and their risk evaluations, it is planned about the paper of the APS for that purpose, and a systematic form to establish the reaches for this use open of the model is delineated. The work provides some technique details of the implantation methods of the APS like risk monitor, including the form of introducing the systems, trains and components to the user, as well as the fitness to the models and improvements to the used platform. There are covered some of the measures taken to achieve the objectives of preserving the base model approved, to facilitate the periodic realize, and to achieve acceptable times of execution for their efficient use. (Author)

  20. Safety culture

    International Nuclear Information System (INIS)

    Drukraroff, C.

    2010-01-01

    The concept of Safety Culture was defined after Chernobyl's nuclear accident in 1986. It has not been exempt from discussion interpretations, adding riders, etc..., over the last 24 years because it has to do with human behavior and performance in the organizations. Safety Culture is not an easy task to define, assess and monitor. The proof of it is that today we still discussing and writing about it. How has been the evolution of Safety Culture at the Juzbado Factory since 1985 to today?. What is the strategy that we will be following in the future. (Author)

  1. Human Factors and Safety Culture in Maritime Safety (revised

    Directory of Open Access Journals (Sweden)

    Heinz Peter Berg

    2013-09-01

    Full Text Available As in every industry at risk, the human and organizational factors constitute the main stakes for maritime safety. Furthermore, several events at sea have been used to develop appropriate risk models. The investigation on maritime accidents is, nowadays, a very important tool to identify the problems related to human factor and can support accident prevention and the improvement of maritime safety. Part of this investigation should in future also be near misses. Operation of ships is full of regulations, instructions and guidelines also addressing human factors and safety culture to enhance safety. However, even though the roots of a safety culture have been established, there are still serious barriers to the breakthrough of the safety management. One of the most common deficiencies in the case of maritime transport is the respective monitoring and documentation usually lacking of adequacy and excellence. Nonetheless, the maritime area can be exemplified from other industries where activities are ongoing to foster and enhance safety culture.

  2. Safety parameter display system: an operator support system for enhancement of safety in Indian PHWRs

    International Nuclear Information System (INIS)

    Subramaniam, K.; Biswas, T.

    1994-01-01

    Ensuring operational safety in nuclear power plants is important as operator errors are observed to contribute significantly to the occurrence of accidents. Computerized operator support systems, which process and structure information, can help operators during both normal and transient conditions, and thereby enhance safety and aid effective response to emergency conditions. An important operator aid being developed and described in this paper, is the safety parameter display system (SPDS). The SPDS is an event-independent, symptom-based operator aid for safety monitoring. Knowledge-based systems can provide operators with an improved quality of information. An information processing model of a knowledge based operator support system (KBOSS) developed for emergency conditions using an expert system shell is also presented. The paper concludes with a discussion of the design issues involved in the use of a knowledge based systems for real time safety monitoring and fault diagnosis. (author). 8 refs., 4 figs., 1 tab

  3. Development and installation of a new on-line plant safety monitoring system for the Paks VVER-440 units

    International Nuclear Information System (INIS)

    Vegh, J.; Major, C.; Buerger, L.; Lipcsei, S.; Horvath, C.; Kapocs, G.; Eiler, J.; Hornaes, A.; Hulsund, J.E.

    2000-01-01

    The paper describes the architecture, modules, algorithms and human-machine interface of a new operator support system (OSS), which is integrated into the new, reconstructed Paks NPP plant computers. The main task of the new OSS is to perform continuous plant safety monitoring and assessment, it has the following basic functions: on-line evaluation and presentation of critical safety function (CSF) status trees, continuous evaluation and presentation of the actual safety status of the plant, displaying and browsing the new symptom-oriented EOPs, automatic displaying of those process signals which are quoted in the EOPs. The first version of the new operator support system was connected to the Paks NPP full scope simulator in October 1999. This configuration was later successfully applied for the simulator testing of the new symptom-oriented EOP set for the Paks NPP in November 1999. The installation process was continued in 2000: the new system started its operation on Unit 2 (June) and on Unit 1 (August), together with the reconstructed, new PCS. (author)

  4. Response surface methodology (RSM) based multi-objective optimization of fusel oil -gasoline blends at different water content in SI engine

    International Nuclear Information System (INIS)

    Awad, Omar I.; Mamat, R.; Ali, Obed M.; Azmi, W.H.; Kadirgama, K.; Yusri, I.M.; Leman, A.M.; Yusaf, T.

    2017-01-01

    Highlights: • The optimal ratio ratio of fusel oil–gasoline blended fuels is proposed. • The water content of fusel oil was reduced from 13.5% to 6.5%. • The heating value of fusel oil was improved by 13%. • FAWE 20 fuels were found to be optimal values with a high desirability of 0.707. • RSM was applied to optimize the engine performance and exhaust emissions. - Abstract: The main objective of this study is to determine the optimal blend ratio of fusel oil–gasoline before and after water extraction (FBWE10, FBWE20, FAWE10, and FAWE20) regarding the performance and emissions of spark ignition engine using response surface methodology (RSM). The multi-objective optimization is applied to maximize the brake power, brake thermal efficiency and minimize the brake specific fuel consumption (BSFC), NOx emission, HC emission and CO emission. The water content of fusel oil has been extracted by employing rotary extractor method. The experimental of this study has been carried out with different fusel oil–gasoline blends, different throttle valve opening position (15%, 30%, 45% and 60%) and different engine speed (1500, 2500, 3500 and 4500 rpm). All the developed models for responses were determined to be statistically significant at 95% confidence level. The study results reveal an improvement in heating value of fusel oil after water extraction with FAWE20 (80 vol% gasoline fuel, 20 vol% fusel oil after water extracted) as the optimally blended fuel. The best condition of engine parameters with FAWE20 were 55.4% of WOT for load and 4499 rpm engine speed. In additional of the optimal values with a high desirability of 0.707 were 62.511 kW, 241.139 g/kW h, 36%, 1895.913 ppm140.829 ppm and % for brake power, BSFC, BTE, NO x , HC and CO emissions respectively. The reduction of water content in fusel oil has a statistical significance influence to increases BTE, NO x emission and decreases the BSFC, HC and CO emissions.

  5. An assessment of uncertainty on a LOFT L2-5 LBLOCA PCT based on the ACE-RSM approach: complementary work for the OECD BEMUSE PHASE-III program

    International Nuclear Information System (INIS)

    Ahn, Kwang Il; Chung, Bub Dong; Lee, John C.

    2010-01-01

    As pointed out in the OECD BEMUSE Program, when a high computation time is taken to obtain the relevant output values of a complex physical model (or code), the number of statistical samples that must be evaluated through it is a critical factor for the sampling-based uncertainty analysis. Two alternative methods have been utilized to avoid the problem associated with the size of these statistical samples: one is based on Wilks' formula, which is based on simple random sampling, and the other is based on the conventional nonlinear regression approach. While both approaches provide a useful means for drawing conclusions on the resultant uncertainty with a limited number of code runs, there are also some unique corresponding limitations. For example, a conclusion based on the Wilks' formula can be highly affected by the sampled values themselves, while the conventional regression approach requires an a priori estimate on the functional forms of a regression model. The main objective of this paper is to assess the feasibility of the ACE-RSM approach as a complementary method to the Wilks' formula and the conventional regression-based uncertainty analysis. This feasibility was assessed through a practical application of the ACE-RSM approach to the LOFT L2-5 LBLOCA PCT uncertainty analysis, which was implemented as a part of the OECD BEMUSE Phase III program

  6. Monitoring for safety and reliability

    International Nuclear Information System (INIS)

    Garcia Peyrano, O.

    1994-01-01

    This paper is related to the development of a Condition Monitoring Center for the CNEA production plants. A pilot surveillance program is now in operation using the main pump of the RA-6 REACTOR, and small tests set up. Radio links, and digital data transmission systems is in operation in both cases. Standard software is used for data acquisition, function calculation and post processing. (author). 7 figs

  7. Management options for recycling radioactive scrap metals

    Energy Technology Data Exchange (ETDEWEB)

    Dehmel, J.C.; MacKinney, J.; Bartlett, J.

    1997-02-01

    The feasibility and advantages of recycling radioactive scrap metals (RSM) have yet to be assessed, given the unique technical, regulatory, safety, and cost-benefit issues that have already been raised by a concerned recycling industry. As is known, this industry has been repeatedly involved with the accidental recycling of radioactive sources and, in some cases, with costly consequences. If recycling were deemed to be a viable option, it might have to be implemented with regulatory monitoring and controls. Its implementation may have to consider various and complex issues and address the requirements and concerns of distinctly different industries. There are three basic options for the recycling of such scraps. They are: (1) recycling through the existing network of metal-scrap dealers and brokers, (2) recycling directly and only with specific steelmills, or (3) recycling through regional processing centers. Under the first option, scrap dealers and brokers would receive material from RSM generators and determine at which steelmills such scraps would be recycled. For the second option, RSM generators would deal directly with selected steelmills under specific agreements. For the third option, generators would ship scraps only to regional centers for processing and shipment to participating steelmills. This paper addresses the potential advantages of each option, identifies the types of arrangements that would need to be secured among all parties, and attempts to assess the receptivity of the recycling industry to each option.

  8. Programmes and Systems for Source and Environmental Radiation Monitoring

    International Nuclear Information System (INIS)

    2010-01-01

    The discharge of radionuclides to the atmosphere and aquatic environments is a legitimate practice in the nuclear and other industries, hospitals and research. Where appropriate, monitoring of the discharges and of relevant environmental media is an essential regulatory requirement in order to ensure appropriate radiation protection of the public. Such monitoring provides information on the actual amounts of radioactive material discharged and the radionuclide concentrations in the environment, and is needed to demonstrate compliance with authorized limits, to assess the radiation exposure of members of the public and to provide data to aid in the optimization of radiation protection. Uncontrolled releases of radionuclides to the atmosphere and aquatic environments may occur as a result of a nuclear or radiological accident. Again, monitoring at the source of the release and of the environment is necessary. In this case, monitoring is used both to assess the radiation exposure of members of the public and to determine the actions necessary for public protection, including longer term countermeasures. Source and environmental monitoring associated with the release of radionuclides to the environment is the subject of a number of IAEA Safety Standards, particularly IAEA Safety Standard RS-G-1.8 (Environmental and Source Monitoring for Purposes of Radiation Protection). This publication is intended to complement this Safety Guide and, by so doing, replaces Safety Series No. 41 (Objectives and Design of Environmental Monitoring Programmes for Radioactive Contaminants) and Safety Series No. 46 (Monitoring of Airborne and Liquid Radioactive Releases from Nuclear Facilities to the Environment). Like Safety Standard RS-G-1.8, this Safety Report deals with monitoring at the source and in the environment associated with authorized releases of radionuclides to the environment. It also deals with the general issues of emergency monitoring during and in the aftermath of an

  9. Health and safety at DNE [Dounreay Nuclear Power Development Establishment

    International Nuclear Information System (INIS)

    Walford, J.G.; Tyler, G.R.

    1988-11-01

    This report reviews health and safety experience at the UKAEA's Dounreay Nuclear Power Development Establishment for 1986 and gives relevant data in the fields of health physics and general safety. It includes sections on: organization, policy and training; monitoring of the working environment; personnel monitoring; protection of the public; radiological incidents; and non-radiological health and safety. (author)

  10. Monitoring of surface and airborne contamination

    Energy Technology Data Exchange (ETDEWEB)

    Pradeep Kumar, K S [Bhabha Atomic Research Centre, Bombay (India)

    1997-06-01

    Indian nuclear energy programme aims at total safety in all activities involved in the entire fuel cycle for the occupational workers, members of the public and the environment as a whole. Routine radiation monitoring with clearly laid out procedures are followed for ensuring the safety of workers and public. Radiation monitoring carried out for the nuclear installations comprises of process monitoring, monitoring of effluent releases and also of the radiation protection monitoring of the individuals, work place and environment. Regulations like banning of smoking and consumption of food and drink etc. reduces the risk of direct ingestion even if inadvertent spread of contamination takes place. Though limit of transportable surface contamination is prescribed, the health physicists always follow a ``clean on swipe`` philosophy which compensates any error in the measurement of surface contamination. In this paper, the following items are contained: Necessity of contamination monitoring, accuracy required in the calibration of surface contamination monitors, methodology for contamination monitoring, air monitoring, guidelines for unrestricted release of scrap materials, and problems in contamination monitoring. (G.K.)

  11. Safety-barrier diagrams as a tool for modelling safety of hydrogen applications

    DEFF Research Database (Denmark)

    Duijm, Nijs Jan; Markert, Frank

    2009-01-01

    Safety-barrier diagrams have proven to be a useful tool in documenting the safety measures taken to prevent incidents and accidents in process industry. Especially during the introduction of new hydrogen technologies or applications, as e.g. hydrogen refuelling stations, safety-barrier diagrams...... are considered a valuable supplement to other traditional risk analysis tools to support the communication with authorities and other stakeholders during the permitting process. Another advantage of safety-barrier diagrams is that they highlight the importance of functional and reliable safety barriers in any...... system and here is a direct focus on those barriers that need to be subject to safety management in terms of design and installation, operational use, inspection and monitoring, and maintenance. Safety-barrier diagrams support both quantitative and qualitative approaches. The paper will describe...

  12. “Be Careful Who You Friend:” Early Adolescents’ Reports of Safety, Privacy, and Family Monitoring of Facebook Use

    Directory of Open Access Journals (Sweden)

    Linda Charmaraman

    2014-03-01

    Full Text Available With the growing popularity of social networking sites (SNS, parents, educators, youth development workers, researchers, and policymakers are increasingly concerned with Internet safety issues. In this paper we highlight a study designed to understand how young people describe how much (or how little social network monitoring is happening in their home life, including who is doing the monitoring, when, why, and how. Participants included 33 middle school youth (aged 11-14 who were participating in a 9-week sexual health curriculum. Teens reported that their parents were most concerned about “friending” the wrong people and swearing on Facebook postings. In contrast, teens talked more about using Facebook to keep in touch with their known social circle and were not as preoccupied with adding people they didn’t know or wanting to meet strangers online. Teens also reported that female family and community members were the most frequent monitors of their Facebook pages. Implications for youth development programs and future research directions are discussed.

  13. Monitoring the anaesthetist in the operating theatre - professional competence and patient safety.

    Science.gov (United States)

    Larsson, J

    2017-01-01

    This article about competence and patient safety in anaesthesia was inspired by a statement in the 2015 AAGBI guidelines on monitoring during anaesthesia: 'the presence of an appropriately trained and experienced anaesthetist is important for patient safety during anaesthesia'. The review starts with a structured description of competence, presenting five dimensions of it; the first two dimensions are identical with the two classical attributes of competence, practical skills and theoretical knowledge. Concerning skills, the value of aiming for a high level of proficiency early in a traning programme is pointed out, and deliberate practice is given as an example of a pedagogical model where aiming for excellence is a core idea. For theoretical knowledge, the value of a deep approach to learning physiology and basic sciences is stressed. The third dimension (anaesthetists' non-technical skills), represents skills necessary for good team-work in the operating theatre. The two last dimensions of competence are the understanding of work and intuitive expert knowing. Understanding work means being aware of what the work is about, appreciating the different aspects of the anaesthetist's job. Intuitive expert knowing, lastly, concerns the tacit dimension of knowledge and skills, which enables professional experts to quickly find a working solution for most clinical problems. The final part of the review is about the 'when' and 'how' of competence assessment. The main message is the importance of assessing the competence of clinically active anaesthetists regularly during their whole career. © 2017 The Association of Anaesthetists of Great Britain and Ireland.

  14. Progress report: 1996 Radiation Safety Systems Division

    International Nuclear Information System (INIS)

    Bhagwat, A.M.; Sharma, D.N.; Abani, M.C.; Mehta, S.K.

    1997-01-01

    The activities of Radiation Safety Systems Division include (i) development of specialised monitoring systems and radiation safety information network, (ii) radiation hazards control at the nuclear fuel cycle facilities, the radioisotope programmes at Bhabha Atomic Research Centre (BARC) and for the accelerators programme at BARC and Centre for Advanced Technology (CAT), Indore. The systems on which development and upgradation work was carried out during the year included aerial gamma spectrometer, automated environment monitor using railway network, radioisotope package monitor and air monitors for tritium and alpha active aerosols. Other R and D efforts at the division included assessment of risk for radiation exposures and evaluation of ICRP 60 recommendations in the Indian context, shielding evaluation and dosimetry for the new upcoming accelerator facilities and solid state nuclear track detector techniques for neutron measurements. The expertise of the divisional members was provided for 36 safety committees of BARC and Atomic Energy Regulatory Board (AERB). Twenty three publications were brought out during the year 1996. (author)

  15. Applied health physics and safety annual report for 1976

    International Nuclear Information System (INIS)

    Auxier, J.A.; Davis, D.M.

    1977-08-01

    Progress is reported in the following areas of research: personnel monitoring; health physics instrumentation; atmospheric monitoring; water monitoring; radiation background measurements; soil samples; laboratory operations monitoring; radiation incidents; laundry monitoring; accident analysis; and industrial safety

  16. Optimization of supercritical carbon dioxide (CO2 extraction of sardine (Sardinella lemuru Bleeker oil using response surface methodology (RSM

    Directory of Open Access Journals (Sweden)

    Gedi, M. A.

    2015-06-01

    Full Text Available Oil was extracted from freeze-dried sardine (Sardinella lemur fillets using supercritical carbon dioxide (SC-CO2 and a few milliliters of ethanol were optimized with response surface methodology (RSM. The impact of extraction pressure (200–400 bars and temperature (40–70 °C were studied on the total extraction yields, ratios of Eicosapentaenoic acid (EPA and Docosahexaenoic acid (DHA. The results were compared with those of Soxhlet and modified Kinsella methods (MKM. The oils obtained using the SC-CO2 and MKM methods were significantly (P El aceite se extrae de filetes de sardinas (Sardinella lemur liofilizando, mediante dióxido de carbono supercrítico (SC-CO2 y unos mililitros de etanol, optimizándose mediante la metodología de superficie de respuesta (RSM. Se ha estudiado la influencia de la presión de extracción (200–400 bars y la temperatura (40–70 °C sobre los rendimientos de extracción total, y sobre las relaciones de ácido eicosapentaenoico (EPA y ácido docosahexaenoico (DHA. Los resultados se compararon con los obtenidos mediante extracción con Soxhlet y el método de Kinsella modificado (MKM. Los aceites obtenidos mediante SC-CO2 y métodos MKM fueron significativamente (P < 0.05 superiores en rendimientos de aceite (8,04% y 6,83%, EPA (5,43% y 5,45% y DHA (18,76% y 18,54%, respectivamente, en comparación con rendimientos mediante Soxhlet (5,10%, EPA (2,17% y DHA (06,46%. De las dos variables independientes, la presión tuvo un efecto crítico sobre el rendimiento, mientras que los porcentajes de EPA y DHA estuvieron notablemente influenciados por la temperatura. Los valores óptimos fueron para una presión de 328 bar y una temperatura de 40 °C, y sus correspondientes respuestas fueron 7,20%, 5,68% y 20,09% para el rendimiento, EPA y DHA, respectivamente. Los valores experimentales de este estudio fueron los previstos y son comparables razonablemente con sus homólogos.

  17. Predicting the indicators of the safety performance monitoring after implementation of integrated management system (IMS in a combined cycle power plant in Yazd city

    Directory of Open Access Journals (Sweden)

    F. Laal

    2015-07-01

    .Conclusion: Findings show that Cubic regression can be an appropriate to olforinvestigating the indicators trends and for their predictionin planning and monitoring the performance ofsafety unitso that the decision-making for determining the priority of organizations’ safety programs would be facilitated.

  18. Post-transcriptional regulation on a global scale: form and function of Csr/Rsm systems.

    Science.gov (United States)

    Romeo, Tony; Vakulskas, Christopher A; Babitzke, Paul

    2013-02-01

    Originally described as a repressor of gene expression in the stationary phase of growth, CsrA (RsmA) regulates primary and secondary metabolic pathways, biofilm formation, motility, virulence circuitry of pathogens, quorum sensing and stress response systems by binding to conserved sequences in its target mRNAs and altering their translation and/or turnover. While the binding of CsrA to RNA is understood at an atomic level, new mechanisms of gene activation and repression by this protein are still emerging. In the γ-proteobacteria, small non-coding RNAs (sRNAs) use molecular mimicry to sequester multiple CsrA dimers away from mRNA. In contrast, the FliW protein of Bacillus subtilis inhibits CsrA activity by binding to this protein, thereby establishing a checkpoint in flagellum morphogenesis. Turnover of CsrB and CsrC sRNAs in Escherichia coli requires a specificity protein of the GGDEF-EAL domain superfamily, CsrD, in addition to the housekeeping nucleases RNase E and PNPase. The Csr system of E. coli contains extensive autoregulatory circuitry, which governs the expression and activity of CsrA. Interaction of the Csr system with transcriptional regulatory networks results in a variety of complex response patterns. This minireview will highlight basic principles and new insights into the workings of these complex eubacterial regulatory systems. © 2012 Society for Applied Microbiology and Blackwell Publishing Ltd.

  19. [Blood glucose self monitoring].

    Science.gov (United States)

    Wascher, Thomas C; Stechemesser, Lars

    2016-04-01

    Self monitoring of blood glucose contributes to the integrated management of diabetes mellitus. It, thus, should be available for all patients with diabetes mellitus type-1 and type-2. Self monitoring of blood glucose improves patients safety, quality of life and glucose control. The current article represents the recommendations of the Austrian Diabetes Association for the use of blood glucose self monitoring according to current scientific evidence.

  20. Fernald's dilemma: Do we recycle the radioactively contaminated metals, or do we bury them?

    International Nuclear Information System (INIS)

    Yuracko, K.L.; Hadley, S.W.; Perlack, R.D.

    1996-01-01

    During the past five years, a number of U.S. Department of Energy (DOE) funded efforts have demonstrated the technical efficacy of converting various forms of radioactive scrap metal (RSM) into useable products. From the development of large accelerator shielding blocks, to the construction of low level waste containers, technology has been applied to this fabrication process in a safe and stakeholder supported manner. The potential health and safety risks to both workers and the public have been addressed. The question remains; can products be fabricated from RSM in a cost efficient and market competitive manner? This paper presents a methodology for use within DOE to evaluate the costs and benefits of recycling and reusing some RSM, rather than disposing of this RSM in an approved burial site. This life cycle decision methodology, developed by both the Oak Ridge National Laboratory (ORNL) and DOE Fernald is the focus of the following analysis

  1. Applying a life cycle decision methodology to Fernald waste management alternatives

    International Nuclear Information System (INIS)

    Yuracko, K.L.; Gresalfi, M.; Yerace, P.

    1996-01-01

    During the past five years, a number of U.S. Department of Energy (DOE) funded efforts have demonstrated the technical efficacy of converting various forms of radioactive scrap metal (RSM) into useable products. From the development of large accelerator shielding blocks, to the construction of low-level waste containers, technology has been applied to this fabrication process in a safe and stakeholder supported manner. The potential health and safety risks to both workers and the public have been addressed. The question remains: can products be fabricated from RSM in a cost efficient and market competitive manner? This paper presents a methodology for use within DOE to evaluate the costs and benefits of recycling and reusing some RSM, rather than disposing of this RSM in an approved burial site. This life cycle decision methodology, developed by both the Oak Ridge National Laboratory (ORNL) and DOE Fernald, is the focus of the following analysis

  2. Safety management in research and development organisation

    International Nuclear Information System (INIS)

    Nivedha, T.

    2016-01-01

    Health and safety is one of the most important aspects of an organizations smooth and effective functioning. It depends on the safety management, health management, motivation, leadership and training, welfare facilities, accident statistics, policy, organization and administration, hazard control and risk analysis, monitoring, statistics and reporting. Workplace accidents are increasingly common, main causes are untidiness, noise, too hot or cold environments, old or poorly maintained machines, and lack of training or carelessness of employees. One of the biggest issues facing employers today is the safety of their employees. This study aims at analyzing the occupational health and safety of Research organization in Indira Gandhi Centre for Atomic Research by gathering information on health management, safety management, motivation, leadership and training, welfare facilities, accident statistics, organization and administration, hazard control and risk analysis, monitoring, statistics and reporting. Data were collected by using questionnaires which were developed on health and safety management system. (author)

  3. Plant performance monitoring program at Krsko NPP

    International Nuclear Information System (INIS)

    Bach, B.; Kavsek, D.

    2004-01-01

    A high level of nuclear safety and plant reliability results from the complex interaction of a good design, operational safety and human performance. This is the reason for establishing a set of operational plant safety performance indicators, to enable monitoring of both plant performance and progress. Performance indicators are also used for setting challenging targets and goals for improvement, to gain additional perspective on performance relative to other plants and to provide an indication of a potential need to adjust priorities and resources to achieve improved overall plant performance. A specific indicator trend over a certain period can provide an early warning to plant management to evaluate the causes behind the observed changes. In addition to monitoring the changes and trends, it is also necessary to compare the indicators with identified targets and goals to evaluate performance strengths and weaknesses. Plant Performance Monitoring Program at Krsko NPP defines and ensures consistent collection, processing, analysis and use of predefined relevant plant operational data, providing a quantitative indication of nuclear power plant performance. When the program was developed, the conceptual framework described in IAEA TECDOC-1141 Operational Safety Performance Indicators for Nuclear Power Plants was used as its basis in order to secure that a reasonable set of quantitative indications of operational safety performance would be established. Safe, conservative, cautious and reliable operation of the Krsko NPP is a common goal for all plant personnel. It is provided by continuous assurance of both health and safety of the public and employees according to the plant policy stated in program MD-1 Notranje usmeritve in cilji NEK, which is the top plant program. Establishing a program of monitoring and assessing operational plant safety performance indicators represents effective safety culture of plant personnel.(author)

  4. Operational and environmental safety

    International Nuclear Information System (INIS)

    Anon.

    1978-01-01

    The responsibility of the DOE Office of Operational and Environmental Safety is to assure that DOE-controlled activities are conducted in a manner that will minimize risks to the public and employees and will provide protection for property and the environment. The program supports the various energy technologies by identifying and resolving safety problems; developing and issuing safety policies, standards, and criteria; assuring compliance with DOE, Federal, and state safety regulations; and establishing procedures for reporting and investigating accidents in DOE operations. Guidelines for the radiation protection of personnel; radiation monitoring at nuclear facilities; an assessment of criticality accidents by fault tree analysis; and the preparation of environmental, safety, and health standards applicable to geothermal energy development are discussed

  5. The value of Doppler LiDAR systems to monitor turbulence intensity during storm events in order to enhance aviation safety in Iceland

    Science.gov (United States)

    Yang, Shu; Nína Petersen, Guðrún; Finger, David C.

