WorldWideScience

Sample records for risk evaluation risk

  1. Judging risk behaviour and risk preference: the role of the evaluative connotation of risk terms.

    NARCIS (Netherlands)

    van Schie, E.C.M.; van der Pligt, J.; van Baaren, K.

    1993-01-01

    Two experiments investigated the impact of the evaluative connotation of risk terms on the judgment of risk behavior and on risk preference. Exp 1 focused on the evaluation congruence of the risk terms with a general risk norm and with Ss' individual risk preference, and its effects on the extremity

  2. Risk estimation and evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Ferguson, R A.D.

    1982-10-01

    Risk assessment involves subjectivity, which makes objective decision making difficult in the nuclear power debate. The author reviews the process and uncertainties of estimating risks as well as the potential for misinterpretation and misuse. Risk data from a variety of aspects cannot be summed because the significance of different risks is not comparable. A method for including political, social, moral, psychological, and economic factors, environmental impacts, catastrophes, and benefits in the evaluation process could involve a broad base of lay and technical consultants, who would explain and argue their evaluation positions. 15 references. (DCK)

  3. Evaluations and utilizations of risk importances

    International Nuclear Information System (INIS)

    Vesely, W.E.; Davis, T.C.

    1985-08-01

    This report presents approaches for utilizing Probabilistic Risk Analyses (PRA's) to determine risk importances. Risk importances are determined for design features, plant operations, and other factors that can affect risk. PRA's can be used to identify the importances of risk contributors or proposed changes to designs or operations. The objective of this report is to serve as a handbook and guide in evaluating and applying risk importances. The utilization of both qualitative risk importances and quantitative risk importances is described in this report. Qualitative risk importances are based on the logic models in the PRA, while quantitative risk importances are based on the quantitative results of the PRA. Both types of importances are among the most robust and meaningful information a PRA can provide. A wide variety of risk importance evaluations are described including evaluations of the importances of design changes, testing, maintenance, degrading environments, and aging. Specific utilizations are described in inspection and in reliability assurance programs, however the general approaches have widespread applicability. The role of personal computers and decision support programs in applying risk importance evaluations is also described

  4. HOW INTERNAL RISK - BASED AUDIT APPRAISES THE EVALUATION OF RISKS MANAGEMENT

    Directory of Open Access Journals (Sweden)

    N. Dorosh

    2017-09-01

    Full Text Available The article deals with the nature and function of the internal risk-based audit process approach to create patterns of risks and methods of evaluation. Deals with the relationship between the level of maturity of the risk of the company and the method of risk-based internal audit. it was emphasized that internal auditing provides an independent and objective opinion to an organization’s management as to whether its risks are being managed to acceptable levels.

  5. Screening Risk Evaluation methodology

    International Nuclear Information System (INIS)

    Hopper, K.M.

    1994-01-01

    The Screening Risk Evaluation (SRE) Guidance document is a set of guidelines provided for the uniform implementation of SREs performed on D ampersand D facilities. These guidelines are designed specifically for the completion of the second (semi-quantitative screening) phase of the D ampersand D Risk-Based Process. The SRE Guidance produces screening risk scores reflecting levels of risk through the use of risk ranking indices. Five types of possible risk are calculated from the SRE: current releases, worker exposures, future releases, physical hazards, and criticality. The Current Release Index (CRI) calculates the risk to human health and the environment from ongoing or probable releases within a one year time period. The Worker Exposure Index (WEI) calculates the risk to workers, occupants, and visitors in D ampersand D facilities of contaminant exposure. The Future Release Index (FRI) calculates the risk of future releases of contaminants, after one year, to human health and the environment. The Physical Hazards Index (PHI) calculates the risk-to human health due to factors other than that of contaminants. The index of Criticality is approached as a modifying factor to the entire SRE, due to the fact that criticality issues are strictly regulated under DOE. Screening risk results will be tabulated in matrix form and Total Risk will be calculated (weighted equation) to produce a score on which to base early action recommendations. Other recommendations from the screening risk scores will be made based either on individual index scores or from reweighted Total Risk calculations. All recommendations based on the SRE will be made based on a combination of screening risk scores, decision drivers, and other considerations, determined on a project by project basis. The SRE is the first and most important step in the overall D ampersand D project level decision making process

  6. Credit Risk Evaluation : Modeling - Analysis - Management

    OpenAIRE

    Wehrspohn, Uwe

    2002-01-01

    An analysis and further development of the building blocks of modern credit risk management: -Definitions of default -Estimation of default probabilities -Exposures -Recovery Rates -Pricing -Concepts of portfolio dependence -Time horizons for risk calculations -Quantification of portfolio risk -Estimation of risk measures -Portfolio analysis and portfolio improvement -Evaluation and comparison of credit risk models -Analytic portfolio loss distributions The thesis contributes to the evaluatio...

  7. Ethical and affective evaluation of environmental risks

    International Nuclear Information System (INIS)

    Bohm, G.; Pfister, H.R.

    1998-01-01

    Full text of publication follows: the present paper will be concerned with environmental risk perception, with special emphasis on those environmental risks that pertain to global change phenomena, such as climate change and ozone depletion. Two determinants of risk judgments are investigated that seem particularly relevant to environmental risks: ethical and affective evaluations. It is assumed that the focus of risk evaluation can be on one of two aspects: a) on an evaluation of potential losses, or b) on ethical considerations. We assume that both, potential loss and violation of ethical principles elicit emotional evaluations, but that these two judgmental aspects are associated with different specific emotions. Following cognitive emotion theories, we distinguish loss-based emotions, such as worry and fear, from ethical emotions, e.g., guilt and anger. A study is presented that investigates the role of ethical and affective evaluations in risk judgments. Various environmental risks were presented to subjects, e.g., air pollution, ozone depletion, climate change and destruction of ecological balance. For each environmental risk, subjects indicated in free-response format as well as on rating scales the extent to which ethical principles were violated, and the intensity of both loss-based and ethical emotions. The correlational structure of the emotion ratings confirms the distinction between loss-based and ethical emotions. Risk judgments co-vary with the strength of ethical evaluation and with the intensity of loss-based emotions, but are independent of ethical emotions. The implications of these findings for the risk appraisal process are discussed. (authors)

  8. Issues in Value-at-Risk Modeling and Evaluation

    NARCIS (Netherlands)

    J. Daníelsson (Jón); C.G. de Vries (Casper); B.N. Jorgensen (Bjørn); P.F. Christoffersen (Peter); F.X. Diebold (Francis); T. Schuermann (Til); J.A. Lopez (Jose); B. Hirtle (Beverly)

    1998-01-01

    textabstractDiscusses the issues in value-at-risk modeling and evaluation. Value of value at risk; Horizon problems and extreme events in financial risk management; Methods of evaluating value-at-risk estimates.

  9. Risk effectiveness evaluation of surveillance testing

    International Nuclear Information System (INIS)

    Kim, I.S.; Samanta, P.K.; Martorell, S.; Vesely, W.E.

    1991-01-01

    To address the concerns about nuclear power plant surveillance tests, i.e., their adverse safety impact due to negative effects and too burdensome requirements, it is necessary to evaluate the safety significance or risk effectiveness of such tests explicitly considering both negative and positive effects. This paper defines the negative effects of surveillance testing from a risk perspective, and then presents a methodology to quantify the negative risk impact, i.e., the risk penalty or risk increase caused by the test. The method focuses on two important kinds of negative effects, namely, test-caused transients and test-caused equipment degradations. The concepts and quantitative methods for the risk evaluation can be used in the decision-making process to establish the safety significance of the tests and to screen the plant-specific surveillance test requirements. 6 refs., 2 figs., 2 tabs

  10. Evaluation of the Prostate Cancer Prevention Trial Risk Calculator in a High-Risk Screening Population

    Science.gov (United States)

    Kaplan, David J.; Boorjian, Stephen A.; Ruth, Karen; Egleston, Brian L.; Chen, David Y.T.; Viterbo, Rosalia; Uzzo, Robert G.; Buyyounouski, Mark K.; Raysor, Susan; Giri, Veda N.

    2009-01-01

    Introduction Clinical factors in addition to PSA have been evaluated to improve risk assessment for prostate cancer. The Prostate Cancer Prevention Trial (PCPT) risk calculator provides an assessment of prostate cancer risk based on age, PSA, race, prior biopsy, and family history. This study evaluated the risk calculator in a screening cohort of young, racially diverse, high-risk men with a low baseline PSA enrolled in the Prostate Cancer Risk Assessment Program. Patients and Methods Eligibility for PRAP include men ages 35-69 who are African-American, have a family history of prostate cancer, or have a known BRCA1/2 mutation. PCPT risk scores were determined for PRAP participants, and were compared to observed prostate cancer rates. Results 624 participants were evaluated, including 382 (61.2%) African-American men and 375 (60%) men with a family history of prostate cancer. Median age was 49.0 years (range 34.0-69.0), and median PSA was 0.9 (range 0.1-27.2). PCPT risk score correlated with prostate cancer diagnosis, as the median baseline risk score in patients diagnosed with prostate cancer was 31.3%, versus 14.2% in patients not diagnosed with prostate cancer (p<0.0001). The PCPT calculator similarly stratified the risk of diagnosis of Gleason score ≥7 disease, as the median risk score was 36.2% in patients diagnosed with Gleason ≥7 prostate cancer versus 15.2% in all other participants (p<0.0001). Conclusion PCPT risk calculator score was found to stratify prostate cancer risk in a cohort of young, primarily African-American men with a low baseline PSA. These results support further evaluation of this predictive tool for prostate cancer risk assessment in high-risk men. PMID:19709072

  11. A Fuzzy Comprehensive Evaluation Model for Sustainability Risk Evaluation of PPP Projects

    Directory of Open Access Journals (Sweden)

    Libiao Bai

    2017-10-01

    Full Text Available Evaluating the sustainability risk level of public–private partnership (PPP projects can reduce project risk incidents and achieve the sustainable development of the organization. However, the existing studies about PPP projects risk management mainly focus on exploring the impact of financial and revenue risks but ignore the sustainability risks, causing the concept of “sustainability” to be missing while evaluating the risk level of PPP projects. To evaluate the sustainability risk level and achieve the most important objective of providing a reference for the public and private sectors when making decisions on PPP project management, this paper constructs a factor system of sustainability risk of PPP projects based on an extensive literature review and develops a mathematical model based on the methods of fuzzy comprehensive evaluation model (FCEM and failure mode, effects and criticality analysis (FMECA for evaluating the sustainability risk level of PPP projects. In addition, this paper conducts computational experiment based on a questionnaire survey to verify the effectiveness and feasibility of this proposed model. The results suggest that this model is reasonable for evaluating the sustainability risk level of PPP projects. To our knowledge, this paper is the first study to evaluate the sustainability risk of PPP projects, which would not only enrich the theories of project risk management, but also serve as a reference for the public and private sectors for the sustainable planning and development. Keywords: sustainability risk eva

  12. Overall strategy for risk evaluation and priority setting of risk regulations

    International Nuclear Information System (INIS)

    Hokstad, Per; Steiro, Trygve

    2006-01-01

    This paper presents the framework of an approach to support planning and priority setting for risk control. Such an approach could assist government/regulatory authorities in their allocation of resources among different sectors. The term risk will here be used in a very wide sense, and it will include, but not restrict to, the traditional HES (Health, Environment and Safety) concept. An overall classification of risk ('loss categories'), to be used across sectors and directorates is suggested. The risk evaluation includes a number of factors not accounted for in a standard risk assessment, but should be taken into account when authorities set priorities regarding risk control. Sociological, psychological and ethical perspectives are included, and the need for a discourse during the decision process is pinpointed. The paper also discusses the potential inclusion of cost benefit analyses in such an approach. The indicated approach is denoted Risk Across Sectors (RAS), and suggestions regarding the process to implement it are given. Such an implementation process will by itself increase the knowledge and competence of the involved parties

  13. Modified risk evaluation method

    International Nuclear Information System (INIS)

    Udell, C.J.; Tilden, J.A.; Toyooka, R.T.

    1993-08-01

    The purpose of this paper is to provide a structured and cost-oriented process to determine risks associated with nuclear material and other security interests. Financial loss is a continuing concern for US Department of Energy contractors. In this paper risk is equated with uncertainty of cost impacts to material assets or human resources. The concept provides a method for assessing the effectiveness of an integrated protection system, which includes operations, safety, emergency preparedness, and safeguards and security. The concept is suitable for application to sabotage evaluations. The protection of assets is based on risk associated with cost impacts to assets and the potential for undesirable events. This will allow managers to establish protection priorities in terms of the cost and the potential for the event, given the current level of protection

  14. Prometheus unbound - challenges of risk evaluation, risk classification, and risk management

    Energy Technology Data Exchange (ETDEWEB)

    Klinke, A.; Renn, O.

    1999-11-01

    For dealing with risks in a rational fashion, it is necessary to characterize risks and use the parameters of characterization as tools for designing appropriate actions. This reports suggests a set of criteria that one can use in evaluating risks. These criteria include: - Damage potential, i.e. the amount of damage that the hazard can cause; - probability of occurrence, i.e. the likelihood that a specific damage will occur; - incertitude, i.e., the remaining uncertainties that are not covered by the assessment of probabilities (subdivided in statistical uncertainties, genuine uncertainty, and ignorance); - ubiquity which defines the geographic dispersion of potential damages (intragenerational justice); - persistency which defines the temporal extension of potential damages (intergenerational justice); - irreversibility which describes the impossible restoration of the situation to the state before the damage occurred (possible restoration are e.g. reforestation and cleaning of water); - delay effects which characterize the time of latency between the initial event and the actual impact of damage. The time of latency could be of physical, chemical or biological nature; and - potential of mobilization which is understood as violation of individual, social or cultural interests and values generating social conflicts and psychological reactions by affected people. (orig.)

  15. Designing and evaluating risk-based surveillance systems

    DEFF Research Database (Denmark)

    Willeberg, Preben; Nielsen, Liza Rosenbaum; Salman, Mo

    2012-01-01

    Risk-based surveillance systems reveal occurrence of disease or infection in a sample of population units, which are selected on the basis of risk factors for the condition under study. The purpose of such systems for supporting practical animal disease policy formulations and management decisions...... with prudent use of resources while maintaining acceptable system performance. High-risk category units are selected for testing by identification of the presence of specific high-risk factor(s), while disregarding other factors that might also influence the risk. On this basis we argue that the most...... applicable risk estimate for use in designing and evaluating a risk-based surveillance system would be a crude (unadjusted) relative risk, odds ratio or apparent prevalence. Risk estimates found in the published literature, however, are often the results of multivariable analyses implicitly adjusting...

  16. Risk assessment and risk evaluation

    International Nuclear Information System (INIS)

    Niehaus, F.

    1978-01-01

    With the help of results of investigations and model calculations the risk of nuclear energy in routine operation is shown. In this context it is pointed out that the excellent operation results of reactors all over the world have led to the acceptability of risks from local loads no longer being in question. The attention of radiation protection is therefore focused on the emissions of long-living isotopes which collect in the atmosphere. With LWRs the risk of accidents is so minimal that statistical data is, and never will be available. One has to therefore fall back upon the so-called fault tree analyses. On the subject of risk evalution the author referred to a poll in Austria. From the result of this investigation one might conclude that nuclear energy serves as a crystallization point for a discussion of varying concepts for future development. More attention should be paid to this aspect from both sides, in order to objectify the further expansion of this source of energy. (orig./HP) [de

  17. From risk analysis to risk control in land transport of dangerous materials. Contribution of quantitative evaluation

    International Nuclear Information System (INIS)

    Hubert, Ph.; Pages, P.

    1985-03-01

    The different approaches of risks and risk management system are described: statistics, potential risk, prevention, information and intervention. Quantitative evaluation is developed: data collection, purposes and methods. Two examples of application are given on risks associated to road transport of propane and of uranium hexafluoride. In conclusion level of risk and practical use of studies on risks are examined. 41 refs [fr

  18. Risk-based Regulatory Evaluation Program methodology

    International Nuclear Information System (INIS)

    DuCharme, A.R.; Sanders, G.A.; Carlson, D.D.; Asselin, S.V.

    1987-01-01

    The objectives of this DOE-supported Regulatory Evaluation Progrwam are to analyze and evaluate the safety importance and economic significance of existing regulatory guidance in order to assist in the improvement of the regulatory process for current generation and future design reactors. A risk-based cost-benefit methodology was developed to evaluate the safety benefit and cost of specific regulations or Standard Review Plan sections. Risk-based methods can be used in lieu of or in combination with deterministic methods in developing regulatory requirements and reaching regulatory decisions

  19. Risk-benefit evaluation for large technological systems

    International Nuclear Information System (INIS)

    Okrent, D.

    1979-01-01

    The related topics of risk-benefit analysis, risk analysis, and risk-acceptance criteria (How safe is safe enough) are of growing importance. An interdisciplinary study on various aspects of these topics, including applications to nuclear power, was recently completed at the University of California, Los Angeles (UCLA), with the support of the National Science Foundation. In addition to more than 30 topical reports and various open-literature publications, a final report (UCLA-ENG-7777) to the study, titled ''A Generalized Evaluation Approach to Risk--Benefit for Large Technological Systems and Its Application to Nuclear Power'', was issued in early 1978. This article briefly summarizes portions of the final report dealing with general aspects of risk-benefit methodology, societal knowledge and perception of risk, and risk-acceptance criteria

  20. Risk evaluation mitigation strategies: the evolution of risk management policy.

    Science.gov (United States)

    Hollingsworth, Kristen; Toscani, Michael

    2013-04-01

    The United States Food and Drug Administration (FDA) has the primary regulatory responsibility to ensure that medications are safe and effective both prior to drug approval and while the medication is being actively marketed by manufacturers. The responsibility for safe medications prior to marketing was signed into law in 1938 under the Federal Food, Drug, and Cosmetic Act; however, a significant risk management evolution has taken place since 1938. Additional federal rules, entitled the Food and Drug Administration Amendments Act, were established in 2007 and extended the government's oversight through the addition of a Risk Evaluation and Mitigation Strategy (REMS) for certain drugs. REMS is a mandated strategy to manage a known or potentially serious risk associated with a medication or biological product. Reasons for this extension of oversight were driven primarily by the FDA's movement to ensure that patients and providers are better informed of drug therapies and their specific benefits and risks prior to initiation. This article provides an historical perspective of the evolution of medication risk management policy and includes a review of REMS programs, an assessment of the positive and negative aspects of REMS, and provides suggestions for planning and measuring outcomes. In particular, this publication presents an overview of the evolution of the REMS program and its implications.

  1. D & D screening risk evaluation guidance

    Energy Technology Data Exchange (ETDEWEB)

    Robers, S.K.; Golden, K.M.; Wollert, D.A.

    1995-09-01

    The Screening Risk Evaluation (SRE) guidance document is a set of guidelines provided for the uniform implementation of SREs performed on decontamination and decommissioning (D&D) facilities. Although this method has been developed for D&D facilities, it can be used for transition (EM-60) facilities as well. The SRE guidance produces screening risk scores reflecting levels of risk through the use of risk ranking indices. Five types of possible risk are calculated from the SRE: current releases, worker exposures, future releases, physical hazards, and criticality. The Current Release Index (CRI) calculates the current risk to human health and the environment, exterior to the building, from ongoing or probable releases within a one-year time period. The Worker Exposure Index (WEI) calculates the current risk to workers, occupants and visitors inside contaminated D&D facilities due to contaminant exposure. The Future Release Index (FRI) calculates the hypothetical risk of future releases of contaminants, after one year, to human health and the environment. The Physical Hazards Index (PHI) calculates the risks to human health due to factors other than that of contaminants. Criticality is approached as a modifying factor to the entire SRE, due to the fact that criticality issues are strictly regulated under DOE. Screening risk results will be tabulated in matrix form, and Total Risk will be calculated (weighted equation) to produce a score on which to base early action recommendations. Other recommendations from the screening risk scores will be made based either on individual index scores or from reweighted Total Risk calculations. All recommendations based on the SRE will be made based on a combination of screening risk scores, decision drivers, and other considerations, as determined on a project-by-project basis.

  2. Risk evaluation of remedial alternatives for the Hanford Site

    International Nuclear Information System (INIS)

    Clark, S.W.; Lane, N.K.; Swenson, L.

    1994-01-01

    Risk assessment is one of the many tools used to evaluate and select remedial alternatives and evaluate the risk associated with selected remedial alternatives during and after implementation. The risk evaluation of remedial alternatives (RERA) is performed to ensure selected alternatives are protective of human health and the environment. Final remedy selection is promulgated in a record of decision (ROD) and risks of the selected alternatives are documented. Included in the ROD documentation are the risk-related analyses for long-term effectiveness, short-term effectiveness, and overall protection of human health and the environment including how a remedy will eliminate, reduce or control risks and whether exposure will be reduced to acceptable levels. A major goal of RERA in the process leading to a ROD is to provide decision-makers with specific risk information that may be needed to choose among alternatives. For the Hanford Site, there are many considerations that must be addressed from a risk perspective. These include the large size of the Hanford Site, the presence of both chemical and radionuclide contamination, one likelihood of many analogues sites, public and worker health and safety, and stakeholder concern with ecological impacts from site contamination and remedial actions. A RERA methodology has been promulgated to (1) identify the points in the process leading to a ROD where risk assessment input is either required or desirable and (2) provide guidance on how to evaluate risks associated with remedial alternatives under consideration. The methodology and evaluations parallel EPA guidance requiring consideration of short-term impacts and the overall protectiveness of remedial actions for evaluating potential human health and ecological risks during selection of remedial alternatives, implementation of remedial measures, and following completion of remedial action

  3. Consumer Evaluations of Food Risk Management Quality in Europe

    NARCIS (Netherlands)

    Kleef, van E.; Houghton, J.R.; Krystallis, A.; Pfenning, U.; Rowe, G.; Dijk, van H.; Lans, van der I.A.; Frewer, L.J.

    2007-01-01

    In developing and implementing appropriate food risk management strategies, it is important to understand how consumers evaluate the quality of food risk management practices. The aim of this study is to model the underlying psychological factors influencing consumer evaluations of food risk

  4. Risk evaluation of medical and industrial radiation devices

    International Nuclear Information System (INIS)

    Jones, E.D.; Cunningham, R.E.; Rathbun, P.A.

    1994-03-01

    In 1991, the NRC, Division of Industrial and Medical Nuclear Safety, began a program to evaluate the use of probabilistic risk assessment (PRA) in regulating medical devices. This program represents an initial step in an overall plant to evaluate the use of PRA in regulating the use of nuclear by-product materials. The NRC envisioned that the use of risk analysis techniques could assist staff in ensuring that the regulatory approach was standardized, understandable, and effective. Traditional methods of assessing risk in nuclear power plants may be inappropriate to use in assessing the use of by-product devices. The approaches used in assessing nuclear reactor risks are equipment-oriented. Secondary attention is paid to the human component, for the most part after critical system failure events have been identified. This paper describes the risk methodology developed by Lawrence Livermore National Laboratory (LLNL), initially intended to assess risks associated with the use of the Gamma Knife, a gamma stereotactic radiosurgical device. For relatively new medical devices such as the Gamma Knife, the challenge is to perform a risk analysis with very little quantitative data but with an important human factor component. The method described below provides a basic approach for identifying the most likely risk contributors and evaluating their relative importance. The risk analysis approach developed for the Gamma Knife and described in this paper should be applicable to a broader class of devices in which the human interaction with the device is a prominent factor. In this sense, the method could be a prototypical model of nuclear medical or industrial device risk analysis

  5. Evaluating risk management strategies in resource planning

    International Nuclear Information System (INIS)

    Andrews, C.J.

    1995-01-01

    This paper discusses the evaluation of risk management strategies as a part of integrated resource planning. Value- and scope-related uncertainties can be addressed during the process of planning, but uncertainties in the operating environment require technical analysis within planning models. Flexibility and robustness are two key classes of strategies for managing the risk posed by these uncertainties. This paper reviews standard capacity expansion planning models and shows that they are poorly equipped to compare risk management strategies. Those that acknowledge uncertainty are better at evaluating robustness than flexibility, which implies a bias against flexible options. Techniques are available to overcome this bias

  6. Hierarchic Analysis Method to Evaluate Rock Burst Risk

    Directory of Open Access Journals (Sweden)

    Ming Ji

    2015-01-01

    Full Text Available In order to reasonably evaluate the risk of rock bursts in mines, the factors impacting rock bursts and the existing grading criterion on the risk of rock bursts were studied. By building a model of hierarchic analysis method, the natural factors, technology factors, and management factors that influence rock bursts were analyzed and researched, which determined the degree of each factor’s influence (i.e., weight and comprehensive index. Then the grade of rock burst risk was assessed. The results showed that the assessment level generated by the model accurately reflected the actual risk degree of rock bursts in mines. The model improved the maneuverability and practicability of existing evaluation criteria and also enhanced the accuracy and science of rock burst risk assessment.

  7. Risk evaluation system for facility safeguards and security planning

    International Nuclear Information System (INIS)

    Udell, C.J.; Carlson, R.L.

    1987-01-01

    The Risk Evaluation System (RES) is an integrated approach to determining safeguards and security effectiveness and risk. RES combines the planning and technical analysis into a format that promotes an orderly development of protection strategies, planing assumptions, facility targets, vulnerability and risk determination, enhancement planning, and implementation. In addition, the RES computer database program enhances the capability of the analyst to perform a risk evaluation of the facility. The computer database is menu driven using data input screens and contains an algorithm for determining the probability of adversary defeat and risk. Also, base case and adjusted risk data records can be maintained and accessed easily

  8. Risk evaluation system for facility safeguards and security planning

    International Nuclear Information System (INIS)

    Udell, C.J.; Carlson, R.L.

    1987-01-01

    The Risk Evaluation System (RES) is an integrated approach to determining safeguards and security effectiveness and risk. RES combines the planning and technical analysis into a format that promotes an orderly development of protection strategies, planning assumptions, facility targets, vulnerability and risk determination, enhancement planning, and implementation. In addition, the RES computer database program enhances the capability of the analyst to perform a risk evaluation of the facility. The computer database is menu driven using data input screens and contains an algorithm for determining the probability of adversary defeat and risk. Also, base case and adjusted risk data records can be maintained and accessed easily

  9. At-Risk Youth Appearance and Job Performance Evaluation

    Science.gov (United States)

    Freeburg, Beth Winfrey; Workman, Jane E.

    2008-01-01

    The goal of this study was to identify the relationship of at-risk youth workplace appearance to other job performance criteria. Employers (n = 30; each employing from 1 to 17 youths) evaluated 178 at-risk high school youths who completed a paid summer employment experience. Appearance evaluations were significantly correlated with evaluations of…

  10. Risk identification and evaluation of customer collaboration in product development

    Directory of Open Access Journals (Sweden)

    Xuefeng Zhang

    2015-05-01

    Full Text Available Purpose: The purpose of this paper is to identify risk factors that caused by customer collaboration in new product development systematically, and propose an approach to judge which risk factors are critical and catch substantial attention. Design/methodology/approach: This study identifies risk factors according to the results of case studies of enterprises in china. On this basis, an improved rough number approach is put forward to evaluate the importance of risk factors. Findings: Firstly, classify risk factors into three aspects. Then, present a risk factor set, which include thirty-seven risk factors. At last, determine which risk factors are critical by using an improved rough number approach. Originality/value: Considering there are few researches studying comprehensive risk factors of customer collaboration and assessing them, this paper explores a risk factor set of customer collaboration in product development stage, and proposes a novel approach, which can help to solve the problem of subjective, vague and lack of prior information of evaluation, to evaluate risk factors.

  11. RISK ANALYSIS AND EVALUATION FOR CRITICAL LOGISTICAL INFRASTRUCTURE

    Directory of Open Access Journals (Sweden)

    Sascha Düerkop

    2016-12-01

    Full Text Available Logistical infrastructure builds the backbone of an economy. Without an effective logistical infrastructure in place, the supply for both enterprises and consumers might not be met. But even a high-quality logistical infrastructure can be threatened by risks. Thus, it is important to identify, analyse, and evaluate risks for logistical infrastructure that might threaten logistical processes. Only if those risks are known and their impact estimated, decision makers can implement counteractive measures to reduce risks. In this article, we develop a network-based approach that allows for the evaluation of risks and their consequences onto the logistical network. We will demonstrate the relevance of this approach by applying it to the logistics network of the central German state of Hesse. Even though transport data is extensively tracked and recorded nowadays, typical daily risks, like accidents on a motorway, and extraordinary risks, like a bridge at risk to collapse, terrorist attacks or climate-related catastrophes, are not systematically anticipated. Several studies unveiled recently that the overall impact for an economy of possible failures of single nodes and/or edges in a network are not calculated, and particularly critical edges are not identified in advance. We address this information gap by a method that helps to identify and quantify risks in a given network. To reach this objective, we define a mathematical optimization model that quantifies the current “risk-related costs” of the overall network and quantify the risk by investigating the change of the overall costs in the case a risk is realized.

  12. A risk evaluation model and its application in online retailing trustfulness

    Science.gov (United States)

    Ye, Ruyi; Xu, Yingcheng

    2017-08-01

    Building a general model for risks evaluation in advance could improve the convenience, normality and comparability of the results of repeating risks evaluation in the case that the repeating risks evaluating are in the same area and for a similar purpose. One of the most convenient and common risks evaluation models is an index system including of several index, according weights and crediting method. One method to build a risk evaluation index system that guarantees the proportional relationship between the resulting credit and the expected risk loss is proposed and an application example is provided in online retailing in this article.

  13. Risk variables in evaluation of transport projects

    Science.gov (United States)

    Vařbuchta, Petr; Kovářová, Hana; Hromádka, Vít; Vítková, Eva

    2017-09-01

    Depending on the constantly increasing demands on assessment of investment projects, especially assessment of large-scale projects in transport and important European projects with wide impacts, there is constantly increasing focus on risk management, whether to find mitigations, creating corrective measures or their implementation in assessment, especially in the context of Cost-Benefit analysis. To project assessment is often used implementation of certain risk variables, which can generate negative impacts of project outputs in framework of assess. Especially in case of transportation infrastructure projects is taken much emphasis on the influence of risk variables. However, currently in case of assessment of transportation projects is in Czech Republic used a few risk variables, which occur in the most projects. This leads to certain limitation in framework of impact assessment of risk variables. This papers aims to specify a new risk variables and process of applying them to already executed project assessment. Based on changes generated by new risk variables will be evaluated differences between original and adapted assessment.

  14. Risk evaluation system for operational events and inspection findings

    International Nuclear Information System (INIS)

    Lopez G, A.; Godinez S, V.; Lopez M, R.

    2010-10-01

    The Mexican Nuclear Regulatory Commission has developed an adaptation of the US NRC Significance Determination Process (SDP) to evaluate the risk significance of operational events and inspection findings in Laguna Verde nuclear power plant. The Mexican Nuclear Regulatory Commission developed a plant specific flow chart for preliminary screening instead of the open questionnaire used by the US NRC-SDP, with the aim to improve the accuracy of the screening process. Also, the work sheets and support information tables required by the SDP were built up in an Excel application which allows to perform the risk evaluation in an automatic way, focusing the regulator staff efforts in the risk significance analysis instead of the risk calculation tasks. In order to construct this tool a simplified PRA model was developed and validated with the individual plant examination model. This paper shows the Mexican Nuclear Regulatory Commission process and some risk events evaluations performed using the Risk Evaluation System for Operational Events and Inspection Findings (SERHE, by its acronyms in Spanish). (Author)

  15. Proposal of a risk-factor-based analytical approach for integrating occupational health and safety into project risk evaluation.

    Science.gov (United States)

    Badri, Adel; Nadeau, Sylvie; Gbodossou, André

    2012-09-01

    Excluding occupational health and safety (OHS) from project management is no longer acceptable. Numerous industrial accidents have exposed the ineffectiveness of conventional risk evaluation methods as well as negligence of risk factors having major impact on the health and safety of workers and nearby residents. Lack of reliable and complete evaluations from the beginning of a project generates bad decisions that could end up threatening the very existence of an organization. This article supports a systematic approach to the evaluation of OHS risks and proposes a new procedure based on the number of risk factors identified and their relative significance. A new concept called risk factor concentration along with weighting of risk factor categories as contributors to undesirable events are used in the analytical hierarchy process multi-criteria comparison model with Expert Choice(©) software. A case study is used to illustrate the various steps of the risk evaluation approach and the quick and simple integration of OHS at an early stage of a project. The approach allows continual reassessment of criteria over the course of the project or when new data are acquired. It was thus possible to differentiate the OHS risks from the risk of drop in quality in the case of the factory expansion project. Copyright © 2011 Elsevier Ltd. All rights reserved.

  16. Credit Risk Evaluation of Power Market Players with Random Forest

    Science.gov (United States)

    Umezawa, Yasushi; Mori, Hiroyuki

    A new method is proposed for credit risk evaluation in a power market. The credit risk evaluation is to measure the bankruptcy risk of the company. The power system liberalization results in new environment that puts emphasis on the profit maximization and the risk minimization. There is a high probability that the electricity transaction causes a risk between companies. So, power market players are concerned with the risk minimization. As a management strategy, a risk index is requested to evaluate the worth of the business partner. This paper proposes a new method for evaluating the credit risk with Random Forest (RF) that makes ensemble learning for the decision tree. RF is one of efficient data mining technique in clustering data and extracting relationship between input and output data. In addition, the method of generating pseudo-measurements is proposed to improve the performance of RF. The proposed method is successfully applied to real financial data of energy utilities in the power market. A comparison is made between the proposed and the conventional methods.

  17. Risk management study for the retired Hanford Site facilities: Qualitative risk evaluation for the retired Hanford Site facilities

    International Nuclear Information System (INIS)

    Coles, G.A.; Shultz, M.V.; Taylor, W.E.

    1993-09-01

    This document provides a risk evaluation of the 100 and 200 Area retired, surplus facilities on the Hanford Site. Also included are the related data that were compiled by the risk evaluation team during investigations performed on the facilities. Results are the product of a major effort performed in fiscal year 1993 to produce qualitative information that characterizes certain risks associated with these facilities. The retired facilities investigated for this evaluation are located in the 100 and 200 Areas of the 1,450-km 2 (570-mi 2 ) Hanford Site. The Hanford Site is a semiarid tract of land in southeastern Washington State. The nearest population center is Richland, Washington, (population 32,000) 30-km (20 mi) southeast of the 200 Area. During walkdown investigations of these facilities, data on real and potential hazards that threatened human health or safety or created potential environmental release issues were identified by the risk evaluation team. Using these findings, the team categorized the identified hazards by facility and evaluated the risk associated with each hazard. The factors contributing to each risk, and the consequence and likelihood of harm associated with each hazard also are included in this evaluation

  18. [Guidance of FDA risk evaluation and mitigation strategy and enlightenment to drug risk management of post-marketing Chinese medicine].

    Science.gov (United States)

    Li, Yuanyuan; Xie, Yanming

    2011-10-01

    The FDA risk evaluation and mitigation strategy (REMS) aims to drugs or biological products known or potential serious risk management. Analysis with the example of the content of the Onsolis REMS named FOCOS. Our country can be reference for the analysis of relevant experience and establish a scientific evaluation mechanism, strengthen the drug risk consciousness, promote the rational drug use, organic combined with the before-marketing and post-marketing evaluation of traditional Chinese medicine, and promote the evaluation of risk management of the drug development and improvement.

  19. Evaluation of allowed outage times (AOTS) from a risk and reliability standpoint

    International Nuclear Information System (INIS)

    Vesely, W.E.

    1989-08-01

    This report describes the basic risks associated with allowed outage times (AOTS), defines strategies for selecting the risks to be quantified, and describes how the risks can be quantified. This report provides a basis for risk-based approaches for regulatory and plant implementation. The AOT risk evaluations can be applied to proposed one-time AOT changes, or to permanent changes. The evaluations can also be used to quantify risks associated with present AOTs, and in establishing AOTs from a risk perspective. The report shows that the standard way of calculating AOT risks in probabilistic risk analyses (PRAs) generally is not sufficient when evaluating all the risks associated with an AOT in order to assess its acceptability. The PRA calculates an average AOT risk which includes the frequency at which the AOT is expected to occur. Other risks associated with an AOT include the single downtime risk, which is the risk incurred when (given) the AOT has occurred. The single downtime risk is generally the most applicable risk in determining the acceptability of the AOT. The single downtime risks are generally much larger than the PRA-averaged risk. For more comprehensive evaluations, both risks should be calculated. The report also describes other risks which can be considered, including personnel and economic risks. Finally, the report discusses the detailed evaluations which are involved in calculating AOT risks, including considerations of uncertainty. (author)

  20. Evaluation of test intervals strategies with a risk monitor

    International Nuclear Information System (INIS)

    Soerman, J.

    2005-01-01

    The Swedish nuclear power utility Oskarshamn Power Group (OKG), is investigating how the use of a risk monitor can facilitate and improve risk-informed decision-making at their nuclear power plants. The intent is to evaluate if risk-informed decision-making can be accepted. A pilot project was initiated and carried out in 2004. The project included investigating if a risk monitor can be used for optimising test intervals for diesel- and gas turbine generators with regard to risk level. The Oskarhamn 2 (O2), PSA Level 1 model was converted into a risk monitor using RiskSpectrum RiskWatcher (RSRW) software. The converted PSA model included the complete PSA model for the power operation mode. RSRW then performs a complete requantification for every analysis. Time dependent reliability data are taken into account, i.e. a shorter test interval will increases the components availability (possibility to e.g. start on demand). The converted O2 model was then used to investigate whether it would be possible to balance longer test intervals for diesel generators, gas turbine generators and high pressure injection system with shorter test intervals for the low pressure injection system, while maintaining a low risk level at the plant. The results show that a new mixture of test intervals can be implemented with only marginally changes in the risk calculated with the risk monitor model. The results indicate that the total number of test activities for the systems included in the pilot study could be reduced by 20% with a maintained level of risk. A risk monitor taking into account the impact from test intervals in availability calculations for components is well suited for evaluation of test interval strategies. It also enables the analyst to evaluate the risk level over a period of time including the impact the actual status of the plant may have on the risk level. (author)

  1. Evaluating emergency risk communications: a dialogue with the experts.

    Science.gov (United States)

    Thomas, Craig W; Vanderford, Marsha L; Crouse Quinn, Sandra

    2008-10-01

    Evaluating emergency risk communications is fraught with challenges since communication can be approached from both a systemic and programmatic level. Therefore, one must consider stakeholders' perspectives, effectiveness issues, standards of evidence and utility, and channels of influence (e.g., mass media and law enforcement). Evaluation issues related to timing, evaluation questions, methods, measures, and accountability are raised in this dialogue with emergency risk communication specialists. Besides the usual evaluation competencies, evaluators in this area need to understand and work collaboratively with stakeholders and be attuned to the dynamic contextual nature of emergency risk communications. Sample resources and measures are provided here to aid in this emerging and exciting field of evaluation.

  2. Evaluating the risks of clinical research: direct comparative analysis.

    Science.gov (United States)

    Rid, Annette; Abdoler, Emily; Roberson-Nay, Roxann; Pine, Daniel S; Wendler, David

    2014-09-01

    Many guidelines and regulations allow children and adolescents to be enrolled in research without the prospect of clinical benefit when it poses minimal risk. However, few systematic methods exist to determine when research risks are minimal. This situation has led to significant variation in minimal risk judgments, raising concern that some children are not being adequately protected. To address this concern, we describe a new method for implementing the widely endorsed "risks of daily life" standard for minimal risk. This standard defines research risks as minimal when they do not exceed the risks posed by daily life activities or routine examinations. This study employed a conceptual and normative analysis, and use of an illustrative example. Different risks are composed of the same basic elements: Type, likelihood, and magnitude of harm. Hence, one can compare the risks of research and the risks of daily life by comparing the respective basic elements with each other. We use this insight to develop a systematic method, direct comparative analysis, for implementing the "risks of daily life" standard for minimal risk. The method offers a way of evaluating research procedures that pose the same types of risk as daily life activities, such as the risk of experiencing anxiety, stress, or other psychological harm. We thus illustrate how direct comparative analysis can be applied in practice by using it to evaluate whether the anxiety induced by a respiratory CO2 challenge poses minimal or greater than minimal risks in children and adolescents. Direct comparative analysis is a systematic method for applying the "risks of daily life" standard for minimal risk to research procedures that pose the same types of risk as daily life activities. It thereby offers a method to protect children and adolescents in research, while ensuring that important studies are not blocked because of unwarranted concerns about research risks.

  3. Gasbuggy Site Assessment and Risk Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-03-01

    This report describes the geologic and hydrologic conditions and evaluates potential health risks to workers in the natural gas industry in the vicinity of the Gasbuggy, New Mexico, site, where the U.S. Atomic Energy Commission detonated an underground nuclear device in 1967. The 29-kiloton detonation took place 4,240 feet below ground surface and was designed to evaluate the use of a nuclear detonation to enhance natural gas production from the Pictured Cliffs Formation in the San Juan Basin, Rio Arriba County, New Mexico, on land administered by Carson National Forest. A site-specific conceptual model was developed based on current understanding of the hydrologic and geologic environment. This conceptual model was used for establishing plausible contaminant exposure scenarios, which were then evaluated for human health risk potential. The most mobile and, therefore, the most probable contaminant that could result in human exposure is tritium. Natural gas production wells were identified as having the greatest potential for bringing detonation-derived contaminants (tritium) to the ground surface in the form of tritiated produced water. Three exposure scenarios addressing potential contamination from gas wells were considered in the risk evaluation: a gas well worker during gas-well-drilling operations, a gas well worker performing routine maintenance, and a residential exposure. The residential exposure scenario was evaluated only for comparison; permanent residences on national forest lands at the Gasbuggy site are prohibited

  4. D ampersand D screening risk evaluation guidance

    International Nuclear Information System (INIS)

    Robers, S.K.; Golden, K.M.; Wollert, D.A.

    1995-09-01

    The Screening Risk Evaluation (SRE) guidance document is a set of guidelines provided for the uniform implementation of SREs performed on decontamination and decommissioning (D ampersand D) facilities. Although this method has been developed for D ampersand D facilities, it can be used for transition (EM-60) facilities as well. The SRE guidance produces screening risk scores reflecting levels of risk through the use of risk ranking indices. Five types of possible risk are calculated from the SRE: current releases, worker exposures, future releases, physical hazards, and criticality. The Current Release Index (CRI) calculates the current risk to human health and the environment, exterior to the building, from ongoing or probable releases within a one-year time period. The Worker Exposure Index (WEI) calculates the current risk to workers, occupants and visitors inside contaminated D ampersand D facilities due to contaminant exposure. The Future Release Index (FRI) calculates the hypothetical risk of future releases of contaminants, after one year, to human health and the environment. The Physical Hazards Index (PHI) calculates the risks to human health due to factors other than that of contaminants. Criticality is approached as a modifying factor to the entire SRE, due to the fact that criticality issues are strictly regulated under DOE. Screening risk results will be tabulated in matrix form, and Total Risk will be calculated (weighted equation) to produce a score on which to base early action recommendations. Other recommendations from the screening risk scores will be made based either on individual index scores or from reweighted Total Risk calculations. All recommendations based on the SRE will be made based on a combination of screening risk scores, decision drivers, and other considerations, as determined on a project-by-project basis

  5. Evaluating investments in renewable energy under policy risks

    International Nuclear Information System (INIS)

    Gatzert, Nadine; Vogl, Nikolai

    2016-01-01

    The considerable amount of required infrastructure and renewable energy investments expected in the forthcoming years also implies an increasingly relevant contribution of private and institutional investors. In this context, especially regulatory and policy risks have been shown to play a major role for investors when evaluating investments in renewable energy and should thus also be taken into account in risk assessment and when deriving risk-return profiles. In this paper, we provide a stochastic model framework to quantify policy risks associated with renewable energy investments (e.g. a retrospective reduction of a feed-in tariff), thereby also taking into account energy price risk, resource risk, and inflation risk. The model is illustrated by means of simulations and scenario analyses, and it makes use of expert estimates and fuzzy set theory for quantifying policy risks. Our numerical results for a portfolio of onshore wind farms in Germany and France show that policy risk can strongly impact risk-return profiles, and that cross-country diversification effects can considerably decrease the overall risk for investors. - Highlights: •Quantification of policy risks associated with renewable energy investments. •Results emphasize that policy risk has a major impact on risk and return. •Study of the cross-country diversification potential. •Cross-country diversification can considerably decrease the risk for an investor.

  6. Occupational health and safety: Designing and building with MACBETH a value risk-matrix for evaluating health and safety risks

    Science.gov (United States)

    Lopes, D. F.; Oliveira, M. D.; Costa, C. A. Bana e.

    2015-05-01

    Risk matrices (RMs) are commonly used to evaluate health and safety risks. Nonetheless, they violate some theoretical principles that compromise their feasibility and use. This study describes how multiple criteria decision analysis methods have been used to improve the design and the deployment of RMs to evaluate health and safety risks at the Occupational Health and Safety Unit (OHSU) of the Regional Health Administration of Lisbon and Tagus Valley. ‘Value risk-matrices’ (VRMs) are built with the MACBETH approach in four modelling steps: a) structuring risk impacts, involving the construction of descriptors of impact that link risk events with health impacts and are informed by scientific evidence; b) generating a value measurement scale of risk impacts, by applying the MACBETH-Choquet procedure; c) building a system for eliciting subjective probabilities that makes use of a numerical probability scale that was constructed with MACBETH qualitative judgments on likelihood; d) and defining a classification colouring scheme for the VRM. A VRM built with OHSU members was implemented in a decision support system which will be used by OHSU members to evaluate health and safety risks and to identify risk mitigation actions.

  7. Sustainability Risk Evaluation for Large-Scale Hydropower Projects with Hybrid Uncertainty

    Directory of Open Access Journals (Sweden)

    Weiyao Tang

    2018-01-01

    Full Text Available As large-scale hydropower projects are influenced by many factors, risk evaluations are complex. This paper considers a hydropower project as a complex system from the perspective of sustainability risk, and divides it into three subsystems: the natural environment subsystem, the eco-environment subsystem and the socioeconomic subsystem. Risk-related factors and quantitative dimensions of each subsystem are comprehensively analyzed considering uncertainty of some quantitative dimensions solved by hybrid uncertainty methods, including fuzzy (e.g., the national health degree, the national happiness degree, the protection of cultural heritage, random (e.g., underground water levels, river width, and fuzzy random uncertainty (e.g., runoff volumes, precipitation. By calculating the sustainability risk-related degree in each of the risk-related factors, a sustainable risk-evaluation model is built. Based on the calculation results, the critical sustainability risk-related factors are identified and targeted to reduce the losses caused by sustainability risk factors of the hydropower project. A case study at the under-construction Baihetan hydropower station is presented to demonstrate the viability of the risk-evaluation model and to provide a reference for the sustainable risk evaluation of other large-scale hydropower projects.

  8. AN EVALUATION OF RISK MANAGEMENT STRATEGIES FOR DAIRY FARMS

    OpenAIRE

    Bosch, Darrell J.; Johnson, Christian J.

    1992-01-01

    Variability in feed prices and crop yields are important sources of risk to dairy farmers. A simulation model of a representative dairy farm was used to evaluate crop insurance and hedging as risk management strategies. These strategies lowered expected net returns but also reduced risk. The preferred set of strategies at lower levels of risk aversion included hedging and crop insurance, although a base scenario in which no risk management strategies were employed was also efficient. The pref...

  9. Assessment of three risk evaluation systems for patients aged ≥70 in East China: performance of SinoSCORE, EuroSCORE II and the STS risk evaluation system.

    Science.gov (United States)

    Shan, Lingtong; Ge, Wen; Pu, Yiwei; Cheng, Hong; Cang, Zhengqiang; Zhang, Xing; Li, Qifan; Xu, Anyang; Wang, Qi; Gu, Chang; Zhang, Yangyang

    2018-01-01

    To assess and compare the predictive ability of three risk evaluation systems (SinoSCORE, EuroSCORE II and the STS risk evaluation system) in patients aged ≥70, and who underwent coronary artery bypass grafting (CABG) in East China. Three risk evaluation systems were applied to 1,946 consecutive patients who underwent isolated CABG from January 2004 to September 2016 in two hospitals. Patients were divided into two subsets according to their age: elderly group (age ≥70) with a younger group (age evaluation system were 0.78(0.64)%, 1.43(1.14)% and 0.78(0.77)%, respectively. SinoSCORE achieved the best discrimination (the area under the receiver operating characteristic curve (AUC) = 0.829), followed by the STS risk evaluation system (AUC = 0.790) and EuroSCORE II (AUC = 0.769) in the entire cohort. In the elderly group, the observed mortality rate was 4.82% while it was 1.38% in the younger group. SinoSCORE (AUC = .829) also achieved the best discrimination in the elderly group, followed by the STS risk evaluation system (AUC = .730) and EuroSCORE II (AUC = 0.640) while all three risk evaluation systems all had good performances in the younger group. SinoSCORE, EuroSCORE II and the STS risk evaluation system all achieved positive calibrations in the entire cohort and subsets. The performance of the three risk evaluation systems was not ideal in the entire cohort. In the elderly group, SinoSCORE appeared to achieve better predictive efficiency than EuroSCORE II and the STS risk evaluation system.

  10. Evaluation of a constipation risk assessment scale.

    Science.gov (United States)

    Zernike, W; Henderson, A

    1999-06-01

    This project was undertaken in order to evaluate the utility of a constipation risk assessment scale and the accompanying bowel management protocol. The risk assessment scale was primarily introduced to teach and guide staff in managing constipation when caring for patients. The intention of the project was to reduce the incidence of constipation in patients during their admission to hospital.

  11. A Scalable Distribution Network Risk Evaluation Framework via Symbolic Dynamics

    Science.gov (United States)

    Yuan, Kai; Liu, Jian; Liu, Kaipei; Tan, Tianyuan

    2015-01-01

    Background Evaluations of electric power distribution network risks must address the problems of incomplete information and changing dynamics. A risk evaluation framework should be adaptable to a specific situation and an evolving understanding of risk. Methods This study investigates the use of symbolic dynamics to abstract raw data. After introducing symbolic dynamics operators, Kolmogorov-Sinai entropy and Kullback-Leibler relative entropy are used to quantitatively evaluate relationships between risk sub-factors and main factors. For layered risk indicators, where the factors are categorized into four main factors – device, structure, load and special operation – a merging algorithm using operators to calculate the risk factors is discussed. Finally, an example from the Sanya Power Company is given to demonstrate the feasibility of the proposed method. Conclusion Distribution networks are exposed and can be affected by many things. The topology and the operating mode of a distribution network are dynamic, so the faults and their consequences are probabilistic. PMID:25789859

  12. Evaluation on lifetime risk in reinforced concrete structure; RC kozo no lifetime risk no hyoka ni kansuru kisoteki kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, M. [Public Works Research Institute, Tsukuba (Japan); Adachi, H. [Taisei Corp., Tokyo (Japan); Akakura, Y. [Ministry of Transport, Tokyo (Japan); Ibayashi, K.; Ozaka, Y. [Tohoku Gakuin Univ., Sendai (Japan)

    1996-02-15

    To evaluate the risk during longevity of reinforced concrete structure subjected to earthquake motions, called lifetime risk, damage and safety were estimated by means of the earthquake risk analysis and earthquake response analysis. For the earthquake risk analysis, historical earthquake data with relatively low accuracy were efficiently taken into account, to determine the annual mean generation probability against the earthquake motion strength in ten main cities. A new damage index with load hysteresis was defined as an anti-earthquake evaluation index where accumulative damage is taken into consideration. Assuming that the damage transits from `certain state` to `certain state` every time the earthquake motion generates at the noticeable place, damage transition matrix expressing transition probability was calculated by using the results of earthquake risk analysis and the accumulative damage index. The lifetime risk was calculated from the damage transition matrix and the earthquake motion generation probability, to evaluate the safety. 21 refs., 10 figs., 8 tabs.

  13. Evaluation of AECB-1119, risk of energy production

    International Nuclear Information System (INIS)

    1978-01-01

    The Inhaber report, 'Risk of Energy Production', is evaluated based on how the conclusions of the report match its objectives, the methodology used to reach the report's conclusions, and the presentation of the report. The authors recommend that a second volume containing the pertinent data used in the report should be published; and that total risks should be calculated ignoring material acquisition, construction and transportation risks, using the actual energy output of the various systems without imposing a backup energy supply, and comparing systems in such a way that death, injury and disease risks may be considered separately. They propose that the Atomic Energy Control Board should show how the report results relate to nuclear safety, and that the AECB should clarify the criteria for evaluating the small probability of a catastrophic nuclear accident. The response of the author of AECB--1119 is given in a separate section

  14. The determination of allowed outage time using the evaluation of transition risk

    International Nuclear Information System (INIS)

    Kang, D. I.; Kim, K. Y.; Jang, S. C.

    2001-03-01

    he objectives of this study are to propose a new evaluation method for transition risk and to determine the AOT using the new method. We review and compare the evaluation methods of transition risk which was previously studied. We also identify important assumptions used in previous studies for the evaluation of transition risk. We select general items required for the development of evaluation method for the transition risk. Based on the items selected, we propose a new evaluation method for transition risk. The new evaluation method for the transition risk is based on following assumptions; 1)For the same time span, the risk occurred from the failure to the completion of component repair during power operation is the same as the total risk including the risk occurred from power operation to specific shutdown/low power operation and the risk from specific shutdown/low power operation to power operation. 2)Shutdown operation and the repair of components are initiated just after the identification of the failure of components. The evaluation of the transition risk is performed to incorporate the characteristics of shutdown operation into Ulchin Units 3 and 4 Level 1 internal PSA for power operation. The application results of the new method to the HPSIS and the LPSIS for Ulchin Units 3 and 4 show that the AOT of HPSIS is properly determined and the AOT of LPSIS can be greatly increased. In this study, the main factors affecting the determination of AOT using the evaluation for transition risk are identified as the time of shutdown operation, the consideration of the change on common cause failure probability, and the risk of shutdown operation. It is expected that the evaluation method for the transition risk proposed in this study will be used for the determination of AOT and for the decision, in the case of the components unavailable, whether power operation is continuously performed or shutdown operation is initiated

  15. Risk assessment and remedial policy evaluation using predictive modeling

    International Nuclear Information System (INIS)

    Linkov, L.; Schell, W.R.

    1996-01-01

    As a result of nuclear industry operation and accidents, large areas of natural ecosystems have been contaminated by radionuclides and toxic metals. Extensive societal pressure has been exerted to decrease the radiation dose to the population and to the environment. Thus, in making abatement and remediation policy decisions, not only economic costs but also human and environmental risk assessments are desired. This paper introduces a general framework for risk assessment and remedial policy evaluation using predictive modeling. Ecological risk assessment requires evaluation of the radionuclide distribution in ecosystems. The FORESTPATH model is used for predicting the radionuclide fate in forest compartments after deposition as well as for evaluating the efficiency of remedial policies. Time of intervention and radionuclide deposition profile was predicted as being crucial for the remediation efficiency. Risk assessment conducted for a critical group of forest users in Belarus shows that consumption of forest products (berries and mushrooms) leads to about 0.004% risk of a fatal cancer annually. Cost-benefit analysis for forest cleanup suggests that complete removal of organic layer is too expensive for application in Belarus and a better methodology is required. In conclusion, FORESTPATH modeling framework could have wide applications in environmental remediation of radionuclides and toxic metals as well as in dose reconstruction and, risk-assessment

  16. Risk evaluation and monitoring in multiple sclerosis therapeutics.

    Science.gov (United States)

    Clanet, Michel C; Wolinsky, Jerry S; Ashton, Raymond J; Hartung, Hans-Peter; Reingold, Stephen C

    2014-09-01

    Risk for multiple sclerosis (MS) disease-modifying therapies (DMT) must be assessed on an ongoing basis. Early concerns regarding the first-approved DMTs for MS have been mitigated, but recently licensed therapies have been linked to possibly greater risks. The objective of this review is to discuss risk assessment in MS therapeutics based on an international workshop and comprehensive literature search and recommend strategies for risk assessment/monitoring. Assessment and perception of therapeutic risks vary between patients, doctors and regulators. Acceptability of risk depends on the magnitude of risk and the demonstrated clinical benefits of any agent. Safety signals must be distinguishable from chance occurrences in a clinical trial and in long-term use of medications. Post-marketing research is crucial for assessing longer-term safety in large patient cohorts. Reporting of adverse events is becoming more proactive, allowing more rapid identification of risks. Communication about therapeutic risks and their relationship to clinical benefit must involve patients in shared decision making. It is difficult to produce a general risk-assessment algorithm for all MS therapies. Specific algorithms are required for each DMT in every treated-patient population. New and evolving risks must be evaluated and communicated rapidly to allow patients and physicians to be well informed and able to share treatment decisions. © The Author(s) 2013.

  17. Risk management study for the retired Hanford Site facilities: Qualitative risk evaluation for the retired Hanford Site facilities. Volume 3

    Energy Technology Data Exchange (ETDEWEB)

    Coles, G.A.; Shultz, M.V.; Taylor, W.E.

    1993-09-01

    This document provides a risk evaluation of the 100 and 200 Area retired, surplus facilities on the Hanford Site. Also included are the related data that were compiled by the risk evaluation team during investigations performed on the facilities. Results are the product of a major effort performed in fiscal year 1993 to produce qualitative information that characterizes certain risks associated with these facilities. The retired facilities investigated for this evaluation are located in the 100 and 200 Areas of the 1,450-km{sup 2} (570-mi{sup 2}) Hanford Site. The Hanford Site is a semiarid tract of land in southeastern Washington State. The nearest population center is Richland, Washington, (population 32,000) 30-km (20 mi) southeast of the 200 Area. During walkdown investigations of these facilities, data on real and potential hazards that threatened human health or safety or created potential environmental release issues were identified by the risk evaluation team. Using these findings, the team categorized the identified hazards by facility and evaluated the risk associated with each hazard. The factors contributing to each risk, and the consequence and likelihood of harm associated with each hazard also are included in this evaluation.

  18. Conceptual Model of Offshore Wind Environmental Risk Evaluation System

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Richard M.; Copping, Andrea E.; Van Cleve, Frances B.; Unwin, Stephen D.; Hamilton, Erin L.

    2010-06-01

    In this report we describe the development of the Environmental Risk Evaluation System (ERES), a risk-informed analytical process for estimating the environmental risks associated with the construction and operation of offshore wind energy generation projects. The development of ERES for offshore wind is closely allied to a concurrent process undertaken to examine environmental effects of marine and hydrokinetic (MHK) energy generation, although specific risk-relevant attributes will differ between the MHK and offshore wind domains. During FY10, a conceptual design of ERES for offshore wind will be developed. The offshore wind ERES mockup described in this report will provide a preview of the functionality of a fully developed risk evaluation system that will use risk assessment techniques to determine priority stressors on aquatic organisms and environments from specific technology aspects, identify key uncertainties underlying high-risk issues, compile a wide-range of data types in an innovative and flexible data organizing scheme, and inform planning and decision processes with a transparent and technically robust decision-support tool. A fully functional version of ERES for offshore wind will be developed in a subsequent phase of the project.

  19. Contract Design: Risk Management and Evaluation.

    Science.gov (United States)

    Mühlbacher, Axel C; Amelung, Volker E; Juhnke, Christin

    2018-01-12

    Effective risk adjustment is an aspect that is more and more given weight on the background of competitive health insurance systems and vital healthcare systems. The risk structure of the providers plays a vital role in Pay for Performance. A prerequisite for optimal incentive-based service models is a (partial) dependence of the agent's returns on the provider's gain level. Integrated care systems as well as accountable care organisations (ACOs) in the US and similar concepts in other countries are advocated as an effective method of improving the performance of healthcare systems. These systems outline a payment and care delivery model that intends to tie provider reimbursements to predefined quality metrics. By this the total costs of care shall be reduced. Little is known about the contractual design and the main challenges of delegating "accountability" to these new kinds of organisations and/or contracts. The costs of market utilisation are highly relevant for the conception of healthcare contracts; furthermore information asymmetries and contract-specific investments are an obstacle to the efficient operation of ACOs. A comprehensive literature review on methods of designing contracts in Integrated Care was conducted. The research question in this article focuses on how reimbursement strategies, evaluation of measures and methods of risk adjustment can best be integrated in healthcare contracting. Each integrated care contract includes challenges for both payers and providers without having sufficient empirical data on both sides. These challenges are clinical, administrative or financial nature. Risk adjusted contracts ensure that the reimbursement roughly matches the true costs resulting from the morbidity of a population. If reimbursement of care provider corresponds to the actual expenses for an individual/population the problem of risk selection is greatly reduced. The currently used methods of risk adjustment have widely differing model and forecast

  20. Market Microstructure Effects on Firm Default Risk Evaluation

    Directory of Open Access Journals (Sweden)

    Flavia Barsotti

    2016-07-01

    Full Text Available Default probability is a fundamental variable determining the credit worthiness of a firm and equity volatility estimation plays a key role in its evaluation. Assuming a structural credit risk modeling approach, we study the impact of choosing different non parametric equity volatility estimators on default probability evaluation, when market microstructure noise is considered. A general stochastic volatility framework with jumps for the underlying asset dynamics is defined inside a Merton-like structural model. To estimate the volatility risk component of a firm we use high-frequency equity data: market microstructure noise is introduced as a direct effect of observing noisy high-frequency equity prices. A Monte Carlo simulation analysis is conducted to (i test the performance of alternative non-parametric equity volatility estimators in their capability of filtering out the microstructure noise and backing out the true unobservable asset volatility; (ii study the effects of different non-parametric estimation techniques on default probability evaluation. The impact of the non-parametric volatility estimators on risk evaluation is not negligible: a sensitivity analysis defined for alternative values of the leverage parameter and average jumps size reveals that the characteristics of the dataset are crucial to determine which is the proper estimator to consider from a credit risk perspective.

  1. Approved Risk Evaluation and Mitigation Strategies

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Food and Drug Administration Amendments Act of 2007 gave FDA the authority to require a Risk Evaluation and Mitigation Strategy (REMS) from manufacturers to...

  2. Fundamentals of risk management understanding, evaluating and implementing effective risk management

    CERN Document Server

    Hopkin, Paul

    2012-01-01

    Now more than ever, organizations must plan, response and recognize all forms of risks that they face. "Fundamentals of Risk Management", now in its second edition, provides a comprehensive introduction to the subject of commercial and business risk for anyone studying for a career in risk as well as a broad range of risk professionals. It examines the key components of risk management and its application with examples to demonstrate its benefit to organisations in the public and private sector. The second edition has been completely updated to take into account the greater influence of ISO 3100, the emergence of Governance Risk and Compliance (GRC) and the wide use of the bowtie method to illustrate risk management. In addition, there is now a chapter on the skills and competencies required by an effective risk manager.

  3. The use of current risk analysis tools evaluated towards preventing external domino accidents

    NARCIS (Netherlands)

    Reniers, Genserik L L; Dullaert, W.; Ale, B. J.M.; Soudan, K.

    Risk analysis is an essential tool for company safety policy. Risk analysis consists of identifying and evaluating all possible risks. The efficiency of risk analysis tools depends on the rigueur of identifying and evaluating all possible risks. The diversity in risk analysis procedures is such that

  4. Documentation Protocols to Generate Risk Indicators Regarding Degradation Processes for Cultural Heritage Risk Evaluation

    Science.gov (United States)

    Kioussi, A.; Karoglou, M.; Bakolas, A.; Labropoulos, K.; Moropoulou, A.

    2013-07-01

    Sustainable maintenance and preservation of cultural heritage assets depends highly on its resilience to external or internal alterations and to various hazards. Risk assessment of a heritage asset's can be defined as the identification of all potential hazards affecting it and the evaluation of the asset's vulnerability (building materials and building structure conservation state).Potential hazards for cultural heritage are complex and varying. The risk of decay and damage associated with monuments is not limited to certain long term natural processes, sudden events and human impact (macroscale of the heritage asset) but is also a function of the degradation processes within materials and structural elements due to physical and chemical procedures. Obviously, these factors cover different scales of the problem. The deteriorating processes in materials may be triggered by external influences or caused because of internal chemical and/or physical variations of materials properties and characteristics. Therefore risk evaluation should be dealt in the direction of revealing the specific active decay and damage mechanism both in mesoscale [type of decay and damage] and microscale [decay phenomenon mechanism] level. A prerequisite for risk indicators identification and development is the existence of an organised source of comparable and interoperable data about heritage assets under observation. This unified source of information offers a knowledge based background of the asset's vulnerability through the diagnosis of building materials' and building structure's conservation state, through the identification of all potential hazards affecting these and through mapping of its possible alterations during its entire life-time. In this framework the identification and analysis of risks regarding degradation processes for the development of qualitative and quantitative indicators can be supported by documentation protocols. The data investigated by such protocols help

  5. DOCUMENTATION PROTOCOLS TO GENERATE RISK INDICATORS REGARDING DEGRADATION PROCESSES FOR CULTURAL HERITAGE RISK EVALUATION

    Directory of Open Access Journals (Sweden)

    A. Kioussi

    2013-07-01

    Full Text Available Sustainable maintenance and preservation of cultural heritage assets depends highly on its resilience to external or internal alterations and to various hazards. Risk assessment of a heritage asset's can be defined as the identification of all potential hazards affecting it and the evaluation of the asset's vulnerability (building materials and building structure conservation state.Potential hazards for cultural heritage are complex and varying. The risk of decay and damage associated with monuments is not limited to certain long term natural processes, sudden events and human impact (macroscale of the heritage asset but is also a function of the degradation processes within materials and structural elements due to physical and chemical procedures. Obviously, these factors cover different scales of the problem. The deteriorating processes in materials may be triggered by external influences or caused because of internal chemical and/or physical variations of materials properties and characteristics. Therefore risk evaluation should be dealt in the direction of revealing the specific active decay and damage mechanism both in mesoscale [type of decay and damage] and microscale [decay phenomenon mechanism] level. A prerequisite for risk indicators identification and development is the existence of an organised source of comparable and interoperable data about heritage assets under observation. This unified source of information offers a knowledge based background of the asset's vulnerability through the diagnosis of building materials' and building structure's conservation state, through the identification of all potential hazards affecting these and through mapping of its possible alterations during its entire life-time. In this framework the identification and analysis of risks regarding degradation processes for the development of qualitative and quantitative indicators can be supported by documentation protocols. The data investigated by such

  6. 7 CFR 319.59-3 - Articles prohibited importation pending risk evaluation.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Articles prohibited importation pending risk... Diseases § 319.59-3 Articles prohibited importation pending risk evaluation. The articles listed in...(b), pending the completion of an evaluation by APHIS of the potential pest risks associated with the...

