Sample records for ring system 19f

  1. Magnetic properties and hyperfine interactions in Cr8, Cr7Cd, and Cr7Ni molecular rings from 19F-NMR

    Bordonali, L.; Garlatti, E.; Casadei, C. M.; Furukawa, Y.; Lascialfari, A.; Carretta, S.; Troiani, F.; Timco, G.; Winpenny, R. E. P.; Borsa, F.


    A detailed experimental investigation of the 19F nuclear magnetic resonance is made on single crystals of the homometallic Cr8 antiferromagnetic molecular ring and heterometallic Cr7Cd and Cr7Ni rings in the low temperature ground state. Since the F- ion is located midway between neighboring magnetic metal ions in the ring, the 19F-NMR spectra yield information about the local electronic spin density and 19F hyperfine interactions. In Cr8, where the ground state is a singlet with total spin ST = 0, the 19F-NMR spectra at 1.7 K and low external magnetic field display a single narrow line, while when the magnetic field is increased towards the first level crossing field, satellite lines appear in the 19F-NMR spectrum, indicating a progressive increase in the Boltzmann population of the first excited state ST = 1. In the heterometallic rings, Cr7Cd and Cr7Ni, whose ground state is magnetic with ST = 3/2 and ST = 1/2, respectively, the 19F-NMR spectrum has a complicated structure which depends on the strength and orientation of the magnetic field, due to both isotropic and anisotropic transferred hyperfine interactions and classical dipolar interactions. From the 19F-NMR spectra in single crystals we estimated the transferred hyperfine constants for both the F--Ni2+ and the F--Cd2+ bonds. The values of the hyperfine constants compare well to the ones known for F--Ni2+ in KNiF3 and NiF2 and for F--Cr3+ in K2NaCrF6. The results are discussed in terms of hybridization of the 2s, 2p orbitals of the F- ion and the d orbitals of the magnetic ion. Finally, we discuss the implications of our results for the electron-spin decoherence.

  2. Largely Deformed Dinuclear System Formed in 19F +27A1 Dissipative Collision

    HAN Jian-Long; WU He-Yu; LI Zhi-Chang; LU Xiu-Qin; ZHAO Kui; ZHOU Ping; LIU Jian-Cheng; XU Guo-Ji; Sergey Yu Kun; WANG Qi; DONG Yu-Chuan; LI Song-Lin; DUAN Li-Min; XU Hu-Shan; XU Hua-Gen; CHEN Ruo-Fu; BAI Zhen


    @@ Excitation functions are measured for different charge products of the 19F+27 Al reaction in the laboratory energy range 110.25-118.75MeV in steps of 250keV at θlab = 57°, 31° and -29°. The coherence rotation angular velocities of the intermediate dinuclear systems formed in the reaction are extracted from the cross section energy autocorrelation functions. Compared the angular velocity extracted from the experimental data with the ones deduced from the sticking limit, it is indicated that a larger deformation of the intermediate dinuclear system exists.

  3. Rotation and Decay of the Dinuclear System Formed in Dissipative Reaction of 19F+27Al%19F+27Al耗散反应中双核系统的转动与衰变

    韩建龙; 白真; 李志常; 路秀琴; 赵葵; 周平; 刘建成; Sergey Yu Kun; 王琦; 董玉川; 李松林; 段利敏; 吴和宇; 徐华根; 陈若富; 徐瑚珊



  4. Rotation and Deformation of the Dinuclear System Formed in Dissipative Reaction of 19F+27Al%19F+27Al耗散反应中双核系统的转动与形变

    韩建龙; 王琦; 董玉川; 李松林; 段利敏; 吴和宇; 徐华根; 陈若富; 徐瑚珊; 白真; 李志常; 路秀琴; 赵葵; 周平; 刘建成; SergeyYuKun



  5. Certified Reference Material for Use in (1)H, (31)P, and (19)F Quantitative NMR, Ensuring Traceability to the International System of Units.

    Rigger, Romana; Rück, Alexander; Hellriegel, Christine; Sauermoser, Robert; Morf, Fabienne; Breitruck, KathrinBreitruck; Obkircher, Markus


    In recent years, quantitative NMR (qNMR) spectroscopy has become one of the most important tools for content determination of organic substances and quantitative evaluation of impurities. Using Certified Reference Materials (CRMs) as internal or external standards, the extensively used qNMR method can be applied for purity determination, including unbroken traceability to the International System of Units (SI). The implementation of qNMR toward new application fields, e.g., metabolomics, environmental analysis, and physiological pathway studies, brings along more complex molecules and systems, thus making use of 1H qNMR challenging. A smart workaround is possible by the use of other NMR active nuclei, namely 31P and 19F. This article presents the development of three classes of qNMR CRMs based on different NMR active nuclei (1H, 31P, and 19F), and the corresponding approaches to establish traceability to the SI through primary CRMs from the National Institute of Standards and Technology and the National Metrology Institute of Japan. These TraceCERT® qNMR CRMs are produced under ISO/IEC 17025 and ISO Guide 34 using high-performance qNMR.

  6. Neptune's ring system.

    Porco, C. C.; Nicholson, P. D.; Cuzzi, J. N.; Lissauer, J. J.; Esposito, L. W.

    The authors review the current state of knowledge regarding the structure, particle properties, kinematics, dynamics, origin, and evolution of the Neptune rings derived from Earth-based and Voyager data. Neptune has a diverse system of five continuous rings - 2 broad (Galle and Lassell) and 3 narrow (Adams, Le Verrier, and Arago) - plus a narrow discontinuous ring sharing the orbit of one of its ring-region satellites, Galatea. The outermost Adams ring contains the only arcs observed so far in Voyager images. The five arcs vary in angular extent from ≡1° to ≡10°, and exhibit internal azimuthal structure with typical spatial scales of ≡0.5°. All five lie within ≡40° of longitude. Dust is present throughout the Neptune system and measureable quantities of it were detected over Neptune's north pole. The Adams ring (including the arcs) and the Le Verrier ring contain a significant fraction of dust. The Neptune ring particles are probably red, and may consist of ice "dirtied" with silicates and/or some carbon-bearing material. A kinematic model for the arcs derived from Voyager data, the arcs' physical characteristics, and their orbital geometry and phasing are all roughly in accord with single-satellite arc shepherding by Galatea, though the presence of small kilometer-sized bodies embedded either within the arcs or placed at their Lagrange points may explain some inconsistencies with this model.

  7. Planetary ring systems

    Miner, Ellis D; Cuzzi, Jeffrey N


    This is the most comprehensive and up-to-date book on the topic of planetary rings systems yet written. The book is written in a style that is easily accessible to the interested non expert. Each chapter includes notes, references, figures and tables.


    Oji, L.; Diprete, D.; Click, D.


    The Savannah River National Laboratory (SRNL) was asked by Liquid Waste Operations to characterize Tank 19F closure samples. Tank 19F slurry samples analyzed included the liquid and solid fractions derived from the slurry materials along with the floor scrape bottom Tank 19F wet solids. These samples were taken from Tank 19F in April 2009 and made available to SRNL in the same month. Because of limited amounts of solids observed in Tank 19F samples, the samples from the north quadrants of the tank were combined into one Tank 19F North Hemisphere sample and similarly the south quadrant samples were combined into one Tank 19F South Hemisphere sample. These samples were delivered to the SRNL shielded cell. The Tank 19F samples were analyzed for radiological, chemical and elemental components. Where analytical methods yielded additional contaminants other than those requested by the customer, these results were also reported. The target detection limits for isotopes analyzed were based on detection values of 1E-04 {micro}Ci/g for most radionuclides and customer desired detection values of 1E-05 {micro}Ci/g for I-129, Pa-231, Np-237, and Ra-226. While many of the target detection limits, as specified in the technical task request and task technical and quality assurance plans were met for the species characterized for Tank 19F, some were not met. In a number of cases, the relatively high levels of radioactive species of the same element or a chemically similar element precluded the ability to measure some isotopes to low levels. SRNL, in conjunction with the plant customer, reviewed all these cases and determined that the impacts were negligible.

  9. Parity nonconservation in /sup 19/F nuclei

    Elsener, K.; Gruebler, W.; Koenig, V.; Schmelzbach, P.A.; Ulbricht, J.; Vuaridel, B.; Singy, D.; Forstner, C.; Zhang, W.Z.


    The parity nonconserving asymmetry A/sub ..gamma../ in the decay of polarized /sup 19/F/sup */(110 keV) nuclei has been measured. A value of A/sub ..gamma../=-(6.83 +- 2.11) x 10/sup -5/ (total error) was found. Systematic errors are extensively investigated and found to be small. The absolute normalization is given by the /sup 19/F/sup */ polarization, which is found to be rho/sub F/=-0.52 +- 0.08 in a separate experiment, using a calibrated Compton polarimeter. The new result A/sub ..gamma../(/sup 19/F) is compared to earlier experiments and recent theoretical calculations. From an analysis including /sup 18/F and /sup 21/Ne results, constraints on the weak meson-nucleon coupling constants f/sub ..pi../ and h/sub rho//sup 0/ are deduced. Agreement with calculations based on the standard electroweak theory and QCD is found.

  10. Burnside Rings of Fusion Systems

    Reeh, Sune Precht

    , and we produce a basis for the Burnside ring that shares properties with the transitive sets for a finite group. We construct a transfer map from the p-local Burnside ring of the underlying p-group S to the p-local Burnside ring of F. Using such transfer maps, we give a new explicit construction...... of Burnside rings given by multiplication with the characteristic idempotent, and we show that this map is the transfer map previously constructed. Applying these results, we show that for every saturated fusion system the ring generated by all (non-idempotent) characteristic elements in the p-local double...... of the characteristic idempotent of F { the unique idempotent in the p-local double Burnside ring of S satisfying properties of Linckelmann and Webb. We describe this idempotent both in terms of fixed points and as a linear combination of transitive bisets. Additionally, using fixed points we determine the map...

  11. 19F single-quantum and 19F-33S heteronuclear multiple-quantum coherence NMR of SF6 in thermotropic nematogens and in the gas phase.

    Tervonen, Henri; Saunavaara, Jani; Ingman, L Petri; Jokisaari, Jukka


    (19)F single-quantum (SQC) and (19)F-(33)S heteronuclear multiple-quantum coherence (HMQC) NMR spectroscopy of sulfur hexafluoride (SF(6)) dissolved in thermotropic liquid crystals (TLCs) were used to investigate the properties of TLCs. On one hand, environmental effects on the NMR parameters of SF(6), (19)F nuclear shielding, (19)F-(33)S spin-spin coupling, secondary isotope effects of sulfur on (19)F shielding, and the self-diffusion coefficient in the direction of the external magnetic field were studied as well. The temperature dependence of the (19)F shielding of SF(6) in TLCs was modeled with a function that takes into account the properties of both TLC and SF(6). It appears that the TLC environment deforms the electronic system of SF(6) so that the (19)F shielding tensor becomes slightly anisotropic, with the anisotropy being from -0.5 to -1.4 ppm, depending upon the TLC solvent. On the contrary, no sign of residual dipolar coupling between (19)F and (33)S was found, meaning that the so-called deformational effects, which arise from the interaction between vibrational and reorientational motions of the molecule, on the geometry of the molecule are insignificant. Diffusion activation energies, E(a), were determined from the temperature dependence of the self-diffusion coefficients. In each TLC, E(a) increases when moving from an isotropic phase to a nematic phase. The spin-spin coupling constant, J((19)F,(33)S), increases by ca. 10 Hz when moving from the gas phase to TLC solutions. The secondary isotope shifts of (19)F shielding are practically independent of TLC solvent and temperature. For the first time, (19)F-(33)S heteronuclear multiple-quantum NMR spectra were recorded for SF(6) in the gas phase and in a liquid-crystalline solution.

  12. Synthesis of 19F in Wolf-Rayet stars

    Meynet, G.; Arnould, M.


    Meynet & Arnould (1993) have suggested that Wolf-Rayet (WR) stars could significantly contaminate the Galaxy with \\chem{19}{F}. In their scenario, \\chem{19}{F} is synthesized at the beginning of the He-burning phase from the \\chem{14}{N} left over by the previous CNO-burning core, and is ejected in the interstellar medium when the star enters its WC phase. Recourse to CNO seeds makes the \\chem{19}{F} yields metallicity-dependent. These yields are calculated on grounds of detailed stellar evolutionary sequences for an extended range of initial masses (from 25 to 120 Msun) and metallicities (Z=0.008, 0.02 and 0.04). The adopted mass loss rate prescription enables to account for the observed variations of WR populations in different environments. The \\chem{19}{F} abundance in the WR winds of 60 M_sun model stars is found to be about 10 to 70 times higher than its initial value, depending on the metallicity. This prediction is used in conjunction with a very simple model for the chemical evolution of the Galaxy to predict that WR stars could be significant (dominant?) contributors to the solar system fluorine content. We also briefly discuss the implications of our model on the possible detection of fluorine at high redshift.

  13. Burnside Rings of Fusion Systems

    Reeh, Sune Precht

    of the characteristic idempotent of F { the unique idempotent in the p-local double Burnside ring of S satisfying properties of Linckelmann and Webb. We describe this idempotent both in terms of fixed points and as a linear combination of transitive bisets. Additionally, using fixed points we determine the map......In this thesis we study the interactions between saturated fusion systems and group actions of the underlying p-groups. For a saturated fusion system F on a finite p-group S we construct the Burnside ring of F in terms of the finite S-sets whose actions respect the structure of the fusion system......, and we produce a basis for the Burnside ring that shares properties with the transitive sets for a finite group. We construct a transfer map from the p-local Burnside ring of the underlying p-group S to the p-local Burnside ring of F. Using such transfer maps, we give a new explicit construction...

  14. (19)F Oximetry with semifluorinated alkanes.

    Kegel, Stefan; Chacon-Caldera, Jorge; Tsagogiorgas, Charalambos; Theisinger, Bastian; Glatting, Gerhard; Schad, Lothar R


    This work examines the variation of longitudinal relaxation rate R1(= 1/T1) of the (19)F-CF3-resonance of semifluorinated alkanes (SFAs) with oxygen tension (pO2), temperature (T) and pH in vitro. Contrary to their related perfluorocarbons (PFCs), SFA are amphiphilic and facilitate stable emulsions, a prerequisite for clinical use. A linear relationship between R1 and pO2 was confirmed for the observed SFAs at different temperatures. Using a standard saturation recovery sequence, T1 has been successfully measured using fluorine (19)F-MRI with a self-constructed birdcage resonator at 9.4 T. A calibration curve to calculate pO2 depending on T and R1 was found for each SFA used. In contrast to the commonly used PFC, SFAs are less sensitive to changes in pO2, but more sensitive to changes in temperature. The influence of pH to R1 was found to be negligible.

  15. Injectable hyaluronic acid hydrogel for 19F magnetic resonance imaging

    Yang, X.; Sun, Y.; Kootala, S.; Hilborn, J.; Heerschap, A.; Ossipov, D.


    We report on a 19F labeled injectable hyaluronic acid (HA) hydrogel that can be monitored by both 1H and 19F MR imaging. The HA based hydrogel formed via carbazone reaction can be obtained within a minute by simple mixing of HA-carbazate and HA-aldehyde derivatized polymers. 19F contrast agent was l

  16. Visualizing arthritic inflammation and therapeutic response by fluorine-19 magnetic resonance imaging (19F MRI

    Balducci Anthony


    Full Text Available Abstract Background Non-invasive imaging of inflammation to measure the progression of autoimmune diseases, such as rheumatoid arthritis (RA, and to monitor responses to therapy is critically needed. V-Sense, a perfluorocarbon (PFC contrast agent that preferentially labels inflammatory cells, which are then recruited out of systemic circulation to sites of inflammation, enables detection by 19F MRI. With no 19F background in the host, detection is highly-specific and can act as a proxy biomarker of the degree of inflammation present. Methods Collagen-induced arthritis in rats, a model with many similarities to human RA, was used to study the ability of the PFC contrast agent to reveal the accumulation of inflammation over time using 19F MRI. Disease progression in the rat hind limbs was monitored by caliper measurements and 19F MRI on days 15, 22 and 29, including the height of clinically symptomatic disease. Naïve rats served as controls. The capacity of the PFC contrast agent and 19F MRI to assess the effectiveness of therapy was studied in a cohort of rats administered oral prednisolone on days 14 to 28. Results Quantification of 19F signal measured by MRI in affected limbs was linearly correlated with disease severity. In animals with progressive disease, increases in 19F signal reflected the ongoing recruitment of inflammatory cells to the site, while no increase in 19F signal was observed in animals receiving treatment which resulted in clinical resolution of disease. Conclusion These results indicate that 19F MRI may be used to quantitatively and qualitatively evaluate longitudinal responses to a therapeutic regimen, while additionally revealing the recruitment of monocytic cells involved in the inflammatory process to the anatomical site. This study may support the use of 19F MRI to clinically quantify and monitor the severity of inflammation, and to assess the effectiveness of treatments in RA and other diseases with an inflammatory

  17. APS storage ring vacuum system

    Niemann, R.C.; Benaroya, R.; Choi, M.; Dortwegt, R.J.; Goeppner, G.A.; Gonczy, J.; Krieger, C.; Howell, J.; Nielsen, R.W.; Roop, B.; Wehrle, R.B.


    The Advanced Photon Source synchrotron radiation facility, under construction at the Argonne National Laboratory, incorporates a large ring for the storage of 7 GeV positrons for the generation of photon beams for the facility's experimental program. The Storage Ring's 1104 m circumference is divided into 40 functional sectors. The sectors include vacuum, beam transport, control, acceleration and insertion device components. The vacuum system, which is designed to operate at a pressure of 1 n Torr, consists of 240 connected sections, the majority of which are fabricated from an aluminum alloy extrusion. The sections are equipped with distributed NeG pumping, photon absorbers with lumped pumping, beam position monitors, vacuum diagnostics and valving. The details of the vacuum system design, selected results of the development program and general construction plans are presented. 11 refs., 6 figs., 3 tabs.

  18. Vies Moyennes Des Etats Excites Du 19F

    Belafrites, A; Benazzouz, C; Benammar, M A


    The determination of the mean lifetime of excited states has been undertaken by coulomb excitation that is a process of inelastic scattering in which the incident particle is charged and provokes an excitation of the target nucleus by mean of the electromagnetic fields during the passage of the projectile. The cross section of this inelastic scattering is proportional to the width of the isomeric state. The mean lifetime of excited states of the 19F are determined by comparing the experimental results of reactions 19F(alpha,alpha' gamma)19F and 19F(p, p' gamma)19F with the theoretical calculations achieved with the help of the multiple coulomb excitation program Coulex. These mean lifetimes are compared to those restraints by Ajzenberg - Selove [1] and Alder and al. [2].

  19. Inductive Rings and Systems of Diophantine Equations

    Rong Fang BIE; Shi Qiang WANG


    In this paper, by using model-theoretic methods, it is shown that some systems of unsolved cubic diophantine equations in number theory can have solutions in certain inductive extension rings of the ring I of rational integers. These inductive rings are not fields, and every element of them is a sum of 4 cubes and a sum of 3 squares. Also some of them satisfy the Goldbach conjecture and some others don't.

  20. Through-space (19)F-(19)F spin-spin coupling in ortho-fluoro Z-azobenzene.

    Rastogi, Shiva K; Rogers, Robert A; Shi, Justin; Brown, Christopher T; Salinas, Cindy; Martin, Katherine M; Armitage, Jacob; Dorsey, Christopher; Chun, Gao; Rinaldi, Peter; Brittain, William J


    We report through-space (TS) (19)F-(19)F coupling for ortho-fluoro-substituted Z-azobenzenes. The magnitude of the TS-coupling constant ((TS) JFF ) ranged from 2.2-5.9 Hz. Using empirical formulas reported in the literature, these coupling constants correspond to non-bonded F-F distances (dFF) of 3.0-3.5 Å. These non-bonded distances are significantly smaller than those determined by X-ray crystallography or density functional theory, which argues that simple models of (19)F-(19)F TS spin-spin coupling solely based dFF are not applicable. (1)H, (13)C and (19)F data are reported for both the E and Z isomers of ten fluorinated azobenzenes. Density functional theory [B3YLP/6-311++G(d,p)] was used to calculate (19) F chemical shifts, and the calculated values deviated 0.3-10.0 ppm compared with experimental values.

  1. Study of the Halogen Bonding between Pyridine and Perfluoroalkyl Iodide in Solution Phase Using the Combination of FTIR and 19F NMR

    Briauna Hawthorne


    Full Text Available Halogen bonding between pyridine and heptafluoro-2-iodopropane (iso-C3F7I/heptafluoro-1-iodopropane (1-C3F7I was studied using a combination of FTIR and 19F NMR. The ring breathing vibration of pyridine underwent a blue shift upon the formation of halogen bonds with both iso-C3F7I and 1-C3F7I. The magnitudes of the shifts and the equilibrium constants for the halogen-bonded complex formation were found to depend not only on the structure of the halocarbon, but also on the solvent. The halogen bond also affected the Cα-F (C-F bond on the center carbon bending and stretching vibrations in iso-C3F7I. These spectroscopic effects show some solvent dependence, but more importantly, they suggest the possibility of intermolecular halogen bonding among iso-C3F7I molecules. The systems were also examined by 19F NMR in various solvents (cyclohexane, hexane, chloroform, acetone, and acetonitrile. NMR dilution experiments support the existence of the intermolecular self-halogen bonding in both iso-C3F7I and 1-C3F7I. The binding constants for the pyridine/perfluoroalkyl iodide halogen bonding complexes formed in various solvents were obtained through NMR titration experiments. Quantum chemical calculations were used to support the FTIR and 19F NMR observations.

  2. {sup 19}F MRI oximetry: simulation of perfluorocarbon distribution impact

    Baete, S H; Vandecasteele, J; De Deene, Y, E-mail: [Department of Radiation Oncology and Experimental Cancer Research, Ghent University, De Pintelaan 185, 9000 Gent (Belgium)


    In {sup 19}F MRI oximetry, a method used to image tumour hypoxia, perfluorocarbons serve as oxygenation markers. The goal of this study is to evaluate the impact of perfluorocarbon distribution and concentration in {sup 19}F MRI oximetry through a computer simulation. The simulation studies the correspondence between {sup 19}F measured (pO{sup FNMR}{sub 2}) and actual tissue oxygen tension (pO{sub 2}) for several tissue perfluorocarbon distributions. For this, a Krogh tissue model is implemented which incorporates the presence of perfluorocarbons in blood and tissue. That is, in tissue the perfluorocarbons are distributed homogeneously according to Gaussian diffusion profiles, or the perfluorocarbons are concentrated in the capillary wall. Using these distributions, the oxygen tension in the simulation volume is calculated. The simulated mean oxygen tension is then compared with pO{sup FNMR}{sub 2}, the {sup 19}F MRI-based measure of pO{sub 2} and with pO{sup 0}{sub 2}, pO{sub 2} in the absence of perfluorocarbons. The agreement between pO{sup FNMR}{sub 2} and actual pO{sub 2} is influenced by vascular density and perfluorocarbon distribution. The presence of perfluorocarbons generally gives rise to a pO{sub 2} increase in tissue. This effect is enhanced when perfluorocarbons are also present in blood. Only the homogeneous perfluorocarbon distribution in tissue with no perfluorocarbons in blood guarantees small deviations of pO{sup FNMR}{sub 2} from pO{sub 2}. Hence, perfluorocarbon distribution in tissue and blood has a serious impact on the reliability of {sup 19}F MRI-based measures of oxygen tension. In addition, the presence of perfluorocarbons influences the actual oxygen tension. This finding may be of great importance for further development of {sup 19}F MRI oximetry.

  3. 19F MRI oximetry: simulation of perfluorocarbon distribution impact

    Baete, S. H.; Vandecasteele, J.; De Deene, Y.


    In 19F MRI oximetry, a method used to image tumour hypoxia, perfluorocarbons serve as oxygenation markers. The goal of this study is to evaluate the impact of perfluorocarbon distribution and concentration in 19F MRI oximetry through a computer simulation. The simulation studies the correspondence between 19F measured (pOFNMR2) and actual tissue oxygen tension (pO2) for several tissue perfluorocarbon distributions. For this, a Krogh tissue model is implemented which incorporates the presence of perfluorocarbons in blood and tissue. That is, in tissue the perfluorocarbons are distributed homogeneously according to Gaussian diffusion profiles, or the perfluorocarbons are concentrated in the capillary wall. Using these distributions, the oxygen tension in the simulation volume is calculated. The simulated mean oxygen tension is then compared with pOFNMR2, the 19F MRI-based measure of pO2 and with pO02, pO2 in the absence of perfluorocarbons. The agreement between pOFNMR2 and actual pO2 is influenced by vascular density and perfluorocarbon distribution. The presence of perfluorocarbons generally gives rise to a pO2 increase in tissue. This effect is enhanced when perfluorocarbons are also present in blood. Only the homogeneous perfluorocarbon distribution in tissue with no perfluorocarbons in blood guarantees small deviations of pOFNMR2 from pO2. Hence, perfluorocarbon distribution in tissue and blood has a serious impact on the reliability of 19F MRI-based measures of oxygen tension. In addition, the presence of perfluorocarbons influences the actual oxygen tension. This finding may be of great importance for further development of 19F MRI oximetry.

  4. Lectures on algebraic system theory: Linear systems over rings

    Kamen, E. W.


    The presentation centers on four classes of systems that can be treated as linear systems over a ring. These are: (1) discrete-time systems over a ring of scalars such as the integers; (2) continuous-time systems containing time delays; (3) large-scale discrete-time systems; and (4) time-varying discrete-time systems.

  5. Centaur's ring system formation by close encounters

    De Santana, Thamiris; Winter, Othon


    Rupture of small bodies due to close approach to a massive body is a frequent event in the Solar System. Some of these small bodies can just disintegrate completely or suffer a material loss.In this work we study the gravitational interaction between a giant planet and a small body in close encounters in order to simulate the formation of a planetary ring system around a centaur by the partial rupture of the small body.Considering the current Chariklo's body and a disk of particles around it, we simulated the system under close encounters with one of giant planets.Another motivation for the study is also the centaur Chiron, that is a candidate to have a ring system like Chariklo. The characteristics of the encounters are defined by the impact parameter and the velocity at infinity.The results are presented in terms of conditions that could lead to a rupture that could generate a ring like system.

  6. Synthesis of $^{19}F$ in Wolf-Rayet stars

    Meynet, G


    Meynet and Arnould (1993) have suggested that Wolf-Rayet (WR) stars could significantly contaminate the Galaxy with 19F. In their scenario, 19F is synthesized at the beginning of the He-burning phase from the 14N left over by the previous CNO-burning core, and is ejected in the interstellar medium when the star enters its WC phase. Recourse to CNO seeds makes the 19F yields metallicity-dependent. These yields are calculated on grounds of detailed stellar evolutionary sequences for an extended range of initial masses (from 25 to 120 Msol) and metallicities (Z = 0.008, 0.02 and 0.04). The adopted mass loss rate prescription enables to account for the observed variations of WR populations in different environments. The 19F abundance in the WR winds of 60 Msol model stars is found to be about 10 to 70 times higher than its initial value, depending on the metallicity. This prediction is used in conjunction with a very simple model for the chemical evolution of the Galaxy to predict that WR stars could be significa...

  7. (19)F MRI for quantitative in vivo cell tracking.

    Srinivas, M.; Heerschap, A.; Ahrens, E.T.; Figdor, C.G.; Vries, I.J.M. de


    Cellular therapy, including stem cell transplants and dendritic cell vaccines, is typically monitored for dosage optimization, accurate delivery, and localization using noninvasive imaging, of which magnetic resonance imaging (MRI) is a key modality. (19)F MRI retains the advantages of MRI as an ima

  8. Clonal distribution of pneumococcal serotype 19F isolates from Ghana.

    Sparding, Nadja; Dayie, Nicholas T K D; Mills, Richael O; Newman, Mercy J; Dalsgaard, Anders; Frimodt-Møller, Niels; Slotved, Hans-Christian


    Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide. Pneumococcal strains are classified according to their capsular polysaccharide and more than 90 different serotypes are currently known. In this project, three distinct groups of pneumococcal carriage isolates from Ghana were investigated; isolates from healthy children in Tamale and isolates from both healthy and children attending the outpatient department at a hospital in Accra. The isolates were previously identified and characterized by Gram staining, serotyping and susceptibility to penicillin. In this study, isolates of the common serotype 19F were further investigated by Multi-Locus Sequence Typing (MLST). Overall, 14 different Sequence Types (STs) were identified by MLST, of which nine were novel based on the international MLST database. Two clones within serotype 19F seem to circulate in Ghana, a known ST (ST 4194) and a novel ST (ST 9090). ST 9090 was only found in healthy children in Accra, whereas ST 4194 was found equally in all children studied. In the MLST database, other isolates of ST 4194 were also associated with serotype 19F, and these isolates came from other West African countries. The majority of isolates were penicillin intermediate resistant. In conclusion, two clones within serotype 19F were found to be dominating in pneumococcal carriage in Accra and Tamale in Ghana. Furthermore, it seems as though the clonal distribution of serotype 19F may be different from what is currently known in Ghana in that many new clones were identified. This supports the importance of continued monitoring of pneumococcal carriage in Ghana and elsewhere when vaccines, e.g., PCV-13, have been introduced to monitor the possible future spread of antimicrobial resistant clones.

  9. Cell Labeling for 19F MRI: New and Improved Approach to Perfluorocarbon Nanoemulsion Design

    Jonathan Williams


    Full Text Available This report describes novel perfluorocarbon (PFC nanoemulsions designed to improve ex vivo cell labeling for 19F magnetic resonance imaging (MRI. 19F MRI is a powerful non-invasive technique for monitoring cells of the immune system in vivo, where cells are labeled ex vivo with PFC nanoemulsions in cell culture. The quality of 19F MRI is directly affected by the quality of ex vivo PFC cell labeling. When co-cultured with cells for longer periods of time, nanoemulsions tend to settle due to high specific weight of PFC oils (1.5–2.0 g/mL. This in turn can decrease efficacy of excess nanoemulsion removal and reliability of the cell labeling in vitro. To solve this problem, novel PFC nanoemulsions are reported which demonstrate lack of sedimentation and high stability under cell labeling conditions. They are monodisperse, have small droplet size (~130 nm and low polydispersity (<0.15, show a single peak in the 19F nuclear magnetic resonance spectrum at −71.4 ppm and possess high fluorine content. The droplet size and polydispersity remained unchanged after 160 days of follow up at three temperatures (4, 25 and 37 °C. Further, stressors such as elevated temperature in the presence of cells, and centrifugation, did not affect the nanoemulsion droplet size and polydispersity. Detailed synthetic methodology and in vitro testing for these new PFC nanoemulsions is presented.

  10. Control System of the Small Isochronous ring

    Felix Marti; Eduard Pozdeyev


    The purpose of this paper is to describe the control system of the Small Isochronous Ring (SIR) developed and built at the National Superconducting Cyclotron Laboratory (NSCL) at Michigan State University (MSU). SIR is a small-scale experiment that simulates the dynamics of intense beams in large accelerators. A 20 to 30 keV hydrogen or deuterium ion bunch is injected in the ring, extracted after a variable number of turns and its longitudinal profile is studied. Information about the electronics used and software written to control different injection line, ring and extraction line elements is included. Some of these elements are magnets, electrostatic quadrupoles, electric and magnetic correctors, scanning wires, emittance measurement system, chopper and a fast Faraday cup.

  11. Clonal distribution of pneumococcal serotype 19F isolates from Ghana

    Sparding, Nadja; Dayie, Nicholas Tete Kwaku Dzifa; Mills, Richael O.


    Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide. Pneumococcal strains are classified according to their capsular polysaccharide and more than 90 different serotypes are currently known. In this project, three distinct groups of pneumococcal carriage isolates from...... Ghana were investigated; isolates from healthy children in Tamale and isolates from both healthy and children attending the outpatient department at a hospital in Accra. The isolates were previously identified and characterized by Gram staining, serotyping and susceptibility to penicillin. In this study....... The majority of isolates were penicillin intermediate resistant. In conclusion, two clones within serotype 19F were found to be dominating in pneumococcal carriage in Accra and Tamale in Ghana. Furthermore, it seems as though the clonal distribution of serotype 19F may be different from what is currently known...

  12. Synthesis of fluorinated maltose derivatives for monitoring protein interaction by 19F NMR

    Michaela Braitsch


    Full Text Available A novel reporter system, which is applicable to the 19F NMR investigation of protein interactions, is presented. This approach uses 2-F-labeled maltose as a spy ligand to indirectly probe protein–ligand or protein–protein interactions of proteins fused or tagged to the maltose-binding protein (MBP. The key feature is the simultaneous NMR observation of both 19F NMR signals of gluco/manno-type-2-F-maltose-isomers; one isomer (α-gluco-type binds to MBP and senses the protein interaction, and the nonbinding isomers (β-gluco- and/or α/β-manno-type are utilized as internal references. Moreover, this reporter system was used for relative affinity studies of fluorinated and nonfluorinated carbohydrates to the maltose-binding protein, which were found to be in perfect agreement with published X-ray data. The results of the NMR competition experiments together with the established correlation between 19F chemical shift data and molecular interaction patterns, suggest valuable applications for studies of protein–ligand interaction interfaces.

  13. A Summary and Status of the SNS Ring Vacuum Systems

    Mapes, Michael; Hseuh Hsiao Chaun; Ladd, Peter; Rank, Jim; Smart, Loralie; Todd, Robert J; Weiss, Daniel


    The Spallation Neutron Source (SNS) ring is designed to accumulate high intensity protons. The SNS ring vacuum system consists of the High Energy Beam Transport (HEBT) line, Accumulator Ring and the Ring to Target Beam Transport (RTBT) line. The Accumulator ring has a circumference of 248m with 4 arcs and 4 straight sections, while the RTBT and HEBT have a total length of 350m of beam transport line. Ultrahigh vacuum of 10-9

  14. Chariklo's ring system 1. Structure of the ring system from stellar occultations

    Berard, Diane; Sicardy, Bruno; Braga-Ribas, Felipe; camargo, julio; Vieira-Martins, Roberto; Assafin, Marcelo; Sickafoose, Amanda A.; Colas, François; Dauvergne, Jean-Luc; Bath, Karl-Ludwig; Maquet, Lucie; Tancredi, Gonzalo; Richichi, Andrea; Puji, Irawati; Ivanov, Valentin; Bradshaw, Jonathan; Broughton, John; Meza, Erick; Ortiz, Jose-Luis; Duffard, Rene; Leiva, Rodrigo


    Two dense and narrow rings around Chariklo (the largest centaur object known to date) were discovered by stellar occultation on June 3, 2013 (Braga-Ribas et al., Nature 508, 72, 2014). The main and larger ring is called C1R, while the faintest one is called C2R.Here we report six others occultations by Chariklo's ring system observed on February 16, March 16, April 29, June 28, 2014 and April 26, May 12, 2015. They provide a total of fifteen ring profiles, among which are four resolved profiles of C1R.The latter exhibits a W-shape profile that is essentially opaque at the edges. Its width varies from 4.8 to 7.7 km over the available longitude range. Those caracteristics have been detected in Uranus elliptic rings. The equivalent width We (normal opacity x physical radial width) of C1R is 2 km with typical rms of 1 km, while C2R has We of 0.2 km (rms ~ 0.1 km). None of the rings exhibits variation of We with longitude.Assuming the rings are circular, we can exhibit a pole which is compatible with the two multi-chord ring detections (June 3, 2013 and April 29, 2014): αp=151.4° and δp=41.5°. We will then estimate an upper limit of a possible ring eccentricity based on those two observations.Part of the research leading to these results has received funding from the European Research Council under the European Community's H2020 (2014-2020/ ERC Grant Agreement n 669416 "LUCKY STAR").

  15. Imaging of intratumoral inflammation during oncolytic virotherapy of tumors by 19F-magnetic resonance imaging (MRI.

    Stephanie Weibel

    Full Text Available BACKGROUND: Oncolytic virotherapy of tumors is an up-coming, promising therapeutic modality of cancer therapy. Unfortunately, non-invasive techniques to evaluate the inflammatory host response to treatment are rare. Here, we evaluate (19F magnetic resonance imaging (MRI which enables the non-invasive visualization of inflammatory processes in pathological conditions by the use of perfluorocarbon nanoemulsions (PFC for monitoring of oncolytic virotherapy. METHODOLOGY/PRINCIPAL FINDINGS: The Vaccinia virus strain GLV-1h68 was used as an oncolytic agent for the treatment of different tumor models. Systemic application of PFC emulsions followed by (1H/(19F MRI of mock-infected and GLV-1h68-infected tumor-bearing mice revealed a significant accumulation of the (19F signal in the tumor rim of virus-treated mice. Histological examination of tumors confirmed a similar spatial distribution of the (19F signal hot spots and CD68(+-macrophages. Thereby, the CD68(+-macrophages encapsulate the GFP-positive viral infection foci. In multiple tumor models, we specifically visualized early inflammatory cell recruitment in Vaccinia virus colonized tumors. Furthermore, we documented that the (19F signal correlated with the extent of viral spreading within tumors. CONCLUSIONS/SIGNIFICANCE: These results suggest (19F MRI as a non-invasive methodology to document the tumor-associated host immune response as well as the extent of intratumoral viral replication. Thus, (19F MRI represents a new platform to non-invasively investigate the role of the host immune response for therapeutic outcome of oncolytic virotherapy and individual patient response.

  16. 19F-{ 1H} Nuclear Overhauser Effect and Proton Decoupling of 5-Fluorouracil and α-Fluoro-β-Alanine

    Krems, B.; Bachert, P.; Zabel, H. J.; Lorenz, W. J.

    19F-{ 1H} magnetic double-resonance experiments were performed on model solutions of the antitumor drug 5-fluorouracil (5-FU) and of α-fluoro-β-alanine (FBAL) in order to improve 19F NMR sensitivity for the application in pharmacokinetic studies in vivo. Upon driving the proton spins into saturation, a fluorine signal enhancement (nuclear Overhauser effect) was observed on the order of the theoretical NOE maximum γ H/2γ F, = 53% for purely dipolar coupled 19F- 1H spin systems in extreme narrowing. The dependence of the effect on proton excitation frequency and temporal parameters was measured and cross-relaxation rate constants of 0.07 s -1 (5-FU) and 0.19 s -1 (FBAL) were determined. Irradiation of the proton spin system by a broad pulse during the 19F signal detection period removed FBAL multiplet splittings completely and narrowed the linewidth of this resonance band by a factor of six, Application of proton presaturation in the 19F NMR examination of a patient undergoing 5-FU chemotherapy enhanced the signal-to-noise ratio of the major 5-FU catabolite FBAL detected noninvasively in the liver.

  17. Application of 19F MRI for in vivo detection of biological processes

    Basse-Lüsebrink, Thomas Christian


    This thesis focuses on various aspects and techniques of 19F magnetic resonance (MR). The first chapters provide an overview of the basic physical properties, 19F MR and MR sequences related to this work. Chapter 5 focuses on the application of 19F MR to visualize biological processes in vivo using two different animal models. The dissimilar models underlined the wide applicability of 19F MR in preclinical research. A subsection of Chapter 6 shows the application of compressed sensing (CS) to...


    Harris, S.


    Representative sampling has been completed for characterization of the residual material on the floor of Tank 19F as per the statistical sampling plan developed by Harris and Shine. Samples from eight locations have been obtained from the tank floor and two of the samples were archived as a contingency. Six samples, referred to in this report as the current scrape samples, have been submitted to and analyzed by SRNL. This report contains the statistical analysis of the floor sample analytical results to determine if further data are needed to reduce uncertainty. Included are comparisons with the prior Mantis samples results to determine if they can be pooled with the current scrape samples to estimate the upper 95% confidence limits (UCL95%) for concentration. Statistical analysis revealed that the Mantis and current scrape sample results are not compatible. Therefore, the Mantis sample results were not used to support the quantification of analytes in the residual material. Significant spatial variability among the current scrape sample results was not found. Constituent concentrations were similar between the North and South hemispheres as well as between the inner and outer regions of the tank floor. The current scrape sample results from all six samples fall within their 3-sigma limits. In view of the results from numerous statistical tests, the data were pooled from all six current scrape samples. As such, an adequate sample size was provided for quantification of the residual material on the floor of Tank 19F. The uncertainty is quantified in this report by an UCL95% on each analyte concentration. The uncertainty in analyte concentration was calculated as a function of the number of samples, the average, and the standard deviation of the analytical results. The UCL95% was based entirely on the six current scrape sample results (each averaged across three analytical determinations).

  19. Solid-state (19)F-NMR of peptides in native membranes.

    Koch, Katja; Afonin, Sergii; Ieronimo, Marco; Berditsch, Marina; Ulrich, Anne S


    To understand how membrane-active peptides (MAPs) function in vivo, it is essential to obtain structural information about them in their membrane-bound state. Most biophysical approaches rely on the use of bilayers prepared from synthetic phospholipids, i.e. artificial model membranes. A particularly successful structural method is solid-state NMR, which makes use of macroscopically oriented lipid bilayers to study selectively isotope-labelled peptides. Native biomembranes, however, have a far more complex lipid composition and a significant non-lipidic content (protein and carbohydrate). Model membranes, therefore, are not really adequate to address questions concerning for example the selectivity of these membranolytic peptides against prokaryotic vs eukaryotic cells, their varying activities against different bacterial strains, or other related biological issues.Here, we discuss a solid-state (19)F-NMR approach that has been developed for structural studies of MAPs in lipid bilayers, and how this can be translated to measurements in native biomembranes. We review the essentials of the methodology and discuss key objectives in the practice of (19)F-labelling of peptides. Furthermore, the preparation of macroscopically oriented biomembranes on solid supports is discussed in the context of other membrane models. Two native biomembrane systems are presented as examples: human erythrocyte ghosts as representatives of eukaryotic cell membranes, and protoplasts from Micrococcus luteus as membranes from Gram-positive bacteria. Based on our latest experimental experience with the antimicrobial peptide gramicidin S, the benefits and some implicit drawbacks of using such supported native membranes in solid-state (19)F-NMR analysis are discussed.


    Stefanko, D.; Langton, C.


    performance properties; (3) Design up to 2 additional grout systems for filling the Tank 18-F and Tank 19-F equipment; (4) Prepare samples of candidate grouts and measure fresh properties, thermal properties and cured properties; (5) Recommend a grout for the Tier 1A equipment fill mock up - ADMP 4 foot high mock up, 1 inch and 2 inch pipes; (6) Support procurement of materials for the Tier 1A equipment fill mock up test; (7) Prepare samples of the recommended grout for hydraulic property measurements which can be used for comparison to values used in the F- Tank Farm Performance Assessment (PA); and (8) Document equipment fill grout data and recommendations in a report.

  1. Fluorinated Carbohydrates as Lectin Ligands: 19F-Based Direct STD Monitoring for Detection of Anomeric Selectivity

    Ribeiro, João P.; Diercks, Tammo; Jiménez-Barbero, Jesús; André, Sabine; Gabius, Hans-Joachim; Cañada, Francisco Javier


    The characterization of the binding of reducing carbohydrates present as mixtures of anomers in solution to a sugar recepor (lectin) poses severe difficulties. In this situation, NMR spectroscopy enables the observation of signals for each anomer in the mixture by applying approaches based on ligand observation. Saturation transfer difference (STD) NMR allows fast and efficient screening of compound mixtures for reactivity to a receptor. Owing to the exceptionally favorable properties of 19F in NMR spectroscopy and the often complex 1H spectra of carbohydrates, 19F-containing sugars have the potential to be turned into versatile sensors for recognition. Extending the recently established 1H → 1H STDre19F-NMR technique, we here demonstrate its applicability to measure anomeric selectivity of binding in a model system using the plant lectin concanavalin A (ConA) and 2-deoxy-2-fluoro-d-mannose. Indeed, it is also possible to account for the mutual inhibition between the anomers on binding to the lectin by means of a kinetic model. The monitoring of 19F-NMR signal perturbation disclosed the relative activities of the anomers in solution and thus enabled the calculation of their binding affinity towards ConA. The obtained data show a preference for the α anomer that increases with temperature. This experimental approach can be extended to others systems of biomedical interest by testing human lectins with suitably tailored glycan derivatives. PMID:26580665

  2. Cavity Ring-down Spectroscopic System And Method

    Alquaity, Awad Bin Saud


    A system and method for cavity ring-down spectroscopy can include a pulsed quantum cascade laser, an optical ring-down cavity, a photodetector, and an oscilloscope. The system and method can produce pulse widths of less than 200 ns with bandwidths greater than 300 pm, as well as provide temporal resolution of greater than 10 .mu.s.

  3. Through-space (19) F-(15) N couplings for the assignment of stereochemistry in flubenzimine.

    Ghiviriga, Ion; Rubinski, Miles A; Dolbier, William R


    Through-space (19) F-(15) N couplings revealed the configuration of flubenzimine, with the CF3 group on N4 pointing towards the lone pair of N5. The (19) F-(15) N coupling constants were measured at natural abundance using a spin-state selective indirect-detection pulse sequence. As (15) N-labelled proteins are routinely synthesized for NMR studies, through-space (19) F-(15) N couplings have the potential to probe the stereochemistry of these proteins by (19) F labelling of some amino acids or can reveal the site of docking of fluorine-containing drugs. Copyright © 2016 John Wiley & Sons, Ltd.

  4. Ring-laser gyroscope system using dispersive element(s)

    Smith, David D. (Inventor)


    A ring-laser gyroscope system includes a ring-laser gyroscope (RLG) and at least one dispersive element optically coupled to the RLG's ring-shaped optical path. Each dispersive element has a resonant frequency that is approximately equal to the RLG's lasing frequency. A group index of refraction defined collectively by the dispersive element(s) has (i) a real portion that is greater than zero and less than one, and (ii) an imaginary portion that is less than zero.

  5. Characterization of solid polymer dispersions of active pharmaceutical ingredients by 19F MAS NMR and factor analysis

    Urbanova, Martina; Brus, Jiri; Sedenkova, Ivana; Policianova, Olivia; Kobera, Libor

    In this contribution the ability of 19F MAS NMR spectroscopy to probe structural variability of poorly water-soluble drugs formulated as solid dispersions in polymer matrices is discussed. The application potentiality of the proposed approach is demonstrated on a moderately sized active pharmaceutical ingredient (API, Atorvastatin) exhibiting extensive polymorphism. In this respect, a range of model systems with the API incorporated in the matrix of polvinylpyrrolidone (PVP) was prepared. The extent of mixing of both components was determined by T1(1H) and T1ρ(1H) relaxation experiments, and it was found that the API forms nanosized domains. Subsequently it was found out that the polymer matrix induces two kinds of changes in 19F MAS NMR spectra. At first, this is a high-frequency shift reaching 2-3 ppm which is independent on molecular structure of the API and which results from the long-range polarization of the electron cloud around 19F nucleus induced by electrostatic fields of the polymer matrix. At second, this is broadening of the signals and formation of shoulders reflecting changes in molecular arrangement of the API. To avoid misleading in the interpretation of the recorded 19F MAS NMR spectra, because both the contributions act simultaneously, we applied chemometric approach based on multivariate analysis. It is demonstrated that factor analysis of the recorded spectra can separate both these spectral contributions, and the subtle structural differences in the molecular arrangement of the API in the nanosized domains can be traced. In this way 19F MAS NMR spectra of both pure APIs and APIs in solid dispersions can be directly compared. The proposed strategy thus provides a powerful tool for the analysis of new formulations of fluorinated pharmaceutical substances in polymer matrices.

  6. Ring resonator systems to perform optical communication enhancement using soliton

    Amiri, Iraj Sadegh


    The title explain new technique of secured and high capacity optical communication signals generation by using the micro and nano ring resonators. The pulses are known as soliton pulses which are more secured due to having the properties of chaotic and dark soliton signals with ultra short bandwidth. They have high capacity due to the fact that ring resonators are able to generate pulses in the form of solitons in multiples and train form. These pulses generated by ring resonators are suitable in optical communication due to use the compact and integrated rings system, easy to control, flexibi

  7. Quantitative 19F MR spectroscopy at 3 T to detect heterogeneous capecitabine metabolism in human liver.

    Klomp, D.W.J.; Laarhoven, H.W.M. van; Scheenen, T.W.J.; Kamm, Y.J.L.; Heerschap, A.


    Chemotherapy in non-responding cancer patients leads to unnecessary toxicity. A marker is therefore required that can predict the sensitivity of a specific tumour to chemotherapy, which would enable individualisation of therapy. 19F MR spectroscopy (19F MRS) can be used to monitor the metabolism of

  8. 19F-nuclear magnetic resonance spectroscopy as a tool to ...

    Purpose: 19F-Nuclear magnetic resonance spectroscopy (19F-NMR) was used to study host-guest ... least-squares curve fitting program, KINFIT, to obtain the formation constant of CD-drug complex. ..... It is interesting to note that, methylated.

  9. T-maze performance after developmental exposure to 19F tagged 5-HTP in chicks.

    Dingman, Sherry; Nash, Laurie; Hogan, Jeremy; Branch, Craig


    Chicks were used as a model to investigate behavioral effects of administering a new compound intended for use with magnetic resonance. The compound has multiple 19F atom tags covalently bonded to the indole ring of 5-hydroxytryptophan (PF-5HTP), the immediate precursor to the neurotransmitter serotonin. On incubation Day 17, 5 microg of PF-5-HTP, an equivalent amount of 5-HTP, or just 200 microL of the weak phosphate buffered saline (PBS) vehicle was injected into the airsac of each egg. Three days after hatching, chicks were isolated at the top of a simple T-Maze which, when traversed correctly, enabled them to return to their brood mates. A second trial in the T-Maze was conducted about three hours later. The brief period of isolation at the start of a trial causes social distress in chicks who are reinforced by returning to the brood. The task was selected as being sensitive to functioning of the serotonin pathways whose development might be altered by administering the compound during brain development. Repeated-measures analysis of variance yielded a statistically significant main effect for trial within groups, but no significant difference between injection groups. Administering a low dose of the fluorine tagged compound during development did not impair performance on this T-maze task.

  10. Cell tracking using {sup 19}F magnetic resonance imaging: Technical aspects and challenges towards clinical applications

    Amiri, Houshang [Radboud University Medical Center, Department of Radiology, Nijmegen (Netherlands); Radboud University Medical Center, Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Nijmegen (Netherlands); Srinivas, Mangala; Vries, I.J.M. de [Radboud University Medical Center, Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Nijmegen (Netherlands); Veltien, Andor; Uden, Mark J. van; Heerschap, Arend [Radboud University Medical Center, Department of Radiology, Nijmegen (Netherlands)


    {sup 19}F MRI is emerging as a new imaging technique for cell tracking. It is particularly attractive because of its potential for direct and precise cell quantification. The most important challenge towards in vivo applications is the sensitivity of the technique, i.e. the detection limit in a reasonable imaging time. Optimal sensitivity can be achieved with dedicated {sup 19}F compounds together with specifically adapted hardware and acquisition methods. In this paper we introduce the {sup 19}F MRI technique focusing on these key sensitivity issues and review the state-of-the-art of {sup 19}F MRI and developments towards its clinical use. We calculate {sup 19}F detection limits reported in preclinical cell and clinical {sup 19}F drug studies in terms of tissue concentration in a 1 cm{sup 3} voxel, as an alternate way to compare detection limits. We estimate that a tissue concentration of a few millimoles per litre (mM) of {sup 19}F is required for a human study at a resolution of 1 cm{sup 3}. (orig.)

  11. The thermonuclear production of 19F by Wolf-Rayet stars revisited

    Palacios, A.; Arnould, M.; Meynet, G.


    New models of rotating and non-rotating stars are computed for initial masses between 25 and 120 M_⊙ and for metallicities Z = 0.004, 0.008, 0.020, and 0.040 with the aim of reexamining the wind contribution of Wolf-Rayet (WR) stars to the 19F enrichment of the interstellar medium. Models with an initial rotation velocity υi = 300 km s-1 are found to globally eject less 19F than the non-rotating models. We compare our new predictions with those of Meynet & Arnould (2000, A&A, 355, 176), and demonstrate that the 19F yields are very sensitive to the still uncertain 19F (α ,p) 22Ne rate and to the adopted mass loss rates. Using the recommended mass loss rate values that take into account the clumping of the WR wind and the NACRE reaction rates, when available, we obtain WR 19F yields that are significantly lower than predicted by Meynet & Arnould (2000, A&A, 355, 176) and that would make WR stars non-important contributors to the galactic 19F budget. In view, however, of the large nuclear and mass loss rate uncertainties, we consider that the question of the WR contribution to the galactic 19F remains quite open.

  12. The Rings Node for the Planetary Data System

    Showalter, Mark R.; Bollinger, Kenneth J.; Cuzzi, Jeffrey N.; Nicholson, Philip D.


    The Planetary Data System's Rings Node is devoted to the archiving and distributing of scientific data sets relevant to planetary ring systems. The two major classes of ring data are images and occultation profiles, although a variety of additional data types (e.g. spectra, particle absorption signatures, etc.) are also of interest. A large fraction of our data sets are from the Voyager missions to the outer planets, but Earth-based and Hubble Space Telescope data sets are also represented. Archiving work often includes re-formatting the data into standardized formats and reconstructing some of the data processing steps. The Rings Node also performs a variety of services to support research into these data sets. These services include developing on-line catalogs and information systems, filling orders for data, developing software tools, and coordinating special observing campaigns.

  13. (19)F MRSI of capecitabine in the liver at 7 T using broadband transmit-receive antennas and dual-band RF pulses.

    van Gorp, Jetse S; Seevinck, Peter R; Andreychenko, Anna; Raaijmakers, Alexander J E; Luijten, Peter R; Viergever, Max A; Koopman, Miriam; Boer, Vincent O; Klomp, Dennis W J


    Capecitabine (Cap) is an often prescribed chemotherapeutic agent, successfully used to cure some patients from cancer or reduce tumor burden for palliative care. However, the efficacy of the drug is limited, it is not known in advance who will respond to the drug and it can come with severe toxicity. (19)F Magnetic Resonance Spectroscopy (MRS) and Magnetic Resonance Spectroscopic Imaging (MRSI) have been used to non-invasively study Cap metabolism in vivo to find a marker for personalized treatment. In vivo detection, however, is hampered by low concentrations and the use of radiofrequency (RF) surface coils limiting spatial coverage. In this work, the use of a 7T MR system with radiative multi-channel transmit-receive antennas was investigated with the aim of maximizing the sensitivity and spatial coverage of (19)F detection protocols. The antennas were broadband optimized to facilitate both the (1)H (298 MHz) and (19)F (280 MHz) frequencies for accurate shimming, imaging and signal combination. B1(+) simulations, phantom and noise measurements showed that more than 90% of the theoretical maximum sensitivity could be obtained when using B1(+) and B1(-) information provided at the (1)H frequency for the optimization of B1(+) and B1(-) at the (19)F frequency. Furthermore, to overcome the limits in maximum available RF power, whilst ensuring simultaneous excitation of all detectable conversion products of Cap, a dual-band RF pulse was designed and evaluated. Finally, (19)F MRS(I) measurements were performed to detect (19)F metabolites in vitro and in vivo. In two patients, at 10 h (patient 1) and 1 h (patient 2) after Cap intake, (19)F metabolites were detected in the liver and the surrounding organs, illustrating the potential of the set-up for in vivo detection of metabolic rates and drug distribution in the body.

  14. A ring system detected around the Centaur (10199) Chariklo

    Braga-Ribas, F; Ortiz, J L; Snodgrass, C; Roques, F; Vieira-Martins, R; Camargo, J I B; Assafin, M; Duffard, R; Jehin, E; Pollock, J; Leiva, R; Emilio, M; Machado, D I; Colazo, C; Lellouch, E; Skottfelt, J; Gillon, M; Ligier, N; Maquet, L; Benedetti-Rossi, G; Gomes, A Ramos; Kervella, P; Monteiro, H; Sfair, R; Moutamid, M El; Tancredi, G; Spagnotto, J; Maury, A; Morales, N; Gil-Hutton, R; Roland, S; Ceretta, A; Gu, S -h; Wang, X -b; Harpsøe, K; Rabus, M; Manfroid, J; Opitom, C; Vanzi, L; Mehret, L; Lorenzini, L; Schneiter, E M; Melia, R; Lecacheux, J; Colas, F; Vachier, F; Widemann, T; Almenares, L; Sandness, R G; Char, F; Perez, V; Lemos, P; Martinez, N; Jørgensen, U G; Dominik, M; Roig, F; Reichart, D E; LaCluyze, A P; Haislip, J B; Ivarsen, K M; Moore, J P; Frank, N R; Lambas, D G


    Until now, rings have been detected in the Solar System exclusively around the four giant planets. Here we report the discovery of the first minor-body ring system around the Centaur object (10199) Chariklo, a body with equivalent radius 124$\\pm$9 km. A multi-chord stellar occultation revealed the presence of two dense rings around Chariklo, with widths of about 7 km and 3 km, optical depths 0.4 and 0.06, and orbital radii 391 and 405 km, respectively. The present orientation of the ring is consistent with an edge-on geometry in 2008, thus providing a simple explanation for the dimming of Chariklo's system between 1997 and 2008, and for the gradual disappearance of ice and other absorption features in its spectrum over the same period. This implies that the rings are partially composed of water ice. These rings may be the remnants of a debris disk, which were possibly confined by embedded kilometre-sized satellites.

  15. CO Gas orbiting around the GG Tauri A triple System: rings beyond the ring ?

    Tang, Ya-Wen; Guilloteau, Stephane; Chapillon, Edwige; Pietu, Vincent; Di Folco, Emmanuel; Bary, Jeff; Beck, Tracy; Beust, Herve; Boehler, Yann; Gueth, Frederic; Hure, Jean-Marc; Pierens, Arnaud; Simon, Michal


    We aim at unveiling the observational imprint of physical mechanisms that govern planetary formation in the young, multiple system GG Tau A. We present ALMA observations of $^{12}$CO and $^{13}$CO 3-2 and continuum at 0.9 mm at 0.35" resolution. The $^{12}$CO gas, found in the cavity of the dust ring where no $^{13}$CO gas is detected, confirms the existence of a CO accretion shock near the circumstellar disk of GG Tau Aa. The outer disk and the hot spot lying at the outer edge of the dust ring are observed both in $^{12}$CO and $^{13}$CO. The gas emission in the outer disk can be radially decomposed in a series of slightly overlapping gaussian rings, suggesting the presence of unresolved gaps. The dip closest to the disk center lies at a radius very close to the CO hot spot location ($\\sim250-260$~au). Studies of the CO excitation conditions reveal that the outer disk remains in the shadow of the ring. The hot spot probably results from local heating processes. The two latter points strongly support the hypo...

  16. Clump detections and limits on moons in Jupiter's ring system.

    Showalter, Mark R; Cheng, Andrew F; Weaver, Harold A; Stern, S Alan; Spencer, John R; Throop, Henry B; Birath, Emma M; Rose, Debi; Moore, Jeffrey M


    The dusty jovian ring system must be replenished continuously from embedded source bodies. The New Horizons spacecraft has performed a comprehensive search for kilometer-sized moons within the system, which might have revealed the larger members of this population. No new moons were found, however, indicating a sharp cutoff in the population of jovian bodies smaller than 8-kilometer-radius Adrastea. However, the search revealed two families of clumps in the main ring: one close pair and one cluster of three to five. All orbit within a brighter ringlet just interior to Adrastea. Their properties are very different from those of the few other clumpy rings known; the origin and nonrandom distribution of these features remain unexplained, but resonant confinement by Metis may play a role.

  17. Determination of {alpha}-widths in {sup 19}F relevant to fluorine nucleosynthesis

    Oliveira, F. de [CSNSM, 91 - Orsay (France); Coc, A. [CSNSM, 91 - Orsay (France); Aguer, P. [CSNSM, 91 - Orsay (France); Angulo, C. [CSNSM, 91 - Orsay (France); Bogaert, G. [CSNSM, 91 - Orsay (France); Kiener, J. [CSNSM, 91 - Orsay (France); Lefebvre, A. [CSNSM, 91 - Orsay (France); Tatischeff, V. [CSNSM, 91 - Orsay (France); Thibaud, J.P. [CSNSM, 91 - Orsay (France); Fortier, S. [Paris-11 Univ., 91 - Orsay (France). Inst. de Physique Nucleaire; Maison, J.M. [Paris-11 Univ., 91 - Orsay (France). Inst. de Physique Nucleaire; Rosier, L. [Paris-11 Univ., 91 - Orsay (France). Inst. de Physique Nucleaire; Rotbard, G. [Paris-11 Univ., 91 - Orsay (France). Inst. de Physique Nucleaire; Vernotte, J. [Paris-11 Univ., 91 - Orsay (France). Inst. de Physique Nucleaire; Arnould, M. [Universite Libre de Bruxelles (Belgium). Inst. d`Astronomie et d`Astrophysique; Jorissen, A. [Universite Libre de Bruxelles (Belgium). Inst. d`Astronomie et d`Astrophysique; Mowlavi, N. [Universite Libre de Bruxelles (Belgium). Inst. d`Astronomie et d`Astrophysique


    Nucleosynthesis of fluorine in the context of helium burning occurs through the {sup 15}N({alpha},{gamma}){sup 19}F reaction. At temperatures where fluorine formation takes place in most astrophysical models, the narrow resonance associated with the 4.378 MeV level of {sup 19}F is expected to dominate the reaction rate, but its strength is not known. We used a {sup 15}N confined gas target to study this level by means of the transfer reaction {sup 15}N({sup 7}Li,t){sup 19}F at 28 MeV. Reaction products were analysed with a split pole magnetic spectrometer and the angular distributions for the first 16 levels of {sup 19}F were extracted. These distributions are fairly well reproduced by FR-DWBA calculations in the framework of an {alpha}-cluster transfer model with a compound nucleus contribution obtained by Hauser-Feshbach calculations. {alpha}-spectroscopic factors were deduced and, for unbound levels, the {alpha}-widths were determined and compared with the existing direct measurements. The {alpha}-width of the level of astrophysical interest (E{sub x} 4.378 MeV) was found to be {Gamma}{sub {alpha}}=1.5 x 10{sup -9} eV, a value 60 times smaller than the commonly used one. The astrophysical consequences for {sup 19}F production in AGB stars are discussed. (orig.).

  18. VLSI neural system architecture for finite ring recursive reduction.

    Zhang, D; Jullien, G A


    The use of neural-like networks to implement finite ring computations has been presented in a previous paper. This paper develops efficient VLSI neural system architecture for the finite ring recursive reduction (FRRR), including module reduction, MSB carry iteration and feedforward processing. These techniques deal with the basic principles involved in constructing a FRRR, and their implementations are efficiently matched to the VLSI medium. Compared with the other structure models for finite ring computation (e.g. modification of binary arithmetic logic and bit-steered ROM's), the FRRR structure has the lowest area complexity in silicon while maintaining a high throughput rate. Examples of several implementations are used to illustrate the effectiveness of the FRRR architecture.

  19. Position Ring System using Anger Type Detectors

    Joel S. Karp, principal investigator


    The overall objective of our project was to develop PET scanners and imaging techniques that achieve high performance and excellent image quality. Our approach was based upon 3-D imaging (no septa) with position-sensitive Anger-logic detectors, whereby the encoding ratio of resolution elements to number of photo-multiplier tube channels is very high. This design led to a series of PET systems that emphasized cost-effectiveness and practicality in a clinical environment.

