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Sample records for rita stewart ann

  1. Professor Stewart's incredible numbers

    CERN Document Server

    Stewart, Ian

    2015-01-01

    Ian Stewart explores the astonishing properties of numbers from 1 to10 to zero and infinity, including one figure that, if you wrote it out, would span the universe. He looks at every kind of number you can think of - real, imaginary, rational, irrational, positive and negative - along with several you might have thought you couldn't think of. He explains the insights of the ancient mathematicians, shows how numbers have evolved through the ages, and reveals the way numerical theory enables everyday life. Under Professor Stewart's guidance you will discover the mathematics of codes,

  2. Til lykke eller Rita

    DEFF Research Database (Denmark)

    Agger, Gunhild

    2012-01-01

    Med Rita og Lykke har den satiriske sædekomedie fået en renæssance. Sædekomedien lever af at udstille normbrud og satirisere over menneskenes omgangsformer og kommunikation eller mangel på samme. Det er netop det, der sker i Rita og Lykke, hvor det outrerede eksponeres for at latterliggøres....

  3. Rita Bottoms: Polyartist Librarian

    OpenAIRE

    Bottoms, Rita; Reti, Irene; Regional History Project, UCSC Library

    2005-01-01

    Project Director Irene Reti conducted fourteen hours of interviews with Rita Bottoms, Head of Special Collections at the University Library, UC Santa Cruz, shortly before her retirement in March 2003. This oral history provides a vivid and intimate look at thirty-seven years behind the scenes in the library's Special Collections. For thirty-seven years Bottoms dedicated herself to collecting work by some of the most eminent writers and photographers of the twentieth century, includin...

  4. Ang Rita 1

    OpenAIRE

    Loomis, Molly

    2012-01-01

    .wav and .mp3 versions of audio file Ang Rita describes in Sherpa difference aspects of his life as a yak herder and yak herding culture. Tape includes native names for yak, birth and death ceremonies; castration practices; differences between Sherpa and Tibetan customs regarding yaks; herding yaks as a child; herding calls; interactions with wolves; grazing practices; concerns about decline of yak herding and the environmental consequences; the future of yak herding; famous yak herders; t...

  5. Interview: Rita Colwell

    OpenAIRE

    Alucozai, Milad

    2012-01-01

    Dr. Rita Colwell is a renowned microbiologist and infectious disease expert as well as a Purdue Alumna. She served as the 11th director of the National Science Foundation (NSF) from 1998 to 2004. Currently, she serves as the President and CEO of CosmosID and is a Distinguished Professor at both the University of Maryland and Johns Hopkins University School of Public Health.

  6. Anne Fine

    Directory of Open Access Journals (Sweden)

    Philip Gaydon

    2015-04-01

    Full Text Available An interview with Anne Fine with an introduction and aside on the role of children’s literature in our lives and development, and our adult perceptions of the suitability of childhood reading material. Since graduating from Warwick in 1968 with a BA in Politics and History, Anne Fine has written over fifty books for children and eight for adults, won the Carnegie Medal twice (for Goggle-Eyes in 1989 and Flour Babies in 1992, been a highly commended runner-up three times (for Bill’s New Frock in 1989, The Tulip Touch in 1996, and Up on Cloud Nine in 2002, been shortlisted for the Hans Christian Andersen Award (the highest recognition available to a writer or illustrator of children’s books, 1998, undertaken the positon of Children’s Laureate (2001-2003, and been awarded an OBE for her services to literature (2003. Warwick presented Fine with an Honorary Doctorate in 2005. Philip Gaydon’s interview with Anne Fine was recorded as part of the ‘Voices of the University’ oral history project, co-ordinated by Warwick’s Institute of Advanced Study.

  7. 48. Le pavillon Liliane de Stewart

    OpenAIRE

    Cameron, Christina; Déom, Claudine; Valois, Nicole

    2018-01-01

    Le pavillon Liliane de Stewart Le pavillon Liliane de Stewart est situé à l’arrière du pavillon Marguerite-d’Youville, qui lui est mitoyen. Il en constitue en quelque sorte un agrandissement, mais il s’en différencie par son plus petit volume (trois étages). Les deux pavillons partagent quelques caractéristiques architecturales, dont le plan angulaire et le revêtement de brique chamois. Le pavillon Liliane de Stewart se distingue cependant par sa fenestration, surtout celle de la façade avant...

  8. Hurricane Rita Poster (September 22, 2005)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Hurricane Rita poster. Multi-spectral image from NOAA-16 shows Hurricane Rita as a category-4 hurricane in the Gulf of Mexico on September 22, 2005. Poster size is...

  9. Proteomic profiling of white muscle from freshwater catfish Rita rita.

    Science.gov (United States)

    Mohanty, Bimal Prasanna; Mitra, Tandrima; Banerjee, Sudeshna; Bhattacharjee, Soma; Mahanty, Arabinda; Ganguly, Satabdi; Purohit, Gopal Krishna; Karunakaran, Dhanasekar; Mohanty, Sasmita

    2015-06-01

    Muscle tissues contribute 34-48 % of the total body mass in fish. Proteomic analysis enables better understanding of the skeletal muscle physiology and metabolism. A proteome map reflects the general fingerprinting of the fish species and has the potential to identify novel proteins which could serve as biomarkers for many aspects of aquaculture including fish physiology and growth, flesh quality, food safety and aquatic environmental monitoring. The freshwater catfish Rita rita of the family Bagridae inhabiting the tropical rivers and estuaries is an important food fish with high nutritive value and is also considered a species of choice in riverine pollution monitoring. Omics information that could enhance utility of this species in molecular research is meager. Therefore, in the present study, proteomic analysis of Rita rita muscle has been carried out and functional genomics data have been generated. A reference muscle proteome has been developed, and 23 protein spots, representing 18 proteins, have been identified by MALDI-TOF/TOF-MS and LC-MS/MS. Besides, transcript information on a battery of heat shock proteins (Hsps) has been generated. The functional genomics information generated could act as the baseline data for further molecular research on this species.

  10. Professor Stewart's casebook of mathematical mysteries

    CERN Document Server

    Stewart, Ian

    2014-01-01

    Like its wildly popular predecessors Cabinet of Mathematical Curiosities and Hoard of Mathematical Treasures, Professor Stewart's brand-new book is a miscellany of over 150 mathematical curios and conundrums, packed with trademark humour and numerous illustrations. In addition to the fascinating formulae and thrilling theorems familiar to Professor Stewart's fans, the Casebook follows the adventures of the not-so-great detective Hemlock Soames and his sidekick Dr John Watsup (immortalised in the phrase 'Watsup, Doc?'). By a remarkable coincidence they live at 222B Baker Street, just a

  11. Chk2 mediates RITA-induced apoptosis.

    Science.gov (United States)

    de Lange, J; Verlaan-de Vries, M; Teunisse, A F A S; Jochemsen, A G

    2012-06-01

    Reactivation of the p53 tumor-suppressor protein by small molecules like Nutlin-3 and RITA (reactivation of p53 and induction of tumor cell apoptosis) is a promising strategy for cancer therapy. The molecular mechanisms involved in the responses to RITA remain enigmatic. Several groups reported the induction of a p53-dependent DNA damage response. Furthermore, the existence of a p53-dependent S-phase checkpoint has been suggested, involving the checkpoint kinase Chk1. We have recently shown synergistic induction of apoptosis by RITA in combination with Nutlin-3, and we observed concomitant Chk2 phosphorylation. Therefore, we investigated whether Chk2 contributes to the cellular responses to RITA. Strikingly, the induction of apoptosis seemed entirely Chk2 dependent. Transcriptional activity of p53 in response to RITA required the presence of Chk2. A partial rescue of apoptosis observed in Noxa knockdown cells emphasized the relevance of p53 transcriptional activity for RITA-induced apoptosis. In addition, we observed an early p53- and Chk2-dependent block of DNA replication upon RITA treatment. Replicating cells seemed more prone to entering RITA-induced apoptosis. Furthermore, the RITA-induced DNA damage response, which was not a secondary effect of apoptosis induction, was strongly attenuated in cells lacking p53 or Chk2. In conclusion, we identified Chk2 as an essential mediator of the cellular responses to RITA.

  12. The Trieste Lecture of John Stewart Bell

    International Nuclear Information System (INIS)

    Bassi, Angelo; Ghirardi, GianCarlo

    2007-01-01

    Delivered at Trieste on the occasion of the 25th Anniversary of the International Centre for Theoretical Physics, 2 November 1989. The video of this lecture is available here. Please see the PDF for the transcript of the lecture. General remarks by Angelo Bassi and GianCarlo Ghirardi During the autumn of 1989 the International Centre for Theoretical Physics, Trieste, celebrated the 25th anniversary of its creation. Among the many prestigious speakers, who delivered extremely interesting lectures on that occasion, was the late John Stewart Bell. All lectures have been recorded on tape. We succeeded in getting a copy of John's lecture. In the lecture, many of the arguments that John had lucidly stressed in his writings appear once more, but there are also extremely interesting new remarks which, to our knowledge, have not been presented elsewhere. In particular he decided, as pointed out by the very choice of the title of his lecture, to call attention to the fact that the theory presents two types of difficulties, which Dirac classified as first and second class. The former are those connected with the so-called macro-objectification problem, the latter with the divergences characterizing relativistic quantum field theories. Bell describes the precise position of Dirac on these problems and he stresses appropriately how, contrary to Dirac's hopes, the steps which have led to a partial overcoming of the second class difficulties have not helped in any way whatsoever to overcome those of the first class. He then proceeds to analyse the origin and development of the Dynamical Reduction Program and draws attention to the problems that still affect it, in particular that of a consistent relativistic generalization. When the two meetings Are there quantum jumps? and On the present status of Quantum Mechanics were organized in Trieste and Losinj (Croatia), on 5-10 September 2005, it occurred to us that this lecture, which has never been published, might represent an

  13. The Trieste Lecture of John Stewart Bell

    Energy Technology Data Exchange (ETDEWEB)

    Bassi, Angelo; Ghirardi, GianCarlo

    2007-03-23

    Delivered at Trieste on the occasion of the 25th Anniversary of the International Centre for Theoretical Physics, 2 November 1989. The video of this lecture is available here. Please see the PDF for the transcript of the lecture. General remarks by Angelo Bassi and GianCarlo Ghirardi During the autumn of 1989 the International Centre for Theoretical Physics, Trieste, celebrated the 25th anniversary of its creation. Among the many prestigious speakers, who delivered extremely interesting lectures on that occasion, was the late John Stewart Bell. All lectures have been recorded on tape. We succeeded in getting a copy of John's lecture. In the lecture, many of the arguments that John had lucidly stressed in his writings appear once more, but there are also extremely interesting new remarks which, to our knowledge, have not been presented elsewhere. In particular he decided, as pointed out by the very choice of the title of his lecture, to call attention to the fact that the theory presents two types of difficulties, which Dirac classified as first and second class. The former are those connected with the so-called macro-objectification problem, the latter with the divergences characterizing relativistic quantum field theories. Bell describes the precise position of Dirac on these problems and he stresses appropriately how, contrary to Dirac's hopes, the steps which have led to a partial overcoming of the second class difficulties have not helped in any way whatsoever to overcome those of the first class. He then proceeds to analyse the origin and development of the Dynamical Reduction Program and draws attention to the problems that still affect it, in particular that of a consistent relativistic generalization. When the two meetings Are there quantum jumps? and On the present status of Quantum Mechanics were organized in Trieste and Losinj (Croatia), on 5-10 September 2005, it occurred to us that this lecture, which has never been published, might represent

  14. Social Justice Leadership in Action: The Case of Tony Stewart

    Science.gov (United States)

    Canfield-Davis, Kathy; Gardiner, Mary E.; Joki, Russell A.

    2009-01-01

    Reflecting on the 140th anniversary of the Fourteenth Amendment (ratified July, 1868), this qualitative case study described a response by educator-activist Tony Stewart to the Aryan Nations, a neo-Nazi hate group that attempted to intimidate Stewart's community, Coeur d' Alene, Idaho, between 1972-2000. Stewart galvanized community response using…

  15. The Stylasterine coral Allopora stellulata (Stewart)

    NARCIS (Netherlands)

    Boschma, H.

    1960-01-01

    The description of Stylaster stellulatus Stewart was based on a specimen obtained at Tahiti, the coral was stated to be extremely rare, and only found at one small island in the neighbourhood. The description contains all the peculiarities for a specific definition of the coral, the salient points

  16. Leading Character?s Antisocial Personality Disorder In James B Stewart?s Blind Eye

    OpenAIRE

    Lestari, Ayu

    2016-01-01

    110705043 The title of this thesis isLeading Character?s Antisocial Personality Disorder in James B Stewart?s Blind Eyethat is research about antisocial personality of leading character in the novel, namely Dr. Michael Swango. The purpose of this thesis is to find out characteristic of Swango that show he has antisocial personality disorder and to know the causes of his disorder. The writer refers to theory antisocial personality disorder that take in a research of APA (American Psychiatri...

  17. Stewart-Treves syndrome: case report

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Wesley Pereira [Hospital A.C. Camargo, Sao Paulo, SP (Brazil). Mastology Dept.], e-mail: wesley.andrade@hotmail.com; Aguiar Junior, Samuel; Lopes, Ademar [Hospital A.C. Camargo, Sao Paulo, SP (Brazil). Pelvic Surgery Dept.; Batista, Ranyell Matheus Spencer S.; Ribeiro, Marcio Ventura [Hospital A.C. Camargo, Sao Paulo, SP (Brazil)

    2008-07-01

    In 1948 Stewart and Treves described a syndrome related to the association between lymphangiosarcoma and chronic lymphedema due to radical mastectomy and radiotherapy. Currently, literature data reveals around 400 published cases. However, this pathology is becoming each time rarer due to the growing indication of conservative breast surgery and sentinel lymphonode research, thus reducing the need of axillary lymph node dissection with subsequent lymphedema. Described will be the case of a woman that developed angiosarcoma in shoulder 17 years after mastectomy with adjuvant radiotherapy.Stewart-Treves syndrome is related to the rise of angiosarcoma in patients with chronic lymphedema. It is currently treated as a rare disease. We describe the case of a woman who developed angiosarcoma in shoulder 17 years after mastectomy with adjuvant radiotherapy. (author)

  18. Stewart-Treves syndrome: case report

    International Nuclear Information System (INIS)

    Andrade, Wesley Pereira

    2008-01-01

    In 1948 Stewart and Treves described a syndrome related to the association between lymphangiosarcoma and chronic lymphedema due to radical mastectomy and radiotherapy. Currently, literature data reveals around 400 published cases. However, this pathology is becoming each time rarer due to the growing indication of conservative breast surgery and sentinel lymphonode research, thus reducing the need of axillary lymph node dissection with subsequent lymphedema. Described will be the case of a woman that developed angiosarcoma in shoulder 17 years after mastectomy with adjuvant radiotherapy.Stewart-Treves syndrome is related to the rise of angiosarcoma in patients with chronic lymphedema. It is currently treated as a rare disease. We describe the case of a woman who developed angiosarcoma in shoulder 17 years after mastectomy with adjuvant radiotherapy. (author)

  19. 27 CFR 9.162 - Sta. Rita Hills.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Sta. Rita Hills. 9.162.... Rita Hills. (a) Name. The name of the viticultural area described in this section is “Sta. Rita Hills”. For purposes of part 4 of this chapter, “Sta. Rita Hills” is a term of viticultural significance. (b...

  20. RITA-type triple axis spectrometers

    International Nuclear Information System (INIS)

    Roennow, H.M.

    2001-01-01

    The RITA spectrometer at Risoe National Laboratory was the first to incorporate a complete re-thinking of the neutron-path from source, through detector to analysis. Since then, other RITA-type spectrometers such as SPINS at NIST, RITA-II at PSI have been built, and several new spectrometers around the world are adapting the same philosophy. The main novelty of RITA was the introduction of a single back-end tank featuring both an analyser block with multiple individually turnable analyser blades and a 2D position sensitive detector. Several new triple-axis spectrometers are presently being built at existing and future sources, and almost all of them have learnt from the experience with RITA. (R.P.)

  1. Ann tuleb Rakverest Võrru

    Index Scriptorium Estoniae

    2009-01-01

    Võru kultuurimajas Kannel etendub 17. aprillil Rakvere teatri noortelavastus "Kuidas elad? ...Ann?!" Aidi Valliku jutustuse põhjal. Lavastaja Sven Heiberg. Mängivad ka Viljandi Kultuuriakadeemia teatritudengid

  2. Complete mitochondrial genome of the Freshwater Catfish Rita rita (Siluriformes, Bagridae).

    Science.gov (United States)

    Lashari, Punhal; Laghari, Muhammad Younis; Xu, Peng; Zhao, Zixia; Jiang, Li; Narejo, Naeem Tariq; Deng, Yulin; Sun, Xiaowen; Zhang, Yan

    2015-01-01

    The complete mitochondrial genome of Catfish, Rita rita, was isolated by LA PCR (TakaRa LAtaq, Dalian, China); and sequenced by Sanger's method to obtain the complete mitochondrial genome, which is listed Critically Endangered and Red Listed species. The complete mitogenome was 16,449 bp in length and contains 13 typical vertebrate protein-coding genes, 2 rRNA and 22 tRNA genes. The whole genome base composition was estimated to be 33.40% A, 27.43% C, 14.26% G and 24.89% T. The complete mitochondrial genome of catfish, Rita rita provides the basis for genetic breeding and conservation studies.

  3. iAnn

    DEFF Research Database (Denmark)

    Jimenez, Rafael C; Albar, Juan P; Bhak, Jong

    2013-01-01

    We present iAnn, an open source community-driven platform for dissemination of life science events, such as courses, conferences and workshops. iAnn allows automatic visualisation and integration of customised event reports. A central repository lies at the core of the platform: curators add...... submitted events, and these are subsequently accessed via web services. Thus, once an iAnn widget is incorporated into a website, it permanently shows timely relevant information as if it were native to the remote site. At the same time, announcements submitted to the repository are automatically...

  4. The Stewart approach--one clinician's perspective.

    Science.gov (United States)

    Morgan, T John

    2009-05-01

    Peter Stewart added controversy to an already troubled subject when he entered the clinical acid-base arena. His approach puts water dissociation at the centre of the acid-base status of body fluids. It is based on six simultaneous equations, incorporating the Laws of Mass Action, Mass Conservation, and Electrical Neutrality. Together with Gibbs-Donnan equilibria, these equations explain the diagnostically important PaCO(2)/pH relationship, and improve understanding of the physiologic basis of traditional acid-base approaches. Spin-offs have included new scanning tools for unmeasured ions, in particular the 'strong ion gap' and 'net unmeasured ions'. The most controversial feature is the designation of pH and bicarbonate concentrations as dependent variables, answerable exclusively to three independent variables. These are the strong ion difference (SID), the total concentration of non-volatile weak acid (A(TOT)), and PCO(2). Aspects of this assertion conflict with traditional renal physiology, and with current models of membrane H(+)/base transporters, oxidative phosphorylation, and proton and bicarbonate ionophores. The debate in this area is ongoing. Meanwhile, Stewart-style diagnostic and decision support systems such as the 'Strong Ion Calculator' and the web-site www.acidbase.org are now appearing.

  5. Astronauts McNair and Stewart prepare for reentry

    Science.gov (United States)

    1984-01-01

    Astronauts Ronald E. McNair and Robert L. Stewart prepare for the re-entry phase of the shuttle Challenger near the end of the 41-B mission. The are stationed behind the crew commander and pilot. Stewart is already wearing his helmet. McNair is stowing some of his gear.

  6. Anne-Ly Reimaa : "Suhtlemisel on oluline avatus" / Anne-Ly Reimaa ; interv. Tiia Linnard

    Index Scriptorium Estoniae

    Reimaa, Anne-Ly

    2005-01-01

    Ilmunud ka: Severnoje Poberezhje : Subbota 3. september lk. 5. Intervjueeritav oma tööst Brüsselis, kus esindab Eesti linnade liitu ja Eesti maaomavalitsuste liitu. Arvamust avaldavad Anne Jundas ja Kaia Kaldvee. Lisa: CV

  7. Lens proteome map and alpha-crystallin profile of the catfish Rita rita.

    Science.gov (United States)

    Mohanty, Bimal Prasanna; Bhattacharjee, Soma; Das, Manas Kumar

    2011-02-01

    Crystallins are a diverse group of proteins that constitute nearly 90% of the total soluble proteins of the vertebrate eye lens and these tightly packed crystallins are responsible for transparency of the lens. These proteins have been studied in different model and non-model species for understanding the modifications they undergo with ageing that lead to cataract, a disease of protein aggregation. In the present investigation, we studied the lens crystallin profile of the tropical freshwater catfish Rita rita. Profiles of lens crystallins were analyzed and crystallin proteome maps of Rita rita were generated for the first time. alphaA-crystallins, member of the alpha-crystallin family, which are molecular chaperons and play crucial role in maintaining lens transparency were identified by 1- and 2-D immunoblot analysis with anti-alphaA-crystallin antibody. Two protein bands of 19-20 kDa were identified as alphaA-crystallins on 1-D immunoblots and these bands separated into 10 discrete spots on 2-D immunoblot. However, anti-alphaB-crystallin and antiphospho-alphaB-crystallin antibodies were not able to detect any immunoreactive bands on 1- and 2-D immunoblots, indicating alphaB-crystallin was either absent or present in extremely low concentration in Rita rita lens. Thus, Rita rita alpha-crystallins are more like that of the catfish Clarias batrachus and the mammal kangaroo in its alphaA- and alphaB-crystallin content (contain low amount from 5-9% of alphaB-crystallin) and unlike the dogfish, zebrafish, human, bovine and mouse alpha-crystallins (contain higher amount of alphaB-crystallin from 25% in mouse and bovine to 85% in dogfish). Results of the present study can be the baseline information for stimulating further investigation on Rita rita lens crystallins for comparative lens proteomics. Comparing and contrasting the alpha-crystallins of the dogfish and Rita rita may provide valuable information on the functional attributes of alphaA- and alphaB-isoforms, as

  8. Wood-Fired Boiler System Evaluation at Fort Stewart, GA

    National Research Council Canada - National Science Library

    Potts, Noel

    2002-01-01

    Part of the plan to modernize the central energy plant (CEP) at Fort Stewart, GA is focused on the installations wood-fired boiler, which provides steam for heating, cooling, and domestic hot water. The U.S...

  9. Looking at the future with Rita.

    Science.gov (United States)

    Bentivoglio, M

    2013-11-12

    This paper on Rita Levi-Montalcini (1909-2012), who received in 1986 the Nobel Prize in Physiology or Medicine for the discovery of nerve growth factor, focuses on aspects of her advocacy and her commitment to education in which she has been especially active in the last part of her long life. With passionate confidence on the capabilities of the aging brain (together with severe admonition against the pursuit of immortality), she encouraged contributions of senior citizens to the society. Always projected into the future, with enduring faith in the potential of young individuals, in education as a key to development, in the capabilities of women, in the importance of gender equality, Rita established in 2001 the Rita Levi-Montalcini Foundation for the education of African women. Her legacy on engagement for a better 'global village' should not be forgotten by the neuroscience community.

  10. Realizing the full potential of a RITA spectrometer

    DEFF Research Database (Denmark)

    Lefmann, K.; Niedermayer, C.; Abrahamsen, A.B.

    2006-01-01

    The “re-invented triple-axis spectrometer (RITA) concept has existed for a decade. Recent developments at RITA-2 at PSI, have revealed more of the potential of this instrument class. We demonstrate the performance of the multi-blade imaging mode, which has been applied e.g. to studies of dispersion...... relations and emphasize the power of this mode in combination with the low background of RITA-2. In addition, we present other ways of utilizing the position sensitive detector in a RITA instrument. Simulations of a planned upgrade of the guide-monochromator system at RITA-2 have shown a potential...

  11. Ann Tenno salapaigad / Margit Tõnson

    Index Scriptorium Estoniae

    Tõnson, Margit, 1978-

    2011-01-01

    Fotograaf Ann Tenno aiandushuvist, pildistamisest maailma erinevates paikades. Uutest suundadest (fototöötlus, fractal art, soojuskaameraga pildistamine) tema loomingus. Katkendeid Ann Tenno 2010. aastal ilmunud proosaraamatust "Üle unepiiri"

  12. Antibacterial properties of the skin mucus of the freshwater fishes, Rita rita and Channa punctatus.

    Science.gov (United States)

    Kumari, U; Nigam, A K; Mitial, S; Mitial, A K

    2011-07-01

    The skin mucus of Rita rita and Channa punctatus was investigated to explore the possibilities of its antibacterial properties. Skin mucus was extracted in acidic solvents (0.1% trifluoroacetic acid and 3% acetic acid) and in triple distilled water (aqueous medium). The antibacterial activity of the mucus extracts was analyzed, using disc diffusion method, against five strains of bacteria--the Gram-positive Staphylococcus aureus and Micrococcus luteus; and the Gram negative Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi. In both Rita rita and Channa punctatus, the skin mucus extracted in acidic solvents as well as in aqueous medium show antibacterial activity against Staphylococcus aureus and Micrococcus luteus. Nevertheless, the activity is higher in acidic solvents than that in aqueous medium. The acidic mucus extracts of Rita rita, show antibacterial activity against Salmonella typhi as well. The results suggest that fish skin mucus have bactericidal properties and thus play important role in the protection of fish against the invasion of pathogens. Fish skin mucus could thus be regarded as a potential source of novel antibacterial components.

  13. Kõnelused Tartus / Anne Untera

    Index Scriptorium Estoniae

    Untera, Anne, 1951-

    2007-01-01

    8.-10. V Tartus toimunud eesti, läti ja saksa kunstiteadlaste ühisseminarist. Alexander Knorre rääkis Karl August Senffi, Ilona Audere Friedrich Ludwig von Maydelli, Mai Levin Karl Alexander von Winkleri, Kristiana Abele Johann Walter-Kurau (1869-1932), Anne Untera Konstantin ja Sally von Kügelgeni, Epp Preem Julie Hagen-Schwartzi, Friedrich Gross Eduard von Gebhardti ja Katharina Hadding Ida Kerkoviuse (1879-1970) loomingust

  14. Krimmi-Rita juubelituur Eestimaal / Enda Trubok

    Index Scriptorium Estoniae

    Trubok, Enda

    2010-01-01

    Kontši-Savva ehk Krasnodarka küla eesti seltsi esinaisel Rita Kadilkinal (neiupõlvenimi Kuusk), kelle esivanemad 1862. aastal Järvamaalt – Albu vallast – Krimmi paremaid maid otsima läksid, täitus septembris 70 eluaastat, mille puhul otsustaski ta Eestisse tulla

  15. Changes in pilot control behaviour across Stewart platform motion systems

    NARCIS (Netherlands)

    Nieuwenhuizen, F.M.

    2012-01-01

    Flight simulators provide an effective, efficient, and safe environment for practising flight-critical manoeuvres without requiring a real aircraft. Most simulators are equipped with a Stewart-type motion system, which consists of six linear actuators in a hexapod configuration. The argument for use

  16. "The Daily Show with Jon Stewart": Part 1

    Science.gov (United States)

    Trier, James

    2008-01-01

    Comedy Central's popular program "The Daily Show With Jon Stewart" is the best critical media literacy program on television, and it can be used in valuable ways in the classroom as part of a media literacy pedagogy. This Media Literacy column provides an overview of the show and its accompanying website and considers ways it might be used in the…

  17. A Response to Stewart, McElwee, and Ming

    Science.gov (United States)

    Martin, Garry L.; Yu, C. T.

    2010-01-01

    In a recent article published in "The Behavior Analyst," Stewart, McElwee, and Ming (2010) suggested that "scientific experts in scientific contexts" should use more "technically accurate and precise labeling" when describing the Assessment of Basic Learning Abilities (ABLA) in published articles. They concluded by stating, "We believe that…

  18. The Daily Show with Jon Stewart: Part 2

    Science.gov (United States)

    Trier, James

    2008-01-01

    "The Daily Show With Jon Stewart" is one of the best critical literacy programs on television, and in this Media Literacy column the author suggests ways that teachers can use video clips from the show in their classrooms. (For Part 1, see EJ784683.)

  19. Retention of Displaced Students after Hurricanes Katrina and Rita

    Science.gov (United States)

    Coco, Joshua Christian

    2017-01-01

    The purpose of the study was to investigate the strategies that university leaders implemented to improve retention of displaced students in the aftermaths of Hurricanes Katrina and Rita. The universities that participated in this study admitted displaced students after Hurricanes Katrina and Rita. This study utilized a qualitative…

  20. Simulations and experiments on RITA-2 at PSI

    DEFF Research Database (Denmark)

    Klausen, S.N.; Lefmann, K.; McMorrow, D.F.

    2002-01-01

    The cold-neutron triple-axis spectrometer RITA-2 designed and built at Riso National Laboratory was installed at the neutron source SINQ at Paul Scherrer Institute in April/May 2001. In connection with the installation of RITA-2, computer simulations were performed using the neutron ray...

  1. Realizing the full potential of a RITA spectrometer

    International Nuclear Information System (INIS)

    Lefmann, K.; Niedermayer, Ch.; Abrahamsen, A.B.; Bahl, C.R.H.; Christensen, N.B.; Jacobsen, H.S.; Larsen, T.L.; Haefliger, P.; Filges, U.; Ronnow, H.M.

    2006-01-01

    The 're-invented triple-axis spectrometer (RITA) concept has existed for a decade. Recent developments at RITA-2 at PSI, have revealed more of the potential of this instrument class. We demonstrate the performance of the multi-blade imaging mode, which has been applied e.g. to studies of dispersion relations and emphasize the power of this mode in combination with the low background of RITA-2. In addition, we present other ways of utilizing the position sensitive detector in a RITA instrument. Simulations of a planned upgrade of the guide-monochromator system at RITA-2 have shown a potential to increase the flux at the sample position by a factor 5

  2. Realizing the full potential of a RITA spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Lefmann, K. [Riso National Laboratory, Frederiksborgvej 399, DK-4000 Roskilde (Denmark)]. E-mail: kim.lefmann@risoe.dk; Niedermayer, Ch. [Laboratory for Neutron Scattering, ETH-Zuerich and Paul Scherrer Institut, CH-5232 Villilgen (Switzerland); Abrahamsen, A.B. [Riso National Laboratory, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Bahl, C.R.H. [Riso National Laboratory, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Christensen, N.B. [Riso National Laboratory, Frederiksborgvej 399, DK-4000 Roskilde (Denmark): Laboratory for Neutron Scattering, ETH-Zuerich and Paul Scherrer Institut, CH-5232 Villilgen (Switzerland); Jacobsen, H.S. [Niels Bohr Institute, University of Copenhagen, DK-2100 Copenhagen O (Denmark); Larsen, T.L. [Niels Bohr Institute, University of Copenhagen, DK-2100 Copenhagen O (Denmark); Haefliger, P. [Laboratory for Neutron Scattering, ETH-Zuerich and Paul Scherrer Institut, CH-5232 Villilgen (Switzerland); Filges, U. [Laboratory for Neutron Scattering, ETH-Zuerich and Paul Scherrer Institut, CH-5232 Villilgen (Switzerland); Ronnow, H.M. [Laboratory for Neutron Scattering, ETH-Zuerich and Paul Scherrer Institut, CH-5232 Villilgen (Switzerland)

    2006-11-15

    The 're-invented triple-axis spectrometer (RITA) concept has existed for a decade. Recent developments at RITA-2 at PSI, have revealed more of the potential of this instrument class. We demonstrate the performance of the multi-blade imaging mode, which has been applied e.g. to studies of dispersion relations and emphasize the power of this mode in combination with the low background of RITA-2. In addition, we present other ways of utilizing the position sensitive detector in a RITA instrument. Simulations of a planned upgrade of the guide-monochromator system at RITA-2 have shown a potential to increase the flux at the sample position by a factor 5.

  3. Morphological observation and length-weight relationship of critically endangered riverine catfish Rita rita (Hamilton).

    Science.gov (United States)

    Amin, M R; Mollah, M F A; Taslima, K; Muhammadullah

    2014-01-15

    The experiment was conducted to investigate the morphological status of the critically endangered riverine catfish Rita rita using morphometric and meristic traits. About 158 species of Rita were collected from the old Brahmaputra river in Mymensingh district and were studied in the laboratory of the Fisheries Biology and Genetics Department, Bangladesh Agricultural University. Measurement of length and weight of Rita were recorded by using measuring scale and electric balance respectively. Significant curvilinear relationship existed between total length and other morphometric characters and between head length and other characters of the head. Relationships between total length and various body measurements of the fish were highly significant (p < 0.01) except the relationship between total length and pelvic fin length of male fish (p < 0.05). In case of meristic characters-dorsal fin rays, pelvic fin rays, pectoral fin rays, anal fin rays, caudal fin rays, number of vertebrae and branchiostegal rays were found to be more or less similar except slight differences. The values of condition factors (k) in the total length body-weight relationships for female and male were found to be 0.41 and 0.38, respectively. The mean values of relative condition factors (kn) were 1.0 and 1.005 for female and male, respectively.

  4. RITA: The reinvented triple axis spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Mason, T.E. [Toronto Univ., ON (Canada). Dept. of Physics; Clausen, K.N.; Aeppli, G.; McMorrow, D.R.; Kjems, J.K. [Risoe National Lab., Roskilde (Denmark)

    1995-11-01

    Risoe National Laboratory was reported to be in the process of developing a new spectrometer design, RITA, based on the triple axis design. The spectrometer will attempt to incorporate more recent innovations such as multilayer supermirrors and microstrip proportional counters into a rethinking of the triple-axis spectrometer. By optimizing the beam optics, using supermirrors and extending the analyser to map regions of (Q, {omega}) space using an array of independently controllable pyrolytic graphite crystals focussed on an area detector, it was hoped that the efficiency of single-crystal inelastic experiments could be increased by as much as a factor of 20. 7 figs., 20 refs.

  5. RITA Mimics: Synthesis and Mechanistic Evaluation of Asymmetric Linked Trithiazoles.

    Science.gov (United States)

    Pietkiewicz, Adrian L; Zhang, Yuqi; Rahimi, Marwa N; Stramandinoli, Michael; Teusner, Matthew; McAlpine, Shelli R

    2017-04-13

    The established cytotoxic agent RITA contains a thiophene-furan-thiophene backbone and two terminal alcohol groups. Herein we investigate the effect of using thiazoles as the backbone in RITA-like molecules and modifying the terminal groups of these trithiazoles, thereby generating 41 unique structures. Incorporating side chains with varied steric bulk allowed us to investigate how size and a stereocenter impacted biological activity. Subjecting compounds to growth inhibition assays on HCT-116 cells showed that the most potent compounds 7d , 7e , and 7h had GI 50 values of 4.4, 4.4, and 3.4 μM, respectively, versus RITA (GI 50 of 800 nM). Analysis of these compounds in apoptosis assays proved that 7d , 7e , and 7h were as effective as RITA at inducing apoptosis. Evaluating the impact of 7h on proteins targeted by RITA (p53, c-Myc, and Mcl-1) indicated that it acts via a different mechanism of action to that of RITA. RITA suppressed Mcl-1 protein via p53, whereas compound 7h suppressed Mcl-1 expression via an alternative mechanism independent of p53.

  6. Children and Trauma: A Post-Katrina and Rita Response

    Science.gov (United States)

    Hebert, Barbara B.; Ballard, Mary B.

    2007-01-01

    Many children have struggled to cope with the traumatic experiences brought about by hurricanes Katrina and Rita. This article recounts how the authors intervened in the lives of children and families after the storms. (Contains 3 figures.)

  7. Rita Felski, The Limits of Critique

    Directory of Open Access Journals (Sweden)

    Corrado Confalonieri

    2017-05-01

    Full Text Available Professore di Letteratura inglese presso la University of Virginia – e dal 2016 Niels Bohr Professor alla University of Southern Denmark per un progetto quinquennale dedicato agli usi sociali della letteratura –, Rita Felski non è, all’interno del gruppo di studiosi che lavorano negli Stati Uniti, tra quelli più noti al pubblico italiano, e ciò non soltanto perché mancano traduzioni dei suoi libri, ma per il fatto che diversi tra questi sono rivolti a un contesto piuttosto specificamente americano. Non fa eccezione The Limits of Critique, il libro che qui si presenta e che dovrebbe costituire la seconda uscita di una trilogia avviata nel 2008 con Uses of Literature (Wiley-Blackwell e destinata a concludersi con un volume ora in fase di elaborazione dedicato al coinvolgimento estetico e alle ragioni per cui, come lettori o spettatori, siamo affascinati da un’opera d’arte.

  8. Adaptive control of a Stewart platform-based manipulator

    Science.gov (United States)

    Nguyen, Charles C.; Antrazi, Sami S.; Zhou, Zhen-Lei; Campbell, Charles E., Jr.

    1993-01-01

    A joint-space adaptive control scheme for controlling noncompliant motion of a Stewart platform-based manipulator (SPBM) was implemented in the Hardware Real-Time Emulator at Goddard Space Flight Center. The six-degrees of freedom SPBM uses two platforms and six linear actuators driven by dc motors. The adaptive control scheme is based on proportional-derivative controllers whose gains are adjusted by an adaptation law based on model reference adaptive control and Liapunov direct method. It is concluded that the adaptive control scheme provides superior tracking capability as compared to fixed-gain controllers.

  9. Ado Vabbe preemia Anne Parmastole

    Index Scriptorium Estoniae

    2003-01-01

    Tartu Kunstimajas Tartu kunsti aastalõpunäitus. Kujundaja Mari Nõmmela. Anne Parmastole A. Vabbe, Silja Salmistule E-Kunstisalongi, Lii Jürgensonile EDA, Jüri Marranile Wilde kohviku, Sami Makkonenile AS Vunder ja Tartu Õlletehase A. Le Coq ning Eda Lõhmusele AS Merko Tartu preemia

  10. Fort Stewart integrated resource assessment. Volume 3: Resource assessment

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, G.P.; Keller, J.M.; Stucky, D.J.; Wahlstrom, R.R.; Larson, L.L.

    1993-10-01

    The US Army Forces Command (FORSCOM) has tasked the US Department of Energy (DOE) Federal Energy Management Program (FEMP), supported by the Pacific Northwest Laboratory, to identify, evaluate, and assist in acquiring all cost-effective energy projects at Fort Stewart. This is part of a model program that PNL is designing to support energy-use decisions in the federal sector. This report provides the results of the fossil fuel and electric energy resource opportunity (ERO) assessments performed by PNL at the FORSCOM Fort Stewart facility located approximately 25 miles southwest of Savannah, Georgia. It is a companion report to Volume 1, Executive Summary, and Volume 2, Baseline Detail. The results of the analyses of EROs are presented in 11 common energy end-use categories (e.g., boilers and furnaces, service hot water, and building lighting). A narrative description of each ERO is provided, along with a table detailing information on the installed cost, energy and dollar savings; impacts on operations and maintenance (O&M); and, when applicable, a discussion of energy supply and demand, energy security, and environmental issues. A description of the evaluation methodologies and technical and cost assumptions is also provided for each ERO. Summary tables present the cost-effectiveness of energy end-use equipment before and after the implementation of each ERO. The tables also present the results of the life-cycle cost (LCC) analysis indicating the net present value (NPV) and savings to investment ratio (SIR) of each ERO.

  11. The Stewart Approach – One Clinician’s Perspective

    Science.gov (United States)

    Morgan, T John

    2009-01-01

    Peter Stewart added controversy to an already troubled subject when he entered the clinical acid-base arena. His approach puts water dissociation at the centre of the acid-base status of body fluids. It is based on six simultaneous equations, incorporating the Laws of Mass Action, Mass Conservation, and Electrical Neutrality. Together with Gibbs-Donnan equilibria, these equations explain the diagnostically important PaCO2/pH relationship, and improve understanding of the physiologic basis of traditional acid-base approaches. Spin-offs have included new scanning tools for unmeasured ions, in particular the ‘strong ion gap’ and ‘net unmeasured ions’. The most controversial feature is the designation of pH and bicarbonate concentrations as dependent variables, answerable exclusively to three independent variables. These are the strong ion difference (SID), the total concentration of non-volatile weak acid (ATOT), and PCO2. Aspects of this assertion conflict with traditional renal physiology, and with current models of membrane H+/base transporters, oxidative phosphorylation, and proton and bicarbonate ionophores. The debate in this area is ongoing. Meanwhile, Stewart-style diagnostic and decision support systems such as the ‘Strong Ion Calculator’ and the web-site www.acidbase.org are now appearing. PMID:19565024

  12. Implementation and validation of a model of the MPI Stewart platform

    NARCIS (Netherlands)

    Nieuwenhuizen, F.M.; Van Paasen, M.M.; Mulder, M.; Bülthoff, H.H.

    2010-01-01

    A simulated model of the MPI Stewart platform can be used to identify the influence of motion system characteristics on human control behaviour in active closed-loop control experiments on the SIMONA Research Simulator. In this paper, a previously identified model of the MPI Stewart platform was

  13. Underwater EVA training in the WETF with astronaut Robert L. Stewart

    Science.gov (United States)

    1983-01-01

    Underwater extravehicular activity (EVA) training in the weightless environment training facility (WETF) with astronaut Robert L. Stewart. Stewart is simulating a planned EVA using the mobile foot restraint device and a one-G version of the Canadian-built remote manipulator system.

  14. Improved Stewart platform state estimation using inertial and actuator position measurements

    NARCIS (Netherlands)

    MiletoviC, I.; Pool, D.M.; Stroosma, O.; van Paassen, M.M.; Chu, Q.

    2017-01-01

    Accurate and reliable estimation of the kinematic state of a six degrees-of-freedom Stewart platform is a problem of interest in various engineering disciplines. Particularly so in the area of flight simulation, where the Stewart platform is in widespread use for the generation of motion similar

  15. Rita Kirke: "Taimed on minu head õpetajad ja toetajad" / Rita Kirke

    Index Scriptorium Estoniae

    Kirke, Rita

    2006-01-01

    Elukutselisi aiakujundajaid tutvustavas sarjas vastab küsimustele läti aiakujundaja Rita Kirke. R. Kirkest, tema tähtsamad tööd. R. Kirke endast, oma õpetajatest, oma aiast ja töödest, Läti oludesse sobivast ja tüüpilisest Läti aiast, koostööst klientidega, lemmiktaimedest, taimede kättesaadavusest Lätis jpm. Ill.: R. Kirke portreefoto, 6 ill. tema töödest

  16. Anne-Ly Võlli: Iga inimene ja asutus vajab omamoodi lähenemist / Anne-Ly Võlli ; intervjueerinud Jaanika Kressa

    Index Scriptorium Estoniae

    Võlli, Anne-Ly, 1976-

    2009-01-01

    MTÜ Jõgevamaa Omavalitsuste Aktiviseerimiskeskus kinnitas avaliku konkursi tulemusel juhatuse liikmeks Anne-Ly Võlli, kelle ülesandeks on keskuse tegevuse juhtimine ja koostöö arendamine partneromavalitsuste ja teiste koostööpartnerite vahel

  17. Annely Peebo kutsus presidendi kontserdile / Maria Ulfsak

    Index Scriptorium Estoniae

    Ulfsak, Maria, 1981-

    2003-01-01

    Laulja Anneli Peebo kohtus president Arnold Rüütliga, et anda üle kutse Andrea Bocelli ja Annely Peebo ühiskontserdile. Vt. samas: Andrea Bocelli ja Annely Peebo kontsert Tallinna lauluväljakul 23. augustil; Andrea Bocelli

  18. [Meeting point Stewart. Buffer bases, base excess and strong ions].

    Science.gov (United States)

    Lang, W

    2007-04-01

    Development of a two-buffer model which simulates the acid-base properties of blood and allows comparison of the different acidbase concepts according to Stewart and to Siggaard-Andersen. The two-buffer model consisted of different aqueous solutions of bicarbonate/CO(2) (pCO(2), sCO(2), pK(1)), HEPES buffer (A(tot), pK(a)) and electrolytes. These were used to calculate the pH from the independent variables according to Stewart - strong ion difference (SID), pCO(2) and total concentration of the weak acids (A(tot)) - from which all other dependent variables (cHCO(3)(-), cA(-), BB, BE) were obtained and compared with the measured values. The normal pH (7.408) was calculated from the normal values for SID (48 mmol/l), pCO(2) (40 mmHg) and A(tot) (45.2 mmol/l) and agreed perfectly with the measured value (7.409+/-0.001). This was also valid for all calculated and measured pH values when the SID was varied: non-respiratory alkalosis ( upward arrow) or acidosis ( downward arrow), pCO(2):respiratory acidosis ( upward arrow) or alkalosis ( downward arrow) and A(tot):hyperproteinemic acidosis ( upward arrow) or hypoproteinemic alkalosis ( downward arrow) were varied and the sum of the buffer bases (BB) was always equal to the SID. All changes and hence BE were also equal, providing that A(tot) was normal. This was not the case, however, if A(tot) was outside the normal range, when BE was then the difference from the normal BB at the respective reference point. Whereas the deviation of the measured pCO(2) was acceptable (1.74+/-0.86 mmHg), this was not the case for the SID (-6.18+/-3.58 mmol/l) calculated from the measured ion concentrations (Na, K, Ca, Cl). Despite controversial discussions, both concepts are much closer than might be expected. Whereas in the Stewart approach the focus of analysis is on plasma, with the Siggaard-Andersen approach it is on blood. Hence, a combined analysis of the blood gases (pH, pCO(2), pO(2), sO(2), cHb, BE) and of the strong ion gap (SIG

  19. Mapping Hurricane Rita inland storm tide

    Science.gov (United States)

    Berenbrock, Charles; Mason, Jr., Robert R.; Blanchard, Stephen F.; Simonovic, Slobodan P.

    2009-01-01

    Flood-inundation data are most useful for decision makers when presented in the context of maps of effected communities and (or) areas. But because the data are scarce and rarely cover the full extent of the flooding, interpolation and extrapolation of the information are needed. Many geographic information systems (GIS) provide various interpolation tools, but these tools often ignore the effects of the topographic and hydraulic features that influence flooding. A barrier mapping method was developed to improve maps of storm tide produced by Hurricane Rita. Maps were developed for the maximum storm tide and at 3-hour intervals from midnight (0000 hour) through noon (1200 hour) on September 24, 2005. The improved maps depict storm-tide elevations and the extent of flooding. The extent of storm-tide inundation from the improved maximum storm-tide map was compared to the extent of flood-inundation from a map prepared by the Federal Emergency Management Agency (FEMA). The boundaries from these two maps generally compared quite well especially along the Calcasieu River. Also a cross-section profile that parallels the Louisiana coast was developed from the maximum storm-tide map and included FEMA high-water marks.

  20. Targeting NF-κB RelA/p65 phosphorylation overcomes RITA resistance.

    Science.gov (United States)

    Bu, Yiwen; Cai, Guoshuai; Shen, Yi; Huang, Chenfei; Zeng, Xi; Cao, Yu; Cai, Chuan; Wang, Yuhong; Huang, Dan; Liao, Duan-Fang; Cao, Deliang

    2016-12-28

    Inactivation of p53 occurs frequently in various cancers. RITA is a promising anticancer small molecule that dissociates p53-MDM2 interaction, reactivates p53 and induces exclusive apoptosis in cancer cells, but acquired RITA resistance remains a major drawback. This study found that the site-differential phosphorylation of nuclear factor-κB (NF-κB) RelA/p65 creates a barcode for RITA chemosensitivity in cancer cells. In naïve MCF7 and HCT116 cells where RITA triggered vast apoptosis, phosphorylation of RelA/p65 increased at Ser536, but decreased at Ser276 and Ser468; oppositely, in RITA-resistant cells, RelA/p65 phosphorylation decreased at Ser536, but increased at Ser276 and Ser468. A phosphomimetic mutation at Ser536 (p65/S536D) or silencing of endogenous RelA/p65 resensitized the RITA-resistant cells to RITA while the phosphomimetic mutant at Ser276 (p65/S276D) led to RITA resistance of naïve cells. In mouse xenografts, intratumoral delivery of the phosphomimetic p65/S536D mutant increased the antitumor activity of RITA. Furthermore, in the RITA-resistant cells ATP-binding cassette transporter ABCC6 was upregulated, and silencing of ABCC6 expression in these cells restored RITA sensitivity. In the naïve cells, ABCC6 delivery led to RITA resistance and blockage of p65/S536D mutant-induced RITA sensitivity. Taken together, these data suggest that the site-differential phosphorylation of RelA/p65 modulates RITA sensitivity in cancer cells, which may provide an avenue to manipulate RITA resistance. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  1. Improved dynamic equations for the generally configured Stewart platform manipulator

    International Nuclear Information System (INIS)

    Pedrammehr, Siamak; Mahboubkhah, Mehran; Khani, Navid

    2012-01-01

    In this paper, a Newton-Euler approach is utilized to generate the improved dynamic equations of the generally configured Stewart platform. Using the kinematic model of the universal joint, the rotational degree of freedom of the pods around the axial direction is taken into account in the formulation. The justifiable direction of the reaction moment on each pod is specified and considered in deriving the dynamic equations. Considering the theorem of parallel axes, the inertia tensors for different elements of the manipulator are obtained in this study. From a theoretical point, the improved formulation is more accurate in comparison with previous ones, and the necessity of the improvement is clear evident from significant differences in the simulation results for the improved model and the model without improvement. In addition to more feasibility of the structure and higher accuracy, the model is highly compatible with computer arithmetic and suitable for online applications for loop control problems in hardware

  2. John Stewart Bell and twentieth century physics vision and integrity

    CERN Document Server

    Whitaker, Andrew

    2016-01-01

    John Stewart Bell (1928-1990) was one of the most important figures in twentieth-century physics, famous for his work on the fundamental aspects of the century's most important theory, quantum mechanics. While the debate over quantum theory between the supremely famous physicists, Albert Einstein and Niels Bohr, appeared to have become sterile in the 1930s, Bell was able to revive it and to make crucial advances - Bell's Theorem or Bell's Inequalities. He was able to demonstrate a contradiction between quantum theory and essential elements of pre-quantum theory - locality and causality. The book gives a non-mathematical account of Bell's relatively impoverished upbringing in Belfast and his education. It describes his major contributions to quantum theory, but also his important work in the physics of accelerators, and nuclear and elementary particle physics.

  3. Added flexibility in triple axis spectrometers: The two RITAs at Risø

    DEFF Research Database (Denmark)

    Lefmann, K.; McMorrow, D.F.; Rønnow, H.M.

    2000-01-01

    The cold-neutron triple-axis spectrometer RITA-I at Rise has been operational for about three years, and in the near future an improved version, RITA-2 will replace the existing triple-axis instrument TAS7. We review the performance of RITA-1 and the operation modes of its flexible secondary...... spectrometer, giving examples of a few key experiments, and describe the software developed for running it. Further, the design of the new RITA-2 instrument is presented. The two RITA spectrometers are compared with their sister instrument SPINS at NIST and with similar instruments planned elsewhere. (C) 2000...

  4. Effectiveness of the Stewart Method in the Evaluation of Blood Gas Parameters.

    Science.gov (United States)

    Gezer, Mustafa; Bulucu, Fatih; Ozturk, Kadir; Kilic, Selim; Kaldirim, Umit; Eyi, Yusuf Emrah

    2015-03-01

    In 1981, Peter A. Stewart published a paper describing his concept for employing Strong Ion Difference. In this study we compared the HCO3 levels and Anion Gap (AG) calculated using the classic method and the Stewart method. Four hundred nine (409) arterial blood gases of 90 patients were collected retrospectively. Some were obtained from the same patients in different times and conditions. All blood samples were evaluated using the same device (ABL 800 Blood Gas Analyzer). HCO3 level and AG were calculated using the Stewart method via the website AcidBase.org. HCO3 levels, AG and strong ion difference (SID) were calculated using the Stewart method, incorporating the parameters of age, serum lactate, glucose, sodium, and pH, etc. According to classic method, the levels of HCO3 and AG were 22.4±7.2 mEq/L and 20.1±4.1 mEq/L respectively. According to Stewart method, the levels of HCO3 and AG were 22.6±7.4 and 19.9±4.5 mEq/L respectively. There was strong correlation between the classic method and the Stewart method for calculating HCO3 and AG. The Stewart method may be more effective in the evaluation of complex metabolic acidosis.

  5. Simulations and experiments on RITA-2 at PSI

    International Nuclear Information System (INIS)

    Klausen, S.N.; Lefmann, K.; McMorrow, D.F.; Altorfer, F.; Janssen, S.; Luethy, M.

    2002-01-01

    The cold-neutron triple-axis spectrometer RITA-2 designed and built at Riso National Laboratory was installed at the neutron source SINQ at Paul Scherrer Institute in April/May 2001. In connection with the installation of RITA-2, computer simulations were performed using the neutron ray-tracing package McStas. The simulation results are compared to real experimental results obtained with a powder sample. Especially, the flux at the sample position and the resolution function of the spectrometer are investigated. (orig.)

  6. Ambient Assisted Living and ageing: preliminary results of RITA project.

    Science.gov (United States)

    Aquilano, Michela; Cavallo, Filippo; Bonaccorsi, Manuele; Esposito, Raffaele; Rovini, Erika; Filippi, Massimo; Esposito, Dario; Dario, Paolo; Carrozza, Maria Chiara

    2012-01-01

    The ageing of population is a social phenomenon that most of worldwide countries are facing. They are, and will be even more in the future, indeed trying to find solutions for improving quality of life of their elderly citizens. The project RITA wants to demonstrate that an update of the current socio-medical services with an Ambient Assisted Living (AAL) approach could improve the service efficiency and the quality of life of both elderly and caregiver. This paper presents the preliminary results obtained in RITA.

  7. Simulations and experiments on RITA-2 at PSI

    Science.gov (United States)

    Klausen, S. N.; Lefmann, K.; McMorrow, D. F.; Altorfer, F.; Janssen, S.; Lüthy, M.

    The cold-neutron triple-axis spectrometer RITA-2 designed and built at Riso National Laboratory was installed at the neutron source SINQ at Paul Scherrer Institute in April/May 2001. In connection with the installation of RITA-2, computer simulations were performed using the neutron ray-tracing package McStas. The simulation results are compared to real experimental results obtained with a powder sample. Especially, the flux at the sample position and the resolution function of the spectrometer are investigated.

  8. RITA inhibits growth of human hepatocellular carcinoma through induction of apoptosis.

    Science.gov (United States)

    Wang, Haihe; Chen, Guofu; Wang, Hongzhi; Liu, Chunbo

    2013-01-01

    RBP-J-interacting and tubulin-associated (RITA) is a novel RBP-J-interacting protein that downregulates Notch-mediated transcription. The current study focuses on the antitumor effect of RITA in human hepatocellular carcinoma (HCC) and aims to explore its molecular mechanism. Thirty paired HCC and adjacent non-tumoral liver samples were analyzed by real-time quantitative reverse transcriptase polymerase chain reaction (qRT-PCR). RITA overexpression was induced by transfection of a pcDNA3.1-Flag-RITA plasmid into HepG2 cells. RITA knockdown was achieved by siRNA transfection. mRNA and protein expression of target genes were quantified by qRT-PCR and Western blotting, respectively. Cell proliferation and apoptosis were measured using MTT assay and flow cytometry. Our results demonstrate that adjacent nontumoral liver samples exhibited increased RITA expression compared to HCC tissues (p RITA levels were associated with tumor differentiation status. Overexpression of RITA suppressed cell proliferation and promoted early apoptosis, while its silencing promoted cell growth dramatically (p RITA overexpression upregulated p53 and reduced cyclin E levels, whereas silencing of RITA had the opposite effect on p53 and cyclin E expression. Our in vitro results represent the first evidence that RITA might suppress tumor growth and induce apoptosis in HCCs, and may be a potent antitumoral agent for HCC treatment that deserves further exploration.

  9. Deficiency of RITA results in multiple mitotic defects by affecting microtubule dynamics.

    Science.gov (United States)

    Steinhäuser, K; Klöble, P; Kreis, N-N; Ritter, A; Friemel, A; Roth, S; Reichel, J M; Michaelis, J; Rieger, M A; Louwen, F; Oswald, F; Yuan, J

    2017-04-01

    Deregulation of mitotic microtubule (MT) dynamics results in defective spindle assembly and chromosome missegregation, leading further to chromosome instability, a hallmark of tumor cells. RBP-J interacting and tubulin-associated protein (RITA) has been identified as a negative regulator of the Notch signaling pathway. Intriguingly, deregulated RITA is involved in primary hepatocellular carcinoma and other malignant entities. We were interested in the potential molecular mechanisms behind its involvement. We show here that RITA binds to tubulin and localizes to various mitotic MT structures. RITA coats MTs and affects their structures in vitro as well as in vivo. Tumor cell lines deficient of RITA display increased acetylated α-tubulin, enhanced MT stability and reduced MT dynamics, accompanied by multiple mitotic defects, including chromosome misalignment and segregation errors. Re-expression of wild-type RITA, but not RITA Δtub ineffectively binding to tubulin, restores the phenotypes, suggesting that the role of RITA in MT modulation is mediated via its interaction with tubulin. Mechanistically, RITA interacts with tubulin/histone deacetylase 6 (HDAC6) and its suppression decreases the binding of the deacetylase HDAC6 to tubulin/MTs. Furthermore, the mitotic defects and increased MT stability are also observed in RITA -/- mouse embryonic fibroblasts. RITA has thus a novel role in modulating MT dynamics and its deregulation results in erroneous chromosome segregation, one of the major reasons for chromosome instability in tumor cells.

  10. Annäherung Approaching

    Directory of Open Access Journals (Sweden)

    Carola Hilmes

    2007-03-01

    Full Text Available Das von Stefan Moses zusammengestellte „Bilderbuch“ zeigt Fotos von Ilse Aichinger. Sie selbst kommt durch eine Reihe von Geschichten und Gedichten zu Wort. In diesen intimen Dialog werden auch die Leser/-innen einbezogen. Das ermöglicht Annäherung.This “Picture Book”, compiled by Stefan Moses, displays photographs of Ilse Aichinger. She is also given voice through a series of stories and poems. The reader is also drawn into this intimate dialogue, thus making it possible for image, text, and reader to converge.

  11. Santa Rita Experimental Range digital database: user's guide

    Science.gov (United States)

    Mitchel P. McClaran; Deborah L. Angell; Craig Wissler

    2002-01-01

    Long-term measurements and repeat photograph collections have been collected in a systematic manner on the approximately 21,000 ha Santa Rita Experimental Range (SRER) since its establishment in 1903. This research facility, located in the Desert Grassland vegetation of southern Arizona, was administered by the U.S. Department of Agriculture until 1988, when it was...

  12. Swamp tours in Louisiana post Hurricane Katrina and Hurricane Rita

    Science.gov (United States)

    Dawn J. Schaffer; Craig A. Miller

    2007-01-01

    Hurricanes Katrina and Rita made landfall in southern Louisiana during August and September 2005. Prior to these storms, swamp tours were a growing sector of nature-based tourism that entertained visitors while teaching about local flora, fauna, and culture. This study determined post-hurricane operating status of tours, damage sustained, and repairs made. Differences...

  13. Sir John and Lady Rita Cornforth: a distinguished chemical partnership.

    Science.gov (United States)

    Purchase, Rupert; Hanson, James R

    2015-01-01

    This review describes the life of Sir John Cornforth AC CBE FRS, who was awarded the Nobel Prize for Chemistry in 1975. It covers his early life in Australia, his work in Oxford, the National Institute for Medical Research, the Milstead Laboratory of Chemical Enzymology and the University of Sussex, together with the contributions made by his wife, Lady Rita Cornforth.

  14. Resilience of Professional Counselors Following Hurricanes Katrina and Rita

    Science.gov (United States)

    Lambert, Simone F.; Lawson, Gerard

    2013-01-01

    Professional counselors who provided services to those affected by Hurricanes Katrina and Rita completed the K6+ (screen for severe mental illness), the Posttraumatic Growth Inventory, and the Professional Quality of Life Scale. Results indicated that participants who survived the hurricanes had higher levels of posttraumatic growth than…

  15. Vibration Isolation and Trajectory Following Control of a Cable Suspended Stewart Platform

    Directory of Open Access Journals (Sweden)

    Xuechao Duan

    2016-10-01

    Full Text Available To achieve high-quality vibration isolation and trajectory following control of a cable driven parallel robot based Stewart platform in the five hundred meter aperture spherical radio telescope (FAST design, the integrated dynamic model of the Stewart platform including the electric cylinder is established in this paper, the globally feedback linearization of the dynamic model is implemented based on the control law partitioning approach. To overcome the disadvantages of the external disturbance on the base and unmodeled flexibility of the mechanism, a PID (Proportional-Derivative-Integral controller with base acceleration feedforward is designed in the operational space of the Stewart platform. Experiments of the vibration isolation and trajectory following control of the cable suspended Stewart platform with presence of the base disturbance is carried out. The experimental results show that the presented control scheme has the advantage of stable dynamics, high accuracy and strong robustness.

  16. A short remark on Stewart 1962 variational principle for laminar flow in a uniform duct

    Directory of Open Access Journals (Sweden)

    Liu Hong-Yan

    2016-01-01

    Full Text Available This paper concludes that Stewart 1962 variational principle for laminar flow in a uniform duct is for a differential-difference. Some generalized variational principles are elucidated with or without Stewart’s discrete treatment.

  17. Analysis of the interaction between human RITA and Drosophila Suppressor of Hairless.

    Science.gov (United States)

    Brockmann, Birgit; Mastel, Helena; Oswald, Franz; Maier, Dieter

    2014-12-01

    Notch signalling mediates intercellular communication, which is effected by the transcription factor CSL, an acronym for vertebrate CBF1/RBP-J, Drosophila Suppressor of Hairless [Su(H)] and C. elegans Lag1. Nuclear import of CBF1/RBP-J depends on co-activators and co-repressors, whereas the export relies on RITA. RITA is a tubulin and CBF1/RBP-J binding protein acting as a negative regulator of Notch signalling in vertebrates. RITA protein is highly conserved in eumatazoa, but no Drosophila homologue was yet identified. In this work, the activity of human RITA in the fly was addressed. To this end, we generated transgenic flies that allow a tissue specific induction of human RITA, which was demonstrated by Western blotting and in fly tissues. Unexpectedly, overexpression of RITA during fly development had little phenotypic consequences, even when overexpressed simultaneously with either Su(H) or the Notch antagonist Hairless. We demonstrate the in vivo binding of human RITA to Su(H) and to tubulin by co-immune precipitation. Moreover, RITA and tubulin co-localized to some degree in several Drosophila tissues. Overall our data show that human RITA, albeit binding to Drosophila Su(H) and tubulin, cannot influence the Notch signalling pathway in the fly, suggesting that a nuclear export mechanism of Su(H), if existent in Drosophila, does not depend on RITA. © 2015 The Authors.

  18. Views of the extravehicular activity of Astronaut Stewart during STS 41-B

    Science.gov (United States)

    1984-01-01

    Close up frontal view of Astronaut Robert L. Stewart, mission specialist, as he participates in a extravehicular activity (EVA), a few meters away from the cabin of the shuttle Challenger. The open payload bay is reflected in his helmet visor as he faces the camera. Stewart is wearing the extravehicular mobility unit (EMU) and one of the manned maneuvering units (MMU) developed for this mission.

  19. Surface ultrastructure of the gill filaments and the secondary lamellae of the catfish, Rita rita, and the carp, Cirrhinus mrigala.