  7. A study of risk evaluation methodology selection for the external hazards

    International Nuclear Information System (INIS)

    Kuramoto, Takahiro; Yamaguchi, Akira; Narumiya, Yosiyuki

    2014-01-01

    Since the accident at Fukushima Daiichi Nuclear Power Plant caused by the Great East Japan Earthquake in March 2011, there has been growing demands for assessing the effects of external hazards, including natural events, such as earthquake and tsunami, and external human behaviors, and taking actions to address those external hazards. The newly established Japanese regulatory requirements claim design considerations associated with external hazards. The primary objective of the risk assessment for external hazards is to establish countermeasures against such hazards rather than grasping the risk figures. Therefore, applying detailed risk assessment methods, such as probabilistic risk assessment (PRA), to all the external hazards is not always the most appropriate. Risk assessment methods can vary in types including qualitative evaluation, hazard analysis (analyzing hazard frequencies or their influence), and margin assessment. To resolve these issues, a process has been established that enables us to identify the external hazards in a comprehensive and systematic manner, which have potential risks leading to core damage and to select an appropriate evaluation method according to the risks associated with each of the external hazards. This paper discusses the comprehensive and systematic identification process for the external hazards which have potential risks leading to core damage, and the approaches of selecting an appropriate evaluation method for each external hazard. This paper also describes some applications of specific risk evaluation methods. (author)

  8. A neural network model for credit risk evaluation.

    Science.gov (United States)

    Khashman, Adnan

    2009-08-01

    Credit scoring is one of the key analytical techniques in credit risk evaluation which has been an active research area in financial risk management. This paper presents a credit risk evaluation system that uses a neural network model based on the back propagation learning algorithm. We train and implement the neural network to decide whether to approve or reject a credit application, using seven learning schemes and real world credit applications from the Australian credit approval datasets. A comparison of the system performance under the different learning schemes is provided, furthermore, we compare the performance of two neural networks; with one and two hidden layers following the ideal learning scheme. Experimental results suggest that neural networks can be effectively used in automatic processing of credit applications.

  9. Evaluation of risk effective STIs with specific application to diesels

    International Nuclear Information System (INIS)

    Vesely, W.E.; Samanta, P.K.; Ginzburg, T.

    1987-01-01

    From a risk standpoint, the objective of surveillance tests is to control the risk arising from failures which can occur while the component is on standby. At the same time, risks caused by the test from test-caused failures and test-caused degradations need also to be controlled. Risk-acceptable test intervals balance these risks in an attempt to achieve an acceptable low, overall risk. Risk and reliability approaches are presented which allow risk-acceptable test intervals to be determined for any component. To provide focus for the approaches, diesels are specifically evaluated, however, the approaches can be applied not only to diesels, but to any component with suitable data. Incorporation of the approaches in personal computer (PC) software is discussed, which can provide tools for the regulator or plant personnel for determining acceptable diesel test intervals for any plant specific or generic application. The FRANTIC III computer code was run to validate the approaches and to evaluate specific issues associated with determining risk effective test intervals for diesels. Using the approaches presented, diesel accident unavailability can be more effectively monitored and be controlled on a plant-specific or generic basis. Test intervals can be made more risk effective than they are now, producing more acceptable accident unavailabilities. The methods presented are one step toward performance-based technical specifications, which more directly control risks

  10. Contract Design: Risk Management and Evaluation

    Directory of Open Access Journals (Sweden)

    Axel C. Mühlbacher

    2018-01-01

    Full Text Available Introduction: Effective risk adjustment is an aspect that is more and more given weight on the background of competitive health insurance systems and vital healthcare systems. The risk structure of the providers plays a vital role in Pay for Performance. A prerequisite for optimal incentive-based service models is a (partial dependence of the agent’s returns on the provider’s gain level. Integrated care systems as well as accountable care organisations (ACOs in the US and similar concepts in other countries are advocated as an effective method of improving the performance of healthcare systems. These systems outline a payment and care delivery model that intends to tie provider reimbursements to predefined quality metrics. By this the total costs of care shall be reduced.  Methods: Little is known about the contractual design and the main challenges of delegating “accountability” to these new kinds of organisations and/or contracts. The costs of market utilisation are highly relevant for the conception of healthcare contracts; furthermore information asymmetries and contract-specific investments are an obstacle to the efficient operation of ACOs. A comprehensive literature review on methods of designing contracts in Integrated Care was conducted. The research question in this article focuses on how reimbursement strategies, evaluation of measures and methods of risk adjustment can best be integrated in healthcare contracting.  Results: Each integrated care contract includes challenges for both payers and providers without having sufficient empirical data on both sides. These challenges are clinical, administrative or financial nature. Risk adjusted contracts ensure that the reimbursement roughly matches the true costs resulting from the morbidity of a population. If reimbursement of care provider corresponds to the actual expenses for an individual/population the problem of risk selection is greatly reduced. The currently used methods

  11. Offshore wind turbine risk quantification/evaluation under extreme environmental conditions

    International Nuclear Information System (INIS)

    Taflanidis, Alexandros A.; Loukogeorgaki, Eva; Angelides, Demos C.

    2013-01-01

    A simulation-based framework is discussed in this paper for quantification/evaluation of risk and development of automated risk assessment tools, focusing on applications to offshore wind turbines under extreme environmental conditions. The framework is founded on a probabilistic characterization of the uncertainty in the models for the excitation, the turbine and its performance. Risk is then quantified as the expected value of some risk consequence measure over the probability distributions considered for the uncertain model parameters. Stochastic simulation is proposed for the risk assessment, corresponding to the evaluation of some associated probabilistic integral quantifying risk, as it allows for the adoption of comprehensive computational models for describing the dynamic turbine behavior. For improvement of the computational efficiency, a surrogate modeling approach is introduced based on moving least squares response surface approximations. The assessment is also extended to a probabilistic sensitivity analysis that identifies the importance of each of the uncertain model parameters, i.e. risk factors, towards the total risk as well as towards each of the failure modes contributing to this risk. The versatility and computational efficiency of the advocated approaches is finally exploited to support the development of standalone risk assessment applets for automated implementation of the probabilistic risk quantification/assessment. -- Highlights: ► A simulation-based risk quantification/assessment framework is discussed. ► Focus is on offshore wind turbines under extreme environmental conditions. ► Approach is founded on probabilistic description of excitation/system model parameters. ► Surrogate modeling is adopted for improved computational efficiency. ► Standalone risk assessment applets for automated implementation are supported

  12. Credit Risk Evaluation of Swedish SMEs : A Banking Sector Perspective

    OpenAIRE

    Hörstedt, Maria; Linjamaa, Johanna

    2015-01-01

    As a result from the latest financial crisis, the banking industry has undergone major modifications during the last years in order to limit banks’ risks. A vast majority of existing literature tends to focus upon credit risk evaluation methods and techniques mainly concerning quantitative measures and large companies. Thus, the lack of research regarding credit risk evaluation of SMEs is profound, especially considering Sweden. With the dominant market share of SMEs compared to large corpora...

  13. Evaluating shielding effectiveness for reducing space radiation cancer risks

    International Nuclear Information System (INIS)

    Cucinotta, Francis A.; Kim, Myung-Hee Y.; Ren, Lei

    2006-01-01

    We discuss calculations of probability distribution functions (PDF) representing uncertainties in projecting fatal cancer risk from galactic cosmic rays (GCR) and solar particle events (SPE). The PDFs are used in significance tests for evaluating the effectiveness of potential radiation shielding approaches. Uncertainties in risk coefficients determined from epidemiology data, dose and dose-rate reduction factors, quality factors, and physics models of radiation environments are considered in models of cancer risk PDFs. Competing mortality risks and functional correlations in radiation quality factor uncertainties are included in the calculations. We show that the cancer risk uncertainty, defined as the ratio of the upper value of 95% confidence interval (CI) to the point estimate is about 4-fold for lunar and Mars mission risk projections. For short-stay lunar missions ( 180d) or Mars missions, GCR risks may exceed radiation risk limits that are based on acceptable levels of risk. For example, the upper 95% CI exceeding 10% fatal risk for males and females on a Mars mission. For reducing GCR cancer risks, shielding materials are marginally effective because of the penetrating nature of GCR and secondary radiation produced in tissue by relativistic particles. At the present time, polyethylene or carbon composite shielding cannot be shown to significantly reduce risk compared to aluminum shielding based on a significance test that accounts for radiobiology uncertainties in GCR risk projection

  14. Risk evaluation: A cost-oriented approach

    International Nuclear Information System (INIS)

    Rogers, B.H.

    1998-01-01

    This method provides a structured and cost-oriented way to determine risks associated with loss and destruction of industrial security interests consisting of material assets and human resources. Loss and destruction are assumed to be adversary perpetrated, high-impact events in which the health and safety of people or high-value property is at risk. This concept provides a process for: (1) assessing effectiveness of all integrated protection system, which includes facility operations, safety, emergency and security systems, and (2) a qualitative prioritization scheme to determine the level of consequence relative to cost and subsequent risk. The method allows managers the flexibility to establish asset protection appropriate to programmatic requirements and priorities and to decide if funding is appropriate. The evaluation objectives are to: (1) provide for a systematic, qualitative tabletop process to estimate the potential for an undesirable event and its impact; and (2) identify ineffective protection and cost-effective solutions

  15. Risk and risk acceptance by society

    International Nuclear Information System (INIS)

    Statt, C.

    1977-01-01

    Various dimensions of risk are identified which relate to the manner in which risk is perceived and evaluated, and several self-consistent risk characteristics are explored. Factors which are thought to influence the perception of risk include the degree of personal control over the risk, the potential of episodic events, and the probable severity of injury if a risk event occurs. Risk-benefit analysis can be applied to three problems: the allocation of resources for safety expenditures, the setting of standards, and societal risk taking decisions. Calculations of benefit are needed for the third area of application, methods for the other two frequently do not require such a measure. (orig./RW) [de

  16. The radiological risks associated with the thorium fuelled HTGR fuel cycle. A comparative risk evaluation

    International Nuclear Information System (INIS)

    Dodd, D.H.; Hienen, J.F.A. van.

    1995-10-01

    This report presents the results of task B.3 of the 'Technology Assessment of the High Temperature Reactor' project. The objective of task B.3 was to evaluate the radiological risks to the general public associated with the sustainable HTGR cycle. Since the technologies to be used at several stages of this fuel cycle are still in the design phase and since a detailed specification of this fuel cycle has not yet been developed, the emphasis was on obtaining a global impression of the risk associated with a generic thorium-based HTGR fuel cycle. This impression was obtained by performing a comparative risk analysis on the basis of data given in the literature. As reference for the comparison a generic uranium fuelled LWR cycle was used. The major benefit with respect to the radiological rsiks of basing the fuel cycle around modular HTGR technology instead of the LWR technology is the increase in reactor safety. The design of the modular HTGR is expected to prevent the release of a significant amount of radioactive material to the environment, and hence early deaths in the surrounding population, during accident conditions. This implies that there is no group risk as defined in the Dutch risk management policy. The major benefit of thorium based fuel cycles over uranium based fuel cycles is the reduction in the radiological risks from unraium mining and milling. The other stages of the nuclear fuel cycle which make a significant contribution to the radiological risks are electricity generation, reprocessing and final disposal. The risks associated with the electricity generation stage are dominated by the risks from fission products, activated corrosion products and the activation products tritium and carbon-14. The risks associated with the reprocessing stage are determined by fission and activation products (including actinides). (orig./WL)

  17. The radiological risks associated with the thorium fuelled HTGR fuel cycle. A comparative risk evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Dodd, D.H.; Hienen, J.F.A. van

    1995-10-01

    This report presents the results of task B.3 of the `Technology Assessment of the High Temperature Reactor` project. The objective of task B.3 was to evaluate the radiological risks to the general public associated with the sustainable HTGR cycle. Since the technologies to be used at several stages of this fuel cycle are still in the design phase and since a detailed specification of this fuel cycle has not yet been developed, the emphasis was on obtaining a global impression of the risk associated with a generic thorium-based HTGR fuel cycle. This impression was obtained by performing a comparative risk analysis on the basis of data given in the literature. As reference for the comparison a generic uranium fuelled LWR cycle was used. The major benefit with respect to the radiological rsiks of basing the fuel cycle around modular HTGR technology instead of the LWR technology is the increase in reactor safety. The design of the modular HTGR is expected to prevent the release of a significant amount of radioactive material to the environment, and hence early deaths in the surrounding population, during accident conditions. This implies that there is no group risk as defined in the Dutch risk management policy. The major benefit of thorium based fuel cycles over uranium based fuel cycles is the reduction in the radiological risks from unraium mining and milling. The other stages of the nuclear fuel cycle which make a significant contribution to the radiological risks are electricity generation, reprocessing and final disposal. The risks associated with the electricity generation stage are dominated by the risks from fission products, activated corrosion products and the activation products tritium and carbon-14. The risks associated with the reprocessing stage are determined by fission and activation products (including actinides). (orig./WL).

  18. Societal risk approach to safeguards design and evaluation

    International Nuclear Information System (INIS)

    Murphey, W.M.; Sherr, T.S.; Bennett, C.A.

    1975-01-01

    A comprehensive rationale for safeguards design and evaluation, and a framework for continuing systematic assessment of the system's effectiveness and efficient allocation of available safeguards resources for balanced protection, were developed. The societal risk approach employed considers the likelihood of successful destructive acts involving nuclear materials or facilities and the magnitude of the effects on society. The safeguards problem is described in terms of events affecting societal risk and adversary actions. Structure of the safeguards system and the evaluation of its adequacy are discussed. Adversary characteristics are also discussed

  19. Evaluating Determinants of Environmental Risk Perception for Risk Management in Contaminated Sites

    Science.gov (United States)

    Janmaimool, Piyapong; Watanabe, Tsunemi

    2014-01-01

    Understanding the differences in the risk judgments of residents of industrial communities potentially provides insights into how to develop appropriate risk communication strategies. This study aimed to explore citizens’ fundamental understanding of risk-related judgments and to identify the factors contributing to perceived risks. An exploratory model was created to investigate the public’s risk judgments. In this model, the relationship between laypeople’s perceived risks and the factors related to the physical nature of risks (such as perceived probability of environmental contamination, probability of receiving impacts, and severity of catastrophic consequences) were examined by means of multiple regression analysis. Psychological factors, such as the ability to control the risks, concerns, experiences, and perceived benefits of industrial development were also included in the analysis. The Maptaphut industrial area in Rayong Province, Thailand was selected as a case study. A survey of 181 residents of communities experiencing different levels of hazardous gas contamination revealed rational risk judgments by inhabitants of high-risk and moderate-risk communities, based on their perceived probability of contamination, probability of receiving impacts, and perceived catastrophic consequences. However, risks assessed by people in low-risk communities could not be rationally explained and were influenced by their collective experiences. PMID:24937530

  20. Proposal of risk evaluation methodology for hazardous materials transportation

    International Nuclear Information System (INIS)

    Hartman, Luiz Carlos

    2009-01-01

    The increasing concern with the level of risk associated with the transportation of hazardous materials took some international institutions to pledge efforts in the evaluation of risk in regional level. Following this trend, the objective of this work was to analyze the most recent processes of analysis of risks from road transportation of hazardous materials. In the present work 21 methodologies of analysis of risks, developed by some authors and for diverse localities have been evaluated. Two of them, in special, have been reviewed and discussed: a method recently developed by the Swiss Federal Institute of Technology (Nicolet-Monnier and Gheorghe, 1996) and the strategy delineated by the Center for Chemical Process Safety CCPS (1995), taking into consideration the estimate of the individual and social risk. Also, the models of Harwood et al. (1990) and of Ramos (1997), adapted by Hartman (2003) have been applied to the reality of the roads of the state of Sao Paulo. The extension of these methodologies was explored, in order to find its advantages and disadvantages. As a study case the present work considered the ammonia transportation throughout two routes evaluating the reality of the roads of the state of Sao Paulo, including a significant parcel of evaluation in a densely populated area, getting the results using risk, at least, one of the methodologies mentioned above. The innovation proposed by this work was the research, the development and the introduction of two variables to the model considered by Harwood et al. (1990). These variables that influence in the value of the risk are: the age of the driver of truck and the zone of impact that is function type of product, period of the day where the transport was carried and the volume that has been transported. The aim of the proposed modifications is to let the value of the risk more sensible in relation to the type of the product carried and the age of the truck driver. The main related procedural stages

  1. Risk evaluation for structures

    International Nuclear Information System (INIS)

    Freudenthal, A.M.; Schueller, G.I.

    1976-01-01

    The basic principles of the risk analysis, which is based on classical statistics is discussed. The significance of the Asymptotic (Extreme Value) distributions as well as the method of basing the level of acceptable risk on economical optimization procedures is pointed out. The application of the risk analysis to special type structures such as fixed offshore platforms, television towers, reactor containments and the reliability of reactor components under creep and fatigue load is elaborated by carrying out numerical examples. (orig./HP) [de

  2. Integration of industrial risk in regional policy management. Possibilities of evaluation

    International Nuclear Information System (INIS)

    Hubert, Philippe; Pages, Pierre

    1990-02-01

    Since the responsibility for risk management depends more and more on regional factors, evaluation methods and management regulations are not developed enough. This study start from the fact that an important methods exist for evaluation transport of dangerous materials in cities, risk analysis and emergency plans related to classified installations, management of quality of water, 'chronic' industrial risks at local and regional level, probabilistic estimation for industrial plants. The objective is in fact to show what risk analysis could bring to the municipality, the city or the region [fr

  3. U.S. Department of energy worker health risk evaluation methodology for assessing risks associated with environmental restoration and waste management

    International Nuclear Information System (INIS)

    Blaylock, B.P.; Legg, J.; Travis, C.C.; Scofield, P.A.

    1995-06-01

    This document describes a worker health risk evaluation methodology for assessing risks associated with Environmental Restoration (ER) and Waste Management (WM). The methodology is appropriate for estimating worker risks across the Department of Energy (DOE) Complex at both programmatic and site-specific levels. This document supports the worker health risk methodology used to perform the human health risk assessment portion of the DOE Programmatic Environmental Impact Statement (PEIS) although it has applications beyond the PEIS, such as installation-wide worker risk assessments, screening-level assessments, and site-specific assessments

  4. U.S. Department of Energy worker health risk evaluation methodology for assessing risks associated with environmental restoration and waste management

    Energy Technology Data Exchange (ETDEWEB)

    Blaylock, B.P.; Legg, J.; Travis, C.C. [Oak Ridge National Lab., TN (United States). Center for Risk Management; Simek, M.A.; Sutherland, J. [Univ. of Tennessee, Knoxville, TN (United States); Scofield, P.A. [Office of Environmental Compliance and Documentation (United States)

    1995-06-01

    This document describes a worker health risk evaluation methodology for assessing risks associated with Environmental Restoration (ER) and Waste Management (WM). The methodology is appropriate for estimating worker risks across the Department of Energy (DOE) Complex at both programmatic and site-specific levels. This document supports the worker health risk methodology used to perform the human health risk assessment portion of the DOE Programmatic Environmental Impact Statement (PEIS) although it has applications beyond the PEIS, such as installation-wide worker risk assessments, screening-level assessments, and site-specific assessments.

  5. Risk evaluation and mitigation strategies: a focus on belatacept.

    Science.gov (United States)

    Sam, Teena; Gabardi, Steven; Tichy, Eric M

    2013-03-01

    To review the elements and components of the risk evaluation and mitigation strategies (REMS) for the costimulation blocker belatacept and associated implications for health care providers working with transplant recipients. The MEDLINE and EMBASE databases (January 1990 to March 2012) were searched by using risk evaluation and mitigation strategies, REMS, belatacept, and organ transplant as search terms (individual organs were also searched). Retrieved articles were supplemented with analysis of information obtained from the Federal Register, the Food and Drug Administration, and the manufacturer of belatacept. REMS are risk-management strategies implemented to ensure that a product's benefits outweigh its known safety risks. Although belatacept offers a novel strategy in maintenance immunosuppression and was associated with superior renal function compared with cyclosporine in phase 2 and 3 trials, belatacept is also associated with increased risk of posttransplant lymphoproliferative disorder and central nervous system infections. The Food and Drug Administration required development of a REMS program as part of belatacept's approval process to ensure safe and appropriate use of the medication and optimization of its risk-benefit profile. Elements of the belatacept REMS include a medication guide that must be dispensed with each infusion and a communication plan. In the management of a complex population of patients, it is essential that those who care for transplant recipients, and patients, recognize the implications of potential and known risks of belatacept. The REMS program aims to facilitate careful selection and education of patients and vigilant monitoring.

  6. Credit risk evaluation based on social media.

    Science.gov (United States)

    Yang, Yang; Gu, Jing; Zhou, Zongfang

    2016-07-01

    Social media has been playing an increasingly important role in the sharing of individuals' opinions on many financial issues, including credit risk in investment decisions. This paper analyzes whether these opinions, which are transmitted through social media, can accurately predict enterprises' future credit risk. We consider financial statements oriented evaluation results based on logit and probit approaches as the benchmarks. We then conduct textual analysis to retrieve both posts and their corresponding commentaries published on two of the most popular social media platforms for financial investors in China. Professional advice from financial analysts is also investigated in this paper. We surprisingly find that the opinions extracted from both posts and commentaries surpass opinions of analysts in terms of credit risk prediction. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. Evaluation Method of Collision Risk by Using True Motion

    Directory of Open Access Journals (Sweden)

    Hayama Imazu

    2017-03-01

    Full Text Available It is necessary to develop a useful application to use big data like as AIS for safety and efficiency of ship operation. AIS is very useful system to collect targets information, but this information is not effective use yet. The evaluation method of collision risk is one of the cause disturb. Usually the collision risk of ship is evaluated by the value of the Closest Point of Approach (CPA which is related to a relative motion. So, it becomes difficult to find out a safety pass in a congested water. Here, Line of Predicted Collision (LOPC and Obstacle Zone by Target (OZT for evaluation of collision risk are introduced, these values are related to a true motion and it became visible of dangerous place, so it will make easy to find out a safety pass in a congested water.

  8. Risk Evaluation for CO{sub 2} Geosequestration in the Knox Supergroup

    Energy Technology Data Exchange (ETDEWEB)

    Leetaru, Hannes

    2014-01-31

    This report describes a process and provides seed information for identifying and evaluating risks pertinent to a hypothetical carbon dioxide (CO{sub 2}) capture and sequestration (CCS) project. In the envisioned project, the target sequestration reservoir rock is the Potosi Formation of the Knox Supergroup. The Potosi is identified as a potential target formation because (1) at least locally, it contains vuggy to cavernous layers that have very high porosity, and (2) it is present in areas where the deeper Mt. Simon Sandstone (a known potential reservoir unit) is absent or nonporous. The key report content is discussed in Section 3.3, which describes two lists of Features, Events, and Processes (FEPs) that should be considered during the design stage of such a project. These lists primarily highlight risk elements particular to the establishment of the Potosi as the target formation in general. The lists are consciously incomplete with respect to risk elements that would be relevant for essentially all CCS projects regardless of location or geology. In addition, other risk elements specific to a particular future project site would have to be identified. Sources for the FEPs and scenarios listed here include the iconic Quintessa FEPs list developed for the International Energy Agency Greenhouse Gas (IEAGHG) Programme; previous risk evaluation projects executed by Schlumberger Carbon Services; and new input solicited from experts currently working on aspects of CCS in the Knox geology. The projects used as sources of risk information are primarily those that have targeted carbonate reservoir rocks similar in age, stratigraphy, and mineralogy to the Knox-Potosi. Risks of using the Potosi Formation as the target sequestration reservoir for a CCS project include uncertainties about the levels of porosity and permeability of that rock unit; the lateral consistency and continuity of those properties; and the ability of the project team to identify suitable (i

  9. Evaluation of risk prioritization and budget allocation methods for pollution prevention activities

    International Nuclear Information System (INIS)

    Daniels, J.; Jones, E.; Lmont, A.; Ladmn, T.; Watz, J.

    1997-01-01

    This study reviews the structure of two main risk prioritization budget allocation methods developed by the DOE Risk-Based Priority Mode (RPM) and Management Evaluation Matrix (MEM). It identifies potential augmentations to the process that will address both risk reduction and cost-effective investments of finite resources for future Environmental Management activities. The evaluation was performed in accordance with the EM ten-year vision and principles for site cleanup. The evaluation and recommendations in this report strive to reflect four key principles, namely to eliminate the most urgent risks, reduce mortgage and support costs to make funds available for further risk reduction, protect worker health and safety, and reduce the generation of wastes

  10. Risk evaluation of accident management strategies

    International Nuclear Information System (INIS)

    Dingman, S.; Camp, A.

    1992-01-01

    The use of Probabilistic Risk Assessment (PRA) methods to evaluate accident management strategies in nuclear power plants discussed in this paper. The PRA framework allows an integrated evaluation to be performed to give the full implications of a particular strategy. The methodology is demonstrated for a particular accident management strategy, intentional depressurization of the reactor coolant system to avoid containment pressurization during the ejection of molten debris at vessel breach

  11. An approach to assessing risk in coalbed methane prospect evaluation

    International Nuclear Information System (INIS)

    Vanorsdale, C.R.

    1991-01-01

    The economic evaluation of drilling prospects requires assessing the degree of risk involved and its impact on reserve estimates. In developed areas, risk can be determined in a fairly straightforward manner. In remote wildcat areas, risk can almost never be adequately identified or quantified. Between these extremes lie complex reservoirs -- reservoirs to heterogeneous that each well drilled could exhibit production characteristics unlike those of its neighbors. This paper illustrates the use of a risk assessment methodology in a case study of Fruitland coal prospects in the San Juan Basin of New Mexico. This approach could be applied to coalbed methane prospects or any unconventional or highly heterogeneous reservoir with appropriate modification. The utility of this approach is made apparent in a graphical analysis that relates reserves, rate of return and payout time for managerial or financial presentation. This graphical technique and the underlying risk assessment were used to aid a conservative management team in evaluating participation in a multi-well coalbed project

  12. Evaluation of air pollution-related risks for Austrian mountain forests

    International Nuclear Information System (INIS)

    Smidt, Stefan; Herman, Friedl

    2004-01-01

    The present paper describes air pollution status and evaluation of risks related to effects of phytotoxic pollutants in the Austrian mountain forests. The results are based on Austrian networks (Forest Inventory, Forest Damage Monitoring System, Austrian Bioindicator Grid), the Austrian sample plots of the European networks of the UN-ECE (ICP Forests, Level I and Level II) and interdisciplinary research approaches. Based on the monitoring data and on modelling and mapping of Critical Thresholds, the evaluation of risk factors was possible. Cause-effect relationships between air pollution and tree responses were shown by tree-physiological measurements. Sulfur impact, proton and lead input, concentrations of nitrogen oxides, nitrogen input and ozone were evaluated. The risk was demonstrated at a regional and large-scale national level. Especially the increasing O 3 level and the accumulation of Pb with altitude present most serious risk for mountain forests. - Despite strong reduction of emissions in Europe, pollutants are still a potential stress factor, especially for sensitive mountain forest ecosystems in Austria

  13. Evaluation of Cardiovascular Risk Scores Applied to NASA's Astronant Corps

    Science.gov (United States)

    Jain, I.; Charvat, J. M.; VanBaalen, M.; Lee, L.; Wear, M. L.

    2014-01-01

    In an effort to improve cardiovascular disease (CVD) risk prediction, this analysis evaluates and compares the applicability of multiple CVD risk scores to the NASA Astronaut Corps which is extremely healthy at selection.

  14. Multi Criteria Evaluation Module for RiskChanges Spatial Decision Support System

    Science.gov (United States)

    Olyazadeh, Roya; Jaboyedoff, Michel; van Westen, Cees; Bakker, Wim

    2015-04-01

    Multi-Criteria Evaluation (MCE) module is one of the five modules of RiskChanges spatial decision support system. RiskChanges web-based platform aims to analyze changes in hydro-meteorological risk and provides tools for selecting the best risk reduction alternative. It is developed under CHANGES framework (changes-itn.eu) and INCREO project (increo-fp7.eu). MCE tool helps decision makers and spatial planners to evaluate, sort and rank the decision alternatives. The users can choose among different indicators that are defined within the system using Risk and Cost Benefit analysis results besides they can add their own indicators. Subsequently the system standardizes and prioritizes them. Finally, the best decision alternative is selected by using the weighted sum model (WSM). The Application of this work is to facilitate the effect of MCE for analyzing changing risk over the time under different scenarios and future years by adopting a group decision making into practice and comparing the results by numeric and graphical view within the system. We believe that this study helps decision-makers to achieve the best solution by expressing their preferences for strategies under future scenarios. Keywords: Multi-Criteria Evaluation, Spatial Decision Support System, Weighted Sum Model, Natural Hazard Risk Management

  15. Communicating radon risk effectively: a mid-course evaluation. Interim report

    International Nuclear Information System (INIS)

    Smith, V.K.; Desvousges, W.H.; Fisher, A.; Johnson, F.R.

    1987-07-01

    A panel of 2300 homeowners was divided into subgroups to test the effectiveness of six alternative ways of explaining the risk from naturally occurring radon gas. The research design focused on two dimensions: qualitative vs. quantitative and directive vs. evaluative. These characteristics led to 4 experimental booklets, which were compared with EPA's Citizen's Guide and a one-page fact sheet. The evaluation examined how much people learned about radon; whether they could form risk perceptions consistent with their home's measured radon level; and whether they felt they had enough information to make a decision about mitigation. The fact sheet did not perform well on any of these evaluation criteria. None of the five booklets clearly was best for all 3 evaluation criteria; the report discusses the implications for designing an effective radon-risk communication program

  16. Identifying and evaluating E-procurement in supply chain risk by Fuzzy MADM

    Directory of Open Access Journals (Sweden)

    Mostafa Memarzade

    2012-08-01

    Full Text Available E-procurement risks has emerged as an important issue for researchers and practitioners because mitigating supply chain risk helps improve firms’ as well as supply chains’ performance. E-marketplaces have been steadily growing and there have been significant interest in e-business research. There are different risks and uncertainties involved with E-marketplaces, which jeopardizes the sector but we have had a large amount of hype and the business still continue to grow. The primary aim of this study is to identify E-procurement risks and evaluate them using a fuzzy AHP framework. We contribute E-procurement risk by identifying 13 critical criteria and determine four important ones including the extent of acceptable information, interrelationship risk, lack of honesty in relationships and product quality and safety for evaluating suppliers’ risk.

  17. Risk communication. Risk studies in social science; Risk communication. Risk kenkyu eno shakai kagakuteki approach

    Energy Technology Data Exchange (ETDEWEB)

    Asami, M. [Keio Univ., Tokyo (Japan)

    1995-11-05

    It is recently, that is, in and after the 1980s that socio-scientific approaches began to be made to studies on `risk`. It started to be made clear that the progress of the scientific technology does not necessarily bring about good news to man, and obvious estrangement has begun to appear between scientific evaluation and social evaluation of risk. The subject of risk communication (RC) study is to tackle a proposition whether the estrangement will continue to exist as estrangement or the estrangement can be made smaller by any means. This paper explains the recent trend of the study. For example, as for how each individual thinks about risk, that is, the risk perception, a new framework is trially being constructed by introduction of the quantitative method using psychometrics. A duty of RC is to serve to bridge the gap between scientific technology and society which are controlled by values which are incompatible with each other. Therefore, RC will be more and more important. 15 refs., 1 fig., 2 tabs.

  18. Stochastic evaluation of tsunami inundation and quantitative estimating tsunami risk

    International Nuclear Information System (INIS)

    Fukutani, Yo; Anawat, Suppasri; Abe, Yoshi; Imamura, Fumihiko

    2014-01-01

    We performed a stochastic evaluation of tsunami inundation by using results of stochastic tsunami hazard assessment at the Soma port in the Tohoku coastal area. Eleven fault zones along the Japan trench were selected as earthquake faults generating tsunamis. The results show that estimated inundation area of return period about 1200 years had good agreement with that in the 2011 Tohoku earthquake. In addition, we evaluated quantitatively tsunami risk for four types of building; a reinforced concrete, a steel, a brick and a wood at the Soma port by combining the results of inundation assessment and tsunami fragility assessment. The results of quantitative estimating risk would reflect properly vulnerability of the buildings, that the wood building has high risk and the reinforced concrete building has low risk. (author)

  19. Literature Review on Modeling Cyber Networks and Evaluating Cyber Risks.

    Energy Technology Data Exchange (ETDEWEB)

    Kelic, Andjelka; Campbell, Philip L

    2018-04-01

    The National Infrastructure Simulations and Analysis Center (NISAC) conducted a literature review on modeling cyber networks and evaluating cyber risks. The literature review explores where modeling is used in the cyber regime and ways that consequence and risk are evaluated. The relevant literature clusters in three different spaces: network security, cyber-physical, and mission assurance. In all approaches, some form of modeling is utilized at varying levels of detail, while the ability to understand consequence varies, as do interpretations of risk. This document summarizes the different literature viewpoints and explores their applicability to securing enterprise networks.

  20. Evaluation of the field relevance of several injury risk functions.

    Science.gov (United States)

    Prasad, Priya; Mertz, Harold J; Dalmotas, Danius J; Augenstein, Jeffrey S; Diggs, Kennerly

    2010-11-01

    An evaluation of the four injury risk curves proposed in the NHTSA NCAP for estimating the risk of AIS>= 3 injuries to the head, neck, chest and AIS>=2 injury to the Knee-Thigh-Hip (KTH) complex has been conducted. The predicted injury risk to the four body regions based on driver dummy responses in over 300 frontal NCAP tests were compared against those to drivers involved in real-world crashes of similar severity as represented in the NASS. The results of the study show that the predicted injury risks to the head and chest were slightly below those in NASS, and the predicted risk for the knee-thigh-hip complex was substantially below that observed in the NASS. The predicted risk for the neck by the Nij curve was greater than the observed risk in NASS by an order of magnitude due to the Nij risk curve predicting a non-zero risk when Nij = 0. An alternative and published Nte risk curve produced a risk estimate consistent with the NASS estimate of neck injury. Similarly, an alternative and published chest injury risk curve produced a risk estimate that was within the bounds of the NASS estimates. No published risk curve for femur compressive load could be found that would give risk estimates consistent with the range of the NASS estimates. Additional work on developing a femur compressive load risk curve is recommended.

  1. Dynamic performances of the fallout radionuclides in the environment and related health risk evaluation

    International Nuclear Information System (INIS)

    Morisawa, Shinsuke

    2003-01-01

    The framework was developed for evaluating the cancer induction mortality risk due to the prolonged exposure to the fallout Sr-90 in the environment, which was released by the atmospheric nuclear detonation tests, through dietary intake by considering the effect of foods and feeds import to Japan. The risk evaluation framework presented was composed of three sub-models: the model foe evaluation of the global circulation of Sr-90, the model for evaluation of Sr-90 concentration in foods and dietary intake, and the model for the cancer induction mortality risk. The mortality risk by the radiation-induced leukemia was evaluated based on the NUREG/CR-4214 model. The model was applied on the reference Japanese for past half century to evaluate the historical variation of the health risks. The new framework is presented and discussed on their feasibility to apply on the health risk evaluation due to the low-level and prolonged exposure to radionuclides in the environment. The possibility to use some kind of bio-markers are discussed to evaluate the potential health risk in advance before the risk will be actually detected. (author)

  2. Credit Risk Evaluation System: An Artificial Neural Network Approach

    African Journals Online (AJOL)

    On the other hand, this kind of bank's activity is connected with high risk as big amount of bad decisions may even cause bankruptcy. The key problem consists of distinguishing good (that surely repay) and bad (that likely default) credit applicants. Credit risk evaluation is an important and interesting management science ...

  3. Diagnosis and Tests: Evaluating a Fall or Risk of Falling

    Science.gov (United States)

    ... as a physical therapist, who can evaluate your fall risk. If your healthcare provider concludes that you are ... to check for things that can impact your fall risk, such as electrolyte balance and the possibility of ...

  4. Pest risk assessment of Monilinia fructicola for the EU territory and identification and evaluation of risk management options

    DEFF Research Database (Denmark)

    Baker, R.; Candresse, T.; Dormannsné Simon, E.

    2011-01-01

    The EFSA Panel on Plant Health has delivered a pest risk assessment on the risk posed by Monilinia fructicola to the EU territory and has identified risk management options and evaluated their effectiveness in reducing the risk to plant health posed by this organism. The Panel has also analysed...... the effectiveness of the special requirements presently listed in Annex IV, Part A, Section I of Council Directive 2000/29/EC, in reducing the risk of introduction of this pest into the EU territory. The Panel concluded that the main pathways for entry into the EU territory are plant material for propagation...... of the risk assessment area. Cultural practices and control measures currently applied and competition with other Monilinia species cannot prevent the establishment of M. fructicola. The probability of spread is very likely because of the multiple ways of dispersal of the pest. The overall impact...

  5. Evaluating Risk Communication After the Fukushima Disaster Based on Nudge Theory.

    Science.gov (United States)

    Murakami, Michio; Tsubokura, Masaharu

    2017-03-01

    Using nudge theory and some examples of risk communication that followed the Fukushima disaster, this article discusses the influences and justifications of risk communication, in addition to how risk communication systems are designed. To assist people in making decisions based on their own value systems, we provide three suggestions, keeping in mind that people can be influenced (ie, "nudged") depending on how risk communication takes place: (1) accumulate knowledge on the process of evaluating how the method of risk communication and a system's default design could impact people; (2) clarify the purpose and outcomes of risk communication; and (3) see what risk communication might be ethically unjustifiable. Quantitative studies on risk communication and collective narratives will provide some ideas for how to design better risk communication systems and to help people make decisions. Furthermore, we have shown examples of unjustifiable risk communication.

  6. Evaluating intergenerational risks: Probabillity adjusted rank-discounted utilitarianism

    OpenAIRE

    Asheim, Geir B.; Zuber, Stéphane

    2015-01-01

    Climate policies have stochastic consequences that involve a great number of generations. This calls for evaluating social risk (what kind of societies will future people be born into) rather than individual risk (what will happen to people during their own lifetimes). As a response we propose and axiomatize probability adjusted rank-discounted critical-level generalized utilitarianism (PARDCLU), through a key axiom that requires that the social welfare order both be ethical and satisfy first...

  7. Evaluation of Risk Perception and Risk-Comparison Information Regarding Dietary Radionuclides after the 2011 Fukushima Nuclear Power Plant Accident.

    Science.gov (United States)

    Murakami, Michio; Nakatani, Jun; Oki, Taikan

    2016-01-01

    In the wake of the 2011 Fukushima Daiichi Nuclear Power Station accident, to facilitate evidence-based risk communication we need to understand radiation risk perception and the effectiveness of risk-comparison information. We measured and characterized perceptions of dread risks and unknown risks regarding dietary radionuclides in residents of Fukushima, Tokyo, and Osaka to identify the primary factors among location, evacuation experience, gender, age, employment status, absence/presence of spouse, children and grandchildren, educational background, humanities/science courses, smoking habits, and various types of trustworthy information sources. We then evaluated the effects of these factors and risk-comparison information on multiple outcomes, including subjective and objective understanding, perceived magnitude of risk, perceived accuracy of information, backlash against information, and risk acceptance. We also assessed how risk-comparison information affected these multiple outcomes for people with high risk perception. Online questionnaires were completed by people (n = 9249) aged from 20 to 69 years in the three prefectures approximately 5 years after the accident. We gave each participant one of 15 combinations of numerical risk data and risk-comparison information, including information on standards, smoking-associated risk, and cancer risk, in accordance with Covello's guidelines. Dread-risk perception among Fukushima residents with no experience of evacuation was much lower than that in Osaka residents, whereas evacuees had strikingly higher dread-risk perception, irrespective of whether their evacuation had been compulsory or voluntary. We identified location (distance from the nuclear power station), evacuation experience, and trust of central government as primary factors. Location (including evacuation experience) and trust of central government were significantly associated with the multiple outcomes above. Only information on "cancer risk from

  8. Risk evaluation and control strategies for indoor radon: a brief discussion

    International Nuclear Information System (INIS)

    Nero, A.V. Jr.

    1994-01-01

    Average risks of death estimated for radon are larger than those for many exposures in the outdoor environment, but similar to some in industrial settings. However, the indoor environment differs in regard to cost, benefit, responsibility, and distribution of risks from the outdoor and occupational settings, where frameworks for setting risk-limiting objectives and strategies have already been developed substantially. This indicates the need to develop a conceptual framework for evaluating risks in the indoor environment, within which the objectives of radon control strategies can be sensibly chosen. Nevertheless, the range of estimated radon risks and of recent radon control strategies suggest near-term elements of any strategy, i.e. accurate and effective public information, as well as reliable monitoring and control capabilities, and a focus on areas where most high residential levels occur. Developing a conceptual framework for evaluating indoor risks will permit the formulation of suitable aims on average indoor exposures and lower exposure situations. (author)

  9. Risk control and the minimum significant risk

    International Nuclear Information System (INIS)

    Seiler, F.A.; Alvarez, J.L.

    1996-01-01

    Risk management implies that the risk manager can, by his actions, exercise at least a modicum of control over the risk in question. In the terminology of control theory, a management action is a control signal imposed as feedback on the system to bring about a desired change in the state of the system. In the terminology of risk management, an action is taken to bring a predicted risk to lower values. Even if it is assumed that the management action taken is 100% effective and that the projected risk reduction is infinitely well known, there is a lower limit to the desired effects that can be achieved. It is based on the fact that all risks, such as the incidence of cancer, exhibit a degree of variability due to a number of extraneous factors such as age at exposure, sex, location, and some lifestyle parameters such as smoking or the consumption of alcohol. If the control signal is much smaller than the variability of the risk, the signal is lost in the noise and control is lost. This defines a minimum controllable risk based on the variability of the risk over the population considered. This quantity is the counterpart of the minimum significant risk which is defined by the uncertainties of the risk model. Both the minimum controllable risk and the minimum significant risk are evaluated for radiation carcinogenesis and are shown to be of the same order of magnitude. For a realistic management action, the assumptions of perfectly effective action and perfect model prediction made above have to be dropped, resulting in an effective minimum controllable risk which is determined by both risk limits. Any action below that effective limit is futile, but it is also unethical due to the ethical requirement of doing more good than harm. Finally, some implications of the effective minimum controllable risk on the use of the ALARA principle and on the evaluation of remedial action goals are presented

  10. Evaluation of Total Cardiovascular Risk in Patients with Hypertension and Impaired Glucose Tolerance

    Directory of Open Access Journals (Sweden)

    I.V. Cherniavska

    2016-11-01

    Full Text Available Aim. Timely reveal of the patients at high risk of cardiovascular diseases for whom earlier intervention for cardiovascular risk correction is the most effective. Materials and methods. Seventy patients aged 30–55 years old with stage 2 hypertension, impaired glucose tolerance (IGT and high cardiovascular risk were examined according to Framingham criteria. Cardiovascular risk was compared by SCORE and PROCAM results. Results. Percentage ratio of males with high cardiovascular risk was higher by 52.3 % in comparison to females by SCORE and by 2.3 % in comparison to females by PROCAM. Males did not present any significant discrepancy by evaluation of cardiovascular risk by both scores unlike females. Obtained results showed that total cardiovascular risk in females was twofold higher by PROCAM compared to SCORE scale. Conclusions. Total cardiovascular risk level in patients with stage 2 hypertension and IGT is influenced by age, systolic blood pressure level, smoking, lipid storage disease and carbohydrate metabolism disorder. When we evaluate total cardiovascular risk, we should not be limited only by determination of factors determined in SCORE. It is reasonable to evaluate risk factors by PROCAM, too, especially for females.

  11. A risk based approach to firm evaluation applied to Dutch industries

    NARCIS (Netherlands)

    E.M. Vermeulen (Erik); J. Spronk (Jaap); D. van der Wijst (Nico)

    1992-01-01

    textabstractIn this paper, a method is developed to evaluate firms on the basis of the risks they face. In accordance with the multi-factor method, risk is represented as a vector of sensitivities for unexpected changes of risk factors. Subsequently, the sensitivities themselves are related to firm

  12. User's guide to the repository intrusion risk evaluation code INTRUDE

    International Nuclear Information System (INIS)

    Nancarrow, D.J.; Thorne, M.C.

    1986-05-01

    The report, commissioned by the Department of the Environment as part of its radioactive waste management research programme, constitutes the user's guide to the repository intrusion risk evaluation code INTRUDE. It provides an explanation of the mathematical basis of the code, the database used and the operation of the code. INTRUDE is designed to facilitate the estimation of individual risks arising from the possibility of intrusion into shallow land burial facilities for radioactive wastes. It considers a comprehensive inventory of up to 65 long-lived radionuclides and produces risk estimates for up to 20 modes of intrusion and up to 50 times of evaluation. (author)

  13. Risk-adjusted performance evaluation in three academic thoracic surgery units using the Eurolung risk models.

    Science.gov (United States)

    Pompili, Cecilia; Shargall, Yaron; Decaluwe, Herbert; Moons, Johnny; Chari, Madhu; Brunelli, Alessandro

    2018-01-03

    The objective of this study was to evaluate the performance of 3 thoracic surgery centres using the Eurolung risk models for morbidity and mortality. This was a retrospective analysis performed on data collected from 3 academic centres (2014-2016). Seven hundred and twenty-one patients in Centre 1, 857 patients in Centre 2 and 433 patients in Centre 3 who underwent anatomical lung resections were analysed. The Eurolung1 and Eurolung2 models were used to predict risk-adjusted cardiopulmonary morbidity and 30-day mortality rates. Observed and risk-adjusted outcomes were compared within each centre. The observed morbidity of Centre 1 was in line with the predicted morbidity (observed 21.1% vs predicted 22.7%, P = 0.31). Centre 2 performed better than expected (observed morbidity 20.2% vs predicted 26.7%, P models were successfully used as risk-adjusting instruments to internally audit the outcomes of 3 different centres, showing their applicability for future quality improvement initiatives. © The Author(s) 2018. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  14. Risk management study for the retired Hanford Site facilities: Risk management executive summary

    International Nuclear Information System (INIS)

    Coles, G.A.; Shultz, M.V.; Taylor, W.E.

    1994-02-01

    This document provides a cost-comparison evaluation for implementing certain risk-reduction measures and their effect on the overall risk of the 100 and 200 Area retired, surplus facilities. The evaluation is based on conditions that existed at the time the risk evaluation team performed facility investigations, and does not acknowledge risk-reduction measures that occurred soon after risk identification. This evaluation is one part of an overall risk management study for these facilities. The retired facilities investigated for this evaluation are located in the 100 and 200 Areas of the 1450-km 2 Hanford Site. The Hanford Site is a semiarid tract of land in southeastern Washington State. The nearest population center is Richland, Washington, (population 32,000) 30 km southeast of the 200 Area. This document is the first in a four volume series that comprise the risk management study for the retired, surplus facilities. Volume 2 is the risk evaluation work procedure; volume 3 provides the results for the risk evaluation; and volume 4 is the risk-reduction cost comparison

  15. Two-scale evaluation of remediation technologies for a contaminated site by applying economic input-output life cycle assessment: risk-cost, risk-energy consumption and risk-CO2 emission.

    Science.gov (United States)

    Inoue, Yasushi; Katayama, Arata

    2011-09-15

    A two-scale evaluation concept of remediation technologies for a contaminated site was expanded by introducing life cycle costing (LCC) and economic input-output life cycle assessment (EIO-LCA). The expanded evaluation index, the rescue number for soil (RN(SOIL)) with LCC and EIO-LCA, comprises two scales, such as risk-cost, risk-energy consumption or risk-CO(2) emission of a remediation. The effectiveness of RN(SOIL) with LCC and EIO-LCA was examined in a typical contamination and remediation scenario in which dieldrin contaminated an agricultural field. Remediation was simulated using four technologies: disposal, high temperature thermal desorption, biopile and landfarming. Energy consumption and CO(2) emission were determined from a life cycle inventory analysis using monetary-based intensity based on an input-output table. The values of RN(SOIL) based on risk-cost, risk-energy consumption and risk-CO(2) emission were calculated, and then rankings of the candidates were compiled according to RN(SOIL) values. A comparison between three rankings showed the different ranking orders. The existence of differences in ranking order indicates that the scales would not have reciprocal compatibility for two-scale evaluation and that each scale should be used independently. The RN(SOIL) with LCA will be helpful in selecting a technology, provided an appropriate scale is determined. Copyright © 2011 Elsevier B.V. All rights reserved.

  16. Experimental approaches for evaluating the invasion risk of biofuel crops

    International Nuclear Information System (INIS)

    Luke Flory, S; Sollenberger, Lynn E; Lorentz, Kimberly A; Gordon, Doria R

    2012-01-01

    There is growing concern that non-native plants cultivated for bioenergy production might escape and result in harmful invasions in natural areas. Literature-derived assessment tools used to evaluate invasion risk are beneficial for screening, but cannot be used to assess novel cultivars or genotypes. Experimental approaches are needed to help quantify invasion risk but protocols for such tools are lacking. We review current methods for evaluating invasion risk and make recommendations for incremental tests from small-scale experiments to widespread, controlled introductions. First, local experiments should be performed to identify conditions that are favorable for germination, survival, and growth of candidate biofuel crops. Subsequently, experimental introductions in semi-natural areas can be used to assess factors important for establishment and performance such as disturbance, founder population size, and timing of introduction across variable habitats. Finally, to fully characterize invasion risk, experimental introductions should be conducted across the expected geographic range of cultivation over multiple years. Any field-based testing should be accompanied by safeguards and monitoring for early detection of spread. Despite the costs of conducting experimental tests of invasion risk, empirical screening will greatly improve our ability to determine if the benefits of a proposed biofuel species outweigh the projected risks of invasions. (letter)

  17. Evaluation of thermal risk assessment

    International Nuclear Information System (INIS)

    Loos, J.J.; Perry, E.S.

    1993-01-01

    Risk assessment was done in 1983 to estimate the ecological hazard of increasing the generating load and thermal output of an electric generating station. Subsequently, long-term monitoring in the vicinity of the station allowed verification of the predictions made in the risk assessment. This presentation will review the efficacy of early risk assessment methods in producing useful predictions from a resource management point of view. In 1984, the Chalk Point Generating facility of the Potomac Electric Power Company increased it's median generating load by 100%. Prior to this operational change, the Academy of Natural Sciences of Philadelphia synthesized site specific data, model predictions, and results from literature to assess the risk of additional waste heat to the Patuxent River subestuary of Chesapeake Bay. Risk was expressed as the number of days per year that various species of fish and the blue crab would be expected to avoid the discharge vicinity. Accuracy of these predictions is assessed by comparing observed fish and crab distributions and their observed frequencies of avoidance to those predicted. It is concluded that the predictions of this early risk assessment were sufficiently accurate to produce a reliable resource management decision

  18. MODERN RISK MEASURES FOR INDIVIDUAL HIGHER EDUCATION INVESTMENT RISK EVALUATION

    Directory of Open Access Journals (Sweden)

    Vona Mate

    2014-07-01

    Full Text Available One of the reasons why people get degree and participate in organized education is that they want to raise their human capital or signal their inner abilities to future employers by sorting themselves out. In both cases they can expect return to their investment, because they can expect higher life-time earnings than those who do not have degree. In this paper we will refer this activity as higher education investment or education investment. In this paper the investment of the state into educating their citizens will not be considered. The question of this paper will develop the findings of Vona (2014. I suggested to introduce modern risk measures because individual risk-taking became a serious question. It was considered that modern risk measures can help to solve some issues with the relation of investment and risk. However before applying some measures from a different field of science, namely investment finance and financial mathematics, to another, economics of education, there must be a very careful consideration, because there are debate over these measures applicability even on their field of science. Value at Risk is not coherent and Expected Shortfall is only one of a great deal of possible tail loss measures. For this reason it will be discussed in detail how should we should adopt the measures, what kind of data is necessary for calculating this risk measures and what kind of new insight they can bring. With the aid of a numerical example it will be shown that with expected shortfall measure we can reflect some large losses, and potential high value of diversification. We show the value at risk based measure is not coherent and this means it points out something different in this environment. It is can be an indicator of loss in opportunities for high end returns.

  19. Evaluation of Cyber Security and Modelling of Risk Propagation with Petri Nets

    Directory of Open Access Journals (Sweden)

    Marcin Szpyrka

    2017-02-01

    Full Text Available This article presents a new method of risk propagation among associated elements. On thebasis of coloured Petri nets, a new class called propagation nets is defined. This class providesa formal model of a risk propagation. The proposed method allows for model relations betweennodes forming the network structure. Additionally, it takes into account the bidirectional relationsbetween components as well as relations between isomorphic, symmetrical components in variousbranches of the network. This method is agnostic in terms of use in various systems and it canbe adapted to the propagation model of any systems’ characteristics; however, it is intentionallyproposed to assess the risk of critical infrastructures. In this paper, as a proof of concept example, weshow the formal model of risk propagation proposed within the project Cyberspace Security ThreatsEvaluation System of the Republic of Poland. In the article, the idea of the method is presented aswell as its use case for evaluation of risk for cyber threats. With the adaptation of Petri nets, it ispossible to evaluate the risk for the particular node and assess the impact of this risk for all relatednodes including hierarchic relations of components as well as isomorphism of elements.

  20. Psychosocial risks evaluation factors: study with higher education teachers

    Directory of Open Access Journals (Sweden)

    Sara Lopes Borges

    2018-02-01

    Method: The study consisted of the administration of two instruments, one for the characterization of the sample and the other for assessing psychosocial risk factors — the Copenhagen Psychosocial Questionnaire — consisting of 76 items (5-point Likert scale, distributed in five dimensions, which measure indicators of exposure to psychosocial risks and their effects. Results: The study included 59 teachers, mostly men (50.8%, aged between 41 - 50 years (45.8%, with master's degree (59%, assistant professors (47.5%; with a stable employment relationship (68%, years of service between 14-17 years (18.7% and teaching between 11 - 17 hours a week (64.4%. The analysis of the various subscales revealed a psychosocial risk, showing that teachers are in a situation of vulnerability. There were significant differences between the risks experienced in public higher education and those experienced in private higher education. Gender, age, academic background, and professional category influenced the type of psychosocial risk. Conclusions: The study confirms the importance of the evaluation of psychosocial risk factors in the exercise of the teaching profession in higher education. It is recognized that it is necessary to assess and manage psychosocial risks in order to promote healthy working conditions, ensure respect and fair treatment, and encourage the promotion of work / family life balance, in order to minimize psychosocial risks and situations of vulnerability in higher education teachers.

  1. Evaluation of risk management and financial performance of BMW Group

    OpenAIRE

    Mysina, Amira

    2017-01-01

    Effective risk and financial management possess a great challenge for the multinational companies operating globally. Despite the increasing development of diverse hedging strategies against foreign exchange risk, global firms cannot fully foresee and measure the degree of the impact of foreign currency fluctuations. This paper aims to evaluate the exchange risk management and financial performance of the BMW Group from the year 2005 to 2016. Moreover, this paper is devoted to provide explana...

  2. Risk informed inservice inspection evaluation of the ComEd nuclear plants

    International Nuclear Information System (INIS)

    Fleming, K.N.; Hutchinson, J.J.

    2000-01-01

    In November, 1999 Commonwealth Edison Company began the largest scope project yet performed to implement risk informed in-service inspection programs for piping systems. A contractor team led by ERIN Engineering and Research was selected to perform full scope risk informed evaluations on ten reactor units at five sites including 3 BWR and 2 PWR stations. This risk informed evaluation has applied a number of advancements to RISI technology in key areas including risk quantification of inspection program changes, element selection, treatment of multiple damage mechanisms at a given location, and in streamlining an approach to RISI initially developed by EPRI. The scope of the evaluation covered more than 18,000 ASME Class 1 and 2 welds not counting those that will continue to be inspected as part of augmented programs for flow accelerated corrosion, stress corrosion cracking, and service water systems. When the current ASME Section XI based exams are replaced by the risk informed program, while some new inspection locations will be added, substantial cost savings and person-rem exposures are projected from the elimination of most of the current exams. ComEd expects to recover its investment in the RISI evaluation for each of the 10 reactor units in 1 to 2 refueling outages, from the cost savings of reduced inspections. At the same time, the risk of a severe accident due to pipe ruptures is not expected to exhibit significant changes. (author)

  3. [Evaluation and prognosis of occupational risk in workers of nonferrous metallurgy enterprises].

    Science.gov (United States)

    Shliapnikov, D M; Kostarev, V G

    2014-01-01

    The article deals with results of a priori and a posteriori evaluation of occupational risk for workers' health. Categories of a priori occupational risk for workers are estimated as high to very high (intolerable) risk. Findings are that work conditions in nonferrous metallurgy workshop result in upper respiratory tract diseases (medium degree of occupational conditionality). Increased prevalence of such diseases among the workers is connected with length of service. The authors revealed priority factors for occupationally conditioned diseases. A promising approach in occupational medicine is creation of methods to evaluate and forecast occupational risk, that enable to specify goal parameters for prophylactic measures. For example, modelling the risk of occupationally conditioned diseases via changes in exposure to occupational factor and length of service proved that decrease of chemical concentrations in air of workplace to maximally allowable ones lowers risk of respiratory diseases from 14 to 6 cases per year, for length of service of 5 years and population risk.

  4. Gasbuggy Site Assessment and Risk Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-03-01

    The Gasbuggy site is in northern New Mexico in the San Juan Basin, Rio Arriba County (Figure 1-1). The Gasbuggy experiment was designed to evaluate the use of a nuclear detonation to enhance natural gas production from the Pictured Cliffs Formation, a tight, gas-bearing sandstone formation. The 29-kiloton-yield nuclear device was placed in a 17.5-inch wellbore at 4,240 feet (ft) below ground surface (bgs), approximately 40 ft below the Pictured Cliffs/Lewis shale contact, in an attempt to force the cavity/chimney formed by the detonation up into the Pictured Cliffs Sandstone. The test was conducted below the southwest quarter of Section 36, Township 29 North, Range 4 West, New Mexico Principal Meridian. The device was detonated on December 10, 1967, creating a 335-ft-high chimney above the detonation point and a cavity 160 ft in diameter. The gas produced from GB-ER (the emplacement and reentry well) during the post-detonation production tests was radioactive and diluted, primarily by carbon dioxide. After 2 years, the energy content of the gas had recovered to 80 percent of the value of gas in conventionally developed wells in the area. There is currently no technology capable of remediating deep underground nuclear detonation cavities and chimneys. Consequently, the U.S. Department of Energy (DOE) must continue to manage the Gasbuggy site to ensure that no inadvertent intrusion into the residual contamination occurs. DOE has complete control over the 1/4 section (160 acres) containing the shot cavity, and no drilling is permitted on that property. However, oil and gas leases are on the surrounding land. Therefore, the most likely route of intrusion and potential exposure would be through contaminated natural gas or contaminated water migrating into a producing natural gas well outside the immediate vicinity of ground zero. The purpose of this report is to describe the current site conditions and evaluate the potential health risks posed by the most plausible

  5. Evaluation of Risk Perception and Risk-Comparison Information Regarding Dietary Radionuclides after the 2011 Fukushima Nuclear Power Plant Accident

    Science.gov (United States)

    Murakami, Michio; Nakatani, Jun; Oki, Taikan

    2016-01-01

    In the wake of the 2011 Fukushima Daiichi Nuclear Power Station accident, to facilitate evidence-based risk communication we need to understand radiation risk perception and the effectiveness of risk-comparison information. We measured and characterized perceptions of dread risks and unknown risks regarding dietary radionuclides in residents of Fukushima, Tokyo, and Osaka to identify the primary factors among location, evacuation experience, gender, age, employment status, absence/presence of spouse, children and grandchildren, educational background, humanities/science courses, smoking habits, and various types of trustworthy information sources. We then evaluated the effects of these factors and risk-comparison information on multiple outcomes, including subjective and objective understanding, perceived magnitude of risk, perceived accuracy of information, backlash against information, and risk acceptance. We also assessed how risk-comparison information affected these multiple outcomes for people with high risk perception. Online questionnaires were completed by people (n = 9249) aged from 20 to 69 years in the three prefectures approximately 5 years after the accident. We gave each participant one of 15 combinations of numerical risk data and risk-comparison information, including information on standards, smoking-associated risk, and cancer risk, in accordance with Covello’s guidelines. Dread-risk perception among Fukushima residents with no experience of evacuation was much lower than that in Osaka residents, whereas evacuees had strikingly higher dread-risk perception, irrespective of whether their evacuation had been compulsory or voluntary. We identified location (distance from the nuclear power station), evacuation experience, and trust of central government as primary factors. Location (including evacuation experience) and trust of central government were significantly associated with the multiple outcomes above. Only information on “cancer risk from

  6. Benefit-risk evaluation of mammographic mass screening

    International Nuclear Information System (INIS)

    Sato, Nobuo; Ogura, Toshihiro

    1990-01-01

    This study evaluated the benefit-risk balance of mammography in mass screening by using survival rates from 3000 breast cancer patients at the Japanese Foundation for Cancer Research Institute Hospital. Because the number of participants in mammographic mass screening was small, asymptomatic patients with pathologically proven early breast cancer were categorized as the screenee group. Symptomatic patients were categorized as the patient group. Survival rates were compared in both the screenee and the patient groups. Based on the difference in areas of survival curves between screenees and patients, the ratio of person-year gain (PYG) to person-year lost (PYL) was obtained. The ratio of PYG to PYL was multiplied by the detection rate resulting from a particular screening program to obtain the benefit/risk ratio. The detection rate of nonpalpable breast cancer was 15 times higher in the screenee group than the patient group. Breast cancer was detected in 7 (0.85%) of 824 patients in the screenee group. Even when mammographic mass screening was started at the age of 30, the benefit of mammography was far superior to the risk. The number of participants in mass screening stratified by age may be required for the conclusion of the benefit-risk balance of mammography in mass screening. (N.K.)

  7. Obesity, physical activity and cancer risks: Results from the Cancer, Lifestyle and Evaluation of Risk Study (CLEAR).

    Science.gov (United States)

    Nunez, Carlos; Bauman, Adrian; Egger, Sam; Sitas, Freddy; Nair-Shalliker, Visalini

    2017-04-01

    Physical activity (PA) has been associated with lower risk of cardiovascular diseases, but the evidence linking PA with lower cancer risk is inconclusive. We examined the independent and interactive effects of PA and obesity using body mass index (BMI) as a proxy for obesity, on the risk of developing prostate (PC), postmenopausal breast (BC), colorectal (CRC), ovarian (OC) and uterine (UC) cancers. We estimated odds ratios (OR) and 95% confidence intervals (CI), adjusting for cancer specific confounders, in 6831 self-reported cancer cases and 1992 self-reported cancer-free controls from the Cancer Lifestyle and Evaluation of Risk Study, using unconditional logistic regression. For women, BMI was positively associated with UC risk; specifically, obese women (BMI≥30kg/m 2 ) had nearly twice the risk of developing UC compared to women with healthy-BMI-range (risk of developing any cancer type, CRC and PC. In particular, obese men had 37% (OR=1.37;CI:1.11-1.70), 113% (OR=2.13;CI:1.55-2.91) and 51% (OR=1.51;CI:1.17-1.94) higher risks of developing any cancer, CRC and PC respectively, when compared to men with healthy-BMI-range (BMIrisks of CRC, UC and BC. In particular, the highest level of PA (versus nil activity) was associated with reduced risks of CRC (OR=0.60;CI:0.44-0.84) and UC (OR=0.47;CI:0.27-0.80). Reduced risks of BC were associated with low (OR=0.66;CI:0.51-0.86) and moderate (OR=0.72;CI:0.57-0.91) levels of PA. There was no association between PA levels and cancer risks for men. We found no evidence of an interaction between BMI and PA in the CLEAR study. These findings suggest that PA and obesity are independent cancer risk factors. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Non-animal approaches for toxicokinetics in risk evaluations of food chemicals.

    Science.gov (United States)

    Punt, Ans; Peijnenburg, Ad A C M; Hoogenboom, Ron L A P; Bouwmeester, Hans

    2017-01-01

    The objective of the present work was to review the availability and predictive value of non-animal toxicokinetic approaches and to evaluate their current use in European risk evaluations of food contaminants, additives and food contact materials, as well as pesticides and medicines. Results revealed little use of quantitative animal or human kinetic data in risk evaluations of food chemicals, compared with pesticides and medicines. Risk evaluations of medicines provided sufficient in vivo kinetic data from different species to evaluate the predictive value of animal kinetic data for humans. These data showed a relatively poor correlation between the in vivo bioavailability in rats and dogs versus that in humans. In contrast, in vitro (human) kinetic data have been demonstrated to provide adequate predictions of the fate of compounds in humans, using appropriate in vitro-in vivo scalers and by integration of in vitro kinetic data with in silico kinetic modelling. Even though in vitro kinetic data were found to be occasionally included within risk evaluations of food chemicals, particularly results from Caco-2 absorption experiments and in vitro data on gut-microbial conversions, only minor use of in vitro methods for metabolism and quantitative in vitro-in vivo extrapolation methods was identified. Yet, such quantitative predictions are essential in the development of alternatives to animal testing as well as to increase human relevance of toxicological risk evaluations. Future research should aim at further improving and validating quantitative alternative methods for kinetics, thereby increasing regulatory acceptance of non-animal kinetic data.

  9. The Comprehensive Evaluation Method of Supervision Risk in Electricity Transaction Based on Unascertained Rational Number

    Science.gov (United States)

    Haining, Wang; Lei, Wang; Qian, Zhang; Zongqiang, Zheng; Hongyu, Zhou; Chuncheng, Gao

    2018-03-01

    For the uncertain problems in the comprehensive evaluation of supervision risk in electricity transaction, this paper uses the unidentified rational numbers to evaluation the supervision risk, to obtain the possible result and corresponding credibility of evaluation and realize the quantification of risk indexes. The model can draw the risk degree of various indexes, which makes it easier for the electricity transaction supervisors to identify the transaction risk and determine the risk level, assisting the decision-making and realizing the effective supervision of the risk. The results of the case analysis verify the effectiveness of the model.

  10. Risk from environmental chemicals

    Energy Technology Data Exchange (ETDEWEB)

    Somers, E [Environmental Health Directorate, Health Protection Branch, Health and Welfare Canada, Ontario

    1982-01-01

    The elements of risk assessment, namely risk identification, risk estimation, risk evaluation and risk management, are described with respect to the control of environmental chemicals. The methodology of risk estimation is outlined and examples given of its application to regulatory decision-making for a number of chemicals in Canada. Finally, the extent and limitations of the process of risk evaluation are considered together with the need to recognize the importance of the public's perception of the level of risk.

  11. Evaluation of risk of atherosclerosis in Indian adults.

    Science.gov (United States)

    Pandit, Deepa; Chiplonkar, Shashi; Khadilkar, Anuradha; Kinare, Arun; Khadilkar, Vaman; Divate, Uma

    2013-05-01

    To investigate interrelationship of arterial measurements with metabolic syndrome (MS) components and zinc status in apparently healthy Indian adults. Anthropometry and biochemical data were recorded in 110 men and 139 women (25-50 yr). Carotid Intima media thickness (CIMT), stiffness (beta), pulse wave velocity (PWV), elasticity modulus (Ep), and arterial compliance (AC) of the right carotid artery were evaluated ultrasonically. According to definition of MS, subjects were categorized as MS-1, MS-2, MS-3. Further, normal and MS subjects were divided as zinc sufficient and deficient. In all, 12.1% subjects had 3 risk factors for MS. Mean CIMT, beta, Ep and PWV were significantly higher by 6%, 11.6%, 29.5% and 12.4% in subjects with MS than normal (p < 0.05). AC showed significant decline in MS subjects by only 3% than normal (p < 0.05). Serum zinc was inversely correlated with beta, Ep and PWV in both the genders in subjects with MS (p < 0.05). A synergistic effect of serum zinc deficiency with MS further envisages the elevated risk of arterial stiffness. Risk of atherosclerosis is marked by increase in stiffness parameters even in presence of a single MS risk and zinc deficiency may further aggravate the risk indicating need for early diagnosis.

  12. Risk indicators as a tool for risk control

    International Nuclear Information System (INIS)

    Oien, K.

