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Sample records for s10 ncrr par-07-105

  1. 32 CFR 10.5 - Construction.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Construction. 10.5 Section 10.5 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE MILITARY COMMISSIONS MILITARY COMMISSION INSTRUCTIONS § 10.5 Construction. Military Commission Instructions shall be construed in a manner consistent...

  2. 34 CFR 105.10 - Self-evaluation.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Self-evaluation. 105.10 Section 105.10 Education... DEPARTMENT OF EDUCATION § 105.10 Self-evaluation. (a) The Department shall, within one year of the effective... organizations representing individuals with handicaps to participate in the self-evaluation process by...

  3. Dosimetry of 64Cu-DOTA-AE105, a PET tracer for uPAR imaging

    DEFF Research Database (Denmark)

    Persson, Morten; El Ali, Henrik H.; Binderup, Tina

    2014-01-01

    64Cu-DOTA-AE105 is a novel positron emission tomography (PET) tracer specific to the human urokinase-type plasminogen activator receptor (uPAR). In preparation of using this tracer in humans, as a new promising method to distinguish between indolent and aggressive cancers, we have performed PET...... studies in mice to evaluate the in vivo biodistribution and estimate human dosimetry of 64Cu-DOTA-AE105. MethodsFive mice received iv tail injection of 64Cu-DOTA-AE105 and were PET/CT scanned 1, 4.5 and 22h post injection. Volume-of-interest (VOI) were manually drawn on the following organs: heart, lung......Favorable dosimetry estimates together with previously reported uPAR PET data fully support human testing of 64Cu-DOTA-AE105....

  4. 28 CFR 10.5 - Incorporation of papers previously filed.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Incorporation of papers previously filed... CARRYING ON ACTIVITIES WITHIN THE UNITED STATES Registration Statement § 10.5 Incorporation of papers previously filed. Papers and documents already filed with the Attorney General pursuant to the said act and...

  5. 46 CFR 105.45-10 - Smoking.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Smoking. 105.45-10 Section 105.45-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CARGO AND MISCELLANEOUS VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Special Operating Requirements § 105.45-10 Smoking. (a) Smoking is prohibited during and in the vicinity of the...

  6. 46 CFR 105.20-10 - Pumps.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Pumps. 105.20-10 Section 105.20-10 Shipping COAST GUARD... DISPENSING PETROLEUM PRODUCTS Specific Requirements-Cargo Tanks § 105.20-10 Pumps. (a) Pumps for cargo... discharge side of pump if the pressure under shutoff conditions exceeds 60 pounds. When a relief valve is...

  7. New peptide receptor radionuclide therapy of invasive cancer cells: in vivo studies using 177Lu-DOTA-AE105 targeting uPAR in human colorectal cancer xenografts

    International Nuclear Information System (INIS)

    Persson, Morten; Rasmussen, Palle; Madsen, Jacob; Ploug, Michael; Kjaer, Andreas

    2012-01-01

    The proposition of uPAR as a potential target in cancer therapy is advanced by its predominant expression at the invasive front of colorectal cancer (CRC) and its value as prognostic biomarker for poor survival in this disease. In this study, we provide the first in vivo proof-of-concept for a theranostic approach as treatment modality in a human xenograft colorectal cancer model. Methods: A DOTA-conjugated 9-mer high affinity uPAR binding peptide (DOTA-AE105) was radiolabeled with 64 Cu and 177 Lu, for PET imaging and targeted radionuclide therapy study, respectively. Human uPAR-positive CRC HT-29 cells were inoculated in Nude mice and treated with 177 Lu-DOTA-AE105 once a visible tumor had formed. To evaluate the true effect of the targeted radiotherapy, two controls groups were included in this study, one receiving a 177 Lu-labeled non-binding control peptide and one receiving vehicle. All animals were treated day 0 and 7. A parallel 18 F-FLT PET/CT study was performed on day 0, 1, 3 and 6. Dosimetry calculations were based on a biodistribution study, where organs and tissue of interest were collected 0.5, 1.0, 2.0, 4.0 and 24 h post injection of 177 Lu-DOTA-AE105. Toxicity was assessed by recording mouse weight and by H and E staining of kidneys in each treatment group. Results: uPAR-positive HT-29 xenograft was clearly visualized by PET/CT imaging using 64 Cu-DOTA-AE105. Subsequently, these xenograft transplants were locally irradiated using 177 Lu-DOTA-AE105, where a significant effect on tumor size and the number of uPAR-positive cells in the tumor was found (p 18 F-FLT PET/CT imaging study revealed a significant correlation between 18 F-FLT tumor uptake and efficacy of the radionuclide therapy. A histological examination of the kidneys from one animal in each treatment group did not reveal any gross abnormalities and the general performance of all treated animals also showed no indications of radioactivity-induced toxicity. Conclusion: These findings

  8. 41 CFR 105-69.105 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... services in the private sector. (o) Recipient includes all contractors, subcontractors at any tier, and... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Definitions. 105-69.105... RESTRICTIONS ON LOBBYING General § 105-69.105 Definitions. For purposes of this part: (a) Agency, as defined in...

  9. Dosimetry of 64Cu-DOTA-AE105, a PET tracer for uPAR imaging

    International Nuclear Information System (INIS)

    Persson, Morten; El Ali, Henrik H.; Binderup, Tina; Pfeifer, Andreas; Madsen, Jacob; Rasmussen, Palle; Kjaer, Andreas

    2014-01-01

    64 Cu-DOTA-AE105 is a novel positron emission tomography (PET) tracer specific to the human urokinase-type plasminogen activator receptor (uPAR). In preparation of using this tracer in humans, as a new promising method to distinguish between indolent and aggressive cancers, we have performed PET studies in mice to evaluate the in vivo biodistribution and estimate human dosimetry of 64 Cu-DOTA-AE105. Methods: Five mice received iv tail injection of 64 Cu-DOTA-AE105 and were PET/CT scanned 1, 4.5 and 22 h post injection. Volume-of-interest (VOI) were manually drawn on the following organs: heart, lung, liver, kidney, spleen, intestine, muscle, bone and bladder. The activity concentrations in the mentioned organs [%ID/g] were used for the dosimetry calculation. The %ID/g of each organ at 1, 4.5 and 22 h was scaled to human value based on a difference between organ and body weights. The scaled values were then exported to OLINDA software for computation of the human absorbed doses. The residence times as well as effective dose equivalent for male and female could be obtained for each organ. To validate this approach, of human projection using mouse data, five mice received iv tail injection of another 64 Cu-DOTA peptide-based tracer, 64 Cu-DOTA-TATE, and underwent same procedure as just described. The human dosimetry estimates were then compared with observed human dosimetry estimate recently found in a first-in-man study using 64 Cu-DOTA-TATE. Results: Human estimates of 64 Cu-DOTA-AE105 revealed the heart wall to receive the highest dose (0.0918 mSv/MBq) followed by the liver (0.0815 mSv/MBq), All other organs/tissue were estimated to receive doses in the range of 0.02–0.04 mSv/MBq. The mean effective whole-body dose of 64 Cu-DOTA-AE105 was estimated to be 0.0317 mSv/MBq. Relatively good correlation between human predicted and observed dosimetry estimates for 64 Cu-DOTA-TATE was found. Importantly, the effective whole body dose was predicted with very high

  10. Dosimetry of 64Cu-DOTA-AE105, a PET tracer for uPAR imaging.

    Science.gov (United States)

    Persson, Morten; El Ali, Henrik H; Binderup, Tina; Pfeifer, Andreas; Madsen, Jacob; Rasmussen, Palle; Kjaer, Andreas

    2014-03-01

    (64)Cu-DOTA-AE105 is a novel positron emission tomography (PET) tracer specific to the human urokinase-type plasminogen activator receptor (uPAR). In preparation of using this tracer in humans, as a new promising method to distinguish between indolent and aggressive cancers, we have performed PET studies in mice to evaluate the in vivo biodistribution and estimate human dosimetry of (64)Cu-DOTA-AE105. Five mice received iv tail injection of (64)Cu-DOTA-AE105 and were PET/CT scanned 1, 4.5 and 22 h post injection. Volume-of-interest (VOI) were manually drawn on the following organs: heart, lung, liver, kidney, spleen, intestine, muscle, bone and bladder. The activity concentrations in the mentioned organs [%ID/g] were used for the dosimetry calculation. The %ID/g of each organ at 1, 4.5 and 22 h was scaled to human value based on a difference between organ and body weights. The scaled values were then exported to OLINDA software for computation of the human absorbed doses. The residence times as well as effective dose equivalent for male and female could be obtained for each organ. To validate this approach, of human projection using mouse data, five mice received iv tail injection of another (64)Cu-DOTA peptide-based tracer, (64)Cu-DOTA-TATE, and underwent same procedure as just described. The human dosimetry estimates were then compared with observed human dosimetry estimate recently found in a first-in-man study using (64)Cu-DOTA-TATE. Human estimates of (64)Cu-DOTA-AE105 revealed the heart wall to receive the highest dose (0.0918 mSv/MBq) followed by the liver (0.0815 mSv/MBq), All other organs/tissue were estimated to receive doses in the range of 0.02-0.04 mSv/MBq. The mean effective whole-body dose of (64)Cu-DOTA-AE105 was estimated to be 0.0317 mSv/MBq. Relatively good correlation between human predicted and observed dosimetry estimates for (64)Cu-DOTA-TATE was found. Importantly, the effective whole body dose was predicted with very high precision

  11. 46 CFR 190.07-10 - Construction.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Construction. 190.07-10 Section 190.07-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS CONSTRUCTION AND ARRANGEMENT Structural Fire Protection § 190.07-10 Construction. (a) The hull, superstructure, structural...

  12. 46 CFR 92.07-10 - Construction.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Construction. 92.07-10 Section 92.07-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CARGO AND MISCELLANEOUS VESSELS CONSTRUCTION AND ARRANGEMENT Structural Fire Protection § 92.07-10 Construction. (a) The hull, superstructure, structural...

  13. Toward imaging the body at 10.5 tesla.

    Science.gov (United States)

    Ertürk, M Arcan; Wu, Xiaoping; Eryaman, Yiğitcan; Van de Moortele, Pierre-François; Auerbach, Edward J; Lagore, Russell L; DelaBarre, Lance; Vaughan, J Thomas; Uğurbil, Kâmil; Adriany, Gregor; Metzger, Gregory J

    2017-01-01

    To explore the potential of performing body imaging at 10.5 Tesla (T) compared with 7.0T through evaluating the transmit/receive performance of similarly configured dipole antenna arrays. Fractionated dipole antenna elements for 10.5T body imaging were designed and evaluated using numerical simulations. Transmit performance of antenna arrays inside the prostate, kidneys and heart were investigated and compared with those at 7.0T using both phase-only radiofrequency (RF) shimming and multi-spoke pulses. Signal-to-noise ratio (SNR) comparisons were also performed. A 10-channel antenna array was constructed to image the abdomen of a swine at 10.5T. Numerical methods were validated with phantom studies at both field strengths. Similar power efficiencies were observed inside target organs with phase-only shimming, but RF nonuniformity was significantly higher at 10.5T. Spokes RF pulses allowed similar transmit performance with accompanying local specific absorption rate increases of 25-90% compared with 7.0T. Relative SNR gains inside the target anatomies were calculated to be >two-fold higher at 10.5T, and 2.2-fold SNR gain was measured in a phantom. Gradient echo and fast spin echo imaging demonstrated the feasibility of body imaging at 10.5T with the designed array. While comparable power efficiencies can be achieved using dipole antenna arrays with static shimming at 10.5T; increasing RF nonuniformities underscore the need for efficient, robust, and safe parallel transmission methods. Magn Reson Med 77:434-443, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  14. 10 CFR 71.105 - Quality assurance program.

    Science.gov (United States)

    2010-01-01

    ... which functional compliance can be demonstrated by inspection or test; and (5) The quality history and... 10 Energy 2 2010-01-01 2010-01-01 false Quality assurance program. 71.105 Section 71.105 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PACKAGING AND TRANSPORTATION OF RADIOACTIVE MATERIAL Quality...

  15. Investigation of the total charm-pair cross section in nonresonant e+e- annihilations at √s = 10.5 GeV

    International Nuclear Information System (INIS)

    Bowcock, T.; Kinoshita, K.; Pipkin, F.M.

    1988-01-01

    We report results from two new methods for measuring the total production of charmed particles in nonresonant e + e - annihilations at √s = 10.5 GeV. The rate for detection of events containing two reconstructed charmed mesons relative to that for events containing one is used to extract information about total charm production independent of decay branching fractions. The value of ΔR/sub c//sub c-bar/, the total charm-pair cross section normalized to the pointlike μ-pair cross section, is found to be 1.13/sub -0.13//sup +0.17/ +- 0.09, under an assumption of limited particle correlations. In an independent analysis the inclusive cross section for e + e - →qq-bar→e/sup +- /X is measured to be 0.293 +- 0.017 +- 0.017 nb. Using measured relative production rates and semileptonic branching fractions of D 0 and D + mesons and estimates of these quantities for D/sub s/ and Λ/sub c/, this is found to correspond to ΔR/sub c//sub c-bar/ = 2.07 +- 0.12 +- 0.26. These two measurements are discussed in the context of measurements made by reconstruction of exclusive hadronic decay modes and of theoretical expectations

  16. New peptide receptor radionuclide therapy of invasive cancer cells: in vivo studies using 177Lu-DOTA-AE105 targeting uPAR in human colorectal cancer xenografts

    DEFF Research Database (Denmark)

    Persson, Morten; Rasmussen, Palle; Madsen, Jacob

    2012-01-01

    -of-concept for a theranostic approach as treatment modality in a human xenograft colorectal cancer model. MethodsA DOTA-conjugated 9-mer high affinity uPAR binding peptide (DOTA-AE105) was radiolabeled with 64Cu and 177Lu, for PET imaging and targeted radionuclide therapy study, respectively. Human uPAR-positive CRC HT-29...... for the first time the in vivo efficacy of an uPAR-targeted radionuclide therapeutic intervention on both tumor size and its content of uPAR expressing cells thus setting the stage for future translation into clinical use. © 2012 Elsevier Inc. All rights reserved....

  17. First (18)F-labeled ligand for PET imaging of uPAR

    DEFF Research Database (Denmark)

    Persson, Morten; Liu, Hongguang; Madsen, Jacob

    2013-01-01

    Urokinase-type plasminogen activator receptor (uPAR) is overexpressed in human prostate cancer and uPAR has been found to be associated with metastatic disease and poor prognosis. AE105 is a small linear peptide with high binding affinity to uPAR. We synthesized an N-terminal NOTA......-conjugated version (NOTA-AE105) for development of the first (18)F-labeled uPAR positron-emission-tomography PET ligand using the Al(18)F radiolabeling method. In this study, the potential of (18)F-AlF-NOTA-AE105 to specifically target uPAR-positive prostate tumors was investigated....

  18. First-in-human uPAR PET: Imaging of Cancer Aggressiveness

    Science.gov (United States)

    Persson, Morten; Skovgaard, Dorthe; Brandt-Larsen, Malene; Christensen, Camilla; Madsen, Jacob; Nielsen, Carsten H.; Thurison, Tine; Klausen, Thomas Levin; Holm, Søren; Loft, Annika; Berthelsen, Anne Kiil; Ploug, Michael; Pappot, Helle; Brasso, Klaus; Kroman, Niels; Højgaard, Liselotte; Kjaer, Andreas

    2015-01-01

    A first-in-human clinical trial with Positron Emission Tomography (PET) imaging of the urokinase-type plasminogen activator receptor (uPAR) in patients with breast, prostate and bladder cancer, is described. uPAR is expressed in many types of human cancers and the expression is predictive of invasion, metastasis and indicates poor prognosis. uPAR PET imaging therefore holds promise to be a new and innovative method for improved cancer diagnosis, staging and individual risk stratification. The uPAR specific peptide AE105 was conjugated to the macrocyclic chelator DOTA and labeled with 64Cu for targeted molecular imaging with PET. The safety, pharmacokinetic, biodistribution profile and radiation dosimetry after a single intravenous dose of 64Cu-DOTA-AE105 were assessed by serial PET and computed tomography (CT) in 4 prostate, 3 breast and 3 bladder cancer patients. Safety assessment with laboratory blood screening tests was performed before and after PET ligand injection. In a subgroup of the patients, the in vivo stability of our targeted PET ligand was determined in collected blood and urine. No adverse or clinically detectable side effects in any of the 10 patients were found. The ligand exhibited good in vivo stability and fast clearance from plasma and tissue compartments by renal excretion. In addition, high uptake in both primary tumor lesions and lymph node metastases was seen and paralleled high uPAR expression in excised tumor tissue. Overall, this first-in-human study therefore provides promising evidence for safe use of 64Cu-DOTA-AE105 for uPAR PET imaging in cancer patients. PMID:26516369

  19. Dosimetry of 64Cu-DOTA-AE105, a PET tracer for uPAR imaging

    DEFF Research Database (Denmark)

    Persson, Morten; El Ali, Henrik H.; Binderup, Tina

    2014-01-01

    64Cu-DOTA-AE105 is a novel positron emission tomography (PET) tracer specific to the human urokinase-type plasminogen activator receptor (uPAR). In preparation of using this tracer in humans, as a new promising method to distinguish between indolent and aggressive cancers, we have performed PET......, liver, kidney, spleen, intestine, muscle, bone and bladder. The activity concentrations in the mentioned organs [%ID/g] were used for the dosimetry calculation. The %ID/g of each organ at 1, 4.5 and 22h was scaled to human value based on a difference between organ and body weights. The scaled values...

  20. First-in-human uPAR PET

    DEFF Research Database (Denmark)

    Persson, Morten; Skovgaard, Dorthe; Brandt-Larsen, Malene

    2015-01-01

    A first-in-human clinical trial with Positron Emission Tomography (PET) imaging of the urokinase-type plasminogen activator receptor (uPAR) in patients with breast, prostate and bladder cancer, is described. uPAR is expressed in many types of human cancers and the expression is predictive...... for targeted molecular imaging with PET. The safety, pharmacokinetic, biodistribution profile and radiation dosimetry after a single intravenous dose of (64)Cu-DOTA-AE105 were assessed by serial PET and computed tomography (CT) in 4 prostate, 3 breast and 3 bladder cancer patients. Safety assessment...... of invasion, metastasis and indicates poor prognosis. uPAR PET imaging therefore holds promise to be a new and innovative method for improved cancer diagnosis, staging and individual risk stratification. The uPAR specific peptide AE105 was conjugated to the macrocyclic chelator DOTA and labeled with (64)Cu...

  1. 28 CFR 105.22 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Definitions. 105.22 Section 105.22... Security Officer Employment § 105.22 Definitions. As used in this subpart: (a) Authorized employer means... equipment); protect against fire, theft, misappropriation, vandalism, violence, terrorism, and other illegal...

  2. 34 CFR 105.30 - Employment.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Employment. 105.30 Section 105.30 Education Regulations... DEPARTMENT OF EDUCATION § 105.30 Employment. No qualified individual with handicaps shall, on the basis of handicap, be subjected to discrimination in employment under any program or activity conducted by the...

  3. 27 CFR 10.5 - Delegations of the Administrator.

    Science.gov (United States)

    2010-04-01

    ..., DEPARTMENT OF THE TREASURY LIQUORS COMMERCIAL BRIBERY Scope of Regulations § 10.5 Delegations of the... Administrator's Authorities in 27 CFR Part 10, Commercial Bribery. You may obtain a copy of this order by...

  4. 46 CFR 105.10-15 - Flammable liquid.

    Science.gov (United States)

    2010-10-01

    ... FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Definition of Terms Used in This Part § 105.10-15 Flammable... vapor pressure of 14 pounds or more. 1 American Society of Testing Materials Standard D 323...

  5. 32 CFR 28.105 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... services in the private sector. (o) Recipient includes all contractors, subcontractors at any tier, and... 32 National Defense 1 2010-07-01 2010-07-01 false Definitions. 28.105 Section 28.105 National... RESTRICTIONS ON LOBBYING General § 28.105 Definitions. For purposes of this part: (a) Agency, as defined in 5 U...

  6. 40 CFR 34.105 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... services in the private sector. (o) Recipient includes all contractors, subcontractors at any tier, and... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Definitions. 34.105 Section 34.105... RESTRICTIONS ON LOBBYING General § 34.105 Definitions. For purposes of this part: (a) Agency, as defined in 5 U...

  7. 29 CFR 93.105 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... services in the private sector. (o) Recipient includes all contractors, subcontractors at any tier, and... 29 Labor 1 2010-07-01 2010-07-01 true Definitions. 93.105 Section 93.105 Labor Office of the Secretary of Labor NEW RESTRICTIONS ON LOBBYING General § 93.105 Definitions. For purposes of this part: (a...

  8. 46 CFR 2.10-105 - Prepayment of annual vessel inspection fees.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Prepayment of annual vessel inspection fees. 2.10-105... VESSEL INSPECTIONS Fees § 2.10-105 Prepayment of annual vessel inspection fees. (a) Vessel owners may prepay the annual vessel inspection fee for any period of not less than three years, and not more than...

  9. 29 CFR 99.105 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Definitions. 99.105 Section 99.105 Labor Office of the Secretary of Labor AUDITS OF STATES, LOCAL GOVERNMENTS, AND NON-PROFIT ORGANIZATIONS General § 99.105 Definitions. Audit finding means deficiencies which the auditor is required by § 99.510(a) to report in the...

  10. 41 CFR 101-4.105 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Introduction § 101-4.105 Definitions. As used... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Definitions. 101-4.105 Section 101-4.105 Public Contracts and Property Management Federal Property Management Regulations System...

  11. 41 CFR 105-1.106 - Applicability.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Applicability. 105-1.106 Section 105-1.106 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1.106 Applicability...

  12. 41 CFR 105-1.109 - Numbering.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Numbering. 105-1.109 Section 105-1.109 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1.109 Numbering. ...

  13. 29 CFR 1926.105 - Safety nets.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 8 2010-07-01 2010-07-01 false Safety nets. 1926.105 Section 1926.105 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Personal Protective and Life Saving Equipment § 1926.105...

  14. 41 CFR 105-74.665 - State.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false State. 105-74.665 Section 105-74.665 Public Contracts and Property Management Federal Property Management Regulations System...-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74.665 State. State...

  15. 41 CFR 105-74.630 - Debarment.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Debarment. 105-74.630 Section 105-74.630 Public Contracts and Property Management Federal Property Management Regulations System...-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74.630 Debarment...

  16. 41 CFR 105-74.605 - Award.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Award. 105-74.605 Section 105-74.605 Public Contracts and Property Management Federal Property Management Regulations System...-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74.605 Award. Award...

  17. 41 CFR 105-74.660 - Recipient.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Recipient. 105-74.660 Section 105-74.660 Public Contracts and Property Management Federal Property Management Regulations System...-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74.660 Recipient...

  18. 41 CFR 105-74.670 - Suspension.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Suspension. 105-74.670 Section 105-74.670 Public Contracts and Property Management Federal Property Management Regulations System...-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74.670 Suspension...

  19. 41 CFR 105-74.615 - Conviction.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Conviction. 105-74.615 Section 105-74.615 Public Contracts and Property Management Federal Property Management Regulations System...-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74.615 Conviction...

  20. 41 CFR 105-74.655 - Individual.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Individual. 105-74.655 Section 105-74.655 Public Contracts and Property Management Federal Property Management Regulations System...-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74.655 Individual...

  1. 41 CFR 105-74.650 - Grant.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Grant. 105-74.650 Section 105-74.650 Public Contracts and Property Management Federal Property Management Regulations System...-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74.650 Grant. Grant...

  2. 41 CFR 105-68.995 - Principal.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Principal. 105-68.995 Section 105-68.995 Public Contracts and Property Management Federal Property Management Regulations System...-GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 105-68.995 Principal. Principal means— (a...

  3. 41 CFR 105-1.110 - Deviation.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Deviation. 105-1.110 Section 105-1.110 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1.110 Deviation. (a...

  4. 41 CFR 105-1.150 - Citation.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Citation. 105-1.150 Section 105-1.150 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1.150 Citation. (a...

  5. 34 CFR 300.105 - Assistive technology.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Assistive technology. 300.105 Section 300.105 Education... DISABILITIES State Eligibility Other Fape Requirements § 300.105 Assistive technology. (a) Each public agency must ensure that assistive technology devices or assistive technology services, or both, as those terms...

  6. 17 CFR 10.105 - Review by Commission on its own initiative.

    Science.gov (United States)

    2010-04-01

    ... own initiative. 10.105 Section 10.105 Commodity and Securities Exchanges COMMODITY FUTURES TRADING... initiative. The Commission may on its own initiative, within 30 days after the initial decision has been... the Commission has directed review on its own initiative shall be served on all parties by the...

  7. 29 CFR 1910.105 - Nitrous oxide.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 5 2010-07-01 2010-07-01 false Nitrous oxide. 1910.105 Section 1910.105 Labor Regulations... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Hazardous Materials § 1910.105 Nitrous oxide. The piped systems for the in-plant transfer and distribution of nitrous oxide shall be designed, installed, maintained, and...

  8. 40 CFR 94.105 - Duty cycles.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Duty cycles. 94.105 Section 94.105... EMISSIONS FROM MARINE COMPRESSION-IGNITION ENGINES Test Procedures § 94.105 Duty cycles. (a) Overview. For....8(e), engines shall be tested using the appropriate duty cycles described in this section. (b...

  9. Development of a Tetrathioether (S4) Bifunctional Chelate System for Rh-105

    Science.gov (United States)

    2013-07-01

    olt s...500 0 500 1000 1500 mV olt s -500 0 500 1000 1500 (B) Free Rhodium Chloride Minutes 0 2 4 6 8 10 12 mV olt s 0 2000 4000 mV olt s 0 2000 4000 (C) Rh-S4...Diol prepared in water Minutes 0 2 4 6 8 10 12 mV olts 0 2000 4000 mV olts 0 2000 4000 (D) 105 Rh-S4Diol with cold [Rh-S4(OH)2-Diol] +

  10. 40 CFR 65.105 - Leak repair.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Leak repair. 65.105 Section 65.105... FEDERAL AIR RULE Equipment Leaks § 65.105 Leak repair. (a) Leak repair schedule. The owner or operator shall repair each leak detected as soon as practical but not later than 15 calendar days after it is...

  11. 41 CFR 105-74.620 - Cooperative agreement.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Cooperative agreement. 105-74.620 Section 105-74.620 Public Contracts and Property Management Federal Property Management... Administration 74-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74...

  12. 41 CFR 105-74.610 - Controlled substance.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Controlled substance. 105-74.610 Section 105-74.610 Public Contracts and Property Management Federal Property Management... Administration 74-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74...

  13. 41 CFR 105-1.109-51 - Arrangement.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Arrangement. 105-1.109-51 Section 105-1.109-51 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1...

  14. 41 CFR 105-54.304 - Cost guidelines.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Cost guidelines. 105-54.304 Section 105-54.304 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.3-Advisory Committee Procedures § 105-54.304 Cost guidelines...

  15. 36 CFR 1211.105 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Definitions. 1211.105 Section 1211.105 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION GENERAL RULES... the sale or transfer of such property, if the Federal share of the fair market value of the property...

  16. 41 CFR 105-8.170-13 - Delegation.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Delegation. 105-8.170-13 Section 105-8.170-13 Public Contracts and Property Management Federal Property Management Regulations... HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY GENERAL SERVICES ADMINISTRATION § 105-8.170-13 Delegation...

  17. 41 CFR 105-1.101-50 - Exclusions.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Exclusions. 105-1.101-50 Section 105-1.101-50 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1.101-50...

  18. 38 CFR 45.105 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... private sector. (o) Recipient includes all contractors, subcontractors at any tier, and subgrantees at any... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Definitions. 45.105... RESTRICTIONS ON LOBBYING General § 45.105 Definitions. For purposes of this part: (a) Agency, as defined in 5 U...

  19. 41 CFR 105-68.905 - Affiliate.

    Science.gov (United States)

    2010-07-01

    ... management, ownership, or principal employees as the excluded person. ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Affiliate. 105-68.905 Section 105-68.905 Public Contracts and Property Management Federal Property Management Regulations System...

  20. 33 CFR 105.415 - Amendment and audit.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Amendment and audit. 105.415 Section 105.415 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MARITIME SECURITY MARITIME SECURITY: FACILITIES Facility Security Plan (FSP) § 105.415 Amendment and audit. (a) Amendments. (1) Amendments to a Facility Securit...

  1. 29 CFR 541.105 - Particular weight.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Particular weight. 541.105 Section 541.105 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS DEFINING AND DELIMITING THE EXEMPTIONS FOR EXECUTIVE, ADMINISTRATIVE, PROFESSIONAL, COMPUTER AND OUTSIDE SALES EMPLOYEES...

  2. 41 CFR 105-74.301 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false [Reserved] 105-74.301 Section 105-74.301 Public Contracts and Property Management Federal Property Management Regulations System...-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Who Are...

  3. 33 CFR 105.145 - Maritime Security (MARSEC) Directive.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Maritime Security (MARSEC) Directive. 105.145 Section 105.145 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MARITIME SECURITY MARITIME SECURITY: FACILITIES General § 105.145 Maritime Security (MARSEC...

  4. 41 CFR 105-70.021 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Discovery. 105-70.021 Section 105-70.021 Public Contracts and Property Management Federal Property Management Regulations System..., papers, and other data and documentary evidence. Nothing contained herein shall be interpreted to require...

  5. 28 CFR 105.27 - Miscellaneous provisions.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Miscellaneous provisions. 105.27 Section 105.27 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CRIMINAL HISTORY BACKGROUND CHECKS... has elected to opt out; or (ii) A participating State that has not yet established a process for...

  6. 41 CFR 105-74.625 - Criminal drug statute.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Criminal drug statute. 105-74.625 Section 105-74.625 Public Contracts and Property Management Federal Property Management... Administration 74-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74...

  7. 41 CFR 105-74.635 - Drug-free workplace.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Drug-free workplace. 105-74.635 Section 105-74.635 Public Contracts and Property Management Federal Property Management... Administration 74-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74...

  8. 40 CFR 59.105 - Reporting requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Reporting requirements. 59.105 Section... Volatile Organic Compound Emission Standards for Automobile Refinish Coatings § 59.105 Reporting requirements. (a) Each regulated entity must submit an initial report no later than January 11, 1999 or within...

  9. 41 CFR 105-8.160 - Communications.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Communications. 105-8.160 Section 105-8.160 Public Contracts and Property Management Federal Property Management Regulations... would result in a fundamental alteration in the nature of a program or activity or in undue financial...

  10. 41 CFR 105-56.031 - Notice.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Notice. 105-56.031 Section 105-56.031 Public Contracts and Property Management Federal Property Management Regulations System... the amount of offset taken; (ii) The identity of the creditor agency identified by the disbursing...

  11. 41 CFR 105-1.109-52 - Cross-references.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Cross-references. 105-1.109-52 Section 105-1.109-52 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1...

  12. 41 CFR 105-1.100 - Scope of subpart.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Scope of subpart. 105-1.100 Section 105-1.100 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1.100...

  13. 41 CFR 128-1.105 - Authority for JPMR.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Authority for JPMR. 128-1.105 Section 128-1.105 Public Contracts and Property Management Federal Property Management Regulations System (Continued) DEPARTMENT OF JUSTICE 1-INTRODUCTION 1.1-Regulation System § 128-1.105...

  14. 41 CFR 105-1.109-50 - General plan.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false General plan. 105-1.109-50 Section 105-1.109-50 Public Contracts and Property Management Federal Property Management....109-50 General plan. Chapter 105 is divided into parts, subparts, and further subdivisions as...

  15. Permanent magnets prepared from Sm10.5Fe88.5Zr1.0Ny without homogenization

    International Nuclear Information System (INIS)

    Gebel, B.; Kubis, M.; Mueller, K.-H.

    1997-01-01

    In as-cast Sm 2 Fe 17 the high amount of α-Fe caused by a peritectic reaction can be considerably reduced by a small addition of about 1 at% Zr. X-ray diffraction showed that as-cast Sm 10.5 Fe 88.5 Zr 1.0 mainly consists of a phase with the Th 2 Zn 17 -type structure and SmFe 3 . Non-homogenized Sm 10.5 Fe 88.5 Zr 1.0 was milled and (i) annealed in vacuum or (ii) treated with a hydrogenation-disproportionation-desorp tion-recombination (HDDR) process. The annealed and subsequently nitrogenated powder is magnetically anisotropic and has a coercivity μ 0J H C up to 2.0 T and an energy product (BH) max up to 136 kJ/m 3 . HDDR-treated and nitrogenated powder is isotropic and exhibits values of μ 0J H C = 3.1 T and (BH) max 103 kJ/m 3 . Consequently, Sm 10.5 Fe 88.5 Zr 1.0 N y (y ∼ 16) permanent magnets with very good properties can be prepared without the time-consuming homogenization procedure. (orig.)

  16. 41 CFR 105-74.640 - Employee.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Employee. 105-74.640...-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74.640 Employee. (a) Employee means the employee of a recipient directly engaged in the performance of work under the award...

  17. 41 CFR 105-70.033 - Witnesses.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Witnesses. 105-70.033 Section 105-70.033 Public Contracts and Property Management Federal Property Management Regulations System... may proceed by leading questions only if the witness is a hostile witness, an adverse party, or a...

  18. 41 CFR 105-56.021 - Notice.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Notice. 105-56.021 Section 105-56.021 Public Contracts and Property Management Federal Property Management Regulations System... description of the payment and the amount of offset taken; (ii) The identity of GSA as the creditor agency...

  19. 41 CFR 105-68.1005 - State.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false State. 105-68.1005...-GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 105-68.1005 State. (a) State means— (1) Any of the states of the United States; (2) The District of Columbia; (3) The Commonwealth of Puerto...

  20. 41 CFR 105-71.144 - Termination for convenience.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Termination for convenience. 105-71.144 Section 105-71.144 Public Contracts and Property Management Federal Property... Termination for convenience. Except as provided in § 105-71.143 awards may be terminated in whole or in part...

  1. 41 CFR 105-71.133 - Supplies.

    Science.gov (United States)

    2010-07-01

    ... aggregate fair market value upon termination or completion of the award, and if the supplies are not needed... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Supplies. 105-71.133...-Award Requirements/Changes, Property, and Subawards § 105-71.133 Supplies. (a) Title. Title to supplies...

  2. 48 CFR 39.105 - Privacy.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Privacy. 39.105 Section 39... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY General 39.105 Privacy. Agencies shall ensure that contracts for information technology address protection of privacy in accordance with the Privacy Act (5 U.S.C...

  3. 40 CFR 133.105 - Treatment equivalent to secondary treatment.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Treatment equivalent to secondary treatment. 133.105 Section 133.105 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS SECONDARY TREATMENT REGULATION § 133.105 Treatment equivalent to secondary treatment...

  4. PET imaging of urokinase-type plasminogen activator receptor (uPAR) in prostate cancer

    DEFF Research Database (Denmark)

    Skovgaard, Dorthe; Persson, Morten; Kjaer, Andreas

    2016-01-01

    Overexpression of urokinase-type plasminogen activator receptors (uPAR) represents an important biomarker for aggressiveness in most common malignant diseases, including prostate cancer (PC). Accordingly, uPAR expression either assessed directly in malignant PC tissue or assessed directly in plasma...... and prognostic imaging method. In this review, we will focus on the recent development of uPAR PET and the relevance within prostate cancer imaging. Novel antibody and small-molecule radiotracers-targeting uPAR, including a series of uPAR-targeting PET ligands, based on the high affinity peptide ligand AE105......, have been synthesized and tested in vitro and in vivo in preclinical murine xenograft models and, recently, in a first-ever clinical uPAR PET study in cancer patients, including patients with PC. In this phase I study, a high and specific uptake of the tracer 64Cu-DOTA-AE105 was found in both primary...

  5. 41 CFR 105-72.307 - Allowable costs.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Allowable costs. 105-72.307 Section 105-72.307 Public Contracts and Property Management Federal Property Management... Administration 72-UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER...

  6. 10 CFR 431.105 - Materials incorporated by reference.

    Science.gov (United States)

    2010-01-01

    ..._regulations/ibr_locations.html. (ii) U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Hearings and Dockets, “Test Procedures and Efficiency Standards for Commercial Water Heaters, Hot....105 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL...

  7. 41 CFR 105-74.645 - Federal agency or agency.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Federal agency or agency. 105-74.645 Section 105-74.645 Public Contracts and Property Management Federal Property Management... Administration 74-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 105-74...

  8. 41 CFR 105-68.920 - Civil judgment.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Civil judgment. 105-68... Administration 68-GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 105-68.920 Civil judgment. Civil judgment means the disposition of a civil action by any court of competent jurisdiction...

  9. 28 CFR 34.105 - Peer review methods.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Peer review methods. 34.105 Section 34... Review § 34.105 Peer review methods. (a) For both competitive and noncompetitive applications, peer... announcement or otherwise established by the Administrator, together with the assignment of numerical values...

  10. 41 CFR 105-72.504 - Procurement procedures.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Procurement procedures. 105-72.504 Section 105-72.504 Public Contracts and Property Management Federal Property Management... acceptable characteristics or minimum acceptable standards. (iv) The specific features of “brand name or...

  11. 40 CFR 89.105 - Certificate of conformity.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Certificate of conformity. 89.105... and Certification Provisions § 89.105 Certificate of conformity. Every manufacturer of a new nonroad compression-ignition engine must obtain a certificate of conformity covering the engine family, as described...

  12. 33 CFR 105.290 - Additional requirements-cruise ship terminals.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Additional requirements-cruise ship terminals. 105.290 Section 105.290 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MARITIME SECURITY MARITIME SECURITY: FACILITIES Facility Security Requirements § 105.290 Additional requirements—cruise ship terminals...

  13. 41 CFR 105-60.608 - Fees, expenses, and costs.

    Science.gov (United States)

    2010-07-01

    ... Demands in Judicial or Administrative Proceedings § 105-60.608 Fees, expenses, and costs. (a) In... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Fees, expenses, and costs. 105-60.608 Section 105-60.608 Public Contracts and Property Management Federal Property...

  14. Improved PET Imaging of uPAR expression using new Cu-64-labeled cross-bridged peptide ligands

    DEFF Research Database (Denmark)

    Persson, Morten; Hosseini, Masood; Madsen, Jacob

    2013-01-01

    The correlation between uPAR expression, cancer cell invasion and metastases is now well-established and has prompted the development of a number of uPAR PET imaging agents, which could potentially identify cancer patients with invasive and metastatic lesions. In the present study, we synthesized......, the more stable of the new uPAR PET tracers, (64)Cu-CB-TE2A-PA-AE105, exhibits a significantly reduced liver uptake compared to (64)Cu-DOTA-AE105 as well as (64)Cu-CB-TE2A-AE105, (p...... and characterized two new cross-bridged (64)Cu-labeled peptide conjugates for PET imaging of uPAR and performed a head-to-head comparison with the corresponding and more conventionally used DOTA conjugate. Based on in-source laser-induced reduction of chelated Cu(II) to Cu(I), we now demonstrate the following...... ranking with respect to the chemical inertness of their complexed Cu ions: DOTA-AE105 95%) were achieved in all cases by incubation at 95ºC. In vivo, they display identical tumor uptake after 1h, but differ significantly after 22 hrs, where the DOTA-AE105 uptake remains surprisingly high. Importantly...

  15. 41 CFR 105-70.019 - Prehearing conferences.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Prehearing conferences. 105-70.019 Section 105-70.019 Public Contracts and Property Management Federal Property Management... party chooses to waive appearance at an oral hearing and to submit only documentary evidence (subject to...

  16. 41 CFR 105-60.305-1 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... to the public and to private sector organizations; (2) Ensure that groups and individuals pay the... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Definitions. 105-60.305..., Orders, Policies, Interpretations, Manuals, and Instructions § 105-60.305-1 Definitions. For the purpose...

  17. 41 CFR 105-1.000-50 - Scope of part.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Scope of part. 105-1.000-50 Section 105-1.000-50 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION § 105-1.000-50 Scope of part...

  18. 41 CFR 105-56.008 - Pre-offset paper hearing.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Pre-offset paper hearing. 105-56.008 Section 105-56.008 Public Contracts and Property Management Federal Property Management... General Services Administration Employees § 105-56.008 Pre-offset paper hearing. If a hearing is to be...

  19. 41 CFR 105-72.304 - Program income.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Program income. 105-72... Management § 105-72.304 Program income. (a) Federal awarding agencies shall apply the standards set forth in this section in requiring recipient organizations to account for program income related to projects...

  20. 41 CFR 105-71.125 - Program income.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Program income. 105-71... GOVERNMENTS 71.12-Post-Award Requirements/Financial Administration § 105-71.125 Program income. (a) General. Grantees are encouraged to earn income to defray program costs. Program income includes income from fees...

  1. 41 CFR 105-71.141 - Financial reporting.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Financial reporting. 105... GOVERNMENTS 71.14-Post-Award Requirements/Reports, Records, Retention, and Enforcement § 105-71.141 Financial reporting. (a) General. (1) Except as provided in paragraphs (a) (2) and (5) of this section, grantees will...

  2. Dosimeter configurations for the measurement of Hs(0.07) and Hp(10) from photons

    DEFF Research Database (Denmark)

    Christensen, P.; Bøtter-Jensen, L.; Ennow, K.

    1990-01-01

    F TLD-700, LiF:Mg, Cu, P, and Li2B4O7:Mn TL detectors were investigated for the measurement of H(p) (10), and graphite-mixed MgB4O7:Dy, LiF and Li2B4O7 were investigated for the measurement of H(s) (0.07). Irradiations were made with a Co-60 gamma source and ISO qualities of X radiations...

  3. Les Brulures Electriques par Haut Voltage - A Propos de 10 Cas

    Science.gov (United States)

    Belmir, R.; Fejjal, N.; El Omari, M.; El Mazouz, S.; Gharib, N.; Abassi, A.; Belmahi, A.

    2008-01-01

    Summary Les accidents électriques par haute tension (AEHT) provoquent des brûlures profondes par effet Joule le long des axes vasculo-nerveux entre les points d'entrée et de sortie, qui sont le siège de lésions délabrantes. Les Auteurs rapportent une série de dix cas d'AEHT admis au service de chirurgie réparatrice et de brûlés de l'Hôpital Ibn Sina de Rabat à travers laquelle ils étudient les caractéristiques épidémiologiques, cliniques et thérapeutiques. Tous les patients étaient des adultes de sexe masculin dont l'âge moyen était de 31 ans. Dans 70% des cas, ces brûlures étaient secondaires à un contact avec les distributeurs d'électricité avec une surface brûlée inférieure à 20%. Le traitement des lésions électrothermiques a nécessité des interventions itératives avec amputation des segments de membres nécrosés dans 70% des cas, dont les suites étaient marquées par des séquelles fonctionnelles invalidantes. La prévention des AEHT, en particulier pour les accidents du travail au sein des professions exposées, reste fondamentale. PMID:21991124

  4. 41 CFR 105-56.018 - Salary offset.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Salary offset. 105-56... Administration 56-SALARY OFFSET FOR INDEBTEDNESS OF FEDERAL EMPLOYEES TO THE UNITED STATES Centralized Salary Offset (CSO) Procedures-GSA as Creditor Agency § 105-56.018 Salary offset. When a match occurs and all...

  5. 41 CFR 105-56.028 - Salary offset.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Salary offset. 105-56... Administration 56-SALARY OFFSET FOR INDEBTEDNESS OF FEDERAL EMPLOYEES TO THE UNITED STATES Centralized Salary Offset (CSO) Procedures-GSA as Paying Agency § 105-56.028 Salary offset. When a match occurs and all...

  6. 41 CFR 105-50.001-1 - State.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false State. 105-50.001-1... System (Continued) GENERAL SERVICES ADMINISTRATION 50-PROVISION OF SPECIAL OR TECHNICAL SERVICES TO STATE AND LOCAL UNITS OF GOVERNMENT § 105-50.001-1 State. State means any of the several States of the...

  7. 31 CFR 0.105 - Deputy Ethics Official.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Deputy Ethics Official. 0.105 Section... EMPLOYEE RULES OF CONDUCT General Provisions Responsibilities § 0.105 Deputy Ethics Official. The Chief Counsel or Legal Counsel for a bureau, or a designee, is the Deputy Ethics Official for that bureau. The...

  8. 41 CFR 105-72.602 - Financial reporting.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Financial reporting. 105... § 105-72.602 Financial reporting. (a) The following forms or such other forms as may be approved by OMB are authorized for obtaining financial information from recipients. (1) SF-269 or SF-269A, Financial...

  9. 41 CFR 105-8.150-2 - Methods.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Methods. 105-8.150-2... HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY GENERAL SERVICES ADMINISTRATION § 105-8.150-2 Methods. (a... construction of new facilities, use of accessible rolling stock, or any other methods that result in making its...

  10. 41 CFR 105-53.134 - Office of Administration.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Office of Administration. 105-53.134 Section 105-53.134 Public Contracts and Property Management Federal Property Management... Associate Administrator for Administration, participates in the executive leadership of the agency...

  11. Protein engineering of CYP105s for their industrial uses.

    Science.gov (United States)

    Yasuda, Kaori; Sugimoto, Hiroshi; Hayashi, Keiko; Takita, Teisuke; Yasukawa, Kiyoshi; Ohta, Miho; Kamakura, Masaki; Ikushiro, Shinichi; Shiro, Yoshitsugu; Sakaki, Toshiyuki

    2018-01-01

    Cytochrome P450 enzymes belonging to the CYP105 family are predominantly found in bacteria belonging to the phylum Actinobacteria and the order Actinomycetales. In this review, we focused on the protein engineering of P450s belonging to the CYP105 family for industrial use. Two Arg substitutions to Ala of CYP105A1 enhanced its vitamin D 3 25- and 1α-hydroxylation activities by 400 and 100-fold, respectively. The coupling efficiency between product formation and NADPH oxidation was largely improved by the R84A mutation. The quintuple mutant Q87W/T115A/H132L/R194W/G294D of CYP105AB3 showed a 20-fold higher activity than the wild-type enzyme. Amino acids at positions 87 and 191 were located at the substrate entrance channel, and that at position 294 was located close to the heme group. Semi-rational engineering of CYP105A3 selected the best performing mutant, T85F/T119S/V194N/N363Y, for producing pravastatin. The T119S and N363Y mutations synergistically had remarkable effects on the interaction between CYP105A3 and putidaredoxin. Although wild-type CYP105AS1 hydroxylated compactin to 6-epi-pravastatin, the quintuple mutant I95T/Q127R/A180V/L236I/A265N converted almost all compactin to pravastatin. Five amino acid substitutions by two rounds of mutagenesis almost completely changed the stereo-selectivity of CYP105AS1. These results strongly suggest that the protein engineering of CYP105 enzymes greatly increase their industrial utility. This article is part of a Special Issue entitled: Cytochrome P450 biodiversity and biotechnology, edited by Erika Plettner, Gianfranco Gilardi, Luet Wong, Vlada Urlacher, Jared Goldstone. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. 41 CFR 105-1.102 - Relationship of GSPMR to FPMR.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Relationship of GSPMR to FPMR. 105-1.102 Section 105-1.102 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1...

  13. Safety, Dosimetry, and Tumor Detection Ability of 68Ga-NOTA-AE105

    DEFF Research Database (Denmark)

    Skovgaard Lund, Dorthe; Persson, Morten; Brandt-Larsen, Malene

    2017-01-01

    The overexpression of urokinase-type plasminogen activator receptors (uPARs) represents an established biomarker for aggressiveness in most common malignant diseases, including breast cancer (BC), prostate cancer (PC), and urinary bladder cancer (UBC), and is therefore an important target for new...... cancer therapeutic and diagnostic strategies. In this study, uPAR PET imaging using a68Ga-labeled version of the uPAR-targeting peptide (AE105) was investigated in a group of patients with BC, PC, and UBC. The aim of this first-in-human, phase I clinical trial was to investigate the safety.......Conclusion:This first-in-human, phase I clinical trial demonstrates the safe use and clinical potential of68Ga-NOTA-AE105 as a new radioligand for uPAR PET imaging in cancer patients....

  14. Parijs is een meervoud. Adriaan van Dis en de heruitvinding van de Hollander in Parijs

    NARCIS (Netherlands)

    Koffeman, M.N.; Koffeman, Maaike; Montoya, Alicia C.; Smeets, Marc

    2017-01-01

    Parijs, tot halverwege de 20ste eeuw het onbetwiste centrum van de Europese cultuur, heeft van oudsher een grote aantrekkingskracht uitgeoefend op Nederlandse kunstenaars en schrijvers. Velen van hen verbleven er kortere of langere tijd, op zoek naar internationale erkenning. De vrijere seksuele moraal

  15. 41 CFR 105-72.204 - Special award conditions.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Special award conditions. 105-72.204 Section 105-72.204 Public Contracts and Property Management Federal Property Management... award conditions. If an applicant or recipient: (a) Has a history of poor performance, (b) Is not...

  16. 41 CFR 105-1.104 - Publication of GSPMR.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Publication of GSPMR. 105-1.104 Section 105-1.104 Public Contracts and Property Management Federal Property Management....104 Publication of GSPMR. (a) Most GSPMR are published in the Federal Register. This practice helps to...

  17. ¡París!

    Directory of Open Access Journals (Sweden)

    Beatriz Caballero

    2003-01-01

    Full Text Available El día no le alcanzaba para caminarlo. Conocía cada puente, cada calle,plaza, museo, rincón, iglesia, café, y la mesa con el mejor ángulo para mirar siempre una iglesia, ojalá Saint-Germain-des-Pres, o Notre-Dame. Siempre contaba la impresión que le había causado a Bolívar ver allí cuando el papa coronó a Napoleón. Él se iba para la oficina todos los días, Luis a un taller a pintar, Antonio a estudiar ciencias políticas, yo al colegio y mamá hacía las cosas prácticas. Aprendíamos francés todos al tiempo y por la noche nos contábamos lo nuevo que cada uno había aprendido. Mamá después, cuando ya se quería volver, decía que París nos había maleado a todos. Estaba en pleno furor el cine francés de la "nueva ola", pero ella sólo me llevaba a ver películas de vaqueros pues no se fiaba de la clasificación de los periódicos.

  18. 41 CFR 105-70.041 - Stay pending appeal.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Stay pending appeal. 105... Administration 70-IMPLEMENTATION OF THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 105-70.041 Stay pending appeal. (a) An initial decision is stayed automatically pending disposition of a motion for reconsideration...