    Science.gov (United States)

    Kumari, Usha; Mittal, Swati; Mittal, Ajay Kumar

    2012-04-01

    Surface ultrastructures of gill filaments and secondary lamellae of Rita rita and Cirrhinus mrigala, inhabiting different ecological habitat, were investigated to unravel adaptive modifications. R. rita is a sluggish, bottom dwelling carnivorous catfish, which inhabits regions of river with accumulations of dirty water. It retains its viability for long time if taken out of water. C. mrigala is an active bottom dwelling Indian major carp, which lives in relatively clean water and dies shortly after taken out of water. In R. rita, gill septa between gill filaments are reduced. Microridges on epithelial cells covering gill filaments are often continuous and arranged concentrically. Secondary lamellae are extensive. The epithelium appears corrugated, show irregular elevations and shallow depressions, and microridges on epithelial cells appear fragmented. In C. mrigala, in contrast, the gill septa are extensive. Microridges on epithelial cells covering gill filaments are fragmented. Secondary lamellae are less extensive. The epithelium appears smooth and microridges on epithelial cells are relatively inconspicuous. These differences have been considered adaptive modification in relation to habit and ecological niches inhabited by two fish species. Presence of mucous goblet cells on gill filaments is discussed in relation to their functions including precipitation of the sediments and preventing clogging of gill filaments. Infrequent mucous goblet cells in the epithelium of secondary lamellae in two fish species are considered an adaptation, minimizing thickness of the epithelium to reduce barrier between blood and water for favoring gasses exchange with increased efficiency. Copyright © 2011 Wiley-Liss, Inc.

  20. Serous goblet cells: the protein secreting cells in the oral cavity of a catfish, Rita rita (Hamilton, 1822) (Bagridae, Siluriformes).

    Science.gov (United States)

    Yashpal, Madhu; Mittal, Ajay Kumar

    2014-02-01

    Serous goblet cells in the oral epithelium of Rita rita are characterized by the presence of distinct eosinophilic granules occupying large parts of the cytoplasm. In R. rita, a range of histochemical results reveal that these cells are involved in proteinaceous secretions, and thus likely contribute to various functions analogous to those of mammalian saliva. The secretions of these cells have also been associated with specific functions and are discussed in relation to their physiological importance with special reference to their roles in lubrication, alteration in viscosity, various functions of mucus such as handling, maneuvering and driving of food items toward the esophagus, maintaining taste sensitivity and protection of the oral epithelium. In addition, the serous goblet cells may also be considered as the primary defensive cell of the oral epithelium of R. rita. The results significantly add to very limited set of literature on the serous goblet cells and provide noteworthy information on the mucous secretions in the oral cavity of fish. Copyright © 2013 Elsevier Ltd. All rights reserved.

  1. [Anne Arold. Kontrastive Analyse...] / Paul Alvre

    Index Scriptorium Estoniae

    Alvre, Paul, 1921-2008

    2001-01-01

    Arvustus: Arold, Anne. Kontrastive analyse der Wortbildungsmuster im Deutschen und im Estnischen (am Beispiel der Aussehensadjektive). Tartu, 2000. (Dissertationes philologiae germanicae Universitatis Tartuensis)

  2. Pyrite-coated granite cobbles at Lee Bay, Stewart Island

    International Nuclear Information System (INIS)

    Brathwaite, R.L.; Skinner, D.N.B.; Faure, K.; Edwards, E.

    2014-01-01

    On the west side of Lee Bay on the northeast coast of Stewart Island, ventifact cobbles of pyrite-coated granite occur on the beach near the high tide mark and appear to be derived from a sand-cemented gravel deposit that forms a low bank at the back of the beach. The pyrite coat (up to 1 mm thick) completely covers the granitic cobbles and is zoned, with an inner zone of fine-grained colloform pyrite and an outer framboidal zone. Framboidal pyrite is typically formed in anoxic sedimentary environments. Subrounded grains of hematite, ilmenite with hematite blebs, magnetite, feldspar, biotite, quartz and zircon are present in the outer framboidal zone, with some ilmenite and hematite grains being partially replaced by pyrite. The assemblage of ilmenite-hematite-magnetite-biotite-zircon is similar both in mineralogy and size range to that found in heavy mineral beach sands. Sulphur isotope values of the pyrite coat are consistent with formation of the pyrite by microbial sulphate reduction of seawater sulphate. The framboidal texture together with the presence of grains of beach sand in the pyrite coating indicate that it was deposited in a low-temperature sedimentary environment. (author)

  3. Assessment of acid-base balance. Stewart's approach.

    Science.gov (United States)

    Fores-Novales, B; Diez-Fores, P; Aguilera-Celorrio, L J

    2016-04-01

    The study of acid-base equilibrium, its regulation and its interpretation have been a source of debate since the beginning of 20th century. Most accepted and commonly used analyses are based on pH, a notion first introduced by Sorensen in 1909, and on the Henderson-Hasselbalch equation (1916). Since then new concepts have been development in order to complete and make easier the understanding of acid-base disorders. In the early 1980's Peter Stewart brought the traditional interpretation of acid-base disturbances into question and proposed a new method. This innovative approach seems more suitable for studying acid-base abnormalities in critically ill patients. The aim of this paper is to update acid-base concepts, methods, limitations and applications. Copyright © 2015 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

  4. Mary Anne Chambers | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    A former Member of Provincial Parliament, Mary Anne served as Minister of Training, Colleges and Universities, and Minister of Children and Youth Services in the Government of Ontario. She is also a former senior vice-president of Scotiabank. A graduate of the University of Toronto, Mary Anne has received honorary ...

  5. Theorethical principles of fluid managment according to physicochemical Stewart approach.

    Science.gov (United States)

    Smuszkiewicz, Piotr; Szrama, Jakub

    2013-01-01

    Interpreting acid base disturbances according to the physicochemical Stewart approach allows the cause of such abnormalities to be discovered. This method is based on three independent variables: SID (strong ion difference), mainly sodium and chloride; weak acids concentration - Atot, mainly albumins and phosphate; and carbon dioxide tension - pCO₂. These three independent variables are responsible for the change of water dissociation and for the change in H+ concentration and, consequently, the change in serum pH value. The SID value of the fluids administered to a patient is responsible for the change of serum SID value and therefore causes a change in the patient's acid base status. During the infusion of a given fluid, the SID value of the serum becomes closer to the SID value of that fluid; on the other hand, the infusion causes a decrease in Atot concentration. In order to avoid acid base disturbances connected with fluid administration, the SID value of fluids being administered should be greater than 0 and lower then the serum SID. It has been suggested that fluids should be given of which the SID value is as close as possible to the actual serum HCO₃ concentration. Knowing the SID value of the fluid administered, and the serum HCO₃ concentration, one can expect a change of serum pH after a fluid infusion. Administering a fluid with a SID greater than the HCO₃ concentration causes a pH increase towards alkalosis. Likewise, administering a a fluid with a SID lower than the HCO₃ concentration causes a pH decrease towards acidosis. It seems that knowledge of the electrolyte concentration and the SID value of an administered fluid is an important factor regarding acid base disturbances.

  6. Combined VLF and VHF lightning observations of Hurricane Rita landfall

    Science.gov (United States)

    Henderson, B. G.; Suszcynsky, D. M.; Wiens, K. C.; Hamlin, T.; Jeffery, C. A.; Orville, R. E.

    2009-12-01

    Hurricane Rita displayed abundant lightning in its northern eyewall as it made landfall at 0740 UTC 24 Sep 2005 near the Texas/Louisiana border. For this work, we combined VHF and VLF lightning data from Hurricane Rita, along with radar observations from Gulf Coast WSR-88D stations, for the purpose of demonstrating the combined utility of these two spectral regions for hurricane lightning monitoring. Lightning is a direct consequence of the electrification and breakdown processes that take place during the convective stages of thunderstorm development. As Rita approached the Gulf coast, the VHF lightning emissions were distinctly periodic with a period of 1.5 to 2 hours, which is consistent with the rotational period of hurricanes. VLF lightning emissions, measured by LASA and NLDN, were present in some of these VHF bursts but not all of them. At landfall, there was a significant increase in lightning emissions, accompanied by a significant convective surge observed in radar. Furthermore, VLF and VHF lightning source heights clearly increase as a function of time. The evolution of the IC/CG ratio is consistent with that seen in thunderstorms, showing a dominance of IC activity during storm development, followed by an increase in CG activity at the storm’s peak. The periodic VHF lightning events are correlated with increases in convective growth (quantified by the volume of radar echo >40 dB) above 7 km altitude. VLF can discriminate between lightning types, and in the LASA data, Rita landfall lightning activity was dominated by Narrow Bi-polar Events (NBEs)—high-energy, high-altitude, compact intra-cloud discharges. The opportunity to locate NBE lightning sources in altitude may be particularly useful in quantifying the vertical extent (strength) of the convective development and in possibly deducing vertical charge distributions.

  7. Lightning and radar observations of hurricane Rita landfall

    Energy Technology Data Exchange (ETDEWEB)

    Henderson, Bradley G [Los Alamos National Laboratory; Suszcynsky, David M [Los Alamos National Laboratory; Hamlin, Timothy E [Los Alamos National Laboratory; Jeffery, C A [Los Alamos National Laboratory; Wiens, Kyle C [TEXAS TECH U.; Orville, R E [TEXAS A& M

    2009-01-01

    Los Alamos National Laboratory (LANL) owns and operates an array of Very-Low Frequency (VLF) sensors that measure the Radio-Frequency (RF) waveforms emitted by Cloud-to-Ground (CG) and InCloud (IC) lightning. This array, the Los Alamos Sferic Array (LASA), has approximately 15 sensors concentrated in the Great Plains and Florida, which detect electric field changes in a bandwidth from 200 Hz to 500 kHz (Smith et al., 2002). Recently, LANL has begun development of a new dual-band RF sensor array that includes the Very-High Frequency (VHF) band as well as the VLF. Whereas VLF lightning emissions can be used to deduce physical parameters such as lightning type and peak current, VHF emissions can be used to perform precise 3d mapping of individual radiation sources, which can number in the thousands for a typical CG flash. These new dual-band sensors will be used to monitor lightning activity in hurricanes in an effort to better predict intensification cycles. Although the new LANL dual-band array is not yet operational, we have begun initial work utilizing both VLF and VHF lightning data to monitor hurricane evolution. In this paper, we present the temporal evolution of Rita's landfall using VLF and VHF lightning data, and also WSR-88D radar. At landfall, Rita's northern eyewall experienced strong updrafts and significant lightning activity that appear to mark a transition between oceanic hurricane dynamics and continental thunderstorm dynamics. In section 2, we give a brief overview of Hurricane Rita, including its development as a hurricane and its lightning history. In the following section, we present WSR-88D data of Rita's landfall, including reflectivity images and temporal variation. In section 4, we present both VHF and VLF lightning data, overplotted on radar reflectivity images. Finally, we discuss our observations, including a comparison to previous studies and a brief conclusion.

  8. Development of Miniature Stewart Platform Using TiNiCu Shape-Memory-Alloy Actuators

    Directory of Open Access Journals (Sweden)

    Alaa AbuZaiter

    2015-01-01

    Full Text Available A Stewart platform is a parallel manipulator robot that is able to perform three linear movements, lateral, longitudinal, and vertical, and three rotations, pitch, yaw, and roll. This paper reports a 30 mm × 30 mm × 34 mm miniscale Stewart platform using TiNiCu shape-memory-alloy (SMA actuators. The proposed Stewart platform possesses various advantages, such as large actuation force and high robustness with a simple mechanical structure. This Stewart platform uses four SMA actuators and four bias springs and performs a linear z-axis movement and tilting motions. The SMA actuators are activated by passing a current through the SMA wires using a heating circuit that generates a pulse width modulation (PWM signal. This signal is varied to control the level of the displacement and tilting angle of the platform. The tilting direction depends on the SMA actuator that is activated, while all four SMA actuators are activated to achieve the linear z-axis movement. Each SMA actuator exerts a maximum force of 0.6 N at PWM duty cycle of 100%. The fabricated miniature Stewart platform yields a full actuation of 12 mm in the z-axis at 55°C, with a maximum tilting angle of 30° in 4 s.

  9. Investigation on active vibration isolation of a Stewart platform with piezoelectric actuators

    Science.gov (United States)

    Wang, Chaoxin; Xie, Xiling; Chen, Yanhao; Zhang, Zhiyi

    2016-11-01

    A Stewart platform with piezoelectric actuators is presented for micro-vibration isolation. The Jacobi matrix of the Stewart platform, which reveals the relationship between the position/pointing of the payload and the extensions of the six struts, is derived by kinematic analysis. The dynamic model of the Stewart platform is established by the FRF (frequency response function) synthesis method. In the active control loop, the direct feedback of integrated forces is combined with the FxLMS based adaptive feedback to dampen vibration of inherent modes and suppress transmission of periodic vibrations. Numerical simulations were conducted to prove vibration isolation performance of the Stewart platform under random and periodical disturbances, respectively. In the experiment, the output consistencies of the six piezoelectric actuators were measured at first and the theoretical Jacobi matrix as well as the feedback gain of each piezoelectric actuator was subsequently modified according to the measured consistencies. The direct feedback loop was adjusted to achieve sufficient active damping and the FxLMS based adaptive feedback control was adopted to suppress vibration transmission in the six struts. Experimental results have demonstrated that the Stewart platform can achieve 30 dB attenuation of periodical disturbances and 10-20 dB attenuation of random disturbances in the frequency range of 5-200 Hz.

  10. 75 FR 7467 - Gary E. Hall and Rita C. Hall; Notice of Application Accepted for Filing With the Commision...

    Science.gov (United States)

    2010-02-19

    ... Rita C. Hall; Notice of Application Accepted for Filing With the Commision, Soliciting Motions To.... Project No.: 13652-000. c. Date filed: January 11, 2010. d. Applicant: Gary E. Hall and Rita C. Hall. e... Policies Act of 1978, 16 U.S.C. 2705, 2708. h. Applicant Contact: Mr. Gary E. Hall and Ms. Rita C. Hall, P...

  11. RITA plus 3-MA overcomes chemoresistance of head and neck cancer cells via dual inhibition of autophagy and antioxidant systems

    Directory of Open Access Journals (Sweden)

    Daiha Shin

    2017-10-01

    Condensed abstract: This study revealed a novel RITA resistant mechanism associated with the sustained induction of autophagy, p62 overexpression, and Keap1-Nrf2 antioxidant system activation. The combined treatment of RITA with the autophagy inhibitor 3-methyladenine overcomes RITA resistance via dual inhibition of autophagy and antioxidant systems in vitro and in vivo.

  12. POTENSI BAKTERI ENDOFIT DALAM MENEKAN PENYAKIT LAYU STEWART (PANTOEA STEWARTII SUBSP. STEWARTII PADA TANAMAN JAGUNG

    Directory of Open Access Journals (Sweden)

    Haliatur Rahma

    2017-04-01

    Full Text Available Potential of endophytic bacteria to control stewart wilt disease (Pantoea stewartii subsp. stewartii in maize. The purpose of this study was to explore endophytic bacteria from seedling, maize roots and grass roots as well as to test the ability of endophytic bacteria which could potentially suppress stewart wilt disease development in maize. Characterization of endophytic bacteria as biocontrol agents including: do not induce HR on tobacco, synthesize IAA, dissolve phosphate, produce siderophores, and antibiotic to Pantoea stewartii subsp. stewartii (Pnss. The results of research shoed 17 isolates of endophytic bacteria potentially as candidate biocontrol agents. Nine isolates were able to produce IAA, siderofores and phosphatase; two isolates produce IAA and phosphatase; six isolates produce IAA. Six isolates ie: AR1, AJ34, AJ15, AJ19, and AJ14 AN6, can increase maize plant resistance and suppress stewart wilt disease severity with a range of 48.95-55.60%.

  13. On the viability of the truncated Israel–Stewart theory in cosmology

    International Nuclear Information System (INIS)

    Shogin, Dmitry; Amundsen, Per Amund; Hervik, Sigbjørn

    2015-01-01

    We apply the causal Israel–Stewart theory of irreversible thermodynamics to model the matter content of the Universe as a dissipative fluid with bulk and shear viscosity. Along with the full transport equations we consider their widely used truncated version. By implementing a dynamical systems approach to Bianchi type IV and V cosmological models with and without cosmological constant, we determine the future asymptotic states of such Universes and show that the truncated Israel–Stewart theory leads to solutions essentially different from the full theory. The solutions of the truncated theory may also manifest unphysical properties. Finally, we find that in the full theory shear viscosity can give a substantial rise to dissipative fluxes, driving the fluid extremely far from equilibrium, where the linear Israel–Stewart theory ceases to be valid. (paper)

  14. The p53-reactivating small molecule RITA induces senescence in head and neck cancer cells.

    Directory of Open Access Journals (Sweden)

    Hui-Ching Chuang

    Full Text Available TP53 is the most commonly mutated gene in head and neck cancer (HNSCC, with mutations being associated with resistance to conventional therapy. Restoring normal p53 function has previously been investigated via the use of RITA (reactivation of p53 and induction of tumor cell apoptosis, a small molecule that induces a conformational change in p53, leading to activation of its downstream targets. In the current study we found that RITA indeed exerts significant effects in HNSCC cells. However, in this model, we found that a significant outcome of RITA treatment was accelerated senescence. RITA-induced senescence in a variety of p53 backgrounds, including p53 null cells. Also, inhibition of p53 expression did not appear to significantly inhibit RITA-induced senescence. Thus, this phenomenon appears to be partially p53-independent. Additionally, RITA-induced senescence appears to be partially mediated by activation of the DNA damage response and SIRT1 (Silent information regulator T1 inhibition, with a synergistic effect seen by combining either ionizing radiation or SIRT1 inhibition with RITA treatment. These data point toward a novel mechanism of RITA function as well as hint to its possible therapeutic benefit in HNSCC.

  15. How Schools Responded to Student Mental Health Needs Following Hurricanes Katrina and Rita. Fact Sheet

    Science.gov (United States)

    RAND Corporation, 2007

    2007-01-01

    This fact sheet summarizes a study that examined how schools in the U.S. Gulf Coast region perceived the mental health needs of students after Hurricanes Katrina and Rita and how schools responded. According to the report, despite strong initial efforts to support the mental health needs of students displaced by Hurricanes Katrina and Rita, many…

  16. The p53-reactivating small molecule RITA induces senescence in head and neck cancer cells.

    Science.gov (United States)

    Chuang, Hui-Ching; Yang, Liang Peng; Fitzgerald, Alison L; Osman, Abdullah; Woo, Sang Hyeok; Myers, Jeffrey N; Skinner, Heath D

    2014-01-01

    TP53 is the most commonly mutated gene in head and neck cancer (HNSCC), with mutations being associated with resistance to conventional therapy. Restoring normal p53 function has previously been investigated via the use of RITA (reactivation of p53 and induction of tumor cell apoptosis), a small molecule that induces a conformational change in p53, leading to activation of its downstream targets. In the current study we found that RITA indeed exerts significant effects in HNSCC cells. However, in this model, we found that a significant outcome of RITA treatment was accelerated senescence. RITA-induced senescence in a variety of p53 backgrounds, including p53 null cells. Also, inhibition of p53 expression did not appear to significantly inhibit RITA-induced senescence. Thus, this phenomenon appears to be partially p53-independent. Additionally, RITA-induced senescence appears to be partially mediated by activation of the DNA damage response and SIRT1 (Silent information regulator T1) inhibition, with a synergistic effect seen by combining either ionizing radiation or SIRT1 inhibition with RITA treatment. These data point toward a novel mechanism of RITA function as well as hint to its possible therapeutic benefit in HNSCC.

  17. Te Rita Papesch: Case Study of an Exemplary Learner of Maori as an Additional Language

    Science.gov (United States)

    Ratima, Matiu Tai; Papesch, Te Rita

    2014-01-01

    This paper presents a case study of the life experiences of one exemplar adult second language Maori learner--Te Rita Papesch. Te Rita was one of 17 participants who were interviewed as a part of the first author's PhD study which sought to answer the question: what factors lead to the development of proficiency in te reo Maori amongst adult…

  18. 75 FR 14442 - Federal Travel Regulation (FTR); Relocation Allowances-Relocation Income Tax Allowance (RITA) Tables

    Science.gov (United States)

    2010-03-25

    ... GENERAL SERVICES ADMINISTRATION [GSA Bulletin FTR 10-04] Federal Travel Regulation (FTR); Relocation Allowances-- Relocation Income Tax Allowance (RITA) Tables AGENCY: Office of Governmentwide Policy... (73 FR 35952) specifying that GSA would no longer publish the RITA tables found in 41 CFR Part 301-17...

  19. Six-degree-of-freedom active vibration isolation using a Stewart platform mechanism

    Science.gov (United States)

    Geng, Zheng; Haynes, Leonard S.

    1993-01-01

    The design and control problems of a class of multidegree-of-freedom vibration isolation systems (VISs) based on a Stewart platform mechanism are studied. A prototype of a six-degree-of-freedom VIS for precision control of a wide range of space-based structures implemented in Intelligent Automation, Inc. is described. The feasibility of using a Stewart platform to achieve 6-degree-of-freedom vibration control in space applications is shown. A new Terfenol-D actuator characterized by significantly longer stroke than any commercially available Terfenol-D actuator and direct flux and strain sensors integral to the actuator is described.

  20. 78 FR 19362 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel W.L. STEWART III; Invitation...

    Science.gov (United States)

    2013-03-29

    ... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2013 0026] Requested Administrative Waiver of the Coastwise Trade Laws: Vessel W.L. STEWART III; Invitation for Public Comments AGENCY.... STEWART III is: Intended Commercial Use of Vessel: ``Yacht Club Regatta and Sailing Instruction Support...

  1. RITA displays anti-tumor activity in medulloblastomas independent of TP53 status.

    Science.gov (United States)

    Gottlieb, Aline; Althoff, Kristina; Grunewald, Laura; Thor, Theresa; Odersky, Andrea; Schulte, Marc; Deubzer, Hedwig E; Heukamp, Lukas; Eggert, Angelika; Schramm, Alexander; Schulte, Johannes H; Künkele, Annette

    2017-04-25

    Current therapy of medulloblastoma, the most common malignant brain tumor of childhood, achieves 40-70% survival. Secondary chemotherapy resistance contributes to treatment failure, where TP53 pathway dysfunction plays a key role. MDM2 interaction with TP53 leads to its degradation. Reactivating TP53 functionality using small-molecule inhibitors, such as RITA, to disrupt TP53-MDM2 binding may have therapeutic potential. We show here that RITA decreased viability of all 4 analyzed medulloblastoma cell lines, regardless of TP53 functional status. The decrease in cell viability was accompanied in 3 of the 4 medulloblastoma cell lines by accumulation of TP53 protein in the cells and increased CDKN1A expression. RITA treatment in mouse models inhibited medulloblastoma xenograft tumor growth. These data demonstrate that RITA treatment reduces medulloblastoma cell viability in both in vitro and in vivo models, and acts independently of cellular TP53 status, identifying RITA as a potential therapeutic agent to treat medulloblastoma.

  2. Conversacion sobre "Tres tristes tigres". Una entrevista de Rita Guibert (A Conversation about "Three Sad Tigers". An Interview with Rita Guibert)

    Science.gov (United States)

    Cabrera Infante, Guillermo

    1971-01-01

    Interview took place in London, England, on October 5, 1970 between Cuban writer Guillermo Cabrera Infante and journalist Rita Guibert. Special issue dedicated to contemporary Spanish American literature. (DS)

  3. Reactivating p53 and Inducing Tumor Apoptosis (RITA) Enhances the Response of RITA-Sensitive Colorectal Cancer Cells to Chemotherapeutic Agents 5-Fluorouracil and Oxaliplatin.

    Science.gov (United States)

    Wiegering, Armin; Matthes, Niels; Mühling, Bettina; Koospal, Monika; Quenzer, Anne; Peter, Stephanie; Germer, Christoph-Thomas; Linnebacher, Michael; Otto, Christoph

    2017-04-01

    Colorectal carcinoma (CRC) is the most common cancer of the gastrointestinal tract with frequently dysregulated intracellular signaling pathways, including p53 signaling. The mainstay of chemotherapy treatment of CRC is 5-fluorouracil (5FU) and oxaliplatin. The two anticancer drugs mediate their therapeutic effect via DNA damage-triggered signaling. The small molecule reactivating p53 and inducing tumor apoptosis (RITA) is described as an activator of wild-type and reactivator of mutant p53 function, resulting in elevated levels of p53 protein, cell growth arrest, and cell death. Additionally, it has been shown that RITA can induce DNA damage signaling. It is expected that the therapeutic benefits of 5FU and oxaliplatin can be increased by enhancing DNA damage signaling pathways. Therefore, we highlighted the antiproliferative response of RITA alone and in combination with 5FU or oxaliplatin in human CRC cells. A panel of long-term established CRC cell lines (n=9) including p53 wild-type, p53 mutant, and p53 null and primary patient-derived, low-passage cell lines (n=5) with different p53 protein status were used for this study. A substantial number of CRC cells with pronounced sensitivity to RITA (IC 50 RITA appeared independent of p53 status and was associated with an increase in antiproliferative response to 5FU and oxaliplatin, a transcriptional increase of p53 targets p21 and NOXA, and a decrease in MYC mRNA. The effect of RITA as an inducer of DNA damage was shown by a strong elevation of phosphorylated histone variant H2A.X, which was restricted to RITA-sensitive cells. Our data underline the primary effect of RITA, inducing DNA damage, and demonstrate the differential antiproliferative effect of RITA to CRC cells independent of p53 protein status. We found a substantial number of RITA-sensitive CRC cells within both panels of established CRC cell lines and primary patient-derived CRC cell lines (6/14) that provide a rationale for combining RITA with 5FU or

  4. Reactivating p53 and Inducing Tumor Apoptosis (RITA Enhances the Response of RITA-Sensitive Colorectal Cancer Cells to Chemotherapeutic Agents 5-Fluorouracil and Oxaliplatin

    Directory of Open Access Journals (Sweden)

    Armin Wiegering

    2017-04-01

    Full Text Available Colorectal carcinoma (CRC is the most common cancer of the gastrointestinal tract with frequently dysregulated intracellular signaling pathways, including p53 signaling. The mainstay of chemotherapy treatment of CRC is 5-fluorouracil (5FU and oxaliplatin. The two anticancer drugs mediate their therapeutic effect via DNA damage-triggered signaling. The small molecule reactivating p53 and inducing tumor apoptosis (RITA is described as an activator of wild-type and reactivator of mutant p53 function, resulting in elevated levels of p53 protein, cell growth arrest, and cell death. Additionally, it has been shown that RITA can induce DNA damage signaling. It is expected that the therapeutic benefits of 5FU and oxaliplatin can be increased by enhancing DNA damage signaling pathways. Therefore, we highlighted the antiproliferative response of RITA alone and in combination with 5FU or oxaliplatin in human CRC cells. A panel of long-term established CRC cell lines (n = 9 including p53 wild-type, p53 mutant, and p53 null and primary patient-derived, low-passage cell lines (n = 5 with different p53 protein status were used for this study. A substantial number of CRC cells with pronounced sensitivity to RITA (IC50< 3.0 μmol/l were identified within established (4/9 and primary patient-derived (2/5 CRC cell lines harboring wild-type or mutant p53 protein. Sensitivity to RITA appeared independent of p53 status and was associated with an increase in antiproliferative response to 5FU and oxaliplatin, a transcriptional increase of p53 targets p21 and NOXA, and a decrease in MYC mRNA. The effect of RITA as an inducer of DNA damage was shown by a strong elevation of phosphorylated histone variant H2A.X, which was restricted to RITA-sensitive cells. Our data underline the primary effect of RITA, inducing DNA damage, and demonstrate the differential antiproliferative effect of RITA to CRC cells independent of p53 protein status. We found a substantial number

  5. Shelf sediment transport during hurricanes Katrina and Rita

    Science.gov (United States)

    Xu, Kehui; Mickey, Rangley C.; Chen, Qin; Harris, Courtney K.; Hetland, Robert D.; Hu, Kelin; Wang, Jiaze

    2016-05-01

    Hurricanes can greatly modify the sedimentary record, but our coastal scientific community has rather limited capability to predict hurricane-induced sediment deposition. A three-dimensional sediment transport model was developed in the Regional Ocean Modeling System (ROMS) to study seabed erosion and deposition on the Louisiana shelf in response to Hurricanes Katrina and Rita in the year 2005. Sensitivity tests were performed on both erosional and depositional processes for a wide range of erosional rates and settling velocities, and uncertainty analysis was done on critical shear stresses using the polynomial chaos approximation method. A total of 22 model runs were performed in sensitivity and uncertainty tests. Estimated maximum erosional depths were sensitive to the inputs, but horizontal erosional patterns seemed to be controlled mainly by hurricane tracks, wave-current combined shear stresses, seabed grain sizes, and shelf bathymetry. During the passage of two hurricanes, local resuspension and deposition dominated the sediment transport mechanisms. Hurricane Katrina followed a shelf-perpendicular track before making landfall and its energy dissipated rapidly within about 48 h along the eastern Louisiana coast. In contrast, Hurricane Rita followed a more shelf-oblique track and disturbed the seabed extensively during its 84-h passage from the Alabama-Mississippi border to the Louisiana-Texas border. Conditions to either side of Hurricane Rita's storm track differed substantially, with the region to the east having stronger winds, taller waves and thus deeper erosions. This study indicated that major hurricanes can disturb the shelf at centimeter to meter levels. Each of these two hurricanes suspended seabed sediment mass that far exceeded the annual sediment inputs from the Mississippi and Atchafalaya Rivers, but the net transport from shelves to estuaries is yet to be determined. Future studies should focus on the modeling of sediment exchange between

  6. Stewart analysis of apparently normal acid-base state in the critically ill

    NARCIS (Netherlands)

    Moviat, M.; Boogaard, M. van den; Intven, F.; Voort, P. van der; Hoeven, H. van der; Pickkers, P.

    2013-01-01

    PURPOSE: This study aimed to describe Stewart parameters in critically ill patients with an apparently normal acid-base state and to determine the incidence of mixed metabolic acid-base disorders in these patients. MATERIALS AND METHODS: We conducted a prospective, observational multicenter study of

  7. Behavioural modelling using the MOESP algorithm, dynamic neural networks and the Bartels-Stewart algorithm

    NARCIS (Netherlands)

    Schilders, W.H.A.; Meijer, P.B.L.; Ciggaar, E.

    2008-01-01

    In this paper we discuss the use of the state-space modelling MOESP algorithm to generate precise information about the number of neurons and hidden layers in dynamic neural networks developed for the behavioural modelling of electronic circuits. The Bartels–Stewart algorithm is used to transform

  8. 76 FR 33777 - Stewart B. McKinney National Wildlife Refuge, Middlesex County, CT; Comprehensive Conservation...

    Science.gov (United States)

    2011-06-09

    ... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R5-R-2011-N043; BAC-4311-K9-S3] Stewart B. McKinney National Wildlife Refuge, Middlesex County, CT; Comprehensive Conservation Plan and... headquarters located in Middlesex County, CT. This notice complies with our CCP policy to: (1) Advise other...

  9. Model Predictive Controller Combined with LQG Controller and Velocity Feedback to Control the Stewart Platform

    DEFF Research Database (Denmark)

    Nadimi, Esmaeil Sharak; Bak, Thomas; Izadi-Zamanabadi, Roozbeh

    2006-01-01

    The main objective of this paper is to investigate the erformance and applicability of two GPC (generalized predictive control) based control methods on a complete benchmark model of the Stewart platform made in MATLAB V6.5. The first method involves an LQG controller (Linear Quadratic Gaussian...

  10. Relation between coordinate systems describing the dynamics of a loaded Stewart platform

    Science.gov (United States)

    Petrova, V. I.

    2018-05-01

    The paper puts forward formulae for transformation of coordinates in three coordinate frames used for the study of motion of a loaded Stewart platform, which is the central mechanism of the dynamic bench. A new method for finding the law of variation of coordinates is proposed. This method depends on solving the problem-specific system of differential equations.

  11. Pretibial Located Stewart-Treves Syndrome: Uncommon Presentation in a Bulgarian Patient!

    Science.gov (United States)

    Tchernev, Georgi; Yungareva, Irina; Mangarov, Hristo; Stavrov, Konstantin; Lozev, Ilia; Temelkova, Ivanka; Chernin, Svetoslav; Pidakev, Ivan; Tronnier, Michael

    2018-04-15

    The Stewart-Treves syndrome with localisation in the region of the lower extremities is not something unusual as clinical pathology, but the clinical diagnostics is rather difficult, and it can be further complicated maximally because of: the similar locoregional findings in patients with other cutaneous malignancies. Presented is a rare form of an epithelioid variant of the Stewart Treves syndrome in a woman, aged 81, localised in the region of the lower leg and significantly advanced only for 2 months. The diagnosis was confirmed histologically and immunohistochemically. Amputation of the affected extremity was planned. Discussed are important etiopathogenetic aspects regarding the approach in patients with lymphedema and possibility for development of the Stewart Treves syndrome. Analyzing the evidence from the literature worldwide, we concluded that perhaps the only reliable (to some extent) therapeutic option in patients with Stewart Treves Syndrome is 1) the early diagnostics and 2) the following inevitable radical excision or amputation with the maximal field of surgical security in the proximal direction.

  12. THE FEMINISM AND FEMININITY OF ANN VERONICA IN H. G. WELLS' ANN VERONICA

    Directory of Open Access Journals (Sweden)

    Liem Satya Limanta

    2002-01-01

    Full Text Available H.G. Well's Ann Veronica structurally seems to be divided into two parts; the first deals with Ann Veronica's struggle to get equality with men and freedom in most aspects of life, such as in politics, economics, education, and sexuality; the second describes much the other side of her individuality which she cannot deny, namely her femininity, such as her crave for love, marriage, maternity, and beauty. H.G. Wells describes vividly the two elements in Ann Veronica, feminism and femininity. As a feminist, Ann Veronica rebelled against her authoritative Victorian father, who regarded women only as men's property to be protected from the harsh world outside. On the other side, Ann could not deny her being a woman after she fell in love with Capes. Her femininity from the second half of the novel then is explored. Although the novel ends with the depiction of the domestic life of Ann Veronica, it does not mean that the feminism is gone altogether. The key point is that the family life Ann chooses as a `submissive' wife and good mother is her choice. It is very different if it is forced on her to do. Thus, this novel depicts both sides of Ann Veronica, her feminism and her femininity.

  13. Biogas engine performance estimation using ANN

    Directory of Open Access Journals (Sweden)

    Yusuf Kurtgoz

    2017-12-01

    Full Text Available Artificial neural network (ANN method was used to estimate the thermal efficiency (TE, brake specific fuel consumption (BSFC and volumetric efficiency (VE values of a biogas engine with spark ignition at different methane (CH4 ratios and engine load values. For this purpose, the biogas used in the biogas engine was produced by the anaerobic fermentation method from bovine manure and different CH4 contents (51%, 57%, 87% were obtained by purification of CO2 and H2S. The data used in the ANN models were obtained experimentally from a 4-stroke four-cylinder, spark ignition engine, at constant speed for different load and CH4 ratios. Using some of the obtained experimental data, ANN models were developed, and the rest was used to test the developed models. In the ANN models, the CH4 ratio of the fuel, engine load, inlet air temperature (Tin, air fuel ratio and the maximum cylinder pressure are chosen as the input parameters. TE, BSFC and VE are used as the output parameters. Root mean square error (RMSE, mean absolute percentage error (MAPE and correlation coefficient (R performance indicators are used to compare measured and predicted values. It has been shown that ANN models give good results in spark ignition biogas engines with high correlation and low error rates for TE, BSFC and VE values.

  14. Feature Selection and ANN Solar Power Prediction

    Directory of Open Access Journals (Sweden)

    Daniel O’Leary

    2017-01-01

    Full Text Available A novel method of solar power forecasting for individuals and small businesses is developed in this paper based on machine learning, image processing, and acoustic classification techniques. Increases in the production of solar power at the consumer level require automated forecasting systems to minimize loss, cost, and environmental impact for homes and businesses that produce and consume power (prosumers. These new participants in the energy market, prosumers, require new artificial neural network (ANN performance tuning techniques to create accurate ANN forecasts. Input masking, an ANN tuning technique developed for acoustic signal classification and image edge detection, is applied to prosumer solar data to improve prosumer forecast accuracy over traditional macrogrid ANN performance tuning techniques. ANN inputs tailor time-of-day masking based on error clustering in the time domain. Results show an improvement in prediction to target correlation, the R2 value, lowering inaccuracy of sample predictions by 14.4%, with corresponding drops in mean average error of 5.37% and root mean squared error of 6.83%.

  15. An ANN application for water quality forecasting.

    Science.gov (United States)

    Palani, Sundarambal; Liong, Shie-Yui; Tkalich, Pavel

    2008-09-01

    Rapid urban and coastal developments often witness deterioration of regional seawater quality. As part of the management process, it is important to assess the baseline characteristics of the marine environment so that sustainable development can be pursued. In this study, artificial neural networks (ANNs) were used to predict and forecast quantitative characteristics of water bodies. The true power and advantage of this method lie in its ability to (1) represent both linear and non-linear relationships and (2) learn these relationships directly from the data being modeled. The study focuses on Singapore coastal waters. The ANN model is built for quick assessment and forecasting of selected water quality variables at any location in the domain of interest. Respective variables measured at other locations serve as the input parameters. The variables of interest are salinity, temperature, dissolved oxygen, and chlorophyll-alpha. A time lag up to 2Delta(t) appeared to suffice to yield good simulation results. To validate the performance of the trained ANN, it was applied to an unseen data set from a station in the region. The results show the ANN's great potential to simulate water quality variables. Simulation accuracy, measured in the Nash-Sutcliffe coefficient of efficiency (R(2)), ranged from 0.8 to 0.9 for the training and overfitting test data. Thus, a trained ANN model may potentially provide simulated values for desired locations at which measured data are unavailable yet required for water quality models.

  16. Prognostic impact of RITA expression in patients with anal squamous cell carcinoma treated with chemoradiotherapy.

    Science.gov (United States)

    Rödel, Franz; Steinhäuser, Kerstin; Kreis, Nina-Naomi; Friemel, Alexandra; Martin, Daniel; Wieland, Ulrike; Rave-Fränk, Margret; Balermpas, Panagiotis; Fokas, Emmanouil; Louwen, Frank; Rödel, Claus; Yuan, Juping

    2018-02-01

    RBP-J interacting and tubulin-associated protein (RITA) has been identified as a negative regulator of the Notch signalling pathway and its deregulation is involved in the pathogenesis of several tumour entities. RITA's impact on the response of anal squamous cell carcinoma (SCC) to anticancer treatment, however, remains elusive. In our retrospective study immunohistochemical evaluation of RITA was performed on 140 pre-treatment specimens and was correlated with clinical and histopathologic characteristics and clinical endpoints cumulative incidence of local control (LC), distant recurrence (DC), disease-free survival (DFS) and overall survival (OS). We observed significant inverse correlations between RITA expression and tumour grading, the levels of HPV-16 virus DNA load, CD8 (+) tumour infiltrating lymphocytes and programmed death protein (PD-1) immunostaining. In univariate analyses, elevated levels of RITA expression were predictive for decreased local control (p = 0.001), decreased distant control (p = 0.040), decreased disease free survival (p = 0.001) and overall survival (p RITA expression remained significant for decreased local control (p = 0.009), disease free survival (p = 0.032) and overall survival (p = 0.012). These data indicate that elevated levels of pretreatment RITA expression are correlated with unfavourable clinical outcome in anal carcinoma treated with concomitant chemoradiotherapy. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. [RITA combined with temozolomide inhibits the proliferation of human glioblastoma U87 cells].

    Science.gov (United States)

    He, Xiao-Yan; Feng, Xiao-Li; Song, Xin-Pei; Zeng, Huan-Chao; Cao, Zhong-Xu; Xiao, Wei-Wei; Zhang, Bao; Wu, Qing-Hua

    2016-10-20

    To observe the effect of RITA, a small molecule that targets p53, combined with temozolomide (TMZ) on proliferation, colony formation and apoptosis of human glioblastoma U87 cells and explore the underlying mechanism. Cultured U87 cells were treated with RITA (1, 5, 10, 20 µmol/L), TMZ, or RITA+TMZ (half dose) for 24, 48 or 72 h. MTS assay were used to detect the cell proliferation, and the cell proliferation rate and inhibitory rate were calculated. The effect of combined treatments was evaluated by the q value. The expressions of p53, p21 and other apoptosis-associated genes were detected by qRT-PCR and Western blotting; cell apoptosis was assayed using flow cytometry with Annexin V/PI double staining; colony formation of the cells was detected with crystal violet staining. MTS assay showed that RITA at the 4 doses more potently inhibited U87 cell viability than TMZ at 72 h (P=0.000) with inhibitory rates of 25.94%-41.38% and 3.84%-8.20%, respectively. RITA combined with TMZ caused a more significant inhibition of U87 cells (29.21%-52.11%) than RITA (PRITA+TMZ for 48 h resulted in q values exceeding 1.2 and showed an obvious synergistic effect of the drugs. Both RITA and TMZ, especially the latter, significantly increased the expressions of p53, p21, puma, and other apoptosis-associated genes to accelerate apoptosis and inhibit the growth and colony formation of U87 cells, and the effect was more obvious with a combined treatment. RITA inhibits the growth of human glioblastoma cells and enhance their sensitivity to TMZ by up-regulating p53 expression, and when combined, RITA and TMZ show a synergistic effect to cause a stronger cell inhibition.

  18. A Green Prison: The Santa Rita Jail Campus Microgrid

    Energy Technology Data Exchange (ETDEWEB)

    Marnay, Chris; DeForest, Nicholas; Lai, Judy

    2012-01-22

    A large microgrid project is nearing completion at Alameda County’s twenty-two-year-old 45 ha 4,000-inmate Santa Rita Jail, about 70 km east of San Francisco. Often described as a green prison, it has a considerable installed base of distributed energy resources (DER) including an eight-year old 1.2 MW PV array, a five-year old 1 MW fuel cell with heat recovery, and considerable efficiency investments. A current US$14 M expansion adds a 2 MW-4 MWh Li-ion battery, a static disconnect switch, and various controls upgrades. During grid blackouts, or when conditions favor it, the Jail can now disconnect from the grid and operate as an island, using the on-site resources described together with its back-up diesel generators. In other words, the Santa Rita Jail is a true microgrid, or μgrid, because it fills both requirements, i.e. it is a locally controlled system, and it can operate both grid connected and islanded. The battery’s electronics includes Consortium for Electric Reliability Technology (CERTS) Microgrid technology. This enables the battery to maintain energy balance using droops without need for a fast control system.

  19. Integration& Operation of a Microgrid at Santa Rita Jail

    Energy Technology Data Exchange (ETDEWEB)

    Chevron Energy Solutions; Alameda County; DeForest, Nicholas; Lai, Judy; Stadler, Michael; Mendes, Goncalo; Marnay, Chris; Donadee, Jon

    2011-05-01

    Santa Rita Jail is a 4,500 inmate facility located in Dublin CA, approximately 40 miles (65 km) east of San Francisco. Over the past decade, a series of Distributed Energy Resources (DER) installations and efficiency measures have been undertaken to transform the 3MW facility into a"Green Jail". These include a 1.2MW rated rooftop PV system installed in 2002, a 1MW molten carbonate fuel cell with CHP, and retrofits to lighting and HVAC systems to reduce peak loads. With the upcoming installation of a large-scale battery and fast static disconnect switch, Santa Rita Jail will become a true microgrid, with full CERTS Microgrid functionality. Consequently, the jail will be able to seamlessly disconnect from the grid and operate as an island in the event of a disturbance, reconnecting again once the disturbance has dissipated. The extent to which that jail is capable of islanding is principally dependant on the energy capacity of the battery-one focus of this investigation. Also presented here are overviews of the DER currently installed at the jail, as well as the value it provides by offsetting the purchase of electricity under the current Pacific Gas& Electric (PG&E) tariff.

  20. Land Area Change and Fractional Water Maps in the Chenier Plain, Louisiana, following Hurricane Rita (2005)

    Science.gov (United States)

    Palaseanu-Lovejoy, Monica; Kranenburg, Christine J.; Brock, John C.

    2010-01-01

    In this study, we estimated the changes in land and water coverage of a 1,961-square-kilometer (km2) area in Louisiana's Chenier Plain. The study area is roughly centered on the Sabine National Wildlife Refuge, which was impacted by Hurricane Rita on September 24, 2005. The objective of this study is twofold: (1) to provide pre- and post-Hurricane Rita moderate-resolution (30-meter (m)) fractional water maps based upon multiple source images, and (2) to quantify land and water coverage changes due to Hurricane Rita.

  1. Positional stabilization of communications satellites - The RITA ion propulsion system is ready for commercial use

    Science.gov (United States)

    The radiofrequency ion thruster assembly (RITA) intended for service aboard the new Artemis communications satellite will operate for three hours twice a day, in order to furnish orbital position adjustments that keep antennas accurately pointed toward the earth. These engines are, despite such frequent and sustained use, projected to eject no more than 30 kG of Xe over the course of a decade. RITA operation is also extremely reliable and, due to its very low propellant consumption, is the basis of a long satellite service life. RITA will be among the 15 experiments that are to be performed by ESA's Eureca research satellite.

  2. Stewart-Treves Syndrome on the Lower Extremity Associated to Idiopathic Chronic Lymphedema Visualized on FDG PET/CT

    DEFF Research Database (Denmark)

    Brittain, Jane Maestri; Nymark, Tine; Hildebrandt, Malene Grubbe

    2017-01-01

    Angiosarcomas are highly malignant and rare tumors of vascular or lymphatic endothelial cell origin with a poor prognosis. Lymphangiosarcoma associated with chronic lymphedema is known as Stewart-Treves syndrome. Stewart-Treves syndrome is primarily described in patients with lymphedema of an upper...... extremity occurring after breast cancer surgery including radical axillary lymph node dissection and subsequent radiotherapy. It is rarely described in the presence of idiopathic chronic lymphedema of the lower extremities. We present a case of lymphangiosarcoma visualized on F-FDG PET/CT, where Stewart...

  3. Has Stewart approach improved our ability to diagnose acid-base disorders in critically ill patients?

    Science.gov (United States)

    Masevicius, Fabio D; Dubin, Arnaldo

    2015-02-04

    The Stewart approach-the application of basic physical-chemical principles of aqueous solutions to blood-is an appealing method for analyzing acid-base disorders. These principles mainly dictate that pH is determined by three independent variables, which change primarily and independently of one other. In blood plasma in vivo these variables are: (1) the PCO2; (2) the strong ion difference (SID)-the difference between the sums of all the strong (i.e., fully dissociated, chemically nonreacting) cations and all the strong anions; and (3) the nonvolatile weak acids (Atot). Accordingly, the pH and the bicarbonate levels (dependent variables) are only altered when one or more of the independent variables change. Moreover, the source of H(+) is the dissociation of water to maintain electroneutrality when the independent variables are modified. The basic principles of the Stewart approach in blood, however, have been challenged in different ways. First, the presumed independent variables are actually interdependent as occurs in situations such as: (1) the Hamburger effect (a chloride shift when CO2 is added to venous blood from the tissues); (2) the loss of Donnan equilibrium (a chloride shift from the interstitium to the intravascular compartment to balance the decrease of Atot secondary to capillary leak; and (3) the compensatory response to a primary disturbance in either independent variable. Second, the concept of water dissociation in response to changes in SID is controversial and lacks experimental evidence. In addition, the Stewart approach is not better than the conventional method for understanding acid-base disorders such as hyperchloremic metabolic acidosis secondary to a chloride-rich-fluid load. Finally, several attempts were performed to demonstrate the clinical superiority of the Stewart approach. These studies, however, have severe methodological drawbacks. In contrast, the largest study on this issue indicated the interchangeability of the Stewart and

  4. Early Cretaceous dextral transpressional deformation within the Median Batholith, Stewart Island, New Zealand

    International Nuclear Information System (INIS)

    Allibone, A.H.; Tulloch, A.J.

    2008-01-01

    The character, timing, and significance of deformation within the Median Batholith has been debated since at least 1967, with allochthonous and autochthonous models proposed to account for internal variations in the character of the batholith. Stewart Island provides excellent exposures of intrabatholithic structures, allowing many aspects of the deformation history within the batholith to be analysed, far removed from the effects of later deformation related to the current plate boundary. Median Batholith rocks in northern and central Stewart Island are deformed by three major structures: the Freshwater Fault System, Escarpment Fault, and Gutter Shear Zone. Lineation orientations, Al in hornblende geobarometry, and Ar-Ar thermochronology indicate up to c. 7 km of NNE-directed uplift of the hanging wall of the Escarpment Fault between c. 110 and 105 Ma. Unlike the Escarpment Fault, a wide range of mineral elongation lineation orientations, including many oblique to the strike and dip of related foliations, characterise both the Gutter Shear Zone and Freshwater Fault System. Lineation and limited sense of shear data indicate dextral-reverse movement on both structures during development of their dominant ductile fabrics. Crosscutting and intrusive relationships indicate movement on the Freshwater Fault System after c. 130 Ma and on the Gutter Shear Zone between 120 and 112 Ma. The amount of movement on the Freshwater Fault System and Gutter Shear Zone remains largely unconstrained. However, the 342 ± 24 Ma age of a granite clast in a Paterson Group lithic tuff horizon at Abrahams Bay overlaps that of Carboniferous plutons in the block immediately south of the Freshwater Fault System, implying that the Paterson Group is little displaced from the basement rocks through which it was erupted. The three structures mapped on Stewart Island form part of a narrow transpressional mobile belt active within the Jurassic-Cretaceous arc on the outboard margin of the Western

  5. Obituary: Anne Barbara Underhill, 1920-2003

    Science.gov (United States)

    Roman, Nancy Grace

    2003-12-01

    Anne was born in Vancouver, British Columbia on 12 June 1920. Her parents were Frederic Clare Underhill, a civil engineer and Irene Anna (née Creery) Underhill. She had a twin brother and three younger brothers. As a young girl she was active in Girl Guides and graduated from high school winning the Lieutenant Governor's medal as one of the top students in the Province. She also excelled in high school sports. Her mother died when Anne was 18 and, while undertaking her university studies, Anne assisted in raising her younger brothers. Her twin brother was killed in Italy during World War II (1944), a loss that Anne felt deeply. Possibly because of fighting to get ahead in astronomy, a field overwhelming male when she started, she frequently appeared combative. At the University of British Columbia, Anne obtained a BA (honors) in Chemistry (1942), followed by a MA in 1944. After working for the NRC in Montreal for a year, she studied at the University of Toronto prior to entering the University of Chicago in 1946 to obtain her PhD. Her thesis was the first model computed for a multi-layered stellar atmosphere (1948). During this time she worked with Otto Struve, developing a lifetime interest in hot stars and the analysis of their high dispersion spectra. She received two fellowships from the University Women of Canada. She received a U.S. National Research Fellowship to work at the Copenhagen Observatory, and upon its completion, she returned to British Columbia to work at the Dominion Astrophysical Observatory as a research scientist from 1949--1962. During this period she spent a year at Harvard University as a visiting professor and at Princeton where she used their advanced computer to write the first code for modeling stellar atmospheres. Anne was invited to the University of Utrecht (Netherlands) as a full professor in 1962. She was an excellent teacher, well liked by the students in her classes, and by the many individuals that she guided throughout her

  6. Ann Arbor Session I: Breaking Ground.

    Science.gov (United States)

    Music Educators Journal, 1979

    1979-01-01

    Summarizes the first session of the National Symposium on the Applications of Psychology to the Teaching and Learning of Music held at Ann Arbor from October 30 to November 2, 1978. Sessions concerned auditory perception, motor learning, child development, memory and information processing, and affect and motivation. (SJL)

  7. Ilmus artiklikogumik "Eesti teadlased paguluses" / Anne Valmas

    Index Scriptorium Estoniae

    Valmas, Anne, 1941-2017

    2009-01-01

    TLÜ AR väliseesti kirjanduse keskuse ja TTÜ Raamatukogu koostöös 24.03.2009 toimunud konverentsist "Eesti teadlased paguluses", mis tutvustas väliseesti teadlaste osa maailmateaduses. Ettekannete põhjal valminud artiklikogumikust "Eesti teadlased paguluses", koostajad Vahur Mägi ja Anne Valmas. Tallinn : Tallinna Ülikooli Kirjastus, 2009

  8. Reflection on Lessons Learned: An Analysis of the Adverse Outcomes Observed During the Hurricane Rita Evacuation.

    Science.gov (United States)

    Baker, Karen

    2018-02-01

    In September 2005, nearly 3.7 million people evacuated the Texas coastline in advance of Hurricane Rita's landfall, making the event the largest emergency evacuation in US history. The Rita evacuation underscored the importance of planning for domestic mass-evacuation events, as the evacuation itself led to over 100 of the at least 119 deaths attributed to the storm. In the days preceding Rita's landfall, several cascading, interrelated circumstances precipitated such adverse outcomes. This article explores the series of events leading up to the evacuation's poor outcomes, the response following Rita to amend evacuation plans, and how Texas successfully implemented these changes during later storms to achieve better outcomes. (Disaster Med Public Health Preparedness. 2018;12:115-120).

  9. (18)F-FDG PET/CT in a rare case of Stewart-Treves syndrome

    DEFF Research Database (Denmark)

    Jensen, Mads Radmer; Friberg, Lars; Karlsmark, Tonny

    2011-01-01

    high (18)F-FDG uptake in STS, but is at the same time an example of the low specificity of this imaging modality. CONCLUSIONS: We suggest that (18)F-FDG PET/CT has the potential to become an important tool in the staging and treatment planning of Stewart-Treves syndrome. Furthermore, (18)F...... of Stewart-Treves Syndrome (STS), angiosarcoma secondary to chronic extremity lymphedema, are presented. Lymphedema of the extremities is a debilitating disease characterized by chronic swelling due to interstitial edema caused by insufficient lymphatic drainage capacity. Progression with skin thickening......-FDG-accumulation may be a sensitive tool in detecting low grade inflammation in the skin and subcutis, which has been suggested to cause tissue remodeling in lymphedema progression. However, further studies are needed to elucidate this theory....

  10. [Metabolic alkalosis despite hyperlactatemia and hypercapnia. Interpretation and therapy with help of the Stewart concept].

    Science.gov (United States)

    Chappell, D; Hofmann-Kiefer, K; Jacob, M; Conzen, P; Rehm, M

    2008-02-01

    Acid-base disturbances are commonly found in critically ill patients and are often associated with fatal complications. The basis of a successful treatment is a thorough understanding of the causes of these disorders. The "classical methods" to explain acid-base disorders--pH, base excess and bicarbonate concentration--mostly do not provide a causal correlation to the underlying pathology. An unusual case of a combined respiratory-metabolic disorder with hyperlactatemia and hypercapnia is presented. An acidosis masked by hypochloremic and hypoalbuminemic alkalosis was identified with the help of Stewart's concept and finally permitted a successful therapy. The modern Stewart concept provides enhanced information, enabling an exact diagnosis and causal therapy even in complex cases.

  11. Natural gas cost for evaluating energy resource opportunities at Fort Stewart

    Energy Technology Data Exchange (ETDEWEB)

    Stucky, D.J.; Shankle, S.A.

    1993-01-01

    Ft. Stewart, a United States Army Forces Command (FORSCOM) installation located near Hinesville, Georgia, is currently undergoing an evaluation of its energy usage, which is being performed by Pacific Northwest Laboratory. In order to examine the energy resource opportunities (EROs) at Ft. Stewart, marginal fuel costs must be calculated. The marginal, or avoided, cost of gas service is used in conjunction with the estimated energy savings of an ERO to calculate the dollar value of those savings. In the case of natural gas, the costing becomes more complicated due to the installation of a propane-air mixing station. The propane-air station is being built under a shared energy savings (SES) contract. The building of a propane-air station allows Ft. Stewart to purchase natural gas from their local utility at an interruptible rate, which is lower than the rate for contracting natural gas on a firm basis. The propane-air station will also provide Ft. Stewart with fuel in the event that the natural gas supply is curtailed. While the propane-air station does not affect the actual cost of natural gas, it does affect the cost of services provided by gas. Because the propane-air station and the SES contract affect the cost of gas service, they must be included in the analysis. Our analysis indicates a marginal cost of gas service of 30.0 cents per therm, assuming a total propane usage by the mixing station of 42,278 gallons (38,600 therms) annually. Because the amount of propane that may be required in the event of a curtailment is small relative to the total service requirement, variations in the actual amount should not significantly affect the cost per therm.

  12. Natural gas cost for evaluating energy resource opportunities at Fort Stewart

    International Nuclear Information System (INIS)

    Stucky, D.J.; Shankle, S.A.

    1993-01-01

    Ft. Stewart, a United States Army Forces Command (FORSCOM) installation located near Hinesville, Georgia, is currently undergoing an evaluation of its energy usage, which is being performed by Pacific Northwest Laboratory. In order to examine the energy resource opportunities (EROs) at Ft. Stewart, marginal fuel costs must be calculated. The marginal, or avoided, cost of gas service is used in conjunction with the estimated energy savings of an ERO to calculate the dollar value of those savings. In the case of natural gas, the costing becomes more complicated due to the installation of a propane-air mixing station. The propane-air station is being built under a shared energy savings (SES) contract. The building of a propane-air station allows Ft. Stewart to purchase natural gas from their local utility at an interruptible rate, which is lower than the rate for contracting natural gas on a firm basis. The propane-air station will also provide Ft. Stewart with fuel in the event that the natural gas supply is curtailed. While the propane-air station does not affect the actual cost of natural gas, it does affect the cost of services provided by gas. Because the propane-air station and the SES contract affect the cost of gas service, they must be included in the analysis. Our analysis indicates a marginal cost of gas service of 30.0 cents per therm, assuming a total propane usage by the mixing station of 42,278 gallons (38,600 therms) annually. Because the amount of propane that may be required in the event of a curtailment is small relative to the total service requirement, variations in the actual amount should not significantly affect the cost per therm

  13. Richard Doll and Alice Stewart: reputation and the shaping of scientific "truth".

    Science.gov (United States)

    Greene, Gayle

    2011-01-01

    As the world watched the Fukushima reactors release radionuclides into the ocean and atmosphere, the warnings of Dr. Alice Stewart about radiation risk and the reassurances of Sir Richard Doll assumed renewed relevance. Doll and Stewart, pioneer cancer epidemiologists who made major contributions in the 1950s-he by demonstrating the link between lung cancer and smoking, she by discovering that fetal X-rays double the chance of a childhood cancer-were locked into opposition about low-dose radiation risk. When she went public with the discovery that radiation at a fraction of the dose "known" to be dangerous could kill a child, her reputation plummeted, whereas Doll, foremost among her detractors, was knighted and lauded as "the world's most distinguished medical epidemiologist" for his work. Their lives and careers, so closely intertwined, took contrary courses, he becoming "more of the establishment" (as he said), while she became more oppositional. When it was discovered, after his death, that he'd been taking large sums of money from industries whose chemicals he was clearing of cancer risk, his reputation remained unscathed; it is now enshrined in the "Authorized Biography" (2009) commissioned by the Wellcome Institute, along with Doll's denigration of Stewart as an "embittered" woman and biased scientist. Stewart lived long enough to see radiation science move her way, to see international committees affirm, in the 1990s, that there is no threshold beneath which radiation ceases to be dangerous; recent evidence from Chernobyl is bearing out her warnings. But a look at the making and breaking of these reputations reveals the power of status, position, and image to shape scientific "knowledge" and social policy.

  14. Mold exposure and health effects following hurricanes Katrina and Rita.

    Science.gov (United States)

    Barbeau, Deborah N; Grimsley, L Faye; White, LuAnn E; El-Dahr, Jane M; Lichtveld, Maureen

    2010-01-01

    The extensive flooding in the aftermath of Hurricanes Katrina and Rita created conditions ideal for indoor mold growth, raising concerns about the possible adverse health effects associated with indoor mold exposure. Studies evaluating the levels of indoor and outdoor molds in the months following the hurricanes found high levels of mold growth. Homes with greater flood damage, especially those with >3 feet of indoor flooding, demonstrated higher levels of mold growth compared with homes with little or no flooding. Water intrusion due to roof damage was also associated with mold growth. However, no increase in the occurrence of adverse health outcomes has been observed in published reports to date. This article considers reasons why studies of mold exposure after the hurricane do not show a greater health impact.

  15. Transformative experiences for Hurricanes Katrina and Rita disaster volunteers.

    Science.gov (United States)

    Clukey, Lory

    2010-07-01

    The massive destruction caused by Hurricanes Katrina and Rita in 2005 provided an opportunity for many volunteers to be involved with disaster relief work. Exposure to devastation and personal trauma can have long-lasting and sometimes detrimental effects on people providing help. This qualitative study explored the experience of volunteer relief workers who provided disaster relief services after the hurricanes. Three major themes emerged: emotional reactions that included feelings of shock, fatigue, anger and grief as well as sleep disturbances; frustration with leadership; and life-changing personal transformation. Stress reactions were noted but appeared to be mitigated by feelings of compassion for the victims and personal satisfaction in being able to provide assistance. Suggestions are provided for further research.

  16. Stratigraphy of the Charqueadas Carboniferous basin, Santa Rita, RS, Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Mendes Piccoli, A.E.; Holz, M.; Munaro, P.

    1985-01-01

    Sedimentological analyses of about 80 drill cores from the Charqueadas - Santa Rita Coal Field, west of Porto Alegre, Rio Grande do Sul State, were made. The Itarare Group is characterized by pelites of lacustrine origin and conglomerates and sandstones of alluvial fans, mainly in the north western region. A shallow lacustrine and paludal system characterize the Rio Bonito Formation, comprising coal seams and associated pelitic sediments, as well as some paraconglomerates and sandstone layers. The contact between these units is established by the colour of the pelites, differences in sedimentary textures, structures and palynological data. A marine transgression caused the sediments of the Rio Bonito Formation to be covered by coastal sandstones and pelites of the Palermo Formation, of tidal flat origin. Today, the coal layers and sediments have been eroded southward and slope gently to the north of the area.

  17. Katrina and Rita were lit up with lightning

    Science.gov (United States)

    Shao, X.-M.; Harlin, J.; Stock, M.; Stanley, M.; Regan, A.; Wiens, K.; Hamlin, T.; Pongratz, M.; Suszcynsky, D.; Light, T.

    Hurricanes generally produce very little lightning activity compared to other noncyclonic storms, and lightning is especially sparse in the eye wall and inner regions within tens of kilometers surrounding the eye [Molinari et al., 1994, 1999]. (The eye wall is the wall of clouds that encircles the eye of the hurricane.) Lightning can sometimes be detected in the outer, spiral rainbands, but the lightning occurrence rate varies significantly from hurricane to hurricane as well as within an individual hurricane's lifetime.Hurricanes Katrina and Rita hit the U.S. Gulf coasts of Louisiana, Mississippi, and Texas, and their distinctions were not just limited to their tremendous intensity and damage caused. They also differed from typical hurricanes in their lightning production rate.

  18. RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J.

    Science.gov (United States)

    Wacker, Stephan Armin; Alvarado, Cristobal; von Wichert, Götz; Knippschild, Uwe; Wiedenmann, Jörg; Clauss, Karen; Nienhaus, Gerd Ulrich; Hameister, Horst; Baumann, Bernd; Borggrefe, Tilman; Knöchel, Walter; Oswald, Franz

    2011-01-05

    The evolutionarily conserved Notch signal transduction pathway regulates fundamental cellular processes during embryonic development and in the adult. Ligand binding induces presenilin-dependent cleavage of the receptor and a subsequent nuclear translocation of the Notch intracellular domain (NICD). In the nucleus, NICD binds to the recombination signal sequence-binding protein J (RBP-J)/CBF-1 transcription factor to induce expression of Notch target genes. Here, we report the identification and functional characterization of RBP-J interacting and tubulin associated (RITA) (C12ORF52) as a novel RBP-J/CBF-1-interacting protein. RITA is a highly conserved 36 kDa protein that, most interestingly, binds to tubulin in the cytoplasm and shuttles rapidly between cytoplasm and nucleus. This shuttling RITA exports RBP-J/CBF-1 from the nucleus. Functionally, we show that RITA can reverse a Notch-induced loss of primary neurogenesis in Xenopus laevis. Furthermore, RITA is able to downregulate Notch-mediated transcription. Thus, we propose that RITA acts as a negative modulator of the Notch signalling pathway, controlling the level of nuclear RBP-J/CBF-1, where its amounts are limiting.

