WorldWideScience

Sample records for right-lateral strike-slip focal

  1. Right-lateral shear and rotation as the explanation for strike-slip faulting in eastern Tibet

    Science.gov (United States)

    England, Philip; Molnar, Peter

    1990-01-01

    Bounds are placed here on the rate of rotation proposed by Cobbold and Davy (1988) for the major strike-slip faults in the eastern Tibetan Plateau. It is also concluded here that the image of lateral transport on such faults, known also as continental escape, extrusion, or expulsion, is an illusion, and that instead the left-lateral slip on east-striking plates in eastern Tibet is a manifestation of north-striking right-lateral simple shear. If this conclusion is correct, the east-striking left-lateral faults and the crustal blocks between them are rotating clockwise at 1-2 deg/Myr, the east-west dimension of eastern Tibet is shortening at 10-20 mm/yr, and little material is moving eastward out of India's path into Eursasia by left-lateral simple shear.

  2. THE ILICA BRANCH OF THE SOUTHEASTERN ESKIŞEHIR FAULT ZONE: AN ACTIVE RIGHT LATERAL STRIKE-SLIP STRUCTURE IN CENTRAL ANATOLIA, TURKEY

    Directory of Open Access Journals (Sweden)

    Korhan ESAT

    2016-12-01

    Full Text Available The Eskişehir Fault Zone is one of the prominent neotectonic structures of Turkey. It separates the west  Anatolian extensional province and the strike-slip induced northwest central Anatolian contractional area in the Anatolian Block. Its southeastern part is generally divided into three branches, namely the Ilıca, Yeniceoba, and Cihanbeyli from north to south, respectively. The right lateral strike-slip Ilıca branch (IB is an approximately 100-km-long fault and it is composed of several segments in a northwest-southeast direction. The slickensides, subsidiary fractures, cataclastic zone, fracture-controlled drainage pattern, right lateral stream deflections, deformation in the Quaternary unit observing in the seismic reflection sections, and seismicity of the region all indicate that the IB is an active right lateral strike-slip fault. The IB has also a regional tectonic importance as a boundary fault between the contractional and the extensional regions in central Anatolia considering that it is the southern limit of the contraction-related structures in the west-southwest of Ankara.

  3. Crimea-Kopet Dagh zone of concentrated orogenic deformations as a transregional late collisional right-lateral strike-slip fault

    Science.gov (United States)

    Patina, I. S.; Leonov, Yu. G.; Volozh, Yu. A.; Kopp, M. L.; Antipov, M. P.

    2017-07-01

    It is shown that the Crimea, Caucasus, and Kopet Dagh fold systems make up a single whole unified by a lithospheric strike-slip fault zone of concentrated dislocations. The strike-slip fault that dissects the sedimentary cover and consolidated crust is rooted in subcrustal layers of the mantle. The notions about strike-slip dislocations in the structure of the Crimea-Kopet Dagh System are considered. Comparative analysis of structure, age, and amplitude of strike-slip fault segments is carried out. The effect of strike-slip faulting on the deep-seated and near-surface structure of the Earth's crust is considered. Based on estimation of strike-slip offsets, the paleogeography of Paleogene basins is refined; their initial contours, which have been disturbed and fragmented by slipping motion strike-slip displacement, have been reconstructed.

  4. The 2014 Mw6.9 Gokceada and 2017 Mw6.3 Lesvos Earthquakes in the Northern Aegean Sea: The Transition from Right-Lateral Strike-Slip Faulting on the North Anatolian Fault to Extension in the Central Aegean

    Science.gov (United States)

    Cetin, S.; Konca, A. O.; Dogan, U.; Floyd, M.; Karabulut, H.; Ergintav, S.; Ganas, A.; Paradisis, D.; King, R. W.; Reilinger, R. E.