  19. 41 CFR 105-1.101 - General Services Administration Property Management Regulations.

    Science.gov (United States)

    2010-07-01

    ...-INTRODUCTION 1.1-Regulations System § 105-1.101 General Services Administration Property Management Regulations... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false General Services Administration Property Management Regulations. 105-1.101 Section 105-1.101 Public Contracts and Property...

  20. 41 CFR 105-60.405 - Processing requests for confidential commercial information.

    Science.gov (United States)

    2010-07-01

    ... MATERIALS 60.4-Described Records § 105-60.405 Processing requests for confidential commercial information... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Processing requests for confidential commercial information. 105-60.405 Section 105-60.405 Public Contracts and Property Management...

  1. 41 CFR 105-53.140 - Office of Operations and Industry Relations.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Office of Operations and Industry Relations. 105-53.140 Section 105-53.140 Public Contracts and Property Management Federal Property... FUNCTIONS Central Offices § 105-53.140 Office of Operations and Industry Relations. The Office of Operations...

  2. Causes de décès des patients infectés par le VIH dans le Centre tunisien

    Science.gov (United States)

    Chelli, Jihène; Bellazreg, Foued; Aouem, Abir; Hattab, Zouhour; Mesmia, Hèla; Lasfar, Nadia Ben; Hachfi, Wissem; Masmoudi, Tasnim; Chakroun, Mohamed; Letaief, Amel

    2016-01-01

    La trithérapie antirétrovirale a contribué à une baisse considérable de la mortalité liée au VIH. Les causes de décès sont dominées par les infections opportunistes dans les pays en voie de développement et par les maladies cardiovasculaires et les cancers dans les pays développés. L’objectif était de déterminer les causes et les facteurs de risque de décès des patients infectés par le VIH dans le Centre Tunisien. Une étude transversale auprès des patients infectés par le VIH âgés de plus de 15 ans suivis à Sousse et à Monastir entre 2000 et 2014. Le décès était considéré lié au VIH si la cause était un évènement classant SIDA ou s’il était la conséquence d’une infection opportuniste d’étiologie indéterminée avec des CD4 VIH si la cause n’était pas un évènement classant SIDA, et de cause inconnue si aucune information n’était disponible. Deux cents treize patients, 130 hommes (61%) et 83 femmes (39%), d’âge moyen 40±11 ans ont été inclus. Cinquante quatre patients sont décédés, avec une mortalité de 5,4/100 patients-années. La mortalité annuelle a baissé de 5,8% en 2000-2003 à 2,3% en 2012-2014. La survie était de 72% à 5 ans et de 67% à 10 ans. Les décès étaient liés au VIH dans 70,4% des cas. Les causes de décès les plus fréquentes étaient la pneumocystose pulmonaire et la cryptococcose neuroméningée dans 6 cas (11%) chacune. Les facteurs de risque de décès étaient les antécédents d’infections opportunistes, la durée de la trithérapie antirétrovirale VIH en Tunisie. PMID:28292068

  3. 41 CFR 101-1.105 - Authority for FPMR System.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Authority for FPMR System. 101-1.105 Section 101-1.105 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 1-INTRODUCTION 1.1-Regulation System § 101...

  4. Valorisation de l’eau par l’élevage bovin : enseignements tirés de longs suivis d’exploitations dans le plateau du Saïs

    Directory of Open Access Journals (Sweden)

    Mohamed Taher Sraïri

    2016-10-01

    Full Text Available La contrainte hydrique constitue un facteur limitant avéré de la production agricole dans un pays aride à semi-aride comme le Maroc. Dans cette étude, la valorisation de l’eau par l’élevage bovin a été étudiée, dans des exploitations du plateau du Saïs irriguant à partir de la nappe et/ou de sources. Le protocole de recherche a caractérisé les termes de la valorisation volumétrique et économique de l’eau par l’élevage bovin, par l’adoption d’une série de visites mensuelles à quatre exploitations au cours de deux années successives : 2014 et 2015. Les objectifs de ces suivis visaient : i la détermination des volumes d’eau utilisés, en prenant en compte la diversité de leurs origines (précipitations, eau d’irrigation de surface ou souterraine, et eau virtuelle correspondant aux volumes utilisés pour la production des aliments achetés à l’extérieur de l’exploitation, ii les quantités de biomasse des fourrages fauchés, iii le suivi des rations distribuées aux vaches et celles destinées à leur descendance ainsi que leurs contenus en nutriments (énergie et azote, et iv les quantités de lait et de viande produites. Les résultats démontrent que l’élevage bovin est surtout lié à l’eau pluviale et, à un degré moindre, à l’eau virtuelle puisque ces sources hydriques représentent respectivement 52,5 et 31,7 % des besoins totaux pour produire du lait et 37,9 et 57,5 % pour produire de la viande. L’élevage bovin ne mobilise que très peu l’eau souterraine qui représente en moyenne 7,6 et 0,7 % des besoins hydriques pour produire du lait et de la viande. Les empreintes hydriques moyennes pour les productions bovines, définies comme la somme des consommations d’eau de toutes origines, étaient respectivement de 1,33 m3 par litre de lait et 7,5 m3 par kg de poids vif. Les valorisations économiques de l’eau d’irrigation par l’élevage bovin étaient de 3,8 et 15,5 DH par m3

  5. 41 CFR 105-68.350 - What must I do if I learn of information required under § 105-68.335 after entering into a...

    Science.gov (United States)

    2010-07-01

    ... General Services Administration? 105-68.350 Section 105-68.350 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What must I do if I...

  6. 41 CFR 105-50.303 - Cost basis in lieu of fees.

    Science.gov (United States)

    2010-07-01

    ... § 105-50.303 Cost basis in lieu of fees. Where the cost of services is to be recovered on other than a... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Cost basis in lieu of fees. 105-50.303 Section 105-50.303 Public Contracts and Property Management Federal Property...

  7. 10 CFR 1304.105 - Requests for access to records.

    Science.gov (United States)

    2010-01-01

    ... Energy NUCLEAR WASTE TECHNICAL REVIEW BOARD PRIVACY ACT OF 1974 § 1304.105 Requests for access to records... request access to his or her own records in writing by addressing a letter to: Privacy Act Officer; U.S... via the internet. Internet requests should be transmitted through the Board's Web site at www.nwtrb...

  8. 41 CFR 105-68.600 - How do suspension and debarment actions start?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How do suspension and debarment actions start? 105-68.600 Section 105-68.600 Public Contracts and Property Management Federal... Relating to Suspension and Debarment Actions § 105-68.600 How do suspension and debarment actions start...

  9. 41 CFR 105-74.100 - What does this part do?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What does this part do? 105-74.100 Section 105-74.100 Public Contracts and Property Management Federal Property Management... Administration 74-GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose and Coverage...

  10. 36 CFR 1212.105 - Does this part apply to me?

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Does this part apply to me? 1212.105 Section 1212.105 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION GENERAL RULES GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Purpose...

  11. 41 CFR 105-60.304 - Public information handbook and index.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Public information handbook and index. 105-60.304 Section 105-60.304 Public Contracts and Property Management Federal Property... index. GSA publishes a handbook for the public that identifies information regarding any matter...

  12. Localization of amylin-like immunoreactivity in melanocyte-stimulating hormone-containing cells of the pars intermedia but not those of the pars distalis in the axolotl (Ambystoma mexicanum) pituitary.

    Science.gov (United States)

    Suzuki, Hirohumi; Yamamoto, Toshiharu

    2016-04-01

    Immunohistochemical techniques were employed to investigate the distribution of amylin-like immunoreactivity in the axolotl (Ambystoma mexicanum) pituitary. Amylin-immunoreactive cells were observed in the pars intermedia, and these cells were found to be immunoreactive for α-melanocyte-stimulating hormone (αMSH) as well. In contrast, αMSH-immunoreactive cells in the pars distalis were immuno-negaitive for amylin. These light microscopic findings were confirmed by immunoelectron microscopy. Amylin-immunoreactive signals were located on the haloes of presumable secretory granules in association with αMSH-immunoreactive signals in the amylin-positive cells. However, in the pars distalis, the αMSH-positive cells did not contain amylin-immunoreactive secretory granules. Western blot analysis of axolotl pituitary extracts revealed the labeling of a protein band at approximately 10.5-kDa by the anti-rat amylin serum, which was not labeled by the anti-αMSH antibody. These findings indicate that amylin secreted from MSH-producing cells in the pars intermedia may modulate MSH secretion in an autocrine fashion and may participate in MSH functions such as fatty homeostasis together with MSH. Copyright © 2016 Elsevier GmbH. All rights reserved.

  13. Peptide-Based Optical uPAR Imaging for Surgery

    DEFF Research Database (Denmark)

    Juhl, Karina; Christensen, Anders; Persson, Morten

    2016-01-01

    Near infrared intra-operative optical imaging is an emerging technique with clear implications for improved cancer surgery by enabling a more distinct delineation of the tumor margins during resection. This modality has the potential to increase the number of patients having a curative radical...... tumor resection. In the present study, a new uPAR-targeted fluorescent probe was developed and the in vivo applicability was evaluated in a human xenograft mouse model. Most human carcinomas express high level of uPAR in the tumor-stromal interface of invasive lesions and uPAR is therefore considered...... an ideal target for intra-operative imaging. Conjugation of the flourophor indocyanine green (ICG) to the uPAR agonist (AE105) provides an optical imaging ligand with sufficiently high receptor affinity to allow for a specific receptor targeting in vivo. For in vivo testing, human glioblastoma xenograft...

  14. 10 CFR 1042.105 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Introduction § 1042.105 Definitions. As used in these Title... a condition to becoming a recipient of Federal financial assistance. Designated agency official... in this section. Federal financial assistance means any of the following, when authorized or extended...

  15. 41 CFR 105-50.401 - Reports submitted to the Congress.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Reports submitted to the Congress. 105-50.401 Section 105-50.401 Public Contracts and Property Management Federal Property... Congress. (a) The Administrator of General Services will furnish annually to the respective Committees on...

  16. 41 CFR 105-8.152 - Program accessibility: Assignment of space.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Program accessibility: Assignment of space. 105-8.152 Section 105-8.152 Public Contracts and Property Management Federal Property...-8.152 Program accessibility: Assignment of space. (a) When GSA assigns or reassigns space to an...

  17. Par and IR reflectance, transmittance, and absorptance of four crop canopies

    International Nuclear Information System (INIS)

    Wanjura, D.F.; Hatfield, J.L.

    1986-01-01

    Reflectance, transmittance and absorptance of electromagnetic radiation by cotton, soybeans, grain sorghum, and sunflower was measured at three growth stages in two wavebands (PAR: 0.4 to 0.7 pun and IR: 0.7 to 1.1 yim). As leaf area increased in each crop there were increases in IR reflectance and PAR absorptance and decreases in PAR reflectance and both PAR and IR transmittance. IR radiation was concentrated at the soil surface between rows by reflectance from the sides of canopies when crop cover was less than 80%. Across all crops one parameter, leaf overlap index, explained 81 and 71% of the PAR reflectance and another, crop cover, explained 86 and 94% of IR reflectance from rows and interrows, respectively. Attenuation of PAR radiation through the canopies of cotton and sunflower was similar (K = 0.62 and 0.67) but different from that of soybeans and grain sorghum (K = 0.46 and 0.43) which were the same

  18. C9.A/14 steelwork joints de poutres par plaque frontale : assemblages par gousset

    CERN Document Server

    2015-01-01

    Les Tables de résistances ultimes des assemblages boulonnés par plaque frontale et par gousset, complétées par une description des modèles de calcul et des exemples d’application, ont pour but de faciliter la tâche de l'ingénieur et du constructeur. Cette première partie C9.A/14 contient les chapitres suivants: - Joints de poutres par plaque frontale en acier S235 et S355 - Assemblages par gousset en acier S235 et S355 Les Tables contiennent des données relatives à la géométrie ainsi que les valeurs de calcul correspondantes des résistances ultimes des assemblages ; elles remplacent le chapitre « Assemblages par plaques frontales et boulons HR » des anciennes Tables C9.1 de 1983 / 2002. Le calcul de ces assemblages par plaque frontale est basé sur les hypothèses du modèle de la méthode des composants décrite dans la norme SN EN 1993-1-8. Les vérifications sont effectuées selon la norme SIA 263:2013. Les assemblages par gousset remplacent les assemblages par double cornière, (telle...

  19. 10 CFR 5.105 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... FINANCIAL ASSISTANCE Introduction § 5.105 Definitions. As used in these Title IX regulations, the term... approved by an official of the Federal agency that awards Federal financial assistance, or by a recipient.... Federal financial assistance means any of the following, when authorized or extended under a law...

  20. 33 CFR 127.105 - Layout and spacing of marine transfer area for LNG.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Layout and spacing of marine transfer area for LNG. 127.105 Section 127.105 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... AND LIQUEFIED HAZARDOUS GAS Waterfront Facilities Handling Liquefied Natural Gas § 127.105 Layout and...

  1. 41 CFR 105-72.300 - Purpose of financial and program management.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Purpose of financial and.../Financial and Program Management § 105-72.300 Purpose of financial and program management. Sections 105-72... Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General...

  2. Lumbar lordosis and pars interarticularis fractures: a case-control study

    Energy Technology Data Exchange (ETDEWEB)

    Bugg, William G.; Lewis, Mark; Juette, Arne; Cahir, John G.; Toms, Andoni P. [Cotman Centre, Norwich Radiology Academy, Norwich, Norfolk (United Kingdom)

    2012-07-15

    The aim of this study is to examine the relationship between lumbar lordosis and pars interarticularis fractures. In this retrospective case-control study we compare the angle of lumbar lordosis and the angle of the S1 vertebral endplate (as a measure of pelvic tilt) in patients with bilateral L5 pars interarticularis fractures with age- and sex-matched control cases with normal MRI examinations of the lumbar spine. Twenty-nine cases of bilateral L5 pars interarticularis fractures with matched control-cases were identified on MRI (16 male, 13 female, age 9-63 years). The angle of lordosis was measured between the inferior L4 and superior S1 vertebral endplates on a standing lateral lumbar spine radiograph for both groups. The mean angle of lordosis about the L5 vertebra was 36.9 (SD = 6.5 ) in the pars interarticularis fracture group, and 30.1 (SD = 6.4 ) in the control group. The difference between the two groups was significant (mean difference 6.8 , Student's t test: P < 0.001). The mean angle of sacral tilt measured was 122.2 (SD = 10.16 ) for controls and 136.4 (SD = 10.86 ) for patients with pars defects. The difference in the means of 14.2 was statistically significantly different (P < 0.0001). Sacral tilt represented by a steeply angled superior endplate of S1 is associated with a significantly increased angle of lordosis, between L4 and S1, and pars fractures at L5. Steep angulation of the first sacral vertebral segment maybe the predisposing biomechanical factor that leads to pincer-like impingement of the pars interarticularis and then spondylolysis. (orig.)

  3. 34 CFR 84.105 - Does this part apply to me?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Does this part apply to me? 84.105 Section 84.105 Education Office of the Secretary, Department of Education GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE... Education; or (2) A(n) ED awarding official. (See definitions of award and recipient in §§ 84.605 and 84.660...

  4. 41 CFR 105-71.132 - Equipment.

    Science.gov (United States)

    2010-07-01

    .... (4) When acquiring replacement equipment, the grantee or subgrantee may use the equipment to be... managing equipment (including replacement equipment), whether acquired in whole or in part with grant funds... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Equipment. 105-71.132...

  5. 28 CFR 105.11 - Individuals not requiring a security risk assessment.

    Science.gov (United States)

    2010-07-01

    ... requiring a security risk assessment. (a) Citizens and nationals of the United States. A citizen or national... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Individuals not requiring a security risk assessment. 105.11 Section 105.11 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CRIMINAL HISTORY...

  6. 30 CFR 210.105 - May I submit these production reports manually?

    Science.gov (United States)

    2010-07-01

    ... addressed to Minerals Management Service, P.O. Box 17110, Denver, Colorado 80217-0110; or (2) Special... 30 Mineral Resources 2 2010-07-01 2010-07-01 false May I submit these production reports manually? 210.105 Section 210.105 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR...

  7. 41 CFR 105-54.101 - Applicability.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Applicability. 105-54... consensus advice or recommendations. However, such a group would be covered by the Act when an agency accepts the group's deliberations as a source of consensus advice or recommendations; (i) A meeting of two...

  8. PARS risk charts: A 10-year study of risk assessment for cardiovascular diseases in Eastern Mediterranean Region.

    Directory of Open Access Journals (Sweden)

    Nizal Sarrafzadegan

    Full Text Available This study was designed to develop a risk assessment chart for the clinical management and prevention of the risk of cardiovascular disease (CVD in Iranian population, which is vital for developing national prevention programs. The Isfahan Cohort Study (ICS is a population-based prospective study of 6504 Iranian adults ≥35 years old, followed-up for ten years, from 2001 to 2010. Behavioral and cardiometabolic risk factors were examined every five years, while biennial follow-ups for the occurrence of the events was performed by phone calls or by verbal autopsy. Among these participants, 5432 (2784 women, 51.3% were CVD free at baseline examination and had at least one follow-up. Cox proportional hazard regression was used to predict the risk of ischemic CVD events, including sudden cardiac death due to unstable angina, myocardial infarction, and stroke. The model fit statistics such as area under the receiver-operating characteristic (AUROC, calibration chi-square and the overall bias were used to assess the model performance. We also tested the Framingham model for comparison. Seven hundred and five CVD events occurred during 49452.8 person-years of follow-up. The event probabilities were calculated and presented color-coded on each gender-specific PARS chart. The AUROC and Harrell's C indices were 0.74 (95% CI, 0.72-0.76 and 0.73, respectively. In the calibration, the Nam-D'Agostino χ2 was 10.82 (p = 0.29. The overall bias of the proposed model was 95.60%. PARS model was also internally validated using cross-validation. The Android app and the Web-based risk assessment tool were also developed as to have an impact on public health. In comparison, the refitted and recalibrated Framingham models, estimated the CVD incidence with the overall bias of 149.60% and 128.23% for men, and 222.70% and 176.07% for women, respectively. In conclusion, the PARS risk assessment chart is a simple, accurate, and well-calibrated tool for predicting a 10-year

  9. Permanent magnets prepared from Sm{sub 10.5}Fe{sub 88.5}Zr{sub 1.0}N{sub y} without homogenization

    Energy Technology Data Exchange (ETDEWEB)

    Gebel, B.; Kubis, M.; Mueller, K.-H. [Institut fuer Festkoerper- und Werkstofforschung Dresden e.V. (Germany). Inst. fuer Metallische Werkstoffe

    1997-10-01

    In as-cast Sm{sub 2}Fe{sub 17} the high amount of {alpha}-Fe caused by a peritectic reaction can be considerably reduced by a small addition of about 1 at% Zr. X-ray diffraction showed that as-cast Sm{sub 10.5}Fe{sub 88.5}Zr{sub 1.0} mainly consists of a phase with the Th{sub 2}Zn{sub 17}-type structure and SmFe{sub 3}. Non-homogenized Sm{sub 10.5}Fe{sub 88.5}Zr{sub 1.0} was milled and (i) annealed in vacuum or (ii) treated with a hydrogenation-disproportionation-desorp tion-recombination (HDDR) process. The annealed and subsequently nitrogenated powder is magnetically anisotropic and has a coercivity {mu}{sub 0J}H{sub C} up to 2.0 T and an energy product (BH){sub max} up to 136 kJ/m{sup 3}. HDDR-treated and nitrogenated powder is isotropic and exhibits values of {mu}{sub 0J}H{sub C} = 3.1 T and (BH){sub max} 103 kJ/m{sup 3}. Consequently, Sm{sub 10.5}Fe{sub 88.5}Zr{sub 1.0}N{sub y} (y {approx} 16) permanent magnets with very good properties can be prepared without the time-consuming homogenization procedure. (orig.). 11 refs.

  10. 28 CFR 105.25 - Authorized employer's responsibilities.

    Science.gov (United States)

    2010-07-01

    ... BACKGROUND CHECKS Private Security Officer Employment § 105.25 Authorized employer's responsibilities. An authorized employer is responsible for: (a) Executing and providing to the appropriate state agency the... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Authorized employer's responsibilities...

  11. Lumbar lordosis and pars interarticularis fractures: a case-control study

    International Nuclear Information System (INIS)

    Bugg, William G.; Lewis, Mark; Juette, Arne; Cahir, John G.; Toms, Andoni P.

    2012-01-01

    The aim of this study is to examine the relationship between lumbar lordosis and pars interarticularis fractures. In this retrospective case-control study we compare the angle of lumbar lordosis and the angle of the S1 vertebral endplate (as a measure of pelvic tilt) in patients with bilateral L5 pars interarticularis fractures with age- and sex-matched control cases with normal MRI examinations of the lumbar spine. Twenty-nine cases of bilateral L5 pars interarticularis fractures with matched control-cases were identified on MRI (16 male, 13 female, age 9-63 years). The angle of lordosis was measured between the inferior L4 and superior S1 vertebral endplates on a standing lateral lumbar spine radiograph for both groups. The mean angle of lordosis about the L5 vertebra was 36.9 (SD = 6.5 ) in the pars interarticularis fracture group, and 30.1 (SD = 6.4 ) in the control group. The difference between the two groups was significant (mean difference 6.8 , Student's t test: P < 0.001). The mean angle of sacral tilt measured was 122.2 (SD = 10.16 ) for controls and 136.4 (SD = 10.86 ) for patients with pars defects. The difference in the means of 14.2 was statistically significantly different (P < 0.0001). Sacral tilt represented by a steeply angled superior endplate of S1 is associated with a significantly increased angle of lordosis, between L4 and S1, and pars fractures at L5. Steep angulation of the first sacral vertebral segment maybe the predisposing biomechanical factor that leads to pincer-like impingement of the pars interarticularis and then spondylolysis. (orig.)

  12. Lumbar lordosis and pars interarticularis fractures: a case-control study

    Energy Technology Data Exchange (ETDEWEB)

    Bugg, William G; Lewis, Mark; Juette, Arne; Cahir, John G; Toms, Andoni P [Cotman Centre, Norwich Radiology Academy, Norwich, Norfolk (United Kingdom)

    2012-07-15

    The aim of this study is to examine the relationship between lumbar lordosis and pars interarticularis fractures. In this retrospective case-control study we compare the angle of lumbar lordosis and the angle of the S1 vertebral endplate (as a measure of pelvic tilt) in patients with bilateral L5 pars interarticularis fractures with age- and sex-matched control cases with normal MRI examinations of the lumbar spine. Twenty-nine cases of bilateral L5 pars interarticularis fractures with matched control-cases were identified on MRI (16 male, 13 female, age 9-63 years). The angle of lordosis was measured between the inferior L4 and superior S1 vertebral endplates on a standing lateral lumbar spine radiograph for both groups. The mean angle of lordosis about the L5 vertebra was 36.9 (SD = 6.5 ) in the pars interarticularis fracture group, and 30.1 (SD = 6.4 ) in the control group. The difference between the two groups was significant (mean difference 6.8 , Student's t test: P < 0.001). The mean angle of sacral tilt measured was 122.2 (SD = 10.16 ) for controls and 136.4 (SD = 10.86 ) for patients with pars defects. The difference in the means of 14.2 was statistically significantly different (P < 0.0001). Sacral tilt represented by a steeply angled superior endplate of S1 is associated with a significantly increased angle of lordosis, between L4 and S1, and pars fractures at L5. Steep angulation of the first sacral vertebral segment maybe the predisposing biomechanical factor that leads to pincer-like impingement of the pars interarticularis and then spondylolysis. (orig.)

  13. Alimentation animale et valeur nutritionnelle induite sur les produits dérivés consommés par l’homme : Les lipides sont-ils principalement concernés ?

    Directory of Open Access Journals (Sweden)

    Bourre Jean-Marie

    2003-09-01

    sous contrôle génétique. En revanche, la nature des acides gras des triglycérides de réserve (trouvés en quantité plus ou moins importante selon les localisations anatomiques c’est-à-dire les morceaux de boucherie peut varier notablement en fonction de la nourriture reçue par les animaux. En les contrôlant, il est possible de contribuer à un meilleur état sanitaire des consommateurs. Les conséquences (qualitatives et quantitatives des modifications de la composition de l’alimentation animale sur la valeur des produits dérivés consommés par l’homme sont plus amples chez les mono-gastriques que chez les poly-gastriques. Car, par exemple, les bactéries intestinales hydrogénantes de ces derniers transforment en acides gras saturés une fraction notable des acides gras poly-insaturés présents dans leur alimentation, leur faisant par conséquent perdre leur intérêt biologique. Ainsi, dans les meilleures conditions, en nourrissant par exemple les animaux avec des graines de lin ou de colza, la teneur en acide alpha-linolénique est multipliée par environ 2 dans la viande de bœuf, par 6 dans celle de porc, par 10 dans le poulet, par 40 dans les œufs. En nourrissant les animaux avec des extraits de poissons ou d’algues (huiles, la quantité de DHA (acide cervonique, 22:6ω3 est multipliée par 2 dans la viande de bœuf, par 7 dans le poulet, par 6 dans les œufs, par 20 dans le poisson (saumon. Pour obtenir de tels résultats, il ne s’agit que de respecter la physiologie des animaux, ce qui était fréquemment le cas avec les méthodes traditionnelles. Il convient de mettre l’accent sur les poissons, dont la valeur nutritionnelle pour l’homme en termes de lipides (déterminée par la quantité d’acides gras oméga-3 peut varier considérablement selon la nature des graisses avec lesquelles les animaux sont alimentés. L’objectif de prévention de certains aspects des maladies cardio-vasculaires (et d’autres pathologies peut être

  14. The 105 month Swift-BAT data release

    Science.gov (United States)

    Oh, Kyuseok; Koss, Michael; Markwardt, Craig B.; Schawinski, Kevin; Baumgartner, Wayne H.; Barthelmy, Scott D.; Cenko, Bradley; Gehrels, Neil; Mushotzky, Richard; Petulante, Abigail; Ricci, Claudio; Lien, Amy; Trakhtenbrot, Benny; NASA GSFC Swift BAT team, BAT AGN Spectroscopic Survey (BASS)

    2018-01-01

    We present a new catalog of hard X-ray sources detected in the first 105 months of observations with the Burst Alert Telescope (BAT) on board the Swift observatory. The 105 month Swift-BAT survey is a uniform hard X-ray all-sky survey with a sensitivity of 8.40×10-12 erg s-1 cm-2 over 90% of the sky and 7.24×10-12 erg s-1 cm-2 over 50% of the sky in the 14‑195 keV band. The Swift-BAT 105 month catalog provides 1632 (422 new detections) hard X-ray sources in the 14 ‑ 195 keV band above the 4.8σ significance level. Adding to the previously known hard X-ray sources, 34% (144/422) of the new detections are identified as Seyfert AGN in nearby galaxies (z BAT catalog, we release eight-channel spectra and monthly sampled light curves for each object in the online journal and at the Swift-BAT 105 month Web site.

  15. Novas determinações dos parâmetros atmosféricos das estrelas anãs brancas DA

    Science.gov (United States)

    Giovannini, O.; Costa, A. F. M.; Kepler, S. O.

    2003-08-01

    s temos selecionado uma amostra de estrelas anãs brancas DA (atmosfera de hidrogênio) a partir dos índices de Strömgren cujos valores estão próximos a região de instabilidade das estrelas anãs brancas DA variáveis, as chamadas estrelas DAV ou ZZ Ceti. O objetivo é determinar os parâmetros fundamentais (temperatura efetiva, Teff, aceleração da gravidade, log g, e massa) destas estrelas para verificar quais os parâmetros estelares estão envolvidos com o mecanismo de pulsação das estrelas DAV. Nós obtemos, até agora, mais de 120 espectros óticos de estrelas DA. Entre as estrelas selecionadas há 20 estrelas variáveis (DAV). Assim, podemos verificar se existem ou não estrelas não variáveis dentro da faixa de instabilidade das estrelas ZZ Ceti. Neste trabalho nós apresentamos a determinação dos parâmetros atmosféricos (temperatura efetiva, Teff, e aceleração da gravidade, log g) das estrelas anãs brancas DA usando os novos modelos de atmosfera ML2/a = 0.6. Estes modelos têm sido utilizados recentemente por fornecerem uma excelente consistência interna na determinação das temperaturas nas regiões do ultra-violeta e ótico. Os parâmetros atmosféricos são determinados espectroscopicamente através da comparação do fluxo de energia das linhas de Balmer (Hb à H9) entre os espectros observados e sintéticos (gerados pelos modelos de atmosfera). As temperaturas obtidas com os novos modelos são, em geral, menores (~ 1000 K menos) que as temperaturas determinadas anteriormente, com modelos ML1. Os valores de log g não mudaram significativamente (menos de 10%). A faixa de instabilidade das DAVs está entre 11000 e 13000 K, consistente com dados de outros autores.

  16. 47 CFR 65.105 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Discovery. 65.105 Section 65.105... OF RETURN PRESCRIPTION PROCEDURES AND METHODOLOGIES Procedures § 65.105 Discovery. (a) Participants... evidence. (c) Discovery requests pursuant to § 65.105(b), including written interrogatories, shall be filed...

  17. 41 CFR 105-74.230 - How and when must I identify workplaces?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How and when must I identify workplaces? 105-74.230 Section 105-74.230 Public Contracts and Property Management Federal... employees in each local unemployment office, performers in concert halls or radio studios). (c) If you...

  18. 41 CFR 105-70.040 - Stays ordered by the Department of Justice.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Stays ordered by the Department of Justice. 105-70.040 Section 105-70.040 Public Contracts and Property Management Federal... Stays ordered by the Department of Justice. If at any time the Attorney General or an Assistant Attorney...

  19. Variation de la composition de nanoparticules de 1-10 nm obtenues par séparation de phase dans un verre de silice

    OpenAIRE

    Blanc , W; Francois-Saint-Cyr , H; Martin , I; Lecoustumer , P; Hombourger , C; R. Neuville , D.; Larson , D.J.; Prosa , T.J.; Guillermier , C

    2014-01-01

    National audience; Les verres contenant des nanoparticules ont de nombreuses applications industrielles, notamment grâce à leurs excellentes propriétés thermo-mécaniques [1]. Ils présentent aussi un intérêt pour les propriétés optiques. En effet, l'encapsulation d'ions luminescents (ions de terre rare par exemple) dans des nanoparticules entraînent de nouvelles propriétés de luminescence qui n'existeraient pas dans le verre hôte (bande d'émission élargie, efficacité quantique augmentée, etc) ...

  20. uPAR Targeted Radionuclide Therapy with 177Lu-DOTA-AE105 Inhibits Dissemination of Metastatic Prostate Cancer

    DEFF Research Database (Denmark)

    Persson, Morten; Juhl, Karina; Rasmussen, Palle

    2014-01-01

    The urokinase-type plasminogen activator receptor (uPAR) is implicated in cancer invasion and metastatic development in prostate cancer and provides therefore an attractive molecular target for both imaging and therapy. In this study, we provide the first in vivo data on an antimetastatic effect...... of uPAR radionuclide targeted therapy in such lesions and show the potential of uPAR positron emission tomography (PET) imaging for identifying small foci of metastatic cells in a mouse model of disseminating human prostate cancer. Two radiolabeled ligands were generated in high purity and specific...... value of 100 nM in a competitive binding experiment. In vivo, uPAR targeted radionuclide therapy significantly reduced the number of metastatic lesions in the disseminated metastatic prostate cancer model, when compared to vehicle and nontargeted 177Lu groups (p

  1. Metazoos parásitos de la mojarrilla Stellifer minor (Tschudi (Osteichthyes, Sciaenidae capturados por pesquería artesanal en Chorrillos, Lima, Perú Metazoan parasites of the minor stardrum, Stellifer minor (Tschudi (Osteichthyes, Sciaenidae, caught by artisanal fishery on Chorrillos, Lima, Peru

    Directory of Open Access Journals (Sweden)

    José Iannacone

    2004-12-01

    Full Text Available Se investigaron algunos componentes comunitarios de la parasitofauna de 105 ejemplares de Stellifer minor (Tschudi, 1844 colectados del Terminal Pesquero de Chorrillos, Lima, Perú, entre el mayo y octubre de 1998 y necropsiados para estudiar sus comunidades parasitarias. De los peces colectados, 71 fueron machos y 34 hembras. Los peces mostraron una longitud estándar entre 10,20-20,50 cm (promedio = 15,50 ± 1,65. Los parásitos metazoos fueron colectados y censados empleando las técnicas convencionales. Se colectaron un total de 3483 especimenes durante todo el muestreo, con una abundancia media total de 33,17 (3-122. El promedio de la riqueza de especies de parásitos fue 1,9 (1-4. Un hospedero no presentó ningún parásito. 20 hospederos (19,04% mostraron infección con un solo parásito, 77 (73,33% y 7 (6,66% tuvieron una infección múltiple, con 2 y 3 especies de parásitos, respectivamente. Se encontraron cinco parásitos: Rhamnocercus oliveri Luque & Iannacone, 1991 y R. stelliferi Luque & Iannacone, 1991 (Monogenea (prevalencia = 98,09%; intensidad media = 28,85; abundancia media = 28,58, Clavellotis dilatata (Kroyer, 1863 (Copepoda (prevalencia = 2,85%; intensidad media = 1; abundancia media = 0,02, Helicometra fasciata (Rudolphi, 1819 (Digenea (prevalencia = 79,04%; intensidad media = 5,77; abundancia media = 4,56 y Procamallanus (Spirocamallanus pereirai Annereaux, 1946 (Nematoda (prevalencia = 4,76%; intensidad media = 1,6; abundancia media = 0,07. Se encontró efecto del sexo en la intensidad y abundancia media de Infección de Rhamnocercus Monaco, Wood & Mizelle, 1954 y también efecto del sexo con la abundancia media de infección con H. fasciata. La diversidad media de las infracomunidades según el índice de Shannon-Weaver de S. minor fue (H' = 0,11 y el índice de Simpson (C = 0,98. Se compararon los resultados obtenidos con la estructura comunitaria parasitaria registrada en la década anterior en S. minor en la misma

  2. 41 CFR 105-64.105 - When may Social Security Numbers (SSNs) be collected?

    Science.gov (United States)

    2010-07-01

    ...-64.105 When may Social Security Numbers (SSNs) be collected? (a) Statutory or regulatory authority must exist for collecting Social Security Numbers for record systems that use the SSNs as a method of... collect Social Security Numbers. (b) In compliance with OMB M-07-16 (Safeguarding Against and Responding...

  3. 41 CFR 105-68.340 - If I disclose unfavorable information required under § 105-68.335, will I be prevented from...

    Science.gov (United States)

    2010-07-01

    ... Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General Services... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false If I disclose unfavorable information required under § 105-68.335, will I be prevented from participating in the...

  4. Pierre Vilar Frontinhan 1906 - París 2003

    Directory of Open Access Journals (Sweden)

    Pablo Rodríguez

    2003-01-01

    Full Text Available En el pasado mes de agosto falleció en París el historiador y maestro de tantas generaciones Pierre Vilar. Aunque había mantenido una intensa actividad de reflexión sobre los sucesos contemporáneos, ésta se vio afectada en 1991 luego que una grave enfermedad le negó la visión. Fue entonces cuando decidió con la ayuda de Rosa Congost escribir sus reflexiones y recuerdos, especie de memoria de juventud. Pensar Históricamente (Barcelona: Editorial Crítica, 1997, el libro que reúne estos ejercicios, es una obra de sumo interés para conocer la infancia, adolescencia y juventud de este connotado historiador.

  5. Viaje póstumo a París del Faraón Ramsés II

    Directory of Open Access Journals (Sweden)

    Esteban Llagostera

    2010-01-01

    Full Text Available Por primera vez en la historia, un faraón egipcio viaja al extranjero. Su momia, fue trasladada a París, para «curarla» de las múltiples invasiones de bacterias, insectos necrófagos, microbios y hongos de los que estaba invadido, además de múltiples fracturas. E igualmente, para diagnosticar las causas de su muerte. El traslado de El Cairo a París y regreso, se realizó con un avión militar francés. Egipto, notificó a Israel este vuelo extraordinario, para evitar cualquier problema que pudiera surgir, en aquella zona tan conflictiva de Oriente Medio. En cuanto el avión penetro en el espacio aéreo francés, dos reactores militares le dieron escolta hasta el aeropuerto de Le Bourget-París, donde se le rindieron honores de Jefe de Estado. Toda Francia se puso a disposición de Ramsés el Grande. Mme. Desroches- Noblecourt, Inspectora General a Perpetuidad de los Museos Estatales de Francia, no lo abandonó ni un momento y voló con él desde Heliopolis hasta París y su posterior regreso a El Cairo.When French scientists informed Mme. Desroches-Noblecourt, Inspector General of National Museums, of the poor state of preservation of the mummy of pharaoh Ramesses II (he suffered from bacteria, necrophagus insects, fungus, etc., she immediately informed the President of France, who made a quick trip to inform the Egyptian President about the news. Giscard d’Estaing suggested taking the mummy to Paris in a special plane. Due to the political situation of the time and because Ramesses II would be travelling in a military plane, Egypt informed Israel about the special conditions surrounding this extraordinary flight. This was to be the first time in History that an Egyptian pharaoh «travelled» to a foreign country. The plane departed from Cairo’s Heliopolis Airport where the royal passenger was treated to the honours of a living king. The date was September 26th, 1976. The moment the plane entered French air space; two air force

  6. 41 CFR 102-117.105 - What does best value mean when routing a shipment?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What does best value mean when routing a shipment? 102-117.105 Section 102-117.105 Public Contracts and Property Management... 117-TRANSPORTATION MANAGEMENT Business Rules To Consider Before Shipping Freight or Household Goods...

  7. 41 CFR 105-8.150-4 - Transition plan.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Transition plan. 105-8... Transition plan. In the event that structural changes to facilities will be undertaken to achieve program accessibility, the agency shall develop, by March 9, 1992; the transition plan setting forth the steps necessary...

  8. 41 CFR 105-53.143 - Information Resources Management Service.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Information Resources... FUNCTIONS Central Offices § 105-53.143 Information Resources Management Service. (a) Creation and authority. The Information Resources Management Service (IRMS), headed by the Commissioner, Information Resources...

  9. 45 CFR 1230.105 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... services in the private sector. (o) Recipient includes all contractors, subcontractors at any tier, and... 45 Public Welfare 4 2010-10-01 2010-10-01 false Definitions. 1230.105 Section 1230.105 Public... NEW RESTRICTIONS ON LOBBYING General § 1230.105 Definitions. For purposes of this part: (a) Agency, as...

  10. 41 CFR 105-74.205 - What must I include in my drug-free workplace statement?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What must I include in my drug-free workplace statement? 105-74.205 Section 105-74.205 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION...

  11. 41 CFR 105-74.215 - What must I include in my drug-free awareness program?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What must I include in my drug-free awareness program? 105-74.215 Section 105-74.215 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION...

  12. 41 CFR 105-74.210 - To whom must I distribute my drug-free workplace statement?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false To whom must I distribute my drug-free workplace statement? 105-74.210 Section 105-74.210 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION...

  13. 30 CFR 816.105 - Backfilling and grading: Thick overburden.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Backfilling and grading: Thick overburden. 816...-SURFACE MINING ACTIVITIES § 816.105 Backfilling and grading: Thick overburden. (a) Definition. Thick... surrounding terrain. (b) Performance standards. Where thick overburden occurs within the permit area, the...

  14. ELIMINATION DU 4-CHLOROPHÉNOL PAR DES PROCÉDÉS D’OXYDATION AVANCÉE

    OpenAIRE

    BENBACHIR, Hayet

    2010-01-01

    Ce mémoire est consacré à l'étude de l'applicabilité des procédés d’oxydation avancée pour le traitement des eaux contaminées par des polluants organiques. Dans cette étude, nous avons mis en évidence que la cinétique de dégradation et les rendements de minéralisation de 4-Chlorophénol pouvaient être significativement augmentés, par variation des différents paramètres expérimentaux (pH, le rapport R, la concentration du polluant…). Nous avons également déterminé au cours de ce ...

  15. Positron emission tomography imaging of CD105 expression in a rat myocardial infarction model with (64)Cu-NOTA-TRC105.

    Science.gov (United States)

    Orbay, Hakan; Zhang, Yin; Valdovinos, Hector F; Song, Guoqing; Hernandez, Reinier; Theuer, Charles P; Hacker, Timothy A; Nickles, Robert J; Cai, Weibo

    2013-01-01

    Biological changes following myocardial infarction (MI) lead to increased secretion of angiogenic factors that subsequently stimulate the formation of new blood vessels as a compensatory mechanism to reverse ischemia. The goal of this study was to assess the role of CD105 expression during MI-induced angiogenesis by positron emission tomography (PET) imaging using (64)Cu-labeled TRC105, an anti-CD105 monoclonal antibody. MI was induced by ligation of the left anterior descending (LAD) artery in female rats. Echocardiography and (18)F-fluoro-2-deoxy-D-glucose ((18)F-FDG) PET scans were performed on post-operative day 3 to confirm the presence of MI in the infarct group and intact heart in the sham group, respectively. Ischemia-induced angiogenesis was non-invasively monitored with (64)Cu-NOTA-TRC105 (an extensively validated PET tracer in our previous studies) PET on post-operative days 3, 10, and 17. Tracer uptake in the infarct zone was highest on day 3 following MI, which was significantly higher than that in the sham group (1.41 ± 0.45 %ID/g vs 0.57 ± 0.07 %ID/g; n=3, p<0.05). Subsequently, tracer uptake in the infarct zone decreased over time to the background level on day 17, whereas tracer uptake in the heart of sham rats remained low at all time points examined. Histopathology documented increased CD105 expression following MI, which corroborated in vivo findings. This study indicated that PET imaging of CD105 can be a useful tool for MI-related research, which can potentially improve MI patient management in the future upon clinical translation of the optimized PET tracers.

  16. Inclusão do equivalente energético do lactato na regressão VO2-intensidade em corrida horizontal e inclinada (10,5%

    Directory of Open Access Journals (Sweden)

    Victor Machado REIS

    Full Text Available Resumo O estudo teve por objetivo analisar o efeito da adição do equivalente energético do lactato sanguíneo com a medida de VO2 durante a corrida em esteira horizontal (0% e inclinada (10,5%, como forma de estimativa do custo energético da corrida. Treze corredores de meia e longa distância (idade 28,1 ± 4,2 anos; estatura 1,75 ± 0,07 m; massa corporal 65,2 ± 4,9 kg; VO2max 70,3 ± 4,9 ml·kg-1·min-1 cumpriram dois testes em esteira rolante (0% e 10,5% que incluíram vários estágios em intensidade constante. Foram calculadas para cada atleta as regressões VO2-velocidade, bem como regressões alternativas com a adição de um equivalente energético de 3 ml O2 Eq·kg-1·mM [La-] às medições de VO2. Não se verificou interação significativa entre a adição do equivalente do lactato e a inclinação da esteira. A ANOVA indicou um efeito significativo da adição do equivalente do lactato na inclinação da reta de regressão e na estimativa do custo energético. Os tamanhos do efeito obtidos indicam que este efeito é mais forte na corrida horizontal. Estes resultados sugerem que em testes laboratoriais com corredores treinados se deverá considerar a adição dos valores de VO2 com os equivalentes energéticos do lactato.

  17. 41 CFR 105-53.133 - Information Security Oversight Office.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Information Security... FUNCTIONS Central Offices § 105-53.133 Information Security Oversight Office. (a) Creation and authority. The Information Security Oversight Office (ISOO), headed by the Director of ISOO, who is appointed by...

  18. 49 CFR 236.105 - Electric lock.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Electric lock. 236.105 Section 236.105 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION...: All Systems Inspections and Tests; All Systems § 236.105 Electric lock. Electric lock, except forced...

  19. 41 CFR 105-53.142 - Office of Public Affairs.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Office of Public Affairs... Central Offices § 105-53.142 Office of Public Affairs. The Office of Public Affairs, headed by the Associate Administrator for Public Affairs, is responsible for the planning, implementation, and...

  20. 49 CFR 234.105 - Activation failure.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Activation failure. 234.105 Section 234.105... of Warning System Malfunction § 234.105 Activation failure. Upon receipt of a credible report of warning system malfunction involving an activation failure, a railroad having maintenance responsibility...

  1. 41 CFR 105-50.202-7 - Technical information and advice.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Technical information... Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 50-PROVISION OF SPECIAL... Services Administration § 105-50.202-7 Technical information and advice. GSA will provide technical...

  2. 41 CFR 109-39.105 - Discontinuance or curtailment of service.

    Science.gov (United States)

    2010-07-01

    ... AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 39-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.1-Establishment, Modification, and Discontinuance of Interagency Fleet Management Systems § 109-39.105 Discontinuance or... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Discontinuance or...

  3. 68Ga-labeling and in vivo evaluation of a uPAR binding DOTA- and NODAGA-conjugated peptide for PET imaging of invasive cancers

    DEFF Research Database (Denmark)

    Persson, Morten; Madsen, Jacob; Østergaard, Søren

    2012-01-01

    , uPAR binding affinity and cell uptake were determined. To characterize the in vivo properties, dynamic microPET imaging was carried out in nude mice bearing human glioma U87MG tumor xenograft. RESULTS: In vitro experiments revealed uPAR binding affinities in the lower nM range for both conjugated......-AE105-NH(2) was observed. Good stability in phosphate-buffered saline and mouse plasma was observed. High cell uptake was found for both tracers in U87MG tumor cells. Dynamic microPET imaging demonstrated good tumor-to-background ratio for both tracers. Tumor uptake was 2.1% ID/g and 1.3% ID/g 30 min...... positron emission tomography (PET) in human cancer xenograft mice models. Here we introduce (68)Ga-DOTA-AE105-NH(2) and (68)Ga-NODAGA-AE105-NH(2) and evaluate their imaging properties using small-animal PET. METHODS: Synthesis of DOTA-AE105-NH(2) and NODAGA-AE105-NH(2) was based on solid-phase peptide...

  4. 29 CFR 825.105 - Counting employees for determining coverage.

    Science.gov (United States)

    2010-07-01

    ... limitations of the employer-employee relationship under the Act; and that determination of the relation cannot... later return to active employment. If there is no employer/employee relationship (as when an employee is... 29 Labor 3 2010-07-01 2010-07-01 false Counting employees for determining coverage. 825.105...

  5. Efecto de los parámetros de procesamiento sobre las características cristalinas de la solución sólida Y(CoxMn1-xO3, x=0.6, 0.7

    Directory of Open Access Journals (Sweden)

    Fernández, J. F.

    2002-02-01

    Full Text Available The preparation and crystalline features of perovskite solid solution Y(CoxMn1-xO3, x=0.6, 0.7, belonging to the Co-rich region of the pseudobinary system YMnO3-YCoO3 have been studied. Dilatometric essays performed under different atmospheres have been carried out for determining the best conditions to obtain single-phase samples. Influence of the thermal cycle and of the sintering density on the appearance of secondary phases has been also established. Firing under O2 atmosphere favours the formation of the pure perovskite. The cooling rate plays an important role for inhibiting the formation of secondary phases. All the crystalline parameters depend ultimately on the final density of the polycrystalline bodies.Se han estudiado la preparación y las características cristalinas de la solución sólida Y(CoxMn1-xO3, x=0.6, 0.7, con estructura de tipo perovsquita, perteneciente a la región rica en Co del sistema seudobinario YMnO3-YCoO3. Se han llevado a cabo ensayos dilatométricos bajo diferentes atmósferas para determinar las mejores condiciones para obtener cerámicas monofásicas. Se ha establecido igualmente la influencia del ciclo térmico y de la densidad de sinterizado sobre la aparición de fases secundarias. La sinterización en oxígeno favorece la formación de la perovsquita pura. La velocidad de enfriamiento juega un importante papel sobre la inhibición de la formación de fases secundarias. Todos los parámetros cristalinos dependen finalmente de la densidad final de los materiales cerámicos.

  6. 10 CFR 1015.105 - Form of payment.

    Science.gov (United States)

    2010-01-01

    ... DEPARTMENT OF ENERGY (GENERAL PROVISIONS) COLLECTION OF CLAIMS OWED THE UNITED STATES General § 1015.105 Form of payment. Claims may be paid in the form of money or, when a contractual basis exists, the Government may demand the return of specific property or the performance of specific services. ...

  7. 41 CFR 105-68.455 - What may I do if a lower tier participant fails to disclose the information required under § 105...

    Science.gov (United States)

    2010-07-01

    ... Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General Services... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What may I do if a lower tier participant fails to disclose the information required under § 105-68.355 to the next higher tier...

  8. 46 CFR 133.105 - Survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft. 133.105 Section 133.105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OFFSHORE SUPPLY VESSELS LIFESAVING SYSTEMS Requirements for All OSVs § 133.105 Survival craft. (a) Each survival craft must be approved and equipped as...

  9. 41 CFR 105-72.301 - Standards for financial management systems.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Standards for financial... Management § 105-72.301 Standards for financial management systems. (a) Federal awarding agencies shall... practical. (b) Recipients' financial management systems shall provide for the following. (1) Accurate...

  10. 41 CFR 105-72.505 - Cost and price analysis.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Cost and price analysis... § 105-72.505 Cost and price analysis. Some form of cost or price analysis shall be made and documented in the procurement files in connection with every procurement action. Price analysis may be...

  11. ParABS system in chromosome partitioning in the bacterium Myxococcus xanthus.

    Directory of Open Access Journals (Sweden)

    Antonio A Iniesta

    Full Text Available Chromosome segregation is an essential cellular function in eukaryotic and prokaryotic cells. The ParABS system is a fundamental player for a mitosis-like process in chromosome partitioning in many bacterial species. This work shows that the social bacterium Myxococcus xanthus also uses the ParABS system for chromosome segregation. Its large prokaryotic genome of 9.1 Mb contains 22 parS sequences near the origin of replication, and it is shown here that M. xanthus ParB binds preferentially to a consensus parS sequence in vitro. ParB and ParA are essential for cell viability in M. xanthus as in Caulobacter crescentus, but unlike in many other bacteria. Absence of ParB results in anucleate cells, chromosome segregation defects and loss of viability. Analysis of ParA subcellular localization shows that it clusters at the poles in all cells, and in some, in the DNA-free cell division plane between two chromosomal DNA masses. This ParA localization pattern depends on ParB but not on FtsZ. ParB inhibits the nonspecific interaction of ParA with DNA, and ParA colocalizes with chromosomal DNA only when ParB is depleted. The subcellular localization of ParB suggests a single ParB-parS complex localized at the edge of the nucleoid, next to a polar ParA cluster, with a second ParB-parS complex migrating after the replication of parS takes place to the opposite nucleoid edge, next to the other polar ParA cluster.