    2017-04-01

    Turbulence and wind shear are a major natural hazards for aviation safety in Iceland. The temporal and spatial scale of atmospheric turbulence is very dynamic, requiring an adequate method to detect and monitor turbulence with high resolution. The Doppler Light Detection and Ranging (LiDAR) system can provide continuous information about the wind field using the Doppler effect form emitted light signals. In this study, we use a Leosphere Windcube 200s LiDAR systems stationed near Reykjavik city Airport and at Keflavik International Airport, Iceland, to evaluate turbulence intensity by estimating eddy dissipation rate (EDR). For this purpose, we retrieved radial wind velocity observations from Velocity Azimuth Display (VAD) scans (360°scans at 15° and 75° elevation angle) to compute EDR. The method was used to monitor and characterize storm events in fall 2016 and the following winter. The preliminary result reveal that the LiDAR observations can detect and quantify atmospheric turbulence with high spatial and temporal resolution. This finding is an important step towards enhanced aviation safety in subpolar climate characterized by sever wind turbulence.

  6. URBAN-NET: A Network-based Infrastructure Monitoring and Analysis System for Emergency Management and Public Safety

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sangkeun (Matt) [ORNL; Chen, Liangzhe [ORNL; Duan, Sisi [ORNL; Chinthavali, Supriya [ORNL; Shankar, Mallikarjun (Arjun) [ORNL; Prakash, B. Aditya [Virginia Tech, Blacksburg, VA

    2016-01-01

    Abstract Critical Infrastructures (CIs) such as energy, water, and transportation are complex networks that are crucial for sustaining day-to-day commodity flows vital to national security, economic stability, and public safety. The nature of these CIs is such that failures caused by an extreme weather event or a man-made incident can trigger widespread cascading failures, sending ripple effects at regional or even national scales. To minimize such effects, it is critical for emergency responders to identify existing or potential vulnerabilities within CIs during such stressor events in a systematic and quantifiable manner and take appropriate mitigating actions. We present here a novel critical infrastructure monitoring and analysis system named URBAN-NET. The system includes a software stack and tools for monitoring CIs, pre-processing data, interconnecting multiple CI datasets as a heterogeneous network, identifying vulnerabilities through graph-based topological analysis, and predicting consequences based on what-if simulations along with visualization. As a proof-of-concept, we present several case studies to show the capabilities of our system. We also discuss remaining challenges and future work.

  7. Monitoring readiness of safety relevant devices in nuclear power plants by means of CRT-colour displays

    International Nuclear Information System (INIS)

    Haubert, R.; Stokke, R.

    1980-01-01

    The development of an information system for monitoring readiness of safety relevant devices is encouraged by the requirements of KTA-rule 3501 (DIN 25434), which states in section 4.9.1.1. 'A display shall be provided for giving a survey of the condition of the components of the reactor protection system and the active engineered safeguards including their energy and auxiliary media supplies'. In the first stage of the development which was reported at the Enlarged Halden Programme Group Meeting in Loen, Norway, 5th-9th June, 1978, only the components of parts of a BWR-protection system were considered and no display was provided. This paper outlines the next step in the development which comprises implementation of the active engineered safeguards into the system and development of a display system based on a colour CRT-screen. A prototype of this computer-based system for monitoring of protection systems has been established, and it is planned to demonstrate this prototype system using the computer equipment at GRS, Garching (orig./HP)

  8. A practical monitoring system for the structural safety of mega-trusses using wireless vibrating wire strain gauges.

    Science.gov (United States)

    Park, Hyo Seon; Lee, Hwan Young; Choi, Se Woon; Kim, Yousok

    2013-12-16

    Sensor technologies have been actively employed in structural health monitoring (SHM) to evaluate structural safety. To provide stable and real-time monitoring, a practical wireless sensor network system (WSNS) based on vibrating wire strain gauges (VWSGs) is proposed and applied to a building under construction. In this WSNS, the data measured from each VWSG are transmitted to the sensor node via a signal line and then transmitted to the master node through a short-range wireless communication module (operating on the Industrial, Scientific, and Medical (ISM) band). The master node also employs a long-range wireless communication module (Code Division Multiple Access-CDMA) to transmit the received data from the sensor node to a server located in a remote area, which enables a manager to examine the measured data in real time without any time or location restrictions. In this study, a total of 48 VWSGs, 14 sensor nodes, and seven master nodes were implemented to measure long-term strain variations of mega-trusses in an irregular large-scale building under construction. Based on strain data collected over a 16-month period, a quantitative evaluation of the construction process was performed to determine the aspects that exhibit the greatest influence on member behavior and to conduct a comparison with numerical simulation results. The effect of temperature stress on the structural elements was also analyzed. From these observations, the feasibility of a long-term WSNS based on VWSGs to evaluate the structural safety of an irregular building under construction was confirmed.

  9. A Practical Monitoring System for the Structural Safety of Mega-Trusses Using Wireless Vibrating Wire Strain Gauges

    Directory of Open Access Journals (Sweden)

    Hyo Seon Park

    2013-12-01

    Full Text Available Sensor technologies have been actively employed in structural health monitoring (SHM to evaluate structural safety. To provide stable and real-time monitoring, a practical wireless sensor network system (WSNS based on vibrating wire strain gauges (VWSGs is proposed and applied to a building under construction. In this WSNS, the data measured from each VWSG are transmitted to the sensor node via a signal line and then transmitted to the master node through a short-range wireless communication module (operating on the Industrial, Scientific, and Medical (ISM band. The master node also employs a long-range wireless communication module (Code Division Multiple Access—CDMA to transmit the received data from the sensor node to a server located in a remote area, which enables a manager to examine the measured data in real time without any time or location restrictions. In this study, a total of 48 VWSGs, 14 sensor nodes, and seven master nodes were implemented to measure long-term strain variations of mega-trusses in an irregular large-scale building under construction. Based on strain data collected over a 16-month period, a quantitative evaluation of the construction process was performed to determine the aspects that exhibit the greatest influence on member behavior and to conduct a comparison with numerical simulation results. The effect of temperature stress on the structural elements was also analyzed. From these observations, the feasibility of a long-term WSNS based on VWSGs to evaluate the structural safety of an irregular building under construction was confirmed.

  10. Traffic monitoring and modeling for Intersection Safety

    NARCIS (Netherlands)

    Pyykönen, P.; Molinier, M.; Klunder, G.A.

    2010-01-01

    The INTERSAFE-2 project aims to develop and demonstrate a Cooperative Intersection Safety System that is able to significantly reduce injury and fatal accidents at intersections. The cooperative sensor data fusion is based on state-of-the-art and advanced on-board sensors for object recognition and

  11. Monitor Beleidsimpuls Verkeersveiligheid 2014 : onderzoeksverantwoording.

    NARCIS (Netherlands)

    Weijermars, W.A.M. Goldenbeld, C. Bijleveld, F.D. & Bos, N.M.

    2015-01-01

    Monitor Policy Stimulus Road Safety 2014 : research justification. The Policy Stimulus Road Safety that was drawn up in 2012 contains 23 additional measures that the Ministry of Infrastructure and the Environment and its administrative and social partners intend to implement in order to reduce the

  12. Monitoring and diagnosis systems to improve nuclear power plant reliability and safety. Proceedings of the specialists` meeting

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    The 50 participants, representing 21 Member States (Argentina, Austria, Belgium, Canada, Czech Republic, France, Germany, Hungary, Japan, Netherlands, Norway, Russian Federation, Slovak Republic, Slovenia, Spain, Sweden, Switzerland, Turkey, Ukraine, UK and USA), reviewed the current approaches in Member States in the area of monitoring and diagnosis systems. The Meeting attempted to identify advanced techniques in the field of diagnostics of electrical and mechanical components for safety and operation improvements, reviewed actual practices and experiences related to the application of those systems with special emphasis on real occurrences, exchanged current experiences with diagnostics as a means for predictive maintenance. Refs, figs, tabs.

  13. Monitoring and diagnosis systems to improve nuclear power plant reliability and safety. Proceedings of the specialists' meeting

    International Nuclear Information System (INIS)

    1996-01-01

    The 50 participants, representing 21 Member States (Argentina, Austria, Belgium, Canada, Czech Republic, France, Germany, Hungary, Japan, Netherlands, Norway, Russian Federation, Slovak Republic, Slovenia, Spain, Sweden, Switzerland, Turkey, Ukraine, UK and USA), reviewed the current approaches in Member States in the area of monitoring and diagnosis systems. The Meeting attempted to identify advanced techniques in the field of diagnostics of electrical and mechanical components for safety and operation improvements, reviewed actual practices and experiences related to the application of those systems with special emphasis on real occurrences, exchanged current experiences with diagnostics as a means for predictive maintenance. Refs, figs, tabs

  14. 49 CFR 193.2913 - Security monitoring.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Security monitoring. 193.2913 Section 193.2913...: FEDERAL SAFETY STANDARDS Security § 193.2913 Security monitoring. Each protective enclosure and the area.... Monitoring must be by visual observation in accordance with the schedule in the security procedures under...

  15. Planning and evaluation of plant under safety aspects

    International Nuclear Information System (INIS)

    Strnad, H.

    1985-01-01

    Plant denotes a technical product characterized as being structured, complex, comprising the use of energy, and that of measuring, automatic control and monitoring systems to keep track of present, control and monitor processes. Particular attention is paid to methods of developing plant concepts, measures to exclude or detect risks, integration of safety engineering into the course of planning, safety concept and ergonomics in plant design. (DG) [de

  16. Operational safety

    International Nuclear Information System (INIS)

    Anon.

    1977-01-01

    The PNL Safety, Standards and Compliance Program contributed to the development and issuance of safety policies, standards, and criteria; for projects in the nuclear and nonnuclear areas. During 1976 the major emphasis was on developing criteria, instruments and methods to assure that radiation exposure to occupational personnel and to people in the environs of nuclear-related facilities is maintained at the lowest level technically and economically practicable. Progress in 1976 is reported on the preparation of guidelines for radiation exposure; Pu dosimetry studies; the preparation of an environmental monitoring handbook; and emergency instrumentation preparedness

  17. Reliability and safety engineering

    CERN Document Server

    Verma, Ajit Kumar; Karanki, Durga Rao

    2016-01-01

    Reliability and safety are core issues that must be addressed throughout the life cycle of engineering systems. Reliability and Safety Engineering presents an overview of the basic concepts, together with simple and practical illustrations. The authors present reliability terminology in various engineering fields, viz.,electronics engineering, software engineering, mechanical engineering, structural engineering and power systems engineering. The book describes the latest applications in the area of probabilistic safety assessment, such as technical specification optimization, risk monitoring and risk informed in-service inspection. Reliability and safety studies must, inevitably, deal with uncertainty, so the book includes uncertainty propagation methods: Monte Carlo simulation, fuzzy arithmetic, Dempster-Shafer theory and probability bounds. Reliability and Safety Engineering also highlights advances in system reliability and safety assessment including dynamic system modeling and uncertainty management. Cas...

  18. Long-Term Marine Traffic Monitoring for Environmental Safety in the Aegean Sea

    Science.gov (United States)

    Giannakopoulos, T.; Gyftakis, S.; Charou, E.; Perantonis, S.; Nivolianitou, Z.; Koromila, I.; Makrygiorgos, A.

    2015-04-01

    The Aegean Sea is characterized by an extremely high marine safety risk, mainly due to the significant increase of the traffic of tankers from and to the Black Sea that pass through narrow straits formed by the 1600 Greek islands. Reducing the risk of a ship accident is therefore vital to all socio-economic and environmental sectors. This paper presents an online long-term marine traffic monitoring work-flow that focuses on extracting aggregated vessel risks using spatiotemporal analysis of multilayer information: vessel trajectories, vessel data, meteorological data, bathymetric / hydrographic data as well as information regarding environmentally important areas (e.g. protected high-risk areas, etc.). A web interface that enables user-friendly spatiotemporal queries is implemented at the frontend, while a series of data mining functionalities extracts aggregated statistics regarding: (a) marine risks and accident probabilities for particular areas (b) trajectories clustering information (c) general marine statistics (cargo types, etc.) and (d) correlation between spatial environmental importance and marine traffic risk. Towards this end, a set of data clustering and probabilistic graphical modelling techniques has been adopted.

  19. SNL/VNIIEF Storage Monitoring Collaboration

    International Nuclear Information System (INIS)

    Barkanov, Boris P.; Bartberger, Jack C.; Blagin, Sergei V.; Croessmann, C. Dennis; Gruda, Jeffrey D.; Lupsha, Vitali A.; Moroskin, Dimitri V.; Nilsen, Curt A.

    1999-01-01

    Sandia National Laboratories (SNL) and the Russian Federal Nuclear Center-All Russian Research Institute for Experimental Physics (VNIIEF)(also know as Arzamas-16) are collaborating on ways to assure the highest standards on safety, security, and international accountability of fissile material. This includes systems used to reduce the need for human access to fissile material, reduce radiation exposure, and provide prompt safety-related information, and provide continuous international accountability information while reducing the need for intrusive, on-site visits. This paper will report on the ongoing SNL/VNIIEF efforts to develop technologies and monitoring systems to meet these goals. Specific topics covered will include: the Smart Bolt tag/seal development, development and testing of electronic sensor platforms (U.S. T-1 ESP and VNIIEF Radio Tag) for monitoring and transportation applications, the ''Magazine-to-Magazine'' remote monitoring system field test, and the ''Facility-to-Facility'' storage monitoring system field trial

  20. Measuring and improving patient safety through health information technology: The Health IT Safety Framework.

    Science.gov (United States)

    Singh, Hardeep; Sittig, Dean F

    2016-04-01

    Health information technology (health IT) has potential to improve patient safety but its implementation and use has led to unintended consequences and new safety concerns. A key challenge to improving safety in health IT-enabled healthcare systems is to develop valid, feasible strategies to measure safety concerns at the intersection of health IT and patient safety. In response to the fundamental conceptual and methodological gaps related to both defining and measuring health IT-related patient safety, we propose a new framework, the Health IT Safety (HITS) measurement framework, to provide a conceptual foundation for health IT-related patient safety measurement, monitoring, and improvement. The HITS framework follows both Continuous Quality Improvement (CQI) and sociotechnical approaches and calls for new measures and measurement activities to address safety concerns in three related domains: 1) concerns that are unique and specific to technology (e.g., to address unsafe health IT related to unavailable or malfunctioning hardware or software); 2) concerns created by the failure to use health IT appropriately or by misuse of health IT (e.g. to reduce nuisance alerts in the electronic health record (EHR)), and 3) the use of health IT to monitor risks, health care processes and outcomes and identify potential safety concerns before they can harm patients (e.g. use EHR-based algorithms to identify patients at risk for medication errors or care delays). The framework proposes to integrate both retrospective and prospective measurement of HIT safety with an organization's existing clinical risk management and safety programs. It aims to facilitate organizational learning, comprehensive 360 degree assessment of HIT safety that includes vendor involvement, refinement of measurement tools and strategies, and shared responsibility to identify problems and implement solutions. A long term framework goal is to enable rigorous measurement that helps achieve the safety

  1. Nuclear safety authority. Strategical planning 2005- 2007

    International Nuclear Information System (INIS)

    Anon.

    2006-01-01

    The Nuclear safety Authority (A.S.N.) provides, in the name of the state, the monitoring of nuclear safety and radiation protection to protect workers, patients, public and environment from the risks in relation with nuclear activities and more broadly with ionizing radiations, it contributes to citizens information in these areas. The ambition of A.S.N. is to carry out a successful, legitimate, credible nuclear monitoring, recognized by citizens and that constitutes an international reference. (N.C.)

  2. Nuclear safety in Slovak Republic. Status of safety improvements

    International Nuclear Information System (INIS)

    Toth, A.

    1999-01-01

    Status of the safety improvements at Bohunice V-1 units concerning WWER-440/V-230 design upgrading were as follows: supplementing of steam generator super-emergency feed water system; higher capacity of emergency core cooling system; supplementing of automatic links between primary and secondary circuit systems; higher level of secondary system automation. The goal of the modernization program for Bohunice V-1 units WWER-440/V-230 was to increase nuclear safety to the level of the proposals and IAEA recommendations and to reach probability goals of the reactor concerning active zone damage, leak of radioactive materials, failures of safety systems and damage shields. Upgrading program for Mochovce NPP - WWER-440/V-213 is concerned with improving the integrity of the reactor pressure vessel, steam generators 'leak before break' methods applied for the NPP, instrumentation and control of safety systems, diagnostic systems, replacement of in-core monitoring system, emergency analyses, pressurizers safety relief valves, hydrogen removal system, seismic evaluations, non-destructive testing, fire protection. Implementation of quality assurance has a special role in improvement of operational safety activities as well as safety management and safety culture, radiation protection, decommissioning and waste management and training. The Year 2000 problem is mentioned as well

  3. Report by the parliamentary mission of nuclear safety, the place and future of the sector - Intermediary report: the nuclear safety

    International Nuclear Information System (INIS)

    2011-01-01

    Notably based on visits, meetings and auditions, this report first discusses the management of nuclear safety in France and stresses how rigorous it is. It comments how the different types of risks (natural, industrial, human) are taken into account, how safety is physically present (protection barriers, warehousing, operator training) and monitored, how this organisation is always improved as far as monitoring, information and preparedness to crisis are concerned. Then, the authors present the main orientations for the strengthening of safety: by taking new major risks into account, by anticipating possible situations (for installations, for matters of civil security, for population information and sensitization), and by investing on the issue of safety (in a financial way as well as in an organisational way, or by investing on research)

  4. Facility effluent monitoring plan for the tank farm facility

    Energy Technology Data Exchange (ETDEWEB)

    Crummel, G.M.

    1998-05-18

    A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements.

  5. Facility effluent monitoring plan for 242-A Evaporator facility

    International Nuclear Information System (INIS)

    Crummel, G.M.; Gustavson, R.D.

    1993-03-01

    A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1* for any operations that involve hazardous materials and radioactive substances that could affect employee or public safety or the environment. A facility effluent monitoring plan determination was performed during Calendar Year 1991 and the evaluation showed the need for a facility effluent monitoring plan. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility effluent Monitoring Plans, WHC-EP-0438-1**. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements

  6. Risk-based safety indicators

    International Nuclear Information System (INIS)

    Sedlak, J.

    2001-12-01

    The report is structured as follows: 1. Risk-based safety indicators: Typology of risk-based indicators (RBIs); Tools for defining RBIs; Requirements for the PSA model; Data sources for RBIs; Types of risks monitored; RBIs and operational safety indicators; Feedback from operating experience; PSO model modification for RBIs; RBI categorization; RBI assessment; RBI applications; Suitable RBI applications. 2. Proposal for risk-based indicators: Acquiring information from operational experience; Method of acquiring safety relevance coefficients for the systems from a PSA model; Indicator definitions; On-line indicators. 3. Annex: Application of RBIs worldwide. (P.A.)

  7. Safe handling and monitoring of tritium in research on nuclear fusion

    International Nuclear Information System (INIS)

    Yoshida, Yoshikazu; Naruse, Yuji

    1978-01-01

    An actual condition of technique of safety handling and monitoring of tritium in the laboratory which treated a great quantity of tritium in relation to nuclear fusion, was described. With respect to the technique of safety handling of tritium, an actual condition of the technique in the U.S.A. which had wide experience in treating a great quantity of 3 H was mainly introduced, and it was helpful to a safety measure and a reduction of tritium effluence. Glovebox, hood, and other component machinery and tools for treating 3 H were also introduced briefly. As a monitoring technique, monitoring of indoor air and air exhaust by ionization chamber-type monitor for continuous monitoring of a great quantity of gaseous tritium was mentioned. Next, monitoring of a room, the surfaces of equipments, and draining, internal exposure of the individual, and monitoring of the environment were introduced. (Kanao, N.)

  8. Drug monitoring in child and adolescent psychiatry for improved efficacy and safety of psychopharmacotherapy

    Directory of Open Access Journals (Sweden)

    Fegert Jörg M

    2009-04-01

    Full Text Available Abstract Most psychotropic drugs used in the treatment of children and adolescents are applied "off label" with a direct risk of under- or overdosing and a delayed risk of long-term side effects. The selection of doses in paediatric psychiatric patients requires a consideration of pharmacokinetic parameters and the development of central nervous system, and warrants specific studies in children and adolescents. Because these are lacking for most of the psychotropic drugs applied in the Child and Adolescent and Psychiatry, therapeutic drug monitoring (TDM is a valid tool to optimise pharmacotherapy and to enable to adjust the dosage of drugs according to the characteristics of the individual patient. Multi-centre TDM studies enable the identification of age- and development-dependent therapeutic ranges of blood concentrations and facilitate a highly qualified standardized documentation in the child and adolescent health care system. In addition, they will provide data for future research on psychopharmacological treatment in children and adolescents, as a baseline for example for clinically relevant interactions with various co-medications. Therefore, a German-Austrian-Swiss "Competence Network on Therapeutic Drug Monitoring in Child and Adolescent Psychiatry" was founded 1 introducing a comprehensive internet data base for the collection of demographic, safety and efficacy data as well as blood concentrations of psychotropic drugs in children and adolescents.

  9. Mechanical analysis of flying robot for nuclear safety and security control by radiological monitoring

    International Nuclear Information System (INIS)

    Cho, Hyo Sung; Woo, Tae Ho

    2016-01-01

    Highlights: • Radiological monitoring of the NPPs site is performed by the flying robot. • The mechanics of drone is investigated in the NPPs. • Yaw and Pitch motions are simulated for the robotic behaviors. • The flying robot is analyzed for the nuclear safety and security successfully. - Abstract: The flying robot is investigated for the nuclear accident and security treatment. Several mechanics are introduced for the movement of the drone. The optimized motion of the drone should cover all areas of Nuclear Power Plants (NPPs) over the site where the circular and surmounting motions are needed with traverse of zigzag shapes. There is the Yaw motion in the circular moving and the Pitch motion in the climbing and downing against reactor facility. The fallout is calculated from the radiation concentration in the breaking part of the NPPs where the radioactive material leaks from the containment, coolant loop, plant facility and so on. The dose equivalents are obtained where the values are changeable following the random values of the y value, average wind speed, and dispersed concentration in the detection position. The simulation of new positions of x, y, and z are normalized from 0.0 to 1.0. The mechanics of flying robot produces the multidisciplinary converged technology incorporated with the aerial radiation monitoring information.

  10. Safety-I, Safety-II and Resilience Engineering.

    Science.gov (United States)

    Patterson, Mary; Deutsch, Ellen S

    2015-12-01

    In the quest to continually improve the health care delivered to patients, it is important to understand "what went wrong," also known as Safety-I, when there are undesired outcomes, but it is also important to understand, and optimize "what went right," also known as Safety-II. The difference between Safety-I and Safety-II are philosophical as well as pragmatic. Improving health care delivery involves understanding that health care delivery is a complex adaptive system; components of that system impact, and are impacted by, the actions of other components of the system. Challenges to optimal care include regular, irregular and unexampled threats. This article addresses the dangers of brittleness and miscalibration, as well as the value of adaptive capacity and margin. These qualities can, respectively, detract from or contribute to the emergence of organizational resilience. Resilience is characterized by the ability to monitor, react, anticipate, and learn. Finally, this article celebrates the importance of humans, who make use of system capabilities and proactively mitigate the effects of system limitations to contribute to successful outcomes. Copyright © 2015 Mosby, Inc. All rights reserved.

  11. The origin of high magnetic properties in (R,Zr)(Fe,Co)11.0–11.5Ti1.0–0.5Ny (y=1.0–1.4 for R=Nd, y=0 for R=Sm) compounds

    International Nuclear Information System (INIS)

    Kobayashi, K.; Suzuki, S.; Kuno, T.; Urushibata, K.; Sakuma, N.; Yano, M.; Shoji, T.; Kato, A.; Manabe, A.

    2017-01-01

    Ten alloys and nitrogenated compounds of (R,Zr)(Fe,Co) 11.0–11.5 Ti 1.0–0.5 N y (y=1.0–1.4 for R=Nd, y=0 for R=Sm) with a ThMn 12 -type structure were prepared. The average Fe–Fe interatomic distances, d(Fe–Fe), for Fe sites were calculated based on the reported atomic parameters. The hyperfine splittings (inner field (IF), in teslas) were measured by Mössbauer spectroscopy, and the IF increased with increasing d(Fe–Fe) for Fe sites, indicating a magneto-volume effect. The order of IF magnitude in Fe sites was Fe(8i)>Fe(8j)>Fe(8f) in all alloys. Co substitution for Fe sites, (Fe 0.75 Co 0.25 ), increased the IF by 25% for the R=Nd alloy and 15% for the R=Sm alloy. Decreasing Ti content from −Ti 1.0 to −Ti 0.5 , which increased the Fe and Co content, preserved the ThMn 12 structure with Zr substitution for R(2a) sites, and caused a slight increase in the IF of 2% for the R=Nd alloy and 7% for the R=Sm alloy. Nitrogenation, where N was introduced into the 2b sites, also increased IF in R=Nd alloys, by 23% for the Co- and Zr-free alloys, NdFe 11 Ti 1.0 N 1.5 , and by 7% for the Co-containing, (Nd 0.7 Zr 0.3 ) (Fe 0.75 Co 0.25 ) 11.5 Ti 0.5 N 1.3 alloy. The IF values of the R=Nd alloys were slightly larger than those of the R=Sm alloys. In conclusion, the magneto-volume effect was clearly observed at the Fe sites, and Co substitution into Fe sites and nitrogenation (R=Nd alloys) compensated for the increased IF. Increasing the Fe and Co fractions also increased IF slightly. - Highlights: • Average distances of Fe–Fe (d(Fe–Fe)) were calculated using lattice constants. • Hyperfine fields (IF) in Fe sites were measured using Mössbauer spectroscopy. • Relationship between d(Fe–Fe) and IF at each Fe site was obtained. • Co substitution and N introduction effects on IF was also measured. • Magneto-volume effect is main reason of IF augmentation in Fe sites.

