Advanced Business Impact Analysis : Verbeterd risico-management door gericht impactbepaling. Dl.1

NARCIS (Netherlands)

Kooij-Janic, M.; Verweij, E.D.N.

2015-01-01

Alle bedrijven lopen risico’s, waardoor er een kans bestaat dat bedrijven hun verplichtingen naar hun stakeholders - zoals klanten of aandeelhouders - niet meer kunnen nakomen en daardoor zelf schade leiden. Het is dus van vitaal belang dat bedrijven de relevante risico’s identificeren en vervolgens

Advanced Business Impact Analysis : Verbeterd risico-management door gericht impactbepaling. Dl.2

NARCIS (Netherlands)

Kooij-Janic, M.; Verweij, E.D.N.

2015-01-01

Alle bedrijven lopen risico’s, waardoor er een kans bestaat dat bedrijven hun verplichtingen naar hun stakeholders - zoals klanten of aandeelhouders - niet meer kunnen nakomen en daardoor zelf schade leiden. Het is dus van vitaal belang dat bedrijven de relevante risico’s identificeren en vervolgens

Quasirelativistic calculation of 4s24p5, 4s24p44d and 4s4p6 configuration spectroscopic parameters for the W39+ ion

International Nuclear Information System (INIS)

Bogdanovich, P; Karpuškienė, R; Kisielius, R

2015-01-01

The ab initio quasirelativistic Hartree–Fock method developed specifically for the calculation of spectral parameters of heavy atoms and highly charged ions is used to derive spectral data for the 4s 2 4p 5 , 4s 2 4p 4 4d and 4s4p 6 configurations of the multicharged tungsten ion W 39+ . The relativistic effects are taken into account in the Breit–Pauli approximation for the quasirelativistic Hartree–Fock radial orbitals. The configuration interaction method is applied to include the electron correlation effects. Produced data are compared with existing experimental measurements and theoretical calculations. (paper)

The hyperfine structure constants for the 4s24p and 4s25s states of Ga

International Nuclear Information System (INIS)

Wang Qingmin; Dong Chenzhong

2012-01-01

The hyperfine structure (hfs) constants for the states 4s 2 4p 2 P 1/2,3/2 and 4s 2 5s 2 S 1/2 of 71 Ga were calculated using the GRASP2K package based on the multiconfiguration Dirac-Fock (MCDF) method. The results indicated that the core polarization effect was important for the hyperfine structure constants. (authors)

75 FR 60129 - Draft Guidance for Industry and Investigators on Safety Reporting Requirements for...

Science.gov (United States)

2010-09-29

...., Bldg. 51, rm. 2201, Silver Spring, MD 20993-0002; or the Office of Communication, Outreach, and...'s ability to review critical safety information, improve safety monitoring of human drug and..., will represent the Agency's current thinking on safety reporting requirements for INDs and BA/BE...

“Civis romana sum”. La Londra intertestuale di Bernardine Evaristo

Directory of Open Access Journals (Sweden)

Samanta Trivellini

2012-12-01

Full Text Available Bernardine Evaristo’s novel in verse The Emperor’s Babe (2001 features the story of Zuleika, the daughter of Nubian immigrants, who lives in Roman London at the beginning of the third century A.D.. Evaristo’s sources are both classical – Latin poetry, proverbs, mottos, myths, as well as material culture – and modern – for example, Oscar Wilde’s perspective on history informs the revisionist intent of the novel.This article aims to examine the role of quotations and intertextual echoes in the development of the storyline and in the dialectic between past and present. If apparently they contribute to the recreation of the ancient cultural background, at a deeper level, they also engender ironic tensions and parodic effects through discrepancies in tone, style and narrative situations. Moreover, in relation to the protagonist’s gendered and subaltern position, quotations and other references are a crucial aspect of Evaristo’s rewriting of history: by mapping today’s post-imperial and multicultural London on to the Roman city, The Emperor’s Babe subverts the myth of the nation at its roots.

Hoe goed bent u 'in control' over de robuustheid van uw ICT-keten?

NARCIS (Netherlands)

Bastiaansen, H.J.M.; Joosten, H.J.M.; Meeuwissen, H.B.; Roijers, F.

2011-01-01

ICT-ketens worden enerzijds steeds complexer en anderzijds van steed vitaler belang voor de maatschappij en voor organisaties. Daarbij neemt ook het belang van robuustheid van ICT-ketens en de beheersing daarvan toe. De auteurs beschrijven een nieuwe methodiek waarmee de mate van beheersing van de

Electron excitation cross sections for the 2s(2)2p(3)4S(O) -- 2s(2)2p(3)2D(O) (forbidden) and 4S(O) -- 2s2p(4) 4P (resonance) transitions in O II

Science.gov (United States)

Zuo, M.; Smith, Steven J.; Chutjian, A.; Williams, I. D.; Tayal, S. S.; Mclaughlin, Brendan M.

1995-01-01

Experimental and theoretical excitation cross sections are reported for the first forbidden transition 4S(O) -- 2S(2)2p(3) 2D(O) (lambda-lambda 3726, 3729) and the first allowed (resonance) transition 4S(O) -- 2s2p(4) 4P(lambda-833) in O II. Use is made of electron energy loss and merged-beams methods. The electron energy range covered is 3.33 (threshold) to 15 eV for the S -- D transition, and 14.9 (threshold) to 40 eV for the S -- P transition. Care was taken to assess and minimize the metastable fraction of the O II beam. An electron mirror was designed and tested to reflect inelastically backscattered electrons into the forward direction to account for the full range of polar scattering angles. Comparisons are made between present experiments and 11-state R-matrix calculations. Calculations are also presented for the 4S(O) -- 2s(2)2p(3)2P(O) (lambda-2470) transition.

Calculation of the total electron excitation cross section in the Born approximation using Slater wave functions for the Li (2s yields 2p), Li (2s yields 3p), Na (3s yields 4p), Mg (3p yields 4s), Ca (4s yields 4p) and K (4s yields 4p) excitations. M.S. Thesis

Science.gov (United States)

Simsic, P. L.

1974-01-01

Excitation of neutral atoms by inelastic scattering of incident electrons in gaseous nebulae were investigated using Slater Wave functions to describe the initial and final states of the atom. Total cross sections using the Born Approximation are calculated for: Li(2s yields 2p), Na(3s yields 4p), k(4s yields 4p). The intensity of emitted radiation from gaseous nebulae is also calculated, and Maxwell distribution is employed to average the kinetic energy of electrons.

N4H9Cu7S4: a hydrazinium-based salt with a layered Cu7S4- framework.

Science.gov (United States)

Mitzi, David B

2007-02-05

Crystals of a hydrazinium-based copper(I) sulfide salt, N4H9Cu7S4 (1), have been isolated by an ambient temperature solution-based process. In contrast to previously reported hydrazinium salts of main-group metal chalcogenides, which consist of isolated metal chalcogenide anions, and ACu7S4 (A = NH4+, Rb+, Tl+, K+), which contains a more three-dimensional Cu7S4- framework with partial Cu-site occupancy, the structure of 1 [P21, a = 6.8621(4) A, b = 7.9851(4) A, c = 10.0983(5) A, beta = 99.360(1) degrees , Z = 2] is composed of extended two-dimensional Cu7S4- slabs with full Cu-site occupancy. The Cu7S4- slabs are separated by a mixture of hydrazinium and hydrazine moieties. Thermal decomposition of 1 into copper(I) sulfide proceeds at a significantly lower temperature than that observed for analogous hydrazinium salts of previously considered metal chalcogenides, completing the transition at temperatures as low as 120 degrees C. Solutions of 1 may be used in the solution deposition of a range of Cu-containing chalcogenide films.

Tungsten phosphanylarylthiolato complexes [W{PhP(2-SC6H4)2-kappa3S,S',P} 2] and [W{P(2-SC6H4)3-kappa4S,S',S",P}2]: synthesis, structures and redox chemistry.

Science.gov (United States)

Hildebrand, Alexandra; Lönnecke, Peter; Silaghi-Dumitrescu, Luminita; Hey-Hawkins, Evamarie

2008-09-14

PhP(2-SHC6H4)2 (PS2H2) reacts with WCl6 with reduction of tungsten to give the air-sensitive tungsten(IV) complex [W{PhP(2-SC6H4)2-kappa(3)S,S',P}2] (1). 1 is oxidised in air to [WO{PhPO(2-SC6H4)2-kappa(3)S,S',O}{PhP(2-SC6H4)2-kappa(3)S,S',P}] (2). The attempted synthesis of 2 by reaction of 1 with iodosobenzene as oxidising agent was unsuccessful. [W{P(2-SC6H4)3-kappa(4)S,S',S",P}2] (3) was formed in the reaction of P(2-SHC6H4)3 (PS3H3) with WCl6. The W(VI) complex 3 contains two PS3(3-) ligands, each coordinated in a tetradentate fashion resulting in a tungsten coordination number of eight. The reaction of 3 with AgBF4 yields the dinuclear tungsten complex [W2{P(2-SC6H4)3-kappa(4)S,S',S",P}3]BF4 (4). Complexes 1-4 were characterised by spectral methods and X-ray structure determination.

Ethical standards for the occupational health-nursing practitioner regarding the HIV positive person in the workplace

Directory of Open Access Journals (Sweden)

M Otto

2001-10-01

Die beroepsgesondheidsverpleegkundige raak dikwels in etiese dilemmas betrokke ten opsigte van die hantering van die MIV-positiewe persoon by die werkplek deurdat die belange van die MIV-positiewe persoon botsend is met die belange van die werkgewer. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

The [4Fe-4S](2+) cluster in reconstituted biotin synthase binds S-adenosyl-L-methionine.

Science.gov (United States)

Cosper, Michele Mader; Jameson, Guy N L; Davydov, Roman; Eidsness, Marly K; Hoffman, Brian M; Huynh, Boi Hanh; Johnson, Michael K

2002-11-27

The combination of resonance Raman, electron paramagnetic resonance and Mössbauer spectroscopies has been used to investigate the effect of S-adenosyl-l-methionine (SAM) on the spectroscopic properties of the [4Fe-4S]2+ cluster in biotin synthase. The results indicate that SAM interacts directly at a unique iron site of the [4Fe-4S]2+ cluster in BioB and support the hypothesis of a common inner-sphere mechanism for the reductive cleavage of SAM in the radical SAM family of Fe-S enzymes.

The 4p-5d, 6d and 4p-6s, 7s transitions of Mo IX

International Nuclear Information System (INIS)

Khatoon, S.; Chaghtai, M.S.Z.; Rahimullah, K.

1979-01-01

The transitions 4p-5d, 6d and 4p-6s, 7s have been studied for the first time in Mo IX. The authors have identified 42 4p-5d, 36 4p-6d, 22 4p-6s and 22 4p-7s transitions, establishing 16 4p 3 5d, 14 4p 3 6d and all the ten 4p 3 6s, 7s levels of the spectrum concerned. The ionization energy is estimated to be (1 323 700 +- 700)cm -1 or (164.11 +- 0.09)eV. The spectrum was recorded in sliding and open spark discharges with a 5 m grazing incidence spectrograph of Lund University (Sweden) from about 40 A to 440 A. (Auth.)

Pearl Harbor: A Failure for Baseball?

Science.gov (United States)

Crepeau, Richard C.

The history of sports is closely tied to the larger history of the society in which they are played. Baseball in the United States in the 1920's and l930's assumed a major role in spreading the ideals of fair play, sportsmanship, and democracy to the Far East, with tours by amateur athletes and professionals such as Lou Gehrig and Babe Ruth. Even…

Preparation, properties and anticancer effects of mixed As4S4/ZnS nanoparticles capped by Poloxamer 407

International Nuclear Information System (INIS)

Bujňáková, Z.; Baláž, M.; Zdurienčíková, M.; Sedlák, J.; Čaplovičová, M.; Čaplovič, Ľ.; Dutková, E.; Zorkovská, A.; Turianicová, E.; Baláž, P.; Shpotyuk, O.

2017-01-01

Arsenic sulfide compounds have a long history of application in a traditional medicine. In recent years, realgar has been studied as a promising drug in cancer treatment. In this study, the arsenic sulfide (As 4 S 4 ) nanoparticles combined with zinc sulfide (ZnS) ones in different molar ratio have been prepared by a simple mechanochemical route in a planetary mill. The successful synthesis and structural properties were confirmed and followed via X-ray diffraction and high-resolution transmission electron microscopy measurements. The morphology of the particles was studied via scanning electron microscopy and transmission electron microscopy methods and the presence of nanocrystallites was verified. For biological tests, the prepared As 4 S 4 /ZnS nanoparticles were further milled in a circulation mill in a water solution of Poloxamer 407 (0.5 wt%), in order to cover the particles with this biocompatible copolymer and to obtain stable nanosuspensions with unimodal distribution. The average size of the particles in the nanosuspensions (~ 120 nm) was determined by photon cross-correlation spectroscopy method. Stability of the nanosuspensions was determined via particle size distribution and zeta potential measurements, confirming no physico-chemical changes for several months. Interestingly, with the increasing amount of ZnS in the sample, the stability was improved. The anti-cancer effects were tested on two melanoma cell lines, A375 and Bowes, with promising results, confirming increased efficiency of the samples containing both As 4 S 4 and ZnS nanocrystals. - Highlights: • Mixed As 4 S 4 /ZnS nanoparticles were prepared by dry milling in the first stage • Stable nanosuspensions of As 4 S 4 /ZnS nanoparticles capped by Poloxamer 407 were prepared by wet milling in the second stage • ZnS in the samples is beneficial: higher values of S A , stability, solubility and anticancer activity were improved

Improved GaSb surfaces using a (NH4)2S/(NH4)2S04 solution

International Nuclear Information System (INIS)

Murape, D.M.; Eassa, N.; Nyamhere, C.; Neethling, J.H.; Betz, R.; Coetsee, E.; Swart, H.C.; Botha, J.R.; Venter, A.

2012-01-01

Bulk (1 0 0) n-GaSb surfaces have been treated with a sulphur based solution ((NH 4 ) 2 S/(NH 4 ) 2 SO 4 ) to which sulphur has been added, not previously reported for the passivation of GaSb surfaces. Au/n-GaSb Schottky barrier diodes (SBDs) fabricated on the treated material show significant improvement compared to that of the similar SBDs on the as-received material as evidenced by the lower ideality factor (n), higher barrier height (φ b ) and lower contact resistance obtained. Additionally, the reverse leakage current, although not saturating, has been reduced by almost an order of magnitude at −0.2 V. The sample surfaces were studied by scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS). The native oxide, Sb–O, present on the as-received material is effectively removed on treating with ([(NH 4 ) 2 S/(NH 4 ) 2 SO 4 ]+S) and (NH 4 ) 2 S. Analysis of the as-received surface by XPS, prior to and after argon sputtering, suggests that the native oxide layer is ≤8.5 nm.

Synthesis and structure of Li{sub 4}GeS{sub 4}

Energy Technology Data Exchange (ETDEWEB)

Matsushita, Y [National Inst. of Materials and Chemical Research, Tsukuba (Japan). High Pressure Lab.; Kanatzidis, M G [Michigan State Univ., East Lansing, MI (United States). Dept. of Chemistry

1998-01-01

The compound Li{sub 4}GeS{sub 4} has been prepared as transparent, light yellow moisture-sensitive crystals. Li{sub 4}GeS{sub 4} belongs to the space group Pnma with a = 14.107(6) A, b = 7.770(3) A and c = 6.162(2) A. The crystal structure was solved by direct-methods. The final R and R{sub w}-values are 1.85 and 1.65% for 866 observed reflections. The Li{sub 4}GeS{sub 4} structure has three crystallographically independent lithium sites and one germanium site. The lithium atoms adopt two different coordination types. The Li1 atom is coordinated to five sulfur atoms in a square pyramidal geometry, while the Li2 and Li3 atoms have distorted tetrahedral coordination. The Ge atom is tetrahedrally coordinated by four sulfur atoms and is found as [GeS{sub 4}]{sup 4-} units. The anisotropic three-dimensional crystal structure of Li{sub 4}GeS{sub 4} is described. (orig.) 57 refs.

Syntheses, structural variants and characterization of AInM′S4 (A=alkali metals, Tl; M′ = Ge, Sn) compounds; facile ion-exchange reactions of layered NaInSnS4 and KInSnS4 compounds

International Nuclear Information System (INIS)

Yohannan, Jinu P.; Vidyasagar, Kanamaluru

2016-01-01

Ten AInM′S 4 (A=alkali metals, Tl; M′= Ge, Sn) compounds with diverse structure types have been synthesized and characterized by single crystal and powder X-ray diffraction and a variety of spectroscopic methods. They are wide band gap semiconductors. KInGeS 4 (1-β), RbInGeS 4 (2), CsInGeS 4 (3-β), TlInGeS 4 (4-β), RbInSnS 4 (8-β) and CsInSnS 4 (9) compounds with three-dimensional BaGa 2 S 4 structure and CsInGeS 4 (3-α) and TlInGeS 4 (4-α) compounds with a layered TlInSiS 4 structure have tetrahedral [InM′S 4 ] − frameworks. On the other hand, LiInSnS 4 (5) with spinel structure and NaInSnS 4 (6), KInSnS 4 (7), RbInSnS 4 (8-α) and TlInSnS 4 (10) compounds with layered structure have octahedral [InM′S 4 ] − frameworks. NaInSnS 4 (6) and KInSnS 4 (7) compounds undergo facile topotactic ion-exchange, at room temperature, with various mono-, di- and tri-valent cations in aqueous medium to give rise to metastable layered phases. - Graphical abstract: NaInSnS 4 and KInSnS 4 compounds undergo, in aqueous medium at room temperature, facile topotactic ion-exchange with mono, di and trivalent cations. Display Omitted - Highlights: • Ten AInM′S 4 compounds with diverse structure types were synthesized. • They are wide band gap semiconductors. • NaInSnS 4 and KInSnS 4 compounds undergo facile topotactic ion-exchange at room temperature.

(1S,3S,4S-tert-Butyl N-[1-benzyl-3-hydroxy-5-phenyl-4-(picolinamidopentyl]carbamate

Directory of Open Access Journals (Sweden)

Jian-Feng Zheng

2008-07-01

Full Text Available The title compound, C29H35N3O4, was obtained by the reaction of (2S,4S,5S-tert-butyl N-(4-amino-1-benzyl-3-hydroxy-5-phenylpentylcarbamate and picolinic acid using oxalyl chloride as a chlorinating reagent to activate the carboxyl group. In the crystal structure there are two molecules in the asymmetric unit, which are aligned edge-to-face. In one molecule, the pyridyl ring forms a dihedral angle of 22.0 (1° with the phenyl ring of the terminal benzyl group and 14.3 (1° with the other phenyl ring; in the other molecule, the corresponding angles are 12.1 (1 and 10.6 (1°, respectively. The packing is stabilized by intermolecular hydrogen bonds and C—H...π interactions.

Werken aan een veilige delta

NARCIS (Netherlands)

Jonkman, S.N.; Kok, M.

2012-01-01

De recente overstromingen in het buitenland (New Orleans, Thailand, Japan en New York) laten zien hoe groot de maatschappelijke ontwrichting na een overstroming is en wat het belang van een goed waterkeringssysteem is. Hoewel Nederland één van de best beveiligde delta’s in de wereld is, voldoet een

Social Democratic parties as buffers against the extreme right : the case of Belgium

NARCIS (Netherlands)

Coffé, Hilde

2008-01-01

While the Vlaams Blok (currently Vlaams Belang) became one of the most successful and electorally durable extreme-right parties in Europe in the 1990s, the francophone Front National has yet to achieve a stable basis of support. We argue that an important reason for this divergence has been the

Laser spectroscopy of the 4s4p(3) P-2-4s3d(1) D-2 transition on magnetically trapped calcium atoms

NARCIS (Netherlands)

Dammalapati, U.; Norris, I.; Burrows, C.; Riis, E.

2011-01-01

Laser excitation of the 4s4p(3) P-2-4s3d(1) D-2 transition in atomic calcium has been observed and the wavelength determined to 1530.5298(6) nm. The metastable 4s4p(3) P-2 atoms were magnetically trapped in the quadrupole magnetic field of a magneto-optical trap. This state represents the only

EPA’s SPECIATE 4.4 Database:Development and Uses

Science.gov (United States)

SPECIATE is the U.S. Environmental Protection Agency's (EPA)repository of volatile organic gas and particulate matter (PM) speciation profiles for air pollution sources. EPA released SPECIATE 4.4 in early 2014 and, in total, the SPECIATE 4.4 database includes 5,728 PM, VOC, total...

Design, Synthesis and Antitumor Activity of Novel 4-Methyl-(3'S,4'S-cis-khellactone Derivatives

Directory of Open Access Journals (Sweden)

Taigang Liang

2013-04-01

Full Text Available An asymmetric synthesis of a series of novel 4-methyl-(3'S,4'S-cis-khellactone derivatives 3a–o is reported for the first time. Their structures were confirmed by 1H-NMR, 13C-NMR and MS. Their cytotoxic activity was evaluated by the MTT assay against three selected human cancer cell lines: HEPG-2 (human liver carcinoma, SGC-7901 (human gastric carcinoma, LS174T (human colon carcinoma. Some compounds showed high inhibitory activity against these human cancer cell lines. Among them, compound 3a exhibited strong cytotoxicity, with IC50 values ranging from 8.51 to 29.65 μM. The results showed that 4-methyl-cis-khellactone derivatives with S,S configuration could be a potential antitumor agents.

Electronic properties of GaV 4 S 8

Indian Academy of Sciences (India)

... different in GaV4S8-1 and GaV4S8-2. This statement is strongly supported by the calculated bandwidth per cluster in GaV4S8 (∼0.342 eV in GaV4S8-1 and ∼0.374 eV in GaV4S8-2). A negative magnetoresistance (MR) is also found around 43 K in GaV4S8-2 at 6.0 T magnetic field associated with structural transition.

Improved GaSb surfaces using a (NH{sub 4}){sub 2}S/(NH{sub 4}){sub 2}S0{sub 4} solution

Energy Technology Data Exchange (ETDEWEB)

Murape, D.M., E-mail: Davison.Murape@live.nmmu.ac.za [Department of Physics, Nelson Mandela Metropolitan University, PO Box 77000, Port Elizabeth 6031 (South Africa); Eassa, N.; Nyamhere, C.; Neethling, J.H. [Department of Physics, Nelson Mandela Metropolitan University, PO Box 77000, Port Elizabeth 6031 (South Africa); Betz, R. [Department of Chemistry, Nelson Mandela Metropolitan University, PO Box 77000, Port Elizabeth 6031 (South Africa); Coetsee, E.; Swart, H.C. [Department of Physics, University of the Free State, PO Box 339, Bloemfontein 9300 (South Africa); Botha, J.R.; Venter, A. [Department of Physics, Nelson Mandela Metropolitan University, PO Box 77000, Port Elizabeth 6031 (South Africa)

2012-05-15

Bulk (1 0 0) n-GaSb surfaces have been treated with a sulphur based solution ((NH{sub 4}){sub 2}S/(NH{sub 4}){sub 2}SO{sub 4}) to which sulphur has been added, not previously reported for the passivation of GaSb surfaces. Au/n-GaSb Schottky barrier diodes (SBDs) fabricated on the treated material show significant improvement compared to that of the similar SBDs on the as-received material as evidenced by the lower ideality factor (n), higher barrier height ({phi}{sub b}) and lower contact resistance obtained. Additionally, the reverse leakage current, although not saturating, has been reduced by almost an order of magnitude at -0.2 V. The sample surfaces were studied by scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS). The native oxide, Sb-O, present on the as-received material is effectively removed on treating with ([(NH{sub 4}){sub 2}S/(NH{sub 4}){sub 2}SO{sub 4}]+S) and (NH{sub 4}){sub 2}S. Analysis of the as-received surface by XPS, prior to and after argon sputtering, suggests that the native oxide layer is {<=}8.5 nm.

NMR of proteins (4Fe-4S): structural properties and intramolecular electron transfer; RMN de proteines (4Fe-4S): proprietes structurales et transfert electronique intramoleculaire

Energy Technology Data Exchange (ETDEWEB)

Huber, J G

1996-10-17

NMR started to be applied to Fe-S proteins in the seventies. Its use has recently been enlarged as the problems arising from the paramagnetic polymetallic clusters ware overcome. Applications to [4Fe-4S] are presented herein. The information derived thereof deepens the understanding of the redox properties of these proteins which play a central role in the metabolism of bacterial cells. The secondary structure elements and the overall folding of Chromatium vinosum ferredoxin (Cv Fd) in solution have been established by NMR. The unique features of this sequence have been shown to fold as an {alpha} helix at the C-terminus and as a loop between two cysteines ligand of one cluster: these two parts localize in close proximity from one another. The interaction between nuclear and electronic spins is a source of additional structural information for (4Fe-AS] proteins. The conformation of the cysteine-ligands, as revealed by the Fe-(S{sub {gamma}}-C{sub {beta}}-H{sub {beta}})Cys dihedral angles, is related to the chemical shifts of the signals associated with the protons of these residues. The longitudinal relaxation times of the protons depend on their distance to the cluster. A quantitative relationship has been established and used to show that the solution structure of the high-potential ferredoxin from Cv differs significantly from the crystal structure around Phe-48. Both parameters (chemical shifts and longitudinal relaxation times) give also insight into the electronic and magnetic properties of the [4Fe-4S] clusters. The rate of intramolecular electron transfer between the two [4FE-4S] clusters of ferredoxins has been measured by NMR. It is far slower in the case of Cv Fd than for shorter ferredoxins. The difference may be associated with changes in the magnetic and/or electronic properties of one cluster. The strong paramagnetism of the [4Fe-4S] clusters, which originally limited the applicability of NMR to proteins containing these cofactors, has been proven

Biotransformation of (-)-(1R,4S)-Menthone and (+)-(1S,4R)-Menthone by the Common Cutworm Spodoptera litura Larvae.

Science.gov (United States)

Marumoto, Shinsuke; Okuno, Yoshiharu; Hagiwara, Yuki; Miyazawa, Mitsuo

2017-08-01

Using biotransformation as a biocatalytic process has the advantage of being able to proceed under mild conditions and with high regio- and enantioselectivity. This study investigated the biotransformation of (-)-(1R,4S)-menthone (1) and (+)-(1S,4R)-menthone (2) by Spodoptera litura larvae. Compound 1 was converted to (-)-(1R,4S)-7-hydroxymenthone (1-1), (+)-(1R,3S,4S)-7-hydroxyneomenthol (1-2) and (-)-(1R,4S,8R)-p-menth-3-one-9-oic acid (1-3). The metabolism of substrate 2 generated three enantiomers of the above metabolites, designated as 2-1 to 2-3, respectively. The C-9 position of (-)-menthone and (+)-menthone was oxidized to carboxylic acid by S. litura, which is a metabolic pathway not observed in any other example of biocatalysis.

The space of harmonic maps of S2 into S4

International Nuclear Information System (INIS)

Loo, B.

1989-05-01

Every branched superminimal surface of area 4πd in S 4 is shown to arise from a pair of meromorphic functions (f 1 ,f 2 ) of bidegree (d,d) such that f 1 and f 2 have the same ramification divisor. Conditions under which branched superminimal surfaces can be generated from such pairs of functions are derived. For each d ≥ 1 the space of harmonic maps (i.e branched superminimal immersions) of S 2 into S 4 of harmonic degree d is shown to be a connected space of complex dimension 2d+4. (author). 18 refs

Preparation, properties and anticancer effects of mixed As{sub 4}S{sub 4}/ZnS nanoparticles capped by Poloxamer 407

Energy Technology Data Exchange (ETDEWEB)

Bujňáková, Z., E-mail: bujnakova@saske.sk [Institute of Geotechnics, Slovak Academy of Sciences, Watsonova 45, 04001 Košice (Slovakia); Baláž, M. [Institute of Geotechnics, Slovak Academy of Sciences, Watsonova 45, 04001 Košice (Slovakia); Zdurienčíková, M.; Sedlák, J. [Cancer Research Institute, BMC Slovak Academy of Sciences, Dúbravská 9, 84505 Bratislava (Slovakia); Čaplovičová, M. [STU Centre for Nanodiagnostics, Slovak University of Technology, Vazovova 5, 81243 Bratislava (Slovakia); Čaplovič, Ľ. [Faculty of Materials Science and Technology, Slovak University of Technology, Paulínska 16, 91724 Trnava (Slovakia); Dutková, E.; Zorkovská, A.; Turianicová, E.; Baláž, P. [Institute of Geotechnics, Slovak Academy of Sciences, Watsonova 45, 04001 Košice (Slovakia); Shpotyuk, O. [Scientific Research Company “Carat”, Stryjska 202, 79031 Lviv (Ukraine); Institute of Physics, Jan Dlugosz University, Armii Krajowej 13/15., 42200 Czestochowa (Poland); and others

2017-02-01

Arsenic sulfide compounds have a long history of application in a traditional medicine. In recent years, realgar has been studied as a promising drug in cancer treatment. In this study, the arsenic sulfide (As{sub 4}S{sub 4}) nanoparticles combined with zinc sulfide (ZnS) ones in different molar ratio have been prepared by a simple mechanochemical route in a planetary mill. The successful synthesis and structural properties were confirmed and followed via X-ray diffraction and high-resolution transmission electron microscopy measurements. The morphology of the particles was studied via scanning electron microscopy and transmission electron microscopy methods and the presence of nanocrystallites was verified. For biological tests, the prepared As{sub 4}S{sub 4}/ZnS nanoparticles were further milled in a circulation mill in a water solution of Poloxamer 407 (0.5 wt%), in order to cover the particles with this biocompatible copolymer and to obtain stable nanosuspensions with unimodal distribution. The average size of the particles in the nanosuspensions (~ 120 nm) was determined by photon cross-correlation spectroscopy method. Stability of the nanosuspensions was determined via particle size distribution and zeta potential measurements, confirming no physico-chemical changes for several months. Interestingly, with the increasing amount of ZnS in the sample, the stability was improved. The anti-cancer effects were tested on two melanoma cell lines, A375 and Bowes, with promising results, confirming increased efficiency of the samples containing both As{sub 4}S{sub 4} and ZnS nanocrystals. - Highlights: • Mixed As{sub 4}S{sub 4}/ZnS nanoparticles were prepared by dry milling in the first stage • Stable nanosuspensions of As{sub 4}S{sub 4}/ZnS nanoparticles capped by Poloxamer 407 were prepared by wet milling in the second stage • ZnS in the samples is beneficial: higher values of S{sub A}, stability, solubility and anticancer activity were improved.

Syntheses, structural variants and characterization of AInM′S{sub 4} (A=alkali metals, Tl; M′ = Ge, Sn) compounds; facile ion-exchange reactions of layered NaInSnS{sub 4} and KInSnS{sub 4} compounds

Energy Technology Data Exchange (ETDEWEB)

Yohannan, Jinu P.; Vidyasagar, Kanamaluru, E-mail: kvsagar@iitm.ac.in

2016-06-15

Ten AInM′S{sub 4} (A=alkali metals, Tl; M′= Ge, Sn) compounds with diverse structure types have been synthesized and characterized by single crystal and powder X-ray diffraction and a variety of spectroscopic methods. They are wide band gap semiconductors. KInGeS{sub 4}(1-β), RbInGeS{sub 4}(2), CsInGeS{sub 4}(3-β), TlInGeS{sub 4}(4-β), RbInSnS{sub 4}(8-β) and CsInSnS{sub 4}(9) compounds with three-dimensional BaGa{sub 2}S{sub 4} structure and CsInGeS{sub 4}(3-α) and TlInGeS{sub 4}(4-α) compounds with a layered TlInSiS{sub 4} structure have tetrahedral [InM′S{sub 4}]{sup −} frameworks. On the other hand, LiInSnS{sub 4}(5) with spinel structure and NaInSnS{sub 4}(6), KInSnS{sub 4}(7), RbInSnS{sub 4}(8-α) and TlInSnS{sub 4}(10) compounds with layered structure have octahedral [InM′S{sub 4}]{sup −} frameworks. NaInSnS{sub 4}(6) and KInSnS{sub 4}(7) compounds undergo facile topotactic ion-exchange, at room temperature, with various mono-, di- and tri-valent cations in aqueous medium to give rise to metastable layered phases. - Graphical abstract: NaInSnS{sub 4} and KInSnS{sub 4} compounds undergo, in aqueous medium at room temperature, facile topotactic ion-exchange with mono, di and trivalent cations. Display Omitted - Highlights: • Ten AInM′S{sub 4} compounds with diverse structure types were synthesized. • They are wide band gap semiconductors. • NaInSnS{sub 4} and KInSnS{sub 4} compounds undergo facile topotactic ion-exchange at room temperature.

Contribution of S4 segments and S4-S5 linkers to the low-voltage activation properties of T-type CaV3.3 channels.

Directory of Open Access Journals (Sweden)

Ana Laura Sanchez-Sandoval

Full Text Available Voltage-gated calcium channels contain four highly conserved transmembrane helices known as S4 segments that exhibit a positively charged residue every third position, and play the role of voltage sensing. Nonetheless, the activation range between high-voltage (HVA and low-voltage (LVA activated calcium channels is around 30-40 mV apart, despite the high level of amino acid similarity within their S4 segments. To investigate the contribution of S4 voltage sensors for the low-voltage activation characteristics of CaV3.3 channels we constructed chimeras by swapping S4 segments between this LVA channel and the HVA CaV1.2 channel. The substitution of S4 segment of Domain II in CaV3.3 by that of CaV1.2 (chimera IIS4C induced a ~35 mV shift in the voltage-dependence of activation towards positive potentials, showing an I-V curve that almost overlaps with that of CaV1.2 channel. This HVA behavior induced by IIS4C chimera was accompanied by a 2-fold decrease in the voltage-dependence of channel gating. The IVS4 segment had also a strong effect in the voltage sensing of activation, while substitution of segments IS4 and IIIS4 moved the activation curve of CaV3.3 to more negative potentials. Swapping of IIS4 voltage sensor influenced additional properties of this channel such as steady-state inactivation, current decay, and deactivation. Notably, Domain I voltage sensor played a major role in preventing CaV3.3 channels to inactivate from closed states at extreme hyperpolarized potentials. Finally, site-directed mutagenesis in the CaV3.3 channel revealed a partial contribution of the S4-S5 linker of Domain II to LVA behavior, with synergic effects observed in double and triple mutations. These findings indicate that IIS4 and, to a lesser degree IVS4, voltage sensors are crucial in determining the LVA properties of CaV3.3 channels, although the accomplishment of this function involves the participation of other structural elements like S4-S5 linkers.

Contribution of S4 segments and S4-S5 linkers to the low-voltage activation properties of T-type CaV3.3 channels

Science.gov (United States)

Sanchez-Sandoval, Ana Laura; Herrera Carrillo, Zazil; Díaz Velásquez, Clara Estela; Delgadillo, Dulce María; Rivera, Heriberto Manuel

2018-01-01

Voltage-gated calcium channels contain four highly conserved transmembrane helices known as S4 segments that exhibit a positively charged residue every third position, and play the role of voltage sensing. Nonetheless, the activation range between high-voltage (HVA) and low-voltage (LVA) activated calcium channels is around 30–40 mV apart, despite the high level of amino acid similarity within their S4 segments. To investigate the contribution of S4 voltage sensors for the low-voltage activation characteristics of CaV3.3 channels we constructed chimeras by swapping S4 segments between this LVA channel and the HVA CaV1.2 channel. The substitution of S4 segment of Domain II in CaV3.3 by that of CaV1.2 (chimera IIS4C) induced a ~35 mV shift in the voltage-dependence of activation towards positive potentials, showing an I-V curve that almost overlaps with that of CaV1.2 channel. This HVA behavior induced by IIS4C chimera was accompanied by a 2-fold decrease in the voltage-dependence of channel gating. The IVS4 segment had also a strong effect in the voltage sensing of activation, while substitution of segments IS4 and IIIS4 moved the activation curve of CaV3.3 to more negative potentials. Swapping of IIS4 voltage sensor influenced additional properties of this channel such as steady-state inactivation, current decay, and deactivation. Notably, Domain I voltage sensor played a major role in preventing CaV3.3 channels to inactivate from closed states at extreme hyperpolarized potentials. Finally, site-directed mutagenesis in the CaV3.3 channel revealed a partial contribution of the S4-S5 linker of Domain II to LVA behavior, with synergic effects observed in double and triple mutations. These findings indicate that IIS4 and, to a lesser degree IVS4, voltage sensors are crucial in determining the LVA properties of CaV3.3 channels, although the accomplishment of this function involves the participation of other structural elements like S4-S5 linkers. PMID:29474447

Contribution of S4 segments and S4-S5 linkers to the low-voltage activation properties of T-type CaV3.3 channels.

Science.gov (United States)

Sanchez-Sandoval, Ana Laura; Herrera Carrillo, Zazil; Díaz Velásquez, Clara Estela; Delgadillo, Dulce María; Rivera, Heriberto Manuel; Gomora, Juan Carlos

2018-01-01

Voltage-gated calcium channels contain four highly conserved transmembrane helices known as S4 segments that exhibit a positively charged residue every third position, and play the role of voltage sensing. Nonetheless, the activation range between high-voltage (HVA) and low-voltage (LVA) activated calcium channels is around 30-40 mV apart, despite the high level of amino acid similarity within their S4 segments. To investigate the contribution of S4 voltage sensors for the low-voltage activation characteristics of CaV3.3 channels we constructed chimeras by swapping S4 segments between this LVA channel and the HVA CaV1.2 channel. The substitution of S4 segment of Domain II in CaV3.3 by that of CaV1.2 (chimera IIS4C) induced a ~35 mV shift in the voltage-dependence of activation towards positive potentials, showing an I-V curve that almost overlaps with that of CaV1.2 channel. This HVA behavior induced by IIS4C chimera was accompanied by a 2-fold decrease in the voltage-dependence of channel gating. The IVS4 segment had also a strong effect in the voltage sensing of activation, while substitution of segments IS4 and IIIS4 moved the activation curve of CaV3.3 to more negative potentials. Swapping of IIS4 voltage sensor influenced additional properties of this channel such as steady-state inactivation, current decay, and deactivation. Notably, Domain I voltage sensor played a major role in preventing CaV3.3 channels to inactivate from closed states at extreme hyperpolarized potentials. Finally, site-directed mutagenesis in the CaV3.3 channel revealed a partial contribution of the S4-S5 linker of Domain II to LVA behavior, with synergic effects observed in double and triple mutations. These findings indicate that IIS4 and, to a lesser degree IVS4, voltage sensors are crucial in determining the LVA properties of CaV3.3 channels, although the accomplishment of this function involves the participation of other structural elements like S4-S5 linkers.

irn'>8 H7H7 v;'nr''3 “"iO? nin) inpn 9

African Journals Online (AJOL)

... kyk Scoralik (1989:62-68). Vergelyk ook die belang rikste kommentare ad hoc waar allerlei tekskritiese veranderinge voorgestel word in 'n poging om die interpretasieprobleem op te los. Vergelyk ook Eaton. (1968:555-556) in dié verband. 22. Jeremias (1987:114), wat 'n breuk by vers 4 bemerk, beskou die wow egter as.

Preparation, properties and anticancer effects of mixed As4S4/ZnS nanoparticles capped by Poloxamer 407.

Science.gov (United States)

Bujňáková, Z; Baláž, M; Zdurienčíková, M; Sedlák, J; Čaplovičová, M; Čaplovič, Ľ; Dutková, E; Zorkovská, A; Turianicová, E; Baláž, P; Shpotyuk, O; Andrejko, S

2017-02-01

Arsenic sulfide compounds have a long history of application in a traditional medicine. In recent years, realgar has been studied as a promising drug in cancer treatment. In this study, the arsenic sulfide (As 4 S 4 ) nanoparticles combined with zinc sulfide (ZnS) ones in different molar ratio have been prepared by a simple mechanochemical route in a planetary mill. The successful synthesis and structural properties were confirmed and followed via X-ray diffraction and high-resolution transmission electron microscopy measurements. The morphology of the particles was studied via scanning electron microscopy and transmission electron microscopy methods and the presence of nanocrystallites was verified. For biological tests, the prepared As 4 S 4 /ZnS nanoparticles were further milled in a circulation mill in a water solution of Poloxamer 407 (0.5wt%), in order to cover the particles with this biocompatible copolymer and to obtain stable nanosuspensions with unimodal distribution. The average size of the particles in the nanosuspensions (~120nm) was determined by photon cross-correlation spectroscopy method. Stability of the nanosuspensions was determined via particle size distribution and zeta potential measurements, confirming no physico-chemical changes for several months. Interestingly, with the increasing amount of ZnS in the sample, the stability was improved. The anti-cancer effects were tested on two melanoma cell lines, A375 and Bowes, with promising results, confirming increased efficiency of the samples containing both As 4 S 4 and ZnS nanocrystals. Copyright © 2016 Elsevier B.V. All rights reserved.

Nanostructurization effects in PVP-stabilized tetra-arsenic tetra-sulfide As_4S_4 nanocomposites

International Nuclear Information System (INIS)

Shpotyuk, O.; Bujňáková, Z.; Baláž, P.; Ingram, A.; Demchenko, P.; Kovalskiy, A.; Vlcek, M.; Shpotyuk, Ya.; Cebulski, J.; Dziedzic, A.

2017-01-01

Nanostructurization in three types of tetra-arsenic tetra-sulfide As_4S_4 polymorphs composed by (1) preferential β-As_4S_4, (2) realgar α-As_4S_4 and (3) admixture of As_4S_4 in the form of β-realgar, pararealgar and intermediate χ-phase subjected to mechanochemical ball milling in a water solution of polyvinylpyrrolidone (PVP) are characterized with multiexperimental structure-sensitive probes. Void structure of pelletized As_4S_4-PVP nanocomposites is probed by positron annihilation lifetime spectroscopy complemented with atomic-sensitive techniques such as X-ray powder diffraction, Raman scattering and scanning electron microscopy with energy-dispersive X-ray spectroscopy. Appearance of arsenolite As_2O_3 crystallites is character for all As_4S_4 polymorphs affected by wet milling. Positron annihilation lifetime data considered in terms of substitution positron-positronium trapping confirm complicated nature of nanocomposites. Modified x3-x2-coupling decomposition algorithm developed in addition to unconstrained x3-term fitting procedure is applied to parameterize annihilation channels in these nanocomposites. Interfacial free-volume voids between neighboring nanoparticles in PVP environment are defined as most favorable trapping sites, they being rather loosely composed by As_4S_4 crystallites in full respect to variety of crystallographic polymorphs used for milling. Detected annihilation channels are ascribed preferentially to intrinsic free-volume voids insensitive to trapping states at the surface of oxidized nanocomposites. - Highlights: • PVP-stabilized tetra-arsenic tetra-sulfide nanocomposites prepared by wet milling. • As_4S_4-PVP composites by complementary atomic-specific and deficient structure probes. • Surface oxidation due to crystalline arsenolite As_2O_3 under wet milling. • Free-volume structure of PVP-stabilized As_4S_4 nanocomposites by PAL spectroscopy. • x3-x2-coupling decomposition algorithm to treat PAL data for As_4S_4

Structural interactions between lipids, water and S1-S4 voltage-sensing domains.

Science.gov (United States)

Krepkiy, Dmitriy; Gawrisch, Klaus; Swartz, Kenton J

2012-11-02

Membrane proteins serve crucial signaling and transport functions, yet relatively little is known about their structures in membrane environments or how lipids interact with these proteins. For voltage-activated ion channels, X-ray structures suggest that the mobile voltage-sensing S4 helix would be exposed to the membrane, and functional studies reveal that lipid modification can profoundly alter channel activity. Here, we use solid-state NMR to investigate structural interactions of lipids and water with S1-S4 voltage-sensing domains and to explore whether lipids influence the structure of the protein. Our results demonstrate that S1-S4 domains exhibit extensive interactions with lipids and that these domains are heavily hydrated when embedded in a membrane. We also find evidence for preferential interactions of anionic lipids with S1-S4 domains and that these interactions have lifetimes on the timescale of ≤ 10(-3)s. Arg residues within S1-S4 domains are well hydrated and are positioned in close proximity to lipids, exhibiting local interactions with both lipid headgroups and acyl chains. Comparative studies with a positively charged lipid lacking a phosphodiester group reveal that this lipid modification has only modest effects on the structure and hydration of S1-S4 domains. Taken together, our results demonstrate that Arg residues in S1-S4 voltage-sensing domains reside in close proximity to the hydrophobic interior of the membrane yet are well hydrated, a requirement for carrying charge and driving protein motions in response to changes in membrane voltage. Published by Elsevier Ltd.