  12. 49 CFR 1572.105 - Immigration status.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Immigration status. 1572.105 Section 1572.105... ASSESSMENTS Standards for Security Threat Assessments § 1572.105 Immigration status. (a) An individual... to an order of removal under the immigration laws of the United States is not eligible to apply for a...

  13. La prise en compte inaboutie des droits et libertés fondamentaux par le droit constitutionnel

    OpenAIRE

    Magnon , Xavier

    2016-01-01

    International audience; Difficile de ne pas concéder un véritable désarroi face au sujet proposé 1 : la prise en compte inaboutie des droits et libertés fondamentaux par le droit constitutionnel. Un désarroi tiré de ce que, à titre personnel, et selon une première approche intuitive que l'on peut avoir du sujet, jamais la question de l'existence de lacunes ou de prise en compte inaboutie des droits et libertés par le droit constitutionnel formel ne s'était posée. Ce manque de réflexivité invi...

  14. Peptide-derivatized SB105-A10 dendrimer inhibits the infectivity of R5 and X4 HIV-1 strains in primary PBMCs and cervicovaginal histocultures.

    Directory of Open Access Journals (Sweden)

    Isabella Bon

    Full Text Available Peptide dendrimers are a class of molecules that exhibit a large array of biological effects including antiviral activity. In this report, we analyzed the antiviral activity of the peptide-derivatized SB105-A10 dendrimer, which is a tetra-branched dendrimer synthetized on a lysine core, in activated peripheral blood mononuclear cells (PBMCs that were challenged with reference and wild-type human immunodeficiency virus type 1 (HIV-1 strains. SB105-A10 inhibited infections by HIV-1 X4 and R5 strains, interfering with the early phases of the viral replication cycle. SB105-A10 targets heparan sulfate proteoglycans (HSPGs and, importantly, the surface plasmon resonance (SPR assay revealed that SB105-A10 strongly binds gp41 and gp120, most likely preventing HIV-1 attachment/entry through multiple mechanisms. Interestingly, the antiviral activity of SB105-A10 was also detectable in an organ-like structure of human cervicovaginal tissue, in which SB105-A10 inhibited the HIV-1ada R5 strain infection without altering the tissue viability. These results demonstrated the strong antiviral activity of SB105-A10 and suggest a potential microbicide use of this dendrimer to prevent the heterosexual transmission of HIV-1.

  15. 41 CFR 105-68.365 - What must I do if I learn of information required under § 105-68.355 after entering into a...

    Science.gov (United States)

    2010-07-01

    ... Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What must I do if I learn of information required under § 105-68.355 after entering into a covered transaction with a...

  16. 47 CFR 78.105 - Antenna systems.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Antenna systems. 78.105 Section 78.105... SERVICE Technical Regulations § 78.105 Antenna systems. (a) For fixed stations operating in the 12.7-13.2... planes. (2) New periscope antenna systems will be authorized upon a certification that the radiation, in...

  17. 40 CFR 1060.105 - What diurnal requirements apply for equipment?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false What diurnal requirements apply for... EQUIPMENT Emission Standards and Related Requirements § 1060.105 What diurnal requirements apply for... for controlling diurnal emissions: (1) If you are subject to both running loss and diurnal emission...

  18. 41 CFR 105-56.027 - Centralized salary offset computer match.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Centralized salary... Services Administration 56-SALARY OFFSET FOR INDEBTEDNESS OF FEDERAL EMPLOYEES TO THE UNITED STATES Centralized Salary Offset (CSO) Procedures-GSA as Paying Agency § 105-56.027 Centralized salary offset...

  19. 41 CFR 105-56.017 - Centralized salary offset computer match.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Centralized salary... Services Administration 56-SALARY OFFSET FOR INDEBTEDNESS OF FEDERAL EMPLOYEES TO THE UNITED STATES Centralized Salary Offset (CSO) Procedures-GSA as Creditor Agency § 105-56.017 Centralized salary offset...

  20. 47 CFR 25.105-25.108 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false [Reserved] 25.105-25.108 Section 25.105-25.108 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES SATELLITE COMMUNICATIONS General §§ 25.105-25.108 [Reserved] ...

  1. Analysis of ParB-centromere interactions by multiplex SPR imaging reveals specific patterns for binding ParB in six centromeres of Burkholderiales chromosomes and plasmids.

    Science.gov (United States)

    Pillet, Flavien; Passot, Fanny Marie; Pasta, Franck; Anton Leberre, Véronique; Bouet, Jean-Yves

    2017-01-01

    Bacterial centromeres-also called parS, are cis-acting DNA sequences which, together with the proteins ParA and ParB, are involved in the segregation of chromosomes and plasmids. The specific binding of ParB to parS nucleates the assembly of a large ParB/DNA complex from which ParA-the motor protein, segregates the sister replicons. Closely related families of partition systems, called Bsr, were identified on the chromosomes and large plasmids of the multi-chromosomal bacterium Burkholderia cenocepacia and other species from the order Burkholeriales. The centromeres of the Bsr partition families are 16 bp palindromes, displaying similar base compositions, notably a central CG dinucleotide. Despite centromeres bind the cognate ParB with a narrow specificity, weak ParB-parS non cognate interactions were nevertheless detected between few Bsr partition systems of replicons not belonging to the same genome. These observations suggested that Bsr partition systems could have a common ancestry but that evolution mostly erased the possibilities of cross-reactions between them, in particular to prevent replicon incompatibility. To detect novel similarities between Bsr partition systems, we have analyzed the binding of six Bsr parS sequences and a wide collection of modified derivatives, to their cognate ParB. The study was carried out by Surface Plasmon Resonance imaging (SPRi) mulitplex analysis enabling a systematic survey of each nucleotide position within the centromere. We found that in each parS some positions could be changed while maintaining binding to ParB. Each centromere displays its own pattern of changes, but some positions are shared more or less widely. In addition from these changes we could speculate evolutionary links between these centromeres.

  2. Inhibiting trophoblast PAR-1 overexpression suppresses sFlt-1-induced anti-angiogenesis and abnormal vascular remodeling: a possible therapeutic approach for preeclampsia.

    Science.gov (United States)

    Zhao, Yin; Zheng, YanFang; Liu, XiaoXia; Luo, QingQing; Wu, Di; Liu, XiaoPing; Zou, Li

    2018-03-01

    Is it possible to improve vascular remodeling by inhibiting the excessive expression of protease-activated receptor 1 (PAR-1) in trophoblast of abnormal placenta? Inhibition of trophoblast PAR-1 overexpression may promote placental angiogenesis and vascular remodeling, offering an alternative therapeutic approach for preeclampsia. PAR-1 is high-affinity receptor of thrombin. Thrombin increases sFlt-1 secretion in trophoblast via the activation of PAR-1. It is reported that the expression of both thrombin and PAR-1 expression are increased in placentas of preeclampsia patients compared with normal placentas. Trophoblast cells were transfected with PAR-1 short hairpin RNA (shRNA) or PAR-1 overexpression plasmids in vitro. Tube formation assays and a villus-decidua co-culture system were used to study the effect of PAR-1 inhibition on placental angiogenesis and vascular remodeling, respectively. Placentas from rats with preeclampsia were transfected with PAR-1 shRNA to confirm the effect of inhibiting PAR-1 overexpression in placenta. The trophoblast cell line HTR-8/SVneo was transfected with PAR-1 shRNA or PAR-1 overexpression plasmids. After 48 h, supernatant was collected and the level of sFlt-1 secretion was measured by ELISA. Human umbilical cord epithelial cells and a villus-decidua co-culture system were treated with conditioned media to study the effect of PAR-1 inhibition on tube formation and villi vascular remodeling. A preeclampsia rat model was established by intraperitoneal injection of L-NAME. Plasmids were injected into the placenta of the preeclampsia rats and systolic blood pressure was measured on Days 15 and 19. The effect of different treatments was evaluated by proteinuria, placental weights, fetal weights and fetal numbers in study and control groups. The level of serum sFlt-1 in rats with preeclampsia was also measured. Changes in the placenta microvessels were studied by histopathological staining. PAR-1 shRNA inhibited PAR-1 expression and

  3. Phosphorylation of Mycobacterium tuberculosis ParB participates in regulating the ParABS chromosome segregation system.

    Science.gov (United States)

    Baronian, Grégory; Ginda, Katarzyna; Berry, Laurence; Cohen-Gonsaud, Martin; Zakrzewska-Czerwińska, Jolanta; Jakimowicz, Dagmara; Molle, Virginie

    2015-01-01

    Here, we present for the first time that Mycobacterium tuberculosis ParB is phosphorylated by several mycobacterial Ser/Thr protein kinases in vitro. ParB and ParA are the key components of bacterial chromosome segregation apparatus. ParB is a cytosolic conserved protein that binds specifically to centromere-like DNA parS sequences and interacts with ParA, a weak ATPase required for its proper localization. Mass spectrometry identified the presence of ten phosphate groups, thus indicating that ParB is phosphorylated on eight threonines, Thr32, Thr41, Thr53, Thr110, Thr195, and Thr254, Thr300, Thr303 as well as on two serines, Ser5 and Ser239. The phosphorylation sites were further substituted either by alanine to prevent phosphorylation or aspartate to mimic constitutive phosphorylation. Electrophoretic mobility shift assays revealed a drastic inhibition of DNA-binding by ParB phosphomimetic mutant compared to wild type. In addition, bacterial two-hybrid experiments showed a loss of ParA-ParB interaction with the phosphomimetic mutant, indicating that phosphorylation is regulating the recruitment of the partitioning complex. Moreover, fluorescence microscopy experiments performed in the surrogate Mycobacterium smegmatis ΔparB strain revealed that in contrast to wild type Mtb ParB, which formed subpolar foci similar to M. smegmatis ParB, phoshomimetic Mtb ParB was delocalized. Thus, our findings highlight a novel regulatory role of the different isoforms of ParB representing a molecular switch in localization and functioning of partitioning protein in Mycobacterium tuberculosis.

  4. Phosphorylation of Mycobacterium tuberculosis ParB participates in regulating the ParABS chromosome segregation system.

    Directory of Open Access Journals (Sweden)

    Grégory Baronian

    Full Text Available Here, we present for the first time that Mycobacterium tuberculosis ParB is phosphorylated by several mycobacterial Ser/Thr protein kinases in vitro. ParB and ParA are the key components of bacterial chromosome segregation apparatus. ParB is a cytosolic conserved protein that binds specifically to centromere-like DNA parS sequences and interacts with ParA, a weak ATPase required for its proper localization. Mass spectrometry identified the presence of ten phosphate groups, thus indicating that ParB is phosphorylated on eight threonines, Thr32, Thr41, Thr53, Thr110, Thr195, and Thr254, Thr300, Thr303 as well as on two serines, Ser5 and Ser239. The phosphorylation sites were further substituted either by alanine to prevent phosphorylation or aspartate to mimic constitutive phosphorylation. Electrophoretic mobility shift assays revealed a drastic inhibition of DNA-binding by ParB phosphomimetic mutant compared to wild type. In addition, bacterial two-hybrid experiments showed a loss of ParA-ParB interaction with the phosphomimetic mutant, indicating that phosphorylation is regulating the recruitment of the partitioning complex. Moreover, fluorescence microscopy experiments performed in the surrogate Mycobacterium smegmatis ΔparB strain revealed that in contrast to wild type Mtb ParB, which formed subpolar foci similar to M. smegmatis ParB, phoshomimetic Mtb ParB was delocalized. Thus, our findings highlight a novel regulatory role of the different isoforms of ParB representing a molecular switch in localization and functioning of partitioning protein in Mycobacterium tuberculosis.

  5. Expressão imunoistoquímica da endoglina (CD105 e do fator de von Willebrand em carcinoma epidermoide oral e sua relação com parâmetros clinicopatológicos

    Directory of Open Access Journals (Sweden)

    Rodrigo Porpino Mafra

    2016-03-01

    Full Text Available Resumo Contexto A angiogênese tem sido associada à progressão de neoplasias malignas e, embora haja estudos acerca de marcadores angiogênicos no carcinoma epidermoide oral (CEO, existem resultados conflitantes na literatura. Objetivos Avaliar a expressão imunoistoquímica do CD105 e do fator de von Willebrand (FvW em CEO e sua relação com parâmetros clínicos do tumor. Métodos A imunoexpressão dos referidos biomarcadores foi analisada em 30 casos de CEO e correlacionada a parâmetros clínicos do tumor (idade e sexo dos pacientes, localização anatômica e estadiamento clínico Tumor, Nodo e Metástase, TNM. Resultados A imunomarcação com o anticorpo anti-FvW foi mais efetiva que a do CD105 no CEO. No que concerne à localização anatômica, o assoalho bucal e a região retromolar apresentaram diferenças estatisticamente significativas quanto aos índices angiogênicos (p = 0,004, determinados pela técnica de contagem microvascular (MVC. Não houve relação estatisticamente significativa entre o estadiamento clínico TNM e os índices angiogênicos, com os dois biomarcadores. Conclusões Com base nos achados deste estudo, sugere-se um envolvimento da neoformação vascular na carcinogênese oral, embora não tenha sido evidenciada associação significativa com o estágio clínico da lesão.

  6. 33 CFR 105.230 - Maritime Security (MARSEC) Level coordination and implementation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Maritime Security (MARSEC) Level..., DEPARTMENT OF HOMELAND SECURITY MARITIME SECURITY MARITIME SECURITY: FACILITIES Facility Security Requirements § 105.230 Maritime Security (MARSEC) Level coordination and implementation. (a) The facility owner...

  7. Analysis of ParB-centromere interactions by multiplex SPR imaging reveals specific patterns for binding ParB in six centromeres of Burkholderiales chromosomes and plasmids.

    Directory of Open Access Journals (Sweden)

    Flavien Pillet

    Full Text Available Bacterial centromeres-also called parS, are cis-acting DNA sequences which, together with the proteins ParA and ParB, are involved in the segregation of chromosomes and plasmids. The specific binding of ParB to parS nucleates the assembly of a large ParB/DNA complex from which ParA-the motor protein, segregates the sister replicons. Closely related families of partition systems, called Bsr, were identified on the chromosomes and large plasmids of the multi-chromosomal bacterium Burkholderia cenocepacia and other species from the order Burkholeriales. The centromeres of the Bsr partition families are 16 bp palindromes, displaying similar base compositions, notably a central CG dinucleotide. Despite centromeres bind the cognate ParB with a narrow specificity, weak ParB-parS non cognate interactions were nevertheless detected between few Bsr partition systems of replicons not belonging to the same genome. These observations suggested that Bsr partition systems could have a common ancestry but that evolution mostly erased the possibilities of cross-reactions between them, in particular to prevent replicon incompatibility. To detect novel similarities between Bsr partition systems, we have analyzed the binding of six Bsr parS sequences and a wide collection of modified derivatives, to their cognate ParB. The study was carried out by Surface Plasmon Resonance imaging (SPRi mulitplex analysis enabling a systematic survey of each nucleotide position within the centromere. We found that in each parS some positions could be changed while maintaining binding to ParB. Each centromere displays its own pattern of changes, but some positions are shared more or less widely. In addition from these changes we could speculate evolutionary links between these centromeres.

  8. Measurement of the effective $B_s^0\\rightarrow J/\\psi K_{\\mathrm S}^0$ lifetime

    CERN Document Server

    Aaij, R; Adeva, B; Adinolfi, M; Adrover, C; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves Jr, A A; Amato, S; Amerio, S; Amhis, Y; Anderlini, L; Anderson, J; Andreassen, R; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Bachmann, S; Back, J J; Baesso, C; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Bauer, Th; Bay, A; Beddow, J; Bedeschi, F; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bettler, M -O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Bowcock, T J V; Bowen, E; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Britsch, M; Britton, T; Brook, N H; Brown, H; Burducea, I; Bursche, A; Busetto, G; Buytaert, J; Cadeddu, S; Callot, O; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Campora Perez, D; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carranza-Mejia, H; Carson, L; Carvalho Akiba, K; Casse, G; Castillo Garcia, L; Cattaneo, M; Cauet, Ch; Charles, M; Charpentier, Ph; Chen, P; Chiapolini, N; Chrzaszcz, M; Ciba, K; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coca, C; Coco, V; Cogan, J; Cogneras, E; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombes, M; Coquereau, S; Corti, G; Couturier, B; Cowan, G A; Craik, D C; Cunliffe, S; Currie, R; D'Ambrosio, C; David, P; David, P N Y; Davis, A; De Bonis, I; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Silva, W; De Simone, P; Decamp, D; Deckenhoff, M; Del Buono, L; Déléage, N; Derkach, D; Deschamps, O; Dettori, F; Di Canto, A; Di Ruscio, F; Dijkstra, H; Dogaru, M; Donleavy, S; Dordei, F; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dupertuis, F; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; van Eijk, D; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; El Rifai, I; Elsasser, Ch; Elsby, D; Falabella, A; Färber, C; Fardell, G; Farinelli, C; Farry, S; Fave, V; Ferguson, D; Fernandez Albor, V; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fiore, M; Fitzpatrick, C; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Furcas, S; Furfaro, E; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garofoli, J; Garosi, P; Garra Tico, J; Garrido, L; Gaspar, C; Gauld, R; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gibson, V; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gordon, H; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Griffith, P; Grünberg, O; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hampson, T; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Hartmann, T; He, J; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Hicks, E; Hill, D; Hoballah, M; Hombach, C; Hopchev, P; Hulsbergen, W; Hunt, P; Huse, T; Hussain, N; Hutchcroft, D; Hynds, D; Iakovenko, V; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jans, E; Jaton, P; Jing, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Kaballo, M; Kandybei, S; Karacson, M; Karbach, T M; Kenyon, I R; Kerzel, U; Ketel, T; Keune, A; Khanji, B; Kochebina, O; Komarov, I; Koopman, R F; Koppenburg, P; Korolev, M; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kucharczyk, M; Kudryavtsev, V; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J -P; Lefèvre, R; Leflat, A; Lefrançois, J; Leo, S; Leroy, O; Lesiak, T; Leverington, B; Li, Y; Li Gioi, L; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; Lohn, S; Longstaff, I; Lopes, J H; Lopez Asamar, E; Lopez-March, N; Lu, H; Lucchesi, D; Luisier, J; Luo, H; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Malde, S; Manca, G; Mancinelli, G; Marconi, U; Märki, R; Marks, J; Martellotti, G; Martens, A; Martin, L; Martín Sánchez, A; Martinelli, M; Martinez Santos, D; Martins Tostes, D; Massafferri, A; Matev, R; Mathe, Z; Matteuzzi, C; Maurice, E; Mazurov, A; McCarthy, J; McNab, A; McNulty, R; Meadows, B; Meier, F; Meissner, M; Merk, M; Milanes, D A; Minard, M -N; Molina Rodriguez, J; Monteil, S; Moran, D; Morawski, P; Morello, M J; Mountain, R; Mous, I; Muheim, F; Müller, K; Muresan, R; Muryn, B; Muster, B; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Needham, M; Neufeld, N; Nguyen, A D; Nguyen, T D; Nguyen-Mau, C; Nicol, M; Niess, V; Niet, R; Nikitin, N; Nikodem, T; Nomerotski, A; Novoselov, A; Oblakowska-Mucha, A; Obraztsov, V; Oggero, S; Ogilvy, S; Okhrimenko, O; Oldeman, R; Orlandea, M; Otalora Goicochea, J M; Owen, P; Oyanguren, A; Pal, B K; Palano, A; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Parkes, C; Parkinson, C J; Passaleva, G; Patel, G D; Patel, M; Patrick, G N; Patrignani, C; Pavel-Nicorescu, C; Pazos Alvarez, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perego, D L; Perez Trigo, E; Pérez-Calero Yzquierdo, A; Perret, P; Perrin-Terrin, M; Pessina, G; Petridis, K; Petrolini, A; Phan, A; Picatoste Olloqui, E; Pietrzyk, B; Pilař, T; Pinci, D; Playfer, S; Plo Casasus, M; Polci, F; Polok, G; Poluektov, A; Polycarpo, E; Popov, A; Popov, D; Popovici, B; Potterat, C; Powell, A; Prisciandaro, J; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Rademacker, J H; Rakotomiaramanana, B; Rangel, M S; Raniuk, I; Rauschmayr, N; Raven, G; Redford, S; Reid, M M; dos Reis, A C; Ricciardi, S; Richards, A; Rinnert, K; Rives Molina, V; Roa Romero, D A; Robbe, P; Rodrigues, E; Rodriguez Perez, P; Roiser, S; Romanovsky, V; Romero Vidal, A; Rouvinet, J; Ruf, T; Ruffini, F; Ruiz, H; Ruiz Valls, P; Sabatino, G; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salustino Guimaraes, V; Salzmann, C; Sanmartin Sedes, B; Sannino, M; Santacesaria, R; Santamarina Rios, C; Santovetti, E; Sapunov, M; Sarti, A; Satriano, C; Satta, A; Savrie, M; Savrina, D; Schaack, P; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmidt, B; Schneider, O; Schopper, A; Schune, M -H; Schwemmer, R; Sciascia, B; Sciubba, A; Seco, M; Semennikov, A; Senderowska, K; Sepp, I; Serra, N; Serrano, J; Seyfert, P; Shapkin, M; Shapoval, I; Shatalov, P; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, O; Shevchenko, V; Shires, A; Silva Coutinho, R; Skwarnicki, T; Smith, N A; Smith, E; Smith, M; Sokoloff, M D; Soler, F J P; Soomro, F; Souza, D; Souza De Paula, B; Spaan, B; Sparkes, A; Spradlin, P; Stagni, F; Stahl, S; Steinkamp, O; Stoica, S; Stone, S; Storaci, B; Straticiuc, M; Straumann, U; Subbiah, V K; Sun, L; Swientek, S; Syropoulos, V; Szczekowski, M; Szczypka, P; Szumlak, T; T'Jampens, S; Teklishyn, M; Teodorescu, E; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Tolk, S; Tonelli, D; Topp-Joergensen, S; Torr, N; Tournefier, E; Tourneur, S; Tran, M T; Tresch, M; Tsaregorodtsev, A; Tsopelas, P; Tuning, N; Ubeda Garcia, M; Ukleja, A; Urner, D; Uwer, U; Vagnoni, V; Valenti, G; Vazquez Gomez, R; Vazquez Regueiro, P; Vecchi, S; Velthuis, J J; Veltri, M; Veneziano, G; Vesterinen, M; Viaud, B; Vieira, D; Vilasis-Cardona, X; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Vorobyev, V; Voß, C; Voss, H; Waldi, R; Wallace, R; Wandernoth, S; Wang, J; Ward, D R; Watson, N K; Webber, A D; Websdale, D; Whitehead, M; Wicht, J; Wiechczynski, J; Wiedner, D; Wiggers, L; Wilkinson, G; Williams, M P; Williams, M; Wilson, F F; Wishahi, J; Witek, M; Wotton, S A; Wright, S; Wu, S; Wyllie, K; Xie, Y; Xing, F; Xing, Z; Yang, Z; Young, R; Yuan, X; Yushchenko, O; Zangoli, M; Zavertyaev, M; Zhang, F; Zhang, L; Zhang, W C; Zhang, Y; Zhelezov, A; Zhokhov, A; Zhong, L; Zvyagin, A

    2013-01-01

    This paper reports the first measurement of the effective $B_s^0\\rightarrow J/\\psi K_{\\mathrm S}^0$ lifetime and an updated measurement of its time-integrated branching fraction. Both measurements are performed with a data sample, corresponding to an integrated luminosity of $1.0\\:\\text{fb}^{-1}$ of $pp$ collisions, recorded by the LHCb experiment in 2011 at a centre-of-mass energy of $7\\:\\text{TeV}$. The results are: $\\tau_{J/\\psi K_{\\mathrm S}^0}^{\\text{eff}} = 1.75 \\pm 0.12\\:(\\text{stat}) \\pm 0.07\\:(\\text{syst})\\:\\text{ps}$ and $\\mathcal{B}(B_s^0\\rightarrow J/\\psi K_{\\mathrm S}^0)=(1.97 \\pm 0.23)\\times 10^{-5}$. For the latter measurement, the uncertainty includes both statistical and systematic sources.

  9. 46 CFR 111.105-1 - Applicability; definition.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Applicability; definition. 111.105-1 Section 111.105-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Hazardous Locations § 111.105-1 Applicability; definition. This subpart applies to...

  10. 49 CFR 229.105 - Steam generator number.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Steam generator number. 229.105 Section 229.105..., DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Safety Requirements Steam Generators § 229.105 Steam generator number. An identification number shall be marked on the steam generator's...

  11. 44 CFR 18.105 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... services in the private sector. (o) Recipient includes all contractors, subcontractors at any tier, and... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Definitions. 18.105 Section... HOMELAND SECURITY GENERAL NEW RESTRICTIONS ON LOBBYING General § 18.105 Definitions. For purposes of this...

  12. The 105-Month Swift-BAT All-sky Hard X-Ray Survey

    Science.gov (United States)

    Oh, Kyuseok; Koss, Michael; Markwardt, Craig B.; Schawinski, Kevin; Baumgartner, Wayne H.; Barthelmy, Scott D.; Cenko, S. Bradley; Gehrels, Neil; Mushotzky, Richard; Petulante, Abigail; Ricci, Claudio; Lien, Amy; Trakhtenbrot, Benny

    2018-03-01

    We present a catalog of hard X-ray sources detected in the first 105 months of observations with the Burst Alert Telescope (BAT) coded-mask imager on board the Swift observatory. The 105-month Swift-BAT survey is a uniform hard X-ray all-sky survey with a sensitivity of 8.40× {10}-12 {erg} {{{s}}}-1 {cm}}-2 over 90% of the sky and 7.24× {10}-12 {erg} {{{s}}}-1 {cm}}-2 over 50% of the sky in the 14–195 keV band. The Swift-BAT 105-month catalog provides 1632 (422 new detections) hard X-ray sources in the 14–195 keV band above the 4.8σ significance level. Adding to the previously known hard X-ray sources, 34% (144/422) of the new detections are identified as Seyfert active galactic nuclei (AGNs) in nearby galaxies (zBAT catalog, we release eight-channel spectra and monthly sampled light curves for each object in the online journal and at the Swift-BAT 105-month website.

  13. Tank Vapor Characterization Project: Headspace vapor characterization of Hanford Tank 241-B-105: Results from samples collected on 07/30/96

    International Nuclear Information System (INIS)

    Pool, K.H.; Evans, J.C.; Thomas, B.L.

    1997-01-01

    This report describes the analytical results of vapor samples taken from the headspace of the waste storage tank 241-B-105 (Tank B-105) at the Hanford Site in Washington State. The results described in this report were obtained to characterize the vapors present in the tank headspace and to support safety evaluations and tank farm operations. The results include air concentrations of selected inorganic and organic analytes and grouped compounds from samples obtained by Westinghouse Hanford Company (WHC) and provided for analysis to Pacific Northwest National Laboratory (PNNL). Analyses were performed by the Vapor Analytical Laboratory (VAL) at PNNL. Analyte concentrations were based on analytical results and, where appropriate, sample volumes provided by WHC. A summary of the inorganic analytes, permanent gases, and total non-methane organic compounds is listed in Table S.1. The three highest concentration analytes detected in SUMMA trademark canister and triple sorbent trap samples are also listed in Table S.1. Detailed descriptions of the analytical results appear in the appendices

  14. Respect par les Canadiens de 10 à 17 ans des Directives canadiennes en matière de mouvement sur 24 heures pour les enfants et les jeunes

    Directory of Open Access Journals (Sweden)

    Ian Janssen

    2017-01-01

    Full Text Available Introduction : Le document Directives canadiennes en matière de mouvement sur 24 heures pour les enfants et les jeunes publié en 2016 contient des recommandations quant à l’activité physique quotidienne d’intensité moyenne à élevée, au temps de loisir passé devant un écran et au sommeil chez les jeunes de 5 à 17 ans. Cette étude a pour objectif d’estimer le pourcentage de Canadiens de 10 à 17 ans qui respectent ces recommandations. Méthodologie : Nous avons analysé un échantillon national représentatif de 22 115 jeunes. Les données sur le comportement actif ont été autodéclarées. Le respect des recommandations des Directives repose sur les éléments suivants : accumulation d’au moins 60 minutes par jour d’activité physique d’intensité moyenne à élevée, pas plus de 2 heures par jour de temps de loisir passé devant un écran et de 9 à 11 heures de sommeil continu par nuit pour les jeunes de 10 à 13 ans ou de 8 à 10 heures de sommeil continu par nuit pour les jeunes de 14 à 17 ans. Résultats : Seulement 3 % des jeunes de l’échantillon respectaient les trois recommandations clés. Vingt-cinq pour cent respectaient deux recommandations, 51 % en respectaient une et 21 % n’en respectaient aucune. La recommandation en matière de sommeil était la plus respectée par les enfants et les jeunes (66 %, suivie de celle en matière d’activité physique d’intensité moyenne à élevée (35 % et de celle relative au temps passé devant un écran (8 %. Conclusion : Une faible proportion (moins de 3 % de Canadiens de 10 à 17 ans respectent les trois principales recommandations des Directives canadiennes en matière de mouvement sur 24 heures pour les enfants et les jeunes.

  15. 46 CFR 111.105-41 - Battery rooms.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Battery rooms. 111.105-41 Section 111.105-41 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Hazardous Locations § 111.105-41 Battery rooms. Each electrical installation in a battery room...

  16. 46 CFR 14.105 - Disclosure and privacy.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Disclosure and privacy. 14.105 Section 14.105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE OFFICERS AND SEAMEN SHIPMENT AND DISCHARGE OF MERCHANT MARINERS General § 14.105 Disclosure and privacy. The Coast Guard makes information...

  17. 11 CFR 105.1 - Place of filing; House candidates and their authorized committees (2 U.S.C. 432(g)(1)).

    Science.gov (United States)

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Place of filing; House candidates and their authorized committees (2 U.S.C. 432(g)(1)). 105.1 Section 105.1 Federal Elections FEDERAL ELECTION COMMISSION GENERAL DOCUMENT FILING (2 U.S.C. 432(g)) § 105.1 Place of filing; House candidates and their authorized...

  18. 28 CFR 0.10 - Attorney General's Advisory Committee of U.S. Attorneys.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Attorney General's Advisory Committee of... DEPARTMENT OF JUSTICE Office of the Attorney General § 0.10 Attorney General's Advisory Committee of U.S. Attorneys. (a) The Attorney General's Advisory Committee of United States Attorneys shall consist of an...

  19. 12 CFR 268.105 - Individual complaints.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Individual complaints. 268.105 Section 268.105... RULES REGARDING EQUAL OPPORTUNITY Board Program To Promote Equal Opportunity § 268.105 Individual... individual and the Board and to describe generally the action(s) or practice(s) that form the basis of the...

  20. 46 CFR 105.45-5 - Galley fires.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Galley fires. 105.45-5 Section 105.45-5 Shipping COAST... VESSELS DISPENSING PETROLEUM PRODUCTS Special Operating Requirements § 105.45-5 Galley fires. (a) Galley fires are normally permitted during cargo transfer operations. However, prior to transferring Grade B or...

  1. Imaging of urokinase-type plasminogen activator receptor expression using a 64Cu-labeled linear peptide antagonist by microPET

    DEFF Research Database (Denmark)

    Li, Zi-Bo; Niu, Gang; Wang, Hui

    2008-01-01

    for positron emission tomography (PET) imaging. A linear, high-affinity uPAR-binding peptide antagonist AE105 was conjugated with 1,4,7,10-tetraazadodecane-N,N',N'',N'''-tetraacetic acid (DOTA) and labeled with (64)Cu for microPET imaging of mice bearing U87MG human glioblastoma (uPAR positive) and MDA-MB-435...... human breast cancer (uPAR negative). RESULTS: Surface plasmon resonance measurements show that AE105 with DOTA conjugated at the alpha-amino group (DOTA-AE105) has high affinity toward uPAR. microPET imaging reveals a rapid and high accumulation of (64)Cu-DOTA-AE105 in uPAR-positive U87MG tumors (10.......8 +/- 1.5%ID/g at 4.5 hours, n = 3) but not in uPAR-negative MDA-MB-435 tumors (1.2 +/- 0.6%ID/g at 4.5 hours, n = 3). Specificity of this peptide-based imaging of uPAR was validated by further control experiments. First, a nonbinding variant of AE105 carrying a single amino acid replacement (Trp...

  2. The 105-Month Swift-BAT All-Sky Hard X-Ray Survey

    Science.gov (United States)

    Oh, Kyuseok; Koss, Michael; Markwardt, Craig B.; Schawinski, Kevin; Baumgartner, Wayne H.; Barthelmy, Scott D.; Cenko, S. Bradley; Gehrels, Neil; Mushotzky, Richard; Petulante, Abigail; hide

    2018-01-01

    We present a catalog of hard X-ray sources detected in the first 105 months of observations with the Burst Alert Telescope (BAT) coded-mask imager on board the Swift observatory. The 105-month Swift-BAT survey is a uniform hard X-ray all-sky survey with a sensitivity of 8.40 x 10(exp -12) erg s(exp -1) cm(exp -2) over 90% of the sky and 7.24 x 10(exp -12) erg s(exp -1) cm(exp -2) over 50% of the sky in the 14-195 keV band. The Swift-BAT 105-month catalog provides 1632 (422 new detections) hard X-ray sources in the 14-195 keV band above the 4.8 sigma significance level. Adding to the previously known hard X-ray sources, 34% (144/422) of the new detections are identified as Seyfert active galactic nuclei (AGNs) in nearby galaxies (z < 0.2). The majority of the remaining identified sources are X-ray binaries (7%, 31) and blazars/BL Lac objects (10%, 43). As part of this new edition of the Swift-BAT catalog, we release eight-channel spectra and monthly sampled light curves for each object in the online journal and at the Swift-BAT 105-month website.

  3. Convenio Universidad de París VIII - Universidad Nacional de Colombia

    OpenAIRE

    Luis Alberto Cabulla Montaño

    1993-01-01

    El Departamento de Gestión Empresarial de la Facultad de Ciencias Económicas de la Universidad Nacional de Colombia ha celebrado un Acuerdo de Cooperación Interuniversitaria con la Universidad de París VID (Francia). Este Convenio responde al deseo común de facilitar y desarrollar relaciones de cooperación e intercambio en materia de investigación y enseñanza en áreas de interés común (Gestión, Economía y Sociologia), dentro del marco del Acuerdo Cultural Franco-Colombiano vigente entre los d...

  4. Supporting design information for portable exhauster installation at tanks S-109, SX-102/103, BY-105/106, S-101/102, and S-107

    International Nuclear Information System (INIS)

    Keller, C.M.

    1997-01-01

    This document provides supporting calculations and equipment dedication plans for portable exhausters and ductwork installed on tanks S-109, SX-102/103, BY-105/106, S-101/102, and S-107. The exhausters will ventilate the tanks during saltwell pumping to prevent the potential accumulation of flammable gases

  5. par genes in Mycobacterium bovis and Mycobacterium smegmatis are arranged in an operon transcribed from "SigGC" promoters

    Directory of Open Access Journals (Sweden)

    Casart Yveth

    2008-03-01

    Full Text Available Abstract Background The ParA/Soj and ParB/Spo0J proteins, and the cis-acting parS site, participate actively in chromosome segregation and cell cycle progression. Genes homologous to parA and parB, and two putative parS copies, have been identified in the Mycobacterium bovis BCG and Mycobacterium smegmatis chromosomes. As in Mycobacterium tuberculosis, the parA and parB genes in these two non-pathogenic mycobacteria are located near the chromosomal origin of replication. The present work focused on the determination of the transcriptional organisation of the ~6 Kb orf60K-parB region of M. bovis BCG and M. smegmatis by primer extension, transcriptional fusions to the green fluorescence protein (GFP and quantitative RT-PCR. Results The parAB genes were arranged in an operon. However, we also found promoters upstream of each one of these genes. Seven putative promoter sequences were identified in the orf60K-parB region of M. bovis BCG, whilst four were identified in the homologous region of M. smegmatis, one upstream of each open reading frame (ORF. Real-time PCR assays showed that in M. smegmatis, mRNA-parA and mRNA-parB levels decreased between the exponential and stationary phases. In M. bovis BCG, mRNA-parA levels also decreased between the exponential and stationary phases. However, parB expression was higher than parA expression and remained almost unchanged along the growth curve. Conclusion The majority of the proposed promoter regions had features characteristic of Mycobacterium promoters previously denoted as Group D. The -10 hexamer of a strong E. coli σ70-like promoter, located upstream of gidB of M. bovis BCG, overlapped with a putative parS sequence, suggesting that the transcription from this promoter might be regulated by the binding of ParB to parS.

  6. Effet de l'alimentation calcique séparée sur les performances de ...

    African Journals Online (AJOL)

    SARAH

    31 janv. 2016 ... RÉSUMÉ. Object : L'étude envisagée, se propose de vérifier la réponse de la souche Lhoman Brown soumise à l'alimentation calcique séparée. Elle s'inscrit dans le contexte de la sécurité alimentaire, la lutte contre la pauvreté et les changements climatiques sous climat tropical humide. Matériels et ...

  7. 41 CFR 105-68.335 - What information must I provide before entering into a covered transaction with the General...

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What information must I provide before entering into a covered transaction with the General Services Administration? 105-68.335 Section 105-68.335 Public Contracts and Property Management Federal Property Management Regulations System...

  8. 46 CFR 105.35-5 - Fire pumps.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Fire pumps. 105.35-5 Section 105.35-5 Shipping COAST... VESSELS DISPENSING PETROLEUM PRODUCTS Fire Extinguishing Equipment § 105.35-5 Fire pumps. (a) All vessels shall be provided with a hand operated portable fire pump having a capacity of at least 5 gallons per...

  9. 48 CFR 17.105-2 - Objectives.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Objectives. 17.105-2 Section 17.105-2 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACTING METHODS... contracts. (d) Substantial continuity of production or performance, thus avoiding annual startup costs...

  10. 46 CFR 111.105-35 - Vessels carrying coal.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Vessels carrying coal. 111.105-35 Section 111.105-35...-GENERAL REQUIREMENTS Hazardous Locations § 111.105-35 Vessels carrying coal. (a) The following are Class II, Division 1, (Zone 10 or Z) locations on a vessel that carries coal: (1) The interior of each coal...

  11. 48 CFR 873.105 - Acquisition planning.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Acquisition planning. 873.105 Section 873.105 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS DEPARTMENT... planning. (a) Acquisition planning is an indispensable component of the total acquisition process. (b) For...

  12. 42 CFR 56.105 - Accord with health planning.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Accord with health planning. 56.105 Section 56.105... HEALTH SERVICES General Provisions § 56.105 Accord with health planning. A grant may be made under this... appropriate health planning agencies have been met. ...

  13. 42 CFR 93.105 - Time limitations.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Time limitations. 93.105 Section 93.105 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH...

  14. Avaliação de parâmetros físicos e químicos e pesquisa de Vibrio parahaemolyticus em águas do estuário do rio Anil (São Luís, Estado do Maranhão - DOI: 10.4025/actascibiolsci.v25i2.1978 Evaluation of physical and chemical parameters and research on Vibrio parahaemolyticus in water samples from Anil river estuary (São Luis, state of Maranhão, Brazil- DOI: 10.4025/actascibiolsci.v25i2.1978

    Directory of Open Access Journals (Sweden)

    Adenilde Ribeiro Nascimento

    2003-04-01

    Full Text Available Avaliação dos parâmetros físico-químicos e isolamento de Vibrio parahaemolyticus em águas do estuário do rio Anil (São Luís-MA, Brasil, em bancos naturais de moluscos. Foi utilizada a técnica do Número Mais Provável (NMP com enriquecimento e subseqüente isolamento em agar tiossulfato-citrato-sacarose-sais-biliares (TCBS. Adicionalmente, foram monitorados “in situ” alguns parâmetros físico-químicos. As determinações para o pH variaram (7,25 a 7,90, O2 (0,20 a 1,2mg/L, T°C (29 a 32°C, S‰ (5 a 28,0 UPS, NH4+ (0,04 a 3,41mg/L, NO2- (0,10 a 1,91mg/L, PO43- (0,03 a 4,88mg/L. Em 56,1% na estação I e 55,4% na estação II, apresentaram positividade, para V. parahaemolyticus, com níveis entre 1,1x10 e > 1,1x105NMP/mL. Os resultados exigem uma atenção especial por parte dos órgãos de Controle Ambiental e de Saúde Pública locais, uma vez que os recursos vivos deste ecossistema são sistematicamente explorados pelas comunidades ribeirinhas para fins de consumo e comercializaçãoStudy of physical and chemical parameters and isolation of Vibrio parahaemolyticus in some water samples from Anil river estuary (São Luis, state of Maranhão, Brazil at natural banks of mollusks. The technique of the most probable number (MPN with enrichment and a subsequent isolation was used in Thiosulphate citrate bile salt agar (TCBS. In addition, some physical and chemical parameters were monitored “in situ”. The determinations for pH varied (7.25 to 7.90, O2 (0.20 to 1.2mg/L, T°C (29 to 32°C, S‰, (5 to 28.0 UPS, NH4+ (0.04 to 3.41mg/L, NO2- (0.10 to 1.91mg/L, PO43- (0.03 to 4.88mg/L. The presence of V. parahaemolyticus was detected in 56.1% of station I and 55.4% of station II with levels from 1.1x10 to 1.1x105MPN/mL. The results require some special attention from the environmental control and Public Health organizations as soon as possible because the riverain communities are exploring the alive resources from that ecosystem as

  15. 41 CFR 105-64.503 - What is an accounting of disclosures?

    Science.gov (United States)

    2010-07-01

    ... Administration 64-GSA PRIVACY ACT RULES 64.5-Disclosure of Records § 105-64.503 What is an accounting of... of the record, whichever is longer. The accounting of disclosure information includes the name of the... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What is an accounting of...

  16. Effect of Fe substitution on magnetocaloric effect in La0.7Sr0.3Mn1-xFexO3 (0.05≤x≤0.20)

    International Nuclear Information System (INIS)

    Barik, S.K.; Krishnamoorthi, C.; Mahendiran, R.

    2011-01-01

    We have studied the effect of Fe substitution on magnetic and magnetocaloric properties in La 0.7 Sr 0.3 Mn 1-x Fe x O 3 (x=0.05, 0.07, 0.10, 0.15, and 0.20) over a wide temperature range (T=10-400 K). It is shown that substitution by Fe gradually decreases the ferromagnetic Curie temperature (T C ) and saturation magnetization up to x=0.15 but a dramatic change occurs for x=0.2. The x=0.2 sample can be considered as a phase separated compound in which both short-range ordered ferromagnetic and antiferromagnetic phases coexist. The magnetic entropy change (-ΔS m ) was estimated from isothermal magnetization curves and it decreases with increase of Fe content from 4.4 J kg -1 K -1 at 343 K (x=0.05) to 1.3 J kg -1 K -1 at 105 K (x=0.2), under ΔH=5 T. The La 0.7 Sr 0.3 Mn 0.93 Fe 0.07 O 3 sample shows negligible hysteresis loss, operating temperature range over 60 K around room temperature with refrigerant capacity of 225 J kg -1 , and magnetic entropy of 4 J kg -1 K -1 which will be an interesting compound for application in room temperature refrigeration. - Research highlights: → We report magnetocaloric effect in La 0.7 Sr 0.3 Mn 1-x Fe x O 3 (x=0-0.2). → Magnetic entropy change (ΔS m ) decreases with increasing x. → A large ΔS m and refrigeration capacity are found around 300 K in x=0.07.

  17. 48 CFR 570.105-1 - Contracting by negotiation.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Contracting by negotiation. 570.105-1 Section 570.105-1 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CONTRACTING PROGRAMS ACQUIRING LEASEHOLD INTERESTS IN REAL PROPERTY General 570.105-1 Contracting by negotiation. Contracting by negotiation...

  18. Effet de l'alimentation calcique séparée sur les performances de ...

    African Journals Online (AJOL)

    Object : L'étude envisagée, se propose de vérifier la réponse de la souche Lhoman Brown soumise à l'alimentation calcique séparée. Elle s'inscrit dans le contexte de la sécurité alimentaire, la lutte contre la pauvreté et les changements climatiques sous climat tropical humide. Matériels et méthodes : L'étude a été menée ...

  19. 12 CFR 411.105 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Definitions. 411.105 Section 411.105 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES NEW RESTRICTIONS ON LOBBYING General § 411.105 Definitions. For purposes of this part: (a) Agency, as defined in 5 U.S.C. 552(f), includes Federal executive...

  20. 41 CFR 105-68.330 - What requirements must I pass down to persons at lower tiers with whom I intend to do business?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What requirements must I pass down to persons at lower tiers with whom I intend to do business? 105-68.330 Section 105-68.330... Business with Other Persons § 105-68.330 What requirements must I pass down to persons at lower tiers with...

  1. Improved positron emission tomography imaging of glioblastoma cancer using novel 68Ga-labeled peptides targeting the urokinase-type plasminogen activator receptor (uPAR)

    DEFF Research Database (Denmark)

    Loft, Mathias Dyrberg; Sun, Yao; Liu, Changhao

    2017-01-01

    for non-invasive positron emission tomography (PET) imaging of uPAR. Despite the optimal physical properties of68Ga for peptide-based PET imaging, low tumor uptakes have previously been reported using68Ga-labeled AE105-NH2-based tracers. In an attempt to optimize the tumor uptake, we developed three novel...... to the non-spacer version, NODAGA-AE105-NH2. Following radiolabeling with68Ga, we evaluated the in vitro and in vivo performance in mice bearing subcutaneous tumors derived from the uPAR-expressing human GBM cell line U87MG. In vivo PET/CT imaging showed that introduction of PEG spacers more than doubled...... confirmed the improved tumor uptakes of the PEG-modified tracers.68Ga-NODAGA-PEG8-AE105-NH2is thus a promising candidate for human translation for PET imaging of GBM....

  2. Renforcement des capacités de recherche grâce au mentorat par ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Ce projet de recherche-action consistera en un programme collaboratif de mentorat par les pairs conçu pour renforcer les capacités de recherche sur les technologies de l'information et de la communication au service du développement dans les pays du Sud. Le programme sera axé sur les compétences requises pour ...

  3. El acuerdo de París: entre lo posible y lo necesario

    OpenAIRE

    Heras Hernández, Francisco

    2017-01-01

    El 12 de Diciembre de 2015 en el seno de Naciones Unidas 195 países adoptaron el denominado Acuerdo de París, comprometiéndose a limitar las emisiones de gases de efecto invernadero(GEI), que son el motor del cambio climático. Una vez pasadas las primeras reacciones de satisfaccióno de decepción, el desarrollo del Acuerdo suscita una serie de interrogantes: ¿Qué retos plantea a las partes firmantes? ¿Qué repercusiones tendrá en el corto y en el medio plazo? Y lo más importante: ¿Será un i...

  4. 41 CFR 105-68.325 - What happens if I do business with an excluded person in a covered transaction?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What happens if I do business with an excluded person in a covered transaction? 105-68.325 Section 105-68.325 Public Contracts...-68.325 What happens if I do business with an excluded person in a covered transaction? If as a...

  5. 47 CFR 101.105 - Interference protection criteria.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Interference protection criteria. 101.105 Section 101.105 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO.... (ii) To accommodate co-primary Direct Broadcast Satellite Service earth stations, an MVDDS...

  6. Elevated soluble urokinase plasminogen activator receptor (suPAR) predicts mortality in Staphylococcus aureus bacteremia

    DEFF Research Database (Denmark)

    Mölkänen, T; Ruotsalainen, E; Thorball, C W

    2011-01-01

    The soluble form of urokinase-type plasminogen activator receptor (suPAR) is a new inflammatory marker. High suPAR levels have been shown to associate with mortality in cancer and in chronic infections like HIV and tuberculosis, but reports on the role of suPAR in acute bacteremic infections...... are scarce. To elucidate the role of suPAR in a common bacteremic infection, the serum suPAR levels in 59 patients with Staphylococcus aureus bacteremia (SAB) were measured using the suPARnostic ELISA assay and associations to 1-month mortality and with deep infection focus were analyzed. On day three, after...... the first positive blood culture for S. aureus, suPAR levels were higher in 19 fatalities (median 12.3; range 5.7-64.6 ng/mL) than in 40 survivors (median 8.4; range 3.7-17.6 ng/mL, p = 0.002). This difference persisted for 10 days. The presence of deep infection focus was not associated with elevated su...

  7. La pelade par plaques

    Science.gov (United States)

    Spano, Frank; Donovan, Jeff C.

    2015-01-01

    Résumé Objectif Présenter aux médecins de famille des renseignements de base pour faire comprendre l’épidémiologie, la pathogenèse, l’histologie et l’approche clinique au diagnostic de la pelade par plaques. Sources des données Une recension a été effectuée dans PubMed pour trouver des articles pertinents concernant la pathogenèse, le diagnostic et le pronostic de la pelade par plaques. Message principal La pelade par plaques est une forme de perte pileuse auto-immune dont la prévalence durant une vie est d’environ 2 %. Des antécédents personnels ou familiaux de troubles auto-immuns concomitants, comme le vitiligo ou une maladie de la thyroïde, peuvent être observés dans un petit sous-groupe de patients. Le diagnostic peut souvent être posé de manière clinique en se fondant sur la perte de cheveux non cicatricielle et circulaire caractéristique, accompagnée de cheveux en « point d’exclamation » en périphérie chez ceux dont le problème en est aux premiers stades. Le diagnostic des cas plus complexes ou des présentations inhabituelles peut être facilité par une biopsie et un examen histologique. Le pronostic varie largement et de mauvais résultats sont associés à une apparition à un âge précoce, une perte importante, la variante ophiasis, des changements aux ongles, des antécédents familiaux ou des troubles auto-immuns concomitants. Conclusion La pelade par plaques est une forme auto-immune de perte de cheveux périodiquement observée en soins primaires. Les médecins de famille sont bien placés pour identifier la pelade par plaques, déterminer la gravité de la maladie et poser le diagnostic différentiel approprié. De plus, ils sont en mesure de renseigner leurs patients à propos de l’évolution clinique de la maladie ainsi que du pronostic général selon le sous-type de patients.