  12. Study on a monitoring strategy to support decision making for geological repository closure

    International Nuclear Information System (INIS)

    Suyama, Yasuhiro; Tanabe, Hiromi; Eto, Jiro; Yoshimura, Kimitaka

    2010-01-01

    Japan currently plans to dispose of high-level radioactive wastes (vitrified HLWs) produced from the reprocessing of spent nuclear fuel in deep geological formations, in order to isolate the radioactive wastes from the human environment for tens of thousands of years. Such a geological repository must be designed to ensure operational safety and post-closure safety. Then, following the closure of the geological repository, post-closure safety will be provided by an engineered barrier system (EBS) and a natural barrier system (NBS) without relying on monitoring or institutional control. However, from a technical standpoint, monitoring has been required during backfilling in current studies. Additionally, there has been strong social pressure to continue monitoring during all the phases including post-closure. On the basis of the current situations, a monitoring strategy for geological disposal must be studied to ensure the long term safety of geological disposal. Focusing on decision making for geological repository closure, the authors have created a basic logical structure for the decision making process with the principles for ensuring safety and have developed a monitoring strategy based on the logical structure. The monitoring strategy is founded on three key aspects: the role of monitoring, boundary conditions of monitoring at the time of decision making, and a methodology for monitoring planning. Then, the monitoring strategy becomes a starting point of monitoring planning during site characterization, construction, operation and staged closure, as well as post-closure with institutional control, and of social science studies. (author)

  13. Federal Radiological Monitoring and Assessment Center Monitoring Manual Volume 1, Operations

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Aerial Measurement Systems

    2012-07-31

    The Monitoring division is primarily responsible for the coordination and direction of: Aerial measurements to delineate the footprint of radioactive contaminants that have been released into the environment. Monitoring of radiation levels in the environment; Sampling to determine the extent of contaminant deposition in soil, water, air and on vegetation; Preliminary field analyses to quantify soil concentrations or depositions; and Environmental and personal dosimetry for FRMAC field personnel, during a Consequence Management Response Team (CMRT) and Federal Radiological Monitoring and Assessment Center (FRMAC) response. Monitoring and sampling techniques used during CM/FRMAC operations are specifically selected for use during radiological emergencies where large numbers of measurements and samples must be acquired, analyzed, and interpreted in the shortest amount of time possible. In addition, techniques and procedures are flexible so that they can be used during a variety of different scenarios; e.g., accidents involving releases from nuclear reactors, contamination by nuclear waste, nuclear weapon accidents, space vehicle reentries, or contamination from a radiological dispersal device. The Monitoring division also provides technicians to support specific Health and Safety Division activities including: The operation of the Hotline; FRMAC facility surveys; Assistance with Health and Safety at Check Points; and Assistance at population assembly areas which require support from the FRMAC. This volume covers deployment activities, initial FRMAC activities, development and implementation of the monitoring and assessment plan, the briefing of field teams, and the transfer of FRMAC to the EPA.

  14. Annual report on occupational safety 1989

    International Nuclear Information System (INIS)

    1990-01-01

    This report presents detailed information on occupational safety relating to BNFL's employees for 1989 and data compared with the previous year. Routine monitoring, non-radiological safety and 'incidents' are discussed and 'statutory' whole-body exposures, nuclear incidents, lost-time accidents, and types of injury are tabulated. (author)

  15. Air and radiation monitoring stations

    CERN Multimedia

    AUTHOR|(SzGeCERN)582709

    2015-01-01

    CERN has around 100 monitoring stations on and around its sites. New radiation measuring stations, capable of detecting even lower levels of radiation, were installed in 2014. Two members of HE-SEE group (Safety Engineering and Environment group) in front of one of the new monitoring stations.

  16. Cryogenic safety organisation at CERN

    CERN Multimedia

    CERN. Geneva

    2016-01-01

    With Safety being a top priority of CERN’s general policy, the Organisation defines and implements a Policy that sets out the general principles governing Safety at CERN. To the end of the attainment of said Safety objectives, the organic units (owners/users of the equipment) are assigned the responsibility for the implementation of the CERN Safety Policy at all levels of the organization, whereas the Health and Safety and Environmental Protection Unit (HSE) has the role of providing assistance for the implementation of the Safety Policy, and a monitoring role related to the implementation of continuous improvement of Safety, compliance with the Safety Rules and the handling of emergency situations. This talk will elaborate on the roles, responsibilities and organisational structure of the different stakeholders within the Organization with regards to Safety, and in particular to cryogenic safety. The roles of actors of particular importance such as the Cryogenic Safety Officers (CSOs) and the Cryogenic Sa...

  17. Leadership for safety: industrial experience.

    Science.gov (United States)

    Flin, R; Yule, S

    2004-12-01

    The importance of leadership for effective safety management has been the focus of research attention in industry for a number of years, especially in energy and manufacturing sectors. In contrast, very little research into leadership and safety has been carried out in medical settings. A selective review of the industrial safety literature for leadership research with possible application in health care was undertaken. Emerging findings show the importance of participative, transformational styles for safety performance at all levels of management. Transactional styles with attention to monitoring and reinforcement of workers' safety behaviours have been shown to be effective at the supervisory level. Middle managers need to be involved in safety and foster open communication, while ensuring compliance with safety systems. They should allow supervisors a degree of autonomy for safety initiatives. Senior managers have a prime influence on the organisation's safety culture. They need to continuously demonstrate a visible commitment to safety, best indicated by the time they devote to safety matters.

  18. Prevalence and trends of drugged driving in Canada.

    Science.gov (United States)

    Robertson, Robyn D; Mainegra Hing, Marisela; Pashley, Charlotte R; Brown, Steve W; Vanlaar, Ward G M

    2017-02-01

    This study evaluates prevalence and trends in drugged driving in Canada based on multiple indicators collected from the Road Safety Monitor (RSM) and Canada's National Fatality Database maintained by the Traffic Injury Research Foundation (TIRF). The objective of this paper is to identify the state of drug-positive driving in Canada, as well as to make comparisons with data from previous years to determine whether changes have occurred. Available data from the RSM on self-reported drugged driving behaviours were collected and analyzed using multivariate techniques in various years spanning from 2002 to 2015. Data from TIRF's National Fatality Database from 2000 to 2012 were also analyzed to evaluate trends and prevalence of drugs in fatally injured drivers across Canada. Additionally, differences among drugged drivers with respect to gender and age were studied. Analyses of the RSM data and of the National Fatality Database showed that, as a whole, the prevalence of drugged driving has remained relatively stable over the past decade, with some changes noticed in specific years for some drug types. Specifically from the RSM, there was a 62.5% increase from the 1.6% of drivers reporting driving within two hours of using marijuana in 2013 to 2.6% in 2015. The analyses of the fatality data revealed a 16.9% increase in the percentage of fatally injured drivers testing positive for drugs between 2000 and 2012 (from 33.56% to 39.24%). Cocaine-positive fatally injured drivers increased from 3.6% in 2000 to 6.2% in 2012. Similarly, marijuana-positive fatally injured drivers increased from 12.8% in 2000 to 19.7% in 2012. Results showed varying characteristics with respect to gender and age among self-reported and fatally injured drugged drivers. Drugged driving behaviours remain prevalent among Canadian drivers and drugs continue to be found in over one-third of tested fatally injured drivers. Although self-reported behaviours have neither decreased nor increased overall in

  19. Advances in safety related maintenance

    International Nuclear Information System (INIS)

    2000-03-01

    The maintenance of systems, structures and components in nuclear power plants (NPPs) plays an important role in assuring their safe and reliable operation. Worldwide, NPP maintenance managers are seeking to reduce overall maintenance costs while maintaining or improving the levels of safety and reliability. Thus, the issue of NPP maintenance is one of the most challenging aspects of nuclear power generation. There is a direct relation between safety and maintenance. While maintenance alone (apart from modifications) will not make a plant safer than its original design, deficient maintenance may result in either an increased number of transients and challenges to safety systems or reduced reliability and availability of safety systems. The confidence that NPP structures, systems and components will function as designed is ultimately based on programmes which monitor both their reliability and availability to perform their intended safety function. Because of this, approaches to monitor the effectiveness of maintenance are also necessary. An effective maintenance programme ensures that there is a balance between the improvement in component reliability to be achieved and the loss of component function due to maintenance downtime. This implies that the safety level of an NPP should not be adversely affected by maintenance performed during operation. The nuclear industry widely acknowledges the importance of maintenance in NPP safety and operation and therefore devotes great efforts to develop techniques, methods and tools to aid in maintenance planning, follow-up and optimization, and in assuring the effectiveness of maintenance

  20. A Methodology To Incorporate The Safety Culture Into Probabilistic Safety Assessments

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sunghyun; Kim, Namyeong; Jae, Moosung [Hanyang University, Seoul (Korea, Republic of)

    2015-10-15

    In order to incorporate organizational factors into PSA, a methodology needs to be developed. Using the AHP to weigh organizational factors as well as the SLIM to rate those factors, a methodology is introduced in this study. The safety issues related to nuclear safety culture have occurred increasingly. The quantification tool has to be developed in order to include the organizational factor into Probabilistic Safety Assessments. In this study, the state-of-the-art for the organizational evaluation methodologies has been surveyed. This study includes the research for organizational factors, maintenance process, maintenance process analysis models, a quantitative methodology using Analytic Hierarchy Process, Success Likelihood Index Methodology. The purpose of this study is to develop a methodology to incorporate the safety culture into PSA for obtaining more objective risk than before. The organizational factor considered in nuclear safety culture might affect the potential risk of human error and hardware-failure. The safety culture impact index to monitor the plant safety culture can be assessed by applying the developed methodology into a nuclear power plant.

  1. A Methodology To Incorporate The Safety Culture Into Probabilistic Safety Assessments

    International Nuclear Information System (INIS)

    Park, Sunghyun; Kim, Namyeong; Jae, Moosung

    2015-01-01

    In order to incorporate organizational factors into PSA, a methodology needs to be developed. Using the AHP to weigh organizational factors as well as the SLIM to rate those factors, a methodology is introduced in this study. The safety issues related to nuclear safety culture have occurred increasingly. The quantification tool has to be developed in order to include the organizational factor into Probabilistic Safety Assessments. In this study, the state-of-the-art for the organizational evaluation methodologies has been surveyed. This study includes the research for organizational factors, maintenance process, maintenance process analysis models, a quantitative methodology using Analytic Hierarchy Process, Success Likelihood Index Methodology. The purpose of this study is to develop a methodology to incorporate the safety culture into PSA for obtaining more objective risk than before. The organizational factor considered in nuclear safety culture might affect the potential risk of human error and hardware-failure. The safety culture impact index to monitor the plant safety culture can be assessed by applying the developed methodology into a nuclear power plant

  2. New technologies for item monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Abbott, J.A. [EG & G Energy Measurements, Albuquerque, NM (United States); Waddoups, I.G. [Sandia National Labs., Albuquerque, NM (United States)

    1993-12-01

    This report responds to the Department of Energy`s request that Sandia National Laboratories compare existing technologies against several advanced technologies as they apply to DOE needs to monitor the movement of material, weapons, or personnel for safety and security programs. The authors describe several material control systems, discuss their technologies, suggest possible applications, discuss assets and limitations, and project costs for each system. The following systems are described: WATCH system (Wireless Alarm Transmission of Container Handling); Tag system (an electrostatic proximity sensor); PANTRAK system (Personnel And Material Tracking); VRIS (Vault Remote Inventory System); VSIS (Vault Safety and Inventory System); AIMS (Authenticated Item Monitoring System); EIVS (Experimental Inventory Verification System); Metrox system (canister monitoring system); TCATS (Target Cueing And Tracking System); LGVSS (Light Grid Vault Surveillance System); CSS (Container Safeguards System); SAMMS (Security Alarm and Material Monitoring System); FOIDS (Fiber Optic Intelligence & Detection System); GRADS (Graded Radiation Detection System); and PINPAL (Physical Inventory Pallet).

  3. New technologies for item monitoring

    International Nuclear Information System (INIS)

    Abbott, J.A.; Waddoups, I.G.

    1993-12-01

    This report responds to the Department of Energy's request that Sandia National Laboratories compare existing technologies against several advanced technologies as they apply to DOE needs to monitor the movement of material, weapons, or personnel for safety and security programs. The authors describe several material control systems, discuss their technologies, suggest possible applications, discuss assets and limitations, and project costs for each system. The following systems are described: WATCH system (Wireless Alarm Transmission of Container Handling); Tag system (an electrostatic proximity sensor); PANTRAK system (Personnel And Material Tracking); VRIS (Vault Remote Inventory System); VSIS (Vault Safety and Inventory System); AIMS (Authenticated Item Monitoring System); EIVS (Experimental Inventory Verification System); Metrox system (canister monitoring system); TCATS (Target Cueing And Tracking System); LGVSS (Light Grid Vault Surveillance System); CSS (Container Safeguards System); SAMMS (Security Alarm and Material Monitoring System); FOIDS (Fiber Optic Intelligence ampersand Detection System); GRADS (Graded Radiation Detection System); and PINPAL (Physical Inventory Pallet)

  4. Safety Precautions. Child Health and Safety Series (Module I).

    Science.gov (United States)

    Iscoe, Louise; And Others

    This manual for parents and child care personnel in day care homes and centers provides guidelines and information on indoor and outdoor safety precautions, emergency preparation and first aid. Contents focus on monitoring arrivals and departures, prevention of suffocation and strangulation, control of pets and other animals, preventing and…

  5. Clinician-Driven Design of VitalPAD–An Intelligent Monitoring and Communication Device to Improve Patient Safety in the Intensive Care Unit

    Science.gov (United States)

    Flohr, Luisa; Beaudry, Shaylene; Johnson, K Taneille; West, Nicholas; Burns, Catherine M; Ansermino, J Mark; Dumont, Guy A; Wensley, David; Skippen, Peter

    2018-01-01

    The pediatric intensive care unit (ICU) is a complex environment, in which a multidisciplinary team of clinicians (registered nurses, respiratory therapists, and physicians) continually observe and evaluate patient information. Data are provided by multiple, and often physically separated sources, cognitive workload is high, and team communication can be challenging. Our aim is to combine information from multiple monitoring and therapeutic devices in a mobile application, the VitalPAD, to improve the efficiency of clinical decision-making, communication, and thereby patient safety. We observed individual ICU clinicians, multidisciplinary rounds, and handover procedures for 54 h to identify data needs, workflow, and existing cognitive aid use and limitations. A prototype was developed using an iterative participatory design approach; usability testing, including general and task-specific feedback, was obtained from 15 clinicians. Features included map overviews of the ICU showing clinician assignment, patient status, and respiratory support; patient vital signs; a photo-documentation option for arterial blood gas results; and team communication and reminder functions. Clinicians reported the prototype to be an intuitive display of vital parameters and relevant alerts and reminders, as well as a user-friendly communication tool. Future work includes implementation of a prototype, which will be evaluated under simulation and real-world conditions, with the aim of providing ICU staff with a monitoring device that will improve their daily work, communication, and decision-making capacity. Mobile monitoring of vital signs and therapy parameters might help improve patient safety in wards with single-patient rooms and likely has applications in many acute and critical care settings. PMID:29552425

  6. Autonomous monitoring unit, signs and registration for Cobalt-60 irradiator safety system

    Energy Technology Data Exchange (ETDEWEB)

    Baldaconi, Ricardo H.; Costa, Fabio E. da, E-mail: ricardohovacker@hotmail.com, E-mail: fecosta@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    The Cobalt-60 irradiator of IPEN / CNEN, a category IV facility, has a security system for inter locking doors or exposure of radioactive sources made simultaneously by a programmable logic controller (PLC) model S7- 200 from Siemens and a relay logic. From a set of information, the both systems work together opening doors or exposing the sources. All incoming and outgoing information are sent serially via EIA232 communication to a personal computer with Windows® platform for a supervisory program which provides besides a monitoring the entire process by a synoptic table on the computer screen, also keeps records of all events on the computer's hard drive. The electronic management has proven to be efficient and has not produced any failure that had compromised the safety. The PLC along with the relay logic has always taken the right decisions ensuring proper radiation protection of operators and the integrity of radioactive sources, but it presented over the years of operation (beginning in 2004) less than a dozen flaws in system event log. The deficiency was found between the process of sending events via serial communication (EIA232) to the supervisory program. When failure occurs in a very short time, the PLC always took the right decision, but the registration process that had to go through the Windows® timeshare lost the information. This work aimed to build a standalone electronics connect the inputs and outputs of the security system, fully optocoupled to avoid any interference to the security system. It records each event on a memory card, waits for the right decision of the security system and in case of an incorrect decision an independent alarm notifies its own synoptic picture, and sends a text message to a group of defined cell phones. The circuit uses two microcontrollers called 'main' and 'secondary'. The main is responsible for the control and monitoring of peripheral inputs and outputs of the security system. The main is

  7. Autonomous monitoring unit, signs and registration for Cobalt-60 irradiator safety system

    International Nuclear Information System (INIS)

    Baldaconi, Ricardo H.; Costa, Fabio E. da

    2015-01-01

    The Cobalt-60 irradiator of IPEN / CNEN, a category IV facility, has a security system for inter locking doors or exposure of radioactive sources made simultaneously by a programmable logic controller (PLC) model S7- 200 from Siemens and a relay logic. From a set of information, the both systems work together opening doors or exposing the sources. All incoming and outgoing information are sent serially via EIA232 communication to a personal computer with Windows® platform for a supervisory program which provides besides a monitoring the entire process by a synoptic table on the computer screen, also keeps records of all events on the computer's hard drive. The electronic management has proven to be efficient and has not produced any failure that had compromised the safety. The PLC along with the relay logic has always taken the right decisions ensuring proper radiation protection of operators and the integrity of radioactive sources, but it presented over the years of operation (beginning in 2004) less than a dozen flaws in system event log. The deficiency was found between the process of sending events via serial communication (EIA232) to the supervisory program. When failure occurs in a very short time, the PLC always took the right decision, but the registration process that had to go through the Windows® timeshare lost the information. This work aimed to build a standalone electronics connect the inputs and outputs of the security system, fully optocoupled to avoid any interference to the security system. It records each event on a memory card, waits for the right decision of the security system and in case of an incorrect decision an independent alarm notifies its own synoptic picture, and sends a text message to a group of defined cell phones. The circuit uses two microcontrollers called 'main' and 'secondary'. The main is responsible for the control and monitoring of peripheral inputs and outputs of the security system. The main is

  8. Real-time pathogen monitoring during enrichment: a novel nanotechnology-based approach to food safety testing.

    Science.gov (United States)

    Weidemaier, Kristin; Carruthers, Erin; Curry, Adam; Kuroda, Melody; Fallows, Eric; Thomas, Joseph; Sherman, Douglas; Muldoon, Mark

    2015-04-02

    We describe a new approach for the real-time detection and identification of pathogens in food and environmental samples undergoing culture. Surface Enhanced Raman Scattering (SERS) nanoparticles are combined with a novel homogeneous immunoassay to allow sensitive detection of pathogens in complex samples such as stomached food without the need for wash steps or extensive sample preparation. SERS-labeled immunoassay reagents are present in the cultural enrichment vessel, and the signal is monitored real-time through the wall of the vessel while culture is ongoing. This continuous monitoring of pathogen load throughout the enrichment process enables rapid, hands-free detection of food pathogens. Furthermore, the integration of the food pathogen immunoassay directly into the enrichment vessel enables fully biocontained food safety testing, thereby significantly reducing the risk of contaminating the surrounding environment with enriched pathogens. Here, we present experimental results showing the detection of E. coli, Salmonella, or Listeria in several matrices (raw ground beef, raw ground poultry, chocolate milk, tuna salad, spinach, brie cheese, hot dogs, deli turkey, orange juice, cola, and swabs and sponges used to sample a stainless steel surface) using the SERS system and demonstrate the accuracy of the approach compared to plating results. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Facility effluent monitoring plan for the fast flux test facility

    International Nuclear Information System (INIS)

    Nickels, J.M.; Dahl, N.R.

    1992-11-01

    A facility effluent monitoring plan is required by the US Department of Energy in US Department of Energy Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could affect employee or public safety or the environment. A Facility Effluent Monitoring Plan determination was performed during calendar year 1991 and the evaluation requires the need for a facility effluent monitoring plan. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements

  10. Usability styles of the plant safety monitoring and assesment system, PLASMA

    International Nuclear Information System (INIS)

    Green, M.; Hornaes, A.; Hulsund, J.E.; Vegh, J.; Major, Cs.; Lipcsei, S.; Borbely, S.

    2001-01-01

    Development of the PLASMA (Plant Safety Monitoring and Assessment) system was started in 1998 in the framework of an international Research and Development project supported by OECD/NEA. The objective of this project was to develop an on-line information system to support VVER reactor operators during the execution of symptom-based Emergency Operating Procedures (EOPs), with the Paks NPP in Hungary as the target plant. In connection with the installation of the PLASMA system at Paks NPP it was decided to perform a usability study of the system through interviewing NPP operators after they had completed a short training course on the PLASMA system and used it during a validation and training session in the training simulator at Paks. This report describes the basic process used in preparations and execution of the usability studies, including methods for gathering information and analysis of the findings from the validation. As a general conclusion from the usability studies it can be stated that the PLASMA system received very favourable ratings from the operators. User satisfaction was generally rated highly and comments from operators were positive. This is particularly encouraging considering the relatively short introduction and experience that the operators had with the system at the time of the-evaluation. (Author)

  11. Finansiell Bootstrapping i SME : en kvantitativ studie om hur ett starkt socialt och affärsmässigt nätverk påverkar valet av bootstrappingmetoder

    OpenAIRE

    Nilsson, Ida; Sacic, Zehra

    2016-01-01

    Syftet med denna kandidatuppsats är se hur ett starkt socialt och affärsmässigt nätverk påverkar valet av bootstrappingmetoder i små och medelstora företag (SME). Detta eftersom SME står för 99,9 procent av samtliga företag på den svenska marknaden och därmed är betydelsefulla för landets ekonomiska tillväxt och sysselsättning. Däremot möter SME svårigheter vid extern finansiering av sin verksamhet. SME kompenserar detta genom att engagera sig i olika ”bootstrappingaktiviteter”. Bootstrapping...

  12. Optimization of extraction parameters of PTP1β (protein tyrosine phosphatase 1β), inhibitory polyphenols, and anthocyanins from Zea mays L. using response surface methodology (RSM).

    Science.gov (United States)

    Hwang, Seung Hwan; Kwon, Shin Hwa; Wang, Zhiqiang; Kim, Tae Hyun; Kang, Young-Hee; Lee, Jae-Yong; Lim, Soon Sung

    2016-08-26

    Protein tyrosine phosphatase expressed in insulin-sensitive tissues (such as liver, muscle, and adipose tissue) has a key role in the regulation of insulin signaling and pathway activation, making protein tyrosine phosphatase a promising target for the treatment of type 2 diabetes mellitus and obesity and response surface methodology (RSM) is an effective statistical technique for optimizing complex processes using a multi-variant approach. In this study, Zea mays L. (Purple corn kernel, PCK) and its constituents were investigated for protein tyrosine phosphatase 1β (PTP1β) inhibitory activity including enzyme kinetic study and to improve total yields of anthocyanins and polyphenols, four extraction parameters, including temperature, time, solid-liquid ratio, and solvent volume, were optimized by RSM. Isolation of seven polyphenols and five anthocyanins was achieved by PTP1β assay. Among them, cyanidin-3-(6"malonylglucoside) and 3'-methoxyhirsutrin showed the highest PTP1β inhibition with IC50 values of 54.06 and 64.04 μM, respectively and 4.52 mg gallic acid equivalent/g (GAE/g) of total polyphenol content (TPC) and 43.02 mg cyanidin-3-glucoside equivalent/100 g (C3GE/100g) of total anthocyanin content (TAC) were extracted at 40 °C for 8 h with a 33 % solid-liquid ratio and a 1:15 solvent volume. Yields were similar to predictions of 4.58 mg GAE/g of TPC and 42.28 mg C3GE/100 g of TAC. These results indicated that PCK and 3'-methoxyhirsutrin and cyanidin-3-(6"malonylglucoside) might be active natural compounds and could be apply by optimizing of extraction process using response surface methodology.

  13. Establishing a national biological laboratory safety and security monitoring program.

    Science.gov (United States)

    Blaine, James W

    2012-12-01

    The growing concern over the potential use of biological agents as weapons and the continuing work of the Biological Weapons Convention has promoted an interest in establishing national biological laboratory biosafety and biosecurity monitoring programs. The challenges and issues that should be considered by governments, or organizations, embarking on the creation of a biological laboratory biosafety and biosecurity monitoring program are discussed in this article. The discussion focuses on the following questions: Is there critical infrastructure support available? What should be the program focus? Who should be monitored? Who should do the monitoring? How extensive should the monitoring be? What standards and requirements should be used? What are the consequences if a laboratory does not meet the requirements or is not willing to comply? Would the program achieve the results intended? What are the program costs? The success of a monitoring program can depend on how the government, or organization, responds to these questions.

  14. MCO Monitoring Plan

    International Nuclear Information System (INIS)

    SEXTON, R.A.

    2000-01-01

    The basis for development of the Multi-Canister Overpack (MCO) Monitoring Plan was established in HNF-3312, MCO Monitoring Activity Description (Sexton 1998), with the following specific objectives: The safety of Spent Nuclear Fuel (SNF) Project processes for retrieving, packaging, handling, conditioning, and storing the N Reactor spent nuclear fuel has been demonstrated by conservative analyses, as compiled in the project safety basis and licensing documentation. Appropriate quality assurance and independent checking of engineering, fabrication, and construction are being applied, and there will be in-process monitoring and verification of MCO loading and conditioning actions. Once the MCOs have been placed in storage, there is no safety requirement, regulatory requirement, or precedent to monitor them. Although not required, a monitoring program which would acquire data for use by Process Engineering is considered valuable for several reasons (Sexton 1998): Good engineering practice--Acquiring data at a reasonable cost that may be useful in developing a fuller understanding of the behavior of an engineered system is good engineering practice. Actual data on full scale MCOs is otherwise unavailable--Previous investigations have been limited to small fuel samples or simulant prototypes and have been relatively short in duration. MCO monitoring can provide data on large loads of actual fuel, in full-scale configuration, over longer time periods. Additional knowledge of the fuel type may prove valuable in future analyses or applications. On that basis, a program with two components was planned: The pressure/temperature/gas composition relationships will be observed in a limited number of MCOs during the first two years in storage. The remaining MCOs will incorporate a simple means to confirm at any time in the future, that internal pressure of the MCO is not high enough to threaten its structural integrity. The MCOs are likely to be stored for 40 years or longer

  15. Safety Management at PUSPATI TRIGA Reactor (RTP)

    International Nuclear Information System (INIS)

    Ligam, A.S.; Zarina Masood; Ahmad Nabil Abdul Rahim

    2011-01-01

    Adequate safety measures and precautions, which follow relevant safety standards and procedures, should be in place so that personnel safety is assured. Nevertheless, the public, visitor, contractor or anyone who wishes to enter or be in the reactor building should be well informed with the safety measures applied. Furthermore, these same elements of safety are also applied to other irradiation facilities within the premises of Nuclear Malaysia. This paper will describes and explains current safety management system being enforced especially in the TRIGA PUSPATI Reactor (RTP) namely radiation monitoring system, safety equipment, safe work instruction, and interconnected internal and external health, safety and security related departments. (author)

  16. Health physics, safety and medical services report for 1989

    International Nuclear Information System (INIS)

    Burt, A.K.; Bird, R.W.