CMB-S4 Technology Book, First Edition

Energy Technology Data Exchange (ETDEWEB)

Abitbol, Maximilian H. [Columbia Univ., New York, NY (United States); et al.

2017-06-08

CMB-S4 is a proposed experiment to map the polarization of the Cosmic Microwave Background (CMB) to nearly the cosmic variance limit for the angular scales that are accessible from the ground. The science goals and capabilities of CMB-S4 in illuminating cosmic inflation, measuring the sum of neutrino masses, searching for relativistic relics in the early universe, characterizing dark energy and dark matter, and mapping the matter distribution in the universe have been described in the CMB-S4 Science Book. This Technology Book is a companion volume to the Science Book. The ambitious science goals of the proposed "Stage-IV" CMB-S4 will require a step forward in experimental capability from the current Stage-III experiments. To guide this process, the community summarized the current state of the technology and identify R&D efforts necessary to advance it for possible use in CMB-S4. The book focused on the technical challenges in four broad areas: Telescope Design; Receiver Optics; Focal-Plane Optical Coupling; and Focal-Plane Sensor and Readout.

Future classics / Priit Kruus

Index Scriptorium Estoniae

Kruus, Priit, 1981-

2005-01-01

Sisust: 1.1 Kõusaar - protagonist of a bestseller ; 1.2 Henno, a positive double ; 1.3 Angst filter Jürgen Rooste 1.4 Child-like Wimberg ; 2.1 The Estonian Finnegans Wake : [Berk Vaher's Lugulaul] ; 2.2 Agent Smith : [Mihkel Samarüütel] ; 2.3 A saviour against his will : [Mehis Heinsaar] ; 2.4 Flight : [Heiti Kender] ; 3.1 Viiding's hate and Keil's pain ; 3.2 Kind hearted nerd and beautiful babe : [Jan Kaus, Kerttu Rakke

Treatment for GaSb surfaces using a sulphur blended (NH4)2S/(NH4)2SO4 solution

International Nuclear Information System (INIS)

Murape, D.M.; Eassa, N.; Neethling, J.H.; Betz, R.; Coetsee, E.; Swart, H.C.; Botha, J.R.; Venter, A.

2012-01-01

A sulphur based chemical, [(NH 4 ) 2 S/(NH 4 ) 2 SO 4 ] to which S has been added, not previously reported for the treatment of (1 0 0) n-GaSb surfaces, is introduced and benchmarked against the commonly used passivants Na 2 S·9H 2 O and (NH 4 ) 2 S. The surfaces of the treated material were studied by scanning electron microscopy (SEM), Auger electron spectroscopy (AES) and X-ray photoelectron spectroscopy (XPS). It has been found that the native oxides present on the GaSb surface are more effectively removed when treated with ([(NH 4 ) 2 S/(NH 4 ) 2 SO 4 ] + S) than with (NH 4 ) 2 S or Na 2 S·9H 2 O, as evidenced by the ratio of the O 506eV to Sb 457eV AES peaks. XPS results reveal that Sb 2 S 3 /Sb 2 S 5 “replaces” Sb 2 O 3 /Sb 2 O 5 , suggesting that sulphur atoms substitute oxygen atoms in Sb 2 O 3 /Sb 2 O 5 to form Sb-S. It seems sulphurization only partially removes Ga 2 O 3 . Treatment with ([(NH 4 ) 2 S/(NH 4 ) 2 SO 4 ] + S) also results in a noteworthy improvement in the current-voltage (I-V) characteristics of Au/n-GaSb Schottky contacts compared to those fabricated on as-received material.

The radical cations of sulphur (S8sup(.+)) and tetrasulphur tetranitride (S4N4sup(.+)): a radiation-electron spin resonance study

International Nuclear Information System (INIS)

Chandra, Harish; Ramakrishna Rao, D.N.; Symons, M.C.R.

1987-01-01

Exposure of dilute solutions of S 8 and S 4 N 4 in trichlorofluoromethane to 60 Co γ-rays at 77 K gave the corresponding radical cations. Enrichment (99%) with 33 S gave greatly broadened electron spin resonance x and y features, with A( 33 S) approx. = + - 4 G, where A is the first formed species from sulfur. The z features showed a clear central line flanked by others with Asub(z) approx. = 28 G. The results suggest the presence of two equally coupled sulphur atoms. On annealing, species (A) changes irreversibly into species (B),possibly, S 8 radical + in a relaxed form in which two opposite atoms have formed a weak three-electron bond. A clear spectrum was produced from S 4 N 4 which showed little g-value variation and no evidence for 14 N splitting. It is concluded that the S 4 N 4 radical + cation has a relatively isolated semi-occupied molecular orbital, with low spin density on nitrogen. (author)

Mean life of the 2p4(1S)3s 2S state in fluorine

International Nuclear Information System (INIS)

Cheng, K.T.; Chen, M.H.

1985-01-01

In this work, we calculate the radiationless as well as the radiative decay rates for the 2p 4 ( 1 S)3s 2 S state. For comparison purposes, we also make similar calculations for the 2p 4 ( 1 D)4s 2 D state. Our calculation is based on the multi-configuration Dirac-Fock (MCDF) method. As spin-orbit interaction is built in, this method is capable of studying LS forbidden Auger transitions. Details of the Auger transition calculations have been given before. 9 refs

Secreted Frizzled related protein-4 (sFRP4) promotes epidermal differentiation and apoptosis

International Nuclear Information System (INIS)

Maganga, Richard; Giles, Natalie; Adcroft, Katharine; Unni, Ambili; Keeney, Diane; Wood, Fiona; Fear, Mark; Dharmarajan, Arunasalam

2008-01-01

The skin provides vital protection from infection and dehydration. Maintenance of the skin is through a constant program of proliferation, differentiation and apoptosis of epidermal cells, whereby proliferating cells in the basal layer differentiating to form the keratinized, anucleated stratum corneum. The WNT signalling pathway is known to be important in the skin. WNT signalling has been shown to be important both in epidermal development and in the maintenance and cycling of hair follicles and epidermal stem cells. However, the precise role for this pathway in epidermal differentiation remains unknown. We investigated the role of the WNT signalling inhibitor sFRP4 in epidermal differentiation. sFRP4 is expressed in both normal skin and keratinocytes in culture. Expression of sFRP4 mRNA and protein increases with keratinocyte differentiation and apoptosis, whilst exposure of keratinocytes to exogenous sFRP4 promotes apoptosis and expression of the terminal differentiation marker Involucrin. These data suggest sFRP4 promotes epidermal differentiation.

Super Bitches and Action Babes

DEFF Research Database (Denmark)

Schubart, Rikke

An analysis of the female hero in popular film genres such as actionfilms, war films, wip-films, rape-revenge dramas, science fiction from 1970-2006. Mostly American films but with chapters on Michelle Yeoh and Meiko Kaji.......An analysis of the female hero in popular film genres such as actionfilms, war films, wip-films, rape-revenge dramas, science fiction from 1970-2006. Mostly American films but with chapters on Michelle Yeoh and Meiko Kaji....

Tussenrapportage Validatie Onderwijsvernieuwingen (Validation Assistant in Instructional Design)

Science.gov (United States)

2007-05-01

validatie onderwij svemieuwingen D)atum mei 2007 Auteur (s) drs. J.P. van Meer drs. G,J. Veldhuis dr. M.L. van Ernmerik M.G. van Schaik Rubricering...als doel om nog beter is het van belang dat het maken van keuzes Auteur (s) passende adviezen te kunnen genereren. binnen een moeilijk grijpbaar...benaderd door de theorie achter de onderwijsconcepten te toetsen aan het oordeel van de expert. Er zijn echter beperkingen in deze opzet denkbaar die

S1 constrains S4 in the voltage sensor domain of Kv7.1 K+ channels.

Directory of Open Access Journals (Sweden)

Yoni Haitin

Full Text Available Voltage-gated K(+ channels comprise a central pore enclosed by four voltage-sensing domains (VSDs. While movement of the S4 helix is known to couple to channel gate opening and closing, the nature of S4 motion is unclear. Here, we substituted S4 residues of Kv7.1 channels by cysteine and recorded whole-cell mutant channel currents in Xenopus oocytes using the two-electrode voltage-clamp technique. In the closed state, disulfide and metal bridges constrain residue S225 (S4 nearby C136 (S1 within the same VSD. In the open state, two neighboring I227 (S4 are constrained at proximity while residue R228 (S4 is confined close to C136 (S1 of an adjacent VSD. Structural modeling predicts that in the closed to open transition, an axial rotation (approximately 190 degrees and outward translation of S4 (approximately 12 A is accompanied by VSD rocking. This large sensor motion changes the intra-VSD S1-S4 interaction to an inter-VSD S1-S4 interaction. These constraints provide a ground for cooperative subunit interactions and suggest a key role of the S1 segment in steering S4 motion during Kv7.1 gating.

The 4s- and 4p- XPS spectra of Xe, XeF2 and XeF4

International Nuclear Information System (INIS)

Ohno, Masahide

2003-01-01

The 4s- and 4p- XPS spectra of Xe gas, XeF 2 molecule and XeF 4 molecule are calculated by an ab-initio atomic many-body theory. The 4s-peak and the prominent '4p'-peak are predicted well by the present theory. In XeF 2 and XeF 4 the spectral lines observed below the 4d-double ionization threshold are the 4d -2 4f multiplet states strongly perturbed by the interaction with the initial 4p 1/2 -hole state. They are very similar to the spectral lines which emerge with an increase in atomic number (e.g. Ba)

Supplemental Table S4.xls

Indian Academy of Sciences (India)

143, AT3G05200.1, 8262, I, 0.6, 259312_at, ATL6 (Arabidopsis T?xicos en Levadura 6); protein binding / zinc ion binding. 144, LOC_Os08g37760.1, 8262, D, -1.07, Os.17554.1.S1_at, zinc finger, C3HC4 type family protein, expressed. 145, AT5G27420.1, 8262, D, -0.95, 246777_at, zinc finger (C3HC4-type RING finger) ...

A theoretical survey of 4s-4p and 4p-4d transitions in nickel-like ions through Sn XXIII

International Nuclear Information System (INIS)

Wyart, J.F.

1987-01-01

The predictions of 4s-4p and 4p-4d transitions derived from Slater-Condon type calculations of 3d 9 4s, -4p and -4d configurations in the sequence Zn III-Se VII have been recently confirmed experimentally through Mo XV. These new data are used here to refine the predictions in the sequence Mo XV-Sn XXIII. The radial parameters involved in the three configurations are determined in generalized least-squares fits using all known levels in the sequence. (orig.)

Integrable systems from membranes on AdS4 x S7

International Nuclear Information System (INIS)

Bozhilov, P.

2008-01-01

We describe how Neumann and Neumann-Rosochatius type integrable systems, as well as the continuous limit of the SU(2) integrable spin chain, can be obtained from membranes on AdS 4 x S 7 background, in the framework of AdS/CFT correspondence. (Abstract Copyright [2008], Wiley Periodicals, Inc.)

G4S fuajee ruumiinstallatsioon = G4S lobby spatial installation / Ville Lausmäe

Index Scriptorium Estoniae

Lausmäe, Ville, 1981-

2013-01-01

Turvafirma G4S büroohoone (Paldiski mnt 80, Tallinn) fuajee sisekujundusest. Autorid: Ville Lausmäe, Kadi Karmann (sisearhitektuuribüroo VLS). Kultuuriministeeriumi kunstinõuniku Maria-Kristiina Soomre arvamus. Lühidalt sisearhitektuuribüroost VLS

Enhanced visible-light photocatalytic decomposition of 2,4-dichlorophenoxyacetic acid over ZnIn_2S_4/g-C_3N_4 photocatalyst

International Nuclear Information System (INIS)

Qiu, Pengxiang; Yao, Jinhua; Chen, Huan; Jiang, Fang; Xie, Xianchuan

2016-01-01

Highlights: • A novel flower-on-sheet ZnIn_2S_4/g-C_3N_4 nanocomposite was synthesized. • ZnIn_2S_4/g-C_3N_4 showed high visible light catalytic activity for 2,4-D degradation. • The photocatalytic degradation pathway of 2,4-D was investigated. - Abstract: ZnIn_2S_4/g-C_3N_4 heterojunction photocatalyst was successfully synthesized via a simple hydrothermal method and applied to visible-light photocatalytic decomposition of 2,4-dichlorophenoxyacetic acid (2,4-D) from aqueous phase. The flower-like ZnIn_2S_4 particles were dispersed on the surface of g-C_3N_4 nanosheets in the ZnIn_2S_4/g-C_3N_4 composite. The composite showed higher separation rate of electron-hole pairs as compared to ZnIn_2S_4 and g-C_3N_4. Consequently, the ZnIn_2S_4/g-C_3N_4 composite exhibited enhanced visible light photocatalytic decomposition efficiency of 2,4-D, within 20% ZnIn_2S_4/g-C_3N_4 composite owning the highest photocatalytic efficiency and initial rate. The initial rates of 2,4-D degradation on g-C_3N_4, ZnIn_2S_4, and 20% ZnIn_2S_4/g-C_3N_4 were 1.23, 0.57 and 3.69 mmol/(g_c_a_t h), respectively. The h"+ and O_2"·"− were found to be the dominant active species for 2,4-D decomposition. The photocatalytic degradation pathways of 2,4-D by ZnIn_2S_4/g-C_3N_4 under visible light irradiation were explored. The ZnIn_2S_4/g-C_3N_4 composite displayed high photostability in recycling tests, reflecting its promising potential as an effective visible light photocatalyst for 2,4-D treatment.

Significance of the S100A4 protein in psoriasis

DEFF Research Database (Denmark)

Zibert, John R; Skov, Lone; Thyssen, Jacob P

2010-01-01

the expression and significance of S100A4 in psoriasis. We found significant upregulation of S100A4 in the dermis of psoriatic skin compared with normal skin. This pattern of S100A4 expression differs considerably from that of other S100 proteins, S100A7 and S100A8/9, with predominant expression in the epidermis...... of psoriasis. Furthermore, we revealed a massive release of the biologically active forms of S100A4 from psoriatic skin. Interestingly, we found stabilization (increase) of p53 in the basal layer of epidermis in close proximity to cells expressing S100A4. To examine the possible implication of S100A4...... in the pathogenesis of psoriasis, we analyzed the effect of S100A4 blocking antibodies in a human psoriasis xenograft SCID mouse model and observed a significant reduction of the epidermal thickness and impairment in cell proliferation and dermal vascularization. In conclusion, we showed strong upregulation...

Structural and optical properties of Cu2ZnSnS4 thin film absorbers from ZnS and Cu3SnS4 nanoparticle precursors

International Nuclear Information System (INIS)

Lin, Xianzhong; Kavalakkatt, Jaison; Kornhuber, Kai; Levcenko, Sergiu; Lux-Steiner, Martha Ch.; Ennaoui, Ahmed

2013-01-01

Cu 2 ZnSnS 4 (CZTS) has been considered as an alternative absorber layer to Cu(In,Ga)Se 2 due to its earth abundant and environmentally friendly constituents, optimal direct band gap of 1.4–1.6 eV and high absorption coefficient in the visible range. In this work, we propose a solution-based chemical route for the preparation of CZTS thin film absorbers by spin coating of the precursor inks composed of Cu 3 SnS 4 and ZnS NPs and annealing in Ar/H 2 S atmosphere. X-ray diffraction and Raman spectroscopy were used to characterize the structural properties. The chemical composition was determined by energy dispersive X-ray spectroscopy. Optical properties of the CZTS thin film absorbers were studied by transmission, reflection and photoluminescence spectroscopy

Nanostructurization effects in PVP-stabilized tetra-arsenic tetra-sulfide As{sub 4}S{sub 4} nanocomposites

Energy Technology Data Exchange (ETDEWEB)

Shpotyuk, O., E-mail: olehshpotyuk@yahoo.com [Institute of Physics of Jan Dlugosz University in Czestochowa, 13/15, Al. Armii Krajowej, Czestochowa, 42200 (Poland); Vlokh Institute of Physical Optics, 23, Dragomanov Str., Lviv, 79005 (Ukraine); Scientific Research Company “Carat”, 202, Stryjska Str., 79031, Lviv (Ukraine); Bujňáková, Z.; Baláž, P. [Institute of Geotechnics of Slovak Academy of Sciences, 45, Watsonova Str., Košice, 04001 (Slovakia); Ingram, A. [Opole University of Technology, 75, Ozimska Str., Opole, 45370 (Poland); Demchenko, P. [Ivan Franko National University of Lviv, 1, Universytetska Str., 79000 Lviv (Ukraine); Kovalskiy, A. [Department of Physics & Astronomy, Austin Peay State University, Clarksville, TN, 37044 (United States); Vlcek, M. [Department of General and Inorganic Chemistry, Faculty of Chemistry, University of Pardubice, 532 10, Pardubice (Czech Republic); Shpotyuk, Ya. [Ivan Franko National University of Lviv, 1, Universytetska Str., 79000 Lviv (Ukraine); Centre for Innovation and Transfer of Natural Sciences and Engineering Knowledge, 1, Pigonia Str., 35310, Rzeszow (Poland); Cebulski, J.; Dziedzic, A. [Centre for Innovation and Transfer of Natural Sciences and Engineering Knowledge, 1, Pigonia Str., 35310, Rzeszow (Poland)

2017-01-15

Nanostructurization in three types of tetra-arsenic tetra-sulfide As{sub 4}S{sub 4} polymorphs composed by (1) preferential β-As{sub 4}S{sub 4}, (2) realgar α-As{sub 4}S{sub 4} and (3) admixture of As{sub 4}S{sub 4} in the form of β-realgar, pararealgar and intermediate χ-phase subjected to mechanochemical ball milling in a water solution of polyvinylpyrrolidone (PVP) are characterized with multiexperimental structure-sensitive probes. Void structure of pelletized As{sub 4}S{sub 4}-PVP nanocomposites is probed by positron annihilation lifetime spectroscopy complemented with atomic-sensitive techniques such as X-ray powder diffraction, Raman scattering and scanning electron microscopy with energy-dispersive X-ray spectroscopy. Appearance of arsenolite As{sub 2}O{sub 3} crystallites is character for all As{sub 4}S{sub 4} polymorphs affected by wet milling. Positron annihilation lifetime data considered in terms of substitution positron-positronium trapping confirm complicated nature of nanocomposites. Modified x3-x2-coupling decomposition algorithm developed in addition to unconstrained x3-term fitting procedure is applied to parameterize annihilation channels in these nanocomposites. Interfacial free-volume voids between neighboring nanoparticles in PVP environment are defined as most favorable trapping sites, they being rather loosely composed by As{sub 4}S{sub 4} crystallites in full respect to variety of crystallographic polymorphs used for milling. Detected annihilation channels are ascribed preferentially to intrinsic free-volume voids insensitive to trapping states at the surface of oxidized nanocomposites. - Highlights: • PVP-stabilized tetra-arsenic tetra-sulfide nanocomposites prepared by wet milling. • As{sub 4}S{sub 4}-PVP composites by complementary atomic-specific and deficient structure probes. • Surface oxidation due to crystalline arsenolite As{sub 2}O{sub 3} under wet milling. • Free-volume structure of PVP-stabilized As{sub 4}S{sub 4

NMR of proteins (4Fe-4S): structural properties and intramolecular electron transfer

International Nuclear Information System (INIS)

Huber, J.G.

1996-01-01

NMR started to be applied to Fe-S proteins in the seventies. Its use has recently been enlarged as the problems arising from the paramagnetic polymetallic clusters ware overcome. Applications to [4Fe-4S] are presented herein. The information derived thereof deepens the understanding of the redox properties of these proteins which play a central role in the metabolism of bacterial cells. The secondary structure elements and the overall folding of Chromatium vinosum ferredoxin (Cv Fd) in solution have been established by NMR. The unique features of this sequence have been shown to fold as an α helix at the C-terminus and as a loop between two cysteines ligand of one cluster: these two parts localize in close proximity from one another. The interaction between nuclear and electronic spins is a source of additional structural information for (4Fe-AS] proteins. The conformation of the cysteine-ligands, as revealed by the Fe-(S γ -C β -H β )Cys dihedral angles, is related to the chemical shifts of the signals associated with the protons of these residues. The longitudinal relaxation times of the protons depend on their distance to the cluster. A quantitative relationship has been established and used to show that the solution structure of the high-potential ferredoxin from Cv differs significantly from the crystal structure around Phe-48. Both parameters (chemical shifts and longitudinal relaxation times) give also insight into the electronic and magnetic properties of the [4Fe-4S] clusters. The rate of intramolecular electron transfer between the two [4FE-4S] clusters of ferredoxins has been measured by NMR. It is far slower in the case of Cv Fd than for shorter ferredoxins. The difference may be associated with changes in the magnetic and/or electronic properties of one cluster. The strong paramagnetism of the [4Fe-4S] clusters, which originally limited the applicability of NMR to proteins containing these cofactors, has been proven instrumental in affording new

Self-broadening and shifting of the Li(2s-2p) and K(4s-4p) line cores

International Nuclear Information System (INIS)

Reggami, L.; Bouledroua, M.; Allouche, A.R.; Aubert-Frecon, M.

2009-01-01

The aim of this work is to determine quantum mechanically the width Γ and the shift Δ of the lithium Li(2p→2s) and potassium K(4p→4s) resonance lines when these atoms are evolving in their parent gases. The interaction potentials along which the atoms Li(2p)+Li(2s) and K(4p)+K(4s) approach each other are constructed from reliable data. The radial wave equation is then solved numerically by using these potentials to compute the elastic phase shifts. By adopting the simplified Baranger model for the pressure broadening, which assumes the impact approximation, the cross sections effective in linewidth and lineshift are analyzed. The analysis leads in particular to the determination of the width and shift rates and the computations show that these rates have constant values and, mainly, do not depend on temperature. An approximate method is further applied to the calculations of the cross sections. The results reveal the influence of the long-range -C 3 /R 3 interactions and confirm the universality of the obtained formulas of Γ and Δ

Samsung Galaxy S4 for dummies

CERN Document Server

Hughes, Bill

2013-01-01

Explore a world of possibilities with your Samsung Galaxy S 4 smartphone Everything's more exciting when you've got the Galaxy in your hand. Let For Dummies be your guide to getting the most out of your Galaxy S 4. You'll cruise through the smartphone basics and set up process before moving on to the fun stuff like staying in touch with e-mail and texting, surfing the web, navigating with maps, shooting and sharing photos and video, watching movies, listening to music, and so much more. Whether you're entering the smartphone world for the first time or just moving up to

Internationalization of Bachelor’s programmes in Social Work in Europe

Directory of Open Access Journals (Sweden)

Peter Hendriks

2016-03-01

Full Text Available Internationalization of Bachelor’s programmes in Social Work in EuropeThis article presents the results of a survey on the internationalization of Bachelor’s education in social work, which was carried out at 33 schools of social work across Europe. Many universities are seeking to “internationalize” their social work curriculum. However, although many social work educators are convinced of the importance of cross-border exchange, others are sceptical about the added value of internationalization for a professional career in social work. The aim of this study is to contribute to the discussion about the significance of internationalizing the curriculum of Bachelor’s programmes in social work. Since internationalization in itself is an ideological endeavour, educators must reflect on and formulate their own ideological motives and aspirations. To this end, representatives of schools of social work completed a questionnaire concerning the aim of internationalization, the structure of the curriculum, student and staff mobility, international policies and challenges. This study demonstrates that all universities have added an international dimension to their curricula. Many educators believe that internationalizing the social work curriculum contributes to qualitatively better future professionals “at home”. However, most of the respondents are dissatisfied with what has actually been achieved in terms of their universities’ international ambitions. This is due to a lack of language skills and facilities. Above all, we think, that this dissatisfaction is related to the underlying debate on universalism and indigenization in social work practice and education.  SAMENVATTINGDe internationalisering van de bachelors sociaal werk in EuropaIn dit artikel worden de uitkomsten gepresenteerd van een survey naar internationalisering van het sociaal werk bachelor onderwijs, uitgevoerd onder 33 opleidingen sociaal werk, verspreid over Europa

Living, Breathing Songs: Singing Along with Bob Dylan

Directory of Open Access Journals (Sweden)

Keith Negus

2007-03-01

Full Text Available Taking issue with approaches to Bob Dylan’s art that are preoccupied with his lyrics, this article suggests a route into thinking about his music by focusing on how Dylan’s vocal melodies work at the intersection of speech and singing. Drawing on Gino Stefani’s work on popular melodies, this article explores this issue through a discussion of how people sing along with Dylan’s songs at concerts. The discussion focuses on the song “It Ain’t Me Babe,” and examines more general points about the ways in which Dylan’s melodies connect with the everyday lives of his listeners.

Joint German/French S4-Analytical Report

International Nuclear Information System (INIS)

Miemczyk, H.

1979-03-01

A joint German/French program was initiated to investigate in detail the behaviour of artificially defected fuel pins in a sodium loop of the SILOE reactor at Grenoble/France. Three irradiation experiments have been conducted in SILOE on representative SNR-type fuel pins (mixed oxide, low density, stainless steel cladding, external diameter 6 mm). The first experiment, S2, had been an unirradiated pin with a large interstitial defect (machined slit of 30x1 mm). The two following pins, S4 and S3, have been pre-irradiated in RAPSODIE (365 efpd, 10.6 % burnup). The main results of the S4-experiment are described and evaluated in the present report. They concern the following important aspects: sodium-uranate/plutonate formation and its kinetics, fuel loss, fission product release and fuel behaviour

Photoelectric properties and charge dynamics in ZnO nanowires/Cu{sub 4}Bi{sub 4}S{sub 9} and ZnO nanowires/In{sub 2}O{sub 3}/Cu{sub 4}Bi{sub 4}S{sub 9} heterostructures

Energy Technology Data Exchange (ETDEWEB)

Liu, Xiangyang, E-mail: lxy081276@126.com, E-mail: yzgu@henu.edu.cn; Wang, Shun; Gu, Yuzong, E-mail: lxy081276@126.com, E-mail: yzgu@henu.edu.cn [Institue of Microsystems Physics and School of Physics and Electronics, Henan University, Kaifeng 475004 (China); Zhang, Jingwei; Zhang, Jiwei [The Key Laboratory for Special Functional Materials of MOE, Henan University, Kaifeng 475004 (China)

2014-12-28

ZnO nanowires arrays were preformed in a horizontal double-tube system. Two types of heterostructures (ZnO nanowires/Cu{sub 4}Bi{sub 4}S{sub 9} and ZnO nanowires/In{sub 2}O{sub 3}/Cu{sub 4}Bi{sub 4}S{sub 9}) and three-dimensional solar cells were fabricated with ZnO nanowires arrays as working electrode, In{sub 2}O{sub 3} as buffer layer, and Cu{sub 4}Bi{sub 4}S{sub 9} as inorganic dye and hole collector. It is suggested that two types of heterostructures have the similar absorption properties with single Cu{sub 4}Bi{sub 4}S{sub 9}. However, the results of steady state and electric field-induced surface photovoltage indicate that ZnO nanowires/In{sub 2}O{sub 3}/Cu{sub 4}Bi{sub 4}S{sub 9} exhibits the higher photovoltaic response than ZnO nanowires/Cu{sub 4}Bi{sub 4}S{sub 9}. Using the transient surface photovoltage spectroscopy, we further studied the separation and transport mechanism of photogenerated charges. Furthermore, Cu{sub 4}Bi{sub 4}S{sub 9}/In{sub 2}O{sub 3}/ZnO cells presents the better performance than Cu{sub 4}Bi{sub 4}S{sub 9}/ZnO cells and the highest efficiencies are about 6.4% and 5.2%, respectively. It is suggested that direct paths, interface barrier, built-in electric field, and double energy level matchings between conduction bands (Cu{sub 4}Bi{sub 4}S{sub 9} and In{sub 2}O{sub 3}, In{sub 2}O{sub 3} and ZnO) have obvious effect on the separation of photogenerated charges. Then we discussed the synthetic action on the charge dynamics from these factors.

Experiment data report for semiscale Mod-1 Tests S-01-4 and S-01-4A (isothermal blowdown with core resistance simulator)

International Nuclear Information System (INIS)

Zender, S.N.; Jensen, M.F.; Sackett, K.E.

1975-03-01

Recorded test data are presented for Tests S-01-4 and S-01-4A of the semiscale Mod-1 isothermal blowdown test series. These tests are among several semiscale Mod-1 experiments which are counterparts of the planned Loss-of-Fluid Test (LOFT) nonnuclear experiments. System hardware is representative of LOFT design based on volumetric scaling methods, and initial conditions duplicate those identified for the LOFT nonnuclear tests. Tests S-01-4 and S-01-4A employed an intact loop resistance that was similar to that of Test S-01-3 and low relative to that of Test S-01-2. An orificed structure was used in the pressure vessel to simulate the LOFT core simulator. The tests were initiated at initial isothermal conditions of about 2250 psig and 540 0 F by a simulated offset shear of the cold-leg broken-loop piping. During system depressurization, coolant was injected into the cold leg of the intact loop to provide data on the effects of emergency core cooling on system response. Following the blowdown portion of Test S-01-4, coolant spray was introduced into the pressure suppression tank to determine the response of the pressure suppression system. The uninterpreted data are presented. The data, presented in the form of graphs in engineering units, have been analyzed only to the extent necessary to assure that they are reasonable and consistent. (U.S.)

Developmental Toxicity of (4S-2- (4-hydroxy-3-methoxyphenyl thiazolidine-4-carboxylic acid in Zebrafish ( Danio rerio

Directory of Open Access Journals (Sweden)

Cansu Akbulut

2017-08-01

Full Text Available ABSTRACT (4S-2-(4-hydroxy-3-methoxyphenylthiazolidine-4-carboxylic acid is new synthesized substance obtained from cysteine and valine. Thiazolidine derivates have important biological responses so scientists work intensively on these compounds in recent years. It is obvious that thiazolidine contained compounds will be used in future in the pharmaceutical industry to treat important diseases. Median lethal concentrations (LC50 for 48 h and 96 h were found as 1.106±0.052 mM and 0.804mM ± 0.102 respectively. According to LC50, exposure doses were determined as control, 0.4 mM, 0.2 mM and 0.1 mM (4S-2-(4-hydroxy-3-methoxyphenylthiazolidine-4-carboxylic acid. Developmental toxicity and apoptotic features on zebrafish development were evaluated in this study. The results of this study indicate that (4S-2-(4-hydroxy-3-methoxyphenylthiazolidine-4-carboxylic acid exposure cause developmental defects like pericardial edema, bent spine, tail malformation, blood accumulation, yolk sac edema but on the other hand concentration-dependent decrease in apoptotic rate. Likewise, concentration-dependent decrease in hatching and increase in mortality of embryos were also detected.

New supersymmetric AdS4 type II vacua

International Nuclear Information System (INIS)

Tsimpis, D.

2010-01-01

We review the supersymmetric AdS 4 x w M 6 backgrounds of type IIA/IIB supergravity constructed in[1]. In type IIA the supersymmetry is N=2, and the six-dimensional internal space is locally an S 2 bundle over a four-dimensional Kaehler-Einstein base; in IIB the internal space is the direct product of a circle and a five-dimensional squashed Sasaki-Einstein manifold. These backgrounds do not contain any sources, all fluxes (including the Romans mass in IIA) are generally non-zero, and the dilaton and warp factor are non-constant. The IIA solutions include the massive deformations of the IIA reduction of the eleven-dimensional AdS 4 x Y p,q solutions, and had been predicted to exist on the basis of the AdS 4 /CFT 3 correspondence. (Abstract Copyright [2010], Wiley Periodicals, Inc.)

Exploring a new S U (4 ) symmetry of meson interpolators

Science.gov (United States)

Glozman, L. Ya.; Pak, M.

2015-07-01

In recent lattice calculations it has been discovered that mesons upon truncation of the quasizero modes of the Dirac operator obey a symmetry larger than the S U (2 )L×S U (2 )R×U (1 )A symmetry of the QCD Lagrangian. This symmetry has been suggested to be S U (4 )⊃S U (2 )L×S U (2 )R×U (1 )A that mixes not only the u- and d-quarks of a given chirality, but also the left- and right-handed components. Here it is demonstrated that bilinear q ¯q interpolating fields of a given spin J ≥1 transform into each other according to irreducible representations of S U (4 ) or, in general, S U (2 NF). This fact together with the coincidence of the correlation functions establishes S U (4 ) as a symmetry of the J ≥1 mesons upon quasizero mode reduction. It is shown that this symmetry is a symmetry of the confining instantaneous charge-charge interaction in QCD. Different subgroups of S U (4 ) as well as the S U (4 ) algebra are explored.

Thermodynamic properties of CdCr2S4

International Nuclear Information System (INIS)

Kesler, Ya.A.; Shchelkotunov, V.A.; Tret'yakov, Yu.D.; Kamyshova, V.K.; Gordeev, I.V.; Alferov, V.A.

1977-01-01

The true thermal capacity of ferromagnetic chromium spinel CdCr 2 S 4 has been measured in the temperature range of 172-673 K. Coefficient of linear expansion has been measured in the temperature range of 173-677 K. A change in heat content of the compound has been found by the mixing method (298-750 K). The lattice contribution into thermal capacity, the contribution of thermal expansion, the values of isothermal compressibility factor, and the Crueneisen constants have been calculated from true and mean heat capacity of CdCr 2 S 4 in a wide temperature range. The lattice energy V has been calculated for CdCr 2 S 4 ; it amounts -4226 kcal/mol

HISTOPATHOLOGICAL EFFECTS OF (4S)-2-(4-HYDROXY-3-METHOXYPHENYL) THIAZOLIDINE-4-CARBOXYLIC ACID ON ZEBRAFISH (Danio rerio) HEART TISSUE

OpenAIRE

YÖN, Nazan Deniz; ÖZTÜRK, Burcu; ZENGİN, Mustafa; AKBULUT, Cansu

2018-01-01

Examination thehistopathological effects of (4s)-2-(4-hydroxy-3-methoxyphenyl) thiazolidine-4-carboxylicacid on heart tissue of zebrafish were aimed.Introduction:(4S)-2-(4-hydroxy-3-methoxyphenyl) thiazolidine-4-carboxylic acid is newsynthesized substance which obtained from cysteine and valine. Because ofthiazolidine derivates have important biological responses scientist workintensively on these compounds recent years. It is obvious that thiazolidinecontained compounds will be used in futur...

Crystal structure of the Hg4SiS6 and Hg4SiSe6 compounds

International Nuclear Information System (INIS)

Gulay, L.D.; Olekseyuk, I.D.; Parasyuk, O.V.

2002-01-01

The crystal structures of Hg 4 SiS 6 and Hg 4 SiSe 6 compounds were investigated using X-ray powder diffraction. These compounds crystallize in the monoclinic Cc space group with the lattice parameters a=1.23020(5), b=0.71031(4), c=1.22791(4) nm, β=109.721(3) deg. for Hg 4 SiS 6 and a=1.28110(4), b=0.74034(4), c=1.27471(1) nm, β=109.605(3) deg. for Hg 4 SiSe 6 . Atomic parameters were refined in the isotropic approximation (R I =0.0571 and R I =0.0555 for the Hg 4 SiS 6 and Hg 4 SiSe 6 , respectively)

Electron Excitation Cross Sections for the S II Transitions: 3s(exp 2)3p(exp 3) 4S(exp o) approaches 3s(exp 2)3p(exp 3) 2D(exp o), 2P(exp o), and 3s3p(exp 4) 4P

Science.gov (United States)

Liao, C.; Chutjian, A.; Hitz, D.; Tayal, S. S.

1997-01-01

Experimental and theoretical collisional excitation cross sections are reported for the transitions 3s(exp 2)3p(exp 3)4S(exp o) approaches 3s(exp 2)3p(exp 3) 2D(exp o), 2P(exp o), and 3s3P(exp 4) 4P in S II. The transition wavelengths (energies) are 6716 A (1.85 eV), 4069 A (3.05 eV), and 1256 A (9.87 eV), respectively. In the experiments, use is made of the energy-loss merged-beams method. The metastable fraction of the S II beam was assessed and minimized. The contribution of elastically scattered electrons was reduced by the use of a lowered solenoidal magnetic field and a modulated radio-frequency voltage on the analyzing plates and by retarding grids to reject the elastically scattered electrons with larger Larmor radii. For each transition, comparisons are made among experiments, the new 19 state R-matrix calculation, and three other close-coupling calculations.

Exploring the ϒ (4 S ,5 S ,6 S )→hb(1 P )η hidden-bottom hadronic transitions

Science.gov (United States)

Zhang, Yawei; Li, Gang

2018-01-01

Recently, the Belle Collaboration has reported the measurement of the spin-flipping transition ϒ (4 S )→hb(1 P )η with an unexpectedly large branching ratio: B (ϒ (4 S )→hb(1 P )η )=(2.18 ±0.11 ±0.18 )×10-3 . Such a large branching fraction contradicts with the anticipated suppression for the spin flip. In this work, we examine the effects induced by intermediate bottomed meson loops and point out that these effects are significantly important. Using the effective Lagrangian approach (ELA), we find the experimental data on ϒ (4 S )→hb(1 P )η can be accommodated with the reasonable inputs. We then explore the decays ϒ (5 S ,6 S )→hb(1 P )η and find that these two channels also have sizable branching fractions. We also calculate these processes in the framework of nonrelativistic effective field theory (NREFT). For the decays ϒ (4 S )→hb(1 P )η , the NREFT results are at the same order of magnitude but smaller than the ELA results by a factor of 2 to 5. For the decays ϒ (5 S ,6 S )→hb(1 P )η , the NREFT results are smaller than the ELA results by approximately 1 order of magnitude. We suggest a future experiment Belle-II to search for the ϒ (5 S ,6 S )→hb(1 P )η decays, which will be helpful for understanding the transition mechanism.

Submersion-Subcritical Safe Space (S4) reactor

International Nuclear Information System (INIS)

King, Jeffrey C.; El-Genk, Mohamed S.

2006-01-01

The Submersion-Subcritical Safe Space (S 4 ) reactor, developed for future space power applications and avoidance of single point failures, is presented. The S 4 reactor has a Mo-14% Re solid core, loaded with uranium nitride fuel, cooled by He-30% Xe and sized to provide 550 kWth for 7 years of equivalent full power operation. The beryllium oxide reflector of the S 4 reactor is designed to completely disassemble upon impact on water or soil. The potential of using Spectral Shift Absorber (SSA) materials in different forms to ensure that the reactor remains subcritical in the worst-case submersion accident is investigated. Nine potential SSAs are considered in terms of their effect on the thickness of the radial reflector and on the combined mass of the reactor and the radiation shadow shield. The SSA materials are incorporated as a thin (0.1 mm) coating on the outside surface of the reactor core and as core additions in three possible forms: 2.0 mm diameter pins in the interstices of the core block, 0.25 mm thick sleeves around the fuel stacks and/or additions to the uranium nitride fuel. Results show that with a boron carbide coating and 0.25 mm iridium sleeves around the fuel stacks the S 4 reactor has a reflector outer diameter of 43.5 cm with a combined reactor and shadow shield mass of 935.1 kg. The S 4 reactor with 12.5 at.% gadolinium-155 added to the fuel, 2.0 mm diameter gadolinium-155 sesquioxide interstitial pins, and a 0.1 mm thick gadolinium-155 sesquioxide coating has a slightly smaller reflector outer diameter of 43.0 cm, resulting in a smaller total reactor and shield mass of 901.7 kg. With 8.0 at.% europium-151 added to the fuel, along with europium-151 sesquioxide for the pins and coating, the reflector's outer diameter and the total reactor and shield mass are further reduced to 41.5 cm and 869.2 kg, respectively

Pressure-induced phase transitions in single-crystalline Cu4Bi4S9 nanoribbons

International Nuclear Information System (INIS)

Hu Jing-Yu; Li Jing; Zhao Qing; Shi Li-Jie; Zou Bing-Suo; Zhang Si-Jia; Zhao Hao-Fei; Zhang Qing-Hua; Yao Yuan; Zhu Ke; Liu Yu-Long; Jin Chang-Qing; Yu Ri-Cheng; Li Yan-Chun; Li Xiao-Dong; Liu Jing

2013-01-01

In situ angle dispersive synchrotron X-ray diffraction and Raman scattering measurements under pressure are employed to study the structural evolution of Cu 4 Bi 4 S 9 nanoribbons, which are fabricated by using a facile solvothermal method. Both experiments show that a structural phase transition occurs near 14.5 GPa, and there is a pressure-induced reversible amorphization at about 25.6 GPa. The electrical transport property of a single Cu 4 Bi 4 S 9 nanoribbon under different pressures is also investigated

Is NiCo2S4 really a semiconductor?

KAUST Repository

Xia, Chuan

2015-08-31

NiCo2S4 is a technologically important electrode material that has recently achieved remarkable performance in pseu-docapacitor, catalysis, and dye-synthesized solar cell applications.[1-5] Essentially, all reports on this material have pre-sumed it to be semiconducting, like many of the chalcogenides, with a reported band-gap in the range of 1.2-1.7 eV.[6,7] In this report, we have conducted detailed experimental and theoretical studies, most of which done for the first time, which overwhelmingly show that NiCo2S4 is in fact a metal. We have also calculated the Raman spectrum of this mate-rial and experimentally verified it for the first time, hence clarifying inconsistent Raman spectra reports. Some of the key results that support our conclusions include: (1) the measured carrier density in NiCo2S4 is 3.18×1022 cm-3, (2) Ni-Co2S4 has a room temperature resistivity of around 103 µΩ cm which increases with temperature, (3) NiCo2S4 exhibits a quadratic dependence of the magnetoresistance on magnetic field, (4) thermopower measurements show an extremely low Seebeck coefficient of 5 µV K-1, (5) first principles calculations confirm that NiCo2S4 is a metal. These results sug-gest that it is time to re-think the presumed semiconducting nature of this promising material. They also suggest that the metallic conductivity is another reason (besides the known significant redox activity) behind the excellent perfor-mance reported for this material.

High critical magnetic field superconductor La3S4

International Nuclear Information System (INIS)

Westerholt, K.; Bach, H.; Wendemuth, R.; Methfessel, S.

1979-01-01

A report is presented on electrical conductivity, specific heat and magnetization measurements on La 3 S 4 single crystals. The results show that La 3 S 4 is a strong coupling superconductor with a BCS coherence length of 132 A. This extremely low value makes La 3 S 4 an intrinsic high critical magnetic field superconductor with a Landau-Ginsburg parameter of 20. For the temperature gradient of the upper critical magnetic field at the transition temperature values are found up to 35 kG/K. (author)

The relationship between personality traits and vocational interests

Directory of Open Access Journals (Sweden)

Gideon P. de Bruin

2002-09-01

Full Text Available This This study examined the relationship between vocational interests and basic personality traits. The interest fields of the 19-Field-Interest Inventory were related to the second order factors of the 16 Personality Factor Questionnaire by means of a factor extension analysis. The results showed that extroverts tend to be interested in fields related to social contact and the influencing of other people. Emotionally sensitive individuals tend to be interested in the arts and languages. Independent individuals tend to be interested in creative thinking. The implications of the findings for career counselling are discussed. Opsomming Hierdie studie het ondersoek ingestel na die verband tussen beroepsbelangstellings en basiese persoonlikheidstrekke. Die 19 belangstellingsvelde van die 19-Veld-belangstellings-vraelys is aan die hand van ’n faktorverlengingsontleding met die tweede orde faktore van die 16-Persoonlikheids-faktorvraelys in verband gebring. Die resultate dui daarop dat ekstroverte geneig is omin veldewat sosiale kontak en die beinvloeding vanmense behels, belang te stel. Emosioneel sensitiewe individue is geneig om in kunssinnge en taal verwante velde belang te stel. Onafhanklike individue is geneig om in kreatiewe denke belang te stel. Die implikasies van die resultate vir loopbaanvoorligting word bespreek.