    2001-01-01

    This paper presents a general methodology for the establishment of risk indicators that can be used as a tool for risk control during operation of offshore petroleum installations. The risk indicators established are based on the platform specific quantitative risk analysis (QRA). The general methodology is evaluated against comparable approaches both in offshore and nuclear industry. There are two distinct features of this methodology. The first is that it is truly risk-based with the intention of covering the total risk picture. The second is that the identification of the risk factors contributing most to the total risk is based on realistic changes of each factor assessed by the platform personnel, not a theoretically assumed change. The set of risk indicators for one specific installation is presented along with test results

  13. Assaying the effect of levodopa on the evaluation of risk in healthy humans.

    Directory of Open Access Journals (Sweden)

    Mkael Symmonds

    Full Text Available In humans, dopamine is implicated in reward and risk-based decision-making. However, the specific effects of dopamine augmentation on risk evaluation are unclear. Here we sought to measure the effect of 100 mg oral levodopa, which enhances synaptic release of dopamine, on choice behaviour in healthy humans. We use a paradigm without feedback or learning, which solely isolates effects on risk evaluation. We present two studies (n = 20; n = 20 employing a randomised, placebo-controlled, within-subjects design. We manipulated different dimensions of risk in a controlled economic paradigm. We test effects on risk-reward tradeoffs, assaying both aversion to variance (the spread of possible outcomes and preference for relative losses and gains (asymmetry of outcomes--skewness, dissociating this from potential non-specific effects on choice randomness using behavioural modelling. There were no systematic effects of levodopa on risk attitudes, either for variance or skewness. However, there was a drift towards more risk-averse behaviour over time, indicating that this paradigm was sensitive to detect changes in risk-preferences. These findings suggest that levodopa administration does not change the evaluation of risk. One possible reason is that dopaminergic influences on decision making may be due to changing the response to reward feedback.

  14. Risk evaluation and mitigation strategies: a focus on the mycophenolic acid preparations.

    Science.gov (United States)

    Rostas, Sara; Kim, Miae; Gabardi, Steven

    2014-03-01

    To review risks associated with mycophenolic acid (MPA) preparations and evaluate their required risk evaluation and mitigation strategies (REMS) elements. Articles were identified through a non-date-limited MEDLINE and EMBASE search using the terms fetal toxicity, teratogenicity, risk evaluation and mitigation strategies, REMS, MPA, mycophenolate mofetil, entericcoated MPA, and organ transplant. Information from the Food and Drug Administration (FDA) and the manufacturers of the MPA preparations was also evaluated. The MPA preparations are associated with several potential risks, including gastrointestinal disturbances and myelosuppression; however, their impact on the fetus in pregnant patients taking 1 of these agents poses the greatest risk. The FDA approved REMS programs for all MPA products, both innovator and generic preparations, in September 2012. With evidence of increased risk of miscarriage and birth defects associated with MPA use, the FDA instituted a REMS program that contains both a medication guide and elements to assure safe use (ETASU). The medication guides for the MPA products, which were previously FDA approved, should continue to be distributed to patients who get either an initial prescription filled or a refill. The ETASU requires prescribers to complete training and obtain patient signatures on the Patient-Prescriber Acknowledgment Form. A single, national, voluntary pregnancy registry specific to this medication has been established, and pregnant patients should be encouraged to participate. Although the impact of the MPA REMS on clinical practice is not clear, it is a step toward increasing the understanding of fetal risks with MPA.

  15. Evaluating the risk-reduction benefits of wind energy

    Energy Technology Data Exchange (ETDEWEB)

    Brower, M.C. [Brower & Company, Andover, MA (United States); Bell, K. [Convergence Research, Seattle, WA (United States); Bernow, S.; Duckworth, M. [Tellus Inst., Boston, MA (United States); Spinney P. [Charles River Associates, Boston, MA (United States)

    1996-12-31

    This paper presents preliminary results of a study to evaluate the risk-reduction benefits of wind power for a case study utility system using decision analysis techniques. The costs and risks of two alternative decisions-whether to build a 400 MW gas-fired combined cycle plant or a 1600 MW wind plant in 2003-were compared through computer simulations as fuel prices, environmental regulatory costs, wind and conventional power plant availability, and load growth were allowed to vary. Three different market scenarios were examined: traditional regulation, a short-term power pool, and fixed-price contracts of varying duration. The study concludes that, from the perspective of ratepayers, wind energy provides a net levelized risk-reduction benefit of $3.4 to $7.8/MWh under traditional regulation, and less in the other scenarios. From the perspective of the utility plant owners, wind provides a significant risk benefit in the unregulated market scenarios but none in a regulated market. The methodology and findings should help inform utility resource planning and industry restructuring efforts. 2 figs., 3 tabs.

  16. Risk evaluation on leading companies in property and real estate subsector at IDX: A Value-at-Risk with ARMAX-GARCHX approach and duration test

    Science.gov (United States)

    Dwi Prastyo, Dedy; Handayani, Dwi; Fam, Soo-Fen; Puteri Rahayu, Santi; Suhartono; Luh Putu Satyaning Pradnya Paramita, Ni

    2018-03-01

    Risk assessment and evaluation becomes essential for financial institution to measure the potential risk of their counterparties. In middle of 2016 until first quarter of 2017, there is national program from Indonesian government so-called Tax Amnesty. One subsector that has potential to receive positive impact from the Tax Amnesty program is property and real estate. This work evaluates the risk of top five companies in term of capital share listed in Indonesia stock exchange (IDX). To do this, the Value-at-Risk (VaR) with ARMAX-GARCHX approach is employed. The ARMAX-GARCHX simultaneously models the adaptive mean and variance of stock return of each company considering exogenous variables, i.e. IDR/USD exchange rate and Jakarta Composite Index (JCI). The risk is evaluated in scheme of time moving window. The risk evaluation using 5% quantile with window size 500 transaction days perform better result compare to other scenarios. In addition, duration test is used to test the dependency between shortfalls. It informs that series of shortfall are independent.

  17. Hazard evaluation and risk management

    International Nuclear Information System (INIS)

    Fritzsche, A.F.

    1986-01-01

    The eigth chapter deals with the actual handling of hazards. The principal issue concerns man's behaviour towards hazards as an individual formerly and today; the evaluation of expected results of both a positive and a negative kind as determined by the individual's values which may differ and vary greatly from one individual to the next. The evaluation of benefit and hazard as well as the risk management resulting from decision-taking are political processes in the democratic state. Formal decision-taking tools play a major role in this process which concerns such central issues like who will participate; how the decision is arrived at; the participation of citizens; specialist knowledge and participation of the general public. (HSCH) [de

  18. Risk Analysis Based on AHP and Fuzzy Comprehensive Evaluation for Maglev Train Bogie

    Directory of Open Access Journals (Sweden)

    Chengxin Fan

    2016-01-01

    Full Text Available The maglev bogie is the key subsystem for maglev train security. To ensure life and property security, it is essential to evaluate its risk level before its operation. In this paper, a combinational method of analytic hierarchy process and fuzzy comprehensive evaluation is proposed to assess hazards in a complex maglev bogie system associated with multiple subsystems’ failures. The very comprehensive identification of risk sources has been done by analyzing the structure of maglev bogie. Furthermore, based on the fuzzy theory, linguistic evaluation set is classified according to risk tolerance. The score of each risk factor is obtained by weighted sum of the result of fuzzy comprehensive evaluation. Our results show that the degree of maglev bogie’s risk is within the range of acceptability. The merits of this work facilitate finding the weak links and determining the maintenance of maglev bogie system.

  19. Credit Risk Evaluation of Large Power Consumers Considering Power Market Transaction

    Science.gov (United States)

    Fulin, Li; Erfeng, Xu; ke, Sun; Dunnan, Liu; Shuyi, Shen

    2018-03-01

    Large power users will participate in power market in various forms after power system reform. Meanwhile, great importance has always attached to the construction of the credit system in power industry. Due to the difference between the awareness of performance and the ability to perform, credit risk of power customer will emerge accordingly. Therefore, it is critical to evaluate credit risk of large power customers in the new situation of power market. Firstly, this paper constructs index system of credit risk of large power customers, and establishes evaluation model of interval number and AHP-entropy weight method.

  20. Overcoming Learning Aversion in Evaluating and Managing Uncertain Risks.

    Science.gov (United States)

    Cox, Louis Anthony Tony

    2015-10-01

    Decision biases can distort cost-benefit evaluations of uncertain risks, leading to risk management policy decisions with predictably high retrospective regret. We argue that well-documented decision biases encourage learning aversion, or predictably suboptimal learning and premature decision making in the face of high uncertainty about the costs, risks, and benefits of proposed changes. Biases such as narrow framing, overconfidence, confirmation bias, optimism bias, ambiguity aversion, and hyperbolic discounting of the immediate costs and delayed benefits of learning, contribute to deficient individual and group learning, avoidance of information seeking, underestimation of the value of further information, and hence needlessly inaccurate risk-cost-benefit estimates and suboptimal risk management decisions. In practice, such biases can create predictable regret in selection of potential risk-reducing regulations. Low-regret learning strategies based on computational reinforcement learning models can potentially overcome some of these suboptimal decision processes by replacing aversion to uncertain probabilities with actions calculated to balance exploration (deliberate experimentation and uncertainty reduction) and exploitation (taking actions to maximize the sum of expected immediate reward, expected discounted future reward, and value of information). We discuss the proposed framework for understanding and overcoming learning aversion and for implementing low-regret learning strategies using regulation of air pollutants with uncertain health effects as an example. © 2015 Society for Risk Analysis.

  1. Technology Evaluation for Environmental Risk Mitigation Compendium

    Science.gov (United States)

    Meinhold, A.; Greene, B.; Dussich, J.; Sorkin, A.; Olsen, W.

    2017-01-01

    The Technology Evaluation for Environmental Risk Mitigation (TEERM) Principal Center and its predecessor organization the Acquisition Pollution Prevention Program (AP2) supported the National Aeronautics and Space Administration (NASA) in identifying technology solutions to risks and costs to NASA programs driven by environmental regulations and requirements. TEERM researched the commercial and government marketplace to locate viable and available technologies that met NASAs needs. TEERM focused on addressing environmentally-driven risks of direct concern to NASA programs and facilities, including hazardous materials in NASA operations and materials that became obsolescent because of environmental regulations. TEERM projects aimed to reduce cost; ensure the health and safety of people, assets, and the environment; promote efficiency; and minimize duplication. Major TEERM and AP2 projects focused on waste minimization and hazardous waste treatment, recycling, corrosion prevention and control, solvent and ozone depleting substances substitution, and aqueous based cleaners. In 2017, NASA made the decision to terminate the TEERM Principal Center. This Compendium Report documents TEERM and AP2 project successes. The Compendium Report traces the evolution of TEERM based on evolving risks and requirements for NASA and its relationship to the Space Shuttle Program, the United States Department of Defense, the European Space Agency, and other public and private stakeholders. This Compendium Report also documents project details from Project Summaries and Joint Test Plans and describes project stakeholders and collaborative effort results.

  2. Municipal Treated Wastewater Irrigation: Microbiological Risk Evaluation

    Directory of Open Access Journals (Sweden)

    Antonio Lonigro

    2008-06-01

    Full Text Available Municipal wastewater for irrigation, though treated, can contain substances and pathogens toxic for humans and animals. Pathogens, although not harmful from an agronomical aspect, undoubtedly represent a major concern with regards to sanitary and hygienic profile. In fact, vegetable crops irrigated with treated wastewater exalt the risk of infection since these products can also be eaten raw, as well as transformed or cooked. Practically, the evaluation of the microbiological risk is important to verify if the microbial limits imposed by law for treated municipal wastewater for irrigation, are valid, thus justifying the treatments costs, or if they are too low and, therefore, they don’ t justify them. Different probabilistic models have been studied to assess the microbiological risk; among these, the Beta-Poisson model resulted the most reliable. Thus, the Dipartimento di Scienze delle Produzioni Vegetali of the University of Bari, which has been carrying out researches on irrigation with municipal filtered wastewater for several years, considered interesting to verify if the microbial limits imposed by the italian law n.185/03 are too severe, estimating the biological risk by the probabilistic Beta-Poisson model. Results of field trials on vegetable crops irrigated by municipal filtered wastewater, processed by the Beta-Poisson model, show that the probability to get infection and/or illness is extremely low, and that the actual italian microbial limits are excessively restrictive.

  3. Applied decision analysis and risk evaluation

    International Nuclear Information System (INIS)

    Ferse, W.; Kruber, S.

    1995-01-01

    During 1994 the workgroup 'Applied Decision Analysis and Risk Evaluation; continued the work on the knowledge based decision support system XUMA-GEFA for the evaluation of the hazard potential of contaminated sites. Additionally a new research direction was started which aims at the support of a later stage of the treatment of contaminated sites: The clean-up decision. For the support of decisions arising at this stage, the methods of decision analysis will be used. Computational aids for evaluation and decision support were implemented and a case study at a waste disposal site in Saxony which turns out to be a danger for the surrounding groundwater ressource was initiated. (orig.)

  4. Evaluation of Postural Stability and Fall Risk in Patients with Ankylosing Spondylitis

    Directory of Open Access Journals (Sweden)

    Ahmet Inanir

    2013-02-01

    Full Text Available Purpose: The purpose of this study is to evaluate the influences of Ankylosing spondylitis on postural balance and the risk of falls. Methods: A total of 73 sobjects were recruited for the study, including 36 with AS (17 men, 19 women and 37 healthy controls (19 men, 18 women. Patients were evaluated in terms of balance and risk of falls. Balance and risk of falls was assessed with the Biodex Stability System. Results: The mean age, gender and body mass index of the participants did not differ significantly between (p=0.308, p=0.724, p=0.766, respectively. When groups were evaluated in terms of postural stability indexes Overall Stability Index (OSI, Antero-Posteior Stability Index (APSI and Medio-Lateral Stability Index (MLSI had no statistically significant difference (p=0.190, p=0.437 ve p=0.144, respectively. Fall Risk Index (FRI evaluations showed that as patients’ test scores were higher than control group (p=0.001. (Table 1. Conclusions: In this study, we present numerical data that suggests that AS are associated with risk of falling. [Cukurova Med J 2013; 38(1.000: 86-91

  5. A European Commission software tool for radon risk calculation and evaluation of countermeasures

    Energy Technology Data Exchange (ETDEWEB)

    Degrange, J.P.; Levy, F.P. [CEPN, Fontenay-aux-Roses Cedex (France); Birchall, A.; Haylock, R.; Marsh, J.; Muirhead, C. [National Radiological Protection Board, Chilton (United Kingdom); Janssens, A. [European Commission, DG XI (Luxembourg)

    2000-05-01

    The effects of exposure to radon on workers and members of the public have been examined for many years. Recent advances have been made in evaluating the risk associated with radon exposure and in implementing remediation programmes in dwellings. However, decisions about whether to implement countermeasures to reduce radon exposures may benefit from an enhanced capability to evaluate and understand the associated health risk. In this context, the European Commission has launched a project to develop a user friendly software package based upon current information on radon epidemiology, radon dosimetry, demography, and countermeasure efficiency. The software has been designed to perform lung cancer risk calculations specific to European populations for various exposure profiles and to evaluate, in terms of risk reduction, the efficiency of various countermeasures in dwellings. This paper presents an overview of the general structure of the software and outlines its most important modelling approaches. The software is able to evaluate the risk of fatal lung cancer associated with individual or collective exposure to radon. The individual risk calculation module determines, for an individual of given age, sex and tobacco consumption, the excess risk for a given exposure (past or future exposure) time-profile, on the basis of demographic data (WHO, 1996 and 1998) specific to the selected population. The collective risk calculation module determines the excess risk for each occupant of a dwelling, for an exposure time-profile derived from data describing the dwelling, its occupancy, and the chosen countermeasures. These calculations may be done using one of two classical approaches: 1) The epidemiological approach in which the risk is obtained directly from the radon exposure data using a risk model (BEIR IV, 1988; BEIR VI, 1999) derived from epidemiological studies of uranium miners; 2) The dosimetric approach in which the risk is derived from the radon exposure data

  6. A European Commission software tool for radon risk calculation and evaluation of countermeasures

    International Nuclear Information System (INIS)

    Degrange, J.P.; Levy, F.P.; Birchall, A.; Haylock, R.; Marsh, J.; Muirhead, C.; Janssens, A.

    2000-01-01

    The effects of exposure to radon on workers and members of the public have been examined for many years. Recent advances have been made in evaluating the risk associated with radon exposure and in implementing remediation programmes in dwellings. However, decisions about whether to implement countermeasures to reduce radon exposures may benefit from an enhanced capability to evaluate and understand the associated health risk. In this context, the European Commission has launched a project to develop a user friendly software package based upon current information on radon epidemiology, radon dosimetry, demography, and countermeasure efficiency. The software has been designed to perform lung cancer risk calculations specific to European populations for various exposure profiles and to evaluate, in terms of risk reduction, the efficiency of various countermeasures in dwellings. This paper presents an overview of the general structure of the software and outlines its most important modelling approaches. The software is able to evaluate the risk of fatal lung cancer associated with individual or collective exposure to radon. The individual risk calculation module determines, for an individual of given age, sex and tobacco consumption, the excess risk for a given exposure (past or future exposure) time-profile, on the basis of demographic data (WHO, 1996 and 1998) specific to the selected population. The collective risk calculation module determines the excess risk for each occupant of a dwelling, for an exposure time-profile derived from data describing the dwelling, its occupancy, and the chosen countermeasures. These calculations may be done using one of two classical approaches: 1) The epidemiological approach in which the risk is obtained directly from the radon exposure data using a risk model (BEIR IV, 1988; BEIR VI, 1999) derived from epidemiological studies of uranium miners; 2) The dosimetric approach in which the risk is derived from the radon exposure data

  7. Assessment of Risk Evaluation and Mitigation Strategies in Oncology: Summary of the Oncology Risk Evaluation and Mitigation Strategies Workshop

    Science.gov (United States)

    Frame, James N.; Jacobson, Joseph O.; Vogel, Wendy H.; Griffith, Niesha; Wariabharaj, Darshan; Garg, Rekha; Zon, Robin; Stephens, Cyntha L.; Bialecki, Alison M.; Bruinooge, Suanna S.; Allen, Steven L.

    2013-01-01

    To address oncology community stakeholder concerns regarding implementation of the Risk Evaluation and Mitigation Strategies (REMS) program, ASCO sponsored a workshop to gather REMS experiences from representatives of professional societies, patient organizations, pharmaceutical companies, and the US Food and Drug Administration (FDA). Stakeholder presentations and topical panel discussions addressed REMS program development, implementation processes, and practice experiences, as well as oncology drug safety processes. A draft REMS decision tool prepared by the ASCO REMS Steering Committee was presented for group discussion with facilitated, goal-oriented feedback. The workshop identified several unintended consequences resulting from current oncology REMS: (1) the release of personal health information to drug sponsors as a condition for gaining access to a needed drug; (2) risk information that is not tailored—and therefore not accessible—to all literacy levels; (3) exclusive focus on drug risk, thereby affecting patient-provider treatment discussion; (4) REMS elements that do not consider existing, widely practiced oncology safety standards, professional training, and experience; and (5) administrative burdens that divert the health care team from direct patient care activities and, in some cases, could limit patient access to important therapies. Increased provider and professional society participation should form the basis of ongoing and future REMS standardization discussions with the FDA to work toward overall improvement of risk communication. PMID:23814522

  8. Toward a risk assessment of the spent fuel and high-level nuclear waste disposal system. Risk assessment requirements, literature review, methods evaluation: an interim report

    Energy Technology Data Exchange (ETDEWEB)

    Hamilton, L.D.; Hill, D.; Rowe, M.D.; Stern, E.

    1986-04-01

    This report provides background information for a risk assessment of the disposal system for spent nuclear fuel and high-level radioactive waste (HLW). It contains a literature review, a survey of the statutory requirements for risk assessment, and a preliminary evaluation of methods. The literature review outlines the state of knowledge of risk assessment and accident consequence analysis in the nuclear fuel cycle and its applicability to spent fuel and HLW disposal. The survey of statutory requirements determines the extent to which risk assessment may be needed in development of the waste-disposal system. The evaluation of methods reviews and evaluates merits and applicabilities of alternative methods for assessing risks and relates them to the problems of spent fuel and HLW disposal. 99 refs.

  9. Toward a risk assessment of the spent fuel and high-level nuclear waste disposal system. Risk assessment requirements, literature review, methods evaluation: an interim report

    International Nuclear Information System (INIS)

    Hamilton, L.D.; Hill, D.; Rowe, M.D.; Stern, E.

    1986-04-01

    This report provides background information for a risk assessment of the disposal system for spent nuclear fuel and high-level radioactive waste (HLW). It contains a literature review, a survey of the statutory requirements for risk assessment, and a preliminary evaluation of methods. The literature review outlines the state of knowledge of risk assessment and accident consequence analysis in the nuclear fuel cycle and its applicability to spent fuel and HLW disposal. The survey of statutory requirements determines the extent to which risk assessment may be needed in development of the waste-disposal system. The evaluation of methods reviews and evaluates merits and applicabilities of alternative methods for assessing risks and relates them to the problems of spent fuel and HLW disposal. 99 refs

  10. Evaluation of consequences and risks in Slovenia

    International Nuclear Information System (INIS)

    Susnik, J.

    1996-01-01

    The paper describes the evaluation of nuclear power plant accident consequences and risks using probabilistic safety codes during the last 12 years at the J. Stefan Institute. They cover classic individual and population risk studies due to assumed potential severe accident scenarios, prediction and estimation of Chernobyl accident consequences, the optimization of emergency countermeasures at the Krsko site, where the 632 MWe Westinghouse PWR NPP went into commercial operation on January 1983, and the ranking of population risk within the public debate in connection with the civil initiative to close the NPP Krsko. We report on the initial use of the CRAC2 code in 1984 and later, when it was first applied for the study of population risk in the area of the second planned Slovenian-Croatian NPP for the Prevlaka site. The study was completed a few weeks before the Chernobyl accident in April 1986. Risk evaluation was also included in the analysis of nuclear safety at the NPP Krsko during the war for Slovenia's independence in 1991. We report on the (CRAC2) analyses of the Chernobyl accident: on initial estimation of the maximal potentially expected consequences in Slovenia, on the effect of the radioactive cloud rise on the consequences relatively close to the NPP; on the further research after the detailed information on the radioactivity release and on the air masses movement were published; then the cloud activity which moved towards Slovenia was assessed and the expected consequences along its path were calculated. As the calculated integral individual exposure to the I 131 inhalation and the ground Cs 137 contamination matched with the measurements in Ljubljana and with the UNSCEAR 1988 data, our reliance on the CRAC2 code and on its ancestors is high. We report on the analyses, performed by the CRAC2 code and since 1993 also by the PC COSYMA code, related to the countermeasure effects. The consequences studied were extended to late health effects. We analyzed

  11. Evaluation of severe accident risks and the potential for risk reduction: Surry Power Station, Unit 1: Draft report for comment

    International Nuclear Information System (INIS)

    Benjamin, A.S.; Boyd, G.J.; Kunsman, D.M.; Murfin, W.B.; Williams, D.C.

    1987-02-01

    The Severe Accident Risk Reduction Program (SARRP) has completed a rebaselining of the risks to the public from a particular pressurized water reactor with a subatmospheric containment (Surry, Unit 1). Emphasis was placed on determining the magnitude and character of the uncertainties, rather than focusing on a point estimate. The risk-reduction potential of a set of proposed safety option backfits was also studied, and their costs and benefits were also evaluated. It was found that the risks from internal events are generally lower than previously evaluated in the Reactor Safety Study (RSS). However, certain unresolved issues (such as direct containment heating) caused the top of the uncertainty band to appear at a level that is comparable with the RSS point estimate. None of the postulated safety options appears to be cost effective for the Surry power plant. This work supports the Nuclear Regulatory Commission's assessment of severe accidents in NUREG-1150

  12. Evaluation of severe accident risks and the potential for risk reduction: Surry Power Station, Unit 1: Draft report for comment

    Energy Technology Data Exchange (ETDEWEB)

    Benjamin, A.S.; Boyd, G.J.; Kunsman, D.M.; Murfin, W.B.; Williams, D.C.

    1987-02-01

    The Severe Accident Risk Reduction Program (SARRP) has completed a rebaselining of the risks to the public from a particular pressurized water reactor with a subatmospheric containment (Surry, Unit 1). Emphasis was placed on determining the magnitude and character of the uncertainties, rather than focusing on a point estimate. The risk-reduction potential of a set of proposed safety option backfits was also studied, and their costs and benefits were also evaluated. It was found that the risks from internal events are generally lower than previously evaluated in the Reactor Safety Study (RSS). However, certain unresolved issues (such as direct containment heating) caused the top of the uncertainty band to appear at a level that is comparable with the RSS point estimate. None of the postulated safety options appears to be cost effective for the Surry power plant. This work supports the Nuclear Regulatory Commission's assessment of severe accidents in NUREG-1150.

  13. Mammary radiotherapy and patients-risks management with continue evaluation of clinical indicators

    International Nuclear Information System (INIS)

    Untereiner, M.; Frederick, B.; Burie, D.; Cavuto, C.; Rob, L.; Coiffier, N.; Colet, M.

    2009-01-01

    Purpose: The breast irradiation represents 25% of radiotherapy indication in the radiotherapy centers. The modeling of the management of complications risks and recurrences in relation with mammary irradiation constitutes a methodological base allowing to develop a general concept for any other indication of radiotherapy. The objective of the study was a continuous evaluation of clinical risks to get indicators of the therapy results: for the institution, to get an auto-evaluation tool of the functioning (continuous evaluation of clinical results, identification of sentinel events); for the patients to get precise and detailed information on the risks linked to their treatment (communication of clinical results, comparison with the literature, benchmarking). (N.C.)

  14. A Method for Evaluating Competency in Assessment and Management of Suicide Risk

    Science.gov (United States)

    Hung, Erick K.; Binder, Renee L.; Fordwood, Samantha R.; Hall, Stephen E.; Cramer, Robert J.; McNiel, Dale E.

    2012-01-01

    Objective: Although health professionals increasingly are expected to be able to assess and manage patients' risk for suicide, few methods are available to evaluate this competency. This report describes development of a competency-assessment instrument for suicide risk-assessment (CAI-S), and evaluates its use in an objective structured clinical…

  15. Project finance risk evaluation of the Electric power industry of Serbia

    International Nuclear Information System (INIS)

    Makajic Nikolic, Dragana; Jednak, Sandra; Benkovic, Sladana; Poznanic, Vladimir

    2011-01-01

    From the aspect of the development of a country, the energy sector represents a domain of strategic interest. Generation and use of energy resources most often belongs to the public sector, and are most often under the influence of the government in most countries. This paper analyzes the risks that are characteristic to the business of the public enterprise, Electric Power Industry of Serbia (EPS). EPS has started its restructuring and is adjusting to changes and challenges imposed by the launched reforms in the energy sector. However, due to certain limitations, it is still not possible to implement its complete restructuring and modernization. The paper aims to point at the risks a potential strategic partner faces. The risks have been identified as commercial, financial and political, classification immanent for project finance, and their evaluation was done using Failure Mode and Effects Analysis (FMEA). Risk analysis was performed based on current conditions for two potential scenarios that predict different types of changes in the analyzed period. The results of the analysis show that the potential strategic partner should pay special attention to price risks, estimation, investments, project activity neglect, quasi-risks and debt collection. - Highlights: → Paper analyze all risks characteristic for business running of the public enterprise EPS. → Potential strategic partner faces with the commercial, financial and political risks. → Risk analysis was done using FMEA. → Results are indicating high risk of investing in EPS. → The highest risks are commercial risks, especially price risks.

  16. Regional Risk Evaluation of Flood Disasters for the Trunk-Highway in Shaanxi, China

    Directory of Open Access Journals (Sweden)

    Hong-Liang Qi

    2015-10-01

    Full Text Available Due to the complicated environment there are various types of highway disasters in Shaanxi Province (China. The damages caused are severe, losses are heavy, and have rapidly increased over the years, especially those caused by flood disasters along the rivers in mountainous areas. Therefore, research on risk evaluations, which play important roles in the prevention and mitigation of highway disasters are very important. An evaluation model was established based on the superposition theory of regional influencing factors to highway flood disasters. Based on the formation mechanism and influencing factors of highway flood disasters, the main influencing factors were selected. These factors include rainstorms, terrain slopes, soil types, vegetation coverage and regional river density, which are based on evaluation indexes from climate conditions and underlying surface of the basin. A regional risk evaluation of highway flood disasters in Shaanxi was established using GIS. The risk index was divided into five levels using statistical methods, in accordance with the regional characteristics of highway flood disasters. Considering the difference in upfront investments, road grade, etc, between expressways and trunk-highways in China, a regional risk evaluation of trunk-highway flood disasters was completed. The evaluation results indicate that the risk evaluation is consistent with the actual situation.

  17. Regional Risk Evaluation of Flood Disasters for the Trunk-Highway in Shaanxi, China.

    Science.gov (United States)

    Qi, Hong-Liang; Tian, Wei-Ping; Li, Jia-Chun

    2015-10-29

    Due to the complicated environment there are various types of highway disasters in Shaanxi Province (China). The damages caused are severe, losses are heavy, and have rapidly increased over the years, especially those caused by flood disasters along the rivers in mountainous areas. Therefore, research on risk evaluations, which play important roles in the prevention and mitigation of highway disasters are very important. An evaluation model was established based on the superposition theory of regional influencing factors to highway flood disasters. Based on the formation mechanism and influencing factors of highway flood disasters, the main influencing factors were selected. These factors include rainstorms, terrain slopes, soil types, vegetation coverage and regional river density, which are based on evaluation indexes from climate conditions and underlying surface of the basin. A regional risk evaluation of highway flood disasters in Shaanxi was established using GIS. The risk index was divided into five levels using statistical methods, in accordance with the regional characteristics of highway flood disasters. Considering the difference in upfront investments, road grade, etc, between expressways and trunk-highways in China, a regional risk evaluation of trunk-highway flood disasters was completed. The evaluation results indicate that the risk evaluation is consistent with the actual situation.

  18. Acceptability of the Risk Importance Measures in Evaluation of a Change

    International Nuclear Information System (INIS)

    Dimitrijevic, V. B.; Chapman, J. R.

    1996-01-01

    In this paper, the authors discuss insights gained from evaluating changes to plant design and operational practices. Evaluation of a change is performed in order to provide an answer to two fundamental questions: what is the impact and is the impact acceptable? In order to determine 'the acceptability of an impact', the risk-based technologies today provide various ranking schemes. They are based on the existing IPE studies or PSA models and use of standard risk importance measures. In 'ad hoc' applications of risk importance measures, the specific nature of the analyzed change is often neglected. This paper attempts to capture the most common problems in the application of importance measures, and defines the limits of this application. The authors' position is that the use of risk importance information as the sole basis to accept or reject with ranking results, after the basis for the rank is meaningfully established. (author)

  19. Risk-based evaluation of Allowed Outage Times (AOTs) considering risk of shutdown

    International Nuclear Information System (INIS)

    Mankamo, T.; Kim, I.S.; Samanta, P.K.

    1992-01-01

    When safety systems fail during power operation, Technical Specifications (TS) usually limit the repair within Allowed Outage Time (AOT). If the repair cannot be completed within the AOT, or no AOT is allowed, the plant is required to be shut down for the repair. However, if the capability to remove decay heat is degraded, shutting down the plant with the need to operate the affected decay-heat removal systems may impose a substantial risk compared to continued power operation over a usual repair time. Thus, defining a proper AOT in such situations can be considered as a risk-comparison between the repair in frill power state with a temporarily increased level of risk, and the altemative of shutting down the plant for the repair in zero power state with a specific associated risk. The methodology of the risk-comparison approach, with a due consideration of the shutdown risk, has been further developed and applied to the AOT considerations of residual heat removal and standby service water systems of a boiling water reactor (BWR) plant. Based on the completed work, several improvements to the TS requirements for the systems studied can be suggested

  20. Risk Evaluation on UHV Power Transmission Construction Project Based on AHP and FCE Method

    OpenAIRE

    Huiru Zhao; Sen Guo

    2014-01-01

    Ultra high voltage (UHV) power transmission construction project is a high-tech power grid construction project which faces many risks and uncertainty. Identifying the risk of UHV power transmission construction project can help mitigate the risk loss and promote the smooth construction. The risk evaluation on “Zhejiang-Fuzhou” UHV power transmission construction project was performed based on analytic hierarchy process (AHP) and fuzzy comprehensive evaluation (FCE) method in this paper. Afte...

  1. Technology assessment HTR. Part 6. The radiological risks associated with the thorium-fuelled High Temperature Reactor. A comparative risk evaluation

    International Nuclear Information System (INIS)

    Dodd, D.H.; Van Hienen, J.F.A.

    1996-06-01

    This report presents the results of task B.3 of the 'Technology Assessment of the High Temperature Reactor' project. The objective of task B.3 was to evaluate the radiological risks to the general public associated with the sustainable HTGR cycle. Since the technologies to be used at several stages of this fuel cycle are still in the design phase and since a detailed specification of this fuel cycle has not yet been developed, the emphasis was on obtaining a global impression of the risk associated with a generic thorium-based HTGR fuel cycle. This impression was obtained by performing a comparative risk analysis on the basis of data given in the literature. As reference for the comparison a generic uranium fuel led LWR cycle was used. The structure of the report is as follows. In Chapter 2 the general methodology for assessing the radiological risks associated with nuclear installations is described. An overview is given of the measures commonly used to quantify these risks. In Chapter 3 an overview is given of the different stages of the reference uranium fuel led LWR cycle and the thorium fuel led HTGR cycle. In Chapter 4 a stage-by-stage analysis is given of the radiological risks associated with the two fuel cycles. Finally, in Chapter 5 an evaluation is made of the radiological risks associated with the LWR and HTGR cycles and with thorium and uranium fuels. In Appendix A the production and releases of 14 C for LWR and HTGR fuel cycle facilities is considered in detail. 11 figs., 10 tabs., 10 refs

  2. Track 6: safety and risk management. Plant operational risk management. Plant Configuration Risk Assessment Methodology Development for Periodic Maintenance

    International Nuclear Information System (INIS)

    Yang, Huichang; Chung, Chang Hyun; Sung, Key Yong

    2001-01-01

    As the operation experiences of nuclear power plants (NPPs) in Korea accumulate and NPP safety functions become enhanced, the role of stable and optimal NPP operation within acceptable safety criteria becomes important at present. To accomplish the goal of safe and optimal operation, maintenance and its related activities should be regarded as the issues of most concern. Studies of methodologies for maintenance improvement and optimization have focused on system performance rather than on the hardware itself. From this point of view, the probabilistic methods are most useful. In terms of risk including core damage frequency and unavailability, the cause that might impact plant safety during normal maintenance activities can be identified and evaluated effectively. The results from these probabilistic analyses can provide insightful information for the reallocation of risk-contributing maintenance activity. This information can be utilized in a way that separates the significant risk-contributing maintenance activities from each other unless they are timely related. In Korea, the risk-monitoring program for operating NPPs is under development and will be implemented in 2003. To accomplish the risk-monitoring program objectives, suitable risk evaluation methods should be developed before the implementation of the risk-monitoring program. The plant configuration assessment methodology was developed for these reasons, and this method is to incorporate the field experiences into the risk calculation exactly within the limit of probabilistic methods. During normal plant operation, the plant operational risk changes frequently depending on the status of the plant system and the arrangement of the components. Specific plant systems or components are typically removed from service because of random equipment failure, planned preventive/predictive maintenance, corrective maintenance, surveillance testing, and operational bypass activities, and such events usually impact the

  3. Development and evaluation of a risk communication curriculum for medical students

    NARCIS (Netherlands)

    Han, P.K.; Joekes, K.; Elwyn, G.; Mazor, K.M.; Thomson, R.; Sedgwick, P.; Ibison, J.; Wong, J.B.

    2014-01-01

    OBJECTIVE: To develop, pilot, and evaluate a curriculum for teaching clinical risk communication skills to medical students. METHODS: A new experience-based curriculum, "Risk Talk," was developed and piloted over a 1-year period among students at Tufts University School of Medicine. An experimental

  4. Evaluation of an inpatient fall risk screening tool to identify the most critical fall risk factors in inpatients.

    Science.gov (United States)

    Hou, Wen-Hsuan; Kang, Chun-Mei; Ho, Mu-Hsing; Kuo, Jessie Ming-Chuan; Chen, Hsiao-Lien; Chang, Wen-Yin

    2017-03-01

    To evaluate the accuracy of the inpatient fall risk screening tool and to identify the most critical fall risk factors in inpatients. Variations exist in several screening tools applied in acute care hospitals for examining risk factors for falls and identifying high-risk inpatients. Secondary data analysis. A subset of inpatient data for the period from June 2011-June 2014 was extracted from the nursing information system and adverse event reporting system of an 818-bed teaching medical centre in Taipei. Data were analysed using descriptive statistics, receiver operating characteristic curve analysis and logistic regression analysis. During the study period, 205 fallers and 37,232 nonfallers were identified. The results revealed that the inpatient fall risk screening tool (cut-off point of ≥3) had a low sensitivity level (60%), satisfactory specificity (87%), a positive predictive value of 2·0% and a negative predictive value of 99%. The receiver operating characteristic curve analysis revealed an area under the curve of 0·805 (sensitivity, 71·8%; specificity, 78%). To increase the sensitivity values, the Youden index suggests at least 1·5 points to be the most suitable cut-off point for the inpatient fall risk screening tool. Multivariate logistic regression analysis revealed a considerably increased fall risk in patients with impaired balance and impaired elimination. The fall risk factor was also significantly associated with days of hospital stay and with admission to surgical wards. The findings can raise awareness about the two most critical risk factors for falls among future clinical nurses and other healthcare professionals and thus facilitate the development of fall prevention interventions. This study highlights the needs for redefining the cut-off points of the inpatient fall risk screening tool to effectively identify inpatients at a high risk of falls. Furthermore, inpatients with impaired balance and impaired elimination should be closely

  5. A Hybrid Approach for Evaluating Faulty Behavior Risk of High-Risk Operations Using ANP and Evidence Theory

    Directory of Open Access Journals (Sweden)

    Xia-Zhong Zheng

    2017-01-01

    Full Text Available Hydropower project construction is a high-risk operation, where accidents occur frequently. Moreover, the factors leading to accidents are often human factors, so safety evaluation of these factors for the hydropower projects’ work system is very significant. The Human Factors Analysis and Classification System (HFACS framework is applied to build evaluation system. In the evaluation process, correlation analysis is used to form the intercriteria analysis matrix that helps the decision makers to build impact relation matrix. Factor weights are calculated by the Analytic Network Process (ANP. In the index value determination step, the evidence theory is used to eliminate the conflicts of three decision makers and the index values are then calculated. The faulty behavior risk (FBR assessment value is finally obtained. The proposed method is practical and its applicability is proved by an example.

  6. Risk analysis in radiosurgery treatments using risk matrices

    International Nuclear Information System (INIS)

    Delgado, J. M.; Sanchez Cayela, C.; Ramirez, M. L.; Perez, A.

    2011-01-01

    The aim of this study is the risk analysis process stereotactic single-dose radiotherapy and evaluation of those initiating events that lead to increased risk and a possible solution in the design of barriers.

  7. Exploring risk communication - results of a research project focussed on effectiveness evaluation

    Science.gov (United States)

    Charrière, Marie; Bogaard, Thom; Junier, Sandra; Mostert, Erik

    2016-04-01

    The need for effective science communication and outreach efforts is widely acknowledged in the academic community. In the field of Disaster Risk Reduction, the importance of communication is clearly stressed, e.g. in the newly adopted Sendai Framework for Disaster Risk Reduction 2015-2030 (under the 1st priority of action: understanding disaster risk). Consequently, we see increasing risk communication activities. However, the effectiveness of these activities is rarely evaluated. To address this gap, several research activities were conducted in the context of the Marie Curie Initial Training Network "Changes", the results of which we will present and discuss. First, results of a literature review show, among others, that research on effectiveness is mainly focussed on the assessment of users' needs and their ability to understand the content, rather than on the final impact of the risk communication efforts. Moreover, lab-environment research is more often undertaken than assessment of real communication efforts. Second, a comparison between perceptions of risk managers and the general public of risk communication in a French Alps Valley highlighted a gap between the two groups in terms of amount of information needed (who wants more), the important topics to address (what) and the media to use (how). Third, interviews with developers of smartphone applications for disseminating avalanche risk information showed a variety of current practices and the absence of measurements of real their effectiveness. However, our analysis allowed identifying good practices that can be an inspiration for risk communication related to other hazards. Fourth, an exhibition has been set up following a collaborative approached based on stakeholder engagement. Using a pre/post-test design, the immediate impact of the exhibition, which aimed at increasing the risk awareness of the population (Ubaye Valley, France), was measured. The data obtained suggests that visiting the exhibition

  8. A risk evaluation model using on-site meteorological data

    International Nuclear Information System (INIS)

    Kang, C.S.

    1979-01-01

    A model is considered in order to evaluate the potential risk from a nuclear facility directly combining the on site meteorological data. The model is utilized to evaluate the environmental consequences from the routine releases during normal plant operation as well as following postulated accidental releases. The doses to individual and risks to the population-at-large are also analyzed in conjunction with design of rad-waste management and safety systems. It is observed that the conventional analysis, which is done in two separate unaffiliated phases of releases and atmospheric dispersion tends to result in unnecessary over-design of the systems because of high resultant doses calculated by multiplication of two extreme values. (author)

  9. Operation and evaluation of online risk communication assistant tool, 'ORCAT'

    International Nuclear Information System (INIS)

    Kimura, Hiroshi; Katsumura, Soichiro; Furuta, Kazuo; Matsumura, Kenichi; Tanaka, Hiroshi

    2005-01-01

    Risk communication about the high-level radioactive waste (HLW) disposal is necessary for public acceptance of HLW disposal program. Online Risk Communication Assistant Tool (ORCAT) system is developed in order to support risk communication for high-level radioactive disposal on World Wide Web. We have carried out two test operations of ORCAT system. First test operation is carried out from Jun. 26 to Feb. 13, 2003. After the first operation, we improved the ORCAT system, and carried out the second test operation from Dec. 4 to 22, 2004. In the second test operation, 20 participants replayed the questionnaire about usability of ORCAT system. In consequence, we found that the ORCAT system remains what need to refine, but is evaluated useful to the risk communication about the HLW disposal. (author)

  10. Evaluation of the Reproductive and Developmental Risks of Caffeine

    Science.gov (United States)

    Brent, Robert L; Christian, Mildred S; Diener, Robert M

    2011-01-01

    A risk analysis of in utero caffeine exposure is presented utilizing epidemiological studies and animal studies dealing with congenital malformation, pregnancy loss, and weight reduction. These effects are of interest to teratologists, because animal studies are useful in their evaluation. Many of the epidemiology studies did not evaluate the impact of the “pregnancy signal,” which identifies healthy pregnancies and permits investigators to identify subjects with low pregnancy risks. The spontaneous abortion epidemiology studies were inconsistent and the majority did not consider the confounding introduced by not considering the pregnancy signal. The animal studies do not support the concept that caffeine is an abortafacient for the wide range of human caffeine exposures. Almost all the congenital malformation epidemiology studies were negative. Animal pharmacokinetic studies indicate that the teratogenic plasma level of caffeine has to reach or exceed 60 µg/ml, which is not attainable from ingesting large amounts of caffeine in foods and beverages. No epidemiological study described the “caffeine teratogenic syndrome.” Six of the 17 recent epidemiology studies dealing with the risk of caffeine and fetal weight reduction were negative. Seven of the positive studies had growth reductions that were clinically insignificant and none of the studies cited the animal literature. Analysis of caffeine's reproductive toxicity considers reproducibility and plausibility of clinical, epidemiological, and animal data. Moderate or even high amounts of beverages and foods containing caffeine do not increase the risks of congenital malformations, miscarriage or growth retardation. Pharmacokinetic studies markedly improve the ability to perform the risk analyses. Birth Defects Res (Part B) 92:152–187, 2011. © 2011 Wiley-Liss, Inc. PMID:21370398

  11. A risk-based evaluation of LMFBR containment response under core disruptive accident conditions

    International Nuclear Information System (INIS)

    Hartung, J.; Berk, S.

    1978-01-01

    Probabilistic risk methodology is utilized to evaluate the failure modes and effects of LMFBR containment systems under Core Disruptive Accident (CDA) conditions. First, the potential causes of LMFBR containment failure under CDA conditions are discussed and categorized. Then, a simple scoping-type risk assessment of a reference design is presented to help place these potential causes of failure in perspective. The highest risk containment failure modes are identified for the reference design, and several design and research and development options which appear capable of reducing these risks are discussed. The degree to which large LMFBR containment systems must mitigate the consequences of CDA's to achieve a level of risk (for LMFBR's) comparable to the already very low risk of contemporary LWR's is explored. Based on the results of this evaluation, several suggestions are offered concerning CDA-related design goals and research and development priorities for large LMFBR's. (author)

  12. State of risk assessment

    International Nuclear Information System (INIS)

    Conrad, J.

    1978-03-01

    In view of the growing importance assumed in recent years by scientific work on the calculation, quantification, evaluation and acceptance as well as behavior in the face of risks in general and more specifically, the risks of large industrial plants, the report attempts to provide a survey of the current situation, results and evaluation of this new branch of research, risk assessment. The emphasis of the report is on the basic discussion and criticism of the theoretical and methodological approaches used in the field of risk assessment (section 3). It is concerned above all with - methodical problems of determining and quantifying risks (3.1) - questions of the possibility of risk evaluation and comp arison (3.1, 3.2) - the premises of normative and empirical studies on decision making under risk (3.2, 3.3) - investigations into society's acceptance of risks involved in the introduction of new technologies (3.4) - attempts to combine various aspects of the field of risk assessment in a unified concept (3.5, 3.6, 3.7). Because risk assessment is embedded in the framework of decision theory and technology assessment, it can be implicitly evaluated at a more general level within this framework, as far as its possibilities and weaknesses of method and application are concerned (section 4). Sections 2 and 5 deal with the social context of origin and utilization of risk assessment. Finally, an attempt is made at a summary indicating the possible future development of risk assessment. (orig./HP) [de

  13. Risk analysis

    International Nuclear Information System (INIS)

    Correa Lizarazu, X.

    2013-01-01

    The power point presentation Colombia risk evaluation experiences, sanitarian regulations evolution, chemical dangers food, biological dangers food, codex alimentarius, trade, industrial effects, dangers identification, data collection and risk profile

  14. Ensemble of trees approaches to risk adjustment for evaluating a hospital's performance.

    Science.gov (United States)

    Liu, Yang; Traskin, Mikhail; Lorch, Scott A; George, Edward I; Small, Dylan

    2015-03-01

    A commonly used method for evaluating a hospital's performance on an outcome is to compare the hospital's observed outcome rate to the hospital's expected outcome rate given its patient (case) mix and service. The process of calculating the hospital's expected outcome rate given its patient mix and service is called risk adjustment (Iezzoni 1997). Risk adjustment is critical for accurately evaluating and comparing hospitals' performances since we would not want to unfairly penalize a hospital just because it treats sicker patients. The key to risk adjustment is accurately estimating the probability of an Outcome given patient characteristics. For cases with binary outcomes, the method that is commonly used in risk adjustment is logistic regression. In this paper, we consider ensemble of trees methods as alternatives for risk adjustment, including random forests and Bayesian additive regression trees (BART). Both random forests and BART are modern machine learning methods that have been shown recently to have excellent performance for prediction of outcomes in many settings. We apply these methods to carry out risk adjustment for the performance of neonatal intensive care units (NICU). We show that these ensemble of trees methods outperform logistic regression in predicting mortality among babies treated in NICU, and provide a superior method of risk adjustment compared to logistic regression.

  15. RISK VIP: Evaluation of Flood Risk on the French Railway Network Using an Innovative GIS Approach

    Directory of Open Access Journals (Sweden)

    Cheetham Mark

    2016-01-01

    Full Text Available Flooding can have significant direct and indirect negative effects on a railway network affecting both infrastructure and rail operations. Such impacts include the delaying or cancelling of train services, damage to railway structures or the implementation of costly maintenance and monitoring programs to ensure the safety and performance of the railway system. Identifying sections of railway line at risk from flooding allows appropriate actions to be targeted at specific areas and contributes to an effective asset management plan. Flooding of railway infrastructure can have numerous sources including surface water run-off, insufficient capacity of hydraulic structures or the inundation of embankments located in floodplains. Consequences of flooding include the destabilisation of structures (surface erosion of embankments or the undermining of bridge foundations, differential settlement of structures and damage to the track structure. This paper details an innovative approach developed at the SNCF using a Geographic Information System (GIS model to identify zones of the railway network at risk of different types of flooding. The GIS model RiskVIP has been constructed through the assessment of three distinct components of risk: “Vulnerability” (assessment of the susceptibility of the railway infrastructure to flood conditions, Intensity’ (capacity of a catchment to generate a flood flow, Probability’ (probability of a rainfall event.Through the application of decision trees, the component ‘Intensity’ has been characterised in the model by the physical properties of the catchment intercepted by the railway line (surface area of the catchment, slope and land cover characteristics and “Vulnerability” by the infrastructure itself (type, geometry and the presence of hydraulic structures. In order to evaluate its efficiency at identifying sites at risk of flooding, the model has been tested in the region of Languedoc-Roussillon in France

  16. Risk management frameworks for human health and environmental risks.

    Science.gov (United States)

    Jardine, Cindy; Hrudey, Steve; Shortreed, John; Craig, Lorraine; Krewski, Daniel; Furgal, Chris; McColl, Stephen

    2003-01-01

    -Making Framework for Identifying, Assessing and Managing Health Risks (Health Canada, 2000). 4. Canadian Environmental Protection Act: Human Health Risk Assessment of Priority Substances(Health Canada, 1994). 5. CSA-Q8550 Risk Management: Guidelines for Decision-Makers (Canada Standards Association, 1997). 6. Risk Assessment in the Federal Government: Managing the Process (US National Research Council, 1983). 7. Understanding Risk: Informing Decisions in a Democratic Society (US National Research Council, 1996). 8. Environmental Health Risk Assessment (enHealth Council of Australia, 2002). 9. A Framework for Ecological Risk Assessment (CCME, 1996). 10. Ecological Risk Assessments of Priority Substances Under the Canadian Environmental Protection Act (Environment Canada, 1996).11. Guidelines for Ecological Risk Assessment (US EPA, 1998b). 12. Proposed Model for Occupational Health Risk Assessment and Management (Rampal & Sadhra, 1999). Based on the extensive review of these frameworks, seven key elements that should be included in a comprehensive framework for human health, ecological, and occupational risk assessment and management were identified: 1. Problem formulation stage. 2. Stakeholder involvement. 3. Communication. 4. Quantitative risk assessment components. 5. Iteration and evaluation. 6. Informed decision making. 7. Flexibility. On the basis of this overarching approach to risk management, the following "checklist" to ensure a good risk management decision is proposed: - Make sure you're solving the right problem. - Consider the problem and the risk within the full context of the situation, using a broad perspective. - Acknowledge, incorporate, and balance the multiple dimensions of risk. - Ensure the highest degree of reliability for all components of the risk management process. - Involve interested and effected parties from the outset of the process. - Commit to honest and open communication between all parties. - Employ continuous evaluation throughout the process

  17. Concept of risk: risk assessment and nuclear safety

    International Nuclear Information System (INIS)

    Thompson, P.B.

    1980-01-01

    The dissertation is a critical examination of risk assessment and its role in public policy. Nuclear power safety safety issues are selected as the primary source of illustrations and examples. The dissertation examines how risk assessment studies develop a concept of risk which becomes decisive for policy choices. Risk-assessment techniques are interpreted as instruments which secure an evaluation of risk which, in turn, figures prominently in technical reports on nuclear power. The philosophical critique is mounted on two levels. First, an epistemological critique surveys distinctions between the technical concept of risk and more familiar senses of risk. The critique shows that utilization of risk assessment re-structures the concept of risk. The technical concept is contrasted to the function of risk within a decision-maker's conceptual agenda and hierarchy of values. Second, an ethical critique exposes the value commitments of risk assessment recommendations. Although some of these values might be defended for policy decisions, the technical character of risk assessment obfuscates normative issues. Risk assessment is shown to be a form of factual enquiry which, nonetheless, represents a commitment to a specific selection of ethical and social values. Risk assessment should not be interpreted as a primary guide to decision unless the specific values incorporated into its concept of risk are stated explicitly and justified philosophically. Such a statement would allow value questions which have been sublimated by the factual tone of the analytic techniques to be debated on clear, social and ethical grounds

  18. Holistic Disaster Risk Evaluation for the Urban Risk Management Plan of Manizales, Colombia

    Institute of Scientific and Technical Information of China (English)

    Martha Liliana Carre(n)o; Omar-Darío Cardona; Alex H.Barbat; Dora Catalina Suarez; María del Pilar Perez; Lizardo Narvaez

    2017-01-01

    Disaster risk depends on both the physical vulnerability and a wide range of social,economic,and environmental aspects of a society.For a better risk understanding,a holistic or integrated perspective was considered when risk was assessed for the city of Manizales,Colombia.This assessment accounts not only for the expected physical damage and loss,but also for the socioeconomic vulnerability factors that favor secondorder effects in a disaster.This comprehensive approach allows the identification of different aspects related to physical vulnerability,social fragility,and lack of resilience that can be improved,thus enhancing integrated disaster risk management actions.The outcomes of this comprehensive assessment are currently being used as input to update the disaster risk management plan of Manizales.

  19. Evaluation of risk factors for vancomycin-induced nephrotoxicity.

    Science.gov (United States)

    Park, So Jin; Lim, Na Ri; Park, Hyo Jung; Yang, Jae Wook; Kim, Min-Ji; Kim, Kyunga; In, Yong Won; Lee, Young Mee

    2018-05-09

    Background Vancomycin is a glycopeptide antibiotic of choice for the treatment of serious infections caused by multi-resistant Gram-positive bacteria. However, vancomycin-associated nephrotoxicity (VAN) often limits its use. Previous data suggested a few risk factors of VAN, including higher mean vancomycin trough level, higher daily doses, old age, long duration of vancomycin therapy, and concomitant nephrotoxins. Objective To evaluate the incidence and risk factors of VAN and determine whether higher vancomycin trough concentrations were associated with a greater risk for VAN. Settings A retrospective, observational, single-center study at the 1960-bed university-affiliated tertiary care hospital (Samsung Medical Center), Seoul, Korea. Method A retrospective analysis of adult patients who received vancomycin parenterally in a tertiary care medical center from March 1, 2013 to June 30, 2013 was performed. We excluded patients with a baseline serum creatinine level > 2 mg/dL and those who had a history of end-stage renal disease and dialysis at baseline. The clinical characteristics were compared between patients with nephrotoxicity and those without nephrotoxicity to identify the risk factors associated with VAN. Main outcome measure Incidence of VAN and VAN-associated risk factors were analyzed. Results Of the 315 vancomycin-treated patients, nephrotoxicity occurred in 15.2% of the patients. In multivariate analysis, higher vancomycin trough concentrations of > 20 mg∕L (OR 9.57, 95% CI 2.49-36.83, p < 0.01) and intensive care unit (ICU) residence (OR 2.86, 95% CI 1.41-5.82, p < 0.01) were independently associated with VAN. Conclusion Our findings suggest that higher vancomycin trough levels and ICU residence might be associated with a greater risk for VAN. More careful monitoring of vancomycin serum trough levels and patient status might facilitate the timely prevention of VAN.

  20. Evaluation of a visual risk communication tool: effects on knowledge and perception of blood transfusion risk.

    Science.gov (United States)

    Lee, D H; Mehta, M D

    2003-06-01

    Effective risk communication in transfusion medicine is important for health-care consumers, but understanding the numerical magnitude of risks can be difficult. The objective of this study was to determine the effect of a visual risk communication tool on the knowledge and perception of transfusion risk. Laypeople were randomly assigned to receive transfusion risk information with either a written or a visual presentation format for communicating and comparing the probabilities of transfusion risks relative to other hazards. Knowledge of transfusion risk was ascertained with a multiple-choice quiz and risk perception was ascertained by psychometric scaling and principal components analysis. Two-hundred subjects were recruited and randomly assigned. Risk communication with both written and visual presentation formats increased knowledge of transfusion risk and decreased the perceived dread and severity of transfusion risk. Neither format changed the perceived knowledge and control of transfusion risk, nor the perceived benefit of transfusion. No differences in knowledge or risk perception outcomes were detected between the groups randomly assigned to written or visual presentation formats. Risk communication that incorporates risk comparisons in either written or visual presentation formats can improve knowledge and reduce the perception of transfusion risk in laypeople.

  1. Guidance on a harmonised framework for pest risk assessment and the identification and evaluation of pest risk management options by EFSA

    DEFF Research Database (Denmark)

    Baker, R.; Candresse, T.; Dormannsné Simon, E.

    2010-01-01

    The Scientific Panel on Plant Health was requested by EFSA to develop a guidance document on a harmonised framework for risk assessment of organisms harmful to plants and plant products and the identification and evaluation of risk management options. The document provides guiding principles on a...

  2. Risk Evaluation of Railway Coal Transportation Network Based on Multi Level Grey Evaluation Model

    Science.gov (United States)

    Niu, Wei; Wang, Xifu

    2018-01-01

    The railway transport mode is currently the most important way of coal transportation, and now China’s railway coal transportation network has become increasingly perfect, but there is still insufficient capacity, some lines close to saturation and other issues. In this paper, the theory and method of risk assessment, analytic hierarchy process and multi-level gray evaluation model are applied to the risk evaluation of coal railway transportation network in China. Based on the example analysis of Shanxi railway coal transportation network, to improve the internal structure and the competitiveness of the market.

  3. A quantitative and comparative evaluation of the risks from nuclear power plants

    International Nuclear Information System (INIS)

    Vignes, S.; Bertin, M.; Nenot, J.C.

    1980-01-01

    All the significant data for the assessment of risks from the operation of nuclear power plants was collected and these risks were compared with all the risks of modern life. The scientific bases for the evaluation of individual risks and detriment were defined by UNSCEAR (1977) and by ICRP 26 (1978). In different industries, the risk of death from long term occupational illness is about 130 to 14,000 per million workers. For accidental deaths, the risk is estimated at about 16 to 1,600. The risk for the nuclear industry is lower than 100 per million workers. Comparisons are made with different causes of lethality: deaths from atmospheric pollution (sulfur compounds and dusts) related to fossile fuel combustion; iatrogenic accidents attributed to some drugs used in medicine or to other kind of treatment; calculated mortality for workers exposed to asestosis. The nuclear industr of the safest. The only risk to be considered is the major accident, the probability of which is very low. (H.K.)

  4. Evaluation of Risk Management Strategies for a Low-Cost, High-Risk Project

    Science.gov (United States)

    Shishko, Robert; Jorgensen, Edward J.

    1996-01-01

    This paper summarizes work in progress to define and implement a risk management process tailored to a low-cost, high-risk, NASA mission -the Microrover Flight Experiment (MFEX, commonly called the Mars microrover).

  5. Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

    Science.gov (United States)

    Kuchenbaecker, Karoline B.; McGuffog, Lesley; Barrowdale, Daniel; Lee, Andrew; Soucy, Penny; Healey, Sue; Dennis, Joe; Lush, Michael; Robson, Mark; Spurdle, Amanda B.; Ramus, Susan J.; Mavaddat, Nasim; Terry, Mary Beth; Neuhausen, Susan L.; Hamann, Ute; Southey, Melissa; John, Esther M.; Chung, Wendy K.; Daly, Mary B.; Buys, Saundra S.; Goldgar, David E.; Dorfling, Cecilia M.; van Rensburg, Elizabeth J.; Ding, Yuan Chun; Ejlertsen, Bent; Gerdes, Anne-Marie; Hansen, Thomas V. O.; Slager, Susan; Hallberg, Emily; Benitez, Javier; Osorio, Ana; Cohen, Nancy; Lawler, William; Weitzel, Jeffrey N.; Peterlongo, Paolo; Pensotti, Valeria; Dolcetti, Riccardo; Barile, Monica; Bonanni, Bernardo; Azzollini, Jacopo; Manoukian, Siranoush; Peissel, Bernard; Radice, Paolo; Savarese, Antonella; Papi, Laura; Giannini, Giuseppe; Fostira, Florentia; Konstantopoulou, Irene; Adlard, Julian; Brewer, Carole; Cook, Jackie; Davidson, Rosemarie; Eccles, Diana; Eeles, Ros; Ellis, Steve; Frost, Debra; Hodgson, Shirley; Izatt, Louise; Lalloo, Fiona; Ong, Kai-ren; Godwin, Andrew K.; Arnold, Norbert; Dworniczak, Bernd; Engel, Christoph; Gehrig, Andrea; Hahnen, Eric; Hauke, Jan; Kast, Karin; Meindl, Alfons; Niederacher, Dieter; Schmutzler, Rita Katharina; Varon-Mateeva, Raymonda; Wang-Gohrke, Shan; Wappenschmidt, Barbara; Barjhoux, Laure; Collonge-Rame, Marie-Agnès; Elan, Camille; Golmard, Lisa; Barouk-Simonet, Emmanuelle; Lesueur, Fabienne; Mazoyer, Sylvie; Sokolowska, Joanna; Stoppa-Lyonnet, Dominique; Isaacs, Claudine; Claes, Kathleen B. M.; Poppe, Bruce; de la Hoya, Miguel; Garcia-Barberan, Vanesa; Aittomäki, Kristiina; Nevanlinna, Heli; Ausems, Margreet G. E. M.; de Lange, J. L.; Gómez Garcia, Encarna B.; Hogervorst, Frans B. L.; Kets, Carolien M.; Meijers-Heijboer, Hanne E. J.; Oosterwijk, Jan C.; Rookus, Matti A.; van Asperen, Christi J.; van den Ouweland, Ans M. W.; van Doorn, Helena C.; van Os, Theo A. M.; Kwong, Ava; Olah, Edith; Diez, Orland; Brunet, Joan; Lazaro, Conxi; Teulé, Alex; Gronwald, Jacek; Jakubowska, Anna; Kaczmarek, Katarzyna; Lubinski, Jan; Sukiennicki, Grzegorz; Barkardottir, Rosa B.; Chiquette, Jocelyne; Agata, Simona; Montagna, Marco; Teixeira, Manuel R.; Park, Sue Kyung; Olswold, Curtis; Tischkowitz, Marc; Foretova, Lenka; Gaddam, Pragna; Vijai, Joseph; Pfeiler, Georg; Rappaport-Fuerhauser, Christine; Singer, Christian F.; Tea, Muy-Kheng M.; Greene, Mark H.; Loud, Jennifer T.; Rennert, Gad; Imyanitov, Evgeny N.; Hulick, Peter J.; Hays, John L.; Piedmonte, Marion; Rodriguez, Gustavo C.; Martyn, Julie; Glendon, Gord; Mulligan, Anna Marie; Andrulis, Irene L.; Toland, Amanda Ewart; Jensen, Uffe Birk; Kruse, Torben A.; Pedersen, Inge Sokilde; Thomassen, Mads; Caligo, Maria A.; Teo, Soo-Hwang; Berger, Raanan; Friedman, Eitan; Laitman, Yael; Arver, Brita; Borg, Ake; Ehrencrona, Hans; Rantala, Johanna; Olopade, Olufunmilayo I.; Ganz, Patricia A.; Nussbaum, Robert L.; Bradbury, Angela R.; Domchek, Susan M.; Nathanson, Katherine L.; Arun, Banu K.; James, Paul; Karlan, Beth Y.; Lester, Jenny; Simard, Jacques; Pharoah, Paul D. P.; Offit, Kenneth; Couch, Fergus J.; Chenevix-Trench, Georgia; Easton, Douglas F.

    2017-01-01

    Background: Genome-wide association studies (GWAS) have identified 94 common single-nucleotide polymorphisms (SNPs) associated with breast cancer (BC) risk and 18 associated with ovarian cancer (OC) risk. Several of these are also associated with risk of BC or OC for women who carry a pathogenic mutation in the high-risk BC and OC genes BRCA1 or BRCA2. The combined effects of these variants on BC or OC risk for BRCA1 and BRCA2 mutation carriers have not yet been assessed while their clinical management could benefit from improved personalized risk estimates. Methods: We constructed polygenic risk scores (PRS) using BC and OC susceptibility SNPs identified through population-based GWAS: for BC (overall, estrogen receptor [ER]–positive, and ER-negative) and for OC. Using data from 15 252 female BRCA1 and 8211 BRCA2 carriers, the association of each PRS with BC or OC risk was evaluated using a weighted cohort approach, with time to diagnosis as the outcome and estimation of the hazard ratios (HRs) per standard deviation increase in the PRS. Results: The PRS for ER-negative BC displayed the strongest association with BC risk in BRCA1 carriers (HR = 1.27, 95% confidence interval [CI] = 1.23 to 1.31, P = 8.2×10−53). In BRCA2 carriers, the strongest association with BC risk was seen for the overall BC PRS (HR = 1.22, 95% CI = 1.17 to 1.28, P = 7.2×10−20). The OC PRS was strongly associated with OC risk for both BRCA1 and BRCA2 carriers. These translate to differences in absolute risks (more than 10% in each case) between the top and bottom deciles of the PRS distribution; for example, the OC risk was 6% by age 80 years for BRCA2 carriers at the 10th percentile of the OC PRS compared with 19% risk for those at the 90th percentile of PRS. Conclusions: BC and OC PRS are predictive of cancer risk in BRCA1 and BRCA2 carriers. Incorporation of the PRS into risk prediction models has promise to better inform decisions on cancer risk management. PMID

  6. A spatial assessment framework for evaluating flood risk under extreme climates.

    Science.gov (United States)

    Chen, Yun; Liu, Rui; Barrett, Damian; Gao, Lei; Zhou, Mingwei; Renzullo, Luigi; Emelyanova, Irina

    2015-12-15

    Australian coal mines have been facing a major challenge of increasing risk of flooding caused by intensive rainfall events in recent years. In light of growing climate change concerns and the predicted escalation of flooding, estimating flood inundation risk becomes essential for understanding sustainable mine water management in the Australian mining sector. This research develops a spatial multi-criteria decision making prototype for the evaluation of flooding risk at a regional scale using the Bowen Basin and its surroundings in Queensland as a case study. Spatial gridded data, including climate, hydrology, topography, vegetation and soils, were collected and processed in ArcGIS. Several indices were derived based on time series of observations and spatial modeling taking account of extreme rainfall, evapotranspiration, stream flow, potential soil water retention, elevation and slope generated from a digital elevation model (DEM), as well as drainage density and proximity extracted from a river network. These spatial indices were weighted using the analytical hierarchy process (AHP) and integrated in an AHP-based suitability assessment (AHP-SA) model under the spatial risk evaluation framework. A regional flooding risk map was delineated to represent likely impacts of criterion indices at different risk levels, which was verified using the maximum inundation extent detectable by a time series of remote sensing imagery. The result provides baseline information to help Bowen Basin coal mines identify and assess flooding risk when making adaptation strategies and implementing mitigation measures in future. The framework and methodology developed in this research offers the Australian mining industry, and social and environmental studies around the world, an effective way to produce reliable assessment on flood risk for managing uncertainty in water availability under climate change. Copyright © 2015. Published by Elsevier B.V.