  20. Statistical significance of non-reproducibility of cross sections measured in dissipative reactions 19F+93Nb

    DONG Yu-Chuan; JIANG Hua; HU Gui-Qing; WANG Qi; LI Song-Lin; TIAN Wen-Dong; LI Zhi-Chang; LU Xiu-Qin; ZHAO Kui; FU Chang-Bo; LIU Jian-Cheng


    Two independent measurements of cross sections for the 19F+93Nb dissipative heavy-ion collision (DHIC) have been performed at incident energies from 100 to 108 MeV in steps of 250 keV. Two independently prepared targets were used respectively with all other experimental conditions being identical in both experiments. The data indicate non-reproducibility of the non-self-averaging oscillation yields in the two measurements. The statistical analysis of this non-reproducibility supports recent theoretical predictions of spontaneous coherence, slow phase randomization and extreme sensitivity in highly excited quantum many-body systems.

  1. Double-tuned radiofrequency coil for (19)F and (1)H imaging.

    Otake, Yosuke; Soutome, Yoshihisa; Hirata, Koji; Ochi, Hisaaki; Bito, Yoshitaka


    We developed a double-tuned radiofrequency (RF) coil using a novel circuit method to double tune for fluorine-19 (19F) and 1H magnetic resonance imaging, whose frequencies are very close to each other. The RF coil consists of 3 parallel-connected series inductor capacitor circuits. A computer simulation for our double-tuned RF coil with a phantom demonstrated that the coil has tuned resonant frequency and high sensitivity for both 19F and 1H. Drug distribution was visualized at 7 tesla using this RF coil and a rat administered perfluoro 15-crown-5-ether emulsion. The double-tune RF coil we developed may be a powerful tool for 19F and 1H imaging.

  2. Magnetism, optical absorbance, and 19F NMR spectra of nafion films with self-assembling paramagnetic networks

    Levin, E. M.; Chen, Q.; Bud' ko, S. L.


    Magnetization, optical absorbance, and {sup 19}F NMR spectra of Nafion transparent films as received and doped with Mn{sup 2+}, Co{sup 2+}, Fe{sup 2+}, and Fe{sup 3+} ions with and without treatment in 1H-1,2,4-triazole (trz) have been studied. Doping of Nafion with Fe{sup 2+} and Co{sup 2+} and their bridging to nitrogen of triazole yields a hybrid self-assembling paramagnetic system that exhibits interesting magnetic and optical properties. These include spin crossover phenomena between high-spin (HS) and low-spin (LS) states in Nafion-Fe{sup 2+}-trz and Nafion-Co{sup 2+}-trz accompanied by thermochromic effects in the visible range induced by temperature. A large shift of the magnetization curve induced by a magnetic field in the vicinity of the HS {leftrightarrow} LS, {approx}220 K, observed for Nafion-Fe{sup 2+}-trz has a rate of {approx}6 K/kOe, which is about three orders of magnitude larger than that in bulk spin crossover Fe{sup 2+} materials. Selective response of {sup 19}F NMR signals on doping with paramagnetic ions demonstrates that NMR can be used as spatially resolved method to study Nafion film with paramagnetic network. Both chemical shift and width of {sup 19}F NMR signals show that SO groups of Nafion, Fe or Co ions, and nitrogen of triazole are bonded whereas they form a spin crossover system. Based on a model of nanosize cylinders proposed for Nafion [K. Schmidt-Rohr and Q. Chen, Nat Mater (2008), 75], we suggest that paramagnetic ions are located inside these cylinders, forming self-assembling magnetically and optically active nanoscale networks.

  3. In vivo imaging of stepwise vessel occlusion in cerebral photothrombosis of mice by 19F MRI.

    Gesa Weise

    Full Text Available BACKGROUND: (19F magnetic resonance imaging (MRI was recently introduced as a promising technique for in vivo cell tracking. In the present study we compared (19F MRI with iron-enhanced MRI in mice with photothrombosis (PT at 7 Tesla. PT represents a model of focal cerebral ischemia exhibiting acute vessel occlusion and delayed neuroinflammation. METHODS/PRINCIPAL FINDINGS: Perfluorocarbons (PFC or superparamagnetic iron oxide particles (SPIO were injected intravenously at different time points after photothrombotic infarction. While administration of PFC directly after PT induction led to a strong (19F signal throughout the entire lesion, two hours delayed application resulted in a rim-like (19F signal at the outer edge of the lesion. These findings closely resembled the distribution of signal loss on T2-weighted MRI seen after SPIO injection reflecting intravascular accumulation of iron particles trapped in vessel thrombi as confirmed histologically. By sequential administration of two chemically shifted PFC compounds 0 and 2 hours after illumination the different spatial distribution of the (19F markers (infarct core/rim could be visualized in the same animal. When PFC were applied at day 6 the fluorine marker was only detected after long acquisition times ex vivo. SPIO-enhanced MRI showed slight signal loss in vivo which was much more prominent ex vivo indicative for neuroinflammation at this late lesion stage. CONCLUSION: Our study shows that vessel occlusion can be followed in vivo by (19F and SPIO-enhanced high-field MRI while in vivo imaging of neuroinflammation remains challenging. The timing of contrast agent application was the major determinant of the underlying processes depicted by both imaging techniques. Importantly, sequential application of different PFC compounds allowed depiction of ongoing vessel occlusion from the core to the margin of the ischemic lesions in a single MRI measurement.

  4. (19)F NMR spectroscopic characterization of the interaction of niflumic acid with human serum albumin.

    Kitamura, Keisuke; Omran, Ahmed A; Takegami, Shigehiko; Tanaka, Rumi; Kitade, Tatsuya


    The interaction of a non-steroidal anti-inflammatory drug, niflumic acid (NFA), with human serum albumin (HSA) has been investigated by (19)F nuclear magnetic resonance (NMR) spectroscopy. A (19)F NMR spectrum of NFA in a buffered (pH 7.4) solution of NaCl (0.1 mol L(-1)) contained a single sharp signal of its CF(3) group 14.33 ppm from the internal reference 2,2,2-trifluoroethanol. Addition of 0.6 mmol L(-1) HSA to the NFA buffer solution caused splitting of the CF(3) signal into two broadened signals, shifted to the lower fields of 14.56 and 15.06 ppm, with an approximate intensity ratio of 1:3. Denaturation of HSA by addition of 3.0 mol L(-1) guanidine hydrochloride (GU) restored a single sharp signal of CF(3) at 14.38 ppm, indicating complete liberation of NFA from HSA as a result of its denaturation. These results suggest that the binding is reversible and occurs in at least two HSA regions. Competitive (19)F NMR experiments using warfarin, dansyl-L: -asparagine, and benzocaine (site I ligands), and L: -tryptophan and ibuprofen (site II ligands) revealed that NFA binds to site I at two different regions, Ia and Ib, in the ratio 1:3. By use of (19)F NMR with NFA as an (19)F NMR probe the nonfluorinated site I-binding drugs sulfobromophthalein and iophenoxic acid were also found to bind sites Ia and Ib, respectively. These results illustrate the usefulness and convenience of (19)F NMR for investigation of the HSA binding of both fluorinated and nonfluorinated drugs.

  5. In vivo tracking of human neural stem cells with 19F magnetic resonance imaging.

    Philipp Boehm-Sturm

    Full Text Available BACKGROUND: Magnetic resonance imaging (MRI is a promising tool for monitoring stem cell-based therapy. Conventionally, cells loaded with ironoxide nanoparticles appear hypointense on MR images. However, the contrast generated by ironoxide labeled cells is neither specific due to ambiguous background nor quantitative. A strategy to overcome these drawbacks is (19F MRI of cells labeled with perfluorocarbons. We show here for the first time that human neural stem cells (NSCs, a promising candidate for clinical translation of stem cell-based therapy of the brain, can be labeled with (19F as well as detected and quantified in vitro and after brain implantation. METHODOLOGY/PRINCIPAL FINDINGS: Human NSCs were labeled with perfluoropolyether (PFPE. Labeling efficacy was assessed with (19F MR spectroscopy, influence of the label on cell phenotypes studied by immunocytochemistry. For in vitro MRI, NSCs were suspended in gelatin at varying densities. For in vivo experiments, labeled NSCs were implanted into the striatum of mice. A decrease of cell viability was observed directly after incubation with PFPE, which re-normalized after 7 days in culture of the replated cells. No label-related changes in the numbers of Ki67, nestin, GFAP, or βIII-tubulin+ cells were detected, both in vitro and on histological sections. We found that 1,000 NSCs were needed to accumulate in one image voxel to generate significant signal-to-noise ratio in vitro. A detection limit of ∼10,000 cells was found in vivo. The location and density of human cells (hunu+ on histological sections correlated well with observations in the (19F MR images. CONCLUSION/SIGNIFICANCE: Our results show that NSCs can be efficiently labeled with (19F with little effects on viability or proliferation and differentiation capacity. We show for the first time that (19F MRI can be utilized for tracking human NSCs in brain implantation studies, which ultimately aim for restoring loss of function after

  6. Probing the Pu4 + magnetic moment in PuF4 with 19F NMR spectroscopy

    Capan, Cigdem; Dempsey, Richard J.; Sinkov, Sergey; McNamara, Bruce K.; Cho, Herman


    The magnetic fields produced by Pu4 + centers have been measured by 19F NMR spectroscopy to elucidate the Pu-F electronic interactions in polycrystalline PuF4. Spectra acquired at applied fields of 2.35 and 7.05 T reveal a linear scaling of the 19F line shape. A model is presented that treats the line broadening and shifts as due to dipolar fields produced by Pu valence electrons in localized noninteracting orbitals. Alternative explanations for the observed line shape involving covalent Pu-F bonding, superexchange interactions, and electronic configurations with enhanced magnetic moments are considered.

  7. SWIFT Observations of the Arp 147 Ring galaxy system

    Fogarty, Lisa; Tecza, Matthias; Clarke, Fraser; Goodsall, Timothy; Houghton, Ryan; Salter, Graeme; Davies, Roger; Kassin, Susan


    We present observations of Arp 147, a galaxy system comprising a collisionally-created ring galaxy and an early-type galaxy, using the Oxford SWIFT integral field spectrograph (IFS) at the 200-inch Hale telescope. We derive spatially resolved kinematics from the IFS data and use these to study the interaction between the two galaxies. We find the edge-to-edge expansion velocity of the ring is 225 +/- 8 km/s, implying an upper limit on the timescale for the collision of 50 Myrs. We also calculate that the angle of impact for the collision is between 33 degrees-54 degrees, where 0 degrees would imply a perpendicular collision. The ring galaxy is strongly star-forming with the star formation likely to have been triggered by the collision between the two galaxies. We measure some key physical parameters in an integrated and spatially resolved manner for the ring galaxy. Using observed B-I colours and the H-alpha equivalent widths, we conclude that two stellar components (a young and an old population) are require...

  8. AGB nucleosynthesis: The 19F(α, p)22Ne reaction at astrophysical energies

    D'Agata, G.; Pizzone, R. G.; Spitaleri, C.; Blagus, S.; Figuera, P.; Grassi, L.; Guardo, G. L.; Gulino, M.; Hayakawa, S.; Indelicato, I.; Kshetri, R.; La Cognata, M.; Lamia, L.; Lattuada, M.; Mijatović, T.; Milin, M.; Miljanic, D.; Prepolec, L.; Sergi, M. L.; Skukan, N.; Soic, N.; Tokic, V.; Tumino, A.; Uroic, M.


    Learning how 19F is produced and destructed in AGB-stars is crucial. Fluorine abundance is in fact important, given that it is strongly tied to standard and extra-mixing processes taking place in AGB-stars. This kind of objects are considered to be the main sources of fluorine in galactic environment, in which experimental abundances are far overestimated. For this reason the reaction 19F(α, p)22Ne, that represents the main destruction channel in He-rich environment, was studied at energies corresponding to T˜2.108 K. Such reaction has been studied with direct method at Ebeam = 1100 keV for alpha particles impinging on a fluorine target, corresponding to EC.M. ˜ 900 keV, still far from the Gamow window, placed at 390÷800 keV, below the Coulomb barrier (3.81 MeV). An experiment was performed at Rujer Boskovic Institut (Zagreb), applying the Trojan Horse Method. With this experimental procedure we were able to select the quasi-free contribution coming from 6Li(19F,p 22Ne)2H at Ebeam = 6 MeV at kinematically useful angles. We measured the 19F(α, p)22Ne at 0 MeV ≤ EC.M ≤ 0.9 MeV, extracting the two body cross-section in absolute units at energies of astrophysical interest.

  9. PLGA-encapsulated perfluorocarbon nanoparticles for simultaneous visualization of distinct cell populations by (19)F MRI

    Srinivas, M.; Tel, J.; Schreibelt, G.; Bonetto, F.J.; Cruz, L.J.; Amiri, H.; Heerschap, A.; Figdor, C.G.; Vries, I.J.M. de


    AIM: In vivo imaging using (19)F MRI is advantageous, due to its ability to quantify cell numbers, but is limited for a lack of suitable labels. Here, we formulate two stable and clinically applicable labels for tracking two populations of primary human dendritic cells (DCs) simultaneously. MATERIAL

  10. A 19F NMR study of C-I....pi- halogen bonding

    Hauchecorne, Dieter; vand er Veken, Benjamin J.; Herrebout, Wouter A.


    The formation of halogen bonded complexes between toluene-d8 and the perfluoroiodopropanes 1-C3F7I and 2-C3F7I has been investigated using 19F NMR spectroscopy. For both Lewis acids, evidence was found for the formation of a C–I⋯π halogen bonded complex. The complex formed is a 1:1 type. Using...

  11. Ab Initio Calculation of 19F NMR Chemical Shielding for Alkaline-earth-metal Fluorides

    CAI,Shu-Hui(蔡淑惠); CHEN,Zhong,(陈忠); LU,Xin(吕鑫); CHEN,Zhi-Wei(陈志伟); WAN,Hui-Lin(万惠霖)


    Gauge-independent atomic orbital (GIAO) method atHartree-Fock (HF) and density functional theory (DFr) lev-els,respectively,was employed to calculate 19F NMR chemi-cal shieldings of solid state alkaline-earth-metal fluorides MF2 (M = Mg,Ca,Sr,Ba).The results show that,although thecalculated19F chemical shieldings tend to be larger than the experinental values,they have a fairly good linear relation-ship with the observed ones.The calculated results based on different combinations of basis sets show that the B3LYP (ahybrid of DFT with HF) predictions are greatly superior tothe I-IF predictions.When a basis set of metal atom with ef- fecfive core potential (ECP) has well representation of valencewavefunction,especially wavefuncfion of d component,andproper definition of core electron nmnher,it can be applied toobtain 19F chemical shielding which is dose to that of all-elec-tron calculation.Tne variation of 19F chemical shielding of al-kaline-earth-metal fluorides correlates well with the latticefactor A/R2.``

  12. Glycosylation intermediates studied using low temperature 1H- and 19F-DOSY NMR

    Qiao, Yan; Ge, Wenzhi; Jia, Lingyu


    Low temperature 1H- and 19F-DOSY have been used for analyzing reactive intermediates in glycosylation reactions, where a glycosyl trichloroacetimidate donor has been activated using different catalysts. The DOSY protocols have been optimized for low temperature experiments and provided new insight...

  13. Upgrade of the PF Ring Vacuum Control System

    Tanimoto, Yasunori; Obina, Takashi


    Having been operated for more than two decades, the PF ring vacuum control system had become superannuated. The system reliability had been degraded and the maintenance work had been difficult. In addition, the device operability had not been high because the operating software, written in BASIC, had been running in a stand-alone computer. In the summer of 2004, the vacuum control system was upgraded to solve these problems. In this upgrade, the operating system was constructed in the EPICS environment. And numerous NIM modules composing hardware interfaces between vacuum device controllers and the operating computers were replaced by reliable PLCs.




    Frisch-ring CdZnTe detectors have demonstrated good energy resolution for identifying isotopes, <1% FWHM at 662 keV, and good efficiency for detecting gamma rays. We will fabricate and test at Brookhaven National Laboratory an integrated module of a 64-element array of 6 x 6 x 12 mm{sup 3} Frisch-ring detectors, coupled with a readout electronics system. It supports 64 readout channels, and includes front-end electronics, signal processing circuit, USB interface and high-voltage power supply. The data-acquisition software is used to process the data stream, which includes amplitude and timing information for each detected event. This paper describes the design and assembly of the detector modules, readout electronics, and a conceptual prototype system. Some test results are also reported.

  15. Saturated fusion systems as idempotents in the double Burnside ring

    Ragnarsson, Kari


    We give a new, unexpected characterization of saturated fusion systems on a p-group S in terms of idempotents in the p-local double Burnside ring of S that satisfy a Frobenius reciprocity relation, and reformulate fusion-theoretic phenomena in the language of idempotents. Interpreting our results in stable homotopy, we answer a long-standing question on stable splittings of classifying spaces of finite groups, and generalize the Adams--Wilkerson criterion for recognizing rings of invariants in the cohomology of an elementary abelian p-group. Applying our results to p-local finite groups, we show that p-local finite groups are equivalent to retractive transfer triples.

  16. High-resolution (19)F MAS NMR spectroscopy: structural disorder and unusual J couplings in a fluorinated hydroxy-silicate.

    Griffin, John M; Yates, Jonathan R; Berry, Andrew J; Wimperis, Stephen; Ashbrook, Sharon E


    High-resolution (19)F magic angle spinning (MAS) NMR spectroscopy is used to study disorder and bonding in a crystalline solid. (19)F MAS NMR reveals four distinct F sites in a 50% fluorine-substituted deuterated hydrous magnesium silicate (clinohumite, 4Mg(2)SiO(4)·Mg(OD(1-x)F(x))(2) with x = 0.5), indicating extensive structural disorder. The four (19)F peaks can be assigned using density functional theory (DFT) calculations of NMR parameters for a number of structural models with a range of possible local F environments generated by F(-)/OH(-) substitution. These assignments are supported by two-dimensional (19)F double-quantum MAS NMR experiments that correlate F sites based on either spatial proximity (via dipolar couplings) or through-bond connectivity (via scalar, or J, couplings). The observation of (19)F-(19)F J couplings is unexpected as the fluorines coordinate Mg atoms and the Mg-F interaction is normally considered to be ionic in character (i.e., there is no formal F-Mg-F covalent bonding arrangement). However, DFT calculations predict significant (19)F-(19)F J couplings, and these are in good agreement with the splittings observed in a (19)F J-resolved MAS NMR experiment. The existence of these J couplings is discussed in relation to both the nature of bonding in the solid state and the occurrence of so-called "through-space" (19)F-(19)F J couplings in solution. Finally, we note that we have found similar structural disorder and spin-spin interactions in both synthetic and naturally occurring clinohumite samples.

  17. [Qualitative and quantitative analysis of fluoxetine hydrochloride by 19F NMR].

    Yang, Bai-Qin; Kong, Er-Li; Xue, Xiao-Di; Zhao, Shou-Qian; Lin, Shrong-Shi


    The chemical shift of fluoxetine hydrochloride appears at delta 14.15 in 19F NMR analysis. The delta moved upfield slightly from 14.158 to 14.145 when the concentration of solution became diluted from 2.00 to 0.05 mmol x L(-1). Spiking test was suggested to confirm the existence of the compound for qualitative analysis. 19F NMR detection sensitivity test illustrated that a concentration of 17 mg in 1 L water could be detected while the sample was scanned 500 times with optimum parameters. In quantitative analysis, standard curve of concentration versus fluorine signal intensity was proposed to determine the amount of fluoxetine. Long capillary tube containing trifluoroacetic acid was used as internal standard for the integration measurements and straight line was obtained with good fitting. Direct additions of trifluoroethanol to fluoxetine solutions gave a poorer standard curve.

  18. Novel fluorinated ligands for gold nanoparticle labelling with applications in (19)F-MRI.

    Michelena, Olatz; Padro, Daniel; Carrillo-Carrión, Carolina; Del Pino, Pablo; Blanco, Jorge; Arnaiz, Blanca; Parak, Wolfgang J; Carril, Mónica


    Novel fluorinated ligands for gold nanoparticle labelling have been designed and synthesised. Several types of gold nanoparticles have been prepared in the presence of these fluorinated ligands alone, or in combination with non-fluorinated ligands. Their colloidal stability in water and other solvents was tested and the magnetic resonance properties of the so-obtained nanoparticles were also assessed in detail. (1)H and (19)F-NMR spectra were evaluated and MRI phantoms of the most promising nanoparticles were successfully measured in (19)F-MRI. The MRI signal to noise ratio was related to the fluorine concentration and compared with ICP-MS data to correlate the real concentration of fluorine grafted onto the nanoparticles with the actually active fluorine in MRI.

  19. A 19F NMR study of C-I....pi- halogen bonding

    Hauchecorne, Dieter; vand er Veken, Benjamin J.; Herrebout, Wouter A.;


    The formation of halogen bonded complexes between toluene-d8 and the perfluoroiodopropanes 1-C3F7I and 2-C3F7I has been investigated using 19F NMR spectroscopy. For both Lewis acids, evidence was found for the formation of a C–I⋯π halogen bonded complex. The complex formed is a 1:1 type. Using sp...

  20. Probe-Specific Procedure to Estimate Sensitivity and Detection Limits for 19F Magnetic Resonance Imaging

    Taylor, Alexander J.; Granwehr, Josef; Lesbats, Clémentine; Krupa, James L.; Six, Joseph S.; Pavlovskaya, Galina E.; Thomas, Neil R.; Auer, Dorothee P.; Meersmann, Thomas; Faas, Henryk M.


    Due to low fluorine background signal in vivo, 19F is a good marker to study the fate of exogenous molecules by magnetic resonance imaging (MRI) using equilibrium nuclear spin polarization schemes. Since 19F MRI applications require high sensitivity, it can be important to assess experimental feasibility during the design stage already by estimating the minimum detectable fluorine concentration. Here we propose a simple method for the calibration of MRI hardware, providing sensitivity estimates for a given scanner and coil configuration. An experimental “calibration factor” to account for variations in coil configuration and hardware set-up is specified. Once it has been determined in a calibration experiment, the sensitivity of an experiment or, alternatively, the minimum number of required spins or the minimum marker concentration can be estimated without the need for a pilot experiment. The definition of this calibration factor is derived based on standard equations for the sensitivity in magnetic resonance, yet the method is not restricted by the limited validity of these equations, since additional instrument-dependent factors are implicitly included during calibration. The method is demonstrated using MR spectroscopy and imaging experiments with different 19F samples, both paramagnetically and susceptibility broadened, to approximate a range of realistic environments. PMID:27727294

  1. Mapping In Vivo Tumor Oxygenation within Viable Tumor by 19F-MRI and Multispectral Analysis

    Yunzhou Shi


    Full Text Available Quantifying oxygenation in viable tumor remains a major obstacle toward a better understanding of the tumor microenvironment and improving treatment strategies. Current techniques are often complicated by tumor heterogeneity. Herein, a novel in vivo approach that combines 19F magnetic resonance imaging (19F-MRIR1 mapping with diffusionbased multispectral (MS analysis is introduced. This approach restricts the partial pressure of oxygen (pO2 measurements to viable tumor, the tissue of therapeutic interest. The technique exhibited sufficient sensitivity to detect a breathing gas challenge in a xenograft tumor model, and the hypoxic region measured by MS 19F-MRI was strongly correlated with histologic estimates of hypoxia. This approach was then applied to address the effects of antivascular agents on tumor oxygenation, which is a research question that is still under debate. The technique was used to monitor longitudinal pO2 changes in response to an antibody to vascular endothelial growth factor (B20.4.1.1 and a selective dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor (GDC-0980. GDC-0980 reduced viable tumor pO2 during a 3-day treatment period, and a significant reduction was also produced by B20.4.1.1. Overall, this method provides an unprecedented view of viable tumor pO2 and contributes to a greater understanding of the effects of antivascular therapies on the tumor's microenvironment.

  2. High resolution upgrade of the ATF damping ring BPM system

    Terunuma, N.; Urakawa, J.; /KEK, Tsukuba; Frisch, J.; May, J.; McCormick, D.; Nelson, J.; Seryi, A.; Smith, T.; Woodley, M.; /SLAC; Briegel, C.; Dysert, R.; /Fermilab


    A beam position monitor (BPM) upgrade at the KEK Accelerator Test Facility (ATF) damping ring has been accomplished in its first stage, carried out by a KEK/FNAL/SLAC collaboration under the umbrella of the global ILC R&D effort. The upgrade consists of a high resolution, high reproducibility read-out system, based on analog and digital downconversion techniques, digital signal processing, and also tests a new automatic gain error correction schema. The technical concept and realization, as well as preliminary results of beam studies are presented.

  3. O-Ring sealing arrangements for ultra-high vacuum systems

    Kim, Chang-Kyo; Flaherty, Robert


    An all metal reusable O-ring sealing arrangement for sealing two concentric tubes in an ultra-high vacuum system. An O-ring of a heat recoverable alloy such as Nitinol is concentrically positioned between protruding sealing rings of the concentric tubes. The O-ring is installed between the tubes while in a stressed martensitic state and is made to undergo a thermally induced transformation to an austenitic state. During the transformation the O-ring expands outwardly and contracts inwardly toward a previously sized austenitic configuration, thereby sealing against the protruding sealing rings of the concentric tubes.

  4. Approaches to the assignment of {sup 19}F resonances from 3-fluorophenylalanine labeled calmodulin using solution state NMR

    Kitevski-LeBlanc, Julianne L.; Evanics, Ferenc; Scott Prosser, R., E-mail: scott.prosser@utoronto.c [University of Toronto, Department of Chemistry (Canada)


    Traditional single site replacement mutations (in this case, phenylalanine to tyrosine) were compared with methods which exclusively employ {sup 15}N and {sup 19}F-edited two- and three-dimensional NMR experiments for purposes of assigning {sup 19}F NMR resonances from calmodulin (CaM), biosynthetically labeled with 3-fluorophenylalanine (3-FPhe). The global substitution of 3-FPhe for native phenylalanine was tolerated in CaM as evidenced by a comparison of {sup 1}H-{sup 15}N HSQC spectra and calcium binding assays in the presence and absence of 3-FPhe. The {sup 19}F NMR spectrum reveals six resolved resonances, one of which integrates to three 3-FPhe species, making for a total of eight fluorophenylalanines. Single phenylalanine to tyrosine mutants of five phenylalanine positions resulted in {sup 19}F NMR spectra with significant chemical shift perturbations of the remaining resonances, and provided only a single definitive assignment. Although {sup 1}H-{sup 19}F heteronucleclear NOEs proved weak, {sup 19}F-edited {sup 1}H-{sup 1}H NOESY connectivities were relatively easy to establish by making use of the {sup 3}J{sub FH} coupling between the fluorine nucleus and the adjacent fluorophenylalanine {delta} proton. {sup 19}F-edited NOESY connectivities between the {delta} protons and {alpha} and {beta} nuclei in addition to {sup 15}N-edited {sup 1}H, {sup 1}H NOESY crosspeaks proved sufficient to assign 4 of 8 {sup 19}F resonances. Controlled cleavage of the protein into two fragments using trypsin, and a repetition of the above 2D and 3D techniques resulted in unambiguous assignments of all 8 {sup 19}F NMR resonances. Our studies suggest that {sup 19}F-edited NOESY NMR spectra are generally adequate for complete assignment without the need to resort to mutational analysis.

  5. Progress of the stochastic cooling system of the Collector Ring

    Dimopoulou, C; Bohm, R; Dolinskyy, O; Franzke, B; Hettrich, R; Maier, W; Menges, R; Nolden, F; Peschke, C; Petri, P; Steck, M; Thorndahl, L


    An overview of the recent achievements and ongoing developments for the stochastic cooling system of the Collector Ring is given. In focus are the hardware developments as well as the progress in predicting the system performance. The system operates in the frequency band 1-2 GHz, it has to provide fast 3D cooling of antiproton, rare isotope and stable heavy ion beams. The main challenges are (i) the cooling of antiprotons by means of cryogenic movable pick-up electrodes and (ii) the fast two-stage cooling (pre-cooling by the Palmer method, followed by the notch filter method) of the hot rare isotope beams (RIBs). Recently, a novel code for simulating the cooling process in the time domain has been developed at CERN. First results for the momentum cooling for heavy ions in the CR will be shown in comparison with results obtained in the frequency domain with the Fokker-Planck approach.

  6. Enantioselective synthesis of the predominant AB ring system of the Schisandra nortriterpenoid natural products.

    Gockel, Birgit; Goh, Shermin S; Puttock, Emma J; Baars, Hannah; Chaubet, Guilhem; Anderson, Edward A


    An enantioselective synthesis of the AB ring system common to the majority of the Schisandra nortriterpenoid natural products is reported. Key steps include a stereospecific ring opening of a trisubstituted epoxide and the use of a β-lactone to enable installation of the gem-dimethyl functionality of the B ring. An acetalization strategy played a key role in a late-stage biomimetic AB ring bicyclization.

  7. Excitation of inclinations in ring-satellite systems

    Borderies, N.; Goldreich, P.; Tremaine, S.


    Resonant gravitational interactions between a ring and a satellite produce secular variations of their orbital inclinations. Interactions at vertical resonances, analogous to Lindblad resonances but involving inclinations instead of eccentricities, excite inclinations. There is no inclination analog of the corotation resonance. An equatorial ring changes the inclination of a nearby satellite in qualitatively the same way that a satellite in an equatorial orbit changes the inclination of a nearby ring. Viscous dissipation in a ring leads to an equilibrium value of its inclination. These results provide a basis for discussing the origins of the inclinations of planetary rings.

  8. Theoretical foundations of synchrotron and storage ring RF systems

    Klingbeil, Harald; Lens, Dieter


    This course-tested text is an ideal starting point for engineers and physicists entering the field of particle accelerators. The fundamentals are comprehensively introduced, derivations of essential results are provided, and a consistent notation style used throughout the book allows readers to quickly familiarize themselves with the field, providing a solid theoretical basis for further studies.   Emphasis is placed on the essential features of the longitudinal motion of charged particle beams, together with the corresponding RF generation and power amplification devices for synchrotron and storage ring systems. In particular, electrical engineering aspects such as closed-loop control of system components are discussed.   The book also offers a valuable resource for graduate students in physics, electronics engineering, or mathematics looking for an introductory and self-contained text on accelerator physics.

  9. Androgynous, Reconfigurable Closed Loop Feedback Controlled Low Impact Docking System With Load Sensing Electromagnetic Capture Ring

    Lewis, James L. (Inventor); Carroll, Monty B. (Inventor); Morales, Ray H. (Inventor); Le, Thang D. (Inventor)


    The present invention relates to a fully androgynous, reconfigurable closed loop feedback controlled low impact docking system with load sensing electromagnetic capture ring. The docking system of the present invention preferably comprises two Docking- assemblies, each docking assembly comprising a load sensing ring having an outer face, one of more electromagnets, one or more load cells coupled to said load sensing ring. The docking assembly further comprises a plurality of actuator arms coupled to said load sensing ring and capable of dynamically adjusting the orientation of said load sensing ring and a reconfigurable closed loop control system capable of analyzing signals originating from said plurality of load cells and of outputting real time control for each of the actuators. The docking assembly of the present invention incorporates an active load sensing system to automatically dynamically adjust the load sensing ring during capture instead of requiring significant force to push and realign the ring.

  10. 19F NMR method for the determination of quality of virgin olive oil

    Zhou, L. L.


    Full Text Available This paper reported a potential analytical technique based on NMR spectroscopy for the determination of quality of olive oil. The model compounds with active hydrogen, including free sterols, free aliphatic alcohols, phenolics, and free fatty acids were determined by 19F NMR upon derivation with 4-fluorobenzoyl chloride. Integration of the appropriate signals of the derivatives of the compounds in the corresponding 19F NMR spectrum allows for the quantification of these compounds. 37 Samples of commercial olive oil and 5 samples of other plant oils were determined by 19F NMR. The amount of diglycerides and the ratio of 1,2-diglycerides to the total amount of diglycerides were analyzed to monitor whether extra virgin olive oil was adulterated with low price olive oil and other plant oils or not. The results showed that the total diglyceride content should not be higher than 2.5% and the ratio (D of 1,2-diglycerides to total diglycerides should be higher than 0.35 for extra virgin olive oil. This method is an easier, simpler, safer, faster and more reliable technique for the determination of the quality of olive oil and can also be extended to monitoring the quality of ordinary edible oils.En este trabajo se describe una técnica analítica basada en la espectroscopía de RMN para determinar la calidad del aceite de oliva. Los compuestos modelo con hidrógeno activo, incluyendo esteroles libres, alcoholes alifáticos libres, compuestos fenólicos, ácidos grasos libres se determinaron por 19F RMN derivatizados con cloruro de 4-fluorobenzoilo. La integración de las señales apropiadas de los derivados de los compuestos en el correspondiente espectro de 19F RMN permite la cuantificación de estos compuestos. 37 muestras de aceites de oliva comerciales y 5 muestras de otros aceites vegetales se determinaron por 19F RMN. La cantidad de diglicéridos y la proporción de los 1,2-diglicéridos a la cantidad total de diglicéridos se analizaron para

  11. Sterol Ring System Oxidation Pattern in Marine Sponges

    S. Ramakrishna Rao


    Full Text Available Abstract: The marine sponges (Porifera are a unique group of sedentary organisms from which several novel natural products are reported, many of which have useful biological activities. In producing unusual sterols, they occupy a preeminent position among the various groups of organisms. The polar sterols of sponges reported as at the end of the year 2002 number about 250; their ring structure changing a hundred times. The oxidation pattern in the sterol ring system, from the point of view of biogenesis seems to be mainly of four types. Each sponge species is able to produce sterols fitting into one of the four main biogenetic pathways viz., (i 3β-hydroxy-Δ5-sterol pathway, (ii 3β-hydroxy-Δ7-sterol pathway, (iii 3β-hydroxy-Δ5,7-sterol pathway, and (iv 3α-hydroxy sterol pathway.

  12. Analysis of Cross-Polarization Dynamics between Two Abundant Nuclei, 19F and 1H, Based on Spin Thermodynamics Theory

    Ando, Shinji; Harris, Robin K.; Reinsberg, Stefan A.


    The phenomenological theory of spin thermodynamics based on the spin temperature hypothesis was employed to describe the cross-polarization (CP) dynamics between two abundant nuclei, 19F and 1H, when the number of fluorine atoms is not substantially less than the number of hydrogens. The influence of T1ρ's of both nuclei and the relative magnitude (heat capacity) of the two spin baths must be incorporated explicitly into the analysis in order to derive values for the parameters involved in the CP dynamics. Numerical calculations were performed to clarify the difference in the evolution of magnetization in variable contact time CP experiments between the 1H → 13C and 1H → 19F cases. A new type of CP-drain experiment was developed for observing the residual 1H magnetization after 1H → 19F CP. 19F direct polarization magic-angle spinning (MAS), 1H → 19F CP, and 1H → 19F CP-drain MAS NMR spectra have been measured for a fluorinated polyimide, 6FDA/ODA. The CP dynamics between 1H and 19F for the polyimide were analyzed on the basis of the spin thermodynamics theory. The constant for polarization transfer (THF) was determined by the analysis using the effective CP parameters, which were directly obtained from the CP and CP-drain experiments, together with independently measured values of TH1ρ and TF1ρ.

  13. Simultaneous 19F-1H medium resolution NMR spectroscopy for online reaction monitoring

    Zientek, Nicolai; Laurain, Clément; Meyer, Klas; Kraume, Matthias; Guthausen, Gisela; Maiwald, Michael


    Medium resolution nuclear magnetic resonance (MR-NMR) spectroscopy is currently a fast developing field, which has an enormous potential to become an important analytical tool for reaction monitoring, in hyphenated techniques, and for systematic investigations of complex mixtures. The recent developments of innovative MR-NMR spectrometers are therefore remarkable due to their possible applications in quality control, education, and process monitoring. MR-NMR spectroscopy can beneficially be applied for fast, non-invasive, and volume integrating analyses under rough environmental conditions. Within this study, a simple 1/16″ fluorinated ethylene propylene (FEP) tube with an ID of 0.04″ (1.02 mm) was used as a flow cell in combination with a 5 mm glass Dewar tube inserted into a benchtop MR-NMR spectrometer with a 1H Larmor frequency of 43.32 MHz and 40.68 MHz for 19F. For the first time, quasi-simultaneous proton and fluorine NMR spectra were recorded with a series of alternating 19F and 1H single scan spectra along the reaction time coordinate of a homogeneously catalysed esterification model reaction containing fluorinated compounds. The results were compared to quantitative NMR spectra from a hyphenated 500 MHz online NMR instrument for validation. Automation of handling, pre-processing, and analysis of NMR data becomes increasingly important for process monitoring applications of online NMR spectroscopy and for its technical and practical acceptance. Thus, NMR spectra were automatically baseline corrected and phased using the minimum entropy method. Data analysis schemes were designed such that they are based on simple direct integration or first principle line fitting, with the aim that the analysis directly revealed molar concentrations from the spectra. Finally, the performance of 1/16″ FEP tube set-up with an ID of 1.02 mm was characterised regarding the limit of detection (LOQ (1H) = 0.335 mol L-1 and LOQ (19F) = 0.130 mol L-1 for trifluoroethanol in

  14. MNDO/GIAO perturbation calculation of 13C and 19F magnetic shielding constants

    游效曾; 吴伟雄; 方维海


    The basic approximation of the MNDO method is applied to the SCF-MO theory of nu-clear magnetic shielding constants.Gauge-invariant atomic orbitais(GIAO)and derived equations are used to cal-culate NMR chemical shifts.A more simple and effective calculation of integration for operators 1/rM,LM andLM/rM described in our previous paper is used.By proper selection of MNDO parameters together with thetwo-center approximation,a satisfactory agreement between computational and experimental 13C and 19F chemi-cal shifts is obtained for a representative set of fluorides.

  15. Fluorinated Boronic Acid-Appended Bipyridinium Salts for Diol Recognition and Discrimination via (19)F NMR Barcodes.

    Axthelm, Jörg; Görls, Helmar; Schubert, Ulrich S; Schiller, Alexander


    Fluorinated boronic acid-appended benzyl bipyridinium salts, derived from 4,4'-, 3,4'-, and 3,3'-bipyridines, were synthesized and used to detect and differentiate diol-containing analytes at physiological conditions via (19)F NMR spectroscopy. An array of three water-soluble boronic acid receptors in combination with (19)F NMR spectroscopy discriminates nine diol-containing bioanalytes--catechol, dopamine, fructose, glucose, glucose-1-phosphate, glucose-6-phosphate, galactose, lactose, and sucrose--at low mM concentrations. Characteristic (19)F NMR fingerprints are interpreted as two-dimensional barcodes without the need of multivariate analysis techniques.




    Full Text Available The introduction of pervasive devices and mobile devices has led to immense growth of real time distributed processing. In such context reliability of the computing environment is very important. Reliability is the probability that the devices, links, processes, programs and files work efficiently for the specified period of time and in the specified condition. Distributed systems are available as conventional ring networks, clusters and agent based systems. Reliability of such systems is focused. These networks are heterogeneous and scalable in nature. There are several factors, which are to be considered for reliability estimation. These include the application related factors like algorithms, data-set sizes, memory usage pattern, input-output, communication patterns, task granularity and load-balancing. It also includes the hardware related factors like processor architecture, memory hierarchy, input-output configuration and network. The software related factors concerning reliability are operating systems, compiler, communication protocols, libraries and preprocessor performance. In estimating the reliability of a system, the performance estimation is an important aspect. Reliability analysis is approached using probability.

  17. Keck Adaptive Optics Observations of Neptune's Ring and Satellite Keck Adaptive Optics Observations of Neptune's Ring and Satellite System

    de Pater, I.; Gibbard, S.; Martin, S.; Marchis, F.; Roe, H. G.; Macintosh, B.


    We observed Neptune, its satellites and ring system on UT 27 and 28 July 2002, with NIRC2 on the 10-m Keck II telescope at 2.2 micron. The total field of view was 10". Each image was integrated for 1 minute; on the first day we had a total of 18 frames, and 33 images on the second day, each spread out over a time interval of 1-2 hours. The complete Adams and Le Verrier rings are visible on each day, after combining all images. In the regions away from the ring arcs, we find that the Le Verrier ring is brighter (up to 20-40%) than the Adams ring. The ring arcs are readily apparent in combinations of the data that take into account Keplerian motion. The ring arc positions are in close agreement with Nicholson et al's (1995) result, as in HST/NICMOS images (Dumas et al. 2002). The Egalite ring has broadened even more since observed with HST/NICMOS in 1998, and is clearly the brightest ring arc. Liberte has decreased in intensity since Voyager and NICMOS. Courage was extremely faint in our images. The satellites Proteus, Larissa, Galatea and Despina are easily seen on individual frames. Thalassa is detected after properly shifting/rotating and adding several frames. This is the first time since the Voyager flybys that Thalassa is detected. Preliminary astrometric measurements suggest the satellites Larissa and Galathea, relative to Proteus, to be off from their nominal (JPL Horizons) positions by 0.3", and Despina by 0.1". Recent results indicate that Proteus is offset by 0.1" compared to Triton (Martins et al. 2003). Preliminary I/F values are 0.06 for Proteus, 0.045 for Larissa and Galatea, and 0.03 for Despina and Thalassa. These observations were supported by the National Science Foundation Science and Technology Center for Adaptive Optics, managed by the University of California at Santa Cruz under cooperative agreement No. AST-9876783

  18. Hexaphyrin as a Potential Theranostic Dye for Photothermal Therapy and 19F Magnetic Resonance Imaging.

    Higashino, Tomohiro; Nakatsuji, Hirotaka; Fukuda, Ryosuke; Okamoto, Haruki; Imai, Hirohiko; Matsuda, Tetsuya; Tochio, Hidehito; Shirakawa, Masahiro; Tkachenko, Nikolai; Hashida, Mitsuru; Murakami, Tatsuya; Imahori, Hiroshi


    meso-Aryl substituted expanded porphyrins have two potential key features suitable for theranostic agents, excellent absorption in near infrared (NIR) region and possible introduction of multiple fluorine atoms at structurally nearly equivalent positions. Herein, hexaphyrin (hexa) was synthesized using 2,6-bis(trifluoromethyl)-4-formyl benzoate and pyrrole and evaluated as a novel theranostic expanded porphyrin possessing the above key features. Under NIR light illumination hexa showed intense photothermal and weak photodynamic effects, which were most likely due to its low-lying excited states close to a singlet oxygen. This sustained photothermal effect caused the ablation of cancer cells more effectively than the photodynamic effect of indocyanine green, a clinically used dye. In addition, hexa@cpHDL revealed potential for use in visualization of tumors by 19F magnetic resonance imaging (MRI) due to the presence of the multiple fluorine atoms. These results shed light on a latent utility of expanded porphyrins as theranostic agents in both photothermal therapy and 19F MRI.


    Stefanko, D.; Langton, C.


    High-level waste (HLW) tanks 18-F and 19-F have been isolated from FTF facilities. To complete operational closure the tanks will be filled with grout for the purpose of: (1) physically stabilizing the tanks, (2) limiting/eliminating vertical pathways to residual waste, (3) entombing waste removal equipment, (4) discouraging future intrusion, and (5) providing an alkaline, chemical reducing environment within the closure boundary to control speciation and solubility of select radionuclides. This report documents the results of a four cubic yard bulk fill scale up test on the grout formulation recommended for filling Tanks 18-F and 19-F. Details of the scale up test are provided in a Test Plan. The work was authorized under a Technical Task Request (TTR), HLE-TTR-2011-008, and was performed according to Task Technical and Quality Assurance Plan (TTQAP), SRNL-RP-2011-00587. The bulk fill scale up test described in this report was intended to demonstrate proportioning, mixing, and transportation, of material produced in a full scale ready mix concrete batch plant. In addition, the material produced for the scale up test was characterized with respect to fresh properties, thermal properties, and compressive strength as a function of curing time.

  20. Tracking Perfluorocarbon Nanoemulsion Delivery by 19F MRI for Precise High Intensity Focused Ultrasound Tumor Ablation

    Shin, Soo Hyun; Park, Eun-Joo; Min, Changki; Choi, Sun Il; Jeon, Soyeon; Kim, Yun-Hee; Kim, Daehong


    Perfluorocarbon nanoemulsions (PFCNEs) have recently been undergoing rigorous study to investigate their ability to improve the therapeutic efficacy of tumor ablation by high intensity focused ultrasound (HIFU). For precise control of PFCNE delivery and thermal ablation, their accumulation and distribution in a tumor should be quantitatively analyzed. Here, we used fluorine-19 (19F) magnetic resonance imaging (MRI) to quantitatively track PFCNE accumulation in a tumor, and analyzed how intra-tumoral PFCNE quantities affect the therapeutic efficacy of HIFU treatment. Ablation outcomes were assessed by intra-voxel incoherent motion analysis and bioluminescent imaging up to 14 days after the procedure. Assessment of PFCNE delivery and treatment outcomes showed that 2-3 mg/mL of PFCNE in a tumor produces the largest ablation volume under the same HIFU insonation conditions. Histology showed varying degrees of necrosis depending on the amount of PFCNE delivered. 19F MRI promises to be a valuable platform for precisely guiding PFCNE-enhanced HIFU ablation of tumors. PMID:28255351

  1. Results from a survey of the dynamics shaping Uranus' Mab/μ-ring system

    Kumar, Kartik; de Pater, Imke; Showalter, Mark R.


    Based on Hubble Space Telescope (HST) data, Showalter and Lissauer (2006) reported the discovery of two faint rings beyond Uranus’ main rings: the ν- and μ- rings. They constitute Uranus' outer ring system and are located beyond the ɛ-ring but interior to the large classical moons. After co-adding a series of HST images, Showalter and Lissauer (2006) obtained radial profiles for both new rings. They discovered that the peak radial intensity of the μ-ring aligns closely with the orbit of Mab. Along with numerous other observations, this points to the fact that the Mab/μ-ring system is highly coupled.The discovery of the μ-ring has led to open questions about dust dynamics beyond Uranus' main rings. Like Saturn's E-ring, observations reveal that the μ-ring is blue, indicative of a pre-dominance of sub-micron-sized particles (de Pater et al., 2006). The E-ring results from plumes on Enceladus' south pole, however the origin of the μ-ring remains a mystery. The latter is likely fed by ejecta from micro-meteorite impacts with Mab, much like Jupiter's faint rings are regenerated by companion (small) moons (Burns et al., 1999). The μ-ring's steep size-distribution suggests that there is an unknown mechanism at play that hides or removes large dust particles. We present results from an investigation into the forces shaping the μ-ring. To simulate the motion of dust in the Mab/μ-ring system, we developed a numerical toolbox (Dustsim; Kumar et al., 2015) that uses Tudat (Kumar et al., 2012). We performed integrations using Dustsim that included the effects of Uranus' gravity field, titled magnetic moment, solar radiation pressure, and collisions with a putative suite of large μ-ring bodies, hypothesized as the cause of Mab's anomalous orbital motion (Kumar et al., 2014). Following on from previous studies (e.g., Sfair and Giuliatti Winter, 2009; Sfair and Giuliatti Winter, 2012), we present a survey of the expected lifetime of μ-ring dust, as a function of


    Stefanko, D.; Langton, C.


    The United States Department of Energy (US DOE) has determined that Tanks 18-F and 19-F have met the F-Tank Farm (FTF) General Closure Plan Requirements and are ready to be permanently closed. The high-level waste (HLW) tanks have been isolated from FTF facilities. To complete operational closure they will be filled with grout for the purpose of: (1) physically stabilizing the tanks, (2) limiting/eliminating vertical pathways to residual waste, (3) discouraging future intrusion, and (4) providing an alkaline, chemical reducing environment within the closure boundary to control speciation and solubility of select radionuclides. Bulk waste removal and heel removal equipment remain in Tanks 18-F and 19-F. This equipment includes the Advance Design Mixer Pump (ADMP), transfer pumps, transfer jets, standard slurry mixer pumps, equipment-support masts, sampling masts, dip tube assemblies and robotic crawlers. The present Tank 18 and 19-F closure strategy is to grout the equipment in place and eliminate vertical pathways by filling voids in the equipment to vertical fast pathways and water infiltration. The mock-up tests described in this report were intended to address placement issues identified for grouting the equipment that will be left in Tank 18-F and Tank 19-F. The Tank 18-F and 19-F closure strategy document states that one of the Performance Assessment (PA) requirements for a closed tank is that equipment remaining in the tank be filled to the extent practical and that vertical flow paths 1 inch and larger be grouted. The specific objectives of the Tier 1A equipment grout mock-up testing include: (1) Identifying the most limiting equipment configurations with respect to internal void space filling; (2) Specifying and constructing initial test geometries and forms that represent scaled boundary conditions; (3) Identifying a target grout rheology for evaluation in the scaled mock-up configurations; (4) Scaling-up production of a grout mix with the target rheology

  3. Development of an Acoustic Levitation Linear Transportation System Based on a Ring-Type Structure.

    Thomas, Gilles P L; Andrade, Marco A B; Adamowski, Julio Cezar; Silva, Emilio Carlos Nelli


    A linear acoustic levitation transportation system based on a ring-type vibrator is presented. The system is composed by two 21-kHz Langevin transducers connected to a ring-shaped structure formed by two semicircular sections and two flat plates. In this system, a flexural standing wave is generated along the ring structure, producing an acoustic standing wave between the vibrating ring and a plane reflector located at a distance of approximately a half wavelength from the ring. The acoustic standing wave in air has a series of pressure nodes, where small particles can be levitated and transported. The ring-type transportation system was designed and analyzed by using the finite element method. Additionally, a prototype was built and the acoustic levitation and transport of a small polystyrene particle was demonstrated.

  4. Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation.

    Keun, Hector C; Athersuch, Toby J; Beckonert, Olaf; Wang, Yulan; Saric, Jasmina; Shockcor, John P; Lindon, John C; Wilson, Ian D; Holmes, Elaine; Nicholson, Jeremy K


    We present a novel application of the heteronuclear statistical total correlation spectroscopy (HET-STOCSY) approach utilizing statistical correlation between one-dimensional 19F/1H NMR spectroscopic data sets collected in parallel to study drug metabolism. Parallel one-dimensional (1D) 800 MHz 1H and 753 MHz 19F{1H} spectra (n = 21) were obtained on urine samples collected from volunteers (n = 6) at various intervals up to 24 h after oral dosing with 500 mg of flucloxacillin. A variety of statistical relationships between and within the spectroscopic datasets were explored without significant loss of the typically high 1D spectral resolution, generating 1H-1H STOCSY plots, and novel 19F-1H HET-STOCSY, 19F-19F STOCSY, and 19F-edited 1H-1H STOCSY (X-STOCSY) spectroscopic maps, with a resolution of approximately 0.8 Hz/pt for both nuclei. The efficient statistical editing provided by these methods readily allowed the collection of drug metabolic data and assisted structure elucidation. This approach is of general applicability for studying the metabolism of other fluorine-containing drugs, including important anticancer agents such as 5-fluorouracil and flutamide, and is extendable to any drug metabolism study where there is a spin-active X-nucleus (e.g., 13C, 15N, 31P) label present.

  5. IR spectra of Saturn's ring spokes and multiple shines in the Saturn-rings system

    D'Aversa, Emiliano; Bellucci, Giancarlo; Filacchione, Gianrico; Cerroni, Priscilla; Nicholson, Phil D.; Carrozzo, Filippo G.; Altieri, Francesca; Oliva, Fabrizio; Geminale, Anna; Sindoni, Giuseppe; Hedman, Matthew M.


    During the last Saturn equinox, in 2009 August, spokes on the Saturn's B ring have been observed for the first time spectroscopically, at visible and infrared wavelengths. Measurements were obtained by Cassini-VIMS (Visual and Infrared Mapping Spectrometer) instrument in the 0.35-5.1 micron range. Spokes are either dark or bright features appearing on the B ring straddling the equinoxes, round to elongated in shape, lasting for minutes to hours, and moving partially pushed by Saturn's magnetic field. Previous spokes observations date back to the Voyager (1980 equinox,[1]), followed by a HST campaign (1995 equinox,[2]), and more recently Cassini-ISS images (2009 equinox,[3]). Theoretical models of spoke formation and evolution have been developed based on those observations, but there is not unanimous consensus on them. The most spread model considers the spoke as a cloud of very fine particles electrostatically levitating from the regolith of ring's boulders, and hovering on the ring plane while interacting with the ambient plasma until complete charge neutralization. The process triggering the grain charging is not yet clear (meteoroid bombardment, impacts of Saturn's lightnings electrons, etc.) but in any case a very small grain mass (high charge-to-mass ratio) is needed to allow electrostatic repulsion. From the observational point of view, small grain sizes (0.3-0.5 micron) have been retrieved by modeling the spoke reflectance in the visible spectral range (both Voyager, HST, and Cassini were equipped with multispectral imaging cameras). However, a first VIMS spoke observation ([4]) inferred a more spread size distribution (0.3 to 2.5 microns) to explain the high spoke contrast measured in the infrared. Here we will report about an analysis of two selected sets of spokes observed by VIMS. This selection aimed to include both high and low phase angle observations, and to take advantage from the highest spatial resolution data achieved in the infrared. We will

  6. The magic ring systems thinking approach to control systems

    Mella, Piero


    This book presents a gradual path toward ""educating"" readers in understanding how Control Systems truly operate and in recognizing, simulating and improving them in all fields of activity. Starting from the hypothesis that knowledge of Control Systems is not only a technical fact but also represents a discipline - that is, ""A discipline is a developmental path for acquiring certain skills or competencies. (...) To practice a discipline is to be a lifelong learner. You ""never arrive""; you spend your life mastering disciplines."" (Senge, 2006, p. 10) - Piero Mella has set the objective of m

  7. Equilibrium of a system of superconducting rings in a uniform gravitational field

    Bishaev, A. M.; Bush, A. A.; Gavrikov, M. B.; Gordeev, I. S.; Denisyuk, A. I.; Kamentsev, K. E.; Kozintseva, M. V.; Savel'ev, V. V.; Sigov, A. S.


    To construct a plasma trap with levitating magnetic coils in the thin ring approximation, we derive the expression for the potential energy of a system of several superconducting rings (one of which is fixed) capturing the preset flows in the uniform gravitational field as a function of the coordinates of the free ring (or rings). Calculations performed in the Mathcad system show that the potential energy of such a system has a local minimum for certain values of parameters. Stable levitation of a superconducting ring in the position corresponding to calculations is realized in the field of another superconducting ring, and this leads to the conclusion that a magnetic Galatea trap can be prepared on the basis of a levitating quadrupole.

  8. Tanks 18 And 19-F Structural Flowable Grout Fill Material Evaluation And Recommendations

    Langton, C. A.; Stefanko, D. B.


    Cementitious grout will be used to close Tanks 18-F and 19-F. The functions of the grout are to: 1) physically stabilize the final landfill by filling the empty volume in the tanks with a non-compressible material; 2) provide a barrier for inadvertent intrusion into the tank; 3) reduce contaminant mobility by a) limiting the hydraulic conductivity of the closed tank and b) reducing contact between the residual waste and infiltrating water; and 4) providing an alkaline, chemically reducing environment in the closed tank to control speciation and solubility of selected radionuclides. The objective of this work was to identify a single (all-in-one) grout to stabilize and isolate the residual radionuclides in the tank, provide structural stability of the closed tank and serve as an inadvertent intruder barrier. This work was requested by V. A. Chander, High Level Waste (HLW) Tank Engineering, in HLW-TTR-2011-008. The complete task scope is provided in the Task Technical and QA Plan, SRNL-RP-2011-00587 Revision 0. The specific objectives of this task were to: 1) Identify new admixtures and dosages for formulating a zero bleed flowable tank fill material selected by HLW Tank Closure Project personnel based on earlier tank fill studies performed in 2007. The chemical admixtures used for adjusting the flow properties needed to be updated because the original admixture products are no longer available. Also, the sources of cement and fly ash have changed, and Portland cements currently available contain up to 5 wt. % limestone (calcium carbonate). 2) Prepare and evaluate the placement, compressive strength, and thermal properties of the selected formulation with new admixture dosages. 3) Identify opportunities for improving the mix selected by HLW Closure Project personnel and prepare and evaluate two potentially improved zero bleed flowable fill design concepts; one based on the reactor fill grout and the other based on a shrinkage compensating flowable fill mix design. 4

  9. A 19F NMR study of C-I....pi- halogen bonding

    Hauchecorne, Dieter; vand er Veken, Benjamin J.; Herrebout, Wouter A.


    The formation of halogen bonded complexes between toluene-d8 and the perfluoroiodopropanes 1-C3F7I and 2-C3F7I has been investigated using 19F NMR spectroscopy. For both Lewis acids, evidence was found for the formation of a C–I⋯π halogen bonded complex. The complex formed is a 1:1 type. Using...... spectra recorded at different temperatures, the complexation enthalpies and entropies for the complexes were determined to be −2.9(1) kJ mol−1 and −19.1(2) J K−1 mol−1 for the 2-C3F7I⋅toluene-d8 complex and −2.7(1) kJ mol−1 and −16.0(4) K−1 mol−1 for the 1-C3F7I⋅toluene-d8 complex. The experimental...

  10. An objective reference system for studying rings in the ocean

    Castelão, Guilherme P.; Irber, Luiz C.; Villas Boas, Ana B. M.


    Rings are marine vortices with a scale of hundreds of kilometers that can last for months, whose associated transport and mixing play an important role in the ocean dynamics. Such features are traditionally treated as a geostrophic flow, but since the centrifugal acceleration is not negligible in the inner core, the cyclo-geostrophic balance is a better approximation for the rings. In the present work, we describe a novel objective technique to identify the ring center, which is used as the origin of a convenient framework to handle rings under the cyclo-geostrophic balance. Furthermore, we correct the velocity field by the translation to isolate the swirl movement, a procedure ignored by other methodologies. We show that the lack of such correction would lead to an error of 30 km on the center definition of a ship surveyed North Brazil Current Ring with 160 km of radius. Another distinct characteristic of our approach is the flexibility in the spatio-temporal structure of the data, because it allows for ungridded data, an important ability for in situ observations. That also enables the use of a hybrid dataset composed from different instruments. The error on the Monte Carlo experiments to identify the center of the propagating ring is less than 10 km, and depends on the level of noise, sampling strategy, and strength of the ring, among other factors. This technique was fully implemented in PyRings, an open Python library with a collection of procedures to handle oceanic rings and mesoscale eddies in general.

  11. Conformational selection and functional dynamics of calmodulin: a (19)F nuclear magnetic resonance study.

    Hoang, Joshua; Prosser, R Scott


    Calcium-bound calmodulin (CaM-4Ca(2+)) is innately promiscuous with regard to its protein interaction network within the cell. A key facet of the interaction process involves conformational selection. In the absence of a binding peptide, CaM-4Ca(2+) adopts an equilibrium between a native state (N) and a weakly populated near-native peptide-bound-like state (I), whose lifetime is on the order of 1.5 ms at 37 °C, based on (19)F nuclear magnetic resonance (NMR) Carr-Purcell-Meiboom-Gill (CPMG) relaxation dispersion measurements. This peptide-bound-like state of CaM-4Ca(2+) is entropically stabilized (ΔS = 280 ± 35 J mol(-1) K(-1)) relative to the native state, water-depleted, and likely parental to specific bound states. Solvent depletion, conformational selection, and flexibility of the peptide-bound-like state may be important in priming the protein for binding. At higher temperatures, the exchange rate, kex, appears to markedly slow, suggesting the onset of misfolded or off-pathway states, which retards interconversion between N and I. (19)F NMR CPMG relaxation dispersion experiments with both CaM-4Ca(2+) and the separate N-terminal and C-terminal domains reveal the cooperative role of the two domains in the binding process and the flexibility of the N-terminal domain in facilitating binding. Thus, when calcium binds, calmodulin establishes its interaction with a multitude of protein binding partners, through a combination of conformational selection to a state that is parental to the peptide-bound state and, finally, induced fit.

  12. Ongoing Dynamics and Evolution of Neptune's Ring-Moon System

    Showalter, Mark R.; de Pater, Imke; Lissauer, Jack J.; French, Robert S.


    We report results derived from observations of the Neptune system using the Hubble Space Telescope (HST) during August 2016. These observations entail repeated, extremely long exposures through the broadest available filter on the WFC3/UVIS instrument to reveal details of Neptune's faint rings and small, inner moons. The work complements similar observations performed by HST in 2004-2005 and 2009. A principal goal was the recovery of the small moon S/2004 N 1 (henceforth N14), which was first reported in 2009. New images show the moon clearly and make it possible to obtain accurate orbital elements for the first time. A complete analysis of all data 2004-2016 reveals that the mean motion n = 378.90616 +/- 0.00003 degrees per day, corresponding to a semimajor axis a = 105,283 km. Eccentricity and inclination are quite small, with e < 0.001 and i < 0.1 degrees. (This result accounts for the local Laplace Plane tilt of ~ 0.4 degrees). N14 has a physical radius R = 13-15 km, assuming its albedo is 0.09 +/- 0.01, which is the range of Neptune's other inner moons. It orbits interior to the much larger moon Proteus (a = 117,647 km; R = 210 km). Tides are believed to have caused Proteus to spiral outward significantly since its origin, and we find that N14 orbits within the radial zone likely crossed by Proteus. We suggest that N14 may have originated as debris ejected from an impact into Proteus; Proteus subsequently continued to evolve outward but the debris accreted into N14 and remains at its original point of origin. Naiad, the innermost of Neptune's moons, is now orbiting ~ 120 degrees ahead of its published orbital elements. This represents only a 1-sigma correction from its mean motion as derived from Voyager data, but it indicates that later, purported detections of Naiad with the Keck telescope were almost certainly misidentifications. The arcs in the Adams ring show that trends reported previously have continued: the two leading arcs are no longer visible

  13. Dynamical systems analysis of fluid transport in time-periodic vortex ring flows

    Shariff, Karim; Leonard, Anthony; Ferziger, Joel H.


    It is known that the stable and unstable manifolds of dynamical systems theory provide a powerful tool for understanding Lagrangian aspects of time-periodic flows. In this work we consider two time-periodic vortex ring flows. The first is a vortex ring with an elliptical core. The manifolds provide information about entrainment and detrainment of irrotational fluid into and out of the volume transported with the ring. The likeness of the manifolds with features observed in flow visualization ...

  14. Multinucleon transfer in O,1816,19F+208Pb reactions at energies near the fusion barrier

    Rafferty, D. C.; Dasgupta, M.; Hinde, D. J.; Simenel, C.; Simpson, E. C.; Williams, E.; Carter, I. P.; Cook, K. J.; Luong, D. H.; McNeil, S. D.; Ramachandran, K.; Vo-Phuoc, K.; Wakhle, A.