Computational Chemistry of Modified [MFe3S4] and [M2Fe2S4] Clusters: Assessment of Trends in Electronic Structure and Properties

DEFF Research Database (Denmark)

Kepp, Kasper Planeta; Ooi, Bee Lean; Christensen, Hans Erik Mølager

2008-01-01

The aim of this work is to understand the molecular evolution of iron−sulfur clusters in terms of electronic structure and function. Metal-substituted models of biological [Fe4S4] clusters in oxidation states [MxFe4−xS4]3+/2+/1+ have been studied by density functional theory (M = Cr, Mn, Fe, Co, ...

Copper interactions in TlCu7S4 and TlCu7Se4

International Nuclear Information System (INIS)

Noren, L.; Delaplane, R.G.; Berger, R.

1999-01-01

Complete text of publication follows. The copper chalcogenides ACu 7 S 4 (A=NH 4 + , Tl + , Rb + ) are quasi-one-dimensional metals at ambient and higher temperatures which is due to the high mobility of copper in these structures. TlCu 7 S 4 and TlCu 7 Se 4 are isostructural compounds, space group I4/m, which can be described on the basis of a TlX 8 cube with two different Cu sites, Cu(1) and Cu(2). Cu(2)-Cu(2) zigzag chains run along the c axis with only 3/4 occupation of the Cu(2) sites. However, these two compounds differ in behaviour on cooling. The sulphide shows a polymorphic first-order transition to the CsAg 7 S 4 type (P4/n) owing to ordering of the vacancies in the Cu(2)-Cu(2) chains. In order to study the nature of the Cu(2) order/disorder in the two title compounds, a series of neutron diffraction measurements (both Bragg and diffuse scattering) were made at several temperatures from 40 to 713 K on the instrument SLAD at Studsvik. The structure at each temperature was modelled using RMC techniques. The resulting configuration show that as the temperature increases, there is a marked increase in the mobility of the Cu atoms in the Cu(2)-Cu(2) chains for TlCu 7 S 4 but not for TlCu 7 Se 4 . This is due to the initial difference in the Cu(2)-Cu(2) distances, only 2.2A for the thiocuprate, but 2.7A in the selenocuprate which explains the relative ease for Cu(2) ordering in the latter case. (author)

Emissions in potassium vapour under 4S1/2-7S1/2 two-photon nsec excitation

International Nuclear Information System (INIS)

Pentaris, D.; Chatzikyriakos, G.; Armyras, A.; Efthimiopoulos, T.

2010-01-01

The two-photon excitation of 4S 1/2 -7S 1/2 transition of potassium atoms is studied. Several coherent emissions and processes are possible, such as parametric four-wave (PFWM), parametric six-wave (PSWM) mixing and competition with the stimulated hyper Raman (SHRS) and the amplified spontaneous emission (ASE). The radiations at the transitions 6P 3/2,1/2 -4S 1/2 , 6S 1/2 -4P 3/2,1/2 and 5P 3/2,1/2 -4S 1/2 are emitted only in the forward direction (indicating a parametric process), while the radiation at the transition 4P 3/2,1/2 -4S 1/2 is emitted in the forward and in the backward direction, indicating an ASE process.

Fast-electron-impact study on excitations of 4p, 4s, and 3d electrons of krypton

International Nuclear Information System (INIS)

Yuan Zhensheng; Zhu Linfan; Liu Xiaojing; Li Wenbin; Cheng Huadong; Xu Kezun; Zhong Zhiping

2002-01-01

Absolute optical oscillator strength densities for the excitations of the electrons 4p, 4s, and 3d have been measured. Their absolute optical oscillator strengths have also been obtained. An enhancement above the 4p ionization threshold in the photoabsorption spectrum was assigned as a delayed maximum which arises from the photoionization process of 4p→εd according to present Dirac-Slater calculation. In the energy region of 4s autoionization, we have observed several features that are absent in previous fast-electron-impact work, but exist in optical measurements. We clarify this discrepancy here. Two Rydberg series of optically forbidden transitions, i.e., 4s -1 ns( 1 S) (n=5,6,7) and 4s -1 nd( 1 D) (n=4,5,6,7) have been observed when the spectrometer worked at conditions with larger momentum transfers, namely, K 2 =0.23 a.u. and 0.67 a.u. Furthermore, the absolute optical oscillator strengths for the 3d excitation have been obtained

Isotope shift of 40,42,44,48Ca in the 4s 2S1/2 → 4p 2P3/2 transition

Science.gov (United States)

Gorges, C.; Blaum, K.; Frömmgen, N.; Geppert, Ch; Hammen, M.; Kaufmann, S.; Krämer, J.; Krieger, A.; Neugart, R.; Sánchez, R.; Nörtershäuser, W.

2015-12-01

We report on improved isotope shift measurements of the isotopes {}{40,42,{44,48}}Ca in the 4{{s}}{ }2{{{S}}}1/2\\to 4{{p}}{ }2{{{P}}}3/2 (D2) transition using collinear laser spectroscopy. Accurately known isotope shifts in the 4{{s}}{ }2{{{S}}}1/2\\to 4{{p}}{ }2{{{P}}}1/2(D1) transition were used to calibrate the ion beam energy with an uncertainty of {{Δ }}U≈ +/- 0.25 {{V}}. The accuracy in the D2 transition was improved by a factor of 5-10. A King-plot analysis of the two transitions revealed that the field shift factor in the D2 line is about 1.8(13)% larger than in the D1 transition which is ascribed to relativistic contributions of the 4{{{p}}}1/2 wave function.

CMB-S4 Science Book, First Edition

Energy Technology Data Exchange (ETDEWEB)

Abazajian, Kevork N. [Univ. of California, Irvine, CA (United States); et al.

2016-10-09

This book lays out the scientific goals to be addressed by the next-generation ground-based cosmic microwave background experiment, CMB-S4, envisioned to consist of dedicated telescopes at the South Pole, the high Chilean Atacama plateau and possibly a northern hemisphere site, all equipped with new superconducting cameras. CMB-S4 will dramatically advance cosmological studies by crossing critical thresholds in the search for the B-mode polarization signature of primordial gravitational waves, in the determination of the number and masses of the neutrinos, in the search for evidence of new light relics, in constraining the nature of dark energy, and in testing general relativity on large scales.

Anticonvulsant activity of a mGlu(4alpha) receptor selective agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid.

Science.gov (United States)

Chapman, A G; Talebi, A; Yip, P K; Meldrum, B S

2001-07-20

The metabotropic Group III agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid (ACPT-1), selective for the mGlu(4alpha) receptor, suppresses sound-induced seizures in DBA/2 mice following its intracerebroventricular (i.c.v.) administration (ED(50) 5.6 [2.9-10.7], nmol i.c.v., 15 min, clonic phase) and in genetically epilepsy-prone (GEP) rats following focal administration into the inferior colliculus (ED(50) 0.08 [0.01-0.50], nmol, 60 min, clonic phase). ACPT-1 also protects against clonic seizures induced in DBA/2 mice by the Group I agonist, (RS)-3,5-dihydroxyphenylglycine (3,5-DHPG) (ED(50) 0.60 [0.29-1.2], nmol i.c.v.) and by the Group III antagonist, (RS)-alpha-methylserine-O-phosphate (MSOP) (ED(50) 49.3 [37.9-64.1], nmol i.c.v.). Another Group III agonist, (RS)-4-phosphonophenyl-glycine (PPG), preferentially activating the mGlu(8) receptor, previously shown to protect against sound-induced seizures in DBA/2 mice and GEP rats, also protects against seizures induced in DBA/2 by 3,5-DHPG (ED(50) 3.7 [2.4-5.7], nmol i.c.v.) and by the Group III antagonist, MSOP (ED(50) 40.2 [21.0-77.0], nmol i.c.v.). At very high doses (500 nmol i.c.v. and above), Group III antagonists have pro-convulsant and convulsant activity. The anticonvulsant protection against sound-induced seizures in DBA/2 mice provided by a fully protective dose (20 nmol, i.c.v.) of the mGlu(4) receptor agonist ACPT-1, is partially reversed by the co-administration of the Group III antagonists, MSOP, (RS)-alpha-methyl-4-phosphonophenylglycine (MPPG) or (S)-2-amino-2-methyl-4-phosphonobutanoic acid (MAP4), in the 20-50 nmol dose range. At doses of 50-200 nmol, MPPG and MAP4 cause further reversal of the ACPT-1 anticonvulsant protection, while the MSOP effect on ACPT-1 protection is abolished at higher doses. In contrast, the anticonvulsant protection against sound-induced seizures in DBA/2 mice provided by a fully protective dose (20 nmol, i.c.v.) of the mGlu(8) receptor agonist PPG, is not

S100A9 interaction with TLR4 promotes tumor growth.

Directory of Open Access Journals (Sweden)

Eva Källberg

Full Text Available By breeding TRAMP mice with S100A9 knock-out (S100A9(-/- animals and scoring the appearance of palpable tumors we observed a delayed tumor growth in animals devoid of S100A9 expression. CD11b(+ S100A9 expressing cells were not observed in normal prostate tissue from control C57BL/6 mice but were readily detected in TRAMP prostate tumors. Also, S100A9 expression was observed in association with CD68(+ macrophages in biopsies from human prostate tumors. Delayed growth of TRAMP tumors was also observed in mice lacking the S100A9 ligand TLR4. In the EL-4 lymphoma model tumor growth inhibition was observed in S100A9(-/- and TLR4(-/-, but not in RAGE(-/- animals lacking an alternative S100A9 receptor. When expression of immune-regulating genes was analyzed using RT-PCR the only common change observed in mice lacking S100A9 and TLR4 was a down-regulation of TGFβ expression in splenic CD11b(+ cells. Lastly, treatment of mice with a small molecule (ABR-215050 that inhibits S100A9 binding to TLR4 inhibited EL4 tumor growth. Thus, S100A9 and TLR4 appear to be involved in promoting tumor growth in two different tumor models and pharmacological inhibition of S100A9-TLR4 interactions is a novel and promising target for anti-tumor therapies.

S100A9 Interaction with TLR4 Promotes Tumor Growth

Science.gov (United States)

Källberg, Eva; Vogl, Thomas; Liberg, David; Olsson, Anders; Björk, Per; Wikström, Pernilla; Bergh, Anders; Roth, Johannes; Ivars, Fredrik; Leanderson, Tomas

2012-01-01

By breeding TRAMP mice with S100A9 knock-out (S100A9−/−) animals and scoring the appearance of palpable tumors we observed a delayed tumor growth in animals devoid of S100A9 expression. CD11b+ S100A9 expressing cells were not observed in normal prostate tissue from control C57BL/6 mice but were readily detected in TRAMP prostate tumors. Also, S100A9 expression was observed in association with CD68+ macrophages in biopsies from human prostate tumors. Delayed growth of TRAMP tumors was also observed in mice lacking the S100A9 ligand TLR4. In the EL-4 lymphoma model tumor growth inhibition was observed in S100A9−/− and TLR4−/−, but not in RAGE−/− animals lacking an alternative S100A9 receptor. When expression of immune-regulating genes was analyzed using RT-PCR the only common change observed in mice lacking S100A9 and TLR4 was a down-regulation of TGFβ expression in splenic CD11b+ cells. Lastly, treatment of mice with a small molecule (ABR-215050) that inhibits S100A9 binding to TLR4 inhibited EL4 tumor growth. Thus, S100A9 and TLR4 appear to be involved in promoting tumor growth in two different tumor models and pharmacological inhibition of S100A9-TLR4 interactions is a novel and promising target for anti-tumor therapies. PMID:22470535

Treatment for GaSb surfaces using a sulphur blended (NH{sub 4}){sub 2}S/(NH{sub 4}){sub 2}SO{sub 4} solution

Energy Technology Data Exchange (ETDEWEB)

Murape, D.M., E-mail: Davison.Murape@nmmu.ac.za [Department of Physics, Nelson Mandela Metropolitan University, PO Box 77000, Port Elizabeth, 6031 (South Africa); Eassa, N.; Neethling, J.H. [Department of Physics, Nelson Mandela Metropolitan University, PO Box 77000, Port Elizabeth, 6031 (South Africa); Betz, R. [Department of Chemistry, Nelson Mandela Metropolitan University, PO Box 77000, Port Elizabeth, 6031 (South Africa); Coetsee, E.; Swart, H.C. [Department of Physics, University of the Free State, PO Box 339, Bloemfontein, 9300 (South Africa); Botha, J.R.; Venter, A. [Department of Physics, Nelson Mandela Metropolitan University, PO Box 77000, Port Elizabeth, 6031 (South Africa)

2012-07-01

A sulphur based chemical, [(NH{sub 4}){sub 2}S/(NH{sub 4}){sub 2}SO{sub 4}] to which S has been added, not previously reported for the treatment of (1 0 0) n-GaSb surfaces, is introduced and benchmarked against the commonly used passivants Na{sub 2}S{center_dot}9H{sub 2}O and (NH{sub 4}){sub 2}S. The surfaces of the treated material were studied by scanning electron microscopy (SEM), Auger electron spectroscopy (AES) and X-ray photoelectron spectroscopy (XPS). It has been found that the native oxides present on the GaSb surface are more effectively removed when treated with ([(NH{sub 4}){sub 2}S/(NH{sub 4}){sub 2}SO{sub 4}] + S) than with (NH{sub 4}){sub 2}S or Na{sub 2}S{center_dot}9H{sub 2}O, as evidenced by the ratio of the O{sub 506eV} to Sb{sub 457eV} AES peaks. XPS results reveal that Sb{sub 2}S{sub 3}/Sb{sub 2}S{sub 5} 'replaces' Sb{sub 2}O{sub 3}/Sb{sub 2}O{sub 5}, suggesting that sulphur atoms substitute oxygen atoms in Sb{sub 2}O{sub 3}/Sb{sub 2}O{sub 5} to form Sb-S. It seems sulphurization only partially removes Ga{sub 2}O{sub 3}. Treatment with ([(NH{sub 4}){sub 2}S/(NH{sub 4}){sub 2}SO{sub 4}] + S) also results in a noteworthy improvement in the current-voltage (I-V) characteristics of Au/n-GaSb Schottky contacts compared to those fabricated on as-received material.

Quaternary (FeIn{sub 2}S{sub 4}){sub x}(MnIn{sub 2}S{sub 4}){sub 1-x} alloys and photosensitive structures on their basis

Energy Technology Data Exchange (ETDEWEB)

Bodnar, I. V. [Belarusian State University of Informatics and Radioelectronics (Belarus); Rud, V. Yu., E-mail: rudvas.spb@gmail.com [St. Petersburg State Polytechnical University (Russian Federation); Rud, Yu. V. [Russian Academy of Sciences, Ioffe Physical Technical Institute (Russian Federation); Lozhkin, D. V. [Belarusian State University of Informatics and Radioelectronics (Belarus)

2011-07-15

Using directional crystallization of the melt of the (FeIn{sub 2}S{sub 4}){sub x}(MnIn{sub 2}S{sub 4}){sub 1-x} alloy, homogeneous crystals of a similar atomic composition are grown over the entire range of compositions 1 {>=} x {>=} 0. It is established that the crystals of the continuous series of quaternary alloys in the range x = 0-1 crystallize in the spinel structure and lattice parameter a linearly depends on x. It is established that it is possible to obtain In(Al)/(FeIn{sub 2}S{sub 4}){sub x}(MnIn{sub 2}S{sub 4}){sub 1-x} photosensitive structures. Room-temperature spectra of relative quantum efficiency of photoconversion of the In(Al)/(FeIn{sub 2}S{sub 4}){sub x}(MnIn{sub 2}S{sub 4}){sub 1-x} structures fabricated for the first time are obtained. From the analysis of these spectra, activation energies of direct and indirect band-to-band transitions for the crystals of the (FeIn{sub 2}S{sub 4}){sub x}(MnIn{sub 2}S{sub 4}){sub 1-x} alloys are determined and the dependence of these parameters on the composition of the position-disordered phases of mentioned alloys is discussed. It is concluded that the crystals of the (FeIn{sub 2}S{sub 4}){sub x}(MnIn{sub 2}S{sub 4}){sub 1-x} alloys can be used in broadband photoconverters of optical radiation.

High temperature neutron powder diffraction study of the Cu{sub 12}Sb{sub 4}S{sub 13} and Cu{sub 4}Sn{sub 7}S{sub 16} phases

Energy Technology Data Exchange (ETDEWEB)

Lemoine, Pierric, E-mail: pierric.lemoine@univ-rennes1.fr [Institut des Sciences Chimiques de Rennes, UMR-CNRS 6226, 263 Avenue du Général Leclerc, CS 74205, 35042 Rennes Cedex (France); Bourgès, Cédric; Barbier, Tristan [Laboratoire CRISMAT, UMR-CNRS 6508, ENSICAEN, 6 Boulevard du Maréchal Juin, 14050 Caen Cedex 04 (France); Nassif, Vivian [CNRS Institut NEEL, F-38000 Grenoble (France); Université de Grenoble Alpes, Institut NEEL, F-38000 Grenoble (France); Cordier, Stéphane [Institut des Sciences Chimiques de Rennes, UMR-CNRS 6226, 263 Avenue du Général Leclerc, CS 74205, 35042 Rennes Cedex (France); Guilmeau, Emmanuel [Laboratoire CRISMAT, UMR-CNRS 6508, ENSICAEN, 6 Boulevard du Maréchal Juin, 14050 Caen Cedex 04 (France)

2017-03-15

Ternary copper-containing sulfides Cu{sub 12}Sb{sub 4}S{sub 13} and Cu{sub 4}Sn{sub 7}S{sub 16} have attracted considerable interest since few years due to their high-efficiency conversion as absorbers for solar energy and promising thermoelectric materials. We report therein on the decomposition study of Cu{sub 12}Sb{sub 4}S{sub 13} and Cu{sub 4}Sn{sub 7}S{sub 16} phases using high temperature in situ neutron powder diffraction. Our results obtained at a heating rate of 2.5 K/min indicate that: (i) Cu{sub 12}Sb{sub 4}S{sub 13} decomposes above ≈792 K into Cu{sub 3}SbS{sub 3}, and (ii) Cu{sub 4}Sn{sub 7}S{sub 16} decomposes above ≈891 K into Sn{sub 2}S{sub 3} and a copper-rich sulfide phase of sphalerite ZnS-type structure with an assumed Cu{sub 3}SnS{sub 4} stoichiometry. Both phase decompositions are associated to a sulfur volatilization. While the results on Cu{sub 12}Sb{sub 4}S{sub 13} are in fair agreement with recent published data, the decomposition behavior of Cu{sub 4}Sn{sub 7}S{sub 16} differs from other studies in terms of decomposition temperature, thermal stability and products of reaction. Finally, the crystal structure refinements from neutron powder diffraction data are reported and discussed for the Cu{sub 4}Sn{sub 7}S{sub 16} and tetrahedrite Cu{sub 12}Sb{sub 4}S{sub 13} phases at 300 K, and for the high temperature form of skinnerite Cu{sub 3}SbS{sub 3} at 843 K. - Graphical abstract: In situ neutron powder diffraction data (heating rate of 2.5 K/min) indicates that (i) the ternary Cu{sub 12}Sb{sub 4}S{sub 13} phase is stable up to 792 K and decomposes at higher temperature into Cu{sub 3}SbS{sub 3} and Cu{sub 1.5}Sb{sub 0.5}S{sub 2}, and (ii) the Cu{sub 4}Sn{sub 7}S{sub 16} phase is stable up to 891 K and decomposes at higher temperature into Sn{sub 2}S{sub 3} and a cubic phase of sphalerite ZnS-type structure. Sulfur volatilization likely occurs in order to balance the overall stoichiometry.

Journal of Astrophysics and Astronomy | Indian Academy of Sciences

Indian Academy of Sciences (India)

, Hong Kong. Faculty of Physics, Babes-Bolyai University, Kogalniceanu Street 1, Cluj-Napoca 400 084, Romania. Department of Mathematics, Technical University of Cluj-Napoca, Memorandumului Street 28, Cluj Napoca 400 114, Romania.

The Rhyme of the Flying Bomb di Mervyn Peake: 125 quartine sul Blitz di Londra

OpenAIRE

Arianna Antonielli

2013-01-01

This essay addresses Mervyn Peake’s own memories of the Second World War Blitz and their migration into the poetical form of a ballad, The Rhyme of the Flying Bomb, composed in 1947. Abounding with Catholic symbolism, allegories and sea imagery, the poem tells the story of a sailor escaping from London bombing raids and his rescue of a new-born babe from a “golden drain”. The subsequent dialogue between the two protagonists reveals the fragile human side of the sailor and the divine prophetic...

Development of a Tetrathioether (S4) Bifunctional Chelate System for Rh-105

Science.gov (United States)

2013-07-01

olt s...500 0 500 1000 1500 mV olt s -500 0 500 1000 1500 (B) Free Rhodium Chloride Minutes 0 2 4 6 8 10 12 mV olt s 0 2000 4000 mV olt s 0 2000 4000 (C) Rh-S4...Diol prepared in water Minutes 0 2 4 6 8 10 12 mV olts 0 2000 4000 mV olts 0 2000 4000 (D) 105 Rh-S4Diol with cold [Rh-S4(OH)2-Diol] +

Synthesis and Characterization of Ferroelectric Liquid Crystalline Organosiloxanes Containing 4-(4-undecanyloxy bi-phenyl-1-carboxyloxyphenyl (2S,3S-2-chloro-3-methylvalerate and 4-(4-undecanyloxybenzoyloxybiphenyl (2S,3S-2-chloro-3-methylvalerate

Directory of Open Access Journals (Sweden)

Chih-Hung Lin

2013-10-01

Full Text Available A series of new organosiloxane ferroelectric liquid crystalline (FLC materials have been synthesized, and their mesomorphic and physical properties have been characterized. Four new disiloxanes and trisiloxanes, containing biphenyl 4-hydroxybenzoate and phenyl 4-hydroxybiphenylcarboxylate as mesogenic units and eleven methylene unit as spacers and (2S,3S-2-chloro-3-methylvalerate unit as chiral end groups. The molecule, using three phenyl ring as a mesogenic unit, formulates much wider liquid crystalline phase temperature ranges than that of a two phenyl ring unit. The phenyl arrangement differences of mesogenic unit result in the greater differences of the liquid crystal phase formation. The siloxane molecule induction is helpful to the more regular smectic phase formation and smectic phase stabilization, such as chiral SC (SC* and SB phases. The siloxane molecule is helpful to reduce the phase transition temperature and broaden the liquid crystal temperature range of the SC* phase and, simultaneously, it will not induce chain crystallization phenomenon and dilute the Ps value. The synthesis and characterization of the new FLCs materials, which exhibit a room temperature SC* phase and higher spontaneous polarization are presented.

Structural, elastic and thermodynamic properties under pressure and temperature effects of MgIn{sub 2}S{sub 4} and CdIn{sub 2}S{sub 4}

Energy Technology Data Exchange (ETDEWEB)

Bouhemadou, A., E-mail: a_bouhemadou@yahoo.fr [Laboratory for Developing New Materials and their Characterization, Department of Physics, Faculty of Science, University of Setif, 19000 Setif (Algeria); Haddadi, K. [Laboratory for Developing New Materials and their Characterization, Department of Physics, Faculty of Science, University of Setif, 19000 Setif (Algeria); Khenata, R. [Laboratoire de Physique Quantique et de Modelisation Mathematique (LPQ3M), Departement de Technologie, Universite de Mascara, 29000 Mascara (Algeria); Rached, D. [Department of Physics, Faculty of Science, University of Sidi-Bel-Abbes, 22000 (Algeria); Bin-Omran, S. [Department of Physics and Astronomy, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451 (Saudi Arabia)

2012-06-15

A density functional-based method is used to investigate the structural, elastic and thermodynamic properties of the cubic spinel semiconductors MgIn{sub 2}S{sub 4} and CdIn{sub 2}S{sub 4} at different pressures and temperatures. Computed ground structural parameters are in good agreement with the available experimental data. Single-crystal elastic parameters are calculated for pressure up to 10 GPa and temperature up to 1200 K. The obtained elastic constants values satisfy the requirement of mechanical stability, indicating that MgIn{sub 2}S{sub 4} and CdIn{sub 2}S{sub 4} compounds could be stable in the investigated pressure range. Isotropic elastic parameters for ideal polycrystalline MgIn{sub 2}S{sub 4} and CdIn{sub 2}S{sub 4} aggregates are computed in the framework of the Voigt-Reuss-Hill approximation. Pressure and thermal effects on some macroscopic properties such as lattice constant, volume expansion coefficient and heat capacities are predicted using the quasi-harmonic Debye model in which the lattice vibrations are taken into account.

DFT calculations on 1,4-dithiine and S-oxygenated derivatives

Directory of Open Access Journals (Sweden)

E. Vessally

2008-12-01

Full Text Available The molecular structures of 1,4-dithiine and S-oxygenated derivatives are studied using B3LYP/6-311++G** level of theory. These compounds have 8π-electrons in the ring. This led to stabilization of non-planar conformation. DFT calculations show that 1,4-dithiine, C4H4SS, 1,4-dithiine-1-oxide, C4H4SOS, 1,4-dithiine-1,4-dioxide, C4H4SOSO and 1,4-dithiine-1,1,4-trioxide, C4H4SO2SO; have boat conformation. 1,4-dithiine-1,1-dioxide, C4H4SO2S, have a shadow boat conformation. 1,4-dithiine-1,1,4,4-tetraoxide, C4H4SO2SO2, have a planar conformation.

Formation, spectroscopic characterization, and solution stability of an [Fe4S4]2+ cluster derived from β-cyclodextrin dithiolate.

Science.gov (United States)

Lo, Wayne; Zhang, Ping; Ling, Chang-Chun; Huang, Shaw; Holm, R H

2012-09-17

The formation and solution properties, including stability in mixed aqueous-Me(2)SO media, have been investigated for an [Fe(4)S(4)](2+) cluster derived from β-cyclodextrin (CD) dithiolate. Clusters of the type [Fe(4)S(4)(SAr)(4)](2-) (Ar = Ph, C(6)H(4)-3-F) are generated in Me(2)SO by redox reactions of [Fe(4)S(4)(SEt)(4)](2-) with 2 equiv of ArSSAr. An analogous reaction with the intramolecular disulfide of 6(A),6(D)-(3-NHCOC(6)H(4)-1-SH)(2)-6(A),6(D)-dideoxy-β-cyclodextrin (14), whose synthesis is described, affords a completely substituted cluster formulated as [Fe(4)S(4){β-CD-(1,3-NHCOC(6)H(4)S)(2)}(2)](2-) (15). Ligand binding is indicated by a circular dichroism spectrum and also by UV-visible and isotropically shifted (1)H NMR spectra and redox behavior convincingly similar to [Fe(4)S(4)(SPh)(4)](2-). One formulation of 15 is a single cluster to which two dithiolates are bound, each in bidentate coordination. With there being no proven precedent for this binding mode, we show that the cluster [Fe(4)S(4)(S(2)-m-xyl)(2)](2-) is a single cubane whose m-xylyldithiolate ligands are bound in a bidentate arrangement. This same structure type was proposed for a cluster formulated as [Fe(4)S(4){β-CD-(1,3-SC(6)H(4)S)(2)}(2)](2-) (16; Kuroda et al. J. Am. Chem. Soc.1988, 110, 4049-4050) and reported to be water-stable. Clusters 15 and 16 are derived from similar ligands differing only in the spacer group between the thiolate binding site and the CD platform. In our search for clusters stable in aqueous or organic-aqueous mixed solvents that are potential candidates for the reconstitution of scaffold proteins implicated in cluster biogenesis, 15 is the most stable cluster that we have thus far encountered under anaerobic conditions in the absence of added ligand.

Hydrogen Evolution on Supported Incomplete Cubane-type [Mo3S4](4+) Electrocatalysts

DEFF Research Database (Denmark)

Jaramillo, Thomas; Bonde, Jacob Lindner; Zhang, Jingdong

2008-01-01

Electrocatalytic properties of biomimetic supported incomplete cubane-type [Mo3S4](4+) clusters are investigated. The activity toward the hydrogen evolution reaction (HER) is evaluated on both a high surface area gas diffusion electrode in a membrane electrode assembly and on highly orientated...

Quantum electrodynamics effects in the 4s-4p transitions in Cu-like and Zn-like ions

International Nuclear Information System (INIS)

Cheng, K.; Wagner, R.A.

1987-01-01

Multiconfiguration Dirac-Fock energies are compared with experiment for the 4s-4p transitions in Cu-like ions and the 4s 2 1 S 0 --4s4p 1 P 1 transition in Zn-like ions for Au, Pb, Bi, Th, and U. The Coulomb, Breit, and QED contributions to these transitions are tabulated for selected ions in the range Z = 50--92. Results show that the agreement between theory and experiment is good enough to show the importance of QED corrections in the spectra of these highly stripped ions. Contrary to earlier findings by Seely et al. [Phys. Rev. Lett. 57, 2924 (1986)] we find no significant differences between the observed and calculated transition energies after finite-nuclear-size corrections are included

Holography for N=1{sup ∗} on S{sup 4}

Energy Technology Data Exchange (ETDEWEB)

Bobev, Nikolay [Instituut voor Theoretische Fysica, K.University Leuven,Celestijnenlaan 200D, B-3001 Leuven (Belgium); Elvang, Henriette; Kol, Uri; Olson, Timothy [Michigan Center for Theoretical Physics, Randall Laboratory of Physics,Department of Physics, University of Michigan,Ann Arbor, MI 48109 (United States); Pufu, Silviu S. [Joseph Henry Laboratories, Princeton University,Princeton, NJ 08544 (United States)

2016-10-18

We construct the five-dimensional supergravity dual of the N=1{sup ∗} mass deformation of the N=4 supersymmetric Yang-Mills theory on S{sup 4} and use it to calculate the universal contribution to the corresponding S{sup 4} free energy at large ’t Hooft coupling in the planar limit. The holographic RG flow solutions are smooth and preserve four supercharges. As a novel feature compared to the holographic duals of N=1{sup ∗} on ℝ{sup 4}, in our backgrounds the five-dimensional dilaton has a non-trivial profile, and the gaugino condensate is fixed in terms of the mass-deformation parameters. Important aspects of the analysis involve characterizing the ambiguities in the partition function of non-conformal N=1 supersymmetric theories on S{sup 4} as well as the action of S-duality on the N=1{sup ∗} theory.

Structural and optical properties of Cu{sub 2}ZnSnS{sub 4} thin film absorbers from ZnS and Cu{sub 3}SnS{sub 4} nanoparticle precursors

Energy Technology Data Exchange (ETDEWEB)

Lin, Xianzhong, E-mail: lin.xianzhong@helmholtz-berlin.de [Helmholtz-Zentrum Berlin für Materialien und Energie GmbH, Hahn-Meitner-Platz 1, D-14109 Berlin (Germany); Kavalakkatt, Jaison [Helmholtz-Zentrum Berlin für Materialien und Energie GmbH, Hahn-Meitner-Platz 1, D-14109 Berlin (Germany); Freie Universität Berlin, Berlin (Germany); Kornhuber, Kai; Levcenko, Sergiu [Helmholtz-Zentrum Berlin für Materialien und Energie GmbH, Hahn-Meitner-Platz 1, D-14109 Berlin (Germany); Lux-Steiner, Martha Ch. [Helmholtz-Zentrum Berlin für Materialien und Energie GmbH, Hahn-Meitner-Platz 1, D-14109 Berlin (Germany); Freie Universität Berlin, Berlin (Germany); Ennaoui, Ahmed, E-mail: ennaoui@helmholtz-berlin.de [Helmholtz-Zentrum Berlin für Materialien und Energie GmbH, Hahn-Meitner-Platz 1, D-14109 Berlin (Germany)

2013-05-01

Cu{sub 2}ZnSnS{sub 4} (CZTS) has been considered as an alternative absorber layer to Cu(In,Ga)Se{sub 2} due to its earth abundant and environmentally friendly constituents, optimal direct band gap of 1.4–1.6 eV and high absorption coefficient in the visible range. In this work, we propose a solution-based chemical route for the preparation of CZTS thin film absorbers by spin coating of the precursor inks composed of Cu{sub 3}SnS{sub 4} and ZnS NPs and annealing in Ar/H{sub 2}S atmosphere. X-ray diffraction and Raman spectroscopy were used to characterize the structural properties. The chemical composition was determined by energy dispersive X-ray spectroscopy. Optical properties of the CZTS thin film absorbers were studied by transmission, reflection and photoluminescence spectroscopy.

Expertise and humanity: the supportive professional relationship from the perspective of clients in drug treatment

Directory of Open Access Journals (Sweden)

Leila Billquist

2012-09-01

In onderzoek op het gebied van psychotherapie en sociaal werk wordt het belang van de relatie tussen professional en cliënt onderstreept. Het doel van dit artikel is om de kenmerken van ondersteunende professionele relaties vanuit het perspectief van cliënten binnen de verslavingszorg in kaart te brengen. Het onderzoek vond plaats in Zweden en omvatte kwalitatieve interviews en focusgroepsgesprekken met cliënten in vier residentiele instellingen. Uit de analyse van dit kwalitatieve materiaal kwamen vijf interactieve en elkaar deels overlappende thema’s, tezamen kenmerkend voor een ondersteunende professionele relatie, naar voren: (1 “De perfecte match” – de professional als persoon; (2 Fysieke en psychische aanwezigheid; (3 Net als vriendschap – maar toch niet helemaal; (4 Betrouwbare samenwerking; (5 Een voertuig voor flexibele en meervoudige ondersteuning.

Enhanced visible-light photocatalytic decomposition of 2,4-dichlorophenoxyacetic acid over ZnIn{sub 2}S{sub 4}/g-C{sub 3}N{sub 4} photocatalyst

Energy Technology Data Exchange (ETDEWEB)

Qiu, Pengxiang; Yao, Jinhua [Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse, Engineering Research Center for Chemical Pollution Control, Ministry of Education, School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094 (China); Chen, Huan, E-mail: hchen404@njust.edu.cn [Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse, Engineering Research Center for Chemical Pollution Control, Ministry of Education, School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094 (China); Jiang, Fang, E-mail: fjiang@njust.edu.cn [Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse, Engineering Research Center for Chemical Pollution Control, Ministry of Education, School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094 (China); Xie, Xianchuan [State Key Laboratory of Pollution Control and Resource Reuse, Center for Hydrosciences Research, School of the Environment, Nanjing University, Nanjing 210094 (China)

2016-11-05

Highlights: • A novel flower-on-sheet ZnIn{sub 2}S{sub 4}/g-C{sub 3}N{sub 4} nanocomposite was synthesized. • ZnIn{sub 2}S{sub 4}/g-C{sub 3}N{sub 4} showed high visible light catalytic activity for 2,4-D degradation. • The photocatalytic degradation pathway of 2,4-D was investigated. - Abstract: ZnIn{sub 2}S{sub 4}/g-C{sub 3}N{sub 4} heterojunction photocatalyst was successfully synthesized via a simple hydrothermal method and applied to visible-light photocatalytic decomposition of 2,4-dichlorophenoxyacetic acid (2,4-D) from aqueous phase. The flower-like ZnIn{sub 2}S{sub 4} particles were dispersed on the surface of g-C{sub 3}N{sub 4} nanosheets in the ZnIn{sub 2}S{sub 4}/g-C{sub 3}N{sub 4} composite. The composite showed higher separation rate of electron-hole pairs as compared to ZnIn{sub 2}S{sub 4} and g-C{sub 3}N{sub 4}. Consequently, the ZnIn{sub 2}S{sub 4}/g-C{sub 3}N{sub 4} composite exhibited enhanced visible light photocatalytic decomposition efficiency of 2,4-D, within 20% ZnIn{sub 2}S{sub 4}/g-C{sub 3}N{sub 4} composite owning the highest photocatalytic efficiency and initial rate. The initial rates of 2,4-D degradation on g-C{sub 3}N{sub 4}, ZnIn{sub 2}S{sub 4}, and 20% ZnIn{sub 2}S{sub 4}/g-C{sub 3}N{sub 4} were 1.23, 0.57 and 3.69 mmol/(g{sub cat} h), respectively. The h{sup +} and O{sub 2}{sup ·−} were found to be the dominant active species for 2,4-D decomposition. The photocatalytic degradation pathways of 2,4-D by ZnIn{sub 2}S{sub 4}/g-C{sub 3}N{sub 4} under visible light irradiation were explored. The ZnIn{sub 2}S{sub 4}/g-C{sub 3}N{sub 4} composite displayed high photostability in recycling tests, reflecting its promising potential as an effective visible light photocatalyst for 2,4-D treatment.

New Massive Gravity and AdS4 Counterterms

International Nuclear Information System (INIS)

Jatkar, Dileep P.; Sinha, Aninda

2011-01-01

We show that the recently proposed Dirac-Born-Infeld extension of new massive gravity emerges naturally as a counterterm in four-dimensional anti-de Sitter space (AdS 4 ). The resulting on-shell Euclidean action is independent of the cutoff at zero temperature. We also find that the same choice of counterterm gives the usual area law for the AdS 4 Schwarzschild black hole entropy in a cutoff-independent manner. The parameter values of the resulting counterterm action correspond to a c=0 theory in the context of the duality between AdS 3 gravity and two-dimensional conformal field theory. We rewrite this theory in terms of the gauge field that is used to recast 3D gravity as a Chern-Simons theory.

Crystal structures of the all-cysteinyl-coordinated D14C variant of Pyrococcus furiosus ferredoxin: [4Fe–4S] ↔ [3Fe–4S] cluster conversion

DEFF Research Database (Denmark)

Løvgreen, Monika Nøhr; Martic, Maja; Windahl, Michael S.

2011-01-01

The structure of the all-cysteinyl-coordinated D14C variant of [4Fe–4S] ferredoxin from the hyperthermophilic archaeon Pyrococcus furiosus has been determined to 1.7 Å resolution from a crystal belonging to space group C2221 with two types of molecules, A and B, in the asymmetric unit. A and B...... molecules have different crystal packing and intramolecular disulfide bond conformation. The crystal packing reveals a β-sheet interaction between A molecules in adjacent asymmetric units, whereas B molecules are packed as monomers in a less rigid position next to the A–A extended β-sheet dimers...... and purification are carried out at pH 5.8, only the monomer is obtained. The crystal structure of D14C [3Fe–4S] P. furiosus ferredoxin monomer was determined to 2.8 Å resolution from a crystal belonging to space group P212121 with two molecules in the asymmetric unit. The molecules resemble molecule A of D14C [4...

Ethical issues in recruitment of "healthy volunteers": study of a clinical research organisation in Hyderabad.

Science.gov (United States)

Krishna, Shilpa; Prasad, N Purendra

2014-01-01

This paper raises some of the ethical issues involved in the recruitment of healthy volunteers (HVs) by clinical research organizations (CROs) for bioavailability and bioequivalent (BA/BE) studies. It also explores the underlying reasons for the participation of the HVs and their interaction with the CROs. The findings are based on the data collected from 50 HVs participating in a BA/BE study conducted by a CRO in Hyderabad and from the key officials involved in it. The findings indicate the existence of various complex networks, throw some light on the role of middlemen ("Anna") and the negotiation process, and give us an insight into the social norms and values that compelled the HVs to participate in the study. The paper offers a critical analysis of a few ethical concerns.

STECH,4(2), S/NO 10, MAY, 2015

African Journals Online (AJOL)

Balogun

2015-05-10

May 10, 2015 ... 0.2(g).the characteristic cycle of ground motion is 0.35(s)~ 0.4(s).Because .... The additional stress in the cushion bottom is shown as figure 1: ... perspective of theoretical research and practical pay equal attention to, with the.

26 CFR 1.864-4 - U.S. source income effectively connected with U.S. business.

Science.gov (United States)

2010-04-01

....S. business. 1.864-4 Section 1.864-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... business of purchasing and selling vintage wines. During 1968, S establishes a branch office in the United... sales of, wine purchased by the home office. Negotiations for the sales of the electronic equipment take...

Energy Price Comparisons. Study on the quality of comparison sites for electricity and natural gas on the Internet; Energieprijsvergelijkers. Onderzoek naar de kwaliteit van vergelijkingssites voor elektriciteit en gas op het internet

Energy Technology Data Exchange (ETDEWEB)

Boezaard, P.M.; Van Liere, M.M.; Van Steenpaal, D.F.J.M.

2007-06-15

Internet sites with comparisons of prices for electricity and natural gas appear to be important tools for consumers. On a regular basis the Dutch Office of Energy Regulation (DTe) carries out a study on the quality of such price comparison sites. In this report the results of the June 2007 study are summarized. [Dutch] Voor een goedwerkende markt is een goed geinformeerde consument van belang. Uit de Consumentenmonitor, kwalitatief onderzoek dat de NMa in 2006 heeft laten uitvoeren, is gebleken dat de consument bij een overstap vaak gebruik maakt van prijsvergelijkingssites. Het belang van dergelijke sites neemt alleen maar toe. Door een grotere differentiatie aan producten en meer variatie in prijsstelling wordt een goede vergelijking van energieleveranciers voor de gemiddelde consument steeds lastiger. Ook voor de prijsvergelijkingssites neemt de complexiteit toe. De Directie Toezicht Energie (DTe) van de Nederlandse Mededingingsautoriteit (NMa) onderzoekt sinds 2004 jaarlijks de kwaliteit van (prijs)vergelijkingssites voor elektriciteit en gas. Gezien de groeiende complexiteit van de prijsvergelijkingen is het van belang dat de NMa dit onderzoek ook in 2007 uitvoert. In dit rapport worden de resultaten van dit jaar gepresenteerd. Daarnaast heeft de NMa voor het eerst een handleiding met tips voor de consument als bijlage bij dit rapport opgenomen.

Time of action of 4.5 S RNA in Escherichia coli translation

DEFF Research Database (Denmark)

Brown, S

1989-01-01

A new class of suppressor mutants helps to define the role of 4.5 S RNA in translation. The suppressors reduce the requirement for 4.5 S RNA by increasing the intracellular concentration of uncharged tRNA. Suppression probably occurs by prolonging the period in which translating ribosomes have...... translocated but not yet released the uncharged tRNA, indicating that this is the point at which 4.5 S RNA enters translation. The release of 4.5 S RNA from polysomes is affected by antibiotics that inhibit protein synthesis. The antibiotic-sensitivity of this release indicates that 4.5 S RNA exits...... the ribosome following translocation and prior to release of protein synthesis elongation factor G. These results indicate that 4.5 S RNA acts immediately after ribosomal translocation. A model is proposed in which 4.5 S RNA stabilizes the post-translocation state by replacing 23 S ribosomal RNA as a binding...

Phase diagram of ZnCr2pA12-2pS(Se)4 and Zn1-pCdpCr2S(Se)4

International Nuclear Information System (INIS)

Afif, K.; Benyoussef, A.; Hamedoun, M.; Hourmatallah, A.

1999-06-01

We compute the phase diagram of the nonmetallic compounds ZnCr2 p A1 2-2p S(Se) 4 (I[S,Se]) and Zn 1-p Cd p Cr 2 S(Se) 4 (II[S,Se]). We consider the bond-diluted Ising model on the spinel B site (S.B.S.) lattice with competitive exchange interactions, i.e. the ferromagnetic exchange interaction J 1 between nearest neighbours (n.n.) and the antiferromagnetic superexchange interaction J 2 between next-nearest neighbours' (n.n.n.) (and/or the more distant superexchange interactions J i (i > 1). Dilution and competition are found to be responsible for the spill glass phase and the percolation behaviour. (author)

Genes for 7S RNAs can replace the gene for 4.5S RNA in growth of Escherichia coli

DEFF Research Database (Denmark)

Brown, S

1991-01-01

4.5S RNAs of eubacteria and 7S RNAs of archaebacteria and eukaryotes exist in a hairpin conformation. The apex of this hairpin displays structural and sequence similarities among both 4.5S and 7S RNAs. Furthermore, a hyphenated sequence of 16 nucleotides is conserved in all eubacterial 4.5S RNAs...... examined. In this article I report that 7S RNAs that contain this 16-nucleotide sequence are able to replace 4.5S RNAs and permit growth of Escherichia coli....