  7. Chemical mixtures: Evaluation of risk for child-specific exposures in a multi-stressor environment

    International Nuclear Information System (INIS)

    Pohl, H.R.; Abadin, H.G.

    2008-01-01

    Evaluating the health impact from exposure to chemical mixtures is multifaceted. One component is exposure. Exposure, and consequently risk assessment for mixtures and chemicals in general, are often viewed in terms of a given exposure to a given population at a given location over a given time period. However, environmental exposures are present throughout human lifetime. As a result, an evaluation of risk must include the distinctive characteristics related to chemical exposures which will impact risk depending upon the particular life stage where exposure occurs. Risks to offspring may be associated with unique exposures in utero, during infancy, childhood, or adolescent periods. For example, exposure of infants to anthropogenic chemicals via breast milk may be of concern. The Agency for Toxic Substances and Disease Registry's (ATSDR's) approach to evaluating risks associated with exposure to mixtures of chemicals is presented. In addition to the breast milk issues, indoor exposure to combined air pollutants, drinking water contaminants, and soil and dust contaminants are discussed. The difference between a mixture's risk evaluation for children and adults is in the distinct exposure scenarios resulting from variations in behavior, physiology, and/or pharmacokinetics between adults and children rather than in the method for the specific mixtures evaluation per se

  8. The risk evaluation of a model of a high-level waste solidification plant

    International Nuclear Information System (INIS)

    Bruecher, H.

    1977-02-01

    In this report the risk associated with the operation of a plant for vitrification of high-level liquid waste is evaluated. Considerung risk assessment it turns out that the important accidents occur during off-gas cleaning. On the other hand effects of explosions in the process equipment don't contribute very much to the overall risk. These data are compared with the risk resulting from routine discharge of the plant. It is of the same magnitude as or greater than the most important accident risks. (orig.) [de

  9. THE IMPORTANCE OF EVALUATION OF RISK MANAGEMENT IN BUSINESS

    Directory of Open Access Journals (Sweden)

    SLOBODAN POPOVIĆ

    2015-10-01

    Full Text Available Economies with dominant private ownership and developed market institutions build their prosperity on a firm`s goal function in a form of maximization owner`s wealth. Financial situation of business organization is most important indicate that shows level of financial health. The creation of value for the owners imply two matters simultaneously competitive advantage and the evaluation of economic effects. Among economic activities, establishes the different types of addiction. In this work authors draw attention to two categories: the functional and stochastic. Case studies will be cash flows of investment and the contribution of the stochastic component of the risk of enterprise value. Methodological dominated analytical and descriptive methods. Management in the process of evaluation of investment seen what happens behind the projections of cash flows and estimates of available chances for possible modifications. The purpose of the discussion in this section refers to the warning that the application of the rules of net present values does not mean the completion of the management process at the moment of the decision on the selection of investments. In this study, we analyze the influence of stochastic risk in the creation of enterprise value, especially if the risk is managed improperly. In this connection, the starting hypothesis is that adequately compensate for risk has a positive effect on new investments and reduce the antagonism of shareholders and other creditors of the company.

  10. The approach of risk and safety evaluation in radioactive waste transport

    International Nuclear Information System (INIS)

    Vieru, G.

    1996-01-01

    Within Institute for Nuclear Research (INR) Pitesti, qualification tests were performed on packages, designed for transport and storage of low activity radioactive waste. Risk assessment activities aiming the evaluation of risk categories that many arise either during accident free transport or during accident conditions of waste transportation to the disposal center, in Romania, have been approached. The accident rates calculation, the distribution within accident scenarios and overall effective collective dose (man.Sv/year),for routine road transportation and the accidental Risk (man.Sv/Year) were determined

  11. Evaluation model for safety capacity of chemical industrial park based on acceptable regional risk

    Institute of Scientific and Technical Information of China (English)

    Guohua Chen; Shukun Wang; Xiaoqun Tan

    2015-01-01

    The paper defines the Safety Capacity of Chemical Industrial Park (SCCIP) from the perspective of acceptable regional risk. For the purpose of exploring the evaluation model for the SCCIP, a method based on quantitative risk assessment was adopted for evaluating transport risk and to confirm reasonable safety transport capacity of chemical industrial park, and then by combining with the safety storage capacity, a SCCIP evaluation model was put forward. The SCCIP was decided by the smaller one between the largest safety storage capacity and the maximum safety transport capacity, or else, the regional risk of the park will exceed the acceptable level. The developed method was applied to a chemical industrial park in Guangdong province to obtain the maximum safety transport capacity and the SCCIP. The results can be realized in the regional risk control of the park effectively.

  12. Evaluation and Selection of International Supplier, Underscoring Risk Factors

    Directory of Open Access Journals (Sweden)

    seyed Mohammad Ali Khatami Firouzabadi

    2014-05-01

    Full Text Available This paper evaluates the decision making process for import complete manufactured pieces versus import of partial pieces to assemble in Iran, taking into account the risk factors for a manufacturing company. Since this sort of decision making confront with several risks, it is necessary to establish a process for finding the risks associated with this kind of problems in order to decrease the effects of these risks in the process. Since the problem is classified as a Multiple Criteria Decision Making (MCDM problem, Uncertain Analytical Hierarchy Process (UAHP was used to find the most attractive alternative. Because the alternatives were identified from the first point, a bottom-up procedure was used to organize the hierarchy. In initial stage, the attributes which distinct from the alternatives were obtained by literature review and experts' interviews. Then the attributes were grouped to upper level to establish the criteria. Three criteria were found from this stage. The criteria were product, partners, and environment which they encompassed 12 attributes. Forming the hierarchy and doing the uncertain pairwised comparisons, which considers a range of numbers instead of one single number for declaring the preference between two factors, a Linear Programming (LP model with two types of objective functions were formed for each individual alternative. Each single LP model can express the maximum and minimum value of each individual alternative. The research's results indicate the most appropriate alternative is to import the final product from India. The last preferred one was to import the parts of the final product from India. This study can be a suitable framework in supply chain management and purchasing decisions and risk evaluations because the major parts of manufacturing activities is always to decide about the selection of most preferred strategies for companies.

  13. Maintenance evaluation using risk based criteria

    International Nuclear Information System (INIS)

    Torres Valle, A.

    1996-01-01

    The maintenance evaluation is currently performed by using economic and, in some case, technical equipment failure criteria, however this is done to a specific equipment level. In general, when statistics are used the analysis for maintenance optimization are made isolated and whit a post mortem character; The integration provided by mean of Probabilistic Safety assessment (PSA) together with the possibilities of its applications, allow for evaluation of maintenance on the basis of broader scope criteria in regard to those traditionally used. The evaluate maintenance using risk based criteria, is necessary to follow a dynamic and systematic approach, in studying the maintenance strategy, to allow for updating the initial probabilistic models, for including operational changes that often take place during operation of complex facilities. This paper proposes a dynamic evaluation system of maintenance task. The system is illustrated by means of a practical example

  14. Organization of Risk Analysis Codes for Living Evaluations (ORACLE)

    International Nuclear Information System (INIS)

    Batt, D.L.; MacDonald, P.E.; Sattison, M.B.; Vesely, E.

    1987-01-01

    ORACLE (Organization of Risk Analysis Codes for Living Evaluations) is an integration concept for using risk-based information in United States Nuclear Regulatory Commission (USNRC) applications. Portions of ORACLE are being developed at the Idaho Nationale Engineering Laboratory for the USNRC. The ORACLE concept consists of related databases, software, user interfaces, processes, and quality control checks allowing a wide variety of regulatory problems and activities to be addressed using current, updated PRA information. The ORACLE concept provides for smooth transitions between one code and the next without pre- or post-processing. (orig.)

  15. The role of risk perception in making flood risk management more effective

    Science.gov (United States)

    Buchecker, M.; Salvini, G.; Di Baldassarre, G.; Semenzin, E.; Maidl, E.; Marcomini, A.

    2013-11-01

    Over the last few decades, Europe has suffered from a number of severe flood events and, as a result, there has been a growing interest in probing alternative approaches to managing flood risk via prevention measures. A literature review reveals that, although in the last decades risk evaluation has been recognized as key element of risk management, and risk assessment methodologies (including risk analysis and evaluation) have been improved by including social, economic, cultural, historical and political conditions, the theoretical schemes are not yet applied in practice. One main reason for this shortcoming is that risk perception literature is mainly of universal and theoretical nature and cannot provide the necessary details to implement a comprehensive risk evaluation. This paper therefore aims to explore a procedure that allows the inclusion of stakeholders' perceptions of prevention measures in risk assessment. It proposes to adopt methods of risk communication (both one-way and two-way communication) in risk assessment with the final aim of making flood risk management more effective. The proposed procedure not only focuses on the effect of discursive risk communication on risk perception, and on achieving a shared assessment of the prevention alternatives, but also considers the effects of the communication process on perceived uncertainties, accepted risk levels, and trust in the managing institutions. The effectiveness of this combined procedure has been studied and illustrated using the example of the participatory flood prevention assessment process on the Sihl River in Zurich, Switzerland. The main findings of the case study suggest that the proposed procedure performed well, but that it needs some adaptations for it to be applicable in different contexts and to allow a (semi-) quantitative estimation of risk perception to be used as an indicator of adaptive capacity.

  16. Quantifying Cardiometabolic Risk Using Modifiable Non–Self-Reported Risk Factors

    Science.gov (United States)

    Marino, Miguel; Li, Yi; Pencina, Michael J.; D’Agostino, Ralph B.; Berkman, Lisa F.; Buxton, Orfeu M.

    2014-01-01

    Background Sensitive general cardiometabolic risk assessment tools of modifiable risk factors would be helpful and practical in a range of primary prevention interventions or for preventive health maintenance. Purpose To develop and validate a cumulative general cardiometabolic risk score that focuses on non–self-reported modifiable risk factors such as glycosylated hemoglobin (HbA1c) and BMI so as to be sensitive to small changes across a span of major modifiable risk factors, which may not individually cross clinical cut off points for risk categories. Methods We prospectively followed 2,359 cardiovascular disease (CVD)-free subjects from the Framingham offspring cohort over a 14–year follow-up. Baseline (fifth offspring examination cycle) included HbA1c and cholesterol measurements. Gender–specific Cox proportional hazards models were considered to evaluate the effects of non–self-reported modifiable risk factors (blood pressure, total cholesterol, high–density lipoprotein cholesterol, smoking, BMI, and HbA1c) on general CVD risk. We constructed 10–year general cardiometabolic risk score functions and evaluated its predictive performance in 2012–2013. Results HbA1c was significantly related to general CVD risk. The proposed cardiometabolic general CVD risk model showed good predictive performance as determined by cross-validated discrimination (male C-index=0.703, 95% CI=0.668, 0.734; female C-index=0.762, 95% CI=0.726, 0.801) and calibration (lack-of-fit χ2=9.05 [p=0.338] and 12.54 [p=0.128] for men and women, respectively). Conclusions This study presents a risk factor algorithm that provides a convenient and informative way to quantify cardiometabolic risk based on modifiable risk factors that can motivate an individual’s commitment to prevention and intervention. PMID:24951039

  17. Quantifying cardiometabolic risk using modifiable non-self-reported risk factors.

    Science.gov (United States)

    Marino, Miguel; Li, Yi; Pencina, Michael J; D'Agostino, Ralph B; Berkman, Lisa F; Buxton, Orfeu M

    2014-08-01

    Sensitive general cardiometabolic risk assessment tools of modifiable risk factors would be helpful and practical in a range of primary prevention interventions or for preventive health maintenance. To develop and validate a cumulative general cardiometabolic risk score that focuses on non-self-reported modifiable risk factors such as glycosylated hemoglobin (HbA1c) and BMI so as to be sensitive to small changes across a span of major modifiable risk factors, which may not individually cross clinical cut-off points for risk categories. We prospectively followed 2,359 cardiovascular disease (CVD)-free subjects from the Framingham offspring cohort over a 14-year follow-up. Baseline (fifth offspring examination cycle) included HbA1c and cholesterol measurements. Gender-specific Cox proportional hazards models were considered to evaluate the effects of non-self-reported modifiable risk factors (blood pressure, total cholesterol, high-density lipoprotein cholesterol, smoking, BMI, and HbA1c) on general CVD risk. We constructed 10-year general cardiometabolic risk score functions and evaluated its predictive performance in 2012-2013. HbA1c was significantly related to general CVD risk. The proposed cardiometabolic general CVD risk model showed good predictive performance as determined by cross-validated discrimination (male C-index=0.703, 95% CI=0.668, 0.734; female C-index=0.762, 95% CI=0.726, 0.801) and calibration (lack-of-fit chi-square=9.05 [p=0.338] and 12.54 [p=0.128] for men and women, respectively). This study presents a risk factor algorithm that provides a convenient and informative way to quantify cardiometabolic risk on the basis of modifiable risk factors that can motivate an individual's commitment to prevention and intervention. Copyright © 2014 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  18. Decision theory and the evaluation of risks and benefits of clinical trials.

    Science.gov (United States)

    Bernabe, Rosemarie D C; van Thiel, Ghislaine J M W; Raaijmakers, Jan A M; van Delden, Johannes J M

    2012-12-01

    Research ethics committees (RECs) are tasked to assess the risks and the benefits of a clinical trial. In previous studies, it was shown that RECs find this task difficult, if not impossible, to do. The current approaches to benefit-risk assessment (i.e. Component Analysis and the Net Risk Test) confound the various risk-benefit tasks, and as such, make balancing impossible. In this article, we show that decision theory, specifically through the expected utility theory and multiattribute utility theory, enable for an explicit and ethically weighted risk-benefit evaluation. This makes a balanced ethical justification possible, and thus a more rationally defensible decision making. Copyright © 2012 Elsevier Ltd. All rights reserved.

  19. Evaluation of the carcinogenic risks at the influence of POPs.

    Science.gov (United States)

    Nazhmetdinova, Aiman; Kassymbayev, Adlet; Chalginbayeva, Altinay

    2017-12-20

    Kazakhstan is included in the list of environmentally vulnerable countries and Kyzylorda oblast in particular. This is due to its geographical, spatial and temporal and socioeconomic features. As part of the program "Integrated approaches in the management of public health in the Aral region", we have carried out an expertise on many samples of natural environments and products. Samples were selected in accordance with sampling procedures according to regulatory documents by specialists of the Pesticide Toxicology Laboratory. It is accredited by the State Standard of the Republic of Kazakhstan, for compliance with ST RK ISO/IEC 17025-2007 "General requirements for the competence of test and calibration laboratories". Gas chromatograph was used for the determination of residues of organochlorine pesticides. For the determination of dioxins, polychlorinated biphenyl was conducted on the gas chromatomass spectrometer with quadruple detector produce by Agilent Company, USA. To assess the risk, we carried out the mathematical calculations according to the risk of chemicals polluting (No P 2.1.10.1920-04, Russia). Calculation of the carcinogenic risk was carried out with the use of data on the size of the exposure and meanings of carcinogenic potential factors (slope factor and unit risk). The evaluation of persistent organic pollutants (POPs), based on the previous results of the research concerning water, soil and food products, was held in five population settlements in Kyzylorda oblast villages: Ayteke bi, Zhalagash, Zhosaly, Shieli and Aralsk town. Pollution with the POPs in the environmental objects by means of exposition and evaluation of the carcinogenic risk to human health is confirmed by the data of the statistical reporting about some morbidity in Kyzylorda oblast, such as skin diseases and subcutaneous tissue, endocrine system diseases, pregnancy complications etc. The received levels of carcinogenic risks, which were first carried out in the Republic of

  20. Cardiovascular risk prediction

    DEFF Research Database (Denmark)

    Graversen, Peter; Abildstrøm, Steen Z.; Jespersen, Lasse

    2016-01-01

    Aim European society of cardiology (ESC) guidelines recommend that cardiovascular disease (CVD) risk stratification in asymptomatic individuals is based on the Systematic Coronary Risk Evaluation (SCORE) algorithm, which estimates individual 10-year risk of death from CVD. We assessed the potential...

  1. The radon in Corsica: evaluation of exposure and associated risks

    International Nuclear Information System (INIS)

    2006-02-01

    The average level found in Corsica is superior to that one found in France. On the basis of the results of it campaign I.R.S.N.-D.G.S., the French average is of 90 Bq.m 3 against 197 Bq.m 3 for Corsica. The risk of dying from a lung cancer attributable to the radon was estimated at 13 % in France. The evaluation of risk led on Corsica shows a risk attributable to the radon included between 21.5 and 28 %.This evaluation of risk is only a stage. It is important to arrest better the exposure to the radon of the Corsican population. For a good estimation of the levels of radon and thus the impact of this one, additional measures are necessary. The results of the data analysis of exposure allow to guide the choice of the new measures: a campaign on the season effect in Corsica and a completion of the measures in housing are two main axes.Seen the importance of the interaction between the tobacco and the radon, a good estimation of the tobacco customs in Corsica and its evolution in the time seems essential to estimate indeed the impact of the radon in this region. (N.C.)

  2. Legacy Risk Measure for Environmental Waste

    International Nuclear Information System (INIS)

    Eide, S. A.; Nitschke, R. L.

    2002-01-01

    The Idaho National Engineering and Environmental Laboratory (INEEL) is investigating the development of a comprehensive and quantitative risk model framework for environmental management activities at the site. Included are waste management programs (high-level waste, transuranic waste, low-level waste, mixed low-level waste, spent nuclear fuel, and special nuclear materials), major environmental restoration efforts, major decontamination and decommissioning projects, and planned long-term stewardship activities. Two basic types of risk estimates are included: risks from environmental management activities, and long-term legacy risks from wastes/materials. Both types of risks are estimated using the Environment, Safety, and Health Risk Assessment Program (ESHRAP) developed at the INEEL. Given these two types of risk calculations, the following evaluations can be performed: risk evaluation of an entire program (covering waste/material as it now exists through disposal or other e nd states); risk comparisons of alternative programs or activities; comparisons of risk benefit versus risk cost for activities or entire programs; ranking of programs or activities by risk; ranking of wastes/materials by risk; evaluation of site risk changes with time as activities progress; and integrated performance measurement using indicators such as injury/death and exposure rates. This paper discusses the definition and calculation of legacy risk measures and associated issues. The legacy risk measure is needed to support three of the seven types of evaluations listed above: comparisons of risk benefit versus risk cost, ranking of wastes/materials by risk, and evaluation of site risk changes with time

  3. A new perspective on Renn and Klinke's approach to risk evaluation and management

    International Nuclear Information System (INIS)

    Kristensen, V.; Aven, T.; Ford, D.

    2006-01-01

    In this paper we discuss Renn and Klinke's approach for risk evaluation and selection of risk management strategies. The main focus in the discussion is the foundational basis and the understanding of what risk is, and how a different foundational basis may simplify and improve the characterization of risk. We will present and discuss an alternative set of characteristics, and give some recommendations with respect to selection of risk management strategies based on different values or magnitudes of these characteristics. We believe that the main focus when describing and managing risk should be the potential consequences, represented by observable quantities, and the uncertainty related to their future values

  4. A semi-quantitative model for risk appreciation and risk weighing

    DEFF Research Database (Denmark)

    Bos, Peter M.J.; Boon, Polly E.; van der Voet, Hilko

    2009-01-01

    Risk managers need detailed information on (1) the type of effect, (2) the size (severity) of the expected effect(s) and (3) the fraction of the population at risk to decide on well-balanced risk reduction measures. A previously developed integrated probabilistic risk assessment (IPRA) model...... provides quantitative information on these three parameters. A semi-quantitative tool is presented that combines information on these parameters into easy-readable charts that will facilitate risk evaluations of exposure situations and decisions on risk reduction measures. This tool is based on a concept...... detailed information on the estimated health impact in a given exposure situation. These graphs will facilitate the discussions on appropriate risk reduction measures to be taken....

  5. Risk evaluation of remedial alternatives for the Hanford Site

    International Nuclear Information System (INIS)

    1994-09-01

    This document provides guidance on the process of risk evaluation of remedial alternatives (RERA) at the Hanford Site. Remediation activities at the Hanford Site are being conducted pursuant to the Comprehensive Environmental Restoration, Compensation, and Liability Act and the Resource Conservation and Recovery Act. This document identifies points in the remedial alternative selection process where risk assessment input is either required or desirable. For each of these points of application, the document identifies issues to consider and address, and suggests possible approaches, techniques, and appropriate levels of detail. The level of detail of a RERA is driven by the need to use risk as a criterion for selecting a remedial alternative. Such a document is needed to ensure that RERA is conducted in a consistent manner, and to prevent restating or creating guidance within each RERA

  6. Pressure Ulcer Risk Evaluation in Critical Patients: Clinical and Social Characteristics.

    Science.gov (United States)

    de Azevedo Macena, Mônica Suêla; da Costa Silva, Rayanne Suely; Dias Fernandes, Maria Isabel Da Conceição; de Almeida Medeiros, Ana Beatriz; Batista Lúcio, Kadyjina Daiane; de Carvalho Lira, Ana Luisa Brandão

    2017-01-01

    Pressure ulcers increase hospital stays and treatment costs due to their complications. Therefore, recognizing factors that contribute to pressure ulcer risk are important to patient safety. To evaluate the association between the scores of the Waterlow, Braden, and Norton scales and clinical and social characteristics in critically ill patients. A cross-sectional study of 78 patients in an adult intensive care unit of a university hospital in Northeastern Brazil was conducted from July to December 2015. Data included social and clinical information and the risk factors of the Braden, Norton and Waterlow scales. Data were analysed by the descriptive and inferential statistics. Most of the participants were female, adults and elderly people with brown skin colour, low education levels and insufficient income. Most of them showed a high risk for developing pressure ulcers using the three evaluated scales. Age, smoking status, diabetes and hypertension were associated with scores on the Waterlow, Braden and Norton scales. Age, use of the tobacco, diabetes and hypertension were associated with the risk of pressure ulcers in ICU patients.

  7. Risk Evaluation for CO2 Geosequestration in the Knox Supergroup, Illinois Basin Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Hnottavange-Telleen, Ken; Leetaru, Hannes

    2014-09-30

    This report describes a process and provides seed information for identifying and evaluating risks pertinent to a hypothetical carbon dioxide (CO2) capture and sequestration (CCS) project. In the envisioned project, the target sequestration reservoir rock is the Potosi Formation of the Knox Supergroup. The Potosi is identified as a potential target formation because (1) at least locally, it contains vuggy to cavernous layers that have very high porosity, and (2) it is present in areas where the deeper Mt. Simon Sandstone (a known potential reservoir unit) is absent or nonporous. The key report content is discussed in Section 3.3, which describes two lists of Features, Events, and Processes (FEPs) that should be considered during the design stage of such a project. These lists primarily highlight risk elements particular to the establishment of the Potosi as the target formation in general. The lists are consciously incomplete with respect to risk elements that would be relevant for essentially all CCS projects regardless of location or geology. In addition, other risk elements specific to a particular future project site would have to be identified. Sources for the FEPs and scenarios listed here include the iconic Quintessa FEPs list developed for the International Energy Agency Greenhouse Gas (IEAGHG) Programme; previous risk evaluation projects executed by Schlumberger Carbon Services; and new input solicited from experts currently working on aspects of CCS in the Knox geology. The projects used as sources of risk information are primarily those that have targeted carbonate reservoir rocks similar in age, stratigraphy, and mineralogy to the Knox-Potosi. Risks of using the Potosi Formation as the target sequestration reservoir for a CCS project include uncertainties about the levels of porosity and permeability of that rock unit; the lateral consistency and continuity of those properties; and the ability of the project team to identify suitable (i.e., persistently

  8. Designs for Risk Evaluation and Management

    Energy Technology Data Exchange (ETDEWEB)

    2015-12-01

    The Designs for Risk Evaluation and Management (DREAM) tool was developed as part of the effort to quantify the risk of geologic storage of carbon dioxide (CO2) under the U.S. Department of Energy's National Risk Assessment Partnership (NRAP). DREAM is an optimization tool created to identify optimal monitoring schemes that minimize the time to first detection of CO2 leakage from a subsurface storage formation. DREAM acts as a post-processer on user-provided output from subsurface leakage simulations. While DREAM was developed for CO2 leakage scenarios, it is applicable to any subsurface leakage simulation of the same output format. The DREAM tool is comprised of three main components: (1) a Java wizard used to configure and execute the simulations, (2) a visualization tool to view the domain space and optimization results, and (3) a plotting tool used to analyze the results. A secondary Java application is provided to aid users in converting common American Standard Code for Information Interchange (ASCII) output data to the standard DREAM hierarchical data format (HDF5). DREAM employs a simulated annealing approach that searches the solution space by iteratively mutating potential monitoring schemes built of various configurations of monitoring locations and leak detection parameters. This approach has proven to be orders of magnitude faster than an exhaustive search of the entire solution space. The user's manual illustrates the program graphical user interface (GUI), describes the tool inputs, and includes an example application.

  9. Evaluation of Risk Versus Benefit Information in Direct-To-Consumer (DTC) Prescription Drug Television Advertisements.

    Science.gov (United States)

    Fahim, Germin; Toscani, Michael; Barone, Joseph A; Wang, Chris; Gandhi, Shivani

    2018-01-01

    The FDA's Presenting Risk Information draft guidance from May 2009 states that the time of risk versus benefit is a factor taken into consideration when evaluating audio and video direct-to-consumer (DTC) broadcasts. The objective of the study is to evaluate the proportion of risk narration on television (TV) advertisements in comparison to the actual proportion of serious adverse effects findings across select therapeutic areas. The study reviews prescription drug TV advertisements between the years 2010 and 2015 separated by therapeutic class. Indicators to assess risk versus benefit are as follows: total benefit time, total risk time, total ad time, percentage proportion of risk, and number of serious adverse effects (SAEs) listed in the package insert. The objective is establishing proportion of risk-to-benefit narration across therapeutic areas and the proportion of risk narration compared to the number of SAEs in the package insert. These outcomes will reflect whether TV advertisements abide by the "fair balance" rule and if the time spent on risk narrations is proportional to the number of SAEs across therapeutic areas. An analysis of risk versus benefit showed that there was a vast range of percentage differences in risk versus benefit narration across the products selected. The majority of the products narrated showed a 40% to 60% risk-to-benefit ratio. Six out of the 10 products evaluated communicated applicable black box warnings. There was variability among the SAE percentages presented between products. Lack of consistency exists between risks versus benefit proportions among different drug products.

  10. Catastrophe risk data scoping for disaster risk finance in Asia

    Science.gov (United States)

    Millinship, Ian; Revilla-Romero, Beatriz

    2017-04-01

    Developing countries across Latin America, Africa, and Asia are some of the most exposed to natural catastrophes in the world. Over the last 20 years, Asia has borne almost half the estimated global economic cost of natural disasters - around 53billion annually. Losses from natural disasters can damage growth and hamper economic development and unlike in developed countries where risk is reallocated through re/insurance, typically these countries rely on budget reallocations and donor assistance in order to attempt to meet financing needs. There is currently an active international dialogue on the need to increase access to disaster risk financing solutions in Asia. The World Bank-GFDRR Disaster Risk Financing and Insurance Program with financial support from the Rockefeller Foundation, is currently working to develop regional options for disaster risk financing for developing countries in Asia. The first stage of this process has been to evaluate available catastrophe data suitable to support the design and implementation of disaster risk financing mechanisms in selected Asian countries. This project was carried out by a consortium of JBA Risk Management, JBA Consulting, ImageCat and Cat Risk Intelligence. The project focuses on investigating potential data sources for fourteen selected countries in Asia, for flood, tropical cyclone, earthquake and drought perils. The project was carried out under four stages. The first phase focused to identify and catalogue live/dynamic hazard data sources such as hazard gauging networks, or earth observations datasets which could be used to inform a parametric trigger. Live data sources were identified that provide credibility, transparency, independence, frequent reporting, consistency and stability. Data were catalogued at regional level, and prioritised at local level for five countries: Bangladesh, Indonesia, Pakistan, Sri Lanka and Viet Nam. The second phase was to identify, catalogue and evaluate catastrophe risk models

  11. Risk evaluation and mitigation strategies (REMS): educating the prescriber.

    Science.gov (United States)

    Nicholson, Susan C; Peterson, Janet; Yektashenas, Behin

    2012-02-01

    The US FDA Amendments Act of 2007 was signed into law on 27 September 2007. A provision of this law granted the FDA new powers to enhance drug safety by requiring the pharmaceutical industry to develop Risk Evaluation and Mitigation Strategies (REMS). REMS are deemed necessary when a question exists as to whether the benefits of a drug outweigh its risks. REMS constitute a safety plan with several potential components, including a medication guide, a communication plan, elements to ensure safe use and an implementation system to help guide the prescribers, pharmacists and patients. This applies to existing drugs on the market, new drug applications (NDAs), abbreviated NDAs (generics) and biologics licence applications. REMS represent an 'upgrade' from previously required risk minimization action plans, based on the strengthening of FDA powers of authority and enforceability to incur monetary penalties against individuals representing the pharmaceutical industry who fail to comply. For illustrative purposes, we chose the drug romiplostim (Nplate®) to present an REMS, as all components were utilized to help assuage risks associated with the drug. Romiplostim is an FDA-approved drug used to treat thrombocytopenia in patients with chronic immune (idiopathic) thrombocytopenic purpura that has a significant adverse safety profile based on the risk of changes in bone marrow reticulin formation and bone marrow fibroses, and other associated risks. This review of current REMS policy is intended to provide the prescriber with a better understanding of current modalities in FDA-mandated drug safety programmes, which will impact day-to-day healthcare provider practices.

  12. Risk perception, risk evaluation and human values: cognitive bases of acceptability of a radioactive waste repository

    International Nuclear Information System (INIS)

    Earle, T.C.; Lindell, M.K.; Rankin, W.L.

    1981-07-01

    Public acceptance of radioactive waste management alternatives depends in part on public perception of the associated risks. Three aspects of those perceived risks were explored in this study: (1) synthetic measures of risk perception based on judgments of probability and consequences; (2) acceptability of hypothetical radioactive waste policies, and (3) effects of human values on risk perception. Both the work on synthetic measures of risk perception and on the acceptability of hypothetical policies included investigations of three categories of risk: (1) Short-term public risk (affecting persons living when the wastes are created), (2) Long-term public risk (affecting persons living after the time the wastes were created), and (3) Occupational risk (affecting persons working with the radioactive wastes). The human values work related to public risk perception in general, across categories of persons affected

  13. Rape Prevention with College Men: Evaluating Risk Status

    Science.gov (United States)

    Stephens, Kari A.; George, William H.

    2009-01-01

    This study evaluates the effectiveness of a theoretically based rape prevention intervention with college men who were at high or low risk to perpetrate sexually coercive behavior. Participants (N = 146) are randomly assigned to the intervention or control group. Outcomes include rape myth acceptance, victim empathy, attraction to sexual…

  14. Evaluation of risk scores for risk stratification of acute coronary syndromes in the Myocardial Infarction National Audit Project (MINAP) database.

    Science.gov (United States)

    Gale, C P; Manda, S O M; Weston, C F; Birkhead, J S; Batin, P D; Hall, A S

    2009-03-01

    To compare the discriminative performance of the PURSUIT, GUSTO-1, GRACE, SRI and EMMACE risk models, assess their performance among risk supergroups and evaluate the EMMACE risk model over the wider spectrum of acute coronary syndrome (ACS). Observational study of a national registry. All acute hospitals in England and Wales. 100 686 cases of ACS between 2003 and 2005. Model performance (C-index) in predicting the likelihood of death over the time period for which they were designed. The C-index, or area under the receiver-operating curve, range 0-1, is a measure of the discriminative performance of a model. The C-indexes were: PURSUIT C-index 0.79 (95% confidence interval 0.78 to 0.80); GUSTO-1 0.80 (0.79 to 0.81); GRACE in-hospital 0.80 (0.80 to 0.81); GRACE 6-month 0.80 (0.79 to 0.80); SRI 0.79 (0.78 to 0.80); and EMMACE 0.78 (0.77 to 0.78). EMMACE maintained its ability to discriminate 30-day mortality throughout different ACS diagnoses. Recalibration of the model offered no notable improvement in performance over the original risk equation. For all models the discriminative performance was reduced in patients with diabetes, chronic renal failure or angina. The five ACS risk models maintained their discriminative performance in a large unselected English and Welsh ACS population, but performed less well in higher-risk supergroups. Simpler risk models had comparable performance to more complex risk models. The EMMACE risk score performed well across the wider spectrum of ACS diagnoses.

  15. First Evaluation of a Contingency Management Intervention Addressing Adolescent Substance Use and Sexual Risk Behaviors: Risk Reduction Therapy for Adolescents.

    Science.gov (United States)

    Letourneau, Elizabeth J; McCart, Michael R; Sheidow, Ashli J; Mauro, Pia M

    2017-01-01

    There is a need for interventions that comprehensively address youth substance use disorders (SUD) and sexual risk behaviors. Risk Reduction Therapy for Adolescents (RRTA) adapts a validated family-focused intervention for youth SUD to include sexual risk reduction components in a single intervention. In this first evaluation of RRTA, drug court involved youth were randomly assigned to RRTA (N=45) or usual services (US; N=60) and followed through 12-months post-baseline. RRTA included weekly cognitive behavior therapy and behavior management training and contingency-contracting with a point earning system managed by caregivers targeting drug use and sexual risk antecedents. Longitudinal models estimated within-group change and between-group differences through 6- and 12-month follow-up on outcomes for substance use, sexual risk behaviors, and protective HIV behaviors. Robust effects of the intervention were not detected under conditions of the study that included potent background interventions by the juvenile drug court. Considerations about future development and testing of sexual risk reduction therapy for youth are discussed, including the potential role of contingency management in future interventions. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Study on the evaluation system for the coal safety management based on risk pre-control

    Institute of Scientific and Technical Information of China (English)

    LI Xin-chun; XU Hai-xia; WANG Pei; SONG Xue-feng

    2009-01-01

    The new type of risk management is process management.First,the hazard sources are identified before coal mine accidents occur,and then the pre-control measure and information monitoring method based on classifying the hidden hazard sources are given.Lastly,the risk pre-alarm and risk control method are confirmed,the management standard and management measure are used to eliminate the hidden hazard sources.In this study,an evaluation system is built to evaluate the result of risk management.

  17. Seismic risk evaluation for high voltage air insulated substations

    International Nuclear Information System (INIS)

    Camensig, Carlo; Bresesti, Luca; Clementel, Stefano; Salvetti, Maurizio

    1997-01-01

    This paper describes the results of the analytical and experimental activities performed by ISMES for the evaluation of the structural reliability of electrical substations with respect to seismic events. In the following, the reference station is described along with the methods used to define the site seismic input, the analytical and experimental evaluation of the components' fragility curves and the whole station seismic risk evaluation

  18. Risk perception, risk evaluation and human values: cognitive bases of acceptability of a radioactive waste repository

    Energy Technology Data Exchange (ETDEWEB)

    Earle, T.C.; Lindell, M.K.; Rankin, W.L.

    1981-07-01

    Public acceptance of radioactive waste management alternatives depends in part on public perception of the associated risks. Three aspects of those perceived risks were explored in this study: (1) synthetic measures of risk perception based on judgments of probability and consequences; (2) acceptability of hypothetical radioactive waste policies, and (3) effects of human values on risk perception. Both the work on synthetic measures of risk perception and on the acceptability of hypothetical policies included investigations of three categories of risk: (1) Short-term public risk (affecting persons living when the wastes are created), (2) Long-term public risk (affecting persons living after the time the wastes were created), and (3) Occupational risk (affecting persons working with the radioactive wastes). The human values work related to public risk perception in general, across categories of persons affected. Respondents were selected according to a purposive sampling strategy.

  19. Intuitive risk perception: research results of attitude surveys toward risk and technology

    International Nuclear Information System (INIS)

    Renn, O.; Peters, H.P.

    1982-01-01

    Using the instruments of the empirical social sciences, a cross-section study was conducted comprising experiments on qualitative risk characteristics, in-depth interviews on mechanisms of risk perception and representative surveys of the public on technical risk sources, in particular with regard to nuclear energy. The results of these studies show that person-related expectations in respect of risk consequences, the possibility of personal influencing control, the severity of risk consequences and one's own risk propensity play a significant role in the evaluation of risks

  20. Risk evaluation in Dutch land-use planning

    NARCIS (Netherlands)

    Xanten, van N.H.W.; Pietersen, C.M.; Pasman, H.J.; Torn, van der P.; Vrijling, H.K.; Wal, van der A.J.; Kerstens, J.G.M.

    2014-01-01

    In Dutch external safety policy, the acceptance of risk for the population in areas surrounding hazardous substances establishments is based on a limit value for individual risk (IR). Additionally, changes to societal risk (SR) must be justified. A specific software program (SAFETI-NL) with the

  1. Risk assessment and risk management of mycotoxins.

    Science.gov (United States)

    2012-01-01

    Risk assessment is the process of quantifying the magnitude and exposure, or probability, of a harmful effect to individuals or populations from certain agents or activities. Here, we summarize the four steps of risk assessment: hazard identification, dose-response assessment, exposure assessment, and risk characterization. Risk assessments using these principles have been conducted on the major mycotoxins (aflatoxins, fumonisins, ochratoxin A, deoxynivalenol, and zearalenone) by various regulatory agencies for the purpose of setting food safety guidelines. We critically evaluate the impact of these risk assessment parameters on the estimated global burden of the associated diseases as well as the impact of regulatory measures on food supply and international trade. Apart from the well-established risk posed by aflatoxins, many uncertainties still exist about risk assessments for the other major mycotoxins, often reflecting a lack of epidemiological data. Differences exist in the risk management strategies and in the ways different governments impose regulations and technologies to reduce levels of mycotoxins in the food-chain. Regulatory measures have very little impact on remote rural and subsistence farming communities in developing countries, in contrast to developed countries, where regulations are strictly enforced to reduce and/or remove mycotoxin contamination. However, in the absence of the relevant technologies or the necessary infrastructure, we highlight simple intervention practices to reduce mycotoxin contamination in the field and/or prevent mycotoxin formation during storage.

  2. Ratio K: a New Way of Metering and Evaluating the Risk and Return of Stock Investment

    Institute of Scientific and Technical Information of China (English)

    朱淑珍; 朱静怡

    2003-01-01

    Although widely used, both the Markowitz model and VAR (Value at Risk) model have some limitations in evaluating the risk and return of stock investnent.By the analysis of the conceptions of risk and return,together with the three hypotheses of technological analysis, a novelty model of metering and evaluating the risk and return of stock investnent is established.The major indicator of this model , risk-return ratio K, combines the characteristic indicators of risk and return. Regardless of the form of the risk-return probability density functions, this indicator K can always reflect the risk-return performances of the invested stocks clearly and accurately. How to use the model to make optimum investment and how to make portfolio combined with clustering analysis is also explained.

  3. Evaluation of severe accident risks and the potential for risk reduction: Grand Gulf, Unit 1. Draft for comment, February 1987

    Energy Technology Data Exchange (ETDEWEB)

    Amos, C N [Technadyne Engineering Consultants, Inc., Albuquerque, NM (United States); Benjamin, A S; Kunsman, D M; Williams, D C [Sandia National Laboratories, Albuquerque, NM (United States); Boyd, G J; Lewis, S R [Safety and Reliability Optimization Services, Inc., Knoxville, TN (United States); Smith, L N [Science Applications International Corporation, Albuquerque, NM (United States)

    1987-04-01

    The Severe Accident Risk Reduction Program (SARRP) has completed a rebaselining of the risks to the public from a boiling water reactor with a Mark III containment (Grand Gulf, Unit 1). Emphasis was placed on determining the magnitude and character of the uncertainties, rather than focusing on a point estimate. The risk-reduction potential of a set of proposed safety option backfits was also studied, and their costs and benefits were also evaluated. It was found that the risks from internal events are generally low relative to previous studies; for example, most of the uncertainty range is lower than the point estimate of risk for the Peach Bottom plant in the Reactor Safety Study (RSS). However, certain unresolved issues cause the top of the uncertainty band to appear at a level that is comparable with the RSS point estimate. These issues include the diesel generator failure rate, iodine and cesium revolatilization after vessel breach and the possibility of reactor vessel pedestal failure caused by core debris attack. Some of the postulated safety options appear to be potentially cost effective for the Grand Gulf power plant, particularly when onsite accidents costs are included in the evaluation of benefits. Principally these include procedural modifications and relatively inexpensive hardware additions to insure core cooling in the event of a station blackout. This work supports the Nuclear Regulatory Commission's assessment of severe accidents in NUREG-1150. (author)

  4. Development of a relative risk model for evaluating ecological risk of water environment in the Haihe River Basin estuary area.

    Science.gov (United States)

    Chen, Qiuying; Liu, Jingling; Ho, Kin Chung; Yang, Zhifeng

    2012-03-15

    Ecological risk assessment for water environment is significant to water resource management of basin. Effective environmental management and systems restoration such as the Haihe River Basin require holistic understanding of the relative importance of various stressor-related impacts throughout the basin. As an effective technical tool for evaluating the ecological risk, relative risk model (RRM) was applied in regional scale successfully. In this study, the risk transfer from upstream of basin was considered and the RRM was developed through introducing the source-stressor-habitat exposure filter (SSH), the endpoint-habitat exposure filter (EH) and the stressor-endpoint effect filter (SE) to reflect the meaning of exposure and effect more explicit. Water environment which includes water quality, water quantity and aquatic ecosystems was selected as the assessment endpoints. We created a conceptual model which depicting potential and effect pathways from source to stressor to habitat to endpoint. The Haihe River Basin estuary (HRBE) was selected as the model case. The results showed that there were two low risk regions, one medium risk region and two high risk regions in the HRBE. The results also indicated that urbanization was the biggest source, the second was shipping and the third was industry, their risk scores are 5.65, 4.71 and 3.68 respectively. Furthermore, habitat destruction was the largest stressor with the risk scores (2.66), the second was oxygen consuming organic pollutants (1.75) and the third was pathogens (1.75). So these three stressors were the main influencing factors of the ecological pressure in the study area. For habitats, open waters (9.59) and intertidal mudflat were enduring the bigger pressure and should be taken considerable attention. Ecological service values damaged (30.54) and biodiversity decreased were facing the biggest risk pressure. Copyright © 2011 Elsevier B.V. All rights reserved.

  5. Risk assessment

    International Nuclear Information System (INIS)

    Kinchin, G.H.

    1983-01-01

    After defining risk and introducing the concept of individual and societal risk, the author considers each of these, restricting considerations to risk of death. Some probabilities of death arising from various causes are quoted, and attention drawn to the care necessary in making comparisons between sets of data and to the distinction between voluntary and involuntary categories and between early and delayed deaths. The presentation of information on societal risk is discussed and examples given. The history of quantified risk assessment is outlined, particularly related to the nuclear industry, the process of assessing risk discussed: identification of hazard causes, the development of accident chains and the use of event trees, the evaluation of probability through the collection of data and their use with fault trees, and the assessment of consequences of hazards in terms of fatalities. Reference is made to the human element and common-made failures, and to studies supporting the development of reliability assessment techniques. Acceptance criteria are discussed for individual and societal risk in the nuclear field, and it is shown that proposed criteria lead to risks conservative by comparison with risks from day-to-day accidents and other potentially hazardous industries. (U.K.)

  6. Flood Risk and Flood hazard maps - Visualisation of hydrological risks

    International Nuclear Information System (INIS)

    Spachinger, Karl; Dorner, Wolfgang; Metzka, Rudolf; Serrhini, Kamal; Fuchs, Sven

    2008-01-01

    Hydrological models are an important basis of flood forecasting and early warning systems. They provide significant data on hydrological risks. In combination with other modelling techniques, such as hydrodynamic models, they can be used to assess the extent and impact of hydrological events. The new European Flood Directive forces all member states to evaluate flood risk on a catchment scale, to compile maps of flood hazard and flood risk for prone areas, and to inform on a local level about these risks. Flood hazard and flood risk maps are important tools to communicate flood risk to different target groups. They provide compiled information to relevant public bodies such as water management authorities, municipalities, or civil protection agencies, but also to the broader public. For almost each section of a river basin, run-off and water levels can be defined based on the likelihood of annual recurrence, using a combination of hydrological and hydrodynamic models, supplemented by an analysis of historical records and mappings. In combination with data related to the vulnerability of a region risk maps can be derived. The project RISKCATCH addressed these issues of hydrological risk and vulnerability assessment focusing on the flood risk management process. Flood hazard maps and flood risk maps were compiled for Austrian and German test sites taking into account existing national and international guidelines. These maps were evaluated by eye-tracking using experimental graphic semiology. Sets of small-scale as well as large-scale risk maps were presented to test persons in order to (1) study reading behaviour as well as understanding and (2) deduce the most attractive components that are essential for target-oriented risk communication. A cognitive survey asking for negative and positive aspects and complexity of each single map complemented the experimental graphic semiology. The results indicate how risk maps can be improved to fit the needs of different user

  7. Methods of risk assessment

    International Nuclear Information System (INIS)

    Jones, D.R.

    1981-01-01

    The subject is discussed under the headings: introduction (identification, quantification of risk); some approaches to risk evaluation (use of the 'no risk' principle; the 'acceptable risk' method; risk balancing; comparison of risks, benefits and other costs); cost benefit analysis; an alternative approach (tabulation and display; description and reduction of the data table); identification of potential decision sets consistent with the constraints. Some references are made to nuclear power. (U.K.)

  8. Risk management and energy systems

    International Nuclear Information System (INIS)

    Carlevaro, F.; Romerio, F.

    1992-01-01

    In five sessions the following topics were dealt with: risk problems, risk analysis and evaluation tools, risks in industrial societies, risks of energy production, technological risks, ethics and political-social consensus. figs., tabs., refs

  9. Cumulative Risk Assessment (CRA): transforming the way we assess health risks.

    Science.gov (United States)

    Williams, Pamela R D; Dotson, G Scott; Maier, Andrew

    2012-10-16

    Human health risk assessments continue to evolve and now focus on the need for cumulative risk assessment (CRA). CRA involves assessing the combined risk from coexposure to multiple chemical and nonchemical stressors for varying health effects. CRAs are broader in scope than traditional chemical risk assessments because they allow for a more comprehensive evaluation of the interaction between different stressors and their combined impact on human health. Future directions of CRA include greater emphasis on local-level community-based assessments; integrating environmental, occupational, community, and individual risk factors; and identifying and implementing common frameworks and risk metrics for incorporating multiple stressors.

  10. Evaluation of a risk index for advanced proximal neoplasia of the colon.

    Science.gov (United States)

    Ruco, Arlinda; Stock, David; Hilsden, Robert J; McGregor, S Elizabeth; Paszat, Lawrence F; Saskin, Refik; Rabeneck, Linda

    2015-01-01

    A clinical risk index that uses distal colorectal findings at flexible sigmoidoscopy (FS) in conjunction with easily determined risk factors for advanced proximal neoplasia (APN) may be useful for tailoring or prioritizing screening with colonoscopy. To conduct an external evaluation of a previously published risk index in a large, well-characterized cohort. Cross-sectional. Teaching hospital and colorectal cancer screening center. A total of 5139 asymptomatic persons aged 50 to 74 (54.9% women) with a mean age (±SD) of 58.3 (±6.2) years. Between 2003 and 2011, all participants underwent a complete screening colonoscopy and removal of all polyps. Participants were classified as low, intermediate, or high risk for APN, based on their composite risk index scores. The concordance or c-statistic was used to measure discriminating ability of the risk index. A total of 167 persons (3.2%) had APN. The prevalence of those with APN among low-, intermediate-, and high-risk categories was 2.1%, 2.9%, and 6.5%, respectively. High-risk individuals were 3.2 times more likely to have APN compared with those in the low-risk category. The index did not discriminate well between those in the low- and intermediate-risk categories. The c-statistic for the overall index was 0.62 (95% confidence interval, 0.58-0.66). Distal colorectal findings were derived from colonoscopies and not FS itself. The risk index discriminated between those at low risk and those at high risk, but it had limited ability to discriminate between low- and intermediate-risk categories for prevalent APN. Information on other risk factors may be needed to tailor, or prioritize, access to screening colonoscopy. Copyright © 2015 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

  11. Comparative evaluation of risks at regional level

    International Nuclear Information System (INIS)

    Aigueperse, J.; Anguenot, F.; Hardy, S.

    1990-01-01

    In this paper we give the risks for the population of the South-East part of France. The risks are given, in case of chronic intake for energy production (coal and uranium mines, oil refineries, electricity production), for natural and medical irradiation (X-ray radiography-radiotherapy) and for domestic risks (use of chemical products). In case of accidents, the risks are studied in the optic of territorial gestion: transport of dangerous products (natural gas-fuel-chemical products) fires or explosions in chemical manufactories, water pollution by manufactories and agricultural uses [fr

  12. Societal Risk Evaluation Scheme (SRES: Scenario-Based Multi-Criteria Evaluation of Synthetic Biology Applications.

    Directory of Open Access Journals (Sweden)

    Christopher L Cummings

    Full Text Available Synthetic biology (SB applies engineering principles to biology for the construction of novel biological systems designed for useful purposes. From an oversight perspective, SB products come with significant uncertainty. Yet there is a need to anticipate and prepare for SB applications before deployment. This study develops a Societal Risk Evaluation Scheme (SRES in order to advance methods for anticipatory governance of emerging technologies such as SB. The SRES is based upon societal risk factors that were identified as important through a policy Delphi study. These factors range from those associated with traditional risk assessment, such as health and environmental consequences, to broader features of risk such as those associated with reversibility, manageability, anticipated levels of public concern, and uncertainty. A multi-disciplinary panel with diverse perspectives and affiliations assessed four case studies of SB using the SRES. Rankings of the SRES components are compared within and across the case studies. From these comparisons, we found levels of controllability and familiarity associated with the cases to be important for overall SRES rankings. From a theoretical standpoint, this study illustrates the applicability of the psychometric paradigm to evaluating SB cases. In addition, our paper describes how the SRES can be incorporated into anticipatory governance models as a screening tool to prioritize research, information collection, and dialogue in the face of the limited capacity of governance systems. To our knowledge, this is the first study to elicit data on specific cases of SB with the goal of developing theory and tools for risk governance.

  13. Probabilistic risk assessment methodology for risk management and regulatory applications

    International Nuclear Information System (INIS)

    See Meng Wong; Kelly, D.L.; Riley, J.E.

    1997-01-01

    This paper discusses the development and potential applications of PRA methodology for risk management and regulatory applications in the U.S. nuclear industry. The new PRA methodology centers on the development of This paper discusses the time-dependent configuration risk profile for evaluating the effectiveness of operational risk management programs at U.S. nuclear power plants. Configuration-risk profiles have been used as risk-information tools for (1) a better understanding of the impact of daily operational activities on plant safety, and (2) proactive planning of operational activities to manage risk. Trial applications of the methodology were undertaken to demonstrate that configuration-risk profiles can be developed routinely, and can be useful for various industry and regulatory applications. Lessons learned include a better understanding of the issues and characteristics of PRA models available to industry, and identifying the attributes and pitfalls in the developement of risk profiles

  14. Evaluation of different hedging strategies for commodity price risks of industrial cogeneration plants

    International Nuclear Information System (INIS)

    Palzer, Andreas; Westner, Günther; Madlener, Reinhard

    2013-01-01

    In this paper, we design and evaluate eight different strategies for hedging commodity price risks of industrial cogeneration plants. Price developments are parameterized based on EEX data from 2008 to 2011. The probability distributions derived are used to determine the value-at-risk (VaR) of the individual strategies, which are in a final step combined in a mean-variance portfolio analysis for determining the most efficient hedging strategy. We find that the strategy adopted can have a marked influence on the remaining price risk. Quarter futures are found to be particularly well suited for reducing market price risk. In contrast, spot trading of CO 2 certificates is found to be preferable compared to forward market trading. Finally, portfolio optimization shows that a mix of various hedging strategies can further improve the profitability of a heat-based cogeneration plant. - Highlights: • Evaluation of commodity price risk hedging strategies for industrial cogeneration. • Value-at-risk analysis of eight different hedging strategies. • Mean-variance portfolio analysis for determining the optimal hedging strategy mix. • A mix of hedging strategies further improves profitability of heat-based CHP

  15. Background risk information to assist in risk management decision making

    International Nuclear Information System (INIS)

    Hammonds, J.S.; Hoffman, F.O.; White, R.K.; Miller, D.B.

    1992-10-01

    The evaluation of the need for remedial activities at hazardous waste sites requires quantification of risks of adverse health effects to humans and the ecosystem resulting from the presence of chemical and radioactive substances at these sites. The health risks from exposure to these substances are in addition to risks encountered because of the virtually unavoidable exposure to naturally occurring chemicals and radioactive materials that are present in air, water, soil, building materials, and food products. To provide a frame of reference for interpreting risks quantified for hazardous waste sites, it is useful to identify the relative magnitude of risks of both a voluntary and involuntary nature that are ubiquitous throughout east Tennessee. In addition to discussing risks from the ubiquitous presence of background carcinogens in the east Tennessee environment, this report also presents risks resulting from common, everyday activities. Such information should, not be used to discount or trivialize risks from hazardous waste contamination, but rather, to create a sensitivity to general risk issues, thus providing a context for better interpretation of risk information

  16. Identification and evaluation of priorities in the business process of a risk or safety organization

    International Nuclear Information System (INIS)

    Teng, Kuei-Yung; Thekdi, Shital A.; Lambert, James H.

    2012-01-01

    Agencies are increasingly following principles and guidelines for the coordination of risk assessment, risk management, and risk communication in large-scale programs. In particular, there is a challenge to comply with the U.S. Office of Management and Budget (OMB) memorandum “Updated Principles for Risk Analysis” among other guidelines. This paper demonstrates a systemic approach to achieve compliance of a risk program with administrative and organizational principles and guidelines for risk analysis. The paper suggests three canonical questions as the mission of such a program: (i) what sources of risks are to be managed by the program, (ii) how should multiple risk assessment, risk management, and risk communication activities be administered and coordinated, and what should be the basis for resource allocation to these activities, and (iii) how will the performance of the program be monitored and evaluated. The paper demonstrates a re-prioritization of policy initiatives of the program based on emergent and future conditions. The approach is useful to agencies implementing risk or safety organizational guidelines such as those of the OMB, the US Government Accountability Office, the US Department of Homeland Security, the US Department of Defense, and others. This paper will be of interest to risk managers; agencies; and risk and safety analysts engaged in the conception, implementation, and evaluation of risk or safety programs. - Highlights: ► We develop a systemic approach for management of a risk or safety program. ► The approach includes business process models and policy prioritization. ► The results support organizations to implement risk and safety programs.

  17. Risk management study for the Hanford Site facilities: Risk reduction cost comparison for the retired Hanford Site facilities

    International Nuclear Information System (INIS)

    Coles, G.A.; Egge, R.G.; Senger, E.; Shultz, M.W.; Taylor, W.E.

    1994-02-01

    This document provides a cost-comparison evaluation for implementing certain risk-reduction measures and their effect on the overall risk of the 100 and 200 Area retired, surplus facilities. The evaluation is based on conditions that existed at the time the risk evaluation team performed facility investigations, and does not acknowledge risk-reduction measures that occurred soon after risk identification. This evaluation is one part of an overall risk management study for these facilities. The retired facilities investigated for this evaluation are located in the 100 and 200 Areas of the 1450-km 2 Hanford Site. The Hanford Site is a semiarid tract of land in southeastern Washington State. The nearest population center is Richland, Washington, (population 32,000) 30 km southeast of the 200 Area. This cost-comparison evaluation (1) determines relative costs for reducing risk to acceptable levels; (2) compares the cost of reducing risk using different risk-reduction options; and (3) compares the cost of reducing risks at different facilities. The result is an identification of the cost effective risk-reduction measures. Supporting information required to develop costs of the various risk-reduction options also is included

  18. SOCIAL STABILITY AND HIV RISK BEHAVIOR: EVALUATING THE ROLE OF ACCUMULATED VULNERABILITY

    Science.gov (United States)

    German, Danielle; Latkin, Carl A.

    2011-01-01

    This study evaluated a cumulative and syndromic relationship among commonly co-occurring vulnerabilites (homelessness, incarceration, low-income, residential transition) in association with HIV-related risk behaviors among 635 low-income women in Baltimore. Analysis included descriptive statistics, logistic regression, latent class analysis and latent class regression. Both methods of assessing multidimensional instability showed significant associations with risk indicators. Risk of multiple partners, sex exchange, and drug use decreased significantly with each additional domain. Higher stability class membership (77%) was associated with decreased likelihood of multiple partners, exchange partners, recent drug use, and recent STI. Multidimensional social vulnerabilities were cumulatively and synergistically linked to HIV risk behavior. Independent instability measures may miss important contextual determinants of risk. Social stability offers a useful framework to understand the synergy of social vulnerabilities that shape sexual risk behavior. Social policies and programs aiming to enhance housing and overall social stability are likely to be beneficial for HIV prevention. PMID:21259043

  19. Risk assessments for energy systems and role of preliminary degree-of-hazard evaluations

    International Nuclear Information System (INIS)

    Habegger, L.J.; Fingleton, D.J.

    1985-11-01

    The appropriate approach to risk or hazard assessment can vary considerably, depending on various factors, including the intended application of the results and the time other resources available to conduct the assessment. This paper illustrates three types of interrelated assessments. Although they can be mutually supportive, they have fundamentally different objectives, which require major differences in approach. The example of the overall risk assessment of alternative major energy technologies illustrates the compilation of a wide range of available risk data applicable to these systems. However, major uncertainties exist in the assessments, and public perception of their importance could play an important role in final system evaluations. A more narrowly defined risk assessment, often focusing on an individual component of a larger system, is the most commonly used approach in regulatory applications. The narrow scope allows in-depth analysis of risks and associated uncertainties, but it may also contribute to a loss of perspective on the magnitude of the assessed risk relative to that of the unassessed risks. In some applications, it is useful to conduct semiquantitative degree-of-hazard evaluations as a means of setting priorities for detailed risk assessment. The MAHAS procedure described in this paper provides a means of rapidly ranking relative hazards from various sources using easily accessible data. However, these rankings should not be used as definitive input for selecting technology alternatives or developing regulations. 25 refs., 6 tabs

  20. Mastery of risks and operational safety, risks and opportunities

    International Nuclear Information System (INIS)

    2004-01-01

    Creating socially useful richness is certainly the prime reason for companies to exist. Reaching this always moving target leads to seize opportunities and to take risks at the same time. For companies, risks and opportunities are two indissociable factors. Any decision making has to deal with an uncertain environment with random events of technological, economical, biological, human, environmental or natural origin. Because of the fear of uncertainty, risk acts as a brake to initiatives. In front of this problem, companies have to adopt a prevention policy based on a global and systemic approach, by identifying, evaluating, quantifying, sorting, mastering and managing unwanted events and by communicating about the way to treat them. In front of uncertainties, the operational safety, thanks to its methods and tools, supplies an incomparable contribution in the form of an help to any decision made with uncertainties. Operational safety contributes to the evaluation of costs and makes more realistic the economical estimations by taking into account the foreseeable and unforeseeable risks. The mastery of unwanted events, of their stakes and uncertainties, allows companies to carry out their projects in non-determined contexts and in a competitive environment. This colloquium concerns all socio-economical actors: industrialists, investors, decision makers, university and laboratory staffs, etc., who need a better evaluation of risks for a better mastery of their decisions in all sectors of activity. Seventeen papers of this conference, dealing with safety analysis and risk assessment at nuclear facilities and at other energy-related facilities, have been selected for Inis. (J.S.)

  1. Dutch Risk Assessment tools

    NARCIS (Netherlands)

    Venema, A.

    2015-01-01

    The ‘Risico- Inventarisatie- en Evaluatie-instrumenten’ is the name for the Dutch risk assessment (RA) tools. A RA tool can be used to perform a risk assessment including an evaluation of the identified risks. These tools were among the first online risk assessment tools developed in Europe. The

  2. Risk-adjusted Outcomes of Clinically Relevant Pancreatic Fistula Following Pancreatoduodenectomy: A Model for Performance Evaluation.

    Science.gov (United States)

    McMillan, Matthew T; Soi, Sameer; Asbun, Horacio J; Ball, Chad G; Bassi, Claudio; Beane, Joal D; Behrman, Stephen W; Berger, Adam C; Bloomston, Mark; Callery, Mark P; Christein, John D; Dixon, Elijah; Drebin, Jeffrey A; Castillo, Carlos Fernandez-Del; Fisher, William E; Fong, Zhi Ven; House, Michael G; Hughes, Steven J; Kent, Tara S; Kunstman, John W; Malleo, Giuseppe; Miller, Benjamin C; Salem, Ronald R; Soares, Kevin; Valero, Vicente; Wolfgang, Christopher L; Vollmer, Charles M

    2016-08-01

    To evaluate surgical performance in pancreatoduodenectomy using clinically relevant postoperative pancreatic fistula (CR-POPF) occurrence as a quality indicator. Accurate assessment of surgeon and institutional performance requires (1) standardized definitions for the outcome of interest and (2) a comprehensive risk-adjustment process to control for differences in patient risk. This multinational, retrospective study of 4301 pancreatoduodenectomies involved 55 surgeons at 15 institutions. Risk for CR-POPF was assessed using the previously validated Fistula Risk Score, and pancreatic fistulas were stratified by International Study Group criteria. CR-POPF variability was evaluated and hierarchical regression analysis assessed individual surgeon and institutional performance. There was considerable variability in both CR-POPF risk and occurrence. Factors increasing the risk for CR-POPF development included increasing Fistula Risk Score (odds ratio 1.49 per point, P ratio 3.30, P performance outliers were identified at the surgeon and institutional levels. Of the top 10 surgeons (≥15 cases) for nonrisk-adjusted performance, only 6 remained in this high-performing category following risk adjustment. This analysis of pancreatic fistulas following pancreatoduodenectomy demonstrates considerable variability in both the risk and occurrence of CR-POPF among surgeons and institutions. Disparities in patient risk between providers reinforce the need for comprehensive, risk-adjusted modeling when assessing performance based on procedure-specific complications. Furthermore, beyond inherent patient risk factors, surgical decision-making influences fistula outcomes.

  3. Mycophenolate fetal toxicity and risk evaluation and mitigation strategies.

    Science.gov (United States)

    Kim, M; Rostas, S; Gabardi, S

    2013-06-01

    The mycophenolic acid (MPA) preparations are one of the most commonly used immunosuppressants in the United States. However, these agents carry a black box warning regarding their use during pregnancy due to an association with increased risk of miscarriage and congenital defects. To ensure that the benefits of MPA outweigh the risks, the Food and Drug Administration (FDA) required all manufacturers of MPA products to propose risk evaluation and mitigation strategies (REMS). Four years after initially calling for proposals, the FDA approved a single shared REMS system in September 2012. The elements of the MPA REMS include a medication guide and elements to assure safe use (ETASU). The medication guide, which was previously FDA-approved in 2008, should continue to be distributed to patients, and the ETASU requires physicians to complete training and obtain patient signatures on the "Patient-Prescriber Acknowledgement Form." A single, national, voluntary pregnancy registry is available, and pregnant patients should be encouraged to participate. Although the impact of the MPA REMS on clinical practice is not clear, it is a step toward increasing the understanding of fetal risks with MPA products among patients and possibly practitioners. © Copyright 2013 The American Society of Transplantation and the American Society of Transplant Surgeons.

  4. Evaluation of severe accident risk in the Pickering a risk assessment

    International Nuclear Information System (INIS)

    Dinnie, K.S.; Raina, V.M.

    1997-01-01

    The nature of the design of commercial power plants is such that significant impacts on public health can only occur if a number of barriers fail. Rigorous design and licensing requirements ensure that the more likely accidents do not fail all these barriers and their contribution to risk is likely to be small. The task of estimating accident risk must, therefore, focus more towards those less likely but potentially more serious combinations of failures that are characterized by the following: a) a large release of fission products into the containment atmosphere, b) a breach in the containment envelope, and c) the existence of a driving force to expel the containment atmosphere to the outside environment. The likelihood of such conditions existing simultaneously during the course of an accident is expected to be small, such that experience and data regarding the behaviour of plant systems under such conditions is sparse or non-existent. The challenge of Probabilistic Safety Assessments (PSAs) is to examine the potential for severe accidents using approaches that are sufficiently detailed and realistic to provide valid information regarding plant risk and susceptibilities, while simple enough to keep the analysis manageable. This paper outlines the key features of the Pickering A Risk Assessment (PARA) (1) and the manner in which it addresses these issues, and provides some insights into the results and conclusions drawn from the study. (author)

  5. Risk management guide

    International Nuclear Information System (INIS)

    Briscoe, G.J.

    1977-06-01

    Risk management requires an assessment or a knowledge of risk. This, in turn, requires identification of hazards (sources of risk) and a determination of risk (evaluation of the hazard degree). The hazard identification and risk analysis techniques presented in this Guide are, in general, based on the MORT concept that accidents result from unwanted energy flow in the absence of adequate controls and/or barriers. This Guide presents an analytical tree designed to prevent oversight of specific energy sources in risk identification. Hazard identification by field personnel is also discussed. Quantitative risk analysis is discussed in the following section. A method for summary of the risks for each energy classification is given. This method uses a graphical log-normal projection so that low probability events, which are not adequately represented in the experience data, are included in the risk assessment. This permits a more acceptable risk assessment since catastrophes are not ignored, even though the actual risk is only approximated. In addition, a few examples of risk analysis of specific hazards are given. Rudimentary probability and fault tree theory are used in these examples. Total risk assessment and resource allocation and safety performance trend analysis are discussed

  6. Development and evaluation of an automated fall risk assessment system.

    Science.gov (United States)

    Lee, Ju Young; Jin, Yinji; Piao, Jinshi; Lee, Sun-Mi

    2016-04-01

    Fall risk assessment is the first step toward prevention, and a risk assessment tool with high validity should be used. This study aimed to develop and validate an automated fall risk assessment system (Auto-FallRAS) to assess fall risks based on electronic medical records (EMRs) without additional data collected or entered by nurses. This study was conducted in a 1335-bed university hospital in Seoul, South Korea. The Auto-FallRAS was developed using 4211 fall-related clinical data extracted from EMRs. Participants included fall patients and non-fall patients (868 and 3472 for the development study; 752 and 3008 for the validation study; and 58 and 232 for validation after clinical application, respectively). The system was evaluated for predictive validity and concurrent validity. The final 10 predictors were included in the logistic regression model for the risk-scoring algorithm. The results of the Auto-FallRAS were shown as high/moderate/low risk on the EMR screen. The predictive validity analyzed after clinical application of the Auto-FallRAS was as follows: sensitivity = 0.95, NPV = 0.97 and Youden index = 0.44. The validity of the Morse Fall Scale assessed by nurses was as follows: sensitivity = 0.68, NPV = 0.88 and Youden index = 0.28. This study found that the Auto-FallRAS results were better than were the nurses' predictions. The advantage of the Auto-FallRAS is that it automatically analyzes information and shows patients' fall risk assessment results without requiring additional time from nurses. © The Author 2016. Published by Oxford University Press in association with the International Society for Quality in Health Care; all rights reserved.

  7. Man, technology and risk

    Energy Technology Data Exchange (ETDEWEB)

    Renn, O

    1981-06-01

    Using the instruments of empirical social sciences, a cross-section study was conducted comprising experiments on qualitative risk characteristics, in-depth interviews on mechanisms of risk perception and representative surveys of the public on technical risk sources, in particular with regard to nuclear energy. The results of these studies show that person-related expectations in respect of risk consequences, the possibility of personal influencing control, the severeness of risk consequences and one's own risk propensity play a significant role in the evaluation of risks. (Translated from German, original report Juel-Spez--67).