  19. IGF-1R/MDM2 relationship confers enhanced sensitivity to RITA in Ewing sarcoma cells.

    Science.gov (United States)

    Di Conza, Giusy; Buttarelli, Marianna; Monti, Olimpia; Pellegrino, Marsha; Mancini, Francesca; Pontecorvi, Alfredo; Scotlandi, Katia; Moretti, Fabiola

    2012-06-01

    Ewing sarcoma is one of the most frequent bone cancers in adolescence. Although multidisciplinary therapy has improved the survival rate for localized tumors, a critical step is the development of new drugs to improve the long-term outcome of recurrent and metastatic disease and to reduce side effects of conventional therapy. Here, we show that the small molecule reactivation of p53 and induction of tumor cell apoptosis (RITA, NSC652287) is highly effective in reducing growth and tumorigenic potential of Ewing sarcoma cell lines. These effects occur both in the presence of wt-p53 as well as of mutant or truncated forms of p53, or in its absence, suggesting the presence of additional targets in this tumor histotype. Further experiments provided evidence that RITA modulates an important oncogenic mark of these cell lines, insulin-like growth factor receptor 1 (IGF-1R). Particularly, RITA causes downregulation of IGF-1R protein levels. MDM2 degradative activity is involved in this phenomenon. Indeed, inhibition of MDM2 function by genetic or pharmacologic approaches reduces RITA sensitivity of Ewing sarcoma cell lines. Overall, these data suggest that in the cell context of Ewing sarcoma, RITA may adopt additional mechanism of action besides targeting p53, expanding its field of application. Noteworthy, these results envisage the promising utilization of RITA or its derivative as a potential treatment for Ewing sarcomas. ©2012 AACR

  20. Rescue of the apoptotic-inducing function of mutant p53 by small molecule RITA.

    Science.gov (United States)

    Zhao, Carolyn Y; Grinkevich, Vera V; Nikulenkov, Fedor; Bao, Wenjie; Selivanova, Galina

    2010-05-01

    Expression of mutant p53 correlates with poor prognosis in many tumors, therefore strategies aimed at reactivation of mutant p53 are likely to provide important benefits for treatment of tumors that are resistant to chemotherapy and radiotherapy. We have previously identified and characterized a small molecule RITA which binds p53 and induces a conformational change which prevents the binding of p53 to several inhibitors, including its own destructor MDM2. In this way, RITA rescues the tumor suppression function of wild type p53. Here, we demonstrate that RITA suppressed the growth and induced apoptosis in human tumor cell lines of a diverse origin carrying mutant p53 proteins. RITA restored transcriptional transactivation and transrepression function of several hot spot p53 mutants. The ability of RITA to rescue the activity of different p53 mutants suggests its generic mechanism of action. Thus, RITA is a promising lead for the development of anti-cancer drugs that reactivate the tumor suppressor function of p53 in cancer cells irrespective whether they express mutant or wild type p53.

  1. Anne-Mette Langes plan for ADHD kongressen

    DEFF Research Database (Denmark)

    Lange, Anne-Mette

    2017-01-01

    http://medicinsktidsskrift.dk/behandlinger/psykiatri/699-anne-mette-langes-plan-for-adhd-kongressen.html......http://medicinsktidsskrift.dk/behandlinger/psykiatri/699-anne-mette-langes-plan-for-adhd-kongressen.html...

  2. Neuropsychological profile of a male psychiatric patient with a Morgagni-Stewart-Morel syndrome.

    Science.gov (United States)

    Hansen, Aksel; Engelhardt, Liliana; Pleschutznig, Wolfgang; Dammann, Gerhard; Vietze, Stephanie

    2015-02-01

    In 1765 Giovanni Morgagni described a syndrome consisting of hyperostosis frontalis interna (HFI), obesity and hirsutism. In 1928 Stewart and in 1930 Morel added neuropsychiatric symptoms, e.g. depression and dementia, which led to the definition of the Morgagni-Stewart-Morel Syndrome (MSM). Although mostly women were characterized in literature no gender specifity is demanded. This case report presents the rare case of a 66 year old male psychiatric patient with Morgagni-Stewart-Morel Syndrome. The patient complained of loss of concentration and difficulties with activities of daily living. Admission diagnosis was an opioid misuse on the basis of a chronic pain syndrome. In this case report we are describing clinical features, the patient history and technical (MRI) and neuropsychological tests. Although severe psychiatric symptoms and neuropsychological deficits are commonly seen in these patients, our patient showed only mild symptoms. This case reports shows the possibility of a male patient with MSM. If MSM is a separate entity or just an epiphenomena of hormone dysregulation should be investigated in further studies.

  3. A new perspective on autism: Rita Leal School

    Directory of Open Access Journals (Sweden)

    Rodrigues T. F.

    2016-12-01

    Full Text Available Guided by the principle that scientific knowledge should serve to transform reality and create suitable conditions of life for all, the Portuguese Association for Relational-Historical Psychology (APPRH founded a school named RITA LEAL (RLS, with a therapeutic purpose based on new perspectives for treating autism — perspectives quite different from instrumental and behavioral learning programs. The Rita Leal School (Leal, 1975/2004, 1997, 2005, 2010 is rooted in the theory that mental development is based on a mutually contingent emotional relationship, while it underwrites Vygotsky’s concept of the Zone of Proximal Development (ZPD and Mediation (1930/2004, 1934/2009. Learning to read is a complex process which individuals with Autism Spectrum Disorder (ASD master slowly and with difficulty. We analyzed the process of learning to read of two ASD children accompanied by peers without special educational needs, aiming to pinpoint distinct aspects of their progress. We used the Observer Software Program to collect and analyze observations of their performance, which were understood as data to be classified according to previously specified codes. We believed we could demonstrate that, especially in the case of ASD children, learning is dependent on contingent responses and adequate levels of mediation. The technical team at the RLS has continuous clinical supervision. That is because we believe this supervision is what permits the team to undergo a process of de-centering, becoming more empathic and accessible to the autists. This makes the team’s intervention more efficient, because it becomes more aware of each autist’s individual characteristics, and therefore more available to respond to the autist’s needs.

  4. Impact of hurricanes katrina and rita on the anesthesiology workforce.

    Science.gov (United States)

    Hutson, Larry R; Vega, Jorge; Schubert, Armin

    2011-01-01

    Hurricanes Katrina and Rita impacted a large portion of the medical community in Louisiana. We attempt to determine their impact on the anesthesiology workforce in Louisiana. In May 2006, a survey was mailed to 368 Louisiana anesthesiologists, collecting demographic data, retirement plans, impact of Hurricanes Katrina and Rita, position vacancies, practice conditions, and the general state of healthcare in their area. All 3 anesthesiology residency programs in the state were contacted regarding their recent graduates. The 2010 RAND survey of the anesthesiology workforce was reviewed with respect to findings relevant to the state and region. One hundred seventy surveys were returned, yielding a 46.2% response rate. Among the respondents, 13.9% intended to retire within 5 years and another 24% in 5 to 10 years. Since 2005, 63.9% had seen an increase in their daily caseload, 46.9% saw an increase in work hours, and 36.8% stated that their practices were trying to hire new anesthesiologists and were having difficulty filling these positions. Since 2005, the number of anesthesiology residents in Louisiana had declined by almost 50%, and the number of graduates remaining to practice in Louisiana had decreased by 43% from 7 to 4 annually. Our 2006 survey provided qualitative evidence for a shortage of anesthesiologists in the state of Louisiana after the natural disasters in 2005 that was likely to worsen as residency output plummeted, fewer residents stayed in the state, and projected retirement increased. The regional data from the RAND survey a year later confirmed the impressions from our survey, with an estimate of an anesthesiologist shortage as high as 39% of the workforce. State membership surveys may serve as accurate barometers in the wake of major environmental upheavals affecting regional anesthesiology workforce conditions.

  5. Singularity kinematics principle and position-singularity analyses of the 6-3 Stewart-Gough parallel manipulators

    International Nuclear Information System (INIS)

    Cao, Yi; Zhou, Hui; Li, Baokun; Shen, Long

    2011-01-01

    This paper presents a new principle and method of kinematics to analyze the singularity of Stewart-Gough parallel manipulators and addresses the property identification of the position-singularity loci of the 6-3 Stewart-Gough manipulators for special orientations. Based on the kinematic relationship of a rigid body, a necessary and sufficient condition that three velocities of three non-collinear points in a moving rigid body can determine a screw motion is addressed and some typical singular configurations of the 6-3 Stewart-Gough parallel manipulators are also addressed in detail. With the above-mentioned condition, a symbolic analytical polynomial expression of degree three in the moving platform position parameters, representing the position-singularity locus of the 6-3 Stewart-Gough manipulators for special orientations, is derived: and the property identification of the position-singularity loci of the 6-3 Stewart-Gough manipulator for these special orientations is investigated at length. It is shown that position-singularity loci of the 6-3 Stewart-Gough parallel manipulator for these special orientations will be a plane and a hyperbolic paraboloid, even three intersecting planes

  6. RITA plus 3-MA overcomes chemoresistance of head and neck cancer cells via dual inhibition of autophagy and antioxidant systems.

    Science.gov (United States)

    Shin, Daiha; Kim, Eun Hye; Lee, Jaewang; Roh, Jong-Lyel

    2017-10-01

    Reactivation of p53 and induction of tumor cell apoptosis (RITA) is a small molecule that blocks p53-MDM2 interaction, thereby reactivating p53 in tumors. RITA can induce exclusive apoptosis in cancer cells independently of the p53 pathway; however, the resistance of cancer cells remains a major drawback. Here, we found a novel resistance mechanism of RITA treatment and an effective combined treatment to overcome RITA resistance in head and neck cancer (HNC) cells. The effects of RITA and 3-methyladenine (3-MA) were tested in different HNC cell lines, including cisplatin-resistant and acquired RITA-resistant HNC cells. The effects of each drug alone and in combination were assessed by measuring cell viability, apoptosis, cell cycle, glutathione, reactive oxygen species, protein expression, genetic inhibition of p62 and Nrf2, and a mouse xenograft model of cisplatin-resistant HNC. RITA induced apoptosis of HNC cells at different levels without significantly inhibiting normal cell viability. Following RITA treatment, RITA-resistant HNC cells exhibited a sustained expression of other autophagy-related proteins, overexpressed p62, and displayed activation of the Keap1-Nrf2 antioxidant pathway. The autophagy inhibitor 3-MA sensitized resistant HNC cells to RITA treatment via the dual inhibition of molecules related to the autophagy and antioxidant systems. Silencing of the p62 gene augmented the combined effects. The effective antitumor activity of RITA plus 3-MA was also confirmed in vivo in mouse xenograft models transplanted with resistant HNC cells, showing increased oxidative stress and DNA damage. The results indicate that RITA plus 3-MA can help overcome RITA resistance in HNC cells. This study revealed a novel RITA resistant mechanism associated with the sustained induction of autophagy, p62 overexpression, and Keap1-Nrf2 antioxidant system activation. The combined treatment of RITA with the autophagy inhibitor 3-methyladenine overcomes RITA resistance via dual

  7. Ritacestus gen. n. (Cestoda: Proteocephalidea) and redescription of R. ritaii comb. n., a parasite of Rita rita (Siluriformes) in India.

    Science.gov (United States)

    de Chambrier, Alain; Scholz, Tomás; Ash, Anirban; Kar, Pradip Kumar

    2011-11-01

    A new genus, Ritacestus, is proposed to accommodate Ritacestus ritaii (Verma, 1926) comb. n. (syn. Proteocephalus ritaii), a parasite of the catfish Rita rita (Hamilton) in India. The new genus, which is placed in the Gangesiinae, is characterized by (i) a small, subspherical scolex formed by four large lobes separated from one another by longitudinal grooves, with a large, widely oval to pyriform rostellum-like apical organ, larger than suckers and possessing an apical hemispherical depression; (ii) paramuscular and cortical position of some vitelline follicles (most follicles are situated medullary); (iii) ventral and dorsal bands of vitelline follicles usually uninterrupted ventral to terminal genitalia and reaching to the posterior margin of proglottides; (iv) the vagina always anterior to the cirrus-sac; (v) a large size of the body (length up to 51 cm); and (vi) development of the uterus of type 2. In its morphology, especially shape of the scolex and apical organ, and paramuscular and cortical position of some vitelline follicles, Ritacestus resembles Postgangesia Akhmerov, 1969, but differs in the presence of a genital atrium (both genital pores of Postgangesia are separate), the anterior position of the vagina (almost always posterior in the latter genus), position of vitelline follicles in cross sections (dorsal and ventral bands in Ritacestus versus only a lateral band in the latter genus), and dorsal excretory canals indistinguishable in mature and gravid proglottides of R. ritaii (well developed in Postgangesia spp.). The type and only species of the genus, R. ritaii, is redescribed on the basis of new material from the type host from the Ganges River basin in India and its neotype is designated.

  8. 44 CFR 206.209 - Arbitration for Public Assistance determinations related to Hurricanes Katrina and Rita (Major...

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Arbitration for Public Assistance determinations related to Hurricanes Katrina and Rita (Major disaster declarations DR-1603, DR... determinations related to Hurricanes Katrina and Rita (Major disaster declarations DR-1603, DR-1604, DR-1605, DR...

  9. Recognizing history in range ecology: 100 years of science and management on the Santa Rita Experimental Range

    Science.gov (United States)

    Nathan F. Sayre

    2003-01-01

    At the centennial of the Santa Rita Experimental Range, historical analysis is called for on two levels. First, as a major site in the history of range ecology, the Santa Rita illuminates past successes and failures in science and management and the ways in which larger social, economic, and political factors have shaped scientific research. Second, with the turn away...

  10. Kui vana on kunstnik? / Anneli Porri

    Index Scriptorium Estoniae

    Porri, Anneli, 1980-

    2003-01-01

    Rahvusvahelise kunstihariduse konverentsi "InSea on Sea" raames Kunstiakadeemia galeriis Karin Laansoo kureeritud Tallinna Kunstikooli õpilaste tööde näitus "MÄRKmed", Draakoni galeriis Mari Sobolevi kureeritud Viljandi Maagümnaasiumi kunstistuudio näitus "Sisseastumiseksam maailma", rahvusraamatukogus Anneli Porri kureeritud näitus "Kokkuvõte" EKA tänavuste lõpetajate töödest ja näitus "Leitud tagahoovist", Kullo galeriis rahvusvaheline näitus "Dialoog erinevuste vahel"

  11. Cafe Grandis kõlab lautomuusika / Anneli Remme

    Index Scriptorium Estoniae

    Remme, Anneli, 1968-

    2008-01-01

    Corelli Musicu salongiõhtutel festivali "Fiesta de la Guitarra" raames esineb trio koosseisus Stewart McCoy (lautomängija), Robert Staak (lautomängija) ja Maria Staak (laulja), esinejatest. Esitatakse renessansiaja autorite lautoduette ja -laule. Kontsert 8. nov. Pärnu hotellis sarjas "Café Grandi muusikasalong"

  12. Experimental control of Stewart's theoretical model of large amplitude moving striations

    International Nuclear Information System (INIS)

    Berge, G. van den; Vanmarcke, M.

    1977-01-01

    The longitudinal variation of the electron concentration in large amplitude moving striations, computed theoretically by Stewart, has been tested experimentally. The measurements are carried out by means of a sampling probe technique in the glow discharge of neon (I = 105 mA, 2R = 5.6 cm, p 0 = 0.79 torr) and of argon (I = 75 mA, 2R = 5.7 cm, p 0 = 0.46 torr). It is found that the measured dependence of the concentration is not consistent with the theory. (Auth.)

  13. Monitoring Inland Storm Surge and Flooding from Hurricane Rita

    Science.gov (United States)

    McGee, Benton D.; Tollett, Roland W.; Mason, Jr., Robert R.

    2006-01-01

    Pressure transducers (sensors) and high-water marks were used to document the inland water levels related to storm surge generated by Hurricane Rita in southwestern Louisiana and southeastern Texas. On September 22-23, 2005, an experimental monitoring network of sensors was deployed at 33 sites over an area of about 4,000 square miles to record the timing, extent, and magnitude of inland hurricane storm surge and coastal flooding. Sensors were programmed to record date and time, temperature, and barometric or water pressure. Water pressure was corrected for changes in barometric pressure and salinity. Elevation surveys using global-positioning systems and differential levels were used to relate all storm-surge water-level data, reference marks, benchmarks, sensor measuring points, and high-water marks to the North American Vertical Datum of 1988 (NAVD 88). The resulting data indicated that storm-surge water levels over 14 feet above NAVD 88 occurred at three locations, and rates of water-level rise greater than 5 feet per hour occurred at three locations near the Louisiana coast.

  14. Entrevista a María Rita Otero

    Directory of Open Access Journals (Sweden)

    Olga Lucia Castiblanco Abril

    2016-09-01

    Full Text Available OC: Dra. María Rita, bienvenida a esta sección de la revista en donde siempre queremos que nuestros lectores conozcan personas de la vida académica en el campo de la investigación en Enseñeanza de las Ciencias. En primer lugar, nos gustaría que nos contara algo sobre su lugar actual como docente e invstigadora. MRO: Muchas gracias por la invitación. Quisiera contarles que hasta hace dos años fui profesora de secundaria durante 33 años. Actualmente soy profesora titular de la Universidad del Centro de la Provincia de Buenos Aires y soy investigadora principal del Consejo Nacional de Ciencia y tecnología de la República Argentina (Conicet. OC: ¿Cuál es su área de investigación? MRO: Estoy adscrita en el área de psicología y educación. Dentro de esta área trabajo en didáctica de las ciencias. Dirijo un equipo dentro de la universidad que se dedica a esto y a formar profesores de matemáticas, física e informática y también dirijo el doctorado.

  15. Anneli Randla kaitses doktorikraadi Cambridge'is / Anneli Randla ; interv. Reet Varblane

    Index Scriptorium Estoniae

    Randla, Anneli, 1970-

    1999-01-01

    5. mail kaitses Cambridge'is esimese eesti kunstiteadlasena doktorikraadi Anneli Randla. Töö teema: kerjusmungaordukloostrite arhitektuur Põhja-Euroopas. Juhendaja dr. Deborah Howard. Doktorikraadile esitatavatest nõudmistest, doktoritöö kaitsmisest, magistrikraadi kaitsnu õppimisvõimalustest Cambridge's.

  16. Status of the RITA - experiment on EURECA. [Radio Frequency Ion Thrustor Assembly

    Energy Technology Data Exchange (ETDEWEB)

    Bassner, H.; Berg, H.P.; Birner, W.; Bartoli, C.; Trippi, A.

    1987-01-01

    The radiofrequency ion thruster assembly (RITA) is currently built as a flight experiment which shall be flown on the European retrievable carrier (Eureca I). This test flight shall verify the operational use of this electric propulsion system in space by demonstration of operation, lifetime and reliability. For this purpose the RITA experiment has been adapted to meet the specific constraints imposed by the Eureca I spacecraft and by the Space Shuttle as the launcher; xenon gas will be used as the propellant and the experiment will be operated automatically by means of a dedicated on-board microcomputer system. According to the delay in launches by the Space Shuttle the launch date has been postponed from March 1988 to 1991/92. Therefore the total Eureca program has been extended, which also influenced the RITA time schedule.

  17. Super capacitor modeling with artificial neural network (ANN)

    Energy Technology Data Exchange (ETDEWEB)

    Marie-Francoise, J.N.; Gualous, H.; Berthon, A. [Universite de Franche-Comte, Lab. en Electronique, Electrotechnique et Systemes (L2ES), UTBM, INRETS (LRE T31) 90 - Belfort (France)

    2004-07-01

    This paper presents super-capacitors modeling using Artificial Neural Network (ANN). The principle consists on a black box nonlinear multiple inputs single output (MISO) model. The system inputs are temperature and current, the output is the super-capacitor voltage. The learning and the validation of the ANN model from experimental charge and discharge of super-capacitor establish the relationship between inputs and output. The learning and the validation of the ANN model use experimental results of 2700 F, 3700 F and a super-capacitor pack. Once the network is trained, the ANN model can predict the super-capacitor behaviour with temperature variations. The update parameters of the ANN model are performed thanks to Levenberg-Marquardt method in order to minimize the error between the output of the system and the predicted output. The obtained results with the ANN model of super-capacitor and experimental ones are in good agreement. (authors)

  18. Preliminary assessment report for National Guard Training Center, Georgia Army National Guard, Fort Stewart, Georgia

    International Nuclear Information System (INIS)

    1993-07-01

    This report presents the results of the preliminary assessment (PA) conducted by Argonne National Laboratory at the Georgia Army National Guard (GAARNG) facility near Hinesville, Georgia, known as the National Guard Training Center (NGTC). Preliminary assessments of federal facilities are being conducted to compile the information necessary for completing preremedial activities and to provide a priority basis for completing corrective actions (where necessary) in response to releases of hazardous substances. The principal objective of the PA is to characterize the site accurately and determine the need for further action by examining previous site activities, types and quantities of hazardous substances utilized, and potential pathways by which contamination could affect public health and the environment. The scope of this assessment is limited to the facilities and past activities contained within the NGTC. Preliminary assessment site score sheet information is also provided for the NGTC. However, this assessment report is intended to be read in conjunction with a previous IRP assessment of Fort Stewart completed in 1992 (USATHAMA 1992) and to provide comprehensive information on the NGTC area for incorporation with information contained in that previous assessment for the entirety of Fort Stewart

  19. Israel-Stewart Approach to Viscous Dissipative Extended Holographic Ricci Dark Energy Dominated Universe

    Directory of Open Access Journals (Sweden)

    Surajit Chattopadhyay

    2016-01-01

    Full Text Available This paper reports a study on the truncated Israel-Stewart formalism for bulk viscosity using the extended holographic Ricci dark energy (EHRDE. Under the consideration that the universe is dominated by EHRDE, the evolution equation for the bulk viscous pressure Π in the framework of the truncated Israel-Stewart theory has been taken as τΠ˙+Π=-3ξH, where τ is the relaxation time and ξ is the bulk viscosity coefficient. Considering effective pressure as a sum of thermodynamic pressure of EHRDE and bulk viscous pressure, it has been observed that under the influence of bulk viscosity the EoS parameter wDE is behaving like phantom, that is, wDE≤-1. It has been observed that the magnitude of the effective pressure peff=p+Π is decaying with time. We also investigated the case for a specific choice of scale factor; namely, a(t=(t-t0β/(1-α. For this choice we have observed that a transition from quintessence to phantom is possible for the equation of state parameter. However, the ΛCDM phase is not attainable by the state-finder trajectories for this choice. Finally it has been observed that in both of the cases the generalized second law of thermodynamics is valid for the viscous EHRDE dominated universe enveloped by the apparent horizon.

  20. Stewart-Treves syndrome – case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Marta Koper

    2014-09-01

    Full Text Available Introduction . Chronic lymphedema, mainly due to total mastectomy with axillary lymph nodes dissection for breast cancer, can induce development of rare and highly malignant cutaneous angiosarcoma. This condition is called Stewart-Treves syndrome (STS. There are only about 400 cases of STS reported in the literature. The long-term prognosis is poor; 5-year survival is up to 10%. Limb amputation appears to be the treatment of choice. Objective . To present a case of Stewart-Treves syndrome with a fatal outcome, which developed 12 years after mastectomy with lymphadenectomy. Case report . A 65-year-old woman was admitted to our department for confluent purpuric macules, hemorrhagic blisters, and violaceous-black nodules, involving the whole left arm and forearm, with chronic severe lymphedema of the extremity. She had a history of left-sided breast cancer 12 years previously, treated with mastectomy with excision of axillary lymph nodes; subsequently, the failure of lymph drainage and lymph stasis developed. Histopathological examination of the tumor was consistent with angiosarcoma. The patient was disqualified from a surgical procedure due to the late stage of malignancy and died approximately a month later. Conclusions . Given unsatisfactory treatment options, the prevention of long-lasting lymphedema is crucial to improve prognosis of patients with breast cancer.

  1. Kinematics of an in-parallel actuated manipulator based on the Stewart platform mechanism

    Science.gov (United States)

    Williams, Robert L., II

    1992-01-01

    This paper presents kinematic equations and solutions for an in-parallel actuated robotic mechanism based on Stewart's platform. These equations are required for inverse position and resolved rate (inverse velocity) platform control. NASA LaRC has a Vehicle Emulator System (VES) platform designed by MIT which is based on Stewart's platform. The inverse position solution is straight-forward and computationally inexpensive. Given the desired position and orientation of the moving platform with respect to the base, the lengths of the prismatic leg actuators are calculated. The forward position solution is more complicated and theoretically has 16 solutions. The position and orientation of the moving platform with respect to the base is calculated given the leg actuator lengths. Two methods are pursued in this paper to solve this problem. The resolved rate (inverse velocity) solution is derived. Given the desired Cartesian velocity of the end-effector, the required leg actuator rates are calculated. The Newton-Raphson Jacobian matrix resulting from the second forward position kinematics solution is a modified inverse Jacobian matrix. Examples and simulations are given for the VES.

  2. Stewart-Bluefarb acroangiodermatitis in a case of Parkes-Weber syndrome

    Directory of Open Access Journals (Sweden)

    Deepti H Ghia

    2014-01-01

    Full Text Available Stewart-Bluefarb acroangiodermatitis is the occurrence of pseudo-kaposiform changes with an underlying arterio-venous malformation. Parkes-Weber syndrome is a triad of arterio-venous malformation with varicose veins with bony and soft-tissue hypertrophy involving the extremity. A 13 year-old-female presented with ulcerated growth with bleeding episodes on right leg since past four years. A reddish discoloration over right leg was noticed at four years of age which remained unchanged until nine years of age, after which it showed rapid increase in size along with disproportionate increase in length and girth of right lower limb. Examination revealed hyperpigmented soft verrucous plaque over the right lower one-third of leg, along with presence of ulcers and dilated tortuous veins in the right lower leg with thrill and bruit over the right popliteal and inguinal region. A differential diagnosis of verrucous hemangioma and arterio-venous malformation with pseudo-kaposiform change was considered. Skin biopsy showed multiple fenestrated capillaries with perivascular lymphocyte infiltrate suggestive of capillary malformations. X-ray showed osteolytic defect in right tibia. Duplex ultrasound and magnetic resonance imaging of right leg showed multiple fast flowing small and medium sized arterio-venous malformations of small to moderate size. Thus, on the basis of clinical and radiological features, we made a diagnosis of Stewart-Bluefarb type of acroangiodermatitis with Parkes-Weber syndrome. She was managed conservatively with compression stockings.

  3. The p53-reactivating small-molecule RITA enhances cisplatin-induced cytotoxicity and apoptosis in head and neck cancer.

    Science.gov (United States)

    Roh, Jong-Lyel; Ko, Jung Ho; Moon, Soo Jin; Ryu, Chang Hwan; Choi, Jun Young; Koch, Wayne M

    2012-12-01

    We evaluated whether the restoration of p53 function by the p53-reactivating small molecule RITA (reactivation of p53 and induction of tumor cell apoptosis enhances cisplatin-induced cytotoxicity and apoptosis in head-and-neck cancer (HNC). RITA induced prominent accumulation and reactivation of p53 in a wild-type TP53-bearing HNC cell line. RITA showed maximal growth suppression in tumor cells showing MDM2-dependent p53 degradation. RITA promoted apoptosis in association with upregulation of p21, BAX, and cleaved caspase-3; notably, the apoptotic response was blocked by pifithrin-α, demonstrating its p53 dependence. With increasing concentrations, RITA strongly induced apoptosis rather than G2-phase arrest. In combination therapy, RITA enhanced cisplatin-induced growth inhibition and apoptosis of HNC cells invitro and in vivo. Our data suggest that the restoration of p53 tumor-suppressive function by RITA enhances the cytotoxicity and apoptosis of cisplatin, an action that may offer an attractive strategy for treating HNC. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  4. The Recent Infection Testing Algorithm (RITA) in clinical practice: a survey of HIV clinicians in England and Northern Ireland.

    Science.gov (United States)

    Garrett, Nj; Lattimore, S; Gilbart, Vl; Aghaizu, A; Mensah, G; Tosswill, J; Murphy, G; Delpech, V

    2012-08-01

    In order to estimate HIV incidence among high-risk groups, in January 2009 the Health Protection Agency introduced the Recent Infection Testing Algorithm (RITA) in England and Northern Ireland (E&NI), currently the only regions to inform patients of RITA results. This survey of HIV specialists aimed to investigate the role of RITA in patient management and explore clinicians' views on its role in clinical practice and during partner notification. An online questionnaire was distributed to HIV specialists via the British HIV Association membership email list in February 2011. Forty-two HIV specialists from 32 HIV centres responded to the survey among 90 centres enrolled in the programme (response rate 36%). Testing for recent infection was considered standard of care by 83% of respondents, 80% felt confident in interpreting results and 92% discussed results with patients, particularly in the context of a possible HIV seroconversion illness (96%) or when deciding when to start antiretroviral therapy (70%). A third (36%) of specialists were initially concerned that RITA results may cause additional anxiety among patients; however, no adverse events were reported. The majority (90%) felt that results could assist with contact tracing by prioritizing patients with likely recent infection. However, only a few centres have currently incorporated RITA into their HIV partner notification protocols. RITA has been introduced into clinical practice with no reported patient adverse events. Access to results at centre level should be improved. National guidance regarding use of RITA as a tool for contact tracing is required. © 2012 British HIV Association.

  5. RITA enhances chemosensivity of pre-B ALL cells to doxorubicin by inducing p53-dependent apoptosis.

    Science.gov (United States)

    Kazemi, Ahmad; Safa, Majid; Shahbazi, Atefeh

    2011-07-01

    The use of low-molecular-weight, non-peptidic molecules that disrupt the interaction between the p53 tumor suppressor and its negative regulator MDM2 has provided a promising alternative for the treatment of different types of cancer. Here, we used small-molecule reactivation of p53 and induction of tumor cell apoptosis (RITA) to sensitize leukemic NALM-6 cells to doxorubicin by upregulating p53 protein. RITA alone effectively inhibited NALM-6 cells viability in dose-dependent manner as measured by 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide assay and induced apoptosis as evaluated by flow cytometry, whereas RITA in combination with doxorubicin enhanced NALM-6 cells to doxorubicin-sensitivity and promoted doxorubicin induced apoptosis. Levels of p53 protein and its proapoptotic target genes, quantified by western blot and real-time PCR respectively, showed that expression of p53 was significantly increased after RITA treatment. Using p53 inhibitors PFT-alpha and PFT-mu it was shown that p53-mediated apoptosis induced by RITA can be regulated by both p53-transcription-dependent and -independent pathways. Moreover, RITA-induced apoptosis was accompanied by the activation of caspase-3 and PARP cleavage. Therefore, exploiting synergistic effects between RITA and chemotherapeutics might be an effective clinical strategy for leukemia chemotherapy.

  6. Defining the buffering process by a triprotic acid without relying on Stewart-electroneutrality considerations.

    Science.gov (United States)

    Nguyen, Minhtri K; Kao, Liyo; Kurtz, Ira

    2011-08-17

    Upon the addition of protons to an aqueous solution, a component of the H+ load will be bound i.e. buffered. In an aqueous solution containing a triprotic acid, H+ can be bound to three different states of the acid as well as to OH- ions that are derived from the auto-ionization of H2O. In quantifying the buffering process of a triprotic acid, one must define the partitioning of H+ among the three states of the acid and also the OH- ions in solution in order to predict the equilibrium pH value. However, previous quantitative approaches that model triprotic acid titration behaviour and used to predict the equilibrium pH rely on the mathematical convenience of electroneutrality/charge balance considerations. This fact has caused confusion in the literature, and has led to the assumption that charge balance/electroneutrality is a causal factor in modulating proton buffering (Stewart formulation). However, as we have previously shown, although charge balance can be used mathematically as a convenient tool in deriving various formulae, electroneutrality per se is not a fundamental physicochemical parameter that is mechanistically involved in the underlying buffering and proton transfer reactions. The lack of distinction between a mathematical tool, and a fundamental physicochemical parameter is in part a reason for the current debate regarding the Stewart formulation of acid-base analysis. We therefore posed the following question: Is it possible to generate an equation that defines and predicts the buffering of a triprotic acid that is based only on H+ partitioning without incorporating electroneutrality in the derivation? Towards this goal, we derived our new equation utilizing: 1) partitioning of H+ buffering; 2) conservation of mass; and 3) acid-base equilibria. In validating this model, we compared the predicted equilibrium pH with the measured pH of an aqueous solution consisting of Na2HPO4 to which HCl was added. The measured pH values were in excellent agreement

  7. Defining the buffering process by a triprotic acid without relying on stewart-electroneutrality considerations

    Directory of Open Access Journals (Sweden)

    Kao Liyo

    2011-08-01

    Full Text Available Abstract Upon the addition of protons to an aqueous solution, a component of the H+ load will be bound i.e. buffered. In an aqueous solution containing a triprotic acid, H+ can be bound to three different states of the acid as well as to OH- ions that are derived from the auto-ionization of H2O. In quantifying the buffering process of a triprotic acid, one must define the partitioning of H+ among the three states of the acid and also the OH- ions in solution in order to predict the equilibrium pH value. However, previous quantitative approaches that model triprotic acid titration behaviour and used to predict the equilibrium pH rely on the mathematical convenience of electroneutrality/charge balance considerations. This fact has caused confusion in the literature, and has led to the assumption that charge balance/electroneutrality is a causal factor in modulating proton buffering (Stewart formulation. However, as we have previously shown, although charge balance can be used mathematically as a convenient tool in deriving various formulae, electroneutrality per se is not a fundamental physicochemical parameter that is mechanistically involved in the underlying buffering and proton transfer reactions. The lack of distinction between a mathematical tool, and a fundamental physicochemical parameter is in part a reason for the current debate regarding the Stewart formulation of acid-base analysis. We therefore posed the following question: Is it possible to generate an equation that defines and predicts the buffering of a triprotic acid that is based only on H+ partitioning without incorporating electroneutrality in the derivation? Towards this goal, we derived our new equation utilizing: 1 partitioning of H+ buffering; 2 conservation of mass; and 3 acid-base equilibria. In validating this model, we compared the predicted equilibrium pH with the measured pH of an aqueous solution consisting of Na2HPO4 to which HCl was added. The measured pH values

  8. Defining the buffering process by a triprotic acid without relying on stewart-electroneutrality considerations

    Science.gov (United States)

    2011-01-01

    Upon the addition of protons to an aqueous solution, a component of the H+ load will be bound i.e. buffered. In an aqueous solution containing a triprotic acid, H+ can be bound to three different states of the acid as well as to OH- ions that are derived from the auto-ionization of H2O. In quantifying the buffering process of a triprotic acid, one must define the partitioning of H+ among the three states of the acid and also the OH- ions in solution in order to predict the equilibrium pH value. However, previous quantitative approaches that model triprotic acid titration behaviour and used to predict the equilibrium pH rely on the mathematical convenience of electroneutrality/charge balance considerations. This fact has caused confusion in the literature, and has led to the assumption that charge balance/electroneutrality is a causal factor in modulating proton buffering (Stewart formulation). However, as we have previously shown, although charge balance can be used mathematically as a convenient tool in deriving various formulae, electroneutrality per se is not a fundamental physicochemical parameter that is mechanistically involved in the underlying buffering and proton transfer reactions. The lack of distinction between a mathematical tool, and a fundamental physicochemical parameter is in part a reason for the current debate regarding the Stewart formulation of acid-base analysis. We therefore posed the following question: Is it possible to generate an equation that defines and predicts the buffering of a triprotic acid that is based only on H+ partitioning without incorporating electroneutrality in the derivation? Towards this goal, we derived our new equation utilizing: 1) partitioning of H+ buffering; 2) conservation of mass; and 3) acid-base equilibria. In validating this model, we compared the predicted equilibrium pH with the measured pH of an aqueous solution consisting of Na2HPO4 to which HCl was added. The measured pH values were in excellent agreement

  9. Quantitative acid-base physiology using the Stewart model. Does it improve our understanding of what is really wrong?

    NARCIS (Netherlands)

    Derksen, R.; Scheffer, G.J.; Hoeven, J.G. van der

    2006-01-01

    Traditional theories of acid-base balance are based on the Henderson-Hasselbalch equation to calculate proton concentration. The recent revival of quantitative acid-base physiology using the Stewart model has increased our understanding of complicated acid-base disorders, but has also led to several

  10. Jon Stewart Comes to Class: The Learning Effects of "America (The Book)" in Introduction to American Government Courses

    Science.gov (United States)

    Baumgartner, Jody C.; Morris, Jonathan S.

    2008-01-01

    This project posits that incorporating political humor into the classroom can have a positive effect on learning in higher education. Specifically, we present preliminary findings from a quasi-experiment in which a humorous, "mock" textbook titled America (The Book) (Stewart, Karlin, and Javerbaum 2004) was incorporated into Introduction to…

  11. A preliminary report on coprolites from the Late Triassic part of the Kap Stewart Formation, Jameson Land, East Greenland

    DEFF Research Database (Denmark)

    Milàn, Jesper; Clemmensen, Lars B; Adolphsen, Jan Schulz

    2012-01-01

    The basal part of the Triassic-Jurassic (Rhaetian-Sinemurian) Kap Stewart Formation, exposed at Jameson Land, East Greenland, yields an extensive coprolite collection from black, parallel-laminated mudstone (“paper shale”), representing an open lacustrine system. Preliminary investigations show t...

  12. Toxicity and Safety Profiles of Methanolic Extract of Pistacia integerrima J. L. Stewart ex Brandis (PI for Wistar Rats

    Directory of Open Access Journals (Sweden)

    Gotmi Sharwan

    2016-09-01

    Full Text Available Objectives: The goals of this research were to evaluate acute (single-dose and sub-acute (repeated-dose toxicity profiles of methanolic extract of Pistacia integerrima J. L. Stewart ex Brandis (PI for Wistar rats and to assess the safety profile of PI by observing physiological changes, mortality, changes in body weight

  13. Optimal Kinematic Design of a 6-UCU Kind Gough-Stewart Platform with a Guaranteed Given Accuracy

    Directory of Open Access Journals (Sweden)

    Guojun Liu

    2018-06-01

    Full Text Available The 6-UCU (U-universal joint; C-cylinder joint kind Gough-Stewart platform is extensively employed in motion simulators due to its high accuracy, large payload, and high-speed capability. However, because of the manufacturing and assembling errors, the real geometry may be different from the nominal one. In the design process of the high-accuracy Gough-Stewart platform, one needs to consider these errors. The purpose of this paper is to propose an optimal design method for the 6-UCU kind Gough-Stewart platform with a guaranteed given accuracy. Accuracy analysis of the 6-UCU kind Gough-Stewart platform is presented by considering the limb length errors and joint position errors. An optimal design method is proposed by using a multi-objective evolutionary algorithm, the non-dominated sorting genetic algorithm II (NSGA-II. A set of Pareto-optimal parameters was found by applying the proposed optimal design method. An engineering design case was studied to verify the effectiveness of the proposed method.

  14. Rangeland livestock production: Developing the concept of sustainability on the Santa Rita Experimental Range

    Science.gov (United States)

    George B. Ruyle

    2003-01-01

    The Santa Rita Experimental Range (SRER) was established in 1903 at the behest of concerned stockmen and researchers as the first facility in the United States set aside to study range livestock production. At the time, severe overgrazing of the public domain had seriously reduced carrying capacities of Southwestern rangelands. Researchers on the SRER developed and...

  15. Archive and laboratory embedded in the landscape: Future of the Santa Rita Experimental Range

    Science.gov (United States)

    Thomas E. Sheridan

    2003-01-01

    The Santa Rita Experimental Range (SRER) is both an archive of past ecological research and a laboratory for continuing research embedded in the southern Arizona landscape. The scientific questions being asked there have changed over the last 100 years, but SRER with its monitoring stations and its legacy of repeat photography still offers a unique opportunity to study...

  16. Sweet resin bush on the Santa Rita Experimental Range: An eradication effort

    Science.gov (United States)

    Larry D. Howery; Bruce D. Munda; Dan G. Robinett; Harry H. Buck

    2003-01-01

    Sweet resin bush (Euryops subcarnosus DC ssp. vulgaris B. Nord; or, Euryops multifidis (L. f.) DC.), a South African shrub introduced to Arizona in the 1930s, was discovered on the Santa Rita Experimental Range (SRER) in 1998. Due to the threat of spread of this invasive plant and its potential to cause adverse environmental and economic effects, and because it posed a...

  17. 75 FR 22770 - Gary E. Hall and Rita Hall; Notice of Availability of Environmental Assessment

    Science.gov (United States)

    2010-04-30

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13652-000-Montana] Gary E. Hall and Rita Hall; Notice of Availability of Environmental Assessment April 22, 2010. In accordance with the National Environmental Policy Act of 1969, as amended, and the Federal Energy Regulatory...

  18. "Making Lemonade from Lemons:" Early Childhood Teacher Educators' Programmatic Responses to Hurricanes Katrina and Rita

    Science.gov (United States)

    DiCarlo, Cynthia F.; Burts, Diane C.; Buchanan, Teresa K.; Aghayan, Carol; Benedict, Joan

    2007-01-01

    This article describes how early childhood teacher education faculty at one university responded in the aftermath of hurricanes Katrina and Rita and used the disaster to enhance their undergraduate and graduate programs. They explain how they modeled developmentally appropriate practices while responding to community needs. Four companion articles…

  19. Vascular plants and a brief history of the Kiowa and Rita Blanca National Grasslands

    Science.gov (United States)

    Donald L. Hazlett; Michael H. Schiebout; Paulette L. Ford

    2009-01-01

    Administered by the USDA Forest Service, the Kiowa and Rita Blanca National Grasslands occupy 230,000 acres of public land extending from northeastern New Mexico into the panhandles of Oklahoma and Texas. A mosaic of topographic features including canyons, plateaus, rolling grasslands and outcrops supports a diverse flora. Eight hundred twenty six (826) species of...

  20. Inelastic neutron scattering experiments with the monochromatic imaging mode of the RITA-II spectrometer

    DEFF Research Database (Denmark)

    Bahl, Christian Robert Haffenden; Lefmann, Kim; Abrahamsen, Asger Bech

    2006-01-01

    Recently a monochromatic multiple data taking mode has been demonstrated for diffraction experiments using a RITA type cold neutron spectrometer with a multi-bladed analyser and a position-sensitive detector. Here, we show how this mode can be used in combination with a flexible radial collimator...

  1. Missed by the Mass Media: The Houma, Pointe-au-Chien, and Hurricanes Katrina and Rita

    Science.gov (United States)

    Collins, Robert Keith

    2008-01-01

    This case study investigates the media discourse from Houma and Pointe-au-Chien tribal leaders in Louisiana on their experiences with Hurricanes Katrina and Rita. One section briefly engages the discourse as discernable from the reports found in Native American and non-Native American news media. Included is a brief yet close examination of these…

  2. Lightcurves for Shape Modeling: 852 Wladilena, 1089 Tama, and 1180 Rita

    Science.gov (United States)

    Polishook, David

    2012-10-01

    The folded lightcurves and synodic periods of 852 Wladilena, 1089 Tama, and 1180 Rita are reported. The data are used by Hanus et al. (2012) to derive the rotation axis and to construct a shape model by applying the inversion lightcurve technique.

  3. REMOTE SENSING DAMAGE ASSESSMENT OF CHEMICAL PLANTS AND REFINERIES FOLLOWING HURRICANES KATRINA AND RITA

    Science.gov (United States)

    The massive destruction brought by Hurricanes Katrina and Rita also impacted the many chemical plants and refineries in the region. The achievement of this rapid analysis capability highlights the advancement of this technology for air quality assessment and monitoring. Case st...

  4. Rita Lobato: a primeira médica formada no Brasil

    Directory of Open Access Journals (Sweden)

    Francisco Bruno Lobo

    2017-04-01

    Dentre elas foi escolhida a primeira mulher que se diplomou em medicina em uma Faculdade brasileira: A Dra. Rita Lobato de Freitas . No dia 9 de junho, aniversário de seu nascimento, o referido sêlo entrou em circulação.

  5. Geology of Santa Rita Coal Basin, Rio Grande do Sul, Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Correa da Silva, Z.C.; Bortoluzzi, C.A.; Cazzulo-Klepzig, M.; Dias-Fabricio, M.E.; Guerra-Sommer, M.; Marques-Toigo, M.; Paim, P.S.G.; Piccoli, A.E.M.; Silva Filho, B.C.

    1984-04-01

    Data on the sedimentology, stratigraphy, palynology, coal petrography and geochemistry of the Santa Rita Coal Basin, Rio Grande do Sul, Brazil, are presented. The investigations were carried out on samples obtained from drill cores of the sedimentary rocks of Tubarao Supergroup, Lower Permian of Parana Basin. (25 refs.)

  6. The Impact of Hurricanes Katrina and Rita on Louisiana School Nurses

    Science.gov (United States)

    Broussard, Lisa; Myers, Rachel; Meaux, Julie

    2008-01-01

    In the fall of 2005, the coast of Louisiana was devastated by two hurricanes, Katrina and Rita. Not only did these natural disasters have detrimental effects for those directly in their path, the storms had an impact on the lives of everyone in Louisiana. The professional practice of many Louisiana school nurses was affected by several factors,…

  7. V/V/sub max/ test for QSOs: comments on the paper by Hawkins and Stewart

    International Nuclear Information System (INIS)

    Wills, D.

    1983-01-01

    Hawkins and Stewart's interpretation of the results of the V/V/sub max/ test for QSO samples is shown to be invalid. Their suggestion that the high values of V/V/sub max/ at small redshifts result from the exclusion of nearby QSOs from the samples is examined quantitatively for the well-studied 3CR sample, and shown to have a negligible effect on the results. Their claim that the values of V/V/sub max/ at larger redshifts indicate a uniform space density of QSOs is not true after an error in their calculations is corrected. Although the V/V/sub max/ test is less sensitive to space density evolution at large redshifts, current results are in good agreement with the hypothesis that a single density evolution law describes the observations out to a redshift of at least 2.5

  8. Quaternary tectonics and basin history of Pahrump and Stewart Valleys, Nevada and California

    International Nuclear Information System (INIS)

    Hoffard, J.L.

    1991-05-01

    The Pahrump fault system is an active fault system located in Pahrump and Stewart Valleys, Nevada and California, in the southern part of the Basin and Range Province. This system is 50 km long by 30 km wide and is comprised of three fault zones: the right-lateral East Nopah fault zone, the right-oblique Pahrump Valley fault zone, and the normal West Spring Mountains fault zone. All three zones have geomorphic evidence for late Quaternary activity. Analysis of active fault patterns and seismic reflection lines suggests that the Pahrump basin has had a two-stage genesis, an early history associated with a period of low angle detachment faulting probably active 10-15 Ma, and a more recent history related to the present dextral shear system, probably active post-4 Ma

  9. Phantom solution in a non-linear Israel-Stewart theory

    Science.gov (United States)

    Cruz, Miguel; Cruz, Norman; Lepe, Samuel

    2017-06-01

    In this paper we present a phantom solution with a big rip singularity in a non-linear regime of the Israel-Stewart formalism. In this framework it is possible to extend this causal formalism in order to describe accelerated expansion, where assumption of near equilibrium is no longer valid. We assume a flat universe filled with a single viscous fluid ruled by a barotropic EoS, p = ωρ, which can represent a late time accelerated phase of the cosmic evolution. The solution allows to cross the phantom divide without evoking an exotic matter fluid and the effective EoS parameter is always lesser than -1 and constant in time.

  10. Metal concentrations in schoolyard soils from New Orleans, Louisiana before and after Hurricanes Katrina and Rita.

    Science.gov (United States)

    Presley, Steven M; Abel, Michael T; Austin, Galen P; Rainwater, Thomas R; Brown, Ray W; McDaniel, Les N; Marsland, Eric J; Fornerette, Ashley M; Dillard, Melvin L; Rigdon, Richard W; Kendall, Ronald J; Cobb, George P

    2010-06-01

    The long-term environmental impact and potential human health hazards resulting from Hurricanes Katrina and Rita throughout much of the United States Gulf Coast, particularly in the New Orleans, Louisiana, USA area are still being assessed and realized after more than four years. Numerous government agencies and private entities have collected environmental samples from throughout New Orleans and found concentrations of contaminants exceeding human health screening values as established by the United States Environmental Protection Agency (USEPA) for air, soil, and water. To further assess risks of exposure to toxic concentrations of soil contaminants for citizens, particularly children, returning to live in New Orleans following the storms, soils collected from schoolyards prior to Hurricane Katrina and after Hurricane Rita were screened for 26 metals. Concentrations exceeding USEPA Regional Screening Levels (USEPA-RSL), total exposure, non-cancer endpoints, for residential soils for arsenic (As), iron (Fe), lead (Pb), and thallium (Tl) were detected in soil samples collected from schoolyards both prior to Hurricane Katrina and after Hurricane Rita. Approximately 43% (9/21) of schoolyard soils collected prior to Hurricane Katrina contained Pb concentrations greater than 400mgkg(-1), and samples from four schoolyards collected after Hurricane Rita contained detectable Pb concentrations, with two exceeding 1700mgkg(-1). Thallium concentrations exceeded USEPA-RSL in samples collected from five schoolyards after Hurricane Rita. Based upon these findings and the known increased susceptibility of children to the effects of Pb exposure, a more extensive assessment of the soils in schoolyards, public parks and other residential areas of New Orleans for metal contaminants is warranted. 2010 Elsevier Ltd. All rights reserved.

  11. Hurricane Rita Track Radar Image with Topographic Overlay

    Science.gov (United States)

    2005-01-01

    [figure removed for brevity, see original site] Animation About the animation: This simulated view of the potential effects of storm surge flooding on Galveston and portions of south Houston was generated with data from the Shuttle Radar Topography Mission. Although it is protected by a 17-foot sea wall against storm surges, flooding due to storm surges caused by major hurricanes remains a concern. The animation shows regions that, if unprotected, would be inundated with water. The animation depicts flooding in one-meter increments. About the image: The Gulf Coast from the Mississippi Delta through the Texas coast is shown in this satellite image from NASA's Moderate Resolution Imaging Spectroradiometer (MODIS) overlain with data from the Shuttle Radar Topography Mission (SRTM), and the predicted storm track for Hurricane Rita. The prediction from the National Weather Service was published Sept. 22 at 4 p.m. Central Time, and shows the expected track center in black with the lighter shaded area indicating the range of potential tracks the storm could take. Low-lying terrain along the coast has been highlighted using the SRTM elevation data, with areas within 15 feet of sea level shown in red, and within 30 feet in yellow. These areas are more at risk for flooding and the destructive effects of storm surge and high waves. Data used in this image were acquired by the Shuttle Radar Topography Mission aboard the Space Shuttle Endeavour, launched on Feb. 11, 2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect 3-D measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter (approximately 200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between NASA, the National Geospatial

  12. Alice-Anne Martin (1926 - 2016)

    CERN Multimedia

    2016-01-01

    Alice-Anne Martin, known as “Schu” from her maiden name Schubert, passed away on 8 January 2016.   (Image: Gérard Bertin) Hired the year CERN was founded, 1954, when the construction of the Laboratory had not even begun, Schu first worked at the Villa de Cointrin (a historic building now within the grounds of Geneva airport) as a secretary. In this role, she typed the convention between CERN and the Swiss Confederation, prepared by Stéphanie Tixier, as well as some of the "Yellow Reports" that have marked key points in the Laboratory’s history. For example, using a special typewriter with two keyboards – Latin and Greek – she typed the Yellow Report on the KAM theorem by Rolf Hagedorn. Schu also worked with Felix Bloch, the first Director-General of CERN, and later became the secretary of Herbert Coblenz, the first CERN librarian. She was head of the team that edited the proceedings of the ...

  13. Hurricane Rita Aerial Photography: High-Resolution Imagery of the Texas and Louisiana Gulf Coast After Landfall

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The imagery posted on this site is of the Texas and Louisiana Gulf Coast after Hurricane Rita made landfall. The regions photographed range from San Luis Pass, Texas...

  14. Final Technical Report, Wind Generator Project (Ann Arbor)

    Energy Technology Data Exchange (ETDEWEB)

    Geisler, Nathan [City of Ann Arbor, MI (United States)

    2017-03-20

    A Final Technical Report (57 pages) describing educational exhibits and devices focused on wind energy, and related outreach activities and programs. Project partnership includes the City of Ann Arbor, MI and the Ann Arbor Hands-on Museum, along with additional sub-recipients, and U.S. Department of Energy/Office of Energy Efficiency and Renewable Energy (EERE). Report relays key milestones and sub-tasks as well as numerous graphics and images of five (5) transportable wind energy demonstration devices and five (5) wind energy exhibits designed and constructed between 2014 and 2016 for transport and use by the Ann Arbor Hands-on Museum.

  15. Professor Anne Khademian named National Academy of Public Administration Fellow

    OpenAIRE

    Chadwick, Heather Riley

    2009-01-01

    Anne Khademian, professor with Virginia Tech's Center for Public Administration and Policy, School of Public and International Affairs, at the Alexandria, Va., campus has been elected a National Academy of Public Administration (NAPA) Fellow.

  16. Anne-Marie Sargueil: ilu on kasulik / intervjueerinud Emilie Toomela

    Index Scriptorium Estoniae

    Sargueil, Anne-Marie

    2015-01-01

    Prantsuse Disainiinstituudi juht Anne-Marie Sargueil rääkis prantsuse ja skandinaavia disainist, prantslaste disainieelistustest, uutest suundadest disaini valdkonnas, Eesti Tarbekunsti- ja Disainimuuseumis avatud näitusest "20 prantsuse disainiikooni"

  17. The Royal Summer Palace, Ferdinand I and Anne

    Czech Academy of Sciences Publication Activity Database

    Dobalová, Sylva

    2015-01-01

    Roč. 7, č. 2 (2015), s. 162-175 ISSN 1804-1132 Institutional support: RVO:68378033 Keywords : Anne of Jagiello * Prague Castle * Ferdinand I of Habsburg * olive tree * dynasticism Subject RIV: AL - Art, Architecture, Cultural Heritage

  18. Ehe seep Eesti moodi / Anneli Aasmäe

    Index Scriptorium Estoniae

    Aasmäe, Anneli, 1973-

    2008-01-01

    Produtsent Kristian Taska Kalev Spordis näidatav Venezuela seebiseriaali Eesti oludele mugandatud variant "Kalevi naised" : lavastaja Ingomar Vihman : osades Andrus Vaarik, Anne Reemann, Piret Kalda, Ken Saan jt.

  19. Application of ANN and fuzzy logic algorithms for streamflow ...

    Indian Academy of Sciences (India)

    1Department of Soil and Water Engineering, College of Technology and Engineering, Maharana Pratap. University of ... It was found that, ANN model performance improved with increasing .... algorithm uses supervised learning that provides.

  20. Optimising training data for ANNs with Genetic Algorithms

    OpenAIRE

    Kamp , R. G.; Savenije , H. H. G.

    2006-01-01

    International audience; Artificial Neural Networks (ANNs) have proved to be good modelling tools in hydrology for rainfall-runoff modelling and hydraulic flow modelling. Representative datasets are necessary for the training phase in which the ANN learns the model's input-output relations. Good and representative training data is not always available. In this publication Genetic Algorithms (GA) are used to optimise training datasets. The approach is tested with an existing hydraulic model in ...

  1. Optimising training data for ANNs with Genetic Algorithms

    OpenAIRE

    R. G. Kamp; R. G. Kamp; H. H. G. Savenije

    2006-01-01

    Artificial Neural Networks (ANNs) have proved to be good modelling tools in hydrology for rainfall-runoff modelling and hydraulic flow modelling. Representative datasets are necessary for the training phase in which the ANN learns the model's input-output relations. Good and representative training data is not always available. In this publication Genetic Algorithms (GA) are used to optimise training datasets. The approach is tested with an existing hydraulic model in The Netherlands. An...

  2. Geology of the plutonic basement rocks of Stewart Island, New Zealand

    International Nuclear Information System (INIS)

    Allibone, A.H.; Tulloch, A.J.

    2004-01-01

    Exposures of basement rocks on Stewart Island provide a c. 70 km long by 50 km wide map of part of the Median Batholith that spans the margin of the Western Province. Because of their distance from the present plate boundary, these rocks are relatively unaffected by Cenozoic tectonism, allowing examination of unmodified Carboniferous-Cretaceous relationships within the Median Batholith. Thirty individual plutons (>c.20 km 2 ) have been mapped along with numerous relatively small intrusions ( 2 ). The large plutons form 85-90% of the Median Batholith on Stewart Island while the many smaller intrusions comprise 10-15%, mostly in the north. Lithologies include: biotite ± minor hornblende granodiorite, granite and leucogranite with accessory titanite - magmatic epidote and allanite (c. 50%); biotite ± muscovite ± garnet granite with S-type affinities (c. 10%); alkaline quartz monzonite, granite, and alkali feldspar granite with rare aegirine and blue-green amphibole (c. 3%); quartz monzodiorite and diorite with hornblende > biotite (c. 23%); gabbro and anorthosite (c. 12%) and ultramafic rocks (c. 2%). U-Pb zircon and monazite dating indicates that c. 12% of these plutonic rocks were emplaced during the Carboniferous between 345 and 290 Ma, c. 20% in the Early-Middle Jurassic at c. 170-165 Ma, c. 30% in the latest Jurassic to earliest Cretaceous between 152 and 128 Ma, and c. 38% in the Early Cretaceous between 128 and 100 Ma. The distribution of Pegasus Group schists and peraluminous granitoid rocks indicates that the northern limit of extensive early Paleozoic Western Province basement is located either within the Gutter Shear Zone or at the Escarpment Fault, 10-15 km south of the Freshwater Fault System previously thought to mark this boundary. Carboniferous and Middle Jurassic magmatism extended plutonic basement northwards as far as the Freshwater Fault System, while further magmatism during the latest Jurassic and earliest Cretaceous produced the basement

  3. U-Pb ages of detrital zircon from Pegasus Group, Stewart Island

    International Nuclear Information System (INIS)

    Walker, N.; Tulloch, A.J.; Allibone, A.

    1998-01-01

    Stewart Island (New Zealand) is relatively unaffected by Cenozoic deformation related to the present-day plate boundary and has thus been a locale of investigations that focus on the relationship between Mesozoic continental margin magmatic rocks and the Western Province (WP) of NZ. Pegasus Group metasedimentary rocks represent the only candidate for WP equivalents on Stewart Island. We measured U-Pb and 207 Pb / 206 Pb ages of detrital zircons from the Pegasus Group in an effort to validate the correlation with the WP. On SI, Pegasus Group is exposed over a small area in the southern Tin Range where it forms amphibolite facies roof pendants and screens among plutons of mid Paleozoic to mid Cretaceous age. Mica schists predominate, with lesser amounts of psammite and metaquartzite and rare calcareous schist and amphibolite. Zircons were extracted from metaquarzite and 24 grains were chosen on the basis of morphology for geochronologic investigation. Sixteen single crystals were dated by U-Pb TIMS; 8 additional grains were studied by the total evaporation method described by Kober. Despite vigorous air abrasion prior to processing, the 16 grains measured by conventional U-Pb TIMS yielded slightly normally discordant ages that we interpret to reflect minor Pb-loss. The 8 grains studied by the total evaporation method yielded more than four analytically identical /sup 207 Pb / 206 Pb ages within each grain at progressively higher temperatures (1515-1580 degrees C) of evaporation. The results permit the following general conclusions: 1) the age range of 420-2700 Ma is grossly similar to that reported from the Greenland Group/Victoria Paragneiss (Ireland 1992) of the Buller Terrane, WP; 2) the zircon population is dominantly 530-680 Ma but a subsidiary population is 900-1100 Ma; 3) no zircons with ages that match the timing of the Ross Orogen (530-480 Ma) were identified; 4) two grains of 420 Ma and a 453 Ma are probably too young for the paleontogically

  4. Geographical and Temporal Dynamics of Chaetocnema Pulicaria Populations and Their Role in Stewart's Disease of Corn in Iowa

    International Nuclear Information System (INIS)

    Paul David Esker

    2001-01-01

    This thesis is organized into five chapters. Chapter 1 is the introduction and justification, chapters 2 and 3 are journal papers, chapter 4 is a preliminary analysis of winter environmental variables and their use in forecasting for Stewart's disease of corn, and chapter 5 is general conclusions and discussion. References can be found at the end of each chapter, except chapter 5 and are specific to that chapter

  5. An Axisymmetric View of Concentric Eyewall Evolution in Hurricane Rita (2005)

    Science.gov (United States)

    2012-08-01

    of Hurricane Hugo (1989). Mon. Wea. Rev., 136, 1237–1259. Martinez, Y., G. Brunet, and M. K. Yau, 2010: On the dynamics of two-dimensional hurricane ...An Axisymmetric View of Concentric Eyewall Evolution in Hurricane Rita (2005) MICHAEL M. BELL Naval Postgraduate School, Monterey, California, and... Hurricane Research Division, Miami, Florida WEN-CHAU LEE National Center for Atmospheric Research,* Boulder, Colorado (Manuscript received 23 June 2011, in

  6. Pharmacological targeting of p53 through RITA is an effective antitumoral strategy for malignant pleural mesothelioma.

    Science.gov (United States)

    Di Marzo, Domenico; Forte, Iris Maria; Indovina, Paola; Di Gennaro, Elena; Rizzo, Valeria; Giorgi, Francesca; Mattioli, Eliseo; Iannuzzi, Carmelina Antonella; Budillon, Alfredo; Giordano, Antonio; Pentimalli, Francesca

    2014-01-01

    Malignant mesothelioma, a very aggressive tumor associated to asbestos exposure, is expected to increase in incidence, and unfortunately, no curative modality exists. Reactivation of p53 is a new attractive antitumoral strategy. p53 is rarely mutated in mesothelioma, but it is inactivated in most tumors by the lack of p14(ARF). Here, we evaluated the feasibility of this approach in pleural mesothelioma by testing RITA and nutlin-3, two molecules able to restore p53 function through a different mechanism, on a panel of mesothelioma cell lines representing the epithelioid (NCI-H28, NCI-H2452, IST-MES 2), biphasic (MSTO-211H), and sarcomatoid (NCI-H2052) histotypes compared with the normal mesothelial HMC-hTERT. RITA triggered robust caspase-dependent apoptosis specifically in epithelioid and biphasic mesothelioma cell lines, both through wild-type and mutant p53, concomitant to p21 downregulation. Conversely, nutlin-3 induced a p21-dependent growth arrest, rather than apoptosis, and was slightly toxic on HMC-hTERT.   Interestingly, we identified a previously undetected point mutation of p53 (p.Arg249Ser) in IST-MES 2, and showed that RITA is also able to reactivate this p53 mutant protein and its apoptotic function. RITA reduced tumor growth in a MSTO-211H-derived xenograft model of mesothelioma and synergized with cisplatin, which is the mainstay of treatment for this tumor. Our data indicate that reactivation of p53 and concomitant p21 downregulation effectively induce cell death in mesothelioma, a tumor characterized by a high intrinsic resistance to apoptosis. Altogether, our findings provide the preclinical framework supporting the use of p53-reactivating agents alone, or in combination regimens, to improve the outcome of patients with mesothelioma.

  7. Integration of the virtual model of a Stewart platform with the avatar of a vehicle in a virtual reality

    Science.gov (United States)

    Herbuś, K.; Ociepka, P.

    2016-08-01

    The development of methods of computer aided design and engineering allows conducting virtual tests, among others concerning motion simulation of technical means. The paper presents a method of integrating an object in the form of a virtual model of a Stewart platform with an avatar of a vehicle moving in a virtual environment. The area of the problem includes issues related to the problem of fidelity of mapping the work of the analyzed technical mean. The main object of investigations is a 3D model of a Stewart platform, which is a subsystem of the simulator designated for driving learning for disabled persons. The analyzed model of the platform, prepared for motion simulation, was created in the “Motion Simulation” module of a CAD/CAE class system Siemens PLM NX. Whereas the virtual environment, in which the moves the avatar of the passenger car, was elaborated in a VR class system EON Studio. The element integrating both of the mentioned software environments is a developed application that reads information from the virtual reality (VR) concerning the current position of the car avatar. Then, basing on the accepted algorithm, it sends control signals to respective joints of the model of the Stewart platform (CAD).