Thin film electroluminescent cells on the basis of Ce-doped CaGa2S4 and SrGa2S4 prepared by flash evaporation method

International Nuclear Information System (INIS)

Gambarov, E.; Bayramov, A.; Kato, A.; Iida, S.

2006-01-01

Ce-doped CaGa 2 S 4 and SrGa 2 S 4 thin film electroluminescent (TFEL) devices were prepared for the first time on the basis of films deposited by flash evaporation method. Significant crystallization, stoichiometry improvement of the films and increase of photoluminescence intensity were found after annealing in H 2 S and O 2 gas stream. EL spectra of the cells exhibited the characteristic double-band emission similar to that seen for Ce 3+ activated CaGa 2 S 4 and SrGa 2 S 4 films under photon excitation. Applied voltage and frequency dependences of the electroluminescence were studied. Low voltage operation as low as 20 V was observed for these cells. Luminance of about 4 cd/m 2 at 100 V operating voltage with 2.5 kHz frequency was achieved for the TFEL cell with films annealed in O 2 gas stream. (copyright 2006 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

Antiviral and antifungal activity of some dermaseptin S4 analogues

African Journals Online (AJOL)

ajl yemi

2011-10-26

Oct 26, 2011 ... African Journal of Biotechnology Vol. ... dermaseptin S4 (DS-S4) that presents a potent cytotoxic effect. .... causing 100% cytotoxicity (CC) after 24 h of exposure .... Nicolas, 1994), it was shown that the mere deletion of 2.

Phase controlled solvothermal synthesis of Cu_2ZnSnS_4, Cu_2ZnSn(S,Se)_4 and Cu_2ZnSnSe_4 Nanocrystals: The effect of Se and S sources on phase purity

International Nuclear Information System (INIS)

Pal, Mou; Mathews, N.R.; Paraguay-Delgado, F.; Mathew, X.

2015-01-01

In this study, we have reported the synthesis of Cu_2ZnSnSe_4 (CZTSe), Cu_2ZnSnS_4 (CZTS) and Cu_2ZnSn(S,Se)_4 (CZTSSe) nanocrystals with tunable band gap and composition obtained by solvothermal method. The crystalline structure, composition, morphology and optical properties of the nanoparticles were characterized by X-ray diffraction (XRD), Raman scattering, energy dispersive X-ray spectroscopy, transmission electron microscopy and diffuse reflectance (DR) spectroscopy. While the XRD patterns of CZTS and CZTSe nanoparticles prepared with elemental S/Se powder revealed the presence of phase pure nanoparticles, the CZTSSe nanoparticles obtained using a mixture of S and Se, were found to contain many secondary phases under the same synthesis protocol. Formation of impurity phases in CZTSSe sample, can be avoided by using a mixture of 1-dodecanethiol (DT; CH_3(CH_2)_1_1SH)/oleylamine (OLA) instead of S powder and following the same experimental procedure. The incorporation of S in CZTSe nanocrystals prepared in presence of DDT/OLA mixture was confirmed through structural and optical characterizations. The optical properties of the quaternary chalcogenide nanocrystals were found to vary with the chemical composition of the material. - Highlights: • Solvothermal synthesis of CZTS, CZTSSe and CZTSe nanocrystals and discussion on possible formation mechanism. • Use of dodecanethiol/oleylamine mixture to synthesize phase-pure CZTSSe nanocrystals. • Formation of impurity phases can be controlled with proper S and Se sources.

Stage 4S neuroblastoma, a disseminated tumor with excellent outcome

International Nuclear Information System (INIS)

Elimam, Najla A.; Atra, Ayad A.; Fayea, Najwa Y.; Al-Asaad, Tareq G.; Khattab, Taha M.; Al-Sulami, Ganadeel A.; Felimban, Sami K.

2006-01-01

To review the clinical features and outcome of all cases of stage 4S neuroblastoma treated at our center. We retrospectively reviewed the files of all patients (n=75) with neuroblastoma treated at King Abdul-Aziz Medical City, Jeddah, Kingdom of Saudi Arabia between 1986 and 2005. We studied the clinical features and outcome of patients with stage 4S neuroblastoma. Six patients (8%) were confirmed to have stage 4S neuroblastoma. Three were boys with a median age at diagnosis of 4.5 months (range 28 days-11 moths). Four patients required no intervention. The remaining 2 patients were treated chemotherapy due to progressive hepatomegaly and respiratory distress. No patient required radiotherapy or surgical intervention. With a median follow up of four years (range 9 months --- 15.5 years), all patients are alive and well. Two patients continue to have a residual abdominal mass, while complete resolution occurred in the others. Stage 4S neuroblastoma is special tumor that carries excellent prognosis. Spontaneous regression may occur and intervention is only required in symptomatic patients. (author)

Magnetic charges in the AdS(4) superalgebra osp(4 vertical bar 2)

NARCIS (Netherlands)

Dibitetto, Giuseppe; Klemm, Dietmar

2010-01-01

We discuss the issue of how to include magnetic charges in the AdS(4) superalgebra osp(4 vertical bar 2). It is shown that the usual way of introducing a pseudoscalar central charge on the right hand side of the basic anticommutator does not work, because this breaks SO(2, 3) covariance. We propose

Quenching of 4He(21S,21P) and 3He(21S,21P) states by collisions with Ne(1S0) atoms

International Nuclear Information System (INIS)

Blagoev, K.B.; Dimova, E.; Petrov, G.M.

2004-01-01

The cross sections and rate constants for quenching 4 He(2 1 S), 4 He(2 1 P), 3 He(2 1 S) and 3 He(2 1 P) states by collisions with ground state Ne atoms are measured by a time-resolved method in a He-Ne electron beam excited plasma at low pressure. These rate constants at T g =600 K are: k 4 He(2 1 S) =(1.6±0.2)x10 -10 , k 4 He(2 1 P) =(3.4±2.5)x10 -10 , k 3 He(2 1 S) =(1.6±0.2)x10 -10 and k 3 He(2 1 P) =(5.7±1.2)x10 -10 cm 3 s -1 . The cross sections derived from the rate constant are σ 4 He(2 1 S) =(8.4±0.8)x10 -16 , σ 4 He(2 1 P) =(1.8±1.3)x10 -15 , σ 3 He(2 1 S) =(7.1±0.9)x10 -16 and σ 3 He(2 1 P) =(2.6±0.5)x10 -15 cm 2 , respectively. The diffusion coefficient of 3 He(2 1 S) in 3 He is estimated to be D 3 He(2 1 S)- 3 He =1.9D 4 He(2 1 S)- 4 He , based on comparison with 4 He. A time-dependent collisional radiative model for an e-beam sustained He-Ne plasma is developed and the predicted line intensity of NeI λ=6328 A line is compared with the experimental data. The influence of different processes involved in population and depopulation dynamics of He(2 1 S) state are evaluated

Characterization of the regions from E. coli 16 S RNA covalently linked to ribosomal proteins S4 and S20 after ultraviolet irradiation

International Nuclear Information System (INIS)

Ehresmann, B.; Backendorf, C.; Ehresmann, C.; Ebel, J.P.

1977-01-01

The use of ultraviolet irradiation to form photochemical covalent bonds between the 16 S RNA and a ribosomal protein is a reliable method to check RNA regions which are interacting with the protein. This technique was successfully used to covalently link RNA or DNA and specific proteins in several cases. In the case of ribosome, it has been shown that the irradiation of 30 S and 50 S subunits using high doses of ultraviolet light allowed the covalent binding of almost all of the ribosomal proteins to the 16 S or 23 S RNAs. Using mild conditions, only proteins S7 and L4 could be covalently linked to the 16 S and 23 S RNAs, respectively, and the 16 S RNA region linked to protein S7 has now been characterized. The specificity of the photoreaction was demonstrated earlier and the tryptic peptides from proteins S4 and S7, photochemically linked to the 16 S RNA complexes, were identified. A report is presented on the sequences of the RNA regions which can be photochemically linked to proteins S4 and S7 after ultraviolet irradiation of the specific S4-16 S RNA and 20 S-16 S RNA complexes

S100A4 amplifies TGF-β-induced fibroblast activation in systemic sclerosis

DEFF Research Database (Denmark)

Tomcik, Michal; Palumbo-Zerr, Katrin; Zerr, Pawel

2015-01-01

(SSc). METHODS: The expression of S100A4 was analysed in human samples, murine models of SSc and in cultured fibroblasts by real-time PCR, immunohistochemistry and western blot. The functional role of S100A4 was evaluated using siRNA, overexpression, recombinant protein and S100A4 knockout (S100A4...... or stimulation with recombinant S100A4 induced an activated phenotype in resting normal fibroblasts. In contrast, knockdown of S100A4 reduced the pro-fibrotic effects of TGF-β and decreased the release of collagen. S100A4(-/-) mice were protected from bleomycin-induced skin fibrosis with reduced dermal...

Higher spin gauge theory on fuzzy \\boldsymbol {S^4_N}

Science.gov (United States)

Sperling, Marcus; Steinacker, Harold C.

2018-02-01

We examine in detail the higher spin fields which arise on the basic fuzzy sphere S^4N in the semi-classical limit. The space of functions can be identified with functions on classical S 4 taking values in a higher spin algebra associated to \

SUSY S4×SU(5) revisited

International Nuclear Information System (INIS)

Hagedorn, Claudia; King, Stephen F.; Luhn, Christoph

2012-01-01

Following the recent results from Daya Bay and RENO, which measure the lepton mixing angle θ 13 l ≈0.15, we revisit a supersymmetric (SUSY) S 4 ×SU(5) model, which predicts tri-bimaximal (TB) mixing in the neutrino sector with θ 13 l being too small in its original version. We show that introducing one additional S 4 singlet flavon into the model gives rise to a sizable θ 13 l via an operator which leads to the breaking of one of the two Z 2 symmetries preserved in the neutrino sector at leading order (LO). The results of the original model for fermion masses, quark mixing and the solar mixing angle are maintained to good precision. The atmospheric and solar mixing angle deviations from TB mixing are subject to simple sum rule bounds.

High-Fidelity Computational Aerodynamics of the Elytron 4S UAV

Science.gov (United States)

Ventura Diaz, Patricia; Yoon, Seokkwan; Theodore, Colin R.

2018-01-01

High-fidelity Computational Fluid Dynamics (CFD) have been carried out for the Elytron 4S Unmanned Aerial Vehicle (UAV), also known as the converticopter "proto12". It is the scaled wind tunnel model of the Elytron 4S, an Urban Air Mobility (UAM) concept, a tilt-wing, box-wing rotorcraft capable of Vertical Take-Off and Landing (VTOL). The three-dimensional unsteady Navier-Stokes equations are solved on overset grids employing high-order accurate schemes, dual-time stepping, and a hybrid turbulence model using NASA's CFD code OVERFLOW. The Elytron 4S UAV has been simulated in airplane mode and in helicopter mode.

Ultrasonic investigation of GaV{sub 4}S{sub 8}

Energy Technology Data Exchange (ETDEWEB)

Cong, P.T.; Zherlitsyn, S.; Wosnitza, J. [Hochfeld-Magnetlabor Dresden, Helmholtz-Zentrum Dresden-Rossendorf, 01314 Dresden (Germany); Mombetsu, S. [Hochfeld-Magnetlabor Dresden, Helmholtz-Zentrum Dresden-Rossendorf, 01314 Dresden (Germany); Department of Physics, Hokkaido University (Japan); Tsurkan, V.; Loidl, A. [Institute of Physics, University of Augsburg, 86159 Augsburg (Germany)

2015-07-01

In recent years, transition metal-chalcogenides with the cubic GaMo{sub 4}S{sub 8}-type structure have attracted much interest because of their fascinating properties such as superconductivity under pressure, metal-insulator transition, 4d ferromagnetism and various structural and magnetic instabilities at low temperatures. These phenomena reflect the strong coupling of structural, electronic and magnetic degrees of freedom in this system. Here, we present results of ultrasound investigations performed on a high-quality single crystal of the tetrahedral magnetic-cluster material GaV{sub 4}S{sub 8}. The temperature dependence of the sound velocity and attenuation shows a huge anomaly at T{sub s} = 44 K followed by a pronounce feature at T{sub c} = 12.5 K related to a structural transition and ferromagnetic ordering, respectively, as known from previous magnetic-susceptibility and specific-heat results. A field-induced transition at temperatures below T{sub c} reveals a complex magnetic structure of GaV{sub 4}S{sub 8}, suggesting a competition of several interactions. Based on these measurements, we mapped out the B-T phase diagram of GaV{sub 4}S{sub 8} and discuss the role of the lattice degrees of freedom in this material.

Pop / Marko Mägi

Index Scriptorium Estoniae

Mägi, Marko

2004-01-01

Heliplaatidest: Erkki Hyva "Varjust rambini", Rush "Feedback", TV On The Radio "Desperate Youth, Blood Thirsty Babes", Ataxia "Automatic Writing", Michael Gordon "Light is Calling", Peccatum "Lost In Reverie", Felix da Housecat "Devin Dazzie and the Neon Fever"

4-Demethylwyosine Synthase from Pyrococcus abyssi Is a Radical-S-adenosyl-l-methionine Enzyme with an Additional [4Fe-4S]+2 Cluster That Interacts with the Pyruvate Co-substrate*

Science.gov (United States)

Perche-Letuvée, Phanélie; Kathirvelu, Velavan; Berggren, Gustav; Clemancey, Martin; Latour, Jean-Marc; Maurel, Vincent; Douki, Thierry; Armengaud, Jean; Mulliez, Etienne; Fontecave, Marc; Garcia-Serres, Ricardo; Gambarelli, Serge; Atta, Mohamed

2012-01-01

Wybutosine and its derivatives are found in position 37 of tRNA encoding Phe in eukaryotes and archaea. They are believed to play a key role in the decoding function of the ribosome. The second step in the biosynthesis of wybutosine is catalyzed by TYW1 protein, which is a member of the well established class of metalloenzymes called “Radical-SAM.” These enzymes use a [4Fe-4S] cluster, chelated by three cysteines in a CX3CX2C motif, and S-adenosyl-l-methionine (SAM) to generate a 5′-deoxyadenosyl radical that initiates various chemically challenging reactions. Sequence analysis of TYW1 proteins revealed, in the N-terminal half of the enzyme beside the Radical-SAM cysteine triad, an additional highly conserved cysteine motif. In this study we show by combining analytical and spectroscopic methods including UV-visible absorption, Mössbauer, EPR, and HYSCORE spectroscopies that these additional cysteines are involved in the coordination of a second [4Fe-4S] cluster displaying a free coordination site that interacts with pyruvate, the second substrate of the reaction. The presence of two distinct iron-sulfur clusters on TYW1 is reminiscent of MiaB, another tRNA-modifying metalloenzyme whose active form was shown to bind two iron-sulfur clusters. A possible role for the second [4Fe-4S] cluster in the enzyme activity is discussed. PMID:23043105

Smart Chips for Smart Surroundings -- 4S

NARCIS (Netherlands)

Schuler, Eberhard; König, Ralf; Becker, Jürgen; Rauwerda, G.K.; van de Burgwal, M.D.; Smit, Gerardus Johannes Maria; Cardoso, João M.P.; Hübner, Michael

2011-01-01

The overall mission of the 4S project (Smart Chips for Smart Surroundings) was to define and develop efficient flexible, reconfigurable core building blocks, including the supporting tools, for future Ambient System Devices. Reconfigurability offers the needed flexibility and adaptability, it

Probing α-3(10) transitions in a voltage-sensing S4 helix.

Science.gov (United States)

Kubota, Tomoya; Lacroix, Jérôme J; Bezanilla, Francisco; Correa, Ana M

2014-09-02

The S4 helix of voltage sensor domains (VSDs) transfers its gating charges across the membrane electrical field in response to changes of the membrane potential. Recent studies suggest that this process may occur via the helical conversion of the entire S4 between α and 310 conformations. Here, using LRET and FRET, we tested this hypothesis by measuring dynamic changes in the transmembrane length of S4 from engineered VSDs expressed in Xenopus oocytes. Our results suggest that the native S4 from the Ciona intestinalis voltage-sensitive phosphatase (Ci-VSP) does not exhibit extended and long-lived 310 conformations and remains mostly α-helical. Although the S4 of NavAb displays a fully extended 310 conformation in x-ray structures, its transplantation in the Ci-VSP VSD scaffold yielded similar results as the native Ci-VSP S4. Taken together, our study does not support the presence of long-lived extended α-to-310 helical conversions of the S4 in Ci-VSP associated with voltage activation. Copyright © 2014 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Invariant differential operators and characters of the AdS4 algebra

International Nuclear Information System (INIS)

Dobrev, V K

2006-01-01

The aim of this paper is to apply systematically to AdS 4 some modern tools in the representation theory of Lie algebras which are easily generalized to the supersymmetric and quantum group settings and necessary for applications to string theory and integrable models. Here we introduce the necessary representations of the AdS 4 algebra and group. We give explicitly all singular (null) vectors of the reducible AdS 4 Verma modules. These are used to obtain the AdS 4 invariant differential operators. Using this we display a new structure-a diagram involving four partially equivalent reducible representations one of which contains all finite-dimensional irreps of the AdS 4 algebra. We study in more detail the cases involving UIRs, in particular, the Di and the Rac singletons, and the massless UIRs. In the massless case, we discover the structure of sets of 2s 0 - 1 conserved currents for each spin s 0 UIR, s 0 = 1, 3/2,.... All massless cases are contained in a one-parameter subfamily of the quartet diagrams mentioned above, the parameter being the spin s 0 . Further we give the classification of the so(5,C) irreps presented in a diagrammatic way which makes easy the derivation of all character formulae. The paper concludes with a speculation on the possible applications of the character formulae to integrable models

Antiviral and antifungal activity of some dermaseptin S4 analogues ...

African Journals Online (AJOL)

Dermaseptins are peptides found in skin secretions of Phyllomedusinae frogs. These peptides exert lytic action on various microorganisms, and do not have a considerable haemolytic effect apart from dermaseptin S4 (DS-S4) that presents a potent cytotoxic effect. This investigation was an attempt to synthesize several ...

Interaction of integrin β4 with S1P receptors in S1P- and HGF-induced endothelial barrier enhancement.

Science.gov (United States)

Ni, Xiuqin; Epshtein, Yulia; Chen, Weiguo; Zhou, Tingting; Xie, Lishi; Garcia, Joe G N; Jacobson, Jeffrey R

2014-06-01

We previously reported sphingosine 1-phosphate (S1P) and hepatocyte growth factor (HGF) augment endothelial cell (EC) barrier function and attenuate murine acute lung inury (ALI). While the mechanisms underlying these effects are not fully understood, S1P and HGF both transactivate the S1P receptor, S1PR1 and integrin β4 (ITGB4) at membrane caveolin-enriched microdomains (CEMs). In the current study, we investigated the roles of S1PR2 and S1PR3 in S1P/HGF-mediated EC signaling and their associations with ITGB4. Our studies confirmed ITGB4 and S1PR2/3 are recruited to CEMs in human lung EC in response to either S1P (1 µM, 5 min) or HGF (25 ng/ml, 5 min). Co-immunoprecipitation experiments identified an S1P/HGF-mediated interaction of ITGB4 with both S1PR2 and S1PR3. We then employed an in situ proximity ligation assay (PLA) to confirm a direct ITGB4-S1PR3 association induced by S1P/HGF although a direct association was not detectable between S1PR2 and ITGB4. S1PR1 knockdown (siRNA), however, abrogated S1P/HGF-induced ITGB4-S1PR2 associations while there was no effect on ITGB4-S1PR3 associations. Moreover, PLA confirmed a direct association between S1PR1 and S1PR2 induced by S1P and HGF. Finally, silencing of S1PR2 significantly attenuated S1P/HGF-induced EC barrier enhancement as measured by transendothelial resistance while silencing of S1PR3 significantly augmented S1P/HGF-induced barrier enhancement. These results confirm an important role for S1PR2 and S1PR3 in S1P/HGF-mediated EC barrier responses that are associated with their complex formation with ITGB4. Our findings elucidate novel mechanisms of EC barrier regulation that may ultimately lead to new therapeutic targets for disorders characterized by increased vascular permeability including ALI. © 2013 Wiley Periodicals, Inc.

Fabrication and characterization of nanostructured Fe3S4, an isostructural compound of half-metallic Fe3O4

KAUST Repository

Li, Peng; Xia, Chuan; Zhang, Qiang; Guo, Zaibing; Cui, Wenyao; Bai, Haili; Alshareef, Husam N.; Zhang, Xixiang

2015-01-01

High-purity, well-crystallized spinel Fe3S4 nanoplatelets were synthesized by the hydrothermal method, and the saturation magnetic moment of Fe3S4 was measured at 1.83 μB/f.u. The temperature-dependent resistivity of Fe3S4 was metallic

4p-5s transitions in In XIII, In XIV and In XV

International Nuclear Information System (INIS)

Carroll, P.K.; Costello, J.T.; O'Sullivan, G.

1986-01-01

The spectrum of an indium plasma produced by a 1.5 J, 25 ns ruby laser was recorded in the XUV. At wavelengths below 100 A, the spectrum is dominated by 4p-5s transitions in a number of ion stages. Many lines arising from 4p 6 4d-4p 5 4d5s, 4p 6 -4p 5 5s and 4p 5 -4p 4 5s transitions in In XIII, In XIV and In XV have been identified by isoelectronic extrapolation and Dirac-Fock calculations. (orig.)

Relaxation of magnetization in spinel CuCrZrS4

International Nuclear Information System (INIS)

Ito, Masakazu; Furuta, Tatsuya; Terada, Norio; Ebisu, Shuji; Nagata, Shoichi

2012-01-01

We studied time t dependence of magnetization M(t) of thiospinel CuCrZrS 4 which has a spin-glass freezing. The relaxation of M is observed below T f ≃6K and shows a logarithmic time dependence. This means that a relaxation time τ of CuCrZrS 4 is distributed in a wide time range. Randomness of an arrangement of the Cr and Zr ions in CuCrZrS 4 probably gives rise to a distribution of τ. Temperature T dependence of magnetic viscosity β(T) is understood by a conventional after-effect model with a box-type distribution function of τ.

Application And Implication Of Nanomaterials In The Environment: An Overview Of Current Research At The Environmental Protection Agency (Romania)

Science.gov (United States)

The purpose of this presentation is to teach a course on analytical techniques, quality assurance, environmental research protocols, and basic soil environmental chemistry at the Environmental Health Center and Babes Bolyai University in Cluj, Romania. FOR FURTHER INFORMATI...

Laser and radiofrequency spectroscopy of the 4d55s5Dsub(0,1,2,3,4) and 4d45s5p5Psub(1,2,3) states in Mo I: Hyperfine structure and isotope shifts

International Nuclear Information System (INIS)

Olsson, T.; Fraenkel, L.; Lindgren, I.; Nyberg, A.; Robertsson, L.; Rosen, A.

1986-01-01

A series of experiments has been performed to determine the hyperfine structure in the metastable 4d 5 5s 5 Dsub(1,2,3,4) states of Mo I by means of the laser radiofrequency double-resonance technique. Furthermore, hyperfine structure splittings and isotope shifts in seven optical transitions connecting the 4d 5 5s 5 Dsub(0,1,2,3,4) and the 4d 4 5s5p 5 Psub(1,2,3) states were resolved with the high-resolution laser spectroscopy technique. Radial hyperfine structure parameters are deduced for the effective operator within the 5 D states using the configurations 4d 4 5s 2 , 4d 5 5s and 4d 6 as a model space. The isotope shifts are also discussed, utilizing an effective operator, with particular emphasis on the J dependence. (orig.)

George Sand en de Nederlandse negentiende-eeuwse pers. Het belang van computerondersteund tijdschriftonderzoek

Directory of Open Access Journals (Sweden)

Suzan van Dijk

2010-09-01

Full Text Available  Twentieth-century book and literary historians have tended to seriously underestimate women‟s participation in the nineteenth-century literary field. Thanks to different digital and online tools it becomes now possible to get a better understanding of their presence as authors. This is demonstrated in the present article, where the case „George Sand as received in nineteenth-century Netherlands‟ is used as an example. In particular it is shown that there has been, up to recently, too much reliance on critical articles published in the nineteenth-century literary press. Dutch critics publishing negative comments on George Sand‟s works will most often have had the intention to combat her actual success with Dutch readers and her possible influence on them. And those literary reviews refraining from publishing articles on her work show, by the frequency of their mentioning Sand‟s name, that she was in fact very present in the cultural repertoire of the nineteenth-century Netherlands.

Chemical and electrical properties of (NH4)2S passivated GaSb surface

International Nuclear Information System (INIS)

Tao Dongyan; Cheng Yu; Liu Jingming; Su Jie; Liu Tong; Yang Fengyun; Wang Fenghua; Cao Kewei; Dong Zhiyuan; Zhao Youwen

2015-01-01

The surface chemical properties of gallium antimonide (GaSb) after ammonium sulfide ((NH 4 ) 2 S) solution passivation have been studied by X-ray photoelectron spectroscopy (XPS), time of flight secondary ion mass spectroscopy (TOF-SIMS) and I–V measurement. An advantage of neutral (NH 4 ) 2 S + S solution over pure (NH 4 ) 2 S solution and alkaline (NH 4 ) 2 S + S solution has been found in the ability to passivate the GaSb surface by contrast and comparison. It has been found that alkaline (NH 4 ) 2 S + S solution passivation effectively removes oxides of the GaSb surface and forms sulfide products to improve device performance. TOF-SIMS complementally demonstrates that pure (NH 4 ) 2 S passivation did form sulfide products, which are too soluble to really exist. The lowest roughness determined using a 3D optical profilometer and the highest improved SBD quality proved that neutral (NH 4 ) 2 S + S solution passivation worked much better in improving the surface properties of GaSb. (paper)

Effects of Zb states and bottom meson loops on ϒ (4 S )→ϒ (1 S ,2 S )π+π- transitions

Science.gov (United States)

Chen, Yun-Hua; Cleven, Martin; Daub, Johanna T.; Guo, Feng-Kun; Hanhart, Christoph; Kubis, Bastian; Meißner, Ulf-G.; Zou, Bing-Song

2017-02-01

We study the dipion transitions ϒ (4 S )→ϒ (n S )π+π- (n =1 ,2 ) . In particular, we consider the effects of the two intermediate bottomoniumlike exotic states Zb(10610 ) and Zb(10650 ) as well as bottom meson loops. The strong pion-pion final-state interactions, especially including channel coupling to K K ¯ in the S wave, are taken into account model independently by using dispersion theory. Based on a nonrelativistic effective field theory we find that the contribution from the bottom meson loops is comparable to those from the chiral contact terms and the Zb-exchange terms. For the ϒ (4 S )→ϒ (2 S )π+π- decay, the result shows that including the effects of the Zb exchange and the bottom meson loops can naturally reproduce the two-hump behavior of the π π mass spectra. Future angular distribution data are decisive for the identification of different production mechanisms. For the ϒ (4 S )→ϒ (1 S )π+π- decay, we show that there is a narrow dip around 1 GeV in the π π invariant mass distribution, caused by the final-state interactions. The distribution is clearly different from that in similar transitions from lower ϒ states, and needs to be verified by future data with high statistics. Also we predict the decay width and the dikaon mass distribution of the ϒ (4 S )→ϒ (1 S )K+K- process.

Investigating the role of (2S,4R)-4-hydroxyproline in elastin model peptides

DEFF Research Database (Denmark)

Bochicchio, Brigida; Laurita, Alessandro; Heinz, Andrea

2013-01-01

Post-translational modifications play a key role in defining the biological functions of proteins. Among them, the hydroxylation of proline producing the (2S,4R)-4-hydroxyproline (Hyp) is one of the most frequent modifications observed in vertebrates, being particularly abundant in the proteins o...

Steam producing plant concept of 4S for oil sand extraction

International Nuclear Information System (INIS)

Matsuyama, Shinichiro; Nishiguchi, Youhei; Sakashita, Yoshiaki; Kasuga, Shoji; Kawashima, Masatoshi

2009-01-01

Plant concept of small fast reactor '4S' applying to continuous steam production for recovery of crude oil from oil sands was investigated. Assuming typical steam assisted gravity drainage (SAGD) plant whose production scale is 120,000 barrels per day of a crude oil, concept of nuclear steam supply system consisting of eight reactor modules for steam production and three reactor modules for electric generation of the 4S with a thermal rating of 135 MWt was established without any essential or significant design change from the preceding 4S with a thermal rating of 30 MWt. The 4S, provided for an oil sand extraction, will reduce greenhouse gas emission significantly, and has not much burden for development and licensing and has economic competitiveness. (author)

Checklist and Bibliography of Benthic Marine Macroalgae Recorded from Northern Australia. I. Rhodophyta,

Science.gov (United States)

1984-01-01

Basson, P.W. (1979). "Marine algae of the Arabian Qilf coast of Saudi Arabia. II." Botanica mar., 22, 65-82. Belanger, C., Dory de Saint Vincent, J.B. and...Cook Island". Botanica mr., 20, 161-166. Chiang, Y.M. (1970). "Morphological studies of red algae of the family Cryptonemiaceas." Univ. Calif. Pubis Bot...western Indian Ocean." Botanica mar., 25, 401-444. 83 Parke, M. and Dixon, P.S. (1976). "Check-list of British marine algae - third revision." J. mar

Methods of using (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid

Energy Technology Data Exchange (ETDEWEB)

Silverman, Richard B; Dewey, Stephen L; Miller, Steven

2015-03-03

(1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid also known as CPP-115 or its pharmaceutically acceptable salts can be used to treat addiction and neurological disorders such as epilepsy without side effects such as visual field defects caused by vigabatrin (Sabril).

Reactivity of Cubane-Type [(OC)(3)MFe(3)S(4)(SR)(3)](3-) Clusters (M = Mo, W): Interconversion with Cuboidal [Fe(3)S(4)](0) Clusters and Electron Transfer.

Science.gov (United States)

Raebiger, James W.; Crawford, Charles A.; Zhou, Jian; Holm, R. H.

1997-03-12

The title clusters, several examples of which have been reported earlier, have been prepared by two different methods and subjected to structural and reactivity studies. The compounds (Et(4)N)(3)[(OC)(3)MFe(3)S(4)(Smes)(3)].MeCN (M = Mo/W) are isomorphous and crystallize in monoclinic space group P2(1)/n with a = 13.412(1)/13.297(1) Å, b = 19.0380(1)/18.9376(3) Å, c = 26.4210(1)/26.2949(1) Å, beta = 97.87(1)/97.549(1) degrees, and Z = 4. The clusters contain long M-S (2.62/2.59 Å) and M-Fe (3.22/3.19 Å) bonds, consistent with the reported structure of [(OC)(3)MoFe(3)S(4)(SEt)(3)](3-) (3). Reaction of [(OC)(3)MoFe(3)S(4)(LS(3))](3-) (7) with CO in the presence of NaPF(6) affords cuboidal [Fe(3)S(4)(LS(3))](3-) (9), also prepared in this laboratory by another route as a synthetic analogue of protein-bound [Fe(3)S(4)](0) clusters. The clusters [Fe(3)S(4)(SR)(3)](3-) (R = mes, Et), of limited stability, were generated by the same reaction. Treatment of 9 with [M(CO)(3)(MeCN)(3)] affords 7 and its M = W analogue. The clusters [(OC)(3)MFe(3)S(4)(SR)(3)](3-) form a four-member electron transfer series in which the 3- cluster can be once reduced (4-) and twice oxidized (2-, 1-) to afford clusters of the indicated charges. The correct assignment of redox couple to potential in the redox series of six clusters is presented, correcting an earlier misassignment of the redox series of 3. Carbonyl stretching frequencies are shown to be sensitive to cluster oxidation state, showing that the M sites and Fe(3)S(4) fragments are electronically coupled despite the long bond distances. (LS(3) = 1,3,5-tris((4,6-dimethyl-3-mercaptophenyl)thio)-2,4,6-tris(p-tolylthio)benzenate(3-); mes = mesityl.)

Fabrication and characterization of nanostructured Fe3S4, an isostructural compound of half-metallic Fe3O4

KAUST Repository

Li, Peng

2015-06-10

High-purity, well-crystallized spinel Fe3S4 nanoplatelets were synthesized by the hydrothermal method, and the saturation magnetic moment of Fe3S4 was measured at 1.83 μB/f.u. The temperature-dependent resistivity of Fe3S4 was metallic-like for T < 180 K: room-temperature resistivity was measured at 7.711 × 103  μΩ cm. The anomalous Hall conductivity of Fe3S4 decreased with increasing longitudinal conductivity, in sharp contrast with the accepted theory of the anomalous Hall effect in a dirty-metal regime. Furthermore, negligible spin-dependent magnetoresistance was observed. Band structure calculations confirmed our experimental observations that Fe3S4 is a metal and not a half metal as expected.

A review of cinnabar (HgS) and/or realgar (As4S4)-containing traditional medicines.

Science.gov (United States)

Liu, Jie; Wei, Li-Xin; Wang, Qi; Lu, Yuan-Fu; Zhang, Feng; Shi, Jing-Zhen; Li, Cen; Cherian, M George

2018-01-10

Herbo-metallic preparations have a long history in the treatment of diseases, and are still used today for refractory diseases, as adjuncts to standard therapy, or for economic reasons in developing countries. This review uses cinnabar (HgS) and realgar (As 4 S 4 ) as mineral examples to discuss their occurrence, therapeutic use, pharmacology, toxicity in traditional medicine mixtures, and research perspectives. A literature search on cinnabar and realgar from PubMed, Chinese pharmacopeia, Google and other sources was carried out. Traditional medicines containing both cinnabar and realgar (An-Gong-Niu-Huang Wan, Hua-Feng-Dan); mainly cinnabar (Zhu-Sha-An-Shen Wan; Zuotai and Dangzuo), and mainly realgar (Huang-Dai Pian; Liu-Shen Wan; Niu-Huang-Jie-Du) are discussed. Both cinnabar and realgar used in traditional medicines are subjected to special preparation procedures to remove impurities. Metals in these traditional medicines are in the sulfide forms which are different from environmental mercurials (HgCl 2 , MeHg) or arsenicals (NaAsO 2 , NaH 2 AsO 4 ). Cinnabar and/or realgar are seldom used alone, but rather as mixtures with herbs and/or animal products in traditional medicines. Advanced technologies are now used to characterize these preparations. The bioaccessibility, absorption, distribution, metabolism and elimination of these herbo-metallic preparations are different from environmental metals. The rationale of including metals in traditional remedies and their interactions with drugs need to be justified. At higher therapeutic doses, balance of the benefits and risks is critical. Surveillance of patients using these herbo-metallic preparations is desired. Chemical forms of mercury and arsenic are a major determinant of their disposition, efficacy and toxicity, and the use of total Hg and As alone for risk assessment of metals in traditional medicines is insufficient. Copyright © 2017 Elsevier B.V. All rights reserved.

Factorized tree-level scattering in AdS4 x CP3

International Nuclear Information System (INIS)

Kalousios, Chrysostomos; Vergu, C.; Volovich, Anastasia

2009-01-01

AdS 4 /CFT 3 duality relating IIA string theory on AdS 4 x CP 3 to N = 6 superconformal Chern-Simons theory provides an arena for studying aspects of integrability in a new potentially exactly solvable system. In this paper we explore the tree-level worldsheet scattering for strings on AdS 4 x CP 3 . We compute all bosonic four-, five- and six-point amplitudes in the gauge-fixed action and demonstrate the absence of particle production.

Short-range order parameters in amorphous YBaS4X7(X-S, SE, TE) films

International Nuclear Information System (INIS)

Hajiyev, E.S.

2005-01-01

Full text : Electron scattering intensity curves from amorphous YbAs 4 X 7 (X-S, SE, TE) films have ben obtained by the transmission electron diffraction (TED) method with rotation sector before screen up. The energy of electrons was 100 keV. Amorphous samples were crystallized and the composition of the products were measured by TED. The atomic radial distribution function has been calculated by the Fourier synthesis of intensities in the TED of amorphous YbAs 4 X 7 (X-S, SE, TE) films. The interatomic average distances of As - S (Se, Te) and As-Yb + 2 and partial coordination numbers have been estimated in these thilms. Based on these numbers, chemical orders in these films differ. This difference is due to differing topological order in the amorphous YbAs 4 X 7 (X-S, SE, TE) films

Disproportionation and thermochemical sulfate reduction reactions in S-H20-Ch4 and S-D2O-CH4 systems from 200 to 340 °C at elevated pressures

Science.gov (United States)

Yuan, Shunda; Chou, I-Ming; Burruss, Robert A.

2013-01-01

Elemental sulfur, as a transient intermediate compound, by-product, or catalyst, plays significant roles in thermochemical sulfate reduction (TSR) reactions. However, the mechanisms of the reactions in S-H2O-hydrocarbons systems are not clear. To improve our understanding of reaction mechanisms, we conducted a series of experiments between 200 and 340 °C for S-H2O-CH4, S-D2O-CH4, and S-CH4-1m ZnBr2 systems in fused silica capillary capsules (FSCC). After a heating period ranging from 24 to 2160 hours (hrs), the quenched samples were analyzed by Raman spectroscopy. Combined with the in situ Raman spectra collected at high temperatures and pressures in the S-H2O and S-H2O-CH4 systems, our results showed that (1) the disproportionation of sulfur in the S-H2O-CH4 system occurred at temperatures above 200 °C and produced H2S, SO42-, and possibly trace amount of HSO4-; (2) sulfate (and bisulfate), in the presence of sulfur, can be reduced by methane between 250 and 340 °C to produce CO2 and H2S, and these TSR temperatures are much closer to those of the natural system (2O-CH4 system may take place simultaneously, with TSR being favored at higher temperatures; and (4) in the system S-D2O-CH4, both TSR and the competitive disproportionation reactions occurred simultaneously at temperatures above 300 °C, but these reactions were very slow at lower temperatures. Our observation of methane reaction at 250 °C in a laboratory time scale suggests that, in a geologic time scale, methane may be destroyed by TSR reactions at temperatures > 200 °C that can be reached by deep drilling for hydrocarbon resources.

Cfr and RlmN contain a single [4Fe-4S] cluster, which directs two distinct reactivities for S-adenosylmethionine: methyl transfer by SN2 displacement and radical generation.

Science.gov (United States)

Grove, Tyler L; Radle, Matthew I; Krebs, Carsten; Booker, Squire J

2011-12-14

The radical SAM (RS) proteins RlmN and Cfr catalyze methylation of carbons 2 and 8, respectively, of adenosine 2503 in 23S rRNA. Both reactions are similar in scope, entailing the synthesis of a methyl group partially derived from S-adenosylmethionine (SAM) onto electrophilic sp(2)-hybridized carbon atoms via the intermediacy of a protein S-methylcysteinyl (mCys) residue. Both proteins contain five conserved Cys residues, each required for turnover. Three cysteines lie in a canonical RS CxxxCxxC motif and coordinate a [4Fe-4S]-cluster cofactor; the remaining two are at opposite ends of the polypeptide. Here we show that each protein contains only the one "radical SAM" [4Fe-4S] cluster and the two remaining conserved cysteines do not coordinate additional iron-containing species. In addition, we show that, while wild-type RlmN bears the C355 mCys residue in its as-isolated state, RlmN that is either engineered to lack the [4Fe-4S] cluster by substitution of the coordinating cysteines or isolated from Escherichia coli cultured under iron-limiting conditions does not bear a C355 mCys residue. Reconstitution of the [4Fe-4S] cluster on wild-type apo RlmN followed by addition of SAM results in rapid production of S-adenosylhomocysteine (SAH) and the mCys residue, while treatment of apo RlmN with SAM affords no observable reaction. These results indicate that in Cfr and RlmN, SAM bound to the unique iron of the [4Fe-4S] cluster displays two reactivities. It serves to methylate C355 of RlmN (C338 of Cfr), or to generate the 5'-deoxyadenosyl 5'-radical, required for substrate-dependent methyl synthase activity. © 2011 American Chemical Society

ZnS-Passivated CdSe/CdS Co-sensitized Mesoporous Zn2SnO4 Based Solar Cells

International Nuclear Information System (INIS)

Kim, Kyungho; Park, Ji Eun; Park, Eun Su; Park, Yun Chang; Kim, Joosun; Im, Chan; Lee, Man-Jong

2014-01-01

Graphical abstract: - Highlights: • Mesoporous Zn 2 SnO 4 sensitized by CdSe/CdS QDs were synthesized via a two-step sequential process. • Assembled QDs were characterized by HRTEM and STEM mapping. • Efficiency increase in CdSe/CdS co-sensitized Zn 2 SnO 4 DSSCs is discussed. • The role of ZnS passivation layer is discussed by impedance spectroscopy. - Abstract: CdS and CdSe/CdS quantum dot (QD) sensitizers were assembled onto mesoporous ternary Zn 2 SnO 4 photoanodes using a two-step sequential process of successive ionic layer absorption and reaction (SILAR) and chemical bath deposition (CBD) for QD-cosensitized solar cell applications. The assembled CdS and CdSe QDs were observed using high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM), high-resolution TEM (HRTEM), and STEM/energy-dispersive X-ray spectroscopy (EDS) elemental mapping. CdSe/CdS cosensitized Zn 2 SnO 4 -based cells showed a higher absorption onset position, a stepwise band-edge level alignment, and, thereby, an improved power conversion efficiency (PCE) of 1.628% under one-sun conditions, which is the best result obtained using mesoporous Zn 2 SnO 4 reported to date. In addition, the effect of a ZnS passivation layer on the photovoltaic performance and aging behavior has been investigated. Electrochemical impedance spectroscopy (EIS) showed that the main role of the ZnS layer is to enhance the aging behavior of the CdSe/CdS/Zn 2 SnO 4 cells by improving the electron lifetime and charge recombination

Electronic properties of GaV4S8: A percolation approach

Indian Academy of Sciences (India)

This statement is strongly supported by the calculated band- width per cluster in GaV4S8 .... site in GaV4S8 are the same because of the identical chemical composition. 3.2 Resistivity. The resistivity of .... One of the authors (S Hansda) acknowledges UGC, New Delhi, India for the financial support through Rajiv Gandhi ...

Eisenstein ja gangster Mishka / Vaapo Vaher

Index Scriptorium Estoniae

Vaher, Vaapo, 1945-

2005-01-01

Isaak Babeli stsenaariumi järgi, mis põhines kirjaniku enda jutustusel, valmis 1927.a. mängufilm "Benja Krik", mille režissöör oli Vladimir Vilner, kes asendas siin tööst eemaldunud Sergei Eisensteini

(4bS,8aS-1-Isopropyl-4b,8,8-trimethyl-4b,5,6,7,8,8a,9,10-octahydrophenanthren-2-yl acetate

Directory of Open Access Journals (Sweden)

Radouane Oubabi

2014-03-01

Full Text Available The hemisynthesis of the title compound, C22H32O2, was carried out through direct acetylation reaction of the naturally occurring diterpene totarol [systematic name: (4bS,8aS-4b,8,8-trimethyl-1-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthren-2-ol]. The molecule is built up from three fused six membered rings, one saturated and two unsaturated. The central unsaturated ring has a half-chair conformation, whereas the other unsaturated ring displays a chair conformation. The absolute configuration is deduced from the chemical pathway. The value of the Hooft parameter [−0.10 (6] allowed this absolute configuration to be confirmed.