  8. Risk evaluation of cosmic-ray exposure in long-term manned space mission

    International Nuclear Information System (INIS)

    Fujitaka, Kazunobu; Majima, Hideyuki; Ando, Koichi; Yasuda, Hiroshi; Suzuki, Masao

    1999-03-01

    Long-term manned space missions are planned to be implemented within the first two decades of the 21st century. The International Space Station (ISS) will be ready to run, and a plan to visit Mars is also under way. Humans will live in space for long periods of time and we are planning to do experiments in space to examine various aspects of space science. The main risk in long-term manned space missions is large exposure to space radiation. Human safety must be ensured in space where exposure to cosmic rays is almost 1 mSv a day. As such missions will inevitably result in significant exposure for astronauts, there is increasing need to protect them adequately based on both physical and biological knowledge. A good method to evaluate realistic risk associated with space missions will be in urgent demand. At the National Institute of Radiological Sciences (NIRS), Chiba, Japan, a research institutes of the Science Technology Agency of Japan, high energy cosmic radiation can be simulated only with heavy ion irradiation accelerated by the particle accelerator, Heavy Ion Medical Accelerator (HIMAC). Research to evaluate risk of space radiation, including physical measurement techniques, protective effects, biological effects and risk adjustment, aging, neuronal cell damage and cancer risk are undergoing. We organized a workshop of the latest topics and experimental results of physics and biology related to space radiation supported by Japan Science and Technology Corporation (JST). This workshop was held as a satellite meeting associated with the 32nd Committee on Space Research (COSPAR) Scientific Assembly (Nagoya, July 12-19th, 1998). This volume is an extended proceedings of the workshop. The proceedings contain six main subjects covering the latest information on Risk Evaluation of Cosmic-Ray Exposure in Long-Term Manned Space Mission'. 1. Risk Estimation of Heavy Ion Exposure in Space. 2. Low Dose-Rate Effects and Microbeam-Related Heavy Ions. 3. Chromosome and

  9. 77 FR 26292 - Risk Evaluation and Mitigation Strategy Assessments: Social Science Methodologies to Assess Goals...

    Science.gov (United States)

    2012-05-03

    ...] Risk Evaluation and Mitigation Strategy Assessments: Social Science Methodologies to Assess Goals... announcing a public workshop entitled ``Risk Evaluation and Mitigation Strategy Assessments: Social Science... constructive dialogue and information-sharing among regulators, researchers, the pharmaceutical industry...

  10. [Pollution Evaluation and Risk Assessment of Heavy Metals from Atmospheric Deposition in the Parks of Nanjing].

    Science.gov (United States)

    Wang, Cheng; Qian, Xin; Li, Hui-ming; Sun, Yi-xuan; Wang, Jin-hua

    2016-05-15

    Contents of heavy metals involving As, Cd, Cr, Cu, Ni, Pb and Zn from atmospheric deposition in 10 parks of Nanjing were analyzed. The pollution level, ecological risk and health risk were evaluated using Geoaccumulation Index, Potential Ecological Risk Index and the US EPA Health Risk Assessment Model, respectively. The results showed that the pollution levels of heavy metals in Swallow Rock Park, Swallow Rock Park and Mochou Lake Park were higher than the others. Compared to other cities such as Changchun, Wuhan and Beijing, the contents of heavy metals in atmospheric deposition of parks in Nanjing were higher. The evaluation results of Geoaccumulation Index showed that Pb was at moderate pollution level, Zn and Cu were between moderate and serious levels, while Cd was between serious and extreme levels. The ecological risk level of Cd was high. The assessment results of Health Risk Assessment Model indicated that there was no non-carcinogenic risk for all the seven heavy metals. For carcinogenic risk, the risks of Cd, Cr and Ni were all negligible (Risk < 1 x 10⁻⁶), whereas As had carcinogenic risk possibility but was considered to be acceptable (10⁻⁶ < Risk < 10⁻⁴).

  11. Food and Drug Administration Evaluation and Cigarette Smoking Risk Perceptions

    Science.gov (United States)

    Kaufman, Annette R.; Waters, Erika A.; Parascandola, Mark; Augustson, Erik M.; Bansal-Travers, Maansi; Hyland, Andrew; Cummings, K. Michael

    2011-01-01

    Objectives: To examine the relationship between a belief about Food and Drug Administration (FDA) safety evaluation of cigarettes and smoking risk perceptions. Methods: A nationally representative, random-digit-dialed telephone survey of 1046 adult current cigarette smokers. Results: Smokers reporting that the FDA does not evaluate cigarettes for…

  12. Engineering risks

    International Nuclear Information System (INIS)

    Hauptmanns, U.; Werner, W.

    1991-01-01

    The book describes the methods of risk analysis and explains the procedures and results of a number of studies including the German Risk Study, Phase B and NUREG-1150. After defining basic concepts the methods of risk analysis are treated. In the field of nuclear energy studies for light water, fast breeder and high temperature reactors and for the nuclear fuel cycle are discussed; their relevant results are presented. Additionally, precursors to severe accidents are dealt with. Risk studies for process plants are described; their objectives and methods of analysis are examined. Furthermore, their approaches are compared with that of the German Risk Study, Phase A. Risk comparisons for nuclear, conventional and renewable energy sources are critically examined. Technical and legal aspects of the safety evaluation for nuclear power plants in the FRG and the potential of the combined use of the deterministic and probabilistic approaches are discussed. The book concludes with an overview of probabilistic safety goals in different countries. (orig.) With 52 figs

  13. New Metrics for Evaluating Technical Benefits and Risks of DGs Increasing Penetration

    DEFF Research Database (Denmark)

    Akbari, Mohammad Amin; Aghaei, Jamshid; Barani, Mostafa

    2017-01-01

    and risks should be qualified and quantified. This paper introduces several probabilistic indices to evaluate the potential operational effects of increasing penetration of renewable DG units such as wind power and photovoltaic on rural distribution network with the aid of evaluating technical benefits...... and risks trade-offs. A probabilistic generation-load model is suggested to calculate these indices which combine a large number of possible operating conditions of renewable DG units with their probabilities. Temporal and annual indices of voltage profile and line flow related attributes such as Interest...... Voltage Rise (IVR), Risky Voltage Rise (RVR), Risky Voltage Down (RVD), Line Loss Reduction (LLR), Line Loss Increment (LLI) and Line overload flow (LOF) are introduced using probability and expected values of their occurrence. Also, to measure the overall interests and risks of installing DG, composite...

  14. Managing the total cost of risk exposures through risk mapping techniques

    International Nuclear Information System (INIS)

    Unione, A.J.; Rode, D.M.

    1998-01-01

    In a competitive power market, power producers are exposed to an increasingly broad spectrum of financial risks. The cumulative impact of these financial risks is known collectively as the Total of Cost of Risk. The concept of Total of Cost of Risk presents the business reality of a company's exposure to potentially devastating financial consequences in an integrated and useful way. In this way, a strategy of managing Total Cost of Risk in the most cost effective way can become a means of ensuring long term business health and security. This paper will examine the use of risk mapping as a tool for visually understanding Total Cost of Risk, thus creating an enhanced situational awareness and an integrated basis for risk management decision. The evaluation process, available through the use of risk maps allows the power producers to pro-actively implement prudent business decisions concerning the design, operation and maintenance of power plants. Risk mapping is thus a means for harmonizing operational objectives, such as improved plant reliability, with corporate strategies and goals in terms of an effective risk management program

  15. Evaluation of ergonomic risk factors in manual patient handling ...

    African Journals Online (AJOL)

    WMSDs among nurses in West Bengal, India, evaluates the postural stresses and analyses manual patient handling risks. Responses were collected from 220 nurses by validated questionnaires. The activity and posture analyses were done through photography and by Rapid Entire Body Assessment (REBA). Results ...

  16. Evaluating Mediterranean Soil Contamination Risks in Selected Hydrological Scenarios.

    NARCIS (Netherlands)

    Rosa, de la D.; Crompvoets, J.

    1997-01-01

    This paper reports an attempt of predicting the contamination risk of soils and water as they respond to hydrological changes in the agricultural lands of Sevilla province, Spain. Based on land evaluation methodologies, a semi-empirical model (named Pantanal, as module of the integrated package

  17. [How to evaluate psychological risks: an ethics of aesthetic demand in orthodontics].

    Science.gov (United States)

    Benkimoun, Franck

    2015-12-01

    Evaluating risks is part of the day-to-day practice of all orthodontists. Most of the time we forget that healing a patient also requires an evaluation of what is called the psychological risk. Indeed, focusing on harmonisation matters, we tend to omit that patient's requests, especially aesthetic requests, may conceal psychological problems. Such a risk is even higher when it comes to orthodontic-surgical protocols, as the physical changes are more radical. We will discuss the specificities of aesthetical demand, its links with the social discourse and the way self-esteem and reflection in the mirror are closely intermingled. Should we forget to take into account the psychological dimension of any patient, this could be a breach of professional ethics. We will furthermore consider the means we have to recognize patients with a high psychological risk. It is not in our hands to help these patients psychologically. It is in the hands of a mental health specialist, whose adress and phone number we should know in order to refer our patients to him/her. © EDP Sciences, SFODF, 2015.

  18. Technical specifications review of nuclear power plants: a risk-informed evaluation

    International Nuclear Information System (INIS)

    Saldanha, Pedro Luiz da Cruz; Sousa, Anna Leticia; Frutuoso e Melo, Paulo Fernando Ferreira; Duarte, Juliana Pacheco

    2012-01-01

    The use of risk information by a regulatory body as part of an integrated decision making process addresses the way in which risk information is being used as part of an integrated process in making decisions about safety issues at nuclear plants – commonly referred to as risk-informed decision making. The risk-informed approach aims to integrate in a systematic manner quantitative and qualitative, deterministic and probabilistic safety considerations to obtain a balanced decision. Probabilistic Safety Assessment (PSA) is a methodology that can be applied to provide a structured analysis process to evaluate the frequency and consequences of accidents scenarios in nuclear power plants. Technical Specifications (TS) are specifications regarding the characteristics of nuclear power plants (variables, systems or components) of overriding importance to nuclear safety and radiation protection, which is an integral part of plant operation authorization. Limiting Conditions of Operation (LCO) are the minimum levels of performance or capacity or operating system components required for the safe operation of nuclear plants, as defined in technical specifications. The Maintenance Rule (MR) is a requirement established by the U. S. Nuclear Regulatory Commission (NRC) to check the effectiveness of maintenance carried out in nuclear plants, and plant configuration control. The control of plant configuration is necessary to verify the impact of the maintenance of a safety device out of service on plant safety. The Electric Power Research Institute (EPRI) has assessed the role of probabilistic safety analysis in the regulation of nuclear power plants with the following objectives: a) to provide utilities with an approach for developing and implementing nuclear power station risk-managed technical specification programs; and b) to complement and supplement existing successful configuration risk management applications such as MR. This paper focuses on the evaluation of EPRI

  19. An evaluation of a risk-based environmental regulation in Brazil: Limitations to risk management of hazardous installations

    International Nuclear Information System (INIS)

    Naime, Andre

    2017-01-01

    The environmental regulation of hazardous projects with risk-based decision-making processes can lead to a deficient management of human exposure to technological hazards. Such an approach for regulation is criticized for simplifying the complexity of decisions involving the economic, social, and environmental aspects of the installation and operation of hazardous facilities in urban areas. Results of a Brazilian case study indicate that oil and gas transmission pipelines may represent a threat to diverse communities if the relationship between such linear projects and human populations is overlooked by regulatory bodies. Results also corroborate known challenges to the implementation of EIA processes and outline limitations to an effective environmental and risk management. Two preliminary topics are discussed to strengthen similar regulatory practices. Firstly, an effective integration between social impact assessment and risk assessment in EIA processes to have a more comprehensive understanding of the social fabric. Secondly, the advancement of traditional management practices for hazardous installations to pursue a strong transition from assessment and evaluation to management and control and to promote an effective interaction between land-use planning and environmental regulation.

  20. An evaluation of a risk-based environmental regulation in Brazil: Limitations to risk management of hazardous installations

    Energy Technology Data Exchange (ETDEWEB)

    Naime, Andre, E-mail: andre.naime.ibama@gmail.com

    2017-03-15

    The environmental regulation of hazardous projects with risk-based decision-making processes can lead to a deficient management of human exposure to technological hazards. Such an approach for regulation is criticized for simplifying the complexity of decisions involving the economic, social, and environmental aspects of the installation and operation of hazardous facilities in urban areas. Results of a Brazilian case study indicate that oil and gas transmission pipelines may represent a threat to diverse communities if the relationship between such linear projects and human populations is overlooked by regulatory bodies. Results also corroborate known challenges to the implementation of EIA processes and outline limitations to an effective environmental and risk management. Two preliminary topics are discussed to strengthen similar regulatory practices. Firstly, an effective integration between social impact assessment and risk assessment in EIA processes to have a more comprehensive understanding of the social fabric. Secondly, the advancement of traditional management practices for hazardous installations to pursue a strong transition from assessment and evaluation to management and control and to promote an effective interaction between land-use planning and environmental regulation.

  1. Survey and evaluation of aging risk assessment methods and applications

    International Nuclear Information System (INIS)

    Sanzo, D.; Kvam, P.; Apostolakis, G.; Wu, J.; Milici, T.; Ghoniem, N.; Guarro, S.

    1994-11-01

    The US Nuclear Regulatory Commission initiated the nuclear power plant aging research program about 6 years ago to gather information about nuclear power plant aging. Since then, this program has collected a significant amount of information, largely qualitative, on plant aging and its potential effects on plant safety. However, this body of knowledge has not yet been integrated into formalisms that can be used effectively and systematically to assess plant risk resulting from aging, although models for assessing the effect of increasing failure rates on core damage frequency have been proposed. This report surveys the work on the aging of systems, structures, and components (SSCs) of nuclear power plants, as well as associated data bases. We take a critical look at the need to revise probabilistic risk assessments (PRAs) so that they will include the contribution to risk from plant aging, the adequacy of existing methods for evaluating this contribution, and the adequacy of the data that have been used in these evaluation methods. We identify a preliminary framework for integrating the aging of SSCs into the PRA and include the identification of necessary data for such an integration

  2. Development of risk matrices for evaluating climatic change responses of forested habitats

    Science.gov (United States)

    Louis R. Iverson; Stephen N. Matthews; Anantha M. Prasad; Matthew P. Peters; Gary. Yohe

    2012-01-01

    We present an approach to assess and compare risk from climate change among multiple species through a risk matrix, in which managers can quickly prioritize for species that need to have strategies developed, evaluated further, or watched. We base the matrix upon earlier work towards the National Climate Assessment for potential damage to infrastructures from climate...

  3. A critical evaluation of risk-return characteristics of environmentally focused stock’s companies

    Directory of Open Access Journals (Sweden)

    Stanislav Škapa

    2013-01-01

    Full Text Available The objective of the paper is to critically evaluate and determine risk-return profile environmentally focused stock’s companies which are covered by STOXX Global ESG Environmental Leaders Index and whether this index should be taken in as an independent asset class of investments portfolio for its risk-return improvement. This paper gives an empirical view on the ex-post asset classes characteristics focused mainly on risk side of investment.

  4. Evaluating Process Effectiveness to Reduce Risk

    Science.gov (United States)

    Shepherd, Christena C.

    2017-01-01

    security; loss of confidence in government; failure of publicly funded projects; damage to the environment; ethics violations, and the list goes on; with local, national and even international consequences. The Plan-Do-Check-Act process, also known as the "process approach" can be used at any time to establish and standardize a process, and it can also be used to check periodically for "process creep" (i.e., informal, unauthorized changes that have occurred over time), any necessary updates and improvements. While ISO 9001 compliance is not mandated for all government agencies, if interpreted correctly, it can be useful in establishing a framework and implementing effective management systems and processes.4 Another method that can be used to evaluate effectiveness is the scorecard definitions in Mallory's Process Management Standard5 as a basis for evaluating work on the process level on effective, and continuously improved and improving processes. With processes on the lower end of the scale, agencies are vulnerable to a great many risks, with employees and managers making up many of the rules as they go, leading to the above listed negative results. Without clear guidance for nominal operations, off-nominal situations can, and do, increase the likelihood of chaos. In an increasingly technical environment, with inter-agency communication and collaboration becoming the norm, agencies need to come to grips with the fact that processes can become rapidly outdated, and that the technical community should take on an increased role in the maturation of the agency's processes. Industry has long known that effective processes are also efficient, and process improvement methods such as Kaizen, Lean, Six Sigma, 5S, and mistake proofing lead to increased productivity, improved quality, and decreased cost. Again, government agencies have different concerns, but inefficiencies and mistakes can have dire and wide reaching consequences for the public that they serve. While no one goes

  5. Credit Risk Evaluation System For Nigerian Banks Using Artificial Ne

    African Journals Online (AJOL)

    MANKABS

    CREDIT RISK EVALUATION SYSTEM: AN ARTIFICIAL NEURAL NETWORK APPROACH of their own experiential .... limitations concern the high computational ... Number of existing credits at this bank. 7. Personal status and sex. 14. Job. 17.

  6. Evaluation of the risks linked with natural refrigerating fluids; Evaluation des risques lies aux fluides frigorigenes naturels

    Energy Technology Data Exchange (ETDEWEB)

    Guilpart, J. [Centre National Machiniste Agricole du Genie Rural des Eaux et des Forets, (Cemagref), 35 - Rennes (France). Div. Genie des Procedes Frigorifiques

    1999-07-01

    Because of their environmental impact, halogenated refrigerants are more and more replaced by `natural` refrigerants in vapor compression cycle refrigerating machineries. However, technological risks exist with these substitution fluids due to their flammability, explosibility or toxicity. Major risks can be encountered at the industrial scale and thanks to experience feedback and to several studies, a rigorous approach was settled and included in the legislative texts relative to classified installations and environment protection. Risks also exist at the scale of refrigerating installations with the use of hydrocarbon and ammonia refrigerants. This paper presents an evaluation of risks both at the industrial and at the installation scale: 1 - definition and approach of industrial risks: scenarios of major industrial accidents (boiling liquid expanding vapor explosion (BLEVE), unconfined vapor cloud explosion (UVCE), toxic gases emission); evaluation of accident effects (thermal, mechanical, noxious); 2 - calculation methods applicable to industrial installations: thermal effects (radiation intensity, exposure duration, mass of flammable product involved in the phenomenon), mechanical effects (TNT equivalent method, rupture of pressurized reservoirs), noxious effects (leaks, atmospheric dispersion); 3 - application to refrigerating installations: case of hydrocarbons (dimensioning scenarios and simplified formulae, admissible scenarios), case of ammonia. (J.S.) 20 refs.

  7. A Bayesian approach to the evaluation of risk-based microbiological criteria for Campylobacter in broiler meat

    DEFF Research Database (Denmark)

    Ranta, Jukka; Lindqvist, Roland; Hansson, Ingrid

    2015-01-01

    Shifting from traditional hazard-based food safety management toward risk-based management requires statistical methods for evaluating intermediate targets in food production, such as microbiological criteria (MC), in terms of their effects on human risk of illness. A fully risk-based evaluation...... of MC involves several uncertainties that are related to both the underlying Quantitative Microbiological Risk Assessment (QMRA) model and the production-specific sample data on the prevalence and concentrations of microbes in production batches. We used Bayesian modeling for statistical inference...

  8. The Risk-Stratified Osteoporosis Strategy Evaluation study (ROSE)

    DEFF Research Database (Denmark)

    Rubin, Katrine Hass; Holmberg, Teresa; Rothmann, Mette Juel

    2015-01-01

    The risk-stratified osteoporosis strategy evaluation study (ROSE) is a randomized prospective population-based study investigating the effectiveness of a two-step screening program for osteoporosis in women. This paper reports the study design and baseline characteristics of the study population....... 35,000 women aged 65-80 years were selected at random from the population in the Region of Southern Denmark and-before inclusion-randomized to either a screening group or a control group. As first step, a self-administered questionnaire regarding risk factors for osteoporosis based on FRAX......(®) was issued to both groups. As second step, subjects in the screening group with a 10-year probability of major osteoporotic fractures ≥15 % were offered a DXA scan. Patients diagnosed with osteoporosis from the DXA scan were advised to see their GP and discuss pharmaceutical treatment according to Danish...

  9. U.S. Civil Air Show Crashes, 1993 to 2013: Burden, Fatal Risk Factors, and Evaluation of a Risk Index for Aviation Crashes.

    Science.gov (United States)

    Ballard, Sarah-Blythe; Osorio, Victor B

    2015-01-01

    This study provides new public health data about U.S. civil air shows. Risk factors for fatalities in civil air show crashes were analyzed. The value of the FIA score in predicting fatal outcomes was evaluated. With the use of the FAA's General Aviation and Air Taxi Survey and the National Transportation Safety Board's data, the incidence of civil air show crashes from 1993 to 2013 was calculated. Fatality risk factors for crashes were analyzed by means of regression methods. The FIA index was validated to predict fatal outcomes by using the factors of fire, instrument conditions, and away-from-airport location, and was evaluated through receiver operating characteristic (ROC) curves. The civil air show crash rate was 31 crashes per 1,000 civil air events. Of the 174 civil air show crashes that occurred during the study period, 91 (52%) involved at least one fatality; on average, 1.1 people died per fatal crash. Fatalities were associated with four major risk factors: fire [adjusted odds ratio (AOR) = 7.1, 95% confidence interval (CI) = 2.4 to 20.6, P Civil air show crashes were marked by a high risk of fatal outcomes to pilots in aerobatic performances but rare mass casualties. The FIA score was not a valid measurement of fatal risk in civil air show crashes.

  10. Methodology evaluation of innovative projects under risk and uncertainty

    Directory of Open Access Journals (Sweden)

    2012-09-01

    Full Text Available This article deals with problems connected with the assessment of innovative projects in the context of risk and uncertainty, topical issues of evaluation of innovative projects at the present stage of development of the Russian economy. By the example of the solution of the "crossing the river" is considering the possibility of using hierarchical models to address it. In what follows, and compares the priorities of different groups of factors are given by calculating the overall costs and benefits. The paper provides a rationale for combined use of four aspects: the beneficial aspects of the decision (the benefits and opportunities and negative (costs and risks that may lead to the decision in question.

  11. [Application of risk grading and classification for occupational hazards in risk management for a shipbuilding project].

    Science.gov (United States)

    Zeng, Wenfeng; Tan, Qiang; Wu, Shihua; Deng, Yingcong; Liu, Lifen; Wang, Zhi; Liu, Yimin

    2015-12-01

    To investigate the application of risk grading and classification for occupational hazards in risk management for a shipbuilding project. The risk management for this shipbuilding project was performed by a comprehensive application of MES evaluation, quality assessment of occupational health management, and risk grading and classification for occupational hazards, through the methods of occupational health survey, occupational health testing, and occupational health examinations. The results of MES evaluation showed that the risk of occupational hazards in this project was grade 3, which was considered as significant risk; Q value calculated by quality assessment of occupational health management was 0.52, which was considered to be unqualified; the comprehensive evaluation with these two methods showed that the integrated risk rating for this shipbuilding project was class D, and follow- up and rectification were needed with a focus on the improvement in health management. The application of MES evaluation and quality assessment of occupational health management in risk management for occupational hazards can achieve objective and reasonable conclusions and has good applicability.

  12. Cost-oriented evaluation of ecosystem services under consideration of income risks and risk attitudes of farmers.

    Science.gov (United States)

    Dörschner, T; Musshoff, O

    2013-09-30

    Agri-environmental measures are often not as accepted among farmers as is expected. The present study investigates whether changes in income risks and the individual risk attitudes of farmers may constitute an explanatory approach for the low acceptance of the measures. For this purpose, a normative model is developed that calculates the premia claimed by the farmers for adopting environmental measures under the consideration of income risks and different risk attitudes. We apply this model to environmental measures aiming at an increase of the faunistic diversity of species on grassland and showing that changes in income risks and the decision makers' risk attitudes can significantly influence farmers' minimum compensation claims. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. Impact of risk factors on cardiovascular risk: a perspective on risk estimation in a Swiss population.

    Science.gov (United States)

    Chrubasik, Sigrun A; Chrubasik, Cosima A; Piper, Jörg; Schulte-Moenting, Juergen; Erne, Paul

    2015-01-01

    In models and scores for estimating cardiovascular risk (CVR), the relative weightings given to blood pressure measurements (BPMs), and biometric and laboratory variables are such that even large differences in blood pressure lead to rather low differences in the resulting total risk when compared with other concurrent risk factors. We evaluated this phenomenon based on the PROCAM score, using BPMs made by volunteer subjects at home (HBPMs) and automated ambulatory BPMs (ABPMs) carried out in the same subjects. A total of 153 volunteers provided the data needed to estimate their CVR by means of the PROCAM formula. Differences (deltaCVR) between the risk estimated by entering the ABPM and that estimated with the HBPM were compared with the differences (deltaBPM) between the ABPM and the corresponding HBPM. In addition to the median values (= second quartile), the first and third quartiles of blood pressure profiles were also considered. PROCAM risk values were converted to European Society of Cardiology (ESC) risk values and all participants were assigned to the risk groups low, medium and high. Based on the PROCAM score, 132 participants had a low risk for suffering myocardial infarction, 16 a medium risk and 5 a high risk. The calculated ESC scores classified 125 participants into the low-risk group, 26 into the medium- and 2 into the high-risk group for death from a cardiovascular event. Mean ABPM tended to be higher than mean HBPM. Use of mean systolic ABPM or HBPM in the PROCAM formula had no major impact on the risk level. Our observations are in agreement with the rather low weighting of blood pressure as risk determinant in the PROCAM score. BPMs assessed with different methods had relatively little impact on estimation of cardiovascular risk in the given context of other important determinants. The risk calculations in our unselected population reflect the given classification of Switzerland as a so-called cardiovascular "low risk country".

  14. Beyond risk: a psychometric and cultural analysis of risk percepion in Korea

    International Nuclear Information System (INIS)

    Choi, Byung-Sun; Chung, Ik Jae

    2002-01-01

    A survey of technological risk perception in Korea was administered in 2001 with a special emphasis on nuclear risks. This paper summarizes the characteristics of risk perception through the analytic lens of psychometric paradigm. A group of experts identified 8 dimensions of risk; voluntariness, severity, effect manifestation, exposure pattern, controllability, familiarity, benefit and necessity. The survey with sample size of 1870 evaluates the perceived level of 25 technological risks including transportation, chemicals, environmental, industrial, as well as nuclear areas. Research findings confirm that the risk characteristics or dimensions are significant predictors of risk perception. Nuclear risks are perceived as involuntary, catastrophic, delayed, occasional, controllable, beneficiary, unfamiliar, and necessary. The paper underlines the need and the importance of nuclear power generation as an environmentally-friendly energy resource in Korea. Effective risk communication can improve the awareness and the understanding of nuclear risks as well as other technological risk, and ultimately foster the public acceptance of nuclear facilities

  15. Baseline risk and marginal willingness to pay for health risk reduction.

    Science.gov (United States)

    Gerking, Shelby; Adamowicz, Wiktor; Dickie, Mark; Veronesi, Marcella

    2017-01-01

    Empirical results presented in this paper suggest that parents' marginal willingness to pay (MWTP) for a reduction in morbidity risk from heart disease is inversely related to baseline risk (i.e., the amount of risk initially faced) both for themselves and for their children. For instance, a 40% reduction from the mean of baseline risk results in an increase in MWTP by 70% or more. Thus, estimates of monetary benefits of public programs to reduce heart disease risk would be understated if the standard practice is followed of evaluating MWTP at initial risk levels and then multiplying this value by the number of cases avoided. Estimates are supported by: (1) unique quantitative information on perceptions of the risk of getting heart disease that allow baseline risk to be defined at an individual level and (2) improved econometric procedures to control for well-known difficulties associated with stated preference data.

  16. Packaging and transportation risk management and evaluation plan

    International Nuclear Information System (INIS)

    Rhyne, W.R.

    1993-09-01

    Shipments of radioactive materials and hazardous chemicals at the Los Alamos National Laboratory (LANL) are governed by a variety of Federal and state regulations, industrial standards, and LANL processes and procedures. Good judgement is exercised in situations that are not covered by regulations. As a result, the safety record for transporting hazardous materials at LANL has been excellent. However, future decisions should be made such that the decision-making process produces a defensible record of the safety of onsite shipments. This report proposes the development of a risk management tool to meet this need. First, the application of quantitative risk analysis methodology to transportation is presented to provide a framework of understanding. Risk analysis definitions, the basic quantitative risk analysis procedure, quantitative methodologies, transportation data bases, and risk presentation techniques are described. Quantitative risk analysis is frequently complex; but simplified approaches can be used as a management tool to make good decisions. Second, a plan to apply the use of risk management principles to the selection of routes, special administrative controls, and containers for hazardous material transportation at LANL is provided. A risk management tool is proposed that can be used by MAT-2 without substantial support from specialized safety and risk analysis personnel, e.g., HS-3. A workbook approach is proposed that can be automated at a later date. The safety of some types of onsite shipments at LANL is not well documented. Documenting that shipments are safe, i.e., present acceptable risks, will likely require elaborate analyses that should be thoroughly reviewed by safety and risk professionals. These detailed analyses are used as benchmarks and as examples for the use of the proposed tool by MAT-2. Once the benchmarks are established, the workbook can be used by MAT-2 to quantify that safety goals are met by similar shipments

  17. The gamma knife: Dose and risk evaluation

    International Nuclear Information System (INIS)

    Jones, E.D.; Alesso, H.P.; Banks, W.W.; Rathbun, P.A.

    1992-01-01

    This paper outlines a risk analysis approach designed to identify and assess most likely failure modes and high-risk, human initiated actions for nuclear medical devices. This approach is being developed under the auspices of the US Nuclear Regulatory Commission, Office of Nuclear Material Safety and Safeguards. The methodology is initiated intended to assess risk associated with the use of the Leksell Gamma Unit (LGU) or gamma knife, a gamma stereotactic radiosurgical device

  18. Risk evaluation and mitigation strategies: a focus on the mammalian target of rapamycin inhibitors.

    Science.gov (United States)

    Gabardi, Steven

    2013-03-01

    To review the history of risk evaluation and mitigation strategies (REMS) with the mammalian target of rapamycin (mToR) inhibitors, evaluate their required REMS elements, and delineate the reasons for them being released from their REMS requirements. Articles were identified through a literature search of MEDLINE and EMBASE (January 2007-July 2012) using the search terms: risk evaluation and mitigation strategies, REMS, everolimus, sirolimus and organ transplant (individual organs also were searched). Information from the Federal Register, the Food and Drug Administration, and the manufacturers of the mToR inhibitors was also evaluated. REMS are strategies implemented to manage known or potential risks associated with medications and to ensure ongoing pharmacovigilance throughout the life of a pharmaceutical product. The mToR inhibitors have been associated with several potential risks, including proteinuria, graft thrombosis, and wound-healing complications. The Food and Drug Administration approved REMS programs for both sirolimus and everolimus. The manufacturers of both medications complied with the components of their approved REMS, but after less than 2 years, both medications have been relieved of their REMS obligations. The only element of the sirolimus REMS was a medication guide, whereas the everolimus REMS consisted of a medication guide and a communication plan. The sirolimus REMS was implemented more than 10 years after its initial approval by the Food and Drug Administration, but was released from its REMS requirement within 7 months of its implementation. The everolimus REMS was instituted upon initial approval and was removed approximately 2 years later. Both medications' REMS were always intended to educate health care providers and patients about the potential risks associated with this transplant immunosuppressant. Transplant practitioners should be familiar with the mToR inhibitors' associated risks and properly educate patients regarding the

  19. Measuring Risk Perception in Later Life: The Perceived Risk Scale.

    Science.gov (United States)

    Lifshitz, Rinat; Nimrod, Galit; Bachner, Yaacov G

    2016-11-01

    Risk perception is a subjective assessment of the actual or potential threat to one's life or, more broadly, to one's psychological well-being. Given the various risks associated with later life, a valid and reliable integrative screening tool for assessing risk perception among the elderly is warranted. The study examined the psychometric properties and factor structure of a new integrative risk perception instrument, the Perceived Risk Scale. This eight-item measure refers to various risks simultaneously, including terror, health issues, traffic accidents, violence, and financial loss, and was developed specifically for older adults. An online survey was conducted with 306 participants aged 50 years and older. The scale was examined using exploratory factor analysis and concurrent validity testing. Factor analysis revealed a two-factor structure: later-life risks and terror risks A high percentage of explained variance, as well as internal consistency, was found for the entire scale and for both factors. Concurrent validity was supported by significant positive associations with participants' depression and negative correlations with their life satisfaction. These findings suggest that the Perceived Risk Scale is internally reliable, valid, and appropriate for evaluating risk perception in later life. The scale's potential applications are discussed. © The Author(s) 2016.

  20. Geographic exposure risk of variant Creutzfeldt-Jakob disease in US blood donors: a risk-ranking model to evaluate alternative donor-deferral policies.

    Science.gov (United States)

    Yang, Hong; Huang, Yin; Gregori, Luisa; Asher, David M; Bui, Travis; Forshee, Richard A; Anderson, Steven A

    2017-04-01

    Variant Creutzfeldt-Jakob disease (vCJD) has been transmitted by blood transfusion (TTvCJD). The US Food and Drug Administration (FDA) recommends deferring blood donors who resided in or traveled to 30 European countries where they may have been exposed to bovine spongiform encephalopathy (BSE) through beef consumption. Those recommendations warrant re-evaluation, because new cases of BSE and vCJD have markedly abated. The FDA developed a risk-ranking model to calculate the geographic vCJD risk using country-specific case rates and person-years of exposure of US blood donors. We used the reported country vCJD case rates, when available, or imputed vCJD case rates from reported BSE and UK beef exports during the risk period. We estimated the risk reduction and donor loss should the deferral be restricted to a few high-risk countries. We also estimated additional risk reduction by leukocyte reduction (LR) of red blood cells (RBCs). The United Kingdom, Ireland, and France had the greatest vCJD risk, contributing approximately 95% of the total risk. The model estimated that deferring US donors who spent extended periods of time in these three countries, combined with currently voluntary LR (95% of RBC units), would reduce the vCJD risk by 89.3%, a reduction similar to that achieved under the current policy (89.8%). Limiting deferrals to exposure in these three countries would potentially allow donations from an additional 100,000 donors who are currently deferred. Our analysis suggests that a deferral option focusing on the three highest risk countries would achieve a level of blood safety similar to that achieved by the current policy. © 2016 AABB.

  1. Evaluation of the performance of existing non-laboratory based cardiovascular risk assessment algorithms

    Science.gov (United States)

    2013-01-01

    Background The high burden and rising incidence of cardiovascular disease (CVD) in resource constrained countries necessitates implementation of robust and pragmatic primary and secondary prevention strategies. Many current CVD management guidelines recommend absolute cardiovascular (CV) risk assessment as a clinically sound guide to preventive and treatment strategies. Development of non-laboratory based cardiovascular risk assessment algorithms enable absolute risk assessment in resource constrained countries. The objective of this review is to evaluate the performance of existing non-laboratory based CV risk assessment algorithms using the benchmarks for clinically useful CV risk assessment algorithms outlined by Cooney and colleagues. Methods A literature search to identify non-laboratory based risk prediction algorithms was performed in MEDLINE, CINAHL, Ovid Premier Nursing Journals Plus, and PubMed databases. The identified algorithms were evaluated using the benchmarks for clinically useful cardiovascular risk assessment algorithms outlined by Cooney and colleagues. Results Five non-laboratory based CV risk assessment algorithms were identified. The Gaziano and Framingham algorithms met the criteria for appropriateness of statistical methods used to derive the algorithms and endpoints. The Swedish Consultation, Framingham and Gaziano algorithms demonstrated good discrimination in derivation datasets. Only the Gaziano algorithm was externally validated where it had optimal discrimination. The Gaziano and WHO algorithms had chart formats which made them simple and user friendly for clinical application. Conclusion Both the Gaziano and Framingham non-laboratory based algorithms met most of the criteria outlined by Cooney and colleagues. External validation of the algorithms in diverse samples is needed to ascertain their performance and applicability to different populations and to enhance clinicians’ confidence in them. PMID:24373202

  2. EVALUATING KEY ENVIRONMENTAL RISK FACTORS FOR POLLUTION AT INTERNATIONAL PORTS IN TAIWAN

    Directory of Open Access Journals (Sweden)

    Kuan-Hao Chang

    2017-01-01

    Full Text Available The main purpose of this paper is to use the fuzzy analytic hierarchy process (FAHP approach to evaluate the key environmental risk factors for pollution at international ports in Taiwan. Relying on the literature and experts’ opinions, a hierarchical structure with three risk aspects and thirteen risk factors is first constructed, and a FAHP model then proposed. Based on data from the AHP experts’ questionnaires, we use the FAHP approach to determine key environmental risk factors. Finally, the results show that: (1 Air pollution is the most important aspect of environmental pollution at international ports in Taiwan. (2 In order of relative importance, the top five key environmental risk factors for pollution at international ports in Taiwan are the oil leaks from ships, volatile organic compounds (VOCs, exhaust emissions from ships at berth, harmful coatings on ships' hulls, and ships' failure to use low-pollution fuel. Furthermore, some discussions are provided for port authority in Taiwan.

  3. Committee to evaluate Sandia`s risk expertise: Final report. Volume 1: Presentations

    Energy Technology Data Exchange (ETDEWEB)

    Dudley, E.C.

    1998-05-01

    On July 1--2, 1997, Sandia National Laboratories hosted the External Committee to Evaluate Sandia`s Risk Expertise. Under the auspices of SIISRS (Sandia`s International Institute for Systematic Risk Studies), Sandia assembled a blue-ribbon panel of experts in the field of risk management to assess their risk programs labs-wide. Panelists were chosen not only for their own expertise, but also for their ability to add balance to the panel as a whole. Presentations were made to the committee on the risk activities at Sandia. In addition, a tour of Sandia`s research and development programs in support of the US Nuclear Regulatory Commission was arranged. The panel attended a poster session featuring eight presentations and demonstrations for selected projects. Overviews and viewgraphs from the presentations are included in Volume 1 of this report. Presentations are related to weapons, nuclear power plants, transportation systems, architectural surety, environmental programs, and information systems.

  4. [Evaluation of Suicide Risk Levels in Hospitals: Validity and Reliability Tests].

    Science.gov (United States)

    Macagnino, Sandro; Steinert, Tilman; Uhlmann, Carmen

    2018-05-01

    Examination of in-hospital suicide risk levels concerning their validity and their reliability. The internal suicide risk levels were evaluated in a cross sectional study of in 163 inpatients. A reliability check was performed via determining interrater-reliability of senior physician, therapist and the responsible nurse. Within the scope of the validity check, we conducted analyses of criterion validity and construct validity. For the total sample an "acceptable" to "good" interrater-reliability (Kendalls W = .77) of suicide risk levels were obtained. Schizophrenic disorders showed the lowest values, for personality disorders we found the highest level of interrater-reliability. When examining the criterion validity, Item-9 of the BDI-II is substantial correlated to our suicide risk levels (ρ m  = .54, p validity check, affective disorders showed the highest correlation (ρ = .77), compatible also with "convergent validity". They differed with schizophrenic disorders which showed the least concordance (ρ = .43). In-hospital suicide risk levels may represent an important contribution to the assessment of suicidal behavior of inpatients experiencing psychiatric treatment due to their overall good validity and reliability. © Georg Thieme Verlag KG Stuttgart · New York.

  5. Depression evaluation in an attendance group for high-risk pregnant women

    OpenAIRE

    Adriana Said Daher Baptista; Makilim Nunes Baptista

    2005-01-01

    The goal of this study was to verify the variation of depression symptomatology in an informative high-risk post-partum group of pregnant (GAGER). Six high-risk pregnant women, from a University Hospital participated in this research, and they were evaluated four times: first, before forming the group; second, after two participations in this group; third, 24 to 36 hours after partum; and, four weeks post-partum. The instruments used were a Psychological Clinic Interview and, the Edinburgh Po...

  6. An attempt to evaluate the risks associated with radiological terror

    International Nuclear Information System (INIS)

    Paschoa, A.S.; Dantas, B.M.

    2014-01-01

    The evaluation of the risk of a terrorist attack has been made frequently by multiplying the probability of occurrence of a terrorist attempt by the probability of its success and a quantity which represents the consequences of a successful attack. In the case of a radiological attack the consequences will vary in case the action will be active or passive. Thirteen radionuclides were examined for their potential uses in credible threats or terrorist attacks based on their availability from laboratories and hospitals. Taking into account the dose conversion coefficients published by the International Atomic Energy Agency, those radionuclides with higher dose effectiveness for ingestion are the following: 210 Po; 226 Ra and 241 Am. Other radionuclides which can be used in threats and terror attacks, like 137 Cs for example have also been examined. The risks associated with the selected radionuclides have been tentatively ranked as high, medium, or low. The probability used to evaluate risks depends on the motivation of the terrorist and the capacity, which implies availability or the actual possibility of obtaining a particular radionuclide. On the other hand, whenever a list of radionuclides to be used in a malevolent action is available to a terrorist, the choice of the most adequate will depend also on the action to be undertaken. This work ranks risks associated with radiological terror based on physical, chemical, radio-toxicological and other relevant data on radionuclides, which were either already used in terror attacks, or were pointed out as adequate to be used in such malevolent actions. (author)

  7. Nuclear power plant risk assembly and decomposition for risk management

    International Nuclear Information System (INIS)

    Iden, D.C.

    1985-01-01

    The state-of-the-art method for analyzing the risk from nuclear power plants is probabilistic risk assessment (PRA). The intermediate results of a PRA are first assembled to quantify the risk from operating a nuclear power plant in the form of (1) core damage (or core melt) frequency, (2) plant damage state frequencies, (3) release category frequencies, and (4) the frequency of exceeding specific levels of offsite consequences. Once the overall PRA results have been quantified, the next step is to decompose those results into the individual contributors to each of the four forms of risk in some rank order. The way in which the PRA model is set up to assemble and decompose the plant risk determines the ease and usefulness of the PRA model as a risk management tool for evaluating perturbations to the PRA model. These perturbations can take the form of technical specification changes, hardware modifications, procedural changes, etc. The matrix formalism developed by Dr. Stan Kaplan for risk assembly and decomposition represents a significant breakthrough in making the PRA model an effective risk management tool. The key to understanding the matrix formalism and making it a useful tool for managing nuclear power plant risk is the structure of the PRA model. PRA risk model structure and decomposition of the risk results are discussed with the Seabrook PRA as an example

  8. Chemical risk evaluation, importance of the risk analysis framework uses: Latin America development restrictions

    International Nuclear Information System (INIS)

    Carrillo, M.

    2013-01-01

    The power point presentation is about reach and results of the risk analysis in Venezuela, chemical dangers in food, human damage, injuries , technologies news in fodd development, toxicity, microbiological risk, technical recommendations

  9. Evaluation of effective dose and excess lifetime cancer risk from ...

    African Journals Online (AJOL)

    Evaluation of effective dose and excess lifetime cancer risk from indoor and outdoor gamma dose rate of university of Port Harcourt Teaching Hospital, Rivers State. ... Therefore, the management of University of Port Harcourt teaching hospital ...

  10. An integrated risk assessment approach: Risk assessment in the programmatic environmental impact statement

    International Nuclear Information System (INIS)

    Morris, J.M.

    1994-01-01

    The following paper is an informal summary of salient points made in the presentation entitled open-quotes An Integrated Risk Assessment Approach: Risk Assessment in the Programmatic Environmental Impact Statement (PEIS).close quotes. This presentation was given at the U.S. DOE Integrated Planning Workshop in Denver, Colorado on June 2, 1994. Integrated decision analysis is very important in environmental restoration and waste management in the evaluation of such things as land use planning, waste load forecasting, cost analyses, and technology development activities. Integrated risk assessment is an approach that addresses multiple components of risk, including: risks from surplus facilities as well as typical environmental restoration sites, risks to the public, risks to workers, ecological risk, risks before, during and after remediation activities, and others

  11. Investment risk evaluation techniques: use in energy-intensive industries and implications for ERDA's Industrial Conservation Program

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-07-13

    The trade-off between risk and rate-of-return in investment evaluations is crucial in assessing the commercial potential of future energy-conservation technologies. The focus of the Industrial Conservation Program at ERDA is to reduce the perceived risks of a given technology to the extent that the private sector will adopt the technology within the normal course of its business operations. These perceived risks may emanate from technical, institutional, or commercial uncertainties, or in many cases they may result merely from a company's or industry's lack of previous experience with a particular technology. Regardless of the source of the risk surrounding a project, the uncertainty it poses to the private sector will serve to inhibit decisions to invest. This study evaluates the treatment of risk in capital investments in certain energy-intensive industries which are the primary targets of ERDA's Industrial Conservation Program. These risks evaluation considerations were placed within a context that includes capital budgeting practices and procedures, organizational considerations, and basic rate-of-return evaluation procedures in the targeted energy-intensive industries (petroleum, chemicals, paper, textiles, cement, food processing, aluminum, steel, glass, and agriculture).

  12. Risk evaluation for protection of the public in radiation accidents

    International Nuclear Information System (INIS)

    1967-01-01

    Evaluation of the risk that would be involved in the exposure of the public in the event of a radiation accident requires information on the biological consequences expected of such an exposure. This report defines a range of reference doses of radiation and their corresponding risks to the public in the event of a radiation accident. The reference doses and the considerations on which they were based will be used for assessing the hazards of nuclear installations and for policy decisions by the authorities responsible for measures taken to safeguards the public in the case of a nuclear accident.

  13. Risk assessment in the field of energy

    International Nuclear Information System (INIS)

    Berg, M.; Erdmann, G.; Leist, A.; Renn, O.; Schaber, P.; Scheringer, M.; Seiler, H.; Wiedenmann, R.

    1995-01-01

    The following subjects are dealt with in this book: - ethical thoughts on damage, risks and uncertainty, - risk evaluation from the point of view of sociology, - risk evaluation in the economy, - risk evaluation in law, - environmental damage due to the operation of energy generating systems. figs., tabs., refs

  14. Risk assessment of supply chain for pharmaceutical excipients with AHP-fuzzy comprehensive evaluation.

    Science.gov (United States)

    Li, Maozhong; Du, Yunai; Wang, Qiyue; Sun, Chunmeng; Ling, Xiang; Yu, Boyang; Tu, Jiasheng; Xiong, Yerong

    2016-04-01

    As the essential components in formulations, pharmaceutical excipients directly affect the safety, efficacy, and stability of drugs. Recently, safety incidents of pharmaceutical excipients posing seriously threats to the patients highlight the necessity of controlling the potential risks. Hence, it is indispensable for the industry to establish an effective risk assessment system of supply chain. In this study, an AHP-fuzzy comprehensive evaluation model was developed based on the analytic hierarchy process and fuzzy mathematical theory, which quantitatively assessed the risks of supply chain. Taking polysorbate 80 as the example for model analysis, it was concluded that polysorbate 80 for injection use is a high-risk ingredient in the supply chain compared to that for oral use to achieve safety application in clinic, thus measures should be taken to control and minimize those risks.

  15. Using a familiar risk comparison within a risk ladder to improve risk understanding by low numerates: a study of visual attention.

    Science.gov (United States)

    Keller, Carmen

    2011-07-01

    Previous experimental research provides evidence that a familiar risk comparison within a risk ladder is understood by low- and high-numerate individuals. It especially helps low numerates to better evaluate risk. In the present study, an eye tracker was used to capture individuals' visual attention to a familiar risk comparison, such as the risk associated with smoking. Two parameters of information processing-efficiency and level-were derived from visual attention. A random sample of participants from the general population (N= 68) interpreted a given risk level with the help of the risk ladder. Numeracy was negatively correlated with overall visual attention on the risk ladder (r(s) =-0.28, p= 0.01), indicating that the lower the numeracy, the more the time spent looking at the whole risk ladder. Numeracy was positively correlated with the efficiency of processing relevant frequency (r(s) = 0.34, p improving risk communication formats. © 2011 Society for Risk Analysis.

  16. Risk evaluations of transuranic waste at the Idaho National Engineering Laboratory

    International Nuclear Information System (INIS)

    Smith, T.H.; Keneshea, F.J.

    1980-01-01

    Approximately 75% of the defense low-level transuranic (TRU) waste stored in the United States and 25% of the buried TRU waste is located at the Idaho National Engineering Laboratory (INEL). Studies have been performed to identify and evaluate technical alternatives for the long-term management of this waste. (The alternatives range from leaving the waste in place as is to reviewing, processing, and shipping it to an offsite geological repository.) Among the evalations that have been performed were preliminary risk evaluations. The dose commitment and risk of hypothetical, near-term, accidental or uncontrolled releases of radionuclides have been evaluated for each alternative. The following potential causes of radionuclide release have been studied: process and handling accidents, shipping accidents, natural events (e.g., earthquakes), man-caused events (e.g., airplane crashes), and future intrusion by individuals or small populations after loss of societal control over the waste. The hypothetical releases have been evaluated, in terms of dose commitment and (if pertinent) probability and risk, for all operational steps making up each concept. The dominant scanerios in terms of near-term risk are (1) lava flow up through or over the waste, leading to airbone releases; (2) an explosion or a criticality accident in the waste-processing facility; and (3) a tornado strike or a fire during waste retrieval. The dominant long-term releases are (1) volcanic action; and (2) intrusion of people on the waste site.Although substantial dose commitments to individual members of the public were calculated for the lava flow and intrusion scenarios, no prompt health effects would be expected from the exposures. The effects would be in the form of a slightly increased likelihood of latent cancer induction

  17. [Chemical risk in farming].

    Science.gov (United States)

    Moretto, Angelo

    2013-01-01

    The most important chemical risks in agriculture are plant protection products. Exposure evaluation in agriculture is not an easy task and cannot be carried out with the tools and methodologies of industrial exposures. However, toxicological studies on plant protection products, that are compulsory, provide a lot of useful information for actual risk assessment. Exposure evaluation can be carried out on the basis of exposure models and on semiquantitative measures based on the observation of the activity as it is carried our by the farmer. It is therefore possible to develop risk profiles that can guide exposure evaluation and health surveillance. Concentrated animal feeding operations are associated with several chemical risks including disinfectants, antibiotics, and gases such as ammonia and hydrogen sulfide, in addition to organic dusts and endotoxins.

  18. Developing and evaluating polygenic risk prediction models for stratified disease prevention.

    Science.gov (United States)

    Chatterjee, Nilanjan; Shi, Jianxin; García-Closas, Montserrat

    2016-07-01

    Knowledge of genetics and its implications for human health is rapidly evolving in accordance with recent events, such as discoveries of large numbers of disease susceptibility loci from genome-wide association studies, the US Supreme Court ruling of the non-patentability of human genes, and the development of a regulatory framework for commercial genetic tests. In anticipation of the increasing relevance of genetic testing for the assessment of disease risks, this Review provides a summary of the methodologies used for building, evaluating and applying risk prediction models that include information from genetic testing and environmental risk factors. Potential applications of models for primary and secondary disease prevention are illustrated through several case studies, and future challenges and opportunities are discussed.

  19. Risk management study for the Hanford Site facilities: Risk reduction cost comparison for the retired Hanford Site facilities. Volume 4

    Energy Technology Data Exchange (ETDEWEB)

    Coles, G.A.; Egge, R.G.; Senger, E.; Shultz, M.W.; Taylor, W.E.

    1994-02-01

    This document provides a cost-comparison evaluation for implementing certain risk-reduction measures and their effect on the overall risk of the 100 and 200 Area retired, surplus facilities. The evaluation is based on conditions that existed at the time the risk evaluation team performed facility investigations, and does not acknowledge risk-reduction measures that occurred soon after risk identification. This evaluation is one part of an overall risk management study for these facilities. The retired facilities investigated for this evaluation are located in the 100 and 200 Areas of the 1450-km{sup 2} Hanford Site. The Hanford Site is a semiarid tract of land in southeastern Washington State. The nearest population center is Richland, Washington, (population 32,000) 30 km southeast of the 200 Area. This cost-comparison evaluation (1) determines relative costs for reducing risk to acceptable levels; (2) compares the cost of reducing risk using different risk-reduction options; and (3) compares the cost of reducing risks at different facilities. The result is an identification of the cost effective risk-reduction measures. Supporting information required to develop costs of the various risk-reduction options also is included.

  20. High-Risk List

    Science.gov (United States)

    2017-01-01

    economy. The World Bank has said that “corruption creates an unfavorable business environment by undermining the operation efficiency of firms and... Bank Began as ‘Ponzi Scheme,’” 11/27/2012. 64 Independent Joint Anti-Corruption Monitoring and Evaluation Committee, Unfinished Business : The Follow...HIGH RISK AREA 7: Oversight 51 HIGH-RISK AREA 8: Strategy and Planning 55 CONCLUSION HIGH RISK LIST I JANUARY 11, 2017 2 EXECUTIVE SUMMARY

  1. Evaluating the Risk of Child Abuse: The Child Abuse Risk Assessment Scale (CARAS)

    Science.gov (United States)

    Chan, Ko Ling

    2012-01-01

    The present study developed the Child Abuse Risk Assessment Scale (CARAS), an actuarial instrument for the assessment of the risk of physical child abuse. Data of 2,363 Chinese parents (47.7% male) living in Hong Kong were used in the analyses. Participants were individually interviewed with a questionnaire assessing their perpetration of child…

  2. A unified framework for evaluating the risk of re-identification of text de-identification tools.

    Science.gov (United States)

    Scaiano, Martin; Middleton, Grant; Arbuckle, Luk; Kolhatkar, Varada; Peyton, Liam; Dowling, Moira; Gipson, Debbie S; El Emam, Khaled

    2016-10-01

    It has become regular practice to de-identify unstructured medical text for use in research using automatic methods, the goal of which is to remove patient identifying information to minimize re-identification risk. The metrics commonly used to determine if these systems are performing well do not accurately reflect the risk of a patient being re-identified. We therefore developed a framework for measuring the risk of re-identification associated with textual data releases. We apply the proposed evaluation framework to a data set from the University of Michigan Medical School. Our risk assessment results are then compared with those that would be obtained using a typical contemporary micro-average evaluation of recall in order to illustrate the difference between the proposed evaluation framework and the current baseline method. We demonstrate how this framework compares against common measures of the re-identification risk associated with an automated text de-identification process. For the probability of re-identification using our evaluation framework we obtained a mean value for direct identifiers of 0.0074 and a mean value for quasi-identifiers of 0.0022. The 95% confidence interval for these estimates were below the relevant thresholds. The threshold for direct identifier risk was based on previously used approaches in the literature. The threshold for quasi-identifiers was determined based on the context of the data release following commonly used de-identification criteria for structured data. Our framework attempts to correct for poorly distributed evaluation corpora, accounts for the data release context, and avoids the often optimistic assumptions that are made using the more traditional evaluation approach. It therefore provides a more realistic estimate of the true probability of re-identification. This framework should be used as a basis for computing re-identification risk in order to more realistically evaluate future text de-identification tools

  3. Risk Analysis Based on AHP and Fuzzy Comprehensive Evaluation for Maglev Train Bogie

    OpenAIRE

    Fan, Chengxin; Dou, Fengshan; Tong, Baiming; Long, Zhiqiang

    2016-01-01

    The maglev bogie is the key subsystem for maglev train security. To ensure life and property security, it is essential to evaluate its risk level before its operation. In this paper, a combinational method of analytic hierarchy process and fuzzy comprehensive evaluation is proposed to assess hazards in a complex maglev bogie system associated with multiple subsystems’ failures. The very comprehensive identification of risk sources has been done by analyzing the structure of maglev bogie. Furt...

  4. Transport project evaluation: feasibility risk assessment and scenario forecasting

    DEFF Research Database (Denmark)

    Salling, Kim Bang; Leleur, Steen

    2017-01-01

    This paper presents a new approach to transport project assessment in terms of feasibility risk assessment and reference class forecasting. Conventionally, transport project assessment is based upon a Cost-Benefit Analysis (CBA) where evaluation criteria such as Benefit Cost Ratios (BCR...... on the preliminary construction cost estimates. Hereafter, a quantitative risk analysis is provided making use of Monte Carlo simulation. This approach facilitates random input parameters based upon reference class forecasting, hence, a parameter data fit has been performed in order to obtain validated probability...... Scenario Forecasting (RSF) frame. The RSF is anchored in the cost-benefit analysis; thus, it provides decision-makers with a quantitative mean of assessing the transport infrastructure project. First, the RSF method introduces uncertainties within the CBA by applying Optimism Bias uplifts...

  5. Risk evaluation in Columbian electricity market using fuzzy logic

    International Nuclear Information System (INIS)

    Medina, S.; Moreno, J.

    2007-01-01

    This article proposes a model based on Fuzzy Logic to evaluate the market risk that a trading agent faces in the electric power negotiation in Colombia, as part of a general model of negotiation. The proposed model considers single external factors as regulatory changes, social and political issues, and the condition of the national transmission net. Variables of the market associated to these risk factors were selected and some graphic and statistical analyses were made in order to check their relationship with the electricity prices and to determine why the experts consider these factors in their analyses. According to the obtained results a Mamdani Fuzzy Inference System which contains the expert knowledge was developed and it is presented in a fuzzy cognitive map. (author)

  6. EVALUATING RISK-PREDICTION MODELS USING DATA FROM ELECTRONIC HEALTH RECORDS.

    Science.gov (United States)

    Wang, L E; Shaw, Pamela A; Mathelier, Hansie M; Kimmel, Stephen E; French, Benjamin

    2016-03-01

    The availability of data from electronic health records facilitates the development and evaluation of risk-prediction models, but estimation of prediction accuracy could be limited by outcome misclassification, which can arise if events are not captured. We evaluate the robustness of prediction accuracy summaries, obtained from receiver operating characteristic curves and risk-reclassification methods, if events are not captured (i.e., "false negatives"). We derive estimators for sensitivity and specificity if misclassification is independent of marker values. In simulation studies, we quantify the potential for bias in prediction accuracy summaries if misclassification depends on marker values. We compare the accuracy of alternative prognostic models for 30-day all-cause hospital readmission among 4548 patients discharged from the University of Pennsylvania Health System with a primary diagnosis of heart failure. Simulation studies indicate that if misclassification depends on marker values, then the estimated accuracy improvement is also biased, but the direction of the bias depends on the direction of the association between markers and the probability of misclassification. In our application, 29% of the 1143 readmitted patients were readmitted to a hospital elsewhere in Pennsylvania, which reduced prediction accuracy. Outcome misclassification can result in erroneous conclusions regarding the accuracy of risk-prediction models.

  7. Rituals in risk evaluation for land-use planning

    NARCIS (Netherlands)

    Xanten, van N.H.W.; Pietersen, C.M.; Pasman, H.J.; Vrijling, H.K.; Kerstens, J.G.M.

    2013-01-01

    In Dutch external safety policy, the acceptance of risk for the population in areas surrounding hazardous substances establishments is based on a limit value for individual risk (IR). Additionally, changes to societal risk (SR) must be justified. A specific software program (SAFETI-NL) with the

  8. Metal Vapor Arcing Risk Assessment Tool

    Science.gov (United States)

    Hill, Monika C.; Leidecker, Henning W.

    2010-01-01

    The Tin Whisker Metal Vapor Arcing Risk Assessment Tool has been designed to evaluate the risk of metal vapor arcing and to help facilitate a decision toward a researched risk disposition. Users can evaluate a system without having to open up the hardware. This process allows for investigating components at risk rather than spending time and money analyzing every component. The tool points to a risk level and provides direction for appropriate action and documentation.

  9. Risk as a social phenomenon.

    Science.gov (United States)

    Jamison, Wesley V

    2003-01-01

    What do nuclear power, smoking, and eating beef have in common? The answer is multifaceted. They all share aspects of mass production and consumption, and therefore consumer confidence comes into play in evaluating each of the products' merits. They all produce some level of anxiety--be it in response to adverse media coverage, or the successes of adversarial interest groups in publicizing those products' weaknesses--among consumers who wonder what if any level of the product should be consumed. Finally, nuclear power, smoking, and eating beef all share risk; that is, the perceived and real detriments of producing and consuming those products. Whether or not the associated risks--from increased cancer to increased heart disease--are real is beside the point. When talking about risk, scientific education must deal with the perception of risk as much as its reality. Risk is a socially defined phenomenon, and as such, the successful scientists/communicator must understand the social evaluations of it. While many scientists take a rational view of risk evaluation and consumers often make rational decisions about technological and scientific risk based upon the costs and benefits of that technology, this approach is problematic for three reasons. First, the nature of modern risks has changed in that risk is complex, incomprehensible and uncontrollable to the average person. Second, the rational approach assumes that all costs and benefits of a technology, both real and potential, both current and future, can be known and therefore rationally evaluated. This is not the case. Third, evidence from Europe indicates that trust in information sources about risk has fallen, and thus classic scientific education campaigns that rely upon increasing public knowledge and acceptance of technological and scientific risk are problematic. Because of these factors we argue that effective scientific response must begin to understand the social components of risk if campaigns to shape

  10. A framework and case studies for evaluation of enzyme ontogeny in children's health risk evaluation.

    Science.gov (United States)

    Ginsberg, Gary; Vulimiri, Suryanarayana V; Lin, Yu-Sheng; Kancherla, Jayaram; Foos, Brenda; Sonawane, Babasaheb

    2017-01-01

    Knowledge of the ontogeny of Phase I and Phase II metabolizing enzymes may be used to inform children's vulnerability based upon likely differences in internal dose from xenobiotic exposure. This might provide a qualitative assessment of toxicokinetic (TK) variability and uncertainty pertinent to early lifestages and help scope a more quantitative physiologically based toxicokinetic (PBTK) assessment. Although much is known regarding the ontogeny of metabolizing systems, this is not commonly utilized in scoping and problem formulation stage of human health risk evaluation. A framework is proposed for introducing this information into problem formulation which combines data on enzyme ontogeny and chemical-specific TK to explore potential child/adult differences in internal dose and whether such metabolic differences may be important factors in risk evaluation. The framework is illustrated with five case study chemicals, including some which are data rich and provide proof of concept, while others are data poor. Case studies for toluene and chlorpyrifos indicate potentially important child/adult TK differences while scoping for acetaminophen suggests enzyme ontogeny is unlikely to increase early-life risks. Scoping for trichloroethylene and aromatic amines indicates numerous ways that enzyme ontogeny may affect internal dose which necessitates further evaluation. PBTK modeling is a critical and feasible next step to further evaluate child-adult differences in internal dose for a number of these chemicals.

  11. Systematic Review of Health Economic Impact Evaluations of Risk Prediction Models : Stop Developing, Start Evaluating

    NARCIS (Netherlands)

    van Giessen, Anoukh; Peters, Jaime; Wilcher, Britni; Hyde, Chris; Moons, Carl; de Wit, Ardine; Koffijberg, Erik

    2017-01-01

    Background: Although health economic evaluations (HEEs) are increasingly common for therapeutic interventions, they appear to be rare for the use of risk prediction models (PMs). Objectives: To evaluate the current state of HEEs of PMs by performing a comprehensive systematic review. Methods: Four

  12. Fuzzy Risk Evaluation in Failure Mode and Effects Analysis Using a D Numbers Based Multi-Sensor Information Fusion Method.

    Science.gov (United States)

    Deng, Xinyang; Jiang, Wen

    2017-09-12

    Failure mode and effect analysis (FMEA) is a useful tool to define, identify, and eliminate potential failures or errors so as to improve the reliability of systems, designs, and products. Risk evaluation is an important issue in FMEA to determine the risk priorities of failure modes. There are some shortcomings in the traditional risk priority number (RPN) approach for risk evaluation in FMEA, and fuzzy risk evaluation has become an important research direction that attracts increasing attention. In this paper, the fuzzy risk evaluation in FMEA is studied from a perspective of multi-sensor information fusion. By considering the non-exclusiveness between the evaluations of fuzzy linguistic variables to failure modes, a novel model called D numbers is used to model the non-exclusive fuzzy evaluations. A D numbers based multi-sensor information fusion method is proposed to establish a new model for fuzzy risk evaluation in FMEA. An illustrative example is provided and examined using the proposed model and other existing method to show the effectiveness of the proposed model.

  13. Threshold Evaluation of Emergency Risk Communication for Health Risks Related to Hazardous Ambient Temperature.

    Science.gov (United States)

    Liu, Yang; Hoppe, Brenda O; Convertino, Matteo

    2018-04-10

    Emergency risk communication (ERC) programs that activate when the ambient temperature is expected to cross certain extreme thresholds are widely used to manage relevant public health risks. In practice, however, the effectiveness of these thresholds has rarely been examined. The goal of this study is to test if the activation criteria based on extreme temperature thresholds, both cold and heat, capture elevated health risks for all-cause and cause-specific mortality and morbidity in the Minneapolis-St. Paul Metropolitan Area. A distributed lag nonlinear model (DLNM) combined with a quasi-Poisson generalized linear model is used to derive the exposure-response functions between daily maximum heat index and mortality (1998-2014) and morbidity (emergency department visits; 2007-2014). Specific causes considered include cardiovascular, respiratory, renal diseases, and diabetes. Six extreme temperature thresholds, corresponding to 1st-3rd and 97th-99th percentiles of local exposure history, are examined. All six extreme temperature thresholds capture significantly increased relative risks for all-cause mortality and morbidity. However, the cause-specific analyses reveal heterogeneity. Extreme cold thresholds capture increased mortality and morbidity risks for cardiovascular and respiratory diseases and extreme heat thresholds for renal disease. Percentile-based extreme temperature thresholds are appropriate for initiating ERC targeting the general population. Tailoring ERC by specific causes may protect some but not all individuals with health conditions exacerbated by hazardous ambient temperature exposure. © 2018 Society for Risk Analysis.

  14. Risk-based cost-benefit analysis for evaluating microbial risk mitigation in a drinking water system.

    Science.gov (United States)

    Bergion, Viktor; Lindhe, Andreas; Sokolova, Ekaterina; Rosén, Lars

    2018-04-01

    Waterborne outbreaks of gastrointestinal diseases can cause large costs to society. Risk management needs to be holistic and transparent in order to reduce these risks in an effective manner. Microbial risk mitigation measures in a drinking water system were investigated using a novel approach combining probabilistic risk assessment and cost-benefit analysis. Lake Vomb in Sweden was used to exemplify and illustrate the risk-based decision model. Four mitigation alternatives were compared, where the first three alternatives, A1-A3, represented connecting 25, 50 and 75%, respectively, of on-site wastewater treatment systems in the catchment to the municipal wastewater treatment plant. The fourth alternative, A4, represented installing a UV-disinfection unit in the drinking water treatment plant. Quantitative microbial risk assessment was used to estimate the positive health effects in terms of quality adjusted life years (QALYs), resulting from the four mitigation alternatives. The health benefits were monetised using a unit cost per QALY. For each mitigation alternative, the net present value of health and environmental benefits and investment, maintenance and running costs was calculated. The results showed that only A4 can reduce the risk (probability of infection) below the World Health Organization guidelines of 10 -4 infections per person per year (looking at the 95th percentile). Furthermore, all alternatives resulted in a negative net present value. However, the net present value would be positive (looking at the 50 th percentile using a 1% discount rate) if non-monetised benefits (e.g. increased property value divided evenly over the studied time horizon and reduced microbial risks posed to animals), estimated at 800-1200 SEK (€100-150) per connected on-site wastewater treatment system per year, were included. This risk-based decision model creates a robust and transparent decision support tool. It is flexible enough to be tailored and applied to local

  15. Risk decisions and nuclear waste

    International Nuclear Information System (INIS)

    Hansson, S.O.

