Receptor-interacting protein (RIP) kinase family

OpenAIRE

Zhang, Duanwu; Lin, Juan; Han, Jiahuai

2010-01-01

Receptor-interacting protein (RIP) kinases are a group of threonine/serine protein kinases with a relatively conserved kinase domain but distinct non-kinase regions. A number of different domain structures, such as death and caspase activation and recruitment domain (CARD) domains, were found in different RIP family members, and these domains should be keys in determining the specific function of each RIP kinase. It is known that RIP kinases participate in different biological processes, incl...

Fiscal Year 2013 Revegetation Assessment

Energy Technology Data Exchange (ETDEWEB)

Nordstrom, Jenifer [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2013-11-01

This report summarizes the Fiscal Year 2013 Revegetation Assessment by Battelle Energy Alliance, LLC. This assessment was conducted to supplement documentation related to the Storm Water Pollution Prevention Plan for Construction Activities and to ensure that disturbed vegetation and soil at various locations are being restored. This report provides the following information for each site being monitored by the Idaho National Laboratory Environmental Support and Services: Summary of each site Assessment of vegetation status and site stabilization at each location Actions and Resolutions for each site. Six disturbed sites were evaluated for this assessment. One has achieved final stabilization. The remaining five sites not meeting the criteria for final stabilization will be evaluated again in the next fiscal year.

Observations on the U.S. Agency for International Development's Fiscal Year 1999 Performance Report and Fiscal Years 2000 and 2001 Performance Plans

National Research Council Canada - National Science Library

2000-01-01

As you requested, we have reviewed the 24 Chief Financial Officers (CFO) Act agencies' fiscal year 1999 performance reports and fiscal year 2001 performance plans required by the Government Performance and Results Act of 1993 (GPRA...

Rip current related drowning deaths and rescues in Australia 2004-2011

Science.gov (United States)

Brighton, B.; Sherker, S.; Brander, R.; Thompson, M.; Bradstreet, A.

2013-04-01

Rip currents are a common hazard to beachgoers found on many beaches around the world, but it has proven difficult to accurately quantify the actual number of rip current related drowning deaths in many regions and countries. Consequently, reported estimates of rip current drowning can fluctuate considerably and are often based on anecdotal evidence. This study aims to quantify the incidence of rip current related drowning deaths and rescues in Australia from 2004 to 2011. A retrospective search was undertaken for fatal and non-fatal rip-related drowning incidents from Australia's National Coronial Information System (NCIS), Surf Life Saving Australia's (SLSA, 2005-2011) SurfGuard Incident Report Database (IRD), and Media Monitors for the period 1 July 2004 to 30 June 2011. In this time, rip currents were recorded as a factor in 142 fatalities of a total of 613 coastal drowning deaths (23.2%), an average of 21 per year. Rip currents were related to 44% of all beach-related drowning deaths and were involved in 57.4% of reported major rescues in Australian locations where rips occur. A comparison with international operational statistics over the same time period describes rip-related rescues as 53.7% of the total rescues in the US, 57.9% in the UK and 49.4% in New Zealand. The range 49-58% is much lower than 80-89% traditionally cited. The results reported are likely to underestimate the size of the rip current hazard, because we are limited by the completeness of data on rip-related events; however this is the most comprehensive estimate to date. Beach safety practitioners need improved data collection and standardized definitions across organisations. The collection of drowning data using consistent categories and the routine collection of rip current information will allow for more accurate global comparisons.

42 CFR 412.64 - Federal rates for inpatient operating costs for Federal fiscal year 2005 and subsequent fiscal...

Science.gov (United States)

2010-10-01

... prospective payment rate is based on the geographic location of the hospital facility at which the discharge... percentage change for updating the standardized amount is— (i) For fiscal year 2005 through fiscal year 2009... adjust the standardized amount for subsequent fiscal years so as to eliminate the effect of such coding...

Accountability report - fiscal year 1997

International Nuclear Information System (INIS)

1998-01-01

This document contains the US NRC's accountability report for fiscal year 1997. Topics include uses of funds, financial condition, program performance, management accountability, and the audited financial statement

Accountability report - fiscal year 1997

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-04-01

This document contains the US NRC`s accountability report for fiscal year 1997. Topics include uses of funds, financial condition, program performance, management accountability, and the audited financial statement.

Yearly (Fiscal) Historical Electronic Services Report

Data.gov (United States)

Social Security Administration — This report contains yearly electronic services data for online applications. This report is updated monthly for the current fiscal year. The report is divided into...

Fiscal Year 2012 Revegetation Assessment

Energy Technology Data Exchange (ETDEWEB)

Jenifer Nordstrom

2012-11-01

This report summarizes the Fiscal Year 2012 Revegetation Assessment by Battelle Energy Alliance, LLC. This assessment was conducted to supplement documentation related to the Storm Water Pollution Prevention Plan for Construction Activities and to ensure that disturbed vegetation and soil at various locations are being restored. This report provides the following information for each site being monitored by the Idaho National Laboratory Environmental Support and Services: • Summary of each site • Assessment of vegetation status and site stabilization at each location • Actions and Resolutions for each site. Ten disturbed sites were evaluated for this assessment. Six have achieved final stabilization. The remaining four sites not meeting the criteria for final stabilization will be evaluated again in the next fiscal year.

Spending Disclosure - Fiscal Year 2012

Data.gov (United States)

Montgomery County of Maryland — The purpose of this Spending Disclosure Fiscal Year 12 dataset is to allow the public to search and view summary information on payments made to recipients (referred...

Water-resources activities, North Dakota District, fiscal year 1990

Science.gov (United States)

Martin, Cathy R.

1991-01-01

The mission of the U.S. Geological Survey, Water Resources Division, is to provide the hydrologic information and understanding needed for the optimum utilization and management of the Nation's water resources for the overall benefit of the people of the United States. This report describes waterresources activities of the Water Resources Division in North Dakota in fiscal year 1990. Information on each project includes objectives, approach, progress in fiscal year 1990, plans for fiscal year 1991, completed and planned report products, and the name of the project chief.

Environment, safety, health at DOE Facilities. Annual report, Fiscal Year 1980

International Nuclear Information System (INIS)

1981-07-01

The Department of Energy's occupational safety and property protection performance in fiscal year 1980 was excellent in all reported categories with loss rates generally less than one-third of comparable industry figures. The Department of Energy's fiscal year 1980 incidence rate per 200,000 work hours was 1.1 lost workday cases and 18.2 lost workdays compared to 1.1 lost workday cases and 17.2 lost workdays during fiscal year 1979. The recorded occupational illness rate, based on only 70 cases, was 0.05 cases per 200,000 work hours compared to 0.06 cases per 200,000 work hours for fiscal year 1979. Ten fatalities involving Federal or contractor employees occurred in fiscal year 1980 compared to nine for fiscal year 1979. Four of those in fiscal year 1980 resulted from two aircraft accidents. Total reported property loss during fiscal year 1980 was $7.1 million with $3.5 million attributable to earthquake damage sustained by the Lawrence Livermore and Sandia National Laboratories on January 24, 1980. A total of 131 million vehicle miles of official vehicular travel during fiscal year 1980 resulted in 768 accidents and $535,145 in property damages. The 104,986 monitored Department of Energy and Department of Energy contractor employees received a total dose of 9040 REM in calendar year 1979. Both the total dose and the 1748 employees receiving radiation exposures greater than 1 REM in 1979 represent a continuing downward trend from the calendar year 1978 total dose of 9380 REM and the 1826 employees who received radiation exposures greater than 1 REM. The fifty-nine appraisals conducted indicate that generally adequate plans have been developed and effective organizational structures have been established to carry out the Department of Energy's Environmental Protection, Safety, and Health Protection (ES and H) Program

Budget estimates fiscal year 1995: Volume 10

International Nuclear Information System (INIS)

1994-02-01

This report contains the Nuclear Regulatory Commission (NRC) fiscal year budget justification to Congress. The budget provides estimates for salaries and expenses and for the Office of the Inspector General for fiscal year 1995. The NRC 1995 budget request is $546,497,000. This is an increase of $11,497,000 above the proposed level for FY 1994. The NRC FY 1995 budget request is 3,218 FTEs. This is a decrease of 75 FTEs below the 1994 proposed level

Budget estimates fiscal year 1995: Volume 10

Energy Technology Data Exchange (ETDEWEB)

1994-02-01

This report contains the Nuclear Regulatory Commission (NRC) fiscal year budget justification to Congress. The budget provides estimates for salaries and expenses and for the Office of the Inspector General for fiscal year 1995. The NRC 1995 budget request is $546,497,000. This is an increase of $11,497,000 above the proposed level for FY 1994. The NRC FY 1995 budget request is 3,218 FTEs. This is a decrease of 75 FTEs below the 1994 proposed level.

Groundwater Annual Status Report for Fiscal Year 1998

International Nuclear Information System (INIS)

A. K. Stoker; A. S. Johnson; B. D. Newman; B. M. Gallaher; C. L. Nylander; D. B. Rogers; D. E. Broxton; D. Katzman; E. H. Keating; G. L. Cole; K. A. Bitner; K. I. Mullen; P. Longmire; S. G. McLin; W. J. Stone

1999-01-01

Groundwater protection activities and hydrogeologic characterization studies are conducted at LANL annually. A summary of fiscal year 1998 results and findings shows increased understanding of the hydrogeologic environment beneath the Pajarito Plateau and significant refinement to elements of the LANL Hydrogeologic Conceptual Model pertaining to areas and sources of recharge to the regional aquifer. Modeling, drilling, monitoring, and data collection activities are proposed for fiscal year 1999

77 FR 29317 - Fiscal Year 2011 Draft Work Plan

Science.gov (United States)

2012-05-17

... DENALI COMMISSION Fiscal Year 2011 Draft Work Plan AGENCY: Denali Commission. ACTION: Notice... develop proposed work plans for future spending and that the annual Work Plan be published in the Federal... Work Plan for Federal Fiscal Year 2011. DATES: Comments and related material to be received by June 10...

77 FR 29317 - Fiscal Year 2012 Draft Work Plan

Science.gov (United States)

2012-05-17

... DENALI COMMISSION Fiscal Year 2012 Draft Work Plan AGENCY: Denali Commission. ACTION: Notice... Commission develop proposed work plans for future spending and that the annual Work Plan be published in the... Commission Draft Work Plan for Federal Fiscal Year 2012. DATES: Comments and related material to be received...

FISCAL YEAR 2003 BUDGET REQUEST. U.S. General Accounting Office

National Research Council Canada - National Science Library

2002-01-01

.... General Accounting Office (GAO) to report on GAO's fiscal year 2001 performance and results, current challenges and future plans, and budget request for fiscal year 2003 to support the Congress and serve the American public...

Groundwater Annual Status Report for Fiscal Year 1999

International Nuclear Information System (INIS)

Nylander, C.L.; Bitner, K.A.; Henning, K.; Johnson, A.S.; Keating, E.H.; Longmire, P.; Newman, B.D.; Robinson, B.; Rogers, D.B.; Stone, W.J.; Vaniman, D.

2000-01-01

Groundwater protection activities and hydrogeologic characterization studies are conducted at Los Alamos National Laboratory annually. A summary of fiscal year 1999 results and findings shows increased understanding of the hydrogeologic environment beneath the Pajarito Plateau and significant refinement to elements of the LANL. Hydrogeologic Conceptual Model pertaining to areas and sources of recharge to the regional aquifer. Modeling, drilling, monitoring, and data collection activities are proposed for fiscal year 2000

Death and Lulz: Understanding the personality characteristics of RIP trolls

OpenAIRE

Seigfried-Spellar, Kathryn C.; Chowdhury, Siddharth S.

2017-01-01

Trolling on the Internet is a form of deviant behavior that borderlines cyberharassment. A specific type of trolling behavior involving individuals posting rude/harassing comments on online memorial pages is known as RIP or memorial page trolling. This study compared the personality traits of self-reported RIP trolls to other trolls who did not engage in RIP trolling (non-RIP trolls); 30 respondents were classified as RIP trolls and 119 respondents as non-RIP trolls. Results indicated RIP tro...

Budget estimates, fiscal year 1984/85. Appropriation: salaries and expenses

International Nuclear Information System (INIS)

1983-01-01

This report contains the fiscal year budget justifications to Congress. The budget estimates for salaries and expenses for fiscal year 1984 to 1985 provide for obligations of $466,800,000 to be funded in total by a new appropriation

Fleet Compliance Annual Report: Model Year 2015, Fiscal Year 2016

Energy Technology Data Exchange (ETDEWEB)

None

2016-12-01

The U.S. Department of Energy (DOE) regulates covered state government and alternative fuel provider fleets, pursuant to the Energy Policy Act of 1992 (EPAct), as amended. This report details compliance for model year 2015, fiscal year 2016.

Fiscal Year 2008 Agency Financial Report

National Research Council Canada - National Science Library

2008-01-01

The Department of Defense (DoD) Fiscal Year (FY) 2008 Agency Financial Report (AFR) provides the President, Congress, other federal departments and agencies, and the American public an overview of the Department's financial condition...

Operational accidents and radiation exposures at DOE facilities. Fiscal year 1979

International Nuclear Information System (INIS)

1980-12-01

The Department of Energy's safety performance in fiscal year 1979 showed improvement in all categories over fiscal year 1978. The loss rates were less than one-half the United States industry average as reported by the National Safety Council. Incidence rates per 200,000 workhours were 1.1 lost workday cases and 17.2 lost workdays compared to 1.2 lost workday cases and 17.6 lost workdays during fiscal year 1978. The recordable occupational illness rate, based on only 80 cases, was 0.06 cases per 200,000 workhours compared to 0.07 cases per 200,000 workhours for fiscal year 1978. Nine fatalities of contractor employees resulted in an annual rate of 6.0 deaths per 100,000 workers compared with 10 fatalities during fiscal year 1978, and an annual rate of 6.7 deaths per 100,000 workers. The total Department of Energy property loss reported during fiscal year 1979 was $3.3 million; $765,400 was caused by fire, and $2.5 million by other causes. A total of 121 million vehicle miles of official travel resulted in 685 accidents with $338,400 in property damage. The loss rates of 5.7 accidents per million vehicle miles and $2.80 per 1000 miles were improvements over the fiscal year 1978 rates of 5.8 accidents per million vehicle miles and $2.97 property damage per 1000 miles. The 104,986 monitored Department of Energy and its contractor employees received a total dose of 9040 rem in calendar year 1979. Both the total dose and the 1748 employees receiving radiation exposures greater than 1 rem in 1979 represent a continuing downward trend from the calendar year 1978 total dose of 9380 rem and the 1826 employees who received radiation exposures greater than 1 rem

Research and examinations at the Tono Mines. Fiscal year's programs (Heisei 12 fiscal year). Technical report

International Nuclear Information System (INIS)

2000-04-01

This program showed details on the research and examination program of the Japan Nuclear Cycle Development Institute to be carried out at the Tono Mines in the Heisei 12 fiscal year, according to the 'Fundamental program on research and examinations at the Tono Mines' established on October, 1998. And, this program is carried out under an aim at understanding of transfer and delay performance of materials in deposit rocks with uranium and geological features such as fault, and at development of technology and apparatus for general investigation and evaluation of geological environment, as a stratum science research. Here were described on research and examination of mechanical stability on the rock board, research and examination of geological environment around a tunnel, research and examination of material transfer in the rock board, and research and examination of the Tsukiyoshi stratum abstractly before 1999 and in details at 2000 fiscal years. (G.K.)

Federal Facility Agreement Annual Progress Report for Fiscal Year 1998

International Nuclear Information System (INIS)

Palmer, E.

1999-01-01

This FFA Annual Progress Report has been developed to summarize the information for activities performed during the Fiscal Year 1998 (October 1, 1997, to September 30, 1998) and activities planned for Fiscal Year 1999 by U.S. EPA, SCDHEC, and SRS at those units and areas identified for remediation in the Agreement

77 FR 28614 - Fiscal Year (FY) 2012 Funding Opportunity

Science.gov (United States)

2012-05-15

... Services Administration (SAMHSA) intends to award approximately $130,000 (total costs) for up to one year... training. The purpose of the supplemental funding is to provide logistical and fiscal management support...: Develop a plan to provide logistical and fiscal management support for project-related activities in Iraq...

78 FR 62415 - Refugee Admissions for Fiscal Year 2014

Science.gov (United States)

2013-10-21

... October 2, 2013 Refugee Admissions for Fiscal Year 2014 Memorandum for the Secretary of State In... authorize the following actions: The admission of up to 70,000 refugees to the United States during fiscal... with Federal refugee resettlement assistance under the Amerasian immigrant admissions program, as...

Forcing and variability of nonstationary rip currents

Science.gov (United States)

Long, Joseph W.; H.T. Özkan-Haller,

2016-01-01

Surface wave transformation and the resulting nearshore circulation along a section of coast with strong alongshore bathymetric gradients outside the surf zone are modeled for a consecutive 4 week time period. The modeled hydrodynamics are compared to in situ measurements of waves and currents collected during the Nearshore Canyon Experiment and indicate that for the entire range of observed conditions, the model performance is similar to other studies along this stretch of coast. Strong alongshore wave height gradients generate rip currents that are observed by remote sensing data and predicted qualitatively well by the numerical model. Previous studies at this site have used idealized scenarios to link the rip current locations to undulations in the offshore bathymetry but do not explain the dichotomy between permanent offshore bathymetric features and intermittent rip current development. Model results from the month‐long simulation are used to track the formation and location of rip currents using hourly statistics, and results show that the direction of the incoming wave energy strongly controls whether rip currents form. In particular, most of the offshore wave spectra were bimodal and we find that the ratio of energy contained in each mode dictates rip current development, and the alongshore rip current position is controlled by the incident wave period. Additionally, model simulations performed with and without updating the nearshore morphology yield no significant change in the accuracy of the predicted surf zone hydrodyanmics indicating that the large‐scale offshore features (e.g., submarine canyon) predominately control the nearshore wave‐circulation system.

Degree of anisotropy as an automated indicator of rip channels in high resolution bathymetric models

Science.gov (United States)

Trimble, S. M.; Houser, C.; Bishop, M. P.

2017-12-01

A rip current is a concentrated seaward flow of water that forms in the surf zone of a beach as a result of alongshore variations in wave breaking. Rips can carry swimmers swiftly into deep water, and they are responsible for hundreds of fatal drownings and thousands of rescues worldwide each year. These currents form regularly alongside hard structures like piers and jetties, and can also form along sandy coasts when there is a three dimensional bar morphology. This latter rip type tends to be variable in strength and location, making them arguably the most dangerous to swimmers and most difficult to identify. These currents form in characteristic rip channels in surf zone bathymetry, in which the primary axis of self-similarity is oriented shore-normal. This paper demonstrates a new method for automating identification of such rip channels in bathymetric digital surface models (DSMs) using bathymetric data collected by various remote sensing methods. Degree of anisotropy is used to detect rip channels and distinguishes between sandbars, rip channels, and other beach features. This has implications for coastal geomorphology theory and safety practices. As technological advances increase access and accuracy of topobathy mapping methods in the surf zone, frequent nearshore bathymetric DSMs could be more easily captured and processed, then analyzed with this method to result in localized, automated, and frequent detection of rip channels. This could ultimately reduce rip-related fatalities worldwide (i) in present mitigation, by identifying the present location of rip channels, (ii) in forecasting, by tracking the channel's evolution through multiple DSMs, and (iii) in rip education by improving local lifeguard knowledge of the rip hazard. Although this paper on applies analysis of degree of anisotropy to the identification of rip channels, this parameter can be applied to multiple facets of barrier island morphological analysis.

77 FR 32977 - Announcement of Funding Awards for Fiscal Year 2012 Transformation Initiative: Choice...

Science.gov (United States)

2012-06-04

... Awards for Fiscal Year 2012 Transformation Initiative: Choice Neighborhoods Demonstration Small Research... awards for the Fiscal Year (FY) 2012 Transformation Initiative: Choice Neighborhoods Demonstration Small... Under the Fiscal Year 2012 Transformation Initiative: Choice Neighborhoods Demonstration Small Research...

7 CFR 1215.7 - Fiscal year.

Science.gov (United States)

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Fiscal year. 1215.7 Section 1215.7 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION Popcorn Promotion, Research, and Consumer Information Order Definitions § 1215.7...

7 CFR 1209.7 - Fiscal year.

Science.gov (United States)

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Fiscal year. 1209.7 Section 1209.7 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION ORDER Mushroom Promotion, Research, and Consumer Information Order Definitions § 1209...

Budget of the U.S. Government, Fiscal Year 2013

Science.gov (United States)

Office of Management and Budget, Executive Office of the President, 2012

2012-01-01

"Budget of the United States Government, Fiscal Year 2013" contains the Budget Message of the President, information on the President's priorities, budget overviews organized by agency, and summary tables. The 2013 Budget contains a number of steps to put the country on a fiscally sustainable path. First, this Budget implements the tight…

78 FR 7858 - Publication of Fiscal Year 2012 Service Contract Inventory

Science.gov (United States)

2013-02-04

... DEPARTMENT OF THE TREASURY Publication of Fiscal Year 2012 Service Contract Inventory AGENCY: Departmental Offices, Treasury. ACTION: Notice of publication of Fiscal Year 2012 Service Contract Inventory. SUMMARY: The Department of the Treasury will make available to the public at http://www.treasury.gov/about...

Water-resources activities, North Dakota District, Fiscal Year 1992

Science.gov (United States)

Martin, Cathy R.

1993-01-01

The mission of the U.S. Geological Survey, Water Resources Division, is to provide the hydrologic information and understanding needed for the optimum utilization and management of the Nation's water resources for the overall benefit of the people of the United States. This report describes water-resources activities of the Water Resources Division in North Dakota in fiscal year 1992. Information on each project includes objectives, approach, progress, plans for fiscal year 1993, and completed and planned report products.

United States Department of Education: Annual Accountability Report, Fiscal Year 1995.

Science.gov (United States)

Department of Education, Washington, DC.

Fiscal year 1995 marks the first year during which an independent audit was conducted of the U.S. Department of Education's financial statements. This first annual accountability report describes the department's history, current mission, priorities, and progress. It highlights the department's program and fiscal accomplishments and describes…

Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells.

Science.gov (United States)

Sun, Wen; Wu, Xiaxia; Gao, Hongwei; Yu, Jie; Zhao, Wenwen; Lu, Jin-Jian; Wang, Jinhua; Du, Guanhua; Chen, Xiuping

2017-07-01

Necroptosis is a form of programmed necrosis mediated by signaling complexes with receptor-interacting protein 1 (RIP1) and RIP3 kinases as the main mediators. However, the underlying execution pathways of this phenomenon have yet to be elucidated in detail. In this study, a RIP1/RIP3 complex was formed in 2-methoxy-6-acetyl-7-methyljuglone (MAM)-treated HCT116 and HT29 colon cancer cells. With this formation, mitochondrial reactive oxygen species (ROS) levels increased, mitochondrial depolarization occurred, and ATP concentrations decreased. This process was identified as necroptosis. This finding was confirmed by experiments showing that MAM-induced cell death was attenuated by the pharmacological or genetic blockage of necroptosis signaling, including RIP1 inhibitor necrostatin-1s (Nec-1s) and siRNA-mediated gene silencing of RIP1 and RIP3, but was unaffected by caspase inhibitor z-vad-fmk or necrosis inhibitor 2-(1H-Indol-3-yl)-3-pentylamino-maleimide (IM54). Transmission electron microscopy (TEM) analysis further revealed the ultrastructural features of MAM-induced necroptosis. MAM-induced RIP1/RIP3 complex triggered necroptosis through cytosolic calcium (Ca 2+ ) accumulation and sustained c-Jun N-terminal kinase (JNK) activation. Both calcium chelator BAPTA-AM and JNK inhibitor SP600125 could attenuate necroptotic features, including mitochondrial ROS elevation, mitochondrial depolarization, and ATP depletion. 2-thenoyltrifluoroacetone (TTFA), which is a mitochondrial complex II inhibitor, was found to effectively reverse both MAM induced mitochondrial ROS generation and cell death, indicating the complex II was the ROS-producing site. The essential role of mitochondrial ROS was confirmed by the protective effect of overexpression of manganese superoxide dismutase (MnSOD). MAM-induced necroptosis was independent of TNFα, p53, MLKL, and lysosomal membrane permeabilization. In summary, our study demonstrated that RIP1/RIP3 complex-triggered cytosolic calcium

42 CFR 412.211 - Puerto Rico rates for Federal fiscal year 2004 and subsequent fiscal years.

Science.gov (United States)

2010-10-01

... payment system for which payment may be made under Medicare Part A. (b) Geographic classifications. (1... standards are set forth in the notice of final revised standards for classification of MSAs published in the... each discharge classified within a DRG, CMS establishes for the fiscal year a Puerto Rico prospective...

A Role of RIP3-Mediated Macrophage Necrosis in Atherosclerosis Development

Directory of Open Access Journals (Sweden)

Juan Lin

2013-01-01

Full Text Available Necrotic death of macrophages has long been known to be present in atherosclerotic lesions but has not been studied. We examined the role of receptor interacting protein (RIP 3, a mediator of necrotic cell death, in atherosclerosis and found that RIP3−/−;Ldlr−/− mice were no different from RIP3+/+;Ldlr−/− mice in early atherosclerosis but had significant reduction in advanced atherosclerotic lesions. Similar results were observed in Apoe−/− background mice. Bone marrow transplantation revealed that loss of RIP3 expression from bone-marrow-derived cells is responsible for the reduced disease progression. While no difference was found in apoptosis between RIP3−/−;Ldlr−/− and RIP3+/+;Ldlr−/− mice, electron microscopy revealed a significant reduction of macrophage primary necrosis in the advanced lesions of RIP3−/− mice. In vitro cellular studies showed that RIP3 deletion had no effect on oxidized low-density lipoprotein (LDL-induced macrophage apoptosis, but prevented macrophage primary necrosis occurring in response to oxidized LDL under caspase inhibition or RIP3 overexpression conditions. RIP3-dependent necrosis is not postapoptotic, and the increased primary necrosis in advanced atherosclerotic lesions most likely resulted from the increase of RIP3 expression. Our data demonstrate that primary necrosis of macrophages is proatherogenic during advanced atherosclerosis development.

Ecological Monitoring and Compliance Program Fiscal/Calendar Year 2004 Report

Energy Technology Data Exchange (ETDEWEB)

Bechtel Nevada

2005-03-01

The Ecological Monitoring and Compliance program, funded through the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office, monitors the ecosystem of the Nevada Test Site and ensures compliance with laws and regulations pertaining to Nevada Test Site biota. This report summarizes the program's activities conducted by Bechtel Nevada during the Fiscal Year 2004 and the additional months of October, November, and December 2004, reflecting a change in the monitoring period to a calendar year rather than a fiscal year as reported in the past. This change in the monitoring period was made to better accommodate information required for the Nevada Test Site Environmental Report, which reports on a calendar year rather than a fiscal year. Program activities included: (1) biological surveys at proposed construction sites, (2) desert tortoise compliance, (3) ecosystem mapping and data management, (4) sensitive species and unique habitat monitoring, (5) habitat restoration monitoring, and (6) biological monitoring at the Hazardous Materials Spill Center.

FAA aviation forecasts : fiscal years 1997-2008

Science.gov (United States)

1997-03-01

This report contains the Fiscal Years 1997-2008 Federal Aviation Administration (FAA) forecasts of aviation activity at FAA facilities. These include airports with both FAA and contract control towers, air route traffic control centers, and flight se...

CREATING INPUT TABLES FROM WAPDEG FOR RIP

International Nuclear Information System (INIS)

K.G. Mon

1998-01-01

The purpose of this calculation is to create tables for input into RIP ver. 5.18 (Integrated Probabilistic Simulator for Environmental Systems) from WAPDEG ver. 3.06 (Waste Package Degradation) output. This calculation details the creation of the RIP input tables for TSPA-VA REV.00

78 FR 14415 - Publication of Fiscal Year 2012 Service Contract Inventory Analysis

Science.gov (United States)

2013-03-05

... DEPARTMENT OF THE TREASURY Publication of Fiscal Year 2012 Service Contract Inventory Analysis AGENCY: Departmental Offices, Treasury. ACTION: Notice of publication of Fiscal Year 2012 Service Contract Inventory: Analysis of the FY 2012 Inventory and Planned Analysis of 2013. SUMMARY: The Department...

Homogeneous and isotropic big rips?

CERN Document Server

Giovannini, Massimo

2005-01-01

We investigate the way big rips are approached in a fully inhomogeneous description of the space-time geometry. If the pressure and energy densities are connected by a (supernegative) barotropic index, the spatial gradients and the anisotropic expansion decay as the big rip is approached. This behaviour is contrasted with the usual big-bang singularities. A similar analysis is performed in the case of sudden (quiescent) singularities and it is argued that the spatial gradients may well be non-negligible in the vicinity of pressure singularities.

Rip current monitoring using GPS buoy system

Science.gov (United States)

Song, DongSeob; Kim, InHo; Kang, DongSoo

2014-05-01

The occurrence of rip current in the Haeundae beach, which is one of the most famous beaches in South Korea, has been threatening beach-goers security in summer season annually. Many coastal scientists have been investigating rip currents by using field observations and measurements, laboratory measurements and wave tank experiments, and computer and numerical modeling. Rip current velocity is intermittent and may rapidly increase within minutes due to larger incoming wave groups or nearshore circulation instabilities. It is important to understand that changes in rip current velocity occur in response to changes in incoming wave height and period as well as changes in water level. GPS buoys have been used to acquire sea level change data, atmospheric parameters and other oceanic variables in sea for the purposes of vertical datum determination, tide correction, radar altimeter calibration, ocean environment and marine pollution monitoring. Therefore, we adopted GPS buoy system for an experiment which is to investigate rip current velocity; it is sporadic and may quickly upsurge within minutes due to larger arriving wave groups or nearshore flow uncertainties. In this study, for high accurate positioning of buy equipment, a Satellite Based Argumentation System DGPS data logger was deployed to investigate within floating object, and it can be acquired three-dimensional coordinate or geodetic position of buoy with continuous NMEA-0183 protocol during 24 hours. The wave height measured by in-situ hydrometer in a cross-shore array clearly increased before and after occurrence of rip current, and wave period also was lengthened around an event. These results show that wave height and period correlate reasonably well with long-shore current interaction in the Haeundae beach. Additionally, current meter data and GPS buoy data showed that rip current velocities, about 0.2 m/s, may become dangerously strong under specific conditions. Acknowledgement This research was

Water-resources activities, North Dakota District, fiscal year 1994-95

Science.gov (United States)

Martin, Cathy R.

1995-01-01

The mission of the U.S. Geological Survey, Water Resources Division, is to provide the hydrologic information and understanding needed for the optimum utilization and management of the Nation's water resources for the overall benefit of the people of the United States. This report describes water-resources activities of the Water Resources Division in North Dakota in fiscal year 1994. Information on each project includes objectives, approach, progress, plans for fiscal year 1995, and completed and planned report products.

Environmental radioactivity survey in Fukuoka prefecture. Fiscal year 1963-1990

International Nuclear Information System (INIS)

Narazaki, Yukinori; Nakayama, Kazushige; Karube, Yoshiharu.

1995-01-01

This report summarizes the analytical results of deposition, soil and total diet in regard to 90 Sr and 137 Cs concentrations in the area of Fukuoka prefecture during the period of fiscal year 1963-1990 as well as measurements of the γ-ray dose rate in the same area during the period of fiscal year 1970-1990. The annual fallout peaked value in fiscal year 1963 and then decreased on an exponential curve until fiscal year 1985, reflecting the effect of Chinese nuclear tests. 137 Cs fallout at a level of 34.4 MBq/km 2 was detected upon the accident at the Chernobyl nuclear power plant in 1986. However, it began to decrease in the following year and had shown a lower annual level since fiscal year 1989 than those which were detected before the accident. The results of soil analysis showed a sign of accumulation of both 90 Sr and 137 Cs, indicating a long-term effect. The radioactivity of the two nuclides in total diet showed a sloping down curve similar to that of the deposition. The γ-ray dose rate was in the range 51.3-101 nGy/h, averaging 70.7±5.24 nGy/h. The dose equivalent due to external exposure to 137 Cs in the soil was estimated to be 14.5 μSv/year on average and that due to internal exposure to 90 Sr and 137 Cs was 4.7 μSv/year on average. It was found that the 90 Sr and 137 Cs concentration levels in the fallout in Fukuoka prefecture were lower than that of the national average and the mean dose equivalent due to both internal and external exposure to the two nuclides was estimated to be 18.0 μSv/year. This value is within the error limit of 0.495±0.0367 mSv/year, which represents an annual dose equivalent due to the γ-ray dose rate, and is less than 1% of the dose of 2.4 mSv/year, which represents the mean dose due to the total natural radiation in the world. (J.P.N.)

Budget estimates fiscal year 1989: Appropriation, Salaries and expenses

International Nuclear Information System (INIS)

1988-02-01

The budget estimates for Salaries and Expenses for FY 1989 provide for obligations of $450,000,000 to be funded in total by a new appropriation. The sum appropriated shall be reduced by the amount of revenues received during fiscal year 1989 from licensing fees, inspection services, and other services and collections, excluding those monies received for the cooperative nuclear safety research program, services rendered to foreign governments and international organizations, and the material and information access authorization programs, so as to result in a final fiscal year 1989 appropriation estimated at not more than $247,500,000

Nuclear fuels technologies Fiscal Year 1996 research and development test results

International Nuclear Information System (INIS)

Beard, C.A.; Blair, H.T.; Buksa, J.J.; Butt, D.P.; Chidester, K.; Eaton, S.L.; Farish, T.J.; Hanrahan, R.J.; Ramsey, K.B.

1996-11-01

During fiscal year 1996, the Department of Energy's Office of Fissile Materials Disposition (OFMD) funded Los Alamos National Laboratory (LANL) to investigate issues associated with the fabrication of plutonium from dismantled weapons into mixed-oxide (MOX) nuclear fuel for disposition in nuclear power reactors. These issues can be divided into two main categories: issues associated with the fact that the plutonium from dismantled weapons contains gallium, and issues associated with the unique characteristics of the PuO[sub 2] produced by the dry conversion process that OFMD is proposing to convert the weapons material. Initial descriptions of the experimental work performed in fiscal year 1996 to address these issues can be found in Nuclear Fuels Technologies Fiscal Year 1996 Research and Development Test Matrices. However, in some instances the change in programmatic emphasis towards the Parallex program either altered the manner in which some of these experiments were performed (i.e., the work was done as part of the Parallex fabrication development and not as individual separate-effects tests as originally envisioned) or delayed the experiments into Fiscal Year 1997. This report reviews the experiments that were conducted and presents the results

76 FR 26805 - Medicare Program; Hospice Wage Index for Fiscal Year 2012

Science.gov (United States)

2011-05-09

..., and hospices in low-wage index areas are unfairly advantaged. The commenter felt that our not wage... Medicare & Medicaid Services 42 CFR Part 418 Medicare Program; Hospice Wage Index for Fiscal Year 2012... [CMS-1355-P] RIN 0938-AQ31 Medicare Program; Hospice Wage Index for Fiscal Year 2012 AGENCY: Centers...

Telephone Interpreter Services (TIS) - Asian and Pacific Islander (API) Language Fiscal Year Quarterly Dataset

Data.gov (United States)

Social Security Administration — This dataset displays our quarterly national TIS call volume for over 45 API languages for fiscal year 2013 onward. A fiscal year runs from October through September...

76 FR 375 - Notice of Availability: Notice of Funding Availability (NOFA) for Fiscal Year 2010; Historically...

Science.gov (United States)

2011-01-04

...: Notice of Funding Availability (NOFA) for Fiscal Year 2010; Historically Black Colleges and Universities... Fiscal Year 2010. This NOFA is governed by the information and instructions found in HUD's Fiscal Year 2010 Notice of Funding Availability (NOFA) Policy Requirements and General Section that HUD issued on...

Naval Petroleum and Oil Shale Reserves. Annual report of operations, Fiscal year 1993

International Nuclear Information System (INIS)

1993-01-01

During fiscal year 1993, the reserves generated $440 million in revenues, a $33 million decrease from the fiscal year 1992 revenues, primarily due to significant decreases in oil and natural gas prices. Total costs were $207 million, resulting in net cash flow of $233 million, compared with $273 million in fiscal year 1992. From 1976 through fiscal year 1993, the Naval Petroleum and Oil Shale Reserves generated $15.7 billion in revenues for the US Treasury, with expenses of $2.9 billion. The net revenues of $12.8 billion represent a return on costs of 441 percent. See figures 2, 3, and 4. In fiscal year 1993, production at the Naval Petroleum and Oil Shale Reserves at maximum efficient rates yielded 25 million barrels of crude oil, 123 billion cubic feet of natural gas, and 158 million gallons of natural gas liquids. The Naval Petroleum and Oil Shale Reserves has embarked on an effort to identify additional hydrocarbon resources on the reserves for future production. In 1993, in cooperation with the US Geological Survey, the Department initiated a project to assess the oil and gas potential of the program's oil shale reserves, which remain largely unexplored. These reserves, which total a land area of more than 145,000 acres and are located in Colorado and Utah, are favorably situated in oil and gas producing regions and are likely to contain significant hydrocarbon deposits. Alternatively the producing assets may be sold or leased if that will produce the most value. This task will continue through the first quarter of fiscal year 1994

Hanford Site Groundwater Monitoring for Fiscal Year 2004

Energy Technology Data Exchange (ETDEWEB)

Hartman, Mary J.; Morasch, Launa F.; Webber, William D.

2005-03-01

This document presents the results of groundwater and vadose zone monitoring for fiscal year 2004 (October 2003 through September 2004)on the U.S. Department of Energy's Hanford Site in southeast Washington State.

Outline of the safety research results, in the power reactor field, fiscal year 1996

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-11-01

The Power Reactor and Nuclear Fuel Development Corporation (PNC) has promoted the safety research in fiscal year of 1996 according to the Fundamental Research on Safety Research (fiscal year 1996 to 2000) prepared on March, 1996. Here is described on the research results in fiscal year 1996, the first year of the 5 years programme, and whole outline of the fundamental research on safety research, on the power reactor field (whole problems on the new nuclear converter and the fast breeder reactor field and problems relating to the power reactor in the safety for earthquake and probability theoretical safety evaluation field). (G.K.)

Animal intrusion status report for fiscal year 1990

International Nuclear Information System (INIS)

Landeen, D.S.

1991-03-01

The Protective Barrier and Warning Marker System Development Plan identified tasks that need to be completed to design a final protective barrier to implement in-place disposal of radioactive waste. This report summarizes the animal intrusion work conducted by Westinghouse Hanford Company in fiscal year 1990 regarding small mammals and water infiltration. An animal intrusion lysimeter facility was constructed and installed in fiscal year 1988. The facility consists of two outer boxes buried at grade that serve as receptacles for six animal intrusion lysimeters. Small burrowing mammals common to the Hanford Site environs are introduced over a 3- to 4-month period. Supplemental precipitation is added to three of the lysimeters with a rainulator at a rate equivalent to a 100-year storm. Soil moisture samples are taken before and after each test, and soil moisture measurements are also taken with a hydroprobe during the test period. During fiscal year 1990, tests three and four were completed and test five was initiated. Results of test three (summer treatment), which used Townsend ground squirrels and pocket gophers, indicated that the additional 1.5 inches of precipitation that was added with the rainulator was lost during this test. The plots that did not receive any additional precipitation all lost water (5 to 6 percent). Results from test four (winter treatment), which used pocket gophers and pocket mice, indicated that all of the lysimeters except one gained water. The two control lysimeters (rainulator plots and nonrainulator lysimeters with no animals) gained more water than their corresponding animal burrow lysimeters. 4 refs., 9 figs., 3 tabs

Rip currents, mega-cusps, and eroding dunes

Science.gov (United States)

Thornton, E.B.; MacMahan, J.; Sallenger, A.H.

2007-01-01

Dune erosion is shown to occur at the embayment of beach mega-cusps O(200 m alongshore) that are associated with rip currents. The beach is the narrowest at the embayment of the mega-cusps allowing the swash of large storm waves coincident with high tides to reach the toe of the dune, to undercut the dune and to cause dune erosion. Field measurements of dune, beach, and rip current morphology are acquired along an 18 km shoreline in southern Monterey Bay, California. This section of the bay consists of a sandy shoreline backed by extensive dunes, rising to heights exceeding 40 m. There is a large increase in wave height going from small wave heights in the shadow of a headland, to the center of the bay where convergence of waves owing to refraction over the Monterey Bay submarine canyon results in larger wave heights. The large alongshore gradient in wave height results in a concomitant alongshore gradient in morphodynamic scale. The strongly refracted waves and narrow bay aperture result in near normal wave incidence, resulting in well-developed, persistent rip currents along the entire shoreline. The alongshore variations of the cuspate shoreline are found significantly correlated with the alongshore variations in rip spacing at 95% confidence. The alongshore variations of the volume of dune erosion are found significantly correlated with alongshore variations of the cuspate shoreline at 95% confidence. Therefore, it is concluded the mega-cusps are associated with rip currents and that the location of dune erosion is associated with the embayment of the mega-cusp.

Solid Waste Program Fiscal Year 1996 Multi-Year Program Plan WBS 1.2.1, Revision 1

International Nuclear Information System (INIS)

1995-09-01

This document contains the Fiscal Year 1996 Multi-Year Program Plan for the Solid Waste Program at the Hanford Reservation in Richland, Washington. The Solid Waste Program treats, stores, and disposes of a wide variety of solid wastes consisting of radioactive, nonradioactive and hazardous material types. Solid waste types are typically classified as transuranic waste, low-level radioactive waste, low-level mixed waste, and non-radioactive hazardous waste. This report describes the mission, goals and program strategies for the Solid Waste Program for fiscal year 1996 and beyond

Solid Waste Program Fiscal Year 1996 Multi-Year Program Plan WBS 1.2.1, Revision 1

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-09-01

This document contains the Fiscal Year 1996 Multi-Year Program Plan for the Solid Waste Program at the Hanford Reservation in Richland, Washington. The Solid Waste Program treats, stores, and disposes of a wide variety of solid wastes consisting of radioactive, nonradioactive and hazardous material types. Solid waste types are typically classified as transuranic waste, low-level radioactive waste, low-level mixed waste, and non-radioactive hazardous waste. This report describes the mission, goals and program strategies for the Solid Waste Program for fiscal year 1996 and beyond.

29 CFR 403.1 - Fiscal year for reports required by this part.

Science.gov (United States)

2010-07-01

... 29 Labor 2 2010-07-01 2010-07-01 false Fiscal year for reports required by this part. 403.1 Section 403.1 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR LABOR-MANAGEMENT STANDARDS LABOR ORGANIZATION ANNUAL FINANCIAL REPORTS § 403.1 Fiscal year for reports required by this part. (a) As used in this...

Fiscal year 1995 final report for TTP SR-1320-04

International Nuclear Information System (INIS)

Cicero, C.A.; Bickford, D.F.; Marra, J.C.

1995-01-01

The purpose of this Technical Task Plan (TTP) in fiscal year 1995 was to develop vitrification technology for application to mercury and organic waste streams, which are considered problem streams for a large portion of the DOE complexes. In addition, efforts were continued for pilot-scale demonstrations on Rocky Flats Plant (RFP) Precipitate sludge, and Los Alamos National Laboratory (LANL) TA-50 sludge, which was a carry-over of fiscal year 1994 activities. Crucible-scale studies were performed on mercury and organic waste streams to determine the optimum glass compositions. The optimal compositions were then used to treat actual wastes on a bench-top scale. Reports were written to summarize the data and results from the mercury and organic studies. The pilot-scale studies with RFP and LANL simulated sludge used glass compositions determined in fiscal year 1994 studies. The pilot-scale studies were attempted in the EnVitCo cold-top melter and the Stir-Melter reg-sign stirred melter at the DOE/Industrial Center for Vitrification Research (Center)

Laboratory directed research development annual report. Fiscal year 1996

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-05-01

This document comprises Pacific Northwest National Laboratory`s report for Fiscal Year 1996 on research and development programs. The document contains 161 project summaries in 16 areas of research and development. The 16 areas of research and development reported on are: atmospheric sciences, biotechnology, chemical instrumentation and analysis, computer and information science, ecological science, electronics and sensors, health protection and dosimetry, hydrological and geologic sciences, marine sciences, materials science and engineering, molecular science, process science and engineering, risk and safety analysis, socio-technical systems analysis, statistics and applied mathematics, and thermal and energy systems. In addition, this report provides an overview of the research and development program, program management, program funding, and Fiscal Year 1997 projects.

