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Sample records for royal adelaide hospital

  1. Radiotherapy alone for early stage Hodgkin's disease: a 16 year experience at the Royal Adelaide Hospital

    International Nuclear Information System (INIS)

    O'Brein, P.

    1994-01-01

    The records of all patients with stage I and II Hodgkin's disease treated with radiotherapy alone at the Royal Adelaide Hospital between 1970 and 1986 were reviewed. The aim was to ensure the results were equivalent to the best reported series, particularly as treating such patients with chemotherapy alone has been shown to produce equivalent overall survival figures with improved relapse-free survival. There were 104 patients of whom 67 and undergone staging laparotomy. Fifty-seven patients were stage I and 47 stage II. Nine patients had B symptoms. Overall survival at 10 years was 83% with disease-specific survival being 86% and relapse-free survival 68%. These results compare favourably with those in the world literature. Multivariate analysis only revealed stage as an independent predictor of improved relapse-free survival. 30 refs., 3 figs., 3 tabs

  2. Radiosurgery for brain metastases at the Royal Adelaide Hospital: are we treating the right patients?

    International Nuclear Information System (INIS)

    Roos, D.E.; Brophy, B.P.; Zavgorodni, S.F.; Katsilis, E.S.

    2002-01-01

    Although non-randomized data strongly suggest improved outcome from radiosurgery (RS) for brain metastases relative to whole brain radiotherapy (WBRT) alone, selection factors account for much of the observed differences. This retrospective review of the 16 brain metastases patients treated so far with RS at the Royal Adelaide Hospital confirms a median survival of 10.1 months, consistent with recent multi-institutional pooled results and significantly longer than the median survival of 3-6 months typically reported for WBRT alone. The emerging randomized trials comparing surgery, RS and WBRT for brain metastases are reviewed in the context of the Radiation Therapy Oncology Group Recursive Partitioning Analysis prognostic Class concept in order to assess whether we are using this resource intensive technique to treat the 'right' patients. We conclude that it is reasonable to continue our current policy of considering RS primarily for patients of good performance status with solitary brain metastases. VVe have a flexible approach to adjuvant WBRT which appears to decrease brain relapse, but not improve survival. Copyright (2002) Blackwell Science Pty Ltd

  3. Newborn transport in South Australia, 1978-80: experience of the Queen Victoria Hospital, Adelaide.

    Science.gov (United States)

    Davies, A G; Fitzgerald, A M; Dahlenburg, G W

    1982-01-23

    389 infants were transported to the Queen Victoria Hospital, Adelaide between 1978 and 1980. Twenty-three percent (99) of the infants were ventilated, and 49% (189) received intravenous or intra-arterial therapy. Fifty-six percent (217) of the infants required transport because of prematurity; 11% (46) because of perinatal asphyxia in babies weighing more than 2,500 g. Only one baby died during transport, while 14% of the babies died subsequently. A core temperature of less than 36 degrees C in either hospital is important; a cold baby is 3.5 times more likely to die (X2=25.46, P less than 0.001). The transport of babies over distances greater than 300 kilometres is peculiar to Australia. Significantly more of these babies were cold than those retrieved from hospitals near Adelaide (X2=4.7, P less than 0.05), and significantly more died. Difficulty in transferring mothers in preterm labour may be another reason these babies did relatively badly. Better education and facilities will be important if we are to improve their survival chances.

  4. Early examples of art in Scottish hospitals, 2: Crichton Royal Hospital, Dumfries.

    Science.gov (United States)

    Park, Maureen

    2003-12-01

    Fine art has been used in hospitals for centuries. However, Crichton Royal Hospital in Dumfries pioneered the use of art activity in the treatment of its patients. This article is the second of two which look at examples of art created for, and in, Scottish hospitals in the 19th century. It is suggested that the importance of Scotland's contribution to this movement is unrecognized by many of its modern-day practitioners.

  5. Round one of the Adelaide and Meath Hospital/Trinity College Colorectal Cancer Screening Programme: programme report and analysis based on established international key performance indices.

    LENUS (Irish Health Repository)

    McNamara, D

    2012-02-01

    BACKGROUND: In Ireland, colorectal cancer (CRC) is the second most frequently diagnosed cancer in men, after prostate cancer, and the second most frequently diagnosed cancer in women, after breast cancer. By 2020, the number of new cases diagnosed annually in Ireland is projected to have increased by 79% in men and 56% in women. Organised screening for CRC is already underway or is in the process of being rolled out in several European countries, either at a regional or national level. The Adelaide and Meath Hospital\\/ Trinity College Dublin Colorectal Cancer Screening Programme (TTC-CRC-SP) is Ireland\\'s first pilot population based bowel screening programme. METHOD: Based on a biennial test model the pilot aimed to assess the accuracy of FIT and to evaluate the whole programme based on established international key performance indices. RESULTS: To date 9,993 individuals aged 50-74 years have been invited to participate in the TTC-CRC-SP with over 5,000 FIT\\'s analysed. Overall uptake was 51% and FIT positivity was 10%. The programme has undertaken over 400 screening colonoscopies and detected 154 precancerous adenomas and 38 cancerous lesions. CONCLUSIONS: The first round of The Adelaide and Meath Hospital Tallaght\\/Trinity College Dublin Colorectal Cancer Screening Programme has been highly successful and confirmed that there is an advantage for FIT based two stage bowel cancer screening programmes.

  6. Royal london hospital set P28 plans 30th anniversary reunion.

    Science.gov (United States)

    Sibthorpe, Fran

    2013-04-03

    Members of Set P28 at the Royal London Hospital who began their training in February 1980 are planning a reunion on July 27 in London. The venue will be announced later. Email fran-joy@hotmail.com for details.

  7. Private finance initiative hospital architecture: towards a political economy of the Royal Liverpool University Hospital.

    Science.gov (United States)

    Jones, Paul

    2018-02-01

    Sociological analysis has done much to illuminate the architectural contexts in which social life takes place. Research on care environments suggests that the built environment should not be understood as a passive backdrop to healthcare, but rather that care is conditioned by the architecture in which it happens. This article argues for the importance of going beyond the hospital walls to include the politics that underwrite the design and construction of hospital buildings. The article assesses the case of the yet-to-be-realised Liverpool Royal University Hospital, and the private finance initiative (PFI) funding that underpins the scheme, which is suggested as a salient 'external' context for understanding architecture's role in the provision of healthcare of many kinds for many years to come. PFI has major implications for democratic accountability and local economy, as well as for the architecture of the hospital as a site of care. Critical studies can illuminate these paradoxically visible-but-opaque hospital spaces by going beyond that which is immediately empirically evident, so as to reveal the ways in which hospital architecture is conditioned by political and economic forces. © 2018 Foundation for the Sociology of Health & Illness.

  8. Fisher in Adelaide.

    Science.gov (United States)

    Mayo, Oliver

    2014-06-01

    R. A. Fisher spent much of his final 3 years of life in Adelaide. It was a congenial place to live and work, and he was much in demand as a speaker, in Australia and overseas. It was, however, a difficult time for him because of the sustained criticism of fiducial inference from the early 1950s onwards. The article discusses some of Fisher's work on inference from an Adelaide perspective. It also considers some of the successes arising from this time, in the statistics of field experimentation and in evolutionary genetics. A few personal recollections of Fisher as houseguest are provided. This article is the text of a article presented on August 31, 2012 at the 26th International Biometric Conference, Kobe, Japan. © 2014, The International Biometric Society.

  9. Total body irradiation and marrow transplantation for acute leukaemia. The Royal Marsden Hospital experience

    Energy Technology Data Exchange (ETDEWEB)

    Barrett, A; Barrett, A J; Powles, R L [Institute of Cancer Research, Sutton (UK). Surrey Branch; Royal Marsden Hospital, London (UK))

    1979-06-01

    The experience with total body irradiation at the Royal Marsden Hospital is described for an elective program of transplantation in patients with acute myeloid leukaemia (AML) in first remission. Dose rate appears to be a critical factor in the reduction of radiation-associated damage and careful monitoring of the actual dose distribution and dose received is mandatory.

  10. Two Years on: Koha 3.0 in Use at the CAMLIS Library, Royal London Homoeopathic Hospital

    Science.gov (United States)

    Bissels, Gerhard; Chandler, Andrea

    2010-01-01

    Purpose: The purpose of this paper is to describe the further development of the Koha 3.0 library management system (LMS) and the involvement of external software consultants at the Complementary and Alternative Medicine Library and Information Service (CAMLIS), Royal London Homoeopathic Hospital. Design/methodology/approach: The paper takes the…

  11. Tracheostomy decannulation at the Royal Hospital for Sick Children in Glasgow: Predictors of success and failure.

    Science.gov (United States)

    Beaton, Fiona; Baird, Tracy-Anne; Clement, W Andrew; Kubba, Haytham

    2016-11-01

    Tracheostomy techniques, indications and care are extensively covered in the literature. However, little is written about the process of removing the tracheostomy tube. At the Royal Hospital for Sick Children in Glasgow we use a stepwise ward-based protocol for safe tracheostomy decannulation. Our aim therefore was to review all the paediatric tracheostomy decannulations that we attempted over the last 3 years to evaluate our protocol, to determine our success rate and to see whether any modifications to the protocol are required. We reviewed all patients who had undergone ward decannulation between January 2012 and May 2015. We extracted data from clinical records including patient characteristics, indications for tracheostomy, timing of decannulation and success or failure of the process. The 45 children in the study underwent 57 attempts at decannulation during the study period. 25 were male (56%) and 20 were female (44%), and they were aged between 1 day and 16 years 6 months at the time of the original tracheostomy operation. 33 attempts were successful (58%). 10 children had more than one attempt at decannulation. Children were found to fail at every stage of the protocol, with the commonest point of failure being day 2 when the tracheostomy tube was capped. We have demonstrated that our current protocol for ward decannulation is effective and safe, and that all five days of the protocol are required. Crown Copyright © 2016. Published by Elsevier Ireland Ltd. All rights reserved.

  12. A portrait of prefrontal lobotomy performed at the Royal Prince Alfred Hospital in Sydney by Dr Rex Money.

    Science.gov (United States)

    White, Richard T; McGee-Collett, Martin

    2016-10-01

    The objective of this article is to provide a portrait of prefrontal lobotomy performed at the Royal Prince Alfred Hospital, Sydney by the Head of Neurosurgery Dr Rex Money and to describe Dr Money's role in the promotion of psychosurgery in Sydney. We draw attention to an oral presentation by Dr Rex Money in 1951, a journal article written by Money, archival information held at the Royal Prince Alfred Hospital, including Dr Money's accounts of his travels and his reports regarding neurosurgery - both internationally and in Australia. Dr Rex Money performed a series of 13 prefrontal lobotomies between 1945 and 1951, and presented the theoretical basis for his series, his operative procedures and the outcomes at the annual meeting of its medical officers' association. Notwithstanding various deficiencies in his clinical research, Money's descriptions give a relatively comprehensive account of one of the first series of prefrontal lobotomies performed in Australia. The current article also describes Dr Money's contributions to the promotion of psychosurgery in Sydney, and illustrates the participation of a senior neurosurgeon and of a major Sydney teaching hospital during the psychosurgery saga. © The Royal Australian and New Zealand College of Psychiatrists 2016.

  13. Our experience with the acceptance and dosimetric validation of Somatom Force dual head MDCT in the Royal Hospital, Oman

    International Nuclear Information System (INIS)

    Al-Harthi, Ruqaia; Al-Kalbani, Munira; Arun Kumar, L.S.; Al-Shanfari, Jamal

    2017-01-01

    Computed Tomography (CT) has revolutionized diagnostic imaging since its discovery in early 70's. In Oman; 70,353 CT examinations were carried out in the year 2015. The increase in CT examinations will eventually result in the increase of population dose and the consequent risk of cancer in adults and particularly in children. Here, we discuss and share our experience with the acceptance and dosimetric validation of second Dual Head Somatom Force MDCT installed in the Royal Hospital, Oman using Ministry of Health's radiation acceptance and quality assurance protocol, before handing over for routine patient care work

  14. Royal Victoria Eye and Ear Hospital annual report and accounts,1996: celebrating 100 years.

    LENUS (Irish Health Repository)

    1997-01-01

    The Dublin Eye and Ear Hospital Act, 1897 came in to force on 15th July 1897. The Act provided for the amalgamation of the National Eye and Ear Hospital in Molesworth Street (founded in 1814) and St Mark\\'s Ophthalmic Hospital in Lincoln Place founded in 1844 by Sir William R. Wilde) and established this Hospital. We are therefore celebrating this year the completion of one hundred year of service by the Hospital to the citizens of Dublin and indeed to people from all parts of Ireland.

  15. An evaluation of magnetic resonance imaging at the Royal North Shore Hospital of Sydney, 1986-1987

    International Nuclear Information System (INIS)

    Sorby, W.A.

    1989-01-01

    The diagnostic accuracy and clinical utility have been evaluated of 2810 consecutive magnetic-resonance-imaging examinations that were performed on a 1.5-T Signa magnetic-resonance-imaging unit at The Royal North Shore Hospital of Sydney between November 1986 and December 1987. The average accuracy of magnetic resonance imaging was 80%, and ranged from 21%-98% in various brain-disease and spinal-disease categories, compared with the average provisional premagnetic-resonance-imaging diagnostic accuracy of 64%, and an average accuracy of computed tomography of 45%. Clinical follow-up at three months after magnetic-resonance-imaging investigation indicated that, as a result of the magnetic-resonance-imaging examination, patient management was altered in 70% of cases, and patient outcome was altered in 62% of cases. 32 refs., 4 tabs

  16. Audit of referrals for concern regarding labial appearance at the Royal Children's Hospital: 2000-2012.

    Science.gov (United States)

    McQuillan, Sarah K; Jayasinghe, Yasmin; Grover, Sonia R

    2018-04-01

    To audit the clinical features and outcomes for all patients referred to our centre with concerns regarding labial appearance. Young females referred to a paediatric/adolescent gynaecology tertiary centre between 2000 and 2012 with concerns regarding their labial appearance were retrospectively identified. Adolescents presenting with anomalies were excluded. Retrospective chart review was undertaken to identify reasons for referral, patient characteristics, outcome of referral and concurrent health problems. In total, 46 females presenting with concerns about labial appearance were identified. Five were excluded. Median age of the study population was 14.5 years (range 5-21 years). Only four (9.8%) underwent surgery after a minimum of five consultations each, with mental health review in three of four cases prior to surgery. None of the 41 patients had documented abnormal labia; however, 6 patients had asymmetry, and 3 had a labial width of >5 cm. Of mothers, 24% (n = 10) raised the initial concern regarding labial appearance to a physician, of whom, 50% of patients had a comorbid condition. In total, 70.7% initially reported interference with daily activities, and 87.8% were reassured following discussion. With appropriate education and counselling, the majority of girls with concerns regarding labial appearance can be managed without surgery. Overall, our data support current international policy that female cosmetic genital surgery not be performed in mature minors unless there are specific indications. More research about characteristics of patients referred with labial concerns, definition of labial size and long-term satisfaction of conservative versus surgical methods is necessary to determine the best approach. © 2018 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).

  17. The future of hospital laboratories. Position statement from the Royal Belgian Society of Clinical Chemistry (RBSCC).

    Science.gov (United States)

    Langlois, Michel R; Wallemacq, Pierre

    2009-01-01

    To face the economic pressures arising from the current socio-economic conjuncture, hospital laboratories are endangered by an increasing trend towards the outsourcing of clinical laboratory tests to external (mega-) laboratories. This should allow hospitals to meet their economic requirements, but with an increased risk of loss of medical quality and, mid- to long-term, loss of cost effectiveness of healthcare at the national level. To anticipate current developments (economical and technological) that inevitably will affect the future of laboratory medicine, hospital laboratories should be proactive and enhance efficiency, reduce costs by consolidation, integrate into regional networks, and form alliances or partnerships. To create additional value, the core competency of laboratory professionals must be refocused to provide medical knowledge services (consultative support to clinicians) related to in vitro diagnostic testing. To integrate cost-efficiency with medical quality, implementation of a matricial organization - operational vs. biomedical level - could be an interesting approach. This integrated structure should create total quality of laboratory testing, managing the entire medical diagnostic cycle from the pre-preanalytical to post-postanalytical phase.

  18. Post eLetter Solutions: Healthy Results for Improving Patient Communication Processes at the Royal Hobart Hospital.

    Science.gov (United States)

    Boulter, Rhonda

    2009-06-01

    The primary objective of the Australia Post eLetter project 1 was to determine the feasibility of using the eLetter service with the Patient Administration System Appointment Scheduling Module to provide a fully automated mailing function that would eliminate the need for manual processing of mail delivery. Issues with timely delivery of letters throughout all outpatient sites at the Royal Hobart Hospital (RHH) have been identified as being mainly due to limited human resources being available to perform mailing duties and the like. This new desktop service enables staff to transmit data electronically in conjunction with the appointment software for large quantity mail postings to Australia Post via a secure line. Australia Post then validates the address, appends a barcode, prints the letter, envelopes it and inserts it into the mail distribution network in the state of the recipient. This article depicts the process that has eliminated the manual processing of a letter via the traditional Microsoft application, Wordmate, a system at RHH that was always difficult to use. With the introduction of eLetter, the RHH's Specialist Clinics have significantly improved the timeliness and quality of communication with patients as well as reducing administration tasks for staff.

  19. Mind the gap: 11 years of train-related injuries at the Royal London Hospital Major Trauma Centre.

    Science.gov (United States)

    Virdee, J; Pafitanis, G; Alamouti, R; Brohi, K; Patel, H

    2018-06-18

    Introduction This study presents an extensive retrospective database of patients with polytrauma following train-related injuries and highlights the key lessons learnt in this rare clinical presentation. Materials and methods We retrospectively collected data from 127 patients who presented to Royal London Hospital after sustaining train related trauma. We analysed demographics, accident report data, aetiologies and clinical management interventions. All data were screened and injuries were mapped to various anatomical regions. The revised trauma score, injury severity score and new injury severity scores were used to quantify injury extent. Results Mean patient age was 41 years (range 16-81 years) with a 73% to 27% male to female ratio. Deliberate injuries occurred in 71% of patients, with accidental injury accounting for 29%. The mean new injury severity score was 26.48 (range 1-75), with the most common injuries sustained to the chest and the extremities. Pneumothorax, haemothorax or tension pneumothorax occurred in 44% of patients, with 11% suffering a flail chest injury. Traumatic amputations occurred in 33% of patients and 56% of patients required admission to intensive care. Total mortality rates were 19%, with 12% of patients dying at day 0 and 18% at day 7, respectively. Conclusions This study demonstrated the significant impact of train-related polytrauma and provided a comprehensive injury patterns. It was observed that deliberate polytrauma is related to psychiatric deliberate harm but there is no significant difference in the patterns of injuries between accidental and deliberately caused injuries. Overall injuries to the thorax and extremities were the most severe, demonstrating the highest mean injury scores.

  20. The first lady almoner: the appointment, position, and findings of Miss Mary Stewart at the Royal Free Hospital, 1895-99.

    Science.gov (United States)

    Cullen, Lynsey T

    2013-10-01

    This article examines the professional roots of the hospital almoner, a position which has been widely neglected in medical history. The first almoner was Miss Mary Stewart, a former Charity Organization Society employee, appointed at the Royal Free Hospital of central London in 1895. The Royal Free was a charitable hospital which offered free medical treatment to patients considered morally deserving but unable to afford medical care elsewhere. The role expected of Stewart was to means test patients in order to ensure that only those deemed "appropriate" received free medical treatment, and to establish the extent to which the hospital was being abused by those who could afford to contribute toward their medical care. While in office, Stewart continually reshaped the role of almoner. She fashioned the position into that of a medical social worker and undertook such duties as referring patients to other means of medical and charitable assistance, visiting patients' homes, and training almoners for positions at other voluntary hospitals. Through the examination of Mary Stewart's Almoners Report Book, this article considers the circumstances of her appointment, the role she performed, and the findings of her investigations.

  1. The First Lady Almoner: The Appointment, Position, and Findings of Miss Mary Stewart at the Royal Free Hospital, 1895–99

    Science.gov (United States)

    Cullen, Lynsey T.

    2013-01-01

    This article examines the professional roots of the hospital almoner, a position which has been widely neglected in medical history. The first almoner was Miss Mary Stewart, a former Charity Organization Society employee, appointed at the Royal Free Hospital of central London in 1895. The Royal Free was a charitable hospital which offered free medical treatment to patients considered morally deserving but unable to afford medical care elsewhere. The role expected of Stewart was to means test patients in order to ensure that only those deemed “appropriate” received free medical treatment, and to establish the extent to which the hospital was being abused by those who could afford to contribute toward their medical care. While in office, Stewart continually reshaped the role of almoner. She fashioned the position into that of a medical social worker and undertook such duties as referring patients to other means of medical and charitable assistance, visiting patients' homes, and training almoners for positions at other voluntary hospitals. Through the examination of Mary Stewart's Almoners Report Book, this article considers the circumstances of her appointment, the role she performed, and the findings of her investigations. PMID:22474098

  2. Chromogranin A as a Biochemical Marker for Neuroendocrine Tumors: A Single Center Experience at Royal Hospital, Oman

    Directory of Open Access Journals (Sweden)

    Elham S. Al-Risi

    2017-09-01

    Full Text Available Objectives: To evaluate the significance of serum chromogranin A (CgA status in patients with and without different neuroendocrine tumors (NETs by conducting a retrospective assessment of the diagnostic utility and limitations of CgA as a biomarker for NETs in a tertiary care hospital in Oman. Methods: We conducted a retrospective analysis of CgA requests referred to the Clinical Biochemistry Laboratory, Royal Hospital, Oman over a 24-month period (April 2012 to March 2014. During this time, 302 CgA tests for 270 patients (119 males and 151 females; age range 11–86 years and mean±standard deviation (SD 44.0±18.0 years, were requested. Of these CgA tests, 245 tests were performed for 245 patients investigated for the diagnosis of NETs, and 57 CgA tests were performed for 25 patients with diagnosed NETs who were undergoing follow-up. Serum CgA levels were analyzed using the enzyme-linked immunosorbent assay based on a cut-off value of 22 IU/L. Results: Of the 302 CgA tests reviewed, 197 (65.2% were within the quoted normal range; however, 105 (34.8% had CgA > 22 IU/L. Of the 245 patients with first-line CgA, 38 patients (15.5% had NET that included carcinoid, pheochromocytoma, pancreatic NET, adrenal adenoma, prostatic adenocarcinoma, gastrointestinal NET, medullary thyroid carcinoma, Schwannoma, lung small cell carcinoma, parathyroid adenoma, and pituitary macroadenoma. The mean±SD of CgA in these patients with NETs was 205.0±172.0 IU/L. Meanwhile, there were 45 (18.3% patients with CgA > 22 IU/L (83.0±116.0 IU/L who did not have NETs. The conditions/diseases included: essential hypertension, chronic kidney disease, heart failure, peptic ulcer, chronic diarrhea, use of proton pump inhibitors, and other chronic diseases (hypothyroidism, asthma, diabetes mellitus. Of the 25 patients with known NET who were followed-up, there were 57 CgA results (29 with CgA ≤ 22 IU/L and 28 with CgA > 22 IU/L. The overall clinical sensitivity of CgA in the

  3. Situational leadership styles, staff nurse job characteristics related to job satisfaction and organizational commitment of head nurses working in hospitals under the jurisdiction of the Royal Thai Army.

    Science.gov (United States)

    Intaraprasong, Bhusita; Potjanasitt, Sureporn; Pattaraarchachai, Junya; Meennuch, Chavalit

    2012-06-01

    To analyze the relationships between the situational leadership styles, staff nurse job characteristic with job satisfaction and organizational commitment of head nurses working in hospitals under the jurisdiction of the Royal Thai Army The cross-sectional analytical study was conducted in 128 head nurses working in hospitals under the jurisdiction of the Royal Thai Army. Data were collected by mailed questionnaires. A total of 117 completed questionnaires (91.4%) were received for analysis. Statistical analysis was done using Pearson's Product Moment Correlation Coefficient. It was found that situational leadership styles were not correlated with job satisfaction and organizational commitment of head nurses. Staff nurse job characteristics had a low level of positive correlation with job satisfaction and organizational commitment of head nurses at 0.05 level of significance (r = 0.202 and 0.189 respectively). The hospital administrators should formulate policy to improve working system, human resource management and formulate policies and strategies based on situational leadership. In addition, they should improve the characteristics of staff nurse job by using surveys to obtain job satisfaction and organizational commitment.

  4. Indoor radon measurements in Adelaide, South Australia

    International Nuclear Information System (INIS)

    Paix, D.

    1989-01-01

    In 1986 a study of radon levels in homes in Melbourne was made, using activated charcoal to adsorb the gas from indoor air. Cups containing 25g of activated charcoal were exposed for periods of nominally 7 days. The cups were sealed and the accumulated activity was measured by gamma counting. Cup activity was related to ambient radon concentration by calibrations done in the Australian Radiation Laboratory's radon reference chamber. This work was continued in Adelaide, South Australia (S.A.) between July and November 1986 using the same methods. Cups were exposed in their homes by 213 volunteers from the staff of the S.A. Institute of Technology and the S.A. Health Commission. The median concentration of radon in air was 10 Bq/m 3 , with 90% of values below 35 Bq/m 3 , and 100% below 75 Bq/m 3 . The lower bound of the distribution is poorly defined because of inadequate counting statistics. 4 refs., 6 figs

  5. Introduction of clerking pro forma for surgical spinal patients at the Royal National Orthopaedic Hospital NHS Trust (London): an audit cycle.

    Science.gov (United States)

    Pace, Valerio; Farooqi, Omar; Kennedy, James; Park, Chang; Cowan, Joseph

    2018-05-01

    As a tertiary referral centre of spinal surgery, the Royal National Orthopaedic Hospital (RNOH) handles hundreds of spinal cases a year, often with complex pathology and complex care needs. Despite this, issues were raised at the RNOH following lack of sufficient documentation of preoperative and postoperative clinical findings in spinal patients undergoing major surgery. This is not in keeping with guidelines provided by the Royal College of Surgeons. The authors believe that a standardised clerking pro forma for surgical spinal patients admitted to RNOH would improve the quality of care provided. Therefore, the use of a standard clerking pro forma for all surgical spinal patients could be a useful tool enabling improvements in patients care and safety in keeping with General Medical Council/National Institute for Health and Care Excellence guidelines. An audit (with closure of loop) looking into the quality of the preoperative and postoperative clinical documentation for surgical spinal patients was carried out at the RNOH in 2016 (retrospective case note audit comparing preintervention and postintervention documentation standards). Our standardised pro forma allows clinicians to best utilise their time and standardises examination to be compared in a temporal manner during the patients admission and care. It is the authors understanding that this work is a unique study looking at the quality of the admission clerking for surgical spinal patients. Evidently, there remains work to be done for the widespread utilisation of the pro forma. Early results suggest that such a pro forma can significantly improve the documentation in admission clerking with improvements in the quality of care for patients. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  6. The new woman as librarian the career of Adelaide Hasse

    CERN Document Server

    Beck, Clare

    2006-01-01

    At the time of her death, it seemed that Adelaide Hasse would simply pass from memory and be forgotten. However, by the turn of the century, American Libraries would sanctify her as one of its hundred library leaders of the twentieth century, one of only thirty women given this honor.

  7. A Multi-Methodology for improving Adelaide's Groundwater Management

    Science.gov (United States)

    Batelaan, Okke; Banks, Eddie; Batlle-Aguilar, Jordi; Breciani, Etienne; Cook, Peter; Cranswick, Roger; Smith, Stan; Turnadge, Chris; Partington, Daniel; Post, Vincent; Pool Ramirez, Maria; Werner, Adrian; Xie, Yueqing; Yang, Yuting

    2015-04-01

    Groundwater is a strategic and vital resource in South Australia playing a crucial role in sustaining a healthy environment, as well as supporting industries and economic development. In the Adelaide metropolitan region ten different aquifer units have been identified, extending to more than 500 m below sea level. Although salinity within most of these aquifers is variable, water suitable for commercial, irrigation and/or potable use is predominantly found in the deeper Tertiary aquifers. Groundwater currently contributes only 9000 ML/yr of Adelaide's total water consumption of 216,000 ML, while in the Northern Adelaide Plains 17000 ML/yr is used. However, major industries, market gardeners, golf courses, and local councils are highly dependent on this resource. Despite recent rapid expansion in managed aquifer recharge, and the potential for increased extraction of groundwater, particularly for the commercial and irrigation supplies, little is known about the sources and ages of Adelaide's groundwater. The aim of this study is therefore to provide a robust conceptualisation of Adelaide's groundwater system. The study focuses on three important knowledge gaps: 1. Does groundwater flow from the Adelaide Hills into the sedimentary aquifers on the plains? 2. What is the potential for encroachment of seawater if groundwater extraction increases? 3. How isolated are the different aquifers, or does water leak from one to the other? A multi-tool approach has been used to improve the conceptual understanding of groundwater flow processes; including the installation of new groundwater monitoring wells from the hills to the coast, an extensive groundwater sampling campaign of new and existing groundwater wells for chemistry and environmental tracers analysis, and development of a regional scale numerical model rigorously tested under different scenario conditions. The model allows quantification of otherwise hardly quantifiable quantities such as flow across fault zones and

  8. Matilda, Edgith and Adelaide: conflicts between generations and the doweries of the queens in Germany

    Directory of Open Access Journals (Sweden)

    Giovanni Isabella

    2012-10-01

    Full Text Available The reconstruction of the size and geographical distribution of properties that made up the dowers of the first three Ottonian queens makes possible to see the great importance of these assets, both for their large extension, both for the relevant strategic role dues to their location. Already Henry I, the first king of the dynasty, endowed his wife Matilda with numerous curtes that belonged to the area of oldest and strong presence of the Ottonian family, namely the eastern Saxony and Thuringia. Precisely, the control of these important goods was the cause of the fight between Matilda and her son Otto I when, in 938, the mother supported the claims to the throne of her younger son Henry during a revolt against Otto. The dower of Edgith, the first wife of Otto, was made from the large curtis of Magdeburg, which became a place of great symbolic and political importance thanks to the burial of the royal couple and for its elevation to Archdiocese which was entrusted with the supervision of slavic territories east of the Elbe. The set of the assets granted in Germany by Otto to Adelaide, his second wife, it's difficult to reconstruct in detail, but it was definitely of great extent in continuity with the dower of Matilda, although compared to this the curtes were spread across a wider area encompassing both the eastern Saxony and Thuringia, both Alsace and Franconia.

  9. Greening and “un”greening Adelaide, South Australia

    Directory of Open Access Journals (Sweden)

    Guy M. Robinson

    2015-06-01

    Full Text Available The original design for Adelaide, the capital city of the state of South Australia, incorporated a green belt (known as the Park Lands around the city centre, itself laid out on a one square mile (2.59 km2 grid and including five large public squares. The Park Lands provided a barrier to urban sprawl and covered approximately 9.31 km2, of which 1.53 km2 has been used subsequently for cultural institutions, railways, cemeteries, sporting facilities and other constructions. In addressing issues of greening pertaining to Adelaide, the Park Lands and its management represents a core element in the evolving history of the city's growth. This paper will consider some of the contradictions within this growth, examining the changing attitudes of government and the populace to the Park Lands and also to the increasing sprawl of the city. It can be argued that this sprawl has been antithetical to maintenance of biodiversity and principles of “greening”, not only during the main phase of expansion in the 1960s and 1970s but also in recent years when planned development on prime farmland and other “green” areas is contributing to problems for provision of transport infrastructure and generally reducing capacity for sustainability. The potential for conflict between the desire to maintain biodiversity versus protection for the growing number of people moving into bushfire risk areas is just one of several examples of problems arising as a result of a relaxed attitude to low-density expansion. In examining these problems the paper will present maps of the changing footprint of Adelaide and will elaborate new “greening” initiatives that include green roofs, new systems of water harvesting, community-supported agriculture and schemes directly aimed at creating low-carbon living. A consistent theme will be the contradictions within plans for the city between greening and “un”greening.

  10. The reliability of the Adelaide in-shoe foot model.

    Science.gov (United States)

    Bishop, Chris; Hillier, Susan; Thewlis, Dominic

    2017-07-01

    Understanding the biomechanics of the foot is essential for many areas of research and clinical practice such as orthotic interventions and footwear development. Despite the widespread attention paid to the biomechanics of the foot during gait, what largely remains unknown is how the foot moves inside the shoe. This study investigated the reliability of the Adelaide In-Shoe Foot Model, which was designed to quantify in-shoe foot kinematics and kinetics during walking. Intra-rater reliability was assessed in 30 participants over five walking trials whilst wearing shoes during two data collection sessions, separated by one week. Sufficient reliability for use was interpreted as a coefficient of multiple correlation and intra-class correlation coefficient of >0.61. Inter-rater reliability was investigated separately in a second sample of 10 adults by two researchers with experience in applying markers for the purpose of motion analysis. The results indicated good consistency in waveform estimation for most kinematic and kinetic data, as well as good inter-and intra-rater reliability. The exception is the peak medial ground reaction force, the minimum abduction angle and the peak abduction/adduction external hindfoot joint moments which resulted in less than acceptable repeatability. Based on our results, the Adelaide in-shoe foot model can be used with confidence for 24 commonly measured biomechanical variables during shod walking. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Piloting a mass gathering conceptual framework at an Adelaide schoolies festival.

    Science.gov (United States)

    Hutton, Alison; Munt, Rebecca; Zeitz, Kathryn; Cusack, Lynette; Kako, Mayumi; Arbon, Paul

    2010-01-01

    During the summer months in Australia, school leavers celebrate their end of school life at schoolies festivals around the nation. These events are typically described as a mass gathering as they are an organised event taking place within a defined space, attended by a large number of people. A project was undertaken to analyse the usefulness of Arbon's (2004) conceptual model of mass gatherings in order to develop a process to better understand the Adelaide Schoolies Festival. Arbon's conceptual framework describes the inter-relationship between the psychosocial, environmental and bio-medical domains of a mass gathering. Each domain has set characteristics which help to understand the impact on the mass gathering event. The characteristics within three domains were collected using field work and bio-medical data to examine the relationship between injury and illness rates. Using the conceptual framework to evaluate this schoolies event helped create an understanding of the physiology, environment and behaviour contributing to patient presentations. Results showed that the schoolies crowd was active and energetic, and the main crowd behaviour observed was dancing and socialising with friends. The environmental domain was characterised by a grassy outdoor venue that was bounded and dry. Due to the overall health of the crowd, activities undertaken and the supportive environment, the majority of injuries to schoolies were minor (68%). However, twenty-four percent of schoolies who presented with alcohol related illness were found to have consumed alcohol at risky levels; half of this cohort was transported to hospital. The conceptual framework successfully guided a higher level of examination of the mass gathering event. In particular, the framework facilitated a greater understanding of the inter-relationships of the various characteristics of a mass gathering event, in this case the Adelaide Schoolies Festival.

  12. Fast-food exposure around schools in urban Adelaide.

    Science.gov (United States)

    Coffee, Neil T; Kennedy, Hannah P; Niyonsenga, Theo

    2016-12-01

    To assess whether exposure to fast-food outlets around schools differed depending on socio-economic status (SES). Binary logistic regression was used to investigate the presence and zero-inflated Poisson regression was used for the count (due to the excess of zeroes) of fast food within 1000 m and 15000 m road network buffers around schools. The low and middle SES tertiles were combined due to a lack of significant variation as the 'disadvantaged' group and compared with the high SES tertile as the 'advantaged' group. School SES was expressed using the 2011 Australian Bureau of Statistics, socio-economic indices for areas, index of relative socio-economic disadvantage. Fast-food data included independent takeaway food outlets and major fast-food chains. Metropolitan Adelaide, South Australia. A total of 459 schools were geocoded to the street address and 1000 m and 1500 m road network distance buffers calculated. There was a 1·6 times greater risk of exposure to fast food within 1000 m (OR=1·634; 95 % 1·017, 2·625) and a 9·5 times greater risk of exposure to a fast food within 1500 m (OR=9·524; 95 % CI 3·497, 25·641) around disadvantaged schools compared with advantaged schools. Disadvantaged schools were exposed to more fast food, with more than twice the number of disadvantaged schools exposed to fast food. The higher exposure to fast food near more disadvantaged schools may reflect lower commercial land cost in low-SES areas, potentially creating more financially desirable investments for fast-food developers.

  13. A royal visit

    CERN Multimedia

    2006-01-01

    King Harald V and Queen Sonja of Norway made a trip to CERN on Tuesday 4 April, taking a tour of part of the LHC and greeting the Norwegian students and scientists at the Laboratory. Norway's King Harald V and Queen Sonja take a tour of the ATLAS detector with CERN Director-General Robert Aymar.King Harald V and Queen Sonja are greeted warmly by members of the Norwegian community at the CERN Globe. CERN Director-General Robert Aymar welcomed the royal party, which included the Norwegian Minister of Foreign Affairs, Jonas Gahr Støre, and provided an overview of CERN's history and current and future research. ATLAS deputy spokesperson Steinar Stapnes then quickly explained the concept and inner workings of the LHC, some LHC physics goals and ATLAS, which is one of the main experiments receiving Norwegian contributions. 'I don't think I've ever had so many distinguished students before,' Stapnes said jokingly to the crowd.The royal delegation was then escorted underground for a look at the LHC tunnel and the...

  14. Governing Carbon Mitigation and Climate Change within Local Councils: A Case Study of Adelaide, South Australia

    Directory of Open Access Journals (Sweden)

    Heather Zeppel

    2012-08-01

    Full Text Available There is growing concern about climate change impacts on local government areas. In Australia, the federal carbon tax (from 1 July 2012 will also increase costs for local councils. This paper evaluates what carbon mitigation (i.e. energy, water, and waste management actions have been implemented by metropolitan Adelaide councils (n=14 and why (or why not. A survey of environmental officers profiled carbon mitigation actions, emissions auditing, and motives for emissions reduction by Adelaide councils. The main reasons for adopting carbon actions were a climate change plan, climate leadership, and cost savings. Internal council governance of climate change actions was also evaluated. A climate governance framework based on adaptive management, communication, and reflective practice (Nursey-Bray 2010 was applied to assess climate mitigation by Adelaide councils.

  15. Impact of two recent extreme heat episodes on morbidity and mortality in Adelaide, South Australia: a case-series analysis

    Directory of Open Access Journals (Sweden)

    Williams Susan

    2011-05-01

    Full Text Available Abstract Background Extreme heatwaves occurred in Adelaide, South Australia, in the summers of 2008 and 2009. Both heatwaves were unique in terms of their duration (15 days and 13 days respectively, and the 2009 heatwave was also remarkable in its intensity with a maximum temperature reaching 45.7°C. It is of interest to compare the health impacts of these two unprecedented heatwaves with those of previous heatwaves in Adelaide. Methods Using case-series analysis, daily morbidity and mortality rates during heatwaves (≥35°C for three or more days occurring in 2008 and 2009 and previous heatwaves occurring between 1993 and 2008 were compared with rates during all non-heatwave days (1 October to 31 March. Incidence rate ratios (IRRs were established for ambulance call-outs, hospital admissions, emergency department presentations and mortality. Dose response effects of heatwave duration and intensity were examined. Results Ambulance call-outs during the extreme 2008 and 2009 events were increased by 10% and 16% respectively compared to 4.4% during previous heatwaves. Overall increases in hospital and emergency settings were marginal, except for emergency department presentations in 2008, but increases in specific health categories were observed. Renal morbidity in the elderly was increased during both heatwaves. During the 2009 heatwave, direct heat-related admissions increased up to 14-fold compared to a three-fold increase seen during the 2008 event and during previous heatwaves. In 2009, marked increases in ischaemic heart disease were seen in the 15-64 year age group. Only the 2009 heatwave was associated with considerable increases in total mortality that particularly affected the 15-64 year age group (1.37; 95% CI, 1.09, 1.71, while older age groups were unaffected. Significant dose-response relationships were observed for heatwave duration (ambulance, hospital and emergency setting and intensity (ambulance and mortality. Conclusions While

  16. UK Royal Navy WWII Logbooks

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In 2006, the UK and NOAA's Climate Database Modernization Program (CDMP) funded the imaging of approximately 8,000 Royal Navy logbooks in the UK National Archives...

  17. Daily variation of urban heat island effect and its correlations to urban greenery: A case study of Adelaide

    Directory of Open Access Journals (Sweden)

    Ali Soltani

    2017-12-01

    Full Text Available Urban structure and landscape cause an artificial temperature increase in cities, known as the urban heat island effect. The magnitude of such urban–rural temperature difference varies in daily and seasonal basis. Daily patterns of urban heat accumulation in Adelaide is under investigation. In this paper, East–West air temperature profile of Adelaide metropolitan area was mapped in 60 journeys alongside a straight cross route connecting Adelaide Hills to the West Beach under clear sky between 26 July and 15 August 2013. The most intense urban–rural temperature differences of 5.9 °C occurred during midnight in Adelaide. However, maximum urban heat variation occurred during the late afternoon when the near-surface urban heat fluctuates by 2 °C between the CBD East and Western Parklands. During summer heatwaves, the afternoon heat stress limits public life vibrancy in Adelaide. Increased urban greenery can facilitate resilience to heat by providing shadow and evaporative cooling. A better understanding of daily urban heat variations and the cooling effect of urban greenery assists urban policy making and public life management in the context of climate change.

  18. Attitudes and experiences of restaurateurs regarding smoking bans in Adelaide, South Australia

    OpenAIRE

    Jones, K.; Wakefield, M.; Turnbull, D.

    1999-01-01

    OBJECTIVES—To determine compliance with a voluntary code of practice (VCP) for restricting smoking in restaurants and to canvass the attitudes of restaurateurs towards tougher smoking restrictions.
DESIGN—Cross-sectional survey conducted in 1996 using a telephone questionnaire.
SETTING—Metropolitan restaurants and cafés in Adelaide, South Australia.
PARTICIPANTS—276 (86.8%) of a sample of randomly selected owners and managers.
MAIN OUTCOME MEASURES—Restaurant non-smoking policies, reported an...

  19. Predictors of podiatry utilisation in Australia: the North West Adelaide Health Study.

    Science.gov (United States)

    Menz, Hylton B; Gill, Tiffany K; Taylor, Anne W; Hill, Catherine L

    2008-08-19

    Foot problems are highly prevalent in the community; however no large population-based studies have examined the characteristics of those who do and do not access podiatry services in Australia. The aim of this study was to explore patterns of podiatry utilisation in a population-based sample of people aged 18 years and over living in the northwest region of Adelaide, South Australia. The North West Adelaide Health Study is a representative longitudinal cohort study of 4,060 people randomly selected and recruited by telephone interview. The interview included questions regarding healthcare service utilisation in the past year. Data were also collected on education, income and major medical conditions. Overall, 9.5% of the total sample and 17.7% of those who reported foot pain had attended a podiatrist in the past year. Participants who had accessed podiatry treatment were more likely to be female, be aged over 45 years, be obese, and have major chronic medical conditions (osteoporosis, osteoarthritis, diabetes, cardiovascular disease and high blood pressure). Those who reported foot pain but had not accessed a podiatrist were more likely to be male and be aged 20 to 34 years. Only a small proportion of people who report foot pain have accessed podiatry services in the past year. There is a need to further promote podiatry services to the general community, particularly to men and younger people.

  20. Predictors of podiatry utilisation in Australia: the North West Adelaide Health Study

    Directory of Open Access Journals (Sweden)

    Taylor Anne W

    2008-08-01

    Full Text Available Abstract Background Foot problems are highly prevalent in the community; however no large population-based studies have examined the characteristics of those who do and do not access podiatry services in Australia. The aim of this study was to explore patterns of podiatry utilisation in a population-based sample of people aged 18 years and over living in the northwest region of Adelaide, South Australia. Methods The North West Adelaide Health Study is a representative longitudinal cohort study of 4,060 people randomly selected and recruited by telephone interview. The interview included questions regarding healthcare service utilisation in the past year. Data were also collected on education, income and major medical conditions. Results Overall, 9.5% of the total sample and 17.7% of those who reported foot pain had attended a podiatrist in the past year. Participants who had accessed podiatry treatment were more likely to be female, be aged over 45 years, be obese, and have major chronic medical conditions (osteoporosis, osteoarthritis, diabetes, cardiovascular disease and high blood pressure. Those who reported foot pain but had not accessed a podiatrist were more likely to be male and be aged 20 to 34 years. Conclusion Only a small proportion of people who report foot pain have accessed podiatry services in the past year. There is a need to further promote podiatry services to the general community, particularly to men and younger people.

  1. World Solar Challenge 1993 Technical Report. Part 1. Darwin to Adelaide. (November 7-November 16, 1993)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-01-01

    This is a report of the above-named solar car race from Darwin to Adelaide, Australia. On January 7, 1983, an Australian adventurer Mr. Hans Tholstrup succeeded in running from the Australian west coast to Sydney in a car driven solely by solar energy. The travel took 20 days, at an average speed of 23km per hour. The technology has made remarkable advances since his success and, in the World Solar Challenge 1993 held in November 1993, a Honda team crossed the Australian Continent at an average speed of 85km per hour. Technical challenges included the development of maximum-output solar cell panels, a car designed to make full use of such power, and a run at the maximum possible speed, all these dependent solely on the sun as energy source. This report Part I contains the details of the race, analysis, aerodynamics, car body structure, manufacture, materials, and so forth. (NEDO)

  2. World Solar Challenge 1993 Technical Report. Part 2. Darwin to Adelaide. (November 7-November 16, 1993)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-01-01

    This is a report of the above-named solar car race from Darwin to Adelaide, Australia. In this Part II, details are described of motors, controllers, transmissions, batteries, battery management, suspensions, travelling wheels, tires, strategies, communications, weather prediction, safety, and so forth. As for motors, a regenerative motor which generates power during car deceleration may also be used. Nineteen manufacturers and six teams used various kinds of motors. One was equipped with a wheel motor devoid of a transmission, with the motor built into the wheel. While it is possible to drive across the continent without a storage battery as in the case of the 1990 event, one should be installed, to be stored up under favorable conditions for use in hill climbing. For the Honda and Nissan teams, tough and efficient batteries, though not high in energy density, were selected. (NEDO)

  3. Googling Service Boundaries for Endovascular Clot Retrieval Hub Hospitals in a Metropolitan Setting: Proof-of-Concept Study.

    Science.gov (United States)

    Phan, Thanh G; Beare, Richard; Chen, Jian; Clissold, Benjamin; Ly, John; Singhal, Shaloo; Ma, Henry; Srikanth, Velandai

    2017-05-01

    There is great interest in how endovascular clot retrieval hubs provide services to a population. We applied a computational method to objectively generate service boundaries for such endovascular clot retrieval hubs, defined by traveling time to hub. Stroke incidence data merged with population census to estimate numbers of stroke in metropolitan Melbourne, Australia. Traveling time from randomly generated addresses to 4 endovascular clot retrieval-capable hubs (Royal Melbourne Hospital [RMH], Monash Medical Center [MMC], Alfred Hospital [ALF], and Austin Hospital [AUS]) estimated using Google Map application program interface. Boundary maps generated based on traveling time at various times of day for combinations of hubs. In a 2-hub model, catchment was best distributed when RMH was paired with MMC (model 1a, RMH 1765 km 2 and MMC 1164 km 2 ) or with AUS (model 1c, RMH 1244 km 2 and AUS 1685 km 2 ), with no statistical difference between models ( P =0.20). Catchment was poorly distributed when RMH was paired with ALF (model 1b, RMH 2252 km 2 and ALF 676 km 2 ), significantly different from both models 1a and 1c (both P AUS was superior to that of RMH, MMC, and ALF in catchment distribution and travel time. The method was also successfully applied to the city of Adelaide demonstrating wider applicability. We provide proof of concept for a novel computational method to objectively designate service boundaries for endovascular clot retrieval hubs. © 2017 American Heart Association, Inc.

  4. Does Royal jelly affect tumor cells?

    Directory of Open Access Journals (Sweden)

    Shirzad Maryam

    2013-04-01

    Full Text Available Introduction: Royal jelly is a substance that appears to be effective on immune system and it appears to be effective on both prevention and growth of cancer cells. In this study, we aimed to carry out a research to investigate the effect of royal jelly on the growth of WEHI-164 fibrosarcoma cell in syngenic Balb/c mice. Methods: In an experimental study, 28 male Balb/c mice were designated into four equal groups. The mice were subcutaneously injected with 5x105 WEHI-164 tumor cells on the day zero in the chest area of the animal. Animals in groups 1 to 4 were orally given 100, 200, 300 mg/kg of royal jelly or vehicle, respectively. In every individual mouse, the tumour size was measured every 2 days from day 5 (days 5, 7, 9, 11, 13, 15 and 17. Data were statistically analyzed using Kruskal-Wallis and Mann Whitney-U tests. Result: Our results showed that the mean size of tumor in case group was significantly smaller than the control group in days 11, 13, 15 and 17 (P<0.05. No metastasis was seen in test and control groups. Conclusion: With emphasize on antitumor effect of royal jelly, it seems that royal jelly has important role in control and regression of fibrosarcoma cells. Since royal jelly showed a delayed effect in control of fibrosarcoma, we suggest that royal jelly be used at least 10 days before tumor inoculation.

  5. Geochemical and isotopic tracers of recharge and reclamation of stormwater in an urban aquifer: Adelaide, South Australia

    International Nuclear Information System (INIS)

    Herczeg, A.L.; Rattray, K.J.; Dillon, P.J.; Pavelic, P.C.; Barry, K.J.

    2002-01-01

    Artificial recharge and reclamation of stormwater into groundwater is a newly developing strategy to augment water resources in the Adelaide metropolitan area of South Australia. Mixing between injected storm water and native groundwater can be most effectively using naturally occurring chloride ion. Stable isotopes of the water molecule are used more effectively during short term tests (i.e., immediately following injection events), and requires frequent monitoring of the surface water end-member. Biogeochemical processes involving geochemical reactions such as organic matter oxidation, carbonate mineral dissolution and sulfide mineral oxidation are very effectively traced by δ 13 C and 14 C (of TDIC) and δ 34 S (of SO 4 2- ). The most important processes occurring in the Tertiary limestone aquifer in Adelaide were carbonate mineral dissolution which is induced largely by CO 2 production during organic matter oxidation. Sulfide mineral oxidation is a minor process, and is accompanied by an equivalent amount of sulfate reduction after injection of the stormwater. (author)

  6. Hospitals

    Data.gov (United States)

    Department of Homeland Security — This database contains locations of Hospitals for 50 states and Washington D.C. , Puerto Rico and US territories. The dataset only includes hospital facilities and...

  7. Key Royale bridge five year evaluation.

    Science.gov (United States)

    2013-06-01

    This report describes the design, construction, instrumentation, and five-year evaluation of the Key Royale Bridge substructure. The primary focus was the evaluation of the implementation of highly reactive supplementary cementitious materials (SCM) ...

  8. Biological Activities of Royal Jelly - Review

    Directory of Open Access Journals (Sweden)

    Crenguţa I. Pavel

    2011-10-01

    Full Text Available Royal jelly is a secretion product of the cephalic glands of nurse bees that has been used for centuries for itsextraordinary properties and health effects. This bibliographic study aims to review many of the scientific findingsand research that prove many of the remarkable various actions, effects and some uses of royal jelly. There are takeninto consideration numerous biological properties and effects of royal jelly: antioxidant, neurotrophic, hipoglicemiant, hipocholesterolemiant and hepatoprotective, hypotensive and blood pressure regulatory, antitumor, antibiotic, anti-inflammatory, immunomodulatory and anti-allergic, general tonic and antiaging. Royal jelly is one ofthe most studied bee products, but there still remains much to reveal about its biochemistry and biological activity infuture research for our health and life benefit.

  9. Attitudes and experiences of restaurateurs regarding smoking bans in Adelaide, South Australia.

    Science.gov (United States)

    Jones, K; Wakefield, M; Turnbull, D A

    1999-01-01

    To determine compliance with a voluntary code of practice (VCP) for restricting smoking in restaurants and to canvass the attitudes of restaurateurs towards tougher smoking restrictions. Cross-sectional survey conducted in 1996 using a telephone questionnaire. Metropolitan restaurants and cafes in Adelaide, South Australia. 276 (86.8%) of a sample of randomly selected owners and managers. Restaurant non-smoking policies, reported and anticipated change in business, and restaurateurs' attitudes towards smoking restrictions. 26.8% of restaurants had a total smoking ban; 40.6% restricted smoking some other way; and 32.6% permitted unrestricted smoking. Only 15.1% of restaurants with a ban or restrictions had used the VCP to guide the development of their policy, and only half of these were complying with it. Although 78.4% of those with bans and 84.4% of those with restrictions reported that their non-smoking policy had been associated with either no change or a gain in business, only 33.3% of those allowing unrestricted smoking expected that this would be the case, if they were to limit smoking. A total of 50.4% of restaurateurs, including 45.3% of those with no restrictions, agreed that the government should ban smoking in all restaurants. The VCP made an insignificant contribution to adoption of non-smoking policies, and compliance with the code was poor. Despite concerns about loss of business, there was considerable support for legislation which would ban smoking in all dining establishments.

  10. Periodontal disease among 45-54 year olds in Adelaide, South Australia.

    Science.gov (United States)

    Brennan, D S; Spencer, A J; Roberts-Thomson, K F

    2007-03-01

    The aims of this study were to describe the prevalence, extent and severity of periodontal disease among middle-aged adults, and to examine periodontitis by dental visit pattern, dental and health behaviour, socio-demographics and socioeconomic status. A random sample of 45-54 year olds from metropolitan Adelaide, South Australia was surveyed by mailed self-complete questionnaire during 2004-2005 with up to four follow-up mailings of the questionnaire to non-respondents (n=879 responded, response rate = 43.8 per cent). Oral examinations were performed on 709 people who responded to the questionnaire (completion rate=80.7 per cent), providing an assessment of periodontal status. Prevalence of loss of attachment (LOA) of 6+ mm was 19.2 per cent, extent of sites with LOA of 6+ mm was 1.3 per cent, and severity of LOA of sites with LOA of 2+ mm was 2.4mm. Using a case definition for periodontitis of two or more sites with LOA of 5+ mm and one or more sites with PD of 4+ mm in a multivariate logistic regression showed higher odds of periodontitis for people who last visited for relief of pain (OR = 1.93) and who smoked daily/occasionally (OR = 3.84), while lower odds were observed for people who were born in Australia (OR = 0.51) and spoke English as the main language at home (OR = 0.34). While periodontal disease was related to visit pattern and health-related behaviours, the relationship with place of birth and main language spoken at home indicated socio-cultural variation in disease not explained by behaviour among this cohort of 45-54 year olds.

  11. Understanding the evolution of multimorbidity: evidences from the North West Adelaide Health Longitudinal Study (NWAHS.

    Directory of Open Access Journals (Sweden)

    Guillaume Ruel

    Full Text Available OBJECTIVE: The aim of this study is to describe the evolution of multimorbidity. STUDY DESIGN AND SETTING: Data from 1854 South Australians who participated in the North West Adelaide longitudinal Health Study (NWAHS was collected between baseline (2000-2002 and follow-up (2008-2010. Status for eight chronic diseases (CDs was determined by biomedical measurement or self-report. Chronic disease (CD mean age of occurrence and order of appearance was investigated. RESULTS: The prevalence of multimorbidity increased from 32% to 64% during the 7.8±1.1 years of follow-up. The estimated mean age of onset of a new CD was significantly older for hypertension, cardiovascular disease (CVD and chronic obstructive pulmonary disease (COPD and younger for hypercholesterolemia, asthma and other mental problem. Hypercholesterolemia was more likely to develop as a first than as a subsequent CD (39%vs.16%, p<0.0001 while CVD (1%vs.5%, p<0.0001, diabetes (5%vs.11%, p<0.001 and COPD (6%vs.16%, p<0.0001 were less likely. The presence of mood disorders at baseline was associated with an increased risk of developing other mental disorders (36%vs.12%, p<0.0001, diabetes (18%vs.9%, p<0.01 and asthma (30%vs.21%, p<0.05. CONCLUSION: Longitudinal data could be used to study the evolution of multimorbidity and could provide information on CDs mean age of occurrence, order of appearance and impact on the development of future CDs.

  12. Quality Parameters for Commercial Royal Jelly

    Directory of Open Access Journals (Sweden)

    Carmen Ioana Muresan

    2016-01-01

    Full Text Available Royal jelly has become a high-value commercial product and the standardization of this product is required to guarantee its quality on the market. The objective of the research activity was to pursue the chemical composition of commercial samples of Royal Jelly in Romania in order to propose standardization for this product. The physico-chemical composition of commercial Royal Jelly samples was analysed by determining quality parameters like: carbohydrates, lipids, proteins, 10-hydroxy-2-decenoic acid (10-HDA and mineral elements. Carbohydrates analysis showed values between 3.4 % and 5.87 % for fructose, 4.12 % and 7.05 % for glucose, while for sucrose the values ranged between 0.95 % and 2.56 % (determined by HPLC-RI. The lipids content ranged between 1.85 % and 6.32 % (determined by the Soxhlet method. The protein values extended from 13.10 % (RJ2 to 17.04 % (RJ10 (the total protein content was determined by the Kjeldahl method. The values for the major fatty acid in Royal Jelly, 10-HDA, ranged between 1.35 % (RJ8 and 2.03 % (RJ10 (determined by high-performance liquid chromatography. The concentration of minerals varied between 3188.70 mg/kg and 4023.39 mg/kg (the concentration of minerals was measured using flame atomic absorption spectrometry. Potassium, followed by magnesium, sodium and calcium, occurs in the highest concentrations. The commercial Royal Jelly samples analysed presented variable physico-chemical characteristics that correspond with the values given by international quality standard proposals for Royal Jelly.

  13. Royal Dutch Petroleum Company annual report 1992

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    The Royal Dutch Petroleum Company has no operations of its own and virtually the whole of its income derives from its 60% interest in the companies known collectively as the Royal Dutch/Shell Group of Companies; the other 40% is owned by the Shell Transport and Trading Company, p.l.c. The company is engaged in the oil, natural gas, chemicals, coal and metals businesses throughout the world. The annual report summarises the year's results and analyses earnings in each industry segment. Financial statements for the year ended 31 December 1992 are presented. The Group companies' estimated net quantities of crude oil, natural gas and coal are given

  14. Royal Ahold: A Failure Of Corporate Governance

    NARCIS (Netherlands)

    A. de Jong (Abe); D.V. DeJong; G.M.H. Mertens (Gerard); P.G.J. Roosenboom (Peter)

    2005-01-01

    textabstractRoyal Ahold (Koninklijke Ahold NV) was one of the major success stories in the 1990s and is one of the major failures in corporate governance, suffering a complete meltdown in 2003. This clinical study analyzes Ahold’s growth strategy through acquisitions and isolates the cause of the

  15. Isaac Newton and the Royal Mint

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 11; Issue 12. Isaac Newton and the Royal Mint. Biman Nath. Article-in-a-Box Volume 11 Issue 12 December 2006 pp 6-7. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/011/12/0006-0007 ...

  16. Royal Naval nursing: 'testing but worth it'.

    Science.gov (United States)

    Moore, Alison

    2014-08-19

    Inga Kennedy is the most senior nurse in the Royal Navy. She enjoys the commitment and discipline required by a career in the armed forces and says the work offers great opportunities for nurses. Her career highlights have included checking that injured personnel in Afghanistan were receiving the best care possible.

  17. A historical vignette (20). A royal otitis.

    Science.gov (United States)

    Tainmont, J

    2010-01-01

    A royal otitis. The young king of France, Francis II, the eldest son of Henry II and Catherine de Medici, died in Orleans from the effects of the complications of a chronic otitis on 6 December 1560. Based on texts of the time, the paper discusses the nature of the illness, the treatment, and the medical and political entourage of the king.

  18. Sociomateriality at the Royal Court of IS

    DEFF Research Database (Denmark)

    Kautz, Karlheinz; Jensen, Tina Blegind

    2013-01-01

    understanding of the notion of sociomateriality and its use in the IS discipline. We invite the reader to attend a prolonged monologue – characterized by honesty, frank observations and wit – at the royal court of IS. The monologue is delivered by the court jester and directed to the two sovereigns who, based...

  19. Hospitals

    DEFF Research Database (Denmark)

    Mullins, Michael

    2013-01-01

    The challenge could be briefly seen in these terms: hospitals as places for treatment where there’s a technology focus and hospitals for healing where there’s a human focus. In the 60s - 70s wave of new hospital building, an emphasis on technology can be seen. It’s time to move from the technology...... focus. It is not enough to consider only the factors of function within architecture, hygiene, economy and logistics. We also need to look at aspects of aesthetics, bringing nature into the building, art, color, acoustics, volume and space as we perceive them. Contemporary methods and advances...... placed, accessible, provided with plenty of greenery, and maximize sensory impressions, providing sounds, smells, sight and the possibility to be touched. This is a very well documented area I can say. Hygiene, in terms of architecture can give attention to hand wash facilities and their positioning...

  20. ANTIBACTERIAL EFFECTS OF FRESH AND PRESERVED ROYAL JELLY

    Directory of Open Access Journals (Sweden)

    Zinka Maksimović

    2013-10-01

    Full Text Available Antibacterial effects of the fresh royal jelly, royal jelly stored at 4 °C and -40 °C for a period of 12 months against reference and isolated bacterial strains from the different clinical samples, were tested and compared by the diffusion test. Royal jelly shows antibacterial effects against both tested gram-positive and gram-negative bacteria. Fresh royal jelly has the most effective antibacterial activity. Storage temperature at -40 oC slightly affects antibacterial activity of royal jelly, while storage temperature at 4 oC decreases its antibacterial activity.Key words: royal jelly, antibacterial effects, storage temperature, storage duration

  1. Awareness of and Attitudes towards Heat Waves within the Context of Climate Change among a Cohort of Residents in Adelaide, Australia

    OpenAIRE

    Akompab, Derick; Bi, Peng; Williams, Susan; Grant, Janet; Walker, Iain; Augoustinos, Martha

    2012-01-01

    Heat waves are a public health concern in Australia and unprecedented heat waves have been recorded in Adelaide over recent years. The aim of this study was to examine the perception and attitudes towards heat waves in the context of climate change among a group of residents in Adelaide, an Australian city with a temperate climate. A cross-sectional study was conducted in the summer of 2012 among a sample of 267 residents. The results of the survey found that television (89.9%), radio (71.2%)...

  2. Inca Royal Estates in the Sacred Valley

    Science.gov (United States)

    McKim Malville, J.

    The royal estates lying between Cusco and Machu Picchu illustrate the remarkable variety by which the sun was honored and worshipped in the Inca Empire. The terraced basins of Moray combine the sun at both solstices and, perhaps, the zenith sun, with flowing water and offerings to Pachamama. The complex astronomy at Urubamba involves the palace of Quespiwanka, horizon pillars, solstices, and mountain worship. Ollantaytambo contains horizontal shadow-casting gnomons with a major water shrine.

  3. Creating the Royal Society's Sylvester Medal

    OpenAIRE

    Cantor, G.

    2004-01-01

    Following the death of James Joseph Sylvester in 1897, contributions were collected in order to mark his life and work by a suitable memorial. This initiative resulted in the Sylvester Medal, which is awarded triennially by the Royal Society for the encouragement of research into pure mathematics. Ironically the main advocate for initiating this medal was not a fellow mathematician but the chemist and naturalist Raphael Meldola. Religion, not mathematics, provided the link between Meldola and...

  4. What Counts as Quality in Education? Australian College of Educators (ACE) National Conference Proceedings (Adelaide, Australia, September 11-12, 2014)

    Science.gov (United States)

    Ghirelli, Paola S., Ed.

    2014-01-01

    The 2014 Australian College of Educators (ACE) National Conference was held September 11-12 in Adelaide, Australia, with the theme, "What counts as quality in education?" There has been concern with a general downward trend in Australia's performance on international measures of student achievement, but there is equal concern over the…

  5. Chemical Composition and Antimicrobial Activity of Royal Jelly - Review

    Directory of Open Access Journals (Sweden)

    Lavinia Ioana Bărnuţiu

    2011-10-01

    Full Text Available The present paper presents the literature data regarding the chemical composition and antimicrobial activity of RoyalJelly. Royal Jelly is a secretion from the hypofaringeal glands of worker bees which serves as a food for queen beeand to the growing up larvae. Having biological properties already proven, Royal Jelly has considerable commercialappeal and is today used in many sectors (pharmaceutical, food industries and cosmetic products. Thephysicochemical composition of pure royal jelly are analyzed by determining moisture, ash, lipids, proteins,vitamins,aminoacids, carbohydrates, 10-HDA; RJ is the key substance in the antimicrobial function of the system Apismellifera. The intact Royal Jelly exhibited the highest antibacterial activity.

  6. William Henry Bragg, man and scientist, Nobel Laureate and First Professor of Physics, University of Adelaide 1886-1909.