    Background: Nuclear reactions are complex, involving collisions between composite systems where many-body dynamics determines outcomes. Successful models have been developed to explain particular reaction outcomes in distinct energy and mass regimes, but a unifying picture remains elusive. The irreversible transfer of kinetic energy from the relative motion of the collision partners to their internal states, as is known to occur in deep inelastic collisions, has yet to be successfully incorporated explicitly into fully quantal reaction models. The influence of these processes on fusion is not yet quantitatively understood. Purpose: To investigate the population of high excitation energies in transfer reactions at sub-barrier energies, which are precursors to deep inelastic processes, and their dependence on the internuclear separation. Methods: Transfer probabilities and excitation energy spectra have been measured in collisions of O,1816,19F+208Pb , at various energies below and around the fusion barrier, by detecting the backscattered projectile-like fragments in a Δ E -E telescope. Results: The relative yields of different transfer outcomes are strongly driven by Q values, but change with the internuclear separation. In 16O+208Pb , single nucleon transfer dominates, with a strong contribution from -2 p transfer close to the Coulomb barrier, though this channel becomes less significant in relation to the -2 p 2 n transfer channel at larger separations. For 18O+208Pb , the -2 p 2 n channel is the dominant charge transfer mode at all separations. In the reactions with 19F,-3 p 2 n transfer is significant close to the barrier, but falls off rapidly with energy. Multinucleon transfer processes are shown to lead to high excitation energies (up to ˜15 MeV), which is distinct from single nucleon transfer modes which predominantly populate states at low excitation energy. Conclusions: Kinetic energy is transferred into internal excitations following transfer, with this

  15. Direct Comparison of 19F qNMR and 1H qNMR by Characterizing Atorvastatin Calcium Content

    Yang Liu


    Full Text Available Quantitative nuclear magnetic resonance (qNMR is a powerful tool in measuring drug content because of its high speed, sensitivity, and precision. Most of the reports were based on proton qNMR (1H qNMR and only a few fluorine qNMR (19F qNMR were reported. No research has been conducted to directly compare the advantage and disadvantage between these two methods. In the present study, both 19F and 1H qNMR were performed to characterize the content of atorvastatin calcium with the same internal standard. Linearity, precision, and results from two methods were compared. Results showed that 19F qNMR has similar precision and sensitivity to 1H qNMR. Both methods generate similar results compared to mass balance method. Major advantage from 19F qNMR is that the analyte signal is with less or no interference from impurities. 19F qNMR is an excellent approach to quantify fluorine-containing analytes.

  16. Highly efficient (19)F heteronuclear decoupling in solid-state NMR spectroscopy using supercycled refocused-CW irradiation.

    Equbal, Asif; Basse, Kristoffer; Nielsen, Niels Chr


    We present heteronuclear (19)F refocused CW (rCW) decoupling pulse sequences for solid-state magic-angle-spinning NMR applications. The decoupling sequences have been designed specifically to ensure suppression of the pertinent (13)C-(19)F dipolar coupling interactions while simultaneously suppressing strong anisotropic chemical shift as well as homonuclear (19)F-(19)F dipolar coupling effects as typically present in perfluorated compounds. In an extensive numerical and experimental analysis using a rigid, organic solid as a model compound, it becomes evident that the supercycled rCW schemes markedly improve the decoupling efficiency, leading to substantial enhancements in resolution and sensitivity when compared to previous state-of-the-art methods. Furthermore, considerable gains in robustness toward rf mismatch as well as offset in the radio-frequency carrier frequency are observed, all of which clearly render the new rCW schemes the methods of choice for (19)F decoupling in rigid, fluorinated compounds - which is further supported by a Floquet-based theoretical analysis.

  17. Multiple internal seal ring micro-electro-mechanical system vacuum packaging method

    Hayworth, Ken J. (Inventor); Yee, Karl Y. (Inventor); Shcheglov, Kirill V. (Inventor); Bae, Youngsam (Inventor); Wiberg, Dean V. (Inventor); Challoner, A. Dorian (Inventor); Peay, Chris S. (Inventor)


    A Multiple Internal Seal Ring (MISR) Micro-Electro-Mechanical System (MEMS) vacuum packaging method that hermetically seals MEMS devices using MISR. The method bonds a capping plate having metal seal rings to a base plate having metal seal rings by wafer bonding the capping plate wafer to the base plate wafer. Bulk electrodes may be used to provide conductive paths between the seal rings on the base plate and the capping plate. All seals are made using only metal-to-metal seal rings deposited on the polished surfaces of the base plate and capping plate wafers. However, multiple electrical feed-through metal traces are provided by fabricating via holes through the capping plate for electrical connection from the outside of the package through the via-holes to the inside of the package. Each metal seal ring serves the dual purposes of hermetic sealing and providing the electrical feed-through metal trace.

  18. A nanoelectromechanical systems actuator driven and controlled by Q-factor attenuation of ring resonator

    Dong, B.; Cai, H.; Ng, G. I.; Kropelnicki, P.; Tsai, J. M.; Randles, A. B.; Tang, M.; Gu, Y. D.; Suo, Z. G.; Liu, A. Q.


    In this Letter, an optical gradient force driven Nanoelectromechanical Systems (NEMS) actuator, which is controlled by the Q-factor attenuation of micro-ring resonator, is demonstrated. The actuator consists of a tunable actuation ring resonator, a sensing ring resonator, and a mechanical actuation arc. The actuation displacement can reach up to 14 nm with a measured resolution of 0.8 nm, when the Q-factor of the ring resonator is tuned from 15 × 103 to 6 × 103. The potential applications of the NEMS actuator include single molecule manipulation, nano-manipulation, and high sensitivity sensors.

  19. Saturn's Rings

    Cuzzi, J. N.


    The rings are changing before our eyes; structure varies on all timescales and unexpected things have been discovered. Many questions have been answered, but some answers remain elusive (see Cuzzi et al 2010 for a review). Here we highlight the major ring science progress over the mission to date, and describe new observations planned for Cassini's final three years. Ring Composition and particle sizes: The rings are nearly all water ice with no other ices - so why are they reddish? The C Ring and Cassini Division are "dirtier" than the more massive B and A Rings, as shown by near-IR and, recently, microwave observations. Particle sizes, from stellar and radio occultations, vary from place to place. Ring structure, micro and macro: numerous spiral density waves and ubiquitous "self-gravity wakes" reveal processes which fostered planet formation in the solar system and elsewhere. However, big puzzles remain regarding the main ring divisions, the C Ring plateau structures, and the B Ring irregular structure. Moonlets, inside and out, seen and unseen: Two gaps contain sizeable moonlets, but more gaps seem to contain none; even smaller embedded "propeller" objects wander, systematically or randomly, through the A ring. Rubble pile ringmoons just outside the rings may escaped from the rings, and the recently discovered "Peggy" may be trying this as we watch. Impact bombardment of the rings: Comet fragments set the rings to rippling on century-timescales, and boulders crash through hourly; meanwhile, the constant hail of infalling Kuiper belt material has a lower mass flux than previously thought. Origin and Age of the Rings: The ring mass and bombardment play key roles. The ring mass is well known everywhere but in the B Ring (where most of it is). New models suggest how tidal breakup of evolving moons may have formed massive ancient rings, of which the current ring is just a shadow. During its last three years, the Cassini tour profile will allow entirely new


    Stefanko, D.; Langton, C.


    Cementitious grout will be used to close Tanks 18-F and 19-F. The functions of the grout are to: (1) physically stabilize the final landfill by filling the empty volume in the tanks with a non compressible material; (2) provide a barrier for inadvertent intrusion into the tank; (3) reduce contaminant mobility by (a) limiting the hydraulic conductivity of the closed tank and (b) reducing contact between the residual waste and infiltrating water; and (4) providing an alkaline, chemically reducing environment in the closed tank to control speciation and solubility of selected radionuclides. The objective of this work was to identify a single (all-in-one) grout to stabilize and isolate the residual radionuclides in the tank, provide structural stability of the closed tank and serve as an inadvertent intruder barrier. This work was requested by V. A. Chander, High Level Waste (HLW) Tank Engineering, in HLW-TTR-2011-008. The complete task scope is provided in the Task Technical and QA Plan, SRNL-RP-2011-00587 Revision 0. The specific objectives of this task were to: (1) Identify new admixtures and dosages for formulating a zero bleed flowable tank fill material selected by HLW Tank Closure Project personnel based on earlier tank fill studies performed in 2007. The chemical admixtures used for adjusting the flow properties needed to be updated because the original admixture products are no longer available. Also, the sources of cement and fly ash have changed, and Portland cements currently available contain up to 5 wt. % limestone (calcium carbonate). (2) Prepare and evaluate the placement, compressive strength, and thermal properties of the selected formulation with new admixture dosages. (3) Identify opportunities for improving the mix selected by HLW Closure Project personnel and prepare and evaluate two potentially improved zero bleed flowable fill design concepts; one based on the reactor fill grout and the other based on a shrinkage compensating flowable fill mix

  1. A complete infrared Einstein ring in the gravitational lens system B1938+666

    King, LJ; Jackson, N; Blandford, RD; Browne, IWA; de Bruyn, AG; Fassnacht, C; Koopmans, L; Marlow, D; Wilkinson, PN


    We report the discovery, using NICMOS on the Hubble Space Telescope, of an arcsec-diameter Einstein ring in the gravitational lens system B1938 + 666. The lensing galaxy is also detected, and is most likely an early-type galaxy. Modelling of the ring is presented and compared with the radio structur

  2. Gaseous toroid around Saturn. [Saturnian ring system for atomic hydrogen trapping in Titan atmospheric model

    Mcdonough, T. R.


    The trapping of Titan's escaping atmosphere in the Saturnian system by a toroidal ring is discussed. The radius of the toroid is comparable to Titan's orbit, or about ten times larger than the visible rings. Theoretical atmospheric models are formulated that consider Saturn's gravitational attraction and magnetospheric properties in forming this toroid and in protecting toroid particles from direct ionization by solar wind particles.

  3. Evidence of a structural phase transition in superconducting SmFeAsO1-xFx from 19F NMR

    Majumder, M.; Ghoshray, K.; Mazumdar, C.; Poddar, A.; Ghoshray, A.; Berardan, D.; Dragoe, N.


    We report resistivity, magnetization and 19F NMR results in a polycrystalline sample of SmFeAsO0.86F0.14. The resistivity and magnetization data show a sharp drop at 48 K indicating a superconducting transition. The nuclear spin-lattice rate (1/T1) and spin-spin relaxation rate (1/T2) clearly show the existence of a structural phase transition near 163 K in the sample, which also undergoes a superconducting transition. This finding creates interest in exploring whether this is unique for Sm based systems or is also present in other rare-earth based 1111 superconductors.

  4. Robust and efficient 19F heteronuclear dipolar decoupling using refocused continuous-wave rf irradiation

    Vinther, Joachim M.; Khaneja, Navin; Nielsen, Niels Chr.


    Refocused continuous wave (rCW) decoupling is presented as an efficient and robust means to obtain well-resolved magic-angle-spinning solid-state NMR spectra of low-γ spins, such as 13C dipolar coupled to fluorine. The rCW decoupling sequences, recently introduced for 1H decoupling, are very robust towards large isotropic and anisotropic shift ranges as often encountered for 19F spins. In rCW decoupling, the so-called refocusing pulses inserted into the CW irradiation eliminate critical residual second- and third-order dipolar coupling and dipolar-coupling against chemical shielding anisotropy cross-terms in the effective Hamiltonian through time-reversal (i.e. refocusing). As important additional assets, the rCW decoupling sequences are robust towards variations in rf amplitudes, operational at low to high spinning speeds, and easy to set-up for optimal performance experimentally. These aspects are demonstrated analytically/numerically and experimentally in comparison to state-of-the-art decoupling sequences such as TPPM, SPINAL-64, and frequency-swept variants of these.

  5. Determination of {sup 19} F - {sup 13} C coupling constants and their use in mono fluoro benzaldehyde derivatives conformational analysis

    Villar, Jose Daniel Figueroa [Instituto Militar de Engenharia (IME), Rio de Janeiro, RJ (Brazil). Inst. de Quimica


    The element fluorine is extremely important in medicinal chemistry. In order to research the possible molecular alterations introduced for the substitution of hydrogen for fluorine, the study of {sup 19} F-{sup 13} C coupling constants is necessary. In this work, ortho- and para-fluorine-substituted benzaldehydes and some other aromatic fluoro compounds were studied using {sup 1} H, {sup 13} C and {sup 19} F NMR. The long range C-F coupling constants were measured from the PND spectra and compared with the long range values of H-C coupling constants, so as to, at first, determine their importance in conformational analysis 5 refs., 2 figs., 3 tabs.

  6. Mobility Impact in Initializing Ring-Based P2P Systems over MANETs

    Wei Ding


    Full Text Available With the encouragement from success of P2P systems in real world application, recently we have seen active research on synergy of P2P systems and mobile ad hoc networks. The paper proposes a solution for mobility disturbance problem in initialization of ring-based P2P systems over ad hoc networks. It is a decentralized ring construction protocol in presence of mobility. A Mobile Ring Ad-hoc Networks (MRAN protocol is presented. MRAN is an extension of RAN [1] under the mobile condition. Simulation result shows MRAN works well with mobility. Upper bound of maximum speed of moving nodes is investigated in simulation.

  7. Assessment of chemical exchange in tryptophan–albumin solution through {sup 19}F multicomponent transverse relaxation dispersion analysis

    Lin, Ping-Chang, E-mail: [Howard University, Department of Radiology, College of Medicine (United States)


    A number of NMR methods possess the capability of probing chemical exchange dynamics in solution. However, certain drawbacks limit the applications of these NMR approaches, particularly, to a complex system. Here, we propose a procedure that integrates the regularized nonnegative least squares (NNLS) analysis of multiexponential T{sub 2} relaxation into Carr–Purcell–Meiboom–Gill (CPMG) relaxation dispersion experiments to probe chemical exchange in a multicompartmental system. The proposed procedure was validated through analysis of {sup 19}F T{sub 2} relaxation data of 6-fluoro-DL-tryptophan in a two-compartment solution with and without bovine serum albumin. Given the regularized NNLS analysis of a T{sub 2} relaxation curve acquired, for example, at the CPMG frequency υ{sub CPMG} = 125, the nature of two distinct peaks in the associated T{sub 2} distribution spectrum indicated 6-fluoro-DL-tryptophan either retaining the free state, with geometric mean */multiplicative standard deviation (MSD) = 1851.2 ms */1.51, or undergoing free/albumin-bound interconversion, with geometric mean */MSD = 236.8 ms */1.54, in the two-compartment system. Quantities of the individual tryptophan species were accurately reflected by the associated T{sub 2} peak areas, with an interconversion state-to-free state ratio of 0.45 ± 0.11. Furthermore, the CPMG relaxation dispersion analysis estimated the exchange rate between the free and albumin-bound states in this fluorinated tryptophan analog and the corresponding dissociation constant of the fluorinated tryptophan–albumin complex in the chemical-exchanging, two-compartment system.

  8. (19)F(α,n) thick target yield from 3.5 to 10.0 MeV.

    Norman, E B; Chupp, T E; Lesko, K T; Grant, P J; Woodruff, G L


    Using a target of PbF2, the thick-target yield from the (19)F(α,n) reaction was measured from E(α)=3.5-10 MeV. From these results, we infer the thick-target neutron yields from targets of F2 and UF6 over this same alpha-particle energy range.

  9. Angular Distribution and Angular Dispersion in Collision of 19F+27A1 at 114 MeV

    WANG Qi; Li Zhi-Chang; LU Xiu-Qin; ZHAO Kui; LIU Jian-Cheng; SERGEY Yu-Kun; DONG Yu-Chuan; LI Song-Lin; DUAN Li-Min; XU Hu-Shan; XU Hua-Gen; CHEN Ruo-Fu; WU He-Yu; HAN Jian-Long


    Angular distributions of fragments B, C, N, O, F, Ne, Na, Mg and Al induced by the collision of 19F+27 A1 at 114MeV have been measured. Angular dispersion parameters are extracted from the experimental data and compared with the theoretical ones. The dynamic dispersions for dissipative products depend strongly on the charge number Z of the fragments.

  10. Optimization of localized 19F magnetic resonance spectroscopy for the detection of fluorinated drugs in the human liver.

    Klomp, D.W.J.; Laarhoven, H.W.M. van; Kentgens, A.P.M.; Heerschap, A.


    Fluorine MR spectroscopy ((19)F MRS) is an indispensable tool for assessing the pharmacokinetics of fluorinated drugs. Since the metabolism of 5-fluorouracil (5FU), a frequently used cytotoxic drug, is expected to be different in normal liver and in tumor tissue, spatial localization is required for

  11. (19)F-heptuloses as tools for the non-invasive imaging of GLUT2-expressing cells

    Malaisse, Willy J; Zhang, Ying; Louchami, Karim


    Suitable analogs of d-mannoheptulose are currently considered as possible tools for the non-invasive imaging of pancreatic islet insulin-producing cells. Here, we examined whether (19)F-heptuloses could be used for non-invasive imaging of GLUT2-expressing cells. After 20 min incubation, the uptake...

  12. Domino Wittig Diels-Alder reaction: An expeditious entry into the AB ring system of furanosesquiterpenes

    Patre, R.E.; Gawas, S.; Sen, S.; Parameswaran, P.S.; Tilve, S.G.

    A domino Wittig Diels - Alder reaction has been employed in delineating a short and flexible synthetic stratagem for ready access to the AB ring system and the tricyclic framework of furanosesquiterpenes, such as the bioactive natural products...

  13. Synthesis of fused indazole ring systems and application to nigeglanine hydrobromide.

    Sather, Aaron C; Berryman, Orion B; Rebek, Julius


    The single-step synthesis of fused tricyclic pyridazino[1,2-a]indazolium ring systems is described. Structural details revealed by crystallography explain the unexpected reactivity. The method is applied to the gram scale synthesis of nigeglanine hydrobromide.

  14. Planetary Rings

    Tiscareno, Matthew S


    Planetary rings are the only nearby astrophysical disks, and the only disks that have been investigated by spacecraft. Although there are significant differences between rings and other disks, chiefly the large planet/ring mass ratio that greatly enhances the flatness of rings (aspect ratios as small as 1e-7), understanding of disks in general can be enhanced by understanding the dynamical processes observed at close-range and in real-time in planetary rings. We review the known ring systems of the four giant planets, as well as the prospects for ring systems yet to be discovered. We then review planetary rings by type. The main rings of Saturn comprise our system's only dense broad disk and host many phenomena of general application to disks including spiral waves, gap formation, self-gravity wakes, viscous overstability and normal modes, impact clouds, and orbital evolution of embedded moons. Dense narrow rings are the primary natural laboratory for understanding shepherding and self-stability. Narrow dusty...

  15. {sup 19}F-labeling of the adenine H2-site to study large RNAs by NMR spectroscopy

    Sochor, F. [Johann Wolfgang Goethe-University Frankfurt, Institut für Organische Chemie und Chemische Biologie, Center for Biomolecular Magnetic Resonance (BMRZ) (Germany); Silvers, R. [Massachusetts Institute of Technology, Department of Chemistry, Francis Bitter Magnet Laboratory (United States); Müller, D.; Richter, C.; Fürtig, B., E-mail:; Schwalbe, H., E-mail: [Johann Wolfgang Goethe-University Frankfurt, Institut für Organische Chemie und Chemische Biologie, Center for Biomolecular Magnetic Resonance (BMRZ) (Germany)


    In comparison to proteins and protein complexes, the size of RNA amenable to NMR studies is limited despite the development of new isotopic labeling strategies including deuteration and ligation of differentially labeled RNAs. Due to the restricted chemical shift dispersion in only four different nucleotides spectral resolution remains limited in larger RNAs. Labeling RNAs with the NMR-active nucleus {sup 19}F has previously been introduced for small RNAs up to 40 nucleotides (nt). In the presented work, we study the natural occurring RNA aptamer domain of the guanine-sensing riboswitch comprising 73 nucleotides from Bacillus subtilis. The work includes protocols for improved in vitro transcription of 2-fluoroadenosine-5′-triphosphat (2F-ATP) using the mutant P266L of the T7 RNA polymerase. Our NMR analysis shows that the secondary and tertiary structure of the riboswitch is fully maintained and that the specific binding of the cognate ligand hypoxanthine is not impaired by the introduction of the {sup 19}F isotope. The thermal stability of the {sup 19}F-labeled riboswitch is not altered compared to the unmodified sequence, but local base pair stabilities, as measured by hydrogen exchange experiments, are modulated. The characteristic change in the chemical shift of the imino resonances detected in a {sup 1}H,{sup 15}N-HSQC allow the identification of Watson–Crick base paired uridine signals and the {sup 19}F resonances can be used as reporters for tertiary and secondary structure transitions, confirming the potential of {sup 19}F-labeling even for sizeable RNAs in the range of 70 nucleotides.

  16. First Measurement of the 19F(α, p)22Ne Reaction at Energies of Astrophysical Relevance

    Pizzone, R. G.; D’Agata, G.; La Cognata, M.; Indelicato, I.; Spitaleri, C.; Blagus, S.; Cherubini, S.; Figuera, P.; Grassi, L.; Guardo, G. L.; Gulino, M.; Hayakawa, S.; Kshetri, R.; Lamia, L.; Lattuada, M.; Mijatović, T.; Milin, M.; Miljanić D., Đ.; Prepolec, L.; Rapisarda, G. G.; Romano, S.; Sergi, M. L.; Skukan, N.; Soić, N.; Tokić, V.; Tumino, A.; Uroić, M.


    The observational 19F abundance in stellar environments systematically exceeds the predicted one, thus representing one of the unsolved challenges for stellar modeling. It is therefore clear that further investigation is needed in this field. In this work, we focus our attention on the measurement of the {}19{{F}}{(α ,p)}22{Ne} reaction in the astrophysical energy range, between 0.2 and 0.8 MeV (far below the Coulomb barrier, 3.8 MeV), as it represents the main destruction channel in He-rich environments. The lowest energy at which this reaction has been studied with direct measurements is ∼0.66 MeV, covering only the upper tail of the Gamow window, causing the reaction-rate evaluation to be based on extrapolation. To investigate lower energies, the {}19{{F}}{(α ,p)}22{Ne} reaction has been studied by means of the Trojan horse method, applied to the quasi-free {}6{Li}{{(}19{{F}},{p}22{Ne})}2{{H}} reaction at E beam = 6 MeV. The indirect cross section of the {}19{{F}}{(α ,p)}22{Ne} reaction at energies ≲1 MeV was extracted, fully covering the astrophysical region of interest and overlapping existing direct data for normalization. Several resonances have been detected for the first time inside the Gamow window. The reaction rate has been calculated, showing an increase up to a factor of 4 with respect to the literature at astrophysical temperatures. This might lead to potential major astrophysical implications.

  17. In-Vivo Detection and Tracking of T Cells in Various Organs in a Melanoma Tumor Model by 19F-Fluorine MRS/MRI

    Gonzales, Christine; Yoshihara, Hikari A. I.; Dilek, Nahzli; Leignadier, Julie; Irving, Melita; Mieville, Pascal; Helm, Lothar; Michielin, Olivier; Schwitter, Juerg


    Background 19F-MRI and 19F-MRS can identify specific cell types after in-vitro or in-vivo 19F-labeling. Knowledge on the potential to track in-vitro 19F-labeled immune cells in tumor models by 19F-MRI/MRS is scarce. Aim To study 19F-based MR techniques for in-vivo tracking of adoptively transferred immune cells after in-vitro 19F-labeling, i.e. to detect and monitor their migration non-invasively in melanoma-bearing mice. Methods Splenocytes (SP) were labeled in-vitro with a perfluorocarbon (PFC) and IV-injected into non-tumor bearing mice. In-vitro PFC-labeled ovalbumin (OVA)-specific T cells from the T cell receptor-transgenic line OT-1, activated with anti-CD3 and anti-CD28 antibodies (Tact) or OVA-peptide pulsed antigen presenting cells (TOVA-act), were injected into B16 OVA melanoma-bearing mice. The distribution of the 19F-labelled donor cells was determined in-vivo by 19F-MRI/MRS. In-vivo 19F-MRI/MRS results were confirmed by ex-vivo 19F-NMR and flow cytometry. Results SP, Tact, and TOVA-act were successfully PFC-labeled in-vitro yielding 3x1011-1.4x1012 19F-atoms/cell in the 3 groups. Adoptively transferred 19F-labeled SP, TOVA-act, and Tact were detected by coil-localized 19F-MRS in the chest, abdomen, and left flank in most animals (corresponding to lungs, livers, and spleens, respectively, with highest signal-to-noise for SP vs TOVA-act and Tact, p<0.009 for both). SP and Tact were successfully imaged by 19F-MRI (n = 3; liver). These in-vivo data were confirmed by ex-vivo high-resolution 19F-NMR-spectroscopy. By flow cytometric analysis, however, TOVA-act tended to be more abundant versus SP and Tact (liver: p = 0.1313; lungs: p = 0.1073; spleen: p = 0.109). Unlike 19F-MRI/MRS, flow cytometry also identified transferred immune cells (SP, Tact, and TOVA-act) in the tumors. Conclusion SP, Tact, and TOVA-act were successfully PFC-labeled in-vitro and detected in-vivo by non-invasive 19F-MRS/MRI in liver, lung, and spleen. The portion of 19F-labeled T cells

  18. Hardware Design of Wireless Physical Token Ring System for Mobile and Cell Communication

    Nidal F. Shilbayeh


    Full Text Available A wireless network system based on an infrared and Laser scanning Physical Token Ring architecture (W-PTRS was designed, built and tested successfully. The network provides a different way of utilizing the concept of a token ring network but with a higher efficiency related to the speed of data transfer and the ability to parallel process client-server requests leading to a new concept of the token ring system, which will not fail simply because of ring breakage. The study proposes a new wireless communication protocol, which is neither IEEE802.11 nor Bluetooth. This newly developed protocol could prove to be an excellent communication media if supported by industry. If implemented, this wireless system will provide an alternative but efficient way of wireless communication.

  19. Using Ring Laser Systems to Measure Gravitomagnetic Effects on Earth

    Ruggiero, Matteo Luca


    Gravitomagnetic effects originates from the rotation of the source of the gravitational field and from the rotational features of the observers' frame. In recent years, gravitomagnetism has been tested by means of its impact on the precession of LAGEOS orbits and on the precession of spherical gyroscopes in the GP-B experiment. What we suggest here is that light can be used as a probe to test gravitomagnetic effects in an terrestrial laboratory: the proposed detector consists of large ring-lasers arranged along three orthogonal axes.

  20. Dragging of inertial frames in the composed black-hole–ring system

    Hod, Shahar, E-mail: [The Ruppin Academic Center, 40250, Emeq Hefer (Israel); The Hadassah Institute, 91010, Jerusalem (Israel)


    A well-established phenomenon in general relativity is the dragging of inertial frames by a spinning object. In particular, due to the dragging of inertial frames by a ring orbiting a central black hole, the angular velocity Ω{sub H}{sup BH-ring} of the black-hole horizon in the composed black-hole–ring system is no longer related to the black-hole angular momentum J{sub H} by the simple Kerr-like (vacuum) relation Ω{sub H}{sup Kerr}(J{sub H})=J{sub H}/2M{sup 2}R{sub H} (here M and R{sub H} are the mass and horizon-radius of the black hole, respectively). Will has performed a perturbative treatment of the composed black-hole–ring system in the regime of slowly rotating black holes and found the explicit relation Ω{sub H}{sup BH-ring}(J{sub H}=0,J{sub R},R)=2J{sub R}/R{sup 3} for the angular velocity of a central black hole with zero angular momentum, where J{sub R} and R are respectively the angular momentum of the orbiting ring and its proper circumferential radius. Analyzing a sequence of black-hole–ring configurations with adiabatically varying (decreasing) circumferential radii, we show that the expression found by Will for Ω{sub H}{sup BH-ring}(J{sub H}=0,J{sub R},R) implies a smooth transition of the central black-hole angular velocity from its asymptotic near-horizon value Ω{sub H}{sup BH-ring}(J{sub H}=0,J{sub R},R→R{sub H}{sup +})→2J{sub R}/R{sub H}{sup 3} (that is, just before the assimilation of the ring by the central black hole), to its final Kerr (vacuum) value Ω{sub H}{sup Kerr}(J{sub H}{sup new})=J{sub H}{sup new}/2M{sup new2}R{sub H}{sup new} [that is, after the adiabatic assimilation of the ring by the central black hole. Here J{sub H}{sup new}=J{sub R}, M{sup new}, and R{sub H}{sup new} are the new parameters of the resulting Kerr (vacuum) black hole after it assimilated the orbiting ring]. We use this important observation in order to generalize the result of Will to the regime of black-hole–ring configurations in which the

  1. Dragging of inertial frames in the composed black-hole-ring system

    Hod, Shahar [The Ruppin Academic Center, Emeq Hefer (Israel); The Hadassah Institute, Jerusalem (Israel)


    A well-established phenomenon in general relativity is the dragging of inertial frames by a spinning object. In particular, due to the dragging of inertial frames by a ring orbiting a central black hole, the angular velocity Ω{sub H}{sup BH-ring} of the black-hole horizon in the composed black-hole-ring system is no longer related to the black-hole angular momentum J{sub H} by the simple Kerr-like (vacuum) relation Ω{sub H}{sup Kerr}(J{sub H}) = J{sub H}/2M{sup 2}R{sub H} (here M and R{sub H} are the mass and horizon-radius of the black hole, respectively). Will has performed a perturbative treatment of the composed black-hole-ring system in the regime of slowly rotating black holes and found the explicit relation Ω{sub H}{sup BH-ring}(J{sub H} = 0, J{sub R}, R) = 2J{sub R}/R{sup 3} for the angular velocity of a central black hole with zero angular momentum, where J{sub R} and R are respectively the angular momentum of the orbiting ring and its proper circumferential radius. Analyzing a sequence of black-hole-ring configurations with adiabatically varying (decreasing) circumferential radii, we show that the expression found by Will for Ω{sub H}{sup BH-ring}(J{sub H} = 0, J{sub R}, R) implies a smooth transition of the central black-hole angular velocity from its asymptotic near-horizon value Ω{sub H}{sup BH-ring}(J{sub H} = 0, J{sub R}, R → R{sub H}{sup +}) → 2J{sub R}/R{sub H}{sup 3} (that is, just before the assimilation of the ring by the central black hole), to its final Kerr (vacuum) value Ω{sub H}{sup Kerr}(J{sub H}{sup new})= J{sub H}{sup new}/2M{sup new2}R{sub H}{sup new} [that is, after the adiabatic assimilation of the ring by the central black hole. Here J{sub H}{sup new} = J{sub R}, M{sup new}, and R{sub H}{sup new} are the new parameters of the resulting Kerr (vacuum) black hole after it assimilated the orbiting ring]. We use this important observation in order to generalize the result of Will to the regime of black-hole-ring configurations

  2. Dynamical systems analysis of fluid transport in time-periodic vortex ring flows

    Shariff, Karim; Leonard, Anthony; Ferziger, Joel H.


    It is known that the stable and unstable manifolds of dynamical systems theory provide a powerful tool for understanding Lagrangian aspects of time-periodic flows. In this work we consider two time-periodic vortex ring flows. The first is a vortex ring with an elliptical core. The manifolds provide information about entrainment and detrainment of irrotational fluid into and out of the volume transported with the ring. The likeness of the manifolds with features observed in flow visualization experiments of turbulent vortex rings suggests that a similar process might be at play. However, what precise modes of unsteadiness are responsible for stirring in a turbulent vortex ring is left as an open question. The second situation is that of two leapfrogging rings. The unstable manifold shows striking agreement with even the fine features of smoke visualization photographs, suggesting that fluid elements in the vicinity of the manifold are drawn out along it and begin to reveal its structure. We suggest that interpretations of these photographs that argue for complex vorticity dynamics ought to be reconsidered. Recently, theoretical and computational tools have been developed to locate structures analogous to stable and unstable manifolds in aperiodic, or finite-time systems. The usefulness of these analogs is demonstrated, using vortex ring flows as an example, in the paper by Shadden, Dabiri, and Marsden [Phys. Fluids 18, 047105 (2006)].

  3. CF3 Rotation in 3-(Trifluoromethyl)phenanthrene: Solid State 19F and 1H NMR relaxation and Bloch-Wangsness-Redfield theory.

    Beckmann, Peter A; Rosenberg, Jessie; Nordstrom, Kerstin; Mallory, Clelia W; Mallory, Frank B


    We have observed and modeled the 1H and 19F solid-state nuclear spin relaxation process in polycrystalline 3-(trifluoromethyl)phenanthrene. The relaxation rates for the two spin species were observed from 85 to 300 K at the low NMR frequencies of omega/2pi = 22.5 and 53.0 MHz where CF3 rotation, characterized by a mean time tau between hops, is the only motion on the NMR time scale. All motional time scales (omegatau 1) are observed. The 1H spins are immobile on the NMR time scale but are coupled to the 19F spins via the unlike-spin dipole-dipole interaction. The temperature dependence of the observed relaxation rates (the relaxation is biexponential) shows considerable structure and a thorough analysis of Bloch-Wangsness-Redfield theory for this coupled spin system is provided. The activation energy for CF3 rotation is 11.5 +/- 0.7 kJ/mol, in excellent agreement with the calculation in a 13-molecule cluster provided in the companion paper where the crystal structure is reported and detailed ab initio electronic structure calculations are performed [Wang, X.; Mallory F. B.; Mallory, C. W; Beckmann, P. A.; Rheingold, A. L.; Francl, M. M J. Phys. Chem. A 2006, 110, 3954].

  4. Solar system history as recorded in the Saturnian ring structure

    Alfven, H.


    Holberg's analysis of the Voyager Saturn photographs in reflected and transparent light, and occultation data of stars seen through the rings are discussed. A hyperfine structure, with 10,000 ringlets can be explained by the Baxter-Thompson negative diffusion. This gives the ringlets a stability which makes it possible to interpret them as fossils, which originated at cosmogonic times. It is shown that the bulk structure can be explained by the combined cosmogonic shadows of the satellites Mimas, Janus and the Shepherd satellites. This structure originated at the transition from the plasma phase to the planetesimal phase. The shadows are not simple void regions but exhibit a characteristic signature. Parts of the fine structure, explained by Holberg as resonances with satellites, are interpreted as cosmogonic shadow effects. However, there are a number of ringlets which can neither be explained by cosmogonic nor by resonance effects. Analysis of ring data can reconstruct the plasma-planetesimal transition with an accuracy of a few percent.

  5. Transit Model of Planets with Moon and Ring System

    Tusnski, Luis Ricardo M; 10.1088/0004-637X/743/1/97


    Since the discovery of the first exoplanets, those most adequate for life to begin and evolve have been sought. Due to observational bias, however, most of the discovered planets so far are gas giants, precluding their habitability. However, if these hot Jupiters are located in the habitable zones of their host stars, and if rocky moons orbit them, then these moons may be habitable. In this work, we present a model for planetary transit simulation considering the presence of moons and planetary rings around a planet. The moon's orbit is considered to be circular and coplanar with the planetary orbit. The other physical and orbital parameters of the star, planet, moon, and rings can be adjusted in each simulation. It is possible to simulate as many successive transits as desired. Since the presence of spots on the surface of the star may produce a signal similar to that of the presence of a moon, our model also allows for the inclusion of starspots. The result of the simulation is a light curve with a planetar...




    BNL is undertaking the design, construction and commissioning of the Spallation Neutron Source (SNS) accumulator ring and the beam transport lines [l]. Ultrahigh vacuum of 10{sup {minus}9} Torr is required in the accumulator ring to minimize beam-gas ionization, a contributing factor to the e-p instability observed in a few high-intensity proton storage rings. All vacuum instrumentation must be capable of local and remote operation to achieve a reliable vacuum system, especially in this extremely high intensity accelerator. The design and development of the SNS ring vacuum instrumentation and control through the Experimental Physics and Industrial Control System (EPICS) distributed real-time software tools are presented.

  7. Planetary Rings

    Cuzzi, Jeffrey N.


    Just over two decades ago, Jim Pollack made a critical contribution to our understanding of planetary ring particle properties, and resolved a major apparent paradox between radar reflection and radio emission observations. At the time, particle properties were about all there were to study about planetary rings, and the fundamental questions were, why is Saturn the only planet with rings, how big are the particles, and what are they made of? Since then, we have received an avalanche of observations of planetary ring systems, both from spacecraft and from Earth. Meanwhile, we have seen steady progress in our understanding of the myriad ways in which gravity, fluid and statistical mechanics, and electromagnetism can combine to shape the distribution of the submicron-to-several-meter size particles which comprise ring systems into the complex webs of structure that we now know them to display. Insights gained from studies of these giant dynamical analogs have carried over into improved understanding of the formation of the planets themselves from particle disks, a subject very close to Jim's heart. The now-complete reconnaissance of the gas giant planets by spacecraft has revealed that ring systems are invariably found in association with families of regular satellites, and there is ark emerging perspective that they are not only physically but causally linked. There is also mounting evidence that many features or aspects of all planetary ring systems, if not the ring systems themselves, are considerably younger than the solar system

  8. Photon antibunching and bunching in a ring-resonator waveguide quantum electrodynamics system.

    Chen, Zihao; Zhou, Yao; Shen, Jung-Tsung


    We numerically investigate the photonic state generation and its nonclassical correlations in a ring-resonator waveguide quantum electrodynamics system. Specifically, we discuss photon antibunching and bunching in various scenarios, including the imperfect resonator with backscattering and dissipations. Our numerical results indicate that an imperfect ring resonator with backscattering can enhance the quality of antibunching. In addition, we also identify the quantum photonic halo phenomenon in the photon scattering dynamics and the shoulder effect in the second-order correlation function.

  9. Angular Distribution of Products in Deep Inelastic Collision of 19F+27Al%19F+27Al深部非弹性碰撞产物的角分布

    董玉川; 李志常; 路秀琴; 赵葵; 周平; 刘建成; Sergey Yu-Kun; 王琦; 李松林; 段利敏; 吴和宇; 徐华根; 陈若富; 徐瑚珊; 韩建龙


    完成了19F+27Al深部非弹性碰撞产物的角分布测量. 初步分析了反应产物B, C, N, O, F, Ne, Na, Mg和Al的实验室系角分布, 展现出深部非弹性反应机制的特点, 显示了反应系统随时间的演化过程.

  10. The demise of Phobos and development of a Martian ring system

    Black, Benjamin A.; Mittal, Tushar


    All of the gas giants in our Solar System host ring systems, in contrast to the inner planets. One proposed mechanism of planetary ring formation is disruption or mass shedding of moons. The orbit of Phobos, the larger of Mars's two moonlets, is gradually spiralling inwards towards Mars and the moon is experiencing increasing tidal stresses. Eventually, Phobos will either break apart to form a ring or it will crash into Mars. We evaluate these outcomes based on geologic, spectral and theoretical constraints, in conjunction with a geotechnical model that helps us determine the strength of Phobos. Our analysis suggests that much of Phobos is composed of weak, heavily damaged materials. We suggest that--with continued inward migration of the moon--the weakest material will disperse tidally in 20 to 40 million years to form a Martian ring. We predict that this ring will persist for 106 to 108 years and will initially have a comparable mass density to that of Saturn's rings. Any large fragment of Phobos that is strong enough to escape tidal breakup will eventually collide with Mars in an oblique, low-velocity impact. Our analysis of the evolution of Phobos underscores the potential orbital and topographic consequences of the growth and self-destruction of other inwardly migrating moons, including those that met their demise early in our Solar System's history.

  11. Assessment of different formation scenarios for the ring system of (10199) Chariklo

    Melita, M. D.; Duffard, R.; Ortiz, J. L.; Campo-Bagatin, A.


    Context. The discovery that the Centaur (10199) Chariklo possesses a ring system opens questions about their origin. Aims: We here asses the plausibility of different scenarios for the origin of the observed ring system. Methods: We first consider the possibility that the material of the ring originated in the disruption of a satellite that had reached a critical distance from the Centaur. We discuss the conditions for the putative satellite to approach the Centaur as a consequence of tidal interaction. A three-body encounter is also considered as a transport mechanism. In addition, we study the case in which the ring is formed by the ejecta of a cratering collision on the Centaur and we constrain the collision parameters and the size of the resulting crater of the event. Finally, we consider that the ring material originates from a catastrophic collision between a background object and a satellite located at a distance corresponding to the the current location of the ring. We compute the typical timescales for these scenarios. Results: We estimate that in order to be tidally disrupted a satellite would have had to be larger than approximately 6.5 km at the location of the rings. However the tidal interaction is rather weak for objects of the size of outer solar system bodies at the ring location, therefore we considered other more effective mechanisms by which a satellite might have approached the Centaur. Collisonal scenarios are both physically plausible for the formation, but semianalytical estimations indicate that the probability of the corresponding collisions is low under current conditions.

  12. CAD/CAE system for the ring planetary reducer with small tooth number difference

    谢永春; QI; Shifeng; 等


    A CAD/CAE system of the ring-type planetary reducer with small tooth number difference is presented.It is a parameterized CAD/CAE system adopting the object-oriented technique and comprising in itself the geometric feature database(including the modules of ring-plates with ineer te4eth,eccentric shaft modules and output shaft modules),standard componentdatabase and material database.In cdomparison with design by handwork,this computer aided design and analysis system has the advantages of improved quality,shortened design period and reduced cost.The reliability of the system has been verified by a illustrative example.

  13. Synthetic studies on maitotoxin. 1. Stereoselective synthesis of the C'D'E'F'-ring system having a side chain.

    Morita, Masayuki; Ishiyama, Seishi; Koshino, Hiroyuki; Nakata, Tadashi


    The stereoselective synthesis of the maitotoxin C'D'E'F'-ring system having a side chain has been accomplished through a convergent strategy. The key reactions include Horner-Wadsworth-Emmons coupling of the C'D'E'-ring and the side chain and subsequent construction of the F'-ring by silane reduction of dihydropyran.

  14. Theoretical Analysis of Neutron Double-Differential Cross Section of n + 19F at 14.2 MeV

    DUAN Jun-Feng; YAN Yu-Liang; SUN Xiao-Jun; ZHANG Yue; ZHANG Jing-Shang


    A new light nuclear reaction model has been developed and the double-differential measurements of 1p shell nuclei have been analyzed successfully. Now, the application of this model is expanded to 19F of the 2s-1d shell nucleus. The double-differential cross section of total outgoing neutron for n + 19F reactions at En = 14.2 MeV has been calculated and analyzed, which agrees fairly well with the experimental measurements. In this paper, the contributions from different reaction channels to the double-differential cross sections have been analyzed in detail. The calculations indicate that this light nuclear reaction model is also able to be used for the 2s-1d shell nucleus so long as the related level scheme could be provided sufficiently.

  15. The stability of the oscillation motion of charged grains in the Saturnian ring system

    Xu, R.-L.; Houpis, H. L. F.


    A perturbation approach for the gravitoelectrodynamic forces encountered in the corotating plasma environment of Saturn is used to determine the stability of charged grains, given a random initial velocity. Attention is given to the implications of the Northrop and Hill (1982) and Mendis et al. (1982) results for the formation of the Saturnian ring system, and it is suggested that the marginal z stability radius at 1.5245 Saturn radii for Kepler-launched particles is due to an erosion process with ejecta of the order 0.05-0.5 microns, rather than that of the previously suggested plasma. The diffuseness of the Saturnian rings beyond the F ring is also explained in terms of instability, while a new critical radius for r instability is suggestd for the optical depth feature at 1.72 Saturn radii. The F ring is analyzed in detail.

  16. Preliminary study of the 19F(7Li,7Be)19O reaction at 52 MeV with MAGNEX

    Cavallaro, M; Cappuzzello, F; Carbone, D; Foti, A; Orrigo, S E A; Rodrigues, M R D; Schillaci, M; Borello-Lewin, T; Petrascu, H


    The 19F(7Li,7Be)19O charge-exchange reaction at 52 MeV incident energy has been performed at INFN-LNS in Catania using the MAGNEX spectrometer. The use of an algebraic ray-reconstruction technique has allowed to extract the 19O excitation energy spectrum and the experimental angular distributions obtained with a single angular setting of the spectrometer.

  17. Capture, acceleration and bunching rf systems for the MEIC booster and storage rings

    Wang, Shaoheng [Jefferson Lab, Newport News, VA; Guo, Jiquan [Jefferson Lab, Newport News, VA; Lin, Fanglei [Jefferson Lab, Newport News, VA; Morozov, Vasiliy [Jefferson Lab, Newport News, VA; Rimmer, Robert A. [Jefferson Lab, Newport News, VA; Wang, Haipeng [Jefferson Lab, Newport News, VA; Zhang, Yuhong [Jefferson Lab, Newport News, VA


    The Medium-energy Electron Ion Collider (MEIC), proposed by Jefferson Lab, consists of a series of accelerators. The electron collider ring accepts electrons from CEBAF at energies from 3 to 12 GeV. Protons and ions are delivered to a booster and captured in a long bunch before being ramped and transferred to the ion collider ring. The ion collider ring accelerates a small number of long ion bunches to colliding energy before they are re-bunched into a high frequency train of very short bunches for colliding. Two sets of low frequency RF systems are needed for the long ion bunch energy ramping in the booster and ion collider ring. Another two sets of high frequency RF cavities are needed for re-bunching in the ion collider ring and compensating synchrotron radiation energy loss in the electron collider ring. The requirements from energy ramping, ion beam bunching, electron beam energy compensation, collective effects, beam loading and feedback capability, RF power capability, etc. are presented. The preliminary designs of these RF systems are presented. Concepts for the baseline cavity and RF station configurations are described, as well as some options that may allow more flexible injection and acceleration schemes.

  18. Multimodal Perfluorocarbon Nanoemulsions for 19F MRI, Ultrasonography, and Catalysis of MRgFUS-Mediated Drug Delivery

    Rapoport, N.; Nam, K.-H.; Christensen, D. A.; Kennedy, A. M.; Parker, D. L.; Payne, A. H.; Todd, N.; Shea, J. E.; Scaife, C. L.


    Perfluorocarbon nanoemulsions can target lipophilic therapeutic agents to solid tumors and simultaneously provide for monitoring nanocarrier biodistribution via ultrasonography and/or 19F MRI. In the first generation of block copolymer stabilized perfluorocarbon nanoemulsions, perfluoropentane (PFP) was used as the droplet forming compound. Although manifesting excellent therapeutic and ultrasound imaging properties, PFP nanoemulsions were unstable at storage, difficult to handle, and underwent droplet-to-bubble transition upon injection that was hard to control. To solve the above problems, perfluoro-15-crown-5-ether (PFCE) was used as a core forming compound in the second generation of block copolymer stabilized perfluorocarbon nanoemulsions. In the present paper, acoustic, imaging, and therapeutic properties of unloaded and paclitaxel (PTX) loaded PFCE nanoemulsions are reported. The size of paclitaxel-loaded PFCE nanodroplets (300 nm to 500 nm depending on emulsification conditions) favors their passive accumulation in tumor tissue. PFCE nanodroplets manifest both ultrasound and 19F MR contrast properties, which allows the use of multimodal imaging to monitor nanodroplet biodistribution. Ultrasonography and 19F MRI produced consistent results on nanodroplet biodistribution. Sonication with 1-MHz therapeutic ultrasound triggered reversible droplet-to-bubble transition in PFCE nanoemulsions. Microbubbles formed by acoustic vaporization underwent stable cavitation. In a pilot study on ultrasound-mediated therapy of a large breast cancer tumor, paclitaxel-loaded PFCE nanoemulsions combined with 1-MHz ultrasound (MI≥1.75) showed excellent therapeutic properties. Anticipated mechanisms of the observed effects are discussed.

  19. A Study of Storage Ring Requirements for an Explosive Detection System Using NRA Method

    Wang, Tai-Sen


    The technical feasibility of an explosives detection system based on the nuclear resonance absorption (NRA) of gamma rays in nitrogen-rich materials was demonstrated at Los Alamos National Laboratory (LANL) in 1993 by using an RFQ proton accelerator and a tomographic imaging prototype.* The study is being continued recently to examine deployment of such an active interrogation system in realistic scenarios. The approach is to use a cyclotron and electron-cooling-equipped storage rings(s) to provide the high quality and high current proton beam needed in a practical application. In this work, we investigate the storage ring requirements for a variant of the airport luggage inspection system considered in the earlier LANL experiments. Estimations are carried out based on the required inspection throughput, the gamma ray yield, the proton beam emittance growth due to scattering with the photon-production target, beam current limit in the storage ring, and the electron cooling rate. Studies using scaling and reas...

  20. Auto-production of biosurfactants reverses the coffee ring effect in a bacterial system

    Sempels, Wouter; de Dier, Raf; Mizuno, Hideaki; Hofkens, Johan; Vermant, Jan


    The deposition of material at the edge of evaporating droplets, known as the ‘coffee ring effect’, is caused by a radially outward capillary flow. This phenomenon is common to a wide array of systems including colloidal and bacterial systems. The role of surfactants in counteracting these coffee ring depositions is related to the occurrence of local vortices known as Marangoni eddies. Here we show that these swirling flows are universal, and not only lead to a uniform deposition of colloids but also occur in living bacterial systems. Experiments on Pseudomonas aeruginosa suggest that the auto-production of biosurfactants has an essential role in creating a homogeneous deposition of the bacteria upon drying. Moreover, at biologically relevant conditions, intricate time-dependent flows are observed in addition to the vortex regime, which are also effective in reversing the coffee ring effect at even lower surfactant concentrations.

  1. The predictable degree property and row reducedness for systems over a finite ring

    Antoulas, A.T.; Kuijper, Margreta; Helmke, U.; Pinto, Raquel; Rosenthal, J.; Polderman, Jan W.; Vinnikov, V.; Zerz, E.


    Motivated by applications in communications, we consider linear discrete time systems over the finite ring $Z_{p^r}$. We solve the open problem of deriving a theory of row reduced representations for these systems. We introduce a less restrictive form of representation than the adapted form

  2. Present status of development of damping ring extraction kicker system for CLIC

    Holma, Janne; Belver-Aguilar, Caroline; Faus-Golfe, Angeles; Toral, Fernando


    The CLIC damping rings will produce ultra-low emittance beam, with high bunch charge, necessary for the luminosity performance of the collider. To limit the beam emittance blow-up due to oscillations, the pulse power modulators for the damping ring kickers must provide extremely flat, high-voltage pulses: specifications call for a 160 ns duration and a flattop of 12.5 kV, 250 A, with a combined ripple and droop of not more than ±0.02 %. The stripline design is also extremely challenging: the field for the damping ring kicker system must be homogenous to within ±0.01 % over a 1 mm radius, and low beam coupling impedance is required. The solid-state modulator, the inductive adder, is a very promising approach to meeting the demanding specifications for the field pulse ripple and droop. This paper describes the initial design of the inductive adder and the striplines of the kicker system.

  3. Present status of development of damping ring extraction kicker system for CLIC

    Holma, Janne; Belver-Aguilar, Caroline; Faus-Golfe, Angeles; Toral, Fernando


    The CLIC damping rings will produce ultra-low emittance beam, with high bunch charge, necessary for the luminosity performance of the collider. To limit the beam emittance blow-up due to oscillations, the pulse power modulators for the damping ring kickers must provide extremely flat, high-voltage pulses: specifications call for a 160 ns duration and a flattop of 12.5 kV, 250 A, with a combined ripple and droop of not more than \\pm0.02 %. The stripline design is also extremely challenging: the field for the damping ring kicker system must be homogenous to within \\pm0.01 % over a 1 mm radius, and low beam coupling impedance is required. The solid-state modulator, the inductive adder, is a very promising approach to meeting the demanding specifications for the field pulse ripple and droop. This paper describes the initial design of the inductive adder and the striplines of the kicker system.

  4. Configuration maintaining control of three-body ring tethered system based on thrust compensation

    Huang, Panfeng; Liu, Binbin; Zhang, Fan


    Space multi-tethered systems have shown broad prospects in remote observation missions. This paper mainly focuses on the dynamics and configuration maintaining control of space spinning three-body ring tethered system for such mission. Firstly, we establish the spinning dynamic model of the three-body ring tethered system considering the elasticity of the tether using Newton-Euler method, and then validate the suitability of this model by numerical simulation. Subsequently, LP (Likins-Pringle) initial equilibrium conditions for the tethered system are derived based on rigid body's equilibrium theory. Simulation results show that tether slack, snapping and interaction between the tethers exist in the three-body ring system, and its' configuration can not be maintained without control. Finally, a control strategy based on thrust compensation, namely thrust to simulate tether compression under LP initial equilibrium conditions is designed to solve the configuration maintaining control problem. Control effects are verified by numerical simulation compared with uncontrolled situation. Simulation results show that the configuration of the three-body ring tethered system could maintain under this active control strategy.

  5. Synchronization of N different coupled chaotic systems with ring and chain connections

    LIU Yan; L(U) Ling


    Synchronization of N different coupled chaotic systems with ring and chain Lorenz system, and the R(o)ssler system are used as examples in verifying effectiveness of the method. Based on the Lyapunov stability theory, the form of the controller is designed and the area of the coupling coefficients is determined. Simulations indicate that global synchronization of the N different chaotic systems can be realized by choosing appropriate coupling coefficients by using the controller.

  6. Block Fusion Systems and the Center of the Group Ring

    Jacobsen, Martin Wedel

    This thesis develops some aspects of the theory of block fusion systems. Chapter 1 contains a brief introduction to the group algebra and some simple results about algebras over a field of positive characteristic. In chapter 2 we define the concept of a fusion system and the fundamental property...

  7. Comments on the interaction between the F ring system and its new discovered objects

    Giuliatti Winter, S. M.; Ferreira Gonsalves, M. A.; Winter, O.; Cardozo Mourao, D.


    The arrival of the Cassini spacecraft to the saturnian system brought a huge amount of data. Among them there is the discovery of three satellites close to the F ring (S/2004 S3, S/2004 S4 and S/2004 S6) and two tenuous rings, one close to the satellite Prometheus (R 2004/S2) and other coorbital to the satellite Atlas (R 2004/ S1). Before the inclusion of these new bodies, this region already had some unexplained features. The F ring presents strands, kinks and clumps probably related to the close satellites Prometheus and Pandora and embedded moonlets. In this work we analysed the behaviour of the ring particles strands disturbed by a sample of small objects varying in size and orbital elements. The new discovered objects is part of this sample of objects. As an example, we showed that an object of 10km in radius forms a gap in the outer strand. There are no scattered particles, the gap is formed by particles which collide with the object. We also analysed a sample of hypothetical objects lying in the F ring region taking into account the perturbation of Prometheus, Pandora and the oblateness of Saturn. This analysis is primarily performed using the secular perturbation theory. Then we computed the Lyapunov characteristic exponent for these objects. These results are presented for a range of semi major axes and eccentricities. By using numerical simulation we can verify that the perturbation of Prometheus on the new rings causes a variation only in R 2004/S2. This perturbation is enough to open a gap and scatter particles in the direction of the F ring region. Acknowledgements: SMGW thanks FUNDUNESP, OCW thanks FUNDUNESP and CNPq, MAFG and DCM thank CAPES for the financial support.

  8. Site-specific solvent exposure analysis of a membrane protein using unnatural amino acids and {sup 19}F nuclear magnetic resonance

    Shi, Pan; Li, Dong [Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230026 (China); Chen, Hongwei [High Magnetic Field Laboratory, Chinese Academy of Science, Hefei, Anhui 230031 (China); Xiong, Ying [Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230026 (China); Tian, Changlin, E-mail: [Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230026 (China); High Magnetic Field Laboratory, Chinese Academy of Science, Hefei, Anhui 230031 (China)


    Highlights: {yields} Solvent isotope shift analysis of {sup 19}F-tfmF in different H{sub 2}O/D{sub 2}O molar ratio. {yields} Correlation between solvent isotope shift of {sup 19}F-spins and solvent exposure analysis. {yields} Solvent exposure analysis of membrane proteins. -- Abstract: Membrane proteins play an essential role in cellular metabolism, transportation and signal transduction across cell membranes. The scarcity of membrane protein structures has thus far prevented a full understanding of their molecular mechanisms. Preliminary topology studies and residue solvent exposure analysis have the potential to provide valuable information on membrane proteins of unknown structure. Here, a {sup 19}F-containing unnatural amino acid (trimethylfluoro-phenylalanine, tfmF) was applied to accomplish site-specific {sup 19}F spin incorporation at different sites in diacylglycerol kinase (DAGK, an Escherichia coli membrane protein) for site-specific solvent exposure analysis. Due to isotope effect on {sup 19}F spins, a standard curve for {sup 19}F-tfmF chemical shifts was drawn for varying solvent H{sub 2}O/D{sub 2}O ratios. Further site-specific {sup 19}F solvent isotope shift analysis was conducted for DAGK to distinguish residues in water-soluble loops, interfacial areas or hydrophobic membrane regions. This site-specific solvent exposure analysis method could be applied for further topological analysis of other membrane proteins.

  9. A comparison of chemical shift sensitivity of trifluoromethyl tags: optimizing resolution in {sup 19}F NMR studies of proteins

    Ye, Libin; Larda, Sacha Thierry; Frank Li, Yi Feng [University of Toronto, UTM, Department of Chemistry (Canada); Manglik, Aashish [Stanford University School of Medicine, Department of Molecular and Cellular Physiology (United States); Prosser, R. Scott, E-mail: [University of Toronto, UTM, Department of Chemistry (Canada)


    The elucidation of distinct protein conformers or states by fluorine ({sup 19}F) NMR requires fluorinated moieties whose chemical shifts are most sensitive to subtle changes in the local dielectric and magnetic shielding environment. In this study we evaluate the effective chemical shift dispersion of a number of thiol-reactive trifluoromethyl probes [i.e. 2-bromo-N-(4-(trifluoromethyl)phenyl)acetamide (BTFMA), N-(4-bromo-3-(trifluoromethyl)phenyl)acetamide (3-BTFMA), 3-bromo-1,1,1-trifluoropropan-2-ol (BTFP), 1-bromo-3,3,4,4,4-pentafluorobutan-2-one (BPFB), 3-bromo-1,1,1-trifluoropropan-2-one (BTFA), and 2,2,2-trifluoroethyl-1-thiol (TFET)] under conditions of varying polarity. In considering the sensitivity of the {sup 19}F NMR chemical shift to the local environment, a series of methanol/water mixtures were prepared, ranging from relatively non-polar (MeOH:H{sub 2}O = 4) to polar (MeOH:H{sub 2}O = 0.25). {sup 19}F NMR spectra of the tripeptide, glutathione ((2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl] -2-sulfanylethyl]carbamoyl}butanoic acid), conjugated to each of the above trifluoromethyl probes, revealed that the BTFMA tag exhibited a significantly greater range of chemical shift as a function of solvent polarity than did either BTFA or TFET. DFT calculations using the B3LYP hybrid functional and the 6-31G(d,p) basis set, confirmed the observed trend in chemical shift dispersion with solvent polarity.

  10. DFT-GIAO calculation of properties of {sup 19}F NMR and stability study of environmentally relevant perfluoroalkylsulfonamides (PFASAmide)

    Mejia-Urueta, Rafael; Mestre-Quintero, Kleyber; Vivas-Reyes, Ricardo, E-mail: [Grupo de Quimica Cuantica y Teorica, Facultad de Ciencias Exactas y Naturales, Universidad de Cartagena, Cartagena (Colombia)


    Perfluorinated organic compounds (POCs), such as perfluorooctanesulfonate (PFOS) and perfluoroalkylsulfonamide (PFASA) are compounds that have recently attracted considerable attention worldwide because of its high persistence and wide distribution in the environment. Among the spectroscopic methods used to study the PFASA, {sup 19}F nuclear magnetic resonance (NMR {sup 19}F) is very effective, due to its ability to determine concentrations of PFASA in biological samples and measure pollution in water samples. For this reason, a theoretical study of the properties of {sup 19}F NMR was performed. In this study we have determined the shielding constant ({sigma}) for different fluorine nucleus of the 18 molecules under study, using density functional theory (DFT) and GIAO method with the B3PW91/6-31+G(d,p) level of calculation. The {sigma} calculations were made at vacuum and in presence of a solvent. The values of chemical shifts ({delta}), were also calculated in a different level of theory. The best results were obtained with the level of calculation DFT-GIAO/B3PW91/6-31+G(d,p) by considering the solvent such as dimethylsulfoxide (DMSO), chloroform (CHCl{sub 3}), acetone (CH{sub 3}COCH{sub 3}) and methanol (CH{sup 3}OH). The results were interpreted in terms of calculated hardness at DFT/B3PW91/6-31+G(d, p) level. The behaviour of the hardness was higher in the molecules of four carbons PFASA than eight carbons. This explain theoretically resistance of four carbons PFAS to be transformed into perfluorobutanesulfonate (PFBS). (author)

  11. Dot Blot para determinar la identidad antigénica en vacunas conjugadas contra Streptococcus pneumoniae serotipo 19F

    Osmir Cabrera-Blanco


    Full Text Available Las autoridades regulatorias recomiendan el uso de técnicas de Resonancia Magnética Nuclear o técnicas serológicas para la determinación de la identidad de los antígenos presentes en las vacunas conjugadas. Con la aparición de las vacunas conjugadas multivalentes, se ha hecho necesario recurrir a técnicas inmunoquímicas con la utilización de anticuerpos monoclonales para aumentar la sensibilidad en la determinación de la identidad de los antígenos en dichas vacunas conjugadas. El objetivo del presente trabajo fue establecer las condiciones óptimas de trabajo que permitieran utilizar la técnica del Dot Blot para determinar la identidad de los antígenos en vacunas conjugadas de Streptococcus pneumoniae serotipo 19F. Para ello se estudiaron los tiempos de incubación, la influencia del reactivo en la solución de bloqueo; también las concentraciones óptimas del anticuerpo monoclonal y de los ingredientes farmacéuticos activos, así como los volúmenes de aplicación óptimos para estos y vacunas. Se utilizó un anticuerpo monoclonal contra el polisacárido capsular del serotipo 19F de neumococo. Las muestras empleadas en este trabajo fueron lotes de ingredientes farmacéuticos activos de conjugados de polisacárido capsular 19F y lotes de un candidato vacunal cubano conjugado heptavalente contra neumococos. Los resultados mostraron que para la determinación de la identidad antigénica fueron suficientes 10 µL de muestras de los principios activos a una concentración de 125 µg/mL e igual volumen para las vacunas heptavalentes. Quedó demostrado que una concentración de 1 µg/mL para el anticuerpo monoclonal y tiempos de incubación de 30 min a 37 °C fueron suficientes para la determinación. Estos resultados permiten concluir que quedaron establecidas las condiciones óptimas de trabajo para determinar la identidad antigénica por Dot Blot del polisacárido capsular de S. pneumoniae serotipo 19F presente en las vacunas

  12. Langevin study of neutron emission in the reactions 16O+181Ta and 19F+178Hf

    YE Wei; WU Feng; YANG Hong-Wei


    The pre-scission neutrons measured in the reactions 16O+181Ta and 19F+178Hf are studied via a Langevin equation coupled with a statistical decay model.We find that because of the mass asymmetry of different entrance channels,the spin distributions of compound nuclei would be different,consequently,the measured neutrons in these two reactions would also different.This means that the entrance channel will affect the particle emission in the fission process of hot nuclei.

  13. High-resolution and high-temperature {sup 19} F MAS NMR study of fluorozirconate glasses and liquids

    Youngman, R.E.; Sem, S. [Corning Inc., NY (United States)


    This paper reports the first results of a high-resolution and high-temperature {sup 19}F MAS NMR spectroscopic study of the atomic structure and its temperature dependence in two binary Zr F{sub 4} (Z B) glasses with 62 and 70 mol % Zr F{sub 4} and a multicomponent ZBLAN (51.7% Zr-F{sub 4}-20.7% Ba F{sub 2}-4.5% La F{sub 3}-3.4% Al F{sub 3}-19.7% Na F) glass.

  14. Detection and differentiation of neutral organic compounds by 19F NMR with a tungsten calix[4]arene imido complex.

    Zhao, Yanchuan; Swager, Timothy M


    Fluorinated tungsten calix[4]arene imido complexes were synthesized and used as receptors to detect and differentiate neutral organic compounds. It was found that the binding of specific neutral organic molecules to the tungsten centers induces an upfield shift of the fluorine atom appended on the arylimido group, the extent of which is highly dependent on electronic and steric properties. We demonstrate that the specific bonding and size-selectivity of calix[4]arene tungsten-imido complex combined with (19)F NMR spectroscopy is a powerful new method for the analysis of complex mixtures.