Reducing the age range of tsunami deposits by 14C dating of rip-up clasts

Science.gov (United States)

Ishizawa, Takashi; Goto, Kazuhisa; Yokoyama, Yusuke; Miyairi, Yosuke; Sawada, Chikako; Takada, Keita

2018-02-01

Erosion by tsunami waves represents an important issue when determining the age of a tsunami deposit, because the age is usually estimated using dating of sediments above and below the deposit. Dating of material within the tsunami deposit, if suitable material is obtainable, can be used to further constrain its age. Eroded sediments are sometimes incorporated within the tsunami deposits as rip-up clasts, which might therefore be used as minimum age dating material. However, the single calibrated 14C age often shows a wide age range because of fluctuations in the calibration curve. Therefore, it remains uncertain whether rip-up clast measurements are useful to constrain the depositional age of tsunami deposits, or not. In this study, we carried out high-resolution 14C dating of tsunami deposits, including rip-up clasts of peat, in Rikuzentakata, northeastern Japan, where numerous rip-up clasts were observed within a tsunami deposit. Sediments above and below the tsunami deposit and a 5 cm large rip-up clast were dated sequentially. Comparison of these dating results with the calibration curve revealed that the clast was inverted. Its age was better constrained based on the stratigraphic order, and we infer that the clast corresponds to approximately 100 years of sedimentation. The oldest age of the clast was consistent with the age of the peat immediately below the tsunami deposit, suggesting that surface sediments probably formed the rip-up clast at the time of the tsunami. Thus, the dating of the rip-up clast was useful to further constrain the depositional age of the tsunami deposit, as we narrowed the tsunami deposit age range by approximately 100 years. Results show that ignoring tsunami-related erosion might lead to overestimation of the tsunami deposit age. For this reason, an appropriate dating site, which is less affected by minor tsunami-related erosion with regards to the paleo-topography, should be explored. We therefore propose a more effective

Hanford Site Groundwater Monitoring for Fiscal Year 2000

Energy Technology Data Exchange (ETDEWEB)

Hartman, Mary J.; Morasch, Launa F.; Webber, William D.

2001-03-01

This report presents the results of groundwater and vadose zone monitoring and remediation for fiscal year 2000 on the U.S. Department of Energy's Hanford Site, Washington. The most extensive contaminant plumes are tritium, iodine-129, and nitrate, which all had multiple sources and are very mobile in groundwater. Carbon tetrachloride and associated organic constituents form a relatively large plume beneath the central part of the Site. Hexavalent chromium is present in smaller plumes beneath the reactor areas along the river and beneath the central part of the site. Strontium-90 exceeds standards beneath each of the reactor areas, and technetium-99 and uranium are present in the 200 Areas. RCRA groundwater monitoring continued during fiscal year 2000. Vadose zone monitoring, characterization, remediation, and several technical demonstrations were conducted in fiscal year 2000. Soil gas monitoring at the 618-11 burial ground provided a preliminary indication of the location of tritium in the vadose zone and in groundwater. Groundwater modeling efforts focused on 1) identifying and characterizing major uncertainties in the current conceptual model and 2) performing a transient inverse calibration of the existing site-wide model. Specific model applications were conducted in support of the Hanford Site carbon tetrachloride Innovative Treatment Remediation Technology; to support the performance assessment of the Immobilized Low-Activity Waste Disposal Facility; and in development of the System Assessment Capability, which is intended to predict cumulative site-wide effects from all significant Hanford Site contaminants.

Report of joint utilization results in fiscal year 1994

International Nuclear Information System (INIS)

1995-01-01

Joint utilization seems to aim at the effective use of limited funds by concentrating facilities. There is a demerit that for doing experiment, it is necessary to take a trouble of going to the place. However by utilizing jointly one facility, there is the possibility of the occurrence of sympathizing phenomena directly connected to new ideas among researchers, and it is just the state joint utilization should be in. In fiscal year 1994, the Yayoi and the linac were put to joint utilization as expected, and many results of researches were obtained by the users. In this book, in addition to the report of the results of joint utilization, the report of the Yayoi research meetings held in fiscal year 1994 is included. Eight lectures on fast neutron science, the reports of joint utilization results of 15 Yayoi on-pile studies, 9 Yayoi off-pile studies and 16 linac studies, and the reports of 11 Yayoi research meetings are included in this book. The list of the events held in the Nuclear Engineering Research Laboratory, University of Tokyo, in fiscal year 1994, the list of the names of various committee members, and the list of the names of the persons in charge of joint utilization experiments are attached. (K.I.)

Nuclear fuels technologies fiscal year 1996 research and research development test results

International Nuclear Information System (INIS)

Beard, C.A.; Blair, H.T.; Buksa, J.J.; Butt, D.P.

1996-01-01

During fiscal year 1996, the Department of Energy's Office of Fissile Materials Disposition (OFMD) funded Los Alamos National Laboratory (LANL) to investigate issues associated with the fabrication of plutonium from dismantled weapons into mixed-oxide (MOX) nuclear fuel for disposition in nuclear power reactors. These issues can be divided into two main categories: issues associated with the fact that the plutonium from dismantled weapons contains gallium, and issues associated with the unique characteristics of the PuO 2 produced by the dry conversion process that OFMD is proposing to convert the weapons material. Initial descriptions of the experimental work performed in fiscal year 1996 to address these issues can be found in Nuclear Fuels Technologies Fiscal Year 1996 Research and Development Test Matrices'. However, in some instances the change in programmatic emphasis towards the Parallex program either altered the manner in which some of these experiments were performed (i.e., the work was done as part of the Parallex fabrication development and not as individual separate-effects tests as originally envisioned) or delayed the experiments into Fiscal Year 1997. This report reviews the experiments that were conducted and presents the results. 7 figs., 14 tabs

76 FR 55403 - Announcement of Funding Awards for Fiscal Year 2010 Transformation Initiative: Sustainable...

Science.gov (United States)

2011-09-07

... Awards for Fiscal Year 2010 Transformation Initiative: Sustainable Communities Research Grant (SCRGP... Fiscal Year (FY) 2010 Transformative Initiative: Sustainable Communities Research Grant Program (SCRGP...&R), under the Assistant Secretary, administered the FY10 Sustainable Communities Research Grant...

Outline of electric power facility plan in fiscal year 1988

International Nuclear Information System (INIS)

1988-01-01

As to the electric power facility plan in fiscal year 1988, 15 designated electric power enterprises made the notification to the Minister of International Trade and Industry in March, 1988. This outline of the facility plan summarized the plans of 66 enterprises in total, including the plans of municipally operated, joint thermal power and other enterprises in addition to the above 15. In order to ensure the stable supply of electric power, the Ministry of International Trade and Industry considers that it is indispensable to purposefully develop electric power sources and the facilities for distribution along this facility plan. The forecast for fiscal year 1997 is : total electric power demand 778.2 billion kWh, maximum power demand 151.21 million kW, and yearly load factor 56.9 %. This is equivalent to the yearly growth of 2.4 %. In fiscal year 1988, it is planned to present 29 plants of 2760 MW to the Power Source Development Coordination Council. The breakdown is : hydroelectricity 140 MW, thermal power 2010 MW, and nuclear power 610 MW. The Ministry guides electric power enterprises so as to realize the diversification of electric power sources. Also the increase of transmission and transformation facilities, the plan of equipment investment and others are reported. (Kako, I.)

Research and development program, fiscal year 1974

Energy Technology Data Exchange (ETDEWEB)

1972-04-01

The biomedical program of the Laboratory of Nuclear Medicine and Radiation Biology for Fiscal Year 1974 is conducted within the scope of the following categories: Effects of Radiation of Living Organisms; Molecular and Cellular Radiobiology; Land and Fresh Water Environmental Sciences; Radiological and Health Physics and Instrumentation; and Nuclear Medical Research. (ACR)

RIP3 Inhibits Inflammatory Hepatocarcinogenesis but Promotes Cholestasis by Controlling Caspase-8- and JNK-Dependent Compensatory Cell Proliferation

Directory of Open Access Journals (Sweden)

Mihael Vucur

2013-08-01

Full Text Available For years, the term “apoptosis” was used synonymously with programmed cell death. However, it was recently discovered that receptor interacting protein 3 (RIP3-dependent “necroptosis” represents an alternative programmed cell death pathway activated in many inflamed tissues. Here, we show in a genetic model of chronic hepatic inflammation that activation of RIP3 limits immune responses and compensatory proliferation of liver parenchymal cells (LPC by inhibiting Caspase-8-dependent activation of Jun-(N-terminal kinase in LPC and nonparenchymal liver cells. In this way, RIP3 inhibits intrahepatic tumor growth and impedes the Caspase-8-dependent establishment of specific chromosomal aberrations that mediate resistance to tumor-necrosis-factor-induced apoptosis and underlie hepatocarcinogenesis. Moreover, RIP3 promotes the development of jaundice and cholestasis, because its activation suppresses compensatory proliferation of cholangiocytes and hepatic stem cells. These findings demonstrate a function of RIP3 in regulating carcinogenesis and cholestasis. Controlling RIP3 or Caspase-8 might represent a chemopreventive or therapeutic strategy against hepatocellular carcinoma and biliary disease.

Japan's Fiscal Policy and Fiscal Reconstruction

OpenAIRE

Ihori, Toshihiro; Nakamoto, Atsushi

2005-01-01

This paper investigates the macroeconomic effects of fiscal policy and the fiscal reconstruction movement in Japan. We first summarize Japan's fiscal policy in recent years and discuss advantages and disadvantages of government deficits. Next, we investigate the macroeconomic effects of Japanese fiscal policy and evaluate the plausibility of non-Keynesian effects. We also analyze the possibility of the crowding-in effect of fiscal policy and investigate the spillover effects of deregulation. ...

Fiscal Year 2009 Revegetation Assessment

Energy Technology Data Exchange (ETDEWEB)

Michael Lewis

2009-10-01

This report summarizes the Fiscal Year 2009 Revegetation Assessment by Battelle Energy Alliance, LLC. This assessment was conducted to supplement documentation related to the Storm Water Pollution Prevention Plan for Construction Activities and to ensure that disturbed vegetation and soil at various locations are being restored. This report provides the following information for each site being monitored by the Idaho National Laboratory Environmental Support and Services: • Summary of each site • Assessment of vegetation status and site stabilization at each location • Recommendation(s) for each site.

Fiscal Year 2010 Revegetation Assessment

Energy Technology Data Exchange (ETDEWEB)

Jenifer Nordstrom; Mike Lewis

2010-11-01

This report summarizes the Fiscal Year 2010 Revegetation Assessment by Battelle Energy Alliance, LLC. This assessment was conducted to supplement documentation related to the Storm Water Pollution Prevention Plan for Construction Activities and to ensure that disturbed vegetation and soil at various locations are being restored. This report provides the following information for each site being monitored by the Idaho National Laboratory Environmental Support and Services: • Summary of each site • Assessment of vegetation status and site stabilization at each location • Recommendation(s) for each site.

Science to Support DOE Site Cleanup: The Pacific Northwest National Laboratory Environmental Management Science Program Awards - Fiscal Year 2000 Mid-Year Progress Report

International Nuclear Information System (INIS)

CD Carlson; SQ Bennett

2000-01-01

Pacific Northwest National Laboratory was awarded ten Environmental Management Science Program (EMSP) research grants in fiscal year 1996, six in fiscal year 1997, eight in fiscal year 1998, and seven in fiscal year 1999. All of the fiscal year 1996 award projects have been completed and will publish final reports, so their annual updates will not be included in this document. This section summarizes how each of the currently funded grants addresses significant US Department of Energy (DOE) cleanup issues, including those at the Hanford Site. The technical progress made to date in each of these research projects is addressed in more detail in the individual progress reports contained in this document. This research performed at PNNL is focused primarily in four areas: Tank Waste Remediation; Decontamination and Decommissioning; Spent Nuclear Fuel and Nuclear Materials; and Soil and Groundwater Cleanup

Science to Support DOE Site Cleanup: The Pacific Northwest National Laboratory Environmental Management Science Program Awards - Fiscal Year 2000 Mid-Year Progress Report

Energy Technology Data Exchange (ETDEWEB)

Carlson, Clark D.; Bennett, Sheila Q.

2000-07-25

Pacific Northwest National Laboratory was awarded ten Environmental Management Science Program (EMSP) research grants in fiscal year 1996, six in fiscal year 1997, eight in fiscal year 1998 and seven in fiscal year 1999.(a) All of the fiscal year 1996 awards have been completed and the Principal Investigators are writing final reports, so their summaries will not be included in this document. This section summarizes how each of the currently funded grants addresses significant U.S. Department of Energy (DOE) cleanup issues, including those at the Hanford Site. The technical progress made to date in each of these research projects is addressed in more detail in the individual progress reports contained in this document. This research performed at PNNL is focused primarily in four areas: Tank Waste Remediation, Decontamination and Decommissioning, Spent Nuclear Fuel and Nuclear Materials, and Soil and Groundwater Cleanup.

Science to Support DOE Site Cleanup: The Pacific Northwest National Laboratory Environmental Management Science Program Awards - Fiscal Year 2000 Mid-Year Progress Report

Energy Technology Data Exchange (ETDEWEB)

CD Carlson; SQ Bennett

2000-07-25

Pacific Northwest National Laboratory was awarded ten Environmental Management Science Program (EMSP) research grants in fiscal year 1996, six in fiscal year 1997, eight in fiscal year 1998, and seven in fiscal year 1999. All of the fiscal year 1996 award projects have been completed and will publish final reports, so their annual updates will not be included in this document. This section summarizes how each of the currently funded grants addresses significant US Department of Energy (DOE) cleanup issues, including those at the Hanford Site. The technical progress made to date in each of these research projects is addressed in more detail in the individual progress reports contained in this document. This research performed at PNNL is focused primarily in four areas: Tank Waste Remediation; Decontamination and Decommissioning; Spent Nuclear Fuel and Nuclear Materials; and Soil and Groundwater Cleanup.

78 FR 1301 - Fiscal Year 2012 Public Transportation on Indian Reservations Program Project Selections

Science.gov (United States)

2013-01-08

... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Fiscal Year 2012 Public Transportation... Affairs (BIA) in the U.S. Department of the Interior for public transportation. An additional $500,000 is... Fiscal Year 2013 Public Transportation on Indian Reservations Program, which: (1) Introduces FTA's...

Hanford Site Groundwater Monitoring for Fiscal Year 1999

Energy Technology Data Exchange (ETDEWEB)

MJ Hartman; LF Morasch; WD Webber

2000-05-10

This report presents the results of groundwater and vadose zone monitoring and remediation for fiscal year 1999 on the US. Department of Energy's Hanford Site, Washington. Water-level monitoring was performed to evaluate groundwater flow directions, to track changes in water levels, and to relate such changes to evolving disposal practices. Measurements for site-wide maps were conducted in June in past years and are now measured in March to reflect conditions that are closer to average. Water levels over most of the Hanford Site continued to decline between June 1998 and March 1999. The most widespread radiological contaminant plumes in groundwater were tritium and iodine-129. Concentrations of carbon-14, strontium-90, technetium-99, and uranium also exceeded drinking water standards in smaller plumes. Cesium-137 and plutonium exceeded standards only near the 216-B-5 injection well. Derived concentration guide levels specified in US Department of Energy Order 5400.5 were exceeded for plutonium, strontium-90, tritium, and uranium in small plumes or single wells. Nitrate and carbon tetrachloride are the most extensive chemical contaminants. Chloroform, chromium, cis-1,2dichloroethylene, cyanide, fluoride, and trichloroethylene also were present in smaller areas at levels above their maximum contaminant levels. Metals such as aluminum, cadmium, iron, manganese, and nickel exceeded their maximum contaminant levels in filtered samples from numerous wells; however, in most cases, they are believed to represent natural components of groundwater. ''Resource Conservation and Recovery Act of 1976'' groundwater monitoring continued at 25 waste management areas during fiscal year 1999: 16 under detection programs and data indicate that they are not adversely affecting groundwater; 6 under interim status groundwater quality assessment programs to assess contamination; and 2 under final status corrective-action programs. Another site, the 120-D-1 ponds

Environmental Molecular Sciences Laboratory Annual Report: Fiscal Year 2006

Energy Technology Data Exchange (ETDEWEB)

Foster, Nancy S.; Showalter, Mary Ann

2007-03-23

This report describes the activities and research performed at the Environmental Molecular Sciences Laboratory, a Department of Energy national scientific user facility at Pacific Northwest National Laboratory, during Fiscal Year 2006.

State Library Agency Survey: Fiscal Year 2008

Science.gov (United States)

Henderson, Everett; Miller, Kim; Farrell, Michele; Brock, Faye; Dorinski, Suzanne; Freeman, Michael; Frid, Lisa; Hardesty, Laura; Music, Christopher; O'Shea, Patricia; Sheckells, Cindy

2009-01-01

This report marks the third release of library statistics data from the Institute of Museum and Library Services (IMLS). It contains data on state library agencies in the 50 states and the District of Columbia for state fiscal year (FY) 2008. The data were collected through the State Library Agencies (StLA) Survey, the product of a cooperative…

Solar Program Overview: Fiscal Years 2002& 2003 (Brochure)

Energy Technology Data Exchange (ETDEWEB)

2004-06-01

This document describes the research activities and accomplishments of the DOE Solar Energy Technologies Program for fiscal years 2002 and 2003. It includes detailed accounts, charts, and photos of R&D activities in the areas of photovoltaics, concentrating solar power, and solar heating and lighting

Naval Petroleum and Oil Shale Reserves. Annual report of operations, Fiscal year 1992

Energy Technology Data Exchange (ETDEWEB)

1992-12-31

During fiscal year 1992, the reserves generated $473 million in revenues, a $181 million decrease from the fiscal year 1991 revenues, primarily due to significant decreases in oil and natural gas prices. Total costs were $200 million, resulting in net cash flow of $273 million, compared with $454 million in fiscal year 1991. From 1976 through fiscal year 1992, the Naval Petroleum and Oil Shale Reserves generated more than $15 billion in revenues and a net operating income after costs of $12.5 billion. In fiscal year 1992, production at the Naval Petroleum Reserves at maximum efficient rates yielded 26 million barrels of crude oil, 119 billion cubic feet of natural gas, and 164 million gallons of natural gas liquids. From April to November 1992, senior managers from the Naval Petroleum and Oil Shale Reserves held a series of three workshops in Boulder, Colorado, in order to build a comprehensive Strategic Plan as required by Secretary of Energy Notice 25A-91. Other highlights are presented for the following: Naval Petroleum Reserve No. 1--production achievements, crude oil shipments to the strategic petroleum reserve, horizontal drilling, shallow oil zone gas injection project, environment and safety, and vanpool program; Naval Petroleum Reserve No. 2--new management and operating contractor and exploration drilling; Naval Petroleum Reserve No. 3--steamflood; Naval Oil Shale Reserves--protection program; and Tiger Team environmental assessment of the Naval Petroleum and Oil Shale Reserves in Colorado, Utah, and Wyoming.

Dark energy, wormholes, and the big rip

International Nuclear Information System (INIS)

Faraoni, V.; Israel, W.

2005-01-01

The time evolution of a wormhole in a Friedmann universe approaching the big rip is studied. The wormhole is modeled by a thin spherical shell accreting the superquintessence fluid--two different models are presented. Contrary to recent claims that the wormhole overtakes the expansion of the universe and engulfs it before the big rip is reached, it is found that the wormhole becomes asymptotically comoving with the cosmic fluid and the future evolution of the universe is fully causal

Analysis of Block OMP using Block RIP

OpenAIRE

Wang, Jun; Li, Gang; Zhang, Hao; Wang, Xiqin

2011-01-01

Orthogonal matching pursuit (OMP) is a canonical greedy algorithm for sparse signal reconstruction. When the signal of interest is block sparse, i.e., it has nonzero coefficients occurring in clusters, the block version of OMP algorithm (i.e., Block OMP) outperforms the conventional OMP. In this paper, we demonstrate that a new notion of block restricted isometry property (Block RIP), which is less stringent than standard restricted isometry property (RIP), can be used for a very straightforw...

Annual report of operation management in nuclear power stations, fiscal year 1985

International Nuclear Information System (INIS)

1986-09-01

Twenty years have elapsed since the first practical nuclear reactor in Japan started the operation. In the generated power in fiscal year 1985, that of nuclear power stations for the first time overtook that of thermal power stations, and now the age of nuclear power as the main and oil power as the subordinate has begun. As of the end of fiscal year 1985, there were 32 nuclear power plants in operation, having total output capacity of 24.521 million kW. In fiscal year 1985, nuclear power plants generated about 159 billion kWh, which is about 26 % of electric power supply. As to the capacity factor, 76 % was attained in fiscal year 1985, and this is ranked in the top group of LWR-operating countries in the world. It showed that the Japanese technology of nuclear power generation is at the top level in the world. However, in order to increase nuclear power generation and to accomplish the role of main electric power source hereafter, it is necessary to further increase the reliability and economical efficiency. The list of nuclear power stations in Japan, the state of operation of nuclear power stations, the state of accidents and troubles, the state of regular inspection, the management of radioactive wastes and the radiation exposure of workers in nuclear power stations, the operational management and others are reported. (Kako, I.)

Nuclear test-experimental science annual report, Fiscal year 1990

International Nuclear Information System (INIS)

Struble, G.L.; Middleton, C.; Anderson, S.E.; Cherniak, J.; Donohue, M.L.; Francke, A.; Hedman, I.; Kirvel, R.D.

1991-01-01

Fiscal year 1990 was another year of outstanding accomplishments for the Nuclear Test-Experimental Science (NTES) Program at Lawrence Livermore National Laboratory (LLNL). We continued to make progress to enhance the experimental science in the Weapons Program and to improve the operational efficiency and productivity of the Nuclear Test Program

AVST Morphing Project Research Summaries in Fiscal Year 2001

Science.gov (United States)

McGowan, Anna-Maria R.

2002-01-01

The Morphing project at the National Aeronautics and Space Agency's Langley Research Center is part of the Aerospace Vehicle Systems Program Office that conducts fundamental research on advanced technologies for future flight vehicles. The objectives of the Morphing project are to develop and assess advanced technologies and integrated component concepts to enable efficient, multi-point adaptability in air and space vehicles. In the context of the project, the word "morphing" is defined as "efficient, multi-point adaptability" and may include micro or macro, structural or fluidic approaches. The current document on the Morphing project is a compilation of research summaries and other information on the project from fiscal year 2001. The focus of this document is to provide a brief overview of the project content, technical results and lessons learned from fiscal year 2001.

Department of Defense Agency Financial Report. Fiscal Year 2007

National Research Council Canada - National Science Library

2007-01-01

The Department of Defense (DoD) Fiscal Year (FY) 2007 Agency Financial Report (AFR) provides the President, the Congress, other Federal departments and agencies, and the American public an overview of the Department's financial condition...

Multiple roles for nuclear localization signal (NLS, aa 442-472) of receptor interacting protein 3 (RIP3)

International Nuclear Information System (INIS)

Li Mei; Feng Shanshan; Wu Mian

2008-01-01

RIP3, a Ser/Thr kinase of RIP (Receptor Interacting Protein) family, is recruited to the TNFR1 signaling complex through RIP and has been shown to mediate apoptosis induction and NF-κB activation. RIP3 is a nucleocytoplasmic shuttling protein and its unconventional nuclear localization signal (NLS, 442-472 aa) is sufficient to trigger apoptosis in the nucleus. In this study, we demonstrate that this NLS exhibits several other roles besides apoptotic function. Firstly, this NLS was found to be required for both RIP3-induced apoptosis and RIP3-mediated NF-κB activation. Next, similar to RHIM motif (RIP homotypic interaction motif), NLS of RIP3 was found to be involved in RIP3-RIP interaction. Furthermore, this NLS was found to be both sufficient and necessary for RIP3 self-association. Our primary data also showed that RIP3 might form a homodimer within cells, and its apoptotic activity may not be required for this dimerization, rather the intactness of NLS determines RIP3-induced apoptosis, since a point mutation at amino acid residue 452 (Ile to Ala) within NLS greatly reduced its apoptotic ability, despite that RIP3 point mutant RIP3/I452A is able to dimerize with wild type RIP3 or itself

75 FR 59282 - Notice of Availability: Notice of Funding Availability (NOFA) for Fiscal Year (FY) 2010 Continuum...

Science.gov (United States)

2010-09-27

... and the HUD's Fiscal Year 2010 Notice of Funding Availability (NOFA) Policy Requirements and General...: Notice of Funding Availability (NOFA) for Fiscal Year (FY) 2010 Continuum of Care (CoC) Homeless... (Pub. L. 111-117, approved December 16, 2009). Carried over or recaptured funds from previous fiscal...

Fiscal year 1990 Rocky Flats Plant environmental restoration program current-year work plan

International Nuclear Information System (INIS)

Nielsen, T.; Waage, E.; Miller, D.

1990-01-01

This paper reports on the FY90 Current Year Work Plan (CYWP), intended to serve as a guiding document with which the Environmental Restoration and RCRA Compliance programs will be implemented at the Rocky Flats Plant, The Current Year Work Plan document serves to provide in one single document any cross-references necessary to understand how the DOE Five Year Plan, Site Specific Plan, or any other related documents fit into the Current Year Work Plan for the Rocky Flats Environmental Restoration. The scope of this paper will compare the planned Fiscal Year 1990 environmental restoration activities to those actually achieved at the end of the fiscal year. The DOE Headquarters (HQ) issued the Environmental Restoration and Waste Management (ER/WM) Five-Year Plan (FYP). The purpose of the FYP is to establish an agenda for compliance and cleanup against which progress will be measured. The Five Year Plan has been updated to include the Colorado Department of Health (CDH), Evironmental Protection Agency (EPA), and Department of Energy (DOE) Inter Agency Agreement Environmental Restoration activities. It addresses hazardous wastes, radioactive wastes, mixed wastes (radioactive and hazardous), and sanitary wastes. It also addresses facilities and sites contaminated with or used in the management of those wastes

Bohmian quantization of the big rip

International Nuclear Information System (INIS)

Pinto-Neto, Nelson; Pantoja, Diego Moraes

2009-01-01

It is shown in this paper that minisuperspace quantization of homogeneous and isotropic geometries with phantom scalar fields, when examined in the light of the Bohm-de Broglie interpretation of quantum mechanics, does not eliminate, in general, the classical big rip singularity present in the classical model. For some values of the Hamilton-Jacobi separation constant present in a class of quantum state solutions of the Wheeler-De Witt equation, the big rip can be either completely eliminated or may still constitute a future attractor for all expanding solutions. This is contrary to the conclusion presented in [M. P. Dabrowski, C. Kiefer, and B. Sandhofer, Phys. Rev. D 74, 044022 (2006).], using a different interpretation of the wave function, where the big rip singularity is completely eliminated ('smoothed out') through quantization, independently of such a separation constant and for all members of the above mentioned class of solutions. This is an example of the very peculiar situation where different interpretations of the same quantum state of a system are predicting different physical facts, instead of just giving different descriptions of the same observable facts: in fact, there is nothing more observable than the fate of the whole Universe.

Summary and Analysis of President Obama's Education Budget Request, Fiscal Year 2012: Issue Brief

Science.gov (United States)

New America Foundation, 2011

2011-01-01

President Barack Obama submitted his third budget request to Congress on February 14th, 2011. The detailed budget request includes proposed funding levels for federal programs and agencies in aggregate for the upcoming 10 fiscal years, and specific fiscal year 2012 funding levels for individual programs subject to appropriations. Congress will use…

Environmental support FY 1995 multi-year program plan/fiscal year work plan WBS 1.5.2/7.4.11

International Nuclear Information System (INIS)

Moore, D.A.

1994-09-01

The multi-Year Program Plan (MYPP) is the programmatic planning baseline document for technical, schedule, and cost data. The MYPP contains data by which all work is managed, performed and controlled. The integrated planning process, defined by RL, is redicted on establishment of detailed data in the MYPP. The MYPP includes detailed information for the data elements including Level II critical path schedules, cost estimate detail, and updated technical data to be done annually. There will be baseline execution year and out year approval with work authorization for execution. The MYPP will concentrate on definition of the scope, schedule, cost and program element level critical path schedules that show the relationship of planned activities. The Fiscal Year Work Plan (FYWP) is prepared for each program to provide the basis for authorizing fiscal year work. The MYPP/FYWP will be structured into three main areas: (1) Program Overview; (2) Program Baselines; (3) Fiscal Year Work Plan

RIP2: A novel player in the regulation of keratinocyte proliferation and cutaneous wound repair?

International Nuclear Information System (INIS)

Adams, Stephanie; Valchanova, Ralitsa S.; Munz, Barbara

2010-01-01

We could recently demonstrate an important role of receptor interacting protein 4 (RIP4) in the regulation of keratinocyte differentiation. Now, we analyzed a potential role of the RIP4 homolog RIP2 in keratinocytes. Specifically, we demonstrate here that rip2 expression is induced by scratch-wounding and after the induction of differentiation in these cells. Furthermore, serum growth factors and cytokines can induce rip2, with TNF-α-dependent induction being dependent on p38 MAPK. In addition, we demonstrate that scratch-induced upregulation of rip2 expression is completely blocked by the steroid dexamethasone. Since we also show that RIP2 is an important player in the regulation of keratinocyte proliferation, these data suggest that inhibition of rip2 upregulation after wounding might contribute to the reduced and delayed wound re-epithelialization phenotype seen in glucocorticoid-treated patients.

Engineering Technical Support Center Annual Report Fiscal Year 2016

Science.gov (United States)

This report highlights significant projects that the ETSC supported in fiscal year 2016. These projects have addressed an array of environmental scenarios, including, but not limited to remote mining contamination, expansive landfill waste, cumulative impacts from multiple contam...

A summary report on researches carried out by post-doctoral fellows on fiscal year 2001

International Nuclear Information System (INIS)

2002-07-01

The Japan Nuclear Cycle Development Institute (JNC) introduced the post-doctoral fellows system since fiscal year 1997, to intend to promote talents encouragement by supplying researching environments to young researchers with scholarship of doctor. This system aims not only to independently promote his own research theme certified by JNC by a young researcher with rich initiatives within a period of two or three years to obtain business as a researcher, but also to effectively progress a researching business of JNC. This report contains summaries on 17 items researching results on fiscal year 2001, of which 6 items are finished on this fiscal year. (G.K.)

Computer optimization of cutting yield from multiple ripped boards

Science.gov (United States)

A.R. Stern; K.A. McDonald

1978-01-01

RIPYLD is a computer program that optimizes the cutting yield from multiple-ripped boards. Decisions are based on automatically collected defect information, cutting bill requirements, and sawing variables. The yield of clear cuttings from a board is calculated for every possible permutation of specified rip widths and both the maximum and minimum percent yield...

"I didn't know her, but…": parasocial mourning of mediated deaths on Facebook RIP pages

Science.gov (United States)

Klastrup, Lisbeth

2015-04-01

This article examines the use of six Danish "Rest in Peace" or (RIP) memorial pages. The article focuses on the relation between news media and RIP page use, in relation to general communicative practices on these pages. Based on an analysis of press coverage of the deaths of six young people and a close analysis of 1,015 comments extracted from the RIP pages created to memorialize them, it is shown that their deaths attracted considerable media attention, as did the RIP pages themselves. Comment activity seem to reflect the news stories in the way the commenters refer to the context of death and the emotional distress they experience, but mainly comments on the RIP pages are conventional expressions of sympathy and "RIP" wishes. The article concludes that public RIP pages might be understood as virtual spontaneous shrines, affording an emerging practice of "RIP-ing."

Hanford Site Groundwater Monitoring for Fiscal Year 2002

Energy Technology Data Exchange (ETDEWEB)

Hartman, Mary J.; Morasch, Launa F.; Webber, William D.

2003-02-28

This report presents the results of groundwater and vadose zone monitoring and remediation for fiscal year 2002 on the U.S. Department of Energy's Hanford Site in Washington State. This report is written to meet the requirements in CERCLA, RCRA, the Atomic Energy Act of 1954, and Washington State Administrative Code.

Rip Currents, Mega-Cusps, and Eroding Dunes

OpenAIRE

Thornton, E.B.; MacMahan, J.; Sallenger, A.H.

2006-01-01

Submitted to Marine Geology 1 November 2006 Dune erosion is shown to occur at the embayment of beach mega-cusps O(200m alongshore) that are associated with rip currents. The beach is the narrowest at the embayment of the mega-cusps allowing the swash of large storm waves coincident with high tides to reach the toe of the dune, to undercut the dune and to cause dune erosion. Field measurements of dune, beach, and rip current morphology are acquired along an 18 km shoreline in southern Mont...

77 FR 16251 - Announcement of Funding Awards, HOPE VI Revitalization Grant Program, Fiscal Year 2010

Science.gov (United States)

2012-03-20

... Awards, HOPE VI Revitalization Grant Program, Fiscal Year 2010 AGENCY: Office of the Assistant Secretary... the Fiscal Year 2010 (FY2010) Notice of Funding Availability (NOFA) for the HOPE VI Revitalization... recipients under the HOPE VI Revitalization grant program. FOR FURTHER INFORMATION CONTACT: For questions...

75 FR 64710 - Availability of the Fiscal Year 2009 Department of Defense Services Contracts Inventory

Science.gov (United States)

2010-10-20

... DEPARTMENT OF DEFENSE Office of the Secretary Availability of the Fiscal Year 2009 Department of... National Defense Authorization Act for Fiscal Year 2008 (NDAA 08) section 807, the Office of the Director, Defense Procurement and Acquisition Policy, Office of Program Acquisition and Strategic Sourcing (DPAP...

McKenzie River Focus Watershed Coordination: Fiscal Year 1998.

Energy Technology Data Exchange (ETDEWEB)

Runyon, John; Davis-Born, Renee

1998-01-01

This report summarizes accomplishments made by the McKenzie River Focus Watershed Council in the areas of coordination and administration during Fiscal Year 1998. Coordination and administration consists of tasks associated with Focus Watershed Council staffing, project management, and public outreach.

The Budget and Economic Outlook: Fiscal Years 2003-2012

National Research Council Canada - National Science Library

Crippen, Dan

2002-01-01

.... It satisfies the requirement of section 202(e) of the Congressional Budget Act of 1974 for CBO to submit to the Committees on the Budget periodic reports about fiscal policy and to provide five-year baseline projections of the federal budget...

EMSL Quarterly Highlights Report: 1st Quarter, Fiscal Year 2009

Energy Technology Data Exchange (ETDEWEB)

Showalter, Mary Ann; Kathmann, Loel E.; Manke, Kristin L.

2009-02-02

The EMSL Quarterly Highlights Report covers the science, staff and user recognition, and publication activities that occurred during the 1st quarter (October 2008 - December 2008) of Fiscal Year 2009.

History in Fiction:The Case of “Rip Van Winkle”%History in Fiction: The Case of “Rip Van Winkle”

Institute of Scientific and Technical Information of China (English)

Liu Jun

2009-01-01

Washington Irving's "Rip Van Winkle" has been so ritualistically cited and discussed by historians,political scientists and literary scholars that it is no longer just a simple tale but a prominent text in American culture.The tale,as one critic proclaims,"presides over the birth of the American imagination" (Fiedler xx).This essay revisits "Rip Van Winkle" for the sole purpose of considering how this literary text can also stimulate critical thinking on the connection between fiction (or poetry) and history.

The Budget and Economic Outlook: Fiscal Years 2001-2010

National Research Council Canada - National Science Library

2000-01-01

.... It satisfies the requirement of section 202(e) of the Congressional Budget Act of 1974 for CBO to submit periodic reports to the Committees on the Budget with respect to fiscal policy and to provide five-year baseline projections of the federal budget...

Annual report, fiscal year 1974-1975

International Nuclear Information System (INIS)

1976-01-01

This report presents the activities of the Philippine Atomic Energy Commission for fiscal year 1974-1975. Most of these activities in which the Commission was engaged were tied up to the national nuclear power development program and the development of a technique for uranium prospecting as well as assessing uranium deposits. A five-year program was also drawn up which was approved by the office of the President. The program component consisted largely of nuclear power development, preservation of the environment and basic science research. Also during the period under report, the Commission assumed the role of a human resources bank from which experts were drawn not only by other Government agencies but also foreign organizations

Hanford Site Groundwater Monitoring for Fiscal Year 2003

Energy Technology Data Exchange (ETDEWEB)

Hartman, Mary J.; Morasch, Launa F.; Webber, William D.

2004-04-12

This report presents the results of groundwater and vadose zone monitoring and remediation for fiscal year 2003 (October 2002 through September 2003) on the U.S. Department of Energy's Hanford Site, Washington. The most extensive contaminant plumes in groundwater are tritium, iodine-129, and nitrate, which all had multiple sources and are very mobile in groundwater. The largest portions of these plumes are migrating from the central Hanford Site to the southeast, toward the Columbia River. Concentrations of tritium, nitrate, and some other contaminants continued to exceed drinking water standards in groundwater discharging to the river in some locations. However, contaminant concentrations in river water remained low and were far below standards. Carbon tetrachloride and associated organic constituents form a relatively large plume beneath the central part of the Hanford Site. Hexavalent chromium is present in smaller plumes beneath the reactor areas along the river and beneath the central part of the site. Strontium-90 exceeds standards beneath all but one of the reactor areas, and technetium-99 and uranium are present in the 200 Areas. Uranium exceeds standards in the 300 Area in the south part of the Hanford Site. Minor contaminant plumes with concentrations greater than standards include carbon-14, cesium-137, cis-1,2-dichloroethene, cyanide, fluoride, plutonium, and trichloroethene. Monitoring for the ''Comprehensive Environmental Response, Compensation, and Liability Act'' is conducted in 11 groundwater operable units. The purpose of this monitoring is to define and track plumes and to monitor the effectiveness of interim remedial actions. Interim groundwater remediation in the 100 Areas continued with the goal of reducing the amount of chromium (100-K, 100-D, and 100-H) and strontium-90 (100-N) reaching the Columbia River. The objective of two interim remediation systems in the 200 West Area is to prevent the spread of carbon

Field test plan: Buried waste technologies, Fiscal Year 1995

International Nuclear Information System (INIS)

Heard, R.E.; Hyde, R.A.; Engleman, V.S.; Evans, J.D.; Jackson, T.W.

1995-06-01

The US Department of Energy, Office of Technology Development, supports the applied research, development, demonstration, testing, and evaluation of a suite of advanced technologies that, when integrated with commercially available baseline technologies, form a comprehensive remediation system for the effective and efficient remediation of buried waste. The Fiscal Year 1995 effort is to deploy and test multiple technologies from four functional areas of buried waste remediation: site characterization, waste characterization, retrieval, and treatment. This document is the basic operational planning document for the deployment and testing of the technologies that support the field testing in Fiscal Year 1995. Discussed in this document are the scope of the tests; purpose and objective of the tests; organization and responsibilities; contingency plans; sequence of activities; sampling and data collection; document control; analytical methods; data reduction, validation, and verification; quality assurance; equipment and instruments; facilities and utilities; health and safety; residuals management; and regulatory management

Environmental Information System Baden-Wuerttemberg, RIPS 2016. Spatial information and planning system; Umweltinformationssystem Baden-Wuerttemberg. Konzeption RIPS 2016. Raeumliches Informations- und Planungssystem

Energy Technology Data Exchange (ETDEWEB)

Weissenbach, Kurt; Czommer, Olaf; Ellmenreich, Bastian (eds.)

2016-04-21

The Spatial Information and Planning System (RIPS), as the overarching component of the Environmental Information System Baden-Wuerttemberg (UIS BW), implements the environmental and nature conservation-specific geoinformation-related requirements taking into account applicable framework conditions. To this end, RIPS offers tailor-made services on the basis of a standardized and in transnational cooperation developed technical kit for the areas of geodata processing and management as well as the development and provision of software components with geo-functions and geodata services as part of the technical and information procedures. The coordination and steering takes place via project development offices, working groups and committees in close coordination with the departments of environmental and nature conservation administration as well as further cooperation and in coordination with other specialist administrations. Taking into account changed framework conditions and new geo-referenced requirements in UIS BW, the present RIPS concept focuses on future-oriented geofunction and geodata management in the field of environmental and nature conservation management as well as the provision of geo-specialized environmental and nature conservation data for policy makers, administrators and the public on innovative technologies Applications and Services. [German] Das Raeumliche Informations- und Planungssystem (RIPS) setzt als uebergreifende Komponente des Umweltinformationssystems Baden-Wuerttemberg (UIS BW) die umwelt- und naturschutzspezifischen geoinformationsbezogenen Anforderungen unter Beruecksichtigung geltender Rahmenbedingungen um. Hierzu bietet RIPS massgeschneiderte Dienstleistungen auf der Basis eines standardisierten und in laenderuebergreifenden Kooperationen entwickelten technischen Baukastens fuer die Bereiche Geodatenverarbeitung und -management sowie die Entwicklung und Bereitstellung von Softwarekomponenten mit Geofunktionen und Geodatendiensten

Atomic safety and licensing board panel: Annual report, Fiscal Year 1988

International Nuclear Information System (INIS)

1989-03-01

This is the fiscal year 1988 annual report of the Atomic Safety and Licensing Board Panel. In response to further reduction in is authorized staffing level and with an eye toward the proposed full- text, electronic docket of the expected High-Level Waste Repository proceedings, the Panel stepped up efforts during fiscal year 1988 to extend the scope, depth and availability of its Computer Assistance Project (CAP) through INQUIRE. INQUIRE, and the Panel's ability to use the system to expeditiously manage and search the massive records that characterize our most complex cases, has generated great interest among legal practitioners and adjudicatory bodies throughout the United States and Canada

Field Observations of Surf Zone-Inner Shelf Exchange on a Rip-Channeled Beach

NARCIS (Netherlands)

Brown, J.A.; MacMahan, J.H.; Reniers, A.J.H.M.; Thornton, E.B.

2015-01-01

Cross-shore exchange between the surf zone and the inner shelf is investigated using Lagrangian and Eulerian field measurements of rip current flows on a rip-channeled beach in Sand City, California. Surface drifters released on the inner shelf during weak wind conditions moved seaward due to rip

A Role of RIP3-Mediated Macrophage Necrosis in Atherosclerosis Development

OpenAIRE

Lin, Juan; Li, Hanjie; Yang, Min; Ren, Junming; Huang, Zhe; Han, Felicia; Huang, Jian; Ma, Jianhui; Zhang, Duanwu; Zhang, Zhirong; Wu, Jianfeng; Huang, Deli; Qiao, Muzhen; Jin, Guanghui; Wu, Qiao

2013-01-01

Necrotic death of macrophages has long been known to be present in atherosclerotic lesions but has not been studied. We examined the role of receptor interacting protein (RIP) 3, a mediator of necrotic cell death, in atherosclerosis and found that RIP3−/−;Ldlr−/− mice were no different from RIP3+/+;Ldlr−/− mice in early atherosclerosis but had significant reduction in advanced atherosclerotic lesions. Similar results were observed in Apoe−/− background mice. Bone marrow transplantation reveal...

Work Scope for Developing Standards for Emergency Preparedness and Response: Fiscal Year 2004 Final Report

Energy Technology Data Exchange (ETDEWEB)

Stenner, Robert D.

2005-09-28

Summarizes the fiscal year 2004 work completed on PNNL's Department of Homeland Security Emergency Preparedness and Response Standards Development Project. Also, the report includes key draft standards, in various stages of development and publication, that were associated with various tasks of the fiscal year 2004 scope of the project.