    1990-09-01

    The Health Physics, Safety and Medical Services Report for Harwell Laboratory for 1989 includes data on the monitoring of the working environment, personnel monitoring, radiological incidents, disposal of radioactive waste and protection of the public. Work on emergency planning, non-radiological health and safety, occupational hygiene, operations support is also discussed. Finally the medical services available and the medical examinations performed are described. (UK)

  17. Development of a safety parameter supervision system for Angra-1

    International Nuclear Information System (INIS)

    Silva, R.A. da; Thome Filho, Z.D.; Schirru, R.; Martinez, A.S.; Oliveira, L.F.S. de

    1986-01-01

    The Safety Parameter Supervision System (SSPS) which is a computerized system for monitoring essential parameters in real time, determining the safety status and emergency procedures for returning normal reactor operation, in case of an anomaly occurrence, is presented. The SSPS consists of three sub-systems: Integrated parameter monitoring system which gives to operators an integrated vision of values of a parameter set, able to detect any deviation of normal reactor operation; safety critical function system which evaluates safety status in terms of a safety critical function set appointed in advance, and in case of violation of any critical function, it initiates the adequate emergency procedure to return normal operation; and safety parameter computer system which carries out the arquirement of analogic and digital control signals of nuclear power plant. (M.C.K.) [pt

  18. Implementation science for ambulatory care safety: a novel method to develop context-sensitive interventions to reduce quality gaps in monitoring high-risk patients.

    Science.gov (United States)

    McDonald, Kathryn M; Su, George; Lisker, Sarah; Patterson, Emily S; Sarkar, Urmimala

    2017-06-24

    Missed evidence-based monitoring in high-risk conditions (e.g., cancer) leads to delayed diagnosis. Current technological solutions fail to close this safety gap. In response, we aim to demonstrate a novel method to identify common vulnerabilities across clinics and generate attributes for context-flexible population-level monitoring solutions for widespread implementation to improve quality. Based on interviews with staff in otolaryngology, pulmonary, urology, breast, and gastroenterology clinics at a large urban publicly funded health system, we applied journey mapping to co-develop a visual representation of how patients are monitored for high-risk conditions. Using a National Academies framework and context-sensitivity theory, we identified common systems vulnerabilities and developed preliminary concepts for improving the robustness for monitoring patients with high-risk conditions ("design seeds" for potential solutions). Finally, we conducted a face validity and prioritization assessment of the design seeds with the original interviewees. We identified five high-risk situations for potentially consequential diagnostic delays arising from suboptimal patient monitoring. All situations related to detection of cancer (head and neck, lung, prostate, breast, and colorectal). With clinic participants we created 5 journey maps, each representing specialty clinic workflow directed at evidence-based monitoring. System vulnerabilities common to the different clinics included challenges with: data systems, communications handoffs, population-level tracking, and patient activities. Clinic staff ranked 13 design seeds (e.g., keep patient list up to date, use triggered notifications) addressing these vulnerabilities. Each design seed has unique evaluation criteria for the usefulness of potential solutions developed from the seed. We identified and ranked 13 design seeds that characterize situations that clinicians described 'wake them up at night', and thus could reduce

  19. Optimization of the production conditions of the lipase produced by Bacillus cereus from rice flour through Plackett-Burman Design (PBD) and response surface methodology (RSM).

    Science.gov (United States)

    Vasiee, Alireza; Behbahani, Behrooz Alizadeh; Yazdi, Farideh Tabatabaei; Moradi, Samira

    2016-12-01

    In this study, the screening of lipase positive bacteria from rice flour was carried out by Rhodamin B agar plate method. Bacillus cereus was identified by 16S rDNA method. Screening of the appropriate variables and optimization of the lipase production was performed using Plackett-Burman design (PBD) and response surface methodology (RSM). Among the isolated bacteria, an aerobic Bacillus cereus strain was recognized as the best lipase-producing bacteria (177.3 ± 20 U/ml). Given the results, the optimal enzyme production conditions were achieved with coriander seed extract (CSE)/yeast extract ratio of 16.9 w/w, olive oil (OO) and MgCl 2 concentration of 2.37 g/L and 24.23 mM, respectively. In these conditions, the lipase activity (LA) was predicted 343 U/mL that was approximately close to the predicted value (324 U/mL), which was increased 1.83 fold LA compared with the non-optimized lipase. The kinetic parameters of V max and K m for the lipase were measured 0.367 μM/min.mL and 5.3 mM, respectively. The lipase producing Bacillus cereus was isolated and RSM was used for the optimization of enzyme production. The CSE/yeast extract ratio of 16.9 w/w, OO concentration of 2.37 g/L and MgCl 2 concentration of 24.23 mM, were found to be the optimal conditions of the enzyme production process. LA at optimal enzyme production conditions was observed 1.83 times more than the non-optimal conditions. Ultimately, it can be concluded that the isolated B. cereus from rice flour is a proper source of lipase. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Instrumentation and control systems important to safety in nuclear power plants. Safety guide

    International Nuclear Information System (INIS)

    2005-01-01

    principles should be applied, on the basis of a method of classifying systems by their importance to safety. I and C systems important to safety are I and C systems that are part of a safety group and I and C systems whose malfunction or failure could lead to radiation exposure of site personnel or members of the public. Examples of such systems are: the reactor protection system, reactor control systems, systems to monitor and control normal reactor cooling, systems to monitor and control emergency power supplies, containment isolation systems. The IAEA's Technical Reports Series No. 387 presents an overview of concepts and examples of systems discussed in this Safety Guide and may provide useful background material for some users

  1. Evaluation of the costs and benefits of recycling radioactively contaminated scrap metal

    International Nuclear Information System (INIS)

    Durman, E.C.; Tsirigotis, P.; MacKinney, J.A.

    1995-01-01

    The U.S. Environmental Protection Agency (EPA) is evaluating the economic and technical issues associated with the potential recycling of radioactive scrap metals (RSM). These metals, usually only slightly contaminated, originate primarily from the decommissioning and decontamination (D and D) of federal facilities, licensees of the Nuclear Regulatory Commission, and certain unlicensed industries. EPA conducted a study entitled Analysis of the Potential Recycling of Department of Energy Radioactive Scrap Metal, September 6, 1994, for the U.S. Department of Energy (DOE) to provide information and tools to DOE for assessing DOE's problem with RSM from the D and D of their sites. EPA is now initiating an evaluation of RSM recycling to support a recycling regulation. Although the study prepared for DOE will provide a useful start for the regulatory analysis, additional information must be gathered to analyze the impacts of a recycling regulation that will apply to all potential generators of RSM. This paper summarizes cost-benefit issues related to an RSM recycling regulatory analysis, including: the quantity of potentially recyclable contaminated metals; costs of disposal at federal and private waste repositories; all potential environmental, health, and safety, and market impacts; and the potential for adverse effects on radio-sensitive industries. (author)

  2. Health Monitor for Multitasking, Safety-Critical, Real-Time Software

    Science.gov (United States)

    Zoerner, Roger

    2011-01-01

    Health Manager can detect Bad Health prior to a failure occurring by periodically monitoring the application software by looking for code corruption errors, and sanity-checking each critical data value prior to use. A processor s memory can fail and corrupt the software, or the software can accidentally write to the wrong address and overwrite the executing software. This innovation will continuously calculate a checksum of the software load to detect corrupted code. This will allow a system to detect a failure before it happens. This innovation monitors each software task (thread) so that if any task reports "bad health," or does not report to the Health Manager, the system is declared bad. The Health Manager reports overall system health to the outside world by outputting a square wave signal. If the square wave stops, this indicates that system health is bad or hung and cannot report. Either way, "bad health" can be detected, whether caused by an error, corrupted data, or a hung processor. A separate Health Monitor Task is started and run periodically in a loop that starts and stops pending on a semaphore. Each monitored task registers with the Health Manager, which maintains a count for the task. The registering task must indicate if it will run more or less often than the Health Manager. If the task runs more often than the Health Manager, the monitored task calls a health function that increments the count and verifies it did not go over max-count. When the periodic Health Manager runs, it verifies that the count did not go over the max-count and zeroes it. If the task runs less often than the Health Manager, the periodic Health Manager will increment the count. The monitored task zeroes the count, and both the Health Manager and monitored task verify that the count did not go over the max-count.

  3. RTP Radiation Monitoring System

    International Nuclear Information System (INIS)

    Alfred, S.L.; Mohd Fairus Abdul Farid; Ahmad Nabil Abdul Rahim; Nurhayati Ramli

    2015-01-01

    Radiation Monitoring System aiming to limiting dose exposed to personnel to the lowest level referring to the concept of ALARA (As Low As Reasonably Achievable). Atomic Energy Licensing (Basic Safety Radiation Protection) Regulation 2010 (Act 304) is a baseline to control employee and public radiation protection program and guideline, as well as to meet the requirement of the Occupational Safety and Health 1994 (Act 514). (author)

  4. Facility effluent monitoring plan for the plutonium-uranium extraction facility

    International Nuclear Information System (INIS)

    Nickels, J.M.; Geiger, J.L.

    1992-11-01

    A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. A facility effluent monitoring plan determination was performed during Calendar Year 1991 and the evaluation requires the need for a facility effluent monitoring plan. This document is prepared using the specific guidelines identified. in. A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements

  5. Radiological safety and control

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Sea Young; Yoo, Y S; Lee, J C; Lee, T Y; Lee, J L; Kim, B W; Lee, B J; Chung, K K; Chung, R I; Kim, J S; Lee, H S; Han, Y D; Lee, J I; Lee, K C; Yoon, J H; Sul, C W; Kim, C K; Yoon, K S; Seo, K W; Yoon, Y C [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1996-01-01

    This report describes the annual results of radiological safety and control program of 1995. This program consists of working area monitoring including HANARO, personnel radiation monitoring, education for radiation protection. As a result, the objectives of radiation protection have been achieved satisfactorily through the activities mentioned above. Also, the calibration services were provided to insure accurate radiation measurement in the radiation working places. 21 figs., 39 tabs., 5 refs. (Author) .new.

  6. The Competence Promoting by NNSA for Keeping High Level Nuclear Safety: The Corner Stone of the Nuclear Safety Regulation Edifice

    International Nuclear Information System (INIS)

    Hu, L.

    2016-01-01

    Facing the fast development of the nuclear power industry and the application of radioactive sources, The MEP(NNSA) is endeavoured to promoting its competency, including: complementing the law system, training and recruiting staff to keep a capable team, constructing the R&D base to keep the basic capability, promoting safety culture both for the industry and the regulator. After the Fukushima nuclear accident, the MEP(NNSA) planned to construct R&D base, in which the Platform Nuclear Safety Monitoring and Emergency Responding, the Platform of Safety Technology of PWR Testing, the Laboratory of Safety Management Technology of Nuclear Waste Verification, the Laboratory of Environmental Radiation Monitoring and the Center of International Cooperation are included. On the other hand, the MEP(NNSA) issued Chinese nuclear safety culture policy declaration in 2014, and carried out a large scale Specialized Action for Nuclear Safety Promotion to promote the nuclear safety culture both for the industry and herself. For the nuclear regulator, It is essential to conduct the competence promoting by both “hardware” and “software”, the former is the material foundation of regulation authority, which will be effectively functioning under the facilitating of the latter. (author)

  7. Optimization of biostimulant for bioremediation of contaminated coastal sediment by response surface methodology (RSM) and evaluation of microbial diversity by pyrosequencing.

    Science.gov (United States)

    Subha, Bakthavachallam; Song, Young Chae; Woo, Jung Hui

    2015-09-15

    The present study aims to optimize the slow release biostimulant ball (BSB) for bioremediation of contaminated coastal sediment using response surface methodology (RSM). Different bacterial communities were evaluated using a pyrosequencing-based approach in contaminated coastal sediments. The effects of BSB size (1-5cm), distance (1-10cm) and time (1-4months) on changes in chemical oxygen demand (COD) and volatile solid (VS) reduction were determined. Maximum reductions of COD and VS, 89.7% and 78.8%, respectively, were observed at a 3cm ball size, 5.5cm distance and 4months; these values are the optimum conditions for effective treatment of contaminated coastal sediment. Most of the variance in COD and VS (0.9291 and 0.9369, respectively) was explained in our chosen models. BSB is a promising method for COD and VS reduction and enhancement of SRB diversity. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Basic principles for occupational radiation monitoring

    International Nuclear Information System (INIS)

    1987-01-01

    This Safety Guide sets forth the objectives of an adequate strategy for monitoring internal and external radiation exposures of workers. It covers individual monitoring, and workplace monitoring to the extent required for assessment and control of individual radiation doses. The responsibilities of authorities for organizing the monitoring of radiation workers are discussed, and brief descriptions are given of the rules governing the implementation of monitoring methods. The general principles to be considered in selecting instrumentation and appropriate monitoring techniques are described, as well as calibrating techniques, methods of record keeping and related aspects

  9. Visualization of Safety Assessment Result Using GIS in SITES

    International Nuclear Information System (INIS)

    Yun, Bong-Yo; Park, Joo Wan; Park, Se-Moon; Kim, Chang-Lak

    2006-01-01

    Site Information and Total Environmental database management System (SITES) is an integrated program for overall data analysis, environmental monitoring, and safety analysis that are produced from the site investigation and environmental assessment of the relevant nuclear facility. SITES is composed of three main modules such as Site Environment Characterization database for Unified and Reliable Evaluation system (SECURE), Safety Assessment INTegration system (SAINT) and Site Useful Data Analysis and ALarm system (SUDAL). The visualization function of safety assessment and environmental monitoring results is designed. This paper is to introduce the visualization design method using Geographic Information System (GIS) for SITES

  10. 三层网络监控的新型煤矿井下电力安全监控系统研究%Three layer of network monitoring of new coal mine underground power safety monitoring system research

    Institute of Scientific and Technical Information of China (English)

    伍龙; 吴永祥; 周孟然

    2011-01-01

    利用嵌入式监控分站作为中继站,智能电力装置面向现场设备进行实时数据采集,结合地面微机管理系统,形成了三层网络监控的新型煤矿井下电力安全监控系统。介绍了系统硬件设计,并完成了系统软件设计和测试,结果表明:监控系统运行正常、动作可靠、灵敏度高、显示正确无误、各项指标均达到了设计要求,实现了三级网络整定保护定值和远程监控,提高了煤矿井下电力安全监控系统的实时数据处理能力。%Use embedded monitoring RACES as Repeaters,intelligent power device for on-site equipment real-time data acquisition,micro-processor management on the ground,formed three layer of network monitoring of new coal mine underground power safety monitoring system.This paper introduces the hardware design,and completed the system software design and test,the result shows that the monitoring system operating normally,reliable operation,high sensitivity,display correct,all indexes meet the design requirements,improve the power safety monitoring system coal mine underground real-time data processing ability.

  11. Facility effluent monitoring plan for the B plant

    International Nuclear Information System (INIS)

    Lesser, J.E.

    1994-09-01

    A facility effluent monitoring plan is required by the U.S. Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438-1. This facility effluent monitoring plant assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. This facility effluent monitoring plan shall ensure long-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated every three years

  12. Individual monitoring

    International Nuclear Information System (INIS)

    2004-01-01

    This Practical Radiation Technical Manual is one of a series which has been designed to provide guidance on radiological protection for employers, Radiation Protection Officers, managers and other technically competent persons who have a responsibility to ensure the safety of employees working with ionizing radiation. The Manual may be used together with the appropriate IAEA Practical Radiation Safety Manual to provide adequate training, instruction or information on individual monitoring for all employees engaged in work with ionizing radiations. Sources of ionizing radiation have a large number of applications in the workplace. The exposures of the individual workers involved may need to be routinely monitored and records kept of their cumulative radiation doses. There are also occasions when it is necessary to retrospectively determine a dose which may have been received by a worker. This Manual explains the basic terminology associated with individual monitoring and describes the principal types of dosimeters and other related techniques and their application in the workplace. The Manual will be of most benefit if it forms part of more comprehensive training or is supplemented by the advice of a qualified expert in radiation protection. Most of the dosimeters and techniques described in this Manual can only be provided by qualified experts

  13. A Real-Time Construction Safety Monitoring System for Hazardous Gas Integrating Wireless Sensor Network and Building Information Modeling Technologies.

    Science.gov (United States)

    Cheung, Weng-Fong; Lin, Tzu-Hsuan; Lin, Yu-Cheng

    2018-02-02

    In recent years, many studies have focused on the application of advanced technology as a way to improve management of construction safety management. A Wireless Sensor Network (WSN), one of the key technologies in Internet of Things (IoT) development, enables objects and devices to sense and communicate environmental conditions; Building Information Modeling (BIM), a revolutionary technology in construction, integrates database and geometry into a digital model which provides a visualized way in all construction lifecycle management. This paper integrates BIM and WSN into a unique system which enables the construction site to visually monitor the safety status via a spatial, colored interface and remove any hazardous gas automatically. Many wireless sensor nodes were placed on an underground construction site and to collect hazardous gas level and environmental condition (temperature and humidity) data, and in any region where an abnormal status is detected, the BIM model will alert the region and an alarm and ventilator on site will start automatically for warning and removing the hazard. The proposed system can greatly enhance the efficiency in construction safety management and provide an important reference information in rescue tasks. Finally, a case study demonstrates the applicability of the proposed system and the practical benefits, limitations, conclusions, and suggestions are summarized for further applications.

  14. Analysis and design on airport safety information management system

    Directory of Open Access Journals (Sweden)

    Yan Lin

    2017-01-01

    Full Text Available Airport safety information management system is the foundation of implementing safety operation, risk control, safety performance monitor, and safety management decision for the airport. The paper puts forward the architecture of airport safety information management system based on B/S model, focuses on safety information processing flow, designs the functional modules and proposes the supporting conditions for system operation. The system construction is helpful to perfecting the long effect mechanism driven by safety information, continually increasing airport safety management level and control proficiency.

  15. Advancing perinatal patient safety through application of safety science principles using health IT.

    Science.gov (United States)

    Webb, Jennifer; Sorensen, Asta; Sommerness, Samantha; Lasater, Beth; Mistry, Kamila; Kahwati, Leila

    2017-12-19

    The use of health information technology (IT) has been shown to promote patient safety in Labor and Delivery (L&D) units. The use of health IT to apply safety science principles (e.g., standardization) to L&D unit processes may further advance perinatal safety. Semi-structured interviews were conducted with L&D units participating in the Agency for Healthcare Research and Quality's (AHRQ's) Safety Program for Perinatal Care (SPPC) to assess units' experience with program implementation. Analysis of interview transcripts was used to characterize the process and experience of using health IT for applying safety science principles to L&D unit processes. Forty-six L&D units from 10 states completed participation in SPPC program implementation; thirty-two (70%) reported the use of health IT as an enabling strategy for their local implementation. Health IT was used to improve standardization of processes, use of independent checks, and to facilitate learning from defects. L&D units standardized care processes through use of electronic health record (EHR)-based order sets and use of smart pumps and other technology to improve medication safety. Units also standardized EHR documentation, particularly related to electronic fetal monitoring (EFM) and shoulder dystocia. Cognitive aids and tools were integrated into EHR and care workflows to create independent checks such as checklists, risk assessments, and communication handoff tools. Units also used data from EHRs to monitor processes of care to learn from defects. Units experienced several challenges incorporating health IT, including obtaining organization approval, working with their busy IT departments, and retrieving standardized data from health IT systems. Use of health IT played an integral part in the planning and implementation of SPPC for participating L&D units. Use of health IT is an encouraging approach for incorporating safety science principles into care to improve perinatal safety and should be incorporated

  16. A Methodology for Evaluating Quantitative Nuclear Safety Culture Impact

    Energy Technology Data Exchange (ETDEWEB)

    Han, Kiyoon; Jae, Moosung [Hanyang University, Seoul (Korea, Republic of)

    2015-05-15

    Through several accidents of NPPs including the Fukushima Daiichi in 2011 and Chernobyl accidents in 1986, nuclear safety culture has been emphasized in reactor safety world-widely. In Korea, KHNP evaluates the safety culture of NPP itself. KHNP developed the principles of the safety culture in consideration of the international standards. A questionnaire and interview questions are also developed based on these principles and it is used for evaluating the safety culture. However, existing methodology to evaluate the safety culture has some disadvantages. First, it is difficult to maintain the consistency of the assessment. Second, the period of safety culture assessment is too long (every two years) so it has limitations in preventing accidents occurred by a lack of safety culture. Third, it is not possible to measure the change in the risk of NPPs by weak safety culture since it is not clearly explains the effect of safety culture on the safety of NPPs. In this study, Safety Culture Impact Assessment Model (SCIAM) is developed overcoming these disadvantages. In this study, SCIAM which overcoming disadvantages of exiting safety culture assessment method is developed. SCIAM uses SCII to monitor the statues of the safety culture periodically and also uses RCDF to quantify the safety culture impact on NPP's safety. It is significant that SCIAM represents the standard of the healthy nuclear safety culture, while the exiting safety culture assessment presented only vulnerability of the safety culture of organization. SCIAM might contribute to monitoring the level of safety culture periodically and, to improving the safety of NPP.

  17. A Methodology for Evaluating Quantitative Nuclear Safety Culture Impact

    International Nuclear Information System (INIS)

    Han, Kiyoon; Jae, Moosung

    2015-01-01

    Through several accidents of NPPs including the Fukushima Daiichi in 2011 and Chernobyl accidents in 1986, nuclear safety culture has been emphasized in reactor safety world-widely. In Korea, KHNP evaluates the safety culture of NPP itself. KHNP developed the principles of the safety culture in consideration of the international standards. A questionnaire and interview questions are also developed based on these principles and it is used for evaluating the safety culture. However, existing methodology to evaluate the safety culture has some disadvantages. First, it is difficult to maintain the consistency of the assessment. Second, the period of safety culture assessment is too long (every two years) so it has limitations in preventing accidents occurred by a lack of safety culture. Third, it is not possible to measure the change in the risk of NPPs by weak safety culture since it is not clearly explains the effect of safety culture on the safety of NPPs. In this study, Safety Culture Impact Assessment Model (SCIAM) is developed overcoming these disadvantages. In this study, SCIAM which overcoming disadvantages of exiting safety culture assessment method is developed. SCIAM uses SCII to monitor the statues of the safety culture periodically and also uses RCDF to quantify the safety culture impact on NPP's safety. It is significant that SCIAM represents the standard of the healthy nuclear safety culture, while the exiting safety culture assessment presented only vulnerability of the safety culture of organization. SCIAM might contribute to monitoring the level of safety culture periodically and, to improving the safety of NPP

  18. Optimization and modeling of spot welding parameters with simultaneous multiple response consideration using multi objective Taguchi method and RSM

    Energy Technology Data Exchange (ETDEWEB)

    Muhammad, Nora Siah; Manurung Yupiter HP; Hafidzi, Moham Mad; Abas, Sun Haji Kiyai; Tham, Ghalib; Haru Man, Esa [Universiti Teknologi MARA (UiTM), Selangor (Malaysia)

    2012-08-15

    This paper presents an alternative method to optimize process parameters of resistance spot welding (RSW) towards weld zone development. The optimization approach attempts to consider simultaneously the multiple quality characteristics, namely weld nugget and heat affected zone (HAZ), using multi objective Taguchi method (MTM). The experimental study was conducted for plate thickness of 1.5mm under different welding current, weld time and hold time. The optimum welding parameters were investigated using the Taguchi method with L9 orthogonal array. The optimum value was analyzed by means of MTM, which involved the calculation of total normalized quality loss (TNQL) and multi signal to noise ratio (MSNR). A significant level of the welding parameters was further obtained by using analysis of variance (ANOVA). Furthermore, the first order model for predicting the weld zone development is derived by using response surface methodology (RSM). Based on the experimental confirmation test, the proposed method can be effectively applied to estimate the size of weld zone, which can be used to enhance and optimized the welding performance in RSW or other application.

  19. Optimization and modeling of spot welding parameters with simultaneous multiple response consideration using multi objective Taguchi method and RSM

    International Nuclear Information System (INIS)

    Muhammad, Nora Siah; Manurung Yupiter HP; Hafidzi, Moham Mad; Abas, Sun Haji Kiyai; Tham, Ghalib; Haru Man, Esa

    2012-01-01

    This paper presents an alternative method to optimize process parameters of resistance spot welding (RSW) towards weld zone development. The optimization approach attempts to consider simultaneously the multiple quality characteristics, namely weld nugget and heat affected zone (HAZ), using multi objective Taguchi method (MTM). The experimental study was conducted for plate thickness of 1.5mm under different welding current, weld time and hold time. The optimum welding parameters were investigated using the Taguchi method with L9 orthogonal array. The optimum value was analyzed by means of MTM, which involved the calculation of total normalized quality loss (TNQL) and multi signal to noise ratio (MSNR). A significant level of the welding parameters was further obtained by using analysis of variance (ANOVA). Furthermore, the first order model for predicting the weld zone development is derived by using response surface methodology (RSM). Based on the experimental confirmation test, the proposed method can be effectively applied to estimate the size of weld zone, which can be used to enhance and optimized the welding performance in RSW or other application

  20. Optimization extraction conditions for improving phenolic content and antioxidant activity in Berberis asiatica fruits using response surface methodology (RSM).

    Science.gov (United States)

    Belwal, Tarun; Dhyani, Praveen; Bhatt, Indra D; Rawal, Ranbeer Singh; Pande, Veena

    2016-09-15

    This study for the first time designed to optimize the extraction of phenolic compounds and antioxidant potential of Berberis asiatica fruits using response surface methodology (RSM). Solvent selection was done based on the preliminary experiments and a five-factors-three-level, Central Composite Design (CCD). Extraction temperature (X1), sample to solvent ratio (X3) and solvent concentration (X5) significantly affect response variables. The quadratic model well fitted for all the responses. Under optimal extraction conditions, the dried fruit sample mixed with 80% methanol having 3.0 pH in a ratio of 1:50 and the mixture was heated at 80 °C for 30 min; the measured parameters was found in accordance with the predicted values. High Performance Liquid Chromatography (HPLC) analysis at optimized condition reveals 6 phenolic compounds. The results suggest that optimization of the extraction conditions is critical for accurate quantification of phenolics and antioxidants in Berberis asiatica fruits, which may further be utilized for industrial extraction procedure. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Safety-net concept - an extra step in environmental monitoring

    International Nuclear Information System (INIS)

    Sage, L.E.; Kachur, M.; Shank, K.E.; Palms, J.

    1990-01-01

    In 1979, a monitoring program, designed by the Academy of Natural Sciences, was implemented at the Pennsylvania Power and Light Company nuclear station in rural Pennsylvania. The program had three objectives: (1) provide an independent level of public confidence concerning the ecological significance of radionuclides released to the environment; (2) understand the transport and fate of radionuclides in the environment; (3) develop monitoring methods that are responsive to cumulative radiation in the environment. This program focuses on biological receptors that concentrate radionuclides and increase detection sensitivity in all segments of the environment. The aquatic environment is monitored in the conventional manner by sampling fish tissues and in a less traditional manner by sampling the finer river sediments and periphytic diatoms. The terrestrial environment is monitored by sampling home vegetable gardens, forest vegetation, lichens, and game mammals. A primary goal is to establish ecological linkages, for example, between radionuclides, tree leaves, leaf litter, humus, and fungi. These linkages extend, through food, to game mammals, thence to humans. Eight years of experimental results are presented

  2. Ensuring safety in monitored retrievable storage

    International Nuclear Information System (INIS)

    Guenther, R.J.; Gilbert, E.R.; Slate, S.C.; Devine, J.R.; Kreid, D.K.; Partain, W.L.