    2017-12-01

    The 2014 Mw6.9 Gokceada (strike-slip) and 2017 Mw6.3 Lesvos (normal) earthquakes represent two of the set of faults that accommodate the transition from right-lateral strike-slip faulting on the North Anatolian Fault (NAF) to normal faulting along the Gulf of Corinth. The Gokceada earthquake was a purely strike-slip event on the western extension of the NAF where it enters the northern Aegean Sea. The Lesvos earthquake, located roughly 200 km south of Gokceada, occurred on a WNW-ESE-striking normal fault. Both earthquakes respond to the same regional stress field, as indicated by their sub-parallel seismic tension axis and far-field coseismic GPS displacements. Interpretation of GPS-derived velocities, active faults, crustal seismicity, and earthquake focal mechanisms in the northern Aegean indicates that this pattern of complementary faulting, involving WNW-ESE-striking normal faults (e.g. Lesvos earthquake) and SW-NE-striking strike-slip faults (e.g. Gokceada earthquake), persists across the full extent of the northern Aegean Sea. The combination of these two "families" of faults, combined with some systems of conjugate left-lateral strike-slip faults, complement one another and culminate in the purely extensional rift structures that form the large Gulfs of Evvia and Corinth. In addition to being consistent with seismic and geodetic observations, these fault geometries explain the increasing velocity of the southern Aegean and Peloponnese regions towards the Hellenic subduction zone. Alignment of geodetic extension and seismic tension axes with motion of the southern Aegean towards the Hellenic subduction zone suggests a direct association of Aegean extension with subduction, possibly by trench retreat, as has been suggested by prior investigators.

  5. Combining Earthquake Focal Mechanism Inversion and Coulomb Friction Law to Yield Tectonic Stress Magnitudes in Strike-slip Faulting Regime

    Science.gov (United States)

    Soh, I.; Chang, C.

    2017-12-01

    The techniques for estimating present-day stress states by inverting multiple earthquake focal mechanism solutions (FMS) provide orientations of the three principal stresses and their relative magnitudes. In order to estimate absolute magnitudes of the stresses that are generally required to analyze faulting mechanics, we combine the relative stress magnitude parameter (R-value) derived from the inversion process and the concept of frictional equilibrium of stress state defined by Coulomb friction law. The stress inversion in Korean Peninsula using 152 FMS data (magnitude≥2.5) conducted at regularly spaced grid points yields a consistent strike-slip faulting regime in which the maximum (S1) and the minimum (S3) principal stresses act in horizontal planes (with an S1 azimuth in ENE-WSW) and the intermediate principal stress (S2) close to vertical. However, R-value varies from 0.28 to 0.75 depending on locations, systematically increasing eastward. Based on the assumptions that the vertical stress is lithostatic, pore pressure is hydrostatic, and the maximum differential stress (S1-S3) is limited by Byerlee's friction of optimally oriented faults for slip, we estimate absolute magnitudes of the two horizontal principal stresses using R-value. As R-value increases, so do the magnitudes of the horizontal stresses. Our estimation of the stress magnitudes shows that the maximum horizontal principal stress (S1) normalized by vertical stress tends to increase from 1.3 in the west to 1.8 in the east. The estimated variation of stress magnitudes is compatible with distinct clustering of faulting types in different regions. Normal faulting events are densely populated in the west region where the horizontal stress is relatively low, whereas numerous reverse faulting events prevail in the east offshore where the horizontal stress is relatively high. Such a characteristic distribution of distinct faulting types in different regions can only be explained in terms of stress

  6. The significance of strike-slip faulting in the basement of the Zagros fold and thrust belt

    Energy Technology Data Exchange (ETDEWEB)

    Hessami, K.; Koyi, H.A.; Talbot, C.J. [Uppsala University (Sweden). Institute of Earth Sciences

    2000-01-01

    Lateral offsets in the pattern of seismicity along the Zagros fold and thrust belt indicate that transverse faults segmenting the Arabian basement are active deep-seated strike-slip faults. The dominant NW-SE trending features of the belt have undergone repeated horizontal displacements along these transverse faults. These reactivated basement faults, which are inherited from the Pan-African construction phase, controlled both deposition of the Phanerozoic cover before Tertiary-Recent deformation of the Zagros and probably the entrapment of hydrocarbons on the NE margin of Arabia and in the Zagros area. We have used observations of faulting recognized on Landsat satellite images, in conjunction with the spatial distribution of earthquakes and their focal mechanism solutions, to infer a tectonic model for the Zagros basement. Deformation in the NW Zagros appears to be concentrated on basement thrusts and a few widely-spaced north-south trending strike-slip faults which separate major structural segments. In the SE Zagros, two main structural domains can be distinguished. A domain of NNW-trending right-lateral faults in the northern part of the SE Zagros implies that fault-bounded blocks are likely to have rotated anticlockwise about vertical axes relative to both Arabia and Central Iran. In contrast, the predominance of NNE-trending left-lateral faults in the southern part of the SE Zagros implies that fault-bounded blocks may have rotated clockwise about vertical axes. We propose a tectonic model in which crustal blocks bounded by strike-slip faults in a zone of simple shear rotate about vertical axes relative to both Arabia and Central Iran. The presence of domains of strike-slip and thrust faulting in the Zagros basement suggest that some of the convergence between Arabia and Central Iran is accommodated by rotation and possible lateral movement of crust along the belt by strike-slip faults, as well as by obvious crustal shortening and thickening along thrust