  15. Transverse beam feedback system for PLS storage ring

    Huang, J Y; Kim, D T; Kang, H S; Hwang, W H; Nam, S H


    As the stored beam current increases over 240 mA, transverse coupled-beam instability limits higher beam current in Pohang Light Source. A bunch by bunch transverse feedback system has been developed to cure these beam instabilities. It consists of beam oscillation detectors, betatron phase adjuster, power amplifiers and a stripline kicker. Design of each circuit and its functions are described with simple trigonometric equations. The result of the beam test has shown more than 30 dB damping of the beam oscillation in the full bandwidth of the system.

  16. Fungal Origins of the Bicyclo[2.2.2]diazaoctane Ring System of Prenylated Indole Alkaloids

    Finefield, Jennifer M.; Frisvad, Jens C.; Sherman, David H.


    Over eight different families of natural products consisting of nearly 70 secondary metabolites that contain the bicyclo[2.2.2]diazaoctane ring system have been isolated from various Aspergillus, Penicillium, and Malbranchea species. Since 1968, these secondary metabolites have been the focus of ...

  17. On the Relation between Stable Matrix Fraction Factorizations and Regulable Realizations of Linear Systems Over Rings,


    they apply to algebraic terms, the reader should consult Bourbaki Ill. all possible interpretations. Examples of rings of system-theoretic interest are... Bourbaki [1, sect. 11.2.71). A fstrictly) proper map from Xl: -" UfzJ with S ’A[z] into S- B[z) will be. by definition, one which is a (strictly

  18. Entering the boxing ring: intergroup behavior in multiteam systems

    Wijnmaalen, Julia Roswitha


    Organizations nowadays need to adjust quickly to new challenges. Consequently they are in need of a form of cooperation to help them react more efficiently. A Multiteam system (MTS) is such a form of cooperation. MTSs are two or more teams that interface directly and interdependently and that need

  19. Entering the boxing ring: intergroup behavior in multiteam systems

    Wijnmaalen, Julia


    Organizations nowadays need to adjust quickly to new challenges. Consequently they are in need of a form of cooperation to help them react more efficiently. A Multiteam system (MTS) is such a form of cooperation. MTSs are two or more teams that interface directly and interdependently and that need

  20. Synchronization of Coupled Chaotic Systems with Ring Connection Based on Special Antisymmetric Structure

    Xiangyong Chen


    Full Text Available This paper considers the complete synchronization problem for coupled chaotic systems with ring connections. First, we use a direct design method to design a synchronization controller. It transforms the error system into a stable system with special antisymmetric structure. And then, we get some simple stability criteria of achieving the complete synchronization. These criteria are not only easily verified but also improve and generalize previous known results. Finally, numerical examples are provided to demonstrate the effectiveness of the theoretical analysis.

  1. Tunable optical analog to electromagnetically induced transparency in graphene-ring resonators system

    Wang, Yonghua; Xue, Chenyang; Zhang, Zengxing; Zheng, Hua; Zhang, Wendong; Yan, Shubin


    The analogue of electromagnetically induced transparency in optical ways has shown great potential in optical delay and quantum-information technology due to its flexible design and easy implementation. The chief drawback for these devices is the bad tunability. Here we demonstrate a tunable optical transparency system formed by graphene-silicon microrings which could control the transparent window by electro-optical means. The device consists of cascaded coupled ring resonators and a graphene/graphene capacitor which integrated on one of the rings. By tuning the Fermi level of the graphene sheets, we can modulate the round-trip ring loss so that the transparency window can be dynamically tuned. The results provide a new method for the manipulation and transmission of light in highly integrated optical circuits and quantum information storage devices.

  2. Self-assembly in chains, rings, and branches: a single component system with two critical points.

    Rovigatti, Lorenzo; Tavares, José Maria; Sciortino, Francesco


    We study the interplay between phase separation and self-assembly in chains, rings, and branched structures in a model of particles with dissimilar patches. We extend Wertheim's first order perturbation theory to include the effects of ring formation and to theoretically investigate the thermodynamics of the model. We find a peculiar shape for the vapor-liquid coexistence, featuring reentrant behavior in both phases and two critical points, despite the single-component nature of the system. The emergence of the lower critical point is caused by the self-assembly of rings taking place in the vapor, generating a phase with lower energy and lower entropy than the liquid. Monte Carlo simulations of the same model fully support these unconventional theoretical predictions.

  3. Tissue culture system using a PANDA ring resonator and wavelength router for hydroponic plant.

    Kamoldilok, Surachart; Suwanpayak, Nathaporn; Suttirak, Saisudawan; Yupapin, Preecha P


    A novel system of nanofluidics trapping and delivery, which is known as a tissue culture system is proposed. By using the intense optical pulse(i.e., a soliton pulse) and a system constructed by a liquid core waveguide, the optical vortices (gradient optical fields/wells) can be generated, where the trapping tools in the same way as the optical tweezers in the PANDA ring resonator can be formed. By controlling the suitable parameters, the intense optical vortices can be generated within the PANDA ring resonator, in which the nanofluidics can be trapped and moved (transported) dynamically within the Tissue culture system(a wavelength router), which can be used for tissue culture and delivery in the hydroponic plant system.

  4. An innovative seismic bracing system based on a superelastic shape memory alloy ring

    Gao, Nan; Jeon, Jong-Su; Hodgson, Darel E.; DesRoches, Reginald


    Shape memory alloys (SMAs) have great potential in seismic applications because of their remarkable superelasticity. Seismic bracing systems based on SMAs can mitigate the damage caused by earthquakes. The current study investigates a bracing system based on an SMA ring which is capable of both re-centering and energy dissipation. This lateral force resisting system is a cross-braced system consisting of an SMA ring and four tension-only cable assemblies, which can be applied to both new construction and seismic retrofit. The performance of this bracing system is examined through a quasi-static cyclic loading test and finite element (FE) analysis. This paper describes the experimental design in detail, discusses the experimental results, compares the performance with other bracing systems based on SMAs, and presents an Abaqus FE model calibrated on the basis of experimental results to simulate the superelastic behavior of the SMA ring. The experimental results indicate that the seismic performance of this system is promising in terms of damping and re-centering. The FE model can be used in the simulation of building structures using the proposed bracing system.


    Shaik Naseera


    Full Text Available In distributed systems, nodes are connected at different geographical locations. As a part of effective resource utilization, the data and resources are shared among these nodes. A leader or pioneer is necessary to take care of this resource sharing process by eliminating conflicting among the nodes. The shared resources are to be accessed in a fair and optimal manner among all the nodes in the network. This makes the importance of electing a leader which can coordinate with all the nodes and make fair use of resources among the nodes. As nodes are distributed in different geographical locations and factors influencing its operation make it inevitable that a leader may go down temporarily or permanently. In such case a new leader has to be elected for coordination. The time taken to elect a new leader is one of the crucial factors in improving the performance of the system. In this paper, we propose a new approach for leader election to optimize the time taken for the nodes to elect the leader.

  6. Analyses for Mechanical Stability for Systems of Ions and Atoms Associated with Rings, Cages, and Crypts.


    34 11). P. M. Morse and II. Feshback, Methods of Theoretical Physics (McGraw-Hill, New York, 19S3) I2. G. Arfken , Mathematical Methods for Physicists...useful for the elaboration of the nature of forces which operate in solvated ionic systems. 4,7-10 These methods , we believe, also can be useful for...examined rings, polyigons, and polyhedra all of which share similar mathematical properties. -23- The examination of the system of a continuous

  7. Adaptive coupled synchronization of non-autonomous systems in ring networks

    Guo Liu-Xiao; Xu Zhen-Yuan; Hu Man-Feng


    The adaptive coupled synchronization method for non-autonomous systems is proposed. This method can avoid estimating the value of coupling coefficient.Under the uniform Lipschitz assumption, we derive the asymptotical synchronization for a general coupling ring network with N identical non-autonomons systems, even when N is large enough. Strict theoretical proofs are given. Numerical simulations illustrate the effectiveness of the present method.

  8. Superfluorinated PEI Derivative Coupled with (99m) Tc for ASGPR Targeted (19) F MRI/SPECT/PA Tri-Modality Imaging.

    Guo, Zhide; Gao, Mengna; Song, Manli; Li, Yesen; Zhang, Deliang; Xu, Duo; You, Linyi; Wang, Liangliang; Zhuang, Rongqiang; Su, Xinhui; Liu, Ting; Du, Jin; Zhang, Xianzhong


    Fluorinated polyethylenimine derivative labeled with radionuclide (99m) Tc is developed as a (19) F MRI/SPECT/PA multifunctional imaging agent with good asialoglycoprotein receptors (ASGPR)-targeting ability. This multifunctional agent is safe and suitable for (19) F MRI/SPECT/PA imaging and has the potential to detect hepatic diseases and to assess liver function, which provide powerful support for the development of personalized and precision medicine.

  9. Determinantal rings

    Bruns, Winfried


    Determinantal rings and varieties have been a central topic of commutative algebra and algebraic geometry. Their study has attracted many prominent researchers and has motivated the creation of theories which may now be considered part of general commutative ring theory. The book gives a first coherent treatment of the structure of determinantal rings. The main approach is via the theory of algebras with straightening law. This approach suggest (and is simplified by) the simultaneous treatment of the Schubert subvarieties of Grassmannian. Other methods have not been neglected, however. Principal radical systems are discussed in detail, and one section is devoted to each of invariant and representation theory. While the book is primarily a research monograph, it serves also as a reference source and the reader requires only the basics of commutative algebra together with some supplementary material found in the appendix. The text may be useful for seminars following a course in commutative ring theory since a ...

  10. Impact of fiber ring laser configuration on detection capabilities in FBG based sensor systems

    Osuch, Tomasz; Kossek, Tomasz; Markowski, Konrad


    In this paper fiber ring lasers (FRL) as interrogation units for distributed fiber Bragg grating (FBG) based sensor networks are studied. In particular, two configurations of the fiber laser with erbium-doped fiber amplifier (EDFA) and semiconductor optical amplifier (SOA) as gain medium were analyzed. In the case of EDFA-based fiber interrogation systems, CW as well as active-mode locking operation were taken into account. The influence of spectral overlapping of FBGs spectra on detection capabilities of examined FRLs are presented. Experimental results show that the SOA-based fiber laser interrogation unit can operate as a multi-parametric sensing system. In turn, using an actively mode-locked fiber ring laser with an EDFA, an electronically switchable FBG based sensing system can be realized.

  11. Design of the Injection and extraction system and related machine protection for the Clic Damping Rings

    Apsimon, Robert; Barnes, Mike; Borburgh, Jan; Goddard, Brennan; Papaphilippou, Yannis; Uythoven, Jan


    Linear machines such as CLIC have relatively low rates of collision between bunches compared to their circular counterparts. In order to achieve the required luminosity, a very small spot size is envisaged at the interaction point, thus a low emittance beam is needed. Damping rings are essential for producing the low emittances needed for the CLIC main beam. It is crucial that the beams are injected and extracted from the damping rings in a stable and repeatable fashion to minimise emittance blow-up and beam jitter at the interaction point; both of these effects will deteriorate the luminosity at the interaction point. In this paper, the parameters and constraints of the injection and extraction systems are considered and the design of these systems is optimised within this parameter space. Related machine protection is considered in order to prevent damage from potential failure modes of the injection and extraction systems.

  12. 19F+27Al反应产物的角分布、角分散与耗散机制%Angular Distributions and Angular Dispersions of the Dissipative Products in 19F+27Al Reaction

    董玉川; 李志常; 路秀琴; 赵葵; 周平; 刘建成; Sergey Yu Kun; 王琦; 李松林; 段利敏; 吴和宇; 徐华根; 陈若富; 徐瑚珊; 韩建龙


    完成了114MeV 19F+27Al深部非弹性碰撞产物的角分布测量. 分析了反应产物B,C,N,O,F,Ne,Na,Mg和Al的实验室系角分布,讨论了反应形成的中间双核系统随时间演化过程中角分布所表现出的耗散特点. 从实验上提取了反应产物各元素的角分散参数并作了角分散参数的理论拟合,讨论了角分散参数的物理意义以及角分散参数与耗散反应产物的电荷数Z之间的依赖关系.

  13. 19F+27Al耗散反应产物激发函数的长程关联%Long-range Correlation of Excitation Functions in Dissipative Heavy Ion Collision of 19F+27Al

    韩建龙; 王琦; 白真; 董玉川; 李松林; 段利敏; 徐瑚珊; 徐华根; 陈若富; 吴和宇; 李志常; 路秀琴; 赵葵; 周平; 刘建成; 许国基; Sergey Yu Kun


    在中国原子能科学研究院的HI- 13串列静电加速器上完成了19F+27Al耗散反应产物的激发函数测量.束流19F的入射能量从110.25 MeV到118.75 MeV, 步长250 keV, 测量了实验室系+57°, +31°, -15°和-29°出射的类弹产物B, C, N, O, F和Ne的激发函数.观测到激发函数具有耗散反应的特征涨落结构, 分析了激发函数之间的长程角度关联以及强烈的电荷数关联.

  14. Controllable multiple-quantum transitions in a T-shaped small quantum dot-ring system

    Chen, Xiongwen, E-mail: [Department of Physics, Huaihua University, Huaihua 418008 (China); Chen, Baoju; Song, Kehui [Department of Physics, Huaihua University, Huaihua 418008 (China); Zhou, Guanghui [Department of Physics and Key Laboratory for Low-Dimensional Quantum Structures and Manipulation (Ministry of Education), Hunan Normal University, Changsha 410081 (China)


    Based on the tight-binding model and the slave boson mean field approximation, we investigate the electron transport properties in a small quantum dot (QD)-ring system. Namely, a strongly correlated QD not only attaches directly to two normal metallic electrodes, but also forms a magnetic control Aharonov–Bohm quantum ring with a few noninteracting QDs. We show that the parity effect, the Kondo effect, and the multiple Fano effects coexist in our system. Moreover, the parities, defined by the odd- and even-numbered energy levels in this system, can be switched by adjusting magnetic flux phase ϕ located at the center of the quantum ring, which induces multiple controllable Fano-interference energy pathways. Therefore, the constructive and destructive multi-Fano interference transition, the Kondo and Fano resonance transition at the Fermi level, the Fano resonance and ani-resonance transition are realized in the even parity system. They can also be observed in the odd parity system when one adjusts the phase ϕ and the gate voltage V{sub g} applied to the noninteracting QDs. The multi-quantum transitions determine some interesting transport properties such as the current switch and its multi-flatsteps, the differential conductance switch at zero bias voltage and its oscillation or quantization at the low bias voltage. These results may be useful for the observation of multiple quantum effect interplays experimentally and the design of controllable QD-based device.

  15. Controllable multiple-quantum transitions in a T-shaped small quantum dot-ring system

    Chen, Xiongwen; Chen, Baoju; Song, Kehui; Zhou, Guanghui


    Based on the tight-binding model and the slave boson mean field approximation, we investigate the electron transport properties in a small quantum dot (QD)-ring system. Namely, a strongly correlated QD not only attaches directly to two normal metallic electrodes, but also forms a magnetic control Aharonov-Bohm quantum ring with a few noninteracting QDs. We show that the parity effect, the Kondo effect, and the multiple Fano effects coexist in our system. Moreover, the parities, defined by the odd- and even-numbered energy levels in this system, can be switched by adjusting magnetic flux phase ϕ located at the center of the quantum ring, which induces multiple controllable Fano-interference energy pathways. Therefore, the constructive and destructive multi-Fano interference transition, the Kondo and Fano resonance transition at the Fermi level, the Fano resonance and ani-resonance transition are realized in the even parity system. They can also be observed in the odd parity system when one adjusts the phase ϕ and the gate voltage Vg applied to the noninteracting QDs. The multi-quantum transitions determine some interesting transport properties such as the current switch and its multi-flatsteps, the differential conductance switch at zero bias voltage and its oscillation or quantization at the low bias voltage. These results may be useful for the observation of multiple quantum effect interplays experimentally and the design of controllable QD-based device.

  16. A New Family of Topological Rings with Applications in Linear System Theory

    Alpay, Daniel


    Motivated by the Schwartz space of tempered distributions $\\mathscr S^\\prime$ and the Kondratiev space of stochastic distributions $\\mathcal S_{-1}$ we define a wide family of nuclear spaces which are increasing unions of (duals of) Hilbert spaces $\\mathscr H_p^\\prime,p\\in\\mathbb N$, with decreasing norms $\\|\\cdot\\|_p$. The elements of these spaces are functions on a free commutative monoid. We characterize those rings in this family which satisfy an inequality of the form $\\|f \\diamond g\\|_{p} \\leq A(p-q) \\|f\\|_{q}\\|g\\|_{p}$ for all $p\\ge q+d$, where $\\diamond$ denotes the convolution in the monoid, $A(p-q)$ is a strictly positive number and $d$ is a fixed natural number (in this case we obtain commutative topological rings). Such an inequality holds in $\\mathcal S_{-1}$, but not in $\\mathscr S^\\prime$. We give an example of such a ring which contains $\\mathscr S^\\prime$. We characterize invertible elements in these rings and present applications to linear system theory.


    as potential precursors for B-N polymers. we report here new N-phosphyl .... gave the analytically pure compound as a colorless liquid, b.p.: 7'7-78 ”C!0.01 rnm Hg .... Hz). =n.0"1ic'*. Ll. 1,,..= 5.9 1121. 50.30 qc“. S). 38.10 (PC. Ll. I = 3-2.6 1-12).

  18. Are 19F NMR Shifts a Measure for the Nakedness of Fluoride Ions?


    CIF has been attributed to a low, lying electronic transition , which corresponds to electron’ circulation in opposite ses- n the two atoms and results...shielding tensor in the principle axis system in which all off-diagonal elements of the shielding tensor. are zero. Since in the monodentate CHCI3 and...preparations of N(CH3)4F [7] and P(CH3)4, (45] have previously been described. The KF and RbF were dried by fusion in a platinum crucible. The hot clinkers

  19. Vascular rings.

    Backer, Carl L; Mongé, Michael C; Popescu, Andrada R; Eltayeb, Osama M; Rastatter, Jeffrey C; Rigsby, Cynthia K


    The term vascular ring refers to congenital vascular anomalies of the aortic arch system that compress the esophagus and trachea, causing symptoms related to those two structures. The most common vascular rings are double aortic arch and right aortic arch with left ligamentum. Pulmonary artery sling is rare and these patients need to be carefully evaluated for frequently associated tracheal stenosis. Another cause of tracheal compression occurring only in infants is the innominate artery compression syndrome. In the current era, the diagnosis of a vascular ring is best established by CT imaging that can accurately delineate the anatomy of the vascular ring and associated tracheal pathology. For patients with a right aortic arch there recently has been an increased recognition of a structure called a Kommerell diverticulum which may require resection and transfer of the left subclavian artery to the left carotid artery. A very rare vascular ring is the circumflex aorta that is now treated with the aortic uncrossing operation. Patients with vascular rings should all have an echocardiogram because of the incidence of associated congenital heart disease. We also recommend bronchoscopy to assess for additional tracheal pathology and provide an assessment of the degree of tracheomalacia and bronchomalacia. The outcomes of surgical intervention are excellent and most patients have complete resolution of symptoms over a period of time. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Kinetics of membrane binding and dissociation of 5-fluorouracil by pulsed-field-gradient 19F NMR

    Yoshii, Noriyuki; Okamura, Emiko


    The kinetics of membrane binding and dissociation of an anticancer drug, 5-fluorouracil (5FU) is quantified by high resolution NMR with the pulsed-field-gradient technique. The 19F NMR signal of 5FU is analyzed at 293-313 K by the solution of Bloch equation with exchange terms. The rate constants of 5FU binding and dissociation are 0.2 and 4.1 s -1 at 303 K. The 5FU motion in the vertical direction to the membrane surface is restricted as compared with the lateral diffusion, judging from the activation energy (57 kJ/mol) larger than the lateral diffusion in membrane (26 kJ/mol [E. Okamura, N. Yoshii, J. Chem. Phys. 129 (2008) 215102]).

  1. Fission excitation function for 19F + 194,196,198Pt at near and above barrier energies

    Singh Varinderjit


    Full Text Available Fission excitation functions for 19F + 194,196,198Pt reactions populating 213,215,217Fr compound nuclei are reported. Out of these three compound nuclei, 213Fr is a shell closed (N=126 compound nucleus and the other two are away from the shell closure. From a comparison of the experimental fission cross-sections with the statistical model predictions, it is observed that the fission cross-sections are underestimated by the statistical model predictions using shell corrected finite range rotating liquid drop model (FRLDM fission barriers. Further the FRLDM fission barriers are reduced to fit the fission cross-sections over the entire measured energy range.

  2. New Improved Indirect Measurement of the 19F(p, α)16O Reaction at Energies of Astrophysical Relevance

    Indelicato, I.; La Cognata, M.; Spitaleri, C.; Burjan, V.; Cherubini, S.; Gulino, M.; Hayakawa, S.; Hons, Z.; Kroha, V.; Lamia, L.; Mazzocco, M.; Mrazek, J.; Pizzone, R. G.; Romano, S.; Strano, E.; Torresi, D.; Tumino, A.


    Fluorine abundance determination is of great importance in stellar physics to understand s-elements production and mixing processes in asymptotic giant branch (AGB) stars. Up to now, theoretical models overproduce F abundances in AGB stars with respect to the observed values, thus calling for further investigation of the reactions involving fluorine. In particular, the 19F(p, α)16O reaction is the main destruction channel of fluorine at the bottom of the convective envelope in AGB stars, an H-rich environment where it can experience temperatures high enough to determine its destruction, owing to additional mixing processes. In this paper the Trojan horse method (THM) was used to extract the 19F(p, α 0)16O S-factor in the energy range of astrophysical interest (E cm ≈ 0-1 MeV). This is the most relevant channel at the low temperatures (few 107 K) characterizing the bottom of the convective envelope, according to current knowledge. A previous indirect experiment using the THM has observed three resonances in the energy regions below E cm ≈ 450 keV. These energies correspond to typical AGB temperatures, thus implying a significant increase in the reaction rate. Statistics are scarce for performing an accurate separation between resonances, preventing one from drawing a quantitative conclusion about their total widths and spin parities. Before THM measurement, only extrapolations were available below about 500 keV, showing a non-resonant behavior that sharply contradicts the trend of the astrophysical factor at higher energies. A new experiment has been performed to verify the measured TH astrophysical factor and to perform more accurate spectroscopy of the involved resonances.

  3. Feasibility of 19F-NMR for assessing the molecular mobility of flufenamic acid in solid dispersions.

    Aso, Yukio; Yoshioka, Sumie; Miyazaki, Tamaki; Kawanishi, Toru


    The purpose of the present study was to clarify the feasibility of 19F-NMR for assessing the molecular mobility of flufenamic acid (FLF) in solid dispersions. Amorphous solid dispersions of FLF containing poly(vinylpyrrolidone) (PVP) or hydroxypropylmethylcellulose (HPMC) were prepared by melting and rapid cooling. Spin-lattice relaxation times (T1 and T(1rho)) of FLF fluorine atoms in the solid dispersions were determined at various temperatures (-20 to 150 degrees C). Correlation time (tauc), which is a measure of rotational molecular mobility, was calculated from the observed T1 or T1rho value and that of the T1 or T1rho minimum, assuming that the relaxation mechanism of spin-lattice relaxation of FLF fluorine atoms does not change with temperature. The tauc value for solid dispersions containing 20% PVP was 2-3 times longer than that for solid dispersions containing 20% HPMC at 50 degrees C, indicating that the molecular mobility of FLF in solid dispersions containing 20% PVP was lower than that in solid dispersions containing 20% HPMC. The amount of amorphous FLF remaining in the solid dispersions stored at 60 degrees C was successfully estimated by analyzing the solid echo signals of FLF fluorine atoms, and it was possible to follow the overall crystallization of amorphous FLF in the solid dispersions. The solid dispersion containing 20% PVP was more stable than that containing 20% HPMC. The difference in stability between solid dispersions containing PVP and HPMC is considered due to the difference in molecular mobility as determined by tauc. The molecular mobility determined by 19F-NMR seems to be a useful measure for assessing the stability of drugs containing fluorine atoms in amorphous solid dispersions.

  4. Linear and nonlinear optical susceptibilities in a laterally coupled quantum-dot–quantum-ring system

    Zeng, Zaiping; Garoufalis, Christos S.; Baskoutas, Sotirios, E-mail:


    Linear and nonlinear optical susceptibilities in a laterally coupled quantum-dot–quantum-ring system have been theoretically studied. In general, we find that the structure parameters of the coupled system significantly affect the optical susceptibilities. The enhancement of the coupling effects between the dot and ring is found to increase considerably the optical susceptibilities and redshift drastically the transition energies. Comparing to the linear susceptibility, the nonlinear optical susceptibility is found to be more sensitive to the variation of the structure parameters. A comprehensive analysis of the electron probability density movement with respect to the modification of the structure parameters is provided, which offers a unique perspective of the ground-state localization. - Highlights: • Optical susceptibilities in a quantum-dot–quantum-ring system are studied. • The structure parameters significantly affect the optical susceptibilities. • The enhancement of the coupling effects increases the optical susceptibilities. • The nonlinear susceptibility is more sensitive to the change in structure parameters. • A comprehensive analysis of the electron probability density movement is provided.

  5. Constraints on the size and dynamics of the J1407b ring system

    Rieder, Steven


    Context. J1407 (1SWASP J140747.93-394542.6 in full) is a young star in the Scorpius-Centaurus OB association that underwent a series of complex eclipses over 56 days in 2007. In a series of articles, Mamajek et al. (2012) and others hypothesised that a secondary substellar companion, J1407b, has a giant ring system filling a large fraction of the Hill sphere, causing the eclipses. Observations have not successfully detected J1407b, but do rule out circular orbits for the companion around the primary star. Aims. We test to what degree the ring model of J1407b could survive in an eccentric orbit required to fit the observations. Methods. We run N-body simulations under the AMUSE framework to test the stability of Hill radius-filling systems where the companion is on an eccentric orbit. Results. We strongly rule out prograde ring systems and find that a secondary of 60 to 100MJup with an 11 year orbital period and retrograde orbiting material can survive for at least $10^4$ orbits and produce eclipses with simil...

  6. Constraints on the size and dynamics of the J1407b ring system

    Rieder, Steven; Kenworthy, Matthew A.


    Context. J1407 (1SWASP J140747.93-394542.6 in full) is a young star in the Scorpius-Centaurus OB association that underwent a series of complex eclipses over 56 days in 2007. To explain these, it was hypothesised that a secondary substellar companion, J1407b, has a giant ring system filling a large fraction of the Hill sphere, causing the eclipses. Observations have not successfully detected J1407b, but do rule out circular orbits for the companion around the primary star. Aims: We test to what degree the ring model of J1407b could survive in an eccentric orbit required to fit the observations. Methods: We run N-body simulations under the AMUSE framework to test the stability of Hill radius-filling systems where the companion is on an eccentric orbit. Results: We strongly rule out prograde ring systems and find that a secondary of 60 to 100 MJup with an 11 yr orbital period and retrograde orbiting material can survive for at least 104 orbits and produce eclipses with similar durations as the observed one.

  7. Commissioning and Early Operation Experience of the NSLS-II Storage Ring RF System

    Gao, F.; Rose, J.; Cupolo, J.; Dilgen, T.; Rose, B.; Gash, W.; Ravindranath, V.; Yeddulla, M.; Papu, J.; Davila, P.; Holub, B.; Tagger, J.; Sikora, R.; Ramirez, G.; Kulpin, J.


    The National Synchrotron Light Source II (NSLS-II) is a 3 GeV electron X-ray user facility commissioned in 2014. The storage ring RF system, essential for replenishing energy loss per turn of the electrons, consists of digital low level RF controllers, 310 kW CW klystron transmitters, CESR-B type superconducting cavities, as well as a supporting cryogenic system. Here we will report on RF commissioning and early operation experience of the system for beam current up to 200mA.

  8. Monitor and control systems for the SLD Cherenkov Ring Imaging Detector

    Antilogus, P.; Aston, D.; Bienz, T.; Bird, F.; Dasu, S.; Dunwoodie, W.; Fernandez, F.; Hallewell, G.; Kawahara, H.; Korff, P.; Kwon, Y.; Leith, D.; Muller, D.; Nagamine, T.; Pavel, T.; Rabinowitz, L.; Ratcliff, B.; Rensing, P.; Schultz, D.; Shapiro, S.; Simopoulos, C.; Solodov, E.; Toge, N.; Va' Vra, J.; Williams, S.; Whitaker, J.; Wilson, R.J.; Bean, A.; Caldwell, D.; Duboscq, J.; Huber, J.; Lu, A.; McHugh, S.; Mathys, L.; Morriso


    To help ensure the stable long-term operation of a Cherenkov Ring Detector at high efficiency, a comprehensive monitor and control system is being developed. This system will continuously monitor and maintain the correct operating temperatures, and will provide an on-line monitor and maintain the correct operating temperatures, and will provide an on-line monitor of the pressures, flows, mixing, and purity of the various fluids. In addition the velocities and trajectories of Cherenkov photoelectrons drifting within the imaging chambers will be measured using a pulsed uv lamp and a fiberoptic light injection system. 9 refs., 6 figs.

  9. Token Ring Algorithm To Achieve Mutual Exclusion In Distributed System - A Centralized Approach

    Sandipan Basu


    Full Text Available This paper presents an algorithm for achieving mutual exclusion in Distributed System. The proposed algorithm is a betterment of the already existing Token Ring Algorithm, used to handle mutual exclusion in Distributed system. In the already existing algorithm, there are few problems, which, if occur during process execution, then the distributed system will not be able to ensure mutual exclusion among the processes and consequently unwanted situations may arise. The proposed algorithm will overcome all the problems in the existing algorithm, and ensures mutual exclusion among the processes, when they want to execute in their critical section of code.

  10. Overview of Electrical Systems for the University of Maryland Electron Ring (UMER)

    Quinn, Bryan; Bernal, Santiago; Godlove, Terry; Haber, Irving; Harris, John R; Holloway, Mike; Li, Hui; Neumann, Jonathan G; Reiser, Martin; Tian, Kai; Walter, Mark


    Commissioning of the University of Maryland Electron Ring (UMER) is underway (see general abstract on UMER). We discuss the various electrical systems of UMER. The power system includes 114 supplies for 70 air-core magnetic quadrupoles, 36 bending dipoles and 30+ steering dipoles as well as earth's field compensating coils. Systems for data collection comprise multiplexers and fast digitizers for diagnostics including 15 fast beam position monitors (BPMs)and video capture from fluorescent screen monitors. Several pulsers have been built in-house for injection and extraction magnets. The stringent timing schemes are also presented.

  11. ALS Booster Ring RF System Upgrade for Top-Off Mode of Operation

    Kwiatkowski, Slawomir


    ALS is one of the first third generation synchrotron light sources which has been operating since 1993 at Berkeley Lab. In the present ALS operation scenario 1.5GeV electron beam is injected from the booster into the storage ring every 8 hours where is accelerated to the final energy of 1.9GeV. The beam decays between fills from 400mA to 200mA with the time average current of 250mA. In order to increase the beam brighthess ALS team plans to increase the beam current to 500mA and maintain it constant during machine operation ("Top-Off" mode of operation). This operation scenario will require full energy injection from the booster ring into the storage ring and constant operation of the injector (10 bunches with the total charge of 1nC every 30 to 35 seconds). In this paper we will present the results of the ALS injector RF system analysis fo Top-Off mode of operation and describe the way we intent to implement the necessary modifications to the booster RF system.

  12. James Webb Space Telescope Observations of Stellar Occultations by Solar System Bodies and Rings

    Santos-Sanz, P.; French, R. G.; Pinilla-Alonso, N.; Stansberry, J.; Lin, Z-Y.; Zhang, Z-W.; Vilenius, E.; Mueller, Th.; Ortiz, J. L.; Braga-Ribas, F.; hide


    In this paper, we investigate the opportunities provided by the James Webb Space Telescope (JWST) for significant scientific advances in the study of Solar System bodies and rings using stellar occultations. The strengths and weaknesses of the stellar occultation technique are evaluated in light of JWST's unique capabilities. We identify several possible JWST occultation events by minor bodies and rings and evaluate their potential scientific value. These predictions depend critically on accurate a priori knowledge of the orbit of JWST near the Sun–Earth Lagrange point 2 (L2). We also explore the possibility of serendipitous stellar occultations by very small minor bodies as a byproduct of other JWST observing programs. Finally, to optimize the potential scientific return of stellar occultation observations, we identify several characteristics of JWST's orbit and instrumentation that should be taken into account during JWST's development.

  13. JWST observations of stellar occultations by solar system bodies and rings

    Santos-Sanz, P; Pinilla-Alonso, N; Stansberry, J; Lin, Z-Y; Zhang, Z-W; Vilenius, E; Müller, Th; Ortiz, J L; Braga-Ribas, F; Bosh, A; Duffard, R; Lellouch, E; Tancredi, G; Young, L


    In this paper we investigate the opportunities provided by the James Webb Space Telescope (JWST) for significant scientific advances in the study of solar system bodies and rings using stellar occultations. The strengths and weaknesses of the stellar occultation technique are evaluated in light of JWST's unique capabilities. We identify several possible JWST occultation events by minor bodies and rings, and evaluate their potential scientific value. These predictions depend critically on accurate a priori knowledge of the orbit of JWST near the Sun-Earth Lagrange-point 2 (L2). We also explore the possibility of serendipitous stellar occultations by very small minor bodies as a by-product of other JWST observing programs. Finally, to optimize the potential scientific return of stellar occultation observations, we identify several characteristics of JWST's orbit and instrumentation that should be taken into account during JWST's development.

  14. Experimental study of radiative pion capture on /sup 13/C, /sup 20/Ne, /sup 90/Zr, /sup 19/F and /sup 12/C

    Martoff, C.J.


    Photon spectra for 50 < E/sub ..gamma../ < 135 MeV have been measured from the radiative capture of stopped negative pions by the nuclides /sup 13/C, /sup 19/F, /sup 20/Ne, and /sup 90/Zr. The e/sup +/e/sup -/ pair spectrometer system used has resolution 850 keV fwhm and photon detection efficiency 5 x 10/sup -6/. The total radiative capture branching ratios measured are /sup 13/C (1.66 +- 0.25)%, /sup 19/F (2.40 +- 0.48)%, /sup 20/Ne (1.60 +- 0.24)%, and /sup 90/Zr (2.1 +- 0.5)%. The partial radiative capture branching ratios to four bound states and two resonances in /sup 20/F, and two bound states and three resonances in /sup 13/B have also been measured. The branching ratio for /sup 13/C(..pi../sup -/,..gamma..)/sup 13/B g.s. is (6.1 +- 1.2) x 10/sup -4/. Comparison of this result with the beta decay rate of /sup 13/B shows that (84 +- 16)% of the pion capture amplitude is accounted for by the Gamow-Teller matrix element. Further analysis suggests that much of the remaining strength is E2. The measured branching ratios to resonant states in /sup 13/C(..pi../sup -/,..gamma..)/sup 13/B are shown to be in agreement with detailed shell model calculations. The total single-particle strength in these transitions is shown to be approximately half as large as that of the T = 3/2 part of the E1 photoresonance (the Giant Dipole Resonance) in /sup 13/C. The branching ratio for /sup 20/Ne(..pi../sup -/,..gamma..)/sup 20/F (T = 1, J/sup ..pi../ = 1/sup +/, E/sub x/ = 1.06 MeV) is 0.91 +- 0.52).10/sup -4/. Comparison with the electroexcitation of the analog giant M1 state in /sup 20/Ne (11.24 MeV) shows that the M1 transition amplitude is less than (46 +- 14)% Gamow-Teller. This result is in agreement with detailed shell model calculations of the M1 transition. The photon spectrum for radiative pion capture from flight (reaction /sup 12/C(..pi../sup +/ T = 44 MeV, ..gamma.. at 90/sup 0/)) has been measured. 13 figures, 12 tables.

  15. Design of the beam transport line and injection system of the compact storage ring for TTX


    In this article, we present the design of the beam transport line and injection system of the compact storage ring for the Tsinghua Thomson scattering X-ray (TTX) source. The layout of the beam transport line fits in with the limited available space. The injection system is simplified, consisting of only one single kicker; the stray field on the reference orbit is also reduced without the septum magnet. We choose a travelling wave kicker and present both 2D and 3D simulations for the structure design.

  16. The Spectral Classes of the Saturnian System Ices: Rings and Satellites Observations by Cassini-VIMS

    Filacchione, G.; Capaccioni, F.; Tosi, F.; Coradini, A.; Cerroni, P.; Clark, R. N.; Cuzzi, J. N.; Nicholson, P. D.; Buratti, B. J.; Brown, R. H.; Cruikshank, D. P.; Jaumann, R.; Hedman, M. M.


    The entire population of the Saturnian system ices was investigated by VIMS (Visual and Infrared Mapping Spectrometer) experiment on board Cassini spacecraft. By the end of the nominal mission a very large dataset of hyperspectral data had been collected in the spectral range 0.35-5.0 micron, which includes the regular satellites (Mimas, Enceladus, Tethys, Dione, Rhea, Hyperion, Iapetus, Phoebe), minor moons (Atlas, Prometheus, Pandora, Janus, Epimetheus, Telesto, Calypso) and rings. In this work we present an analysis of spectrophotometric indicators selected to describe the properties of the ices (I/F continuum levels, visible spectral slopes, band depths and positions), and which were retrieved from about 1500 full-disk observations of satellites as well as from mosaics of the main rings (A, B, C, CD, F) sampled with a resolution of 125 km/pixel along the radial axis. This comparative method allows us to highlight the spectral differences in this population of objects orbiting in the Saturnian system. In particular we have retrieved the distribution of the water ice abundance, which varies between the almost pure icy surfaces of Enceladus and Calypso to the carbon dioxide- and organic-rich Hyperion, Iapetus and Phoebe. Noteworthy is that a significant dichotomy is observed between the two co-orbital moons Epimetheus and Janus, possibly indicating a different origin and evolutionary process: while the first shows a very red visible spectrum (similar to Hyperion), the second has more neutral visible colors, making it a very peculiar object in the Saturnian system. Rings have very peculiar spectral differences when compared with the icy satellites: in the visible range their spectra are characterized by a spectral knee at bluer wavelengths (at about 520 nm compared to 550 nm on satellites); in the infrared range the 1.5-2.0 micron water ice band depths are in general deeper across the A and B rings, indicative of a larger fraction of pure water ice in comparison to

  17. Ballistic transport in planetary ring systems due to particle erosion mechanisms. I - Theory, numerical methods, and illustrative examples

    Durisen, Richard H.; Murphy, Brian W.; Cramer, Nichael Lynn; Cuzzi, Jeffrey N.; Mullikin, Thomas L.


    Ballistic transport, defined as the net radial transport of mass and angular momentum due to exchanges of meteoroid hypersonic-impact ejecta by neighboring planetary ring regions on time-scales orders-of-magnitude shorter than the age of the solar system, is presently considered as a problem in mathematical physics. The preliminary results of a numerical scheme for following the combined effects of ballistic transport and viscous diffusion demonstrate that ballistic transport generates structure near sharp edges already present in the ring-mass distribution; the entire ring system ultimately develops an undulatory structure whose length scale is typically of the order of the radial excursion of the impact ejecta.

  18. Design considerations for a digital feedback system to control self-bunching in ion-storage rings

    V. Ziemann


    Full Text Available We discuss the feasibility of a digital feedback system to cure self-bunching of the electron-cooled coasting ion beam in ion-storage rings such as CELSIUS [S. Holm, A. Johansson, S. Kullander, and D. Reistad, Phys. Scr. 34, 513–532 (1986]. Such a system is based on a fast digital filter that acts as a tunable artificial wake potential. It may also aid stable operation of accumulator rings for future spallation neutron sources or heavy ion rings used for inertial fusion energy production.

  19. Variable diameter CO2 laser ring-cutting system adapted to a zoom microscope for applications on polymer tapes.

    Förster, Erik; Bohnert, Patrick; Kraus, Matthias; Kilper, Roland; Müller, Ute; Buchmann, Martin; Brunner, Robert


    This paper presents the conception and implementation of a variable diameter ring-cutting system for a CO2 laser with a working wavelength of 10.6 μm. The laser-cutting system is adapted to an observation zoom microscope for combined use and is applicable for the extraction of small circular areas from polymer films, such as forensic adhesive tapes in a single shot. As an important characteristic for our application, the variable diameter ring-cutting system provides telecentricity in the target area. Ring diameters are continuously tunable between 500 μm and 2 mm. A minimum width of less than 20 μm was found for the ring profile edge. The basic characteristics of the system, including telecentricity, were experimentally evaluated and demonstrated by cutting experiments on different polymer tapes and further exemplary samples.

  20. 19F+27Al耗散反应产物截面测量中的不重复性%Non-reproducibility of the Cross Sections of the Products Induced from Dissipative Reaction of 19F+27Al

    韩建龙; 王琦; 董玉川; 李松林; 段利敏; 吴和宇; 徐华根; 陈若富; 徐瑚珊; 白真; 李志常; 路秀琴; 赵葵; 周平; 刘建成; 许国基; Sergey; Yu; Kun




    Michał MATOWICKI


    Full Text Available Many previous studies have confirmed the strong relationship between speed compliance and the frequency and severity of traffic accidents. Variable speed limit (VSL system as a measure to improve traffic safety enables the freeway system to change its posted speed limit based on various traffic and environmental conditions. Such system helps drivers to recognize the upcoming events, to adjust their driving style and in such way to address speed variation of the traffic flow. This is called speed harmonization. Although many studies researching the effect of VSL system on the traffic stream can be found, there are only few addressing its influence on the drivers behavior, particularly focusing on their tolerance limit and compliance, which has crucial meaning for future design of controlling algorithms. This study was prepared to inspect this grey area by studying the data from the VSL system at Prague city ring, describing the influence of the highway management system and its influence on drivers.

  2. A Performance Comparison of Tree and Ring Topologies in Distributed System

    Huang, Min [Iowa State Univ., Ames, IA (United States)


    A distributed system is a collection of computers that are connected via a communication network. Distributed systems have become commonplace due to the wide availability of low-cost, high performance computers and network devices. However, the management infrastructure often does not scale well when distributed systems get very large. Some of the considerations in building a distributed system are the choice of the network topology and the method used to construct the distributed system so as to optimize the scalability and reliability of the system, lower the cost of linking nodes together and minimize the message delay in transmission, and simplify system resource management. We have developed a new distributed management system that is able to handle the dynamic increase of system size, detect and recover the unexpected failure of system services, and manage system resources. The topologies used in the system are the tree-structured network and the ring-structured network. This thesis presents the research background, system components, design, implementation, experiment results and the conclusions of our work. The thesis is organized as follows: the research background is presented in chapter 1. Chapter 2 describes the system components, including the different node types and different connection types used in the system. In chapter 3, we describe the message types and message formats in the system. We discuss the system design and implementation in chapter 4. In chapter 5, we present the test environment and results, Finally, we conclude with a summary and describe our future work in chapter 6.

  3. Design, Modeling and Control of Magnetic Bearings for a Ring-Type Flywheel Energy Storage System

    Chow-Shing Toh


    Full Text Available This study is concerned with the magnetic force models of magnetic bearing in a flywheel energy storage system (FESS. The magnetic bearing is of hybrid type, with axial passive magnetic bearing (PMB and radial hybrid magnetic bearing (HMB. For the PMB, a pair of ring-type Halbach arrays of permanent magnets are arranged vertically to support the rotor weight. For the HMB, a set of ring-type Halbach array is placed on the rotor side, which corresponds to coil sets on the stator side. The HMB can produce both attraction and repulsion forces on the radial direction, depending on the direction of the coil currents. It is found that the ring-type configuration and the differential winding scheme for coil sets can yield linear magnetic force models for both PMB and HMB. Based on the obtained magnetic force model, an integral sliding mode controller is designed for the stable rotor levitation in the radial direction. The experimental results show that the rotor can be stabilized to the bearing center, verifying the accuracy of the magnetic force models and effectiveness of the levitation controller.

  4. Forbidden Coherence Transfer of 19F Nuclei to Quantitatively Measure the Dynamics of a CF3-Containing Ligand in Receptor-Bound States

    Yuji Tokunaga


    Full Text Available The dynamic property of a ligand in the receptor-bound state is an important metric to characterize the interactions in the ligand–receptor interface, and the development of an experimental strategy to quantify the amplitude of motions in the bound state is of importance to introduce the dynamic aspect into structure-guided drug development (SGDD. Fluorine modifications are frequently introduced at the hit-to-lead optimization stage to enhance the binding potency and other characteristics of a ligand. However, the effects of fluorine modifications are generally difficult to predict, owing to the pleiotropic nature of the interactions. In this study, we report an NMR-based approach to experimentally evaluate the local dynamics of trifluoromethyl (CF3-containing ligands in the receptor-bound states. For this purpose, the forbidden coherence transfer (FCT analysis, which has been used to study the dynamics of methyl moieties in proteins, was extended to the 19F nuclei of CF3-containing ligands. By applying this CF3–FCT analysis to a model interaction system consisting of a ligand, AST-487, and a receptor, p38α, we successfully quantified the amplitude of the CF3 dynamics in the p38α-bound state. The strategy would bring the CF3-containing ligands within the scope of dynamic SGDD to improve the affinity and specificity for the drug-target receptors.

  5. Verification of threshold activation detection (TAD) technique in prompt fission neutron detection using scintillators containing 19F

    Sibczynski, P.; Kownacki, J.; Moszyński, M.; Iwanowska-Hanke, J.; Syntfeld-Każuch, A.; Gójska, A.; Gierlik, M.; Kaźmierczak, Ł.; Jakubowska, E.; Kędzierski, G.; Kujawiński, Ł.; Wojnarowicz, J.; Carrel, F.; Ledieu, M.; Lainé, F.


    In the present study ⌀ 5''× 3'' and ⌀ 2''× 2'' EJ-313 liquid fluorocarbon as well as ⌀ 2'' × 3'' BaF2 scintillators were exposed to neutrons from a 252Cf neutron source and a Sodern Genie 16GT deuterium-tritium (D+T) neutron generator. The scintillators responses to β- particles with maximum endpoint energy of 10.4 MeV from the n+19F reactions were studied. Response of a ⌀ 5'' × 3'' BC-408 plastic scintillator was also studied as a reference. The β- particles are the products of interaction of fast neutrons with 19F which is a component of the EJ-313 and BaF2 scintillators. The method of fast neutron detection via fluorine activation is already known as Threshold Activation Detection (TAD) and was proposed for photofission prompt neutron detection from fissionable and Special Nuclear Materials (SNM) in the field of Homeland Security and Border Monitoring. Measurements of the number of counts between 6.0 and 10.5 MeV with a 252Cf source showed that the relative neutron detection efficiency ratio, defined as epsilonBaF2 / epsilonEJ-313-5'', is 32.0% ± 2.3% and 44.6% ± 3.4% for front-on and side-on orientation of the BaF2, respectively. Moreover, the ⌀ 5'' EJ-313 and side-on oriented BaF2 were also exposed to neutrons from the D+T neutron generator, and the relative efficiency epsilonBaF2 / epsilonEJ-313-5'' was estimated to be 39.3%. Measurements of prompt photofission neutrons with the BaF2 detector by means of data acquisition after irradiation (out-of-beam) of nuclear material and between the beam pulses (beam-off) techniques were also conducted on the 9 MeV LINAC of the SAPHIR facility.

  6. Modeling giant extrasolar ring systems in eclipse and the case of J1407b: sculpting by exomoons?

    Kenworthy, Matthew A


    The light curve of 1SWASP J140747.93-394542.6, a $\\sim$16 Myr old star in the Sco-Cen OB association, underwent a complex series of deep eclipses that lasted 56 days, centered on April 2007. This light curve is interpreted as the transit of a giant ring system that is filling up a fraction of the Hill sphere of an unseen secondary companion, J1407b. We fit the light curve with a model of an azimuthally symmetric ring system, including spatial scales down to the temporal limit set by the star's diameter and relative velocity. The best ring model has 37 rings and extends out to a radius of 0.6 AU (90 million km), and the rings have an estimated total mass on the order of $100 M_{Moon}$. The ring system has one clearly defined gap at 0.4 AU (61 million km), which we hypothesize is being cleared out by a $< 0.8 M_{\\oplus}$ exosatellite orbiting around J1407b. This eclipse and model implies that we are seeing a circumplanetary disk undergoing a dynamic transition to an exosatellite-sculpted ring structure and i...

  7. Cross-Correlation of Excitation Functions for Different Fragments and Different Scattering Angles in 27Al(19F, x) y Reactions

    HAN Jian-Long; WU He-Yu; LI Zhi-Chang; LU Xiu-Qin; ZHAO Kui; ZHOU Ping; LIU Jian-Cheng; XU Guo-Ji; Sergey Yu Kun; WANG Qi; BAI Zhen; DONG Yu-Chuan; LI Song-Lin; DUAN Li-Min; XU Hu-Shan; XU Hua-Gen; CHEN Ruo-Fu


    @@ Excitation functions have been measured for different projectile-like fragments produced in 27 Al(19 F,x)y reactions at incident energies from 110.25 to 118. 75 Me V in 250 ke V steps. Strong cross section fluctuations of the excitation functions are observed. The cross-correlation coefficients of the excitation functions for different atomic number Z and for different scattering angle θcm have been deduced. These coefficients are much larger than the statistical theoretical calculated ones. This indicates that there are strong correlations between different exit channels in the dissipative heavy ion collision of 27 Al(19 F,x )y.

  8. Universal cumulants of the current in diffusive systems on a ring

    Appert-Rolland, C.; Derrida, B.; Lecomte, V.; van Wijland, F.


    We calculate exactly the first cumulants of the integrated current and of the activity (which is the total number of changes of configurations) of the symmetric simple exclusion process on a ring with periodic boundary conditions. Our results indicate that for large system sizes the large deviation functions of the current and of the activity take a universal scaling form, with the same scaling function for both quantities. This scaling function can be understood either by an analysis of Bethe ansatz equations or in terms of a theory based on fluctuating hydrodynamics or on the macroscopic fluctuation theory of Bertini, De Sole, Gabrielli, Jona-Lasinio, and Landim.

  9. Synthesis and Thermal Behavior of a Fused, Tricyclic 1,2,3,4-Tetrazine Ring System.

    Chavez, David E; Bottaro, Jeffery C; Petrie, Mark; Parrish, Damon A


    This study presents the synthesis and characterization of a fused, tricyclic 1,2,3,4-tetrazine ring system. The molecule is synthesized in a three-step process from 5,5'-dinitro-bis,1,2,4-triazole via a di-N-amino compound. Oxidation to form the azo-coupled fused tricyclic 1,2,3,4-tetrazine is achieved using tert-butyl hypochlorite as the oxidant. The di-N-amino compound and the desired fused tricyclic 1,2,3,4-triazine display interesting thermal behavior and are predicted to be high-performance energetic materials.

  10. Error Modeling, Calibration, and Nonlinear Interpolation Compensation Method of Ring Laser Gyroscope Inertial Navigation System

    Jianli Li


    Full Text Available In order to improve the precision of Strapdown Inertial Navigation System (SINS and reduce the complexity of the traditional calibration method, a novel calibration and compensation scheme is proposed. An optimization calibration method with four-direction rotations is designed to calculate all error coefficients of Ring Laser Gyroscope (RLG SINS in a series of constant temperatures. According to the actual working environment, the temperature errors of RLG SINS are compensated by a nonlinear interpolation compensation algorithm. The experimental results show that the inertial navigation errors of the proposed method are reduced.

  11. Multicomponent reactions for synthesis of bioactive polyheterocyclic ring systems under controlled microwave irradiation

    Eman M.H. Abbas


    Full Text Available The multi-component reaction of 1-benzothiopyran-4-ones with heterocyclic amines and dimethylformamide-dimethylacetal (DMFDMA in DMF at 150 °C under controlled microwave heating afforded novel poly-heterocyclic ring systems. Also, reaction of 3-dimethylaminomethylene-1-benzothiopyran-4-one with activemethylene derivatives was investigated. The structure of all products was established on the bases of spectral data and elemental analyses and alternative synthesis if possible. The prepared compounds were screened for their antitumor activity against HCT-116 “colon” cancer cell line and some derivatives showed promising activity.

  12. Molecular structure, interatomic interactions and vibrational analysis of 1,4-diazabicyclo[3.2.1]octane parent ring system

    Britvin, Sergey N.; Rumyantsev, Andrey M.; Zobnina, Anastasia E.; Padkina, Marina V.


    Molecular structure of 1,4-diazabicyclo[3.2.1]octane, a parent ring of TAN1251 family of alkaloids, is herein characterized for the first time in comparison with the structure of nortropane (8-azabicyclo[3.2.1]octane), the parent framework of tropane ring system. The methods of study involve X-ray structural analysis, DFT geometry optimizations with infrared frequency calculations followed by natural bond orbital (NBO) analysis, and vibrational analysis of infrared spectrum.

  13. The trigger system for the external target experiment in the HIRFL cooling storage ring

    Li, Min; Zhao, Lei; Liu, Jin-Xin; Lu, Yi-Ming; Liu, Shu-Bin; An, Qi


    A trigger system was designed for the external target experiment in the Cooling Storage Ring (CSR) of the Heavy Ion Research Facility in Lanzhou (HIRFL). Considering that different detectors are scattered over a large area, the trigger system is designed based on a master-slave structure and fiber-based serial data transmission technique. The trigger logic is organized in hierarchies, and flexible reconfiguration of the trigger function is achieved based on command register access or overall field-programmable gate array (FPGA) logic on-line reconfiguration controlled by remote computers. We also conducted tests to confirm the function of the trigger electronics, and the results indicate that this trigger system works well. Supported by the National Natural Science Foundation of China (11079003), the Knowledge Innovation Program of the Chinese Academy of Sciences (KJCX2-YW-N27), and the CAS Center for Excellence in Particle Physics (CCEPP).

  14. The Ring of Fire - an internal illimination system for detector sensitivity and filter bandpass characterization

    Scarpine, Victor E.; Kent, Stephen M.; /Fermilab; Deustua, Susana E.; /Baltimore, Space Telescope Sci.; Sholl, Michael J.; /LBL, Berkeley; Mufson, Stuart L.; /Indiana U.; Ott, Melanie N.; /NASA, Goddard; Wiesner, Matthew P.; /Northern Illinois U.; Baptitst, Brian J.; /Indiana U.


    We describe a prototype of an illumination system, the Ring of Fire (ROF), which is used as part of an internal calibration system for large focal plane detector arrays in TMA (Three Mirror Anastigmat) telescope designs. Such designs have been proposed for the SNAP (SuperNova Acceleration Probe) version of a Joint Dark Energy Mission (JDEM). The ROF system illuminates the focal plane with a light beam the closely matches that of the telescope and is used for creating high spatial frequency flat fields and monitoring filter bandpasses for experiments that demand a highly accurate characterization of the detectors. We present measurements of a mockup of this prototype ROF design including studies in variations in illumination across a large focal plane.

  15. Klystron 'efficiency loop' for the ALS storage ring RF system

    Kwiatkowski, Slawomir; Julian, Jim; Baptiste, Kenneth


    The recent energy crisis in California has led us to investigate the high power RF systems at the Advanced Light Source (ALS) in order to decrease the energy consumption and power costs. We found the Storage Ring Klystron Power Amplifier system operating as designed but with significant power waste. A simple proportional-integrator (PI) analog loop, which controls the klystron collector beam current, as a function of the output RF power, has been designed and installed. The design considerations, besides efficiency improvement, were to interface to the existing system without major expense. They were to also avoid the klystron cathode power supply filter's resonance in the loop's dynamics, and prevent a conflict with the existing Cavity RF Amplitude Loop dynamics. This efficiency loop will allow us to save up to 700 MW-hours of electrical energy per year and increase the lifetime of the klystron.

  16. Direct mapping of 19F in 19FDG-6P in brain tissue at subcellular resolution using soft X-ray fluorescence

    Poitry-Yamate, C.; Gianoncelli, A.; Kourousias, G.; Kaulich, B.; Lepore, M.; Gruetter, R.; Kiskinova, M.


    Low energy x-ray fluorescence (LEXRF) detection was optimized for imaging cerebral glucose metabolism by mapping the fluorine LEXRF signal of 19F in 19FDG, trapped as intracellular 19F-deoxyglucose-6-phosphate (19FDG-6P) at 1μm spatial resolution from 3μm thick brain slices. 19FDG metabolism was evaluated in brain structures closely resembling the general cerebral cytoarchitecture following formalin fixation of brain slices and their inclusion in an epon matrix. 2-dimensional distribution maps of 19FDG-6P were placed in a cytoarchitectural and morphological context by simultaneous LEXRF mapping of N and O, and scanning transmission x-ray (STXM) imaging. A disproportionately high uptake and metabolism of glucose was found in neuropil relative to intracellular domains of the cell body of hypothalamic neurons, showing directly that neurons, like glial cells, also metabolize glucose. As 19F-deoxyglucose-6P is structurally identical to 18F-deoxyglucose-6P, LEXRF of subcellular 19F provides a link to in vivo 18FDG PET, forming a novel basis for understanding the physiological mechanisms underlying the 18FDG PET image, and the contribution of neurons and glia to the PET signal.

  17. (1)H and (19)F spin-lattice relaxation and CH3 or CF3 reorientation in molecular solids containing both H and F atoms.

    Beckmann, Peter A; Rheingold, Arnold L


    The dynamics of methyl (CH3) and fluoromethyl (CF3) groups in organic molecular (van der Waals) solids can be exploited to survey their local environments. We report solid state (1)H and (19)F spin-lattice relaxationexperiments in polycrystalline 3-trifluoromethoxycinnamic acid, along with an X-ray diffraction determination of the molecular and crystal structure, to investigate the intramolecular and intermolecular interactions that determine the properties that characterize the CF3 reorientation. The molecule is of no particular interest; it simply provides a motionless backbone (on the nuclear magnetic resonance(NMR) time scale) to investigate CF3 reorientation occurring on the NMR time scale. The effects of (19)F-(19)F and (19)F-(1)H spin-spin dipolar interactions on the complicated nonexponential NMRrelaxation provide independent inputs into determining a model for CF3 reorientation. As such, these experiments provide much more information than when only one spin species (usually (1)H) is present. In Sec. IV, which can be read immediately after the Introduction without reading the rest of the paper, we compare the barrier to CH3 and CF3 reorientation in seven organic solids and separate this barrier into intramolecular and intermolecular components.

  18. Calculation of vibrational branching ratios and hyperfine structure of 24Mg19F and its suitability for laser cooling and magneto-optical trapping

    Xu, Liang; Yin, Yanning; Wei, Bin; Xia, Yong; Yin, Jianping


    More recently, laser cooling of the diatomic radical magnesium monofluoride (24Mg19F ) is being experimentally preformed [Appl. Phys. Express 8, 092701 (2015), 10.7567/APEX.8.092701 and Opt. Express 22, 28645 (2014), 10.1364/OE.22.028645] and was also studied theoretically [Phys. Rev. A 91, 042511 (2015), 10.1103/PhysRevA.91.042511]. However, some important problems still remain unsolved, so, in our paper, we perform further theoretical study for the feasibility of laser cooling and trapping the 24Mg19F molecule. At first, the highly diagonal Franck-Condon factors of the main transitions are verified by the closed-form approximation, Morse approximation, and Rydberg-Klein-Rees inversion methods, respectively. Afterwards, we investigate the lower X 2Σ1/2 + hyperfine manifolds using a quantum effective Hamiltonian approach and obtain the zero-field hyperfine spectrum with an accuracy of less than 30 kHz ˜5 μ K compared with the experimental results, and then find out that one cooling beam and one or two repumping beams with their first-order sidebands are enough to implement an efficient laser slowing and cooling of 24Mg19F . Meanwhile, we also calculate the accurate hyperfine structure magnetic g factors of the rotational state (X 2Σ1/2 +,N =1 ) and briefly discuss the influence of the external fields on the hyperfine structure of 24Mg19F as well as its possibility of preparing three-dimensional magneto-optical trapping. Finally we give an explanation for the difference between the Stark and Zeeman effects from the perspective of parity and time reversal symmetry. Our study shows that, besides appropriate excitation wavelengths, the short lifetime for the first excited state A 2Π1 /2 , and lighter mass, the 24Mg19F radical could be a good candidate molecule amenable to laser cooling and magneto-optical trapping.

  19. Structural investigation of α-LaZr2F11 by coupling X-ray powder diffraction, 19F solid state NMR and DFT calculations

    Martineau, Charlotte; Legein, Christophe; Body, Monique; Péron, Olivier; Boulard, Brigitte; Fayon, Franck


    α-LaZr2F11 has been synthesized by solid state reaction. Its crystal structure has been refined from X-ray powder diffraction data (space group no. 72 Ibam, a=7.785(1) Å, b=10.086(1) Å and c=11.102(1) Å). α-LaZr2F11 contains one La, one Zr and four F inequivalent crystallographic sites. F3 and F4 are shared between one ZrF73- polyhedron and one LaF85- polyhedron, while F1 and F2 bridge two ZrF73- polyhedra. 19F 1D MAS NMR spectra of α-LaZr2F11 are in agreement with the proposed structural model. Assignment of the 19F resonances to the corresponding crystallographic sites has been performed on the basis of both their relative intensities and their correlation patterns in a 19F 2D dipolar-based double-quantum recoupling MAS NMR spectrum. DFT calculations of the 19F chemical shielding tensors have been performed using the GIPAW method implemented in the NMR-CASTEP code, for the experimental structure and two PBE-DFT geometry optimized structures of α-LaZr2F11 (atomic position optimization and full geometry optimization with rescaling of the unit cell volume to the experimental value). Computations were done with and without using a modified La pseudopotential allowing the treatment of the 4f localized empty orbitals of La3+. A relatively nice agreement between the experimental 19F isotropic and anisotropic chemical shifts and the values calculated for the proposed structural model is obtained.

  20. Optical Analog to Electromagnetically Induced Transparency in Cascaded Ring-Resonator Systems

    Wang, Yonghua; Zheng, Hua; Xue, Chenyang; Zhang, Wendong


    The analogue of electromagnetically induced transparency in optical methods has shown great potential in slow light and sensing applications. Here, we experimentally demonstrated a coupled resonator induced transparency system with three cascaded ring coupled resonators in a silicon chip. The structure was modeled by using the transfer matrix method. Influences of various parameters including coupling ratio of couplers, waveguide loss and additional loss of couplers on transmission characteristic and group index have been investigated theoretically and numerically in detail. The transmission character of the system was measured by the vertical grating coupling method. The enhanced quality factor reached 1.22 × 105. In addition, we further test the temperature performance of the device. The results provide a new method for the manipulation of light in highly integrated optical circuits and sensing applications. PMID:27463720

  1. Vascular ring

    ... subclavian and left ligamentum ateriosus; Congenital heart defect - vascular ring; Birth defect heart - vascular ring ... Vascular ring is rare. It accounts for less than 1% of all congenital heart problems. The condition ...