The S100A4 Oncoprotein Promotes Prostate Tumorigenesis in a Transgenic Mouse Model

DEFF Research Database (Denmark)

Siddique, Hifzur R; Adhami, Vaqar M; Parray, Aijaz

2013-01-01

earlier showed that S100A4 expression progressively increases in prostatic tissues with the advancement of prostate cancer (CaP) in TRAMP, an autochthonous mouse model. To study the functional significance of S100A4 in CaP, we generated a heterozygously deleted S100A4 (TRAMP/S100A4(+/-)) genotype...... (intracellular and extracellular) forms. We observed that 1) the growth-promoting effect of S100A4 is due to its activation of NFκB, 2) S100A4-deficient tumors exhibit reduced NFκB activity, 3) S100A4 regulates NFκB through the RAGE receptor, and 4) S100A4 and RAGE co-localize in prostatic tissues of mice......S100A4, a calcium-binding protein, is known for its role in the metastatic spread of tumor cells, a late event of cancer disease. This is the first report showing that S100A4 is not merely a metastatic protein but also an oncoprotein that plays a critical role in the development of tumors. We...

Determination of diffusion coefficients for sulfide ions in solid electrolytes on the basis of BaSm2S4 and CaGd2S4

International Nuclear Information System (INIS)

Yurlov, I.S.; Ushakova, Yu.N.; Medvedeva, O.V.; Kalinina, L.A.; Shirokova, G.I.; Ananchenko, B.A.

2007-01-01

Coefficients of self-diffusion and coefficients of diffusion of the sulfur ion in solid electrolytes BaSm 2 S 4 and CaGd 2 S 4 are determined with recourse to methods of conductometry and potentiostatic chronoamperometry. A vacancy mechanism for the defect formation in solid solutions on the basis of barium thiosamarate and calcium thiogadolynate is proposed [ru

Dimethyl 2,2′-[Carbonylbis(azanediyl](2S,2′S-bis[3-(4-hydroxyphenylpropanoate

Directory of Open Access Journals (Sweden)

Raffaella Mancuso

2018-02-01

Full Text Available The thus-far unknown ureic derivative dimethyl 2,2′-[carbonylbis(azanediyl](2S,2′S-bis[3-(4-hydroxyphenylpropanoate] has been efficiently synthesized by enantiospecific oxidative carbonylation of readily available l-tyrosine methyl ester, using a very simple catalytic system (PdI2 in conjunction with KI under relatively mild conditions (100 °C for 5 h in DME as the solvent and under 20 atm of a 4:1 mixture CO-air.

22 CFR 127.4 - Authority of U.S. Immigration and Customs Enforcement and U.S. Customs and Border Protection...

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Authority of U.S. Immigration and Customs Enforcement and U.S. Customs and Border Protection officers. 127.4 Section 127.4 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS VIOLATIONS AND PENALTIES § 127.4 Authority of U.S...

Lighting in the health care sector; Verlichting in de zorg

Energy Technology Data Exchange (ETDEWEB)

Visser, R. [Grontmij, Amersfoort (Netherlands)

2009-02-15

The importance of light for people's health and welfare attracts frequent attention, not only the professional press but also in countless articles in newspapers and news magazines. Insufficient illumination can upset the biological clock and may even cause depression. In principle this applies to anyone who has to stay indoors all day or nearly all day; in the case of care homes it affects residents who have no regular opportunity to sit at a window, for example those who are bedridden. Research indicates that we need a minimum daily portion of daylight or of artificial light with similar qualities as daylight. This is also of great importance to night workers. [Dutch] Niet alleen in de vakpers, maar ook in tal van dag- en weekbladen, wordt regelmatig het belang van licht voor het welzijn en de gezondheid van de mens aan de orde gesteld. Gebrek aan voldoende licht kan het bioritme verstoren en zelfs leiden tot depressie. Dat geldt in principe voor alle mensen die om wat voor redenen dan ook de hele dag of nagenoeg de hele dag binnen moeten blijven. In zorginstellingen is dit vooral van toepassing voor degenen die zich niet regelmatig direct achter het ream kunnen bevinden, zoals mensen die bedlegering zijn. Want door onderzoek is gebleken dat we elke dag een voldoende portie daglicht nodig hebben of licht met overeenkomstige kwaliteiten als daglicht. Voor mensen die 's nachts moeten werken is het laatstgenoemde ook van groot belang.

The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating.

Directory of Open Access Journals (Sweden)

Chai Ann Ng

Full Text Available Human ether-à-go-go-related gene (hERG K(+ channels have unusual gating kinetics. Characterised by slow activation/deactivation but rapid inactivation/recovery from inactivation, the unique gating kinetics underlie the central role hERG channels play in cardiac repolarisation. The slow activation and deactivation kinetics are regulated in part by the S4-S5 linker, which couples movement of the voltage sensor domain to opening of the activation gate at the distal end of the inner helix of the pore domain. It has also been suggested that cytosolic domains may interact with the S4-S5 linker to regulate activation and deactivation kinetics. Here, we show that the solution structure of a peptide corresponding to the S4-S5 linker of hERG contains an amphipathic helix. The effects of mutations at the majority of residues in the S4-S5 linker of hERG were consistent with the previously identified role in coupling voltage sensor movement to the activation gate. However, mutations to Ser543, Tyr545, Gly546 and Ala548 had more complex phenotypes indicating that these residues are involved in additional interactions. We propose a model in which the S4-S5 linker, in addition to coupling VSD movement to the activation gate, also contributes to interactions that stabilise the closed state and a separate set of interactions that stabilise the open state. The S4-S5 linker therefore acts as a signal integrator and plays a crucial role in the slow deactivation kinetics of the channel.

Three-spin Strings on AdS_5 x S^5 from N=4 SYM

DEFF Research Database (Denmark)

Kristjansen, C.

2004-01-01

Using the integrable spin chain picture we study the one-loop anomalous dimension of certain single trace scalar operators of N=4 SYM expected to correspond to semi-classical string states on AdS_5 x S^5 with three large angular momenta (J_1,J_2,J_3) on S^5. In particular, we investigate the anal......Using the integrable spin chain picture we study the one-loop anomalous dimension of certain single trace scalar operators of N=4 SYM expected to correspond to semi-classical string states on AdS_5 x S^5 with three large angular momenta (J_1,J_2,J_3) on S^5. In particular, we investigate...... the analyticity structure encoded in the Bethe equations for various distributions of Bethe roots. In a certain region of the parameter space our operators reduce to the gauge theory duals of the folded string with two large angular momenta and in another region to the duals of the circular string with angular...... momentum assignment (J,J',J'), J>J'. In between we locate a critical line. We propose that the operators above the critical line are the gauge theory duals of the circular elliptic string with three different spins and support this by a perturbative calculation....

Mouse nucleolin binds to 4.5S RNAH, a small noncoding RNA

International Nuclear Information System (INIS)

Hirose, Yutaka; Harada, Fumio

2008-01-01

4.5S RNAH is a rodent-specific small noncoding RNA that exhibits extensive homology to the B1 short interspersed element. Although 4.5S RNAH is known to associate with cellular poly(A)-terminated RNAs and retroviral genomic RNAs, its function remains unclear. In this study, we analyzed 4.5S RNAH-binding proteins in mouse nuclear extracts using gel mobility shift and RNA-protein UV cross-linking assays. We found that at least nine distinct polypeptides (p170, p110, p93, p70, p48, p40, p34, p20, and p16.5) specifically interacted with 4.5S RNAHin vitro. Using anti-La antibody, p48 was identified as mouse La protein. To identify the other 4.5S RNAH-binding proteins, we performed expression cloning from a mouse cDNA library and obtained cDNA clones derived from nucleolin mRNA. We identified p110 as nucleolin using nucleolin-specific antibodies. UV cross-linking analysis using various deletion mutants of nucleolin indicated that the third of four tandem RNA recognition motifs is a major determinant for 4.5S RNAH recognition. Immunoprecipitation of nucleolin from the subcellular fractions of mouse cell extracts revealed that a portion of the endogenous 4.5S RNAH was associated with nucleolin and that this complex was located in both the nucleoplasm and nucleolus

Three new chalcohalides, Ba4Ge2PbS8Br2, Ba4Ge2PbSe8Br2 and Ba4Ge2SnS8Br2: Syntheses, crystal structures, band gaps, and electronic structures

International Nuclear Information System (INIS)

Lin, Zuohong; Feng, Kai; Tu, Heng; Kang, Lei; Lin, Zheshuai; Yao, Jiyong; Wu, Yicheng

2014-01-01

Highlights: • Three new chalcohalides: Ba 4 Ge 2 PbS 8 Br 2 , Ba 4 Ge 2 PbSe 8 Br 2 and Ba 4 Ge 2 SnS 8 Br 2 have been synthesized. • The MQ 5 Br octahedra and GeQ 4 tetrahedra form a three-dimensional framework with Ba 2+ in the channels. • Band Gaps and electronic structures of the three compounds were studied. - Abstract: Single crystals of three new chalcohalides: Ba 4 Ge 2 PbS 8 Br 2 , Ba 4 Ge 2 PbSe 8 Br 2 and Ba 4 Ge 2 SnS 8 Br 2 have been synthesized for the first time. These isostructural compounds crystallize in the orthorhombic space group Pnma. In the structure, the tetra-valent Ge atom is tetrahedrally coordinated with four Q (Q = S, Se) atoms, while the bi-valent M atom (M = Pb, Sn) is coordinated with an obviously distorted octahedron of five Q (Q = S, Se) atoms and one Br atom, showing the stereochemical activity of the ns 2 lone pair electron. The MQ 5 Br (M = Sn, Pb; Q = S, Se) distorted octahedra and the GeQ 4 (Q = S, Se) tetrahedra are connected to each other to form a three-dimensional framework with channels occupied by Ba 2+ cations. Based on UV–vis–NIR spectroscopy measurements and the electronic structure calculations, Ba 4 Ge 2 PbS 8 Br 2 , Ba 4 Ge 2 PbSe 8 Br 2 and Ba 4 Ge 2 SnS 8 Br 2 have indirect band gaps of 2.054, 1.952, and 2.066 eV respectively, which are mainly determined by the orbitals from the Ge, M and Q atoms (M = Pb, Sn; Q = S, Se)

Rebalance between 7S and 11S globulins in soybean seeds of differing protein content and 11SA4.

Science.gov (United States)

Yang, A; Yu, X; Zheng, A; James, A T

2016-11-01

Protein content and globulin subunit composition of soybean seeds affect the quality of soy foods. In this proteomic study, the protein profile of soybean seeds with high (∼45.5%) or low (∼38.6%) protein content and with or without the glycinin (11S) subunit 11SA4 was examined. 44 unique proteins and their homologues were identified and showed that both protein content and 11SA4 influenced the abundance of a number of proteins. The absence of 11SA4 exerted a greater impact than the protein content, and led to a decreased abundance of glycinin G2/A2B1 and G5/A5A4B3 subunits, which resulted in lower total 11S with a concomitant higher total β-conglycinin (7S). Low protein content was associated with higher glycinin G3/A1aB1b and lower glycinin G4/A5A4B3. Using the proteomic approach, it was demonstrated that 11SA4 deficiency induced compensatory accumulation of 7S globulins and led to a similar total abundance for 7S+11S irrespective of protein content or 11SA4. Copyright © 2016 Elsevier Ltd. All rights reserved.

Four-wave mixing and parametric four-wave mixing near the 4P-4S transition of the potassium atom

International Nuclear Information System (INIS)

Katharakis, M; Merlemis, N; Serafetinides, A; Efthimiopoulos, T

2002-01-01

Potassium 4S 1/2 -6S 1/2 two-photon excitation initiates the emission of several internally generated photons. For the first time two emission lines, one close to and one below the potassium 4P 3/2 level, are reported for low pumping intensity. Radiation emitted below the 4P 3/2 level is due to a parametric four-wave mixing process that uses the photons emitted at the 5P 3/2 -4S 1/2 transition and a two-step four-wave mixing process generates the line emitted close to the 4P 3/2 level

Heat capacity measurement of CeNbO4(s)

International Nuclear Information System (INIS)

Bhojane, S.M.; Kulkarni, Jayanthi; Kulkarni, S.G.

2012-01-01

Molar heat capacity of CeNbO 4 (s) was determined using differential scanning calorimeter in the temperature range of 550 to 900 K. The molar heat capacity values were least squares analysed and the dependence of molar heat capacity with temperature for CeNbO 4 (s) can be given as, J K -1 mol -1 = 94.7320 + 0.0852T-1.6073 x 10 6 T -2 (550≤T(K)≤900) Cerium is commonly used as an inactive analogue to plutonium; also it is an important fission product with moderate yield. Various Nb alloys are used as cladding material in nuclear industry. Hosts of thermodynamic data are needed to understand the various phenomena that occur in a nuclear reactor. In the present study, the molar heat capacity of CeNbO 4 (s) has been determined using high temperature differential scanning calorimeter in temperature range 550 to 900 K. This is one of the important compounds in the ternary system of Ce-Nb-O

Empty 4f states in TmS

International Nuclear Information System (INIS)

Wachter, P.; Grioni, M.

1998-01-01

The reflectivity of TmS single crystals has been measured between 2 meV and 12 eV at room temperature and at 6 K. Besides 3p 6 -5d interband transitions a plasma edge due to free carriers is observed. In the middle infrared (near 50 meV) two sharp lines are found which are interpreted as transitions from the Fermi level into empty crystal field split 4f 13 states. A Bremsstrahlen isochromat spectroscopy (BIS) measurement supports the assumption that the empty 4f 13 state is close to the Fermi energy. (orig.)

Kom je buiten spelen: een advies over onderzoek naar de invloed van natuur op de gezondheid van kinderen

NARCIS (Netherlands)

Berg, van den A.E.

2007-01-01

In dit advies wordt op systematische wijze nagegaan wat de mate van bewijskracht is voor de breed gedeelde veronderstelling dat contact met natuur van belang is voor de gezondheid en het welzijn van kinderen.

Supersymmetric extension of Hopf maps: N = 4 {sigma}-models and the S{sup 3} {yields} S{sup 2} fibration

Energy Technology Data Exchange (ETDEWEB)

Carvalho, L. Faria; Toppan, F., E-mail: leofc@cbpf.b, E-mail: toppan@cbpf.b [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil); Kuznetsova, Z., E-mail: zhanna.kuznetsova@ufabc.edu.b [Universidade Federal do ABC (UFABC), Santo Andre, SP (Brazil)

2009-07-01

We discuss four off-shell N = 4 D = 1 supersymmetry transformations, their associated one-dimensional -models and their mutual relations. They are given by I - the (4, 4){sub lin} linear 'root' supermultiplet (supersymmetric extension of R{sup 4}), II - the (3, 4, 1){sub lin} linear supermultiplet (supersymmetric extension of R3), III - the (3, 4, 1){sub nl} non-linear supermultiplet living on S{sup 3} and IV - the (2, 4, 2){sub nl} non-linear supermultiplet living on S{sup 2}. The I {yields} II map is the supersymmetric extension of the R4 {yields} R3 bilinear map, while the II {yields} IV map is the supersymmetric extension of the S{sup 3} {yields} S{sup 2} first Hopf fibration. The restrictions on the S{sup 3}, S{sup 2} spheres are expressed in terms of the stereo graphic projections. The non-linear supermultiplets, whose super transformations are local differential polynomials, are not equivalent to the linear supermultiplets with the same field content. The -models are determined in terms of an unconstrained pre potential of the target coordinates. The Uniformization Problem requires solving an inverse problem for the pre potential. The basic features of the supersymmetric extension of the second and third Hopf maps are briefly sketched. Finally, the Schur's lemma (i.e. the real, complex or quaternionic property) is extended to all minimal linear supermultiplets up to N {<=} 8. (author)

Entanglement entropy and duality in AdS4

Directory of Open Access Journals (Sweden)

Ioannis Bakas

2015-07-01

Full Text Available Small variations of the entanglement entropy δS and the expectation value of the modular Hamiltonian δE are computed holographically for circular entangling curves in the boundary of AdS4, using gravitational perturbations with general boundary conditions in spherical coordinates. Agreement with the first law of thermodynamics, δS=δE, requires that the line element of the entangling curve remains constant. In this context, we also find a manifestation of electric–magnetic duality for the entanglement entropy and the corresponding modular Hamiltonian, following from the holographic energy–momentum/Cotton tensor duality.

Currents of thermally stimulated depolarization in CaIn{sub 2}S{sub 4} single crystals; Toki termostimulirovannoj depolyarizatsii v monokristallakh CaIN{sub 2}S{sub 4}

Energy Technology Data Exchange (ETDEWEB)

Tagiev, B G; Tagiev, O B; Dzhabbarov, R B; Musaeva, N N [AN Azerbajdzhanskoj SSR, Baku (Azerbaijan). Inst. Fiziki

1996-10-01

The results of investigation into currents of thermally stimulated depolarization in CaIn{sub 2}S{sub 4} monocrystals are presented for the first time. Spectra of thermally stimulated depolarization for In-CaIn{sub S4}-In structures are measured under T=99 K at various rates of heat, times of polarization and times of expectation following switching off of electrical field up to beginning of measurements of shorting. The main parameters of capture cross section, partial factor, concentration of traps, are determined. It is determined that one may observed a biomolecular mechanism with a strong secondary capture in CaIn{sub 2}S{sub 4} monocrystals. 9 refs.; 4 figs.

Collision broadening and shift of the potassium 4P-7S and 4P-5D lines by argon

International Nuclear Information System (INIS)

Hohimer, J.P.

1981-01-01

A two-step laser excitation technique has been used to investigate the collisional broadening and shift of excited-state potassium transitions. Values for the argon collisional broadening and shift constants for the potassium 4p-7s and 4p-5d transitions were determined from line shapes for argon pressures up to 100 Torr. The values of these constants (in units of 10 -9 rad s -1 atom -1 cm 3 ) are (4P/sub 1/2/-7S/sub 1/2/): γ=11.60 +- 0.07, β=-6.68 +- 0.11; (4P/sub 3/2/-7S/sub 1/2/): γ=11.49 +- 0.15, β=-6.82 +- 0.14; (4P/sub 1/2/-5D/sub 3/2/): γ=8.64 +- 0.07, β=-4.62 +- 0.04; (4P/sub 3/2/-5D/sub 3/2/): γ=8.58 +- 0.10, β=-3.49 +- 0.32; (4P/sub 3/2/-5D/sub 5/2/): γ=9.13 +- 0.10, β=-4.73 +- 0.09. These broadening and shift constants are interpreted in terms of a Lennard-Jones interaction potential

The perturbative construction of Symanzik's improved action for [Phi][sup 4][sub 4] and QED[sub 4

Energy Technology Data Exchange (ETDEWEB)

Keller, G. (Max-Planck-Inst. fuer Physik, Werner-Heisenberg-Inst., Muenchen (Germany))

1993-08-01

For the perturbative Euclidean massive [Phi][sup 4][sub 4] and QED[sub 4] (with a small photon mass) an explicit construction of Symanzik's improved action is presented. It is established rigorously that all the Green functions exhibit improved convergence as the momentum space UV cutoff is sent to infinity. These results are obtained by an application of the powerful yet technically simple flow equation method. (orig.)

Kirjanik ja pasatornaado I / Tiit Aleksejev

Index Scriptorium Estoniae

Aleksejev, Tiit, 1968-

2008-01-01

Vene kodusõja kajastamisest 1920. aastate nõukogude proosas. Käsitletakse Isaak Babeli novellikogu "Ratsaarmee" (tõlkinud Olev Jõgi. Tallinn : Eesti Raamat, 1977), Boriss Lavrenjovi jutustust "Neljakümne esimene" (tõlkinud Jüri Karindi. Tallinn : Eesti Raamat, 1975), Viktor Kini jutustust "Valgete tagalas" (tõlkinud Jüri Ojamaa. Tallinn : Eesti Raamat, 1978), Hubert Minagrelli jutustust "Neli sõdurit" (pr. k. "Quatre soldats"), Andrei Platonovi novelli "Inimene iseendas" (ilmunud raamatus "Meistri saamine" / tõlkinud Virve Krimm. Tallinn : Eesti Raamat, 1979) ja romaani "Tševengur" (ilmunud raamatus "Tševengur. Kotlovan. Rasskazõ". Moskva, 2007), samuti ka Arkadi Gaidari loomingut

Light-cone gauge formulation for AdS4 x CP3

International Nuclear Information System (INIS)

Uvarov, D.V.

2011-01-01

We review the Type IIA superstring on the AdS 4 x CP 3 background in the k-symmetry light-cone gauge characterized by the choice of the lightlike directions from the D = 3 Minkowski boundary of AdS 4 both in the Lagrangian and Hamiltonian formulations

Biotechnologie bedreiging voor mens en natuur? Editorial.

NARCIS (Netherlands)

Asseldonk, van J.S.O.

1988-01-01

Bundeling van artikelen met aandacht voor het belang van biotechnologische projecten aan de Landbouwuniversiteit; gentransplantatie in de plantenveredeling en moleculaire veredeling; biotechnologisch onderzoek in de praktijk; voorwaarden bij biotechnologie in de veehouderij; de mogelijkheden voor

Ethics in an age of austerity: Social work and the evolving New Public Management

Directory of Open Access Journals (Sweden)

Sarah Banks

2011-05-01

benadrukt dat het van belang is om aandacht te besteden aan ethiek in de sociale sector, waarbij de auteur een eerste kader voor een situationele ethiek van sociale rechtvaardigheid schetst, die daarbij bruikbaar kan zijn.

Acoustic anisotropy of acoustooptic TI(3)AsS(4) crystals.

Science.gov (United States)

Martynyuk-Lototska, Iryna; Kushnirevych, Marian; Zapeka, Bohdan; Krupych, Oleh; Kokhan, Oleksandr; Pogodin, Artem; Peresh, Eugen; Mys, Oksana; Vlokh, Rostyslav

2015-02-20

We present comprehensive experimental measurements and analysis of anisotropy of the acoustic wave velocities for TI(3)AsS(4) crystals, including the obliquity and nonorthogonality of the acoustic waves, and the deviations from purely longitudinal and transverse polarization types. We have found that the crystals under analysis are characterized by rather low transverse wave velocities v(23) and v(32), which are both equal to 630 m/s. It is shown that the efficiency of acoustooptic (AO) interactions in TI(3)AsS(4) can be notably increased when providing anisotropic interaction with the slowest transverse acoustic wave. Under the previously mentioned conditions, the AO figure-of-merit can be estimated to be extremely high, i.e., approximately 3×10(-12) s(3)/kg.

Stereoselective synthesis of (2S,3S,4Z-4-fluoro-1,3-dihydroxy-2-(octadecanoylaminooctadec-4-ene, [(Z-4-fluoroceramide], and its phase behavior at the air/water interface

Directory of Open Access Journals (Sweden)

2008-04-01

Full Text Available BackgroundSphingolipids belong to the most important constituents of the membranes of eukaryotic cells. As intermediates in sphingolipid metabolism, sphingosine and its N-octadecanoyl-derivative, ceramide, exhibit a variety of biological functions. These compounds play a crucial role in many essential biological processes such as cell growth, cell differentiation, cell recognition and apoptosis. More specifically, sphingolipids are crucial e.g. for the function of the skin because they contribute to the formation of the water permeability barrier consisting of a highly organized multilaminar lipid matrix of free fatty acids, cholesterol and ceramides containing additional hydroxyl groups in the sphingosin part and longer fatty acid amide functions.ResultsIn a short synthetic route (2S,3S-4-fluorosphingosine and 4-fluoroceramide, the fluorinated analogues of the natural products, D-erythro-sphingosine and ceramide, have been prepared. The key step of the synthetic sequence is an asymmetric aldol reaction of (Z-2-fluorohexadec-2-enal, prepared in three steps from tetradecanal, with an enantiopure N-protected iminoglycinate. Deprotection of the imino function and reduction of the ester group led to the 4-fluorosphingosine, which on acetylation with stearoyl chloride gave 4-fluoroceramide. After careful HPLC purification of the latter compound its phase behavior was investigated by Langmuir film balance technique and compared to that of natural ceramide. While the isotherms are quite similar in shape, they differ significantly in the starting point of increasing film pressure (56 or 67 Å2/molecule and in the film collapse pressure (38 or 56 mN/m for ceramide and 4-fluoroceramide, respectively. Moreover, the hysteresis curves are very different. While consecutive isothermic compression – expansion cycles are reversible for the 4-fluoro derivative, substantial substance loss into the subphase or irreversible formation of multi-layers was observed

Frequency metrology on the 4s(2)S(1/2)-4p(2)P(1/2) transition in Ca-40(+) for a comparison with quasar data

NARCIS (Netherlands)

Wolf, A.L.; van den Berg, S.A.; Gohle, C.; Salumbides, E.J.; Ubachs, W.M.G.; Eikema, K.S.E.

2008-01-01

High accuracy frequency metrology on the 4s S 12 2 -4p P 12 2 transition in calcium ions is performed using laser cooled and crystallized ions in a linear Paul trap. Calibration is performed with a frequency comb laser, resulting in a transition frequency of f=755 222 766.2 (1.7) MHz. The accuracy

Z4-symmetric factorized S-matrix in two space-time dimensions

International Nuclear Information System (INIS)

Zamolodchikov, A.B.

1979-01-01

The factorized S-matrix with internal symmetry Z 4 is constructed in two space-time dimensions. The two-particle amplitudes are obtained by means of solving the factorization, unitarity and analyticity equations. The solution of factorization equations can be expressed in terms of elliptic functions. The S-matrix cotains the resonance poles naturally. The simple formal relation between the general factorized S-matrices and the Baxter-type lattice transfer matrices is found. In the sense of this relation the Z 4 -symmetric S-matrix corresponds to the Baxter transfer matrix itself. (orig.)

9 CFR 102.4 - U.S. Veterinary Biologics Establishment License.

Science.gov (United States)

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false U.S. Veterinary Biologics... LICENSES FOR BIOLOGICAL PRODUCTS § 102.4 U.S. Veterinary Biologics Establishment License. (a) Before a U.S. Veterinary Biologics Establishment License will be issued by the Administrator for any establishment, an...

User’s guide for MapMark4GUI—A graphical user interface for the MapMark4 R package

Science.gov (United States)

Shapiro, Jason

2018-05-29

MapMark4GUI is an R graphical user interface (GUI) developed by the U.S. Geological Survey to support user implementation of the MapMark4 R statistical software package. MapMark4 was developed by the U.S. Geological Survey to implement probability calculations for simulating undiscovered mineral resources in quantitative mineral resource assessments. The GUI provides an easy-to-use tool to input data, run simulations, and format output results for the MapMark4 package. The GUI is written and accessed in the R statistical programming language. This user’s guide includes instructions on installing and running MapMark4GUI and descriptions of the statistical output processes, output files, and test data files.

A General and Simple Diastereoselective Reduction by L-Selectride: Efficient Synthesis of Protected (4S,5S)-Dihydroxy Amides

OpenAIRE

Yin; Ye; Yu; Liu

2010-01-01

A general approach to (4S,5S)-4-benzyloxy-5-hydroxy-N-(4-methoxybenzyl) amides 10 based on a diastereoselective reduction of (5S,6RS)-6-alkyl-5-benzyloxy-6-hydroxy-2-piperidinones 6 and their tautomeric ring-opened keto amides 7 is described. The reduction with L-Selectride at -20 °C to room temperature afforded the products 10 in excellent yields and moderate to high syn-diastereoselectivities.

A general and simple diastereoselective reduction by L-Selectride: efficient synthesis of protected (4S,5S)-dihydroxy amides.

Science.gov (United States)

Yin, Bo; Ye, Dong-Nai; Yu, Kai-Hui; Liu, Liang-Xian

2010-04-16

A general approach to (4S,5S)-4-benzyloxy-5-hydroxy-N-(4-methoxybenzyl) amides 10 based on a diastereoselective reduction of (5S,6RS)-6-alkyl-5-benzyloxy-6-hydroxy-2-piperidinones 6 and their tautomeric ring-opened keto amides 7 is described. The reduction with L-Selectride at -20 degrees C to room temperature afforded the products 10 in excellent yields and moderate to high syn-diastereoselectivities.

Quasimolecular emission near the Xe(5p 56s 1,3 P 1 - 5p 6 1 S 0) and Kr (4p 55s 1,3 P 1 - 4p 6 1 S 0) resonance lines induced by collisions with He atoms

Science.gov (United States)

Alekseeva, O. S.; Devdariani, A. Z.; Grigorian, G. M.; Lednev, M. G.; Zagrebin, A. L.

2017-02-01

This study is devoted to the theoretical investigation of the quasimolecular emission of Xe*-He and Kr*-He collision pairs near the Xe (5p 56s 1,3 P 1 - 5p 6 1 S 0) and Kr (4p 55s 1,3 P 1 - 4p 6 1 S 0) resonance atomic lines. The potential curves of the quasimolecules Xe(5p 56s) + He and Kr(4p 55s) + He have been obtained with the use of the effective Hamiltonian and pseudopotential methods. Based on these potential curves the processes of quasimolecular emission of Xe*+He and Kr*+He mixtures have been considered and the spectral distributions I(ħΔω) of photons emitted have been obtained in the framework of quasistatic approximation.

Proceedings – Mathematical Sciences | Indian Academy of Sciences

Indian Academy of Sciences (India)

Author Affiliations. Radu Ioan Boţ1 Anca Dumitru2 Gert Wanka1. Faculty of Mathematics, Chemnitz University of Technology, D-09107 Chemnitz, Germany; Faculty of Mathematics and Computer Science, Babes¸-Bolyai University, Str. Kog˜alniceanu nr. 1, 400084 Cluj-Napoca, Romania ...

Introduction

Directory of Open Access Journals (Sweden)

Beth J. CIESIELSKI

2000-06-01

Full Text Available Students in the Faculty of Political Science, Department of Public Administration at Babes – Bolyai University, Cluj–Napoca, Romania wrote the following Non Governmental Organization (NGO case studies. “NGO Management” was the first course offered NGO management by the university.

Neumann and Neumann-Rosochatius integrable systems from membranes on AdS4 x S7

International Nuclear Information System (INIS)

Bozhilov, Plamen

2007-01-01

It is known that large class of classical string solutions in the type IIB AdS 5 x S 5 background is related to the Neumann and Neumann-Rosochatius integrable systems, including spiky strings and giant magnons. It is also interesting if these integrable systems can be associated with some membrane configurations in M-theory. We show here that this is indeed the case by presenting explicitly several types of membrane embedding in AdS 4 x S 7 with the searched properties

A major electronics upgrade for the H.E.S.S. Cherenkov telescopes 1-4

CERN Document Server

Giavitto, G; Balzer, A.; Berge, D.; Brun, F.; Chaminade, T.; Delagnes, E.; Fontaine, G.; Füßling, M.; Giebels, B.; Glicenstein, J.F.; Gräber, T.; Hinton, J.A.; Jahnke, A.; Klepser, S.; Kossatz, M.; Kretzschmann, A.; Lefranc, V.; Leich, H.; Lüdecke, H.; Manigot, P.; Marandon, V.; Moulin, E.; de, M.; Nayman, P.; Penno, M.; Ross, D.; Salek, D.; Schade, M.; Schwab, T.; Simoni, R.; Stegmann, C.; Thornhill, J.; Toussenel, F.

2015-01-01

The High Energy Stereoscopic System (H.E.S.S.) is an array of imaging atmospheric Cherenkov telescopes (IACTs) located in the Khomas Highland in Namibia. It consists of four 12-m telescopes (CT1-4), which started operations in 2003, and a 28-m diameter one (CT5), which was brought online in 2012. It is the only IACT system featuring telescopes of different sizes, which provides sensitivity for gamma rays across a very wide energy range, from ~30 GeV up to ~100 TeV. Since the camera electronics of CT1-4 are much older than the one of CT5, an upgrade is being carried out; first deployment was in 2015, full operation is planned for 2016. The goals of this upgrade are threefold: reducing the dead time of the cameras, improving the overall performance of the array and reducing the system failure rate related to aging. Upon completion, the upgrade will assure the continuous operation of H.E.S.S. at its full sensitivity until and possibly beyond the advent of CTA. In the design of the new components, several CTA con...

The crystal structure of kudriavite, (Cd,Pb)Bi2S4

DEFF Research Database (Denmark)

Balic Zunic, Tonci; Makovicky, Emil

2007-01-01

The crystal structure of kudriavite, (Cd,Pb)Bi2S4, a new mineral species, was solved from single-crystal X-ray-diffraction data and refi ned to R = 4.9% (4.3% for a model with split mixed-cation sites). Lattice parameters are a 13.095(1), b 4.0032(3), c 14.711(1) Å, 115.59(1)°, V 695.6(1) Å3....... The structure is equivalent to that of synthetic CdBi2S4, space group C2/m, Z = 4, and represents a pavonite homologue, N = 3. It is built of three-octahedron-thick columns of (311)PbS-like slabs combined by "unitcell twinning" in a quasi-mirror-glide succession. The slabs, which are intrinsically of the same...... topology, differ in the coordination state of bordering cations because of the relative positions of the adjacent layers. In the slabs of type I (the "non-accreting" slab common to all pavonite homologues), the central columns of octahedra are fl anked by half-octahedral (square-pyramidal) coordinations...

Assembly of the 30S subunit from Escherichia coli ribosomes occurs via two assembly domains which are initiated by S4 and S7

International Nuclear Information System (INIS)

Nowotny, V.; Nierhaus, K.H.

1988-01-01

A protein which initiates assembly of ribosomes is defined as a protein which binds to the respective rRNA without cooperativity (i.e., without the help of other proteins) during the onset of assembly and is essential for the formation of active ribosomal subunits. The number of proteins binding without cooperativity was determined by monitoring the reconstitution output of active particles at various inputs of 16S rRNA, in the present of constant amounts of 30S-derived proteins (TP30): This showed that only two of the proteins of the 30S subunit are assembly-initiator proteins. These two proteins are still present on a LiCl core particle comprising 16S rRNA and 12 proteins (including minor proteins). The 12 proteins were isolated, and a series of reconstitution experiments at various levels of rRNA excess demonstrated that S4 and S7 are the initiator proteins. Pulse-chase experiments performed during the early assembly with 14 C- and 3 H-labeled TP30 and the determination of the 14 C/ 3 H ratio of the individual proteins within the assembled particles revealed a bilobal structure of the 30S assembly: A group of six proteins headed by S4 (namely, S4, S20, S16, S15, S6, and S18) resisted the chasing most efficiently (S4 assembly domain). None of the proteins depending on S7 during assembly were found in this group but rather in a second group with intermediate chasing stability [S7 assembly domain; consisting of S7, S9, (S8), S19, and S3]. A number of proteins could be fully chased during the early assembly and therefore represent late assembly proteins (S10, S5, S13, S2, S21, S1). These findings fit well with the 30S assembly map. These data, together with the assembly map, imply that S8 and S5 play an important role in the interconnection of the two assembly domains

The role of extended Fe4S4 cluster ligands in mediating sulfite reductase hemoprotein activity.

Science.gov (United States)

Cepeda, Marisa R; McGarry, Lauren; Pennington, Joseph M; Krzystek, J; Elizabeth Stroupe, M

2018-05-28

The siroheme-containing subunit from the multimeric hemoflavoprotein NADPH-dependent sulfite reductase (SiR/SiRHP) catalyzes the six electron-reduction of SO 3 2- to S 2- . Siroheme is an iron-containing isobacteriochlorin that is found in sulfite and homologous siroheme-containing nitrite reductases. Siroheme does not work alone but is covalently coupled to a Fe 4 S 4 cluster through one of the cluster's ligands. One long-standing hypothesis predicted from this observation is that the environment of one iron-containing cofactor influences the properties of the other. We tested this hypothesis by identifying three amino acids (F437, M444, and T477) that interact with the Fe 4 S 4 cluster and probing the effect of altering them to alanine on the function and structure of the resulting enzymes by use of activity assays, X-ray crystallographic analysis, and EPR spectroscopy. We showed that F437 and M444 gate access for electron transfer to the siroheme-cluster assembly and the direct hydrogen bond between T477 and one of the cluster sulfides is important for determining the geometry of the siroheme active site. Copyright © 2018. Published by Elsevier B.V.

A General and Simple Diastereoselective Reduction by L-Selectride: Efficient Synthesis of Protected (4S,5S-Dihydroxy Amides

Directory of Open Access Journals (Sweden)

Bo Yin

2010-04-01

Full Text Available A general approach to (4S,5S-4-benzyloxy-5-hydroxy-N-(4-methoxybenzyl amides 10 based on a diastereoselective reduction of (5S,6RS-6-alkyl-5-benzyloxy-6-hydroxy-2-piperidinones 6 and their tautomeric ring-opened keto amides 7 is described. The reduction with L-Selectride at -20 °C to room temperature afforded the products 10 in excellent yields and moderate to high syn-diastereoselectivities.

Nitrosylation of Nitric-Oxide-Sensing Regulatory Proteins Containing [4Fe-4S] Clusters Gives Rise to Multiple Iron-Nitrosyl Complexes

Energy Technology Data Exchange (ETDEWEB)

Serrano, Pauline N. [Department of Chemistry, University of California, Davis CA 95616 USA; Wang, Hongxin [Department of Chemistry, University of California, Davis CA 95616 USA; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley CA 94720 USA; Crack, Jason C. [Centre for Molecular and Structural Biochemistry, School of Chemistry, University of East Anglia, Norwich Research Park Norwich NR4 7TJ UK; Prior, Christopher [Centre for Molecular and Structural Biochemistry, School of Chemistry, University of East Anglia, Norwich Research Park Norwich NR4 7TJ UK; Hutchings, Matthew I. [School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ UK; Thomson, Andrew J. [Centre for Molecular and Structural Biochemistry, School of Chemistry, University of East Anglia, Norwich Research Park Norwich NR4 7TJ UK; Kamali, Saeed [University of Tennessee Space Institute, Tullahome TN 37388-9700 USA; Yoda, Yoshitaka [Research and Utilization Division, SPring-8/JASRI, 1-1-1 Kouto, Sayo Hyogo 679-5198 Japan; Zhao, Jiyong [Advanced Photon Source, Argonne National Laboratory, Argonne IL 60439 USA; Hu, Michael Y. [Advanced Photon Source, Argonne National Laboratory, Argonne IL 60439 USA; Alp, Ercan E. [Advanced Photon Source, Argonne National Laboratory, Argonne IL 60439 USA; Oganesyan, Vasily S. [Centre for Molecular and Structural Biochemistry, School of Chemistry, University of East Anglia, Norwich Research Park Norwich NR4 7TJ UK; Le Brun, Nick E. [Centre for Molecular and Structural Biochemistry, School of Chemistry, University of East Anglia, Norwich Research Park Norwich NR4 7TJ UK; Cramer, Stephen P. [Department of Chemistry, University of California, Davis CA 95616 USA; Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley CA 94720 USA

2016-10-25

The reaction of protein-bound iron–sulfur (Fe-S) clusters with nitric oxide (NO) plays key roles in NO-mediated toxicity and signaling. Elucidation of the mechanism of the reaction of NO with DNA regulatory proteins that contain Fe-S clusters has been hampered by a lack of information about the nature of the iron-nitrosyl products formed. Herein, we report nuclear resonance vibrational spectroscopy (NRVS) and density functional theory (DFT) calculations that identify NO reaction products in WhiD and NsrR, regulatory proteins that use a [4Fe-4S] cluster to sense NO. This work reveals that nitrosylation yields multiple products structurally related to Roussin's Red Ester (RRE, [Fe₂(NO)₄(Cys)₂]) and Roussin's Black Salt (RBS, [Fe₄(NO)₇S₃]. In the latter case, the absence of ³²S/³⁴S shifts in the Fe-S region of the NRVS spectra suggest that a new species, Roussin's Black Ester (RBE), may be formed, in which one or more of the sulfide ligands is replaced by Cys thiolates.

Effect of MoS2 on hydrogenation storage properties of LiBH4

International Nuclear Information System (INIS)

Liang, Dan; Han, Shumin; Wang, Jiasheng; Zhang, Wei; Zhao, Xin; Zhao, Ziyang

2014-01-01

The hydrogen storage properties of LiBH 4 ball milled with 20 wt% MoS 2 have been investigated. It shows that the LiBH 4 doped with MoS 2 exhibits favorable hydrogenation and dehydrogenation properties in terms of decomposition temperature and hydriding/dehydriding reversibility. The sample with MoS 2 starts to release hydrogen at 230 °C and has a decrease of 80 °C in contrast with pristine LiBH 4 . Furthermore, for the second cycle, the LiBH 4 with MoS 2 maintains a reversible hydrogen storage capacity of about 8.0 wt% which is almost identical with the first cycle under 5 MPa at 550 °C. Analyzed by the XRD and the FTIR results, LiBH 4 can be regenerated after re-hydrogenation under a relatively mild condition by adding MoS 2 . The improvement of the hydrogenation and dehydrogenation properties mainly results from the formation of Li 2 S and MoB 2 during ball milling. -- Graphical abstract: Hydrogen absorption curves of LiBH 4 doped with MoS 2 for five cycles at 400 °C. Highlights: • The hydrogen absorption capacity is nearly the same for 5 cycles at 400 °C. • The sample with MoS 2 starts to release hydrogen at 230 °C. • The coexistence of MoB 2 and Li 2 S catalyzes the decomposition of LiBH 4

Preparation of NiS/ZnIn2S4 as a superior photocatalyst for hydrogen evolution under visible light irradiation

Directory of Open Access Journals (Sweden)

Liang Wei

2013-12-01

Full Text Available In this study, NiS/ZnIn2S4 nanocomposites were successfully prepared via a facile two-step hydrothermal process. The as-prepared samples were characterized by X-ray diffraction (XRD, X-ray photoelectron spectroscopy (XPS, transmission electron microscopy (TEM and high-resolution transmission electron microscopy (HRTEM. Their photocatalytic performance for hydrogen evolution under visible light irradiation was also investigated. It was found that the photocatalytic hydrogen evolution activity over hexagonal ZnIn2S4 can be significantly increased by loading NiS as a co-catalyst. The formation of a good junction between ZnIn2S4 and NiS via the two step hydrothermal processes is beneficial for the directional migration of the photo-excited electrons from ZnIn2S4 to NiS. The highest photocatalytic hydrogen evolution rate (104.7 μmol/h, which is even higher than that over Pt/ZnIn2S4 nanocomposite (77.8 μmol/h, was observed over an optimum NiS loading amount of 0.5 wt %. This work demonstrates a high potential of the developing of environmental friendly, cheap noble-metal-free co-catalyst for semiconductor-based photocatalytic hydrogen evolution.

Genetic selection and DNA sequences of 4.5S RNA homologs

DEFF Research Database (Denmark)

Brown, S; Thon, G; Tolentino, E

1989-01-01

A general strategy for cloning the functional homologs of an Escherichia coli gene was used to clone homologs of 4.5S RNA from other bacteria. The genes encoding these homologs were selected by their ability to complement a deletion of the gene for 4.5S RNA. DNA sequences of the regions encoding...

Digitalis en atriumfibrilleren anno 1985

NARCIS (Netherlands)

Meijler, F.L.; Tweel, I. van der

1985-01-01

In dit artikel worden enkele fundamentele aspecten van atriumfibrilleren en de rol van het atrioventriculaire geleidingssysteem daarbij besproken die ook van belang kunnen zijn voor de eerstelijnsgezondheidszorg, waarbij tevens aandacht wordt besteed aan de werking van digitalis.

(Ph4P)S6—A Compound Containing the Cyclic Radical Anion S6.−

NARCIS (Netherlands)

Neumuller, F.; Schmock, R.; Kirmse, A.; Voigt, A.; Diefenbach, A.; Bickelhaupt, F.M.; Dehnicke, K.

2000-01-01

Two long S−S bonds link the two S3 fragments in the cyclic radical anion S6.−. This forms as orange‐red crystals with PPh4+ as the counterion in the reaction of sulfane with (tetraphenylphosphonium) hydrogen diazide. The anion has a chair conformation with C2h symmetry (see picture).

S100A4, a link between metastasis and inflammation

DEFF Research Database (Denmark)

Ambartsumian, N.; Grigorian, M.