  7. The 2005 - 2007 Bala (Ankara, central Turkey) earthquakes: a case study for strike-slip fault terminations

    OpenAIRE

    Esat, K.; Çivgin, B.; Kaypak, B.; Isik, V.; Ecevitoglu, B.; Seyitoglu, G.

    2014-01-01

    An intense seismic activity has been observed after the Bala (Ankara, NW central Turkey) earthquakes (30 July 2005: Mw=5.3, 20 December 2007: Mw=5.4, and 26 December 2007: Mw=5.3), continuing up to the present. The epicenters and the focal mechanism solutions of the earthquakes indicate that the right lateral strike-slip Afşar fault, trending N55-60°W, is responsible for the main shocks. The Afşar fault is thought to be the NW continuation of the Tuzgölü fault zone, which is one of the main n...

  8. Active strike-slip faulting in El Salvador, Central America

    Science.gov (United States)

    Corti, Giacomo; Carminati, Eugenio; Mazzarini, Francesco; Oziel Garcia, Marvyn

    2005-12-01

    Several major earthquakes have affected El Salvador, Central America, during the Past 100 yr as a consequence of oblique subduction of the Cocos plate under the Caribbean plate, which is partitioned between trench-orthogonal compression and strike-slip deformation parallel to the volcanic arc. Focal mechanisms and the distribution of the most destructive earthquakes, together with geomorphologic evidence, suggest that this transcurrent component of motion may be accommodated by a major strike-slip fault (El Salvador fault zone). We present field geological, structural, and geomorphological data collected in central El Salvador that allow the constraint of the kinematics and the Quaternary activity of this major seismogenic strike-slip fault system. Data suggest that the El Salvador fault zone consists of at least two main ˜E-W fault segments (San Vicente and Berlin segments), with associated secondary synthetic (WNW-ESE) and antithetic (NNW-SSE) Riedel shears and NW-SE tensional structures. The two main fault segments overlap in a dextral en echelon style with the formation of an intervening pull-apart basin. Our original geological and geomorphologic data suggest a late Pleistocene Holocene slip rate of ˜11 mm/yr along the Berlin segment, in contrast with low historical seismicity. The kinematics and rates of deformation suggested by our new data are consistent with models involving slip partitioning during oblique subduction, and support the notion that a trench-parallel component of motion between the Caribbean and Cocos plates is concentrated along E-W dextral strike-slip faults parallel to the volcanic arc.

  9. Strike-slip faults offshore southern Taiwan: implications for the oblique arc-continent collision processes

    Science.gov (United States)

    Fuh, Shi-Chie; Liu, Char-Shine; Lundberg, Neil; Reed, Donald L.

    1997-06-01

    Taiwan is the site of present-day oblique arc-continent collision between the Luzon arc of the Philippine Sea plate and the Chinese continental margin. The major structural pattern revealed from marine geophysical studies in the area offshore southern Taiwan is that of a doubly-vergent orogenic belt, bounded by significant zones of thrusting on the west and east of the submarine accretionary wedge. Due to the oblique collision process, strike-slip faults could play an important role in this convergent domain. Topographic lineaments revealed from new digital bathymetry data and seismic reflection profiles confirm the existence of three sets of strike-slip faults in the collision-subduction zone offshore southern Taiwan: the N-S-trending left-lateral strike-slip faults within the Luzon volcanic arc, the NE-SW-trending right-lateral strike-slip faults across the accretionary wedge, and the NNE-SSW-trending left-lateral strike-slip faults lie in the frontal portion of the accretionary wedge. These strike-slip faults overprint pre-existing folds and thrusts and may convert into oblique thrusts or thrusts as the forearc blocks accrete to the mountain belt. A bookshelf rotation model is used to explain the observed geometrical relationships of these strike-slip fault systems. Based on this model, the counter-clockwise rotation of the forearc blocks in the area offshore southern Taiwan could have caused extrusion of the accretionary wedge material into the forearc basin. The originally continuous forearc basin is thus deformed into several closed and separate proto-collisional basins such as the Southern Longitudinal Trough and Taitung Trough. A tectonic evolution model which emphasizes on the development of various structures at different stages of the oblique arc-continent collision for the Taiwan mountain belt is proposed.