  2. Reflective variable optical attenuators and fibre ring lasers for wavelength-division multiplexing systems

    Liu, He Liang

    Wavelength division multiplexing (WDM) optical fibre system is an important enabling technology to fulfill the demands for bandwidth in the modern information age. The main objective of this project is to study novel devices with the potential to enhance the performance of WDM systems. In particular, a novel reflective variable optical attenuator (RVOA) used for dynamic gain equalization (DGE) and fibre lasers based on an entirely new type of erbium-doped fibres with ultrawide tuning range were investigated theoretically and experimentally. We proposed a new type of RVOA device which could be potentially integrated with arrayed waveguide grating (AWG) to reduce the cost of DGE substantially. Initially, fibre-based RVOAs, fabricated with optical fibre components such as fibre coupler and Faraday rotator mirror, were investigated theoretically and experimentally. Larger attenuation range up to 22 dB was realized for fibre coupler-based ROVA with a Faraday rotator mirror and its polarization-dependent loss is about 0.5 dB. Then polymeric waveguide-based RVOAs were investigated theoretically and experimentally. Using an epoxy Novolak resin as core material and an UV-cured resin (Norland's NOA61) as cladding material, a polymeric waveguide RVOA was successfully fabricated. The dynamic 15 dB attenuation range was achieved and the PDL was less than 0.2 dB. The measured insertion loss of the polymeric waveguide RVOA was too large (about 18 dB) and was mainly induced by coupling loss, material loss and poor alignment. In the second part of the study, fibre ring lasers with continuous wavelength tuning over wide wavelength range and fibre ring lasers with discrete wavelength tuning were investigated. Tunable lasers are important devices in WDM systems because they could be employed as reserved sources and therefore avoiding the need to stock large inventory of lasers to cover the ITU-wavelength grid. In this project, erbium ions doped bismuth oxide glass fibres instead of

  3. Electromagnetic Calculation of Combined Earthing System with Ring Earth Electrode and Vertical Rods for Wind Turbine

    Fujii, Toshiaki; Yasuda, Yoh; Ueda, Toshiaki

    With the worldwide spread of wind turbine installations, various problems such as landscape issues, bird strikes and grid connections have arisen. Protection of wind turbines from lightning is cited as one of the main problems. Wind turbines are often struck by lightning because of their open-air locations, such as in mountainous areas, and their special configuration and very-high construction. Especially, low-voltage and control circuits can fail or suffer burnout while blades can incur serious damage if struck by lightning. Wind turbine failures caused by lightning strikes account for approximately 25% of all failures. The problem is regarded as a global one that needs immediate resolution. It is important to understand the impedance characteristics of wind turbine earthing systems from the viewpoint of lightning protection. A report from IEC TR61400-24 recommends a “ring earth electrode”. This was originally defined in IEC 61024 (currently revised and re-numbered as IEC 62305), where such an electrode is recommended to reduce touch and step voltages in households and buildings. IEC TR61400-24 also recommended additional electrodes of vertical or horizontal rods. However, these concepts have not been fully discussed from the viewpoint of its application to wind turbines. To confirm the effect of a combination of a ring earth electrode and additional vertical rods for protection of a wind turbine, this report uses the Finite Difference Time Domain (FDTD) method to present an electromagnetic transient analysis on such a wind turbine earthing system. The results show that an optimal combination can be arranged from viewpoints of lightning protection and construction cost. Thus, this report discusses how to establish a quantitative design methodology of the wind turbine earthing system to provide effective lightning protection.

  4. New energy ramping control system in the Pohang Light Source Storage Ring

    Kim, E S; Seo, J H; Nam, S H


    A new energy ramping control system is developed to increase electron beam energy from 2.0 GeV to 2.5 GeV in the Pohang Light Source storage ring. The control system shows faster energy ramping and more stable beam characteristics than the previous energy ramping control system that consists of an operator interface workstation, subsystem control computer and machine interface units. The previous system controls current settings of the magnet power supplies in multiple steps with different energy increment rate during the energy ramping. In order to improve synchronization of the magnet power supply systems and beam stabilities during the energy ramping, we developed the energy ramping controller hardware that is controlled using a network of optical fibers. Thus, the new ramping system is able to control more synchronously the magnet power supplies with a constant energy increment rate during the energy ramping. With this reliable synchronization, it is also possible to perform the energy de-ramping step fro...

  5. A System of Four Matrix Equations over von Neumann Regular Rings and Its Applications

    Qing Wen WANG


    We consider the system of four linear matrix equations A1X = C1, XB2 = C2, A3XB3 = C3 and A4XB4 = C4 over(R) , an arbitrary yon Neumann regular ring with identity. A necessary and sufficient condition for the existence and the expression of the general solution to the system are derived. As applications, necessary and sufficient conditions are given for the system of matrix equations A1X = C1 and A3X = C3 to have a bisymmetric solution, the system of matrix equations A1X = C1and A3XB3 = C3 to have a perselfconjugate solution over(R) with an involution and char ≠(R)2,respectively. The representations of such solutions are also presented. Moreover, some auxiliary results on other systems over(R)are obtained. The previous known results on some systems of matrix equations are special cases of the new results.

  6. Simulating the Librational Behaviour of Propeller Moons In The Saturnian Ring System

    Seiler, Michael; Seiss, Martin; Hoffmann, Holger; Spahn, Frank


    The propeller structure Blériot orbiting in the outer A ring of the Saturnian ring system has been one of the tremendous discoveries of the spacecraft Cassini [Tiscareno et al., 2010, ApJL]. The reconstruction of the orbital evolution of Blériot from recurrent observations in the ISS images yielded a systematic offset motion from the expected Keplerian orbit. This offset motion can be well described by three sinusoidal harmonics with amplitudes and periods of 1845, 152, 58 km and 11.1, 3.7 and 2.2 years, respectively [Sremčević et al., 2014, EPSC]. Oscillatory deviations from the Keplerian orbit are a known phenomenon for the Saturnian moons, which can be explained by resonant interactions with other moons [Spitale et al., 2006, AJ] and which look similar to the observation of Blériot.In this work we present our results from N-Body simulations, where we integrated the orbital evolution of a test particle, orbiting at the radial position of the propeller Blériot and 15 other moons of Saturn. Our simulation yield, that gravitational interactions with the larger moons result in reasonable and observable frequencies, but the resulting amplitudes of the librations are by far too small to explain the observations. Further mechanisms are needed, to amplify the amplitudes of the forced librations -- as e.g. by moonlet-ring interactions. Inspired by the recent work of Pan and Chiang [2010, ApJL; 2012, AJ] we introduce an alternative, physically more reasonable model. In our model, the moonlet is allowed to be slightly displaced with respect to its created gaps, resulting in a repulsive force. As a result, the moonlet's longitude starts to oscillate. In the presence of the additional external forcing by the outer moons the libration amplitude gets amplified, if the forcing frequency is close to the eigenfrequency of the system. Applying our model to Blériot, we can indeed reproduce a libration period of 13 years with an amplitude of about 2000 km.

  7. Hetarylazopyrazolone Dyes Based on Benzothiazole and Benzimidazole Ring Systems: Synthesis, Spectroscopic Investigation, and Computational Study

    Ebru Aktan


    Full Text Available In this study, the synthesized coupling component 1-(2-benzothiazolyl-3-methylpyrazol-5-one reacted with diazotised heterocyclic amines to afford six novel hetarylazopyrazolone dyes. These azo dyes based on benzothiazole and benzimidazole ring systems were characterized by spectral methods and elemental analyses. The solvatochromic behaviors of these dyes in various solvents were evaluated. The ground state geometries of the dyes were optimized using density functional theory (DFT. Solvent, acid-base, and substituent influences on the wavelength of the maximum absorption were examined in detail. Time-dependent density functional theory (TD-DFT calculations were performed to obtain the absorption spectra of the dyes in various solvents and the results compared with experimental values. Besides, frontier molecular orbitals (FMO analysis for the dyes is also described from the computational process.

  8. Research and Development on the Storage Ring Vacuum System for the APS Upgrade Project

    Stillwell, B.; Brajuskovic, B.; Carter, J.; Cease, H.; Lill, R.; Navrotski, G.; Noonan, J.; Suthar, K.; Walters, D.; Wiemerslage, G.; Zientek, J.; Sangroula, M.


    A number of research and development activities are underway at Argonne National Laboratory to build confidence in the designs for the storage ring vacuum system required for the Advanced Photon Source Up-grade project (APS-U) [1]. The predominant technical risks are: excessive residual gas pressures during operation; insufficient beam position monitor stability; excessive beam impedance; excessive heating by induced electrical surface currents; and insufficient operational reliability. Present efforts to mitigate these risks include: building and evaluating mockup assemblies; performing mechanical testing of chamber weld joints; developing computational tools; investigating design alternatives; and performing electrical bench measurements. Status of these activities and some of what has been learned to date will be shared.

  9. Photonic crystal channel drop filter based on ring-shaped defects for DWDM systems

    Dideban, Ali; Habibiyan, Hamidreza; Ghafoorifard, Hassan


    This paper presents a novel configuration of channel drop filters based on two-dimensional photonic crystal slabs in silicon-on-insulator platforms. The structure is composed of two photonic crystal line-defect waveguides as input and output ports, along with an L3 cavity with ring-shaped border holes. The effects of structural parameters and fabrication errors on resonance frequency and drop efficiency are investigated. Band structure and propagation of electromagnetic field through device are calculated by plane wave expansion and finite-difference time-domain methods. The results show that the quality factor and line-width of output signal are 5690 and 0.27 nm, respectively, indicating that the proposed filter can be properly used in dense wavelength division multiplexing systems with 0.8 nm channel spacing.

  10. Chaotic and Subharmonic Motion Analysis of Floating Ring Gas Bearing System by Hybrid Numerical Method

    Cheng-Chi Wang


    Full Text Available This paper studies the nonlinear dynamic behaviors including chaotic, subharmonic, and quasi-periodic motions of a rigid rotor supported by floating ring gas bearing (FRGB system. A hybrid numerical method combining the differential transformation method and the finite difference method used to calculate pressure distribution of FRGB system and rotor orbits. The results obtained for the orbits of the rotor center are in good agreement with those obtained using the traditional finite difference approach. Moreover, the hybrid method avoids the numerical instability problem suffered by the finite difference scheme at low values of the rotor mass and computational time-step. Moreover, power spectra, Poincaré maps, bifurcation diagrams and Lyapunov exponents are applied to examine the nonlinear dynamic response of the FRGB system over representative ranges of the rotor mass and bearing number, respectively. The results presented summarize the changes which take place in the dynamic behavior of the FRGB system as the rotor mass and bearing number are increased and therefore provide a useful guideline for the bearing system.

  11. Mechanisms of vegetation-ring formation in water-limited systems.

    Sheffer, Efrat; Yizhaq, Hezi; Shachak, Moshe; Meron, Ehud


    A common patch form in dryland landscapes is the vegetation ring. Vegetation patch formation has recently been attributed to self-organization processes that act to increase the availability of water to vegetation patches under conditions of water scarcity. The view of ring formation as a water-limited process, however, has remained largely unexplored. Using laboratory experiments and model studies we identify two distinct mechanisms of ring formation. The first mechanism pertains to conditions of high infiltration contrast between vegetated and bare soil, under which overland water flow is intercepted at the patch periphery. The decreasing amount of water that the patch core receives as the patch expands, leads to central dieback and ring formation. The second mechanism pertains to plants with large lateral root zones, and involves central dieback and ring formation due to increasing water uptake by the newly recruited individuals at the patch periphery. In general the two mechanisms act in concert, but the relative importance of each mechanism depends on environmental conditions. We found that strong seasonal rainfall variability favors ring formation by the overland-flow mechanism, while a uniform rainfall regime favors ring formation by the water-uptake mechanism. Our results explain the formation of rings by fast-growing species with confined root zones in a dry-Mediterranean climate, such as Poa bulbosa. They also explain the formation of rings by slowly growing species with highly extended root zones, such as Larrea tridentata (Creosotebush).

  12. Novel DC ring topology and protection system - a comprehensive solution for mega city power grids

    Haj-Maharsi, Mohamed Yassine


    The development of mega cities leads to increased load concentration and brings additional challenges to managing the electrical grid while keeping power available for critical loads. Techniques using FACTS devices are being applied to alleviate power management difficulties and to confine faults in their originating areas in order to limit the risk of cascading failures in the grid. The addition of many FACTS devices often results in control and protection coordination difficulties, power oscillations between connected networks, subsynchronous resonance problems, and torsional interactions with nearby generator units. The most effective solution is obtained when the individual AC subsystems representing sources and loads are decoupled so a fault in a given subsystem is not propagated to another subsystem. This solution can be achieved by the deployment of a DC system where power sources and loads are connected to the DC bus through voltage source converters. For a mega city, this would be conceived as a DC ring feeding multiple loads and connected to remote and local power sources. Unfortunately, the lack of fast DC circuit breakers has been one of the key issues affecting extensive applications of DC systems with common DC buses; a DC fault would discharge all the capacitors of the DC bus and cause delays in system recovery and possibly a wide system collapse. In this research, I provide a comprehensive solution to mega city power grid problems by proposing a DC system topology that enables grid expansions without affecting existing protection settings or changing existing AC breaker ratings. I also propose the means for protecting the DC system by designing a fast DC breaker and developing a control algorithm capable of isolating DC faults without blocking converter stations or depleting DC bus capacitors. My contribution is three folds: (1) I modeled and simulated Shanghai power grid and performed a study to identify short circuit and voltage stability problems

  13. MRI-compatible ultrasound heating system with ring-shaped phased arrays for breast tumor thermal therapy.

    Chen, Hung-Nien; Chen, Guan-Ming; Lin, Bo-Sian; Lien, Pi-Hsien; Chen, Yung-Yaw; Chen, Gin-Shin; Lin, Win-Li


    Therapeutic ultrasound transducers can carry out precise and efficient power deposition for tumor thermal therapy under the guidance of magnetic resonance imaging. For a better heating, organ-specific ultrasound transducers with precision location control system should be developed for tumors located at various organs. It is feasible to perform a better heating for breast tumor thermal therapy with a ring-shaped ultrasound phased-array transducer. In this study, we developed ring-shaped phased-array ultrasound transducers with 1.0 and 2.5 MHz and a precision location control system to drive the transducers to the desired location to sonicate the designated region. Both thermo-sensitive hydrogel phantom and ex vivo fresh pork were used to evaluate the heating performance of the transducers. The results showed that the ring-shaped phased array ultrasound transducers were very promising for breast tumor heating with the variation of heating patterns and without overheating the ribs.

  14. Ring blowers. Ring blower

    Nakahara, Y.; Okamura, T.; Takahashi, M. (Fuji Electric Co. Ltd., Tokyo (Japan))


    Features, structures and several products of ring blowers were outlined. The ring blower is featured by its medium characteristics because it is higher in air pressure than a turboblower and larger in airflow than a vane blower, and it is applicable flexibly to not only air blasting but various industrial fields such as suction transfer. As several products corresponding to various fields, the followings were outlined: the low noise type with optimum shapes of inlet, outlet and casing cover for reducing noises by 10 dB or more, the heat resistant, water-tight and explosion-proof types suitable for severe environmental conditions, the multi-voltage type for every country served at different voltages, the high air pressure type with two pressure rise stages, and the large airflow type with a wide impeller. In addition, as special use products, the glass fiber reinforced unsatulated polyester ring blower for respiration apparatus, and the variable speed blushless DC motor-driven one for medical beds were outlined. 2 refs., 9 figs., 1 tab.

  15. Saturn's largest ring.

    Verbiscer, Anne J; Skrutskie, Michael F; Hamilton, Douglas P


    Most planetary rings in the Solar System lie within a few radii of their host body, because at these distances gravitational accelerations inhibit satellite formation. The best known exceptions are Jupiter's gossamer rings and Saturn's E ring, broad sheets of dust that extend outward until they fade from view at five to ten planetary radii. Source satellites continuously supply the dust, which is subsequently lost in collisions or by radial transport. Here we report that Saturn has an enormous ring associated with its outer moon Phoebe, extending from at least 128R(S) to 207R(S) (Saturn's radius R(S) is 60,330 km). The ring's vertical thickness of 40R(S) matches the range of vertical motion of Phoebe along its orbit. Dynamical considerations argue that these ring particles span the Saturnian system from the main rings to the edges of interplanetary space. The ring's normal optical depth of approximately 2 x 10(-8) is comparable to that of Jupiter's faintest gossamer ring, although its particle number density is several hundred times smaller. Repeated impacts on Phoebe, from both interplanetary and circumplanetary particle populations, probably keep the ring populated with material. Ring particles smaller than centimetres in size slowly migrate inward and many of them ultimately strike the dark leading face of Iapetus.

  16. Charge transfer in Li/CFx-silver vanadium oxide hybrid cathode batteries revealed by solid state 7Li and 19F nuclear magnetic resonance spectroscopy

    Sideris, Paul J.; Yew, Rowena; Nieves, Ian; Chen, Kaimin; Jain, Gaurav; Schmidt, Craig L.; Greenbaum, Steve G.


    Solid state 7Li and 19F magic angle spinning nuclear magnetic resonance (MAS NMR) experiments are conducted on several cathodes containing CFx-Silver vanadium oxide (CFx-Ag2V4O11) hybrid cathodes discharged to 50% depth of discharge (DoD) and stored at their open-circuit voltage for a period of one and three months. Three carbonaceous sources for the CFx phase are investigated: petroleum coke-based, fibrous, and mixed fibrous. For each hybrid cathode, a measurable increase in the relative amount of lithium fluoride is observed after a three month resting period in both the 7Li and 19F NMR spectra. These changes are attributed to lithium ion migration from the silver vanadium oxide to the CFx phase during the resting period, and help clarify the mechanism behind high power handling capability of this cathode.

  17. Experimental investigation of the 19F( n, α)16N reaction excitation function in the neutron energy range of 4 to 7.35 MeV

    Bondarenko, I. P.; Khryachkov, V. A.; Ivanova, T. A.; Kuz'minov, B. D.; Semenova, N. N.; Sergachev, A. I.


    The interaction of neutrons with light nuclei study is of interest for understanding nuclear-reaction mechanisms. Fluorine nuclei are worth particular attention because they are abundant in the core of the promising molten-salt reactors and can noticeably affect the chain reaction kinetics. In this work we have experimentally investigated the 19F( n, α)16N reaction cross-section at neutron energies ranging from 4 to 7.35 MeV.

  18. 19F magnetic resonance imaging of perfluorocarbons for the evaluation of response to antibiotic therapy in a Staphylococcus aureus infection model.

    Tobias Hertlein

    Full Text Available BACKGROUND: The emergence of antibiotic resistant bacteria in recent decades has highlighted the importance of developing new drugs to treat infections. However, in addition to the design of new drugs, the development of accurate preclinical testing methods is essential. In vivo imaging technologies such as bioluminescence imaging (BLI or magnetic resonance imaging (MRI are promising approaches. In a previous study, we showed the effectiveness of (19F MRI using perfluorocarbon (PFC emulsions for detecting the site of Staphylococcus aureus infection. In the present follow-up study, we investigated the use of this method for in vivo visualization of the effects of antibiotic therapy. METHODS/PRINCIPAL FINDINGS: Mice were infected with S. aureus Xen29 and treated with 0.9% NaCl solution, vancomycin or linezolid. Mock treatment led to the highest bioluminescence values during infection followed by vancomycin treatment. Counting the number of colony-forming units (cfu at 7 days post-infection (p.i. showed the highest bacterial burden for the mock group and the lowest for the linezolid group. Administration of PFCs at day 2 p.i. led to the accumulation of (19F at the rim of the abscess in all mice (in the shape of a hollow sphere, and antibiotic treatment decreased the (19F signal intensity and volume. Linezolid showed the strongest effect. The BLI, cfu, and MRI results were comparable. CONCLUSIONS: (19F-MRI with PFCs is an effective non-invasive method for assessing the effects of antibiotic therapy in vivo. This method does not depend on pathogen specific markers and can therefore be used to estimate the efficacy of antibacterial therapy against a broad range of clinically relevant pathogens, and to localize sites of infection.

  19. Determination of magnitudes and relative signs of 1H-19F coupling constants through 1D- and 2D-TOCSY experiments.

    Espinosa, Juan F


    A novel methodology based on 1D- and 2D-TOCSY experiments is described for a quick and accurate measurement of proton-fluorine coupling constants in fluorinated organic compounds. The magnitude of the (1)H-(19)F coupling was measured from the displacement between the relayed peaks associated with the α or β spin state of the fluorine, and its relative sign was derived from the sense of the displacement.

  20. Self-Assembly of Peptide Amphiphiles Designed as Imaging Probes for 19F and Relaxation-Enhanced 1H imaging

    Preslar, Adam Truett

    This work incorporates whole-body imaging functionality into peptide amphiphile (PA) nanostructures used for regenerative medicine to facilitate magnetic resonance imaging (MRI). Two strategies were employed: 1. Conjugation of gadolinium chelates to peptide nanostructures to monitor biomaterial degradation in vivo with MRI and inductively-coupled plasma-mass spectroscopy (ICP-MS) 2. Synthesis of perfluorinated moiety-bearing peptide amphiphiles for 19F-MRI. The Gd(III) chelate gadoteridol was conjugated by copper-catalyzed "click" chemistry to a series of PAs known to form cylindrical nanostructures. By fitting nuclear magnetic resonance dispersion (NMRD) profiles to the Solomon-Bloembergen-Morgan (SBM) equations, it was observed that the water exchange parameter (tauM) depended on thermal annealing or calcium ion cross-linking. The sequence C16V 3A3E3G(Gd) exhibited an acceleration of nearly 100 ns after thermal annealing and calcium addition. These gadolinium-labeled PAs were used to track in vivo degradation of gels within the tibialis anterior muscle in a murine model. The half-life of biomaterial degradation was determined to be 13.5 days by inductively coupled plasma mass spectrometry (ICP-MS) of Gd(III). Gel implants could be monitored by MRI for eight days before the signal dispersed due to implant degradation and dilution. Additionally, nanostructures incorporating highly fluorinated domains were investigated for use as MRI contrast agents. Short, perfluoroalkyane tails of seven or eight carbon atoms in length were grafted to PA sequences containing a V2A2 beta-sheet forming sequence. The V2A2 sequence is known to drive 1D nanostructure assembly. It was found that the sequences C7F13V2A 2E2 and C7F13V2A 2K3 formed 1D assemblies in water which transition from ribbon-like to cylindrical shape as pH increases from 4.5 to 8.0. Ribbon-like nanostructures had reduced magnetic resonance signal by T 2 relaxation quenching, whereas their cylindrical counterparts

  1. Modules over group rings of groups with restrictions on the system of all proper subgroups

    Olga Dashkova


    Full Text Available We consider the class M of R{modules where R is an associative ring. Let A be a module over a group ring RG, G be a group and let L(G be the set of all proper subgroups of G. We suppose that if H 2 L(G then A=CA(H belongs to M. We study an RG{module A such that G 6= G0, CG(A = 1. We consider the cases: 1 M is the class of all artinian R{modules, R is either the ring of integers or the ring of p{adic integers; 2 M is the class of all nite R{modules, R is an associative ring; 3 M is the class of all nite R{modules, R= F is a nite eld.

  2. Synthesis and antiproliferative activity of the ring system [1,2]oxazolo[4,5-g]indole.

    Barraja, Paola; Caracausi, Libero; Diana, Patrizia; Spanò, Virginia; Montalbano, Alessandra; Carbone, Anna; Parrino, Barbara; Cirrincione, Girolamo


    Brand new ring: A series of 27 derivatives of the new ring system [1,2]oxazolo[4,5-g]indole were conveniently prepared and tested at the NCI for antiproliferative studies. Several of them showed good inhibitory activity toward all tested cell lines, reaching GI50 values generally at the micromolar and sub-micromolar levels and in some cases at nanomolar concentrations. The mean GI50 values, calculated on the full panel, were in the range 0.25-7.08 μM.

  3. The direct link model for polymer rings using topological field theory and the second topological moment in dense systems

    Otto, Matthias [Institut fuer Theoretische Physik, Universitaet Goettingen, Goettingen (Germany)


    Polymer rings in solution are either permanently entangled or are not. Permanent topological restrictions give rise to additional entropic interactions apart from the ones arising due to mere chain flexibility or excluded volume. Conversely, entangled polymer rings systems may be formed by closing randomly entangled flexible linear chains. The dependence of linking numbers between randomly entangled rings on the chain length, more specifically the second topological moment , i.e. the average squared linking number, may be determined. In this paper, an approach recently discussed in mathematical physics and called Abelian BF theory, is presented which allows one to express the linking constraint in its simplest form, the Gauss integral, in terms of two gauge fields. The model of Brereton and Shah for a single ring entangled with many other surrounding rings is rederived. The latter model is finally used to calculate the second topological moment, in agreement with a recent result by Ferrari, Kleinert, and Lazzizzera obtained using n-component {phi}{sup 4} theory for the limit n{yields}0. (author)

  4. Synthesis of the furo[2,3-b]chromene ring system of hyperaspindols A and B

    Danielle L. Paterson


    Full Text Available The synthesis of the unique furo[2,3-b]chromene ring system found in hyperaspidinols A and B, acylphloroglucinols from Hypericum chinense has been achieved in twelve steps. By comparison of the NMR spectra of the synthesized compounds with those of the natural products, a relative stereochemistry is suggested, especially that of the ketal carbon.

  5. Thermodynamic black di-rings

    Iguchi, Hideo


    Previously the five dimensional $S^1$-rotating black rings have been superposed in concentric way by some solitonic methods and regular systems of two $S^1$-rotating black rings were constructed by the authors and then Evslin and Krishnan (we called these solutions black di-rings). In this place we show some characteristics of the solutions of five dimensional black di-rings, especially in thermodynamic equilibrium. After the summary of the di-ring expressions and their physical quantities, first we comment on the equivalence of the two different solution-sets of the black di-rings. Then the existence of thermodynamic black di-rings are shown, in which both iso-thermality and iso-rotation between the inner black ring and the outer black ring are realized. We also give detailed analysis of peculiar properties of the thermodynamic black di-ring including discussion about a certain kind of thermodynamic stability (instability) of the system.

  6. Circumbinary ring, circumstellar disks, and accretion in the binary system UY Aurigae

    Tang, Ya-Wen; Ho, Paul T. P. [Academia Sinica, Institute of Astronomy and Astrophysics, Taipei, Taiwan (China); Dutrey, Anne; Guilloteau, Stéphane; Di Folco, Emmanuel [Université de Bordeaux, Observatoire Aquitain des Sciences de l' Univers, CNRS, UMR 5804, Laboratoire d' Astrophysique de Bordeaux, 2 rue de l' Observatoire, BP 89, F-33271 Floirac Cedex (France); Piétu, Vincent; Gueth, Fréderic [IRAM, 300 rue de la piscine, F-38406 Saint Martin d' Hères Cedex (France); Beck, Tracy [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Boehler, Yann [Centro de Radioastronomìa y Astrofìsica, UNAM, Apartado Postal 3-72, 58089 Morelia, Michoacàn (Mexico); Bary, Jeff [Department of Physics and Astronomy, Colgate University, 13 Oak Drive, Hamilton, NY 13346 (United States); Simon, Michal, E-mail: [Stony Brook University, Stony Brook, NY 11794-3800 (United States)


    Recent exo-planetary surveys reveal that planets can orbit and survive around binary stars. This suggests that some fraction of young binary systems which possess massive circumbinary (CB) disks may be in the midst of planet formation. However, there are very few CB disks detected. We revisit one of the known CB disks, the UY Aurigae system, and probe {sup 13}CO 2-1, C{sup 18}O 2-1, SO 5(6)-4(5) and {sup 12}CO 3-2 line emission and the thermal dust continuum. Our new results confirm the existence of the CB disk. In addition, the circumstellar (CS) disks are clearly resolved in dust continuum at 1.4 mm. The spectral indices between the wavelengths of 0.85 mm and 6 cm are found to be surprisingly low, being 1.6 for both CS disks. The deprojected separation of the binary is 1.''26 based on our 1.4 mm continuum data. This is 0.''07 (10 AU) larger than in earlier studies. Combining the fact of the variation of UY Aur B in R band, we propose that the CS disk of an undetected companion UY Aur Bb obscures UY Aur Ba. A very complex kinematical pattern inside the CB disk is observed due to a mixing of Keplerian rotation of the CB disk, the infall and outflow gas. The streaming gas accreting from the CB ring toward the CS disks and possible outflows are also identified and resolved. The SO emission is found to be at the bases of the streaming shocks. Our results suggest that the UY Aur system is undergoing an active accretion phase from the CB disk to the CS disks. The UY Aur B might also be a binary system, making the UY Aur a triple system.

  7. Novel Zinc-Catalytic Systems for Ring-Opening Polymerization of ε-Caprolactone

    Karolina Żółtowska


    Full Text Available Polycaprolactone (PCL is a biodegradable synthetic polymer that is currently widely used in many pharmaceutical and medical applications. In this paper we describe the coordination ring-opening polymerization of ε-caprolactone in the presence of two newly synthesized catalytic systems: diethylzinc/gallic acid and diethylzinc/propyl gallate. The chemical structures of the obtained PCLs were characterized by 1H- or 13C-NMR, FTIR spectroscopy and MALDI TOF mass spectrometry. The average molecular weight of the resulting polyesters was analysed by gel permeation chromatography and a viscosity method. The effects of temperature, reaction time and type of catalytic system on the polymerization process were examined. Linear PCLs with defined average molecular weight were successfully obtained. Importantly, in some cases the presence of macrocyclic products was not observed during the polymerization process. This study provides an effective method for the synthesis of biodegradable polyesters for medical and pharmaceutical applications due to the fact that gallic acid/propyl gallate are commonly used in the pharmaceutical industry.

  8. A new virtual ring-based system matrix generator for iterative image reconstruction in high resolution small volume PET systems.

    Li, K; Safavi-Naeini, M; Franklin, D R; Han, Z; Rosenfeld, A B; Hutton, B; Lerch, M L F


    A common approach to improving the spatial resolution of small animal PET scanners is to reduce the size of scintillation crystals and/or employ high resolution pixellated semiconductor detectors. The large number of detector elements results in the system matrix--an essential part of statistical iterative reconstruction algorithms--becoming impractically large. In this paper, we propose a methodology for system matrix modelling which utilises a virtual single-layer detector ring to greatly reduce the size of the system matrix without sacrificing precision. Two methods for populating the system matrix are compared; the first utilises a geometrically-derived system matrix based on Siddon's ray tracer method with the addition of an accurate detector response function, while the second uses Monte Carlo simulation to populate the system matrix. The effectiveness of both variations of the proposed technique is demonstrated via simulations of PETiPIX, an ultra high spatial resolution small animal PET scanner featuring high-resolution DoI capabilities, which has previously been simulated and characterised using classical image reconstruction methods. Compression factors of 5 x 10(7) and 2.5 x 10(7)are achieved using this methodology for the system matrices produced using the geometric and Monte Carlo-based approaches, respectively, requiring a total of 0.5-1.2 GB of memory-resident storage. Images reconstructed from Monte Carlo simulations of various point source and phantom models, produced using system matrices generated via both geometric and simulation methods, are used to evaluate the quality of the resulting system matrix in terms of achievable spatial resolution and the CRC, CoV and CW-SSIM index image quality metrics. The Monte Carlo-based system matrix is shown to provide the best image quality at the cost of substantial one-off computational effort and a lower (but still practical) compression factor. Finally, a straightforward extension of the virtual ring

  9. Detection of the non-steroidal anti-inflammatory drug niflumic acid in humans: a combined 19F-MRS in vivo and in vitro study.

    Bilecen, Deniz; Schulte, Anja-Carina; Kaspar, Armin; Küstermann, Eckerhardt; Seelig, Joachim; Elverfeldt, Dominik; Scheffler, Klaus


    This study describes for the first time results of a (19)F-MRS study on humans exposed to the fluorinated non-steroidal anti-inflammatory drug niflumic acid. The accumulation and elimination of this commercially available selective prostaglandin synthase inhibitor is studied after an oral bolus in the human liver, in blood plasma and in urine samples. The in vivo spectra of the liver display two resonances with a similar increase in signal intensity during the investigation period of 240 min. One resonance refers to the parent compound niflumic acid (P), whereas the second resonance corresponds to a metabolite (M1) formed by the biotransformation by liver enzymes. The spectroscopic comparison with model compounds suggests 4'-hydroxyniflumic acid as the metabolite. During the entire experiment the concentration ratios of these resonances (P/M1) ranged between 0.7 and 0.9, indicating a high metabolite concentration most probably due to an efficient first pass metabolism. Both resonances (P, M1) were observed in the in vitro study of the blood plasma samples after plasma protein denaturation. However, in comparison to the liver spectra, the amount of the metabolite M1 is very small with a P/M1-ratio of 36.6 after 90 min and 16.1 after the end of measurement. This finding suggests an efficient biliary excretion of the metabolite M1, which bypasses the blood circulation system. Both resonances are also identified in the native urine samples. The signal intensity of the parent compound dominates the spectra of all urine samples, whereas the signal intensity of M1 increases slowly reaching a similar value to the parent compound P at the end of the measurement. This observation demonstrates an effective renal elimination of niflumic acid and suggests the existence of an enterohepatic circuit with a re-entry mechanism for the biliary excreted metabolite M1. In the urine spectra, an additional metabolite M2 is found. This resonance exhibits a low but constant signal

  10. Dusty plasma (Yukawa) rings

    Sheridan, T E


    One-dimensional and quasi-one-dimensional strongly-coupled dusty plasma rings have been created experimentally. Longitudinal (acoustic) and transverse (optical) dispersion relations for the 1-ring were measured and found to be in very good agreement with the theory for an unbounded straight chain of particles interacting through a Yukawa (i.e., screened Coulomb or Debye-H\\"uckel) potential. These rings provide a new system in which to study one-dimensional and quasi-one-dimensional physics.

  11. Token ring technology report


    Please note this is a Short Discount publication. This report provides an overview of the IBM Token-Ring technology and products built by IBM and compatible vendors. It consists of two sections: 1. A summary of the design trade-offs for the IBM Token-Ring. 2. A summary of the products of the major token-ring compatible vendors broken down by adapters and components, wiring systems, testing, and new chip technology.

  12. Application of ring tectonic theory to Mercury and other solar system bodies

    Mckinnon, W. B.


    It is pointed out that multiringed structures, by their presence or absence, provide a powerful tool for deciphering the thermal histories of the solid planets. The theory of ring tectonics considered by Melosh and McKinnon (1978) and Melosh et al. (1980) establishes the framework of that undertaking. The present investigation has the objective to apply this conceptualization in detail to the multiringed basins on Mercury, taking into account also a brief review concerning the current state of understanding of ring tectonics on the moon, Mars, earth, Ganymede, and Callisto. The small, icy satellites of Saturn are also discussed. The mechanics of multiple ring formation are related to the collapse of the transient basin cavity when the excavation depth and lithosphere thickness are comparable. Attention is given to the Caloris Basin on Mercury, the peak ring basins on Mercury, and the Argyre Basin on Mars.

  13. Application of ring tectonic theory to Mercury and other solar system bodies

    Mckinnon, W. B.


    It is pointed out that multiringed structures, by their presence or absence, provide a powerful tool for deciphering the thermal histories of the solid planets. The theory of ring tectonics considered by Melosh and McKinnon (1978) and Melosh et al. (1980) establishes the framework of that undertaking. The present investigation has the objective to apply this conceptualization in detail to the multiringed basins on Mercury, taking into account also a brief review concerning the current state of understanding of ring tectonics on the moon, Mars, earth, Ganymede, and Callisto. The small, icy satellites of Saturn are also discussed. The mechanics of multiple ring formation are related to the collapse of the transient basin cavity when the excavation depth and lithosphere thickness are comparable. Attention is given to the Caloris Basin on Mercury, the peak ring basins on Mercury, and the Argyre Basin on Mars.

  14. Vortex rings

    Akhmetov, D.G. [Lavrentiev Institute of Hydrodynamics, Novosibirsk (Russian Federation)


    This book presents a comprehensive coverage of the wide field of vortex rings. The book presents the results of systematic experimental investigations, theoretical foundation, as well as the practical applications of vortex rings, such as the extinction of fires at gushing gas and oil wells. All the basic properties of vortex rings as well as their hydrodynamic structures are presented. Special attention is paid to the formation and motion of turbulent vortex rings. (orig.)

  15. Intravaginal rings as delivery systems for microbicides and multipurpose prevention technologies

    Thurman AR


    Full Text Available Andrea Ries Thurman, Meredith R Clark, Jennifer Hurlburt, Gustavo F Doncel CONRAD, Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, VA, USA Abstract: There is a renewed interest in delivering pharmaceutical products via intravaginal rings (IVRs. IVRs are flexible torus-shaped drug delivery systems that can be easily inserted and removed by the woman and that provide both sustained and controlled drug release, lasting for several weeks to several months. In terms of women's health care products, it has been established that IVRs effectively deliver contraceptive steroids and steroids for the treatment of postmenopausal vaginal atrophy. A novel application for IVRs is the delivery of antiretroviral drugs for the prevention of human immunodeficiency virus (HIV genital infection. Microbicides are antiviral drugs delivered topically for HIV prevention. Recent reviews of microbicide IVRs have focused on technologies in development and optimizing ring design. IVRs have several advantages, including the ability to deliver sustained drug doses for long periods of time while bypassing first pass metabolism in the gut. IVRs are discreet, woman-controlled, and do not require a trained provider for placement or fitting. Previous data support that women and their male sexual partners find IVRs highly acceptable. Multipurpose prevention technology (MPT products provide protection against unintended/mistimed pregnancy and reproductive tract infections, including HIV. Several MPT IVRs are currently in development. Early clinical testing of new microbicide and MPT IVRs will require a focus on safety, pharmacokinetics and pharmacodynamics. Specifically, IVRs will have to deliver tissue concentrations of drugs that are pharmacodynamically active, do not cause mucosal alterations or inflammation, and do not change the resident microbiota. The emergence of resistance to antiretrovirals will need to be investigated. IVRs should not

  16. New Psychoactive Substances: Chemistry, Pharmacology, Metabolism, and Detectability of Amphetamine Derivatives With Modified Ring Systems.

    Welter-Luedeke, Jessica; Maurer, Hans H


    In recent years, new amphetamine derivatives with modified ring systems were sold and consumed as new drugs of abuse. They belong together with other new drugs of abuse classes to the so-called new psychoactive substances (NPS). The chemistry, pharmacology, toxicology, metabolism, and toxicokinetics are shortly discussed of camfetamine, 3 methylphenyl-amphetamines (2-MA, 3-MA, and 4-MA), 2-methiopropamine (2-MPA), and 5-(2-aminopropyl)benzofuran (5-APB), 6-(2-aminopropyl)benzofuran (6-APB, so-called "benzofury") and their N-methyl derivatives 5-MAPB and 6-MAPB. Only a rough assessment of the pharmacology and toxicology NPS can be performed in most cases using published data of analogs, trip reports, and described clinical cases. Accordingly, they all act more or less as central nervous stimulants mainly by increasing the concentration of the neurotransmitters noradrenaline, dopamine, and serotonin (5-HT) by inducing their release and reuptake inhibition. Thus, the acute toxicity is associated with the sympathomimetic effects, such as mydriasis, hyperthermia, hypertension, tachycardia, insomnia, and anxiety. With the exception of 5- and 6-APB, these NPS were extensively metabolized by N-demethylation and/or aromatic hydroxylation catalyzed by various cytochrome P450 isoenzymes followed by partial glucuronidation and/or sulfation. For urinalysis, the unchanged drugs and/or the nor-metabolites are the main targets.

  17. Understanding the Dynamical Evolution of the Earth Radiation Belt and Ring Current Coupled System

    Shprits, Yuri; Usanova, Maria; Kellerman, Adam; Drozdov, Alexander


    Modeling and understanding the ring current and radiation belt-coupled system has been a grand challenge since the beginning of the space age. In this study we show long-term simulations with a 3D Versatile Electron Radiation Belt (VERB) code of modeling the radiation belts with boundary conditions derived from observations around geosynchronous orbit. Simulations can reproduce long term variations of the electron radiation belt fluxes and show the importance of local acceleration, radial diffusion, loss to the atmosphere and loss to the magnetopause. We also present 4D VERB simulations that include convective transport, radial diffusion, pitch angle scattering and local acceleration. VERB simulations show that the lower energy inward transport is dominated by the convection and higher energy transport is dominated by the diffusive radial transport. We also show that at energies of 100s of keV, a number of processes work simultaneously, including convective transport, radial diffusion, local acceleration, loss to the loss cone and loss to the magnetopause. The results of the simulation of the March 2013 storm are compared with Van Allen Probes observations.

  18. Biosynthetic studies on the tropane ring system of the tropane alkaloids from Datura stramonium.

    Duran-Patron, R; O'Hagan, D; Hamilton, J T; Wong, C W


    Isotopic labelling experiments have been carried out in Datura stramonium root cultures with the following isotopically labelled precursors; [2H3]- [2-13C, 2H3]-, [1-13C, 18O2]-acetates, 2H2O, [2H3-methyl]-methionine, [2-13C]-phenyllactate, [3-2H]-tropine and [2'-13C, 3-2H]-littorine. The study explored the incorporation of isotope into the tropane ring system of littorine 1 and hyoscyamine 2 and revealed that deuterium from acetate is incorporated only into C-6 and C-7, and not into C-2 and C-4 as previously reported. Oxygen-18 was not retained at a detectable level into the C(3)-O bond from [1-13C, 18O2]-acetate. The intramolecular nature of the rearrangement of littorine 1 to hyoscyamine 2 is revealed again by a labelling study using [2'-13C, 3-2H]-littorine, [2-13C]-phenyllactate and [3-2H]-tropine.

  19. Ring theory

    Rowen, Louis H


    This is an abridged edition of the author's previous two-volume work, Ring Theory, which concentrates on essential material for a general ring theory course while ommitting much of the material intended for ring theory specialists. It has been praised by reviewers:**""As a textbook for graduate students, Ring Theory joins the best....The experts will find several attractive and pleasant features in Ring Theory. The most noteworthy is the inclusion, usually in supplements and appendices, of many useful constructions which are hard to locate outside of the original sources....The audience of non

  20. On the Centro-symmetric Solution of a System of Matrix Equations over a Regular Ring with Identity

    Qingwen Wang; Haixia Chang; Chunyan Lin


    In this paper, we find the centro-symmetric solution of a system of matrix equations over an arbitrary regular ring R with identity. We first derive some necessary and sufficient conditions for the existence and an explicit expression of the general solution of the system of matrix equations A1X1 = C1, A2X1 = C2, A3X2 = C3, A4X2 = C4 and A5X1B5 + A6X2B6= C5 over R. By using the above results, we establish two criteria for the existence and the representation of the general centro-symmetric solution of the system of matrix equations AaX = Ca, AbX = Cb and AcXBc = Cc over the ring R.

  1. Conformational Plasticity of the Cell-Penetrating Peptide SAP As Revealed by Solid-State (19)F-NMR and Circular Dichroism Spectroscopies.

    Afonin, Sergii; Kubyshkin, Vladimir; Mykhailiuk, Pavel K; Komarov, Igor V; Ulrich, Anne S


    The cell-penetrating peptide SAP, which was designed as an amphipathic poly-l-proline helix II (PPII), was suggested to self-assemble into regular fibrils that are relevant for its internalization. Herein we have analyzed the structure of SAP in the membrane-bound state by solid-state (19)F-NMR, which revealed other structural states, in addition to the expected surface-aligned PPII. Trifluoromethyl-bicyclopentyl-glycine (CF3-Bpg) and two rigid isomers of trifluoromethyl-4,5-methanoprolines (CF3-MePro) were used as labels for (19)F-NMR analysis. The equilibria between different conformations of SAP were studied and were found to be shifted by the substituents at Pro-11. Synchrotron-CD results suggested that substituting Pro-11 by CF3-MePro governed the coil-to-PPII equilibrium in solution and in the presence of a lipid bilayer. Using CD and (19)F-NMR, we examined the slow kinetics of the association of SAP with membranes and the dependence of the SAP conformational dynamics on the lipid composition. The peptide did not bind to lipids in the solid ordered phase and aggregated only in the liquid ordered "raft"-like bilayers. Self-association could not be detected in solution or in the presence of liquid disordered membranes. Surface-bound amphipathic SAP in a nonaggregated state was structured as a mixture of nonideal extended conformations reflecting the equilibrium already present in solution, i.e., before binding to the membrane.

  2. Kondo Resonance versus Fano Interference in Double Quantum Dots Coupled to a Two-Lead One-Ring System

    CHEN Xiong-Wen; SHI Zhen-Gang; CHEN Bao-Ju; SONG Ke-Hui


    We analyse the transport properties of a coupled double quantum dot (DQD) device with one of the dots (QD1) coupled to metallic leads and the other (QD2) embedded in an Aharonov-Bhom (A-B) ring by means of the slave-boson mean-Geld theory. It is found that in this system, the Kondo resonance and the Fano interference exist simultaneously, the enhancing Kondo effect and the increasing hopping of the QD2-Ring destroy the localized electron state in the QD2 for the QD1-leads, and accordingly, the Fano interference between the DQD-leads and the QD1-leads are suppressed. Under some conditions, the Fano interference can be quenched fully and the single Kondo resonance of the QD1-leads comes into being. Moreover, when the magnetic flux of the A-B ring is zero, the influence of the parity of the A-B ring on the transport properties is very weak, but this inSuence becomes more obvious with non-zero magnetic flux. Thus this model may be a candidate for future device applications.

  3. Annual Report FY2013-- A Kinematically Complete, Interdisciplinary, and Co-Institutional Measurement of the 19F(α,n) Cross-section for Nuclear Safeguards Science

    Peters, William A [ORNL; Smith, Michael Scott [ORNL; Clement, Ryan [INL; Tan, Wanpeng [University of Notre Dame; Stech, Ed [University of Notre Dame; Cizewski, J A [Rutgers University; Febbraro, Michael [University of Michigan; Madurga Flores, Miguel [ORNL


    The goal of this proposal is to enable neutron detection for precision Non-Destructive Assays (NDAs) of actinide-fluoride samples. Neutrons are continuously generated from a UFx matrix in a container or sample as a result of the interaction of alpha particles from uranium-decay α particles with fluorine nuclei in the matrix. Neutrons from 19F(α,n)22Na were once considered a poorly characterized background for assays of UFx samples via 238U spontaneous fission neutron detection [SMI2010B]. However, the yield of decay-α-driven neutrons is critical for 234,235U LEU and HEU assays, as it can used to determine both the total amount of uranium and the enrichment [BER2010]. This approach can be extremely valuable in a variety of safeguard applications, such as cylinder monitoring in underground uranium storage facilities, nuclear criticality safety studies, nuclear materials accounting, and other nonproliferation applications. The success of neutron-based assays critically depends on an accurate knowledge of the cross section of the (α,n) reaction that generates the neutrons. The 40% uncertainty in the 19F(α,n)22Na cross section currently limits the precision of such assays, and has been identified as a key factor in preventing accurate enrichment determinations [CRO2003]. The need for higher quality cross section data for (α,n) reactions has been a recurring conclusion in reviews of the nuclear data needs to support safeguards. The overarching goal of this project is to enable neutron detection to be used for precision Non- Destructive Assays (NDAs) of actinide-fluoride samples. This will significantly advance safeguards verification at existing declared facilities, nuclear materials accounting, process control, nuclear criticality safety monitoring, and a variety of other nonproliferation applications. To reach this goal, Idaho National Laboratory (INL), in partnership with Oak Ridge National Laboratory (ORNL), Rutgers University (RU), and the University of Notre

  4. NMR shielding and spin–rotation constants of {sup 175}LuX (X = {sup 19}F, {sup 35}Cl, {sup 79}Br, {sup 127}I) molecules

    Demissie, Taye B. [Centre for Theoretical and Computational Chemistry Department of Chemistry, UiT – The Arctic University of Norway, N-9037 Tromsø (Norway)


    This presentation demonstrates the relativistic effects on the spin-rotation constants, absolute nuclear magnetic resonance (NMR) shielding constants and shielding spans of {sup 175}LuX (X = {sup 19}F, {sup 35}Cl, {sup 79}Br, {sup 127}I) molecules. The results are obtained from calculations performed using density functional theory (non-relativistic and four-component relativistic) and coupled-cluster calculations. The spin-rotation constants are compared with available experimental values. In most of the molecules studied, relativistic effects make an order of magnitude difference on the NMR absolute shielding constants.

  5. Refractive index sensing using a multimode interference-based fiber sensor in a cavity ring-down system

    Silva, Susana; Frazão, Orlando


    This work presents a multimode interference-based fiber sensor in a cavity ring-down system for sensing temperature-induced refractive index (RI) changes of water. The sensing head is based in multimodal interference (MMI) and it was placed inside the fiber loop cavity of the CRD system. A modulated laser source was used to send pulses down into the fiber loop cavity and an erbium-doped fiber amplifier (EDFA) was placed in the fiber ring to provide an observable signal with a reasonable decay time. The behavior of the sensing head to temperature was studied due to its intrinsic sensitivity to said parameter - a sensitivity of -1.6×10-9 μs/°C was attained. This allowed eliminating the temperature component from RI measurement of water and a linear sensitivity of 580 μs/RIU in the RI range of 1.324-1.331 was obtained.

  6. One-pot three-component synthesis of quinoxaline and phenazine ring systems using Fischer carbene complexes

    Priyabrata Roy


    Full Text Available One-pot three-component coupling of o-alkynylheteroaryl carbonyl derivatives with Fischer carbene complexes and dienophiles leading to the synthesis of quinoxaline and phenazine ring systems has been investigated. This involves the generation of furo[3,4-b]pyrazine and furo[3,4-b]quinoxaline as transient intermediates, which were trapped with Diels–Alder dienophiles. This is the first report on furo[3,4-b]pyrazine intermediates.

  7. Formation of diverse ring-satellite systems around Centaurs through tidal disruption at close encounters with giant planet

    Hyodo, Ryuki; Genda, Hidenori; Ohtsuki, Keiji


    Centaurs are minor planets orbiting between Jupiter and Neptune that have or had crossing orbits with one or more giant planets. Recent observations and reinterpretation of previous observations have revealed the existence of ring systems around 10199 Chariklo and 2060 Chiron. However, the origin of the ring systems around such a minor planet is still an open question. Here, we propose that the tidal disruption of a differentiated object that experiences a close encounter with a giant planet could naturally form diverse ring-satellite systems around the Centaurs. During the close encounter, the icy mantle of the passing object is preferentially ripped off by the planet's tidal force and the debris is distributed mostly within the Roche limit of the largest remnant body. Assuming the existence of $20-50$wt% silicate core below the icy mantle, a disk of particles is formed when the objects pass within $0.4-0.8$ of the planet's Roche limit with the relative velocity at infinity $3-6$km s$^{-1}$ and 8h initial sp...

  8. Visualization of abscess formation in a murine thigh infection model of Staphylococcus aureus by 19F-magnetic resonance imaging (MRI.

    Tobias Hertlein

    Full Text Available BACKGROUND: During the last years, (19F-MRI and perfluorocarbon nanoemulsion (PFC emerged as a powerful contrast agent based MRI methodology to track cells and to visualize inflammation. We applied this new modality to visualize deep tissue abscesses during acute and chronic phase of inflammation caused by Staphylococcus aureus infection. METHODOLOGY AND PRINCIPAL FINDINGS: In this study, a murine thigh infection model was used to induce abscess formation and PFC or CLIO (cross linked ironoxides was administered during acute or chronic phase of inflammation. 24 h after inoculation, the contrast agent accumulation was imaged at the site of infection by MRI. Measurements revealed a strong accumulation of PFC at the abscess rim at acute and chronic phase of infection. The pattern was similar to CLIO accumulation at chronic phase and formed a hollow sphere around the edema area. Histology revealed strong influx of neutrophils at the site of infection and to a smaller extend macrophages during acute phase and strong influx of macrophages at chronic phase of inflammation. CONCLUSION AND SIGNIFICANCE: We introduce (19F-MRI in combination with PFC nanoemulsions as a new platform to visualize abscess formation in a murine thigh infection model of S. aureus. The possibility to track immune cells in vivo by this modality offers new opportunities to investigate host immune response, the efficacy of antibacterial therapies and the influence of virulence factors for pathogenesis.

  9. Free variable selection QSPR study to predict (19)F chemical shifts of some fluorinated organic compounds using Random Forest and RBF-PLS methods.

    Goudarzi, Nasser


    In this work, two new and powerful chemometrics methods are applied for the modeling and prediction of the (19)F chemical shift values of some fluorinated organic compounds. The radial basis function-partial least square (RBF-PLS) and random forest (RF) are employed to construct the models to predict the (19)F chemical shifts. In this study, we didn't used from any variable selection method and RF method can be used as variable selection and modeling technique. Effects of the important parameters affecting the ability of the RF prediction power such as the number of trees (nt) and the number of randomly selected variables to split each node (m) were investigated. The root-mean-square errors of prediction (RMSEP) for the training set and the prediction set for the RBF-PLS and RF models were 44.70, 23.86, 29.77, and 23.69, respectively. Also, the correlation coefficients of the prediction set for the RBF-PLS and RF models were 0.8684 and 0.9313, respectively. The results obtained reveal that the RF model can be used as a powerful chemometrics tool for the quantitative structure-property relationship (QSPR) studies.

  10. Analysis of the System of Wavy and Ring Deformation in Draping

    李兴刚; 朱耀庭


    The paper analyzes the principle of positioning of waves by notching at the bottom of the waves in garment draping from the dynamic perspective, and search for the best molding effect under 45° to fabric grain as the model baseline. Wavy and ring deformation laws are proved by the sample photographs.

  11. Step towards optimizing friction, wear and oil control in piston ring/cylinder systems

    Krause, H.H.


    In a reciprocating-piston engine, cylinder liner temperature has the greatest influence on friction and lubricating film thickness. With rising liner temperature, hydrodynamic friction forces and thus friction losses decrease. At the same time, the lubricating film thicknesses on the rings drop and the mixed friction forces at TDC and BDC rise. Wear increases. With increasing speed and constant liner temperature, hydrodynamic friction and thus friction losses increase. Lubricating films become thicker, mixed friction decreases and so does wear. Under increasing pressure loads at the same liner temperature, lubricating film thicknesses decrease, especially during the expansion stroke. Mixed friction increases and so does wear. Among the various running surface profiles examined for the first compression ring, there is one optimal profile as regards friction, wear and oil control: the results confirm that the profile used on modern rings in standard production today is already optimal for today's engines, having been developed purposefully over the years. The correlations found between friction and lubricating film thickness, between mixed friction forces and ring and liner wear rates, and between lubricating thickness and oil consumption show that it is possible to determine accurately the physical correlations involved by using such a test rig, and that the results can also be applied to a fired production engine. (orig.).

  12. Single bunch injection system for storage ring FEL using an rf photoinjector

    O'Shea, P. G.; Lancaster, J. A.; Madey, J. M. J.; Sachtschale, R.; Jones, R.


    RF photoinjectors have gained acceptance as the source of choice for high-brightness electron accelerators, but have been quite expensive to build and difficult to operate. In this paper we describe the successful operation of an inexpensive, simple and reliable rf photoinjector suitable for single bunch injection into storage rings. For optimum storage ring FEL and Compton Backscatter performance, we require that the electrons be injected to specified ring rf buckets and no others. The injector-linac electron gun is a single-cell s-band rf gun with a LaB6 cathode. The gun is followed by an a-magnet momentum filter and buncher. The LaB6 cathode can be operated in a pure thermionic mode, a laser switched photoemission mode, or in a combined mode. The laser is a near-UV TEA nitrogen laser with a 600 ps pulse, and 0-50 Hz repetition rate. We routinely inject 0.1 nC bunches at 270 MeV. The ratio of charge in the primary ring bucket to that in the other buckets is better than 1000.

  13. Site-specific protein backbone and side-chain NMR chemical shift and relaxation analysis of human vinexin SH3 domain using a genetically encoded {sup 15}N/{sup 19}F-labeled unnatural amino acid

    Shi, Pan [National Laboratory for Physical Science at Microscale, University of Science and Technology of China, Hefei, Anhui 230026 (China); School of Life Science, University of Science and Technology of China, Hefei, Anhui 230026 (China); Xi, Zhaoyong; Wang, Hu [School of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026 (China); Shi, Chaowei [National Laboratory for Physical Science at Microscale, University of Science and Technology of China, Hefei, Anhui 230026 (China); School of Life Science, University of Science and Technology of China, Hefei, Anhui 230026 (China); Xiong, Ying, E-mail: [School of Life Science, University of Science and Technology of China, Hefei, Anhui 230026 (China); Tian, Changlin, E-mail: [National Laboratory for Physical Science at Microscale, University of Science and Technology of China, Hefei, Anhui 230026 (China)


    Research highlights: {yields} Chemical synthesis of {sup 15}N/{sup 19}F-trifluomethyl phenylalanine. {yields} Site-specific incorporation of {sup 15}N/{sup 19}F-trifluomethyl phenylalanine to SH3. {yields} Site-specific backbone and side chain chemical shift and relaxation analysis. {yields} Different internal motions at different sites of SH3 domain upon ligand binding. -- Abstract: SH3 is a ubiquitous domain mediating protein-protein interactions. Recent solution NMR structural studies have shown that a proline-rich peptide is capable of binding to the human vinexin SH3 domain. Here, an orthogonal amber tRNA/tRNA synthetase pair for {sup 15}N/{sup 19}F-trifluoromethyl-phenylalanine ({sup 15}N/{sup 19}F-tfmF) has been applied to achieve site-specific labeling of SH3 at three different sites. One-dimensional solution NMR spectra of backbone amide ({sup 15}N){sup 1}H and side-chain {sup 19}F were obtained for SH3 with three different site-specific labels. Site-specific backbone amide ({sup 15}N){sup 1}H and side-chain {sup 19}F chemical shift and relaxation analysis of SH3 in the absence or presence of a peptide ligand demonstrated different internal motions upon ligand binding at the three different sites. This site-specific NMR analysis might be very useful for studying large-sized proteins or protein complexes.

  14. Comparative study of the results of compound tibial shaft fractures treated by Ilizarov ring fixators and limb reconstruction system fixators

    Chandra Prakash Pal; Harish Kumar; Deepak Kumar; K.S.Dinkar; Vivek Mittal; Naveen Kumar Singh


    Purpose: Ilizarov ring fixator and limb reconstruction system (LRS) fixators have been used in the management of complex tibial fractures with severe soft tissue injuries, compound tibial fractures, and infected tibial nonunion for which conventional internal fixation cannot be contemplated.Fracture union and distraction osteogenesis can be done simultaneously with these external fixators, allowing early weight bearing.Several previous studies have shown almost equal results of rail and ring fixators for the compound tibial shaft fractures.Thus we performed a prospective study to evaluate the union rate, functional outcome and amount of limb lengthening after the treatment of compound tibial shaft fractures with or without infected nonunion by ring or LRS fixators.Methods: This prospective study was done at Sarojini Naidu Medical College and Hospital, Agra, India and included 32 patients of compound tibial shaft fractures with or without infected nonunion.There were 26 males and 6 females and the average age was 40 years.Patients were randomly divided into two groups (n =16 for each): one underwent Ilizarov fixation and the other received LRS fixation.Cases were followed up for 3-24 months, 6 months on average from September 2012 to October 2014.Functional and radiological outcomes were assessed using the Association for the Study and Application of Methods of Ilizarov (ASAMI) criteria for both rail and ring fixators.Results: Union was achieved in all cases.Radiological outcome was found excellent in 68.75%, good in 18.75% and fair in 12.50% of cases treated by rail fixators whereas it was excellent in 56.25%, good in 18.75%, fair in 12.50% and poor in 12.50% of cases treated by ring fixators.Functional result was satisfactory in 75.00% of cases treated by rail fixator and 68.75% of cases treated by ring fixators whereas the corresponding rate of unsatisfactory was 25.00% vs.31.25%.Conclusion: In our short-term assessment, LRS fixators show a

  15. Synthesis and action on the central nervous system of mescaline analogues containing piperazine or homopiperazine rings.

    Majchrzak, M W; Kotełko, A; Guryn, R; Lambert, J B; Szadowska, A; Kowalczyk, K


    Structural juxtaposition of the 3,4,5-trimethoxyphenyl group in the same molecule with a piperazine or homopiperazine ring has been realized in a series of mescaline analogues (I-IV) as part of an investigation into the pharmacological properties of the seven-membered perhydro-1,4-diazepines (homopiperazines). The analogous six-membered piperazines were synthesized and tested as reference substances to determine whether the seven-membered ring conveyed special properties. A variety of pharmacological tests of action on the CNS showed that replacement of the amino group in mescaline by the heterocycles significantly alters the biological activity. In particular, both the piperazine and the homopiperazine derivatives displayed sedative activity to about the same extent.

  16. Progress on the Design of the Storage Ring Vacuum System for the Advanced Photon Source Upgrade Project

    Stillwell, B.; Billett, B.; Brajuskovic, B.; Carter, J.; Kirkus, E.; Lale, M.; Lerch, J.; Noonan, J.; O' Neill, M.; Rocke, B.; Suthar, K.; Walters, D.; Wiemerslage, G.; Zientek, J.


    Recent work on the design of the storage ring vacuum system for the Advanced Photon Source Upgrade project (APS-U) includes: revising the vacuum system design to accommodate a new lattice with reverse bend magnets, modifying the designs of vacuum chambers in the FODO sections for more intense incident synchrotron radiation power, modifying the design of rf-shielding bellows liners for better performance and reliability, modifying photon absorber designs to make better use of available space, and integrated planning of components needed in the injection, extraction and rf cavity straight sections. An overview of progress in these areas is presented.

  17. Earth: A Ringed Planet?

    Hancock, L. O.; Povenmire, H.


    Among the most beautiful findings of the Space Age have been the discoveries of planetary rings. Not only Saturn but also Jupiter, Uranus and Neptune have rings; Saturn’s ring system has structures newly discovered; even Saturn's moon Rhea itself has a ring. All these are apparently supplied by material from the planetary moons (Rhea's ring by Rhea itself). The question naturally arises, why should the Earth not have a ring, and on the other hand, if it does, why has it not been observed? No rings have yet been observed in the inner solar system, but after all, rings in the inner solar system might simply tend to be fainter and more transient than those of the outer solar system: the inner solar system is more affected by the solar wind, and the Sun’s perturbing gravitational influence is greater. J.A. O’Keefe first suggested (1980) that Earth might have a ring system of its own. An Earth ring could account for some climate events. O’Keefe remarked that formation or thickening of a ring system in Earth’s equatorial plane could drive glaciation by deepening the chill of the winter hemisphere. (It is very well established that volcanic dust is an effective agent for the extinction of sunlight; this factor can be overwhelmingly apparent in eclipse observations.) O’Keefe died in 2000 and the speculation was not pursued, but the idea of an Earth ring has a prima facie reasonableness that calls for its renewed consideration. The program of this note is to hypothesize that, as O’Keefe proposed: (a) an Earth ring system exists; (b) it affects Earth's weather and climate; (c) the tektite strewn fields comprise filaments of the ring fallen to Earth's surface on various occasions of disturbance by comets or asteroids. On this basis, and drawing on the world's weather records, together with the Twentieth Century Reanalysis by NCEP/CIRES covering the period 1870-2010 and the geology of the tektite strewn fields, we herein propose the hypothesized Earth ring

  18. Stereocontrolled Additions to a Rigid Bicyclo [3.3.0] Octane Ring System


    terpenoid class of compounds called dolabellanes will be addressed. Dolabellanes diterpenoids have been isolated from both marine and terrestrial...eleven-membered ring structure; the second is the presence of various stereocenters. Four terpenoids are highlighted in Figure 1. The first two...Degeneracy: having the same energy. Deprotonate: to remove a hydrogen from a compound. Diterpenoid: a terpenoid formed from four isoprene units; each

  19. Regulation of Split Linear Systems Over Rings: Coefficient-Assignment and Observers,


    IEEE Transactions on Automatic Control , Vol. AC-27, No. 1, February 1982 0018-9286/82/0200-0104$00.75 Q 1982 IEEE SECURITY C4 A%,( A11...strictly proper transfer matrix over the ring X If lion of splitnes is not very restrictive, we express Z as IEEE TRANSACTIONS ON AUTOMATIC CONTROL , VOL...i + P2 + p 108 IEEE TRANSACTIONS ON AUTOMATIC CONTROL , VOL. AC-27, NO. I, FEBRUARY 1982 Then there es sts a p x p polynomial matrix

  20. (13)C and (19)F solid-state NMR and X-ray crystallographic study of halogen-bonded frameworks featuring nitrogen-containing heterocycles.