75 FR 45632 - Animal Drug User Fee Rates and Payment Procedures for Fiscal Year 2011

Science.gov (United States)

2010-08-03

...), beginning with the letters AD, from the upper right-hand corner of your completed Animal Drug User Fee Cover...] Animal Drug User Fee Rates and Payment Procedures for Fiscal Year 2011 AGENCY: Food and Drug... payment procedures for fiscal year (FY) 2011 animal drug user fees. The Federal Food, Drug, and Cosmetic...

Influence of slope and gradation on rip rap stability and degradation mechanisms

International Nuclear Information System (INIS)

Lefebvre, G.; Rohan, K.; Belfahdel, M. B.

1997-01-01

A major investigation was undertaken at the La Grande hydroelectric complex with some 220 dikes and dams to study rip rap stability and repair. Degradation mechanisms were also studied under laboratory conditions to verify the main field study conclusions and to test different repair techniques. The result of both laboratory and field observation was that rip rap gradation has only marginal effect on slope stability and degradation mechanisms. On the other hand, the inclusion of even a small fraction of fine blocks (as little as 10 per cent) into the rip rap was shown to be very detrimental to the stability of steep rip rap but only marginally effective on flat slopes. 15 refs., 8 figs

XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation

DEFF Research Database (Denmark)

Yabal, Monica; Müller, Nicole; Adler, Heiko

2014-01-01

of XIAP or deletion of its RING domain lead to excessive cell death and IL-1β secretion from dendritic cells triggered by diverse Toll-like receptor stimuli. Aberrant IL-1β secretion is TNF dependent and requires RIP3 but is independent of cIAP1/cIAP2. The observed cell death also requires TNF and RIP3...... but proceeds independently of caspase-1/caspase-11 or caspase-8 function. Loss of XIAP results in aberrantly elevated ubiquitylation of RIP1 outside of TNFR complex I. Virally infected Xiap(-/-) mice present with symptoms reminiscent of XLP-2. Our data show that XIAP controls RIP3-dependent cell death and IL-1...

Financial Audit: IRS's Fiscal Years 2001 and 2000 Financial Statements

National Research Council Canada - National Science Library

2002-01-01

...) as of and for the fiscal years ending September 30, 2001, and 2000. Our audits were required by the Chief Financial Officers Act of 1990, as expanded by the Government Management Reform Act of 1994...

75 FR 33324 - Notice of Availability: Notice of Funding Availability (NOFA) for Fiscal Year (FY) 2009...

Science.gov (United States)

2010-06-11

... requirements established by HUD's Fiscal Year 2009 Notice of Funding Availability (NOFA) Policy Requirements... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5419-N-01] Notice of Availability: Notice of Funding Availability (NOFA) for Fiscal Year (FY) 2009; Brownfields Economic Development...

Phantom cosmology without Big Rip singularity

Energy Technology Data Exchange (ETDEWEB)

Astashenok, Artyom V. [Baltic Federal University of I. Kant, Department of Theoretical Physics, 236041, 14, Nevsky st., Kaliningrad (Russian Federation); Nojiri, Shin' ichi, E-mail: nojiri@phys.nagoya-u.ac.jp [Department of Physics, Nagoya University, Nagoya 464-8602 (Japan); Kobayashi-Maskawa Institute for the Origin of Particles and the Universe, Nagoya University, Nagoya 464-8602 (Japan); Odintsov, Sergei D. [Department of Physics, Nagoya University, Nagoya 464-8602 (Japan); Institucio Catalana de Recerca i Estudis Avancats - ICREA and Institut de Ciencies de l' Espai (IEEC-CSIC), Campus UAB, Facultat de Ciencies, Torre C5-Par-2a pl, E-08193 Bellaterra (Barcelona) (Spain); Tomsk State Pedagogical University, Tomsk (Russian Federation); Yurov, Artyom V. [Baltic Federal University of I. Kant, Department of Theoretical Physics, 236041, 14, Nevsky st., Kaliningrad (Russian Federation)

2012-03-23

We construct phantom energy models with the equation of state parameter w which is less than -1, w<-1, but finite-time future singularity does not occur. Such models can be divided into two classes: (i) energy density increases with time ('phantom energy' without 'Big Rip' singularity) and (ii) energy density tends to constant value with time ('cosmological constant' with asymptotically de Sitter evolution). The disintegration of bound structure is confirmed in Little Rip cosmology. Surprisingly, we find that such disintegration (on example of Sun-Earth system) may occur even in asymptotically de Sitter phantom universe consistent with observational data. We also demonstrate that non-singular phantom models admit wormhole solutions as well as possibility of Big Trip via wormholes.

NASA's Morphing Project Research Summaries in Fiscal Year 2002

Science.gov (United States)

McGowan, Anna-Maria R.; Waszak, Martin R.

2005-01-01

The Morphing Project at the National Aeronautics and Space Agency s (NASA) Langley Research Center (LaRC) is part of the Breakthrough Vehicle Technologies Project, Vehicle Systems Program that conducts fundamental research on advanced technologies for future flight vehicles. The objectives of the Morphing Project are to develop and assess the advanced technologies and integrated component concepts to enable efficient, multi-point adaptability of flight vehicles; primarily through the application of adaptive structures and adaptive flow control to substantially alter vehicle performance characteristics. This document is a compilation of research summaries and other information on the project for fiscal year 2002. The focus is to provide a brief overview of the project content, technical results and lessons learned. At the time of publication, the Vehicle Systems Program (which includes the Morphing Project) is undergoing a program re-planning and reorganization. Accordingly, the programmatic descriptions of this document pertain only to the program as of fiscal year 2002.

Drug dealers' rational choices on which customers to rip-off.

Science.gov (United States)

Jacques, Scott; Allen, Andrea; Wright, Richard

2014-03-01

Drug dealers are infamous for overcharging customers and handing over less than owed. One reason rip-offs frequently occur is blackmarket participants have limited access to formal means of dispute resolution and, as such, are attractive prey. Yet drug dealers do not cheat every customer. Though this is implicitly understood in the literature, sparse theoretical attention has been given to which customers are ripped-off and why. To address that lacuna, this paper uses the rationality perspective to analyze qualitative data obtained in interviews with 25 unincarcerated drug sellers operating in disadvantaged neighborhoods of St. Louis, Missouri. We find that dealers typically rip-off six types of customers: persons who are strangers, first-time or irregular customers; do not have sufficient money on hand to make a purchase; are uninformed about going market rates; are deemed unlikely to retaliate; are offensive; or are addicted to drugs. Dealers target these groups due to perceiving them as unlikely to be repeat business; not worth the hassle of doing business with; unlikely to realize they are being ripped-off; in the wrong and thus deserving of payback; and, unwilling to retaliate or take their money elsewhere. Our findings are discussed in relation to their practical implications, including the importance of giving blackmarket participants greater access to law, and how customers may prevent being ripped-off. Copyright © 2013 Elsevier B.V. All rights reserved.

Rip current evidence by hydrodynamic simulations, bathymetric surveys and UAV observation

Directory of Open Access Journals (Sweden)

G. Benassai

2017-09-01

Full Text Available The prediction of the formation, spacing and location of rip currents is a scientific challenge that can be achieved by means of different complementary methods. In this paper the analysis of numerical and experimental data, including RPAS (remotely piloted aircraft systems observations, allowed us to detect the presence of rip currents and rip channels at the mouth of Sele River, in the Gulf of Salerno, southern Italy. The dataset used to analyze these phenomena consisted of two different bathymetric surveys, a detailed sediment analysis and a set of high-resolution wave numerical simulations, completed with Google EarthTM images and RPAS observations. The grain size trend analysis and the numerical simulations allowed us to identify the rip current occurrence, forced by topographically constrained channels incised on the seabed, which were compared with observations.

Fiscal Year 2014 United States Army Annual Financial Report: Maintaining Readiness Through Fiscal Responsibility

Science.gov (United States)

2014-01-01

citizens at home, to combating insurgents abroad. Providing Advanced Technologies The Army’s Science and Technology (S&T) investments support Army...Construction 29,892,790 33,309,504 (Less: Earned Revenue) $ (14,868,782) $ (14,584,858) Net Cost before Losses/(Gains) from Actuarial Assumption Changes for...Benefits consist of various employee actuarial liabilities not due and payable during the current fiscal year. These liabilities consist primarily

Financial Management: Improper Payments Reported in Fiscal Year 2000 Financial Statements

National Research Council Canada - National Science Library

2001-01-01

...). Specifically, it provides information on the amount of improper payments' that federal agencies reported in their fiscal year 2000 financial statements and identifies some current improper payment...

Budget of the U.S. Government, Fiscal Year 2017

Science.gov (United States)

Office of Management and Budget, Executive Office of the President, 2016

2016-01-01

"Budget of the United States Government, Fiscal Year 2017" contains the Budget Message of the President, information on the President's priorities, and summary tables. President Obama's 2017 Budget makes critical investments while adhering to the bipartisan budget agreement he signed into the previous fall, and it lifts sequestration in…

Mizunami Underground Research Project. Annual report in the 2003 fiscal year

International Nuclear Information System (INIS)

Nakama, Shigeo; Takeuchi, Shinji; Amano, Kenji

2004-12-01

The current geoscientific research of the Mizunami Underground Research Laboratory (MIU) Project have been carried out since the 1996 fiscal year at the Shobasama Site in Akeyo-cho, Mizunami City, Gifu Prefecture. The main goals of MIU Project are to establish appropriate methodologies for reliably investigation and assessing a deep subsurface, and to develop a range of engineering techniques for deep underground application in granite. The surface-based investigations at city-owned land (MIU Construction Site) have started since the 2001 fiscal year. In 2003 fiscal year, deep borehole investigations were continued in the MIU Construction Site. To understand the state of the deep geological environment before shaft sinking based on these investigations and research, a geological environmental model in/around the MIU Construction Site was constructed. In addition to there groundwater monitoring was carried out using shallow boreholes. As a research on the engineering technology, the review of the design and construction plan of the shafts and galleries and the outbreak event measures and security measures were provided. In Shobasama site, the analysis of an uncertain factor was executed based on the results of the underground water flow analysis. The hydraulic pressure monitoring and surface hydraulic observation were continued. (author)

Congressional Budget Action for Fiscal Year 2012 and Its Impact on Education Funding. Issue Brief

Science.gov (United States)

Delisle, Jason

2011-01-01

The fiscal year 2012 budget process has been anything but typical or predictable. While fiscal year 2012 starts in just a few weeks on October 1, 2011, the annual appropriations process is far from complete, and funding for federal education programs has not yet been finalized. Nevertheless, congressional action in the months that have led up to…

RCRA and operational monitoring 1994 fiscal year work plan, WBS 1.5.3

Energy Technology Data Exchange (ETDEWEB)

1993-12-01

RCRA & Operational Monitoring (ROM) Program Office manages the direct funded Resource Conservation Recovery Act (RCRA) and Operational Monitoring under Work Breakdown Structure (WBS) 1.5.3. The ROM Program Office is a Branch of liquid Waste Disposal, a part of Restoration and Remediation of Westinghouse Hanford Company (WHC). The Fiscal Year Work Plan (FYWP) takes it direction from the Multi-Year Program Plan (MYPP). The FYWP provides the near term, enhanced details for the Program Office to use as baseline Cost, Scope and Schedule. Changs Control administered during the fiscal year is against the baseline provided by the FYWP.

RCRA and operational monitoring 1994 fiscal year work plan, WBS 1.5.3

International Nuclear Information System (INIS)

1993-12-01

RCRA ampersand Operational Monitoring (ROM) Program Office manages the direct funded Resource Conservation Recovery Act (RCRA) and Operational Monitoring under Work Breakdown Structure (WBS) 1.5.3. The ROM Program Office is a Branch of liquid Waste Disposal, a part of Restoration and Remediation of Westinghouse Hanford Company (WHC). The Fiscal Year Work Plan (FYWP) takes it direction from the Multi-Year Program Plan (MYPP). The FYWP provides the near term, enhanced details for the Program Office to use as baseline Cost, Scope and Schedule. Changs Control administered during the fiscal year is against the baseline provided by the FYWP

Report: Fiscal Year 2010 Federal Information Security Management Act Report

Science.gov (United States)

Report #11-P-0017, November 16, 2010. Attached is the Office of Inspector General’s (OIG’s) Fiscal Year 2010 Federal Information Security Management Act (FISMA) Reporting Template, as prescribed by the Office of Management and Budget (OMB).

75 FR 20578 - Availability of the Fiscal Year 2008 Defense Threat Reduction Agency Services Contracts Inventory

Science.gov (United States)

2010-04-20

... DEPARTMENT OF DEFENSE Office of the Secretary Availability of the Fiscal Year 2008 Defense Threat... amended by the National Defense Authorization Act for Fiscal Year 2008 (NDAA 08) section 807, the Director of DTRA and the Office of the Director, Defense Procurement and Acquisition Policy, Office of...

76 FR 66051 - Availability of the Fiscal Year 2010 United States Special Operations Command (USSOCOM) Inventory...

Science.gov (United States)

2011-10-25

... DEPARTMENT OF DEFENSE Office of the Secretary Availability of the Fiscal Year 2010 United States... Authorization Act for Fiscal Year 2008 (NDAA 08) Section 807, the Director of Procurement USSOCOM and the Office of the Director, Defense Procurement and Acquisition Policy, Office of Strategic Sourcing (DPAP/SS...

Fusion Safety Program annual report, fiscal year 1983

International Nuclear Information System (INIS)

Crocker, J.G.; Holland, D.F.

1984-07-01

The Fusion Safety Program major activities for Fiscal Year 1983 are summarized in this report. The program was initiated in FY 1979, with the Idaho National Engineering Laboratory (INEL) designated lead laboratory, and EG and G Idaho, inc., named as prime contractor to implement this role. The report contains four sections: EG and G Idaho, Inc., activities at the INEL includes progress reports and portions of papers on the tritium implantation experiment, tritium control systems, tritium release from solid breeding blankets, plasma disruptions, risk assessment, transient code development, data base development, and a discussion of participation in the blanket comparison and selection study. The section outside contracts includes progress reports and portions of papers on lithium-lead reactions by Hanford Engineering Development Laboratory (HEDL) and the University of Wisconsin, magnet safety by the Francis Bitter Magnet Laboratory of the Massachusetts Institute of Technology (MIT) and Argonne National Laboratory (ANL), risk assessment by the University of California at Los Angeles (UCLA) and MIT, tritium retention by the University of Virginia, and effects of plasma disruptions by MIT. A list of publications and planned fiscal year 1984 activities are also included

Alternative mechanism of avoiding the big rip or little rip for a scalar phantom field

International Nuclear Information System (INIS)

Xi Ping; Zhai Xianghua; Li Xinzhou

2012-01-01

Depending on the choice of its potential, the scalar phantom field φ (the equation of state parameter w 2 correction. The singularity is avoidable under all these potentials. Hence, we conclude that the avoidance of big or little rip is hardly dependent on special potential.

Transmutation Fuel Fabrication-Fiscal Year 2016

Energy Technology Data Exchange (ETDEWEB)

Fielding, Randall Sidney [Idaho National Lab. (INL), Idaho Falls, ID (United States); Grover, Blair Kenneth [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2016-12-01

ABSTRACT Nearly all of the metallic fuel that has been irradiated and characterized by the Advanced Fuel Campaign, and its earlier predecessors, has been arc cast. Arc casting is a very flexible method of casting lab scale quantities of materials. Although the method offers flexibility, it is an operator dependent process. Small changes in parameter space or alloy composition may affect how the material is cast. This report provides a historical insight in how the casting process has been modified over the history of the advanced fuels campaign as well as the physical parameters of the fuels cast in fiscal year 2016.

Atomic energy policy in fiscal year 1985

International Nuclear Information System (INIS)

Sakurada, Michio

1985-01-01

The international demand and supply of petroleum advance in relaxed condition at present, but tend to get stringent in long term. Nuclear power is the most promising substitute energy for petroleum, and in Japan, 28 nuclear power plants with 20.56 million kW output are in operation, generating 20.4% of the total generated power in 1983. According to the perspective of long term power supply, the installed capacity of nuclear power plants will reach 62 million kW and 27% of the total installed capacity by 2000. It is important to positively deal with the industrialization of nuclear fuel cycle, the upgrading of nuclear power generation, the development of the reactors of new types and so on, preparing for the age that nuclear power generation will become the center of power supply. The atomic energy policy of the Ministry of International Trade and Industry in fiscal year 1985 is reflected to the budget, financial investment and funding and other measures based on the above viewpoint. The outline of the budget and financial investment and funding for fiscal year 1985 is explained. The points are the promotion of industrialization of nuclear fuel cycle, the promotion of nuclear power generation and the promotion of understanding and cooperation of nation on the location of electric power sources. (Kako, I.)

Budget of the U.S. Government, Fiscal Year 2014

Science.gov (United States)

Office of Management and Budget, Executive Office of the President, 2013

2013-01-01

"Budget of the United States Government, Fiscal Year 2014" contains the Budget Message of the President, information on the President's priorities, budget overviews organized by agency, and summary tables. President Obama believes the country must invest in the true engine of America's economic growth--a rising and thriving middle class.…

On tridimensional rip current modeling

Science.gov (United States)

Marchesiello, Patrick; Benshila, Rachid; Almar, Rafael; Uchiyama, Yusuke; McWilliams, James C.; Shchepetkin, Alexander

2015-12-01

Do lateral shear instabilities of nearshore circulation account for a substantial part of Very Low-Frequency (VLF) variability? If yes, it would promote stirring and mixing of coastal waters and surf-shelf exchanges. Another question is whether tridimensional transient processes are important for instability generation. An innovative modeling system with tridimensional wave-current interactions was designed to investigate transient nearshore currents and interactions between nearshore and innershelf circulations. We present here some validation of rip current modeling for the Aquitanian coast of France, using in-situ and remote video sensing. We then proceed to show the benefits of 3D versus 2D (depth-mean flow) modeling of rip currents and their low-frequency variability. It appears that a large part of VLF motions is due to intrinsic variability of the tridimensional flow. 3D models may thus provide a valuable, only marginally more expensive alternative to conventional 2D approaches that miss the vertical flow structure and its nonlinear interaction with the depth-averaged flow.

National Low-Level Waste Management Program final summary report of key activities and accomplishments for fiscal year 1996

International Nuclear Information System (INIS)

Garcia, R.S.

1996-12-01

To assist the Department of Energy (DOE) in fulfilling its responsibilities under the Low-Level Radioactive Waste Policy Amendments Act of 1985, the National Low-Level Waste Management Program (NLLWMP) outlines the key activities tat the NLLWMP will accomplish in the following fiscal year. Additional activities are added during the fiscal year as necessary to accomplish programmatic goals. This report summarizes the activities and accomplishments of the NLLWMP during Fiscal Year 1996

National Low-Level Waste Management Program final summary report of key activities and accomplishments for fiscal year 1995

International Nuclear Information System (INIS)

Forman, S.

1995-12-01

To assist the Department of Energy (DOE) in fulfilling its responsibilities under the Low-Level Radioactive Waste Policy Amendments Act of 1985, the National Low-Level Waste Management Program (NLLWMP) outlines the key activities that the NLLWMP will accomplish in the following fiscal year. Additional activities are added during the fiscal year as necessary to accomplish programmatic goals. This report summarizes the activities and accomplishments of the NLLWMP during fiscal year 1995

Atomic Safety and Licensing Board Panel Biennial Report, Fiscal Years 1993--1994. Volume 6

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-08-01

In Fiscal Year 1993, the Atomic Safety and Licensing Board Panel (``the Panel``) handled 30 proceedings. In Fiscal Year 1994, the Panel handled 36 proceedings. The cases addressed issues in the construction, operation, and maintenance of commercial nuclear power reactors and other activities requiring a license form the Nuclear Regulatory Commission. This report sets out the Panel`s caseload during the year and summarizes, highlight, and analyzes how the wide- ranging issues raised in those proceedings were addressed by the Panel`s judges and licensing boards.

Atomic Safety and Licensing Board Panel Biennial Report, Fiscal Years 1993--1994. Volume 6

International Nuclear Information System (INIS)

1995-08-01

In Fiscal Year 1993, the Atomic Safety and Licensing Board Panel (''the Panel'') handled 30 proceedings. In Fiscal Year 1994, the Panel handled 36 proceedings. The cases addressed issues in the construction, operation, and maintenance of commercial nuclear power reactors and other activities requiring a license form the Nuclear Regulatory Commission. This report sets out the Panel's caseload during the year and summarizes, highlight, and analyzes how the wide- ranging issues raised in those proceedings were addressed by the Panel's judges and licensing boards

Outline of results of safety research (in nuclear fuel cycle field in fiscal year 1996)

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-12-01

The safety research in Power Reactor and Nuclear Fuel Development Corporation in fiscal year 1996 has been carried out based on the basic plan of safety research (from fiscal year 1996 to 2000) which was decided in March, 1996. In this report, on nuclear fuel cycle field, namely all the subjects in the fields of nuclear fuel facilities, environmental radioactivity and waste disposal, and the subjects related to nuclear fuel facilities among the fields of aseismatic and probabilistic safety assessments, the results of research in fiscal year 1996, the first year of the 5-year project, are summarized together with the outline of the basic plan of safety research. The basic policy, objective and system for promotion of the safety research are described. The objectives of the safety research are the advancement of safety technology, the safety of facilities, stable operation techniques, the safety design and the evaluation techniques of next generation facilities, and the support of transferring nuclear fuel cycle to private businesses. The objects of the research are uranium enrichment, fuel fabrication and reprocessing, and waste treatment and storage. 52 investigation papers of the results of the safety research in nuclear fuel cycle field in fiscal year 1996 are collected in this report. (K.I.)

76 FR 4322 - Availability of the Fiscal Year 2009 Missile Defense Agency Services Contracts Inventory Pursuant...

Science.gov (United States)

2011-01-25

... DEPARTMENT OF DEFENSE Office of the Secretary Availability of the Fiscal Year 2009 Missile Defense... Act AGENCY: Missile Defense Agency (MDA), DoD. ACTION: Notice of availability. SUMMARY: In accordance... for Fiscal Year 2008 (NDAA 08) Section 807, the Director of the Missile Defense Agency and the Office...

Fiscal Year 2014 Revegetation Assessment

Energy Technology Data Exchange (ETDEWEB)

Nordstrom, Jenifer [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2015-03-01

This report summarizes the Fiscal Year 2014 Revegetation Assessment by Battelle Energy Alliance, LLC. This assessment was conducted to document revegetation efforts at Idaho National Laboratory to ensure that disturbed vegetation and soil at various locations are being restored. This report provides the following information for each site being monitored by the Idaho National Laboratory Environmental Support and Services: • Summary of each site • Assessment of vegetation status and site stabilization at each location • Actions and Resolutions for each site. Five disturbed sites were evaluated for this assessment. Four sites are recommended to be removed from the annual assessment, and one is recommended for continued evaluation. New sites are also identified for future monitoring as part of the annual assessment.

Ohio Department of Transportation Financial & Statistical Report : Fiscal Year 2007

Science.gov (United States)

2007-01-01

On behalf of the dedicated men and women of the Ohio Department of Transportation, I share with : you this Financial and Statistical Report for State Fiscal Year 2007, documenting the state and : federal dollars invested by ODOT into preserving, main...

Results on safety research for five years (from fiscal year 1996 to 2000). A field of power reactors

International Nuclear Information System (INIS)

2001-10-01

This safety research carried out by the Japan Nuclear Cycle Development Institute (JNC) for five years ranged from 1996 to 2000 fiscal year, was performed according to the safety research basic plan (from 1996 to 2000 fiscal year) established on March, 1996 (revised again on May, 2000). This report was arranged on a field on power reactors (all subjects on fields of advanced conversion reactor and a subject on power reactor in a field of seismic resistant and probability theoretical safety evaluation) by combining its research results for five years ranged from 1996 to 2000 fiscal year with general outlines on the safety research basic plan. Here were shown outlines on the safety research basic plan, aims and subjects on safety research at a field of power reactors, a list of survey sheets on safety research result, and survey sheets on safety research results. The survey sheets containing research field, title, organization, researcher name, researching period, names of cooperative organization, using facilities, research outline, research results, established contents, application, and research trends, are ranged to 5 items on advanced conversion reactor, 29 items on high breeder reactor, 1 item on seismic resistance, and 5 items on probability theoretical safety evaluation. (G.K.)

Idaho National Laboratory Emergency Readiness Assurance Plan — Fiscal Year 2016

International Nuclear Information System (INIS)

None, None

2016-01-01

Battelle Energy Alliance, LLC, the prime contractor for Idaho National Laboratory (INL), provides this Emergency Readiness Assurance Plan (ERAP) for Fiscal Year 2016 in accordance with DOE O 151.1C, “Comprehensive Emergency Management System.” The ERAP documents the readiness of the INL Emergency Management Program using emergency response planning and preparedness activities as the basis. It describes emergency response planning and preparedness activities, and where applicable, summarizes and/or provides supporting information in tabular form for easy access to data. The ERAP also provides budget, personnel, and planning forecasts for Fiscal Year 2017. Specifically, the ERAP assures the Department of Energy Idaho Operations Office that stated emergency capabilities at INL are sufficient to implement PLN 114, “INL Emergency Plan/RCRA Contingency Plan.”

Idaho National Laboratory Emergency Readiness Assurance Plan — Fiscal Year 2014

Energy Technology Data Exchange (ETDEWEB)

Bush, Shane [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2014-09-01

Battelle Energy Alliance, LLC, the prime contractor for Idaho National Laboratory (INL), provides this Emergency Readiness Assurance Plan (ERAP) for Fiscal Year 2014 in accordance with DOE O 151.1C, “Comprehensive Emergency Management System.” The ERAP documents the readiness of the INL Emergency Management Program using emergency response planning and preparedness activities as the basis. It describes emergency response planning and preparedness activities, and where applicable, summarizes and/or provides supporting information in tabular form for easy access to data. The ERAP also provides budget, personnel, and planning forecasts for Fiscal Year 2015. Specifically, the ERAP assures the Department of Energy Idaho Operations Office that stated emergency capabilities at INL are sufficient to implement PLN-114, “INL Emergency Plan/RCRA Contingency Plan.”

Estimation of the fiscal year 1985 expenditures in nuclear energy relation

International Nuclear Information System (INIS)

1985-01-01

In Japan, the electric power by nuclear energy accounts for about 20 % of the total power at present. Then, radiation is utilized extensively in such fields as industries, agriculture and medicine. The expenditures (budgets) estimated for the fiscal year 1985 are about 343.8 billion yen plus contract authorization limitation about 146.7 billion yen. In connection with the expenditures estimation (of which a breakdown is given in tables), the research and development plans for nuclear energy relation for fiscal year 1985 are presented: strengthening in nuclear energy safety, promotion of nuclear power generation, establishment of the nuclear fuel cycle, development of advanced power reactors, research on nuclear fusion, promotion of radiation utilizations, strengthening in the research and development infrastructure, promotion of international cooperation, etc. (Mori, K.)

Idaho National Laboratory Emergency Readiness Assurance Plan — Fiscal Year 2016

Energy Technology Data Exchange (ETDEWEB)

None, None

2016-09-13

Battelle Energy Alliance, LLC, the prime contractor for Idaho National Laboratory (INL), provides this Emergency Readiness Assurance Plan (ERAP) for Fiscal Year 2016 in accordance with DOE O 151.1C, “Comprehensive Emergency Management System.” The ERAP documents the readiness of the INL Emergency Management Program using emergency response planning and preparedness activities as the basis. It describes emergency response planning and preparedness activities, and where applicable, summarizes and/or provides supporting information in tabular form for easy access to data. The ERAP also provides budget, personnel, and planning forecasts for Fiscal Year 2017. Specifically, the ERAP assures the Department of Energy Idaho Operations Office that stated emergency capabilities at INL are sufficient to implement PLN 114, “INL Emergency Plan/RCRA Contingency Plan.”

Biochemical, structural and molecular dynamics analyses of the potential virulence factor RipA from Yersinia pestis.

Directory of Open Access Journals (Sweden)

Rodrigo Torres

Full Text Available Human diseases are attributed in part to the ability of pathogens to evade the eukaryotic immune systems. A subset of these pathogens has developed mechanisms to survive in human macrophages. Yersinia pestis, the causative agent of the bubonic plague, is a predominately extracellular pathogen with the ability to survive and replicate intracellularly. A previous study has shown that a novel rip (required for intracellular proliferation operon (ripA, ripB and ripC is essential for replication and survival of Y. pestis in postactivated macrophages, by playing a role in lowering macrophage-produced nitric oxide (NO levels. A bioinformatics analysis indicates that the rip operon is conserved among a distally related subset of macrophage-residing pathogens, including Burkholderia and Salmonella species, and suggests that this previously uncharacterized pathway is also required for intracellular survival of these pathogens. The focus of this study is ripA, which encodes for a protein highly homologous to 4-hydroxybutyrate-CoA transferase; however, biochemical analysis suggests that RipA functions as a butyryl-CoA transferase. The 1.9 Å X-ray crystal structure reveals that RipA belongs to the class of Family I CoA transferases and exhibits a unique tetrameric state. Molecular dynamics simulations are consistent with RipA tetramer formation and suggest a possible gating mechanism for CoA binding mediated by Val227. Together, our structural characterization and molecular dynamic simulations offer insights into acyl-CoA specificity within the active site binding pocket, and support biochemical results that RipA is a butyryl-CoA transferase. We hypothesize that the end product of the rip operon is butyrate, a known anti-inflammatory, which has been shown to lower NO levels in macrophages. Thus, the results of this molecular study of Y. pestis RipA provide a structural platform for rational inhibitor design, which may lead to a greater understanding of the

Budget of the U.S. Government, Fiscal Year 2016

Science.gov (United States)

Office of Management and Budget, Executive Office of the President, 2015

2015-01-01

"Budget of the United States Government, Fiscal Year 2016" contains the Budget Message of the President, information on the President's priorities, and summary tables. The ideas offered by President Obama in this 2016 Budget are designed to bring middle-class economics into the 21st Century. They are intended to help working families…

Fundamental plan of atomic energy development and utilization in fiscal year 1986

International Nuclear Information System (INIS)

1986-01-01

The Prime Minister made the fundamental plan of atomic energy development and utilization in fiscal year 1986 based on the decision of Nuclear Safety Commission on March 13, 1986, and the decision of Atomic Energy Commission on March 18, 1986, in conformity with the law concerning Japan Atomic Energy Research Institute, and asked the opinion of Nuclear Safety Commission. After the deliberation, the Nuclear Safety Commission made the report same as the original draft on March 27, 1986. The outline of the measures taken in fiscal year 1986 is as follows. The strengthening of the measures for ensuring safety, the promotion of nuclear power generation, the establishment of nuclear fuel cycle, the development of the reactors of new types, the research on nuclear fusion, the research and development of nuclear-powered ships, the promotion of the utilization of radiation, the strengthening of the base for atomic energy development and utilization, the promotion of international cooperation, and the strengthening of safeguard measures and the countermeasures for the protection of nuclear substances. The total budget related to atomic energy for fiscal year 1986 is 357.3 billion yen. (Kako, I.)

77 FR 45629 - Animal Generic Drug User Fee Rates and Payment Procedures for Fiscal Year 2013

Science.gov (United States)

2012-08-01

..., beginning with the letters ``AG'', from the upper right-hand corner of your completed Animal Generic Drug...] Animal Generic Drug User Fee Rates and Payment Procedures for Fiscal Year 2013 AGENCY: Food and Drug... payment procedures for fiscal year (FY) 2013 generic new animal drug user fees. The Federal Food, Drug...

75 FR 75851 - Fiscal Year 2011 Refugee Admissions Numbers and Authorizations of In-Country Refugee Status...

Science.gov (United States)

2010-12-07

... October 8, 2010 Fiscal Year 2011 Refugee Admissions Numbers and Authorizations of In-Country Refugee... Determination Pursuant to Section 2(b)(2) of the Migration and Refugee Assistance Act, as Amended Memorandum for... refugees to the United States during Fiscal Year (FY) 2011 is justified by humanitarian concerns or is...

Science to Support DOE Site Cleanup: The Pacific Northwest National Laboratory Environmental Management Science Program Awards-Fiscal Year 1999 Mid-Year Progress Report

International Nuclear Information System (INIS)

Peurrung, L.M.

1999-05-01

Pacific Northwest National Laboratory was awarded ten Environmental Management Science Program (EMSP) research grants in fiscal year 1996, six in fiscal year 1997, and eight in fiscal year 1998. This section summarizes how each grant addresses significant U.S. Department of Energy (DOE) cleanup issues, including those at the Hanford Site. The technical progress made to date in each of these research projects is addressed in more detail in the individual progress reports contained in this document. This research is focused primarily in five areas: Tank Waste Remediation, Decontamination and Decommissioning, Spent Nuclear Fuel and Nuclear Materials, Soil and Groundwater Clean Up, and Health Effects

Science to Support DOE Site Cleanup: The Pacific Northwest National Laboratory Environmental Management Science Program Awards-Fiscal Year 1999 Mid-Year Progress Report

Energy Technology Data Exchange (ETDEWEB)

Peurrung, L.M.

1999-06-30

Pacific Northwest National Laboratory was awarded ten Environmental Management Science Program (EMSP) research grants in fiscal year 1996, six in fiscal year 1997, and eight in fiscal year 1998. This section summarizes how each grant addresses significant U.S. Department of Energy (DOE) cleanup issues, including those at the Hanford Site. The technical progress made to date in each of these research projects is addressed in more detail in the individual progress reports contained in this document. This research is focused primarily in five areas: Tank Waste Remediation, Decontamination and Decommissioning, Spent Nuclear Fuel and Nuclear Materials, Soil and Groundwater Clean Up, and Health Effects.

RIP-ET: A riparian evapotranspiration package for MODFLOW-2005

Science.gov (United States)

Maddock, Thomas; Baird, Kathryn J.; Hanson, R.T.; Schmid, Wolfgang; Ajami, Hoori

2012-01-01

A new evapotranspiration package for the U.S. Geological Survey's groundwater-flow model, MODFLOW, is documented. The Riparian Evapotranspiration Package (RIP-ET) provides flexibility in simulating riparian and wetland transpiration not provided by the Evapotranspiration (EVT) or Segmented Function Evapotranspiration (ETS1) Packages for MODFLOW 2005. This report describes how the RIP-ET package was conceptualized and provides input instructions, listings and explanations of the source code, and an example. Traditional approaches to modeling evapotranspiration (ET) processes assume a piecewise linear relationship between ET flux and hydraulic head. The RIP-ET replaces this traditional relationship with a segmented, nonlinear dimensionless curve that reflects the eco-physiology of riparian and wetland ecosystems. Evapotranspiration losses from these ecosystems are dependent not only on hydraulic head, but on the plant types present. User-defined plant functional groups (PFGs) are used to elucidate the interaction between plant transpiration and groundwater conditions. Five generalized plant functional groups based on transpiration rates, plant rooting depth, and water tolerance ranges are presented: obligate wetland, shallow-rooted riparian, deep-rooted riparian, transitional riparian and bare ground/open water. Plant functional groups can be further divided into subgroups (PFSGs) based on plant size, density or other characteristics. The RIP-ET allows for partial habitat coverage and mixtures of plant functional subgroups to be present in a single model cell. RIP-ET also distinguishes between plant transpiration and bare-ground evaporation. Habitat areas are designated by polygons; each polygon can contain a mixture of PFSGs and bare ground, and is assigned a surface elevation. This process requires a determination of fractional coverage for each of the plant functional subgroups present in a polygon to account for the mixture of coverage types and resulting

Public Company Bankruptcy Cases Opened and Monitored for Fiscal Year 2009

Data.gov (United States)

Securities and Exchange Commission — This file contains all of the bankruptcy cases for public companies opened and monitored in the fiscal year 2009. The data includes the District Court, the state,...

Potential for yield improvement in combined rip-first and crosscut-first rough mill processing

Science.gov (United States)

Ed Thomas; Urs Buehlmann

2016-01-01

Traditionally, lumber cutting systems in rough mills have either first ripped lumber into wide strips and then crosscut the resulting strips into component lengths (rip-first), or first crosscut the lumber into component lengths, then ripped the segments to the required widths (crosscut-first). Each method has its advantages and disadvantages. Crosscut-first typically...

Relevance of Radiocaesium Interception Potential (RIP) on a worldwide scale to assess soil vulnerability to 137Cs contamination

International Nuclear Information System (INIS)

Vandebroek, Louis; Van Hees, May; Delvaux, Bruno; Spaargaren, Otto; Thiry, Yves

2012-01-01

The extent of radiocaesium retention in soil is important to quantify the risk of further foodchain contamination. The Radiocaesium Interception Potential (RIP –, Nature 335, 247–249) is an intrinsic soil parameter which can be used to categorize soils or minerals in terms of their capacity to selectively adsorb radiocaesium. In this study, we measured RIP for a large soil collection (88 soil samples) representative of major FAO soil reference groups on a worldwide scale and tested the possibility to predict the RIP on the basis of other easily accessible or measurable soil data. We also compared RIP values with those obtained from separate chemical extraction experiments. The range of measured RIP values (1.8–13300 mmol kg −1 ) was shown to include nearly all possible cases of agricultural soil contamination. Only Podzols, Andosols and Ferralsols were clearly characterized by a very low RIP ( −1 ). On a worldwide scale, RIP was in fact slightly related to soil reference type or other simple major physicochemical parameters such as clay percentage or organic matter. Conversely our results indicated a link between the RIP and radiocaesium extractability across very different soils. We showed that, with the proposed scale of RIP values, a simple acid extraction method can provide an operational result highly predictive of potential RIP despite very contrasting soil properties. The RIP could be estimated from the empirical equation: RIP = (−31.701 ∗ log(AER) + 58.886) 2 where AER is the fraction of acid-extractable radiocaesium. - Highlights: ► The Radiocaesium Interception Potential (RIP) is an intrinsic soil parameter. ► We measured RIP of 88 different soils representative of major FAO reference groups. ► The range of RIP (1.8–13 343 μmol g −1 ) extended over four orders of magnitude. ► Nearly all possible cases of agricultural soils contamination were represented. ► A simple acid extraction method could be used to predict potential RIP.

75 FR 66385 - Notice of Availability: Notice of Funding Availability (NOFA) for Fiscal Year 2010; Special Needs...

Science.gov (United States)

2010-10-28

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5415-N-31] Notice of Availability: Notice of Funding Availability (NOFA) for Fiscal Year 2010; Special Needs Assistance Programs (SNAPS... information, and other requirements for the Fiscal Year (FY) 2010 Special Needs Assistance Programs Technical...

Solid waste programs Fiscal Year 1995 multi-year program plan/fiscal year work plan WBS 1.2.1

International Nuclear Information System (INIS)

McCarthy, M.M.

1994-09-01

The Hanford Mission Plan, Volume 1, Site Guidance identifies the need for the Solid Waste Program to treat, store, and dispose of a wide variety of solid material types consisting of multiple radioactive and hazardous waste classes. This includes future Hanford Site activities which will generate new wastes that must be handled as cleanup activities are completed. Solid wastes are typically categorized as transuranic waste, low level waste, low level mixed waste, and hazardous waste. To meet this need the Solid Waste Program has defined its mission as the following - receive, store, treat, decontaminate, and dispose of solid radioactive and nonradioactive dangerous wastes in a safe, cost effective and environmentally compliant manner. This workbook contains the program overview, program baselines and fiscal year work plan for the Solid Waste Program

Ecological Monitoring and Compliance Program Fiscal Year 2003 Report

Energy Technology Data Exchange (ETDEWEB)

Bechtel Nevada

2003-12-01

The Ecological Monitoring and Compliance program, funded through the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office, monitors the ecosystem of the Nevada Test Site and ensures compliance with laws and regulations pertaining to Nevada Test Site biota. This report summarizes the program's activities conducted by Bechtel Nevada during fiscal year 2003.

Fiscal Year 2016 Revegetation Assessment

Energy Technology Data Exchange (ETDEWEB)

Nordstrom, Jenifer B. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2016-11-01

This report summarizes the Fiscal Year (FY) 2016 Revegetation Assessment by Battelle Energy Alliance, LLC. This assessment was conducted to document revegetation efforts at Idaho National Laboratory to verify restoration of disturbed vegetation and soil at various locations occurs as required. This report provides the following information for projects at Idaho National Laboratory completed during FY 2016 that were identified during the National Environmental Policy Act review process as having the potential to disturb soils or vegetation: 1) A summary of all projects identified as having the potential to require revegetation efforts 2) A summary of site disturbance and restoration efforts of each project. For FY 2016, one project required revegetation and sagebrush restoration. For other projects, implementation of best management practices minimized impacts to vegetation and revegetation efforts were not required.

The effects and regulatory mechanism of RIP3 on RGC-5 necroptosis following elevated hydrostatic pressure.

Science.gov (United States)

Shang, Lei; Ding, Wei; Li, Na; Liao, Lvshuang; Chen, Dan; Huang, Jufang; Xiong, Kun

2017-02-06

Necroptosis is a type of regulated cell death that has been implicated in various diseases. Receptor-interacting protein 3 (RIP3), a member of the RIP family, is an important mediator of the necroptotic pathway. Cleavage of RIP3 at Asp328 by caspase-8 abolishes the kinase activity of RIP3, which is critical for necroptosis. Moreover, RIP3 is significantly upregulated during the early stages of acute high intra-ocular pressure and oxygen glucose deprivation. In this study, the effects of RIP3 during elevated hydrostatic pressure (EHP) were investigated and the possible mechanism through which caspase-8 regulated RIP3 cleavage was explored. Flow cytometry analysis revealed that the number of EHP-induced necrotic retinal ganglion cell 5 (RGC-5) cells was reduced after RIP3-knockdown. Furthermore, malondialdehyde (MDA) levels and glycogen phosphorylase (PYGL) activity in normal RGC-5 cells were much higher than those in RIP3-knockdown cells after EHP. EHP-induced RGC-5 necrosis was significantly reduced after treatment with butylated hydroxyanisole (BHA), a reactive oxygen species (ROS) scavenger. MDA levels and PYGL activity were lower in normal RGC-5 cells than those in cells with caspase-8 inhibition after EHP. Western blot analysis demonstrated that the RIP3 cleavage product was upregulated in cells with caspase-8 inhibition. Additionally, flow cytometry analysis revealed that the number of EHP-induced necrotic RGC-5 cells was increased after caspase-8 inhibition. Our results suggested that RGC-5 necroptosis following EHP was mediated by RIP3 through induction of PYGL activity and subsequent ROS accumulation. Thus, caspase-8 may participate in the regulation of RGC-5 necroptosis via RIP3 cleavage. © The Author 2016. Published by Oxford University Press on behalf of the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Hanford Seismic Annual Report and Fourth Quarter Report for Fiscal Year 1999

Energy Technology Data Exchange (ETDEWEB)

AC Rohay; DC Hartshorn; SP Reidel

1999-12-07

Hanford Seismic Monitoring provides an uninterrupted collection of high-quality raw and processed seismic data from the Hanford Seismic Network (HSN) for the U.S. Department of Energy and its contractors. Hanford Seismic Monitoring also locates and identifies sources of seismic activity and monitors changes in the historical pattern of seismic activity at the Hanford Site. The data are compiled, archived, and published for use by the Hanford Site for waste management, Natural Phenomena Hazards assessments, and engineering design and construction. In addition, the seismic monitoring organization works with the Hanford Site Emergency Services Organization to provide assistance in the event of a significant earthquake on the Hanford Site. The HSN and the Eastern Washington Regional Network. (EWRN) consist of 40 individual sensor sites and 15 radio relay sites maintained by the Hanford Seismic Monitoring staff. A major reconfiguration of the HSN was initiated at the end of this quarter and the results will be reported in the first quarter report for next fiscal year (FY2000). For the HSN, there were 390 triggers during the fourth quarter of fiscal year(FY) 1999 on the primary recording system. With the implementation of dual backup systems during the second quarter of the fiscal year and an overall increase observed in sensitivity, a total of 1632 triggers were examined, identified, and processed during this fiscal year. During the fourth quarter, 24 seismic events were located by the HSN within the reporting region of 46 degrees to 47 degrees north latitude and 119 degrees to 120 degrees west longitude 9 were earthquakes in the Columbia River Basalt Group, 2 were earthquakes in the pre-basalt sediments, 10 were earthquakes in the crystalline basement; and 2 were quarry blasts. One earthquake appears to be related to a major geologic structure, 14 earthquakes occurred in known swarm areas, and 7 earthquakes were random occurrences.