  10. Strike-slip tectonics during rift linkage

    Science.gov (United States)

    Pagli, C.; Yun, S. H.; Ebinger, C.; Keir, D.; Wang, H.

    2017-12-01

    The kinematics of triple junction linkage and the initiation of transforms in magmatic rifts remain debated. Strain patterns from the Afar triple junction provide tests of current models of how rifts grow to link in area of incipient oceanic spreading. Here we present a combined analysis of seismicity, InSAR and GPS derived strain rate maps to reveal that the plate boundary deformation in Afar is accommodated primarily by extensional tectonics in the Red Sea and Gulf of Aden rifts, and does not require large rotations about vertical axes (bookshelf faulting). Additionally, models of stress changes and seismicity induced by recent dykes in one sector of the Afar triple junction provide poor fit to the observed strike-slip earthquakes. Instead we explain these patterns as rift-perpendicular shearing at the tips of spreading rifts where extensional strains terminate against less stretched lithosphere. Our results demonstrate that rift-perpendicular strike-slip faulting between rift segments achieves plate boundary linkage during incipient seafloor spreading.

  11. Shell Tectonics: A Mechanical Model for Strike-slip Displacement on Europa

    Science.gov (United States)

    Rhoden, Alyssa Rose; Wurman, Gilead; Huff, Eric M.; Manga, Michael; Hurford, Terry A.

    2012-01-01

    We introduce a new mechanical model for producing tidally-driven strike-slip displacement along preexisting faults on Europa, which we call shell tectonics. This model differs from previous models of strike-slip on icy satellites by incorporating a Coulomb failure criterion, approximating a viscoelastic rheology, determining the slip direction based on the gradient of the tidal shear stress rather than its sign, and quantitatively determining the net offset over many orbits. This model allows us to predict the direction of net displacement along faults and determine relative accumulation rate of displacement. To test the shell tectonics model, we generate global predictions of slip direction and compare them with the observed global pattern of strike-slip displacement on Europa in which left-lateral faults dominate far north of the equator, right-lateral faults dominate in the far south, and near-equatorial regions display a mixture of both types of faults. The shell tectonics model reproduces this global pattern. Incorporating a small obliquity into calculations of tidal stresses, which are used as inputs to the shell tectonics model, can also explain regional differences in strike-slip fault populations. We also discuss implications for fault azimuths, fault depth, and Europa's tectonic history.

  12. Strike-slip deformation reflects complex partitioning of strain in the Nankai Accretionary Prism (SE Japan)

    Science.gov (United States)

    Azevedo, Marco C.; Alves, Tiago M.; Fonseca, Paulo E.; Moore, Gregory F.

    2018-01-01

    Previous studies have suggested predominant extensional tectonics acting, at present, on the Nankai Accretionary Prism (NAP), and following a parallel direction to the convergence vector between the Philippine Sea and Amur Plates. However, a complex set of thrusts, pop-up structures, thrust anticlines and strike-slip faults is observed on seismic data in the outer wedge of the NAP, hinting at a complex strain distribution across SE Japan. Three-dimensional (3D) seismic data reveal three main families of faults: (1) NE-trending thrusts and back-thrusts; (2) NNW- to N-trending left-lateral strike-slip faults; and (3) WNW-trending to E-W right-lateral strike-slip faults. Such a fault pattern suggests that lateral slip, together with thrusting, are the two major styles of deformation operating in the outer wedge of the NAP. Both styles of deformation reflect a transpressional tectonic regime in which the maximum horizontal stress is geometrically close to the convergence vector. This work is relevant because it shows a progressive change from faults trending perpendicularly to the convergence vector, to a broader partitioning of strain in the form of thrusts and conjugate strike-slip faults. We suggest that similar families of faults exist within the inner wedge of the NAP, below the Kumano Basin, and control stress accumulation and strain accommodation in this latter region.