    Szell, Patrick M J; Gabriel, Shaina A; Gill, Russell D D; Wan, Shirley Y H; Gabidullin, Bulat; Bryce, David L


    Halogen bonding is a noncovalent interaction between the electrophilic region of a halogen (σ-hole) and an electron donor. We report a crystallographic and structural analysis of halogen-bonded compounds by applying a combined X-ray diffraction (XRD) and solid-state nuclear magnetic resonance (SSNMR) approach. Single-crystal XRD was first used to characterize the halogen-bonded cocrystals formed between two fluorinated halogen-bond donors (1,4-diiodotetrafluorobenzene and 1,3,5-trifluoro-2,4,6-triiodobenzene) and several nitrogen-containing heterocycles (acridine, 1,10-phenanthroline, 2,3,5,6-tetramethylpyrazine, and hexamethylenetetramine). New structures are reported for the following three cocrystals, all in the P21/c space group: acridine-1,3,5-trifluoro-2,4,6-triiodobenzene (1/1), C6F3I3·C13H9N, 1,10-phenanthroline-1,3,5-trifluoro-2,4,6-triiodobenzene (1/1), C6F3I3·C12H8N2, and 2,3,5,6-tetramethylpyrazine-1,3,5-trifluoro-2,4,6-triiodobenzene (1/1), C6F3I3·C8H12N2. (13)C and (19)F solid-state magic-angle spinning (MAS) NMR is shown to be a convenient method to characterize the structural features of the halogen-bond donor and acceptor, with chemical shifts attributable to cocrystal formation observed in the spectra of both nuclides. Cross polarization (CP) from (19)F to (13)C results in improved spectral sensitivity in characterizing the perfluorinated halogen-bond donor when compared to conventional (1)H CP. Gauge-including projector-augmented wave density functional theory (GIPAW DFT) calculations of magnetic shielding constants, along with optimization of the XRD structures, provide a final set of structures in best agreement with the experimental (13)C and (19)F chemical shifts. Data for carbons bonded to iodine remain outliers due to well-known relativistic effects.

  1. Transcending Voyager: A Deeper Look at Neptune's Ring-Moon System

    Showalter, Mark


    We will use the High Resolution Channel {HRC} of ACS to study the inner rings, arcs and moons of Neptune with a sensitivity that exceeds that achieved by Voyager 2 during its 1989 flyby. Our study will reveal any moons down to V magnitude 25.5, to address a peculiar truncation in the size distribution of inner moons and to look for the "shepherds" and source bodies for Neptune's dusty rings. {For comparison, Neptune's smallest known moon is Naiad, at magnitude 23.9}. Recent ground-based studies show that the mysterious arcs in the Adams Ring continue to shift and change, and may be fading away entirely. We will obtain the visual-band data uniquely necessary to determine whether the arcs are fading. Long-term monitoring of the arcs at high resolution and sensitivity will reveal their gradual changes more clearly and enable us to assess the role of Galatea, whose resonances are widely believed to confine the arcs.

  2. Macroscopic anatomy of the ringed seal [Pusa (Phoca) hispida] lower respiratory system.

    Smodlaka, H; Henry, R W; Reed, R B


    This investigation serves to document the normal anatomical features of the lower respiratory tract of the ringed seal [Pusa (phoca) hispida]. Evaluation of embalmed specimens and tracheobronchial casts showed that the right lung of this seal consists of four lobes while the left has only three lobes. The ventral margins of the lungs do not reach the sternum causing them to form the boundary of the broad recessus costomediastinalis. Lung lobation corresponds with bronchial tree division. Pulmonary venous drainage includes right and left common veins draining ipsilateral cranial and middle lung lobes, and one common caudal vein draining both caudal lobes and the accessory lobe. The right and left pulmonary arteries divide into cranial and caudal branches at the level of the principal bronchus. The ringed seal has three tracheobronchial lymph nodes. The trachea has an average of 87 cartilages that exhibit a pattern of random anastomoses between adjacent rings. The trachea exhibits to a small degree the dorsoventrally flattened pattern that is described in other pinnipeds. The tracheal diameter is smaller than that of the canine.

  3. Synthesis of the new ring system bispyrido[4',3':4,5]pyrrolo [1,2-a:1',2'-d]pyrazine and its deaza analogue.

    Parrino, Barbara; Spanò, Virginia; Carbone, Anna; Barraja, Paola; Diana, Patrizia; Cirrincione, Girolamo; Montalbano, Alessandra


    Derivatives of the new ring systems bispyrido[4',3':4,5]pyrrolo[1,2-a:1',2'-d] pyrazine-6,13-dione and its deaza analogue pyrido[4'',3'':4',5']pyrrolo-[1',2':4,5]pyrazino [1,2-a]indole-6,13-dione were conveniently synthesized through a four-step sequence. Symmetrical derivatives of the former ring system were obtained through self condensation. On the other hand, condensation of 6-azaindole carboxylic acid with indole 2-carboxylic acid afforded the deaza analogue ring system. Derivatives of the title ring system were tested by the National Cancer Institute (Bethesda, MD, USA) and four of them exhibited modest activity against MCF7 (a breast cancer cell line) and/or UO-31 (a renal cancer cell line).

  4. Synthesis of the New Ring System Bispyrido[4',3':4,5]pyrrolo [1,2-a:1',2'-d]pyrazine and Its Deaza Analogue

    Barbara Parrino


    Full Text Available Derivatives of the new ring systems bispyrido[4',3':4,5]pyrrolo[1,2-a:1',2'-d] pyrazine-6,13-dione and its deaza analogue pyrido[4'',3'':4',5']pyrrolo-[1',2':4,5]pyrazino [1,2-a]indole-6,13-dione were conveniently synthesized through a four-step sequence. Symmetrical derivatives of the former ring system were obtained through self condensation. On the other hand, condensation of 6-azaindole carboxylic acid with indole 2-carboxylic acid afforded the deaza analogue ring system. Derivatives of the title ring system were tested by the National Cancer Institute (Bethesda, MD, USA and four of them exhibited modest activity against MCF7 (a breast cancer cell line and/or UO-31 (a renal cancer cell line.

  5. Stopping power measurements for {sup 16}O, {sup 19}F and {sup 28}Si ions in Mylar by a transmission technique

    Chekirine, M., E-mail: [Departement de physique, Faculte des sciences, Universite Saad Dahleb, B.P. 270, route de Soumaa, Blida (Algeria); Ammi, H., E-mail: [Centre de Recherche Nucleaire d' Alger, 2, Bd. Frantz Fanon, B.P. 399, Alger-Gare (Algeria); Choudhury, R.K.; Biswas, D.C. [Bhabha Atomic Research Centre, Nuclear Physics Division, Mumbai (India); Tobbeche, S., E-mail: [Faculte des sciences, Universite El-Hadj Lakhdar, Batna 05000 (Algeria)


    Electronic energy loss of charged particles in materials is a fundamental process responsible for the unique response of materials in applications of advanced nuclear power, radiation detectors and advanced processing of electronic devices. In this study, stopping powers of {sup 16}O, {sup 19}F and {sup 28}Si heavy ions crossing thin Mylar foils have been determined in transmission geometry. The energy loss was measured over a continuous range of energies from 1.6 to 5.5 MeV/n (MeV per nucleon) using the data that was tagged by a surface barrier detector (SBD) with and without stopping foils. We have compared the obtained stopping values to those predicted by SRIM-2008 computer code, ICRU-73 stopping data tables and MSTAR calculations. The effective charge values of these heavy ions have been also deduced from the experimental set of data.


    Rajesh G


    Full Text Available Supra mitral ring is a rare cause for congenital mitral valve obstr uction. The reported incidence of supramitral ring is 0.2-0.4% in general population and 8% in patients with congenital mitral valve disease. The condition is characterized by an abnormal ridge of connective tissue often circumferential in shape ,on the atrial side of the mitral valve encroaching on the orifice of the mitral valve. It may adhere to the leaflets of the valve and restrict their movements. Although a supramitral ring may be rarely nonobstructive, it often results in mitral valve inflow obstruction.

  7. Development of Low Level RF Control Systems for Superconducting Heavy Ion Linear Accelerators, Electron Synchrotrons and Storage Rings

    Aminov, Bachtior; Kolesov, Sergej; Pekeler, Michael; Piel, Christian; Piel, Helmut


    Since 2001 ACCEL Instruments is supplying low level RF control systems together with turn key cavity systems. The early LLRF systems used the well established technology based on discrete analogue amplitude and phase detectors and modulators. Today analogue LLRF systems can make use of advanced vector demodulators and modulators combined with a fast computer controlled analogue feed back loop. Feed forward control is implemented to operate the RF cavity in an open loop mode or to compensate for predictable perturbations. The paper will introduce the general design philosophy and show how it can be adapted to different tasks as controlling a synchrotron booster nc RF system at 500 MHz, or superconducting storage ring RF cavities, as well as a linear accelerator at 176 MHz formed by a chain of individually driven and controlled superconducting λ/2 cavities.

  8. Design and System Integration of the Superconducting Wiggler Magnets for the Compact Linear Collider Damping Rings

    Schoerling, D; Bernhard, A; Bragin, A; Karppinen, M; Maccaferri, R; Mezentsev, N; Papaphilippou, Y; Peiffer, P; Rossmanith, R; Rumolo, G; Russenschuck, S; Vobly, P; Zolotarev, K


    To achieve high luminosity at the collision point of the Compact Linear Collider (CLIC) the normalized horizontal and vertical emittances of the electron and positron beams must be reduced to 500 nm and 4 nm before the beams enter the 1.5TeV linear accelerators. An effective way to accomplish ultra-low emittances with only small effects on the electron polarization is using damping rings operating at 2.86 GeV equipped with superconducting wiggler magnets. This paper describes a technical design concept for the CLIC damping wigglers.

  9. Routes to complex dynamics in a ring of unidirectionally coupled systems.

    Perlikowski, P; Yanchuk, S; Wolfrum, M; Stefanski, A; Mosiolek, P; Kapitaniak, T


    We study the dynamics of a ring of unidirectionally coupled autonomous Duffing oscillators. Starting from a situation where the individual oscillator without coupling has only trivial equilibrium dynamics, the coupling induces complicated transitions to periodic, quasiperiodic, chaotic, and hyperchaotic behavior. We study these transitions in detail for small and large numbers of oscillators. Particular attention is paid to the role of unstable periodic solutions for the appearance of chaotic rotating waves, spatiotemporal structures, and the Eckhaus effect for a large number of oscillators. Our analytical and numerical results are confirmed by a simple experiment based on the electronic implementation of coupled Duffing oscillators.

  10. Aharonov-Bohm Oscillations and Fano Resonance of a Coupled Dot-Ring System

    XIONG Yong-Jian


    @@ We derive an exact expression for the transmission coefficient through an Aharonov-Bohm ring with a side-coupled quantum dot using the scattering-matrix approach. We show a sudden AB phase change by π as the quantum dot is tuned across the resonance. The Aharonov-Bohm oscillation amplitude can be modulated effectively by tuning the quantum dot level. The transmission coefficient has an expression of the generalized Fano form with a complex Fano parameter q in the presence of the Aharonov-Bohm flux.

  11. Liquid ring vacuum pumps, compressors and systems conventional and hermetic design

    Bannwarth, Helmut


    Based on the very successful German editions, this English version has been thoroughly updated and revised to reflect the developments of the last years and the latest innovations in the field.Throughout, the author makes excellent use of real-life examples and highly praised didactics to disseminate his expert knowledge needed by vacuum technology users and engineers in their daily work at industrial plants, as consultants or in design offices. He covers in detail the most modern liquid ring pumps, with chapters dedicated to maintenance, explosion prevention and general procedures for saf

  12. Transition between different quantum states in a mesoscopic system: The superconducting ring

    Horane, E.M. [Instituto Balseiro, Universidad Nacional de Cuyo and Comision Nacional de Energia Atomica, 8400 Bariloche (Argentina); Castro, J.I. [Departamento Fisico-Quimica, Facultad Filosofia Humanidades y Artes, Universidad Nacional de San Juan, San Juan (Argentina); Buscaglia, G.C.; Lopez, A. [Instituto Balseiro, and Centro Atomico Bariloche, Universidad Nacional de Cuyo and Comision Nacional de Energia Atomica, 8400 Bariloche (Argentina)


    We investigate the thermodynamic properties of a superconducting ring, both analytically and numerically, relying upon the Ginzburg-Landau theory. We find that modulated solutions for the order parameter play a role in describing the thermodynamic transitions between consecutive modes of uniform order parameter, associated with different quantum numbers. Exact expressions for these solutions are given in terms of elliptic functions. We identify the family of energy extrema which, being saddle points of the energy in the functional space of the distributions of the order parameter, represent the energy barrier to be overcome for transitions between different solutions. {copyright} {ital 1996 The American Physical Society.}

  13. Donor impurity states and related optical response in a lateral coupled dot-ring system under applied electric field

    Correa, J.D. [Departamento de Ciencias Básicas, Universidad de Medellín, Medellín (Colombia); Mora-Ramos, M.E. [Centro de Investigación en Ciencias, Instituto de Ciencias Básicas y Aplicadas, Universidad Autonoma del Estado de Morelos, Av. Universidad 1001, CP 62209 Cuernavaca, Morelos (Mexico); Duque, C.A., E-mail: [Grupo de Materia Condensada-UdeA, Instituto de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín (Colombia)


    A study on the effects of an externally applied electric field on the linear optical absorption and relative refractive index change associated with transitions between off-center donor impurity states in laterally coupled quantum dot-ring system is reported. Electron states are calculated within the effective mass and parabolic band approximations by means of an exact diagonalization procedure. The states and the optical response in each case show significant sensitivity to the geometrical distribution of confining energies as well as to the strength of the applied field.

  14. Cave Rings


    hypothesis, that cave rings are formed in the same manner as coffee rings[3], that is, due to the enhanced deposition at the edges of sessile drops ...ring’ is the deposit formed when a sessile drop of a solution containing dissolved particles, such as coffee or salt, dries. This was investigated by...who expanded on Deegan et al.[3] to find an exact form for the evaporation flux over a sessile drop . It turns out that solving 179 for the flux is

  15. Development of a Turn-by-Turn Beam Position Monitoring System for Multiple Bunch Operation of the ATF Damping Ring

    Burrows, P N; Kraljevic, N Blaskovic; Christian, G B; Davis, M R; Perry, C; Apsimon, R J; Constance, B; Gerbershagen, A; Resta-Lopez, J


    An FPGA-based monitoring system has been developed to study multi-bunch beam instabilities in the damping ring (DR) of the KEK Accelerator Test Facility (ATF). The system utilises a stripline beam position monitor (BPM) and single-stage down-mixing BPM processor. The system is designed to record the horizontal and/or vertical positions of up to three bunches in the DR with c. 150ns bunch spacing, or the head bunch of up to three trains in a multi-bunch mode with a bunch spacing of 5.6 ns. The FPGA firmware and data acquisition software allow the recording of turnby-turn data. An overview of the system and performance results will be presented.

  16. The Enceladus Ring


    [figure removed for brevity, see original site] The Enceladus Ring (labeled) This excellent view of the faint E ring -- a ring feature now known to be created by Enceladus -- also shows two of Saturn's small moons that orbit within the ring, among a field of stars in the background. The E ring extends from three to eight Saturn radii -- about 180,000 kilometers (118,000 miles) to 482,000 kilometers (300,000 miles). Its full extent is not visible in this view. Calypso (22 kilometers, or 14 miles across) and Helene (32 kilometers, or 20 miles across) orbit within the E ring's expanse. Helene skirts the outer parts of the E ring, but here it is projected in front of a region deeper within the ring. Calypso and Helene are trojan satellites, or moons that orbit 60 degrees in front or behind a larger moon. Calypso is a Tethys trojan and Helene is a trojan of Dione. An interesting feature of note in this image is the double-banded appearance of the E-ring, which is created because the ring is somewhat fainter in the ringplane than it is 500-1,000 kilometers (300-600 miles) above and below the ringplane. This appearance implies that the particles in this part of the ring have nonzero inclinations (a similar affect is seen in Jupiter's gossamer ring). An object with a nonzero inclination does not orbit exactly at Saturn's ringplane. Instead, its orbit takes it above and below the ringplane. Scientists are not entirely sure why the particles should have such inclinations, but they are fairly certain that the reason involves Enceladus. One possible explanation is that all the E ring particles come from the plume of icy material that is shooting due south out of the moon's pole. This means all of the particles are created with a certain velocity out of the ringplane, and then they orbit above and below that plane. Another possible explanation is that Enceladus produces particles with a range of speeds, but the moon gravitationally scatters any particles that lie very close to

  17. Stealing and Leakage Monitoring System for Sensitive File in RingO Layer%Ring0层敏感文件窃泄密监测系统

    王晓箴; 严坚; 吴焕; 刘宝旭


    为使敏感文件免遭窃泄密攻击的威胁,设计并实现一个基于Ring0层的主机型敏感文件窃泄密监测系统,通过敏感文件查找、文件异常行为监测等功能,对敏感文件进行实时监测和保护.该系统已应用于实际工作中,取得了良好效果.%To keep the sensitive file away from the thread of stealing and leakage, this paper designs and implements a stealing and leakage monitor system based on Ring0 privileged code. The system can monitor and protect confidential files promptly by using the components of file searching and unordinary action monitoring. The system's performance is satisfying in practice.

  18. A season in Saturn's rings: Cycling, recycling and ring history

    Esposito, L. W.; Meinke, B. K.; Albers, N.; Sremcevic, M.


    Cassini experiments have watched Saturn's ring system evolve before our eyes. Images and occultations show changes and transient events. The rings are a dynamic and complex geophysical system, incompletely modeled as a single-phase fluid. Key Cassini observations: High resolution images show straw, propellers, embedded moonlets, and F ring objects. Multiple UVIS, RSS and VIMS occutlations indicate multimodal ringlet and edge structure, including free and forced modes along with stochastic perturbations that are most likely caused by nearby mass concentrations. Vertical excursions are evident at ring edges and in other perturbed regions. The rings are occasionally hit by meteorites that leave a signature that may last centuries; meteoritic dust pollutes the rings. Temperature, reflectance and transmission spectra are influenced by the dynamical state of the ring particles. Saturn's Equinox 2009: Oblique lighting exposed vertical structure and embedded objects. The rings were the coldest ever. Images inspired new occultation and spectral analysis that show abundant structure in the perturbed regions. The rings are more variable and complex than we had expected prior to this seasonal viewing geometry. Sub-kilometer structure in power spectral analysis: Wavelet analysis shows features in the strongest density waves and at the shepherded outer edge of the B ring. Edges are variable as shown by multiple occultations and occultations of double stars. F ring kittens: 25 features seen in the first 102 occultations show a weak correlation with Prometheus location. We interpret these features as temporary aggregations. Simulation results indicate that accretion must be enhanced to match the kittens' size distribution. Images show that Prometheus triggers the formation of transient objects. Propellers and ghosts: Occulations and images provide evidence for small moonlets in the A, B and C rings. These indicate accretion occurs inside the classical Roche limit. Implications

  19. Ring Enlargement of Three-Membered Boron Heterocycles upon Reaction with Organic π Systems: Implications for the Trapping of Borylenes.

    Krasowska, Małgorzata; Bettinger, Holger F


    New low-energy pathways for the reaction between substituted boriranes and borirenes with unsaturated hydrocarbons (ethyne or ethene) were discovered using density functional and coupled cluster theory. The interaction between the π bond of the hydrocarbon and the empty p orbital of the boron center leads to ring expansion of the three-membered to a five-membered boron heterocycle. The reactions are strongly exothermic and have low or even no barriers. They involve intermediates with a pentacoordinate boron center with two hydrocarbon molecules coordinating to boron akin to metal-olefin complexes. These borylene complexes are shallow minima on the potential energy surfaces. But significantly higher barriers for ring formation are computed for 1,5-cyclooctadiene and dibenzocyclooctatetraene complexes of borylenes, making these complexes likely detectable under appropriate experimental conditions. Our computational findings have implications for the interpretation of trapping experiments of thermally generated small borylenes with excess of small π systems. Because of very low barriers for reactions of three-membered boron heterocycles with π systems and the at least locally large excess of the latter under such conditions, formation of five-membered boron heterocycles should be considered.

  20. Multimode interference-based fiber sensor in a cavity ring-down system for refractive index measurement

    Silva, Susana; Frazão, Orlando


    This work reports a multimode interference-based fiber sensor in a cavity ring-down system (CRD) for sensing temperature-induced refractive index (RI) changes of water. The sensing head is based in multimodal interference (MMI) and it is placed inside the fiber loop cavity of the CRD system. A modulated laser source was used to send pulses down into the fiber loop cavity and an erbium-doped fiber amplifier (EDFA) was placed in the fiber ring to provide an observable signal with a reasonable decay time. The behavior of the sensing head to temperature was studied due to its intrinsic sensitivity to said parameter - a sensitivity of -1.6×10-9 μs/°C was attained. This allowed eliminating the temperature component from RI measurement of water and a linear sensitivity of 580 μs/RIU in the RI range of 1.324-1.331 was obtained. The use of a MMI fiber sensor in the proposed CRD configuration allowed achieving a sensitivity ∼4-fold than that obtained with a tilted fiber Bragg grating and ∼2-fold than that when a micrometric channel inscribed in the fiber was used.

  1. Flex-gear power transmission system for transmitting EMF between Sun and ring gears

    Vranish, John M. (Inventor)


    A plurality of flexible cylindrical members, termed flex-gears and having gear tooth type perimeters are located in an annular space between two concentric rotating gear members, one an inner gear member and the other an outer ring gear member, both of which have mutually facing toothed surfaces which engage the flex-gears. The flex-gears rotate and orbit around the annular space as planetary gears when the inner and outer gear members rotate with respect to one another. Pairs of these elements located in two mutually parallel planes and separated by insulators provide two electrical conductor paths across which an electrical signal source, AC or DC, can be connected and coupled to an electrical device. Alternatively, one set of elements including outer gears segmented into mutually insulated semicircles and inner gears segmented into mutually insulated quadrants can be used.

  2. The orbits of the uranian satellites and rings, the gravity field of the uranian system, and the orientation of the pole of Uranus

    Jacobson, R. A., E-mail: [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91109-8099 (United States)


    French et al. determined the orbits of the Uranian rings, the orientation of the pole of Uranus, and the gravity harmonics of Uranus from Earth-based and Voyager ring occultations. Jacobson et al. determined the orbits of the Uranian satellites and the masses of Uranus and its satellites from Earth-based astrometry and observations acquired with the Voyager 2 spacecraft; they used the gravity harmonics and pole from French et al. Jacobson and Rush reconstructed the Voyager 2 trajectory and redetermined the Uranian system gravity parameters, satellite orbits, and ring orbits in a combined analysis of the data used previously augmented with additional Earth-based astrometry. Here we report on an extension of that work that incorporates additional astrometry and ring occultations together with improved data processing techniques.

  3. Non-contacting fluid ring seal systems for railcar axle bearing systems: Quarterly progress report No. 1, June 15 to September 15, 1987


    The main objectives of this DOE contract is the technical development of a practical, cost effective Fluid Ring seal system capable of: Drastically reducing locomotive drawbar traction power requirements by lowering seal friction losses prevalent in present railcar axle bearing systems; increasing reliability and safety of railroad cars by minimizing bearing lubricant leakage and minimizing bearing ''hot boxes''; and improving the productivity of the railway transportation systems by reducing rolling stock ''outages'' due to long seal life. 14 refs.

  4. Non-contacting fluid ring seal systems for railcar axle bearing systems: Quarterly progress report No. 4, March 16-June 15, 1988


    The main objectives of this DOE contract is the technical development of a practical, cost effective Fluid Ring seal system capable of: Drastically reducing locomotive drawbar traction power requirements by lowering seal friction losses prevalent in present railcar axle bearing systems; increasing reliability and safety of railroad cars by minimizing bearing lubricant leakage and minimizing bearing ''hot boxes''; and improving the productivity of the railway transportation systems by reducing rolling stock ''outages'' due to long seal life. Listed in this report are the seal test data.

  5. Topological rings

    Warner, S


    This text brings the reader to the frontiers of current research in topological rings. The exercises illustrate many results and theorems while a comprehensive bibliography is also included. The book is aimed at those readers acquainted with some very basic point-set topology and algebra, as normally presented in semester courses at the beginning graduate level or even at the advanced undergraduate level. Familiarity with Hausdorff, metric, compact and locally compact spaces and basic properties of continuous functions, also with groups, rings, fields, vector spaces and modules, and with Zorn''s Lemma, is also expected.

  6. Simulations of a dual TOF detector system for isochronous mass spectrometry in the collector ring at FAIR

    Diwisch, Marcel; Kuzminchuk-Feuerstein, Natalia [Justus-Liebig-Universitaet Giessen (Germany); Dickel, Timo; Geissel, Hans; Knoebel, Ronja; Plass, Wolfgang; Scheidenberger, Christoph [Justus-Liebig-Universitaet Giessen (Germany); GSI, Darmstadt (Germany); Weick, Helmut [GSI, Darmstadt (Germany)


    Direct mass measurements of short-lived exotic nuclei yield key information for modern nuclear physics. Experimentally determined mass values of exotic nuclei have a big impact on numerous applications in fundamental and applied science. With the Superconducting-Fragment Separator (Super-FRS) at the new FAIR facility a whole new range of exotic nuclei far away from stability will be accessible. Higher beam intensities and larger phase space volumes impose new challenges for the detection systems. To measure masses of short-lived exotic nuclei one can use the Isochronous Mass Spectrometry (IMS) which presently is successfully performed at the FRS-ESR facility. For IMS in the future Collector Ring, (CR) a first version of a new dual Time-Of-Flight (TOF) detector system, which fulfills the requirements of the new beam parameters has been designed. Simulation results for the new TOF detector in the CR will be shown.

  7. Effect of wettability of Wilhelmy plate and du Nouey ring on interfacial tension measurements in solvent extraction systems

    Gaonkar, A.G.; Neuman, R.D.


    The interfacial tension, ..gamma.., of di(2-ethylhexyl)phosphoric acid/n-dodecane/0.0010 N HCl systems was investigated at 20/sup 0/C to develop appropriate experimental techniques for use in liquid-liquid solvent extraction studies. The stringent precautions and purification procedures necessary to ensure that the system is free from interfering surface-active impurities are discussed. The Wilhelmy plate method was found to be superior to the du Nouey ring technique. Sandblasted glass plates gave reliable and reproducible values of ..gamma... However, with sandblasted platinum plates, increasingly lower ..gamma.. values were obtained with higher HDEHP concentrations. This behavior was attributed to the change in the wetting characteristics of the platinum plate by the adsorption of HDEHP on the platinum plate during its passage through the n-dodecane phase containing HDEHP. 30 references, 4 figures.

  8. Compact and broadband circularly polarized ring antenna with wide beam-width for multiple global navigation satellite systems

    Zhang Hong-Lin; Hu Bin-Jie; Zhang Xiu-Yin


    A compact and broadband circularly polarized (CP) annular ring antenna with wide beam-width is proposed for multiple global navigation satellite systems (GNSS) in the L1 band.The annular ring is excited by two modified L-probes with quadrature phase difference.It has a 36.3% 10-dB return loss bandwidth and a 13% 3-dB axial ratio bandwidth,because of the orthogonal L-probes with 90° phase difference.The measured peak gain of the antenna is 3.9 dBic.It can detect the satellites at lower elevation as its half power beam-width (HPBW) is 113° in both the x-z and y-z planes,achieving a cross-polarization level of larger than 25 dB.Noticeably,the antenna achieves 89% size reduction compared with the conventional half wavelength patch antennas.It can be used in hand-held navigation devices of multiple GNSS such as COMPASS,Galileo,GPS and GLONASS.

  9. A ring/disk/outflow system associated with W51 North: a very massive star in the making

    Zapata, Luis A; Schilke, Peter; Rodríguez, Luis F; Menten, Karl; Palau, Aina; Garrod, Robin


    Sensitive and high angular resolution ($\\sim$ 0.4\\arcsec) SO$_2$[22$_{2,20}$ $\\to$ 22$_{1,21}$] and SiO[5$\\to$4] line and 1.3 and 7 mm continuum observations made with the Submillimeter Array (SMA) and the Very Large Array (VLA) towards the young massive cluster W51 IRS2 are presented. We report the presence of a large (of about 3000 AU) and massive (40 M$_\\odot$) dusty circumstellar disk and a hot gas molecular ring around a high-mass protostar or a compact small stellar system associated with W51 North. The simultaneous observations of the silicon monoxide molecule, an outflow gas tracer, further revealed a massive (200 M$_\\odot$) and collimated ($\\sim14^\\circ$) outflow nearly perpendicular to the dusty and molecular structures suggesting thus the presence of a single very massive protostar with a bolometric luminosity of more than 10$^5$ L$_\\odot$. A molecular hybrid LTE model of a Keplerian and infalling ring with an inner cavity and a central stellar mass of more than 60 M$_\\odot$ agrees well with the SO...

  10. Compact stellar systems in the polar ring galaxies NGC 4650A and NGC 3808B: Clues to polar disk formation

    Ordenes-Briceño, Yasna; Puzia, Thomas H; Goudfrooij, Paul; Arnaboldi, Magda


    Polar ring galaxies (PRGs) are composed of two kinematically distinct and nearly orthogonal components, a host galaxy (HG) and a polar ring/disk (PR). The HG usually contains an older stellar population than the PR. The suggested formation channel of PRGs is still poorly constrained. Suggested options are merger, gas accretion, tidal interaction, or a combination of both. To constrain the formation scenario of PRGs, we study the compact stellar systems (CSSs) in two PRGs at different evolutionary stages: NGC 4650A with well-defined PR, and NGC 3808B, which is in the process of PR formation. We use archival HST/WFPC2 imaging. PSF-fitting techniques, and color selection criteria are used to select cluster candidates. Photometric analysis of the CSSs was performed to determine their ages and masses using stellar population models at a fixed metallicity. Both PRGs contain young CSSs ($< 1$ Gyr) with masses of up to 5$\\times$10$^6$M$_\\odot$, mostly located in the PR and along the tidal debris. The most massive ...

  11. Saturn's ``Gossamer'' Ring: The F Ring's Inner Sheet

    Showalter, M. R.; Burns, J. A.; Hamilton, D. P.


    Recent Galileo and Earth-based images have revealed for the first time that Jupiter's ``gossamer'' ring is actually composed of two rings, one bounded at the outer edge by Amalthea and the other bounded by Thebe. Dynamical models suggest that these rings are composed of dust grains ejected off the surfaces of the two moons, which then evolve inward under Poynting-Robertson drag. A very faint sheet of material filling the region between Saturn's A and F Rings reported by Burns et al. (BAAS 15, 1013--1014, 1983) may be a dynamically analogous system, in which dust escapes from the F Ring and evolves inward to the A Ring. Unlike Jupiter's gossamer rings, however, the inner sheet of Saturn's F Ring has been well observed from a large range of phase angles and visual wavelengths by Voyager. Voyager images reveal that this faint ring shows a tenfold increase in brightness between phase angles of 125(deg) and 165(deg) , indicating that it is composed of fine dust microns in size. Preliminary estimates of the normal optical depth fall in the range 1--2*E(-4) , depending on the dust size distribution assumed. Initial spectrophotometry reveals that the ring is neutral in color. The ring is uniform in brightness over the entire region between the two rings, with no evidence for internal structure associated with Prometheus and Atlas, suggesting that neither of these embedded moons acts as either a source or a sink. We will refine the aforementioned measurements and develop photometric models to better constrain the properties of the dust in this ring. This will enable us to relate the dust population to that in the F Ring proper, and to better explore the dynamical processes at work.

  12. Two dimensional fluoride ion conductor RbSn {2}F {5} studied by impedance spectroscopy and {19}F, {119}Sn, and {87}Rb NMR

    Yamada, K.; Ahmad, M. M.; Ogiso, Y.; Okuda, T.; Chikami, J.; Miehe, G.; Ehrenberg, H.; Fuess, H.


    RbSn2F5 is a two-dimensional fluoride ion conductor. It undergoes a first-order phase transition to a superionic state at 368 K. The structure of the low temperature phase has been determined from the Rietveld analysis of the X-ray powder diffraction. The dynamic properties of the fluoride ions in RbSn2F5 have been studied by impedance spectroscopy and solid state NMR. The dc ionic conductivity of this sample shows an abrupt increase at the phase transition temperature. We have obtained the hopping frequency and the concentration of the charge carriers (F- ions) at different temperatures from the analysis of the conductivity spectra using Almond-West formalism. The estimated values of the charge carriers’ concentration agree well with that determined from the structure and were found to be independent of temperature. The relatively small value of the power-law exponent, n ≈ 0.55, supports the two-dimensional property of the investigated material. Furthermore, 19F NMR with simulation has suggested the diffusive motions of the fluoride ions between different sites. In contrast, 119Sn and 87Rb NMR spectra below 250 K supported the intrinsic disordered nature due to the random distribution of the fluoride ion vacancies.

  13. Rectangular Ring Antenna Excited by Circular Disc Monopole for WiMAX System

    Souphanna Vongsack


    Full Text Available This research presents a rectangular ring antenna excited by a circular disc monopole (CDM mounted in front of a square reflector. The proposed antenna is designed to cover a frequency range of 2.300–5.825 GHz and thereby is suitable for WiMAX applications. Multiple parametric studies were carried out using the CST Microwave Studio simulation program. A prototype antenna was fabricated and experimented. The measurements were taken and compared with the simulation results, which indicates good agreement between both results. The prototype antenna produces an impedance bandwidth (|S11| < −10 dB that covers the WiMAX frequency range and a constant unidirectional radiation pattern (θ=0° and ∅=90°. The minimum and maximum gains are 3.7 and 8.7 dBi, respectively. The proposed antenna is of compact size and has good unidirectional radiation performance. Thus, it is very suitable for a multitude of WiMAX applications.

  14. Kernel representations for behaviors over finite rings

    Kuijper, M.; Pinto, R.; Polderman, J.W.; Yamamoto, Y.


    In this paper we consider dynamical systems finite rings. The rings that we study are the integers modulo a power of a given prime. We study the theory of representations for such systems, in particular kernel representations.

  15. Ring interferometry

    Malykin, Grigorii B; Zhurov, Alexei


    This monograph is devoted to the creation of a comprehensive formalism for quantitative description of polarized modes' linear interaction in modern single-mode optic fibers. The theory of random connections between polarized modes, developed in the monograph, allows calculations of the zero shift deviations for a fiber ring interferometer. The monograph addresses also the

  16. The Leo Archipelago: A System of Earth-Rings for Communications, Mass-Transport to Space, Solar Power, and Control of Global Warming

    Meulenberg, Andrew


    A multi-purpose low-earth-orbit system of rings circling the earth - the "LEO ARCHIPELAGO" - is proposed as a means of solving or bypassing many major problems hindering man's quest to get into space. A fiber-optic ring about the earth would be an initial testing and developmental stage for the ring systems, while providing cash-flow through a LEO-based, high-band-width, world-wide communication system. A Low-Earth-Orbit-based space-elevator system, "Sling-on-a-Ring," is proposed as the crucial developmental stage of the LEO Archipelago. Being a LEO-based heavy-mass lifter, rather than earth- or GEO-based, it is much less massive and therefore less costly than other proposed space-elevators. With the advent of lower-cost, higher-mass transport to orbit, the options for further space development (e.g., communications, space solar power, radiation dampers, sun shades, and permanent LEO habitation) are greatly expanded. This paper provides an update of the Sling-on-a-Ring concept in terms of new materials, poten...

  17. On SAP-rings

    Zhixiang, Wu


    The rings whose simple right modules are absolutely pure are called right $SAP$-rings. We give a new characterization of right $SAP$ rings, right $V$ rings, and von Neumann regular rings. We also obtain a new decomposition theory of right selfinjective von Neumann regular rings. The relationships between $SAP$-rings, $V$-rings, and von Neumann regular rings are explored. Some recent results obtained by Faith are generalized and the results of Wu-Xia are strengthened.

  18. Study of function response of a detector HPGe to photons of reaction {sup 19}F(p,{alpha}{gamma}){sup 16}O; Estudo da funcao resposta de um detetor HPGe a fotons da reacao {sup 19}F(p,{alpha}{gamma}){sup 16}O

    Tridapalli, D.B


    In the {sup 19}F(p,{alpha}{gamma}){sup 16}O reaction, characteristic gamma-rays with energies: 6.1 MeV; 6.9 MeV and 7.1 keV can be observed. These photons can be used in many important applications such as Proton Induced Gamma-ray Emission (PIGE), gamma radiography and calibration purposes. It has another advantage in calibration procedures, which is the observed photon flux is greater than other reactions studied, {sup 27}Al(p,{alpha}{gamma}){sup 28}Si and {sup 23}Na(p,{alpha}{gamma}){sup 24}Mg. In our laboratory, we are studying the efficiency and response function of HPGe detectors for high energy photons, and for this it is necessary a source with a level scheme with few gamma-ray transitions and known relative yields. The {sup 19}F(p,{alpha}{gamma}){sup 16}O reaction satisfies the first condition but in the literature we found relative yields for thick targets or reaction cross section for thin targets. However, we use targets of intermediate thickness, therefore in this work we measure the relative gamma-ray yields for protons with energies between 1.36 MeV and 1.42 MeV. The experiments were performed at the 1.7 MV Pelletron tandem accelerator of the Laboratorio de Analise de Materiais por Feixes Ionicos (LAMFI) located at Instituto de Fisica da Universidade de Sao Paulo, using a reverse-electrode closed-end coaxial HPGe detector with 72.5 mm in diameter and 60.5 mm in length, at 0 deg. The proton irradiation current was 50 nA, and the target consisted of 250 {mu}g/cm{sup 2} CaF{sub 2} evaporated on a 0.1 mm Ta backing. In this reaction the {sup 20}Ne resonant state fissions in flight, and the resulting {sup 16}O excited states have different half-lives; all observed peaks are deformed due to either Doppler broadening from {sup 16}O random velocity direction or Doppler shift from nuclei that leave the target toward the vacuum chamber. Moreover, the peak deformations vary with the proton energy. These deformations were modeled by a Monte Carlo simulation that

  19. Cooperative activation of cyclobutanones and olefins leads to bridged ring systems by a catalytic [4 + 2] coupling

    Ko, Haye Min; Dong, Guangbin


    Bridged ring systems are widely found in natural products, and successful syntheses of them frequently feature intramolecular Diels-Alder reactions. These reactions are subclassified as either type I or type II depending on how the diene motif is tethered to the rest of the substrate (type I are tethered at the 1-position of the diene and type II at the 2-position). Although the type I reaction has been used with great success, the molecular scaffolds accessible by the type II reactions are limited by the strain inherent in the formation of an sp2 carbon at a bridgehead position. Here, we describe a complementary approach that provides access to these structures through the C-C activation of cyclobutanones and their coupling with olefins. Various alkenes have been coupled with cyclobutanones to provide a range of bridged skeletons. The ketone group of the products serves as a convenient handle for downstream functionalization.

  20. Removal of copper and iron by polyurethane foam column in FIA system for the determination of nickel in pierced ring.

    Vongboot, Monnapat; Suesoonthon, Monrudee


    Polyurethane foam (PUF) mini-column was used to eliminate copper and iron for the determination of nickel in pierced rings. The PUF mini-column was connected to FIA system for on-line sorption of copper and iron in complexes form of CuSCN(+) and FeSCN(2+). For this season, the acid solution containing a mixture of Ni(II), Fe(III), Cu(II) and SCN(-) ions was firstly flew into the PUF column. Then, the percolated solution which Fe(III) and Cu(II) ions is separated from analysis was injected into FIA system to react with 4-(2-pyridylazo) resorcinol (PAR) reagent in basic condition which this method is called pH gradient technique. The Ni-PAR complexes obtained were measured theirs absorbance at 500 nm by UV visible spectrophotometer. In this study, it was found that Cu(II) and Fe(III) were completely to form complexes with 400 mmol/L KSCN and entirely to eliminate in acidic condition at pH 3.0. In the optimum condition of these experiments, the method provided the linear relationship between absorbance and the concentration of Ni(II) in the range from 5.00 to 30.00 mg/L. Linear equation is y=0.0134x+0.0033 (R(2)=0.9948). Precision, assessed in the term of the relative standard deviation, RSD, and accuracy for multiple determinations obtained in values of 0.77-1.73% and 97.4%, respectively. The level of an average amount of Ni(II) in six piercing rings was evaluated to be 14.78 mg/g.

  1. Decay ring design

    Chancé, A; Bouquerel, E; Hancock, S; Jensen, E

    The study of the neutrino oscillation between its different flavours needs pureand very intense fluxes of high energy, well collimated neutrinos with a welldetermined energy spectrum. A dedicated machine seems to be necessarynowadays to reach the required flux. A new concept based on the β-decayof radioactive ions which were accelerated in an accelerator chain was thenproposed. After ion production, stripping, bunching and acceleration, the unstableions are then stored in a racetrack-shaped superconducting decay ring.Finally, the ions are accumulated in the decay ring until being lost. The incomingbeam is merged to the stored beam by using a specific RF system, whichwill be presented here.We propose here to study some aspects of the decay ring, such as its opticalproperties, its RF system or the management of the losses which occur in thering (mainly by decay or by collimation).

  2. (d ,n ) proton-transfer reactions on 9Be, 11B, 13C, N,1514, and 19F and spectroscopic factors at Ed=16 MeV

    Febbraro, M.; Becchetti, F. D.; Torres-Isea, R. O.; Riggins, J.; Lawrence, C. C.; Kolata, J. J.; Howard, A. M.


    The (d ,n ) reaction has been studied with targets of 9Be, 11B, 13C, N,1514, and 19F at Ed=16 MeV using a deuterated liquid-scintillator array. Advanced spectral unfolding techniques with accurately measured scintillator response functions were employed to extract neutron energy spectra without the need for long-path neutron time-of-flight. An analysis of the proton-transfer data at forward angles to the ground states of the final nuclei, using finite-range distorted-wave Born approximation analysis with common bound-state, global, and local optical-model parameter sets, yields a set of self-consistent spectroscopic factors. These are compared with the results of several previous time-of-flight measurements, most done many years ago for individual nuclei at lower energy and often analyzed using zero-range transfer codes. In contrast to some of the earlier published data, our data generally compare well with simple shell-model predictions, with little evidence for uniform quenching (reduction from shell-model values) that has previously been reported from analysis of nucleon knock-out reactions. Data for low-lying excited states in 14N from 13C(d ,n ) also is analyzed and spectroscopic information relevant to nuclear astrophysics obtained. A preliminary study of the radioactive ion beam induced reaction 7Be(d ,n ) , E (7Be)=30 MeV was carried out and indicates further improvements are needed for such measurements, which require detection of neutrons with En<2 MeV .

  3. Implementing Digital Feedback Controls for the Multiple Simultaneous Ring Cavities in the FASOR-X System


    choices for gains and detector saturation and trip levels critically important. For example, some absorption within the LBO crystal or its heated...the chiller ; 2) activate the SFG heater; 3) turn on the Main System Software via a single click and wait 10-20 minutes for the system to produce

  4. Magnetization of two coupled rings

    Avishai, Y [Department of Physics and Ilse Katz Center for Nanotechnology, Ben Gurion University, Beer Sheva 84105 (Israel); Luck, J M [Institut de Physique Theorique, IPhT, CEA Saclay, and URA 2306, CNRS, 91191 Gif-sur-Yvette cedex (France)], E-mail:, E-mail:


    We investigate the persistent currents and magnetization of a mesoscopic system consisting of two clean metallic rings sharing a single contact point in a magnetic field. Many novel features with respect to the single-ring geometry are underlined, including the explicit dependence of wavefunctions on the Aharonov-Bohm fluxes, the complex pattern of two-fold and three-fold degeneracies, the key role of length and flux commensurability, and in the case of commensurate ring lengths the occurrence of idle levels which do not carry any current. Spin-orbit interactions, induced by the electric fields of charged wires threading the rings, give rise to a peculiar version of the Aharonov-Casher effect where, unlike for a single ring, spin is not conserved. Remarkably enough, this can only be realized when the Aharonov-Bohm fluxes in both rings are neither integer nor half-integer multiples of the flux quantum.

  5. Saturn's Rings and Associated Ring Plasma Cavity: Evidence for Slow Ring Erosion

    Farrell, W. M.; Kurth, W. S.; Gurnett, D. A.; Persoon, A. M.; MacDowall, R. J.


    We re-examine the radio and plasma wave observations obtained during the Cassini Saturn orbit insertion period, as the spacecraft flew over the northern ring surface into a radial distance of 1.3 Rs (over the C-ring). Voyager era studies suggest the rings are a source of micro-meteoroid generated plasma and dust, with theorized peak impact-created plasma outflows over the densest portion of the rings (central B-ring). In sharp contrast, the Cassini Radio and Plasma Wave System (RPWS) observations identify the presence of a ring-plasma cavity located in the central portion of the B-ring, with little evidence of impact-related plasma. While previous Voyager era studies have predicted unstable ion orbits over the C- ring, leading to field-aligned plasma transport to Saturns ionosphere, the Cassini RPWS observations do not reveal evidence for such instability-created plasma fountains. Given the passive ring loss processes observed by Cassini, we find that the ring lifetimes should extend >10(exp 9) years, and that there is limited evidence for prompt destruction (loss in <100 Myrs).

  6. A microcomputer-based data acquisition and control system for the direct shear, ring shear, triaxial shear, and consolidation tests

    Powers, Philip S.


    This report is intended to provide internal documentation for the U.S. Geological Survey laboratory's automatic data acquisition system. The operating procedures for each type of test are designed to independently lead a first-time user through the various stages of using the computer to control the test. Continuing advances in computer technology and the availability of desktop microcomputers with a wide variety of peripheral equipment at a reasonable cost can create an efficient automated geotechnical testing environment. A geotechnical testing environment is shown in figure 1. Using an automatic data acquisition system, laboratory test data from a variety of sensors can be collected, and manually or automatically recorded on a magnetic device at the same apparent time. The responses of a test can be displayed graphically on a CRT in a matter of seconds, giving the investigator an opportunity to evaluate the test data, and to make timely, informed decisions on such matters as whether to continue testing, abandon a test, or modify procedures. Data can be retrieved and results reported in tabular form, or graphic plots, suitable for publication. Thermistors, thermocouples, load cells, pressure transducers, and linear variable differential transformers are typical sensors which are incorporated in automated systems. The geotechnical tests which are most practical to automate are the long-term tests which often require readings to be recorded outside normal work hours and on weekends. Automation applications include incremental load consolidation tests, constant-rate-of-strain consolidation tests, direct shear tests, ring shear tests, and triaxial shear tests.

  7. A low-cost dielectric spectroscopic system using metamaterial open horn-ring resonator-inspired BSF and detection circuitry

    Kumari, Ratnesh; Patel, Piyush N.


    The sensitivity in a lower microwave band dielectric spectroscopic system is relatively less compared to that of millimeter wave and terahertz system. This work reports modeling and development of an epsilon-negative metamaterial resonator-inspired microwave band-stop filter as a prototype device and its detection circuitry for the spectroscopic analysis of dielectric samples in S-band. The device structure consists of a diamond-shaped patch with a complementary open split horn-ring resonator, fabricated on a Neltech substrate of relative permittivity ( ɛ r = 3.2). The measured transmission coefficient at 2.2 GHz and simulated result at 2.24 GHz demonstrate an excellent accuracy in the device fabrication. A low-cost connector-type microwave signal detection system was assembled for the real-time transduction of device signal into an equivalent DC voltage. Further, a single channel cavity developed using polydimethylsiloxane was placed over the resonator gap for analyzing the perturbation effect of electric field intensity on the resonance and circuit output DC level for different dielectric samples under test. The performed calibrations show linearity up to 82.5 % in the device response.

  8. Constructions over localizations of rings

    Alessandro Logar


    Full Text Available In this paper we construct a category of effective noetherian rings in which linear equations can be “solved”. This category is closed with respect to some important constructions like trascendental extensions, quotientations, finite products and localizations with respect to a large class of multiplicatively closed systems. Hence it gives a definition of “constructive” rings.

  9. Total synthesis and evaluation of vinblastine analogues containing systematic deep-seated modifications in the vindoline subunit ring system: core redesign.

    Schleicher, Kristin D; Sasaki, Yoshikazu; Tam, Annie; Kato, Daisuke; Duncan, Katharine K; Boger, Dale L


    The total synthesis of a systematic series of vinblastine analogues that contain deep-seated structural modifications to the core ring system of the lower vindoline subunit is described. Complementary to the vindoline 6,5 DE ring system, compounds with 5,5, 6,6, and the reversed 5,6 membered DE ring systems were prepared. Both the natural cis and unnatural trans 6,6-membered ring systems proved accessible, with the latter representing a surprisingly effective class for analogue design. Following Fe(III)-promoted coupling with catharanthine and in situ oxidation to provide the corresponding vinblastine analogues, their evaluation provided unanticipated insights into how the structure of the vindoline subunit contributes to activity. Two potent analogues (81 and 44) possessing two different unprecedented modifications to the vindoline subunit core architecture were discovered that matched the potency of the comparison natural products and both lack the 6,7-double bond whose removal in vinblastine leads to a 100-fold drop in activity.

  10. Simulation of a ring resonator-based optical beamformer system for phased array receive antennas

    Tijmes, M.R.; Meijerink, Arjan; Roeloffzen, C.G.H.; Bentum, Marinus Jan


    A new simulator tool is described that can be used in the field of RF photonics. It has been developed on the basis of a broadband, continuously tunable optical beamformer system for phased array receive antennas. The application that is considered in this paper is airborne satellite reception of di

  11. Simulation of a ring-resonator based optical beamformer system for phased array receive antennas

    Tijmes, M.R.; Meijerink, A.; Bentum, M.J.; Roeloffzen, C.G.H.


    A new simulator tool is described that can be used in the field of RF photonics. It has been developed on the basis of a broadband, continuously tunable optical beamformer system for phased array receive antennas. The application that is considered in this paper is airborne satellite reception of di

  12. Pericyclic and related rearrangements for the synthesis of nitrogen heterocyclic ring systems


    The thesis describes synthesis and reactions of allene azides tethered to various functional groups and the application of the discovered cascade transformations towards the synthesis of radianspene J model system. Chapter 1 covers reactions of simple allene azides containing alkyl and cycloalkyl substituents. Thermal rearrangements of these substrates delivered isocyanides and azadienes via the proposed azatrimethylenemethane (ATMM) intermediates. On the other hand, vinylidenecycloprop...

  13. A 166.6 MHz superconducting rf system for the HEPS storage ring

    Zhang, P.; Hao, X.; Huang, T.; Li, Z.; Lin, H.; Meng, F.; Mi, Z.; Sun, Y.; Wang, G.; Wang, Q.; Zhang, X.


    A superconducting 166.6 MHz quarter-wave beta=1 cavity was recently proposed for the High Energy Photon Source (HEPS), a 6 GeV kilometer-scale light source. Four 166.6 MHz cavities will be used for main acceleration in the newly planned on-axis beam injection scheme realized by a double-frequency RF system. The fundamental frequency, 166.6 MHz, was dictated by the fast injection kicker technology and the preference of using 499.8 MHz SC RF cavity as the third harmonic. Each 166.6 MHz cavity will be operated at 4.2 K providing 1.2 MV accelerating voltage and 150 kW of power to the electron beam. The input coupler will use single-window coaxial type graded up to 200 kW CW power. Each cavity will be equipped with a 200 kW solid-state amplifier and digital low-level RF system. This paper describes the 166.6 MHz RF system with a focus on the design and optimization of the RF cavity and its ancillaries, the LLRF system and the status of the solid-state amplifiers.

  14. Rings from Close Encounters

    Kohler, Susanna


    Weve recently discovered narrow sets of rings around two minor planets orbiting in our solar system. How did these rings form? A new study shows that they could be a result of close encounters between the minor planets and giants like Jupiter or Neptune.Unexpected Ring SystemsPositions of the centaurs in our solar system (green). Giant planets (red), Jupiter trojans (grey), scattered disk objects (tan) and Kuiper belt objects (blue) are also shown. [WilyD]Centaurs are minor planets in our solar system that orbit between Jupiter and Neptune. These bodies of which there are roughly 44,000 with diameters larger than 1 km have dynamically unstable orbits that cross paths with those of one or more giant planets.Recent occultation observations of two centaurs, 10199 Chariklo and 2060 Chiron, revealed that these bodies both host narrow ring systems. Besides our four giant planets, Chariklo and Chiron are the only other bodies in the solar system known to have rings. But how did these rings form?Scientists have proposed several models, implicating collisions, disruption of a primordial satellite, or dusty outgassing. But a team of scientists led by Ryuki Hyodo (Paris Institute of Earth Physics, Kobe University) has recently proposed an alternative scenario: what if the rings were formed from partial disruption of the centaur itself, after it crossed just a little too close to a giant planet?Tidal Forces from a GiantHyodo and collaborators first used past studies of centaur orbits to estimate that roughly 10% of centaurs experience close encounters (passing within a distance of ~2x the planetary radius) with a giant planet during their million-year lifetime. The team then performed a series of simulations of close encounters between a giant planet and a differentiated centaur a body in which the rocky material has sunk to form a dense silicate core, surrounded by an icy mantle.Some snapshots of simulation outcomes (click for a closer look!) for different initial states of

  15. Simulating Excited State Dynamics in Systems with Multiple Avoided Crossings Using Mapping Variable Ring Polymer Molecular Dynamics.

    Duke, Jessica R; Ananth, Nandini


    Mapping variable ring polymer molecular dynamics (MV-RPMD) is an approximate quantum dynamics method based on imaginary-time path integrals for simulating electronically nonadiabatic photochemical processes. By employing a mapping protocol to transform from a discrete electronic state basis to continuous Cartesian phase-space variables, the method captures electronic state transitions coupled to nuclear motion using only classical MD trajectories. In this work, we extend the applicability of MV-RPMD to simulations of photoinduced excited electronic state dynamics in nonadiabatic systems with multiple avoided crossings. We achieve this by deriving a new electronic state population estimator in the phase space of electronic variables that is exact at equilibrium and numerically accurate in real time. Further, we introduce an efficient constraint protocol to initialize an MV-RPMD simulation to a particular electronic state. We numerically demonstrate the accuracy of this estimator and constraint technique in describing electronic state dynamics from an initial nonequilibrium state in six model systems, three of which describe photodissociation.

  16. A free-flowing soap film combined with cavity ring-down spectroscopy as a detection system for liquid chromatography.

    Vogelsang, Markus; Welsch, Thomas; Jones, Harold


    We have shown that a free-flowing soap film has sufficiently high-quality optical properties to allow it to be used in the cavity of a ring-down spectrometer (CRDS). The flow rates required to maintain a stable soap film were similar to those used in liquid chromatography and thus allowed interfacing with an HPLC system for use as an optical detector. We have investigated the properties of the system in a relevant analytical application. The soap film/CRDS combination was used at 355 nm as a detector for the separation of a mixture of nitroarenes. These compounds play a role in the residue analysis of areas contaminated with explosives and their decomposition products. In spite of the short absorption path length (9 microm) obtained by the soap film, the high-sensitivity of CRDS allowed a limit of detection of 4 x 10(-6) in absorption units (AU) or less than 17 fmol in the detection volume to be achieved.

  17. An ultra low-noise AC beam transformer and digital signal processing system for CERN's ELENA ring

    Angoletta, M E; Caspers, F; Federmann, S; Molendijk, J; Pedersen, F; Sanchez-Quesada, J


    CERN’s Extra Low ENergy Antiproton (ELENA) ring is a new synchrotron that will be commissioned in 2016 to further decelerate the antiprotons coming from CERN’s Antiproton Decelerator (AD). Essential longitudinal diagnostics required for commissioning and operation include the intensity measurement for bunched and debunched beams and the measurement of p/p for debunched beams to assess the electron cooling performance. The beam phase information is also needed by the Low-Level RF (LLRF) system. The baseline system for providing the required beam parameters and signals is based upon two ultra-low-noise AC beam transformers and associated digital signal processing. The AC beam transformers cover different frequency regions and are an adaptation to the ELENA layout of those used in the AD. Two AC beam transformers will also be installed in the extraction lines to provide beam intensity measurements. The digital signal processing will be carried out with the leadingedge hardware family used for ELENA’s L...

  18. Nonlinear analysis of ring oscillator circuits

    Ge, Xiaoqing


    Using nonlinear systems techniques, we analyze the stability properties and synchronization conditions for ring oscillator circuits, which are essential building blocks in digital systems. By making use of its cyclic structure, we investigate local and global stability properties of an n-stage ring oscillator. We present a sufficient condition for global asymptotic stability of the origin and obtain necessity if the ring oscillator consists of identical inverter elements. We then give a synchronization condition for identical interconnected ring oscillators.

  19. Preliminary design of the pulse generator for the CLIC damping ring extraction system

    Holma, Janne; Ovaska, Seppo


    The spent drive beam must be cleanly extracted and bent away from the decelerator axis at the end of each CLIC decelerator in order to leave space for injecting a fresh beam train in the next sector. Then the spent beam must be safely absorbed. A compact extraction system made of a single dipole is proposed. The spent beam is driven to a water dump located at 20m downstream of the extraction point and transversely 6m away of the axis of the main linac. An adequate spread of the beam impact map on the dump offers small temperature excursions in both the dump and its entrance window, allowing for reliable operation and a long lifetime of the system.

  20. The Search for Ringed Exoplanets

    Kohler, Susanna


    Are planetary rings as common in our galaxy as they are in our solar system? A new study demonstrates how we might search for ringed exoplanets and then possibly finds one!Saturns Elsewhere?Artists illustration of the super ring system around exoplanet J1407b. This is the only exoplanet weve found with rings, but its not at all like Saturn. [Ron Miller]Our solar system is filled with moons and planetary rings, so it stands to reason that exoplanetary systems should exhibit the same features. But though weve been in the planet-hunting game for decades, weve only found one exoplanet thats surrounded by a ring system. Whats more, that system J1407b has enormous rings that are vastly different from the modest, Saturn-like rings that we might expect to be more commonplace.Have we not discovered ringed exoplanets just because theyre hard to identify? Or is it because theyre not out there? A team of scientists led by Masataka Aizawa (University of Tokyo) has set out to answer this question by conducting a systematic search for rings around long-period planet candidates.The transit light curve of KIC 10403228, shown with three models: the best-fitting planet-only model (blue) and the two best-fitting planet+ring models (green and red). [Aizawa et al. 2017]The Hunt BeginsWhy long-period planets? Rings are expected to be unstable as the planet gets closer to the central star. Whats more, the planet needs to be far enough away from the stars warmth for the icy rings to exist. The authors therefore select from the collection of candidate transiting planets 89 long-period candidates that might be able to host rings.Aizawa and collaborators then fit single-planet models (with no rings) to the light curves of these planets and search for anomalies curves that arent fit well by these standard models. Particularly suspicious characteristics include a long ingress/egress as the planet moves across the face of the star, and asymmetry of the transit shape.After applying a series of

  1. Double-ring network model of the head-direction system

    Xie, Xiaohui; Hahnloser, Richard H.; Seung, H. Sebastian


    In the head-direction system, the orientation of an animal's head in space is encoded internally by persistent activities of a pool of cells whose firing rates are tuned to the animal's directional heading. To maintain an accurate representation of the heading information when the animal moves, the system integrates horizontal angular head-velocity signals from the vestibular nuclei and updates the representation of directional heading. The integration is a difficult process, given that head velocities can vary over a large range and the neural system is highly nonlinear. Previous models of integration have relied on biologically unrealistic mechanisms, such as instantaneous changes in synaptic strength, or very fast synaptic dynamics. In this paper, we propose a different integration model with two populations of neurons, which performs integration based on the differential input of the vestibular nuclei to these two populations. We mathematically analyze the dynamics of the model and demonstrate that with carefully tuned synaptic connections it can accurately integrate a large range of the vestibular input, with potentially slow synapses.

  2. Origami rings

    Buhler, Joe; de Launey, Warwick; Graham, Ron


    Motivated by a question in origami, we consider sets of points in the complex plane constructed in the following way. Let $L_\\alpha(p)$ be the line in the complex plane through $p$ with angle $\\alpha$ (with respect to the real axis). Given a fixed collection $U$ of angles, let $\\RU$ be the points that can be obtained by starting with $0$ and $1$, and then recursively adding intersection points of the form $L_\\alpha(p) \\cap L_\\beta(q)$, where $p, q$ have been constructed already, and $\\alpha, \\beta$ are distinct angles in $U$. Our main result is that if $U$ is a group with at least three elements, then $\\RU$ is a subring of the complex plane, i.e., it is closed under complex addition and multiplication. This enables us to answer a specific question about origami folds: if $n \\ge 3$ and the allowable angles are the $n$ equally spaced angles $k\\pi/n$, $0 \\le k < n$, then $\\RU$ is the ring $\\Z[\\zeta_n]$ if $n$ is prime, and the ring $\\Z[1/n,\\zeta_{n}]$ if $n$ is not prime, where $\\zeta_n := \\exp(2\\pi i/n)$ is ...

  3. On Necessary and Sufficient Conditions for Regulation of Linear Systems Over Rings,


    book (e.g., Bourbaki [1972, Chapt. 2]). Let (m&Ii, be the set of maximal ideals of k[z, zI] such that (2.11) rank [zl - F, G]g< n. After these...Khargonekar [1980], where a . theory of observers and coefficient assignment by causal dynamic state feedback was developed. Although the split condition is...this research was done when the author was at the Center for Mathematical System Theory , University of Florida, Gainesville. Florida 32611, and was

  4. Contraceptive vaginal ring (NuvaRing)-a novel, convenient and effective contraceptive option

    Chen Wei-lin; Fan Guang-sheng


    Contraceptive vaginal ring (NuvaRing) is a new combined hormonal contraceptive method.Each ring contains 2.7mg ethinyl estradiol (EE) and 11.7mg etonogestrel.The ring is characteristic with its ease of use,lower EE systemic exposure and excellent cycle control.Studies have demonstrated that the efficacy and safety of the ring are equivalent to combined oral contraceptive (COC).The side effects of the ring are fewer and the biocompatibility is good.Recent studies have proved that the NuvaRing is a new,effective hormonal contraceptive option for women.

  5. Near rings, fuzzy ideals, and graph theory

    Satyanarayana, Bhavanari


    Near Rings, Fuzzy Ideals, and Graph Theory explores the relationship between near rings and fuzzy sets and between near rings and graph theory. It covers topics from recent literature along with several characterizations. After introducing all of the necessary fundamentals of algebraic systems, the book presents the essentials of near rings theory, relevant examples, notations, and simple theorems. It then describes the prime ideal concept in near rings, takes a rigorous approach to the dimension theory of N-groups, gives some detailed proofs of matrix near rings, and discusses the gamma near

  6. Exciton interference revealed by energy dependent exciton transfer rate for ring-structured molecular systems

    Yan, Yun-An, E-mail: [Guizhou Provincial Key Laboratory of Computational Nanomaterial Science, Guizhou Education University, Guiyang, Guizhou 550018 (China)


    The quantum interference is an intrinsic phenomenon in quantum physics for photon and massive quantum particles. In principle, the quantum interference may also occur with quasi-particles, such as the exciton. In this study, we show how the exciton quantum interference can be significant in aggregates through theoretical simulations with hierarchical equations of motion. The systems under investigation are generalized donor-bridge-acceptor model aggregates with the donor consisting of six homogeneous sites assuming the nearest neighbor coupling. For the models with single-path bridge, the exciton transfer time only shows a weak excitation energy dependence. But models with double-path bridge have a new short transfer time scale and the excitation energy dependence of the exciton transfer time assumes clear peak structure which is detectable with today’s nonlinear spectroscopy. This abnormality is attributed to the exciton quantum interference and the condition for a clear observation in experiment is also explored.