    1987-11-01

    The risk concept is multidimensional, and much of its contents is lost in the conventional reduction to a unidimensional and quantifiable term. Eight major dimensions of the risk concept are discussed, among them the time factor and the lack-of-knowledge factor. The requirements of a rational discourse are discussed, in general and in relation to risk issues. It is concluded that no single method for the comparison and assessment of risks can be seen as the only rational method. Different methods can all be rational, although based on different values. Risk evaluations cannot be performed as expert assessments, divorced from the political decision process. Instead, risk evaluation must be seen as an essentially political process. Public participation is necessary in democratic decision-making on risks as well as on other issues. Important conclusions can be drawn for the management of nuclear waste, concerning specifications for the technical solution, the need for research on risk concepts, and the decision-making process. (orig.)

  16. Assessing older drivers: a primary care protocol to evaluate driving safety risk.

    Science.gov (United States)

    Murden, Robert A; Unroe, Kathleen

    2005-08-01

    Most articles on elder drivers offer either general advice, or review testing protocols that divide drivers into two distinct groups: safe or unsafe. We believe it is unreasonable to expect any testing to fully separate drivers into just these two mutually exclusive groups, so we offer a protocol for a more practical approach. This protocol can be applied by primary care physicians. We review the justification for the many steps of this protocol, which have branches that lead to identifying drivers as low risk, high risk (for accidents) or needing further evaluation. Options for further evaluation are provided.

  17. Risk management in customs control

    OpenAIRE

    Drobot, Elena; Klevleeva, Aziza

    2016-01-01

    The particularities of risk-management system implementation within customs control are discussed in the article. The authors single out the elements of risk-management system, evaluate effectiveness of risk-management in customs control. The main reasons for non-implementation of risk-management system in customs control are described, as well. Particular attention is paid to the benefits of customs risk management.

  18. Fuzzy comprehensive evaluation-based disaster risk assessment of desertification in Horqin Sand Land, China.

    Science.gov (United States)

    Wang, Yongfang; Zhang, Jiquan; Guo, Enliang; Sun, Zhongyi

    2015-02-03

    Desertification is a typical disaster risk event in which human settlements and living environments are destroyed. Desertification Disaster Risk Assessment can control and prevent the occurrence and development of desertification disasters and reduce their adverse influence on human society. This study presents the methodology and procedure for risk assessment and zoning of desertification disasters in Horqin Sand Land. Based on natural disaster risk theory and the desertification disaster formation mechanism, the Desertification Disaster Risk Index (DDRI) combined hazard, exposure, vulnerability and restorability factors and was developed mainly by using multi-source data and the fuzzy comprehensive evaluation method. The results showed that high risk and middle risk areas account for 28% and 23% of the study area, respectively. They are distributed with an "S" type in the study area. Low risk and very low risk areas account for 21% and 10% of the study area, respectively. They are distributed in the west-central and southwestern parts. Very high risk areas account for 18% of the study area and are distributed in the northeastern parts. The results can be used to know the desertification disaster risk level. It has important theoretical and practical significance to prevention and control of desertification in Horqin Sand Land and even in Northern China.

  19. Fuzzy Comprehensive Evaluation-Based Disaster Risk Assessment of Desertification in Horqin Sand Land, China

    Directory of Open Access Journals (Sweden)

    Yongfang Wang

    2015-02-01

    Full Text Available Desertification is a typical disaster risk event in which human settlements and living environments are destroyed. Desertification Disaster Risk Assessment can control and prevent the occurrence and development of desertification disasters and reduce their adverse influence on human society. This study presents the methodology and procedure for risk assessment and zoning of desertification disasters in Horqin Sand Land. Based on natural disaster risk theory and the desertification disaster formation mechanism, the Desertification Disaster Risk Index (DDRI combined hazard, exposure, vulnerability and restorability factors and was developed mainly by using multi-source data and the fuzzy comprehensive evaluation method. The results showed that high risk and middle risk areas account for 28% and 23% of the study area, respectively. They are distributed with an “S” type in the study area. Low risk and very low risk areas account for 21% and 10% of the study area, respectively. They are distributed in the west-central and southwestern parts. Very high risk areas account for 18% of the study area and are distributed in the northeastern parts. The results can be used to know the desertification disaster risk level. It has important theoretical and practical significance to prevention and control of desertification in Horqin Sand Land and even in Northern China.

  20. Risk Evaluation of a UHV Power Transmission Construction Project Based on a Cloud Model and FCE Method for Sustainability

    Directory of Open Access Journals (Sweden)

    Huiru Zhao

    2015-03-01

    Full Text Available In order to achieve the sustainable development of energy, Ultra High Voltage (UHV power transmission construction projects are being established in China currently. Their high-tech nature, the massive amount of money involved, and the need for multi-agent collaboration as well as complex construction environments bring many challenges and risks. Risk management, therefore, is critical to reduce the risks and realize sustainable development of projects. Unfortunately, many traditional risk assessment methods may not perform well due to the great uncertainty and randomness inherent in UHV power construction projects. This paper, therefore, proposes a risk evaluation index system and a hybrid risk evaluation model to evaluate the risk of UHV projects and find out the key risk factors. This model based on a cloud model and fuzzy comprehensive evaluation (FCE method combines the superiority of the cloud model for reflecting randomness and discreteness with the advantages of the fuzzy comprehensive evaluation method in handling uncertain and vague issues. For the sake of proving our framework, an empirical study of “Zhejiang-Fuzhou” UHV power transmission construction project is presented. As key contributions, we find the risk of this project lies at a “middle” to “high” level and closer to a “middle” level; the “management risk” and “social risk” are identified as the most important risk factors requiring more attention; and some risk control recommendations are proposed. This article demonstrates the value of our approach in risk identification, which seeks to improve the risk control level and the sustainable development of UHV power transmission construction projects.

  1. Operational risk assessment.

    Science.gov (United States)

    McKim, Vicky L

    2017-06-01

    In the world of risk management, which encompasses the business continuity disciplines, many types of risk require evaluation. Financial risk is most often the primary focus, followed by product and market risks. Another critical area, which typically lacks a thorough review or may be overlooked, is operational risk. This category encompasses many risk exposure types including those around building structures and systems, environmental issues, nature, neighbours, clients, regulatory compliance, network, data security and so on. At times, insurance carriers will assess internal hazards, but seldom do these assessments include more than a cursory look at other types of operational risk. In heavily regulated environments, risk assessments are required but may not always include thorough assessments of operational exposures. Vulnerabilities may linger or go unnoticed, only to become the catalyst for a business disruption at a later time, some of which are so severe that business recovery becomes nearly impossible. Businesses may suffer loss of clients as the result of a prolonged disruption of services. Comprehensive operational risk assessments can assist in identifying such vulnerabilities, exposures and threats so that the risk can be minimised or removed. This paper lays out how an assessment of this type can be successfully conducted.

  2. The Arousing Risk: Influences of positive and negative arousal on preferences for economic risk

    OpenAIRE

    Galentino, Andrea

    2015-01-01

    Standard economic models explain decision making under risk as a utility maximization process. Developments in cognitive psychology and neuroeconomics showed the volatility of such conceptualization highlighting human bounded rationality and discussing the role of decision maker’s affective state (basic reactions to any emotionally charged event) in cognitive evaluation of risk (risk as feeling). In particular, an affective-based evaluation of choice options may determine whether decision mak...

  3. High prevalence of suicide risk in people living with HIV: who is at higher risk?

    Science.gov (United States)

    Passos, Susane Müller Klug; Souza, Luciano Dias de Mattos; Spessato, Bárbara Coiro

    2014-01-01

    A cross-sectional study was developed to evaluate suicide risk and associated factors in HIV/AIDS patients at a regional reference center for the treatment of HIV/AIDS in southern Brazil. We assessed 211 patients in regard to suicide risk, clinical and sociodemographic characteristics, drug use, depression, and anxiety. Suicide risk was assessed with Mini International Neuropsychiatric Interview, Module C. Multivariate analysis was performed using Poisson regression. Of the total sample, 34.1% were at risk of suicide. In the multivariate analysis, the following variables were independently associated with suicide risk: female gender; age up to 47 years; unemployment; indicative of anxiety; indicative of depression; and abuse or addiction on psychoactive substances. Suicide risk is high in this population. Psychosocial factors should be included in the physical and clinical evaluation, given their strong association with suicide risk.

  4. Quality Risk Evaluation of the Food Supply Chain Using a Fuzzy Comprehensive Evaluation Model and Failure Mode, Effects, and Criticality Analysis

    Directory of Open Access Journals (Sweden)

    Libiao Bai

    2018-01-01

    Full Text Available Evaluating the quality risk level in the food supply chain can reduce quality information asymmetry and food quality incidents and promote nationally integrated regulations for food quality. In order to evaluate it, a quality risk evaluation indicator system for the food supply chain is constructed based on an extensive literature review in this paper. Furthermore, a mathematical model based on the fuzzy comprehensive evaluation model (FCEM and failure mode, effects, and criticality analysis (FMECA for evaluating the quality risk level in the food supply chain is developed. A computational experiment aimed at verifying the effectiveness and feasibility of this proposed model is conducted on the basis of a questionnaire survey. The results suggest that this model can be used as a general guideline to assess the quality risk level in the food supply chain and achieve the most important objective of providing a reference for the public and private sectors when making decisions on food quality management.

  5. Two Stage Fuzzy Methodology to Evaluate the Credit Risks of Investment Projects

    OpenAIRE

    O. Badagadze; G. Sirbiladze; I. Khutsishvili

    2014-01-01

    The work proposes a decision support methodology for the credit risk minimization in selection of investment projects. The methodology provides two stages of projects’ evaluation. Preliminary selection of projects with minor credit risks is made using the Expertons Method. The second stage makes ranking of chosen projects using the Possibilistic Discrimination Analysis Method. The latter is a new modification of a well-known Method of Fuzzy Discrimination Analysis.

  6. Fire Risk in MTBF Evaluation for UPS System

    Directory of Open Access Journals (Sweden)

    Stefano Elia

    2016-01-01

    Full Text Available The reliability improvement of no-break redundant electrical systems is the first aim of the proposed strategy. The failure of some UPS (Uninterruptible Power Supply system may lead to the fire occurrence. The most used electrical configurations are presented and discussed in the paper. The innovation of the proposed method consists of taking into account the fire risk to improve the accuracy of wiring configuration and component’s failure rate. Thorough research on MTBF (Mean Time Between Failure data has been performed for each wiring component and UPS. The fire risk is taken into account introducing an equivalent fire block in the Reliability Block Diagram scheme; it has an MTBF value calculated form yearly statistics of UPS fire events. The reliability of the most used UPS electrical configurations is evaluated by means of the RBD method. Different electrical systems have been investigated and compared based on MTBF. The importance of fire compartmentation between two or more UPS’ connected in parallel is proved here.

  7. Dipyridamole-thallium scanning in patients undergoing vascular surgery. Optimizing preoperative evaluation of cardiac risk

    International Nuclear Information System (INIS)

    Eagle, K.A.; Singer, D.E.; Brewster, D.C.; Darling, R.C.; Mulley, A.G.; Boucher, C.A.

    1987-01-01

    Dipyridamole-thallium imaging has been suggested as a method of preoperatively assessing cardiac risk in patients undergoing major surgery. To define more clearly its proper role in preoperative assessment, we prospectively evaluated 111 patients undergoing vascular surgery. In the first set of 61 patients, our data confirmed the value of preoperative dipyridamole-thallium scanning in identifying the patients who suffered postoperative ischemic events. Events occurred in eight of 18 patients with reversible defects on preoperative imaging, compared with no events in 43 patients with no thallium redistribution (confidence interval for the risk difference: 0.624, 0.256). The results also suggested that clinical factors might allow identification of a low-risk subset of patients. To test the hypothesis that patients with no evidence of congestive heart failure, angina, prior myocardial infarction, or diabetes do not require further preoperative testing, we evaluated an additional 50 patients having vascular procedures. None of the 23 without the clinical markers had untoward outcomes, while ten of 27 patients with one or more of these clinical markers suffered postoperative ischemic events (confidence interval for the risk difference: 0.592, 0.148). In the clinical high-risk subset, further risk stratification is achieved with dipyridamole-thallium scanning

  8. Opinions of Nurses About the Evaluation of Risk of Falling Among Inpatients.

    Science.gov (United States)

    Atay, Selma; Vurur, Sevda; Erdugan, Necla

    Patient falls and fall-related injuries are an important problem for patients, relatives, caregivers, and the health system at large. This study aims to identify opinions of nurses about the risk of falling among patients staying in hospitals. This study uses a qualitative descriptive design and employs a semistructured interview method to identify the opinions and experiences of nurses about patient falls. This study evaluated the opinions of a total of 12 staff nurses. It was found that nurses consider patients in the postoperative period to be most prone to falls. They think that most falls take place during transfers and that the medical diagnosis of the patient plays a crucial role in fall incidents. The most important problem associated with patient falls was symptoms of traumatic brain injury. According to the participating nurses, the risk of fall for every patient should be evaluated upon admission. Measures that the nurses take against patient falls include raising the bed's side rails and securing the bed brakes. The findings of this research suggest that in-service training programs about the evaluation of the risk of falling should be organized for nurses. Guidelines should be developed for patients with different levels of risk of falling. It is suggested that nurses should be in charge of training patients who are conscious, their relatives, and caregiver personnel. The training of nurses and caregivers helps to prevent the falls of inpatients.

  9. Risk monitor-a tool for computer aided risk assessment for NPPs

    International Nuclear Information System (INIS)

    Vinod, Gopika; Saraf, R.K.; Babar, A.K.; Kushwaha, H.S.; Hadap, Nikhil

    2001-01-01

    Considerable changes occur in components status and system design and subsequent operation due to changes in plant configuration and their operating procedures. These changes are organised because some components are randomly down and other can be planned for test, maintenance and repair. This results in a fluctuation of risk level over operating time, which is termed as risk profile. Probabilistic Safety Assessment (PSA) is an analytical technique for assessing the risk by integrating diverse aspects of design and operation of a Nuclear Power Plant. Risk can be defined as the product of the probability of an accident and the consequences from that accident. Reactor Safety Division of BARC has developed PC based tool, which can assess the risk profile. This package can be used to optimise the operation in Nuclear Power Plants with respect to a minimum risk level over the operating time, and is termed as Risk Monitor. Risk Monitor is user friendly and can re-evaluate core damage frequency for changes in component status, test interval, initiating event frequency etc. Plant restoration advice, when the plant is in high risk configuration, current status of all plant equipment, and equipment prioritization are also provided by the package. (author)

  10. The care of Filipino juvenile offenders in residential facilities evaluated using the risk-need-responsivity model

    NARCIS (Netherlands)

    Spruit, A.; Wissink, I.B.; Stams, G.J.J.M.

    According to the risk-need-responsivity model of offender, assessment and rehabilitation treatment should target specific factors that are related to re-offending. This study evaluates the residential care of Filipino juvenile offenders using the risk-need-responsivity model. Risk analyses and

  11. Development and validation of a risk model for identification of non-neutropenic, critically ill adult patients at high risk of invasive Candida infection: the Fungal Infection Risk Evaluation (FIRE) Study.

    Science.gov (United States)

    Harrison, D; Muskett, H; Harvey, S; Grieve, R; Shahin, J; Patel, K; Sadique, Z; Allen, E; Dybowski, R; Jit, M; Edgeworth, J; Kibbler, C; Barnes, R; Soni, N; Rowan, K

    2013-02-01

    There is increasing evidence that invasive fungal disease (IFD) is more likely to occur in non-neutropenic patients in critical care units. A number of randomised controlled trials (RCTs) have evaluated antifungal prophylaxis in non-neutropenic, critically ill patients, demonstrating a reduction in the risk of proven IFD and suggesting a reduction in mortality. It is necessary to establish a method to identify and target antifungal prophylaxis at those patients at highest risk of IFD, who stand to benefit most from any antifungal prophylaxis strategy. To develop and validate risk models to identify non-neutropenic, critically ill adult patients at high risk of invasive Candida infection, who would benefit from antifungal prophylaxis, and to assess the cost-effectiveness of targeting antifungal prophylaxis to high-risk patients based on these models. Systematic review, prospective data collection, statistical modelling, economic decision modelling and value of information analysis. Ninety-six UK adult general critical care units. Consecutive admissions to participating critical care units. None. Invasive fungal disease, defined as a blood culture or sample from a normally sterile site showing yeast/mould cells in a microbiological or histopathological report. For statistical and economic modelling, the primary outcome was invasive Candida infection, defined as IFD-positive for Candida species. Systematic review: Thirteen articles exploring risk factors, risk models or clinical decision rules for IFD in critically ill adult patients were identified. Risk factors reported to be significantly associated with IFD were included in the final data set for the prospective data collection. Data were collected on 60,778 admissions between July 2009 and March 2011. Overall, 383 patients (0.6%) were admitted with or developed IFD. The majority of IFD patients (94%) were positive for Candida species. The most common site of infection was blood (55%). The incidence of IFD

  12. 77 FR 41985 - Use of Influenza Disease Models To Quantitatively Evaluate the Benefits and Risks of Vaccines: A...

    Science.gov (United States)

    2012-07-17

    ... models to generate quantitative estimates of the benefits and risks of influenza vaccination. The public...] Use of Influenza Disease Models To Quantitatively Evaluate the Benefits and Risks of Vaccines: A... Influenza Disease Models to Quantitatively Evaluate the Benefits and Risks of Vaccines: A Technical Workshop...

  13. Seismic risk evaluation within the technology neutral framework

    International Nuclear Information System (INIS)

    Johnson, B.C.; Apostolakis, G.E.

    2012-01-01

    Highlights: ► We examine seismic risk within the Technology Neutral Framework (TNF). ► We find that the risk goals in the TNF to be stringent compared with current goals. ► We note that the current fleet reactors would not meet the TNF goals. ► We recommend that an initiating frequency cutoff of 10 −5 per year be use in evaluating seismic risk. - Abstract: The NRC Office of Nuclear Regulatory Research has proposed a risk-informed and performance-based licensing process that is referred to as the technology neutral framework (TNF). In the TNF, licensing basis events (LBEs), determined using probabilistic risk assessment methods, take the place of design basis accidents. These LBEs are constructed by grouping together accident sequences with similar phenomenology. All event sequences with a mean frequency greater than 10 −7 per reactor year are to be considered as part of the licensing basis. Imposing such a limit would require that earthquakes with a mean return period of ten million years be considered as part of the licensing basis. It is difficult to get seismic hazards (i.e., ground accelerations) from expert seismologists at such low frequencies. This is because it is difficult or impossible to confidently say what the seismic hazard might be at these extremely low frequencies. A linear extrapolation in log-log space of hazard curves at the Clinton site down to 10 −7 per year leads to a peak ground acceleration of about 4.5 g. A Weibull distribution is also used to fit the curve leading to a peak ground acceleration of about 2.6 g. These extrapolations demonstrate the extreme nature of rare earthquakes. Even when seismic isolation is implemented, the TNF goal is not met. The problem appears to be that there is no limit on initiating event frequency in the TNF. Demonstrating that a design meets the goals of the TNF would be nearly impossible. A frequency limit for earthquakes could be imposed at a frequency of about 10 −5 per year to focus on

  14. Control of Risks Through the Use of Procedures: A Method for Evaluating the Change in Risk

    Science.gov (United States)

    Praino, Gregory T.; Sharit, Joseph

    2010-01-01

    not. The model used for describing the Failure Likelihood considers how well a task was established by evaluating that task on five components. The components selected to define a well established task are: that it be defined, assigned to someone capable, that they be trained appropriately, that the actions be organized to enable proper completion and that some form of independent monitoring be performed. Validation of the method was based on the information provided by a group of experts in Space Shuttle ground processing when they were presented with 5 scenarios that identified a clause from a procedure. For each scenario, they recorded their perception of how important the associated rule was and how likely it was to fail. They then rated the components of Control Value and Failure Likelihood for all the scenarios. The order in which each reviewer ranked the scenarios Control Value and Failure Likelihood was compared to the order in which they ranked the scenarios for each of the associated components; inevitability and opportunity for Control Value and definition, assignment, training, organization and monitoring for Failure Likelihood. This order comparison showed how the components contributed to a relative relationship to the substitute risk element. With the relationship established for Space Shuttle ground processing, this method can be used to gauge if the introduction or removal of a particular rule will increase or decrease the .risk associated with the hazard it is intended to control.

  15. Evaluation of the radiological risk resulting from road transportation of tritiated water

    International Nuclear Information System (INIS)

    Menossi, C.A.; Segado, R.; Reyes, R.

    1983-01-01

    A probability model for the evaluation of the individual radiological risk resulting from road transportation of tritiated water in 200-liter drums is presented. In order to evaluate such risk, an evaluation must be made of the probability for an individual to be involved in the consequences of a radiological transport accident, to incur a given dose and to suffer deleterious effects resulting from the dose incurred. With the purpose of quantifying the importance of accidents, a severity level classification was adopted as a function of the fraction of liquid volume spilled as a result of the accident. Considering the above-mentioned severity classification and the transported volume, the volume and the spill area are implied, while the soil characteristics are taken into account. By evaluating the spill characteristics, the average meteorological conditions in the area under analysis and the activity concentration of the transported liquid, the activity concentration values for tritium in air may be estimated, thus allowing calculation of the effective dose equivalent to be incurred by the individual who is most exposed to the consequences of an associated event. As a result of the summarized analysis above, a value of the individual risk per unit of activity concentration is obtained for tritium and for a given volume of transported liquid. 8 references

  16. Man, technology and risk: a study on intuitive risk assessment and attitudes towards nuclear energy

    Energy Technology Data Exchange (ETDEWEB)

    Renn, O

    1981-06-01

    Using the instruments of empirical social sciences, a cross-section study was conducted comprising experiments on qualitative risk characteristics, in-depth interviews on mechanisms of risk perception and representative surveys of the public on technical risk sources, in particular with regard to nuclear energy. The results of these studies show that person-related expectations in respect of risk consequences, the possibility of personal influencing control, the severeness of risk consequences and one's own risk propensity play a significant role in the evaluation of risks.

  17. The additivity of radionuclide and chemical risk estimates in performance evaluation of mixed-waste sites

    International Nuclear Information System (INIS)

    Till, J.E.; Meyer, K.R.

    1990-01-01

    Methods for assessing radioactive waste sites that contain chemical constituents are in the formative stages. In evaluating these sites, a key concern will be the hazard to personnel involved in cleanup work and to the general population. This paper focuses on what we have learned from pathway analysis and risk assessment about providing a combined estimate of risk from exposure to both chemicals and radionuclides. Quantitative radiation risk assessment involves a high degree of uncertainty. Chemical risk assessment generally does not provide quantitative results. Thus, it is not currently possible to develop a useful, quantitative combined risk assessment for mixed-waste sites

  18. Patient Doses and Risk Evaluation in Bone Mineral Densitometry

    International Nuclear Information System (INIS)

    Angelucci, M.; Borio, R.; Chiocchini, S.; Degli Esposti, P.; Dipilato, A.C.; Policani, G.

    1999-01-01

    The aim of this work was to evaluate the equipment dose to the organs and tissues and the effective dose of patients undergoing the most frequent examinations carried out in bone mineral densitometry (BMD): lumbar spine and femur. Experimental measurements of absorbed doses on a Rando phantom, allow comparison of the performances of three different photon emitter facilities. The comparison of the entrance and exit doses measured on a Rando phantom and on 50 female non-obese patients show that entrance doses on Rando can be used as 'diagnostic reference levels' for patients. A quantitative estimate of the stochastic risk due to BMD procedures was made: the results obtained show that the stochastic risk is very low and that the BMD is, at present, the most confirmed procedure for osteoporosis diagnosis and management. (author)

  19. Evaluation of forest management systems under risk of wildfire

    Science.gov (United States)

    Kari Hyytiainen; Robert G. Haight

    2010-01-01

    We evaluate the economic efficiency of even- and uneven-aged management systems under risk of wildfire. The management problems are formulated for a mixed-conifer stand and approximations of the optimal solutions are obtained using simulation optimization. The Northern Idaho variant of the Forest Vegetation Simulator and its Fire and Fuels Extension is used to predict...

  20. The term 'risk' and its evaluation bases

    International Nuclear Information System (INIS)

    Brueckner, R.

    1976-01-01

    The term risk, the risk itself and its application for radiation exposure in practised medicine is presented from the following points of view: Life expectation, susceptibility to sickness and permanent inability to work, impaired professional and earning capacity, work accident and sickness. (HP) [de

  1. Strengthening air traffic safety management by moving from outcome-based towards risk-based evaluation of runway incursions

    International Nuclear Information System (INIS)

    Stroeve, Sybert H.; Som, Pradip; Doorn, Bas A. van; Bakker, G.J.

    2016-01-01

    Current safety management of aerodrome operations uses judgements of severity categories to evaluate runway incursions. Incident data show a small minority of severe incursions and a large majority of less severe incursions. We show that these severity judgements are mainly based upon the outcomes of runway incursions, in particular on the closest distances attained. As such, the severity-based evaluation leads to coincidental safety management feedback, wherein causes and risk implications of runway incursions are not well considered. In this paper we present a new framework for the evaluation of runway incursions, which effectively uses all runway incursions, which judges same types of causes similarly, and which structures causes and risk implications. The framework is based on risks of scenarios associated with the initiation of runway incursions. As a basis an inventory of scenarios is provided, which can represent almost all runway incursions involving a conflict with an aircraft. A main step in the framework is the assessment of the conditional probability of a collision given a runway incursion scenario. This can be effectively achieved for large sets of scenarios by agent-based dynamic risk modelling. The results provide detailed feedback on risks of runway incursion scenarios, thus enabling effective safety management. - Highlights: • Current evaluation of runway incursions is primarily based on their outcomes. • A new framework assesses collision risk given initiation of runway incursions. • Agent-based dynamic risk modelling can evaluate the risks of many scenarios. • A developed scenario inventory can represent almost all runway incursions. • The framework provides detailed feedback to safety management.

  2. Context-sensitive Information security Risk identification and evaluation techniques

    NARCIS (Netherlands)

    Ionita, Dan

    2014-01-01

    The objective of my research is to improve and support the process of Information security Risk Assessment by designing a scalable Risk argumentation framework for socio-digital-technical Risk. Due to the various types of IT systems, diversity of architectures and dynamic nature of Risk, there is no

  3. Risk allocation approach to reactor safety design and evaluation

    International Nuclear Information System (INIS)

    Gokcek, O.; Temme, M.I.; Derby, S.L.

    1978-01-01

    This paper describes a risk allocation technique used for determining nuclear power plant design reliability requirements. The concept of risk allocation-optimum choice of safety function reliabilities under a maximum risk constraint - is described. An example of risk allocation is presented to demonstrate the application of the methodology

  4. Hanford Site's Integrated Risk Assessment Program: No-intervention risk assessment

    International Nuclear Information System (INIS)

    Mahaffey, J.A.; Dukelow, J.S. Jr.; Stenner, R.D.

    1994-08-01

    The long-term goal of the Integrated Risk Assessment program (IRAP) is to estimate risks to workers, the public, organizations, and groups with reserved rights to Site access, the ecosystem, and natural resources to aid in managing environmental restoration and waste management at the Hanford Site. For each of these, information is needed about current risks, risks during cleanup, and endstate risks. The objective is three-fold: to determine if and when to remediate, and to what extent; to identify information unavailable but needed to make better cleanup decisions; to establish technology performance criteria for achieving desired cleanup levels; to understand costs and benefits of activities from a Site-wide perspective. The no-intervention risk, assessment is the initial evaluation of public health risks conducted under IRAP. The objective is to identify types of activities that the US Department of Energy (DOE) must accomplish for closure of the Hanford Site, defined as no further DOE intervention. There are two primary conclusions from the no-intervention risk assessment. First, some maintenance and operations activities at Hanford must be continued to protect the public from grave risks. However, when large Hanford expenditures are compared to cleanup progress, funds expended for maintenance and operations must be put in proper perspective. Second, stakeholder's emphasis on public risks at Hanford, as indicated by remediation priorities, are not in line with those estimated. The focus currently is on compliance with regulations, and on dealing with issues which are visible to stakeholders

  5. Conventional myelography - evaluation of risk and benefit

    International Nuclear Information System (INIS)

    Hentschel, F.

    1989-01-01

    While the benefit and methodic risk of conventional myelography (KMG) are known, a radiation risk of 0.04 to 0.9 annual radiation-induced cancers can be estimated for all inhabitants of the GDR, dependent on the investigated region and the technique used. An optimized technique can reduce the radiation burden to 50 or 25%. With comparable values of benefit and radiation risk spinal CT and KMG are not contradictory but complementary investigations. Alternative methods (MRT, US) must not be discussed from the standpoint of radiation burden, but according to their availability and their methodic limitations. (author)

  6. Net Reclassification Indices for Evaluating Risk-Prediction Instruments: A Critical Review

    Science.gov (United States)

    Kerr, Kathleen F.; Wang, Zheyu; Janes, Holly; McClelland, Robyn L.; Psaty, Bruce M.; Pepe, Margaret S.

    2014-01-01

    Net reclassification indices have recently become popular statistics for measuring the prediction increment of new biomarkers. We review the various types of net reclassification indices and their correct interpretations. We evaluate the advantages and disadvantages of quantifying the prediction increment with these indices. For pre-defined risk categories, we relate net reclassification indices to existing measures of the prediction increment. We also consider statistical methodology for constructing confidence intervals for net reclassification indices and evaluate the merits of hypothesis testing based on such indices. We recommend that investigators using net reclassification indices should report them separately for events (cases) and nonevents (controls). When there are two risk categories, the components of net reclassification indices are the same as the changes in the true-positive and false-positive rates. We advocate use of true- and false-positive rates and suggest it is more useful for investigators to retain the existing, descriptive terms. When there are three or more risk categories, we recommend against net reclassification indices because they do not adequately account for clinically important differences in shifts among risk categories. The category-free net reclassification index is a new descriptive device designed to avoid pre-defined risk categories. However, it suffers from many of the same problems as other measures such as the area under the receiver operating characteristic curve. In addition, the category-free index can mislead investigators by overstating the incremental value of a biomarker, even in independent validation data. When investigators want to test a null hypothesis of no prediction increment, the well-established tests for coefficients in the regression model are superior to the net reclassification index. If investigators want to use net reclassification indices, confidence intervals should be calculated using bootstrap

  7. Evaluation of a chemical risk assessment method of South Korea for chemicals classified as carcinogenic, mutagenic or reprotoxic (CMR).

    Science.gov (United States)

    Kim, Min-Uk; Byeon, Sang-Hoon

    2017-12-12

    Chemicals were used in various fields by the development of industry and science and technology. The Chemical Hazard Risk Management (CHARM) was developed to assess the risk of chemicals in South Korea. In this study, we were to evaluate the CHARM model developed for the effective management of workplace chemicals. We used 59 carcinogenic, mutagenic or reprotoxic (CMR) materials, which are both the work environment measurement result and the usage information among the manufacturer data. The CHARM model determines the risk to human health using the exposure level (based on working environment measurements or a combination of the quantity used and chemical physical properties (e.g., fugacity and volatility)), hazard (using occupational exposure limit (OEL) or Risk phrases (R-phrases)/Hazard statements (H-statements) from the Material Safety Data Sheet (MSDS)). The risk level was lower when using the results of the work environment measurement than when applying the chemical quantity and physical properties in the exposure level evaluation method. It was evaluated as grade 4 for the CMR material in the hazard class determination. The risk assessment method by R-phrases was evaluated more conservatively than the risk assessment method by OEL. And the risk assessment method by H-statements was evaluated more conservatively than the risk assessment method by R-phrases. The CHARM model was gradually conservatively assessed as it proceeded in the next step without quantitative information for individual workplaces. The CHARM is expected to help identify the risk if the hazards and exposure levels of chemicals were identified in individual workplaces. For CMR substances, although CHARM is highly evaluated for hazards, the risk is assessed to be low if exposure levels are assessed low. When evaluating the risk of highly hazardous chemicals such as CMR substances, we believe the model should be adapted to be more conservative and classify these as higher risk. This work is

  8. Multivariate market risk evaluation between Malaysian Islamic stock index and sectoral indices

    Directory of Open Access Journals (Sweden)

    Sew Lai Ng

    2017-03-01

    Full Text Available Without an efficient financial risk management, it may cause massive consequences to a financial institution as well as individual. Therefore, developing a methodology which gives precise estimates to reduce the exposure of risk to a minimum is of great importance. This paper uses an asymmetric BEKK-GARCH model to examine the return and volatility linkages between the FTSE Bursa Malaysia Emas Shariah (FBMS index and the sectoral indices under a normal market. The findings suggest that the FBMS plays a leading role in the mean return spillover effect. There is a strong evidence of significant transmission of past shocks, volatilities and leverage effects are observed on the current conditional variance-covariance in all the pair-wise models. These empirical results are helpful in quantifying the cross-market risk evaluation, risk minimizing weight and cross-market hedge ratio for strategizing appropriate portfolio selection.

  9. Adolescents' perceived risk and personal experience with natural disasters: an evaluation of cognitive heuristics.

    Science.gov (United States)

    Greening, L; Dollinger, S J; Pitz, G

    1996-02-01

    Elevated risk judgments for negative life events have been linked to personal experience with events. We tested the hypothesis that cognitive heuristics are the underlying cognitive mechanism for this relation. The availability (i.e., memory for incidents) and simulation (i.e., imagery) heuristics were evaluated as possible mediators for the relation between personal experience and risk estimates for fatal weather events. Adolescents who had experienced weather disasters estimated their personal risk for weather events. Support was obtained for the simulation heuristic (imagery) as a mediator for the relation. Availability for lightning disaster experience was also found to be a mediator for the relation between personal lightning disaster experience and risk estimate for future events. The implications for risk perception research are discussed.

  10. A Taxonomy of Operational Risks

    National Research Council Canada - National Science Library

    Gallagher, Brian P; Case, Pamela J; Creel, Rita C; Kushner, Susan; Williams, Ray C

    2005-01-01

    ... identification of risks associated with the development of a software-dependent project. Since then, this method also has been used in the Software Risk Evaluation process to identify risks associated with the development of software-intensive systems...

  11. Radiation and risk

    International Nuclear Information System (INIS)

    Jacobi, W.

    1983-01-01

    From the beginnings of the peaceful utilization of nuclear energy, the principles of prevention and optimization have greatly limited the emission of radioactive substances. In this way, the radiation exposure associated with emissions from nuclear power plants during normal operation has been kept low compared with natural radiation exposure and its variance. This also applies to the local public in the vicinities of such plants. The present health hazard to the public arising from ionizing radiation is only a small fraction of the man-made risk to which the public is exposed in this country. This is also due to the fact that radiation protection employs the principle of prevention, which has been laid down in legal regulations. In this respect, the concepts and criteria developed in radiation protection for evaluation, limitation and optimization may be useful examples to other areas of safety at work and environmental protection. The acceptance of nuclear power is decisively influenced by the remaining residual risk of accidents. Extremely careful inspection and supervision of the technical safety of such plants is indispensable to prevent major accidents. The German Risk Study for Nuclear Power Plants has made an important contribution to this end. It is being continued. However, risk research must always be accompanied by risk comparison to allow numerical risk data to be evaluated properly and important features to be distinguished from unimportant ones. (orig.) [de

  12. Evaluation of risk management status for Croatian logistic operators

    Directory of Open Access Journals (Sweden)

    Diana BOŽIĆ

    2010-01-01

    Full Text Available Understanding organisational risks makes possible to control them and to change them into organisational strengths. Being known as “measure of uncertainty” in the business process, the risk is the uncertainty of achieving the organizational objectives. It may involve positive or negative consequences. There is a level of uncertainty in every supply chain while operating transportation and warehousing, positioning on the market, developing customer support, reducing cycle times or cutting costs. Therefore, the risk assessment should be one of the main tasks for any supply chain management team. It is required to develop formal risk assessment procedures, to identify the potential impacts to the supply chain operations and to develop a set of contingency plans to mitigate risks. This paper deals with supply chain risk assessment methodology, outlining the present risk management status of Croatian logistic operators.

  13. Evaluating the Investment Benefit of Multinational Enterprises' International Projects Based on Risk Adjustment: Evidence from China

    Science.gov (United States)

    Chen, Chong

    2016-01-01

    This study examines the international risks faced by multinational enterprises to understand their impact on the evaluation of investment projects. Moreover, it establishes a 'three-dimensional' theoretical framework of risk identification to analyse the composition of international risk indicators of multinational enterprises based on the theory…

  14. A risk communication case study: the Nevada risk assessment/management program

    International Nuclear Information System (INIS)

    Hechanova, A.E.

    2000-01-01

    The Nevada Risk Assessment/Management Program (NRAMP) is part of a national effort by the U.S. Department of Energy (DOE) to develop new sources of information and approaches to risk assessment, risk management, risk communication and public outreach as these objectives relate to the ecological and human health effects of radioactive and hazardous material management and site remediation activities. This paper reviews the innovation behind the NRAMP project and presents a synopsis of the NRAMP effort which occurred from 1995 to 2000. The primary goals of the DOE in awarding the cooperative agreement establishing NRAMP were to (I) use a risk-based approach to evaluate the consequences of alternative actions in DOE's Environmental Remediation Programs at sites in Nevada and (2) use a neutral and credible institution outside the DOE to perform the risk assessments and contribute to public education about environmental management issues at the Nevada Test Site. (author)

  15. A risk assessment methodology to evaluate the risk failure of managed aquifer recharge in the Mediterranean Basin

    Science.gov (United States)

    Rodríguez-Escales, Paula; Canelles, Arnau; Sanchez-Vila, Xavier; Folch, Albert; Kurtzman, Daniel; Rossetto, Rudy; Fernández-Escalante, Enrique; Lobo-Ferreira, João-Paulo; Sapiano, Manuel; San-Sebastián, Jon; Schüth, Christoph

    2018-06-01

    Managed aquifer recharge (MAR) can be affected by many risks. Those risks are related to different technical and non-technical aspects of recharge, like water availability, water quality, legislation, social issues, etc. Many other works have acknowledged risks of this nature theoretically; however, their quantification and definition has not been developed. In this study, the risk definition and quantification has been performed by means of fault trees and probabilistic risk assessment (PRA). We defined a fault tree with 65 basic events applicable to the operation phase. After that, we have applied this methodology to six different managed aquifer recharge sites located in the Mediterranean Basin (Portugal, Spain, Italy, Malta, and Israel). The probabilities of the basic events were defined by expert criteria, based on the knowledge of the different managers of the facilities. From that, we conclude that in all sites, the perception of the expert criteria of the non-technical aspects were as much or even more important than the technical aspects. Regarding the risk results, we observe that the total risk in three of the six sites was equal to or above 0.90. That would mean that the MAR facilities have a risk of failure equal to or higher than 90 % in the period of 2-6 years. The other three sites presented lower risks (75, 29, and 18 % for Malta, Menashe, and Serchio, respectively).

  16. Risk-benefit evaluation of nuclear power plant siting

    International Nuclear Information System (INIS)

    Miettinen, J.; Savolainen, I.; Silvennoinen, P.

    1976-01-01

    An assessment scheme is described for the risk-benefit analyses of nuclear power versus conventional alternatives. Given the siting parameters for the proposed nuclear plant an economic comparison is made with the most advantageous competitive conventional production scenario. The economic benefit is determined from the differential discounted annual energy procurement cost as a function of the real interest rate and amortization time. The risk analysis encompasses the following factors: radiation risks in normal operation, reactor accident hazards and economic risks, atmospheric pollutants from the conventional power plants, and fuel transportation. The hazards are first considered in terms of probabilistic dose distributions. In the second stage risk components are converted to a compatible form where excess mortality is used as the risk indicator. Practical calculations are performed for the power production alternatives of Helsinki where district heat would be extracted from the nuclear power plant. At the real interest rate of 10% and amortization time of 20 yr the 1000 MW(e) nuclear option is found to be Pound9.1 m per yr more economic than the optimal conventional scenario. Simultaneously the nuclear alternative is estimated to reduce excess mortality by 2 to 5 fatal injuries annually. (author)

  17. Actuarial Evaluation of Pension Risks of Russia: from Theory to Practice

    Directory of Open Access Journals (Sweden)

    Aleksandr Anatolyevich Kuklin

    2017-09-01

    Full Text Available The article discusses the origins of the development of pension systems in the world, shows the causes of the emergence of various models of public pension provision. We pay a particular attention to the history of the formation of the Russian pension system, and analyse the stages and causes of modern reform. From the position of modern legislation, we systemise the forms, types of pension provision and pension insurance in the Russian Federation from the point of view of the sources of financing and subjects of pension relations. The authors have defined the concept of “actuarial evaluation” from the point of view of the process and system approach. We have revealed the content of the pension risk category, as well as classified the pension risks by the spheres of origin. The authors have developed the methodology of actuarial estimation of the risks of the pension system classified by different criteria: demographic, economic, financial, labor risks. The proposed methodological approach to the evaluation of pension risks is based on the comprehensive assessment of socio-economic indicators and the identification of dependencies between socio-demographic and economic processes in the pension system and economy of the country. The authors have tested the developed tools on the actuarial estimation of the pension risks of the Russian Federation. The article presents the results of calculations and identifies critical risks for the Russian pension system. We have proved that stagnation processes in the economy and a high share of the shadow economy represent the greatest threat to the Russian pension system in the short term, whereas, the aging of the population and the increase in life expectancy — in the long term.

  18. The third experiment of operation and evaluation of online risk communication assistant tool, 'ORCAT'

    International Nuclear Information System (INIS)

    Katsumura, Soichiro; Kimura, Hiroshi; Furuta, Kazuo; Tanaka, Hiroshi

    2006-01-01

    Risk communication about the high-level radioactive waste (HLW) disposal is necessary for public acceptance of HLW disposal program. Online Risk Communication Assistant Tool (ORCAT) system is developed in order to support risk communication for HLW disposal on World Wide Web. We have been evaluating ORCAT system. After two test operations, we carried out the third test operation from Aug. 29 to Dec. 12, 2005. In the third test operation, 100 participants answered the questionnaires about the attitude change and knowledge. We classified the participants into two groups by the analysis on the number of login a week, and analyzed the change of the amount of subjective and objective knowledge. In the result of analysis on knowledge, the increase of amount of subjective knowledge doesn't always carried the increase of amount of objective knowledge. On the whole we found that the ORCAT system is evaluated useful to the risk communication about the HLW disposal. (author)

  19. Absolute risk, absolute risk reduction and relative risk

    Directory of Open Access Journals (Sweden)

    Jose Andres Calvache

    2012-12-01

    Full Text Available This article illustrates the epidemiological concepts of absolute risk, absolute risk reduction and relative risk through a clinical example. In addition, it emphasizes the usefulness of these concepts in clinical practice, clinical research and health decision-making process.

  20. The risks of technology

    International Nuclear Information System (INIS)

    Hauptmanns, U.; Werner, W.; Herttrich, M.

    1987-01-01

    The book presents a complete survey of the methods and procedures applied for risk assessment, referring in particular to the field of nuclear engineering, but dealing also with risk assessment in the sector of the chemical industry and of the power industry, comparing the risks of various technologies for energy production. The material presented shows that a risk assessment study requires information and knowledge from a great variety of subject fields, evaluating and merging the information collected into a complete survey being the main task of risk assessment. It also becomes clear that despite the strong commitment to research in this field, there still remain unresolved problems and phenomena, so that risk assessment bears a certain degree of uncertainty. The results and the mutual connections are represented in words only, so that the reader can do without mathematical knowledge. Many studies and their results are presented, and their explanation in the overall framework allows insight into the connections and an evaluation of usefulness. The status report on risk assessment prepared in August 1984 by the GRS (Society for Reactor Safety) on behalf of the Federal Ministry of the Interior, has been taken as a basis for this book which consists of many individual contributions. (orig./HP) With 45 figs [de

  1. Evaluation of knowledge loss risk in nuclear industry and research organizations

    International Nuclear Information System (INIS)

    Constantin, Marin; Apostol, Minodora; Balaceanu, Victoria

    2007-01-01

    Institutional knowledge is defined as a collective knowledge of all employees in an organization or institution. The necessity to maintain organizational competency for nuclear power has been widely recognized given the nature of the business and the life cycle of 100 years or more. Our paper is intended to perform the first step in the knowledge loss risk assessment in nuclear organizations in Romania. Generally a three step procedure is needed for the evaluation process: - conducting the knowledge loss risk assessment; - determination of the approach needed to capture critical knowledge; - monitoring and evaluation. Taking into account the specificity of problems at organizational/institutional level, the difficulty of finding of a common approach, and the necessity to harmonize different interests at national level, a National Nuclear Knowledge Strategy is compulsory needed. (authors)

  2. Safety evaluations by means of the method use of the risk matrix in radiotherapy treatments

    International Nuclear Information System (INIS)

    Sanchez, L.; Diaz, A.; Correa, T.; Gonzalez, Y.

    2014-08-01

    The quality of a radiotherapy treatment is linked to multidisciplinary factors that need to be taken into account in combined form whenever an evaluation of the safety is carried out. Knowing the accidents happened in this area, and to guarantee their prevention, the causes and sequences that could behave to them should be controlled, for what is necessary to make periodic evaluations of the same one. Our objective was to carry out the safety evaluation to the treatment process of a radiotherapy service and to identify the causes and consequences that can cause these accidental exposures, for patients, worker or people, from the equipment installation until the treatment completion. The method of Risk Matrices was used, by means the SEVRRA system carried out by the Comision Nacional de Seguridad Nuclear y Salvaguardias of Mexico; this system allows to carry out a combined analysis of the occurrence frequency of the event initiator, the probability of human errors or barrier failures and the graveness of the consequences, facilitating the identification of the associated risk to the radiotherapy procedures. The method establishes priorities for the risk administration and identifies the main causes that could cause accidental exposures; also allows preventing the accidents occurrence using risk criterions that take into account the probability and magnitude of the potential exposures. This method, although does not allow to quantify numerically the risk, makes possible to classify it in levels, what is enough to establish priorities, without carrying out risks analysis but precise but more expensive. As a result we obtained that for the Co 60 77% of the treatments, is realized with low or half risk and 23% with high risk; the work load that is elevated in our case, intervenes directly in 46 initiators, in second and third place, the non realization of a portal image in the first treatment section and in the weekly continuation, as a consequences reducer, but these

  3. Evaluation of radiation risk and work practices during cerebral interventions

    Energy Technology Data Exchange (ETDEWEB)

    Livingstone, Roshan S; Raghuram, L; Korah, Ipeson P; Raj, D Victor [Department of Radiodiagnosis, Christian Medical College, Vellore 632004 (India)

    2003-09-01

    This study was intended to evaluate radiation risk to patients during cerebral interventions and the contribution to this risk from work practices. Thirty nine patients undergoing cerebral interventions in a digital subtraction angiography suite were included in this study. Patients who underwent cerebral interventions were categorised into two groups according to the number of cerebral interventions performed on them, and their effective doses were calculated. The effective dose for patients undergoing a single cerebral intervention (group A) varied from 1.55 to 15.9 mSv and for multiple cerebral interventions (group B) varied from 16.52 to 43.52 mSv. Two patients who underwent multiple cerebral interventions (group B) had alopecia of the irradiated scalp.

  4. A quantitative risk assessment model to evaluate effective border control measures for rabies prevention

    Science.gov (United States)

    Weng, Hsin-Yi; Wu, Pei-I; Yang, Ping-Cheng; Tsai, Yi-Lun; Chang, Chao-Chin

    2009-01-01

    Border control is the primary method to prevent rabies emergence. This study developed a quantitative risk model incorporating stochastic processes to evaluate whether border control measures could efficiently prevent rabies introduction through importation of cats and dogs using Taiwan as an example. Both legal importation and illegal smuggling were investigated. The impacts of reduced quarantine and/or waiting period on the risk of rabies introduction were also evaluated. The results showed that Taiwan’s current animal importation policy could effectively prevent rabies introduction through legal importation of cats and dogs. The median risk of a rabid animal to penetrate current border control measures and enter Taiwan was 5.33 × 10−8 (95th percentile: 3.20 × 10−7). However, illegal smuggling may pose Taiwan to the great risk of rabies emergence. Reduction of quarantine and/or waiting period would affect the risk differently, depending on the applied assumptions, such as increased vaccination coverage, enforced custom checking, and/or change in number of legal importations. Although the changes in the estimated risk under the assumed alternatives were not substantial except for completely abolishing quarantine, the consequences of rabies introduction may yet be considered to be significant in a rabies-free area. Therefore, a comprehensive benefit-cost analysis needs to be conducted before recommending these alternative measures. PMID:19822125

  5. Conscious worst case definition for risk assessment, part I: a knowledge mapping approach for defining most critical risk factors in integrative risk management of chemicals and nanomaterials.

    Science.gov (United States)

    Sørensen, Peter B; Thomsen, Marianne; Assmuth, Timo; Grieger, Khara D; Baun, Anders

    2010-08-15

    This paper helps bridge the gap between scientists and other stakeholders in the areas of human and environmental risk management of chemicals and engineered nanomaterials. This connection is needed due to the evolution of stakeholder awareness and scientific progress related to human and environmental health which involves complex methodological demands on risk management. At the same time, the available scientific knowledge is also becoming more scattered across multiple scientific disciplines. Hence, the understanding of potentially risky situations is increasingly multifaceted, which again challenges risk assessors in terms of giving the 'right' relative priority to the multitude of contributing risk factors. A critical issue is therefore to develop procedures that can identify and evaluate worst case risk conditions which may be input to risk level predictions. Therefore, this paper suggests a conceptual modelling procedure that is able to define appropriate worst case conditions in complex risk management. The result of the analysis is an assembly of system models, denoted the Worst Case Definition (WCD) model, to set up and evaluate the conditions of multi-dimensional risk identification and risk quantification. The model can help optimize risk assessment planning by initial screening level analyses and guiding quantitative assessment in relation to knowledge needs for better decision support concerning environmental and human health protection or risk reduction. The WCD model facilitates the evaluation of fundamental uncertainty using knowledge mapping principles and techniques in a way that can improve a complete uncertainty analysis. Ultimately, the WCD is applicable for describing risk contributing factors in relation to many different types of risk management problems since it transparently and effectively handles assumptions and definitions and allows the integration of different forms of knowledge, thereby supporting the inclusion of multifaceted risk

  6. JCL roundtable: Risk evaluation and mitigation strategy.

    Science.gov (United States)

    Brown, W Virgil; Bramlet, Dean A; Ross, Joyce L; Underberg, James A

    Many factors enter into the decision by the Food and Drug Administration (FDA) to approve a new drug for use by physicians and other health care providers in treating diseases. Initially, the FDA authority was restricted to issues of safety and only later did the documentation of efficacy become part of the review process required for approval. However, all drugs have the potential for causing harm at some dose level to all and at lower doses in certain patients with vulnerability to the particular pharmacology of the agent. As new drugs have been designed to manage disorders that are uncommon, but of significant consequence, they may have adverse effects that are acceptable only because they are so uniquely beneficial to these specific conditions. The risk of these adverse effects may be acceptable since the benefit can outweigh the harm in most patients and the adversity can be predicted and managed. The approval of this category of drugs has grown rapidly since definition of a mechanism of action to manage and modify the risk has been provided by a process known as known as Risk Evaluation and Mitigation Strategy or "REMS." In 2007, the Food and Drug Administration Amendments Act (FDAAA) allowed the FDA to require postmarketing studies and the authority to mandate the implementation of a REMS for drugs with efficacy but documented potential for harm. Two relatively new drugs useful in the management of severe elevations of low-density lipoprotein cholesterol have been approved under a requirement for a REMS. These are lomitapide, an inhibitor of microsomal triglyceride transfer protein and mipomersen, an antisense oligonucleotide which reduces the synthesis of apolipoprotein B. Copyright © 2016 National Lipid Association. Published by Elsevier Inc. All rights reserved.

  7. LOW DOSE RISK, DECISIONS, and RISK COMMUNICATION

    International Nuclear Information System (INIS)

    Flynn, James

    2002-01-01

    The objective of this project is to conduct basic research on how people receive, evaluate, and form positions on scientific information and its relationship to low-dose radiation exposure. There are three major areas of study in our research program. First is the development of theories, frameworks and concepts essential to guiding data collection and analysis. The second area is a program of experimental studies on risk perception, evaluation of science information, and the structure of individual positions regarding low-dose exposures. Third is the community-level studies to examine and record how the social conditions, under which science communications take place, influence the development of attitudes and opinions about: low-dose exposures, the available management options, control of radiation risks, and preferences for program and policy goals

  8. Evaluating the operational risks of biomedical waste using failure mode and effects analysis.

    Science.gov (United States)

    Chen, Ying-Chu; Tsai, Pei-Yi

    2017-06-01

    The potential problems and risks of biomedical waste generation have become increasingly apparent in recent years. This study applied a failure mode and effects analysis to evaluate the operational problems and risks of biomedical waste. The microbiological contamination of biomedical waste seldom receives the attention of researchers. In this study, the biomedical waste lifecycle was divided into seven processes: Production, classification, packaging, sterilisation, weighing, storage, and transportation. Twenty main failure modes were identified in these phases and risks were assessed based on their risk priority numbers. The failure modes in the production phase accounted for the highest proportion of the risk priority number score (27.7%). In the packaging phase, the failure mode 'sharp articles not placed in solid containers' had the highest risk priority number score, mainly owing to its high severity rating. The sterilisation process is the main difference in the treatment of infectious and non-infectious biomedical waste. The failure modes in the sterilisation phase were mainly owing to human factors (mostly related to operators). This study increases the understanding of the potential problems and risks associated with biomedical waste, thereby increasing awareness of how to improve the management of biomedical waste to better protect workers, the public, and the environment.

  9. Evaluation of sustainable supply chain risk management using an integrated fuzzy TOPSIS- CRITIC approach

    DEFF Research Database (Denmark)

    Rostamzadeh, Reza; Ghorabaee, Mehdi Keshavarz; Govindan, Kannan

    2018-01-01

    Supply chain risk management research has mainly mistreated the important of sustainability issues. Moreover, there is little knowledge about sustainable management of risk and supply chain and the way they impose losses for firms. Risk management's duty in the supply chain is to identify, analyze......, and provide solutions for accountability, control and monitor the risks in the economic and production cycle. This study aims to develop a framework for the sustainable supply chain risk management (SSCRM) evaluation. To this end, an integrated fuzzy multi-criteria decision-making (MCDM) approach is proposed...... based on the technique in order of preference by similarity to ideal solution (TOPSIS) and criteria importance through inter-criteria correlation (CRITIC) methods. The literature was reviewed and the potential criteria were identified. Through an expert panel the criteria were filtered. Seven main...

  10. Nanoparticle risk management and cost evaluation: a general framework

    Science.gov (United States)

    Fleury, Dominique; Bomfim, João A. S.; Metz, Sébastien; Bouillard, Jacques X.; Brignon, Jean-Marc

    2011-07-01

    Industrial production of nano-objects has been growing fast during the last decade and a wide range of products containing nanoparticles (NPs) is proposed to the public in various markets (automotive, electronics, textiles...). The issues encountered in monitoring the presence of nano-objects in any media cause a major difficulty for controlling the risk associated to the production stage. It is therefore very difficult to assess the efficiency of prevention and mitigation solutions, which potentially leads to overestimate the level of the protection barriers that are recommended. The extra costs in adding nano-objects to the process, especially that of nanosafety, must be estimated and optimized to ensure the competitiveness of the future production lines and associated products. The risk management and cost evaluation methods presented herein have been designed for application in a pilot production line of injection-moulded nanocomposites.

  11. Nanoparticle risk management and cost evaluation: a general framework

    International Nuclear Information System (INIS)

    Fleury, Dominique; Metz, Sebastien; Bouillard, Jacques X; Brignon, Jean-Marc; Bomfim, Joao A S

    2011-01-01

    Industrial production of nano-objects has been growing fast during the last decade and a wide range of products containing nanoparticles (NPs) is proposed to the public in various markets (automotive, electronics, textiles...). The issues encountered in monitoring the presence of nano-objects in any media cause a major difficulty for controlling the risk associated to the production stage. It is therefore very difficult to assess the efficiency of prevention and mitigation solutions, which potentially leads to overestimate the level of the protection barriers that are recommended. The extra costs in adding nano-objects to the process, especially that of nanosafety, must be estimated and optimized to ensure the competitiveness of the future production lines and associated products. The risk management and cost evaluation methods presented herein have been designed for application in a pilot production line of injection-moulded nanocomposites.

  12. How Fear-Arousing News Messages Affect Risk Perceptions and Intention to Talk About Risk.

    Science.gov (United States)

    Paek, Hye-Jin; Oh, Sang-Hwa; Hove, Thomas

    2016-09-01

    Building on the theoretical arguments of the impersonal-impact and differential-impact hypotheses, this study has a twofold purpose: first, to demonstrate how fear-arousing media messages about risk are associated with personal-level risk perception, as well as, and perhaps more so than, societal-level risk perception; and second, to examine how the resulting risk perceptions can mediate intention to talk about the risk with family and friends. A news message evaluation study was conducted among the general public in South Korea concerning two major risks, carcinogens and bovine spongiform encephalopathy (BSE). Two sets of structural equation models reveal three main findings: (a) Fear-arousing news messages are positively related to personal-level risk perception, as well as to societal-level risk perception; (b) fear-arousing news messages result in intention to talk about the risk directly and indirectly through risk perception; and (c) personal-level risk perception appears more strongly related to intention to talk than does societal-level risk perception, although such relationships may vary across risk topics.

  13. Quantified Risk Ranking Model for Condition-Based Risk and Reliability Centered Maintenance

    Science.gov (United States)

    Chattopadhyaya, Pradip Kumar; Basu, Sushil Kumar; Majumdar, Manik Chandra

    2017-06-01

    In the recent past, risk and reliability centered maintenance (RRCM) framework is introduced with a shift in the methodological focus from reliability and probabilities (expected values) to reliability, uncertainty and risk. In this paper authors explain a novel methodology for risk quantification and ranking the critical items for prioritizing the maintenance actions on the basis of condition-based risk and reliability centered maintenance (CBRRCM). The critical items are identified through criticality analysis of RPN values of items of a system and the maintenance significant precipitating factors (MSPF) of items are evaluated. The criticality of risk is assessed using three risk coefficients. The likelihood risk coefficient treats the probability as a fuzzy number. The abstract risk coefficient deduces risk influenced by uncertainty, sensitivity besides other factors. The third risk coefficient is called hazardous risk coefficient, which is due to anticipated hazards which may occur in the future and the risk is deduced from criteria of consequences on safety, environment, maintenance and economic risks with corresponding cost for consequences. The characteristic values of all the three risk coefficients are obtained with a particular test. With few more tests on the system, the values may change significantly within controlling range of each coefficient, hence `random number simulation' is resorted to obtain one distinctive value for each coefficient. The risk coefficients are statistically added to obtain final risk coefficient of each critical item and then the final rankings of critical items are estimated. The prioritization in ranking of critical items using the developed mathematical model for risk assessment shall be useful in optimization of financial losses and timing of maintenance actions.

  14. Taking the Risk Out of Risk Assessment

    Science.gov (United States)

    2005-01-01

    The ability to understand risks and have the right strategies in place when risky events occur is essential in the workplace. More and more organizations are being confronted with concerns over how to measure their risks or what kind of risks they can take when certain events transpire that could have a negative impact. NASA is one organization that faces these challenges on a daily basis, as effective risk management is critical to the success of its missions especially the Space Shuttle missions. On July 29, 1996, former NASA Administrator Daniel Goldin charged NASA s Office of Safety and Mission Assurance with developing a probabilistic risk assessment (PRA) tool to support decisions on the funding of Space Shuttle upgrades. When issuing the directive, Goldin said, "Since I came to NASA [in 1992], we've spent billions of dollars on Shuttle upgrades without knowing how much they improve safety. I want a tool to help base upgrade decisions on risk." Work on the PRA tool began immediately. The resulting prototype, the Quantitative Risk Assessment System (QRAS) Version 1.0, was jointly developed by NASA s Marshall Space Flight Center, its Office of Safety and Mission Assurance, and researchers at the University of Maryland. QRAS software automatically expands the reliability logic models of systems to evaluate the probability of highly detrimental outcomes occurring in complex systems that are subject to potential accident scenarios. Even in its earliest forms, QRAS was used to begin PRA modeling of the Space Shuttle. In parallel, the development of QRAS continued, with the goal of making it a world-class tool, one that was especially suited to NASA s unique needs. From the beginning, an important conceptual goal in the development of QRAS was for it to help bridge the gap between the professional risk analyst and the design engineer. In the past, only the professional risk analyst could perform, modify, use, and perhaps even adequately understand PRA. NASA wanted

  15. Risk Factor Assessment Branch (RFAB)

    Science.gov (United States)

    The Risk Factor Assessment Branch (RFAB) focuses on the development, evaluation, and dissemination of high-quality risk factor metrics, methods, tools, technologies, and resources for use across the cancer research continuum, and the assessment of cancer-related risk factors in the population.

  16. A risk-informed evaluation of MOX fuel loading in PWRS

    International Nuclear Information System (INIS)

    Lyman, E.S.

    2001-01-01

    The full text follows: The U.S. Department of Energy (DOE) has signed a contract with Duke Cogema Stone and Webster (DCS) for fabrication of mixed-oxide (MOX) fuel and irradiation of the MOX fuel at the Catawba and McGuire pressurized-water reactors (PWRs), operated by Duke Power. The first load of MOX fuel is scheduled for 2007. In order to use MOX in these plants, Duke Power will have to apply to the Nuclear Regulatory Commission (NRC) for amendments to their operating licenses. Until recently, there have been no numerical guidelines for determining the acceptability of license amendment requests. However, such guidelines are now at hand with the adoption in 1998 of NRC Regulatory Guide 1.174, which defines a maximum value for the permissible increase in risk to the public resulting from a proposed change to a nuclear plant's licensing basis (LB). The substitution of MOX fuel for low-enriched uranium (LEU) fuel in LWRs will have an impact on risk to the public that will require regulatory evaluation. One of the major differences is that use of MOX will increase the inventories of plutonium and minor actinides in the reactor core, thereby increasing the source term for certain severe accidents, such as a core melt with early containment failure or a spent fuel pool drain-down. The goal of this paper is to quantitatively evaluate the increase in risk associated with the greater actinide source term in MOX-fueled reactors, and to compare this increase with RG 1.174 guidelines. Standard computer programs (SCALE and MACCS2) are used to estimate the increase in severe accident risk to the public associated with the DCS plan to use 40% cores of weapons-grade MOX fuel. These values are then compared to the RG 1.174 acceptance criteria, using publicly available risk information. Since RG 1.174 guidelines are based on the assumption that severe accident source terms are not affected by LB changes, the RG 1.174 formalism must be modified for this case. A similar

  17. ATWS: a reappraisal, part II, evaluation of societal risks due to reactor protection systems failure. Vol. 3. Pwr risk analysis. Phase report

    International Nuclear Information System (INIS)

    Lellouche, G.S.

    1976-08-01

    This document is the third volume of part 2 in a series of studies which will examine the basis for the problem of Anticipated Transients Without Scram (ATWS). The purpose of part 2 is an evaluation of societal risks due to RPS failure based on more current data and methodology than used in WASH-1270. This volume examines and documents the potential contribution to societal risk due to ATWS in the PWR. Volumes 1 and 2 described a similar analysis for the BWR

  18. Low-Dose Risk, Decisions, and Risk Communication

    International Nuclear Information System (INIS)

    Flynn, James; Slovic, Paul

    2001-01-01

    To conduct basic research on how people receive, evaluate, and form positions on scientific information and its relationship to low-dose radiation exposure. There are three major areas of study in our research program. First is the development of theories, frameworks and concepts essential to guiding data collection and analysis. The second area is a program of experimental studies on risk perception, evaluation of science information, and the structure of individual positions regarding low dose exposures. This involves the study of existing knowledge and the evaluation of science information presented within a variety of formats, as educational information, news media stories, and alternative communication methods (personal contact, small group interaction, email and internet, etc.). Third is the community-level studies to examine and record how the social conditions, under which science communications take place, influence the development of attitudes and opinions about: low- dose exposures, the available management options, control of radiation risks, and preferences for program and policy goals

  19. Nonparametric evaluation of dynamic disease risk: a spatio-temporal kernel approach.

    Directory of Open Access Journals (Sweden)

    Zhijie Zhang

    Full Text Available Quantifying the distributions of disease risk in space and time jointly is a key element for understanding spatio-temporal phenomena while also having the potential to enhance our understanding of epidemiologic trajectories. However, most studies to date have neglected time dimension and focus instead on the "average" spatial pattern of disease risk, thereby masking time trajectories of disease risk. In this study we propose a new idea titled "spatio-temporal kernel density estimation (stKDE" that employs hybrid kernel (i.e., weight functions to evaluate the spatio-temporal disease risks. This approach not only can make full use of sample data but also "borrows" information in a particular manner from neighboring points both in space and time via appropriate choice of kernel functions. Monte Carlo simulations show that the proposed method performs substantially better than the traditional (i.e., frequency-based kernel density estimation (trKDE which has been used in applied settings while two illustrative examples demonstrate that the proposed approach can yield superior results compared to the popular trKDE approach. In addition, there exist various possibilities for improving and extending this method.

  20. Evaluation of dysphagia risk, nutritional status and caloric intake in elderly patients with Alzheimer's

    Science.gov (United States)

    Goes, Vanessa Fernanda; Mello-Carpes, Pâmela Billig; de Oliveira, Lilian Oliveira; Hack, Jaqueline; Magro, Marcela; Bonini, Juliana Sartori

    2014-01-01

    Objective to evaluate the risk of dysphagia and its relationship with the stage of Alzheimer's Disease, as well as the relationship between the risk of dysphagia and nutritional status and caloric intake in elderly people with Alzheimer's disease. Methods the sample consisted of 30 subjects of both genders with probable Alzheimer's disease. The stage of the disease, nutritional status, energy intake, and risk of dysphagia were assessed. Results it was found that increased risk of dysphagia is associated with the advance in the stages of Alzheimer's disease and that even patients in the early stages of disease have a slight risk of developing dysphagia. No association was found between nutritional status and the risk of dysphagia. High levels of inadequate intake of micronutrients were also verified in the patients. Conclusion an association between dysphagia and the development of Alzheimer's disease was found. The results indicate the need to monitor the presence of dysphagia and the micronutrient intake in patients with Alzheimer's disease. PMID:26107841

  1. Evaluation of dysphagia risk, nutritional status and caloric intake in elderly patients with Alzheimer's

    Directory of Open Access Journals (Sweden)

    Vanessa Fernanda Goes

    2014-04-01

    Full Text Available OBJECTIVE: to evaluate the risk of dysphagia and its relationship with the stage of Alzheimer's Disease, as well as the relationship between the risk of dysphagia and nutritional status and caloric intake in elderly people with Alzheimer's disease.METHODS: the sample consisted of 30 subjects of both genders with probable Alzheimer's disease. The stage of the disease, nutritional status, energy intake, and risk of dysphagia were assessed.RESULTS: it was found that increased risk of dysphagia is associated with the advance in the stages of Alzheimer's disease and that even patients in the early stages of disease have a slight risk of developing dysphagia. No association was found between nutritional status and the risk of dysphagia. High levels of inadequate intake of micronutrients were also verified in the patients.CONCLUSION: an association between dysphagia and the development of Alzheimer's disease was found. The results indicate the need to monitor the presence of dysphagia and the micronutrient intake in patients with Alzheimer's disease.