  8. Nécrose pancréatique infectieuse des salmonidés : évaluation de méthodes destinées à couper la transmission par l'oeuf

    Directory of Open Access Journals (Sweden)

    DORSON M.

    1996-01-01

    Full Text Available Des ovules de truites Arc-en-Ciel ont été fécondés par des spermatozoïdes de la même espèce traités par l'iode suivant différents protocoles afin de couper la transmission de la nécrose pancréatique infectieuse (NPI des salmonidés. L'efficacité de l'iode a été évaluée en parallèle par neutralisation du virus en 1 mn. Le protocole conseillé pour la solution d'iode disponible dans le commerce (ovules égouttés, puis recouverts de solution- iodée et sperme ajouté immédiatement a d'abord été utilisé. A pH compris entre 5 et 8 et pour des concentrations en iode de 15, 25 et 35 mg/l, le pourcentage de fécondation est inférieur à 10 et ne remonte qu'à pH 9 (69 % pour 25 mg/l. Par contre, l'efficacité contre le virus décroît rapidement pour des pH supérieurs à 7, et aucun pH n'a permis de concilier efficacité et innocuité. Le même protocole'utilisé avec 10 spermes individuels a montré des différences de sensibilité individuelle marquées (pourcentages de fécondation de 1,6 à 37 % pour 25 mg/l d'iode à pH8, qui ne sont pas en corrélation avec la qualité des spermes appréciée par la concentration de la protéine de membrane 42 kDa dans le liquide séminal. Les différents essais de préincubation du sperme (de quelques secondes à 1 minute ont donné des rendements de fécondation nuls, sauf pour un large excès de sperme, qui entraînait aussi la perte de l'efficacité de l'iode contre le virus. Deux expériences de transmission expérimentale ont été réalisées en incubant les spermatozoïdes avec du virus concentré. L'élimination systématique des oeufs morts et anormaux suivie d'une désinfection externe des oeufs (50 mg/l d'iode, 15 mn avant l'éclosion n'a pas permis dé couper la transmission, ce qui laisse supposer que le virus peut être transmis sans infecter l'embryon de façon létale.

  9. 41 CFR 105-68.450 - What action may I take if a primary tier participant fails to disclose the information required...

    Science.gov (United States)

    2010-07-01

    ... Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General Services... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What action may I take if a primary tier participant fails to disclose the information required under § 105-68.335? 105-68...

  10. 41 CFR 105-74.220 - By when must I publish my drug-free workplace statement and establish my drug-free awareness...

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false By when must I publish my drug-free workplace statement and establish my drug-free awareness program? 105-74.220 Section 105-74.220 Public Contracts and Property Management Federal Property Management Regulations System...

  11. 48 CFR 1.105-1 - Publication and code arrangement.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Publication and code arrangement. 1.105-1 Section 1.105-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL FEDERAL ACQUISITION REGULATIONS SYSTEM Purpose, Authority, Issuance 1.105-1 Publication and code...

  12. 48 CFR 401.105-1 - Publication and code arrangement.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Publication and code arrangement. 401.105-1 Section 401.105-1 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL AGRICULTURE ACQUISITION REGULATION SYSTEM Purpose, Authority, Issuance 401.105-1 Publication and...

  13. PAR-1 contributes to the innate immune response during viral infection

    Science.gov (United States)

    Antoniak, Silvio; Owens, A. Phillip; Baunacke, Martin; Williams, Julie C.; Lee, Rebecca D.; Weithäuser, Alice; Sheridan, Patricia A.; Malz, Ronny; Luyendyk, James P.; Esserman, Denise A.; Trejo, JoAnn; Kirchhofer, Daniel; Blaxall, Burns C.; Pawlinski, Rafal; Beck, Melinda A.; Rauch, Ursula; Mackman, Nigel

    2013-01-01

    Coagulation is a host defense system that limits the spread of pathogens. Coagulation proteases, such as thrombin, also activate cells by cleaving PARs. In this study, we analyzed the role of PAR-1 in coxsackievirus B3–induced (CVB3-induced) myocarditis and influenza A infection. CVB3-infected Par1–/– mice expressed reduced levels of IFN-β and CXCL10 during the early phase of infection compared with Par1+/+ mice that resulted in higher viral loads and cardiac injury at day 8 after infection. Inhibition of either tissue factor or thrombin in WT mice also significantly increased CVB3 levels in the heart and cardiac injury compared with controls. BM transplantation experiments demonstrated that PAR-1 in nonhematopoietic cells protected mice from CVB3 infection. Transgenic mice overexpressing PAR-1 in cardiomyocytes had reduced CVB3-induced myocarditis. We found that cooperative signaling between PAR-1 and TLR3 in mouse cardiac fibroblasts enhanced activation of p38 and induction of IFN-β and CXCL10 expression. Par1–/– mice also had decreased CXCL10 expression and increased viral levels in the lung after influenza A infection compared with Par1+/+ mice. Our results indicate that the tissue factor/thrombin/PAR-1 pathway enhances IFN-β expression and contributes to the innate immune response during single-stranded RNA viral infection. PMID:23391721

  14. Proinflammatory cytokines tumor necrosis factor-alpha and interferon-gamma alter tight junction structure and function in the rat parotid gland Par-C10 cell line.

    Science.gov (United States)

    Baker, Olga J; Camden, Jean M; Redman, Robert S; Jones, Jonathan E; Seye, Cheikh I; Erb, Laurie; Weisman, Gary A

    2008-11-01

    Sjögren's syndrome (SS) is an autoimmune disorder characterized by inflammation and dysfunction of salivary glands, resulting in impaired secretory function. The production of the proinflammatory cytokines tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) is elevated in exocrine glands of patients with SS, although little is known about the effects of these cytokines on salivary epithelial cell functions necessary for saliva secretion, including tight junction (TJ) integrity and the establishment of transepithelial ion gradients. The present study demonstrates that chronic exposure of polarized rat parotid gland (Par-C10) epithelial cell monolayers to TNF-alpha and IFN-gamma decreases transepithelial resistance (TER) and anion secretion, as measured by changes in short-circuit current (I(sc)) induced by carbachol, a muscarinic cholinergic receptor agonist, or UTP, a P2Y(2) nucleotide receptor agonist. In contrast, TNF-alpha and IFN-gamma had no effect on agonist-induced increases in the intracellular calcium concentration [Ca(2+)](i) in Par-C10 cells. Furthermore, treatment of Par-C10 cell monolayers with TNF-alpha and IFN-gamma increased paracellular permeability to normally impermeant proteins, altered cell and TJ morphology, and downregulated the expression of the TJ protein, claudin-1, but not other TJ proteins expressed in Par-C10 cells. The decreases in TER, agonist-induced transepithelial anion secretion, and claudin-1 expression caused by TNF-alpha, but not IFN-gamma, were reversible by incubation of Par-C10 cell monolayers with cytokine-free medium for 24 h, indicating that IFN-gamma causes irreversible inhibition of cellular activities associated with fluid secretion in salivary glands. Our results suggest that cytokine production is an important contributor to secretory dysfunction in SS by disrupting TJ integrity of salivary epithelium.

  15. 48 CFR 501.105-1 - Publication and code arrangement.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Publication and code arrangement. 501.105-1 Section 501.105-1 Federal Acquisition Regulations System GENERAL SERVICES... 501.105-1 Publication and code arrangement. The GSAR is published in the following sources: (a) Daily...

  16. 48 CFR 3001.105-1 - Publication and code arrangement.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Publication and code arrangement. 3001.105-1 Section 3001.105-1 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND... Purpose, Authority, Issuance 3001.105-1 Publication and code arrangement. (a) The HSAR is published in: (1...

  17. 41 CFR 105-68.445 - What action may I take if a primary tier participant knowingly does business with an excluded or...

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What action may I take if a primary tier participant knowingly does business with an excluded or disqualified person? 105-68.445 Section 105-68.445 Public Contracts and Property Management Federal Property Management...

  18. La tradició de Jesús i el procés de reinterpretació. La paràbola dels vinyaters com a exemple

    OpenAIRE

    Puig i Tàrrech, Armand

    2013-01-01

    En la paràbola dels vinyaters hi ha quatre elements que possibiliten les relectures que es van succeint a l’interior de la tradició de Jesús. Tots quatre pertanyen a l’esquema narratiu primitiu de la paràbola: a) la vinya plantada, b) l’enviament dels servents, c) el fill (estimat) i d) la pedra. Les tradicions que fan autoritat, i de les quals s’afirma la inspiració divina, són dues: l’Escriptura i les paraules mateixes de Jesús. Cada element de la paràbola és rellegit d’acord am...

  19. Japānas un Amerikas Savienoto Valstu kauja par Okinavu 1945. gada: 1.aprīlis – 22. jūnijs

    OpenAIRE

    Leimanis, Normunds

    2017-01-01

    Bakalaura darba tēmas nosaukums ir „Japānas un Amerikas Savienoto Valstu kauja par Okinavu 1945. gada: 1. aprīlis – 22. jūnijs ”. Tā ir viena no lielākajām un asiņainākajām kaujām, kura notika Otrā Pasaules kara laika beigās. Tā bija viena no pēdējām kaujām Otrā Pasaules kara laikā. Kaujā par Okinavu piedalijās amerikāņu un japāņu karaspēki, kas cīnījās par savu valsti un tās godu. Galvenie Okinavas kaujas dalībnieki bija japāņu 32. armija un amerikāņu 10.armija. Galvenais atbildīgais par ...

  20. 41 CFR 105-71.112 - Special grant or subgrant conditions for “high-risk” grantees.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Special grant or... Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION... COOPERATIVE AGREEMENTS WITH STATE AND LOCAL GOVERNMENTS 71.11-Pre-Award Requirements § 105-71.112 Special...

  1. 42 CFR 402.105 - Amount of penalty.

    Science.gov (United States)

    2010-10-01

    ... insurance benefit plans (§ 402.1(c)(21)). (b) $1,000. CMS or OIG may impose a penalty of not more than $1... 42 Public Health 2 2010-10-01 2010-10-01 false Amount of penalty. 402.105 Section 402.105 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL...

  2. 46 CFR 105.35-15 - Fire hose.

    Science.gov (United States)

    2010-10-01

    ... bronze or equivalent metal. (e) All fittings on fire hose shall be of brass, copper, or other suitable corrosion resistant metal. (f) A length of fire hose shall be attached to each fire hydrant at all times... 46 Shipping 4 2010-10-01 2010-10-01 false Fire hose. 105.35-15 Section 105.35-15 Shipping COAST...

  3. Parâmetros astrofísicos de estrelas gigantes do aglomerado globular 47 Tucanae

    Science.gov (United States)

    Alves-Brito, A.; Barbuy, B.

    2003-08-01

    Os aglomerados globulares são considerados laboratórios astrofísicos para a verificação da teoria de evolução estelar, bem como a trajetória químio-dinâmica das galáxias hospedeiras. Em particular, 47 Tucanae (NGC 104) configura-se como um dos mais extensivamente estudados aglomerados globulares da Galáxia devido a relativa proximidade ao Sol (R¤ = 4.5 kpc) e alta latitute galáctica (b = -44°,89). Neste trabalho, apresentamos a velocidade radial heliocêntrica e os parâmetros atmosféricos (Teff, logg, [Fe/H]) de 5 estrelas gigantes do aglomerado globular 47 Tucanae. Os espectros foram obtidos pelo espectrógrafo UVES (Ultaviolet Visual Echelle Spectrograph) de alta resolução (R = 60000) e alta razão sinal-ruído (S/N > 200), acoplado ao telescópio de 8,2m Kueyen do VLT (Very Large Telescope). Nós encontramos = -22,43 +/- 3,97 km/s, [Fe/H] ~ -0.7, 1,2 estrelas cobrem um intervalo de magnitude 12,2 < V < 14,2. Os parâmetros atmosféricos são fundamentais para a construção de espectros sintéticos de outros aglomerados globulares ricos em metais. Trabalho financiado pela FAPESP e pelo CNPq.

  4. The assembly histories of quiescent galaxies since z = 0.7 from absorption line spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Jieun; Conroy, Charlie [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States); Moustakas, John [Department of Physics and Astronomy, Siena College, Loudonville, NY 12110 (United States); Graves, Genevieve J. [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States); Holden, Bradford P. [UCO/Lick Observatories, University of California, Santa Cruz, CA 95064 (United States); Brodwin, Mark [Department of Physics and Astronomy, University of Missouri, Kansas City, MO 64110 (United States); Brown, Michael J. I. [School of Physics, Monash University, Clayton, Vic 3800 (Australia); Van Dokkum, Pieter G. [Department of Astrophysical Sciences, Yale University, New Haven, CT 06520 (United States)

    2014-09-10

    We present results from modeling the optical spectra of a large sample of quiescent galaxies between 0.1 < z < 0.7 from the Sloan Digital Sky Survey (SDSS) and the AGN and Galaxy Evolution Survey (AGES). We examine how the stellar ages and abundance patterns of galaxies evolve over time as a function of stellar mass from 10{sup 9.6}-10{sup 11.8} M {sub ☉}. Galaxy spectra are stacked in bins of mass and redshift and modeled over a wavelength range from 4000 Å to 5500 Å. Full spectrum stellar population synthesis modeling provides estimates of the age and the abundances of the elements Fe, Mg, C, N, and Ca. We find negligible evolution in elemental abundances at fixed stellar mass over roughly 7 Gyr of cosmic time. In addition, the increase in stellar ages with time for massive galaxies is consistent with passive evolution since z = 0.7. Taken together, these results favor a scenario in which the inner ∼0.3-3 R {sub e} of massive quiescent galaxies have been passively evolving over the last half of cosmic time. Interestingly, the derived stellar ages are considerably younger than the age of the universe at all epochs, consistent with an equivalent single-burst star formation epoch of z ≲ 1.5. These young stellar population ages coupled with the existence of massive quiescent galaxies at z > 1 indicate the inhomogeneous nature of the z ≲ 0.7 quiescent population. The data also permit the addition of newly quenched galaxies at masses below ∼10{sup 10.5} M {sub ☉} at z < 0.7. Additionally, we analyze very deep Keck DEIMOS spectra of the two brightest quiescent galaxies in a cluster at z = 0.83. There is tentative evidence that these galaxies are older than their counterparts in low-density environments. In the Appendix, we demonstrate that our full spectrum modeling technique allows for accurate and reliable modeling of galaxy spectra to low S/N (∼20 Å{sup –1}) and/or low spectral resolution (R ∼ 500).

  5. 42 CFR 431.105 - Consultation to medical facilities.

    Science.gov (United States)

    2010-10-01

    ... State agencies furnish consultative services to hospitals, nursing homes, home health agencies, clinics... 42 Public Health 4 2010-10-01 2010-10-01 false Consultation to medical facilities. 431.105 Section 431.105 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN...

  6. Profils des enfants infectes par le vih en debut du traitement ...

    African Journals Online (AJOL)

    But : Décrire les profils des enfants infectés par le VIH au début du traitement antirétroviral. Matériels et méthode: Les dossiers des enfants infectés par le VIH dans la région maritime ont été analysés de mai 2008 à février 2010 par le comité thérapeutique. Résultats: Parmi les 96 dossiers analysés, 66,67% venaient du ...

  7. Narrative Identities and the Plebiscite in Pará: An Analysis of the Front Pages for O Liberal and Diário do Pará

    Directory of Open Access Journals (Sweden)

    Alda Cristina Silva da Costa

    2017-05-01

    Full Text Available On December 11, 2011, a plebiscite was held in Pará proposing to create two separatist states, Carajás and Tapajós, out of the state of Pará. The public voted against both projects. This article analyzes the narrative identities found on the front pages of O Liberal and Diário do Pará newspapers about the plebiscite in Pará. Depth Hermeneutics (DH, as proposed by Thompson (2011, was used as the methodological reference. DH emphasizes the object of analysis as a meaningful symbolic construction requiring interpretation. Narrative analysis, as proposed by Motta (2007, was the main research technique used to highlight the movement of construction of journalistic (discursive characters. The narrative identities built by the two newspapers showed that both were against the creation of the new states, but for very different reasons. The flag of Pará was the main object used to induce the idea of unity. Em 11 de dezembro de 2011, o plebiscito no Pará propôs a criação dos estados de Carajás e de Tapajós a partir da divisão do estado do Pará. O resultado da consulta pública foi negativo aos dois projetos. O artigo analisa as identidades narrativas constituídas pelas primeiras páginas dos jornais O Liberal e Diário do Pará sobre o plebiscito no Pará. Utilizou-se como referencial metodológico a Hermenêutica em Profundidade (HP, proposta por Thompson (2011. A HP evidencia o fato de que o objeto de análise é uma construção simbólica significativa, que exige uma interpretação. Como principal técnica de pesquisa, a análise narrativa, proposta por Motta (2007, com ênfase no movimento de construção de personagens jornalísticas (discursivas. As identidades narrativas construídas pelos dois jornais indicaram que ambos eram contrários à criação dos novos estados, porém por motivos divergentes. A bandeira do Pará foi o principal elemento utilizado para evocar a ideia de unidade. En 11 de diciembre de 2011, el plebiscito en

  8. ParABS Systems of the Four Replicons of Burkholderia cenocepacia: New Chromosome Centromeres Confer Partition Specificity†

    Science.gov (United States)

    Dubarry, Nelly; Pasta, Franck; Lane, David

    2006-01-01

    Most bacterial chromosomes carry an analogue of the parABS systems that govern plasmid partition, but their role in chromosome partition is ambiguous. parABS systems might be particularly important for orderly segregation of multipartite genomes, where their role may thus be easier to evaluate. We have characterized parABS systems in Burkholderia cenocepacia, whose genome comprises three chromosomes and one low-copy-number plasmid. A single parAB locus and a set of ParB-binding (parS) centromere sites are located near the origin of each replicon. ParA and ParB of the longest chromosome are phylogenetically similar to analogues in other multichromosome and monochromosome bacteria but are distinct from those of smaller chromosomes. The latter form subgroups that correspond to the taxa of their hosts, indicating evolution from plasmids. The parS sites on the smaller chromosomes and the plasmid are similar to the “universal” parS of the main chromosome but with a sequence specific to their replicon. In an Escherichia coli plasmid stabilization test, each parAB exhibits partition activity only with the parS of its own replicon. Hence, parABS function is based on the independent partition of individual chromosomes rather than on a single communal system or network of interacting systems. Stabilization by the smaller chromosome and plasmid systems was enhanced by mutation of parS sites and a promoter internal to their parAB operons, suggesting autoregulatory mechanisms. The small chromosome ParBs were found to silence transcription, a property relevant to autoregulation. PMID:16452432

  9. Investigation of $K_{L,S} \\rightarrow \\pi^{+}\\pi^{-}e^{+}e^{-}$ decays

    CERN Document Server

    Lai, A; Arcidiacono, R; Barr, G; Becker, H G; Bevan, A; Biino, C; Bizzeti, A; Bocquet, G; Calvetti, M; Cartiglia, N; Casali, R; Ceccucci, Augusto; Cenci, P; Cerri, C; Cheshkov, C; Chollet, J C; Chèze, J B; Cirilli, M; Clemencic, M; Cogan, J; Collazuol, G; Contalbrigo, M; Costantini, F; Cundy, Donald C; Dalpiaz, Pietro; De Beer, M; Debu, P; Doble, Niels T; Dosanjh, R S; Duclos, J; Eppard, M; Falaleev, V P; Fantechi, R; Fayard, Louis; Fischer, G; Formica, A; Fox, H; Frabetti, P L; Gaponenko, A N; Gatignon, L; Gershon, T J; Gianoli, A; Giudici, Sergio; Gonidec, A; Gorini, B; Govi, G; Grafström, P; Granier de Cassagnac, R; Graziani, G; Hay, B; Holder, M; Holtz, K; Iacopini, E; Iconomidou-Fayard, L; Imbergamo, E; Jeitler, Manfred; Kalmus, George Ernest; Kalter, A; Kekelidze, V D; Khristov, P Z; Kleinknecht, K; Knowles, I; Koch, U; Kubischta, Werner; Köpke, L; Lazzeroni, C; Lenti, M; Lopes da Silva, P; Lubrano, P; Luitz, S; Madigozhin, D T; Maier, A; Mannelli, I; Marchetto, F; Markytan, Manfred; Marouelli, P; Marras, D; Martin, V; Martini, M; Masetti, L; Mazzucato, E; Menichetti, E; Mestvirishvili, A; Mikulec, I; Munday, D J; Nappi, A; Nassalski, J P; Needham, M D; Neuhofer, Günther; Norton, A; Ocariz, J; Olaiya, E; Palestini, S; Panzer-Steindel, B; Parker, M A; Pellmann, I A; Pepé, M; Pernicka, Manfred; Peters, A; Petrucci, F; Peyaud, B; Piccini, M; Pierazzini, G M; Potrebenikov, Yu K; Rondio, Ewa; Sacco, R; Savrié, M; Schmidt, S; Schué, Yu; Schönharting, V; Sozzi, M; Szleper, M; Tatishvili, G T; Taureg, Hans; Taurok, Anton; Turlay, René; Unal, G; Vallage, B; Velasco, M; Veltri, M; Wahl, H; Walker, A; Wanke, R; White, T O; Widhalm, L; Wingerter-Seez, I; Winhart, A; Wislicki, W; Wittgen, M; Wotton, S A; Wronka, S; Zinchenko, A I; Ziolkowski, M

    2003-01-01

    The K_L -> pi+pi-e+e- and K_S -> pi+pi-e+e- decay modes have been studied in detail using the NA48 detector at CERN SPS. Based on the data collected during the 1998 and 1999 run periods, a sample of 1162 K_L -> pi+pi-e+e- candidates has been observed with an expected background level of 36.9 events, yielding the branching ratio measurement BR(K_L -> pi+pi-e+e-)=(3.08+-0.20)x10^-7. The distribution of events in the sin\\phicos\\phi variable, where \\phi is the angle between the pi+pi- and the e+e- decay planes in the kaon centre of mass, is found to exhibit a large CP-violating asymmetry with the value A_\\phi(14.2+-3.6)%. For the K_S -> pi+pi-e+e- decay channel, 621 candidates have been identified in the 1999 data sample with an estimated background contribution of 0.7 event. The corresponding branching ratio has been determined to be BR(K_S -> pi+pi-e+e-)=(4.71+-0.32)x10^-5. The combined value of this measurement with the published 1998 result id BR(K_S -> pi+pi-e+e-)=4.69+-0.30)x10^-5. No asymmetry is observed ...

  10. A Biocontrol Strain of Bacillus subtilis WXCDD105 Used to Control Tomato Botrytis cinerea and Cladosporium fulvum Cooke and Promote the Growth of Seedlings

    Directory of Open Access Journals (Sweden)

    Hui Wang

    2018-05-01

    Full Text Available In this study, a strain named WXCDD105, which has strong antagonistic effects on Botrytis cinerea and Cladosporium fulvum Cooke, was screened out from the rhizosphere of healthy tomato plants. The tomato plants had inhibition diameter zones of 5.00 mm during the dual culture for four days. Based on the morphological and physiological characteristics, the 16S rDNA sequence, and the gyrB gene sequence analysis, the strain WXCDD105 was identified as Bacillus subtilis suBap. subtilis. The results of the mycelial growth test showed that the sterile filtrate of the strain WXCDD105 could significantly inhibit mycelial growth of Botrytis cinerea and Cladosporium fulvum Cooke. The inhibition rates were 95.28 and 94.44%, respectively. The potting experiment showed that the strain WXCDD105 made effective the control of tomato gray mold and tomato leaf mold. The control efficiencies were 74.70 and 72.07%. The antagonistic test results showed that the strain WXCDD105 had different degrees of inhibition on 10 kinds of plant pathogenic fungi and the average inhibition rates were more than 80%. We also found that the strain WXCDD105 stimulated both the seed germination and seedling growth of tomatoes. Using the fermentation liquid of WXCDD105 (108 cfu·mL−1 to treat the seeds, the germination rate and radicle length were increased. Under the treatment of the fermentation liquid of the strain WXCDD105 (106 cfu·mL−1, nearly all physiological indexes of tomato seedlings were significantly higher than that of the control groups. This could not only keep the nutritional quality of tomato fruits but also prevent them from rotting. This study provided us with an excellent strain for biological control of tomato gray mold, tomato leaf mold, and tomato growth promotion. This also laid the technical foundation for its application.

  11. 18 CFR 1315.105 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... services in the private sector. (o) Recipient includes all contractors, subcontractors at any tier, and... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Definitions. 1315.105... LOBBYING General § 1315.105 Definitions. For purposes of this part: (a) Agency, as defined in 5 U.S.C. 552...

  12. 46 CFR 111.105-45 - Vessels carrying agricultural products.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Vessels carrying agricultural products. 111.105-45... ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Hazardous Locations § 111.105-45 Vessels carrying agricultural products. (a) The following areas are Class II, Division 1, (Zone 10 or Z) locations on vessels...

  13. Échecs thérapeutiques chez les enfants infectés par le VIH en suivi ...

    African Journals Online (AJOL)

    Introduction: L'objectif de cette étude était de déterminer les facteurs associés aux échecs thérapeutiques chez les enfants infectés par le VIH à l'Hôpital Laquintinie de Douala. Méthodes: Une étude transversale rétrospective a été menée sur une période de 5 mois en 2010, recrutant 222 enfants âgés de 1 à 18 ans et sous ...

  14. SAHARA MAKEUP NOV 07

    African Journals Online (AJOL)

    Winnie

    Mots clés: Education par les pairs et le soutien, prévention du VIH, éducation sur le VIH à l'école, ..... HIV and drug awareness days including drama, song, dance and ...... Sexual and Relationships Therapy, 15(3), 283-296. .... Family Planning.

  15. Microhabitats utilisés par les alevins 0+ d'une communauté de cyprins rhéophiles : analyse de l'évolution de la communauté et des densités de population

    Directory of Open Access Journals (Sweden)

    BARAS E.

    1995-04-01

    Full Text Available L'évolution de l'occupation des microhabitats par les alevins de la communauté de cyprins rhéophiles de l'Ourthe a été étudiée au cours de l'été et de l'automne 1994 par échantillonnage ponctuel d'abondance (électrodes fixes prépositionnées, courant continu. 16155 poissons (10-75 mm appartenant à 15 espèces ont été recensés sur 78 sites d'échantillonnage de 2 m2 . Les espèces les plus représentées étaient Leuciscus cephalus, Leuciscus leuciscus et Chondrostoma nasus (respectivement 43,6 %, 20,7 % et 16,7 % des captures estivales. L'analyse factorielle des correspondances d'une matrice site x (espèce x taille met en évidence une subdivision progressive de la communauté au cours de l'été en espèces d'eau vive (B. barbus et L. leuciscus et d'eau lente, davantage associées à un couvert végétal (L. cephalus et C. nasus. La densité maximale observée (fin juin est de 1500 alevins (25 mm m-2, correspondant à une biomasse de 250 g m-2. Le modèle explicatif de la densité généré par analyse de régression multiple pas-à-pas explique 60,0 % de la variabilité de la densité par les variables vitesse de courant, température de l'eau et date d'échantillonnage, cette variable intégrant le concept de mortalité-dispersion au cours de la saison de croissance. Les implications de la méthodologie et des résultats présentés au plan de la gestion des écosystèmes lotiques sont brièvement discutés.

  16. Choriocarcinome gestationnel révélé par une métastase rénale

    African Journals Online (AJOL)

    B. Sadiki

    d'une néphrectomie d'hémostase en cas d'hématurie persistante. La néphrectomie peut être remplacée par une embolisation sélective. [10]. Conclusion. Les métastases rénales du CG sont rares. Cette éventualité doit être évoquée par l'urologue en présence d'un syndrome tumoral rénal chez les patientes en âge de ...

  17. Parálisis facial periférica después de amigdalectomía extracapsular

    Directory of Open Access Journals (Sweden)

    Erwin Alejandro Racines-Alava

    2018-05-01

    Full Text Available Introducción y objetivo: La amigdalectomía extracapsular es uno de los procedimientos más frecuentes en Otorrinolaringología. No suelen ocurrir complicaciones salvo las derivadas de problemas de sangrado. Presentamos dos casos de parálisis facial en el postoperatorio inmediato y sus posibles causas. Material y Método: Realizamos la adenoamigdalectomía siempre bajo anestesia general. Colocamos a los pacientes en posición de Rose, y usamos un abrebocas de Mc Ivor. La adenoidectomía se realizó mediante curetaje. Posteriormente se infiltró bupivacaina + epinefrina 2.5/0.005 mg/ml en cada pilar anterior. La amigdalectomía total se realizó con pinza bipolar con mínimo sangrado. Caso 1: Niña de 4 años con un peso de 11Kg con antecedente de retardo de crecimiento, diagnosticada de SAHOS moderado, se le realizo adenoamigdalectomía total. La paciente abandonó el quirófano en buenas condiciones. En la sala de recuperación se observa una parálisis facial periférica grado IV de la clasificación House-Brackmann. La parálisis facial se resolvió en las siguientes 12 horas, se administró una pauta descendente de prednisona 1mgkg/día. Caso 2: Niña de 2 años con un peso de 17 kg sin antecedentes de importancia, diagnosticada de SAHOS moderado, se le realizó una adenoamigdalectomía total. En el posoperatorio inmediato, al extubar a la paciente se observa una parálisis facial izquierda grado III de la clasificación de House-Brackmann. Finalmente, la parálisis mejoró progresivamente en 6 horas, se administró una dosis de prednisona 1mg/kg. Resultados: La dosis máxima de Bupivacaína en los niños es de 2mg/kg. La presencia de vasoconstrictor disminuye la velocidad de absorción, con lo que disminuye la toxicidad sistémica, prolonga la duración de acción, aumenta la intensidad del bloqueo y disminuye la hemorragia quirúrgica. En la literatura nos encontramos escasos casos descritos de parálisis facial siguiendo amigdalectom

  18. Directed and persistent movement arises from mechanochemistry of the ParA/ParB system.

    Science.gov (United States)

    Hu, Longhua; Vecchiarelli, Anthony G; Mizuuchi, Kiyoshi; Neuman, Keir C; Liu, Jian

    2015-12-22

    The segregation of DNA before cell division is essential for faithful genetic inheritance. In many bacteria, segregation of low-copy number plasmids involves an active partition system composed of a nonspecific DNA-binding ATPase, ParA, and its stimulator protein ParB. The ParA/ParB system drives directed and persistent movement of DNA cargo both in vivo and in vitro. Filament-based models akin to actin/microtubule-driven motility were proposed for plasmid segregation mediated by ParA. Recent experiments challenge this view and suggest that ParA/ParB system motility is driven by a diffusion ratchet mechanism in which ParB-coated plasmid both creates and follows a ParA gradient on the nucleoid surface. However, the detailed mechanism of ParA/ParB-mediated directed and persistent movement remains unknown. Here, we develop a theoretical model describing ParA/ParB-mediated motility. We show that the ParA/ParB system can work as a Brownian ratchet, which effectively couples the ATPase-dependent cycling of ParA-nucleoid affinity to the motion of the ParB-bound cargo. Paradoxically, this resulting processive motion relies on quenching diffusive plasmid motion through a large number of transient ParA/ParB-mediated tethers to the nucleoid surface. Our work thus sheds light on an emergent phenomenon in which nonmotor proteins work collectively via mechanochemical coupling to propel cargos-an ingenious solution shaped by evolution to cope with the lack of processive motor proteins in bacteria.

  19. Effect of Fe substitution on magnetocaloric effect in La{sub 0.7}Sr{sub 0.3}Mn{sub 1-x}Fe{sub x}O{sub 3} (0.05{<=}x{<=}0.20)

    Energy Technology Data Exchange (ETDEWEB)

    Barik, S K; Krishnamoorthi, C [Department of Physics and NUS Nanoscience and Nanotechnology Initiative, 2 Science Drive 3, National University of Singapore, Singapore 117542, Singapore. (Singapore); Mahendiran, R [Department of Physics and NUS Nanoscience and Nanotechnology Initiative, 2 Science Drive 3, National University of Singapore, Singapore 117542, Singapore. (Singapore)

    2011-04-15

    We have studied the effect of Fe substitution on magnetic and magnetocaloric properties in La{sub 0.7}Sr{sub 0.3}Mn{sub 1-x}Fe{sub x}O{sub 3} (x=0.05, 0.07, 0.10, 0.15, and 0.20) over a wide temperature range (T=10-400 K). It is shown that substitution by Fe gradually decreases the ferromagnetic Curie temperature (T{sub C}) and saturation magnetization up to x=0.15 but a dramatic change occurs for x=0.2. The x=0.2 sample can be considered as a phase separated compound in which both short-range ordered ferromagnetic and antiferromagnetic phases coexist. The magnetic entropy change (-{Delta}S{sub m}) was estimated from isothermal magnetization curves and it decreases with increase of Fe content from 4.4 J kg{sup -1} K{sup -1} at 343 K (x=0.05) to 1.3 J kg{sup -1} K{sup -1} at 105 K (x=0.2), under {Delta}H=5 T. The La{sub 0.7}Sr{sub 0.3}Mn{sub 0.93}Fe{sub 0.07}O{sub 3} sample shows negligible hysteresis loss, operating temperature range over 60 K around room temperature with refrigerant capacity of 225 J kg{sup -1}, and magnetic entropy of 4 J kg{sup -1} K{sup -1} which will be an interesting compound for application in room temperature refrigeration. - Research highlights: > We report magnetocaloric effect in La{sub 0.7}Sr{sub 0.3}Mn{sub 1-x}Fe{sub x}O{sub 3} (x=0-0.2). > Magnetic entropy change ({Delta}S{sub m}) decreases with increasing x. > A large {Delta}S{sub m} and refrigeration capacity are found around 300 K in x=0.07.

  20. Removal Action Workplan for the 105-DR and 105-F Building Interim Safe Storage Projects and Ancillary Buildings

    International Nuclear Information System (INIS)

    Rodovsky, T. J.

    1999-01-01

    This document is the removal action workplan (RAW) for the 105-DR and 105-F Reactor Buildings and ancillary facilities. These buildings and facilities are located in the 100-D/DR and 100-F Areas of the Hanford Site in Benton County, Washington, which is owned and operated by the U.S. Department of Energy (DOE). The 100 Areas (including 100-D/DR and 100-F Areas) of the Hanford Site were placed on the U.S. Environmental Protection Agency's (EPA) National Priorities List under the Comprehensive Environmental Response, Compensation,and Liability Act of 1980 (CERCLA). DOE has determined that hazardous substances in the 105-DR and 105-F Reactor Buildings and four ancillary facilities present a potential threat to human health or the environment DOE has also determined that a non-time critical removal action is warranted at these facilities

  1. 46 CFR 105.05-2 - Prohibitions regarding petroleum products.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Prohibitions regarding petroleum products. 105.05-2... VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Application § 105.05-2 Prohibitions regarding petroleum products. (a) Commercial fishing vessels shall not transport Grade A flammable liquids...

  2. Comparaison du Pangola (Digitaria decumbens) et du Stargrass (Cynodon nlemfluensis) exploités par des ovins

    OpenAIRE

    Boval, Maryline

    1989-01-01

    A la Martinique l'utilisation comparée de Digitaria decumbens (Dd) et de Cynodon nlemfuensis (Cn) par des brebis allaitantes a été étudiée pendant une période d'observation de 6 mois. Le cheptel est à un taux élevé de 1 600 kg de poids vif par hectare et par an, obtenu par une fertilisation de 450 kg/ha/an en azote.

  3. 41 CFR 105-74.500 - How are violations of this part determined for recipients other than individuals?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false How are violations of... Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL... DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Violations of this Part and Consequences § 105-74.500 How...

  4. PARs for combustible gas control in advanced light water reactors

    International Nuclear Information System (INIS)

    Hosler, J.; Sliter, G.

    1997-01-01

    This paper discusses the progress being made in the United States to introduce passive autocatalytic recombiner (PAR) technology as a cost-effective alternative to electric recombiners for controlling combustible gas produced in postulated accidents in both future Advanced Light Water Reactors (ALWRs) and certain U. S. operating nuclear plants. PARs catalytically recombine hydrogen and oxygen, gradually producing heat and water vapor. They have no moving parts and are self-starting and self-feeding, even under relatively cold and wet containment conditions. Buoyancy of the hot gases they create sets up natural convective flow that promotes mixing of combustible gases in a containment. In a non-inerted ALWR containment, two approaches each employing a combination of PARs and igniters are being considered to control hydrogen in design basis and severe accidents. In pre-inerted ALWRs, PARs alone control radiolytic oxygen produced in either accident type. The paper also discusses regulatory feedback regarding these combustible gas control approaches and describes a test program being conducted by the Electric Power Research Institute (EPRI) and Electricite de France (EdF) to supplement the existing PAR test database with performance data under conditions of interest to U.S. plants. Preliminary findings from the EPRI/EdF PAR model test program are included. Successful completion of this test program and confirmatory tests being sponsored by the U. S. NRC are expected to pave the way for use of PARs in ALWRs and operating plants. (author)

  5. Stratégies agricoles développées par les ménages ruraux affectés ...

    African Journals Online (AJOL)

    Dans la plupart des pays africains touchés par le VIH/SIDA, l'agriculture est la principale activité et demeure essentiellement dépendante de la force humaine. Dès lors, les effets de cette pandémie sur l'agriculture ne sont plus à démontrer. Mais face au VIH/SIDA, les ménages affectés mettent en oeuvre diverses stratégies ...

  6. 42 CFR 51c.105 - Accord with health planning.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Accord with health planning. 51c.105 Section 51c... COMMUNITY HEALTH SERVICES General Provisions § 51c.105 Accord with health planning. A grant may be made... approval by the appropriate health planning agencies have been met. ...

  7. 41 CFR 105-68.310 - What must I do if a Federal agency excludes a person with whom I am already doing business in a...

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What must I do if a Federal agency excludes a person with whom I am already doing business in a covered transaction? 105-68... Regarding Transactions Doing Business with Other Persons § 105-68.310 What must I do if a Federal agency...

  8. taenia coli de cobaye

    African Journals Online (AJOL)

    AKA BOKO

    . Ces effets inotropes positifs antagonisés par l'Atropine (10-6mg/mL) sont totalement abolis en milieu pauvre (0Ca2+) et dépourvus de calcium (0Ca2++ EDTA 10-5M).Ces résultats suggèrent la présence de substances cholinomimétiques ...

  9. Prise en charge des intoxications par envenimation chez les enfants ...

    African Journals Online (AJOL)

    Les signes cliniques étaient dominés par les douleurs (98%) suivies des hémorragies (73,80%) pour les morsures de serpent, la douleur pour les piqures de scorpion (100%) et les oedèmes pour les piqures d'abeilles (100%). Les cas de morsure de serpent ont été traités par le sérum antivenimeux polyvalent. Conclusion: ...

  10. 46 CFR 111.105-33 - Mobile offshore drilling units.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Mobile offshore drilling units. 111.105-33 Section 111... ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Hazardous Locations § 111.105-33 Mobile offshore drilling units. (a) Applicability. This section applies to each mobile offshore drilling unit. (b) Definitions. As used in this...

  11. Un débat d'experts organisé par le CRDI s'attaque au mariage ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    8 mars 2018 ... Des chercheurs appuyés par le CRDI parleront de leurs expériences de lutte contre le mariage d'enfants, précoce et forcé lors du forum parallèle sur les ONG qui aura lieu pendant la 62e session annuelle de la Commission de la condition de la femme à New York. Plus de 700 millions de filles se ...

  12. 105-KE basin pilot run relocation

    International Nuclear Information System (INIS)

    Crystal, J.B.

    1994-01-01

    The purpose of this document is to present the bases for selecting the exact in-facility location for installation of process equipment to support pilot testing activities in the 105-KE Basin at the United States Department of Energy Hanford Site, in southeastern Washington State. The 105-KE Basin was constructed during the early 1950s, as an integralcomponent of the 105-K East reactor building. Similar basins were provided in all Hanford weapons production reactor buildings to receive fuel elements discharged from the reactors and stage them for rail transport to 200 Area fuel reprocessing plants. The 105-KE reactor began operation in 1955. It was shut down in 1971. However, the 105-KE Basin was reactivated several years later to store spent fuel from the N-Reactor basin and permit its continued operation during outages at the Plutonium Uranium Extraction (PUREX) plant in the 200E Area

  13. FooPar

    DEFF Research Database (Denmark)

    Hargreaves, F. P.; Merkle, D.

    2013-01-01

    We present FooPar, an extension for highly efficient Parallel Computing in the multi-paradigm programming language Scala. Scala offers concise and clean syntax and integrates functional programming features. Our framework FooPar combines these features with parallel computing techniques. Foo......, results based on a empirical analysis on two supercomputers are given. We achieve close-to-optimal performance wrt. theoretical peak performance. Based on this result we conclude that FooPar allows programmers to fully access Scalas design features without suffering from performance drops when compared...

  14. The prognostic value of sST2 and galectin-3 considering different aetiologies in non-ischaemic heart failure.

    Science.gov (United States)

    Binas, David; Daniel, Hanna; Richter, Anette; Ruppert, Volker; Schlüter, Klaus-Dieter; Schieffer, Bernhard; Pankuweit, Sabine

    2018-01-01

    Several studies indicate a prognostic value of sST2 and galectin-3 in heart failure (HF). While previous studies focused on ischaemic cause of HF, we investigated the role of sST2 and galectin-3 in patients with non-ischaemic dilated cardiomyopathy (DCM). sST2 and galectin-3 serum concentrations were measured in 262 subjects with DCM. Survival rates were determined for all-cause mortality (ACM) and cardiac mortality (CM). In a univariate model, sST2 as a continuous variable was a predictor of ACM (HR 1.05; 95% CI 1.03 to 1.07, PACM (HR 1.10; 95% CI 1.05 to 1.17, PACM (HR 1.04; 95% CI 1.01 to 1.07, P=0.019) was significant. In a multivariate model, the prognostic value of the sST2 main group remained intact for ACM (HR 1.04; 95% CI 1.02 to 1.07, P=0.003).Univariate and multivariate analysis of galectin-3 as continuous variable did not show any significant result. However, in a quartile model, intermediate values of galectin-3 were significantly associated with a lower event rate of ACM and CM. The study revealed that sST2 predicts ACM and CM in patients with non-ischaemic HF and could be useful especially in patients with inflammatory background. Our findings that intermediate levels of galectin-3 allow for better prognosis were new and different to other investigations. NCT03090425; Results.

  15. 46 CFR 190.07-1 - Application.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Application. 190.07-1 Section 190.07-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS CONSTRUCTION AND ARRANGEMENT Structural Fire Protection § 190.07-1 Application. (a) The provisions of this subpart, with the...

  16. 46 CFR 195.07-1 - Application.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Application. 195.07-1 Section 195.07-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS VESSEL CONTROL AND MISCELLANEOUS SYSTEMS AND EQUIPMENT Anchors, Chains, and Hawsers § 195.07-1 Application. (a) The provisions of...

  17. Apoplejía pituitaria con parálisis del III par craneal: Reporte de caso

    Directory of Open Access Journals (Sweden)

    Miguel Pinto Valdivia

    2011-10-01

    Full Text Available Se describe el caso de un varón de 65 años de edad, sin antecedentes patológicos de importancia, que acudió a emergencia del Hospital Nacional Cayetano Heredia por presentar cefalea intensa y ptosis palpebral izquierda. El examen físico mostró parálisis aislada del III par craneal izquierdo. Los análisis de laboratorio mostraron hiponatremia e hipopituitarismo y la resonancia magnética nuclear un adenoma pituitario con áreas de hemorragia e invasión de los senos cavernosos. El tratamiento incluyó glucocorticoides y descompresión quirúrgica transesfenoidal. La anatomía patológica confirmó el diagnóstico de infarto hemorrágico de un adenoma pituitario. El paciente fue dado de alta con terapia sustitutiva de levotiroxina y prednisona. La ptosis palpebral izquierda se recuperó en forma parcial. La apoplejía pituitaria es un síndrome clínico producido por un proceso expansivo dentro de la silla turca, secundario a hemorragia o infarto de un adenoma pituitario, que se caracteriza por cefalea, déficit visual, oftalmoplejía y alteración del nivel de conciencia. Este proceso expansivo puede comprimir los pares craneales en los senos cavernosos, produciendo diferentes grados de parálisis de los músculos oculomotores. La parálisis aislada del III par craneal es rara.(Rev Med Hered 2011;22:186-189.

  18. L'avenir du Moyen-Orient et de l'Afrique du Nord passe par la ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    10 janv. 2013 ... Centre de recherches pour le développement international Gouvernement du Canada ... du Nord passe par la croissance partagée et l'économie de marché ... vivant en région éloignée aient un accès égal aux possibilités économiques. ... visant à trouver de nouveaux modes d'action pouvant contribuer au ...

  19. Nuclear-physical properties of 105,106m,110mAg

    International Nuclear Information System (INIS)

    Popov, Yu. S.; Zakharova, L. V.; Sadulin, V. V.; Andreev, O. I.; Pakhomov, A. N.

    2005-01-01

    The nuclear-physical properties of the nuclides 105,106m,110m Ag, which are concomitant nuclides in reactor production of 103 Pd and 109 Cd used in metrology of ionizing radiations and in nuclear medicine, were studied. The following quantities were determined by semiconductor X-ray and γ-ray spectrometry: the parameter K α /K β of X-ray K radiation accompanying the decay of 110m Ag and the intensities of γ-ray quanta with the energies of 280 and 345 keV ( 105 Ag); 430, 451, and 512 keV ( 106m Ag); 658, 764, 885, 938, and 1384 keV ( 110m Ag). The half-lives determined using the above γ-ray lines are as follows: T 1/2 ( 105 Ag) = 41.2 ± 0.1 days; T 1/2 ( 106m Ag) = 8.30 ± 0.07 days. The errors are given for 95% confidence level [ru

  20. Positron emission tomography imaging of CD105 expression during tumor angiogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Hao [University of Wisconsin - Madison, Department of Radiology, Madison, WI (United States); Yang, Yunan [University of Wisconsin - Madison, Department of Radiology, Madison, WI (United States); Third Military Medical University, Department of Ultrasound, Xinqiao Hospital, Chongqing (China); Zhang, Yin; Engle, Jonathan W.; Barnhart, Todd E.; Nickles, Robert J. [University of Wisconsin - Madison, Department of Medical Physics, Madison, WI (United States); Leigh, Bryan R. [TRACON Pharmaceuticals, Inc., San Diego, CA (United States); Cai, Weibo [University of Wisconsin - Madison, Department of Radiology, Madison, WI (United States); University of Wisconsin - Madison, Department of Medical Physics, Madison, WI (United States); University of Wisconsin Carbone Cancer Center, Madison, WI (United States); University of Wisconsin - Madison, Departments of Radiology and Medical Physics, School of Medicine and Public Health, Madison, WI (United States)

    2011-07-15

    Overexpression of CD105 (endoglin) correlates with poor prognosis in many solid tumor types. Tumor microvessel density (MVD) assessed by CD105 staining is the current gold standard for evaluating tumor angiogenesis in the clinic. The goal of this study was to develop a positron emission tomography (PET) tracer for imaging CD105 expression. TRC105, a chimeric anti-CD105 monoclonal antibody, was conjugated to 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) and labeled with {sup 64}Cu. FACS analysis and microscopy studies were performed to compare the CD105 binding affinity of TRC105 and DOTA-TRC105. PET imaging, biodistribution, blocking, and ex vivo histology studies were performed on 4T1 murine breast tumor-bearing mice to evaluate the ability of {sup 64}Cu-DOTA-TRC105 to target tumor angiogenesis. Another chimeric antibody, cetuximab, was used as an isotype-matched control. FACS analysis of human umbilical vein endothelial cells (HUVECs) revealed no difference in CD105 binding affinity between TRC105 and DOTA-TRC105, which was further validated by fluorescence microscopy. {sup 64}Cu labeling was achieved with high yield and specific activity. Serial PET imaging revealed that the 4T1 tumor uptake of the tracer was 8.0 {+-} 0.5, 10.4 {+-} 2.8, and 9.7 {+-} 1.8%ID/g at 4, 24, and 48 h post-injection, respectively (n = 3), higher than most organs at late time points which provided excellent tumor contrast. Biodistribution data as measured by gamma counting were consistent with the PET findings. Blocking experiments, control studies with {sup 64}Cu-DOTA-cetuximab, as well as ex vivo histology all confirmed the in vivo target specificity of {sup 64}Cu-DOTA-TRC105. This is the first successful PET imaging study of CD105 expression. Fast, prominent, persistent, and CD105-specific uptake of the tracer in the 4T1 tumor was observed. Further studies are warranted and currently underway. (orig.)

  1. Evaluation des activités antioxydante et antibactérienne de l’huile essentielle de Citrus limon (variété Lisbon extraite par hydrodistillation

    Directory of Open Access Journals (Sweden)

    Louiza HIMED

    2016-03-01

    Full Text Available La présente étude porte sur l’évaluation des propriétés antioxydante et antibactérienne de l’huile essentielle de Citrus limon (Lisbon extraite par hydrodistillation et analysée par GC-MS. Le pouvoir antioxydant est évalué par le test au DPPH et le test de blanchissement du β-carotène. L’activité antibactérienne vis-à-vis de neuf souches bactériennes (deux à Gram positif et sept à Gram négatif est évaluée par la méthode des aromatogrammes et la méthode de dilution d’agar pour déterminer les CMI. L’extraction a donné un rendement moyen de 1,34±0,012%. Cette huile essentielle a montré des propriétés antioxydante et antibactérienne importantes. La concentration efficace qui réduit 50 % du DPPH en solution est de 0,09±0,001 µg/ml qui exprime une activité antioxydante plus importante que celle de α-tocopherol, ce résultat a été confirmé par le test de blanchissement du β-carotène. Les bactéries testées ont montré une sensibilité à l’huile essentielle. Ces activités sont liées à la richesse de l’huile essentielle en monoterpènes (81,01%.

  2. 46 CFR 42.07-60 - Control.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Control. 42.07-60 Section 42.07-60 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES DOMESTIC AND FOREIGN VOYAGES BY SEA Control, Enforcement, and Rights of Appeal § 42.07-60 Control. (a) The District Director of Customs or the Coast Guard...

  3. [Ambroise Paré, his death and his historians].