    1984-01-01

    The behaviour of spent fuel in dry storage will be one of the principal considerations in the design of monitored retrievable storage (MRS) facilities. Reliable predictive tools for extrapolating fuel performance during long storage periods can provide guidance and criteria for the design and operation of MRS facilities. This article reviews the results of recent efforts to predict the degradation of spent fuel in MRS and summarises the expected performance of other waste forms during storage. (author)

  3. Facility Effluent Monitoring Plan for the Plutonium Finishing Plant

    International Nuclear Information System (INIS)

    FRAZIER, T.P.

    1999-01-01

    A facility effluent monitoring plan is required by the U. S. Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether these systems are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. To ensure the long-range integrity of the effluent monitoring systems, an update to this facility effluent monitoring plan is required whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document is reviewed annually even if there are no operational changes, and is updated, at a minimum, every 3 years

  4. Patient safety goals for the proposed Federal Health Information Technology Safety Center.

    Science.gov (United States)

    Sittig, Dean F; Classen, David C; Singh, Hardeep

    2015-03-01

    The Office of the National Coordinator for Health Information Technology is expected to oversee creation of a Health Information Technology (HIT) Safety Center. While its functions are still being defined, the center is envisioned as a public-private entity focusing on promotion of HIT related patient safety. We propose that the HIT Safety Center leverages its unique position to work with key administrative and policy stakeholders, healthcare organizations (HCOs), and HIT vendors to achieve four goals: (1) facilitate creation of a nationwide 'post-marketing' surveillance system to monitor HIT related safety events; (2) develop methods and governance structures to support investigation of major HIT related safety events; (3) create the infrastructure and methods needed to carry out random assessments of HIT related safety in complex HCOs; and (4) advocate for HIT safety with government and private entities. The convening ability of a federally supported HIT Safety Center could be critically important to our transformation to a safe and effective HIT enabled healthcare system. © The Author 2014. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  5. A new concept of safety parameter display system

    International Nuclear Information System (INIS)

    Martinez, A.S.; Oliveira, L.F.S. de; Schirru, R.; Thome Filho, Z.D.; Silva, R.A. da.

    1986-07-01

    A general description of Angra-1 Parameter Display System (SSPA), a real time and on-line computerized monitoring system for the parameters related to the power plant safety is presented. This system has the main purpose of diminish the load on the Angra-1 power plant operators at an emergency event by supplying them with the additional tools serving as the basis for a prompt identification of the accident. The SSPA is a kind of safety parameter display system whose concept was introduced after Three Mile Island accident in USA. The SSPA comprises two nuclear applications independently considered. They are included into the Parameters Monitoring Integrated System (SIMP) and the safety critical function system (SFCS). (Author) [pt

  6. Monitoring Quality of Biotherapeutic Products Using Multivariate Data Analysis.

    Science.gov (United States)

    Rathore, Anurag S; Pathak, Mili; Jain, Renu; Jadaun, Gaurav Pratap Singh

    2016-07-01

    Monitoring the quality of pharmaceutical products is a global challenge, heightened by the implications of letting subquality drugs come to the market on public safety. Regulatory agencies do their due diligence at the time of approval as per their prescribed regulations. However, product quality needs to be monitored post-approval as well to ensure patient safety throughout the product life cycle. This is particularly complicated for biotechnology-based therapeutics where seemingly minor changes in process and/or raw material attributes have been shown to have a significant effect on clinical safety and efficacy of the product. This article provides a perspective on the topic of monitoring the quality of biotech therapeutics. In the backdrop of challenges faced by the regulatory agencies, the potential use of multivariate data analysis as a tool for effective monitoring has been proposed. Case studies using data from several insulin biosimilars have been used to illustrate the key concepts.

  7. 10 CFR 36.55 - Personnel monitoring.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Personnel monitoring. 36.55 Section 36.55 Energy NUCLEAR REGULATORY COMMISSION LICENSES AND RADIATION SAFETY REQUIREMENTS FOR IRRADIATORS Operation of Irradiators § 36.55 Personnel monitoring. (a) Irradiator operators shall wear a personnel dosimeter that is...

  8. Acoustic Techniques for Structural Health Monitoring

    Science.gov (United States)

    Frankenstein, B.; Augustin, J.; Hentschel, D.; Schubert, F.; Köhler, B.; Meyendorf, N.

    2008-02-01

    Future safety and maintenance strategies for industrial components and vehicles are based on combinations of monitoring systems that are permanently attached to or embedded in the structure, and periodic inspections. The latter belongs to conventional nondestructive evaluation (NDE) and can be enhanced or partially replaced by structural health monitoring systems. However, the main benefit of this technology for the future will consist of systems that can be differently designed based on improved safety philosophies, including continuous monitoring. This approach will increase the efficiency of inspection procedures at reduced inspection times. The Fraunhofer IZFP Dresden Branch has developed network nodes, miniaturized transmitter and receiver systems for active and passive acoustical techniques and sensor systems that can be attached to or embedded into components or structures. These systems have been used to demonstrate intelligent sensor networks for the monitoring of aerospace structures, railway systems, wind energy generators, piping system and other components. Material discontinuities and flaws have been detected and monitored during full scale fatigue testing. This paper will discuss opportunities and future trends in nondestructive evaluation and health monitoring based on new sensor principles and advanced microelectronics. It will outline various application examples of monitoring systems based on acoustic techniques and will indicate further needs for research and development.

  9. Design for safety: theoretical framework of the safety aspect of BIM system to determine the safety index

    Directory of Open Access Journals (Sweden)

    Ai Lin Evelyn Teo

    2016-12-01

    Full Text Available Despite the safety improvement drive that has been implemented in the construction industry in Singapore for many years, the industry continues to report the highest number of workplace fatalities, compared to other industries. The purpose of this paper is to discuss the theoretical framework of the safety aspect of a proposed BIM System to determine a Safety Index. An online questionnaire survey was conducted to ascertain the current workplace safety and health situation in the construction industry and explore how BIM can be used to improve safety performance in the industry. A safety hazard library was developed based on the main contributors to fatal accidents in the construction industry, determined from the formal records and existing literature, and a series of discussions with representatives from the Workplace Safety and Health Institute (WSH Institute in Singapore. The results from the survey suggested that the majority of the firms have implemented the necessary policies, programmes and procedures on Workplace Safety and Health (WSH practices. However, BIM is still not widely applied or explored beyond the mandatory requirement that building plans should be submitted to the authorities for approval in BIM format. This paper presents a discussion of the safety aspect of the Intelligent Productivity and Safety System (IPASS developed in the study. IPASS is an intelligent system incorporating the buildable design concept, theory on the detection, prevention and control of hazards, and the Construction Safety Audit Scoring System (ConSASS. The system is based on the premise that safety should be considered at the design stage, and BIM can be an effective tool to facilitate the efforts to enhance safety performance. IPASS allows users to analyse and monitor key aspects of the safety performance of the project before the project starts and as the project progresses.

  10. Drug safety in pregnancy - monitoring congenital anomalies

    NARCIS (Netherlands)

    Morgan, Margery; De Jong-Van Den Berg, Lolkje T. W.; Jordan, Sue

    Aim This paper outlines research into the causes of congenital anomalies, and introduces a pan-European study. The potential roles of nurses and midwives in this area are illustrated by a case report. Background Since the thalidomide disaster, use of drugs in pregnancy has been carefully monitored

  11. Critical function monitoring system algorithm development

    International Nuclear Information System (INIS)

    Harmon, D.L.

    1984-01-01

    Accurate critical function status information is a key to operator decision-making during events threatening nuclear power plant safety. The Critical Function Monitoring System provides continuous critical function status monitoring by use of algorithms which mathematically represent the processes by which an operating staff would determine critical function status. This paper discusses in detail the systematic design methodology employed to develop adequate Critical Function Monitoring System algorithms

  12. Supervisory monitoring system in nuclear power plants

    International Nuclear Information System (INIS)

    Ciftcioglu, O.; Turkcan, E.

    1997-01-01

    Monitoring of a power plant is one of the essential tasks during operation and the computer-based implementations are nowadays seemingly quite mature. However, presently these are still not satisfactory enough to meet the high standards to the licensing requirements and they are mostly not truly integrated to the plant's design-based monitoring system. This is basically due to the robustness problem as the majority of the methods are not robust enough for the monitoring of the safety parameter set in a plant or intelligent supervision. Therefore, a supervisory monitoring system (SMS) in a plant is necessary to supervise the monitoring tasks: determining the objectives to be obtained and finding the means to support them. SMS deals with the changing plant status and the coordination of the information flow among the monitoring subunits. By means of these robustness and consistency in monitoring is achieved. The paper will give the guidelines of knowledge and data management techniques in a framework of robust comprehensive and coordinated monitoring which is presented as supervisory monitoring. Such a high level monitoring serves for consistent and immediate actions in fault situations while this particularly has vital importance in preventing imminent severe accidents next to the issues of recognition of the monitoring procedures for licensing and enhanced plant safety. (author). 8 refs, 5 figs

  13. Research oil guidelines for safety review of category 2 waste disposal

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-08-15

    Safety confirmation items and monitoring items for engineered barriers were compiled, considering the current technical status and monitoring plan for the simulated subsurface disposal and its test facilities. In order to develop the guidelines of the safety review for the disposal of LLW generated from RI facilities and research facilities, technical issues relating toxic substances were surveyed. (author)

  14. An Integrated Environment Monitoring System for Underground Coal Mines—Wireless Sensor Network Subsystem with Multi-Parameter Monitoring

    OpenAIRE

    Zhang, Yu; Yang, Wei; Han, Dongsheng; Kim, Young-Il

    2014-01-01

    Environment monitoring is important for the safety of underground coal mine production, and it is also an important application of Wireless Sensor Networks (WSNs). We put forward an integrated environment monitoring system for underground coal mine, which uses the existing Cable Monitoring System (CMS) as the main body and the WSN with multi-parameter monitoring as the supplementary technique. As CMS techniques are mature, this paper mainly focuses on the WSN and the interconnection between t...

  15. Computer monitoring system for pilot plant nuclear criticality facility (solution ZPR)

    International Nuclear Information System (INIS)

    Hua Xiaokang; Liang Huiping

    1999-01-01

    The system is used for the Solution Zero Power Reactor physics measurement and safety monitoring. Its software modularization design enables multi-task real-time monitoring and off-time data processing. The system is labor/time saving to experimenters and will enhance the experiment precision and the reactor operation safety performance

  16. Regulatory Oversight of Safety Culture in Finland: A Systemic Approach to Safety

    International Nuclear Information System (INIS)

    Oedewald, P.; Väisäsvaara, J.

    2016-01-01

    In Finland the Radiation and Nuclear Safety Authority STUK specifies detailed regulatory requirements for good safety culture. Both the requirements and the practical safety culture oversight activities reflect a systemic approach to safety: the interconnections between the technical, human and organizational factors receive special attention. The conference paper aims to show how the oversight of safety culture can be integrated into everyday oversight activities. The paper also emphasises that the scope of the safety culture oversight is not specific safety culture activities of the licencees, but rather the overall functioning of the licence holder or the new build project organization from safety point of view. The regulatory approach towards human and organizational factors and safety culture has evolved throughout the years of nuclear energy production in Finland. Especially the recent new build projects have highlighted the need to systematically pay attention to the non-technical aspects of safety as it has become obvious how the HOF issues can affect the design processes and quality of construction work. Current regulatory guides include a set of safety culture related requirements. The requirements are binding to the licence holders and they set both generic and specific demands on the licencee to understand, monitor and to develop safety culture of their own organization but also that of their supplier network. The requirements set for the licence holders has facilitated the need to develop the regulator’s safety culture oversight practices towards a proactive and systemic approach.

  17. 30 CFR 57.5002 - Exposure monitoring.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Exposure monitoring. 57.5002 Section 57.5002 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... monitoring. Dust, gas, mist, and fume surveys shall be conducted as frequently as necessary to determine the...

  18. Leadership Actions to Improve Nuclear Safety Culture

    International Nuclear Information System (INIS)

    Clewett, L.K.

    2016-01-01

    The challenge many leaders face is how to effectively implement and then utilise the results of Safety Culture surveys. Bruce Power has recently successfully implemented changes to the Safety Culture survey process including how corrective actions were identified and implemented. The actions taken in response to the latest survey have proven effective with step change performance noted. Nuclear Safety is a core value for Bruce Power. Nuclear Safety at Bruce Power is based on the following four pillars: reactor safety, industrial safety, radiological safety and environmental safety. Processes and practices are in place to achieve a healthy Nuclear Safety Culture within Bruce Power such that nuclear safety is the overriding priority. This governance is based on industry leading practices which monitor, asses and take action to drive continual improvements in the Nuclear Safety Culture within Bruce Power.

  19. New set of Chemical Safety rules

    CERN Multimedia

    HSE Unit

    2011-01-01

    A new set of four Safety Rules was issued on 28 March 2011: Safety Regulation SR-C ver. 2, Chemical Agents (en); General Safety Instruction GSI-C1, Prevention and Protection Measures (en); General Safety Instruction GSI-C2, Explosive Atmospheres (en); General Safety Instruction GSI-C3, Monitoring of Exposure to Hazardous Chemical Agents in Workplace Atmospheres (en). These documents form part of the CERN Safety Rules and are issued in application of the “Staff Rules and Regulations” and of document SAPOCO 42. These documents set out the minimum requirements for the protection of persons from risks to their occupational safety and health arising, or likely to arise, from the effects of hazardous chemical agents that are present in the workplace or used in any CERN activity. Simultaneously, the HSE Unit has published seven Safety Guidelines and six Safety Forms. These documents are available from the dedicated Web page “Chemical, Cryogenic and Biological Safety&...

  20. Benchmarking Global Food Safety Performances: The Era of Risk Intelligence.

    Science.gov (United States)

    Valleé, Jean-Charles Le; Charlebois, Sylvain

    2015-10-01

    Food safety data segmentation and limitations hamper the world's ability to select, build up, monitor, and evaluate food safety performance. Currently, there is no metric that captures the entire food safety system, and performance data are not collected strategically on a global scale. Therefore, food safety benchmarking is essential not only to help monitor ongoing performance but also to inform continued food safety system design, adoption, and implementation toward more efficient and effective food safety preparedness, responsiveness, and accountability. This comparative study identifies and evaluates common elements among global food safety systems. It provides an overall world ranking of food safety performance for 17 Organisation for Economic Co-Operation and Development (OECD) countries, illustrated by 10 indicators organized across three food safety risk governance domains: risk assessment (chemical risks, microbial risks, and national reporting on food consumption), risk management (national food safety capacities, food recalls, food traceability, and radionuclides standards), and risk communication (allergenic risks, labeling, and public trust). Results show all countries have very high food safety standards, but Canada and Ireland, followed by France, earned excellent grades relative to their peers. However, any subsequent global ranking study should consider the development of survey instruments to gather adequate and comparable national evidence on food safety.

  1. Facility effluent monitoring plan for the tank farms facilities

    Energy Technology Data Exchange (ETDEWEB)

    Bachand, D.D.; Crummel, G.M.

    1995-05-01

    A facility effluent monitoring plan is required by the US Department of Energy for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This document is prepared using specific guidelines. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. This facility effluent monitoring plan shall ensure long-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated as a minimum every three years.

  2. Mine-shaft conveyance monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Beus, M.J.; Ruff, T.M.; Iverson, S.; McCoy, W.G. [National Institute for Occupational Safety and Health, Spokane, WA (USA). Spokane Research Laboratory

    2000-10-01

    Monitoring conveyance position and wire rope load directly from the skip or cage top offers several significant safety and production advantages. The Spokane Research Laboratory (SRL) of the National Institute for Occupational Safety and Health (NIOSH) developed a shaft conveyance monitoring system (SCMS). This system consists of position and guide-displacement sensors, a maintenance-free battery power supply and a new sensor, which is mounted on the wire rope with a Crosby Clip, to measure hoist-rope tension. A radio data link transmits sensor output to the hoist room. A state-of-the-art automated hoisting test facility was also constructed to test the concept in a controlled laboratory setting. Field tests are now underway at the SRL hoisting research facility and in deep mine shafts in northern Idaho. 4 refs., 5 figs.

  3. Radiation safety of Takasaki ion accelerators for advanced radiation in JAERI

    International Nuclear Information System (INIS)

    Watanabe, Hiromasa; Tanaka, Susumu; Anazawa, Yutaka

    1991-01-01

    Building layout of Takasaki ion accelerator facility has been started since 1987, with the propulsion of research development of (1) cosmetic environment materials, (2) nuclear fusion reactors, (3) biotechnology, and (4) new functional materials. This paper deals with an AVF cyclotron and a tandem type accelerator, focusing on safety design, radiation safety management, and radioactive waste management. Safety design is discussed in view of radiation shielding and activation countermeasures. Radiation safety management covers radiation monitoring in the workplace, exhaust radioactivity, environment outside the facility, and the other equipments; personal monitoring; and protective management of exposure. For radiation waste management, basic concept and management methods are commented on. (N.K.)

  4. Regulatory regime and its influence in the nuclear safety

    International Nuclear Information System (INIS)

    Laaksonen, J.

    1999-01-01

    Main elements of nuclear regulatory regime in general is presented. These elements are: national rules and safety regulations, system of nuclear facility licensing, activities of regulatory body. Regulatory body is needed to specify the national safety regulations, review and assess the safety documentation presented to support license application, make inspections to verify fulfilment of safety regulations and license conditions, monitor the quality of work processes of user organization, and to assess whether these processes provide a high safety level, promote high safety culture, promote maintenance and development of national infrastructure relevant to nuclear safety, etc

  5. KHNP Safety Culture Framework based on Global Standard, and Lessons learned from Safety Culture Evaluation

    International Nuclear Information System (INIS)

    Kim, Younggab; Hur, Nam Young; Jeong, Hyeon Jong

    2015-01-01

    In order to eliminate the vague fears of the people about the nuclear power and operate continuously NPPs, a strong safety culture of NPPs should be demonstrated. Strong safety culture awareness of workers can overcome social distrust about NPPs. KHNP has been a variety efforts to improve and establish safety culture of NPPs. Safety culture framework applying global standards was set up and safety culture assessment has been carried out periodically to enhance safety culture of workers. In addition, KHNP developed various safety culture contents and they are being used in NPPs by workers. As a result of these efforts, safety culture awareness of workers is changed positively and the safety environment of NPPs is expected to be improved. KHNP makes an effort to solve areas for improvement derived from safety culture assessment. However, there are some areas to take a long time in completing the work. Therefore, these actions are necessary to be carried out consistently and continuously. KHNP also developed recently safety culture enhancement system based on web. All information related to safety culture in KHNP will be shared through this web system and this system will be used to safety culture assessment. In addition to, KHNP plans to develop safety culture indicators for monitoring the symptoms of safety culture weakening

  6. KHNP Safety Culture Framework based on Global Standard, and Lessons learned from Safety Culture Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Younggab; Hur, Nam Young; Jeong, Hyeon Jong [KHNP Central Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    In order to eliminate the vague fears of the people about the nuclear power and operate continuously NPPs, a strong safety culture of NPPs should be demonstrated. Strong safety culture awareness of workers can overcome social distrust about NPPs. KHNP has been a variety efforts to improve and establish safety culture of NPPs. Safety culture framework applying global standards was set up and safety culture assessment has been carried out periodically to enhance safety culture of workers. In addition, KHNP developed various safety culture contents and they are being used in NPPs by workers. As a result of these efforts, safety culture awareness of workers is changed positively and the safety environment of NPPs is expected to be improved. KHNP makes an effort to solve areas for improvement derived from safety culture assessment. However, there are some areas to take a long time in completing the work. Therefore, these actions are necessary to be carried out consistently and continuously. KHNP also developed recently safety culture enhancement system based on web. All information related to safety culture in KHNP will be shared through this web system and this system will be used to safety culture assessment. In addition to, KHNP plans to develop safety culture indicators for monitoring the symptoms of safety culture weakening.

  7. Post-accident monitoring systems in Prototype Fast Breeder Reactor

    International Nuclear Information System (INIS)

    Suriya Murthy, N.; Sivasailanathan, Vidhya; Ananth, Allu; Roy, Kallol

    2018-01-01

    PFBR is a 500 MW(e) MOX fueled and sodium cooled fast reactor (SFR) under advanced stage of commissioning at Kalpakkam. Currently, the main vessel is preheated and sodium has been charged into two secondary loops that are operated in recirculation mode. In order to characterize the radiation field and contamination, the workplace monitoring is undertaken using installed monitors that are commissioned and made operational. This helps to ensure radiological protection during normal operating conditions. On the other hand, radiological monitoring in emergency conditions is quite different. For undertaking the mitigative accident management, a set of specialized nuclear instruments called post-accident monitoring systems (PAMS) which include radiation monitors are stipulated. The Fukushima Daiichi accident emphasized the importance and need for reliable accident monitoring instrumentation to indicate the safety functions during the progression and aftermath of accident in NPP. In PFBR, the PAMS are integrated with other monitoring systems in design stage itself to manage the measurements and indicating the safety functions for implementing EOP and SAMG

  8. Real-time beam monitoring in scanned proton therapy

    Science.gov (United States)

    Klimpki, G.; Eichin, M.; Bula, C.; Rechsteiner, U.; Psoroulas, S.; Weber, D. C.; Lomax, A.; Meer, D.

    2018-05-01

    When treating cancerous tissues with protons beams, many centers make use of a step-and-shoot irradiation technique, in which the beam is steered to discrete grid points in the tumor volume. For safety reasons, the irradiation is supervised by an independent monitoring system validating cyclically that the correct amount of protons has been delivered to the correct position in the patient. Whenever unacceptable inaccuracies are detected, the irradiation can be interrupted to reinforce a high degree of radiation protection. At the Paul Scherrer Institute, we plan to irradiate tumors continuously. By giving up the idea of discrete grid points, we aim to be faster and more flexible in the irradiation. But the increase in speed and dynamics necessitates a highly responsive monitoring system to guarantee the same level of patient safety as for conventional step-and-shoot irradiations. Hence, we developed and implemented real-time monitoring of the proton beam current and position. As such, we read out diagnostic devices with 100 kHz and compare their signals against safety tolerances in an FPGA. In this paper, we report on necessary software and firmware enhancements of our control system and test their functionality based on three exemplary error scenarios. We demonstrate successful implementation of real-time beam monitoring and, consequently, compliance with international patient safety regulations.

  9. Using ATP-driven bioluminescence assay to monitor microbial safety in a contemporary human cadaver laboratory.

    Science.gov (United States)

    Benninger, Brion; Maier, Thomas

    2015-03-01

    The objective of this study was to utilize a cost-effective method for assessing the levels of bacterial, yeast, and mold activity during a human dissection laboratory course. Nowadays, compliance with safety regulations is policed by institutions at higher standards than ever before. Fear of acquiring an unknown infection is one of the top concerns of professional healthcare students, and it provokes anti-laboratory anxiety. Human cadavers are not routinely tested for bacteria and viruses prior to embalming. Human anatomy dissecting rooms that house embalmed cadavers are normally cleaned after the dissected cadavers have been removed. There is no evidence that investigators have ever assessed bacterial and fungal activities using adenosine triphosphate (ATP)-driven bioluminescence assays. A literature search was conducted on texts, journals, and websites regarding bacterial, yeast, and mold activities in an active cadaver laboratory. Midway into a clinical anatomy course, ATP bioluminescence assays were used to swab various sites within the dissection room, including entrance and exiting door handles, water taps, cadaver tables, counter tops, imaging material, X-ray box switches, and the cadaver surfaces. The results demonstrated very low activities on cadaver tables, washing up areas, and exiting door handles. There was low activity on counter tops and X-ray boxes. There was medium activity on the entrance door handles. These findings suggest an inexpensive and accurate method for monitoring safety compliance and microbial activity. Students can feel confident and safe in the environment in which they work. © 2014 Wiley Periodicals, Inc.

  10. A radiation monitoring system for nuclear power plants

    International Nuclear Information System (INIS)

    Iwai, Masaru; Nakamori, S.; Ikeda, H.; Oda, M.

    1974-01-01

    Safety with respect to radiation is vital factor, particularly in view of the increasing number of nuclear power plants. For this purpose, a radiation monitoring system is provided to perform constant supervision. This article describes the purpose, installation location, specifications and circuitry of a system which is divided into three units: the process monitor, area monitor and off-site monitor. (auth.)

  11. 30 CFR 56.5002 - Exposure monitoring.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Exposure monitoring. 56.5002 Section 56.5002 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Agents Air Quality § 56.5002 Exposure monitoring. Dust, gas, mist, and fume surveys shall be conducted as...

  12. Tools and techniques for ageing predictions in nuclear reactors through condition monitoring

    International Nuclear Information System (INIS)

    Verma, R.M.P.

    1994-01-01

    To operate the nuclear reactors beyond their design predicted life is gaining importance because of huge replacement and decommissioning costs. But experience shows that nuclear plant safety and reliability may decline in the later years of plant life due to ageing degradation. Ageing of nuclear plant components, structures and systems, if unmitigated reduces their safety margins provided in the design and thus increases risks to public health and safety. These safety margins must be monitored throughout plant service life including any extended life. Condition monitoring of nuclear reactor components/equipment and systems can be done to study the effect of ageing, status of safety margins and effect of corrective and mitigating actions taken. The tools and techniques of condition monitoring are also important in failure trending, predictive maintenance, evaluation of scheduled maintenance, in mitigation of ageing, life extension and reliability studies. (author). 1 fig., 1 annexure

  13. Preliminary Integrated Safety Analysis Status Report

    International Nuclear Information System (INIS)

    Gwyn, D.

    2001-01-01

    This report provides the status of the potential Monitored Geologic Repository (MGR) Integrated Safety Analysis (EA) by identifying the initial work scope scheduled for completion during the ISA development period, the schedules associated with the tasks identified, safety analysis issues encountered, and a summary of accomplishments during the reporting period. This status covers the period from October 1, 2000 through March 30, 2001

  14. Facility Effluent Monitoring Plan for the uranium trioxide facility

    International Nuclear Information System (INIS)

    Lohrasbi, J.; Johnson, D.L.; De Lorenzo, D.S.

    1993-12-01

    A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438-01. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. This facility effluent monitoring plan shall ensure long-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated at a minimum of every three years

  15. The Use of Wireless Sensor Network for Increasing Airport Safety

    Directory of Open Access Journals (Sweden)

    Jakub Kraus

    2013-09-01

    Full Text Available This article deals with the use of wireless sensor networks for increasing safety at airports, respectively for replacing the current monitoring system to ensure safety. The article describes sensor networks and their applications to the identified processes and consideration of financial and safety benefits.