  8. A Stewart isolator with high-static-low-dynamic stiffness struts based on negative stiffness magnetic springs

    Science.gov (United States)

    Zheng, Yisheng; Li, Qingpin; Yan, Bo; Luo, Yajun; Zhang, Xinong

    2018-05-01

    In order to improve the isolation performance of passive Stewart platforms, the negative stiffness magnetic spring (NSMS) is employed to construct high static low dynamic stiffness (HSLDS) struts. With the NSMS, the resonance frequencies of the platform can be reduced effectively without deteriorating its load bearing capacity. The model of the Stewart isolation platform with HSLDS struts is presented and the stiffness characteristic of its struts is studied firstly. Then the nonlinear dynamic model of the platform including both geometry nonlinearity and stiffness nonlinearity is established; and its simplified dynamic model is derived under the condition of small vibration. The effect of nonlinearity on the isolation performance is also evaluated. Finally, a prototype is built and the isolation performance is tested. Both simulated and experimental results demonstrate that, by using the NSMS, the resonance frequencies of the Stewart isolator are reduced and the isolation performance in all six directions is improved: the isolation frequency band is increased and extended to a lower-frequency level.

  9. Geographical and Temporal Dynamics of Chaetocnema Pulicaria and Their Role in Stewart's Disease of Corn in Iowa

    Energy Technology Data Exchange (ETDEWEB)

    Esker, Paul David [Iowa State Univ., Ames, IA (United States)

    2001-01-01

    This thesis investigated the biology and importance of the corn flea beetle vector and its role in the Stewart's disease of corn pathosystem. This was accomplished by determining the number of corn flea beetle generations that occur in Iowa and by quantifying the proportions of those populations found to be infested with the causal agent of Stewart's disease, pantoea stewartii. In addition, a preliminary study was conducted to determine how soil temperature was influenced by air temperature and how this may be applied to forecasting for Stewart's disease of corn. Research using yellow sticky cards and sweep netting demonstrated that there are overwintering, first, and second field generations of the corn flea beetle in Iowa. It was also observed that there was a period during June of both 1999 and 2000 when corn flea beetles were not found, which is important new management information. This research has also demonstrated that the incidence of P. stewartii-infested corn flea beetles can be monitored by ELISA testing and that the incidence fluctuates greatly throughout the corn growing season. The initial level of inoculum (P. stewartii-infested corn flea beetles in the adult overwintering generation) does not remain static during the spring as was previously hypothesized. This signals that additional research is needed concerning the mechanisms of fluctuation in the proportion of beetles infested with P. stewartii.

  10. PID Controllers Design Applied to Positioning of Ball on the Stewart Platform

    Directory of Open Access Journals (Sweden)

    Koszewnik Andrzej

    2014-12-01

    Full Text Available The paper presents the design and practical implementation of PID controllers for a Stewart platform. The platform uses a resistance touch panel as a sensor and servo motors as actuators. The complete control system stabilizing the ball on the platform is realized with the Arduino microcontroller and the Matlab/Simulink software. Two processes required to acquire measurement signals from the touch panel in two perpendicular directions X and Y, are discussed. The first process includes the calibration of the touch panel, and the second process - the filtering of measurement signals with the low pass Butterworth filter. The obtained signals are used to design the algorithm of the ball stabilization by decoupling the global system into two local subsystems. The algorithm is implemented in a soft real time system. The parameters of both PID controllers (PIDx and PIDy are tuned by the trial-error method and implemented in the microcontroller. Finally, the complete control system is tested at the laboratory stand.

  11. Crossing the phantom divide with dissipative normal matter in the Israel-Stewart formalism

    Science.gov (United States)

    Cruz, Norman; Lepe, Samuel

    2017-04-01

    A phantom solution in the framework of the causal Israel-Stewart (IS) formalism is discussed. We assume a late time behavior of the cosmic evolution by considering only one dominant matter fluid with viscosity. In the model it is assumed a bulk viscosity of the form ξ =ξ0ρ 1 / 2, where ρ is the energy density of the fluid. We evaluate and discuss the behavior of the thermodynamical parameters associated to this solution, like the temperature, rate of entropy, entropy, relaxation time, effective pressure and effective EoS. A discussion about the assumption of near equilibrium of the formalism and the accelerated expansion of the solution is presented. The solution allows to cross the phantom divide without evoking an exotic matter fluid and the effective EoS parameter is always lesser than -1 and time independent. A future singularity (big rip) occurs, but different from the Type I (big rip) solution classified in S. Nojiri, S.D. Odintsov and S. Tsujikawa (2005) [2], if we consider other thermodynamics parameters like, for example, the effective pressure in the presence of viscosity or the relaxation time.

  12. Polymetallic mineralised veins in ferroan/A-type Cretaceous leucogranite, Stewart Island, New Zealand

    International Nuclear Information System (INIS)

    Allibone, A.H.; MacKenzie, D.; Turnbull, R.E.; Tulloch, A.J.; Craw, D.; Palin, M.

    2016-01-01

    The 140±1 Ma hypersolvus, ferroan, weakly peralkaline to weakly peraluminous North Red Head leucogranite in northwest Stewart Island is cut by quartz-pyrite-rich veins that contain a wide variety of Mo, Ag, Te, Bi, Au, Co, Cu, Pb, Zn, REE, Nb, Y, Th, U, Zr, Ti, Be and F-bearing minerals. Patchy hematite-pyrite alteration locally overprints leucogranite in the vicinity of the mineralised veins. Individual veins are up to 5 m thick and 200+ m long. U-Pb dating and trace-element geochemistry indicate a direct link between leucogranite crystallisation and exsolution of the vein-forming hydrothermal fluid. Mineralised veins developed along transpressional faults within the leucogranite soon after emplacement. Incipiently mineralised quartz?±?pyrite veins at Waituna Bay and the northern end of West Ruggedy Beach several kilometres from North Red Head are probably part of the same hydrothermal system as the veins at North Red Head. Metal and alteration assemblages at North Red Head most closely resemble those in rare hydrothermal systems associated with oxidised fluorine-rich A-type granites. (author).

  13. Seat Adjustment Design of an Intelligent Robotic Wheelchair Based on the Stewart Platform

    Directory of Open Access Journals (Sweden)

    Po Er Hsu

    2013-03-01

    Full Text Available A wheelchair user makes direct contact with the wheelchair seat, which serves as the interface between the user and the wheelchair, for much of any given day. Seat adjustment design is of crucial importance in providing proper seating posture and comfort. This paper presents a multiple-DOF (degrees of freedom seat adjustment mechanism, which is intended to increase the independence of the wheelchair user while maintaining a concise structure, light weight, and intuitive control interface. This four-axis Stewart platform is capable of heaving, pitching, and swaying to provide seat elevation, tilt-in-space, and sideways movement functions. The geometry and types of joints of this mechanism are carefully arranged so that only one actuator needs to be controlled, enabling the wheelchair user to adjust the seat by simply pressing a button. The seat is also equipped with soft pressure-sensing pads to provide pressure management by adjusting the seat mechanism once continuous and concentrated pressure is detected. Finally, by comparing with the manual wheelchair, the proposed mechanism demonstrated the easier and more convenient operation with less effort for transfer assistance.

  14. Transforming an industrial giant. Interview by Thomas A. Stewart and Louise O'Brien.

    Science.gov (United States)

    von Pierer, Heinrich

    2005-02-01

    In his 12 years at the helm of Siemens, CEO Heinrich von Pierer designed and directed a major transformation. Taking this German icon from a technically superb but slow-moving industrial giantto a disciplined yet nimble multinational has posed enormous challenges. Since 1992, Siemens has revamped its portfolio of businesses, expanded its reach into 192 countries, and created a more local-market-driven culture, gaining recognition as one of the best-managed and most competitive companies in the world. In this edited interview with HBR editor Thomas A. Stewart and consulting editor Louise O'Brien, von Pierer describes the requirements for transformation and culture change and how he broke down historical barriers at Siemens. He shares his insights about portfolio restructuring, his lessons from competing with GE, and the pros and cons of being based in Europe versus America. He reflects on the true start of globalization after the fall of the Berlin wall and on how dramatically the company needed to change in order to counter the resulting pricing pressures across all of its businesses. He talks, too, about the biggest challenge on his successor's desk-"the particular challenge of China;" he says. Amid all these topics, von Pierer reiterates the importance of people: "We all talk about people as our most important resource, but as a matter of fact, who's really taking care of people?... We need [their] backing. We can't afford to run into a situation where people no longer accept what we do."

  15. Effects of marsh pond terracing on coastal wintering waterbirds before and after Hurricane Rita.

    Science.gov (United States)

    O'Connell, Jessica L; Nyman, John A

    2011-11-01

    From February to March 2005-2006, we surveyed wintering waterbirds to test effects of terracing on coastal pond use before and after Hurricane Rita. Marsh terracing is intended to slow coastal marsh loss in the Chenier Plain by slowing marsh erosion and encouraging vegetation expansion. Terraces also increase marsh edge in ponds, possibly benefiting waterbirds. We monitored paired terraced and unterraced ponds in three sites within southwestern Louisiana's Chenier Plain. Waterbirds were 75% more numerous in terraced than unterraced ponds. Waterbird richness was similar among ponds when corrected for number of individuals, suggesting terracing increased bird density but did not provide habitat unique from unterraced ponds. Birds were 93% more numerous following Hurricane Rita, mostly due to an influx of migrating waterfowl. Year round residents were similar in number before and after Hurricane Rita. Resident richness did not differ among years after correcting for number of observed individuals. Wading and dabbling foragers were more abundant in terraced ponds and these two guilds represented 74% of birds observed. We detected no difference among ponds for other guilds, i.e., probing, aerial, and diving foragers. Increasing proportion of mash edge increased bird density disproportionately: On average ponds with 10% edge had 6 birds observed and ponds with 30% edge had 16 birds observed. Terraces increased habitat interspersion and were an effective tool for increasing numbers of wintering waterfowl and wading birds. The extent to which terraces were sustainable following hurricane forces is unknown.

  16. Effects of Marsh Pond Terracing on Coastal Wintering Waterbirds Before and After Hurricane Rita

    Science.gov (United States)

    O'Connell, Jessica L.; Nyman, John A.

    2011-11-01

    From February to March 2005-2006, we surveyed wintering waterbirds to test effects of terracing on coastal pond use before and after Hurricane Rita. Marsh terracing is intended to slow coastal marsh loss in the Chenier Plain by slowing marsh erosion and encouraging vegetation expansion. Terraces also increase marsh edge in ponds, possibly benefiting waterbirds. We monitored paired terraced and unterraced ponds in three sites within southwestern Louisiana's Chenier Plain. Waterbirds were 75% more numerous in terraced than unterraced ponds. Waterbird richness was similar among ponds when corrected for number of individuals, suggesting terracing increased bird density but did not provide habitat unique from unterraced ponds. Birds were 93% more numerous following Hurricane Rita, mostly due to an influx of migrating waterfowl. Year round residents were similar in number before and after Hurricane Rita. Resident richness did not differ among years after correcting for number of observed individuals. Wading and dabbling foragers were more abundant in terraced ponds and these two guilds represented 74% of birds observed. We detected no difference among ponds for other guilds, i.e., probing, aerial, and diving foragers. Increasing proportion of mash edge increased bird density disproportionately: On average ponds with 10% edge had 6 birds observed and ponds with 30% edge had 16 birds observed. Terraces increased habitat interspersion and were an effective tool for increasing numbers of wintering waterfowl and wading birds. The extent to which terraces were sustainable following hurricane forces is unknown.

  17. SISTEM INFORMASI DAN PENGOLAHAN DATA GAJI KARYAWAN PADA RITA PASARAYA KEBONDALEM PURWOKERTO

    Directory of Open Access Journals (Sweden)

    Nyoman Heddy Triyodanta

    2009-02-01

    Full Text Available Penelitian ini berjudul "Sistem Informasi dan Pengolahan Data GajiKaryawan pada Rita Pasaraya Kebondalem Purwokerto". Tujuan dari penelitian iniodalah untuk mengetahui prosedur sistem informasi pengolahan data gaji karynvanyang sedang berjalan atau sedang dipakai pada Rita Pasaraya KebondalemPurwoketo, yang masih dilakukan dengan proses manual dan pada akhirnyadirancang suatu sistem informasi yang lebih baik. Merancang sistem informasi yangberbasis komputer untuk membantu mengatasi kelemahan dalam pengolahan datamenjadi informasi sesuai dengan kebutuhan user. Hasil analisis menunjukkan bahwapengolahan data di Rita Pasaraya Kebondalem Purwokerto mosih menggunakansistem manual. Sistem yang baru yaitu komputerisasi akan lebih tepat biladipergunakan untuk kehandalan data gaji karyawan. Selain sistem yang baru secarakomputerisasi kedisiplinan pemakai juga perlu ditingkatkan, secara fasilitastambahan selain ruangan khusus yaitu adanya Air Condisioner (AC pada ruangkomputer untuk membuat awet secara perangkat keras komputer dan komputer dapatdihidupkan secara terus menerus. Sistem yang baru aknn menambah kepercayaanImryawan dan pihak lain yang membutuhkan karena akurat, tepat dan handal. Sertapengambilan keputusan tentang kondisi data gaji karyawan dapat lebih alatrat dancepat yang tidak lain dapat meningkatkan kinerja karyawan terhadap perusahaan.

  18. Sediment deposition from Hurricane Rita on Hackberry Beach chenier in southwestern Louisiana: Chapter 6E in Science and the storms-the USGS response to the hurricanes of 2005

    Science.gov (United States)

    Faulkner, Stephen; Barrow, Wylie; Doyle, Thomas; Baldwin, Michael; Michot, Thomas; Wells, Christopher; Jeske, Clint

    2007-01-01

    Hurricane Rita significantly impacted the chenier forests of southwestern Louisiana, an important habitat for Neotropical migratory birds. Sediment deposition was measured along transects at Hackberry Beach chenier, and Rita's effects on chenier structure and morphology were determined.

  19. Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents.

    Science.gov (United States)

    Michaelis, M; Rothweiler, F; Agha, B; Barth, S; Voges, Y; Löschmann, N; von Deimling, A; Breitling, R; Doerr, H Wilhelm; Rödel, F; Speidel, D; Cinatl, J

    2012-04-05

    Adaptation of wild-type p53 expressing UKF-NB-3 cancer cells to the murine double minute 2 inhibitor nutlin-3 causes de novo p53 mutations at high frequency (13/20) and multi-drug resistance. Here, we show that the same cells respond very differently when adapted to RITA, a drug that, like nutlin-3, also disrupts the p53/Mdm2 interaction. All of the 11 UKF-NB-3 sub-lines adapted to RITA that we established retained functional wild-type p53 although RITA induced a substantial p53 response. Moreover, all RITA-adapted cell lines remained sensitive to nutlin-3, whereas only five out of 10 nutlin-3-adapted cell lines retained their sensitivity to RITA. In addition, repeated adaptation of the RITA-adapted sub-line UKF-NB-3(r)RITA(10 μM) to nutlin-3 resulted in p53 mutations. The RITA-adapted UKF-NB-3 sub-lines displayed no or less pronounced resistance to vincristine, cisplatin, and irradiation than nutlin-3-adapted UKF-NB-3 sub-lines. Furthermore, adaptation to RITA was associated with fewer changes at the expression level of antiapoptotic factors than observed with adaptation to nutlin-3. Transcriptomic analyses indicated the RITA-adapted sub-lines to be more similar at the gene expression level to the parental UKF-NB-3 cells than nutlin-3-adapted UKF-NB-3 sub-lines, which correlates with the observed chemotherapy and irradiation sensitivity phenotypes. In conclusion, RITA-adapted cells retain functional p53, remain sensitive to nutlin-3, and display a less pronounced resistance phenotype than nutlin-3-adapted cells.

  20. Anne Veski : "Ju siis ei ole minu rahvusvaheline kuulsus meie presidendi kõrvu jõudnud" / Anne Veski ; interv. Tiia Linnard

    Index Scriptorium Estoniae

    Veski, Anne, 1956-

    2008-01-01

    Laulja Anne Veski arutlusi kontserttegevusest Venemaal ja elust Eestis. Muuhulgas on juttu ka sellest, et Anne Veskit pole kunagi kutsutud presidendi iseseisvuspäeva vastuvõtule. Ilmunud ka: Severnoje Poberezhje 20. märts 2008, lk. 6

  1. Playing tag with ANN: boosted top identification with pattern recognition

    International Nuclear Information System (INIS)

    Almeida, Leandro G.; Backović, Mihailo; Cliche, Mathieu; Lee, Seung J.; Perelstein, Maxim

    2015-01-01

    Many searches for physics beyond the Standard Model at the Large Hadron Collider (LHC) rely on top tagging algorithms, which discriminate between boosted hadronic top quarks and the much more common jets initiated by light quarks and gluons. We note that the hadronic calorimeter (HCAL) effectively takes a “digital image" of each jet, with pixel intensities given by energy deposits in individual HCAL cells. Viewed in this way, top tagging becomes a canonical pattern recognition problem. With this motivation, we present a novel top tagging algorithm based on an Artificial Neural Network (ANN), one of the most popular approaches to pattern recognition. The ANN is trained on a large sample of boosted tops and light quark/gluon jets, and is then applied to independent test samples. The ANN tagger demonstrated excellent performance in a Monte Carlo study: for example, for jets with p T in the 1100–1200 GeV range, 60% top-tag efficiency can be achieved with a 4% mis-tag rate. We discuss the physical features of the jets identified by the ANN tagger as the most important for classification, as well as correlations between the ANN tagger and some of the familiar top-tagging observables and algorithms.

  2. Playing tag with ANN: boosted top identification with pattern recognition

    Energy Technology Data Exchange (ETDEWEB)

    Almeida, Leandro G. [Institut de Biologie de l’École Normale Supérieure (IBENS), Inserm 1024- CNRS 8197,46 rue d’Ulm, 75005 Paris (France); Backović, Mihailo [Center for Cosmology, Particle Physics and Phenomenology - CP3,Universite Catholique de Louvain,Louvain-la-neuve (Belgium); Cliche, Mathieu [Laboratory for Elementary Particle Physics, Cornell University,Ithaca, NY 14853 (United States); Lee, Seung J. [Department of Physics, Korea Advanced Institute of Science and Technology,335 Gwahak-ro, Yuseong-gu, Daejeon 305-701 (Korea, Republic of); School of Physics, Korea Institute for Advanced Study,Seoul 130-722 (Korea, Republic of); Perelstein, Maxim [Laboratory for Elementary Particle Physics, Cornell University,Ithaca, NY 14853 (United States)

    2015-07-17

    Many searches for physics beyond the Standard Model at the Large Hadron Collider (LHC) rely on top tagging algorithms, which discriminate between boosted hadronic top quarks and the much more common jets initiated by light quarks and gluons. We note that the hadronic calorimeter (HCAL) effectively takes a “digital image' of each jet, with pixel intensities given by energy deposits in individual HCAL cells. Viewed in this way, top tagging becomes a canonical pattern recognition problem. With this motivation, we present a novel top tagging algorithm based on an Artificial Neural Network (ANN), one of the most popular approaches to pattern recognition. The ANN is trained on a large sample of boosted tops and light quark/gluon jets, and is then applied to independent test samples. The ANN tagger demonstrated excellent performance in a Monte Carlo study: for example, for jets with p{sub T} in the 1100–1200 GeV range, 60% top-tag efficiency can be achieved with a 4% mis-tag rate. We discuss the physical features of the jets identified by the ANN tagger as the most important for classification, as well as correlations between the ANN tagger and some of the familiar top-tagging observables and algorithms.

  3. Dynamics of viscous cosmologies in the full Israel-Stewart formalism

    Science.gov (United States)

    Lepe, Samuel; Otalora, Giovanni; Saavedra, Joel

    2017-07-01

    A detailed dynamical analysis for a bulk viscosity model in the full Israel-Stewart formalism for a spatially flat Friedmann-Robertson-Walker universe is performed. In our study we have considered the total cosmic fluid constituted by radiation, dark matter, and dark energy. The dark matter fluid is treated as an imperfect fluid which has a bulk viscosity that depends on its energy density in the usual form ξ (ρm)=ξ0ρm1 /2, whereas the other components are assumed to behave as perfect fluids with constant equation of state parameter. We show that the thermal history of the Universe is reproduced provided that the viscous coefficient satisfies the condition ξ0≪1 , either for a zero or a suitable nonzero coupling between dark energy and viscous dark matter. In this case, the final attractor is a dark-energy-dominated, accelerating universe, with an effective equation of state parameter in the quintessence-like, cosmological constant-like, or phantom-like regime, in agreement with observations. As our main result, we show that in order to obtain a viable cosmological evolution and at the same time alleviating the cosmological coincidence problem via the mechanism of scaling solution, an explicit interaction between dark energy and viscous dark matter seems inevitable. This result is consistent with the well-known fact that models where dark matter and dark energy interact with each other have been proposed to solve the coincidence problem. Furthermore, by insisting on above, we show that in the present context a phantom nature of this interacting dark energy fluid is also favored.

  4. LFC based adaptive PID controller using ANN and ANFIS techniques

    Directory of Open Access Journals (Sweden)

    Mohamed I. Mosaad

    2014-12-01

    Full Text Available This paper presents an adaptive PID Load Frequency Control (LFC for power systems using Neuro-Fuzzy Inference Systems (ANFIS and Artificial Neural Networks (ANN oriented by Genetic Algorithm (GA. PID controller parameters are tuned off-line by using GA to minimize integral error square over a wide-range of load variations. The values of PID controller parameters obtained from GA are used to train both ANFIS and ANN. Therefore, the two proposed techniques could, online, tune the PID controller parameters for optimal response at any other load point within the operating range. Testing of the developed techniques shows that the adaptive PID-LFC could preserve optimal performance over the whole loading range. Results signify superiority of ANFIS over ANN in terms of performance measures.

  5. Effects of hurricanes Katrina and Rita on the chemistry of bottom sediments in Lake Pontchartrain, Louisiana, USA

    Science.gov (United States)

    Van Metre, P.C.; Horowitz, A.J.; Mahler, B.J.; Foreman, W.T.; Fuller, C.C.; Burkhardt, M.R.; Elrick, K.A.; Furlong, E.T.; Skrobialowski, S.C.; Smith, J.J.; Wilson, J.T.; Zaugg, S.D.

    2006-01-01

    The effects of Hurricanes Katrina and Rita and the subsequent unwatering of New Orleans, Louisiana, on the sediment chemistry of Lake Pontchartrain were evaluated by chemical analysis of samples of street mud and suspended and bottom sediments. The highest concentrations of urban-related elements and compounds (e.g., Pb, Zn, polycyclic aromatic hydrocarbons, and chlordane) in bottom sediments exceeded median concentrations in U.S. urban lakes and sediment-quality guidelines. The extent of the elevated concentrations was limited, however, to within a few hundred meters of the mouth of the 17th Street Canal, similar to results of historical assessments. Chemical and radionuclide analysis of pre- and post-Hurricane Rita samples indicates that remobilization of near-shore sediment by lake currents and storms is an ongoing process. The effects of Hurricanes Katrina and Rita on the sediment chemistry of Lake Pontchartrain are limited spatially and are most likely transitory. ?? 2006 American Chemical Society.

  6. Damage to offshore infrastructure in the Gulf of Mexico by hurricanes Katrina and Rita

    Science.gov (United States)

    Cruz, A. M.; Krausmann, E.

    2009-04-01

    The damage inflicted by hurricanes Katrina and Rita to the Gulf-of-Mexico's (GoM) oil and gas production, both onshore and offshore, has shown the proneness of industry to Natech accidents (natural hazard-triggered hazardous-materials releases). In order to contribute towards a better understanding of Natech events, we assessed the damage to and hazardous-materials releases from offshore oil and natural-gas platforms and pipelines induced by hurricanes Katrina and Rita. Data was obtained through a review of published literature and interviews with government officials and industry representatives from the affected region. We also reviewed over 60,000 records of reported hazardous-materials releases from the National Response Center's (NRC) database to identify and analyze the hazardous-materials releases directly attributed to offshore oil and gas platforms and pipelines affected by the two hurricanes. Our results show that hurricanes Katrina and Rita destroyed at least 113 platforms, and severely damaged at least 53 others. Sixty percent of the facilities destroyed were built 30 years ago or more prior to the adoption of the more stringent design standards that went into effect after 1977. The storms also destroyed 5 drilling rigs and severely damaged 19 mobile offshore drilling units (MODUs). Some 19 MODUs lost their moorings and became adrift during the storms which not only posed a danger to existing facilities but the dragging anchors also damaged pipelines and other infrastructure. Structural damage to platforms included toppling of sections, and tilting or leaning of platforms. Possible causes for failure of structural and non-structural components of platforms included loading caused by wave inundation of the deck. Failure of rigs attached to platforms was also observed resulting in significant damage to the platform or adjacent infrastructure, as well as damage to equipment, living quarters and helipads. The failures are attributable to tie-down components

  7. Lessons learned from the deadly sisters: drug and alcohol treatment disruption, and consequences from Hurricanes Katrina and Rita.

    Science.gov (United States)

    Maxwell, Jane Carlisle; Podus, Deborah; Walsh, David

    2009-01-01

    This paper reports on the effects of Hurricanes Katrina and Rita on drug and alcohol treatment in Texas in 2005-2006. Findings are based on a secondary analysis of administrative data on 567 hurricane-related admissions and on interview data from a sample of 20 staff in 11 treatment programs. Katrina evacuees differed from Rita clients in terms of demographics and primary problem substances and treatment needs, while the experiences of program staff and needed changes to improve disaster readiness were more similar. Additional systematic research is needed to document the intermediate and long-term impacts of the storms in these and other affected areas.

  8. Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma.

    Science.gov (United States)

    Saha, Manujendra N; Jiang, Hua; Yang, Yijun; Zhu, Xiaoyun; Wang, Xiaoming; Schimmer, Aaron D; Qiu, Lugui; Chang, Hong

    2012-01-01

    The low frequency of p53 alterations e.g., mutations/deletions (∼10%) in multiple myeloma (MM) makes this tumor type an ideal candidate for p53-targeted therapies. RITA is a small molecule which can induce apoptosis in tumor cells by activating the p53 pathway. We previously showed that RITA strongly activates p53 while selectively inhibiting growth of MM cells without inducing genotoxicity, indicating its potential as a drug lead for p53-targeted therapy in MM. However, the molecular mechanisms underlying the pro-apoptotic effect of RITA are largely undefined. Gene expression analysis by microarray identified a significant number of differentially expressed genes associated with stress response including c-Jun N-terminal kinase (JNK) signaling pathway. By Western blot analysis we further confirmed that RITA induced activation of p53 in conjunction with up-regulation of phosphorylated ASK-1, MKK-4 and c-Jun. These results suggest that RITA induced the activation of JNK signaling. Chromatin immunoprecipitation (ChIP) analysis showed that activated c-Jun binds to the activator protein-1 (AP-1) binding site of the p53 promoter region. Disruption of the JNK signal pathway by small interfering RNA (siRNA) against JNK or JNK specific inhibitor, SP-600125 inhibited the activation of p53 and attenuated apoptosis induced by RITA in myeloma cells carrying wild type p53. On the other hand, p53 transcriptional inhibitor, PFT-α or p53 siRNA not only inhibited the activation of p53 transcriptional targets but also blocked the activation of c-Jun suggesting the presence of a positive feedback loop between p53 and JNK. In addition, RITA in combination with dexamethasone, known as a JNK activator, displays synergistic cytotoxic responses in MM cell lines and patient samples. Our study unveils a previously undescribed mechanism of RITA-induced p53-mediated apoptosis through JNK signaling pathway and provides the rationale for combination of p53 activating drugs with JNK

  9. Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma.

    Directory of Open Access Journals (Sweden)

    Manujendra N Saha

    Full Text Available The low frequency of p53 alterations e.g., mutations/deletions (∼10% in multiple myeloma (MM makes this tumor type an ideal candidate for p53-targeted therapies. RITA is a small molecule which can induce apoptosis in tumor cells by activating the p53 pathway. We previously showed that RITA strongly activates p53 while selectively inhibiting growth of MM cells without inducing genotoxicity, indicating its potential as a drug lead for p53-targeted therapy in MM. However, the molecular mechanisms underlying the pro-apoptotic effect of RITA are largely undefined. Gene expression analysis by microarray identified a significant number of differentially expressed genes associated with stress response including c-Jun N-terminal kinase (JNK signaling pathway. By Western blot analysis we further confirmed that RITA induced activation of p53 in conjunction with up-regulation of phosphorylated ASK-1, MKK-4 and c-Jun. These results suggest that RITA induced the activation of JNK signaling. Chromatin immunoprecipitation (ChIP analysis showed that activated c-Jun binds to the activator protein-1 (AP-1 binding site of the p53 promoter region. Disruption of the JNK signal pathway by small interfering RNA (siRNA against JNK or JNK specific inhibitor, SP-600125 inhibited the activation of p53 and attenuated apoptosis induced by RITA in myeloma cells carrying wild type p53. On the other hand, p53 transcriptional inhibitor, PFT-α or p53 siRNA not only inhibited the activation of p53 transcriptional targets but also blocked the activation of c-Jun suggesting the presence of a positive feedback loop between p53 and JNK. In addition, RITA in combination with dexamethasone, known as a JNK activator, displays synergistic cytotoxic responses in MM cell lines and patient samples. Our study unveils a previously undescribed mechanism of RITA-induced p53-mediated apoptosis through JNK signaling pathway and provides the rationale for combination of p53 activating drugs with

  10. Dissolved and colloidal trace elements in the Mississippi River Delta outflow after Hurricanes Katrina and Rita

    Science.gov (United States)

    Shim, Moo-Joon; Swarzenski, Peter W.; Shiller, Alan M.

    2012-01-01

    The Mississippi River delta outflow region is periodically disturbed by tropical weather systems including major hurricanes, which can terminate seasonal bottom water hypoxia and cause the resuspension of shelf bottom sediments which could result in the injection of trace elements into the water column. In the summer of 2005, Hurricanes Katrina and Rita passed over the Louisiana Shelf within a month of each other. Three weeks after Rita, we collected water samples in the Mississippi River delta outflow, examining the distributions of trace elements to study the effect of Hurricanes Katrina and Rita. We observed limited stratification on the shelf and bottom waters that were no longer hypoxic. This resulted, for instance, in bottom water dissolved Mn being lower than is typically observed during hypoxia, but with concentrations still compatible with Mn–O2 trends previously reported. Interestingly, for no element were we able to identify an obvious effect of sediment resuspension on its distribution. In general, elemental distributions were compatible with previous observations in the Mississippi outflow system. Co and Re, which have not been reported for this system previously, showed behavior consistent with other systems: input for Co likely from desorption and conservative mixing for Re. For Cs, an element for which there is little information regarding its estuarine behavior, conservative mixing was also observed. Our filtration method, which allowed us to distinguish the dissolved (<0.02 μm) from colloidal (0.02–0.45 μm) phase, revealed significant colloidal fractions for Fe and Zn, only. For Fe, the colloidal phase was the dominant fraction and was rapidly removed at low salinity. Dissolved Fe, in contrast, persisted out to mid-salinities, being removed in a similar fashion to nitrate. This ability to distinguish the smaller Fe (likely dominantly organically complexed) from larger colloidal suspensates may be useful in better interpreting the

  11. The effect of proximity to hurricanes Katrina and Rita on subsequent hurricane outlook and optimistic bias.

    Science.gov (United States)

    Trumbo, Craig; Lueck, Michelle; Marlatt, Holly; Peek, Lori

    2011-12-01

    This study evaluated how individuals living on the Gulf Coast perceived hurricane risk after Hurricanes Katrina and Rita. It was hypothesized that hurricane outlook and optimistic bias for hurricane risk would be associated positively with distance from the Katrina-Rita landfall (more optimism at greater distance), controlling for historically based hurricane risk and county population density, demographics, individual hurricane experience, and dispositional optimism. Data were collected in January 2006 through a mail survey sent to 1,375 households in 41 counties on the coast (n = 824, 60% response). The analysis used hierarchal regression to test hypotheses. Hurricane history and population density had no effect on outlook; individuals who were male, older, and with higher household incomes were associated with lower risk perception; individual hurricane experience and personal impacts from Katrina and Rita predicted greater risk perception; greater dispositional optimism predicted more optimistic outlook; distance had a small effect but predicted less optimistic outlook at greater distance (model R(2) = 0.21). The model for optimistic bias had fewer effects: age and community tenure were significant; dispositional optimism had a positive effect on optimistic bias; distance variables were not significant (model R(2) = 0.05). The study shows that an existing measure of hurricane outlook has utility, hurricane outlook appears to be a unique concept from hurricane optimistic bias, and proximity has at most small effects. Future extension of this research will include improved conceptualization and measurement of hurricane risk perception and will bring to focus several concepts involving risk communication. © 2011 Society for Risk Analysis.

  12. Dissolved and colloidal trace elements in the Mississippi River delta outflow after Hurricanes Katrina and Rita

    Science.gov (United States)

    Shim, Moo-Joon; Swarzenski, Peter W.; Shiller, Alan M.

    2012-07-01

    The Mississippi River delta outflow region is periodically disturbed by tropical weather systems including major hurricanes, which can terminate seasonal bottom water hypoxia and cause the resuspension of shelf bottom sediments which could result in the injection of trace elements into the water column. In the summer of 2005, Hurricanes Katrina and Rita passed over the Louisiana Shelf within a month of each other. Three weeks after Rita, we collected water samples in the Mississippi River delta outflow, examining the distributions of trace elements to study the effect of Hurricanes Katrina and Rita. We observed limited stratification on the shelf and bottom waters that were no longer hypoxic. This resulted, for instance, in bottom water dissolved Mn being lower than is typically observed during hypoxia, but with concentrations still compatible with Mn-O2 trends previously reported. Interestingly, for no element were we able to identify an obvious effect of sediment resuspension on its distribution. In general, elemental distributions were compatible with previous observations in the Mississippi outflow system. Co and Re, which have not been reported for this system previously, showed behavior consistent with other systems: input for Co likely from desorption and conservative mixing for Re. For Cs, an element for which there is little information regarding its estuarine behavior, conservative mixing was also observed. Our filtration method, which allowed us to distinguish the dissolved (<0.02 μm) from colloidal (0.02-0.45 μm) phase, revealed significant colloidal fractions for Fe and Zn, only. For Fe, the colloidal phase was the dominant fraction and was rapidly removed at low salinity. Dissolved Fe, in contrast, persisted out to mid-salinities, being removed in a similar fashion to nitrate. This ability to distinguish the smaller Fe (likely dominantly organically complexed) from larger colloidal suspensates may be useful in better interpreting the bioavailablity

  13. ANNE TONER. Ellipsis in English Literature: Signs of Omission

    DEFF Research Database (Denmark)

    Lupton, Tina Jane

    2016-01-01

    As a freshman, I once met a PhD Student writing about the use of the comma in Jane Austen. For years the thesis topic kept me entertained as an example of how narrowly focused literary study could become. Reading Anne Toner's Ellipsis in English Literature commits me to a recantation of that joke...

  14. Eesti NATO ukselävel / Mari-Ann Kelam

    Index Scriptorium Estoniae

    Kelam, Mari-Ann, 1946-

    2002-01-01

    Seda, et NATO liitumisläbirääkimistele kutsutavate seas on ka Eesti, saab veel tänagi pidada üheks meie iseseisva riikluse suursaavutuseks, kui mitte imeks, kirjutab Riigikogu liige Mari-Ann Kelam. Autor: Isamaaliit. Parlamendisaadik

  15. Klaas ja mõis / Maie-Ann Raun

    Index Scriptorium Estoniae

    Raun, Maie-Ann, 1938-

    2007-01-01

    Klaasikunstinäitus "Ringkäik" Albu mõisas, kuraatorid Virve Kiil, Kati Kerstna, Kairi Orgusaar. Eksponeeritakse Tiina Sarapu, Mare Saare, Eeva Käsperi, Kai Kiudsoo-Värvi, Pilvi Ojamaa, Merle Bukoveci, Kalli Seina, Viivi-Ann Keerdo, Liisi Junolaineni, Kristiina Uslari, Ivo Lille töid

  16. 2011 : Qu'elle année !

    CERN Multimedia

    Staff Association

    2012-01-01

    « Quelle année ! Et quelle fin d’année ! La star de l’année a été le LHC, avec ses expériences, qui une fois de plus ont été sous les feux de la rampe. Mais on doit aussi citer toute une troupe d’acteurs importants, dans des domaines aussi différents que l’antimatière et l’expérience CLOUD. » Voilà ce que le Directeur général nous a écrit le 20 décembre dans son message avec ses vœux de fin d’année. Sans oublier, bien sûr, les fameux neutrinos hyperrapides vers Gran Sasso qui ont mis le CERN sur le devant de la scène mondiale. Ces succès qui font la fierté et la force de l’Organisation ont été rendus possibles «&...

  17. Why philosophy and history matter : A conversation with Ann Taves

    NARCIS (Netherlands)

    von Stuckrad, C.K.M.

    2010-01-01

    The article picks up some ideas that Ann Taves presents in her book Religious Experience Reconsidered, and looks at possible conversations that are not fleshed out in detail in Taves' book. In particular, it is argued that the disciplinary confrontation with philosophy and with historiography is of

  18. Ants Orasest ja Anne Lange monograafiast / Jüri Talvet

    Index Scriptorium Estoniae

    Talvet, Jüri, 1945-

    2005-01-01

    Arvustus: Oras, Ants. Luulekool. I, Apoloogia / koostajad Hando Runnel ja Jaak Rähesoo. Tartu : Ilmamaa, 2003 ; Oras, Ants. Luulekool II, Meistriklass. Tartu : Ilmamaa, 2004 ; Lange, Anne. Ants Oras : [kirjandusteadlane, -kriitik ja tõlkija (1900-1982)]. Tartu : Ilmamaa, 2004

  19. Vene ja prantsuse kunsti imetlemisest Londonis / Ann Alari

    Index Scriptorium Estoniae

    Alari, Ann

    2008-01-01

    Näitus "Venemaalt pärit prantsuse ja vene shedöövrid" kuningliku kunstiakadeemia saalides Londonis. Vaatluse all oli ajavahemik 1870 kuni 1925. Tööd olid pärit Moskvas elanud tekstiilitöösturitest suurärimeeste Sergei Shtshukini ja Ivan Morozovi kogudest, mis 1917. a. natsionaliseeriti. Kuraator Ann Dumas

  20. 2016-2017 Travel Expense Reports for Margaret Ann Biggs ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Beata Bialic

    Purpose: Internal IDRC meetings. Date(s):. 2016-07-04 to 2016-07-06. Destination(s):. Ottawa. Airfare: $0.00. Other. Transportation: $39.00. Accommodation: $0.00. Meals and. Incidentals: $25.43. Other: $0.00. Total: $64.43. Comments: 2016-2017 Travel Expense Reports for. Margaret Ann Biggs, Chairperson.

  1. 2016-2017 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Beata Bialic

    Purpose: Board meetings. Date(s):. 2016-11-20 to 2016-11-23. Destination(s):. Ottawa. Airfare: $445.14. Other. Transportation: $29.05. Accommodation: $786.80. Meals and. Incidentals: $76.79. Other: $0.00. Total: $1,337.78. Comments: 2016-2017 Travel Expense Reports for Mary. Anne Chambers, Governor, Chairperson ...

  2. 2017-2018 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    Ottawa. Airfare: $368.41. Other. Transportation: $69.95. Accommodation: $542.79. Meals and. Incidentals: $164.42. Other: $0.00. Total: $1,145.57. Comments: From residence in Thornhill, Ontario. 2017-2018 Travel Expense Reports for Mary. Anne Chambers, Governor, Chairperson of the. Human Resources Committee.

  3. 2016-2017 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Beata Bialic

    Date(s):. 2016-07-06. Destination(s):. Ottawa. Airfare: $482.11. Other. Transportation: $64.30. Accommodation: $0.00. Meals and. Incidentals: $25.28. Other: $0.00. Total: $571.69. Comments: 2016-2017 Travel Expense Reports for Mary. Anne Chambers, Governor, Chairperson of the. Human Resources Committee.

  4. 2016-2017 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Beata Bialic

    Date(s):. 2016-08-14 to 2016-08-23. Destination(s):. Peru/Colombia. Airfare: $3,484.87. Other. Transportation: $0.00. Accommodation: $1,942.21. Meals and. Incidentals: $395.27. Other: $75.50. Total: $5,897.85. Comments: 2016-2017 Travel Expense Reports for Mary. Anne Chambers, Governor, Chairperson of the.

  5. 2017-2018 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    Ottawa. Airfare: $563.72. Other. Transportation: $74.26. Accommodation: $0.00. Meals and. Incidentals: $46.17. Other: $30.00. Total: $714.15. Comments: From residence in Thornhill, Ontario. 2017-2018 Travel Expense Reports for Mary. Anne Chambers, Governor, Chairperson of the. Human Resources Committee.

  6. 2016-2017 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    chantal taylor

    Purpose: Board meetings. Date(s):. 2017-03-19 to 2017-03-22. Destination(s):. Ottawa. Airfare: $121.05. Other. Transportation: $51.92. Accommodation: $926.48. Meals and. Incidentals: $190.40. Other: $0.00. Total: $1,289.85. Comments: 2016-2017 Travel Expense Reports for Mary. Anne Chambers, Governor ...

  7. Q&A: Grace Anne Koppel, Living Well with COPD

    Science.gov (United States)

    ... their own lives back is the most rewarding thing we have ever done. Read More "The Challenge of COPD" Articles Q&A: Grace Anne Koppel, Living Well with COPD / What is COPD? / What Causes COPD? / Getting Tested / Am I at Risk? / COPD Quiz Fall ...

  8. Hiina tervendus / kommenteerivad Anne, Julia, Weihong Song, Fagang Ren

    Index Scriptorium Estoniae

    2013-01-01

    Tallinnas Tulika 19 asuvast Bai Lan Hiina massaažisalongist, kus ravitakse kuputeraapia, gua sha kraapimisplaatide, moksa, nõelravi ja punktmassaaži abil. Tui na massaaži ja hiina loodusteraapia protseduure kommenteerivad spetsialistid ning patsiendid Anne ja Julia

  9. Application of ANN and fuzzy logic algorithms for streamflow ...

    Indian Academy of Sciences (India)

    The present study focusses on development of models using ANN and fuzzy logic (FL) algorithm for predicting the streamflow for catchment of Savitri River Basin. The input vector to these models were daily rainfall, mean daily evaporation, mean daily temperature and lag streamflow used. In the present study, 20 years ...

  10. Solar radiation modelling using ANNs for different climates in China

    International Nuclear Information System (INIS)

    Lam, Joseph C.; Wan, Kevin K.W.; Yang, Liu

    2008-01-01

    Artificial neural networks (ANNs) were used to develop prediction models for daily global solar radiation using measured sunshine duration for 40 cities covering nine major thermal climatic zones and sub-zones in China. Coefficients of determination (R 2 ) for all the 40 cities and nine climatic zones/sub-zones are 0.82 or higher, indicating reasonably strong correlation between daily solar radiation and the corresponding sunshine hours. Mean bias error (MBE) varies from -3.3 MJ/m 2 in Ruoqiang (cold climates) to 2.19 MJ/m 2 in Anyang (cold climates). Root mean square error (RMSE) ranges from 1.4 MJ/m 2 in Altay (severe cold climates) to 4.01 MJ/m 2 in Ruoqiang. The three principal statistics (i.e., R 2 , MBE and RMSE) of the climatic zone/sub-zone ANN models are very close to the corresponding zone/sub-zone averages of the individual city ANN models, suggesting that climatic zone ANN models could be used to estimate global solar radiation for locations within the respective zones/sub-zones where only measured sunshine duration data are available. (author)

  11. Rita Thalmann (1926-2013), Pioneer of Women’s History

    OpenAIRE

    Hoock-Demarle, Marie-Claire

    2017-01-01

    Born in Nuremberg to a German-Jewish father and a Swiss-Jewish mother, Rita Thalmann fled the Nazi regime with her family in 1933, first taking refuge in Switzerland and then in France. After losing both her father (denounced and deported to Auschwitz), and her mother (who died of malnutrition while interned in Dijon), she survived the war through a support network organized by the headmistress of Dijon’s girls’ lycée, Marcelle Pardé, a member of the Resistance later deported to Ravensbrück. ...

  12. External factors impacting hospital evacuations caused by Hurricane Rita: the role of situational awareness.

    Science.gov (United States)

    Downey, Erin L; Andress, Knox; Schultz, Carl H

    2013-06-01

    The 2005 Gulf Coast hurricane season was one of the most costly and deadly in US history. Hurricane Rita stressed hospitals and led to multiple, simultaneous evacuations. This study systematically identified community factors associated with patient movement out of seven hospitals evacuated during Hurricane Rita. This study represents the second of two systematic, observational, and retrospective investigations of seven acute care hospitals that reported off-site evacuations due to Hurricane Rita. Participants from each hospital included decision makers that comprised the Incident Management Team (IMT). Investigators applied a standardized interview process designed to assess evacuation factors related to external situational awareness of community activities during facility evacuation due to hurricanes. The measured outcomes were responses to 95 questions within six sections of the survey instrument. Investigators identified two factors that significantly impacted hospital IMT decision making: (1) incident characteristics affecting a facility's internal resources and challenges; and (2) incident characteristics affecting a facility's external evacuation activities. This article summarizes the latter and reports the following critical decision making points: (1) Emergency Operations Plans (EOP) were activated an average of 85 hours (3 days, 13 hours) prior to Hurricane Rita's landfall; (2) the decision to evacuate the hospital was made an average of 30 hours (1 day, 6 hours) from activation of the EOP; and (3) the implementation of the evacuation process took an average of 22 hours. Coordination of patient evacuations was most complicated by transportation deficits (the most significant of the 11 identified problem areas) and a lack of situational awareness of community response activities. All evacuation activities and subsequent evacuation times were negatively impacted by an overall lack of understanding on the part of hospital staff and the IMT regarding how to

  13. Inelastic neutron scattering experiments with the monochromatic imaging mode of the RITA-II spectrometer

    International Nuclear Information System (INIS)

    Bahl, C.R.H.; Lefmann, K.; Abrahamsen, A.B.; Ronnow, H.M.; Saxild, F.; Jensen, T.B.S.; Udby, L.; Andersen, N.H.; Christensen, N.B.; Jakobsen, H.S.; Larsen, T.; Haefliger, P.S.; Streule, S.; Niedermayer, Ch.

    2006-01-01

    Recently a monochromatic multiple data taking mode has been demonstrated for diffraction experiments using a RITA type cold neutron spectrometer with a multi-bladed analyser and a position-sensitive detector. Here, we show how this mode can be used in combination with a flexible radial collimator to perform real inelastic neutron scattering experiments. We present the results from inelastic powder, single crystal dispersion and single crystal constant energy mapping experiments. The advantages and complications of performing these experiments are discussed along with a comparison between the imaging mode and the traditional monochromatic focussing mode

  14. Inelastic neutron scattering experiments with the monochromatic imaging mode of the RITA-II spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Bahl, C.R.H. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark) and Department of Physics, Technical University of Denmark, DK-2800 Lyngby (Denmark)]. E-mail: christian.bahl@risoe.dk; Lefmann, K. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark)]. E-mail: kim.lefmann@risoe.dk; Abrahamsen, A.B. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Ronnow, H.M. [Laboratory for Neutron Scattering, Paul Scherrer Institute, CH-5232 Villigen (Switzerland); Saxild, F. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Jensen, T.B.S. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Udby, L. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Andersen, N.H. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Christensen, N.B. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Laboratory for Neutron Scattering, Paul Scherrer Institute, CH-5232 Villigen (Switzerland); Jakobsen, H.S. [Niels Bohr Institute for Astronomy, Physics and Geophysics, University of Copenhagen, DK-2100 Copenhagen (Denmark); Larsen, T. [Niels Bohr Institute for Astronomy, Physics and Geophysics, University of Copenhagen, DK-2100 Copenhagen (Denmark); Haefliger, P.S. [Laboratory for Neutron Scattering, Paul Scherrer Institute, CH-5232 Villigen (Switzerland); Streule, S.; Niedermayer, Ch. [Laboratory for Neutron Scattering, Paul Scherrer Institute, CH-5232 Villigen (Switzerland)

    2006-05-15

    Recently a monochromatic multiple data taking mode has been demonstrated for diffraction experiments using a RITA type cold neutron spectrometer with a multi-bladed analyser and a position-sensitive detector. Here, we show how this mode can be used in combination with a flexible radial collimator to perform real inelastic neutron scattering experiments. We present the results from inelastic powder, single crystal dispersion and single crystal constant energy mapping experiments. The advantages and complications of performing these experiments are discussed along with a comparison between the imaging mode and the traditional monochromatic focussing mode.

  15. The RITA spectrometer at Risø - Design considerations and recent results

    DEFF Research Database (Denmark)

    Clausen, K.N.; McMorrow, D.F.; Lefmann, K.

    1998-01-01

    In the new cold triple axis spectrometer RITA at Riso we have improved the front end by extensive use of state of the art optical elements and better shielding material. The analyser system is situated in one large open tank and consists of seven individually orientable PC(002) crystal analyser b...... by a study of the spin fluctuations in the high T-c superconductor La1.83Sr0.17CuO4. (C) 1998 Elsevier Science B.V. All rights reserved....

  16. Metasedimentary, granitoid, and gabbroic rocks from central Stewart Island, New Zealand

    International Nuclear Information System (INIS)

    Allibone, A.H.; Tulloch, A.J.

    1997-01-01

    A NNE-NE trending strip, 3-8 km wide, extending from the Freshwater valley across Mt Rakeahua Table Hill, and Mt Allen to the northern end or the Tin Range was mapped at a scale of 1:12,500 to locate and investigate the boundary between the Median Tectonic Zone (MTZ) and Western Province on Stewart Island. A NNE-trending fault, herein termed the Escarpment Fault, separates predominantly ductily deformed rocks on its south side from essentially undeformed rocks to the north. North of the Escarpment Fault, a small (2-3 km 2 ) pluton of alkali-feldspar granite (Freds Camp) intruded gabbroic rocks tentatively considered to be associated with gabbro/anorthosite/diorite of the Rakeahua pluton, centred on Mt Rakeahua. Both units were subsequently intruded by I-type biotite granite of the South West Arm pluton. South of the Escarpment Fault the oldest intrusions are biotite tonalite-granite orthogneisses (Ridge and Table Hill plutons) intercalated with the sillimanite-cordierite-bearing Pegasus Group metasedimentary rocks, considered to represent the Western Province. They contain titanite, allanite, and magmatic epidote-bearing assemblages, implying affinities with I-type granitoids. These older granitoids have been affected by at least three phases of ductile deformation. Immediately south of the Escarpment Fault, the Escarpment pluton (hornblende, biotite, quartz, monzonite-quartz monzodiorite) only exhibit effects of the third phase of deformation. Minor gabbroic intrusives concordant with the S 3 fabric intrude the Pegasus Group and intercalated orthogneisses. Plutons of two-mica, garnet ±cordierite granite (Blaikies and Knob) and younger biotite-titanite-magmatic epidote granite (Campsite) cut fabrics associated with the third phase of ductile deformation. Preliminary U-Pb dating indicate Devonian-Carboniferous, Jurassic, and Early Cretaceous emplacement ages for Ridge Orthogneiss, Freds Camp pluton, South West Arm pluton, and Blaikies pluton, respectively. South

  17. Comparison of Conventional and ANN Models for River Flow Forecasting

    Science.gov (United States)

    Jain, A.; Ganti, R.

    2011-12-01

    Hydrological models are useful in many water resources applications such as flood control, irrigation and drainage, hydro power generation, water supply, erosion and sediment control, etc. Estimates of runoff are needed in many water resources planning, design development, operation and maintenance activities. River flow is generally estimated using time series or rainfall-runoff models. Recently, soft artificial intelligence tools such as Artificial Neural Networks (ANNs) have become popular for research purposes but have not been extensively adopted in operational hydrological forecasts. There is a strong need to develop ANN models based on real catchment data and compare them with the conventional models. In this paper, a comparative study has been carried out for river flow forecasting using the conventional and ANN models. Among the conventional models, multiple linear, and non linear regression, and time series models of auto regressive (AR) type have been developed. Feed forward neural network model structure trained using the back propagation algorithm, a gradient search method, was adopted. The daily river flow data derived from Godavari Basin @ Polavaram, Andhra Pradesh, India have been employed to develop all the models included here. Two inputs, flows at two past time steps, (Q(t-1) and Q(t-2)) were selected using partial auto correlation analysis for forecasting flow at time t, Q(t). A wide range of error statistics have been used to evaluate the performance of all the models developed in this study. It has been found that the regression and AR models performed comparably, and the ANN model performed the best amongst all the models investigated in this study. It is concluded that ANN model should be adopted in real catchments for hydrological modeling and forecasting.

  18. RITA inhibits multiple myeloma cell growth through induction of p53-mediated caspase-dependent apoptosis and synergistically enhances nutlin-induced cytotoxic responses.

    Science.gov (United States)

    Saha, Manujendra N; Jiang, Hua; Mukai, Asuka; Chang, Hong

    2010-11-01

    Mutations or deletions of p53 are relatively rare in multiple myeloma (MM), at least in newly diagnosed patients. Thus, restoration of p53 tumor suppressor function in MM by blocking the inhibitory role of murine double minute 2 (MDM2) is a promising and applicable therapeutic strategy. RITA and nutlin are two new classes of small molecule MDM2 inhibitors that prevent the p53-MDM2 interaction. Earlier reports showed p53-dependent activity of RITA in solid tumors as well as in leukemias. We and others recently described nutlin-induced apoptosis in MM cells, but it remains unclear whether RITA exerts antimyeloma activity. Here, we found that RITA activates the p53 pathway and induces apoptosis in MM cell lines and primary MM samples, preferentially killing myeloma cells. The activation of p53 induced by RITA was mediated through modulation of multiple apoptotic regulatory proteins, including upregulation of a proapoptotic protein (NOXA), downregulation of an antiapoptotic protein, Mcl-1, and activation of caspases through extrinsic pathways. Moreover, a number of key p53-mediated apoptotic target genes were identified by gene expression profiling and further validated by quantitative real-time PCR. Importantly, the combination of RITA with nutlin displayed a strong synergism on growth inhibition with the combination index ranging from 0.56 to 0.82 in MM cells. Our data support further clinical evaluation of RITA as a potential novel therapeutic intervention in MM. ©2010 AACR.

  19. Environmental Impact Report from Santa Rita Hydroelectric Power Plant (Minas Gerais State - Brazil): technical strategic for its elaboration; Relatorio de Impacto Ambiental da Usina Hidreletrica da Santa Rita (MG): estrategica tecnica para sua elaboracao

    Energy Technology Data Exchange (ETDEWEB)

    Souza, J.A. de; Marques Neto, F P [Companhia Energetica de Minas Gerais (CEMIG), Belo Horizonte, MG (Brazil)

    1990-12-31

    The steps for developing the technical strategies used on the elaboration of Environmental Impact Report from Santa Rita Hydroelectric Power Plant, Minas Gerais State, are described, including the influence area, technical requirements, impact identification, technical selection of mitigative measures, impact meaning and strategy for evaluating the identified impacts. (C.G.C.).

  20. Structure-function analysis of RBP-J-interacting and tubulin-associated (RITA) reveals regions critical for repression of Notch target genes.

    Science.gov (United States)

    Tabaja, Nassif; Yuan, Zhenyu; Oswald, Franz; Kovall, Rhett A

    2017-06-23

    The Notch pathway is a cell-to-cell signaling mechanism that is essential for tissue development and maintenance, and aberrant Notch signaling has been implicated in various cancers, congenital defects, and cardiovascular diseases. Notch signaling activates the expression of target genes, which are regulated by the transcription factor CSL (CBF1/RBP-J, Su(H), Lag-1). CSL interacts with both transcriptional corepressor and coactivator proteins, functioning as both a repressor and activator, respectively. Although Notch activation complexes are relatively well understood at the structural level, less is known about how CSL interacts with corepressors. Recently, a new RBP-J (mammalian CSL ortholog)-interacting protein termed RITA has been identified and shown to export RBP-J out of the nucleus, thereby leading to the down-regulation of Notch target gene expression. However, the molecular details of RBP-J/RITA interactions are unclear. Here, using a combination of biochemical/cellular, structural, and biophysical techniques, we demonstrate that endogenous RBP-J and RITA proteins interact in cells, map the binding regions necessary for RBP-J·RITA complex formation, and determine the X-ray structure of the RBP-J·RITA complex bound to DNA. To validate the structure and glean more insights into function, we tested structure-based RBP-J and RITA mutants with biochemical/cellular assays and isothermal titration calorimetry. Whereas our structural and biophysical studies demonstrate that RITA binds RBP-J similarly to the RAM (RBP-J-associated molecule) domain of Notch, our biochemical and cellular assays suggest that RITA interacts with additional regions in RBP-J. Taken together, these results provide molecular insights into the mechanism of RITA-mediated regulation of Notch signaling, contributing to our understanding of how CSL functions as a transcriptional repressor of Notch target genes. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

  1. saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription.

    Science.gov (United States)

    Portnoy, Victoria; Lin, Szu Hua Sharon; Li, Kathy H; Burlingame, Alma; Hu, Zheng-Hui; Li, Hao; Li, Long-Cheng

    2016-03-01

    Small activating RNAs (saRNAs) targeting specific promoter regions are able to stimulate gene expression at the transcriptional level, a phenomenon known as RNA activation (RNAa). It is known that RNAa depends on Ago2 and is associated with epigenetic changes at the target promoters. However, the precise molecular mechanism of RNAa remains elusive. Using human CDKN1A (p21) as a model gene, we characterized the molecular nature of RNAa. We show that saRNAs guide Ago2 to and associate with target promoters. saRNA-loaded Ago2 facilitates the assembly of an RNA-induced transcriptional activation (RITA) complex, which, in addition to saRNA-Ago2 complex, includes RHA and CTR9, the latter being a component of the PAF1 complex. RITA interacts with RNA polymerase II to stimulate transcription initiation and productive elongation, accompanied by monoubiquitination of histone 2B. Our results establish the existence of a cellular RNA-guided genome-targeting and transcriptional activation mechanism and provide important new mechanistic insights into the RNAa process.

  2. Secondary eyewall formation in WRF simulations of Hurricanes Rita and Katrina (2005)

    Science.gov (United States)

    Abarca, Sergio F.; Corbosiero, Kristen L.

    2011-04-01

    An analysis is presented of two high-resolution hurricane simulations of Katrina and Rita (2005) that exhibited secondary eyewall formation (SEF). The results support the notion of vortex Rossby waves (VRWs) having an important role in SEF and suggest that VRW activity is a defining aspect of the moat. SEF occurs at a radius of ˜65 (80) km in Katrina (Rita), close to the hypothesized stagnation radius of VRWs. VRW activity appears to be the result of eye-eyewall mixing events, themselves a product of the release of barotropic instability. The convection in the radial region that becomes the moat is mainly in the form of VRWs propagating radially outward from the primary eyewall until the negative radial gradient of potential vorticity is no longer conducive for their propagation. These convectively coupled waves, originating and being expelled from the eyewall, are rotation dominated and have the coherency necessary to survive their passage through the strain-dominated region outside the eyewall.

  3. From the incident command center oil spills from Hurricanes Katrina and Rita

    Energy Technology Data Exchange (ETDEWEB)

    Guidry, R.J. [Lousiana Oil Spill Coordinator' s Office, Baton Rouge, LA (United States)

    2006-07-01

    Approximately 30.2 million litres of oil were discharged during Hurricanes Katrina and Rita. A total of 230 incidents were reported to the state's spill response community, including ruptured pipelines, damaged and moved storage tanks, refineries, and sunken vessels. By January 2006, industry had reported the recovery of 14.7 million litres of oil. After Hurricane Rita, a further 234 off- and onshore incidents were reported. This paper presented a chronology from August 26 2005 through to June 2006 of clean-up activities for both hurricanes, with specific reference to logistic and communications issues associated with working in environments that are difficult to access due to damaged transportation infrastructure. An outline of the Louisiana Oil Spill Coordinator's Office's role in the incidents was presented, as well as an overview of the Louisiana State Contingency Plan. It was noted that the lack of communications systems caused considerable difficulties for responders. It was concluded that responses to hurricanes can be made more effective by having all response communities incident command structure (ICS)-trained with a thorough knowledge of the National Response Plan as it relates to the National Contingency Plan. Ensuring that plans are operational, having clear lines of authority on all hurricane-related issues, and having a robust communications plan were recommended, as well as the ability to respond without communications.

  4. The RITA spectrometer at Risø - design considerations and recent results

    Science.gov (United States)

    Clausen, K. N.; McMorrow, D. F.; Lefmann, K.; Aeppli, G.; Mason, T. E.; Schröder, A.; Issikii, M.; Nohara, M.; Takagi, H.

    In the new cold triple axis spectrometer RITA at Risø we have improved the front end by extensive use of state of the art optical elements and better shielding material. The analyser system is situated in one large open tank and consists of seven individually orientable PG(002) crystal analyser blades, and a 170 mm by 120 mm 2 areas sensitive micro-strip detector. In comparison to the old TAS6 spectrometer we have obtained a factor 2-5 gain in intensity on the sample, a substantially lower background, much more flexibility for optimising the instrument and the possibility to go beyond simple point-by-point inspection. The excellent performance of RITA in the standard TAS mode is exemplified by a study of the dynamics of ≈ 15 nm hematite (α-Fe 2O 3) nano-particles, and utilisation of horizontal and vertical focusing modes to study two dimensional systems is illustrated by a study of the spin fluctuations in the high Tc superconductor La 1.83Sr 0.17CuO 4.

  5. From the incident command center oil spills from Hurricanes Katrina and Rita

    International Nuclear Information System (INIS)

    Guidry, R.J.

    2006-01-01

    Approximately 30.2 million litres of oil were discharged during Hurricanes Katrina and Rita. A total of 230 incidents were reported to the state's spill response community, including ruptured pipelines, damaged and moved storage tanks, refineries, and sunken vessels. By January 2006, industry had reported the recovery of 14.7 million litres of oil. After Hurricane Rita, a further 234 off- and onshore incidents were reported. This paper presented a chronology from August 26 2005 through to June 2006 of clean-up activities for both hurricanes, with specific reference to logistic and communications issues associated with working in environments that are difficult to access due to damaged transportation infrastructure. An outline of the Louisiana Oil Spill Coordinator's Office's role in the incidents was presented, as well as an overview of the Louisiana State Contingency Plan. It was noted that the lack of communications systems caused considerable difficulties for responders. It was concluded that responses to hurricanes can be made more effective by having all response communities incident command structure (ICS)-trained with a thorough knowledge of the National Response Plan as it relates to the National Contingency Plan. Ensuring that plans are operational, having clear lines of authority on all hurricane-related issues, and having a robust communications plan were recommended, as well as the ability to respond without communications

  6. Mental Health, Substance Use, and Adaptive Coping among Social Work Students in the Aftermath of Hurricanes Katrina and Rita

    Science.gov (United States)

    Lemieux, Catherine M.; Plummer, Carol A.; Richardson, Roslyn; Simon, Cassandra E.; Ai, Amy L.