  13. What causes an icy fault to slip? Investigating strike-slip failure conditions on Ganymede at Dardanus and Tiamat Sulcus.

    Science.gov (United States)

    Cameron, M. E.; Smith-Konter, B. R.; Burkhard, L. M.; Collins, G. C.; Seifert, F.; Pappalardo, R. T.

    2015-12-01

    Ganymede exhibits two geologically distinct terrains known as dark and light (grooved) terrain. The mechanism for a transition from dark to light terrain remains unclear; however, inferences of strike-slip faulting and distributed shear zones suggest that strike-slip tectonism may be important to the structural development of Ganymede's surface and in this transition. Here we investigate the role of tidal stresses on Ganymede in the formation and evolution of strike-slip structures in both dark and grooved terrains. Using numerical code SatStress, we calculate both diurnal and non-synchronous rotation (NSR) tidal stresses at Ganymede's surface. Specifically, we investigate the role of fault friction and orbital eccentricity in the development of ~45 km of right-lateral offset at Dardanus Sulcus and a possible case of study with a detailed morphological mapping of strike-slip morphologies (en echelon structures, strike-slip duplexes, laterally offset pre-existing features, and possible strained craters) at Nun Sulcus and several other locations. These structures serve as example regions to provide improved constraints for global stress mechanisms responsible for strike-slip fault evolution on Ganymede.

  14. Assemblage of strike-slip faults and tectonic extension and ...

    Indian Academy of Sciences (India)

    12

    the formation, evolution and distribution of these strike-slip faults have important. 80 ...... function of coal-derived gas study for natural gas industry development in China; .... Bohai-Zhangjiakou seismotectonic zone based on 3D visco-elastic ...

  15. Onset of aseismic creep on major strike-slip faults

    KAUST Repository

    Ç akir, Ziyadin; Ergintav, Semih; Ö zener, Haluk; Doǧan, Uǧur; Akoglu, Ahmet; Meghraoui, Mustapha; Reilinger, Robert E.

    2012-01-01

    Time series analysis of spaceborne synthetic aperture radar (SAR) data, GPS measurements, and fi eld observations reveal that the central section of the Izmit (Turkey) fault that slipped with a supershear rupture velocity in the A.D. 1999, Mw7.4, Izmit earthquake began creeping aseismically following the earthquake. Rapid initial postseismic afterslip decayed logarithmically with time and appears to have reached a steady rate comparable to the preearthquake full fault-crossing rate, suggesting that it may continue for decades and possibly until late in the earthquake cycle. If confi rmed by future monitoring, these observations identify postseismic afterslip as a mechanism for initiating creep behavior along strike-slip faults. Long-term afterslip and/or creep has signifi cant implications for earthquake cycle models, recurrence intervals of large earthquakes, and accordingly, seismic hazard estimation along mature strike-slip faults, in particular for Istanbul which is believed to lie adjacent to a seismic gap along the North Anatolian fault in the Sea of Marmara. © 2012 Geological Society of America.

  16. Onset of aseismic creep on major strike-slip faults

    KAUST Repository

    Çakir, Ziyadin

    2012-10-02

    Time series analysis of spaceborne synthetic aperture radar (SAR) data, GPS measurements, and fi eld observations reveal that the central section of the Izmit (Turkey) fault that slipped with a supershear rupture velocity in the A.D. 1999, Mw7.4, Izmit earthquake began creeping aseismically following the earthquake. Rapid initial postseismic afterslip decayed logarithmically with time and appears to have reached a steady rate comparable to the preearthquake full fault-crossing rate, suggesting that it may continue for decades and possibly until late in the earthquake cycle. If confi rmed by future monitoring, these observations identify postseismic afterslip as a mechanism for initiating creep behavior along strike-slip faults. Long-term afterslip and/or creep has signifi cant implications for earthquake cycle models, recurrence intervals of large earthquakes, and accordingly, seismic hazard estimation along mature strike-slip faults, in particular for Istanbul which is believed to lie adjacent to a seismic gap along the North Anatolian fault in the Sea of Marmara. © 2012 Geological Society of America.