  16. Perspectives on radioactive waste repository monitoring. Confirmation, compliance, confidence building, and societal vigilance

    Energy Technology Data Exchange (ETDEWEB)

    Bergmans, Anne [Antwerp Univ. (Belgium). Research Group Society and Environment; Elam, Mark [Gothenburg Univ. (Sweden); Simmons, Peter [East Anglia Univ., Norwich (United Kingdom); Sundqvist, Goeran [Oslo Univ. (Norway)

    2012-12-15

    Monitoring is now widely seen as a necessary part of programmes for the geological disposal of radioactive waste. However, we find different perspectives on the nature and role of monitoring. Among technical experts it is viewed firstly as a matter of performance confirmation, a tool for validating the safety case underlying repository construction. Among concerned citizens we find a view of monitoring as enabling the critical scrutiny of safety, an instrument for acknowledging uncertainties and detecting emergent problems in a repository. After outlining differing views on questions of whether, why, what, where and for how long to monitor we discuss monitoring in light of constant vigilance as a technical and moral principle of nuclear safety. We suggest that ''how much monitoring'' and ''how should it be organised'' are societal questions and as such need to be broadly discussed.

  17. A modular, prospective, semi-automated drug safety monitoring system for use in a distributed data environment.

    Science.gov (United States)

    Gagne, Joshua J; Wang, Shirley V; Rassen, Jeremy A; Schneeweiss, Sebastian

    2014-06-01

    The aim of this study was to develop and test a semi-automated process for conducting routine active safety monitoring for new drugs in a network of electronic healthcare databases. We built a modular program that semi-automatically performs cohort identification, confounding adjustment, diagnostic checks, aggregation and effect estimation across multiple databases, and application of a sequential alerting algorithm. During beta-testing, we applied the system to five databases to evaluate nine examples emulating prospective monitoring with retrospective data (five pairs for which we expected signals, two negative controls, and two examples for which it was uncertain whether a signal would be expected): cerivastatin versus atorvastatin and rhabdomyolysis; paroxetine versus tricyclic antidepressants and gastrointestinal bleed; lisinopril versus angiotensin receptor blockers and angioedema; ciprofloxacin versus macrolide antibiotics and Achilles tendon rupture; rofecoxib versus non-selective non-steroidal anti-inflammatory drugs (ns-NSAIDs) and myocardial infarction; telithromycin versus azithromycin and hepatotoxicity; rosuvastatin versus atorvastatin and diabetes and rhabdomyolysis; and celecoxib versus ns-NSAIDs and myocardial infarction. We describe the program, the necessary inputs, and the assumed data environment. In beta-testing, the system generated four alerts, all among positive control examples (i.e., lisinopril and angioedema; rofecoxib and myocardial infarction; ciprofloxacin and tendon rupture; and cerivastatin and rhabdomyolysis). Sequential effect estimates for each example were consistent in direction and magnitude with existing literature. Beta-testing across nine drug-outcome examples demonstrated the feasibility of the proposed semi-automated prospective monitoring approach. In retrospective assessments, the system identified an increased risk of myocardial infarction with rofecoxib and an increased risk of rhabdomyolysis with cerivastatin years

  18. Facility effluent monitoring plan for the 284-E and 284-W power plants

    International Nuclear Information System (INIS)

    Nickels, J.M.; Herman, D.R.

    1992-11-01

    A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. A facility effluent monitoring plan determination was performed during calendar year 1991 and the evaluation requires the need for a facility effluent monitoring plan. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements

  19. Safety class methodology

    International Nuclear Information System (INIS)

    Donner, E.B.; Low, J.M.; Lux, C.R.

    1992-01-01

    DOE Order 6430.1A, General Design Criteria (GDC), requires that DOE facilities be evaluated with respect to ''safety class items.'' Although the GDC defines safety class items, it does not provide a methodology for selecting safety class items. The methodology described in this paper was developed to assure that Safety Class Items at the Savannah River Site (SRS) are selected in a consistent and technically defensible manner. Safety class items are those in the highest of four categories determined to be of special importance to nuclear safety and, merit appropriately higher-quality design, fabrication, and industrial test standards and codes. The identification of safety class items is approached using a cascading strategy that begins at the 'safety function' level (i.e., a cooling function, ventilation function, etc.) and proceeds down to the system, component, or structure level. Thus, the items that are required to support a safety function are SCls. The basic steps in this procedure apply to the determination of SCls for both new project activities, and for operating facilities. The GDC lists six characteristics of SCls to be considered as a starting point for safety item classification. They are as follows: 1. Those items whose failure would produce exposure consequences that would exceed the guidelines in Section 1300-1.4, ''Guidance on Limiting Exposure of the Public,'' at the site boundary or nearest point of public access 2. Those items required to maintain operating parameters within the safety limits specified in the Operational Safety Requirements during normal operations and anticipated operational occurrences. 3. Those items required for nuclear criticality safety. 4. Those items required to monitor the release of radioactive material to the environment during and after a Design Basis Accident. Those items required to achieve, and maintain the facility in a safe shutdown condition 6. Those items that control Safety Class Item listed above

  20. Practicing industrial safety - issues involved

    International Nuclear Information System (INIS)

    Gunasekaran, P.

    2016-01-01

    Industrial safety is all about measures or techniques implemented to reduce the risk of injury, loss to persons, property or the environment in any industrial facility. The issue of industrial safety evolved concurrently with industrial development as a shift from compensation to prevention as well. Today, industrial safety is widely regarded as one of the most important factors that any business, large or small, must consider in its operations, as prevention of loss is also a part of profit. Factories Act of Central government and Rules made under it by the state deals with the provisions on industrial safety legislation. There are many other acts related to safety of personnel, property and environment. Occupational health and safety is also of primary concern. The aim is to regulate health and safety conditions for all employers. It includes safety standards and health standards. These acts encourage employers and employees to reduce workplace hazards and to implement new or improve existing safety and health standards; and develop innovative ways to achieve them. Maintain a reporting and record keeping system to monitor job-related injuries and illnesses; establish training programs to increase the number and competence of occupational safety and health personnel

  1. Safety aspects of neutron noise diagnostics and loose parts monitoring in WWER reactors

    International Nuclear Information System (INIS)

    Por, G.

    1997-01-01

    In this paper our aim is to give very short introduction on different types of well selected noise diagnostics methods and then mentioning their occurrence in WWER reactors we analyze what impact they might have to operational safety and for ageing (which also affects on safety of the installations). We do not deny, that one of our main aim is to call the attention of management staff of NPP, which deals with safety, safety culture, maintenance and operation proving, that such methods and system can give not only benefit to economy but also impact on safety of nuclear installations. 14 refs, 6 figs

  2. Facility effluent monitoring plan for 242-A evaporator facility

    International Nuclear Information System (INIS)

    Crummel, G.M.; Gustavson, R.D.

    1995-02-01

    A facility effluent monitoring plan is required by the U.S. Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could affect employee or public safety or the environment. A facility effluent monitoring plan determination was performed during Calendar Year 1991 and the evaluation showed the need for a facility effluent monitoring plan. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438-1. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. This facility effluent monitoring plan shall ensure long-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated, as a minimum, every three years

  3. Application of the statistical process control method for prospective patient safety monitoring during the learning phase: robotic kidney transplantation with regional hypothermia (IDEAL phase 2a-b).

    Science.gov (United States)

    Sood, Akshay; Ghani, Khurshid R; Ahlawat, Rajesh; Modi, Pranjal; Abaza, Ronney; Jeong, Wooju; Sammon, Jesse D; Diaz, Mireya; Kher, Vijay; Menon, Mani; Bhandari, Mahendra

    2014-08-01

    Traditional evaluation of the learning curve (LC) of an operation has been retrospective. Furthermore, LC analysis does not permit patient safety monitoring. To prospectively monitor patient safety during the learning phase of robotic kidney transplantation (RKT) and determine when it could be considered learned using the techniques of statistical process control (SPC). From January through May 2013, 41 patients with end-stage renal disease underwent RKT with regional hypothermia at one of two tertiary referral centers adopting RKT. Transplant recipients were classified into three groups based on the robotic training and kidney transplant experience of the surgeons: group 1, robot trained with limited kidney transplant experience (n=7); group 2, robot trained and kidney transplant experienced (n=20); and group 3, kidney transplant experienced with limited robot training (n=14). We employed prospective monitoring using SPC techniques, including cumulative summation (CUSUM) and Shewhart control charts, to perform LC analysis and patient safety monitoring, respectively. Outcomes assessed included post-transplant graft function and measures of surgical process (anastomotic and ischemic times). CUSUM and Shewhart control charts are time trend analytic techniques that allow comparative assessment of outcomes following a new intervention (RKT) relative to those achieved with established techniques (open kidney transplant; target value) in a prospective fashion. CUSUM analysis revealed an initial learning phase for group 3, whereas groups 1 and 2 had no to minimal learning time. The learning phase for group 3 varied depending on the parameter assessed. Shewhart control charts demonstrated no compromise in functional outcomes for groups 1 and 2. Graft function was compromised in one patient in group 3 (pcontrol chart analytic techniques. These methods allow determination of the duration of mentorship and identification of adverse events in a timely manner. A new operation

  4. Nuclear health and safety

    International Nuclear Information System (INIS)

    1990-04-01

    This report summarizes the responsiveness of DOE and contractors to findings contained in DOE technical safety appraisals and environmental surveys. These appraisals and surveys have been done at DOE facilities and sites to find out the extent of the environmental, safety, and health problems and to prioritize them for corrective action. As of January 1990, DOE computer data showed over 1,700 safety and health problems and almost 1,300 environmental problems. The majority of these problems, however, have not yet been corrected. GAO also looked at the extent to which DOE has developed a computerized tracking system to monitor the status of its environmental, safety, and health problems. GAO found that the computer system lacks important information, such as various field office and independent appraisals. Inclusion of this information would provide a more complete picture of the problems at the site

  5. A study on the condition monitoring for safety-related electric cables

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chul Hwan; Ahn, S. P.; Yeo, S. M.; Kang, Y. S.; Ahn, S. M.; Kim, I. S.; Kim, D. S.; Kang, J. S. [Sungkyunkwan Univ., Suwon (Korea, Republic of)

    2002-03-15

    In this report, we have studied compositions and characteristics of various types of insulation material for cables in Nuclear Power Plant. We arrange relationship with condition monitoring methods. Also, we propose new condition monitoring method using third harmonic frequency. We test the proposed method with CV cables. We also describe about feature of condition monitoring such as application, theory, characteristic, thereby other engineer can confirm to advantage and disadvantage for each method, and possibly choice adequate condition monitoring method for various types of cables.

  6. Prospective drug safety monitoring using the UK primary-care General Practice Research Database: theoretical framework, feasibility analysis and extrapolation to future scenarios.

    Science.gov (United States)

    Johansson, Saga; Wallander, Mari-Ann; de Abajo, Francisco J; García Rodríguez, Luis Alberto

    2010-03-01

    Post-launch drug safety monitoring is essential for the detection of adverse drug signals that may be missed during preclinical trials. Traditional methods of postmarketing surveillance such as spontaneous reporting have intrinsic limitations, many of which can be overcome by the additional application of structured pharmacoepidemiological approaches. However, further improvement in drug safety monitoring requires a shift towards more proactive pharmacoepidemiological methods that can detect adverse drug signals as they occur in the population. To assess the feasibility of using proactive monitoring of an electronic medical record system, in combination with an independent endpoint adjudication committee, to detect adverse events among users of selected drugs. UK General Practice Research Database (GPRD) information was used to detect acute liver disorder associated with the use of amoxicillin/clavulanic acid (hepatotoxic) or low-dose aspirin (acetylsalicylic acid [non-hepatotoxic]). Individuals newly prescribed these drugs between 1 October 2005 and 31 March 2006 were identified. Acute liver disorder cases were assessed using GPRD computer records in combination with case validation by an independent endpoint adjudication committee. Signal generation thresholds were based on the background rate of acute liver disorder in the general population. Over a 6-month period, 8148 patients newly prescribed amoxicillin/clavulanic acid and 5577 patients newly prescribed low-dose aspirin were identified. Within this cohort, searches identified 11 potential liver disorder cases from computerized records: six for amoxicillin/clavulanic acid and five for low-dose aspirin. The independent endpoint adjudication committee refined this to four potential acute liver disorder cases for whom paper-based information was requested for final case assessment. Final case assessments confirmed no cases of acute liver disorder. The time taken for this study was 18 months (6 months for

  7. Medicine safety and children

    Science.gov (United States)

    ... it is candy. What to Do If Your Child Takes Medicine If you think your child has taken medicine, call the poison control center ... blood pressure monitored. Preventing Medicine Mistakes When giving medicine to your young child, follow these safety tips: Use medicine made only ...

  8. Facility effluent monitoring plan for the 2724-W Protective Equipment Decontamination Facility

    International Nuclear Information System (INIS)

    Nickels, J.M.; Lavey, G.H.

    1992-12-01

    A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1* for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. A facility effluent monitoring plan determination was performed during Calendar Year 1991 and the evaluation requires the need for a facility effluent monitoring plan. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438**. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements

  9. Safety basis for the 241-AN-107 mixer pump installation and caustic addition

    International Nuclear Information System (INIS)

    Van Vleet, R.J.

    1994-01-01

    This safety Basis was prepared to determine whether or not the proposed activities of installing a 76 HP jet mixer pump and the addition of approximately 50,000 gallons of 19 M (50:50 wt %) aqueous caustic are within the safety envelope as described by Tank Farms (chapter six of WHC-SD-WM-ISB-001, Rev. 0). The safety basis covers the components, structures and systems for the caustic addition and mixer pump installation. These include: installation of the mixer pump and monitoring equipment; operation of the mixer pump, process monitoring equipment and caustic addition; the pump stand, caustic addition skid, the electrical skid, the video camera system and the two densitometers. Also covered is the removal and decontamination of the mixer pump and process monitoring system. Authority for this safety basis is WHC-IP-0842 (Waste Tank Administration). Section 15.9, Rev. 2 (Unreviewed Safety Questions) of WHC-IP-0842 requires that an evaluation be performed for all physical modifications

  10. Computer monitoring of the RB reactor operation

    International Nuclear Information System (INIS)

    Milovanovic, S.; Pesic, M.; Milovanovic, T.

    1998-01-01

    Personal computer based acquisition system designed for monitoring of operation of the RB experimental reactor in the Institute of Nuclear Sciences 'Vinca' (former 'Boris Kidric') and experiences acquired during its use are shown in this paper. The monitoring covers generally all nuclear aspects of the reactor operation (start-up, nominal power operation, power changing, shut down and maintenance), but the emphasis is put on: real time (especially fast changing) reactivity measurement; supervising time dependence of the safety rods positions during shut down, and detection of position inaccuracy or failure operation of safety/control rods during the reactor operation or maintenance. (author)

  11. Augmented reality for improved safety

    CERN Multimedia

    Stefania Pandolfi

    2016-01-01

    Sometimes, CERN experts have to operate in low visibility conditions or in the presence of possible hazards. Minimising the duration of the operation and reducing the risk of errors is therefore crucial to ensuring the safety of personnel. The EDUSAFE project integrates different technologies to create a wearable personnel safety system based on augmented reality.    The EDUSAFE integrated safety system uses a camera mounted on the helmet to monitor the working area.  In its everyday operation of machines and facilities, CERN adopts a whole set of measures and safety equipment to ensure the safety of its personnel, including personal wearable safety devices and access control systems. However, sometimes, scheduled and emergency maintenance work needs to be done in zones with potential cryogenic hazards, in the presence of radioactive equipment or simply in demanding conditions where visibility is low and moving around is difficult. The EDUSAFE Marie Curie Innovative&...

  12. The development of web monitoring digital area monitor

    International Nuclear Information System (INIS)

    Jung, Hoon-Jin; Lee, Jun-Hee; Namkoong, Phil; Lee, Dong-Hoon; Lee, Su-Hong; Kim, We-Su

    2005-01-01

    As CCTV and radiation area monitor have been used separately to date, there have existed inconveniences in managing the view images and radiation dose rates from them. Thus we became to develop the web monitoring digital area monitor which incorporated the existing two factors, CCTV and radiation area monitor, into one. As incorporated with digitalisation, this device will usually become linked with PC, so that the view image and radiation dose rate can be concurrently identified in convenience. These measured figures automatically become data-based on PC by SW program, and become displayed in various format. Moreover, they can be monitored in remote and real time basis in the internet environment. Its local unit uses the cost-effective GM tube and CMOS image sensor, and has the small LCD which directly indicates the measured dose rate. The image sensor is designed to be operated with pan and tilt motion, thus can eliminate the dead view zone. It is thought that the developed device at this time could make the radiation safety management of each work field be done with low cost-high efficiency manner, making role of the CCTV inspection system

  13. The development of web monitoring digital area monitor

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Hoon-Jin; Lee, Jun-Hee; Namkoong, Phil; Lee, Dong-Hoon; Lee, Su-Hong; Kim, We-Su [Iljin Radiation Engineering Co., Seoul (Korea, Republic of)

    2005-11-15

    As CCTV and radiation area monitor have been used separately to date, there have existed inconveniences in managing the view images and radiation dose rates from them. Thus we became to develop the web monitoring digital area monitor which incorporated the existing two factors, CCTV and radiation area monitor, into one. As incorporated with digitalisation, this device will usually become linked with PC, so that the view image and radiation dose rate can be concurrently identified in convenience. These measured figures automatically become data-based on PC by SW program, and become displayed in various format. Moreover, they can be monitored in remote and real time basis in the internet environment. Its local unit uses the cost-effective GM tube and CMOS image sensor, and has the small LCD which directly indicates the measured dose rate. The image sensor is designed to be operated with pan and tilt motion, thus can eliminate the dead view zone. It is thought that the developed device at this time could make the radiation safety management of each work field be done with low cost-high efficiency manner, making role of the CCTV inspection system.

  14. Study on the Problems and Countermeasure in the Animal Products Quality and Safety

    Institute of Scientific and Technical Information of China (English)

    Shishan; WANG

    2013-01-01

    As the supply chain of animal products is long,there are many factors which would influence the quality safety of animal production.Therefore,by focusing on the present and having a vision for future,Jiaozuo government promulgated Ten Polices on the Food Safety in Jiaozuo City,which pushed forward the technological development,intensified measures to monitor the quality of animal products,set up a series of mechanism,and provided reference for the food quality and safety monitoring.

  15. Nordic studies in reactor safety

    International Nuclear Information System (INIS)

    Pershagen, N.

    1993-01-01

    The Nordic Nuclear Safety Research Programme SIK programme in reactor safety is part of a major joint Nordic research effort in nuclear safety. The report summarizes the achievements of the SIK programme, which was carried out during 1990-1993 in collaboration between Nordic nuclear utilities, safety authorities, and research institutes. Three main projects were successfully completed dealing with: 1) development and application of a living PSA concept for monitoring the risk of core damage, and of safety indicators for early warning of possible safety problems; 2) review and intercomparison of severe accident codes, case studies of potential core melt accidents in nordic reactors, development of chemical models for the MAAP code, and outline of a system for computerized accident management support; 3) compilation of information about design and safety features of neighbouring reactors in Germany, Lithuania and Russia, and for naval reactors and nuclear submarines. The report reviews the state-of-the-art in each subject matter as an introduction to the individual project summaries. The main findings of each project are highlighted. The report also contains an overview of reactor safety research in the Nordic countries and a summary of fundamental reactor safety principles. (au) (69 refs.)

  16. Quality assurance for software important to safety

    International Nuclear Information System (INIS)

    2000-01-01

    Software applications play an increasingly relevant role in nuclear power plant systems. This is particularly true of software important to safety used in both: calculations for the design, testing and analysis of nuclear reactor systems (design, engineering and analysis software); and monitoring, control and safety functions as an integral part of the reactor systems (monitoring, control and safety system software). Computer technology is advancing at a fast pace, offering new possibilities in nuclear reactor design, construction, commissioning, operation, maintenance and decommissioning. These advances also present new issues which must be considered both by the utility and by the regulatory organization. Refurbishment of ageing instrumentation and control systems in nuclear power plants and new safety related application areas have emerged, with direct (e.g. interfaces with safety systems) and indirect (e.g. operator intervention) implications for safety. Currently, there exist several international standards and guides on quality assurance for software important to safety. However, none of the existing documents provides comprehensive guidance to the developer, manager and regulator during all phases of the software life-cycle. The present publication was developed taking into account the large amount of available documentation, the rapid development of software systems and the need for updated guidance on h ow to do it . It provides information and guidance for defining and implementing quality assurance programmes covering the entire life-cycle of software important to safety. Expected users are managers, performers and assessors from nuclear utilities, regulatory bodies, suppliers and technical support organizations involved with the development and use of software applied in nuclear power plants

  17. Reactor operation safety information document

    Energy Technology Data Exchange (ETDEWEB)

    1990-01-01

    The report contains a reactor facility description which includes K, P, and L reactor sites, structures, operating systems, engineered safety systems, support systems, and process and effluent monitoring systems; an accident analysis section which includes cooling system anomalies, radioactive materials releases, and anticipated transients without scram; a summary of onsite doses from design basis accidents; severe accident analysis (reactor core disruption); a description of operating contractor organization and emergency planning; and a summary of reactor safety evolution. (MB)

  18. Aviation Safety Simulation Model

    Science.gov (United States)

    Houser, Scott; Yackovetsky, Robert (Technical Monitor)

    2001-01-01

    The Aviation Safety Simulation Model is a software tool that enables users to configure a terrain, a flight path, and an aircraft and simulate the aircraft's flight along the path. The simulation monitors the aircraft's proximity to terrain obstructions, and reports when the aircraft violates accepted minimum distances from an obstruction. This model design facilitates future enhancements to address other flight safety issues, particularly air and runway traffic scenarios. This report shows the user how to build a simulation scenario and run it. It also explains the model's output.

  19. Distributed optical fiber sensors for integrated monitoring of railway infrastructures

    Science.gov (United States)

    Minardo, Aldo; Coscetta, Agnese; Porcaro, Giuseppe; Giannetta, Daniele; Bernini, Romeo; Zeni, Luigi

    2014-05-01

    We propose the application of a distributed optical fiber sensor based on stimulated Brillouin scattering, as an integrated system for safety monitoring of railway infrastructures. The strain distribution was measured dynamically along a 60 meters length of rail track, as well as along a 3-m stone arch bridge. The results indicate that distributed sensing technology is able to provide useful information in railway traffic and safety monitoring.

  20. Design and implementation of an integrated safety management system for compressed natural gas stations using ubiquitous sensor network

    International Nuclear Information System (INIS)

    Yang, Jae Mo; Ko, Byung Seok; Park, Chulhwan; Ko, Jae Wook; Yoo, Byungtae; Shin, Dongil

    2014-01-01

    To increase awareness of safety in facilities where hazards may exist, operators, managers, and executive officers on the site should be able to monitor such facilities. However, most compressed natural gas (CNG) service stations in Korea use only local-mode monitoring, with only on-site operators to monitor the facility. To complement this local-mode monitoring, an online safety management system called Ubiquitous-gas safety management system (U-GSMS) was developed. The U-GSMS consists largely of software and hardware. The software consists of systems that can manage safety and operations, while the hardware consists of sensors installed in the gas facility and wireless communication systems using a ubiquitous sensor network (USN) technology that facilitates communication between sensors as well as between sensors and other devices. As these systems are web-based, on-site operators as well as managers and executive officers at the headquarters can more effectively and efficiently perform monitoring and safety management

  1. Design and implementation of an integrated safety management system for compressed natural gas stations using ubiquitous sensor network

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Jae Mo; Ko, Byung Seok; Park, Chulhwan; Ko, Jae Wook [Kwangwoon University, Seoul (Korea, Republic of); Yoo, Byungtae [National Disaster Management Institute, Seoul (Korea, Republic of); Shin, Dongil [Myongji University, Yongin (Korea, Republic of)

    2014-03-15

    To increase awareness of safety in facilities where hazards may exist, operators, managers, and executive officers on the site should be able to monitor such facilities. However, most compressed natural gas (CNG) service stations in Korea use only local-mode monitoring, with only on-site operators to monitor the facility. To complement this local-mode monitoring, an online safety management system called Ubiquitous-gas safety management system (U-GSMS) was developed. The U-GSMS consists largely of software and hardware. The software consists of systems that can manage safety and operations, while the hardware consists of sensors installed in the gas facility and wireless communication systems using a ubiquitous sensor network (USN) technology that facilitates communication between sensors as well as between sensors and other devices. As these systems are web-based, on-site operators as well as managers and executive officers at the headquarters can more effectively and efficiently perform monitoring and safety management.

  2. Operations report 1985 of the Department of Safety and Radiation Protection

    International Nuclear Information System (INIS)

    Hille, R.; Frenkler, K.L.

    1986-04-01

    Under the heading 'Licensing' the report deals with licensing procedures and the handling of nuclear-fuels and radioactive materials. Operational radiation protection is concerned with operational and personnel monitoring, mathematical methods and safety analyses. Environmental protection deals with emission control, immission monitoring and meteorological measurements, and safety technology with α/β-analysis, dosimetry, equipment servicing and mechanics, nuclear material safeguards. Other subdepartments take care of industrial safety, physical protection, emergency protection and training. Subjects dealt with, too, are dispersion pollutants in atmosphere and environment, further development of radiation protection methods, and the bibliography of radiation protection in KFA. (HK) [de

  3. Maintenance of radiation monitoring systems

    International Nuclear Information System (INIS)

    Aoyama, Kei

    2001-01-01

    As the safety and quality of atomic power facilities are more strongly required, the reliability improvement and preventive maintenance of radiation monitoring systems are important. This paper describes the maintenance of radiation monitoring systems delivered by Fuji Electric and the present status of preventive maintenance technology. Also it introduces the case that we developed a fault diagnosis function adopting a statistics technique and artificial intelligence (AI) and delivered a radiation monitoring system including this function. This system can output a fault analysis result and a countermeasure from the computer in real time. (author)

  4. Monitoring human factor risk characteristics at nuclear legacy sites in northwest Russia in support of radiation safety regulation.

    Science.gov (United States)

    Scheblanov, V Y; Sneve, M K; Bobrov, A F

    2012-12-01

    This paper describes research aimed at improving regulatory supervision of radiation safety during work associated with the management of spent nuclear fuel and radioactive waste at legacy sites in northwest Russia through timely identification of employees presenting unfavourable human factor risk characteristics. The legacy sites of interest include sites of temporary storage now operated by SevRAO on behalf of Rosatom. The sites were previously operational bases for servicing nuclear powered submarines and are now subject to major remediation activities. These activities include hazardous operations for recovery of spent nuclear fuel and radioactive waste from sub-optimal storage conditions. The paper describes the results of analysis of methods, procedures, techniques and informational issues leading to the development of an expert-diagnostic information system for monitoring of workers involved in carrying out the most hazardous operations. The system serves as a tool for human factor and professional reliability risk monitoring and has been tested in practical working environments and implemented as part of regulatory supervision. The work has been carried out by the Burnasyan Federal Medical Biophysical Center, within the framework of the regulatory cooperation programme between the Federal Medical-Biological Agency of Russia and the Norwegian Radiation Protection Authority.