2016-01-01

Chronic inflammation is acknowledged to be a hallmark of neoplasia—both in cancer initiation and metastasis progression. Here we summarise data suggesting that S100A4 is а trigger of the cascade events that establish an inflammatory milieu and provide a potent flame for primary tumour growth......-communicable diseases (NCD), such as autoimmune diseases, fibrosis, and other disorders. Therefore, we suggest that S100A4 is a common pro-inflammatory factor involved in the pathogenesis of diverse NCD including cancer....

Emergence of a new S U (4 ) symmetry in the baryon spectrum

Science.gov (United States)

Denissenya, M.; Glozman, L. Ya.; Pak, M.

2015-10-01

Recently, a large degeneracy of J =1 mesons—that is, larger than the S U (2 )L×S U (2 )R×U (1 )A symmetry of the QCD Lagrangian—has been discovered upon truncation of the near-zero modes from the valence quark propagators. It has been found that this degeneracy represents the S U (4 ) group that includes the chiral rotations as well as the mixing of left- and right-handed quarks. This symmetry group turns out to be a symmetry of confinement in QCD. Consequently, one expects that the same symmetry should persist upon the near-zero mode removal in other hadron sectors as well. It has been shown that indeed the J =2 mesons follow the same symmetry pattern upon the low-lying mode elimination. Here we demonstrate the S U (4 ) symmetry of baryons once the near-zero modes are removed from the quark propagators. We also show a degeneracy of states belonging to different irreducible representations of S U (4 ). This implies a larger symmetry that includes S U (4 ) as a subgroup.

Strongly perturbed Rydberg series originating from KrII 4p45s ionic states

International Nuclear Information System (INIS)

Petrov, I.D.; Demekhin, Ph.V.; Lagutin, B.M.; Sukhorukov, V.L.; Kammer, S.; Mickat, S.; Schartner, K.-H.; Ehresmann, A.; Klumpp, S.; Werner, L.; Schmoranzer, H.

2005-01-01

Photoionization cross-sections for the 4p 4 ( 3 P) 5s 4 P 5/2,3/2,1/2 satellites and 4s, 4p main levels of Kr II in the exciting-photon energy range between 28.48 and 28.70-bar eV with extremely narrow bandwidth (1.7-bar meV at 28.55-bar eV) of the monochromatized synchrotron radiation were measured utilizing the photon-induced fluorescence spectroscopy. The observed resonances were assigned to the 4p 4 5s( 4 P 1/2 )n p and 4p 4 5s( 2 P 3/2 )n p Rydberg series on the basis of calculations performed with taking into account core relaxation and interaction between many resonances and many continua. The calculation shows that the resonance structure in the photoionization channels exists due to 4p 4 ( 1 D) 5s 2 D 5/2 6p 3/2 promoter state which also strongly perturbs the above Rydberg series.

The influence of pressure on the birefringence in semiconductor compounds ZnS, CuGaS2, and InPS4

International Nuclear Information System (INIS)

Lavrentyev, A.A.; Gabrelian, B.V.; Kulagin, B.B.; Nikiforov, I.Ya.; Sobolev, V.V.

2007-01-01

Using the modified method of augmented plane waves and the code WIEN2k the calculations of the electron band structure, densities of electron states, and imaginary part of dielectric response function were carried out for different polarization of the vector of electrical field ε xx and ε zz for the semiconductor compounds ZnS, CuGaS 2 , and InPS 4 . The calculations were performed both for undisturbed crystals and for distorted crystals due to the applied pressure. The compounds studied have the similar crystallographic structures: ZnS - sphalerite, CuGaS 2 - chalcopyrite, and InPS 4 - twice defective chalcopyrite. It is known, that in cubic ZnS there is no birefringence, whereas in CuGaS 2 and InPS 4 there is one. But CuGaS 2 has so called isotropic point (where ε xx =ε zz ) in the visible optical range, and InPS 4 has no such point. Our calculations of ε xx and ε zz have shown that in ZnS under the pressure the isotropic points arise, but in InPS 4 they do not exist. (copyright 2007 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

Influence of complexing agent (Na2EDTA on chemical bath deposited Cu4SnS4 thin films

Directory of Open Access Journals (Sweden)

Anuar Kassim

2010-08-01

Full Text Available The quality of thin film is influenced by the presence of complexing agents such as Na2EDTA. The Cu4SnS4 thin films were deposited onto indium tin oxide glass substrate by chemical bath deposition method. The structural, morphological and optical properties of the deposited films have been studied using X-ray diffraction, atomic force microscopy and UV-Vis spectrophotometer, respectively. The XRD data showed that the films have a polycrystalline and orthorhombic structure. It also indicated that the most intense peak at 2 θ = 30.2° which belongs to (221 plane of Cu4 SnS4. The film deposited with 0.05 M Na2 EDTA showed good uniformity, good surface coverage with bigger grains and produced higher absorbance value. The band gap energy varies with the variation of Na2EDTA concentration which ranging from 1.56-1.60 eV. Deposition at concentration of 0.05 M Na2EDTA proved to offer a reasonably good Cu4SnS4 thin film.

Role of DDC-4/sFRP-4, a secreted frizzled-related protein, at the onset of apoptosis in mammary involution.

Science.gov (United States)

Lacher, M D; Siegenthaler, A; Jäger, R; Yan, Xi; Hett, S; Xuan, L; Saurer, S; Lareu, R R; Dharmarajan, A M; Friis, R

2003-05-01

Using differential display, we isolated DDC-4, a secreted frizzled-related protein (sFRP), which is induced in the physiological apoptosis of hormonally regulated, reproductive tissues such as mammary gland, prostate, corpus luteum and uterus. The role of this gene in apoptosis was studied in animals overexpressing ectopic DDC-4/sFRP-4. Transgenic mice bearing the DDC-4/sFRP-4 cDNA under the control of the MMTV-LTR promoter showed lactational insufficiency and many apoptotic cells in the alveoli between day 19 of pregnancy and day 4 of lactation as demonstrated by TUNEL reaction and the presence of activated caspase-3. We performed a PKB/Akt kinase assay and studied several of its substrates using phosphorylation-specific antibodies to show reduced phosphorylation in PKB/Akt itself, as well as in glycogen synthetase kinase-3beta (GSK-3beta), BAD, and Forkhead. Taken together, our results show a role for DDC-4/sFRP-4 in abrogating an epithelial cell survival pathway at the onset of mammary gland involution.

China’s regional CH_4 emissions: Characteristics, interregional transfer and mitigation policies

International Nuclear Information System (INIS)

Zhang, Bo; Yang, T.R.; Chen, B.; Sun, X.D.

2016-01-01

Highlights: • China’s CH_4 emissions have significant contributions to global climate change. • The total CH_4 emissions in 2010 amount to 44.3 Tg, half from energy activities. • Half of the national total direct emissions are embodied in interregional trade. • 2/3 of the embodied emission transfers via domestic trade are energy-related. • A national comprehensive action plan to reduce CH_4 emissions should be designed. - Abstract: Methane (CH_4), the second largest greenhouse gas emitted in China, hasn’t been given enough attention in the country’s policies and actions for addressing climate change. This paper aims to perform a bottom-up estimation and multi-regional input–output analysis for China’s anthropogenic CH_4 emissions from both production-based and consumption-based insights. As the world’s largest CH_4 emitter, China’s total anthropogenic CH_4 emissions in 2010 are estimated at 44.3 Tg and correspond to 1507.9 Mt CO_2-eq by the lower global warming potential factor of 34. Energy activities as the largest contributor hold about half of the national total emissions, mainly from coal mining. Inherent economic driving factors covering consumption, investment and international exports play an important role in determining regional CH_4 emission inventories. Interregional transfers of embodied emissions via domestic trade are equivalent to half of the national total emissions from domestic production, of which two thirds are energy-related embodied emissions. Most central and western regions as net interregional CH_4 exporters such as Shanxi and Inner Mongolia have higher direct emissions, while the eastern coastal regions as net interregional importers such as Guangdong and Jiangsu always have larger embodied emissions. Since China’s CH_4 emissions have significant contributions to global climate change, a national comprehensive action plan to reduce CH_4 emissions should be designed by considering supply-side and demand

Development of 4S and related technologies. (3) Statistical evaluation of safety performance of 4S on ULOF event

International Nuclear Information System (INIS)

Ishii, Kyoko; Matsumiya, Hisato; Horie, Hideki; Miyagi, Kazumi

2009-01-01

The purpose of this work is to evaluate quantitatively and statistically the safety performance of Super-Safe, Small, and Simple reactor (4S) by analyzing with ARGO code, a plant dynamics code for a sodium-cooled fast reactor. In this evaluation, an Anticipated Transient Without Scram (ATWS) is assumed, and an Unprotected Loss of Flow (ULOF) event is selected as a typical ATWS case. After a metric concerned with safety design is defined as performance factor a Phenomena Identification Ranking Table (PIRT) is produced in order to select the plausible phenomena that affect the metric. Then a sensitivity analysis is performed for the parameters related to the selected plausible phenomena. Finally the metric is evaluated with statistical methods whether it satisfies the given safety acceptance criteria. The result is as follows: The Cumulative Damage Fraction (CDF) for the cladding is defined as a metric, and the statistical estimation of the one-sided upper tolerance limit of 95 percent probability at a 95 percent confidence level in CDF is within the safety acceptance criterion; CDF < 0.1. The result shows that the 4S safety performance is acceptable in the ULOF event. (author)

S100A4 and BMP-2 Co-Dependently Induce Vascular Smooth Muscle Cell Migration via pERK and Chloride Intracellular Channel 4 (CLIC4)

Science.gov (United States)

Spiekerkoetter, Edda; Guignabert, Christophe; de Jesus Perez, Vinicio; Alastalo, Tero-Pekka; Powers, Janine M; Wang, Lingli; Lawrie, Allan; Ambartsumian, Noona; Schmidt, Ann-Marie; Berryman, Mark; Ashley, Richard H; Rabinovitch, Marlene

2009-01-01

Rationale S100A4/Mts1 is implicated in motility of human pulmonary artery smooth muscle cells (hPASMC), through an interaction with the receptor for advanced glycation end products (RAGE). Objective We hypothesized that S100A4/Mts1-mediated hPASMC motility might be enhanced by loss of function of bone morphogenetic protein (BMP) receptor (R) II, observed in pulmonary arterial hypertension (PAH). Methods and Results Both S100A4/Mts1 (500ng/ml) and BMP-2 (10ng/ml) induce migration of hPASMCS in a novel co-dependent manner, in that the response to either ligand is lost with anti-RAGE or BMPRII siRNA. Phosphorylation of ERK is induced by both ligands and is required for motility by inducing MMP2 activity, but phosphoERK1/2 is blocked by anti-RAGE and not by BMPRII siRNA. In contrast, BMPRII siRNA, but not anti-RAGE, reduces expression of intracellular chloride channel 4 (CLIC4), a scaffolding molecule necessary for motility in response to S100A4/Mts1 or BMP-2. Reduced CLIC4 expression does not interfere with S100A4/Mts1 internalization or its interaction with myosin heavy chain IIA (MHCIIA), but does alter alignment of MHCIIA and actin filaments creating the appearance of vacuoles. This abnormality is associated with reduced peripheral distribution and/or delayed activation of RhoA and Rac1, small GTPases required for retraction and extension of lamellipodiae in motile cells. Conclusions Our studies demonstrate how a single ligand (BMP-2 or S100A4/Mts1) can recruit multiple cell surface receptors to relay signals that coordinate events culminating in a functional response, i.e., cell motility. We speculate that this carefully controlled process limits signals from multiple ligands, but could be subverted in disease. PMID:19713532

On the possibility of developing quasi-CW high-power high-pressure laser on 4p-4s transition of ArI with electron beam—optical pumping: quenching of 4s (3P2) lower laser level

Science.gov (United States)

Ionin, A. A.; Kholin, I. V.; L'dov, A. Yu; Seleznev, L. V.; Ustinovskii, N. N.; Zayarnyi, D. A.

2017-12-01

A new electron beam-optical procedure is proposed for quasi-cw pumping of high-pressure large-volume He-Ar laser on the 4p[1/2]1-4s[3/2]20 argon atom transition at the wavelength of 912.5 nm. It consists of creation and maintenance of a necessary density of the 4s[3/2]20 metastable state in the gain medium by a fast electron beam and subsequent optical pumping of the upper laser level via the classical three-level scheme using a laser diode. Absorption probing is used to study collisional quenching of Ar* metastable in electron-beam-excited high-pressure He-Ar mixtures with a low content of argon. The rate constants for plasma-chemical reactions Ar*  +  He  +  Ar  >  Ar2*   +  He (3.6  ±  0.4)  ×  10-33 cm6 s-1, Ar*  +  2He  >  HeAr*  +  He (4.4  ±  0.9)  ×  10-36 cm6 s-1 and Ar*  +  He  >  Products  +  He (2.4  ±  0.3)  ×  10-15 cm3 s-1 were for the first time measured.

One-electron capture into Li-like autoionising N4+ (1s2ln'l') configurations by metastable N5+ (1s2s3S) multicharged ions in collisions with He and H2, observed by electron spectrometry at 3.4 keV amu-1

International Nuclear Information System (INIS)

Bordenave-Montesquieu, A.; Benoit-Cattin, P.; Gleizes, A.

1985-01-01

One-electron capture into N 4+ (1s2ln'l') configurations, with n'=2 to 4, has been observed by electron spectrometry when a N 5+ (1s2s 3 S) multicharged ion beam encounters an He or H 2 target, at low collision velocity (upsilon=0.37 au) within single-collision conditions. Contributions of other 1s2l metastable states and of the 1s 2 ground state may be disregarded. A small indication of two-electron capture by 1s2s 3 S ions into (1s2s 3 S)3l3l' configurations is also seen. (author)

Strongly perturbed Rydberg series originating from Kr II 4p45s ionic states

International Nuclear Information System (INIS)

Petrov, I.D.; Demekhin, P.V.; Lagutin, B.M.; Sukhorukov, V.L.; Kammer, S.; Mickat, S.; Schartner, K.-H.; Ehresmann, A.; Klumpp, S.; Werner, L.; Schmoranzer, H.

2004-01-01

Full text:Dispersed fluorescence excitation spectra for KrII fluorescence transitions to the 4p 4 5s 4 P 3/2 , 5/2 states were observed after excitation out of the KrI ground state with photons of energies between 28.4 eV and 28.7 eV and very narrow exciting-photon bandwidth of 1.7 meV. With this energy resolution it was possible to observe Rydberg series of doubly excited atomic states. The observed series were assigned to the states 4p 4 5s( 4 P 1/2 )np and 4p 4 5s( 2 P 3/2 )np ,based on calculations performed within theory taking into account interaction between many resonances and many continua. Calculated and measured cross sections are compared for the 4p - level (upper panel, ion yield) and for the 4p 4 5s 4 P 5/2 level (lower panel). An analysis of the computed photoionization (PI) cross sections shows that high - n members of Rydberg series are strongly perturbed by interaction with low - n ones of other series. In particular, the series shown are well pronounced because they borrow intensity from the low - n 4p 4 5s( 2 D 5/2 )6p 3/2 doublyexcited state. The above Rydberg series are predicted to be observable in photoelectron experiments, too. FIG. 1 shows, e.g., that members of the 4p 4 5s( 2 P 3/2 )np series starting from n 14 could also be observed in the 4p 4 5s 4P 1/2 observer channel at low photoelectron energies

Different proportions of C/KCu7S4 hybrid structure for high-performance supercapacitors

Science.gov (United States)

Dai, Shuge; Xi, Yi; Hu, Chenguo; Yue, Xule; Cheng, Lu; Wang, Guo

2014-10-01

KCu7S4 has the channel structure and minor resistance. Its double larger channels ensure that the ions can well exchange with other's, at the same time, can shorten the ionic diffusion path and improve the ionic and electronic transport. So KCu7S4 shows good electrochemical property. The paper reports a novel and high performance supercapacitor based on hybrid carbon particles and KCu7S4 (C/KCu7S4) electrode. For the hybrid structure with different proportions of C and KCu7S4, the C/KCu7S4 (1:10) hybrid supercapacitor shows preferable electrochemical performance and large specific capacitance (469 mF cm-2) at high charge-discharge rate (2 mA), still retaining ∼95% of the capacitance over 5000 cycles by charge-discharge process at a fixed current of 10 mA. Three supercapacitor units in series can light 50 light-emitting diodes (LEDs) for 2.5 min, 10 LEDs for 4 min, one LED for 5.5 min. The much-increased capacity, rate capability, and cycling stability may be attributed to the superionic conductive KCu7S4 nanowires and C/KCu7S4 hybrid structure, which improve ionic and electronic transport, enhance the kinetics of redox reactions through the electrode system.

Toets Altmark-criteria: veerverbinding Boven Hardinxveld - Werkendam - Gorinchem - Sleeuwijk

NARCIS (Netherlands)

Compernolle, P.; van der Voort, A.J.M.; Smits, T.

2013-01-01

De gemeente Gorinchem heeft de veerverbinding Boven Hardinxveld - Werkendam -Gorinchem - Sleeuwijk aangemerkt als Dienst van Algemeen Economisch Belang (DAEB). De interne veerdienst van Gorinchem is vervolgens aangewezen als uitvoerder voor deze veerverbinding. SEO Economisch Onderzoek werd door de

Hemoglobine A1c. Ontwikkeling van een bepalingsmethode en enige klinische toepassingen

NARCIS (Netherlands)

Miedema, Kornelis

1981-01-01

In dit proefschrift wordt een kolomchromatografische bepalingsmethode van het HbA1c beschreven. Het belang van deze bepaling voor de controle van patiënten met diabetes mellites wordt in een aantal klinische studies nagegaan. ... Zie: Samenvatting

New insights into the structure, chemistry, and properties of Cu.sub.4./sub.SnS.sub.4./sub.

Czech Academy of Sciences Publication Activity Database

Choudhury, A.; Mohapatra, S.; Asl, H.Y.; Lee, S.H.; Hor, Y.S.; Medvedeva, J.E.; McClane, D.L.; Hilmas, G.E.; McGuire, M.A.; May, A.H.; Wang, H.; Dash, S.; Welton, A.; Boolchand, P.; Devlin, K.P.; Aitken, J.; Herbst-Irmer, R.; Petříček, Václav

2017-01-01

Roč. 253, Sep (2017), s. 192-201 ISSN 0022-4596 Institutional support: RVO:68378271 Keywords : Cu 4 SnS 4 * phase transition * crystal structure * electronic properties * thermoelectrics * band structure * 119-Sn Mössbauer Subject RIV: BM - Solid Matter Physics ; Magnetism OBOR OECD: Condensed matter physics (including formerly solid state physics, supercond.) Impact factor: 2.299, year: 2016

Inkjet?Printed Cu2ZnSn(S, Se)4 Solar Cells

OpenAIRE

Lin, Xianzhong; Kavalakkatt, Jaison; Lux?Steiner, Martha Ch.; Ennaoui, Ahmed

2015-01-01

Cu2ZnSn(S, Se)4?based solar cells with total area (0.5 cm2) power conversion efficiency of 6.4% are demonstrated from thin film absorbers processed by inkjet printing technology of Cu?Zn?Sn?S precursor ink followed by selenization. The device performance is limited by the low fill factor, which is due to the high series resistance.

Inkjet-Printed Cu2ZnSn(S, Se)4 Solar Cells.

Science.gov (United States)

Lin, Xianzhong; Kavalakkatt, Jaison; Lux-Steiner, Martha Ch; Ennaoui, Ahmed

2015-06-01

Cu 2 ZnSn(S, Se) 4 -based solar cells with total area (0.5 cm 2 ) power conversion efficiency of 6.4% are demonstrated from thin film absorbers processed by inkjet printing technology of Cu-Zn-Sn-S precursor ink followed by selenization. The device performance is limited by the low fill factor, which is due to the high series resistance.

Cluster-spin dynamics in a GaMo{sub 4}S{sub 8}-type compound: {sup 27}Al nuclear magnetic resonance study of AlMo{sub 4}S{sub 8}

Energy Technology Data Exchange (ETDEWEB)

Ikeno, R; Nakamura, H; Kohara, T [Graduate School of Material Science, University of Hyogo, Kamigori, Ako-gun, Hyogo 678-1297 (Japan)

2007-01-31

The cluster-spin dynamics of the tetrahedral Mo{sub 4} cluster, involved in AlMo{sub 4}S{sub 8} with a cubic GaMo{sub 4}S{sub 8} type structure, was investigated by NMR of the nonmagnetic {sup 27}Al site located outside the cluster. The nuclear spin-lattice relaxation is described well by the conventional local moment model assuming the presence of S=1/2 at each cluster, indicating that each Mo{sub 4} cluster behaves like a local spin with rigid magnitude. This behaviour is in contrast to the in-cluster relaxation, which reflects the spin-density fluctuations inside the cluster as a small unit of metal.

Some Strategies for Strengthening Research and Teaching in the Era of the Bologna Process

Directory of Open Access Journals (Sweden)

Bernadine VAN GRAMBERG

2006-10-01

Full Text Available Universities across the world are undergoing rapid, and often significant, change to compete in an increasingly global environment. The Bologna process of higher education reforms has had its impact not only across Europe but globally given the pressure on universities to compete and to provide students with transferable qualifications in the quest for borderless education. As part of the process universities have been encouraged to differentiate themselves, particularly in terms of being research focused or teaching focus. As a result, many universities are putting in place strategies to boost their research output. With a view to contributing to the discussions by the International Advisory Board of the Department of Public Administration at Babes- Bolyai University, this paper overviews some of the strategies put in place by Australian Universities in order to improve the research output of their academic staff and provides some university marketing based suggestions for Babes-Bolyai University.

Chiral Recognition in Molecular and Macromolecular Pairs of(S)- and (R)- 1-Cyano-2-Methylpropyl 4’((4-(8-Vinyloxyoctyloxy)Benzoyl) Biphenyl-4-Carboxylate Enantiomers

Science.gov (United States)

1994-06-30

above please provide a graphical abstract of the paper ar, return it to the Editorial Office as soon as possible. 4oeg0 o F-99S or TS A& I DTI•’ I J. u1...TCLSICAON 2.LIMITATION OF ABSTRAC •F oFPORT OF THIS PAGE OF ABSTRACT . unclass ified Graphical Abstracts for Perkin Txans. 1 Example TITLE GRAPHICAL ... ABSTRACT AUTHORS’ N AMES Template (S)-II Chiral recognition in molecular and . -- macromolecular pairs of (S)- and -- (R)-i-cyano-2-methyipropyl 4’-{[4

S4S8-RPA phosphorylation as an indicator of cancer progression in oral squamous cell carcinomas.

Science.gov (United States)

Rector, Jeff; Kapil, Sasha; Treude, Kelly J; Kumm, Phyllis; Glanzer, Jason G; Byrne, Brendan M; Liu, Shengqin; Smith, Lynette M; DiMaio, Dominick J; Giannini, Peter; Smith, Russell B; Oakley, Greg G

2017-02-07

Oral cancers are easily accessible compared to many other cancers. Nevertheless, oral cancer is often diagnosed late, resulting in a poor prognosis. Most oral cancers are squamous cell carcinomas that predominantly develop from cell hyperplasias and dysplasias. DNA damage is induced in these tissues directly or indirectly in response to oncogene-induced deregulation of cellular proliferation. Consequently, a DNA Damage response (DDR) and a cell cycle checkpoint is activated. As dysplasia transitions to cancer, proteins involved in DNA damage and checkpoint signaling are mutated or silenced decreasing cell death while increasing genomic instability and allowing continued tumor progression. Hyperphosphorylation of Replication Protein A (RPA), including phosphorylation of Ser4 and Ser8 of RPA2, is a well-known indicator of DNA damage and checkpoint activation. In this study, we utilize S4S8-RPA phosphorylation as a marker for cancer development and progression in oral squamous cell carcinomas (OSCC). S4S8-RPA phosphorylation was observed to be low in normal cells, high in dysplasias, moderate in early grade tumors, and low in late stage tumors, essentially supporting the model of the DDR as an early barrier to tumorigenesis in certain types of cancers. In contrast, overall RPA expression was not correlative to DDR activation or tumor progression. Utilizing S4S8-RPA phosphorylation to indicate competent DDR activation in the future may have clinical significance in OSCC treatment decisions, by predicting the susceptibility of cancer cells to first-line platinum-based therapies for locally advanced, metastatic and recurrent OSCC.

Consument en cybersecurity : Een agenda voor Europese harmonisatie van zorgplichten

NARCIS (Netherlands)

Verbruggen, Paul; Wolters, P.T.J.

Cybersecurity – de beschikbaarheid, integriteit en vertrouwelijkheid van ICT-toepassingen – is van groot belang voor onze maatschappij. In deze bijdrage wordt onderzocht of en in hoeverre Europese harmonisatie van civielrechtelijke zorgplichten voor cybersecurity van ICT-toepassingen aangeboden aan

Hoge gebouwen van lokaal meer wind dan de norm

NARCIS (Netherlands)

Geurts, C.P.W.; Bentum, C.A. van

2007-01-01

De onderzoeksraad voor Veiligheid publiceerde in november 2006 het rapport 'Veiligheidsproblemen met gevelbekleding' van grote gebouwen. In een van de onderzochte projecten kwam het belang van windtunnelonderzoek naar voren. De windbelasting op gevelsystemen blijkt namelijk niet voor alle gevallen

Lange termijneffecten van jeugdparticipatie : Persistente effecten van deelname aan jeugdverenigingen in Nederland en de Verenigde Staten

NARCIS (Netherlands)

Bekkers, René; Hooghe, Marc; Stolle, Dietlind

2004-01-01

Gelet op het belang van primaire socialisatieprocessen, kan men van de verwachting uitgaan dat participatie in jeugdverenigingen persistente effecten zal hebben op latere gedrags- en attitudinale actoren. Deze effecten kunnen zowel verklaard worden vanuit een sociale integratie- (interiorisatie van

The prohibition order according to paragraph 5 S. 4 EnWG; Die Untersagungsverfuegung nach paragraph 5 S. 4 EnWG

Energy Technology Data Exchange (ETDEWEB)

Rauch, Karsten [WSW Netz GmbH, Wuppertal (Germany)

2011-02-10

The introduction of prosecutorial investigation on suspicion of delaying the insolvency proceedings published in the autumn 2010 results to a general question of whether and to what extent a concomitant intervention of the regulatory authorities is indicated. Central to this are the basis for authorization given in paragraph 5 S. 4 Energy Economy Law and the related prohibition authority.

{μ-2-[4-(1,3-Benzothiazol-2-ylphenyl]-2-azapropane-1,3-dithiolato-κ4S,S′:S,S′}bis[tricarbonyliron(I

Directory of Open Access Journals (Sweden)

Da-yong Jiang

2012-03-01

Full Text Available The title compound, [Fe2(C15H12N2S3(CO6], was prepared as an azadithiolatodiiron model for the active site of [FeFe]-hydrogenase. The Fe2S2 core adopts a butterfly shape, with each metal having a pseudo square-pyramidal geometry. The N-substituted azadithiolate is μ2-κ4S,S′:S,S′-coordinated to the Fe(CO3 moieties to form two fused six-membered rings with different conformations. The sum of the C—N—C angles around the N atom [356.85 (15°] indicates a flattening of the trigonal–pyramidal geometry about the N atom and an increase in the degree of sp2-hybridization.

Fast 4D cone-beam CT from 60 s acquisitions

Directory of Open Access Journals (Sweden)

David C. Hansen

2018-01-01

Full Text Available Background & purpose: Four dimensional Cone beam CT (CBCT has many potential benefits for radiotherapy but suffers from poor image quality, long acquisition times, and/or long reconstruction times. In this work we present a fast iterative reconstruction algorithm for 4D reconstruction of fast acquisition cone beam CT, as well as a new method for temporal regularization and compare to state of the art methods for 4D CBCT. Materials & methods: Regularization parameters for the iterative algorithms were found automatically via computer optimization on 60 s acquisitions using the XCAT phantom. Nineteen lung cancer patients were scanned with 60 s arcs using the onboard image on a Varian trilogy linear accelerator. Images were reconstructed using an accelerated ordered subset algorithm. A frequency based temporal regularization algorithm was developed and compared to the McKinnon-Bates algorithm, 4D total variation and prior images compressed sensing (PICCS. Results: All reconstructions were completed in 60 s or less. The proposed method provided a structural similarity of 0.915, compared with 0.786 for the classic McKinnon-bates method. For the patient study, it provided fewer image artefacts than PICCS, and better spatial resolution than 4D TV. Conclusion: Four dimensional iterative CBCT reconstruction was done in less than 60 s, demonstrating the clinical feasibility. The frequency based method outperformed 4D total variation and PICCS on the simulated data, and for patients allowed for tumor location based on 60 s acquisitions, even for slowly breathing patients. It should thus be suitable for routine clinical use.

The collision cross sections for excitation energy transfer in Rb*(5P3/2)+K(4S1/2)→Rb(5S1/2)+K*(4PJ) processes

International Nuclear Information System (INIS)

Horvatic, V.; Vadla, C.; Movre, M.

1993-01-01

The collisional excitation transfer for the processes Rb * (5P 3/2 ) + K(4S 1/2 ) → Rb(5S 1/2 ) + K * (4P J ), J = 1/2, 3/2, was investigated using two-photon laser excitation techniques with a thermionic heat-pipe diode as a detector. The population densities of the K 4P J levels induced by collisions with excited Rb atoms as well as those produced by direct laser excitation of the potassium atoms were probed through the measurement of the thermionic signals generated due to the ionization of the potassium atoms emerging from the K(4P J ) → K(7S 1/2 ) excitation channel. (orig./WL)

The metastasis-promoting S100A4 protein confers neuroprotection in brain injury

DEFF Research Database (Denmark)

Dmytriyeva, Oksana; Pankratova, Stanislava; Owczarek, Sylwia

2012-01-01

and downregulating the neuroprotective protein metallothionein I+II. We identify two neurotrophic motifs in S100A4 and show that these motifs are neuroprotective in animal models of brain trauma. Finally, we find that S100A4 rescues neurons via the Janus kinase/STAT pathway and, partially, the interleukin-10......Identification of novel pro-survival factors in the brain is paramount for developing neuroprotective therapies. The multifunctional S100 family proteins have important roles in many human diseases and are also upregulated by brain injury. However, S100 functions in the nervous system remain...... unclear. Here we show that the S100A4 protein, mostly studied in cancer, is overexpressed in the damaged human and rodent brain and released from stressed astrocytes. Genetic deletion of S100A4 exacerbates neuronal loss after brain trauma or excitotoxicity, increasing oxidative cell damage...

The transitions 4p-5s in Y VI, Zr VII, Nb VIII and Mo IX

International Nuclear Information System (INIS)

Chaghtai, M.S.Z.; Rahimullah, K.; Khatoon, S.

1976-01-01

With the help of the spectra recorded in the Physics Department of Lund University, Y VI, Zr VII, Nb VIII and Mo IX are freshly analysed. The five 4s 2 4p 4 ground levels and the ten 4s 2 4p 3 5s levels of previous analyses are confirmed in the first three spectra, except for revising in Y VI the 4p 4 1 S 0 and 4p 3 5s( 4 Ssub(3/2)) 2 levels and interchanging 5s( 2 Dsub(3/2)) 1 with 5s( 2 Dsub(3/2)) 2 . All level values are improved due to the new measurements. A new analysis of Mo IX establishing all the 4p 4 and 4p 3 5s levels is being reported. (Auth.)

Optical characteristics of BaGa2S4:Ho3+ and BaGa2Se4:Ho3+ single crystals

International Nuclear Information System (INIS)

Choe, Sung-Hyu; Jin, Moon-Seog; Kim, Wha-Tek

2005-01-01

BaGa 2 S 4 , BaGa 2 S 4 :Ho 3+ , BaGa 2 Se 4 , and BaGa 2 Se 4 :Ho 3+ single crystals were grown by using the chemical transport reaction method. The optical energy gaps of the single crystals were investigated in the temperature region from 11 K to 300 K. The temperature dependence of the optical energy gap was well fitted by the Varshni equation. Two broad emission bands were observed in the photoluminescence spectra of the single crystals. These bands were attributed to donor-acceptor pair recombinations. Sharp emission peaks were observed in the BaGa 2 S 4 :Ho 3+ and the BaGa 2 Se 4 :Ho 3+ single crystals and were assigned to radiation recombination between split Stark levels of Ho 3+ .

Family physics with S4 and Pati-Salam

NARCIS (Netherlands)

de Adelhart Toorop, R.

2010-01-01

Family symmetries and grand unified symmetries can bring more structure in the mass sector of the standard model and explain the patterns in the quarks’ and leptons’ masses and mixing. We discuss in particular a model with a Pati-Salam × S4 symmetry. This model can explain the observed neutrino

Consequences of Market-Based Measures CO2-emission Reduction Maritime Transport for the Netherlands; Gevolgen Market Based Measures CO2-emissiereductie zeevaart voor Nederland

Energy Technology Data Exchange (ETDEWEB)

Wortelboer-van Donselaar, P.; Kansen, M.; Moorman, S. [Kennisinstituut voor Mobiliteitsbeleid KiM, Den Haag (Netherlands); Faber, J.; Koopman, M.; Smit, M. [CE Delft, Delft (Netherlands)

2013-11-15

The introduction of Market Based Measures (MBMs) to reduce the CO2 emissions of international sea shipping will have relatively limited economic effects for the Netherlands. Moreover, these effects are largely in line with those in other countries. For the Netherlands, however, the manner in which MBMS are organised and enforced is likely to be particularly important, given the importance of ports to the Dutch economy, the country's relatively large bunker sector, and the fact that Dutch shipowners operate relatively small vessels and on a relatively small scale. MBMs include pricing measures in the form of tax or trade systems, as well as other market-related proposals. In this research study, the consequences are analysed of four international MBM proposals for the Netherlands [Dutch] Om de CO2-uitstoot van de internationale zeevaartsector terug te dringen worden momenteel zogeheten Market Based Measures (MBMs), zoals bijvoorbeeld het veilen van emissierechten of het invoeren van een heffing, overwogen. De invoering van de MBMs zal voor Nederland relatief beperkte economische effecten hebben. Deze effecten wijken bovendien niet bijzonder af van die voor andere landen. De wijze waarop de MBMs worden georganiseerd en gehandhaafd, is voor Nederland mogelijk wel van onderscheidend belang. Dit gezien het belang van de havens voor de Nederlandse economie, de relatief grote bunkersector, en de relatief kleine schepen en kleinschaligheid van de Nederlandse reders.

On the compactification of the moduli space of branched minimal immersions of S2 into S4

International Nuclear Information System (INIS)

Loo, B.

1992-01-01

We study the natural compactification of the moduli space of branched minimal immersions of S 2 into S 4 . We prove that the (compactified) moduli space M d is a connected projective variety of dimension 2d+4. It is irreducible when d=1,2, and it has two irreducible components when d ≥ 3. We discuss the bubbling phenomenon at the boundary of the moduli space. (author). 26 refs, 3 figs

Actes des Journees de linguistique (Proceedings of the Linguistics Conference) (6th, 1992).

Science.gov (United States)

Brousseau, Martin, Ed.; And Others

Papers, all in French, presented at a conference on linguistics include: "Machine Translation: Historic Aspects" (Ghada Attieh); "Translation and Conditioning" (Stephanie Bedard); "Semantic or Pre-Semantic Structures? From Perception to Causation" (Denise Belanger); "Presentation of Poetry Sung in Maroc"…

DIE MlllTERE BOUKUNS IN DIE NEDER. (1500-1800)~

African Journals Online (AJOL)

aatkundige verhoudings van die Middcleeue en faktore soos navwer tus3cn verskillende stcd'C, wrywings -met landshere c.d.m. in aanmerking gc~eem word, dan kan hieruit afgelei word dat stedelike militere aangeleenthede. 'n belang- rikc plek ...

Agrarische marketing: grondslagen en ontwikkelingen.

NARCIS (Netherlands)

Meulenberg, M.T.G.

1987-01-01

Een uiteenzetting over enkele grondslagen en de evolutie van agrarische marketing.Deze is een subdicipline van de algemene marketing theorie. Aandacht is geschonken aan de verschillen tussen beide sinds de vijftiger jaren. Het belang van verticale marktsystemen in agrarische marketing wordt

Linear thermal expansion coefficient of MgAl2O4(s)

International Nuclear Information System (INIS)

Dash, A.; Samui, P.; Naik, Y.P.; Chaudhary, Z.S.

2011-01-01

The coefficient of linear thermal expansion (α av ) of MgAl 2 O 4 (s) has been determined using a Netzsch 402 PC dilatometer with Al 2 O 3 (s) as the push-rod. The change in length per unit length was recorded as a function of temperature between room temperature to 1273 K at a heating rate of 8 K.min /1 , in argon flowing atmosphere. The average of three measurements was quoted as the α av for MgAl 2 O 4 (s). The linear thermal expansion was measured to an accuracy of ±3%. (author)

Electric field effect on the emission rate of H4F and H4S hole traps in InP

International Nuclear Information System (INIS)

Darwich, R.; Alek, B.

2010-01-01

The electric field effect on the emission rate enhancement of the H4 F and H4 S hole trap in highly Zn-doped InP has been examined using the deep level transient spectroscopy (DLTS) and double correlation DLTS (DDLTS). The DLTS and DDLTS results have been found to be in good agreement for low and intermediate electric fields, but they disagree for large field effect. Comparing our emission data with the theory, we have found that H4 F obeys the quantum model of phonon-assisted tunneling while H4 S follows the Poole-Frenkel model employing a three-dimensional screening coulombic potential. Our results show that the H4 S defect can be attributed to a charged (V p - Zn) complex. (author)

Electrical properties of FeGa2S4

International Nuclear Information System (INIS)

Niftiev, N.N.; Alidzhanov, M.A.; Tagiev, O.B.; Mamedov, F.M.

2004-01-01

Temperature dependence of the electrical conductivity and current-voltage characteristics (CVCs) of FeGa 2 S 4 crystals have been studied. It has been shown that the current in the nonlinear range of CVCs is caused by the field effect. The activation energy of carriers and the trap concentrations have been determined

Enzyme-linked immunosorbent serum assay specific for the 7S domain of Collagen Type IV (P4NP 7S)

DEFF Research Database (Denmark)

Leeming, Diana J; Nielsen, Mette J; Dai, Yueqin

2012-01-01

Aim:  The present study describes the ability of a newly developed N-terminal pro-peptides of type IV collagen 7S domain (P4NP 7S) competitive enzyme-linked immunosorbent assay (ELISA) for describing liver fibrosis. The assay applies a monoclonal antibody specific for a PIVNP 7S epitope 100...... were significantly elevated in rat with liver fibrosis as seen by histology (CCL4: 283% elevated in the highest quartile of total hepatic collagen compared with controls, P = 0.001; BDL: 183% elevated at week 4 compared with sham, P type IV collagen...... expression in BDL rats (r = 0.49, P serum assay specific for P4NP 7S was highly related to liver fibrosis...

Supersymmetric black holes in AdS4 from very special geometry

International Nuclear Information System (INIS)

Gnecchi, Alessandra; Halmagyi, Nick

2014-01-01

Supersymmetric black holes in AdS spacetime are inherently interesting for the AdS/CFT correspondence. Within a four dimensional gauged supergravity theory coupled to vector multiplets, the only analytic solutions for regular, supersymmetric, static black holes in AdS 4 are those in the STU-model due to Cacciatori and Klemm. We study a class of U(1)-gauged supergravity theories coupled to vector multiplets which have a cubic prepotential, the scalar manifold is then a very special Kähler manifold. When the resulting very special Kähler manifold is a homogeneous space, we find analytic solutions for static, supersymmetric AdS 4 black holes with vanishing axions. The horizon geometries of our solutions are constant curvature Riemann surfaces of arbitrary genus

IR, FT-ICR-MS studies on (1'S, 6'S)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0] non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride salt.

Science.gov (United States)

Lin, Zhiwei

2014-01-01

The infrared spectra of (1'S, 6'S)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0] non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride salt (CLF-HCl) were studied and compared with free base. Their fragmentation pathways were investigated using tandem mass spectrometric (MS/MS) techniques on Fourier-transform ion cyclotron resonance spectrum, and many characteristic fragment ions were found. Copyright © 2013 Elsevier B.V. All rights reserved.

Structure determination of two structural analogs, named 3-[1-(2-fluoro-4-biphenyl)ethyl]-6-(4-fluorophenyl)-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole (C23H16F2N4S) and 3-[1-(2-fluoro-4-biphenyl)ethyl]-6-(4-chlorophenyl)-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole (C23H16ClFN4S) by synchrotron X-ray powder diffraction

Energy Technology Data Exchange (ETDEWEB)

Gündoğdu, Gülsüm; Aytaç, Sevim Peri; Müller, Melanie; Tozkoparan, Birsen; Kaynak, Filiz Betül

2017-12-01

Two novel compounds, 3-[1-(2-fluoro-4-biphenyl)ethyl]-6-(4-fluorophenyl)-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole (C₂₃H₁₆F₂N₄S) (1) and 3-[1-(2-fluoro-4-biphenyl)ethyl]-6-(4-chlorophenyl)-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole (C₂₃H₁₆ClFN₄S) (2), have been designed and synthesized as cytotoxic agents. The compounds were characterized by infrared, proton nuclear magnetic resonance, mass spectral data, elemental analysis and X-ray powder diffraction. The present study comprises spectral data and crystal structures of these novel compounds determined from synchrotron X-ray powder diffraction data. The structure solutions were obtained by simulated annealing. The final structures were achieved by Rietveld refinement using soft restraints for all bond lengths, bond angles, and planar groups. Both compounds crystallize in space groupS0885715617001105_inline1' mime-subtype='gif' type='simple'/>$P\\bar 1$,Z= 2, with the unit-cell parametersa= 6.37433(9),b= 11.3641(2),c= 14.09115(19) Å,α= 80.1740(8)°,β= 85.1164(8)°,γ= 80.9831(10)°,V= 991.55(3) ųof compound (1) anda= 6.53736(6),b= 11.55725(15),c= 14.01373(13) Å,α= 80.3323(7)°,β= 84.8939(6)°,γ= 79.3954(8)°,V= 1024.08(2) ųof compound (2). Structural analyses reveal that the title compounds are isostructural.

Real-Time 200 Gb/s (4x56.25 Gb/s) PAM-4 Transmission over 80 km SSMF using Quantum-Dot Laser and Silicon Ring-Modulator

DEFF Research Database (Denmark)

Eiselt, Nicklas; Griesser, Helmut; Eiselt, Michael

2017-01-01

We report real-time 4x56.26-Gb/s DWDM PAM-4 transmission over 80-km SSMF with novel optical transmitter sub-assembly comprising multi-wavelength quantum-dot laser and silicon ring modulators. Pre-FEC BERs below 1E-4 are achieved after 80-km, allowing error-free operation with HD-FEC...

Simplifying superstring and D-brane actions in AdS4 x CP3 superbackground

International Nuclear Information System (INIS)

Grassi, Pietro Antonio; Sorokin, Dmitri; Wulff, Linus

2009-01-01

By making an appropriate choice for gauge fixing kappa-symmetry we obtain a relatively simple form of the actions for a D = 11 superparticle in AdS 4 x S 7 /Z k , and for a D0-brane, fundamental string and D2-branes in the AdS 4 x CP 3 superbackground. They can be used to study various problems of string theory and the AdS 4 /CFT 3 correspondence, especially in regions of the theory which are not reachable by the OSp(6|4)/U(3) x SO(1,3) supercoset sigma-model. In particular, we present a simple form of the gauge-fixed superstring action in AdS 4 x CP 3 and briefly discuss issues of its T-dualization.

Crystal structure and magnetic properties of LaCa0.143 (4O0.857 (4F0.143 (4Bi0.857 (4S2

Directory of Open Access Journals (Sweden)

Rongtie Huang

2016-06-01

Full Text Available The synthesis, structure, and magnetic properties of lithium dibarium calcium oxide fluoride disulfide are reported. LaCa0.143 (4O0.857 (4F0.143 (4Bi0.857 (4S2 crystallizes in the tetragonal space group P4/nmm. The structure exhibits disorder of the Ca2+ and Bi3+ cations, and the O2− and F− anions. The structure is composed of a stacking of [(O,F2La2] layers and double [(Bi,CaS2] layers. Magnetic property measurements indicate a very small magnetization at 300 K and the existence of weak ferromagnetism at 2 K.