  17. Magma storage in a strike-slip caldera.

    Science.gov (United States)

    Saxby, J; Gottsmann, J; Cashman, K; Gutiérrez, E

    2016-07-22

    Silicic calderas form during explosive volcanic eruptions when magma withdrawal triggers collapse along bounding faults. The nature of specific interactions between magmatism and tectonism in caldera-forming systems is, however, unclear. Regional stress patterns may control the location and geometry of magma reservoirs, which in turn may control the spatial and temporal development of faults. Here we provide new insight into strike-slip volcano-tectonic relations by analysing Bouguer gravity data from Ilopango caldera, El Salvador, which has a long history of catastrophic explosive eruptions. The observed low gravity beneath the caldera is aligned along the principal horizontal stress orientations of the El Salvador Fault Zone. Data inversion shows that the causative low-density structure extends to ca. 6 km depth, which we interpret as a shallow plumbing system comprising a fractured hydrothermal reservoir overlying a magmatic reservoir with vol% exsolved vapour. Fault-controlled localization of magma constrains potential vent locations for future eruptions.

  18. San Andreas-sized Strike-slip Fault on Europa

    Science.gov (United States)

    1998-01-01

    This mosaic of the south polar region of Jupiter's moon Europa shows the northern 290 kilometers (180 miles) of a strike-slip fault named Astypalaea Linea. The entire fault is about 810 kilometers (500 miles) long, about the size of the California portion of the San Andreas fault, which runs from the California-Mexico border north to the San Francisco Bay. In a strike-slip fault, two crustal blocks move horizontally past one another, similar to two opposing lanes of traffic. Overall motion along the fault seems to have followed a continuous narrow crack along the feature's entire length, with a path resembling steps on a staircase crossing zones that have been pulled apart. The images show that about 50 kilometers (30 miles) of displacement have taken place along the fault. The fault's opposite sides can be reconstructed like a puzzle, matching the shape of the sides and older, individual cracks and ridges broken by its movements. [figure removed for brevity, see original site] The red line marks the once active central crack of the fault. The black line outlines the fault zone, including material accumulated in the regions which have been pulled apart. Bends in the fault have allowed the surface to be pulled apart. This process created openings through which warmer, softer ice from below Europa's brittle ice shell surface, or frozen water from a possible subsurface ocean, could reach the surface. This upwelling of material formed large areas of new ice within the boundaries of the original fault. A similar pulling-apart phenomenon can be observed in the geological trough surrounding California's Salton Sea, in Death Valley and the Dead Sea. In those cases, the pulled-apart regions can include upwelled materials, but may be filled mostly by sedimentary and eroded material from above. One theory is that fault motion on Europa is induced by the pull of variable daily tides generated by Jupiter's gravitational tug on Europa. Tidal tension opens the fault and

  19. Origin and structure of major orogen-scale exhumed strike-slip

    Science.gov (United States)

    Cao, Shuyun; Neubauer, Franz

    2016-04-01

    The formation of major exhumed strike-slip faults represents one of the most important dynamic processes affecting the evolution of the Earth's lithosphere and surface. Detailed models of the potential initiation and properties and architecture of orogen-scale exhumed strike-slip faults and how these relate to exhumation are rare. In this study, we deal with key properties controlling the development of major exhumed strike-slip fault systems, which are equivalent to the deep crustal sections of active across fault zones. We also propose two dominant processes for the initiation of orogen-scale exhumed strike-slip faults: (1) pluton-controlled and (2) metamorphic core complex-controlled strike-slip faults. In these tectonic settings, the initiation of faults occurs by rheological weakening along hot-to-cool contacts and guides the overall displacement and ultimate exhumation. These processes result in a specific thermal and structural architecture of such faults. These types of strike-slip dominated fault zones are often subparallel to mountain ranges and expose a wide variety of mylonitic, cataclastic and non-cohesive fault rocks, which were formed at different structural levels of the crust during various stages of faulting. The high variety of distinctive fault rocks is a potential evidence for recognition of these types of strike-slip faults. Exhumation of mylonitic rocks is, therefore, a common feature of such reverse oblique-slip strike-slip faults, implying major transtensive and/or transpressive processes accompanying pure strike-slip motion during exhumation. Some orogen-scale strike-slip faults nucleate and initiate along rheologically weak zones, e.g. at granite intrusions, zones of low-strength minerals, thermally weakened crust due to ascending fluids, and lateral borders of hot metamorphic core complexes. A further mechanism is the juxtaposition of mechanically strong mantle lithosphere to hot asthenosphere in continental transform faults (e.g., San

  20. The 2012 Strike-slip Earthquake Sequence in Black Sea and its Link to the Caucasus Collision Zone

    Science.gov (United States)

    Tseng, T. L.; Hsu, C. H.; Legendre, C. P.; Jian, P. R.; Huang, B. S.; Karakhanian, A.; Chen, C. W.