    Science.gov (United States)

    Patterson, John; George, Robert

    2018-03-01

    In London, November 1915, a telegram was received at the home of William Henry Bragg from the secretary of the Academy of Science in Stockholm announcing the award of the Nobel Prize in Physics for "the analysis of crystal structures by means of X-rays". A second similar telegram was addressed to his 25 year old son William Lawrence Bragg (Jenkin, 2008). This article commemorates the centenary of that event and the unveiling of a bust of Sir William Bragg alongside that of his son, Sir Lawrence Bragg, on North Terrace in Adelaide where he spent 23 years of his early career. Copyright © 2018. Published by Elsevier Ltd.

  7. Awareness of and Attitudes towards Heat Waves within the Context of Climate Change among a Cohort of Residents in Adelaide, Australia

    Directory of Open Access Journals (Sweden)

    Iain A. Walker

    2012-12-01

    Full Text Available Heat waves are a public health concern in Australia and unprecedented heat waves have been recorded in Adelaide over recent years. The aim of this study was to examine the perception and attitudes towards heat waves in the context of climate change among a group of residents in Adelaide, an Australian city with a temperate climate. A cross-sectional study was conducted in the summer of 2012 among a sample of 267 residents. The results of the survey found that television (89.9%, radio (71.2%, newspapers (45.3% were the main sources from which respondents received information about heat waves. The majority of the respondents (73.0% followed news about heat waves very or somewhat closely. About 26.6% of the respondents were extremely or very concerned about the effects of heat waves on them personally. The main issues that were of personal concern for respondents during a heat wave were their personal comfort (60.7%, their garden (48.7%, and sleeping well (47.6%. Overall, respondents were more concerned about the impacts of heat waves to the society than on themselves. There was a significant association between gender (χ² = 21.2, df = 3, p = 0.000, gross annual household income (p = 0.03 and concern for the societal effects of heat waves. Less than half (43.2% of the respondents believed that heat waves will extremely or very likely increase in Adelaide according to climate projections. Nearly half (49.3% believed that the effects of heat waves were already being felt in Adelaide. These findings may inform the reframing and communication strategies for heat waves in Adelaide in the context of climate change.

  8. Rare royal families in honeybees, Apis mellifera

    Science.gov (United States)

    Moritz, Robin F. A.; Lattorff, H. Michael G.; Neumann, Peter; Kraus, F. Bernhard; Radloff, Sarah E.; Hepburn, H. Randall

    2005-10-01

    The queen is the dominant female in the honeybee colony, Apis mellifera, and controls reproduction. Queen larvae are selected by the workers and are fed a special diet (royal jelly), which determines caste. Because queens mate with many males a large number of subfamilies coexist in the colony. As a consequence, there is a considerable potential for conflict among the subfamilies over queen rearing. Here we show that honeybee queens are not reared at random but are preferentially reared from rare “royal” subfamilies, which have extremely low frequencies in the colony's worker force but a high frequency in the queens reared.

  9. Accounting for costs, QALYs, and capacity constraints: using discrete-event simulation to evaluate alternative service delivery and organizational scenarios for hospital-based glaucoma services.

    Science.gov (United States)

    Crane, Glenis J; Kymes, Steven M; Hiller, Janet E; Casson, Robert; Martin, Adam; Karnon, Jonathan D

    2013-11-01

    Decision-analytic models are routinely used as a framework for cost-effectiveness analyses of health care services and technologies; however, these models mostly ignore resource constraints. In this study, we use a discrete-event simulation model to inform a cost-effectiveness analysis of alternative options for the organization and delivery of clinical services in the ophthalmology department of a public hospital. The model is novel, given that it represents both disease outcomes and resource constraints in a routine clinical setting. A 5-year discrete-event simulation model representing glaucoma patient services at the Royal Adelaide Hospital (RAH) was implemented and calibrated to patient-level data. The data were sourced from routinely collected waiting and appointment lists, patient record data, and the published literature. Patient-level costs and quality-adjusted life years were estimated for a range of alternative scenarios, including combinations of alternate follow-up times, booking cycles, and treatment pathways. The model shows that a) extending booking cycle length from 4 to 6 months, b) extending follow-up visit times by 2 to 3 months, and c) using laser in preference to medication are more cost-effective than current practice at the RAH eye clinic. The current simulation model provides a useful tool for informing improvements in the organization and delivery of glaucoma services at a local level (e.g., within a hospital), on the basis of expected effects on costs and health outcomes while accounting for current capacity constraints. Our model may be adapted to represent glaucoma services at other hospitals, whereas the general modeling approach could be applied to many other clinical service areas.

  10. Voice work at the Royal Shakespeare Company

    OpenAIRE

    Wade, Andrew

    2007-01-01

    En tant que responsable du département de la voix de la Royal Shakespeare Company, je me dois de démystifier la façon dont nous travaillons avec les acteurs. Il me semble également essentiel de mettre en lumière l’histoire et les objectifs du travail de la RSC sur la voix. Ceci devrait encore clarifier ce que nous entendons par « la voix de Shakespeare ». Depuis de nombreuses années les besoins d’un travail spécifique sur la voix n’ont cessé de grandir avec la compagnie. Cette pratique fait m...

  11. Oral Allergy Syndrome in a Child Provoked by Royal Jelly

    Directory of Open Access Journals (Sweden)

    Fantini Paola

    2014-01-01

    Full Text Available Royal jelly has been demonstrated to have several physiological activities. However, in the literature, different reactions induced by royal jelly are reported. We describe a case of seven-year-old child that was referred to our observation for two episodes of oral allergy syndrome (OAS that appeared ten minutes after ingestion of royal jelly. Skin prick test with standard panel of inhalant and food allergens, a prick-to-prick test using the royal jelly’s extract responsible for patient’s reactions, and royal jelly patch test with extemporaneous preparation were performed. The specific IgE by ImmunoCAP System method versus Hymenoptera venom, inhalant allergens, food allergens, and lipid transfer proteins was dosed. According to the positive reactions to royal jelly both by prick-by-prick test and by a first reading patch test, royal jelly immediate hypersensitivity was diagnosed. According to the positive response for almond in both in vivo and in vitro tests we can think of the royal jelly contamination with almond pollen as possible cause of patient’s reaction. Moreover, from the results of specific IgE titers versus Compositae pollens, we have argued the possibility that this case of royal jelly allergy could be explained also by the mechanism of cross-reaction with Compositae pollens.

  12. The Royal pilgrimage of the Goddess Nanda

    Directory of Open Access Journals (Sweden)

    William S. Sax

    2010-01-01

    Full Text Available Once every twelve years, when it is thought that some calamity has taken place because of the curse of the goddess Nanda Devi, a four-horned ram is born in the fields of the former king of Garhwal, an erstwhile Central Himalayan kingdom in north India (see map of Garhwal. This four-horned ram leads a procession of priests and pilgrims on the most dangerous and spectacular pilgrimage in all of India: a three-week, barefoot journey of one-hundred and sixty-four miles, during some of the worst weather of the year, at the end of the rainy season. The procession reaches Rupkund, a small pond located at an altitude of more than 5,000 metres, which is surrounded by human­ skeletons, and from there it goes yet further, to Homkund, the ‘Lake of the Fire Sacrifice’. According to the faithful, the four-horned ram leaves the procession at that point and finds its way, unaided, to the summit of Mount Trishul. As its name suggests, the Royal Procession is closely associated with the ruler of this erstwhile Himalayan kingdom: he attends its inaugural rituals, the bones that litter the shores of Rupkund are believed to be those of one of his ancestors, and the chief sponsor of the event is a local ‘Prince’ who is thought to be descended from the first kings of Garhwal. This Prince traverses the domain of his ancestors and thereby lays claim to it in the name of the goddess Nanda, who is not only his lineage goddess but was also the royal goddess of the neighbouring kingdom of Kumaon, in pre-colonial times. Although the Royal Procession ideally fosters social integration, it was disrupted in 1987 by a quarrel between two factions of priests. The goddess’s itinerary, the culminating date of the pilgrimage, the type of sacrifice to be performed, the order of procession, the participation of previously excluded persons, and the competency of certain ritual specialists—all were subjects of heated dispute between the rival groups. What was the reason for

  13. NDVI, scale invariance and the modifiable areal unit problem: An assessment of vegetation in the Adelaide Parklands.

    Science.gov (United States)

    Nouri, Hamideh; Anderson, Sharolyn; Sutton, Paul; Beecham, Simon; Nagler, Pamela; Jarchow, Christopher J; Roberts, Dar A

    2017-04-15

    This research addresses the question as to whether or not the Normalised Difference Vegetation Index (NDVI) is scale invariant (i.e. constant over spatial aggregation) for pure pixels of urban vegetation. It has been long recognized that there are issues related to the modifiable areal unit problem (MAUP) pertaining to indices such as NDVI and images at varying spatial resolutions. These issues are relevant to using NDVI values in spatial analyses. We compare two different methods of calculation of a mean NDVI: 1) using pixel values of NDVI within feature/object boundaries and 2) first calculating the mean red and mean near-infrared across all feature pixels and then calculating NDVI. We explore the nature and magnitude of these differences for images taken from two sensors, a 1.24m resolution WorldView-3 and a 0.1m resolution digital aerial image. We apply these methods over an urban park located in the Adelaide Parklands of South Australia. We demonstrate that the MAUP is not an issue for calculation of NDVI within a sensor for pure urban vegetation pixels. This may prove useful for future rule-based monitoring of the ecosystem functioning of green infrastructure. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. The first royal appendix abscess drainage.

    Science.gov (United States)

    Ellis, Harold

    2015-05-01

    On January 22nd 1901, at Osborne House on the Isle of Wight, Queen Victoria, nearing her 82nd birthday and having ruled for 64 years, drew her last breath. Edward Prince of Wales, 59 years of age, was now King Edward VII. A year of mourning was proclaimed and his coronation scheduled for June 26th. It was unexpectedly delayed by an attack of royal appendicitis. On Saturday June 14th 1902, less than two weeks before the coronation, Edward travelled to Aldershot to attend a military review. It was a cold, rainy day and the King did not feel well. That night, his abdominal discomfort was getting worse and by five next morning the King's personal physician, Sir Francis Laking, was called to see him. Laking asked Sir Thomas Barlow, Physician-Extraordinary to the King, for a second opinion. By now there was fever, rigor and distinct tenderness in the right iliac fossa of the very obese abdomen. Under heavy sedation, the King was transferred to Windsor Castle, leaving his Queen, Alexandra, to review the parade of 30,000 soldiers gathered at Aldershot.

  15. Extremity dosimetry trial: Devonport royal dockyard

    International Nuclear Information System (INIS)

    Kenyon, R.; Collison, R.

    2008-01-01

    This trial was undertaken to assess extremity dosemeters, which were made available to Devonport Royal Dockyard and determine the most suitable to the site. The trial included operational and laboratory-based exposures. Operational exposures were within a submarine reactor compartment and a waste storage area. Laboratory exposures were undertaken using 241 Am, 137 Cs and 60 Co sources to compare and contrast the dosemeters energy response. In addition, the low dose response and the response if placed in the incorrect orientation were also assessed. Ten passive and two active dosemeters were tested, with three highlighted as the most technically suitable, DSTL Harshaw DXT-RAD, HPA Harshaw EXT-RAD and the AMEC Panasonic UD-807A. The most technically suitable dosemeter was the DSTL Harshaw DXT-RAD, due to good responses within all aspects of the trial and the user's preference for the ring type design. The John Caunt ED2 electronic dosemeter 2 (ED2) also performed well, but suffered radio frequency interference. (authors)

  16. Royal Wine Corporation d/b/a/ Royal Kedem (Herzog Wine Cellars), Oxnard, CA; Consent Agreement and Final Order

    Science.gov (United States)

    Consent Agreement and Final Order (Proposed CA/FO), between the U.S. Environmental Protection Agency, Region 9 (EPA or Complainant), and Royal Wine Corporation, d/b/a Royal Kedem (Herzog Wine Cellars or Respondent). Docket Number CWA-09-2018-0004.

  17. Principles of Waterfront Renovation to Decisive Spaces for Local Identity: A Study Case of Port Adelaide, South Australia

    Science.gov (United States)

    Taher, S.; Haqi, F. I.

    2017-07-01

    If governments have an objective to participate in a globalized economy, they should address the challenges of blighted inner city and particularly older water front areas. In doing the latter there is often a degree of consistency in place making. While the processes and principles behind urban design and planning need to have an internal logic across different scales to create quality public realms, the outcome of these interventions are frequently unresponsive to regional diversities in culture and identity. This indifference can lead to changes in the built form through urban regeneration activities that do not respect, celebrate or represent the history and traditions of the local community associated with an inner harbour or other forms of urban waterfronts. This research was undertaken to develop a set of design principles for the Inner Harbour renewal project in Port Adelaide, South Australia that would be sensitive to the historical role of the water front and in particular to incorporate the sentiments and needs of long term residents for whom the character of the area and their attachment to it shapes their sense of identity. The research established a theoretical framework for the development of design principles such as functionality, accessibility, natural environment and culture, history and memory. The findings showed that the redevelopment did not significantly disrupt residents’ sense of place or sense of local identity however some more additional design attributes would nevertheless strengthen the capacity of the project to preserve local identity. This paper concludes with recommendations for preserving local identity for residents adjacent to waterfront renewal projects.

  18. Traffic-related air pollution and health co-benefits of alternative transport in Adelaide, South Australia.

    Science.gov (United States)

    Xia, Ting; Nitschke, Monika; Zhang, Ying; Shah, Pushan; Crabb, Shona; Hansen, Alana

    2015-01-01

    Motor vehicle emissions contribute nearly a quarter of the world's energy-related greenhouse gases and cause non-negligible air pollution, primarily in urban areas. Changing people's travel behaviour towards alternative transport is an efficient approach to mitigate harmful environmental impacts caused by a large number of vehicles. Such a strategy also provides an opportunity to gain health co-benefits of improved air quality and enhanced physical activities. This study aimed at quantifying co-benefit effects of alternative transport use in Adelaide, South Australia. We made projections for a business-as-usual scenario for 2030 with alternative transport scenarios. Separate models including air pollution models and comparative risk assessment health models were developed to link alternative transport scenarios with possible environmental and health benefits. In the study region with an estimated population of 1.4 million in 2030, by shifting 40% of vehicle kilometres travelled (VKT) by passenger vehicles to alternative transport, annual average urban PM2.5 would decline by approximately 0.4μg/m(3) compared to business-as-usual, resulting in net health benefits of an estimated 13deaths/year prevented and 118 disability-adjusted life years (DALYs) prevented per year due to improved air quality. Further health benefits would be obtained from improved physical fitness through active transport (508deaths/year prevented, 6569DALYs/year prevented), and changes in traffic injuries (21 deaths and, 960 DALYs prevented). Although uncertainties remain, our findings suggest that significant environmental and health benefits are possible if alternative transport replaces even a relatively small portion of car trips. The results may provide assistance to various government organisations and relevant service providers and promote collaboration in policy-making, city planning and infrastructure establishment. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Parental Midlife Body Shape and Association with Multiple Adult Offspring Obesity Measures: North West Adelaide Health Study.

    Directory of Open Access Journals (Sweden)

    Janet F Grant

    Full Text Available There is compelling evidence that parental weight is a strong determinant of offspring weight status. The study used cross-sectional self-reported and measured data from a longitudinal cohort of Australian adults (n = 2128 from Stage 3 (2008-10 of the North West Adelaide Health Study (1999-2003, baseline n = 4056 to investigate the association between midlife parental body shape and four indicators of obesity and fat distribution. The analysis used measured body mass index (BMI, waist circumference (WC, waist hip ratio (WHR and waist height ratio (WHtR of adult offspring, together with pictograms for recall of parental body shape. Compared to both parents being a healthy weight, offspring were more likely to be overweight or obese if both parents were an unhealthy weight at age 40 (OR 2.14, 95% CI 1.67-2.76 and further, those participants whose mother was an unhealthy weight were more likely to be overweight or obese themselves (OR 1.50, 95% CI 1.14-1.98. There were similar but lower results for those with an overweight/obese father (OR 1.44, 95% CI 1.08-1.93. The effect of one or both parents being overweight or obese tended to be stronger for daughters than for sons across BMI, WC and WHtR. BMI showed the strongest association with parental body shape (OR 2.14, followed by WC (OR 1.78, WHtR (OR 1.71 and WHR (OR 1.45. WHtR (42-45% and BMI (35-36% provided the highest positive predictive values for overweight/obesity from parental body shape. Parental obesity increases the risk of obesity for adult offspring, both for overall body shape and central adiposity, particularly for daughters. Pictograms could potentially be used as a screening tool in primary care settings to promote healthy weight among young adults.

  20. Women's royal holiness as the church-historical phenomenon

    Directory of Open Access Journals (Sweden)

    Efimov Vladimir Fedorovich

    2015-12-01

    Full Text Available The article under the topic of the Royal Holiness examines its specific subtype, the righteousness of the Royal women. Among the saint queens, empresses and princesses the authors distinguish the independent rulers, the widows, and wives of monarchs. The Holy Byzantine Empress and canonized European Queen, the Queen of the Georgian and the Russian Princess defended the Christian statehood brightened by feats of patience, mercy, by building the temples. In the conclusion of the article briefly tells about the Royal martyrs and Confessors of the 20th century.

  1. Nuclear training facilities at the Royal Naval College, Greenwich

    International Nuclear Information System (INIS)

    Head, J.L.; Lowther, C.A.; Marsh, J.R.W.

    1986-01-01

    The paper describes some of the nuclear training facilities at the Royal Naval College and the way the facilities are used in the training of personnel for the Naval nuclear propulsion programme. (author)

  2. [Residency in plastic surgery: comparison between the French and the Canadian Royal College programs].

    Science.gov (United States)

    Sinna, R; Harris, P G; Danino, A M

    2010-02-01

    Learning plastic surgery in Montreal is different from learning plastic surgery in a French university. In Canada, all residency programs are accredited by a national structure: the Royal College of Physicians and Surgeons. We tried to highlight the differences that exist between the French and a North American academic system. With the different rules and law that governs academic education in both countries, we analyzed the following elements: the residency selection, the program of plastic surgery (content and organisation), the system of evaluation and the diplomas. The training of a Canadian plastic surgeon is very controlled. The recommendations of the Royal College guarantee to the resident who enters a program to have the means to acquire a complete training in quantity and in quality. On the four studied items, none is completely similar between both countries. Each having advantages and inconveniences as, for example, the selection of residency by interview or by the classifying national exam. Actually, few French plastic surgery programs could satisfy the requirements of the Royal College on several points, however without failing the training of French plastic surgeons. Nevertheless, we could be inspired by several elements (rotation in private practice,grouping together several academic hospitals. . .) to improve our system of training.

  3. The efficacy of topical Royal Jelly on diabetic foot ulcers healing: A case series

    Directory of Open Access Journals (Sweden)

    Mansour Siavash

    2011-01-01

    Full Text Available Background: Foot ulcers and infections are the major sources of morbidity in individuals with diabetes mellitus. This study aimed to evaluate the efficacy of topical Royal Jelly (a worker honey bee product on healing diabetic foot ulcers. Methods: Diabetic patients with foot ulcers that were referred to our clinic at Khorshid Hospital, Isfahan, Iran; were evaluated three times a week and treated according to standard treatments consisted of offloading, infection control, vascular improvement and debridement if required. In addition, all ulcers were measured and then topical sterile 5% Royal Jelly was applied on the total surface area of the wounds. Eventually, they were covered with sterile dressings. Each patient was followed for a period of three months or until the complete healing. Results: A total of eight patients were enrolled in this study. Of these, two had two ulcers and, therefore, ten ulcers were evaluated. Two ulcers were excluded. Seven of the remained eight ulcers healed. Mean duration of complete healing was 41 days. One ulcer did not completely heal but improved to 40% smaller in length, 32% in width and 28% in depth. The mean length, width and depth reduction rates were 0.35 mm/day, 0.28 mm/day and 0.11 mm/day, respectively. Conclusions: Royal Jelly dressing may be an effective method for treating diabetic foot ulcers besides standard treatments.

  4. Preventing falls in hospital.

    Science.gov (United States)

    Pearce, Lynne

    2017-02-27

    Essential facts Falls are the most frequent adverse event reported in hospitals, usually affecting older patients. Every year, more than 240,000 falls are reported in acute hospitals and mental health trusts in England and Wales, equivalent to more than 600 a day, according to the Royal College of Physicians (RCP). But research shows that when nurses, doctors and therapists work together, falls can be reduced by 20-30%.

  5. Physicochemical composition of pure and adulterated royal jelly

    Directory of Open Access Journals (Sweden)

    Luis Henrique Garcia-Amoedo

    2007-04-01

    Full Text Available The physicochemical composition of pure royal jelly as well as of some adulterated samples was analyzed by determining moisture, ash, lipids, nitrogen/proteins, carbohydrates, starch and 10- HDA (10-hydroxy-2-decenoic acid. The solubility in alkaline medium was used to detect the main frauds for adulterating royal jelly which comprise addition of yogurt, water, egg white, sweet condensed milk mixed with propolis, unripe banana and corn starch slurry.

  6. Kesejahteraan Karyawan PT. Royal Coconut Kabupaten Minahasa Utara

    OpenAIRE

    Londa, Very Y; Kaunang, Markus; Karim, Dian Fitriani

    2015-01-01

    Employee welfare is a form of welfare services provided by the company to the employees who have given power, mind and their services. Company Parties have an obligation to make efforts to motivate employees to provide benefits that can improve employee productivity. Welfare programs provided by the company to employees of PT. Royal Coconut North Minahasa yet either. Using qualitative methodology, research results show that the well-being of employees is not a good idea due to the PT. Royal C...

  7. Recovering the royal cuisine in Chosun Dynasty and its esthetics

    Directory of Open Access Journals (Sweden)

    Hae-Kyung Chung

    2017-12-01

    Full Text Available We believe that researching the cuisine consumed by the royal family, in particular the king, during the 500-year long Chosun Dynasty is an interesting and meaningful endeavor. This task is an important part of unraveling the cultural significance of Korean cuisine in the 21st century, a new age of gastronomy. Until now, research has largely focused on recreating Chosun royal cuisine based on oral statements from staff in the last royal kitchen or the Uikwe (儀軌, the Royal Protocols which recorded food consumed at banquets. However, little research has been conducted on ordinary royal cuisine consumed by the king, mainly because of a lack of materials to study. This article aims to shed light on this topic and recreate what every day royal cuisine looked like in the late stages of the Chosun Dynasty by examining joseoksangsikbalgi (朝夕上食撥記, memos of morning and evening ancestral rites table and judaryebalgi (晝茶禮撥記, memos of daytime tea ceremonies. The memos are similar to the chanpumdanja (饌品單子, literally meaning “a list of dishes served on the table” that recorded national banquets and therefore do not contain records of ordinary royal cuisine. However, the memos of morning and evening ancestral rites table still remain. These documents describe food offered to the deceased, which was the same as the meals they regularly ate while alive. Accordingly, we attempted to reproduce the traditional table setting for ordinary royal cuisine served to King Kojong (高宗 by analyzing these memos. King Kojong (1852–1919 was the 26th king of the Chosun Dynasty, and a detailed description of the sangsik (上食, ancestral rites table prepared following his death in January 1919 is present in the morning and evening sangsik memos and daytime tea ceremony memos from October 11, 1919. After analyzing the memos from after King Kojong's death in 1919, we were able to determine that the cuisine consisted of rice as bap (a

  8. Effect of different levels of royal jelly on biochemical parameters of ...

    African Journals Online (AJOL)

    Administrator

    2011-09-12

    Sep 12, 2011 ... treatment of cancer, atherosclerosis, hypertension, infertility, asthma, depression and ... and body composition was determined by Tanita BC 418 MA. Royal jelly. Royal jelly used in the study was ... acids content of royal jelly. The composition of the royal jelly used in the study was determined. Saritaş et al.

  9. Royal Wine Corporation d/b/a/ Royal Kedem (Herzog Wine Cellars), Oxnard, CA; Proposed Settlement of Clean Water Act Class II Administrative Penalty and Opportunity to Comment

    Science.gov (United States)

    Public Notice of Proposed Settlement of Clean Water Act Class II Administrative Penalty and Opportunity to Comment In the Matter of Royal Wine Corporation d/b/a/ Royal Kedem (Herzog Wine Cellars), Oxnard, California.

  10. The Accounting Register of a Royal Secretary in Aragonese Naples

    Directory of Open Access Journals (Sweden)

    Enza Russo

    2013-04-01

    Full Text Available In the crucial years of the succession war that involved the Kingdom of Naples after Alfonso the Magnanimous’death (1459-1464, a secretary of the new king Ferrante I of Aragon, Antonello Petrucci, was entrusted with royal financial charges. He therefore compiled an account book, where receipts and payments of the royal finances were carefully recorded. It has been recently discovered: this paper aims at examining its actual framework as well as the relative volume of the state budget. Because of its new and comprehensive body of evidence, Petrucci’s account book is a very useful source, which may provide additional informations not only on the bulk of the state funds and expenditure but also on the structure of the king’s household and on the system of the royal financial administration, which appears now as characterized by a more complex organization than it was supposed to be in the past.

  11. Octanoic acid confers to royal jelly varroa-repellent properties

    Science.gov (United States)

    Nazzi, Francesco; Bortolomeazzi, Renzo; Della Vedova, Giorgio; Del Piccolo, Fabio; Annoscia, Desiderato; Milani, Norberto

    2009-02-01

    The mite Varroa destructor Anderson & Trueman is a parasite of the honeybee Apis mellifera L. and represents a major threat for apiculture in the Western world. Reproduction takes place only inside bee brood cells that are invaded just before sealing; drone cells are preferred over worker cells, whereas queen cells are not normally invaded. Lower incidence of mites in queen cells is at least partly due to the deterrent activity of royal jelly. In this study, the repellent properties of royal jelly were investigated using a lab bioassay. Chemical analysis showed that octanoic acid is a major volatile component of royal jelly; by contrast, the concentration is much lower in drone and worker larval food. Bioassays, carried out under lab conditions, demonstrated that octanoic acid is repellent to the mite. Field studies in bee colonies confirmed that the compound may interfere with the process of cell invasion by the mite.

  12. Royal Order of 5 December 1975 amending the Royal Order of 11 May 1971 embodying the general Military Regulations for Protection Against the Hazards of Ionizing Radiations

    International Nuclear Information System (INIS)

    1975-01-01

    This Royal Order amends the Royal Order on general Military Regulations for Protection against the Hazards of Ionizing Radiations to bring it into line with the Royal Order of 23 December 1970, amending the general Regulations for Protection of the Population and Workers against the Hazards of Ionizing Radiations of 28 February 1963, subject to certain adaptations specific to military activities. (NEA) [fr

  13. Magnetic resonance imaging: project planning and management of a superconductive M.R.I. installation

    International Nuclear Information System (INIS)

    Condon, P.M.; Robertson, A.R.

    1989-01-01

    The planning and installation of a Superconductive Magnetic Resonance Imaging installation at the Royal Adelaide Hospital, Adelaide, South Australia is described. Tender specification, assessment of offers via criteria weighted analysis of technical and economic factors and the final recommendation for a 1.0 Tesla unit are discussed. Building and installation considerations are noted including fringe field effects, magnetic shielding, radiofrequency shielding, cryogens, metallic screening and specific considerations in the Magnet room. 9 refs., 7 figs

  14. The British Royal Family’s Circumcision Tradition

    Directory of Open Access Journals (Sweden)

    Robert Darby

    2013-10-01

    Full Text Available The birth of Prince William’s son in July 2013 was the occasion for an outpouring of media speculation about the fate of the royal baby’s foreskin. The possibility that he might be circumcised was connected to a purported tradition of circumcision within the British royal family, said to be have been initiated either by Queen Victoria or by George I. In this article, we trace the origins and evolution of these stories and assess their validity. Our conclusion is that belief in a royal circumcision tradition derives from the reported circumcision of Prince Charles by the mohel Jacob Snowman in 1948, and the efforts of the British Israelite movement to concoct a “lost tribes of Israel” origin for the British race. These elements merged into a fully developed narrative that was widely disseminated from the late 1990s. The initially separate claim that the tradition was imported from Hanover by George I can be sourced precisely to 2012. We further show that these stories are inventions, and that the royal family circumcision tradition should be regarded as a classic instance of a contemporary legend or urban myth.

  15. Re-engineering production systems: the Royal Netherlands Naval Dockyard

    NARCIS (Netherlands)

    Zijm, Willem H.M.

    1996-01-01

    Reengineering production systems in an attempt to meet tight cost, quality and leadtime standards has received considerable attention in the last decade. In this paper, we discuss the reengineering process at the Royal Netherlands Naval Dockyard. The process starts with a characterisation and a

  16. Royal Numico N.V. : Resurrecting shareholder value

    NARCIS (Netherlands)

    Lachotzki, F.; Olson, M.A.

    2008-01-01

    This case presents the extraordinary turn-around engineered at Royal Numico (a specialized nutrition company, previously covered in another Nyenrode case under its old name Nutricia) by a team of managers formed and led by Jan Bennink. Company fortunes were at a low ebb by the beginning of 2002, as

  17. Efficacy of royal jelly on methotrexate-induced systemic oxidative ...

    African Journals Online (AJOL)

    The aim of this present study is to investigate the mucositis caused by methotrexate (MTX), as well as whether the application of royal jelly (RJ) has a protective effect on oxidative stress. This present study included six groups each consisted of 12 Wistar rats. Distilled water (po: peroral) was given to the 1st group as placebo ...

  18. Evaluation of the antioxidant potential of royal jelly during storage

    Directory of Open Access Journals (Sweden)

    Renata Galhardo Borguini

    2012-09-01

    Full Text Available Royal jelly is a creamy substance produced by young nurse worker bees, which has a color that ranges from white to slightly yellow, and is secreted by the hypopharingeal and mandibular glands of the bees. The objective of this work was to assess the in vitro antioxidant potential of royal jelly while in storage. The physical-chemical parameters analyzed were moisture, ascorbic acid and total phenolic content. Alcohol extracts were made and used to evaluate the 1.1-diphenyl-2-picrylhydrazyl (DPPH radical scavenging activity. The ascorbic acid (to 0.75 from 1.31mg.100g-1wet base and total phenolic content (to 14.26 from 28.30mg GAE.100g-1 wet base of the royal jelly were low. The percentages of DPPH discoloration of the samples were above 50%, except for the samples stored for 90 days. Considering the reduced ascorbic acid and total phenolic content, and the low alcohol DPPH scavenging activity of the samples, it can be concluded that royal jelly presents relatively low antioxidant potential. The storage time did not determine the changes found.

  19. [Nahabed Roussignan, the first professor of deontology at the Royal School of Medicine].

    Science.gov (United States)

    Yildirim, N

    1995-01-01

    This study based on researches utilizing the American and Ottoman sources, deals with the claim upon the lectures given by Roussignan (Rusinyan Efendi), especially at the Royal School of Medicine and describes his medical career as follows. Nahabed Roussignan who graduated from Paris School of Medicine in 1849, returned to Istanbul in 1851 and was appointed as the private physician to Fuad Pasha, upon the request of Dr. Serviçen. In the meantime he worked at the Bab-i Seraskeri Hastanesi (the Hospital of the Military Ministry) until 1860 and also started to work at the Military High School as a doctor of medicine. As to the Royal School of Medicine, he taught pathological anatomy between 1864-1872. There are not any records to prove his being a faculty member during this year. He was probably in financial shortage because of unemployment during that year, as stated by Artin Mezbour. The following year he was employed at in the School of Medicine again, through his friends' support. this time he taught logic and French composition between 1874-1876 and instructed deontology for a little while in 1876. He collected his lectures on logic as a Textbook of Philosophy. He passed away in the same week, so this book was published posthumously (Istanbul 1879). Since he died on November 29th 1876, at the end of the year, his name was included in the State Yearbook of 1877, but was misspelled as "Rüsteban". To sum up, deontology as an independant discipline at the Royal School of Medicine began to be lectured for the first time by N. Roussignan in 1876, and succeeding his death these lectures were taken over by Dr. Hovsep Nouridjan (Nurican Efendi). Istepan Arslanian, who was claimed to be the lecturer of these courses after Roussignan, was in Rumelie during 1875-1876 and employed in Austria in 1877; therefore he could never have taught deontology during this period.

  20. Was an epidemic of gonorrhoea among heterosexuals attending an Adelaide sexual health services associated with variations in sex work policing policy?

    Science.gov (United States)

    Li, Bin; Bi, Peng; Waddell, Russell; Chow, Eric Pf; Donovan, Basil; McNulty, Anna; Fehler, Glenda; Loff, Bebe; Shahkhan, Hana; Fairley, Christopher K

    2016-08-01

    A review of historical trends in gonococcal diagnoses made at the Adelaide Sexual Health Clinic (ASHC), South Australia, identified a substantial rise in diagnoses among heterosexuals between 2006 and 2010. Sex work is illegal in South Australia, regulated in Victoria and legal in New South Wales. This and other factors that could have influenced the epidemic were explored in this analysis. Retrospective analyses of gonorrhoea diagnoses made by sexual health services between 1990 and 2012 in three Australian state capitals, Melbourne (Victoria) and Sydney (New South Wales) were undertaken. At the ASHC the proportion of gonorrhoea diagnoses was higher between 2006 and 2010 among heterosexual men (5.34% vs 0.84%, p<0.001), non-sex worker women (0.64% vs 0.28%, p<0.001) and female sex workers (FSWs) (1.75% vs 0.24%, p<0.001) compared with other years. This relationship was not seen at the Melbourne Sexual Health Clinic and corresponding data from the Sydney Sexual Health Centre showed that FSWs were less likely to have gonorrhoea between 2006 and 2010 than the other groups (p=0.746, p=0.522, p=0.024, respectively). At ASHC FSWs were significantly more likely to be diagnosed between 2006 and 2010 (OR 2.8, 95% CI 1.48 to 5.27, p=0.002). Charges against sex workers peaked in 2007/2008. A substantial, self-limiting rise in diagnoses of heterosexual gonorrhoea was seen in Adelaide FSWs between 2006 and 2010. Removing barriers to condom use is vital to the prevention of HIV and STI transmission. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  1. Royal Order of 23 November 1977 amending the Royal order of 12 December 1975 setting up a National Energy Committee

    International Nuclear Information System (INIS)

    1978-01-01

    Royal Order of 23 November 1977 modified the composition of the National Energy Committee. Members of delegations are appointed by the Minister for Economic Affairs for a 5-year period which is renewable. The Secretariat includes members recognised for their technical, economic or social competence in the energy field. (NEA) [fr

  2. Hospital management structures in Maltese hospital through the ages

    OpenAIRE

    Savona-Ventura, Charles

    2001-01-01

    The spreading cult of Christ the Healer during the Medieval period led to sick-nursing being viewed as a Christian duty. This encouraged royal dignitaries and philantrophic individuals to donate funds towards the institution and maintenance of a hospital or hospice, the management of these institutions being often shared with religious authorities. The Maltese Islands have been serviced by a series of hospitals, the earliest dating to the fourteenth century. In line with the ch...

  3. [In the era of the Royal Society of Medicine].

    Science.gov (United States)

    Gramain, Pascale

    2013-01-01

    In the May 2013 issue of medecine/sciences, the Rob Laffecteur complained about the constraints imposed by the Société Royale de Médecine in 1779, bearing on the labelling of remedies. Though, he did take advantage of the evaluation from an advertising point of view; though in this prospect he diverted his evaluation's report, in order to present it in a flattering manner. The Société Royale de Médecine was founded in 1778; its mission was to cover everything that had to do with public healthcare. Active, age-old and competent, it was submitted to many of contemporary issues that we are facing nowadays in the matter of medicines' evaluation, which is based on a rigorous scientific evaluation, itself based on knowledge's state-of-the-art. © 2013 médecine/sciences – Inserm.

  4. The Royal College of Psychiatrists and the death penalty.

    Science.gov (United States)

    Gunn, John

    2004-01-01

    The Royal College of Psychiatrists recently issued a revised statement on its position concerning capital punishment. The College proposes to support psychiatrists who refuse to be involved in the capital process, but accepts that some may take up limited involvement in the manner set out in the document. The Royal College is the professional body for psychiatric practitioners in the United Kingdom and Ireland. Almost no public statements are issued from the College without first being deliberated on within at least two of its three major committees. The new document on capital punishment remains in the spirit of the previous ones. The topic of capital punishment is noncontroversial within the British medical profession. In all European countries, capital punishment is against the law, because there is an overarching directive from the Council of Europe (a wide group of nations, wider than the European Union) insisting that it be abolished.

  5. The Magnetic Observatory Buildings at the Royal Observatory, Cape

    Science.gov (United States)

    Glass, I. S.

    2015-10-01

    During the 1830s there arose a strong international movement, promoted by Carl Friedrich Gauss and Alexander von Humboldt, to characterise the earth's magnetic field. By 1839 the Royal Society in London, driven by Edward Sabine, had organised a "Magnetic Crusade" - the establishment of a series of magnetic and meteorological observatories around the British Empire, including New Zealand, Australia, St Helena and the Cape. This article outlines the history of the latter installation, its buildings and what became of them.

  6. The Ursula Faince Dinnerware Series by Royal Copenhagen

    DEFF Research Database (Denmark)

    Moeran, Brian

    This working paper is a case study about the development of a faience product line in Royal Copenhagen and illustrates several aspects of how, at what stages of development, and by whom, cultural products in general are evaluated. Three theoretical issues emerge. One concerns the constraints impo...... of a particular cultural product had to be negotiated within a particular organizational world embracing both management and workers, with differentiated skills. These issues lead to a more general discussion of craftsmanship and storytelling....

  7. Je Maintiendrai: The Royal Netherlands Army Within the Alliance

    Science.gov (United States)

    1989-06-01

    CHAPTER I Combat History of the Dutch Army The Kir.ngdom of the Netherlands has tended to favor neutrality or abstentionism over involvement in...a small power and the Dutch increasingly favored abstentionism from European conflicts. Subsequently, the wartime organization of the Royal Army was...Netherlands abandoned its traditional policy of abstentionism and became a founding member of the Brussels Treaty (1948) and the North Atlantic

  8. Gambling in revolutionary Paris - The Palais Royal: 1789-1838.

    Science.gov (United States)

    Barnhart, R T

    1992-06-01

    By the revolution of 1789, the four-story, quadrangular Palais Royal in Paris had become the most glittering tourist center of Europe, with 180 shops and cafes in its ground floor arcades. By 1791, its basement and secondary story contained over 100 separate, illicit gambling operations featuring the most popular dice and card games. The mania for gambling had been transferred from defunct, monarchical Versailles to the thriving, bourgeois Palais Royal, where the five main gaming clubs throbbed from noon till midnight. During the Revolution, Prince Talleyrand won 30,000 francs at one club, and after Waterloo in 1815, Marshal Blucher lost 1,500,000 francs in one night at another. To bring the situation under control and raise taxes for the state, in 1806 Napoleon legalized the main clubs, which from 1819 to 1837 grossed an enormous 137 million francs. When the anti-gambling forces triumphed in 1837 and the clubs were closed down, the National Guard had to be called out to evict the mobs of gamblers who refused to leave the tables. Dramatic reports from Revolutionary police raids, and quotations from the memoirs of humorous French gamblers and shocked foreign visitors, provide anecdotal illustrations of the 49 years during which the Palais Royal was the most intriguing and picturesque gambling mecca of Europe-and probably of the world.

  9. Secondary postpartum haemorrhage - a underappreciated danger. A retrospective review of the incidence of hysterectomy for the 37 years at Holles St Hospital

    LENUS (Irish Health Repository)

    2011-02-01

    Institute of Obstetricians & Gynaecologists, RCPI Four Provinces Meeting, Junior Obstetrics & Gynaecology Society Annual Scientific Meeting, Royal Academy of Medicine in Ireland Dublin Maternity Hospitals Reports Meeting, Nov 2010

  10. The geologic story of Isle Royale National Park

    Science.gov (United States)

    Huber, N. King

    1975-01-01

    Isle Royale is an outstanding example of relatively undisturbed northwoods lake wilderness. But more than simple preservation of such an environment is involved in its inclusion in our National Park System. Its isolation from the mainland provides an almost untouched laboratory for research in the natural sciences, especially those studies whose very nature depends upon such isolation. One excellent example of such research is the intensive study of the predator-prey relationship of the timber wolf and moose, long sponsored by the National Park Service and Purdue University. In probably no other place in North America are the necessary ecological conditions for such a study so admirably fulfilled as on Isle Royale. The development of a natural laboratory with such conditions is ultimately dependent upon geologic processes and events that although not unique in themselves, produced in their interplay a unique result, the island archipelago as we know it today, with its hills and valleys, swamps and bogs the ecological framework of the plant and animal world. Even the most casual visitor can hardly fail to be struck by the fiordlike nature of many of the bays, the chains of fringing islands, the ridge-and-valley topography, and the linear nature of all these features. The distinctive topography of the archipelago is, of course, only the latest manifestation of geologic processes in operation since time immemorial. Fragments of geologic history going back over a billion years can be read from the rocks of the island, and with additional data from other parts of the Lake Superior region, we can fill in some of the story of Isle Royale. After more than a hundred years of study by man, the story is still incomplete. But then, geologic stories are seldom complete, and what we do know allows a deeper appreciation of one of our most naturally preserved parks and whets our curiosity about the missing fragments.

  11. Visit of Her Royal Highness Princess Maha Chakri Sirindhorn, Thailand

    CERN Multimedia

    Patrice Loïez

    2000-01-01

    Her Royal Highness Princess Maha Chakri Sirindhorn of Thailand (left) visiting DELPHI with Spokesman, Tiziano Camporesi, and Prapol Assavavirulhakarn, Pattaratorn Chirapravati, Claude Détraz, CERN Director for Fixed Target andFuture Programmes and Richard Breedon, University of California. No. 05: Princess Maha Chakri Sirindhorn and Daniel Treille, former spokesman of Delphi. No. 31: in Delphi experiment. No. 35: H.E. Mr. Virasakdi Futrakul, Ambassador, Permanent Representative ofThailand, Geneva with H.E. Dr. Ronarong Nopakun, Ambassador of the Thai Embassy in Bern

  12. Mycelium characterization of the Amauroderma sp collected from Royal Belum

    International Nuclear Information System (INIS)

    Hassan Hamdani Mutaat; Mat Rasol Awang; Fauzi Daud; Rosnani Rashid; Meswan Maskom; Arfah Sumeri

    2010-01-01

    Etnobotanical study carried on the native community in the Royal Belum Forest areas had identified many potentially valuable spices that could be further explored for its medicinal and health purposes. The mushrooms, Amauroderma sp. was one of the resources that had been screened and collected for further investigation. In this works, the mycelium characterization of the mushroom was carried out in order to develop suitable seed or spawn for cultivation. The Amauroderma sp. mycelium, cultured from the fruit body tissue was found to grow well on the PDA plate. While on the potato extract liquid medium the mushroom could grow and produce stalk like fruit body. (author)

  13. Background submission to the Royal Commission on Nuclear Power Generation

    International Nuclear Information System (INIS)

    1976-12-01

    The Royal Commission on Nuclear Power Generation in New Zealand is required to inquire into and report upon the likely consequences of a nuclear power programme. The New Zealand Electricity Department would have prime responsibilty for implementing the construction, operation and maintenance of nuclear power plants should the need be established and should this be acceptable to the Government. In this submission the Department has attempted to present the issues raised by the introduction of nuclear power in relatively simple terms on the assumption that elaboration can be provided later if necessary

  14. Royal Ageing: The Queen Mother and Queen Victoria

    OpenAIRE

    Mike Hepworth

    2002-01-01

    This paper is a reflection on the contribution of the image of the Queen Mother to the cultural construction of role models of positive ageing. The interest lies in the Queen Mother's performance in public of her roles as woman and royal personage particularly as she grew older. It is suggested that cultural analysis of the icon of the Queen Mother as a blend of gender and power suggests certain significant parallels with the imagery cultivated around the career of Queen Victoria in the later...

  15. The ratio of ICRP103 to ICRP60 calculated effective doses from CT: Monte Carlo calculations with the ADELAIDE voxel paediatric model and comparisons with published values

    International Nuclear Information System (INIS)

    Caon, Martin

    2013-01-01

    The ADELAIDE voxel model of paediatric anatomy was used with the EGSnrc Monte Carlo code to compare effective dose from computed tomography (CT) calculated with both the ICRP103 and ICRP60 definitions which are different in their tissue weighting factors and in the included tissues. The new tissue weighting factors resulted in a lower effective dose for pelvis CT (than if calculated using ICRP60 tissue weighting factors), by 6.5 % but higher effective doses for all other examinations. ICRP103 calculated effective dose for CT abdomen + pelvis was higher by 4.6 %, for CT abdomen (by 9.5 %), for CT chest + abdomen + pelvis (by 6 %), for CT chest + abdomen (by 9.6 %), for CT chest (by 10.1 %) and for cardiac CT (by 11.5 %). These values, along with published values of effective dose from CT that were calculated for both sets of tissue weighting factors were used to determine single values for the ratio ICRP103:ICRP60 calculated effective doses from CT, for seven CT examinations. The following values for ICRP103:ICRP60 are suggested for use to convert ICRP60 calculated effective dose to ICRP103 calculated effective dose for the following CT examinations: Pelvis CT, 0.75; for abdomen CT, abdomen + pelvis CT, chest + abdomen + pelvis CT, 1.00; for chest + abdomen CT, and for chest CT. 1.15; for cardiac CT 1.25.

  16. Report from the Biennial Scientific Meeting of the Australasian Section of the American Oil Chemists Society (AAOCS Held in Adelaide, November 2011

    Directory of Open Access Journals (Sweden)

    Matthew R. Miller

    2012-05-01

    Full Text Available The Australasian section of the American Oil Chemists Society (AAOCS held their biennial meeting in Adelaide, Australia on 8–11 November 2011. Over 70 scientists, researchers and industry representatives gathered for three days of talks and discussions on lipid related topics. A highlight was the hot topic symposium on the new olive oil standard being introduced in Australia. Paul Miller, Australian Olives Association, gave a compelling address on why the standard was needed. He demonstrated that the increase in price and demand for high quality olive oils has led to products falsely or misleadingly labelled. Furthermore, the genetic and seasonal variation in minor components of olive oil has led to misclassifications. An extensive scientific and political process in Australia and overseas led to development of this new standard. Dr. Leandro Ravetti, Mordern Olives, demonstrated the development of two new methods, for analysis of pyropheophytins and diacylglycerols, are good indicators of modification by deodorisation of oils and show excellent correlation with organoleptic assessment with aging/degradation of extra virgin olive oils. Professor Rod Mailer finished this session with studies of actual adulteration cases in Australia and overseas, further highlighting the need for this new standard. [...

  17. Estudo da adaptação e aplicabilidade do questionário perfil de atividades de Adelaide em idosos de uma comunidade Nipo-Brasileira Adaptation and applicability of the Adelaide activities profile for older adults of a community of Japanese origin

    Directory of Open Access Journals (Sweden)

    Miriam Masako Kanashiro

    2011-01-01

    Full Text Available O envelhecimento ativo está associado ao bem-estar e qualidade de vida. Este estudo de corte transversal teve o propósito de adaptar e analisar a aplicabilidade do questionário Perfil de Atividades de Adelaide (PAA, no Brasil e caracterizar a frequência e perfil de atividades de idosos pertencentes à cultura Japonesa. O questionário PAA foi traduzido e adaptado para o português do Brasil. A amostra foi composta por dois grupos: 30 praticantes do jogo mahjong e 30 praticantes do esporte gateball, de ambos os sexos. Observou-se que as mulheres foram mais ativas nos domínios serviço doméstico, serviço para outros, e lazer intelectual, os homens, em atividades sociais. O PAA pode ser útil para analisar o perfil da prática de atividades entre idosos e orientar a indicação de intervenções gerontológicas.Active aging is associated with well-being and quality of life. The aim of this cross-sectional study was to adapt and analyze the applicability of the Adelaide Activities Profile (AAP in Brazil, and characterize the frequency and type of activities carried out by older adults who belong to the Japanese community. The questionnaire was translated and adapted to Brazilian Portuguese. The sample was composed by two groups: 30 mahjong players and 30 gateball players, men and women. Women were more active in domestic chores, service to others, and intellectual leisure; men were more active in social activities. The AAP may be useful to analyze the activity profile of older adults and guide the indication of gerontological interventions.

  18. Violence toward health workers in Bahrain Defense Force Royal Medical Services’ emergency department

    Directory of Open Access Journals (Sweden)

    Rafeea F

    2017-11-01

    Full Text Available Faisal Rafeea,1 Ahmed Al Ansari,2–4 Ehab M Abbas,1 Khalifa Elmusharaf,5 Mohamed S Abu Zeid1 1Emergency Department, Bahrain Defense Force Hospital, Riffa, Bahrain; 2Training and Education Department, Bahrain Defense Force Hospital, Riffa, Bahrain; 3Department of General Surgery, College of Medicine and Medical Science, Arabian Gulf University, Manama, Bahrain; 4Medical Education Department, Royal College of Surgeons in Ireland - Medical University of Bahrain, Busaiteen, Bahrain; 5Graduate Entry Medical School, University of Limerick, Ireland Background: Employees working in emergency departments (EDs in hospital settings are disproportionately affected by workplace violence as compared to those working in other departments. Such violence results in minor or major injury to these workers. In other cases, it leads to physical disability, reduced job performance, and eventually a nonconducive working environment for these workers. Materials and methods: A cross-sectional exploratory questionnaire was used to collect data used for the examination of the incidents of violence in the workplace. This study was carried out at the ED of the Bahrain Defense Force (BDF Hospital. Participants for the study were drawn from nurses, support staff, and emergency physicians. Both male and female workers were surveyed.Results: The study included responses from 100 staff in the ED of the BDF Hospital in Bahrain (doctors, nurses, and support personnel. The most experienced type of violence in the workers in the past 12 months in this study was verbal abuse, which was experienced by 78% of the participants, which was followed by physical abuse (11% and then sexual abuse (3%. Many cases of violence against ED workers occurred during night shifts (53%, while physical abuse was reported to occur during all the shifts; 40% of the staff in the ED of the hospital were not aware of the policies against workplace violence, and 26% of the staff considered leaving their jobs

  19. Occupational stress and strain in the Royal Navy 2007.

    Science.gov (United States)

    Bridger, R S; Brasher, K; Dew, A; Kilminster, S

    2008-12-01

    Previous surveys of psychological strain in the Naval Service (NS) have shown higher than expected levels of strain when compared to the general population. To repeat the survey last carried out in 2004 and to obtain further information on the nature of the occupational stressors associated with strain. General Health Questionnaire-12 strain rates and job/life stressors were measured using a Work and Well-Being Questionnaire. Models of strain were developed for male and female personnel in the Royal Navy (RN) and males in the Royal Marines (RM). The response rate was 57%. The psychological strain rate was 31.5% overall. Personnel suffering from strain tended to be 'overcommitted' to work, had low levels of commitment to the NS and had suffered stressful life events (SLEs) in the previous 12 months. Strain rates declined with age and rank in males, but not in females. Strain was significantly positively correlated with levels of overcommitment, effort-reward imbalance (ERI), role conflict, work-family conflict, organizational commitment and exposure to SLEs. Models of strain in the males and females in the RN and in the RM accounted for between 37 and 44% of the variance in strain. The survey provides evidence for both the demand control and ERI models-components of these models contribute independently to strain. High levels of commitment to the organization were associated with lower strain and exposure to SLEs to higher strain.

  20. Royal Society Scientific Meeting: Extracellular vesicles in the tumour microenvironment.

    Science.gov (United States)

    Pink, Ryan Charles; Elmusrati, Areeg A; Lambert, Daniel; Carter, David Raul Francisco

    2018-01-05

    Cancer cells do not grow as an isolated homogeneous mass; tumours are, in fact, complex and heterogeneous collections of cancer and surrounding stromal cells, collectively termed the tumour microenvironment. The interaction between cancer cells and stromal cells in the tumour microenvironment has emerged as a key concept in the regulation of cancer progression. Understanding the intercellular dialogue in the tumour microenvironment is therefore an important goal. One aspect of this dialogue that has not been appreciated until recently is the role of extracellular vesicles (EVs). EVs are small vesicles released by cells under both normal and pathological conditions; they can transfer biological molecules between cells leading to changes in phenotype. EVs have emerged as important regulators of biological processes and can be dysregulated in diseases such as cancer; rapidly growing interest in their biology and therapeutic potential led to the Royal Society hosting a Scientific Meeting to explore the roles of EVs in the tumour microenvironment. This cross-disciplinary meeting explored examples of how aberrant crosstalk between tumour and stromal cells can promote cancer progression, and how such signalling can be targeted for diagnostic, prognostic and therapeutic benefit. In this review, and the special edition of Philosophical Transactions of the Royal Society B that follows, we will provide an overview of the content and outcomes of this exciting meeting.This article is part of the discussion meeting issue 'Extracellular vesicles and the tumour microenvironment'. © 2017 The Author(s).

  1. Retrospective Analysis of Patient Presentations at the Sydney (Australia) Royal Easter Show from 2012 to 2014.

    Science.gov (United States)

    Crabtree, Nathan; Mo, Shirley; Ong, Leon; Jegathees, Thuvarahan; Wei, Daniel; Fahey, David; Liu, Jia Jenny

    2017-04-01

    Introduction Comprehensive studies on the relationship between patient demographics and subsequent treatment and disposition at a single mass-gathering event are lacking. The Sydney Royal Easter Show (SRES; Sydney Olympic Park, New South Wales, Australia) is an annual, 14-day, agricultural mass-gathering event occurring around the Easter weekend, attracting more than 800,000 patrons per year. In this study, patient records from the SRES were analyzed to examine relationships between weather, crowd size, day of week, and demographics on treatment and disposition. This information would help to predict factors affecting patient treatment and disposition to guide ongoing training of first responders and to evaluate the appropriateness of staffing skills mix at future events. Hypothesis Patient demographics, environmental factors, and attendance would influence the nature and severity of presentations at the SRES, which would influence staffing requirements. A retrospective analysis of 4,141 patient record forms was performed for patients who presented to St John Ambulance (Australian Capital Territory, Australia) at the SRES between 2012 and 2014 inclusive. Presentation type was classified using a previously published minimum data set. Data on weather and crowd size were obtained from the Australian Bureau of Meteorology (Melbourne, Victoria, Australia) and the SRES, respectively. Statistical analyses were performed using SPSS v22 (IBM; Armonk, New York USA). Between 2012 to 2014, over 2.5 million people attended the SRES with 4,141 patients treated onsite. As expected, the majority of presentations were injuries (49%) and illnesses (46%). Although patient demographics and presentation types did not change over time, the duration of treatment increased. A higher proportion of patients were discharged to hospital or home compared to the proportion of patients discharged back to the event. Patients from rural/regional locations (accounting for 15% of all patients) were

  2. The Royal College of Radiologists Breast Group breast imaging classification

    International Nuclear Information System (INIS)

    Maxwell, A.J.; Ridley, N.T.; Rubin, G.; Wallis, M.G.; Gilbert, F.J.; Michell, M.J.

    2009-01-01

    Standardisation of the classification of breast imaging reports will improve communication between the referrer and the radiologist and avoid ambiguity, which may otherwise lead to mismanagement of patients. Following wide consultation, Royal College of Radiologists Breast Group has produced a scoring system for the classification of breast imaging. This will facilitate audit and the development of nationally agreed standards for the investigation of women with breast disease. This five-point system is as follows: 1, normal; 2, benign findings; 3, indeterminate/probably benign findings; 4, findings suspicious of malignancy; 5, findings highly suspicious of malignancy. It is recommended that this be used in the reporting of all breast imaging examinations in the UK.

  3. Hearing loss in the Royal Norwegian Navy: A longitudinal study.

    Science.gov (United States)

    Irgens-Hansen, Kaja; Baste, Valborg; Bråtveit, Magne; Lind, Ola; Koefoed, Vilhelm F; Moen, Bente E

    2016-01-01

    The aims of this longitudinal study were to investigate a significant threshold shift (STS) among personnel working on board the Royal Norwegian Navy's (RNoN) vessels between 2012 and 2014 and to identify possible determinants of STS. Hearing thresholds were measured by pure tone audiometry in two consecutive examinations (n = 226). STS was defined as an average change in hearing thresholds ≥ + 10 dB at 2,000 Hz, 3,000 Hz, and 4,000 Hz in either ear. Determinants of STS were assessed through a questionnaire. The incidence of STS was 23.0%. Significant determinants of STS were the number of episodes of temporary threshold shifts (TTS) in the Navy, exposure to continuous loud noise during work on board, and the number of gun shots (in the Navy, hunting, and sports). This study indicated a significant association between noise exposure on board Navy vessels and development of STS.

  4. Hearing loss in the Royal Norwegian Navy: A longitudinal study

    Directory of Open Access Journals (Sweden)

    Kaja Irgens-Hansen

    2016-01-01

    Full Text Available The aims of this longitudinal study were to investigate a significant threshold shift (STS among personnel working on board the Royal Norwegian Navy′s (RNoN vessels between 2012 and 2014 and to identify possible determinants of STS. Hearing thresholds were measured by pure tone audiometry in two consecutive examinations (n = 226. STS was defined as an average change in hearing thresholds ≥ + 10 dB at 2,000 Hz, 3,000 Hz, and 4,000 Hz in either ear. Determinants of STS were assessed through a questionnaire. The incidence of STS was 23.0%. Significant determinants of STS were the number of episodes of temporary threshold shifts (TTS in the Navy, exposure to continuous loud noise during work on board, and the number of gun shots (in the Navy, hunting, and sports. This study indicated a significant association between noise exposure on board Navy vessels and development of STS.

  5. Royal dynasties as human inbreeding laboratories: the Habsburgs.

    Science.gov (United States)

    Ceballos, F C; Alvarez, G

    2013-08-01

    The European royal dynasties of the Early Modern Age provide a useful framework for human inbreeding research. In this article, consanguineous marriage, inbreeding depression and the purging of deleterious alleles within a consanguineous population are investigated in the Habsburgs, a royal dynasty with a long history of consanguinity over generations. Genealogical information from a number of historical sources was used to compute kinship and inbreeding coefficients for the Habsburgs. The marriages contracted by the Habsburgs from 1450 to 1750 presented an extremely high mean kinship (0.0628±0.009), which was the result of the matrimonial policy conducted by the dynasty to establish political alliances through marriage. A strong inbreeding depression for both infant and child survival was detected in the progeny of 71 Habsburg marriages in the period 1450-1800. The inbreeding load for child survival experienced a pronounced decrease from 3.98±0.87 in the period 1450-1600 to 0.93±0.62 in the period 1600-1800, but temporal changes in the inbreeding depression for infant survival were not detected. Such a reduction of inbreeding depression for child survival in a relatively small number of generations could be caused by elimination of deleterious alleles of a large effect according with predictions from purging models. The differential purging of the infant and child inbreeding loads suggest that the genetic basis of inbreeding depression was probably very different for infant and child survival in the Habsburg lineage. Our findings provide empirical support that human inbreeding depression for some fitness components might be purged by selection within consanguineous populations.

  6. Fibrous osteodystrophy in two Northern Royal albatross chicks (Diomedea sanfordi).

    Science.gov (United States)

    Morgan, K J; Alley, M R; Gartrell, B D; Thompson, K G; Perriman, L

    2011-09-01

    In February 2004, two Northern Royal albatross chicks aged 20 and 25 days old were presented for necropsy. Both chicks had been hand-fed in situ at a breeding colony, from 2-3 days post-hatch. The hand-rearing diet consisted of boneless hoki fillets (Macraronus novaezelandiae), electrolytes, and sooty shearwater (Puffinus griseus) proventricular oil obtained as a by-product of cultural harvest. Routine necropsies on the affected chicks revealed many bones were soft and easily bent. Radiography and histopathology revealed decreased bone density, pathological fractures, and extensive remodelling suggestive of fibrous osteodystrophy. Nutritional secondary hyperparathyroidism, resulting from an imbalance in the dietary Ca:P ratio. The imbalance in the dietary Ca:P ratio was a result of feeding deboned and eviscerated fish. This investigation also highlighted potential health risks associated with the practice of feeding stored rancid proventricular oil, including the destruction of fat-soluble vitamins. It is therefore possible that oxidative degradation of vitamin D may have contributed to the development of nutritional secondary hyperparathyroidism. Subsequently, dietary recommendations for supplementary feeding of orphaned Northern Royal albatross chicks include the feeding of whole human-grade fish with an appropriate Ca:P ratio, and the exclusion of proventricular oil. These cases highlight the need for scientific input into wildlife conservation projects, as lack of appropriate nutritional advice resulted in the feeding of a nutritionally inadequate diet. Following the recommended changes in diet, no further cases of osteodystrophy have been diagnosed in hand-raised chicks in the albatross colony.

  7. Yaitya tirka madlanna warratinna: exploring what sexual health nurses need to know and do in order to meet the sexual health needs of young Aboriginal women in Adelaide.

    Science.gov (United States)

    Kelly, Janet; Luxford, Yoni

    2007-07-01

    Young Aboriginal women are consistently identified as having poorer health outcomes and access to sexual health services than non-Indigenous Australians. Yet the literature is particularly silent on what sexual health nurses need to know and do in order to work well with young urban Aboriginal women. This paper reports on a qualitative pilot study undertaken by a non-Indigenous nurse in Adelaide. The participatory action research methods used in this study were sensitive to the history of problems associated with research in Aboriginal communities. A reference group of Elder Aboriginal women and Aboriginal health workers guided all aspects of the study. A partnership approach between the researcher and the Reference Group ensured that the methods, analysis, and final report were culturally safe. Three groups participated in this study: Elders and Aboriginal health workers; young Aboriginal women, and sexual health nurses. All participants acknowledged the importance of nurses being clinically competent. However, the overarching finding was a lack of a clear model of cultural care to guide health service delivery. Three interrelated themes emerged from the data to support this contention. These were: the structural and personal importance of establishing and maintaining trustworthy relationships between nurses, Aboriginal health workers and Elders; the recognition that Aboriginal culture does exist, and is important in urban areas; and the importance of gender considerations to understanding urban women's health business. A partnership approach was recommended as a way to use these findings to develop a transparent cultural model of care. Further research is currently being undertaken to progress this agenda.

  8. Accuracy of target localisation and alignment in stereotactic radiosurgery at Royal Prince Alfred Hospital

    International Nuclear Information System (INIS)

    Downes, S.

    1996-01-01

    Full text: Over the last 30 years, stereotactic radiosurgery has become an effective clinical tool in the treatment of intra-cranial lesions. The use of high doses to a specific target volume in a single fraction and the proximity of critical organs requires very accurate geometric localisation of the various cranial structures (using CT, MRI and angiography imaging) and accurate alignment of the target volume prior to treatment. The purpose of this paper was to determine the accuracy of localising cranial structures using computed tomography and angiographic imaging modalities and to determine the accuracy of aligning the treatment isocentre to the specified coordinates. The sum of these two errors will give the total deviation of the treated target from the actual target. Measurements were made using an anthropomorphic (ART) phantom of an adult male and a cerrobend target. The ART phantom was immobilised using the Brown-Roberts-Wells (BRW) ring. The cerrobend target was inserted into the skull at 10 different positions. Each of these 10 positions were scanned using CT and angiographic imaging and localised using the stereotactic planning software. For each test position, the ART phantom was placed on the treatment couch and aligned to the treatment coordinates determined using localisation (CT and angiography). A-P and lateral port films were then made of the target. The distance between the centre of the cerrobend target (intended target) and the centre of radiation (actual target) was the total error in localisation and alignment of the target. For computed tomography, the measurements showed the average error in localisation and alignment of the target was ±0.7mm. In terms of coordinate axis, the average error was: A-P axis = ±0.5mm, Lateral(left-right) Axis = ±0.3mm, Vertical(inferior superior) Axis ±0.4mm. From these measurements it was shown that using the stereotactic radiosurgery planning system and hardware, cranial lesions could be localised and treated with sub-millimetre accuracy. Minor improvements in accuracy might occur as experience with the system grows particularly in alignment of the target before treatment. However overall accuracy is limited by the method of imaging used in localisation of the target

  9. Art in wartime: The First Wounded, London Hospital, August 1914.

    Science.gov (United States)

    Park, M P; Park, R H R

    2011-06-01

    John Lavery's The First Wounded, London Hospital, August 1914 records a memorable event in the First World War. This painting and the archives of the Royal London Hospital provide a fascinating insight into the nursing and medical care of these early war casualties.

  10. The Relationship Between Soils and Foliar Nutrition For Planted Royal Paulownia

    Science.gov (United States)

    James E. Johnson; David O. Mitchem; Richard E. Kreh

    2002-01-01

    Royal paulownia is becoming an important hardwood plantation species in the southern U.S. A study was done to investigate two novel site preparation techniques for aiding the establishment of royal paulownia seedlings in the Virginia Piedmont. The effects of these treatments on the foliar nutrition of first year seedlings was determined, as was the relationship...

  11. Evaluation of royal jelly as an alternative to fetal bovine serum in cell ...

    African Journals Online (AJOL)

    Background: Royal jelly is a nutritious substance produced by the young nurse bees and contains significant amounts of proteins which are important for cell growth ... In the Alamar Blue assay, 0.156 and 0.078 mg/ml of royal jelly produced greater percentage of reduction at day 3 even though no significant difference was ...

  12. 78 FR 77772 - Culturally Significant Objects Imported for Exhibition Determinations: “A Royal Passion: Queen...