    Science.gov (United States)

    Dumaître, P

    2001-01-01

    Ambroise Paré died December the 20th., 1590. What happened after his death and what are we knowing about his life? Never forgotten, though a lack of care, we were waiting till the XIXth. century to get recollection upon a subject sustained only by accounts of his travels. After Percy, a surgeon who tried to write Paré's biography through the "Biographie universelle ancienne et moderne, de Michaud (1822)" and some second rank authors, Malgaigne is the first who inside a printing of the "Oeuvres complétes de Paré (1840-41)" has a fine look upon the question, though his work is incomplete and allows many mistakes. Doctors Chéreau and Jal, an historian, analysing civil status records, gave new information enlarged by doctors Le Paulmier, Turner and the U.S. native Janet Doe.

  4. 40 CFR 174.502 - Bacillus thuringiensis Cry1A.105 protein; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Bacillus thuringiensis Cry1A.105 protein; exemption from the requirement of a tolerance. 174.502 Section 174.502 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS PROCEDURES AND REQUIREMENTS FOR PLANT-INCORPORATED PROTECTANTS Tolerances and...

  5. Relações do parâmetro S para algumas propriedades físicas de solos do sul do Brasil Relationships of the S parameter of some physical properties of soils of southern Brazil

    Directory of Open Access Journals (Sweden)

    Carlos Arnoldo Streck

    2008-12-01

    Full Text Available O parâmetro S representa o valor da inclinação da curva de retenção de água no seu ponto de inflexão. Um aumento nos valores de S indica uma ampla distribuição de tamanho de poros, condizente com condições estruturais que estabelecem um adequado funcionamento físico do solo. Neste trabalho, testou-se a sensibilidade do parâmetro S, proposto na literatura, em relação a algumas propriedades físicas de solos do Sul do Brasil. O parâmetro S não se relacionou com o teor de argila total, nem com o teor de argila dispersa dos sete solos utilizados neste trabalho. Para o grupamento dos solos argilosos e muito argilosos, o parâmetro S apresentou decréscimo exponencial com o aumento da densidade do solo e um crescimento exponencial com o aumento da matéria orgânica do solo. Nesses solos, a água disponível às plantas aumentou de forma linear (ADP= 3,19*S passando pela origem e a pressão de pré-consolidação reduziu exponencialmente com o aumento do valor de S. Conclui-se que o parâmetro S apresentou sensibilidade para determinar a qualidade física dos solos de textura argilosa e muito argilosa.The S index corresponds to the slope of the soil water retention curve at its inflection point. A high S value indicates the presence of structural pores, which are essential for a good soil physical condition. The objective of this study was to evaluate the sensitivity of the index of soil physical quality (S, as proposed in the literature for some physical properties of soils from Southern Brazil. In the seven soils used here, no relationship was found between clay and water dispersible clay content with soil physical quality index S. However, in soils with high clay content, the S index decreases with an increase in soil bulk density and increases with an increase in soil organic matter content. For a given texture class, plant available water increased linearly (PAW= 3.19*S to the origin and the preconsolidation pressure decreased

  6. 5 CFR 2610.105 - Eligibility of applicants.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Eligibility of applicants. 2610.105 Section 2610.105 Administrative Personnel OFFICE OF GOVERNMENT ETHICS ORGANIZATION AND PROCEDURES... cooperative association as defined in section 15(a) of the Agricultural Marketing Act, 12 U.S.C. 1141j(a...

  7. 37 CFR 1.105 - Requirements for information.

    Science.gov (United States)

    2010-07-01

    .... 1.105 Section 1.105 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE... literature, published application, or patent (U.S. or foreign), by any of the inventors, that relates to the claimed invention. (iv) Information used to draft application: A copy of any non-patent literature...

  8. Complexation de l'aluminium par des hétéropolyanions lacunaires ...

    African Journals Online (AJOL)

    L'objectif visé par cette étude est la dépollution des eaux à partir de la complexation d'un métal toxique, l'aluminium en solution, par des hétéropolyanions lacunaires (HPA) de type Dawson. Les complexes formés sont récupérés par membrane liquide émulsionnée (MEL).Les résultats de la complex1ation de l'aluminium ...

  9. 46 CFR 105.45-1 - Loading or dispensing petroleum products.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Loading or dispensing petroleum products. 105.45-1... VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Special Operating Requirements § 105.45-1 Loading or dispensing petroleum products. (a) A commercial fishing vessel must have aboard a letter of...

  10. 32 CFR 37.1035 - How do I know if my TIA uses the 10 U.S.C. 2371 authority and I must report additional data under...

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false How do I know if my TIA uses the 10 U.S.C. 2371... TIA uses the 10 U.S.C. 2371 authority and I must report additional data under § 37.1030(b)? As explained in appendix B to this part, a TIA uses the authority of 10 U.S.C. 2371 and therefore must be...

  11. 48 CFR 47.105 - Transportation assistance.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Transportation assistance... MANAGEMENT TRANSPORTATION General 47.105 Transportation assistance. (a) Civilian Government activities that do not have transportation officers, or otherwise need assistance on transportation matters, shall...

  12. evaluation de la fertilite femelle des arabusta par le niveau de ...

    African Journals Online (AJOL)

    Les hybrides Arabusta sont caractérisés par une faible fertilité exprimée par des taux de caracolis élevés et des taux de loges vides importants induisant des productivités faibles. Pour une stratégie plus efficiente des sélections, il est important de connaître les niveaux de fertilité femelle des différents types de caféiers ...

  13. Troubles psychotiques précipités par le mariage : étude de trois observations

    Science.gov (United States)

    Jaweher, Masmoudi; Kammoun, Mohamed Faouzi; Inès, Feki; Imen, Baati; Rim, Sallami; Abdelaziz, Jaoua

    2013-01-01

    Le mariage est un évènement très investi dans notre culture arabo-musulmane. Il présente une situation à grande charge émotionnelle et ayant un vécu stressant. C'est ainsi qu'il peut être à l'origine de la décompensation de certains troubles psychiatriques. Ce moment particulier de déclenchement de la pathologie peut altérer significativement l'adaptation familiale et sociale du patient en question, le rendant dépendant en partie ou en totalité à une institution. Dans ce travail, nous proposons d’étudier certains facteurs psychiques, sociaux et culturels pouvant aboutir à la précipitation des manifestations psychotiques par le mariage. Il s'agit de l’étude de trois observations cliniques, deux hommes et une femme, hospitalisés dans le service de psychiatrie A du CHU Hédi Chaker de Sfax et qui ont développés des manifestations psychotiques de façon concomitante à leur mariage. La durée moyenne de survenue des crises a été de vingt ans, le diagnostic retenu a été celui de trouble bipolaire dans deux cas et d'une schizophrénie indifférenciée chez le troisième patient. L’évolution s'est faite vers une chronicisation de deux malades et une dépendance institutionnelle dans le troisième cas. La précipitation des troubles psychotiques par le mariage, reste un phénomène en relation intime avec les composantes culturelles, elles-mêmes sont déterminantes dans la prise en charge ultérieure de ces patients. PMID:23785551

  14. Etudes phytochimique et pharmacologique de Bridelia ferruginea ...

    African Journals Online (AJOL)

    L'extrait aqueux de Bridelia ferruginea provoque entre 10-5mg/mL et 10-1mg/mL une augmentation des contractions rythmiques de muscle lisse Taenia coli de cobaye. Ces effets inotropes positifs antagonisés par l'Atropine (10-6mg/mL) sont totalement abolis en milieu pauvre (0Ca2+) et dépourvus de calcium (0Ca2++ ...

  15. Serum Level of a Soluble Form of Endoglin (CD105 is Decreased after Goeckerman’s Therapy of Psoriasis

    Directory of Open Access Journals (Sweden)

    David Pohl

    2011-01-01

    Full Text Available Background. Goeckerman’s therapy (GT of psoriasis is based on daily application of pharmacy grade coal tar on affected skin with subsequent exposure to UV light. Disturbances in angiogenic activity are characteristic for the immunopathogenesis of psoriasis. The aim of study was to evaluate the influence of GT of psoriasis on proinflammatory and angiogenic activities expressed as changes in levels of endoglin (CD105. Methods. Serum levels of a soluble form of endoglin were measured in peripheral blood samples of 38 patients with psoriasis before and after therapy. Sixty three otherwise healthy blood donors serve as a control group. The efficacy of GT was expressed as changes in Psoriasis Area and Severity Index (PASI. Results. PASI score was significantly diminished by GT (p<0.001. Serum levels of soluble CD105 were significantly diminished after GT. The serum level of soluble CD105 dropped from 7.85 ± 2.26 ng/ml before therapy to 7.01 ± 1.71 ng/ml after therapy (p= 0.0002. Compared to serum levels of soluble CD105 in healthy blood donors, serum levels of soluble CD105 in patients before GT were significantly higher (p<0.001 and remained elevated after therapy (p<0.001. Angiogenic activity expressed as serum endoglin is diminished in patients with psoriasis treated by GT.

  16. 46 CFR 111.105-17 - Wiring methods for hazardous locations.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Wiring methods for hazardous locations. 111.105-17... ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Hazardous Locations § 111.105-17 Wiring methods for... made with dust-tight cable entrance seals approved for the installation. [CGD 94-108, 61 FR 28284, June...

  17. Dual Role of Host Par2 in a Murine Model of Spontaneous Metastatic B16 Melanoma

    Czech Academy of Sciences Publication Activity Database

    Olejár, Tomáš; Větvička, D.; Zadinová, M.; Poučková, P.; Kukal, J.; Ježek, Petr; Matěj, R.

    2014-01-01

    Roč. 34, č. 7 (2014), s. 3511-3515 ISSN 0250-7005 R&D Projects: GA ČR(CZ) GAP302/10/0346 Institutional support: RVO:67985823 Keywords : PAR2 * melanoma * metastasis * murine model Subject RIV: EA - Cell Biology Impact factor: 1.826, year: 2014

  18. 23 CFR 500.105 - Requirements.

    Science.gov (United States)

    2010-04-01

    ... HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRANSPORTATION INFRASTRUCTURE MANAGEMENT MANAGEMENT AND MONITORING SYSTEMS Management Systems § 500.105 Requirements. (a) The metropolitan transportation planning process (23 U.S.C. 134 and 49 U.S.C. 5303-5005) in TMAs shall include a CMS that meets the...

  19. 48 CFR 46.105 - Contractor responsibilities.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contractor... CONTRACT MANAGEMENT QUALITY ASSURANCE General 46.105 Contractor responsibilities. (a) The contractor is..., and furnishing such information to the Government as required. (b) The contractor may be required to...

  20. MANAGEMENT BOARD OF 21 MAY 07 (MB105)

    CERN Multimedia

    LHC The modifications to one set of quadrupoles of an inner triplet should be completed in early June, followed by the next pressure test. There would be a meeting between the CERN Director General and Deputy and the LHC Project Leader soon and it was expected to receive information on the outcome shortly thereafter. There was not expected to be a change of date of the scheduled LHC start-up around the end of April 2008. LHCC The committee had been generally pleased with the progress, and had been impressed by a sea change in that of the HLT. Computing appeared to be in good shape and the prospective shift of physics analysis work from T1s to T2s welcomed. It had also been noted that there was attention to future issues such as potential single point failures. A number of problems had been identified in time for remedial action. An example was catching the faulty wiring of all barrel RPC HV cables, all of which would need to be replaced. The main concern remained with the schedule for YB0 services ins...

  1. ParA and ParB coordinate chromosome segregation with cell elongation and division during Streptomyces sporulation

    Science.gov (United States)

    Donczew, Magdalena; Mackiewicz, Paweł; Wróbel, Agnieszka; Flärdh, Klas; Zakrzewska-Czerwińska, Jolanta

    2016-01-01

    In unicellular bacteria, the ParA and ParB proteins segregate chromosomes and coordinate this process with cell division and chromosome replication. During sporulation of mycelial Streptomyces, ParA and ParB uniformly distribute multiple chromosomes along the filamentous sporogenic hyphal compartment, which then differentiates into a chain of unigenomic spores. However, chromosome segregation must be coordinated with cell elongation and multiple divisions. Here, we addressed the question of whether ParA and ParB are involved in the synchronization of cell-cycle processes during sporulation in Streptomyces. To answer this question, we used time-lapse microscopy, which allows the monitoring of growth and division of single sporogenic hyphae. We showed that sporogenic hyphae stop extending at the time of ParA accumulation and Z-ring formation. We demonstrated that both ParA and ParB affect the rate of hyphal extension. Additionally, we showed that ParA promotes the formation of massive nucleoprotein complexes by ParB. We also showed that FtsZ ring assembly is affected by the ParB protein and/or unsegregated DNA. Our results indicate the existence of a checkpoint between the extension and septation of sporogenic hyphae that involves the ParA and ParB proteins. PMID:27248800

  2. 41 CFR 105-68.355 - What information must I provide to a higher tier participant before entering into a covered...

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What information must I...-68.355 Section 105-68.355 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General Services...

  3. Par Pond water balance

    International Nuclear Information System (INIS)

    Hiergesell, R.A.; Dixon, K.L.

    1996-06-01

    A water budget for the Par Pond hydrologic system was established in order to estimate the rate of groundwater influx to Par Pond. This estimate will be used in modeling exercises to predict Par Pond reservoir elevation and spillway discharge in the scenario where Savannah River water is no longer pumped and discharged into Par Pond. The principal of conservation of mass was used to develop the water budget, where water inflow was set equal to water outflow. Components of the water budget were identified, and the flux associated with each was determined. The water budget was considered balanced when inflow and outflow summed to zero. The results of this study suggest that Par Pond gains water from the groundwater system in the upper reaches of the reservoir, but looses water to the groundwater system near the dam. The rate of flux of groundwater from the water table aquifer into Par Pond was determined to be 13 cfs. The rate of flux from Par Pond to the water table aquifer near the dam was determined to be 7 cfs

  4. Speciālistu viedoklis par viedierīču izmantošanu bērnu rotaļās

    OpenAIRE

    Lemko, Laila

    2017-01-01

    Bakalaura darba “Speciālistu viedoklis par viedierīču izmantošanu bērnu rotaļās” mērķis ir noskaidrot, kāds ir bērnu psihologu un videospēļu un lietotņu izstrādātāju viedoklis par viedierīču izmantošanu bērnu rotaļās. Darbs sastāv no četrām nodaļām – divām teorētiskajām, pētījuma metodoloģijas un empīriskā pētījuma analīzes nodaļas, kurai seko pētījuma secinājumi un diskusija. Pētījuma objekts ir bērnu psihologi un bērnu auditorijām paredzēto videospēļu un lietotņu izstrādātāji. Par pētījuma ...

  5. Determination of the sanguine iodine content by activation analysis (1962); Determination de l'iode sanguin par analyse d'activation (1962)

    Energy Technology Data Exchange (ETDEWEB)

    Kellershohn, C; Comar, D; Le Poec, C [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1962-07-01

    Two methods of measuring the iodine content of the blood by activation analysis after 30 min irradiation in a flux of 6.10{sup 12} n/cm{sup 2}.s are described. One method includes a chemical separation of iodine before irradiation. The radioactivity of this specimen is determined on the basis of the amplitude of the iodine 128 photoelectric peak measured by {gamma}-spectrometry. The sensitivity of this method is about 10{sup -8} g. The other includes chemical separation after irradiation, and radioactivity is subsequently measured with a Geiger-Muller counter. The sensitivity of this second method is about 10{sup -10} g, sufficient for determination of the plasmatic mineral content. The advantages of activation analysis over the conventional method based on colorimetric measurement of the catalytic action of iodine in the oxidation of arsenious anhydride with ceric sulphate are discussed. Initial results obtained with this new form of analysis are detailed as are also the possibilities of measuring plasmatic proteic iodine by scintillation spectrometry without prior chemical separation. (authors) [French] Deux methodes de dosage de l'iode sanguin par analyse d'activation apres irradiation de 30 minutes a 6.10{sup 12} n/cm{sup 2} s sont decrites. L'une comprend une separation chimique de l'iode avant l'irradiation et la mesure de la radioactivite est effectuee a partir de l'amplitude du pic photo-electrique de l'iode 128 obtenu par spectrometrie-{gamma}. Sa sensibilite est de l'ordre de 10{sup -8} g. L'autre comprend une separation chimique de l'iode apres l'irradiation et la radioactivite de l'iode-128 est mesuree par comptage-{beta} avec un compteur Geiger. Sa sensibilite est de l'ordre de 10{sup -10} g, permettant d'envisager le dosage de l'iode mineral plasmatique. Les avantages de l'analyse d'activation sur la methode classique, basee sur la mesure colorimetrique de l'action catalytique de l'iode dans l'oxydation de l'anhydride arsenieux par le sulfate cerique

  6. Escala de Estrés y Afrontamiento para familias con hijos afectados de Parálisis Cerebral

    OpenAIRE

    Badia Corbella, Marta; Aguado Díaz, Antonio-León

    2002-01-01

    La evaluación del estrés en las familias con hijos que tienen alguna discapacidad resulta una tarea compleja y difícil. La Escala de Estrés y Afrontamiento para familias con hijos afectados de Parálisis Cerebral (EEAF–PC) ha sido diseñada para dar respuesta a la necesidad de ofrecer un instrumento de medición del estrés para tales familias. La EEAF–PC consta de 42 ítems y el análisis factorial ha proporcionado seis factores: características de la Discapacidad, Protección, Riesgo, Retraso Ment...

  7. Étude par spectroscopie Raman de résonance de composés modèles de la polyaniline

    Science.gov (United States)

    Boyer, M. I.; Quillard, S.; Louarn, G.; Lefrant, S.; Rebourt, E.; Monkman, A.

    1998-06-01

    In this paper, a vibrational study (Resonance Raman Scattering and valence- force-field calculations) of some model compounds of polyaniline is presented. Indeed, this model compound approach allows one to obtain some informations about the vibrational properties and consequently about the electronic configurations of the corresponding polymeric forms. By using valence-force- field calculations, three sets of force constants have been obtained, related to the reduced and oxidized units of the base forms of polyaniline and to the emeraldine salt form. Dans ce travail, nous présentons une étude vibrationnelle (diffusion Raman de résonance et calcul de champ de force de valence) de quelques composés modèles de la polyaniline. Cette approche par les composés modèles permet, en effet, d'obtenir des informations sur les propriétés vibrationnelles et à fortiori sur les configurations électroniques des formes polymères correspondantes. Ainsi, par un calcul de champ de force de valence, trois jeux de constantes ont été déterminés relatifs aux unités réduites et oxydées des différentes formes bases des polyanilines et à la forme éméraldine sel.

  8. Activated protein C (APC) can increase bone anabolism via a protease-activated receptor (PAR)1/2 dependent mechanism.

    Science.gov (United States)

    Shen, Kaitlin; Murphy, Ciara M; Chan, Ben; Kolind, Mille; Cheng, Tegan L; Mikulec, Kathy; Peacock, Lauren; Xue, Meilang; Park, Sang-Youel; Little, David G; Jackson, Chris J; Schindeler, Aaron

    2014-12-01

    Activated Protein C (APC) is an anticoagulant with strong cytoprotective properties that has been shown to promote wound healing. In this study APC was investigated for its potential orthopedic application using a Bone Morphogenetic Protein 2 (rhBMP-2) induced ectopic bone formation model. Local co-administration of 10 µg rhBMP-2 with 10 µg or 25 µg APC increased bone volume at 3 weeks by 32% (N.S.) and 74% (pAPC are largely mediated by its receptors endothelial protein C receptor (EPCR) and protease-activated receptors (PARs). Cultured pre-osteoblasts and bone nodule tissue sections were shown to express PAR1/2 and EPCR. When pre-osteoblasts were treated with APC, cell viability and phosphorylation of ERK1/2, Akt, and p38 were increased. Inhibition with PAR1 and sometimes PAR2 antagonists, but not with EPCR blocking antibodies, ameliorated the effects of APC on cell viability and kinase phosphorylation. These data indicate that APC can affect osteoblast viability and signaling, and may have in vivo applications with rhBMP-2 for bone repair. © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

  9. suPAR

    DEFF Research Database (Denmark)

    Hodges, Gethin W; Bang, Casper N; Wachtell, Kristian

    2015-01-01

    The fundamental role of inflammation in cardiovascular disease (CVD) has prompted interest in numerous biomarkers that detect subclinical levels of inflammation. Soluble urokinase plasminogen activator receptor (suPAR) is a novel biomarker that correlates significantly with cardiovascular events ...... comprehensive review of suPAR in CVD and explore its function and usefulness in predicting cardiovascular events....

  10. SOUTH RAMP DEVIATED ALIGNMENT 3.01.X AREA GROUND SUPPORT ANALYSIS (STATION 71+07.10 TO 71+44.10)

    International Nuclear Information System (INIS)

    M.J. Mrugala

    2000-01-01

    The purpose of the analysis is to provide a basis for ensuring safe conditions in the Case VI area. The scope of this analysis is to analyze and recommend future action for a section of the South Ramp with a deviated alignment, here referred to as Case VI 3.01.X area. This area is located between Stations 71+07.10 to 71+44.10 in the South Ramp of the ESF (Exploratory Studies Facility) Main Loop tunnel. The scope of the analysis includes accomplishing the following goals: (1) Document the as-built configuration including existing voids and installed ground support; (2) Document the geotechnical properties of the rock mass and structural features; and (3) Evaluate the stability and develop recommendations for future action

  11. In vitro activity of five quinolones and analysis of the quinolone resistance-determining regions of gyrA, gyrB, parC, and parE in Ureaplasma parvum and Ureaplasma urealyticum clinical isolates from perinatal patients in Japan.

    Science.gov (United States)

    Kawai, Yasuhiro; Nakura, Yukiko; Wakimoto, Tetsu; Nomiyama, Makoto; Tokuda, Tsugumichi; Takayanagi, Toshimitsu; Shiraishi, Jun; Wasada, Kenshi; Kitajima, Hiroyuki; Fujita, Tomio; Nakayama, Masahiro; Mitsuda, Nobuaki; Nakanishi, Isao; Takeuchi, Makoto; Yanagihara, Itaru

    2015-04-01

    Ureaplasma spp. cause several disorders, such as nongonococcal urethritis, miscarriage, and preterm delivery with lung infections in neonates, characterized by pathological chorioamnionitis in the placenta. Although reports on antibiotic resistance in Ureaplasma are on the rise, reports on quinolone-resistant Ureaplasma infections in Japan are limited. The purpose of this study was to determine susceptibilities to five quinolones of Ureaplasma urealyticum and Ureaplasma parvum isolated from perinatal samples in Japan and to characterize the quinolone resistance-determining regions in the gyrA, gyrB, parC, and parE genes. Out of 28 clinical Ureaplasma strains, we isolated 9 with high MICs of quinolones and found a single parC gene mutation, resulting in the change S83L. Among 158 samples, the ParC S83L mutation was found in 37 samples (23.4%), including 1 sample harboring a ParC S83L-GyrB P462S double mutant. Novel mutations of ureaplasmal ParC (S83W and S84P) were independently found in one of the samples. Homology modeling of the ParC S83W mutant suggested steric hindrance of the quinolone-binding pocket (QBP), and de novo prediction of peptide structures revealed that the ParC S84P may break/kink the formation of the α4 helix in the QBP. Further investigations are required to unravel the extent and mechanism of antibiotic resistance of Ureaplasma spp. in Japan. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  12. O ensino de língua materna através de paródias como ferramenta educacional

    Directory of Open Access Journals (Sweden)

    Rafael de Souza Velasco

    2017-12-01

    Full Text Available O presente trabalho apresenta uma pesquisa empírica que visou refletir sobre a importância do ensino lúdico de língua portuguesa, através da implantação de paródias como ferramenta educacional na escola pública. Este trabalho teve por parâmetro a Lei 13.278/2016, que inclui as artes visuais, a dança, a música e o teatro nos currículos dos diversos níveis da educação básica. De base da legislação realizamos uma reflexão sobre o ensino de música na escola como um instrumento auxiliar do professor no processo de ensino e de aprendizagem dos alunos se apropriando da composição de paródias como recurso pedagógico na área da Linguagem.  Defendemos a ideia de que o material criativo imprime dinamicidade ao conteúdo didático, promovendo interesse e despertando a curiosidade. A orientação metodológica utilizada é um estudo de caso de cunho descritivo qualitativo, que tem relação com a área de educação, da qual se refere, a contribuição de paródias musicais no ensino aprendizagem de alunos. A pesquisa foi realizada em duas escolas públicas da cidade de Pelotas, escolas estas situadas em diferentes localizações da cidade e uma sendo da Rede Estadual e outra da Rede Municipal. Os informantes foram os alunos do sétimo ano do Ensino Fundamental. Verificamos que a música, neste contexto, pode se configurar em um fortíssimo aliado mnemônico para a compreensão das regras de língua portuguesa, bem como para a formação do sujeito em virtude de se configurar em uma linguagem. A ludicidade se configura em um reforço pedagógico, ajudando os alunos na compreensão, memorização, oralidade, criatividade e, desta forma, resultando em um mecanismo de ensino e de aprendizagem mais eficaz.

  13. Intercellular communications within the rat anterior pituitary. XVI: postnatal changes of distribution of S-100 protein positive cells, connexin 43 and LH-RH positive sites in the pars tuberalis of the rat pituitary gland. An immunohistochemical and electron microscopic study.

    Science.gov (United States)

    Wada, Ikuo; Sakuma, Eisuke; Shirasawa, Nobuyuki; Wakabayashi, Kenjiro; Otsuka, Takanobu; Hattori, Kazuki; Yashiro, Takashi; Herbert, Damon C; Soji, Tsuyoshi

    2014-02-01

    The architecture of luteinizing hormone-releasing hormone (LH-RH) nerve ends and the S-100 protein containing folliculo-stellate cells forming gap junctions in the pars tuberalis is basically important in understanding the regulation of the hormone producing mechanism of anterior pituitary glands. In this study, intact male rats 5-60 days old were prepared for immunohistochemistry and electron microscopy. From immunostained sections, the S-100 containing cells in pars tuberalis were first detected on day 30 and increased in number to day 60; this was parallel to the immunohistochemical staining of gap junction protein, connexin 43. LH-RH positive sites were clearly observed on just behind the optic chiasm and on the root of pituitary stalk on day 30. On day 60, the width of layer increased, while follicles and gap junctions were frequently observed between agranular cells in 10 or more layers of pars tuberalis. In the present study, we investigated the sexual maturation of the anterior pituitary glands through the postnatal development of S-100 positive cells, connexin 43 and LH-RH nerves. It is suggested that the folliculo-stellate cell system including the LH-RH neurons in the pars tuberalis participates in the control of LH secretion along with the portal vein system. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. 7 CFR 1463.105 - Base quota levels for eligible quota holders.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Base quota levels for eligible quota holders. 1463.105 Section 1463.105 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY... TRANSITION PROGRAM Tobacco Transition Payment Program § 1463.105 Base quota levels for eligible quota holders...

  15. Evaluation of sustainability in the use of water within the Amazon deforestation area: a case study in Rondon do Pará, Pará State, Brazil - doi: 10.4025/actascitechnol.v35i2.13820

    Directory of Open Access Journals (Sweden)

    Augusto da Gama Rego

    2013-04-01

    Full Text Available The use of water in a hydrographic basin within the Amazon deforestation area is evaluated as a case study for the municipality of Rondon do Pará, State of Pará, Brazil. Current investigation takes into account the hydrographic basin as a system, following the Pressure/State/Response concept model, and aims at an analysis of the system’s sustainability. Results show that the use of water within the context of the system under analysis tends towards non-sustainability. Economic growth, especially triggered by the expansion of extensive cattle-raising and industrial activities, has worsened the situation. These conditions do not represent local reality since the above-mentioned activities have produced only scanty employment. Further, the municipality is striving with problems concerning the supply of drinking water, deficiency in sewage treatment and especially the deterioration of surface water resources.  

  16. 48 CFR 2909.105 - Procedures.

    Science.gov (United States)

    2010-10-01

    ... determination of contractor responsibility on a review of the company's “Summary or Financial Report” from Dun...'s responsibility in accordance with FAR 9.105. In addition to past performance information, the...

  17. Proteinase-Activated Receptor-1 and Immunomodulatory Effects of a PAR1-Activating Peptide in a Mouse Model of Prostatitis

    Science.gov (United States)

    Stanton, M. Mark; Nelson, Lisa K.; Benediktsson, Hallgrimur; Hollenberg, Morley D.; Buret, Andre G.; Ceri, Howard

    2013-01-01

    Background. Nonbacterial prostatitis has no established etiology. We hypothesized that proteinase-activated receptor-1 (PAR1) can play a role in prostatitis. We therefore investigated the effects of PAR1 stimulation in the context of a new model of murine nonbacterial prostatitis. Methods. Using a hapten (ethanol-dinitrobenzene sulfonic acid- (DNBS-)) induced prostatitis model with both wild-type and PAR1-null mice, we examined (1) the location of PAR1 in the mouse prostate and (2) the impact of a PAR1-activating peptide (TFLLR-NH2: PAR1-TF) on ethanol-DNBS-induced inflammation. Results. Ethanol-DNBS-induced inflammation was maximal at 2 days. In the tissue, PAR1 was expressed predominantly along the apical acini of prostatic epithelium. Although PAR1-TF on its own did not cause inflammation, its coadministration with ethanol-DNBS reduced all indices of acute prostatitis. Further, PAR1-TF administration doubled the prostatic production of interleukin-10 (IL-10) compared with ethanol-DNBS treatment alone. This enhanced IL-10 was not observed in PAR1-null mice and was not caused by the reverse-sequence receptor-inactive peptide, RLLFT-NH2. Surprisingly, PAR1-TF, also diminished ethanol-DNBS-induced inflammation in PAR1-null mice. Conclusions. PAR1 is expressed in the mouse prostate and its activation by PAR1-TF elicits immunomodulatory effects during ethanol-DNBS-induced prostatitis. However, PAR1-TF also diminishes ethanol-DNBS-induced inflammation via a non-PAR1 mechanism by activating an as-yet unknown receptor. PMID:24459330

  18. Electron microscope study of vacancy clusters produced by quenching in magnesium; Etude par microscopie electronique des amas de lacunes crees par trempe dans le magnesium

    Energy Technology Data Exchange (ETDEWEB)

    Levy, V; Espinasse, J; Mairy, C; Hillairet, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-07-01

    Vacancy clustering in quenched magnesium has been studied by transmission electron microscopy. The nature of the vacancy loops observed, seems to depend essentially on the impurity content of the metal; this effect can be attributed to a variation of the stacking fault energy of magnesium due to impurities. (authors) [French] On a etudie par microscopie electronique en transmission les defauts crees par trempe dans le magnesium. Un effet considerable des impuretes du metal sur la nature des boucles obtenues par condensation de lacunes a ete mis en evidence; cet effet semble s'expliquer de facon satisfaisante par un abaissement de l'energie de faute d'empilement du magnesium du aux impuretes. (auteur)

  19. 27 CFR 10.1 - General.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false General. 10.1 Section 10.1... TREASURY LIQUORS COMMERCIAL BRIBERY Scope of Regulations § 10.1 General. The regulations in this part, issued pursuant to section 105 of the Federal Alcohol Administration Act (27 U.S.C. 205), specify...

  20. Memory and Nostalgia in Woody Allen’s "Midnight in Paris" (Memoria y nostalgia en "Medianoche en París" de Woody Allen

    Directory of Open Access Journals (Sweden)

    Peter Eubanks

    2015-06-01

    Full Text Available Abstract: Woody Allen´s recent "Midnight in Paris" describes a Paris that has as many identities as there are observers to ascribe them. Indeed, there is no one, true Paris that everyone objectively shares; Paris, in Allen´s film, exists only in the phenomenology of the observer’s perception, a perception often marred and made unreliable by an escapist need to withdraw from the present in order to take shelter in a glorified, utopian past. Allen thus criticizes the nostalgic impulse, the "Golden-Age thinking" (as it is called in the film that forces various characters simultaneously to inhabit two worlds, that of a prelapsarian past and that of the fallen present. His protagonist´s journey back and forth between the present and the idealized Roaring Twenties is everyman´s journey, the sometimes surreal voyage between reality and imagination, between the world actually inhabited and the world artificially constructed for oneself. Yet it is when Allen´s protagonist finally discovers nostalgia within his nostalgia, a longing within his longing, that he recognizes the flawed thinking behind his almost mythologized perception of the past, reflecting everyman´s realization that the past is ultimately the expression of our present needs.Resumen: Uno de los films recientes de Woody Allen, "Midnight in Paris", describe un París que tiene tantas identidades como observadores hay a quienes atribuirlos. De hecho, no hay un París auténtico que compartan todos. París, en el film de Allen, solo existe en la fenomenología de la percepción del observador, una percepción con frecuencia dañada/arruinada y realizada poco fidedigna por una necesidad escapista a retirarse del presente para refugiarse en un pasado glorificado, utópico. Así Allen critica el impulso nostálgico, la idea del "pensamiento del siglo de oro" (tal y como viene a ser llamado en el film que obliga a que varios personajes residan en dos mundos al mismo tiempo: el de un mundo

  1. Universidad de saint-denis parís 8: polo de desarrollo territorial

    Directory of Open Access Journals (Sweden)

    Iván Segura Lara

    2013-04-01

    Full Text Available El proyecto Universidad, arte y territorio tiene su origen en los archivos fotográficos en torno a laevolución arquitectónica de la universidad de Saint-Denis París-8 que durante 15 años, asociadoa un equipo de investigadores, alimentó el autor, para desarrollar un enfoque transdisciplinarioque analizara el papel de las entidades culturales como motor de las transformaciones territorialeslocales. Se formularon criterios para la creación de laboratorios internacionales de observación delterritorio y análisis de las fuerzas de la globalización que condicionan estas transformaciones. Apartir de esto se infirieron nuevas nociones para definir los criterios de ciudad contemporánea bajolos nuevos paradigmas de la globalización. Simultáneamente, los procesos de documentación yrepresentación construyen a través de su doble especificidad científica y estética un conocimientoy una poesía sensible a los procesos de construcción de la historia de la universidad.

  2. Parálisis cerebral :

    OpenAIRE

    Cabrero Izquierdo, María del Carmen

    2012-01-01

    Se aborda el tema de la parálisis cerebral definiendo qué es, clasificando los tipos de parálisis dependiendo de la afectación y las características principales. Se explican algunos de sus tratamientos, se dan sistemas alternativos y/o aumentativos de comunicación para un alumno con PC (parálisis cerebral).

  3. L'analyse par activation de neutrons de réacteur

    Science.gov (United States)

    Meyer, G.

    2003-02-01

    Quand les neutrons traversent la matière, certains sont transmis sans interaction, les autres interagissent avec le milieu traversé par diffusion et par absorption. Ce phénomène d'absorption est utilisé pour se protéger des neutrons, mais aussi pour les détecter; il peut également être utilisé pour identifier les noyaux “absorbants" et ainsi analyser le milieu traversé. En effet par différentes réactions nucléaires (n,γ), (n,p), (n,α), (n,fission), on obtient des noyaux résiduels qui sont souvent radioactifs; on dit que l'échantillon est “activé". Si l'on connaît le rendement d'activation et donc le pourcentage de noyaux ainsi “transmutés", les mesures de radioactivité induite vont permettre de déterminer la composition de l'échantillon irradié. Cette méthode dite d'analyse par activation neutronique est pratiquée depuis la découverte du neutron. Elle a permis grâce à sa sélectivité et à sa sensibilité d'avoir accès au domaine des traces et des ultra-traces dans des champs d'application très divers comme la métallurgie, l'archéologie, la biologie, la géochimie etc...

  4. mTORC2 activation is regulated by the urokinase receptor (uPAR) in bladder cancer.

    Science.gov (United States)

    Hau, Andrew M; Leivo, Mariah Z; Gilder, Andrew S; Hu, Jing-Jing; Gonias, Steven L; Hansel, Donna E

    2017-01-01

    Mammalian target of rapamycin complex 2 (mTORC2) has been identified as a major regulator of bladder cancer cell migration and invasion. Upstream pathways that mediate mTORC2 activation remain poorly defined. Urokinase-type plasminogen activator receptor (uPAR) is a GPI-anchored membrane protein and known activator of cell-signaling. We identified increased uPAR expression in 94% of invasive human bladder cancers and in 54-71% of non-invasive bladder cancers, depending on grade. Normal urothelium was uPAR-immunonegative. Analysis of publicly available datasets identified uPAR gene amplification or mRNA upregulation in a subset of bladder cancer patients with reduced overall survival. Using biochemical approaches, we showed that uPAR activates mTORC2 in bladder cancer cells. Highly invasive bladder cancer cell lines, including T24, J82 and UM-UC-3 cells, showed increased uPAR mRNA expression and protein levels compared with the less aggressive cell lines, UROtsa and RT4. uPAR gene-silencing significantly reduced phosphorylation of Serine-473 in Akt, an mTORC2 target. uPAR gene-silencing also reduced bladder cancer cell migration and Matrigel invasion. S473 phosphorylation was observed by immunohistochemistry in human bladder cancers only when the tumors expressed high levels of uPAR. S473 phosphorylation was not controlled by uPAR in bladder cancer cell lines that are PTEN-negative; however, this result probably did not reflect altered mTORC2 regulation. Instead, PTEN deficiency de-repressed alternative kinases that phosphorylate S473. Our results suggest that uPAR and mTORC2 are components of a single cell-signaling pathway. Targeting uPAR or mTORC2 may be beneficial in patients with bladder cancer. Copyright © 2016. Published by Elsevier Inc.

  5. SECHAGE DE PRODUITS GRANULAIRES PAR DESHYDRATATION PAR DETENTES SUCCESSIVES (DDS)

    OpenAIRE

    Abdulla , Galal; Mellouk , Hamid; Belghit , Abdelhamid; Allaf , Karim

    2009-01-01

    International audience; Dans cette étude, nous avons évalué les performances d'un nouveau procédé de séchage dans le cas du liège en granulés. Ce procédé (La déshydratation par détentes successives : DDS) consiste à soumettre le matériau liège dans une chambre hermétique aux variations cycliques de la pression. Chaque cycle est composé d'une compression et d'une décompression. La phase de compression est réalisée en injectant de l'air comprimé à température ambiante provenant d'un compresseur...

  6. El Acuerdo de París. Predominio del soft law en el régimen climático

    OpenAIRE

    Nava Escudero, César

    2016-01-01

    Resumen Es práctica común entre los Estados, adoptar dentro del régimen internacional de protección al ambiente, al que pertenece el régimen climático, acuerdos vinculantes con un alto contenido de normas que carecen de obligatoriedad; esto es, normas de soft law. El Acuerdo de París de 2015 es precisamente un ejemplo de lo anterior. A través de un breve análisis del contenido soft en los dos antecedentes convencionales más importantes (es decir, la Convención Marco de las Naciones Unidas sob...

  7. Chemical analysis of rainfall and throughfall in primary forest in the Tapajós National Forest, Belterra, Pará, Brazil

    Science.gov (United States)

    R.C. Oliveira Junior; M. Keller; J. F. da F. Ramos; T.P. Beldini; P.M Crill; P.B. de Camargo; J. van Haren

    2015-01-01

    The Tapajós National Forest (FLONA Tapajós) has 600,000 hectares of protected forest, and is situated 50 km south of the city of Santarém, Pará, Brazil, a port city of 250,000 inhabitants that is located at the confluence of the Tapajós and Amazon Rivers. There is a lot of farmland in the region, which offers many opportunities to study changes in land use. Selective...

  8. Effect of simvastatin and ezetimibe on suPAR levels and outcomes

    DEFF Research Database (Denmark)

    Hodges, Gethin W; Bang, Casper N; Forman, Julie L

    2018-01-01

    -lowering therapy also lowers suPAR levels is unknown. METHODS: We investigated whether treatment with Simvastatin 40 mg and Ezetimibe 10 mg lowered plasma suPAR levels in 1838 patients with mild-moderate, asymptomatic aortic stenosis, included in the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) study, using...... and Ezetimibe treatment impeded the progression of the time-related increase in plasma suPAR levels. Year-1 suPAR was associated with all-cause mortality, MCE, and AVE irrespective of baseline levels (SEAS study: NCT00092677)....... cardiovascular events (MCE) composed of ischemic cardiovascular events (ICE) and aortic valve related events (AVE). RESULTS: After 4.3 years of follow-up, suPAR levels had increased by 9.2% (95% confidence interval [CI]: 7.0%-11.5%) in the placebo group, but only by 4.1% (1.9%-6.2%) in the group with lipid...

  9. Un « gouvernement des journalistes par le Pouvoir politique » par défaut ?

    Directory of Open Access Journals (Sweden)

    Matthieu Lardeau

    2013-12-01

    Full Text Available Cet article présente les interactions de deux mouvements concomitants apparusprincipalement dans les décennies 1950 à 1970 dans le champ de la presse française : d’un côté les initiatives – consécutives à la démarche pionnière, en 1951, de création de la première Société des journalistes (SDJ au sein du Monde – menées par les journalistes de rédactions de quotidiens pour créer des SDJ dont la destination peut aller jusqu’à gouverner les journaux; de l’autre côté, les « réponses » apportées par les Pouvoirs politique et public pour contenir ces initiatives visant à étendre le pouvoir des journalistes dans la gestion et la gouvernance de leurs journaux. Cette étude exploratoire repose principalement sur l’analyse de deux types de littérature, souvent déconsidérés ou négligés par le champ académique, en dépit de leur grande richesse : (1 la littérature professionnelle, ayant pour principaux auteurs les journalistes et managers de presse (Périer Daville, Boegner, Pigasse, etc., florissante depuis 1944 et singulièrement durant les décennies 1960 et 1970 ; (2 la littérature grise constituée notamment par des rapports publics rédigés par des institutions comme les services du Premier ministre (commissions Lindon de 1970 et Serisé de 1972, le Conseil économique et social, etc. Nos principaux résultats montrent que les propositions ou actions menées par les journalistes (1 restent le plus souvent inexploitées in concreto par les journalistes eux-mêmes; (2 entrent le plus souvent en opposition avec les politiques de nouveaux actionnaires ou directions de journaux et avec les projets des autorités politiques et publiques qui cherchent à encadrer l’autonomie de la profession journalistique pour mieux gouverner celle-ci ; (3 combien in fine les représentants des différents acteurs impliqués s’accordent pour contenir l’émergence d’un « gouvernement des journalistes » par les

  10. Engineering evaluation/cost analysis for the 105-DR and 105-F Reactor facilities and ancillary facilities

    International Nuclear Information System (INIS)

    Coenenberg, E.T.

    1998-01-01

    This document presents the results of an engineering evaluation/cost analysis (EE/CA) that was conducted to evaluate alternatives to address final disposition of the 105-DR and 105-F Reactor Buildings (subsequently referred to as facilities), including the fuel storage basins (FSB) and below-grade portions of the reactors, excluding the reactor blocks. The reactor blocks will remain in a safe storage mode for up to 75 years as identified in the Record the Decision (ROD) (58 FR 48509) for the Environmental Impact Statement (EIS), Decommissioning of Eight Surplus Production Reactors at the Hanford Site, Richland, Washington (DOE 1992a). This EE/CA also addresses final disposition of four ancillary facilities: 116-D and 116-DR Exhaust Air Stacks, 117-DR Exhaust Filter Building, and 119-DR Exhaust Air Sample Building. The 105-DR and 105-F facilities are located in the 100-D and 100-F Areas of the Hanford Site. In November 1989, the 100 Area of the Hanford Site was placed on the U.S. Environmental Protection Agency's (EPA) National Priorities List (NPL) under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). The 100 Area NPL includes the 100-D Area (which includes the 100-DR site) and the 100-F Area, which are in various stages of the remediation process. It has been determined by DOE that hazardous substances in the 105-DR, 105-F, and the four ancillary facilities may present a potential threat to human health or the environment, and that a non-time critical removal action at these facilities is warranted. To help determine the most appropriate action, DOE, in cooperation with the Washington State Department of Ecology (Ecology) and the EPA, has prepared this EE/CA. The scope of the evaluation includes the 105-DR and 105-F facilities and the four ancillary facilities. The 116-DR and 117-DR facilities are located within the boundaries of the 105-DR Large Sodium Fire Facility Treatment, Storage, and Disposal (TSD) unit, which is

  11. El enlucido exterior de yeso en las rehabilitaciones de las fachadas de París

    Directory of Open Access Journals (Sweden)

    Raymond Pigache, M.

    1986-07-01

    Full Text Available The use, the manufacture, the putting into excution of gypsum plaster on old Paris façades -a marely manual technique- are specified since long ago. A number of gypsum plaster carried out under Louis the 14th reign, have still a good behaviour in spite of, as it is well known, gypsum in the outside is very sensible to dissolution. This study allows to clarify four fundamental parameters, and its conclusions make it possible to carry out rehabilitations both in prestigeous and in humble buildings: - The use of a mortar which components will be similar to those old materials; - A merely handwork. - An established proportion with a view to protect the gypsum plasters, cornices, moldings, etc. from drainage waters. - Bearing walls with higher mechanical characteristics than those of platers.La utilización, fabricación y puesto en obra de morteros de yeso, sobre las fachadas antiguas en el viejo París -técnica puramente manual-, están precisadas desde hace mucho tiempo. Numerosos enlucidos de mortero de yeso, realizados bajo el reinado de Luis XIV, presentan todavía un excelente comportamiento a pesar de que, como es sabido, el yeso en exteriores es muy sensible a disolverse. Este estudio ha permitido aclarar cuatro parámetros fundamentales y, sobre todo, sus conclusiones han permitido la realización de numerosas rehabilitaciones, tanto en inmuebles de prestigio como en edificaciones modestas: - El empleo de un mortero cuyos componentes sean más cercanos a los materiales antiguos. - Una aplicación puramente manual. - Una proporción establecida a fin de proteger de las aguas de desagüe los enlucidos de mortero de yeso, las cornisas, molduras y etc. - Muros portantes con las características mecánicas más elevadas que las de los enlucidos.

  12. Contribution de la tomographie par coherence optique au diagnostic ...

    African Journals Online (AJOL)

    Contribution de la tomographie par coherence optique au diagnostic de la neuropathie optique toxique. C.O.A. Abouki, S Alamou, C.R.A. Assavedo, L Odoulami-Yehouessi, I Sounouvou, S Hounnou-Tchabi ...

  13. Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4).

    Science.gov (United States)

    Cunningham, Margaret R; McIntosh, Kathryn A; Pediani, John D; Robben, Joris; Cooke, Alexandra E; Nilsson, Mary; Gould, Gwyn W; Mundell, Stuart; Milligan, Graeme; Plevin, Robin

    2012-05-11

    Proteinase-activated receptors 4 (PAR(4)) is a class A G protein-coupled receptor (GPCR) recognized through the ability of serine proteases such as thrombin and trypsin to mediate receptor activation. Due to the irreversible nature of activation, a fresh supply of receptor is required to be mobilized to the cell surface for responsiveness to agonist to be sustained. Unlike other PAR subtypes, the mechanisms regulating receptor trafficking of PAR(4) remain unknown. Here, we report novel features of the intracellular trafficking of PAR(4) to the plasma membrane. PAR(4) was poorly expressed at the plasma membrane and largely retained in the endoplasmic reticulum (ER) in a complex with the COPI protein subunit β-COP1. Analysis of the PAR(4) protein sequence identified an arginine-based (RXR) ER retention sequence located within intracellular loop-2 (R(183)AR → A(183)AA), mutation of which allowed efficient membrane delivery of PAR(4). Interestingly, co-expression with PAR(2) facilitated plasma membrane delivery of PAR(4), an effect produced through disruption of β-COP1 binding and facilitation of interaction with the chaperone protein 14-3-3ζ. Intermolecular FRET studies confirmed heterodimerization between PAR(2) and PAR(4). PAR(2) also enhanced glycosylation of PAR(4) and activation of PAR(4) signaling. Our results identify a novel regulatory role for PAR(2) in the anterograde traffic of PAR(4). PAR(2) was shown to both facilitate and abrogate protein interactions with PAR(4), impacting upon receptor localization and cell signal transduction. This work is likely to impact markedly upon the understanding of the receptor pharmacology of PAR(4) in normal physiology and disease.

  14. Autoridade médica e divulgação científica no Grão-Pará flagelado pelo cólera: século XIX

    Directory of Open Access Journals (Sweden)

    Jane Felipe Beltrão

    2002-06-01

    Full Text Available O incremento da epidemia do cólera, em 1855, no Grão-Pará, desencadeou acirrada polêmica entre os doutores da Província em torno de instruções e tratamentos a serem observados pelos enfermos. Em meio à contenda acadêmica surgiram, através da imprensa, instruções e guias médicos que auxiliaram sobremaneira no combate à epidemia. Os documentos divulgados revelam a capacidade pedagógica e persuasiva dos profissionais de saúde. No Grão-Pará, as vozes eram ouvidas através do Treze de Maio e do Diario do Gram-Pará. Já no Rio de Janeiro, capital do Império do Brasil, os contendedores utilizavam as páginas do Jornal do Commercio e do Diario do Rio de Janeiro. O trabalho apresenta a trama da divulgação científica apoiada na autoridade médica dos profissionais que atuavam no Grão-Pará flagelado pelo cólera.The increment of the Cholera epidemic in 1855 in Grão-Pará started a strong debate among the doctors of the Province regarding the conduct and treatment for the sick. Besides the academic discussion, therapeutical information was largely published in the local press. The documents appearing in the newspapers reveal a pedagogical and persuasive nature. In the Grão-Pará, voices of such nature were heard in the Treze de Maio and in the Diario do Gram Pará. in Rio, the capital of the Empire at the time, the debate took place in the pages of Jornal do Commercio and the Diario do Rio de Janeiro. The paper presents the efforts of science writing based on medical authority of the professionals at work during the Cholera epidemis in Grão-Pará.

  15. 39 CFR 10.1 - Applicability.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Applicability. 10.1 Section 10.1 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE RULES OF CONDUCT FOR POSTAL SERVICE GOVERNORS (ARTICLE X) § 10.1 Applicability. This part contains rules of conduct for the...

  16. 22 CFR 40.105 - Former citizens who renounced citizenship to avoid taxation.

    Science.gov (United States)

    2010-04-01

    ... avoid taxation. 40.105 Section 40.105 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING... Miscellaneous § 40.105 Former citizens who renounced citizenship to avoid taxation. An alien who is a former... avoid United States taxation, is ineligible for a visa under INA 212(a)(10)(E). [62 FR 67568, Dec. 29...

  17. Measurement of the ${B^0_s \\to \\phi \\phi}$ branching fraction and angular analysis of ${B^0_{(s)} \\to \\phi \\pi^{+}\\pi^{-}}$.