Federal Geothermal Research Program Update - Fiscal Year 2001

Energy Technology Data Exchange (ETDEWEB)

Laney, P.T.

2002-08-31

This Federal Geothermal Program Research Update reviews the specific objectives, status, and accomplishments of DOE's Geothermal Program for Federal Fiscal Year (FY) 2001. The information contained in this Research Update illustrates how the mission and goals of the Office of Geothermal Technologies are reflected in each R&D activity. The Geothermal Program, from its guiding principles to the most detailed research activities, is focused on expanding the use of geothermal energy.

Buried Waste Integrated Demonstration fiscal Year 1994 close-out report

International Nuclear Information System (INIS)

Owen, K.J.

1995-07-01

The Buried Waste integrated Demonstration (BWID) supports the applied research, development, demonstration, and evaluation of a multitude of advanced technologies. These technologies are being integrated to form a comprehensive remediation system for the effective and efficient remediation of buried waste. These efforts are identified and coordinated in support of the US Department of Energy Environmental Restoration and Waste Management needs and objectives. BWID works with universities and private industry to develop these technologies, which are being transferred to the private sector for use nationally and internationally. A public participation policy has been established to provide stakeholders with timely and accurate information and meaningful opportunities for involvement in the technology development and demonstration process. To accomplish this mission of identifying technological solutions for remediation deficiencies, the Department of Energy Office of Technology Development initiated BMD at the Idaho National Engineering Laboratory. This report summarizes the activities of the BWID program during Fiscal Year 1994. In Fiscal Year 1995, these activities are transitioning into the Landfill Stabilization Focus Area

Fund for the Improvement of Postsecondary Education Fiscal Year 1983 Awards.

Science.gov (United States)

Fund for the Improvement of Postsecondary Education (ED), Washington, DC.

Information on fiscal year 1983-1984 awards made through the Fund for the Improvement of Postsecondary Education is provided. A list of recipients of new and continuation comprehensive program awards and final year dissemination awards is presented, along with new Mina Shaughnessy Scholars. For each new and continuation recipient, a statement of…

Results on safety research for five years (from fiscal year 1996 to 2000). A field of nuclear fuel cycle

International Nuclear Information System (INIS)

2001-10-01

This safety research carried out by the Japan Nuclear Cycle Development Institute (JNC) for five years ranged from fiscal year 1996 to 2000, was performed according to the safety research basic plan (from fiscal year 1996 to 2000) established on March, 1996 (revised again on May, 2000). This report was arranged on a field on nuclear fuel cycle (all subjects on fields of nuclear fuel facility, environmental radioactivity and radioactive wastes and a subject on nuclear fuel cycle in a field of seismic resistant and probabilistic safety assessment) by combining its research results for five years ranged from 1996 to 2000 fiscal year with general outlines on the safety research basic plan. Here were shown outlines on the safety research basic plan, aims and subjects on safety research at a field of nuclear fuel cycle, a list of survey sheets on safety research result, and survey sheets on safety research results. The survey sheets containing research field, title, organization, researcher name, researching period, names of cooperative organization, using facilities, research outline, research results, established contents, application, and research trends, are ranged to 21 items on nuclear fuel facility, 1 item on seismic resistance, 2 items on probabilistic safety assessment, 8 items on environmental radioactivity, and 20 items on radioactive wastes. (G.K.)

Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation.

Directory of Open Access Journals (Sweden)

Erika Pellegrini

Full Text Available Innate immune receptors NOD1 and NOD2 are activated by bacterial peptidoglycans leading to recruitment of adaptor kinase RIP2, which, upon phosphorylation and ubiquitination, becomes a scaffold for downstream effectors. The kinase domain (RIP2K is a pharmaceutical target for inflammatory diseases caused by aberrant NOD2-RIP2 signalling. Although structures of active RIP2K in complex with inhibitors have been reported, the mechanism of RIP2K activation remains to be elucidated. Here we analyse RIP2K activation by combining crystal structures of the active and inactive states with mass spectrometric characterization of their phosphorylation profiles. The active state has Helix αC inwardly displaced and the phosphorylated Activation Segment (AS disordered, whilst in the inactive state Helix αC is outwardly displaced and packed against the helical, non-phosphorylated AS. Biophysical measurements show that the active state is a stable dimer whilst the inactive kinase is in a monomer-dimer equilibrium, consistent with the observed structural differences at the dimer interface. We conclude that RIP2 kinase auto-phosphorylation is intimately coupled to dimerization, similar to the case of BRAF. Our results will help drug design efforts targeting RIP2 as a potential treatment for NOD2-RIP2 related inflammatory diseases.

Structural snapshots along the reaction pathway of Yersinia pestis RipA, a putative butyryl-CoA transferase

International Nuclear Information System (INIS)

Torres, Rodrigo; Lan, Benson; Latif, Yama; Chim, Nicholas; Goulding, Celia W.

2014-01-01

The crystal structures of Y. pestis RipA mutants were determined to provide insights into the CoA transferase reaction pathway. Yersinia pestis, the causative agent of bubonic plague, is able to survive in both extracellular and intracellular environments within the human host, although its intracellular survival within macrophages is poorly understood. A novel Y. pestis three-gene rip (required for intracellular proliferation) operon, and in particular ripA, has been shown to be essential for survival and replication in interferon γ-induced macrophages. RipA was previously characterized as a putative butyryl-CoA transferase proposed to yield butyrate, a known anti-inflammatory shown to lower macrophage-produced NO levels. RipA belongs to the family I CoA transferases, which share structural homology, a conserved catalytic glutamate which forms a covalent CoA-thioester intermediate and a flexible loop adjacent to the active site known as the G(V/I)G loop. Here, functional and structural analyses of several RipA mutants are presented in an effort to dissect the CoA transferase mechanism of RipA. In particular, E61V, M31G and F60M RipA mutants show increased butyryl-CoA transferase activities when compared with wild-type RipA. Furthermore, the X-ray crystal structures of E61V, M31G and F60M RipA mutants, when compared with the wild-type RipA structure, reveal important conformational changes orchestrated by a conserved acyl-group binding-pocket phenylalanine, Phe85, and the G(V/I)G loop. Binary structures of M31G RipA and F60M RipA with two distinct CoA substrate conformations are also presented. Taken together, these data provide CoA transferase reaction snapshots of an open apo RipA, a closed glutamyl-anhydride intermediate and an open CoA-thioester intermediate. Furthermore, biochemical analyses support essential roles for both the catalytic glutamate and the flexible G(V/I)G loop along the reaction pathway, although further research is required to fully

Structural snapshots along the reaction pathway of Yersinia pestis RipA, a putative butyryl-CoA transferase

Energy Technology Data Exchange (ETDEWEB)

Torres, Rodrigo; Lan, Benson; Latif, Yama; Chim, Nicholas [UC Irvine, 2212 Natural Sciences I, Irvine, CA 92697 (United States); Goulding, Celia W., E-mail: celia.goulding@uci.edu [UC Irvine, 2212 Natural Sciences I, Irvine, CA 92697 (United States); UC Irvine, 2302 Natural Sciences I, Irvine, CA 92697 (United States)

2014-04-01

The crystal structures of Y. pestis RipA mutants were determined to provide insights into the CoA transferase reaction pathway. Yersinia pestis, the causative agent of bubonic plague, is able to survive in both extracellular and intracellular environments within the human host, although its intracellular survival within macrophages is poorly understood. A novel Y. pestis three-gene rip (required for intracellular proliferation) operon, and in particular ripA, has been shown to be essential for survival and replication in interferon γ-induced macrophages. RipA was previously characterized as a putative butyryl-CoA transferase proposed to yield butyrate, a known anti-inflammatory shown to lower macrophage-produced NO levels. RipA belongs to the family I CoA transferases, which share structural homology, a conserved catalytic glutamate which forms a covalent CoA-thioester intermediate and a flexible loop adjacent to the active site known as the G(V/I)G loop. Here, functional and structural analyses of several RipA mutants are presented in an effort to dissect the CoA transferase mechanism of RipA. In particular, E61V, M31G and F60M RipA mutants show increased butyryl-CoA transferase activities when compared with wild-type RipA. Furthermore, the X-ray crystal structures of E61V, M31G and F60M RipA mutants, when compared with the wild-type RipA structure, reveal important conformational changes orchestrated by a conserved acyl-group binding-pocket phenylalanine, Phe85, and the G(V/I)G loop. Binary structures of M31G RipA and F60M RipA with two distinct CoA substrate conformations are also presented. Taken together, these data provide CoA transferase reaction snapshots of an open apo RipA, a closed glutamyl-anhydride intermediate and an open CoA-thioester intermediate. Furthermore, biochemical analyses support essential roles for both the catalytic glutamate and the flexible G(V/I)G loop along the reaction pathway, although further research is required to fully

Environmental restoration and waste management five-year plan, Fiscal years 1994--1998

International Nuclear Information System (INIS)

1993-01-01

The US Department of Energy (DOE) understands that cleaning up the Nation's nuclear-related sites and facilities affects many different segments of the public, ranging from communities near DOE facilities to engineers concerned with developing new technologies to clean up the environment. In an effort to make the Environmental Restoration and Waste Management Five-Year Plan for Fiscal Years (FY) 1994--1998 more responsive to your concerns, DOE invites your comments on the plan. Volume II contains 37 Installation Summaries that provide a synopsis of past, present and future activities of each major installation, and Progress Charts

“I didn't know her, but…”: parasocial mourning of mediated deaths on Facebook RIP pages

DEFF Research Database (Denmark)

Klastrup, Lisbeth

2015-01-01

This article examines the use of six Danish “Rest in Peace” or (RIP) memorial pages. The article focuses on the relation between news media and RIP page use, in relation to general communicative practices on these pages. Based on an analysis of press coverage of the deaths of six young people...... and a close analysis of 1,015 comments extracted from the RIP pages created to memorialize them, it is shown that their deaths attracted considerable media attention, as did the RIP pages themselves. Comment activity seem to reflect the news stories in the way the commenters refer to the context of death...... and the emotional distress they experience, but mainly comments on the RIP pages are conventional expressions of sympathy and “RIP” wishes. The article concludes that public RIP pages might be understood as virtual spontaneous shrines, affording an emerging practice of “RIP-ing.”...

2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. The Citadel. Sector: Four-Year Colleges and Universities

Science.gov (United States)

South Carolina Commission on Higher Education, 2005

2005-01-01

This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. Lander University. Sector: Four-Year Colleges and Universities

Science.gov (United States)

South Carolina Commission on Higher Education, 2005

2005-01-01

This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. Winthrop University. Sector: Four-Year Colleges and Universities

Science.gov (United States)

South Carolina Commission on Higher Education, 2005

2005-01-01

This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

Deployment summary: Fiscal years 1995-2000 [USDOE Office of International Programs

International Nuclear Information System (INIS)

2000-01-01

This publication summarizes the progress made by the Office of International Programs (IP) in deploying innovative technologies for the environmental remediation of the DOE complex and for sites of its international collaborators for fiscal years 1995 through 2000

Deployment summary: Fiscal years 1995-2000 [USDOE Office of International Programs

Energy Technology Data Exchange (ETDEWEB)

None

2000-07-01

This publication summarizes the progress made by the Office of International Programs (IP) in deploying innovative technologies for the environmental remediation of the DOE complex and for sites of its international collaborators for fiscal years 1995 through 2000.

FMCSA safety program effectiveness measurement : Intervention Model in fiscal year 2007

Science.gov (United States)

2011-04-01

This report presents results from FMCSAs Roadside Intervention Model for fiscal year 2007. The model estimates the number of crashes avoided, as well as injuries avoided and lives saved, as a result of the Agencys roadside inspection program. T...

2-HG Inhibits Necroptosis by Stimulating DNMT1-Dependent Hypermethylation of the RIP3 Promoter

Directory of Open Access Journals (Sweden)

Zhentao Yang

2017-05-01

Full Text Available 2-hydroxyglutarate-(2-HG-mediated inhibition of TET2 activity influences DNA hypermethylation in cells harboring mutations of isocitrate dehydrogenases 1 and 2 (IDH1/2. Here, we show that 2-HG also regulates DNA methylation mediated by DNA methyltransferase 1 (DNMT1. DNMT1-dependent hypermethylation of the RIP3 promoter occurred in both IDH1 R132Q knockin mutant mouse embryonic fibroblast (MEFs and 2-HG-treated wild-type (WT MEFs. We found that 2-HG bound to DNMT1 and stimulated its association with the RIP3 promoter, inducing hypermethylation that reduces RIP3 protein and consequently impaired RIP3-dependent necroptosis. In human glioma samples, RIP3 protein levels correlated negatively with IDH1 R132H levels. Furthermore, ectopic expression of RIP3 in transformed IDH1-mutated MEFs inhibited the growth of tumors derived from these cells following transplantation into nude mice. Thus, our research sheds light on a mechanism of 2-HG-induced DNA hypermethylation and suggests that impaired necroptosis contributes to the tumorigenesis driven by IDH1/2 mutations.

RIP3 attenuates the pancreatic damage induced by deletion of ATG7.

Science.gov (United States)

Zhou, Xiaodong; Xie, Li; Xia, Leizhou; Bergmann, Frank; Büchler, Markus W; Kroemer, Guido; Hackert, Thilo; Fortunato, Franco

2017-07-13

Invalidation of pancreatic autophagy entails pancreatic atrophy, endocrine and exocrine insufficiency and pancreatitis. The aim of this study was to investigate whether depletion of Rip3, which is involved in necroptotic signaling, may attenuate the pancreatic atrophy and pancreatitis resulting from autophagy inhibition. Autophagy and necroptosis signaling were evaluated in mice lacking expression of Rip3 in all organs and Atg7 in the pancreas. Acinar cell death, inflammation and fibrosis were evaluated by using of a compendium of immunofluorescence methods and immunoblots. Mice deficient for pancreatic Atg7 developed acute pancreatitis, which progressed to chronic pancreatitis. This phenotype reduces autophagy, increase apoptosis and necroptosis, inflammation and fibrosis, as well as premature death of the animals. Knockout of Rip3 exacerbated the apoptotic death of acinar cells, increased tissue damage, reduced macrophage infiltration and further accelerated the death of the mice with Atg7-deficient pancreas. The pancreatic degeneration induced by autophagy inhibition was exacerbated by Rip3 deletion.

The transcriptional co-factor RIP140 regulates mammary gland development by promoting the generation of key mitogenic signals.

Science.gov (United States)

Nautiyal, Jaya; Steel, Jennifer H; Mane, Meritxell Rosell; Oduwole, Olayiwola; Poliandri, Ariel; Alexi, Xanthippi; Wood, Nicholas; Poutanen, Matti; Zwart, Wilbert; Stingl, John; Parker, Malcolm G

2013-03-01

Nuclear receptor interacting protein (Nrip1), also known as RIP140, is a co-regulator for nuclear receptors that plays an essential role in ovulation by regulating the expression of the epidermal growth factor-like family of growth factors. Although several studies indicate a role for RIP140 in breast cancer, its role in the development of the mammary gland is unclear. By using RIP140-null and RIP140 transgenic mice, we demonstrate that RIP140 is an essential factor for normal mammary gland development and that it functions by mediating oestrogen signalling. RIP140-null mice exhibit minimal ductal elongation with no side-branching, whereas RIP140-overexpressing mice show increased cell proliferation and ductal branching with age. Tissue recombination experiments demonstrate that RIP140 expression is required in both the mammary epithelial and stromal compartments for ductal elongation during puberty and that loss of RIP140 leads to a catastrophic loss of the mammary epithelium, whereas RIP140 overexpression augments the mammary basal cell population and shifts the progenitor/differentiated cell balance within the luminal cell compartment towards the progenitors. For the first time, we present a genome-wide global view of oestrogen receptor-α (ERα) binding events in the developing mammary gland, which unravels 881 ERα binding sites. Unbiased evaluation of several ERα binding sites for RIP140 co-occupancy reveals selectivity and demonstrates that RIP140 acts as a co-regulator with ERα to regulate directly the expression of amphiregulin (Areg), the progesterone receptor (Pgr) and signal transducer and activator of transcription 5a (Stat5a), factors that influence key mitogenic pathways that regulate normal mammary gland development.

Radioactive wastes management in fiscal year 1983 in the fuel reprocessing plant

International Nuclear Information System (INIS)

1985-01-01

In the nuclear fuel reprocessing plant of Power Reactor and Nuclear Fuel Development Corporation, the releases of radioactive gaseous and liquid wastes are so managed not to exceed the respective objective release levels. Of the radioactive liquid wastes, the high level concentrated wastes are stored in tanks and the low level wastes are stored in tanks or asphalt solidified. For radioactive solid wastes, high level solid wastes are stored in casks, low level solid wastes and asphalt solids in drums etc. The releases of radioactive gaseous and liquid wastes in the fiscal year 1983 were below the objective release levels. The radioactive wastes management in the fuel reprocessing plant in fiscal year 1983 is given in tables, the released quantities, the stored quantities, etc. (Mori, K.)

Annual Report of the Integrated Status and Effectiveness Monitoring Program: Fiscal Year 2008

Energy Technology Data Exchange (ETDEWEB)

Terraqua, Inc. (Wauconda, WA)

2009-07-20

This document was created as an annual report detailing the accomplishments of the Integrated Status and Effectiveness Monitoring Program (ISEMP) in the Upper Columbia Basin in fiscal year 2008. The report consists of sub-chapters that reflect the various components of the program. Chapter 1 presents a report on programmatic coordination and accomplishments, and Chapters 2 through 4 provide a review of how ISEMP has progressed during the 2008 fiscal year in each of the pilot project subbasins: the John Day (Chapter 2), Wenatchee/Entiat (Chapter 3) and Salmon River (Chapter 4). Chapter 5 presents a report on the data management accomplishments in 2008.

2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. Clemson University. Sector: Research Institutions

Science.gov (United States)

South Carolina Commission on Higher Education, 2005

2005-01-01

This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

Horonobe Underground Research Laboratory project. Investigation report for the 2006 fiscal year

International Nuclear Information System (INIS)

Matsui, Hiroya; Nakayama, Masashi; Sanada, Hiroyuki

2008-05-01

The Horonobe Underground Research Laboratory is planned to extend over a period of 20 years. The investigations will be conducted in three phases, namely 'Phase 1: Surface-based investigations', 'Phase 2: Construction Phase' (investigations during construction of the underground facilities) and 'Phase 3: Operation phase' (research in the underground facilities). This report summarizes the results of the investigations for the 2006 fiscal year (2006/2007), the second year of the Phase 2 investigations. The investigations, which are composed of 'Geoscientific research' and 'R and D on the geological disposal of high-level radioactive waste (HLW)', were carried out according to 'Horonobe Underground Research Laboratory Project Investigation Program for the 2006 Fiscal Year'. The results of these investigations, along with the results which were obtained in other departments of Japan Atomic Energy Agency (JAEA), are properly offered to the implementations and the safety regulations. JAEA proceeded with the project in, collaboration with experts from domestic and overseas research organisation. (author)

Horonobe Underground Research Laboratory project. Investigation report for the 2007 fiscal year

International Nuclear Information System (INIS)

Nakayama, Masashi; Sanada, Hiroyuki; Sugita, Yutaka

2008-09-01

The Horonobe Underground Research Laboratory Project is planned to extend over a period of 20 years. The investigations will be conducted in three phases, namely 'Phase 1: Surface-based investigations', 'Phase 2: Construction Phase' (investigations during construction of the underground facilities) and 'Phase 3: Operation phase' (research in the underground facilities). This report summarizes the results of the investigations for the 2007 fiscal year (2007/2008), the 3rd year of the Phase 2 investigations. The investigations, which are composed of 'Geoscientific research' and 'R and D on the geological disposal of high-level radioactive waste (HLW)', were carried out according to 'Horonobe Underground Research Laboratory Project Investigation Program for the 2007 Fiscal Year'. The results of these investigations, along with the results which were obtained in other departments of Japan Atomic Energy Agency (JAEA), are properly offered to the implementations and the safety regulations. JAEA proceeded with the project in collaboration with experts from domestic and overseas research organisation. (author)

Horonobe Underground Research Laboratory project investigation report for the 2008 fiscal year

International Nuclear Information System (INIS)

Nakayama, Masashi; Sano, Michiaki; Sanada, Hiroyuki; Sugita, Yutaka

2009-11-01

The Horonobe Underground Research Laboratory Project is planned to extend over a period 20 years. The investigations will be conducted in three phases, namely 'Phase 1: Surface-based investigations' 'Phase 2: Construction Phase' (investigations during construction of the underground facilities) and 'Phase 3: Operation phase' (research in the underground facilities). This report summarizes the results of the investigations for the 2008 fiscal year (2008/2009), the 4th year of the Phase 2 investigations. The investigations, which are composed of 'Geoscientific research' and 'R and D on geological disposal technology', were carried out according to 'Horonobe Underground Research Laboratory Project Investigation Program for the 2008 Fiscal year'. The results of these investigations, along with the results which were obtained in other departments of Japan Atomic Energy Agency (JAEA), are properly offered to the implementations and the safety regulations. For the sake of this, JAEA has proceeded with the project in collaboration with experts from domestic and overseas research organisations. (author)

Rip3 knockdown rescues photoreceptor cell death in blind pde6c zebrafish.

Science.gov (United States)

Viringipurampeer, I A; Shan, X; Gregory-Evans, K; Zhang, J P; Mohammadi, Z; Gregory-Evans, C Y

2014-05-01

Achromatopsia is a progressive autosomal recessive retinal disease characterized by early loss of cone photoreceptors and later rod photoreceptor loss. In most cases, mutations have been identified in CNGA3, CNGB3, GNAT2, PDE6C or PDE6H genes. Owing to this genetic heterogeneity, mutation-independent therapeutic schemes aimed at preventing cone cell death are very attractive treatment strategies. In pde6c(w59) mutant zebrafish, cone photoreceptors expressed high levels of receptor-interacting protein kinase 1 (RIP1) and receptor-interacting protein kinase 3 (RIP3) kinases, key regulators of necroptotic cell death. In contrast, rod photoreceptor cells were alternatively immunopositive for caspase-3 indicating activation of caspase-dependent apoptosis in these cells. Morpholino gene knockdown of rip3 in pde6c(w59) embryos rescued the dying cone photoreceptors by inhibiting the formation of reactive oxygen species and by inhibiting second-order neuron remodelling in the inner retina. In rip3 morphant larvae, visual function was restored in the cones by upregulation of the rod phosphodiesterase genes (pde6a and pde6b), compensating for the lack of cone pde6c suggesting that cones are able to adapt to their local environment. Furthermore, we demonstrated through pharmacological inhibition of RIP1 and RIP3 activity that cone cell death was also delayed. Collectively, these results demonstrate that the underlying mechanism of cone cell death in the pde6c(w59) mutant retina is through necroptosis, whereas rod photoreceptor bystander death occurs through a caspase-dependent mechanism. This suggests that targeting the RIP kinase signalling pathway could be an effective therapeutic intervention in retinal degeneration patients. As bystander cell death is an important feature of many retinal diseases, combinatorial approaches targeting different cell death pathways may evolve as an important general principle in treatment.

RIP studies at AREVA: R&D and applications for Niger and Canada projects

International Nuclear Information System (INIS)

Ling, Y.; Durupt, N.; Banton, N.

2010-01-01

Cominak in Niger owns a large stock of high grade fines which cumulated originally from underground mining discharge water. This ore is too fine to be treated with the current process because it readily blocks the cloths of the belt filters. Cominak plans to build a Resin-In-Pulp (RIP) plant. The RIP technology permits to recover U values without filtration. Some bench scale studies (at AREVA-SEPA) and two trial campaigns (on site) had been successfully conducted to implement the RIP process, which further allows, from economic point of view, a positive feasibility evaluation. As part of the Kiggavik Project managed by Areva Resources Canada (ARC), AREVA-SEPA is also being actively involved in developing a practical, cost-effective and environmentally sound process flowsheet. RIP technology has drawn significant attention due to the relatively low water consumption and capital cost. SEPA's experience with RIP technology together with the newer and better-performance resins makes this technology a viable choice. Three pilot campaigns have been accomplished at SEPA, which is believed to be of great help to reduce technical risk as well as capital risk in the decision making for Kiggavik project. (author)

Development Achievements at Pittsburg State University for Fiscal Year 1988.

Science.gov (United States)

Smoot, Joseph G.

The development report for Pittsburg State University's (PSU) fiscal year 1988 is presented. The most important objective of PSU's development program is to provide funding beyond the state support in order to distinguish the university among its U.S. peers. Chapters include an overview of FY 1988 development activities, the Annual Fund, the…

Accountability report. Fiscal Year 1996, Volume 2

International Nuclear Information System (INIS)

1997-01-01

This report consolidates several performance-related reports into a single financial management report. Information in this report includes information previously reported in the following documents: (1) US Nuclear Regulatory Commission's (NRC's) annual financial statement, (2) NRC Chairman's annual report to the President and the Congress, and (3) NRC Chairman's semiannual report to Congress on management decisions and final actions on Office of Inspector General audit recommendations. This report also contains performance measures. The report is organized into the following subtopics: information about the US NRC, program performance, management accountability, and the audited financial statement for Fiscal Year 1996. 19 figs., 4 tabs

75 FR 71137 - Announcement of Funding Awards for the HOPE VI Revitalization Grant Program for Fiscal Year 2009

Science.gov (United States)

2010-11-22

... Awards for the HOPE VI Revitalization Grant Program for Fiscal Year 2009 AGENCY: Office of the Assistant... the Fiscal Year 2009 (FY 2009) Notice of Funding Availability (NOFA) for the HOPE VI Revitalization.... FOR FURTHER INFORMATION CONTACT: For questions concerning the HOPE VI Revitalization grant awards...

78 FR 18966 - Publication of Fiscal Year 2012 Service Contract Inventory

Science.gov (United States)

2013-03-28

... COURT SERVICES AND OFFENDER SUPERVISION AGENCY FOR THE DISTRICT OF COLUMBIA Publication of Fiscal Year 2012 Service Contract Inventory AGENCY: Court Services and Offender Supervision Agency for the District of Columbia. ACTION: Notice of Public Availability of FY 2012 Service Contract Inventory. SUMMARY...

Review of the President's Fiscal Year 2009 Budget Request for the Defense Health Program's Private Sector Care Budget Activity Group

National Research Council Canada - National Science Library

Fantone, Denise M; Pickup, Sharon

2008-01-01

The Conference Report accompanying the Fiscal Year 2008 Department of Defense Appropriations bill directed us to review the President's fiscal year 2009 budget request for the Defense Health Program's...

Horonobe Underground Research Laboratory project. Investigation report for the 2010 fiscal year

International Nuclear Information System (INIS)

Nakayama, Masashi; Sawada, Sumiyuki; Sugita, Yutaka

2011-09-01

The Horonobe Underground Research Laboratory Project is planned to extend over a period 20 years. The investigations will be conducted in three phases, namely 'Phase 1: Surface-based investigations', 'Phase 2: Construction Phase' (investigations during construction of the underground facilities) and 'Phase 3: Operation phase' (research in the underground facilities). This report summarizes the results of the investigations for the 2010 fiscal year (2010/2011). The investigations, which are composed of 'Geoscientific research' and 'R and D on geological disposal technology', were carried out according to 'Horonobe Underground Research Laboratory Project Investigation Program for the 2010 Fiscal year'. The results of these investigations, along with the results which were obtained in other departments of Japan Atomic Energy Agency (JAEA), are properly offered to the implementations and the safety regulations. For the sake of this, JAEA has proceeded with the project in collaboration with experts from domestic and overseas research organisations. (author)

Research plan on geosphere stability for long-term isolation of radioactive waste. Scientific programme for fiscal year 2016

International Nuclear Information System (INIS)

Ishimaru, Tsuneari; Yasue, Kenichi; Kokubu, Yoko; Niwa, Masakazu; Asamori, Koichi; Watanabe, Takahiro; Yokoyama, Tatsunori; Fujita, Natsuko; Shimizu, Mayuko; Hama, Yuki

2016-08-01

This report is a plan of research and development (R and D) on geosphere stability for long-term isolation of high-level radioactive waste (HLW) in Japan Atomic Energy Agency, in fiscal year 2016. The objectives and contents in fiscal year 2016 are described in detail based on the outline of 7 years plan (fiscal years 2015-2021). Background of this research is clarified with the necessity and the significance for site investigation and safety assessment, and the past progress in this report. In addition, the plan framework is structured into the following categories: (1) Development and systematization of investigation techniques, (2) Development of models for long-term estimation and effective assessment, (3) Development of dating techniques. (author)

Structural insights into RipC, a putative citrate lyase β subunit from a Yersinia pestis virulence operon

International Nuclear Information System (INIS)

Torres, Rodrigo; Chim, Nicholas; Sankaran, Banumathi; Pujol, Céline; Bliska, James B.; Goulding, Celia W.

2011-01-01

Comparison of the 2.45 Å resolution crystal structure of homotrimeric RipC, a putative citrate lyase β subunit from Y. pestis, with structural homologs reveals conserved RipC residues that are implicated in CoA binding. Yersinia pestis remains a threat, with outbreaks of plague occurring in rural areas and its emergence as a weapon of bioterrorism; thus, an improved understanding of its various pathogenicity pathways is warranted. The rip (required for intracellular proliferation) virulence operon is required for Y. pestis survival in interferon-γ-treated macrophages and has been implicated in lowering macrophage-produced nitric oxide levels. RipC, one of three gene products from the rip operon, is annotated as a citrate lyase β subunit. Furthermore, the Y. pestis genome lacks genes that encode citrate lyase α and γ subunits, suggesting a unique functional role of RipC in the Y. pestisrip-mediated survival pathway. Here, the 2.45 Å resolution crystal structure of RipC revealed a homotrimer in which each monomer consists of a (β/α) 8 TIM-barrel fold. Furthermore, the trimeric state was confirmed in solution by size-exclusion chromatography. Through sequence and structure comparisons with homologous proteins, it is proposed that RipC is a putative CoA- or CoA-derivative binding protein

Economic impact study of the Uranium Mill Tailings Remedial Action Project in Colorado: Colorado State fiscal year 1994. Revision 1

International Nuclear Information System (INIS)

1994-12-01

The Colorado economic impact study summarizes employment and economic benefits to the state from activities associated with the Uranium Mill Tailings Remedial Action (UMTRA) Project during Colorado state fiscal year 1994 (1 July 1993 through 30 June 1994). To capture employment information, a questionnaire was distributed to subcontractor employees at the active UMTRA Project sites of Grand Junction, Naturita, Gunnison, and Rifle, Colorado. Economic data were requested from each site prime subcontractor, as well as from the Remedial Action Contractor. Information on wages, taxes, and subcontract expenditures in combination with estimates and economic multipliers is used to estimate the dollar economic benefits to Colorado during the state fiscal year. Finally, the fiscal year 1994 estimates are compared to fiscal year 1993 employment and economic information

Confronting dark energy models mimicking ΛCDM epoch with observational constraints: Future cosmological perturbations decay or future Rip?

International Nuclear Information System (INIS)

Astashenok, Artyom V.; Odintsov, Sergei D.

2013-01-01

We confront dark energy models which are currently similar to ΛCDM theory with observational data which include the SNe data, matter density perturbations and baryon acoustic oscillations data. DE cosmology under consideration may evolve to Big Rip, type II or type III future singularity, or to Little Rip or Pseudo-Rip universe. It is shown that matter perturbations data define more precisely the possible deviation from ΛCDM model than consideration of SNe data only. The combined data analysis proves that DE models under consideration are as consistent as ΛCDM model. We demonstrate that growth of matter density perturbations may occur at sufficiently small background density but still before the possible disintegration of bound objects (like clusters of galaxies, galaxies, etc.) in Big Rip, type III singularity, Little Rip or Pseudo-Rip universe. This new effect may bring the future universe to chaotic state well before disintegration or Rip.

Fiscal Year 2015 Site Sustainability Plan

Energy Technology Data Exchange (ETDEWEB)

Witt, Monica Rene [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2015-03-16

Los Alamos National Laboratory is taking action to operate as a living laboratory for sustainable solutions in buildings, climate, energy, purchasing, transportation, waste, and water. LANL prepared the fiscal year (FY) 2015 Site Sustainability Plan (SSP) to describe progress towards the goals established in the SSPP. In addition, per the requirements of DOE Order 436.1, Departmental Sustainability, Los Alamos National Laboratory (LANL) uses its International Organization for Standardization (ISO) 14001:2004 certified Environmental Management System (EMS) to establish objectives to improve compliance, reduce environmental impacts, increase operational capacity, and meet long-term sustainability goals. The goals of the 2015 SSP are fully integrated into LANL’s institutional environmental objectives under the EMS and its Long-Term Strategy for Environmental Stewardship & Sustainability (LTSESS).

2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. Francis Marion University. Sector: Four-Year Colleges and Universities

Science.gov (United States)

South Carolina Commission on Higher Education, 2005

2005-01-01

This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. College of Charleston. Sector: Four-Year Colleges and Universities

Science.gov (United States)

South Carolina Commission on Higher Education, 2005

2005-01-01

This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. Coastal Carolina University. Sector: Four-Year Colleges and Universities

Science.gov (United States)

South Carolina Commission on Higher Education, 2005

2005-01-01

This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

In silico reversal of repeat-induced point mutation (RIP identifies the origins of repeat families and uncovers obscured duplicated genes

Directory of Open Access Journals (Sweden)

Hane James K

2010-11-01

Full Text Available Abstract Background Repeat-induced point mutation (RIP is a fungal genome defence mechanism guarding against transposon invasion. RIP mutates the sequence of repeated DNA and over time renders the affected regions unrecognisable by similarity search tools such as BLAST. Results DeRIP is a new software tool developed to predict the original sequence of a RIP-mutated region prior to the occurrence of RIP. In this study, we apply deRIP to the genome of the wheat pathogen Stagonospora nodorum SN15 and predict the origin of several previously uncharacterised classes of repetitive DNA. Conclusions Five new classes of transposon repeats and four classes of endogenous gene repeats were identified after deRIP. The deRIP process is a new tool for fungal genomics that facilitates the identification and understanding of the role and origin of fungal repetitive DNA. DeRIP is open-source and is available as part of the RIPCAL suite at http://www.sourceforge.net/projects/ripcal.

Fiscal Year 2001 Tank Characterization Technical Sampling Basis and Waste Information Requirements Document

International Nuclear Information System (INIS)

ADAMS, M.R.

2000-01-01

The Fiscal Year 2001 Tank Characterization Technical Sampling Basis and Waste Information Requirements Document (TSB-WIRD) has the following purposes: (1) To identify and integrate sampling and analysis needs for fiscal year (FY) 2001 and beyond. (2) To describe the overall drivers that require characterization information and to document their source. (3) To describe the process for identifying, prioritizing, and weighting issues that require characterization information to resolve. (4) To define the method for determining sampling priorities and to present the sampling priorities on a tank-by-tank basis. (5) To define how the characterization program is going to satisfy the drivers, close issues, and report progress. (6)To describe deliverables and acceptance criteria for characterization deliverables

Report: FISMA - Fiscal Year 2004 Status of EPA’s Computer Security Program

Science.gov (United States)

Report #2004-S-00007, September 30, 2004. This report synopsizes the results of information technology security work the U.S. Environmental Protection Agency’s Office of Inspector General (OIG) performed during Fiscal Year (FY) 2004.

75 FR 22095 - USDA Reassigns Domestic Cane Sugar Allotments and Increases the Fiscal Year 2010 Raw Sugar Tariff...

Science.gov (United States)

2010-04-27

... USDA Reassigns Domestic Cane Sugar Allotments and Increases the Fiscal Year 2010 Raw Sugar Tariff-Rate... announced a reassignment of surplus sugar under domestic cane sugar allotments of 200,000 short tons raw value (STRV) to imports, and increased the fiscal year (FY) 2010 raw sugar tariff-rate quota (TRQ) by...

75 FR 38764 - USDA Reassigns Domestic Cane Sugar Allotments and Increases the Fiscal Year 2010 Raw Sugar Tariff...

Science.gov (United States)

2010-07-06

... USDA Reassigns Domestic Cane Sugar Allotments and Increases the Fiscal Year 2010 Raw Sugar Tariff-Rate... announced a reassignment of surplus sugar under domestic cane sugar allotments of 300,000 short tons raw value (STRV) to imports, and increased the fiscal year (FY) 2010 raw sugar tariff-rate quota (TRQ) by...

76 FR 20305 - USDA Reassigns Domestic Cane Sugar Allotments and Increases the Fiscal Year 2011 Raw Sugar Tariff...

Science.gov (United States)

2011-04-12

... USDA Reassigns Domestic Cane Sugar Allotments and Increases the Fiscal Year 2011 Raw Sugar Tariff-Rate... announced a reassignment of surplus sugar under domestic cane sugar allotments of 325,000 short tons raw value (STRV) to imports, and increased the fiscal year (FY) 2011 raw sugar tariff-rate quota (TRQ) by...

The phytopathogenic virulent effector protein RipI induces apoptosis in budding yeast Saccharomyces cerevisiae.

Science.gov (United States)

Deng, Meng-Ying; Sun, Yun-Hao; Li, Pai; Fu, Bei; Shen, Dong; Lu, Yong-Jun

2016-10-01

Virulent protein toxins secreted by the bacterial pathogens can cause cytotoxicity by various molecular mechanisms to combat host cell defense. On the other hand, these proteins can also be used as probes to investigate the defense pathway of host innate immunity. Ralstonia solanacearum, one of the most virulent bacterial phytopathogens, translocates more than 70 effector proteins via type III secretion system during infection. Here, we characterized the cytotoxicity of effector RipI in budding yeast Saccharomyce scerevisiae, an alternative host model. We found that over-expression of RipI resulted in severe growth defect and arginine (R) 117 within the predicted integrase motif was required for inhibition of yeast growth. The phenotype of death manifested the hallmarks of apoptosis. Our data also revealed that RipI-induced apoptosis was independent of Yca1 and mitochondria-mediated apoptotic pathways because Δyca1 and Δaif1 were both sensitive to RipI as compared with the wild type. We further demonstrated that RipI was localized in the yeast nucleus and the N-terminal 1-174aa was required for the localization. High-throughput RNA sequencing analysis showed that upon RipI over-expression, 101 unigenes of yeast ribosome presented lower expression level, and 42 GO classes related to the nucleus or recombination were enriched with differential expression levels. Taken together, our data showed that a nuclear-targeting effector RipI triggers yeast apoptosis, potentially dependent on its integrase function. Our results also provided an alternative strategy to dissect the signaling pathway of cytotoxicity induced by the protein toxins. Copyright © 2016 Elsevier Ltd. All rights reserved.

SimBa: An Efficient Tool for Approximating Rips-Filtration Persistence via Simplicial Batch-Collapse

OpenAIRE

Dey, Tamal K.; Shi, Dayu; Wang, Yusu

2016-01-01

In topological data analysis, a point cloud data P extracted from a metric space is often analyzed by computing the persistence diagram or barcodes of a sequence of Rips complexes built on $P$ indexed by a scale parameter. Unfortunately, even for input of moderate size, the size of the Rips complex may become prohibitively large as the scale parameter increases. Starting with the Sparse Rips filtration introduced by Sheehy, some existing methods aim to reduce the size of the complex so as to ...

Index of Reports and Testimony: Fiscal Year 1991.

Science.gov (United States)

1991-12-01

74FS, Apr. 24 U.S.-Mexico Trade: Some U.S. Wood Furniture Firms Relocated From Los Angeles Area to Mexico GAO NSIAD-91-191 Apr. 24 El Comercio Entre U.S...Testimony: Fiscal Year 1991 El Comercio Entry Los EE. UU. y Mexico: Informacion acerca de la reglamentacion ambiental y su cumplimiento GAO NSIAi)-91-227SV...Considerations GAO/RCED-91-240 Sept. 17 Air Traffic Control: FAA’s Transition of Communications System to Digital Technology GAO/IMTEC-91-77FS Sept. 26

Annual report of Technical Development Division of the Tono Geoscience Center, PNC in 1996 fiscal year

International Nuclear Information System (INIS)

1997-04-01

This is a report collected working results of research and development conducted at Technical Development Division of the Tono Geoscience Center, PNC (Power Reactor and Nuclear Fuel Development Corporation) in 1996 fiscal year. In this fiscal year, Ore Bed Analysis and Evaluation Group entered into this division by changing name of Resource Analysis and Evaluation Group, which was shared to conduct some actions such as survey of resource information, analysis of potential, evaluation of ore bed, and so forth. The other conducted works were same as those in last fiscal year. Beside them, as taking the Monju reactor accident on December 8, 1995 an opportunity, safety management of facility was reconsidered as the most important item, preparation of the mining facilities such as renewal of lifting winder in vertical road for survey, new construction of general management building, preparation around the precipitation pond, and so on were executed, as a response to normal work for the yearly elapsed change in the Tono Mine. (G.K.)

Deep Vadose Zone–Applied Field Research Initiative Fiscal Year 2012 Annual Report

Energy Technology Data Exchange (ETDEWEB)

Wellman, Dawn M.; Truex, Michael J.; Johnson, Timothy C.; Bunn, Amoret L.; Golovich, Elizabeth C.

2013-03-14

This annual report describes the background of the Deep Vadose Zone-Applied Field Research Initiative, and some of the programmatic approaches and transformational technologies in groundwater and deep vadose zone remediation developed during fiscal year 2012.

Repository Integration Program: RIP performance assessment and strategy evaluation model theory manual and user's guide

International Nuclear Information System (INIS)

1995-11-01

This report describes the theory and capabilities of RIP (Repository Integration Program). RIP is a powerful and flexible computational tool for carrying out probabilistic integrated total system performance assessments for geologic repositories. The primary purpose of RIP is to provide a management tool for guiding system design and site characterization. In addition, the performance assessment model (and the process of eliciting model input) can act as a mechanism for integrating the large amount of available information into a meaningful whole (in a sense, allowing one to keep the ''big picture'' and the ultimate aims of the project clearly in focus). Such an integration is useful both for project managers and project scientists. RIP is based on a '' top down'' approach to performance assessment that concentrates on the integration of the entire system, and utilizes relatively high-level descriptive models and parameters. The key point in the application of such a ''top down'' approach is that the simplified models and associated high-level parameters must incorporate an accurate representation of their uncertainty. RIP is designed in a very flexible manner such that details can be readily added to various components of the model without modifying the computer code. Uncertainty is also handled in a very flexible manner, and both parameter and model (process) uncertainty can be explicitly considered. Uncertainty is propagated through the integrated PA model using an enhanced Monte Carlo method. RIP must rely heavily on subjective assessment (expert opinion) for much of its input. The process of eliciting the high-level input parameters required for RIP is critical to its successful application. As a result, in order for any project to successfully apply a tool such as RIP, an enormous amount of communication and cooperation must exist between the data collectors, the process modelers, and the performance. assessment modelers

Hanford Site Groundwater Monitoring for Fiscal Year 2005

Energy Technology Data Exchange (ETDEWEB)

Hartman, Mary J.; Morasch, Launa F.; Webber, William D.