    Science.gov (United States)

    2013-12-24

    ... DEPARTMENT OF STATE [Public Notice 8570] Culturally Significant Objects Imported for Exhibition Determinations: ``A Royal Passion: Queen Victoria and Photography'' SUMMARY: Notice is hereby given of the... that the objects to be included in the exhibition ``A Royal Passion: Queen Victoria and Photography...

  13. 78 FR 42512 - Application to Export Electric Energy; Royal Bank of Canada

    Science.gov (United States)

    2013-07-16

    ... DEPARTMENT OF ENERGY [OE Docket No. EA-342-A] Application to Export Electric Energy; Royal Bank of.... SUMMARY: Royal Bank of Canada (RBC) has applied to renew its authority to transmit electric energy from..., 2008, DOE issued Order No. EA-342, which authorized RBC to transmit electric energy from the United...

  14. 77 FR 62311 - Culturally Significant Objects Imported for Exhibition Determinations: “Royal Treasures From the...

    Science.gov (United States)

    2012-10-12

    ... DEPARTMENT OF STATE [Public Notice 8061] Culturally Significant Objects Imported for Exhibition Determinations: ``Royal Treasures From the Louvre: Louis XIV to Marie- Antoinette'' SUMMARY: Notice is hereby... objects to be included in the exhibition ``Royal Treasures from the Louvre: Louis XIV to Marie-Antoinette...

  15. 76 FR 33019 - Waiver of Restriction on Assistance to the Royal Government of Cambodia

    Science.gov (United States)

    2011-06-07

    ... DEPARTMENT OF STATE [Public Notice: 7491] Waiver of Restriction on Assistance to the Royal Government of Cambodia Pursuant to Section 7086(c)(2) of the Department of State, Foreign Operations, and... waive the requirements of Section 7086(c)(1) of the Act with respect to the Royal Government of Cambodia...

  16. Improved ovulation rate and implantation in rats treated with royal jelly

    African Journals Online (AJOL)

    The ovaries and uteris of 12 mature female rats (Rattus norvegicus) were examined to determine the effect of commercial royal jelly on ovulation, ovarian weight and implantation rates. Rats were split in two groups of 6 each. Group one served as the treatment and group two the control. A daily dose of 25mg of royal jelly ...

  17. A STUDY ABOUT PHYSICOCHEMICAL COMPOSITION OF FRESH AND LYOPHILIZED ROYAL JELLY

    Directory of Open Access Journals (Sweden)

    OLIMPIA POPESCU

    2008-10-01

    Full Text Available This paper contents a summery about physicochemical composition of frash and lyophilized royal jelly. Royal jelly (RJ is a yellowish and creamy secretion from hypo pharyngeal and mandibular glands of young worker bees (Apis mellifera L. to feed all larvae for the first three days of their life and the queen bee for both her larval life and adulthood.. Royal jelly is a honey bee secretion that is used in the nutrition of the larvae. Queen bees are made, not born, and their feeding with royal jelly is the key to that process. The geographical authenticity of royal jelly can be determined also by pollen analysis (Ricciardelli d'Albore et al., 1978; Ricciardelli d'Albore, 1986. The physicochemical composition of pure royal jelly are analyzed by determining moisture, ash, lipids, proteins, carbohydrates, 10-HDA; and for lyophilized royal jelly are analyzed by determining ash, lipids, protein, carbohydrates, 10-HDA, sugars. 10-HDA content is the criteria of royal jelly quality analysis and it is a freshness parameter(Antinelli J.F., Sarah Zeggane, Renee Davico, Catherine Rognone, Jean Paul Faucon, Louisette Lizzani.

  18. Quality of royal jelly produced by Africanized honeybees fed a supplemented diet

    Directory of Open Access Journals (Sweden)

    Maria Josiane Sereia

    2013-06-01

    Full Text Available This study was carried out to evaluate the effect of artificial supplements prepared with soybean protein isolate, brewer's yeast, mixture of soybean protein isolate with brewer's yeast, linseed oil, palm oil, and a mixture of linseed oil with palm oil on the physicochemical and microbiological composition of royal jelly produced by Africanized honey bee colonies. Considering these results, providing supplements for Africanized honeybee colonies subjected to royal jelly production can help and strengthen the technological development of the Brazilian beekeeping industry increasing its consumption in the national market. This research presents values of royal jelly a little different from those established by the Brazilian legislation. This fact shows that is important to discuss or change the official method for royal jelly analysis. The characterization of physicochemical and microbiological parameters is important in order to standardize fresh, frozen, and lyophilized royal jelly produced by Africanized honeybees.

  19. BOOK REVIEW: Robert Hooke and the Royal Society

    Science.gov (United States)

    Brown, Neil

    2000-01-01

    Many physics students only come across Hooke when they learn his law of stretching springs, which is a pity because it is just one of his contributions to progress in science, and a minor one at that. His, Micrographia, the first great book of microscopical observations, arouses admiration to this day. He was also active in horology, astronomy, geology and surveying, and he took part in biological experiments, transfusing blood between animals. Much of his work was done while he was curator of experiments for the Royal Society, in which he was involved almost from its foundation. This was by no means a full-time occupation, however. After the Great Fire of London, Hooke was appointed one of the three surveyors for the rebuilding of the city. One of the others was Christopher Wren, a lifelong friend. In this role Hooke was responsible for the design of several buildings, including the Monument. Nichols writes about all these activities, as well as Hooke's childhood, his education at Westminster School, the University of Oxford when Hooke was an undergraduate, and the founding of the Royal Society. The book draws on research for a master's degree. Turning a dissertation into a popular book is risky. The author has avoided the pitfall of making it too academic, but the result is not satisfying. Nichols seems overawed by Hooke and his work, frequently seeming to credit Hooke with a far-reaching influence that he did not necessarily have. There may be a case for lauding Hooke as the father of English microscopy, the father of English meteorology, and the founder of English geology and earth sciences, but it needs to be made much more critically, even in a popular work. Hooke was full of good ideas, but he rarely continued long enough to put them into practice. There is no doubt that Hooke proposed using a balance wheel and spring to improve the timekeeping of a watch, for example, but he did not have a watch made to his design until after Christiaan Huygens had

  20. Conventual Writing and Context: The Case of Port-Royal

    Directory of Open Access Journals (Sweden)

    John J. Conley

    2018-03-01

    Full Text Available Many of the spiritual texts produced in the early modern period were written by nuns. To teach these texts adequately, it is not sufficient to study the work itself or the biography of the author. Effective exegesis of the texts requires detailed attention to the conventual culture in which these works were written, since this culture is foreign to the vast majority of contemporary students and readers. This contextual analysis operates on three levels. The first level introduces the students to the general nature of the convent and the life of a nun: the evangelical vows, the rule/constitution of the order, and the different types of religious orders. The second level focuses on the specific culture of the convent where the texts were composed. This involves analysis of the convent’s particular spirituality, apostolate, literary genres of communication, and relationship to broader ecclesiastical and political movements of the times. The third level studies the gendered nature of the nuns’ writings. This contextualist-cultural method of teaching écriture couventuelle is illustrated through analysis of the writings of the prolific Port-Royal abbess, Angélique de Saint-Jean Arnauld d’Andilly.

  1. Domingos Vandelli and the deficit in royal Portuguese treasury

    Directory of Open Access Journals (Sweden)

    Ricardo Dalla Costa

    2015-12-01

    Full Text Available This work aims to discuss the economic situation and policy recommendations of Vandelli to solve the difficulties in economic situation in Portugal at the end of seven hundred. Starting with a prior proposal for Vandelli on institutionalization of knowledge in Sciencia of Finance to further expose the difficulties in maintaining the Kingdom in not justifiable times as costly ordered and even military expenditures, investments in manufacturing, arts and science without there being at that time a real war economy. As a result, it failed to materialize the idea of a Portuguese Economic Society since it was transmuted into a Science Academy. With regard to the deficit in the Royal Treasury, there was an increase of Portuguese State spending concurrently with the drop in revenue from overseas, and finally opportunism behind the financial difficulties of the metropolis led Vandelli to do harsh criticism to financial managers and usurers who took advantage of an emblematic situation and suggest economic policies to balance public finances

  2. Rama in the royal title of the Hungarian kings

    Directory of Open Access Journals (Sweden)

    Živković Tibor D.

    2004-01-01

    Full Text Available The region (župa of Rama was enlisted in the official title of the Hungarian kings around 1138, as it is known from an official document. The exact answer to the question under which circumstances it happened has never been reached. It is most probable that Rama was not just other name for Bosnia as it was proposed in historiography, neither was a part of Bosnia conquered by military action of the Hungarian king around 1135. Having in mind that Rama was a part of the principality of Raška during the Early Middle Ages, it is quite possible that Rama became part of the official title of the Hungarian kings through some direct connections between ruling families of Hungary and Raška. The most probable answer could be reached through the examination of these relations. Namely, a daughter of Raška's župan, Uroš I, Helena, was married to the Hungarian crown prince Bela in 1129, when Rama was, most probably, part of Helena's dowry. When the crown prince became king of Hungary in 1131, Rama was included in his royal title. Later on during the Middle Ages Rama became part of Bosnia giving ground to the Hungarian kings to claim whole Bosnia as their heritage. .

  3. The BINA collaboration: science at the Royal Observatory of Belgium

    Science.gov (United States)

    De Cat, Peter; Cuypers, Jan; Blomme, Ronny; Frémat, Yves; Groenewegen, Martin; Lampens, Patricia; Lobel, Alex; Pauwels, Thierry; Van de Steene, Griet; van Hoof, Peter

    2018-04-01

    The Belgo-Indian Network for Astronomy and Astrophysics (BINA) is a collaboration between Indian and Belgian astronomical institutes with the main aim to optimize the scientific output of the Indo-Belgian telescopes, being the 4.0-m International Liquid Mirror Telescope and the 3.6-m Devasthal Optical Telescope. These new facilities are both located at the Devasthal Observatory near Nainital, India. In this contribution, we introduce projects that are of scientific interest for colleagues of the department "Astronomy and Astrophysics" of the Royal Observatory of Belgium (ROB). It serves as an invitation for Indian astronomers to participate. We highlight how these projects could benefit from observations with the Indo-Belgian telescopes by using instruments from the first-generation (currently offered) and/or the next-generation (development or design phase). We show that, from an ROB point-of-view, the BINA would be the most successful if the 3.6-m DOT would be equipped with an efficient optical high-resolution spectrograph.

  4. The significance and lag-time of deep through flow: an example from a small, ephemeral catchment with contrasting soil types in the Adelaide Hills, South Australia

    Directory of Open Access Journals (Sweden)

    J. VanLeeuwen

    2009-07-01

    Full Text Available The importance of deep soil-regolith through flow in a small (3.4 km2 ephemeral catchment in the Adelaide Hills of South Australia was investigated by detailed hydrochemical analysis of soil water and stream flow during autumn and early winter rains. In this Mediterranean climate with strong summer moisture deficits, several significant rainfalls are required to generate soil through flow and stream flow [in ephemeral streams]. During autumn 2007, a large (127 mm drought-breaking rain occurred in April followed by significant May rains; most of this April and May precipitation occurred prior to the initiation of stream flow in late May. These early events, especially the 127 mm April event, had low stable water isotope values compared with later rains during June and July and average winter precipitation. Thus, this large early autumn rain event with low isotopic values (δ18O, δD provided an excellent natural tracer. During later June and July rainfall events, daily stream and soil water samples were collected and analysed. Results from major and trace elements, water isotopes (δ18O, δD, and dissolved organic carbon analysis clearly demonstrate that a large component of this early April and May rain was stored and later pushed out of deep soil and regolith zones. This pre-event water was identified in the stream as well as identified in deep soil horizons due to its different isotopic signature which contrasted sharply with the June–July event water. Based on this data, the soil-regolith hydrologic system for this catchment has been re-thought. The catchment area consists of about 60% sandy and 40% clayey soils. Regolith flow in the sandy soil system and not the clayey soil system is now thought to dominate the deep subsurface flow in this catchment. The clayey texture contrast soils had rapid response to rain events and saturation excess overland flow. The sandy soils had delayed soil through flow and

  5. The quality of operative note taking: an audit using the Royal College of Surgeons Guidelines as the gold standard.

    Science.gov (United States)

    Shayah, A; Agada, F O; Gunasekaran, S; Jassar, P; England, R J A

    2007-04-01

    To assess the quality of operative note keeping and compare the results with the Royal College of Surgeons (RCS) of England guidelines 'Good Surgical Practice' as the gold standard. ENT Department at Hull Royal Infirmary, University Hospital. A hundred consecutive operative notes were selected between November 2005 and January 2006. The documentation of the operative notes in each case was compared with the RCS of England guidelines. All surgeons were made aware of the results of the first cycle and the guidelines were made available in all ENT theatres in the form of a printed aide-memoir. A second audit cycle was then carried out prospectively between April and June 2006. The results demonstrated a change in practice in key areas. The 1st cycle results showed the documentation of patient identification (94%), name of surgeon (98%) and clearly written postoperative instructions (94%). However, surgeons performed suboptimally at recording the name of assistant (82%), operative diagnosis (46%), the incision type (87%) and the type of wound closure (83%). After introducing the aide-memoir, the second cycle demonstrated a change in practice with 100% documentation in most of the assessed parameters except that the time of surgery and the type of surgery (emergency or elective) were not adequately recorded. We recommend that all surgical departments should have the RCS guidelines as an aide-memoir in theatres to enhance the quality and standardise operative note recording.

  6. Hospital management. The reflective practitioner.

    Science.gov (United States)

    Campbell, I

    Ian Campbell's paper, originally delivered at a conference on the development of 'The reflective practitioner' while he was Unit General Manager of Sunderland Royal Infirmary, describes the liaison between general and nurse managers in the hospital. Management must give a hospital organisation direction and must set the parameters of corporate and individual performance, but it must also be responsive to the feedback received from practising clinicians. The key concept is quality of service, and in this managers and practitioners can work together towards a common goal.

  7. Concours annuels Academie Royale des Sciences d'Outre-mer

    Directory of Open Access Journals (Sweden)

    Royal Academy for Overseas Sciences

    2011-01-01

    Full Text Available Yearly competitions Royal Academy for Overseas Sciences. L'Organisation des Nations Unies, face aux inégalités croissantes a initié le processus des Objectifs du Millénaire pour le Développement (OMD qui doivent être réalisés d'ici 2015. L'atteinte des huit OMD devrait permettre de réduire la pauvreté et d'améliorer les conditions de vie des populations. L'élevage est pratiqué par une grande partie de la population mondiale surtout les plus pauvres. Il est pourvoyeur d'emplois et contribue à l'émancipation des femmes grâce aux revenus générés par la vente des produits animaux. Les animaux d'élevage sont également utilisés pour le transport et la culture attelée. La forte densité en nutriments des produits animaux en fait des aliments de choix pour améliorer l'état nutritionnel des enfants. La domestication des espèces animales sauvages et le développement de l'aquaculture contribuent à réduire les prélèvements dans la nature et à protéger la biodiversité. Le développement d'un élevage durable et raisonné peut donc positivement impacter plusieurs secteurs et doper la croissance économique des pays. Ce qui peut aider les pays en développement à se rapprocher des OMD d'ici 2015. La note présente également les pré-requis pour rendre effective la contribution de l'élevage aux.

  8. The Sigiriya Royal Gardens. Analysis of the Landscape Architectonic Composition

    Directory of Open Access Journals (Sweden)

    Jude Nilan Cooray

    2017-11-01

    Full Text Available Besides the efforts that are of descriptive and celebrative nature, studies related to Sri Lanka’s historical built heritage are largely to view material remains in historical, sociological, socio-historical and semiological perspectives. But there is hardly any serious attempt to view such material remains from a technical-analytical approach to understand the compositional aspects of their designs. The 5th century AC royal complex at Sigiriya is no exception in this regard. The enormous wealth of information and the unearthed material remains during more than hundred years of field-based research by several generations of archaeologists at Sigiriya provide ideal opportunity for such an analysis. The present study is, therefore, to fill the gap in research related to Sri Lanka’s historical built heritage in general and to Sigiriya in particular. Therefore the present research attempts to read Sigiriya as a landscape architectonic design to expose its architectonic composition and design instruments. The study which is approached from a technical-analytical point of view follows a methodological framework that is developed at the Landscape Design Department of the Faculty of Architecture at Delft University of Technology. The study reveals that the architectonic design of Sigiriya constitutes multiple design layers and multiple layers of significance with material-spatial-metaphorical-functional coherence, and that it has both general and unique landscape architectonic elements, aspects, characteristics and qualities. The richness of its composition also enables to identify the landscape architectural value of the Sigiriya, which will help re-shape the policies related to conservation and presentation of Sigiriya as a heritage site as well as the protection and management as a green monument. The positive results of the study also underline that the methodology adapted in this research has devised a framework for the study of other examples

  9. Royal Jelly Inhibits Pseudomonas aeruginosa Adherence and Reduces Excessive Inflammatory Responses in Human Epithelial Cells

    Directory of Open Access Journals (Sweden)

    Heni Susilowati

    2017-01-01

    Full Text Available Pseudomonas aeruginosa is a Gram-negative bacterium and causes respiratory infection especially in elderly patients. Royal jelly has been used worldwide as a traditional remedy and as a nutrient; however, the effect against P. aeruginosa is unclear. The aim of this study was to analyze antibacterial, antiadherent, and anti-inflammatory effects of royal jelly against P. aeruginosa. Wild-type strain PAO1 and clinical isolates of P. aeruginosa were used for antibacterial assay and antiadherent assay to abiotic surface and epithelial cells, which are pharynx (Detroit 562 and lung (NCI-H292 epithelial cells. In anti-inflammatory assay, epithelial cells were pretreated with royal jelly before bacterial exposure to investigate its inhibitory effect on interleukin (IL-8 and macrophage inflammatory protein-3α/CCL20 overproduction. Although royal jelly did not have antibacterial activity at concentration of 50% w/v, antiadherent activity was confirmed on the abiotic surface and epithelial cells under concentration of 25%. Pretreatment with royal jelly significantly inhibited overproduction of IL-8 and CCL20 from both cells. These results demonstrated that royal jelly inhibits P. aeruginosa adherence and protects epithelial cells from excessive inflammatory responses against P. aeruginosa infection. Our findings suggested that royal jelly may be a useful supplement as complementary and alternative medicine for preventing respiratory infection caused by P. aeruginosa.

  10. Body-enlarging effect of royal jelly in a non-holometabolous insect species, Gryllus bimaculatus

    Directory of Open Access Journals (Sweden)

    Atsushi Miyashita

    2016-06-01

    Full Text Available Honeybee royal jelly is reported to have body-enlarging effects in holometabolous insects such as the honeybee, fly and silkmoth, but its effect in non-holometabolous insect species has not yet been examined. The present study confirmed the body-enlarging effect in silkmoths fed an artificial diet instead of mulberry leaves used in the previous literature. Administration of honeybee royal jelly to silkmoth from early larval stage increased the size of female pupae and adult moths, but not larvae (at the late larval stage or male pupae. We further examined the body-enlarging effect of royal jelly in a non-holometabolous species, the two-spotted cricket Gryllus bimaculatus, which belongs to the evolutionarily primitive group Polyneoptera. Administration of royal jelly to G. bimaculatus from its early nymph stage enlarged both males and females at the mid-nymph and adult stages. In the cricket, the body parts were uniformly enlarged in both males and females; whereas the enlarged female silkmoths had swollen abdomens. Administration of royal jelly increased the number, but not the size, of eggs loaded in the abdomen of silkmoth females. In addition, fat body cells were enlarged by royal jelly in the silkmoth, but not in the cricket. These findings suggest that the body-enlarging effect of royal jelly is common in non-holometabolous species, G. bimaculatus, but it acts in a different manner than in holometabolous species.

  11. The Madrid Royal Schools of St. Elisabeth and Loreto according Constitutions of 1715 and 1718

    Directory of Open Access Journals (Sweden)

    Beatriz COMELLA GUTIÉRREZ

    2013-02-01

    Full Text Available The Madrid Royal Schools of Saint Elizabeth and Loreto were founded by Philip II at the end of 16th Century. Both institutions provided education for orphan girls. They still exist as Catholic coeducational schools granted by the Education Department. These two Schools were Royal Sponsorship belonging to Palace ecclesiastical jurisdiction. The Schools Constitutions sanctioned by Philip V have been preserved until now. Although these Schools have a parallel history, the mentioned Constitutions are completely different for each School. According to these Norms, the Madrid Royal Schools of Saint Elizabeth and Loreto have many differences between them.

  12. Pouvoir et religion à la chapelle royale de Versailles sous Louis XIV Power and religion at the royal chapel of Versailles under Louis XIV

    Directory of Open Access Journals (Sweden)

    Alexandre Maral

    2007-12-01

    Full Text Available D’une manière peut‑être plus sensible que partout ailleurs, les objets et les insignes du pouvoir prennent une importance particulière dans le contexte du cérémonial liturgique de la religion catholique. À la chapelle royale de Versailles, la présence régulière du monarque et de sa cour complique encore la situation, d’autant que la desserte est assurée par deux corps distincts d’ecclésiastiques. Dépassant le simple cadre des préséances, Louis XIV a défini autour de sa personne royale un système rituel susceptible d’en manifester le caractère épiscopal dérivé du sacre. De même, l’enjeu juridictionnel représenté par la Chapelle royale se traduit par un jeu subtil d’attitudes, de gestes et de rites, chorégraphie sacrée qui accompagne et exprime les revendications des partisans et des adversaires de l’exemption du lieu de culte royal au regard du diocèse de Paris. Ce discours trouve un écho partiel dans le programme décoratif de la chapelle définitive du palais, achevée en 1710.Objects and symbols of power take on a particular importance in the liturgical ceremony of the Catholic Church, perhaps more so than in any other context. At the royal chapel of Versailles, the regular presence of the king and his court complicated the situation further, all the more so in that religious ceremony was administered by two distinct ecclesiastic bodies. Beyond the rules of precedence, Louis XIV had introduced around his royal persona a system of ritual that would manifest the episcopal identity conferred upon him by his coronation. Similarly, the jurisdictional authority represented by the royal chapel was conveyed in a subtle play of attitudes, gestures and rites, a symbolic choreography that accompanied and expressed the claims of the partisans and adversaries of the exemption of the royal place of worship with regard to the diocese of Paris. This stance was reflected in the decorative scheme of the palace

  13. Royal-Dutch Shell in Russia and Western Sanctions

    Directory of Open Access Journals (Sweden)

    Konstantin Kurilev

    2017-03-01

    Full Text Available This article reports on research based on three crucial aspects of the current global economic situation. First is the role of transnational corporations (TNCs in establishing and constructing international cooperation at the supranational level. Second is the policy of sanctions against Russia in connection with the situation in Ukraine. And third is the cooperation of Royal Dutch Shell with Russia’s Gazprom despite the political, economic and technological sanctions imposed on Russian companies and economic sectors.Analyzing Shell’s policy on the Russian energy market should reveal some kind of the managing principle that not only Shell but most TNCs follow in taking the political atmosphere into consideration, while striving to avoid any related restrictions. The research methodology uses analytical, ultimate analysis and functional methods. The analytical method helped to lay the theoretical foundation of the research. Modern TNCs are deeply engaged in the process of economic globalization. To expand their influence, such companies create economic conditions for organizing international production with local markets and for international markets for capital, labour, and scientific and consulting services. The ultimate analysis method revealed the following pattern: in struggling for the global market, TNCs raise the level of competition, which creates a permanent need for technical innovations and scientific progress. The functional analysis method demonstrated a casual relationship in modern economic development: by assisting capital turnover and labour and transport mobility, TNCs contribute significantly to economic growth and development. The first part of the article focuses on the history and methodology of the genesis and development of TNCs as actors in global economic relations. It also reviews the current role of TNCs in the global economy. The second part of the article examines the cooperation between Shell and Gazprom

  14. Royal Service on Eesti mainekaim üritusturundusfirma / Eda-Liis Kann

    Index Scriptorium Estoniae

    Kann, Eda-Liis, 1979-

    2005-01-01

    Turu-uuringute AS-i korraldatud üritusturunduse ettevõtete maineuuringust selgus, et kõige mainekamad Eestis on Royal Service, Event Masters, Broadline ja Sinine Elevant. Kõige madalama mainega on Tequila

  15. 'Any style but gothic': Building a home for the Royal College of Physicians of Ireland.

    Science.gov (United States)

    Wheelock, H

    2016-06-01

    On 15 July 1864 the Royal College of Physicians of Ireland held its first business meeting in its newly built home at 6 Kildare Street, Dublin. Although the Royal College of Physicians of Ireland had been in existence for over 200 years this was the first occasion that a College meeting had been held in a building owned by the College. This paper looks at the history behind the construction of a home for the Royal College of Physicians of Ireland. It will examine why it took over 200 years for the Physicians to find a permanent home, how they ended up with the building they did, and what they borrowed from the Royal College of Physicians in Edinburgh in the process.

  16. Presence of women in Royal Economic Society of Friends of the Country (1775-1808

    Directory of Open Access Journals (Sweden)

    María Consolación Calderón España

    2010-11-01

    Full Text Available In this work we present the performance of women in the work of the Royal Economic Society of Friends of the Country, institutions of the eighteenth century who sought to lift the economy of Spain in that century. Women’s participation in the Royal Economic So- ciety was carried out by the Boards of Damas and supervisory work of the Schools «patriotism» and the first letters. The first schools to be named, according to Campomanes conceived of yarn and fabric and should be established in major cities throughout the kingdom. Participation in the Royal Economic Society from all social classes and genders with equal rights, was a fact. There is no comprehensive study on all of the Royal Economic Society of Friends of the Country, therefore there is no one on women in one way or another took part in them. With this work we present the work done by some.

  17. Development of an Information Security Awareness Training Program for the Royal Saudi Naval Forces (RSNF)

    National Research Council Canada - National Science Library

    Alageel, Sami

    2003-01-01

    The Royal Saudi Naval Forces (RSNF) are vulnerable to the same kinds of threats to its information infrastructure as the rest of the industrialized nations, As an officer in the RSNF, I am familiar with the special information...

  18. Doctor William Gunn (1804-1890): From the South Pacific Islands to Chatham Royal Dockyard.

    Science.gov (United States)

    Biddle, Richard

    2016-11-24

    Doctor William Gunn had a long and varied career in the Royal Navy. After spending time on anti-slavery patrols along the west coast of Africa, he was posted to the south Pacific. At Pitcairn Island, he treated the inhabitants during an influenza epidemic, proving himself to be a determined and dedicated practitioner. Subsequently, he was appointed head of the medical department at Chatham Royal Dockyard (1859-1865), an appointment that coincided with the final stages of the Royal Navy's transition from sail and wood to steam and iron. The impact of these changes on the health of dockworkers was quickly felt at Chatham, and Gunn found himself in charge during the building of the first iron warship in a royal dockyard. His story thus offers a window through which to observe a practitioner confronting the health issues and medical uncertainties thrown up by technological change in the Victorian era. © The Author(s) 2016.

  19. Nephroprotective effect of bee honey and royal jelly against subchronic cisplatin toxicity in rats

    OpenAIRE

    Ibrahim, Abdelazim; Eldaim, Mabrouk A. Abd; Abdel-Daim, Mohamed M.

    2015-01-01

    Cisplatin is one of the most potent and effective chemotherapeutic agents. However, its antineoplastic use is limited due to its cumulative nephrotoxic side effects. Therefore, the present study was undertaken to examine the nephroprotective potential of dietary bee honey and royal jelly against subchronic cisplatin toxicity in rats. Male Wistar rats were randomly divided into controls, cisplatin-treated, bee honey-pretreated cisplatin-treated and royal jelly-pretreated cisplatin-treated grou...

  20. Marketingová strategie jazykové školy Royal School

    OpenAIRE

    Pazderská, Lucie

    2010-01-01

    The aim of this thesis is to analyse the marketing strategy of the language school Royal School and to suggest its improvement on the basis of observed data. The thesis is divided into two main parts -- theoretical and practical part. The theoretical part focuses on marketing of services and its differences especially in terms of marketing mix. In the practical part, Royal School is first briefly introduced, then there are the main features of Callan method and an evaluation of current market...

  1. The Code of Ethics and Editorial Code of Practice of the Royal Astronomical Society

    Science.gov (United States)

    Murdin, Paul

    2013-01-01

    Whilst the Royal Astronomical Society has got by for more than 100 years without a written code of ethics, modern standards of governance suggested that such a code could be useful in the resolution of disputes. In 2005, the RAS adopted the Universal Code of Ethics for Science that had been formulated by the Royal Society of London. At the same time and for similar reasons the RAS adopted an Editorial Code of Practice.

  2. The Queens' estates: fiscal properties and royal policy ( 9th -10th centuries

    Directory of Open Access Journals (Sweden)

    Tiziana Lazzari (a cura di

    2012-10-01

    Full Text Available The special condition of the queens of italic Kingdom during the 9th and 10th centuries is exemplified by the title of consors regni and by the exceptionally copious dowers bestowed to them when compared to those entrusted to other European queens. Through the accurate reconstruction of these dowries, composed of royal fiscal assets, this anomaly is explained within the context of specific royal governmental strategies.

  3. The functional property of royal jelly 10-hydroxy-2-decenoic acid as a melanogenesis inhibitor

    OpenAIRE

    Peng, Chi-Chung; Sun, Hui-Tzu; Lin, I-Ping; Kuo, Ping-Chung; Li, Jen-Chieh

    2017-01-01

    Background It has been reported that royal jelly would reduce melanin synthesis and inhibit the expression of melanogensis related proteins and genes. In this study, we evaluate the anti-melanogenic and depigmenting activity of 10-hydroxy-2-decenoic acid (10-HDA) from royal jelly of Apis mellifera. Methods In this study, we assesses the 10-HDA whitening activity in comparison with the changes in the intracellular tyrosinase activity, melanin content and melanin production related protein levl...

  4. Effect of Honey and Royal Jelly against Cisplatin-Induced Nephrotoxicity in Patients with Cancer.

    Science.gov (United States)

    Osama, Hasnaa; Abdullah, Aya; Gamal, Bassma; Emad, Dina; Sayed, Doha; Hussein, Eman; Mahfouz, Eman; Tharwat, Joy; Sayed, Sally; Medhat, Shrouk; Bahaa, Treza; Abdelrahim, Mohamed E A

    2017-07-01

    Cisplatin constitutes one of the most potent antineoplastic drugs; however, nephrotoxicity limited its eligibility for optimal clinical use. This study was designed to evaluate the role of honey and royal jelly with antioxidant properties in the protection of cisplatin-induced acute kidney injury in patients with cancer. Patients with cancer assigned for cisplatin chemotherapy were randomly divided into bee honey and royal jelly groups pretreated before the initiation and during cisplatin chemotherapeutic regimen and control group on cisplatin only. Serum creatinine and urea levels were measured before and after the chemotherapeutic cycle and over 2 cycles. Patients on crude bee honey and royal jelly capsules showed lower serum levels of renal injury products (creatinine and urea) compared to those in the control group. The changes in kidney parameters were significantly (p honey group before and after cisplatin treatment. Royal jelly was found to be effective; however, the difference in creatinine and urea levels before and after chemotherapy was not statistically significant. The use of bee honey and royal jelly as natural compounds is effective in reducing cisplatin nephrotoxicity and may offer a promising chance for clinically meaningful prevention. This study has potentially important implications for the treatment of cisplatin kidney side effects and is considered to be the first to investigate this effect of honey and royal jelly in human subjects. However, due to its small sample size, we recommend further investigation using a larger sample size.

  5. The Acoustics of the Double Elliptical Vault of the Royal Palace of Caserta (Italy

    Directory of Open Access Journals (Sweden)

    Umberto Berardi

    2017-03-01

    Full Text Available This work investigates the acoustic characteristics of the double elliptical vault, which overlooks the Grand Staircase of the Royal Palace of Caserta (Italy. The Royal Palace was built by the architect Luigi Vanvitelli in the Seventeenth Century and it is the largest royal building in Italy. The double elliptical vault presents a great scenography effect. Inside the vault, on the planking level, musicians used to play for the king and his guests when the royal procession, going up the grand staircase, entered the royal apartments, creating astonishment among the guests who heard the music without understanding from where it was coming. Since the musicians were inside the vault, the long reverberation made the listeners perceive the vault to be enveloped by the music. To investigate this effect, the acoustic characteristics of the double vault were measured, putting the sound source on the planking level of the vault, while the microphones were put along the staircase and in the vestibule towards the royal apartments. Finally, the spatial distribution of several acoustic parameters is evaluated also using architectural acoustic simulations.

  6. Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits

    Directory of Open Access Journals (Sweden)

    Visweswara Rao Pasupuleti

    2017-01-01

    Full Text Available Background. There are several health benefits that honeybee products such as honey, propolis, and royal jelly claim toward various types of diseases in addition to being food. Scope and Approach. In this paper, the effects of honey, propolis, and royal jelly on different metabolic diseases, cancers, and other diseases have been reviewed. The modes of actions of these products have also been illustrated for purposes of better understanding. Key Findings and Conclusions. An overview of honey, propolis, and royal jelly and their biological potentials was highlighted. The potential health benefits of honey, such as microbial inhibition, wound healing, and its effects on other diseases, are described. Propolis has been reported to have various health benefits related to gastrointestinal disorders, allergies, and gynecological, oral, and dermatological problems. Royal jelly is well known for its protective effects on reproductive health, neurodegenerative disorders, wound healing, and aging. Nevertheless, the exact mechanisms of action of honey, propolis, and royal jelly on the abovementioned diseases and activities have not been not fully elucidated, and further research is warranted to explain their exact contributions.

  7. The absolute configurations of hydroxy fatty acids from the royal jelly of honeybees (Apis mellifera).

    Science.gov (United States)

    Kodai, Tetsuya; Nakatani, Takafumi; Noda, Naoki

    2011-03-01

    9-Hydroxy-2E-decenoic acid (9-HDA) is a precursor of the queen-produced substance, 9-oxo-2E-decenoic acid (9-ODA), which has various important functions and roles for caste maintenance in honeybee colonies (Apis mellifera). 9-HDA in royal jelly is considered to be a metabolite of 9-ODA produced by worker bees, and it is fed back to the queen who then transforms it into 9-ODA. Recently we found that 9-HDA is present in royal jelly as a mixture of optical isomers (R:S, 2:1). The finding leads us to suspect that chiral fatty acids in royal jelly are precursors of semiochemicals. Rather than looking for semiochemicals in the mandibular glands of the queen bee, this study involves the search for precursors of pheromones from large quantities of royal jelly. Seven chiral hydroxy fatty acids, 9,10-dihydroxy-2E-decenoic, 4,10-dihydroxy-2E-decenoic, 4,9-dihydroxy-2E-decenoic, 3-hydroxydecanoic, 3,9-dihydroxydecanoic, 3,11-dihydroxydodecanoic, and 3,10-dihydroxydecanoic acids were isolated. The absolute configurations of these acids were determined using the modified Mosher's method, and it was revealed that, similar to 9-HDA, five acids are present in royal jelly as mixtures of optical isomers.

  8. Hospitals; hospitals13

    Data.gov (United States)

    University of Rhode Island Geospatial Extension Program — Hospital Facilities information was compiled from several various sources. Main source was the RI Department of Health Facilities Regulation database, License 2000....

  9. Varroa destructor mite in Africanized honeybee colonies Apis mellifera L. under royal jelly or honey production

    Directory of Open Access Journals (Sweden)

    Pedro da Rosa Santos

    2015-08-01

    Full Text Available This study evaluated the level of invasion of Varroa mite into worker brood cells, the infestation rate on adult worker honeybees, total and effective reproduction rates of the mite in Africanized honeybee colonies under royal jelly or honey production. Invasion and infestation rates were not statistically different between honeybee colonies producing honey or royal jelly and the averages for these parameters were 5.79 and 8.54%, respectively. Colonies producing honey presented a higher (p < 0.05 total and effective reproduction of Varroa than colonies producing royal jelly. There was a negative correlation between levels of invasion and infestation with minimum external temperature, relative humidity and rainfall. The variables month and season influenced the development of the mite, but rates were low and within the range normally found in Brazil for Africanized honeybee colonies, which confirm the greater resistance of these honeybees to Varroa destructor than European honeybees.

  10. Dimitrie Gusti and the Royal Cultural Foundations (1922-1948. Archive Documents

    Directory of Open Access Journals (Sweden)

    PhD Student Laura-Rodica Hîmpa

    2016-01-01

    Full Text Available This research aims to emphasize the activity of The "Prince Carol" Royal Cultural Foundation created in 1921 in order to lead to the emancipation especially of villages, but also the Romanian culture in a more general perspective. Overall, we may say that the period between the two world wars was marked, also due to the help of the Royal Cultural Foundation, by substantial progress in various fields of education, science and culture in general and thus contributed to changing Romania into a state with a high level of culture and the creation of an image and prestige that commanded worldwide respect. The research was done on the basis of the documents studied at the Service of the National Central Historical Archives, the Stock of the "Prince Carol" Royal Cultural Foundation and at the Library of the Romanian Academy.

  11. [Carl Gustav Carus, the first director of the newly established maternity institute of the Dresden Royal Surgical-Medical Academy 1814-1827].

    Science.gov (United States)

    Sarembe, B

    1989-01-01

    Carl Gustav Carus was born in 1789 in Leipzig. He studied at the University of Leipzig. His specialization in Gynecology and Obstetrics took place at the Triersches Maternity Hospital. In 1814 he was named Professor for Obstetrics in Dresden at the Royal-Surgical-Medical-Academy. He was the head of the Maternity Hospital till 1827. Under his direction many midwives, students and physicians were educated. He published numerous articles and books on medical and philosophical-psychological topics. He was a talented artist of the Romantic especially in painting landscapes. He was a friend of Caspar David Friedrich and Johann Wolfgang von Goethe. After 1827 he was the physician in ordinary to 3 saxonian kings. He died in 1869. The Medical Academy in Dresden bears his name "Carl Gustav Carus" since its foundation.

  12. ‘All Touched my Hand’: Queenly Sentiment and Royal Prerogative

    Directory of Open Access Journals (Sweden)

    Rachel Bates

    2015-05-01

    Full Text Available The Crimean War occurred during a formative period of ‘civic publicness’, a term used by John Plunkett to describe the press-mediated public duties undertaken by Victoria and Albert to affirm the monarchy’s popular constitution. The war triggered significant royal intervention into the condition of the army, one of the few sites of royal prerogative. At a time when aristocratic governance was being attacked and the privations of soldiers exposed to an unprecedented extent, the monarchy was keen both to legitimize its role as head of the army and to demonstrate its sensitivity to popular concern for the suffering of ordinary soldiers. This manifested in a highly publicized leaked letter from the Queen expressing her regard for ‘her troops’, the royal family’s visits to wounded soldiers, and the distribution of the Crimean Medal at a special ceremony, which portrayed the accessibility of the Queen through the use of touch. This article explores the symbolism and impetus of these occurrences and assesses the reception of royal intervention in the press. The few assessments of royal influence during the Crimean War have focused largely on Victoria’s personal fascination with the progress of the war and her soldiers. This article explores instead the wider, political significance of the army as extension of the royal family. The Liberal press and artists responded favourably to demonstrations of the Queen’s maternal sympathy for the troops, but my article will point to a hidden struggle to assert the Crown’s authority. Normal 0 false false false EN-GB X-NONE X-NONE

  13. The Case of the Royal School of Library and Information Science

    DEFF Research Database (Denmark)

    Borlund, Pia

    2010-01-01

    The present paper forms the basis of the invited talk to be given by the author at the International Symposium on the Transformation and Innovation of Library and Information Science, November 16-17, 2010, Taipei, Taiwan. The paper introduces the Royal School of Library and Information Science......, Denmark, as a European School of Library and Information Science and a member of iSchool Caucus. The paper outlines some of the current challenges of the Royal School of Library and Information Science and how these challenges are met, including how the membership of the iSchool movement is considered...

  14. Presidential addresses of the Royal Society of Tropical Medicine and Hygiene: 1907–2013

    Science.gov (United States)

    Hay, Simon I.; McHugh, Gerri M.

    2013-01-01

    Presidents have been required to give an inaugural address on commencing office at the Royal Society of Tropical Medicine and Hygiene (RSTMH) since its foundation in 1907. All presidential addresses were identified, sourced and assembled into an annotated bibliography. The majority of presidential addresses have been published in Transactions of the Royal Society of Tropical Medicine and Hygiene. Unpublished and in some cases ‘lost’ contributions have now been sourced where possible and archived at the RSTMH. This unique, rich and rewarding archive provides a vista into the development of the RSTMH and the discipline of tropical medicine. The archive is freely available to all. PMID:24026462

  15. The Role of the Royal Navy in Counter-Insurgency Campaigns since 1945

    OpenAIRE

    Guoth, Maroš

    2014-01-01

    The aim of this work is to prove that a navy can play an important role during a counter-insurgency campaign and be involved in many different tasks both at sea and from sea, particularly due to its flexibility, mobility and versatility. The main research question of the thesis is: what role can a navy play in a counter-insurgency campaign? The decision to focus on the role of the Royal Navy is based on the fact, that the Royal Navy is probably the most experienced navy in the world in the fi...

  16. Alternative sources of supplements for Africanized honeybees submitted to royal jelly production

    OpenAIRE

    Sereia, Maria Josiane; Toledo, Vagner de Alencar Arnaut de; Furlan, Antonio Claudio; Faquinello, Patrícia; Maia, Fabiana Martins Costa; Wielewski, Priscila

    2013-01-01

    This study was carried out to evaluate the effect of supplements with isolated soy protein, brewer's yeast, a mixture of isolated soy protein with brewer's yeast, linseed oil, palm oil and mixture of linseed oil with palm oil in the production of royal jelly by Africanized honeybee colonies. Total royal jelly production was higher (p < 0.05) in colonies fed with isolated soy protein and brewer's yeast (11.68 g colony-1), followed by linseed oil and palm oil (11.30 g colony-1) and palm oil (9....

  17. The Royal Treasury of the Kingdom of Majorca during the War of the Spanish Succession (1701-1715

    Directory of Open Access Journals (Sweden)

    Eduardo PASCUAL RAMOS

    2014-02-01

    Full Text Available The royal treasury of the kingdom of Majorca during the War of the Spanish Succession suffered an economic downturn caused mainly by its logistical contribution to the war. This article shows the evolution of the taxation carried out by the Royal Treasury of Majorca during the war, and is divided into three parts. The first one is a description of the Royal Treasury as an institution. The second one analyses revenues and expenses and shows the evolution of the institution’s finances during the conflict. The third part is a general inventory of the royal accounts during the war.

  18. Royal Ahold : A Failure of Corporate Governance and an Accounting Scandal

    NARCIS (Netherlands)

    de Jong, A.; DeJong, D.V.; Mertens, G.M.H.; Roosenboom, P.G.J.

    2005-01-01

    Royal Ahold (Koninklijke Ahold NV) was one of the major success stories in the 1990s and is one of the major failures, suffering a complete meltdown, in 2003.We investigate the strategy, accounting transparency and corporate governance of Ahold; elements which jointly drive the firm s performance

  19. Dr. Steve Thompson, Chief Executive, The Royal Society of New Zealand

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    L. to r.: Dr Austin Ball, Deputy Technical Coordinator, CMS experiment; Dr Roland Horisberger, Paul Scherrer Institute and CERN, CMS experiment; Dr Steve Thompson, Chief Executive, The Royal Society of New Zealand; Dr Michel Della Negra, Spokesman, CMS experiment and Dr Alick Macpherson, Paul Scherrer Institute and CERN, CMS experiment, in the CMS Silicon Tracker assembly hall.

  20. Delegation from the Royal Government and the Permanent Mission of Bhutan

    CERN Multimedia

    Patrice Loïez

    2003-01-01

    Photoa 01,02: Mr Yeshey Dorji, Chargé d'affaires, a. i., Permanent Mission of Bhutan in New York (3rd from left), visiting the ATLAS underground cavern with Dr Diether Blechschmidt, CERN Non-Member States Relations (4th from left) and Representatives of the Bhutan Royal Government and Permanent Mission in Geneva.

  1. Royal Service tegutseb üheksas riigis / Paavo Pilv ; interv. Eda-Liis Kann

    Index Scriptorium Estoniae

    Pilv, Paavo

    2004-01-01

    Äripäeva üritusturundusfirmade TOP-is I koha saavutanud Royal Service-i juht ettevõtte edukuse põhjustest, olulisematest töödest 2003. aastal, üritusturunduse tulevikutrendidest ja EL-iga liitumise mõjust valdkonna arengule

  2. The ICT-Integrated Pedagogy in the Colleges of Royal University of Bhutan

    DEFF Research Database (Denmark)

    Choeda, Par-Ola Zander; Penjor, Tandin; Dukpa, Dorji

    2014-01-01

    This paper reports a research study on the integration of ICT and pedagogy in the colleges of the Royal University of Bhutan. It investigates whether ICT is integrated into the pedagogy, and if so, in what way. The samples (Faculty members) of the study were picked up randomly from ten colleges u...

  3. Field Philosophy: Environmental Learning and Moral Development in Isle Royale National Park

    Science.gov (United States)

    Goralnik, Lissy; Nelson, Michael Paul

    2017-01-01

    We conducted a qualitative analysis of 5 years of student writing data to understand learning and moral development on a field philosophy course in Isle Royale National Park. We were interested in the connection between physical experiences in the natural world and the way students care about or value nonhuman beings, natural systems, and place.…

  4. Amateur Hour: Culture, Capital, and the Royal Shakespeare Company's Open Stages Initiative

    Science.gov (United States)

    Flynn, Molly

    2017-01-01

    In 2011, the Royal Shakespeare Company (RSC) began a series of collaborations with established amateur theatre groups from across the UK. The initiative now known as Open Stages became one of the most ambitious educational outreach programmes ever run by the RSC, engaging hundreds of amateur theatre practitioners in a process of skills sharing and…

  5. The Royal Entries of Henry VI in a London Civic Manuscript

    DEFF Research Database (Denmark)

    Bourassa, Kristin

    2016-01-01

    London Metropolitan Archives, MS Letter Book K, contains descriptions of Henry VI’s royal entries into both Paris (1431) and London (1432). Their placement one after the other in a London Letter Book was likely the work of the city’s common clerk, John Carpenter, who was the author of the descrip...

  6. Assessment of a number of compasses which contain radioactive paint, available from the Royal Airforce

    International Nuclear Information System (INIS)

    Aten, T.B.Th.

    1978-11-01

    There was a degree of uncertainty about the radiation safety of a number of compasses in use by the Dutch Royal Airforce and this has been investigated by the Medical Biological Laboratory of TNO. Four compasses have been examined and advice for their use, maintenance and repair is presented. (C.F.)

  7. Integrating Social Sustainability in Engineering Education at the KTH Royal Institute of Technology

    Science.gov (United States)

    Björnberg, Karin Edvardsson; Skogh, Inga-Britt; Strömberg, Emma

    2015-01-01

    Purpose: The purpose of this paper is to investigate what are perceived to be the main challenges associated with the integration of social sustainability into engineering education at the KTH Royal Institute of Technology, Stockholm. Design/methodology/approach: Semi-structured interviews were conducted with programme leaders and teachers from…

  8. Network Centric Warfare Concepts in the Royal Netherlands Army C2 Architecture

    NARCIS (Netherlands)

    Meijden, M.G. van der

    2004-01-01

    The Royal Netherlands Army (RNLA) has been working on its second generation C2 Information System since 2000. Its first generation Integrated Staff Information System (ISIS) that is currently deployed is based on ATCCIS specifications and uses the ATCCIS Replication Mechanism for database to

  9. APPARENT 85KRYPTON AGES OF GROUNDWATER WITHIN THE ROYAL WATERSHED, MAINE, USA

    Science.gov (United States)

    85Kr activities were determined in 264 domestic and municipal wells from 2002-2004 in the Royal watershed (361 km2), Maine. Gas extraction for 85Kr from wells was effected directly via a well-head methodology permitting efficient widespread analys...

  10. Description of Etrocorema belumensis sp.n. from Royal Belum State Park, Perak, Malaysia:

    OpenAIRE

    Asiah, Wan Nur; Salmah, Che M. R.; Sivec, Ignac

    2009-01-01

    Only one variable Etrocorema species, E. nigrogeniculatum (Enderlein), is currently recognized from Peninsular Malaysia. During limnological study in Royal Belum State Park, Malaysia, specimens of a new species of Etrocorema, E.belumensis n. sp., were discovered. Illustrations of male and female genitalia, eggs, and larvae of this new taxon are provided.

  11. Reflections on a Degree Initiative: The UK's Birmingham Royal Ballet Dancers Enter the University of Birmingham

    Science.gov (United States)

    Benn, Tansin

    2003-01-01

    This paper provides an opportunity to share experiences and perceptions of the first 5 years of a degree programme for professional dancers. A partnership developed in the mid-1990s between the UK's Birmingham Royal Ballet and the University of Birmingham, Westhill (now School of Education), to provide a part-time, post-experience, flexible study…

  12. A Member of Complementary Medicinal Food: Anatolian Royal Jellies, Their Chemical Compositions, and Antioxidant Properties.

    Science.gov (United States)

    Kolayli, Sevgi; Sahin, Huseyin; Can, Zehra; Yildiz, Oktay; Malkoc, Meltem; Asadov, Alsever

    2016-10-01

    This study investigated various chemical and antioxidant properties of Anatolian royal jelly samples. Moisture, pH, total protein, 10-hydroxy-2-decenoic acid (10-HDA) and sugars were analyzed from 18 samples. Total phenolic contents, ferric reducing antioxidant capacity and 2,2-diphenyl-1-picryhydrazyl (DPPH) free radical scavenging activity were measured as antioxidant determinants. 10-HDA contents and total protein content of fresh weight ranged between 1.0% and 3.9%, and 11.4% and 15.8%, respectively. The main sugars detected were glucose and fructose. Maltose, trehalose, and melibiose were detected at less than 1.0% in all samples. Lactose, a milk sugar, was detected in only 3 samples, at values between 0.8% and 1.4%. Total henolic content ranged from 91.0 to 301.0 mg gallic acid equivalents/kg fresh weight. Antioxidant activity is due to both to the total phenolic content, proteins and fatty acids of royal jelly. Anatolian royal jelly samples were not different from other royal jelly samples from across the world. © The Author(s) 2015.

  13. Depression riots and the calling of the 1897 West India Royal Commission

    Directory of Open Access Journals (Sweden)

    Bonham C. Richardson

    1992-07-01

    Full Text Available Questions why the West India Royal Commission of 1897 was considered necessary when serious distress already existed in the 1880s. Author argues that riots caught the government's attention much more readily than statistical data. Even minor disturbances could have distracted London from its preoccupation with the newer, more important parts of the Empire.

  14. Hospital Compare

    Data.gov (United States)

    U.S. Department of Health & Human Services — Hospital Compare has information about the quality of care at over 4,000 Medicare-certified hospitals across the country. You can use Hospital Compare to find...

  15. HCAHPS - Hospital

    Data.gov (United States)

    U.S. Department of Health & Human Services — A list of hospital ratings for the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS). HCAHPS is a national, standardized survey of hospital...

  16. Condensation system with seawater in the Royal Solaris Hotel of Cancun; Sistema de condensacion con agua salada en el hotel Royal Solaris de Cancun

    Energy Technology Data Exchange (ETDEWEB)

    Herrero, Juan F.; Hernandez A, David [Celsol, S.A. de C.V., Nuevo Leon (Mexico)

    1999-07-01

    After performing a technical study, during the month of September of 1998, in the facilities of Villas Solaris, S.A. de C.V., specifically in the Royal Solaris Hotel, towers Royal and Caribe, important opportunities of saving were found, which were evaluated technical and economically to be able to present to Villa Solaris, S.A. of C.V., an energy saving project highly profitable that allows to obtain great economic benefits, a better service for the hosts and an important step to the reduction of the operative expenses (energy), that guaranteed the future competitiveness of the hotel in the zone. The base of the energy saving opportunities is the substitution of the air conditioning equipment, since the installed ones in the Hotel, are very deficient equipment (piston in Caribbean Tower) or because of by International ecological Norms they will be obsolete in short time (centrifugal R-11 Torre Royal). In addition the service machine area of the Hotel was centralized in a single site. The substitution measure of the air conditioning systems, contemplated the installation of centrifugal equipment of high efficiency (0.65kW/Ton at full load) cooled with brackish water, that is a very abundant resource in the zone and does not represent any cost for the Hotel. The waste heat of the refrigeration machines is contemplated to be used to preheat the service water and the swimming pool water by means of heat exchange equipment. In order to arrive to the desired optimal temperatures the advantage of the installation of the already existing in the Hotel thermo solar systems was taken into consideration. When implementing this global system, the use of cooling towers was eliminated, that was the equipment that cools the condensation water of the air conditioning equipment. In addition the use of the steam boilers was eliminated that made the function of warming up the service water, reason why an important saving of fuel was generated. [Spanish] Despues de haber realizado un

  17. Anti-inflammatory effects of royal jelly on ethylene glycol induced renal inflammation in rats

    Directory of Open Access Journals (Sweden)

    Zeyneb Aslan

    2015-10-01

    Full Text Available ABSTRACT Objective: In this study, anti-inflammatory effects of Royal Jelly were investigated by inducing renal inflammation in rats with the use of ethylene glycol. For this purpose, the calcium oxalate urolithiasis model was obtained by feeding rats with ethylene glycol in drinking water. Materials and Methods: The rats were divided in five study groups. The 1st group was determined as the control group. The rats in the 2nd group received ethylene glycol (1% in drinking water. The rats in the 3rd group were daily fed with Royal Jelly by using oral gavage. The 4th group was determined as the preventive group and the rats were fed with ethylene glycol (1% in drinking water while receiving Royal Jelly via oral gavage. The 5th group was determined as the therapeutic group and received ethylene glycol in drinking water during the first 2 weeks of the study and Royal Jelly via oral gavage during the last 2 weeks of the study. Results: At the end of the study, proinflammatory/anti-inflammatory cytokines, TNF-α, IL-1β and IL-18 levels in blood and renal tissue samples from the rats used in the application were measured. Conclusion: The results have shown that ethylene glycol does induce inflammation and renal damage. This can cause the formation of reactive oxygen species. Royal Jelly is also considered to have anti-inflammatory effects due to its possible antiradical and antioxidative effects. It can have positive effects on both the prevention of urolithiasis and possible inflammation during the existing urolithiasis and support the medical treatment.

  18. Hospital discharge summary scorecard: a quality improvement tool used in a tertiary hospital general medicine service.

    Science.gov (United States)

    Singh, G; Harvey, R; Dyne, A; Said, A; Scott, I

    2015-12-01

    We assessed the impact of completion and feedback of discharge summary scorecards on the quality of discharge summaries written by interns in a general medicine service of a tertiary hospital. The scorecards significantly improved summary quality in the first three rotations of the intern year and could be readily adopted by other units as a quality improvement intervention for optimizing clinical handover to primary care providers. © 2015 Royal Australasian College of Physicians.

  19. The Effects of Royal Jelly on In-Vitro Cytotoxicity of K562 Cells and Peripheral Blood Mononuclear Cells

    Directory of Open Access Journals (Sweden)

    SE Hosseini

    2014-02-01

    Full Text Available Abstract Background & aim: Royal jelly, secreted by worker bees, has different biological activities on cells and tissues. The aim of this study was to evaluate the effects of royal jelly on peripheral blood mononuclear cells and on the tumor category of K562 cell line. Methods: In the present experimental study, three subjects were selected separately with three repetitions. K562 (104 cells and PBMC (105 cells with different concentrations of royal jelly (5, 10, 25, 50 and 100 mg/ml were cultured under standard conditions for 48 and 72 h separately. The fatality rate on PBMC cells and K562 cancer cells was evaluated by using MTT (Tetrazolium Dye-Reduction Assay. The number of viable cells in PBMC that were exposed for 48 hours with Royal Jelly was evaluated by trypan blue staining. Data were analyzed by ANOVA. Results: The royal jelly had no cytotoxicity effect on PBMC cells but at concentration of 50 and 100 mg/mL the cytotoxicity effect were observed on k562 cells whereas, at 10 and 25 mg/ml the number of PBMC viable cells increased. Conclusion: Due to the lack of lethality of royal jelly on PBMC cells and PBMC cell viability and an increase in the fatality rate of cancer cells in the future, royal jelly can be used as a potential candidate for treatment of leukemia. Keywords: Royal jelly, K562, peripheral blood mononuclear cell

  20. Determination of (2E-10-hydroxydec-2-enoic acid in Croatian royal jelly by high-performance liquid chromatography

    Directory of Open Access Journals (Sweden)

    Ivana Flanjak

    2017-01-01

    Full Text Available Although health-promoting properties of royal jelly are known for many years, the absence of quality standards and methods prescribed for their determination leads to royal jelly adulteration. Royal jelly is a source of unique unsaturated fatty acid, (2E-10-hydroxydec-2-enoic acid (10-HDA, and its content is considered as one of the freshness and authenticity parameter. In this study, high performance liquid chromatographic method (HPLC with UV detection was validated and 10-HDA content in fresh royal jelly samples produced in Eastern Croatia was determined. The data about Croatian royal jelly are not available, therefore the results presented in this study could be considered as pioneer results for Croatian royal jelly characterization in respect of the 10-HDA. Method performance characteristics showed that the used method is fit for purpose. The content of 10-HDA in analysed samples varied from 1.56% up to 3.78%. According to the international recommendations for royal jelly quality, samples were fresh and authentic regarding 10-HDA content. Furthermore, the effect of packaging material on 10-HDA content was observed. Based on the obtained results, the conclusion was reached that if the samples were collected at the same time and frozen after collection, collection and storage of fresh royal jelly in glass and plastic containers had no effect on 10-HDA content.

  1. Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the treatment of eating disorders.

    Science.gov (United States)

    Hay, Phillipa; Chinn, David; Forbes, David; Madden, Sloane; Newton, Richard; Sugenor, Lois; Touyz, Stephen; Ward, Warren

    2014-11-01

    This clinical practice guideline for treatment of DSM-5 feeding and eating disorders was conducted as part of the Royal Australian and New Zealand College of Psychiatrists (RANZCP) Clinical Practice Guidelines (CPG) Project 2013-2014. The CPG was developed in accordance with best practice according to the National Health and Medical Research Council of Australia. Literature of evidence for treatments of anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), other specified and unspecified eating disorders and avoidant restrictive food intake disorder (ARFID) was sourced from the previous RANZCP CPG reviews (dated to 2009) and updated with a systematic review (dated 2008-2013). A multidisciplinary working group wrote the draft CPG, which then underwent expert, community and stakeholder consultation, during which process additional evidence was identified. In AN the CPG recommends treatment as an outpatient or day patient in most instances (i.e. in the least restrictive environment), with hospital admission for those at risk of medical and/or psychological compromise. A multi-axial and collaborative approach is recommended, including consideration of nutritional, medical and psychological aspects, the use of family based therapies in younger people and specialist therapist-led manualised based psychological therapies in all age groups and that include longer-term follow-up. A harm minimisation approach is recommended in chronic AN. In BN and BED the CPG recommends an individual psychological therapy for which the best evidence is for therapist-led cognitive behavioural therapy (CBT). There is also a role for CBT adapted for internet delivery, or CBT in a non-specialist guided self-help form. Medications that may be helpful either as an adjunctive or alternative treatment option include an antidepressant, topiramate, or orlistat (the last for people with comorbid obesity). No specific treatment is recommended for ARFID as there are no trials to

  2. Sir William Burnett (1779-1861), professional head of the Royal Naval Medical Department and entrepreneur.

    Science.gov (United States)

    Penn, Christopher

    2004-08-01

    Sir William Burnett (1779-1861) had an active career as a Royal Navy surgeon in the French Revolutionary and Napoleonic Wars, including service at the battles of St Vincent, the Nile and Trafalgar. From 1822 to 1855 he was professional head of the Royal Naval Medical Department, when he provided effective leadership in a time of great change. Although his official work earned him the reputation of a "hard-working, unimaginative, somewhat harsh man", his correspondence shows a very humane centre under the official carapace. His official performance and reputation were both eroded towards the end of his career by his determined promotion of zinc chloride, for which he held lucrative patents.

  3. The zoonotic implications of pentastomiasis in the royal python (python regius).

    Science.gov (United States)

    Ayinmode, Ab; Adedokun, Ao; Aina, A; Taiwo, V

    2010-09-01

    Pentastomes are worm-like endoparasites of the phylum Pentastomida found principally in the respiratory tract of reptiles, birds, and mammals. They cause a zoonotic disease known as pentastomiasis in humans and other mammals. The autopsy of a Nigerian royal python (Python regius) revealed two yellowish-white parasites in the lungs, tissue necrosis and inflammatory lesions. The parasite was confirmed to be Armillifer spp (Pentastomid); this is the first recorded case of pentastomiasis in the royal python (Python regius) in Nigeria. This report may be an alert of the possibility of on-going zoonotic transmission of pentastomiasis from snake to man, especially in the sub-urban/rural areas of Nigeria and other West African countries where people consume snake meat.

  4. Action Stations! 100 years of trauma care on maritime and amphibious operations in the Royal Navy.

    Science.gov (United States)

    Osborne, M; Smith, J E

    2015-01-01

    Over the past century trauma care within the Royal Navy (RN) has evolved; wartime experiences and military medical research have combined to allow significant improvement in the care of casualties. This article describes the key maritime and amphibious operations that have seen the Royal Navy Medical Service (RNMS) deliver high levels of support to wherever the Naval Service has deployed in the last 100 years. Key advancements in which progress has led to improved outcomes for injured personnel are highlighted--the control and treatment of blood loss, wound care, and the prevention and management of organ failure with optimal resuscitation. Historians often point out how slowly military medicine progressed for the first few thousand years of its recorded history, and how quickly it has progressed in the last century. This reflective article will show how the RNMS has been an integral part of that story, and how the lessons learnt by our predecessors have shaped our modern day doctrine surrounding trauma care.

  5. PHOTOGRAMMETRIC AND LIDAR DOCUMENTATION OF THE ROYAL CHAPEL (CATHEDRAL-MOSQUE OF CORDOBA, SPAIN

    Directory of Open Access Journals (Sweden)

    J. Cardenal

    2012-07-01

    Full Text Available At present, cultural heritage documentation projects use a variety of spatial data acquisition techniques such as conventional surveying, photogrammetry and terrestrial laser scanning. This paper deals with a full documentation project based on all those techniques in the Royal Chapel located in the Cathedral-Mosque of Cordoba in Spain, declared World Heritage Site by UNESCO. At present, the Royal Chapel is under study for a detailed diagnostic analysis in order to evaluate the actual state of the chapel, pathologies, construction phases, previous restoration works, material analysis, etc. So in order to assist the evaluation, a documentation project with photogrammetric and laser scanner techniques (TLS has been carried out. With this purpose, accurate cartographic and 3D products, by means of the integration of both image and laser based techniques, were needed to register all data collected during the diagnostic analysis.

  6. Observing the skies of Lisbon. Isaac de Sequeira Samuda, an estrangeirado in the Royal Society.

    Science.gov (United States)

    Vieira, Carla Costa

    2014-06-20

    Elected in 1723, Isaac de Sequeira Samuda (1681-1729) was the first Jewish Fellow of the Royal Society. He had arrived in London just a few years earlier, escaping from the Portuguese Inquisition. Despite his past, he had no difficulty in establishing links with his country's diplomatic representatives in London. A physician and adviser on scientific subjects, he became a conduit between the emerging world of Portuguese astronomy and the British scientific community. He reported to the Royal Society on astronomical observations made in the new observatories in Lisbon and helped with the acquisition of scientific instruments and books destined for Portugal. These activities were facets of Samuda's unusual career and the diverse though often converging associations that he established until his death. As the member of a network active in the diffusion of new ideas and in the modernization of Portuguese science, Samuda can be regarded as an estrangeirado, as this term has come to be used in the modern literature.

  7. Structural diagnosis of historic timber structures: the Diplomatic Room of the of Royal Palace of Naples

    Directory of Open Access Journals (Sweden)

    Donato Calicchio

    2012-12-01

    Full Text Available The aim of this article is to describe the diagnosis process made on the timber structure that holds up the vault of the Diplomatic Room of the Royal Palace in Naples (Italy. After a brief historical description of the Royal Palace and the Diplomatic Room, it discusses the methodology according to Italian regulations and the speci­fic problems that arose during the works. To complete the diagnosis, a dendrochronological analysis of the wooden elements was performed. The results show the residual mechanical properties of each structural element and the main problems to be resolved by the restorers. The dendrochronological conclusions yield that the dating of the elements is compatible with that of the frescoes on the vault and therefore demonstrate that the elements have not been replaced.

  8. Identification of genes related to high royal jelly production in the honey bee (Apis mellifera) using microarray analysis.