    CERN Multimedia

    Morris, Adam

    2016-01-01

    Using 3~fb$^{-1}$ of $pp$ collisions collected by the LHCb detector at $\\sqrt{s} = 7$ and 8~TeV, the $B_s^0 \\to \\phi \\phi$ branching fraction is measured to be \\[ \\mathcal{B}(B^0_s \\to \\phi \\phi) = \\left[ 1.84 \\pm 0.05 (\\mathrm{stat}) \\pm 0.07 (\\mathrm{syst}) \\pm 0.11 (f_s/f_d) \\pm 0.12 (\\mathrm{norm}) \\right] \\times 10^{-5}. \\] A search for the decay $B^0 \\to \\phi \\phi$ is also made. No signal is observed, and an upper limit on the branching fraction is set as \\[ \\mathcal{B}(B^0 \\to \\phi \\phi) < 2.8 \\times 10^{-8}. \\] The rare decays $B_s^0 \\to \\phi \\pi^+ \\pi^-$ and $B^0 \\to \\phi \\pi^+ \\pi^-$ are observed for the first time. The branching fractions in the range $400s^0 \\to \\phi \\pi^+ \\pi^-) = \\left[ 3.37 \\pm 0.20 (\\mathrm{stat}) \\pm 0.16 (\\mathrm{syst}) \\pm 0.34 (\\mathrm{norm}) \\right] \\times 10^{-6} \\] \\[\\mathcal{B}(B^0 \\to \\phi \\pi^+ \\pi^-) = \\left[ 1.58 \\pm 0.18 (\\mathrm{stat}) \\pm 0.35 (\\mathrm{syst}) \\pm 0.13 (\\mathrm{norm})...

  18. Etat nutritionnel des enfants âgés de 6 à 59 mois infectés par le VIH mais non traités aux ARV à Lubumbashi

    Science.gov (United States)

    Mwadianvita, Costa Kazadi; Kanyenze, Faustin Ngoy; Wembonyama, Cecile Watu; Mutomb, Florence Mujing A; Mupoya, Kalombo; Nkoy, Albert Mwembo–Tambwe A; Mwenze, Prosper Kalenga

    2014-01-01

    Introduction L'infection par le VIH provoque et/ou aggrave les déficits nutritionnels de l'enfant. Ce travail avait pour objectif d'analyser l’état nutritionnel des enfants infectés par le VIH à Lubumbashi. Méthodes Une étude transversale portant sur 83 enfants âgés de 6 à 60 mois s'est déroulée de mai 2010 à mai 2011 dans trois(3) centres de prise en charge des Personnes Vivant avec le VIH(PVV), notamment le Centre d'Excellence(CE) de l'hôpital Sendwe, le Centre Amo-Congo de la Kenya et le Centre de Référence de la Kenya. Les statistiques descriptives usuelles ont été utilisées. Résultats La prévalence de la malnutrition globale était de 60,2% (n = 50) dont 8,4% de malnutrition sévère. Le poids moyen était de 11,6±4,1 kg avec un minimum de 5 kg et un maximum de 22 kg. Le taux d'hémoglobine moyen était d'environ 9,8± 2,0 g/dl avec une prévalence globale de l'anémie (hémoglobine VIH. La survenue de l'anémie n’était pas associée au déficit nutritionnel (p = 0,6). Conclusion Ces résultats révèlent que l'infection à VIH modifie l’état nutritionnel des enfants à Lubumbashi avec 60,2% de malnutrition globale et 8,4% de retard de croissance. Les enfants au stade avancé de l'infection à VIH en sont plus affectés. PMID:25574336

  19. Les dispensées par fantaisie en éducation physique et sportive ...

    African Journals Online (AJOL)

    Cette étude vise à comprendre les raisons avancées par les élèves dispensés par fantaisie des cours d'EPS, pour justifier leur attitude et principalement leur forfait. Une enquête par questionnaire écrit a été menée dans 13 établissements publics de la ville de Porto-Novo au Bénin. Au total, 203 élèves parmi les 771 élèves ...

  20. L' Eventrement de París i la configuració del paradigma Aphand-Davioud-Hittorff en el disseny urbà

    Directory of Open Access Journals (Sweden)

    Marie el Haddad

    2017-03-01

    Full Text Available En la primera mitad del siglo XIX y en la Revolución Industrial, ciudades como París se enfrentaron a problemas de salud que les causó el rápido crecimiento de las industrias y las olas de inmigración de las zonas rurales. Como consecuencia, las ciudades, especialmente su centro histórico, sufrieron de congestión, superpoblación e higiene que llevaron a diversas epidemias. Para mejorar las condiciones higiénicas, se tomaron medidas a través de importantes desarrollos urbanos como la transformación de París bajo las órdenes del Barón Haussmann, el Prefecto del Departamento del Sena, entre 1853 y 1870. Según Napoleón III, Haussmann trazó el nuevo plan de París y empezó con el ‘Eventrement’ de los barrios insalubres de la ciudad abriendo grandes calles rectilíneas y longitudinales. De hecho, continuaba el trabajo ya propuesto por Napoleón I e iniciado más tarde por el conde de Rambuteau en 1839 bajo las mismas preocupaciones de higiene. Los objetivos de Haussmann eran embellecer y modernizar la ciudad y, sobre todo, mejorar las condiciones de vida y la salud pública y proporcionar a todos los ciudadanos luz, aire, agua, parques públicos y jardines. Por un lado, fue capaz de reunir un equipo distinguido como Alphand, Barillet-Deschamps, Davioud y Hittorff que crearon y construyeron los paseos y plazas de París. Sus diseños y elementos urbanos fueron estandarizados y sistematizados convirtiéndose en un modelo urbano e influenciando el diseño urbano de las ciudades. El hecho que llevó a Remesar a desarrollar el “paradigma Alphand-Davioud-Hittorff”, donde las réplicas de su estilo todavía predomina en la configuración del paisaje, los espacios y elementos de nuestro centro histórico. Por otra parte, Haussmann recibió duras críticas de los opositores políticos que resultaron en su despido. Debido al ‘eventrement’, fue criticado por destruir las partes antiguas de la ciudad causando una pérdida en

  1. Argon activation analysis, application to dating by the potassium-argon method; Analyse par activation de l'argon. Application a la datation par la methode potassium-argon

    Energy Technology Data Exchange (ETDEWEB)

    Dumesnil, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-07-01

    Activation analysis using radiogenic argon-40 has been applied to rock-dating by the K-Ar method. The argon is extracted from the sample, purified, activated to saturation in a flux of 2 X 10{sup 13} neutrons/cm{sup 2} sec{sup -1} and measured by gamma spectroscopy. The sensitivity obtained is such that it is possible to measure amounts of argon corresponding to age of a few thousand years only. However since it has not been possible to measure the amount of pollution of radiogenic argon by atmospheric argon with any accuracy, the measurable age limit is in fact of the order of MY. The method has been applied to basalts from the Mont-Dore region. The results obtained are in fairly good agreement with geological, stratigraphic and paleomagnetic data. (author) [French] L'analyse par activation de l'argon 40 radiogenique a ete appliquee a la datation des roches par la methode K-Ar. L'argon est extrait de l'echantillon, purifie, active a saturation dans un flux de 2.10{sup 13} neutrons.cm{sup -2}.s{sup -1} et mesure en spectrometrie gamma. La sensibilite obtenue est telle qu'il est possible de mesurer des quantites d'argon correspondant a des ages de quelques milliers d'annees seulement. Cependant la correction de pollution de l'argon radiogenique par l'argon atmospherique n'ayant pu etre etablie avec precision, la limite d'age mesurable pratique est de l'ordre de 1 Ma. La methode a ete appliquee aux basaltes de la region du Mont-Dore. Les ages obtenus sont en assez bon accord avec les donnees geologiques, stratigraphiques et paleomagnetiques. (auteur)

  2. 30 CFR 746.10 - Information collection.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Information collection. 746.10 Section 746.10... LANDS PROGRAM REVIEW AND APPROVAL OF MINING PLANS § 746.10 Information collection. The information... U.S.C. 3507 and assigned clearance number 1029-0026. The information is being collected to determine...

  3. Numerical analysis of resonances induced by s wave neutrons in transmission time-of-flight experiments with a computer IBM 7094 II; Methodes d'analyse des resonances induites par les neutrons s dans les experiences de transmission par temps de vol et automatisation de ces methodes sur ordinateur IBM 7094 II

    Energy Technology Data Exchange (ETDEWEB)

    Corge, Ch [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-01-01

    Numerical analysis of transmission resonances induced by s wave neutrons in time-of-flight experiments can be achieved in a fairly automatic way on an IBM 7094/II computer. The involved computations are carried out following a four step scheme: 1 - experimental raw data are processed to obtain the resonant transmissions, 2 - values of experimental quantities for each resonance are derived from the above transmissions, 3 - resonance parameters are determined using a least square method to solve the over determined system obtained by equalling theoretical functions to the correspondent experimental values. Four analysis methods are gathered in the same code, 4 - graphical control of the results is performed. (author) [French] L'automatisation, sur ordinateur IBM 7094/II, de l'analyse des resonances induites par les neutrons s dans les experiences de transmission par temps de vol a ete accomplie en la decomposant selon un schema articule en quatre phases: 1 - le traitement des donnees experimentales brutes pour obtenir les transmissions interfero-resonnantes, 2 - la determination des grandeurs d'analyse a partir des transmissions precedentes, 3 - l'analyse proprement dite des resonances dont les parametres sont obtenus par la resolution d'un systeme surabondant. Quatre methodes d'analyse sont groupees en un meme programme, 4 - la procedure de verification graphique. (auteur)

  4. Etk/Bmx regulates proteinase-activated-receptor1 (PAR1 in breast cancer invasion: signaling partners, hierarchy and physiological significance.

    Directory of Open Access Journals (Sweden)

    Irit Cohen

    Full Text Available BACKGROUND: While protease-activated-receptor 1 (PAR(1 plays a central role in tumor progression, little is known about the cell signaling involved. METHODOLOGY/PRINCIPAL FINDINGS: We show here the impact of PAR(1 cellular activities using both an orthotopic mouse mammary xenograft and a colorectal-liver metastasis model in vivo, with biochemical analyses in vitro. Large and highly vascularized tumors were generated by cells over-expressing wt hPar1, Y397Z hPar1, with persistent signaling, or Y381A hPar1 mutant constructs. In contrast, cells over-expressing the truncated form of hPar1, which lacks the cytoplasmic tail, developed small or no tumors, similar to cells expressing empty vector or control untreated cells. Antibody array membranes revealed essential hPar1 partners including Etk/Bmx and Shc. PAR(1 activation induces Etk/Bmx and Shc binding to the receptor C-tail to form a complex. Y/A mutations in the PAR(1 C-tail did not prevent Shc-PAR(1 association, but enhanced the number of liver metastases compared with the already increased metastases obtained with wt hPar1. We found that Etk/Bmx first binds via the PH domain to a region of seven residues, located between C378-S384 in PAR(1 C-tail, enabling subsequent Shc association. Importantly, expression of the hPar1-7A mutant form (substituted A, residues 378-384, which is incapable of binding Etk/Bmx, resulted in inhibition of invasion through Matrigel-coated membranes. Similarly, knocking down Etk/Bmx inhibited PAR(1-induced MDA-MB-435 cell migration. In addition, intact spheroid morphogenesis of MCF10A cells is markedly disrupted by the ectopic expression of wt hPar1. In contrast, the forced expression of the hPar1-7A mutant results in normal ball-shaped spheroids. Thus, by preventing binding of Etk/Bmx to PAR(1 -C-tail, hPar1 oncogenic properties are abrogated. CONCLUSIONS/SIGNIFICANCE: This is the first demonstration that a cytoplasmic portion of the PAR(1 C-tail functions as a scaffold

  5. Parálisis del músculo oblicuo superior atípica

    Directory of Open Access Journals (Sweden)

    Pedro Daniel Castro Pérez

    Full Text Available Las paresias y parálisis oculomotoras implican todos aquellos procesos susceptibles de producir un déficit parcial o total de los movimientos del globo ocular. La lesión puede estar en cualquier parte del sistema oculomotor que incluye la corteza cerebral, el tronco cerebral, nervios, placa neuromuscular y del propio músculo. Las paresias y/o parálisis del músculo oblicuo superior o IV par craneal constituye una de las más frecuentes en la práctica médica estrabológica, puede ser de etiología congénita o adquirida, se caracteriza por hipertropía que aumenta con la inclinación de la cabeza hacia el hombro del lado del ojo afectado (signo de Bielschowsky, anisotropía en V, exciclotropía. Los pacientes con paresias y/o parálisis adquirida muestran diplopía vertical y torsional que aumenta con la mirada hacia abajo, tortícolis con inclinación de la cabeza hacia el lado opuesto del ojo afectado y descenso del mentón. El paciente acude a consulta por presentar diplopía vertical y torsional de 13 años de evolución. Al examen de la motilidad ocular había ortotropía en la Posición Primaria de la Mirada con hiperforia al cover test ojo izquierdo, 10 Dp base inferior por barra de prismas, exciclotropía 5*, tortícolis hacia la derecha y Bielschowsky positivo hacia el lado izquierdo. La impresión diagnóstica fue paresia adquirida del músculo OS izquierdo de etiología no precisada. El tratamiento realizado fue la retroinserción del recto superior del ojo izquierdo 4 mm más el desplazamiento temporal de un 1/4 de la inserción con el objetivo de eliminar la diplopía vertical y torsional y la posición anómala de la cabeza.

  6. Par Pond vegetation status 1996

    International Nuclear Information System (INIS)

    Mackey, H.E. Jr.; Riley, R.S.

    1996-12-01

    The water level of Par Pond was lowered approximately 20 feet in mid-1991 in order to protect downstream residents from possible dam failure suggested by subsidence on the downstream slope of the dam and to repair the dam. This lowering exposed both emergent and nonemergent macrophyte beds to drying conditions resulting in extensive losses. A survey of the newly emergent, shoreline aquatic plant communities of Par Pond began in June 1995, three months after the refilling of Par Pond to approximately 200 feet above mean sea level. These surveys continued in July, September, and late October, 1995, and into the early spring and late summer of 1996. Communities similar to the pre-drawdown, Par Pond aquatic plant communities continue to become re-established. Emergent beds of maidencane, lotus, waterlily, watershield, and Pontederia are extensive and well developed. Measures of percent cover, width of beds, and estimates of area of coverage with satellite data indicate regrowth within two years of from 40 to 60% of levels prior to the draw down. Cattail occurrence continued to increase during the summer of 1996, especially in the former warm arm of Par Pond, but large beds common to Par Pond prior to the draw down still have not formed. Lotus has invaded and occupies many of the areas formerly dominated by cattail beds. To track the continued development of macrophytes in Par Pond, future surveys through the summer and early fall of 1997, along with the evaluation of satellite data to map the extent of the macrophyte beds of Par Pond, are planned

  7. Determinación de parámetros físicos aplicables en el escalamiento de la síntesis de zeolita NaA, a partir de geles aluminosilicatos

    OpenAIRE

    Carmen M. López; Adriana García; Miguel Ríos; Neyla Rondón; Luis García; Johliny Casanova; Kevin Contreras

    2016-01-01

    Se estudió el efecto de parámetros físicos que influyen en la preparación de la zeolita NaA, a fin de determinar condiciones favorables para realizar el escalamiento de esta síntesis. Partiendo de una mezcla de síntesis con composición fija y cristalización a 80 °C se estudiaron los siguientes parámetros: orden y velocidad de agregado de las soluciones de partida, velocidad y tiempo de agitación de la mezcla de síntesis, agitación durante la cristalización, tiempo de cristalización y reciclo ...

  8. 39 CFR 10.2 - Advisory service.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Advisory service. 10.2 Section 10.2 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE RULES OF CONDUCT FOR POSTAL SERVICE GOVERNORS (ARTICLE X) § 10.2 Advisory service. (a) The General Counsel is the Ethical...

  9. Measurement of D{sub s}{sup +} and D{sub s}{sup *+} Production in B Meson Decays and from Continuum e{sup +}e{sup -} Annihilations at {radical}s=10.6 GeV.

    Energy Technology Data Exchange (ETDEWEB)

    Ganzhur, Sergey

    2001-07-30

    New precise measurements of D{sub s}{sup +} and D*{sub s}{sup +} meson production from B mesons and q{bar q} continuum events near the {Upsilon}(4S) resonance are presented in this paper. Using the BABAR data recorded in 1999 and 2000 of 20.8 fb{sup -1} on-resonance and 2.6 fb{sup -1} off-resonance, we measure the inclusive branching fractions (B {yields} D{sub s}{sup +}) = (10.93 {+-} 0.19 {+-} 0.58 {+-} 2.73)% and (B {yields} D*{sub s}{sup +}) = (7.94 {+-} 0.82 {+-} 0.72 {+-} 1.99)%, where the first error is statistical, the second is the systematic error, and the third is the error due to the D{sub s}{sup +} {yields} {pi}{sup +} branching fraction uncertainty. The branching fractions (B {yields} D{sup (*)}{sub s}{sup +} {bar D}(*)) = (5.07 {+-} 0.09 {+-} 0.34 {+-} 1.27)% and (B {yields} D*{sub s}{sup +} {bar D}(*)) = (4.07 {+-} 0.42 {+-} 0.53 {+-} 1.02)% have been determined from the measured D{sup (*)}{sub s}{sup +} momentum spectra.

  10. Chemical, physical, profile and laboratory analysis oceanographic data collected aboard the Brooks McCall in the Gulf of Mexico from 2010-07-10 to 2010-07-14 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0069052)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, physical, profile and laboratory analysis oceanographic data were collected aboard the Brooks McCall in the Gulf of Mexico from 2010-07-10 to 2010-07-14 in...

  11. Construyendo infraestructuras para la movilidad: 
el caso del sistema de bicicletas en libre servicio de París

    Directory of Open Access Journals (Sweden)

    Martín Tironi

    2011-03-01

    Full Text Available Ciudad sustentable, nuevas tecnologías, movilidad. Estas, entre otras, son las referencias que se suelen utilizar para designar el fenómeno de globalización de los sistemas de bicicletas en libre servicio (BLS Valorados por su carácter amigable con el planeta, estos sistemas son hoy un must para las ciudades que desean inscribirse en la llamada “cultura verde”. Tomando como referencia el programa Vélib’ (París, me propongo problematizar nociones como ‘ciudad sustentable’ y ‘movilidad’, y describir el trabajo colectivo y siempre controversial necesario para elaborar y estabilizar una infraestructura como la de dicho programa. Busco describir los instrumentos, estrategias y desplazamientos (políticos, urbanos y técnicos utilizados para la concepción del sistema de usuarios de BLS más extenso del mundo. En la primera parte del texto, de carácter ensayístico, describo cómo para cierta literatura el fenómeno de las bicicletas públicas es signo del renacer de las prácticas urbanas en las grandes metrópolis. A continuación, y con base en material empírico proveniente del estudio de caso del sistema BLS de París, analizo dos controversias que permiten situar, desde un enfoque pragmático, el estudio de estas infraestructuras de movilidad.

  12. Eficiência de isolamento e de plaqueamento de protoplastos de laranja-doce

    Directory of Open Access Journals (Sweden)

    Lívia Mendes de Castro

    2011-06-01

    Full Text Available O isolamento e plaqueamento de protoplastos são fatores fundamentais para o sucesso no cultivo in vitro deste tipo de explante visando a manipulações genéticas. A composição da solução enzimática no isolamento, a densidade de cultivo, bem como o próprio genótipo utilizado são variáveis importantes nestas etapas. Desta forma, o objetivo do trabalho foi avaliar a eficiência de isolamento de protoplastos em função de três soluções enzimáticas e a eficiência de plaqueamento em função de cinco densidades de protoplastos e diferentes composições de meio de cultura em cultivares de laranja-doce. As soluções enzimáticas avaliadas para o isolamento de protoplastos foram: 1. celulase Onozuka RS 1%, macerase R-10 1% e pectoliase 0,2%; 2. celulase Onozuka RS 1%, macerase R-10 1% ; 3. celulase Onozuka R-10 4%, macerase R-10 1%. O plaqueamento dos protoplastos foi realizado nas densidades de 2 x 10(4; 5 x 10(4; 10(5; 2x 10(5 e 3 x 10(5 protoplastos.mL-1, nos meios de cultura EME 0,7M, BH3 0,7M e BH3 + EME 0,7M em ausência de luz, a 25 ± 1 ºC. A solução enzimática 2 proporcionou maior rendimento no isolamento de protoplastos das cultivares 'Hamlin', 'Natal' e 'Pera', e a solução enzimática 1 foi a mais adequada para a laranja 'Westin'. Para a cultivar 'Lima-Verde', a solução enzimática 3 foi a mais eficiente. A eficiência final de plaqueamento, avaliada aos 90 dias de cultivo, foi superior nas densidades de 3 x 10(5 e 2 x 10(5 protoplastos.mL-1 para as cultivares 'Hamlin', 'Natal' e 'Lima-Verde', e nas densidades de 2 x 10(5 e 10(5 protoplastos.mL-1 para a laranja 'Westin'.

  13. Possibilités de franchissement du seuil de Beaucaire par les aloses du Rhône

    Directory of Open Access Journals (Sweden)

    LARINIER M.

    1978-01-01

    Full Text Available Douze barrages ont été construits depuis 1947 sur le Rhône à l'aval de LYON. Aucun des dispositifs de franchissement prévus pour les poissons migrateurs ne donne satisfaction, en particulier en ce qui concerne la remontée des aloses (Alosa alosa et Alosa fallax nilotica. De nombreuses observations réalisées sur le seuil de Beaucaire ont permis de déterminer la vitesse de nage et le comportement des aloses dans l'échelle à ralentisseurs de type LACHADENEDE installée sur cet ouvrage. Aucune alose ne s'engage dans la passe quand la vitesse moyenne y excède 1,5 m/s. L'inefficacité de ce dispositif de franchissement s'explique par son manque d'attractivité et ses caractéristiques hydrauliques inadéquates, compte tenu des faibles capacités de nage des aloses.

  14. Vyhodnocení výškových změn v poklesové kotlině u Karviné

    Czech Academy of Sciences Publication Activity Database

    Doležalová, Hana; Kajzar, Vlastimil; Souček, Kamil; Staš, Lubomír

    2008-01-01

    Roč. 8, č. 2 (2008), s. 21-27 ISSN 1213-1962. [OVA ´08 /17./ - Nové poznatky a měření v seizmologii, inženýrské geofyzice a geotechnice. Ostrava, 08.04.2008-10.04.2008] R&D Projects: GA ČR GA105/07/1586; GA ČR GA105/07/0878 Institutional research plan: CEZ:AV0Z30860518 Keywords : GPS * subsidence depression * undermining Subject RIV: DH - Mining, incl. Coal Mining

  15. 48 CFR 228.105 - Other types of bonds.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Other types of bonds. 228..., DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds 228.105 Other types of bonds... surety company are desired. [70 FR 8538, Feb. 22, 2005] ...

  16. Evaluation of vertical and horizontal movements in the subsidence depression near Karviná

    Czech Academy of Sciences Publication Activity Database

    Doležalová, Hana; Kajzar, Vlastimil; Souček, Kamil; Staš, Lubomír

    2010-01-01

    Roč. 7, č. 3 (2010), s. 355-361 ISSN 1214-9705. [Czech-Polish Workshop on recent geodynamics of the Sudety Mts. and adjacent areas /10./. Sklarska Poreba, 05.11.2009-07.11.2009] R&D Projects: GA ČR GA105/07/1586; GA ČR GA105/07/0878 Institutional research plan: CEZ:AV0Z30860518 Keywords : subsidence depression * GPS * horizontal shifts Subject RIV: DH - Mining, incl. Coal Mining Impact factor: 0.452, year: 2010 http://www.irsm.cas.cz/?Lang=CZE&Menu=25,29,0,0;&File=Obsah/AGG/Contents/AGGC7_3%28159%2910.htm

  17. Vegetação da área de proteção ambiental Jabotitiua-Jatium. Município de Viseu, Pará, Brasil Vegetation of the Jabotitiua-Jatium Protected Environmental Area, municipality of Viseu, Pará, Brazil

    Directory of Open Access Journals (Sweden)

    João Ubiratan M. dos Santos

    2003-01-01

    Full Text Available A Área de Proteção Ambiental Jabotitiua-Jatium, localiza-se no município de Viseu, Nordeste do Pará, ocupando uma área de 14.25 ha, sendo criada através da lei municipal n.º 002/98, de 07 de abril de 1998, visando a proteção de um trecho representativo e preservado do litoral paraense, abrigando um espetacular ninhal de guarás (Eudocimus ruber L., ave costeira que encontra-se na lista oficial da fauna em extinção no Brasil. Objetivando auxiliar o plano de manejo ambiental desta APA, o estudo em questão identificou quatro tipos de ambientes, classificados em Mangue, Campo Natural, Floresta Mista com Palmeiras e Restinga. Utilizando-se a metodologia da Avaliação Ecológica Rápida (AER, foi identificado um total de 141 espécies, representantes de 61 famílias. O maior número de espécies corresponde à Floresta Mista com Palmeiras, apresentando 66 representantes, e a menor representatividade diz respeito ao mangue, com apenas quatro espécies. Fabaceae (15, Cyperaceae (10 e Rubiaceae (10, destacaram-se em número de espécies, correspondendo, juntas, a 24,82% do total das espécies registradas. As ervas representam a maioria (48 quanto a forma de vida, seguida dos arbustos (38, árvores (34, Lianas (13, estipe (5 e epífitos (3.The Jabotitiua-Jatium Protected Area comprises 14.25 ha in the Municipal District of Viseu in northeast Pará. The area was established by municipal law 002/98 on 7 April 1998 in order to protect a representative sample of coastal Amazonia, including an important nesting site of the endangered scarlet ibis (Eudocimus ruber L.. The objective of this study was to provide floristic information useful for developing a management plan for the area. Four habitat types were found to occur in the area: mangrove, savanna?, mixed palm-forest, and sandy coastal. A Rapid Ecological Assessment (AER of the area identified 141 species of angiosperms in 61 families. The mixed palm-forest, with 66 species, is the most

  18. Tuberculose lymphonodale cervicale chez les enfants vaccines par ...

    African Journals Online (AJOL)

    La tuberculose ganglionnaire cervicale est une localisation extrapulmonaire relativement fréquente chez l'enfant. Elle pose essentiellement des difficultés de prévention. L'objectif de ce travail est d'étudier les particularités diagnostiques et thérapeutiques chez des enfants vaccinés par le BCG. Matériel et méthodes: Nôtre ...

  19. Radioactive Air Emissions Notice of Construction for the 105-KW Basin integrated water treatment system filter vessel sparging vent

    Energy Technology Data Exchange (ETDEWEB)

    Kamberg, L.D.

    1998-02-23

    This document serves as a notice of construction (NOC), pursuant to the requirements of Washington Administrative Code (WAC) 246-247-060, and as a request for approval to construct, pursuant to 40 Code of Federal Regulations (CFR) 61.07, for the Integrated Water Treatment System (IWTS) Filter Vessel Sparging Vent at 105-KW Basin. Additionally, the following description, and references are provided as the notices of startup, pursuant to 40 CFR 61.09(a)(1) and (2) in accordance with Title 40 Code of Federal Regulations, Part 61, National Emission Standards for Hazardous Air Pollutants. The 105-K West Reactor and its associated spent nuclear fuel (SNF) storage basin were constructed in the early 1950s and are located on the Hanford Site in the 100-K Area about 1,400 feet from the Columbia River. The 105-KW Basin contains 964 Metric Tons of SNF stored under water in approximately 3,800 closed canisters. This SNF has been stored for varying periods of time ranging from 8 to 17 years. The 105-KW Basin is constructed of concrete with an epoxy coating and contains approximately 1.3 million gallons of water with an asphaltic membrane beneath the pool. The IWTS, which has been described in the Radioactive Air Emissions NOC for Fuel Removal for 105-KW Basin (DOE/RL-97-28 and page changes per US Department of Energy, Richland Operations Office letter 97-EAP-814) will be used to remove radionuclides from the basin water during fuel removal operations. The purpose of the modification described herein is to provide operational flexibility for the IWTS at the 105-KW basin. The proposed modification is scheduled to begin in calendar year 1998.

  20. Lambeaux autofermants pour le traitement des brulures electriques du scalp par haut voltage

    Science.gov (United States)

    Hafidi, J.; El Mazouz, S.; El Mejatti, H.; Fejjal, N.; Gharib, N.E.; Abbassi, A.; Belmahi, A.M.

    2011-01-01

    Summary Les brûlures électriques par haut voltage sont responsables de gros dégâts tissulaires en immédiat et dans les jours suivant l’accident du fait de la chaleur importante dégagée par effet joule et de la thrombose microvasculaire évolutive. Les pertes de substances du scalp secondaires à ces brûlures nécessitent une couverture par lambeaux vu la destruction du périoste et du calvarium en regard. De juin 1997 à juin 2008, 15 patients ont été traités pour des pertes de substance du scalp secondaires à des brûlures électriques par haut voltage de diamètre allant de 8 à 11 cm et siégeant dans la région tonsurale. Ces patients ont été opérés dans la première semaine suivant l’accident. Les pertes de substance du scalp de taille moyenne secondaires à ces brûlures peuvent être couvertes per primam de façon fiable par des lambeaux locaux axialisés et multiples. Nous relatons l’expérience du Service de Chirurgie Plastique du Centre Hospitalier Universitaire Ibn-Sina, Rabat, Maroc, dans la gestion et la prise en charge de ces brûlures. PMID:22262963

  1. 48 CFR 32.105 - Uses of contract financing.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Uses of contract financing... CONTRACTING REQUIREMENTS CONTRACT FINANCING Non-Commercial Item Purchase Financing 32.105 Uses of contract financing. (a) Contract financing methods covered in this part are intended to be self-liquidating through...

  2. 48 CFR 728.105-1 - Advance payment bonds.

    Science.gov (United States)

    2010-10-01

    ... GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds 728.105-1 Advance payment bonds. (a) Generally, advance payment bonds will not be required in connection with USAID contracts containing an advance... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Advance payment bonds. 728...

  3. Experimental study of a diod with magnetic insulation at the pulse duration more or equal to 10-5 s

    International Nuclear Information System (INIS)

    Rojfe, I.M.; Burtsev, V.A.; Vasilevskij, M.A.; Ehngel'ko, V.I.

    1980-01-01

    Results of the experimental investigation of a heavy-current diod with magnetic insulation are presented. Diod characteristics dependence on magnetic field distribution and magnitude in the accelerating interval has been studied. It is noted that the magnetic insulation of the accelerating tube has permitted to obtain the pulse duration of > or approximately 10 sub(s)sup(-5) at the voltage of > or approximately 400 kV in the tube and electron beam current of 3-4 kA. Maximum insulating magnetic field is 2.5 kOe. It is shown that the pulse duration of electron current in diods with magnetic insulation is limitted by break-down development along the accelerating tube surface. When magnetic field on the cathode is approximately 5kOe thre is a time interval of 4-5μs when the impedance is constant. The difference of diod impedance behaviour in time in these two cases are defined by a distinct expansion of cathode plasma at low magnetic fields. Cathode lateral surface plays a significant role in the process of plasma expantion. When the interelectrode gap is 3-5 cm and the voltage amplitude - < or approximately 400 kV it is possible to obtain tubular electron beams with the pulse duration of 10-15 μs, beam energy of 5-6 kJat a relatively small (approximately equal to 5kOe) magnitudes of magnetic field on the cathode. A possibility is shown to use multipoint graphite cathodes with a large area for obtaining tubular beams. The tubular electron beam of approximately equal to 400 A with the pulse duration of 25 μs have been obtained in the first experiments with such cathode at the voltage amplitude of < or approximately 150 kV. The conclusion is made that the tube magnetic isolation permits to increase considerably the pulse duration

  4. Positron emission tomography imaging of CD105 expression with {sup 89}Zr-Df-TRC105

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Hao; Yang, Yunan [University of Wisconsin - Madison, Department of Radiology, Madison, WI (United States); Severin, Gregory W.; Engle, Jonathan W.; Zhang, Yin; Barnhart, Todd E.; Nickles, Robert J. [University of Wisconsin - Madison, Department of Medical Physics, Madison, WI (United States); Liu, Glenn [University of Wisconsin - Madison, Department of Medicine, Madison, WI (United States); University of Wisconsin Carbone Cancer Center, Madison, WI (United States); Leigh, Bryan R. [TRACON Pharmaceuticals, Inc, San Diego, CA (United States); Cai, Weibo [University of Wisconsin - Madison, Department of Radiology, Madison, WI (United States); University of Wisconsin - Madison, Department of Medical Physics, Madison, WI (United States); University of Wisconsin Carbone Cancer Center, Madison, WI (United States)

    2012-01-15

    High tumor microvessel density correlates with a poor prognosis in multiple solid tumor types. The clinical gold standard for assessing microvessel density is CD105 immunohistochemistry on paraffin-embedded tumor specimens. The goal of this study was to develop an {sup 89}Zr-based PET tracer for noninvasive imaging of CD105 expression. TRC105, a chimeric anti-CD105 monoclonal antibody, was conjugated to p-isothiocyanatobenzyl-desferrioxamine (Df-Bz-NCS) and labeled with {sup 89}Zr. FACS analysis and microscopy studies were performed to compare the CD105 binding affinity of TRC105 and Df-TRC105. PET imaging, biodistribution, blocking, and ex-vivo histology studies were performed on 4T1 murine breast tumor-bearing mice to evaluate the pharmacokinetics and tumor-targeting of {sup 89}Zr-Df-TRC105. Another chimeric antibody, cetuximab, was used as an isotype-matched control. FACS analysis of HUVECs revealed no difference in CD105 binding affinity between TRC105 and Df-TRC105, which was further validated by fluorescence microscopy. {sup 89}Zr labeling was achieved with high yield and specific activity. Serial PET imaging revealed that the 4T1 tumor uptake of {sup 89}Zr-Df-TRC105 was 6.1 {+-} 1.2, 14.3 {+-} 1.2, 12.4 {+-} 1.5, 7.1 {+-} 0.9, and 5.2 {+-} 0.3 %ID/g at 5, 24, 48, 72, and 96 h after injection, respectively (n = 4), higher than all organs starting from 24 h after injection, which provided excellent tumor contrast. Biodistribution data as measured by gamma counting were consistent with the PET findings. Blocking experiments, control studies with {sup 89}Zr-Df-cetuximab, and ex-vivo histology all confirmed the in vivo target specificity of {sup 89}Zr-Df-TRC105. We report here the first successful PET imaging of CD105 expression with {sup 89}Zr as the radiolabel. Rapid, persistent, CD105-specific uptake of {sup 89}Zr-Df-TRC105 in the 4T1 tumor was observed. (orig.)

  5. Numerical analysis of resonances induced by s wave neutrons in transmission time-of-flight experiments with a computer IBM 7094 II; Methodes d'analyse des resonances induites par les neutrons s dans les experiences de transmission par temps de vol et automatisation de ces methodes sur ordinateur IBM 7094 II

    Energy Technology Data Exchange (ETDEWEB)

    Corge, Ch. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-01-01

    Numerical analysis of transmission resonances induced by s wave neutrons in time-of-flight experiments can be achieved in a fairly automatic way on an IBM 7094/II computer. The involved computations are carried out following a four step scheme: 1 - experimental raw data are processed to obtain the resonant transmissions, 2 - values of experimental quantities for each resonance are derived from the above transmissions, 3 - resonance parameters are determined using a least square method to solve the over determined system obtained by equalling theoretical functions to the correspondent experimental values. Four analysis methods are gathered in the same code, 4 - graphical control of the results is performed. (author) [French] L'automatisation, sur ordinateur IBM 7094/II, de l'analyse des resonances induites par les neutrons s dans les experiences de transmission par temps de vol a ete accomplie en la decomposant selon un schema articule en quatre phases: 1 - le traitement des donnees experimentales brutes pour obtenir les transmissions interfero-resonnantes, 2 - la determination des grandeurs d'analyse a partir des transmissions precedentes, 3 - l'analyse proprement dite des resonances dont les parametres sont obtenus par la resolution d'un systeme surabondant. Quatre methodes d'analyse sont groupees en un meme programme, 4 - la procedure de verification graphique. (auteur)

  6. Enquete sur les aspects toxicologiques de la phytotherapie utilisee par un herboriste à Fes, Maroc

    Science.gov (United States)

    Zeggwagh, Ali Amine; Lahlou, Younes; Bousliman, Yassir

    2013-01-01

    Introduction Dans le but d'étudier l'aspect toxicologique des plantes médicinales utilisées en médecine traditionnelle, une étude ethnobotanique a été réalisée à la ville de Fès au centre du Maroc. Méthodes Ont été inclus dans l'étude tous les patients ayant bénéficié d'une prescription par l'herboriste de plantes à visée thérapeutique. La discussion de nos résultats s'est faite sur la base d'une revue de la littérature avec identification des principales plantes toxiques utilisées en phytothérapie au Maroc. L'approche bibliographique a permis de compléter les informations. Résultats L'âge moyen des patients traités par des plantes (38 femmes, 32 hommes) était de 35 ± 18 ans. L'enquête ethnobotanique à révélé que la majorité des plantes médicinales étaient utilisées contre les affections urinaires (21%), suivi des maladies de l'appareil digestif (19.6%) et des maladies rhumatologiques (18.2%). Le nombre de plantes prescrits par l'herboriste a été de 53 dont 5 sont potentiellement toxiques. L'identification taxonomique des plantes prescrites a recensé 30 familles dont les plus représentées sont les Lamiaceae (23.33%), les Apiaceae (13,33%) et les Asteraceae (10%). La prescription des plantes considérées comme toxiques a concerné 7,1% des consultants traités par les plantes médicinales. Aucune complication inhérente aux plantes prescrites n'a été déplorée. Conclusion Malgré les résultats encourageants de notre enquête sur le compte de la phytothérapie, la pratique de la phytothérapie est laissée à la vulgarisation et à l'oubli scientifique, législatif et universitaire. PMID:23734270

  7. El Acuerdo de París: ¿Una nueva idea sobre la arquitectura climática internacional?

    OpenAIRE

    Bueno Rubial, María del Pilar

    2016-01-01

    Este artículo propone un debate desde enfoques teóricos de las Relaciones Internacionales acerca de la arquitectura climática internacional. Para ello se vale de los aportes del constructivismo, especialmente en la mirada de Alexander Wendt, analizando el proceso de construcción del Acuerdo de París como nueva idea. La arquitectura climática internacional pergeñada en Río de Janeiro y profundizada en Kioto estuvo signada por cuatro lógicas que reproducían las condiciones del Si...

  8. 45 CFR 2544.105 - What is the legal authority for soliciting and accepting donations to the Corporation?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false What is the legal authority for soliciting and accepting donations to the Corporation? 2544.105 Section 2544.105 Public Welfare Regulations Relating to... DONATIONS § 2544.105 What is the legal authority for soliciting and accepting donations to the Corporation...

  9. Thermodynamic functions of element 105 in neutral and ionized states

    International Nuclear Information System (INIS)

    Pershina, V.; Fricke, B.; Ionova, G.V.; Johnson, E.

    1994-01-01

    The basic thermodynamic functions, the entropy, free energy, and enthalpy, for element 105 (hahnium) in electronic configurations d 3 s 2 , d 3 sp, and d 4 s 1 and for its + 5 ionized state (5f 14 ) have been calculated as a function of temperature. The data are based on the results of the calculations of the corresponding electronic states of element 105 using the multiconfiguration Dirac-Fock method. 19 refs., 1 fig., 11 tabs

  10. Otimização da extração enzimática da proteína do feijão - doi: 10.4025/actascitechnol.v32i3.6277

    Directory of Open Access Journals (Sweden)

    Carlos de Oliveira Lopes Junior

    2010-11-01

    Full Text Available Considerando-se a importância do feijão na dieta do brasileiro e, ainda, que este alimento não é permitido na alimentação de fenilcetonúricos, é fundamental promover a extração de suas proteínas, visando à posterior remoção de fenilalanina. No intuito de se otimizar a extração proteica do feijão, dois métodos enzimáticos foram, inicialmente, empregados. Para aquele que produziu o maior rendimento de extração proteica (REP, foi realizado um estudo do efeito de diversos parâmetros, tais como velocidade de centrifugação, tempo de reação, pH inicial e tipo de enzima (uma de Bacillus licheniformis, duas de Bacillus subtilis, uma de Aspergillus sojae e uma de Papaya carica. Os resultados indicaram que o melhor método foi o que empregou uma concentração de matéria-prima de 1:10 (p v-1, pH inicial de 10,5, temperatura de 50°C, e ausência de agitação em ultraturrax. Com relação aos parâmetros testados, o maior REP (93,1% foi obtido ao se utilizar a enzima de Bacillus licheniformis, na velocidade de centrifugação de 10.640 x g, tempo de reação de 3h e pH inicial de 10,5.

  11. Accouchement par césarienne et mortalité maternelle du postpartum

    OpenAIRE

    Deneux-Tharaux , Catherine; Carmona , Elodie; Bouvier-Colle , Marie-Hélène; Bréart , Gérard

    2006-01-01

    Objectifs Une augmentation continue du taux d'accouchements par césarienne (CS)est observée dans la plupart des pays depuis 20 ans. Cette évolution a suscité l'émergence d'un débat controversé sur les risques et les bénéfices associés à la CS. L'objectif de cette étude était d'estimer le risque de mort maternelle du postpartum lié directement à la CS par comparaison à l'accouchement par voie basse, globalement et en distinguant les CS pre- ou intra- partum . Méthode Etude cas/témoins. Les cas...

  12. WATER TEMPERATURE, SALINITY, and others collected from NEW HORIZON in Gulf of California and NE Pacific (limit-180) from 2008-07-10 to 2008-08-06 (NCEI Accession 0131141)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Basic hydrographic properties (T, S, P, calculated density, chlorophyll A fluorescence, surface and in situ spherical PAR, and dissolved O2) collected via CTD...

  13. 39 CFR 10.3 - Post-employment activities.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Post-employment activities. 10.3 Section 10.3 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF GOVERNORS OF THE U.S. POSTAL SERVICE RULES OF CONDUCT FOR POSTAL SERVICE GOVERNORS (ARTICLE X) § 10.3 Post-employment activities. Governors are subject...

  14. La prise en charge des suicides par précipitation en traumatologie

    Directory of Open Access Journals (Sweden)

    Abdelmajid Elmrini

    2010-09-01

    Full Text Available OBJECTIFS: A travers ce travail, l’épidémiologie et la psychopathologie du suicide par précipitation seront rappelées, le rôle du chirurgien traumatologue dans la restauration physique et psychique sera démontré. METHODES: Nous rapportons une étude rétrospective de 15 suicidants par précipitation admis pour des traumatismes complexes de l’appareil locomoteur entre 2004 et 2007. RESULTATS: Il s’agissait de primosuicidants, comprenant 10 femmes et 5 hommes. L’âge moyen des hommes est de 26,5 ans (24-34 ans et celui des femmes de 40,7 ans (17-45 ans. Le bilan lésionnel des suicidants a retrouvé 14 fractures des membres inférieurs, 4 traumatisme du rachis avec compression médullaire dans 1 cas, une fracture du bassin; deux traumatismes du membre supérieur. Aucun de ces patients n’a présenté de lésions viscérales ni de traumatismes crâniofacial. 80% (n = 12 des patients souffraient d’une affection psychiatrique avant leur passage à l’acte suicidaire : 8 pour une pathologie dépressive et 4 pour une schizophrénie. Chaque suicidant a subi au moins un acte chirurgical. Tous les patients avaient poursuivi la prise en charge psychiatrique en ambulatoire. Nos résultats fonctionnels étaient satisfaisants sans complications. Aucun des patients n’a récidivé. La pathologie suicidaire représente un problème de santé publique. Le suicide par précipitation représente 5 % de l’ensemble des modalités suicidaires. Les traumatismes occasionnés par ce mode suicidaire sont complexes et graves. Leur prise en charge nécessite une collaboration multidisciplinaire. CONCLUSION: La réparation chirurgicale permet à la fois le rétablissement de la fonction et l’amélioration psychique du sujet prévenant contre une rechute dépressive ou une récidive suicidaire.

  15. Florística e estrutura do estrato arbóreo de uma floresta de várzea no município de Santa Bárbara do Pará, Estado do Pará, Brasil Floristic and structure of tree communities in the floodplain forest on municipallity of Santa Bárbara do Pará, State of Pará, Brazil

    Directory of Open Access Journals (Sweden)

    Gideão Costa dos Santos

    2006-12-01

    Full Text Available Este estudo teve como objetivo conhecer a composição florística e a estrutura do estrato arbóreo de uma floresta de várzea na localidade de São José do Aracy, no município de Santa Bárbara do Pará, estado do Pará, Brasil. Foram instaladas quatro parcelas de 100 x 100 m subdivididas em cinco transectos de 20 x 100 m e foram amostradas as espécies arbóreas lenhosas e palmeiras. Para as espécies lenhosas adotou-se diâmetro à altura do peito (DAP ³ 10cm e para palmeiras a circunferência à altura do peito (CAP ³ 10cm e estimou-se a altura. O material botânico coletado foi identificado em nível de família, gênero e espécie, sendo incorporado ao herbário João Murça Pires do Museu Paraense Emílio Goeldi (MPEG. Na análise fitossociológica foram calculados os parâmetros de Densidade Relativa (DR%, Freqüência Relativa (FR%, Dominância Relativa (DOMR%, Índice de Valor de Importância (IVI, Índice de Valor de Cobertura (IVC, Índice de similaridade de Sorenson (S', Índice de diversidade de Shannon (H' e Equabilidade (E'. Os resultados mostraram 29 famílias, 58 gêneros e 70 espécies. As famílias com maior diversidade foram Caesalpiniaceae, Mimosaceae e Papilionaceae, com nove, oito e sete espécies, respectivamente; Arecaceae e Papilionaceae obtiveram maior densidade (27,75% e 25,84%; treze famílias foram mais freqüentes com 4,88% entre elas; Papilionaceae com maior dominância e índice de valor de importância (37,50% e 68,21; Euterpe oleracea Mart. apresentou maior densidade relativa e Pterocarpus officinalis Jacq., maior dominância relativa, maior índice de valor de importância e de cobertura. O índice de diversidade de 2,63 foi considerado baixo, com equabilidade de 0,63 e similaridade de 0,60. A várzea estudada apresentou baixa diversidade em espécies.This research has taken place in four of 100 x 100 m in São José do Aracy, in the municipallity of Santa Bárbara do Pará, State of Pará, Brazil. Each

  16. Facteurs de risque de l'infection par le VIH dans le district de santé de Meyomessala au Cameroun

    Science.gov (United States)

    Mbopi-Keou, Francois-Xavier; Nguefack-Tsague, Georges; Kalla, Ginette Claude Mireille; Abessolo, Stéphanie Abo'o; Angwafo, Fru; Muna, Walinjom

    2014-01-01

    Introduction L'objectif de ce travail était de déterminer les facteurs de risque de l'infection par le VIH dans le district de santé de Meyomessala (Région du Sud) au Cameroun. Méthodes Il s'agissait d'une étude transversale, descriptive et analytique qui s'est déroulée de Février à Mai 2011. Pour cette étude, nous avons obtenu une clairance éthique. Résultats L’échantillon était constitué de 315 participants dont 181 (57,46%) hommes et 134 (42,54%) femmes. L’âge moyen était de 24,5±8ans (extrême: 15-45ans). Quarante personnes (40) étaient séropositifs, soit une prévalence de l'infection par le VIH de 12,7%. Cette prévalence augmentait significativement (p = 0) avec le nombre de partenaires occasionnels au cours des douze derniers mois, allant de 2,7% chez ceux n'ayant eu aucun partenaire occasionnel à 21,25% chez ceux ayant plus de trois partenaires occasionnels (RC = 9,72; IC = 1,27-74,14; P = 0,03). le fait d’être âgé entre 20 et 24 ans (RC = 4,88; IC = 1,74-13,67; p = 0), avoir plus de trois partenaires sexuels au cours des douze derniers mois (RC = 9,72; IC = 1,27-74,14; p = 0,03), avoir les rapports sexuels avec les prostitués (RC = 2,86; IC = 1,42-5,76; p = 0), avoir eu le chlamydia (RC = 3,00; IC = 1,07-8,39; p = 0,04), avoir eu la syphilis (RC = 3,35; IC = 1,57-7,14; p = 0), avoir des avantages sociaux lors du premier rapport sexuel (RC = 2,57; IC = 1,03-6,43; p = 0,04) constituaient des potentiels facteurs de risque du VIH. Conclusion Il apparait urgent d'intensifier les campagnes de sensibilisation au risque d'infection par le VIH et les maladies sexuellement transmissibles dans le district de santé de Meyomessala PMID:25419299

  17. Traitement De La Peripneumonie Contagieuse Bovine Par L ...

    African Journals Online (AJOL)

    Traitement De La Peripneumonie Contagieuse Bovine Par L'oxyteTracycline Longe Action Et Transmission Experimentale de la Maladie A Partir de Bovins Traites. ... Tous les 14 animaux ont séroconverti et l'analyse post-mortem a montré la présence des lésions chroniques dont des séquestres pulmonaires chez 4 d'entre ...

  18. Rat beta-LPH, gamma-LPH and beta-endorphin biosynthesized by isolated cells of pars intermedia and pars distalis

    International Nuclear Information System (INIS)

    Gianoulakis, C.; Seidah, N.G.; Routhier, R.; Chretien, M.