2006-02-28

This report is one of the major products and deliverables of the Groundwater Remediation and Closure Assessment Projects detailed work plan for FY 2006, and reflects the requirements of The Groundwater Performance Assessment Project Quality Assurance Plan (PNNL-15014). This report presents the results of groundwater and vadose zone monitoring and remediation for fiscal year 2005 on the U.S. Department of Energy's Hanford Site, Washington. The most extensive contaminant plumes in groundwater are tritium, iodine-129, and nitrate, which all had multiple sources and are very mobile in groundwater. The largest portions of these plumes are migrating from the central Hanford Site to the southeast, toward the Columbia River. Carbon tetrachloride and associated organic constituents form a relatively large plume beneath the west-central part of the Hanford Site. Hexavalent chromium is present in plumes beneath the reactor areas along the river and beneath the central part of the site. Strontium-90 exceeds standards beneath all but one of the reactor areas. Technetium-99 and uranium plumes exceeding standards are present in the 200 Areas. A uranium plume underlies the 300 Area. Minor contaminant plumes with concentrations greater than standards include carbon-14, cesium-137, cis-1,2-dichloroethene, cyanide, fluoride, plutonium, and trichloroethene. Monitoring for the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 is conducted in 11 groundwater operable units. The purpose of this monitoring is to define and track plumes and to monitor the effectiveness of interim remedial actions. Interim groundwater remediation in the 100 Areas continued with the goal of reducing the amount of chromium (100-K, 100-D, and 100-H) and strontium-90 (100-N) reaching the Columbia River. The objective of two interim remediation systems in the 200 West Area is to prevent the spread of carbon tetrachloride and technetium-99/uranium plumes. Resource Conservation and

Accountability report. Fiscal Year 1996, Volume 2

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-05-01

This report consolidates several performance-related reports into a single financial management report. Information in this report includes information previously reported in the following documents: (1) US Nuclear Regulatory Commission`s (NRC`s) annual financial statement, (2) NRC Chairman`s annual report to the President and the Congress, and (3) NRC Chairman`s semiannual report to Congress on management decisions and final actions on Office of Inspector General audit recommendations. This report also contains performance measures. The report is organized into the following subtopics: information about the US NRC, program performance, management accountability, and the audited financial statement for Fiscal Year 1996. 19 figs., 4 tabs.

Potentiometric-level monitoring program, Mississippi and Louisiana: Annual status report for fiscal year 1985

International Nuclear Information System (INIS)

1986-10-01

Potentiometric-level data presented in this report were collected at 82 wells in Mississippi and Louisiana from October 1984 through September 1985. These wells are located near Richton and Cypress Creek Domes in Mississippi and Vacherie dome in Louisiana. Three wells were reinstated to the program during this period. Two previously destroyed wells were deleted from the program. Protective barriers were installed around 26 shallow borings in Mississippi. Cursory analysis of the data in Mississippi indicated minimal, if any, change in potentiometric level during the past year in the Citronelle, Hattiesburg, Cockfield, Sparta, and Wilcox Formations. A slight decline, on the order of 0.3 meter (1 foot), occurred during the past year in well MCCG-1, which is screened in the caprock of Cypress Creek Dome. The potentiometric level in well MRIG-9, in the caprock of Richton Dome, stabilized during fiscal year 1985 following 5 years of increase. The Catahoula Formation experienced a continuing decline of about 0.3 meter/year (1 foot/year). Well MH-5C, screened in the Cook Mountain Formation, showed a continuing, long-term, upward trend on the order of 1.5 meters (4.9 feet) during the past year. The potentiometric level of well MH-8C, screened in the Cook Mountain Formation, stabilized during fiscal year 1985, following 5 years of large annual increases. Wells screened in the Austin Formation in Louisiana showed a downward trend of 0.3 to 1 meter (1 to 3.3 feet) during fiscal year 1985. Other formations in Louisiana generally showed no change in potentiometric level

Annual report procurement and logistics management center Sandia National Laboratories fiscal year 2002.

Energy Technology Data Exchange (ETDEWEB)

Palmer, David L.

2003-05-01

This report summarizes the purchasing and transportation activities of the Procurement and Logistics Management Center for Fiscal Year 2002. Activities for both the New Mexico and California locations are included.

Purchasing and Materials Management Organization, Sandia National Laboratories annual report, fiscal year 1993

Energy Technology Data Exchange (ETDEWEB)

Martin, D.R.

1994-02-01

This report summarizes the purchasing and transportation activities of the Purchasing and Materials Management Organization for Fiscal Year 1993. Activities for both the New Mexico and California locations are included.

Activation of hypothalamic RIP-Cre neurons promotes beiging of WAT via sympathetic nervous system.

Science.gov (United States)

Wang, Baile; Li, Ang; Li, Xiaomu; Ho, Philip Wl; Wu, Donghai; Wang, Xiaoqi; Liu, Zhuohao; Wu, Kelvin Kl; Yau, Sonata Sy; Xu, Aimin; Cheng, Kenneth Ky

2018-04-01

Activation of brown adipose tissue (BAT) and beige fat by cold increases energy expenditure. Although their activation is known to be differentially regulated in part by hypothalamus, the underlying neural pathways and populations remain poorly characterized. Here, we show that activation of rat-insulin-promoter-Cre (RIP-Cre) neurons in ventromedial hypothalamus (VMH) preferentially promotes recruitment of beige fat via a selective control of sympathetic nervous system (SNS) outflow to subcutaneous white adipose tissue (sWAT), but has no effect on BAT Genetic ablation of APPL2 in RIP-Cre neurons diminishes beiging in sWAT without affecting BAT, leading to cold intolerance and obesity in mice. Such defects are reversed by activation of RIP-Cre neurons, inactivation of VMH AMPK, or treatment with a β3-adrenergic receptor agonist. Hypothalamic APPL2 enhances neuronal activation in VMH RIP-Cre neurons and raphe pallidus, thereby eliciting SNS outflow to sWAT and subsequent beiging. These data suggest that beige fat can be selectively activated by VMH RIP-Cre neurons, in which the APPL2-AMPK signaling axis is crucial for this defending mechanism to cold and obesity. © 2018 The Authors.

Single-Shell Tank (SST) Retrieval Sequence Fiscal Year 2000 Update

International Nuclear Information System (INIS)

GARFIELD, J.S.

2000-01-01

This document describes the baseline single-shell tank (SST) waste retrieval sequence for the River Protection Project (RPP) updated for Fiscal Year 2000. The SST retrieval sequence identifies the proposed retrieval order (sequence), the tank selection and prioritization rationale, and planned retrieval dates for Hanford SSTs. In addition, the tank selection criteria and reference retrieval method for this sequence are discussed

FINANCIAL AUDIT: Capitol Preservation Fund's Fiscal Years 2001 and 2000 Financial Statements

National Research Council Canada - National Science Library

Franzel, Jeanette

2002-01-01

The statements of the financial position of the Capitol Preservation Fund (the Fund) as of September 30, 2001, and 2000 were audited, and the related statements of activities and statements of cash flows for the fiscal years then ended...

Atomic Safety and Licensing Board Panel annual report, fiscal year 1989

International Nuclear Information System (INIS)

Cotter, B.P. Jr.

1990-07-01

In Fiscal Year 1989, the Atomic Safety and Licensing Board Panel (ASLBP) handled 40 proceedings involving the construction, operation and maintenance of commercial nuclear power reactors or other activities requiring a license from the Nuclear Regulatory Commission. This report summarizes, highlights and analyzes how the wide-ranging issues raised in these proceedings were addressed by the Judges and Licensing Boards of the ASLBP during the year. 5 figs., 3 tabs

76 FR 5567 - Service Contract Inventory for Fiscal Year (FY) 2010

Science.gov (United States)

2011-02-01

... DEPARTMENT OF EDUCATION Service Contract Inventory for Fiscal Year (FY) 2010 AGENCY: Office of the Chief Financial Officer, U.S. Department of Education. ACTION: Notice of availability--FY 2010 Service.... Skelly, Chief Financial Officer. [FR Doc. 2011-2236 Filed 1-28-11; 11:15 am] BILLING CODE 4000-01-P ...

78 FR 10611 - Service Contract Inventory for Fiscal Year (FY) 2012

Science.gov (United States)

2013-02-14

... DEPARTMENT OF EDUCATION Service Contract Inventory for Fiscal Year (FY) 2012 AGENCY: Office of the Chief Financial Officer, U.S. Department of Education. ACTION: Notice of availability--FY 2012 service... Deputy Chief Financial Officer. [FR Doc. 2013-03441 Filed 2-13-13; 8:45 am] BILLING CODE 4000-01-P ...

2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. South Carolina State University. Sector: Four-Year Colleges and Universities

Science.gov (United States)

South Carolina Commission on Higher Education, 2005

2005-01-01

This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

Report of radioactivity investigation and research in fiscal year 1984

International Nuclear Information System (INIS)

1985-11-01

National Institute of Radiological Sciences has continuously carried out the investigation and research on the environmental radioactivity level due to the radioactive fallout accompanying nuclear explosion experiments and the radioactive substances released from nuclear facilities and on the safety analysis of those since fiscal year 1959 as a part of the radioactivity investigation and research of Science and Technology Agency. The importance of radioactivity investigation and research increases more accompanying the remarkable progress of the peaceful use of atomic energy and the emphasis placed on the safety analysis of atomic energy utilization. In such situation, in fiscal year 1984, by appropriating the total budget of about 105 million yen, the investigation of the radioactivity level and dose in environment, foods and human bodies, the investigation of the level around nuclear facilities, the business of radioactivity data center, the basic research on the evaluation of the results of radioactivity investigation, the training of environmental radiation monitoring technicians, and the investigation and research on the measurement of and countermeasures to emergency radiation exposure were carried out. In this book, the results of these investigation and research are reported. (Kako, I.)

EPA Sustainable Materials Management Program Strategic Plan for Fiscal Years 2017 – 2022

Science.gov (United States)

Covers fiscal years 2017 through 2022, and represents the collective thinking of EPA staff and management across the country, as well as input from many stakeholders, including states, industry, and non-governmental organizations.

Bellman Ford algorithm - in Routing Information Protocol (RIP)

Science.gov (United States)

Krianto Sulaiman, Oris; Mahmud Siregar, Amir; Nasution, Khairuddin; Haramaini, Tasliyah

2018-04-01

In a large scale network need a routing that can handle a lot number of users, one of the solutions to cope with large scale network is by using a routing protocol, There are 2 types of routing protocol that is static and dynamic, Static routing is manually route input based on network admin, while dynamic routing is automatically route input formed based on existing network. Dynamic routing is efficient used to network extensively because of the input of route automatic formed, Routing Information Protocol (RIP) is one of dynamic routing that uses the bellman-ford algorithm where this algorithm will search for the best path that traversed the network by leveraging the value of each link, so with the bellman-ford algorithm owned by RIP can optimize existing networks.

Army Hearing Program Status Report Quarter 1 Fiscal Year 2017

Science.gov (United States)

2017-03-27

Occupational Health Objectives for Fiscal Year 2016, 21 October 2015. Memorandum, Office of the Surgeon General, subject: Public Health Management System ...Army’s Safety and Occupational Health objectives. U.S. Army Medical Command (MEDCOM) Chief of Staff Memorandum, dated 15 December 2016, mandates... Occupational and Environmental Health Readiness System – Hearing Conservation (DOEHRS-HC), and an average of 2 CIV and 3 MIL losses were recorded

Changes in nuclear receptor corepressor RIP140 do not influence mitochondrial content in the cortex.

Science.gov (United States)

Herbst, Eric A F; Bonen, Arend; Holloway, Graham P

2015-10-01

Changes in nuclear receptor interacting protein 140 (RIP140) influences mitochondrial content in skeletal muscle; however, the translation of these findings to the brain has not been investigated. The present study examined the impact of overexpressing and ablating RIP140 on mitochondrial content in muscle and the cortex through examining mRNA, mtDNA, and mitochondrial protein content. Our results show that changes in RIP140 expression significantly alters markers of mitochondrial content in skeletal muscle but not the brain.

Waste management fiscal year 1998 progress report

International Nuclear Information System (INIS)

1998-01-01

The Waste Management Program is pleased to issue the Fiscal Year 1998 Progress Report presenting program highlights and major accomplishments of the last year. This year-end update describes the current initiatives in waste management and the progress DOE has made toward their goals and objectives, including the results of the waste management annual performance commitments. One of the most important program efforts continues to be opening the Waste Isolation Pilot Plant (WIPP), located near Carlsbad, New Mexico, for the deep geologic disposal of transuranic waste. A major success was achieved this year by the West Valley Demonstration Project in New York, which in June completed the project's production phase of high-level waste processing ahead of schedule and under budget. Another significant accomplishment this year was the award of two privatization contracts for major waste management operations, one at Oak ridge for transuranic waste treatment, and one at Hanford for the Tank Waste Remediation System privatization project. DOE is proud of the progress that has been made, and will continue to pursue program activities that allow it to safely and expeditiously dispose of radioactive and hazardous wastes across the complex, while reducing worker, public, and environmental risks

Atomic Safety and Licensing Board Panel annual report, Fiscal year 1992

International Nuclear Information System (INIS)

1993-09-01

In Fiscal Year 1992, the Atomic Safety and Licensing Board Panel (''the Panel'') handled 38 proceedings. The cases addressed issues in the construction, operation, and maintenance of commercial nuclear power reactors and other activities requiring a license from the Nuclear Regulatory Commission. This reports sets out the Panel's caseload during the year and summarizes, highlights, and analyzes how the wide-ranging issues raised in those proceedings were addressed by the Panel's judges and licensing boards

Repository Integration Program: RIP performance assessment and strategy evaluation model theory manual and user`s guide

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-11-01

This report describes the theory and capabilities of RIP (Repository Integration Program). RIP is a powerful and flexible computational tool for carrying out probabilistic integrated total system performance assessments for geologic repositories. The primary purpose of RIP is to provide a management tool for guiding system design and site characterization. In addition, the performance assessment model (and the process of eliciting model input) can act as a mechanism for integrating the large amount of available information into a meaningful whole (in a sense, allowing one to keep the ``big picture`` and the ultimate aims of the project clearly in focus). Such an integration is useful both for project managers and project scientists. RIP is based on a `` top down`` approach to performance assessment that concentrates on the integration of the entire system, and utilizes relatively high-level descriptive models and parameters. The key point in the application of such a ``top down`` approach is that the simplified models and associated high-level parameters must incorporate an accurate representation of their uncertainty. RIP is designed in a very flexible manner such that details can be readily added to various components of the model without modifying the computer code. Uncertainty is also handled in a very flexible manner, and both parameter and model (process) uncertainty can be explicitly considered. Uncertainty is propagated through the integrated PA model using an enhanced Monte Carlo method. RIP must rely heavily on subjective assessment (expert opinion) for much of its input. The process of eliciting the high-level input parameters required for RIP is critical to its successful application. As a result, in order for any project to successfully apply a tool such as RIP, an enormous amount of communication and cooperation must exist between the data collectors, the process modelers, and the performance. assessment modelers.

Research plan on geosphere stability for long-term isolation of radioactive waste. Scientific programme for fiscal years 2011

International Nuclear Information System (INIS)

Yasue, Ken-ichi; Asamori, Koichi; Kusano, Tomohiro; Saito-Kokubu, Yoko; Tanikawa, Shin-ichi; Niwa, Masakazu; Hanamuro, Takahiro; Yamasaki, Seiko; Yamada, Kunimi; Ishimaru, Tsuneari; Umeda, Koji

2011-07-01

The concept of geological disposal of HLW in Japan is based on a multi-barrier system which combines a stable geological environment with a robust barrier system. Potential geological host formations and their surroundings are chosen, in particular, for their long-term stability, taking into account the fact that Japan is located in a tectonically active zone. This report is a plan of research and development (R and D) on geosphere stability for long-term isolation of HLW in JAEA, in fiscal year 2011. The objectives and contents in fiscal year 2011 are described in detail based on the outline of 5 years plan (fiscal years 2010-2014). In addition, the planed framework is structured into the following categories: (1) Development and systematization of investigation techniques, (2) Development of models for long-term estimation and effective assessment, (3) Development of dating techniques. (author)

Research plan on geosphere stability for long-term isolation of radioactive waste. Scientific programme for fiscal years 2012

International Nuclear Information System (INIS)

Asamori, Koichi; Niwa, Masakazu; Hanamuro, Takahiro; Yamada, Kunimi; Kusano, Tomohiro; Makuuchi, Ayumu; Takatori, Ryoichi; Saito-Kokubu, Yoko; Ishimaru, Tsuneari; Umeda, Koji

2012-07-01

The concept of geological disposal of HLW in Japan is based on a multi-barrier system which combines a stable geological environment with a robust barrier system. Potential geological host formations and their surroundings are chosen, in particular, for their long-term stability, taking into account the fact that Japan is located in a tectonically active zone. This report is a plan of research and development (R and D) on geosphere stability for long-term isolation of HLW in JAEA, in fiscal year 2012. The objectives and contents in fiscal year 2012 are described in detail based on the outline of 5 years plan (fiscal years 2010-2014). In addition, the planned framework is structured into the following categories: (1) Development and systematization of investigation techniques, (2) Development of models for long-term estimation and effective assessment, (3) Development of dating techniques. (author)

Research plan on geosphere stability for long-term isolation of radioactive waste. Scientific programme for fiscal years 2010

International Nuclear Information System (INIS)

Yasue, Ken-ichi; Asamori, Koichi; Yamada, Kunimi; Saito-Kokubu, Yoko; Yamasaki, Seiko; Kurosawa, Hideki; Tanikawa, Shin-ichi; Negi, Tateyuki; Kusano, Tomohiro; Hanamuro, Takahiro; Ishimaru, Tsuneari; Umeda, Koji

2010-09-01

The concept of geological disposal of HLW in Japan is based on a multibarrier system which combines a stable geological environment with an engineered barrier system. Potential geological host formations and their surroundings are chosen, in particular, for their long-term stability, taking into account the fact that Japan is located in a tectonically active zone. This report is a plan of research and development (R and D) for geosphere stability for long-term isolation of HLW in JAEA, in fiscal year 2010. The objectives and contents in fiscal year 2010 are described in detail based on the outline of 5 years plan (fiscal years 2010-2014). In addition, the plan framework is structured into the following categories: (1) Development and systematization of investigation techniques, (2) Development of models for long-term estimation and effective assessment, (3) Development of dating techniques. (author)

Annual report: Purchasing and Materials Management Organization, Sandia National Laboratories, fiscal year 1992

Energy Technology Data Exchange (ETDEWEB)

Zaeh, R.A.

1993-04-01

This report summarizes the purchasing and transportation activities of the Purchasing and Materials Management Organization for Fiscal Year 1992. Activities for both the New Mexico and California locations are included. Topics covered in this report include highlights for fiscal year 1992, personnel, procurements (small business procurements, disadvantaged business procurements, woman-owned business procurements, New Mexico commercial business procurements, Bay area commercial business procurements), commitments by states and foreign countries, and transportation activities. Also listed are the twenty-five commercial contractors receiving the largest dollar commitments, commercial contractors receiving commitments of $1,000 or more, integrated contractor and federal agency commitments of $1,000 or more from Sandia National Laboratories/New Mexico and California, and transportation commitments of $1,000 or more from Sandia National Laboratories/New Mexico and California.

Energy Materials Coordinating Committee (EMaCC) annual technical report, fiscal year 1984 with fiscal year 1985 data

Energy Technology Data Exchange (ETDEWEB)

None

1985-07-01

The Department of Energy funded about 374 million dollars of materials science and technology activities in both fiscal years 1984 and 1985. These funds and the commensurate program management responsibilities resided in 21 DOE program offices, each of which has its own mission and responsibilities. The Energy Materials Coordinating Committee (EMaCC) provides a formal mechanism to insure coordinated planning and maximum programmatic effectiveness for the Department's 374 million dollar per year materials effort. The EMaCC reports to the Director of the Office of Energy Research who in turn has oversight responsibilities for proper coordination of the technical programs of the Department. In carrying out this responsibility, EMaCC hosts meetings, organizes working groups, and publishes an annual technical report. This report is mandated by the EMaCC Terms of Reference. Its purpose is to disseminate information on the DOE materials programs for more effective coordination. It describes the materials research programs of various offices and divisions within the Department for FY 1984, contains funding information for FYs 1984 and 1985, and summarizes EMaCC activities for FY 1985.

Energy Materials Coordinating Committee (EMaCC) annual technical report, fiscal year 1984 with fiscal year 1985 data

International Nuclear Information System (INIS)

1985-07-01

The Department of Energy funded about 374 million dollars of materials science and technology activities in both fiscal years 1984 and 1985. These funds and the commensurate program management responsibilities resided in 21 DOE program offices, each of which has its own mission and responsibilities. The Energy Materials Coordinating Committee (EMaCC) provides a formal mechanism to insure coordinated planning and maximum programmatic effectiveness for the Department's 374 million dollar per year materials effort. The EMaCC reports to the Director of the Office of Energy Research who in turn has oversight responsibilities for proper coordination of the technical programs of the Department. In carrying out this responsibility, EMaCC hosts meetings, organizes working groups, and publishes an annual technical report. This report is mandated by the EMaCC Terms of Reference. Its purpose is to disseminate information on the DOE materials programs for more effective coordination. It describes the materials research programs of various offices and divisions within the Department for FY 1984, contains funding information for FYs 1984 and 1985, and summarizes EMaCC activities for FY 1985

Contract 98, Appendix F self-assessment report for Fiscal Year 2003

Energy Technology Data Exchange (ETDEWEB)

Albert (Editor), Rich

2003-10-15

This report summarizes the Ernest Orlando Lawrence Berkeley National Laboratory internal assessment of Laboratory operational and administrative performance in key support functions for Fiscal Year (FY) 2003. The report provides documentation of ongoing performance-based management and oversight processes required by the Department of Energy (DOE) to monitor, measure, and evaluate Berkeley Lab work.

Basalt Waste Isolation Project. Annual report, fiscal year 1980

International Nuclear Information System (INIS)

1980-11-01

During this fiscal year the information available in the fields of geology and hydrology of the Columbia Plateau was consolidated and two reports were issued summarizing this information. In addition, the information on engineered barriers was consolidated and a report summarizing the research to date on waste package development and design of borehole seals was prepared. The waste package studies, when combined with the hydrologic integration, revealed that even under extreme disruptive conditions, a repository in basalt with appropriately designed waste packages can serve as an excellent barrier for containment of radionuclides for the long periods of time required for waste isolation. On July 1, 1980, the first two heater tests at the Near-Surface Test Facility were started and have been successfully operated to this date. The papers on the Near-Surface Test Facility section of this report present the results of the equipment installed and the preliminary results of the testing. In October 1979, the US Department of Energy selected the joint venture of Kaiser Engineers/Parsons Brinckerhoff Quade and Douglas, Inc., to be the architect-engineer to produce a conceptual design of a repository in basalt. During the year, this design has progressed and concept selection has now been completed. This annual report presents a summary of the highlights of the work completed during fiscal year 1980. It is intended to supplement and summarize the nearly 200 papers and reports that have been distributed to date as a part of the Basalt Waste Isolation Project studies

Excavation of shafts and research galleries at the Mizunami Underground Research Laboratory (MIU). Construction progress report, fiscal year 2006

International Nuclear Information System (INIS)

2012-12-01

This progress report presents an outline compilation of construction activities, primary tasks performed, construction progress and problems reported in Fiscal Year 2006. The outline of construction activities is a summary based on the scope of work planned in 2006. The main activities are based on the Tono Geoscience Center weekly reports. The construction progress is based on the planned and actual schedules and the Tono Geoscience Center weekly reports. The problems reported are based on accident reports, natural disasters, nonconformance and defects recorded by the safety manager of the Geoscience Facility Construction Section. Construction plan of the MIU construction project No.2 (started on July 1, 2006) is described in this report. Regarding the plan and actual performance of MIU construction project No.1 (completed on June 30, 2006), it is described in “Construction Progress Report from Fiscal Year 2002 to Fiscal Year 2005(including a part of Fiscal Year 2006)”. The following appendices are attached: construction plan, risk assessment reports, the photos of construction activities and technical specifications of the construction project No.2. (author)

Status of GAO Recommendations to the Department of Defense (Fiscal Years 2001-2007)

National Research Council Canada - National Science Library

Pickup, Sharon L

2008-01-01

Section 402 of the Concurrent Resolution on the Budget for Fiscal Year 2009 required us to report to the appropriate congressional committees by the end of the 110th Congress regarding the Department of Defense's (DOD...

Fiscal Year 2006 Salary Report for the Illinois Public Community Colleges

Science.gov (United States)

Illinois Community College Board, 2006

2006-01-01

Data about compensation received by employees in Illinois' 48 Illinois public community colleges are gathered by the Illinois Community College Board (ICCB). Data in the Fiscal Year 2006 Salary Report reflect the census date of October 1, 2005. Data are presented by peer groups with statewide totals. Most of the 25 tables in this report contain…

42 CFR 412.208 - Puerto Rico rates for Federal fiscal year 1988.

Science.gov (United States)

2010-10-01

... by— (1) Adjusting for variations in case mix among hospitals; (2) Excluding an estimate of indirect... rates for Federal fiscal year 1988. (a) General rule. CMS determines the Puerto Rico adjusted DRG...) Geographic classification. (1) For purposes of this paragraph (e) of this section, the following definitions...

2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. University of South Carolina Upstate. Sector: Four-Year Colleges and Universities

Science.gov (United States)

South Carolina Commission on Higher Education, 2005

2005-01-01

This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. University of South Carolina Aiken. Sector: Four-Year Colleges and Universities

Science.gov (United States)

South Carolina Commission on Higher Education, 2005

2005-01-01

This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. University of South Carolina Beaufort. Sector: Four-Year Colleges and Universities

Science.gov (United States)

South Carolina Commission on Higher Education, 2005

2005-01-01

This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

Ecological Monitoring and Compliance Program Fiscal Year 1999 Report

Energy Technology Data Exchange (ETDEWEB)

Cathy A. Wills

1999-12-01

The Ecological and Compliance program, funded through the U. S. Department of Energy, Nevada Operations Office, monitors the ecosystem of the Nevada Test Site (NTS) and ensures compliance with laws and regulations pertaining to NTS biota. This report summarizes the program's activities conducted by Bechtel Nevada during fiscal year 1999. Program activities included: (1) biological surveys at proposed construction sites (2) desert tortoise compliance (3) ecosystem mapping (4) sensitive species and unique habitat monitoring and (5) biological monitoring at the HAZMAT Spill Center.

Annual report of Nuclear Engineering Research Laboratory, Faculty of Engineering, University of Tokyo, fiscal year 1996

International Nuclear Information System (INIS)

1997-08-01

This report summarizes research and educational activities, operation status of the research facilities of the Nuclear Engineering Research Laboratory, Faculty of Engineering, University of Tokyo on fiscal year 1996. This facility has four major research facilities such as fast neutron source reactor 'Yayoi', electron Linac, fundamental experiment facility for nuclear fusion reactor blanket design and high fluence irradiation facility(HIT). Education and research activities are conducted in a wide fields of nuclear engineering using these facilities. The former two facilities are available for various studies by universities all over Japan, facility for nuclear fusion reactor blanket design is utilized for research within the Faculty of Engineering and HIT is used for the research within the University of Tokyo. The facility established a plan to reorganized into a nation wide research collaboration center in fiscal year 1995 and after further discussion of a future program it is decided to hold 'Nuclear energy symposium' periodically after fiscal year 1997 as a part of the activity for appealing the research results to the public. (G.K.)

76 FR 8811 - FTA Fiscal Year 2011 Apportionments, Allocations and Program Information: Corrections

Science.gov (United States)

2011-02-15

... DEPARTMENT OF TRANSPORTATION Federal Transit Administration FTA Fiscal Year 2011 Apportionments, Allocations and Program Information: Corrections AGENCY: Federal Transit Administration (FTA), DOT. ACTION...) that were published in the February 8, 2011, (76 FR 6958) Federal Transit Administration (FTA) notice...

Budget estimates: Fiscal year 1994. Volume 2: Construction of facilities

Science.gov (United States)

1994-01-01

The Construction of Facilities (CoF) appropriation provides contractual services for the repair, rehabilitation, and modification of existing facilities; the construction of new facilities and the acquisition of related collateral equipment; the acquisition or condemnation of real property; environmental compliance and restoration activities; the design of facilities projects; and advanced planning related to future facilities needs. Fiscal year 1994 budget estimates are broken down according to facility location of project and by purpose.

Volpe Center Office of Research and Technology Applications (ORTA) : fiscal year 2014 annual report

Science.gov (United States)

2014-12-01

Technology transfer activities performed by the Volpe National Transportation Systems Center during fiscal year 2014 in fulfillment of statutory Office of Research and Technology Applications (ORTA) responsibilities are summarized in this report.

Bibliography and documents issued list through fiscal year 1982

International Nuclear Information System (INIS)

1982-12-01

This document is a bibliography of the published reports, papers, and documents of the Basalt Waste Isolation Project (BWIP) that have been publicly released during fiscal years 1978 to 1982. A brief history of the National Waste Terminal Storage Program and the BWIP is included to provide the reader with the scope of activities involved in the technical endeavor to identify a potential geologic repository site for the permanent isolation of radioactive wastes. The bibliography is organized by scientific discipline and in chronological order. An author index is provided after the bibliography

Planning integration FY 1995 Multi-Year Program Plan (MYPP)/Fiscal Year Work Plan (FYWP)

International Nuclear Information System (INIS)

1994-09-01

This Multi-Year Program Plan (MYPP) for the Planning Integration Program, Work Breakdown structure (WBS) Element 1.8.2, is the primary management tool to document the technical, schedule, and cost baseline for work directed by the US Department of Energy (DOE), Richland Operations Office (RL). As an approved document, it establishes a binding agreement between RL and the performing contractors for the work to be performed. It was prepared by the Westinghouse Hanford Company (WHC) and the Pacific Northwest Laboratory (PNL). This MYPP provides a picture from fiscal year 1995 through FY 2001 for the Planning Integration Program. The MYPP provides a window of detailed information for the first three years. It also provides 'execution year' work plans. The MYPP provides summary information for the next four years, documenting the same period as the Activity Data Sheets

Planning integration FY 1995 Multi-Year Program Plan (MYPP)/Fiscal Year Work Plan (FYWP)

Energy Technology Data Exchange (ETDEWEB)

1994-09-01

This Multi-Year Program Plan (MYPP) for the Planning Integration Program, Work Breakdown structure (WBS) Element 1.8.2, is the primary management tool to document the technical, schedule, and cost baseline for work directed by the US Department of Energy (DOE), Richland Operations Office (RL). As an approved document, it establishes a binding agreement between RL and the performing contractors for the work to be performed. It was prepared by the Westinghouse Hanford Company (WHC) and the Pacific Northwest Laboratory (PNL). This MYPP provides a picture from fiscal year 1995 through FY 2001 for the Planning Integration Program. The MYPP provides a window of detailed information for the first three years. It also provides `execution year` work plans. The MYPP provides summary information for the next four years, documenting the same period as the Activity Data Sheets.

Science to support DOE site cleanup: The Pacific Northwest National Laboratory Environmental Management Science Program awards. Fiscal year 1998 mid-year progress report

International Nuclear Information System (INIS)

1998-05-01

Pacific Northwest National Laboratory was awarded ten (10) Environmental Management Science Program (EMSP) research grants in Fiscal Year 1996 and six (6) in Fiscal Year 1997. This section summarizes how each grant addresses significant US Department of Energy (DOE) cleanup issues, including those at the Hanford Site. The technical progress made to date in each of these research projects is addressed in more detail in the individual progress reports contained in this document. This research is focused primarily in four areas: Tank Waste Remediation, Spent Nuclear Fuel and Nuclear Materials, Soil and Groundwater Cleanup, and Health Effects

Science to support DOE site cleanup: The Pacific Northwest National Laboratory Environmental Management Science Program awards. Fiscal year 1998 mid-year progress report

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-05-01

Pacific Northwest National Laboratory was awarded ten (10) Environmental Management Science Program (EMSP) research grants in Fiscal Year 1996 and six (6) in Fiscal Year 1997. This section summarizes how each grant addresses significant US Department of Energy (DOE) cleanup issues, including those at the Hanford Site. The technical progress made to date in each of these research projects is addressed in more detail in the individual progress reports contained in this document. This research is focused primarily in four areas: Tank Waste Remediation, Spent Nuclear Fuel and Nuclear Materials, Soil and Groundwater Cleanup, and Health Effects.

Report of fact-finding survey for atomic energy industry, fiscal year 1994

International Nuclear Information System (INIS)

1996-01-01

In fiscal year 1994, the economy in Japan progressed in the state of gradual restoration of business condition, and the real economical growth rate turned to 0.5% plus. The total supply of primary energy increased by 5.4% as compared with the last year. Nuclear power took 11.3% of total energy supply, which is the highest so far. The share of nuclear power generation in total generated electric power became 31.3%. The nuclear power stations that started operation were two plants, and as of the end of the fiscal year, 48 nuclear power plants with the installed capacity of 40.37 million kW were in operation. Five plants of 4997 MW were under construction. The long term plan on the research, development and utilization of atomic energy was shown as the plan up to 2010. The outlay related to nuclear power of electric power business increased by 7% as compared with the last year, but the sales related to atomic energy of mining and manufacturing industries decreased by 12%. The market of nuclear reactor materials becomes smaller, and maintenance, service and fuel cycle fields show growth, in this way, the structural change is advancing. The results of survey are reported. (K.I.)

2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. Medical University of South Carolina. Sector: Research Institutions

Science.gov (United States)

South Carolina Commission on Higher Education, 2005

2005-01-01

This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

2004-05 Performance Year Ratings Impacting Fiscal Year 2005-06. University of South Carolina Columbia. Sector: Research Institutions

Science.gov (United States)

South Carolina Commission on Higher Education, 2005

2005-01-01

This series of documents contains performance scoring information for 2004-2005 for individual institutions of higher education in South Carolina. This information is used in establishing 2005-2006 fiscal year allocations. Data includes: (1) Degrees Awarded; (2) Enrollment; (3) Average SAT score; (4) Faculty; (5) Tuition; and (6) Financial…

Quarterly fiscal policy

NARCIS (Netherlands)

Kendrick, D.A.; Amman, H.M.

2014-01-01

Monetary policy is altered once a month. Fiscal policy is altered once a year. As a potential improvement this article examines the use of feedback control rules for fiscal policy that is altered quarterly. Following the work of Blinder and Orszag, modifications are discussed in Congressional

Prolactin receptors in Rip-cre cells, but not in AgRP neurones, are involved in energy homeostasis.

Science.gov (United States)

Ladyman, S R; MacLeod, M A; Khant Aung, Z; Knowles, P; Phillipps, H R; Brown, R S E; Grattan, D R

2017-10-01

Among its many functions, prolactin has been implicated in energy homeostasis, particularly during pregnancy and lactation. The arcuate nucleus is a key site in the regulation of energy balance. The present study aimed to examine whether arcuate nucleus neuronal populations involved in energy homeostasis are prolactin responsive and whether they can mediate the effects of prolactin on energy homeostasis. To determine whether Agrp neurones or Rip-Cre neurones are prolactin responsive, transgenic mice expressing the reporter td-tomato in Agrp neurones (td-tomato/Agrp-Cre) or Rip-Cre neurones (td-tomato/Rip-Cre) were treated with prolactin and perfused 45 minutes later. Brains were processed for double-labelled immunohistochemistry for pSTAT5, a marker of prolactin-induced intracellular signalling, and td-tomato. In addition, Agrp-Cre mice and Rip-Cre mice were crossed with mice in which the prolactin receptor gene (Prlr) was flanked with LoxP sites (Prlr lox/lox mice). The Prlr lox/lox construct was designed such that Cre-mediated recombination resulted in deletion of the Prlr and expression of green fluorescent protein (GFP) in its place. In td-tomato/Rip-Cre mice, prolactin-induced pSTAT5 was co-localised with td-tomato, indicating that there is a subpopulation of Rip-Cre neurones in the arcuate nucleus that respond to prolactin. Furthermore, mice with a specific deletion of Prlr in Rip-Cre neurones had lower body weights, increased oxygen consumption, increased running wheel activity and numerous cells in the arcuate nucleus had positive GFP staining indicating deletion of Prlr from Rip-Cre neurones. By contrast, no co-localisation of td-tomato and pSTAT5 was observed in td-tomato/Agrp-Cre mice after prolactin treatment. Moreover, Prlr lox/lox /Agrp-Cre mice had no positive GFP staining in the arcuate nucleus and did not differ in body weight compared to littermate controls. Overall, these results indicate that Rip-Cre neurones in the arcuate nucleus are

77 FR 15142 - Updated Nuclear Regulatory Commission Fiscal Years 2008-2013 Strategic Plan

Science.gov (United States)

2012-03-14

... 2008-2013 Strategic Plan AGENCY: Nuclear Regulatory Commission. ACTION: Strategic plan. SUMMARY: The U...-1614, Volume 5, ``U.S. Nuclear Regulatory Commission, Fiscal Years [FY] 2008-2013 Strategic Plan,'' dated February 2012. The updated FY 2008-2013 strategic plan describes the agency's mission and...

76 FR 45826 - Medical Device User Fee Rates for Fiscal Year 2012

Science.gov (United States)

2011-08-01

... paper check: All paper checks must be in U.S. currency from a U.S. bank and made payable to the Food and... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0542] Medical Device User Fee Rates for Fiscal Year 2012 AGENCY: Food and Drug Administration, HHS. ACTION...

76 FR 26731 - Medicare Program; Hospice Wage Index for Fiscal Year 2012

Science.gov (United States)

2011-05-09

... care under Part A. See Tax Equity and Fiscal Responsibility Act of 1982 (TEFRA), Public Law 97-248, Sec... future cap years. See, e.g., Los Angeles Haven Hospice, Inc. v. Leavitt, 2009 WL 5868513 (C.D. Cal. 2009... the recalculation. The impact of this methodology will be that the fractional allocations for some...

Hanford Cultural Resources Laboratory annual report for Fiscal Year 1991

Energy Technology Data Exchange (ETDEWEB)

Chatters, J.C.; Gard, H.A.

1992-08-01

The Hanford Cultural Resources Laboratory (HCRL) was established by the US Department of Energy, Richland Field Office (RL) in 1987 as part of Pacific Northwest Laboratory. The HCRL provides support for managing the archaeological, historical, and cultural resources of the Hanford Site, Washington, in a manner consistent with the National Historic Preservation Act of 1966 (NHPA), the Archaeological Resources Protection Act of 1979 and the American Indian Religious Freedom Act of 1978. HCRL responsibilities have been set forth in the Hanford Cultural Resources Management Plan (HCRMP) as a prioritized list of tasks to be undertaken to keep the RL in compliance with federal statutes, regulations and guidelines. For fiscal year 1991 these tasks were to (1) ensure compliance with NHPA Section 106, (2) monitor the condition of known archaeological sites, (3) evaluate cultural resources for potential nomination to the National Register of Historic Places, (4) educate the public about cultural resources, (5) conduct a sample archaeological survey of Hanford lands, and (6) gather ethnohistorical data from Indian elders. Research conducted as a spinoff from these tasks is also reported. The archaeological site monitoring program is designed to determine whether the RL`s cultural resource management and protection policies are effective; results are used in planning for cultural resource site management and protection. Forty-one sites were monitored during this fiscal year.

Hanford Cultural Resources Laboratory annual report for Fiscal Year 1991

Energy Technology Data Exchange (ETDEWEB)

Chatters, J.C.; Gard, H.A.

1992-08-01

The Hanford Cultural Resources Laboratory (HCRL) was established by the US Department of Energy, Richland Field Office (RL) in 1987 as part of Pacific Northwest Laboratory. The HCRL provides support for managing the archaeological, historical, and cultural resources of the Hanford Site, Washington, in a manner consistent with the National Historic Preservation Act of 1966 (NHPA), the Archaeological Resources Protection Act of 1979 and the American Indian Religious Freedom Act of 1978. HCRL responsibilities have been set forth in the Hanford Cultural Resources Management Plan (HCRMP) as a prioritized list of tasks to be undertaken to keep the RL in compliance with federal statutes, regulations and guidelines. For fiscal year 1991 these tasks were to (1) ensure compliance with NHPA Section 106, (2) monitor the condition of known archaeological sites, (3) evaluate cultural resources for potential nomination to the National Register of Historic Places, (4) educate the public about cultural resources, (5) conduct a sample archaeological survey of Hanford lands, and (6) gather ethnohistorical data from Indian elders. Research conducted as a spinoff from these tasks is also reported. The archaeological site monitoring program is designed to determine whether the RL's cultural resource management and protection policies are effective; results are used in planning for cultural resource site management and protection. Forty-one sites were monitored during this fiscal year.

Fiscal year 1991 100 Areas CERCLA ecological investigations

International Nuclear Information System (INIS)

Sackschewsky, M.R.; Landeen, D.S.

1992-04-01

This report discusses the status of the ecological investigations conducted by Westinghouse Hanford Company during Fiscal Year 1991. These ecological investigations provide a basic description of the flora and fauna that inhabit the operable units, emphasizing species that have been given special status under existing state and/or federal laws. The 1991 Westinghouse Hanford Company field investigations have concentrated on the following: (1) bird surveys, (2) mammal and insect surveys, (3) vegetation surveys, and (4) vegetation sampling. Work being conducted as part of the vegetation surveys includes a biological assessment of threatened and endangered plants, which is being prepared as a separate document. Similar ecological investigations will be conducted at 100- N, K, and F operable units in 1992

The role of RIP3 mediated necroptosis in ouabain-induced spiral ganglion neurons injuries.

Science.gov (United States)

Wang, Xi; Wang, Ye; Ding, Zhong-jia; Yue, Bo; Zhang, Peng-zhi; Chen, Xiao-dong; Chen, Xin; Chen, Jun; Chen, Fu-quan; Chen, Yang; Wang, Ren-feng; Mi, Wen-juan; Lin, Ying; Wang, Jie; Qiu, Jian-hua

2014-08-22

Spiral ganglion neuron (SGN) injury is a generally accepted precursor of auditory neuropathy. Receptor-interacting protein 3 (RIP3) has been reported as an important necroptosis pathway mediator that can be blocked by necrostatin-1 (Nec-1). In our study, we sought to identify whether necroptosis participated in SGN injury. Ouabain was applied to establish an SGN injury model. We measured the auditory brain-stem response (ABR) threshold shift as an indicator of the auditory conditions. Positive β3-tubulin immunofluorescence staining indicated the surviving SGNs. RIP3 expression was evaluated using immunofluorescence, quantitative real-time polymerase chain reaction and western blot. SGN injury promoted an increase in RIP3 expression that could be suppressed by application of the necroptosis inhibitor Nec-1. A decreased ABR threshold shift and increased SGN density were observed when Nec-1 was administered with apoptosis inhibitor N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone (Z-VAD). These results demonstrated that necroptosis is an indispensable pathway separately from apoptosis leading to SGN death pathway, in which RIP3 plays an important role. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

76 FR 11554 - Fiscal Year 2010 Public Transportation on Indian Reservations Program Project Selections

Science.gov (United States)

2011-03-02

... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Fiscal Year 2010 Public Transportation... Interior for public transportation capital projects, operating costs and planning activities that are... authorized by the Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users...

Summary Report on the Audit of Defense Base Closure and Realignment Budget Data for Fiscal Year 1992 and 1993

Science.gov (United States)

1993-05-25

OFFICE OF THE INSPECTOR GENERAL SUMMARY REPORT ON THE AUDIT OF DEFENSE BASE CLOSURE AND REALIGNMENT BUDGET DATA FOR FISCAL YEARS 1992 AND 1993...ASSISTANT SECRETARY OF DEFENSE (INSTALLATIONS) SUBJECT: Summary Report on the Audit of Defense Base Closure and Realignment Budget Data for Fiscal Years...1992 and 1993 (Report No. 93-100) We are providing this final summary report for your information and use. The audit was required by Public Law

77 FR 547 - Fiscal Year 2011 Public Transportation on Indian Reservations Program Project Selections

Science.gov (United States)

2012-01-05

... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Fiscal Year 2011 Public Transportation... 5311 (c), Public Transportation on Indian Reservations program funds in support of the Tribal Transit... for public transportation services on and around Indian reservations. FOR FURTHER INFORMATION CONTACT...

Consolidated financial statements for fiscal year 1996

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-02-01

The following overview and accompanying audited financial statements have been prepared for Fiscal Year (FY) 1996 to report the financial position and the results of operations of the Department of Energy. These statements include the consolidated Statement of Financial Position and the consolidated Statement of Operations and Changes in Net Position. The statements have been prepared in accordance with the Office of Management and Budget Bulletin No. 94-01, Form and Content for Agency Financial Statements, and were developed in accordance with the hierarchy of accounting standards described therein. The overview provides a narrative on the Department of Energy`s mission, activities, and accomplishments. Utilizing performance measures as the primary vehicle for communicating Departmental accomplishments and results, this overview discusses the most significant measures while others are discussed in the supplemental information to the financial statements.