    Science.gov (United States)

    Nie, Hongyi; Liu, Xiaoyan; Pan, Jiao; Li, Wenfeng; Li, Zhiguo; Zhang, Shaowu; Chen, Shenglu; Miao, Xiaoqing; Zheng, Nenggan; Su, Songkun

    2017-01-01

    China is the largest royal jelly producer and exporter in the world, and high royal jelly-yielding strains have been bred in the country for approximately three decades. However, information on the molecular mechanism underlying high royal jelly production is scarce. Here, a cDNA microarray was used to screen and identify differentially expressed genes (DEGs) to obtain an overview on the changes in gene expression levels between high and low royal jelly producing bees. We developed a honey bee gene chip that covered 11,689 genes, and this chip was hybridised with cDNA generated from RNA isolated from heads of nursing bees. A total of 369 DEGs were identified between high and low royal jelly producing bees. Amongst these DEGs, 201 (54.47%) genes were up-regulated, whereas 168 (45.53%) were down-regulated in high royal jelly-yielding bees. Gene ontology (GO) analyses showed that they are mainly involved in four key biological processes, and pathway analyses revealed that they belong to a total of 46 biological pathways. These results provide a genetic basis for further studies on the molecular mechanisms involved in high royal jelly production.

  9. Identification of genes related to high royal jelly production in the honey bee (Apis mellifera using microarray analysis

    Directory of Open Access Journals (Sweden)

    Hongyi Nie

    2017-10-01

    Full Text Available Abstract China is the largest royal jelly producer and exporter in the world, and high royal jelly-yielding strains have been bred in the country for approximately three decades. However, information on the molecular mechanism underlying high royal jelly production is scarce. Here, a cDNA microarray was used to screen and identify differentially expressed genes (DEGs to obtain an overview on the changes in gene expression levels between high and low royal jelly producing bees. We developed a honey bee gene chip that covered 11,689 genes, and this chip was hybridised with cDNA generated from RNA isolated from heads of nursing bees. A total of 369 DEGs were identified between high and low royal jelly producing bees. Amongst these DEGs, 201 (54.47% genes were up-regulated, whereas 168 (45.53% were down-regulated in high royal jelly-yielding bees. Gene ontology (GO analyses showed that they are mainly involved in four key biological processes, and pathway analyses revealed that they belong to a total of 46 biological pathways. These results provide a genetic basis for further studies on the molecular mechanisms involved in high royal jelly production.

  10. The Avaldsnes Royal Manor Project’s Research Plan and Excavation Objectives

    OpenAIRE

    Skre, Dagfinn

    2017-01-01

    This chapter provides an outline of the scholarly problems that the Avaldsnes Royal Manor Project was designed to address, the central theme explored being the political institutions and processes in the first millennium AD. The research plan was developed during the 2007–9 pilot project phase, and was adjusted and supplemented during the 2011–12 excavations and the research and publication phase in the subsequent years. The first of the research plan’s two sections, the results of which are ...

  11. The Phenotypic Effects of Royal Jelly on Wild-Type D. melanogaster Are Strain-Specific

    OpenAIRE

    Morgan, Stefanie L.; Seggio, Joseph A.; Nascimento, Nara F.; Huh, Dana D.; Hicks, Jasmin A.; Sharp, Katherine A.; Axelrod, Jeffrey D.; Wang, Kevin C.

    2016-01-01

    The role for royal jelly (RJ) in promoting caste differentiation of honeybee larvae into queens rather than workers is well characterized. A recent study demonstrated that this poorly understood complex nutrition drives strikingly similar phenotypic effects in Drosophila melanogaster, such as increased body size and reduced developmental time, making possible the use of D. melanogaster as a model system for the genetic analysis of the cellular mechanisms underlying RJ and caste differentiatio...

  12. Serving the medicinal chemistry community with Royal Society of Chemistry cheminformatics platforms

    OpenAIRE

    Williams, Antony

    2015-01-01

    The Royal Society of Chemistry (RSC) is a major participant in providing access to chemistry related data via the web. As an internationally renowned society for the chemical sciences, a scientific publisher and the host of the ChemSpider database for the community, RSC continues to make dramatic strides in providing online access to data. ChemSpider provides access to over 30 million chemicals sourced from over 500 data suppliers and linked out to related information on the web. The platform...

  13. The Zoonotic Implications of Pentastomiasis in the Royal Python (Python Regius)

    OpenAIRE

    Ayinmode, AB; Adedokun, AO; Aina, A; Taiwo, V

    2010-01-01

    Pentastomes are worm-like endoparasites of the phylum Pentastomida found principally in the respiratory tract of reptiles, birds, and mammals. They cause a zoonotic disease known as pentastomiasis in humans and other mammals. The autopsy of a Nigerian royal python (Python regius) revealed two yellowish-white parasites in the lungs, tissue necrosis and inflammatory lesions. The parasite was confirmed to be Armillifer spp (Pentastomid); this is the first recorded case of pentastomiasis in the r...

  14. The William Houston Medal of the Royal College of Surgeons of Edinburgh 2002.

    Science.gov (United States)

    Teague, A M

    2004-06-01

    The William Houston medal is a prestigious prize awarded to the individual achieving the most outstanding examination performance at the Membership in Orthodontics examination for the Royal College of Surgeons of Edinburgh. Five clinical cases treated by the candidate are presented as part of the final examination; two of these cases are described below. The first a Class III malocclusion, and the second a Class II division 1 malocclusion, were both treated by orthodontic camouflage.

  15. Royal Observatory extension will teach the wonder of the night sky

    CERN Multimedia

    Jury, L

    2004-01-01

    "The Royal Observatory in Greenwich is gearing up for a massive pounds 15m extension next year, to capitalise on growing interest in outer space. A Victorian building which has been used for administration for decades is to be renovated, with new galleries and a 120-seat planetarium to treble the space for visitors to gaze at the stars. The Observatory hopes to complete the extension by 2007" (1 page).

  16. Royal Order of 28 March 1969 listing occupational diseases giving rise to compensation

    International Nuclear Information System (INIS)

    1969-01-01

    This Royal Order, made in implementation of the Act of 24 December 1963 on compensation for damage resulting from occupational diseases and prevention thereof, as amended by an Act fo 24 December 1968, lists the occupational diseases giving rise to compensation and includes those caused by ionizing radiations. The Order came into force on 1 July 1969 and repealed a previous Order of 18 January 1964 which laid down a first list of such diseases giving rise to compensation. (NEA) [fr

  17. Resource recovery. A report for the Royal Commission of Environmental Pollution

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    A report for the Royal Commission on Environmental Pollution describes the key factors influencing the level of resource recovery in the UK and compares the level in other European countries and the US. Aspects covered include waste paper, oils and batteries, cost allocation, waste disposal cost and charges, separation of waste streams and energy from waste. Finally the report identifies a number of specific areas where action might be taken to increase resource recovery. (UK).

  18. Making public ahead of print: Meetings and publications at the Royal Society, 1752?1892

    OpenAIRE

    Fyfe, Aileen; Moxham, Noah

    2016-01-01

    This essay examines the interplay between the meetings and publications of learned scientific societies during the eighteenth and nineteenth centuries, when journals were an established but not yet dominant form of scholarly communication. The practice of ‘making public’ research at meetings, long before actual ‘publication’ in society periodicals, enabled a complex of more-or-less formal sites of communication and discussion ahead of print. Using two case studies from the Royal Society of Lo...

  19. Ground water for public water supply at Windigo, Isle Royale National Park, Michigan

    Science.gov (United States)

    Grannemann, N.G.; Twenter, F.R.

    1982-01-01

    Three test holes drilled at Windigo in Isle Royale National Park in 1981 indicate that the ophitic basaltic lava flows underlying the area contain little water and cannot be considered a source for public water supply. The holes were 135, 175, and 71 feet deep. One hole yielded about 1 gallon of water perminute; the other two yielded less. Glacial deposits seem to offer the best opportunity for developing a ground-water supply of 5 to 10 gallons per minute.

  20. Informing Royal Navy People Strategy: Understanding Career Aspirations and Behaviours of Naval Personnel

    OpenAIRE

    Bewley, Elizabeth Emma; Royal Navy (Great Britain); Ministry of Defence (Great Britain)

    2016-01-01

    Following a series of imposed redundancies in the Royal Navy (RN) there was a need to understand the career desires of remaining personnel and how these interact with important organisational behaviours and turnover. Taking a social psychology perspective, this thesis addresses criticisms over the high use of non-working populations in research and provides the first empirical evidence for the utility, applicability and relevance of specific psychological theories to the RN. Chapter 2 explore...

  1. Readability and the Production of Instructional Text in the Royal Navy,

    Science.gov (United States)

    1980-11-01

    images became blurred. A finding of particular irrpor- tance for the Royal Navy was by Brand et al [6]. They found that the actual movemnt or rotion of a...Organisation 3. Headings 4. Typography 5. Clarity of words 6. Questions 7. Clarity of structure 8. Complex material 9. Illustrations 10. Colour 11...Illustrations, Tables, Graphs and Charts. (Hartley 1978) - 6B - 4. Typography Legibility is the most important factor in the printed page. Before any significance

  2. Effect of Royal Jelly on Improving Passive Avoidance Learning and Spatial Learning and Memory in Rats

    Directory of Open Access Journals (Sweden)

    H Alaei

    2012-06-01

    Full Text Available Introduction: Studies have proposed that royal jelly(RJ has various biological activities in different cells and tissues. Since it has been demonstrated that RJ contains compounds having desirable effects on central neurons system and neural functions, the present study aimed to investigate the effect of royal jelly on learning and memory in rats. Methods: Male wistar rats were divided into two groups, the royal jelly and the control. In the RJ group, the rats received a food that contained 3% RJ instead of regular food for 10 days. Then learning and memory were investigated in these animals through both passive avoidance learning test(1 day and 1 week after receiving electrical shock and Morris water maze test(1 day and 1 week after a 4-day learning period. Results: The study results indicated that the food containing RJ in the RJ group significantly increased the time of the first entrance to the dark room one week after the electrical shock in passive avoidance learning test. In other words, the findings suggest an improvement of learning and memory in RJ group. In the acquisition phase of Morris water maze test, rats receiving RJ found the underwater escape plate during less time and distance comparing with the control group. Furthermore, one week after the acquisition phase, in the retention phase, rats spent more time in the quadrant in which the escape plate was previously located. Conclusion: The present study findings propose that Royal Jelly can improve cognitive processes through positive effects on neural functions and probably has a significant influence on prevention and therapy of some neuronal disorders.

  3. Incidence of Boxing Injuries in the Royal Air Force in the United Kingdom 1953—66

    Science.gov (United States)

    Brennan, T. N. N.; O'Connor, P. J.

    1968-01-01

    Statistics of injuries arising in amateur boxing in the Royal Air Force in the 14 years 1953-66 are given. There were 240 injuries including two deaths in the 14 years. During the seven years 1960-66, four men out of every thousand entering the ring received injuries to the head or neck which kept them off work for 48 hours or more. No case of the punch-drunk syndrome was seen. PMID:5723355

  4. The factors that influence job satisfaction among royal Malaysian customs department employee

    Science.gov (United States)

    Ammar Shafi, Muhammad; Saifullah Rusiman, Mohd; Nor, Maria Elena; Khamis, Azme; Nabilah Syuhada Abdullah, Siti; Syafiq Azmi, Mohd; Sakinah Zainal Abidin, Munirah; Ali, Maselan

    2018-04-01

    This research aims to spot the factors that influence job satisfaction among Royal Malaysian Customs Department employees. Primary data was used in this research and it was collected from the employees who work in five different departments at Royal Malaysian Customs Department Tower Johor. Those departments were customs department, Internal Taxes, Technical Services, Management and Prevention. The research used stratified random sampling to collect the sample and Structural Equation Modelling (SEM) to measure the relationship between variables using AMOS software. About 127 employees are selected as the respondents from five departments to represent the sample. The result showed that ‘Organizational Commitment’ (p-value = 0.001) has significant and direct effect toward job satisfaction compared to the ‘Stress Condition’ (p-value = 0.819) and ‘Motivation’ factor (p-value = 0.978). It was also concluded that ‘Organizational Commitment’ was the most influential factor toward job satisfaction among Royal Malaysian Customs Department employees at Tower Custom Johor, Johor Bahru.

  5. Evaluation and review of the safety management system implementation in the Royal Thai Air Force

    Science.gov (United States)

    Chaiwan, Sakkarin

    This study was designed to determine situation and effectiveness of the safety management system currently implemented in the Royal Thai Air Force. Reviewing the ICAO's SMS and the RTAF's SMS was conducted to identify similarities and differences between the two safety management systems. Later, the researcher acquired safety statistics from the RTAF Safety Center to investigate effectiveness of its safety system. The researcher also collected data to identify other factors affecting effectiveness of the safety system during conducting in-depth interviews. Findings and Conclusions: The study shows that the Royal Thai Air Force has never applied the International Civil Aviation Organization's Safety management System to its safety system. However, the RTAF's SMS and the ICAO's SMS have been developed based on the same concepts. These concepts are from Richard H. Woods's book, Aviation safety programs: A management handbook. However, the effectiveness of the Royal Thai Air Force's safety system is in good stance. An accident rate has been decreasing regularly but there are no known factors to describe the increasing rate, according to the participants' opinion. The participants have informed that there are many issues to be resolved to improve the RTAF's safety system. Those issues are cooperation among safety center's staffs, attitude toward safety of the RTAF senior commanders, and safety standards.

  6. PENDELEGASIAN TUGAS KEPADA TRAINEE DI MAIN KITCHEN GRAND ROYAL PANGHEGAR HOTEL BANDUNG

    Directory of Open Access Journals (Sweden)

    Asep Rijwan

    2016-03-01

      Abstrak - Masalah yang di teliti adalah bagaimana pendelegasian tugas kepadatraineedi main kitchen, bagaimana standar operasional prosedur pendelegasian tugas kepada trainee di main kitchen, serta bagaimana kesempatan dan peluang dari pendelegasian tugas kepada trainee di main kitchen.  Dalam hal pengolahan data, penulis menggunakan analisis deskriptif, yaitu metode yang berusaha mengumpulkan data dan sesuai dengan keadaan yang sebenarnya, menyajikan serta menganalisanya sehigga dapat memberikan gambaran yang cukup jelas atas objek yang diteliti dan kemudian di ambil kesimpulannya. Berdasarkan hasil observasi ini dapat disimpulkan bahwa pendelegasian tugas kepada trainee di Main Kitchen Grand Royal Panghegar Hotel sudah dilaksanakan dengan sangat baik, hal ini dapat dilihat dengan di selesaikannya delegasi tugas dengan baik pula oleh trainee. Standar operasional prosedur pendelegasian kepada trainee di Main Kitchen Grand Royal Panghegar Hotel sudah baik, hal ini dapat dilihat bahwa trainee dapat melaksanakan kegiatan- kegiatan yang ada di main kitchen dengan baik pula. Peluang dari pendelegasian tugas kepada trainee di Main Kitchen Grand Royal Panghegar Hotel menjadikan trainee lebih percaya diri, memiliki pengalaman baru dalam mengolah makanan, lebih meningkatnya skill trainee, dan memiliki pengetahuan yang lebih dari sebelumnya, dan staff pun tidak akan mendapat terlalu banyak beban pekerjaan, karena sebagian dapat dikerjakan oleh trainee dengan baik. Berdasarkan dari hasil observasi dan pembahasan tersebut, penulis menyimpulkan bahwa apabila standar operasional prosedur pendelegasian kepada Trainee dijalankan dengan baik, maka selain berdampak baik kepada trainee akan berdampak baik pula kepada staff atau hotel itu sendiri.

  7. The Australian Royal Commission into Institutional Responses to Child Sexual Abuse: Dreaming of Child Safe Organisations?

    Directory of Open Access Journals (Sweden)

    William Budiselik

    2014-09-01

    Full Text Available On 12 November 2012 the then Australian Prime Minister Julia Gillard announced she was recommending to the Governor General the establishment of a Royal Commission into Institutional Responses to Child Sexual Abuse. Following inquiries in Australia and elsewhere much is already known about institutional and inter-institutional child protection failures and what is required to address them. That Australia’s national government has pursued another abuse inquiry with terms of reference limited to institution-based (excluding the family sexual abuse is of interest given the lack of political will to enact previous findings and recommendations. This article examines the background to the Government’s announcement, the Commission’s terms of reference and some of its settings, and literature on the nature of royal commissions across time and place. After the lack of success in implementing the recommendations of previous inquiries into how to better protect Australia’s children, the question is: how will this Royal Commission contribute to Australian child protection and safety? Will the overwhelming public support generated by “truth speaking to power” in calling for this inquiry translate into action?

  8. The Australian Royal Commission into Institutional Responses to Child Sexual Abuse.

    Science.gov (United States)

    Wright, Katie; Swain, Shurlee; McPhillips, Kathleen

    2017-12-01

    The Royal Commission into Institutional Responses to Child Sexual Abuse is the largest royal commission in Australia's history and one of the largest public inquiries into institutional child abuse internationally. With an investment from the Australian government of half a billion dollars, it examined how institutions with a responsibility for children, both historically and in the present, have responded to allegations of child sexual abuse. Announced in the wake of previous Australian and international inquiries, public scandals and lobbying by survivor groups, its establishment reflected increasing recognition of the often lifelong and intergenerational damage caused by childhood sexual abuse and a strong political commitment to improving child safety and wellbeing in Australia. This article outlines the background, key features and innovations of this landmark public inquiry, focusing in particular on its extensive research program. It considers its international significance and also serves as an introduction to this special edition on the Australian Royal Commission, exploring its implications for better understanding institutional child sexual abuse and its impacts, and for making institutions safer places for children in the future. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  9. In the Service of the King. Concerning Royal Diplomatic Letters in the Crown of Aragon (1336-1458

    Directory of Open Access Journals (Sweden)

    María Luz Mandingorra Llavata

    2017-12-01

    Full Text Available The aim of this paper is to reconstruct the morphological evolution of the royal diplomatic letter in the Crown of Aragon between the reigns of Peter the Ceremonious and Alfonso the Magnanimous. During this period, the form taken by this document was adapted to its contents and those in receipt of it, according to the principles of the Ars dictaminis, without relinquishing its material and textual simplicity in the process. With its adaptation to the communicative requirements of the monarchy, the royal diplomatic letter became an instrument of governance that helped to strengthen royal power and anticipated mechanisms that would be fully developed during the Early Modern Period.

  10. Reseña de: Aguiar Andrade, Amélia y Millán da Costa, Adelaide (Eds. La ville Médiévale en Débat. Instituto de Estudos Medievais, Lisboa, 2013, 206 páginas (Estudos, 8, (Idiomas Francés, Español e Inglés. ISBN: 978-989-97066-9-9.

    Directory of Open Access Journals (Sweden)

    Ana María Rivera Medina

    2017-05-01

    Full Text Available Aguiar Andrade, Amélia y Millán da Costa, Adelaide (Eds. La ville Médiévale en Débat. Instituto de Estudos Medievais, Lisboa, 2013, 206 páginas (Estudos, 8, (Idiomas Francés, Español e Inglés. isbn: 978-989-97066-9-9.

  11. Canine Supply for Physical Security: An Analysis of the Royal Australian Air Force Military Working Dog Program

    Science.gov (United States)

    2016-03-01

    PHYSICAL SECURITY: AN ANALYSIS OF THE ROYAL AUSTRALIAN AIR FORCE MILITARY WORKING DOG PROGRAM by Mark W. Powell March 2016 Thesis...AN ANALYSIS OF THE ROYAL AUSTRALIAN AIR FORCE MILITARY WORKING DOG PROGRAM 5. FUNDING NUMBERS 6. AUTHOR(S) Mark W. Powell 7. PERFORMING...increased demand on its physical security elements. Its military working dog (MWD) workforce is required to meet an inventory of 204 by end of year 2023 as

  12. Hospital staffing and hospital costs.

    Science.gov (United States)

    Andrew, R R

    1976-08-07

    A comparative study of costs per bed per day in teaching hospitals affiliated with Monash University compared with large non-teaching metropolitan hospitals (1964 to 1974) shows they are much higher in teaching hospitals. There is no evidence that this is due to the additional costs arising from the clinical schools. Research in the teaching hospitals and the accompanying high professional standards and demands on services are major factors accounting for the difference. Over the decade studied, the resident staff have increased by 77% and other salaried staff by 24%. The index of expenditure for the three teaching hospitals in the decade has increased by 386%.

  13. Effect of royal jelly ingestion for six months on healthy volunteers

    Directory of Open Access Journals (Sweden)

    Morita Hiroyuki

    2012-09-01

    Full Text Available Abstract Background Royal jelly is a widely ingested supplement for health, but its effects on humans are not well known. The objective was to evaluate the effects of long-term royal jelly ingestion on humans. Methods We conducted a randomized placebo-controlled, double-blind trial. A total of 61 healthy volunteers aged 42-83 years were enrolled and were randomly divided into a royal jelly group (n = 31 and a control group (n = 30. Three thousand mg of royal jelly (RJ or a placebo in 100 ml liquid/day were ingested for 6 months. The primary outcomes were changes in anthropometric measurements and biochemical indexes from baseline to 6 months after intervention. Results Thirty subjects in the RJ group and 26 in the control group were included in the analysis of endpoints. In an adjusted mean change of the variables from the baseline, significant differences between the two groups could be found in red blood cell counts (+0.16x106 /μL for the RJ group vs. -0.01x106 /μL for the control group, P = 0.0134, hematocrit (+0.9% vs. -0.8%, P = 0.0251, log (fasting plasma glucose (+0.01 ± 0.01 log mg/dL vs. +0.05 ± 0.01 log mg/dL, P = 0.0297, log (insulinogenic index (+0.25 vs. -0.13, P = 0.0319, log dehydroepiandrosterone sulfate (DHEA-S (+0.08 log μg/dL vs. +0.20 log μg/dL, P = 0.0483, log testosterone (T (+0.12 ± 0.04 log ng/mL vs. -0.02 ± 0.05 log ng/mL, P = 0.0416, log T/DHEA-S ratio (+0.05 ± 0.05 vs. -0.23 ± 0.59, P = 0.0015, and in one of the SF-36 subscale scores, mental health (MH (+4 vs. -7, P = 0.0276. Conclusions Six-month ingestion of RJ in humans improved erythropoiesis, glucose tolerance and mental health. Acceleration of conversion from DHEA-S to T by RJ may have been observed among these favorable effects.

  14. Royal Order of 12 December 1975 setting up a National Energy Committee

    International Nuclear Information System (INIS)

    1978-01-01

    The National Energy Committee was set up by Royal Order of 12 December 1975. Its duties are to advise on the general objectives of energy policy and its implementation. It supervises execution of the policy and makes recommendations on matters within its competence. The Committee is chaired by the Minister for Economic Affairs and Energy and is composed of representatives of the Government, trade unions, undertakings, consumers, gas and electricity committees, oil and coal industries and a delegate of the Planning Department. This Order repeals the Order of 17 July 1957 creating an Energy Advisory Council. (NEA) [fr

  15. A short history of the Royal Odonto Chirurgical Society of Scotland.

    Science.gov (United States)

    Geissler, Paul R

    2014-01-01

    In the mid-19th Century, the practice of dentistry in Britain was unregulated and chaotic. Organised training was non-existent, and the public was unable to be assured of satisfactory, ethical treatment. A group of Scottish practitioners, led by John Smith, an Edinburgh surgeon, established the Odonto Chirurgical Society of Scotland in 1867 as an ethical dental society promoting education and regulation of the emerging profession. The Society has prospered over the years. It was granted the title "Royal" on the occasion of its centenary in 1967, and approaches its 150th year with confidence.

  16. The JASON reactor at the Royal Naval College: Silver Jubilee 6th November 1987

    International Nuclear Information System (INIS)

    Lakey, J.R.A.; Roust, C.B.

    1988-01-01

    The 10 kW Research and Training Reactor Jason has been used at the Royal Naval College for 25 years in support of the Naval Nuclear Submarine Propulsion Programme. The principal features of Jason, relevant to its training role are given, along with the specifications of Jason, instrumentation, maintenance and operational experience. The educational role of the reactor is described with respect to the Nuclear Reactor Course, Nuclear Advanced Course, and the Nuclear Radiation Protection Course. Future developments in operator training, advantages of the low power reactor, quality control of education and training, and research and development, are also discussed. (U.K.)

  17. Longevity extension of worker honey bees (Apis mellifera) by royal jelly: optimal dose and active ingredient

    OpenAIRE

    Yang, Wenchao; Tian, Yuanyuan; Han, Mingfeng; Miao, Xiaoqing

    2017-01-01

    In the Western honey bee, Apis mellifera, queens and workers have different longevity although they share the same genome. Queens consume royal jelly (RJ) as the main food throughout their life, including as adults, but workers only eat worker jelly when they are larvae less than 3 days old. In order to explore the effect of RJ and the components affecting longevity of worker honey bees, we first determined the optimal dose for prolonging longevity of workers as 4% RJ in 50% sucrose solution,...

  18. The Royal Naval Medical Services: delivering medical operational capability. the 'black art' of Medical Operational Planning.

    Science.gov (United States)

    Faye, M

    2013-01-01

    This article looks to dispel the mysteries of the 'black art' of Medical Operational Planning whilst giving an overview of activity within the Medical Operational Capability area of Medical Division (Med Div) within Navy Command Headquarters (NCHQ) during a period when the Royal Naval Medical Services (RNMS) have been preparing and reconfiguring medical capability for the future contingent battle spaces. The rolling exercise program has been used to illustrate the ongoing preparations taken by the Medical Operational Capability (Med Op Cap) and the Medical Force Elements to deliver medical capability in the littoral and maritime environments.

  19. Royal Decree-Law 1302/1986 of 28 June 1986 on environmental impact studies

    International Nuclear Information System (INIS)

    1986-01-01

    This Royal Decree-Law (No 1302/1986) of 28th June 1986 was published in the Official Gazette of 30th June 1986. The purpose of this Decree-Law is to provide for assessments of the environmental impact of certain projected installations and activities. The installations and activities requiring environmental impact studies are listed in the Annex to the Decree-Law and include nuclear power plants and other nuclear reactors (excluding those whose thermal power does not exceed 1 kW) as well as installations for the disposal and final storage of radioactive waste (NEA) [fr

  20. Un siècle de chimie à l'Académie royale des sciences

    OpenAIRE

    Coorebyter, Vincent de; Decaix, Véronique; Franckowiak, Rémi; Francobandiera, Daria; Ierna, Carlo; Jolly, Edouard; Joly, Bernard; Joly, Bernard; Joly, Bernard; Joly, Bernard; Lehman, Christine; Masselot, Nathanaël; Mazet, Edmond; Parmentier, Marc; Parmentier, Marc

    2012-01-01

    Le laboratoire alchimique, lieu privilégié de l’élaboration de la chimie ancienne, symbolisait à la fois le caractère privé, si ce n’est secret, de cette science et sa nécessaire articulation avec une pratique qui lui donnait son sens : il ne s’agissait pas seulement de trouver la pierre philosophale, mais aussi de fabriquer médicaments et substances chimiques répondant à des demandes sociales. L’introduction de la chimie parmi les « classes » de l’Académie royale des sciences va transformer ...

  1. Slim 198gold-grain implanter loaded with standard royal marsden 14-grain magazines

    International Nuclear Information System (INIS)

    Delclos, L.; Moore, E.B.

    1979-01-01

    We designed a slim gold-grain implanter with adaptable lengths to implant areas accessible only through long, narrow, examining instruments, such as a suspension laryngoscope. The implanter is loaded with the same 14-grain magazine designed for and supplied with the Royal Marsden gun. The simplicity of the loading mechanism with a minimum of moving parts makes the instrument practically trouble free. Although it is designed to be used along narrow examining instruments, it can also be used in any situation in which a permanent implant is required, for instance, prostatic cancer and pelvic recurrences in cancer of the uterine cervix previously treated by external and intracavitary irradiation

  2. Factors impacting on employee performance: A case study of the royal Swaziland police service

    Directory of Open Access Journals (Sweden)

    Nirmala Dorasamy

    2015-08-01

    Full Text Available The principal challenge for most organisations is to ensure that the performance of employees will result in the effectiveness and success of any organisation. The Royal Swaziland Police Service (RSPS, in order to differentiate itself from other organisations and ensure survival effectiveness and competitiveness, must render services of high quality. The key findings of the RSPS study suggest that the most positive factors of job satisfaction are receiving respect from the community and relations with colleagues, while the negative aspects are that salaries are not equal to effort put into the job and fear of victimization after voicing a personal opinion.

  3. RICH – A new AMS facility at the Royal Institute for Cultural Heritage, Brussels, Belgium

    Energy Technology Data Exchange (ETDEWEB)

    Boudin, Mathieu; Van Strydonck, Mark; Brande, Tess van den [Royal Institute for Cultural Heritage, Jubelpark 1, 1000 Brussels (Belgium); Synal, Hans-Arno; Wacker, Luckas [Laboratory of Ion Beam Physics, ETH Zurich, 8093 Zurich (Switzerland)

    2015-10-15

    Since 1989 the radiocarbon dating lab has their own graphitization system for {sup 14}C AMS dating but RICH (Royal Institute for Cultural Heritage) did not possess their own AMS and measurements were carried out in collaboration with other AMS facilities. In April 2013 the Micadas (Mini Carbon Dating System) AMS was installed at RICH in Brussels and after 1.5 year operation the high stability and performance of the Micadas can be demonstrated by repeated analyses of primary standard OXA II and secondary standards. Results of unknown samples measured on the RICH–Micadas and on other AMS systems are in good agreement.

  4. A tale of two hospitals: assessing cultural landscapes and compositions.

    Science.gov (United States)

    Braithwaite, Jeffrey; Westbrook, Mary T; Iedema, Rick; Mallock, Nadine A; Forsyth, Rowena; Zhang, Kai

    2005-03-01

    Clinical directorate service structures (CDs) have been widely implemented in acute settings in the belief that they will enhance efficiency and patient care by bringing teams together and involving clinicians in management. We argue that the achievement of such goals depends not only on changing its formalized structural arrangements but also the culture of the organisation concerned. We conducted comparative observational studies and questionnaire surveys of two large Australian teaching hospitals similar in size, role and CD structure. Martin's conceptualization of culture in terms of integration, differentiation and fragmentation was applied in the analysis of the data. The ethnographic work revealed that compared to Metropolitan Hospital, Royal Hospital was better supported and more favourably viewed by its staff across six categories identified in both settings: leadership, structure, communication, change, finance and human resource management. Royal staff were more optimistic about their organisation's ability to meet future challenges. The surveys revealed that both staff groups preferred CD to traditional structures and shared some favourable and critical views of them. However Royal staff were significantly more positive, reporting many more benefits from CDs e.g. improved working relations, greater accountability and efficiency, better cost management, more devolvement of management to clinicians and a hospital more strategically placed and patient focused. Metropolitan staff were more likely to claim that CDs failed to solve problems and created a range of others including disunity and poor working relationships. There was greater consensus of views among Royal staff and more fragmentation at Metropolitan where both intensely held and uncertain attitudes were more common. The outcomes of implementing CDs in these two similar organisations differed considerably indicating the need to address cultural issues when introducing structural change. Martin

  5. CPR and the RCP (1). Training of doctors in NHS hospitals.

    Science.gov (United States)

    Wheatly, S; Redmond, A D

    1993-10-01

    Six years after the Royal College of Physicians published its report, most hospitals in the UK with acute coronary beds fail to train or test their doctors adequately in the skills of cardiopulmonary resuscitation. Doctors want more training, and consultants try to give it, but there is a lack of funds for this basic yet critical task.

  6. The library of the Royal Society of Physicians in Budapest becomes today's Semmelweis Medical History Library.

    Science.gov (United States)

    Kaproncszay, Katalin; Magyar, László András; Putnam, Constance E

    2011-01-01

    The 170-year history of the library of the Royal Society of Medicine in Budapest illustrates both that political and cultural context matter and that "medical" libraries, if they survive, in due course become primarily "medical history" libraries. Two of the authors are on the staff of the Semmelweis Medical History Library; the third is a US scholar who makes frequent use of the library. Together, they avail themselves of archival and published materials-and personal experience with the collection-to establish the context that produced the original library, trace its evolution, and describe its present-day incarnation. A tale of transformation emerges that reflects how collections are likely to change. The authors present events and individuals in the life of the Royal Society's library and paint a picture of the value of today's Semmelweis Medical History Library. Unique treasures in the collection are described. The story told here is of how a particular nineteenth-century library became a twenty-first-century institution. The authors establish its peculiarly Hungarian context and potential value to librarians and historians from outside Hungary. The overall message is that general medical libraries everywhere are perforce likely to become medical historical libraries over time.

  7. Making Kew Observatory: the Royal Society, the British Association and the politics of early Victorian science.

    Science.gov (United States)

    Macdonald, Lee T

    2015-09-01

    Built in 1769 as a private observatory for King George III, Kew Observatory was taken over in 1842 by the British Association for the Advancement of Science (BAAS). It was then quickly transformed into what some claimed to be a 'physical observatory' of the sort proposed by John Herschel - an observatory that gathered data in a wide range of physical sciences, including geomagnetism and meteorology, rather than just astronomy. Yet this article argues that the institution which emerged in the 1840s was different in many ways from that envisaged by Herschel. It uses a chronological framework to show how, at every stage, the geophysicist and Royal Artillery officer Edward Sabine manipulated the project towards his own agenda: an independent observatory through which he could control the geomagnetic and meteorological research, including the ongoing 'Magnetic Crusade'. The political machinations surrounding Kew Observatory, within the Royal Society and the BAAS, may help to illuminate the complex politics of science in early Victorian Britain, particularly the role of 'scientific servicemen' such as Sabine. Both the diversity of activities at Kew and the complexity of the observatory's origins make its study important in the context of the growing field of the 'observatory sciences'.

  8. The 'royal disease'--haemophilia A or B? A haematological mystery is finally solved.

    Science.gov (United States)

    Lannoy, N; Hermans, C

    2010-11-01

      'History can change blood. And blood can change the course of history'. Haemophilia is an illustration of this, as this congenital hereditary coagulation disorder, passed through the majority of royal European families at the beginning of the 20th century by Queen Victoria of England and Empress of the Indies, had indisputable political consequences, which led to one of the most defining moments of contemporary history: the Bolshevik Revolution. Today, none of Queen Victoria's living descendents carry haemophilia. Because of this, the characterization of haemophilia (deficit of either factor VIII or XI) and the identification of the causal mutation are rendered impossible. In 1991, a tomb containing the remains of Czar Nicolas II's entire family was discovered. A second tomb was discovered in 2007, allowing Russian and American scientists to fill in this gap in medical history. Following a scientific approach combining current genetic experimentation tools and the development of biological information technology, researchers were able to identify each body, allowing them to obtain precious genetic material from the young Czar Alexis, who was stricken by the disease, which revealed a causal substitution in the splice acceptor site of exon 4 in the F9 gene. This mutation that is responsible for haemophilia B had traumatized European royal families throughout the 20th century! © 2010 Blackwell Publishing Ltd.

  9. [Tuberculosis in the Royal Norwegian Navy at the time of the Second World War].

    Science.gov (United States)

    Ongre, Aksel; Sommerfelt-Pettersen, Jan

    2008-12-18

    Tuberculosis became a great problem in the Royal Norwegian Navy during the first years of the Second World War (when it operated in allied services mainly from the UK); with the highest incidence (9.6 per 1 000) during the first half of 1943. Main reasons were insufficient medical examination of recruits, crowded living conditions on board (favoured the contagion) and the physical and psychological pressure during sea operations, which may have reduced the immune defence. Prophylactic measures in terms of tuberculin testing of all personnel, chest X-rays of the positives, vaccination of the negatives, environment investigation when disease was discovered, and isolation of those infected, gave control from the second half of 1943 and onwards. The article also mentions treatment, repatriation and the incidence of tuberculosis in the Norwegian Navy before and after the war as well as in the Royal Canadian Naval Services (where the incidence was low) during the war. Today, the tuberculosis situation in Norway is so favourable that routine chest X-ray of the recruits is no longer performed in the armed forces.

  10. Molecular genetic analysis on the remains of the Dark Countess: Revisiting the French Royal family.

    Science.gov (United States)

    Parson, Walther; Berger, Cordula; Sänger, Timo; Lutz-Bonengel, Sabine

    2015-11-01

    The "Dark Counts" were a mysterious couple that appeared in the Thuringian village Eishausen in 1807. After living in self imposed solitude for 30 years the woman died and was buried under the name Sophia Botta. Her companion, who presented himself as Vavel de Versay, died in 1845 and was later identified as Leonardus Cornelius van der Valck, secretary of the Dutch embassy in Paris. Their lifestyle led to speculations that she was the true princess Marie Thérèse Charlotte of France, daughter of Louis XVI and Marie Antoinette. According to these speculations she was substituted by another young woman on a voyage from Paris to Vienna. Molecular genetic analyses were set out to test the remains attributed to the Dark Countess. Mitochondrial DNA testing brought concordant results determined in two forensic laboratories (Innsbruck, Austria and Freiburg, Germany) on parallel samples of the remains. The results were in exclusion to both, the mitochondrial lineage earlier reported for the French Royal family and the mitochondrial haplotype observed in a living descendant of the Royal family. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  11. Introducing Union Representation and Its Complexities – A Case Study of the Royal Thai Civil Service

    Directory of Open Access Journals (Sweden)

    Maarten Pontier

    2016-01-01

    Full Text Available This paper deals with the result of the recognition under the ILO Conventions 87 and 98 of the freedom of association and subsequent introduction of union representation in the Royal Thai civil service. As a consequence, the Royal Thai Government has changed the Constitution to allow for union representation in its civil service. A decree has been drafted and focus groups have been interviewed to establish the views of a cross-section of civil servants on their expectations and desires in being allowed to form and join a union. The paper discusses the approach taken to union representation in terms of collective bargaining versus joint consultation and centralization versus decentralization and the discourse that has surfaced as a result of the interviews between the policy makers and civil servants, particularly with regard to its context of a high power distance culture. The analysis provides the best practice and effective approach to the introduction of union representation within the Thai Civil Service.

  12. Surgical capacity building in Timor-Leste: a review of the first 15 years of the Royal Australasian College of Surgeons-led Australian Aid programme.

    Science.gov (United States)

    Guest, Glenn D; Scott, David F; Xavier, Joao P; Martins, Nelson; Vreede, Eric; Chennal, Antony; Moss, Daliah; Watters, David A

    2017-06-01

    Timor-Leste suffered a destructive withdrawal by the Indonesian military in 1999, leaving only 20 Timorese-based doctors and no practising specialists for a population of 700 000 that has now grown to 1.2 million. This article assesses the outcomes and impact of Royal Australasian College of Surgeons (RACS) specialist medical support from 2001 to 2015. Three programmes were designed collaboratively with the Timor-Leste Ministry of Health and Australian Aid. The RACS team began to provide 24/7 resident surgical and anaesthesia services in the capital, Dili, from July 2001. The arrival of the Chinese and Cuban Medical Teams provided a medical workforce, and the Cubans initiated undergraduate medical training for about 1000 nationals both in Cuba and in Timor-Leste, whilst RACS focused on specialist medical training. Australian Aid provided AUD$20 million through three continuous programmes over 15 years. In the first 10 years over 10 000 operations were performed. Initially only 10% of operations were done by trainees but this reached 77% by 2010. Twenty-one nurse anaesthetists were trained in-country, sufficient to cover the needs of each hospital. Seven Timorese doctors gained specialist qualifications (five surgery, one ophthalmology and one anaesthesia) from regional medical schools in Papua New Guinea, Fiji, Indonesia and Malaysia. They introduced local specialist and family medicine diploma programmes for the Cuban graduates. Timor-Leste has developed increasing levels of surgical and anaesthetic self-sufficiency through multi-level collaboration between the Ministry of Health, Universidade Nacional de Timor Lorosa'e, and sustained, consistent support from external donors including Australian Aid, Cuba and RACS. © 2016 Royal Australasian College of Surgeons.

  13. The 'unnecessary' use of emergency departments by older people: findings from hospital data, hospital staff and older people.

    Science.gov (United States)

    Faulkner, Debbie; Law, Julia

    2015-11-01

    Increasing demands are being placed on emergency departments in Australia and there is a view that older Australians are more likely than other age groups to attend for non-urgent conditions. The objective of this paper is to compare and contrast administrative data with the views of hospital staff and older people with regard to their presentation at two emergency departments in metropolitan Adelaide and how this aligns with the Australian Institute of Health and Welfare definition of 'potentially avoidable general practitioner-type presentations'. The study used three sources of data from two emergency departments: hospital data for the financial year 2010-11 for patients aged 65 years and over and identified as triage category four or five; three focus groups with medical, nursing and allied staff from these two hospitals; and interviews with 58 older people who presented at the two emergency departments over a two-week period. The hospital administrative data provided a very limited insight into why older people attended the emergency department, other than the medical diagnosis. Professional staff identified individual determinants, societal determinants and the health services system as explanations. Older people attended the emergency department for a range of reasons that may not necessarily reflect the opinions of health professionals. For many older people the emergency department was an appropriate place to attend considering their condition, though some presentations could be circumvented with appropriate and increased services in the community. However, as many older people suffer comorbidities, careful consideration needs to be given as to the best possible practices to achieve this.

  14. The deleterious effects of arteriovenous fistula-creation on the cardiovascular system: a longitudinal magnetic resonance imaging study

    Directory of Open Access Journals (Sweden)

    Dundon BK

    2014-09-01

    Full Text Available Benjamin K Dundon,1–3 Kim Torpey,3 Adam J Nelson,1 Dennis TL Wong,1,2 Rae F Duncan,1 Ian T Meredith,2 Randall J Faull,1,3 Stephen G Worthley,1,4 Matthew I Worthley1,4 1Cardiology Department, Royal Adelaide Hospital, Central Adelaide Local Health Network, Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia; 2Monash Cardiovascular Research Centre, MonashHEART, Monash Health, Melbourne, Vic, Australia; 3Central Northern Renal and Transplantation Service, Royal Adelaide Hospital, Central Adelaide Local Health Network, Adelaide, SA, Australia; 4South Australian Health and Medical Research Institute, Adelaide, SA, Australia Aim: Arteriovenous fistula-formation remains critical for the provision of hemodialysis in end-stage renal failure patients. Its creation results in a significant increase in cardiac output, with resultant alterations in cardiac stroke volume, systemic blood flow, and vascular resistance. The impact of fistula-formation on cardiac and vascular structure and function has not yet been evaluated via "gold standard" imaging techniques in the modern era of end-stage renal failure care. Methods: A total of 24 patients with stage 5 chronic kidney disease undergoing fistula-creation were studied in a single-arm pilot study. Cardiovascular magnetic resonance imaging was undertaken at baseline, and prior to and 6 months following fistula-creation. This gold standard imaging modality was used to evaluate, via standard brachial flow-mediated techniques, cardiac structure and function, aortic distensibility, and endothelial function. Results: At follow up, left ventricular ejection fraction remained unchanged, while mean cardiac output increased by 25.0% (P<0.0001. Significant increases in left and right ventricular end-systolic volumes (21% [P=0.014] and 18% [P<0.01], left and right atrial area (11% [P<0.01] and 9% [P<0.01], and left ventricular mass were observed (12.7% increase (P<0.01. Endothelial

  15. Ethylene inhibitor aminoethoxyvinilglycine on glomerella leaf spot in apple cultivar 'Royal Gala' Inibidor de etileno aminoetoxivinilglicina sobre a mancha foliar de 'Glomerella' na cultivar de macieira 'Royal Gala'

    Directory of Open Access Journals (Sweden)

    Amauri Bogo

    2011-06-01

    Full Text Available Aqueous solution of Aminoethoxyvinylglycine (AVG has been commercialized in Brazil as ReTainTM C, 15% mainly as a potent inhibitor of ethylene biosynthesis by prevention of pre-harvest abscission and ripening of apple fruits. The effect of the product was evaluated during the 2007-08 and 2008-09 crop seasons in edafoclimatic conditions of Santa Catarina upland. Plants of 'Royal Gala' cultivar were sprayed with ReTainTM C, four weeks before the first commercial harvest at doses of 0; 62,5; 125, and 250mg a.i L-1. The incidence and severity were quantified weekly in 100 leaves distributed in four branches with 12 replications and assessed the area under the incidence -I and severity -S disease progress curve (AUIDPC and AUSDPC of Glomerella leaf spot (GLS. The AUIDPC and AUSDPC were significantly higher after AVG application and although there was no significant difference between 125 and 250mg a.i L-1 doses in both 2007-08 and 2008-09 crop seasons. In general, the symptoms of GLS (e.g. chlorosis, necrosis increased between the fourth and eighth week after application.Solução aquosa de Aminoetoxivinilglicina (AVG tem sido comercializada no Brasil como ReTainTM C, 15%, principalmente como um potente inibidor da biossíntese do etileno na prevenção da abscisão e maturação de frutos em macieira. O efeito do produto foi avaliado durante as safras 2007-08 e 2008-09 nas condições edafo-climáticas do planalto Catarinense. Plantas de maçãs 'Royal Gala' foram pulverizadas com o ReTainTM C, quatro semanas antes da primeira colheita comercial, nas concentrações de 0;62,5; 125 e 250mg i.a L-1. A incidência e a severidade foram quantificadas semanalmente em 100 folhas, distribuídas em quatro ramos por plantas, com 12 repetições e calculado a área abaixo da curva do progresso da incidência -I e severidade -S da doença (AACPID e AACPSD. A AACPID e AACPSD foram significativamente maiores após a aplicação do AVG e não houve diferen

  16. Royal College surgical objectives of urologic training: A survey of faculty members from Canadian training programs

    Science.gov (United States)

    Zakaria, Ahmed S.; Haddad, Richard; Dragomir, Alice; Kassouf, Wassim; Andonian, Sero; Aprikian, Armen G.

    2014-01-01

    Introduction: According to the Royal College objectives of training in urology, urologic surgical procedures are divided as category A, B and C. We wanted to determine the level of proficiency required and achieved by urology training faculty for Royal College accreditation. Methods: We conducted a survey that was sent electronically to all Canadian urology training faculty. Questions focused on demographics (i.e., years of practice, geographic location, subspecialty, access to robotic surgery), operating room contact with residents, opinion on the level of proficiency required from a list of 54 surgical procedures, and whether their most recent graduates attained category A proficiency in these procedures. Results: The response rate was 43.7% (95/217). Among respondents, 92.6% were full timers, 21.1% practiced urology for less than 5 years and 3.2% for more than 30 years. Responses from Quebec and Ontario formed 69.4% (34.7% each). Of the respondents, 37.9% were uro-oncologists and 75.7% reported having access to robotic surgery. Sixty percent of faculty members operate with R5 residents between 2 to 5 days per month. When respondents were asked which categories should be listed as category A, only 8 procedures received 100% agreement. Also, results varied significantly when analyzed by sub-specialty. For example, almost 50% or more of uro-oncologists believed that radical cystectomy, anterior pelvic exenteration and extended pelvic lymphadenectomy should not be category A. The following procedures had significant disagreement suggesting the need for re-classification: glanular hypospadias repair, boari flap, entero-vesical and vesicovaginal fistulae repair. Overall, more than 80% of faculty reported that their recent graduating residents had achieved category A proficiency, in a subset of procedures. However, more than 50% of all faculty either disagreed or were ambivalent that all of their graduating residents were Category A proficient in several procedures

  17. Royal Order of 24 May 1977 amending the Royal Order of 28 February 1963 on General Regulations for Protection of the Population and Workers against the Hazards of Ionizing Radiations

    International Nuclear Information System (INIS)

    1977-01-01

    This Royal Order amends the Royal Order of 28 February 1963, as revised, embodying the General Regulations for the Protection of the Population and Workers against the Hazards of Ionizing Radiations. The amendment refers in particular to the conditions for the direct supply by manufacturers or importers of unsealed radioactive substances, radioisotopes or preparations containing them, to duly authorized physicians, veterinary surgeons and chemists. It also refers to the conditions of use of devices and substances emitting ionizing radiations, as well as to the licensing conditions for holders of isotopes and the qualifications of users. (NEA) [fr

  18. The Royal Society, natural history and the peoples of the 'New World(s)', 1660-1800.

    Science.gov (United States)

    Gascoigne, John

    2009-12-01

    This paper focuses on the response of the Royal Society to the increasing contact with parts of the globe beyond Europe. Such contact was in accord with the programme of Baconian natural history that the early Royal Society espoused, but it also raised basic questions about the extent and nature of the pursuit of natural history. In particular, the paper is concerned with the attention paid to one particular branch of natural history, the study of other peoples and their customs. Such scrutiny of other peoples in distant lands raised basic questions about what methods natural history should employ and the extent to which it could serve as a foundation for more general and theoretical claims. By taking a wide sweep from the beginnings of the Royal Society until the end of the eighteenth century it is hoped light will be shed on the changing understanding of natural history over this period.

  19. From the Activity of ‘Prince Carol’Royal Cultural Foundation 1922-1948 Archive Documents (II

    Directory of Open Access Journals (Sweden)

    Laura Rodica Hîmpă

    2014-01-01

    Full Text Available This research aims to emphasize the activity of the ‘Prince Carol’ Royal Cultural Foundation created in 1921 in order to lead to the emancipation of villages in particular and of the Romanian culture in a more general perspective. Overall, we may say that the period between the two world wars was marked, also due to the help of the Royal Cultural Foundation, by substantial progress in various fields of education, science and culture in general, and thus contributed to changing Romania into a state with a high level of culture and to creating an image and a prestige of the country that commanded worldwide respect. The research was done on the basis of the documents studied at the Service of the Central National Historical Archives (SANIC, the Stock of the ‘Prince Carol’ Royal Cultural Foundation and at the Library of the Romanian Academy.

  20. Designing new collaborative learning spaces in clinical environments: experiences from a children's hospital in Australia.

    Science.gov (United States)

    Bines, Julie E; Jamieson, Peter

    2013-09-01

    Hospitals are complex places that provide a rich learning environment for students, staff, patients and their families, professional groups and the community. The "new" Royal Children's Hospital opened in late 2011. Its mission is focused on improving health and well-being of children and adolescents through leadership in healthcare, research and education. Addressing the need to create "responsive learning environments" aligned with the shift to student-centred pedagogy, two distinct learning environments were developed within the new Royal Children's Hospital; (i) a dedicated education precinct providing a suite of physical environments to promote a more active, collaborative and social learning experience for education and training programs conducted on the Royal Children's Hospital campus and (ii) a suite of learning spaces embedded within clinical areas so that learning becomes an integral part of the daily activities of this busy Hospital environment. The aim of this article is to present the overarching educational principles that lead the design of these learning spaces and describe the opportunities and obstacles encountered in the development of collaborative learning spaces within a large hospital development.

  1. Sperm abnormality toxicity due to cyclosporine A and the ameliorative effect of royal jelly in male rats

    Directory of Open Access Journals (Sweden)

    Azza M. Gawish

    2016-08-01

    Full Text Available The immunosuppressive drug, utilized widely in Egypt, cyclosporine A was studied to evaluate its toxicity in male rats. Animals were divided into a control (untreated, 3 groups treated intraperitoneally with 20, 40 and 60 m/kg cyclosporine A for 5, 10 and 15 days, respectively and 3 groups treated intraperitoneally with 20, 40 and 60 mg/kg of cyclosporine A plus 100 mg/kg royal jelly administrated orally. Toxicity evaluation was carried out using two main endpoints: reproductive study (sperm morphology and count abnormalities and biochemical changes in liver and testis (DNA amounts. The aim of this work is to study the protective role of royal jelly against sperm abnormalities in shape and count, and changes in DNA contents in liver and testis tissue induced in rats when treated by cyclosporine A with different doses (20–40–60 mg/kg/day for 5, 10, and 15 days in male rats and how the royal jelly can repair this changes. Our results showed that sperm abnormalities induced by cyclosporine A included deviation from normal shape in head and tail. Abnormal heads contained amorphous head and banana-shaped head, whereas the abnormal tails included divided and coiled tails. It also induced an insignificant effect on the total sperm counts after 5 days of injection with the drug combined with royal jelly. DNA contents were determined in rat liver and testis cells to illustrate the mutagenic effect of cyclosporine A and how the royal jelly can modulate this effect. From these results we concluded that cyclosporine A toxicity was dose and time dependent and should be administrated under special precautions and medical supervision. Using of royal jelly in combination with cyclosporine A drug decreased its toxic effect, so it's considered as protector.

  2. Deposition and cycling of sulfur controls mercury accumulation in Isle Royale fish

    Energy Technology Data Exchange (ETDEWEB)

    Paul E. Drevnick; Donald E. Canfield; Patrick R. Gorski (and others) [Miami University, Oxford, OH (United States). Department of Zoology

    2007-11-01

    Mercury contamination of fish is a global problem. Consumption of contaminated fish is the primary route of methylmercury exposure in humans and is detrimental to health. Newly mandated reductions in anthropogenic mercury emissions aim to reduce atmospheric mercury deposition and thus mercury concentrations in fish. However, factors other than mercury deposition are important for mercury bioaccumulation in fish. In the lakes of Isle Royale, U.S.A., reduced rates of sulfate deposition since the Clean Air Act of 1970 have caused mercury concentrations in fish to decline to levels that are safe for human consumption, even without a discernible decrease in mercury deposition. Therefore, reductions in anthropogenic sulfur emissions may provide a synergistic solution to the mercury problem in sulfate-limited freshwaters. 71 refs., 3 figs., 1 tab.

  3. The Phenotypic Effects of Royal Jelly on Wild-Type D. melanogaster Are Strain-Specific.

    Directory of Open Access Journals (Sweden)

    Stefanie L Morgan

    Full Text Available The role for royal jelly (RJ in promoting caste differentiation of honeybee larvae into queens rather than workers is well characterized. A recent study demonstrated that this poorly understood complex nutrition drives strikingly similar phenotypic effects in Drosophila melanogaster, such as increased body size and reduced developmental time, making possible the use of D. melanogaster as a model system for the genetic analysis of the cellular mechanisms underlying RJ and caste differentiation. We demonstrate here that RJ increases the body size of some wild-type strains of D. melanogaster but not others, and report significant delays in developmental time in all flies reared on RJ. These findings suggest that cryptic genetic variation may be a factor in the D. melanogaster response to RJ, and should be considered when attempting to elucidate response mechanisms to environmental changes in non-honeybee species.

  4. The report of the Royal Commission into British nuclear tests in Australia

    International Nuclear Information System (INIS)

    Anon.

    1985-01-01

    The conclusions and recommendations of the Royal commission into British nuclear tests conducted in Australia between 1952 and 1963 are presented. The recommendations include that action should be commenced immediately to effect a clean-up of Maralinga and Emu so that they are fit for unrestricted habitation by the traditional Aboriginal owners as soon as practicable; all costs of any future clean-ups at Maralinga, Emu and the Monte Bello Islands should be borne by the United Kingdom Government; a Maralinga Commission should be established to determine the clean-up criteria, oversee the clean-up and co-ordinate all future Range management; the Australian government should make compensation to those persons and descendants of those persons who have a traditional interest in sites at the former Maralinga Prohibited Area for loss of use and enjoyment of their lands since the beginning, and as a result of the atomic tests program

  5. MANAGEMENT ART - The Royal Danish Opera's Artistic Director Kasper Bech Holten as case

    DEFF Research Database (Denmark)

    Nørreklit, Hanne

    successful Artistic Director of the Royal Danish Opera, Kasper Bech Holten. The analysis shows that conventional management models primarily use the symbolic forms of science and myth, while Kasper integrates the symbolic forms of art and science. In what Kasper has to say on management, features...... and structures for a new management discourse practice emerge which is more suited to postmodern society than more conventional management models.......This article investigates whether it would be expedient for our management models to be inspired by art as a form of consciousness. With this in mind, the article analyses the symbolic forms embedded in the management discourse practice of art in the way that the concept is unfolded by the highly...

  6. Compromises in orchestra pit design: A ten-year trench war in The Royal Theatre, Copenhagen

    DEFF Research Database (Denmark)

    Gade, Anders Christian; Mortensen, Bo

    1998-01-01

    of opera finally opened the way for a new renovation of the pit, which solved most of the problems. The paper describes the many lessons learned during the ten-year period in which the authors were involved with the case as acoustic consultants. Questions of how pit configuration influences mutual hearing......The ``old stage'' of The Royal Theatre in Copenhagen-a classical horseshoe theatre with an almost flat audience floor and four balcony levels—is the primary opera and ballet theatre in Denmark. In the early 1980s the orchestra pit was enlarged and its size made flexible. However, in the following...... years this new flexibility caused a formal battle between the orchestra, the singers, and management, because each group had different interests as to how the pit should be configured for each new production. In the 1990s, increased concern about the musicians' hearing and the increase in the popularity...

  7. The last Viking King: a royal maternity case solved by ancient DNA analysis

    DEFF Research Database (Denmark)

    Dissing, Jørgen; Binladen, Jonas; Hansen, Anders

    2006-01-01

    Estridsen to haplogroup H; Estrid's sequence differed from that of Sven at two positions in HVR-1, 16093T-->C and 16304T-->C, indicating that she belongs to subgroup H5a. Given the maternal inheritance of mtDNA, offspring will have the same mtDNA sequence as their mother with the exception of rare cases...... doubts among historians whether the woman entombed was indeed Estrid. To shed light on this problem, we have extracted and analysed mitochondrial DNA (mtDNA) from pulp of teeth from each of the two royals. Four overlapping DNA-fragments covering about 400bp of hypervariable region 1 (HVR-1) of the D...

  8. Royal Military College of Canada SLOWPOKE-2 facility. Integrated regulating and instrumentation system (SIRCIS) upgrade project

    International Nuclear Information System (INIS)

    Corcoran, W.P.; Nielsen, K.S.; Kelly, D.G.; Weir, R.D.

    2013-01-01

    The SLOWPOKE-2 Facility at the Royal Military College of Canada has operated the only digitally controlled SLOWPOKE reactor since 2001 (Version 1.0). The present work describes ongoing project development to provide a robust digital reactor control system that is consistent with Aging Management as summarized in the Facility's Life Cycle Management and Maintenance Plan. The project has transitioned from a post-graduate research activity to a comprehensively managed project supported by a team of RMCC professional and technical staff who have delivered an update of the V1.1 system software and hardware implementation that is consistent with best Canadian nuclear industry practice. The challenges associated with the implementation of Version 2.0 in February 2012, the lessons learned from this implementation, and the applications of these lessons to a redesign and rewrite of the RMCC SLOWPOKE-2 digital instrumentation and regulating system (Version 3) are discussed. (author)

  9. Comparative Study on Quality Parameters of Royal Jelly, Apilarnil and Queen Bee Larvae Triturate

    Directory of Open Access Journals (Sweden)

    Rodica MARGAOAN

    2017-05-01

    Full Text Available Given their beneficial effects in terms of health, the natural products, especially beehive products, have drawn the attention of consumers since long time ago. In order to guarantee the quality of these products on the market, their chemical composition needs to be analyzed. Thus, this current research had as objective the establishment of quality parameters for beehive brood food derived products: apilarnil and queen bee larvae triturate. These two products were compared with royal jelly which is the basis of brood food in the first 3 days of larval stage. The carbohydrates were determined by HPLC-IR and allowed the identification of seven carbohydrate compounds, predominantly glucose, fructose and sucrose. The lipid profile was analyzed by the Soxhlet method. The total protein content was determined by the Kjeldahl method. Free amino acids were analyzed by LC-MS. A total of 31 amino acids were identified of which nine are essential amino acids for humans.Â

  10. Key Enablers of Effective Implementation of TQM in Royal Jet Airways

    Directory of Open Access Journals (Sweden)

    Moza Tahnoon Al Nahyan

    2017-01-01

    Full Text Available Total quality management (TQM is a unified management approach that concentrates on the consecutive improvement of processes, products, and methods to surpass client expectations. This paper aims to highlight the advantages of implementing TQM in the airline industry by examining the key enablers of TQM. This study was based on a research model including six factors that were found to have a profound influence in implementing TQM. The data needed for the study was collected with the aid of questionnaires and secondary sources. The study discovered that procedures, policies, and a culture of knowledge transfer were the most significant enablers of successful TQM initiatives in Royal Jet Airways. In order to effectively implement TQM, the study suggests that management should offer appropriate recognition and rewards to employees. This will motivate them to adopt and practice TQM initiatives. Apart from that, management should also arrange seminars or workshops to accustom the employees to the basic procedures and objectives of effective TQM.

  11. The discovery of microorganisms by Robert Hooke and Antoni Van Leeuwenhoek, fellows of the Royal Society.

    Science.gov (United States)

    Gest, Howard

    2004-05-01

    The existence of microscopic organisms was discovered during the period 1665-83 by two Fellows of The Royal Society, Robert Hooke and Antoni van Leeuwenhoek. In Micrographia (1665), Hooke presented the first published depiction of a microganism, the microfungus Mucor. Later, Leeuwenhoek observed and described microscopic protozoa and bacteria. These important revelations were made possible by the ingenuity of Hooke and Leeuwenhoek in fabricating and using simple microscopes that magnified objects from about 25-fold to 250-fold. After a lapse of more than 150 years, microscopy became the backbone of our understanding of the roles of microbes in the causation of infectious diseases and the recycling of chemical elements in the biosphere.

  12. Seventeenth-century 'treasure' found in Royal Society archives: the Ludus helmontii and the stone disease.

    Science.gov (United States)

    Alfonso-Goldfarb, Ana Maria; Ferraz, Márcia Helena Mendes; Rattansi, Piyo M

    2014-09-20

    Our archival researches at the Royal Society reveal that a small envelope attached to a 1675 letter from an Antwerp apothecary, A. Boutens, contained a sample of the 'Ludus' prepared as a remedy for the 'stone disease' then sweeping through Europe, which was first announced in J. B. van Helmont's De lithiasi (1644). After examining the fascination with the medical use of the Ludus (which required the 'alkahest' for its preparation) and the tenacious efforts to procure it, we trace the fortunae of two other ludi in England, brought to and offered by Francis Mercurius van Helmont during his English sojourn. Both eventually found their way to the geologist John Woodward, one of them through Sir Isaac Newton. Finally we show how the allure of the Ludus helmontii vanished, with transformations in mineral analysis and reclassifications from Woodward to John Hill.

  13. Radiographic facilities and their utilization at the Royal Military College of Science

    International Nuclear Information System (INIS)

    Carter, A.C.; Wilson, C.G.

    1976-01-01

    Non-destructive testing is playing an ever-increasing role in the design and production of weapons and material for the Ministry of Defence and the modern Army staff officer or officer in a technical corps must have the scientific and technological background to appreciate this importance. Some Army staff officers will be required to discuss the design of projects with civilian engineers and research staff and give judgement decisions involving NDT tests of weapons and equipment during and after manufacture and also after field use, etc. Radiography plays a key role in this work. The range of equipment utilised in x and γ-radiography, and experiments using these, described here are used at the Royal Military College of Science, UK for the education of such personnel. (U.K.)

  14. Malignant mast cell tumor of the thymus in an Royal College of Surgeons (RCS) rat.

    Science.gov (United States)

    Terayama, Yui; Matsuura, Tetsuro; Ozaki, Kiyokazu

    2017-01-01

    A 152-week-old male Royal College of Surgeons (RCS) rat kept as a non-treated animal in a long-term animal study presented with a soft mass in the anterior mediastinum, which adhered to the pleura of the lung. Histopathologically, the mass mainly consisted of round to short spindle-shaped tumor cells that had infiltrated through the hyperplastic thymic tissue. The tumor cells were arranged in loose to dense sheets. Nuclei were moderate in size and round to spindle-shaped, with small nucleoli. Almost all tumor cells exhibited abundant eosinophilic cytoplasm, including eosinophilic granules of a range of sizes. The granules of tumor cells exhibited metachromasia with toluidine blue stain and were positive for c-kit and mast cell protease II. These findings indicate that the tumor described here represents a rare case of spontaneous malignant mast cell tumor with thymic epithelial hyperplasia.

  15. AN AUTOPSIC ART: DRAWINGS OF 'DR GRANVILLE'S MUMMY' IN THE ROYAL SOCIETY ARCHIVES.

    Science.gov (United States)

    Riggs, Christina

    2016-06-20

    In 1821 Augustus Bozzi Granville FRS unwrapped and dissected an ancient Egyptian mummy, presenting the results of his examination to the Royal Society in 1825. He commissioned artist Henry Perry to draw the process in stages; these drawings were subsequently engraved by James Basire for publication in Philosophical Transactions. This article presents the original drawings for the first time, allowing comparison with their engravings. Taken together with Granville's accounts of the unwrapping of the mummy, the drawings demonstrate the significant role of illustration and other visual practices in anatomical argumentation in the early nineteenth century, as well as the prestige that commissioned illustrations lent to the performance and dissemination of scientific expertise. Moreover, the drawings include one of the key visual tropes of race science--a skull in left-facing profile, mapped with a facial angle--and thus indicate the early incorporation of Egyptian mummies into typologies of race.