  2. Risk Factors for Upper and Lower Urinary Tract Cancer Death in a Japanese Population: Findings from the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study).

    Science.gov (United States)

    Washio, Masakazu; Mori, Mitsuru; Mikami, Kazuya; Miki, Tsuneharu; Watanabe, Yoshiyuki; Nakao, Masahiro; Kubo, Tatsuhiko; Suzuki, Koji; Ozasa, Kotaro; Wakai, Kenji; Tamakoshi, Akiko

    2016-01-01

    The incidence of bladder cancer is lower in Asian than in Western countries. However, the crude incidence and mortality of bladder cancer have recently increased in Japan because of the increased number of senior citizens. We have already reported risk factors for urothelial cancer in a large populationbased cohort study in Japan (JACC study). However, we did not evaluate the cancer risk in the upper and lower urinary tract separately in our previous study. Here we evaluated the risk of cancer death in the upper and lower urinary tracts, separately, using the database of the JACC study. The analytic cohort included 46,395 males and 64,190 females aged 40 to 79 years old. The Cox proportional hazard model was used to determine hazard ratios and their 95% confidence intervals. Current smoking increased the risk of both upper and lower urinary tract cancer deaths. A history of kidney disease was associated with an increased risk of bladder cancer death, even after controlling for age, sex and smoking status. The present study confirmed that current smoking increases the risk of both upper and lower urinary tract cancer deaths and indicated the possibility that a history of kidney disease may be a risk factor for bladder cancer death in the Japanese population.

  3. Evaluating Portfolio Value-At-Risk Using Semi-Parametric GARCH Models

    NARCIS (Netherlands)

    J.V.K. Rombouts; M.J.C.M. Verbeek (Marno)

    2009-01-01

    textabstractIn this paper we examine the usefulness of multivariate semi-parametric GARCH models for evaluating the Value-at-Risk (VaR) of a portfolio with arbitrary weights. We specify and estimate several alternative multivariate GARCH models for daily returns on the S&P 500 and Nasdaq indexes.

  4. Risk Stratification for Athletes and Adventurers in High-Altitude Environments: Recommendations for Preparticipation Evaluation.

    Science.gov (United States)

    Campbell, Aaron D; McIntosh, Scott E; Nyberg, Andy; Powell, Amy P; Schoene, Robert B; Hackett, Peter

    2015-12-01

    High-altitude athletes and adventurers face a number of environmental and medical risks. Clinicians often advise participants or guiding agencies before or during these experiences. Preparticipation evaluation (PPE) has the potential to reduce risk of high-altitude illnesses in athletes and adventurers. Specific conditions susceptible to high-altitude exacerbation also important to evaluate include cardiovascular and lung diseases. Recommendations by which to counsel individuals before participation in altitude sports and adventures are few and of limited focus. We reviewed the literature, collected expert opinion, and augmented principles of a traditional sport PPE to accommodate the high-altitude wilderness athlete/adventurer. We present our findings with specific recommendations on risk stratification during a PPE for the high-altitude athlete/adventurer. Copyright © 2015. Published by Elsevier Inc.

  5. Characterizing uncertainty when evaluating risk management metrics: risk assessment modeling of Listeria monocytogenes contamination in ready-to-eat deli meats.

    Science.gov (United States)

    Gallagher, Daniel; Ebel, Eric D; Gallagher, Owen; Labarre, David; Williams, Michael S; Golden, Neal J; Pouillot, Régis; Dearfield, Kerry L; Kause, Janell

    2013-04-01

    This report illustrates how the uncertainty about food safety metrics may influence the selection of a performance objective (PO). To accomplish this goal, we developed a model concerning Listeria monocytogenes in ready-to-eat (RTE) deli meats. This application used a second order Monte Carlo model that simulates L. monocytogenes concentrations through a series of steps: the food-processing establishment, transport, retail, the consumer's home and consumption. The model accounted for growth inhibitor use, retail cross contamination, and applied an FAO/WHO dose response model for evaluating the probability of illness. An appropriate level of protection (ALOP) risk metric was selected as the average risk of illness per serving across all consumed servings-per-annum and the model was used to solve for the corresponding performance objective (PO) risk metric as the maximum allowable L. monocytogenes concentration (cfu/g) at the processing establishment where regulatory monitoring would occur. Given uncertainty about model inputs, an uncertainty distribution of the PO was estimated. Additionally, we considered how RTE deli meats contaminated at levels above the PO would be handled by the industry using three alternative approaches. Points on the PO distribution represent the probability that - if the industry complies with a particular PO - the resulting risk-per-serving is less than or equal to the target ALOP. For example, assuming (1) a target ALOP of -6.41 log10 risk of illness per serving, (2) industry concentrations above the PO that are re-distributed throughout the remaining concentration distribution and (3) no dose response uncertainty, establishment PO's of -4.98 and -4.39 log10 cfu/g would be required for 90% and 75% confidence that the target ALOP is met, respectively. The PO concentrations from this example scenario are more stringent than the current typical monitoring level of an absence in 25 g (i.e., -1.40 log10 cfu/g) or a stricter criteria of absence

  6. Cyber Security Risk Evaluation of a Nuclear I&C Using BN and ET

    Directory of Open Access Journals (Sweden)

    Jinsoo Shin

    2017-04-01

    Full Text Available Cyber security is an important issue in the field of nuclear engineering because nuclear facilities use digital equipment and digital systems that can lead to serious hazards in the event of an accident. Regulatory agencies worldwide have announced guidelines for cyber security related to nuclear issues, including U.S. NRC Regulatory Guide 5.71. It is important to evaluate cyber security risk in accordance with these regulatory guides. In this study, we propose a cyber security risk evaluation model for nuclear instrumentation and control systems using a Bayesian network and event trees. As it is difficult to perform penetration tests on the systems, the evaluation model can inform research on cyber threats to cyber security systems for nuclear facilities through the use of prior and posterior information and backpropagation calculations. Furthermore, we suggest a methodology for the application of analytical results from the Bayesian network model to an event tree model, which is a probabilistic safety assessment method. The proposed method will provide insight into safety and cyber security risks.

  7. Does flood risk information held within at risk population always have a positive impact? An evaluation of the effects of French regulatory tools in Orleans

    Directory of Open Access Journals (Sweden)

    Jadot Julien

    2016-01-01

    Full Text Available French law on major risk preventive information for population setup the objective to make the citizen able to act for his own safety and to participate through his behaviour to the civil security. To reach this objective, the policymakers developed 4 regulatory tools that have to be implemented by the local authorities. These 4 tools do not meet the success factors of risk communication measures aiming at inducing behavioural adaptation to face risks. This, added to the fact that people who die in the last floods events in France lost their lives due to either a lack of knowledge of the risk or to a risk taking behaviour, led us to question the impact of the preventive information regulatory tools. For the needs of our study we developed a risk perception and behaviour scale, helping us to classify the people of our sample. Our evaluation in Orléans shows that very few people know the regulatory tools and that their impact is quite low, far from the policymakers’ expectations. This highlight the real necessity to innovate in the field of flood risk communication.

  8. A regional-scale ecological risk framework for environmental flow evaluations

    Science.gov (United States)

    O'Brien, Gordon C.; Dickens, Chris; Hines, Eleanor; Wepener, Victor; Stassen, Retha; Quayle, Leo; Fouchy, Kelly; MacKenzie, James; Graham, P. Mark; Landis, Wayne G.

    2018-02-01

    Environmental flow (E-flow) frameworks advocate holistic, regional-scale, probabilistic E-flow assessments that consider flow and non-flow drivers of change in a socio-ecological context as best practice. Regional-scale ecological risk assessments of multiple stressors to social and ecological endpoints, which address ecosystem dynamism, have been undertaken internationally at different spatial scales using the relative-risk model since the mid-1990s. With the recent incorporation of Bayesian belief networks into the relative-risk model, a robust regional-scale ecological risk assessment approach is available that can contribute to achieving the best practice recommendations of E-flow frameworks. PROBFLO is a holistic E-flow assessment method that incorporates the relative-risk model and Bayesian belief networks (BN-RRM) into a transparent probabilistic modelling tool that addresses uncertainty explicitly. PROBFLO has been developed to evaluate the socio-ecological consequences of historical, current and future water resource use scenarios and generate E-flow requirements on regional spatial scales. The approach has been implemented in two regional-scale case studies in Africa where its flexibility and functionality has been demonstrated. In both case studies the evidence-based outcomes facilitated informed environmental management decision making, with trade-off considerations in the context of social and ecological aspirations. This paper presents the PROBFLO approach as applied to the Senqu River catchment in Lesotho and further developments and application in the Mara River catchment in Kenya and Tanzania. The 10 BN-RRM procedural steps incorporated in PROBFLO are demonstrated with examples from both case studies. PROBFLO can contribute to the adaptive management of water resources and contribute to the allocation of resources for sustainable use of resources and address protection requirements.

  9. A Quantitative Measure For Evaluating Project Uncertainty Under Variation And Risk Effects

    Directory of Open Access Journals (Sweden)

    A. Chenarani

    2017-10-01

    Full Text Available The effects of uncertainty on a project and the risk event as the consequence of uncertainty are analyzed. The uncertainty index is proposed as a quantitative measure for evaluating the uncertainty of a project. This is done by employing entropy as the indicator of system disorder and lack of information. By employing this index, the uncertainty of each activity and its increase due to risk effects as well as project uncertainty changes as a function of time can be assessed. The results are implemented and analyzed for a small turbojet engine development project as the case study. The results of this study can be useful for project managers and other stakeholders for selecting the most effective risk management and uncertainty controlling method.

  10. Results of the application of the Risk Evaluation System in Radiotherapy (RESRA) in radiotherapy facilities in Mexico

    International Nuclear Information System (INIS)

    Paz G, A.; Godinez S, V.

    2013-10-01

    The present work describes the main results of the risk evaluation for some radiotherapy treatments with lineal accelerators, cobalt 60, brachytherapy of high dose rate and brachytherapy of low dose rate that are realize in Mexico. These evaluations were carried out applying the risk matrices method with the tool computer risk evaluation system in radiotherapy, accessible for the national users through internet, and developed by the Comision Nacional de Seguridad Nuclear y Salvaguardias in Mexico, in cooperation with the Forum of Ibero-American regulators. The used methodology is based on the risk matrices method that is a mathematical tool for the risk evaluation, and it was centered in the evaluation from the risk to which are exposed the patients, the occupational exposed personnel and people in general, by the mechanical faults of the treatment equipment s, bad calibrations, human errors, or any other event initiator of accidents. The events initiators of accidents are defined as those undesirable events that can produce and administration of an excessive dose or a sub-dose of the prescribed dose by the doctor, to the planned objective volume, or undesirable dose to the patient's regions or dose to occupational exposed personnel or people in general. The barriers are the actions and systems as mechanical switches, interlocks or alarms, dedicated to avoid that these accidents take place. The evaluation analysis of the risk developed by the members of the Forum for radiotherapy facilities together with the software RESRA has demonstrated to be useful in the prevention of many possible accidents that have happened in the past in other facilities and can avoid many others in the future. (Author)

  11. Risk-based methodology for USNRC inspections

    International Nuclear Information System (INIS)

    Wong, S.M.; Holahan, G.M.; Chung, J.W.; Johnson, M.R.

    1995-01-01

    This paper describes the development and trial applications of a risk-based methodology to enhance the inspection processes for US nuclear power plants. Objectives of risk-based methods to complement prescriptive engineering approaches in US Nuclear Regulatory Commission (USNRC) inspection programs are presented. Insights from time-dependent risk profiles of plant configurational from Individual Plant Evaluation (IPE) studies were integrated to develop a framework for optimizing inspection efforts in NRC regulatory initiatives. Lessons learned from NRC pilot applications of the risk-based methodology for evaluation of the effectiveness of operational risk management programs at US nuclear power plant sites are also discussed

  12. Reference manual for toxicity and exposure assessment and risk characterization. CERCLA Baseline Risk Assessment

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-03-01

    The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA, 1980) (CERCLA or Superfund) was enacted to provide a program for identifying and responding to releases of hazardous substances into the environment. The Superfund Amendments and Reauthorization Act (SARA, 1986) was enacted to strengthen CERCLA by requiring that site clean-ups be permanent, and that they use treatments that significantly reduce the volume, toxicity, or mobility of hazardous pollutants. The National Oil and Hazardous Substances Pollution Contingency Plan (NCP) (USEPA, 1985; USEPA, 1990) implements the CERCLA statute, presenting a process for (1) identifying and prioritizing sites requiring remediation and (2) assessing the extent of remedial action required at each site. The process includes performing two studies: a Remedial Investigation (RI) to evaluate the nature, extent, and expected consequences of site contamination, and a Feasibility Study (FS) to select an appropriate remedial alternative adequate to reduce such risks to acceptable levels. An integral part of the RI is the evaluation of human health risks posed by hazardous substance releases. This risk evaluation serves a number of purposes within the overall context of the RI/FS process, the most essential of which is to provide an understanding of ``baseline`` risks posed by a given site. Baseline risks are those risks that would exist if no remediation or institutional controls are applied at a site. This document was written to (1) guide risk assessors through the process of interpreting EPA BRA policy and (2) help risk assessors to discuss EPA policy with regulators, decision makers, and stakeholders as it relates to conditions at a particular DOE site.

  13. Reference manual for toxicity and exposure assessment and risk characterization. CERCLA Baseline Risk Assessment

    International Nuclear Information System (INIS)

    1995-03-01

    The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA, 1980) (CERCLA or Superfund) was enacted to provide a program for identifying and responding to releases of hazardous substances into the environment. The Superfund Amendments and Reauthorization Act (SARA, 1986) was enacted to strengthen CERCLA by requiring that site clean-ups be permanent, and that they use treatments that significantly reduce the volume, toxicity, or mobility of hazardous pollutants. The National Oil and Hazardous Substances Pollution Contingency Plan (NCP) (USEPA, 1985; USEPA, 1990) implements the CERCLA statute, presenting a process for (1) identifying and prioritizing sites requiring remediation and (2) assessing the extent of remedial action required at each site. The process includes performing two studies: a Remedial Investigation (RI) to evaluate the nature, extent, and expected consequences of site contamination, and a Feasibility Study (FS) to select an appropriate remedial alternative adequate to reduce such risks to acceptable levels. An integral part of the RI is the evaluation of human health risks posed by hazardous substance releases. This risk evaluation serves a number of purposes within the overall context of the RI/FS process, the most essential of which is to provide an understanding of ''baseline'' risks posed by a given site. Baseline risks are those risks that would exist if no remediation or institutional controls are applied at a site. This document was written to (1) guide risk assessors through the process of interpreting EPA BRA policy and (2) help risk assessors to discuss EPA policy with regulators, decision makers, and stakeholders as it relates to conditions at a particular DOE site

  14. Risks: diagnosing and eliminating

    Directory of Open Access Journals (Sweden)

    Yuriy A. Tikhomirov

    2016-01-01

    Full Text Available Objective to develop conceptual theoretical and legal provisions and scientific recommendations on the identification analysis and elimination of risk. Methods universal dialectic method of cognition as well as scientific and private research methods based on it. Results the system was researched of risks diagnostics in the legal sphere and mechanism of influencing the quotrisk situationsquot and their consequences damage to the environment and harm to society. The concept of risk in the legal sphere was formulated the author39s classification of risks in the legal sphere is presented. The rules of analysis evaluation and prevention of risks and the model risk management framework are elaborated. Scientific novelty the mechanism for the identification analysis and elimination of risk has been developed and introduced into scientific circulation the author has proposed the classification and types of risks the reasons and the conditions promoting the risk occurrence. Practical significance the provisions and conclusions of the article can be used in the scientific lawmaking and lawenforcement activity as well as in the educational process of higher educational establishments. nbsp

  15. Approaches to acceptable risk

    International Nuclear Information System (INIS)

    Whipple, C.

    1997-01-01

    Several alternative approaches to address the question open-quotes How safe is safe enough?close quotes are reviewed and an attempt is made to apply the reasoning behind these approaches to the issue of acceptability of radiation exposures received in space. The approaches to the issue of the acceptability of technological risk described here are primarily analytical, and are drawn from examples in the management of environmental health risks. These include risk-based approaches, in which specific quantitative risk targets determine the acceptability of an activity, and cost-benefit and decision analysis, which generally focus on the estimation and evaluation of risks, benefits and costs, in a framework that balances these factors against each other. These analytical methods tend by their quantitative nature to emphasize the magnitude of risks, costs and alternatives, and to downplay other factors, especially those that are not easily expressed in quantitative terms, that affect acceptance or rejection of risk. Such other factors include the issues of risk perceptions and how and by whom risk decisions are made

  16. Blended Risk Approach in Applying PSA Models to Risk-Based Regulations

    International Nuclear Information System (INIS)

    Dimitrijevic, V. B.; Chapman, J. R.

    1996-01-01

    In this paper, the authors will discuss a modern approach in applying PSA models in risk-based regulation. The Blended Risk Approach is a combination of traditional and probabilistic processes. It is receiving increased attention in different industries in the U. S. and abroad. The use of the deterministic regulations and standards provides a proven and well understood basis on which to assess and communicate the impact of change to plant design and operation. Incorporation of traditional values into risk evaluation is working very well in the blended approach. This approach is very application specific. It includes multiple risk attributes, qualitative risk analysis, and basic deterministic principles. In blending deterministic and probabilistic principles, this approach ensures that the objectives of the traditional defense-in-depth concept are not compromised and the design basis of the plant is explicitly considered. (author)

  17. Managing IT Integration Risk in Acquisitions

    DEFF Research Database (Denmark)

    Henningsson, Stefan; Kettinger, William J.

    2016-01-01

    The article discusses a framework for evaluating risk of information technology (IT) integration in acquisitions. Topics include the use of the experience of serial acquirer Trelleborg AB to show the merits of the framework for managing the risk and to determine low-risk acquisitions......, the importance of managing IT integration risk, and various risk areas for acquisition IT integration....

  18. Instruments for the assessment of suicide risk: A systematic review evaluating the certainty of the evidence.

    Directory of Open Access Journals (Sweden)

    Bo Runeson

    Full Text Available Instruments have been developed to facilitate suicide risk assessment. We aimed to evaluate the evidence for these instruments including assessment of risk of bias and diagnostic accuracy for suicide and suicide attempt.PubMed (NLM, PsycInfo, Embase, Cinahl and the Cochrane Library databases were searched until December 2014. We assessed risk of bias with QUADAS-2. The average sensitivity and specificity of each instrument was estimated and the certainty of the evidence was assessed with GRADE. We considered instruments with a sensitivity > 80% and a specificity > 50% to have sufficient diagnostic accuracy.Thirty-five relevant studies were identified but 14 were considered to have high risk of bias, leaving 21 studies evaluating altogether 15 risk assessment instruments. We could carry out meta-analyses for five instruments. For the outcome suicide attempt SAD PERSONS Scale had a sensitivity of 15% (95% CI 8-24 and specificity of 97% (96-98, and the Manchester Self-Harm Rule (MSHR a sensitivity of 97% (97-97 and a specificity of 20% (20-21. ReACT, which is a modification of MSHR, had a similar low specificity, as did the Sodersjukhuset Self Harm Rule. For the outcome suicide, the Beck Hopelessness Scale had a sensitivity of 89% (78-95 and specificity of 42% (40-43.Most suicide risk assessment instruments were supported by too few studies to allow for evaluation of accuracy. Among those that could be evaluated, none fulfilled requirements for sufficient diagnostic accuracy.

  19. The effects of infographics and several quantitative versus qualitative formats for cardiovascular disease risk, including heart age, on people's risk understanding.

    Science.gov (United States)

    Damman, Olga C; Vonk, Suzanne I; van den Haak, Maaike J; van Hooijdonk, Charlotte M J; Timmermans, Danielle R M

    2018-03-11

    To study how comprehension of cardiovascular disease (CVD) risk is influenced by: (1) infographics about qualitative risk information, with/without risk numbers; (2) which qualitative risk dimension is emphasized; (3) heart age vs. traditional risk format. For aim 1, a 2 (infographics versus text) x 2 (risk number versus no risk number) between-subjects design was used. For aim 2, three pieces of information were tested within-subjects. Aim 3 used a simple comparison group. Participants (45-65 yrs old) were recruited through an online access panel; low educated people were oversampled. They received hypothetical risk information (20%/61yrs). Primary outcomes: recall, risk appraisals, subjective/objective risk comprehension. behavioral intentions, information evaluations. Infographics of qualitative risk dimensions negatively affected recall, subjective risk comprehension and information evaluations. No effect of type of risk dimension was found on risk perception. Heart age influenced recall, comprehension, evaluations and affective risk appraisals. Infographics of hypothetical CVD risk information had detrimental effects on measures related to risk perception/comprehension, but effects were mainly seen in undereducated participants. Heart age influenced perceptions/comprehension of hypothetical risk in a way that seemed to support understanding. Heart age seems a fruitful risk communication approach in disease risk calculators. Copyright © 2018 Elsevier B.V. All rights reserved.

  20. Epidemiological geomatics in evaluation of mine risk education in Afghanistan: introducing population weighted raster maps

    Directory of Open Access Journals (Sweden)

    Andersson Neil

    2006-01-01

    Full Text Available Abstract Evaluation of mine risk education in Afghanistan used population weighted raster maps as an evaluation tool to assess mine education performance, coverage and costs. A stratified last-stage random cluster sample produced representative data on mine risk and exposure to education. Clusters were weighted by the population they represented, rather than the land area. A "friction surface" hooked the population weight into interpolation of cluster-specific indicators. The resulting population weighted raster contours offer a model of the population effects of landmine risks and risk education. Five indicator levels ordered the evidence from simple description of the population-weighted indicators (level 0, through risk analysis (levels 1–3 to modelling programme investment and local variations (level 4. Using graphic overlay techniques, it was possible to metamorphose the map, portraying the prediction of what might happen over time, based on the causality models developed in the epidemiological analysis. Based on a lattice of local site-specific predictions, each cluster being a small universe, the "average" prediction was immediately interpretable without losing the spatial complexity.

  1. Slip and fall risk on ice and snow:identification, evaluation and prevention

    OpenAIRE

    Gao, Chuansi

    2004-01-01

    Slip and fall accidents and associated injuries on ice and snow are prevalent among outdoor workers and the general public in winter in many regions of the world. To understand and tackle this multi-factorial problem, a multidisciplinary approach was used to identify and evaluate slip and fall risks, and to propose recommendations for prevention of slips and falls on icy and snowy surfaces. Objectives were to present a systems perspective of slip and fall accidents and related risk factors; t...

  2. Effects of risk communication on natural hazards on real estate owners' risk perception and risk behaviour

    Science.gov (United States)

    Buchecker, M.; Maidl, E.

    2012-04-01

    In the last decade, in most of the European countries risk maps on natural hazards have been elaborated but there is so far little experience how to efficiently communicate these maps to the public. Recently, the public authorities of Zurich informed the owners of buildings located within the hazard zone on urban flood risks The owners received official letters containing information on potential danger, the probability of flood events, constructional safety measures, and guidelines for appropriate actions in case of an immediate flood. In the cover letter they were also encouraged to achieve more detailed information about the particular risks for their building using an online accessible risk map within a geographic information system (GIS). This risk communication campaign was based on the expectation that informing citizens increases their risk awareness and that citizens aware of risks are more likely to undertake actions to protect themselves and their property. There is, however, little empirical evidence that these expected outcomes can be achieved by written forms of risk communication. With this project we aim to find out to which degree a campaign of written risk communication can shape land owners risk perception and risk behaviour, and which other factors (e.g. trust in authorities, risk, risk zone category of the building) contributed to these outcomes... In collaboration with public authorities we conducted a survey among 1500 owners of buildings in the hazard zones in Zurich (50 % in blue zone, 50 % in yellow and yellow-white zone), that is 14% of all persons who were addressed by the authorities of the city. The standardized questionnaire comprises in particular items measuring respondents' evaluation of the virtual and physical information material, the time they spent for studying the information material, the dimensions of their risk perception, their acceptability of risks and their preparedness to implement constructional and other safety

  3. Evaluation of biologic occupational risk control practices: quality indicators development and validation.

    Science.gov (United States)

    Takahashi, Renata Ferreira; Gryschek, Anna Luíza F P L; Izumi Nichiata, Lúcia Yasuko; Lacerda, Rúbia Aparecida; Ciosak, Suely Itsuko; Gir, Elucir; Padoveze, Maria Clara

    2010-05-01

    There is growing demand for the adoption of qualification systems for health care practices. This study is aimed at describing the development and validation of indicators for evaluation of biologic occupational risk control programs. The study involved 3 stages: (1) setting up a research team, (2) development of indicators, and (3) validation of the indicators by a team of specialists recruited to validate each attribute of the developed indicators. The content validation method was used for the validation, and a psychometric scale was developed for the specialists' assessment. A consensus technique was used, and every attribute that obtained a Content Validity Index of at least 0.75 was approved. Eight indicators were developed for the evaluation of the biologic occupational risk prevention program, with emphasis on accidents caused by sharp instruments and occupational tuberculosis prevention. The indicators included evaluation of the structure, process, and results at the prevention and biologic risk control levels. The majority of indicators achieved a favorable consensus regarding all validated attributes. The developed indicators were considered validated, and the method used for construction and validation proved to be effective. Copyright (c) 2010 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

  4. Evaluating the Security Risks of System Using Hidden Markov Models

    African Journals Online (AJOL)

    System security assessment tools are either restricted to manual risk evaluation methodologies that are not appropriate for real-time application or used to determine the impact of certain events on the security status of networked systems. In this paper, we determine the strength of computer systems from the perspective of ...

  5. Korean risk assessment model for breast cancer risk prediction.

    Science.gov (United States)

    Park, Boyoung; Ma, Seung Hyun; Shin, Aesun; Chang, Myung-Chul; Choi, Ji-Yeob; Kim, Sungwan; Han, Wonshik; Noh, Dong-Young; Ahn, Sei-Hyun; Kang, Daehee; Yoo, Keun-Young; Park, Sue K

    2013-01-01

    We evaluated the performance of the Gail model for a Korean population and developed a Korean breast cancer risk assessment tool (KoBCRAT) based upon equations developed for the Gail model for predicting breast cancer risk. Using 3,789 sets of cases and controls, risk factors for breast cancer among Koreans were identified. Individual probabilities were projected using Gail's equations and Korean hazard data. We compared the 5-year and lifetime risk produced using the modified Gail model which applied Korean incidence and mortality data and the parameter estimators from the original Gail model with those produced using the KoBCRAT. We validated the KoBCRAT based on the expected/observed breast cancer incidence and area under the curve (AUC) using two Korean cohorts: the Korean Multicenter Cancer Cohort (KMCC) and National Cancer Center (NCC) cohort. The major risk factors under the age of 50 were family history, age at menarche, age at first full-term pregnancy, menopausal status, breastfeeding duration, oral contraceptive usage, and exercise, while those at and over the age of 50 were family history, age at menarche, age at menopause, pregnancy experience, body mass index, oral contraceptive usage, and exercise. The modified Gail model produced lower 5-year risk for the cases than for the controls (p = 0.017), while the KoBCRAT produced higher 5-year and lifetime risk for the cases than for the controls (pKorean women, especially urban women.

  6. Risk Assessment

    OpenAIRE

    Hrdová, Edita

    2012-01-01

    This diploma thesis is focused on companies risk evaluation before endorsement of Loan deriving from business relationships. The aim of this thesis is not only to describe individual steps of risk assessment, but also perfom analysis of particular companies based on available data, i.e. Balance sheet, Profit and Loss statement and external rating and after that propose solution for each company. My analysis will be based on theoretical knowledge, further on experience related to my job role a...

  7. Using Multi-criteria Evaluation and GIS for Flood Risk Analysis in ...

    African Journals Online (AJOL)

    Using Multi-criteria Evaluation and GIS for Flood Risk Analysis in Informal ... Using a case study of an informal settlement in Cape Town, this study ... The shack outlines of the informal settlement were digitized using CTCC aerial imagery.

  8. LSST Painting Risk Evaluation Memo

    Energy Technology Data Exchange (ETDEWEB)

    Wolfe, Justin E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-11-10

    The optics subsystem is required to paint the edges of optics black where possible. Due to the risks in applying the paint LSST requests a review of the impact of removing this requirement for the filters and L3.

  9. RiskLab - a joint Teaching Lab on Hazard and Risk Management

    Science.gov (United States)

    Baruffini, Mi.; Baruffini, Mo.; Thuering, M.

    2009-04-01

    In the future natural disasters are expected to increase due to climatic changes that strongly affect environmental, social and economical systems. For this reason and because of the limited resources, governments require analytical risk analysis for a better mitigation planning. Risk analysis is a process to determine the nature and extent of risk by estimating potential hazards and evaluating existing conditions of vulnerability that could pose a potential threat or harm to people, property, livelihoods and environment. This process has become a generally accepted approach for the assessment of cost-benefit scenarios; originating from technical risks it is being applied to natural hazards for several years now in Switzerland. Starting from these premises "Risk Lab", a joint collaboration between the Institute of Earth Sciences of the University of Applied Sciences of Southern Switzerland and the Institute for Economic Research of the University of Lugano, has been started in 2006, aiming to become a competence centre about Risk Analysis and Evaluation. The main issue studied by the lab concerns the topic "What security at what price?" and the activities follow the philosophy of the integral risk management as proposed by PLANAT, that defines the process as a cycle that contains different and interrelated phases. The final aim is to change the population and technician idea about risk from "defending against danger" to "being aware of risks" through a proper academic course specially addressed to young people. In fact the most important activity of the laboratory consists in a degree course, offered both to Engineering and Architecture students of the University of Applied Sciences of Southern Switzerland and Economy Students of the University of Lugano. The course is structured in two main parts: an introductive, theoretical part, composed by class lessons, where the main aspects of natural hazards, risk perception and evaluation and risk management are presented

  10. Proposed risk evaluation guidelines for use by the DOE-AL Nuclear Explosive Safety Division in evaluating proposed shipments of nuclear components

    International Nuclear Information System (INIS)

    Just, R.A.; Love, A.F.

    1997-10-01

    The licensing requirements of 10 CFR 71 (US Code of Federal Regulations) are the primary criteria used to license proposed US Department of Energy (DOE) shipments of nuclear components. However, if a shipment cannot meet 10 CFR 71 requirements, a Transportation System Risk Assessment (TSRA) is prepared to document: (1) the degree of compliance of proposed DOE shipments of nuclear components with applicable federal regulations, and (2) the risk associated with the proposed shipments. The Nuclear Explosive Safety Division (NESD) of the Department of Energy, Albuquerque Area Office (DOE-AL) is responsible for evaluating TSRAs and for preparing Safety Evaluation Reports (SERs) to authorize the off-site transport. Hazards associated with the transport may include the presence of fissile material, chemically and radiologically toxic uranium, and ionizing radiation. The Nuclear Regulatory Commission (NRC) has historically considered only radiological hazards in licensing the transport of radiological material because the US Department of Transportation considers licensing requirements of nonradiological (i.e., chemically toxic) hazards. The requirements of 10 CFR 71 are based primarily on consideration of radiological hazards. For completeness, this report provides information for assessing the effects of chemical toxicity. Evaluating the degree of compliance with the requirements of 10 CFR 71 is relatively straightforward. However, there are few precedents associated with developing TSRA risk assessments for packages that do not comply with all of the requirements of 10 CFR 71. The objective of the task is to develop Risk Evaluation Guidelines for DOE-AL to use when evaluating a TSRA. If the TSRA shows that the Risk Evaluation Guidelines are not exceeded, then from a risk perspective the TSRA should be approved if there is evidence that the ALARA (as low as reasonably achievable) principle has been applied

  11. Vertigo and dizziness in adolescents: Risk factors and their population attributable risk.

    Science.gov (United States)

    Filippopulos, Filipp M; Albers, Lucia; Straube, Andreas; Gerstl, Lucia; Blum, Bernhard; Langhagen, Thyra; Jahn, Klaus; Heinen, Florian; von Kries, Rüdiger; Landgraf, Mirjam N

    2017-01-01

    To assess potential risk factors for vertigo and dizziness in adolescents and to evaluate their variability by different vertigo types. The role of possible risk factors for vertigo and dizziness in adolescents and their population relevance needs to be addressed in order to design preventive strategies. The study population consisted of 1482 school-children between the age of 12 and 19 years, who were instructed to fill out a questionnaire on different vertigo types and related potential risk factors. The questionnaire specifically asked for any vertigo, spinning vertigo, swaying vertigo, orthostatic dizziness, and unspecified dizziness. Further a wide range of potential risk factors were addressed including gender, stress, muscular pain in the neck and shoulder region, sleep duration, migraine, coffee and alcohol consumption, physical activity and smoking. Gender, stress, muscular pain in the neck and shoulder region, sleep duration and migraine were identified as independent risk factors following mutual adjustment: The relative risk was 1.17 [1.10-1.25] for female sex, 1.07 [1.02-1.13] for stress, 1.24 [1.17-1.32] for muscular pain, and 1.09 [1.03-1.14] for migraine. The population attributable risk explained by these risk factors was 26%, with muscular pain, stress, and migraine accounting for 11%, 4%, and 3% respectively. Several established risk factors in adults were also identified in adolescents. Risk factors amenable to prevention accounted for 17% of the total population risk. Therefore, interventions targeting these risk factors may be warranted.

  12. Proposal of a method for evaluating tsunami risk using response-surface methodology

    Science.gov (United States)

    Fukutani, Y.

    2017-12-01

    Information on probabilistic tsunami inundation hazards is needed to define and evaluate tsunami risk. Several methods for calculating these hazards have been proposed (e.g. Løvholt et al. (2012), Thio (2012), Fukutani et al. (2014), Goda et al. (2015)). However, these methods are inefficient, and their calculation cost is high, since they require multiple tsunami numerical simulations, therefore lacking versatility. In this study, we proposed a simpler method for tsunami risk evaluation using response-surface methodology. Kotani et al. (2016) proposed an evaluation method for the probabilistic distribution of tsunami wave-height using a response-surface methodology. We expanded their study and developed a probabilistic distribution of tsunami inundation depth. We set the depth (x1) and the slip (x2) of an earthquake fault as explanatory variables and tsunami inundation depth (y) as an object variable. Subsequently, tsunami risk could be evaluated by conducting a Monte Carlo simulation, assuming that the generation probability of an earthquake follows a Poisson distribution, the probability distribution of tsunami inundation depth follows the distribution derived from a response-surface, and the damage probability of a target follows a log normal distribution. We applied the proposed method to a wood building located on the coast of Tokyo Bay. We implemented a regression analysis based on the results of 25 tsunami numerical calculations and developed a response-surface, which was defined as y=ax1+bx2+c (a:0.2615, b:3.1763, c=-1.1802). We assumed proper probabilistic distribution for earthquake generation, inundation height, and vulnerability. Based on these probabilistic distributions, we conducted Monte Carlo simulations of 1,000,000 years. We clarified that the expected damage probability of the studied wood building is 22.5%, assuming that an earthquake occurs. The proposed method is therefore a useful and simple way to evaluate tsunami risk using a response

  13. Risk concept and risk management in the field of power installations

    International Nuclear Information System (INIS)

    Stein, Manfred; Barbulescu, Christiana; Anastasiu, Dan; Ionescu, Dumitru Cezar; Iliescu-Saligny, Paul; Iordache, Vasile

    1996-01-01

    The paper presents several opinions concerning general as well as specific aspects related to the risk management and the use of this concept in the field of power generation. Assessment possibilities of disturbing phenomena are analyzed including severe events leading to failures in power installations. Circumstances of occurring of such events are considered. This paper contains 4 sections. In the introduction the definition of the concept of risk is given. Risk is thus related to both events of a distinct nature with potentially dangerous consequences and events occurring in current operation of installations of different types. The risk notion is as important as other probabilistic indicators characterizing the power installation operation, i.e. availability, reliability, maintenance, etc. The section 2 approaches the concept of risk and argues for the necessity of quantifying it. Two probabilistic indicators are introduced, namely, the occurring probability of a disturbing event and the occurring frequency. To establish an algorithm of risk evaluation the risk notion should be dissociated into two components, the 'intrinsic' or 'initial' risk and the 'associated' risk. In turn, the latter could be divided into two types of risks, namely, the risk of an extant sustaining factor and the risk characterizing the exposure to the effects of the considered events. Applications of these notions for the cases of nuclear accidents, urban electricity or heating breakdown, energy supply breakdown in chemical facilities and others are given. The third section deals with risk management in power sector. Three objectives are here taken into account, i.e., ensuring the safety in operation of adopted systems, ensuring the safety of these systems from the consumers' standpoints and ensuring the environment protection. Examples for using the concepts introduced in case of electrical power stations or energy supply systems are given

  14. Issues regarding Risk Effect Analysis of Digitalized Safety Systems and Main Risk Contributors

    International Nuclear Information System (INIS)

    Kang, Hyun Gook; Jang, Seung-Cheol

    2008-01-01

    Risk factors of safety-critical digital systems affect overall plant risk. In order to assess this risk effect, a risk model of a digitalized safety system is required. This article aims to provide an overview of the issues when developing a risk model and demonstrate their effect on plant risk quantitatively. Research activities in Korea for addressing these various issues, such as the software failure probability and the fault coverage of self monitoring mechanism are also described. The main risk contributors related to the digitalized safety system were determined in a quantitative manner. Reactor protection system and engineered safety feature component control system designed as part of the Korean Nuclear I and C System project are used as example systems. Fault-tree models were developed to assess the failure probability of a system function which is designed to generate an automated signal for actuating both of the reactor trip and the complicated accident-mitigation actions. The developed fault trees were combined with a plant risk model to evaluate the effect of a digitalized system's failure on the plant risk. (authors)

  15. VALUE AT RISK - CORPORATE RISK MEASUREMENT

    Directory of Open Access Journals (Sweden)

    Anis Cecilia-Nicoleta

    2011-12-01

    Full Text Available The notion of 'risk' is used in a number of sciences. The Faculty of Law studies the risk depending on its legality. The Accident Theory applies this term to describe the damage and the disasters. One can find studies on the risks in the works of psychology, philosophy, medicine and within each of these areas the study of the risk is based on the given science subject and, of course, on their methods and approaches. Such a variety of risk study is explained by the diversity of this phenomenon. Under the market economy conditions, the risk is an essential component of any economic agent management policy, of the approach developed by this one, a strategy that depends almost entirely on individual ability and capacity to anticipate his evolution and to exploit his opportunities, assuming a so-called 'risk of business failure.' There are several ways to measure the risks in projects, one of the most used methods to measure this being the Value at Risk(VaR. Value at Risk (VaR was made famous by JP Morgan in the mid 1990s, by introducing the RiskMetrics approach, and hence, by far, has been sanctioned by several Governing Bodies throughout the world bank. In short, it measures the value of risk capital stocks in a given period at a certain probability of loss. This measurement can be modified for risk applications through, for example, the potential loss values affirmation in a certain amount of time during the economic life of the project- clearly, a project with a lower VaR is better. It should be noted that it is not always possible or advisable for a company to limit itself to the remote analysis of each risk because the risks and their effects are interdependent and constitute a system .In addition, there are risks which, in combination with other risks, tend to produce effects which they would not have caused by themselves and risks that tend to offset and even cancel each other out.

  16. Water risk assessment in China based on the improved Water Risk Filter

    Science.gov (United States)

    Hong, G.; Yaqin, Q.; Qiong, L.; Cunwen, N.; Na, W.; Jiajia, L.; Jongde, G.; Na, Z.; Xiangyi, D.

    2014-09-01

    Finding an effective way to deal with the water crisis and the relationship between water and development is a major issue for all levels of government and different economic sectors across the world. Scientific understanding of water risk is the basis for achieving a scientific relationship between water and development, and water risk assessment is currently an important research focus. To effectively deal with the global water crisis, the World Wide Fund for Nature and German Investment and Development Company Limited proposed the concept of water risk and released an online Water Risk Filter in March 2012, which has been applied to at least 85 countries. To comprehensively and accurately reflect the situation of water risk in China, this study adjusts the water risk assessment indicators in the Water Risk Filter, taking the actual situation in China and the difficulty of obtaining the information about the indicators into account, and proposes an index system for water risk evaluation for China which consists of physical risk, regulatory risk and reputational risk. The improved Water Risk Filter is further used to assess the sources and causes of the water risks in 10 first-class and seven second-class water resource areas (WRAs). The results indicate that the water risk for the whole country is generally medium and low, while those for different regions in the country vary greatly, and those for southern regions are generally lower than those for northern regions. Government regulatory and policy implementation as well as media supervision in northern regions should be strengthened to reduce the water risk. The research results may provide decision support and references for both governments and industrial enterprises in identifying water risks, formulating prevention and control policies, and improving water resources management in China.

  17. Water risk assessment in China based on the improved Water Risk Filter

    Directory of Open Access Journals (Sweden)

    G. Hong

    2014-09-01

    Full Text Available Finding an effective way to deal with the water crisis and the relationship between water and development is a major issue for all levels of government and different economic sectors across the world. Scientific understanding of water risk is the basis for achieving a scientific relationship between water and development, and water risk assessment is currently an important research focus. To effectively deal with the global water crisis, the World Wide Fund for Nature and German Investment and Development Company Limited proposed the concept of water risk and released an online Water Risk Filter in March 2012, which has been applied to at least 85 countries. To comprehensively and accurately reflect the situation of water risk in China, this study adjusts the water risk assessment indicators in the Water Risk Filter, taking the actual situation in China and the difficulty of obtaining the information about the indicators into account, and proposes an index system for water risk evaluation for China which consists of physical risk, regulatory risk and reputational risk. The improved Water Risk Filter is further used to assess the sources and causes of the water risks in 10 first-class and seven second-class water resource areas (WRAs. The results indicate that the water risk for the whole country is generally medium and low, while those for different regions in the country vary greatly, and those for southern regions are generally lower than those for northern regions. Government regulatory and policy implementation as well as media supervision in northern regions should be strengthened to reduce the water risk. The research results may provide decision support and references for both governments and industrial enterprises in identifying water risks, formulating prevention and control policies, and improving water resources management in China.

  18. Decisions under risk in Parkinson's disease: preserved evaluation of probability and magnitude.

    Science.gov (United States)

    Sharp, Madeleine E; Viswanathan, Jayalakshmi; McKeown, Martin J; Appel-Cresswell, Silke; Stoessl, A Jon; Barton, Jason J S

    2013-11-01

    Unmedicated Parkinson's disease patients tend to be risk-averse while dopaminergic treatment causes a tendency to take risks. While dopamine agonists may result in clinically apparent impulse control disorders, treatment with levodopa also causes shift in behaviour associated with an enhanced response to rewards. Two important determinants in decision-making are how subjects perceive the magnitude and probability of outcomes. Our objective was to determine if patients with Parkinson's disease on or off levodopa showed differences in their perception of value when making decisions under risk. The Vancouver Gambling task presents subjects with a choice between one prospect with larger outcome and a second with higher probability. Eighteen age-matched controls and eighteen patients with Parkinson's disease before and after levodopa were tested. In the Gain Phase subjects chose between one prospect with higher probability and another with larger reward to maximize their gains. In the Loss Phase, subjects played to minimize their losses. Patients with Parkinson's disease, on or off levodopa, were similar to controls when evaluating gains. However, in the Loss Phase before levodopa, they were more likely to avoid the prospect with lower probability but larger loss, as indicated by the steeper slope of their group psychometric function (t(24) = 2.21, p = 0.04). Modelling with prospect theory suggested that this was attributable to a 28% overestimation of the magnitude of loss, rather than an altered perception of its probability. While pre-medicated patients with Parkinson's disease show risk-aversion for large losses, patients on levodopa have normal perception of magnitude and probability for both loss and gain. The finding of accurate and normally biased decisions under risk in medicated patients with PD is important because it indicates that, if there is indeed anomalous risk-seeking behaviour in such a cohort, it may derive from abnormalities in components of

  19. Holistic seismic risk assessment of port of Spain: an integrated evaluation and tool in the framework of CAPRA

    OpenAIRE

    Carreño Tibaduiza, Martha Liliana; Cardona Arboleda, Omar Dario; Barbat Barbat, Horia Alejandro; Velasquez, Cesar A.; Salgado Galvez, Mario A.

    2014-01-01

    In recent years disaster risk has been defined, for management purposes, as the potential economic, social and environmental consequences of hazardous events that may occur in a given period of time. However, in many cases, the concept of risk has been defined in a fragmentary way according to each scientific discipline involved in its estimation. In order to evaluate risk according to the above stated definition, a multidisciplinary evaluation is necessary. This evaluation should take into a...

  20. Research items regarding seismic residual risk evaluation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-08-15

    After learning the Fukushima Dai-ichi NPP severe accidents in 2011, the government investigation committee proposed the effective use of probabilistic safety assessment (PSA), and now it is required to establish new safety rules reflecting the results of probabilistic risk assessment (PRA) and proposed severe accident measures. Since the Seismic Design Guide has been revised on September 19, 2006, JNES has been discussing seismic PRA (Levels 1-3) methods to review licensees' residual risk assessment while preparing seismic PRA models. Meanwhile, new safety standards for light water reactors are to be issued and enforced on July 2013, which require the residual risk of tsunami, in addition to earthquakes, should be lowered as much as possible. The Fukushima accidents raised the problems related to risk assessment, e.g. approaches based on multi-hazard (earthquake and tsunami), multi-unit, multi-site, and equipment's common cause failure. This fiscal year, while performing seismic and/or tsunami PRA to work on these problems, JNES picked up the equipment whose failure greatly contribute to core damage, surveyed accident management measures on those equipment as well as effectiveness to reduce core damage probability. (author)

  1. A case study for evaluating ecological risks at the Idaho National Engineering Laboratory (INEL)

    International Nuclear Information System (INIS)

    Peterson, S.; Brewer, R.; Morris, R.; VanHorn, R.

    1994-01-01

    A case study was conducted as a component of the development of guidance for ecological risk assessment at the Department of Energy's Idaho National Engineering Laboratory (INEL). The INEL is a large facility in southeastern Idaho, encompassing expanses of sagebrush-steppe that harbor numerous wildlife species. Nuclear research and waste disposal activities have resulted in releases of radionuclides at various sites. Due to the size and number of potentially contaminated areas, a cost-effective method was needed to evaluate ecological risks and to identify data needs for remedial investigations. Screening-level assessment approaches were developed to evaluate data collected from previous site investigations. Above-background concentrations of radionuclides and other contaminants in media were compared to risk-based criteria, which were derived from sources such as recent publications of the International Atomic Energy Agency (IAEA) and National Council on Radiation Protection and Measurements (NCRP). Site-specific risks to plants and wildlife were estimated for contaminants exceeding criteria. Dose rates derived using various estimation methods were compared to reference doses for wildlife obtained from IAEA, NCRP, and other publications

  2. Research on Liquidity Risk Evaluation of Chinese A-Shares Market Based on Extension Theory

    Science.gov (United States)

    Bai-Qing, Sun; Peng-Xiang, Liu; Lin, Zhang; Yan-Ge, Li

    This research defines the liquidity risk of stock market in matter-element theory and affair-element theory, establishes the indicator system of the forewarning for liquidity risks,designs the model and the process of early warning using the extension set method, extension dependent function and the comprehensive evaluation model. And the paper studies empirically A-shares market through the data of 1A0001, which prove that the model can better describe liquidity risk of China’s A-share market. At last, it gives the corresponding policy recommendations.

  3. Evaluation of the sanitary and environmental risks resulting from the Erika sinking and from the coasts cleaning operations

    International Nuclear Information System (INIS)

    Cicolella, A.

    2000-03-01

    This synthesis presents the methodology of the risks evaluation and of the INERIS report, the products analysis, general data on polycyclic aromatic hydrocarbons, the exposure evaluation, the sanitary impact evaluation for the polycyclic organic hydrocarbons and volatile organic compounds and the evaluation of ecological risks. (A.L.B.)

  4. PRE-MARKET CLINICAL EVALUATIONS OF INNOVATIVE HIGH-RISK MEDICAL DEVICES IN EUROPE

    DEFF Research Database (Denmark)

    Hulstaert, F.; Neyt, M.; Vinck, I.

    2012-01-01

    data are available? We studied the premarket clinical evaluation of innovative high-risk medical devices in Europe compared with the US, and with medicines, where appropriate. Methods: The literature and regulatory documents were checked. Representatives from industry, Competent Authorities, Notified...... of premarket trials in Europe and number of patients exposed, but failed as this information is not made public. Furthermore, the Helsinki Declaration is not followed with respect to the registration and publication of premarket trials. Conclusions: For innovative high-risk devices, new EU legislation should...

  5. Post-Flight Back Pain Following International Space Station Missions: Evaluation of Spaceflight Risk Factors

    Science.gov (United States)

    Laughlin, M. S.; Murray, J. D.; Wear, M. L.; Van Baalen, M.

    2016-01-01

    INTRODUCTION Back pain during spaceflight has often been attributed to the lengthening of the spinal column due to the absence of gravity during both short and long-duration missions. Upon landing and re-adaptation to gravity, the spinal column reverts back to its original length thereby causing some individuals to experience pain and muscular spasms, while others experience no ill effects. With International Space Station (ISS) missions, cases of back pain and injury are more common post-flight, but little is known about the potential risk factors. Thus, the purpose of this project was to perform an initial evaluation of reported post-flight back pain and injury cases to relevant spaceflight risk factors in United States astronauts that have completed an ISS mission. METHODS All US astronauts who completed an ISS mission between Expeditions (EXP) 1 and 41 (2000-2015) were included in this evaluation. Forty-five astronauts (36 males and 9 females) completed 50 ISS missions during the study time period, as 5 astronauts completed 2 ISS missions. Researchers queried medical records of the 45 astronauts for occurrences of back pain and injury. A case was defined as any reported event of back pain or injury to the cervical, thoracic, lumbar, sacral, or coccyx spine regions. Data sources for the cases included the Flight Medicine Clinic's electronic medical record; Astronaut Strength, Conditioning and Rehabilitation electronic documentation; the Private Medical Conference tool; and the Space Medicine Operations Team records. Post-flight cases were classified as an early case if reported within 45 days of landing (R + 45) or a late case if reported from R + 46 to R + 365 days after landing (R + 1y). Risk factors in the astronaut population for back pain include age, sex, prior military service, and prior history of back pain. Additionally, spaceflight specific risk factors such as type of landing vehicle and onboard exercise countermeasures were included to evaluate their

  6. Risk uncertainty analysis methods for NUREG-1150

    International Nuclear Information System (INIS)

    Benjamin, A.S.; Boyd, G.J.

    1987-01-01

    Evaluation and display of risk uncertainties for NUREG-1150 constitute a principal focus of the Severe Accident Risk Rebaselining/Risk Reduction Program (SARRP). Some of the principal objectives of the uncertainty evaluation are: (1) to provide a quantitative estimate that reflects, for those areas considered, a credible and realistic range of uncertainty in risk; (2) to rank the various sources of uncertainty with respect to their importance for various measures of risk; and (3) to characterize the state of understanding of each aspect of the risk assessment for which major uncertainties exist. This paper describes the methods developed to fulfill these objectives

  7. How are the catastrophical risks quantifiable

    International Nuclear Information System (INIS)

    Chakraborty, S.

    1985-01-01

    For the assessment and evaluation of industrial risks the question must be asked how are the catastrophical risks quantifiable. Typical real catastrophical risks and risk assessment based on modelling assumptions have been placed against each other in order to put the risks into proper perspective. However, the society is risk averse when there is a catastrophic potential of severe accidents in a large scale industrial facility even though there is extremely low probability of occurence. (orig.) [de

  8. Is risk analysis scientific?

    Science.gov (United States)

    Hansson, Sven Ove; Aven, Terje

    2014-07-01

    This article discusses to what extent risk analysis is scientific in view of a set of commonly used definitions and criteria. We consider scientific knowledge to be characterized by its subject matter, its success in developing the best available knowledge in its fields of study, and the epistemic norms and values that guide scientific investigations. We proceed to assess the field of risk analysis according to these criteria. For this purpose, we use a model for risk analysis in which science is used as a base for decision making on risks, which covers the five elements evidence, knowledge base, broad risk evaluation, managerial review and judgment, and the decision; and that relates these elements to the domains experts and decisionmakers, and to the domains fact-based or value-based. We conclude that risk analysis is a scientific field of study, when understood as consisting primarily of (i) knowledge about risk-related phenomena, processes, events, etc., and (ii) concepts, theories, frameworks, approaches, principles, methods and models to understand, assess, characterize, communicate, and manage risk, in general and for specific applications (the instrumental part). © 2014 Society for Risk Analysis.

  9. Evaluation Of The Risk Of Financing Projects Of Environmental Protection

    Directory of Open Access Journals (Sweden)

    Gabriela Cornelia PICIU

    2012-03-01

    Full Text Available The research project approaches multidimensionally the financing of environmental protection from the perspective of directing, correlating and consolidating the financial flows circumscribed to the regeneration of an economy affected by environmental deterioration due to the very activities defining the economic mechanisms and circuits. The purpose of the project is to identify, by scientific, methodological and empirical analysis of the concepts, principles and arguments imposed by the economic theory, the risks of financing the projects of environmental projects and to evaluate their effects because their neglecting, individual approach or erroneous dimensioning might have unfavourable and unforeseen consequences in terms of the efficiency of the environmental strategies and policies. The objective of the study is the reveal the interdependency and interaction between the flows and circuits financing the environmental projects, showing the necessity for punctual, distributive, correlative and multiplicative financing of the environmental protection. This must be done from an expanded and prospective spatial and temporal vision by a compositional approach of the risk for environmental investments within the complex network of the social, economic and financial risks generated by the global system of the human praxis focused on the binomial of the human-environment interdependence.

  10. Risk perception for paragliding practitioners.

    OpenAIRE

    Paixão, Jairo Antônio da; Tucher, Guilherme

    2012-01-01

    As an adventure sport, paragliding exposes participants to different levels of life risk. However, the boundary between calculated risk and real risk is a subtle one, depending on the practitioner’s perception. Thus, this study aimed to analyze risk perception of 73 paragliding practitioners. The descriptive-exploratory study method was used. Data was col-lected via a questionnaire validated according to the Delphi technique. Variables were evaluated from a bipolar Likert type scale, ranging ...

  11. Practical Methods for Information Security Risk Management

    Directory of Open Access Journals (Sweden)

    Cristian AMANCEI

    2011-01-01

    Full Text Available The purpose of this paper is to present some directions to perform the risk man-agement for information security. The article follows to practical methods through question-naire that asses the internal control, and through evaluation based on existing controls as part of vulnerability assessment. The methods presented contains all the key elements that concurs in risk management, through the elements proposed for evaluation questionnaire, list of threats, resource classification and evaluation, correlation between risks and controls and residual risk computation.

  12. The total theory about risk management

    International Nuclear Information System (INIS)

    Furuya, Shunsuke

    2003-01-01

    A general working procedure of risk management, some example of other countries, topics and problems in the future are described. A definition of risk, risk assessment, risk management process, setting of aim and definite policy are explained. As a fundamental way of thinking, risk is controlled by ALARP (As Low As Reasonably Practicable). The upper and lower limit of risk level is called as Quantitative Safety Goal and Target Level of Safety, respectively. These limits in the atomic power and airplane are decided. Evaluation of risk, countermeasure and practice are explained. For example, a permissible range of risk and practical use in England, U.S.A, Holland and Japan are stated. Recently, accountability risk, missing demand risk and control risk are important. (S.Y.)

  13. Vertigo and dizziness in adolescents: Risk factors and their population attributable risk.

    Directory of Open Access Journals (Sweden)

    Filipp M Filippopulos

    Full Text Available To assess potential risk factors for vertigo and dizziness in adolescents and to evaluate their variability by different vertigo types. The role of possible risk factors for vertigo and dizziness in adolescents and their population relevance needs to be addressed in order to design preventive strategies.The study population consisted of 1482 school-children between the age of 12 and 19 years, who were instructed to fill out a questionnaire on different vertigo types and related potential risk factors. The questionnaire specifically asked for any vertigo, spinning vertigo, swaying vertigo, orthostatic dizziness, and unspecified dizziness. Further a wide range of potential risk factors were addressed including gender, stress, muscular pain in the neck and shoulder region, sleep duration, migraine, coffee and alcohol consumption, physical activity and smoking.Gender, stress, muscular pain in the neck and shoulder region, sleep duration and migraine were identified as independent risk factors following mutual adjustment: The relative risk was 1.17 [1.10-1.25] for female sex, 1.07 [1.02-1.13] for stress, 1.24 [1.17-1.32] for muscular pain, and 1.09 [1.03-1.14] for migraine. The population attributable risk explained by these risk factors was 26%, with muscular pain, stress, and migraine accounting for 11%, 4%, and 3% respectively.Several established risk factors in adults were also identified in adolescents. Risk factors amenable to prevention accounted for 17% of the total population risk. Therefore, interventions targeting these risk factors may be warranted.

  14. Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking.

    Directory of Open Access Journals (Sweden)

    Ian C Scott

    Full Text Available The improved characterisation of risk factors for rheumatoid arthritis (RA suggests they could be combined to identify individuals at increased disease risks in whom preventive strategies may be evaluated. We aimed to develop an RA prediction model capable of generating clinically relevant predictive data and to determine if it better predicted younger onset RA (YORA. Our novel modelling approach combined odds ratios for 15 four-digit/10 two-digit HLA-DRB1 alleles, 31 single nucleotide polymorphisms (SNPs and ever-smoking status in males to determine risk using computer simulation and confidence interval based risk categorisation. Only males were evaluated in our models incorporating smoking as ever-smoking is a significant risk factor for RA in men but not women. We developed multiple models to evaluate each risk factor's impact on prediction. Each model's ability to discriminate anti-citrullinated protein antibody (ACPA-positive RA from controls was evaluated in two cohorts: Wellcome Trust Case Control Consortium (WTCCC: 1,516 cases; 1,647 controls; UK RA Genetics Group Consortium (UKRAGG: 2,623 cases; 1,500 controls. HLA and smoking provided strongest prediction with good discrimination evidenced by an HLA-smoking model area under the curve (AUC value of 0.813 in both WTCCC and UKRAGG. SNPs provided minimal prediction (AUC 0.660 WTCCC/0.617 UKRAGG. Whilst high individual risks were identified, with some cases having estimated lifetime risks of 86%, only a minority overall had substantially increased odds for RA. High risks from the HLA model were associated with YORA (P<0.0001; ever-smoking associated with older onset disease. This latter finding suggests smoking's impact on RA risk manifests later in life. Our modelling demonstrates that combining risk factors provides clinically informative RA prediction; additionally HLA and smoking status can be used to predict the risk of younger and older onset RA, respectively.

  15. Improving flood risk mapping in Italy: the FloodRisk open-source software

    Science.gov (United States)

    Albano, Raffaele; Mancusi, Leonardo; Craciun, Iulia; Sole, Aurelia; Ozunu, Alexandru

    2017-04-01

    Time and again, floods around the world illustrate the devastating impact they can have on societies. Furthermore, the expectation that the flood damages can increase over time with climate, land-use change and social growth in flood prone-areas has raised the public and other stakeholders' (governments, international organization, re-insurance companies and emergency responders) awareness for the need to manage risks in order to mitigate their causes and consequences. In this light, the choice of appropriate measures, the assessment of the costs and effects of such measures, and their prioritization are crucial for decision makers. As a result, a priori flood risk assessment has become a key part of flood management practices with the aim of minimizing the total costs related to the risk management cycle. In this context, The EU Flood Directive 2007/60 requires the delineation of flood risk maps on the bases of most appropriate and advanced tools, with particular attention on limiting required economic efforts. The main aim of these risk maps is to provide the required knowledge for the development of flood risk management plans (FRMPs) by considering both costs and benefits of alternatives and results from consultation with all interested parties. In this context, this research project developed a free and open-source (FOSS) GIS software, called FloodRisk, to operatively support stakeholders in their compliance with the FRMPs. FloodRisk aims to facilitate the development of risk maps and the evaluation and management of current and future flood risk for multi-purpose applications. This new approach overcomes the limits of the expert-drive qualitative (EDQ) approach currently adopted in several European countries, such as Italy, which does not permit a suitable evaluation of the effectiveness of risk mitigation strategies, because the vulnerability component cannot be properly assessed. Moreover, FloodRisk is also able to involve the citizens in the flood

  16. Optimal fuel-mix in CHP plants under a stochastic permit price. Risk-neutrality versus risk-aversion

    International Nuclear Information System (INIS)

    Lappi, Pauli; Ollikka, Kimmo; Ollikainen, Markku

    2010-01-01

    This paper studies the optimal fuel-mix of a CHP producer under emission permit price risk. The producer's multi-fuel plant uses two CO 2 -intensive fuels and one clean fuel. Using a mean-variance framework we develop three models. The models are divided into spot-models (risk neutral and risk averse cases) and a forward-model (risk averse case). We derive the effects of price risk on optimal fuel use. An increase in price risk can in fact increase the use of CO 2 -intensive fuel in the spot-model. In the forward-model, the production and financial decisions are separate. We also evaluate the risk-bearing behavior of seven Finnish CHP producers. We found that risk-neutrality describes behavior better than risk-aversion. (author)

  17. Forecasting risk along a river basin using a probabilistic and deterministic model for environmental risk assessment of effluents through ecotoxicological evaluation and GIS.

    Science.gov (United States)

    Gutiérrez, Simón; Fernandez, Carlos; Barata, Carlos; Tarazona, José Vicente

    2009-12-20

    This work presents a computer model for Risk Assessment of Basins by Ecotoxicological Evaluation (RABETOX). The model is based on whole effluent toxicity testing and water flows along a specific river basin. It is capable of estimating the risk along a river segment using deterministic and probabilistic approaches. The Henares River Basin was selected as a case study to demonstrate the importance of seasonal hydrological variations in Mediterranean regions. As model inputs, two different ecotoxicity tests (the miniaturized Daphnia magna acute test and the D.magna feeding test) were performed on grab samples from 5 waste water treatment plant effluents. Also used as model inputs were flow data from the past 25 years, water velocity measurements and precise distance measurements using Geographical Information Systems (GIS). The model was implemented into a spreadsheet and the results were interpreted and represented using GIS in order to facilitate risk communication. To better understand the bioassays results, the effluents were screened through SPME-GC/MS analysis. The deterministic model, performed each month during one calendar year, showed a significant seasonal variation of risk while revealing that September represents the worst-case scenario with values up to 950 Risk Units. This classifies the entire area of study for the month of September as "sublethal significant risk for standard species". The probabilistic approach using Monte Carlo analysis was performed on 7 different forecast points distributed along the Henares River. A 0% probability of finding "low risk" was found at all forecast points with a more than 50% probability of finding "potential risk for sensitive species". The values obtained through both the deterministic and probabilistic approximations reveal the presence of certain substances, which might be causing sublethal effects in the aquatic species present in the Henares River.

  18. Breast cancer risks and risk prediction models.

    Science.gov (United States)

    Engel, Christoph; Fischer, Christine

    2015-02-01

    BRCA1/2 mutation carriers have a considerably increased risk to develop breast and ovarian cancer. The personalized clinical management of carriers and other at-risk individuals depends on precise knowledge of the cancer risks. In this report, we give an overview of the present literature on empirical cancer risks, and we describe risk prediction models that are currently used for individual risk assessment in clinical practice. Cancer risks show large variability between studies. Breast cancer risks are at 40-87% for BRCA1 mutation carriers and 18-88% for BRCA2 mutation carriers. For ovarian cancer, the risk estimates are in the range of 22-65% for BRCA1 and 10-35% for BRCA2. The contralateral breast cancer risk is high (10-year risk after first cancer 27% for BRCA1 and 19% for BRCA2). Risk prediction models have been proposed to provide more individualized risk prediction, using additional knowledge on family history, mode of inheritance of major genes, and other genetic and non-genetic risk factors. User-friendly software tools have been developed that serve as basis for decision-making in family counseling units. In conclusion, further assessment of cancer risks and model validation is needed, ideally based on prospective cohort studies. To obtain such data, clinical management of carriers and other at-risk individuals should always be accompanied by standardized scientific documentation.

  19. Evaluation of severe accident risks, Grand Gulf, Unit 1: Appendices

    International Nuclear Information System (INIS)

    Brown, T.D.; Breeding, R.J.; Jow, H.N.; Higgins, S.J.; Shiver, A.W.; Helton, J.C.; Amos, C.N.

    1990-12-01

    In support of the Nuclear Regulatory Commission's (NRC's) assessment of the risk from severe accidents at commercial nuclear power plants in the US report in NUREG-1150, the Severe Accident Risk Reduction Program (SARRP) has completed a revised calculation of the risk to the general public from severe accidents at the Grand Gulf Nuclear Station, Unit 1. This power plant, located in Port Gibson, Mississippi, is operated by the System Energy Resources, Inc. (SERI). The emphasis in this risk analysis was not on determining a ''so-called'' point estimate of risk. Rather, it was to determine the distribution of risk, and to discover the uncertainties that account for the breadth of this distribution. Off-site risk initiated by events internal to the power plant was assessed. This document provides Appendices A through E for this report. Topics included are, respectively: supporting information for the accident progression analysis; supporting information for the source term analysis; supporting information for the consequence analysis; risk results; and sampling information

  20. Risk analysis of industrial plants operation

    International Nuclear Information System (INIS)

    Hubert, Philippe

    1989-12-01

    This study examines the possibilities of systematic technology risk analysis in view of territorial management (city, urban community, region), including chronic and accidental risks. The objective was to relate this evaluation with those done for permanent water and air pollution. Risk management for pollution are done for a long time. A number of studies were done in urban communities and regions both for air and water pollution. The second objective is related to management of industrial risks: nuclear, petrochemical, transport of hazardous material, pipelines, etc. At the beginning, three possibilities of effects are taken into account: human health, economic aspect and water, and possibilities of evaluation are identified. Elements of risk identification are presented for quantification of results [fr

  1. Responsibility, guilt, and decision under risk.

    Science.gov (United States)

    Mancini, Francesco; Gangemi, Amelia

    2003-12-01

    We hypothesize that individuals' choices (risk-seeking/risk-aversion) depend on moral values and, in particular, on how subjects evaluate themselves as guilty or as victims of a wrong rather than on the descriptions of the outcomes as given in the options and evaluated accordingly as gains or losses (framing effect). People who evaluate themselves as victims are expected to show a risk-seeking preference (context of innocence). People who evaluate themselves as guilty are expected to show a risk-averse preference (context of guilt). Responses of 232 participants to a decision problem were compared in four different conditions involving two-story formats (innocence/guilt) and two-question-options formats (gain/loss). Regardless of the format of the question options, the story format appears to be an important determinant of individuals' preferences.