Learning Styles versus the Rip Van Winkle Syndrome.

Science.gov (United States)

Orsak, Lana

1990-01-01

Rip Van Winkle would not recognize Corsicana (Texas) High School since its curriculum coordinator began implementing learning styles techniques in various pilot programs. Lecturing to rows of bored students has been replaced by students' active involvement in group activities, listening centers, and tactile/kinesthetic exercises on the floor or at…

Fiscal Year 2015 U.S. Government Financial Statements: Need to Address the Governments Remaining Financial Management Challenges and Long Term Fiscal Path

Science.gov (United States)

2016-04-06

consolidated financial statements (governmentwide financial statements ). Unless these...the U.S. government’s fiscal year 2015 consolidated financial statements (governmentwide financial statements ), which is included in the Financial ...Processes Used to Prepare the U.S. Consolidated Financial Statements , GAO-15-630 (Washington, D.C.: July 30, 2015). A detailed discussion of

Ohio Department of Transportation State Infrastructure Bank Annual Financial Report : Federal Fiscal Year 2009

Science.gov (United States)

2009-01-01

The Ohio Department of Transportation is pleased to present the Federal : Fiscal Year (FFY) 2009 State Infrastructure Bank (SIB) Annual Financial : Report. : The portfolio of the FFY 2009 SIB had a total of nine loans totaling $9.0 : million and one ...

RIP1 regulates TNF-α-mediated lymphangiogenesis and lymphatic metastasis in gallbladder cancer by modulating the NF-κB-VEGF-C pathway.

Science.gov (United States)

Li, Cheng-Zong; Jiang, Xiao-Jie; Lin, Bin; Hong, Hai-Jie; Zhu, Si-Yuan; Jiang, Lei; Wang, Xiao-Qian; Tang, Nan-Hong; She, Fei-Fei; Chen, Yan-Ling

2018-01-01

Tumor necrosis factor alpha (TNF-α) enhances lymphangiogenesis in gallbladder carcinoma (GBC) via activation of nuclear factor (NF-κB)-dependent vascular endothelial growth factor-C (VEGF-C). Receptor-interacting protein 1 (RIP1) is a multifunctional protein in the TNF-α signaling pathway and is highly expressed in GBC. However, whether RIP1 participates in the signaling pathway of TNF-α-mediated VEGF-C expression that enhances lymphangiogenesis in GBC remains unclear. The RIP1 protein levels in the GBC-SD and NOZ cells upon stimulation with increasing concentrations of TNF-α as indicated was examined using Western blot. Lentiviral RIP1 shRNA and siIκBα were constructed and transduced respectively them into NOZ and GBC-SD cells, and then PcDNA3.1-RIP1 vectors was transduced into siRIP1 cell lines to reverse RIP1 expression. The protein expression of RIP1, inhibitor of NF-κB alpha (IκBα), p-IκBα, TAK1, NF-κB essential modulator were examined through immunoblotting or immunoprecipitation. Moreover, VEGF-C mRNA levels were measured by quantitative real-time polymerase chain reaction, VEGF-C protein levels were measured by immunoblotting and enzyme-linked immunosorbent assay, and VEGF-C promoter and NF-κB activities were quantified using a dual luciferase reporter assay. The association of NF-κB with the VEGF-C promoter was analysed by chromatin immunoprecipitation assay. A three-dimensional coculture method and orthotopic transplantation nude mice model were used to evaluate lymphatic tube-forming and metastasis ability in GBC cells. The expression of RIP1 protein, TNF-α protein and lymphatic vessels in human GBC tissues was examined by immunohistochemistry, and the dependence between RIP1 protein with TNF-α protein and lymphatic vessel density was analysed. TNF-α dose- and time-dependently increased RIP1 protein expression in the GBC-SD and NOZ cells of GBC, and the strongest effect was observed with a concentration of 50 ng/ml. RIP1 is fundamental

Fiscal Year 1999 memorandum of understanding for the TWRS characterization project

International Nuclear Information System (INIS)

HUNT, J.W.

1998-01-01

During fiscal year 1999, the level of success achieved by the Tank Waste Remediation System (TWRS) shall be determined by specific performance measures. These measures take the form of significant deliverables, one of which is the completion of Tank Characterization Reports (TCRS). In order to achieve success regarding the TCR performance deliverable, multiple organizations across TWRS must work together. Therefore, the requirements and expectations needed from each of these TWRS organizations were examined in order to gain an understanding of the performance necessary from each organization to achieve the end deliverable. This memorandum of understanding (MOU) documents the results of this review and establishes the performance criteria by which TWRS will assess its progress and success. These criteria have been determined based upon a TWRS Characterization Project budget of $42.1 million for fiscal year 1999; if this budget is changed or the currently identified workscope is modified, this MOU will need to be revised accordingly. This MOU is subdivided into six sections, where sections three through six each identify individual interfaces between TWRS organizations. The specific performance criteria related to each TWRS organizational interface are then delineated in the section, along with any additional goals or issues pertaining to that interface

Fiscal year 1998 memorandum of understanding for the TWRS characterization project

International Nuclear Information System (INIS)

Schreiber, R.D.

1998-01-01

During fiscal year 1998, the level of success achieved by the Tank Waste Remediation System (TWRS) shall be determined by specific performance measures. These measures take the form of significant deliverables, one of which is the completion of Tank Characterization Reports (TCRs). In order to achieve success regarding the TCR performance deliverable, multiple organizations across TWRS must work together. Therefore, the requirements and expectations needed from each of these TWRS organizations were examined in order to gain an understanding of the performance necessary from each organization to achieve the end deliverable. This memorandum of understanding (MOU) documents the results of this review and establishes the performance criteria by which TWRS will assess its progress and success. These criteria have been determined based upon a TWRS Characterization Project budget of $47.5 million for fiscal year 1998; if this budget is changed or the currently identified work scope is modified, this MOU will need to be revised accordingly. This MOU is subdivided into six sections, where sections three through six each identify individual interfaces between TWRS organizations. The specific performance criteria related to each TWRS organizational interface are then delineated in the section, along with any additional goals or issues pertaining to that interface

Geotechnical support and topical studies for nuclear waste geologic repositories: Annual report, Fiscal Year 1986

International Nuclear Information System (INIS)

1986-11-01

The multidisciplinary project was initiated in fiscal year 1986. It comprises two major interrelated parts: (1) Technical Assistance. This part of the project includes: (a) review of the progress of major projects in the DOE Office of Civilian Radioactive Waste Management Program and advise the Engineering and Geotechnology Division on significant technical issues facing each project; (b) analyze geotechnical data, reports, tests, surveys and plans for the different projects; (c) review and comment on major technical reports and other program documents such as site characterization plans and area characterization plans and (d) provide scientific and technical input at technical meetings. (2) Topical Studies. This activity comprises studies on scientific and technical topics, and issues of significance to in-situ testing, test analysis methods, and performance assessment of nuclear waste geologic repositories. The subjects of study were selected based on discussions with DOE staff. For fiscal year 1986, one minor and one major area of investigation were undertaken. The minor topic is a preliminary consideration and planning exercise for post-closure monitoring studies. The major topic, with subtasks involving various geoscience disciplines, is on the mechanical, hydraulic, geophysical and geochemical properties of fractures in geologic rock masses. The present report lists the technical reviews and comments made during the fiscal year and summarizes the technical progress of the topical studies

RIP2 Is a Critical Regulator for NLRs Signaling and MHC Antigen Presentation but Not for MAPK and PI3K/Akt Pathways.

Science.gov (United States)

Wu, Xiao Man; Chen, Wen Qin; Hu, Yi Wei; Cao, Lu; Nie, Pin; Chang, Ming Xian

2018-01-01

RIP2 is an adaptor protein which is essential for the activation of NF-κB and NOD1- and NOD2-dependent signaling. Although NOD-RIP2 axis conservatively existed in the teleost, the function of RIP2 was only reported in zebrafish, goldfish, and rainbow trout in vitro . Very little is known about the role and mechanisms of piscine NOD-RIP2 axis in vivo . Our previous study showed the protective role of zebrafish NOD1 in larval survival through CD44a-mediated activation of PI3K-Akt signaling. In this study, we examined whether RIP2 was required for larval survival with or without pathogen infection, and determined the signaling pathways modulated by RIP2. Based on our previous report and the present study, our data demonstrated that NOD1-RIP2 axis was important for larval survival in the early ontogenesis. Similar to NOD1, RIP2 deficiency significantly affected immune system processes. The significantly enriched pathways were mainly involved in immune system, such as "Antigen processing and presentation" and "NOD-like receptor signaling pathway" and so on. Furthermore, both transcriptome analysis and qRT-PCR revealed that RIP2 was a critical regulator for expression of NLRs (NOD-like receptors) and those genes involved in MHC antigen presentation. Different from NOD1, the present study showed that NOD1, but not RIP2 deficiency significantly impaired protein levels of MAPK pathways. Although RIP2 deficiency also significantly impaired the expression of CD44a, the downstream signaling of CD44a-Lck-PI3K-Akt pathway remained unchanged. Collectively, our works highlight the similarity and discrepancy of NOD1 and RIP2 in the regulation of immune signaling pathways in the zebrafish early ontogenesis, and confirm the crucial role of RIP2 in NLRs signaling and MHC antigen presentation, but not for MAPK and PI3K/Akt pathways.

Hanford Site Environmental Restoration Program 1994 fiscal year work plan

International Nuclear Information System (INIS)

1993-01-01

Site Management System (SMS) guidance requires a Fiscal Year Work Plan (FYWP) to be prepared for the Environmental Restoration (ER) Mission Area and all related programs. This revision is a complete update to cover the FY 1994 time period. This document describes the overall ER Missions Area and provides FYWP appendices for each of the following five program areas: Remedial Action (RA); Decontamination and Decommissioning (D ampersand D); Project Management and Support (PM ampersand S); Surveillance and Maintenance (S ampersand M); and Disposal Facilities (DF)

Environmental Measurements Laboratory fiscal year 1998: Accomplishments and technical activities

Energy Technology Data Exchange (ETDEWEB)

Erickson, M.D.

1999-01-01

The Environmental Measurements Laboratory (EML) is government-owned, government-operated, and programmatically under the DOE Office of Environmental Management. The Laboratory is administered by the Chicago Operations Office. EML provides program management, technical assistance and data quality assurance for measurements of radiation and radioactivity relating to environmental restoration, global nuclear nonproliferation, and other priority issues for the Department of Energy, as well as for other government, national, and international organizations. This report presents the technical activities and accomplishments of EML for Fiscal Year 1998.

Annual report to Congress on Federal Government Energy Management and Conservation Programs, Fiscal Year 1998

Energy Technology Data Exchange (ETDEWEB)

None

2000-03-20

In fulfillment of statutory requirements, this report provides information on energy consumption in Federal buildings and operations and also documents activities conducted by Federal agencies in fulfilling those requirements during Fiscal Year 1998.

Annual report to Congress on Federal Government Energy Management and Conservation Programs, Fiscal Year 1997

Energy Technology Data Exchange (ETDEWEB)

None

1999-08-13

In fulfillment of statutory requirements, this report provides information on energy consumption in Federal buildings and operations and also documents activities conducted by Federal agencies in fulfilling those requirements during Fiscal Year 1997.

NOD1CARD Might Be Using Multiple Interfaces for RIP2-Mediated CARD-CARD Interaction: Insights from Molecular Dynamics Simulation.

Directory of Open Access Journals (Sweden)

Jitendra Maharana

Full Text Available The nucleotide-binding and oligomerization domain (NOD-containing protein 1 (NOD1 plays the pivotal role in host-pathogen interface of innate immunity and triggers immune signalling pathways for the maturation and release of pro-inflammatory cytokines. Upon the recognition of iE-DAP, NOD1 self-oligomerizes in an ATP-dependent fashion and interacts with adaptor molecule receptor-interacting protein 2 (RIP2 for the propagation of innate immune signalling and initiation of pro-inflammatory immune responses. This interaction (mediated by NOD1 and RIP2 helps in transmitting the downstream signals for the activation of NF-κB signalling pathway, and has been arbitrated by respective caspase-recruitment domains (CARDs. The so-called CARD-CARD interaction still remained contradictory due to inconsistent results. Henceforth, to understand the mode and the nature of the interaction, structural bioinformatics approaches were employed. MD simulation of modelled 1:1 heterodimeric complexes revealed that the type-Ia interface of NOD1CARD and the type-Ib interface of RIP2CARD might be the suitable interfaces for the said interaction. Moreover, we perceived three dynamically stable heterotrimeric complexes with an NOD1:RIP2 ratio of 1:2 (two numbers and 2:1. Out of which, in the first trimeric complex, a type-I NOD1-RIP2 heterodimer was found interacting with an RIP2CARD using their type-IIa and IIIa interfaces. However, in the second and third heterotrimer, we observed type-I homodimers of NOD1 and RIP2 CARDs were interacting individually with RIP2CARD and NOD1CARD (in type-II and type-III interface, respectively. Overall, this study provides structural and dynamic insights into the NOD1-RIP2 oligomer formation, which will be crucial in understanding the molecular basis of NOD1-mediated CARD-CARD interaction in higher and lower eukaryotes.

Technical Direction and Laboratories Fiscal Year 1999 Annual Report

International Nuclear Information System (INIS)

CRAWFORD, B.A.

2000-01-01

This annual report summarize achievements and list reports issued by members of TDandL, NHC group during Fiscal Year (FY) 1999, (October 1, 1998 through September 30, 1999). This report, issued by this organization, describes work in support of the Hanford Site and other U S . Department of Energy, Richland Operations Office (DOE-RL) programs. It includes information on the organization make-up, interfaces, and mission of the group. The TDandL is a group of highly qualified personnel with diverse disciplines (primarily chemistry specialties) that provide process, analytical, and in-situ chemistry services to engineering customers. This year of operation and interfaces with other contract organizations consumed considerable administrative efforts. Attention was directed to the technical challenges presented by the changing roles, responsibilities, and priorities of Hanford programs

Director's Discretionary Research and Development Program: Annual Report, Fiscal Year 2006

Energy Technology Data Exchange (ETDEWEB)

2007-03-01

The Director's Discretionary Research and Development Program, Annual Report Fiscal Year 2006 is an annual management report that summarizes research projects funded by the DDRD program. The NREL DDRD program comprises projects that strengthen NREL's four technical competencies: Integrated Systems, Renewable Electricity, Renewable Fuels, and Strategic Analysis.

Savannah River Site`s Site Specific Plan. Environmental restoration and waste management, fiscal year 1992

Energy Technology Data Exchange (ETDEWEB)

1991-08-01

This Site Specific Plan (SSP) has been prepared by the Savannah River Site (SRS) in order to show the Environmental Restoration and Waste Management activities that were identified during the preparation of the Department of Energy-Headquarters (DOE-HQ) Environmental Restoration and Waste Management Five-Year Plan (FYP) for FY 1992--1996. The SSP has been prepared in accordance with guidance received from DOE-HQ. DOE-SR is accountable to DOE-HQ for the implementation of this plan. The purpose of the SSP is to develop a baseline for policy, budget, and schedules for the DOE Environmental Restoration and Waste Management activities. The plan explains accomplishments since the Fiscal Year (FY) 1990 plan, demonstrates how present and future activities are prioritized, identifies currently funded activities and activities that are planned to be funded in the upcoming fiscal year, and describes future activities that SRS is considering.

The Hanford Site Environmental Restoration Program 1993 fiscal year work plan

International Nuclear Information System (INIS)

1992-09-01

Site Management System (SMS) guidance requires a Fiscal Year Work Plan (FYWP) be prepared for the Environmental Restoration (ER) Mission Area and all related programs. This document describes the overall ER Mission Area and provides FYWP appendixes for each of the five program areas: Remedial Action (RA); Decontamination and Decommissioning (D ampersand D); Project Management and Support (PM ampersand S); Surveillance and Maintenance (S ampersand M); and Treatment, Storage, and/or Disposal (TSD)

RapidRIP quantifies the intracellular metabolome of 7 industrial strains of E. coli

DEFF Research Database (Denmark)

McCloskey, Douglas; Xu, Julia; Schrübbers, Lars

2018-01-01

Fast metabolite quantification methods are required for high throughput screening of microbial strains obtained by combinatorial or evolutionary engineering approaches. In this study, a rapid RIP-LC-MS/MS (RapidRIP) method for high-throughput quantitative metabolomics was developed and validated...... to quantify the metabolome of seven industrial strains of E. coli revealing significant differences in glycolytic, pentose phosphate, TCA cycle, amino acid, and energy and cofactor metabolites were found. These differences translated to statistically and biologically significant differences in thermodynamics...

Calcination/dissolution chemistry development Fiscal year 1995

International Nuclear Information System (INIS)

Delegard, C.H.

1995-09-01

The task open-quotes IPC Liaison and Chemistry of Thermal Reconstitutionclose quotes is a $300,000 program that was conducted in Fiscal Year (FY) 1995 with U.S. Department of Energy (DOE) Office of Research and Development (EM-53) Efficient Separations and Processing Crosscutting Program supported under technical task plan (TTP) RL4-3-20-04. The principal investigator was Cal Delegard of the Westinghouse Hanford Company (WHC). The task encompassed the following two subtasks related to the chemistry of alkaline Hanford Site tank waste: (1) Technical Liaison with the Institute of Physical Chemistry of the Russian Academy of Science (IPC/RAS) and its research into the chemistry of transuranic elements (TRU) and technetium (Tc) in alkaline media. (2) Laboratory investigation of the chemistry of calcination/dissolution (C/D) (or thermal reconstitution) as an alternative to the present reference Hanford Site tank waste pretreatment flowsheet, Enhanced Sludge Washing (ESW). This report fulfills the milestone for the C/D subtask to open-quotes Provide End-of-Year Report on C/D Laboratory Test Resultsclose quotes due 30 September 1995. A companion report, fulfilling the milestone to provide an end-of-year report on the IPC/RAS liaison, also has been prepared

Ohio Department of Transportation State Infrastructure Bank Annual Financial Report : Federal Fiscal Year 2004

Science.gov (United States)

2004-01-01

The Ohio Department of Transportation is pleased to present the Federal Fiscal : Year 2004 State Infrastructure Bank (SIB) Annual Financial Report. The portfolio of : the FFY 04 SIB had a total of nineteen loans in the amount of $47,340,891. : A comp...

Ohio Department of Transportation State Infrastructure Bank Annual Financial Report : Federal Fiscal Year 2008

Science.gov (United States)

2008-01-01

The Ohio Department of Transportation is pleased to present the Federal Fiscal Year (FFY) 2008 State Infrastructure Bank (SIB) Annual Financial Report. The portfolio of the FFY 2008 SIB had a total of five loans totaling $22.1 million. Since the begi...

Ohio Department of Transportation State Infrastructure Bank Annual Financial Report : Federal Fiscal Year 2007

Science.gov (United States)

2007-01-01

The Ohio Department of Transportation is pleased to present the Federal : Fiscal Year (FFY) 2007 State Infrastructure Bank (SIB) Annual Financial : Report. : The portfolio of the FFY 2007 SIB had a total of 13 loans and 1 bond in the : amount of $17....

Computable general equilibrium model fiscal year 2013 capability development report

Energy Technology Data Exchange (ETDEWEB)

Edwards, Brian Keith [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Rivera, Michael Kelly [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Boero, Riccardo [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2016-05-17

This report documents progress made on continued developments of the National Infrastructure Simulation and Analysis Center (NISAC) Computable General Equilibrium Model (NCGEM), developed in fiscal year 2012. In fiscal year 2013, NISAC the treatment of the labor market and tests performed with the model to examine the properties of the solutions computed by the model. To examine these, developers conducted a series of 20 simulations for 20 U.S. States. Each of these simulations compared an economic baseline simulation with an alternative simulation that assumed a 20-percent reduction in overall factor productivity in the manufacturing industries of each State. Differences in the simulation results between the baseline and alternative simulations capture the economic impact of the reduction in factor productivity. While not every State is affected in precisely the same way, the reduction in manufacturing industry productivity negatively affects the manufacturing industries in each State to an extent proportional to the reduction in overall factor productivity. Moreover, overall economic activity decreases when manufacturing sector productivity is reduced. Developers ran two additional simulations: (1) a version of the model for the State of Michigan, with manufacturing divided into two sub-industries (automobile and other vehicle manufacturing as one sub-industry and the rest of manufacturing as the other subindustry); and (2) a version of the model for the United States, divided into 30 industries. NISAC conducted these simulations to illustrate the flexibility of industry definitions in NCGEM and to examine the simulation properties of in more detail.

Rotary Valve & Beamline Highlights for Fiscal Year 2017

Energy Technology Data Exchange (ETDEWEB)

Fitsos, P [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2017-09-21

This Fiscal Year (FY) work was divided between continued testing and characterization work of the Rotary Valve (RV) and mechanical engineering support for the beamline hardware stands. This configuration is more like the final setup with the accelerator firing deuterons down the evacuated beamline toward the RV for interaction with the deuterium and neutron production. The beamline cells were part of an experiment to reduce the impact that RV gas would have on the beamline vacuum. This work will be reported separately from this report. Previous testing had been with the beamline at atmospheric pressure and now the goal was to get test results of the RV with it connected to a beamline that’s running at some level of vacuum.

77 FR 15529 - Revision of Fee Schedules; Fee Recovery for Fiscal Year 2012

Science.gov (United States)

2012-03-15

... and 171 Revision of Fee Schedules; Fee Recovery for Fiscal Year 2012; Proposed Rule #0;#0;Federal... REGULATORY COMMISSION 10 CFR Parts 170 and 171 [NRC-2011-0207] RIN 3150-AJ03 Revision of Fee Schedules; Fee..., inspection, and annual fees charged to its applicants and licensees. The proposed amendments are necessary to...

76 FR 14747 - Revision of Fee Schedules; Fee Recovery for Fiscal Year 2011

Science.gov (United States)

2011-03-17

... 171 Revision of Fee Schedules; Fee Recovery for Fiscal Year 2011; Proposed Rule #0;#0;Federal Register... COMMISSION 10 CFR Parts 170 and 171 RIN 3150-AI93 [NRC-2011-0016] Revision of Fee Schedules; Fee Recovery for... fees charged to its applicants and licensees. The proposed amendments are necessary to implement the...

Buried waste integrated demonstration fiscal year 1992 close-out report

International Nuclear Information System (INIS)

Cannon, P.G.; Kostelnik, K.M.; Owens, K.J.

1993-02-01

The mission of the Buried Waste Integrated Demonstration Program (BWID) is to support the development and demonstration of a suite of technologies that when integrated with commercially-available baseline technologies form a comprehensive remediation system for the effective and efficient remediation of buried waste disposed of throughout the US Department of Energy complex. To accomplish this mission of identifying technological solutions for remediation deficiencies, the Office of Technology Development initiated the BWID at the Idaho National Engineering Laboratory in fiscal year (FY)-91. This report summarizes the activities of the BWID Program during FY-92

Ecological Monitoring and Compliance Program Fiscal Year 1998 Report

International Nuclear Information System (INIS)

Bechtel Nevada Ecological Services

1998-01-01

The Ecological Monitoring and Compliance program, funded through the U. S. Department of Energy/Nevada Operations Office, monitors the ecosystem of the Nevada Test Site and ensures compliance with laws and regulations pertaining to NTS biota. This report summarizes the program's activities conducted by Bechtel Nevada during fiscal year 1998. Twenty-one sites for seven projects were surveyed for the presence of state or federally protected species. Three projects were in or near habitat of the threatened desert tortoise and required special clearance and transect surveys. All geospatial data collected were entered into Bechtel Nevada's Ecological Geographic Information system for use in ongoing ecosystem management of the NTS

Annual report of operation management in nuclear power stations, fiscal year 1985. Showa 60 nendo genshiryoku hatsudensho unten kanri nenpo

Energy Technology Data Exchange (ETDEWEB)

1986-01-01

Twenty years have elapsed since the first practical nuclear reactor in Japan started the operation. In the generated power in fiscal year 1985, that of nuclear power stations for the first time overtook that of thermal power stations, and now the age of nuclear power as the main and oil power as the subordinate has begun. As of the end of fiscal year 1985, there were 32 nuclear power plants in operation, having total output capacity of 24.521 million kW. In fiscal year 1985, nuclear power plants generated about 159 billion kWh, which is about 2 % of electric power supply. As to the capacity factor, 76% was attained in fiscal year 1985, and this is ranked in the top group of LWR-operating countries in the world. It showed that the Japanese technology of nuclear power generation is at the top level in the world. However, in order to increase nuclear power generation and to accomplish the role of main electric power source hereafter, it is necessary to further increase the reliability and economical efficiency. The list of nuclear power stations in Japan, the state of operation of nuclear power stations, the state of accidents and troubles, the state of regular inspection, the management of radioactive wastes and the radiation exposure of workers in nuclear power stations, the operational management and others are reported.

Isolation and characterization of an RIP (ribosome-inactivating protein)-like protein from tobacco with dual enzymatic activity.

Science.gov (United States)

Sharma, Neelam; Park, Sang-Wook; Vepachedu, Ramarao; Barbieri, Luigi; Ciani, Marialibera; Stirpe, Fiorenzo; Savary, Brett J; Vivanco, Jorge M

2004-01-01

Ribosome-inactivating proteins (RIPs) are N-glycosidases that remove a specific adenine from the sarcin/ricin loop of the large rRNA, thus arresting protein synthesis at the translocation step. In the present study, a protein termed tobacco RIP (TRIP) was isolated from tobacco (Nicotiana tabacum) leaves and purified using ion exchange and gel filtration chromatography in combination with yeast ribosome depurination assays. TRIP has a molecular mass of 26 kD as evidenced by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and showed strong N-glycosidase activity as manifested by the depurination of yeast rRNA. Purified TRIP showed immunoreactivity with antibodies of RIPs from Mirabilis expansa. TRIP released fewer amounts of adenine residues from ribosomal (Artemia sp. and rat ribosomes) and non-ribosomal substrates (herring sperm DNA, rRNA, and tRNA) compared with other RIPs. TRIP inhibited translation in wheat (Triticum aestivum) germ more efficiently than in rabbit reticulocytes, showing an IC50 at 30 ng in the former system. Antimicrobial assays using highly purified TRIP (50 microg mL(-1)) conducted against various fungi and bacterial pathogens showed the strongest inhibitory activity against Trichoderma reesei and Pseudomonas solancearum. A 15-amino acid internal polypeptide sequence of TRIP was identical with the internal sequences of the iron-superoxide dismutase (Fe-SOD) from wild tobacco (Nicotiana plumbaginifolia), Arabidopsis, and potato (Solanum tuberosum). Purified TRIP showed SOD activity, and Escherichia coli Fe-SOD was observed to have RIP activity too. Thus, TRIP may be considered a dual activity enzyme showing RIP-like activity and Fe-SOD characteristics.

Summaries of fiscal year 1994 projects in medical applications and biophysical research

International Nuclear Information System (INIS)

1995-04-01

This report provides information on the research supported in Fiscal Year 1994 by the Medical Applications and Biophysical Research Division of the Office of Health and Environmental Research. A brief statement of the scope of the following areas is presented: dosimetry; measurement science; radiological and chemical physics; structural biology; human genome; and medical applications. Summaries of the research projects in these categories are presented

Wastewater treatment plant inspection program, fiscal year 2006 and 2007 data report

OpenAIRE

Greco, Stacie

2008-01-01

This data report includes the results from Alachua County Environmental Protection Department’s inspections of wastewater treatment plants (WWTP) within Alachua County during the 2006 and 2007 fiscal years (October 2005 – September 2007). Groundwater monitoring data provided to the Florida Department of Environmental Protection Department by the WWTP operators is included for those treatment plants that are required to submit this information (PDF has 44 pages.)

76 FR 52006 - Announcement of Funding Awards for the Assisted Living Conversion Program; Fiscal Year 2009

Science.gov (United States)

2011-08-19

... Year 2009 Assisted Living Conversion Program Arizona Phoenix, Kivel Manor, $3,292,367, 15 units... Awards for the Assisted Living Conversion Program; Fiscal Year 2009 AGENCY: Office of the Assistant... funding under the Notice of Funding Availability (NOFA) for the Assisted Living Conversion Program (ALCP...

North Dakota University System Annual Financial Report, Fiscal Year Ended June 30, 2007

Science.gov (United States)

North Dakota University System, 2007

2007-01-01

This report provides financial data for the North Dakota University System (the "System") for the fiscal year ended June 30, 2007. The Management Discussion and Analysis; the Statement of Net Assets; the Statement of Revenues, Expenses, and Changes in Net Assets; and the Statement of Cash Flows provide information on the System as a…

Coupled RipCAS-DFLOW (CoRD) Software and Data Management System for Reproducible Floodplain Vegetation Succession Modeling

Science.gov (United States)

Turner, M. A.; Miller, S.; Gregory, A.; Cadol, D. D.; Stone, M. C.; Sheneman, L.

2016-12-01

We present the Coupled RipCAS-DFLOW (CoRD) modeling system created to encapsulate the workflow to analyze the effects of stream flooding on vegetation succession. CoRD provides an intuitive command-line and web interface to run DFLOW and RipCAS in succession over many years automatically, which is a challenge because, for our application, DFLOW must be run on a supercomputing cluster via the PBS job scheduler. RipCAS is a vegetation succession model, and DFLOW is a 2D open channel flow model. Data adaptors have been developed to seamlessly connect DFLOW output data to be RipCAS inputs, and vice-versa. CoRD provides automated statistical analysis and visualization, plus automatic syncing of input and output files and model run metadata to the hydrological data management system HydroShare using its excellent Python REST client. This combination of technologies and data management techniques allows the results to be shared with collaborators and eventually published. Perhaps most importantly, it allows results to be easily reproduced via either the command-line or web user interface. This system is a result of collaboration between software developers and hydrologists participating in the Western Consortium for Watershed Analysis, Visualization, and Exploration (WC-WAVE). Because of the computing-intensive nature of this particular workflow, including automating job submission/monitoring and data adaptors, software engineering expertise is required. However, the hydrologists provide the software developers with a purpose and ensure a useful, intuitive tool is developed. Our hydrologists contribute software, too: RipCAS was developed from scratch by hydrologists on the team as a specialized, open-source version of the Computer Aided Simulation Model for Instream Flow and Riparia (CASiMiR) vegetation model; our hydrologists running DFLOW provided numerous examples and help with the supercomputing system. This project is written in Python, a popular language in the

A summary report on recruitment type researches on nuclear fuel cycle in fiscal year of 2001

International Nuclear Information System (INIS)

2002-07-01

The promotion system on recruitment type researches on nuclear fuel cycle begun on fiscal year of 1999, aims to intend to activate researching environment of the Japan Nuclear Cycle Development Institute (JNC) through intercourses, information exchanges, publication of research results, and so on between researchers in other organizations and JNC, as a result, to effectively promote fundamental and basic R and Ds. This report contains summaries of 28 items of research results on the recruitment type researches on nuclear fuel cycle as 9 items relating to fast breeder reactors, 8 items relating to nuclear fuel cycle, 1 item relating to radiation safety, and 10 items relating to geological disposal and science, carried out on fiscal year of 2001. (G.K.)

Holographic Ricci dark energy in Randall-Sundrum braneworld: Avoidance of big rip and steady state future

International Nuclear Information System (INIS)

Feng Chaojun; Zhang Xin

2009-01-01

In the holographic Ricci dark energy (RDE) model, the parameter α plays an important role in determining the evolutionary behavior of the dark energy. When α<1/2, the RDE will exhibit a quintom feature, i.e., the equation of state of dark energy will evolve across the cosmological constant boundary w=-1. Observations show that the parameter α is indeed smaller than 1/2, so the late-time evolution of RDE will be really like a phantom energy. Therefore, it seems that the big rip is inevitable in this model. On the other hand, the big rip is actually inconsistent with the theoretical framework of the holographic model of dark energy. To avoid the big rip, we appeal to the extra dimension physics. In this Letter, we investigate the cosmological evolution of the RDE in the braneworld cosmology. It is of interest to find that for the far future evolution of RDE in a Randall-Sundrum braneworld, there is an attractor solution where the steady state (de Sitter) finale occurs, in stead of the big rip.

Tamoxifen-independent recombination in the RIP-CreER mouse.

Directory of Open Access Journals (Sweden)

Yanmei Liu

Full Text Available BACKGROUND: The inducible Cre-lox system is a valuable tool to study gene function in a spatial and time restricted fashion in mouse models. This strategy relies on the limited background activity of the modified Cre recombinase (CreER in the absence of its inducer, the competitive estrogen receptor ligand, tamoxifen. The RIP-CreER mouse (Tg (Ins2-cre/Esr1 1Dam is among the few available β-cell specific CreER mouse lines and thus it has been often used to manipulate gene expression in the insulin-producing cells of the endocrine pancreas. PRINCIPAL FINDINGS: Here, we report the detection of tamoxifen-independent Cre activity as early as 2 months of age in RIP-CreER mice crossed with three distinct reporter strains. SIGNIFICANCE: Evidence of Cre-mediated recombination of floxed alleles even in the absence of tamoxifen administration should warrant cautious use of this mouse for the study of pancreatic β-cells.

Networking and Information Technology Research and Development. Supplement of the President's Budget for Fiscal Year 2006

National Research Council Canada - National Science Library

2005-01-01

This Supplement to the President's Budget for Fiscal Year 2006 offers a brief technical outline of the 2006 budget request for the Networking and Information Technology Research and Development (NITRD) Program...

Muddy and dolomitic rip-up clasts in Triassic fluvial sandstones: Origin and impact on potential reservoir properties (Argana Basin, Morocco)

Science.gov (United States)

Henares, Saturnina; Arribas, Jose; Cultrone, Giuseppe; Viseras, Cesar

2016-06-01

The significance of rip-up clasts as sandstone framework grains is frequently neglected in the literature being considered as accessory components in bulk sandstone composition. However, this study highlights the great value of muddy and dolomitic rip-up clast occurrence as: (a) information source about low preservation potential from floodplain deposits and (b) key element controlling host sandstone diagenetic evolution and thus ultimate reservoir quality. High-resolution petrographic analysis on Triassic fluvial sandstones from Argana Basin (T6 and T7/T8 units) highlights the significance of different types of rip-up clasts as intrabasinal framework components of continental sediments from arid climates. On the basis of their composition and ductility, three main types are distinguished: (a) muddy rip-up clasts, (b) dolomitic muddy rip-up clasts and (c) dolomite crystalline rip-up clasts. Spatial distribution of different types is strongly facies-related according to grain size. Origin of rip-up clasts is related to erosion of coeval phreatic dolocretes, in different development stages, and associated muddy floodplain sediments. Cloudy cores with abundant inclusions and clear outer rims of dolomite crystals suggest a first replacive and a subsequent displacive growth, respectively. Dolomite crystals are almost stoichiometric. This composition is very similar to that of early sandstone dolomite cement, supporting phreatic dolocretes as dolomite origin in both situations. Sandstone diagenesis is dominated by mechanical compaction and dolomite cementation. A direct correlation exists between: (1) muddy rip-up clast abundance and early reduction of primary porosity by compaction with irreversible loss of intergranular volume (IGV); and (2) occurrence of dolomitic rip-up clasts and dolomite cement nucleation in host sandstone, occluding adjacent pores but preserving IGV. Both processes affect reservoir quality by generation of vertical and 3D fluid flow baffles and

Insulin promotes Rip11 accumulation at the plasma membrane by inhibiting a dynamin- and PI3-kinase-dependent, but Akt-independent, internalisation event.

Science.gov (United States)

Boal, Frédéric; Hodgson, Lorna R; Reed, Sam E; Yarwood, Sophie E; Just, Victoria J; Stephens, David J; McCaffrey, Mary W; Tavaré, Jeremy M

2016-01-01

Rip11 is a Rab11 effector protein that has been shown to be important in controlling the trafficking of several intracellular cargoes, including the fatty acid transporter FAT/CD36, V-ATPase and the glucose transporter GLUT4. We have previously demonstrated that Rip11 translocates to the plasma membrane in response to insulin and here we examine the basis of this regulated phenomenon in more detail. We show that Rip11 rapidly recycles between the cell interior and surface, and that the ability of insulin to increase the appearance of Rip11 at the cell surface involves an inhibition of Rip11 internalisation from the plasma membrane. By contrast the hormone has no effect on the rate of Rip11 translocation towards the plasma membrane. The ability of insulin to inhibit Rip11 internalisation requires dynamin and class I PI3-kinases, but is independent of the activation of the protein kinase Akt; characteristics which are very similar to the mechanism by which insulin inhibits GLUT4 endocytosis. Copyright © 2015. Published by Elsevier Inc.

Environmental Information System Baden-Wuerttemberg, RIPS 2016. Spatial information and planning system

International Nuclear Information System (INIS)

Weissenbach, Kurt; Czommer, Olaf; Ellmenreich, Bastian

2016-01-01

The Spatial Information and Planning System (RIPS), as the overarching component of the Environmental Information System Baden-Wuerttemberg (UIS BW), implements the environmental and nature conservation-specific geoinformation-related requirements taking into account applicable framework conditions. To this end, RIPS offers tailor-made services on the basis of a standardized and in transnational cooperation developed technical kit for the areas of geodata processing and management as well as the development and provision of software components with geo-functions and geodata services as part of the technical and information procedures. The coordination and steering takes place via project development offices, working groups and committees in close coordination with the departments of environmental and nature conservation administration as well as further cooperation and in coordination with other specialist administrations. Taking into account changed framework conditions and new geo-referenced requirements in UIS BW, the present RIPS concept focuses on future-oriented geofunction and geodata management in the field of environmental and nature conservation management as well as the provision of geo-specialized environmental and nature conservation data for policy makers, administrators and the public on innovative technologies Applications and Services. [de

U.S. Border Patrol Fiscal Year Statistics Southwest border sector deaths - FY 1998 through FY 2013

Data.gov (United States)

Department of Homeland Security — Southwest Border Sectors include: Del Rio, El Centro, El Paso, Laredo, Rio Grande Valley, San Diego, Tucson, Yuma Southwest Border Deaths By Fiscal Year (Oct. 1st...

42 CFR 457.608 - Process and calculation of State allotments for a fiscal year.

Science.gov (United States)

2010-10-01

... grant for the fiscal year for children with Type I Diabetes under Section 4921 of Public Law 105-33... OF HEALTH AND HUMAN SERVICES (CONTINUED) STATE CHILDREN'S HEALTH INSURANCE PROGRAMS (SCHIPs... State and the District of Columbia with an approved State child health plan, as described in paragraph...

Terry Turbopump Analytical Modeling Efforts in Fiscal Year 2016 ? Progress Report.

Energy Technology Data Exchange (ETDEWEB)

Osborn, Douglas; Ross, Kyle; Cardoni, Jeffrey N

2018-04-01

This document details the Fiscal Year 2016 modeling efforts to define the true operating limitations (margins) of the Terry turbopump systems used in the nuclear industry for Milestone 3 (full-scale component experiments) and Milestone 4 (Terry turbopump basic science experiments) experiments. The overall multinational-sponsored program creates the technical basis to: (1) reduce and defer additional utility costs, (2) simplify plant operations, and (3) provide a better understanding of the true margin which could reduce overall risk of operations.

Äripäev hakkab välja andma PR-ajakirja

Index Scriptorium Estoniae

2012-01-01

Ilmuma hakkas Eesti esimene kommunikatsioonispetsialistidele ja -juhtidele mõeldud erialaajakiri Kaja, mille väljaandja on Äripäeva teabekirjastus koostöös Tallinna Ülikooli kommunikatsiooni instituudiga

Financial audit : District of Columbia highway trust fund's fiscal year 1999 and 1998 financial statements

Science.gov (United States)

2000-10-01

This report presents the results of our audits of the financial statements of the District of Columbia Highway Trust Fund for the fiscal years ended September 30, 1999 and 1998, and our examination of the forecasted statements of the Fund's expected ...

78 FR 6168 - Public Availability of Social Security Administration Fiscal Year (FY) 2012 Service Contract...

Science.gov (United States)

2013-01-29

... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA-2013-0001] Public Availability of Social Security Administration Fiscal Year (FY) 2012 Service Contract Inventory AGENCY: Social Security Administration. ACTION: Notice of Public Availability of FY 2012 Service Contract Inventories. SUMMARY: In accordance with...

77 FR 3836 - Public Availability of Social Security Administration Fiscal Year (FY) 2011 Service Contract...

Science.gov (United States)

2012-01-25

... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA-2011-0105] Public Availability of Social Security Administration Fiscal Year (FY) 2011 Service Contract Inventory AGENCY: Social Security Administration. ACTION: Notice of Public Availability of FY 2011 Service Contract Inventories. SUMMARY: In accordance with...

78 FR 59366 - Multifamily, Healthcare Facilities, and Hospital Mortgage Insurance Premiums for Fiscal Year (FY...

Science.gov (United States)

2013-09-26

... Facilities, and Hospital Mortgage Insurance Premiums for Fiscal Year (FY) 2014 AGENCY: Office of the... with HUD regulations, this Notice announces the mortgage insurance premiums (MIPs) for Federal Housing Administration (FHA) Multifamily, Healthcare Facilities, and Hospital mortgage insurance programs that have...

ANÁLISIS DE LOS REGISTROS INDIVIDUALES DE PRESTACIÓN DE SERVICIOS DE SALUD (RIPS EN CÁNCER EN COLOMBIA

Directory of Open Access Journals (Sweden)

Luz Helena Alba

2016-11-01

Full Text Available

Objetivos: Comparar los registros de atención a pacientes con cáncer en Colombia en el periodo 2009−2013 a través del Registro Individual de Prestación de Servicios de Salud (RIPS, con los registros consignados en la página de la Agencia Internacional Contra el Cáncer: Globocan.

Métodos: Se realizó una búsqueda de información de 27 tipos de cáncer en los RIPS y, a partir de esos datos, se estimaron las tasas de incidencia ajustadas por edad siguiendo la metodología de ajuste directo. Posteriormente, los resultados se compararon con Globocan.

Resultados: Según los RIPS, en el período comprendido entre 2009−2013, se reportaron 110.879 casos incidentes de cáncer; 68.312 en mujeres y 42.509 en hombres. Para la mayoría de los tipos de cáncer se observan tasas de incidencia menores en los registros RIPS respecto a aquellas estimadas por Globocan. De menor a mayor figuran: el cáncer de labio y cavidad oral (0.15:1; próstata (0,33:1; mama (0,74:1; cuello uterino (0,64:1; estómago (0,22:1, colorrectal (0,44:1 y tiroides (0.86:1.

Conclusión: Las diferencias podrían atribuirse a una subestimación presentada en los RIPS; una sobreestimación, en Globocan; o una combinación de las dos. Dada la trayectoria y los mecanismos de verificación de los registros de: Pasto, Cali, Manizales y Bucaramanga, base de la información de Globocan, es probable que los datos de incidencia de los RIPS no se encuentren todavía suficientemente depurados.

ANALYSIS OF INDIVIDUAL RECORDS OF PROVISION OF HEALTH SERVICES (RIPS IN CANCER IN COLOMBIA

ABSTRACT

Objectives: To compare the data for cancer patients care in Colombia during the period 2009- 2013 through the Individual Registration of Health Care Provision (RIPS with records from the International Agency for Research in Cancer (IARC website

California Library Statistics, 2009: Fiscal Year 2007-2008 from Public, Academic, Special and County Law Libraries

Science.gov (United States)

Bray, Ira, Ed.

2009-01-01

Each year the State Library sends annual report forms to California's public, academic, special, state agency, and county law libraries. Statistical data from those reports are tabulated in this publication, with directory listings published in the companion volume, "California Library Directory." For this fiscal year, 389 libraries of…

California Library Statistics, 2005: Fiscal Year 2003-2004 from Public, Academic, Special and County Law Libraries

Science.gov (United States)

Bray, Ira, Ed.