  5. Design of position monitor module in radioactive material transport monitoring system

    International Nuclear Information System (INIS)

    Adi Abimanyu; Dwi Yuliansari N

    2013-01-01

    Aspects of safety and security of radioactive substances from the sender to the receiver is to be secured so as not to harm humans. In general, monitoring is done through conversation by telephone to determine the location and rate of exposure of radioactive substances. Through the development of science and technology makes it possible to develop a system of monitoring the transport of radioactive substances in real time by combining radiation monitor module, position monitors module and sending information nir-cable. Position monitor module developed using GPS-receiver and a micro controller ATMega8 based serial interrupts communication. Testing is done by testing communication between micro controller and GPS and also testing reading position by GPS receiver. From the test results concluded that the developed modules is good in serial communication is based on serial interrupts, good position measurement to be used outdoors and is not good enough for measurements indoors because the GPS receiver used is not using an outdoor antenna. (author)

  6. Safety culture and subcontractor network governance in a complex safety critical project

    International Nuclear Information System (INIS)

    Oedewald, Pia; Gotcheva, Nadezhda

    2015-01-01

    In safety critical industries many activities are currently carried out by subcontractor networks. Nevertheless, there are few studies where the core dimensions of resilience would have been studied in safety critical network activities. This paper claims that engineering resilience into a system is largely about steering the development of culture of the system towards better ability to anticipate, monitor, respond and learn. Thus, safety culture literature has relevance in resilience engineering field. This paper analyzes practical and theoretical challenges in applying the concept of safety culture in a complex, dynamic network of subcontractors involved in the construction of a new nuclear power plant in Finland, Olkiluoto 3. The concept of safety culture is in focus since it is widely used in nuclear industry and bridges the scientific and practical interests. This paper approaches subcontractor networks as complex systems. However, the management model of the Olkiluoto 3 project is to a large degree a traditional top-down hierarchy, which creates a mismatch between the management approach and the characteristics of the system to be managed. New insights were drawn from network governance studies. - Highlights: • We studied a relevant topical subject safety culture in nuclear new build project. • We integrated safety science challenges and network governance studies. • We produced practicable insights in managing safety of subcontractor networks

  7. Subcriticality monitoring method for reactor

    International Nuclear Information System (INIS)

    Ueda, Makoto.

    1991-01-01

    The present invention accurately monitors the reactor subcriticality and ensures the critical safety, irrespective of the presence or absence of artificial neutron sources. That is, when the subcriticality is monitored upon reactivity changing operation which causes reactivity change to the reactor during shutdown, neutron monitors are disposed at a plurality of monitoring positions. Then, neutron counting ratio before and after conducting the reactivity changing operation is determined. The subcriticality of the reactor is monitored by the ratio and the state of scattering of the ratio of neutron counting rate between each of the neutron monitors. With such procedures, signals of the neutron monitors are used, the characteristic that the change of the signals depend on the change of the neutron multiplication of the reactor core can be utilized whether artificial neutron sources (external neutron sources) are disposed or not. Accordingly, the subcriticality can be monitored more reliably. (I.S.)

  8. Road safety issues for bus transport management.

    Science.gov (United States)

    Cafiso, Salvatore; Di Graziano, Alessandro; Pappalardo, Giuseppina

    2013-11-01

    Because of the low percentage of crashes involving buses and the assumption that public transport improves road safety by reducing vehicular traffic, public interest in bus safety is not as great as that in the safety of other types of vehicles. It is possible that less attention is paid to the significance of crashes involving buses because the safety level of bus systems is considered to be adequate. The purpose of this study was to evaluate the knowledge and perceptions of bus managers with respect to safety issues and the potential effectiveness of various technologies in achieving higher safety standards. Bus managers were asked to give their opinions on safety issues related to drivers (training, skills, performance evaluation and behaviour), vehicles (maintenance and advanced devices) and roads (road and traffic safety issues) in response to a research survey. Kendall's algorithm was used to evaluate the level of concordance. The results showed that the majority of the proposed items were considered to have great potential for improving bus safety. The data indicated that in the experience of the participants, passenger unloading and pedestrians crossing near bus stops are the most dangerous actions with respect to vulnerable users. The final results of the investigation showed that start inhibition, automatic door opening, and the materials and internal architecture of buses were considered the items most strongly related to bus passenger safety. Brake assistance and vehicle monitoring systems were also considered to be very effective. With the exception of driver assistance systems for passenger and pedestrian safety, the perceptions of the importance of other driver assistance systems for vehicle monitoring and bus safety were not unanimous among the bus company managers who participated in this survey. The study results showed that the introduction of new technologies is perceived as an important factor in improving bus safety, but a better understanding

  9. Performance test of personal RF monitor for area monitoring at magnetic confinement fusion facility

    International Nuclear Information System (INIS)

    Tanaka, M.; Uda, T.; Wang, J.; Fujiwara, O.

    2012-01-01

    For safety management at a magnetic confinement fusion-test facility, protection from not only ionising radiation, but also non-ionising radiation such as the leakage of static magnetic and electromagnetic fields is an important issue. Accordingly, the use of a commercially available personal RF monitor for multipoint area monitoring is proposed. In this study, the performance of both fast- and slow-type personal RF monitors was investigated by using a transverse electromagnetic cell system. The range of target frequencies was between 10 and 300 MHz, corresponding to the ion cyclotron range of frequency in a fusion device. The personal RF monitor was found to have good linearity, frequency dependence and isotropic response. However, the time constant for the electric field sensor of the slow-type monitor was much longer than that for the fast-type monitor. Considering the time-varying field at the facility, it is found that the fast-type monitor is suitable for multipoint monitoring at magnetic confinement fusion test facilities. (authors)

  10. Facility effluent monitoring plan for the plutonium-uranium extraction facility

    International Nuclear Information System (INIS)

    Lohrasbi, J.; Johnson, D.L.; De Lorenzo, D.S.

    1993-12-01

    A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438-01. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. This facility effluent monitoring plan shall ensure long-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated at a minimum of every three years

  11. Facility effluent monitoring plan for the plutonium uranium extraction facility

    Energy Technology Data Exchange (ETDEWEB)

    Wiegand, D.L.

    1994-09-01

    A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438-01. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. This facility effluent monitoring plan shall ensure long-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated at a minimum of every three years.

  12. Facility effluent monitoring plan for the plutonium uranium extraction facility

    International Nuclear Information System (INIS)

    Wiegand, D.L.

    1994-09-01

    A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438-01. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. This facility effluent monitoring plan shall ensure long-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated at a minimum of every three years

  13. Facility effluent monitoring plan for the Plutonium Uranium Extraction Facility

    International Nuclear Information System (INIS)

    Greager, E.M.

    1997-01-01

    A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438-01. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether these systems are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. This facility effluent monitoring plan will ensure long-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated, at a minimum, every 3 years

  14. Facility effluent monitoring plan for the plutonium-uranium extraction facility

    Energy Technology Data Exchange (ETDEWEB)

    Lohrasbi, J.; Johnson, D.L. [Westinghouse Hanford Co., Richland, WA (United States); De Lorenzo, D.S. [Los Alamos Technical Associates, NM (United States)

    1993-12-01

    A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438-01. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. This facility effluent monitoring plan shall ensure long-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated at a minimum of every three years.

  15. Issues with monitoring the safety of psychoactive products under a legal regulated market for new psychoactive substances ('legal highs') in New Zealand.

    Science.gov (United States)

    Rychert, Marta; Wilkins, Chris; Witten, Karen

    2017-09-01

    New Zealand's Psychoactive Substances Act (2013) established the world's first regulated market for 'low risk' psychoactive products ('legal highs'). Under an interim PSA regime, 47 existing products were permitted to be continued to be sold. To explore issues with the implementation of regulatory systems to monitor the safety of products on the legal market under the interim Psychoactive Substances Act regime. Semi-structured interviews with 30 key stakeholders, including industry, government agency, health and drug service professionals were conducted, transcribed and analysed thematically. In retrospect stakeholders questioned the decision to approve strong synthetic cannabinoid smoking products, noting their health risks because of product formulation, inconsistent manufacturing practices and smoking as the means of administration. Industry actors claimed the decision to approve synthetic cannabinoid smokeable products prevented potentially safer products from gaining market share. The system for withdrawing approved products which were subsequently found to be harmful was criticised for the poor quality of data available, limited engagement with health professionals and the slowness of product withdrawal. Many of the problems with the regime were attributed to the urgency under which the legal market under the interim Psychoactive Substances Act was established and implemented. The selection of 'safer' products, implementation of the product monitoring system, and engagement with health professionals may have benefited from more time and resources. An incremental approach to establishing the new market may have made the regulatory management of the new regime more workable. [Rychert M, Wilkins C, Witten K. Issues with monitoring the safety of psychoactive products under a legal regulated market for new psychoactive substances ('legal highs') in New Zealand. Drug Alcohol Rev 2017;00:000-000]. © 2017 Australasian Professional Society on Alcohol and other Drugs.

  16. Improving the Efficiency of Administrative Decision-Making when Monitoring Reliability and Safety of Oil and Gas Equipment

    Directory of Open Access Journals (Sweden)

    Zemenkova Maria

    2016-01-01

    Full Text Available Methodology of rapid assessment of reliability index was developed based on system analysis of technological parameters. Within functioning of on-line monitoring system of reliability index of industrial facility this method allows to increase efficiency of making managerial decisions on technical and preventive maintenance. The technique is based on the analysis of technological parameters of operational modes of pipeline transport facilities registered by dispatcher controls. The created technique can be used by the operating, research, design institutes and oil and gas transport enterprises when declaring industrial safety. The received mathematical models allow federal services of supervision, the independent expert organizations to predict the development of reliability in the registered block of dispatching data either in real time mode, or taking into account the dynamics of service conditions of the object.

  17. NASA's Software Safety Standard

    Science.gov (United States)

    Ramsay, Christopher M.

    2007-01-01

    NASA relies more and more on software to control, monitor, and verify its safety critical systems, facilities and operations. Since the 1960's there has hardly been a spacecraft launched that does not have a computer on board that will provide command and control services. There have been recent incidents where software has played a role in high-profile mission failures and hazardous incidents. For example, the Mars Orbiter, Mars Polar Lander, the DART (Demonstration of Autonomous Rendezvous Technology), and MER (Mars Exploration Rover) Spirit anomalies were all caused or contributed to by software. The Mission Control Centers for the Shuttle, ISS, and unmanned programs are highly dependant on software for data displays, analysis, and mission planning. Despite this growing dependence on software control and monitoring, there has been little to no consistent application of software safety practices and methodology to NASA's projects with safety critical software. Meanwhile, academia and private industry have been stepping forward with procedures and standards for safety critical systems and software, for example Dr. Nancy Leveson's book Safeware: System Safety and Computers. The NASA Software Safety Standard, originally published in 1997, was widely ignored due to its complexity and poor organization. It also focused on concepts rather than definite procedural requirements organized around a software project lifecycle. Led by NASA Headquarters Office of Safety and Mission Assurance, the NASA Software Safety Standard has recently undergone a significant update. This new standard provides the procedures and guidelines for evaluating a project for safety criticality and then lays out the minimum project lifecycle requirements to assure the software is created, operated, and maintained in the safest possible manner. This update of the standard clearly delineates the minimum set of software safety requirements for a project without detailing the implementation for those

  18. Industrial Safety and Applied Health Physics Division, annual report for 1982

    International Nuclear Information System (INIS)

    1983-12-01

    Activities during the past year are summarized for the Health Physics Department, the Environmental Management Department, and the Safety Department. The Health Physics Department conducts radiation and safety surveys, provides personnel monitoring services for both external and internal radiation, and procures, services, and calibrates appropriate portable and stationary health physics instruments. The Environmental Management Department insures that the activities of the various organizations within ORNL are carried out in a responsible and safe manner. This responsibility involves the measurement, field monitoring, and evaluation of the amounts of radionuclides and hazardous materials released to the environment and the control of hazardous materials used within ORNL. The department also collaborates in the design of ORNL Facilities to help reduce the level of materials released to the environment. The Safety Department is responsible for maintaining a high level of staff safety. This includes aspects of both operational and industrial safety and also coordinates the activities of the Director's Safety Review Committee

  19. Industrial Safety and Applied Health Physics Division, annual report for 1982

    Energy Technology Data Exchange (ETDEWEB)

    1983-12-01

    Activities during the past year are summarized for the Health Physics Department, the Environmental Management Department, and the Safety Department. The Health Physics Department conducts radiation and safety surveys, provides personnel monitoring services for both external and internal radiation, and procures, services, and calibrates appropriate portable and stationary health physics instruments. The Environmental Management Department insures that the activities of the various organizations within ORNL are carried out in a responsible and safe manner. This responsibility involves the measurement, field monitoring, and evaluation of the amounts of radionuclides and hazardous materials released to the environment and the control of hazardous materials used within ORNL. The department also collaborates in the design of ORNL Facilities to help reduce the level of materials released to the environment. The Safety Department is responsible for maintaining a high level of staff safety. This includes aspects of both operational and industrial safety and also coordinates the activities of the Director's Safety Review Committee. (ACR)

  20. Facility Effluent Monitoring Plan for the Plutonium Finishing Plant (PFP); FINAL

    International Nuclear Information System (INIS)

    FRAZIER, T.P.

    1999-01-01

    A facility effluent monitoring plan is required by the U. S. Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether these systems are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. To ensure the long-range integrity of the effluent monitoring systems, an update to this facility effluent monitoring plan is required whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document is reviewed annually even if there are no operational changes, and is updated, at a minimum, every 3 years

  1. Next generation safety performance monitoring at signalized intersections using connected vehicle technology.

    Science.gov (United States)

    2014-08-01

    Crash-based safety evaluation is often hampered by randomness, lack of timeliness, and rarity of crash : occurrences. This is particularly the case for technology-driven safety improvement projects that are : frequently updated or replaced by newer o...

  2. Role of computers in CANDU safety systems

    International Nuclear Information System (INIS)

    Hepburn, G.A.; Gilbert, R.S.; Ichiyen, N.M.

    1985-01-01

    Small digital computers are playing an expanding role in the safety systems of CANDU nuclear generating stations, both as active components in the trip logic, and as monitoring and testing systems. The paper describes three recent applications: (i) A programmable controller was retro-fitted to Bruce ''A'' Nuclear Generating Station to handle trip setpoint modification as a function of booster rod insertion. (ii) A centralized monitoring computer to monitor both shutdown systems and the Emergency Coolant Injection system, is currently being retro-fitted to Bruce ''A''. (iii) The implementation of process trips on the CANDU 600 design using microcomputers. While not truly a retrofit, this feature was added very late in the design cycle to increase the margin against spurious trips, and has now seen about 4 unit-years of service at three separate sites. Committed future applications of computers in special safety systems are also described. (author)

  3. Automatic continuous monitoring system for dangerous sites and cargoes

    International Nuclear Information System (INIS)

    Smirnov, S.N.

    2009-01-01

    The problems of creation of automatic comprehensive continuous monitoring system for nuclear and radiation sites and cargoes of Rosatom Corporation, which carries out data collecting, processing, storage and transmission, including informational support to decision-making, as well as support to modelling and forecasting functions, are considered. The system includes components of two levels: site and industry. Currently the system is used to monitor over 8000 integrated parameters, which characterise the status of nuclear and radiation safety on Rosatom sites, environmental and fire safety

  4. Environmental Monitoring Plan, Revision 6

    Energy Technology Data Exchange (ETDEWEB)

    Gallegos, G M; Bertoldo, N A; Blake, R G; Campbell, C G; Grayson, A R; Nelson, J C; Revelli, M A; Rosene, C A; Wegrecki, T; Williams, R A; Wilson, K R; Jones, H E

    2012-03-02

    The purpose of environmental monitoring is to promote the early identification of, and response to, potential adverse environmental impacts associated with Lawrence Livermore National Laboratory (LLNL) operations. Environmental monitoring supports the Integrated Safety Management System (ISMS), International Organization for Standardization (ISO) 14001 Environmental Management Systems standard, and U. S. Department of Energy (DOE) Order 458.1, Radiation Protection of the Public and the Environment. Specifically, environmental monitoring enables LLNL to detect, characterize, and respond to releases from LLNL activities; assess impacts; estimate dispersal patterns in the environment; characterize the pathways of exposure to members of the public; characterize the exposures and doses to individuals and to the population; and to evaluate the potential impacts to the biota in the vicinity of LLNL. Environmental monitoring is also a major component of compliance demonstration for permits and other regulatory requirements. The Environmental Monitoring Plan (EMP) addresses the sample collection and analytical work supporting environmental monitoring to ensure the following: (1) A consistent system for collecting, assessing, and documenting environmental data of known and documented quality; (2) A validated and consistent approach for sampling and analysis of samples to ensure laboratory data meets program-specific needs and requirements within the framework of a performance-based approach for analytical laboratory work; and (3) An integrated sampling approach to avoid duplicative data collection. LLNL prepares the EMP because it provides an organizational framework for ensuring that environmental monitoring work, which is integral to the implementation of LLNL's Environmental Management System, is conducted appropriately. Furthermore, the Environmental Monitoring Plan helps LLNL ensure compliance with DOE Order 231.1 Change 2, Environment, Safety and Health Reporting

  5. WARMS - a continuous on-line environmental and emergency radiation monitoring system

    International Nuclear Information System (INIS)

    Ramsden, D.

    1984-01-01

    The Winfrith Airborne Release Monitoring System (WARMS) is used to monitor the environment around the Winfrith reactor site. It operates continuously monitoring the background radiation at 16 outstations and can provide rapid information should an accidental release occur. WARMS was developed jointly by the Radiological Safety Division and the Control and Instrumentation Division at Winfrith in association with the Safety and Reliability Directorate at Culcheth which developed the software. The system became operational in the autumn of 1983 and has since demonstrated a high degree of reliability and effectiveness. (author)

  6. Laser spectroscopy applied to environmental, ecological, food safety, and biomedical research.

    Science.gov (United States)

    Svanberg, Sune; Zhao, Guangyu; Zhang, Hao; Huang, Jing; Lian, Ming; Li, Tianqi; Zhu, Shiming; Li, Yiyun; Duan, Zheng; Lin, Huiying; Svanberg, Katarina

    2016-03-21

    Laser spectroscopy provides many possibilities for multi-disciplinary applications in environmental monitoring, in the ecological field, for food safety investigations, and in biomedicine. The paper gives several examples of the power of multi-disciplinary applications of laser spectroscopy as pursued in our research group. The studies utilize mostly similar and widely applicable spectroscopic approaches. Air pollution and vegetation monitoring by lidar techniques, as well as agricultural pest insect monitoring and classification by elastic scattering and fluorescence spectroscopy are described. Biomedical aspects include food safety applications and medical diagnostics of sinusitis and otitis, with strong connection to the abatement of antibiotics resistance development.

  7. Quantification of the safety status of PWR steam generators

    International Nuclear Information System (INIS)

    Bartonicek, J.; Jonas, O.; Schoeckle, F.

    1996-01-01

    The operational safety of components is affected during the period of operation (e.g., by loads and environmental effects). Additionally, changes in codes and standards can affect the safety margin of a component. In order to determine a quantitative status of the safety, the existing status of the component and the actual knowledge have to be regarded and evaluated. Differences (deficits) with respect to actual demands must be balanced by use of redundant measure to guarantee safety. The procedure is demonstrated using the steam generators of GKN 1 (German nuclear power plant--in operation since 1975) as an example. The existing status of the component regarding design and construction, material, load history (results of monitoring), the results of nondestructive testing and operational experience is determined and related to the actual regulatory and code compliance and to the state of the art in technics. Non-specified loads were measured in operation. Stress and fatigue analysis computations are performed on the base of realistic load patterns (results from monitoring). Thus the safety status can be quantified. Finally the GKN-concept of measures to guarantee the reliability and the safety of the component in future operation is discussed

  8. Non-intrusive long-term monitoring approaches

    International Nuclear Information System (INIS)

    Smathers, D.; Mangan, D.

    1998-01-01

    In order to promote internatinal confidence that the US and Russia are disarming per their commitments under Article 6 of the Non-Proliferation Treaty, an international verification regime may be applied to US and Russian excess fissile materials. Initially, it is envisioned that this verification regime would be applied at storage facilities; however, it should be anticipated that the verification regime would continue throughout any material disposition activities, should such activities be pursued. once the materials are accepted into the verification regime, it is assumed that long term monitoring will be used to maintain continuity of knowledge. The requirements for long term storage monitoring include unattended operation for extended periods of time, minimal intrusiveness on the host nation's safety and security activities, data collection incorporating data authentication, and monitoring redundancy to allow resolution of anomalies and to continue coverage in the event of equipment failures. Additional requirements include effective data review and analysis processes, operation during storage facility loading, procedure for removal of inventory items for safety-related surveillance, and low cost, reliable equipment. A monitoring system might include both continuous monitoring of storagecontainers and continuous area monitoring. These would be complemented with periodic on-site inspections. A fissile material storage facility is not a static operation. The initial studies have shown there are a number of valid reasons why a host nation may need them to remove material from the storage facility. A practical monitoring system must be able to accommodate necessary material movements

  9. MCO Monitoring activity description

    International Nuclear Information System (INIS)

    SEXTON, R.A.

    1998-01-01

    Spent Nuclear Fuel remaining from Hanford's N-Reactor operations in the 1970s has been stored under water in the K-Reactor Basins. This fuel will be repackaged, dried and stored in a new facility in the 200E Area. The safety basis for this process of retrieval, drying, and interim storage of the spent fuel has been established. The monitoring of MCOS in dry storage is a currently identified issue in the SNF Project. This plan outlines the key elements of the proposed monitoring activity. Other fuel stored in the K-Reactor Basins, including SPR fuel, will have other monitoring considerations and is not addressed by this activity description

  10. Heat exchanger performance monitoring guidelines

    International Nuclear Information System (INIS)

    Stambaugh, N.; Closser, W. Jr.; Mollerus, F.J.

    1991-12-01

    Fouling can occur in many heat exchanger applications in a way that impedes heat transfer and fluid flow and reduces the heat transfer or performance capability of the heat exchanger. Fouling may be significant for heat exchanger surfaces and flow paths in contact with plant service water. This report presents guidelines for performance monitoring of heat exchangers subject to fouling. Guidelines include selection of heat exchangers to monitor based on system function, safety function and system configuration. Five monitoring methods are discussed: the heat transfer, temperature monitoring, temperature effectiveness, delta P and periodic maintenance methods. Guidelines are included for selecting the appropriate monitoring methods and for implementing the selected methods. The report also includes a bibliography, example calculations, and technical notes applicable to the heat transfer method

  11. Safety and environmental aspect uranium mining and extraction in Kalan, Kalimantan

    International Nuclear Information System (INIS)

    Mudiar Masdja; Tampubolon, P.; Sihombing, W.

    1996-01-01

    Safety in uranium mining and extraction in Kalan, Kalimantan, Batan's activities, has been observed by concerning about personnel safety, monitoring of the work place and radiation surveillance. the personnel safety includes procurements of personnel protective equipment, work clothes, and washing facility. monitoring of the work place covers climate (temperature, humidity) noise frequency, poisonous gases, and tailing management. Radiation surveillance measures Rn gas and radioactive dust . Environmental assessment of Kalan site consist of physical, biological and cultural environments. The physical assessment mayor area such as water and air qualities, morphology and climatology. the biological assessment examines flora, fauna and aquatic biota. The culture assessment collect data of human population and distribution, occupation and income level, education, health and public perception. Guidelines for environmental management and monitoring have been documented and they have in Kalan site. (author). 8 refs; 3 tabs; 3 figs

  12. Criticality safety research on nuclear fuel cycle facility

    Energy Technology Data Exchange (ETDEWEB)

    Miyoshi, Yoshinori [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2004-07-01

    This paper present d s current status and future program of the criticality safety research on nuclear fuel cycle made by Japan Atomic Energy Research Institute. Experimental research on solution fuel treated in reprocessing plant has been performed using two critical facilities, STACY and TRACY. Fundamental data of static and transient characteristics are accumulated for validation of criticality safety codes. Subcritical measurements are also made for developing a monitoring system for criticality safety. Criticality safety codes system for solution and power system, and evaluation method related to burnup credit are developed. (author)

  13. 30 CFR 75.336 - Sampling and monitoring requirements.

    Science.gov (United States)

    2010-07-01

    ... concentration of other sampling locations in the sealed area and other required information. Before miners... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Sampling and monitoring requirements. 75.336... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Ventilation § 75.336 Sampling and...

  14. Propose Reactor Control and Monitoring System for RTP

    International Nuclear Information System (INIS)

    Mohd Sabri Minhat; Izhar Abu Hussin; Mohd Idris Taib; Mohd Khairulezwan Abdul Manan; Nurfarhana Ayuni Joha

    2011-01-01

    Reactor control and monitoring system is a one of the important features used in reactor. The control and monitoring must come together to provide safety, excellent performance and reliable in nuclear reactor technology application. Objectives of this technical paper are to design and propose reactor control system and reactor monitoring system in Research Reactor (RTP) for Reactor Upgrading Project. (author)

  15. Microwave alkaline roasting-water dissolving process for germanium extraction from zinc oxide dust and its analysis by response surface methodology (RSM)

    Science.gov (United States)

    Wang, Wankun; Wang, Fuchun; Lu, Fanghai

    2017-12-01

    Microwave alkaline roasting-water dissolving process was proposed to improve the germanium (Ge) extraction from zinc oxide (ZnO) dust. The effects of important parameters were investigated and the process conditions were optimized using response surface methodology (RSM). The Ge extraction is consistent with the linear polynomial model type. Alkali-material ratio, microwave heating temperature and leaching temperature are the significant factors for this process. The optimized conditions are obtained as follows, alkali-material ratio of 0.9 kg/kg, aging time of 1.12 day, microwave heating at 658 K for 10 min, liquid-solid ratio of 4.31 L/kg, leaching temperature at 330 K, leaching time of 47 min with the Ge extraction about 99.38%. It is in consistence with the predictive value of 99.31%. Compared to the existed alkaline roasting process heated by electric furnace in literature, the alkaline roasting temperature and holding time. It shows a good prospect on leaching Ge from ZnO dust with microwave alkaline roasting-water dissolving process.