    2010-01-01

    The current study examined mental health symptomology, substance use, and adaptive coping among 416 social work students following Hurricanes Katrina and Rita. Among participants, 47% scored at or above the clinical level for depression, with 6% of students showing clinical PTSD-like symptoms, and 16.9% reporting substance use. Two thirds (66.9%)…

  7. Meie seast on lahkunud saksa keele tõlk Rita Tasa : [3.12.1930-16.07.2007

    Index Scriptorium Estoniae

    2007-01-01

    Järelhüüe kirjandusteadlasele, Tartu Ülikooli saksa kirjanduse õppejõule, Tallinna Pedagoogilise Instituudi saksa ja maailmakirjanduse õppejõule, saksa keele kadeedri juhatajale, saksa, šveitsi ning austria kirjanduse tõlkijale Rita Tasale

  8. Environmental Impact Report from Santa Rita Hydroelectric Power Plant (Minas Gerais State - Brazil): technical strategic for its elaboration

    International Nuclear Information System (INIS)

    Souza, J.A. de; Marques Neto, F.P.

    1989-01-01

    The steps for developing the technical strategies used on the elaboration of Environmental Impact Report from Santa Rita Hydroelectric Power Plant, Minas Gerais State, are described, including the influence area, technical requirements, impact identification, technical selection of mitigative measures, impact meaning and strategy for evaluating the identified impacts. (C.G.C.)

  9. Rescue of p53 function by small-molecule RITA in cervical carcinoma by blocking E6-mediated degradation.

    Science.gov (United States)

    Zhao, Carolyn Ying; Szekely, Laszlo; Bao, Wenjie; Selivanova, Galina

    2010-04-15

    Proteasomal degradation of p53 by human papilloma virus (HPV) E6 oncoprotein plays a pivotal role in the survival of cervical carcinoma cells. Abrogation of HPV-E6-dependent p53 destruction can therefore be a good strategy to combat cervical carcinomas. Here, we show that a small-molecule reactivation of p53 and induction of tumor cell apoptosis (RITA) is able to induce the accumulation of p53 and rescue its tumor suppressor function in cells containing high-risk HPV16 and HPV18 by inhibiting HPV-E6-mediated proteasomal degradation. RITA blocks p53 ubiquitination by preventing p53 interaction with E6-associated protein, required for HPV-E6-mediated degradation. RITA activates the transcription of proapoptotic p53 targets Noxa, PUMA, and BAX, and repressed the expression of pro-proliferative factors CyclinB1, CDC2, and CDC25C, resulting in p53-dependent apoptosis and cell cycle arrest. Importantly, RITA showed substantial suppression of cervical carcinoma xenografts in vivo. These results provide a proof of principle for the treatment of cervical cancer in a p53-dependent manner by using small molecules that target p53. (c)2010 AACR.

  10. Traumatic Loss and Natural Disaster: A Case Study of a School-Based Response to Hurricanes Katrina and Rita

    Science.gov (United States)

    Clettenberg, Stacey; Gentry, Judy; Held, Matthew; Mock, Lou Ann

    2011-01-01

    This article tracks the trajectory and impact of Hurricanes Katrina and Rita on the communities of Houston/Harris County, Texas, USA, the schools, children, and families; along with the community partnerships that addressed the trauma and upheaval. Following the influx of individuals and families who were displaced by Hurricanes Katrina and Rita…

  11. Positive Traits versus Previous Trauma: Racially Different Correlates with PTSD Symptoms among Hurricane Katrina-Rita Volunteers

    Science.gov (United States)

    Ai, Amy L.; Plummer, Carol; Kanno, Hanae; Heo, Grace; Appel, Hoa B.; Simon, Cassandra E.; Spigner, Clarence

    2011-01-01

    This study compared risks and protective factors for acquiring symptoms of posttraumatic stress disorder (PTSD) between African-American (n = 299) and European-American (n = 206) student volunteers 3 months after Hurricanes Katrina and Rita (H-KR). Respondents retrospectively provided information on peritraumatic emotional reactions and previous…

  12. Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer

    Directory of Open Access Journals (Sweden)

    Espinoza-Fonseca L Michel

    2005-09-01

    Full Text Available Abstract Background The use of low-molecular-weight, non-peptidic molecules that disrupt the interaction between the p53 tumor suppressor and its negative regulator MDM2 has provided a promising alternative for the treatment of different types of cancer. Among these compounds, RITA (reactivation of p53 and induction of tumor cell apoptosis has been shown to be effective in the selective induction of apoptosis, and this effect is due to its binding to the p53 tumor suppressor. Since biological systems are highly dynamic and MDM2 may bind to different regions of p53, new alternatives should be explored. On this basis, the computational "blind docking" approach was employed in this study to see whether RITA would bind to MDM2. Results It was observed that RITA binds to the MDM2 p53 transactivation domain-binding cleft. Thus, RITA can be used as a lead compound for designing improved "multi-target" drugs. This novel strategy could provide enormous benefits to enable effective anti-cancer strategies. Conclusion This study has demonstrated that a single molecule can target at least two different proteins related to the same disease.

  13. Rising Above the Water: New Orleans Implements Energy Efficiency and Sustainability Practices Following Hurricanes Katrina and Rita (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2012-07-01

    This fact sheet describes the technical assistance that the U.S. Department of Energy, through its National Renewable Energy Laboratory, provided to New Orleans, Louisiana, which helped the city incorporate energy efficiency into its rebuilding efforts for K-12 schools and homes following Hurricanes Katrina and Rita. NREL also provided support and analysis on energy policy efforts.

  14. RITA can induce cell death in p53-defective cells independently of p53 function via activation of JNK/SAPK and p38.

    Science.gov (United States)

    Weilbacher, A; Gutekunst, M; Oren, M; Aulitzky, W E; van der Kuip, H

    2014-07-10

    Significant advances have been made in the development of small molecules blocking the p53/MDM2 interaction. The Mdm2 inhibitor Nutlin-3 is restricted to tumors carrying wtp53. In contrast, RITA, a compound that binds p53, has recently been shown also to restore transcriptional functions of mtp53. As more than 50% of solid tumors carry p53 mutations, RITA promises to be a more effective therapeutic strategy than Nutlin-3. We investigated effects of RITA on apoptosis, cell cycle and induction of 45 p53 target genes in a panel of 14 cell lines from different tumor entities with different p53 status as well as primary lymphocytes and fibroblasts. Nine cell strains expressed wtp53, four harbored mtp53, and three were characterized by the loss of p53 protein. A significant induction of cell death upon RITA was observed in 7 of 16 cell lines. The nonmalignant cells in our panel were substantially less sensitive. We found that in contrast to Nultin-3, RITA is capable to induce cell death not only in tumor cells harboring wtp53 and mtp53 but also in p53-null cells. Importantly, whereas p53 has a central role for RITA-mediated effects in wtp53 cells, neither p53 nor p63 or p73 were essential for the RITA response in mtp53 or p53-null cells in our panel demonstrating that besides the known p53-dependent action of RITA in wtp53 cells, RITA can induce cell death also independently of p53 in cells harboring defective p53. We identified an important role of both p38 and JNK/SAPK for sensitivity to RITA in these cells leading to a typical caspase- and BAX/BAK-dependent mitochondrial apoptosis. In conclusion, our data demonstrate that RITA can induce apoptosis through p38 and JNK/SAPK not only in tumor cells harboring wtp53 and mtp53 but also in p53-null cells, making RITA an interesting tumor-selective drug.

  15. Anne Frank relaunched in the world of comics and graphic novels

    NARCIS (Netherlands)

    Ribbens, Kees

    2017-01-01

    Recently the Basel-based Anne Frank Fonds proudly presented the Graphic Diary of Anne Frank. The impression is created as if this is the first ever comic book version of Anne Frank’s narrative. This article shows that there were various predecessors.

  16. A randomized comparison of the Saphenous Vein Versus Right Internal Thoracic Artery as a Y-Composite Graft (SAVE RITA) trial: One-year angiographic results and mid-term clinical outcomes.

    Science.gov (United States)

    Kim, Ki-Bong; Hwang, Ho Young; Hahn, Seokyung; Kim, Jun Sung; Oh, Se Jin

    2014-09-01

    The Saphenous Vein Versus Right Internal Thoracic Artery as a Y-Composite Graft (SAVE RITA) trial was designed to evaluate the noninferiority of the saphenous vein (SV) compared with the right internal thoracic artery ([R]ITA) used as a Y-composite graft. A total of 224 patients who had undergone off-pump revascularization for multivessel coronary artery disease using the SV or RITA as a Y-composite graft based on the in situ left ITA were assigned randomly to the SV Y-composite graft (SV group, n = 112) or free RITA Y-composite graft (RITA group, n = 112). The primary endpoint was the 1-year angiographic patency rate of the second limb conduits (SV or RITA). Postoperative 1-year coronary angiograms were performed in 215 patients (SV group, 108; RITA group, 107). The overall graft patency rate was 97.4% (745 of 765) at 1 year (97.9% in the SV group vs 96.9% in the RITA group, P = .362). The primary endpoint of the study, the 1-year patency rate of the SV composite grafts, was 97.1% (238 of 245) and was noninferior to that of the RITA composite grafts (97.1% [198 of 204]) with a 95% lower confidence limit of -2.6% (P RITA composite grafts in terms of the 1-year angiographic patency rates. Copyright © 2014 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

  17. p53-dependent inhibition of TrxR1 contributes to the tumor-specific induction of apoptosis by RITA.

    Science.gov (United States)

    Hedström, Elisabeth; Eriksson, Sofi; Zawacka-Pankau, Joanna; Arnér, Elias S J; Selivanova, Galina

    2009-11-01

    Thioredoxin reductase 1 (TrxR1) is a key regulator in many redox-dependent cellular pathways, and is often overexpressed in cancer. Several studies have identified TrxR1 as a potentially important target for anticancer therapy. The low molecular weight compound RITA (NSC 652287) binds p53 and induces p53-dependent apoptosis. Here we found that RITA also targets TrxR1 by non-covalent binding, followed by inhibition of its activity in vitro and by inhibition of TrxR activity in cancer cells. Interestingly, a novel approximately 130 kDa form of TrxR1, presumably representing a stable covalently linked dimer, and an increased generation of reactive oxygen species (ROS) were induced by RITA in cancer cells in a p53-dependent manner. Similarly, the gold-based TrxR inhibitor auranofin induced apoptosis related to oxidative stress, but independently of p53 and without apparent induction of the approximately 130 kDa form of TrxR1. In contrast to the effects observed in cancer cells, RITA did not inhibit TrxR or ROS formation in normal fibroblasts (NHDF). The inhibition of TrxR1 can sensitize tumor cells to agents that induce oxidative stress and may directly trigger cell death. Thus, our results suggest that a unique p53-dependent effect of RITA on TrxR1 in cancer cells might synergize with p53-dependent induction of pro-apoptotic genes and oxidative stress, thereby leading to a robust induction of cancer cell death, without affecting non-transformed cells.

  18. Jo Ann Baumgartner and Sam Earnshaw: Organizers and Farmers

    OpenAIRE

    Rabkin, Sarah

    2010-01-01

    Jo Ann Baumgartner directs the Wild Farm Alliance, based in Watsonville, California. WFA’s mission, as described on the organization’s website, is “to promote agriculture that helps to protect and restore wild Nature.” Through research, publications, presentations, events, policy work, and consulting, the organization works to “connect food systems with ecosystems.” Sam Earnshaw is Central Coast regional coordinator of the Community Alliance with Family Farmers. Working with CAFF’s f...

  19. Comparison of ANN and RKS approaches to model SCC strength

    Science.gov (United States)

    Prakash, Aravind J.; Sathyan, Dhanya; Anand, K. B.; Aravind, N. R.

    2018-02-01

    Self compacting concrete (SCC) is a high performance concrete that has high flowability and can be used in heavily reinforced concrete members with minimal compaction segregation and bleeding. The mix proportioning of SCC is highly complex and large number of trials are required to get the mix with the desired properties resulting in the wastage of materials and time. The research on SCC has been highly empirical and no theoretical relationships have been developed between the mixture proportioning and engineering properties of SCC. In this work effectiveness of artificial neural network (ANN) and random kitchen sink algorithm(RKS) with regularized least square algorithm(RLS) in predicting the split tensile strength of the SCC is analysed. Random kitchen sink algorithm is used for mapping data to higher dimension and classification of this data is done using Regularized least square algorithm. The training and testing data for the algorithm was obtained experimentally using standard test procedures and materials available. Total of 40 trials were done which were used as the training and testing data. Trials were performed by varying the amount of fine aggregate, coarse aggregate, dosage and type of super plasticizer and water. Prediction accuracy of the ANN and RKS model is checked by comparing the RMSE value of both ANN and RKS. Analysis shows that eventhough the RKS model is good for large data set, its prediction accuracy is as good as conventional prediction method like ANN so the split tensile strength model developed by RKS can be used in industries for the proportioning of SCC with tailor made property.

  20. Intelligent MRTD testing for thermal imaging system using ANN

    Science.gov (United States)

    Sun, Junyue; Ma, Dongmei

    2006-01-01

    The Minimum Resolvable Temperature Difference (MRTD) is the most widely accepted figure for describing the performance of a thermal imaging system. Many models have been proposed to predict it. The MRTD testing is a psychophysical task, for which biases are unavoidable. It requires laboratory conditions such as normal air condition and a constant temperature. It also needs expensive measuring equipments and takes a considerable period of time. Especially when measuring imagers of the same type, the test is time consuming. So an automated and intelligent measurement method should be discussed. This paper adopts the concept of automated MRTD testing using boundary contour system and fuzzy ARTMAP, but uses different methods. It describes an Automated MRTD Testing procedure basing on Back-Propagation Network. Firstly, we use frame grabber to capture the 4-bar target image data. Then according to image gray scale, we segment the image to get 4-bar place and extract feature vector representing the image characteristic and human detection ability. These feature sets, along with known target visibility, are used to train the ANN (Artificial Neural Networks). Actually it is a nonlinear classification (of input dimensions) of the image series using ANN. Our task is to justify if image is resolvable or uncertainty. Then the trained ANN will emulate observer performance in determining MRTD. This method can reduce the uncertainties between observers and long time dependent factors by standardization. This paper will introduce the feature extraction algorithm, demonstrate the feasibility of the whole process and give the accuracy of MRTD measurement.

  1. A Hybrid FEM-ANN Approach for Slope Instability Prediction

    Science.gov (United States)

    Verma, A. K.; Singh, T. N.; Chauhan, Nikhil Kumar; Sarkar, K.

    2016-09-01

    Assessment of slope stability is one of the most critical aspects for the life of a slope. In any slope vulnerability appraisal, Factor Of Safety (FOS) is the widely accepted index to understand, how close or far a slope from the failure. In this work, an attempt has been made to simulate a road cut slope in a landslide prone area in Rudrapryag, Uttarakhand, India which lies near Himalayan geodynamic mountain belt. A combination of Finite Element Method (FEM) and Artificial Neural Network (ANN) has been adopted to predict FOS of the slope. In ANN, a three layer, feed- forward back-propagation neural network with one input layer and one hidden layer with three neurons and one output layer has been considered and trained using datasets generated from numerical analysis of the slope and validated with new set of field slope data. Mean absolute percentage error estimated as 1.04 with coefficient of correlation between the FOS of FEM and ANN as 0.973, which indicates that the system is very vigorous and fast to predict FOS for any slope.

  2. ARSENIC REMOVAL FROM DRINKING WATER BY IRON REMOVAL AND ADSORPTIVE MEDIA USEPA DEMONSTRATION PROJECT AT STEWART, MN. SIX-MONTH EVALUATION REPORT

    Science.gov (United States)

    This report documents the activities performed and the results obtained from the first six months of the EPA arsenic removal technology demonstration project at the Stewart, MN facility. The main objective of the project is to evaluate the effectiveness of Siemens¿ Type II AERALA...

  3. Full penetrance of Morgagni-Stewart-Morel syndrome in a 75-year-old woman: case report and review of the literature.

    Science.gov (United States)

    Attanasio, Francesca; Granziera, Serena; Giantin, Valter; Manzato, Enzo

    2013-02-01

    Morgagni-Stewart-Morel syndrome is defined as the presence of hyperostosis frontalis interna, variably associated with metabolic, endocrine, and neuropsychiatric disorders. The possible cause-effect relationship of these associations remains uncertain. A 75-year-old woman presented with severe frontal headache and a history of psychotic disorders. On instrumental examination she was found to have extensive frontal hyperostosis and cortical atrophy. These findings, associated to the metabolic and neuropsychiatric pattern of the patient, are consistent with a high penetrance of Morgagni-Stewart-Morel syndrome. In this clinical case seminar, we summarize the current understanding of the association between hyperostosis frontalis interna and Morgagni-Stewart-Morel, based on a MEDLINE search (case reports, original articles, and reviews published between 1928 and 2011) on this topic. Possible pathophysiological mechanisms underlying both the headache and the hyperostosis frontalis interna are discussed. A case of full penetrance of Morgagni-Stewart-Morel syndrome is reported, presenting many of the clinical features described in the literature. Metabolic and endocrine dysfunctions should be interpreted not only as isolated components of the syndrome, but also as the reason behind its pathogenesis. Endocrine or nutritional disorders may have led to an altered bone metabolism with frontal bone apposition. On the other hand, the severity of our patient's neurological and psychiatric symptoms correlates well with the severity of her hyperostosis frontalis interna and the cortical atrophy.

  4. The first lady almoner: the appointment, position, and findings of Miss Mary Stewart at the Royal Free Hospital, 1895-99.

    Science.gov (United States)

    Cullen, Lynsey T

    2013-10-01

    This article examines the professional roots of the hospital almoner, a position which has been widely neglected in medical history. The first almoner was Miss Mary Stewart, a former Charity Organization Society employee, appointed at the Royal Free Hospital of central London in 1895. The Royal Free was a charitable hospital which offered free medical treatment to patients considered morally deserving but unable to afford medical care elsewhere. The role expected of Stewart was to means test patients in order to ensure that only those deemed "appropriate" received free medical treatment, and to establish the extent to which the hospital was being abused by those who could afford to contribute toward their medical care. While in office, Stewart continually reshaped the role of almoner. She fashioned the position into that of a medical social worker and undertook such duties as referring patients to other means of medical and charitable assistance, visiting patients' homes, and training almoners for positions at other voluntary hospitals. Through the examination of Mary Stewart's Almoners Report Book, this article considers the circumstances of her appointment, the role she performed, and the findings of her investigations.

  5. The First Lady Almoner: The Appointment, Position, and Findings of Miss Mary Stewart at the Royal Free Hospital, 1895–99

    Science.gov (United States)

    Cullen, Lynsey T.

    2013-01-01

    This article examines the professional roots of the hospital almoner, a position which has been widely neglected in medical history. The first almoner was Miss Mary Stewart, a former Charity Organization Society employee, appointed at the Royal Free Hospital of central London in 1895. The Royal Free was a charitable hospital which offered free medical treatment to patients considered morally deserving but unable to afford medical care elsewhere. The role expected of Stewart was to means test patients in order to ensure that only those deemed “appropriate” received free medical treatment, and to establish the extent to which the hospital was being abused by those who could afford to contribute toward their medical care. While in office, Stewart continually reshaped the role of almoner. She fashioned the position into that of a medical social worker and undertook such duties as referring patients to other means of medical and charitable assistance, visiting patients' homes, and training almoners for positions at other voluntary hospitals. Through the examination of Mary Stewart's Almoners Report Book, this article considers the circumstances of her appointment, the role she performed, and the findings of her investigations. PMID:22474098

  6. Arsenic Removal from Drinking Water by Iron Removal and Adsorptive Media U.S. EPA Demonstration Project at Stewart, MN, Final Performance Evaluation Report

    Science.gov (United States)

    This report documents the activities performed and the results obtained from the one-year U.S. Environmental Protection Agency (EPA) arsenic removal technology demonstration project at the Stewart, MN facility. The main objective of the project was to evaluate the effectiveness ...

  7. Luksuslik ruum kõigile : vestlus arhitekt Anne Lacatoniga = Luxury space for everyone : interview with Anne Lacaton / intervjueerinud Katrin Paadam

    Index Scriptorium Estoniae

    Lacaton, Anne, 1955-

    2013-01-01

    Prantsuse arhitekt Anne Lacaton oma büroo (Lacaton & Vassal, Frédéric Druot, 2011) linnaehituslikult uuendusliku projekti järgi ümber ehitatud 1960. aastate korterelamust Tour du Bois-le-Prêtre Pariisis, sotsiaalelamute ehitusest Prantsusmaal, 1960.-1970. aastatel ehitatud elamute taaskasutusega seotud probleemidest, rekonstrueerimise kasulikkusest võrreldes elamu lammutamise ja uuesti ehitamisega, linnas elavatele inimestele paremate elamistingimuste loomisest, linnaplaneerimisest

  8. Morphological responses of the Wax Lake Delta, Louisiana, to Hurricanes Rita

    Directory of Open Access Journals (Sweden)

    Fei Xing

    2017-12-01

    Full Text Available This study examines the morphodynamic response of a deltaic system to extreme weather events. The Wax Lake Delta (WLD in Louisiana, USA, is used to illustrate the impact of extreme events (hurricanes on a river-dominated deltaic system. Simulations using the open source Delft3D model reveal that Hurricane Rita, which made landfall 120 km to the west of WLD as a Category 3 storm in 2005, caused erosion on the right side and deposition on the left side of the hurricane eye track on the continental shelf line (water depth 10 m to 50 m. Erosion over a wide area occurred both on the continental shelf line and in coastal areas when the hurricane moved onshore, while deposition occurred along the Gulf coastline (water depth < 5 m when storm surge water moved back offshore. The numerical model estimated that Hurricane Rita’s storm surge reached 2.5 m, with maximum currents of 2.0 m s–1, and wave heights of 1.4 m on the WLD. The northwestern-directed flow and waves induced shear stresses, caused erosion on the eastern banks of the deltaic islands and deposition in channels located west of these islands. In total, Hurricane Rita eroded more than 500,000 m3 of sediments on the WLD area. Including waves in the analysis resulted in doubling the amount of erosion in the study area, comparing to the wave-excluding scenario. The exclusion of fluvial input caused minor changes in deltaic morphology during the event. Vegetation cover was represented as rigid rods in the model which add extra source terms for drag and turbulence to influence the momentum and turbulence equations. Vegetation slowed down the floodwater propagation and decreased flow velocity on the islands, leading to a 47% reduction in the total amount of erosion. Morphodynamic impact of the hurricane track relative to the delta was explored. Simulations indicate that the original track of Hurricane Rita (landfall 120 km west of the WLD produced twice as much erosion and deposition at the delta

  9. Orkaan Rita ähvardab rüüstata USA naftatööstuse südame / Annika Matson

    Index Scriptorium Estoniae

    Matson, Annika, 1976-

    2005-01-01

    Orkaan Rita läheneb USA naftatööstuse südamele Texasele, kus toodetakse veerand USA naftatoodetest. Diagramm: Naftafirmade aktsiate tõus. Vt. samas: Bensiini hinna olulist tõusu Eestis prognoosida oleks ennatlik

  10. Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu

    Directory of Open Access Journals (Sweden)

    Luan Jinwei

    2016-06-01

    Full Text Available Next generation sequencing and bio-informatic analyses were conducted to investigate the mechanism of reactivation of p53 and induction of tumor cell apoptosis (RITA-enhancing X-ray susceptibility in FaDu cells.

  11. A Class of Generalized Gough-Stewart Platforms Used for Effectively Obtaining Dynamic Isotropy – An Analytical Study

    Directory of Open Access Journals (Sweden)

    Afzali-Far Behrouz

    2015-01-01

    Full Text Available In this paper, we propose a class of Generalized Gough-Stewart Platforms (GGSPs used, as a novel approach, to eliminate the classical isotropic constraint of GSPs (hexapods. GGSPs are based on the standard GSP architecture with additional rotations of the three strut-pairs. Despite the architectural generalization introduced in GGSPs, they do not require much more effort in order to be fabricated. This is due to the fact that all the struts (actuators can be chosen identical, similar to standard GSPs. We analytically show how effectively the classical isotropic constraint is removed and that still sufficient simplicity is retained. Furthermore, this paper gives an intuitive understanding of dynamic isotropy in GGSPs as well as GSPs.

  12. RITA enhances irradiation-induced apoptosis in p53-defective cervical cancer cells via upregulation of IRE1α/XBP1 signaling.

    Science.gov (United States)

    Zhu, Hong; Abulimiti, Muyasha; Liu, Huan; Su, Xiang-Jiang; Liu, Cai-Hong; Pei, Hai-Ping

    2015-09-01

    Radiation therapy is the most widely used treatment for patients with cervical cancer. Recent studies have shown that endoplasmic reticulum (ER) stress induces apoptosis and sensitizes tumor cells to radiotherapy, which reportedly induces ER stress in cells. Classical key tumor suppressor p53 is involved in the response to a variety of cellular stresses, including those incurred by ionizing irradiation. A recent study demonstrated that small-molecule RITA (reactivation of p53 and induction of tumor cell apoptosis) increased the radiosensitivity of tumor cells expressing mutant p53 (mtp53). In the present study, we explored the effects and the underlying mechanisms of RITA in regards to the radiosensitivity and ER stress in mtp53-expressing human cervix cancer cells. Treatment with 1 µM of RITA for 24 h before irradiation markedly decreased survival and increased apoptosis in C-33A and HT-3 cells; the effects were not significantly altered by knockdown of p53. In the irradiated C-33A and HT-3 cells, RITA significantly increased the expression of IRE1α, the spliced XBP1 mRNA level, as well as apoptosis; the effects were abolished by knockdown of IRE1α. Transcriptional pulse-chase assays revealed that RITA significantly increased the stability of IRE1α mRNA in the irradiated C-33A and HT-3 cells. In contrast, the same RITA treatment did not show any significant effect on sham-irradiated cells. In conclusion, the present study provides initial evidence that RITA upregulates the expression level of IRE1α by increasing the stability of IRE1α mRNA in irradiated mtp53-expressing cervical cancer cells; the effect leads to enhanced IRE1α/XBP1 ER stress signaling and increased apoptosis in the cells. The present study offers novel insight into the pharmacological potential of RITA in the radiotherapy for cervical cancer.

  13. A Prospective Study of Religiousness and Psychological Distress Among Female Survivors of Hurricanes Katrina and Rita

    Science.gov (United States)

    Rhodes, Jean E.; Pérez, John E.

    2013-01-01

    This prospective study examined the pathways by which religious involvement affected the post-disaster psychological functioning of women who survived Hurricanes Katrina and Rita. The participants were 386 low-income, predominantly Black, single mothers. The women were enrolled in the study before the hurricane, providing a rare opportunity to document changes in mental health from before to after the storm, and to assess the protective role of religious involvement over time. Results of structural equation modeling indicated that, controlling for level of exposure to the hurricanes, pre-disaster physical health, age, and number of children, pre-disaster religiousness predicted higher levels of post-disaster (1) social resources and (2) optimism and sense of purpose. The latter, but not the former, was associated with better post-disaster psychological outcome. Mediation analysis confirmed the mediating role of optimism and sense of purpose. PMID:21626083

  14. Satellite Images and Aerial Photographs of the Effects of Hurricanes Katrina and Rita on Coastal Louisiana

    Science.gov (United States)

    Barras, John A.

    2007-01-01

    Introduction Hurricane Katrina made landfall on the eastern coastline of Louisiana on August 29, 2005; Hurricane Rita made landfall on the western coastline of Louisiana on September 24, 2005. Comparison of Landsat Thematic Mapper (TM) satellite imagery acquired before and after the landfalls of Katrina and Rita and classified to identify land and water demonstrated that water area increased by 217 mi2 (562 km2) in coastal Louisiana as a result of the storms. Approximately 82 mi2 (212 km2) of new water areas were in areas primarily impacted by Hurricane Katrina (Mississippi River Delta basin, Breton Sound basin, Pontchartrain basin, and Pearl River basin), whereas 99 mi2 (256 km2) were in areas primarily impacted by Hurricane Rita (Calcasieu/Sabine basin, Mermentau basin, Teche/Vermilion basin, Atchafalaya basin, and Terrebonne basin). Barataria basin contained new water areas caused by both hurricanes, resulting in some 18 mi2 (46.6 km2) of new water areas. The fresh marsh and intermediate marsh communities' land areas decreased by 122 mi2 (316 km2) and 90 mi2 (233.1 km2), respectively, and the brackish marsh and saline marsh communities' land areas decreased by 33 mi2 (85.5 km2) and 28 mi2 (72.5 km2), respectively. These new water areas represent land losses caused by direct removal of wetlands. They also indicate transitory changes in water area caused by remnant flooding, removal of aquatic vegetation, scouring of marsh vegetation, and water-level variation attributed to normal tidal and meteorological variation between satellite images. Permanent losses cannot be estimated until several growing seasons have passed and the transitory impacts of the hurricanes are minimized. The purpose of this study was to provide preliminary information on water area changes in coastal Louisiana acquired shortly after the landfalls of both hurricanes (detectable with Landsat TM imagery) and to serve as a regional baseline for monitoring posthurricane wetland recovery. The land

  15. The monochromatic imaging mode of a RITA-type neutron spectrometer

    International Nuclear Information System (INIS)

    Bahl, C.R.H.; Andersen, P.; Klausen, S.N.; Lefmann, K.

    2004-01-01

    The imaging monochromatic mode of a neutron spectrometer with a multi-bladed RITA analyser system is so far unexplored. We present analytical calculations that define the mode. It is shown that the mode can be realised for PG (0 0 2) analyser crystals, from incident energies of about 3.2 meV and up, allowing the important cases of 3.7, 5.0 and 13.7 meV. Due to beam divergence, the neutron rays from neighbouring analyser blades are found to overlap slightly. Hence, the optimal use of the monochromatic imaging mode would be found by employing an adjustable radial collimator to limit the spread of the ray from each analyser blade

  16. Bacteriological water quality in the Lake Pontchartrain basin Louisiana following Hurricanes Katrina and Rita, September 2005

    Science.gov (United States)

    Stoeckel, Donald M.; Bushon, Rebecca N.; Demcheck, Dennis K.; Skrobialowski, Stanley C.; Kephart, Christopher M.; Bertke, Erin E.; Mailot, Brian E.; Mize, Scott V.; Fendick, Robert B.

    2005-01-01

    The U.S. Geological Survey (USGS), in collaboration with the Louisiana Department of Environmental Quality, monitored bacteriological quality of water at 22 sites in and around Lake Pontchartrain, La., for three consecutive weeks beginning September 13, 2005, following hurricanes Katrina and Rita and the associated flooding. Samples were collected and analyzed by USGS personnel from the USGS Louisiana Water Science Center and the USGS Ohio Water Microbiology Laboratory. Fecal-indicator bacteria (Escherichia coli, enterococci, and fecal coliform) concentrations ranged from the detection limit to 36,000 colony-forming units per 100 milliliters. Data are presented in tabular form and as plots of data in the context of available historical data and water-quality standards and criteria for each site sampled. Quality-control data were reviewed to ensure that methods performed as expected in a mobile laboratory setting.

  17. A prospective study of religiousness and psychological distress among female survivors of Hurricanes Katrina and Rita.

    Science.gov (United States)

    Chan, Christian S; Rhodes, Jean E; Pérez, John E

    2012-03-01

    This prospective study examined the pathways by which religious involvement affected the post-disaster psychological functioning of women who survived Hurricanes Katrina and Rita. The participants were 386 low-income, predominantly Black, single mothers. The women were enrolled in the study before the hurricane, providing a rare opportunity to document changes in mental health from before to after the storm, and to assess the protective role of religious involvement over time. Results of structural equation modeling indicated that, controlling for level of exposure to the hurricanes, pre-disaster physical health, age, and number of children, pre-disaster religiousness predicted higher levels of post-disaster (1) social resources and (2) optimism and sense of purpose. The latter, but not the former, was associated with better post-disaster psychological outcome. Mediation analysis confirmed the mediating role of optimism and sense of purpose.

  18. Rita Temmerman. Towards New Ways of Terminology Description: The Sociocognitive Approach

    Directory of Open Access Journals (Sweden)

    Rosemarie Gläser

    2011-10-01

    Full Text Available This book appeared as Volume 3 in the Series Terminology and Lexicography Research and Practice edited by Helmi Sonneveld and Sue-Ellen Wright. The author, Rita Temmerman, presently working at the Erasmus Hogeschool, Brussels and specialising in problems of terminology in various domains of the life sciences, presents a polemical, stimulating and innovative monograph which continues and deepens her previous research work. Her doctoral dissertation (Louvain 1998 focused on Terminology Beyond Standardisation: Language and Categorisation in the Life Sciences. The aim of the book under review, Towards New Ways of Terminology Description: The Sociocognitive Approach, is to elaborate a new theory, method and application of terminology research which seeks to overcome the obvious limitations of traditional terminology as chiefly represented by the Vienna School (Eugen W?ster, Helmut Felber, Infoterm and associated institutions.

  19. Rezension zu: Rita Pawlowski (Hg.: „Unsere Frauen stehen ihren Mann“. Berlin: trafo Wissenschaftsverlag 2008

    Directory of Open Access Journals (Sweden)

    Susanne Freund

    2009-07-01

    Full Text Available Rita Pawlowski stellt in diesem Band in alphabethischer Ordnung insgesamt 651 Frauen vor, die Abgeordnete der Volkskammer der DDR waren. Nach einer knappen Einführung zur Wahlhäufigkeit weiblicher Abgeordneter, zum Frauenanteil in der Volkskammer und in den Ausschüssen geben die Biographen im Wesentlichen Auskunft über die soziale Herkunft, die Parteizugehörigkeit, die schulische und berufliche Ausbildung und die Berufstätigkeit der einzelnen Frauen. Ziel dieses Bandes ist die Dokumentation des außergewöhnlichen Engagements von Frauen in der DDR, neben Berufstätigkeit und Familienpflichten politische Einflussmöglichkeiten zu nutzen. Damit wird ein Teilaspekt der Lebensgeschichte dieser Frauen beleuchtet, der – wie die Autorin im Vorfeld einräumt – keinen Anspruch auf Vollständigkeit erhebt. Dieser Hinweis ist wichtig, um dieses lexikalische Nachschlagewerk sinnvoll zu handhaben.

  20. The monochromatic imaging mode of a RITA-type neutron spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Bahl, C.R.H. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark) and Department of Physics, Technical University of Denmark, DK-2800 Lyngby (Denmark)]. E-mail: christian.bahl@risoe.dk; Andersen, P. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Niels Bohr Institute for Astronomy, Physics and Geophysics, University of Copenhagen, DK-2100 Copenhagen (Denmark); Klausen, S.N. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark); Lefmann, K. [Department of Materials Research, Riso National Laboratory, Building 227, Frederiksborgvej 399, DK-4000 Roskilde (Denmark)

    2004-12-01

    The imaging monochromatic mode of a neutron spectrometer with a multi-bladed RITA analyser system is so far unexplored. We present analytical calculations that define the mode. It is shown that the mode can be realised for PG (0 0 2) analyser crystals, from incident energies of about 3.2 meV and up, allowing the important cases of 3.7, 5.0 and 13.7 meV. Due to beam divergence, the neutron rays from neighbouring analyser blades are found to overlap slightly. Hence, the optimal use of the monochromatic imaging mode would be found by employing an adjustable radial collimator to limit the spread of the ray from each analyser blade.

  1. Efficient synthesis of RITA and its analogues: derivation of analogues with improved antiproliferative activity via modulation of p53/miR-34a pathway.

    Science.gov (United States)

    Lin, Jinshun; Jin, Xiuli; Bu, Yiwen; Cao, Deliang; Zhang, Nannan; Li, Shangfu; Sun, Qinsheng; Tan, Chunyan; Gao, Chunmei; Jiang, Yuyang

    2012-12-28

    A novel approach to synthesize RITA by practical palladium-catalyzed C-C bond-forming Suzuki reactions at room temperature was developed, which was used for deriving a series of substituted tricyclic α-heteroaryl (furan/thiophene) analogues of RITA under mild conditions. These novel analogues showed notable antiproliferative activity against cancer cell lines with wild-type p53 (i.e., HCT116, A549, MCF-7 and K562), but much less activity in HCT116/p53(-/-) cells. In particular, compound 1f demonstrated promising antiproliferative activity compared to RITA, with IC(50) = 28 nM in MCF-7 vs. 54 nM for RITA, and cancer cell selectivity. Compound 1f markedly activated p53 in HCT116 cells at 100 nM, triggering apoptosis. Importantly, we found that both RITA and compound 1f induced G(0)/G(1) cell cycle arrest by up-regulating miR-34a, which in turn down-regulated the expression of cell cycle-related proteins CDK4 and E2F1. In summary, this study reports an effective synthetic approach for RITA and its analogues, and elucidates a novel antiproliferative mechanism of these compounds.

  2. Initial management of hospital evacuations caused by Hurricane Rita: a systematic investigation.

    Science.gov (United States)

    Downey, Erin L; Andress, Knox; Schultz, Carl H

    2013-06-01

    Hurricanes remain a major threat to hospitals throughout the world. The authors attempted to identify the planning areas that impact hospital management of evacuations and the challenges faced when sheltering-in-place. This observational, retrospective cohort study examined acute care institutions from one hospital system impacted by Hurricane Rita in 2005. Investigators used a standardized survey instrument and interview process, previously used in the hospital evacuation context, to examine hospitals' initial internal situational awareness and subsequent decision making that resulted in evacuation due to Hurricane Rita. Participants from each hospital included representatives from senior leadership and clinical and nonclinical staff that comprised the Incident Management Team (IMT). The main measured outcomes were responses to 95 questions contained in the survey. Seven of ten eligible hospitals participated in the study. All facilities evacuated the sickest patients first. The most significant factors prompting evacuation were the issuing of mandatory evacuation orders, storm dynamics (category, projected path, storm surge), and loss of regional communications. Hospitals that sheltered-in-place experienced staff shortages, interruptions to electrical power, and loss of water supplies. Three fully-evacuated institutions experienced understaffing of 40%-60%, and four hospitals sustained depressed staffing levels for over four weeks. Five hospitals lost electricity for a mean of 4.8 days (range .5-11 days). All facilities continued to receive patients to their Emergency Departments (EDs) while conducting their own evacuation. Hospital EDs should plan for continuous patient arrival during evacuation. Emergency Operation Plans (EOPs) that anticipate challenges associated with evacuation will help to maximize initial decision making and management during a crisis situation. Hospitals that shelter-in-place face critical shortages and must provide independent patient

  3. Mapping and Visualization of Storm-Surge Dynamics for Hurricane Katrina and Hurricane Rita

    Science.gov (United States)

    Gesch, Dean B.

    2009-01-01

    The damages caused by the storm surges from Hurricane Katrina and Hurricane Rita were significant and occurred over broad areas. Storm-surge maps are among the most useful geospatial datasets for hurricane recovery, impact assessments, and mitigation planning for future storms. Surveyed high-water marks were used to generate a maximum storm-surge surface for Hurricane Katrina extending from eastern Louisiana to Mobile Bay, Alabama. The interpolated surface was intersected with high-resolution lidar elevation data covering the study area to produce a highly detailed digital storm-surge inundation map. The storm-surge dataset and related data are available for display and query in a Web-based viewer application. A unique water-level dataset from a network of portable pressure sensors deployed in the days just prior to Hurricane Rita's landfall captured the hurricane's storm surge. The recorded sensor data provided water-level measurements with a very high temporal resolution at surveyed point locations. The resulting dataset was used to generate a time series of storm-surge surfaces that documents the surge dynamics in a new, spatially explicit way. The temporal information contained in the multiple storm-surge surfaces can be visualized in a number of ways to portray how the surge interacted with and was affected by land surface features. Spatially explicit storm-surge products can be useful for a variety of hurricane impact assessments, especially studies of wetland and land changes where knowledge of the extent and magnitude of storm-surge flooding is critical.

  4. The burden of rare cancers in Italy: the surveillance of rare cancers in Italy (RITA) project.

    Science.gov (United States)

    Trama, Annalisa; Mallone, Sandra; Ferretti, Stefano; Meduri, Francesca; Capocaccia, Riccardo; Gatta, Gemma

    2012-01-01

    The project Surveillance of rare cancers in Italy (RITA) provides, for the first time, estimates of the burden of rare cancers in Italy based on the list of rare cancers proposed in collaboration with the European project Surveillance of Rare Cancers in Europe (RARECARE). RITA analyzed data from Italian population-based cancer registries (CR). The period of diagnosis was 1988 to 2002, and vital status information was available up to December 31, 2003. Incidence rates were estimated for the period 1995-2002, survival for the years 2000-2002 (with the period method of Brenner), and complete prevalence at January 1, 2003. Rare cancers are those with an incidence <6/100,000/year. In Italy, every year there are 60,000 new diagnoses of rare cancers corresponding to 15% of all new cancer diagnoses. Five-year relative survival was on the average worse for rare cancers (53%) than for common cancers (73%). A total of 770,000 patients were living in Italy in 2008 with a diagnosis of a rare cancer, 22% of the total cancer prevalence. Our estimates constitute a useful base for further research and support the idea that rare cancers are a public health problem that deserves attention. Centers of expertise for rare cancers that pool cases, expertise and resources could ensure an adequate clinical management for these diseases. Our data also showed that cancer registries are suitable sources of data to estimate incidence, prevalence and survival for rare cancers and should continue to monitoring rare cancers in Italy.

  5. Rita Pawlowski (Hg.: „Unsere Frauen stehen ihren Mann“. Berlin: trafo Wissenschaftsverlag 2008

    Directory of Open Access Journals (Sweden)

    Susanne Freund

    2009-07-01

    Full Text Available Rita Pawlowski stellt in diesem Band in alphabethischer Ordnung insgesamt 651 Frauen vor, die Abgeordnete der Volkskammer der DDR waren. Nach einer knappen Einführung zur Wahlhäufigkeit weiblicher Abgeordneter, zum Frauenanteil in der Volkskammer und in den Ausschüssen geben die Biographen im Wesentlichen Auskunft über die soziale Herkunft, die Parteizugehörigkeit, die schulische und berufliche Ausbildung und die Berufstätigkeit der einzelnen Frauen. Ziel dieses Bandes ist die Dokumentation des außergewöhnlichen Engagements von Frauen in der DDR, neben Berufstätigkeit und Familienpflichten politische Einflussmöglichkeiten zu nutzen. Damit wird ein Teilaspekt der Lebensgeschichte dieser Frauen beleuchtet, der – wie die Autorin im Vorfeld einräumt – keinen Anspruch auf Vollständigkeit erhebt. Dieser Hinweis ist wichtig, um dieses lexikalische Nachschlagewerk sinnvoll zu handhaben.In this volume, Rita Pawlowski alphabetically introduces a total of 651 women who were representatives of the People’s Chamber of the GDR. Following a short introduction to the election frequency of female representatives and to the number of women in the People’s Chamber and its committees, the biographies provide information on the social origin, party membership, educational and occupational training, and professional life of the individual women. The volume’s goal is to document these women’s extraordinary engagement in the GDR, for they not only held careers and fulfilled family duties, but also pursued possibilities for making political impact. The authors note at the outset that the book does not claim to be comprehensive, for it illuminates merely one aspect of the life stories of these women. This remark is important for making the reference work manageable.

  6. Land area change and fractional water maps in the Chenier Plain, Louisiana, following hurricane Rita

    Science.gov (United States)

    Palaseanu-Lovejoy, M.; Kranenburg, C.; Brock, J. C.

    2009-12-01

    The objective of this study is to develop a fractional water map at 30-m resolution scale using QuickBird and/or IKONOS high-resolution imagery as dependent variable to investigate the impact of hurricane Rita in the Chenier Plain, Louisiana. Eleven different indices were tested to obtain a high-resolution land / water classification on QuickBird (acquired on 05/23/2003) and IKONOS (acquired on 03/25/2006) images. The percent area covered by water in the high resolution images varied from 22 to 26% depending on the index used , with the simple ratio index (red band / NIR band) accounting for the lowest percent and the blue ratio index (blue band / sum(all bands)) for the highest percent. Using the ERDAS NLCD (National Land Cover Data) Mapping tool module, 100, 000 stratified random sample points with minimum 1000 points per stratum were selected from the high resolution dependent variable as training information for the independent variable layers. The rules for the regression tree were created using the data mining software Rulequest Cubist v. 2.05. This information was used to generate a fractional water map for the entire Landsat scene. The increase in water areas of about 10 - 15% between 2003 to 2006, as well as temporary changes in the water - land configurations are attributed to remnant flooding and removal of aquatic vegetation caused by hurricane Rita, and water level variations caused by tidal and / or meteorological variations between the acquisition dates of the satellite images. This analysis can assist in monitoring post-hurricane wetland recovery and assess trends in land loss due to extreme storm events, although estimation of permanent land loss cannot be made until wetland areas have the opportunity to recover from hurricane impacts.

  7. Groundwater Pollution Source Identification using Linked ANN-Optimization Model

    Science.gov (United States)

    Ayaz, Md; Srivastava, Rajesh; Jain, Ashu

    2014-05-01

    Groundwater is the principal source of drinking water in several parts of the world. Contamination of groundwater has become a serious health and environmental problem today. Human activities including industrial and agricultural activities are generally responsible for this contamination. Identification of groundwater pollution source is a major step in groundwater pollution remediation. Complete knowledge of pollution source in terms of its source characteristics is essential to adopt an effective remediation strategy. Groundwater pollution source is said to be identified completely when the source characteristics - location, strength and release period - are known. Identification of unknown groundwater pollution source is an ill-posed inverse problem. It becomes more difficult for real field conditions, when the lag time between the first reading at observation well and the time at which the source becomes active is not known. We developed a linked ANN-Optimization model for complete identification of an unknown groundwater pollution source. The model comprises two parts- an optimization model and an ANN model. Decision variables of linked ANN-Optimization model contain source location and release period of pollution source. An objective function is formulated using the spatial and temporal data of observed and simulated concentrations, and then minimized to identify the pollution source parameters. In the formulation of the objective function, we require the lag time which is not known. An ANN model with one hidden layer is trained using Levenberg-Marquardt algorithm to find the lag time. Different combinations of source locations and release periods are used as inputs and lag time is obtained as the output. Performance of the proposed model is evaluated for two and three dimensional case with error-free and erroneous data. Erroneous data was generated by adding uniformly distributed random error (error level 0-10%) to the analytically computed concentration

  8. Doktoritööd : [2007, Anne Lange jt.

    Index Scriptorium Estoniae

    2007-01-01

    20. veebr. kaitseb Anne Lange doktoritööd "The poetics of translation of Ants Oras". 19. jaan. kaitses Tuuli Oder doktoritööd "The model of contemporary professional foreign language teacher". 16. jaan. kaitses Tiit Maran doktoritööd "Conservation biology of the European mink, Mustela lutreola (Linnaeus 1761): decline and causes of extinction". 12. jaan. kaitses Maris Saagpakk doktoritööd "Deutschbaltische Autobiographien als Dokumente des Zeit- und Selbstempfindens: vom Ende des 19. Jh. bis zur Umsiedlung 1939"

  9. O Centro Espírita Redemptor e o tratamento de doença mental, 1910-1921 The Centro Espírita Redemptor and the treatment of mental illness, 1910-1921

    Directory of Open Access Journals (Sweden)

    André de Faria Pereira Neto

    2012-06-01

    Full Text Available O espiritismo é uma doutrina religiosa que surgiu na França durante o século XIX por meio da obra de Allan Kardec. No Brasil, assumiu certa originalidade: o espiritismo racional e científico cristão, liderado por Luiz de Mattos, foi uma de suas vertentes doutrinárias nacionais. Luiz de Mattos criou o Centro Espírita Redemptor onde, durante alguns anos, acompanhou o tratamento dos doentes mentais. O artigo analisa as características do tratamento espírita racional e científico cristão à doença mental e as estratégias que Luiz de Mattos adotou para defender sua forma de tratamento. Apresenta ainda algumas semelhanças e diferenças entre o tratamento espírita e o médico.Spiritism is a religious doctrine originated in France during the nineteenth century through the works of Allan Kardec. In Brazil, it assumed an original configuration: rational and scientific Christian spiritism, pioneered by Luiz de Mattos, was one of the national doctrinal variants. Luiz de Mattos created the Centro Espírita Redemptor where, for some years, he monitored the treatment of the mentally ill. The article analyzes the characteristics of rational and scientific Christian spiritism treatment applied to mental illness and the strategies that Luiz de Mattos adopted to defend his form of treatment. Some similarities and differences between spiritist and medical treatment are also outlined.

  10. A Kiss Lajos-díj 2016. évi nyertese: dr. Póczos Rita [Winner of the 2016 Lajos Kiss Prize: Dr Rita Póczos

    Directory of Open Access Journals (Sweden)

    Hoffmann, István

    2016-12-01

    Full Text Available The Lajos Kiss Prize, awarded every two or three years since 2006, is considered to be a highly prestigious award for young onomasticians. The 2016 winner of the prize is Dr Rita Póczos, senior lecturer at the Department of Hungarian Linguistics of the University of Debrecen. She was given this award for her contribution to Hungarian Historical Onomastics, especially for her research on place names.

  11. Sexuality and gender in contemporary women's Gothic fiction - Angela Carter's and Anne Rice's Vampires: Angela Carter's and Anne Rice's Vampires

    OpenAIRE

    Fernanda Sousa Carvalho

    2009-01-01

    xxx In this thesis, I provide an analysis of Angela Carter's and Anne Rice's works based on their depiction of vampires. My corpus is composed by Carter's short stories 'The Loves of Lady Purple' and 'The Lady of the House of Love' and by Rice's novels The Vampire Lestat and The Queen of the Damned. My analysis of this corpus is based on four approaches: a comparison between Carter's and Rice's works, supported by their common use of vampire characters; an investigation of how this use con...

  12. UPANJE IN SVOBODA V DELU STEPHENA KINGA RITA HAYWORTH AND SHAWSHANK REDEMPTION IN ALEXANDRE DUMAS GROF MONTE CRISTO

    OpenAIRE

    Kramar, Vesna

    2011-01-01

    Rita Hayworth and Shawshank Redemption Stephena Kinga in Grof Monte Cristo Alexandra Dumasa izhajata iz različnih literarnih žanrov in se razlikujeta v dogajanju, a imata kljub temu podobno motiviko in tematiko. V obeh zgodbah je nedolžen mož poslan v zapor, iz katerega je pobeg skorajda nemogoč, a se kljub temu obema uspe izmuzniti iz zapora na podoben način

  13. Satellite Assessment of Bio-Optical Properties of Northern Gulf of Mexico Coastal Waters Following Hurricanes Katrina and Rita

    OpenAIRE

    Lohrenz, Steven E.; Cai, Wei-Jun; Chen, Xiaogang; Tuel, Merritt

    2008-01-01

    The impacts of major tropical storms events on coastal waters include sediment resuspension, intense water column mixing, and increased delivery of terrestrial materials into coastal waters. We examined satellite imagery acquired by the Moderate Resolution Imaging Spectroradiometer (MODIS) ocean color sensor aboard the Aqua spacecraft following two major hurricane events: Hurricane Katrina, which made landfall on 29 August 2005, and Hurricane Rita, which made landfall on 24 September. MODIS A...

  14. Spatial-temporal water quality parameters evaluation of the Santa Rita river (BA with respect to the release of manipueira

    Directory of Open Access Journals (Sweden)

    Franklin Delano Porto Júnior

    2012-12-01

    Full Text Available The watershed of the river Santa Rita includes the towns of Simão and Campinhos, where exists about 150 flour houses. Campinhos is among the largest cassava processing facilities in the region, generating many direct and indirect jobs. Manipueira is a liquid residue originating from the cassava pressing and presents high pollutant potential due to its high amount of glucose and fructose, this potential is 25 times greater than the one from domestic sewer. This work had as objective the evaluation of possible impacts of manipueira release in the water quality of Santa Rita river. For this, the land use map was elaborated and the physiographic characterization developed, besides being performed six campaigns for water samples collection in four sampling points along the river. The obtained results indicated that the watershed is elongated, with low drainage efficiency and it is not prone to flooding. Estimated water quality parameters indicated that organic effluents from Campinhos and Simão impact the values of dissolved oxygen, electrical conductivity, salinity, ammonia, nitrite, nitrate and zinc, suggesting that the water quality of the river Santa Rita is affected by manipueira release. The concentrations of total phosphorus, iron and cooper were superior downstream of the Sewer Treatment Station. The river water was saline in the three sampling points most affected by the release of manipueira.

  15. Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu).

    Science.gov (United States)

    Luan, Jinwei; Li, Xianglan; Guo, Rutao; Liu, Shanshan; Luo, Hongyu; You, Qingshan

    2016-06-01

    Next generation sequencing and bio-informatic analyses were conducted to investigate the mechanism of reactivation of p53 and induction of tumor cell apoptosis (RITA)-enhancing X-ray susceptibility in FaDu cells. The cDNA was isolated from FaDu cells treated with 0 X-ray, 8 Gy X-ray, or 8 Gy X-ray + RITA. Then, cDNA libraries were created and sequenced using next generation sequencing, and each assay was repeated twice. Subsequently, differentially expressed genes (DEGs) were identified using Cuffdiff in Cufflinks and their functions were predicted by pathway enrichment analyses. Genes that were constantly up- or down-regulated in 8 Gy X-ray-treated FaDu cells and 8 Gy X-ray + RITA-treated FaDu cells were obtained as RITA genes. Afterward, the protein-protein interaction (PPI) relationships were obtained from the STRING database and a PPI network was constructed using Cytoscape. Furthermore, ClueGO was used for pathway enrichment analysis of genes in the PPI network. Total 2,040 and 297 DEGs were identified in FaDu cells treated with 8 Gy X-ray or 8 Gy X-ray + RITA, respectively. PARP3 and NEIL1 were enriched in base excision repair, and CDK1 was enriched in p53 signaling pathway. RFC2 and EZH2 were identified as RITA genes. In the PPI network, many interaction relationships were identified (e.g., RFC2-CDK1, EZH2-CDK1 and PARP3-EZH2). ClueGO analysis showed that RFC2 and EZH2 were related to cell cycle. RFC2, EZH2, CDK1, PARP3 and NEIL1 may be associated, and together enhance the susceptibility of FaDu cells treated with RITA to the deleterious effects of X-ray.

  16. Identification of differentially expressed genes associated with the enhancement of X-ray susceptibility by RITA in a hypopharyngeal squamous cell carcinoma cell line (FaDu)

    International Nuclear Information System (INIS)

    Luan, Jinwei; Li, Xianglan; Guo, Rutao; Liu, Shanshan; Luo, Hongyu; You, Qingshan

    2016-01-01

    Next generation sequencing and bio-informatic analyses were conducted to investigate the mechanism of reactivation of p53 and induction of tumor cell apoptosis (RITA)-enhancing X-ray susceptibility in FaDu cells. The cDNA was isolated from FaDu cells treated with 0 X-ray, 8 Gy X-ray, or 8 Gy X-ray + RITA. Then, cDNA libraries were created and sequenced using next generation sequencing, and each assay was repeated twice. Subsequently, differentially expressed genes (DEGs) were identified using Cuffdiff in Cufflinks and their functions were predicted by pathway enrichment analyses. Genes that were constantly up- or down-regulated in 8 Gy X-ray-treated FaDu cells and 8 Gy X-ray + RITA-treated FaDu cells were obtained as RITA genes. Afterward, the protein-protein interaction (PPI) relationships were obtained from the STRING database and a PPI network was constructed using Cytoscape. Furthermore, ClueGO was used for pathway enrichment analysis of genes in the PPI network. Total 2,040 and 297 DEGs were identified in FaDu cells treated with 8 Gy X-ray or 8 Gy X-ray + RITA, respectively. PARP3 and NEIL1 were enriched in base excision repair, and CDK1 was enriched in p53 signaling pathway. RFC2 and EZH2 were identified as RITA genes. In the PPI network, many interaction relationships were identified (e.g., RFC2-CDK1, EZH2-CDK1 and PARP3-EZH2). ClueGO analysis showed that RFC2 and EZH2 were related to cell cycle. RFC2, EZH2, CDK1, PARP3 and NEIL1 may be associated, and together enhance the susceptibility of FaDu cells treated with RITA to the deleterious effects of X-ray

  17. Solution of direct kinematic problem for Stewart-Gough platform with the use of analytical equation of plane

    Directory of Open Access Journals (Sweden)

    A. L. Lapikov

    2014-01-01

    Full Text Available The paper concerns the solution of direct kinematic problem for the Stewart-Gough platform of the type 6-3. The article represents a detailed analysis of methods of direct kinematic problem solution for platform mechanisms based on the parallel structures. The complexity of the problem solution is estimated for the mechanisms of parallel kinematics in comparison with the classic manipulators, characterized by the open kinematic chain.The method for the solution of this problem is suggested. It consists in setting up the correspondence between the functional dependence of Cartesian coordinates and the orientation of the moving platform centre on the values of generalized coordinates of the manipulator, which may be represented, in the case of platform manipulators, by the lengths of extensible arms to connect the foundation and the moving platform of the manipulator. The method is constructed in such a way that the solution of the direct kinematic problem reduces to solution of the analytical equation of plane where the moving platform is situated. The equation of the required plane is built according to three points which in this case are attachment points of moving platform joints. To define joints coordinates values it is necessary to generate a system of nine nonlinear equations. It ought to be noted that in generating a system of equation are used the equations with the same type of nonlinearity. The physical meaning of all nine equations of the system is Euclidean distance between the points of the manipulator. The location and orientation of the moving platform is represented as a homogeneous transformation matrix. The components of translation and rotation of this matrix can be defined through the required plane.The obtained theoretical results are supposed to be used in the decision support system during the complex research of multi-sectional manipulators of parallel kinematics to describe the geometrically similar 3D-prototype of the

  18. Geographical and Temporal Dynamics of Chaetocnema Pulicaria Populations and Their Role in Stewart's Disease of Corn in Iowa

    Energy Technology Data Exchange (ETDEWEB)

    Esker, Paul David [Iowa State Univ., Ames, IA (United States)

    2001-05-01

    This thesis is organized into five chapters. Chapter 1 is the introduction and justification, chapters 2 and 3 are journal papers, chapter 4 is a preliminary analysis of winter environmental variables and their use in forecasting for Stewart's disease of corn, and chapter 5 is general conclusions and discussion. References can be found at the end of each chapter, except chapter 5 and are specific to that chapter.

  19. Les crises soudanaises des années 80

    OpenAIRE

    Ahmed, Medani M.; al-Shazali, Salah al-Din; al-Shazali, Salah al-Din; al-Shazali, Salah al-Din; al-Shazali, Salah al-Din; Al-Tom, Abdulahi Osman; Babiker, Mustafa; Babiker, Mustafa; Blin, Louis; Conte, Édouard; Elmekki, Abdelgalil M.; Gore, Paul W.; Hamid, Mohammed Beshir; Ireton, François; Jacquemond, Richard

    2008-01-01

    Ce dossier est constitué, dans sa quasi-totalité, de contributions de chercheurs et universitaires soudanais proposant une analyse de certains des problèmes cruciaux que leur pays a connus depuis le début des années 80. Les articles qui le composent correspondent aux communications qui devaient initialement être présentées lors d’un colloque portant sur le même thème, prévu à Paris pour décembre 1991 et qui n'a pu avoir lieu du fait de l’impossibilité où se trouvaient certains de ses particip...

  20. Anne-Sylvie Catherin, Head of the Human Resources Department

    CERN Multimedia

    2009-01-01

    Anne-Sylvie Catherin has been appointed Head of the Human Resources Department with effect from 1 August 2009. Mrs Catherin is a lawyer specialized in International Administration and joined CERN in 1996 as legal advisor within the Office of the HR Department Head. After having been promoted to the position of Group Leader responsible for social and statutory conditions in 2000, Mrs Catherin was appointed Deputy of the Head of the Human Resources Department and Group Leader responsible for Strategy, Management and Development from 2005 to date. Since 2005, she has also served as a member of CCP and TREF. In the execution of her mandate as Deputy HR Department Head, Mrs Catherin closely assisted the HR Department Head in the organization of the Department and in devising new HR policies and strategies. She played an instrumental role in the last five-yearly review and in the revision of the Staff Rules and Regulations.

  1. 2011 : Année internationale de la chimie

    OpenAIRE

    2011-01-01

    Lors de la 63e assemblée générale des Nations Unies, 2011 a été proclamée année internationale de la chimie. En France, les acteurs de la chimie sont mobilisés pour promouvoir quatre objectifs : mettre l’accent sur l’importance de la chimie pour un développement durable dans tous les aspects de la vie sur la planète ; accroître chez les jeunes l’intérêt pour la chimie ; susciter l’enthousiasme pour une chimie tournée vers l’avenir ; célébrer les travaux de Marie Curie et la contribution des f...

  2. DESIGN OF A VISUAL INTERFACE FOR ANN BASED SYSTEMS

    Directory of Open Access Journals (Sweden)

    Ramazan BAYINDIR

    2008-01-01

    Full Text Available Artificial intelligence application methods have been used for control of many systems with parallel of technological development besides conventional control techniques. Increasing of artificial intelligence applications have required to education in this area. In this paper, computer based an artificial neural network (ANN software has been presented to learning and understanding of artificial neural networks. By means of the developed software, the training of the artificial neural network according to the inputs provided and a test action can be performed by changing the components such as iteration number, momentum factor, learning ratio, and efficiency function of the artificial neural networks. As a result of the study a visual education set has been obtained that can easily be adapted to the real time application.

  3. Hybrid LSA-ANN Based Home Energy Management Scheduling Controller for Residential Demand Response Strategy

    Directory of Open Access Journals (Sweden)

    Maytham S. Ahmed

    2016-09-01

    Full Text Available Demand response (DR program can shift peak time load to off-peak time, thereby reducing greenhouse gas emissions and allowing energy conservation. In this study, the home energy management scheduling controller of the residential DR strategy is proposed using the hybrid lightning search algorithm (LSA-based artificial neural network (ANN to predict the optimal ON/OFF status for home appliances. Consequently, the scheduled operation of several appliances is improved in terms of cost savings. In the proposed approach, a set of the most common residential appliances are modeled, and their activation is controlled by the hybrid LSA-ANN based home energy management scheduling controller. Four appliances, namely, air conditioner, water heater, refrigerator, and washing machine (WM, are developed by Matlab/Simulink according to customer preferences and priority of appliances. The ANN controller has to be tuned properly using suitable learning rate value and number of nodes in the hidden layers to schedule the appliances optimally. Given that finding proper ANN tuning parameters is difficult, the LSA optimization is hybridized with ANN to improve the ANN performances by selecting the optimum values of neurons in each hidden layer and learning rate. Therefore, the ON/OFF estimation accuracy by ANN can be improved. Results of the hybrid LSA-ANN are compared with those of hybrid particle swarm optimization (PSO based ANN to validate the developed algorithm. Results show that the hybrid LSA-ANN outperforms the hybrid PSO based ANN. The proposed scheduling algorithm can significantly reduce the peak-hour energy consumption during the DR event by up to 9.7138% considering four appliances per 7-h period.

  4. Summary of hydrologic testing of the Floridan aquifer system at Fort Stewart, coastal Georgia, 2009-2010

    Science.gov (United States)

    Gonthier, Gerald J.

    2011-01-01

    Two test wells were completed at Fort Stewart, coastal Georgia, to investigate the potential for using the Lower Floridan aquifer as a source of water to satisfy anticipated, increased water needs. The U.S. Geological Survey, in cooperation with the U.S. Department of the Army, completed hydrologic testing of the Floridan aquifer system at the study site, including flowmeter surveys, slug tests, and 24- and 72-hour aquifer tests by mid-March 2010. Analytical approaches and model simulation were applied to aquifer-test results to provide estimates of transmissivity and hydraulic conductivity of the multilayered Floridan aquifer system. Data from a 24-hour aquifer test of the Upper Floridan aquifer were evaluated by using the straight-line Cooper-Jacob analytical method. Data from a 72-hour aquifer test of the Lower Floridan aquifer were simulated by using axisymmetric model simulations. Results of aquifer testing indicated that the Upper Floridan aquifer has a transmissivity of 100,000 feet-squared per day, and the Lower Floridan aquifer has a transmissivity of 7,000 feet-squared per day. A specific storage for the Floridan aquifer system as a result of model calibration was 3E-06 ft–1. Additionally, during a 72-hour aquifer test of the Lower Floridan aquifer, a drawdown response was observed in two Upper Floridan aquifer wells, one of which was more than 1 mile away from the pumped well.