2005-01-01

Each year the State Library sends annual report forms to California's academic, public, special, state agency, and county law libraries. Statistical data from those reports are tabulated in this publication, with directory listings published in the companion volume, California Library Directory. For this fiscal year four hundred and eight…

Results of Detailed Hydrologic Characterization Tests - Fiscal Year 2000

International Nuclear Information System (INIS)

Spane, Frank A; Thorne, Paul D; Newcomer, Darrell R

2001-01-01

This report provides the results of detailed hydrologic characterization tests conducted within eleven Hanford Site wells during fiscal year 2000. Detailed characterization tests performed included groundwater-flow characterization; barometric response evaluation; slug tests; single-well tracer tests; constant-rate pumping tests; and in-well, vertical flow tests. Hydraulic property estimates obtained from the detailed hydrologic tests include transmissivity; hydraulic conductivity; specific yield; effective porosity; in-well, lateral flow velocity; aquifer-flow velocity; vertical distribution of hydraulic conductivity (within the well-screen section); and in-well, vertical flow velocity. In addition, local groundwater-flow characteristics (i.e., hydraulic gradient and flow direction) were determined for four sites where detailed well testing was performed

Ecological Monitoring and Compliance Program Fiscal Year 1998 Report

Energy Technology Data Exchange (ETDEWEB)

Bechtel Nevada Ecological Services

1998-10-01

The Ecological Monitoring and Compliance program, funded through the U. S. Department of Energy/Nevada Operations Office, monitors the ecosystem of the Nevada Test Site and ensures compliance with laws and regulations pertaining to NTS biota. This report summarizes the program's activities conducted by Bechtel Nevada during fiscal year 1998. Twenty-one sites for seven projects were surveyed for the presence of state or federally protected species. Three projects were in or near habitat of the threatened desert tortoise and required special clearance and transect surveys. All geospatial data collected were entered into Bechtel Nevada's Ecological Geographic Information system for use in ongoing ecosystem management of the NTS.

Potentiometric-level monitoring program: Mississippi and Louisiana. Annual status report for fiscal year 1984

International Nuclear Information System (INIS)

1986-07-01

Potentiometric-level data presented in this report were collected from October 1983 through September 1984 at 79 wells in Mississippi and Louisiana. These wells are located near Richton and Cypress Creek Domes in Mississippi and Vacherie Dome in Louisiana. Fourteen wells were added to the program during this period. Two of these wells were not measurable. Two wells previously unmeasurable were located and measured. One well was destroyed during military maneuvers in the area. Analysis of the data indicated minimal, if any, change in potentiometric levels during the past year in the Citronelle, Hattiesburg, Cockfield, Sparta, and Wilcox Formations in Mississippi. A continuing decline in potentiometric levels, ranging from 0.3 to 0.6 foot per year, occurred in the wells screened in the caprock at Richton and Cypress Creek Domes. The Catahoula Formation experienced a continuing decline in potentiometric levels of about 2 feet per year. Two wells in the Cook Mountain Formation showed a continuing rise in potentiometric levels ranging from 8 to 30 ft during the past fiscal year. Wells screened in the Austin Formation in Louisiana showed a fall in potentiometric levels of 2 to 3 ft over the past fiscal year. Other formations in Louisiana generally showed no change in potentiometric levels over the past year. 26 refs., 2 figs., 3 tabs

Äripäev surub end naisteajakirjade turule / Krista Taim

Index Scriptorium Estoniae

Taim, Krista

2005-01-01

Äripäev hakkab välja andma naisteajakirja Dilemma, lootes saada viiendiku reklaamiturust. Diagramm: Naisteajakirjade reklaamituru jagunemine. Vt. samas: Dilemma hakkab ilmuma kaheksa korda aastas; Eesti Päevaleht ja Eesti Meedia hakkavad tasuta ajalehte välja andma

Financial Audit: Bureau of the Public Debt's Fiscal Years 2001 and 2000 Schedules of Federal Debt

National Research Council Canada - National Science Library

2002-01-01

The accompanying auditor's report presents the results of our audits of the Schedules of Federal Debt Managed by the Bureau of the Public Debt for the fiscal years ended September 30, 2001 and 2000...

77 FR 38274 - Availability of the Fiscal Year 2011 United States Special Operations Command (USSOCOM) Inventory...

Science.gov (United States)

2012-06-27

... Authorization Act for Fiscal Year 2012, the Director of Procurement USSOCOM and the Office of the Director... inventory will be published to the USSOCOM public portal Web site at the following location: http://www...

78 FR 25515 - Order Making Fiscal Year 2013 Annual Adjustments to Transaction Fee Rates

Science.gov (United States)

2013-05-01

... collected under Section 31(d) of the Exchange Act for all of fiscal year 2013 \\8\\ from an amount equal to... Act of 1934 (``Exchange Act'') requires each national securities exchange and national securities association to pay transaction fees to the Commission.\\1\\ Specifically, Section 31(b) requires each national...

42 CFR 412.210 - Puerto Rico rates for Federal fiscal years 1989 through 2003.

Science.gov (United States)

2010-10-01

...) Geographic classifications. (1) For purposes of this section, the definitions set forth in § 412.208(f)(1... of final standards for classification of MSAs published in the Federal Register on January 3, 1980... discharge classified within a DRG, CMS establishes for the fiscal year a Puerto Rico prospective payment...

76 FR 54193 - Fiscal Year 2012 Veterinary Import/Export, Diagnostic Services, and Export Certification for...

Science.gov (United States)

2011-08-31

...] Fiscal Year 2012 Veterinary Import/Export, Diagnostic Services, and Export Certification for Plants and.... SUMMARY: This notice pertains to user fees charged for Veterinary Services animal quarantine and other..., organisms, and vectors; for certain veterinary diagnostic services; and for export certification of plants...

40 CFR 35.910-12 - Reallotment of deobligated funds of Fiscal Year 1978.

Science.gov (United States)

2010-07-01

...-Clean Water Act § 35.910-12 Reallotment of deobligated funds of Fiscal Year 1978. (a) Of the 4.5 billion... 1,312,681 Indiana 699,465 Iowa 327,345 Kansas 222,494 Kentucky 369,430 Louisiana 319,073 Maine 189... Missouri 630,710 Montana 118,190 Nebraska 139,138 Nevada 118,190 New Hampshire 222,653 New Jersey 902,590...

Fusion Safety Program annual report, fiscal year 1984

International Nuclear Information System (INIS)

Crocker, J.G.; Holland, D.F.

1985-06-01

This report summarizes the Fusion Safety Program major activities in fiscal year 1984. The Idaho National Engineering Laboratory (INEL) is the designated lead laboratory and EG and G Idaho, Inc., is the prime contractor for this program, which was initiated in 1979. A report section titled ''Activities at the INEL'' includes progress reports on the tritium implantation experiment, tritium blanket permeation, volatilization of reactor alloys, plasma disruptions, a comparative blanket safety assessment, transient code development, and a discussion of the INEL's participation in the Tokamak Fusion Core Experiment (TFCX) design study. The report section titled ''Outside Contracts'' includes progress reports on tritium conversion by the Oak Ridge National Laboratory (ORNL), lithium-lead reactions by the Hanford Engineering Development Laboratory (HEDL) and the University of Wisconsin, magnet safety by the Francis Bitter Magnet Laboratory of the Massachusetts Institute of Technology (MIT) and Argonne National Laboratory (ANL), risk assessment by MIT, tritium retention by the University of Virginia, and activation product release by GA Technologies. A list of publications produced during the year and brief descriptions of activities planned for FY-1985 are also included

Revenues and Expenditures for Public Elementary and Secondary School Districts: School Year 2008-09 (Fiscal Year 2009). First Look. NCES 2012-313

Science.gov (United States)

Cornman, Stephen Q.; Noel, Amber M.

2011-01-01

This report presents data from the School District Finance Survey (F-33) of the Common Core of Data (CCD) survey system for school year (SY) 2008-09 (fiscal year [FY] 2009). The F-33 is a district-level financial survey that consists of data submitted annually to the National Center for Education Statistics (NCES) and the Governments Division of…

Maintenance of the Hanford cone penetrometer platform during fiscal year 1999

International Nuclear Information System (INIS)

IWATATE, D.F.

1998-01-01

This SOW describes services requested of Applied Research and Associates, Inc. (ARA), as a commercial provider of cone penetrometer equipment and services, to provide routine inspection and minimum preventive maintenance on the Hanford CP Platform (CPP) during Fiscal Year 1999. This SOW specifically pertains to the maintenance of the CPP and associated support equipment and is limited in scope to routine preventive maintenance and identification of any deficiencies. ARA is the original manufacturer of the CPP and will conduct this work following the vendor-prepared maintenance schedule

Annual report of nuclear code evaluation committee for fiscal 2000 year

Energy Technology Data Exchange (ETDEWEB)

NONE

2002-03-01

In this report, research results discussed in fiscal 2000 year at Nuclear Code Evaluation Committee of Nuclear Code Research Committee were summarized. In 2000, papers mainly on the three topics of (1) present status of burnup credit evaluation methods, (2) issues concerning convergence of criticality calculation and (3) estimation methods for errors associated with criticality calculation based on nuclear data covariance file, are presented and discussed. These results are sorted to grasp the present status of related technology and described in this report. (author)

Brookhaven highlights for fiscal year 1991, October 1, 1990--September 30, 1991

Energy Technology Data Exchange (ETDEWEB)

Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L.; Kuper, J.B.H.

1991-01-01

This report highlights Brookhaven National Laboratory's activities for fiscal year 1991. Topics from the four research divisions: Computing and Communications, Instrumentation, Reactors, and Safety and Environmental Protection are presented. The research programs at Brookhaven are diverse, as is reflected by the nine different scientific departments: Accelerator Development, Alternating Gradient Synchrotron, Applied Science, Biology, Chemistry, Medical, National Synchrotron Light Source, Nuclear Energy, and Physics. Administrative and managerial information about Brookhaven are also disclosed. (GHH)

Brookhaven highlights for fiscal year 1991, October 1, 1990--September 30, 1991

Energy Technology Data Exchange (ETDEWEB)

Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L.; Kuper, J.B.H.

1991-12-31

This report highlights Brookhaven National Laboratory`s activities for fiscal year 1991. Topics from the four research divisions: Computing and Communications, Instrumentation, Reactors, and Safety and Environmental Protection are presented. The research programs at Brookhaven are diverse, as is reflected by the nine different scientific departments: Accelerator Development, Alternating Gradient Synchrotron, Applied Science, Biology, Chemistry, Medical, National Synchrotron Light Source, Nuclear Energy, and Physics. Administrative and managerial information about Brookhaven are also disclosed. (GHH)

Brookhaven highlights for fiscal year 1991, October 1, 1990--September 30, 1991

International Nuclear Information System (INIS)

Rowe, M.S.; Cohen, A.; Greenberg, D.; Seubert, L.; Kuper, J.B.H.

1991-01-01

This report highlights Brookhaven National Laboratory's activities for fiscal year 1991. Topics from the four research divisions: Computing and Communications, Instrumentation, Reactors, and Safety and Environmental Protection are presented. The research programs at Brookhaven are diverse, as is reflected by the nine different scientific departments: Accelerator Development, Alternating Gradient Synchrotron, Applied Science, Biology, Chemistry, Medical, National Synchrotron Light Source, Nuclear Energy, and Physics. Administrative and managerial information about Brookhaven are also disclosed

78 FR 54656 - Fee for Using a Priority Review Voucher in Fiscal Year 2014

Science.gov (United States)

2013-09-05

.... currency by check, bank draft, or U.S. postal money order payable to the order of the Food and Drug... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0007] Fee for Using a Priority Review Voucher in Fiscal Year 2014 AGENCY: Food and Drug Administration, HHS...

Fiscal Transparency and Procyclical Fiscal Policy

DEFF Research Database (Denmark)

Andersen, Asger Lau; Nielsen, Lasse Holbøll Westh

This paper examines why fiscal policy is procyclical in developing as well as developed countries. We introduce the concept of fiscal transparency into a model of retrospective voting, in which a political agency problem between voters and politicians generates a procyclical bias in government...... spending. The introduction of fiscal transparency generates two new predictions: 1) the procyclical bias in fiscal policy arises only in good times; and 2) a higher degree of fiscal transparency reduces the bias in good times. We find solid empirical support for both predictions using data on both OECD...

75 FR 61167 - Notice of Availability: Notice of Funding Availability (NOFA) for HUD's Fiscal Year (FY) 2010...

Science.gov (United States)

2010-10-04

... participating in HUD's Housing Counseling Program, including HUD-approved agencies, affiliates and branches of...: Notice of Funding Availability (NOFA) for HUD's Fiscal Year (FY) 2010 Housing Counseling Training Program... requirements for HUD's Housing Counseling Training Program NOFA for FY2010. This year's Housing Counseling...

Annual report of National Institute of Radiological Sciences of the fiscal year 1983

International Nuclear Information System (INIS)

1984-10-01

The activities of the National Institute of Radiological Sciences in fiscal year 1983 were carried out on the basis of the total budget of 5,835,354,000 yen and 412 staffs. In spite of the severe situation of administrative reform of the government, the works were accomplished, and the considerable results were obtained. Ordinary research was carried out on 63 subjects. Special research was carried out on four themes, that is, the biological effect of tritium accompanying the development of nuclear fusion reactors, the medical utilization of particle accelerators, the probabilistic effect and risk evaluation of radiation, and the evaluation of exposure to environmental radiation. In addition, specified research was carried out on three subjects. The number of trainees who finished various courses in the Training Division reached 3290 in fiscal year 1983, and it greatly contributed to the radiation protection and the utilization of radiation in Japan. The importance of the international exchange has increased, and the staffs attended various international meetings and exchanged opinion with visitors. Investigation and research works, technical assistance, training, medical treatment, the administration of Nakaminato Branch Office, book and editorial works and general affairs are reported. (Kako, I.)

Annual report of National Institute of Radiological Sciences of the fiscal year 1980

International Nuclear Information System (INIS)

1981-10-01

This report covers the period from April 1, 1980, to March 31, 1981, and the information on the research carried out by the staffs of the institute during this period is given. The total budget for the fiscal year 1980 was about 4,475 million yen including personnel costs. Besides basic research, three long term projects have been carried on, i.e. the risk assessment on low level radiation, the research on the exposure to environmental radiation caused by nuclear facilities and others and the medical application of a particle accelerator. In connection with the project on the risk assessment of low level radiation, a new laboratory for the research on internal radiation effect has been constructed since 1979, and is expected to be completed in the fiscal year 1983. These three projects have progressed satisfactorily. In this report, the summaries of 14 papers on physics, 7 papers on chemistry, 12 papers on biochemistry and biophysics, 8 papers on cytology and morphology, 8 papers on physiology, 7 papers on genetics, 5 papers on immunology and hematology, 9 papers on medical studies and 22 papers on environmental studies are collected. (Kako, I.)

Annual report of National Institute of Radiological Sciences of the fiscal year 1984

International Nuclear Information System (INIS)

1985-09-01

The activities of National Institute of Radiological sciences in fiscal year 1984 were carried out on the basis of the total budget of 6052 million yen and 408 regular staffs. The ordinary research is the base of all research activities, and was carried out on 62 subjects, which achieved the results of internationally high level. The special research was performed by selecting four themes, that is, the investigation and research on the biological effect of tritium accompanying the development of nuclear fusion, the investigation and research on the probabilistic effect of radiation and risk evaluation, the investigation and research on the evaluation of environmental radiation exposure, and the investigation and research on the medical utilization of heavy particle beam and others. In addition, the specified research and the research using the science and technology promotion coordination expense were carried out. The total number of trainees who have finished various courses of the Education and Training Division reached 3466 in fiscal year 1984, and those contributed largely to the protection and utilization of radiation in Japan. Effort was exerted to promote the international exchange in this field. The activities in respective divisions are reported. (Kako, I.)

Department of Defense Fiscal Years 1990 and 1991 Budget Revision

Science.gov (United States)

1989-04-01

Japan Yen 123.52 132.61 Netherlands Guilder 1.97 2.13 Norway Krone 6.61 6.87 Portugal Escudo 144.99 156.20 South Korea Won 697.84 669.34 Spain Peseta...and the continental United States. In addition, due to fiscal constraints, one active component AH-I helicopter battalion will be inactivated in FY...1992 due to fiscal constraints. In addition, retirement of 14 of the DDG-2 and DDG-37 class destroyers will be accelerated with an additional 9 in FY

Isotope production and distribution Programs Fiscal Year (FY) 1995 Financial Statement Audit (ER-FC-96-01)

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-02-12

The charter of the Department of Energy (DOE) Isotope Production and Distribution Program (Isotope Program) covers the production and sale of radioactive and stable isotopes, associated byproducts, surplus materials such as lithium and deuterium, and related isotope services. Services provided include, but are not limited to, irradiation services, target preparation and processing, source encapsulation and other special preparations, analyses, chemical separations, and leasing of stable isotopes for research purposes. Isotope Program products and services are sold worldwide for use in a wide variety of research, development, biomedical, and industrial applications. The Isotope Program reports to the Director of the Office of Nuclear Energy, Science and Technology. The Isotope Program operates under a revolving fund, as established by the Fiscal Year 1990 Energy and Water Appropriations Act (Public Law 101-101). The Fiscal Year 1995 Appropriations Act (Public Law 103-316) modified predecessor acts to allow prices charged for Isotope Program products and services to be based on production costs, market value, the needs of the research community, and other factors. Prices set for small-volume, high-cost isotopes that are needed for research may not achieve full-cost recovery. Isotope Program costs are financed by revenues from the sale of isotopes and associated services and through payments from the isotope support decision unit, which was established in the DOE fiscal year 1995 Energy, Supply, Research, and Development appropriation. The isotope decision unit finances the production and processing of unprofitable isotopes that are vital to the national interest.

Revenues and Expenditures for Public Elementary and Secondary School Districts: School Year 2009-10 (Fiscal Year 2010): First Look. NCES 2013-307

Science.gov (United States)

Cornman, Stephen Q.

2013-01-01

This report presents data from the School District Finance Survey (F-33) of the Common Core of Data (CCD) survey system for school year (SY) 2009-10, fiscal year 2010 (FY 10). The F-33 is a district-level financial survey that consists of data submitted annually to the National Center for Education Statistics (NCES) and the Governments Division of…

Annual Hanford Seismic Report for Fiscal Year 2010

Energy Technology Data Exchange (ETDEWEB)

Rohay, Alan C.; Clayton, Ray E.; Sweeney, Mark D.; Devary, Joseph L.; Hartshorn, Donald C.

2010-12-27

The Hanford Seismic Assessment Program (HSAP) provides an uninterrupted collection of high-quality raw and processed seismic data from the Hanford Seismic Network for the U.S. Department of Energy and its contractors. The HSAP is responsible for locating and identifying sources of seismic activity and monitoring changes in the historical pattern of seismic activity at the Hanford Site. The data are compiled, archived, and published for use by the Hanford Site for waste management, natural phenomena hazards assessments, and engineering design and construction. In addition, the HSAP works with the Hanford Site Emergency Services Organization to provide assistance in the event of a significant earthquake on the Hanford Site. The Hanford Seismic Network and the Eastern Washington Regional Network consist of 44 individual sensor sites and 15 radio relay sites maintained by the Hanford Seismic Assessment Team. During FY 2010, the Hanford Seismic Network recorded 873 triggers on the seismometer system, which included 259 seismic events in the southeast Washington area and an additional 324 regional and teleseismic events. There were 210 events determined to be local earthquakes relevant to the Hanford Site. One hundred and fifty-five earthquakes were detected in the vicinity of Wooded Island, located about eight miles north of Richland just west of the Columbia River. The Wooded Island events recorded this fiscal year were a continuation of the swarm events observed during fiscal year 2009 and reported in previous quarterly and annual reports (Rohay et al. 2009a, 2009b, 2009c, 2010a, 2010b, and 2010c). Most events were considered minor (coda-length magnitude [Mc] less than 1.0) with the largest event recorded on February 4, 2010 (3.0Mc). The estimated depths of the Wooded Island events are shallow (averaging approximately 1.5 km deep) placing the swarm within the Columbia River Basalt Group. Based upon the last two quarters (Q3 and Q4) data, activity at the Wooded Island

Fuels and Materials Division biennial report, fiscal years 1979 and 1980

International Nuclear Information System (INIS)

Brown, H.L.

1980-10-01

The Fuels and Materials Division of EG and G Idaho, Inc., reports its technical activities for the fiscal years 1979 to 1980. This Division supports technical programs at the Idaho National Engineering Laboratory with materials science, materials engineering, nondestructive evaluation engineering, and remote handling of radioactive and other hazardous materials and conducts several direct-funded materials-related programs for the US Department of Energy. This report details programmatic and other support activities, direct-funded programs, organization and facility status, and EG and G Idaho-funded technical development programs

Examination concerning application of ACROSS to engineering technology of the MIU project. Annual report, fiscal year 2008

International Nuclear Information System (INIS)

Hasegawa, Ken; Kunitomo, Takahiro; Nakajima, Takahiro; Asai, Hideaki; Iyatomi, Yohsuke; Matsui, Hiroya

2010-01-01

ACROSS (Accurately Controlled Routinely Operated Signal System) has developed to acquire the detailed information on the tectonically active zone. The technology for example the transmission and receiving technique, the data analysis and the interpretation technique of the ACROSS signal, is able to apply not only to seismology but also to other field. We consider the ACROSS technology may apply to the engineering technology of the MIU project, for example monitoring of the change of the geological environment around shafts and also the strength of the shaft concrete itself. It is planned that the examination for three years will be made from fiscal year 2007. The first year is expansion of the network of observation stations, the second year is data acquisition and last year is the analysis of data and evaluation of the ACROSS. In this report, we describe the results of fundamental studies of the ACROSS and the preliminary processing results obtained from the ACROSS observation stations which were prepared in fiscal year 2007 and 2008. (author)

New Madrid seismotectonic study. Activities during fiscal year 1982

International Nuclear Information System (INIS)

Buschbach, T.C.

1984-04-01

The New Madrid Seismotectonic Study is a coordinated program of geological, geophysical, and seismological investigations of the area within a 200-mile radius of New Madrid, Missouri. The study is designed to define the structural setting and tectonic history of the area in order to realistically evaluate earthquake risks in the siting of nuclear facilities. Fiscal year 1982 included geological and geophysical studies aimed at better definition of the east-west trending fault systems - the Rough Creek and Cottage Grove systems - and the northwest-trending Ste. Genevieve faulting. A prime objective was to determine the nature and history of faulting and to establish the relationship with that faulting and the northeast-trending faults of the Wabash Valley and New Madrid areas. 27 references, 61 figures

THE GENERAL ATOMICS FUSION THEORY PROGRAM ANNUAL REPORT FOR FISCAL YEAR 2002

International Nuclear Information System (INIS)

PROJECT STAFF

2002-01-01

OAK B202 THE GENERAL ATOMICS FUSION THEORY PROGRAM ANNUAL REPORT FOR FISCAL YEAR 2002. The dual objective of the fusion theory program at General Atomics (GA) is to significantly advance the scientific understanding of the physics of fusion plasmas and to support the DIII-D and other tokamak experiments. The program plan is aimed at contributing significantly to the Fusion Energy Science and the Tokamak Concept Improvement goals of the Office of Fusion Energy Sciences (OFES)

Revenues and Expenditures for Public Elementary and Secondary Education: School Year 2011-12 (Fiscal Year 2012). First Look. NCES 2014-301

Science.gov (United States)

Cornman, Stephen Q.

2015-01-01

This First Look report introduces new data for national and state-level public elementary and secondary revenues and expenditures for fiscal year (FY) 2012. Specifically, this report includes findings from the following types of school finance data: (1) Revenue and expenditure totals; (2) Revenues by source; (3) Expenditures by function and…

Revenues and Expenditures for Public Elementary and Secondary Education: School Year 2014-15 (Fiscal Year 2015). First Look. NCES 2018-301

Science.gov (United States)

Cornman, Stephen Q.; Zhou, Lei; Howell, Malia R.; Young, Jumaane

2018-01-01

This First Look report introduces new data for national and state-level public elementary and secondary revenues and expenditures for fiscal year (FY) 2015. Specifically, this report includes the following school finance data: (1) revenue and expenditure totals; (2) revenues by source; (3) expenditures by function and object; (4) current…

75 FR 55589 - Fee for Using a Priority Review Voucher in Fiscal Year 2011

Science.gov (United States)

2010-09-13

... determined each fiscal year (FY) based on the average cost incurred by FDA in the review of a human drug... cost incurred by FDA in the review of a human drug application subject to priority review in the... the fee amount should be based on the average cost incurred by the Agency for a priority review in the...

Office of Civilian Radioactive Waste Management Fiscal Year 1994 annual report to Congress

International Nuclear Information System (INIS)

1995-05-01

The events of Fiscal Year 1994 made it a notable year in OCRWN's history. Highlights include formulation of a new program approach; intensive consultation with other parties to build confidence in that approach; the delivery, assembly, and initial testing of the tunnel boring machine that is now digging into Yucca Mountain; steps toward acquisition of a standardized multipurpose canister system and planning for the accompanying environmental impact statement; and solicitation, through a Federal Register notice, of utilities' and other interested parties' recommendations toward resolving key waste-acceptance issues

Office of Civilian Radioactive Waste Management Fiscal Year 1994 annual report to Congress

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-05-01

The events of Fiscal Year 1994 made it a notable year in OCRWN`s history. Highlights include formulation of a new program approach; intensive consultation with other parties to build confidence in that approach; the delivery, assembly, and initial testing of the tunnel boring machine that is now digging into Yucca Mountain; steps toward acquisition of a standardized multipurpose canister system and planning for the accompanying environmental impact statement; and solicitation, through a Federal Register notice, of utilities` and other interested parties` recommendations toward resolving key waste-acceptance issues.

78 FR 46955 - Animal Drug User Fee Rates and Payment Procedures for Fiscal Year 2014

Science.gov (United States)

2013-08-02

... courier such as Federal Express or United Parcel Service, the courier may deliver the check and printed... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0007] Animal Drug User Fee Rates and Payment Procedures for Fiscal Year 2014 AGENCY: Food and Drug...

Fiscal councils as a mechanism for establishing fiscal discipline

Directory of Open Access Journals (Sweden)

Anđelković Mileva

2014-01-01

Full Text Available Under the impact of the global economic crisis, the contemporary budget systems have been subject to extensive reforms. There is a growing number of scholars advocating the establishment of fully independent fiscal institutions which would be in charge of administering a sustainable fiscal policy. The bodies available in hitherto practice are fiscal councils, parliament committees on budgetary control or fiscal 'watchdogs'. The institutionalization of fiscal councils should provide for improving the quality of the public debate on fiscal policy and make the governments more fiscally accountable. The existing fiscal councils generally have an advisory role and they are expected to contribute to strengthening the role of national parliaments in scrutinizing the national budget. In fact, the establishment of fiscal councils ensues only after introducing the fiscal rules which serve as statutory limitations on the activities of the executive branch in the budget-related matters. The current economic crisis has substantially hindered the efficient application of these fiscal restrictions. Some states see the solution in establishing independent fiscal institutions which would control the compliance with these rules. As one of the participants in the budgetary process, fiscal councils are in a position to provide better information to the voters on the current state of affairs in public finances and (thus increase the political costs of the government's fiscal unaccountability. In practice, there are several models for the organization of fiscal councils which primarily focus on ex ante or ex post review and assessment concerning whether the relevant institutions have observed the fiscal rules and accomplished the fiscal goals. Considering that their role is to eliminate the asymmetry of information in relations between the legislative and executive breach of government, fiscal councils should contribute to reinforcing the legitimacy of the budgetary

Liaison activities with the Institute of Physical Chemistry/Russian Academy of Science Fiscal Year 1995

International Nuclear Information System (INIS)

Delegard, C.H.

1995-09-01

Investigations into the chemistry of alkaline Hanford Site tank waste (TTP RL4-3-20-04) were conducted in Fiscal Year 1995 at Westinghouse Hanford Company under the support of the Efficient Separations and Processing Crosscutting Program (EM-53). The investigation had two main subtasks: liaison with the Institute of Physical Chemistry of the Russian Academy of Science and further laboratory testing of the chemistry of thermal reconstitution of Hanford Site tank waste. Progress, which was achieved in the liaison subtask during Fiscal Year 1995, is summarized as follows: (1) A technical dialogue has been established with Institute scientists. (2) Editing was done on a technical literature review on the chemistry of transuranic elements and technetium in alkaline media written by researchers at the Institute. The report was issued in May 1995 as a Westinghouse Hanford Company document. (3) Four tasks from the Institute were selected for support by the U.S. Department of Energy. Work on three tasks commenced on 1 March 1995; the fourth task commenced on 1 April 1995. (4) Technical information describing the composition of Hanford Site tank waste was supplied to the Institute. (5) A program review of the four tasks was conducted at the Institute during a visit 25 August to 1 September, 1995. A lecture on the origin, composition, and proposed treatment of Hanford Site tank wastes was presented during this visit. Eight additional tasks were proposed by Institute scientists for support in Fiscal Year 1996. (6) A paper was presented at the Fifth International Conference on Radioactive Waste Management and Environmental Remediation (ICEM'95) in Berlin, Germany on 3 to 9 September, 1995 on the solubility of actinides in alkaline media

Federal Geothermal Research Program Update Fiscal Year 1999

Energy Technology Data Exchange (ETDEWEB)

2004-02-01

The Department of Energy (DOE) and its predecessors have conducted research and development (R&D) in geothermal energy since 1971. To develop the technology needed to harness the Nation's vast geothermal resources, DOE's Office of Geothermal and Wind Technologies oversees a network of national laboratories, industrial contractors, universities, and their subcontractors. The following mission and goal statements guide the overall activities of the Office of Geothermal and Wind Technologies. This Federal Geothermal Program Research Update reviews the specific objectives, status, and accomplishments of DOE's Geothermal Program for Federal Fiscal Year (FY) 1999. The information contained in this Research Update illustrates how the mission and goals of the Office of Geothermal and Wind Technologies are reflected in each R&D activity. The Geothermal Program, from its guiding principles to the most detailed research activities, is focused on expanding the use of geothermal energy.

ASSESSMENT OF RIP-V1 AND OSPF-V2 PROTOCOL WITH CONSIDERATION OF CONVERGENCE CRITERIA AND SENDING PROTOCOLS TRAFFIC

Directory of Open Access Journals (Sweden)

Hamed Jelodar

2014-03-01

Full Text Available Routing Protocols are underlying principles in networks like internet, transport and mobile. Routing Protocols include a series of rules and algorithms that consider routing metric and select the best way for sending healthy data packets from origin to destination. Dynamic routing protocol compatible to topology has a changeable state. RIP and OSPF are dynamic routing protocol that we consider criteria like convergence and sending protocols traffic assessment RIP first version and OSPF second version. By the test we have done on OPNET stimulation we understood that the OSPF protocol was more efficient than RIP protocol.

Revenues and Expenditures for Public Elementary and Secondary Education: School Year 2012-13 (Fiscal Year 2013). First Look. NCES 2015-301

Science.gov (United States)

Cornman, Stephen Q.

2016-01-01

This First Look report introduces new data for national and state-level public elementary and secondary revenues and expenditures for fiscal year 2013 (FY 13). Specifically, this report includes findings from the following types of school finance data: (1) revenue and expenditure totals; (2) revenues by source; (3) expenditures by function and…

Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation.

Science.gov (United States)

Ruggiero, Alessia; Marasco, Daniela; Squeglia, Flavia; Soldini, Silvia; Pedone, Emilia; Pedone, Carlo; Berisio, Rita

2010-09-08

Cell separation depends on cell-wall hydrolases that cleave the peptidoglycan layer connecting daughter cells. In Mycobacterium tuberculosis, this process is governed by the predicted endopeptidase RipA. In the absence of this enzyme, the bacterium is unable to divide and exhibits an abnormal phenotype. We here report the crystal structure of a relevant portion of RipA, containing its catalytic-domain and an extra-domain of hitherto unknown function. The structure clearly demonstrates that RipA is produced as a zymogen, which needs to be activated to achieve cell-division. Bacterial cell-wall degradation assays and proteolysis experiments strongly suggest that activation occurs via proteolytic processing of a fully solvent exposed loop identified in the crystal structure. Indeed, proteolytic cleavage at this loop produces an activated form, consisting of the sole catalytic domain. Our work provides the first evidence of self-inhibition in cell-disconnecting enzymes and opens a field for the design of novel antitubercular therapeutics. Copyright © 2010 Elsevier Ltd. All rights reserved.

Pillow seal system at the BigRIPS separator

Energy Technology Data Exchange (ETDEWEB)

Tanaka, K., E-mail: ktanaka@riken.jp; Inabe, N.; Yoshida, K.; Kusaka, K.; Kubo, T.

2013-12-15

Highlights: • Pillow seal system has been installed for a high-intensity RI-beam facility at RIKEN. • It is aimed at facilitating remote maintenance under high residual radiation. • Local radiation shields are integrated with one of the pillow seals. • Pillow seals have been aligned to the beam axis within 1mm accuracy. • A leakage rate of 10{sup –9} Pa m{sup 3}/s has been achieved with our pillow seal system. -- Abstract: We have designed and installed a pillow seal system for the BigRIPS fragment separator at the RIKEN Radioactive Isotope Beam Factory (RIBF) to facilitate remote maintenance in a radioactive environment. The pillow seal system is a device to connect a vacuum chamber and a beam tube. It allows quick attachment and detachment of vacuum connections in the BigRIPS separator and consists of a double diaphragm with a differential pumping system. The leakage rate achieved with this system is as low as 10{sup –9} Pa m{sup 3}/s. We have also designed and installed a local radiation-shielding system, integrated with the pillow seal system, to protect the superconducting magnets and to reduce the heat load on the cryogenic system. We present an overview of the pillow seal and the local shielding systems.

Environmental Management Science Program awards. Fiscal year 1997 annual progress report

Energy Technology Data Exchange (ETDEWEB)

Simmons, A. [ed.; Benner, W.H.; DePaolo, D.J.; Faybishenko, B.; Majer, E.L.; Pallavicini, M.; Russo, R.E.; Shultz, P.G.; Wan, J.

1997-10-01

Lawrence Berkeley National Laboratory was awarded eight Environmental Management Science Program (EMSP) research grants in Fiscal Year 1996. This report summarizes the progress of each grant in addressing significant DOE site cleanup issues after completion of the first year of research. The technical progress made to date in each of the research projects is described in greater detail in individual progress reports. The focus of the research projects covers a diversity of areas relevant to site cleanup, including bioremediation, health effects, characterization, and mixed waste. Some of the projects cut across a number of focus areas. Three of the projects are directed toward characterization and monitoring at the Idaho National Engineering and Environmental Laboratory, as a test case for application to other sites.

Environmental Management Science Program awards. Fiscal year 1997 annual progress report

International Nuclear Information System (INIS)

Simmons, A.; Benner, W.H.; DePaolo, D.J.; Faybishenko, B.; Majer, E.L.; Pallavicini, M.; Russo, R.E.; Shultz, P.G.; Wan, J.

1997-10-01

Lawrence Berkeley National Laboratory was awarded eight Environmental Management Science Program (EMSP) research grants in Fiscal Year 1996. This report summarizes the progress of each grant in addressing significant DOE site cleanup issues after completion of the first year of research. The technical progress made to date in each of the research projects is described in greater detail in individual progress reports. The focus of the research projects covers a diversity of areas relevant to site cleanup, including bioremediation, health effects, characterization, and mixed waste. Some of the projects cut across a number of focus areas. Three of the projects are directed toward characterization and monitoring at the Idaho National Engineering and Environmental Laboratory, as a test case for application to other sites

Activity report on the utilization of research reactors. Japanese Fiscal Year, 1998

Energy Technology Data Exchange (ETDEWEB)

Toyoda, Masayuki; Koyama, Yoshimi [eds.; Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

2000-03-01

This is the second issue of the activity report on the utilization of research reactors in the fields of neutron beam experiments, neutron activation analysis, radioisotope production, etc., performed during Japanese Fiscal Year 1998 (April 1, 1998 - March 31, 1999). All reports in this volume were described by users from JAERI and also users from the other organizations, i.e., universities, national research institutes and private companies, who have utilized our research reactor utilization facilities for the purpose of the above studies. (author)

Activity report on the utilization of research reactors. Japanese Fiscal Year, 1999

International Nuclear Information System (INIS)

Toyoda, Masayuki

2001-03-01

This is the second issue of the activity report on the utilization of research reactors in the fields of neutron beam experiments, neutron activation analysis, radioisotope production, etc., performed during Japanese Fiscal Year 1999 (April 1, 1999 - March 31, 2000). All reports in this volume were described by users from JAERI and also users from the other organizations, i.e., universities, national research institutes and private companies, who have utilized our research reactor utilization facilities for the purpose of the above studies. (author)

Notification: Background Investigation Services Audits of EPA’s Fiscal Year 2015 FIFRA and PRIA Financial Statements

Science.gov (United States)

Projects #OA-FY16-0080 and #OA-FY16-0079, February 8, 2016. EPA OIG plan to begin audits of the EPA's fiscal year (FY) 2015 financial statements for the Pesticides Reregistration and Expedited Processing Fund (FIFRA) and Pesticide Registration Fund (PRIA).

76 FR 2135 - Office of Juvenile Justice and Delinquency Prevention Proposed Plan for Fiscal Year 2011

Science.gov (United States)

2011-01-12

... DEPARTMENT OF JUSTICE Office of Juvenile Justice and Delinquency Prevention [OJP (OJJDP) Docket No. 1544] Office of Juvenile Justice and Delinquency Prevention Proposed Plan for Fiscal Year 2011 AGENCY: Office of Juvenile Justice and Delinquency Prevention, Office of Justice Programs, Department of Justice...

Fusion Safety Program annual report, fiscal year 1994

International Nuclear Information System (INIS)

Longhurst, G.R.; Cadwallader, L.C.; Dolan, T.J.; Herring, J.S.; McCarthy, K.A.; Merrill, B.J.; Motloch, C.G.; Petti, D.A.

1995-03-01

This report summarizes the major activities of the Fusion Safety Program in fiscal year 1994. The Idaho National Engineering Laboratory (INEL) is the designated lead laboratory and Lockheed Idaho Technologies Company is the prime contractor for this program. The Fusion Safety Program was initiated in 1979. Activities are conducted at the INEL, at other DOE laboratories, and at other institutions, including the University of Wisconsin. The technical areas covered in this report include tritium safety, beryllium safety, chemical reactions and activation product release, safety aspects of fusion magnet systems, plasma disruptions, risk assessment failure rate data base development, and thermalhydraulics code development and their application to fusion safety issues. Much of this work has been done in support of the International Thermonuclear Experimental Reactor (ITER). Also included in the report are summaries of the safety and environmental studies performed by the Fusion Safety Program for the Tokamak Physics Experiment and the Tokamak Fusion Test Reactor and of the technical support for commercial fusion facility conceptual design studies. A major activity this year has been work to develop a DOE Technical Standard for the safety of fusion test facilities

76 FR 61074 - USDA Increases the Fiscal Year 2011 Tariff-Rate Quota for Refined Sugar

Science.gov (United States)

2011-10-03

... Quota for Refined Sugar AGENCY: Office of the Secretary, USDA. ACTION: Notice. SUMMARY: The Secretary of Agriculture today announced an increase in the fiscal year (FY) 2011 refined sugar tariff-rate quota (TRQ) of... INFORMATION: A quantity of 22,000 MTRV for sugars, syrups, and molasses (collectively referred to as refined...

Annual report on the services for chemical analysis and scientific glassblowing in the fiscal year 2000

International Nuclear Information System (INIS)

Ito, Mitsuo; Obara, Kazuhiro; Toida, Yukio; Suzuki, Daisuke; Gunji, Katsubumi; Kato, Kaneharu; Watanabe, Kazuo

2002-01-01

A variety of analytical service and glassblowing service was carried out on requests from research laboratories and R and D programs within JAERI. In the field of analytical service, various samples such as nuclear fuels, nuclear materials and radioactive wastes, were analyzed using mainly Inductively Coupled Plasma Atomic Emission Spectrometry (ICP-AES), Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Thermal Ionization Mass Spectrometry (TIMS), Electron Probe X-ray Microanalyzer (EPMA), etc., and mostly in combination with various chemical separation methods. In the glassblowing service, various experimental instruments and vessels made of Pyrex glass or quartz glass were produced and repaired. Thirty-three requests for the analytical service and 132 requests for the glassblowing service have been received and treated in the fiscal year 2000. This report describes the activity of the analytical service and the glassblowing service performed in the fiscal year 2000. (author)

Fort Collins Science Center-Fiscal year 2009 science accomplishments

Science.gov (United States)

Wilson, Juliette T.

2010-01-01

Public land and natural resource managers in the United States are confronted with increasingly complex decisions that have important ramifications for both ecological and human systems. The scientists and technical professionals at the U.S. Geological Survey Fort Collins Science Center?many of whom are at the forefront of their fields?possess a unique blend of ecological, socioeconomic, and technological expertise. Because of this diverse talent, Fort Collins Science Center staff are able to apply a systems approach to investigating complicated ecological problems in a way that helps answer critical management questions. In addition, the Fort Collins Science Center has a long record of working closely with the academic community through cooperative agreements and other collaborations. The Fort Collins Science Center is deeply engaged with other U.S. Geological Survey science centers and partners throughout the Department of the Interior. As a regular practice, we incorporate the expertise of these partners in providing a full complement of ?the right people? to effectively tackle the multifaceted research problems of today's resource-management world. In Fiscal Year 2009, the Fort Collins Science Center's scientific and technical professionals continued research vital to Department of the Interior's science and management needs. Fort Collins Science Center work also supported the science needs of other Federal and State agencies as well as non-government organizations. Specifically, Fort Collins Science Center research and technical assistance focused on client and partner needs and goals in the areas of biological information management and delivery, enterprise information, fisheries and aquatic systems, invasive species, status and trends of biological resources (including human dimensions), terrestrial ecosystems, and wildlife resources. In the process, Fort Collins Science Center science addressed natural-science information needs identified in the U

An analytical model for the prediction of rip spacing in intermediate ...

Indian Academy of Sciences (India)

61

study, an analytical model was presented to predict the spacing of channel rip currents (Srip) ... beach and normal wave incidence in two cases with the fixed breaking line and variable one .... On the other hand, in the above relations radiation.

Mizunami Underground Research Project annual report in the 2002 fiscal year

International Nuclear Information System (INIS)

Ota, Kunio; Amano, Kenji; Kumazaki, Naoki

2003-07-01

The current geoscientific research of the Mizunami Underground Research Laboratory (MIU) Project have been carried out since the 1996 fiscal year at the Shobasama site in Akeyo-cho, Mizunami City, Gifu Prefecture. The main goals of the MIU Project are to establish appropriate methodologies for reliably investigating and assessing a deep subsurface, and to develop a range of engineering techniques for deep underground application in granite. This site for MIU construction was changed in January 2002, from the Shobasama site to city-owned land (MIU Construction Site) after lease contract with Mizunami city. The surface-based investigations at the MIU Construction site have started since February 2002. In 2002 fiscal year, geophysical survey and shallow borehole investigations were conducted and deep borehole investigations have started for modeling and characterization of geological environment in the MIU Construction Site before sinking the shafts. Detail of study and survey during the construction phase of MIU project was planned based on the layout and plan of construction of the underground facilities as one of the results of development of engineering technologies in a deep underground. In the Shobasama site, VSP survey was carried out to improve the model of geological environment. Hydrogeological model was calibrated using the results of long-term pumping test and long-term subsurface and groundwater monitoring. Important factors for hydrogeological modeling were evaluated as the results of numerical analysis by multiple approaches of groundwater flow modeling. The preliminary analysis based on the rock mechanical model at the Shobasama site was performed to estimate the deformation caused by excavation of the underground facilities. (author)

Advanced reactors transition fiscal year 1995 multi-year program plan WBS 7.3

International Nuclear Information System (INIS)

Loika, E.F.