  2. Risk evaluation of uranium mining: a new kinetic approach

    Energy Technology Data Exchange (ETDEWEB)

    Scislewski, Alexandro [Brazilian Nuclear Energy Comission (CNEN), Avenida Santana, 680, Centro, Caetite-Bahia, 46400-000 (Brazil); Zuddas, Pierpaolo [Universite Pierre et Marie Curie, Paris-Sorbonne, ISTEP place Jussieu, Tour 56-55, case 116, F75252 Paris Cedex 05 (France)

    2013-07-01

    Release of uranium and associated heavy metals is the main environmental concern regarding exploitation and processing of U-ore. Increasing uranium mining activities potentially increase the risks linked to radiation exposure. As a tool to evaluate these risks, a geochemical inverse modeling approach was developed to estimate the water-mineral interaction in the presence of uranium. Our methodology is based on the estimation of dissolution rate and reactive surface area of the different minerals participating in the reaction by reconstructing the chemical evolution of the interacting fluids. We found that the reactive surface area of parent-rock minerals changes over several orders of magnitude during the investigated reaction time. We propose that the formation of coatings on dissolving mineral surfaces significantly reduces reactivity. Our results show that negatively charged uranium complexes decrease when alkalinity and rock buffer capacity is similarly lower, indicating that the dissolved carbonate is an important parameter impacting uranium mobility. (authors)

  3. Risk evaluation of uranium mining: a new kinetic approach

    International Nuclear Information System (INIS)

    Scislewski, Alexandro; Zuddas, Pierpaolo

    2013-01-01

    Release of uranium and associated heavy metals is the main environmental concern regarding exploitation and processing of U-ore. Increasing uranium mining activities potentially increase the risks linked to radiation exposure. As a tool to evaluate these risks, a geochemical inverse modeling approach was developed to estimate the water-mineral interaction in the presence of uranium. Our methodology is based on the estimation of dissolution rate and reactive surface area of the different minerals participating in the reaction by reconstructing the chemical evolution of the interacting fluids. We found that the reactive surface area of parent-rock minerals changes over several orders of magnitude during the investigated reaction time. We propose that the formation of coatings on dissolving mineral surfaces significantly reduces reactivity. Our results show that negatively charged uranium complexes decrease when alkalinity and rock buffer capacity is similarly lower, indicating that the dissolved carbonate is an important parameter impacting uranium mobility. (authors)

  4. The usefulness of myocardial SPECT for the preoperative cardiac risk evaluation in noncardiac surgery

    International Nuclear Information System (INIS)

    Lim, Seok Tae; Lee, Dong Soo; Kang, Won Jon; Chung, June Key; Lee, Myung Chul

    1999-01-01

    We investigated whether myocardial SPECT had additional usefulness to clinical, functional or surgical indices for the preoperative evaluation of cardiac risks in noncardiac surgery. 118 patients ( M: F=66: 52, 62.7±10.5 years) were studied retrospectively. Eighteen underwent vascular surgeries and 100 nonvascular surgeries. Rest Tl-201/ stress Tc-99m-MIBI SPECT was performed before operation and cardiac events (hard event: cardiac death and myocardial infarction; soft event: ischemic ECG change, congestive heat failure and unstable angina) were surveyed through perioperative periods (14.6±5.6 days). Clinical risk indices, functional capacity, surgery procedures and SPECT findings were tested for their predictive values of perioperative cardiac events. Peri-operative cardiac events occurred in 25 patients (3 hard events and 22 soft events). Clinical risk indices, surgical procedure risks and SPECT findings but functional capacity were predictive of cardiac events. Reversible perfusion decrease was a better predictor than persistent decrease. Multivariate analysis sorted out surgical procedure risk (p=0.0018) and SPECT findings (p=0.0001) as significant risk factors. SPECT could re-stratify perioperative cardiac risks in patients ranked with surgical procedures. We conclude that myocardial SPECT provides additional predictive value to surgical type risks as well as clinical indexes or functional capacity for the prediction of preoperative cardiac events in noncardiac surgery

  5. Occupational risk of building construction

    International Nuclear Information System (INIS)

    Aneziris, O.N.; Topali, E.; Papazoglou, I.A.

    2012-01-01

    This paper presents the quantification of occupational risk of a building construction project. Risk assessment is based on the Occupational Risk Model (ORCA) developed under the Workgroup Occupational Risk Model project (WORM), in the Netherlands, for quantifying occupational risk. This model assesses occupational risk of a worker, by taking into account his various tasks, activities and their hazards. Risk is evaluated for three types of consequences: recoverable injury, permanent injury and death. The occupational risk model is based on a set of 63 bowties, which assess risk owing to different hazards such as fall from ladder, scaffold, roofs, falling object, struck by moving vehicle, contact by moving parts, etc. ORCA calculates the risk profile of a building construction site, consisting of thirty-eight workers in different job positions, such as operators of excavators, loaders, compaction equipment, workers in excavation and framing phases, etc. All risk profiles of workers have been quantified and jobs have been ranked according to their risk. Workers installing timber formworks have the highest fatality risk (1.57×10 −3 /yr), followed by the workers installing reinforcement (1.52×10 −3 /yr).

  6. Strategies for continuous evaluation of the benefit-risk profile of HPV-16/18-AS04-adjuvanted vaccine.

    Science.gov (United States)

    Angelo, Maria-Genalin; Taylor, Sylvia; Struyf, Frank; Tavares Da Silva, Fernanda; Arellano, Felix; David, Marie-Pierre; Dubin, Gary; Rosillon, Dominique; Baril, Laurence

    2014-11-01

    The HPV types 16/18-AS04-adjuvanted cervical cancer vaccine, Cervarix(®) (HPV-16/18-vaccine, GlaxoSmithKline, Belgium) was first approved in 2007 and is licensed in 134 countries for the prevention of persistent infection, premalignant cervical lesions and cervical cancer caused by oncogenic HPV. Benefit-risk status requires continual re-evaluation as vaccine uptake increases, as the epidemiology of the disease evolves and as new information becomes available. This paper provides an example of benefit-risk considerations and risk-management planning. Evaluation of the benefit-risk of HPV-16/18-vaccine post-licensure includes studies with a range of designs in many countries and in collaboration with national public agencies and regulatory authorities. The strategy to assess benefit versus risk will continue to evolve and adapt to the changing HPV-16/18-vaccine market.

  7. Comprehensive safeguards evaluation methods and societal risk analysis

    International Nuclear Information System (INIS)

    Richardson, J.M.

    1982-03-01

    Essential capabilities of an integrated evaluation methodology for analyzing safeguards systems are discussed. Such a methodology must be conceptually meaningful, technically defensible, discriminating and consistent. A decompostion of safeguards systems by function is mentioned as a possible starting point for methodology development. The application of a societal risk equation to safeguards systems analysis is addressed. Conceptual problems with this approach are discussed. Technical difficulties in applying this equation to safeguards systems are illustrated through the use of confidence intervals, information content, hypothesis testing and ranking and selection procedures

  8. Changing Global Risk Landscape - Challenges for Risk Management (Invited)

    Science.gov (United States)

    Wenzel, F.

    2009-12-01

    The exponentially growing losses related to natural disasters on a global scale reflect a changing risk landscape that is characterized by the influence of climate change and a growing population, particularly in urban agglomerations and coastal zones. In consequence of these trends we witness (a) new hazards such as landslides due to dwindling permafrost, new patterns of strong precipitation and related floods, potential for tropical cyclones in the Mediterranean, sea level rise and others; (b) new risks related to large numbers of people in very dense urban areas, and risks related to the vulnerability of infrastructure such as energy supply, water supply, transportation, communication, etc. (c) extreme events with unprecedented size and implications. An appropriate answer to these challenges goes beyond classical views of risk assessment and protection. It must include an understanding of risk as changing with time so that risk assessment needs to be supplemented by risk monitoring. It requires decision making under high uncertainty. The risks (i.e. potentials for future losses) of extreme events are not only high but also very difficult to quantify, as they are characterized by high levels of uncertainty. Uncertainties relate to frequency, time of occurrence, strength and impact of extreme events but also to the coping capacities of society in response to them. The characterization, quantification, reduction in the extent possible of the uncertainties is an inherent topic of extreme event research. However, they will not disappear, so a rational approach to extreme events must include more than reducing uncertainties. It requires us to assess and rate the irreducible uncertainties, to evaluate options for mitigation under large uncertainties, and their communication to societal sectors. Thus scientist need to develop methodologies that aim at a rational approach to extreme events associated with high levels of uncertainty.

  9. Evaluation of risk impact of changes to Completion Times addressing model and parameter uncertainties

    International Nuclear Information System (INIS)

    Martorell, S.; Martón, I.; Villamizar, M.; Sánchez, A.I.; Carlos, S.

    2014-01-01

    This paper presents an approach and an example of application for the evaluation of risk impact of changes to Completion Times within the License Basis of a Nuclear Power Plant based on the use of the Probabilistic Risk Assessment addressing identification, treatment and analysis of uncertainties in an integrated manner. It allows full development of a three tired approach (Tier 1–3) following the principles of the risk-informed decision-making accounting for uncertainties as proposed by many regulators. Completion Time is the maximum outage time a safety related equipment is allowed to be down, e.g. for corrective maintenance, which is established within the Limiting Conditions for Operation included into Technical Specifications for operation of a Nuclear Power Plant. The case study focuses on a Completion Time change of the Accumulators System of a Nuclear Power Plant using a level 1 PRA. It focuses on several sources of model and parameter uncertainties. The results obtained show the risk impact of the proposed CT change including both types of epistemic uncertainties is small as compared with current safety goals of concern to Tier 1. However, what concerns to Tier 2 and 3, the results obtained show how the use of some traditional and uncertainty importance measures helps in identifying high risky configurations that should be avoided in NPP technical specifications no matter the duration of CT (Tier 2), and other configurations that could take part of a configuration risk management program (Tier 3). - Highlights: • New approach for evaluation of risk impact of changes to Completion Times. • Integrated treatment and analysis of model and parameter uncertainties. • PSA based application to support risk-informed decision-making. • Measures of importance for identification of risky configurations. • Management of important safety issues to accomplish safety goals

  10. Evaluation of energy related risk acceptance (APHA energy task force)

    International Nuclear Information System (INIS)

    Hull, A.P.

    1977-01-01

    Living in a technological society with large energy requirements involves a number of related actities with attendant health risks, both to the working and to the general public. Therefore, the formulation of some general principles for risk acceptance is necessary. In addition to maximizing benefits and minimizing risk, relevant considerations must be made about the perception of risk as voluntary or involuntary, the number of persons collectively at risk at any one occasion, and the extent to which a risk is a familiar one. With regard to a given benefit, such as a given amount of energy, comparisons of the risks of alternate modes of production may be utilized. However, cost-benefit consideration is essential to the amelioration of current or prospective risks. This is unusual, since it is based on some estimate of the monetary value per premature death averted. It is proposed that increased longevity would be a more satisfactory measure. On a societal basis, large expenditures for additional energy-related pollution control do not appear justifiable since much larger, nonenergy-related health risks are relatively underaddressed. Knowledgeable health professionals could benefit the public by imparting authoritative information in this area

  11. Developing risk management dashboards using risk and quality measures: A visual best practices approach.

    Science.gov (United States)

    Bunting, Robert F; Siegal, Dana

    2017-10-01

    Because quality measures are ubiquitous, health care risk management leaders often use them as a proxy for risk management measures. While certain quality measures adequately reflect some aspects of risk management, they are neither a perfect nor complete substitute for well-developed and comprehensive risk management measures. Using a comprehensive approach consisting of quality measures, risk measures, and measures that are less amenable to classification would be the best approach. Identifying the most powerful and informative measures, designing the most appropriate dashboards, and incorporating visual best practices are crucial steps required for evaluating the effectiveness and value of an enterprise risk management program. The authors explain the terms and concepts, review the measures available in the literature, propose new measures, discuss visual best practices, and provide sample dashboard components. © 2017 American Society for Healthcare Risk Management of the American Hospital Association.

  12. 2007 TOXICOLOGY AND RISK ASSESSMENT ...

    Science.gov (United States)

    EPA has announced The 2007 Toxicology and Risk Assessment Conference Cincinnati Marriott North, West Chester (Cincinnati), OHApril 23- 26, 2007 - Click to register!The Annual Toxicology and Risk Assessment Conference is a unique meeting where several Government Agencies come together to discuss toxicology and risk assessment issues that are not only of concern to the government, but also to a broader audience including academia and industry. The theme of this year's conference is Emerging Issues and Challenges in Risk Assessment and the preliminary agenda includes: Plenary Sessions and prominent speakers (tentative) include: Issues of Emerging Chemical ContaminantsUncertainty and Variability in Risk Assessment Use of Mechanistic data in IARC evaluationsParallel Sessions:Uncertainty and Variability in Dose-Response Assessment Recent Advances in Toxicity and Risk Assessment of RDX The Use of Epidemiologic Data for Risk Assessment Applications Cumulative Health Risk Assessment:

  13. Prevalence of 10-Year Risk of Cardiovascular Diseases and Associated Risks in Canadian Adults: The Contribution of Cardiometabolic Risk Assessment Introduction

    Directory of Open Access Journals (Sweden)

    Solmaz Setayeshgar

    2013-01-01

    Full Text Available Background. Cardiovascular disease (CVD is the leading cause of death in adult Canadians. Cardiometabolic risk (CMR derived from 10-year risk of cardiovascular diseases and metabolic syndrome (MetS needs to be evaluated in Canadian adults. Objective. To determine CMR among Canadian adults by sociodemographic and lifestyle characteristics. Subjects and Methods. Data from the Canadian Health Measures Survey (CHMS, Cycle 1, 2007–2009, was used. Framingham Risk Score (FRS was implemented to predict 10-year risk of CVD, and metabolic syndrome was identified using the most recent criteria. The 10-year risk of CVD was multiplied by 1.5 in individuals with MetS to obtain CMR. Data were weighted and bootstrapped to be able to generalize the results nationally. Results and Conclusion. CMR gave more accurate estimation of 10-year risk of CVD in Canadian adults from 30 to 74 years than using only FRS. The 10-year risk of CVD in Canadian adults significantly increased when CMR was taken into account from 8.10% to 9.86%. The CVD risk increased by increase in age, decrease in education, and decrease in physical activity and in smokers. Canadians with medium risk of CVD consumed significantly less fruit and vegetable juice compared to Canadians with low risk. No other dietary differences were found.

  14. Uncertainty Analysis and Overtopping Risk Evaluation of Maroon Dam withMonte Carlo and Latin Hypercube Methods

    Directory of Open Access Journals (Sweden)

    J. M. Vali Samani

    2016-02-01

    Full Text Available Introduction: The greatest part of constructed dams belongs to embankment dams and there are many examples of their failures throughout history. About one-third of the world’s dam failures have been caused by flood overtopping, which indicates that flood overtopping is an important factor affecting reservoir projects’ safety. Moreover, because of a poor understanding of the randomness of floods, reservoir water levels during flood seasons are often lowered artificially in order to avoid overtopping and protect the lives and property of downstream residents. So, estimation of dam overtopping risk with regard to uncertainties is more important than achieving the dam’s safety. This study presents the procedure for risk evaluation of dam overtopping due to various uncertaintiess in inflows and reservoir initial condition. Materials and Methods: This study aims to present a practical approach and compare the different uncertainty analysis methods in the evaluation of dam overtopping risk due to flood. For this purpose, Monte Carlo simulation and Latin hypercube sampling methods were used to calculate the overtopping risk, evaluate the uncertainty, and calculate the highest water level during different flood events. To assess these methods from a practical point of view, the Maroon dam was chosen for the case study. Figure. 1 indicates the work procedure, including three parts: 1 Identification and evaluation of effective factors on flood routing and dam overtopping, 2 Data collection and analysis for reservoir routing and uncertainty analysis, 3 Uncertainty and risk analysis. Figure 1- Diagram of dam overtopping risk evaluation Results and Discussion: Figure 2 shows the results of the computed overtopping risks for the Maroon Dam without considering the wind effect, for the initial water level of 504 m as an example. As it is shown in Figure. 2, the trends of the risk curves computed by the different uncertainty analysis methods are similar

  15. A Risk Metric Assessment of Scenario-Based Market Risk Measures for Volatility and Risk Estimation: Evidence from Emerging Markets

    Directory of Open Access Journals (Sweden)

    Sitima Innocent

    2015-03-01

    Full Text Available The study evaluated the sensitivity of the Value- at- Risk (VaR and Expected Shortfalls (ES with respect to portfolio allocation in emerging markets with an index portfolio of a developed market. This study utilised different models for VaR and ES techniques using various scenario-based models such as Covariance Methods, Historical Simulation and the GARCH (1, 1 for the predictive ability of these models in both relatively stable market conditions and extreme market conditions. The results showed that Expected Shortfall has less risk tolerance than VaR based on the same scenario-based market risk measures

  16. Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

    DEFF Research Database (Denmark)

    Kuchenbaecker, Karoline B; McGuffog, Lesley; Barrowdale, Daniel

    2017-01-01

    Background: Genome-wide association studies (GWAS) have identified 94 common single-nucleotide polymorphisms (SNPs) associated with breast cancer (BC) risk and 18 associated with ovarian cancer (OC) risk. Several of these are also associated with risk of BC or OC for women who carry a pathogenic ...... risk in BRCA1 and BRCA2 carriers. Incorporation of the PRS into risk prediction models has promise to better inform decisions on cancer risk management....

  17. Evaluation of Seismic Risk of Siberia Territory

    Science.gov (United States)

    Seleznev, V. S.; Soloviev, V. M.; Emanov, A. F.

    The outcomes of modern geophysical researches of the Geophysical Survey SB RAS, directed on study of geodynamic situation in large industrial and civil centers on the territory of Siberia with the purpose of an evaluation of seismic risk of territories and prediction of origin of extreme situations of natural and man-caused character, are pre- sented in the paper. First of all it concerns the testing and updating of a geoinformation system developed by Russian Emergency Ministry designed for calculations regarding the seismic hazard and response to distructive earthquakes. The GIS database contains the catalogues of earthquakes and faults, seismic zonation maps, vectorized city maps, information on industrial and housing fund, data on character of building and popula- tion in inhabited places etc. The geoinformation system allows to solve on a basis of probabilistic approaches the following problems: - estimating the earthquake impact, required forces, facilities and supplies for life-support of injured population; - deter- mining the consequences of failures on chemical and explosion-dangerous objects; - optimization problems on assurance technology of conduct of salvage operations. Using this computer program, the maps of earthquake risk have been constructed for several seismically dangerous regions of Siberia. These maps display the data on the probable amount of injured people and relative economic damage from an earthquake, which can occur in various sites of the territory according to the map of seismic zona- tion. The obtained maps have allowed determining places where the detailed seismo- logical observations should be arranged. Along with it on the territory of Siberia the wide-ranging investigations with use of new methods of evaluation of physical state of industrial and civil establishments (buildings and structures, hydroelectric power stations, bridges, dams, etc.), high-performance detailed electromagnetic researches of ground conditions of city

  18. FDA-iRISK--a comparative risk assessment system for evaluating and ranking food-hazard pairs: case studies on microbial hazards.

    Science.gov (United States)

    Chen, Yuhuan; Dennis, Sherri B; Hartnett, Emma; Paoli, Greg; Pouillot, Régis; Ruthman, Todd; Wilson, Margaret

    2013-03-01

    Stakeholders in the system of food safety, in particular federal agencies, need evidence-based, transparent, and rigorous approaches to estimate and compare the risk of foodborne illness from microbial and chemical hazards and the public health impact of interventions. FDA-iRISK (referred to here as iRISK), a Web-based quantitative risk assessment system, was developed to meet this need. The modeling tool enables users to assess, compare, and rank the risks posed by multiple food-hazard pairs at all stages of the food supply system, from primary production, through manufacturing and processing, to retail distribution and, ultimately, to the consumer. Using standard data entry templates, built-in mathematical functions, and Monte Carlo simulation techniques, iRISK integrates data and assumptions from seven components: the food, the hazard, the population of consumers, process models describing the introduction and fate of the hazard up to the point of consumption, consumption patterns, dose-response curves, and health effects. Beyond risk ranking, iRISK enables users to estimate and compare the impact of interventions and control measures on public health risk. iRISK provides estimates of the impact of proposed interventions in various ways, including changes in the mean risk of illness and burden of disease metrics, such as losses in disability-adjusted life years. Case studies for Listeria monocytogenes and Salmonella were developed to demonstrate the application of iRISK for the estimation of risks and the impact of interventions for microbial hazards. iRISK was made available to the public at http://irisk.foodrisk.org in October 2012.

  19. Hanford Site baseline risk assessment methodology

    International Nuclear Information System (INIS)

    1993-03-01

    This methodology has been developed to prepare human health and environmental evaluations of risk as part of the Comprehensive Environmental Response, Compensation, and Liability Act remedial investigations (RIs) and the Resource Conservation and Recovery Act facility investigations (FIs) performed at the Hanford Site pursuant to the Hanford Federal Facility Agreement and Consent Order referred to as the Tri-Party Agreement. Development of the methodology has been undertaken so that Hanford Site risk assessments are consistent with current regulations and guidance, while providing direction on flexible, ambiguous, or undefined aspects of the guidance. The methodology identifies Site-specific risk assessment considerations and integrates them with approaches for evaluating human and environmental risk that can be factored into the risk assessment program supporting the Hanford Site cleanup mission. Consequently, the methodology will enhance the preparation and review of individual risk assessments at the Hanford Site

  20. Clean Slate transportation and human health risk assessment

    International Nuclear Information System (INIS)

    1997-02-01

    Public concern regarding activities involving radioactive material generally focuses on the human health risk associated with exposure to ionizing radiation. This report describes the results of a risk analysis conducted to evaluate risk for excavation, handling, and transport of soil contaminated with transuranics at the Clean Slate sites. Transportation risks were estimated for public transport routes from the Tonopah Test Range (TTR) to the Envirocore disposal facility or to the Area 3 Radioactive Waste Management Site (RWMS) at the Nevada Test Site (NTS) for both radiological risk and risk due to traffic accidents. Human health risks were evaluated for occupational and radiation-related health effects to workers. This report was generated to respond to this public concern, to provide an evaluation of the risk, and to assess feasibility of transport of the contaminated soil for disposal

  1. RiskChanges Spatial Decision Support system for the analysis of changing multi-hazard risk

    Science.gov (United States)

    van Westen, Cees; Zhang, Kaixi; Bakker, Wim; Andrejchenko, Vera; Berlin, Julian; Olyazadeh, Roya; Cristal, Irina

    2015-04-01

    Within the framework of the EU FP7 Marie Curie Project CHANGES and the EU FP7 Copernicus project INCREO a spatial decision support system was developed with the aim to analyse the effect of risk reduction planning alternatives on reducing the risk now and in the future, and support decision makers in selecting the best alternatives. Central to the SDSS are the stakeholders. The envisaged users of the system are organizations involved in planning of risk reduction measures, and that have staff capable of visualizing and analyzing spatial data at a municipal scale. The SDSS should be able to function in different countries with different legal frameworks and with organizations with different mandates. These could be subdivided into Civil protection organization with the mandate to design disaster response plans, Expert organizations with the mandate to design structural risk reduction measures (e.g. dams, dikes, check-dams etc), and planning organizations with the mandate to make land development plans. The SDSS can be used in different ways: analyzing the current level of risk, analyzing the best alternatives for risk reduction, the evaluation of the consequences of possible future scenarios to the risk levels, and the evaluation how different risk reduction alternatives will lead to risk reduction under different future scenarios. The SDSS is developed based on open source software and following open standards, for code as well as for data formats and service interfaces. Code development was based upon open source software as well. The architecture of the system is modular. The various parts of the system are loosely coupled, extensible, using standards for interoperability, flexible and web-based. The Spatial Decision Support System is composed of a number of integrated components. The Risk Assessment component allows to carry out spatial risk analysis, with different degrees of complexity, ranging from simple exposure (overlay of hazard and assets maps) to

  2. Perception and evaluation of risks. Findings of the 'Baden-Wuerttemberg Risk Survey 2001'

    Energy Technology Data Exchange (ETDEWEB)

    Zwick, M.M.; Renn, O. (eds.)

    2002-05-01

    Since most of the empirical work on risk perception has been conducted in the 1970s and few studies are available that claim to span the full range of psychological, sociological and cultural variables, the Center of Technology Assessment in Stuttgart (Germany) has conducted a representative survey in the German State of Baden-Wuerttemberg on risk perception in the general population. In addition, a qualitative investigation based on a sample of 62 respondents was launched in 2001. The objective of the study was to determine the relative importance of psychometric, stigma-related, social value-related, trust-related and cultural variables in explaining risk perception and acceptance. The following report summarizes the results of these investigations. (orig.)

  3. Fuzzy Comprehensive Evaluation of Ecological Risk Based on Cloud Model: Taking Chengchao Iron Mine as Example

    Science.gov (United States)

    Ruan, Jinghua; Chen, Yong; Xiao, Xiao; Yong, Gan; Huang, Ranran; Miao, Zuohua

    2018-01-01

    Aimed at the fuzziness and randomness during the evaluation process, this paper constructed a fuzzy comprehensive evaluation method based on cloud model. The evaluation index system was established based on the inherent risk, present level and control situation, which had been proved to be able to convey the main contradictions of ecological risk in mine on the macro level, and be advantageous for comparison among mines. The comment sets and membership functions improved by cloud model could reflect the uniformity of ambiguity and randomness effectively. In addition, the concept of fuzzy entropy was introduced to further characterize the fuzziness of assessments results and the complexities of ecological problems in target mine. A practical example in Chengchao Iron Mine evidenced that, the assessments results can reflect actual situations appropriately and provide a new theoretic guidance for comprehensive ecological risk evaluation of underground iron mine.

  4. Evaluating the Risk of Re-identification of Patients from Hospital Prescription Records.

    Science.gov (United States)

    Emam, Khaled El; Dankar, Fida K; Vaillancourt, Régis; Roffey, Tyson; Lysyk, Mary

    2009-07-01

    Pharmacies often provide prescription records to private research firms, on the assumption that these records are de-identified (i.e., identifying information has been removed). However, concerns have been expressed about the potential that patients can be re-identified from such records. Recently, a large private research firm requested prescription records from the Children's Hospital of Eastern Ontario (CHEO), as part of a larger effort to develop a database of hospital prescription records across Canada. To evaluate the ability to re-identify patients from CHEO'S prescription records and to determine ways to appropriately de-identify the data if the risk was too high. The risk of re-identification was assessed for 18 months' worth of prescription data. De-identification algorithms were developed to reduce the risk to an acceptable level while maintaining the quality of the data. The probability of patients being re-identified from the original variables and data set requested by the private research firm was deemed quite high. A new de-identified record layout was developed, which had an acceptable level of re-identification risk. The new approach involved replacing the admission and discharge dates with the quarter and year of admission and the length of stay in days, reporting the patient's age in weeks, and including only the first character of the patient's postal code. Additional requirements were included in the data-sharing agreement with the private research firm (e.g., audit requirements and a protocol for notification of a breach of privacy). Without a formal analysis of the risk of re-identification, assurances of data anonymity may not be accurate. A formal risk analysis at one hospital produced a clinically relevant data set that also protects patient privacy and allows the hospital pharmacy to explicitly manage the risks of breach of patient privacy.

  5. Evaluation of fetal anthropometric measures to predict the risk for shoulder dystocia.

    Science.gov (United States)

    Burkhardt, T; Schmidt, M; Kurmanavicius, J; Zimmermann, R; Schäffer, L

    2014-01-01

    To evaluate the quality of anthropometric measures to improve the prediction of shoulder dystocia by combining different sonographic biometric parameters. This was a retrospective cohort study of 12,794 vaginal deliveries with complete sonographic biometry data obtained within 7 days before delivery. Receiver-operating characteristics (ROC) curves of various combinations of the biometric parameters, namely, biparietal diameter (BPD), occipitofrontal diameter (OFD), head circumference, abdominal diameter (AD), abdominal circumference (AC) and femur length were analyzed. The influences of independent risk factors were calculated and their combination used in a predictive model. The incidence of shoulder dystocia was 1.14%. Different combinations of sonographic parameters showed comparable ROC curves without advantage for a particular combination. The difference between AD and BPD (AD - BPD) (area under the curve (AUC) = 0.704) revealed a significant increase in risk (odds ratio (OR) 7.6 (95% CI 4.2-13.9), sensitivity 8.2%, specificity 98.8%) at a suggested cut-off ≥ 2.6 cm. However, the positive predictive value (PPV) was low (7.5%). The AC as a single parameter (AUC = 0.732) with a cut-off ≥ 35 cm performed worse (OR 4.6 (95% CI 3.3-6.5), PPV 2.6%). BPD/OFD (a surrogate for fetal cranial shape) was not significantly different between those with and those without shoulder dystocia. The combination of estimated fetal weight, maternal diabetes, gender and AD - BPD provided a reasonable estimate of the individual risk. Sonographic fetal anthropometric measures appear not to be a useful tool to screen for the risk of shoulder dystocia due to a low PPV. However, AD - BPD appears to be a relevant risk factor. While risk stratification including different known risk factors may aid in counseling, shoulder dystocia cannot effectively be predicted. Copyright © 2013 ISUOG. Published by John Wiley & Sons Ltd.

  6. RADON AND CARCINOGENIC RISK IN MOSCOW

    Directory of Open Access Journals (Sweden)

    S. M. Golovanev

    2015-01-01

    Full Text Available Objective: comparative evaluation of carcinogenic risk inMoscowfrom radon in indoor and atmospheric pollutants.Materials and methods: the lung cancer incidence in Moscow; radiation-hygienic passport of the territory; .U.S. EPA estimated average age at all and radon induced deaths, years of life lost; Report of UNSCEAR 2006 and WHO handbook on indoor radon, 2009. Trend analysis of incidence; evaluation of the excess relative risk; assessment of ratio radon-induced population risk and published values оf total population carcinogenic risk from chemical carcinogens.Results: it is shown that the 304 cases of lung cancer per year (1. 85 10-3 on average from 2006 to 2011 (21280diseases for 70 years in addition to background level induced by radon; the differences in average trends of all lungcancer incidence in the districts can exceed 25%.Conclusion. The potential of risk reduction by measures of mitigation radon concentration exceeds 5 times the cost efficiency to reduce emissions from vehicles and can reduce cancer incidence, on average 236 cases per year; population risk 16520 cases over 70 years or save not less than 2832 person-years of life per year. The annual effect of reducing losses from not-survival of 12 years as a result of radon-induced lung cancer deaths exceeds 14160000 dollars. The evaluating of the carcinogenic risk from radon in accordance with the definition of population risk increases the predictive evaluation of the effectiveness of preventive measures more than twice.

  7. Application of TRiMiCri for the evaluation of risk based microbiological criteria for Campylobacter on broiler meat

    DEFF Research Database (Denmark)

    Seliwiorstow, Tomasz; Uyttendaele, Mieke; De Zutter, Lieven

    2016-01-01

    A potential solution for the reduction of consumer exposure to Campylobacter is establishing a microbiological criterion (MC) for Campylobacter on broiler meat. In the present study the freely available software tool TRiMiCri was applied to evaluate risk-based microbiological criteria by two appr...... of microbiological criteria for Campylobacter in the EU is discussed. TRiMiCri provides user friendly software to evaluate the available data and can help risk managers in establishing risk based microbiological criteria for Campylobacter in broiler meat.......A potential solution for the reduction of consumer exposure to Campylobacter is establishing a microbiological criterion (MC) for Campylobacter on broiler meat. In the present study the freely available software tool TRiMiCri was applied to evaluate risk-based microbiological criteria by two...

  8. Ecological risk of anthropogenic pollutants to reptiles: Evaluating assumptions of sensitivity and exposure

    International Nuclear Information System (INIS)

    Weir, Scott M.; Suski, Jamie G.; Salice, Christopher J.

    2010-01-01

    A large data gap for reptile ecotoxicology still persists; therefore, ecological risk assessments of reptiles usually incorporate the use of surrogate species. This necessitates that (1) the surrogate is at least as sensitive as the target taxon and/or (2) exposures to the surrogate are greater than that of the target taxon. We evaluated these assumptions for the use of birds as surrogates for reptiles. Based on a survey of the literature, birds were more sensitive than reptiles in less than 1/4 of the chemicals investigated. Dietary and dermal exposure modeling indicated that exposure to reptiles was relatively high, particularly when the dermal route was considered. We conclude that caution is warranted in the use of avian receptors as surrogates for reptiles in ecological risk assessment and emphasize the need to better understand the magnitude and mechanism of contaminant exposure in reptiles to improve exposure and risk estimation. - Avian receptors are not universally appropriate surrogates for reptiles in ecological risk assessment.

  9. Ecological risk of anthropogenic pollutants to reptiles: Evaluating assumptions of sensitivity and exposure

    Energy Technology Data Exchange (ETDEWEB)

    Weir, Scott M., E-mail: scott.weir@ttu.ed [Texas Tech University, Institute of Environmental and Human Health, Department of Environmental Toxicology, Box 41163, Lubbock, TX (United States); Suski, Jamie G., E-mail: jamie.suski@ttu.ed [Texas Tech University, Department of Biological Sciences, Box 43131, Lubbock, TX (United States); Salice, Christopher J., E-mail: chris.salice@ttu.ed [Texas Tech University, Institute of Environmental and Human Health, Department of Environmental Toxicology, Box 41163, Lubbock, TX (United States)

    2010-12-15

    A large data gap for reptile ecotoxicology still persists; therefore, ecological risk assessments of reptiles usually incorporate the use of surrogate species. This necessitates that (1) the surrogate is at least as sensitive as the target taxon and/or (2) exposures to the surrogate are greater than that of the target taxon. We evaluated these assumptions for the use of birds as surrogates for reptiles. Based on a survey of the literature, birds were more sensitive than reptiles in less than 1/4 of the chemicals investigated. Dietary and dermal exposure modeling indicated that exposure to reptiles was relatively high, particularly when the dermal route was considered. We conclude that caution is warranted in the use of avian receptors as surrogates for reptiles in ecological risk assessment and emphasize the need to better understand the magnitude and mechanism of contaminant exposure in reptiles to improve exposure and risk estimation. - Avian receptors are not universally appropriate surrogates for reptiles in ecological risk assessment.

  10. The NASA Continuous Risk Management Process

    Science.gov (United States)

    Pokorny, Frank M.

    2004-01-01

    As an intern this summer in the GRC Risk Management Office, I have become familiar with the NASA Continuous Risk Management Process. In this process, risk is considered in terms of the probability that an undesired event will occur and the impact of the event, should it occur (ref., NASA-NPG: 7120.5). Risk management belongs in every part of every project and should be ongoing from start to finish. Another key point is that a risk is not a problem until it has happened. With that in mind, there is a six step cycle for continuous risk management that prevents risks from becoming problems. The steps are: identify, analyze, plan, track, control, and communicate & document. Incorporated in the first step are several methods to identify risks such as brainstorming and using lessons learned. Once a risk is identified, a risk statement is made on a risk information sheet consisting of a single condition and one or more consequences. There can also be a context section where the risk is explained in more detail. Additionally there are three main goals of analyzing a risk, which are evaluate, classify, and prioritize. Here is where a value is given to the attributes of a risk &e., probability, impact, and timeframe) based on a multi-level classification system (e.g., low, medium, high). It is important to keep in mind that the definitions of these levels are probably different for each project. Furthermore the risks can be combined into groups. Then, the risks are prioritized to see what risk is necessary to mitigate first. After the risks are analyzed, a plan is made to mitigate as many risks as feasible. Each risk should be assigned to someone in the project with knowledge in the area of the risk. Then the possible approaches to choose from are: research, accept, watch, or mitigate. Next, all risks, mitigated or not, are tracked either individually or in groups. As the plan is executed, risks are re-evaluated, and the attribute values are adjusted as necessary. Metrics

  11. Optimal fuel-mix in CHP plants under a stochastic permit price. Risk-neutrality versus risk-aversion

    Energy Technology Data Exchange (ETDEWEB)

    Lappi, Pauli; Ollikka, Kimmo; Ollikainen, Markku [Department of Economics and Management, P.O. Box 27, University of Helsinki, FIN-00014 Helsinki (Finland)

    2010-02-15

    This paper studies the optimal fuel-mix of a CHP producer under emission permit price risk. The producer's multi-fuel plant uses two CO{sub 2}-intensive fuels and one clean fuel. Using a mean-variance framework we develop three models. The models are divided into spot-models (risk neutral and risk averse cases) and a forward-model (risk averse case). We derive the effects of price risk on optimal fuel use. An increase in price risk can in fact increase the use of CO{sub 2}-intensive fuel in the spot-model. In the forward-model, the production and financial decisions are separate. We also evaluate the risk-bearing behavior of seven Finnish CHP producers. We found that risk-neutrality describes behavior better than risk-aversion. (author)

  12. Optimal fuel-mix in CHP plants under a stochastic permit price: Risk-neutrality versus risk-aversion

    Energy Technology Data Exchange (ETDEWEB)

    Lappi, Pauli, E-mail: pauli.lappi@helsinki.f [Department of Economics and Management, P.O. Box 27, University of Helsinki, FIN-00014 Helsinki (Finland); Ollikka, Kimmo, E-mail: kimmo.ollikka@helsinki.f [Department of Economics and Management, P.O. Box 27, University of Helsinki, FIN-00014 Helsinki (Finland); Ollikainen, Markku, E-mail: markku.ollikainen@helsinki.f [Department of Economics and Management, P.O. Box 27, University of Helsinki, FIN-00014 Helsinki (Finland)

    2010-02-15

    This paper studies the optimal fuel-mix of a CHP producer under emission permit price risk. The producer's multi-fuel plant uses two CO{sub 2}-intensive fuels and one clean fuel. Using a mean-variance framework we develop three models. The models are divided into spot-models (risk neutral and risk averse cases) and a forward-model (risk averse case). We derive the effects of price risk on optimal fuel use. An increase in price risk can in fact increase the use of CO{sub 2}-intensive fuel in the spot-model. In the forward-model, the production and financial decisions are separate. We also evaluate the risk-bearing behavior of seven Finnish CHP producers. We found that risk-neutrality describes behavior better than risk-aversion.

  13. Cyber Security Risk Evaluation of a Nuclear I&C Using BN and ET

    OpenAIRE

    Jinsoo Shin; Hanseong Son; Gyunyoung Heo

    2017-01-01

    Cyber security is an important issue in the field of nuclear engineering because nuclear facilities use digital equipment and digital systems that can lead to serious hazards in the event of an accident. Regulatory agencies worldwide have announced guidelines for cyber security related to nuclear issues, including U.S. NRC Regulatory Guide 5.71. It is important to evaluate cyber security risk in accordance with these regulatory guides. In this study, we propose a cyber security risk evaluatio...

  14. History-Dependent Risk Attitude, Second Version

    OpenAIRE

    David Dillenberger; Kareen Rozen

    2011-01-01

    We propose a model of history-dependent risk attitude, allowing a decision maker’s risk attitude to be affected by his history of disappointments and elations. The decision maker recursively evaluates compound risks, classifying realizations as disappointing or elating using a threshold rule. We establish equivalence between the model and two cognitive biases: risk attitudes are reinforced by experiences (one is more risk averse after disappointment than after elation) and there is a primacy ...

  15. Model-based mitigation of availability risks

    NARCIS (Netherlands)

    Zambon, E.; Bolzoni, D.; Etalle, S.; Salvato, M.

    2007-01-01

    The assessment and mitigation of risks related to the availability of the IT infrastructure is becoming increasingly important in modern organizations. Unfortunately, present standards for risk assessment and mitigation show limitations when evaluating and mitigating availability risks. This is due

  16. Model-Based Mitigation of Availability Risks

    NARCIS (Netherlands)

    Zambon, Emmanuele; Bolzoni, D.; Etalle, Sandro; Salvato, Marco

    2007-01-01

    The assessment and mitigation of risks related to the availability of the IT infrastructure is becoming increasingly important in modern organizations. Unfortunately, present standards for Risk Assessment and Mitigation show limitations when evaluating and mitigating availability risks. This is due

  17. Application of probabilistic risk assessment: Evaluating remedial alternatives at the Portland Harbor Superfund Site, Portland, Oregon, USA.

    Science.gov (United States)

    Ruffle, Betsy; Henderson, James; Murphy-Hagan, Clare; Kirkwood, Gemma; Wolf, Frederick; Edwards, Deborah A

    2018-01-01

    A probabilistic risk assessment (PRA) was performed to evaluate the range of potential baseline and postremedy health risks to fish consumers at the Portland Harbor Superfund Site (the "Site"). The analysis focused on risks of consuming fish resident to the Site containing polychlorinated biphenyls (PCBs), given that this exposure scenario and contaminant are the primary basis for US Environmental Protection Agency's (USEPA's) selected remedy per the January 2017 Record of Decision (ROD). The PRA used probability distributions fit to the same data sets used in the deterministic baseline human health risk assessment (BHHRA) as well as recent sediment and fish tissue data to evaluate the range and likelihood of current baseline cancer risks and noncancer hazards for anglers. Areas of elevated PCBs in sediment were identified on the basis of a geospatial evaluation of the surface sediment data, and the ranges of risks and hazards associated with pre- and postremedy conditions were calculated. The analysis showed that less active remediation (targeted to areas with the highest concentrations) compared to the remedial alternative selected by USEPA in the ROD can achieve USEPA's interim risk management benchmarks (cancer risk of 10 -4 and noncancer hazard index [HI] of 10) immediately postremediation for the vast majority of subsistence anglers that consume smallmouth bass (SMB) fillet tissue. In addition, the same targeted remedy achieves USEPA's long-term benchmarks (10 -5 and HI of 1) for the majority of recreational anglers. Additional sediment remediation would result in negligible additional risk reduction due to the influence of background. The PRA approach applied here provides a simple but adaptive framework for analysis of risks and remedial options focused on variability in exposures. It can be updated and refined with new data to evaluate and reduce uncertainty, improve understanding of the Site and target populations, and foster informed remedial decision

  18. Risk assessment of the oriental chestnut gall wasp, Dryocosmus kuriphilus for the EU territory and identification and evaluation of risk management options

    DEFF Research Database (Denmark)

    Baker, R.; Candresse, T.; Dormannsné Simon, E.

    2010-01-01

    in its assessment that a) Castanea plants for intended planting represent the main pathway for entry of D. kuriphilus to the EU; b) D. kuriphilus has a very high potential for establishment in the EU and the climate is suitable wherever Castanea sativa is grown in southern, central and western Europe; c......The Panel on Plant Health was requested by the European Commission to deliver a scientific opinion on the risk posed by the oriental chestnut gall wasp, Dryocosmus kuriphilus to the EU territory and to identify and evaluate risk management options. Additional analyses were conducted by the Panel...... to a) determine the distribution of the endangered area within the EU territory; b) investigate the pattern and rate of pest diffusion and c) consider the environmental risk of introduction of the biological control agent Torymus sinensis identified as a potential management option. The Panel concluded...

  19. A guide to understanding and implementing risk evaluation and mitigation strategies in organ transplantation.

    Science.gov (United States)

    Gabardi, Steven; Tichy, Eric M

    2013-03-01

    To review the components of the Congressional mandate for risk evaluation and mitigation strategies (REMS) managed by the Food and Drug Administration and assess their impact on health care providers practicing within the organ transplant arena. A non-date-limited search of MEDLINE and EMBASE (January 2007-June 2012) was conducted by using the following search terms: risk evaluation and mitigation strategies, REMS, and organ transplant, including a query of the individual organs. Information from the Federal Register and the Food and Drug Administration was also evaluated. REMS are strategies implemented to manage known or potential risks associated with medications and to ensure ongoing pharmacovigilance throughout the life of a pharmaceutical product. Elements of REMS programs may consist of 3 levels: a medication guide, communication plan, and elements to assure safe use. A medication guide is used to help prevent serious adverse events, aid in patients' decision making, and enhance medication adherence. Communication plans help educate health care providers and encourage adherence with REMS. The elements to assure safe use is a restrictive process implemented when it is deemed necessary to ensure safe access for patients to products with known serious risks. In transplant medicine, REMS currently exist for belatacept (medication guide and communication plan) and the mycophenolic acid derivatives (medication guide and elements to assure safe use). REMS are another step in the evolution of the development and marketing of pharmaceutical agents. Use of REMS in solid-organ transplant is becoming common. Transplant clinicians must provide required patient education and become involved with other aspects of REMS implementation to reduce the serious risks of pharmaceuticals and to improve patients' outcomes.

  20. Risk perception of tsunami in the community of Arauco, Chile - a contribution of risk perception to disaster risk management at local level

    Science.gov (United States)

    Kubisch, M. Sc. Susanne; Edilia Jaque Castillo, Dra.; Braun, JProf. Andreas Ch., ,, Dr.

    2017-04-01

    The research was carried out in the city center of the coastal community of Arauco, Central Chile. The community of Arauco was one of the most affected communities of the tsunami in Chile, the 27th of February 2010. For the data evaluation, the affected inhabitants of the community have been surveyed via standardized questionnaires. Furthermore experts of different fields, amongst others, Disaster Risk Management (DRM), risk education, urban and regional planning, as well as geology have been consulted in form of expert interviews. The results revealed a high risk perception part of the affected community and a weakness of DRM especially at local level, which opens a gap between the evaluation and treatment of risk by experts and risk perception of the affected community. The risk perception of the affected community, here, is predominantly determined by ecological vulnerability, expressed in direct and indirect experience of a tsunami and by institutional vulnerability, expressed among others by a weakness of DRM at local level and a mistrust in responsible institutions for DRM. Due to the institutional vulnerability and the mistrust in responsible institutions we recommend a Community Based Approach (CBA) to strengthen DRM at local level and to take advantage of the high risk perception and knowledge of the affected community. Involving the community in DRM, we assume to close the gap between risk evaluation of experts and risk perception of the inhabitants and to come up with the unique necessities and conditions at local level. Especially in centralized countries, DRM is less effective, because at the one hand, decisions are made distant from the affected communities, so that measures often do not come up with the unique conditions and necessities at local level, and on the other hand measures often do not find acceptance by the affected community. Furthermore centralized DRM is often not effective and quick in response in case of emergency. Another obstacle

  1. Cyber security risk evaluation of a nuclear I and C using BN and ET

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Jin Soo; Heo, Gyun Young [Dept. of Nuclear Engineering, Kyung Hee University, Yongin (Korea, Republic of); Son, Han Seong [Computer and Game Science, Joongbu University, Geumsan (Korea, Republic of)

    2017-04-15

    Cyber security is an important issue in the field of nuclear engineering because nuclear facilities use digital equipment and digital systems that can lead to serious hazards in the event of an accident. Regulatory agencies worldwide have announced guidelines for cyber security related to nuclear issues, including U.S. NRC Regulatory Guide 5.71. It is important to evaluate cyber security risk in accordance with these regulatory guides. In this study, we propose a cyber security risk evaluation model for nuclear instrumentation and control systems using a Bayesian network and event trees. As it is difficult to perform penetration tests on the systems, the evaluation model can inform research on cyber threats to cyber security systems for nuclear facilities through the use of prior and posterior information and backpropagation calculations. Furthermore, we suggest a methodology for the application of analytical results from the Bayesian network model to an event tree model, which is a probabilistic safety assessment method. The proposed method will provide insight into safety and cyber security risks.

  2. Cyber security risk evaluation of a nuclear I and C using BN and ET

    International Nuclear Information System (INIS)

    Shin, Jin Soo; Heo, Gyun Young; Son, Han Seong

    2017-01-01

    Cyber security is an important issue in the field of nuclear engineering because nuclear facilities use digital equipment and digital systems that can lead to serious hazards in the event of an accident. Regulatory agencies worldwide have announced guidelines for cyber security related to nuclear issues, including U.S. NRC Regulatory Guide 5.71. It is important to evaluate cyber security risk in accordance with these regulatory guides. In this study, we propose a cyber security risk evaluation model for nuclear instrumentation and control systems using a Bayesian network and event trees. As it is difficult to perform penetration tests on the systems, the evaluation model can inform research on cyber threats to cyber security systems for nuclear facilities through the use of prior and posterior information and backpropagation calculations. Furthermore, we suggest a methodology for the application of analytical results from the Bayesian network model to an event tree model, which is a probabilistic safety assessment method. The proposed method will provide insight into safety and cyber security risks

  3. Risk of energy production

    International Nuclear Information System (INIS)

    Inhaber, Herbert.

    1978-03-01

    Every human activity involves risk of accident or disease. Generation of energy is no exception. Although such risk has been considered for conventional systems (coal, oil and nuclear), a similar analysis for the so-called alternative or non-conventional systems (solar, wind, ocean thermal and methanol) has been lacking. This paper presents an evaluation of the risk, both occupational and to the public, of non-conventional energy systems. They are considered both in absolute terms and in relation to conventional systems. The risk of most non-conventional systems, per unit of energy output, is comparable to, and in some cases much higher than, the risk from coal and oil. This conclusion holds whether we consider deaths or injuries. Nuclear power and natural gas had the lowest overall risk of the ten technologies considered. Ocean thermal energy ranked third. The surprising result is that the other seven technologies considered were found to be up to 100 times less safe. The total risk is calculated by considering six components: material acquisition and construction, emissions caused by material production, operation and maintenance, energy back-up, energy storage, and transportation. In this way the risk of widely different systems can be fairly assessed. This methodology of 'risk accounting' will not tell us which energy technology to use. However, it can be employed to inform society of the risk inherent in competing energy systems. (author)

  4. Prospective evaluation of stress myocardial perfusion imaging for pre-operative cardiac risk assessment

    International Nuclear Information System (INIS)

    Byrne, A.J.; Rowe, C.C.; Flannery, G.

    2002-01-01

    Full text: A prospective evaluation of patients who underwent stress myocardial perfusion imaging (MPI) to assess preoperative cardiac risk was undertaken. At the time of the scan patients were classified into 4 Clinical Risk groups (CR) based on known clinical data. On completion of the scan, the patient was then categorised into 4 Scan based Risk groups (SR), incorporating size of perfusion deficit, single versus multi-vessel disease and ejection fraction. Surgery at Austin and Repatriation Medical Centre within 6 months of scan and complications were identified using the hospital medical database. Major early cardiac events coded were death (cardiac related), myocardial infarction, unstable angina, acute pulmonary oedema, cardiac arrest, and urgent revascularisation. 208 patients have reached 6 months post-MPI scan. Of these 119 (57%) were identified as having surgery. Of the Scan Risk groups, 63% of normal, 57% of increased, and 47% of high and very high groups have had surgery. An abnormal scan is associated with a three-fold risk of cardiac complication (3.5% vs 11.3%). This is lower than most previous reports and may be due to higher representation of low risk surgical procedures (14% in this series), improved peri-operative care and/or the test result influence on management (suggested by decreasing surgical rate as SR estimate rose). Copyright (2002) The Australian and New Zealand Society of Nuclear Medicine Inc

  5. Risk Control of Offshore Installations. A Framework for the Establishment of Risk Indicators

    Energy Technology Data Exchange (ETDEWEB)

    Oeien, Knut

    2001-07-01

    Currently quantitative risk assessments are carried out to analyze the risk level of offshore installations and to evaluate whether or not the risk level is acceptable. By way of the quantitative risk analysis the risk status of a given installation is obtained. However, the risk status is obtained so infrequently that it is inadequate for risk control. It can be compared to economic control having the economic status presented about each fifth year, which is obviously inadequate. It is important to know the risk status because this may provide an early warning about the need for remedial actions. Without frequent information about the risk status, control of risk cannot be claimed. The main objective of this thesis has been the development of a framework for the establishment of risk indicators. These risk indicators provide a status of the risk level through measuring of changes in technical, operational and organizational factors important to risk, and is thus a means to control risk during operation of offshore petroleum installations. The framework consists of a technical methodology using the quantitative risk assessment as a basis, an organizational model, and an organizational quantification methodology. Technical risk indicators are established from the technical methodology covering the risk factors explicitly included in the quantitative risk assessment. Organizational risk indicators measure changes in the organizational risk factors included in the organizational model, but not included in the quantitative risk assessment. The organizational model is an extension to the risk model in the quantitative risk assessment. The organizational quantification methodology calculates the effect of the changes measured by the organizational risk indicators. The organizational model may also be applied as a qualitative tool for root cause analysis of incidents (process leaks). Other results are an intermediate-level expert judgment procedure applicable for

  6. Java project on periodontal diseases. The natural development of periodontitis: risk factors, risk predictors and risk determinants : risk factors, risk predictors and risk determinants

    NARCIS (Netherlands)

    Van der Velden, U.; Abbas, F.; Armand, S.; Loos, B. G.; Timmerman, M. F.; Van der Weijden, G. A.; Van Winkelhoff, A. J.; Winkel, E. G.

    Objective: To identify risk factors, risk predictors and risk determinants for onset and progression of periodontitis. Material and Methods: For this longitudinal, prospective study all subjects in the age range 15-25 years living in a village of approximately 2000 inhabitants at a tea estate on

  7. Evaluation Logic of Main Control Board Fire Risk

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Dae Il; Kim, Kilyoo; Lim, Ho Gon [KAERI, Daejeon (Korea, Republic of)

    2015-05-15

    The main control board (MCB) is defined as the collection of control panels inside the main control room (MCR) of a nuclear power plant (NPP). As the MCB has the control and instrumentation circuits of redundant trains for almost all plant systems, small fires within the control panels may be detrimental to the safe shutdown capability. A big fire affecting many panels in the MCB can cause a forced MCR abandonment of the operators as well as function failures or spurious operations of the control and instrumentation-related components. If the MCR cannot be habitable, a safe shutdown from outside the MCR can be achieved and maintained at an alternate shutdown panel electrically and physically independent from the MCR. Because the MCB consist of many electrical panels, it may have internal barriers between them to prevent a fire from spreading from its origin to neighboring locations. However, most MCBs of domestic NPPs do not have internal barriers within them. If the MCB cabinets are not separated by a double wall with an air gap, the fire propagation of an MCB panel fire cannot be ruled out. Recently, Joglar et al. proposed a new evaluation logic for the MCB panel fires and mentioned that an MCB fire can be divided into propagation and non-propagating fires for abandonment and non-abandonment fire scenarios. However, they did not present the details on the fire modeling approaches and probability formulas for the fire scenarios. In this paper, a decision tree for evaluating the risk of an MCB fire is proposed to systematically determine the fire scenarios in terms of the fire modeling approaches. This paper proposed a decision tree for evaluating the risk of an MCB fire to systematically determine the fire scenarios in terms of fire modeling approaches.

  8. Flood risk management in Flanders: from flood risk objectives to appropriate measures through state assessment

    Directory of Open Access Journals (Sweden)

    Verbeke Sven

    2016-01-01

    Full Text Available In compliance with the EU Flood Directive to reduce flood risk, flood risk management objectives are indispensable for the delineation of necessary measures. In Flanders, flood risk management objectives are part of the environmental objectives which are judicially integrated by the Decree on Integrated Water Policy. Appropriate objectives were derived by supporting studies and extensive consultation on a local, regional and policy level. Under a general flood risk objective sub-objectives are formulated for different aspects: water management and safety, shipping, ecology, and water supply. By developing a risk matrix, it is possible to assess the current state of flood risk and to judge where action is needed to decrease the risk. Three different states of flood risk are distinguished: a acceptable risk, where no action is needed, b intermediate risk where the risk should be reduced by cost efficient actions, and c unacceptable risk, where action is necessary. For each particular aspect, the severity of the consequences of flooding is assessed by quantifiable indicators, such as economic risk, people at risk and ecological flood tolerance. The framework also allows evaluating the effects of the implemented measures and the autonomous development such as climate change and land use change. This approach gives a quantifiable assessment of state, and enables a prioritization of flood risk measures for the reduction of flood risk in a cost efficient and sustainable way.

  9. Risk management, financial evaluation and funding for wastewater and stormwater reuse projects.

    Science.gov (United States)

    Furlong, Casey; De Silva, Saman; Gan, Kein; Guthrie, Lachlan; Considine, Robert

    2017-04-15

    This paper has considered risk management, financial evaluation and funding in seven Australian wastewater and stormwater reuse projects. From the investigated case studies it can be seen that responsible parties have generally been well equipped to identify potential risks. In relation to financial evaluation methods some serious discrepancies, such as time periods for analysis, and how stormwater benefits are valued, have been identified. Most of the projects have required external, often National Government, funding to proceed. As National funding is likely to become less common in the future, future reuse projects may need to be funded internally by the water industry. In order to enable this the authors propose that the industry requires (1) a standard project evaluation process, and (2) an infrastructure funders' forum (or committee) with representation from both utilities and regulators, in order to compare and prioritise future reuse projects against each other. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. 76 FR 57767 - Proposed Generic Communication; Draft NRC Generic Letter 2011-XX: Seismic Risk Evaluations for...

    Science.gov (United States)

    2011-09-16

    ... NUCLEAR REGULATORY COMMISSION [NRC-2011-0204] Proposed Generic Communication; Draft NRC Generic Letter 2011-XX: Seismic Risk Evaluations for Operating Reactors AGENCY: Nuclear Regulatory Commission... FR 54507), that requested public comment on Draft NRC Generic Letter 2011- XX: Seismic Risk...

  11. Cardiovascular risk prediction in the Netherlands

    NARCIS (Netherlands)

    Dis, van S.J.

    2011-01-01

    Background: In clinical practice, Systematic COronary Risk Evaluation (SCORE) risk prediction functions and charts are used to identify persons at high risk for cardiovascular diseases (CVD), who are considered eligible for drug treatment of elevated blood pressure and serum cholesterol. These

  12. Critical infrastructure cyber-security risk management

    OpenAIRE

    Spyridopoulos, T.; Maraslis, K.; Tryfonas, T.; Oikonomou, G.

    2017-01-01

    Traditional IT cyber-security risk management methods are based on the evaluation of risks calculated as the likelihood of cyber-security incidents occurring. However, these probabilities are usually estimations or guesses based on past experience and incomplete data. Incorrect estimations can lead to errors in the evaluation of risks that can ultimately affect the protection of the system. This issue is also transferred to methods used in Industrial Control Systems (ICSs), as they are mainly...

  13. Drug utilization research and risk management

    NARCIS (Netherlands)

    Mazzaglia, Giampiero; Mol, Peter G. M.; Elseviers, Monique; Wettermark, Björn; Almarsdóttir, Anna Birna; Andersen, Morten; Benko, Ria; Bennie, Marion; Eriksson, Irene; Godman, Brian; Krska, Janet; Poluzzi, Elisabetta; Taxis, Katja; Vlahovic-Palcevski, Vera; Stichele, Robert Vander

    2016-01-01

    Good risk management requires continuous evaluation and improvement of planned activities. The evaluation impact of risk management activities requires robust study designs and carefully selected outcome measures. Key learnings and caveats from drug utilization research should be applied to the

  14. Discussion of some issues in risk study

    International Nuclear Information System (INIS)

    Qu Jingyuan; Liu Yuanzhong

    1998-01-01

    The concept of risk, the methods for assessing risk and the acceptability of risk are discussed. The emphasis was laid on the three components for complete description of a risk: scenario, probability and consequence of an event. The disadvantages of the concept and presentation of risk used in some risk analysis were pointed out. The paper emphasized that it is necessary to explicitly consider the multi-dimensionality of risk in the assessment and management of risk. Several important factors influencing the acceptability of risk and the methodology for evaluating the acceptability of risk were also described

  15. Environmental and social risk evaluation of overseas investment under the China-Pakistan Economic Corridor.

    Science.gov (United States)

    Zhang, Ruilian; Andam, Francis; Shi, Guoqing

    2017-06-01

    Along with the further implementation of the "One Belt, One Road" initiative and the promotion of the China-Pakistan Economic Corridor (CPEC), the construction of the CPEC will likely face challenges owing to differences between China and Pakistan in politics, economics, culture, religion, language, customs, environmental management systems, environmental protection laws, social management systems, and social management regulations. To address potential environmental and social risks associated with Chinese enterprises as they invest in the CPEC region, this paper examines previous studies addressing topics such as the environmental and social safeguards of international institutions and Pakistan's domestic environmental and social management requirements. We then systematically identify the environmental and social risk factors involved in CPEC construction, which cover risks regarding water, air, soil, noise, biodiversity, politics, economics, culture, technology, and individuals. By establishing and calculating these risks and using a multi-fuzzy comprehensive evaluation model, we found that noise and individual risks belong to a medium risk category, while others belong to a higher risk category. In view of these risks, the Chinese government must create a friendly and peaceful environment for Chinese enterprises to invest in the CPEC region, and Chinese enterprises must adopt a development strategy of strength and capacity building and establish enterprises capable of addressing environmental and social issues during the investment process. All stakeholders must understand that if no determined and diligent steps are taken, CPEC construction might be doomed for failure from the start.

  16. Evaluating the risk-reduction benefits of wind energy

    Energy Technology Data Exchange (ETDEWEB)

    Brower, M.C.; Bell, K.; Spinney, P. [and others

    1997-05-01

    The question of uncertainty and risk in electric utility resource planning has received considerable attention in recent years. During the 1980s, many utilities suffered financial losses because of unexpectedly high plant construction costs and low growth in electricity demand. In addition, the introduction of competition to the electric industry is creating new risks for power companies. No longer will utilities be able to count on regulatory protections and a base of captive consumers to provide a stable market and adequate return on their investments. Alternative risk management strategies will have to be considered instead. One approach to managing risk is for a utility company to invest in diverse power sources such as wind power plants. Since wind plants consume no fuel, can be built in relatively small increments with short construction lead times, and generate no pollutants, it is often said that they offer significant protection from risks associated with conventional fossil-fuel power plants. So far there have been few efforts to quantify these benefits, however. The study compares the costs and risks of two competing resource options, a gas-fired combined cycle plant and a wind plant, both utility-owned, through decision analysis. The case study utility is Texas Utilities Electric, a very large investor-owned company serving an area with substantial, high-quality wind resources. The authors chose a specific moment in the future - the year 2003 - when the utility currently plans to build a large fossil-fueled power plant, and examined the implications for the utility`s expected revenues, costs, and profits if a wind plant were to be built instead.

  17. [Evaluation of occupational risk factors, nutritional habits and nutritional status in industrial workers].

    Science.gov (United States)

    Domagała-Dobrzycka, M

    2000-01-01

    The objective of this study was to examine the relationship between selected risk factors at the workplace and health indices in relation to nutritional habits and nutritional status in industrial workers. Exposure to physical and chemical risk factors and their impact on health in the province of Szczecin and in Poland was evaluated basing on data published in the Yearbooks of the Province of Szczecin, the Central Statistics Bureau (GUS) and Regional Inspectorate of Labor (OIP) in Szczecin. A random selection of plants in Szczecin was done and workplaces with chemical and physical risk levels exceeding the highest acceptable values were identified. Measurements of concentrations of chemicals and intensity of physical factors were performed by Work Environment Research Laboratories of the plants and by the laboratory of the Sanitary and Epidemiological Center in Szczecin. Eighty-eight men exposed to occupational risk factors were randomly selected. The mean period of exposure in that group was approximately ten years. The control group was composed of male workers (n = 83) not exposed to any of the risk factors in question (Tab. 3). Nutritional habits and nutritional status were studied during summer/autumn and winter/spring periods. Dietary survey consisted of the last 24-hour nutrient intake questionnaire. Nutritional status evaluation was based on body mass index (BMI) values and results of the following laboratory tests: blood cell count, levels of total protein, prealbumin, retinol binding protein (RBP), magnesium, inorganic phosphorus, and ascorbic acid. The following results were obtained: 1. Physical factors constituted the most frequent source of occupational risk in the province of Szczecin and in Poland in 1990-1994 (Tab. 1); 2. The incidence of occupational risk and occupational disease morbidity rates in 1990-1994 were lower for the province of Szczecin than the average for Poland; 3. The rate of fatal accidents at work in 1982-1994 was higher for the

  18. Risk factors for stress fractures.

    Science.gov (United States)

    Bennell, K; Matheson, G; Meeuwisse, W; Brukner, P

    1999-08-01

    Preventing stress fractures requires knowledge of the risk factors that predispose to this injury. The aetiology of stress fractures is multifactorial, but methodological limitations and expediency often lead to research study designs that evaluate individual risk factors. Intrinsic risk factors include mechanical factors such as bone density, skeletal alignment and body size and composition, physiological factors such as bone turnover rate, flexibility, and muscular strength and endurance, as well as hormonal and nutritional factors. Extrinsic risk factors include mechanical factors such as surface, footwear and external loading as well as physical training parameters. Psychological traits may also play a role in increasing stress fracture risk. Equally important to these types of analyses of individual risk factors is the integration of information to produce a composite picture of risk. The purpose of this paper is to critically appraise the existing literature by evaluating study design and quality, in order to provide a current synopsis of the known scientific information related to stress fracture risk factors. The literature is not fully complete with well conducted studies on this topic, but a great deal of information has accumulated over the past 20 years. Although stress fractures result from repeated loading, the exact contribution of training factors (volume, intensity, surface) has not been clearly established. From what we do know, menstrual disturbances, caloric restriction, lower bone density, muscle weakness and leg length differences are risk factors for stress fracture. Other time-honoured risk factors such as lower extremity alignment have not been shown to be causative even though anecdotal evidence indicates they are likely to play an important role in stress fracture pathogenesis.

  19. Evaluation of unit risk factors in support of the Hanford Remedial Action Environmental Impact Statement

    International Nuclear Information System (INIS)

    Strenge, D.L.; Chamberlain, P.J. II.

    1994-11-01

    This report describes the generation of unit risk factors for use with the Graphical Information System (GIS) being developed by Advanced Sciences, Inc. for the Hanford Remedial Action Environmental Impact Statement. The GIS couples information on source inventory and environmental transport with unit risk factors to estimate the potential risk from contamination at all locations on the Hanford Site. The major components of the effort to generate the unit risk factors were: determination of pollutants to include in the study, definition of media of concern, and definition of exposure assessment scenarios, methods, and parameters. The selection of pollutants was based on inventory lists which indicated the pollutants likely to be encountered at the known waste sites. The final pollutants selected included 47 chemical pollutants and 101 radionuclides. Unit risk factors have been generated for all 148 pollutants per unit initial concentration in five media: soil (per unit mass), soil (per unit area), air, groundwater, and surface water. The exposure scenarios were selected as the basis for the unit risk factor generation. The endpoint in the exposure assessment analysis is expressed as risk of developing cancer for radionuclides and carcinogenic chemicals. For noncarcinogenic chemicals, the risk endpoint is the hazard quotient. The cancer incidence and hazard quotient values are evaluated for all exposure pathways, pollutants, and scenarios. The hazard index values and unit risk values are used by the GIS to produce maps of risk for the Hanford Site

  20. Information needs for risk assessment

    Energy Technology Data Exchange (ETDEWEB)

    DeRosa, C.T.; Choudhury, H.; Schoeny, R.S.

    1990-12-31

    Risk assessment can be thought of as a conceptual approach to bridge the gap between the available data and the ultimate goal of characterizing the risk or hazard associated with a particular environmental problem. To lend consistency to and to promote quality in the process, the US Environmental Protection Agency (EPA) published Guidelines for Risk Assessment of Carcinogenicity, Developmental Toxicity, Germ Cell Mutagenicity and Exposure Assessment, and Risk Assessment of Chemical Mixtures. The guidelines provide a framework for organizing the information, evaluating data, and for carrying out the risk assessment in a scientifically plausible manner. In the absence of sufficient scientific information or when abundant data are available, the guidelines provide alternative methodologies that can be employed in the risk assessment. 4 refs., 3 figs., 2 tabs.