  16. An autopsic art: drawings of ‘Dr Granville's mummy’ in the Royal Society archives

    Science.gov (United States)

    Riggs, Christina

    2016-01-01

    In 1821 Augustus Bozzi Granville FRS unwrapped and dissected an ancient Egyptian mummy, presenting the results of his examination to the Royal Society in 1825. He commissioned artist Henry Perry to draw the process in stages; these drawings were subsequently engraved by James Basire for publication in Philosophical Transactions. This article presents the original drawings for the first time, allowing comparison with their engravings. Taken together with Granville's accounts of the unwrapping of the mummy, the drawings demonstrate the significant role of illustration and other visual practices in anatomical argumentation in the early nineteenth century, as well as the prestige that commissioned illustrations lent to the performance and dissemination of scientific expertise. Moreover, the drawings include one of the key visual tropes of race science—a skull in left-facing profile, mapped with a facial angle—and thus indicate the early incorporation of Egyptian mummies into typologies of race. PMID:27386713

  17. The logic of scientific unity? Medawar, the Royal Society and the Rothschild controversy 1971–72

    Science.gov (United States)

    Calver, Neil; Parker, Miles

    2016-01-01

    In 1971 Lord (Victor) Rothschild published his report for the government, The organisation and management of government R&D, and Sir Peter Medawar launched a campaign for the election of Sir Karl Popper to Fellowship of the Royal Society. We explore these two developments in the contexts of the then current views of the role and purpose of science, and their underpinning philosophy. Although the political battle was won by Rothschild, resulting in major changes to the funding and management of applied R&D, we argue that, despite this, Medawar's campaign for Popper provided an embattled science community with a philosophical basis for defending pure research and the unity of basic and applied science. PMID:27017681

  18. THE LOGIC OF SCIENTIFIC UNITY? MEDAWAR, THE ROYAL SOCIETY AND THE ROTHSCHILD CONTROVERSY 1971-72.

    Science.gov (United States)

    Calver, Neil; Parker, Miles

    2016-03-20

    In 1971 Lord (Victor) Rothschild published his report for the government, The organisation and management of government R&D, and Sir Peter Medawar launched a campaign for the election of Sir Karl Popper to Fellowship of the Royal Society. We explore these two developments in the contexts of the then current views of the role and purpose of science, and their underpinning philosophy. Although the political battle was won by Rothschild, resulting in major changes to the funding and management of applied R&D, we argue that, despite this, Medawar's campaign for Popper provided an embattled science community with a philosophical basis for defending pure research and the unity of basic and applied science.

  19. Adaptogenic potential of royal jelly in liver of rats exposed to chronic stress.

    Directory of Open Access Journals (Sweden)

    Douglas Carvalho Caixeta

    Full Text Available Restraint and cold stress increase both corticosterone and glycemia, which lead to oxidative damages in hepatic tissue. This study assessed the effect of royal jelly (RJ supplementation on the corticosterone level, glycemia, plasma enzymes and hepatic antioxidant system in restraint and cold stressed rats. Wistar rats were allocated into no-stress, stress, no-stress supplemented with RJ and stress supplemented with RJ groups. Initially, RJ (200mg/Kg was administered for fourteen days and stressed groups were submitted to chronic stress from the seventh day. The results showed that RJ supplementation decreases corticosterone levels and improves glycemia control after stress induction. RJ supplementation also decreased the body weight, AST, ALP and GGT. Moreover, RJ improved total antioxidant capacity, SOD activity and reduced GSH, GR and lipoperoxidation in the liver. Thus, RJ supplementation reestablished the corticosterone levels and the hepatic antioxidant system in stressed rats, indicating an adaptogenic and hepatoprotective potential of RJ.

  20. Radiofrequency radiation: safe working practices in the Royal Australian Air Force

    International Nuclear Information System (INIS)

    Joyner, K.H.; Stone, K.R.

    1988-01-01

    The Royal Australian Air Force (RAAF) has long recognised the value of its work force and the need to preserve their health and wellbeing to achieve operational objectives. The Directorate of Air Force Safety (DAFS) is required by the Chief of the Air Staff to take all measures possible to prevent accidents and incidents in the RAAF, under the provisions of the Defence Instruction, 'Air Force Safety and Occupational Health Policy'. Consequently, the RAAF has exercised a pragmatic approach to radiofrequency radiation (RFR) and has always adopted and implemented strict exposure standards. DAFS receives technical advice on RFR from the Directorate of Telecommunications Engineering (DTELENG) and on occupational health from the Directorate General of Air Force Health Services (DGAFHS)

  1. The Royal Philanthropic Expedition of the Vaccine: a landmark in the history of public health.

    Science.gov (United States)

    Soto-Pérez-de-Celis, E

    2008-11-01

    In 1979, smallpox officially became the first disease ever to be eradicated by mankind. The global efforts to defeat this dreadful pandemic, however, started almost two centuries before. One of the most important, and sometimes forgotten, events in the fight against smallpox was the Royal Philanthropic Expedition of the Vaccine, commissioned by Charles IV of Spain to physicians Francisco Xavier Balmis y Berenguer and Jose Salvany in 1804. The aim of this expedition was to take the smallpox vaccine, discovered by Jenner, to Spain's territories in the Americas and in the Far East. After several years of vaccination in modern day Puerto Rico, Cuba, Venezuela, Ecuador, Peru, Bolivia, Chile, Mexico and the Philippines, the expedition returned to Europe. To this day, the Balmis and Salvany expedition remains a great example of international cooperation, and a landmark in the history of public health.

  2. Energy - the changing climate. Summary of the Royal Commission on Environmental Pollution's report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    In August 1997 the Royal Commission announced that it intended to review energy prospects for the 21st century and their environmental implications. In September 1998 it said its main focus would be the implications of considerably reducing the use of fossil fuels as an energy source in the UK by 2050, or even phasing them out completely. Evidence was invited on 23 specific issues. This document begins with a brief summary of the twenty-second report, Energy - The Changing Climate. This is followed by a short description of four UK energy scenarios for 2050. The key recommendations are given followed by a list of all the recommendations on which the government could act now. 8 figs., 15 photos.

  3. Concussion knowledge among Sport Chiropractic Fellows from the Royal College of Chiropractic Sports Sciences (Canada).

    Science.gov (United States)

    Kazemi, Mohsen; Bogumil, Mary Emma; Vora, Khushboo

    2017-12-01

    The objective of this study was to investigate the degree of knowledge that sports chiropractors have in regard to concussion diagnosis and management. A concussion knowledge survey was administered to Sport Chiropractic Fellows of the Royal College of Chiropractic Sports Sciences - Canada (RCCSS(C)) (n=44) via SurveyMonkey.com. Sports chiropractors scored statistically higher on the survey when compared to chiropractic residents (mean =5.57 vs. 5.25; t=2.12; p=0.04) and to fourth year chiropractic interns (mean = 5.57 vs 5.2; t=2.45; p=0.02). Additionally, with our modified scoring, the sports chiropractors scored 85.3%. A few knowledge gaps were identified in the sample population. Sports chiropractors demonstrated the skills and knowledge to diagnose concussion and excel at identifying the definition and mechanism of concussion, but knowledge gaps regarding diagnosis and management of concussion were found in the sample population.

  4. Hospital Inspections

    Data.gov (United States)

    U.S. Department of Health & Human Services — Welcome to hospitalinspections.org, a website run by the Association of Health Care Journalists (AHCJ) that aims to make federal hospital inspection reports easier...

  5. EFFECT OF THIDIAZURON CONCENTRATION AND APPLICATION PERIOD ON ‘ROYAL GALA’ APPLE FRUITING AND PRODUCTION

    Directory of Open Access Journals (Sweden)

    EVERLAN FAGUNDES

    2017-10-01

    Full Text Available ABSTRACT ‘Gala’ apple trees have low fruit set in restrictive pollination situations, being an obstacle to the achievement of high production rates in orchards in southern Brazil, which can be minimized by the use of growth regulators. The aim of this study was to evaluate the effect of thidiazuron concentrations in ‘Royal Gala’ apple fruiting and production, grown in mild winter conditions. The experiment was conducted during the 2011/2012, 2012/2013 and 2013/2014 crop years in Fraiburgo, SC, on ‘Royal Gala’ apple trees in Marubakaido rootstock M9 with filter. In all evaluation cycles, the experimental design was a randomized block with factorial arrangement (6x2 with six TDZ concentrations and two application forms, with six replicates, and the experimental unit consisting of one plant. The TDZ concentrations of each treatment were applied split into two seasons. The first application was performed on pink bud stage (E2 and the second application was in full bloom stage (F2. The variables evaluated were: fruit set (%, return bloom (%, number and weight of fruits per plant, mean fruit weight (g and average number of seeds per fruit. Data were submitted to analysis of variance, in which for significant variables by the F test, analysis of contrast and polynomial regression were performed in order to evaluate the response of variables with increasing TDZ concentration. TDZ is effective even at low concentrations, increasing the production and fruit set of ‘Gala’ apples in the climatic conditions of southern Brazil.

  6. Antioxidant and protective effects of Royal jelly on histopathological changes in testis of diabetic rats

    Directory of Open Access Journals (Sweden)

    Elham Ghanbari

    2016-08-01

    Full Text Available Background: Diabetes is the most common endocrine disease. It has adverse effects on male reproductive function. Royal Jelly (RJ has antioxidant and anti-diabetic effects and show protective effects against diabetes. Objective: This study was conducted to evaluate the effect of RJ on histopathological alterations of the testicular tissue in streptozotocin (STZ-induced diabetic rats. Materials and Methods: In this experimental study, 28 adult Wistar rats were randomly divided into control (C, royal jelly (R, diabetic (D and RJ-treated diabetic (D+R groups. Diabetes was induced by a single intraperitoneal injection of STZ at 50 mg/kg body weight (BW. The rats from the R and D+R groups received daily RJ (100 mg/kg BW for 6 wks orally. Hematoxylin-Eosin staining was used to analyze histopathological changes including: tunica albuginea thickness (TAT, seminiferous tubules diameter (STsD, Johnsen’s score, tubular differentiation index (TDI, spermiogenesis index (SPI, Sertoli cell index (SCI, meiotic index (MI, and mononuclear immune cells (MICs in testes. The antioxidant status was examined by evaluating testicular levels of ferric reducing antioxidant power (FRAP and catalase (CAT activity. Results: Histological results of the testis from diabetic rats showed significant decrease in STsD, Johnsen’s score, TDI, SPI, SCI and MI, and significant increase in TAT and MICs, while administration of RJ significantly reverted these changes (p<0.05. RJ treatment markedly increased activity of CAT and FRAP. There were significant differences in FRAP levels among C (13.0±0.5, RJ (13.4±0.3, D (7.8±0.6 and D+R (12.4±0.7 groups (p<0.05. Conclusion: RJ improved diabetes-induced impairment in testis, probably through its antioxidant property.

  7. Effect of Royal Jelly on Sterile Wound Healing in Balb/C Mice

    Directory of Open Access Journals (Sweden)

    H Shirzad

    2010-04-01

    Full Text Available Introduction & Objective: Wound healing is the process of repairing following injury to the skin and other soft tissues. Following injury, inflammatory response occurs and the cells below the dermis begin to increase collagen production, later on, the epithelial tissue is regenerated. Royal jelly (RJ is a bee product. There are many reports on pharmacological activity of RJ on experimented animals. The purpose of this study was to investigate the effect of RJ on the induction of wound healing of sterile incision in Balb/C mice. Materials & Methods: In this experimental study which was conducted at Shahr-e-kord University of Medical Sciences in 60 female Balb/C mice (8 weeks old were selected. The mice were anesthetized with ether. The dorsal fur of the animals was shaved and sterilized with alcohol, and then a longitudinal para vertebral full thickness incision of 10mm long was made. The animals were then divided into six equal groups. In group one (negative control, nothing was applied to the wound. Group 2 (positive control was treated with nitrofurazon ointment, group 3 was treated with RJ 200 mg/kg daily, group 4 was treated with RJ 200 mg/kg every two days, group 5 was treated with RJ 300 mg/kg daily, group 6 treated with RJ 300 mg/kg every two days. Royal jelly was topically used on the wounds. The wound length was measured with vernier capilar every two days until the complete healing was occurred. The data were analyzed with SPSS version 11.5 using Kruscal Walis tests. Results: There was a significant difference between groups 1, 2 with the other groups (p0.015. Conclusion: The results of this study indicated that daily application of RJ possesses betters wound healing effects than nitrofurazon.

  8. The functional property of royal jelly 10-hydroxy-2-decenoic acid as a melanogenesis inhibitor.

    Science.gov (United States)

    Peng, Chi-Chung; Sun, Hui-Tzu; Lin, I-Ping; Kuo, Ping-Chung; Li, Jen-Chieh

    2017-08-09

    It has been reported that royal jelly would reduce melanin synthesis and inhibit the expression of melanogensis related proteins and genes. In this study, we evaluate the anti-melanogenic and depigmenting activity of 10-hydroxy-2-decenoic acid (10-HDA) from royal jelly of Apis mellifera. In this study, we assesses the 10-HDA whitening activity in comparison with the changes in the intracellular tyrosinase activity, melanin content and melanin production related protein levles in B16F1 melanoma cells after treating with 10-HDA. Furthermore, the skin whitening effect was evaluated by applying a cream product containing with 0.5%, 1% and 2% of 10-HDA onto the skin of mice (C57BL/6 J) for 3 week to observe the effect of DL*-values. The results showed that 10-HDA inhibited the MITF protein expression (IC50 0.86 mM) in B16F1 melanoma cells. Western blot analysis revealed that 10-HDA inhibited the activity of tyrosinase and the expression of tyrosinase-related protein 1 (TRP-1), TRP-2, and microphthalmia-associated transcription factor (MITF) in B16F1 melanoma cells. In addition, the 10-HDA was applied on the skin of mice show significantly increased the average skin-whitening index (L value). The validation data indicated the potential of 10-HDA for use in suppressing skin pigmentation. The 10-HDA is proposed as a candidate to inhibit melanogenesis, thus it could be developed as cosmetics skin care products.

  9. Hospital marketing.

    Science.gov (United States)

    Carter, Tony

    2003-01-01

    This article looks at a prescribed academic framework for various criteria that serve as a checklist for marketing performance that can be applied to hospital marketing organizations. These guidelines are drawn from some of Dr. Noel Capon of Columbia University's book Marketing Management in the 21st Century and applied to actual practices of hospital marketing organizations. In many ways this checklist can act as a "marketing" balanced scorecard to verify performance effectiveness and develop opportunities for innovation.

  10. Patient‐friendly hospital environments: exploring the patients’ perspective

    Science.gov (United States)

    Douglas, Calbert H.; Douglas, Mary R.

    2004-01-01

    Abstract Objective  To investigate the perceptions and attitudes of patients to the built environments of NHS Trust hospitals, in order to inform design excellence so as to make future hospitals places and spaces responsive to patient needs. Design  An exploratory study of patients perceptions based on qualitative semi‐structured personal interviews. Setting and participants  Fifty one‐to‐one interviews held with hospital in‐patients across the four directorates of surgery, medicine, care of the elderly and maternity at Salford Royal Hospitals NHS Trust, Salford, UK. Results  The research found that there was much similarity in the priorities, issues and concerns raised by patients in each of the four directorates. Patients perceived the built environment of the hospital as a supportive environment. Their accounts in each area pointed to the significance of the factors that immediately impacted on them and their families. Patients identified having a need for personal space, a homely welcoming atmosphere, a supportive environment, good physical design, access to external areas and provision of facilities for recreation and leisure. Responses suggest that patient attitudes and perceptions to the built environment of hospital facilities relates to whether the hospital provides a welcoming homely space for themselves and their visitors that promotes health and wellbeing. Conclusions  The findings have important implications for capital development teams, clinical staff, managers and NHS Estates personnel. Although the study has immediate relevance for Salford Royal Hospitals Trust, findings and recommendations reported provide NHS Estates and other relevant stakeholders with evidence‐based knowledge and understanding of patients’ perceptions and expectations of and preferences for particular facilities and estates provision in NHS hospitals. PMID:14982500

  11. Provision of services for the diagnosis and treatment of heart disease. Fourth report of a Joint Cardiology Committee of the Royal College of Physicians of London and the Royal College of Surgeons of England.

    Science.gov (United States)

    1992-01-01

    The principal conclusions of the fourth report of the Joint Cardiology Committee are: 1 Cardiovascular disease remains a major cause of death and morbidity in the population and of utilisation of medical services. 2 Reduction in the risk of cardiovascular disease is feasible, and better co-ordination is required of strategies most likely to be effective. 3 Pre-hospital care of cardiac emergencies, in particular the provision of facilities for defibrillation, should continue to be developed. 4 There remains a large shortfall in provision of cardiological services with almost one in five district hospitals in England and Wales having no physician with the appropriate training. Few of the larger districts have two cardiologists to meet the recommendation for populations of over 250,000. One hundred and fifty extra consultant posts (in both district and regional centres) together with adequate supporting staff and facilities are urgently needed to provide modest cover for existing requirements. 5 The provision of coronary bypass grafting has expanded since 1985, but few regions have fulfilled the unambitious objectives stated in the Third Joint Cardiology Report. 6 The development of coronary angioplasty has been slow and haphazard. All regional centres should have at least two cardiologists trained in coronary angioplasty and there should be a designated budget. Surgical cover is still required for most procedures and is best provided on site. 7 Advances in the management of arrhythmias, including the use of specialised pacemakers, implantable defibrillators, and percutaneous or surgical ablation of parts of the cardiac conducting system have resulted in great benefit to patients. Planned development of the emerging sub-specialty of arrhythmology is required. 8 Strategies must be developed to limit the increased exposure of cardiologists to ionising radiation which will result from the expansion and increasing complexity of interventional procedures. 9 Supra

  12. Simultaneous high performance liquid chromatographic analysis of vitamins B1, B2 and B6 in royal jelly

    Directory of Open Access Journals (Sweden)

    Presoto Ana Elisa F

    2004-01-01

    Full Text Available Royal jelly is used as a food supplement, popularly known as rich in B vitamins. The present work has two objectives: firstly, to apply simultaneous quantitative determination by High Performance Liquid Chromatography of thiamin (vitamin B1, riboflavin (vitamin B2 and pyridoxine (vitamin B6 and secondly to compare the obtained data with the Dietary Reference Intake (DRI values. The values obtained showed no thiamin, a range from 20 to 171 ng g-1 of riboflavin and from 408 to 2 188 ng g-1 of pyridoxine in royal jelly. According to the Food and Nutrition Board (2000, the DRI of these vitamins varies from 0.2-1.4 mg for thiamin; 0.3-1.6 mg for riboflavin and 0.1-2.0 mg for pyridoxine, depending on age and sex. According to these recommendations, royal jelly is not a good source of vitamins B1, B2 or B6 as these vitamins appear only on order of ng g-1. The proposed method can be used in routine analysis for royal jelly, having the advantage of being simple, fast and reliable.

  13. Royal Decree-Law 12/1982 of 27 August regulating State intervention in the Lemoniz nuclear power plant

    International Nuclear Information System (INIS)

    1982-01-01

    This Royal Decree-Law sets out the conditions of intervention by the State in the achievement of the Lemoniz nuclear power plant with a view to accelerating the work. It sets up an Intervention Council responsible for directing the work which is empowered to take the necessary measures for discharging its duties. (NEA) [fr

  14. 78 FR 23316 - The Royal Bank of Scotland plc, et al.; Notice of Application and Temporary Order

    Science.gov (United States)

    2013-04-18

    ... plc, et al.; Notice of Application and Temporary Order April 12, 2013. AGENCY: Securities and Exchange Commission (``Commission''). ACTION: Temporary order and notice of application for a permanent order under... application for a permanent order. Applicants have also applied for a permanent order. APPLICANTS: The Royal...

  15. Comparative study on the antifungal activity of hydroalcoholic extract of Iranian Propolis and Royal jelly against Rhizopus oryzae

    Directory of Open Access Journals (Sweden)

    Moghim Hassan

    2015-07-01

    Full Text Available Introduction: Mucormycosis is an opportunistic fungal infection. Rhizopus oryzae is major cause of mucormycosis in humans. This disease is the most common form of the acute fungal infection with rapid progress. Iranian Propolis extract and Royal jelly are honey bee products which have been used by human over the past centuries in traditional medicine. In this study the effects of Iranian Propolis and Royal jelly were investigated against Rhizopus oryzae and Candida albicans. Methods: The used method in this study was microdilution. To perform it, the prepared dilutions of Royal jelly and alcoholic extract of Iranian Propolis were added to tubes containing Sabouraud dextrose broth culture media except to control group and then Rhizopus oryzae suspension was added to all microtubes. In the next stage, microtubes were maintained in incubator at 25oC for 48 hours and then 10 ml of the content of each microtube was transferred to Sabouraud dextrose agar media. The minimum inhibitory concentration (MIC and minimum fungicidal concentration (MFC of the agents were calculated. Results: In this study, the MIC and MFC of Iranian Propolis alcoholic extract on Rhizopus oryzae were respectively 0.1 and 0.25 mg/ml and the MFC of Royal jelly on Rhizopus oryzae were respectively 100 ± 34 and 133 ± 46 mg/ml. Conclusion: The results indicate that Propolis might be used as an ideal combination for the treatment of fungal infections like Rhizopus oryzae. However, clinical studies are needed to confirm the effects of these drugs.

  16. [Terhi Kiiskinen. Library of the Finnish nobleman, royal secretary and trustee Henrik Matsson (ca 1540-1617)] / Liivi Aarma

    Index Scriptorium Estoniae

    Aarma, Liivi, 1948-

    2009-01-01

    Arvustus: Kiiskinen, Terhi. Library of the Finnish nobleman, royal secretary and trustee Henrik Matsson (ca 1540-1617). Helsinki, 2004. Terhi Kiiskinen valgustab Forsiuse lugemust temaga seotud ajaloolise isiku Henrik Matsson Hugguti raamatukogu kataloogi abil, mis on säilinud Tallinna Linnaarhiivis

  17. Muusikamaailm : Festivalid Prahas ja Westfalias. Populaarne saksa uusooper. Royal Festival Hall ئ 50. Kaks preemiat Soome. Austusavaldus Mahlerile / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2001-01-01

    Festivalist "Praha kevad" Tšehhis, festivalist Westfälische Musikfest Saksamaal. M. Trojahni ooperist "Enrico". Londoni Royal Festival Hall tähistab avamise 50. aastapäeva. 34. Chicago filmi- ja videofestivalil võitis peapreemia soome dokumentaalfilm "Jean Sibelius ئ naturally". H. Wallen võitis Stuttgardi kammerduode konkursi. Jihlava konservatooriumile Moraavias anti G. Mahleri nimi

  18. Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders.

    Science.gov (United States)

    Malhi, Gin S; Bassett, Darryl; Boyce, Philip; Bryant, Richard; Fitzgerald, Paul B; Fritz, Kristina; Hopwood, Malcolm; Lyndon, Bill; Mulder, Roger; Murray, Greg; Porter, Richard; Singh, Ajeet B

    2015-12-01

    To provide guidance for the management of mood disorders, based on scientific evidence supplemented by expert clinical consensus and formulate recommendations to maximise clinical salience and utility. Articles and information sourced from search engines including PubMed and EMBASE, MEDLINE, PsycINFO and Google Scholar were supplemented by literature known to the mood disorders committee (MDC) (e.g., books, book chapters and government reports) and from published depression and bipolar disorder guidelines. Information was reviewed and discussed by members of the MDC and findings were then formulated into consensus-based recommendations and clinical guidance. The guidelines were subjected to rigorous successive consultation and external review involving: expert and clinical advisors, the public, key stakeholders, professional bodies and specialist groups with interest in mood disorders. The Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders (Mood Disorders CPG) provide up-to-date guidance and advice regarding the management of mood disorders that is informed by evidence and clinical experience. The Mood Disorders CPG is intended for clinical use by psychiatrists, psychologists, physicians and others with an interest in mental health care. The Mood Disorder CPG is the first Clinical Practice Guideline to address both depressive and bipolar disorders. It provides up-to-date recommendations and guidance within an evidence-based framework, supplemented by expert clinical consensus. Professor Gin Malhi (Chair), Professor Darryl Bassett, Professor Philip Boyce, Professor Richard Bryant, Professor Paul Fitzgerald, Dr Kristina Fritz, Professor Malcolm Hopwood, Dr Bill Lyndon, Professor Roger Mulder, Professor Greg Murray, Professor Richard Porter and Associate Professor Ajeet Singh. Professor Carlo Altamura, Dr Francesco Colom, Professor Mark George, Professor Guy Goodwin, Professor Roger McIntyre, Dr Roger Ng

  19. Impact of royal jelly to improve reproductive performance of male rabbits under hot summer conditions

    Directory of Open Access Journals (Sweden)

    A. M. El-Hanoun

    2014-09-01

    Full Text Available To alleviate the deleterious effect of heat stress during summer conditions on male rabbits’ reproduction, 40 V Line adult rabbit bucks (on av. 8 mo old were divided into 4 experimental groups and exposed to temperatures ranging from 23 to 36°C. Bucks in the 1st, 2nd, 3rd, and 4th group were supplemented with 0, 50, 100 or 150 mg of Chinese royal jelly (RJ/kg twice per week, respectively, over a 20-wk period. Semen quality and blood biochemical constituents were evaluated. RJ at any dose exhibited a significant increase (P<0.05 in rabbits’ sperm concentration, total sperm output, sperm motility, live sperm and normal sperm compared to the untreated controls. Plasma total protein, albumin, globulin, glucose and high density lipids (HDL concentrations were significantly (P<0.05 boosted in the RJ groups compared to the controls. In contrast, RJ treatment resulted in a significant (P<0.05 reduction in plasma total lipids, triglycerides, cholesterol and low density lipids (LDL concentrations. Treatment with RJ significantly boosted (P<0.05 testosterone concentration in the RJ groups to reach 110, 120 and 128%, respectively, of the control group. Improved kidney and liver functions were observed in the RJ bucks groups where plasma creatinine, urea concentrations, aspartate aminotransferase and alanine aminotransferase enzyme activities were significantly (P<0.05 decreased by RJ treatments. Treating bucks subjected to heat stress by different RJ doses increased (P<0.05 total antioxidant capacity to 106, 111 and 115% of basal, but significantly reduced (P<0.05 malondialdehyde and thiobarbituric acid reactive substances compared to the untreated. It was concluded that Chinese royal jelly supplementation for heat-stressed male rabbits can counteract summer infertility and improve their physiological status.

  20. 78 FR 76711 - Royal City Charter Coach Lines Ltd.-Acquisition of Control-Quick Coach Lines Ltd. d/b/a Quick...

    Science.gov (United States)

    2013-12-18

    ... current ownership of Quick, and its wholly owned subsidiary Quick Coach Lines USA Inc. (Quick USA... Charter Coach Lines Ltd.--Acquisition of Control-- Quick Coach Lines Ltd. d/b/a Quick Shuttle Service.... SUMMARY: On November 18, 2013, Royal City Charter Coach Lines Ltd. (Royal, or Applicant) filed an...

  1. Alternative sources of supplements in Africanized honeybees submitted to royal jelly production - doi: 10.4025/actascianimsci.v35i2.16976

    Directory of Open Access Journals (Sweden)

    Fabiana Martins Costa-Maia

    2013-03-01

    Full Text Available This study was carried out to evaluate the effect of supplements with isolated soy protein, brewer’s yeast, a mixture of isolated soy protein with brewer’s yeast, linseed oil, palm oil and mixture of linseed oil with palm oil in the royal jelly production of Africanized honey bee colonies. Total royal jelly produced was superior (P

  2. Academic Hospitality

    Science.gov (United States)

    Phipps, Alison; Barnett, Ronald

    2007-01-01

    Academic hospitality is a feature of academic life. It takes many forms. It takes material form in the hosting of academics giving papers. It takes epistemological form in the welcome of new ideas. It takes linguistic form in the translation of academic work into other languages, and it takes touristic form through the welcome and generosity with…

  3. Hospital burden of road traffic injury: major concern in primary and secondary level hospitals in Bangladesh.

    Science.gov (United States)

    Mashreky, S R; Rahman, A; Khan, T F; Faruque, M; Svanström, L; Rahman, F

    2010-04-01

    To assess the burden of road traffic injury (RTI) in primary and secondary level hospitals in Bangladesh, and its economic impact on affected families. Cross-sectional study. The study was carried out in February and March 2001. To estimate the burden of RTI patients and the length of stay in hospital, the discharge records of primary and secondary level hospitals were used as data sources. Records from 16 district hospitals and 45 Upazila health complexes (subdistrict level hospitals), selected at random, were included in this study. A direct interview method was adopted to estimate the patient costs of RTI; this involved interviewing patients or their attendants. In this study, patient costs included money spent by the patient for medicine, transport, food and lodging (including attendants). Approximately 33% of the beds in primary and secondary level hospitals in Bangladesh were occupied by injury-related patients, and more than 19% of the injury patients had been injured in a road traffic accident. People aged 18-45 years were the major victims of RTI, and constituted 70% of the total RTI-related admissions in primary and secondary level hospitals. More than two-thirds of RTI patients were male. The average duration of hospital stay was 5.7 days, and the average patient cost for each RTI patient was US$86 (5834 BDT). RTI is a major cause of hospital admission in Bangladesh, and represents an economic and social burden for the family and the nation. A national strategy and road safety programme need to be developed to reduce the hospital burden and minimize the economic and social impact. 2010 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  4. Hospitality and hostility in hospitals

    DEFF Research Database (Denmark)

    Jensen, Tina Blegind; Aanestad, Margunn

    2007-01-01

    The purpose of this paper is to discuss the adoption of healthcare information systems (HIS) from a user perspective. Our case study concerns how a group of orthopaedic surgeons experienced and reacted to the adoption and mandatory use of an Electronic Patient Record system in a Danish hospital. We...... propose to use the concepts of hospitality and hostility to turn our attention to the interaction between the host (the surgeons) and the guest (the information system) and consider how the boundaries between them evolved in the everyday work practices. As an alternative to previous studies on technology...

  5. Protective effect of royal jelly on the sperm parameters and testosterone level and lipid peroxidation in adult mice treated with oxymetholone

    Directory of Open Access Journals (Sweden)

    Ensieh Zahmatkesh

    2014-01-01

    Full Text Available Objectives: The aim of the present study was to evaluate protective effect of royal jelly on sperm parameters, testosterone level, and malondialdehyde (MDA production in mice. Materials and Methods: Thirty-two adult male NMRI mice weighing 30±2 g were used. All the animals were divided into 4 groups. Control group: received saline 0.1 ml/mouse/day orally for 30 days. Royal Jelly group (RJ: received royal jelly at dose of 100 mg/kg daily for 30 days orally. Oxymetholone group: the received Oxymetholone (OX at dose of 5 mg/kg daily for 30 days orally. Royal Jelly+Oxymetholone group: received royal jelly at dose of 100 mg/kg/day orally concomitant with OX administration. Sperm count, sperm motility, viability, maturity, and DNA integrity were analyzed. Furthermore, serum testosterone and MDA concentrations were determined. Results: In Oxymetholone group, sperm count, motility as well as testosterone concentration reduced significantly (p

  6. Estrogenic Activities of Fatty Acids and a Sterol Isolated from Royal Jelly

    Science.gov (United States)

    Isohama, Yoichiro; Maruyama, Hiroe; Yamada, Yayoi; Narita, Yukio; Ohta, Shozo; Araki, Yoko; Miyata, Takeshi; Mishima, Satoshi

    2008-01-01

    We have previously reported that royal jelly (RJ) from honeybees (Apis mellifera) has weak estrogenic activity mediated by interaction with estrogen receptors that leads to changes in gene expression and cell proliferation. In this study, we isolated four compounds from RJ that exhibit estrogenic activity as evaluated by a ligand-binding assay for the estrogen receptor (ER) β. These compounds were identified as 10-hydroxy-trans-2-decenoic acid, 10-hydroxydecanoic acid, trans-2-decenoic acid and 24-methylenecholesterol. All these compounds inhibited binding of 17β-estradiol to ERβ, although more weakly than diethylstilbestrol or phytoestrogens. However, these compounds had little or no effect on the binding of 17β-estradiol to ERα. Expression assays suggested that these compounds activated ER, as evidenced by enhanced transcription of a reporter gene containing an estrogen-responsive element. Treatment of MCF-7 cells with these compounds enhanced their proliferation, but concomitant treatment with tamoxifen blocked this effect. Exposure of immature rats to these compounds by subcutaneous injection induced mild hypertrophy of the luminal epithelium of the uterus, but was not associated with an increase in uterine weight. These findings provide evidence that these compounds contribute to the estrogenic effect of RJ. PMID:18830443

  7. Estrogenic Activities of Fatty Acids and a Sterol Isolated from Royal Jelly

    Directory of Open Access Journals (Sweden)

    Kazu-Michi Suzuki

    2008-01-01

    Full Text Available We have previously reported that royal jelly (RJ from honeybees (Apis mellifera has weak estrogenic activity mediated by interaction with estrogen receptors that leads to changes in gene expression and cell proliferation. In this study, we isolated four compounds from RJ that exhibit estrogenic activity as evaluated by a ligand-binding assay for the estrogen receptor (ER β. These compounds were identified as 10-hydroxy-trans-2-decenoic acid, 10-hydroxydecanoic acid, trans-2-decenoic acid and 24-methylenecholesterol. All these compounds inhibited binding of 17β-estradiol to ERβ, although more weakly than diethylstilbestrol or phytoestrogens. However, these compounds had little or no effect on the binding of 17β-estradiol to ERα. Expression assays suggested that these compounds activated ER, as evidenced by enhanced transcription of a reporter gene containing an estrogen-responsive element. Treatment of MCF-7 cells with these compounds enhanced their proliferation, but concomitant treatment with tamoxifen blocked this effect. Exposure of immature rats to these compounds by subcutaneous injection induced mild hypertrophy of the luminal epithelium of the uterus, but was not associated with an increase in uterine weight. These findings provide evidence that these compounds contribute to the estrogenic effect of RJ.

  8. The Royal Society of Chemistry and the delivery of chemistry data repositories for the community

    Science.gov (United States)

    Williams, Antony; Tkachenko, Valery

    2014-10-01

    Since 2009 the Royal Society of Chemistry (RSC) has been delivering access to chemistry data and cheminformatics tools via the ChemSpider database and has garnered a significant community following in terms of usage and contribution to the platform. ChemSpider has focused only on those chemical entities that can be represented as molecular connection tables or, to be more specific, the ability to generate an InChI from the input structure. As a structure centric hub ChemSpider is built around the molecular structure with other data and links being associated with this structure. As a result the platform has been limited in terms of the types of data that can be managed, and the flexibility of its searches, and it is constrained by the data model. New technologies and approaches, specifically taking into account a shift from relational to NoSQL databases, and the growing importance of the semantic web, has motivated RSC to rearchitect and create a more generic data repository utilizing these new technologies. This article will provide an overview of our activities in delivering data sharing platforms for the chemistry community including the development of the new data repository expanding into more extensive domains of chemistry data.

  9. Apparent 85Kr ages of groundwater within the Royal watershed, Maine, USA.

    Science.gov (United States)

    Sidle, W C

    2006-01-01

    Specific 85Kr activity is mapped from 264 domestic and municipal wells sampled during 2002-2004 in the Royal watershed (361 km2), Maine. Gas samples are collected at 20 m, 40 m, and > 50 m interval depths within the unconfined aquifers. Gas extraction for 85Kr from wells is obtained directly via a wellhead methodology avoiding conventional collection of large sample volumes. Atmospheric 85Kr input to the recharge environment is estimated at 1.27 Bq m(-3) by time-series analyses of weighted monthly precipitation (2001-2004). Numerical simulation of Kr gas transport through the variable unsaturated zones to the water table suggests up to 12-year time lags locally, thus biasing the 85Kr groundwater ages. Apparent 85Kr ages suggest that approximately 70% of groundwater near 20 m depth was recharged less than 30 years BP (2004). Mass-age transport modeling suggests that post mid-1950s recharge penetrates to part of the basin's floor and that older groundwater seeps from the underlying fractured bedrock may occur.

  10. The nuclear engineering programmes at the Royal Military College of Canada. Part I

    Energy Technology Data Exchange (ETDEWEB)

    Bonin, H.W. [Royal Military College of Canada, Dept. of Chemistry and Chemical Engineering, Kingston, Ontario (Canada)

    2002-05-01

    The last years have been eventful for the staff and students in the nuclear engineering programmes at the Royal Military College of Canada (RMC) in Kingston, Ontario. Among the several changes is the accessibility of the graduate programmes to civilian (Canadian citizens) students, a fact that is little known outside RMC since, in the past, these graduate programmes were intended only for military personnel. Another major event is the accreditation of the graduate programmes offered by the Department of Chemistry and Chemical Engineering(chemical, nuclear and environmental science and engineering) by the Ontario Council of Graduate Studies. The teaching and research staff share the following research areas: radiochemistry and neutron activation analysis, radiation effects on materials, radiation processing of polymers, neutron radiography, nuclear reactor simulation, analysis and design, CANDU fuel bundle optimal design, nuclear fuel cycles and management, nuclear fuel engineering and behaviour, including fission product release modelling, artificial intelligence applications to nuclear systems, nuclear accident response, nuclear radiation detection and measurement, health physics, dosimetry and radiation protection and nuclear reactor control.

  11. Conservation of Stone Cladding on the FAÇADE of Royal Palace in Caserta

    Science.gov (United States)

    Titomanlio, I.

    2013-07-01

    The beauty of cultural heritage and monumental architecture, is often linked to their non-structural elements and decorative stones façades cladding. The collapse of these elements causes significant consequences that interest the social, the economic, the historical and the technical fields. Several regulatory documents and literature studies contain methods to address the question of relief and of the risk analysis and due to the non - structural stones security. Among the references are widespread international regulatory documents prepared by the Federal Emergency Management Agency of the United States by Applied Technology Council and California. In Italy there are some indications contained in the Norme Tecniche per le Costruzioni and the Direttiva del Presidente del Consiglio dei Ministri in 2007, finalize to the reduction of seismic risk assessment of cultural heritage. The paper, using normative references and scientific researches, allows to analyze on Royal Palace of Caserta the safety and the preservation of cultural heritage and the vulnerability of non-structural stones façade cladding. Using sophisticated equipments of Laboratory ARS of the Second University of Naples, it was possible to analyze the collapse of stone elements due to degradation caused by natural phenomena of deterioration (age of the building, type of materials, geometries , mode of fixing of the elements themselves). The paper explains the collapse mechanisms of stones façade cladding of Luigi Vanvitelli Palace.

  12. Reel Royal Diversity? The Glass Ceiling in Disney’s Mulan and Princess and the Frog

    Directory of Open Access Journals (Sweden)

    Lauren Dundes

    2016-12-01

    Full Text Available Both in Mulan and Princess and the Frog, Disney eschews a traditional fairytale ending involving palatial opulence by substituting an alternative narrative for women of color. Mulan disguises herself as a male soldier in order to serve in her father’s place. After sharing victory with male companions, she willingly returns home to domesticity and the confines imposed by her gender. Tiana spends two thirds of the movie as a frog, substantially limiting her on-screen time as an African American female. Like Mulan, she is driven to please her father. She fulfills his dream of owning a high-end restaurant, ironically named Tiana’s Palace, the closest she comes to a royal lifestyle. Although protagonists with more realistic lives could potentially enhance viewers’ connection with them and model a work ethic or commitment to home life, the standard and more financially successful Disney narrative immerses viewers in a fantasy world of endless prospects including a life of royalty. These nonwhite heroines instead display a willingness to settle for more modest aspirations in stories replete with stereotypical gender and race-bound tropes. This divergent narrative suggests that protagonists of color are not entitled to a life of leisure and privilege that white Disney princesses enjoy.

  13. Royal Policy and the Transfer ot the Consulado under the Old Regime

    Directory of Open Access Journals (Sweden)

    Allan J. KUETHE

    2017-11-01

    Full Text Available The abrupt transfer of the Casa de la Contratación and the Consulado de Cargadores a Indias from Seville to Cádiz in 1717 opened a political struggle between the two cities that would not be completely resolved until the enlightened absolutism of the Marqués de la Ensenada imposed its will. This struggle witnessed old regime politics at both their best and their worst. The present work seeks to analyze the several manifestations of this competition as well as the broader settings in which they occurred. While the new absolutism first appeared through the abad Alberoni in the original transfer and again through its affirmation by the duque de Ripperdá, with the hand of Queen Isabel not far beneath the surface, the traditional culture of consultation and compromise would eventually emerge and permit Seville to retain important powers until much later. Then, in a new era with much different priorities, which were heavily influenced by the coming of the War of the Asiento, royal absolutism as personified by Ensenada and his immediate predecessors would strip Sevilla of its remaining rights and at long last complete the transfer that had begun over twenty-six years before. 

  14. Enhancements to the SLOWPOKE-2 nuclear research reactor at the Royal Military College of Canada

    Energy Technology Data Exchange (ETDEWEB)

    Hungler, P.C.; Andrews, M.T.; Weir, R.D.; Nielson, K.S.; Chan, P.K.; Bennett, L.G.I., E-mail: paul.hungler@rmc.ca [Royal Military College of Canada, Kingston, Ontario (Canada)

    2014-07-01

    In 1985 a Safe Low Power C(K)ritical Experiment (SLOWPOKE) nuclear research reactor was installed at the Royal Military College of Canada (RMCC). The reactor at nominally 20 kW thermal was named SLOWPOKE-2 and the core was designed to have a total of 198 fuel pins with Low Enriched Uranium (LEU) fuel (19.89% U-235). Installation of the reactor was intended to provide an education tool for members of the Canadian Armed Forces (CAF) and an affordable neutron source for the application of neutron activation analysis (NAA) and radioisotope production. Today, the SLOWPOKE-2 at RMCC continues to be a key education tool for undergraduate and post-graduate students and successfully conducts NAA and isotope production as per its original design intent. RMCC has significantly upgraded the facility and instruments to develop capabilities such as delayed neutron and gamma counting (DNGC) and neutron imaging, including 2D thermal neutron radiography and 3D thermal neutron tomography. These unique nuclear capabilities have been applied to relevant issues in the CAF. The analog control system originally installed in 1985 has been removed and replaced in 2001 by the SLOWPOKE Integrated Reactor Control and Instrumentation System (SIRCIS) which is a digital controller. This control system continues to evolve with SIRCIS V2 currently in operation. The continual enhancement of the facility, instruments and systems at the SLOWPOKE-2 at RMCC will be discussed, including an update on RMCC's refueling plan. (author)

  15. Longevity extension of worker honey bees (Apis mellifera by royal jelly: optimal dose and active ingredient

    Directory of Open Access Journals (Sweden)

    Wenchao Yang

    2017-03-01

    Full Text Available In the Western honey bee, Apis mellifera, queens and workers have different longevity although they share the same genome. Queens consume royal jelly (RJ as the main food throughout their life, including as adults, but workers only eat worker jelly when they are larvae less than 3 days old. In order to explore the effect of RJ and the components affecting longevity of worker honey bees, we first determined the optimal dose for prolonging longevity of workers as 4% RJ in 50% sucrose solution, and developed a method of obtaining long lived workers. We then compared the effects of longevity extension by RJ 4% with bee-collected pollen from rapeseed (Brassica napus. Lastly, we determined that a water soluble RJ protein obtained by precipitation with 60% ammonium sulfate (RJP60 contained the main component for longevity extension after comparing the effects of RJ crude protein extract (RJCP, RJP30 (obtained by precipitation with 30% ammonium sulfate, and RJ ethanol extract (RJEE. Understanding what regulates worker longevity has potential to help increase colony productivity and improve crop pollination efficiency.

  16. Longevity extension of worker honey bees (Apis mellifera) by royal jelly: optimal dose and active ingredient.

    Science.gov (United States)

    Yang, Wenchao; Tian, Yuanyuan; Han, Mingfeng; Miao, Xiaoqing

    2017-01-01

    In the Western honey bee, Apis mellifera , queens and workers have different longevity although they share the same genome. Queens consume royal jelly (RJ) as the main food throughout their life, including as adults, but workers only eat worker jelly when they are larvae less than 3 days old. In order to explore the effect of RJ and the components affecting longevity of worker honey bees, we first determined the optimal dose for prolonging longevity of workers as 4% RJ in 50% sucrose solution, and developed a method of obtaining long lived workers. We then compared the effects of longevity extension by RJ 4% with bee-collected pollen from rapeseed ( Brassica napus ). Lastly, we determined that a water soluble RJ protein obtained by precipitation with 60% ammonium sulfate (RJP 60 ) contained the main component for longevity extension after comparing the effects of RJ crude protein extract (RJCP), RJP 30 (obtained by precipitation with 30% ammonium sulfate), and RJ ethanol extract (RJEE). Understanding what regulates worker longevity has potential to help increase colony productivity and improve crop pollination efficiency.

  17. Royal Society of Canada expert panel report : environmental and health impacts of Canada's oil sands industry

    International Nuclear Information System (INIS)

    Gosselin, P.; Hrudey, S.E.; Naeth, M.A.; Plourde, A.; Therrien, R.; Laval Univ., Quebec City, PQ; Van Der Kraak, G.; Guelph Univ., ON; Xu, Z.

    2010-12-01

    This expert panel report was commissioned by the Royal Society of Canada to provide a comprehensive evidence-based assessment of the environmental and health impacts of Canada's oil sands industry. The report evaluated the feasibility of land reclamation and the impacts of oil sands contaminants on downstream residents. Health impacts on residents living in the Regional Municipality of Wood Buffalo were assessed, and the impacts on regional water supplies were evaluated. Regional water and ground water quantities were examined, and issues related to tailing pond operations and reclamation were examined. Ambient air quality impacts were assessed, as well as potential impacts of the oil sands industry on greenhouse gas (GHG) emissions. The environmental regulatory performance of operators in the industry was also evaluated. A summary of economic and policy issues related to the industry was also provided. The study identified major gaps in the process of assessment, prevention, and mitigation of the health impacts of oil sands exploitation, as as major indirect health impacts linked to past exploitation activities. 672 refs., 11 tabs., 11 figs. 10 appendices.

  18. Protective Role of Royal Jelly in Oxymetholone-induced Oxidative Injury in Mouse Testis

    Directory of Open Access Journals (Sweden)

    Gholamreza Najafi

    2014-06-01

    Full Text Available Background: An adverse effect of oxymetholone (OXM, an anabolic-androgenic steroid used as energetic medicine, is reproductive toxicity. Royal jelly (RJ is an efficient antioxidant that has been used to treat reproductive problems. In this study, we investigated the effects of RJ on OXM-induced oxidative injuries in mouse testes. Methods: Male mice were divided into four groups. Two groups of mice were administered OXM (5 mg/kg/day, p.o. for 28 days. One of these groups received RJ (100 mg/kg/day, p.o. concurrently. A vehicle-treated control group and a RJ control group were also included. Results: The OXM-treated group showed a significant decrease in the serum testosterone concentration and spermatogenic activities, along with many histological alterations. OXM treatment also caused a significant decrease in catalase activity with an increase in lipid peroxidation in the mouse testes. The above-noted parameters were restored to near normal levels by RJ co-administration. Conclusion: The results demonstrate that RJ protects against OXM-induced reproductive toxicities.

  19. Noise exposure and cognitive performance: A study on personnel on board Royal Norwegian Navy vessels

    Directory of Open Access Journals (Sweden)

    Kaja Irgens-Hansen

    2015-01-01

    Full Text Available Prior research shows that work on board vessels of the Royal Norwegian Navy (RNoN is associated with noise exposure levels above recommended standards. Further, noise exposure has been found to impair cognitive performance in environmental, occupational, and experimental settings, although prior research in naval and maritime settings is sparse. The aim of this study was to evaluate cognitive performance after exposure to noise among personnel working on board vessels in the RNoN. Altogether 87 Navy personnel (80 men, 7 women; 31 ± 9 years from 24 RNoN vessels were included. Noise exposure was recorded by personal noise dosimeters at a minimum of 4 h prior to testing, and categorized into 4 groups for the analysis: 85.2 dB(A. The participants performed a visual attention test based on the Posner cue-target paradigm. Multivariable general linear model (GLM analyses were performed to analyze whether noise exposure was associated with response time (RT when adjusting for the covariates age, alertness, workload, noise exposure in test location, sleep the night before testing, use of hearing protection device (HPD, and percentage of errors. When adjusting for covariates, RT was significantly increased among personnel exposed to >85.2 dB(A and 77.1-85.2 dB(A compared to personnel exposed to <72.6 dB(A.

  20. The Lyophilization Process Maintains the Chemical and Biological Characteristics of Royal Jelly

    Directory of Open Access Journals (Sweden)

    Andresa Piacezzi Nascimento

    2015-01-01

    Full Text Available The alternative use of natural products, like royal jelly (RJ, may be an important tool for the treatment of infections caused by antibiotic-resistant bacteria. RJ presents a large number of bioactive substances, including antimicrobial compounds. In this study, we carried out the chemical characterization of fresh and lyophilized RJ and investigated their antibacterial effects with the purpose of evaluating if the lyophilization process maintains the chemical and antibacterial properties of RJ. Furthermore, we evaluated the antibacterial efficacy of the main fatty acid found in RJ, the 10-hydroxy-2-decenoic acid (10H2DA. Chromatographic profile of the RJ samples showed similar fingerprints and the presence of 10H2DA in both samples. Furthermore, fresh and lyophilized RJ were effective against all bacteria evaluated; that is, the lyophilization process maintains the antibacterial activity of RJ and the chemical field of 10H2DA. The fatty acid 10H2DA exhibited a good antibacterial activity against Streptococcus pneumoniae. Therefore, it may be used as an alternative and complementary treatment for infections caused by antibiotic-resistant S. pneumoniae.

  1. The nuclear engineering programmes at the Royal Military College of Canada. Part I

    International Nuclear Information System (INIS)

    Bonin, H.W.

    2002-01-01

    The last years have been eventful for the staff and students in the nuclear engineering programmes at the Royal Military College of Canada (RMC) in Kingston, Ontario. Among the several changes is the accessibility of the graduate programmes to civilian (Canadian citizens) students, a fact that is little known outside RMC since, in the past, these graduate programmes were intended only for military personnel. Another major event is the accreditation of the graduate programmes offered by the Department of Chemistry and Chemical Engineering(chemical, nuclear and environmental science and engineering) by the Ontario Council of Graduate Studies. The teaching and research staff share the following research areas: radiochemistry and neutron activation analysis, radiation effects on materials, radiation processing of polymers, neutron radiography, nuclear reactor simulation, analysis and design, CANDU fuel bundle optimal design, nuclear fuel cycles and management, nuclear fuel engineering and behaviour, including fission product release modelling, artificial intelligence applications to nuclear systems, nuclear accident response, nuclear radiation detection and measurement, health physics, dosimetry and radiation protection and nuclear reactor control

  2. Enhancements to the SLOWPOKE-2 nuclear research reactor at the Royal Military College of Canada

    International Nuclear Information System (INIS)

    Hungler, P.C.; Andrews, M.T.; Weir, R.D.; Nielson, K.S.; Chan, P.K.; Bennett, L.G.I.

    2014-01-01

    In 1985 a Safe Low Power C(K)ritical Experiment (SLOWPOKE) nuclear research reactor was installed at the Royal Military College of Canada (RMCC). The reactor at nominally 20 kW thermal was named SLOWPOKE-2 and the core was designed to have a total of 198 fuel pins with Low Enriched Uranium (LEU) fuel (19.89% U-235). Installation of the reactor was intended to provide an education tool for members of the Canadian Armed Forces (CAF) and an affordable neutron source for the application of neutron activation analysis (NAA) and radioisotope production. Today, the SLOWPOKE-2 at RMCC continues to be a key education tool for undergraduate and post-graduate students and successfully conducts NAA and isotope production as per its original design intent. RMCC has significantly upgraded the facility and instruments to develop capabilities such as delayed neutron and gamma counting (DNGC) and neutron imaging, including 2D thermal neutron radiography and 3D thermal neutron tomography. These unique nuclear capabilities have been applied to relevant issues in the CAF. The analog control system originally installed in 1985 has been removed and replaced in 2001 by the SLOWPOKE Integrated Reactor Control and Instrumentation System (SIRCIS) which is a digital controller. This control system continues to evolve with SIRCIS V2 currently in operation. The continual enhancement of the facility, instruments and systems at the SLOWPOKE-2 at RMCC will be discussed, including an update on RMCC's refueling plan. (author)

  3. Hearing loss in the royal Norwegian Navy: a cross-sectional study.

    Science.gov (United States)

    Irgens-Hansen, Kaja; Sunde, Erlend; Bråtveit, Magne; Baste, Valborg; Oftedal, Gunnhild; Koefoed, Vilhelm; Lind, Ola; Moen, Bente Elisabeth

    2015-07-01

    Prior studies have indicated a high prevalence of noise-induced hearing loss (NIHL) among Navy personnel; however, it is not clear whether this is caused by work on board. The present study aimed to assess the prevalence of hearing loss among Navy personnel in the Royal Norwegian Navy (RNoN), and to investigate whether there is an association between work on board RNoN vessels and occurrence of hearing loss. Navy personnel currently working on board RNoN vessels were recruited to complete a questionnaire on noise exposure and health followed by pure tone audiometry. Hearing loss was defined as hearing threshold levels ≥25 dB in either ear at the frequencies 3,000, 4,000 or 6,000 Hz. Hearing thresholds were adjusted for age and gender using ISO 7029. The prevalence of hearing loss among Navy personnel was 31.4 %. The work exposure variables: years of work in the Navy, years on vessel(s) in the Navy and years of sailing in the Navy were associated with reduced hearing after adjusting for age, gender and otitis as an adult. Among the work exposure variables, years of sailing in the Navy was the strongest predictor of reduced hearing, and significantly reduced hearing was found at the frequencies 1,000, 3,000 and 4,000 Hz. Our results indicate that time spent on board vessels in the RNoN is a predictor of reduced hearing.

  4. Noise exposure and cognitive performance: A study on personnel on board Royal Norwegian Navy vessels.

    Science.gov (United States)

    Irgens-Hansen, Kaja; Gundersen, Hilde; Sunde, Erlend; Baste, Valborg; Harris, Anette; Bråtveit, Magne; Moen, Bente E

    2015-01-01

    Prior research shows that work on board vessels of the Royal Norwegian Navy (RNoN) is associated with noise exposure levels above recommended standards. Further, noise exposure has been found to impair cognitive performance in environmental, occupational, and experimental settings, although prior research in naval and maritime settings is sparse. The aim of this study was to evaluate cognitive performance after exposure to noise among personnel working on board vessels in the RNoN. Altogether 87 Navy personnel (80 men, 7 women; 31 ± 9 years) from 24 RNoN vessels were included. Noise exposure was recorded by personal noise dosimeters at a minimum of 4 h prior to testing, and categorized into 4 groups for the analysis: 85.2 dB(A). The participants performed a visual attention test based on the Posner cue-target paradigm. Multivariable general linear model (GLM) analyses were performed to analyze whether noise exposure was associated with response time (RT) when adjusting for the covariates age, alertness, workload, noise exposure in test location, sleep the night before testing, use of hearing protection device (HPD), and percentage of errors. When adjusting for covariates, RT was significantly increased among personnel exposed to >85.2 dB(A) and 77.1-85.2 dB(A) compared to personnel exposed to <72.6 dB(A).

  5. "Inhumanly brought back to life and misery": Mary Wollstonecraft, Frankenstein, and the Royal Humane Society.

    Science.gov (United States)

    Williams, C

    2001-01-01

    While thorough investigation of many aspects of contemporary scientific developments and Mary Shelley's personal history have provided illuminating contexts for the study of Frankenstein, the activities of the Royal Humane Society, and other bodies and individuals who pioneered and publicized resuscitation techniques, have been comparatively neglected. Here we find a richly documented, highly conspicuous area of scientific endeavour, which generated much excitement in life and literature from the last quarter of the eighteenth century onwards. There are three major points of contact with Frankenstein: Victor Frankenstein's revival of dead tissue to make his creature; the frequent occurrences of unconsciousness and asphyxia, both in the novel and in Mary Shelley's family during the period leading up to its composition, and the widely differing degrees of competence and success with which they are treated; and the possibility that resuscitative techniques were used to revive Mary Shelley's mother, Mary Wollstonecraft, after a suicide attempt. The impact on Frankenstein of Mary Shelley's lifelong distress at the role she played in bringing about her mother's death in childbirth has been thoroughly canvassed by other critics, notably Anne Mellor, but the thought that Mary Shelley, who was herself conceived after her mother's second suicide attempt, might be, in a sense, a child of the dead adds a further turn to the Gothic screw. This study traces a hitherto unexplored intersection between Mary Shelley's first novel and her family history, as well as showing how it launches a formidable attack on the shady ethics and inconsiderate arrogance of some early resuscitators.

  6. Changes in Alternative Splicing in Apis Mellifera Bees Fed Apis Cerana Royal Jelly

    Directory of Open Access Journals (Sweden)

    Shi Yuan Yuan

    2014-12-01

    Full Text Available The Western honey bee (Apis mellifera is a social insect characterized by caste differentiation in which the queen bee and worker bees display marked differences in morphology, behavior, reproduction, and longevity despite their identical genomes. The main causative factor in caste differentiation is the food fed to queen larvae, termed royal jelly (RJ. Alternative splicing (AS is an important RNA-mediated post-transcriptional process in eukaryotes. Here we report AS changes in A. mellifera after being fed either A. mellifera RJ or A. cerana RJ. The results demonstrated that the RJ type affected 4 types of AS in adult A. mellifera: exon skipping, intron retention, alternative 5’ splice sites, and alternative 3’splice sites. After feeding with A. cerana RJ, AS occurred in many genes in adult A. mellifera that encode proteins involved in development, growth, the tricarboxylic acid cycle, and substance metabolism. This study provides the first evidence that heterospecific RJ can influence the AS of many genes related to honey bee development and growth.

  7. Protective Effect of Royal Jelly against Renal Damage in Streptozotocin Induced Diabetic Rats

    Directory of Open Access Journals (Sweden)

    Elham Ghanbari

    2015-03-01

    Full Text Available Background: Royal jelly has been shown to have antioxidant and antidiabetic effects. The objective of this study was to evaluate the protective effect of RJ against kidney damage in streptozotocin induced diabetic rats. Methods: Thirty two male Wistar rats were divided randomly into four groups (n=8 per group. Normal control and diabetic control groups received 1cc/day distilled water, normal RJ-treated and diabetic RJ-treated groups received 100mg RJ/kg body weight daily. Diabetes was induced by intraperitoneal injection of streptozotocin. At the end of the experiment, urine and kidney samples were collected for biochemical and histopathological analysis. Results: The results showed that diabetes could increase levels of urine urea, total protein and albumin significantly, and could decrease the levels of creatinine and uric acid in urine. In the kidney tissue homogenates, catalase activity and antioxidant power were significantly lower, whereas malondialdehyde levels were significantly higher in diabetic group when compared with control group. Diabetic rats showed severe histological changes in kidney tissues. Treatment of diabetic rats with RJ improved significantly all of these parameters. Conclusion: The present study revealed that treatment with RJ resulted in significant improvement in histopathological alterations in kidney tissue and urine parameters of diabetic rats. This could be due to its antioxidant activity and the ability of RJ for scavenging the free radicals released in diabetes. These findings suggest that RJ has protective effects on kidneys affected by diabetes mellitus.

  8. The protective effect of Royal Jelly against the hemopoiesis dysfunction in X-irradiated mice

    Energy Technology Data Exchange (ETDEWEB)

    Emori, Yutaka; Oka, Hideki; Ohya, Osamu; Tamaki, Hajime; Hayashi, Yoshiro [Zeria Pharmaceutical Co., Ltd., Konan, Saitama (Japan). Central Research Laboratories; Nomoto, Kikuo

    1998-02-01

    The protective effect of Royal Jelly (RJ) against the hemopoietic dysfunction in whole body X-irradiated C57BL/6 mice was investigated. When RJ (1.0 g/kg, po or 0.5 g/kg, ip) was administered every day beginning two weeks before X-irradiation (10 Gy), a significant increase in the number of leukocytes and erythrocytes was observed in mice treated with RJ, as compared with X-irradiated control. In addition, the number of colony forming units in culture (CFU-C) of bone marrow cells or splenocytes was significantly increased in mice treated with RJ. Therefore, when granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-3 (IL-3) in peripheral blood was measured by ELISA kit, a significant increase in the amount of GM-CSF and IL-3 was observed. These results suggest that the protective effect of RJ against hemopoietic dysfunction could be expressed through an increase in the number of hemopoietic stem cells by the induction of hemopoietic factor such as GM-CSF and IL-3. (author)

  9. In Vitro Anti-Inflammatory Effects of Three Fatty Acids from Royal Jelly

    Directory of Open Access Journals (Sweden)

    Yi-Fan Chen

    2016-01-01

    Full Text Available Trans-10-hydroxy-2-decenoic acid (10-H2DA, 10-hydroxydecanoic acid (10-HDAA, and sebacic acid (SEA are the three major fatty acids in royal jelly (RJ. Previous studies have revealed several pharmacological activities of 10-H2DA and 10-HDAA, although the anti-inflammatory effects and underlying mechanisms by which SEA acts are poorly understood. In the present study, we evaluated and compared the in vitro anti-inflammatory effects of these RJ fatty acids in lipopolysaccharide-stimulated RAW 264.7 macrophages. The results showed that 10-H2DA, 10-HDAA, and SEA had potent, dose-dependent inhibitory effects on the release of the major inflammatory-mediators, nitric oxide, and interleukin-10, and only SEA decreased TNF-α production. Several key inflammatory genes have also been modulated by these RJ fatty acids, with 10-H2DA showing distinct modulating effects as compared to the other two FAs. Furthermore, we found that these three FAs regulated several proteins involved in MAPK and NF-κB signaling pathways. Taken together, these findings provide additional references for using RJ against inflammatory diseases.

  10. The Effects of Royal Jelly on Fitness Traits and Gene Expression in Drosophila melanogaster.

    Directory of Open Access Journals (Sweden)

    John R Shorter

    Full Text Available Royal Jelly (RJ is a product made by honey bee workers and is required for queen differentiation and accompanying changes in queen body size, development time, lifespan and reproductive output relative to workers. Previous studies have reported similar changes in Drosophila melanogaster in response to RJ. Here, we quantified viability, development time, body size, productivity, lifespan and genome wide transcript abundance of D. melanogaster reared on standard culture medium supplemented with increasing concentrations of RJ. We found that lower concentrations of RJ do induce significant differences in body size in both sexes; higher concentrations reduce size, increase mortality, shorten lifespan and reduce productivity. Increased concentrations of RJ also consistently lengthened development time in both sexes. RJ is associated with changes in expression of 1,581 probe sets assessed using Affymetrix Drosophila 2.0 microarrays, which were enriched for genes associated with metabolism and amino acid degradation. The transcriptional changes are consistent with alterations in cellular processes to cope with excess nutrients provided by RJ, including biosynthesis and detoxification, which might contribute to accelerated senescence and reduced lifespan.

  11. Determination of amino acids and protein content in fresh and commercial royal jelly from Bulgaria

    Directory of Open Access Journals (Sweden)

    R. Balkanska

    2015-10-01

    Full Text Available Royal jelly (RJ is popular among consumers around the world due to its perceived health benefits. The purpose of this study was to assess the levels of free and total amino acid profile as well as protein content in order to characterize Bulgarian RJ samples. A total of 17 fresh and commercial RJ samples from different regions of Bulgaria were analyzed. The results obtained show that proline (Pro, lysine (Lys, methionine (Met, aspartic acid (Asp, cysteine (Cys, histidine (His were major free amino acids (FAAs in RJ. The average content of Pro was 2.3 mg/g. The FAA content ranged from 5.5 to 6.2 mg/g of RJ. The most abundant total amino acids (TAAs were aspartic acid (Asp, glutamic acid (Glu, lysine (Lys, leucine (Leu, serine (Ser and proline (Pro. The average TAA content in fresh and commercial RJ were 129±10 and 114±8 mg/g, respectively. The results obtained for TAA content were used to establish a range for amino acid composition of Bulgarian RJ. The content of proteins was higher in fresh RJ than in commercial samples and this difference was significant (p<0.05. The following ranges were observed for fresh and commercial samples 14.7–17.3 and 12.5–14.9 mg/g, respectively. DOI: http://dx.doi.org/10.4314/bcse.v29i3.16

  12. The dreams of a cancer patient: a "royal road" to understanding the somatic illness.

    Science.gov (United States)

    Calogeras, R C; Alston, T M

    2000-12-01

    In this paper we have presented the principal dreams of a 39-year-old female patient in order to demonstrate how closely the dreams were linked with the understanding of her cancerous condition. The analysis, lasting over a period of eight years, ended with the remission of the patient's cancerous condition to the point where she was without pain and symptom-free. The findings suggested that her dreams played a special role in her analysis by providing important landmarks regarding her treatment's progress and state of her cancerous condition. In a general sense, it was concluded that the patient's dreams did provide a "royal road" to understanding her somatic illness. Specifically, it was concluded that, first, the patient's dreams were able to represent quite reliably, in symbolic form, the state of her cancerous condition; second, that the cancer condition and transference-countertransference reactions were closely entwined; and third, that each of the patient's dreams seemed to be introduced by a crisis situation connected with a traumatic early memory.