    1980-01-01

    Rats pars intermedia cells were incubated for 3 h with the following amino-acids: a) 35 S-methionine and 3 H-phenylalamine; b) 3 H-valine; and c) 3 H-valine and 3 H-lysine. Radioactive gamma-lipotropin, beta-lipotropin and beta-endorphin were purified on carboxy- methyl-cellulose and characterized by polyacrylamide disc gel electrophoresis af pH 4.5, molecular weight estimation and microsequencing. Rat gamma-lipotropin was shown to differ slightly from ovine gamma-lipotropin in its NH 2 -terminal amino acid sequence, in containing no methionine and having phenylalanine at position 6, valine at positions 13 and 27, and lysine at position 20. The same variations were observed in the sequence of rat beta-lipotropin, while rat beta-endorphin was shown to be identical to the ovine beta-endorphin. Following a 3-h pulse of rat pars distalis, the cells were extracted with care to avoid beta-lipotropin degradation by proteolytic enzymes. A peptide was purified and identified to be rat beta-endorphin, thus demonstrating that beta-endorphin is biosynthesized in pars distalis and is not an extraction artifact. (author)

  19. Efficacy and safety of the pars plana clip in the Ahmed valve device inserted via the pars plana in patients with refractory glaucoma

    Directory of Open Access Journals (Sweden)

    Manuel Diaz-Llopis

    2010-05-01

    Full Text Available Manuel Diaz-Llopis1,2,3, David Salom1,3, Salvador García-Delpech1,2,3, Patricia Udaondo1,3, Jose Maria Millan3,5, J Fernando Arevalo61Department of Ophthalmology, La Fe University Hospital of Valencia, Valencia, Spain; 2Department of Ophthalmology of the Valencia University, Valencia, Spain; 3Biomedical Network Research Centre on Rare Diseases (CIBERER, Valencia, Spain; 4Catholic University San Vicente Martir, Valencia, Spain; 5Department of Genetics, La Fe University Hospital of Valencia, Valencia, Spain; 6Clinica Oftalmologica Centro Caracas, Retina and VItreous Service, Caracas, DC, VenezuelaPurpose: To evaluate the efficacy and safety of the pars plana clip (PPC in the Ahmed valve tube inserted via the pars plana in patients with secondary refractory glaucomas.Methods: Prospective and interventional case series that included 10 patients with secondary refractory glaucoma. The pars plana vitrectomy and the implant of the modified tube were performed during the same surgery. Control of intraocular pressure (IOP and the development of intra- and postoperative complications were evaluated during the follow-up.Results: Follow-up time was twelve months in all the patients. Control of IOP was achieved in 90% of patients, and 70% needed no antiglaucoma treatment. The complications that occurred were transient hypotony in three cases, choroidal detachment in two cases, and one case of intraocular hemorrhage. No case of tube extrusion or tube kink was observed.Conclusions: Our data suggests that implantation of the Ahmed tube modified with the PPC via the pars plana is safe and effective in patients with secondary refractory glaucomas. Keywords: pars plana clip, Ahmed valve, refractory glaucoma, pars plana vitrectomy

  20. MODIS-derived daily PAR simulation from cloud-free images and its validation

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Liangfu; Gu, Xingfa; Tian, Guoliang [State Key Laboratory of Remote Sensing Science, Jointly Sponsored by Institute of Remote Sensing Applications of Chinese Academy of Sciences and Beijing Normal University, Beijing 100101 (China); The Center for National Spaceborne Demonstration, Beijing 100101 (China); Gao, Yanhua [State Key Laboratory of Remote Sensing Science, Jointly Sponsored by Institute of Remote Sensing Applications of Chinese Academy of Sciences and Beijing Normal University, Beijing 100101 (China); Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101 (China); Yang, Lei [State Key Laboratory of Remote Sensing Science, Jointly Sponsored by Institute of Remote Sensing Applications of Chinese Academy of Sciences and Beijing Normal University, Beijing 100101 (China); Jilin University, Changchun 130026 (China); Liu, Qinhuo [State Key Laboratory of Remote Sensing Science, Jointly Sponsored by Institute of Remote Sensing Applications of Chinese Academy of Sciences and Beijing Normal University, Beijing 100101 (China)

    2008-06-15

    In this paper, a MODIS-derived daily PAR (photosynthetically active radiation) simulation model from cloud-free image over land surface has been developed based on Bird and Riordan's model. In this model, the total downwelling spectral surface irradiance is divided into two parts: one is beam irradiance, and another is diffuse irradiance. The attenuation of solar beam irradiance comprises scattering by the gas mixture, absorption by ozone, the gas mixture and water vapor, and scattering and absorption by aerosols. The diffuse irradiance is scattered out of the direct beam and towards the surface. The multiple ground-air interactions have been taken into account in the diffuse irradiance model. The parameters needed in this model are atmospheric water vapor content, aerosol optical thickness and spectral albedo ranging from 400 nm to 700 nm. They are all retrieved from MODIS data. Then, the instantaneous photosynthetically available radiation (IPAR) is integrated by using a weighted sum at each of the visible MODIS wavebands. Finally, a daily PAR is derived by integration of IPAR. In order to validate the MODIS-derived PAR model, we compared the field PAR measurements in 2003 and 2004 against the simulated PAR. The measurements were made at the Qianyanzhou ecological experimental station, Chinese Ecosystem Research Network. A total of 54 days of cloud-free MODIS L1B level images were used for the PAR simulation. Our results show that the simulated PAR is consistent with field measurements, where the correlation coefficient of linear regression between calculated PAR and measured PAR is 0.93396. However, there were some uncertainties in the comparison of 1 km pixel PAR with the tower flux stand measurement. (author)

  1. Argon activation analysis, application to dating by the potassium-argon method; Analyse par activation de l'argon. Application a la datation par la methode potassium-argon

    Energy Technology Data Exchange (ETDEWEB)

    Dumesnil, P. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-07-01

    Activation analysis using radiogenic argon-40 has been applied to rock-dating by the K-Ar method. The argon is extracted from the sample, purified, activated to saturation in a flux of 2 X 10{sup 13} neutrons/cm{sup 2} sec{sup -1} and measured by gamma spectroscopy. The sensitivity obtained is such that it is possible to measure amounts of argon corresponding to age of a few thousand years only. However since it has not been possible to measure the amount of pollution of radiogenic argon by atmospheric argon with any accuracy, the measurable age limit is in fact of the order of MY. The method has been applied to basalts from the Mont-Dore region. The results obtained are in fairly good agreement with geological, stratigraphic and paleomagnetic data. (author) [French] L'analyse par activation de l'argon 40 radiogenique a ete appliquee a la datation des roches par la methode K-Ar. L'argon est extrait de l'echantillon, purifie, active a saturation dans un flux de 2.10{sup 13} neutrons.cm{sup -2}.s{sup -1} et mesure en spectrometrie gamma. La sensibilite obtenue est telle qu'il est possible de mesurer des quantites d'argon correspondant a des ages de quelques milliers d'annees seulement. Cependant la correction de pollution de l'argon radiogenique par l'argon atmospherique n'ayant pu etre etablie avec precision, la limite d'age mesurable pratique est de l'ordre de 1 Ma. La methode a ete appliquee aux basaltes de la region du Mont-Dore. Les ages obtenus sont en assez bon accord avec les donnees geologiques, stratigraphiques et paleomagnetiques. (auteur)

  2. 41 CFR 105-68.300 - What must I do before I enter into a covered transaction with another person at the next lower tier?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What must I do before I... Business with Other Persons § 105-68.300 What must I do before I enter into a covered transaction with....300 Public Contracts and Property Management Federal Property Management Regulations System (Continued...

  3. Vardarbība multiplikācijas filmā „Toms Džerijs”: pirmsskolēnu vecāki par bērnu skatīšanās paradumiem un iespējamajiem efektiem

    OpenAIRE

    Timšāne, Ērika

    2007-01-01

    Bakalaura darba temats ir „Vardarbība multiplikācijas filmā „Toms Džerijs”: pirmsskolēnu vecāki par bērnu skatīšanās paradumiem un iespējamajiem efektiem.” Pētījuma problēma ir vardarbība multiplikācijas filmā „Toms un Džerijs”, pirmsskolēnu izpratne pars saturu. Par teorētisko bāzi kalpo Alberta Banduras Sociālās iemācīšanās teorija. Tiek aplūkotas bērnu auditorijas īpatnības, intereses un efekti, ko izraisa agresija. Kontentanalīzes mērķis ir izpētīt desmit dažādu gadu „Toms un Džer...

  4. Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis

    NARCIS (Netherlands)

    Lin, Cong; von der Thüsen, Jan; Daalhuisen, Joost; ten Brink, Marieke; Crestani, Bruno; van der Poll, Tom; Borensztajn, Keren; Spek, C. Arnold

    2015-01-01

    Idiopathic pulmonary fibrosis is the most devastating diffuse fibrosing lung disease of unknown aetiology. Compelling evidence suggests that both protease-activated receptor (PAR)-1 and PAR-2 participate in the development of pulmonary fibrosis. Previous studies have shown that bleomycin-induced

  5. Elastic and inelastic scattering of 2 to 10 MeV protons by lithium isotopes; Diffusion elastique et inelastique des protons de 2 a 10 MeV par les isotopes du lithium

    Energy Technology Data Exchange (ETDEWEB)

    Laurat, M [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes

    1969-07-01

    A description is given of the experimental set-up which has been devised for carrying out spectrometric and absolute cross-section measurements on the reactions induced by protons accelerated in a 12 MeV Van de Graaff Tandem. The particles are detected by silicon junctions; the weight of the targets (about ten {mu}g/cm{sup 2}) is determined by the quartz method. The experimental equipment has been controlled by a study of proton scattering by lithium-6, and has made it possible to evaluate the elastic and inelastic scattering (1. level excitation) by lithium 7 of 2 to 9 MeV protons. The most probable spin and parity values for the six levels of {sup 8}Be between 19 and 25 MeV excitation energy have been determined from a knowledge of the observed structure. (author) [French] Nous decrivons le dispositif experimental mis au point pour effectuer les mesures de spectrometrie et de section efficace absolue pour les reactions induites par des protons acceleres par un Van de Graaff Tandem 12 MeV. Les particules sont detectees par des jonctions au silicium, le poids des cibles (de l'ordre d'une dizaine de {mu}g/cm{sup 2}), mesure par la methode du quartz. L'ensemble de l'appareillage a ete controle par l'etude de la diffusion des protons par le lithium 6, et nous a permis de preciser les diffusions elastiques et inelastiques (excitation du 1er niveau) des protons de 2 a 9 MeV par le lithium 7. La structure observee a permis de determiner les spin et parite les plus probables de six niveaux du {sup 8}Be entre 19 et 25 MeV d'energie d'excitation. (auteur)

  6. Elastic and inelastic scattering of 2 to 10 MeV protons by lithium isotopes; Diffusion elastique et inelastique des protons de 2 a 10 MeV par les isotopes du lithium

    Energy Technology Data Exchange (ETDEWEB)

    Laurat, M. [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes

    1969-07-01

    A description is given of the experimental set-up which has been devised for carrying out spectrometric and absolute cross-section measurements on the reactions induced by protons accelerated in a 12 MeV Van de Graaff Tandem. The particles are detected by silicon junctions; the weight of the targets (about ten {mu}g/cm{sup 2}) is determined by the quartz method. The experimental equipment has been controlled by a study of proton scattering by lithium-6, and has made it possible to evaluate the elastic and inelastic scattering (1. level excitation) by lithium 7 of 2 to 9 MeV protons. The most probable spin and parity values for the six levels of {sup 8}Be between 19 and 25 MeV excitation energy have been determined from a knowledge of the observed structure. (author) [French] Nous decrivons le dispositif experimental mis au point pour effectuer les mesures de spectrometrie et de section efficace absolue pour les reactions induites par des protons acceleres par un Van de Graaff Tandem 12 MeV. Les particules sont detectees par des jonctions au silicium, le poids des cibles (de l'ordre d'une dizaine de {mu}g/cm{sup 2}), mesure par la methode du quartz. L'ensemble de l'appareillage a ete controle par l'etude de la diffusion des protons par le lithium 6, et nous a permis de preciser les diffusions elastiques et inelastiques (excitation du 1er niveau) des protons de 2 a 9 MeV par le lithium 7. La structure observee a permis de determiner les spin et parite les plus probables de six niveaux du {sup 8}Be entre 19 et 25 MeV d'energie d'excitation. (auteur)

  7. Tank 241-BY-105 vapor sampling and analysis tank characterization report

    International Nuclear Information System (INIS)

    Huckaby, J.L.

    1995-01-01

    Tank BY-105 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. Tank BY-105 is on the Ferrocyanide Watch List. Samples were collected from Tank BY-105 using the vapor sampling system (VSS) on July 7, 1994 by WHC Sampling and Mobile Laboratories. The tank headspace temperature was determined to be 26 C. Air from the Tank BY-105 headspace was withdrawn via a heated sampling probe mounted in riser 10A, and transferred via heated tubing to the VSS sampling manifold. All heated zones of the VSS were maintained at approximately 65 C. Sampling media were prepared and analyzed by WHC, Oak Ridge National Laboratories, Pacific Northwest Laboratories, and Oregon Graduate Institute of Science and Technology through a contract with Sandia National Laboratories. The 46 tank air samples and 2 ambient air control samples collected are listed in Table X-1 by analytical laboratory. Table X-1 also lists the 10 trip blanks provided by the laboratories

  8. 40 CFR 2.105 - Exemption categories.

    Science.gov (United States)

    2010-07-01

    ... the mandatory disclosure requirements of 5 U.S.C. 552(a): (1)(i) Specifically authorized under... enforcement investigations or prosecutions if such disclosure could reasonably be expected to risk... for Disclosure of Records Under the Freedom of Information Act § 2.105 Exemption categories. (a) The...

  9. Relação da circunferência escrotal e parâmetros da qualidade do sêmen em touros da raça Nelore, PO

    Directory of Open Access Journals (Sweden)

    Silva Antonio Emidio Dias Feliciano

    2002-01-01

    Full Text Available Em 960 touros da raça Nelore, PO, de 11,4 a 135 meses de idade, pertencentes a fazendas localizadas nos Estados de São Paulo, Goiás e Pará, estudou-se a possível associação entre o tamanho da circunferência escrotal (CE e os parâmetros da qualidade do sêmen, motilidade progressiva (MOT e patologias espermáticas: defeitos maiores (DEFMAI, menores (DEFMEN e totais (DEFTOT. Os touros foram divididos por faixas etárias em: menores que 18, de 18 a 24, de 24 a 30, de 30 a 36 e maiores que 36 meses de idade. Este estudo foi realizado com a finalidade de obter tamanhos de CE que possam indicar o estatus funcional dos testículos, ou seja, a qualidade do sêmen, a serem utilizados para predizer o potencial reprodutivo dos animais destinados à seleção de reprodutores. Da correlação da CE com a MOT, por faixa etária, resultou uma associação (R=0,60; P<0,0001 destes parâmetros nos touros até 18 meses de idade, em que CEs acima de 26 cm indicaram sêmen de alta MOT (60 a 80%. As correlações entre CE e patologias espermáticas foram baixas e a maioria, negativa. Foi concluído, neste estudo, que nos touros jovens o tamanho da CE indica a qualidade do sêmen, portanto pode ser utilizado como um dos critérios na seleção de animais de alto potencial reprodutivo.

  10. Occupational radiation exposure at the self-shielded IBA CYCLONE 10/5, cyclotron of the Austin and Repatriation Medical Centre, Melbourne, Australia

    International Nuclear Information System (INIS)

    Tochon-Danguy, H.; Sachinidis, J.I.; U, P.; Egan, G.; Mukherjee, B.

    1999-01-01

    A series of health physics measurements was carried out at the IBA CYCLONE 10/5 Medical Cyclotron of the Austin and Repatriation Medical Centre, Melbourne. The neutron attenuation factor of the cyclotron shielding was estimated using the Superheated Bubble dosimeters. The neutron and gamma dose rates at various public access and radiation worker's area in the vicinity of the cyclotron facility were evaluated during the 11 C, 18 F, 13 N and 15 O production conditions. (authors)

  11. Activation of PAR-1/NADPH oxidase/ROS signaling pathways is crucial for the thrombin-induced sFlt-1 production in extravillous trophoblasts: possible involvement in the pathogenesis of preeclampsia.

    Science.gov (United States)

    Huang, Qi-Tao; Chen, Jian-Hong; Hang, Li-Lin; Liu, Shi-San; Zhong, Mei

    2015-01-01

    Preeclampsia was characterized by excessive thrombin generation in placentas and previous researches showed that thrombin could enhance soluble Fms-like tyrosine kinase 1 (sFlt-1) expression in first trimester trophoblasts. However, the detailed mechanism for the sFlt-1 over-production induced by thrombin was largely unknown. The purpose of this study was to explore the possible signaling pathway of thrombin-induced sFlt-1 production in extravillous trophoblasts (EVT). An EVT cell line (HRT-8/SVneo) was treated with various concentrations of thrombin. The mRNA expression and protein secretion of sFlt-1 in EVT were detected with real-time polymerase chain reaction and ELISA, respectively. The levels of intracellular reactive oxygen species (ROS) production were determined by DCFH-DA. Exposure of EVT to thrombin induced increased intracellular ROS generation and overexpression of sFlt-1 at both mRNA and protein levels in a dose dependent manner. Short interfering RNA (siRNA) directed against PAR-1 or apocynin (an inhibitor of NADPH oxidase) could decrease the intracellular ROS generation and subsequently suppressed the production of sFlt-1 at mRNA and protein levels. Our results suggested that thrombin increased sFlt-1 production in EVT via the PAR-1 /NADPH oxidase /ROS signaling pathway. This also highlights the PAR-1 / NADPH oxidase / ROS pathway might be a potential therapeutic target for the prevention of preeclampsia in the future. © 2015 S. Karger AG, Basel.

  12. Calibration of langmuir probes by a microwave method; Etalonnage des sondes de langmuir par une methode hyperfrequence

    Energy Technology Data Exchange (ETDEWEB)

    Consoli, T [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1960-07-01

    Measurements of the electronic density of a plasma between 10{sup 6} and 10{sup 8} e/cm{sup 3}, made by the Langmuir probe and by resonance frequency shift of a cavity are compared. (author) [French] On compare les mesures de la densite electronique d'un plasma peu dense 10{sup 6} < ne < 10{sup 8} e/cm{sup 3}, par sonde de Langmuir et par glissement de la frequence de resonance d'une cavite contenant le plasma. (auteur)

  13. Densité, morphologie urbaine et qualité de vie. Une approche par le projet

    OpenAIRE

    Occhiuto, Rita; Goossens, Marc; Fisher, Axel

    2013-01-01

    La recherche "Densification des tissus urbanisés en Wallonie: forme, acceptabilité et modalités pour accompagner la mutation des tissus bâtis" s'articule en plusieurs volets thématiques, parmi lesquels figure le volet "formes urbaines, modes d'habitat". Ce dernier volet est abordé selon deux approches parallèles et complémentaires qui se valident mutuellement: la première dite "par le projet" (approche qualitative et opérationnelle) et la seconde par analyse statistique et cartographique (ap...

  14. Modélisation multi-échelles en viscoplasticité endommageable de composites thermoplastiques renforcés par des fibres discontinues

    OpenAIRE

    ACHOUR, Nadia; CHATZIGEORGIOU, George; BONNAY, Kevin; MERAGHNI, Fodil

    2017-01-01

    Un nouveau modèle multi-échelles en régime viscoplastique endommageable est développé pour un composite à matrice polypropylène renforcé par des fibres de verre courtes. Basé sur l’approche en champs moyens de Mori Tanaka, il intègre une matrice viscoplastique modélisée par un modèle phénoménologique nommé par ses auteurs DSGZ et des fibres de verres modélisées par un comportement élastique linéaire. Le modèle multi-échelles permet d’intégrer la microstructure du composite préalablement carac...

  15. Contribution des causes de décès aux gains en espérance de vie à 65 ans au Canada et l’influence de leur profil par âge, 1979-2007

    DEFF Research Database (Denmark)

    Bergeron Boucher, Marie-Pier

    variation par âge des causes de décès influencent les tendances des taux de mortalité par cause. Les résultats montrent que les progrès de l’espérance de vie à 65 ans sont encore majoritairement dus à la diminution de la mortalité liée aux maladies cardiovasculaires. Toutefois, ces dernières causes de décès...... dans l’évolution de l’espérance de vie proviennent de modifications dans les tendances de certaines causes de décès et de leurs interactions. Cette étude analyse la contribution respective de certaines causes de décès aux changements observés de l’espérance de vie, mais aussi comment les profils de...... ne sont pas les seules à contribuer aux progrès en espérance de vie, puisque les taux de mortalité des dix principales causes de décès au Canada ont connu une diminution depuis 1979, malgré des profils de variation par âge différents....

  16. La lecture de Merleau-Ponty par Renaud Barbaras

    Czech Academy of Sciences Publication Activity Database

    Pechar, Jiří

    2015-01-01

    Roč. 11, č. 2 (2015), s. 1-6 ISSN 1336-6556 Institutional support: RVO:67985955 Keywords : Merleau-Ponty * Husserl * phenomenology * linguistics of Ferdinand de Saussure Subject RIV: AA - Philosophy ; Religion http://www.ostium.sk/sk/la-lecture-de-merleau-ponty-par-renaud-barbaras/

  17. River Mileages and Drainage Areas for Illinois Streams. Volume 2. Illinois River Basin.

    Science.gov (United States)

    1979-12-01

    52.2 WALNUT FORK L LIBERTY 53.1 WALKER BRANCH P LIBERTY 53.3 ROAn S06,TO?S,R05W LIBERTY 54.0 CURL CREEK L LIBERTY 54.4 ROAn S06,T02SR05W LIBERTY 34 QI...33TOI01N 5OW AUGUSTA T13.3 US HWY 24 AUGUSTA 14.4 TOPOGRAPHIC DIVIDE AUGUSTA WALKER BRANCH (MOUTH AT MCKEE CREEK MILE 53.1) ADAMS COUNTY 1.0 ROAD S07T2SRO5W...VERMILION R TRIR L LA SALLE 10.5 (ISGS GAGF 05555500 LOWELL 1278 411519 0A90044 LA SALLE 10.5 IL kT 178 LA SALLE 17.2 USGS GAGE 05555300 NEAR LEONORE

  18. Les paradoxes des distances dans la construction des identités alimentaires par acculturation

    Directory of Open Access Journals (Sweden)

    Marc Dedeire

    2008-03-01

    Full Text Available À partir d’une problématique issue d’observations et de lectures sur la mobilité des hommes, le(s distance(s et l’ancrage territorial, nous nous interrogeons sur les paradoxes de l’acculturation dans la (reconstruction des identités alimentaires. Pourquoi certaines populations développent-elles leur culture alimentaire locale dans des territoires d’accueil ? Quel est le rôle du migrant et de la distance sur cette diffusion appuyée par l’acculturation ? Et quelles sont les formes d’ancrages territoriaux expliquant les diffusions de certains produits locaux ?The authors base their research question on the observations and the literature concerning different forms of mobility of human beings and food products, distances and territorial anchoring. They further their analysis on the paradoxes of acculturation process that arise during the identity (reconstruction in the field of food consumption and eating habits. They focus on the place of cross-border migrations in the spreading of genuine country products and/or local eating specialities of the migrant populations in their host countries. What are the different definitions of distance(s that separate the migrant from its home country and from the host culture? What role dœs the migrant play in the spreading of these eating habits? How the acculturation process works? What are the different forms of territorial anchoring to explain the spreading of these genuine country food products?

  19. Activation of PAR-1/NADPH Oxidase/ROS Signaling Pathways is Crucial for the Thrombin-Induced sFlt-1 Production in Extravillous Trophoblasts: Possible Involvement in the Pathogenesis of Preeclampsia

    Directory of Open Access Journals (Sweden)

    Qi-tao Huang

    2015-03-01

    Full Text Available Backgrounds/Aims: Preeclampsia was characterized by excessive thrombin generation in placentas and previous researches showed that thrombin could enhance soluble Fms-like tyrosine kinase 1 (sFlt-1 expression in first trimester trophoblasts. However, the detailed mechanism for the sFlt-1 over-production induced by thrombin was largely unknown. The purpose of this study was to explore the possible signaling pathway of thrombin-induced sFlt-1 production in extravillous trophoblasts (EVT. Methods: An EVT cell line (HRT-8/SVneo was treated with various concentrations of thrombin. The mRNA expression and protein secretion of sFlt-1 in EVT were detected with real-time polymerase chain reaction and ELISA, respectively. The levels of intracellular reactive oxygen species (ROS production were determined by DCFH-DA. Results: Exposure of EVT to thrombin induced increased intracellular ROS generation and overexpression of sFlt-1 at both mRNA and protein levels in a dose dependent manner. Short interfering RNA (siRNA directed against PAR-1 or apocynin (an inhibitor of NADPH oxidase could decrease the intracellular ROS generation and subsequently suppressed the production of sFlt-1 at mRNA and protein levels. Conclusions: Our results suggested that thrombin increased sFlt-1 production in EVT via the PAR-1 /NADPH oxidase /ROS signaling pathway. This also highlights the PAR-1 / NADPH oxidase / ROS pathway might be a potential therapeutic target for the prevention of preeclampsia in the future.

  20. Precipitation of aluminum and magnesium secondary minerals from uranium mill raffinate (pH 1.010.5) and their controls on aqueous contaminants

    International Nuclear Information System (INIS)

    Robertson, Jared; Hendry, M. Jim; Essilfie-Dughan, J.; Chen, J.

    2016-01-01

    Models of geochemical controls on elements of concern (EOCs; e.g., As, Se, Mo, Ni) in U tailings are dominated by ferrihydrite. However, the evolution of aqueous concentrations of Al and Mg through the Key Lake (KL) U mill bulk neutralization process indicates that secondary Al and Mg minerals comprise a large portion of the tailings solids. X-ray diffraction, Al K-edge XAS, and TEM elemental mapping of solid samples collected from a pilot-scale continuous-flow synthetic raffinate neutralization system of the KL mill indicate the secondary Al–Mg minerals present include Mg–Al hydrotalcite, amorphous Al(OH)_3, and an amorphous hydrobasaluminite-type phase. The ferrihydrite present contains Al and may be more accurately described as Al–Fe(OH)_3. In the final combined tailings sample (pH 10.5) collected from the model experiments using raffinate with Al, Mg, and Fe, solid phase EOCs were associated with Al–Fe(OH)_3 and Mg–Al hydrotalcite. In model experiments using raffinate devoid of Fe, aqueous EOC concentrations decreased greatly at pH 4.0 (i.e., where ferrihydrite would precipitate) and largely remained in the solid phase when increased to the terminal pH of 10.5; this suggests Al–Mg minerals can control aqueous concentrations of EOCs in the raffinate in the absence of Fe. Maximum adsorption capacities for individual and mixtures of adsorbates by Mg–Al hydrotalcite were determined. A revised model of the geochemical controls in U mill tailings is presented in which Al and Mg minerals co-exist with Fe minerals to control EOC concentrations. - Highlights: • Simulated a U mill neutralization process to identify Al–Mg secondary mineralogy. • Identified AlOHSO_4, Al–Fe(OH)_3, Al(OH)_3, and Mg–Al hydrotalcite as precipitates. • Aqueous As, Ni, Mo, and Se concentrations controlled by Al–Mg minerals. • Experimental hydrotalcite uptake of As, Mo, and Se was comparable to ferrihydrite. • Updates the current model of aqueous contaminant

  1. Pulsed Neutron Studies of BeO-Natural Uranium Lattices; Etudes de Reseaux Uranium Naturel-Glucine, par la Methode des Neutrons Pulses; Issledovanie reshetok BeO-prirodnyj uran s pomoshch'yu impul'snykh nejtronov; Estudio de Reticulados de Beo-Uranio Natural con Ayuda de Neutrones Pulsados

    Energy Technology Data Exchange (ETDEWEB)

    Joshi, B. V.; Nargundkar, V. R.; Subbarao, K. [Atomic Energy Establishment Trombay, Bombay (India)

    1965-10-15

    verticalement dans des .canaux de section carree 5 x 5 cm dans un reseau carre dont le pas etait de 15 cm. Les bouffees de neutrons etaient produites par la reaction Be(d,n), la source de deuterons puises etant un accelerateur a cascade. Les detecteurs etaient des compteurs proportionnels au BF{sub 3}. Les harmoniques du lieu et du temps ont ete eliminees de la facon decrite par les auteurs dans un autre memoire presente au meme colloque. Les auteurs ont determine la constante de decroissance du mode fondamental pour plusieurs laplaciens, loin de l'etat critique. Dans ces calculs, ils ont tenu compte de l'effet de refroidissement par diffusion et de l'anisotropie. Ils ont determine toutes les constantes de diffusion et de multiplication en ajustant les donnees de trois manieres differentes par la methode des moindres carres. Ils ont obtenu le laplacien pour l'etat critique instantane en resolvant l'equation de la constante de decroissance pour {lambda} = 0. Les resultats definitifs qu'ils ont obtenus sont les suivants: Longueur de diffusion L = 15,2 cm Constante d'absorption {lambda}{sub 0} = 762, 5 s{sup -1} Coefficient de diffusion D = 1,761 * 105 cm{sup 2}/s Constante de refroidissement par diffusion C = -8,766 * 10{sup 5} cm{sup 4}/s Age {tau} = 150,7 cm{sup 2} Facteur de multiplication infini k{sub {infinity}} = 1,126 Laplacien pour l'etat critique instantane B{sup 2} = 3,00 * 10{sup -4} cm{sup -2}. (author) [Spanish] Los autores describen el empleo del metodo de los neutrones pulsados para determinar los parametros de difusion y las constantes de multiplicacion de diversos reticulados. Empleando este metodo, han obtenido los parametros de difusion y las constantes de multiplicacion en reticulados de BeO-uranio natural. Las barras de uranio empleadas medfan 2,92 cm de diametro, estaban revestidas de una capa de aluminio de 0,072 cm de espesor, y se hallaban colocadas verticalmente en canales de seccion cuadrada de 5 cm de lado, en un reticulado cuadrado de 15 cm de paso

  2. Le comportement des audités: quel effet sur la qualité de service rendu par les cabinets d’audit au Cameroun ?

    Directory of Open Access Journals (Sweden)

    Léopold Djoutsa Wamba

    2014-09-01

    Full Text Available La présente étude a pour ambition de vérifier s’il existe un lien empirique entre le comportement des audités et la qualité de l’audit au Cameroun. Nous avons à cet effet appréhendé la qualité de l’audit via les qualités de l’auditeur (sa compétence et son indépendance. En s’appuyant sur les analyses de classification et économétriques par la méthode de régression logistique sur des données recueillies par questionnaire auprès de 40 cabinets d’audits présents au Cameroun, les résultats montrent d’une part que la qualité de l’audit est plutôt altérée dans notre contexte. D’autre part, cette étude relève que la probabilité d’avoir un audit de qualité est d’autant plus grande lorsque les honoraires sont négociés à la hausse permanemment et, d’autant plus faible, si l’audité est absent lors du déroulement de la mission, ou s’il accuse des retards dans le paiement des honoraires ou encore, lorsqu’il n’a pas fourni à temps tous les documents nécessaires pour mener à bien la mission.

  3. 42 CFR 412.105 - Special treatment: Hospitals that incur indirect costs for graduate medical education programs.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Special treatment: Hospitals that incur indirect costs for graduate medical education programs. 412.105 Section 412.105 Public Health CENTERS FOR... SYSTEMS FOR INPATIENT HOSPITAL SERVICES Special Treatment of Certain Facilities Under the Prospective...

  4. 7 CFR 927.105 - Communications.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Communications. 927.105 Section 927.105 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Rules and Regulations Communications § 927.105 Communications. Unless otherwise prescribed in this...

  5. 20 CFR 416.105 - Administration.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Administration. 416.105 Section 416.105 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Introduction, General Provisions and Definitions § 416.105 Administration. The Supplemental...

  6. 20 CFR 438.105 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... private sector. Recipient includes all contractors, subcontractors at any tier, and subgrantees at any... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Definitions. 438.105 Section 438.105 Employees' Benefits SOCIAL SECURITY ADMINISTRATION RESTRICTIONS ON LOBBYING General § 438.105 Definitions...

  7. Par Pond vegetation status Summer 1995 -- Summary

    International Nuclear Information System (INIS)

    Mackey, H.E. Jr.; Riley, R.S.

    1996-01-01

    The water level of Par Pond was lowered approximately 20 feet in mid-1991 in order to protect downstream residents from possible dam failure suggested by subsidence on the downstream slope of the dam and to repair the dam. This lowering exposed both emergent and nonemergent macrophyte beds to drying conditions resulting in extensive losses. A survey of the newly emergent, shoreline aquatic plant communities of Par Pond began in June 1995, three months after the refilling of Par Pond to approximately 200 feet above mean sea level. These surveys continued in July, September, and late October, 1995. Communities similar to the pre-drawdown, Par Pond aquatic plant communities are becoming re-established. Emergent beds of maidencane, lotus, waterlily, and watershield are extensive and well developed. Cattail occurrence continued to increase during the summer, but large beds common to Par Pond prior to the drawdown have not formed. Estimates from SPOT HRV, remote sensing satellite data indicated that as much as 120 hectares of emergent wetlands vegetation may have been present along the Par Pond shoreline by early October, 1995. To track the continued development of macrophytes in Par Pond, future surveys throughout 1996 and 1997, along with the continued evaluation of satellite data to map the areal extent of the macrophyte beds of Par Pond, are planned

  8. Composition and variation of sediment bacterial and nirS-harboring bacterial communities at representative sites of the Bohai Gulf coastal zone, China.

    Science.gov (United States)

    Guan, Xiangyu; Zhu, Lingling; Li, Youxun; Xie, Yuxuan; Zhao, Mingzhang; Luo, Ximing

    2014-04-01

    With rapid urbanization, anthropogenic activities are increasingly influencing the natural environment of the Bohai Bay. In this study, the composition and variation of bacterial and nirS-harboring bacterial communities in the coastal zone sediments of the Bohai Gulf were analyzed using PCR-based clone libraries. A total of 95 genera were detected in the bacterial communities, with Proteobacteria (72.1 %), Acidobacteria (10.5 %), Firmicutes (1.7 %), Bacteroidetes (1.4 %), Chloroflexi (0.7 %) and Planctomycetes (0.7 %) being the dominated phyla. The NirS sequences were divided into nine Clusters (A-I). Canonical correlation analysis showed that the bacterial or denitrifying communities were correlated with different environmental factors, such as total organic carbon, total nitrogen, ammonium, sulfate, etc. Furthermore, bacterial communities' composition and diversity are influenced by oil exploration, sewage discharge and other anthropogenic activities in the coastal area of the Bohai Sea. Thus, this study provided useful information on further research on regional or global environmental control and restore.

  9. Notice of construction for the 105 KE encapsulation activity

    International Nuclear Information System (INIS)

    1993-03-01

    This is a Notice of Construction for the 105-KE Basin Fuel Encapsulation Activity. This Notice of Construction is being submitted to the State of Washington Department of Health pursuant to the Washington Administrative Code, 246-247, ''Radiation Protection--Air Emissions,'' as amended. The encapsulation activity will consist of all of the activities described in Section 1.3 as necessary to complete encapsulation of the fuel elements and sludge contained in the 105-KE Basin. The encapsulation activity will be carried out on the 105-KE Basin floor under a minimum of 3 m (10 ft) of water. The encapsulation activity.includes emptying irradiated fuel elements from the existing canisters stored in the 105-KE Basin, packaging.these fuel elements in new canisters, packaging sludge from previous fuel inventories and the current inventory in new canisters, capping these canisters of fuel elements and sludge, and returning the new canisters to the storage racks in the basin. The empty canisters will be cleaned and crushed underwater. Packaging and disposal of the crushed canisters will take place above the water

  10. Real-time X-ray microradiographic imaging and image correlation for local strain mapping in single trabecula under mechanical load

    Czech Academy of Sciences Publication Activity Database

    Doktor, Tomáš; Jiroušek, Ondřej; Kytýř, Daniel; Zlámal, Petr; Jandejsek, Ivan

    2011-01-01

    Roč. 6, č. 11 (2011), s. 7-12 ISSN 1748-0221. [International workshop on radiation imaging detectors /13./. Zurich, 03.07.2011-07.07.2011] R&D Projects: GA ČR(CZ) GAP105/10/2305 Institutional research plan: CEZ:AV0Z20710524 Keywords : pixelated detectors and associated VLSI electronics * X-ray radiography and digital radiography * digital image correlation * human trabecula Subject RIV: JJ - Other Materials Impact factor: 1.869, year: 2011 http://dx.doi.org/10.1088/1748-0221/6/11/C11007

  11. Microstructural control of Ti-46Al-7Nb-0.7Cr-0.2Ni-0.1Si alloy by heat treatment

    Czech Academy of Sciences Publication Activity Database

    Hasegawa, M.; Nomura, T.; Haga, H.; Dlouhý, Ivo; Fukutomi, H.

    2014-01-01

    Roč. 105, č. 11 (2014), s. 1075-1083 ISSN 1862-5282 Institutional support: RVO:68081723 Keywords : titanium aluminides * phase transformation * microstructure Subject RIV: JG - Metallurgy Impact factor: 0.639, year: 2014 http://www.hanser-elibrary.com/doi/abs/10.3139/146.111115

  12. MODÉLISATION DES FLUX DE CHALEUR GÉNÉRÉS PAR FROTTEMENT GLISSANT DANS UN CONTACT CUIVRE-ACIER TRAVERSÉ PAR UN COURANT ÉLECTRIQUE

    Directory of Open Access Journals (Sweden)

    A BOUCHOUCHA

    2001-06-01

    Full Text Available Le problème de la conduction de la chaleur dans un contact électrique glissant cuivre–acier est étudié. Le couple fonctionne dans des conditions atmosphériques et est donc refroidi par convection naturelle à travers les faces latérales. En utilisant l'équation de la chaleur, un modèle de calcul de la température interfaciale a été élaboré. A l'aide de la méthode des volumes finis, les résultats de la température en fonction de la charge normale, la vitesse de glissement et le courant électrique sont donnés. Une comparaison avec la méthode d'Archard est faite. Les résultats montrent une bonne concordance. Une discussion globale du modèle élaboré et son application dans les contacts électriques glissants a été dégagée.

  13. Protease-activated receptor 2 (PAR2) is upregulated by Acanthamoeba plasminogen activator (aPA) and induces proinflammatory cytokine in human corneal epithelial cells.

    Science.gov (United States)

    Tripathi, Trivendra; Abdi, Mahshid; Alizadeh, Hassan

    2014-05-29

    Acanthamoeba plasminogen activator (aPA) is a serine protease elaborated by Acanthamoeba trophozoites that facilitates the invasion of trophozoites to the host and contributes to the pathogenesis of Acanthamoeba keratitis (AK). The aim of this study was to explore if aPA stimulates proinflammatory cytokine in human corneal epithelial (HCE) cells via the protease-activated receptors (PARs) pathway. Acanthamoeba castellanii trophozoites were grown in peptone-yeast extract glucose for 7 days, and the supernatants were collected and centrifuged. The aPA was purified using the fast protein liquid chromatography system, and aPA activity was determined by zymography assays. Human corneal epithelial cells were incubated with or without aPA (100 μg/mL), PAR1 agonists (thrombin, 10 μM; TRAP-6, 10 μM), and PAR2 agonists (SLIGRL-NH2, 100 μM; AC 55541, 10 μM) for 24 and 48 hours. Inhibition of PAR1 and PAR2 involved preincubating the HCE cells for 1 hour with the antagonist of PAR1 (SCH 79797, 60 μM) and PAR2 (FSLLRY-NH2, 100 μM) with or without aPA. Human corneal epithelial cells also were preincubated with PAR1 and PAR2 antagonists and then incubated with or without PAR1 agonists (thrombin and TRAP-6) and PAR2 agonists (SLIGRL-NH2 and AC 55541). Expression of PAR1 and PAR2 was examined by quantitative RT-PCR (qRT-PCR), flow cytometry, and immunocytochemistry. Interleukin-8 expression was quantified by qRT-PCR and ELISA. Human corneal epithelial cells constitutively expressed PAR1 and PAR2 mRNA. Acanthamoeba plasminogen activator and PAR2 agonists significantly upregulated PAR2 mRNA expression (1- and 2-fold, respectively) (P aPA, and PAR2 agonists induced PAR2 mRNA expression in HCE cells (P aPA, significantly upregulated PAR1 mRNA expression, which was significantly inhibited by PAR1 antagonist in HCE cells. Acanthamoeba plasminogen activator and PAR2 agonists stimulated IL-8 mRNA expression and protein production, which is significantly diminished by PAR2 antagonist

  14. 7 CFR 3018.105 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... services in the private sector. (o) Recipient includes all contractors, subcontractors at any tier, and... 7 Agriculture 15 2010-01-01 2010-01-01 false Definitions. 3018.105 Section 3018.105 Agriculture... AGRICULTURE NEW RESTRICTIONS ON LOBBYING General § 3018.105 Definitions. For purposes of this part: (a) Agency...

  15. 9 CFR 3.105 - Feeding.

    Science.gov (United States)

    2010-01-01

    ... Mammals Animal Health and Husbandry Standards § 3.105 Feeding. (a) The food for marine mammals must be... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Feeding. 3.105 Section 3.105 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL...

  16. 13 CFR 500.105 - Staff.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Staff. 500.105 Section 500.105... LOAN PROGRAM Board Procedures § 500.105 Staff. (a) Executive Director. The Executive Director of the... direction with respect to the administration of the Board's actions, directs the activities of the staff...

  17. 13 CFR 400.105 - Staff.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Staff. 400.105 Section 400.105... Board Procedures § 400.105 Staff. (a) Executive Director. The Executive Director of the Board advises... with respect to the administration of the Board's actions, directs the activities of the staff, and...

  18. 22 CFR 311.105 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... services in the private sector. (o) Recipient includes all contractors, subcontractors at any tier, and... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Definitions. 311.105 Section 311.105 Foreign Relations PEACE CORPS NEW RESTRICTIONS ON LOBBYING General § 311.105 Definitions. For purposes of this part...

  19. The Trojan Horse Method application on the 10B(p,α0)7Be reaction cross section measurements

    Science.gov (United States)

    Cvetinović, A.; Spitaleri, C.; Spartá, R.; Rapisarda, G. G.; Puglia, S. M.; La Cognata, M.; Cherubini, S.; Guardo, G. L.; Gulino, M.; Lamia, L.; Pizzone, R. G.; Romano, S.; Sergi, M. L.

    2018-01-01

    The 10B(p,α0)7Be reaction cross section has been measured in an wide energy range from 2.2 MeV down to 3 keV in a single experiment applying THM. Optimized experimental set-up ensured good energy resolution leading to a good separation of α0 and α1 contributions to the cross section coming from the 7Be ground and first excited state, respectively.

  20. Adoption d'innovations agricoles par le truchement de services ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    L'agriculture est le fer de lance de nombreuses économies en développement, mais la capacité des petits agriculteurs privés de ressources à adopter des innovations agricoles est freinée par le manque d'accès à des services financiers adéquats. Des experts internationaux estiment qu'il existe un manque à gagner ...

  1. Hypersensitivity Induced by Activation of Spinal Cord PAR2 Receptors Is Partially Mediated by TRPV1 Receptors

    Czech Academy of Sciences Publication Activity Database

    Mrózková, Petra; Špicarová, Diana; Paleček, Jiří

    2016-01-01

    Roč. 11, č. 10 (2016), č. článku e0163991. E-ISSN 1932-6203 R&D Projects: GA ČR(CZ) GA15-11138S; GA MŠk(CZ) LH15279; GA ČR(CZ) GBP304/12/G069; GA MŠk(CZ) ED1.1.00/02.0109 Institutional support: RVO:67985823 Keywords : PAR2 * TRP * neuropathy * spinal cord Subject RIV: FH - Neurology Impact factor: 2.806, year: 2016

  2. Modification de la surface du cuivre par implantation ionique par source plasma (IISP): applications à l’érosion cathodique dans les systèmes à arcs

    OpenAIRE

    Roy, F

    2006-01-01

    L’érosion cathodique est un phénomène bien connu qui limite la durée de vie de l’électrode négative dans les systèmes à arcs. Dans le présent mémoire, nous avons tenté de voir si la formation de précipités nanométriques d’oxyde de cuivre pouvait réduire l’érosion cathodique nécessaire au maintien de l’arc en mode thermo-champ (T-F). Les dits précipités ont été produits par implantation ionique par source plasma (IISP). Avec l’aide de techniques de caractérisation telle que la microscopie à fo...

  3. Ouvrages en terre renforcés par géosynthétiques, sollicités localement en tête : expérimentation et méthode de calculs

    OpenAIRE

    Haza , Elisabeth

    1997-01-01

    Les massifs en terre renforcés par géosynthétiques, à parement souple, sont couramment utilisés en France pour leur fonction de soutènement. L'étude présentée dans ce mémoire se focalise sur leur capacité à remplir également la fonction de portance lorsque le massif est chargé localement en tête. L'ouvrage rassemble ainsi toutes les fonctions d'une culée de pont. Une expérimentation en vraie grandeur est présentée en détail (programme GAR.D.E.N.) : deux différents profils instrumentés sont me...

  4. Investigation of flammable gas and thermal safety issues for retrieval of waste from Tank 241-AN-105

    Energy Technology Data Exchange (ETDEWEB)

    Caley, S.M.; Stewart, C.W.; Antoniak, Z.I.; Cuta, J.M.; Mahoney, L.A.; Panisko, F.E.

    1998-09-01

    The primary purpose of this report is to identify and resolve some of the flammable gas and thermal safety issues potentially associated with the retrieval of waste from Tank 241-AN-105 (AN-105), which is the first double-shell tank scheduled for waste retrieval at Hanford. The planned retrieval scenario includes the following steps in AN-105: (1) degas the tank using two submerged mixing pumps, (2) turn off the mixer pump(s) and allow any suspended solids to settle, (3) decant the supernatant to the intermediate feed staging tank(s) (IFSTs) (AP-102 and/or AP-104) using water/caustic dilution at the transfer pump inlet, (4) add the remaining dilution water/caustic to the slurry remaining in AN-105, (5) mix the tank with the mixer pump(s) until the soluble solids dissolve, (6) turn off the mixer pump(s) and let the insoluble solids settle, and (7) decant the new supernatant to the IFST(s), leaving the insoluble solids behind. Three waste retrieval safety issues are addressed in this report. They are (1) the controlled degassing of AN-105 to ensure that the headspace remains <25% of the lower flammability limit (LFL), (2) an assessment of how dissolved gas (mainly ammonia) released during the transfer of the supernatant in AN-105 to the IFSTs and the water/caustic dilution of the remaining slurry in AN-105 will affect the flammability in these tanks; and (3) an assessment of the maximum waste temperatures that might occur in AN-105 during retrieval operations.

  5. Investigation of flammable gas and thermal safety issues for retrieval of waste from Tank 241-AN-105

    International Nuclear Information System (INIS)

    Caley, S.M.; Stewart, C.W.; Antoniak, Z.I.; Cuta, J.M.; Mahoney, L.A.; Panisko, F.E.

    1998-09-01

    The primary purpose of this report is to identify and resolve some of the flammable gas and thermal safety issues potentially associated with the retrieval of waste from Tank 241-AN-105 (AN-105), which is the first double-shell tank scheduled for waste retrieval at Hanford. The planned retrieval scenario includes the following steps in AN-105: (1) degas the tank using two submerged mixing pumps, (2) turn off the mixer pump(s) and allow any suspended solids to settle, (3) decant the supernatant to the intermediate feed staging tank(s) (IFSTs) (AP-102 and/or AP-104) using water/caustic dilution at the transfer pump inlet, (4) add the remaining dilution water/caustic to the slurry remaining in AN-105, (5) mix the tank with the mixer pump(s) until the soluble solids dissolve, (6) turn off the mixer pump(s) and let the insoluble solids settle, and (7) decant the new supernatant to the IFST(s), leaving the insoluble solids behind. Three waste retrieval safety issues are addressed in this report. They are (1) the controlled degassing of AN-105 to ensure that the headspace remains <25% of the lower flammability limit (LFL), (2) an assessment of how dissolved gas (mainly ammonia) released during the transfer of the supernatant in AN-105 to the IFSTs and the water/caustic dilution of the remaining slurry in AN-105 will affect the flammability in these tanks; and (3) an assessment of the maximum waste temperatures that might occur in AN-105 during retrieval operations

  6. La preuve par le nombre

    Directory of Open Access Journals (Sweden)

    Hélène Verdier

    2012-04-01

    Full Text Available S’il en était besoin, la question des usages et de la finalité des résultats de l’inventaire général pourrait être abordée par le nombre : nombre d’œuvres répertoriées, de communes inventoriées, de clichés photographiques réalisés, de dossiers, de consultations des notices dans les bases de données… Les additions aujourd’hui sont éloquentes, mais elles laissent dans l’ombre le rôle de l’inventaire qui, en mettant en œuvre une démarche systématique de connaissance, participe à l’ identificatio...

  7. Solar PAR and UVR modify the community composition and photosynthetic activity of sea ice algae.

    Science.gov (United States)

    Enberg, Sara; Piiparinen, Jonna; Majaneva, Markus; Vähätalo, Anssi V; Autio, Riitta; Rintala, Janne-Markus

    2015-10-01

    The effects of increased photosynthetically active radiation (PAR) and ultraviolet radiation (UVR) on species diversity, biomass and photosynthetic activity were studied in fast ice algal communities. The experimental set-up consisted of nine 1.44 m(2) squares with three treatments: untreated with natural snow cover (UNT), snow-free (PAR + UVR) and snow-free ice covered with a UV screen (PAR). The total algal biomass, dominated by diatoms and dinoflagellates, increased in all treatments during the experiment. However, the smaller biomass growth in the top 10-cm layer of the PAR + UVR treatment compared with the PAR treatment indicated the negative effect of UVR. Scrippsiella complex (mainly Scrippsiella hangoei, Biecheleria baltica and Gymnodinium corollarium) showed UV sensitivity in the top 5-cm layer, whereas Heterocapsa arctica ssp. frigida and green algae showed sensitivity to both PAR and UVR. The photosynthetic activity was highest in the top 5-cm layer of the PAR treatment, where the biomass of the pennate diatom Nitzschia frigida increased, indicating the UV sensitivity of this species. This study shows that UVR is one of the controlling factors of algal communities in Baltic Sea ice, and that increased availability of PAR together with UVR exclusion can cause changes in algal biomass, photosynthetic activity and community composition. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  8. Avis 6 sur la formation à et par la recherche

    OpenAIRE

    Centre de Coopération Internationale en Recherche Agronomique pour le Développement

    2015-01-01

    La formation à et par la recherche s’appuie sur la démarche scientifique, les savoirs, les connaissances à transmettre, tout autant que l’acquisition de compétences en gestion de projet, de capacités au travail en équipe, d’une ouverture d’esprit qui favorisera la créativité. Elle doit permettre de prendre conscience de la responsabilité endossée par la communauté scientifique vis-à-vis de la société et de l’environnement, mais aussi préparer l’avenir professionnel de celle ou de celui qu...