1994-01-01

This document describes in detail the work to be accomplished in FY-1995 and the out years for the Advanced Reactors Transition (WBS 7.3). This document describes specific milestones and funding profiles. Based upon the Fiscal Year 1995 Multi-Year Program Plan, DOE will provide authorization to perform the work outlined in the FY 1995 MYPP. Following direction given by the US Department of Energy (DOE) on December 15, 1993, Advanced Reactors Transition (ART), previously known as Advanced Reactors, will provide the planning and perform the necessary activities for placing the Fast Flux Test Facility (FFTF) in a radiologically and industrially safe shutdown condition. The DOE goal is to accomplish the shutdown in approximately five years. The Advanced Reactors Transition Multi-Year Program Plan, and the supporting documents; i.e., the FFTF Shutdown Program Plan and the FFTF Shutdown Project Resource Loaded Schedule (RLS), are defined for the life of the Program. During the transition period to achieve the Shutdown end-state, the facilities and systems will continue to be maintained in a safe and environmentally sound condition. Additionally, facilities that were associated with the Office of Nuclear Energy (NE) Programs, and are no longer required to support the Liquid Metal Reactor Program will be deactivated and transferred to an alternate sponsor or the Decontamination and Decommissioning (D and D) Program for final disposition, as appropriate

Annual report of National Institute of Radiological Sciences of the fiscal year 1981

International Nuclear Information System (INIS)

1982-10-01

This report covers the period from April 1, 1981, to March 31, 1982, and the information on the research carried out by the staffs of the institute during this period is given. The total budget for the fiscal year 1981 was 5,038.9 million yen including personnel costs. Besides basic research, three long term projects have been carried on, i.e. the risk assessment on low level radiation, the research on the exposure to environmental radiation caused by nuclear facilities and others and the medical application of a particle accelerator. In connection with the project on the risk assessment of low level radiation, a new laboratory for the research on internal radiation effect has been under construction, and is expected to be completed in the fiscal year 1983. The biological effect of tritium has been adopted as a subtheme of this project. These three projects have progressed satisfactorily. In the report, the summaries of 10 papers on physics, 5 papers on chemistry, 9 papers on biochemistry and biophysics, 13 papers on cytology and morphology, 10 papers on physiology, 9 papers on genetics, 8 papers on immunology and hematology, 8 papers on medical studies and 17 papers on environmental studies are collected. (Kako, I.)

Annual report of National Institute of Radiological Sciences of the fiscal year 1985

International Nuclear Information System (INIS)

1986-05-01

The activities of National Institute of Radiological Sciences in fiscal year 1985 was carried out on the basis of the total budget of 5,550.597 million yen and 404 regular staffs. The ordinary research was carried out on 65 subjects, and the results of internationally high level were obtained. The special research was carried out by selecting four subjects: the biological effect of tritium accompanying fusion reactor development, the probabilistic effect of radiation and risk evaluation, the evaluation of exposure to environmental radiation, and the medical application of heavy particle beam. In addition to these, the specified research and the research based on the science and technology promotion coordination expense were carried out. In this institute, research has been advanced by collective discipline method, and the results have obtained high reputation. This fact owes much to the efforts of Administration Division, Technical Division and Hospital Division as well as Research Division. The total number of trainees who finished various courses reached 3651 in fiscal year 1985, and this has contributed largely to the protection from and the utilization of radiation in Japan. Recently, the importance of international exchange has increased, and efforts have been exerted to take part in various international activities overcoming all difficulties. (Kako, I.)

Office of Inspector General fiscal year 1996 annual work plan

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-10-01

This FY 1996 Office of Inspector General (OIG) Annual Work Plan is a summary and distillation of information contained in annual work plans, and includes audits and inspections that are carried over from FY 1995 as well as audits and inspections scheduled to start during FY 1996. Audits and inspections included in this consolidated OIG Annual Work Plan will be performed by OIG staff. Specialized expertise available through a Certified Public Accounting firm will be used to assist in auditing the Department`s financial statements. As part of the OIG Cooperative Audit Strategy, additional audit coverage of the Department`s programs is provided by internal auditors of the Department`s integrated contractors. Through the Cooperative Audit Strategy, the OIG ensures that the internal auditors satisfy audit standards, provides planning guidance to the internal auditors, coordinates work to avoid duplication, and tracks the work of internal auditors to ensure that needed audits are performed. Applicable portions of the four annual work plans issued for Fiscal Year 1996 by the Deputy/Assistant Inspectors General have been combined to form a major part of this overall OIG Annual Work Plan. Also included are portions of the most recent OIG Semiannual Reports to Congress to give an overview of the OIG`s mission/organization, resource status, and the environment in which the OIG currently operates. The OIG Annual Work Plan also lists ongoing and planned audits and inspections, and it presents investigative statistics which have been previously reported in the two OIG Semiannual Reports to Congress which cover Fiscal Year 1995. Furthermore, included in this work plan are descriptions of several innovations developed by the OIG to streamline its operations and to conserve as much efficiency and economy as possible in a time of resource reductions.

77 FR 45624 - Animal Drug User Fee Rates and Payment Procedures for Fiscal Year 2013

Science.gov (United States)

2012-08-01

.... currency by check, bank draft, or U.S. postal money order payable to the order of the Food and Drug... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0806] Animal Drug User Fee Rates and Payment Procedures for Fiscal Year 2013 AGENCY: Food and Drug...

3 CFR - Fiscal Year 2010 Refugee Admissions Numbers and Authorizations of In-country Refugee Status...

Science.gov (United States)

2010-01-01

... 3 The President 1 2010-01-01 2010-01-01 false Fiscal Year 2010 Refugee Admissions Numbers and Authorizations of In-country Refugee Status Pursuant to Sections 207 and 101(A)(42), Respectively, of the Immigration and Nationality Act, and Determination Pursuant to Section 2(B)(2) of the Migration and Refugee...

76 FR 26324 - Order Making Fiscal Year 2012 Annual Adjustments to Section 31 Fee Rates

Science.gov (United States)

2011-05-06

... of x. 3. Calculate the mean and standard deviation of the series {[Delta] 1 , [Delta] 2... 2012 Annual Adjustments to Section 31 Fee Rates I. Background Section 31 of the Securities Exchange Act... the fee rates under Sections 31(b) and (c) of the Exchange Act in fiscal years 2002 through 2011. II...

78 FR 691 - Maximum Loan Amount for Business and Industry Guaranteed Loans in Fiscal Year 2013

Science.gov (United States)

2013-01-04

... DEPARTMENT OF AGRICULTURE Rural Business-Cooperative Service Maximum Loan Amount for Business and Industry Guaranteed Loans in Fiscal Year 2013 AGENCY: Rural Business-Cooperative Service, USDA. ACTION... and Industry (B&I) guaranteed loans of $25 million or less under certain circumstances. Due to the...

Fiscal sustainability and fiscal policy targets

DEFF Research Database (Denmark)

Andersen, Torben M.

Analyses of fiscal sustainability have become integral parts of fiscal policy planning due to high debt levels and projected demographic changes. A popular metric by which to evaluate sustainability gaps is the so-called S2 metric given as the permanent change in the primary budget balance...... indicator can be given a normative interpretation, and this issue is extensively discussed. The paper ends by discussing the formulation of fiscal policy targets to ensure fiscal sustainability....... (relative to GDP) needed to meet the intertemporal budget constraint. While a very useful metric it also suffers from some problems, and the paper discusses some of the problems with this metric as a way to assess fiscal sustainability problems. A particular important issue is the extent to which the S2...

CONSTITUTIONAL ECONOMICS, FISCAL POLICY RULES, ANDTHECASE OF TURKEY

Directory of Open Access Journals (Sweden)

Osman Nuri ARAS

2011-07-01

Full Text Available Discretionary fiscal policies have arisen because of dominant Keynesianeconomic policies from 1930’s to 1970’s. Public expenditures intensively andexcessively increased in order to ensure macroeconomic stability during thisperiod. Many countries faced the emergence of macroeconomic problems such asaffectively using public resources, budget deficitand inflation. As a result,Keynesian economic policies and the stagnation experienced in following highinflation years have faced economies with stagflation process in the 1970’s.However, Keynesian approach did not solve the problem. Therefore, neweconomic approaches developed for solving the problem. One of the neweconomic approaches was Constitutional Economic Theory. The theory includeseconomic policy rules including fiscal rules as well as monetary rules.Fiscal rules have been one of the main stabilization tools in obtaining budget andpublic finance balance. Many countries have implemented specific fiscal policyrules to struggle with economic instabilities, budget deficits and public financialimbalances.A specific form of fiscal policy rule has been started to implement in Turkey since1999. Several fiscal policy rules have been adoptedin Turkey’s public financialmanagement system as part of the economic program which was conducted withthe collaboration of IMF since 1999. These rules are called as implicit fiscalpolicy rules. These fiscal rules have become a draft legal text in 2010 as “FiscalRule Draft Law”. Although the fiscal rule was planned to start the application period as of 2011, it is delayed to fiscal year 2012 because of some economicreasons

RIP Input Tables From WAPDEG for LA Design Selection: Continuous Pre-Closure Ventilation

International Nuclear Information System (INIS)

K.G. Mon

1999-01-01

The purpose of this calculation is to document the creation of .tables for input into Integrated Probabilistic Simulator for Environmental Systems (RIP) version 5.19.01 (Golder Associates 1998) from Waste Package Degradation (WAPDEG) version 3.09 (CRWMS M and O 1998b. ''Software Routine Report for WAPDEG'' (Version 3.09)) simulations. This calculation details the creation of the RIP input tables (representing waste package corrosion degradation over time) for the License Application Design Selection (LADS) analysis of the effects of continuous pre-closure ventilation. Ventilation during the operational phase of the repository could remove considerable water from the system, as well as reduce temperatures. Pre-closure ventilation is LADS Design Feature 7

An Analysis of the President’s Budgetary Proposals for Fiscal Year 2010

Science.gov (United States)

2009-06-01

C corporations are corporations that are subject to the corporate income tax . 20 AN ANALYSIS OF THE PRESIDENT’S BUDGETARY PROPOSALS FOR FISCAL YEAR...dividends lower the overall taxation of corporate profits, some of which are taxed twice: once under the corporate income tax , and again when people...earnings are not sub- ject to the corporate income tax , such as gains on real estate held by individuals. The lower capital gains tax rate also

Fiscal Federalism

DEFF Research Database (Denmark)

Feng, Xingyuan; Ljungwall, Christer; Guo, Sujian

2013-01-01

China's central–local relations have been marked by perpetual changes amidst economic restructuring. Fiscal decentralization on the expenditure side has been paralleled by centralization on the revenue side, accompanied by political centralization. Hence, our understanding of China's fiscal...... relations is not without controversy. This paper aims to make a theoretical contribution to the ongoing debate on ‘fiscal federalism’ by addressing crucial questions regarding China's central–local fiscal relations: first, to what extent do Chinese central–local fiscal relations conform to fiscal federalism...

Fiscal councils and economic volatility

Czech Academy of Sciences Publication Activity Database

Geršl, A.; Jašová, M.; Zápal, Jan

2014-01-01

Roč. 64, č. 3 (2014), s. 190-212 ISSN 0015-1920 Grant - others:UK(CZ) UNCE 204005/2012 Institutional support: PRVOUK-P23 Keywords : dynamic inconsistency * fiscal and monetary policy interaction * independent fiscal council Subject RIV: AH - Economic s Impact factor: 0.420, year: 2014 http://journal.fsv.cuni.cz/storage/1298_jasova.pdf

Report: Fiscal Year 2011 Federal Information Security Management Act Report Status of EPA’s Computer Security Program

Science.gov (United States)

Report #12-P-0062, November 9, 2011. Attached is the Office of Inspector General’s (OIG’s) Fiscal Year 2011 Federal Information Security Management Act (FISMA) Reporting Template, as prescribed by the Office of Management and Budget (OMB).

Federal Geothermal Research Program Update Fiscal Year 1998

Energy Technology Data Exchange (ETDEWEB)

Keller, J.G.

1999-05-01

This report reviews the specific objectives, status, and accomplishments of DOE's Geothermal Research Program for Fiscal Year 1998. The Exploration Technology research area focuses on developing instruments and techniques to discover hidden hydrothermal systems and to expose the deep portions of known systems. The Reservoir Technology research combines laboratory and analytical investigations with equipment development and field testing to establish practical tools for resource development and management for both hydrothermal and hot dry rock reservoirs. The Drilling Technology projects focus on developing improved, economic drilling and completion technology for geothermal wells. The Conversion Technology research focuses on reducing costs and improving binary conversion cycle efficiency, to permit greater use of the more abundant moderate-temperature geothermal resource, and on the development of materials that will improve the operating characteristics of many types of geothermal energy equipment. Direct use research covers the direct use of geothermal energy sources for applications in other than electrical production.

Fusion Safety Program annual report: Fiscal year 1986

International Nuclear Information System (INIS)

Holland, D.F.; Merrill, B.J.; Herring, J.S.; Piet, S.J.; Longhurst, G.R.

1987-06-01

This report summarizes the Fusion Safety Program's (FSP) major activities in fiscal year 1986. The Idaho National Engineering Laboratory (INEL) is the designated lead laboratory, and EG and G Idaho, Inc., is the prime contractor for FSP, which was initiated in 1979. Activities are conducted at the INEL and in participating facilities, including the Hanford Engineering Development Laboratory (HEDL), the Massachusetts Institute of Technology (MIT), and the University of Wisconsin. The technical areas covered in this report include tritium safety, activation product release, reactions involving lithium breeding materials, safety of fusion magnet systems, plasma disruption, risk assessment methodology, and computer code development for reactor transients. Contributions to the Technical Planning Activity (TPA) and the ''white paper'' study by the Environmental, Safety,and Economics Committee (ESECOM) are summarized. The report also includes a summary of the safety and environmental analysis and documentation performed by the INEL for the Compact Ignition Tokamak (CIT) design project

Development of heading/ripping systems and immediate roadway support (Report on ECSC contract 6220-62/8/801)

Energy Technology Data Exchange (ETDEWEB)

1977-01-01

The development of a combined heading and ripping system to enable the heading to be advanced while the coal and dirt were taken and discharged separately is discussed. A rotary head ripping machine fitted with cutting picks, dirt stowing machinery and ancillary equipment were developed. Work on the design and testing of powered roadway supports around roadheading machines showed that the problems arising may outweigh any of the possible advantages.

Revenues and Expenditures for Public Elementary and Secondary School Districts: School Year 2010-11 (Fiscal Year 2011). First Look (Provisional Data). NCES 2013-344

Science.gov (United States)

Cornman, Stephen Q.; Keaton, Patrick; Glander, Mark

2013-01-01

This report presents data from the School District Finance Survey (F-33) of the Common Core of Data (CCD) survey system for school year (SY) 2010-11, fiscal year 2011 (FY 11). The F-33 survey is a school district-level financial survey that consists of data submitted annually to the National Center for Education Statistics (NCES) and the…

Do Municipal Mergers Improve Fiscal Outcomes?

DEFF Research Database (Denmark)

Hansen, Sune Welling; Houlberg, Kurt; Holm Pedersen, Lene

2014-01-01

Improved fiscal management is a frequent justification for promoting boundary consolidations. However, whether or not this is actually the case is rarely placed under rigorous empirical scrutiny. Hence, this article investigates if fiscal outcomes are improved when municipalities are merged....... The basic argument is that the conceptualisation of fiscal management in political science is often too narrow as it focuses on the budget and pays hardly any attention to balances in the final accounts and debts – elements of management which are central to policy making. On this background, the causal...... relationship between municipal mergers and fiscal outcomes is analysed. Measured on the balance between revenues and expenses, liquid assets and debts, municipal mergers improve the fiscal outcomes of the municipalities in a five-year perspective, although the pre-reform effects tend to be negative...

Electric and Hybrid Vehicles Program 18th annual report to Congress for Fiscal Year 1994

Science.gov (United States)

1995-04-01

The Department remains focused on the technologies that are critical to making electric and hybrid vehicles commercially viable and competitive with current production gasoline-fueled vehicles in performance, reliability, and affordability. During Fiscal Year 1994, significant progress was made toward fulfilling the intent of Congress. The Department and the United States Advanced Battery Consortium (a partnership of the three major domestic automobile manufacturers) continued to work together and to focus the efforts of battery developers on the battery technologies that are most likely to be commercialized in the near term. Progress was made in industry cost-shared contracts toward demonstrating the technical feasibility of fuel cells for passenger bus and light duty vehicle applications. Two industry teams which will develop hybrid vehicle propulsion technologies have been selected through competitive procurement and have initiated work, in Fiscal Year 1994. In addition, technical studies and program planning continue, as required by the Energy Policy Act of 1992, to achieve the goals of reducing the transportation sector dependence on imported oil, reducing the level of environmentally harmful emissions, and enhancing industrial productivity and competitiveness.

Computable General Equilibrium Model Fiscal Year 2013 Capability Development Report - April 2014

Energy Technology Data Exchange (ETDEWEB)

Edwards, Brian Keith [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). National Infrastructure Simulation and Analysis Center (NISAC); Rivera, Michael K. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). National Infrastructure Simulation and Analysis Center (NISAC); Boero, Riccardo [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). National Infrastructure Simulation and Analysis Center (NISAC)

2014-04-01

This report documents progress made on continued developments of the National Infrastructure Simulation and Analysis Center (NISAC) Computable General Equilibrium Model (NCGEM), developed in fiscal year 2012. In fiscal year 2013, NISAC the treatment of the labor market and tests performed with the model to examine the properties of the solutions computed by the model. To examine these, developers conducted a series of 20 simulations for 20 U.S. States. Each of these simulations compared an economic baseline simulation with an alternative simulation that assumed a 20-percent reduction in overall factor productivity in the manufacturing industries of each State. Differences in the simulation results between the baseline and alternative simulations capture the economic impact of the reduction in factor productivity. While not every State is affected in precisely the same way, the reduction in manufacturing industry productivity negatively affects the manufacturing industries in each State to an extent proportional to the reduction in overall factor productivity. Moreover, overall economic activity decreases when manufacturing sector productivity is reduced. Developers ran two additional simulations: (1) a version of the model for the State of Michigan, with manufacturing divided into two sub-industries (automobile and other vehicle manufacturing as one sub-industry and the rest of manufacturing as the other subindustry); and (2) a version of the model for the United States, divided into 30 industries. NISAC conducted these simulations to illustrate the flexibility of industry definitions in NCGEM and to examine the simulation properties of in more detail.

78 FR 17939 - Announcement of Funding Awards; Capital Fund Safety and Security Grants; Fiscal Year 2012

Science.gov (United States)

2013-03-25

...; Capital Fund Safety and Security Grants; Fiscal Year 2012 AGENCY: Office of the Assistant Secretary for... availability of the Safety and Security funds with PIH Notice 2012-38 (Notice), which was issued September 7... Fund Safety and Security grant program. FOR FURTHER INFORMATION CONTACT: For questions concerning the...

78 FR 56728 - Announcement of Funding Awards; Capital Fund Safety and Security Grants; Fiscal Year 2013

Science.gov (United States)

2013-09-13

...; Capital Fund Safety and Security Grants; Fiscal Year 2013 AGENCY: Office of the Assistant Secretary for... availability of the Safety and Security funds with PIH Notice 2013-10 (Notice), which was issued May 3, 2013... Fund Safety and Security grant program. FOR FURTHER INFORMATION CONTACT: For questions concerning the...

77 FR 23492 - Announcement of Funding Awards; Capital Fund Safety and Security Grants; Fiscal Year 2011

Science.gov (United States)

2012-04-19

...; Capital Fund Safety and Security Grants; Fiscal Year 2011 AGENCY: Office of the Assistant Secretary for... notified of the availability of the Safety and Security funds with PIH Notice 2011-56 (Notice), which was... award recipients under the Capital Fund Safety and Security grant program. FOR FURTHER INFORMATION...

76 FR 36567 - Announcement of Funding Awards; Indian Community Development Block Grant Program; Fiscal Year 2010

Science.gov (United States)

2011-06-22

... Village of Selawik, 500,000 Housing Water and sewer services to eight homes. Honorable Clyde Ramoth Sr... the Fiscal Year 2010 (FY 2010) Notice of Funding Availability (NOFA) for the Indian Community... program provides grants to Indian Tribes and Alaska Native Villages to develop viable Indian and Alaska...

Accidents, troubles and others in nuclear fuel facilities in fiscal year 1988

International Nuclear Information System (INIS)

1990-01-01

The number of the accidents, troubles and others reported on the basis of the 'Law concerning the regulation of nuclear raw material substances, nuclear fuel substances and nuclear reactors' in fiscal year 1988 was one. On February 23, 1989, in the controlled area of the plutonium waste treatment development facilities in Tokai Works. Power Reactor and Nuclear Fuel Development Corp., when one worker entered from a corridor into the material store, he fell down by mistake and broke the left collarbone, which required the hospitalization for about one month. (K.I.)

RCRA and operational monitoring (ROM): Multi-year program plan and fiscal year 96 work plan. WBS 1.5.3, Revision 1

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-09-01

The RCRA & Operational Monitoring (ROM) Program Office manages the Hanford Site direct funded Resource Conservation and Recovery Act (RCRA) and Operational Monitoring under Work Breakdown Structure (WBS) 1.01.05.03. The ROM Program Office is included in Hanford Technical Services, a part of Projects & Site Services of Westinghouse Hanford Company (WHC). The 1996 Multi-Year Program Plan (MYPP) includes the Fiscal Year Work Plan (FYWP). The Multi-Year Program Plan takes its direction from the Westinghouse Planning Baseline Integration Organization. The MYPP provides both the near term, enhanced details and the long term, projected details for the Program Office to use as baseline Cost, Scope and Schedule. Change Control administered during the fiscal year is against the baseline provided by near term details of this document. The MYPP process has been developed by WHC to meet its internal planning and integration needs and complies with the requirements of the US Department of Energy, Richland Operations Office (RL) Long Range Planning Process Directive (RLID 5000.2). Westinghouse Hanford Company (WHC) has developed the multi-year planning process for programs to establish the technical, schedule and cost baselines for program and support activities under WHC`s scope of responsibility. The baseline information is developed by both WHC indirect funded support services organization, and direct funded programs in WHC. WHC Planning and Integration utilizes the information presented in the program specific MYPP and the Program Master Baseline Schedule (PMBS) to develop the Site-Wide Integrated Schedule.

RCRA and operational monitoring (ROM): Multi-year program plan and fiscal year 96 work plan. WBS 1.5.3, Revision 1

International Nuclear Information System (INIS)

1995-09-01

The RCRA ampersand Operational Monitoring (ROM) Program Office manages the Hanford Site direct funded Resource Conservation and Recovery Act (RCRA) and Operational Monitoring under Work Breakdown Structure (WBS) 1.01.05.03. The ROM Program Office is included in Hanford Technical Services, a part of Projects ampersand Site Services of Westinghouse Hanford Company (WHC). The 1996 Multi-Year Program Plan (MYPP) includes the Fiscal Year Work Plan (FYWP). The Multi-Year Program Plan takes its direction from the Westinghouse Planning Baseline Integration Organization. The MYPP provides both the near term, enhanced details and the long term, projected details for the Program Office to use as baseline Cost, Scope and Schedule. Change Control administered during the fiscal year is against the baseline provided by near term details of this document. The MYPP process has been developed by WHC to meet its internal planning and integration needs and complies with the requirements of the US Department of Energy, Richland Operations Office (RL) Long Range Planning Process Directive (RLID 5000.2). Westinghouse Hanford Company (WHC) has developed the multi-year planning process for programs to establish the technical, schedule and cost baselines for program and support activities under WHC's scope of responsibility. The baseline information is developed by both WHC indirect funded support services organization, and direct funded programs in WHC. WHC Planning and Integration utilizes the information presented in the program specific MYPP and the Program Master Baseline Schedule (PMBS) to develop the Site-Wide Integrated Schedule

Revenues and Expenditures for Public Elementary and Secondary School Districts: School Year 2011-12 (Fiscal Year 2012). First Look. NCES 2014-303

Science.gov (United States)

Cornman, Stephen Q.

2015-01-01

This First Look report presents data on public elementary and secondary education revenues and expenditures at the local education agency (LEA) or school district level for fiscal year (FY) 2012.1. Specifically, this report includes findings from the following types of school finance data: (1) Revenue and expenditure totals by state and the 100…

Revenues and Expenditures for Public Elementary and Secondary School Districts: School Year 2012-13 (Fiscal Year 2013). First Look. NCES 2015-303

Science.gov (United States)

Cornman, Stephen Q.

2016-01-01

This First Look report presents data on public elementary and secondary education revenues and expenditures at the local education agency (LEA) or school district level for fiscal year (FY) 2013. Specifically, this report includes findings from the following types of school finance data: (1) revenue and expenditure totals by state and the 100…

76 FR 15349 - Fiscal Year 2010 Cost of Outpatient Medical, Dental, and Cosmetic Surgery Services Furnished by...

Science.gov (United States)

2011-03-21

... OFFICE OF MANAGEMENT AND BUDGET Fiscal Year 2010 Cost of Outpatient Medical, Dental, and Cosmetic Surgery Services Furnished by Department of Defense Medical Treatment Facilities; Certain Rates Regarding... recovery from tortiously liable third persons for the cost of outpatient medical, dental and cosmetic...

Annual report of Power Reactor and Nuclear Fuel Development Corporation, fiscal year 1996

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-09-01

The experimental FBR `Joyo` has continued the irradiation operation at 100 MWt. After the 11th periodic inspection, the 30th cycle operation was carried out. The cumulative operation time as of the end of the fiscal year was 51,630 hours, and the cumulative heat output was about 4.2 billion kWh. The prototype FBR `Monju` has succeeded in electric power generation in August, 1995, but the sodium leak accident occurred in December, 1995. The elucidation of the cause of the sodium leak accident and the total inspection for the safety have been carried out. As for FBRs, the research and development of the reactor physics, the design of a large FBR, the equipment systems, the fuel and materials, the structures and the safety have been advanced. The ATR `Fugen` Power Station has continued the operation smoothly, and as of the end of the fiscal year, the total generated electric power was about 17.3 billion kWh, and the capacity factor was 66.3%. It boasts about the result of using MOX fuel. The exploration of uranium resources, the development of uranium conversion, uranium enrichment and plutonium fuel, the reprocessing of spent fuel, the development of environmental technology for radioactive waste, creative and innovative research and development, safety control and safety research and others are reported. (K.I.)

Carbon Dioxide Information Analysis Center and World Data Center - A for atmospheric trace gases. Fiscal year 1996, annual report

Energy Technology Data Exchange (ETDEWEB)

Cushman, R.M.; Boden, T.A.; Jones, S.B. [and others

1997-02-01

Fiscal year 1996 was especially productive for the Carbon Dioxide Information Analysis Center (CDIAC) at Oak Ridge National Laboratory (ORNL). This report describes publications and statistical data from the CDIAC.

Annual summary report on the surveillance and maintenance activities for the Oak Rige National Laboratory Environmental Restoration Program for fiscal year 1995

International Nuclear Information System (INIS)

1995-11-01

This Annual Summary Report on the Surveillance and Maintenance Activities for the Oak Ridge National Laboratory Environmental Restoration Program for Fiscal Year 1995 was prepared to communicate the accomplishments of the Program during fiscal year 1995. This work was performed under work breakdown structure element 1.4.12.6.1.14.20 (activity data sheet 3314, ''Remedial Action Surveillance and Maintenance''). Publication of this document meets the Life Cycle Baseline milestone date of November 30, 1995. This document provides the accomplishments for both the Remedial Action and Decontamination and Decommissioning Surveillance and Maintenance programs

Scale determinants of fiscal investment in geological exploration: evidence from China.

Science.gov (United States)

Lu, Linna; Lei, Yalin

2013-01-01

With the continued growth in demand for mineral resources and China's efforts in increasing investment in geological prospecting, fiscal investment in geological exploration becomes a research hotspot. This paper examines the yearly relationship among fiscal investment in geological exploration of the current term, that of the last term and prices of mining rights over the period 1999-2009. Hines and Catephores' investment acceleration model is applied to describe the scale determinants of fiscal investment in geological exploration which are value-added of mining rights, value of mining rights and fiscal investment in the last term. The results indicate that when value-added of mining rights, value of mining rights or fiscal investment in the last term moves at 1 unit, fiscal investment in the current term will move 0.381, 1.094 or 0.907 units respectively. In order to determine the scale of fiscal investment in geological exploration for the current year, the Chinese government should take fiscal investment in geological exploration for the last year and the capital stock of the previous investments into account. In practice, combination of government fiscal investment in geological exploration with its performance evaluation can create a virtuous circle of capital management mechanism.

Implementation and modification of a three-dimensional radiation stress formulation for surf zone and rip-current applications

Science.gov (United States)

Kumar, N.; Voulgaris, G.; Warner, John C.

2011-01-01

Regional Ocean Modeling System (ROMS v 3.0), a three-dimensional numerical ocean model, was previously enhanced for shallow water applications by including wave-induced radiation stress forcing provided through coupling to wave propagation models (SWAN, REF/DIF). This enhancement made it suitable for surf zone applications as demonstrated using examples of obliquely incident waves on a planar beach and rip current formation in longshore bar trough morphology (Haas and Warner, 2009). In this contribution, we present an update to the coupled model which implements a wave roller model and also a modified method of the radiation stress term based on Mellor (2008, 2011a,b,in press) that includes a vertical distribution which better simulates non-conservative (i.e., wave breaking) processes and appears to be more appropriate for sigma coordinates in very shallow waters where wave breaking conditions dominate. The improvements of the modified model are shown through simulations of several cases that include: (a) obliquely incident spectral waves on a planar beach; (b) obliquely incident spectral waves on a natural barred beach (DUCK'94 experiment); (c) alongshore variable offshore wave forcing on a planar beach; (d) alongshore varying bathymetry with constant offshore wave forcing; and (e) nearshore barred morphology with rip-channels. Quantitative and qualitative comparisons to previous analytical, numerical, laboratory studies and field measurements show that the modified model replicates surf zone recirculation patterns (onshore drift at the surface and undertow at the bottom) more accurately than previous formulations based on radiation stress (Haas and Warner, 2009). The results of the model and test cases are further explored for identifying the forces operating in rip current development and the potential implication for sediment transport and rip channel development. Also, model analysis showed that rip current strength is higher when waves approach at angles of 5

Identification of RIP1 as a critical mediator of Smac mimetic-mediated sensitization of glioblastoma cells for Drozitumab-induced apoptosis.

Science.gov (United States)

Cristofanon, S; Abhari, B A; Krueger, M; Tchoghandjian, A; Momma, S; Calaminus, C; Vucic, D; Pichler, B J; Fulda, S

2015-04-16

This study aims at evaluating the combination of the tumor-necrosis-factor-related apoptosis-inducing ligand (TRAIL)-receptor 2 (TRAIL-R2)-specific antibody Drozitumab and the Smac mimetic BV6 in preclinical glioblastoma models. To this end, the effect of BV6 and/or Drozitumab on apoptosis induction and signaling pathways was analyzed in glioblastoma cell lines, primary glioblastoma cultures and glioblastoma stem-like cells. Here, we report that BV6 and Drozitumab synergistically induce apoptosis and reduce colony formation in several glioblastoma cell lines (combination indextrigger the formation of a cytosolic receptor-interacting protein (RIP) 1/Fas-associated via death domain (FADD)/caspase-8-containing complex and subsequent activation of caspase-8 and -3. BV6- and Drozitumab-induced apoptosis is blocked by the caspase inhibitor zVAD.fmk, pointing to caspase-dependent apoptosis. RNA interference-mediated silencing of RIP1 almost completely abolishes the BV6-conferred sensitization to Drozitumab-induced apoptosis, indicating that the synergism critically depends on RIP1 expression. In contrast, both necrostatin-1, a RIP1 kinase inhibitor, and Enbrel, a TNFα-blocking antibody, do not interfere with BV6/Drozitumab-induced apoptosis, demonstrating that apoptosis occurs independently of RIP1 kinase activity or an autocrine TNFα loop. In conclusion, the rational combination of BV6 and Drozitumab presents a promising approach to trigger apoptosis in glioblastoma, which warrants further investigation.

Mizunami Underground Research Laboratory project. Annual report for fiscal year 2007

International Nuclear Information System (INIS)

Nishio, Kazuhisa; Matsuoka, Toshiyuki; Tsuruta, Tadahiko; Amano, Kenji; Ohyama, Takuya; Takeuchi, Ryuji; Saegusa, Hiromitsu; Hama, Katsuhiro; Mizuno, Takashi; Sai, Masataka; Hirano, Toru; Iyatomi, Yosuke; Shimada, Akiomi; Matsui, Hiroya; Ogata, Nobuhisa; Uchida, Masahiro; Sugihara, Kozo; Mikake, Shinichiro; Ikeda, Koki; Yamamoto, Masaru

2009-03-01

Japan Atomic Energy Agency (JAEA) at Tono Geoscience Center (TGC) is developing a geoscientific research project named Mizunami Underground Research Laboratory (MIU) Project in crystalline rock environment in order to establish scientific and technological basis for geological disposal of HLW. Geoscientific research at MIU is planned to be carried out in three phases over a period of 20 years; Surface-based Investigation Phase (Phase I), Construction Phase (Phase II) and Operation Phase (Phase III). Currently, the project is under the Construction Phase. This document presents the following results of the research and development performed in fiscal year 2007, as a part of the Construction Phase based on the MIU Master Plan updated in 2002, 1) Investigation at the MIU Construction Site and the Shobasama Site, 2) Construction at the MIU Construction Site, 3) Research Collaboration. (author)

Mizunami Underground Research Laboratory project. Annual report for fiscal year 2005

International Nuclear Information System (INIS)

Nishio, Kazuhisa; Matsuoka, Toshiyuki; Tsuruta, Tadahiko; Amano, Kenji; Ohyama, Takuya; Takeuchi, Ryuji; Saegusa, Hiromitsu; Hama, Katsuhiro; Mizuno, Takashi; Sai, Masataka; Iyatomi, Yosuke; Shimada, Akiomi; Ogata, Nobuhisa; Uchida, Masahiro; Sugihara, Kozo; Mikake, Shinichiro; Ikeda, Koki; Yamamoto, Masaru; Yoshida, Haruo; Nakama, Shigeo; Seno, Yasuhiro; Kuroda, Hidetaka; Semba, Takeshi

2009-03-01

Japan Atomic Energy Agency (JAEA) at Tono Geoscience Center (TGC) is developing a geoscientific research project named Mizunami Underground Research Laboratory (MIU) project in crystalline rock environment in order to establish scientific and technological basis for geological disposal of HLW. Geoscientific research at MIU is planned to be carried out in three phases over a period of 20 years; Surface-based Investigation Phase (Phase 1), Construction Phase (Phase 2) and Operation Phase (Phase 3). Currently, the project is under the Construction Phase. This document presents the following results of the research and development performed in 2005 fiscal year, as a part of the Construction Phase based on the MIU Master Plan updated in 2002, 1) Investigation at the MIU Construction Site and the Shobasama Site, 2) Construction at the MIU Construction Site, 3) Research Collaboration. (author)

Mizunami Underground Research Laboratory project. Annual report for fiscal year 2008

International Nuclear Information System (INIS)

Takeuchi, Shinji; Kunimaru, Takanori; Nishio, Kazuhisa; Tsuruta, Tadahiko; Matsuoka, Toshiyuki; Hayano, Akira; Takeuchi, Ryuji; Saegusa, Hiromitsu; Ohyama, Takuya; Mizuno, Takashi; Hirano, Toru; Ogata, Nobuhisa; Hama, Katsuhiro; Iyatomi, Yosuke; Shimada, Akiomi; Matsui, Hiroya; Ito, Hiroaki; Sugihara, Kozo; Mikake, Shinichiro; Ikeda, Koki; Yamamoto, Masaru

2010-07-01

Japan Atomic Energy Agency (JAEA) at Tono Geoscience Center (TGC) is developing a geoscientific research project named Mizunami Underground Research Laboratory (MIU) Project in crystalline rock environment in order to establish scientific and technological basis for geological disposal of HLW. Geoscientific research at MIU is planned to be carried out in three phases over a period of 20 years; Surface-based Investigation Phase (Phase 1), Construction Phase (Phase 2) and Operation Phase (Phase 3). Currently, the project is under the Construction Phase. This document presents the following results of the research and development performed in fiscal year 2008, as a part of the Construction Phase based on the MIU Master Plan updated in 2002, 1) Investigation at the MIU Construction Site and the Shobasama Site, 2) Construction at the MIU Construction Site, 3) Research Collaboration. (author)

76 FR 375 - Notice of Availability: Notice of Funding Availability (NOFA) for HUD's Fiscal Year (FY) 2010...

Science.gov (United States)

2011-01-04

... comprehensive projects that address the problems of concentrated rural housing distress and community poverty... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5415-N-35] Notice of Availability: Notice of Funding Availability (NOFA) for HUD's Fiscal Year (FY) 2010 Rural Innovation Fund Program...

77 FR 14600 - Public Availability of the Department of Veterans Affairs Fiscal Year (FY) 2011 Service Contract...

Science.gov (United States)

2012-03-12

... DEPARTMENT OF VETERANS AFFAIRS Public Availability of the Department of Veterans Affairs Fiscal Year (FY) 2011 Service Contract Inventory AGENCY: Department of Veterans Affairs. ACTION: Notice of... Affairs (VA) is publishing this notice to advise the public of the availability of the FY 2011 Service...

Environmental Education and Development Division (EM-522). Annual report, Fiscal year 1993

Energy Technology Data Exchange (ETDEWEB)

1993-12-31

The Environmental Education and Development Division (EM-522) is one of three divisions within the Office of Technology Integration and Environmental Education and Development (EM-52) in Environmental Restoration and Waste Management`s (EM`s) Office of Technology Development (EM-50). The primary design criterion for EM-522 education activities is directly related to meeting EM`s goal of environmental compliance on an accelerated basis and cleanup of the 1989 inventory of inactive sites and facilities by the year 2019. Therefore, EM-522`s efforts are directed specifically toward stimulating knowledge and capabilities to achieve the goals of EM while contributing to DOE`s overall goal of increasing scientific, mathematical, and technical literacy and competency. This report discusses fiscal year 1993 activities.

77 FR 64311 - Potential Market Impact of the Proposed Fiscal Year 2014 Annual Materials Plan; National Defense...

Science.gov (United States)

2012-10-19

... actually be associated with the two material research and development projects will depend on the market... Market Impact of the Proposed Fiscal Year 2014 Annual Materials Plan; National Defense Stockpile Market... Stockpile Market Impact Committee, co-chaired by the Departments of Commerce and State, is seeking public...

United States Department Of Energy Office Of Environmental Management Technology Development Report Fiscal Year 2010

International Nuclear Information System (INIS)

Bush, S.

2010-01-01

The mission of the Department of Energy's (DOE's) Office of Environmental Management (EM) is to clean up the environmental legacy of nuclear weapons research and production during the Cold War. That mission includes cleaning up nuclear waste, contaminated groundwater and soil, nuclear materials, and contaminated facilities covering two million acres of land in thirty-five states. EM's principal program goals include timely completion of tank waste treatment facilities, reduction of the life-cycle costs and acceleration of the cleanup of the Cold War legacy, and reduction of the EM footprint. The mission of the EM Technology Innovation and Development program is to transform science and innovation into practical solutions to achieve the EM mission. During fiscal year 2010 (October 2009-September 2010), EM focused upon accelerating environmental cleanup by expeditiously filling identified gaps in available knowledge and technology in the EM program areas. This report describes some of the approaches and transformational technologies in tank waste processing, groundwater and soil remediation, nuclear materials disposition, and facility deactivation and decommissioning developed during fiscal year 2010 that will enable EM to meet its most pressing program goals.

UNITED STATES DEPARTMENT OF ENERGY OFFICE OF ENVIRONMENTAL MANAGEMENT TECHNOLOGY DEVELOPMENT REPORT FISCAL YEAR 2010

Energy Technology Data Exchange (ETDEWEB)

Bush, S.

2010-10-22

The mission of the Department of Energy's (DOE's) Office of Environmental Management (EM) is to clean up the environmental legacy of nuclear weapons research and production during the Cold War. That mission includes cleaning up nuclear waste, contaminated groundwater and soil, nuclear materials, and contaminated facilities covering two million acres of land in thirty-five states. EM's principal program goals include timely completion of tank waste treatment facilities, reduction of the life-cycle costs and acceleration of the cleanup of the Cold War legacy, and reduction of the EM footprint. The mission of the EM Technology Innovation and Development program is to transform science and innovation into practical solutions to achieve the EM mission. During fiscal year 2010 (October 2009-September 2010), EM focused upon accelerating environmental cleanup by expeditiously filling identified gaps in available knowledge and technology in the EM program areas. This report describes some of the approaches and transformational technologies in tank waste processing, groundwater and soil remediation, nuclear materials disposition, and facility deactivation and decommissioning developed during fiscal year 2010 that will enable EM to meet its most pressing program goals.

Fiscal year 1997-1998 waste information requirements document

International Nuclear Information System (INIS)

Poppiti, J.A.

1997-01-01

The Waste Information Requirements Document describes the activities of the Tank Waste Remediation System (TWRS) Characterization Project that provide characterization information on Hanford Site waste tanks. The characterization information is required to perform operations and meet the commitments of TWRS end users. These commitments are derived from the Hanford Federal Facility Agreement and Consent Order, also known as the Tri-Party Agreement; the Recommendation 93-5 Implementation Plan to the Defense Nuclear Facilities Safety Board (DNFSB); and other directives as listed in Section 4.0. This Waste Information Requirement Document applies to Fiscal Years 1997 and 1998 activities. Its contents are based on the best information available in August 1997. The format and content are based on the directions of DOE-RL (Sieracki, 1997) and Fluor Daniel Hanford Incorporated (Umek, 1997). Activities, such as the revision of the Tank Characterization Technical Sampling Basis (Brown et al. 1997), the revision of the data quality objectives (DQOs), issue closures, discussions with Ecology, and management decisions may cause subsequent updates to the Waste Information Requirements Document

Fusion Safety Program annual report, Fiscal Year 1993

International Nuclear Information System (INIS)

Longhurst, G.R.; Cadwallader, L.C.; Dolan, T.J.; Herring, J.S.; McCarthy, K.A.; Merrill, B.J.; Motloch, C.G.; Petti, D.A.

1993-12-01

This report summarizes the major activities of the Fusion Safety Program in Fiscal Year 1993. The Idaho National Engineering Laboratory (INEL) has been designated by DOE as the lead laboratory for fusion safety, and EG ampersand G Idaho, Inc., is the prime contractor for INEL operations. The Fusion Safety Program was initiated in 1979. Activities are conducted at the INEL and in participating organizations, including universities and private companies. Technical areas covered in the report include tritium safety, beryllium safety, activation product release, reactions involving potential plasma-facing materials, safety of fusion magnet systems, plasma disruptions and edge physics modeling, risk assessment failure rates, computer codes for reactor transient analysis, and regulatory support. These areas include work completed in support of the International Thermonuclear Experimental Reactor (ITER). Also included in the report are summaries of the safety and environmental studies performed at the INEL for the Tokamak Physics Experiment and the Tokamak Fusion Test Reactor projects at the Princeton Plasma Physics Laboratory and a summary of the technical support for the ARIES/PULSAR commercial reactor design studies

Fusion Safety Program annual report, fiscal year 1992

International Nuclear Information System (INIS)

Holland, D.F.; Cadwallader, L.C.; Herring, J.S.; Longhurst, G.R.; McCarthy, K.A.; Merrill, B.J.; Piet, S.J.

1993-01-01

This report summarizes the major activities of the Fusion Safety Program in fiscal year 1992. The Idaho National Engineering Laboratory (INEL) is the designated lead laboratory and EG ampersand G Idaho, Inc. is the prime contractor for this program. The Fusion Safety Program was initiated in 1979. Activities are conducted at the INEL and in participating organizations including the Westinghouse Hanford Company at the Hanford Engineering Development Laboratory, the Massachusetts Institute of Technology, and the University of Wisconsin. The technical areas covered in the report include tritium safety, activation product release, reactions involving beryllium, reactions involving lithium breeding materials, safety of fusion magnet systems, plasma disruptions, risk assessment failure rate data base, and computer code development for reactor transients. Also included in the report is a summary of the safety and environmental studies performed by the INEL for the Tokamak Physics Experiments and the Tokamak Fusion Test Reactor, the safety analysis for the International Thermonuclear Experimental Reactor design, and the technical support for the ARIES commercial reactor design study