  13. Heritage Landmark of the Royal Town of Klang: Balai Bomba Klang Selatan

    Science.gov (United States)

    Sulaiman, Normah; Powell, Robert

    2017-10-01

    The arrival of the British colony in Kuala Lumpur sparked a radical change in the town in terms of infrastructure and town planning. Due to the British Empire’s reign over Malaya in the advent of 20th century, the colonial architectural style has influenced a lot of important building in the royal town of Selangor. Some of the building is abandoned disrespect, disregard and it’s frightening. Many deemed historic buildings and structures disappears in exchange for modernity, which is a threat to the townscape and history. The local council of Klang aims to preserve clusters of colonial sights, place of worships, schools, and remnants of a fort that has shaped the town enabling people to be more appreciative towards it. Located in the heart of Klang town, the fire station sits next to another heritage trail icon, Raja Abdullah Warehouse. Without proper documentation and curation, the building significant will remain unknown and eventually disappear. The core of this paper will showcase the building design quality and its importance, as the first attempt to document the Balai Bomba Klang Selatan to assist in conserving its tangible and intangible qualities. The study aims to collate and document the tangible qualities of the fire station to complement the measured drawing exercise.

  14. Impact of an antimicrobial stewardship intervention on appropriateness of prescribing for community-acquired pneumonia in an Australian regional hospital.

    Science.gov (United States)

    Bond, Stuart E; Boutlis, Craig S; Yeo, Wilfred W; Miyakis, Spiros

    2017-05-01

    Community-acquired pneumonia (CAP) is the second commonest indication for antibiotic use in Australian hospitals and is therefore a frequent target for antimicrobial stewardship. A single-centre prospective study was conducted in a regional referral hospital comparing management of adult patients with CAP before and after an educational intervention. We demonstrated a reduction in duration of therapy and reduced inappropriate use of ceftriaxone-based regimens for non-severe CAP. © 2017 Royal Australasian College of Physicians.

  15. A tertiary hospital audit of the use of medical imaging in the 24 h preceding death.

    Science.gov (United States)

    Liu, D; Weil, J; Boughey, M; Sutherland, T

    2016-02-01

    This study aims to investigate the number, modality and indication for imaging studies performed on acute hospital inpatients in the 24 h prior to death. Data were obtained from retrospective analysis of deceased patients from a university affiliated tertiary hospital over a 2-year period and it was found that around one in five inpatients received medical imaging in the last 24 h of their life (364 of 1855, 19.6%). © 2016 Royal Australasian College of Physicians.

  16. Hospital Malnutrition

    OpenAIRE

    Asumadu-Sarkodie, Samuel

    2012-01-01

    Malnutrition seen in hospitals usually occurs as some form of protein-energy malnutrition (PEM). Primary PEM results from an acute or chronic deficiency of both protein and calories. Secondary PEM, or cachexia, results from a disease or medical condition such as cancer or gastrointestinal disease that alters requirements or impairs utilization of nutrients. This record was migrated from the OpenDepot repository service in June, 2017 before shutting down.

  17. Royal Order of 21 August 1985 amending the Royal Order of 28 February 1963 enacting General Regulations for Protection of the Population and Workers against the Hazards of Ionizing Radiation

    International Nuclear Information System (INIS)

    1985-01-01

    The amendments to the 1963 Royal Order aim to improve the prior licensing procedure for products containing radioisotopes to be used as unsealed sources in human or veterinary medicine for ''in vivo'' or ''in vitro'' diagnostic purposes and for therapy. They concern, in particular, the preparation of the licensing file, quality control procedures and the laboratories approved to perform such controls. The Ministerial Order of 13th April 1984 which contained similar provisions is revoked. (NEA) [fr

  18. Manutenção da qualidade pós-colheita de maçãs 'Royal Gala' e 'Galaxy' sob armazenamento em atmosfera controlada Postharvest quality maintenance of 'Royal Gala' and 'Galaxy' apples stored under controlled atmosphere

    Directory of Open Access Journals (Sweden)

    Auri Brackmann

    2008-12-01

    Full Text Available O objetivo deste trabalho foi avaliar a eficiência de condições de atmosfera controlada na conservação de maçãs 'Royal Gala' e 'Galaxy'. O delineamento utilizado foi o inteiramente casualizado com quatro repetições e unidade experimental composta por 25 frutos. Os tratamentos utilizados se originaram da combinação de duas culivares ('Royal Gala' e 'Galaxy' e sete diferentes condições de armazenamento, que foram: [1] Armazenamento refrigerado (AR; [2] 1,0kPa O2 + 2,0kPa CO2; [3] 1,0kPa O2 + 2,5kPa CO2; [4] 1,0kPa O2 + 3,0kPa CO2; [5] 0,8kPa O2 + 2,5kPa CO2; [6] 1,2kPa O2 + 2,5kPa CO2 e [7] 1,0kPa O2 + 2,5 kPa CO2. A temperatura nos tratamentos 1 ao 6 foi de +0,5°C e no tratamento 7, -0,5°C As avaliações foram realizadas após oito meses de armazenamento mais sete dias de exposição a 20°C. A maçã 'Galaxy' apresentou menor porcentagem de podridões e polpa farinácea e maior firmeza de polpa em relação à 'Royal Gala', não apresentando interação nestes parâmetros com as condições de armazenamento. A 'Galaxy' apresentou a menor porcentagem de frutos com degenerescência senescente e maior acidez titulável quando comparada com a 'Royal Gala', ocorrendo interação destes parâmetros com as condições de armazenamento. A melhor condição de armazenamento para a cultivar 'Royal Gala' foi de 1,0kPa O2 + 2,5kPa CO2 e para a 'Galaxy' foi de 0,8 a 1,0kPa O2 e 2,5kPa CO2, porém a 'Galaxy' pode ser armazenada por um período maior, pois, apresentou potencial de armazenamento superior a 'Royal Gala'.The aim of this research was to evaluate the efficiency of controlled atmosphere conditions in the conservation of 'Royal Gala' and 'Galaxy' apples. The experimental design was completely randomized, with four replicates and the experimental unit composed by 25 fruits. Treatments were originated from the combination of two cultivars (Royal Gala and Galaxy and seven storage conditions, that were: [1] Cold storage (CS; [2

  19. Scientific discussion | Unifying physics and technology in light of Maxwell's equations | Royal Society, London | 16-17 November

    CERN Multimedia

    2015-01-01

    Discussion meeting organised by Professor Anatoly Zayats, Professor John Ellis and Professor Roy Pike.   16-17 November 2015 at The Royal Society 6-9 Carlton House Terrace, London Event details The unification of electric and magnetic fields about 150 years ago in what is now known as electromagnetic theory expressed in Maxwell's Equations has enabled virtually all modern electrical, electronic, radio and photonic technologies. What new scientific breakthroughs and applications will unification with the other fields provide? This meeting brings together high-energy, optical, quantum and solid-state physicists to discuss recent developments enabled by Maxwell's Equations and will try to predict future innovations. Attending this event This event is intended for researchers in relevant fields and is free to attend. There are a limited number of places and registration is essential. For more information, visit the Royal Society event website.

  20. Antigone a Port-Royal: obbedienza monastica e autonomia femminile in un’abbazia di Antico Regime

    Directory of Open Access Journals (Sweden)

    Silvana Bartoli

    2006-11-01

    Full Text Available Can a superior command to the conscience? Set inside a female religious tradition which for centuries answered in an affirmative way to this question, the nuns of Port Royal became rebels “proud as demons”, when they decided to say no to a document that required from them blind obedience. The History of Port Royal is indeed a history of a rebellion. The “day of the judas” and the denial of the Formulary are just the tip of the iceberg: the responsible consensus given by the nuns to the Benedettinian rules implies in itself the opposition to the rules of power. The model of an obedient nun is swept away by the obedience itself. Is it possible to apply Rossana Rossanda’s question «why disobedience is woman» to a monastery of the ancient regime?

  1. Thomas Birch's 'Weekly Letter' (1741-66): correspondence and history in the mid-eighteenth-century Royal Society.

    Science.gov (United States)

    Ellis, Markman

    2014-09-20

    Thomas Birch (1705-66), Secretary of the Royal Society from 1752 to 1765, and Philip Yorke, second Earl of Hardwicke (1720-90), wrote a 'Weekly Letter' from 1741 to 1766, an unpublished correspondence of 680 letters now housed in the British Library (Additional Mss 35396-400). The article examines the dimensions and purposes of this correspondence, an important conduit of information for the influential coterie of the 'Hardwicke circle' gathered around Yorke in the Royal Society. It explores the writers' self-conception of the correspondence, which was expressed in deliberately archaic categories of seventeenth-century news exchange, such as the newsletter, aviso and a-la-main. It shows how the letter writers negotiated their difference in status through the discourse of friendship, and concludes that the 'Weekly Letter' constituted for the correspondents a form of private knowledge, restricted in circulation to their discrete group, and as such unlike the open and networked model of Enlightenment science.

  2. The last Viking King: a royal maternity case solved by ancient DNA analysis.

    Science.gov (United States)

    Dissing, Jørgen; Binladen, Jonas; Hansen, Anders; Sejrsen, Birgitte; Willerslev, Eske; Lynnerup, Niels

    2007-02-14

    The last of the Danish Viking Kings, Sven Estridsen, died in a.d. 1074 and is entombed in Roskilde Cathedral with other Danish kings and queens. Sven's mother, Estrid, is entombed in a pillar across the chancel. However, while there is no reasonable doubt about the identity of Sven, there have been doubts among historians whether the woman entombed was indeed Estrid. To shed light on this problem, we have extracted and analysed mitochondrial DNA (mtDNA) from pulp of teeth from each of the two royals. Four overlapping DNA-fragments covering about 400bp of hypervariable region 1 (HVR-1) of the D-loop were PCR amplified, cloned and a number of clones with each segment were sequenced. Also a segment containing the H/non-H specific nucleotide 7028 was sequenced. Consensus sequences were determined and D-loop results were replicated in an independent laboratory. This allowed the assignment of King Sven Estridsen to haplogroup H; Estrid's sequence differed from that of Sven at two positions in HVR-1, 16093T-->C and 16304T-->C, indicating that she belongs to subgroup H5a. Given the maternal inheritance of mtDNA, offspring will have the same mtDNA sequence as their mother with the exception of rare cases where the sequence has been altered by a germ line mutation. Therefore, the observation of two sequence differences makes it highly unlikely that the entombed woman was the mother of Sven. In addition, physical examination of the skeleton and the teeth strongly indicated that this woman was much younger (approximately 35 years) at the time of death than the 70 years history records tell. Although the entombed woman cannot be the Estrid, she may well be one of Sven's two daughters-in-law who were also called Estrid and who both became queens.

  3. Characterisation of microRNAs from apple (Malus domestica 'Royal Gala') vascular tissue and phloem sap.

    Science.gov (United States)

    Varkonyi-Gasic, Erika; Gould, Nick; Sandanayaka, Manoharie; Sutherland, Paul; MacDiarmid, Robin M

    2010-08-04

    Plant microRNAs (miRNAs) are a class of small, non-coding RNAs that play an important role in development and environmental responses. Hundreds of plant miRNAs have been identified to date, mainly from the model species for which there are available genome sequences. The current challenge is to characterise miRNAs from plant species with agricultural and horticultural importance, to aid our understanding of important regulatory mechanisms in crop species and enable improvement of crops and rootstocks. Based on the knowledge that many miRNAs occur in large gene families and are highly conserved among distantly related species, we analysed expression of twenty-one miRNA sequences in different tissues of apple (Malus x domestica 'Royal Gala'). We identified eighteen sequences that are expressed in at least one of the tissues tested. Some, but not all, miRNAs expressed in apple tissues including the phloem tissue were also detected in the phloem sap sample derived from the stylets of woolly apple aphids. Most of the miRNAs detected in apple phloem sap were also abundant in the phloem sap of herbaceous species. Potential targets for apple miRNAs were identified that encode putative proteins shown to be targets of corresponding miRNAs in a number of plant species. Expression patterns of potential targets were analysed and correlated with expression of corresponding miRNAs. This study validated tissue-specific expression of apple miRNAs that target genes responsible for plant growth, development, and stress response. A subset of characterised miRNAs was also present in the apple phloem translocation stream. A comparative analysis of phloem miRNAs in herbaceous species and woody perennials will aid our understanding of non-cell autonomous roles of miRNAs in plants.

  4. The Society for Radiological Protection: incorporated by Royal Charter. How it was achieved

    International Nuclear Information System (INIS)

    Hunt, John; Scott, John

    2008-01-01

    The Society for Radiological Protection (the Society) began to consider the potential for incorporation by Royal Charter, an important goal for many professional bodies in the UK, in the mid-1980s. Impetus grew during the 1990s; contributing to this in 1998 was the Society's new status as direct UK IRPA associate. In 2002, to emphasise that the Society is active over all sectors of radiation protection, sectorial committees were established, dealing with professional interests in the component sectors. Application for a Charter begins with a Memorandum to Her Majesty the Queen's Privy Council Office (PCO) with details of the Society, its achievements and why grant of a Charter would be in the public interest. The Society prepared a Memorandum and submitted it to the PCO in 2003. In 2004, the application was declined for several reasons, which were then considered. Contacts in Government Departments were briefed on the Society's activities. The Society and the Institute of Radiation Protection (IRP) had been considering amalgamation, and in 2005 the annual general meetings of the Society and IRP agreed to proposals for a merger. A new Memorandum was submitted to the PCO in 2005, and early in 2006 it was accepted. It was then necessary to draft a Charter and a Petition to HM the Queen in Council. One of the opportunities incorporated in the Charter is the provision to award the title 'Chartered Radiation Protection Professional' with the post-nominal letters 'CRadP' to suitable members. Draft documents were presented to the Society's 2007 annual general meeting, and passed through Society's governance procedures. Public consultation by the PCO took place during summer 2007. On 10 October 2007 an order granting a Charter of Incorporation was approved at the Privy Council held by the Queen. The Charter was presented to the Society on 11 December 2007. (author)

  5. Visitors' perception of thermal comfort during extreme heat events at the Royal Botanic Garden Melbourne

    Science.gov (United States)

    Lam, Cho Kwong Charlie; Loughnan, Margaret; Tapper, Nigel

    2018-01-01

    Outdoor thermal comfort studies have mainly examined the perception of local residents, and there has been little work on how those conditions are perceived differently by tourists, especially tourists of diverse origins. This issue is important because it will improve the application of thermal indices in predicting the thermal perception of tourists. This study aims to compare the differences in thermal perception and preferences between local and overseas visitors to the Royal Botanic Garden (RBG) in Melbourne during summer. An 8-day survey was conducted in February 2014 at four sites in the garden ( n = 2198), including 2 days with maximum temperature exceeding 40 °C. The survey results were compared with data from four weather stations adjacent to the survey locations. One survey location, `Fern Gully', has a misting system and visitors perceived the Fern Gully to be cooler than other survey locations. As the apparent temperature exceeded 32.4 °C, visitors perceived the environment as being `warm' or `hot'. At `hot' conditions, 36.8 % of European visitors voted for no change to the thermal conditions, which is considerably higher than the response from Australian visitors (12.2 %) and Chinese visitors (7.5 %). Study results suggest that overseas tourists have different comfort perception and preferences compared to local Australians in hot weather based at least in part on expectations. Understanding the differences in visitors' thermal perception is important to improve the garden design. It can also lead to better tour planning and marketing to potential visitors from different countries.

  6. Fatty acids isolated from royal jelly modulate dendritic cell-mediated immune response in vitro.

    Science.gov (United States)

    Vucevic, Dragana; Melliou, Eleni; Vasilijic, Sasa; Gasic, Sonja; Ivanovski, Petar; Chinou, Ioanna; Colic, Miodrag

    2007-09-01

    Royal jelly (RJ), especially its protein components, has been shown to possess immunomodulatory activity. However, almost nothing is known about the influence of RJ fatty acids on the immune system. In this work we studied the effect of 10-hydroxy-2-decanoic acid (10-HDA) and 3,10-dihydroxy-decanoic acid (3,10-DDA), isolated from RJ, on the immune response using a model of rat dendritic cell (DC)-T-cell cocultures. Both fatty acids, at higher concentrations, inhibited the proliferation of allogeneic T cells. The effect of 10-HDA was stronger and was followed by a decrease in interleukin-2 (IL-2) production and down-regulation of IL-2 receptor expression. Spleen DC, cultivated with 10 microg/ml of fatty acids down-regulated the expression of CD86 and the production of IL-12, but up-regulated the production of IL-10. In contrast, DC, pretreated with 100 microg/ml of 3,10-DDA, up-regulated the expression of CD86 and augmented the proliferation of allogeneic T cells. The highest dose (200 microg/ml) of both fatty acids which was non-apoptotic for both T cells and DC, down-regulated the expression of MHC class II and CD86, decreased the production of IL-12 and made these DC less allostimulatory. The immunosuppressive activity of 3,10-DDA was also confirmed in vivo, using a model of Keyhole lymphet hemocyanine immunization of rats. In conclusion, our results showed the immunomodulatory activity of RJ fatty acids and suggest that DC are a significant target of their action.

  7. Royal Jelly Modulates Oxidative Stress and Apoptosis in Liver and Kidneys of Rats Treated with Cisplatin

    Directory of Open Access Journals (Sweden)

    Ali Karadeniz

    2011-01-01

    Full Text Available Cisplatin (CDDP is one of the most active cytotoxic agents in the treatment of cancer and has adverse side effects such as nephrotoxicity and hepatotoxicity. The present study was designed to determine the effects of royal jelly (RJ against oxidative stress caused by CDDP injury of the kidneys and liver, by measuring tissue biochemical and antioxidant parameters and investigating apoptosis immunohistochemically. Twenty-four Sprague Dawley rats were divided into four groups, group C: control group received 0.9% saline; group CDDP: injected i.p. with cisplatin (CDDP, 7 mg kg-1 body weight i.p., single dose; group RJ: treated for 15 consecutive days by gavage with RJ (300 mg/kg/day; group RJ + CDDP: treated by gavage with RJ 15 days following a single injection of CDDP. Malondialdehyde (MDA and glutathione (GSH levels, glutathione S-transferase (GST, glutathione peroxidase (GSH-Px, and superoxide dismutase (SOD activities were determined in liver and kidney homogenates, and the liver and kidney were also histologically examined. RJ elicited a significant protective effect towards liver and kidney by decreasing the level of lipid peroxidation (MDA, elevating the level of GSH, and increasing the activities of GST, GSH-Px, and SOD. In the immunohistochemical examinations were observed significantly enhanced apoptotic cell numbers and degenerative changes by cisplatin, but these histological changes were lower in the liver and kidney tissues of RJ + CDDP group. Besides, treatment with RJ lead to an increase in antiapoptotic activity hepatocytes and tubular epithelium. In conclusion, RJ may be used in combination with cisplatin in chemotherapy to improve cisplatin-induced oxidative stress parameters and apoptotic activity.

  8. Spectral domain optical coherence tomography imaging of spectacular ecdysis in the royal python (Python regius).

    Science.gov (United States)

    Tusler, Charlotte A; Maggs, David J; Kass, Philip H; Paul-Murphy, Joanne R; Schwab, Ivan R; Murphy, Christopher J

    2015-01-01

    To describe using spectral domain optical coherence tomography (SD-OCT), digital slit-lamp biomicroscopy, and external photography, changes in the ophidian cuticle, spectacle, and cornea during ecdysis. Four normal royal pythons (Python regius). Snakes were assessed once daily throughout a complete shed cycle using nasal, axial, and temporal SD-OCT images, digital slit-lamp biomicroscopy, and external photography. Spectral domain optical coherence tomography (SD-OCT) images reliably showed the spectacular cuticle and stroma, subcuticular space (SCS), cornea, anterior chamber, iris, and Schlemm's canal. When visible, the subspectacular space (SSS) was more distended peripherally than axially. Ocular surface changes throughout ecdysis were relatively conserved among snakes at all three regions imaged. From baseline (7 days following completion of a full cycle), the spectacle gradually thickened before separating into superficial cuticular and deep, hyper-reflective stromal components, thereby creating the SCS. During spectacular separation, the stroma regained original reflectivity, and multiple hyper-reflective foci (likely fragments from the cuticular-stromal interface) were noted within the SCS. The cornea was relatively unchanged in character or thickness throughout all stages of ecdysis. Slit-lamp images did not permit observation of these changes. Spectral domain optical coherence tomography (SD-OCT) provided excellent high-resolution images of the snake anterior segment, and especially the cuticle, spectacle, and cornea of manually restrained normal snakes at all stages of ecdysis and warrants investigation in snakes with anterior segment disease. The peripheral spectacle may be the preferred entry point for diagnostic or therapeutic injections into the SSS and for initiating spectacular surgery. © 2014 American College of Veterinary Ophthalmologists.

  9. Optimized determination method for trans-10-hydroxy-2-decenoic acid content in royal jelly by high-performance liquid chromatography with an internal standard.

    Science.gov (United States)

    Zhou, Jinhui; Xue, Xiaofeng; Li, Yi; Zhang, Jinzhen; Zhao, Jing

    2007-01-01

    An optimized reversed-phase high-performance liquid chromatography method was developed to detect the trans-10-hydroxy-2-decenoic acid (10-HDA) content in royal jelly cream and lyophilized powder. The sample was extracted using absolute ethanol. Chromatographic separation of 10-HDA and methyl 4-hydroxybenzoate as the internal standard was performed on a Nova-pak C18 column. The average recoveries were 95.0-99.2% (n = 5) with relative standard deviation (RSD) values of 1.3-2.1% for royal jelly cream and 98.0-100.0% (n = 5) with RSD values of 1.6-3.0% for lyophilized powder, respectively. The limits of detection and quantitation were 0.5 and 1.5 mg/kg, respectively, for both royal jelly cream and lyophilized powder. The method was validated for the determination of practical royal jelly products. The concentration of 10-HDA ranged from 1.26 to 2.21% for pure royal jelly cream samples and 3.01 to 6.19% for royal jelly lyophilized powder samples. For 30 royal jelly products, the 10-HDA content varied from not detectable to 0.98%.

  10. The epidemiology of Scottish trauma: A comparison of pre-hospital and in-hospital deaths, 2000 to 2011.

    Science.gov (United States)

    Morrison, Jonathan J; Yapp, Liam Z; Beattie, Anne; Devlin, Eimar; Samarage, Milan; McCaffer, Craig; Jansen, Jan O

    2016-02-01

    To characterise the temporal trends and urban-rural distribution of fatal injuries in Scotland through the analysis of mortality data collected by the National Records of Scotland. The prospectively collected NRS database was queried using ICD-10 codes for all Scottish trauma deaths during the period 2000 to 2011. Patients were divided into pre-hospital and in-hospital groups depending on the location of death. Incidence was plotted against time and linear regression was used to identify temporal trends. A total of 13,100 deaths were analysed. There were 4755 (36.3%) patients in the pre-hospital group with a median age (IQR) of 42 (28-58) years. The predominant cause of pre-hospital death related to vehicular injury (27.8%), which had a decreasing trend over the study period (p = 0.004). In-hospital, patients had a median age of 80 (58-88) years and the majority (67.0%) of deaths occurred following a fall on the level. This trend was shown to increase over the decade of study (p = 0.020). In addition, the incidence of urban incidents remained static, but the rate of rural fatal trauma decreased (p Scottish trauma patients die prior to hospital admission and the predominant mechanism of injury is due to road traffic accidents. This contrasts with in-hospital deaths, which are mainly observed in elderly patients following a fall from standing height. Further research is required to determine the preventability of fatal traumatic injury in Scotland. Copyright © 2015 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

  11. Why are some evidence-based care recommendations in chronic obstructive pulmonary disease better implemented than others? Perspectives of medical practitioners

    Directory of Open Access Journals (Sweden)

    Johnston KN

    2011-12-01

    Full Text Available Kylie N Johnston1, Mary Young2, Karen A Grimmer-Somers1, Ral Antic3, Peter A Frith41International Centre for Allied Health Evidence, University of South Australia, Adelaide, South Australia, Australia; 2Transitional and Community Services, Royal Adelaide Hospital, Adelaide, South Australia, Australia; 3Department of Thoracic Medicine, Royal Adelaide Hospital, Adelaide, South Australia, Australia; 4Respiratory, Allergy and Sleep Services, Repatriation General Hospital and Flinders University Adelaide, South Australia, AustraliaBackground: Clinical guidelines for management of patients with chronic obstructive pulmonary disease (COPD include recommendations based on high levels of evidence, but gaps exist in their implementation. The aim of this study was to examine the perspectives of medical practitioners regarding implementation of six high-evidence recommendations for the management of people with COPD.Methods: Semi-structured interviews were conducted with medical practitioners involved with care of COPD patients in hospital and general practice. Interviews sought medical practitioners' experience regarding implementation of smoking cessation, influenza vaccination, pulmonary rehabilitation, guideline-based medications, long-term oxygen therapy for hypoxemia and plan and advice for future exacerbations. Interviews were audiotaped, transcribed verbatim and analyzed using content analysis.Results: Nine hospital-based medical practitioners and seven general practitioners participated. Four major categories were identified which impacted on implementation of the target recommendations in the care of patients with COPD: (1 role clarity of the medical practitioner; (2 persuasive communication with the patient; (3 complexity of behavioral change required; (4 awareness and support available at multiple levels. For some recommendations, strength in all four categories provided significant enablers supporting implementation. However, with regard to

  12. Age, growth, and maturity of round whitefish of the Apostle Islands and Isle Royale Regions, Lake Superior

    Science.gov (United States)

    Bailey, Merryll M.

    1963-01-01

    The round whitefish has been of some commercial importance in the upper Great Lakes but production in Lake Superior has generally been small; the United States average was 26,600 pounds for 1929-59. This study is based on 1,173 fish collected in the Apostle Islands in 1958-60 and 103 collected at Isle Royale in 1958 and 1960. The average age of 6.0 years at Isle Royale was concluded to be significantly higher than the mean of 4.2 years in the Apostle Islands. The body-scale relation is a straight line with an intercept of 1.1 inches on the length axis. Weight of Apostle Islands round whitefish captured in several months increased as the 3.22 power of the length. Growth in length was relatively slow; nearly or fully 7 years were required to reach an acceptable commercial length of 14 inches in both the Apostle Islands and at Isle Royale. The calculated weights at the end of the seventh year were 12.6 ounces in the Apostle Islands and 13.8 ounces at Isle Royale. Minimum length at maturity of male round whitefish (7.0-7.4 inches) was less than that of females (8.5-8.9 inches). At age-group II, 11.1 percent of male round whitefish, but only 1.5 percent of the females were mature. All males were mature as age-group V and all females as age-group VI. Males dominated the younger age groups but females were more numerous in the older ones. Estimates of the number of eggs in 37 round whitefish ovaries yielded an average of 5,330 eggs for fish 10.5-17.4 inches long.

  13. A royal visit : King Harald V and Queen Sonja of Norway made a trip to CERN on Tuesday 4 April

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    CERN Director-General Robert Aymar welcomed the royal party, which included the Norwegian Minister of Foreign Affairs, Jonas Gahr Støre, and provided an overview of CERN's history and current and future research. ATLAS deputy spokesperson Steinar Stapnes then quickly explained the concept and inner workings of the LHC, some LHC physics goals and ATLAS, which is one of the main experiments receiving Norwegian contributions

  14. Efficacy of Royal Jelly in Modulating Radiation-Induced Liver Damage in Rats Subjected to Low Level of Gamma Radiation

    International Nuclear Information System (INIS)

    Ibrahim, N.K.

    2010-01-01

    Royal Jelly (RJ) is bee product, rich in proteins, vitamins, enzymes, minerals, hormones (trace elements of testosterone), lipids, glucides, niacin, pantothenic acid, biotin, inositol and folic acid, which may be beneficial in neutralizing the free oxygen radicals. The present study was carried out evaluate the radio-protective effect of Royal Jelly exposure of male Swiss albino rats to 1 Gy for 5 times day post day. Royal jelly was supplemented by gavage to rats at a dose of 150 mg/ kg body wt/ day for successive 10 days through exposure to gamma radiation 1 Gy x 5 time day post day. The dose of royal jelly is equivalent to daily human nutritional supplementation quantity. The result revealed that whole body gamma-irradiation of rats produced significant decrease in plasma total protein, albumin and globulin contents and significant increase in plasma alanine transaminase (ALT) and aspartate transaminase (AST) activity. However, plasma testosterone significantly decrease and follicle-stimulating hormone (FSH) and luteinising hormone (LH) significantly increased. Cholesterol (TC), triacyleglycerol (TAC), superoxide dismutase (SOD) and glutathione per oxidise (GSHPx) decreased whereas, malondialdehde (MDA) increased. Oral administration of the RJ exerted a noticeable amelioration of the radiation induced hormonal and biochemical changes according to the results of the present study. It could be concluded that RJ possess anti-oxidative potential that may protect the liver against ?-radiation induced acute oxidative toxicity. This protective effect might be mediated, at least in part, by the limitation of culprit free radicals and the amelioration of oxidative stress and also due to the synergistic relationship between the natural components found in RJ

  15. Improving the beam quality of the neutron radiography facility using the SLOWPOKE-2 at the Royal Military College of Canada

    International Nuclear Information System (INIS)

    Lewis, W.J.; Bennett, L.G.I.; Teshima, P.

    1996-01-01

    At the SLOWPOKE-2 Facility at the Royal Military College of Canada, a neutron radiography facility has been designed and installed, and the beam quality has been improved by performing a series of radiographs using American standard for testing and materials (ASTM) E 545 indicators. Other means of determining the progress such as bubble detectors and activation foils were used. Modifications to the nosepiece of the beam tube including shielding and linings for fast neutron and gamma radiation were made. (orig.)

  16. PARTIAL PURIFICATION AND IMMUNE-BIOCHEMICAL CHARACTERIZATION OF ROYAL BENGAL TIGER ( PANTHERA TIGRIS TIGRIS SERUM IMMUNOGLOBULIN G

    Directory of Open Access Journals (Sweden)

    Ekantika Mandal

    2013-12-01

    Full Text Available In the present study Immunoglobulin G was purified from serum of Royal Bengal Tiger by gel filtration chromatography on Sephacryl S-200. SDS-PAGE analysis showed the molecular weight of purified tiger IgG was 170.52 kDa. The purified Immunoglobulin has been found to be immunereactive by DID test and Western Blot analysis when treated against hyperimmune sera which was raised in rabbit.

  17. Creation of Malaysia’s Royal Belum State Park: A Case Study of Conservation in a Developing Country

    OpenAIRE

    Schwabe, KA; Carson, RT; DeShazo, JR; Potts, MD; Reese, AN; Vincent, JR

    2015-01-01

    © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav. The incentives for resource extraction and development make the conservation of biodiversity challenging within tropical forestlands. The 2007 establishment of the Royal Belum State Park in the Malaysian state of Perak offers lessons for creating protected areas in tropical countries where subnational governments are major forestland owners. This article elucidates the social and political forces that influe...

  18. The multi-role nature of the SLOWPOKE-2 facility at the Royal Military College of Canada

    International Nuclear Information System (INIS)

    Bennett, L.G.I.; Beeley, P.A.

    1994-01-01

    After up to a decade of successful operation of seven SLOWPOKE-2 reactors within Canada and in Jamaica, an eighth SLOWPOKE-2 research reactor was installed at the Royal Military College of Canada in 1985. Its open pool was one factor that allowed the authors to develop a variety of research capabilities beyond those being established for NAA. A description of the research projects to date will serve to indicate the diversity of this facility. (author) 14 refs.; 4 figs.; 1 tab

  19. The response of the Government of Ontario to the final report of the Royal Commission on Electric Power Planning

    International Nuclear Information System (INIS)

    1981-05-01

    In March 1980, after nearly five years of hearings and research, the Ontario Royal Commission on Electric Power Planning submitted the first volume of its final report. The remaining eight volumes were submitted in April 1980. The Commission made 88 recommendations on technical, operational, and policy issues. The present document sets out the Ontario government's response to the recommendations. The government accepts and is implementing 77 recommendations. Four recommendations require further study, and six have been rejected

  20. Report of the Hydrographic Service Royal Australian Navy for the Year Ended 30th June 1983, Issue Number 19.

    Science.gov (United States)

    1983-01-01

    eastwards of MORESBY’s 1981 survey. The ship suffered considerable problems in establishing her ARGO stations on this barren and inhospitable coast...on 6 months exchange whilst an RFMF officer pined experience in Australia. A CPOSR has continued the loan service arrang-ments in support of the...training in hydrographic surveying is undertaken at the Royal Navy’s Hydrographic School in Plymouth . It is expected that an average of four officers will

  1. From the Royal Castle to school. King Stanisław August’s legacy and the Volhynian Gymnasium collections

    Directory of Open Access Journals (Sweden)

    Katarzyna Buczek

    2017-01-01

    Full Text Available The library and the cabinet collections of King of Poland Stanisław August Poniatowski reflect the trends of the Enlightement as well as the monarch’s interests. Their acquisition by one of the most important Polish schools, the Volhynian Gymnasium in Kremenets, saved them from dismemberment and gave rise to school collections. The acquisition was possible owing to history (the Partition of Poland, and the emergence of the Vilna Educational District and a unique man – Tadeusz Czacki. The collections at the Volhynian Gymnasium in Kremenets was open to the public on a daily basis. In this way, the Polish King’s Stanisław August wish to have the collection available for masses came true, after his death regrettably. School collections were very valuable. Having originated from the royal collection of the last Polish King, they became a reminiscence of the national potential of a country that disappeared from the map of Europe in 1795. This article is a part of a future book and an attempt of documenting the transition of respective collections from the royal residence in Warsaw to Kremenets. The analysis of Polish, Lithuanian and Ukrainian archives enables to reconstruct the history of the royal collections and to show their quality and didactic utility.

  2. MRI assessment program

    International Nuclear Information System (INIS)

    1988-05-01

    Usage, cost and efficacy data from the MRI Assessment Program to 30 March 1988 is presented, as a continuation of an earlier analysis. Analysis has been performed on data from 8565 examinations relating to 7997 patients at 4 hospitals. MRI was used mainly for examination of the head and spine. Some details of the follow up studies being conducted on selected patients and disease categories are given. A consensus statement is included which summaries the view of the Technical Committee on the potential applications of MRI in Australia. The MRI unit quench incident at Royal Adelaide Hospital is described. Refs., 10 figs., tabs

  3. Violence toward health workers in Bahrain Defense Force Royal Medical Services’ emergency department

    Science.gov (United States)

    Rafeea, Faisal; Al Ansari, Ahmed; Abbas, Ehab M; Elmusharaf, Khalifa; Abu Zeid, Mohamed S

    2017-01-01

    Background Employees working in emergency departments (EDs) in hospital settings are disproportionately affected by workplace violence as compared to those working in other departments. Such violence results in minor or major injury to these workers. In other cases, it leads to physical disability, reduced job performance, and eventually a nonconducive working environment for these workers. Materials and methods A cross-sectional exploratory questionnaire was used to collect data used for the examination of the incidents of violence in the workplace. This study was carried out at the ED of the Bahrain Defense Force (BDF) Hospital. Participants for the study were drawn from nurses, support staff, and emergency physicians. Both male and female workers were surveyed. Results The study included responses from 100 staff in the ED of the BDF Hospital in Bahrain (doctors, nurses, and support personnel). The most experienced type of violence in the workers in the past 12 months in this study was verbal abuse, which was experienced by 78% of the participants, which was followed by physical abuse (11%) and then sexual abuse (3%). Many cases of violence against ED workers occurred during night shifts (53%), while physical abuse was reported to occur during all the shifts; 40% of the staff in the ED of the hospital were not aware of the policies against workplace violence, and 26% of the staff considered leaving their jobs at the hospital. Conclusion This study reported multiple findings on the number of workplace violence incidents, as well as the characteristics and factors associated with violence exposure in ED staff in Bahrain. The results clearly demonstrate the importance of addressing the issue of workplace violence in EDs in Bahrain and can be used to demonstrate the strong need for interventions. PMID:29184452

  4. Direct hospital costs of total laparoscopic hysterectomy compared with fast-track open hysterectomy at a tertiary hospital: a retrospective case-controlled study.

    Science.gov (United States)

    Rhou, Yoon J J; Pather, Selvan; Loadsman, John A; Campbell, Neil; Philp, Shannon; Carter, Jonathan

    2015-12-01

    To assess the direct intraoperative and postoperative costs in women undergoing total laparoscopic hysterectomy and fast-track open hysterectomy. A retrospective review of the direct hospital-related costs in a matched cohort of women undergoing total laparoscopic hysterectomy (TLH) and fast-track open hysterectomy (FTOH) at a tertiary hospital. All costs were calculated, including the cost of advanced high-energy laparoscopic devices. The effect of the learning curve on cost in laparoscopic hysterectomy was also assessed, as was the hospital case-weighted cost, which was compared with the actual cost. Fifty women were included in each arm of the study. TLH had a higher intraoperative cost, but a lower postoperative cost than FTOH (AUD$3877 vs AUD$2776 P funding model in our hospital is inaccurate when compared to directly calculated hospital costs. © 2013 The Authors ANZJOG © 2013 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

  5. Adapting the botanical landscape of Melbourne Gardens (Royal Botanic Gardens Victoria in response to climate change

    Directory of Open Access Journals (Sweden)

    Timothy J. Entwisle

    2017-12-01

    Full Text Available Botanic gardens around the world maintain collections of living plants for science, conservation, education, beauty and more. These collections change over time – in scope and content – but the predicted impacts of climate change will require a more strategic approach to the succession of plant species and their landscapes. Royal Botanic Gardens Victoria has recently published a ‘Landscape Succession Strategy’ for its Melbourne Gardens, a spectacular botanical landscape established in 1846. The strategy recognizes that with 1.6 million visitors each year, responsibility for a heritage-listed landscape and the need to care for a collection of 8500 plant species of conservation and scientific importance, planting and planning must take into account anticipated changes to rainfall and temperature. The trees we plant today must be suitable for the climate of the twenty-second century. Specifically, the Strategy sets out the steps needed over the next twenty years to transition the botanic garden to one resilient to the climate modelled for 2090. The document includes a range of practical measures and achievable (and at times somewhat aspirational targets. Climate analogues will be used to identify places in Australia and elsewhere with conditions today similar to those predicted for Melbourne in 2090, to help select new species for the collection. Modelling of the natural and cultivated distribution of species will be used to help select suitable growth forms to replace existing species of high value or interest. Improved understanding of temperature gradients within the botanic garden, water holding capacity of soils and plant water use behaviour is already resulting in better targeted planting and irrigation. The goal is to retain a similar diversity of species but transition the collection so that by 2036 at least 75% of the species are suitable for the climate in 2090. Over the next few years we hope to provide 100% of irrigation water

  6. Evidence given by the National Radiological Protection Board to the Royal Commission on Environmental Pollution

    International Nuclear Information System (INIS)

    1976-09-01

    In March of 1976 The Royal Commission on Environmental Pollution informed the Board that they had decided to enquire into the organisation for radiological safety in this country, with particular regard to the environmental hazards from radioactivity that might arise from the increasing use of nuclear energy for the generation of electrical power. The Board was invited to submit evidence on any aspects with which it was concerned and, in particular, on its powers and responsibilities and relationships with other bodies; the Board was also asked to discuss the assessment of radiation hazards and the application in practice of the recommendations of the International Commission on Radiological Protection. This is the Board's response. The constitution, functions and responsibilities of the Board are discussed in Chapter 1 as is the involvement of its staff in national and international affairs in the field of radiological protection. Chapter consists of a short statement of the various sources of radiation to which the people of the UK are exposed. The Board does not claim any special experience or expertise in one of the matters referred to in the third area of concern, namely, the criteria used for the siting of nuclear power stations. But in the related field of assessing the environmental consequences of reactor accidents, the Board has been actively involved with the Medical Research Council in their latest review of Emergency Reference Levels - a report on which is shortly to be published. This subject is referred to in Chapter 3 which deals with the methods by which the basic recommendations of the International Commission on Radiological Protection are translated into values that can be applied to particular forms of practice. Chapter 4 discusses the current position of gaseous, liquid and solid wastes arising from nuclear power cycles. It also briefly discusses the way in which this position may change in future and touches on the problems of decommissioning

  7. Royal Engineer Geographic Technicians: Exploring their attitudes to education and training

    Science.gov (United States)

    Knight, John Anthony

    A creative approach is presented for understanding the attitudes of Royal Engineer (RE) Geographic Technicians (Geo Techs) to training and education. Through a grounded theory methodology, participants' experiences of learning and teaching are explored. These provide a greater awareness and perception of attitudes than have emerged through more established, formal methods of evaluating the effectiveness of training. Recent developments in technology, doctrine, requirements and operations have brought about significant changes to the range and complexity of subjects taught in the field of Geospatial Intelligence (GEOINT). This in turn has increased the challenges to RE staff and students, many of whom find themselves instructing on or undertaking demanding degree level courses without the requisite formal qualifications. Grounded theory, based on guidelines rather than rigid rules, is adopted to provide a study of RE Geographic Technicians' learning experiences from the perspective of those who live it and for an interpretive understanding of their meanings to emerge. The policies, culture and social processes in which the RE Geo training takes place are explored to appreciate the influence of the training environment on learning. Data obtained through focus groups held with students and instructors, and through in-depth interviews with individuals who hold key roles associated with the course, recognises the relativism of multiple social realities in developing a rich source of knowledge on attitudes to learning. The collection, synthesis and analysis of data led to the emergence of core categories: context, commitment, expectations, motivation, qualifications, relevance and respect. Through their engagement the research participants' awareness, in particular of instructors, of Geographic Technicians' attitudes to training and education has been raised. Using the theoretical framework of communities of practice, the challenges and effectiveness of the RSMS as a

  8. Effects of royal jelly on genotoxicity and nephrotoxicity induced by valproic acid in albino mice

    Directory of Open Access Journals (Sweden)

    Sanaa R. Galaly

    2014-03-01

    Full Text Available Epilepsy is one of the most common neurological diseases affecting at least 50 million people worldwide. Valproic acid (VPA is a widely used antiepileptic medication for both generalized and partial seizures of epilepsy. The objective of the study was to investigate the anti-mutagenic and anti-histopathologic effects of royal jelly (RJ on VPA-induced genotoxicity and nephrotoxicity in male albino mice (Mus musculus. 80 Mice were used for 21 days; they were divided into eight groups, (G1 served as normal control group, G2 received VPA (100 mg/kg and (G3–G5 received RJ at doses 50, 100 and 200 mg/kg respectively. While (G6–G8 were administrated RJ simultaneously with VPA. In RJ treated mice at doses of 50 and 100 mg/kg, the kidney sections showed normal histological structure with non significant changes in chromosomal aberrations (CA and mitotic index (MI, while RJ at dose of 200 mg/kg showed mild inflammatory cells infiltration and hyperemic glomeruli but not highly significant changes in CA and MI. The cortex of VPA treated mice revealed congested glomeruli with inflammatory cells infiltration, and marked degeneration of almost structures of the glomeruli including some vacuoles in mesangial cells with dark mesangial substances on the ultrastructure level. Some proximal tubules showed degeneration of microvilli on the apical parts of some cells. Cells of the distal tubules attained obliterated lumen and vacuolated lining epithelium. The results also revealed that valproic acid induced a high frequency of CA in bone marrow cells of mice and MI was significantly decreased indicating bone marrow cytotoxicity. The treatment of mice with RJ at doses 50, 100 and 200 mg/kg for 21 days simultaneously with VPA resulted in abating the histological alterations in renal tissues with significant reduction in chromosomal aberrations, for doses of 50 and 100 mg/kg, and elevation in mitotic index (P < 0.05. RJ at doses 50 and 100 mg/kg appeared

  9. Microbial monitoring in treated stone at the Royal Chapel of Granada

    Science.gov (United States)

    Jroundi, Fadwa; Pinar, Guadalupe; González-Muñoz, Maria Theresa; Sterflinger, Katja

    2014-05-01

    Biomineralization processes have been applied in situ to protect and consolidate decayed ornamental stone of the Royal Chapel in Granada (Spain). In few years, this conservation treatment has gained worth attention as environmentally friendly methodology for protection and consolidation of limestone because of the compatibilities shown between the new calcium carbonate cement and the original stone substrate. Moreover, the success of this approach may be related to the diversity of the microbiota inhabiting the stone and activated upon the biotreatment application and throughout the time. González-Muñoz et al. (2008) proposed a nutritional solution that activate among the bacteria inhabiting the stone those with carbonatogenic activity. In this study, a long-term (one, two and three years) monitoring of the microbiota present on the treated and untreated stones was done using a molecular strategy, including total DNA extraction, PCR amplification of 16S rRNA sequences, construction of clone libraries and fingerprinting by DGGE (Denaturing Gradient Gel Electrophoresis) analysis. Sequencing of the 16S rDNA revealed the dominant occurrence of members of Actinobacteria (44.20%), Gamma-proteobacteria (30.24%) and Chloroflexi (25.56%) after one year of the biotreatment. Whereas after two years, members of Cyanobacteria (22.10%) appeared and three years after, the microbiota consisted of only Actinobacteria and Cyanobacteria with approximately the same percentage in comparison with the untreated stones, dominated exclusively by Actinobacteria (100%). Fungal diversity followed the same dynamic as bacterial diversity being Ascomicota the predominant order before treatment. After one year, members of Basidiomycota and Viridiplantae appeared on the stone while two years after, the Viridiplantae dominated with a percentage of 84.77%. Finally, three years after the treatment, fungi population started to stabilize again and Ascomicota predominated next to 16.67% of

  10. Lifespan-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegans.

    Directory of Open Access Journals (Sweden)

    Yoko Honda

    Full Text Available One of the most important challenges in the study of aging is to discover compounds with longevity-promoting activities and to unravel their underlying mechanisms. Royal jelly (RJ has been reported to possess diverse beneficial properties. Furthermore, protease-treated RJ (pRJ has additional pharmacological activities. Exactly how RJ and pRJ exert these effects and which of their components are responsible for these effects are largely unknown. The evolutionarily conserved mechanisms that control longevity have been indicated. The purpose of the present study was to determine whether RJ and its related substances exert a lifespan-extending function in the nematode Caenorhabditis elegans and to gain insights into the active agents in RJ and their mechanism of action.We found that both RJ and pRJ extended the lifespan of C. elegans. The lifespan-extending activity of pRJ was enhanced by Octadecyl-silica column chromatography (pRJ-Fraction 5. pRJ-Fr.5 increased the animals' lifespan in part by acting through the FOXO transcription factor DAF-16, the activation of which is known to promote longevity in C. elegans by reducing insulin/IGF-1 signaling (IIS. pRJ-Fr.5 reduced the expression of ins-9, one of the insulin-like peptide genes. Moreover, pRJ-Fr.5 and reduced IIS shared some common features in terms of their effects on gene expression, such as the up-regulation of dod-3 and the down-regulation of dod-19, dao-4 and fkb-4. 10-Hydroxy-2-decenoic acid (10-HDA, which was present at high concentrations in pRJ-Fr.5, increased lifespan independently of DAF-16 activity.These results demonstrate that RJ and its related substances extend lifespan in C. elegans, suggesting that RJ may contain longevity-promoting factors. Further analysis and characterization of the lifespan-extending agents in RJ and pRJ may broaden our understanding of the gene network involved in longevity regulation in diverse species and may lead to the development of nutraceutical

  11. Some radiation protection problems in a cancer hospital and associated research institute

    International Nuclear Information System (INIS)

    Trott, N.G.; Anderson, W.; Davis, R.P.; Carden, D.M.

    1980-01-01

    Experience gained at the Royal Marsden Hospital and Institute of Cancer Research has shown that with attention to the design of facilities and procedures and an active personnel monitoring policy, relatively large scale radiation commitments can proceed with individual whole body doses to staff being held well below 15 mSv/annum. In spite of detailed attention to control of radiation work, traumatic radiation incidents may still occur. (H.K.)

  12. Marshal of the Royal Air Force Sir John Cotesworth Slessor and the Anglo-American Air Power Alliance, 1940-1945

    National Research Council Canada - National Science Library

    Connolly, Corvin

    2001-01-01

    .... He played a remarkable and extensive role in building the Anglo-American air power partnership as an air planner on the Royal Air Force Staff, the British Chiefs of Staff, and the Combined Chiefs of Staff...

  13. STANDAR PERALATAN PASTRY AND BAKERY SECTION DI HOTEL GRAND ROYAL PANGHEGAR BANDUNG

    Directory of Open Access Journals (Sweden)

    Adhitya Ryandi

    2016-03-01

    Full Text Available Abstract - Pastry and bakery section is a section or division under the auspices  of  the   main  kitchen are responsible for handling various  events  such as hotel  weding, birthday  party, coffee break, breakfast,  lunch,  diner,  and others. The issue  will be examined how the  standard equipment  of the pastry  and bakery  section in  Hotel Grand Royal Panghegar Bandung. In terms of processing data, the authors use deskriptip analysis of  techniques of writing that tells something based on  experience  or empirical  data, which are compiled in the form of a report. Based on the observations that have been made by the author, the standard equipment of the pastry and bakery section has good and sufficient. But theem powerment  of the same  equipment  the machine is still less complete. The amount of  pastry and bakery  equipment section is adequately tailored to the capacity of event that uses the products of pastry and bakery. Pastry and bakery e quipment  conditions section is still good, but in terms of the cleanliness of the equipment is still less, so it will decrease the effectiveness of the work of the equipment. Based on data obtained by the author, the author concludes that the standard equipment is very important for the quality of the resulting product. But if  standard equipment owned less adequate, it could be addressed with mobiltas employees who have the skill and knowledge in the field of pastry and bakery.   Keyword: Pastry, Bakery, Equipment, Products Abstrak - Pastry and bakery section merupakan section atau divisi di bawah naungan main kitchen yang bertanggung jawab menangani berbagai event-event hotel seperti weding, birthday party, coffee break, breakfast, luch, diner,dan lain-lain. Masalah yang akan diteliti yaitu bagaimana standar peralatan pastry and bakery section di Hotel Grand Royal

  14. Effects of Propolis, Royal Jelly, Bee Pollen and Ronozyme Supplementation in Diets of Japanese Quails (Coturnix Coturnix Japonica) on Yolk Lipid Peroxidation

    OpenAIRE

    Yılmaz S; Tatli Seven P; Kaya E

    2017-01-01

    This study discovers the possible effect propolis, royal jelly, bee pollen and Ronozyme supplementation in diets that can be beneficial for Japanese quails (Coturnix coturnix japonica). Total one hundred and sixty Japanese quails at 43 days of age were used and divided randomly into 4 replicate groups each containing 32 animals. The experimental groups as follows: control group was feed a basal diet, royal jelly group was added to the water with 500 mg/kg diet, propolis group was feed orally ...

  15. Protective Effects of Royal Jelly and Vitamin C against Experimental Hemolytic Anemia on Sex Hormones and Histochemical Testicle Tissue Histochemistry of Adult Mice

    Directory of Open Access Journals (Sweden)

    H Anbara

    2016-03-01

    Full Text Available Introduction: Phenylhydrazine (PHZ is a well-known hemolytic compound inducing intoxication in erythrocytes. Therefore, the present study aimed to evaluate the protective effects of royal jelly and vitamin C against phenylhydrazine-induced damages in mouse testicles. Methods: In this study, 64 adult male mice were randomly and equally assigned to eight groups. The first group received normal saline (0.1ml intraperitoneally. The second group received PHZ (6 mg/100 gr intraperitoneally in 48-hour intervals. The third group received vitamin C (250 mg/kg/day intraperitoneally perday a long with PHZ. The fourth group received royal jelly (100 mg/kg/day through gavage. The fifth group received PHZ along with vitamin C and royal jelly in similar doses to the previous groups. The sixth group received only vitamin C, the seventh group recieved only royal jelly, and finally the eighth group received similar doses of vitamin C and royal jelly. After 35 days, serum and tissue samples were taken and used for histochemical (Mallory-Azan, Alkaline phosphatase, Oil red-O and PAS, and serum analyses (Testosterone, LH, FSH. Results: The study results revealed the histochemical changes in testicular tissue of the phenylhydrazine group, in which vitamin C and royal jelly partly improved the changes. Furthermore, serum analyses demonstrated a significant decrease in testosterone, FSH and LH levels, which this decrease was diminished by royal jelly and vitamin C. Conclusions: Royal jelly and vitamin C seem to have the potential to decrease serum and tissue damages induced by phenylhydrazine via restraining free radicals.

  16. An Empirical Study on the Influence of E-service Quality on Customers Trust: a study of Royal Jordanian airline service website

    OpenAIRE

    Jallouqa, Omar

    2013-01-01

    This Thesis is a study for the behavior of royal Jordanian airlines passengers using the online services and booking system it, investigates the value of royal Jordanian website quality and impact on passengers trust; it also examines the importance of five factors regarding e-services trust (Ease of use, Reputation, Privacy and Security, Responsiveness,Information quality )passengers who choose to visit Jordan will want to try the flag carrier as it represents spirit of the country, and befo...

  17. Clinical Evaluation of a Royal Jelly Supplementation for the Restoration of Dry Eye: A Prospective Randomized Double Blind Placebo Controlled Study and an Experimental Mouse Model

    Science.gov (United States)

    Inoue, Sachiko; Kawashima, Motoko; Hisamura, Ryuji; Imada, Toshihiro; Izuta, Yusuke; Nakamura, Shigeru; Ito, Masataka; Tsubota, Kazuo

    2017-01-01

    Background Dry eye is a multifactorial disease characterized by ocular discomfort and visual impairment. Lacrimal gland function has been shown to decrease with aging, a known potent risk factor for dry eye. We have previously found that orally administrated royal jelly (RJ) restored tear secretion in a rat model of dry eye. Methods and Findings We examined the effects of RJ oral administration on dry eye in this prospective, randomized, double-blind, placebo-controlled study. Forty-three Japanese patients aged 20–60 years with subjective dry eye symptoms were randomized to an RJ group (1200 mg/tablet, six tablets daily) or a placebo group for 8 weeks. Keratoconjunctival epithelial damage, tear film break-up time, tear secretion volume, meibum grade, biochemical data, and subjective dry eye symptoms based on a questionnaire were investigated at baseline, and at 4 and 8 weeks after intervention. Adverse events were reported via medical interviews. In the RJ group, tear volume significantly increased after intervention (p = 0.0009). In particular, patients with a baseline Schirmer value of ≤10 mm showed a significant increase compared with baseline volume (p = 0.0005) and volume in the placebo group (p = 0.0051). No adverse events were reported. We also investigated the effect of RJ (300 mg/kg per day) administration using a mouse model of dry eye. Orally repeated administration of RJ preserved tear secretion, potentially through direct activation of the secretory function of the lacrimal glands. Conclusion Our results suggest that RJ improves tear volume in patients with dry eye. Trial Registration Registered NO. the University Hospital Medical Information Network in Japan (UMIN000014446) PMID:28060936

  18. Clinical Evaluation of a Royal Jelly Supplementation for the Restoration of Dry Eye: A Prospective Randomized Double Blind Placebo Controlled Study and an Experimental Mouse Model.

    Science.gov (United States)

    Inoue, Sachiko; Kawashima, Motoko; Hisamura, Ryuji; Imada, Toshihiro; Izuta, Yusuke; Nakamura, Shigeru; Ito, Masataka; Tsubota, Kazuo

    2017-01-01

    Dry eye is a multifactorial disease characterized by ocular discomfort and visual impairment. Lacrimal gland function has been shown to decrease with aging, a known potent risk factor for dry eye. We have previously found that orally administrated royal jelly (RJ) restored tear secretion in a rat model of dry eye. We examined the effects of RJ oral administration on dry eye in this prospective, randomized, double-blind, placebo-controlled study. Forty-three Japanese patients aged 20-60 years with subjective dry eye symptoms were randomized to an RJ group (1200 mg/tablet, six tablets daily) or a placebo group for 8 weeks. Keratoconjunctival epithelial damage, tear film break-up time, tear secretion volume, meibum grade, biochemical data, and subjective dry eye symptoms based on a questionnaire were investigated at baseline, and at 4 and 8 weeks after intervention. Adverse events were reported via medical interviews. In the RJ group, tear volume significantly increased after intervention (p = 0.0009). In particular, patients with a baseline Schirmer value of ≤10 mm showed a significant increase compared with baseline volume (p = 0.0005) and volume in the placebo group (p = 0.0051). No adverse events were reported. We also investigated the effect of RJ (300 mg/kg per day) administration using a mouse model of dry eye. Orally repeated administration of RJ preserved tear secretion, potentially through direct activation of the secretory function of the lacrimal glands. Our results suggest that RJ improves tear volume in patients with dry eye. Registered NO. the University Hospital Medical Information Network in Japan (UMIN000014446).

  19. 877-Royal Decree 1753/1987 of 25 November partly amending the Regulations on health protection against ionizing radiation, approved by Royal Decree 2519/1982 of 12 August

    International Nuclear Information System (INIS)

    1988-01-01

    This Decree modifies the 1982 Royal Decree on Radiation Protection as a result of Spain's entry into the European Community and its taking into account of EURATOM Radiation Protection Directives 80/836. The 1987 Decree amends relevant provisions of the 1982 Decree to reflect the basic safety standards of the EURATOM Directives concerning the types of activities which imply exposure, the justification and optimisation of exposure and the requirement that individual doses not exceed specified limits. The annual dose equivalent limits are set out in Annex II to the Decree while Annex III gives the annual limits of intake by inhalation and ingestion for workers and members of the public [fr

  20. 17 June 1992 - Royal Order amending the Royal Order of 28 February 1963 laying down the General Regulations for protection of the population and workers against the hazards of ionizing radiation

    International Nuclear Information System (INIS)

    1992-01-01

    This Royal Order replaces certain provisions of the General Regulations for protection of the population and workers against the hazards of ionizing radiations. The new provisions concern the monitoring of radioactivity in the national territory and population dose, as well as monitoring of the population as a whole. The purpose of this amendment is to conform without delay to the Opinion of the Commission of the European Communities; the amendment concerns mainly the monitoring of doses received by the population and the technical conditions for such monitoring. (NEA)

  1. Looking back on a successful project. The Restoration of the Royal Palace in Amsterdam

    Directory of Open Access Journals (Sweden)

    Bert van Bommel

    2013-06-01

    Full Text Available After 1968, few changes were made to the Royal Palace in Amsterdam and eventually the palace was no longer functionally and technically up-to-date. Initially, the most recent restoration was only aimed at remedying that situation. Also, the project was split up and priority was given to fixing up the interior. Gradually, the actual restoration gained prominence. In 2007 it was decided to also restore the 1808 furniture. Until 2006, the government architect had hardly been involved in the restoration of the interior. This architect, Krijn van den Ende, was advised by various committees. Prior restorations (1929-1939 and 1960-1968 had restored the palace to its 17th-century state as best as possible. The most recent restoration respected this, while at the same time it aimed at connecting the 17th century character of the building to the unique collection of Empire furniture. This furniture was restored, as were the chandeliers and candelabras. All the ceilings on the first floor were studied and treated and the paintings between the beams were meticulously restored. A very important aspect was the restoration of the so-called ‘Bataven’ series in the galleries. Much of the work concerned making the building conform to contemporary standards. Once again the palace is now a suitable venue for official occasions. The inevitable addition of a lift did however cause quite a stir. Accessibility was improved and more representative rooms are now open to the public than before. The government architect was involved already in the preparatory stages of the second part of the restoration, which concerned the façades and the roofs. In executing the actual work a support committee provided advice and direction on his behalf. Although the sandstone is generally of a high quality, before 1968 a limited number of deteriorating blocks had been replaced. This time too, a number of blocks needed attention. The heavy scaffolding that needed to be installed for

  2. The EUI Data Center at the Royal Observatory of Belgium: challenges and solutions

    Science.gov (United States)

    Verbeeck, Cis; Stegen, Koen; Berghmans, David; West, Matthew; Kraaikamp, Emil; Gissot, Samuel; Giordanengo, Boris; Nicula, Bogdan

    ESA’s Solar Orbiter mission is conceived to perform a close-up study of the Sun and the inner heliosphere. With a perihelion close at 0.29 AU and a maximum aphelion at about 0.85 AU, Solar Orbiter ventures closer to the Sun than any spacecraft before. Furthermore, about 3 years after launch, the spacecraft will begin an out-of-ecliptic phase, with inclinations gradually increasing up to 30 degrees. Solar Orbiter will be launched in 2017 and its nominal mission will last until 2024 (with the possibility of an extended mission until 2026). It will provide unique data and imagery of the Sun. The Extreme Ultraviolet Imager (EUI) suite onboard Solar Orbiter is composed of two High Resolution Imagers (HRI, one at Lyman-alpha and one at 174 Angstrom), and one dual band Full-Sun imager (FSI) working alternatively at the 174 and 304 Angstrom EUV passbands. The EUI Data Center (EDC), under PI supervision and located at the Royal Observatory of Belgium (Brussels), will be the single point of contact for instrument planning activities and for data deliveries to the Solar Orbiter archive at ESAC (Madrid), and is currently in its design phase. The EUI Data Center will be responsible for delivery to ESAC and the maintenance of the pipeline software that will process EUI data from telemetry packets to higher level data products. It will also ensure the delivery of these data products to the Solar Orbiter Data Archive, and maintain the instrument user manual that documents the processing of EUI non-science TM packets at ESOC (Darmstadt). The EDC will monitor any anomaly affecting the EUI instrument and produce on a regular basis the Instrument Operations Reports including an instrument health and science performance review. Here, we present an overview of the EDC and how it envisages to tackle some specific challenges. Since EUI will only observe during three “science windows” of 10 days each per orbit of about 165 days and in view of a severely limited telemetry, it is

  3. Respiratory quotient: innovative method for monitoring ‘Royal Gala’ apple storage in a dynamic controlled atmosphere

    Directory of Open Access Journals (Sweden)

    Anderson Weber

    2015-02-01

    Full Text Available Apples (Malus domestica, Borkh. which are not stored at low temperature or in a properly controlled atmosphere (CA may have a high metabolic rate during the postharvest stage resulting in losses in quality. The aim of this study was to evaluate the quality of ‘Royal Gala’ apple fruit stored in accordance with a new method of dynamic controlled atmosphere (DCA.The respiratory quotient (RQ was monitored at two temperatures which were then compared using a commercially available technology based on chlorophyll fluorescence DCA (DCA-CF and static CA. Ethylene production and respiration rates were lower in apples stored in DCA than in CA, as a result of lower 1-aminocyclopropane-1-carboxylate oxidase activity, especially in apples stored in DCA-RQ2. Flesh firmness of apples stored in DCA did not differ from those stored in CA. Apples stored at 1 °C had less flesh breakdown occurrence and a high percentage of healthy fruit. ‘Royal Gala’ stored at DCA-RQ2 had less flesh breakdown than apples stored in CA; however, the apples stored in DCA-CF did not differ from those stored in DCA-RQ2 and CA. Apples stored at the highest RQ value (6 and 4, especially at 0.5 °C, had low O2 injury occurrence after storage. However the increase in temperature to 1.0 °C, reduced the occurrence of this disorder. Therefore, storage in DCA-RQ2 at 1 °C or DCA-CF at 0.5 °C are the recommendations of preference for ensuring maintenance of quality in ‘Royal Gala’ apples after eight months of storage.

  4. Decline of heterozygosity in a large but isolated population: a 45-year examination of moose genetic diversity on Isle Royale

    Directory of Open Access Journals (Sweden)

    Renae L. Sattler

    2017-07-01

    Full Text Available Wildlife conservation and management approaches typically focus on demographic measurements to assess population viability over both short and long periods. However, genetic diversity is an important predictor of long term population vitality. We investigated the pattern of change in genetic diversity in a large and likely isolated moose (Alces alces population on Isle Royale (Lake Superior from 1960–2005. We characterized samples, partitioned into five different 5-year periods, using nine microsatellite loci and a portion of the mtDNA control region. We also simulated the moose population to generate a theoretical backdrop of genetic diversity change. In the empirical data, we found that the number of alleles was consistently low and that observed heterozygosity notably declined from 1960 to 2005 (p = 0.08, R2 = 0.70. Furthermore, inbreeding coefficients approximately doubled from 0.08 in 1960–65 to 0.16 in 2000–05. Finally, we found that the empirical rate of observed heterozygosity decline was faster than the rate of observed heterozygosity loss in our simulations. Combined, these data suggest that genetic drift and inbreeding occurred in the Isle Royale moose populations over the study period, leading to significant losses in heterozygosity. Although inbreeding can be mitigated by migration, we found no evidence to support the occurrence of recent migrants into the population using analysis of our mtDNA haplotypes nor microsatellite data. Therefore, the Isle Royale moose population illustrates that even large populations are subjected to inbreeding in the absence of migration.

  5. Radiology standards for primary dental care: report by the Royal College of Radiologists and the National Radiological Protection Board

    International Nuclear Information System (INIS)

    Hudson, Tony

    1994-01-01

    In 1992 a joint venture between the Royal College of Radiologists (RCR) and the National Radiological Protection Board (NRPB) resulted in the formation of a Working Party (WP) to consider dental radiology. Although individual doses to patients are low, WP identified considerable scope for reducing the collective dose to patients and for improving the diagnostic quality of radiographs. The report published in the Documents of the NRPB series presents the WP conclusions in the form of guidelines that deal with all aspects of dental radiology in primary dental care. (Author)

  6. 28 April 1986: Royal Order determining the certificate of financial security for the carriage of nuclear substances

    International Nuclear Information System (INIS)

    1986-01-01

    The purpose of this Royal Order is to ensure that financial security certificates given by the nuclear operators liable to carriers of nuclear substances conform to the conditions set out in Article 4(c) of the Paris Convention on Third Party Liability in the field of Nuclear Energy. This is a requirement under the Belgian Act of 22nd July 1985 on Third Party Liability in the field of Nuclear Energy. The Annex to the Order contains a model certificate reproducing the type of information required in accordance with the Paris Convention. (NEA) [fr

  7. The Royal College of Pathologists of Australasia Quality Assurance Program: Immunohistochemistry Breast Marker Audit Overview 2005-2015.