  5. Use of Temporary Immersion System (RITA in sugarcane the plants propagation by organogenesis

    Directory of Open Access Journals (Sweden)

    Laisyn Posada-Pérez

    2003-01-01

    Full Text Available The present work had as objective to study the possibilities to use the RITA, in the micropropagation plant via axillary buds of sugarcane and of the banana hybrid (Musa sp. AAAA cv. FHIA-01 and AAAB cv. FHIA-18. Two different culture medium i.e. multiplication and thickenment were studied in the multiplication phase of two varieties of sugarcane. It was also studied the number of initial explants to use (two, four and six, using as control flasks with explants liquid and semisolid medium. The number of immersions in 24 hours was analysed and also the time for culture media change was determined testing two periods, 15 days and 30 days respectively. Similar variables were studied for the case of the banana cultivar except for the medium culture. It was obtained like half of more appropriate cultivation for sugarcane that of multiplication with two explants, in the two used varieties, not presenting significant differences the times of change of half made to the 15 and 30 days. For the case of the banana cultivar employment of five explantes for FHIA-01 and three or five explantes for FHIA-18 to begin the multiplication allowed to reach the best results. Regarding the number of immersions it presented bigger superiority the treatment of three immersions during 24 hours, for both banana cultivars. Keys words: liquid medium, micropropagation, Musa, Saccharum

  6. Hazardous substances releases associated with Hurricanes Katrina and Rita in industrial settings, Louisiana and Texas.

    Science.gov (United States)

    Ruckart, Perri Zeitz; Orr, Maureen F; Lanier, Kenneth; Koehler, Allison

    2008-11-15

    The scientific literature concerning the public health response to the unprecedented hurricanes striking the Gulf Coast in August and September 2005 has focused mainly on assessing health-related needs and surveillance of injuries, infectious diseases, and other illnesses. However, the hurricanes also resulted in unintended hazardous substances releases in the affected states. Data from two states (Louisiana and Texas) participating in the Hazardous Substances Emergency Events Surveillance (HSEES) system were analyzed to describe the characteristics of hazardous substances releases in industrial settings associated with Hurricanes Katrina and Rita. HSEES is an active multi-state Web-based surveillance system maintained by the Agency for Toxic Substances and Disease Registry (ATSDR). In 2005, 166 hurricane-related hazardous substances events in industrial settings in Louisiana and Texas were reported. Most (72.3%) releases were due to emergency shut downs in preparation for the hurricanes and start-ups after the hurricanes. Emphasis is given to the contributing causal factors, hazardous substances released, and event scenarios. Recommendations are made to prevent or minimize acute releases of hazardous substances during future hurricanes, including installing backup power generation, securing equipment and piping to withstand high winds, establishing procedures to shutdown process operations safely, following established and up-to-date start-up procedures and checklists, and carefully performing pre-start-up safety reviews.

  7. Changes in microbial community structure in the wake of Hurricanes Katrina and Rita.

    Science.gov (United States)

    Amaral-Zettler, Linda A; Rocca, Jennifer D; Lamontagne, Michael G; Dennett, Mark R; Gast, Rebecca J

    2008-12-15

    Hurricanes have the potential to alter the structures of coastal ecosystems and generate pathogen-laden floodwaters thatthreaten public health. To examine the impact of hurricanes on urban systems, we compared microbial community structures in samples collected after Hurricane Katrina and before and after Hurricane Rita. We extracted environmental DNA and sequenced small-subunit rRNA (SSU rRNA) gene clone libraries to survey microbial communities in floodwater, water, and sediment samples collected from Lake Charles, Lake Pontchartrain, the 17th Street and Industrial Canals in New Orleans, and raw sewage. Correspondence analysis showed that microbial communities associated with sediments formed one cluster while communities associated with lake and Industrial Canal water formed a second. Communities associated with water from the 17th Street Canal and floodwaters collected in New Orleans showed similarity to communities in raw sewage and contained a number of sequences associated with possible pathogenic microbes. This suggests that a distinct microbial community developed in floodwaters following Hurricane Katrina and that microbial community structures as a whole might be sensitive indicators of ecosystem health and serve as "sentinels" of water quality in the environment.

  8. Promoting mental health recovery after hurricanes Katrina and Rita: what can be done at what cost.

    Science.gov (United States)

    Schoenbaum, Michael; Butler, Brittany; Kataoka, Sheryl; Norquist, Grayson; Springgate, Benjamin; Sullivan, Greer; Duan, Naihua; Kessler, Ronald C; Wells, Kenneth

    2009-08-01

    Concerns about mental health recovery persist after the 2005 Gulf storms. We propose a recovery model and estimate costs and outcomes. To estimate the costs and outcomes of enhanced mental health response to large-scale disasters using the 2005 Gulf storms as a case study. Decision analysis using state-transition Markov models for 6-month periods from 7 to 30 months after disasters. Simulated movements between health states were based on probabilities drawn from the clinical literature and expert input. A total of 117 counties/parishes across Louisiana, Mississippi, Alabama, and Texas that the Federal Emergency Management Agency designated as eligible for individual relief following hurricanes Katrina and Rita. Hypothetical cohort, based on the size and characteristics of the population affected by the Gulf storms. Intervention Enhanced mental health care consisting of evidence-based screening, assessment, treatment, and care coordination. Morbidity in 6-month episodes of mild/moderate or severe mental health problems through 30 months after the disasters; units of service (eg, office visits, prescriptions, hospital nights); intervention costs; and use of human resources. Full implementation would cost $1133 per capita, or more than $12.5 billion for the affected population, and yield 94.8% to 96.1% recovered by 30 months, but exceed available provider capacity. Partial implementation would lower costs and recovery proportionately. Evidence-based mental health response is feasible, but requires targeted resources, increased provider capacity, and advanced planning.

  9. Somatic experiencing treatment with social service workers following Hurricanes Katrina and Rita.

    Science.gov (United States)

    Leitch, M Laurie; Vanslyke, Jan; Allen, Marisa

    2009-01-01

    In a disaster, social service workers are often survivors themselves.This study examines whether somatic intervention using a brief (one to two session) stabilization model now called the Trauma Resiliency Model (TRM), which uses the skills of Somatic Experiencing (SE), can reduce the postdisaster symptoms of social service workers involved in postdisaster service delivery.The study was implemented with a nonrandom sample of 142 social service workers who were survivors of Hurricanes Katrina and Rita in New Orleans and Baton Rouge, Louisiana, two to three months after the disasters. Ninety-one participants received SE/TRM and were compared with a matched comparison group of 51 participants through the use of propensity score matching. All participants first received group psychoeducation. Results support the benefits of the brief intervention inspired by SE. The treatment group showed statistically significant gains in resiliency indicators and decreases in posttraumatic stress disorder symptoms. Although psychological symptoms increased in both groups at the three to four month follow-up, the treatment group's psychological symptoms were statistically lower than those of the comparison group.

  10. Lead distributions and risks in New Orleans following Hurricanes Katrina and Rita.

    Science.gov (United States)

    Abel, Michael T; Cobb, George P; Presley, Steven M; Ray, Gary L; Rainwater, Thomas R; Austin, Galen P; Cox, Stephen B; Anderson, Todd A; Leftwich, Blair D; Kendall, Ronald J; Suedel, Burton C

    2010-07-01

    During the last four years, significant effort has been devoted to understanding the effects that Hurricanes Katrina and Rita had on contaminant distribution and redistribution in New Orleans, Louisiana, USA, and the surrounding Gulf Coast area. Elevated concentrations were found for inorganic contaminants (including As, Fe, Pb, and V), several organic pollutants (polycyclic aromatic hydrocarbons, pesticides, and volatiles) and high concentration of bioaerosols, particularly Aeromonas and Vibrio. Data from different research groups confirm that some contaminant concentrations are elevated, that existing concentrations are similar to historical data, and that contaminants such as Pb and As may pose human health risks. Two data sets have been compiled in this article to serve as the foundation for preliminary risk assessments within greater New Orleans. Research from the present study suggests that children in highly contaminated areas of New Orleans may experience Pb exposure from soil ranging from 1.37 microg/d to 102 microg/d. These data are critical in the evaluation of children's health. Copyright (c) 2010 SETAC.

  11. The effects of hurricane Rita and subsequent drought on alligators in southwest Louisiana.

    Science.gov (United States)

    Lance, Valentine A; Elsey, Ruth M; Butterstein, George; Trosclair, Phillip L; Merchant, Mark

    2010-02-01

    Hurricane Rita struck the coast of southwest Louisiana in September 2005. The storm generated an enormous tidal surge of approximately four meters in height that inundated many thousands of acres of the coastal marsh with full strength seawater. The initial surge resulted in the deaths of a number of alligators and severely stressed those who survived. In addition, a prolonged drought (the lowest rainfall in 111 years of recorded weather data) following the hurricane resulted in highly saline conditions that persisted in the marsh for several months. We had the opportunity to collect 11 blood samples from alligators located on Holly Beach less than a month after the hurricane, but were unable to collect samples from alligators on Rockefeller Wildlife Refuge until February 2006. Conditions at Rockefeller Refuge did not permit systematic sampling, but a total of 201 samples were collected on the refuge up through August 2006. The blood samples were analyzed for sodium, potassium, chloride, osmolality, and corticosterone. Blood samples from alligators sampled on Holly Beach in October 2005, showed a marked elevation in plasma osmolality, sodium, chloride, potassium, corticosterone, and an elevated heterophil/lymphocyte ratio. Blood samples from alligators on Rockefeller Refuge showed increasing levels of corticosterone as the drought persisted and elevated osmolality and electrolytes. After substantial rainfall in July and August, these indices of osmotic stress returned to within normal limits. (c) 2009 Wiley-Liss, Inc.

  12. Ethnobotanical study of medicinal plants in the community of Santa Rita, Ituiutaba – Minas Gerais, Brazil

    Directory of Open Access Journals (Sweden)

    Glaucieli Siqueira Parreira Alves

    2013-09-01

    Full Text Available This paper aimed to inventory the plants used in popular medicine by members of the rural community of Santa Rita, in the town of Ituiutaba, Minas Gerais, Brazil. The evaluation was carried out through interviews, with a semi-structured questionnaire and subsequent collection of the plants indicated by informants. One conducted 47 interviews and 127 species were listed, belonging to 55 Angiosperm families. For obtaining the quantitative data, one calculated the percentage of the Main Use Concordance (cMUC of each species; for identifying the therapeutic indications with greater importance, one used the Informant Consensus Factor (ICF. The cMUC showed that 5.5% of the plants mentioned are widely used by the community. The predominant botanical families registered were Lamiaceae and Asteraceae, with 14 and 13 records, respectively. The indication of predominant use mainly involved illnesses related to an emotional disorder, as indicated by the ICF. One emphasizes that 60.7% of the plants mentioned in this paper are exotic species; thus, there’s a need for further studies in order to catalogue knowledge on the medicinal plants which are native to this region.

  13. The Multiple Life of Nerve Growth Factor: Tribute to Rita Levi-Montalcini (1909-2012

    Directory of Open Access Journals (Sweden)

    Luigi Aloe

    2013-03-01

    Full Text Available At the end of the 19th century, it was envisaged by Santiago Ramon y Cajal, but not, proven, that life at the neuronal level requires trophic support. The proof was obtained in the early 1950's by work initiated by Rita Levi-Montalcini (RLM discovering the nerve growth factor (NGF. Today, NGF and its relatives, collectively designated neurotrophins, are well recognized as mediators of multiple biological phenomena in health and disease, ranging from the neurotrophic through immunotrophic and epitheliotrophic to metabotrophic effects. Consequently, NGF and other neurotrophins are implicated in the pathogenesis of a large spectrum of neuronal and non-neuronal diseases, from Alzheimer's and other neurodegenerative diseases to atherosclerosis and other cardiometabolic diseases. Recent studies demonstrated the therapeutic potentials of NGF in these diseases, including ocular and cutaneous diseases. Furthermore, NGF TrkA receptor antagonists emerged as novel drugs for pain, prostate and breast cancer, melanoma, and urinary bladder syndromes. Altogether, NGF's multiple potential in health and disease is briefly described here.

  14. Recovery Migration after Hurricanes Katrina and Rita: Spatial Concentration and Intensification in the Migration System

    Science.gov (United States)

    Fussell, Elizabeth; DeWaard, Jack

    2015-01-01

    Changes in the human migration systems of Hurricane Katrina- and Rita-affected Gulf of Mexico coastline counties provide an example of how climate change may affect coastal populations. Crude climate change models predict a mass migration of “climate refugees,” but an emerging literature on environmental migration suggests most migration will be short-distance and short-duration within existing migration systems, with implications for the population recovery of disaster-struck places. In this research, we derive a series of hypotheses on recovery migration predicting how the migration system of hurricane-affected coastline counties in the Gulf of Mexico was likely to have changed between the pre-disaster and the recovery periods. We test these hypotheses using data from the Internal Revenue Service on annual county-level migration flows, comparing the recovery period migration system (2007–2009) to the pre-disaster period (1999–2004). By observing county-to-county ties and flows we find that recovery migration was strong, as the migration system of the disaster-affected coastline counties became more spatially concentrated while flows within it intensified and became more urbanized. Our analysis demonstrates how migration systems are likely to be affected by the more intense and frequent storms anticipated by climate change scenarios with implications for the population recovery of disaster-affected places. PMID:26084982

  15. Recovery Migration After Hurricanes Katrina and Rita: Spatial Concentration and Intensification in the Migration System.

    Science.gov (United States)

    Curtis, Katherine J; Fussell, Elizabeth; DeWaard, Jack

    2015-08-01

    Changes in the human migration systems of the Gulf of Mexico coastline counties affected by Hurricanes Katrina and Rita provide an example of how climate change may affect coastal populations. Crude climate change models predict a mass migration of "climate refugees," but an emerging literature on environmental migration suggests that most migration will be short-distance and short-duration within existing migration systems, with implications for the population recovery of disaster-stricken places. In this research, we derive a series of hypotheses on recovery migration predicting how the migration system of hurricane-affected coastline counties in the Gulf of Mexico was likely to have changed between the pre-disaster and the recovery periods. We test these hypotheses using data from the Internal Revenue Service on annual county-level migration flows, comparing the recovery period migration system (2007-2009) with the pre-disaster period (1999-2004). By observing county-to-county ties and flows, we find that recovery migration was strong: the migration system of the disaster-affected coastline counties became more spatially concentrated, while flows within it intensified and became more urbanized. Our analysis demonstrates how migration systems are likely to be affected by the more intense and frequent storms anticipated by climate change scenarios, with implications for the population recovery of disaster-affected places.

  16. Hazardous substances releases associated with Hurricanes Katrina and Rita in industrial settings, Louisiana and Texas

    International Nuclear Information System (INIS)

    Ruckart, Perri Zeitz; Orr, Maureen F.; Lanier, Kenneth; Koehler, Allison

    2008-01-01

    The scientific literature concerning the public health response to the unprecedented hurricanes striking the Gulf Coast in August and September 2005 has focused mainly on assessing health-related needs and surveillance of injuries, infectious diseases, and other illnesses. However, the hurricanes also resulted in unintended hazardous substances releases in the affected states. Data from two states (Louisiana and Texas) participating in the Hazardous Substances Emergency Events Surveillance (HSEES) system were analyzed to describe the characteristics of hazardous substances releases in industrial settings associated with Hurricanes Katrina and Rita. HSEES is an active multi-state Web-based surveillance system maintained by the Agency for Toxic Substances and Disease Registry (ATSDR). In 2005, 166 hurricane-related hazardous substances events in industrial settings in Louisiana and Texas were reported. Most (72.3%) releases were due to emergency shut downs in preparation for the hurricanes and start-ups after the hurricanes. Emphasis is given to the contributing causal factors, hazardous substances released, and event scenarios. Recommendations are made to prevent or minimize acute releases of hazardous substances during future hurricanes, including installing backup power generation, securing equipment and piping to withstand high winds, establishing procedures to shutdown process operations safely, following established and up-to-date start-up procedures and checklists, and carefully performing pre-start-up safety reviews

  17. Nephrologic Impact of Hurricanes Katrina and Rita in Areas Not Directly Affected.

    Science.gov (United States)

    Dossabhoy, Neville R; Qadri, Mashood; Beal, Lauren M

    2015-01-01

    Hurricanes Katrina and Rita resulted in enormous loss of life and disrupted the delivery of health care in areas affected by them. In causing mass movements of patients, natural disasters can overwhelm the resources of nephrology communities in areas not suffering direct damage. The following largely personal account evaluates the impact these hurricanes had upon the nephrology community, patients and health care providers alike, in areas not directly affected by the storms. Mass evacuation of hundreds of dialysis patients to surrounding areas overwhelmed the capacity of local hemodialysis centers. Non-availability of medical records in patients arriving without a supply of their routine medications led to confusion and sub-optimal treatment of conditions such as hypertension and congestive heart failure. Availability of cadaveric organs for transplantation was reduced in the surrounding areas, as the usual lines of communication and transportation were severed for several weeks. All of these issues led to prolong waiting times for patients on the transplant list. The hurricanes severely disrupted usual supply lines of medications to hospitals; certain rare conditions may be seen in higher numbers as a result of the shortages induced. We present the interesting surge in cases of acute kidney injury secondary to use of intravenous immune globulin.

  18. Tres cartas para la traición de Rita Hayworth

    Directory of Open Access Journals (Sweden)

    José Amícola

    1996-11-01

    Full Text Available El artículo trata la relación entre los manuscritos previos a la escritura de la primera novela de Manuel Puig y la novela terminada [de 1968]. El capítulo inserto cerca del final de la novela [en forma de'carta anónima'] habla asimismo de la voluntad de conformar una estructura armónica, donde surja un movimiento bipolar de ritmo distendido versus otro agitado, a la vez que obliga a la participación del lector en la tarea de la identidad del presunto remitente del anónimo. La segunda carta analizada [el último capítulo de la novela] nos lleva al centro de una crítica genética en la que se evidencia el trabajo de pulimiento del broche final, como clave de todo el texto. La tercera carta analizada aquí [borrador de carta del escritor a la actriz Rita Hayworth, de 1966], es un paratexto [es decir: un texto no ficcional independiente]. El borrador de esa carta a la actriz que da nombre a la obra sirve al geneticista como piedra de toque para descubrir la intención autorial con respecto al núcleo argumental de la novela, un núcleo que los esquemas pre-textuales anunciaban como 'la verdad'

  19. Os Episódios de Rita Patrício

    Directory of Open Access Journals (Sweden)

    Gustavo Rubim

    2014-12-01

    O texto propõe uma leitura do livro Episódios: da teorização estética em Fernando Pessoa, da au­toria de Rita Patrício. Datado de 2012, o livro só ficou realmente pronto e publicado em 2014. A leitura de­fende a originalidade deste exame minucioso dos textos de teoria estética e literária de Fernando Pessoa, tanto pela maneira como os trata autonomamente da obra poética e os estuda na sua escrita específica, quanto pelo efeito de deslocação dos tópicos habituais na análise do programa modernista português. A crí­tica do idealismo pessoano e da noção de obra enquanto totalidade or­gânica são sublinhados enquanto gestos condutores de toda a pesquisa. Propõem-se articulações com outros ensaios recentes que em Portugal procedem à revisão da crítica e da hermenêutica pes­soana.

  20. In vitro propagation of Phalaenopsis (Orchidaceae from protocorms, using the temporary inmersion system "RITA"

    Directory of Open Access Journals (Sweden)

    Jorge Mario Tirado

    2005-01-01

    Full Text Available In order to massively propagate Phalaenopsis orchids, three months old in vitro protocorms were transferred to RITA® vessels. The evaluation factors were the sucrose concentration in the culture medium and the frequency immersion. There was a set of five pairs of RITA® vessels with liquid culture medium containing sucrose at 0,15, 30, 45, 60 g/L. A half-strength MS medium plus vitamins, supplemented with vitamins and thidiazuron (5 mg/L was used. The experiment had two stages, each lasting two months. Each stage had a one minute immersion. The first stage had a four hour immersion frequency and the second one had an eight hour immersion frequency. Results showed that the best proliferating response was reached in a 15 g/L of sucrose medium with one minute of immersion time every four hours, resulting in 8,2 adventitious protocorms per protocorm per month. Key words: Phalaenopsis, protocorm, in vitro propagation, temporary immersion, RITA.

  1. A Green Prison: Santa Rita Jail Creeps Towards Zero Net Energy (ZNE)

    Energy Technology Data Exchange (ETDEWEB)

    Marnay, Chris; DeForest, Nicholas; Stadler, Michael; Donadee, Jon; Dierckxsens, Carlos; Mendes, Goncalo; Lai, Judy; Cardoso, Goncalo Ferreira

    2011-03-18

    A large project is underway at Alameda County's twenty-year old 45 ha 4,000-inmate Santa Rita Jail, about 70 km east of San Francisco. Often described as a green prison, it has a considerable installed base of distributed energy resources including a seven-year old 1.2 MW PV array, a four-year old 1 MW fuel cell with heat recovery, and efficiency investments. A current US$14 M expansion will add approximately 2 MW of NaS batteries, and undetermined wind capacity and a concentrating solar thermal system. This ongoing effort by a progressive local government with considerable Federal and State support provides some excellent lessons for the struggle to lower building carbon footprint. The Distributed Energy Resources Customer Adoption Model (DER-CAM) finds true optimal combinations of equipment and operating schedules for microgrids that minimize energy bills and/or carbon emissions without 2 of 12 significant searching or rules-of-thumb prioritization, such as"efficiency first then on-site generation." The results often recommend complex systems, and sensitivities show how policy changes will affect choices. This paper reports an analysis of the historic performance of the PV system and fuel cell, describes the complex optimization applied to the battery scheduling, and shows how results will affect the jail's operational costs, energy consumption, and carbon footprint. DER-CAM is used to assess the existing and proposed DER equipment in its ability to reduce tariff charges.

  2. Hazardous substances releases associated with Hurricanes Katrina and Rita in industrial settings, Louisiana and Texas

    Energy Technology Data Exchange (ETDEWEB)

    Ruckart, Perri Zeitz [Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA (United States)], E-mail: afp4@cdc.gov; Orr, Maureen F. [Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA (United States); Lanier, Kenneth; Koehler, Allison [Louisiana Department of Health and Hospitals, Office of Public Health, New Orleans, LA (United States)

    2008-11-15

    The scientific literature concerning the public health response to the unprecedented hurricanes striking the Gulf Coast in August and September 2005 has focused mainly on assessing health-related needs and surveillance of injuries, infectious diseases, and other illnesses. However, the hurricanes also resulted in unintended hazardous substances releases in the affected states. Data from two states (Louisiana and Texas) participating in the Hazardous Substances Emergency Events Surveillance (HSEES) system were analyzed to describe the characteristics of hazardous substances releases in industrial settings associated with Hurricanes Katrina and Rita. HSEES is an active multi-state Web-based surveillance system maintained by the Agency for Toxic Substances and Disease Registry (ATSDR). In 2005, 166 hurricane-related hazardous substances events in industrial settings in Louisiana and Texas were reported. Most (72.3%) releases were due to emergency shut downs in preparation for the hurricanes and start-ups after the hurricanes. Emphasis is given to the contributing causal factors, hazardous substances released, and event scenarios. Recommendations are made to prevent or minimize acute releases of hazardous substances during future hurricanes, including installing backup power generation, securing equipment and piping to withstand high winds, establishing procedures to shutdown process operations safely, following established and up-to-date start-up procedures and checklists, and carefully performing pre-start-up safety reviews.

  3. The multiple life of nerve growth factor: tribute to rita levi-montalcini (1909-2012).

    Science.gov (United States)

    Aloe, Luigi; Chaldakov, George N

    2013-03-01

    At the end of the 19(th) century, it was envisaged by Santiago Ramon y Cajal, but not, proven, that life at the neuronal level requires trophic support. The proof was obtained in the early 1950's by work initiated by Rita Levi-Montalcini (RLM) discovering the nerve growth factor (NGF). Today, NGF and its relatives, collectively designated neurotrophins, are well recognized as mediators of multiple biological phenomena in health and disease, ranging from the neurotrophic through immunotrophic and epitheliotrophic to metabotrophic effects. Consequently, NGF and other neurotrophins are implicated in the pathogenesis of a large spectrum of neuronal and non-neuronal diseases, from Alzheimer's and other neurodegenerative diseases to atherosclerosis and other cardiometabolic diseases. Recent studies demonstrated the therapeutic potentials of NGF in these diseases, including ocular and cutaneous diseases. Furthermore, NGF TrkA receptor antagonists emerged as novel drugs for pain, prostate and breast cancer, melanoma, and urinary bladder syndromes. Altogether, NGF's multiple potential in health and disease is briefly described here.

  4. Homage to Rita Levi-Montalcini, the queen of modern neuroscience.

    Science.gov (United States)

    Aloe, Luigi; Chaldakov, George N

    2013-08-01

    The first cell growth factor, nerve growth factor (NGF), was discovered by Rita Levi-Montalcini (RLM) in the early 1950s. Originally identified as neurite outgrowth-stimulating factor, later studies revealed that non-neuronal cells, including immune cells, endothelial cells, cardiomyocytes, pancreatic beta cells, prostate epithelial and adipose tissue cells, were also targets for and/or sources of NGF. Nerve growth factor is well recognised as mediating multiple biological phenomena, ranging from the neurotrophic through immunotrophic and epitheliotrophic to metabotrophic effects. Consequently, NGF and other members of the neurotrophin family are implicated in the pathogenesis of a large spectrum of neuronal and non-neuronal diseases, ranging from Alzheimer's and other neurodegenerative diseases to atherosclerosis and cardiometabolic disorders. Recent studies have demonstrated the therapeutic potentials of NGF in these conditions, including ocular and cutaneous diseases. NGF TrkA receptor antagonists emerged as novel drugs for pain, prostate and breast cancer, melanoma and urinary bladder syndromes. Here, we briefly describe the 'unpredictable' ideogenesis of the discovery of NGF, a eureka in the neuroscience. © 2013 International Federation for Cell Biology.

  5. Impacts of Hurricanes Katrina and Rita on the microbial landscape of the New Orleans area.

    Science.gov (United States)

    Sinigalliano, C D; Gidley, M L; Shibata, T; Whitman, D; Dixon, T H; Laws, E; Hou, A; Bachoon, D; Brand, L; Amaral-Zettler, L; Gast, R J; Steward, G F; Nigro, O D; Fujioka, R; Betancourt, W Q; Vithanage, G; Mathews, J; Fleming, L E; Solo-Gabriele, H M

    2007-05-22

    Floodwaters in New Orleans from Hurricanes Katrina and Rita were observed to contain high levels of fecal indicator bacteria and microbial pathogens, generating concern about long-term impacts of these floodwaters on the sediment and water quality of the New Orleans area and Lake Pontchartrain. We show here that fecal indicator microbe concentrations in offshore waters from Lake Pontchartrain returned to prehurricane concentrations within 2 months of the flooding induced by these hurricanes. Vibrio and Legionella species within the lake were more abundant in samples collected shortly after the floodwaters had receded compared with samples taken within the subsequent 3 months; no evidence of a long-term hurricane-induced algal bloom was observed. Giardia and Cryptosporidium were detected in canal waters. Elevated levels of fecal indicator bacteria observed in sediment could not be solely attributed to impacts from floodwaters, as both flooded and nonflooded areas exhibited elevated levels of fecal indicator bacteria. Evidence from measurements of Bifidobacterium and bacterial diversity analysis suggest that the fecal indicator bacteria observed in the sediment were from human fecal sources. Epidemiologic studies are highly recommended to evaluate the human health effects of the sediments deposited by the floodwaters.

  6. Anne Veesaar astus Valgas üles uudses rollis / Jaan Rapp

    Index Scriptorium Estoniae

    Rapp, Jaan

    2010-01-01

    2010. aasta iga kuu viimasel reedel esitab näitlejanna Anne Veesaar Raadio Ruudus katkendeid Valgamaa kirjanike loomingust. 14. jaanuaril kohtumisel lugejatega rääkis Valgas sündinud näitlejanna oma elulooraamatust "Anne Veesaar : elus, see on kõige tähtsam", mille on kirja pannud Helen Eelrand, ja oma praegustest tegemistest

  7. Visual NNet: An Educational ANN's Simulation Environment Reusing Matlab Neural Networks Toolbox

    Science.gov (United States)

    Garcia-Roselló, Emilio; González-Dacosta, Jacinto; Lado, Maria J.; Méndez, Arturo J.; Garcia Pérez-Schofield, Baltasar; Ferrer, Fátima

    2011-01-01

    Artificial Neural Networks (ANN's) are nowadays a common subject in different curricula of graduate and postgraduate studies. Due to the complex algorithms involved and the dynamic nature of ANN's, simulation software has been commonly used to teach this subject. This software has usually been developed specifically for learning purposes, because…

  8. Flow forecast by SWAT model and ANN in Pracana basin, Portugal

    NARCIS (Netherlands)

    Demirel, M.C.; Venancio, Anabela; Kahya, Ercan

    2009-01-01

    This study provides a unique opportunity to analyze the issue of flow forecast based on the soil and water assessment tool (SWAT) and artificial neural network (ANN) models. In last two decades, the ANNs have been extensively applied to various water resources system problems. In this study, the

  9. Acid-base disturbances in nephrotic syndrome: analysis using the CO2/HCO3 method (traditional Boston model) and the physicochemical method (Stewart model).

    Science.gov (United States)

    Kasagi, Tomomichi; Imai, Hirokazu; Miura, Naoto; Suzuki, Keisuke; Yoshino, Masabumi; Nobata, Hironobu; Nagai, Takuhito; Banno, Shogo

    2017-10-01

    The Stewart model for analyzing acid-base disturbances emphasizes serum albumin levels, which are ignored in the traditional Boston model. We compared data derived using the Stewart model to those using the Boston model in patients with nephrotic syndrome. Twenty-nine patients with nephrotic syndrome and six patients without urinary protein or acid-base disturbances provided blood and urine samples for analysis that included routine biochemical and arterial blood gas tests, plasma renin activity, and aldosterone. The total concentration of non-volatile weak acids (A TOT ), apparent strong ion difference (SIDa), effective strong ion difference (SIDe), and strong ion gap (SIG) were calculated according to the formulas of Agrafiotis in the Stewart model. According to the Boston model, 25 of 29 patients (90%) had alkalemia. Eighteen patients had respiratory alkalosis, 11 had metabolic alkalosis, and 4 had both conditions. Only three patients had hyperreninemic hyperaldosteronism. The Stewart model demonstrated respiratory alkalosis based on decreased PaCO 2 , metabolic alkalosis based on decreased A TOT , and metabolic acidosis based on decreased SIDa. We could diagnose metabolic alkalosis or acidosis with a normal anion gap after comparing delta A TOT [(14.09 - measured A TOT ) or (11.77 - 2.64 × Alb (g/dL))] and delta SIDa [(42.7 - measured SIDa) or (42.7 - (Na + K - Cl)]). We could also identify metabolic acidosis with an increased anion gap using SIG > 7.0 (SIG = 0.9463 × corrected anion gap-8.1956). Patients with nephrotic syndrome had primary respiratory alkalosis, decreased A TOT due to hypoalbuminemia (power to metabolic alkalosis), and decreased levels of SIDa (power to metabolic acidosis). We could detect metabolic acidosis with an increased anion gap by calculating SIG. The Stewart model in combination with the Boston model facilitates the analysis of complex acid-base disturbances in nephrotic syndrome.

  10. Inability of p53-reactivating compounds Nutlin-3 and RITA to overcome p53 resistance in tumor cells deficient in p53Ser46 phosphorylation.

    Science.gov (United States)

    Ma, Teng; Yamada, Shumpei; Ichwan, Solachuddin J A; Iseki, Sachiko; Ohtani, Kiyoshi; Otsu, Megumi; Ikeda, Masa-Aki

    2012-01-20

    The p53 tumor suppressor protein plays key roles in protecting cells from tumorigenesis. Phosphorylation of p53 at Ser46 (p53Ser46) is considered to be a crucial modification regulating p53-mediated apoptosis. Because the activity of p53 is impaired in most human cancers, restoration of wild-type p53 (wt-p53) function by its gene transfer or by p53-reactivating small molecules has been extensively investigated. The p53-reactivating compounds Nutlin-3 and RITA activate p53 in the absence of genotoxic stress by antagonizing the action of its negative regulator Mdm2. Although controversial, Nutlin-3 was shown to induce p53-mediated apoptosis in a manner independent of p53 phosphorylation. Recently, RITA was shown to induce apoptosis by promoting p53Ser46 phosphorylation. Here we examined whether Nutlin-3 or RITA can overcome resistance to p53-mediated apoptosis in p53-resistant tumor cell lines lacking the ability to phosphorylate p53Ser46. We show that Nutlin-3 did not rescue the apoptotic defect of a Ser46 phosphorylation-defective p53 mutant in p53-sensitive tumor cells, and that RITA neither restored p53Ser46 phosphorylation nor induced apoptosis in p53Ser46 phosphorylation-deficient cells retaining wt-p53. Furthermore, treatment with Nutlin-3 or RITA together with adenoviral p53 gene transfer also failed to induce apoptosis in p53Ser46 phosphorylation-deficient cells either expressing or lacking wt-p53. These results indicate that neither Nutlin-3 nor RITA in able to induce p53-mediated apoptosis in the absence of p53Ser46 phosphorylation. Thus, the dysregulation of this phosphorylation in tumor cells may be a critical factor that limits the efficacy of these p53-based cancer therapies. Copyright © 2011 Elsevier Inc. All rights reserved.

  11. RITA (Reactivating p53 and Inducing Tumor Apoptosis) is efficient against TP53abnormal myeloma cells independently of the p53 pathway.

    Science.gov (United States)

    Surget, Sylvanie; Descamps, Géraldine; Brosseau, Carole; Normant, Vincent; Maïga, Sophie; Gomez-Bougie, Patricia; Gouy-Colin, Nadège; Godon, Catherine; Béné, Marie C; Moreau, Philippe; Le Gouill, Steven; Amiot, Martine; Pellat-Deceunynck, Catherine

    2014-06-14

    The aim of this study was to evaluate the efficacy of the p53-reactivating drugs RITA and nutlin3a in killing myeloma cells. A large cohort of myeloma cell lines (n = 32) and primary cells (n = 21) was used for this study. This cohort contained cell lines with various TP53 statuses and primary cells with various incidences of deletion of chromosome 17. Apoptosis was evaluated using flow cytometry with Apo2.7 staining of the cell lines or via the loss of the myeloma-specific marker CD138 in primary cells. Apoptosis was further confirmed by the appearance of a subG1 peak and the activation of caspases 3 and 9. Activation of the p53 pathway was monitored using immunoblotting via the expression of the p53 target genes p21, Noxa, Bax and DR5. The involvement of p53 was further studied in 4 different p53-silenced cell lines. Both drugs induced the apoptosis of myeloma cells. The apoptosis that was induced by RITA was not related to the TP53 status of the cell lines or the del17p status of the primary samples (p = 0.52 and p = 0.80, respectively), and RITA did not commonly increase the expression level of p53 or p53 targets (Noxa, p21, Bax or DR5) in sensitive cells. Moreover, silencing of p53 in two TP53(mutated) cell lines failed to inhibit apoptosis that was induced by RITA, which confirmed that RITA-induced apoptosis in myeloma cells was p53 independent. In contrast, apoptosis induced by nutlin3a was directly linked to the TP53 status of the cell lines and primary samples (p RITA, in contrast to nutlin3a, effectively induced apoptosis in a subset of MM cells independently of p53. The findings and could be of interest for patients with a 17p deletion, who are resistant to current therapies.

  12. Assessment of ANN and SVM models for estimating normal direct irradiation (H_b)

    International Nuclear Information System (INIS)

    Santos, Cícero Manoel dos; Escobedo, João Francisco; Teramoto, Érico Tadao; Modenese Gorla da Silva, Silvia Helena

    2016-01-01

    Highlights: • The performance of SVM and ANN in estimating Normal Direct Irradiation (H_b) was evaluated. • 12 models using different input variables are developed (hourly and daily partitions). • The most relevant input variables for DNI are kt, H_s_c and insolation ratio (r′ = n/N). • Support Vector Machine (SVM) provides accurate estimates and outperforms the Artificial Neural Network (ANN). - Abstract: This study evaluates the estimation of hourly and daily normal direct irradiation (H_b) using machine learning techniques (ML): Artificial Neural Network (ANN) and Support Vector Machine (SVM). Time series of different meteorological variables measured over thirteen years in Botucatu were used for training and validating ANN and SVM. Seven different sets of input variables were tested and evaluated, which were chosen based on statistical models reported in the literature. Relative Mean Bias Error (rMBE), Relative Root Mean Square Error (rRMSE), determination coefficient (R"2) and “d” Willmott index were used to evaluate ANN and SVM models. When compared to statistical models which use the same set of input variables (R"2 between 0.22 and 0.78), ANN and SVM show higher values of R"2 (hourly models between 0.52 and 0.88; daily models between 0.42 and 0.91). Considering the input variables, atmospheric transmissivity of global radiation (kt), integrated solar constant (H_s_c) and insolation ratio (n/N, n is sunshine duration and N is photoperiod) were the most relevant in ANN and SVM models. The rMBE and rRMSE values in the two time partitions of SVM models are lower than those obtained with ANN. Hourly ANN and SVM models have higher rRMSE values than daily models. Optimal performance with hourly models was obtained with ANN4"h (rMBE = 12.24%, rRMSE = 23.99% and “d” = 0.96) and SVM4"h (rMBE = 1.75%, rRMSE = 20.10% and “d” = 0.96). Optimal performance with daily models was obtained with ANN2"d (rMBE = −3.09%, rRMSE = 18.95% and “d” = 0

  13. Mineral, Energy, and Fertilizer Resources of the North Coast of Peru: Perspective from the Santa Rita B Archaeological Site

    Science.gov (United States)

    Brooks, William E.; Kent, Jonathan D.; Willett, Jason C.

    2004-01-01

    The Santa Rita B archaeological site is in the Chao Valley, approximately 65 km southeast of Trujillo, northern Peru. Location of Santa Rita B at the emergence of several drainages from the Andean cordillera is an important factor in the almost continuous occupation of the site over the past 3,000 years. Mineral resources are abundant throughout the Andes; however, the north coast of Peru was an important center for pre-Columbian mining, metallurgy, and craftsmanship. Success of the Chavin, Moche, Chimu, and other north coast cultures is directly related to the availability and exploitation of mineral and energy resources that include: gold (?silver), as electrum, mainly from placers, and copper from local oxide and carbonate occurrences and from sulfides related to copper porphyry occurrences in the cordillera. An alloy of these three metals is referred to as tumbaga, which is the primary material for Andean metalcraft. Anthracite was used for mirrors by north coast cultures and is available near Rio Chicama, Rio Santa, and east of Santa Rita B. These outcrops are a part of the Alto Chicama, Peru's largest coalfield, which extends from Rio Chicama, in the north, for 200 km southward to Rio Santa. Charcoal from the algorrobo tree and llama dung are considered to be the common pre-Columbian energy sources for cooking and metalwork; however, availability and the higher heat content of anthracite indicate that it was used in metallurgical applications. Bitumen is available from petroleum seeps near Talara, north of the study area, and may have been used as glue or as cement. Hematite, goethite, limonite, and manganese oxides from clay-altered volcanic rock may have provided color and material for ceramics. Guano from the Islas Gua?apes, Chinchas, and Ballestas was used as fertilizer for cotton and other crops.

  14. After Hurricanes Katrina and Rita: gender differences in health and religiosity in middle-aged and older adults.

    Science.gov (United States)

    Brown, Jennifer Silva; Cherry, Katie E; Marks, Loren D; Jackson, Erin M; Volaufova, Julia; Lefante, Christina; Jazwinski, S Michal

    2010-11-01

    We examined health-related quality of life in adults in the Louisiana Health Aging Study (LHAS) after Hurricanes Katrina and Rita (HK/R) that made landfall on the U.S. Gulf Coast region in 2005. Analyses of pre- and post-disaster SF-36 scores yielded changes in physical function and bodily pain. Mental health scores were lower for women than men. Gender differences were observed in religious beliefs and religious coping, favoring women. Religious beliefs and religious coping were negatively correlated with physical function, implying that stronger reliance on religiosity as a coping mechanism may be more likely among those who are less physically capable.

  15. CREACIÓN DE UN METAVERSO EN OPENSIM PARA LA UNIVERSIDAD DISTRITAL DENTRO DE LA RED RITA-UD

    Directory of Open Access Journals (Sweden)

    Nicolás Torres Vallejo

    2013-01-01

    Full Text Available Este paper contempla el montaje de un segmento de red inalámbrico para la red RITA-UD con el fin de brindar acceso a contenidos multimedia a través de un mundo virtual creado en OPENSIM. Los contenidos de las emisiones de streaming se encuentran almacenados en un servidor ubicado en el centro de computación de alto desempeño, CECAD. Al tiempo  que se realizaron pruebas de streaming multicast, se capturaron dichas transmisiones mediante el sniffer de paquetes WireShark con el fin de determinar parámetros de QoS que caractericen el canal.

  16. A Sensitive ANN Based Differential Relay for Transformer Protection with Security against CT Saturation and Tap Changer Operation

    OpenAIRE

    KHORASHADI-ZADEH, Hassan; LI, Zuyi

    2014-01-01

    This paper presents an artificial neural network (ANN) based scheme for fault identification in power transformer protection. The proposed scheme is featured by the application of ANN to identifying system patterns, the unique choice of harmonics of positive sequence differential currents as ANN inputs, the effective handling of current transformer (CT) saturation with an ANN based approach, and the consideration of tap changer position for correcting secondary CT current. Performanc...

  17. News from HR: a word from Anne-Sylvie Catherin

    CERN Multimedia

    2016-01-01

    Anne-Sylvie Catherin, head of HR Department, looks back over her years at CERN before taking up her new position at the European Central Bank.   At the end of July, I will be leaving CERN on a special leave of absence to take up a new position at the European Central Bank. This is a new chapter in my career, in a new context with its own challenges, and as I prepare for it, I would like to take a little time to look back over my years at CERN and share with you the enriching journey it has been, both for myself and for HR. It has always been my strong belief that any organisation’s greatest asset is its people. When an HR professional believes that, it’s only a short step to the conclusion that the best way to nurture those people is by adopting a professional approach to HR. In this respect, I arrived at a very fortuitous time. Enrico Chiaveri was head of HR and, although his background is in physics, we shared that same conviction. Enrico was the icebreaker in driving change, a...

  18. The Sacred Object: Anne Carson and Simone Weil

    Directory of Open Access Journals (Sweden)

    Elizabeth Coles

    2014-01-01

    Full Text Available Este artículo examina la relación entre la lectura crítica y el objeto crítico en laobra de la poeta y ensayista canadiense Anne Carson, principalmente los textosque surgen de su largo acercamiento a los escritos de la filósofa y mística cristiana Simone Weil. Mi lectura de Carson se centra en los deseos conflictuales de la relación crítica que se encuentran confesados y no confesados en su obra, y en las formas de intimidad que sus respuestas logran con la obra de Weil. Agudizadas por su encuentro con el pensamiento y la fe de Weil, las preguntasde Carson para la crítica ―sobre sus propios objetos y la resistencia de ellos ala interpretación, sobre la distinción entre crítica y literatura, y sobre la vanidadde la estética de la crítica misma― encuentran su articulación en varios génerosde la escritura: estudiando la complicidad de cada uno de estos con Weil, yla capacidad de cada uno a radicalizar sus cuestiones, llego a unas conclusionspropias para la crítica literaria.

  19. Daily reservoir inflow forecasting combining QPF into ANNs model

    Science.gov (United States)

    Zhang, Jun; Cheng, Chun-Tian; Liao, Sheng-Li; Wu, Xin-Yu; Shen, Jian-Jian

    2009-01-01

    Daily reservoir inflow predictions with lead-times of several days are essential to the operational planning and scheduling of hydroelectric power system. The demand for quantitative precipitation forecasting (QPF) is increasing in hydropower operation with the dramatic advances in the numerical weather prediction (NWP) models. This paper presents a simple and an effective algorithm for daily reservoir inflow predictions which solicits the observed precipitation, forecasted precipitation from QPF as predictors and discharges in following 1 to 6 days as predicted targets for multilayer perceptron artificial neural networks (MLP-ANNs) modeling. An improved error back-propagation algorithm with self-adaptive learning rate and self-adaptive momentum coefficient is used to make the supervised training procedure more efficient in both time saving and search optimization. Several commonly used error measures are employed to evaluate the performance of the proposed model and the results, compared with that of ARIMA model, show that the proposed model is capable of obtaining satisfactory forecasting not only in goodness of fit but also in generalization. Furthermore, the presented algorithm is integrated into a practical software system which has been severed for daily inflow predictions with lead-times varying from 1 to 6 days of more than twenty reservoirs operated by the Fujian Province Grid Company, China.

  20. Geomorphic and ecological effects of Hurricanes Katrina and Rita on coastal Louisiana marsh communities

    Science.gov (United States)

    Piazza, Sarai C.; Steyer, Gregory D.; Cretini, Kari F.; Sasser, Charles E.; Visser, Jenneke M.; Holm, Guerry O.; Sharp, Leigh A.; Evers, D. Elaine; Meriwether, John R.

    2011-01-01

    Hurricanes Katrina and Rita made landfall in 2005, subjecting the coastal marsh communities of Louisiana to various degrees of exposure. We collected data after the storms at 30 sites within fresh (12), brackish/intermediate (12), and saline (6) marshes to document the effects of saltwater storm surge and sedimentation on marsh community dynamics. The 30 sites were comprised of 15 pairs. Most pairs contained one site where data collection occurred historically (that is, prestorms) and one Coastwide Reference Monitoring System site. Data were collected from spring 2006 to fall 2007 on vegetative species composition, percentage of vegetation cover, aboveground and belowground biomass, and canopy reflectance, along with discrete porewater salinity, hourly surface-water salinity, and water level. Where available, historical data acquired before Hurricanes Katrina and Rita were used to compare conditions and changes in ecological trajectories before and after the hurricanes. Sites experiencing direct and indirect hurricane influences (referred to in this report as levels of influence) were also identified, and the effects of hurricane influence were tested on vegetation and porewater data. Within fresh marshes, porewater salinity was greater in directly impacted areas, and this heightened salinity was reflected in decreased aboveground and belowground biomass and increased cover of disturbance species in the directly impacted sites. At the brackish/intermediate marsh sites, vegetation variables and porewater salinity were similar in directly and indirectly impacted areas, but porewater salinity was higher than expected throughout the study. Interestingly, directly impacted saline marsh sites had lower porewater salinity than indirectly impacted sites, but aboveground biomass was greater at the directly impacted sites. Because of the variable and site-specific nature of hurricane influences, we present case studies to help define postdisturbance baseline conditions in

  1. Estudo etnobotânico de plantas medicinais na comunidade de Santa Rita, Ituiutaba – MG

    Directory of Open Access Journals (Sweden)

    Juliana Aparecida Povh

    2013-07-01

    Full Text Available http://dx.doi.org/10.5007/2175-7925.2013v26n3p231 O objetivo deste artigo foi inventariar as plantas utilizadas na medicina popular pelos membros da comunidade rural de Santa Rita, no município de Ituiutaba - MG. A avaliação foi realizada por meio de entrevistas, com um questionário semiestruturado, e posterior coleta das plantas indicadas pelos informantes. Foram realizadas 47 entrevistas e 127 espécies foram listadas, pertencentes a 55 famílias de Angiospermas. Para obtenção dos dados quantitativos foi calculada a porcentagem de Concordância de Usos Principais (CUP de cada espécie; para identificar as indicações terapêuticas de maior importância, utilizou-se o Fator de Consenso dos Informantes (FCI. A CUP demonstrou que 5,5% das plantas citadas são amplamente utilizadas pela comunidade. As famílias botânicas predominantes foram Lamiaceae e Asteraceae, com 14 e 13 registros, respectivamente. A indicação de uso predominante envolveu, principalmente, afecções relacionadas a distúrbio emocional, conforme indicado pelo FCI. Salienta-se que 60,7% das plantas citadas neste artigo são espécies exóticas; desse modo, se faz necessário mais estudos para catalogar o conhecimento sobre as plantas medicinais nativas dessa região.

  2. Hurricane Rita surge data, southwestern Louisiana and southeastern Texas, September to November 2005

    Science.gov (United States)

    McGee, Benton D.; Goree, Burl B.; Tollett, Roland W.; Woodward, Brenda K.; Kress, Wade H.

    2006-01-01

    Pressure transducers and high-water marks were used to document the inland water levels related to storm surge generated by Hurricane Rita in southwestern Louisiana and southeastern Texas. On September 22-23, 2005, an experimental monitoring network consisting of 47 pressure transducers (sensors) was deployed at 33 sites over an area of about 4,000 square miles to record the timing, extent, and magnitude of inland hurricane storm surge and coastal flooding. Sensors were programmed to record date and time, temperature, and barometric or water pressure. Water pressure was corrected for changes in barometric pressure and salinity. Elevation surveys using global-positioning systems and differential levels were used to relate all storm-surge water-level data, reference marks, benchmarks, sensor measuring points, and high-water marks to the North American Vertical Datum of 1988 (NAVD 88). The resulting data indicated that storm-surge water levels over 14 feet above NAVD 88 occurred at three locations and rates of water-level rise greater than 5 feet per hour occurred at three locations near the Louisiana coast. Quality-assurance measures were used to assess the variability and accuracy of the water-level data recorded by the sensors. Water-level data from sensors were similar to data from co-located sensors, permanent U.S. Geological Survey streamgages, and water-surface elevations performed by field staff. Water-level data from sensors at selected locations were compared to corresponding high-water mark elevations. In general, the water-level data from sensors were similar to elevations of high quality high-water marks, while reporting consistently higher than elevations of lesser quality high-water marks.

  3. Post disaster resilience: Racially different correlates of depression symptoms among hurricane Katrina-Rita volunteers.

    Science.gov (United States)

    Nicdao, Ethel G; Noel, La Tonya; Ai, Amy L; Plummer, Carol; Groff, Sara

    2013-01-01

    The present analyses examined the differential risks of and protective factors against depressive symptoms of African American and Non-Hispanic White American student volunteers, respectively after Hurricanes Katrina and Rita (H-KR). A total sample of 554 student volunteers were recruited from mental health professional programs at five universities located in the Deep South, namely areas severely impacted by H-KR during fall semester 2005. The response rate was 91% (n = 505). African American respondents (n = 299) and Non-Hispanic White Americans (n = 206) completed the survey questionnaires. Respondents retrospectively provided information on peritraumatic emotional reactions and previous trauma that were recalled by H-KR and H-KR stressors. African American respondents reported higher levels of depressive symptoms (65.2%) than their Non-Hispanic White counterparts (34.8%). Hierarchical regression analyses revealed that disaster related stressors affected African Americans (p < 0.001), but not Non-Hispanic Whites. However, African Americans who experienced peritraumatic positive emotions had lower depression levels. Lower rates of recollection of prior traumas during H-KR were reported by African American respondents, whereas previous trauma recollections predicted symptoms among Non-Hispanic White Americans (p < 0.05). Exhibiting more optimism had lower depression levels among Non-Hispanic White Americans. Peritraumatic negative emotion was the only shared risk for depressive symptoms of both groups. Findings underscore racially different levels of depressive symptoms that may contribute to varying degrees of resilience among student volunteers. Future research and practice may address these racial differences by understanding the risk factors for depressive symptoms to develop appropriate interventions for racial groups, and cultivating the protective factors that contribute to resilience from traumatic experiences.

  4. Effects of hurricanes Katrina and Rita on Louisiana black bear habitat

    Science.gov (United States)

    Clark, Joseph D.; Murrow, Jennifer L.

    2012-01-01

    The Louisiana black bear (Ursus americanus luteolus) is comprised of 3 subpopulations, each being small, geographically isolated, and vulnerable to extinction. Hurricanes Katrina and Rita struck the Louisiana and Mississippi coasts in 2005, potentially altering habitat occupied by this federally threatened subspecies. We used data collected on radio-telemetered bears from 1993 to 1995 and pre-hurricane landscape data to develop a habitat model based on the Mahalanobis distance (D2) statistic. We then applied that model to post-hurricane landscape data where the telemetry data were collected (i.e., occupied study area) and where bear range expansion might occur (i.e., unoccupied study area) to quantify habitat loss or gain. The D2 model indicated that quality bear habitat was associated with areas of high mast-producing forest density, low water body density, and moderate forest patchiness. Cross-validation and testing on an independent data set in central Louisiana indicated that prediction and transferability of the model were good. Suitable bear habitat decreased from 348 to 345 km2 (0.9%) within the occupied study area and decreased from 34,383 to 33,891 km2 (1.4%) in the unoccupied study area following the hurricanes. Our analysis indicated that bear habitat was not significantly degraded by the hurricanes, although changes that could have occurred on a microhabitat level would be more difficult to detect at the resolution we used. We suggest that managers continue to monitor the possible long-term effects of these hurricanes (e.g., vegetation changes from flooding, introduction of toxic chemicals, or water quality changes).

  5. Assessing the Relationship Between Mental Distress and Tobacco Use in Post-Katrina and Rita Louisiana.

    Science.gov (United States)

    Mukherjee, Snigdha; Canterberry, Melanie; Yore, Jennifer B; Ledford, Edward Cannon; Carton, Thomas W

    2017-08-24

    The relationship between mental health status and smoking is complicated and often confounded by bi-directionality, yet most research on this relationship assumes exogeneity. The goal of this article is to implement an instrumental variable approach to (1) test the exogeneity assumption and (2) report on the association between mental health status and smoking post-disaster. This analysis utilizes the 2006 and 2007 Louisiana Behavioral Risk Factor Surveillance Survey to examine the link between mental distress and smoking in areas affected by Hurricanes Katrina and Rita. Residence in a hurricane-affected parish (county) was used as an instrumental variable for mental distress. Just over 22% of the sample resided in a hurricane-affected parish. Residents of hurricane-affected parishes were significantly more likely to report occasional and frequent mental distress. Residence in a hurricane-affected parish was not significantly associated with smoking status. With residence established as a salient instrumental variable for mental distress, the exogeneity assumption was tested and confirmed in this sample. A dose-response relationship existed between mental distress and smoking, with smoking prevalence increasing directly (and non-linearly) with mental distress. In this sample, the relationship between mental distress and smoking status was exogenous and followed a dose-response relationship, suggesting that the disasters did not result in an uptake of smoking initiation, but that the higher amounts of mental distress may lead to increased use among smokers. The findings suggest that tobacco control programs should devise unique strategies to address mentally distressed populations.

  6. Kinematic structure of convective-scale elements in the rainbands of Hurricanes Katrina and Rita (2005)

    Science.gov (United States)

    Hence, Deanna A.; Houze, Robert A.

    2008-08-01

    Airborne Doppler radar data collected during the Hurricane Rainband and Intensity Change Experiment (RAINEX) show the convective-scale air motions embedded in the principal rainbands of hurricanes Katrina and Rita. These embedded convective cells have overturning updrafts and low-level downdrafts (originating at 2-4 km) that enter the rainband on its radially outward side and cross over each other within the rainband as well as a strong downdraft emanating from upper levels (6+ km) on the radially inward side. These vertical motion structures repeat from one convective cell to another along each rainband. The resulting net vertical mass transport is upward in the upwind portion of the band and greatest in the middle sector of the principal rainband, where the updraft motions contribute generally to an increase of potential vorticity below the 3-4 km level. Because the convective cells in the middle sector are systematically located radially just inside the secondary horizontal wind maximum (SHWM), the local increase in vorticity implied by the convective mass transport is manifest locally as an increase in the strength of the SHWM at midlevels (˜4 km). The overturning updrafts of the convective cells tilt, stretch, and vertically transport vorticity such that the convergence of the vertical flux of vorticity strengthens the vorticity anomaly associated with the SHWM. This process could strengthen the SHWM by several meters per second per hour, and may explain how high wave number convective-scale features can influence a low wave number feature such as the principal rainband, and subsequently influence the primary vortex.

  7. Optimization of Nd: YAG Laser Marking of Alumina Ceramic Using RSM And ANN

    International Nuclear Information System (INIS)

    Peter, Josephine; Doloi, B.; Bhattacharyya, B.

    2011-01-01

    The present research papers deals with the artificial neural network (ANN) and the response surface methodology (RSM) based mathematical modeling and also an optimization analysis on marking characteristics on alumina ceramic. The experiments have been planned and carried out based on Design of Experiment (DOE). It also analyses the influence of the major laser marking process parameters and the optimal combination of laser marking process parametric setting has been obtained. The output of the RSM optimal data is validated through experimentation and ANN predictive model. A good agreement is observed between the results based on ANN predictive model and actual experimental observations.

  8. Biosorption of chromium (VI) from aqueous solutions and ANN modelling.

    Science.gov (United States)

    Nag, Soma; Mondal, Abhijit; Bar, Nirjhar; Das, Sudip Kumar

    2017-08-01

    The use of sustainable, green and biodegradable natural wastes for Cr(VI) detoxification from the contaminated wastewater is considered as a challenging issue. The present research is aimed to assess the effectiveness of seven different natural biomaterials, such as jackfruit leaf, mango leaf, onion peel, garlic peel, bamboo leaf, acid treated rubber leaf and coconut shell powder, for Cr(VI) eradication from aqueous solution by biosorption process. Characterizations were conducted using SEM, BET and FTIR spectroscopy. The effects of operating parameters, viz., pH, initial Cr(VI) ion concentration, adsorbent dosages, contact time and temperature on metal removal efficiency, were studied. The biosorption mechanism was described by the pseudo-second-order model and Langmuir isotherm model. The biosorption process was exothermic, spontaneous and chemical (except garlic peel) in nature. The sequence of adsorption capacity was mango leaf > jackfruit leaf > acid treated rubber leaf > onion peel > bamboo leaf > garlic peel > coconut shell with maximum Langmuir adsorption capacity of 35.7 mg g -1 for mango leaf. The treated effluent can be reused. Desorption study suggested effective reuse of the adsorbents up to three cycles, and safe disposal method of the used adsorbents suggested biodegradability and sustainability of the process by reapplication of the spent adsorbent and ultimately leading towards zero wastages. The performances of the adsorbents were verified with wastewater from electroplating industry. The scale-up study reported for industrial applications. ANN modelling using multilayer perception with gradient descent (GD) and Levenberg-Marquart (LM) algorithm had been successfully used for prediction of Cr(VI) removal efficiency. The study explores the undiscovered potential of the natural waste materials for sustainable existence of small and medium sector industries, especially in the third world countries by protecting the environment by eco-innovation.

  9. Review of Artificial Neural Networks (ANN) applied to corrosion monitoring

    International Nuclear Information System (INIS)

    Mabbutt, S; Picton, P; Shaw, P; Black, S

    2012-01-01

    The assessment of corrosion within an engineering system often forms an important aspect of condition monitoring but it is a parameter that is inherently difficult to measure and predict. The electrochemical nature of the corrosion process allows precise measurements to be made. Advances in instruments, techniques and software have resulted in devices that can gather data and perform various analysis routines that provide parameters to identify corrosion type and corrosion rate. Although corrosion rates are important they are only useful where general or uniform corrosion dominates. However, pitting, inter-granular corrosion and environmentally assisted cracking (stress corrosion) are examples of corrosion mechanisms that can be dangerous and virtually invisible to the naked eye. Electrochemical noise (EN) monitoring is a very useful technique for detecting these types of corrosion and it is the only non-invasive electrochemical corrosion monitoring technique commonly available. Modern instrumentation is extremely sensitive to changes in the system and new experimental configurations for gathering EN data have been proven. In this paper the identification of localised corrosion by different data analysis routines has been reviewed. In particular the application of Artificial Neural Network (ANN) analysis to corrosion data is of key interest. In most instances data needs to be used with conventional theory to obtain meaningful information and relies on expert interpretation. Recently work has been carried out using artificial neural networks to investigate various types of corrosion data in attempts to predict corrosion behaviour with some success. This work aims to extend this earlier work to identify reliable electrochemical indicators of localised corrosion onset and propagation stages.

  10. Optimum coagulant forecasting by modeling jar test experiments using ANNs

    Science.gov (United States)

    Haghiri, Sadaf; Daghighi, Amin; Moharramzadeh, Sina

    2018-01-01

    Currently, the proper utilization of water treatment plants and optimizing their use is of particular importance. Coagulation and flocculation in water treatment are the common ways through which the use of coagulants leads to instability of particles and the formation of larger and heavier particles, resulting in improvement of sedimentation and filtration processes. Determination of the optimum dose of such a coagulant is of particular significance. A high dose, in addition to adding costs, can cause the sediment to remain in the filtrate, a dangerous condition according to the standards, while a sub-adequate dose of coagulants can result in the reducing the required quality and acceptable performance of the coagulation process. Although jar tests are used for testing coagulants, such experiments face many constraints with respect to evaluating the results produced by sudden changes in input water because of their significant costs, long time requirements, and complex relationships among the many factors (turbidity, temperature, pH, alkalinity, etc.) that can influence the efficiency of coagulant and test results. Modeling can be used to overcome these limitations; in this research study, an artificial neural network (ANN) multi-layer perceptron (MLP) with one hidden layer has been used for modeling the jar test to determine the dosage level of used coagulant in water treatment processes. The data contained in this research have been obtained from the drinking water treatment plant located in Ardabil province in Iran. To evaluate the performance of the model, the mean squared error (MSE) and correlation coefficient (R2) parameters have been used. The obtained values are within an acceptable range that demonstrates the high accuracy of the models with respect to the estimation of water-quality characteristics and the optimal dosages of coagulants; so using these models will allow operators to not only reduce costs and time taken to perform experimental jar tests

  11. Hurricane Rita and the destruction of Holly Beach, Louisiana: Why the chenier plain is vulnerable to storms

    Science.gov (United States)

    Sallenger, A.H.; Wright, C.W.; Doran, K.; Guy, K.; Morgan, K.

    2009-01-01

    Hurricane Rita devastated gulf-front communities along the western Louisiana coast in 2005. LIDAR (light detection and ranging) topographic surveys and aerial photography collected before and after the storm showed the loss of every structure within the community of Holly Beach. Average shoreline change along western Louisiana's 140-km-long impacted shore was -23.3 ?? 30.1 m of erosion, although shoreline change in Holly Beach was substantially less, and erosion was not pervasive where the structures were lost. Before the storm, peak elevations of the dunes, or berms in the absence of dunes, along the impacted shore averaged 1.6 m. The storm surge, which reached 3.5 m just east of Holly Beach, completely inundated the beach systems along the impacted western Louisiana shore. The high surge potential and low land elevations make this coast extremely vulnerable to hurricanes. In fact, most of the western Louisiana shore impacted by Rita will be completely inundated by the storm surge of a worst-case Saffi r-Simpson category 1 hurricane. All of this shore will be inundated by worst-case category 2-5 storms. ?? 2009 The Geological Society of America.

  12. Nonlinear terms in storm surge predictions: Effect of tide and shelf geometry with case study from Hurricane Rita

    Science.gov (United States)

    Rego, JoãO. L.; Li, Chunyan

    2010-06-01

    This study applied the finite volume coastal ocean model (FVCOM) to the storm surge induced by Hurricane Rita along the Louisiana-Texas coast. The model was calibrated for tides and validated with observed water levels. Peak water levels were shown to be lower than expected for a landfall at high tide. For low- and high-tide landfalls, nonlinear effects due to tide-surge coupling were constructive and destructive to total storm tide, respectively, and their magnitude reached up to 70% of the tidal amplitude in the Rita application. Tide-surge interaction was further examined using a standard hurricane under idealized scenarios to evaluate the effects of various shelf geometries, tides, and landfall timings (relative to tide). Nonlinearity was important between landfall position and locations within 2.5 × radius of maximum winds. On an idealized wide continental shelf, nonlinear effects reached up to 80% of the tidal amplitude with an S2 tide and up to 47% with a K1 tide. Increasing average depths by 4 m reduced nonlinear effects to 41% of the tidal amplitude; increasing the slope by a factor of 3 produced nonlinearities of just 26% of tide (both with a K1 tide). The nonlinear effect was greatest for landfalls at low tide, followed by landfalls at high tide and then by landfalls at midebb or midflood.