    2016-12-01

    The Black Sea formed as a back-arc basin in Late Cretaceous to Paleogene with lots of extensional features. However, the Black Sea is now tectonically stable and absent of notable earthquakes except for the coastal region. In this study we invert regional waveforms of a new seismic array to constrain the focal mechanisms and depths of the 2012/12/23 earthquake sequence occurred in northeastern Black Sea basin that can provide unique estimates on the stress field in the region. The results show that the focal mechanisms for the main shock and 5 larger aftershocks are all strike-slip faulting and resembling with each other. The main rupture fall along the vertical dipping, NW-SE trending sinistral fault indicated by the lineation of most aftershocks. The fault strike and aftershock distribution are both consistent with the Shatsky Ridge, which is continental in nature but large normal faults was created by previous subsidence. The occurrence of 2012 earthquakes can be re-activated, as strike-slip, on one of the pre-existing normal fault cutting at depth nearly 20-30 km in the extended crust. Some of the aftershocks, including a larger one occurred 5 days later, are distributed toward NE direction 20 km away from main fault zone. Those events might be triggered by the main shock along a conjugate fault, which is surprisingly at the extension of proposed transform fault perpendicular to the rift axis of eastern Black Sea Basin. The focal mechanisms also indicate that the maximum compression in northeast Black Sea is at E-W direction, completely different from the N-S compression in the Caucasus and East Turkey controlled by Arabia-Eurasia collision. The origin of E-W maximum compression is probably the same as the secondary stress inferred from earthquakes in Racha region of the Greater Caucasus.

  1. The role of post-collisional strike-slip tectonics in the geological evolution of the late Neoproterozoic volcano-sedimentary Guaratubinha Basin, southern Brazil

    Science.gov (United States)

    Barão, Leonardo M.; Trzaskos, Barbara; Vesely, Fernando F.; de Castro, Luís Gustavo; Ferreira, Francisco J. F.; Vasconcellos, Eleonora M. G.; Barbosa, Tiago C.

    2017-12-01

    The Guaratubinha Basin is a late Neoproterozoic volcano-sedimentary basin included in the transitional-stage basins of the South American Platform. The aim of this study is to investigate its tectonic evolution through a detailed structural analysis based on remote sensing and field data. The structural and aerogeophysics data indicate that at least three major deformational events affected the basin. Event E1 caused the activation of the two main basin-bounding fault zones, the Guaratubinha Master Fault and the Guaricana Shear Zone. These structures, oriented N20-45E, are associated with well-defined right-lateral to oblique vertical faults, conjugate normal faults and vertical flow structures. Progressive transtensional deformation along the two main fault systems was the main mechanism for basin formation and the deposition of thick coarse-grained deposits close to basin-borders. The continuous opening of the basin provided intense intermediate and acid magmatism as well as deposition of volcaniclastic sediments. Event E2 characterizes generalized compression, recorded as minor thrust faults with tectonic transport toward the northwest and left-lateral activation of the NNE-SSW Palmital Shear Zone. Event E3 is related to the Mesozoic tectonism associated with the South Atlantic opening, which generated diabase dykes and predominantly right-lateral strike-slip faults oriented N10-50W. Its rhomboidal geometry with long axis parallel to major Precambrian shear zones, the main presence of high-angle, strike-slip or oblique faults, the asymmetric distribution of geological units and field evidence for concomitant Neoproterozoic magmatism and strike-slip movements are consistent with pull-apart basins reported in the literature.