    Science.gov (United States)

    Haffajee, Zenobia Ayesha Mohamed; Kumar, Beena; Francis, Glenn; Peck, Martyn; Badrick, Tony

    2017-11-20

    The Royal College of Pathologists of Australasia Quality Assurance Program (RCPAQAP) Anatomical Pathology provides a comprehensive External Quality Assurance (EQA) exercise to review the reporting of immunohistochemistry (IHC) and in-situ hybridization (ISH) breast markers through an audit of clinical results. The aim of this exercise was to provide information regarding the quality of breast marker testing within clinical laboratories from 2005 to 2015. This comprehensive audit included estrogen, progesterone, and HER2 marker reporting. This was an important quality assurance activity established in response to ongoing difficulties experienced in laboratories in this area of testing.

  8. Three Licentiates of the Royal College of Surgeons of Edinburgh who were decorated with the Victoria Cross.

    Science.gov (United States)

    Kaufman, M H

    2011-08-01

    Since the Victoria Cross was introduced in January 1856 by Queen Victoria to reward acts of valour in the face of the enemy, initially during the Crimean War, over 1350 medals have been awarded. Of these, three were awarded to medical officers who had previously gained the Licentiate Diploma of the Royal College of Surgeons of Edinburgh (LRCS Edin) - Valentine Munbee McMaster on 25 September 1857, Henry Thomas Sylvester on 20 November 1857 (although the acts of valour for which he was awarded his VC occurred on two occasions in September 1855) and Campbell Mellis (or Millis) Douglas on 7 May 1867.

  9. 26183 - Royal Decree 2519/1982 of 12 August approving the Regulations on Protection Against Ionizing Radiation

    International Nuclear Information System (INIS)

    1981-01-01

    This Royal Decree approves the Regulations on Protection against Ionizing Radiation. The purpose of the Regulations is to implement the radiation protection principles laid down in the framework Act on Nuclear Energy of 29th April 1964, as amended. They supersede all existing national rules in the same field and contain administrative and technical provisions governing nuclear and radioactive installations and activities, including the use of radiation-emitting equipment. They were made in compliance with the most recent international regulations on radiation protection and safety, in particular the Recommendations of the International Atomic Energy Agency (IAEA); the Regulations also take into account the recent Euratom Directives. (NEA) [fr

  10. Aplicação da CLAE para determinação do ácido 10-Hidróxi-2-decenóico (10-HDA em geléia real pura e adicionada a mel brasileiro HPLC aplication for 10-HDA determination in pure royal jelly and honey with royal jelly

    Directory of Open Access Journals (Sweden)

    Shinnosuke Koshio

    2003-10-01

    Full Text Available The aim of this paper was to determine the 10-HDA in pure royal jelly and products containing royal jelly, using HPLC methodology. 10-HDA is the natural indicator of the presence of royal jelly in products and also gives the authenticity of pure royal jelly. The chromatographic conditions used were: isocratic system, C18-H column, auto sampler, diode array UV-VIS detector (225 nm, mobile phase with methanol/water (45:55, pH= 2.5 and a-naphtol as internal standard. The results obtained using laboratory samples for pure royal jelly were 2.37%, varying from 0.15% for honey with 10% of royal jelly to 2.10% for honey with 90% of royal jelly respectivelly. For commercial products, the 10-HDA content varied from no detectable to 0.026%. The recovery test presented a minumum of 100.44% The detection limit was 45.92 ng/mL and the quantification limit was 76.53 ng/mL.

  11. Management accounting and rationalisation in the Army: The case of Spanish Military Hospitals in the 18th century

    Directory of Open Access Journals (Sweden)

    Juan Baños Sánchez-Matamoros

    2014-01-01

    Full Text Available The present paper deals with one of the most neglected areas of research in accounting, that of the Army. In spite of the literature on industries related to the Army, not too much has been extended on the Army per se. For this reason, this paper analyses the process of rationalization developed in the 18th century in Spanish Army Hospitals, as a result of the bankruptcy of the Royal Finances. Due to this process, the Military Hospitals were the most developed in the country, and it led to the emergence of the Contralor (Controller within the hospital, and thus accounting was considered as an essential matter.

  12. Hospital Outpatient PPS Partial Hospitalization Program LDS

    Data.gov (United States)

    U.S. Department of Health & Human Services — Hospital Outpatient Prospective Payment System (OPPS) Partial Hospitalization Program LDS This file contains select claim level data and is derived from 2010 claims...

  13. Can hospitals compete on quality? Hospital competition.

    Science.gov (United States)

    Sadat, Somayeh; Abouee-Mehrizi, Hossein; Carter, Michael W

    2015-09-01

    In this paper, we consider two hospitals with different perceived quality of care competing to capture a fraction of the total market demand. Patients select the hospital that provides the highest utility, which is a function of price and the patient's perceived quality of life during their life expectancy. We consider a market with a single class of patients and show that depending on the market demand and perceived quality of care of the hospitals, patients may enjoy a positive utility. Moreover, hospitals share the market demand based on their perceived quality of care and capacity. We also show that in a monopoly market (a market with a single hospital) the optimal demand captured by the hospital is independent of the perceived quality of care. We investigate the effects of different parameters including the market demand, hospitals' capacities, and perceived quality of care on the fraction of the demand that each hospital captures using some numerical examples.

  14. Evaluation of royal jelly as an alternative to fetal bovine serum in cell culture using cell proliferation assays and live cell imaging.

    Science.gov (United States)

    Musa, Marahaini; Nasir, Nurul Fatihah Mohamad; Thirumulu, Kannan Ponnuraj

    2014-01-01

    Royal jelly is a nutritious substance produced by the young nurse bees and contains significant amounts of proteins which are important for cell growth and proliferation. The aim of this study was to evaluate the effect of royal jelly as an alternative to fetal bovine serum (FBS) in cell culture using cell proliferation assays and live cell imaging. MRC-5 cells were treated with various concentrations of royal jelly extract in MTT assay. The control groups were comprised of Alpha-Minimal Essential Medium (α-MEM) alone and α-MEM with 10% FBS. Subsequently, the cell proliferation was studied for 10 days using Alamar Blue assay and live cell imaging from 48 to 72 h. The population doubling time (PDT) was determined using trypan blue assay after live cell imaging. In MTT assay, 0.156 and 0.078 mg/ml of royal jelly produced higher cell viability compared to positive control group but were not significantly different (P > 0.05). In the Alamar Blue assay, 0.156 and 0.078 mg/ml of royal jelly produced greater percentage of reduction at day 3 even though no significant difference was found (P > 0.05). Based on live cell imaging, the PDT for positive, negative, 0.156 and 0.078 mg/ml of royal jelly groups were 29.09, 62.50, 41.67 and 41.67 h respectively. No significant difference was found in the PDT between all the groups (P > 0.05). Royal jelly does not exhibit similar ability like FBS to facilitate cell growth under the present test conditions.

  15. Looking back at the John Mitchell Crouch Fellowship: the most prestigious research award of the Royal Australasian College of Surgeons.

    Science.gov (United States)

    Boult, Margaret; Babidge, Wendy; Pleass, Susan; Scott, David

    2015-10-01

    The John Mitchell Crouch Fellowship is a generous endowment made to the Royal Australasian College of Surgeons (RACS) by the young neurosurgeon's family, following his death from a brain tumour. In this article, we examine the significance and legacy of the grant since its inception in 1979. This is the highest level of research fellowship awarded by the RACS recognizing early career excellence, as part of its significant research funding programme (over $1.7 million in 2015). John Mitchell Crouch recipients have been pioneers in various areas of medicine where they have developed new technologies, established research centres, improved patient safety and military surgery and embraced evidence-based medicine. The funds they received have directly contributed to research published in numerous highly respected peer-reviewed journals such as The New England Journal of Medicine; established new laboratories, helped fund clinical trials and allowed new directions of research to be pursued. Recipients of the John Mitchell Crouch Fellowship have been recognized with many awards including 11 Australian and New Zealand Honours to date. Many other significant research funds have been subsequently bestowed, including over 120 National Health Medical Research Council (NHMRC) grants to Australian and New Zealand recipients subsequent to their Fellowship. This article also shows the range of disciplines in which the award has supported cutting-edge research leading to benefits for patients and health care. © 2015 Royal Australasian College of Surgeons.

  16. Characterization of royal jelly proteins in both Africanized and European honeybees (Apis mellifera) by two-dimensional gel electrophoresis.

    Science.gov (United States)

    Sano, Osamu; Kunikata, Toshio; Kohno, Keizo; Iwaki, Kanso; Ikeda, Masao; Kurimoto, Masashi

    2004-01-14

    In this study, the proteins contained in royal jelly (RJ) produced by Africanized honeybees and European honeybees (Apis mellifera) haven been analyzed in detail and compared using two-dimensional gel electrophoresis, and the N-terminal amino acid sequence of each spot has been determined. Most spots were assigned to major royal jelly proteins (MRJPs). Remarkable differences were found in the heterogeneity of the MRJPs, in particular MRJP3, in terms of molecular weights and isoelectric points between the two species of RJ. Furthermore, during the determination of the N-terminal amino acid sequence of each spot, for the first time, MRJP4 protein has been identified, the existence of which had been only implied by cloning of its cDNA sequence. The presence of heterogeneous bands of glucose oxidase was also identified. Thus, the results suggest that two-dimensional gel electrophoresis provides a suitable method for the qualitative analysis of the proteins contained in RJ derived from different honeybee species.

  17. A Practitioner’s View of the Future of Organization Design: Future Trends and Implications for Royal Dutch Shell

    Directory of Open Access Journals (Sweden)

    Jan Steinmetz

    2012-05-01

    Full Text Available Humanity is facing an increasingly challenging outlook for energy needs and the planet. Royal Dutch Shell is a global group of energy and petrochemicals companies with approximately 100,000 employees in more than 80 countries that is committed to help meet the challenges of the new energy environment in a sustainable and responsible manner. My statement will present some of the future trends and possible implications which can be seen for organization design within Royal Dutch Shell (Shell and which are applicable to other large, complex enterprises. It largely represents the personal views and reflections of a practitioner both inside and outside of Shell’s human resources (HR function in the United States. Using the lens of organization design, we will review the themes that emerged from the Shell Energy 2025 and Shell Energy 2050 global scenarios. Next, we will discuss Shell’s previous experience, challenges, and issues related to organization design, and how the recent redesign of the HR function has provided wider space and crisper focus to meet the challenges of the future. Finally, we will review the design challenges that the future trends impose upon the organization design practice. Although these challenges and implications are derived from experience working in Shell and its joint ventures, they are not confined solely to Shell. Because many of the challenges discussed below would benefit from scholarly research, the statement represents a practitioner’s view on how the future of organization design may play out.

  18. AIR SEBAGAI ALAT PENGENDALI IKLIM MIKRO DALAM BANGUNAN Studi Kasus : Taman Sari Royal Heritage Spa, Hotel Sheraton Mustika Yogyakarta

    Directory of Open Access Journals (Sweden)

    Dyah Hendrawati

    2016-07-01

    Full Text Available Indonesia is a country with wet tropical climate has constraints in obtaining thermal comfort because of the high air temperature, high air humidity and lower air speed. Modification of the microclimate might be conducted by increasing the cooling effect in a passive manner. Water can be used as one of control strategy thermal to build the microclimate or to site. Water also played an important role in lowering temperature and raise humidity in a room in building.Taman Sari Royal Heritage Spa, which is located in Yogyakarta,is one of building that implementing water as thermal control by making pool in door. This research aims to understand the influence of water in controlling the micro climate and the anything influence it .This research uses the quantitative methods by conducting observation and measuring temperature and humidity directly to the research objects. Secondary data is needed in this research. There was also literature review on the stuff that supports research, and a literature study was also conducted. The research and analysis on the results shows that 1 .The room in Tamansari royal heritage spa still in comfort zone in thermal .2 .The volume of water affects temperatures and humidity room 3 .Distance is a significant factor.

  19. Whole-genome resequencing of honeybee drones to detect genomic selection in a population managed for royal jelly.

    Science.gov (United States)

    Wragg, David; Marti-Marimon, Maria; Basso, Benjamin; Bidanel, Jean-Pierre; Labarthe, Emmanuelle; Bouchez, Olivier; Le Conte, Yves; Vignal, Alain

    2016-06-03

    Four main evolutionary lineages of A. mellifera have been described including eastern Europe (C) and western and northern Europe (M). Many apiculturists prefer bees from the C lineage due to their docility and high productivity. In France, the routine importation of bees from the C lineage has resulted in the widespread admixture of bees from the M lineage. The haplodiploid nature of the honeybee Apis mellifera, and its small genome size, permits affordable and extensive genomics studies. As a pilot study of a larger project to characterise French honeybee populations, we sequenced 60 drones sampled from two commercial populations managed for the production of honey and royal jelly. Results indicate a C lineage origin, whilst mitochondrial analysis suggests two drones originated from the O lineage. Analysis of heterozygous SNPs identified potential copy number variants near to genes encoding odorant binding proteins and several cytochrome P450 genes. Signatures of selection were detected using the hapFLK haplotype-based method, revealing several regions under putative selection for royal jelly production. The framework developed during this study will be applied to a broader sampling regime, allowing the genetic diversity of French honeybees to be characterised in detail.

  20. Thomas Birch's ‘Weekly Letter’ (1741–66): correspondence and history in the mid-eighteenth-century Royal Society

    Science.gov (United States)

    Ellis, Markman

    2014-01-01

    Thomas Birch (1705–66), Secretary of the Royal Society from 1752 to 1765, and Philip Yorke, second Earl of Hardwicke (1720–90), wrote a ‘Weekly Letter’ from 1741 to 1766, an unpublished correspondence of 680 letters now housed in the British Library (Additional Mss 35396–400). The article examines the dimensions and purposes of this correspondence, an important conduit of information for the influential coterie of the ‘Hardwicke circle’ gathered around Yorke in the Royal Society. It explores the writers' self-conception of the correspondence, which was expressed in deliberately archaic categories of seventeenth-century news exchange, such as the newsletter, aviso and a-la-main. It shows how the letter writers negotiated their difference in status through the discourse of friendship, and concludes that the ‘Weekly Letter’ constituted for the correspondents a form of private knowledge, restricted in circulation to their discrete group, and as such unlike the open and networked model of Enlightenment science. PMID:25254279

  1. Royal jelly promotes DAF-16-mediated proteostasis to tolerate β-amyloid toxicity in C. elegans model of Alzheimer's disease.

    Science.gov (United States)

    Wang, Xiaoxia; Cao, Min; Dong, Yuqing

    2016-08-23

    Numerous studies have demonstrated that dietary intervention may promote health and help prevent Alzheimer's disease (AD). We recently reported that bee products of royal jelly (RJ) and enzyme-treated royal jelly (eRJ) were potent to promote healthy aging in C. elegans. Here, we examined whether RJ/eRJ consumption may benefit to mitigate the AD symptom in the disease model of C. elegans. Our results showed that RJ/eRJ supplementation significantly delayed the body paralysis in AD worms, suggesting the β-amyloid (Aβ) toxicity attenuation effects of RJ/eRJ. Genetic analyses suggested that RJ/eRJ-mediated alleviation of Aβ toxicity in AD worms required DAF-16, rather than HSF-1 and SKN-1, in an insulin/IGF signaling dependent manner. Moreover, RJ/eRJ modulated the transactivity of DAF-16 and dramatically improved the protein solubility in aged worms. Given protein solubility is a hallmark of healthy proteostasis, our findings demonstrated that RJ/eRJ supplementation improved proteostasis, and this promotion depended on the transactivity of DAF-16. Collectively, the present study not only elucidated the possible anti-AD mechanism of RJ/eRJ, but also provided evidence from a practical point of view to shed light on the extensive correlation of proteostasis and the prevention of neurodegenerative disorders.

  2. Les marbres dans la décoration du Palais royal de Madrid : origines et incidence

    Directory of Open Access Journals (Sweden)

    María Luisa Tárraga Baldó

    2012-09-01

    Full Text Available La construction du Palais royal de Madrid a marqué un tournant dans l’histoire de l’art espagnol. La décoration intérieure y a employé une profusion de marbres et de pierres ornementales choisies en raison de leur couleur ou de leur rareté. Au xviiie siècle, il est décidé de décorer tous les murs des salons principaux du palais afin de ne laisser aucune paroi sans marbre. La volonté d’imiter les marbriers italiens qui avaient exécuté le tabernacle et le retable de la chapelle de l’Escorial pour Philippe II est certainement présente. Ces œuvres ont depuis toujours constitué un motif d’orgueil national.Pour la décoration du Palais royal de Madrid, Philippe V et ses successeurs ont décidé de n’utiliser que des matériaux espagnols. Cette exclusivité a provoqué une véritable campagne d’exploration et d’exploitation géologique du territoire, qui a fourni une information exhaustive sur l’orographie nationale, jusqu’à ce que Ferdinand VI permette en 1748 l’ouverture des carrières privées pour continuer le chantier.

  3. Diffusion of Clinical Nutrition through scientific societies and journals. A round table at the Spanish Royal Academy of Pharmacy

    Directory of Open Access Journals (Sweden)

    Francisco J. Sánchez-Muniz

    2018-04-01

    Full Text Available This special article defines very briefly some central aspects of Artificial Nutrition as nutritional support in special situations in patients that are not able to maintain a sufficient digestive function to restore or maintain optimal nutritional status or in those malnourished or in the way to be. Subsequently it reviews the round table held in January 2018 at the headquarters of the Spanish Royal National Academy of Pharmacy, where this Royal Institution gave a tribute to Dr. Jesus M. Culebras, founder of the journal Nutricion Hospitalaria, and architect of many achievements and initiatives of the Sociedad Española de Nutrition Enteral and Parenteral of great importance in the field of Nutrition and Artificial Nutrition in Spain. Later, directives of the Journal Nutrición Hospitalaria, Farmacia Hospitalaria, Journal of Negative and No Positive Results and Anales de la Real Academia Nacional de Farmacia participated in a workshop. Emphasis was placed on the convenience of increasing collaboration between the journals and entities that they represent, especially with regard to the framework of Nutrition and also of Artificial feeding, insisting on the need to start a series of meetings in the very near future with the purpose of defining competences and rights, and taking joint positions in publications, consensus agreements that would guarantee the dissemination and visibility of this issue of enormous importance for health.

  4. Help prevent hospital errors

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000618.htm Help prevent hospital errors To use the sharing features ... in the hospital. If You Are Having Surgery, Help Keep Yourself Safe Go to a hospital you ...

  5. Quality of coroner's post-mortems in a UK hospital.

    Science.gov (United States)

    Al Mahdy, Husayn

    2014-01-01

    The aim of this paper was, principally, to look at the coroner's post-mortem report quality regarding adult medical patients admitted to an English hospital; and to compare results with Royal College of Pathologists guidelines. Hospital clinical notes of adult medical patients dying in 2011 and who were referred to the coroner's office to determine the cause of death were scrutinised. Their clinical care was also reviewed. There needs to be a comprehensive approach to coroner's post-mortems such as routinely taking histological and microbiological specimens. Acute adult medical patient care needs to improve. Steps should be taken to ensure that comprehensive coroner's post-mortems are performed throughout the UK, including with routine histological and microbiological specimens examination. Additionally, closer collaboration between clinicians and pathologists needs to occur to improve emergency adult medical patient clinical care. The study highlights inadequacies in coroner's pathology services.

  6. Additional measures do not improve the diagnostic accuracy of the Hospital Admission Risk Profile for detecting downstream quality of life in community-dwelling older people presenting to a hospital emergency department

    Directory of Open Access Journals (Sweden)

    Grimmer K

    2014-01-01

    Full Text Available K Grimmer, S Milanese, K Beaton, A AtlasInternational Centre for Allied Health Evidence, University of South Australia, Adelaide, SA, AustraliaIntroduction: The Hospital Admission Risk Profile (HARP instrument is commonly used to assess risk of functional decline when older people are admitted to hospital. HARP has moderate diagnostic accuracy (65% for downstream decreased scores in activities of daily living. This paper reports the diagnostic accuracy of HARP for downstream quality of life. It also tests whether adding other measures to HARP improves its diagnostic accuracy.Methods: One hundred and forty-eight independent community dwelling individuals aged 65 years or older were recruited in the emergency department of one large Australian hospital with a medical problem for which they were discharged without a hospital ward admission. Data, including age, sex, primary language, highest level of education, postcode, living status, requiring care for daily activities, using a gait aid, receiving formal community supports, instrumental activities of daily living in the last week, hospitalization and falls in the last 12 months, and mental state were collected at recruitment. HARP scores were derived from a formula that summed scores assigned to age, activities of daily living, and mental state categories. Physical and mental component scores of a quality of life measure were captured by telephone interview at 1 and 3 months after recruitment.Results: HARP scores are moderately accurate at predicting downstream decline in physical quality of life, but did not predict downstream decline in mental quality of life. The addition of other variables to HARP did not improve its diagnostic accuracy for either measure of quality of life.Conclusion: HARP is a poor predictor of quality of life.Keywords: functional decline, HARP, quality of life, older people

  7. Efeito do 1-metilciclopropeno na conservação de maçãs 'Royal Gala' em ar refrigerado e atmosfera controlada Effects of 1-methylcyclopropene on 'Royal Gala' apples stored in refrigerated air and controlled atmosphere

    Directory of Open Access Journals (Sweden)

    Adriana Regina Corrent

    2004-08-01

    Full Text Available Maçãs 'Royal Gala', colhidas em dois estádios de maturação, foram tratadas com 1-MCP (1-metilciclopropeno nas concentrações de 0; 625 e 1250 nL.L-1, durante 48 horas, à temperatura de 20 ± 2 ºC. Após este tratamento, foram armazenadas em dois diferentes sistemas: em atmosfera controlada à temperatura de 0 ± 0,5 ºC, 2,1 a 2,3 kPa de CO2 , 1,8 a 2,0 kPa de O2 e umidade relativa de 95 ± 5 %, durante 9 meses. Em ar refrigerado a 0,5 ± 0,5 ºC e 95 ± 5 % de umidade relativa, durante 8 meses. As análises realizadas demonstraram a eficiência do 1-MCP em controlar a maturação das frutas durante o armazenamento em ambas as condições e pontos de colheita. A aplicação do 1-MCP reduziu drasticamente a produção de etileno, diminuiu a perda de firmeza, além de preservar a acidez total titulável.In the present work were evaluated the effects of 1-MCP on 'Royal Gala' apples stored in refrigerated air and controlled atmosphere. 'Royal Gala' apples were harvested at two ripeness stages and treated with 1-methylcyclopropene (1-MCP using two concentrations 625 and 1250 nL.L-1 which were applied during 48 hours at temperature of 20 ± 2 ºC. The control fruit was only kept in air. After the treatments the apples were stored in either controlled atmosphere 2,1 to 2,3 kPa CO2, 1,8 to 2,0 kPa O2 and 95 ± 0,5 % of relative humidity for 9 months at 0 ± 0,5 ºC or in refrigerated air storage at 0,5 ± 0,5 ºC and 95 ± 0,5 % of relative humidity, for 8 months. The 1-MCP applications on apples in both storages and ripening stages reduced dramatically the ethylene production. Pulp firmness losses and titratable acidity were also significanthy higher compared to control fruit.

  8. 16 October 1991-Royal Order amending the Royal Order of 30 March 1981 determining the duties and fixing the operating conditions of the Public Body for the Management of Radioactive Waste and Fissile Materials

    International Nuclear Information System (INIS)

    1991-01-01

    The 1991 Royal Order amends and supplements the provisions of the 1981 0rder dealing with the duties and resources of ONDRAF, the National Body for the Management of Radioactive Waste and Fissile Materials. Its duties include, inter alia, treatment and conditioning of waste on behalf of producers without the necessary facilities, training of specialists for such work for the producers with such facilities, transport, storage and disposal of radioactive waste, transport, and storage of certain enriched fissile materials and plutonium-bearing materials. As regards decommissioned nuclear installations, ONDRAF must establish management programmes for the resulting waste and must also decommission a nuclear installation at the operator's request or if he defaults. (NEA)

  9. Turning Red Rural Landscapes Yellow? Sufficiency Economy and Royal Projects in the Hills of Nan Province, Northern Thailand

    Directory of Open Access Journals (Sweden)

    Amalia Rossi

    2012-01-01

    Full Text Available This paper discusses the efforts of the royal family to moralise the environmental behaviour of their subjects in the name of the Sufficiency Economy philosophy solicited by King Bhumibol since the 1990s in Thailand. Drawing on ethnographic fieldwork conducted in Nan province, Northern Thailand, in 2008 and 2009, I focus particularly on Royal Projects recently promoted to correct the rural practices of the ethnic minority groups living in the hills of Nan. In the past, many of these ethnic groups took part in the Maoist insurgency while at present, they represent a key basin of support- ers for the reformist Red Shirts movement which is currently threatening the role of the monarchy in Thai politics. The research suggests that the recently increased trend of staging new projects for sustainable agro-forestry management in a ‘red’ area as Nan does not only aim at improving the conditions of mountain peoples and of the environment, but simultaneously increases the political influence of the conservative forces over this ‘ungovernable’ territory in times of political crisis. ----- Dieser Artikel diskutiert die Bemühungen der königlichen Familie in Thailand seit den 1990-er Jahren, das Umweltverhalten ihrer Subjekte im Namen der Sufficiency Economy Philosophie von König Bhumibol zu moralisieren. Mit Bezug auf ethnografische Forschung in der Provinz Nan in Nordthailand in den Jahren 2008 und 2009 fokussiere ich insbesondere auf Royal Projects, die in letzter Zeit gefördert werden, um ländliche Praktiken ethnischer Minderheiten in den Bergen von Nan zu korrigieren. In der Vergangenheit waren viele dieser ethnischen Gruppen am maoistischen Aufstand beteiligt, während sie heute ein zentrales Auffangbecken für UnterstützerInnen der reformistischen Rothemden, die derzeit die Rolle der Monarchie in der thailändischen Politik in Frage stellen, darstellen. Die Forschung deutet an, dass der Trend zur Einführung von neuen Projekten f

  10. Advanced cell-based modeling of the royal disease: characterization of the mutated F9 mRNA.

    Science.gov (United States)

    Martorell, L; Luce, E; Vazquez, J L; Richaud-Patin, Y; Jimenez-Delgado, S; Corrales, I; Borras, N; Casacuberta-Serra, S; Weber, A; Parra, R; Altisent, C; Follenzi, A; Dubart-Kupperschmitt, A; Raya, A; Vidal, F; Barquinero, J

    2017-11-01

    Essentials The Royal disease (RD) is a form of hemophilia B predicted to be caused by a splicing mutation. We generated an iPSC-based model of the disease allowing mechanistic studies at the RNA level. F9 mRNA analysis in iPSC-derived hepatocyte-like cells showed the predicted abnormal splicing. Mutated F9 mRNA level was very low but we also found traces of wild type transcripts. Background The royal disease is a form of hemophilia B (HB) that affected many descendants of Queen Victoria in the 19th and 20th centuries. It was found to be caused by the mutation F9 c.278-3A>G. Objective To generate a physiological cell model of the disease and to study F9 expression at the RNA level. Methods Using fibroblasts from skin biopsies of a previously identified hemophilic patient bearing the F9 c.278-3A>G mutation and his mother, we generated induced pluripotent stem cells (iPSCs). Both the patient's and mother's iPSCs were differentiated into hepatocyte-like cells (HLCs) and their F9 mRNA was analyzed using next-generation sequencing (NGS). Results and Conclusion We demonstrated the previously predicted aberrant splicing of the F9 transcript as a result of an intronic nucleotide substitution leading to a frameshift and the generation of a premature termination codon (PTC). The F9 mRNA level in the patient's HLCs was significantly reduced compared with that of his mother, suggesting that mutated transcripts undergo nonsense-mediated decay (NMD), a cellular mechanism that degrades PTC-containing mRNAs. We also detected small proportions of correctly spliced transcripts in the patient's HLCs, which, combined with genetic variability in splicing and NMD machineries, could partially explain some clinical variability among affected members of the European royal families who had lifespans above the average. This work allowed the demonstration of the pathologic consequences of an intronic mutation in the F9 gene and represents the first bona fide cellular model of HB allowing the

  11. An Analysis of the hemophilia of the royal families of Europe, its startling implication and dentistry's role in treating the hemophiliac patient.

    Science.gov (United States)

    Maloney, William James; Raymond, George; Hershkowitz, David; Rochlen, Glenn

    2015-03-01

    Hemophilia is an inherited x-linked recessive disorder. It is known popularly as "The Royal Disease," as it has affected many of the royal families of Europe by virtue of Queen Victoria being a carrier for the gene and, subsequently, passing it on to her offspring. They, in turn, married and had children with other royal families of Europe. Hemophilia is certainly not limited to royalty. There are many hemophiliacs living in our communities, and they must receive both proper dental home-care education and dental treatment in order to prevent possibly life-threatening emergency dental episodes. Individuals with hemophilia pose different management issues to the dental professional. The various precautions and modifications that must be taken in order to ensure the safe delivery of dental care to hemophiliac dental patients are discussed.

  12. The UK Government response to the Royal Commission on Environmental Pollution's twenty-second report: energy - the changing climate

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-02-01

    The Royal Commission on Environmental Pollution's Twenty Second Report 'Energy - the Changing Climate' was presented to Parliament in June 2000. The report advocates a transformation in the use of energy in the UK to counter climate change. As a contribution to global efforts to prevent excessive climate change, the Royal Commission recommends that the UK should plan to reduce carbon dioxide emissions by some 60% from current levels by about 2050. The Report explores what this will mean for industry and households and highlights how Government policies need to change. This document provides the Government's formal response to the Twenty Second Report. The response summarises the action being taken and proposed, and it relates to the Royal Commission's recommendations. Its structure is thematic, rather than being a point-by-point response. This allows the action to be described coherently, but maintains the link with the recommendations.

  13. Hospital marketing revisited.

    Science.gov (United States)

    Costello, M M

    1987-05-01

    With more hospitals embracing the marketing function in their organizational management over the past decade, hospital marketing can no longer be considered a fad. However, a review of hospital marketing efforts as reported in the professional literature indicates that hospitals must pay greater attention to the marketing mix elements of service, price and distribution channels as their programs mature.

  14. Hospital Library Administration.

    Science.gov (United States)

    Cramer, Anne

    The objectives of a hospital are to improve patient care, while the objectives of a hospital library are to improve services to the staff which will support their efforts. This handbook dealing with hospital administration is designed to aid the librarian in either implementing a hospital library, or improving services in an existing medical…

  15. La couleur des palais royaux espagnols du xvie au xviiie siècle The colour of Spanish royal palaces from the sixteenth to eighteenth centuries

    Directory of Open Access Journals (Sweden)

    Juan Hernández Ferrero

    2008-05-01

    Full Text Available En Espagne, l’architecture des châteaux royaux, monochrome, n’accorde aucune véritable importance esthétique à la couleur. Ainsi, le monastère de l’Escurial, également palais royal, utilise le gris (teinte quelque peu modifiée de nos jours comme élément conférant une uniformité architecturale. Mais, au cours du xviie siècle, les façades du nouveau palais du Buen Retiro reçoivent une coloration discrète qui vise à les mettre en valeur. La couleur intègre alors le vocabulaire des architectes pour finalement s’affirmer dans l’usage au xviiie siècle, comme nous le verrons avec les palais royaux de Madrid, du Pardo, de Riofrío et de La Granja de San Ildefonso. Ainsi se trouve contredite la théorie initiale d’absence de couleur dans les résidences royales d’Espagne. Cette évolution est le fruit de l’influence européenne sur l’art espagnol.In Spain, the monochromatic architecture of royal chateaux placed no real aesthetic importance on colour. The El Escurial monastery, also a royal palace, used the colour grey (a tone somewhat modified today to provide an architectural uniformity. But during the seventeenth century the facades of the new Buen Retiro palace were given a discreet colouring that aimed to enhance them. Colour began to be used by architects, and widely so in the eighteenth century, as we will see with the royal palaces of Madrid, El Pardo, Riofrío and La Granja de San Ildefonso – contradicting the initial theory that colour was absent from the royal residences of Spain. This development was a result of the European influence on Spanish art.

  16. The Efficacy of Specific Essential Oils on Yeasts Isolated from the Royal Tomb Paintings at Tanis, Egypt

    Directory of Open Access Journals (Sweden)

    Akmal Ali SAKR

    2012-06-01

    Full Text Available Yeast strains play an important role in the biodeterioration and biodegradation of paintings in ancient Egyptian tombs. Thirteen yeast were isolated from the royal tombs at Tanis (Oserkon II, Psunes and Shashanq, Sharkia Governorate, Egypt, dated back to 840 B.C., by using a sterile cotton swab. Those strains were identified as Saccharomyces cerevisiae, Candida albicans, C. lipolytica and Lodderomyces elongspous. The S. cerevisiae strains were halotolerant for sodium chloride, up to 10 %. Moreover, they caused a fading for the azurite blue color in laboratory cultures and S. cerevisiae was the most potent agent in fading the color. Five essential oils (lemon, spearmint, fennel, marjonam and rosemary were used to control their growth. Spearmint and lemon oils were the most effective oils in inhibiting the growth of those strains, whereas marjonam, fennel and rosemary had no effect on their growth.

  17. Palliative sedation: not just normal medical practice. Ethical reflections on the Royal Dutch Medical Association's guideline on palliative sedation.

    Science.gov (United States)

    Janssens, Rien; van Delden, Johannes J M; Widdershoven, Guy A M

    2012-11-01

    The main premise of the Royal Dutch Medical Association's (RDMA) guideline on palliative sedation is that palliative sedation, contrary to euthanasia, is normal medical practice. Although we do not deny the ethical distinctions between euthanasia and palliative sedation, we will critically analyse the guideline's argumentation strategy with which euthanasia is demarcated from palliative sedation. First, we will analyse the guideline's main premise, which entails that palliative sedation is normal medical treatment. After this, we will critically discuss three crucial propositions of the guideline that are used to support this premise: (1) the patient's life expectancy should not exceed 2 weeks; (2) the aim of the physician should be to relieve suffering and (3) expert consultation is optional. We will conclude that, if inherent problematic aspects of palliative sedation are taken seriously, palliative sedation is less normal than it is now depicted in the guideline.

  18. Meeting the challenge of future energy supply from the perspective of Royal Dutch Shell. An interview with Matthias Bichsel

    Energy Technology Data Exchange (ETDEWEB)

    Bollinger, D. (ed.); Gunzenhauser, B. [Vice-President of the Association of Swiss Petroleum Geologists and Engineers, c/o Interoil AG, Zuerich (Switzerland)

    2009-07-01

    In this comprehensive interview in the Swiss Bulletin for Practical Geology with Matthias Bichsel, Director of Projects and Technology at Royal Dutch Shell plc, the subject of 'Peak Oil' is discussed. The question is asked on how Shell deals with the fact that oil and gas resources are limited and sooner or later will be more or less depleted or can only be used at high cost. A further topic discussed deals with how Shell wants to satisfy current shareholder interests. At the same time the company needs to be led into a viable and successful future. Shell's efforts to position itself in this difficult situation are discussed. The development of resource estimates, environmental responsibility and sustainability are further topics examined. Current scenarios are looked at and how Shell aims to solve the dilemma of meeting doubling energy demand is discussed. Finally, new technologies and renewable alternatives are looked at

  19. Radiofrequency exposure on fast patrol boats in the Royal Norwegian Navy--an approach to a dose assessment.

    Science.gov (United States)

    Baste, Valborg; Mild, Kjell Hansson; Moen, Bente E

    2010-07-01

    Epidemiological studies related to radiofrequency (RF) electromagnetic fields (EMF) have mainly used crude proxies for exposure, such as job titles, distance to, or use of different equipment emitting RF EMF. The Royal Norwegian Navy (RNoN) has measured RF field emitted from high-frequency antennas and radars on several spots where the crew would most likely be located aboard fast patrol boats (FPB). These boats are small, with short distance between the crew and the equipment emitting RF field. We have described the measured RF exposure aboard FPB and suggested different methods for calculations of total exposure and annual dose. Linear and spatial average in addition to percentage of ICNIRP and squared deviation of ICNIRP has been used. The methods will form the basis of a job exposure matrix where relative differences in exposure between groups of crew members can be used in further epidemiological studies of reproductive health. 2010 Wiley-Liss, Inc.

  20. Virtopsy shows a high status funerary treatment in an early 18th Dynasty non-royal individual.

    Science.gov (United States)

    Loynes, Robert D; Charlier, Philippe; Froesch, Philippe; Houlton, Tobias M R; Lallo, Rudy; Di Vella, Giancarlo; Bianucci, Raffaella

    2017-09-01

    This work presents the multidisciplinary investigation of the head of Nebiri (Museo Egizio, Turin S_5109), Chief of Stables, a high status elite person from the 18th Dynasty involving MDCT, 3D brain surface and facial reconstructions accompanied by a consideration of previously presented chemical analysis of the embalming materials found in fragments of bandages used on the head and viscera (lung) found in one of the four canopic jars. Comparison of the techniques used for the cosmetic treatment of Nebiri with those used in other elite and high status non-royal persons confirms the validity of the use of the term "high status elite" in the case of Nebiri. This case highlights the importance of using modern forensic techniques both to enhance new technologies of retrospective diagnosis on altered human remains and to increase knowledge of past populations.

  1. New porcellioidean gastropods from early Devonian of Royal Creek area, Yukon Territory, Canada, with notes on their early phylogeny

    Science.gov (United States)

    Fryda, J.; Blodgett, R.B.; Lenz, A.C.; Manda, S.

    2008-01-01

    This paper presents a description of new gastropods belonging to the superfamily Porcellioidea (Vetigastropoda) from the richly diverse Lower Devonian gastropod fauna of the Road River Formation in the Royal Creek area, Yukon Territory. This fauna belongs to Western Canada Province of the Old World Realm. The Pragian species Porcellia (Porcellia) yukonensis n. sp. and Porcellia (Paraporcellia) sp. represent the oldest presently known members of subgenera Porcellia (Porcellia) and Porcellia (Paraporcellia). Their simple shell ornamentation fits well with an earlier described evolutionary trend in shell morphology of the Porcellinae. Late Pragian to early Emsian Perryconcha pulchra n. gen. and n. sp. is the first member of the Porcellioidea bearing a row of tremata on adult teleoconch whorls. The occurrence of this shell feature in the Porcellioidea is additional evidence that the evolution of the apertural slit was much more complicated than has been proposed in classical models of Paleozoic gastropod evolution. Copyright ?? 2008, The Paleontological Society.

  2. Hearing with an atympanic ear: good vibration and poor sound-pressure detection in the royal python, Python regius

    DEFF Research Database (Denmark)

    Christensen, Christian Bech; Christensen-Dalsgaard, Jakob; Brandt, Christian

    2012-01-01

    are sensitive to sound pressure and (2) snakes are sensitive to vibrations, but cannot hear the sound pressure per se. Vibration and sound-pressure sensitivities were quantified by measuring brainstem evoked potentials in 11 royal pythons, Python regius. Vibrograms and audiograms showed greatest sensitivity...... at low frequencies of 80-160 Hz, with sensitivities of -54 dB re. 1 m s(-2) and 78 dB re. 20 μPa, respectively. To investigate whether pythons detect sound pressure or sound-induced head vibrations, we measured the sound-induced head vibrations in three dimensions when snakes were exposed to sound...... pressure at threshold levels. In general, head vibrations induced by threshold-level sound pressure were equal to or greater than those induced by threshold-level vibrations, and therefore sound-pressure sensitivity can be explained by sound-induced head vibration. From this we conclude that pythons...

  3. Relationship between tooth value and skin color in patients visiting Royal Medical Services clinics of Jordan.

    Science.gov (United States)

    Al-Nsour, Hind Fahed; Al-Zoubi, Tamara Trad; Al-Rimawi, Ali Salaheddin

    2018-03-01

    Facial and dental aesthetics are becoming of great concern for patients, especially for the younger generation. Tooth color matching and selection is considered a vital element in order to create an attractive beautiful smile. The importance of tooth color matching is to adjust tooth colors to obtain a good match with adjacent teeth and the skin. This is considered a challenge especially if adjacent teeth were lost or records of patients' teeth color were not available. The aim of this study was to determine the relationship between skin complexion and tooth value in a Jordanian population. A cross-sectional study of 520 individuals who were randomly selected and belonging to different age groups, ranging from 15-65 years, with equal sex distribution. These patients visited the dental clinics at different Jordanian military hospitals. The study was carried out over a period of one year from 2015 to 2016. The randomly selected sample was examined by one researcher. Shade of the middle third of the labial surface of central incisor was determined visually using VITA tooth guide, 3D-MASTER shade guide. Tooth shades were divided into two categories according to their value. The skin complexion was identified using Fitzpatrick skin type test, and was categorized into two categories (fair and dark). Data were statistically analyzed using Epi Info version 6. A statistically significant tooth shade value difference was discovered among subjects of different skin color (pvalue among a Jordanian population. Thus, considering the skin complexion when choosing tooth shades is helpful in achieving a pleasing good-looking smile, yet further investigations in this field must be carried out.

  4. Residential aged care residents and components of end of life care in an Australian hospital.

    Science.gov (United States)

    Leong, Laurence Jee Peng; Crawford, Gregory Brian

    2018-06-09

    With ageing of Australians, the numbers of residential aged care (RAC) residents is rising. This places a spotlight on decisions about appropriate care for this population, including hospitalisation and end-of-life (EOL) care. The aim was to study a sample of RAC residents who attended and died in hospital, to quantify measurable components of EOL care so as to describe the extent of palliative care required. A retrospective case-note review of hospital records was conducted in Adelaide, Australia. Participants were 109 RAC residents who attended from July 2013 to June 2014 and died in hospital. Measurements were advance care planning, health care input from the RAC facilities to hospital and components of EOL care. Residents with and without advanced dementia were compared. Advance care directives (ACDs) were present from 11 to 50%, and advance care plans (ACPs) at 60%. There were more ACPs, resuscitation orders (for/against) and do-not-hospitalise orders in residents with advanced dementia than those without. General practitioner (GP) and extended care paramedic (ECP) input on decisions for hospital transfer were 30% and 1 %. Mean hospital stay to death was 5.2 days. For residents admitted under non-palliative care teams, specialist palliative care (SPC) was needed for phone advice in 5%, consultation in 45%, transfer to palliative care unit in 37%, and takeover by SPC team in 19%. Mean number of documented goals-of-care discussions with family/caregiver was 1.7. In the last 3 days of life, the mean daily number of doses of EOL medications was 4.2. Continuous subcutaneous infusion was commenced in 35%. Staff in RAC need to be adequately resourced to make complex decisions about whether to transfer to hospital. RAC nurses are mainly making these decisions as GP and ECP input were suboptimal. Ways to support nurses and optimise decision-making are needed. Advance care planning can be improved, especially documentation of EOL wishes and hospitalisation orders. By

  5. Mechanism of action of recombinant acc-royalisin from royal jelly of Asian honeybee against gram-positive bacteria.

    Directory of Open Access Journals (Sweden)

    Lirong Shen

    Full Text Available The antibacterial activity of royalisin, an antimicrobial peptide from the royal jelly produced by honeybees, has been addressed extensively. However, its mechanism of action remains unclear. In this study, a recombinant royalisin, RAcc-royalisin from the royal jelly of Asian honeybee Apis cerana cerana, was expressed by fusing with glutathione S-transferase (GST in Escherichia coli BL21, isolated and purified. The agar dilution assays with inhibition zone showed that RAcc-royalisin, similar to nisin, inhibits the growth of Gram-positive bacteria. The antibacterial activity of RAcc-royalisin was associated with its concentration, and was weakened by heat treatment ranging from 55°C to 85°C for 15 min. Both RAcc-royalisin and nisin exhibited the minimum inhibitory concentrations (MIC of 62.5 µg/ml, 125 µg/ml, and 250 µg/ml against Gram-positive bacterial strains, Bacillus subtilis and Micrococcus flavus and Staphyloccocus aureus in the microplate assay, respectively. However, RAcc-royalisin did not show antimicrobial activity against tested Gram-negative bacterial and fungal strains. The antibacterial activity of RAcc-royalisin agrees well with the decrease in bacterial cell hydrophobicity, the leakage of 260-nm absorbing materials, and the observation by transmission electron microscopy, all indicating that RAcc-royalisin induced the disruption and dysfunction of cell walls and membranes. This is the first report detailing the antibacterial mechanism of royalisin against Gram-positive bacteria, and provides insight into the application of recombinant royalisin in food and pharmaceutical industries as an antimicrobial agent.

  6. ELEMENTAL FORMS OF HOSPITALITY

    OpenAIRE

    Maximiliano Emanuel Korstanje

    2010-01-01

    Modern studies emphasized on the needs of researching the hospitality as relevant aspects of tourism and hospitality fields. Anyway, these approaches are inextricably intertwined to the industry of tourism and do not take seriously the anthropological and sociological roots of hospitality. In fact, the hotel seems to be a partial sphere of hospitality at all. Under this context, the present paper explores the issue of hospitality enrooted in the political and economic indo-European principle ...

  7. Comparison of poisonings managed at military and Veterans Administration hospitals reported to Texas poison centers.

    Science.gov (United States)

    Forrester, M B

    2017-01-01

    There is little information on poisonings managed at military and Veterans Administration (VA) hospitals. This investigation described and compared poisonings reported to Texas poison centers that were managed at military and VA hospitals. Retrospective analysis of poison centre data. Cases were poisonings among patients aged 18 years or more reported to Texas poison centers during 2000-2015 where management occurred at a military or VA hospital. The distribution of exposures for various demographic and clinical factors was determined for military and veterans hospitals and comparisons were made between the two groups. There were 4353 and 1676 poisonings managed at military and VA hospitals, resepctively. Males accounted for 50.5% of the military hospital patients and 84.9% of the VA hospital patients. The mean age for military hospital patients was 31 years and for VA hospital patients was 50 years. The proportion of poisonings managed at military hospitals and VA hospitals, respectively, were intentional (70.0% vs 64.1%), particularly suspected attempted suicide (57.3% vs 47.7%), and unintentional (25.0% vs 30.5%). More than one substance was reported in 37.7% of military and 33.2% of VA hospital poisonings. The most commonly reported substance categories for poisonings managed at military and VA hospitals, respectively, were analgesics (28.4% vs 19.7%), sedatives/hypnotics/antipsychotics (24.7% vs 23.4%), antidepressants (18.7% vs 19.7%) and alcohol (11.3% vs 10.6%). A number of differences were observed between poisonings managed at military and VA hospitals. These differing patterns of poisonings may need to be taken into account in the education, prevention and treatment of poisonings at these hospitals and among the populations they serve. Copyright © 2016 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  8. Hospitable Classrooms: Biblical Hospitality and Inclusive Education

    Science.gov (United States)

    Anderson, David W.

    2011-01-01

    This paper contributes to a Christian hermeneutic of special education by suggesting the biblical concept of hospitality as a necessary characteristic of classroom and school environments in which students with disabilities and other marginalized students can be effectively incorporated into the body of the classroom. Christian hospitality, seen…

  9. Hospitality Healthscapes: The New Standard for Making Hospitals More Hospitable

    Directory of Open Access Journals (Sweden)

    Courtney Suess Raeisinafchi

    2017-06-01

    Full Text Available What comes to mind when you think of a hospital room? Stark. Sterile. Bare. Clinical. What might it mean for patients if the association with the environment shifted to something like: Comforting. Bright. Elegant. Personal?

  10. The application of hospitality elements in hospitals.

    Science.gov (United States)

    Wu, Ziqi; Robson, Stephani; Hollis, Brooke

    2013-01-01

    In the last decade, many hospital designs have taken inspiration from hotels, spurred by factors such as increased patient and family expectations and regulatory or financial incentives. Increasingly, research evidence suggests the value of enhancing the physical environment to foster healing and drive consumer decisions and perceptions of service quality. Although interest is increasing in the broader applicability of numerous hospitality concepts to the healthcare field, the focus of this article is design innovations, and the services that such innovations support, from the hospitality industry. To identify physical hotel design elements and associated operational features that have been used in the healthcare arena, a series of interviews with hospital and hotel design experts were conducted. Current examples and suggestions for future hospitality elements were also sought from the experts, academic journals, and news articles. Hospitality elements applied in existing hospitals that are addressed in this article include hotel-like rooms and decor; actual hotels incorporated into medical centers; hotel-quality food, room service, and dining facilities for families; welcoming lobbies and common spaces; hospitality-oriented customer service training; enhanced service offerings, including concierges; spas or therapy centers; hotel-style signage and way-finding tools; and entertainment features. Selected elements that have potential for future incorporation include executive lounges and/or communal lobbies with complimentary wireless Internet and refreshments, centralized controls for patients, and flexible furniture. Although the findings from this study underscore the need for more hospitality-like environments in hospitals, the investment decisions made by healthcare executives must be balanced with cost-effectiveness and the assurance that clinical excellence remains the top priority.

  11. Myocardial perfusion scintigraphy: the evidence. A consensus conference organised by the British Cardiac Society, the British Nuclear Cardiology Society and the British Nuclear Medicine Society, endorsed by the Royal College of Physicians of London and the Royal College of Radiologists

    International Nuclear Information System (INIS)

    Underwood, S.R.; Anagnostopoulos, C.; Cerqueira, M.; Ell, P.J.; Flint, E.J.; Harbinson, M.; Kelion, A.D.; Al-Mohammad, A.; Prvulovich, E.M.; Shaw, L.J.; Tweddel, A.C.

    2004-01-01

    This review summarises the evidence for the role of myocardial perfusion scintigraphy (MPS) in patients with known or suspected coronary artery disease. It is the product of a consensus conference organised by the British Cardiac Society, the British Nuclear Cardiology Society and the British Nuclear Medicine Society and is endorsed by the Royal College of Physicians of London and the Royal College of Radiologists. It was used to inform the UK National Institute of Clinical Excellence in their appraisal of MPS in patients with chest pain and myocardial infarction. MPS is a well-established, non-invasive imaging technique with a large body of evidence to support its effectiveness in the diagnosis and management of angina and myocardial infarction. It is more accurate than the exercise ECG in detecting myocardial ischaemia and it is the single most powerful technique for predicting future coronary events. The high diagnostic accuracy of MPS allows reliable risk stratification and guides the selection of patients for further interventions, such as revascularisation. This in turn allows more appropriate utilisation of resources, with the potential for both improved clinical outcomes and greater cost-effectiveness. Evidence from modelling and observational studies supports the enhanced cost-effectiveness associated with MPS use. In patients presenting with stable or acute chest pain, strategies of investigation involving MPS are more cost-effective than those not using the technique. MPS also has particular advantages over alternative techniques in the management of a number of patient subgroups, including women, the elderly and those with diabetes, and its use will have a favourable impact on cost-effectiveness in these groups. MPS is already an integral part of many clinical guidelines for the investigation and management of angina and myocardial infarction. However, the technique is underutilised in the UK, as judged by the inappropriately long waiting times and by

  12. Radiação, fotossíntese, rendimento e qualidade de frutos em macieiras 'Royal Gala' cobertas com telas antigranizo Radiation, photosynthesis, yield, and fruit quality of 'Royal Gala' apples under hail protection nets

    Directory of Open Access Journals (Sweden)

    Cassandro Vidal Talamini do Amarante

    2007-07-01

    Full Text Available O objetivo deste trabalho foi avaliar a intensidade e a qualidade da radiação solar disponibilizada às plantas e os seus impactos sobre a fotossíntese, rendimento e qualidade dos frutos, em macieiras 'Royal Gala', cobertas ou não com telas antigranizo nas cores branca e preta. A tela preta provocou redução maior na densidade de fluxo de fótons fotossinteticamente ativos acima do dossel das plantas (24,8%, em comparação à tela branca (21,2%. O interior do dossel das plantas sob tela preta recebeu menores valores de radiação ultravioleta, azul, verde, vermelho e vermelho distante, bem como da relação vermelho:vermelho distante, em relação às plantas descobertas. Estas alterações na quantidade e qualidade da luz sob tela preta aumentaram o teor de clorofila total e a área específica nas folhas, e reduziram a taxa fotossintética potencial, o peso de frutos por cm² de seção transversal de tronco e a coloração vermelha dos frutos. As telas antigranizo branca e preta reduziram a incidência de queimadura de sol, porém não tiveram efeito sobre a severidade de "russeting" e sobre o número de sementes por fruto.The objective of this work was to assess the amount and quality of the light supplied to plants, and the resulting impacts on photosynthesis, yield, and fruit quality of 'Royal Gala' apple trees uncovered or covered with white and black hail protection nets. The black net caused a higher reduction (24.8% of photosynthetic photon flux density, accumulated over the plant canopy during the day, than the white net (21.2%. The canopy internal portion of plants covered by black net received lower levels of ultraviolet, blue, green, red, and far red radiation, and light with a lower red:far red ratio, in comparison to uncovered plants; these ligth changes increased chlorophyll content and specific area of the leaves, and reduced the potential photosynthesis, the weight of fruits per cm² of trunk cross section area, and the

  13. Condições de atmosfera controlada para o armazenamento de maçãs 'Royal Gala' de diferentes tamanhos Controlled atmosphere-storage conditions for 'Royal Gala' apples of different sizes

    Directory of Open Access Journals (Sweden)

    Auri Brackmann

    2005-10-01

    Full Text Available O objetivo deste trabalho foi avaliar o efeito de condições de atmosfera controlada sobre a conservação da qualidade de maçãs 'Royal Gala' de tamanho pequeno (5-6cm de diâmetro e grande (8-9cm de diâmetro. Os frutos foram armazenados durante oito meses em atmosfera controlada, seguido de sete dias a 20°C. De acordo com os resultados obtidos, verificou-se que a condição de atmosfera controlada com 1,5kPa de O2 + 3,0kPa de CO2 permitiu melhor conservação dos frutos pequenos, por permitir menor ocorrência de degenerescência interna e elevados valores de acidez titulável. Em relação aos frutos grandes, a condição de atmosfera controlada com 1,0kPa de O2 + 3,0kPa de CO2 foi a mais adequada, pois permitiu uma maior firmeza de polpa e elevados valores de acidez titulável. Os frutos pequenos mantiveram a cor de fundo da epiderme mais verde e apresentaram menores incidências de podridões em relação aos frutos grandes.The objective of this work was to evaluate the effect of controlled atmosphere conditions on the quality of 'Royal Gala' apples of small-size (5-6cm of diameter and large-size (8-9cm of diameter. Fruit were kept during 8 months in controlled atmosphere, followed by 7 days of shelf-life at 20°C. According to the results, controlled atmosphere with 1.5kPa O2 + 3.0kPa CO2 decreased internal breakdown and maintained the highest level of tritable acidity on small size fruit. Large size fruit stored on controlled atmosphere condition with 1.0kPa O2 + 3.0kPa CO2 had higher flesh firmness and elevated tritable acidity, showing therefore better quality than fruits stored on the other evaluated conditions. Small size fruit maintained greener skin background colour and lower rot incidence than large size fruit.

  14. Use of in-patient hospital beds by people living in residential care.

    Science.gov (United States)

    Finucane, P; Wundke, R; Whitehead, C; Williamson, L; Baggoley, C

    2000-01-01

    There is concern that people living in residential care in Australia make significant and often inappropriate use of acute in-patient hospital services. To date, no factual information has been collected in Australia and its absence may allow myths and negative stereotypes to proliferate. To determine how and why people living in residential care in Australia use in-patient hospital beds. To determine the outcome of hospitalisation and functional status at 3 months following discharge. Prospective study of 184 consecutive admissions to hospital following Emergency Department (ED) attendance involving people aged over 65 years and living in residential care in southern Adelaide, South Australia. Information was obtained from the facilities' transfer letters, and where these were inadequate or absent, telephone interviews were held with residential care staff. 153 people accounted for the 184 admissions. They had a mean age of 84 years and 69% were female. 61% came from hostels and 35% from nursing homes. They had a wide range of clinical problems and twice as many were admitted to medical than to surgical units. Their mean length of hospital stay was 7.9 days, 2.3 days higher than for non-same-day patients and was higher for hostel than for nursing home residents. All but two admissions were considered unavoidable though the provision of specialised care within residential care could have prevented a further 19 (10%) admissions. 96% of admissions resulted in survival to leave hospital and in 74%, people returned directly to their place of origin. At 3 months follow-up, a further 20% of the group had died while 5% were in hospital. In all, 14% of the original group were in a different long-term care facility while 56% were living at their former residence. People living in residential care are often hospitalised because of acute illness. In the vast majority of cases hospitalisation is both appropriate and unavoidable. Most did not require prolonged hospitalisation

  15. Effect of different head and neck positions on behaviour, heart rate variability and cortisol levels in lunged Royal Dutch Sport horses

    NARCIS (Netherlands)

    Smiet, E.; Van Dierendonck, M. C.; Sleutjens, J.; Menheere, P. P C A; van Breda, E.; de Boer, D.; Back, W.; Wijnberg, I. D.; Van Der Kolk, J. H.

    2014-01-01

    Different head-and-neck positions (HNPs) are discussed in relation to potential welfare issues. To evaluate the effect on welfare, seven Royal Dutch Sport horses were studied in five predetermined HNPs: (1) unrestrained (HNP1); (2) neck raised, bridge of nose around the vertical (HNP2); (3) neck

  16. The Nuclear Department, Royal Naval School of Marine Engineering - Provision of nuclear education and training to the naval nuclear propulsion programme and beyond

    International Nuclear Information System (INIS)

    Trethewey, K.R.; Beeley, P.A.; Lockwood, R.S.; Harrop, I.

    2004-01-01

    The Nuclear Department at HMS SULTAN provides education, training and research support to the Royal Navy Nuclear Propulsion Programme, as well as a growing number of civilian programmes within the wider British nuclear industry. As an aspiring centre of excellence in nuclear engineering, the Department will play an important role as a repository of nuclear knowledge for the foreseeable future. (author)

  17. Further textile artefacts from the Royal Crypt at Prague Castle (CZ). A tablet-woven silk band and fragments of a child's funeral tunic

    Czech Academy of Sciences Publication Activity Database

    Bravermanová, M.; Březinová, Helena

    2015-01-01

    Roč. 2015, č. 57 (2015), s. 104-110 ISSN 2245-7135 R&D Projects: GA ČR(CZ) GA14-06451S Institutional support: RVO:67985912 Keywords : Royal Crypt * Anna Falcká * tablet-weaving * archaeological textile Subject RIV: AC - Archeology, Anthropology, Ethnology

  18. The effect of royal sun agaricus, agaricus brasiliensis S. Wasser et al., Extract on methyl Methanesulfonate caused genotoxicity in Drosophila melanogaster

    NARCIS (Netherlands)

    Savic, T.; Patenkovic, A.; Sokovic, M.; Glamoclija, J.; Andjelkovic, M.; Griensven, van L.J.L.D.

    2011-01-01

    The effect of culinary-medicinal Royal Sun Agaricus (Agaricus brasiliensis) hot water extract on methyl methane sulfonate (MMS) induced mutagenicity/genotoxity in Drosophila melanogaster was studied using a quick and broadly applicable in vivo assay, i.e., the wing somatic mutation and recombination

  19. Retrospective hospital based surveillance of intussusception in children in a sentinel paediatric hospital: benefits and pitfalls for use in post-marketing surveillance of rotavirus vaccines.

    Science.gov (United States)

    Lloyd-Johnsen, C; Justice, F; Donath, S; Bines, J E

    2012-04-27

    Evaluation of the safety of rotavirus vaccines, particularly with respect to the risk of intussusception, is recommended for countries planning to introduce rotavirus vaccines into the National Immunisation Program. However, as prospective studies are costly, require time to conduct and may be difficult to perform in some settings, retrospective hospital based surveillance at sentinel sites has been suggested as an option for surveillance for intussusception following introduction of rotavirus vaccines. To assess the value of retrospective hospital based surveillance to describe clinical and epidemiological features of intussusception in children aged <24 months and to investigate any temporal association between receipt of a rotavirus vaccine and intussusception. A retrospective chart review of all patients diagnosed with intussusception at Royal Children's Hospital, Melbourne, Australia over an 8-year period including before and after rotavirus vaccine introduction into the National Immunisation Program, was conducted using patients identified by a medical record database (ICD-10-CM 56.1). Patient profile, clinical presentation, treatment and outcome were analysed along with records of immunisation status obtained using the Australian Childhood Immunisation Register. A 9% misclassification rate of discharge diagnosis of intussusception was identified on critical chart review. The incidence rate of intussusception at the Royal Children's Hospital over the study period was 1.91 per 10,000 infants <24 months (95% CI 1.65-2.20). Intestinal resection was required in 6.5% of infants (95% CI 3.6%, 11.0%). Intussusception occurred within 30 days after vaccination in 2 of 27 patients who had received at least 1 dose of a rotavirus vaccine. Valuable data on the incidence, clinical presentation and treatment outcomes of intussusception can be obtained from data retrieved from hospital medical records in a sentinel paediatric hospital using standardised methodology. However

  20. Community Hospital Telehealth Consortium

    National Research Council Canada - National Science Library

    Williams, Elton

    2004-01-01

    The Community Hospital Telehealth Consortium is a unique, forward-thinking, community-based healthcare service project organized around 5 not-for-profit community hospitals located throughout Louisiana and Mississippi...

  1. The interstices of hospitality

    African Journals Online (AJOL)

    jane.b

    School of Hospitality and Tourism, Anhembi Morumbi University, São Paulo, Brazil ... aspects of hospitality, and the approach of the social sciences, which study the dynamics of ..... in the virtual media, the ritual always begins with an invitation.

  2. Community Hospital Telehealth Consortium

    National Research Council Canada - National Science Library

    Williams, Elton

    2003-01-01

    The Community Hospital Telehealth Consortium is a unique, forward-thinking, community-based healthcare service project organized around 5 not-for-profit community hospitals located throughout Louisiana and Mississippi...

  3. Unplanned Hospital Visits - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — Unplanned Hospital Visits – national data. This data set includes national-level data for the hospital return days (or excess days in acute care) measures, the...

  4. The Hospitable Meal Model

    DEFF Research Database (Denmark)

    Justesen, Lise; Overgaard, Svend Skafte

    2017-01-01

    This article presents an analytical model that aims to conceptualize how meal experiences are framed when taking into account a dynamic understanding of hospitality: the meal model is named The Hospitable Meal Model. The idea behind The Hospitable Meal Model is to present a conceptual model...... that can serve as a frame for developing hospitable meal competencies among professionals working within the area of institutional foodservices as well as a conceptual model for analysing meal experiences. The Hospitable Meal Model transcends and transforms existing meal models by presenting a more open......-ended approach towards meal experiences. The underlying purpose of The Hospitable Meal Model is to provide the basis for creating value for the individuals involved in institutional meal services. The Hospitable Meal Model was developed on the basis of an empirical study on hospital meal experiences explored...

  5. Structural Measures - Hospital

    Data.gov (United States)

    U.S. Department of Health & Human Services — A list of hospitals and the structural measures they report. A structural measure reflects the environment in which hospitals care for patients, for example, whether...

  6. Hospital Compare - Archived Data

    Data.gov (United States)

    U.S. Department of Health & Human Services — Hospital Compare is a consumer-oriented website that provides information on how well hospitals provide recommended care to their patients. This information can help...

  7. Research in Hospitality Management

    African Journals Online (AJOL)

    Research in Hospitality Management (RHM) is a peer-reviewed journal ... to the quintessential managerial areas of Finance, Human Resources, Operations, ... competency and career development of hospitality management students · EMAIL ...

  8. Community Hospital Telehealth Consortium

    National Research Council Canada - National Science Library

    Williams, Jr, Elton L

    2007-01-01

    The Community Hospital Telehealth Consortium is a unique, forward-thinking, community-based healthcare service project organized around 5 not-for-profit community hospitals located throughout Louisiana and Mississippi...

  9. Effects of Royal Jelly and Bee Pollen on the Growth of Selected Probiotic Bacteria (Bf. animalis Spp. Lactis, L. acidophilus and L. casei

    Directory of Open Access Journals (Sweden)

    Guldas Metin

    2016-12-01

    Full Text Available In this research article, the effects of bee pollen and royal jelly on the selected probiotic bacteria, as growth factors, were investigated. The probiotic cultures were activated in MRS broth at 37°C. Then, bee pollen and royal jelly (10 mg/100 μL, 25 mg/250 μL, 50 mg/500 μL, 75 mg/750 μL, and 100 mg/1000 μL were added on the probiotic cultures in MRS broth and sampled at 0, 24, and 48 hours of incubation. The medias used for enumeration of the probiotic cultures were RCA (Reinforced Clostridial Agar for Bf. animalis spp. lactis, MRS (deMann, Rogosa and Sharpe Agar with D-sorbitol for Lb. acidophilus and MRS-Vancomycine Agar for Lb. casei. The lactic acid production by Lb. acidophilus, Lb. casei, and Bf. animalis spp. lactis, and acetic acid production by Bf. animalis spp. lactis, were determined to compare the bacterial proliferation. The probiotic cultures were mainly affected by the bee pollen and royal jelly during the first 24 hours. The changes observed in the number of probiotic counts between 24 and 48 hours were not significant, statistically (P<0.05. Generally, the probiotic bacterial counts increased parallel to the concentration of bee pollen or royal jelly up to 75mg, and remained unchanged above this concentration. In terms of lactic acid production and bacterial growth, the most significant growth was observed on Lb. acidophilus when bee pollen or royal jelly was added.