FAM107B is regulated by S100A4 and mediates the effect of S100A4 on the proliferation and migration of MGC803 gastric cancer cells.

Science.gov (United States)

Guo, Junfu; Bian, Yue; Wang, Yu; Chen, Lisha; Yu, Aiwen; Sun, Xiuju

2017-10-01

FAM107B expression was decreased in stomach cancer and many other kinds of cancer. The forced expression of FAM107B in HeLa cells diminished proliferation in response to growth factors, suggesting that FAM107B might play important roles in many types of cancers. But the mechanisms underlying the decreased expression of FAM107B in cancers are not clear, the functional significance needs to be further clarified. Our previous findings from cDNA microarray showed that there are 179 differentially expressed genes after S100A4 inhibition in gastric cancer cells MGC803. FAM107B was an upregulated one among them. In the present study, we confirmed that FAM107B expression was upregulated in MGC803 cells after S100A4 inhibition by qRT-PCR. We demonstrated for the first time that FAM107B was downregulated by S100A4. The results from CCK-8 and transwell assay showed that FAM107B inhibition by siRNA led to significantly increased proliferation and migrating abilities of MGC803 cells, respectively, indicating that FAM107B plays important roles in inhibiting the proliferation and migration of MGC803 cells. The rescue experiment showed that FAM107B-siRNA transfection reversed the reduced proliferation and migration abilities induced by S100A4 inhibition in the cells. These findings suggest that, as a downstream effector, FAM107B at least partly mediates the effect of S100A4 on the proliferation and migration of MGC803 cells. In conclusion, we first provide experimental evidence suggesting that FAM107B was downregulated by S100A4 in gastric cancer MGC803 cells. And FAM107B at least partially mediates the biological effect of S100A4 in the cells. © 2017 International Federation for Cell Biology.

Precision spectroscopy of the 2S-4P transition in atomic hydrogen

Science.gov (United States)

Maisenbacher, Lothar; Beyer, Axel; Matveev, Arthur; Grinin, Alexey; Pohl, Randolf; Khabarova, Ksenia; Kolachevsky, Nikolai; Hänsch, Theodor W.; Udem, Thomas

2017-04-01

Precision measurements of atomic hydrogen have long been successfully used to extract fundamental constants and to test bound-state QED. However, both these applications are limited by measurements of hydrogen lines other than the very precisely known 1S-2S transition. Moreover, the proton r.m.s.charge radius rp extracted from electronic hydrogen measurements currently disagrees by 4 σ with the much more precise value extracted from muonic hydrogen spectroscopy. We have measured the 2S-4P transition in atomic hydrogen using a cryogenic beam of hydrogen atoms optically excited to the initial 2S state. The first order Doppler shift of the one-photon 2S-4P transition is suppressed by actively stabilized counter-propagating laser beams and time-of-flight resolved detection. Quantum interference between excitation paths can lead to significant line distortions in our system. We use an experimentally verified, simple line shape model to take these distortions into account. With this, we can extract a new value for rp and the Rydberg constant R∞ with comparable accuracy as the combined previous H world data.

Trithallium tetraselenophosphate Tl3PSe4, and trithallium tetrathioarsenate, Tl3AsS4, by neutron time-of-flight diffraction

International Nuclear Information System (INIS)

Alkire, R.W.; Vergamini, P.J.; Larson, A.C.; Morosin, B.

1984-01-01

Room-temperature (293 K) single-crystal structure determinations of the isostructural materials Tl 3 PSe 4 and Tl 3 AsS 4 were performed at the Los Alamos National Laboratory Pulsed Neutron Facility. For Tl 3 PSe 4 : Msub(r) = 959.92, Pcmn, a = 9.276 (1), b = 11.036 (2), c = 9.058 (1) A, V = 927.27 A 3 , Z = 4, Dsub(m) = 6.87 (2), Dsub(x) = 6.876 Mg m -3 , lambdasub(neutron) = 0.5 → 5.2 A, F(000) = 252.5 fm. For Tl 3 AsS 4 : Msub(r) = 816.29, Pcmn, a = 9.084 (3), b = 10.877 (3), c = 8.877 (3) A, V = 877.11 A 3 , Z = 4, Dsub(m) = 6.18 (2), Dsub(x) = 6.181 Mg m -3 , lambdasub(neutron) = 0.5 → 5.2 A, F(000) = 177.2 fm. For Tl 3 PSe 4 (Tl 3 AsS 4 ), 1929 (1013) reflections were measured with I > 3sigma(I) and refined by full-matrix least squares to R(F) = 0.061 (0.063). Results on atomic refinement from this study represent an order of magnitude increase in precision over previous single-crystal X-ray structural work using Mo Kα radiation. The PSe 4 3- (AsS 4 3- ) groups have essentially tetrahedral configurations and one Tl + ion shows large anisotropic thermal motion which is structure related. (Auth.)

Phase relations in the quasi-binary Cu{sub 2}GeS{sub 3}-ZnS and quasi-ternary Cu{sub 2}S-Zn(Cd)S-GeS{sub 2} systems and crystal structure of Cu{sub 2}ZnGeS{sub 4}

Energy Technology Data Exchange (ETDEWEB)

Parasyuk, O.V. [Department of General and Inorganic Chemistry, Volyn State University, Voli Ave 13, 43009 Lutsk (Ukraine)]. E-mail: oleg@lab.univer.lutsk.ua; Piskach, L.V. [Department of General and Inorganic Chemistry, Volyn State University, Voli Ave 13, 43009 Lutsk (Ukraine); Romanyuk, Y.E. [Advanced Photonics Laboratory, Institute of Imaging and Applied Optics, Ecole Polytechnique Federale de Lausanne, CH-1015 Lausanne (Switzerland); Olekseyuk, I.D. [Department of General and Inorganic Chemistry, Volyn State University, Voli Ave 13, 43009 Lutsk (Ukraine); Zaremba, V.I. [Department of Inorganic Chemistry, Ivan Franko National University of Lviv, 6 Kyryla and Mefodiya Str., 79005 L' viv (Ukraine); Pekhnyo, V.I. [V.I. Vernadskii Institute of General and Inorganic Chemistry, Ukrainian National Academy of Sciences, Palladina Ave 32-34, 03680 Kiev (Ukraine)

2005-07-19

The isothermal section of the Cu{sub 2}S-Zn(Cd)S-GeS{sub 2} systems at 670K was constructed using X-ray diffraction analysis. At this temperature, two quaternary intermediate phases, Cu{sub 2}CdGeS{sub 4} and {approx}Cu{sub 8}CdGeS{sub 7}, exist in the Cu{sub 2}S-CdS-GeS{sub 2} system, and only one phase, Cu{sub 2}ZnGeS{sub 4}, exists in the Cu{sub 2}S-ZnS-GeS{sub 2} system. The phase diagram of the Cu{sub 2}GeS{sub 3}-ZnS system was constructed using differential-thermal analysis and X-ray diffraction, and the existence of Cu{sub 2}ZnGeS{sub 4} has been confirmed. It forms incongruently at 1359K. Powder X-ray diffraction was used to refine the crystal structure of Cu{sub 2}ZnGeS{sub 4}, which crystallizes in the tetragonal stannite-type structure at 670K (space group I4-bar 2m, a=0.534127(9)nm, c=1.05090(2)nm, R{sub I}=0.0477). The possibility of the formation of quaternary compounds in the quasi-ternary systems A{sup I}{sub 2}X-B{sup II}X-C{sup IV}X{sub 2}, where A{sup I}-Cu, Ag; B{sup II}-Zn, Cd, Hg; C{sup IV}-Si, Ge, Sn and X-S, Se, Te is discussed.

MoS_2/reduced graphene oxide hybrid with CdS nanoparticles as a visible light-driven photocatalyst for the reduction of 4-nitrophenol

International Nuclear Information System (INIS)

Peng, Wen-chao; Chen, Ying; Li, Xiao-yan

2016-01-01

Highlights: • MoS_2/rGO hybrid is synthesized using a one-step hydrothermal method. • MoS_2/rGO hybrid is used as the support and cocatalyst for CdS nanoparticles. • CdS-MoS_2/rGO composite is effective photocatalyst for 4-NP reduction in visible light. • Ammonium formate is an effective sacrificial agent for 4-NP photocatalytic reduction. - Abstract: Photocatalytic reduction of nitroaromatic compounds to aromatic amines using visible light is an attractive process that utilizes sunlight as the energy source for the chemical conversions. Herewith we synthesized a composite material consisting of CdS nanoparticles grown on the surface of MoS_2/reduced graphene oxide (rGO) hybrid as a novel photocatalyst for the reduction of 4-nitrophenol (4-NP). The CdS-MoS_2/rGO composite is shown as a high-performance visible light-driven photocatalyst. Even without a noble-metal cocatalyst, the catalyst exhibited a great activity under visible light irradiation for the reduction of 4-NP to much less toxic 4-aminophenol (4-AP) with ammonium formate as the sacrificial agent. Composite CdS-0.03(MoS_2/0.01rGO) was found to be the most effective photocatalyst for 4-NP reduction. The high photocatalytic performance is apparently resulted from the synergetic functions of MoS_2 and graphene in the composite, i.e. the cocatalysts serve as both the active adsorption sites for 4-NP and electron collectors for the separation of electron-hole pairs generated by CdS nanoparticles. The laboratory results show that the CdS-MoS_2/rGO composite is a low-cost and stable photocatalyst for effective reduction and detoxification of nitroaromatic compounds using solar energy.

Is NiCo2S4 really a semiconductor?

KAUST Repository

Xia, Chuan; Li, Peng; Gandi, Appala; Schwingenschlö gl, Udo; Alshareef, Husam N.

2015-01-01

NiCo2S4 is a technologically important electrode material that has recently achieved remarkable performance in pseu-docapacitor, catalysis, and dye-synthesized solar cell applications.[1-5] Essentially, all reports on this material have pre

MAu2GeS4-Chalcogel (M = Co, Ni): Heterogeneous Intra- and Intermolecular Hydroamination Catalysts

KAUST Repository

Davaasuren, Bambar

2017-08-08

High surface area macroporous chalcogenide aerogels (chalcogels) MAu2GeS4 (M = Co, Ni) were prepared from K2Au2GeS4 precursor and Co(OAc)2 or NiCl2 by one-pot sol-gel metathesis reactions in aqueous media. The MAu2GeS4-chalcogels were screened for catalytic intramolecular hydroamination of 4-pentyn-1-amine substrate at different temperatures. 87% and 58% conversion was achieved at 100 °C, using CoAu2GeS4- and NiAu2GeS4-chalcogels respectively, and the reaction kinetics follows the first order. It was established that the catalytic performance of the aerogels is associated with the M(2+) centers present in the structure. Intermolecular hydroamination of aniline with 1-R-4-ethynylbenzene (R = -H, -OCH3, -Br, -F) was carried out at 100 °C using CoAu2GeS4-chalcogel catalyst, due to its promising catalytic performance. The CoAu2GeS4-chalcogel regioselectively converted the pair of substrates to respective Markovnikov products, (E)-1-(4-R-phenyl)-N-phenylethan-1-imine, with 38% to 60% conversion.

MAu2GeS4-Chalcogel (M = Co, Ni): Heterogeneous Intra- and Intermolecular Hydroamination Catalysts

KAUST Repository

Davaasuren, Bambar; Emwas, Abdul-Hamid M.; Rothenberger, Alexander

2017-01-01

High surface area macroporous chalcogenide aerogels (chalcogels) MAu2GeS4 (M = Co, Ni) were prepared from K2Au2GeS4 precursor and Co(OAc)2 or NiCl2 by one-pot sol-gel metathesis reactions in aqueous media. The MAu2GeS4-chalcogels were screened for catalytic intramolecular hydroamination of 4-pentyn-1-amine substrate at different temperatures. 87% and 58% conversion was achieved at 100 °C, using CoAu2GeS4- and NiAu2GeS4-chalcogels respectively, and the reaction kinetics follows the first order. It was established that the catalytic performance of the aerogels is associated with the M(2+) centers present in the structure. Intermolecular hydroamination of aniline with 1-R-4-ethynylbenzene (R = -H, -OCH3, -Br, -F) was carried out at 100 °C using CoAu2GeS4-chalcogel catalyst, due to its promising catalytic performance. The CoAu2GeS4-chalcogel regioselectively converted the pair of substrates to respective Markovnikov products, (E)-1-(4-R-phenyl)-N-phenylethan-1-imine, with 38% to 60% conversion.

Phase controlled solvothermal synthesis of Cu{sub 2}ZnSnS{sub 4}, Cu{sub 2}ZnSn(S,Se){sub 4} and Cu{sub 2}ZnSnSe{sub 4} Nanocrystals: The effect of Se and S sources on phase purity

Energy Technology Data Exchange (ETDEWEB)

Pal, Mou [Instituto de Energías Renovables, Universidad Nacional Autónoma de México, 62580 Temixco, Morelos (Mexico); Instituto de Física, BUAP, Av. San Claudio y Blvd. 18 Sur Col. San Manuel, Ciudad Universitaria, C.P. 72570, Puebla (Mexico); Mathews, N.R. [Instituto de Energías Renovables, Universidad Nacional Autónoma de México, 62580 Temixco, Morelos (Mexico); Paraguay-Delgado, F. [Departamento de Materiales Nanoestructurados, Centro de Investigación en Materiales Avanzados (CIMAV), Chihuahua (Mexico); Mathew, X., E-mail: xm@ier.unam.mx [Instituto de Energías Renovables, Universidad Nacional Autónoma de México, 62580 Temixco, Morelos (Mexico)

2015-09-15

In this study, we have reported the synthesis of Cu{sub 2}ZnSnSe{sub 4} (CZTSe), Cu{sub 2}ZnSnS{sub 4} (CZTS) and Cu{sub 2}ZnSn(S,Se){sub 4} (CZTSSe) nanocrystals with tunable band gap and composition obtained by solvothermal method. The crystalline structure, composition, morphology and optical properties of the nanoparticles were characterized by X-ray diffraction (XRD), Raman scattering, energy dispersive X-ray spectroscopy, transmission electron microscopy and diffuse reflectance (DR) spectroscopy. While the XRD patterns of CZTS and CZTSe nanoparticles prepared with elemental S/Se powder revealed the presence of phase pure nanoparticles, the CZTSSe nanoparticles obtained using a mixture of S and Se, were found to contain many secondary phases under the same synthesis protocol. Formation of impurity phases in CZTSSe sample, can be avoided by using a mixture of 1-dodecanethiol (DT; CH{sub 3}(CH{sub 2}){sub 11}SH)/oleylamine (OLA) instead of S powder and following the same experimental procedure. The incorporation of S in CZTSe nanocrystals prepared in presence of DDT/OLA mixture was confirmed through structural and optical characterizations. The optical properties of the quaternary chalcogenide nanocrystals were found to vary with the chemical composition of the material. - Highlights: • Solvothermal synthesis of CZTS, CZTSSe and CZTSe nanocrystals and discussion on possible formation mechanism. • Use of dodecanethiol/oleylamine mixture to synthesize phase-pure CZTSSe nanocrystals. • Formation of impurity phases can be controlled with proper S and Se sources.

Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor.

Science.gov (United States)

Onuma, Takashi; Tanabe, Kumiko; Kito, Yuko; Tsujimoto, Masanori; Uematsu, Kodai; Enomoto, Yukiko; Matsushima-Nishiwaki, Rie; Doi, Tomoaki; Nagase, Kiyoshi; Akamatsu, Shigeru; Tokuda, Haruhiko; Ogura, Shinji; Iwama, Toru; Kozawa, Osamu; Iida, Hiroki

2017-08-01

Sphingosine 1-phosphate (S1P) is as an extracellular factor that acts as a potent lipid mediator by binding to specific receptors, S1P receptors (S1PRs). However, the precise role of S1P in human platelets that express S1PRs has not yet been fully clarified. We previously reported that heat shock protein 27 (HSP27) is released from human platelets accompanied by its phosphorylation stimulated by collagen. In the present study, we investigated the effect of S1P on the collagen-induced platelet activation. S1P pretreatment markedly attenuated the collagen-induced aggregation. Co-stimulation with S1P and collagen suppressed collagen-induced platelet activation, but the effect was weaker than that of S1P-pretreatment. The collagen-stimulated secretion of platelet-derived growth factor (PDGF)-AB and the soluble CD40 ligand (sCD40L) release were significantly reduced by S1P. In addition, S1P suppressed the collagen-induced release of HSP27 as well as the phosphorylation of HSP27. S1P significantly suppressed the collagen-induced phosphorylation of p38 mitogen-activated protein kinase. S1P increased the levels of GTP-bound Gαi and GTP-bound Gα13 coupled to S1PPR1 and/or S1PR4. CYM50260, a selective S1PR4 agonist, but not SEW2871, a selective S1PR1 agonist, suppressed the collagen-stimulated platelet aggregation, PDGF-AB secretion and sCD40L release. In addition, CYM50260 reduced the release of phosphorylated-HSP27 by collagen as well as the phosphorylation of HSP27. The selective S1PR4 antagonist CYM50358, which failed to affect collagen-induced HSP27 phosphorylation, reversed the S1P-induced attenuation of HSP27 phosphorylation by collagen. These results strongly suggest that S1P inhibits the collagen-induced human platelet activation through S1PR4 but not S1PR1. Copyright © 2017 Elsevier Ltd. All rights reserved.

Voeding en parodontitis

NARCIS (Netherlands)

van der Velden, U.

2013-01-01

Parodontitis is een multicausale aandoening waarbij vele verschillende factoren een rol spelen. Naast de bekende risicofactoren/indicatoren zoals roken en stress, blijkt ook het dieet van belang. Van oudsher is de relatie bekend tussen vitamine C en parodontale aandoeningen door het optreden van

ESR en IPSAS: harmonisering van financiële verslaggeving door overheden

NARCIS (Netherlands)

van Schaik, F.; Haakman, L.

2012-01-01

De Europese statistische regels voor overheden, van belang voor onder andere het bepalen van tekort en schuld volgens de EMU-normen, en internationale jaarrekeningregels van overheden, hebben vele overeenkomsten: het zijn beide baten-lastenstelsels en ze brengen verslag uit over dezelfde transacties

Koppelen en ontkoppelen; milieupolitieke modernisering in een tijdperk van globalisering

NARCIS (Netherlands)

Mol, A.P.J.

2001-01-01

Een bijdrage over de modernisering van het milieubeleid in Nederland en Europa sinds 1970, waarbij de processen worden onderscheiden die van belang zijn om deze modernisering te realiseren. Rede, uitgesproken ␛bij de aanvaarding van het ambt van hoogleraar in het milieubeleid (Wageningen)

PKI als veilig communicatiemiddel

NARCIS (Netherlands)

Spek, J. van der; Veugen, P.J.M.

2002-01-01

Het belang van betrouwbare elektronische communicatie neemt hand over hand toe. Niet alleen in de context van gesloten oplossingen in bedrijfsleven of overheid, maar in toenemende mate ook in open omgevingen tussen partijen die niet van tevoren contractueel met elkaar zijn verbonden. Belangrijke

Selectie en genetische variatie in een fokprogramma

NARCIS (Netherlands)

Oldenbroek, Kor; Maurice - Van Eijndhoven, Myrthe

2015-01-01

In drie voorgaande artikelen in deze serie zijn achtereenvolgens het fokdoel, de registratie van gegevens en de basisprincipes van de erfelijkheid besproken. In dit laatste artikel wordt het belang van genetische variatie en de selectie van ouderdieren besproken. Twee belangrijke elementen in het

Management, organisatie en ons brein

NARCIS (Netherlands)

Commandeur, H.R.; Man, de H.; Meché, van der F.

2012-01-01

Recente ontwikkelingen in de neurowetenschappen zijn van belang voor management en organisatie. Vooronderstellingen over menselijk gedrag op dit gebied moeten mogelijk worden bijgesteld in het licht van de snelle ontwikkeling van neurowetenschappelijk onderzoek. Dat is een reden voor M&O om met een

Conferentie onderzoekend & ontwerpend leren

NARCIS (Netherlands)

Steenbeek, Henderien

2015-01-01

De rol van talent en verwondering in W&T-onderwijs.

Deze keynote gaat over het belang van verwondering & het stimuleren van talent bij Wetenschap & Techniek in de PABO. Bij Conferentie Onderzoekend & ontwerpend leren op de PABO (21 september 2015).

Rac1 meets ubiquitin: New insights in Rac1 signalling

NARCIS (Netherlands)

Nethe, M.

2011-01-01

Het cytoskelet bestaat uit eiwitketens (polymeren), waarvan de lengte fluctueren. Het functioneert onder andere als ‘wegennet’ en reguleert het transport van eiwitten naar specifieke plaatsen binnen de cel. Een aantal eiwitten is van belang voor celbeweging, waaronder Rac1. Micha Nethe beschrijft

Vloeruitvoering en type rooster KOH

NARCIS (Netherlands)

Hoofs, A.

1991-01-01

Het verbeteren van het kraamopfokhok is op het Varkensproefbedrijf in Sterksel een belang rijk punt van onderzoek. Er wordt vooral gestreefd naar verlaging van de biggensterfte. uit onderzoeksresultaten blijkt dat als het totale vloeroppervlak van hetkraamopfokhok optimaal afgestemd is op het dier

Continuous quality improvement based on Lean Six Sigma in manufacturing small and medium sized enterprises

NARCIS (Netherlands)

Timans, Werner

2014-01-01

Kleine en middelgrote bedrijven uit de maakindustrie ervaren toenemende eisen met betrekking tot de kwaliteit van producten en processen. Om in competitie te blijven is voortdurend verbeteren van cruciaal belang, en de Lean Six Sigma benadering biedt veelbelovende mogelijkheden om continu verbeteren

Effectiviteit van een klassieke Crew Resource Management training in de Intensive Care: een gecontroleerde studie.

NARCIS (Netherlands)

Kemper, P.F.; Bruijne, M. de; Dyck, C. van; So, K.L.; Tangkau, P.; Wagner, C.

2013-01-01

Achtergrond: Er is een toenemende bewustwording dat onbedoelde zorg gerelateerde schade in de gezondheidszorg vaker voortvloeit uit problemen met niet-technische vaardigheden, dan door een gebrek in technische, of klinische, vaardigheden. Dit is vooral van belang in de Intensive Care (IC), waar

Tropospheric Ozone Research: Monitoring and modelling of photo-oxidants over Europe

NARCIS (Netherlands)

Beck JP; Roemer MGM; Vosbeek MEJP; Builtjes PJH; RIVM-LLO; TNO-MEP; KEMA

1996-01-01

Het EUROTRAC-TOR programma is opgezet om chemische- en transportprocessen, die van belang zijn voor het optreden van foto-oxidantia in Europa te bestuderen. Kernvraag is: "welke rol spelen emissies in Europa en welke resultaten kunnen beleidsmatig maximaal behaald worden?". In het

A Performance-Based Comparison of Object-Oriented Simulation Tools

Science.gov (United States)

1992-04-01

simulation" [Belanger 90a, 90b]. CACI Products Company markets MODSIM II as the commercial version of ModSim, which was created on a US Army contract...aim fprintf (report_file, "Line Statistics\\ nLine teller repoirt.cust interrupts; Lengt~is\

Biofeedback. Psychofysiologische en leertheoretische aspecten

NARCIS (Netherlands)

Bakker, Schelte Jan

1978-01-01

Het voornaamste uitgangspunt van deze studie was de gecompliceerdheid van biofeedback, waarin diverse psychologische en psychofysiologische processen een rol spelen. Het belang van theorie-ontwikkeling- ook ten behoeve van toepassingen van de biofeedback- werd uiteengezet en de nadruk lag dan ook op

The s-process enrichment of the globular clusters M4 and M22

Energy Technology Data Exchange (ETDEWEB)

Shingles, Luke J.; Karakas, Amanda I.; Fishlock, Cherie K.; Yong, David; Da Costa, Gary S.; Marino, Anna F. [Research School of Astronomy and Astrophysics, Australian National University, Canberra, ACT 2611 (Australia); Hirschi, Raphael, E-mail: luke.shingles@anu.edu.au [Institute for the Physics and Mathematics of the Universe (WPI), University of Tokyo, 5-1-5 Kashiwanoha, 277-8583 Kashiwa (Japan)

2014-11-01

We investigate the enrichment in elements produced by the slow neutron-capture process (s-process) in the globular clusters M4 (NGC 6121) and M22 (NGC 6656). Stars in M4 have homogeneous abundances of Fe and neutron-capture elements, but the entire cluster is enhanced in s-process elements (Sr, Y, Ba, Pb) relative to other clusters with a similar metallicity. In M22, two stellar groups exhibit different abundances of Fe and s-process elements. By subtracting the mean abundances of s-poor from s-rich stars, we derive s-process residuals or empirical s-process distributions for M4 and M22. We find that the s-process distribution in M22 is more weighted toward the heavy s-peak (Ba, La, Ce) and Pb than M4, which has been enriched mostly with light s-peak elements (Sr, Y, Zr). We construct simple chemical evolution models using yields from massive star models that include rotation, which dramatically increases s-process production at low metallicity. We show that our massive star models with rotation rates of up to 50% of the critical (break-up) velocity and changes to the preferred {sup 17}O(α, γ){sup 21}Ne rate produce insufficient heavy s-elements and Pb to match the empirical distributions. For models that incorporate asymptotic giant branch yields, we find that intermediate-mass yields (with a {sup 22}Ne neutron source) alone do not reproduce the light-to-heavy s-element ratios for M4 and M22, and that a small contribution from models with a {sup 13}C pocket is required. With our assumption that {sup 13}C pockets form for initial masses below a transition range between 3.0 and 3.5 M {sub ☉}, we match the light-to-heavy s-element ratio in the s-process residual of M22 and predict a minimum enrichment timescale of between 240 and 360 Myr. Our predicted value is consistent with the 300 Myr upper limit age difference between the two groups derived from isochrone fitting.

Comparative assessment of saliva and plasma for drug bioavailability and bioequivalence studies in humans

Directory of Open Access Journals (Sweden)

Nasir M. Idkaidek

2017-07-01

Conclusion: Our results suggest that there is a potential in BA/BE studies for saliva to be considered as a surrogate for plasma concentration, which goes along with drug regulations. The use of saliva instead of plasma in such studies makes them non-invasive, easy and with a lower clinical burden.

Distributed Simulation in Industry

NARCIS (Netherlands)

C.A. Boer (Csaba)

2005-01-01

textabstractCsaba Attila Boer was born in Satu Mare, Romania, on 29 October, 1975. He completed his secondary education at Kölcsey Ferenc High School, in Satu Mare, in 1994. In the same year he started his higher education at Babeş-Bolyai University, Faculty of Mathematics and Computer Science,

Flavor S4xZ2 symmetry and neutrino mixing

International Nuclear Information System (INIS)

Zhang He

2007-01-01

We present a model of the lepton masses and flavor mixing based on the discrete group S 4 xZ 2 . In this model, all the charged leptons and neutrinos are assigned to the 3 - b arα representation of S 4 in the Yamanouchi bases. The charged lepton and neutrino masses are mainly determined by the vacuum expectation value structures of the Higgs fields. A nearly tri-bimaximal lepton flavor mixing pattern, which is in agreement with the current experimental results, can be accommodated in our model. The neutrino mass spectrum takes the nearly degenerate pattern, and thus can be well tested in the future precise experiments

Insight into a conformation of the PNA-PNA duplex with (2‧R,4‧R)- and (2‧R,4‧S)-prolyl-(1S,2S)-2-aminocyclopentanecarboxylic acid backbones

Science.gov (United States)

Maitarad, Amphawan; Poomsuk, Nattawee; Vilaivan, Chotima; Vilaivan, Tirayut; Siriwong, Khatcharin

2018-04-01

Suitable conformations for peptide nucleic acid (PNA) self-hybrids with (2‧R,4‧R)- and (2‧R,4‧S)-prolyl-(1S,2S)-2-aminocyclopentanecarboxylic acid backbones (namely, acpcPNA and epi-acpcPNA, respectively) were investigated based on molecular dynamics simulations. The results revealed that hybridization of the acpcPNA was observed only in the parallel direction, with a conformation close to the P-type structure. In contrast, self-hybrids of the epi-acpcPNA were formed in the antiparallel and parallel directions; the antiparallel duplex adopted the B-form conformation, and the parallel duplex was between B- and P-forms. The calculated binding energies and the experimental data indicate that the antiparallel epi-acpcPNA self-hybrid was more stable than the parallel duplex.

USGS library for S-PLUS for Windows -- Release 4.0

Science.gov (United States)

Lorenz, David L.; Ahearn, Elizabeth A.; Carter, Janet M.; Cohn, Timothy A.; Danchuk, Wendy J.; Frey, Jeffrey W.; Helsel, Dennis R.; Lee, Kathy E.; Leeth, David C.; Martin, Jeffrey D.; McGuire, Virginia L.; Neitzert, Kathleen M.; Robertson, Dale M.; Slack, James R.; Starn, J. Jeffrey; Vecchia, Aldo V.; Wilkison, Donald H.; Williamson, Joyce E.

2011-01-01

Release 4.0 of the U.S. Geological Survey S-PLUS library supercedes release 2.1. It comprises functions, dialogs, and datasets used in the U.S. Geological Survey for the analysis of water-resources data. This version does not contain ESTREND, which was in version 2.1. See Release 2.1 for information and access to that version. This library requires Release 8.1 or later of S-PLUS for Windows. S-PLUS is a commercial statistical and graphical analysis software package produced by TIBCO corporation(http://www.tibco.com/). The USGS library is not supported by TIBCO or its technical support staff.

Convenient synthesis of Mn-doped Zn (O,S) nanoparticle photocatalyst for 4-nitrophenol reduction

Science.gov (United States)

Susanto Gultom, Noto; Abdullah, Hairus; Kuo, Dong-Hau

2018-04-01

The conversion of 4-nitrophenol as a toxic and waste pollutant to 4-aminophenol as a non-toxic and useful compound by photocatalytic reduction is highly important. In this work, the solid-solution concept by doping was involved to synthesis earth-abundant and green material of Mn-doped Zn(O,S). Zn(O,S) with different Mn doping contents was easily synthesized at low temperature 90°C for 4-NP reduction without using the reducing agent of NaBH4. The Mn-doped Zn(O,S) catalyst exhibited the enhancements in optical and electrochemical properties compared to un-doped Zn(O,S).It was found that 10% Mn-doped Zn(O,S) had the best properties and it could totally reduce 4-NP after 2h photoreactions under low UV illumination. The hydrogen ion was proposed to involve the 4-NP reduction to 4-AP, which is hydrogen ion and electron replaced the oxygen in amino (NO2) group of 4-NP to form the nitro (NH2) group. We alsoproposed the incorporation of Mn in Zn site in the Zn(O,S) host lattice could make the oxygen surface bonding weak for easily forming the oxygen vacancy. The more oxygen vacancy for more hydrogen ion would be generated to consume for 4-NP reduction.

Electrodeposited Cu2ZnSnS4 thin films

CSIR Research Space (South Africa)

Valdes, M

2014-05-01

Full Text Available Cu(sub2)ZnSnS(sub4)(CZTS) thin films have been prepared using Electrochemical Atomic Layer Deposition (EC-ALD)and also by one-step conventional constant potential electrodeposition. Optimal deposition conditionswere investigated using cyclic...

Metastasis-inducing S100A4 and RANTES cooperate in promoting tumor progression in mice.

Directory of Open Access Journals (Sweden)

Birgitte Forst

2010-04-01

Full Text Available The tumor microenvironment has been described as a critical milieu determining tumor growth and metastases. A pivotal role of metastasis-inducing S100A4 in the development of tumor stroma has been proven in animal models and verified in human breast cancer biopsies. Expression and release of S100A4 has been shown in various types of stroma composing cells, including fibroblasts and immune cells. However, the events implicated in upstream and downstream pathways regulating the activity of the extracellular S100A4 protein in the tumor milieu remain unsolved.We studied the interplay between the tumor cell-derived cytokine regulated-upon-activation, normal T-cell expressed and secreted (RANTES; CCL5 and S100A4 which were shown to be critical factors in tumor progression. We found that RANTES stimulates the externalization of S100A4 via microparticle shedding from the plasma membrane of tumor and stroma cells. Conversely, the released S100A4 protein induces the upregulation of fibronectin (FN in fibroblasts and a number of cytokines, including RANTES in tumor cells as well as stimulates cell motility in a wound healing assay. Importantly, using wild type and S100A4-deficient mouse models, we demonstrated a substantial influence of tumor cell-derived RANTES on S100A4 release into blood circulation which ultimately increases the metastatic burden in mice.Altogether, the data presented strongly validate the pro-metastatic function of S100A4 in the tumor microenvironment and define how the tumor cell-derived cytokine RANTES acts as a critical regulator of S100A4-dependent tumor cell dissemination. Additionally, for the first time we demonstrated the mechanism of S100A4 release associated with plasma membrane microparticle shedding from various cells types.

Hadronic Transitions from Upsilon (2S) to Upsilon (1s) and Upsilon Dipion Transitions at Energies Near the Upsilon (4S)

Science.gov (United States)

Kotoy, Sergei Anatolievich

This dissertation consists of two closely related analyses, both of which were performed using data collected with the CLEO II detector at the Cornell Electron Storage Ring. In the first analysis, using the world largest data sample of Υ(2 S) events, we have investigated the hadronic transitions between the Υ(2S) and the Υ(1S), i.e. decays of the Υ(2S) into the Υ(1S), plus a pair of pions ( p+p- or p0p0 ), a single η or a single p0 . The dipion transitions U(2S)-->U( 1S)pp were studied most closely, by using two different techniques: ``exclusive'' and ``inclusive''. In these measurements we determine the U(2S)-->U( 1S)pp branching ratios, and, by combining the exclusive and inclusive results, we derive the Υ(1S), leptonic branching ratios Bee and Bmm . Parameters of the ππ system in the dipion transitions (dipion invariant mass spectra, angular distributions) were analyzed and found to be consistent with current theoretical models. Lastly, we searched for the η and single π0 transitions and obtained upper limits on the branching ratios B(U(2S) -->U(1S)h ) and B(U(2S) -->U(1S)p 0) . In the second analysis, the data collected at the center of mass energies near the Υ(4S) were used to search for the dipion transition between pairs of Υ resonances. As a result of this search, we established upper limits on the branching ratios of the dipion transitions post='par'>p+p- and U(4S)-->U( 1S)p+p- , and measured the cross-sections for the radiative production of Υ(3 S) and Υ(2S) resonances e+e--->U(nS) g at the center of mass energies of Ecm = 10.58 GeV and Ecm = 10.52 GeV.

Currents of thermally stimulated depolarization in CaIn2S4 single crystals

International Nuclear Information System (INIS)

Tagiev, B.G.; Tagiev, O.B.; Dzhabbarov, R.B.; Musaeva, N.N.

1996-01-01

The results of investigation into currents of thermally stimulated depolarization in CaIn 2 S 4 monocrystals are presented for the first time. Spectra of thermally stimulated depolarization for In-CaIn S4 -In structures are measured under T=99 K at various rates of heat, times of polarization and times of expectation following switching off of electrical field up to beginning of measurements of shorting. The main parameters of capture cross section, partial factor, concentration of traps, are determined. It is determined that one may observed a biomolecular mechanism with a strong secondary capture in CaIn 2 S 4 monocrystals. 9 refs.; 4 figs

40 CFR 180.1281 - S-Abscisic Acid, (S)-5-(1-hydroxy-2,6,6-trimethyl-4-oxo-1-cyclohex-2-enyl)-3-methyl-penta-(2Z,4E...

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 23 2010-07-01 2010-07-01 false S-Abscisic Acid, (S)-5-(1-hydroxy-2,6... Exemptions From Tolerances § 180.1281 S-Abscisic Acid, (S)-5-(1-hydroxy-2,6,6-trimethyl-4-oxo-1-cyclohex-2... from the requirement of a tolerance is established for residues of S-Abscisic Acid in or on all food...

Reduced graphene oxide-CdS nanocomposite with enhanced photocatalytic 4-Nitrophenol degradation

Science.gov (United States)

Chakraborty, Koushik; Ibrahim, Sk; Das, Poulomi; Ghosh, Surajit; Pal, Tanusri

2017-05-01

We report the photocatalytic activity of reduced graphene oxide cadmium sulfide (RGO-CdS) composite towards the degradation of 4-Nitrophenol (4-NP) under simulated solar light illumination. The solution processable RGO-CdS composite was synthesized by one pot single step low cost solvothermal process, where the reduction of graphene oxide (GO), synthesis and attachment of CdS onto RGO sheets were done simultaneously. The structural and morphological characterization of the RGO-CdS composite and the reduction of GO was confirmed by X-ray diffractometry, TEM imaging and Fourier transform infrared spectroscopy respectively. The photocatalytic efficiency of RGO-CdS composite is 2.6 times higher in compare to controlled CdS. In RGO-CdS composite the photo induced electrons transfer from CdS nanorod to RGO sheets, which reduces the recombination probability of photo generated electron-hole in the CdS. These well separated photoinduced charges enhanced the photocatalytic activity of the RGO-CdS composite. Our study establishes the RGO-CdS composite as a potential photocatalyst for the degradation of organic water pollutant.

Enthalpy-increment measurements for CsI(s) and Cs2CrO4(s) by high-temperature Calvet calorimetry

International Nuclear Information System (INIS)

Venugopal, V.; Agarwal, R.; Roy, K.N.; Prasad, R.; Sood, D.D.

1987-01-01

Molar thermodynamic properties of CsI(s) and Cs 2 Cr O 4 (s) have been evaluated by enthalpy-increment measurements, using a Calvet high-temperature calorimeter. Least squares analyses were performed on the enthalpy increment results. Data is presented in tabular form for the dependence of enthalpy increments on temperature, in the range 333 to 822 K, for both caesium compounds, along with the thermal properties of the compounds. Good agreement is found between the present data and previously reported results on reduced enthalpy increments of CsI(s) and Cs 2 CrO 4 (s). (U.K.)

Functional significance of metastasis-inducing S100A4(Mts1) in tumor-stroma interplay

DEFF Research Database (Denmark)

Schmidt-Hansen, Birgitte; Klingelhöfer, Jörg; Grum-Schwensen, Birgitte

2004-01-01

Causal implication of S100A4 in inducing metastases was convincingly shown previously. However, the mechanisms that associate S100A4 with tumor progression are not well understood. S100A4 protein, as a typical member of the S100 family, exhibits dual, intracellular and extracellular, functions. T...

Unitary Supermultiplets of $OSp(8^{*}|4)$ and the $AdS_{7}/CFT_{6}$ Duality

CERN Document Server

Günaydin, M; Gunaydin, Murat; Takemae, Seiji

2000-01-01

We study the unitary supermultiplets of the N=4 d=7 anti-de Sitter (AdS_7) superalgebra OSp(8^*|4), with the even subalgebra SO(6,2) X USp(4), which is the symmetry superalgebra of M-theory on AdS_7 X S^4. We give a complete classification of the positive energy doubleton and massless supermultiplets of OSp(8^*|4) . The ultra-short doubleton supermultiplets do not have a Poincaré limit in AdS_7 and correspond to superconformal field theories on the boundary of AdS_7 which can be identified with d=6 Minkowski space. We show that the six dimensional Poincare mass operator vanishes identically for the doubleton representations. By going from the compact U(4) basis of SO^*(8)=SO(6,2) to the noncompact basis SU^*(4)XD (d=6 Lorentz group times dilatations) one can associate the positive (conformal) energy representations of SO^*(8) with conformal fields transforming covariantly under the Lorentz group in d=6. The oscillator method used for the construction of the unitary supermultiplets of OSp(8^*|4) can be given ...

Pr4N2S3 and Pr4N2Se3: two non-isostructural praseodymium(iii) nitride chalcogenides

International Nuclear Information System (INIS)

Lissner, Falk; Schleid, Thomas

2005-01-01

The non-isostructural nitride chalcogenides of praseodymium, Pr 4 N 2 S 3 and Pr 4 N 2 Se 3 , are formed by the reaction of the praseodymium metal with sodium azide (NaN 3 ), praseodymium trihalide (PrX 3 ; X = Cl, Br, I) and the respective chalcogen (sulfur or selenium) at 900 C in evacuated silica ampoules after seven days. Both crystallize monoclinically in space group C2/c (Pr 4 N 2 S 3 : a = 1788.57(9), b = 986.04(5), c = 1266.49(6) pm, β = 134.546(7) , Z = 8; Pr 4 N 2 Se 3 : a = 1311.76(7), b = 1017.03(5), c = 650.42(3) pm, β = 90.114(6) , Z = 4). The crystal structures of both compounds show a layered construction, dominated by N 3- -centred (Pr 3+ ) 4 tetrahedra which share a common edge first. Continuing linkage of the so resulting bitetrahedral [N 2 Pr 6 ] 12+ units via the non-connected vertices to layers according to [stack ∞ 2 ]{[N(Pr) 2/2 e (Pr') 2/2 v ] 3+ } forms different kinds of tetrahedral nets which can be described as layers consisting of ''four- and eight-rings'' for Pr 4 N 2 S 3 and as layers of ''six-rings'' for Pr 4 N 2 Se 3 . Whereas the crystal structure of Pr 4 N 2 S 3 exhibits four different Pr 3+ cations with coordination numbers of six (2 x) and seven (2 x) against N 3- and S 2- , the number of cations in the nitride selenide (Pr 4 N 2 Se 3 ) is reduced to half (Pr1 and Pr2) also having six- and sevenfold anionic coordination spheres. Further motifs for the connection of [NM 4 ] 9+ tetrahedra in crystal structures of nitride chalcogenides and halides of the rare-earth elements with ratios of N: M = 1: 2 are presented and discussed. (Abstract Copyright [2005], Wiley Periodicals, Inc.) [de

Properties of pulsed electrodeposited CdIn2S4 thin film

International Nuclear Information System (INIS)

Hankare, P.P.; Kokate, A.V.; Asabe, M.R.; Delekar, S.D.; Chougule, B.K.

2006-01-01

CdIn 2 S 4 thin films are prepared by pulsed electrodeposition technique over F:SnO 2 glass and stainless steel substrates in galvanostatic mode from an aqueous acidic bath containing CdSO 4 , InCl 3 and Na 2 S 2 O 3 . The growth kinetics of the film was studied and the deposition parameters such as electrolyte bath concentration, bath temperature, time of deposition, deposition current, and pH of the electrolyte bath are optimized. X-ray diffraction (XRD) analysis of the as deposited and annealed films showed the presence of polycrystalline nature. Energy dispersive analysis (EDAX) spectrum of the surface composition confirms the nearly stoichiometric CdIn 2 S 4 nature of the film. Surface morphology studies by scanning electron microscope (SEM) shows that, the deposited films are well adherent and grains are uniformly distributed over the surface of substrate. The optical transmission spectra show a direct band gap value of 2.16 eV

4-(4,4-Difluoro-1,3,5,7-tetramethyl-3a-aza-4a-azonia-4-borata-s-indacen-8-ylbenzonitrile

Directory of Open Access Journals (Sweden)

Yuting Chen

2011-04-01

Full Text Available The title compound, C20H18BF2N3, contains one C9BN2 (Bodipy framework and one cyanobenzyl group. The Bodipy framework is essentially planar with a maximum deviation of 0.041 (2 Å. The introduction of two methyl groups at positions 1 and 7 of s-indacene in the Bodipy unit results in almost orthogonal configuration between the mean plane of the Bodipy unit and the cyanobenzyl group [dihedral angle = 89.78 (4°].

S4HARA: System for HIV/AIDS resource allocation.