  13. Mammals of medium and large size in Santa Rita do Sapucaí, Minas Gerais, southeastern Brazil

    Directory of Open Access Journals (Sweden)

    Eduardo, A. A.

    2009-01-01

    Full Text Available The diversity of Brazilian vertebrates is regarded among the highest in the world. However, the biologicaldiversity is still mostly unknown and a good part of it is seriously threatened by human activities. This study aimed toinventory the medium and large size mammals present in the Reserva Biológica de Santa Rita do Sapucaí, an Atlanticforest reserve located in Santa Rita do Sapucaí, southeastern Brazil. Sand-plots, photographic traps and searches foranimal tracks on pre-existent trails in the area, were carried out once every two months between May 2006 andFebruary 2007. The sand-plots and tracks were inspected during five consecutive days per sampling. We obtained 108records of 15 species, mostly of carnivorans. Two confirmed species are threatened with extinction in Brazil (Callithrixaurita and Leopardus pardalis. The results suggest that the sampled reserve has high species richness and plays animportant role in conservation of mammals in this landscape, including species threatened with extinction.

  14. Santa Rita Experimental Range: 100 years (1903 to 2003) of accomplishments and contributions; conference proceedings; 2003 October 30-November 1; Tucson, AZ

    Science.gov (United States)

    Mitchel P. McClaran; Peter F. Ffolliott; Carleton B. Edminster

    2003-01-01

    The purpose of this conference was to celebrate the 100 years of accomplishments and contributions of the Santa Rita Experimental Range, the longest continuously operating research area dedicated to the sustainable management of North American rangelands. The conference consisted of one-and-a-half days of invited synthesis papers and contributed poster presentations...

  15. Impacts of Hurricane Rita on the beaches of western Louisiana: Chapter 5D in Science and the storms-the USGS response to the hurricanes of 2005

    Science.gov (United States)

    Stockdon, Hilary F.; Fauver, Laura A.; Sallenger,, Asbury H.; Wright, C. Wayne

    2007-01-01

    Hurricane Rita made landfall as a category 3 storm in western Louisiana in late September 2005, 1 month following Hurricane Katrina's devastating landfall in the eastern part of the State. Large waves and storm surge inundated the lowelevation coastline, destroying many communities and causing extensive coastal change including beach, dune, and marsh erosion.

  16. Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents

    NARCIS (Netherlands)

    Michaelis, M.; Rothweiler, F.; Agha, B.; Barth, S.; Voges, Y.; Loeschmann, N.; von Deimling, A.; Breitling, R.; Doerr, H. Wilhelm; Roedel, F.; Speidel, D.; Cinatl, J.; Cinatl Jr., J.; Stephanou, A.

    Adaptation of wild-type p53 expressing UKF-NB-3 cancer cells to the murine double minute 2 inhibitor nutlin-3 causes de novo p53 mutations at high frequency (13/20) and multi-drug resistance. Here, we show that the same cells respond very differently when adapted to RITA, a drug that, like nutlin-3,

  17. Hurricanes Katrina and Rita: Temporary Emergency Impact Aid Provided Education Support for Displaced Students. Report to the Congressional Requesters. GAO-11-839

    Science.gov (United States)

    Scott, George A.

    2011-01-01

    In August and September 2005, Hurricanes Katrina and Rita devastated large portions of the U.S. Gulf Coast, resulting in nearly 2,000 deaths and severe damage to 305,000 houses and apartments. Thousands of families relocated to communities throughout the United States and enrolled their children in local public or private schools. Some families…

  18. Prediction of Splitting Tensile Strength of Concrete Containing Zeolite and Diatomite by ANN

    Directory of Open Access Journals (Sweden)

    E. Gülbandılar

    2017-01-01

    Full Text Available This study was designed to investigate with two different artificial neural network (ANN prediction model for the behavior of concrete containing zeolite and diatomite. For purpose of constructing this model, 7 different mixes with 63 specimens of the 28, 56 and 90 days splitting tensile strength experimental results of concrete containing zeolite, diatomite, both zeolite and diatomite used in training and testing for ANN systems was gathered from the tests. The data used in the ANN models are arranged in a format of seven input parameters that cover the age of samples, Portland cement, zeolite, diatomite, aggregate, water and hyper plasticizer and an output parameter which is splitting tensile strength of concrete. In the model, the training and testing results have shown that two different ANN systems have strong potential as a feasible tool for predicting 28, 56 and 90 days the splitting tensile strength of concrete containing zeolite and diatomite.

  19. Igal mõisal on oma lugu / Mari-Ann Remmel

    Index Scriptorium Estoniae

    Remmel, Mari-Ann

    2008-01-01

    Kirjastuselt "Tänapäev" ilmus raamat "Mõisalegendid. Harjumaa", koostaja Mari-Ann Remmel, kujundaja Angelika Schneider. Kogumik sisaldab ka ajaloolist ning genealoogilist teavet mõisahoonete ning -omanike kohta

  20. Enamik Mõtteloo Sihtkapitali rahast kasvab USA aktsiates / Mart Trummal ; interv. Anne Oja

    Index Scriptorium Estoniae

    Trummal, Mart

    2006-01-01

    Intervjuu Eesti Mõtteloo Sihtkapitali juhi Mart Trummaliga. Tabel: Mõtteloo Sihtkapitali vara on USA-s noteeritud indeksifondides; Investeeringud Eesti aktsiatesse. Diagramm: Finantsinvesteeringute maht. Vt. samas: Anne Oja. Dividendisaajate esirinnas. Kommenteerib Annika Matson

  1. Damage level prediction of non-reshaped berm breakwater using ANN, SVM and ANFIS models

    Digital Repository Service at National Institute of Oceanography (India)

    Mandal, S.; SubbaRao; Harish, N.; Lokesha

    Marine Structures Laboratory, Department of Applied Mechanics and Hydraulics, NITK, Surathkal, India. Soft computing techniques like Artificial Neural Network (ANN), Support Vector Machine (SVM) and Adaptive Neuro Fuzzy Inference system (ANFIS) models...

  2. Mart ja Mari-Ann Susi taotlevad omanikena Concordia pankrotti / Andri Maimets

    Index Scriptorium Estoniae

    Maimets, Andri, 1979-

    2003-01-01

    Concordia Ülikooli rektor Mart Susi esitas kohtule avalduse, milles taotleb ülikooli pidanud Concordia Varahalduse OÜ pankroti väljakuulutamist. Vt. samas: Mari-Ann Susi õigustas ülikooli raha kasutamist

  3. 2006 Maryland Department of Natural Resources Lidar: Caroline, Kent and Queen Anne Counties

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Maryland Department of Natural Resources requested the collection of LIDAR data over Kent, Queen Anne and Caroline Counties, MD. In response, EarthData acquired the...

  4. Thesis defence: Anneli Baran Possibilities for studying semantics in phraseology / Outi Lauhakangas

    Index Scriptorium Estoniae

    Lauhakangas, Outi

    2011-01-01

    15. märtsil 2011 kaitses Anneli Baran Tartu Ülikooli kultuuriteaduste ja kunstide instituudis doktoriväitekirja Fraseologismide semantika uurimisvõimalused, juhendaja Arvo Krikmann (Eesti Kirjandusmuuseum), oponent dr Outi Lauhakangas (Soome Kirjanduse Selts)

  5. Tallinna Ülikool / Leif Kalev, Anneli Leinpere, Tiit Land, Alessandro Centonze, Hannes Palang, Liis Kelberg

    Index Scriptorium Estoniae

    2008-01-01

    Ülikooli ja seal õpetatavaid erialasid tutvustavad dotsent Leif Kalev, kunstimagistrant Anneli Leinpere, professor Tiit Land, välisüliõpilane Milanost Alessandro Centonze, vanemteadur Hannes Palang ning kirjaliku tõlke magistrant Liis Kelberg

  6. Benthic Habitat Mapping - Dry Tortugas RoxAnn Acoustic Sensor Data Points

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — During April 2001 RoxAnn single-beam acoustic surveys were conducted at the North Unit of the Tortugas Ecological Reserve, Florida. Thirteen transects associated...

  7. ANN based optimization of a solar assisted hybrid cooling system in Turkey

    Energy Technology Data Exchange (ETDEWEB)

    Ozgur, Arif; Yetik, Ozge; Arslan, Oguz [Mechanical Eng. Dept., Engineering Faculty, Dumlupinar University (Turkey)], email: maozgur@dpu.edu.tr, email: ozgeyetik@dpu.edu.tr, email: oarslan@dpu.edu.tr

    2011-07-01

    This study achieved optimization of a solar assisted hybrid cooling system with refrigerants such as R717, R141b, R134a and R123 using an artificial neural network (ANN) model based on average total solar radiation, ambient temperature, generator temperature, condenser temperature, intercooler temperature and fluid types. ANN is a new tool; it works rapidly and can thus be a solution for design and optimization of complex power cycles. A unique flexible ANN algorithm was introduced to evaluate the solar ejector cooling systems because of the nonlinearity of neural networks. The conclusion was that the best COPs value obtained with the ANN is 1.35 and COPc is 3.03 when the average total solar radiation, ambient temperature, generator temperature, condenser temperature, intercooler temperature and algorithm are respectively 674.72 W/m2, 17.9, 80, 15 and 13 degree celsius and LM with 14 neurons in single hidden layer, for R717.

  8. 78 FR 65380 - Notice of Inventory Completion: University of Michigan, Ann Arbor, MI

    Science.gov (United States)

    2013-10-31

    ... the University of Michigan, Ann Arbor, MI. The human remains were removed from Alpena, Isabella, Grand... removed from the Devil River Mound site (20AL1) in Alpena County, MI. A resident of Ossineke, MI...

  9. Evaluation Of The Advanced Operating System Of The Ann Arbor Transportation Authority : AATA Web Survey

    Science.gov (United States)

    1999-01-01

    During 1997, visitors to the Ann Arbor (Michigan) Transportation Authority's worldwide web site were invited to complete an electronic questionnaire about their experience with the site. Eighty surveys were collected, representing a non-scientific se...

  10. Artificial Neural Networks (ANNs for flood forecasting at Dongola Station in the River Nile, Sudan

    Directory of Open Access Journals (Sweden)

    Sulafa Hag Elsafi

    2014-09-01

    Full Text Available Heavy seasonal rains cause the River Nile in Sudan to overflow and flood the surroundings areas. The floods destroy houses, crops, roads, and basic infrastructure, resulting in the displacement of people. This study aimed to forecast the River Nile flow at Dongola Station in Sudan using an Artificial Neural Network (ANN as a modeling tool and validated the accuracy of the model against actual flow. The ANN model was formulated to simulate flows at a certain location in the river reach, based on flow at upstream locations. Different procedures were applied to predict flooding by the ANN. Readings from stations along the Blue Nile, White Nile, Main Nile, and River Atbara between 1965 and 2003 were used to predict the likelihood of flooding at Dongola Station. The analysis indicated that the ANN provides a reliable means of detecting the flood hazard in the River Nile.

  11. 10 Stewart 03.pmd

    African Journals Online (AJOL)

    Owner

    2010-07-29

    Jul 29, 2010 ... have a tree growing in their heads, but the brain itself is much more a grass than a tree. .... point for further research or learning since Mesopotamian times. ..... frozen in its incomplete form – via the Wayback machine. .... wiki was a decision to consider a broader range of possible ways for participants to.

  12. Jeb Stewart's Dilemma

    Science.gov (United States)

    Cedo, Kelli M.; Dickerson, William E.

    2010-01-01

    This case study creates a dilemma that many school districts face. Public education is under-funded. Principals are expected to be the instructional leaders and are held accountable for student achievement. Is it appropriate then for public schools to have local businesses as benefactors when teaching personnel are involved? The conflict between…

  13. ANN-based wavelet analysis for predicting electrical signal from photovoltaic power supply system

    Energy Technology Data Exchange (ETDEWEB)

    Mellit, A. [Medea Univ., Medea (Algeria). Inst. of Science Engineering, Dept. of Electronics

    2007-07-01

    This study was conducted to predict different electrical signals from a photovoltaic power supply system (PVPS) using an artificial neural networks (ANN) with wavelet analysis. It involved the creation of a database of electrical signals (PV-generator current, voltage, battery current voltage, regulator current and voltage) obtained from an experimental PVPS system installed in the south of Algeria. The potential applications were for sizing and analyzing the performance of PVPS systems; control of maximum power point tracker (MPPT) in order to deliver the maximum energy from the PV-array; prediction of the optimal configuration (PV-array and battery sizing) of PVPS systems; expert configuration of PV-systems; faults diagnosis; supervision; and, control and monitoring. First, based on the wavelet analysis each electrical signal was mapped in several time frequency domains. The PV-system was then divided into 3-subsystems corresponding to ANN-PV generator model, ANN-battery model, and ANN-regulator model. An example of day-by-day prediction for each electrical signal was presented. The results of the proposed approach were in good agreement with experimental results. In addition, the accuracy of the proposed approach was more satisfactory when only ANN was used. It was concluded that this methodology offers the possibility of developing a new expert configuration of PVPS by implementing the soft computing ANN-wavelet program with a digital signal processing (DSP) circuit. 26 refs., 1 tab., 5 figs.

  14. Prediction of Film Cooling Effectiveness on a Gas Turbine Blade Leading Edge Using ANN and CFD

    Science.gov (United States)

    Dávalos, J. O.; García, J. C.; Urquiza, G.; Huicochea, A.; De Santiago, O.

    2018-05-01

    In this work, the area-averaged film cooling effectiveness (AAFCE) on a gas turbine blade leading edge was predicted by employing an artificial neural network (ANN) using as input variables: hole diameter, injection angle, blowing ratio, hole and columns pitch. The database used to train the network was built using computational fluid dynamics (CFD) based on a two level full factorial design of experiments. The CFD numerical model was validated with an experimental rig, where a first stage blade of a gas turbine was represented by a cylindrical specimen. The ANN architecture was composed of three layers with four neurons in hidden layer and Levenberg-Marquardt was selected as ANN optimization algorithm. The AAFCE was successfully predicted by the ANN with a regression coefficient R2<0.99 and a root mean square error RMSE=0.0038. The ANN weight coefficients were used to estimate the relative importance of the input parameters. Blowing ratio was the most influential parameter with relative importance of 40.36 % followed by hole diameter. Additionally, by using the ANN model, the relationship between input parameters was analyzed.

  15. The Walnut Gulch - Santa Rita Wildland Watershed-Scale LTAR Sites

    Science.gov (United States)

    Goodrich, D. C.; Heilman, P.; Scott, R. L.; Nearing, M. A.; Moran, M. S.; Nichols, M.; Vivoni, E. R.; Archer, S. R.; Biederman, J.; Naito, A. T.

    2015-12-01

    The 150 km2 Walnut Gulch Experimental Watershed (WGEW), a Long-Term Agroecosystem Research (LTAR) site, near Tombstone, Arizona was established in 1953 by the USDA-ARS Southwest Watershed Research Center in Tucson. It is one of the most intensively instrumented semiarid experimental watersheds in the world with elevation ranging from 1220 to 1950 m with mean annual temperature and precipitation equal to 17.7°C and 312 mm. Desert shrubs dominate the lower two thirds of the watershed and grasses the upper third. Spatial variation in precipitation is measured with a network of 88 weighing-type recording rain gauges. Surface runoff is quantified over a range of scales (0.002 to 0.06 km2) to characterize interactions between rainfall intensity, soils and vegetation at nine sub-watersheds. Channel network processes and rainfall spatial variability are studied using 11 nested watersheds (2 to 150 km2). Sediment from the small sub-watersheds is sampled. Meteorological, soil moisture and temperature, and energy/water/CO2 flux measurements are made within two vegetation/soil complexes. Parallel investigations dating back to 1974 have also been conducted on eight small experimental watersheds at the Santa Rita Experimental Range (SRER) 80 km west of Walnut Gulch. In contrast to the creosote bush-grass WGEW, the mesquite-grass SRER is publicly owned, which ensures control and consistent reporting of management for research purposes. A key LTAR objective is to contrast a "business as usual" to an alternate management strategy presumed to have the potential of significantly improving forage and livestock production and diversification of ecosystem services. Consequently, a new ARS-U. of Arizona-Arizona State U. partnership will assess the watershed-scale impacts of brush management, a common land use practice typically applied in conjunction with livestock grazing, on a suite of ecosystem services at the SRER including provisioning (forage production, water yield), supporting

  16. Regeneration of coastal marsh vegetation impacted by hurricanes Katrina and Rita

    Science.gov (United States)

    Middleton, B.A.

    2009-01-01

    The dynamics of plant regeneration via seed and vegetative spread in coastal wetlands dictate the nature of community reassembly that takes place after hurricanes or sea level rise. The objectives of my project were to evaluate the potential effects of saltwater intrusion and flooding of Hurricanes Katrina and Rita on seedling regeneration in coastal wetlands of the Gulf Coast. Specifically I tested hypotheses to determine for species in fresh, brackish and salt marshes of the Gulf Coast if 1) the pattern of seed germination and seedling recruitment differed with distance from the shoreline, and 2) seed germination and seedling recruitment for various species were reduced in higher levels of water depth and salinity. Regarding Hypothesis 1, seedling densities increased with distance from the shoreline in fresh and brackish water marshes while decreasing with distance from the shoreline in salt marshes. Also to test Hypothesis 1, I used a greenhouse seed bank assay to examine seed germination from seed banks collected at distances from the shoreline in response to various water depths and salinity levels using a nested factorial design. For all marsh types, the influence of water level and salinity on seed germination shifted with distance from the shoreline (i.e., three way interaction of the main effects of distance nested within site, water depth, and salinity). Data from the seed bank assay were also used to test Hypothesis 2. The regeneration of species from fresh, brackish, and salt marshes were reduced in conditions of high salinity and/or water, so that following hurricanes or sea level rise, seedling regeneration could be reduced. Among the species of these coastal marshes, there was some flexibility of response, so that at least some species were able to germinate in either high or low salinity. Salt marshes had a few fresher marsh species in the seed bank that would not germinate without a period of fresh water input (e.g., Sagittaria lancifolia) as well

  17. EAARL coastal topography and imagery–Western Louisiana, post-Hurricane Rita, 2005: First surface

    Science.gov (United States)

    Bonisteel-Cormier, Jamie M.; Wright, Wayne C.; Fredericks, Alexandra M.; Klipp, Emily S.; Nagle, Doug B.; Sallenger, Asbury H.; Brock, John C.

    2013-01-01

    These remotely sensed, geographically referenced color-infrared (CIR) imagery and elevation measurements of lidar-derived first-surface (FS) topography datasets were produced by the U.S. Geological Survey (USGS), St. Petersburg Coastal and Marine Science Center, St. Petersburg, Florida, and the National Aeronautics and Space Administration (NASA), Wallops Flight Facility, Virginia. This project provides highly detailed and accurate datasets of a portion of the Louisiana coastline beachface, acquired post-Hurricane Rita on September 27-28 and October 2, 2005. The datasets are made available for use as a management tool to research scientists and natural-resource managers. An innovative airborne lidar instrument originally developed at the National Aeronautics and Space Administration (NASA) Wallops Flight Facility, and known as the Experimental Advanced Airborne Research Lidar (EAARL), was used during data acquisition. The EAARL system is a raster-scanning, waveform-resolving, green-wavelength (532-nanometer) lidar designed to map near-shore bathymetry, topography, and vegetation structure simultaneously. The EAARL sensor suite includes the raster-scanning, water-penetrating full-waveform adaptive lidar, a down-looking red-green-blue (RGB) digital camera, a high-resolution multispectral color-infrared (CIR) camera, two precision dual-frequency kinematic carrier-phase GPS receivers, and an integrated miniature digital inertial measurement unit, which provide for sub-meter georeferencing of each laser sample. The nominal EAARL platform is a twin-engine Cessna 310 aircraft, but the instrument may be deployed on a range of light aircraft. A single pilot, a lidar operator, and a data analyst constitute the crew for most survey operations. This sensor has the potential to make significant contributions in measuring sub-aerial and submarine coastal topography within cross-environmental surveys. Elevation measurements were collected over the survey area using the EAARL

  18. Liisingulepingu ennetähtaegsest lõppemisest tulenevad nõuded liisinguandja poolt liisinguvõtja vastu esitatava pankrotiavalduse alusena : [bakalaureusetöö] / Eliza Lainela ; Tartu Ülikool, õigusteaduskond ; juhendajad: Rita Malken, Mari Ann S

    Index Scriptorium Estoniae

    Lainela, Eliza

    2009-01-01

    Pankrotiavalduse esitamise eeldustest ning probleemidest liisingulepingu puhul, liisingulepingu ennetähtaegsest lõpetamisest tulenevatest nõuetest juhul kui liisinguese on müüdud või siis müümata

  19. Satellite Assessment of Bio-Optical Properties of Northern Gulf of Mexico Coastal Waters Following Hurricanes Katrina and Rita.

    Science.gov (United States)

    Lohrenz, Steven E; Cai, Wei-Jun; Chen, Xiaogang; Tuel, Merritt

    2008-07-10

    The impacts of major tropical storms events on coastal waters include sediment resuspension, intense water column mixing, and increased delivery of terrestrial materials into coastal waters. We examined satellite imagery acquired by the Moderate Resolution Imaging Spectroradiometer (MODIS) ocean color sensor aboard the Aqua spacecraft following two major hurricane events: Hurricane Katrina, which made landfall on 29 August 2005, and Hurricane Rita, which made landfall on 24 September. MODIS Aqua true color imagery revealed high turbidity levels in shelf waters immediately following the storms indicative of intense resuspension. However, imagery following the landfall of Katrina showed relatively rapid return of shelf water mass properties to pre-storm conditions. Indeed, MODIS Aqua-derived estimates of diffuse attenuation at 490 nm (K_490) and chlorophyll (chlor_a) from mid-August prior to the landfall of Hurricane Katrina were comparable to those observed in mid-September following the storm. Regions of elevated K_490 and chlor_a were evident in offshore waters and appeared to be associated with cyclonic circulation (cold-core eddies) identified on the basis of sea surface height anomaly (SSHA). Imagery acquired shortly after Hurricane Rita made landfall showed increased water column turbidity extending over a large area of the shelf off Louisiana and Texas, consistent with intense resuspension and sediment disturbance. An interannual comparison of satellite-derived estimates of K_490 for late September and early October revealed relatively lower levels in 2005, compared to the mean for the prior three years, in the vicinity of the Mississippi River birdfoot delta. In contrast, levels above the previous three year mean were observed off Texas and Louisiana 7-10 d after the passage of Rita. The lower values of K_490 near the delta could be attributed to relatively low river discharge during the preceding months of the 2005 season. The elevated levels off Texas and

  20. RITA--Registry of Industrial Toxicology Animal data: the application of historical control data for Leydig cell tumors in rats.

    Science.gov (United States)

    Nolte, Thomas; Rittinghausen, Susanne; Kellner, Rupert; Karbe, Eberhard; Kittel, Birgit; Rinke, Matthias; Deschl, Ulrich

    2011-11-01

    Historical data for Leydig cell tumors from untreated or vehicle treated rats from carcinogenicity studies collected in the RITA database are presented. Examples are given for analyses of these data for dependency on variables considered to be of possible influence on the spontaneous incidence of Leydig cell tumors. In the 7453 male rats available for analysis, only one case of a Leydig cell carcinoma was identified. The incidence of Leydig cell adenomas differed markedly between strains. High incidences of close to 100% have been found in F344 rats, while the mean incidence was 4.2% in Sprague-Dawley rats and 13.7% in Wistar rats. Incidences in Wistar rats were highly variable, primarily caused by different sources of animals. Mean incidences per breeder varied from 2.8 to 39.9%. Analyses for the dependency on further parameters have been performed in Wistar rats. In breeders G and I, the Leydig cell tumor incidence decreased over the observation period and with increasing mean terminal body weight. The incidence of Leydig cell tumors increased with mean age at necropsy and was higher in studies with dietary admixture compared to gavage studies. These parameters had no effect on Leydig cell tumor incidence in breeders A and B. Animals from almost all breeders had a considerably higher mean age at necropsy when bearing a Leydig cell adenoma than animals without a Leydig cell adenoma. Studies with longitudinal trimming of the testes had a higher incidence than studies with transverse trimming. The observed dependencies and breeder differences are discussed and explanations are given. Consequences for the use of historical control data are outlined. With the retrospective analyses presented here we were able to confirm the published features of Leydig cell adenomas and carcinomas. This indicates that the RITA database is a valuable tool for analyses of tumors for their biological features. Furthermore, it demonstrates that the RITA database is highly beneficial for

  1. Satellite Assessment of Bio-Optical Properties of Northern Gulf of Mexico Coastal Waters Following Hurricanes Katrina and Rita

    Directory of Open Access Journals (Sweden)

    Merritt Tuel

    2008-07-01

    Full Text Available The impacts of major tropical storms events on coastal waters include sediment resuspension, intense water column mixing, and increased delivery of terrestrial materials into coastal waters. We examined satellite imagery acquired by the Moderate Resolution Imaging Spectroradiometer (MODIS ocean color sensor aboard the Aqua spacecraft following two major hurricane events: Hurricane Katrina, which made landfall on 29 August 2005, and Hurricane Rita, which made landfall on 24 September. MODIS Aqua true color imagery revealed high turbidity levels in shelf waters immediately following the storms indicative of intense resuspension. However, imagery following the landfall of Katrina showed relatively rapid return of shelf water mass properties to pre-storm conditions. Indeed, MODIS Aqua-derived estimates of diffuse attenuation at 490 nm (K_490 and chlorophyll (chlor_a from mid-August prior to the landfall of Hurricane Katrina were comparable to those observed in mid-September following the storm. Regions of elevated K_490 and chlor_a were evident in offshore waters and appeared to be associated with cyclonic circulation (cold-core eddies identified on the basis of sea surface height anomaly (SSHA. Imagery acquired shortly after Hurricane Rita made landfall showed increased water column turbidity extending over a large area of the shelf off Louisiana and Texas, consistent with intense resuspension and sediment disturbance. An interannual comparison of satellite-derived estimates of K_490 for late September and early October revealed relatively lower levels in 2005, compared to the mean for the prior three years, in the vicinity of the Mississippi River birdfoot delta. In contrast, levels above the previous three year mean were observed off Texas and Louisiana 7-10 d after the passage of Rita. The lower values of K_490 near the delta could be attributed to relatively low river discharge during the preceding months of the 2005 season. The elevated levels

  2. Novel Formulation of Adaptive MPC as EKF Using ANN Model: Multiproduct Semibatch Polymerization Reactor Case Study.

    Science.gov (United States)

    Kamesh, Reddi; Rani, Kalipatnapu Yamuna

    2017-12-01

    In this paper, a novel formulation for nonlinear model predictive control (MPC) has been proposed incorporating the extended Kalman filter (EKF) control concept using a purely data-driven artificial neural network (ANN) model based on measurements for supervisory control. The proposed scheme consists of two modules focusing on online parameter estimation based on past measurements and control estimation over control horizon based on minimizing the deviation of model output predictions from set points along the prediction horizon. An industrial case study for temperature control of a multiproduct semibatch polymerization reactor posed as a challenge problem has been considered as a test bed to apply the proposed ANN-EKFMPC strategy at supervisory level as a cascade control configuration along with proportional integral controller [ANN-EKFMPC with PI (ANN-EKFMPC-PI)]. The proposed approach is formulated incorporating all aspects of MPC including move suppression factor for control effort minimization and constraint-handling capability including terminal constraints. The nominal stability analysis and offset-free tracking capabilities of the proposed controller are proved. Its performance is evaluated by comparison with a standard MPC-based cascade control approach using the same adaptive ANN model. The ANN-EKFMPC-PI control configuration has shown better controller performance in terms of temperature tracking, smoother input profiles, as well as constraint-handling ability compared with the ANN-MPC with PI approach for two products in summer and winter. The proposed scheme is found to be versatile although it is based on a purely data-driven model with online parameter estimation.

  3. Dual targeting of wild-type and mutant p53 by small molecule RITA results in the inhibition of N-Myc and key survival oncogenes and kills neuroblastoma cells in vivo and in vitro.

    Science.gov (United States)

    Burmakin, Mikhail; Shi, Yao; Hedström, Elisabeth; Kogner, Per; Selivanova, Galina

    2013-09-15

    Restoration of the p53 function in tumors is a promising therapeutic strategy due to the high potential of p53 as tumor suppressor and the fact that established tumors depend on p53 inactivation for their survival. Here, we addressed the question whether small molecule RITA can reactivate p53 in neuroblastoma and suppress the growth of neuroblastoma cells in vitro and in vivo. The ability of RITA to inhibit growth and to induce apoptosis was shown in seven neuroblastoma cell lines. Mechanistic studies were carried out to determine the p53 dependence and the molecular mechanism of RITA-induced apoptosis in neuroblastoma, using cell viability assays, RNAi silencing, co-immunoprecipitation, qPCR, and Western blotting analysis. In vivo experiments were conducted to study the effect of RITA on human neuroblastoma xenografts in mice. RITA induced p53-dependent apoptosis in a set of seven neuroblastoma cell lines, carrying wild-type or mutant p53; it activated p53 and triggered the expression of proapoptotic p53 target genes. Importantly, p53 activated by RITA inhibited several key oncogenes that are high-priority targets for pharmacologic anticancer strategies in neuroblastoma, including N-Myc, Aurora kinase, Mcl-1, Bcl-2, Wip-1, MDM2, and MDMX. Moreover, RITA had a strong antitumor effect in vivo. Reactivation of wild-type and mutant p53 resulting in the induction of proapoptotic factors along with ablation of key oncogenes by compounds such as RITA may be a highly effective strategy to treat neuroblastoma. ©2013 AACR.

  4. The effects of Hurricanes Katrina and Rita on seabed polycyclic aromatic hydrocarbon dynamics in the Gulf of Mexico.

    Science.gov (United States)

    Mitra, Siddhartha; Lalicata, Joseph J; Allison, Mead A; Dellapenna, Timothy M

    2009-06-01

    To assess the extent to which Hurricanes Katrina and Rita affected polycyclic aromatic hydrocarbons (PAH) in the Gulf of Mexico (GOM), sediment cores were analyzed in late 2005 from: a shallow shelf, a deeper shelf, and a marsh station. Sediment geochronology, fabric, and geochemistry show that the 2005 storms deposited approximately 10cm of sediment to the surface of a core at 5-12A. Bulk carbon geochemistry and PAH isomers in this top layer suggest that the source of sediment to the top portion of core 5-12A was from a relatively more marine area. Particulate PAHs in the marsh core (04M) appeared unaffected by the storms while sediments in the core from Station 5-1B (deeper shelf) were affected minimally (some possible storm-derived deposition). Substantial amounts of PAH-laden particles may have been displaced from the seabed in shallow areas of the water column in the GOM by these 2005 storms.

  5. Recent infection testing algorithm (RITA) applied to new HIV diagnoses in England, Wales and Northern Ireland, 2009 to 2011.

    Science.gov (United States)

    Aghaizu, A; Murphy, G; Tosswill, J; DeAngelis, D; Charlett, A; Gill, O N; Ward, H; Lattimore, S; Simmons, Rd; Delpech, V

    2014-01-16

    In 2009, Public Health England (PHE) introduced the routine application of a recent infection testing algorithm (RITA) to new HIV diagnoses, where a positive RITA result indicates likely acquisition of infection in the previous six months. Laboratories submit serum specimens to PHE for testing using the HIV 1/2gO AxSYM assay modified for the determination of HIV antibody avidity. Results are classified according to avidity index and data on CD₄ count, antiretroviral treatment and the presence of an AIDS-defining illness. Between 2009 and 2011, 38.4% (6,966/18,134) of new HIV diagnoses in England, Wales and Northern Ireland were tested. Demographic characteristics of those tested were similar to all persons with diagnosed HIV. Overall, recent infection was 14.7% (1,022/6,966) and higher among men who have sex with men (MSM) (22.3%, 720/3,223) compared with heterosexual men and women (7.8%, 247/3,164). Higher proportions were among persons aged 15-24 years compared with those ≥50 years (MSM 31.2% (139/445) vs 13.6% (42/308); heterosexual men and women 17.3% (43/249) vs 6.2% (31/501)). Among heterosexual men and women, black Africans were least likely to have recent infection compared with whites (4.8%, 90/1,892 vs 13.3%, 97/728; adjusted odds ratio: 0.6; 95% CI: 0.4-0.9). Our results indicate evidence of ongoing HIV transmission during the study period, particularly among MSM.

  6. Identification of drought in Dhalai river watershed using MCDM and ANN models

    Science.gov (United States)

    Aher, Sainath; Shinde, Sambhaji; Guha, Shantamoy; Majumder, Mrinmoy

    2017-03-01

    An innovative approach for drought identification is developed using Multi-Criteria Decision Making (MCDM) and Artificial Neural Network (ANN) models from surveyed drought parameter data around the Dhalai river watershed in Tripura hinterlands, India. Total eight drought parameters, i.e., precipitation, soil moisture, evapotranspiration, vegetation canopy, cropping pattern, temperature, cultivated land, and groundwater level were obtained from expert, literature and cultivator survey. Then, the Analytic Hierarchy Process (AHP) and Analytic Network Process (ANP) were used for weighting of parameters and Drought Index Identification (DII). Field data of weighted parameters in the meso scale Dhalai River watershed were collected and used to train the ANN model. The developed ANN model was used in the same watershed for identification of drought. Results indicate that the Limited-Memory Quasi-Newton algorithm was better than the commonly used training method. Results obtained from the ANN model shows the drought index developed from the study area ranges from 0.32 to 0.72. Overall analysis revealed that, with appropriate training, the ANN model can be used in the areas where the model is calibrated, or other areas where the range of input parameters is similar to the calibrated region for drought identification.

  7. Using ANN and EPR models to predict carbon monoxide concentrations in urban area of Tabriz

    Directory of Open Access Journals (Sweden)

    Mohammad Shakerkhatibi

    2015-09-01

    Full Text Available Background: Forecasting of air pollutants has become a popular topic of environmental research today. For this purpose, the artificial neural network (AAN technique is widely used as a reliable method for forecasting air pollutants in urban areas. On the other hand, the evolutionary polynomial regression (EPR model has recently been used as a forecasting tool in some environmental issues. In this research, we compared the ability of these models to forecast carbon monoxide (CO concentrations in the urban area of Tabriz city. Methods: The dataset of CO concentrations measured at the fixed stations operated by the East Azerbaijan Environmental Office along with meteorological data obtained from the East Azerbaijan Meteorological Bureau from March 2007 to March 2013, were used as input for the ANN and EPR models. Results: Based on the results, the performance of ANN is more reliable in comparison with EPR. Using the ANN model, the correlation coefficient values at all monitoring stations were calculated above 0.85. Conversely, the R2 values for these stations were obtained <0.41 using the EPR model. Conclusion: The EPR model could not overcome the nonlinearities of input data. However, the ANN model displayed more accurate results compared to the EPR. Hence, the ANN models are robust tools for predicting air pollutant concentrations.

  8. Simulation model of ANN based maximum power point tracking controller for solar PV system

    Energy Technology Data Exchange (ETDEWEB)

    Rai, Anil K.; Singh, Bhupal [Department of Electrical and Electronics Engineering, Ajay Kumar Garg Engineering College, Ghaziabad 201009 (India); Kaushika, N.D.; Agarwal, Niti [School of Research and Development, Bharati Vidyapeeth College of Engineering, A-4 Paschim Vihar, New Delhi 110063 (India)

    2011-02-15

    In this paper the simulation model of an artificial neural network (ANN) based maximum power point tracking controller has been developed. The controller consists of an ANN tracker and the optimal control unit. The ANN tracker estimates the voltages and currents corresponding to a maximum power delivered by solar PV (photovoltaic) array for variable cell temperature and solar radiation. The cell temperature is considered as a function of ambient air temperature, wind speed and solar radiation. The tracker is trained employing a set of 124 patterns using the back propagation algorithm. The mean square error of tracker output and target values is set to be of the order of 10{sup -5} and the successful convergent of learning process takes 1281 epochs. The accuracy of the ANN tracker has been validated by employing different test data sets. The control unit uses the estimates of the ANN tracker to adjust the duty cycle of the chopper to optimum value needed for maximum power transfer to the specified load. (author)

  9. RegnANN: Reverse Engineering Gene Networks using Artificial Neural Networks.

    Directory of Open Access Journals (Sweden)

    Marco Grimaldi

    Full Text Available RegnANN is a novel method for reverse engineering gene networks based on an ensemble of multilayer perceptrons. The algorithm builds a regressor for each gene in the network, estimating its neighborhood independently. The overall network is obtained by joining all the neighborhoods. RegnANN makes no assumptions about the nature of the relationships between the variables, potentially capturing high-order and non linear dependencies between expression patterns. The evaluation focuses on synthetic data mimicking plausible submodules of larger networks and on biological data consisting of submodules of Escherichia coli. We consider Barabasi and Erdös-Rényi topologies together with two methods for data generation. We verify the effect of factors such as network size and amount of data to the accuracy of the inference algorithm. The accuracy scores obtained with RegnANN is methodically compared with the performance of three reference algorithms: ARACNE, CLR and KELLER. Our evaluation indicates that RegnANN compares favorably with the inference methods tested. The robustness of RegnANN, its ability to discover second order correlations and the agreement between results obtained with this new methods on both synthetic and biological data are promising and they stimulate its application to a wider range of problems.

  10. Development and Application of ANN Model for Worker Assignment into Virtual Cells of Large Sized Configurations

    International Nuclear Information System (INIS)

    Murali, R. V.; Fathi, Khalid; Puri, A. B.

    2010-01-01

    This paper presents an extended version of study already undertaken on development of an artificial neural networks (ANNs) model for assigning workforce into virtual cells under virtual cellular manufacturing systems (VCMS) environments. Previously, the same authors have introduced this concept and applied it to virtual cells of two-cell configuration and the results demonstrated that ANNs could be a worth applying tool for carrying out workforce assignments. In this attempt, three-cell configurations problems are considered for worker assignment task. Virtual cells are formed under dual resource constraint (DRC) context in which the number of available workers is less than the total number of machines available. Since worker assignment tasks are quite non-linear and highly dynamic in nature under varying inputs and conditions and, in parallel, ANNs have the ability to model complex relationships between inputs and outputs and find similar patterns effectively, an attempt was earlier made to employ ANNs into the above task. In this paper, the multilayered perceptron with feed forward (MLP-FF) neural network model has been reused for worker assignment tasks of three-cell configurations under DRC context and its performance at different time periods has been analyzed. The previously proposed worker assignment model has been reconfigured and cell formation solutions available for three-cell configuration in the literature are used in combination to generate datasets for training ANNs framework. Finally, results of the study have been presented and discussed.

  11. Cooperação no APL de Santa Rita do Sapucaí.

    Directory of Open Access Journals (Sweden)

    Ana Rosa de Sousa

    2015-02-01

    Full Text Available Neste trabalho, apresentam-se os principais resultados de pesquisa na qual se investigaram os construtos explicativos das relações de cooperação entre as empresas integrantes do arranjo produtivo local (APL localizado na cidade de Santa Rita do Sapucaí, em Minas Gerais. Para tanto, recuperaram-se alguns aspectos da gênese, do desenvolvimento e da configuração do referido arranjo. Posteriormente, foi elaborada uma proposta teórico-metodológica que serviu de referência para a produção de explicações sobre relações entre os construtos cooperação, confiança, benefícios, entre outros. Para testar e validar a referida proposta, aplicaram-se duas técnicas de análise multivariada: análise fatorial e regressão polinomial. As análises dos resultados da pesquisa evidenciaram a existência de correlações que indicam percepção positiva dos gestores em relação à governança promovida no âmbito do arranjo produtivo e aos benefícios advindos da cooperação. Estes últimos são vistos pelos gestores como geradores de algumas vantagens individuais e coletivas para as empresas participantes da pesquisa. Finalmente, os resultados desta pesquisa contrariam algumas formulações da proposta teórico-metodológica utilizada para explicar as relações de confiança construídas entre as empresas que atuam numa mesma base territorial. Indicam ainda que esse APL exemplificaria bem a importância de dois elementos institucionais: a governança (no caso, Sindicato das Indústrias de Aparelhos Elétricos, Eletrônicos e Similares do Vale da Eletrônica – Sindvel – e poder público local e a interveniência de entidades educacionais que, além de assegurarem a qualificação da mão de obra, assumiram a tarefa de incubar empresas. Não parece inapropriado afirmar que o APL deve a sua criação e, mesmo, o seu desenvolvimento à atuação desses entes, conjuminada com a ação de pessoas visionárias, que ocuparam cargos diretivos

  12. A page is turned with the departure of Anne-Sylvie Catherin

    CERN Multimedia

    Staff Association

    2016-01-01

    The Staff Association wants to thank Anne Sylvie Catherin for her achievements during her career at CERN, and in particular during her mandate of head of the Human Resources Department. Anne-Sylvie Catherin arrived at CERN as a lawyer specialized in labor law of International Organizations, and she brought along her knowledge, as well as an unparalleled energy and professionalism. The Staff Association has particularly appreciated her collaborative approach during discussions in the concertation process. This attitude has clearly contributed to the implementation of significant change in the management of human resources, while preserving social peace. We expect that the person who will succeed Anne-Sylvie Catherin will have the same constructive attitude, in respect of the concertation process, as well as a continuity in the definition and implementation of HR processes. Finally, we hope that the new head of HR will be able to develop a long-term vision for the Organization and its staff, measuring to the vi...

  13. Artificial neural network (ANN) approach for modeling Zn(II) adsorption in batch process

    Energy Technology Data Exchange (ETDEWEB)

    Yildiz, Sayiter [Engineering Faculty, Cumhuriyet University, Sivas (Turkmenistan)

    2017-09-15

    Artificial neural networks (ANN) were applied to predict adsorption efficiency of peanut shells for the removal of Zn(II) ions from aqueous solutions. Effects of initial pH, Zn(II) concentrations, temperature, contact duration and adsorbent dosage were determined in batch experiments. The sorption capacities of the sorbents were predicted with the aid of equilibrium and kinetic models. The Zn(II) ions adsorption onto peanut shell was better defined by the pseudo-second-order kinetic model, for both initial pH, and temperature. The highest R{sup 2} value in isotherm studies was obtained from Freundlich isotherm for the inlet concentration and from Temkin isotherm for the sorbent amount. The high R{sup 2} values prove that modeling the adsorption process with ANN is a satisfactory approach. The experimental results and the predicted results by the model with the ANN were found to be highly compatible with each other.

  14. Modelling and automatic reactive power control of isolated wind-diesel hybrid power systems using ANN

    International Nuclear Information System (INIS)

    Bansal, R.C.

    2008-01-01

    This paper presents an artificial neural network (ANN) based approach to tune the parameters of the static var compensator (SVC) reactive power controller over a wide range of typical load model parameters. The gains of PI (proportional integral) based SVC are optimised for typical values of the load voltage characteristics (n q ) by conventional techniques. Using the generated data, the method of multi-layer feed forward ANN with error back propagation training is employed to tune the parameters of the SVC. An ANN tuned SVC controller has been applied to control the reactive power of a variable slip/speed isolated wind-diesel hybrid power system. It is observed that the maximum deviations of all parameters are more for larger values of n q . It has been shown that initially synchronous generator supplies the reactive power required by the induction generator and/or load, and the latter reactive power is purely supplied by the SVC

  15. Quick and reliable estimation of power distribution in a PHWR by ANN

    International Nuclear Information System (INIS)

    Dubey, B.P.; Jagannathan, V.; Kataria, S.K.

    1998-01-01

    Knowledge of the distribution of power in all the channels of a Pressurised Heavy Water Reactor (PHWR) as a result of a perturbation caused by one or more of the regulating devices is very important from the operation and maintenance point of view of the reactor. Theoretical design codes available for this purpose take several minutes to calculate the channel power distribution on modern PCs. Artificial Neural networks (ANNs) have been employed in predicting channel power distribution of Indian PHWRs for any given configuration of regulating devices of the reactor. ANNs produce the result much faster and with good accuracy. This paper describes the methodology of ANN, its reliability, the validation range, and scope for its possible on-line use in the actual reactor

  16. Mapping brain circuits of reward and motivation: in the footsteps of Ann Kelley.

    Science.gov (United States)

    Richard, Jocelyn M; Castro, Daniel C; Difeliceantonio, Alexandra G; Robinson, Mike J F; Berridge, Kent C

    2013-11-01

    Ann Kelley was a scientific pioneer in reward neuroscience. Her many notable discoveries included demonstrations of accumbens/striatal circuitry roles in eating behavior and in food reward, explorations of limbic interactions with hypothalamic regulatory circuits, and additional interactions of motivation circuits with learning functions. Ann Kelley's accomplishments inspired other researchers to follow in her footsteps, including our own laboratory group. Here we describe results from several lines of our research that sprang in part from earlier findings by Kelley and colleagues. We describe hedonic hotspots for generating intense pleasure 'liking', separate identities of 'wanting' versus 'liking' systems, a novel role for dorsal neostriatum in generating motivation to eat, a limbic keyboard mechanism in nucleus accumbens for generating intense desire versus intense dread, and dynamic limbic transformations of learned memories into motivation. We describe how origins for each of these themes can be traced to fundamental contributions by Ann Kelley. Copyright © 2013 Elsevier Ltd. All rights reserved.

  17. Modelling and automatic reactive power control of isolated wind-diesel hybrid power systems using ANN

    Energy Technology Data Exchange (ETDEWEB)

    Bansal, R.C. [Electrical and Electronics Engineering Division, School of Engineering and Physics, The University of the South Pacific, Suva (Fiji)

    2008-02-15

    This paper presents an artificial neural network (ANN) based approach to tune the parameters of the static var compensator (SVC) reactive power controller over a wide range of typical load model parameters. The gains of PI (proportional integral) based SVC are optimised for typical values of the load voltage characteristics (n{sub q}) by conventional techniques. Using the generated data, the method of multi-layer feed forward ANN with error back propagation training is employed to tune the parameters of the SVC. An ANN tuned SVC controller has been applied to control the reactive power of a variable slip/speed isolated wind-diesel hybrid power system. It is observed that the maximum deviations of all parameters are more for larger values of n{sub q}. It has been shown that initially synchronous generator supplies the reactive power required by the induction generator and/or load, and the latter reactive power is purely supplied by the SVC. (author)

  18. Artificial neural network (ANN) approach for modeling Zn(II) adsorption in batch process

    International Nuclear Information System (INIS)

    Yildiz, Sayiter

    2017-01-01

    Artificial neural networks (ANN) were applied to predict adsorption efficiency of peanut shells for the removal of Zn(II) ions from aqueous solutions. Effects of initial pH, Zn(II) concentrations, temperature, contact duration and adsorbent dosage were determined in batch experiments. The sorption capacities of the sorbents were predicted with the aid of equilibrium and kinetic models. The Zn(II) ions adsorption onto peanut shell was better defined by the pseudo-second-order kinetic model, for both initial pH, and temperature. The highest R"2 value in isotherm studies was obtained from Freundlich isotherm for the inlet concentration and from Temkin isotherm for the sorbent amount. The high R"2 values prove that modeling the adsorption process with ANN is a satisfactory approach. The experimental results and the predicted results by the model with the ANN were found to be highly compatible with each other.

  19. Sam Thompson, Stewart Parker, and the lineage of northern Irish dramaDOI:10.5007/2175-8026.2010n58p179

    Directory of Open Access Journals (Sweden)

    Marilynn Richtarik

    2010-01-01

    Full Text Available Northern Irish dramatist Stewart Parker (1941-1988 wrote plays typically valued for their wit, intellectual content, and formal experimentation. Nonetheless, he was profoundly influenced as a young man by a very different sort of playwright. Sam Thompson (1916-1965, who began his working life in the Belfast shipyards, squarely confronted Northern Irish sectarianism in his plays. His sense of the political potential of drama left an enduring mark on Parker, who organized and edited Thompson's manuscripts several years after his untimely death. Although their dramatic writings bear little resemblance to each other, the two writers should be regarded as united in a common Northern Irish dramatic tradition by virtue of their shared socialist outlook, belief in the importance of individual stands against conformity, and sense of theatre's social mission.

  20. Prediction of scour below submerged pipeline crossing a river using ANN.

    Science.gov (United States)

    Azamathulla, H M; Zakaria, Nor Azazi

    2011-01-01

    The process involved in the local scour below pipelines is so complex that it makes it difficult to establish a general empirical model to provide accurate estimation for scour. This paper describes the use of artificial neural networks (ANN) to estimate the pipeline scour depth. The data sets of laboratory measurements were collected from published works and used to train the network or evolve the program. The developed networks were validated by using the observations that were not involved in training. The performance of ANN was found to be more effective when compared with the results of regression equations in predicting the scour depth around pipelines.

  1. Effectiveness of ANN for seismic behaviour prediction considering geometric configuration effect in concrete gravity dams

    Directory of Open Access Journals (Sweden)

    Mohd. Saqib

    2016-09-01

    Full Text Available In this study, an Artificial Neural Networks (ANN model is built and verified for quick estimation of the structural parameter obtained for a concrete gravity dam section due to seismic excitation. The database of numerous inputs and outputs obtained through Abaqus which are further converted into dimensionless forms in the statistical software (MATLAB to build the ANN model. The developed model can be used for accurate estimation of this parameter. The results showed an excellent capability of the model to predict the outputs with high accuracy and reduced computational time.

  2. Aspekte van die outeursfunksie in Antjie Krog se Lady Anne (1989)

    OpenAIRE

    M. Crous

    2002-01-01

    Aspects of the author function in Antjie Krog’s Lady Anne (1989) The purpose of this essay is to investigate the Foucauldian notion of the so-called “author function” in Antjie Krog’s seventh volume of poetry, viz. Lady Anne (1989). It is an attempt to show how the notion of the death of the author (Barthes) links up with this theorisation of Foucault. Furthermore, it is also an attempt to indicate the characteristic features of the so-called “author function” in the late eighties in Afr...

  3. "I am the vampire for these times": Representations of Postmodernity in Anne Rice's The Vampire Chronicles

    OpenAIRE

    RINNE, ANTTI

    2013-01-01

    Anne Ricen The Vampire Chronicles -kirjasarjaa voidaan pitää vampyyrinarratiivien uutena aaltona 1970-luvulta lähtien. Ricen romaaneissa vampyyrit itse nousivat pääosaan kirjojen päähenkilöinä, ja romaanit tietyssä määrin irtautuivat vanhemman vampyyrikirjallisuuden kaavoista. Tutkimukseni aiheena ovat Anne Ricen romaanisarjan kolme ensimmäistä teosta, Interview with the Vampire (1976), The Vampire Lestat (1985) ja The Queen of the Damned (1988). Tutkielmani keskittyy siihen, kuinka kyseiset ...

  4. Crossing Canadian Cultural Borders: A study of the Aboriginal/White Stereotypical Relations in George Ryga's The Ecstasy of Rita Joe

    Directory of Open Access Journals (Sweden)

    Maram M. Samman

    2017-12-01

    Full Text Available This paper traces the intercultural journey of a young Aboriginal girl into the hegemonic white society. Rita Joe crossed the imaginary border that separates her reserve from the other Canadian society living in the urban developed city. Through this play, George Ryga aims at achieving liberation and social equality for the Aboriginals who are considered a colonized minority in their land. The research illustrates how Ryga represented his personal version of the colonial Aboriginal history to provide an empowering body narrative that supports their identity in the present and resists the erosion of their culture and tradition. The play makes very strong statements to preserve the family, history and local heritage against this forced assimilation. It tells the truth as its playwright saw it. The play is about the trail of Rita Joe after she moved from her reserve in pursuit of the illusion of the city where she thought she would find freedom and social equality. In fact the audience and the readers are all on trial. Ryga is pointing fingers at everyone who is responsible for the plights of the Aboriginals as it is clear in the play. He questions the Whites’ stereotypical stand against the Aboriginals. The play is a direct criticism of the political, social and cultural systems in Canada. The paper reveals Aboriginals' acts of opposition to racism, assimilation and colonization as represented in The Ecstasy of Rita Joe.

  5. Avaliação da acidose metabólica em pacientes graves: método de Stewart-Fencl-Figge versus a abordagem tradicional de henderson-hasselbalch Assessment of metabolic acidosis in critically ill patients: method of Stewart-Fencl-Figge versus the traditional henderson-hasselbalch approach

    Directory of Open Access Journals (Sweden)

    Manuela Borges Gavaza Barbosa

    2006-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Rever estratégias de avaliação da acidose metabólica dando ênfase ao método de Stewart-Fencl-Figge versus a abordagem tradicional de Henderson-Hasselbalch. CONTEÚDO: A acidose metabólica é um distúrbio comum em pacientes criticamente enfermos, sendo importante causa de depressão da função miocárdica e sensível indicador de má perfusão tissular. Tradicionalmente, é avaliada através do método de Henderson-Hasselbalch no qual a gasometria arterial fornece informações sobre a existência e o tipo de distúrbio ácido-básico. Porém, nem sempre, esse método é capaz de explicar os seus mecanismos causais e, por isso, muitos estudos têm sido feitos na tentativa de melhorar sua interpretação. O método de Stewart-Fencl-Figge, calculado através de fórmula matemática, em que além da gasometria arterial, são utilizados níveis séricos de vários eletrólitos, lactato e albumina, nos fornece informações mais fidedignas permitindo detectar anormalidades metabólicas mistas e estimar a magnitude de cada componente, principalmente na presença de múltiplas disfunções orgânicas. Nesses pacientes, a presença de ânions não mensurados no plasma é importante mecanismo de acidose metabólica e sua detecção precoce é fundamental para se evitar efeitos deletérios sobre o organismo. CONCLUSÕES: A abordagem tradicional de Henderson-Hasselbalch falha em analisar os mecanismos da acidose metabólica e possui muitas variáveis que interferem no seu resultado, principalmente no paciente criticamente enfermo. O método de Stewart-Fencl-Figge proporciona abordagem mais completa para avaliação da acidose metabólica, sugerindo seus mecanismos e orientando a terapêutica. Como alternativa, o anion gap corrigido pela albumina e lactato parece ser tão eficiente em identificar a presença de anions não mensurados quanto o método de Stewart.BACKGROUND AND OBJECTIVES: To review strategies of assessment

  6. Prediction of IRI in short and long terms for flexible pavements: ANN and GMDH methods

    NARCIS (Netherlands)

    Ziari, H.; Sobhani, J.; Ayoubinejad, J.; Hartmann, Timo

    2015-01-01

    Prediction of pavement condition is one of the most important issues in pavement management systems. In this paper, capabilities of artificial neural networks (ANNs) and group method of data handling (GMDH) methods in predicting flexible pavement conditions were analysed in three levels: in 1 year,

  7. Ann O'Mara, PhD, RN, MPH | Division of Cancer Prevention

    Science.gov (United States)

    Dr. Ann O'Mara is Head of Palliative Research in the NCI Division of Cancer Prevention. She manages a portfolio of symptom management and palliative and end-of-life care research projects. The majority of these projects focus on the more common morbidities associated with cancer and its treatment, e.g., pain, chemotherapy induced neuropathy, fatigue, sleep disturbances, and

  8. The Sally-Anne Test: An Interactional Analysis of a Dyadic Assessment

    Science.gov (United States)

    Korkiakangas, Terhi; Dindar, Katja; Laitila, Aarno; Kärnä, Eija

    2016-01-01

    Background: The Sally-Anne test has been extensively used to examine children's theory of mind understanding. Many task-related factors have been suggested to impact children's performance on this test. Yet little is known about the interactional aspects of such dyadic assessment situations that might contribute to the ways in which children…

  9. 75 FR 23745 - Jo-Ann Stores, Inc., Provisional Acceptance of a Settlement Agreement and Order

    Science.gov (United States)

    2010-05-04

    ... Acceptance of a Settlement Agreement and Order AGENCY: Consumer Product Safety Commission. ACTION: Notice... under the laws of the State of Ohio, with its principal offices located in Hudson, Ohio. At all times relevant hereto, Jo-Ann imported, offered for sale and sold various children's products. Staff Allegations...

  10. Practitioner Profile: An Interview with Anne Brennan Malec, Ph.D.

    Directory of Open Access Journals (Sweden)

    Anne Brennan Malec

    2015-12-01

    Full Text Available Dr. Anne Brennan Malec is the founder and managing partner of Symmetry Counseling, a counseling, coaching, and psychotherapy group practice located in downtown Chicago. She has been the driving force behind Symmetry Counseling’s success – what started in 2011 with six offices and five counselors now houses over 25 clinicians.

  11. [Reinhold Reith. Torsten Meyer (Hrsg.) Luxus und Konsum : eine historische Annäherung] / Raimo Pullat

    Index Scriptorium Estoniae

    Pullat, Raimo, 1935-

    2009-01-01

    Arvustus: Reith, Reinhold. Torsten Meyer (Hrsg.) Luxus und Konsum : eine historische Annäherung. Cottbuser Studien zur Geschichte von Technik, Arbeit und Umwelt. hrsg. von Günter Bayerl. Bd. 21. 2003. Collegium Johann Beckmann'i kolmanda teaduskonverentsi ettekannete kogumikust

  12. 76 FR 80392 - Notice of Inventory Completion: University of Michigan Museum of Anthropology, Ann Arbor, MI

    Science.gov (United States)

    2011-12-23

    ...: University of Michigan Museum of Anthropology, Ann Arbor, MI AGENCY: National Park Service, Interior. ACTION... Michigan officials and its Museum of Anthropology professional staff in consultation with representatives... accessioned into the Museum of Anthropology. Between 2007 and 2009 the remains were inventoried at the...

  13. 76 FR 73670 - Notice of Inventory Completion: University of Michigan Museum of Anthropology, Ann Arbor, MI

    Science.gov (United States)

    2011-11-29

    ...: University of Michigan Museum of Anthropology, Ann Arbor, MI AGENCY: National Park Service, Interior. ACTION... Museum of Anthropology NAGPRA collections staff in consultation with representatives of the Bay Mills... Anthropology purchased the human remains from Reverend L. P. Rowland in November of 1924 as part of a larger...

  14. Anne Applebaum: Kas NATO lõpp on lähedal? / Indrek Veiserik

    Index Scriptorium Estoniae

    Veiserik, Indrek

    2009-01-01

    USA ajakirjaniku Anne Applebaumi kriitikast NATO kui organisatsiooni toimimise ja Afganistani missiooni suhtes. Kesknädala arvates võiks president Toomas Hendrik Ilves, kes on annetanud A. Applebaumile Maarjamaa Risti III klassi teenetemärgi, kuulata tema välispoliitilisi seisukohti. Viidatakse ka Kanada kindrali Rick Hillieri kriitikale NATO kohta

  15. Beginning and ending of Anne Hebert's 'Burden of Dreams' : Polysemy of a journey of identity

    NARCIS (Netherlands)

    Lintvelt, Jaap

    2007-01-01

    The protagonist of Anne Hebert's Burden of Dreams (1992) goes on a journey from Quebec to Paris that contributes to the evolution of his personal and cultural identity The novel's title already tells us that "dreams" will play. a key role both on a thematic level and in shaping the reading protocol.

  16. A call for water-efficient technologies (an interview with dr. Anne Elings)

    NARCIS (Netherlands)

    Elings, A.

    2012-01-01

    During the recent International Flower Trade Expo in Nairobi, Wageningen UR Greenhouse Horticulture project leader and greenhouse horticulture specialist Anne Elings pointed out that Kenya is not a water scarce country but management of the same is wanting. HortiNews had a chat with him.

  17. A Fault Diagnosis Model Based on LCD-SVD-ANN-MIV and VPMCD for Rotating Machinery

    Directory of Open Access Journals (Sweden)

    Songrong Luo

    2016-01-01

    Full Text Available The fault diagnosis process is essentially a class discrimination problem. However, traditional class discrimination methods such as SVM and ANN fail to capitalize the interactions among the feature variables. Variable predictive model-based class discrimination (VPMCD can adequately use the interactions. But the feature extraction and selection will greatly affect the accuracy and stability of VPMCD classifier. Aiming at the nonstationary characteristics of vibration signal from rotating machinery with local fault, singular value decomposition (SVD technique based local characteristic-scale decomposition (LCD was developed to extract the feature variables. Subsequently, combining artificial neural net (ANN and mean impact value (MIV, ANN-MIV as a kind of feature selection approach was proposed to select more suitable feature variables as input vector of VPMCD classifier. In the end of this paper, a novel fault diagnosis model based on LCD-SVD-ANN-MIV and VPMCD is proposed and proved by an experimental application for roller bearing fault diagnosis. The results show that the proposed method is effective and noise tolerant. And the comparative results demonstrate that the proposed method is superior to the other methods in diagnosis speed, diagnosis success rate, and diagnosis stability.

  18. Application of ANN-SCE model on the evaluation of automatic generation control performance

    Energy Technology Data Exchange (ETDEWEB)

    Chang-Chien, L.R.; Lo, C.S.; Lee, K.S. [National Cheng Kung Univ., Tainan, Taiwan (China)

    2005-07-01

    An accurate evaluation of load frequency control (LFC) performance is needed to balance minute-to-minute electricity generation and demand. In this study, an artificial neural network-based system control error (ANN-SCE) model was used to assess the performance of automatic generation controls (AGC). The model was used to identify system dynamics for control references in supplementing AGC logic. The artificial neural network control error model was used to track a single area's LFC dynamics in Taiwan. The model was used to gauge the impacts of regulation control. Results of the training, evaluating, and projecting processes showed that the ANN-SCE model could be algebraically decomposed into components corresponding to different impact factors. The SCE information obtained from testing of various AGC gains provided data for the creation of a new control approach. The ANN-SCE model was used in conjunction with load forecasting and scheduled generation data to create an ANN-SCE identifier. The model successfully simulated SCE dynamics. 13 refs., 10 figs.

  19. Mart ja Mari-Ann Susi taotlevad omanikena Concordia pankrotti / Andri Maimets

    Index Scriptorium Estoniae

    Maimets, Andri

    2003-01-01

    Concordia Ülikooli rektori kohast loobunud Mart Susi ning prorektori ametikohalt lahkunud Mari-Ann Susi taotlevad neile kuuluvat ülikooli pidanud miljonivõlgades firma pankrotti. Hiljuti loodi õppejõududest, tudengitest js töötajatest mittetulundusühing Concordia Akadeemiline Ühisus (CAU), selle nõukogu esimees on Hagi Šein

  20. Joseph Campbell, Jung, Anne Tyler, and "The Cards": The Spiritual Journey in "Searching for Caleb."

    Science.gov (United States)

    Thomson, Karen M.