  7. Dynamical decay of 32S* and 31P* formed in 20Ne+12C and 19F+12C reactions, respectively, at E*CN = 60 MeV

    Singh BirBikram


    Full Text Available The target-like C-yield in the decay of compound systems 32S* and 31P* formed in 20Ne+12C and 19F+12C reactions at E*CN=60 MeV, is studied for the contribution of fusion-fission (ff decay cross section σff and the deep inelastic (DI orbiting σorb from the compound nucleus (CN and non-compound nucleus nCN processes, respectively. The calculations are performed using the collective clusterization of fragments within the dynamical cluster-decay model (DCM of Gupta and collaborators. Besides studying the competition between ff and DI orbiting phenomenon in the C-yield of these systems, we exclusively investigate the preformation and barrier penetration probabilities P0 and P as a function of angular momentum ℓ values which subsequently affects the contributions of σff and σorb. For calculating the contribution of σff in the C-yield, we have added the contributions from all the minimized intermediate mass fragments (IMFs for Z=6 in the calculated fragmentation potentials for 32S* (IMFs 11,12,13C are minimized and for 31P* (IMFs 12,13C are minimized, while calculating subsequently, P0 and the P for these IMFs. The distribution of preformed clusters/fragments as a function of fragment mass visibly explore the nuclear structure effects for the C-yield in decay of these compound systems, wherein, it is shown to be more favoured in the decay of 31P* in comparison to 32S* decay. The contribution of σorb to the C-yield is calculated from P at different allowed ℓ-values (upto ℓmax and also P≤1 of the outgoing fragments (same as that in the entrance channel, i.e., P0=1. Though preliminary but useful results indicates the competition between the CN and nCN process in the C-yield for the compound system 32S* only while the decay of 31P* is of pure CN origin, as observed in the experimental study. The calculations are in good comparison with the available experimental data.

  8. Range Distribution Parameters and Electronic Stopping Power for 19F+ Ions in SnO2, Indium-Tin Oxide, AgGaSe2 and AgGaS2:Comparison Between Theory and Experiment

    XIA Hui-Hao; LIU Xiang-Dong


    @@ Range distributions of fluorine for 19F+- implantation into SnO2, indium-tin oxide, AgGaS2 and AgGaSe2 are measured by using the 1gF(p,αγ)16O resonant nuclear reactions. The electronic stopping cross sections for 19F ions in these materials are derived from the measured range distributions. These experimental results are compared with those obtained from the newest version of stopping and range computer code, SRIM2003. The values of projected range predicted by the SRIM2003 agree well with the measured values for AgGaS2 and AgGaSe2 substrates. However, the values given by the SRIM2003 substantially deviate from the experimental values for the oxide materials SnO2 and ITO.

  9. Formation of polar ring galaxies

    Bournaud, F


    Polar ring galaxies are peculiar systems in which a gas rich, nearly polar ring surrounds an early-type or elliptical host galaxy. Two formation scenarios for these objects have been proposed: they are thought to form either in major galaxy mergers or by tidal accretion of the polar material from a gas rich donor galaxy. Both scenarios are studied through N-body simulations including gas dynamics and star formation. Constraints on physical parameters are drawn out, in order to determine which scenario is the most likely to occur. Polar ring galaxies from each scenario are compared with observations and we discuss whether the accretion scenario and the merging scenario account for observational properties of polar ring galaxies. The conclusion of this study is that the accretion scenario is both the most likely and the most supported by observations. Even if the merging scenario is rather robust, most polar ring galaxies are shown to be the result of tidal gas accretion events.

  10. Polymorphism of collagen triple helix revealed by 19F NMR of model peptide [Pro-4(R)-hydroxyprolyl-Gly]3-[Pro-4(R)-fluoroprolyl-Gly]-[Pro-4(R)-hydroxyprolyl-Gly]3.

    Kawahara, Kazuki; Nemoto, Nobuaki; Motooka, Daisuke; Nishi, Yoshinori; Doi, Masamitsu; Uchiyama, Susumu; Nakazawa, Takashi; Nishiuchi, Yuji; Yoshida, Takuya; Ohkubo, Tadayasu; Kobayashi, Yuji


    We have characterized various structures of (Pro-Hyp(R)-Gly)(3)-Pro-fPro(R)-Gly-(Pro-Hyp(R)-Gly)(3) in the process of cis-trans isomerization and helix-coil transition by exploiting the sole (19)F NMR probe in 4(R)-fluoroproline (fPro(R)). Around the transition temperature (T(m)), we detected a species with a triple helical structure distinct from the ordinary one concerning the alignment of three strands. The (19)F-(19)F exchange spectroscopy showed that this misaligned and that the ordinary triple helices were interchangeable only indirectly via an extended monomer strand with all-trans peptide bonds at Pro-fPro(R), Pro-Hyp(R), and Gly-Pro in the central segment. This finding demonstrates that the helix-coil transition of collagen peptides is not described with a simple two-state model. We thus elaborated a scheme for the transition mechanism of (Pro-Hyp(R)-Gly)(n) that the most extended monomer strand can be the sole source both to the misaligned and correctly folded triple-helices. The staggered ends could help misaligned triple helices to self-assemble to higher-order structures. We have also discussed the possible relationship between the misaligned triple helix accumulating maximally at T(m) and the kinetic hysteresis associated with the helix-coil transition of collagen.

  11. Simultaneous determinations of a monofluorinated imidazo(1, 5-a)(1, 4)benzodiazepine and the corresponding benzophenone as a function of pH and in aqueous formulations by /sup 19/F nuclear magnetic resonance spectrometry

    Bhattacharyya, P.K.; Grant, A. (Hoffmann-La Roche, Inc., Nutley, NJ (USA). Quality Control Dept.)


    8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo(1, 5-a)(1, 4)benzodiazepine (called ''midazolam'') exists in equilibrium with the corresponding benzophenone (the ''open-Mng form''). The two compounds were determined simultaneously as a function of pH with /sup 19/F-n.m.r. spectrometry. In a unique application of /sup 19/F-n.m.r. spectrometry, the compounds are determined simultaneously in aqueous dosage forms without the need for the lowest concentration of sample used (approximately 1 mg ml/sup -1/) was 200:1 for 3000 scans. This was obtained by partial proton decoupling and exponential multiplication of the free induction decay with a line-broadening parameter of 12 Hz. Quantitative results are presented with a standard deviation of < 2.0% in the mean ratio of the two compounds. The results are also compared with those obtained by the spectrophotometric fluorescamine method. Advantages of the /sup 19/F-n.m.r. technique in this determination are discussed.

  12. GPU-based low-level trigger system for the standalone reconstruction of the ring-shaped hit patterns in the RICH Cherenkov detector of NA62 experiment

    Ammendola, R.; Biagioni, A.; Chiozzi, S.; Cretaro, P.; Cotta Ramusino, A.; Di Lorenzo, S.; Fantechi, R.; Fiorini, M.; Frezza, O.; Gianoli, A.; Lamanna, G.; Lo Cicero, F.; Lonardo, A.; Martinelli, M.; Neri, I.; Paolucci, P. S.; Pastorelli, E.; Piandani, R.; Piccini, M.; Pontisso, L.; Rossetti, D.; Simula, F.; Sozzi, M.; Vicini, P.


    This project aims to exploit the parallel computing power of a commercial Graphics Processing Unit (GPU) to implement fast pattern matching in the Ring Imaging Cherenkov (RICH) detector for the level 0 (L0) trigger of the NA62 experiment. In this approach, the ring-fitting algorithm is seedless, being fed with raw RICH data, with no previous information on the ring position from other detectors. Moreover, since the L0 trigger is provided with a more elaborated information than a simple multiplicity number, it results in a higher selection power. Two methods have been studied in order to reduce the data transfer latency from the readout boards of the detector to the GPU, i.e., the use of a dedicated NIC device driver with very low latency and a direct data transfer protocol from a custom FPGA-based NIC to the GPU. The performance of the system, developed through the FPGA approach, for multi-ring Cherenkov online reconstruction obtained during the NA62 physics runs is presented.

  13. Investigation of transient processes at the DELTA electron storage ring using a digital bunch-by-bunch feedback system

    Hoener, Markus


    At the 1.5-GeV synchrotron radiation source DELTA, operated by the TU Dortmund University, intensive synchrotron radiation in the spectral range from hard X-rays to THz radiation is generated by the circular deflection of highly relativistic electron bunches. Interacting with the vacuum chamber wall, the electron bunches create electric fields, which can act back on subsequent bunches. With increasing beam current, the excitation is enhanced so that the electron beam is unstable, which means that the electron bunches oscillate longitudinally or transversely relative to their reference position. The oscillations reduce the quality of the synchrotron radiation and limit the maximum storable beam current. Within the scope of this thesis, the beam instabilities at the storage ring were systematically investigated. A digital bunch-by-bunch feedback system was installed and commissioned, which allows to detect and digitize the position of each electron bunch at each turn. Based on the input signal, a correction signal is calculated in order to suppress transverse and longitudinal oscillation of the bunches. In addition, it is possible to excite dedicated bunches. The systematic excitation of all coupled-bunch modes allowed for the first time to determine the damping rates of all 192 eigenmodes of the electron beam. The current dependence of the damping rates was investigated and an instability threshold was found. Besides the investigation of multibunch instabilities, single-bunch instabilities are discussed. In addition, the acquisition unit of the digital feedback system can be triggered on external events. This was used to investigate the injection process and beam losses. It was shown that the transverse feedback system increases the injection efficiency. Another aspect of this thesis is the improvement of the signal quality of ultrashort coherent synchrotron radiation pulses, which are generated by the short-pulse facility at DELTA. The short-pulse facility is based

  14. Functional diversification of the RING finger and other binuclear treble clef domains in prokaryotes and the early evolution of the ubiquitin system.

    Burroughs, A Maxwell; Iyer, Lakshminarayan M; Aravind, L


    Recent studies point to a diverse assemblage of prokaryotic cognates of the eukaryotic ubiquitin (Ub) system. These systems span an entire spectrum, ranging from those catalyzing cofactor and amino acid biosynthesis, with only adenylating E1-like enzymes and ubiquitin-like proteins (Ubls), to those that are closer to eukaryotic systems by virtue of possessing E2 enzymes. Until recently E3 enzymes were unknown in such prokaryotic systems. Using contextual information from comparative genomics, we uncover a diverse group of RING finger E3s in prokaryotes that are likely to function with E1s, E2s, JAB domain peptidases and Ubls. These E1s, E2s and RING fingers suggest that features hitherto believed to be unique to eukaryotic versions of these proteins emerged progressively in such prokaryotic systems. These include the specific configuration of residues associated with oxyanion-hole formation in E2s and the C-terminal UFD in the E1 enzyme, which presents the E2 to its active site. Our study suggests for the first time that YukD-like Ubls might be conjugated by some of these systems in a manner similar to eukaryotic Ubls. We also show that prokaryotic RING fingers possess considerable functional diversity and that not all of them are involved in Ub-related functions. In eukaryotes, other than RING fingers, a number of distinct binuclear (chelating two Zn atoms) and mononuclear (chelating one zinc atom) treble clef domains are involved in Ub-related functions. Through detailed structural analysis we delineated the higher order relationships and interaction modes of binuclear treble clef domains. This indicated that the FYVE domain acquired the binuclear state independently of the other binuclear forms and that different treble clef domains have convergently acquired Ub-related functions independently of the RING finger. Among these, we uncover evidence for notable prokaryotic radiations of the ZF-UBP, B-box, AN1 and LIM clades of treble clef domains and present

  15. Prime rings with PI rings of constants

    Kharchenko, V K; Rodríguez-Romo, S


    It is shown that if the ring of constants of a restricted differential Lie algebra with a quasi-Frobenius inner part satisfies a polynomial identity (PI) then the original prime ring has a generalized polynomial identitiy (GPI). If additionally the ring of constants is semiprime then the original ring is PI. The case of a non-quasi-Frobenius inner part is also considered.

  16. Latitudinal gradients in tree ring stable carbon and oxygen isotopes reveal differential climate influences of the North American Monsoon System

    Szejner, Paul; Wright, William E.; Babst, Flurin; Belmecheri, Soumaya; Trouet, Valerie; Leavitt, Steven W.; Ehleringer, James R.; Monson, Russell K.


    The arrival of the North American Monsoon System (NAMS) terminates a presummer hyperarid period in the southwestern United States (U.S.), providing summer moisture that is favorable for forest growth. Montane forests in this region rely on winter snowpack to drive much of their growth; the extent to which they use NAMS moisture is uncertain. We addressed this by studying stable carbon and oxygen isotopes in earlywood and latewood from 11 sites along a latitudinal gradient extending from Arizona and New Mexico to Utah. This study provides the first regional perspective on the relative roles of winter versus summer precipitation as an ecophysiological resource. Here we present evidence that Ponderosa pine uses NAMS moisture differentially across this gradient. 13C/12C ratios suggest that photosynthetic water use efficiency during latewood formation is more sensitive to summer precipitation at the northern than at the southern sites. This is likely due to the fact that NAMS moisture provides sufficiently favorable conditions for tree photosynthesis and growth during most years in the southern sites, whereas the northern sites experience larger summer moisture variability, which in some years is limiting growth. Cellulose δ18O and δ13C values revealed that photoassimilates in the southern sites were produced under higher vapor pressure deficit conditions during spring compared to summer, demonstrating a previously underappreciated effect of seasonal differences in atmospheric humidity on tree ring isotope ratios. Our findings suggest that future changes in NAMS will potentially alter productivity and photosynthetic water use dynamics differentially along latitudinal gradients in southwestern U.S. montane forests.

  17. Towards a theory for the Uranian rings

    Goldreich, P.; Tremaine, S.


    Interparticle collisions, radiation drag, and differential precession all tend to disrupt the rings of Uranus. The first two effects lead to radial spreading which would disrupt a free ring in less than or approximately 100,000,000 yr. It is proposed that the rings are confined in radius by gravitational torques from a series of small satellites that orbit with the ring system. Differential precession tends to destroy the apse alignment of the elliptical epsilon ring. It is suggested that apse alignment is maintained by the self-gravity of the ring. The resulting mass of the epsilon ring is approximately 5 times 10 to the 18th power g. Its radial confinement requires (for example) a pair of satellites of mass approximately 10 to the 19th power g, in circular orbits roughly 500 km away on either side of the ring

  18. From the Icy Satellites to Small Moons and Rings: Spectral Indicators by Cassini-VIMS Unveil Compositional Trends in the Saturnian System

    Filacchione, G.; Capaccioni, F.; Ciarniello, M.; Nicholson, P. D.; Clark, R. N.; Cuzzi, J. N.; Buratti, B. B.; Cruikshank, D. P.; Brown, R. H.


    flat reflectance in the visible, making them remarkably different with respect to the other small moons. Moreover, we have observed that the two Tethys' lagrangian moons appear spectrally different, with Calypso characterized by more intense water ice bands than Telesto. Conversely, at visible wavelengths Polydeuces, Telesto and Methone are in absolute the more blue objects in the Saturn's system. The red slopes measured in the visible range on disk-integrated spectral data, showing varying degrees on all of the satellites, could be caused more by exogenic processes than by geologic and endogenic events which are operating on more localized scales. The principal exogenic processes active in the Saturn's system [11] which alter the satellites and rings surfaces are the E ring particles bombardment, the interaction with corotating plasma and energetic particles, the bombardment of exogenic dark material [12] and the water ice photolysis. A discussion about the correlations between these processes and the o bserved spectral classes is given. With the approaching of the Cassini "Gran Finale" orbits, VIMS will unveil with unprecedented spatial resolution the spectral properties of many small moons and rings. These data will be extremely valuable to improve our classification of the Saturn's satellites and rings.

  19. Synthetic studies on schisandra nortriterpenoids. Stereocontrolled synthesis of enantiopure C-5-epi ABC ring systems of micrandilactone A and lancifodilactone G using RCM.

    Maity, Soumitra; Matcha, Kiran; Ghosh, Subrata


    A stereocontrolled approach for the construction of ABC ring systems of micrandilactone A and lancifodilactone G has been developed. The synthesis involves construction of an enantiopure functionalized cycloheptene derivative 17 through RCM of the dienol 14 prepared from the known D-mannitol-derived unsaturated ester 12. A remarkable regioselectivity during hydroboration of the cycloheptene derivative 17 was observed during its transformation to the cycloheptanone 20. RCM of the diene 24 prepared stereoselectively from 20 gave the spiro-dihydrofuran 25. The ketal unit in 25 was then converted into the carbinols 28 and 36. A bromonium ion initiated highly stereocontrolled intramolecular etherification in 28 and 37 led to the tricyclic ethers 29 and 38, respectively. Reductive removal of bromine from 29 and 38 followed by RuO(4) oxidation led to the furo-furanone derivatives 31 and 40, the C-5-epi ABC ring systems of the schisandra nortriterpenoids 1 and 2.

  20. Asymmetric synthesis of a functionalized tricyclo[,6]decane ring system present in kelsoene and poduran

    Amrita Ghosh; Subrata Ghosh


    Synthesis of a functionalized tricyclo[,6]decane derivative in enantiomerically pure form, the core structure present in the natural products kelsoene and poduran, is described. The key steps involve a stereocontrolled copper (I)-catalyzed intramolecular [2+2] photocycloaddition of a 1, 6-diene prepared from D-mannitol to form a substituted bicyclo[3.2.0]heptane derivative and a ring closing olefin metathesis involving the vicinal substituents on the five-membered ring of the bicyclo[3.2.0]heptane derivative.

  1. A cavity ring-down spectroscopy system for high time resolution measurements of gaseous elemental mercury concentrations

    Pierce, Ashley M.

    The global cycling of mercury (Hg), a highly toxic environmental pollutant, currently has many unknowns. There are various sources of Hg to the atmosphere including both anthropogenic and natural sources. Processes involved in the global cycling of Hg include emissions from legacy Hg pools, deposition, re-emission, and chemical and physical transformation processes such as gas-phase oxidation and heterogeneous redox reactions. Gaseous elemental mercury (GEM) can represent >95% of Hg present in the atmosphere. GEM has a relatively long atmospheric lifetime, which allows it to be transported 1000s of km, effectively making it a global pollutant. Once deposited, Hg can be converted to methylmercury, a bioavailable form of Hg known to cause neurological damage in wildlife and humans. Current atmospheric Hg sensors require long analyzing periods for a single sample (minutes to hours), thus a faster-response sensor would improve characterization of surface-atmosphere exchange processes and atmospheric Hg dynamics. The goal of this thesis work was to develop a new, field-deployable sensor for high time resolution measurements of GEM in ambient air using pulsed cavity ring-down spectroscopy (CRDS). In this research, a CRDS system was developed using a pulsed laser (50 Hz pulse repetition rate) emitting wavelengths tunable between 215 and 280 nm (Hg absorbs at 253.65 nm), a high finesse 1-m-long cavity lined with two high reflectivity mirrors. Due to the long path length (˜1 km) produced inside the short cavity, sample volumes could be kept small while measurement sensitivity remained high. By optimizing the CRDS setup and reducing interferences (e.g., ozone concentration fluctuations), the current CRDS sensor was deployed in the field to measure GEM concentrations in ambient air. The sensor was also used for the first-ever GEM flux measurements by the eddy covariance flux method. Results showed that fast GEM fluctuations could be detected by the CRDS sensor and the

  2. Electronic voting systems for defending free will and resisting bribery and coercion based on ring anonymous signcryption scheme

    Tsung-Chih Hsiao


    Full Text Available Vote by ballot is the feature in a democratic society and the process of decision-making, tending to achieve the philosophy of democratic politics by having the public who are eligible to vote for competent candidates or leaders. With the rapid development of technologies and network applications, electronization has been actively promoted globally during the social transformation period that the concept of electronic voting is further derived. The major advantages of electronic voting, comparing with traditional voting, lie in the mobility strength of electronic voting, reducing a large amount of election costs and enhancing the convenience for the public. Electronic voting allows voters completing voting on the Internet that not only are climate and location restrictions overcome, but the voter turnout is also increased and the voting time is reduced for the public. With the development in the past three decades, electronic voting presents outstanding performance theoretically and practically. Nevertheless, it is regrettable that electronic voting schemes still cannot be completely open because of lures by money and threats. People to lure by money and threats would confirm the voters following their instructions through various methods that more factors would appear on election results, affecting the quality and fairness of the election. In this study, this project aims to design an electronic voting scheme which could actually defend voters’ free will so that lure of money and threats would fail. Furthermore, an electronic voting system based on Elliptic Curve Cryptography is proposed to ensure the efficiency and security, and Ring Signature and Signcryption are applied to reducing the computing costs. Moreover, this project also focuses on applying voting system to mobile devices. As the system efficiency and security are emphasized, voters do not need to participate in the election, but simply complete voting with smart phones, i

  3. Radical theory of rings

    Gardner, JW


    Radical Theory of Rings distills the most noteworthy present-day theoretical topics, gives a unified account of the classical structure theorems for rings, and deepens understanding of key aspects of ring theory via ring and radical constructions. Assimilating radical theory's evolution in the decades since the last major work on rings and radicals was published, the authors deal with some distinctive features of the radical theory of nonassociative rings, associative rings with involution, and near-rings. Written in clear algebraic terms by globally acknowledged authorities, the presentation

  4. Using Brillouin fiber-optic ring laser to provide base station with uplink optical carrier in a 10 GHz radio over fiber system

    CHEN Hao-shuo; LIN Ru-jian; YE Jia-jun


    In this paper, a 10 GHz radio over fiber system is analyzed. The Brillouin fiber-optic ring laser is used in the center station (CS) to suppress the optical carrier for the modulation depth enhancement. Simultaneously, the Stockes waveinduced by the Brillouin amplification injects and locks the Fabry-Perot (FP) laser to output a signal-mode optical source,which works as the uplink optical carrier.

  5. Recent Developments of Versatile Photoinitiating Systems for Cationic Ring Opening Polymerization Operating at Any Wavelengths and under Low Light Intensity Sources.

    Lalevée, Jacques; Mokbel, Haifaa; Fouassier, Jean-Pierre


    Photoinitiators (PI) or photoinitiating systems (PIS) usable in light induced cationic polymerization (CP) and free radical promoted cationic polymerization (FRPCP) reactions (more specifically for cationic ring opening polymerization (ROP)) together with the involved mechanisms are briefly reviewed. The recent developments of novel two- and three-component PISs for CP and FRPCP upon exposure to low intensity blue to red lights is emphasized in details. Examples of such reactions under various experimental conditions are provided.

  6. Broadband feedback systems for the damping of coherent beam instabilities in the stretcher ring ELSA; Breitbandige Feedback-Systeme zur Daempfung kohaerenter Strahlinstabilitaeten am Stretcherring ELSA

    Roth, Andre


    At the Electron Stretcher Facility ELSA an upgrade of the internal beam current up to 200 mA would be desirable in order to increase the intensity of the extracted electron beam for the future experimental hadron physics program. However, such an upgrade is mainly limited by the excitation of coherent beam instabilities in the stretcher ring. As active counteraction, broadband bunch-by-bunch feedback-systems for the longitudinal, as well as for both transverse planes were installed. After detection of the motion of each of the 27 4 stored bunches via beam position monitors, the systems determine independent correction signals for each bunch using digital signal processors. The amplified correction signals are applied to the beam by means of broadband longitudinal and transverse kicker structures. The detailed setup, the commissioning procedure and measurement results of the damping performance of the systems are presented. In addition, the operation of the longitudinal system during the fast energy ramp of 4 GeV/s from 1.2 GeV to 3.2 GeV is investigated.

  7. Evaluation of a relativistic electron ring system as a plasma target for buildup of compact-toroid configurations

    Condit, W.C.


    A review of the idea of using plasma-loaded electron rings as buildup targets for future compact-toroid machines is presented. Present experiments at Cornell University and Nagoya University are analyzed, and the need for auxiliary heating to reach interesting temperatures is described. Consideration of the effect of two-stream instability, toroidal field, and plasma containment are discussed.

  8. From Satellites to Rings: The Diversity of the Saturnian System Ices in the VIS-NIR at the End of Cassini-VIMS Nominal Mission

    Filacchione, Gianrico; Capaccioni, F.; Tosi, F.; Coradini, A.; Cerroni, P.; Clark, R. N.; Cuzzi, J. N.; Cruikshank, D. P.; Nicholson, P. D.; Hedman, M. M.; McCord, T. B.; Brown, R. H.; Buratti, B. J.; Jaumann, R.; Stephan, K.


    After four years of nominal mission, VIMS has observed the whole population of Saturnian icy objects allowing a comparative analysis of the VIS-NIR spectral properties of the regular satellites (Mimas, Enceladus, Tethys, Dione, Rhea, Hyperion, Iapetus, Phoebe), minor moons (Atlas, Prometheus, Pandora, Janus, Epimetheus, Telesto, Calypso) and main rings (A, B, C and Cassini division). The results we present are derived from the whole dataset available at june 2008 which consists of about 1500 full-disk observations of the moons as well as several radial mosaics of the ring system. The most important spectrophotometric indicators (I/F continua, VIS spectral slopes, water and carbon dioxide IR bands strengths and positions) are calculated for each observation in order to identify the disk-integrated compositional units of the satellites, the distribution of water ice respect to "contaminants” abundances and typical regolith grain properties for both satellites and rings. These quantities are varying between the almost pure water ice surfaces of Enceladus and Calypso to the organic and carbon dioxide rich Hyperion, Iapetus and Phoebe. Some significant differences are detected in the VIS colors of co-orbital moons Epimetheus and Janus, with the first very red and therefore similar to Hyperion while the last is more "neutral” these results could help to decipher the origins and evolutional story of these two moons. The water ice band strengths of the A-B rings are the most intense of the Saturnian system denoting a minimal presence of "contaminants” which can be estimated thanks to the 350-520 nm spectral slope. Finally we compare these spectral parameters with some TNOs and outer solar system objects (1995UG5, 90377-Sedna, 1996TO66, Pholus, Triton, Charon, Oberon, Titania) to search for possible analogies. This research was possible thanks to the support of the Italian Space Agency (ASI).

  9. Does the position of the electron-donating nitrogen atom in the ring system influence the efficiency of a dye-sensitized solar cell? A computational study.

    Biswas, Abul Kalam; Barik, Sunirmal; Das, Amitava; Ganguly, Bishwajit


    We have reported a number of new metal-free organic dyes (2-6) that have cyclic asymmetric benzotripyrrole derivatives as donor groups with peripheral nitrogen atoms in the ring, fluorine and thiophene groups as π-spacers, and a cyanoacrylic acid acceptor group. Density functional theory (DFT) and time-dependent DFT (TD-DFT) calculations were employed to examine the influence of the position of the donor nitrogen atom and π-conjugation on solar cell performance. The calculated electron-injection driving force (ΔG inject), electron-regeneration driving force (ΔG regen), light-harvesting efficiency (LHE), dipole moment (μ normal), and number of electrons transferred (∆q) indicate that dyes 3, 4, and 6 have significantly higher efficiencies than reference dye 1, which exhibits high efficiency. We also extended our comparison to some other reported dyes, 7-9, which have a donor nitrogen atom in the middle of the ring system. The computed results suggest that dye 6 possesses a higher incident photon to current conversion efficiency (IPCE) than reported dyes 7-9. Thus, the use of donor groups with peripheral nitrogen atoms appears to lead to more efficient dyes than those in which the nitrogen atom is present in the middle of the donor ring system. Graphical Abstract The locations of the nitrogen atoms in the donor groups in the designed dye molecules have an important influence on DSSC efficiency.

  10. Stirling engine piston ring

    Howarth, Roy B.


    A piston ring design for a Stirling engine wherein the contact pressure between the piston and the cylinder is maintained at a uniform level, independent of engine conditions through a balancing of the pressure exerted upon the ring's surface and thereby allowing the contact pressure on the ring to be predetermined through the use of a preloaded expander ring.

  11. Birth Control Ring

    ... Loss Surgery? A Week of Healthy Breakfasts Shyness Birth Control Ring KidsHealth > For Teens > Birth Control Ring A A A What's in this article? ... español Anillo vaginal anticonceptivo What Is It? The birth control ring is a soft, flexible, doughnut-shaped ring ...

  12. Actin Rings of Power.

    Schwayer, Cornelia; Sikora, Mateusz; Slováková, Jana; Kardos, Roland; Heisenberg, Carl-Philipp


    Circular or ring-like actin structures play important roles in various developmental and physiological processes. Commonly, these rings are composed of actin filaments and myosin motors (actomyosin) that, upon activation, trigger ring constriction. Actomyosin ring constriction, in turn, has been implicated in key cellular processes ranging from cytokinesis to wound closure. Non-constricting actin ring-like structures also form at cell-cell contacts, where they exert a stabilizing function. Here, we review recent studies on the formation and function of actin ring-like structures in various morphogenetic processes, shedding light on how those different rings have been adapted to fulfill their specific roles.

  13. Alternative loop rings

    Goodaire, EG; Polcino Milies, C


    For the past ten years, alternative loop rings have intrigued mathematicians from a wide cross-section of modern algebra. As a consequence, the theory of alternative loop rings has grown tremendously. One of the main developments is the complete characterization of loops which have an alternative but not associative, loop ring. Furthermore, there is a very close relationship between the algebraic structures of loop rings and of group rings over 2-groups. Another major topic of research is the study of the unit loop of the integral loop ring. Here the interaction between loop rings and group ri

  14. Automatic Control Technology for High Precision Multi-Ring Assembly System%高精度多环片自动装配控制技术

    王晓东; 单镇东; 罗怡; 李聪明


    In order to realize automatic assembly for the ring parts , a high precision multi-ring automatic assembly system was designed and set up .The main frame of the system , including 4 guided shafts and 4 linear bearings , ensures the guided accuracy and rigidity .The linear guide assembly can switch assembly operation to assemble and remove rings automatically .In the assembly direction , spiral elevator and grat-ing achieve position accuracy of the rings .In the LabVIEW environment , layered software architecture and modular control strategy avoid unnecessary repeated data detection and lost , thus meeting the assem-bly precision of ring components .Control system consisting of system initialization module , parameter set-ting module , assembly module and pulling-out module was programmed .The automatic assembly task was fulfilled by communication and collaboration between these modules .Experimental results show that the maximum position error was 26μm and the perpendicularity error was 17μm.The average assembly time for one individual ring was 75 s.The assembly system can satisfy the requirements of ring component assembly .%为了实现对微小环片零件的自动化装配,搭建了自动装配系统。通过4根直线导向轴与4个直线轴承来提高系统的导向精度和刚度。采用直线导轨进行各装配作业模块之间的切换,保证了微小环片零件的自动装配与取出。在环片的装配方向上,螺旋升降机和光栅尺实现环片的位置精度控制。在LabVIEW编程环境中,采用分层软件架构和模块化控制思想,避免了不必要的数据循环检测与丢失,能够达到环片组件的装配精度要求。控制系统分为系统初始化模块、参数设置模块、装配模块和取出模块,自动装配系统通过各个模块间的相互交流配合完成装配任务。采用本文中自动装配系统装配环片的实验结果表明,环片零件装配的最大位置误差为26

  15. A proposed direct measurement of cross section at Gamow window for key reaction $^{19}$F($p$,$\\alpha$)$^{16}$O in Asymptotic Giant Branch stars with a planned accelerator in CJPL

    He, J J; Ma, S B; Hu, J; Zhang, L Y; Fu, C B; Zhang, N T; Lian, G; Su, J; Li, Y J; Yan, S Q; Shen, Y P; Hou, S Q; Jia, B L; Zhang, T; Zhang, X P; Guo, B; Kubono, S; Liu, W P


    In 2014, the National Natural Science Foundation of China (NSFC) approved the Jinping Underground Nuclear Astrophysics laboratory (JUNA) project, which aims at direct cross-section measurements of four key stellar nuclear reactions right down to the Gamow windows. In order to solve the observed fluorine overabundances in Asymptotic Giant Branch (AGB) stars, measuring the key $^{19}$F($p$,$\\alpha$)$^{16}$O reaction at effective burning energies (i.e., at Gamow window) is established as one of the scientific research sub-projects. The present paper describes this sub-project in details, including motivation, status, experimental setup, yield and background estimation, aboveground test, as well as other relevant reactions.

  16. Estimation of the operational reliability determined with Weibull modulus based on the abrasive wear in a cylinder-piston ring system

    J. Piątkowski


    Full Text Available Purpose: The main purpose of the study was to determine methodology for estimation of the operational reliability based on the statistical results of abrasive wear testing.Design/methodology/approach: For research, a traditional tribological system, i.e. a friction pair of the AlSi17CuNiMg silumin in contact with the spheroidal graphite cast iron of EN-GJN-200 grade, was chosen. Conditions of dry friction were assumed. This system was chosen based on mechanical cooperation between the cylinder (silumin and piston rings (spheroidal graphite cast iron in conventional internal combustion piston engines with spark ignition.Findings: Using material parameters of the cylinder and piston rings, nominal losses qualifying the cylinder for repair and the maximum weight losses that can be smothered were determined. Based on the theoretical number of engine revolutions to repair and stress acting on the cylinder bearing surface, the maximum distance that the motor vehicle can travel before the seizure of the cylinder occurs was calculated. These results were the basis for statistical analysis carried out with the Weibull modulus, the end result of which was the estimation of material reliability (the survival probability of tribological system and the determination of a pre-operation warranty period of the tribological system.Research limitations/implications: The analysis of Weibull distribution modulus will estimate the reliability of a tribological cylinder-ring system enabled the determination of an approximate theoretical time of the combustion engine failure-free running.Originality/value: The results are valuable statistical data and methodology proposed in this paper can be used to determine a theoretical life time of the combustion engine.

  17. UV-laser microdissection system - A novel approach for the preparation of high-resolution stable isotope records (δ13C/δ18O) from tree rings

    Schollaen, Karina; Helle, Gerhard


    Intra-annual stable isotope (δ13C and δ18O) studies of tree rings at various incremental resolutions have been attempting to extract valuable seasonal climatic and environmental information or assessing plant ecophysiological processes. For preparing high-resolution isotope samples normally wood segments or cores are mechanically divided in radial direction or cut in tangential direction. After mechanical dissection, wood samples are ground to a fine powder and either cellulose is extracted or bulk wood samples are analyzed. Here, we present a novel approach for the preparation of high-resolution stable isotope records from tree rings using an UV-laser microdissection system. Firstly, tree-ring cellulose is directly extracted from wholewood cross-sections largely leaving the wood anatomical structure intact and saving time as compared to the classical procedure. Secondly, micro-samples from cellulose cross-sections are dissected with an UV-Laser dissection microscope. Tissues of interest from cellulose cross-sections are identified and marked precisely with a screen-pen and dissected via an UV-laser beam. Dissected cellulose segments were automatically collected in capsules and are prepared for stable isotope (δ13C and δ18O) analysis. The new techniques facilitate inter- and intra-annual isotope analysis on tree-ring and open various possibilities for comparisons with wood anatomy in plant eco-physiological studies. We describe the design and the handling of this novel methodology and discuss advantages and constraints given by the example of intra-annual oxygen isotope analysis on tropical trees.

  18. Automatic repair system design of ring-die hole%环模模孔自动修复系统设计

    刘星; 徐翠锋; 郭庆


    环模在饲料加工机械中是一个易阻塞的核心部件。针对国内外普遍的人工手动清理、自动化效率低、劳动强度大、易损坏环模等一系列不足,借用磁敏元件检测管道漏磁的设计思想,采用霍尔传感器探测饲料环模模孔方式,根据捕获模孔的信号特征,基于高效的黄金分割最优化搜索法研制了能准确捕获模孔的信号特征、孔心定位误差不超过0.2 mm、模孔修复效率高、钻头刮伤模孔比率为1.12%及良好的兼容和扩展能力等特点的软硬件一体化的专用环模修复平台。平台以AVR(AT‐mega128L )处理器为核心,搭载小型μC/OS‐II操作系统,完善的功能按键和LCD建立良好的人机交互平台,构建了完整的嵌入式工控机系统。%Ring mold is an easily blocked core component in feed processing machinery .To a series of general deficiencies just like cleanup manually ,inefficient automation ,labor‐intensive and easily brittle both at home and abroad ,this article describes a dedicated ring mold repair platform integrated with hardware and software based on MFL design ideas by using magnetic element and using Hall sensors to detect ,analog signal characteristics of ring mold hole and the efficient optimized search algorithm of the golden section .This device has possessed a number of advantages .For example ,it could develop to accurately estimate ring mold hole .It has high ring mold hole repair efficiency .The position error of whole center is less than 0 .2 mm and the scratch ratio of drill hole is about 1 .12% .Start with AVR (ATmega128L) processor as the core component ,carrying a small μC/OS‐II operating system ,improving function buttons and LCD .It establishes a good interactive platform and constitutes complete embedded computer systems .

  19. On JB-Rings

    Huanyin CHEN


    A ring R is a QB-ring provided that aR + bR = R with a, b ∈ R implies that there exists a y ∈ R such that a+by ∈ R-1q. It is said that a ring R is a JB-ring provided that R/J(R) is a QB-ring, where J(R) is the Jacobson radical of R. In this paper, various necessary and sufficient conditions, under which a ring is a JB-ring, are established. It is proved that JB-rings can be characterized by pseudo-similarity. Furthermore, the author proves that R is a J B-ring iff so is R/J(R)2.

  20. RING E3 ligases

    Cho, Seok Keun; Ryu, Moon Young; Kim, Jong Hum


    response pathways of plants through various molecular and genetic studies. In particular, it was recently discovered that ubiquitin proteasome system (UPS), a regulatory mechanism for protein turn over, is greatly involved in the stress responsive pathways. In the UPS, many E3 ligases play key roles...... in recognizing and tethering poly-ubiquitins on target proteins for subsequent degradation by the 26S proteasome. Here we discuss the roles of RING ligases that have been defined in related to abiotic stress responses in plants....

  1. History of Neptune's Ring Arcs

    Esposito, L. W.; Colwell, J. E.; Canup, R. M.


    The recent dynamical calculations for Neptune's Adams ring arcs by Foryta and Sicardy (1996) and Hanninen and Porco (1997) determine the basic evolutionary parameters for this system. The ring evolution is dominated by stochastic events, particularly chaotic motion that causes a migration between the corotation sites (FS96) and collisions near quadrature (HP97). A basic problem is that the high velocity collisions that produce the dusty arcs at the Galatea corotation resonances rapidly depopulate these sites (Colwell and Esposito 1990). With the new results in hand for the evolution of the ring particles over periods of less than a century, we can now calculate the long-term stochastic evolution of the Adams ring. Using a finite Markov chain as a model for this stochastic process, we follow the suggestion by FS96 that corotation sites provide preferential locations for accretion. A more general conclusion is that the longitudinal concentration of material in a few nearby sites (and that the majority of the Adams ring material is residing there) requires either an exceedingly recent event (EC92) or that the corotation sites be absorbing states of the Markov chain.In the latter case, the competing processes of chaotic diffusion and frustrated accretion can provide the arc and clump features as recurrent transient events near the Roche limit. Similar phenomena would be expected for Saturn's F and G rings.

  2. On semi ring bornologies

    Imran, A. N.; Rakhimov, I. S.; Husain, Sh. K. Said


    Our main focus in this work is to introduce new structure bornological semi rings. This generalizes the theory of algebraic semi rings from the algebraic setting to the framework of bornological sets. We give basic properties for this new structure. As well as, We study the fundamental construction of bornological semi ring as product, inductive limits and projective limits and their extensions on bornological semi ring. Additionally, we introduce the category of bornological semi rings and study product and pullback (fiber product) in the category of bornological semi rings.

  3. Investigation of fluorine in SiO2 and on Si surface by the 19F(p,αγ)16O reaction, secondary-ion mass spectrometry, and x-ray photoelectron spectroscopy

    Yu, Byoung-gon; Arai, Eiichi; Nishioka, Yasushiro; Ohji, Yuzuru; Iwata, Seiichi; Ma, T. P.


    A fluorinated thermal SiO2, grown after HF surface treatment without de-ionized water rinse, was estimated to contain ˜3×1013 cm-2 of fluorine by the 19F(p,αγ)16O reaction. Secondary-ion mass spectrometry data indicate that the SiF distribution is peaked at the SiO2/Si interface in the fluorinated oxide. The time-dependent change of the absolute amount of fluorine on the HF-treated silicon surface as a function of storage time in air or in vacuum was also investigated by the 19F(p,αγ)16O reaction. The initial number of fluorine atoms on the HF-treated silicon surface was estimated to be ˜1015 cm-2 before substantial desorption took place. Fluorine atoms desorb from the silicon surface much more rapidly if the sample is stored in air than in vacuum. These results were also supported by the x-ray photoelectron spectroscopy measurement.

  4. The Pulsed Power Converter and Septum Magnet System for Injection into the Electron Storage Ring at ESRF

    Perrine, J P; Völker, F V


    At ESRF, the European Synchrotron Radiation Facility in Grenoble, electrons are accelerated, via a 200 MeV Linac and a 6 GeV synchrotron booster, and injected into the storage ring at 10 Hz rate. Two thin septum blade magnets and an eddy current sheet type septum magnet provide the final deflection of the injected beam. The operational requirements of the e- injection scheme and the resulting demanding hardware specifications are recalled. The pulsed septum magnets are briefly described. The design, circuit layout and construction of the power converters are related with emphasis on innovative aspects of general interest. Results of tests during commissioning are reported.

  5. On the appearance of a system of ring vortices in the mixing layer of axially symmetric turbulent jets under acoustic action

    Pimshtein, V. G.


    The shadow visualization method is applied to study the process of loss of stability of the mixing layer of a subsonic axially symmetric turbulent jet under longitudinal internal action of saw-tooth sound waves of finite amplitude. Such action leads to the formation of a system of ring vortices in the mixing layer at the frequency of its intrinsic instability. The interaction of the vortices can be accompanied by sound emission. A similar phenomenon is also observed in turbulent jets for small supercritical pressure fluctuations on a nozzle.

  6. Intrinsic structure in Saturn's rings

    Albers, N.


    Saturn's rings are the most prominent in our Solar system and one example of granular matter in space. Dominated by tides and inelastic collisions the system is highly flattened being almost 300000km wide while only tens of meters thick. Individual particles are composed of primarily water ice and range from microns to few tens of meters in size. Apparent patterns comprise ringlets, gaps, kinematic wakes, propellers, bending waves, and the winding spiral arms of density waves. These large-scale structures are perturbations foremost created by external as well as embedded moons. Observations made by the Cassini spacecraft currently in orbit around Saturn show these structures in unprecedented detail. But high-resolution measurements reveal the presence of small-scale structures throughout the system. These include self-gravity wakes (50-100m), overstable waves (100-300m), subkm structure at the A and B ring edges, "straw" and "ropy" structures (1-3km), and the C ring "ghosts". Most of these had not been anticipated and are found in perturbed regions, driven by resonances with external moons, where the system undergoes periodic phases of compression and relaxation that correlate with the presence of structure. High velocity dispersion and the presence of large clumps imply structure formation on time scales as short as one orbit (about 10 hours). The presence of these intrinsic structures is seemingly the response to varying local conditions such as internal density, optical depth, underlying particle size distribution, granular temperature, and distance from the central planet. Their abundance provides evidence for an active and dynamic ring system where aggregation and fragmentation are ongoing on orbital timescales. Thus a kinetic description of the rings may be more appropriate than the fluid one. I will present Cassini Ultraviolet Spectrometer (UVIS) High Speed Photometer (HSP) occultations, Voyager 1 and 2 Imaging Science Subsystem (ISS), and high

  7. Cooperative robustness to static disorder: Superradiance and localization in a nanoscale ring to model light-harvesting systems found in nature

    Celardo, G. Luca; Giusteri, Giulio G.; Borgonovi, Fausto


    We analyze a one-dimensional ring structure composed of many two-level systems, in the limit where only one excitation is present. The two-level systems are coupled to a common environment, where the excitation can be lost, which induces super- and subradiant behavior, an example of cooperative quantum coherent effect. We consider time-independent random fluctuations of the excitation energies. This static disorder, also called inhomogeneous broadening in literature, induces Anderson localization and is able to quench superradiance. We identify two different regimes: (i) weak opening, in which superradiance is quenched at the same critical disorder at which the states of the closed system localize; (ii) strong opening, with a critical disorder strength proportional to both the system size and the degree of opening, displaying robustness of cooperativity to disorder. Relevance to photosynthetic complexes is discussed.

  8. Interactive Visualization of Shadow Effects in the Planetary System of Saturn, its Rings and its Moons using an OpenGL Shader in IDL

    Fajardo Hernandez, E. M.; Pomarède, D.


    The planetary system of Saturn, its rings and its moons is a fantastic playground where physicists are confronting theories and observations. Since its insertion into orbit in 2004, the Cassini-Huygens spacecraft has returned a wealth of high-resolution images and data that calls for the development of dedicated interactive, immersive, three-dimensional, multi-purpose analysis and visualization tools. Alongside with observations, numerical simulations also provide new insights into the fundamental processes at stake in the formation of this system. The SDvision graphical interface, developed in the context of IDL Object Graphics and intended primarily for the visualization of complex and massive astrophysical plasma simulations, has been extended to provide an interactive visualization of both numerical simulations and observations of Saturn, its rings, and its moons. One major missing feature of IDL Object Graphics is the ability to render shadow effects at all. We have overcome this limitation by developing a custom GLSL Shader that is invoked by IDL objects. This Shader, based on purely geometrical computations, is fast and allows for seamless exploratory visualization of the planetary system.

  9. The ultrastructure of the anterior end of male Onchocerca volvulus: papillae, amphids, nerve ring and first indication of an excretory system in the adult filarial worm.

    Strote, G; Bonow, I; Attah, S


    A detailed morphological investigation of the anterior sensory organs, the nerve ring and a glomerulus-like structure in male Onchocerca volvulus was performed by means of electron microscopy. The 8 head papillae are arranged in the common 4 + 4 pattern of most filarial worms in circles around the mouth opening. The amphidial openings are found between the circles of inner and outer papillae on both sides of the mouth. Inside, several additional nerve axons are seen in the tissue of the anterior tip not related to one of the identified papillar structures. The inner and outer papillae exhibit a remarkably different fine structure, and are part of a complex system of at least 2 different receptor cell types at the anterior tip of the worm. The amphidial channel contains 8 modified cilia; accessory axons are associated with the cytoplasm of the sheath cell. The anterior nerve ring of male worms is located about 150 micrometers posterior from the outermost tip of the head region. It consists of several fibres coiled around the oesophagus. The comparison of the fine structure of the central nervous system did not show the expected morphological differences associated with the heterogeneous age distribution in the natural worm population. This was in contrast to previous findings with respect to tissues in different parts of the worm. The study also provides the first evidence that suggests the existence of an excretory organ in a filarial worm in the region of the anterior nerve ring. Paired glomerulus-like structures in the lateral chords and a canal formed by a projection of the basal zone of the cuticles were identified.

  10. Groups, rings, modules

    Auslander, Maurice


    This classic monograph is geared toward advanced undergraduates and graduate students. The treatment presupposes some familiarity with sets, groups, rings, and vector spaces. The four-part approach begins with examinations of sets and maps, monoids and groups, categories, and rings. The second part explores unique factorization domains, general module theory, semisimple rings and modules, and Artinian rings. Part three's topics include localization and tensor products, principal ideal domains, and applications of fundamental theorem. The fourth and final part covers algebraic field extensions

  11. Birth Control Ring

    ... Right Sport for You Healthy School Lunch Planner Birth Control Ring KidsHealth > For Teens > Birth Control Ring Print A A A What's in ... español Anillo vaginal anticonceptivo What Is It? The birth control ring is a soft, flexible, doughnut-shaped ...

  12. On Weakly Semicommutative Rings*



    A ring R is said to be weakly scmicommutative if for any a, b ∈ R,ab = 0 implies aRb C_ Nil(R), where Nil(R) is the set of all nilpotcnt elements in R.In this note, we clarify the relationship between weakly semicommutative rings and NI-rings by proving that the notion of a weakly semicommutative ring is a proper generalization of NI-rings. We say that a ring R is weakly 2-primal if the set of nilpotent elements in R coincides with its Levitzki radical, and prove that if R is a weakly 2-primal ring which satisfies oα-condition for an endomorphism α of R (that is, ab = 0 (←→) aα(b) = 0 where a, b ∈ R) then the skew polynomial ring R[π; αα]is a weakly 2-primal ring, and that if R is a ring and I is an ideal of R such that I and R/I are both weakly semicommutative then R is weakly semicommutative.Those extend the main results of Liang et al. 2007 (Taiwanese J. Math., 11(5)(2007),1359-1368) considerably. Moreover, several new results about weakly semicommutative rings and NI-rings are included.


    Christian, G B; Bett, D R; Burrows, P N; Davis, M R; Gerbershagen, A; Perry, C; Constance, B; Resta-Lopez, J


    An FPGA-based monitoring system has been developed to study multi-bunch beam instabilities in the damping ring (DR) of the KEK Accelerator Test Facility (ATF), utilising a stripline beam position monitor (BPM) and existing BPM processor hardware. The system is designed to record the horizontal and/or vertical positions of up to three bunches in the DR in single-bunch multi-train mode or the head bunch of up to three trains in multi-bunch mode, with a bunch spacing of 5.6 ns. The FPGA firmware and data acquisition software were modified to record turn-by-turn data for up to six channels and 1–3 bunches in the DR. An overview of the system and initial results will be presented.

  14. Combined Brillouin light scattering and microwave absorption study of magnon-photon coupling in a split-ring resonator/YIG film system

    Klingler, S., E-mail:; Maier-Flaig, H.; Weiler, M. [Walther-Meißner-Institut, Bayerische Akademie der Wissenschaften, Walther-Meißner-Straße 8, 85748 Garching (Germany); Physik-Department, Technische Universität München, 85748 Garching (Germany); Gross, R.; Huebl, H.; Goennenwein, S. T. B. [Walther-Meißner-Institut, Bayerische Akademie der Wissenschaften, Walther-Meißner-Straße 8, 85748 Garching (Germany); Physik-Department, Technische Universität München, 85748 Garching (Germany); Nanosystems Initiative Munich (NIM), 80799 Munich (Germany); Hu, C.-M. [Department of Physics and Astronomy, University of Manitoba, Winnipeg, Manitoba R3T2N2 (Canada)


    Microfocused Brillouin light scattering (BLS) and microwave absorption (MA) are used to study magnon-photon coupling in a system consisting of a split-ring microwave resonator and an yttrium iron garnet (YIG) film. The split-ring resonator is defined by optical lithography and loaded with a 1 μm-thick YIG film grown by liquid phase epitaxy. BLS and MA spectra of the hybrid system are simultaneously recorded as a function of the applied magnetic field magnitude and microwave excitation frequency. Strong coupling of the magnon and microwave resonator modes is found with a coupling strength of g{sub eff} /2π = 63 MHz. The combined BLS and MA data allow us to study the continuous transition of the hybridized modes from a purely magnonic to a purely photonic mode by varying the applied magnetic field and microwave frequency. Furthermore, the BLS data represent an up-conversion of the microwave frequency coupling to optical frequencies.

  15. Synthesis, characterization and catalytic activity of Ag-acidfuchsin nanohybrid system towards the ring opening polymerization of ε-caprolactone.

    Meenarathi, B; Palanikumar, S; Kannammal, L; Anbarasan, R


    The acidfuchsin (AF) decorated Ag nanoparticle (NP) was synthesized and its ability towards the ring opening polymerization (ROP) of ε-caprolactone (CL) was studied under N2 atmosphere at 160 °C in the presence of stannous octoate (SO) as a catalyst. Both the nanohybrid and nanocomposites were characterized by various analytical tools like Fourier transform infrared (FTIR) spectroscopy, UV-visible spectroscopy, nuclear magnetic resonance (NMR) spectroscopy, fluorescence spectroscopy, gel permeation chromatography (GPC), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS). The number of binding site from the fluorescence spectrum confirmed that all the functional groups present in AF might have been involved in the ROP of CL. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Physics of quantum rings

    Fomin, Vladimir M


    This book deals with a new class of materials, quantum rings. Innovative recent advances in experimental and theoretical physics of quantum rings are based on the most advanced state-of-the-art fabrication and characterization techniques as well as theoretical methods. The experimental efforts allow to obtain a new class of semiconductor quantum rings formed by capping self-organized quantum dots grown by molecular beam epitaxy. Novel optical and magnetic properties of quantum rings are associated with non-trivial topologies at the nanoscale. An adequate characterization of quantum rings is po

  17. Envelopes of Commutative Rings

    Rafael PARRA; Manuel SAOR(I)N


    Given a significative class F of commutative rings,we study the precise conditions under which a commutative ring R has an F-envelope.A full answer is obtained when.F is the class of fields,semisimple commutative rings or integral domains.When F is the class of Noetherian rings,we give a full answer when the Krull dimension of R is zero and when the envelope is required to be epimorphic.The general problem is reduced to identifying the class of non-Noetherian rings having a monomorphic Noetherian envelope,which we conjecture is the empty class.



    Proxy signatures have been used to enable the transfer of digital signing power within some context and ring signatures can be used to provide the anonymity of a signer. By combining the functionalities of proxy signatures and ring signatures, this paper introduces a new concept, named ring proxy signature, which is a proxy signature generated by an anonymous member from a set of potential signers. The paper also constructs the first concrete ring proxy signature scheme based on the provably secure Schnorr's signatures and two ID-based ring proxy signature schemes. The security analysis is provided as well.

  19. An explanation for Neptune's ring arcs

    Porco, Carolyn C.


    The Voyager mission revealed a complex system of rings and ring arcs around Neptune and uncovered six new satellites, four of which occupy orbits well inside the ring region. Analysis of Voyager data shows that a radial distortion with an amplitude of approximately 30 kilometers is traveling through the ring arcs, a perturbation attributable to the nearby satellite Galatea. Moreover, the arcs appear to be azimuthally confined by a resonant interaction with the same satellite, yielding a maximum spread in ring particle semimajor axes of 0.6 kilometer and a spread in forced eccentricities large enough to explain the arc's 15-kilometer radial widths. Additional ring arcs discovered in the course of this study give further support to this model.

  20. The contraceptive vaginal ring.

    Edwardson, Jill; Jamshidi, Roxanne


    The contraceptive vaginal ring offers effective contraception that is self-administered, requires less frequent dosing than many other forms of contraception, and provides low doses of hormones. NuvaRing (Organon, Oss, The Netherlands), the only contraceptive vaginal ring approved for use in the United States, contains etonogestrel and ethinyl estradiol. It is inserted into the vagina for 3 weeks, followed by a 1-week ring-free period, and works by inhibiting ovulation. Most women note a beneficial effect on bleeding profiles and are satisfied with NuvaRing. Commonly reported adverse events include vaginitis, leukorrhea, headaches, and device-related events such as discomfort. Serious adverse events are rare. In Chile and Peru, progesterone-only vaginal contraceptive rings are available for nursing women. Studies are ongoing examining new formulations of vaginal contraceptive rings.

  1. New Dust Belts of Uranus: One Ring, Two Ring, Red Ring, Blue Ring

    de Pater, I; Hammel, H B; Gibbard, S G; Showalter, M R


    We compare near-infrared observations of the recently discovered outer rings of Uranus with HST results. We find that the inner ring, R/2003 U 2, is red, whereas the outer ring, R/2003 U 1, is very blue. Blue is an unusual color for rings; Saturn's enigmatic E ring is the only other known example. By analogy to the E ring, R/2003 U 1 is probably produced via impacts into the embedded moon Mab, which apparently orbits at a location where non-gravitational perturbations favor the survival and spreading of sub-micron sized dust. R/2003 U 2 more closely resembles Saturn's G ring.

  2. Simulation of Rings about Ellipsoidal Bodies

    Gupta, Akash; Nadkarni-Ghosh, Sharvari; Sharma, Ishan


    Recent discovery of rings around Chariklo, a centaur orbiting the Sun (F. Braga-Ribas et al., 2014) and speculations of rings around minor planet, Chiron (Ortiz et al., 2015), Saturn's satellites, Rhea (Jones et al., 2008; Schenk et al., 2011), Iapetus (Ip, 2006) or exoplanets, suggest that rings about non-spherical bodies is perhaps a more general phenomenon than anticipated. As a first step towards understanding such systems, we examine the dynamical behavior of rings around similar bodies using N-body simulations. Our code employs the `local simulation method' (Wisdom & Tremaine, 1988; Salo, 1995) and accounts for particle interactions via collisions using Discrete Element Method (Cundall & Strack, 1978; Bhateja et al., 2016) and mutual gravitation. The central body has been modeled as an axisymmetric ellipsoid characterized by its axis ratio, or defined via characteristic frequencies (circular, vertical and epicyclic frequency) representing the gravitational field of an axisymmetric body. We vary the central body's characterizing parameter and observe the change in various ring properties like the granular temperature, impact frequency, radial width and vertical thickness. We also look into the effect on ring properties upon variation in the size of the central body-ring system. Further, we investigate the role of characteristic frequencies in dictating the ring dynamics, and how this could help in qualitatively estimating the ring dynamics about any arbitrary central body with symmetry about the equatorial plane and the axis normal to it.

  3. Certain near-rings are rings, II

    Howard E. Bell


    Full Text Available We investigate distributively-generated near-rings R which satisfy one of the following conditions: (i for each x,y∈R, there exist positive integers m, n for which xy=ymxn; (ii for each x,y∈R, there exists a positive integer n such that xy=(yxn. Under appropriate additional hypotheses, we prove that R must be a commutative ring.

  4. Accretion in Saturn's F Ring

    Meinke, B. K.; Esposito, L. W.; Stewart, G.


    Saturn's F ring is the solar system's principal natural laboratory for direct observation of accretion and disruption processes. The ring resides in the Roche zone, where tidal disruption competes with self-gravity, which allows us to observe the lifecycle of moonlets. Just as nearby moons create structure at the B ring edge (Esposito et al. 2012) and the Keeler gap (Murray 2007), the F ring "shepherding" moons Prometheus and Pandora stir up ring material and create observably changing structures on timescales of days to decades. In fact, Beurle et al (2010) show that Prometheus makes it possible for "distended, yet gravitationally coherent clumps" to form in the F ring, and Barbara and Esposito (2002) predicted a population of ~1 km bodies in the ring. In addition to the observations over the last three decades, the Cassini Ultraviolet Imaging Spectrograph (UVIS) has detected 27 statistically significant features in 101 occultations by Saturn's F ring since July 2004. Seventeen of those 27 features are associated with clumps of ring material. Two features are opaque in occultation, which makes them candidates for solid objects, which we refer to as Moonlets. The 15 other features partially block stellar signal for 22 m to just over 3.7 km along the radial expanse of the occultation. Upon visual inspection of the occultation profile, these features resemble Icicles, thus we will refer to them as such here. The density enhancements responsible for such signal attenuations are likely due to transient clumping of material, evidence that aggregations of material are ubiquitous in the F ring. Our lengthy observing campaign reveals that Icicles are likely transient clumps, while Moonlets are possible solid objects. Optical depth is an indicator of clumping because more-densely aggregated material blocks more light; therefore, it is natural to imagine moonlets as later evolutionary stage of icicle, when looser clumps of material compact to form a feature that appears

  5. Cross sections for proton induced high energy γ -ray emission (PIGE) in reaction 19 F(p, αγ)16 O at incident proton energies between 1.5 and 4 MeV

    Cabanelas, P.; Cruz, J.; Fonseca, M.; Henriques, A.; Lourenço, F.; Luís, H.; Machado, J.; Pires Ribeiro, J.; Sánchez-Benítez, A. M.; Teubig, P.; Velho, P.; Zarza-Moreno, M.; Galaviz, D.; Jesus, A. P.


    We have studied the high energy gamma-rays produced in the reaction 19 F(p, αγ)16 O for incident proton energies from 1.5 to 4.0 MeV over NaF/Ag and CaF2/Ag thin targets in two different sets of data. Gamma-rays were detected with a High Purity Ge detector with an angle of 130° with respect to the beam axis. The cross-sections for the high energy gamma-rays of 6.129, 6.915 and 7.115 MeV have been measured for the whole group between 5 and 7.2 MeV with accuracy better than 10%. A new energy range was covered and more points are included in the cross-sections data base expanding the existing set of data. Results are in agreement with previous measurements in similar conditions.

  6. Cross Sections for proton induced high energy $\\gamma$-ray emission (PIGE) in reaction $^{19}$F(p,$\\alpha\\gamma$)$^{16}$O at incident proton energies between 1.5 and 4 MeV

    Cabanelas, P; Fonseca, M; Galaviz, D; Henriques, A; Jesus, A P; Luís, H; Sánchez-Benítez, A; Santos, C; Silva, H; Teubig, P; Velho, P


    We have studied the high energy gamma-rays produced in the reaction $^{19}$F(p,$\\alpha\\gamma$)$^{16}$O for incident proton energies from 1.5 to 4.0 MeV over NaF/Ag and CaF$_2$/Ag thin targets in two different sets of data. Gamma-rays were detected with a High Purity Ge detector with an angle of 130$^{o}$ with respect to the beam axis. The cross-sections for the high energy gamma-rays of 6.129, 6.915 and 7.115 MeV have been measured for the whole group between 5 and 7.2 MeV with accuracy better than 10%. A new energy range was covered and more points are included in the cross-sections data base. Results are in agreement with previous measurements in similar conditions.

  7. Dream of Isochronous Ring Again

    Hama, H


    More than 20 years ago, D.A.G. Deacon proposed an isochronous storage ring for FEL to avoid bunch heating and decreasing instantaneous gain [1]. Some of low momentum compaction (alpha) operations have been carried out, and recently coherent infrared radiation are observed on a 3rd generation light source. Because the 3rd generation rings are optimized to obtain very low emittance beam, the dispersion function in the arc sections are much reduced by introducing large bending radius, so that those are very big machines. Meanwhile N.A. Vinokurov et al. recently proposed a ring type SASE FEL based on a complete isochronous bending transport [2]. At least, experimental and theoretical study of the isochronous ring so far suggests nonlinear effects resulted from higher order dispersion and chromaticity declines the "complete" isochronous system. On the other hand, in a wavelength region of THz, tolerance of the path length along a turn of the ring seems to be within our reach. A concept to preserve of a form factor...

  8. Efficient Diethylzinc/Gallic Acid and Diethylzinc/Gallic Acid Ester Catalytic Systems for the Ring-Opening Polymerization of rac-Lactide

    Karolina Żółtowska


    Full Text Available Polylactide (PLA represents one of the most promising biomedical polymers due to its biodegradability, bioresorbability and good biocompatibility. This work highlights the synthesis and characterization of PLAs using novel diethylzinc/gallic acid (ZnEt2/GAc and diethylzinc/propyl gallate (ZnEt2/PGAc catalytic systems that are safe for human body. The results of the ring-opening polymerization (ROP of rac-lactide (rac-LA in the presence of zinc-based catalytic systems have shown that, depending on the reaction conditions, “predominantly isotactic”, disyndiotactic or atactic PLA can be obtained. Therefore, the controlled and stereoselective ROP of rac-LA is discussed in detail in this paper.