Science.gov (United States)

Lasry, Arielle; Carter, Michael W; Zaric, Gregory S

2008-03-26

HIV/AIDS resource allocation decisions are influenced by political, social, ethical and other factors that are difficult to quantify. Consequently, quantitative models of HIV/AIDS resource allocation have had limited impact on actual spending decisions. We propose a decision-support System for HIV/AIDS Resource Allocation (S4HARA) that takes into consideration both principles of efficient resource allocation and the role of non-quantifiable influences on the decision-making process for resource allocation. S4HARA is a four-step spreadsheet-based model. The first step serves to identify the factors currently influencing HIV/AIDS allocation decisions. The second step consists of prioritizing HIV/AIDS interventions. The third step involves allocating the budget to the HIV/AIDS interventions using a rational approach. Decision-makers can select from several rational models of resource allocation depending on availability of data and level of complexity. The last step combines the results of the first and third steps to highlight the influencing factors that act as barriers or facilitators to the results suggested by the rational resource allocation approach. Actionable recommendations are then made to improve the allocation. We illustrate S4HARA in the context of a primary healthcare clinic in South Africa. The clinic offers six types of HIV/AIDS interventions and spends US$750,000 annually on these programs. Current allocation decisions are influenced by donors, NGOs and the government as well as by ethical and religious factors. Without additional funding, an optimal allocation of the total budget suggests that the portion allotted to condom distribution be increased from 1% to 15% and the portion allotted to prevention and treatment of opportunistic infections be increased from 43% to 71%, while allocation to other interventions should decrease. Condom uptake at the clinic should be increased by changing the condom distribution policy from a pull system to a push

Static elliptic minimal surfaces in AdS{sub 4}

Energy Technology Data Exchange (ETDEWEB)

Pastras, Georgios [NCSR ' ' Demokritos' ' , Institute of Nuclear and Particle Physics, Attiki (Greece)

2017-11-15

The Ryu-Takayanagi conjecture connects the entanglement entropy in the boundary CFT to the area of open co-dimension two minimal surfaces in the bulk. Especially in AdS{sub 4}, the latter are two-dimensional surfaces, and, thus, solutions of a Euclidean non-linear sigma model on a symmetric target space that can be reduced to an integrable system via Pohlmeyer reduction. In this work, we construct static minimal surfaces in AdS{sub 4} that correspond to elliptic solutions of the reduced system, namely the cosh-Gordon equation, via the inversion of Pohlmeyer reduction. The constructed minimal surfaces comprise a two-parameter family of surfaces that include helicoids and catenoids in H{sup 3} as special limits. Minimal surfaces that correspond to identical boundary conditions are discovered within the constructed family of surfaces and the relevant geometric phase transitions are studied. (orig.)

Search for the Y via e(+)e(-) -> gamma phi J/psi at root s=4.23, 4.26 and 4.36 GeV

NARCIS (Netherlands)

Ablikim, M.; Achasov, M. N.; Ai, X. C.; Albayrak, O.; Albrecht, M.; Ambrose, D. J.; Amoroso, A.; An, F. F.; An, Q.; Bai, J. Z.; Ferroli, R. Baldini; Ban, Y.; Bennett, D. W.; Bennett, J. V.; Bertani, M.; Bettoni, D.; Bian, J. M.; Bianchi, F.; Boger, E.; Bondarenko, O.; Boyko, I.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, H. Y.; Chen, J. C.; Chen, M. L.; Chen, S. J.; Chen, X.; Chen, X. R.; Chen, Y. B.; Cheng, H. P.; Chu, X. K.; Cibinetto, G.; Cronin-Hennessy, D.; Dai, H. L.; Dai, J. P.; Dbeyssi, A.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; De Mori, F.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Du, S. X.; Duan, P. F.; Fan, J. Z.; Fang, J.; Fang, S. S.; Fang, X.; Fang, Y.; Fava, L.; Feldbauer, F.; Felici, G.; Feng, C. Q.; Fioravanti, E.; Fritsch, M.; Fu, C. D.; Gao, Q.; Gao, Y.; Garzia, I.; Goetzen, K.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, Y. T.; Guan, Y. H.; Guo, A. Q.; Guo, L. B.; Guo, T.; Guo, Y.; Guo, Y. P.; Haddadi, Z.; Hafner, A.; Han, S.; Han, Y. L.; Harris, F. A.; He, K. L.; He, Z. Y.; Held, T.; Heng, Y. K.; Hou, Z. L.; Hu, C.; Hu, H. M.; Hu, J. F.; Hu, T.; Hu, Y.; Huang, G. M.; Huang, G. S.; Huang, H. P.; Huang, J. S.; Huang, X. T.; Huang, Y.; Hussain, T.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, L. L.; Jiang, L. W.; Jiang, X. S.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Johansson, T.; Julin, A.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; Ke, B. C.; Kliemt, R.; Kloss, B.; Kolcu, O. B.; Kopf, B.; Kornicer, M.; Kuehn, W.; Kupsc, A.; Lai, W.; Lange, J. S.; Lara, M.; Larin, P.; Li, C. H.; Li, Cheng; Li, D. M.; Li, F.; Li, G.; Li, H. B.; Li, J. C.; Li, Jin; Li, K.; Li, K.; Li, P. R.; Li, T.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. M.; Li, X. N.; Li, X. Q.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; Lin, D. X.; Liu, B. J.; Liu, C. L.; Liu, C. X.; Liu, F. H.; Liu, Fang; Liu, Feng; Liu, H. B.; Liu, H. H.; Liu, H. H.; Liu, H. M.; Liu, J.; Liu, J. P.; Liu, J. Y.; Liu, K.; Liu, K. Y.; Liu, L. D.; Liu, P. L.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, X. X.; Liu, Y. B.; Liu, Z. A.; Liu, Zhiqiang; Liu, Zhiqing; Loehner, H.; Lou, X. C.; Lu, H. J.; Lu, J. G.; Lu, R. Q.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, T.; Luo, X. L.; Lv, M.; Lyu, X. R.; Ma, F. C.; Ma, H. L.; Ma, L. L.; Ma, Q. M.; Ma, S.; Ma, T.; Ma, X. N.; Ma, X. Y.; Maas, F. E.; Maggiora, M.; Malik, Q. A.; Mao, Y. J.; Mao, Z. P.; Marcello, S.; Messchendorp, J. G.; Min, J.; Min, T. J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Morales, C. Morales; Moriya, K.; Muchnoi, N. Yu.; Muramatsu, H.; Nefedov, Y.; Nerling, F.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Patteri, P.; Pelizaeus, M.; Peng, H. P.; Peters, K.; Ping, J. L.; Ping, R. G.; Poling, R.; Pu, Y. N.; Qi, M.; Qian, S.; Qiao, C. F.; Qin, L. Q.; Qin, N.; Qin, X. S.; Qin, Y.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Ren, H. L.; Ripka, M.; Rong, G.; Ruan, X. D.; Santoro, V.; Sarantsev, A.; Savrie, M.; Schoenning, K.; Schumann, S.; Shan, W.; Shao, M.; Shen, C. P.; Shen, P. X.; Shen, X. Y.; Sheng, H. Y.; Shepherd, M. R.; Song, W. M.; Song, X. Y.; Sosio, S.; Spataro, S.; Spruck, B.; Sun, G. X.; Sun, J. F.; Sun, S. S.; Sun, Y. J.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tang, C. J.; Tang, X.; Tapan, I.; Thorndike, E. H.; Tiemens, M.; Toth, D.; Ullrich, M.; Uman, I.; Varner, G. S.; Wang, B.; Wang, B. L.; Wang, D.; Wang, D. Y.; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, P.; Wang, P. L.; Wang, Q. J.; Wang, S. G.; Wang, W.; Wang, X. F.; Wang, Y. D.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. H.; Wang, Z. Y.; Weber, T.; Wei, D. H.; Wei, J. B.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, Z.; Xia, L. G.; Xia, Y.; Xiao, D.; Xiao, Z. J.; Xie, Y. G.; Xu, G. F.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Yan, L.; Yan, W. B.; Yan, W. C.; Yan, Y. H.; Yang, H. X.; Yang, L.; Yang, Y.; Yang, Y. X.; Ye, H.; Ye, M.; Ye, M. H.; Yin, J. H.; Yu, B. X.; Yu, C. X.; Yu, H. W.; Yu, J. S.; Yuan, C. Z.; Yuan, W. L.; Yuan, Y.; Yuncu, A.; Zafar, A. A.; Zallo, A.; Zeng, Y.; Zhang, B. X.; Zhang, B. Y.; Zhang, C.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J. J.; Zhang, J. L.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, K.; Zhang, L.; Zhang, S. H.; Zhang, X. J.; Zhang, X. Y.; Zhang, Y.; Zhang, Y. H.; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, J. Y.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, Q. W.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, W. J.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, Li; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhu, K.; Zhu, K. J.; Zhu, S.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zou, B. S.; Zou, J. H.

2015-01-01

Using data samples collected at center-of-mass energies root s = 4.23, 4.26, and 4.36 GeV with the BESIII detector operating at the BEPCII storage ring, we search for the production of the charmoniumlike state Y(4140) through a radiative transition followed by its decay to phi J/psi. No significant

Sensitization of interferon-γ induced apoptosis in human osteosarcoma cells by extracellular S100A4

International Nuclear Information System (INIS)

Pedersen, Kjetil Boye; Andersen, Kristin; Fodstad, Øystein; Mælandsmo, Gunhild Mari

2004-01-01

S100A4 is a small Ca 2+ -binding protein of the S100 family with metastasis-promoting properties. Recently, secreted S100A4 protein has been shown to possess a number of functions, including induction of angiogenesis, stimulation of cell motility and neurite extension. Cell cultures from two human osteosarcoma cell lines, OHS and its anti-S100A4 ribozyme transfected counterpart II-11b, was treated with IFN-γ and recombinant S100A4 in order to study the sensitizing effects of extracellular S100A4 on IFN-γ mediated apoptosis. Induction of apoptosis was demonstrated by DNA fragmentation, cleavage of poly (ADP-ribose) polymerase and Lamin B. In the present work, we found that the S100A4-expressing human osteosarcoma cell line OHS was more sensitive to IFN-γ-mediated apoptosis than the II-11b cells. S100A4 protein was detected in conditioned medium from OHS cells, but not from II-11b cells, and addition of recombinant S100A4 to the cell medium sensitized II-11b cells to apoptosis induced by IFN-γ. The S100A4/IFN-γ-mediated induction of apoptosis was shown to be independent of caspase activation, but dependent on the formation of reactive oxygen species. Furthermore, addition of extracellular S100A4 was demonstrated to activate nuclear factor-κB (NF-κB). In conclusion, we have shown that S100A4 sensitizes osteosarcoma cells to IFN-γ-mediated induction of apoptosis. Additionally, extracellular S100A4 activates NF-κB, but whether these events are causally related remains unknown

Babes and boobs? analysis of JAMA cover art.

Science.gov (United States)

Clark, J P

To determine the representation of the sexes in JAMA cover art. Review of 50 consecutive issues. JAMA, March 1997-March 1998. Numbers and nature of covers portraying men and women. Of the 50 covers, 34 depicted humans. 15 depicted women, 13 men, and 6 were of mixed or indeterminate sex. 11 pictures of women included a child and five included nudity. One cover showed a man with a child (not as a father) and none depicted nudity. Men were depicted exclusively in authoritative roles. Much of the cover art gives strong messages about sexual stereotypes that are inappropriate in modern society. JAMA should consider reviewing its policy for choosing cover art.

Structural and elemental characterization of high efficiency Cu2ZnSnS4 solar cells

Science.gov (United States)

Wang, Kejia; Shin, Byungha; Reuter, Kathleen B.; Todorov, Teodor; Mitzi, David B.; Guha, Supratik

2011-01-01

We have carried out detailed microstructural studies of phase separation and grain boundary composition in Cu2ZnSnS4 based solar cells. The absorber layer was fabricated by thermal evaporation followed by post high temperature annealing on hot plate. We show that inter-reactions between the bottom molybdenum and the Cu2ZnSnS4, besides triggering the formation of interfacial MoSx, results in the out-diffusion of Cu from the Cu2ZnSnS4 layer. Phase separation of Cu2ZnSnS4 into ZnS and a Cu-Sn-S compound is observed at the molybdenum-Cu2ZnSnS4 interface, perhaps as a result of the compositional out-diffusion. Additionally, grain boundaries within the thermally evaporated absorber layer are found to be either Cu-rich or at the expected bulk composition. Such interfacial compound formation and grain boundary chemistry likely contributes to the lower than expected open circuit voltages observed for the Cu2ZnSnS4 devices.

Interaction between resonances through autoionization continua near the 4s-threshold in KrII

International Nuclear Information System (INIS)

Demekhin, Ph V; Petrov, I D; Lagutin, B M; Sukhorukov, V L; Vollweiler, F; Klumpp, S; Ehresmann, A; Schartner, K-H; Schmoranzer, H

2005-01-01

The interaction between resonances through autoionization continua and the interaction between autoionization continua were investigated theoretically and experimentally for the photoionization process of the 4p- and 4s-shells and for the population of 4p 4 ( 3 P)5s 4 P J , 4p 4 ( 3 P)5s 2 P J and 4p 4 ( 3 P)4d 4 D J satellites of KrII. Cross sections for the satellite production and the angular distribution parameter of the fluorescence radiation were measured by photon-induced fluorescence spectroscopy after excitationx with linearly polarized monochromatized synchrotron radiation at exciting-photon energies between 28.45 eV and 29.95 eV with an exciting-photon energy resolution of 10 meV (FWHM). Measured cross sections are in good agreement with the computed ones. A refined assignment of resonances in the proximity of the 4s 1 4p 6 5p resonance was performed. It was concluded that there is a strong influence of the core rearrangement, of the interaction between resonances through the autoionization continua and of the interaction between autoionization continua, on the investigated processes on the basis of the observed good overall agreement between the computed and measured quantities

Recreatief/toeristisch onderzoek in Wageningen: organisatie en perspectief.

NARCIS (Netherlands)

Dietvorst, A.G.J.

1989-01-01

Themagedeelte waarin o.a. aandacht voor: toeristisch-recreatief onderwijs in Wageningen; het belang van een analyse van de samenhang in de recreatief-toeristische infrastructuur voor het beleid t.a.v. recreatie in het landelijk gebied; methoden voor herwegen van gestratificeerde steekproeven t.b.v.

Transport en afbraak van olie in bodem en grondwater

NARCIS (Netherlands)

Begeman, E.; Gestel, van C.A.M.

1978-01-01

De bestrijding van olieverontreiniging in de bodem is vooral voor dezedrinkwaterbedrijven erg belangrijk. Het verkrijgen van inzicht in het transport van olie in de bodem is van belang om de verspreiding van een eventuele vervuiling te kunnen voorspellen, zodat de bestrijding effectiever kan worden

Cow health: bacteriological diagnostic examination

NARCIS (Netherlands)

Smith, H.E.; Sampimon, O.C.; Lam, T.J.G.M.

2007-01-01

Mastitis wordt vrijwel altijd veroorzaakt door een infectie met bacteriële ziektekiemen. Virale infecties kunnen ook een rol spelen, maar zijn van ondergeschikt belang. Dit artikel zal daarom alleen ingaan op diagnostisch onderzoek van bacteriele ziektekiemen. Er zijn veel verschillende bacteriën

Database opzet in het verkeer

NARCIS (Netherlands)

van Dijk, Alwin

2018-01-01

De ‘Database opzet in het verkeer’ geeft een overzicht van rechtspraak waarin opzetdelicten als doodslag, (zware) mishandeling of bedreiging zijn ten laste gelegd in verkeerszaken. De database is van belang voor de rechtspraak, het Openbaar Ministerie, de advocatuur en de wetenschap. De in de

Ziek en Zeer : Monitoring dwergcicaden in hyacintenveld

NARCIS (Netherlands)

Vink, P.

2012-01-01

Vanaf 2007 zien we jaarlijks problemen in de broeierij met zogenoemde 'Lissers' in hyacinten, veroorzaakt door een besmetting met fytoplasma's. Deze ziekteverwekker wordt tijdens de bollenteelt overgebracht door (dwerg)cicaden. Van belang leek het om na te gaan hoe vroeg in het seizoen deze insecten

Verandering van binnenuit : dynamiek en werkgelegenheid

NARCIS (Netherlands)

Speldekamp, Daniel

2014-01-01

De mate waarin een economie welvaart creëert hangt samen met haar werkgelegenheidscreatie, regionaal product en productiviteit. De komende jaren is het van belang dat de crisiswerkloosheid teruggedrongen wordt. Er lijkt tevens een overgang gaande naar een kennis ofwel creatieve economie. Hierdoor is

Opposite effects of the S4-S5 linker and PIP2 on voltage-gated channel function: KCNQ1/KCNE1 and other channels

Directory of Open Access Journals (Sweden)

Frank S Choveau

2012-07-01

Full Text Available Voltage-gated potassium (Kv channels are tetramers, each subunit presenting six transmembrane segments (S1-S6, with each S1-S4 segments forming a voltage-sensing domain (VSD and the four S5-S6 forming both the conduction pathway and its gate. S4 segments control the opening of the intracellular activation gate in response to changes in membrane potential. Crystal structures of several voltage-gated ion channels in combination with biophysical and mutagenesis studies highlighted the critical role of the S4-S5 linker (S4S5L and of the S6 C-terminal part (S6T in the coupling between the VSD and the activation gate. Several mechanisms have been proposed to describe the coupling at a molecular scale. This review summarizes the mechanisms suggested for various voltage-gated ion channels, including a mechanism that we described for KCNQ1, in which S4S5L is acting like a ligand binding to S6T to stabilize the channel in a closed state. As discussed in this review, this mechanism may explain the reverse response to depolarization in HCN-like channels. As opposed to S4S5L, the phosphoinositide, phosphatidylinositol 4,5-bisphosphate (PIP2, stabilizes KCNQ1 channel in an open state. Many other ion channels (not only voltage-gated require PIP2 to function properly, confirming its crucial importance as an ion channel co-factor. This is highlighted in cases in which an altered regulation of ion channels by PIP2 leads to channelopathies, as observed for KCNQ1. This review summarizes the state of the art on the two regulatory mechanisms that are critical for KCNQ1 and other voltage-gated channels function (PIP2 and S4-S5L, and assesses their potential physiological and pathophysiological roles.

Bulk Extractor 1.4 User’s Manual

Science.gov (United States)

2013-08-01

optimistically decompresses data in ZIP, GZIP, RAR, and Mi- crosoft’s Hibernation files. This has proven useful, for example, in recovering email...command line. Java 7 or above must be installed on the machine for the Bulk Extractor Viewer to run. Instructions on running bulk_extractor from the... Hibernation File Fragments (decompressed and processed, not carved) Subsection 4.6 winprefetch Windows Prefetch files, file fragments (processed

Protonation/reduction dynamics at the [4Fe-4S] cluster of the hydrogen-forming cofactor in [FeFe]-hydrogenases.

Science.gov (United States)

Senger, Moritz; Mebs, Stefan; Duan, Jifu; Shulenina, Olga; Laun, Konstantin; Kertess, Leonie; Wittkamp, Florian; Apfel, Ulf-Peter; Happe, Thomas; Winkler, Martin; Haumann, Michael; Stripp, Sven T

2018-01-31

The [FeFe]-hydrogenases of bacteria and algae are the most efficient hydrogen conversion catalysts in nature. Their active-site cofactor (H-cluster) comprises a [4Fe-4S] cluster linked to a unique diiron site that binds three carbon monoxide (CO) and two cyanide (CN - ) ligands. Understanding microbial hydrogen conversion requires elucidation of the interplay of proton and electron transfer events at the H-cluster. We performed real-time spectroscopy on [FeFe]-hydrogenase protein films under controlled variation of atmospheric gas composition, sample pH, and reductant concentration. Attenuated total reflection Fourier-transform infrared spectroscopy was used to monitor shifts of the CO/CN - vibrational bands in response to redox and protonation changes. Three different [FeFe]-hydrogenases and several protein and cofactor variants were compared, including element and isotopic exchange studies. A protonated equivalent (HoxH) of the oxidized state (Hox) was found, which preferentially accumulated at acidic pH and under reducing conditions. We show that the one-electron reduced state Hred' represents an intrinsically protonated species. Interestingly, the formation of HoxH and Hred' was independent of the established proton pathway to the diiron site. Quantum chemical calculations of the respective CO/CN - infrared band patterns favored a cysteine ligand of the [4Fe-4S] cluster as the protonation site in HoxH and Hred'. We propose that proton-coupled electron transfer facilitates reduction of the [4Fe-4S] cluster and prevents premature formation of a hydride at the catalytic diiron site. Our findings imply that protonation events both at the [4Fe-4S] cluster and at the diiron site of the H-cluster are important in the hydrogen conversion reaction of [FeFe]-hydrogenases.

Resonant photoelectron spectroscopy at the Mo 4p→4d absorption edge in MoS2

International Nuclear Information System (INIS)

Lince, J.R.; Didziulis, S.V.; Yarmoff, J.A.

1991-01-01

A systematic study has been conducted of the resonant behavior of the valence-band photoelectron spectrum of MoS 2 for hν=26--70 eV, spanning the Mo 4p→4d transition region. A broad Fano-like resonance appears at ∼42 eV in the constant-initial-state (CIS) intensity plot of the d z 2 peak near the valence-band maximum [∼2 eV binding energy (BE)], confirming its predominantly Mo 4d character. A second shoulder on the higher-hν side of the maximum in the d z 2 CIS intensity plot is suggested to result from transitions to unoccupied states in the 5sp band ∼10 eV above E F , by comparison with a partial-yield spectrum and previous inverse-photoemission data. The region of the valence band in the range 3--4.5-eV BE also exhibits resonant behavior, indicating Mo 4d character, although somewhat less than for the d z 2 peak. The 5--7-eV BE range does not exhibit resonance behavior at the Mo 4p edge and, therefore, contains negligible Mo 4d character. A feature at ∼30 eV in the CIS intensity plot for the 5--7-eV BE range could not be definitively assigned in this study, but may be due to a resonance between direct photoemission and a process involving absorption and autoionization of electronic states that contain Mo 5s and 5p character

Hyperfine structure in 5s4d 3D-5snf transitions of 87Sr

International Nuclear Information System (INIS)

Bushaw, B.A.; Kluge, H.J.; Lantzsch, J.; Schwalbach, R.; Stenner, J.; Stevens, H.; Wendt, K.; Zimmer, K.

1993-01-01

The hyperfine spectra of the 5s4d 3 D 1 -5s20f, 5s4d 3 D 2 -5s23f, and 5s4d 3 D 3 -5s32f transitions of 87 Sr (I=9/2) have been measured by collinear fast beam laser spectroscopy. The structure in the upper configurations is highly perturbed by fine structure splitting that is of comparable size to the hyperfine interaction energy. These perturbations can be adequately treated with conventional matrix diagonalization methods, using the 5s-electron magnetic dipole interaction term a 5s and the unperturbed fine structure splittings as input parameters. Additionally, hyperfine constants for the lower 5s4d 3 D configurations, including the A- and B-factors and a separation of the individual s- and d-electron contributions to these factors, are derived. (orig.)

Black hole microstates in AdS{sub 4} from supersymmetric localization

Energy Technology Data Exchange (ETDEWEB)

Benini, Francesco [Blackett Laboratory, Imperial College London,South Kensington Campus, London SW7 2AZ (United Kingdom); International School for Advanced Studies (SISSA),via Bonomea 265, 34136 Trieste (Italy); Hristov, Kiril [Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences,Tsarigradsko Chaussee 72, 1784 Sofia (Bulgaria); Zaffaroni, Alberto [Dipartimento di Fisica, Università di Milano-Bicocca,piazza della Scienza 3, I-20126 Milano (Italy); INFN, sezione di Milano-Bicocca,piazza della Scienza 3, I-20126 Milano (Italy)

2016-05-10

This paper addresses a long standing problem, the counting of the microstates of supersymmetric asymptotically AdS black holes in terms of a holographically dual field theory. We focus on a class of asymptotically AdS{sub 4} static black holes preserving two real supercharges which are dual to a topologically twisted deformation of the ABJM theory. We evaluate in the large N limit the topologically twisted index of the ABJM theory and we show that it correctly reproduces the entropy of the AdS{sub 4} black holes. An extremization of the index with respect to a set of chemical potentials is required. We interpret it as the selection of the exact R-symmetry of the superconformal quantum mechanics describing the horizon of the black hole.

Rational design and enantioselective synthesis of (1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarboxylic acid - a novel inhibitor at human glutamate transporter subtypes 1, 2, and 3

DEFF Research Database (Denmark)

Bunch, Lennart; Nielsen, Birgitte; Jensen, Anders A.

2006-01-01

The natural product kainic acid is used as template for the rational design of a novel conformationally restricted (S)-glutamic acid (Glu) analogue, (1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarboxylic acid (1a). The target structure 1a was synthesized from commercially available (S)-pyroglut......The natural product kainic acid is used as template for the rational design of a novel conformationally restricted (S)-glutamic acid (Glu) analogue, (1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarboxylic acid (1a). The target structure 1a was synthesized from commercially available (S...

CERN’s Linac4 H− sources: Status and operational results

International Nuclear Information System (INIS)

Lettry, J.; Aguglia, D.; Andersson, P.; Bertolo, S.; Butterworth, A.; Coutron, Y.; Dallocchio, A.; David, N.; Chaudet, E.; Fink, D.; Gil-Flores, J.; Garlasche, M.; Grudiev, A.; Guida, R.; Hansen, J.; Haase, M.; Jones, A.; Koszar, I.; Machado, C.; Mastrostefano, C.

2015-01-01

Two volume sources equipped with DESY and CERN plasma generators and a low voltage electron dump were operated at 45 kV in the Linac4 tunnel and on a dedicated test stand. These volume sources delivered approximately 20 mA and ensured the commissioning of the Radio Frequency Quadrupole accelerator and of the first section of the Drift Tube Linac. CERN’s prototype of a cesiated surface source equipped with this electron dump was operated continuously from November 2013 to April 2014 on the ion source test stand and is being commissioned in the Linac4 tunnel. Before cesiation, the prototype conditioned in volume mode provided up to 30 mA H − beam. Short cesiations, of the order of 10 mg effectively reduced the intensity of co-extracted electrons down to 2 - 8 times the H − current; this cesiated surface operation mode delivered up to 60 mA H − beam. An H − beam of the order of 40 mA was sustained up to four weeks operation with 500 μs pulses at 1.2s spacing. A new extraction was designed to match these beam properties. A copy of BNL’s magnetron produced at CERN was tested at BNL and delivered at 40 kV H − beam exceeding Linac4’s nominal intensity of 80 mA. In this contribution, the performances, dynamic response to cesiation, stability and availability of these prototypes are described. The needed optimization of the emittance of H − beam above 40 mA is presented, which requires an evolution of the front end that encompasses implementation of a large ceramic insulator

On moduli spaces in AdS{sub 4} supergravity

Energy Technology Data Exchange (ETDEWEB)

Alwis, Senarath de [Colorado Univ., Boulder, CO (United States). Dept. of Physics; Louis, Jan [Hamburg Univ. (Germany). Fachbereich 12 - Physik; Hamburg Univ. (Germany). Zentrum fuer Mathematische Physik; McAllister, Liam [Cornell Univ., Ithaca, NY (United States). Dept. of Physics; Triendl, Hagen [CERN, Geneva (Switzerland). Theory Division, Physics Dept.; Westphal, Alexander [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Gruppe Theorie

2013-12-15

We study the structure of the supersymmetric moduli spaces of N=1 and N=2 supergravity theories in AdS{sub 4} backgrounds. In the N=1 case, the moduli space cannot be a complex submanifold of the Kaehler field space, but is instead real with respect to the inherited complex structure. In N=2 supergravity the same result holds for the vector multiplet moduli space, while the hypermultiplet moduli space is a Kaehler submanifold of the quaternionic-Kaehler field space. These findings are in agreement with AdS/CFT considerations.

The Rhyme of the Flying Bomb di Mervyn Peake: 125 quartine sul Blitz di Londra

Directory of Open Access Journals (Sweden)

Arianna Antonielli

2013-03-01

Full Text Available This essay addresses Mervyn Peake’s own memories of the Second World War Blitz and their migration into the poetical form of a ballad, The Rhyme of the Flying Bomb, composed in 1947. Abounding with Catholic symbolism, allegories and sea imagery, the poem tells the story of a sailor escaping from London bombing raids and his rescue of a new-born babe from a “golden drain”. The subsequent dialogue between the two protagonists reveals the fragile human side of the sailor and the divine prophetical power of the infant. Their former roles of saviour and rescued finally appear to be both spiritually and physically inverted. Written in alternating rhymes, the poem emphasizes Peake’s strong faith in humanity’s capacity to perform acts of love, despite living “at the height of a world at war”.

Three Stage Maturity Model in SME’s towards Industry 4.0

OpenAIRE

Ganzarain, Jaione; Errasti, Nekane

2016-01-01

Purpose: To address the challenges regarding the concept of Industry 4.0 and the diversification methodology and based on the strategic guidance towards Industry 4.0, we propose a process model as a guiding framework for Industry 4.0 collaborative diversification vision, strategy and action building. In this paper we suggest a stage process model to guide and train companies to identify new opportunities for diversification within Industry 4.0. Systematically carrying out the s...

Absolute emission cross sections for electron-impact excitation of Zn+(4p 2P) and (5s 2S) terms

International Nuclear Information System (INIS)

Rogers, W.T.; Dunn, G.H.; Olsen, J.O.; Reading, M.; Stefani, G.

1982-01-01

Absolute emission cross sections for electron-impact excitation of the 3d 10 4p 2 P and 3d 10 5s 2 S terms of Zn + have been measured from below threshold to about 790 eV 2 P and 390 eV 2 S using the crossed-charged-beams technique. Both transitions have the abrupt onset at threshold characteristic of positive-ion excitation. The 2 P cross section shows considerable structure in the interval from threshold to near 20 eV, above which it falls off smoothly. Agreement with five-state close-coupling theory is excellent below 100 eV when cascading is included in the theory. Above 100 eV, the data lie above the theory. The peak value of the 2 P cross section is 9.4 x 10 -16 cm 2 essentially at threshold, while the peak value of the 2 S cross section is about 0.47 x 10 -16 cm 2 . The net linear polarization of the 3d 10 4p 2 P emission was measured (unresolved from the 3d 10 4d 2 D→3d 10 4p 2 P cascading transition), and these data were used to correct the cross-section data for anisotropy of the emitted light. The effective lifetime of the 3d 9 4s 2 2 D/sub 3/2/ level was measured by observing exponential decay of the 589.6-nm photons resulting from its decay

S100A4 interacts with p53 in the nucleus and promotes p53 degradation.

Science.gov (United States)

Orre, L M; Panizza, E; Kaminskyy, V O; Vernet, E; Gräslund, T; Zhivotovsky, B; Lehtiö, J

2013-12-05

S100A4 is a small calcium-binding protein that is commonly overexpressed in a range of different tumor types, and it is widely accepted that S100A4 has an important role in the process of cancer metastasis. In vitro binding assays has shown that S100A4 interacts with the tumor suppressor protein p53, indicating that S100A4 may have additional roles in tumor development. In the present study, we show that endogenous S100A4 and p53 interact in complex samples, and that the interaction increases after inhibition of MDM2-dependent p53 degradation using Nutlin-3A. Further, using proximity ligation assay, we show that the interaction takes place in the cell nucleus. S100A4 knockdown experiments in two p53 wild-type cell lines, A549 and HeLa, resulted in stabilization of p53 protein, indicating that S100A4 is promoting p53 degradation. Finally, we demonstrate that S100A4 knockdown leads to p53-dependent cell cycle arrest and increased cisplatin-induced apoptosis. Thus, our data add a new layer to the oncogenic properties of S100A4 through its inhibition of p53-dependent processes.

One-step synthesis of graphitic-C 3 N 4 /ZnS composites for enhanced supercapacitor performance

KAUST Repository

Wei, Binbin

2017-11-24

A series of graphitic-C3N4/ZnS (g-C3N4/ZnS) supercapacitor electrode materials have been prepared via a one-step calcination process of zinc acetate/thiourea with different mass ratios under nitrogen atmosphere. The optimized g-C3N4/ZnS composite shows a highest specific capacitance of 497.7 F/g at 1 A/g and good cycling stability with capacitance retention of 80.4% at 5 A/g after 1000 cycles. Moreover, g-C3N4/ZnS composites display an improved supercapacitor performance in terms of specific capacitance compared to the pure g-C3N4 and ZnS. In addition, our designed symmetric supercapacitor device based on g-C3N4/ZnS composite electrodes can exhibit an energy density of 10.4 Wh/kg at a power density of 187.3 W/kg. As a result, g-C3N4/ZnS composites are expected to be a prospective material for supercapacitors and other energy storage applications.

One-step synthesis of graphitic-C 3 N 4 /ZnS composites for enhanced supercapacitor performance

KAUST Repository

Wei, Binbin; Liang, Hanfeng; Wang, Rongrong; Zhang, Dongfang; Qi, Zhengbing; Wang, Zhoucheng

2017-01-01

A series of graphitic-C3N4/ZnS (g-C3N4/ZnS) supercapacitor electrode materials have been prepared via a one-step calcination process of zinc acetate/thiourea with different mass ratios under nitrogen atmosphere. The optimized g-C3N4/ZnS composite shows a highest specific capacitance of 497.7 F/g at 1 A/g and good cycling stability with capacitance retention of 80.4% at 5 A/g after 1000 cycles. Moreover, g-C3N4/ZnS composites display an improved supercapacitor performance in terms of specific capacitance compared to the pure g-C3N4 and ZnS. In addition, our designed symmetric supercapacitor device based on g-C3N4/ZnS composite electrodes can exhibit an energy density of 10.4 Wh/kg at a power density of 187.3 W/kg. As a result, g-C3N4/ZnS composites are expected to be a prospective material for supercapacitors and other energy storage applications.

High resolution emission Fourier transform infrared spectra of the 4p-5s and 5p-6s bands of ArH.

Science.gov (United States)

Baskakov, O I; Civis, S; Kawaguchi, K

2005-03-15

In the 2500-8500 cm(-1) region several strong emission bands of (40)ArH were observed by Fourier transform spectroscopy through a dc glow discharge in a mixture of argon and hydrogen. Rotational-electronic transitions of the two previously unstudied 4p-5s and 5p-6s,v = 0-0, bands of (40)ArH were measured and assigned in the 6060 and 3770 cm(-1) regions, respectively. A simultaneous fit of the emission transitions of the 4p-5s and 5p-6s bands and an extended set of transitions of the 6s-4p band observed by Dabrowski, Tokaryk, and Watson [J. Mol. Spectrosc. 189, 95 (1998)] and remeasured in the present work yielded consistent values of the spectroscopic parameters of the electronic states under investigation. In the branch of the 4p-5s band with transitions of type (Q)Q(f(3)e) we observed a narrowing in the linewidths with increasing rotational quantum number N. The rotational dependence of the linewidth is caused by predissociation of the 5s state by the repulsive ground 4s state through homogeneous coupling and changes in overlap integrals of the vibrational wave functions with the rotational level. Analysis was based on the Fermi's golden rule approximation model. In the 4p-5s band region a vibrational sequence ofv(')-v(")=1-1, 2-2, and 3-3 were recorded and a number of transitions belonging to the strongest (Q)Q(f(3)e) form branch of the 1-1 band were analyzed.

Plek voor ieder kind : inclusie als opdracht voor brede scholen en kindcentra

NARCIS (Netherlands)

Doornenbal, Jeannette

Inclusie is in Nederland ver te zoeken. Ondanks het erkende belang van inclusie voor een sterke pedagogische omgeving voor kinderen. Jeannette Doornenbal pleit voor een nationale doorbraak. In dit boekje formuleert zij vier stappen om deze opdracht te realiseren: waar kan wat gedaan worden, door wie

Erwinia resistentie in Zantedeschia : eindverslag juni 2003

NARCIS (Netherlands)

Snijder, R.C.; Tuyl, van J.M.

2003-01-01

Het gewas Zantedeschia heeft zich de afgelopen jaren razendsnel ontwikkeld als nieuw siergewas. De veredeling van Zantedeschia staat echter nog in de kinderschoenen. De ontwikkeling van kennis, technieken en materiaal op het gebied van Zantedeschia is van belang met het oog op de positie die het

Laboratory investigation in normal and pathologic coagulation

NARCIS (Netherlands)

Bakhtiari, K.

2013-01-01

Kamran Bakhtiari deed onderzoek naar het gebruik en het belang van hemostase-testen in verschillende situaties, bij gezonde personen en patiënten met bloedingen of trombose. Hemostase is het proces dat zorgt voor de vloeibaarheid van het bloed en het voorkomen van bloedverlies na beschadiging van

Natuurlijke immobilisatie van zware metalen in de Roeventerpeel

NARCIS (Netherlands)

Harmsen, J.; Toorn, van den A.; Zweers, A.J.

2005-01-01

De waterbodem in Roeventerpeel is verontreinigd met cadmium en zink. Het is een voor de natuur potenteel belangrijk vengebied. Voor de ontwikkeling van dit gebied is verwijdering van de waterbodem van belang. De zware metalen in de waterbodem zijn via het grondwater aangevoerd en vastgelegd als

2012, 11/01807, (Vrijstellingsmethode niet van toepassing op Amerikaans deel van bestuurdersbeloning)

NARCIS (Netherlands)

D. Molenaar (Dick)

2012-01-01

textabstractSamenvatting: Belanghebbende is met ingang van 1 februari 2004 werkzaam als CEO bij C en vanaf 31 december 2003 als statutair bestuurder van de Amerikaanse werkmaatschappij van C. Eind 2004 heeft belanghebbende een additioneel belang in C verworven. Het verschil tussen de waarde in het

Good vibrations: Rhythms and plasticity in neural correlates of value in rat orbitofrontal cortex

NARCIS (Netherlands)

van Wingerden, E.J.M.

2013-01-01

Het verstoren van een bepaalde receptor heeft invloed op de manier waarop het rattenbrein informatie verwerkt die van belang is voor het nemen van beslissingen. In de orbitofrontale schors in de hersenen van ratten zijn neuronen actief waarvan de activiteit samenhangt met de waarde die bepaalde

Aan de slag met een arbeidshandicap : internationale ervaringen : samenvatting van de resultaten van fase 1 van het internationale onderzoeksproject Job retention and return to work strategies for disabled workers

NARCIS (Netherlands)

Vos, E.L. de; Wevers, C.W.J.

1998-01-01

Dit rapport bevat capita selecta van resultaten van de internationale studie naar strategieën die werkhervatting bevorderen van werknemers met een arbeidshandicap. Aan NIA TNO is gevraagd vooral aandacht te besteden aan resultaten die van belang zijn voor de reïntegratiepraktijk in Nederland. Aan de

Internal audit on the rise : Observaties uit de praktijk

NARCIS (Netherlands)

Paape, L.; Commandeur, H.R.; Pijl, van der G.

2005-01-01

Dit artikel behandelt enkele resultaten van vier casestudies naar de gevolgen van de invoering van corporate governance regelgeving voor internal audit in de afgelopen tien jaar. Internal audit staat in de belangstelling en lijkt aan belang te winnen. Bij de vier organisaties is nagegaan hoe het zit

Keuzeprocessen van Consumenten

NARCIS (Netherlands)

B. Wierenga (Berend)

1987-01-01

textabstractVoor de aanbieder van een voedingsmiddel, of dit nu een merkprodukt a la Mona is of een 'commodity', bijvoorbeeld karnemelk, is het van groot belang te weten welke factoren bepalen of een consument het betreffende produkt zal kiezen dan wel voor een concurrerend alternatief zal opteren.

Taksterfte in Buxus, veroorzaakt door Cylindrocladium buxicola

NARCIS (Netherlands)

Kuik, van A.J.; Dalfsen, van P.

2010-01-01

De laatste jaren wordt de Buxusteelt geplaagd door een ziekte die veroorzaakt wordt door de schimmel Cylindrocladium buxicola. Gezien de snelle uitbreiding van de ziekte is het voor kwekers en afnemers van Buxus van groot belang dat deze problematiek wordt aangepakt. Daar om is begin 2006 in

Social media invloed en reputatie: de identificatie van invloed binnen social media

NARCIS (Netherlands)

Vollenbroek, Wouter Bernardus; de Vries, Sjoerd A.; Constantinides, Efthymios

2012-01-01

Social media is een fenomeen waarvan de waarde voor organisaties niet meer wordt betwist. Betrokken binnen het bedrijfsleven erkennen het allemaal, social media spelen een rol of gaan een grote rol spelen binnen de corporate communicatie. Van groot belang hierbij is de invloed die social media

Prijspolitiek voor melk in het Verenigd Koninkrijk, België, West-Duitsland, Frankrijk en Zwitserland

NARCIS (Netherlands)

Greidanus, G.

1957-01-01

Studie van het in enkele landen gevoerde markt- en prijsbeleid voor melk en zuivel. De studie werd begonnen met vijf Europese landen, welke als afzetgebied voor de Nederlandse melk- en zuivelprodukten in meerdere of mindere mate van belang zijn: het Verenigd Koninkrijk, België, West-Duitsland,

Photoionization of gallium at 3d-4p and 4s-np (n = 5,6) resonances

International Nuclear Information System (INIS)

Caldwell, C.D.; Krause, M.O.; Jimenez-Mier, J.

1988-01-01

The simplest atoms having nonspherical symmetry are those with a single p electron in a valence shell. Of these, the group IIIB elements are excellent examples. As such, they form test cases for photoionization from open-shell systems. Through photoelectron-spectroscopy techniques, we have examined both partial cross sections and angular-distribution parameters for autoionization corresponding to promotion of a 3d electron to the 4p shell of gallium. The resulting dp 2 configuration gives rise to a complicated multiplet structure across which the angular-distribution parameter varies considerably. We have also looked at the simpler structure resulting from promotion of one s electron to an np level, n = 5,6. For these cases, the multiplet structure is simpler, but the influence of the resonance on the cross section and the angular distribution is pronounced. For the 4s4p( 3 P)5p resonance we find a value of β = -1 at the cross-section minimum. No calculations have been performed for this system, so we attempt a qualitative interpretation of our results based on an angular-momentum-transfer analysis

S100A4: a common mediator of epithelial-mesenchymal transition, fibrosis and regeneration in diseases?

DEFF Research Database (Denmark)

Schneider, M.; Sheikh, S.P.; Hansen, Jakob Lerche

2008-01-01

and neuronal injuries. Common to all these diseases is the involvement of fibrotic and inflammatory processes, i.e. processes greatly dependent on tissue remodelling, cell motility and epithelial-mesenchymal transition. Therefore, the basic biological mechanisms behind S100A4's effects are emerging. S100A4...... belongs to the S100 family of proteins that contain two Ca2+-binding sites including a canonical EF-hand motif. S100A4 is involved in the regulation of a wide range of biological effects including cell motility, survival, differentiation and contractility. S100A4 has both intracellular and extracellular...... effects. Hence, S100A4 interacts with cytoskeletal proteins and enhances metastasis of several types of cancer cells. In addition, S100A4 is secreted by unknown mechanisms, thus, paracrinely stimulating a variety of cellular responses, including angiogenesis and neuronal growth. Although many cellular...

Oscillator strengths and branching fractions of 4d75p-4d75s Rh II transitions

Science.gov (United States)

Bouazza, Safa

2017-01-01

This work reports semi-empirical determination of oscillator strengths, transition probabilities and branching fractions for Rh II 4d75p-4d75s transitions in a wide wavelength range. The angular coefficients of the transition matrix, beforehand obtained in pure SL coupling with help of Racah algebra are transformed into intermediate coupling using eigenvector amplitudes of these two configuration levels determined for this purpose; The transition integral was treated as free parameter in the least squares fit to experimental oscillator strength (gf) values found in literature. The extracted value: 5s|r1|4d75p> =2.7426 ± 0.0007 is slightly smaller than that computed by means of ab-initio method. Subsequently to oscillator strength evaluations, transition probabilities and branching fractions were deduced and compared to those obtained experimentally or through another approach like pseudo-relativistic Hartree-Fock model including core-polarization effects.