  16. A bio-inspired memory model for structural health monitoring

    International Nuclear Information System (INIS)

    Zheng, Wei; Zhu, Yong

    2009-01-01

    Long-term structural health monitoring (SHM) systems need intelligent management of the monitoring data. By analogy with the way the human brain processes memories, we present a bio-inspired memory model (BIMM) that does not require prior knowledge of the structure parameters. The model contains three time-domain areas: a sensory memory area, a short-term memory area and a long-term memory area. First, the initial parameters of the structural state are specified to establish safety criteria. Then the large amount of monitoring data that falls within the safety limits is filtered while the data outside the safety limits are captured instantly in the sensory memory area. Second, disturbance signals are distinguished from danger signals in the short-term memory area. Finally, the stable data of the structural balance state are preserved in the long-term memory area. A strategy for priority scheduling via fuzzy c-means for the proposed model is then introduced. An experiment on bridge tower deformation demonstrates that the proposed model can be applied for real-time acquisition, limited-space storage and intelligent mining of the monitoring data in a long-term SHM system

  17. A bio-inspired memory model for structural health monitoring

    Science.gov (United States)

    Zheng, Wei; Zhu, Yong

    2009-04-01

    Long-term structural health monitoring (SHM) systems need intelligent management of the monitoring data. By analogy with the way the human brain processes memories, we present a bio-inspired memory model (BIMM) that does not require prior knowledge of the structure parameters. The model contains three time-domain areas: a sensory memory area, a short-term memory area and a long-term memory area. First, the initial parameters of the structural state are specified to establish safety criteria. Then the large amount of monitoring data that falls within the safety limits is filtered while the data outside the safety limits are captured instantly in the sensory memory area. Second, disturbance signals are distinguished from danger signals in the short-term memory area. Finally, the stable data of the structural balance state are preserved in the long-term memory area. A strategy for priority scheduling via fuzzy c-means for the proposed model is then introduced. An experiment on bridge tower deformation demonstrates that the proposed model can be applied for real-time acquisition, limited-space storage and intelligent mining of the monitoring data in a long-term SHM system.

  18. The level of knowledge and radiation safety practice amongst cardiovascular technology, medical assistant, nursing and diagnostic radiography students and dose monitoring in radiography laboratory of Kolej Islam Sains dan Teknologi, Kelantan

    International Nuclear Information System (INIS)

    Ainul Fadhlin Othman; Amran Abdul Majid

    2013-01-01

    Full-text: This study investigated the knowledge level and practices regarding radiation safety among the cardiovascular technology, medical assistant nursing and radiography diagnostic students of Kolej Islam Sains dan Teknologi (KIST). The objectives of this study are to monitor the dose rate at radiography lab and to propose the guideline on radiation safety topics to improve the syllabus. 274 respondents including 30 psychology students acting as the control group were asked to answer questions from the questionnaires which cover the topics of basic knowledge of radiation and radiation safety practice. There was a significant difference (p < 0.05) between the correct answers and courses for 18 questions except for the question 4. There was a significant different (p < 0.05) between the correct answers and year of study for the questions 4, 5, 7, 12 to 15 and 18 to 20. There was a significance different (p < 0.05) between the correct answers and gender for questions 7, 11 and 19. For area dose monitoring in the radiography diagnostic lab, the assessment report on film batches of 4 walls in the lab were recorded and Victoreen451-RYR survey meter was used to monitor the dose rate for 7 selected areas with the exposure factors set for the chest, abdomen, upper extremity, lower extremity and skull radiography examinations. The dose rates at area 1 to 4, area 5 during the examination of chest, abdomen and skull, area 6 during the examination of abdomen and area 7 during the examination of abdomen, had exceeded the dose limit for radiation worker. The dose rate at the area 1 and 4 are slightly higher than the other areas. The contributing factors are the distance, tube potential, collimation and X-ray tube angulation. This study had shown that the cardiovascular technology and diagnostic radiography students have better knowledge and radiation safety practice level than the medical assistant and nursing students. In general, the level of knowledge and radiation safety

  19. The establishment and implementation of safety culture policy in Indonesia

    International Nuclear Information System (INIS)

    Antariksawan, A.R.; Suharno; Arbie, B.

    2001-01-01

    This paper describes the progress in the establishment and implementation of safety culture in Indonesia, especially in BATAN, with special attention given to the development of safety culture indicators. The spirit of safety culture implementation is marked firstly by declaration of Policy Statement by the Head of BATAN. In order to monitor the implementation of safety culture, six indicators are established. Based on those indicators, it is seemed that at present the progress of implementation of safety culture is quite good enough. (author)

  20. The enhancement of Ignalina NPP in design and operational safety

    International Nuclear Information System (INIS)

    Negrivoda, G.

    1999-01-01

    Enhancement of Ignalina NPP design include: core design improvements; fuel channel integrity (multiple pressure tube rupture); improvements of shutdown systems; improvements of instrumentation and control devices; containment strength and tightness; design basis accident analysis; improvements of safety and support systems; seismic safety enhancement; Year 2000 project; cracks in pipes. Enhancement of operational safety includes: quality assurance; configuration management; safety management and safety culture; emergency operating procedures; training and full scope simulator; in-service inspection; fire protection and ageing monitoring and management

  1. The origin of high magnetic properties in (R,Zr)(Fe,Co){sub 11.0–11.5}Ti{sub 1.0–0.5}N{sub y} (y=1.0–1.4 for R=Nd, y=0 for R=Sm) compounds

    Energy Technology Data Exchange (ETDEWEB)

    Kobayashi, K., E-mail: koba@ms.sist.ac.jp [Shizuoka Institute of Science and Technology, 2200-2 Toyosawa, Fukuroi, Shizuoka 437-8555 (Japan); Suzuki, S.; Kuno, T.; Urushibata, K. [Shizuoka Institute of Science and Technology, 2200-2 Toyosawa, Fukuroi, Shizuoka 437-8555 (Japan); Sakuma, N.; Yano, M.; Shoji, T.; Kato, A. [Toyota Motor Corporation, 1200 Mishuku, Susono, Shizuoka 410-1193 (Japan); Technology Reserch Association of Magnetic Materials fot High-efficiency Motors (Mag-HEM) Higashifuji-Branch, 1200 Mishuku, Susono, Shizuoka 410-1193, Japan. (Japan); Manabe, A. [Technology Reserch Association of Magnetic Materials fot High-efficiency Motors (Mag-HEM) Higashifuji-Branch, 1200 Mishuku, Susono, Shizuoka 410-1193, Japan. (Japan)

    2017-03-15

    Ten alloys and nitrogenated compounds of (R,Zr)(Fe,Co){sub 11.0–11.5}Ti{sub 1.0–0.5}N{sub y} (y=1.0–1.4 for R=Nd, y=0 for R=Sm) with a ThMn{sub 12}-type structure were prepared. The average Fe–Fe interatomic distances, d(Fe–Fe), for Fe sites were calculated based on the reported atomic parameters. The hyperfine splittings (inner field (IF), in teslas) were measured by Mössbauer spectroscopy, and the IF increased with increasing d(Fe–Fe) for Fe sites, indicating a magneto-volume effect. The order of IF magnitude in Fe sites was Fe(8i)>Fe(8j)>Fe(8f) in all alloys. Co substitution for Fe sites, (Fe{sub 0.75}Co{sub 0.25}), increased the IF by 25% for the R=Nd alloy and 15% for the R=Sm alloy. Decreasing Ti content from −Ti{sub 1.0} to −Ti{sub 0.5}, which increased the Fe and Co content, preserved the ThMn{sub 12} structure with Zr substitution for R(2a) sites, and caused a slight increase in the IF of 2% for the R=Nd alloy and 7% for the R=Sm alloy. Nitrogenation, where N was introduced into the 2b sites, also increased IF in R=Nd alloys, by 23% for the Co- and Zr-free alloys, NdFe{sub 11}Ti{sub 1.0}N{sub 1.5}, and by 7% for the Co-containing, (Nd{sub 0.7}Zr{sub 0.3}) (Fe{sub 0.75}Co{sub 0.25}) {sub 11.5}Ti{sub 0.5}N{sub 1.3} alloy. The IF values of the R=Nd alloys were slightly larger than those of the R=Sm alloys. In conclusion, the magneto-volume effect was clearly observed at the Fe sites, and Co substitution into Fe sites and nitrogenation (R=Nd alloys) compensated for the increased IF. Increasing the Fe and Co fractions also increased IF slightly. - Highlights: • Average distances of Fe–Fe (d(Fe–Fe)) were calculated using lattice constants. • Hyperfine fields (IF) in Fe sites were measured using Mössbauer spectroscopy. • Relationship between d(Fe–Fe) and IF at each Fe site was obtained. • Co substitution and N introduction effects on IF was also measured. • Magneto-volume effect is main reason of IF augmentation in Fe sites.

  2. Facility effluent monitoring plan for the plutonium-uranium extraction facility

    International Nuclear Information System (INIS)

    Thompson, R.J.; Sontage, S.

    1991-11-01

    A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. This facility effluent monitoring plan is the first annual report. It shall ensure long-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated as a minimum every three years

  3. Safety status system for operating room devices.

    Science.gov (United States)

    Guédon, Annetje C P; Wauben, Linda S G L; Overvelde, Marlies; Blok, Joleen H; van der Elst, Maarten; Dankelman, Jenny; van den Dobbelsteen, John J

    2014-01-01

    Since the increase of the number of technological aids in the operating room (OR), equipment-related incidents have come to be a common kind of adverse events. This underlines the importance of adequate equipment management to improve the safety in the OR. A system was developed to monitor the safety status (periodic maintenance and registered malfunctions) of OR devices and to facilitate the notification of malfunctions. The objective was to assess whether the system is suitable for use in an busy OR setting and to analyse its effect on the notification of malfunctions. The system checks automatically the safety status of OR devices through constant communication with the technical facility management system, informs the OR staff real-time and facilitates notification of malfunctions. The system was tested for a pilot period of six months in four ORs of a Dutch teaching hospital and 17 users were interviewed on the usability of the system. The users provided positive feedback on the usability. For 86.6% of total time, the localisation of OR devices was accurate. 62 malfunctions of OR devices were reported, an increase of 12 notifications compared to the previous year. The safety status system was suitable for an OR complex, both from a usability and technical point of view, and an increase of reported malfunctions was observed. The system eases monitoring the safety status of equipment and is a promising tool to improve the safety related to OR devices.

  4. Safety parameter display system for Kalinin NPP

    International Nuclear Information System (INIS)

    Andreev, V.I.; Videneev, E.N.; Tissot, J.C.; Joonekindt, D.; Davidenko, N.N.; Shaftan, G.I.; Dounaev, V.G.; Neboyan, V.T.

    1995-01-01

    The paper discusses the safety parameter display system (SPDS), which is being designed for Kalinin NPP. The assessment of the safety status of the plant is done by the continuous monitoring of six critical safety functions and the corresponding status trees. Besides, a number of additional functions are realized within the scope of KlnNPP, aimed at providing the operator and the safety engineer in the main control room with more detailed information in accidental situation as well as during the normal operation. In particular, these functions are: archiving, data logs and alarm handling, safety actions monitoring, mnemonic diagrams indicating the state of main technological equipment and basic plant parameters, reference data, etc. As compared with the traditional scope of functions of this kind of systems, the functionality of KlnNPP SPDS is significantly expanded due to the inclusion in it the operator support function ''computerized procedures''. The basic SPDS implementation platform is ADACS of SEMA GROUP design. The system architecture includes two workstations in the main control room: one is for reactor operator and the other one for safety engineer. Every station has two CRT screens which ensures computerized procedures implementation and provides for extra services for the operator. Also, the information from the SPDS is transmitted to the local crisis center and to the crisis center of the State utility organization concern ''Rosenergoatom''. (author). 3 refs, 6 figs, 1 tab

  5. AEC controlled area safety program

    Energy Technology Data Exchange (ETDEWEB)

    Hendricks, D W [Nevada Operations Office, Atomic Energy Commission, Las Vegas, NV (United States)

    1969-07-01

    The detonation of underground nuclear explosives and the subsequent data recovery efforts require a comprehensive pre- and post-detonation safety program for workers within the controlled area. The general personnel monitoring and environmental surveillance program at the Nevada Test Site are presented. Some of the more unusual health-physics aspects involved in the operation of this program are also discussed. The application of experience gained at the Nevada Test Site is illustrated by description of the on-site operational and safety programs established for Project Gasbuggy. (author)

  6. AEC controlled area safety program

    International Nuclear Information System (INIS)

    Hendricks, D.W.

    1969-01-01

    The detonation of underground nuclear explosives and the subsequent data recovery efforts require a comprehensive pre- and post-detonation safety program for workers within the controlled area. The general personnel monitoring and environmental surveillance program at the Nevada Test Site are presented. Some of the more unusual health-physics aspects involved in the operation of this program are also discussed. The application of experience gained at the Nevada Test Site is illustrated by description of the on-site operational and safety programs established for Project Gasbuggy. (author)

  7. Biomonitoring at the UK Health and Safety Laboratory.

    Science.gov (United States)

    Cocker, J; Jones, K; Morton, J; Mason, H J

    2007-05-01

    The UK Health and Safety Laboratory (HSL) provides research and analytical support to the Health and Safety Executive, other Government Departments and employers. In the area of biomonitoring HSL conducts research studies and provides an analytical service for regular surveillance of worker exposure to hazardous substances. This paper gives brief examples of how data from such studies can be used to develop biological monitoring guidance values for isocyanates, polycyclic aromatic hydrocarbons and hexavalent chromium. In addition, a study of occupational exposure to copper chrome arsenic wood preservatives is briefly described to show how biological monitoring can be used for post-approval surveillance of a biocide.

  8. Study on Reactor Performance of Online Power Monitoring in PUSPATI TRIGA Reactor (RTP)

    International Nuclear Information System (INIS)

    Zareen Khan Abdul Jalil Khan; Ridzuan Abdul Mutalib; Mohd Sabri Minhat

    2014-01-01

    The Reactor TRIGA PUSPATI (RTP) at Malaysia Nuclear Agency is a TRIGA Mark II type reactor and pool type cooled by natural circulation of light water. This paper describe on reactor performance of online power monitoring based on various parameter of reactor such as log power, linear power, period, Fuel and coolant temperature and reactivity parameter with using neutronic and other instrumentation system of reactor. Methodology of online power estimation and monitoring is to evaluate and analysis of reactor power which is important of reactor safety and control. Neutronic instrumentation system will use to estimate power measurement, differential of log and linear power and period during reactor operation .This study also focus on noise fluctuation from fission chamber during reactor operation .This work will present result of online power monitoring from RTP which indicated the safety parameter identification and initiate safety action on crossing the threshold set point trip. Conclude that optimization of online power monitoring will improved the reactor control and safety parameter of reactor during operation. (author)

  9. Gas House Autonomous System Monitoring

    Science.gov (United States)

    Miller, Luke; Edsall, Ashley

    2015-01-01

    Gas House Autonomous System Monitoring (GHASM) will employ Integrated System Health Monitoring (ISHM) of cryogenic fluids in the High Pressure Gas Facility at Stennis Space Center. The preliminary focus of development incorporates the passive monitoring and eventual commanding of the Nitrogen System. ISHM offers generic system awareness, adept at using concepts rather than specific error cases. As an enabler for autonomy, ISHM provides capabilities inclusive of anomaly detection, diagnosis, and abnormality prediction. Advancing ISHM and Autonomous Operation functional capabilities enhances quality of data, optimizes safety, improves cost effectiveness, and has direct benefits to a wide spectrum of aerospace applications.

  10. Nuclear power plant control room operator control and monitoring tasks

    International Nuclear Information System (INIS)

    Bovell, C.R.; Beck, M.G.; Carter, R.J.

    1998-01-01

    Oak Ridge National Laboratory is conducting a research project the purpose of which is to develop the technical bases for regulatory review criteria for use in evaluating the safety implications of human factors associated with the use of artificial intelligence and expert systems, and with advanced instrumentation and control (I and C) systems in nuclear power plants (NPP). This report documents the results from Task 8 of that project. The primary objectives of the task was to identify the scope and type of control and monitoring tasks now performed by control-room operators. Another purpose was to address the types of controls and safety systems needed to operate the nuclear plant. The final objective of Task 8 was to identify and categorize the type of information and displays/indicators required to monitor the performance of the control and safety systems. This report also discusses state-of-the-art controls and advanced display devices which will be available for use in control-room retrofits and in control room of future plants. The fundamental types of control and monitoring tasks currently conducted by operators can be divided into four classifications: function monitoring tasks, control manipulation tasks, fault diagnostic tasks, and administrative tasks. There are three general types of controls used in today's NPPs, switches, pushbuttons, and analog controllers. Plant I and C systems include components to achieve a number of safety-related functions: measuring critical plant parameters, controlling critical plant parameters within safety limits, and automatically actuating protective devices if safe limits are exceeded. The types of information monitored by the control-room operators consist of the following parameters: pressure, fluid flow and level, neutron flux, temperature, component status, water chemistry, electrical, and process and area radiation. The basic types of monitoring devices common to nearly all NPP control rooms include: analog meters

  11. The organization of research reactor safety in the UKAEA

    International Nuclear Information System (INIS)

    Redpath, W.

    1983-01-01

    The present state of organization and development of research reactor safety in the UKAEA are outlined by addressing the fundamental safety principles which have been adopted in keeping with national health and safety requirement. The organisation, assessment and monitoring of research reactor safety on complex multi-discipline and multi-activity nuclear research and development site are discussed. Methods of safety assessment, such as probabilistic risk assessment and risk acceptance criteria, which have been developed and applied in practice are explained, and some indication of the directions in which some of the current developments in the safety of UKAEA research reactors is also included. (A.J.)

  12. Summary of industrial impacts from recycled radioactive scrap metals

    International Nuclear Information System (INIS)

    Dehmel, J.-C.; Harrop, J.; MacKinney, J.A.

    1995-01-01

    During operation, decontamination, and dismantlement, nuclear facilities are generating significant quantities of radioactive scrap metal (RSM). Future decommissioning will generate even more RSM. The petroleum industry also generates RSM in the form of equipment contaminated with naturally occurring radioactivity. Finally, the accidental melting of radioactive sources in steel mills has generated smaller amounts of contaminated metals. Steel mills, smelters, and foundries could recycle these materials, which might then appear in finished products or as feedstocks used by other industries. If introduced in this manner, residual radioactivity can adversely affect the performance of certain products. Such products include computers and other devices that rely on integrated circuits. The most important effect of residual radioactivity on integrated circuits is a phenomenon known as 'single event upsets or soft errors.' Radioactivity can also adversely affect the performance of products such as photographic film and components designed to measure the presence of radioactivity. Radioactivity that raises background count-rates to higher levels could affect the performance of radiation monitoring systems and analytical equipment. Higher background count-rates would lead to reduced sensitivity and lower resolution in spectroscopic systems. The computer, photographic, and radiation measurement industries have taken steps to minimize the impact of residual radioactivity on their products. These steps include monitoring manufacturing processes, specifying material acceptance standards, and screening suppliers. As RSM is recycled, these steps may become more important and more costly. This paper characterizes potentially impacted industries and vulnerability and effects due to the presence of residual radioactivity. Finally, the paper describes practices used to limit the impact of residual radioactivity. (J.P.N.)

  13. Sterilization Monitoring management of the integration of the operating room with CSSD

    Directory of Open Access Journals (Sweden)

    Shu-yan XIA

    2014-08-01

    Full Text Available Objective: Explore the Sterilization Monitoring management of the integration of the operating room with CSSD. Methods: Compare sterilization process monitoring with biological monitoring and chemical monitoring. Results: The management in Biological monitoring, chemical monitoring and sterilization process monitoring is crucial. Conclusion: Sterilization monitoring is to ensure the safe use of sterile goods so as to protect the safety of surgical patients.

  14. The probability safety assessment impact on the BR2 refurbishment

    International Nuclear Information System (INIS)

    Pouleur, Yvan

    1995-01-01

    The probabilistic safety assessment (PSA) study has proven its worth by establishing a sensitive safety screening of the reactor. It has focused engineering forces to technically improve safety systems and to measure the influence of functional modifications. In the future, the project will be developed in a living way, to reinforce the present structure along with continuous safety monitoring of the reactor and to develop engineers and operators safety skills. This paper presents the PSA impact on the BR2 (Belgian Reactor Two) refurbishment. (author)

  15. Preparation, characterization, uranium (VI) biosorption models, and conditions optimization by response surface methodology (RSM) for amidoxime-functionalized marine fungus materials

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Xuechun; Gao, Yang; Jiang, Min; He, Dianxiong; Liao, Sen; Hou, Dan; Yan, Xueming; Long, Wei; Wu, Yaxin; Tan, Ni [Univ. of South China, Hengyang (China). School of Chemistry and Chemical Engineering

    2017-08-01

    Amidoxime-functionalized marine fungus Fusarium sp. ZZF51 (ZGDA) was synthesized and studied to adsorb uranium (VI) from the aqueous solution. Different instrumental techniques such as FTIR, SEM, and TGA were employed for the characterization of the manufactured materials, and theirs ability of removal uranium (VI) was optimized using RSM. The experimental results showed the maximum adsorption capacity for the synthesized materials was 230.78 mg g{sup -1} at the following optimization conditions: S-L ratio 150 mg L{sup -1}, pH 5.13, uranium (VI) initial concentration 40 mg L{sup -1}, and equilibrium time 122.40 min. More than 85% of the absorbed uranium (VI) could be desorbed by 0.5 or 1.0 mol L{sup -1} HCl, and the modified mycelium could be reused at least five times. The thermodynamic experimental data of adsorption uranium (VI) could fit better with Langmuir and Freundlich isotherms models, and the pseudo-second-order model was better to interpret the kinetics process. The modified fungus materials exhibited the better sorption capacity for uranium (VI) in comparison with raw biomass should be attributed to the strong chelation of amidoxime to uranium (VI) ions.

  16. Main findings, conclusions and recommendations of the Ignalina Safety Panel

    International Nuclear Information System (INIS)

    Birkhofer, A.

    1999-01-01

    Ignalina Safety Panel was created to define, monitor and supervise the scope and production of the Ignalina Safety Analysis Report (SAR) and its Review (RSR); to review results of in-depth safety assessment addressing important contradictory statements; to give Lithuanian Government recommendations in view of further licensing process. In this paper General and Specific Recommendations provided by the Panel are presented

  17. Status of safety in nuclear facilities - 2012. AREVA General Inspectorate Annual report

    International Nuclear Information System (INIS)

    2013-05-01

    After a message from the Areva's Chief Executive Officer and a message from the senior Vice President of safety, health, security, sustainable development, a text by the inspector general comments the key safety results (events, dose levels, radiological impacts), the inspection findings, the areas of vigilance (relationship with the ASN, the management of the criticality risk, and facility compliance), some significant topics after the Fukushima accident. Then this report addresses the status of nuclear safety and radiation protection in the group's facilities and operations. It more specifically addresses the context and findings (lessons learned from the inspections, operating experience from event, employee radiation monitoring, environmental monitoring), crosscutting processes (safety management, controlling facility compliance, subcontractor guidance and management, crisis management), specific risks (criticality risk, fire hazards, transportation safety, radioactive waste management, pollution prevention, liability mitigation and dismantling), and areas for improvement and outlook

  18. Safety Aspects of Sustainable Storage Dams and Earthquake Safety of Existing Dams

    Directory of Open Access Journals (Sweden)

    Martin Wieland

    2016-09-01

    Full Text Available The basic element in any sustainable dam project is safety, which includes the following safety elements: ① structural safety, ② dam safety monitoring, ③ operational safety and maintenance, and ④ emergency planning. Long-term safety primarily includes the analysis of all hazards affecting the project; that is, hazards from the natural environment, hazards from the man-made environment, and project-specific and site-specific hazards. The special features of the seismic safety of dams are discussed. Large dams were the first structures to be systematically designed against earthquakes, starting in the 1930s. However, the seismic safety of older dams is unknown, as most were designed using seismic design criteria and methods of dynamic analysis that are considered obsolete today. Therefore, we need to reevaluate the seismic safety of existing dams based on current state-of-the-art practices and rehabilitate deficient dams. For large dams, a site-specific seismic hazard analysis is usually recommended. Today, large dams and the safety-relevant elements used for controlling the reservoir after a strong earthquake must be able to withstand the ground motions of a safety evaluation earthquake. The ground motion parameters can be determined either by a probabilistic or a deterministic seismic hazard analysis. During strong earthquakes, inelastic deformations may occur in a dam; therefore, the seismic analysis has to be carried out in the time domain. Furthermore, earthquakes create multiple seismic hazards for dams such as ground shaking, fault movements, mass movements, and others. The ground motions needed by the dam engineer are not real earthquake ground motions but models of the ground motion, which allow the safe design of dams. It must also be kept in mind that dam safety evaluations must be carried out several times during the long life of large storage dams. These features are discussed in this paper.

  19. Pre-Exposure Prophylaxis for HIV Prevention: Safety Concerns.

    Science.gov (United States)

    Tetteh, Raymond A; Yankey, Barbara A; Nartey, Edmund T; Lartey, Margaret; Leufkens, Hubert G M; Dodoo, Alexander N O

    2017-04-01

    Available evidence supports the efficacy of pre-exposure prophylaxis (PrEP) in decreasing the incidence of human immunodeficiency virus (HIV) infection among high-risk individuals, especially when used in combination with other behavioural preventive methods. Safety concerns about PrEP present challenges in the implementation and use of PrEP. The aim of this review is to discuss safety concerns observed in completed clinical trials on the use of PrEP. We performed a literature search on PrEP in PubMed, global advocacy for HIV prevention (Aids Vaccine Advocacy Coalition) database, clinical trials registry " http://www.clinicaltrials.gov " and scholar.google, using combination search terms 'pre-exposure prophylaxis', 'safety concerns in the use of pre-exposure prophylaxis', 'truvada use as PrEP', 'guidelines for PrEP use', 'HIV pre-exposure prophylaxis' and 'tenofovir' to identify clinical trials and literature on PrEP. We present findings associated with safety issues on the use of PrEP based on a review of 11 clinical trials on PrEP with results on safety and efficacy as at April 2016. We also reviewed findings from routine real-life practice reports. The pharmacological intervention for PrEP was tenofovir disoproxil fumarate/emtricitabine in a combined form as Truvada ® or tenofovir as a single entity. Both products are efficacious for PrEP and seem to have a good safety profile. Regular monitoring is recommended to prevent long-term toxic effects. The main adverse effects observed with PrEP are gastrointestinal related; basically mild to moderate nausea, vomiting and diarrhea. Other adverse drug effects worth monitoring are liver enzymes, renal function and bone mineral density. PrEP as an intervention to reduce HIV transmission appears to have a safe benefit-risk profile in clinical trials. It is recommended for widespread use but adherence monitoring and real-world safety surveillance are critical in the post-marketing phase to ensure that the benefits

  20. Radiological monitoring. Controlling surface water pollution

    International Nuclear Information System (INIS)

    Morin, Maxime

    2018-01-01

    Throughout France, surface waters (from rivers to brooks) located at the vicinity of nuclear or industrial sites, are subject to regular radiological monitoring. An example is given with the radiological monitoring of a small river near La Hague Areva's plant, where contaminations have been detected with the help of the French IRSN nuclear safety research organization. The sampling method and various measurement types are described