  9. Traversable wormholes the Roman ring

    Visser, M


    In this brief report I introduce a yet another class of geometries for which semi-classical chronology protection theorems are of dubious physical reliability. I consider a ``Roman ring'' of traversable wormholes, wherein a number of wormholes are arranged in a ring in such a manner that no subset of wormholes is near to chronology violation, though the combined system can be arbitrarily close to chronology violation. I show that (with enough wormholes in the ring) the gravitational vacuum polarization (the expectation value of the quantum stress-energy tensor) can be made arbitrarily small. In particular the back-reaction can be kept arbitrarily small all the way to the ``reliability horizon''---so that semi-classical quantum gravity becomes unreliable before the gravitational back reaction becomes large.

  10. Ring vortex solitons in nonlocal nonlinear media

    Briedis, D.; Petersen, D.E.; Edmundson, D.;


    or higher charge fundamental vortices as well as higher order (multiple ring) vortex solitons. Our results pave the way for experimental observation of stable vortex rings in other nonlocal nonlinear systems including Bose-Einstein condensates with pronounced long-range interparticle interaction....

  11. On Exchange QB∞-Rings

    Huanyin Chen


    In this paper, we introduce a new class of rings, the QB∞-rings. We investigate necessary and sufficient conditions under which an exchange ring is a QB∞-ring. The modules over an exchange QB∞-ring are studied. Also, we prove that every regular square matrix over an exchange QB∞-ring admits a diagonal reduction by pseudo-invertible matrices.

  12. Neutrosophic LA-Semigroup Rings

    Mumtaz Ali


    Full Text Available Neutrosophic LA-semigroup is a midway structure between a neutrosophic groupoid and a commutative neutrosophic semigroup. Rings are the old concept in algebraic structures. We combine the neutrosophic LA-semigroup and ring together to form the notion of neutrosophic LA-semigroup ring. Neutrosophic LAsemigroup ring is defined analogously to neutrosophic group ring and neutrosophic semigroup ring.

  13. Optimum solution of dual-ring double-scattering system for an incident beam with given phase space for proton beam spreading

    Takada, Y


    A systematic method is given for deriving optimum scatterer parameters for the dual-ring double-scattering system for the incident proton beam with the given phase space parameters. This is accomplished by relating it to the known optimum solution for zero-emittance beam. Limitations on the phase space parameters of the beam incident on the first scatterer have been clarified to obtain such valid solutions. It is shown that the dual-ring double-scattering method can be applied to an incident beam with emittance as large as 100-200 pi mm mrad. The effect of the change of phase space parameters on the lateral distribution has been investigated. It was found that the larger the emittance of the beam, the more sensitive the fluence distribution is to the change of phase space parameters. The effect of the different emittances of the incident beam in x-theta, y-phi spaces is discussed. It is shown that lateral distribution is sensitive to the misalignment of the beam.

  14. Gulf ring algae

    Although they rank among the tiniest of the microspcopic phytoplankton, coccolithophore algae aid oceanographers studying the Gulf Stream rings and the ring boundaries. The algal group could help to identify more precisely the boundary of the warm rings of water that spin off from the Gulf Stream and become independent pools of warm water in the colder waters along the northeastern U.S. coast.Coccolithophore populations in the Gulf Stream rings intrigue oceanographers for two reasons: The phytoplankton are subjected to an environment that changes every few days, and population explosions within one coccolithophore species seem to be associated with changes in the characteristics of ocean water, said Pat Blackwelder, an associate professor at the Nova Oceanographic Center in Dania, Fla. She is one of many studying the physics, chemistry, and biology of warm core rings. A special oceanography session on these rings was held at the recent AGU Fall Meeting/ASLO Winter Meeting.

  15. Token Ring Project

    Adela Ionescu


    Full Text Available Ring topology is a simple configuration used to connect processes that communicate among themselves. A number of network standards such as token ring, token bus, and FDDI are based on the ring connectivity. This article will develop an implementation of a ring of processes that communicate among themselves via pipe links. The processes are nodes in the ring. Each process reads from its standard input and writes in its standard output. N-1 process redirects the its standard output to a standard input of the process through a pipe. When the ring-structure is designed, the project can be extended to simulate networks or to implement algorithms for mutual exclusion

  16. A topologically driven glass in ring polymers

    Michieletto, Davide


    The static and dynamic properties of ring polymers in concentrated solutions remains one of the last deep unsolved questions in polymer physics. At the same time, the nature of the glass transition in polymeric systems is also not well understood. In this work, we study a novel glass transition in systems made of circular polymers by exploiting the topological constraints that are conjectured to populate concentrated solutions of rings. We show that such rings strongly interpenetrate through one another, generating an extensive network of topological interactions that dramatically affects their dynamics. We show that a kinetically arrested state can be induced by randomly pinning a small fraction of the rings. This occurs well above the classical glass transition temperature at which microscopic mobility is lost. Our work both demonstrates the existence of long-lived inter-ring penetrations and realizes a novel, topologically induced, glass transition.

  17. Dichloro-Cycloazatriphosphane: The Missing Link between N2 P2 and P4 Ring Systems in the Systematic Development of NP Chemistry.

    Bresien, Jonas; Hinz, Alexander; Schulz, Axel; Suhrbier, Tim; Thomas, Max; Villinger, Alexander


    A dichloro-cycloazatriphosphane that incorporates a cyclic NP3 backbone could be synthesized using knowledge gained from the chemistry of N2 P2 and P4 ring systems. It fills the gap between the congeneric compounds [ClP(μ-NR)]2 and [ClP(μ-PR)]2 (R=sterically demanding substituent), and thus contributes to the systematic development of nitrogen-phosphorus chemistry in general. The title compound was studied with respect to its formation via a labile aminodiphosphene, which readily underwent different rearrangement reactions depending on the solvent. All compounds were fully characterized by experimental and computational methods. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Comparative gene expression analysis among vocal learners (Bengalese finch and budgerigar and non-learners (quail and ring dove reveals variable cadherin expressions in the vocal system

    Eiji eMatsunaga


    Full Text Available Birds use various vocalizations to communicate with one another, and some are acquired through learning. So far, three families of birds (songbirds, parrots, and hummingbirds have been identified as having vocal learning ability. Previously, we found that cadherins, a large family of cell-adhesion molecules, show vocal control-area-related expression in a songbird, the Bengalese finch. To investigate the molecular basis of evolution in avian species, we conducted comparative analysis of cadherin expressions in the vocal and other neural systems among vocal learners (Bengalese finch and budgerigar and a non-learner (quail and ring dove. The gene expression analysis revealed that cadherin expressions were more variable in vocal and auditory areas compared to vocally unrelated areas such as the visual areas among these species. Thus, it appears that such diverse cadherin expressions might have been related to generating species diversity in vocal behavior during the evolution of avian vocal learning. 

  19. Technique distribuee de gestion de la charge sur le reseau electrique et ring-tree: Un nouveau systeme de communication P2P

    Ayoub, Simon

    Le reseau de distribution et de transport de l'electricite se modernise dans plusieurs pays dont le Canada. La nouvelle generation de ce reseau que l'on appelle smart grid, permet entre autre l'automatisation de la production, de la distribution et de la gestion de la charge chez les clients. D'un autre cote, des appareils domestiques intelligents munis d'une interface de communication pour des applications du smart grid commencent a apparaitre sur le marche. Ces appareils intelligents pourraient creer une communaute virtuelle pour optimiser leurs consommations d'une facon distribuee. La gestion distribuee de ces charges intelligentes necessite la communication entre un grand nombre d'equipements electriques. Ceci represente un defi important a relever surtout si on ne veut pas augmenter le cout de l'infrastructure et de la maintenance. Lors de cette these deux systemes distincts ont ete concus : un systeme de communication peer-to-peer, appele Ring-Tree, permettant la communication entre un nombre important de noeuds (jusqu'a de l'ordre de grandeur du million) tel que des appareils electriques communicants et une technique distribuee de gestion de la charge sur le reseau electrique. Le systeme de communication Ring-Tree inclut une nouvelle topologie reseau qui n'a jamais ete definie ou exploitee auparavant. Il inclut egalement des algorithmes pour la creation, l'exploitation et la maintenance de ce reseau. Il est suffisamment simple pour etre mis en oeuvre sur des controleurs associes aux dispositifs tels que des chauffe-eaux, chauffage a accumulation, bornes de recharges electriques, etc. Il n'utilise pas un serveur centralise (ou tres peu, seulement lorsqu'un noeud veut rejoindre le reseau). Il offre une solution distribuee qui peut etre mise en oeuvre sans deploiement d'une infrastructure autre que les controleurs sur les dispositifs vises. Finalement, un temps de reponse de quelques secondes pour atteindre 1'ensemble du reseau peut etre obtenu, ce qui est

  20. Photochemistry of 1,4-Dihydropyridine Derivatives: Diradical Formation, Delocalization and Trapping as a Route to Novel Tricyclic and Tetracyclic Nitrogen Heterocyclic Ring Systems

    Nader A. Al-Jalal


    Full Text Available Irradiation of an acetonitrile solution of 4-aryl-3,5-dibenzoyl-1,4-dihydropyridine derivatives 1a–c and maleimides 2a–c using medium pressure Hg-arc lamp (λ > 290 nm afforded three different cycloadducts 4, 5, 6 in addition to the oxidation products 3. These results indicate that compounds 1a–c undergoes intermolecular cycloaddition reaction through three biradical intermediates and behave photochemically different than those reported previously for the analogous 3,5-diacetyl and 3,5-dicarboxylic acid derivatives. The present work also offers simple access to novel tricyclic and tetracyclic nitrogen heterocyclic ring systems of potential biological and synthetic applications. The structure of the photoproducts was established spectroscopically and by single crystal X-ray crystallography.

  1. On -Coherent Endomorphism Rings

    Li-Xin Mao


    A ring is called right -coherent if every principal right ideal is finitely presented. Let $M_R$ be a right -module. We study the -coherence of the endomorphism ring of $M_R$. It is shown that is a right -coherent ring if and only if every endomorphism of $M_R$ has a pseudokernel in add $M_R; S$ is a left -coherent ring if and only if every endomorphism of $M_R$ has a pseudocokernel in add $M_R$. Some applications are given.

  2. Physics of quantum rings

    Fomin, Vladimir M. (ed.) [Leibniz Institute for Solid State and Materials Research, Dresden (Germany)


    Presents the new class of materials of quantum rings. Provides an elemental basis for low-cost high-performance devices promising for electronics, optoelectronics, spintronics and quantum information processing. Explains the physical properties of quantum rings to cover a gap in scientific literature. Presents the application of most advanced nanoengineering and nanocharacterization techniques. This book deals with a new class of materials, quantum rings. Innovative recent advances in experimental and theoretical physics of quantum rings are based on the most advanced state-of-the-art fabrication and characterization techniques as well as theoretical methods. The experimental efforts allow to obtain a new class of semiconductor quantum rings formed by capping self-organized quantum dots grown by molecular beam epitaxy. Novel optical and magnetic properties of quantum rings are associated with non-trivial topologies at the nanoscale. An adequate characterization of quantum rings is possible on the basis of modern characterization methods of nanostructures, such as Scanning Tunneling Microscopy. A high level of complexity is demonstrated to be needed for a dedicated theoretical model to adequately represent the specific features of quantum rings. The findings presented in this book contribute to develop low-cost high-performance electronic, spintronic, optoelectronic and information processing devices based on quantum rings.

  3. Ring Around a Galaxy


    Space Telescope Science Institute astronomers are giving the public chances to decide where to aim NASA's Hubble Space Telescope. Guided by 8,000 Internet voters, Hubble has already been used to take a close-up, multi-color picture of the most popular object from a list of candidates, the extraordinary 'polar-ring' galaxy NGC 4650A. Located about 130 million light-years away, NGC 4650A is one of only 100 known polar-ring galaxies. Their unusual disk-ring structure is not yet understood fully. One possibility is that polar rings are the remnants of colossal collisions between two galaxies sometime in the distant past, probably at least 1 billion years ago. What is left of one galaxy has become the rotating inner disk of old red stars in the center. Meanwhile, another smaller galaxy which ventured too close was probably severely damaged or destroyed. The bright bluish clumps, which are especially prominent in the outer parts of the ring, are regions containing luminous young stars, examples of stellar rebirth from the remnants of an ancient galactic disaster. The polar ring appears to be highly distorted. No regular spiral pattern stands out in the main part of the ring, and the presence of young stars below the main ring on one side and above on the other shows that the ring is warped and does not lie in one plane. Determining the typical ages of the stars in the polar ring is an initial goal of our Polar Ring Science Team that can provide a clue to the evolution of this unusual galaxy. The HST exposures were acquired by the Hubble Heritage Team, consisting of Keith Noll, Howard Bond, Carol Christian, Jayanne English, Lisa Frattare, Forrest Hamilton, Anne Kinney and Zolt Levay, and guest collaborators Jay Gallagher (University of Wisconsin-Madison), Lynn Matthews (National Radio Astronomy Observatory-Charlottesville), and Linda Sparke (University of Wisconsin-Madison).

  4. Design of a loop resonator with a split-ring-resonator (SRR) for a human-body coil in 3 T MRI systems

    Son, Hyeok Woo; Cho, Young Ki; Kim, Byung Mun; Back, Hyun Man; Yoo, Hyoungsuk


    A new radio-frequency (RF) resonator for Nuclear Magnetic Resonance (NMR) imaging at clinical magnetic resonance imaging (MRI) systems is proposed in this paper. An approach based on the effects of the properties of metamaterials in split-ring resonators (SRRs) is used to design a new loop resonator with a SRR for NMR imaging. This loop resonator with a SRR is designed for NMR imaging at 3 T MRI systems. The 3D electromagnetic simulation was used to optimize the design of the proposed RF resonator and analyze it's performance at 3 T MRI systems. The proposed RF resonator provides strong penetrating magnetic fields at the center of the human phantom model, approximately 10%, as compared to the traditional loop-type RF resonator used for NMR imaging at clinical MRI systems. We also designed an 8-channel body coil for human-body NMR imaging by using the proposed loop resonator with a SRR. This body coil also produces more homogeneous and highly penetrating magnetic fields into the human phantom model.

  5. Algorithms for finite rings

    Ciocanea Teodorescu I.,


    In this thesis we are interested in describing algorithms that answer questions arising in ring and module theory. Our focus is on deterministic polynomial-time algorithms and rings and modules that are finite. The first main result of this thesis is a solution to the module isomorphism problem in

  6. Revocable Ring Signature

    Dennis Y. W. Liu; Joseph K. Liu; Yi Mu; Willy Susilo; Duncan S. Wong


    Group signature allows the anonymity of a real signer in a group to be revoked by a trusted party called group manager. It also gives the group manager the absolute power of controlling the formation of the group. Ring signature, on the other hand, does not allow anyone to revoke the signer anonymity, while allowing the real signer to forma group (also known as a ring) arbitrarily without being controlled by any other party. In this paper, we propose a new variant for ring signature, called Revocable Ring Signature. The signature allows a real signer to form a ring arbitrarily while allowing a set of authorities to revoke the anonymity of the real signer. This new variant inherits the desirable properties from both group signature and ring signature in such a way that the real signer will be responsible for what it has signed as the anonymity is revocable by authorities while the real signer still has the freedom on ring formation. We provide a formal security model for revocable ring signature and propose an efficient construction which is proven secure under our security model.

  7. Illustration of Saturn's Rings


    This illustration shows a close-up of Saturn's rings. These rings are thought to have formed from material that was unable to form into a Moon because of tidal forces from Saturn, or from a Moon that was broken up by Saturn's tidal forces.

  8. The Fermilab recycler ring

    Martin Hu


    The Fermilab Recycler is a permanent magnet storage ring for the accumulation of antiprotons from the Antiproton Source, and the recovery and cooling of the antiprotons remaining at the end of a Tevatron store. It is an integral part of the Fermilab III luminosity upgrade. The following paper describes the design features, operational and commissioning status of the Recycler Ring.

  9. EBT ring physics

    Uckan, N.A. (ed.)


    This workshop attempted to evaluate the status of the current experimental and theoretical understanding of hot electron ring properties. The dominant physical processes that influence ring formation, scaling, and their optimal behavior are also studied. Separate abstracts were prepared for each of the 27 included papers. (MOW)

  10. Smoke Ring Physics

    Huggins, Elisha


    The behavior of smoke rings, tornados, and quantized vortex rings in superfluid helium has many features in common. These features can be described by the same mathematics we use when introducing Ampere's law in an introductory physics course. We discuss these common features. (Contains 7 figures.)

  11. Algorithms for finite rings

    Ciocanea Teodorescu I.,


    In this thesis we are interested in describing algorithms that answer questions arising in ring and module theory. Our focus is on deterministic polynomial-time algorithms and rings and modules that are finite. The first main result of this thesis is a solution to the module isomorphism problem in

  12. Planetary rings - Theory

    Borderies, Nicole


    Theoretical models of planetary-ring dynamics are examined in a brief analytical review. The mathematical description of streamlines and streamline interactions is outlined; the redistribution of angular momentum due to collisions between particles is explained; and problems in the modeling of broad, narrow, and arc rings are discussed.

  13. Steroidal contraceptive vaginal rings.

    Sarkar, N N


    The development of steroid-releasing vaginal rings over the past three decades is reviewed to illustrate the role of this device as an effective hormonal contraceptive for women. Vaginal rings are made of polysiloxane rubber or ethylene-vinyl-acetate copolymer with an outer diameter of 54-60 mm and a cross-sectional diameter of 4-9.5 mm and contain progestogen only or a combination of progestogen and oestrogen. The soft flexible combined ring is inserted in the vagina for three weeks and removed for seven days to allow withdrawal bleeding. Progesterone/progestogen-only rings are kept in for varying periods and replaced without a ring-free period. Rings are in various stages of research and development but a few, such as NuvaRing, have reached the market in some countries. Women find this method easy to use, effective, well tolerated and acceptable with no serious side-effects. Though the contraceptive efficacy of these vaginal rings is high, acceptability is yet to be established.

  14. Radiation from structured-ring resonators

    Maling, B; Craster, R V


    We investigate the scalar-wave resonances of systems composed of identical Neumann-type inclusions arranged periodically around a circular ring. Drawing on natural similarities with the undamped Rayleigh-Bloch waves supported by infinite linear arrays, we deduce asymptotically the exponentially small radiative damping in the limit where the ring radius is large relative to the periodicity. In our asymptotic approach, locally linear Rayleigh-Bloch waves that attenuate exponentially away from the ring are matched to a ring-scale WKB-type wave field. The latter provides a descriptive physical picture of how the mode energy is transferred via tunnelling to a circular evanescent-to-propagating transition region a finite distance away from the ring, from where radiative grazing rays emanate to the far field. Excluding the zeroth-order standing-wave modes, the position of the transition circle bifurcates with respect to clockwise and anti-clockwise contributions, resulting in striking spiral wavefronts.

  15. Computational and ESR studies of electron attachment to decafluorocyclopentane, octafluorocyclobutane, and hexafluorocyclopropane: electron affinities of the molecules and the structures of their stable negative ions as determined from 13C and 19F hyperfine coupling constants.

    ElSohly, Adel M; Tschumper, Gregory S; Crocombe, Richard A; Wang, Jih Tzong; Williams, Ffrancon


    High-resolution ESR spectra of the ground-state negative ions of hexafluorocyclopropane (c-C3F6*-), octafluorocyclobutane (c-C4F8*-), and decafluorocyclopentane (c-C5F10*-) are reported and their isotropic 19F hyperfine coupling constants (hfcc) of 198.6 +/- 0.4 G, 147.6 +/- 0.4 G, and 117.9 +/- 0.4 G, respectively, are in inverse ratio to the total number of fluorine atoms per anion. Together with the small value of 5.2 +/- 0.4 G determined for the isotropic 13C hfcc of c-C4F8*-, these results indicate that in each case the singly occupied molecular orbital (SOMO) is delocalized over the equivalent fluorines and possesses a nodal plane through the carbon atoms of a time-averaged D(nh) structure. A series of quantum chemical computations were carried out to further characterize these anions and their neutral counterparts. Both the B3LYP density functional and second-order Møller-Plesset perturbation theory (MP2) indicate that c-C3F6*- adopts a D(3h) geometry and a (2)A2'' ground electronic state, that c-C4F8*- adopts a D(4h) geometry and a (2)A2u ground electronic state, and that c-C5F10*- adopts a C(s) structure and a (2)A' electronic state. Moreover, the 19F hyperfine coupling constants computed with the MP2 method and a high quality triple-zeta basis set are within 1% of the experimental values. Also, the values computed for the 13C hfcc of c-C4F8*- are consistent with the experimental value of 5.2 G. Therefore, in keeping with the ESR results, these negative ions derived from first-row elements can be characterized as pi* species. In addition, the hypervalency of these perfluorocycloalkane radical anions has been clarified.

  16. Jupiter's Rings: Sharpest View


    The New Horizons spacecraft took the best images of Jupiter's charcoal-black rings as it approached and then looked back at Jupiter. The top image was taken on approach, showing three well-defined lanes of gravel- to boulder-sized material composing the bulk of the rings, as well as lesser amounts of material between the rings. New Horizons snapped the lower image after it had passed Jupiter on February 28, 2007, and looked back in a direction toward the sun. The image is sharply focused, though it appears fuzzy due to the cloud of dust-sized particles enveloping the rings. The dust is brightly illuminated in the same way the dust on a dirty windshield lights up when you drive toward a 'low' sun. The narrow rings are confined in their orbits by small 'shepherding' moons.

  17. Prometheus Induced Vorticity In Saturns F Ring

    Sutton, Phil J


    Saturns rings are known to show remarkable real time variability in their structure. Many of which can be associated to interactions with nearby moons and moonlets. Possibly the most interesting and dynamic place in the rings, probably in the whole Solar System, is the F ring. A highly disrupted ring with large asymmetries both radially and azimuthally. Numerically non zero components to the curl of the velocity vector field (vorticity) in the perturbed area of the F ring post encounter are witnessed, significantly above the background vorticity. Within the perturbed area rich distributions of local rotations is seen located in and around the channel edges. The gravitational scattering of ring particles during the encounter causes a significant elevated curl of the vector field above the background F ring vorticity for the first 1-3 orbital periods post encounter. After 3 orbital periods vorticity reverts quite quickly to near background levels. This new found dynamical vortex life of the ring will be of grea...

  18. New Horizons Imaging of Jupiter's Main Ring

    Throop, Henry B.; Showalter, Mark Robert; Dones, Henry C. Luke; Hamilton, D. P.; Weaver, Harold A.; Cheng, Andrew F.; Stern, S. Alan; Young, Leslie; Olkin, Catherine B.; New Horizons Science Team


    New Horizons took roughly 520 visible-light images of Jupiter's ring system during its 2007 flyby, using the spacecraft's Long-Range Reconnaissance Imager (LORRI). These observations were taken over nine days surrounding Jupiter close-approach. They span a range in distance of 30 - 100 RJ, and a phase angle range of 20 - 174 degrees. The highest resolution images -- more than 200 frames -- were taken at a resolution approaching 20 km/pix.We will present an analysis of this dataset, much of which has not been studied in detail before. Our results include New Horizons' first quantitative measurements of the ring's intrinsic brightness and variability. We will also present results on the ring's azimuthal and radial structure. Our measurements of the ring's phase curve will be used to infer properties of the ring's dust grains.Our results build on the only previous analysis of the New Horizons Jupiter ring data set, presented in Showalter et al (2007, Science 318, 232-234), which detected ring clumps and placed a lower limit on the population of undetected ring-moons.This work was supported by NASA's OPR program.

  19. Ring-Resonator/Sol-Gel Interferometric Immunosensor

    Bearman, Gregory; Cohen, David


    A proposed biosensing system would be based on a combination of (1) a sensing volume containing antibodies immobilized in a sol-gel matrix and (2) an optical interferometer having a ring resonator configuration. The antibodies would be specific to an antigen species that one seeks to detect. In the ring resonator of the proposed system, light would make multiple passes through the sensing volume, affording greater interaction length and, hence, greater antibody- detection sensitivity.

  20. Non-contacting fluid ring seal systems for railcar axle bearing systems: Fifth quarterly report, June 16, 1988--September 15, 1988


    During this fifth quarter the evaluation of D-size fluid ring sealed roller bearing assemblies was completed with the evaluation of seal configuration MT 3008 and 3016, 3016a and 3016b (different static contact seal concepts), when exposed to intensive dust and rain storms generated within an enclosure surrounding the nondriven side of test rig /number sign/3 over the entire speed range from 0 to 1220 RPM bearing test speed. During the test rig /number sign/3 shake down test runs it became apparent that the intensity of the dust and rain storms surrounding the fluid ring sealed bearing end within the ''mini'' climate chamber could be appropriately observed through small windows at 12:00 and 6:00 o'clock provided in the endwall of the ''mini-climate'' chamber, rig /number sign/3 was accordingly modified and the dust and rain exposure tests were conducted at numerous levels of severity. 6 figs.

  1. Behavioral Mapless Navigation Using Rings

    Monroe, Randall P.; Miller, Samuel A.; Bradley, Arthur T.


    This paper presents work on the development and implementation of a novel approach to robotic navigation. In this system, map-building and localization for obstacle avoidance are discarded in favor of moment-by-moment behavioral processing of the sonar sensor data. To accomplish this, we developed a network of behaviors that communicate through the passing of rings, data structures that are similar in form to the sonar data itself and express the decisions of each behavior. Through the use of these rings, behaviors can moderate each other, conflicting impulses can be mediated, and designers can easily connect modules to create complex emergent navigational techniques. We discuss the development of a number of these modules and their successful use as a navigation system in the Trinity omnidirectional robot.

  2. Important Mutations Contributing to High-Level Penicillin Resistance in Taiwan(19F)-14, Taiwan(23F)-15, and Spain(23F)-1 of Streptococcus pneumoniae Isolated from Taiwan.

    Liu, Esther Yip-Mei; Chang, Jen-Chang; Lin, Jung-Chung; Chang, Feng-Yee; Fung, Chang-Phone


    Penicillin-resistant Streptococcus pneumoniae is a serious concern worldwide. In this study, we analyzed the cause of β-lactam resistance in pandemic multidrug-resistant clones. A total of 41 penicillin-nonsusceptible clinical isolates were collected from 1996 to 2012. Sero- and molecular typing confirmed that these isolates were clonal types of Taiwan(19F)-14, Taiwan(23F)-15, and Spain(23F)-1. Sero-switching was found in four isolates. All isolates were multidrug resistant. Sequencing analysis of the penicillin binding proteins (PBPs) was performed on PBP1a, 2b, and 2x, and a large number of mutations were identified in comparing to clinical penicillin-susceptible isolates and the recipient strain R6 used for homologous recombination. The T451A substitution was the key amino acid in PBP2b that contributed to penicillin resistance. T338A in PBP2x played a role in resistance and reached the highest level of resistance when combined with other mutations in PBP2x. High-level penicillin resistance could not be obtained without the combination of mutations in PBP1a with PBP2b and 2x. The amino acid substitutions in PBP1a, 2b, and 2x were the crucial factors for β-lactam resistance.

  3. Correlated fluorine diffusion and ionic conduction in the nanocrystalline F(-) solid electrolyte Ba(0.6)La(0.4)F(2.4)-(19)F T1(ρ) NMR relaxation vs. conductivity measurements.

    Preishuber-Pflügl, F; Bottke, P; Pregartner, V; Bitschnau, B; Wilkening, M


    Chemical reactions induced by mechanical treatment may give access to new compounds whose properties are governed by chemical metastability, defects introduced and the size effects present. Their interplay may lead to nanocrystalline ceramics with enhanced transport properties being useful to act as solid electrolytes. Here, the introduction of large amounts of La into the cubic structure of BaF2 served as such an example. The ion transport properties in terms of dc-conductivity values of the F(-) anion conductor Ba1-xLaxF2+x (here with x = 0.4) considerably exceed those of pure, nanocrystalline BaF2. So far, there is only little knowledge about activation energies and jump rates of the elementary hopping processes. Here, we took advantage of both impedance spectroscopy and (19)F NMR relaxometry to get to the bottom of ion jump diffusion proceeding on short-range and long-range length scales in Ba0.6La0.4F2.4. While macroscopic transport is governed by an activation energy of 0.55 to 0.59 eV, the elementary steps of hopping seen by NMR are characterised by much smaller activation energies. Fortunately, we were able to deduce an F(-) self-diffusion coefficient by the application of spin-locking NMR relaxometry.

  4. Absolute NMR shielding scales and nuclear spin-rotation constants in (175)LuX and (197)AuX (X = (19)F, (35)Cl, (79)Br and (127)I).

    Demissie, Taye B; Jaszuński, Michał; Komorovsky, Stanislav; Repisky, Michal; Ruud, Kenneth


    We present nuclear spin-rotation constants, absolute nuclear magnetic resonance (NMR) shielding constants, and shielding spans of all the nuclei in (175)LuX and (197)AuX (X = (19)F, (35)Cl, (79)Br, (127)I), calculated using coupled-cluster singles-and-doubles with a perturbative triples (CCSD(T)) correction theory, four-component relativistic density functional theory (relativistic DFT), and non-relativistic DFT. The total nuclear spin-rotation constants determined by adding the relativistic corrections obtained from DFT calculations to the CCSD(T) values are in general in agreement with available experimental data, indicating that the computational approach followed in this study allows us to predict reliable results for the unknown spin-rotation constants in these molecules. The total NMR absolute shielding constants are determined for all the nuclei following the same approach as that applied for the nuclear spin-rotation constants. In most of the molecules, relativistic effects significantly change the computed shielding constants, demonstrating that straightforward application of the non-relativistic formula relating the electronic contribution to the nuclear spin-rotation constants and the paramagnetic contribution to the shielding constants does not yield correct results. We also analyze the origin of the unusually large absolute shielding constant and its relativistic correction of gold in AuF compared to the other gold monohalides.

  5. Absolute NMR shielding scales and nuclear spin–rotation constants in {sup 175}LuX and {sup 197}AuX (X = {sup 19}F, {sup 35}Cl, {sup 79}Br and {sup 127}I)

    Demissie, Taye B., E-mail:; Komorovsky, Stanislav; Repisky, Michal; Ruud, Kenneth [Centre for Theoretical and Computational Chemistry, Department of Chemistry, UiT The Arctic University of Norway, N-9037 Tromsø (Norway); Jaszuński, Michał [Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44, 01 224 Warszawa (Poland)


    We present nuclear spin–rotation constants, absolute nuclear magnetic resonance (NMR) shielding constants, and shielding spans of all the nuclei in {sup 175}LuX and {sup 197}AuX (X = {sup 19}F, {sup 35}Cl, {sup 79}Br, {sup 127}I), calculated using coupled-cluster singles-and-doubles with a perturbative triples (CCSD(T)) correction theory, four-component relativistic density functional theory (relativistic DFT), and non-relativistic DFT. The total nuclear spin–rotation constants determined by adding the relativistic corrections obtained from DFT calculations to the CCSD(T) values are in general in agreement with available experimental data, indicating that the computational approach followed in this study allows us to predict reliable results for the unknown spin–rotation constants in these molecules. The total NMR absolute shielding constants are determined for all the nuclei following the same approach as that applied for the nuclear spin–rotation constants. In most of the molecules, relativistic effects significantly change the computed shielding constants, demonstrating that straightforward application of the non-relativistic formula relating the electronic contribution to the nuclear spin–rotation constants and the paramagnetic contribution to the shielding constants does not yield correct results. We also analyze the origin of the unusually large absolute shielding constant and its relativistic correction of gold in AuF compared to the other gold monohalides.

  6. Absolute NMR shielding scales and nuclear spin-rotation constants in 175LuX and 197AuX (X = 19F, 35Cl, 79Br and 127I)

    Demissie, Taye B.; Jaszuński, Michał; Komorovsky, Stanislav; Repisky, Michal; Ruud, Kenneth


    We present nuclear spin-rotation constants, absolute nuclear magnetic resonance (NMR) shielding constants, and shielding spans of all the nuclei in 175LuX and 197AuX (X = 19F, 35Cl, 79Br, 127I), calculated using coupled-cluster singles-and-doubles with a perturbative triples (CCSD(T)) correction theory, four-component relativistic density functional theory (relativistic DFT), and non-relativistic DFT. The total nuclear spin-rotation constants determined by adding the relativistic corrections obtained from DFT calculations to the CCSD(T) values are in general in agreement with available experimental data, indicating that the computational approach followed in this study allows us to predict reliable results for the unknown spin-rotation constants in these molecules. The total NMR absolute shielding constants are determined for all the nuclei following the same approach as that applied for the nuclear spin-rotation constants. In most of the molecules, relativistic effects significantly change the computed shielding constants, demonstrating that straightforward application of the non-relativistic formula relating the electronic contribution to the nuclear spin-rotation constants and the paramagnetic contribution to the shielding constants does not yield correct results. We also analyze the origin of the unusually large absolute shielding constant and its relativistic correction of gold in AuF compared to the other gold monohalides.

  7. Mise en évidence par RMN du 19F d'une distorsion des octaèdres dans la solution solide CsCaF 3- xH x de type perovskite (0 ≤ x ≤ 1,70)

    Pezat, M.; Senegas, J.; Villeneuve, G.; Park, H. H.; Tressaud, A.


    19F and 1H NMR investigations have been carried out on three powder samples of CsCaF 3- xH x composition (0 ≤ x ≤ 1.70), and on a single crystal of CsCaF 3. It appears that the spectra of 19F are consistent with a distortion of the Ca(F,H) 6 octahedra involving either lower symmetry or a random distribution of a c4-maxis with respect to the crystallographic directions.

  8. Local loop near-rings

    Franetič, Damir


    We study loop near-rings, a generalization of near-rings, where the additive structure is not necessarily associative. We introduce local loop near-rings and prove a useful detection principle for localness.

  9. Theodolite Ring Lights

    Clark, David


    Theodolite ring lights have been invented to ease a difficulty encountered in the well-established optical-metrology practice of using highly reflective spherical tooling balls as position references. A theodolite ring light produces a more easily visible reflection and eliminates the need for an autocollimating device. A theodolite ring light is a very bright light source that is well centered on the optical axis of the instrument. It can be fabricated, easily and inexpensively, for use on a theodolite or telescope of any diameter.

  10. Heavy ion storage rings

    Schuch, R.


    A brief overview of synchrotron storage rings for heavy ions, which are presently under construction in different accelerator laboratories is given. Ions ranging from protons up to uranium ions at MeV/nucleon energies will be injected into these rings using multiturn injection from the accelerators available or being built in these laboratories. After injection, it is planned to cool the phase space distribution of the ions by merging them with cold electron beams or laser beams, or by using stochastic cooling. Some atomic physics experiments planned for these rings are presented.

  11. Satellite And Propeller Migration In Saturn's Rings

    Crida, Aurelien; Charnoz, S.; Papaloizou, J.; Salmon, J.


    Saturn's rings host satellites like Pan and Daphnis, and smaller bodies like the recently discovered propellers (Tiscareno et al. 2006). These bodies interact gravitationally with the rings. Actually, the resulting perturbations on the ring system have revealed the presence of embedded objects (the Encke and Keeler gaps associated with Pan and Daphnis respectively, the little two-folded structures called propellers tracing the scattering of ring particles by some embedded small objects). Reciprocally, the rings must act on the embedded bodies, leading to their migration. Here, we study how the standard theory of planetary migration applies in Saturn's ring, where the pressure is negligible in contrast with standard protoplanetary disks. Pan and Daphnis should be in standard type II migration, governed by the global disk evolution. Therefore, their presence and position provide constraints on the history of the A-ring, which can be studied using numerical simulations of disk-satellite interactions. The propellers are fully embedded in the disc, and therefore should be subject to type I migration. The simple impulse approximation used by Lin and Papaloi zou (1979) to derive the one-sided torque is particularly suited to this case. Refining their calculation, taking density variations into account, and discussing the possibility for these bodies to enter the type III, runaway regime of migration, we aim at estimating a possible migration rate for these propellers, to be compared to the system life time.

  12. On the possible triple central star system of PN SuWt 2: No m\\'enage \\`a trois at the heart of the Wedding Ring

    Jones, David


    SuWt 2 is a planetary nebula consisting of a bright ring-like waist from which protrude faint extended lobes - a morphology believed to be typical of progenitors which have experienced a close-binary evolution. Previous observations of NSV 19992, the star at the projected centre of SuWt 2, have found it to comprise two A-type stars in a 4.9 day eclipsing orbit, neither of which could be the nebular progenitor. Radial velocity studies provided a hint that the systemic velocity of this double A-type binary might be varying over time, suggesting the presence of a third component hypothesised to be the nebular progenitor. Here, we present an extensive radial velocity monitoring study of NSV 19992, performed with the high-resolution echelle spectrograph UVES mounted on ESO's VLT, in order to constrain the possible variation in the systemic velocity of the A-type binary and its relation to the progenitor of SuWt 2. The observations, acquired over a period of approximately one year, show no evidence of variability i...

  13. 上海光源储存环束流轨道联锁系统升级%Storage ring beam orbit interlock system upgrade for SSRF

    耿合龙; 冷用斌; 周伟民; 赖龙伟; 沈通; 阎映炳


    Background: Required by machine malfunction analysis, the beam orbit interlock system for the storage ring needs to be upgraded at the Shanghai Synchrotron Radiation Facility (SSRF). Purpose: This study aims to implement an upgraded new interlock system that can label 140 interlock signals coming from different Beam Position Monitor (BPM) electronics and record all data in the new system. And the turn-by-turn data in the BPM electronics Post Mortem buffer will be latched whenever the interlock occurs. Methods: The interlock signals and the latch signals were transmitted through the optical fiber and processed in an NI PXI 7813R Field Programmable Gate Array (FPGA) board. NI PXI-8106 controller is configured to run Linux operation system for Input/Output Controller (IOC) of Experimental Physics and Industrial Control System (EPICS) and communicate with PXI 7813R board which processes all interlock signals. Results: All interlock signal processing and latched trigger signal output were achieved in the FPGA board. The new system was fully integrated to the main EPICS for the storage ring. And the system runs as expected. Conclusions: The online test data show that the new system can detect the first interlock signal caused by the machine abnormality while the turn-by-turn data are latched. The analysis of turn-by-turn data shows the first BPM electronics which sends the interlock signal. The result is consistent with the FPGA board. Meanwhile, beam orbit changes were observed during beam abortions.%针对上海光源机器故障分析的需求,对原有储存环束流轨道联锁系统进行升级,实现对储存环束流位置测量系统中140台束流位置监测器(Beam Position Monitor, BPM)电子学输出的联锁信号进行标记,同时锁存丟束过程中所有BPM电子学中的逐圈轨道数据。联锁信号的处理与锁存触发信号的输出在FPGA (Field Programmable Gate Array)内完成。该系统集成至储存环的物理

  14. High-Speed Ring Bus

    Wysocky, Terry; Kopf, Edward, Jr.; Katanyoutananti, Sunant; Steiner, Carl; Balian, Harry


    is no centralized arbitration or bus granting. The JPL design provides for autonomous synchronization of the nodes on the ring bus. An address-synchronous latency adjust buffer (LAB) has been designed that cannot get out of synchronization and needs no external input. Also, a priority-driven cable selection behavior has been programmed into each unit on the ring bus. This makes the bus able to connect itself up, according to a maximum redundancy priority system, without the need for computer intervention at startup. Switching around a failed or switched-off unit is also autonomous. The JPL bus provides a map of all the active units for the host computer to read and use for fault management. With regard to timing, this enhanced bus recognizes coordinated timing on a spacecraft as critical and addresses this with a single source of absolute and relative time, which is broadcast to all units on the bus with synchronization maintained to the tens of nanoseconds. Each BIU consists of up to five programmable triggers, which may be programmed for synchronization of events within the spacecraft of instrument. All JPL-formatted data transmitted on the ring bus are automatically time-stamped.

  15. The new dc power supply system for the main ring magnets of the 28 GeV CERN proton synchrotron

    Jahn, K; Steckmann, E


    High overload capacity, low residual ripple, exact reproducibility of periodic current pulses and very great reliability in long-term duty are essential requirements for a modern power supply system for feeding beam-guide magnets. These requirements can be met with certainty and at reasonable cost by the use of high-performance single-anode mercury-arc converters with suitable electronic control and protective equipment. (4 refs).

  16. Using an OPO laser system for recombination studies in a storage ring: LIR to n = 3 states of deuterium

    Justiniano, E.; Asp, S.; DeWitt, D.R.; Schuch, R. [Stockholm Univ. (Sweden). Dept. of Atomic Phys.; Andler, G. [Manne Siegbahn Lab., Stockholm Univ. (Sweden)


    We have investigated the use of a one-stage optical parametric oscillator (OPO) laser system for studies of laser induced radiative recombination (LIR) of stored ions. For the test case considered, LIR into n = 3 states of deuterium, we find that the energy resolution is limited by the broad linewidth of the OPO. Within this resolution, our LIR results are in good agreement with a theoretical average field induced threshold shift model. (orig.). 17 refs.

  17. Alkoxyallene-ynes: Selective Preparation of Bicyclo[5.3.0] Ring Systems Including a δ-Alkoxy Cyclopentadienone.

    Tap, Aurélien; Lecourt, Camille; Dhambri, Sabrina; Arnould, Mathieu; Galvani, Gilles; Nguyen, Van Buu Olivier; Jouanneau, Morgan; Férézou, Jean-Pierre; Ardisson, Janick; Lannou, Marie-Isabelle; Sorin, Geoffroy


    The development of an intramolecular rhodium(I)-catalyzed Pauson-Khand reaction of alkoxyallene-ynes with a proximal alkoxy group is reported. This reaction, in the presence of a [Rh(cycloocta-1,5-diene)Cl]2/propane-1,3-diylbis(diphenylphosphane) system under a CO atmosphere, constitutes a powerful tool for selectively accessing carbo- and heterobicyclo[5.3.0] frameworks featuring an enol ether moiety. Through this procedure, a straightforward access to guaiane skeletons with a tertiary hydroxy group at the C10 position was achieved.

  18. Ringed Seal Distribution Map

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains GIS layers that depict the known spatial distributions (i.e., ranges) of the five subspecies of ringed seals (Phoca hispida). It was produced...

  19. The g-2 ring


    The precise measurement of "g-2", the anomalous magnetic moment of the muon, required a special muon storage ring with electrostatic focussing and very accurate knowledge of the magnetic bending field. For more details see under photo 7405430.

  20. Modified Newton's rings: II

    Chaitanya, T Sai; Krishna, V Sai; Anandh, B Shankar; Umesh, K S


    In an earlier work (Shankar kumar Jha, A Vyas, O S K S Sastri, Rajkumar Jain & K S Umesh, 'Determination of wavelength of laser light using Modified Newton's rings setup', Physics Education, vol. 22, no.3, 195-202(2005)) reported by our group, a version of Newton's rings experiment called Modified Newton's rings was proposed. The present work is an extension of this work. Here, a general formula for wavelength has been derived, applicable for a plane of observation at any distance. A relation between the focal length and the radius curvature is also derived for a plano-convex lens which is essentially used as a concave mirror. Tracker, a video analysis software, freely downloadable from the net, is employed to analyze the fringes captured using a CCD camera. Two beams which give rise to interference fringes in conventional Newton's rings and in the present setup are clearly distinguished.

  1. A novel Beam-Down System for Solar Power Generation with Multi-Ring Central Reflectors and Molten Salt Thermal Storage

    Tamaura, Y.; Utamura, M.; Kaneko, H.; Hasuike, H.; Domingo, M.; Relloso, S.


    A new concept of beam-down solar power with thermal storage is proposed. The system is featured in an optical system with multi-ring central reflectors and a liquid film molten salt thermal receiver installed near ground level. Its feasibility study has been carried out and power generation cost as well as EPC cost has been estimated. To compensate the drawback to a beam-down solar concentrating system in optical losses, a new receiver concept of liquid film molten salt thermal receiver is designed to aim at higher thermal efficiency than that of tubular receiver. Molten salt liquid film is formed along the inner surface of the receiver wall. The liquid film flows down by gravity. It is shown that the liquid film receiver has a high heat exchange potential up to 2MW/m2 of solar beam flux on the inner wall surface and proved to be feasible. Assuming 24 hour continuous power generation located at Almeria Spain, conceptual designs for two capacities of 120MWt (commercial plant) and 20MWt (pilot plant) have been made. The height and the radius of the central receiver have been optimized as a result of trade off of optical loss and the cost of the central reflector and its support structure. The total cost of the Beam-Down will become 8.37 US cents/kWh, which will be competitive with coal and natural gas, when crude oil cost increases. TITECH (Tokyo Institute of Technology) plans to launch an international program to develop the innovative/cheaper solar tower beam--down concentrating system. (Author)

  2. Is the bell ringing?

    Francesco Poppi


    During the Nobel prize-winning UA1 experiment, scientists in the control room used to ring a bell if a particularly interesting event had occurred. Today, the “CMS Exotica hotline” routine produces a daily report that lists the exotic events that were recorded the day before.   Display of an event selected by the Exotica routine. Take just a very small fraction of the available data (max. 5%); define the events that you want to keep and set the parameters accordingly; run the Exotica routine and only look at the very few images that the system has selected for you. This is the recipe that a small team of CMS researchers has developed to identify the signals coming from possible new physics processes. “This approach does not replace the accurate data analysis on the whole set of data. However, it is a very fast and effective way to focus on just a few events that are potentially very interesting”, explains Maurizio Pierini (CERN), who developed the...

  3. Stability of Neptune's ring arcs in question

    Dumas, Christophe; Terrile, Richard J.; Smith, Bradford A.; Schneider, Glenn; Becklin, E. E.


    Although all four of the gas-giant planets in the Solar System have ring systems, only Neptune exhibits `ring arcs'-stable clumps of dust that are discontinuous from each other. Two basic mechanisms for confining the dust to these arcs have been proposed. The firstrelies on orbital resonances with two shepherding satellites, while the second invokes a single satellite (later suggested to be Galatea) to produce the observed ring arc structures. Here we report observations of the ring arcs and Galatea, which show that there isa mismatch between the locations of the arcs and the site of Galatea's co-rotation inclined resonance. This result calls into question Galatea's sole role in confining the arcs.

  4. Polar Ring Galaxies and Warps

    Combes, F.

    Polar ring galaxies, where matter is in equilibrium in perpendicular orbits around spiral galaxies, are ideal objects to probe the 3D shapes of dark matter halos. The conditions to constrain the halos are that the perpendicular system does not strongly perturb the host galaxy, or that it is possible to derive back its initial shape, knowing the formation scenario of the polar ring. The formation mechanisms are reviewed: mergers, tidal accretion, or gas accretion from cosmic filaments. The Tully-Fisher diagram for polar rings reveals that the velocity in the polar plane is higher than in the host plane, which can only be explained if the dark matter is oblate and flattened along the polar plane. Only a few individual systems have been studied in details, and 3D shapes of their haloes determined by several methods. The high frequency of warps could be explained by spontaneous bending instability, if the disks are sufficiently self-gravitating, which can put constraints on the dark matter flattening.

  5. Polar ring galaxies and warps

    Combes, F


    Polar ring galaxies, where matter is in equilibrium in perpendicular orbits around spiral galaxies, are ideal objects to probe the 3D shapes of dark matter halos. The conditions to constrain the halos are that the perpendicular system does not strongly perturb the host galaxy, or that it is possible to derive back its initial shape, knowing the formation scenario of the polar ring. The formation mechanisms are reviewed: mergers, tidal accretion, or gas accretion from cosmic filaments. The Tully-Fisher diagram for polar rings reveals that the velocity in the polar plane is higher than in the host plane, which can only be explained if the dark matter is oblate and flattened along the polar plane. Only a few individual systems have been studied in details, and 3D shapes of their haloes determined by several methods. The high frequency of warps could be explained by spontaneous bending instability, if the disks are sufficiently self-gravitating, which can put constraints on the dark matter flattening.

  6. Laser system for cooling of relativistic C{sup 3+}-ion beams in storage rings; Lasersystem zur Kuehlung relativistischer C{sup 3+}-Ionenstrahlen in Speicherringen

    Beck, Tobias


    Cold ion beams are essential for many precision experiments at storage rings. While spectroscopic experiments gain from the high energy resolution, collision experiments benefit from the increased luminosity. Furthermore, sympathetic cooling of exotic species is conceivable with the aid of cold ion beams. Besides the long established electron cooling, alternative cooling methods are gaining in importance, especially for high energy particles. In the past, experiments to cool ions with lasers were performed. Because of the matching wavelength and output power, frequency doubled Argon-ion lasers at 257 nm were used during these experiments. Due to the strongly limited scanning potential of these systems, it was not possible to cool the full inertia spread of the ion beams. A new laser system was developed in this thesis because of the lack of commercial alternatives. After the characterization of the system, it was tested during a beamtime at the Experimentierspeicherring (ESR) at the Gesellschaft fuer Schwerionenforschung (GSI). The completely solid state based system delivers up to 180 mW of output power at 257 nm and is modehop free tunable up to 16 GHz in 10 ms at this wavelength. By using efficient diode lasers, the new system consumes considerably less power than comparable Argon-ion lasers. The fundamental wavelength of 1028 nm is amplified up to 16 W with an Yb-doped fiber amplifier. Subsequently, the target wavelength of 257 nm is realized in two consecutive build-up cavities. Another diode laser, stabilized to a wavelength meter, serves as a frequency reference. This new laser system first came to operation during beamtime in August 2012, when relativistic C{sup 3+} ions with β=0.47 were cooled successfully. For the first time it was possible to access the whole inertia spread of a bunched ion beam without electron precooling. In contrast to prior experiments, only the laser frequency was scanned and not the bunching frequency of the ion beam. The results

  7. Investigation of 2D photonic crystal structure based channel drop filter using quad shaped photonic crystal ring resonator for CWDM system

    Chhipa, Mayur Kumar, E-mail:; Dusad, Lalit Kumar [Government Engineering College Ajmer, Rajasthan (India); Rajasthan Technical University, Kota, Rajasthan (India)


    In this paper, the design & performance of two dimensional (2-D) photonic crystal structure based channel drop filter is investigated using quad shaped photonic crystal ring resonator. In this paper, Photonic Crystal (PhC) based on square lattice periodic arrays of Gallium Indium Phosphide (GaInP) rods in air structure have been investigated using Finite Difference Time Domain (FDTD) method and photonic band gap is being calculated using Plane Wave Expansion (PWE) method. The PhC designs have been optimized for telecommunication wavelength λ= 1571 nm by varying the rods lattice constant. The number of rods in Z and X directions is 21 and 20, with lattice constant 0.540 nm it illustrates that the arrangement of Gallium Indium Phosphide (GaInP) rods in the structure which gives the overall size of the device around 11.4 µm × 10.8 µm. The designed filter gives good dropping efficiency using 3.298, refractive index. The designed structure is useful for CWDM systems. This device may serve as a key component in photonic integrated circuits. The device is ultra compact with the overall size around 123 µm{sup 2}.

  8. 深基环梁支护体系内力的研究%Loading of ring-beam support structure system in deep foundation ditch

    丁克胜; 王沛; 杨宝珠


    Ring-beam support structure system is a new-type structure in deep foundation pit support structure.It may produre a hamonious load and gain a high bearing capacity.Its calculation model is elast ic multi-support.when using the saper 93 progvam with plane and overall calcula tion,the results are rather identical with the real condition,so it is a simple and effeetive method.%深基环梁支护体系是深基支护的一种新型结构,它受力均衡,承载力高,计算模型为多向弹性支座,利用Saper 93 程序进行平面整体设计计算的结果与实际比较相符,是一种非常简捷、有效的计算方法,但其水平支撑系统的内力受多方面因素的影响较大.

  9. 量子环上粒子体系的计算%Computation for a System of Particles in a Quantum Ring



    对于量子环上带电粒子体系,组成本征函数的基矢数及哈密顿矩阵元素数都极大,数值计算量庞大.本文介绍在处理此问题时按轨道总角动量分类从基矢集中选择子基矢集的方法和技巧.应用计算机进行数值计算时,此方法比以往节省90%以上的时间.%A system of charged particles in a quantum ring consists of a great number of base vectors of eigenfunctions and Hamiltonian matrix elements,resulting in a huge amount of numerical computations.This paper describes a method for solving the problem according to a classification of orbital angular momentum.It introduces technique to select sub-vector sets from eigenvectors.The method reduces the computation by more than 90%.

  10. Nitration of Norcorrolatonickel(II): First Observation of a Diatropic Current in a System Comprising a Norcorrole Ring.

    Deng, Zhihong; Li, Xiaofang; Stępień, Marcin; Chmielewski, Piotr J


    A one-pot reaction of 5,14-bis(mesityl)-norcorrolatonickel(II) with isoamyl nitrite under mild reaction conditions resulted in the consecutive formation of 3-nitro-, 3,12-dinitro- and 3,16-dinitro-, 3,7,12-trinitro-, and 3,7,12,16-tetranitro-norcorrolatonickel(II) in 50-80% yield. The substituted macrocycles retained their antiaromatic character. The observed regioselectivity of the substitution was analyzed by comparing the relative energies of the DFT energy-optimized models of the radical or arenium cationic intermediates that can be formed upon reaction with NO2. The nitrated systems were characterized by high-resolution mass spectrometry, NMR and UV/Vis spectroscopy, X-ray diffraction analysis, cyclic voltammetry, and DFT calculations. A significant and systematic cathodic shift of the redox couples was observed to correlate with an increasing number of the NO2 group. A decrease of the LUMO energies in the tri- and tetra-nitrated products stabilizes mono- and bis-reduced complexes of these ligands. The reduction takes place on the macrocycle rather than on the metal ion leading to the consecutive formation of stable paramagnetic monoanion radicals and water-soluble diamagnetic dianions with an aromatic character, which were revealed by ESR and (1)H NMR measurements, respectively. The electronic structures of the reduced forms were analyzed by extensive TD-DFT calculations. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Descent from the form ring and Buchsbaum rings

    Schenzel, P


    There is a spectral sequence technique in order to estimate the local cohomology of a ring by the local cohomology of a certain form ring. As applications there are information on the descent of homological properties (Cohen-Macaulay, Buchsbaum etc.) from the form ring to the ring itself. In the case of Buchsbaum ring there is a discussion of the descent of the surjectivity of a natural map into the local cohomology.

  12. Neither moderate hypoxia nor mild hypoglycaemia alone causes any significant increase in cerebral [Ca2+]i: only a combination of the two insults has this effect. A 31P and 19F NMR study.

    Badar-Goffer, R S; Thatcher, N M; Morris, P G; Bachelard, H S


    (1) The energy state and free intracellular calcium concentration ([Ca2+]i) of superfused cortical slices were measured in moderate hypoxia (approximately 65 microM O2), in mild hypoglycaemia (0.5 mM glucose), and in combinations of the two insults using 19F and 31P NMR spectroscopy. (2) Neither hypoxia nor hypoglycaemia alone caused any significant change in [Ca2+]i. Hypoxia caused a 40% fall in phosphocreatine (PCr) content but not in ATP level, and hypoglycaemia produced a slight fall in both (as expected from previous studies). These changes in the energy state recovered on return to control conditions. (3) A combined sequential insult (hypoxia, followed by hypoxia plus hypoglycaemia) produced a 100% increase in [Ca2+]i and a decrease in PCr level to approximately 25% of control. The reverse combined sequential insult (hypoglycaemia, followed by hypoglycaemia plus hypoxia) had the same effect. On return to control conditions there was some decrease in [Ca2+]i and a small increase in PCr content, but neither recovered to control levels. (4) Exposure of the tissue to the combined simultaneous insult (hypoxia plus hypoglycaemia) immediately after the control spectra had been recorded resulted in a fivefold increase in [Ca2+]i and a similar decrease in PCr level to 20-25% of control. There was little if any change of [Ca2+]i or PCr level on return to control conditions. (5) These results are discussed in terms of metabolic adaptation of some but not all of the cortical cells to the single type of insult, which renders the tissues less vulnerable to the combined insult.

  13. Holomorphic Dynamics and Herman Rings

    Henriksen, Christian


    Existence theorem for Herman Rings of holomorphic mappings in a certain holomorphic family is given, using quasiconformal mappings. Proofs of topological properties of these Herman rings are given.......Existence theorem for Herman Rings of holomorphic mappings in a certain holomorphic family is given, using quasiconformal mappings. Proofs of topological properties of these Herman rings are given....

  14. An Arc in Saturn's G Ring

    Burns, Joseph A.; Hedman, M.; Tiscareno, M.; Porco, C.; Jones, G.; Roussos, E.; Krupp, N.


    The G ring is a narrow, faint ring located between the orbits of Janus and Mimas. Approximately 4000 km wide, it has a strongly asymmetric brightness profile with a sharp inner edge between 167,000 km and 168,000 km from Saturn's center and a more diffuse outer part. In Cassini images, a portion of the ring contains a bright arc that abuts the G-ring's inner edge and extends over 30 degrees in longitude. By tracking this arc over the first two years of the Cassini Mission, we find its orbital period is 0.80813 day, corresponding to a semi-major axis of 167,496 km. Since this location places the arc within 6 km of the Mimas 7:6 Co-rotation Eccentricity Resonance and within 12 km of the Mimas 7:6 Inner Lindblad Resonance, the arc is likely confined in longitude by Mimas just as Neptune's ring arcs are held in place by Galatea. The arc's longitude relative to Mimas is consistent with this model. Cassini now has the opportunity to study the dynamics of this sort of system in detail over a period of years. The arc, which may be the debris of a fragmented moon, may also supply the particles found in the rest of the G ring; micron-sized grains drift outwards by non-gravitational processes in this region. The G-ring is responsible for a broad, relatively modest decrease in the fluxes of magnetospheric charged particles. When Cassini passed over the G ring in the vicinity of the arc, on September 5, 2005, the MIMI instrument detected a particularly sharp and deep charged particle absorption signature. Such a pronounced charged particle absorption was not seen in the other G-ring passages that occurred longitudinally far from the arc. The nature of this absorption provides constraints on the population of large particles in this arc.

  15. Ringed accretion disks: equilibrium configurations

    Pugliese, D


    We investigate a model of ringed accretion disk, made up by several rings rotating around a supermassive Kerr black hole attractor. Each toroid of the ringed disk is governed by the General Relativity hydrodynamic Boyer condition of equilibrium configurations of rotating perfect fluids. Properties of the tori can be then determined by an appropriately defined effective potential reflecting the background Kerr geometry and the centrifugal effects. The ringed disks could be created in various regimes during the evolution of matter configurations around supermassive black holes. Therefore, both corotating and counterrotating rings have to be considered as being a constituent of the ringed disk. We provide constraints on the model parameters for the existence and stability of various ringed configurations and discuss occurrence of accretion onto the Kerr black hole and possible launching of jets from the ringed disk. We demonstrate that various ringed disks can be characterized by a maximum number of rings. We pr...

  16. Saturn's Other Ring Current

    Crary, F. J.


    Saturn's main rings orbit the planet within an atmosphere and ionosphere of water, oxygen and hydrogen, produced by meteoritic impacts on and ultraviolet photodesorbtion of the ring particles [Johnson et al., 2006; Luhmann et al., 2006; Tseng et al., 2010]. The neutral atmosphere itself has only been tentatively detected through ultraviolet fluorescents of OH [Hall et al., 1996] while the ionosphere was observed in situ by the Cassini spacecraft shortly after orbital insertion [Coates et al.,2005; Tokar et al. 2005, Waite et al. 2005]. Although the plasma flow velocity of this ionosphere is not well-constrained, but the close association with the rings suggests that its speed would be couppled to the keplarian velocity of the rings themselves. As a result, the motion of the plasma through Saturn's magnetic field would produce an induced voltage, oriented away from the planet outside synchronous orbit and towards the planet inside synchronous orbit. Such a potential could result in currents flowing across the ring plane and closeing along magnetic field lines and through Saturn's ionosphere at latitudes between 36o and 48o. Cassini observations of whistler-mode plasma wave emissions [Xin et al.,2006] centered on synchronous orbit (1.76 Rs, mapping to 41o latitude) have been interpreted as a product of field-aligned electron beams associated with such a current. This presentation will investigate the magnitude of these currents and the resulting Joule heating of the ionosphere. An important constraint is that no auroral ultraviolet emissions have been observed at the relevant latitudes. In contrast, Joule heating could affect infrared emissions from H3+. Variations in H3+ emission associated with Saturn's rings have been reported by O'Donoghue et al., 2013, and interpreted as a result of ring "rain", i.e. precipitating water group species from the rings which alter ionosphereic chemistry and H3+ densities. As noted by O'Donoghue et al., this interpretation may be

  17. GRISM Spectophotometry of the Uranus Ring

    Smith, Bradford


    Details of the near-infrared spectral reflectance of the Uranus rings are poorly known, because of problems associated with the scattered light from the planet. Grism spectroscopy of the brightest part of the Epsilon ring will be made with the planet just outside the field of view. To minimize the glare from Uranus, the observations should made when the widest part of the Epsilon ring is at a position angle of approximately 174 degrees. This is one in a series of observations designed to intercompare the near-infrared spectral reflectivity of dark objects in the solar system. Some record of processes that occurred within the Uranus subnebula may be left on the surfaces of the ring particles or the surface coatings of the associated dark inner satellites.

  18. Oligomeric ferrocene rings

    Inkpen, Michael S.; Scheerer, Stefan; Linseis, Michael; White, Andrew J. P.; Winter, Rainer F.; Albrecht, Tim; Long, Nicholas J.


    Cyclic oligomers comprising strongly interacting redox-active monomer units represent an unknown, yet highly desirable class of nanoscale materials. Here we describe the synthesis and properties of the first family of molecules belonging to this compound category—differently sized rings comprising only 1,1‧-disubstituted ferrocene units (cyclo[n], n = 5-7, 9). Due to the close proximity and connectivity of centres (covalent Cp-Cp linkages; Cp = cyclopentadienyl) solution voltammograms exhibit well-resolved, separated 1e- waves. Theoretical interrogations into correlations based on ring size and charge state are facilitated using values of the equilibrium potentials of these transitions, as well as their relative spacing. As the interaction free energies between the redox centres scale linearly with overall ring charge and in conjunction with fast intramolecular electron transfer (˜107 s-1), these molecules can be considered as uniformly charged nanorings (diameter ˜1-2 nm).

  19. Rings dominate western Gulf

    Vidal L., Francisco V.; Vidal L., Victor M. V.; Molero, José María Pérez

    Surface and deep circulation of the central and western Gulf of Mexico is controlled by interactions of rings of water pinched from the gulf's Loop Current. The discovery was made by Mexican oceanographers who are preparing a full-color, 8-volume oceanographic atlas of the gulf.Anticyclonic warm-core rings pinch off the Loop Current at a rate of about one to two per year, the scientists of the Grupo de Estudios Oceanográficos of the Instituto de Investigaciones Eléctricas (GEO-IIE) found. The rings migrate west until they collide with the continental shelf break of the western gulf, almost always between 22° and 23°N latitude. On their westward travel they transfer angular momentum and vorticity to the surrounding water, generating cyclonic circulations and vortex pairs that completely dominate the entire surface and deep circulation of the central and western gulf.

  20. Autocatalytic chemical smoke rings

    Rogers, M C; Rogers, Michael C.; Morris, Stephen W.


    Buoyant plumes, evolving free of boundary constraints, may develop well-defined mushroom shaped heads. In normal plumes, overturning flow in the head entrains less buoyant fluid from the surroundings as the head rises, robbing the plume of its driving force. We consider here a new type of plume in which the source of buoyancy is an autocatalytic chemical reaction. The reaction occurs at a sharp front which separates reactants from less dense products. In this type of plume, entrainment assists the reaction, producing new buoyancy which fuels an accelerating plume head. When the head has grown to a critical size, it detaches from the upwelling conduit, forming an accelerating, buoyant vortex ring. This vortex is analogous to a rising smoke ring. A second-generation head then develops at the point of detachment.Multiple generations of chemical vortex rings can detach from a single triggering event.