  9. 24 CFR 87.105 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... services in the private sector. (o) Recipient includes all contractors, subcontractors at any tier, and... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Definitions. 87.105 Section 87.105... RESTRICTIONS ON LOBBYING General § 87.105 Definitions. For purposes of this part: (a) Agency, as defined in 5 U...

  10. L'initiative Agua Limpia para Perú est dirigée par un ancien titulaire ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    9 juil. 2014 ... Au Pérou, de nombreuses sources d'eau sont contaminées par de ... l'accès à une eau propre et la formation sur l'assainissement, les eaux usées et les ... par AguaSAN Perú aux fins du traitement des eaux (en espagnol).

  11. Estrutura de florestas secundárias após dois diferentes sistemas agrícolas no nordeste do estado do Pará, Amazônia Oriental Structure of secondary forests after two different systems of land use in the northeastern Pará state, Brazil

    Directory of Open Access Journals (Sweden)

    Mauro Antônio Cavaleiro de Macedo Rodrigues

    2007-01-01

    Full Text Available O objetivo deste trabalho foi caracterizar e comparar a estrutura de florestas secundárias com quatro anos de idade, que foram formadas após a utilização de dois diferentes sistemas de eliminação da cobertura vegetal - o sistema alternativo (SA que tritura a biomassa e o sistema tradicional (ST que utiliza o fogo. O estudo foi conduzido na região Bragantina que está localizada no nordeste do Pará. Para tal, foram selecionadas três áreas amostrais para cada sistema de uso da terra. Dentro de cada área amostral foram alocadas aleatoriamente quatro parcelas de 15 m² (3 x 5 m, totalizando 60 m² por área de estudo e 180 m² por sistema de uso. Foi encontrada uma diversidade média (H' de 2,94 para o SA e 3,32 para o ST, a densidade média foi 459.556 ind. ha-1 no SA e 466.833 ind. ha-1 no ST, a área basal do estrato superior do SA foi de 8,48 m² ha-1 e a do ST 3,07 m² ha-1, a biomassa seca estimada para o SA foi de 6,68 ton ha-1 e 2,80 ton ha-1 para o ST. Ocorreram diferenças estatísticas (ANOVA; P The objective of this study was to characterize and compare the structure of 4-year old secondary forests that were established after the use of two different systems of elimination of forest coverage: i the alternative system (SA on which plant biomass is only triturated, and ii the traditional system (ST which uses fire. The study was conducted out in the Bragantina area, northeastern Pará state, Brazil. For each land use system we selected three areas in which four 15-m² (3 X 5 m plots were randomly established to. Mean diversity (H' was of 2.94 for SA and 3.32 for ST, mean density was 459,556 ind. ha-1 in SA and 466,833 ind. ha-1 in ST, mean basal area of the superior stratum in SA was 8.48 m² ha-1 and the one of ST was 3.07 m² ha-1. There were statistical differences (ANOVA; P < 0.05 in vertical structure parameters and biomass. We conclude that SA management technique facilitates the development of the structure arboreal

  12. Les déséquilibres biologiques provoqués par les traitements pesticides de la plante

    Directory of Open Access Journals (Sweden)

    F. CHABOUSSOU

    2016-10-01

    Full Text Available L'influence qu'exercent les pesticides sur la physiologie et la biochimie des végétaux peut se répercuter sur les déprédateurs vivant aux dépens de ceux-ci. La présente étude est consacrée aux effets opérés dans ce sens par le DDT, le parathion et le carbaryl à l'égard de l'araignée rouge (Panonychus ulmi Koch, d'Eotetranychus carpini f. vitis Dosse et de Tetranychus urticae Koch sur vigne. Les trois insecticides favorisent le développement de ces acariens à la suite de modifications biochimiques de la plante qui sont analysées. Les fongicides zinèbe, manèbe et propinèbe exercent également une action sur le végétal qui devient alors plus sensible aux attaques de l'oïdium de la vigne. L'auteur souligne toute l'importance qu'il y a à tenir compte de ces phénomènes lors de la mise en œuvre de programmes de lutte intégrée.

  13. Epuration des effluents industriels par électroflottation Belkacem ...

    African Journals Online (AJOL)

    étudié la séparation de quelques métaux lourds tels que le fer, le nickel, ... the separation of some heavy metals such as iron, nickel, copper, zinc, lead and ... généralement basées sur l'adsorption (par ... Différents essais de concentration en.

  14. Measures and modelling of PAR (photosynthetically-active radiation) for the Northeast of Brazil; Medidas e modelagem da radiacao PAR (photosynthetically-active radiation) para o nordeste do Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Tiba, Chigueru; Leal, Sergio da S.A. [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Dept. de Energia Nuclear], e-mail: tiba@rce.neoline.com.br

    2004-07-01

    Photosynthetically active solar radiation, known by its acronym in the English language as PAR, is the principal driving force of innumerable biological and physical processes related to biomass production, such as, the evolution of vegetal covering, agricultural productivity, and countless environment aspects, among others. Unfortunately in Brazil and particularly in the Northeast of Brazil, the PAR radiation measures are not a routine part of meteorological station measures, and therefore are still rarer than solar irradiation measures. In this context, a station was installed in Recife, Pernambuco in 2003, to carry out simultaneous measures of daily solar irradiation and PAR irradiation, which permits the modelling and valuation of the relationship between these two parameters and thus makes the estimation of PAR radiation possible, where there used to be only information on solar irradiation. Three others stations are being installed, one on Fernando de Noronha-PE, another in Pesqueira-PE, and the other in Xingo-SE, which complete a group of 4 between Latitudes 8 deg and 10 deg South and Longitudes 34 deg to 38 deg West, each having differentiated Equatorial Climates: island maritime, continental maritime, sylvan (Agreste) and semi-arid. (author)

  15. 24 CFR 51.105 - Exceptions.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Exceptions. 51.105 Section 51.105... ENVIRONMENTAL CRITERIA AND STANDARDS Noise Abatement and Control § 51.105 Exceptions. (a) Flexibility for non... acceptability standard of 65 decibels, the Acceptable Zone may be shifted to Ldn 70 on a case-by-case basis if...

  16. 14 CFR 1215.105 - Delivery of user data.

    Science.gov (United States)

    2010-01-01

    ... SATELLITE SYSTEM (TDRSS) Use and Reimbursement Policy for Non-U.S. Government Users § 1215.105 Delivery of... determined by NASA in the form of one or more digital or analog bit streams synchronized to associated clock...

  17. Keratometric alterations following the 25-gauge transconjunctival sutureless pars plana vitrectomy versus the conventional pars plana vitrectomy.

    Science.gov (United States)

    Citirik, Mehmet; Batman, Cosar; Bicer, Tolga; Zilelioglu, Orhan

    2009-09-01

    To assess the alterations in keratometric astigmatism following the 25-gauge transconjunctival sutureless pars plana vitrectomy versus the conventional pars plana vitrectomy. Sixteen consecutive patients were enrolled into the study. Conventional vitrectomy was applied to eight of the cases and 25-gauge transconjunctival sutureless vitrectomy was performed in eight patients. Keratometry was performed before and after the surgery. In the 25-gauge transconjunctival sutureless pars plana vitrectomy group, statistically significant changes were not observed in the corneal curvature in any post-operative follow-up measurement (p > 0.05); whereas in the conventional pars plana vitrectomy group, statistically significant changes were observed in the first postoperative day (p = 0.01) and first postoperative month (p = 0.03). We noted that these changes returned to baseline in three months (p = 0.26). Both 25-gauge transconjunctival sutureless and conventional pars plana vitrectomy are effective surgical modalities for selected diseases of the posterior segment. Surgical procedures are critical for the visual rehabilitation of the patients. The post-operative corneal astigmatism of the vitrectomised eyes can be accurately determined at least two months post-operatively.

  18. Investigation of aluminium and manganese uptake in Congolese flora by activation analysis; Recherche d'accumulateurs D’ Aluminium Et De Manganese Dans La Flore Congolaise Par La Methode D'Analyse Par Activation

    Energy Technology Data Exchange (ETDEWEB)

    Evrard, C.; Roels, J.; Pauwels, L.; Pollak, H. [Centre nucléaire TRICO, Kinshasa (Congo, The Democratic Republic of the); Université Lovanium, Kinshasa (Congo, The Democratic Republic of the)

    1970-01-15

    It is known that certain plants accumulate one or more elements in their tissues. This characteristic can make a valuable contribution to the taxonomy of groups, families and even of species. The ecology characteristic of each species may also be demonstrated by the accumulation of certain elements. Soil acidity can have a strong effect on accumulation. High acidity favours the accumulation of manganese, for example. The authors have endeavoured to perfect a technique of analysis based on neutron activation (nondestructive). Thermal neutron activation is carried out in the TRIGA Mk I reactor of the TRICO Nuclear Centre, which has a flux of about 10{sup 11}n cm{sup -2} s{sup -1}. Activation analysis is quicker than chemical methods and has the additional advantage that it can be used for small quantities of plant material. At least forty species of local plants have been tested. In addition to these specific tests, we have analysed leaves from trees of a given species growing in different soils, in order to get some idea of individual variations from one plant to another. (author) [French] Il est connu que certaines plantes accumulent un ou plusieurs éléments dans leurs tissus. Cette particularité peut apporter une précieuse contribution à la taxonomie des groupes, des familles ou même des espèces. L'écologie propre â chaque espèce peut aussi être mise en évidence par l'accumulation de certains éléments. Le degré d'acidité du sol, par exemple, peut fortement influencer cette accumulation. Dans le cas de manganèse, une forte acidité du sol favorise l'accumulation de cet élément. Les auteurs ont cherché à mettre au point une méthode d'analyse par activation neutronique (non destructive). Les activations aux neutrons thermiques ont été effectuées dans le réacteur TRIGA Mk I du Centre nucléaire TRICO, dans un flux d'environ 10{sup 11} n cm{sup -2} sec{sup -1}. Comparée à la méthode chimique, l'analyse par activation est plus rapide et peut

  19. Centromere pairing by a plasmid-encoded type I ParB protein

    DEFF Research Database (Denmark)

    Ringgaard, Simon; Löwe, Jan; Gerdes, Kenn

    2007-01-01

    The par2 locus of Escherichia coli plasmid pB171 encodes two trans-acting proteins, ParA and ParB, and two cis-acting sites, parC1 and parC2, to which ParB binds cooperatively. ParA is related to MinD and oscillates in helical structures and thereby positions ParB/parC-carrying plasmids regularly......, hence identifying the N terminus of ParB as a requirement for ParB-mediated centromere pairing. These observations suggest that centromere pairing is an important intermediate step in plasmid partitioning mediated by the common type I loci....

  20. Infection par le VIH chez les patientes atteintes de cancer du sein en ...

    African Journals Online (AJOL)

    L'objectif était de déterminer la prévalence de l'infection à VIH chez les patientes atteintes de cancer du sein et de comparer les caractéristiques anatomocliques et thérapeutiques de ces cancers du sein par rapports aux patientes non infectées par le VIH. Il s'agissait d'une étude rétrospective et analytique comparant les ...

  1. Tank 241-C-105 tank characterization plan

    International Nuclear Information System (INIS)

    Schreiber, R.D.

    1994-01-01

    This document is a plan which serves as the contractual agreement between the Characterization Program, Sampling Operations, WHC 222-S Laboratory, and PNL 325 Analytical Chemistry Laboratory. The scope of this plan is to provide guidance for the sampling and analysis of samples from tank 241-C-105

  2. CFD analysis of PAR performance as function of inlet design

    International Nuclear Information System (INIS)

    Park, Kweonha; Khor, Chong Lee

    2016-01-01

    Highlights: • The new concept of PAR (passive autocatalytic recombiner) was proposed and analyzed. • Guidance wall was added at the bottom of PAR to enhance the flow rate through the catalyst. • The new concept of PAR was proved to have a better hydrogen removal performance. - Abstract: Passive autocatalytic recombiner (PAR) is very useful hydrogen mitigation measurement. It is widely implemented in the current and advanced light water reactors (ALWRs). The design of the PARs should be optimized for the specific use under severe accident scenarios. Several techniques and innovations have been fused into the PAR, as an effort to increase its efficiency of hydrogen mitigation. This study proposes different concepts of PAR, which applied some changes to the honeycomb catalyst PAR made by the Korea Nuclear Technology (KNT) Inc. Two slices of plate are added to the bottom of PAR model, which intended to act as a reflection wall and promote the gas flow into PAR. Hydrogen volume fraction was given 4 vol. % which tested by KNT to investigate the performance of PAR in different direction gas flow conditions to see maximum hydrogen recombination rate. The new concept of PAR was proved to have a better hydrogen removal performance compared to the original honeycomb catalyst PAR.

  3. CFD analysis of PAR performance as function of inlet design

    Energy Technology Data Exchange (ETDEWEB)

    Park, Kweonha, E-mail: khpark@kmou.ac.kr [Division of Mechanical and Energy systems Engineering, Korea Maritime University, Dongsam-dong, Yeongdo-gu, Busan 606-791 (Korea, Republic of); Khor, Chong Lee, E-mail: itachi_829@hotmail.com [Department of Mechanical Engineering, Korea Maritime University (Korea, Republic of)

    2016-01-15

    Highlights: • The new concept of PAR (passive autocatalytic recombiner) was proposed and analyzed. • Guidance wall was added at the bottom of PAR to enhance the flow rate through the catalyst. • The new concept of PAR was proved to have a better hydrogen removal performance. - Abstract: Passive autocatalytic recombiner (PAR) is very useful hydrogen mitigation measurement. It is widely implemented in the current and advanced light water reactors (ALWRs). The design of the PARs should be optimized for the specific use under severe accident scenarios. Several techniques and innovations have been fused into the PAR, as an effort to increase its efficiency of hydrogen mitigation. This study proposes different concepts of PAR, which applied some changes to the honeycomb catalyst PAR made by the Korea Nuclear Technology (KNT) Inc. Two slices of plate are added to the bottom of PAR model, which intended to act as a reflection wall and promote the gas flow into PAR. Hydrogen volume fraction was given 4 vol. % which tested by KNT to investigate the performance of PAR in different direction gas flow conditions to see maximum hydrogen recombination rate. The new concept of PAR was proved to have a better hydrogen removal performance compared to the original honeycomb catalyst PAR.

  4. Par Pond Fish, Water, and Sediment Chemistry

    International Nuclear Information System (INIS)

    Paller, M.H.; Wike, L.D.

    1996-06-01

    The objectives of this report are to describe the Par Pond fish community and the impact of the drawdown and refill on the community, describe contaminant levels in Par Pond fish, sediments, and water and indicate how contaminant concentrations and distributions were affected by the drawdown and refill, and predict possible effects of future water level fluctuations in Par Pond

  5. Par Pond Fish, Water, and Sediment Chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Paller, M.H. [Westinghouse Savannah River Company, AIKEN, SC (United States); Wike, L.D.

    1996-06-01

    The objectives of this report are to describe the Par Pond fish community and the impact of the drawdown and refill on the community, describe contaminant levels in Par Pond fish, sediments, and water and indicate how contaminant concentrations and distributions were affected by the drawdown and refill, and predict possible effects of future water level fluctuations in Par Pond.

  6. Concerning the dynamic instability of actin homolog ParM

    International Nuclear Information System (INIS)

    Popp, David; Yamamoto, Akihiro; Iwasa, Mitsusada; Narita, Akihiro; Maeda, Kayo; Maeda, Yuichiro

    2007-01-01

    Using in vitro TIRF- and electron-microscopy, we reinvestigated the dynamics of native ParM, a prokaryotic DNA segregation protein and actin homolog. In contrast to a previous study, which used a cysteine ParM mutant, we find that the polymerization process of wild type ATP-ParM filaments consists of a polymerization phase and a subsequent steady state phase, which is dynamically unstable, like that of microtubules. We find that the apparent bidirectional polymerization of ParM, is not due to the intrinsic nature of this filament, but results from ParM forming randomly oriented bundles in the presence of crowding agents. Our results imply, that in the bacterium, ParM filaments spontaneously form bipolar bundles. Due to their intrinsic dynamic instability, ParM bundles can efficiently 'search' the cytoplasmic lumen for DNA, bind it equally well at the bipolar ends and segregate it approximately symmetrically, by the insertion of ParM subunits at either end

  7. Distinctive G Protein-Dependent Signaling by Protease-Activated Receptor 2 (PAR2 in Smooth Muscle: Feedback Inhibition of RhoA by cAMP-Independent PKA.

    Directory of Open Access Journals (Sweden)

    Wimolpak Sriwai

    Full Text Available We examined expression of protease-activated receptors 2 (PAR2 and characterized their signaling pathways in rabbit gastric muscle cells. The PAR2 activating peptide SLIGRL (PAR2-AP stimulated Gq, G13, Gi1, PI hydrolysis, and Rho kinase activity, and inhibited cAMP formation. Stimulation of PI hydrolysis was partly inhibited in cells expressing PAR2 siRNA, Gaq or Gai minigene and in cells treated with pertussis toxin, and augmented by expression of dominant negative regulator of G protein signaling (RGS4(N88S. Stimulation of Rho kinase activity was abolished by PAR-2 or Ga13 siRNA, and by Ga13 minigene. PAR2-AP induced a biphasic contraction; initial contraction was selectively blocked by the inhibitor of PI hydrolysis (U73122 or MLC kinase (ML-9, whereas sustained contraction was selectively blocked by the Rho kinase inhibitor (Y27632. PAR2-AP induced phosphorylation of MLC20, MYPT1 but not CPI-17. PAR2-AP also caused a decrease in the association of NF-kB and PKA catalytic subunit: the effect of PAR2-AP was blocked by PAR2 siRNA or phosphorylation-deficient RhoA (RhoA(S188A. PAR2-AP-induced degradation of IkBa and activation of NF-kB were abolished by the blockade of RhoA activity by Clostridium botulinum C3 exoenzyme suggesting RhoA-dependent activation of NF-kB. PAR2-AP-stimulated Rho kinase activity was significantly augmented by the inhibitors of PKA (myristoylated PKI, IKK2 (IKKIV or NF-kB (MG132, and in cells expressing dominant negative mutants of IKK (IKK(K44A, IkBa (IkBa (S32A/S36A or RhoA(S188A, suggesting feedback inhibition of Rho kinase activity via PKA derived from NF-kB pathway. PAR2-AP induced phosphorylation of RhoA and the phosphorylation was attenuated in cells expressing phosphorylation-deficient RhoA(S188A. Our results identified signaling pathways activated by PAR2 to mediate smooth muscle contraction and a novel pathway for feedback inhibition of PAR2-stimulated RhoA. The pathway involves activation of the NF-kB to

  8. uPAR as anti-cancer target

    DEFF Research Database (Denmark)

    Lund, Ida K; Illemann, Martin; Thurison, Tine

    2011-01-01

    , and a potential diagnostic and predictive impact of the different uPAR forms has been reported. Hence, pericellular proteolysis seems to be a suitable target for anti-cancer therapy and numerous approaches have been pursued. Targeting of this process may be achieved by preventing the binding of uPA to u...... using mouse monoclonal antibodies (mAbs) against mouse uPA or uPAR. These reagents will target uPA and uPAR in both stromal cells and cancer cells, and their therapeutic potential can now be assessed in syngenic mouse cancer models....

  9. Protection des ions organiques contre les dommages induits a l'ADN par les electrons de basse energie

    Science.gov (United States)

    Dumont, Ariane

    Il a ete demontre que les electrons de basse energie (EBE) peuvent induire des cassures simple brin (CSB) a l'ADN, via la formation d'anions transitoires qui decroissent par attachement dissociatif, ou dans d'autres etats electroniques dissociatifs menant a la fragmentation. Afin d'effectuer une etude complete des effets des electrons de basse energie sur la matiere biologique, il est necessaire de comprendre leur mecanismes d'interaction non seulement avec l'ADN, mais avec les constituants de son environnement. Les histones sont une composante importante de l'environnement moleculaire de l'ADN. Leur charge positive leur permet de s'associer aux groupements phosphate anionique de l'ADN. Le role principal de ces proteines basiques consiste a organiser l'ADN et l'empaqueter afin de former la chromatine. Les cations sont une autre composante importante de la cellule; ils jouent un role dans la stabilisation de la conformation B de l'ADN in vitro par leurs interactions avec les petits et grands sillons de l'ADN, ainsi qu'avec le groupement phosphate charge negativement. Avec les histones, ils participent egalement a la compaction de l'ADN pour former la chromatine. Cette etude a pour but de comprendre comment la presence d'ions organiques (sous forme de Tris et d'EDTA) a proximite de l'ADN modifie le rendement de cassures simple brin induit par les electrons de basse energie. Le Tris et l'EDTA ont-ete choisis comme objet d'etude, puisqu'en solution, ils forment le tampon standard pour solubiliser l'ADN dans les experiences in vitro (10mM Tris, 1mM EDTA). De plus, la molecule Tris possede un groupement amine alors que l'EDTA possede 4 groupements carboxyliques. Ensembles, ils peuvent se comporter comme un modele simple pour les acides amines. Le ratio molaire de 10 :1 de Tris par rapport a l'EDTA a pour but d'imiter le comportement des histones qui sont riches en arginine et lysine, acides amines possedant un groupement amine charge positivement additionnel. Des films d

  10. Détermination de la contamination par l'Aflatoxine B1 de la pâte d ...

    African Journals Online (AJOL)

    de déterminer par CCM si les niveaux de contamination naturelle par l'AFB1 des pâtes d'arachide vendues sur les marchés d'Abidjan étaient supérieurs aux limites maximales de résidus autorisées. ... l'Hépatite C, le risque de développer un cancer du foie est extrêmement élevé lorsqu'ils sont exposés aux Aflatoxines.

  11. Protease-activated receptor (PAR2, but not PAR1, is involved in collateral formation and anti-inflammatory monocyte polarization in a mouse hind limb ischemia model.

    Directory of Open Access Journals (Sweden)

    Lisa G van den Hengel

    Full Text Available AIMS: In collateral development (i.e. arteriogenesis, mononuclear cells are important and exist as a heterogeneous population consisting of pro-inflammatory and anti-inflammatory/repair-associated cells. Protease-activated receptor (PAR1 and PAR2 are G-protein-coupled receptors that are both expressed by mononuclear cells and are involved in pro-inflammatory reactions, while PAR2 also plays a role in repair-associated responses. Here, we investigated the physiological role of PAR1 and PAR2 in arteriogenesis in a murine hind limb ischemia model. METHODS AND RESULTS: PAR1-deficient (PAR1-/-, PAR2-deficient (PAR2-/- and wild-type (WT mice underwent femoral artery ligation. Laser Doppler measurements revealed reduced post-ischemic blood flow recovery in PAR2-/- hind limbs when compared to WT, while PAR1-/- mice were not affected. Upon ischemia, reduced numbers of smooth muscle actin (SMA-positive collaterals and CD31-positive capillaries were found in PAR2-/- mice when compared to WT mice, whereas these parameters in PAR1-/- mice did not differ from WT mice. The pool of circulating repair-associated (Ly6C-low monocytes and the number of repair-associated (CD206-positive macrophages surrounding collaterals in the hind limbs were increased in WT and PAR1-/- mice, but unaffected in PAR2-/- mice. The number of repair-associated macrophages in PAR2-/- hind limbs correlated with CD11b- and CD115-expression on the circulating monocytes in these animals, suggesting that monocyte extravasation and M-CSF-dependent differentiation into repair-associated cells are hampered. CONCLUSION: PAR2, but not PAR1, is involved in arteriogenesis and promotes the repair-associated response in ischemic tissues. Therefore, PAR2 potentially forms a new pro-arteriogenic target in coronary artery disease (CAD patients.

  12. Searching for reflected light from τ Bootis b with high-resolution ground-based spectroscopy: Approaching the 10-5 contrast barrier

    Science.gov (United States)

    Hoeijmakers, H. J.; Snellen, I. A. G.; van Terwisga, S. E.

    2018-02-01

    Context. It is challenging to measure the starlight reflected from exoplanets because of the extreme contrast with their host stars. For hot Jupiters, this contrast is in the range of 10-6 to 10-4, depending on their albedo, radius and orbital distance. Searches for reflected light have been performed since the first hot Jupiters were discovered, but with very limited success because hot Jupiters tend to have low albedo values due to the general absence of reflective cloud decks. Aim. The aim of this study is to search for reflected light from τ Boo b, a hot Jupiter with one of the brightest host stars. Since its discovery in 1997, it has been the subject of several reflected-light searches using high-dispersion spectroscopy. Here we aim to combine these data in to a single meta-analysis. Methods: We analysed more than 2000 archival high-dispersion spectra obtained with the UVES, ESPaDOnS, NARVAL UES and HARPS-N spectrographs during various epochs between 1998 and 2013. Each spectrum was first cleaned of the stellar spectrum and subsequently cross-correlated with a PHOENIX model spectrum. These were then Doppler shifted to the planet rest-frame and co-added in time, weighted according to the expected signal-to-noise of the planet signal. Results: We reach a 3σ upper limit of the planet-to-star contrast of 1.5 × 10-5. Assuming a planet radius of 1.15 RJ, this corresponds to an optical albedo of between 400-700 nm. A low albedo is in line with secondary eclipse and phase curve observations of other hot Jupiters using space-based observatories, as well as theoretical predictions of their reflective properties.

  13. Copenhagen uPAR prostate cancer (CuPCa) database

    DEFF Research Database (Denmark)

    Lippert, Solvej; Berg, Kasper D; Høyer-Hansen, Gunilla

    2016-01-01

    AIM: Urokinase plasminogen activator receptor (uPAR) plays a central role during cancer invasion by facilitating pericellular proteolysis. We initiated the prospective 'Copenhagen uPAR Prostate Cancer' study to investigate the significance of uPAR levels in prostate cancer (PCa) patients. METHODS...

  14. Poder académico versus autoridad femenina: la Facultad de Medicina de París contra Jacoba Félicié ( 1322 )

    OpenAIRE

    Cabré Pairet, Montserrat; Salmón Muñiz, Fernando

    1999-01-01

    Este artículo analiza el juicio que la Facultad de Medicina de París incoó contra Jacoba Félicié en 1322. Partiendo de las narrativas de sus pacientes, intenta interpretar la práctica médica de Jacoba y la naturaleza específica de la relación establecida con sus pacientes. Para identificar y describir esta relación, utilizamos una distinción básica entre poder y autoridad.

  15. Recombination in the human Pseudoautosomal region PAR1.

    Directory of Open Access Journals (Sweden)

    Anjali G Hinch

    2014-07-01

    Full Text Available The pseudoautosomal region (PAR is a short region of homology between the mammalian X and Y chromosomes, which has undergone rapid evolution. A crossover in the PAR is essential for the proper disjunction of X and Y chromosomes in male meiosis, and PAR deletion results in male sterility. This leads the human PAR with the obligatory crossover, PAR1, to having an exceptionally high male crossover rate, which is 17-fold higher than the genome-wide average. However, the mechanism by which this obligatory crossover occurs remains unknown, as does the fine-scale positioning of crossovers across this region. Recent research in mice has suggested that crossovers in PAR may be mediated independently of the protein PRDM9, which localises virtually all crossovers in the autosomes. To investigate recombination in this region, we construct the most fine-scale genetic map containing directly observed crossovers to date using African-American pedigrees. We leverage recombination rates inferred from the breakdown of linkage disequilibrium in human populations and investigate the signatures of DNA evolution due to recombination. Further, we identify direct PRDM9 binding sites using ChIP-seq in human cells. Using these independent lines of evidence, we show that, in contrast with mouse, PRDM9 does localise peaks of recombination in the human PAR1. We find that recombination is a far more rapid and intense driver of sequence evolution in PAR1 than it is on the autosomes. We also show that PAR1 hotspot activities differ significantly among human populations. Finally, we find evidence that PAR1 hotspot positions have changed between human and chimpanzee, with no evidence of sharing among the hottest hotspots. We anticipate that the genetic maps built and validated in this work will aid research on this vital and fascinating region of the genome.

  16. Association entre le travail par quarts et l’obésité chez les hommes dans le nord-est de l’Ontario

    Directory of Open Access Journals (Sweden)

    Anne Grundy

    2017-01-01

    Full Text Available Introduction : Même si certaines études suggèrent une association entre le travail par quarts et l’obésité, peu sont fondées sur la population ou tiennent compte de divers horaires de travail par quarts. L’obésité étant associée à plusieurs problèmes de santé chroniques, il est important de comprendre quelles formes de travail par quarts ont une incidence sur elle et d’effectuer des travaux permettant d’évaluer de façon plus détaillée l’exposition au travail par quarts. Méthodologie : Au moyen d’une régression logistique polytomique multivariée, nous avons étudié l’association entre le travail par quarts (de soir ou nuit, par quarts ou autre type de rotation et le surpoids et l’obésité, en fonction d’une mesure transversale de l’indice de masse corporelle chez 1 561 hommes. Ces hommes avaient déjà servi de témoins dans une étude cas-témoins sur le cancer de la prostate menée dans le nord-est de l’Ontario de 1995 à 1999. Nous avons obtenu l’information sur leurs antécédents de travail (notamment sur le travail par quarts, leur taille et leur poids à partir de données autodéclarées recueillies par questionnaire. Résultats : Nous avons observé une association entre le fait d’avoir déjà travaillé par quarts (par opposition au fait de n’avoir jamais travaillé par quarts et le surpoids (RC [rapport de cotes] = 1,34; IC [intervalle de confiance] à 95 % : 1,05 à 1,73 ainsi que l’obésité (RC = 1,57; IC à 95 % : 1,12 à 2,21. Nous avons également observé des associations statistiquement non significatives avec le fait d’avoir déjà travaillé (par opposition au fait de n’avoir jamais travaillé de façon permanente selon un quart de soir ou de nuit. Nous avons par ailleurs observé une tendance à la hausse statistiquement significative en ce qui concerne le risque de surpoids et d’obésité en fonction de la durée du travail par quarts. Conclusion : Tant l

  17. Plasma suPAR is lowered by smoking cessation

    DEFF Research Database (Denmark)

    Eugen-Olsen, Jesper; Ladelund, Steen; Sørensen, Lars Tue

    2016-01-01

    BACKGROUND: Soluble urokinase plasminogen activator receptor (suPAR) is a stable inflammatory biomarker. In patients, suPAR is a marker of disease presence, severity and prognosis. In the general population, suPAR is predictive of disease development, such as diabetes and cardiovascular disease a...

  18. 24 CFR 901.105 - Computing assessment score.

    Science.gov (United States)

    2010-04-01

    ... development) has at least 51% of families with incomes below the poverty rate as documented by the latest... surrounding the development(s) in question with supporting census data showing the level of poverty. Units... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Computing assessment score. 901.105...

  19. Tank 241-TX-105 tank characterization plan

    International Nuclear Information System (INIS)

    Carpenter, B.C.

    1995-01-01

    This document is a plan which serves as the contractual agreement between the Characterization Program, Sampling Operations, WHC 222-S Laboratory, Oak Ridge National Laboratory, and PNL tank vapor program. The scope of this plan is to provide guidance for the sampling and analysis of vapor samples from tank 241-TX-105

  20. Cleanup Verification Package for the 118-B-1, 105-B Solid Waste Burial Ground

    International Nuclear Information System (INIS)

    Capron, J.M.

    2008-01-01

    This cleanup verification package documents completion of remedial action, sampling activities, and compliance criteria for the 118-B-1, 105-B Solid Waste Burial Ground. This waste site was the primary burial ground for general wastes from the operation of the 105-B Reactor and P-10 Tritium Separation Project and also received waste from the 105-N Reactor. The burial ground received reactor hardware, process piping and tubing, fuel spacers, glassware, electrical components, tritium process wastes, soft wastes and other miscellaneous debris

  1. Nuevas técnicas de construcción del metropolitano de París - Francia

    Directory of Open Access Journals (Sweden)

    Vié, G.

    1972-02-01

    Full Text Available The transport of the Paris population within the city is becoming so difficult that a new organisation has taken up the enlargement of the current underground network. Technological advances in tunnel engineering are such that the construction of tunnels and stations is now possible under conditions which would have been impossible in earlier decades. In this article the project requirements and the adopted solutions are described in some detail.Los problemas de desplazamiento y transporte de los habitantes de París son tan acuciantes que una nueva empresa se ha lanzado a ampliar la red metropolitana. El progreso de la técnica ha permitido que la construcción de túneles y estaciones se resuelva en condiciones que hubieran sido inabordables cuando se construyó la red inicial. En el artículo se describen las necesidades a resolver y las soluciones adoptadas.

  2. Parcerias institucionais e evolução do extrativismo de jaborandi na Floresta Nacional de Carajás, Pará, Brasil

    Directory of Open Access Journals (Sweden)

    Fabiano Gumier-Costa

    2016-12-01

    Full Text Available Este artigo discute o extrativismo vegetal na região Amazônica a partir da coleta extrativa de folhas de jaborandi, na região de Carajás (Pará, Brasil. Esta planta é utilizada para a extração de pilocarpina que é o insumo para a produção de colírios para tratamento de glaucoma. Buscou-se analisar e teorizar sobre os complexos e múltiplos fatores que determinam a substituição, ou não, da atividade extrativista. A estabilização da demanda nacional e internacional por pilocarpina está permitindo a coexistência do dualismo tecnológico do cultivo da planta e o processo extrativista. Também fica evidente a estratégia por parte de uma das empresas que lideram a extração e exportação de pilocarpina em agregar uma imagem positiva decorrente das parcerias com comunidades extrativistas no Pará e outras regiões de ocorrência natural do jaborandi.

  3. Contribuição dos parâmetros biomecânicos para o desempenho de saltos verticais de jogadoras de basquetebol Contribución de los parámetros biomecánicos para el desempeño en saltos verticales de jugadoras de baloncesto Contribution of biomechanical parameters to vertical jump performance in basketball players

    Directory of Open Access Journals (Sweden)

    Rodrigo Maciel Andrade

    2012-06-01

    Full Text Available O objetivo do presente estudo foi investigar a contribuição dos parâmetros biomecânicos para o desempenho do salto vertical com contramovimento (SV e SV precedido de corrida (SVcorrida em 19 jogadoras da seleção brasileira adulta de basquetebol feminino (26,2 ± 4,7 anos; 1,81 ± 0,07 m; 75,6 ± 12,6 kg; 20,4 ± 6,0% de gordura. Foram considerados os picos de força passiva (PFPa e propulsão (PFP, tempo para alcance dos picos de força passiva (TPFPa e propulsão (TPFP, "load rate" (LR, taxa de desenvolvimento de força (TDF, tempo de fase excêntrica (Texc e concêntrica (Tcon. A análise de componentes principais revelou que 50,86% da altura de SV foi explicada por PFPa, TPFPa, LR, Texc e TPFP, e que 43,28% de SVcorrida foi explicada por PFPa, TPFPa, LR, PFP. Esses resultados sugerem que parâmetros temporais parecem contribuir de maneira mais significativa para o desempenho de salto, porém diferentes tipos de salto podem demandar comportamentos distintos de parâmetros biomecânicos.El objetivo de este estudio fue investigar la contribución de parámetros biomecánicos para el rendimiento de salto vertical con contra movimiento (SV e SV precedido de carrera (SVcarrera en diecinueve jugadoras de baloncesto de la selección brasileña femenina adultas (26,2 ± 4,7 años; 1,81 ± 0,07 m; 75,6 ± 12,6 kg; 20,4 ± 6,0% de grasa. Fueran considerados el pico de fuerza pasiva (PFPa y propulsión (PFP, tiempo para llegar a picos de fuerza pasiva (TPFPa y propulsión (TPFP, la tasa de carga (LR, tasa de desarrollo de fuerza (TDF, tiempo de la fase excéntrica (Texc y concéntrica (Tcon. Las análisis de los componentes principales mostraron que 50,86% da la altura de SV fue explicada por PFPa, TPFPa, LR, Texc y TPFP, y que 43,28% de SVcarrera fue explicada por PFPa, TPFPa, LR, PFP. Los resultados sugieren parámetros temporales parecen contribuir más significativamente para rendimiento del salto pero, diferentes tipos del salto pueden

  4. 46 CFR 105.05-1 - Commercial fishing vessels dispensing petroleum products.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Commercial fishing vessels dispensing petroleum products... MISCELLANEOUS VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Application § 105.05-1 Commercial fishing vessels dispensing petroleum products. (a) The provisions of this part, with the exception of...

  5. 15 CFR 2011.105 - Form and applicability of certificate.

    Science.gov (United States)

    2010-01-01

    ..., SYRUPS AND MOLASSES Certificate of Quota Eligibility § 2011.105 Form and applicability of certificate. (a...; expected date of departure; expected date of arrival in U.S.; and expected port(s) of arrival in the United... shall affix a seal or other form of authentication and sign and date the certificate. (b) Other...

  6. Ammonia Liberation from PRL at Alkaline pH

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. The k value was calculated as 4.07 x 10-5 sec-1. The k value was calculated as 4.07 x 10-5 sec-1. One mole prolactin can libebrate 1.29 nmol of NH3 within 36hr of incubation at 37oC.

  7. Equações de chuvas intensas para o estado do Pará Intense rainfall equations for the state of Pará, Brazil

    Directory of Open Access Journals (Sweden)

    Rodrigo O. R. de M. Souza

    2012-09-01

    Full Text Available As equações de chuvas intensas têm sido usadas como ferramenta importante para o dimensionamento de obras hidráulicas. Devido à grande carência de informações relativas às equações de chuvas intensas, o presente trabalho teve como objetivo a obtenção das relações de intensidade, duração e frequência de precipitação pluvial para o Estado do Pará, utilizando-se a metodologia da desagregação da chuva de 24 h. Foram utilizadas séries históricas de dados pluviométricos de 74 cidades do Estado do Pará, obtidas no Sistema de Informações Hidrológicas da Agência Nacional de Águas-ANA. As equações de intensidade-duração-frequência foram devidamente ajustadas e apresentaram bom ajuste, com coeficientes de determinação acima de 0,99. A maioria das estações (51,4% apresentou intensidade de precipitação entre 90 e 110 mm h-1, para uma duração de chuva de 30 min e um tempo de retorno de 15 anos. Pode-se perceber uma concentração das maiores precipitações na região próxima ao litoral do nordeste paraense e no sudeste da Ilha do Marajó.The intense rainfall equations have been used as an important tool for design of hydraulic structures. Considering the lack of intense rainfall equations, this study aimed to determine the relations of intensity, duration and frequency of intense rainfall in the Pará State (Brazil, using the one-day rain disaggregation method. In this research rainfall data of 74 cities in the State of Pará were used, obtained from the Hydrological Information System of the National Water Agency-ANA. The equations of intensity-duration-frequency were adjusted and presented good adjustment with coefficients of determination above 0.99. Most stations (51.4% showed intensity of precipitation between 90 and 110 mm h-1 for duration of 30 min and rainfall return period of 15 years. The highest rainfall intensities were in the region near the northeast coast of Pará State and southeast of the Marajo

  8. Repérer des sites similaires à une recherche par Google

    OpenAIRE

    Ginouvès, Véronique

    2006-01-01

    Repérer des sites similaires à une recherche par Google Afficher graphiquement les liens d’un site avec d’autres sites similaires TouchGraph GoogleBrowser crée des agrégations de sites à partir de l’interrogation de Google. Vous visualisez ainsi des nébuleuses de sites à l’intérieur desquelles vous pouvez naviguer facilement, en sautant d'un groupe à l'autre afin de voir les nuages autour de sujets ou de communautés de sujets. Cet outil a été développé par Alex Shapiro, à partir de la version...

  9. Las residencias de Carlos III el Noble en París a comienzos del siglo XV : el Hôtel de Clisson y el Hôtel de Navarre

    Directory of Open Access Journals (Sweden)

    María NARBONA CÁRCELES

    2009-05-01

    Full Text Available Uno de los temas que atañen a la itinerancia cortesana es el de la instalación en una gran ciudad. Y, entre las grandes capitales del momento, París se mostraba indiscutiblemente como lugar de paso o de destino privilegiado de muchos de estos príncipes «itinerantes». Carlos III el Noble, rey de Navarra (1387-1425, fue uno de los grandes príncipes foráneos que frecuentaron París, realizando allí durante largas estancias, entre 1378 y 1411, de las cuales se ha conservado una interesante documentación. La cuestión del alojamiento del rey de Navarra en París, a partir de los documentos conservados tanto en los archivos franceses como en los navarros, será el tema de este trabajo. Además, la reaparición de un «Hôtel de Navarre» en París en los últimos años del siglo XIV, se presenta como un claro síntoma de la presencia de nuevo de los Navarra-Évreux en el seno de la corte francesa.L’un des sujets concernant l’itinérance de la cour est celui de l’installation dans une grande ville. Et, parmi les grandes capitales du moment, Paris était, de façon indiscutable, le lieu de passage ou de destination privilégiée de beaucoup de ces princes « itinérants ». Charles III, le Noble, roi de Navarre (1387-1425, a été l’un de ces princes étrangers qui l’ont fréquentée, y demeurant pendant des longs séjours, entre 1378 et 1411, pour lesquels on conserve une intéressante documentation. La question abordée ici sera celle du logement du roi de Navarre à Paris, à partir des documents conservés autant dans des archives françaises que navarraises. De plus, la réapparition d’un « Hôtel de Navarre » à Paris dans les dernières années du XIVe siècle, est un clair symptôme de la présence, à nouveau, des Navarre-Évreux au sein de la cour de France.

  10. Magnetic resonance imaging in Parkinson's disease; The evaluation of the width of pars compacta on T2 weighted image

    Energy Technology Data Exchange (ETDEWEB)

    Moriwaka, Fumio; Tashiro, Kunio; Itoh, Kazunori; Miyasaka, Kazuo [Hokkaido Univ., Sapporo (Japan). School of Medicine; Hamada, Takeshi

    1992-01-01

    The width of substantia nigra (SN) in 59 cases of idiopathic Parkinson's disease as well as 21 normal controls was analyzed by T2 weighted image (T2WI) of 1.5 Tesla high-field magnetic resonance image (MRI). All patients and controls underwent MRI with the spin-echo sequences used TR/TE: 3000/30 (short TE), and TR/TE: 3000/80 (long TE), in 5-mm-thick volumes. The width between the red nucleus and the cerebral peduncle showing low signal intensity areas was measured as that of SN and its ratio to the distance from the aqueduct to the midline of the cerebral peduncle was also measured. The calculated values of the width of SN and its ratio were analyzed by Mann-Whitney test. The significant reduction in the width of SN and its ratio in Parkinson's disease were disclosed below: the mean calculated values of the width of SN were 2.95{+-}0.51 mm in controls, 2.68{+-}0.99 mm in Parkinson's disase on long TE images (P<0.01), and the mean ratio of the width of SN were 13.58{+-}4.21% in controls, 10.52{+-}3.07% in Parkinson's disease on long TE images (P=0.0002). The narrowing of SN in Parkinson's disease was more prominent in men, and advanced cases with Yahr stage III and IV. Considering that the pars reticulata, which is normally containing iron, shows low signal intensity on long TE images, the width of pars compacta could be measured more precisely on this sequences. The evaluation of the ratio of SN in midbrain on long TE images seemed to be more sensitive than the calculated values in detecting the narrowing of SN and pars compacta in Parkinson's disease. (author).

  11. Plasma suPAR levels are associated with mortality, admission time, and Charlson Comorbidity Index in the acutely admitted medical patient

    DEFF Research Database (Denmark)

    Haupt, Thomas Huneck; Petersen, Janne; Ellekilde, Gertrude

    2012-01-01

    . METHODS: We included 543 patients with various diseases from a Danish Acute Medical Unit during a two month period. A triage unit ensured that only medical patients were admitted to the Acute Medical Unit. SuPAR was measured on plasma samples drawn upon admission. Patients were followed-up for three......, and it is speculated that suPAR is a low-grade inflammation marker reflecting on disease severity. The aim of this prospective observational study was to determine if the plasma concentration of suPAR is associated with admission time, re-admission, disease severity/Charlson Comorbidity Index Score, and mortality...... months after inclusion by their unique civil registry number and using Danish registries to determine admission times, readmissions, International Classification of Diseases, 10th Edition (ICD-10) diagnoses, and mortality. Statistical analysis was used to determine suPAR's association...

  12. MODELISATION DE LA CINETIQUE CHIMIQUE DANS LA REDUCTION DES OXYDES D4AZOTE PAR DECHARGE COURONNE.

    OpenAIRE

    MEDJAHDI, Sarah ines

    2015-01-01

    CE TRAVAIL DE recherche rentre dans le cadre général de modélisation de la réduction des oxydes d'azote . l'utilisation des réacteurs a plasma froid non-thermique généré par des décharges couronnes est actuellement l'une des techniques les puis promettre .ses pour la destruction des oxydes d'azote .en effet , le traitement des gaz pollués par les décharges couronnes est notamment rendu possible par la multiplication des décharges Électriques .

  13. The inflammatory marker suPAR after cardiac arrest

    DEFF Research Database (Denmark)

    Rundgren, Malin; Lyngbaek, Stig; Fisker, Helle

    2015-01-01

    . This pilot study aimed at investigating suPAR levels in relation to outcome after CA and mild induced hypothermia. METHODS: suPAR levels were measured at 6, 36, and 72 hours in patients treated with hypothermia after CA. suPAR levels were analyzed in relation to survival after 6 months. Receiver operating...

  14. Insectos parásitos que afectan a loros de Argentina y métodos para su obtención

    OpenAIRE

    Aramburú, Rosana

    2012-01-01

    Las aves son parasitadas por una comunidad diversa de artrópodos, que pueden ser la causa principal de morbilidad y mortalidad en pichones y adultos. En este trabajo se brinda información sobre métodos para obtener insectos parásitos, distinguiendo métodos sobre el ave (para parásitos permanentes) y de búsqueda en el nido (para parásitos temporarios). Se ofrecen comentarios sobre algunos de los grupos más importantes de insectos parásitos de loros que se distribuyen en Argentina: piojos masti...

  15. Linear chrono-amperometry using re-dissolution: application to halides; La chronoamperometrie lineaire par redissolution: application aux halogenures

    Energy Technology Data Exchange (ETDEWEB)

    Perchard, J -P; Buvet, M; Molina, R [Commissariat a l' Energie Atomique, Centre d' Etudes Nucleaires de Fontenay-aux-Roses, 92 (France)

    1966-06-01

    The possibility of applying linear chrono-amperometry to analysis was studied using a falling-drop mercury electrode. Measurements of the cations were carried out by direct reduction or by prior formation of an amalgam, which is then oxidized. Using the first technique, the minimum concentration that can be attained is about 10{sup -6} M and the reproducibility of the results is of the order of 2%. With the second method the sensitivity is much improved: in the concentration range of 10{sup -7} to 10{sup -8} M, the scatter of the results is less than 10% if the agitation and temperature conditions are kept constant. The halides are determined by re-dissolving the mercurous halide deposit formed by electrolysis. From the analytical point of view, the sensitivity is limited in the domain where the phenomena can be interpreted and used. In the case of the chloride ion the lower limit of this zone is close to 10{sup -5} M; it is 10{sup -6} M for the bromide and less than 10{sup -7} M for the iodide. For lower concentrations, simple laws that might be applied in analysis are no longer valid. However, the splitting of the peak observed during the reduction of the mercurous iodide deposit was interpreted as showing that the mono-molecular Hg{sub 2}I{sub 2} layer formed on the drop has particular electrochemical properties. (authors) [French] Les possibilites analytiques de la chronoamperometrie lineaire ont ete etudiees en utilisant une electrode de mercure a goutte pendante. Le dosage des cations a ete effectue par reduction directe ou par formation prealable d'un amalgame puis oxydation de celui-ci. Par la premiere technique la concentration minimale que l'on peut atteindre est d'environ 10{sup -6} M et la reproductibilite des resultats est de l'ordre de 2%. Par la seconde methode la sensibilite se trouve grandement amelioree; dans une zone de concentration comprise entre 10{sup -7} et 10{sup -8} M, la dispersion des determinations est inferieure a 10% si les conditions

  16. Aplicación de técnicas sísmicas como herramienta para la obtención de parámetros geomecánicos del terreno en la urbanización Camposol, Mazarrón

    OpenAIRE

    Morales Giménez, Pedro

    2015-01-01

    Para el cálculo de parámetros geomecánicos del terreno, pueden ser empleados los valores de las velocidades de ondas compresionales (P) y ondas de cizalla (S) mediante métodos geofísicos superficiales. Estos parámetros son fundamentales para obtener las características de las zonas en las que se procede a la realización de obras civiles, edificios, etc. Y a la minimización del riesgo sísmico en las mismas, así como de asentamientos incontrolados del terreno, estabilidad de t...

  17. 46 CFR 105.90-1 - Existing commercial fishing vessels dispensing petroleum products.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Existing commercial fishing vessels dispensing petroleum... AND MISCELLANEOUS VESSELS COMMERCIAL FISHING VESSELS DISPENSING PETROLEUM PRODUCTS Existing Commercial Fishing Vessels Dispensing Petroleum Products § 105.90-1 Existing commercial fishing vessels dispensing...

  18. Results of Preliminary Tests of PAR Bunch Cleaning

    CERN Document Server

    Yao, Chihyuan; Grelick, Arthur; Lumpkin, Alex H; Sereno, Nicholas S

    2005-01-01

    A particle accumulator ring (PAR) is used at the Advanced Photon Source (APS) to collect multiple linac bunches and compress them into a 0.3-ns (rms) single bunch for booster injection. A 9.77-MHz fundamental rf system and a 117.3-MHz harmonic rf system are employed for initial beam capture and bunch length compression. Satellite bunches with very low charge form due to rf phase drifts or beam loading change. These satellites, when injected into the booster and then into the storage ring (SR), cause bunch impurity at three buckets from the target bucket. Storage ring and booster bunch cleaning was tried but proved to be difficult due to the top-up mode of operation in the storage ring and tune drift in the booster synchrotron. Recently we implemented a PAR bunch-cleaning system with tune-modulated harmonic rf knockout. Preliminary tests gave a measured SR bunch purity of better than 10

  19. 21 CFR 201.105 - Veterinary drugs.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Veterinary drugs. 201.105 Section 201.105 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL LABELING Exemptions From Adequate Directions for Use § 201.105 Veterinary drugs. A drug subject to the...

  20. 7 CFR 1942.105 - Environmental review.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 13 2010-01-01 2009-01-01 true Environmental review. 1942.105 Section 1942.105... § 1942.105 Environmental review. FmHA or its successor agency under Public Law 103-354 must conduct and document an environmental review for each proposed project in accordance with subpart G of part 1940 of...