    Joseph Campbell, Carl Jung, and Anne Tyler have all dealt with spiritual journeys and card reading in their writings. In his book "Tarot Revelations," Joseph Campbell discusses his first association with tarot cards, dating from 1943, when he was introduced to the symoblism of playing cards by his friend and mentor, Heinrich Zimmer. Carl…

  1. Wind speed forecasting in three different regions of Mexico, using a hybrid ARIMA-ANN model

    Energy Technology Data Exchange (ETDEWEB)

    Cadenas, Erasmo [Facultad de Ingenieria Mecanica, Universidad Michoacana de San Nicolas de Hidalgo, Santiago Tapia No. 403, Centro (Mexico); Rivera, Wilfrido [Centro de Ivestigacion en Energia, Universidad Nacional Autonoma de Mexico, Apartado Postal 34, Temixco 62580, Morelos (Mexico)

    2010-12-15

    In this paper the wind speed forecasting in the Isla de Cedros in Baja California, in the Cerro de la Virgen in Zacatecas and in Holbox in Quintana Roo is presented. The time series utilized are average hourly wind speed data obtained directly from the measurements realized in the different sites during about one month. In order to do wind speed forecasting Hybrid models consisting of Autoregressive Integrated Moving Average (ARIMA) models and Artificial Neural Network (ANN) models were developed. The ARIMA models were first used to do the wind speed forecasting of the time series and then with the obtained errors ANN were built taking into account the nonlinear tendencies that the ARIMA technique could not identify, reducing with this the final errors. Once the Hybrid models were developed 48 data out of sample for each one of the sites were used to do the wind speed forecasting and the results were compared with the ARIMA and the ANN models working separately. Statistical error measures such as the mean error (ME), the mean square error (MSE) and the mean absolute error (MAE) were calculated to compare the three methods. The results showed that the Hybrid models predict the wind velocities with a higher accuracy than the ARIMA and ANN models in the three examined sites. (author)

  2. Assessment of spatial distribution of soil heavy metals using ANN-GA, MSLR and satellite imagery.

    Science.gov (United States)

    Naderi, Arman; Delavar, Mohammad Amir; Kaboudin, Babak; Askari, Mohammad Sadegh

    2017-05-01

    This study aims to assess and compare heavy metal distribution models developed using stepwise multiple linear regression (MSLR) and neural network-genetic algorithm model (ANN-GA) based on satellite imagery. The source identification of heavy metals was also explored using local Moran index. Soil samples (n = 300) were collected based on a grid and pH, organic matter, clay, iron oxide contents cadmium (Cd), lead (Pb) and zinc (Zn) concentrations were determined for each sample. Visible/near-infrared reflectance (VNIR) within the electromagnetic ranges of satellite imagery was applied to estimate heavy metal concentrations in the soil using MSLR and ANN-GA models. The models were evaluated and ANN-GA model demonstrated higher accuracy, and the autocorrelation results showed higher significant clusters of heavy metals around the industrial zone. The higher concentration of Cd, Pb and Zn was noted under industrial lands and irrigation farming in comparison to barren and dryland farming. Accumulation of industrial wastes in roads and streams was identified as main sources of pollution, and the concentration of soil heavy metals was reduced by increasing the distance from these sources. In comparison to MLSR, ANN-GA provided a more accurate indirect assessment of heavy metal concentrations in highly polluted soils. The clustering analysis provided reliable information about the spatial distribution of soil heavy metals and their sources.

  3. Process Control Strategies for Dual-Phase Steel Manufacturing Using ANN and ANFIS

    Science.gov (United States)

    Vafaeenezhad, H.; Ghanei, S.; Seyedein, S. H.; Beygi, H.; Mazinani, M.

    2014-11-01

    In this research, a comprehensive soft computational approach is presented for the analysis of the influencing parameters on manufacturing of dual-phase steels. A set of experimental data have been gathered to obtain the initial database used for the training and testing of both artificial neural networks (ANN) and adaptive neuro-fuzzy inference system (ANFIS). The parameters used in the strategy were intercritical annealing temperature, carbon content, and holding time which gives off martensite percentage as an output. A fraction of the data set was chosen to train both ANN and ANFIS, and the rest was put into practice to authenticate the act of the trained networks while seeing unseen data. To compare the obtained results, coefficient of determination and root mean squared error indexes were chosen. Using artificial intelligence methods, it is not necessary to consider and establish a preliminary mathematical model and formulate its affecting parameters on its definition. In conclusion, the martensite percentages corresponding to the manufacturing parameters can be determined prior to a production using these controlling algorithms. Although the results acquired from both ANN and ANFIS are very encouraging, the proposed ANFIS has enhanced performance over the ANN and takes better effect on cost-reduction profit.

  4. Uudised : Indi-sahinad. Anne Erm ja Eero Raun on heliloojad. Imelaste lemmik on heavy metal

    Index Scriptorium Estoniae

    2007-01-01

    Ameerika laulja Kimya Dawson 7. juulil Kilingi-Nõmmel minifestivalil "Schilling". Pianist Martti Raide esitab festivali Eesti muusika päevad 2007 suurkontserdil 16. aprillil Eero Rauna klaveripala "Tritonata", üllatusheliloojaks on ka "Jazzkaare" produtsent Anne Erm. Inglismaal Noorte Talentide Rahvuslikus Akadeemias tehtud uuringust

  5. 78 FR 65382 - Notice of Inventory Completion: University of Michigan, Ann Arbor, MI

    Science.gov (United States)

    2013-10-31

    ....S.C. 3003, of the completion of an inventory of human remains under the control of the University of....R50000] Notice of Inventory Completion: University of Michigan, Ann Arbor, MI AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The University of Michigan has completed an inventory of human...

  6. 78 FR 65369 - Notice of Inventory Completion: University of Michigan, Ann Arbor, MI

    Science.gov (United States)

    2013-10-31

    ....S.C. 3003, of the completion of an inventory of human remains under the control of the University of....R50000] Notice of Inventory Completion: University of Michigan, Ann Arbor, MI AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The University of Michigan has completed an inventory of human...

  7. 78 FR 65366 - Notice of Inventory Completion: University of Michigan, Ann Arbor, MI

    Science.gov (United States)

    2013-10-31

    ....S.C. 3003, of the completion of an inventory of human remains under the control of the University of....R50000] Notice of Inventory Completion: University of Michigan, Ann Arbor, MI AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The University of Michigan has completed an inventory of human...

  8. "Boob teab" / Kalju Komissarov ja Rait Avestik ; kommenteerinud ja toimetanud Anneli Saro

    Index Scriptorium Estoniae

    Komissarov, Kalju, 1946-2017

    2010-01-01

    Teatriseminar sarjast "Eesti algupärandid Eesti teatris" toimus Tartu Kirjanduse Maja krüptis 28. märtsil 2005, seminari juhtis Anneli Saro. Urmas Lennuki näidendi kolmest lavastusest: Tallinna Linnateatris (esietendus 28. veebruaril 2004, lavastas Jaanus Rohumaa), Rakvere Teatris (esietendus 10. septembril 2004, lavastas Kalju Komissarov) ja Vikerraadios (esietendus 4. septembril 2004, lavastas Tamur Tohver)

  9. A comparative study of ANN and neuro-fuzzy for the prediction of ...

    Indian Academy of Sciences (India)

    Istanbul Technical University, Faculty of Civil Engineering, Hydraulics and Water. Resources Division, Maslak 34469, Istanbul, Turkey. Singh et al (2005) examined the potential of the ANN and neuro-fuzzy systems application for the prediction of dynamic constant of rockmass. However, the model proposed by them has ...

  10. Artificial neural network (ANN)-based prediction of depth filter loading capacity for filter sizing.

    Science.gov (United States)

    Agarwal, Harshit; Rathore, Anurag S; Hadpe, Sandeep Ramesh; Alva, Solomon J

    2016-11-01

    This article presents an application of artificial neural network (ANN) modelling towards prediction of depth filter loading capacity for clarification of a monoclonal antibody (mAb) product during commercial manufacturing. The effect of operating parameters on filter loading capacity was evaluated based on the analysis of change in the differential pressure (DP) as a function of time. The proposed ANN model uses inlet stream properties (feed turbidity, feed cell count, feed cell viability), flux, and time to predict the corresponding DP. The ANN contained a single output layer with ten neurons in hidden layer and employed a sigmoidal activation function. This network was trained with 174 training points, 37 validation points, and 37 test points. Further, a pressure cut-off of 1.1 bar was used for sizing the filter area required under each operating condition. The modelling results showed that there was excellent agreement between the predicted and experimental data with a regression coefficient (R 2 ) of 0.98. The developed ANN model was used for performing variable depth filter sizing for different clarification lots. Monte-Carlo simulation was performed to estimate the cost savings by using different filter areas for different clarification lots rather than using the same filter area. A 10% saving in cost of goods was obtained for this operation. © 2016 American Institute of Chemical Engineers Biotechnol. Prog., 32:1436-1443, 2016. © 2016 American Institute of Chemical Engineers.

  11. Friendly Letters on the Correspondence of Helen Keller, Anne Sullivan, and Alexander Graham Bell.

    Science.gov (United States)

    Blatt, Burton

    1985-01-01

    Excerpts from the letters between Alexander Graham Bell and Anne Sullivan and Helen Keller are given to illustrate the educational and personal growth of Helen Keller as well as the educational philosophy of Bell regarding the education of the deaf blind. (DB)

  12. The Nation behind the Diary: Anne Frank and the Holocaust of the Dutch Jews

    Science.gov (United States)

    Foray, Jennifer L.

    2011-01-01

    Since its first appearance in 1947, "The Diary of Anne Frank" has been translated into sixty-five different languages, including Welsh, Esperanto, and Faroese. Millions and perhaps even billions of readers, scattered throughout the globe and now spanning multiple generations, are familiar with the life and work of this young Jewish…

  13. Symbolism--The Main Artistic Style of Katherine Anne Porter's Short Stories

    Science.gov (United States)

    Wang, Ru

    2010-01-01

    The paper takes Katherine Anne Porter's two short stories: "Flowering Judas", "The Grave" as objects of study. It will try to analyze Porter's writing style through her imaginary conception, vivid psychological description and multiple symbolisms so that we can understand her studies and her attitudes to female psychological…

  14. Eye of the storm: analysis of shelter treatment records of evacuees to Acadiana from Hurricanes Katrina and Rita.

    Science.gov (United States)

    Caillouet, L Philip; Paul, P Joseph; Sabatier, Steven M; Caillouet, Kevin A

    2012-01-01

    The objective of this study is to gain insight into the medical needs of disaster evacuees, through a review of experiential data collected in evacuation shelters in the days and weeks following Hurricanes Katrina and Rita in 2005, to better prepare for similar events in the future. Armed with the information and insights provided herein, it is hoped that meaningful precautions and decisive actions can be taken by individuals, families, institutions, communities, and officials should the Louisiana Gulf Coast-or any other area with well-known vulnerabilities-be faced with a future emergency. Demographic and clinical data that were recorded on paper documents during triage and treatment in evacuation shelters were later transcribed into a computerized database management system, with cooperation of the Department of Health Information Management at The University of Louisiana at Lafayette. Analysis of those contemporaneously collected data was undertaken later by the Louisiana Center for Health Informatics. Evacuation shelters, Parish Health Units, and other locations including churches and community centers were the venue for ad hoc clinics in the Acadiana region of Louisiana. The evacuee-patients-3,329 of them-whose information is reflected in the subject dataset were among two geographically distinct but similarly distressed groups: 1) evacuees from Hurricane Katrina that devastated New Orleans and other locales near Louisiana and neighboring states in late August 2005 and 2) evacuees from Hurricane Rita that devastated Southwest Louisiana and neighboring areas of Texas in September 2005. Patient data were collected by physicians, nurses, and other volunteers associated with the Operation Minnesota Lifeline (OML) deployment during the weeks following the events. Volunteer clinicians from OML provided triage and treatment services and documented those services as paper medical records. As the focus of the OML "mission of mercy" was entirely on direct individually

  15. The provenance and Sm/Nd Model ages of siliciclastic supracrustal rocks of the Faina and Santa Rita Greenstone belts, Goias, Brazil

    International Nuclear Information System (INIS)

    Resende, Marcelo Goncalves; Jost, Hardy; Lima, Bruno Eustaquio Moreira; Teixeira, Alexandre de Amorim

    1999-01-01

    The Faina and Santa Rita greenstone belts are two N 60 deg C W trending synclinoria separated by a N 30 deg C E strike-slip fault and rest allochtonous on the adjacent Uva and Caicara granite-gneiss complexes. The belts are made up of lower metakomatiites, followed by metabasalts and thick metasedimentary sequences deposited under contrasting paleogeographic settings. In Faina, the sequence consists of two complete shelf cycles, the first resting on basalts by an erosional unconformity. In Santa Rita, the basalts give gradually place to carbonaceous metashales, unconformably overlain by metarhythmites. Provenance based on trace element geochemistry, mineral chemistry of chloride and muscovite, source-are modeling and REE elements indicate that protoliths of the first shelf cycle of Faina and the carbonaceous metashales of Santa Rita formed under the influence of a source area dominated by mafic ultramafic rocks, whilst during the sedimentation of the second shelf cycle and the metarhythmites of Santa Rita the source-area was dominated by TTG granitoids. Sm-Nd model ages of the lower sedimentary packages vary between 3.0 and 2.8 Ga and the upper between 2.7 and 2.6 Ga. These intervals coincide, respectively, with the estimated age of the underlying, and with the Sm-Nd, Rb-Sr e U-Pb ages of the main granitoids and gneisses of the adjacent complexes. The same data indicate that, during the sedimentation of the first shelf cycle of Faina and the carbonaceous metashales of Santa Rita, both basins had independent source-areas, but shared the same source during the upper sections. Weathering nature and intensity of the source-area calculated by means of geochemical a data suggest that the dramatic change of provenance from the lower to the upper sections is due to the shift from tectonically stable to unstable regimes, interpreted as resulting from the emergence of the island arc whose roots are represented by the adjacent granite-gneiss complexes. (author)

  16. Hurricanes Katrina and Rita and the Department of Veterans Affairs: a conceptual model for understanding the evacuation of nursing homes.

    Science.gov (United States)

    Dobalian, Aram; Claver, Maria; Fickel, Jacqueline J

    2010-01-01

    Hurricanes Katrina and Rita exposed significant flaws in US preparedness for catastrophic events and the nation's capacity to respond to them. These flaws were especially evident in the affected disaster areas' nursing homes, which house a particularly vulnerable population of frail older adults. Although evacuation of a healthcare facility is a key preparedness activity, there is limited research on factors that lead to effective evacuation. Our review of the literature on evacuation is focused on developing a conceptual framework to study future evacuations rather than as a comprehensive assessment of prior work. This paper summarizes what is known thus far about disaster response activities of nursing homes following natural and human-caused disasters, describes a conceptual model to guide future inquiry regarding this topic, and suggests future areas of research to further understand the decision-making process of nursing home facilitators regarding evacuating nursing home residents. To demonstrate the utility of the conceptual model and to provide guidance about effective practices and procedures, this paper focuses on the responses of Veterans Health Administration (VHA) nursing homes to the 2 hurricanes. Quarantelli's conceptual framework, as modified by Perry and Mushkatel, is useful in guiding the development of central hypotheses related to the decision-making that occurred in VA nursing homes and other healthcare facilities following Hurricanes Katrina and Rita. However, we define evacuation somewhat differently to account for the fact that evacuation may, in some instances, be permanent. Thus, we propose modifying this framework to improve its applicability beyond preventive evacuation. We need to better understand how disaster plans can be adapted to meet the needs of frail elders and other residents in nursing homes. Moreover, we must address identified gaps in the scientific literature with respect to health outcomes by tracking outcomes over time

  17. The Santa Rita Shear Zone: Major Mesozoic deformation along the western flank of the White-Inyo Range, CA

    Energy Technology Data Exchange (ETDEWEB)

    Brudos, T.C.; Paterson, S.R. (Univ. of Southern California, Los Angeles, CA (United States). Dept. of Geological Sciences)

    1993-04-01

    The Santa Rita Shear Zone (SRSZ), briefly described by Ross (1967), deforms the western part of the 164 Ma Santa Rita Flat pluton (SRFP), located SSE of Big Pine, CA. The SRSZ comprises a subvertical zone of solid-state deformation (strike N15E) over an area at least 13 km long by 2--3 km wide. Exposure of the shear zone is limited to the north and west by overlying Quaternary volcanics and basin fill within the Late Cenozoic Owens Valley graben. The SRSZ is larger than its present outcrop extent: strain magnitudes are highest within the westernmost exposures. The SRSZ along this western margin is a continuous zone of deformation comprising a mm-scale solid-state foliation containing igneous feldspars flattened into ovals with > 10:1 aspect ratios. The authors have identified three dike phases within the SRFP: (1) minor NE-striking Phase 1 dikes, comprising cm-scale aplites; (2) widespread m-scale Phase 2 dikes, which strike N10E; and (3) m-scale NW-striking Phase 3 mafic dikes. The Phase 1 and Phase 3 dikes are pre- and post-tectonic respectively; observations described below indicate the Phase 2 dikes are syn- to post-deformation. Deformation becomes localized along the Phase 2 dikes -- which are parallel to the orientation of the main body of the shear zone. Solid-state fabrics imposed on the Phase 2 dikes formed at higher temperatures than those within the SRFP, and in the east the SRFP is deformed only within a few cm of the dikes. They surmise syntectonic emplacement of the dikes into dislocational surfaces within the SRSZ, followed by solid-state deformation of the cooling dikes. Several workers have suggested the dikes within the SRFP are part of the 148 Ma independence dike swarm (referring to the Phase 2 or 3 dikes). If correct, this correlation indicates a Jurassic age for the SRSZ. Radiometric analyses of the dikes are in progress.

  18. Perbandingan Metode ANN-PSO Dan ANN-GA Dalam Pemodelan Komposisi Pakan Kambing Peranakan Etawa (PE Untuk Optimasi Kandungan Gizi

    Directory of Open Access Journals (Sweden)

    Canny Amerilyse Caesar

    2016-09-01

    Abstract Milk is one of the animal protein sources which it contains all of the substances needed by human body. The main milk producer cattle in Indonesia is dairy cow, however its milk production has not fulfilled the society needs. The alternative is the goat, the Etawa crossbreed (PE. The high quality of milk nutrients content is greatly influenced by some factors one of them, is the food factor. The PE goat livestock division of the UPT Cattle Breeding and the Cattle Food Greenery in Singosari-Malang still faces the problem, it is the low ability in giving the food composition for PE goat. This flaw affects the quality of the produced milk. It needs the artificial science of the milk nutrients contain in order to determine the food composition to produce premium milk with the optimum nutrients contain. The writer uses the method of the Artificial Neural Network (ANN and the Particle Swarm Optimization (PSO to make the modeling of goat food in optimizing the content of goat milk nutrients. In the analysis of the examination that is done with the case of 36 kg goat weight, also the food type used is the 70 % Odot grass and 30% Raja grass can increase the nutrients contain of the protein milk for 0.707% and decrease the fat nutrients contain for 0.879%. If uses the method of Artificial Neural Network (ANN and Genethic Algorithm (GA can increase the nutriens contain of the protein for 0.0852% and decrease the fat nutients contain for 2.3254%.   Key Words : Goat Milk, Optimization, Artificial Neural Network (ANN, Particle Swarm Optimization (PSO, Genetic Algorithm (GA, the food nutrients contain.

  19. Comparison of the accuracy of SST estimates by artificial neural networks (ANN) and other quantitative methods using radiolarian data from the Antarctic and Pacific Oceans

    Digital Repository Service at National Institute of Oceanography (India)

    Gupta, S.M.; Malmgren, B.A.

    ) regression, the maximum likelihood (ML) method, and artificial neural networks (ANNs), based on radiolarian faunal abundance data from surface sediments from the Antarctic and Pacific Oceans. Recent studies have suggested that ANNs may represent one...

  20. Anmeldelse: Anne Gjelsvik & Rikke Schubart : Women of ice and fire: Gender, Game of Thrones, and multiple media engagements, New York/London: Bloomsbury, 2016

    DEFF Research Database (Denmark)

    Konzack, Lars

    2017-01-01

    Anmeldelse af bogen Women of Ice and F ire: Gender, Game of Thrones redigeret af Anne Gjelsvik & Rikke Schubart.......Anmeldelse af bogen Women of Ice and F ire: Gender, Game of Thrones redigeret af Anne Gjelsvik & Rikke Schubart....

  1. The Muralla Pircada: an ancient Andean debris flow retention dam, Santa Rita B archaeological site, Chao Valley, Northern Peru

    Science.gov (United States)

    Brooks, William E.; Willett, Jason C.; Kent, Jonathan D.; Vasquez, Victor; Rosales, Teresa

    2005-01-01

    Debris flows caused by El Niño events, earthquakes, and glacial releases have affected northern Perú for centuries. The Muralla Pircada, a northeast-trending, 2.5 km long stone wall east of the Santa Rita B archaeological site (Moche-Chimú) in the Chao Valley, is field evidence that ancient Andeans recognized and, more importantly, attempted to mitigate the effects of debris flows. The Muralla is upstream from the site and is perpendicular to local drainages. It is 1–2 m high, up to 5 m wide, and is comprised of intentionally-placed, well-sorted, well-rounded, 20–30 cm cobbles and boulders from nearby streams. Long axes of the stones are gently inclined and parallel local drainage. Case-and-fill construction was used with smaller cobbles and pebbles used as fill. Pre-Muralla debris flows are indicated by meter-sized, angular boulders that were incorporated in-place into construction of the dam and are now exposed in breeches in the dam. Post-Muralla debris flows in the Chao Valley are indicated by meter-sized, angular boulders that now abut the retention dam.

  2. USGS environmental characterization of flood sediments left in the New Orleans area after Hurricanes Katrina and Rita, 2005--Progress Report

    Science.gov (United States)

    Plumlee, Geoffrey S.; Meeker, Gregory P.; Lovelace, John K.; Rosenbauer, Robert J.; Lamothe, Paul J.; Furlong, Edward T.; Demas, Charles R.

    2006-01-01

    Introduction: The flooding in the greater New Orleans area that resulted from Hurricanes Katrina and Rita in September, 2005, left behind accumulations of sediments up to many centimeters thick on streets, lawns, parking lots, and other flat surfaces. These flood sediment deposits have been the focus of extensive study by the US Environmental Protection Agency (EPA) and Louisiana Department of Environmental Quality (LDEQ) due to concerns that the sediments may contain elevated levels of heavy metals, organic contaminants, and microbes. The U.S. Geological Survey (USGS) is characterizing a limited number of flood sediment samples that were collected on September 15-16 and October 6-7, 2005, from the greater New Orleans area by personnel from the USGS Louisiana Water Science Center in Baton Rouge. Small samples (< 3 pints each) of wet to dry flood sediment were collected from 11 localities around downtown New Orleans on September 15, 2005, and two large samples (40 pints each) of wet flood sediment were collected from the Chalmette area on September 16. Twelve additional samples (8-10 pints each) were collected from New Orleans, Slidell, Rigolets, and Violet on October 6 and 7. The USGS characterization studies of these flood sediments are designed to produce data and interpretations regarding how the sediments and any contained contaminants may respond to environmental processes. This information will be of use to cleanup managers and DoI/USGS scientists assessing environmental impacts of the hurricanes and subsequent cleanup activities.

  3. A CONSTRUÇÃO DO LUGAR DE VIVER: PROJETO DE ASSENTAMENTO SANTA RITA EM JATAÍ – GO

    Directory of Open Access Journals (Sweden)

    Roberta Costa ROCHA

    2015-07-01

    Full Text Available A pesquisa da qual resulta este artigo tem como objeto o assentamento rural, enquanto modo de resistência camponesa para a sua permanência no campo, e a construção do lugar de viver nesse assentamento. Os atores da pesquisa são as famílias do Projeto de Assentamento Santa Rita, localizado no município de Jataí-GO, que, em um novo meio, constroem o seu lugar, dando-lhe significação e ressignificação enquanto lugar camponês. O estudo do lugar abre perspectivas para se pensar o viver e os processos de apropriação do espaço. Metodologicamente, os dados primários foram levantados através de entrevistas semiestruturadas e de aplicação de questionários e os dados secundários foram obtidos através de pesquisas bibliográficas, no intuito de aprofundar a discussão proposta.

  4. Observations of the structure and evolution of surface and flight-level wind asymmetries in Hurricane Rita (2005)

    Science.gov (United States)

    Rogers, Robert; Uhlhorn, Eric

    2008-11-01

    Knowledge of the magnitude and distribution of surface winds, including the structure of azimuthal asymmetries in the wind field, are important factors for tropical cyclone forecasting. With its ability to remotely measure surface wind speeds, the stepped frequency microwave radiometer (SFMR) has assumed a prominent role for the operational tropical cyclone forecasting community. An example of this instrument's utility is presented here, where concurrent measurements of aircraft flight-level and SFMR surface winds are used to document the wind field evolution over three days in Hurricane Rita (2005). The amplitude and azimuthal location (phase) of the wavenumber-1 asymmetry in the storm-relative winds varied at both levels over time. The peak was found to the right of storm track at both levels on the first day. By the third day, the peak in flight-level storm-relative winds remained to the right of storm track, but it shifted to left of storm track at the surface, resulting in a 60-degree shift between the surface and flight-level and azimuthal variations in the ratio of surface to flight-level winds. The asymmetric differences between the surface and flight-level maximum wind radii also varied, indicating a vortex whose tilt was increasing.

  5. A Cáritas brasileira e a Economia Popular Solidária: O Agente de Cáritas e a Caridade Libertadora (Brazilian Caritas and the Popular Solidarity Economy: The Agent of Caritas and the Charity Liberating) - DOI: 10.5752/P.2175-5841.2013v11n32p1506

    OpenAIRE

    Joannes Paulus Silva Forte; Alicia Ferreira Gonçalves

    2013-01-01

    O presente artigo analisa as ligações entre a Cáritas Brasileira e a Economia Popular Solidária a partir do trabalho do Agente de Cáritas. A problemática central do artigo remete às representações sociais que esses Agentes constroem em seus relatos sobre os princípios da Teologia da Libertação que norteiam os projetos em economia solidária da referida instituição religiosa. A metodologia de base qualitativa e etnográfica consistiu na realização da revisão bibliográfica, consulta a materiais i...

  6. FPGA implementation of adaptive ANN controller for speed regulation of permanent magnet stepper motor drives

    Energy Technology Data Exchange (ETDEWEB)

    Hasanien, Hany M., E-mail: Hanyhasanien@ieee.or [Dept. of Elec. Power and Machines, Faculty of Eng., Ain Shams Univ., Cairo (Egypt)

    2011-02-15

    This paper presents a novel adaptive artificial neural network (ANN) controller, which applies on permanent magnet stepper motor (PMSM) for regulating its speed. The dynamic response of the PMSM with the proposed controller is studied during the starting process under the full load torque and under load disturbance. The effectiveness of the proposed adaptive ANN controller is then compared with that of the conventional PI controller. The proposed methodology solves the problem of nonlinearities and load changes of PMSM drives. The proposed controller ensures fast and accurate dynamic response with an excellent steady state performance. Matlab/Simulink tool is used for this dynamic simulation study. The main contribution of this work is the implementation of the proposed controller on field programmable gate array (FPGA) hardware to drive the stepper motor. The driver is built on FPGA Spartan-3E Starter from Xilinx. Experimental results are presented to demonstrate the validity and effectiveness of the proposed control scheme.

  7. La presa di parola di Anne Hutchinson. Insubordinazione e conflitto nella giovane America puritana

    Directory of Open Access Journals (Sweden)

    Itala Vivan

    2016-04-01

    Full Text Available Anne Hutchinson lasciò l’Inghilterra nel 1634 per emigrare nel Massachusetts puritano, dove nel 1637 e 1638 fu processata, condannata, scomunicata ed espulsa come donna insubordinata, deviante e pericolosa. Il suo ruolo intellettuale e politico nell’alba incandescente della prima America viene qui analizzato e discusso ascoltando da presso il racconto che promana dalla voce della stessa Anne Hutchinson attraverso i verbali dei due processi, trascritti dai contemporanei con la fedeltà letterale che era tipica del puritanesimo americano. La drammatica controversia che ebbe al centro la presa di parola di questa donna segnò la prima grande crisi della neonata società coloniale – la cosiddetta crisi antinomiana -- e ne determinò gli sviluppi futuri, indirizzandoli verso un sistema di potere politico su basi teocratiche.

  8. Les premières années de The Himalayan Journal (1929-1940

    Directory of Open Access Journals (Sweden)

    Michel Raspaud

    2001-05-01

    Full Text Available IntroductionLa création de The Himalayan Club, sur le territoire de l’Empire des Indes à la fin de l’année 1927, s’accompagne presque aussitôt de la publication de The Himalayan Journal, en février 1929, soit mois de dix-huit mois après la création officielle de l’institution. L’objet du présent texte concerne donc la vie de The Himalayan Club lors de ses premières années d’existence, depuis la date de sa création jusqu’au début de la seconde guerre mondiale. Cependant, l’intérêt se focaliser...

  9. Development of an ANN optimized mucoadhesive buccal tablet containing flurbiprofen and lidocaine for dental pain.

    Science.gov (United States)

    Hussain, Amjad; Syed, Muhammad Ali; Abbas, Nasir; Hanif, Sana; Arshad, Muhammad Sohail; Bukhari, Nadeem Irfan; Hussain, Khalid; Akhlaq, Muhammad; Ahmad, Zeeshan

    2016-06-01

    A novel mucoadhesive buccal tablet containing flurbiprofen (FLB) and lidocaine HCl (LID) was prepared to relieve dental pain. Tablet formulations (F1-F9) were prepared using variable quantities of mucoadhesive agents, hydroxypropyl methyl cellulose (HPMC) and sodium alginate (SA). The formulations were evaluated for their physicochemical properties, mucoadhesive strength and mucoadhesion time, swellability index and in vitro release of active agents. Release of both drugs depended on the relative ratio of HPMC:SA. However, mucoadhesive strength and mucoadhesion time were better in formulations, containing higher proportions of HPMC compared to SA. An artificial neural network (ANN) approach was applied to optimise formulations based on known effective parameters (i.e., mucoadhesive strength, mucoadhesion time and drug release), which proved valuable. This study indicates that an effective buccal tablet formulation of flurbiprofen and lidocaine can be prepared via an optimized ANN approach.

  10. Development of an ANN optimized mucoadhesive buccal tablet containing flurbiprofen and lidocaine for dental pain

    Directory of Open Access Journals (Sweden)

    Hussain Amjad

    2016-06-01

    Full Text Available A novel mucoadhesive buccal tablet containing flurbiprofen (FLB and lidocaine HCl (LID was prepared to relieve dental pain. Tablet formulations (F1-F9 were prepared using variable quantities of mucoadhesive agents, hydroxypropyl methyl cellulose (HPMC and sodium alginate (SA. The formulations were evaluated for their physicochemical properties, mucoadhesive strength and mucoadhesion time, swellability index and in vitro release of active agents. Release of both drugs depended on the relative ratio of HPMC:SA. However, mucoadhesive strength and mucoadhesion time were better in formulations, containing higher proportions of HPMC compared to SA. An artificial neural network (ANN approach was applied to optimise formulations based on known effective parameters (i.e., mucoadhesive strength, mucoadhesion time and drug release, which proved valuable. This study indicates that an effective buccal tablet formulation of flurbiprofen and lidocaine can be prepared via an optimized ANN approach.

  11. A vitamini ve anne çocuk sağlığı Derleme

    OpenAIRE

    Günlemez, Ayla; Atasay, Begüm; Arsan, Saadet

    2014-01-01

    A vitamini normal görmede hücre farklılaşmasında çoğalmasında ve epitelial bütünlüğün sağlanmasında kritik rol oynar Gelişmekte olan ülkelerde A vitamini eksikliği önemli ve önlenebilir halk sağlığı sorunlarından biridir Bu makalede dünyada ve Türkiye’de A vitamini eksikliği ve anne çocuk sağlığı üzerine etkileri tartışılmaktadır Anahtar Kelimeler: A vitamini anne sağlığı çocuk sağlığıSummaryVitamin A has a critical role in normal vision cell differantiation proliferation and maintanence of e...

  12. Steni muinasjutuvõistluse võitjad selgunud / Ants Roos, Ann Roos

    Index Scriptorium Estoniae

    Roos, Ants

    2008-01-01

    Steni XVI muinasjutuvõistluse žüriisse kuulusid: Ann Roos, Ants Roos, Leelo Tungal, Krista Kumberg, Leida Olszak, Ülle Väljataga. Tulemused: I koht Siim Niinelaid, II koht Julius Air Kull, III koht Mihkel Rammu. Žürii eriauhinnad: Anna Kristin Peterson, Elis Ruus, Rain Hallikas, Mariliis Peterson, Marjaliisa Palu, Karl Kirsimäe, Margaret Pulk. Ergutusauhinnad: Karmel Klaus, Martti Kaljuste, Kristina Korell, Mirjam Võsaste, Mihkel Põder, Iirys Kalde, Miriam Jamul, Mari-Ann Mägi, Ketlin Saar, Liisbeth Kirss. Muud eriauhinnad said: Allan Läll, Berle Mees, Anett Kuuse, Karl Erik Kübarsepp, Grete Tamm, Siim Niinelaid, Kaisa Marie Sipelgas, Ellen Anett Põldmaa, Evelin Laul, Karl Laas, Karl Stamm, Kerli Retter

  13. Application of ann-based decision making pattern recognition to fishing operations

    Energy Technology Data Exchange (ETDEWEB)

    Akhlaghinia, M.; Torabi, F.; Wilton, R.R. [University of Regina, Saskatchewan (Canada). Faculty of Engineering. Dept. of Petroleum Engineering], e-mail: Farshid.Torabi@uregina.ca

    2010-10-15

    Decision making is a crucial part of fishing operations. Proper decisions should be made to prevent wasted time and associated costs on unsuccessful operations. This paper presents a novel model to help drilling managers decide when to commence and when to quit a fishing operation. A decision making model based on Artificial Neural Network (ANN) has been developed that utilizes Pattern Recognition based on 181 fishing incidents from one of the most fish-prone fields of the southwest of Iran. All parameters chosen to train the ANN-Based Pattern Recognition Tool are assumed to play a role in the success of the fishing operation and are therefore used to decide whether a fishing operation should be performed or not. If the tool deems the operation suitable for consideration, a cost analysis of the fishing operation can then be performed to justify its overall cost. (author)

  14. ANN based controller for three phase four leg shunt active filter for power quality improvement

    Directory of Open Access Journals (Sweden)

    J. Jayachandran

    2016-03-01

    Full Text Available In this paper, an artificial neural network (ANN based one cycle control (OCC strategy is proposed for the DSTATCOM shunted across the load in three phase four wire distribution system. The proposed control strategy mitigates harmonic/reactive currents, ensures balanced and sinusoidal source current from the supply mains that are nearly in phase with the supply voltage and compensates neutral current under varying source and load conditions. The proposed control strategy is superior over conventional methods as it eliminates, the sensors needed for sensing load current and coupling inductor current, in addition to the multipliers and the calculation of reference currents. ANN controllers are implemented to maintain voltage across the capacitor and as a compensator to compensate neutral current. The DSTATCOM performance is validated for all possible conditions of source and load by simulation using MATLAB software and simulation results prove the efficacy of the proposed control over conventional control strategy.

  15. Identification of Constitutive Parameters Using Inverse Strategy Coupled to an ANN Model

    International Nuclear Information System (INIS)

    Aguir, H.; Chamekh, A.; BelHadjSalah, H.; Hambli, R.

    2007-01-01

    This paper deals with the identification of material parameters using an inverse strategy. In the classical methods, the inverse technique is generally coupled with a finite element code which leads to a long computing time. In this work an inverse strategy coupled with an ANN procedure is proposed. This method has the advantage of being faster than the classical one. To validate this approach an experimental plane tensile and bulge tests are used in order to identify material behavior. The ANN model is trained from finite element simulations of the two tests. In order to reduce the gap between the experimental responses and the numerical ones, the proposed method is coupled with an optimization procedure to identify material parameters for the AISI304. The identified material parameters are the hardening curve and the anisotropic coefficients

  16. ANN-Benchmarks: A Benchmarking Tool for Approximate Nearest Neighbor Algorithms

    DEFF Research Database (Denmark)

    Aumüller, Martin; Bernhardsson, Erik; Faithfull, Alexander

    2017-01-01

    This paper describes ANN-Benchmarks, a tool for evaluating the performance of in-memory approximate nearest neighbor algorithms. It provides a standard interface for measuring the performance and quality achieved by nearest neighbor algorithms on different standard data sets. It supports several...... visualise these as images, Open image in new window plots, and websites with interactive plots. ANN-Benchmarks aims to provide a constantly updated overview of the current state of the art of k-NN algorithms. In the short term, this overview allows users to choose the correct k-NN algorithm and parameters...... for their similarity search task; in the longer term, algorithm designers will be able to use this overview to test and refine automatic parameter tuning. The paper gives an overview of the system, evaluates the results of the benchmark, and points out directions for future work. Interestingly, very different...

  17. Vegetarian Eco-feminist Consciousness in Carol Ann Duffy’s Poetry

    Directory of Open Access Journals (Sweden)

    Jie Zhou

    2015-07-01

    Full Text Available This paper discusses vegetarian eco-feminist consciousness in Carol Ann Duffy’s poetry by close analysis of two poems, namely “The Dolphins” and “A Healthy Diet” from her poem collection Standing Female Nude. The former is a dramatic monologue of a dolphin, which is exploited by people, and the latter is a dramatic monologue of an omnipotent observer in a restaurant. Both poems criticized the species-ism, and together, they showed the poet’s vegetarian eco-feminist consciousness. A close reading of the two poems from the eco-feminist perspective helps the reader understand why Carol Ann Duffy is honored as the first woman poet laureate in British history, and better understand vegetarian eco-feminism and its influence in British society. Keywords: eco-feminism; consciousness, species-ism, vegetarian, animal, diet

  18. Prophecy, patriarchy, and violence in the early modern household: the revelations of Anne Wentworth.

    Science.gov (United States)

    Johnston, Warren

    2009-10-01

    In 1676 the apostate Baptist prophet Anne Wentworth (1629/30-1693?) published "A True Account of Anne Wentworths Being Cruelly, Unjustly, and Unchristianly Dealt with by Some of Those People called Anabaptists," the first in a series of pamphlets that would continue to the end of the decade. Orignially a member of a London Baptist church, Wentworth left the congregation and eventually her own home after her husband used physical force to stop her writing and prophesying. Yet Wentworth persisted in her "revelations." These prophecies increasingly focused on her response to those who were trying to stop her efforts, especially within her own household. This article examines Wentworth's writings as an effort by an early modern woman, using arguments of spiritual agency, to assert ideas about proper gender roles and household responsibilities to denounce her husband and rebut those who criticized and attempted to suppress her.

  19. A Woman Voice in an Epic: Tracing Gendered Motifs in Anne Vabarna's Peko

    Directory of Open Access Journals (Sweden)

    Andreas Kalkun

    2008-12-01

    Full Text Available In the article the gendered motifs found in Anne Vabarna’s Seto epic Peko are analysed. Besides the narrative telling of the life of the male hero, the motives regarding eating, refusing to eat or offering food, and the aspect of the female body or its control deserve to be noticed. These scenes do not communicate the main plot, they are often related to minor characters of the epic and slow down the narrative, but at the same time they clearly carry artistic purpose and meaning. I consider these motifs, present in the liminal parts of the epic, to be the dominant symbols of the epic where the author’s feminine world is being exposed. Observing these motifs of Peko in the context of Seto religious worldview, the life of Anne Vabarna and the social position of Seto women, the symbols become eloquent and informative.

  20. FPGA implementation of adaptive ANN controller for speed regulation of permanent magnet stepper motor drives

    International Nuclear Information System (INIS)

    Hasanien, Hany M.

    2011-01-01

    This paper presents a novel adaptive artificial neural network (ANN) controller, which applies on permanent magnet stepper motor (PMSM) for regulating its speed. The dynamic response of the PMSM with the proposed controller is studied during the starting process under the full load torque and under load disturbance. The effectiveness of the proposed adaptive ANN controller is then compared with that of the conventional PI controller. The proposed methodology solves the problem of nonlinearities and load changes of PMSM drives. The proposed controller ensures fast and accurate dynamic response with an excellent steady state performance. Matlab/Simulink tool is used for this dynamic simulation study. The main contribution of this work is the implementation of the proposed controller on field programmable gate array (FPGA) hardware to drive the stepper motor. The driver is built on FPGA Spartan-3E Starter from Xilinx. Experimental results are presented to demonstrate the validity and effectiveness of the proposed control scheme.

  1. Development of wavelet-ANN models to predict water quality parameters in Hilo Bay, Pacific Ocean.

    Science.gov (United States)

    Alizadeh, Mohamad Javad; Kavianpour, Mohamad Reza

    2015-09-15

    The main objective of this study is to apply artificial neural network (ANN) and wavelet-neural network (WNN) models for predicting a variety of ocean water quality parameters. In this regard, several water quality parameters in Hilo Bay, Pacific Ocean, are taken under consideration. Different combinations of water quality parameters are applied as input variables to predict daily values of salinity, temperature and DO as well as hourly values of DO. The results demonstrate that the WNN models are superior to the ANN models. Also, the hourly models developed for DO prediction outperform the daily models of DO. For the daily models, the most accurate model has R equal to 0.96, while for the hourly model it reaches up to 0.98. Overall, the results show the ability of the model to monitor the ocean parameters, in condition with missing data, or when regular measurement and monitoring are impossible. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Theory Study and Application of the BP-ANN Method for Power Grid Short-Term Load Forecasting

    Institute of Scientific and Technical Information of China (English)

    Xia Hua; Gang Zhang; Jiawei Yang; Zhengyuan Li

    2015-01-01

    Aiming at the low accuracy problem of power system short⁃term load forecasting by traditional methods, a back⁃propagation artifi⁃cial neural network (BP⁃ANN) based method for short⁃term load forecasting is presented in this paper. The forecast points are re⁃lated to prophase adjacent data as well as the periodical long⁃term historical load data. Then the short⁃term load forecasting model of Shanxi Power Grid (China) based on BP⁃ANN method and correlation analysis is established. The simulation model matches well with practical power system load, indicating the BP⁃ANN method is simple and with higher precision and practicality.

  3. Prediction of Tourism Demand in Iran by Using Artificial Neural Network (ANN and Supporting Vector Machine (SVR

    Directory of Open Access Journals (Sweden)

    Seyedehelham Sadatiseyedmahalleh

    2016-02-01

    Full Text Available This research examines and proves this effectiveness connected with artificial neural networks (ANNs as an alternative approach to the use of Support Vector Machine (SVR in the tourism research. This method can be used for the tourism industry to define the turism’s demands in Iran. The outcome reveals the use of ANNs in tourism research might result in better quotations when it comes to prediction bias and accuracy. Even more applications of ANNs in the context of tourism demand evaluation is needed to establish and validate the effects.

  4. Establishment and extinction of a population of South Georgian diving petrel (Pelecanoides georgicus) at Mason Bay, Stewart Island, New Zealand, during the late Holocene

    International Nuclear Information System (INIS)

    Holdaway, R.N.; Jones, M.D.; Beavan Athfield, N.R.

    2003-01-01

    A population of South Georgian diving petrels (Pelecanoides georgicus) (c. 130 g) became extinct at Mason Bay, on the west coast of Stewart Island, before European settlement. Pacific rat (Rattus exulans) bones with the diving petrel fossils provided an opportunity to determine whether the rats arrived before the petrels went extinct. Fifteen 14 C accelerator mass spectrometry (AMS) ages on purified diving petrel bone gelatin from various parts of Mason Bay clustered unexpectedly in the 14th and 15th centuries AD, and none was older. Bayesian statistical analysis, using a Markov Chain Monte Carlo procedure, gave a 95% probability that the diving petrel colony was founded between 1338 and 1440 AD, lasted 40-310 years, and became extinct between 1475 and 1650 AD. Possible reasons for the late colonisation of Mason Bay by South Georgian diving petrels burrow are discussed. Bayesian analysis of five 14 C AMS determinations on Pacific rat bone gelatin did not exclude the possibility that the Pacific rat arrived before the diving petrel colony was established. However, the enriched δ 13 C of their bone gelatin suggests that the rats had a partially marine diet, and a terrestrial calibration procedure for their AMS ages was probably not appropriate. The Pacific rat is likely to have arrived after the diving petrel colony became established and probably caused the bird's extinction after a short period of coexistence. (author). 103 refs., 3 figs., 5 tabs

  5. [The embroidery work of the lady at Saint-Anne Hospital].

    Science.gov (United States)

    Thillaud, Pierre L; Postel, Jacques

    2014-01-01

    In July 1974, a 72 old woman had been a patient for forty years in Sainte-Anne Hospital, Ward C. As she had again a violent brawl with her neighbour patient, she revealed being a tremendous artist. She had been confined on account of dementia paralytica in the Mecca of malariotherapy, and passionately devoted herself to embroidery. Her fancy work was rather a matter for Jean Dubuffet's art through its perfect expression and deserved being known.

  6. 'In the developed world, people talk and shop'- a review by Anne ...

    African Journals Online (AJOL)

    'In the developed world, people talk and shop'- a review by Anne Derges. A. Salleh. http://dx.doi.org/10.4314/safere.v3i1.23966 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL ...

  7. Prediction of groundwater levels from lake levels and climate data using ANN approach

    OpenAIRE

    Dogan, Ahmet; Demirpence, Husnu; Cobaner, Murat

    2008-01-01

    There are many environmental concerns relating to the quality and quantity of surface and groundwater. It is very important to estimate the quantity of water by using readily available climate data for managing water resources of the natural environment. As a case study an artificial neural network (ANN) methodology is developed for estimating the groundwater levels (upper Floridan aquifer levels) as a function of monthly averaged precipitation, evaporation, and measured levels of Magnolia an...

  8. Assessing the Long Term Impact of Phosphorus Fertilization on Phosphorus Loadings Using AnnAGNPS

    OpenAIRE

    Yuan, Yongping; Bingner, Ronald L.; Locke, Martin A.; Stafford, Jim; Theurer, Fred D.

    2011-01-01

    High phosphorus (P) loss from agricultural fields has been an environmental concern because of potential water quality problems in streams and lakes. To better understand the process of P loss and evaluate the effects of different phosphorus fertilization rates on phosphorus losses, the USDA Annualized AGricultural Non-Point Source (AnnAGNPS) pollutant loading model was applied to the Ohio Upper Auglaize watershed, located in the southern portion of the Maumee River Basin. In this study, the ...

  9. Implementation of ANN on CCHP system to predict trigeneration performance with consideration of various operative factors

    International Nuclear Information System (INIS)

    Anvari, Simin; Taghavifar, Hadi; Saray, Rahim Khoshbakhti; Khalilarya, Shahram; Jafarmadar, Samad

    2015-01-01

    Highlights: • ANN modeling tool was implemented on the CCHP system. • The best ANN topology was detected 10–8–9 with Levenberg–Marquadt algorithm. • The system is more sensitive of CC outlet temperature and turbine isentropic efficiency. • The lowest RMSE = 3.13e−5 and the best R 2 = 0.999 is related to lambda and second law efficiency terms, respectively. - Abstract: A detailed investigation was aimed based on numerical thermodynamic survey and artificial neural network (ANN) modeling of the trigeneration system. The results are presented in two pivotal frameworks namely the sensitivity analysis and ANN prediction capability of proposed modeling. The underlying operative parameters were chosen as input parameters from different cycles and components, while the exergy efficiency, exergy loss, coefficient of performance, heating load exergy, lambda, gas turbine power, exergy destruction, actual outlet air compressor temperature, and heat recovery gas steam generator (HRSG) outlet temperature were taken as objective output parameters for the modeling purpose. Up to now, no significant step was taken to investigate the compound power plant with thermodynamic analyses and network predictability hybrid in such a detailed oriented approach. It follows that multilayer perceptron neural network with back propagation algorithm deployed with 10–8–9 configuration results in the modeling reliability ranged within R 2 = 0.995–0.999. When dataset treated with trainlm learning algorithm and diversified neurons, the mean square error (MSE) is obtained equal to 0.2175. This denotes a powerful modeling achievement in both scientific and industrial scale to save considerable computational cost on combined cooling, heating, and power system in accomplishment of boosting the energy efficiency and system maintenance

  10. Data-Driven Modeling of Complex Systems by means of a Dynamical ANN

    Science.gov (United States)

    Seleznev, A.; Mukhin, D.; Gavrilov, A.; Loskutov, E.; Feigin, A.

    2017-12-01

    The data-driven methods for modeling and prognosis of complex dynamical systems become more and more popular in various fields due to growth of high-resolution data. We distinguish the two basic steps in such an approach: (i) determining the phase subspace of the system, or embedding, from available time series and (ii) constructing an evolution operator acting in this reduced subspace. In this work we suggest a novel approach combining these two steps by means of construction of an artificial neural network (ANN) with special topology. The proposed ANN-based model, on the one hand, projects the data onto a low-dimensional manifold, and, on the other hand, models a dynamical system on this manifold. Actually, this is a recurrent multilayer ANN which has internal dynamics and capable of generating time series. Very important point of the proposed methodology is the optimization of the model allowing us to avoid overfitting: we use Bayesian criterion to optimize the ANN structure and estimate both the degree of evolution operator nonlinearity and the complexity of nonlinear manifold which the data are projected on. The proposed modeling technique will be applied to the analysis of high-dimensional dynamical systems: Lorenz'96 model of atmospheric turbulence, producing high-dimensional space-time chaos, and quasi-geostrophic three-layer model of the Earth's atmosphere with the natural orography, describing the dynamics of synoptical vortexes as well as mesoscale blocking systems. The possibility of application of the proposed methodology to analyze real measured data is also discussed. The study was supported by the Russian Science Foundation (grant #16-12-10198).

  11. Modelling the spectral irradiance distribution in sunny inland locations using an ANN-based methodology

    International Nuclear Information System (INIS)

    Torres-Ramírez, M.; Elizondo, D.; García-Domingo, B.; Nofuentes, G.; Talavera, D.L.

    2015-01-01

    This work is aimed at verifying that in sunny inland locations artificial intelligence techniques may provide an estimation of the spectral irradiance with adequate accuracy for photovoltaic applications. An ANN (artificial neural network) based method was developed, trained and tested to model the spectral distributions between wavelengths ranging from 350 to 1050 nm. Only commonly available input data such as geographical information regarding location, specific date and time together with horizontal global irradiance and ambient temperature are required. Historical information from a 24-month experimental campaign carried out in Jaén (Spain) provided the necessary data to train and test the ANN tool. A Kohonen self-organized map was used as innovative technique to classify the whole input dataset and build a small and representative training dataset. The shape of the spectral irradiance distribution, the in-plane global irradiance (G T ) and irradiation (H T ) and the APE (average photon energy) values obtained through the ANN method were statistically compared to the experimental ones. In terms of shape distribution fitting, the mean relative deformation error stays below 4.81%. The root mean square percentage error is around 6.89% and 0.45% when estimating G T and APE, respectively. Regarding H T , errors lie below 3.18% in all cases. - Highlights: • ANN-based model to estimate the spectral irradiance distribution in sunny inland locations. • MRDE value stay below 4.81% in spectral irradiance distribution shape fitting. • RMSPE is about 6.89% for the in-plane global irradiance and 0.45% for the average photon energy. • Errors stay below 3.18% for all the months of the year in incident irradiation terms. • Improvement of assessment of the impact of the solar spectrum in the performance of a PV module

  12. Rapport de frais de 2017-2018 pour Mary Anne Chambers | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Rapport de frais de 2017-2018 pour Mary Anne Chambers. Total des frais de déplacement : CAD$17,362.55. Réunion du Conseil des gouverneurs. 19 novembre 2017 au 24 novembre 2017. CAD$2,185.41. Réunions au CRDI 1 novembre 2017 CAD$714.15. Constatation de l'impact de la recherche en Afrique de l'Est.

  13. Flora pteridofítica de fragmentos florestais do Parque Estadual de Vassununga – Santa Rita do Passa Quatro, SP. Pteridophyte flora of forest fragments in Vassununga State Park – Santa Rita do Passa Quatro, São Paulo, Brazil.

    Directory of Open Access Journals (Sweden)

    Áurea Maria Therezinha COLLI

    2014-06-01

    Full Text Available Este trabalho apresenta o levantamento da flora pteridofítica de dois fragmentos florestais do Parque Estadual de Vassununga, unidade de conservação localizada no município de Santa Rita do Passa Quatro, SP. Para tanto, foram realizadas onze excursões por caminhos e trilhas de fiscalização e de pesquisa. Na Gleba Maravilha, que apresenta vegetação de Floresta Estacional Semidecidual Montana e Floresta Estacional Semidecidual Aluvial com inundação temporária, foram encontradas 10 famílias, 18 gêneros e 35 espécies, sendo Pteridaceae, Thelypteridaceae, Aspleniaceae, e Polypodiaceae as famílias mais ricas com nove, sete, seis e cinco espécies, respectivamente. Na Gleba Capão da Várzea, onde ocorre a Floresta Paludosa e o Campo Antrópico, ocorreram nove famílias, 14 gêneros e 24 espécies, onde Thelypteridaceae e Polypodiaceae se apresentaram como as mais ricas, com oito e seis espécies, respectivamente. As Glebas do Parque Estadual de Vassununga com as suas diferentes fisionomias vegetais são áreas importantes para a conservação de pteridófitas na região nordeste do Estado de São Paulo, principalmente as típicas de Floresta Estacional Semidecidual Montana e de Floresta Paludosa como Blechnum brasiliense, Campyloneurum angustifolium, Cyclodium meniscioides, Osmunda regalis, Pityrogramma calomelanos e Thelypteris opposita. This work presents a survey on pteridophyte flora of two forest fragments in Vassununga State Park, a conservation unit located in the city of Santa Rita do Passa Quatro, São Paulo, Brazil. In order to carry out the survey, a series of eleven tours on old inspection and research trails were made. In the Maravilha Tract, which consists of Seasonal Semi-Deciduous Montane Forest and Seasonal Semideciduous Alluvial Forest with temporary flooding, 10 families, 18 genera, and 35 species were found, the richest families were Pteridaceae, Thelypteridaceae, Aspleniaceae, and Polypodiaceae, with nine, seven

  14. Pteridófitas do Parque Estadual de Vassununga, Santa Rita do Passa Quatro (SP, Brasil. Gleba Pé-de-Gigante. Pteridophytes from Vassununga State Park, Santa Rita do Passa Quatro, SP, Brazil. Gleba Pé-de-Gigante.

    Directory of Open Access Journals (Sweden)

    Áurea Maria Therezinha COLLI

    2004-12-01

    Full Text Available Neste trabalho foi realizado um levantamentode pteridófitas na Gleba Pé-de-Gigante do ParqueEstadual de Vassununga, localizado no municípiode Santa Rita do Passa Quatro, sob as coordenadas21º36’39,01054’’S e 47º37’03,46727’’W. As coletasforam realizadas em três trilhas, denominadasTrilha do Meliponário, Trilha do Córrego Paulicéiae Trilha da Torre. Foram reconhecidas 15 espéciesde pteridófitas pertencentes a 7 famílias. Dessas,as mais representativas foram Polypodiaceae eThelypteridaceae com quatro espécies cada,e Pteridaceae e Schizaeaceae que apresentaramduas espécies cada. Das 15 espécies registradas9 apresentam distribuição bastante restrita, ocorrendoapenas na Trilha do Córrego Paulicéia. Por outrolado, Microgramma squamulosa (Kaulf. de laSota, Pleopeltis angusta Willd e Polypodiumpolypodioides (L. Watt são as espécies deocorrência mais ampla. Em todas as trilhas hápteridófitas, sendo que a Trilha do CórregoPaulicéia é a mais rica, e a Trilha da Torre a maispobre em número de espécies. As pteridófitasocorrem no cerrado “sensu stricto”, cerradão e nafloresta de galeria. A maior diversidade de espéciesfoi encontrada na floresta de galeria.This work presents a pteridophyticalsurvey carried out at the Gleba Pé-de-Gigante ofthe Vassununga State Park, in the municipality ofSanta Rita do Passa Quatro (21º36’39.01054’’Sand 47º37’03.46727’’W. Collections wereaccomplished at three trails called “Trilha doMeliponário, Trilha do Córrego Paulicéia andTrilha da Torre ”. Fifteen species of pteridophytespertaining to 7 families were recognized. From these,the most representative ones were Polypodiaceaeand Thelypteridaceae, with 4 species each, andPteridaceae and Schizaeaceae, with two specieseach. From the 15 species registered, nine present avery restricted distribution occurring only in the“Trilha do Córrego Paulic��ia”, Microgrammasquamulosa, Pleopeltis angusta and

  15. Pteridófitas do Parque Estadual da Vassununga, Santa Rita do Passa Quatro (SP, Brasil. Glebas Capetinga Leste e Capetinga Oeste. Pteridophytes from Vassununga State Park, Santa Rita do Passa Quatro, SP, Brazil. Glebas Capetinga Leste and Capetinga Oeste.

    Directory of Open Access Journals (Sweden)

    Áurea Maria Therezinha COLLI

    2004-06-01

    Full Text Available Neste trabalho foi realizado umlevantamento de pteridófitas nas Glebas CapetingaLeste e Capetinga Oeste do Parque Estadual daVassununga, localizado no município de Santa Rita doPassa Quatro, sob as coordenadas 21º41’00’’ –21º41’21’’S e 47º34’37’’ – 47º39’39’’W. As coletasforam realizadas em quatro trilhas, denominadasTrilha da Mina, Trilha do Ribeirão Bebedouro,Trilha dos Jequitibás e Trilha do Córrego da Gruta.Foram reconhecidas 34 espécies de pteridófitaspertencentes a 10 famílias. Destas, as maisrepresentativas foram Polypodiaceae e Thelypteridaceaecom seis espécies cada e Aspleniaceae e Pteridaceaeque apresentaram cinco espécies cada. Das 34espécies registradas 10 apresentam distribuiçãobastante restrita, ocorrendo apenas na Trilha da Mina.Por outro lado, Polypodium polypodioides (L. Watt,Pteris denticulata var. denticulata Sw eThelypteris dentata (Forssk. E. St. John são asespécies de ocorrência mais ampla. Em todas astrilhas há pteridófitas, sendo que a Trilha da Minaé a mais rica e a Trilha do Ribeirão Bebedouro amais pobre em número de espécies. As pteridófitasocorrem na floresta estacional semidecidual e namata ciliar. A maior diversidade de espécies foiencontrada na floresta estacional semidecidual.This work presents a pteridophyticalsurvey carried out at Glebas Capetinga Leste andCapetinga Oeste at Vassununga State Park,Santa Rita do Passa Quatro county, (21º41’00’’ –21º41’21’’S and 47º34’37’’ – 47º39’39’’W.Collections were done at four places called “Trilhada Mina”, “Trilha do Ribeirão Bebedouro”, “Trilhados Jequitibás” and “Trilha do Córrego da Gruta.”Thirty-four species of pteridophytes pertaining to10 families were recognized. Among them, themost representative ones were Polypodiaceaeand Thelypteridaceae, with six species each,and Aspleniaceae and Pteridaceae, with fivespecies each. Considering the 34 species registered,10

  16. Predicting the Deflections of Micromachined Electrostatic Actuators Using Artificial Neural Network (ANN

    Directory of Open Access Journals (Sweden)

    Hing Wah LEE

    2009-03-01

    Full Text Available In this study, a general purpose Artificial Neural Network (ANN model based on the feed-forward back-propagation (FFBP algorithm has been used to predict the deflections of a micromachined structures actuated electrostatically under different loadings and geometrical parameters. A limited range of simulation results obtained via CoventorWare™ numerical software will be used initially to train the neural network via back-propagation algorithm. The micromachined structures considered in the analyses are diaphragm, fixed-fixed beams and cantilevers. ANN simulation results are compared with results obtained via CoventorWare™ simulations and existing analytical work for validation purpose. The proposed ANN model accurately predicts the deflections of the micromachined structures with great reduction of simulation efforts, establishing the method superiority. This method can be extended for applications in other sensors particularly for modeling sensors applying electrostatic actuation which are difficult in nature due to the inherent non-linearity of the electro-mechanical coupling response.

  17. ANN based Performance Evaluation of BDI for Condition Monitoring of Induction Motor Bearings

    Science.gov (United States)

    Patel, Raj Kumar; Giri, V. K.

    2017-06-01

    One of the critical parts in rotating machines is bearings and most of the failure arises from the defective bearings. Bearing failure leads to failure of a machine and the unpredicted productivity loss in the performance. Therefore, bearing fault detection and prognosis is an integral part of the preventive maintenance procedures. In this paper vibration signal for four conditions of a deep groove ball bearing; normal (N), inner race defect (IRD), ball defect (BD) and outer race defect (ORD) were acquired from a customized bearing test rig, under four different conditions and three different fault sizes. Two approaches have been opted for statistical feature extraction from the vibration signal. In the first approach, raw signal is used for statistical feature extraction and in the second approach statistical features extracted are based on bearing damage index (BDI). The proposed BDI technique uses wavelet packet node energy coefficients analysis method. Both the features are used as inputs to an ANN classifier to evaluate its performance. A comparison of ANN performance is made based on raw vibration data and data chosen by using BDI. The ANN performance has been found to be fairly higher when BDI based signals were used as inputs to the classifier.

  18. Numerical weather prediction (NWP) and hybrid ARMA/ANN model to predict global radiation

    International Nuclear Information System (INIS)

    Voyant, Cyril; Muselli, Marc; Paoli, Christophe; Nivet, Marie-Laure

    2012-01-01

    We propose in this paper an original technique to predict global radiation using a hybrid ARMA/ANN model and data issued from a numerical weather prediction model (NWP). We particularly look at the multi-layer perceptron (MLP). After optimizing our architecture with NWP and endogenous data previously made stationary and using an innovative pre-input layer selection method, we combined it to an ARMA model from a rule based on the analysis of hourly data series. This model has been used to forecast the hourly global radiation for five places in Mediterranean area. Our technique outperforms classical models for all the places. The nRMSE for our hybrid model MLP/ARMA is 14.9% compared to 26.2% for the naïve persistence predictor. Note that in the standalone ANN case the nRMSE is 18.4%. Finally, in order to discuss the reliability of the forecaster outputs, a complementary study concerning the confidence interval of each prediction is proposed. -- Highlights: ► Time series forecasting with hybrid method based on the use of ALADIN numerical weather model, ANN and ARMA. ► Innovative pre-input layer selection method. ► Combination of optimized MLP and ARMA model obtained from a rule based on the analysis of hourly data series. ► Stationarity process (method and control) for the global radiation time series.

  19. Evaluation of Effectiveness of Wavelet Based Denoising Schemes Using ANN and SVM for Bearing Condition Classification

    Directory of Open Access Journals (Sweden)

    Vijay G. S.

    2012-01-01

    Full Text Available The wavelet based denoising has proven its ability to denoise the bearing vibration signals by improving the signal-to-noise ratio (SNR and reducing the root-mean-square error (RMSE. In this paper seven wavelet based denoising schemes have been evaluated based on the performance of the Artificial Neural Network (ANN and the Support Vector Machine (SVM, for the bearing condition classification. The work consists of two parts, the first part in which a synthetic signal simulating the defective bearing vibration signal with Gaussian noise was subjected to these denoising schemes. The best scheme based on the SNR and the RMSE was identified. In the second part, the vibration signals collected from a customized Rolling Element Bearing (REB test rig for four bearing conditions were subjected to these denoising schemes. Several time and frequency domain features were extracted from the denoised signals, out of which a few sensitive features were selected using the Fisher’s Criterion (FC. Extracted features were used to train and test the ANN and the SVM. The best denoising scheme identified, based on the classification performances of the ANN and the SVM, was found to be the same as the one obtained using the synthetic signal.

  20. Comparing SVM and ANN based Machine Learning Methods for Species Identification of Food Contaminating Beetles.

    Science.gov (United States)

    Bisgin, Halil; Bera, Tanmay; Ding, Hongjian; Semey, Howard G; Wu, Leihong; Liu, Zhichao; Barnes, Amy E; Langley, Darryl A; Pava-Ripoll, Monica; Vyas, Himansu J; Tong, Weida; Xu, Joshua

    2018-04-25

    Insect pests, such as pantry beetles, are often associated with food contaminations and public health risks. Machine learning has the potential to provide a more accurate and efficient solution in detecting their presence in food products, which is currently done manually. In our previous research, we demonstrated such feasibility where Artificial Neural Network (ANN) based pattern recognition techniques could be implemented for species identification in the context of food safety. In this study, we present a Support Vector Machine (SVM) model which improved the average accuracy up to 85%. Contrary to this, the ANN method yielded ~80% accuracy after extensive parameter optimization. Both methods showed excellent genus level identification, but SVM showed slightly better accuracy  for most species. Highly accurate species level identification remains a challenge, especially in distinguishing between species from the same genus which may require improvements in both imaging and machine learning techniques. In summary, our work does illustrate a new SVM based technique and provides a good comparison with the ANN model in our context. We believe such insights will pave better way forward for the application of machine learning towards species identification and food safety.