  10. UPLC-PDA quantification of chemical constituents of two different varieties (golden and royal) of apple leaves and their antioxidant activity.

    Science.gov (United States)

    Walia, Mayanka; Kumar, Shiv; Agnihotri, Vijai K

    2016-03-30

    Malus domestica is the most widely cultivated fruit tree and is well known for its therapeutic value. Apple leaves are known to contain phenolic compounds but the nature of these has not been explored to the same extent as in apple fruit. A simple, rapid and sensitive ultra-performance liquid chromatography-diode array detection (UPLC-DAD) quantification method has been developed. Total polyphenol and flavonoid contents, as well as the antioxidant activity of golden and royal apple leaves were evaluated. Four compounds, namely rutin, 3-hydroxyphloridzin, phloridzin and quercetin-3-O-arabinoside were identified by UPLC. The separation was achieved in less than 7 min. Total polyphenol and flavonoid contents were found to be slightly higher in apple golden variety than royal variety. The IC50 values determined by the DPPH assay were 49.94 µg mL(-1) for golden apple leaves and 43.89 µg mL(-1) for royal apple leaves. IC50 values determined by the ABTS assay were 47.10 and 66.53 µg mL(-1) for golden and royal apple leaves, respectively. Antioxidant activity was determined as 24.45 and 21.15 mg ascorbic acid g(-1) for golden and royal apple leaves, respectively, by using the FRAP assay. This study showed that apple leaves (both varieties) contain considerable amounts of polyphenols and flavonoids and are also a promising source of phloridzin. © 2015 Society of Chemical Industry.

  11. Investigating the Antioxidant Properties of Royal Jelly and Vitamin C on Enzymes, Histomorphometric and Liver Cells Apoptosis in Mice Suffering Hemolytic Anemia

    Directory of Open Access Journals (Sweden)

    Hojat Anbara

    2016-09-01

    Full Text Available Background & Objective: Hemolytic anemia induced by phenylhydrazine (PHZ as a hemolytic composition can change the function and structure of liver. Therefore, the present study attempts to evaluate the protective effects of vitamin C and royal jelly co-administration against the oxidative damages and liver apoptosis induced by hemolytic anemia in adult mice. Materials & Methods: 32 adult male mice were divided equally and randomly into four groups. The first group received normal saline with a dose of 0.1 ml, IP. The second group received a dose of vitamin C (250 kg/mg, IP along with 100 kg/mg dose of royal jelly administered orally. The third group was administered with 6 mg/100 gr, IP phenylhydrazine in 48 hour intervals. Finally, the fourth group received vitamin C and royal jelly in the doses similar to the first three groups along with phenylhydrazine with the same doses of previous groups. After 35 days, the serum and testis samples were taken and were used for serum analysis and histochemical and histomorphometric studies. Results: Phenylhydrazine increased the level of serum concentration of aspartate transaminase, alkaline phosphatase, alanine transaminase, malondialdehyde and lactate dehydrogenase and decreased the superoxide dismutase along with the total antioxidant capacity and serum albumin. Moreover, phenylhydrazine increased the apoptosis, the number of kupffer cells and the diameter of hepatocytes. Prescribing the royal jelly with vitamin C improved the changes of abovementioned parameters significantly. Conclusion: Royal jelly with vitamin C is an antioxidant with the potential properties in preventing the oxidative damages and apoptosis induced by phenylhydrazine-induced hemolytic anemia in mouse liver.

  12. Summary document on the proposed decision by the Environment Agency on the application by Devonport Royal Dockyard Limited (DML) to dispose of radioactive wastes from Devonport Royal Dockyard Plymouth. Radioactive Substances Act 1993

    International Nuclear Information System (INIS)

    2001-11-01

    The Environment Agency (the Agency) has reached a proposed decision on the application from Devonport Royal Dockyard Limited (known as DML) to dispose of radioactive waste from its premises in Plymouth. After careful consideration of the application, which included advice from health and radiological protection experts and an extended public consultation, the Agency now proposes to grant DML a new authorisation containing a series of stringent conditions to protect people and the environment. This proposed decision is now being submitted to the Secretary of State for Environment, Food and Rural Affairs and the Secretary of State for Health. This will enable the ministers to decide whether they wish to exercise their powers in relation to DML's application. The Agency is satisfied that: The contents of the proposed authorisation are consistent with European and UK law. International treaty obligations, government policy objectives and protection of public health, the food chain and the environment; The issuing of the new authorisation to DML would not have a significant environmental impact and the health risks from the discharges at the proposed limits are not significant in radiological terms; The proposed authorisation reflects the best advice on the risk to humans from low level radiation; The programme of improvements that the operator is required to carry out, together with new generally lower discharge limits will provide potentially significant environmental improvements; The proposed integrated authorisations will provide a better basis for regulation than the existing authorisations. (author)

  13. Job sharing at a children's hospital: evaluation by medical staff.

    Science.gov (United States)

    Valentine, J P; Martin, C J

    1996-01-13

    To evaluate job sharing for registrars at Princess Margaret Hospital for Children, Perth, by seeking responses from members of the relevant medical teams. A questionnaire was sent to all 126 medical staff within the hospital (and three managers in medical administration) asking their views on job sharing for registrars. Whether job sharing should continue, who should do it, at what stage of training, and the effects on patient care. Among the 77 respondents (60%) there was broad support for the continuation of job sharing at the hospital: only 5 of 37 consultants and 2 of 19 non-job sharing registrars rejected the idea (with a further 4 consultants uncertain). 43% Of the consultants who had worked with job sharing registrars thought continuity of care was adversely affected. The committee for physician training of the Royal Australasian College of Physicians emphasises that advanced training should be flexible, with a wide range of opportunities for individuals to plan an appropriate training programme in line with their personal goals. This study has shown that job sharing for registrars at Princess Margaret Hospital for Children allows this choice. Action on concerns over any adverse effects on patient care should resolve any persisting disquiet.

  14. Communication between hospitals and isolated aboriginal community health clinics.

    Science.gov (United States)

    Mackenzie, G; Currie, B J

    1999-04-01

    This study described the communication dynamics, identified problems and recommended changes to improve patient follow-up and communication between Royal Darwin Hospital (RDH) and isolated Aboriginal community health clinics (CHC) in the Northern Territory (NT). In 1995, staff interviews were conducted and an audit of isolated Aboriginal patients' RDH discharge summaries (DS). Eighteen per cent of RDH DSs never arrived in CHCs. DSs were often prepared late and more likely to be in CHC records if written on time and if the referral source was specified. Interviews revealed discontent between CHCs and RDH regarding: communication, DS documentation, the supply of discharge medication, as well as different hospital and community perceptions of Aboriginies' reliability to carry a DS and CHC desire for patients to be given DSs at discharge. Aboriginal patients should be given a DS at discharge and resident medical officers should be educated as to the function and importance of the DS. In 18 months following this study, RDH appointed unit-based Aboriginal health workers and a policy was produced for written communication between hospital and CHCs, as well as a discharge planning manual for Aboriginal communities. Projects investigating communication between hospitals and isolated Aboriginal clinics and patient follow-up may result in significant policy changes concerning these processes.

  15. A new approach to enhance reproductive performance in sheep using royal jelly in comparison with equine chorionic gonadotropin.

    Science.gov (United States)

    Husein, M Q; Haddad, S G

    2006-06-01

    The objective was to compare the effects of royal jelly (RJ) and eCG treatments on reproductive performance of ewes synchronized using intravaginal progesterone-releasing devices. Forty-two cycling Awassi ewes were treated intramuscularly (i.m.) with 15 mg PGF2alpha. On the following day, all ewes were administered with CIDR-G for 12 days and were randomly allocated to three (RJ, eCG and control) groups of 14 ewes each. Ewes in the RJ-treated group received daily i.m. treatments of 400mg RJ during the period of CIDR-treatment. Each ewe in the eCG-treated group received an i.m. treatment of 500 IU eCG at the time of CIDR-G removal (day 0) and no further treatment was given to ewes in the control group. Ewes were exposed to four fertile rams for 72 h, from the time of CIDR-G removal, and checked for breeding marks at 6-h intervals. Blood samples were collected from day -13 until day 0 and thereafter until day 19 for progesterone analysis. Royal jelly treatment resulted in a greater rate of decline and lower (Pprogesterone concentrations between days -10 and 0 than eCG-treated and control ewes. Expression of estrus was similar among the three groups and intervals to onset of estrus were shorter (P<0.01) in RJ-treated (31.3h) and eCG-treated (29.8h) than control (41.3h) ewes. First-cycle pregnancy and lambing rates were greater (P<0.05) in RJ-treated (71.4 and 71.4%) and eCG-treated (85.7 and 78.6%) than in control (42.9 and 35.7%) ewes, respectively. Results demonstrate that the treatments of RJ and eCG in conjunction with CIDR-G were similarly effective in induction of estrus and improvement of pregnancy and lambing rates.

  16. Creditors and Converts: The Impact of Royal Policy and Corporate Debt on the Collective Identity of Majorcan Conversos after 1391

    Directory of Open Access Journals (Sweden)

    Oeltjen, Natalie

    2013-06-01

    Full Text Available Royal correspondence of the Kingdom of Majorca reveals that “external” economic factors and royal policies forced the first generations of 1391 conversos to remain a distinct social group. Not long after the anti-Jewish violence and mass conversions of 1391, the conversos of Majorca granted a percentage of their assets to King Joan I. At the same time, the conversos and surviving Jews had to repay the creditors of the former aljama, which had been dissolved following the attack against the Jewish quarter. These two collective financial obligations required the conversos to organize themselves as a group, following the precedent of the aljama, with elected leaders who organized an internal tax collection in order to pay these debts, and who lobbied on behalf of the conversos before the king and before their creditors. This administrative structure set the foundation for the converso confraternity of Sant Miquel, founded in 1404.Un examen detallado de la correspondencia real relativa a Mallorca muestra que factores económicos «externos» y directivas políticas reales obligaron a la primera generación de conversos de 1391 a permanecer como grupo social distintivo. Poco después de producirse la violencia anti-judía y las conversiones masivas de 1391, los conversos de Mallorca tuvieron que otorgar un porcentaje de sus propiedades al rey Juan I. Al mismo tiempo, conversos y judíos supervivientes debían seguir pagando los «censalers» de la aljama de judíos que había sido disuelta tras el ataque en 1391 contra la judería. Estas dos obligaciones financieras colectivas obligaron a los conversos a organizarse, siguiendo el precedente de la aljama, como grupo con líderes elegidos que administraron la colección fiscal interna a fin de pagar esas deudas, e interviniendo a favor de los conversos ante el rey y sus acreedores. Esta estructura administrativa puso los fundamentos de la cofradía conversa de Sant Miquel, establecida en 1404.

  17. Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the management of schizophrenia and related disorders.

    Science.gov (United States)

    Galletly, Cherrie; Castle, David; Dark, Frances; Humberstone, Verity; Jablensky, Assen; Killackey, Eóin; Kulkarni, Jayashri; McGorry, Patrick; Nielssen, Olav; Tran, Nga

    2016-05-01

    This guideline provides recommendations for the clinical management of schizophrenia and related disorders for health professionals working in Australia and New Zealand. It aims to encourage all clinicians to adopt best practice principles. The recommendations represent the consensus of a group of Australian and New Zealand experts in the management of schizophrenia and related disorders. This guideline includes the management of ultra-high risk syndromes, first-episode psychoses and prolonged psychoses, including psychoses associated with substance use. It takes a holistic approach, addressing all aspects of the care of people with schizophrenia and related disorders, not only correct diagnosis and symptom relief but also optimal recovery of social function. The writing group planned the scope and individual members drafted sections according to their area of interest and expertise, with reference to existing systematic reviews and informal literature reviews undertaken for this guideline. In addition, experts in specific areas contributed to the relevant sections. All members of the writing group reviewed the entire document. The writing group also considered relevant international clinical practice guidelines. Evidence-based recommendations were formulated when the writing group judged that there was sufficient evidence on a topic. Where evidence was weak or lacking, consensus-based recommendations were formulated. Consensus-based recommendations are based on the consensus of a group of experts in the field and are informed by their agreement as a group, according to their collective clinical and research knowledge and experience. Key considerations were selected and reviewed by the writing group. To encourage wide community participation, the Royal Australian and New Zealand College of Psychiatrists invited review by its committees and members, an expert advisory committee and key stakeholders including professional bodies and special interest groups. The

  18. Medicare Hospital Spending Per Patient - Hospital

    Data.gov (United States)

    U.S. Department of Health & Human Services — The "Medicare hospital spending per patient (Medicare Spending per Beneficiary)" measure shows whether Medicare spends more, less or about the same per Medicare...

  19. Hospitality and prosumption | Ritzer | Research in Hospitality ...

    African Journals Online (AJOL)

    Research in Hospitality Management. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 5, No 1 (2015) >. Log in or Register to get access to full text downloads.

  20. Energy expenditure, nutritional status, body composition and physical fitness of Royal Marines during a 6-month operational deployment in Afghanistan.

    Science.gov (United States)

    Fallowfield, Joanne L; Delves, Simon K; Hill, Neil E; Cobley, Rosalyn; Brown, Pieter; Lanham-New, Susan A; Frost, Gary; Brett, Stephen J; Murphy, Kevin G; Montain, Scott J; Nicholson, Christopher; Stacey, Michael; Ardley, Christian; Shaw, Anneliese; Bentley, Conor; Wilson, Duncan R; Allsopp, Adrian J

    2014-09-14

    Understanding the nutritional demands on serving military personnel is critical to inform training schedules and dietary provision. Troops deployed to Afghanistan face austere living and working environments. Observations from the military and those reported in the British and US media indicated possible physical degradation of personnel deployed to Afghanistan. Therefore, the present study aimed to investigate the changes in body composition and nutritional status of military personnel deployed to Afghanistan and how these were related to physical fitness. In a cohort of British Royal Marines (n 249) deployed to Afghanistan for 6 months, body size and body composition were estimated from body mass, height, girth and skinfold measurements. Energy intake (EI) was estimated from food diaries and energy expenditure measured using the doubly labelled water method in a representative subgroup. Strength and aerobic fitness were assessed. The mean body mass of volunteers decreased over the first half of the deployment ( - 4·6 (sd 3·7) %), predominately reflecting fat loss. Body mass partially recovered (mean +2·2 (sd 2·9) %) between the mid- and post-deployment periods (Penergy expenditure (mean 15 167 (sd 1883) kJ) measured in a subgroup of volunteers. However, despite the body mass loss, aerobic fitness and strength were well maintained. Nutritional provision for British military personnel in Afghanistan appeared sufficient to maintain physical capability and micronutrient status, but providing appropriate nutrition in harsh operational environments must remain a priority.

  1. Work related mortality among merchant seafarers employed in UK Royal Fleet Auxillary shipping from 1976 to 2005.

    Science.gov (United States)

    Roberts, Stephen E; Marlow, Peter B

    2006-01-01

    Over 2300 merchant seafarers are currently employed on board UK Royal Fleet Auxiliary (RFA) ships. However, little is known about work related mortality among these seafarers, and whether it is lower than among seafarers in merchant fleets. To establish the causes and circumstances of all work related deaths among seafarers who were employed in RFA ships from 1976 to 2005, to compare mortality rates with those in other merchant fleets, and to identify implications for maritime health. A population based study of work related mortality over 30 years. A total of 60 deaths among seafarers in RFA ships were caused by disease (30), accidents (19), suicide (6), homicide (one), and inconclusive causes (4). Six of the 19 fatal accidents were directly related to work duties (occupational accidents), 12 occurred during off-duty time and one resulted from a shipping disaster. The fatal accident rate was about one half, and the fatal work related accident rate was about one quarter, of corresponding rates in UK merchant shipping from 1976-2002; and they were much lower than those in merchant fleets internationally. The fatal accident rate in RFA shipping also fell by about 80% over the 30 year study period. The lower fatal accident rates in RFA shipping, particularly for work related accidents, presumably reflect a lower incidence of hazardous working practices, arising from better training and career pathways for seafarers in RFA shipping, as well as better maintained ships with higher manning levels than in merchant shipping.

  2. Protective Effect of Royal Jelly against Phenylhydrazine-induced Histological Injuries of Small Intestine of Mice: Morphometric Analyses

    Directory of Open Access Journals (Sweden)

    Hojat Anbara

    2016-01-01

    Full Text Available Background and Objectives: Phenylhydrazine (PHZ, as a known hemolytic agent, causes toxicity in different tissues at various levels. The aim of the current study was to examine the possible protective effects of royal jelly (RJ against PHZ-induced histological injuries of small intestine in mice.   Methods: In this experimental study, adult male mice were randomly divided into four groups of 8 mice each. PHZ was administered intraperitoneally to two groups of mice (at a dose of 60mg/kg every 48 hours for 35 days. One of the groups received RJ (100mg/kg orally 4 hours before PHZ administration. The third group only received RJ, and the forth group was considered as control. Twenty-four hours after the last treatment, different segments of small intestine were dissected out, then histological sections were prepared and quantitative morphometric assessments were performed. To compare the groups, one-way ANOVA and multiple comparative Tukey tests were used. The significance level was considered to be p<0.05.   Results: In this study, PHZ caused significant decreases in depth of duodenal crypts, distribution rate of the goblet cells in ileal villi, width of duodenal and jejunal villi, and height of villi in all three segments of small intestine. Co-administration of RJ partially improved the changes in the above parameters.   Conclusion: From results of this study, it seems that RJ as a free radical scavenger could reduce PHZ-induced intestinal toxicity in mouse.

  3. Ephemeroptera, Plecoptera, and Trichoptera on Isle Royale National Park, USA, compared to mainland species pool and size distribution.

    Science.gov (United States)

    DeWalt, R Edward; South, Eric J

    2015-01-01

    Extensive sampling for aquatic insects was conducted in the orders Ephemeroptera (mayflies), Plecoptera (stoneflies), and Trichoptera (caddisflies) (EPT) of Isle Royale National Park (ISRO), Michigan, United States of America, during summer 2013. The island was ice covered until 8,000 to 10,000 years ago and is isolated by 22-70 km distance from the mainland. Two hypotheses were examined: that ISRO EPT richness would be much reduced from the mainland, and that the species colonizing ISRO would be of smaller size than mainland, adults presumably using updrafts to bridge the distance from mainland sources. Data sets were developed for known mainland EPT species and size for those species. The first hypothesis was confirmed with the mainland species pool consisting of 417 EPT, while ISRO is known to support 73 species. Richness of EPT is directly related to the number of specimens examined. Small streams supported five EPT species, while 15-25 species were found in larger streams. Lakeshores had intermediate diversity. The second hypothesis was substantiated for stoneflies, but not for mayflies or caddisflies. Stoneflies apparently are poorer fliers than either of the other two orders.

  4. The Royal Australian College of Radiologists (RACR) survey of reactions to intravenous ionic and non-ionic contrast media

    International Nuclear Information System (INIS)

    Palmer, J.F.

    1989-01-01

    The Royal Australian College of Radiologists (RACR) expressed concern as to medico-legal implications of the continued use of conventional ionic contrast media in view of the availability of the new low-osmolar media. The new agents had demonstrated significant advantages and it was anticipated that their use would be associated with a lower incidence of undesirable reactions and deaths. However, these new media are significantly more expensive than conventional ionic media and complete changes to these agents has considerable implications for health budgets. Since it was the view of the RACR that there was insufficient information available of the incidence of reactions in clinical use to justify a complete change, a prospective survey of reations to intravenous contrast media injections was initiated. Particpants were issued a simple form, which required for each patient a record of the presence or absence of risk factors, wether ionic or non-ionic contrast media were used, and of the severity of eventual reactions. The results of about 170.000 patients were reported. The survey demonstrated the relative safety of non-ionic media for intravenous use. Despite the relative high cost of these media the continued use of conventional ionic media will become increasingly difficult to justify. (H.W.). 9 refs.; 4 tabs

  5. The Green Electricity: The Potential of Using Solar Pv Panel for The Royal Malaysian Police (RMP Building

    Directory of Open Access Journals (Sweden)

    Md Yasin Md Hafiz

    2016-01-01

    Full Text Available As the year 2020 approaches, Malaysia aims to be self-sufficient and independence in finding resources to fuel its development, especially in energy sector. To achieve this aims, Malaysia need to strengthen its energy sustainability aspect and have a clear foresight in handling energy security issue. In coming decades, energy crisis due the existence of the significant energy threat may cause power interruptions and lead to many interrelated problems, especially safety and security issues. Issues such as unstable political and economic situation in Middle East country, Spratly issue, South China Sea territorial issue, war and terrorist may lead to unstable safety and security environment for Malaysia. The most significant organization to keep the safety and security of Malaysia is The Royal Malaysian Police (RMP. However, at the moment, this organization is fully-reliant on centralized electricity supply that may interrupt due to the future energy threat. Therefore, it is important for this organization to have an independence and self-sufficient electricity supply in order to remain their operation in any circumstances .The solar energy, through Photovoltaic (PV panel, has been identified as the significant resources to achieve this purposes. With constant solar irradiance, Malaysia has great potential in solar energy harvesting. The energy is clean, environmental-friendly, reliable and readily-accessible throughout the year. This paper will review the potential of green electricity through solar PV in being the power supply for RMP in order to maintain the security and safety of Malaysia

  6. Histological and Biochemical Analyses of the Effects of Royal Jelly and Vitamin C against Phenylhydrazine-Induced Cardiotoxicity in Mice

    Directory of Open Access Journals (Sweden)

    Hojat Anbara

    2017-10-01

    Full Text Available Abstract Background: Phenylhydrazine (PHZ as a strong oxidant agent causes variety of toxic effects including alterations in the biochemical and cardiac tissue. The aim of the present study was to investigate the effects of royal jelly (RJ and vitamin C (vit C against PHZ-induced cardiotoxicity in mice. Materials and Methods: Adult male mice were randomly assigned to eight groups of eight mice each. PHZ was administered to four groups of mice at a dose of 60 mg/kg per 48 hours intraperitoneally for 35 days. Three of these groups received vit C (250 mg/kg per day intraperitoneally, RJ (100 mg/kg per day orally and vit C+RJ with same doses four hours before PHZ administration, respectively. A vehicle-treated control group and vit C, RJ and vit C+RJ control groups were also included. Results: RJ and vit C significantly decreased (p< 0.05 the serum level of malondialdehyde and creatine kinase (CK-BM that had been increased by PHZ. Also, RJ and vit C increased the total antioxidant capacity and supraxoid dismutase serum that had been decreased by induced PHZ. Moreover, RJ and vit C could improve the tissue damages induced by PHZ such as diffused edema, hemorrhage, congestion, hyaline exudates, necrosis and also fibrosis tissue in heart tissue. Conclusion: It seems that Vit C and RJ can minimize PHZ-induced cardiotoxicity in mouse through oxidative reactions inhibition.

  7. Optical Coherence Tomography of Retinal Degeneration in Royal College of Surgeons Rats and Its Correlation with Morphology and Electroretinography

    Science.gov (United States)

    Yamauchi, Kodai; Mounai, Natsuki; Tanabu, Reiko; Nakazawa, Mitsuru

    2016-01-01

    Purpose To evaluate the correlation between optical coherence tomography (OCT) and the histological, ultrastructural and electroretinography (ERG) findings of retinal degeneration in Royal College of Surgeons (RCS-/-) rats. Materials and Methods Using OCT, we qualitatively and quantitatively observed the continual retinal degeneration in RCS-/- rats, from postnatal (PN) day 17 until PN day 111. These findings were compared with the corresponding histological, electron microscopic, and ERG findings. We also compared them to OCT findings in wild type RCS+/+ rats, which were used as controls. Results After PN day 17, the hyperreflective band at the apical side of the photoreceptor layer became blurred. The inner segment (IS) ellipsoid zone then became obscured, and the photoreceptor IS and outer segment (OS) layers became diffusely hyperreflective after PN day 21. These changes correlated with histological and electron microscopic findings showing extracellular lamellar material that accumulated in the photoreceptor OS layer. After PN day 26, the outer nuclear layer became significantly thinner (P RCS-/- and RCS+/+ rats. Conclusion Our results suggest that OCT demonstrates histologically validated photoreceptor degeneration in RCS rats, and that OCT findings partly correlate with ERG findings. We propose that OCT is a less invasive and useful method for evaluating photoreceptor degeneration in animal models of retinitis pigmentosa. PMID:27644042

  8. Management of Information and Infrastructure of Indigenous Community at Royal Belum State Park Using Geographical Information System: A Conceptual Design

    Directory of Open Access Journals (Sweden)

    Othman Zainon

    2015-06-01

    Full Text Available Abstract. Nowadays, an integrated location, descriptive inventory data and geographical information are required for a better decision making in Indigenous community management activities. The management system can improve productivity and to save time, money and man power. Conventional maps and Indigenous inventories on papers or spread sheet are lack of meeting these requirements which are not static and subjected to change rapidly. The Geographic Information Systems (GIS and Database Management (DBM System are capabilities and confined in manipulation of location and descriptive data, respectively. A GIS system is chosen in Management Information and Infrastructure of Indigenous Communities because its meets all the requirements that can help the authorities to managed the community. GIS able to manipulate location and descriptive data as well as the relationships between them are dynamic. This paper will discussed briefly the conceptual design of GIS activities and Indigenous community in Royal Belum State Park, Malaysia, then terminology and theoretical concepts of GIS, Indigenous community management and the link between them are reviewed. Keywords: Management, information, infrastructure, conceptual design, Indigenous community

  9. Management of Information and Infrastructure of Indigenous Community at Royal Belum State Park Using Geographical Information System: A Conceptual Design

    Directory of Open Access Journals (Sweden)

    Othman Zainon

    2015-07-01

    Full Text Available Abstract. Nowadays, an integrated location, descriptive inventory data and geographical information are required for a better decision making in Indigenous community management activities. The management system can improve productivity and to save time, money and man power. Conventional maps and Indigenous inventories on papers or spread sheet are lack of meeting these requirements which are not static and subjected to change rapidly. The Geographic Information Systems (GIS and Database Management (DBM System are capabilities and confined in manipulation of location and descriptive data, respectively. A GIS system is chosen in Management Information and Infrastructure of Indigenous Communities because its meets all the requirements that can help the authorities to managed the community. GIS able to manipulate location and descriptive data as well as the relationships between them are dynamic. This paper will discussed briefly the conceptual design of GIS activities and Indigenous community in Royal Belum State Park, Malaysia, then terminology and theoretical concepts of GIS, Indigenous community management and the link between them are reviewed.Keywords:  Management, information, infrastructure, conceptual design, Indigenous community 

  10. Shock-absorbing insoles reduce the incidence of lower limb overuse injuries sustained during Royal Marine training.

    Science.gov (United States)

    House, Carol; Reece, Allyson; Roiz de Sa, Dan

    2013-06-01

    This study was undertaken to determine whether the incidence of lower limb overuse injuries (LLOIs) sustained during Royal Marine training could be reduced by issuing the recruits with shock-absorbing insoles (SAIs) to wear in their military boots. This was a retrospective longitudinal trial conducted in two phases. Injury data from 1,416 recruits issued with standard Saran insoles and 1,338 recruits issued with SAI were compared. The recruits in the two groups were of similar height, body mass, and aerobic fitness and followed the same training course. The incidence of LLOI sustained by the recruits was lower (p tibial periostitis, tenosynovitis of foot, achilles tendonopathy, other tendonopathy and anterior knee pain were lower (p Tibial stress fracture incidence was lower (p < 0.05) in the SAI Group but metatarsal and femoral stress fracture incidences were the same for the two insole groups. Thus, issuing SAIs to military recruits undertaking a sustained, arduous physical training program with a high incidence of LLOI would provide a beneficial reduction in the incidence of LLOI. Reprint & Copyright © 2013 Association of Military Surgeons of the U.S.

  11. The Evolving Role of Botanical Gardens and Natural Areas: A Floristic Case Study from Royal Botanical Gardens, Canada

    Institute of Scientific and Technical Information of China (English)

    David A. GALBRAITH; Natalie E. IWANYCKI; Brechann V. McGOEY; Jamie McGREGOR; James S. PRINGLE; Carl J. ROTHFELS; Tyler W. SMITH

    2011-01-01

    As leaders calling for the conservation of the world's plants, botanical gardens protect plants within living collections. Many also study, manage and restore plants in natural habitats. Royal Botanical Gardens (Ontario,Canada) has integrated both horticultural and natural heritage in its mission for decades. Envisioned by municipal leaders in the 1920s as a combination of nature sanctuaries and civic gardens, RBG now includes forests, wetlands and other habitats, gardens and built spaces. Today RBG is Canada's largest botanical garden on the basis of area.In the 1950s RBG began to inventory plant diversity. The checklist of spontaneous vascular plants now exceeds 1 170 species, of which 752 are native. This is 37% of Ontario's native vascular plants and 19% of the native vascular flora of Canada. The RBG nature sanctuaries are among the richest locations in Canada for species-level diversity.We examine the history of fioristic exploration within RBG and compare plant species-area relationships among protected natural areas in Ontario. This comparison supports the contention that the nature sanctuaries, and in particular Cootes Paradise, could be considered an important area for plants in Canada, and relative to the nation's flora, a biodiversity hotspot. The fact that a candidate vascular plant hotspot for Canada lies within a major botanical garden presents opportunities for raising public awareness of the importance of plant diversity, as well as focusing attention on the scientific and conservation biology needs of communities and individual species in this area.

  12. The consumption of propolis and royal jelly in preventing upper respiratory tract infections and as dietary supplementation in children

    Directory of Open Access Journals (Sweden)

    Sevda Yuksel

    2016-09-01

    Full Text Available Propolis and royal jelly (RJ, two important honeybee products, have been used commonly all over the World as traditional and ethnopharmacological nutrients since ancient times. Both of them have a lot of active ingredients, which are known to be effective for several medical conditions. In this article, medical databases were searched for the usage of RJ and propolis in upper respiratory tract infections (URTI and as a dietary supplementation, together and separately. 10-hydroxy-2-decenoic acid (10-HDA is the most prominent active compound showing antimicrobial effect within RJ. Caffeic acid phenethyl ester (CAPE is the most famous one that shows antimicrobial and anti-inflammatory effect within propolis. When compared with propolis, RJ was found to have richer content for all three main nutrients; proteins, carbohydrates, and lipids. More clinical, experimental, and basic studies are needed to find out the best-standardized mixture to cope with URTI in which RJ and propolis will be main ingredients in addition to the other secondary compounds that have health-beneficial effects. [J Complement Med Res 2016; 5(3.000: 308-311

  13. Royal jelly protects against ultraviolet B-induced photoaging in human skin fibroblasts via enhancing collagen production.

    Science.gov (United States)

    Park, Hye Min; Hwang, Eunson; Lee, Kwang Gill; Han, Sang-Mi; Cho, Yunhi; Kim, Sun Yeou

    2011-09-01

    Royal jelly (RJ) is a honeybee product containing proteins, carbohydrates, fats, free amino acids, vitamins, and minerals. As its principal unsaturated fatty acid, RJ contains 10-hydroxy-2-decenoic acid (10-HDA), which may have antitumor and antibacterial activity and a capacity to stimulate collagen production. RJ has attracted interest in various parts of the world for its pharmacological properties. However, the effects of RJ on ultraviolet (UV)-induced photoaging of the skin have not been reported. In this study we measured the 10-HDA content of RJ by high-performance liquid chromatography and tested the effects of RJ on UVB-induced skin photoaging in normal human dermal fibroblasts. The effects of RJ and 10-HDA on UVB-induced photoaging were tested by measuring procollagen type I, transforming growth factor (TGF)-β1, and matrix metalloproteinase (MMP)-1 after UVB irradiation. The RJ contained about 0.211% 10-HDA. The UVB-irradiated human skin fibroblasts treated with RJ and 10-HDA had increased procollagen type I and TGF-β1 productions, but the level of MMP-1 was not changed. Thus RJ may potentially protect the skin from UVB-induced photoaging by enhancing collagen production.

  14. Geographical influences on content of 10-hydroxy-trans-2-decenoic acid in royal jelly in China.

    Science.gov (United States)

    Wei, Wen-Ting; Hu, Yuan-Qiang; Zheng, Huo-Qing; Cao, Lian-Fei; Hu, Fu-Liang; Hepburn, H Randall

    2013-10-01

    The content of 10-hydroxy-trans-2-decenoic acid (10-HDA), a marker compound in royal jelly (RJ), is the most important criterion in grading RJ for commercial trade and varies with its origin. To identify the effect of geographical origin on 10-HDA content in RJ, 138 samples were collected from 19 provinces of China (divided into three groups) produced by either Apis mellifera ligustica Spinola, 1806 or a hybrid of A. m. ligustica and Apis mellifera carnica Pollman, 1879 and analyzed for moisture, sugar, crude protein, ash, acid, and 10-HDA concentration. The results show that RJ from western China has a significantly higher 10-HDA level (2.01 +/- 0.05%) than those from northeastern (1.87 +/- 0.05%) and eastern (1.75 +/- 0.03%) China. RJ secreted by hybrid bees contained more 10-HDA (1.89 +/- 0.03%) than that secreted by A. m. ligustica (1.78 +/- 0.03%). The 10-HDA content of RJ produced during flowering of rape (Brassica campestris L.), lime (Tilia amurensis Ruprecht), and vitex (Vitex negundo L. variety heterophylla (Franch.) Rehder) was 1.92, 1.80, and 1.68%, respectively. The results would be helpful during the process of price determination of RJ by providing some basis of geographical, bee strain, and botanical information for commercial trade.

  15. The Royal Academy of moral and political sciences and the emergence of social sciences in Spain (1857-1923

    Directory of Open Access Journals (Sweden)

    Elodie Richard

    2015-05-01

    Full Text Available This article deals with the emergence of social sciences in Spain at the end of the nineteenth century. It focuses on the Royal Academy of moral and political sciences, whose creation in 1857, on the French model, was part of the reorganisation of public education, but also an ideological reaction of the conservative party (partido moderado, which returned to power after the 1854-1956 Revolution. The Academy was officially in charge of propagating the political doctrines of the regime (namely “doctrinaire” liberalism and of countering socialism at the scientific level. This paper shows the methodological relevance of studying such a multidisciplinary institution in order to grasp simultaneously the pluralistic scientific matrix of the social sciences as well as the political issues that surround them. It analyses the content and the evolution of moral and political sciences between 1857 and 1923 and highlights the multiple factors that played an active role in the emergence of the social sciences: the legacy of former scholarly disciplines, the impact of the propagation of naturalistic theories during the liberal revolution of 1868, and the critique of liberalism and liberal sciences following the social and political crisis from the 1880s onwards.

  16. Quantification of Selected Trace and Mineral Elements in Royal Jelly from Bulgaria by Icp-Oes and Etaas

    Directory of Open Access Journals (Sweden)

    Balkanska Ralitsa

    2017-12-01

    Full Text Available The objective of the present study was to investigate selected trace and mineral elements in Royal Jelly (RJ from Bulgaria. A total of 30 RJ samples were included in the study. The analytical procedure consisted of the microwave digestion of the RJ samples with nitric acid followed by instrumental measurement. Concentrations of Al, Ba, Ca, Cr, Cu, Fe, K, Mg, Mn, Na, P, Sr and Zn were determined using inductively coupled plasma optical emission spectroscopy (ICP-OES, while As, Cd, Co, Ni and Pb were determined by electrothermal atomic absorption spectrometry (ETAAS. Our results showed that elements K, Mg, Ca represented 96% from the total mineral content of the RJ samples from Bulgaria, while the most abundant trace element was Na, followed by Zn. The elements Ba, Cr, Cu, Fe, Mn and Sr were found in trace concentration levels and elements As, Pb, Cd, Co and Ni in microconcentration levels. Selected mineral and trace elements were found in relatively constant concentration levels in all of the analyzed RJ samples. It was concluded that chemical element content did not depend on geographical origin and was under homeostatic adjustment in RJs.

  17. Essential diagnostics - the role of the Department of Biomedical Research of the Royal Tropical Institute in the 21st century

    Directory of Open Access Journals (Sweden)

    Paul R Klatser

    2000-01-01

    Full Text Available In the light of emerging and overlooked infectious diseases and widespread drug resistance, diagnostics have become increasingly important in supporting surveillance, disease control and outbreak management programs. In many low-income countries the diagnostic service has been a neglected part of health care, often lacking quantity and quality or even non-existing at all. High-income countries have exploited few of their advanced technical abilities for the much-needed development of low-cost, rapid diagnostic tests to improve the accuracy of diagnosis and accelerate the start of appropriate treatment. As is now also recognized by World Healt Organization, investment in the development of affordable diagnostic tools is urgently needed to further our ability to control a variety of diseases that form a major threat to humanity. The Royal Tropical Institute's Department of Biomedical Research aims to contribute to the health of people living in the tropics. To this end, its multidisciplinary group of experts focuses on the diagnosis of diseases that are major health problems in low-income countries. In partnership we develop, improve and evaluate simple and cheap diagnostic tests, and perform epidemiological studies. Moreover, we advice and support others - especially those in developing countries - in their efforts to diagnose infectious diseases.

  18. The modulating effect of royal jelly consumption against radiation-induced apoptosis in human peripheral blood leukocytes

    Directory of Open Access Journals (Sweden)

    Navid Rafat

    2016-01-01

    Full Text Available The present work was designed to assess the radioprotective effect of royal jelly (RJ against radiation-induced apoptosis in human peripheral blood leukocytes. In this study, peripheral blood samples were obtained on days 0, 4, 7, and 14 of the study from six healthy male volunteers taking a 1000 mg RJ capsule orally per day for 14 consecutive days. On each sampling day, all collected whole blood samples were divided into control and irradiated groups which were then exposed to the selected dose of 4 Gy X-ray. Percentage of apoptotic cells (Ap % was evaluated for all samples immediately after irradiation (Ap0 and also after a 24 h postirradiation incubation at 37°C in 5% CO2 (Ap24 by the use of neutral comet assay. Concerning Ap0, collected data demonstrated that the percentage of apoptotic cells in both control and irradiated groups did not significantly change during the study period. However, with respect to Ap24, the percentage of apoptotic cells in irradiated groups gradually reduced during the experiment, according to which a significant decrease was found after 14 days RJ consumption (P = 0.002. In conclusion, the present study revealed the protective role of 14 days RJ consumption against radiation-induced apoptosis in human peripheral blood leukocytes.

  19. Going the distance: early results of a distributed medical education initiative for Royal College residencies in Canada.

    Science.gov (United States)

    Myhre, Douglas L; Hohman, Stacey

    2012-01-01

    There is a shortage of specialty physicians practising in rural Canada: only 2.4% of Canadian specialist physicians practise rurally. Numerous strategies have been proposed and attempted that aim to increase the number of rural physicians. These include undergraduate and postgraduate distributed medical education opportunities. The Distributed Royal College Initiative at the University of Calgary is increasing the exposure of specialty residents to rural medicine through regional rotations and electives. An assessment of the initial impacts of this programme was made. Specialty residents were sent a voluntary survey following their regional rotation in academic year 2010-2011. The survey measured each resident's satisfaction with the experience, interest in undertaking another rotation and the impact of the rotation on potential rural practice location. The survey asked for written comments on the rotation. Data were analysed using descriptive statistics. A total of 73% (29) of the 40 eligible residents completed the survey that was distributed upon completion of the rotation. In the survey, 45% of respondents indicated they would have been likely to practise in a regional community prior to the experience. This changed to 76% following the rotation. Analysis of the comments revealed strong positive characteristics of the experience across all disciplines. Specialty-based, rural distributed programmes were perceived by the residents as educationally valuable and may be crucial in helping shift attitudes towards rural practice. Specific successful characteristics of the rotations provide direction to increase their quality further. These findings need to be verified in a larger sample.

  20. Inpatient antibiotic consumption in a regional secondary hospital in New Zealand.

    Science.gov (United States)

    Hopkins, C J

    2014-02-01

    Reporting of antibiotic consumption in hospitals is a crucial component of antibiotic stewardship, but data from Australasian secondary hospitals are scarce. The hypothesis of this audit is that antibiotic consumption in secondary hospitals would be lower than in tertiary centres. The study aims to present the first published audit of antibiotic consumption from a secondary hospital in New Zealand compared with two tertiary centres. Hospital population-level data were retrospectively accessed to identify all systemic antibiotics dispensed to adult inpatients at Taranaki District Health Board during 2011. Consumption was calculated in defined daily doses per 100 inpatient-days and per 100 admissions, stratified by drug class. Comparison was against published data from two tertiary centres. Total consumption was lower, but that of high-risk antibiotic classes was higher than both tertiary centres. The relative consumption of lincosamides was 4.0 and 2.6 times higher than the two tertiary centres, with an associated 14% incidence of Clostridium difficile associated diarrhoea within 3 months. Our secondary hospital appears to consume the wrong types of antibiotic rather than too much. Data from all Australasian hospitals, stratified by clinical service area and hospital level, are required for clinically relevant benchmarking. © 2014 The Author; Internal Medicine Journal © 2014 Royal Australasian College of Physicians.

  1. Service Robots for Hospitals

    DEFF Research Database (Denmark)

    Özkil, Ali Gürcan

    services to maintain the quality of healthcare provided. This thesis and the Industrial PhD project aim to address logistics, which is the most resource demanding service in a hospital. The scale of the transportation tasks is huge and the material flow in a hospital is comparable to that of a factory. We......Hospitals are complex and dynamic organisms that are vital to the well-being of societies. Providing good quality healthcare is the ultimate goal of a hospital, and it is what most of us are only concerned with. A hospital, on the other hand, has to orchestrate a great deal of supplementary...... believe that these transportation tasks, to a great extent, can be and will be automated using mobile robots. This thesis consequently addresses the key technical issues of implementing service robots in hospitals. In simple terms, a robotic system for automating hospital logistics has to be reliable...

  2. Hospitality and Institutional Meals

    DEFF Research Database (Denmark)

    Justesen, Lise; Strøjer, Anna-Lise

    2017-01-01

    Abstract: There is a growing interest in articulating institutional meal serving practices as a hospitality activity involving host and guest interactions. This study aims to qualify institutional hospitality and meal activities by exploring private hospitality events. The study is based......-structured interview, students reflected on their hospitality experiences. The interviews were transcribed and analyzed using a thematic analysis method. The emerging themes on hospitality activities were identified. It was found that hospitality activities could be characterized as a process where the individual...... was transformed into a guest. Information on purpose of the event and other information given in the invitation were part of this process. Furthermore, hospitality activities could be characterized by blurred host-guest relations and by being able to embrace unexpected events as well. The activities were...

  3. Hospital turnaround strategies.

    Science.gov (United States)

    Langabeer, James

    2008-01-01

    Despite reports of higher profitability in recent years, hospitals are failing at a faster rate than ever before. Although many hospitals leave decisions regarding revenues and costs to chief financial officers and their staff, this is a recipe for disaster. From research conducted over the last 4 years on hospital bankruptcies and turnarounds, the author found that a common series of actions will help organizations evade collapse. The author explored these turnaround strategies through research and analysis of a variety of hospitals and health systems that had a high probability of immediate financial crisis or collapse. His continued observation and analysis of these hospitals in subsequent years showed that most hospitals never emerge from their bleak financial conditions. However, a few hospital administrations have successfully turned around their organizations.

  4. ELEMENTAL FORMS OF HOSPITALITY

    Directory of Open Access Journals (Sweden)

    Maximiliano Emanuel Korstanje

    2010-11-01

    Full Text Available Modern studies emphasized on the needs of researching the hospitality as relevant aspects of tourism and hospitality fields. Anyway, these approaches are inextricably intertwined to the industry of tourism and do not take seriously the anthropological and sociological roots of hospitality. In fact, the hotel seems to be a partial sphere of hospitality at all. Under this context, the present paper explores the issue of hospitality enrooted in the political and economic indo-European principle of free-transit which is associated to a much broader origin.  Starting from the premise etymologically hostel and hospital share similar origins, we follow the contributions of J Derrida to determine the elements that formed the hospitality up to date.

  5. Sir John Struthers (1823-1899), Professor of Anatomy in the University of Aberdeen (1863-1889), President of the Royal College of Surgeons of Edinburgh (1895-1897).

    Science.gov (United States)

    Kaufman, M H

    2015-11-01

    Between 1841 and 1845 John Struthers attended both the University of Edinburgh and some of the various Extra-mural Schools of Medicine associated with Surgeons' Hall. While a medical student he became a Member of the Hunterian Medical Society of Edinburgh and later was elected one of their Annual Presidents. He graduated with the MD Edin and obtained both the LRCS Edin and the FRCS Edin diplomas in 1845. Shortly afterwards he was invited to teach Anatomy in Dr Handyside's Extra-mural School in Edinburgh. The College of Surgeons certified him to teach Anatomy in October 1847. He had two brothers, and all three read Medicine in Edinburgh. His younger brother, Alexander, died of cholera in the Crimea in 1855 while his older brother James, who had been a bachelor all his life, practised as a Consultant Physician in Leith Hospital, Edinburgh, until his death.When associated with Dr Handyside's Extra-mural School in Edinburgh, John taught Anatomy there until he was elected to the Chair of Anatomy in Aberdeen in 1863. Much of his time was spent in Aberdeen teaching Anatomy and in upgrading the administrative facilities there. He resigned from this Chair in 1889 and subsequently was elected President of Leith Hospital from 1891 to 1897. This was in succession to his older brother, James, who had died in 1891. Later, he was elected President of the Royal College of Surgeons of Edinburgh from 1895 to 1897 and acted as its Vice-President from 1897 until his death in 1899. In 1898, Queen Victoria knighted him. His youngest son, John William Struthers, was the only one of his clinically qualified sons to survive him and subsequently was elected President of the Edinburgh College of Surgeons from 1941 to 1943. © The Author(s) 2014.

  6. Radioactive Substances Act 1993. Explanatory document and draft authorisation prepared by the Environment Agency to Assist public consultation on application by Devonport Royal Dockyard Limited to dispose of radioactive wastes from Devonport Royal Dockyard Plymouth Devon

    International Nuclear Information System (INIS)

    2000-01-01

    The Environment Agency (the Agency) is the independent public body responsible for regulating the use of radioactive substances and accumulation and disposal of radioactive wastes in order to ensure protection of people and the environment. Anyone who is proposing activities involving the use of radioactive substances or disposal of radioactive waste must apply for permission from the Agency. In 1993, the Government decided to locate all nuclear submarine refit work at Devonport. This will lead to increased amounts of radioactive waste arisings at Devonport and a decreased amount of waste arisings at Rosyth, where refit work was also previously carried out. In May 2000 Devonport Royal Dockyard Limited (DML) applied to the Agency for a variation to its authorisations under the Radioactive Substances Act 1993 to dispose of gaseous, liquid, and solid radioactive wastes from its site at Devonport in Plymouth. Once the application was received, the Agency made the information publicly available and held a well attended public meeting in Plymouth to highlight the issues. Since then the Agency has required DML to provide additional information in support of its application. Six rounds of questions were asked and responded to, and these responses have also been made publicly available. The application and responses from the company have been made publicly available. The Agency is now consulting widely on this information to assist its decision making. This Explanatory Document and the accompanying draft authorisation has been prepared by the Agency to assist the consultation process. They are intended to help members of the public and other consultees to understand the application and the Agency's considerations so far. The consultation is being carried out to enable the public and other consultees to draw the Agency's attention to any matters they would wish it to consider when reaching its decisions on this application. The Agency has not made any decisions on the DML

  7. Uso do 1-metilciclopropeno no controle da maturação de maçãs cv. 'Royal Gala' 1-Methylcyclopropene in the control of the ripening and in maintenance of quality of 'Royal Gala'apples

    Directory of Open Access Journals (Sweden)

    Adriana Regina Corrent

    2005-08-01

    Full Text Available Avaliou-se o efeito do 1-metilciclopropeno (1-MCP no controle da maturação de maçãs 'Royal Gala'. As frutas foram colhidas em dois estádios de maturação caracterizados como: estádio de maturação 1, com frutas apresentando firmeza de polpa de 82,14 N, acidez total titulável de 0,36 % de ácido málico, teor de sólidos solúveis totais de 14,10 ºBrix e produção de etileno de 2,00 nL.g-1.h-1, e estádio de maturação 2, com maçãs apresentando firmeza de polpa de 79,96 N, acidez total titulável de 0,33 % de ácido málico, teor de sólidos solúveis totais de 13,74 ºBrix e produção de etileno de 17,11 nL.g-1.h-1. Foram testadas quatro concentrações de 1-MCP: 0; 312; 625 e 1250 nL.L-1. A aplicação foi efetuada durante 48 horas, à temperatura de 20 ± 2 ºC, em câmaras com capacidade para 300 L. Após a aplicação, as frutas foram armazenadas a 20 ± 2 ºC, por 60 dias. A cada 10 dias, avaliaram-se a firmeza de polpa, a acidez total titulável, o teor de sólidos solúveis totais e a produção de etileno. O 1-MCP reduziu a produção de etileno nas maçãs e retardou a ocorrência do pico climatérico, independentemente do estádio de maturação e da concentração do produto. Em conseqüência, preservou maiores valores de firmeza de polpa e acidez total titulável.In the present work were evaluated the effects of 1-MCP on 'Royal Gala' apples ripening. The apples were harvested at two ripeness stages: Ripeness stage at harvest one apples were with 82, 4 N flesh firmness, 0,36 % malic acid and 14,10 ºBrix. Ethylene prodution of these apples was about 2,0 nL.g-1.h-1. Apples of ripeness stage 2 produced about 17,0 nL.g-1.h-1 ethylene and had flesh firmness values 79,96 N, 0,33 % malic acid and 13,74 ºBrix. The apples were treated with 1-methylcyclopropene (1-MCP using three concentrations and one control, 0, 325, 625 and 1250 nL.L-1 which were applied during 48 hours at temperature of 20 ± 2 ºC. After this time the

  8. Music therapy with hospitalized infants-the art and science of communicative musicality.

    Science.gov (United States)

    Malloch, Stephen; Shoemark, Helen; Črnčec, Rudi; Newnham, Carol; Paul, Campbell; Prior, Margot; Coward, Sean; Burnham, Denis

    2012-07-01

    Infants seek contingent, companionable interactions with others. Infants in a Neonatal Intensive Care Unit (NICU), while receiving care that optimizes their chances of survival, often do not have the kind of interactions that are optimal for their social development. Live music therapy (MT) with infants is an intervention that aims for contingent, social interaction between therapist and infant. This study, with a limited numbers of infants, examined the effectiveness of an MT intervention in the NICU at The Royal Children's Hospital Melbourne. Two groups of late pre-term and full-term infants were recruited to the study; one was given MT and the other was not. A healthy group of infants not given MT served as an additional control. The effect of MT was indexed using two measures reflecting infant social engagement: the Neurobehavioral Assessment of the Preterm Infant (NAPI) and the Alarm Distress Baby Scale (ADBB). Results suggest that the MT intervention used at The Royal Children's Hospital Melbourne supports infants' neurobehavioral development. In particular, hospitalized infants who received MT were better able to maintain self-regulation during social interaction with an adult, were less irritable and cried less, and were more positive in their response to adult handling, when compared with infants who did not receive the intervention. These are important prerequisites for social interaction and development. Further and larger scale research using MT with this population is indicated. Copyright © 2012 Michigan Association for Infant Mental Health.

  9. Hospital diversification strategy.

    Science.gov (United States)

    Eastaugh, Steven R

    2014-01-01

    To determine the impact of health system restructuring on the levels of hospital diversification and operating ratio this article analyzed 94 teaching hospitals and 94 community hospitals during the period 2008-2013. The 47 teaching hospitals are matched with 47 other teaching hospitals experiencing the same financial market position in 2008, but with different levels of preference for risk and diversification in their strategic plan. Covariates in the analysis included levels of hospital competition and the degree of local government planning (for example, highly regulated in New York, in contrast to Texas). Moreover, 47 nonteaching community hospitals are matched with 47 other community hospitals in 2008, having varying manager preferences for service-line diversification and risk. Diversification and operating ratio are modeled in a two-stage least squares (TSLS) framework as jointly dependent. Institutional diversification is found to yield better financial position, and the better operating profits provide the firm the wherewithal to diversify. Some services are in a growth phase, like bariatric weight-loss surgery and sleep disorder clinics. Hospital managers' preferences for risk/return potential were considered. An institution life cycle hypothesis is advanced to explain hospital behavior: boom and bust, diversification, and divestiture, occasionally leading to closure or merger.

  10. ANNUAL BALI INTERNATIONAL COMBINED CLINICAL MEETING

    Directory of Open Access Journals (Sweden)

    John Svigos

    2015-08-01

    Full Text Available Background: This valuable collaboration between Adelaide and Bali was first convened by Prof. I G. Surya, the late Prof. Made Kornia and Associate Prof. John Svigos in May 2011 at Sanglah General Hospital, Bali-Indonesia. This is a three day clinical meeting consisting of a daily Plenary Session for formal presentations running along with a Concurrent Session predominantly for “hands on” and interactive teaching. The meeting has a multidisciplinary focus which is in tune with contemporary Maternal Fetal Medicine practice and consists of obstetricians, midwives, neonatologists and obstetric anaesthetists from both cities sharing their respective experiences. From an initial modest meeting with 80 registrants this has now grown to over 300 registrants in 2015. A fourth day was trialed in 2014 in which a Field Day was incorporated into the program and enabled the overseas participants to gain some first hand experience in the workings of an orphanage (Anak Anak Bali Kids, a midwife obstetric unit (Bumi Sehat and a level two hospital (Sanjiwani Hospital, Gianyar. Further Field Days are anticipated at future meetings. The Visiting Faculty from Australia are predominantly from the Women’s and Children’s Hospital with input from The Lyell McEwin Hospital both in Adelaide, The Royal North Shore Hospital and the Royal Prince Alfred Hospital in Sydney and the King Edward Memorial Hospital in Perth. The broader strategic aspects of the collaboration have seen the rotation of three MFM Trainees from the Trigonum (Denpasar, Surabaya and Malang through Adelaide for two months in 2011 and 2012 as part of their MFM training. Unfortunately AusAID funding has not been forthcoming for further rotations to occur but in 2016 a multidisciplinary group from Sanglah General Hospital will be making a one week visit to the Women’s and Children’s Hospital as a forerunner to further visits. Meantime the collaborations with the Dr. Soetomo Hospital, Surabaya and

  11. Thematic village Zalesie Royal

    Directory of Open Access Journals (Sweden)

    Maria Dombrowicz

    2016-08-01

    Full Text Available Zalesie Królewskie is a village located in the district lay in the municipality of Swiekatowo. It is a town with well-preserved heritage Borowiakow Tucholskich. This heritage is rich and focused around the values of material culture, but also immaterial. People who live here have many features in common with neighboring Kociewiacy and Kashubian, but also have their own unique ethnographic, which is attractive for tourism.

  12. A royal visit

    CERN Multimedia

    Katarina Anthony

    2014-01-01

    On Wednesday, 21 May, CERN received His Majesty Philippe, King of the Belgians, for a full-day visit of the Laboratory.   From left to right: Tiziano Camporesi, CMS Spokesperson; François Englert, Nobel Prize in Physics 2013; Rolf Heuer, CERN Director-General; His Majesty Philippe, King of the Belgians; Philippe Courard, Belgium's State Secretary for Scientific Policy and Walter Van Doninck, CERN Council Vice-President. Director-General Rolf Heuer welcomed King Philippe to CERN at Point 5 (Cessy). This was to be no small visit, with His Majesty accompanied by a host of diplomats, prominent Belgian physicists - including François Englert - and even members of Belgium's press corps. After quick introductions, the morning began with a tour of the CMS underground experimental area and the LHC tunnel at Point 5, guided by the CMS Collaboration Spokesperson, Tiziano Camporesi, and the Director for Accelerators and Technology, Frédérick Bord...

  13. A royal visit

    CERN Multimedia

    2009-01-01

    On 19 February Albert II, King of the Belgians, visited CERN. He took a very active interest during his tour of the tunnel and the CMS cavern, in particular the pixel detector, which was made in Belgium. var flash_video_player=get_video_player_path(); insert_player_for_external('Video/Public/Movies/2009/CERN-MOVIE-2009-002/CERN-MOVIE-2009-002-0753-kbps-640x360-25-fps-audio-64-kbps-44-kHz-stereo', 'mms://mediastream.cern.ch/MediaArchive/Video/Public/Movies/2009/CERN-MOVIE-2009-002/CERN-MOVIE-2009-002-Multirate-200-to-753-kbps-640x360-25-fps.wmv', 'false', 533, 300, 'https://mediastream.cern.ch/MediaArchive/Video/Public/Movies/2009/CERN-MOVIE-2009-002/CERN-MOVIE-2009-002-posterframe-640x360-at-10-percent.jpg', '1164771', true, 'Video/Public/Movies/2009/CERN-MOVIE-2009-002/CERN-MOVIE-2009-002-0600-kbps-maxH-360-25-fps-audio-128-kbps-48-kHz-stereo.mp4'); Watch the video! Albert II, King of the Belgians receiving a souvenir from Sergio Bertolucci, Director for Research and...

  14. Hospital Dermatology, Introduction.

    Science.gov (United States)

    Fox, Lindy P

    2017-03-01

    Inpatient dermatology is emerging as a distinct dermatology subspecialty where dermatologists specialize in caring for patients hospitalized with skin disease. While the main focus of inpatient dermatology is the delivery of top-quality and timely dermatologic care to patients in the hospital setting, the practice of hospital-based dermatology has many additional components that are critical to its success. ©2017 Frontline Medical Communications.

  15. Hospital-acquired listeriosis.

    Science.gov (United States)

    Graham, J C; Lanser, S; Bignardi, G; Pedler, S; Hollyoak, V

    2002-06-01

    We report four cases of listeriosis that occurred over a two-month period in north east England. Due to the apparent nosocomial acquisition of infection and the clustering of cases in time and place, extended epidemiological investigation was performed and the outbreak was traced to a caterer who was providing sandwiches for hospital shops. We discuss the difficulties in preventing food-borne listeriosis in the hospital setting. Copyright 2002 The Hospital Infection Society.

  16. Hospital Management Software Development

    OpenAIRE

    sobogunGod, olawale

    2012-01-01

    The purpose of this thesis was to implement a hospital management software which is suitable for small private hospitals in Nigeria, especially for the ones that use a file based system for storing information rather than having it stored in a more efficient and safer environment like databases or excel programming software. The software developed within this thesis project was specifically designed for the Rainbow specialist hospital which is based in Lagos, the commercial neurological cente...

  17. Oral administration of royal jelly restores tear secretion capacity in rat blink-suppressed dry eye model by modulating lacrimal gland function.

    Directory of Open Access Journals (Sweden)

    Toshihiro Imada

    Full Text Available Tears are secreted from the lacrimal gland (LG, a dysfunction in which induces dry eye, resulting in ocular discomfort and visual impairment. Honey bee products are used as a nutritional source in daily life and medicine; however, little is known about their effects on dry eye. The aim of the present study was to investigate the effects of honey bee products on tear secretion capacity in dry eye. We selected raw honey, propolis, royal jelly (RJ, pollen, or larva from commercially available honey bee products. Tear secretion capacity was evaluated following the oral administration of each honey bee product in a rat blink-suppressed dry eye model. Changes in tear secretion, LG ATP content, and LG mitochondrial levels were measured. RJ restored the tear secretion capacity and decrease in LG ATP content and mitochondrial levels to the largest extent. Royal jelly can be used as a preventative intervention for dry eye by managing tear secretion capacity in the LG.

  18. Evolution of the Yellow/Major Royal Jelly Protein family and the emergence of social behavior in honey bees.

    Science.gov (United States)

    Drapeau, Mark David; Albert, Stefan; Kucharski, Robert; Prusko, Carsten; Maleszka, Ryszard

    2006-11-01

    The genomic architecture underlying the evolution of insect social behavior is largely a mystery. Eusociality, defined by overlapping generations, parental brood care, and reproductive division of labor, has most commonly evolved in the Hymenopteran insects, including the honey bee Apis mellifera. In this species, the Major Royal Jelly Protein (MRJP) family is required for all major aspects of eusocial behavior. Here, using data obtained from the A. mellifera genome sequencing project, we demonstrate that the MRJP family is encoded by nine genes arranged in an approximately 60-kb tandem array. Furthermore, the MRJP protein family appears to have evolved from a single progenitor gene that encodes a member of the ancient Yellow protein family. Five genes encoding Yellow-family proteins flank the genomic region containing the genes encoding MRJPs. We describe the molecular evolution of these protein families. We then characterize developmental-stage-specific, sex-specific, and caste-specific expression patterns of the mrjp and yellow genes in the honey bee. We review empirical evidence concerning the functions of Yellow proteins in fruit flies and social ants, in order to shed light on the roles of both Yellow and MRJP proteins in A. mellifera. In total, the available evidence suggests that Yellows and MRJPs are multifunctional proteins with diverse, context-dependent physiological and developmental roles. However, many members of the Yellow/MRJP family act as facilitators of reproductive maturation. Finally, it appears that MRJP protein subfamily evolution from the Yellow protein family may have coincided with the evolution of honey bee eusociality.

  19. Optical Coherence Tomography of Retinal Degeneration in Royal College of Surgeons Rats and Its Correlation with Morphology and Electroretinography.

    Directory of Open Access Journals (Sweden)

    Kobu Adachi

    Full Text Available To evaluate the correlation between optical coherence tomography (OCT and the histological, ultrastructural and electroretinography (ERG findings of retinal degeneration in Royal College of Surgeons (RCS-/- rats.Using OCT, we qualitatively and quantitatively observed the continual retinal degeneration in RCS-/- rats, from postnatal (PN day 17 until PN day 111. These findings were compared with the corresponding histological, electron microscopic, and ERG findings. We also compared them to OCT findings in wild type RCS+/+ rats, which were used as controls.After PN day 17, the hyperreflective band at the apical side of the photoreceptor layer became blurred. The inner segment (IS ellipsoid zone then became obscured, and the photoreceptor IS and outer segment (OS layers became diffusely hyperreflective after PN day 21. These changes correlated with histological and electron microscopic findings showing extracellular lamellar material that accumulated in the photoreceptor OS layer. After PN day 26, the outer nuclear layer became significantly thinner (P < 0.01 and hyperreflective compared with that in the controls; conversely, the photoreceptor IS and OS layers, as well as the inner retinal layers, became significantly thicker (P < 0.001 and P = 0.05, respectively. The apical hyperreflective band, as well as the IS ellipsoid zone, gradually disappeared between PN day 20 and PN day 30; concurrently, the ERG a- and b-wave amplitudes deteriorated. In contrast, the thicknesses of the combined retinal pigment epithelium and choroid did not differ significantly between RCS-/- and RCS+/+ rats.Our results suggest that OCT demonstrates histologically validated photoreceptor degeneration in RCS rats, and that OCT findings partly correlate with ERG findings. We propose that OCT is a less invasive and useful method for evaluating photoreceptor degeneration in animal models of retinitis pigmentosa.

  20. Reflecting photonics: reaching new audiences through new partnerships - IYL 2015 and the Royal Horticultural Society Flower Show

    Science.gov (United States)

    Posner, Matthew T.; John, Pearl V.; Standen, Deanna; Wheeler, Natalie V.; van Putten, Lieke D.; Soper, Nathan; Parsonage, Tina L.; Wong, Nicholas H. L.; Brambilla, Gilberto

    2016-09-01

    The `Reflecting Photonics' show garden was exhibited at the 2015 Royal Horticultural Society (RHS) Flower Show in Tatton Park, UK, to celebrate the International Year of Light and Light-based Technologies. Elks-Smith Garden Design alongside landscapers `Turf N' Earth' collaborated with researchers, marketing and outreach professionals from the University of Southampton to design, construct and exhibit a photonics-themed garden. The garden and supporting exhibition united science and art to reach new audiences - particularly family groups alongside other key influencers to the young - and showcased the world-leading research in optical fibers at the university in an accessible manner. Researchers and a publicity professional, funded by the EPSRC Centre for Innovative Manufacturing in Photonics, developed an integrated approach to the event's public engagement and marketing. The overarching aim was to influence a positive change in the attitude of the garden visitors towards physics and photonics, with additional focus on promoting careers for women in STEM. The show garden won an RHS Gold Medal award and the coveted `People's Choice Award' for the best large garden. The project subsequently won the South East England Physics Network Public Engagement Innovation Project Award. Approximately 80,000 visitors saw the garden, with a further three million television viewers on a popular British gardening show. There were also over 75,400 Tweet impressions on social media. This paper discusses the project aims, explores the design of the garden and its relationship with the research, describes the work of the public engagement team, and outlines the impact of the event.