  2. COMPARISON OF COSEISMIC IONOSPHERIC DISTURBANCE WAVEFORMS REVISITED: STRIKE-SLIP, NORMAL, AND REVERSE FAULT EARTHQUAKE

    Directory of Open Access Journals (Sweden)

    Mokhamad Nur Cahyadi

    2015-02-01

    Full Text Available Using Total Electron Content (TEC measurements with Global Positioning System we studied ionospheric responses to three large earthquakes with difference focal mechanism that occurred in the Sumatra Andaman 26 December 2004, North off Sumatra 11 April 2012, and North Japan 7 December 2012. These earthquakes have different focal mechanisms, i.e. high-angle reverse, strike-slip, and normal faulting, respectively. TEC responses to the Sumatra Andaman 2004 and north Japan 2012 events initiated with positive changes. On the other hand, the initial TEC changes in the Sumatra 2012 earthquake showed both positive and negative polarities depending on the azimuth around the focal area. Such a variety may reflect differences in coseismic vertical crustal displacements, which are dominated by uplift and subsidence in the Sumatra 2012 event. This phenomena has same characteristic with 1994 Kuril Arch earthquake. There are three different propagation velocity in the Sumatra 2012 earthquake, within the first 300 km until 430 km, the CID propagation velocity was ~3 km/s, which is equal to the secod sound speed at the height of the ionospheric F-layer. Starting from 380 km until 750 km out from the epicenter, the disturbance seems to divide into two separate perturbations, with each propagating at a different velocity, about 1 km/s for the one and about 0.4 m/s for the other. The apparent velocity in the Sumatra Andaman 2004 and Japan 2012 propagated ~ 1 km/s and ~ 0.3 km/s, consistent with the sound speed at the ionospheric F layer height and internal gravity wave respectively. Resonant oscillation of TEC with a frequency of ~ 3.7 mHZ and ~4.4 mHz have been found in the Sumatra 2012 and Sumatra Andaman 2004 events. Those earthquakes, which occurred during a period of quiet geomagnetic activity, also showed clear preseismic TEC anomalies similar to those before the 2011 Tohoku-Oki and 2007 Bengkulu earthquake.   The positive anomalies started 30-60 minutes

  3. Holocene paleoearthquakes on the strike-slip Porters Pass Fault, Canterbury, New Zealand

    International Nuclear Information System (INIS)

    Howard, M.; Nicol, A.; Campbell, J.; Pettinga, J.R.

    2005-01-01

    The Porters Pass Fault comprises a series of discontinuous Holocene active traces which extend for c. 40 km between the Rakaia and Waimakariri Rivers in the foothills of the Southern Alps. There have been no historical earthquakes on the Porters Pass Fault (i.e., within the last 150 yr), and the purpose of this paper is to establish the timing and magnitudes of displacements on the fault at the ground surface during Holocene paleoearthquakes. Displaced geomorphic features (e.g., relict streams, stream channels, and ridge crests), measured using either tape measure (n = 20) or surveying equipment (n = 5), range from 5.5 to 33 m right lateral strike slip and are consistent with six earthquakes characterised by slip per event of c. 5-7 m. The timing of these earthquakes is constrained by radiocarbon dates from four trenches excavated across the fault and two auger sites from within swamps produced by ponding of drainage along the fault scarp. These data indicate markedly different Holocene earthquake histories along the fault length separated by a behavioural segment boundary near Lake Coleridge. On the eastern segment at least six Holocene earthquakes were identified at 8400-9000, 5700-6700, 4500-6000, 2300-2500, 800-1100, and 500-600 yr BP, producing an average recurrence interval of c. 1500 yr. On the western segment of the fault in the Rakaia River valley, a single surface-rupturing earthquake displaced Acheron Advance glacial deposits (c.10,000-14,000 yr in age) and may represent the southward continuation of the 2300-2500 yr event identified on the eastern segment. These data suggest Holocene slip rates of 3.2-4.1 mm/yr and 0.3-0.9 mm/yr on the eastern and western sections of the fault, respectively. Displacement and timing data suggest that earthquakes ruptured the western segment of the fault in no more than one-sixth of cases and that for a sample period of 10,000 yr the recurrence intervals were not characteristic. (auth). 45 refs., 10 figs., 3 tabs

  4. The rupture process of the Manjil, Iran earthquake of 20 june 1990 and implications for intraplate strike-slip earthquakes

    Science.gov (United States)

    Choy, G.L.; Zednik, J.

    1997-01-01

    In terms of seismically radiated energy or moment release, the earthquake of 20 January 1990 in the Manjil Basin-Alborz Mountain region of Iran is the second largest strike-slip earthquake to have occurred in an intracontinental setting in the past decade. It caused enormous loss of life and the virtual destruction of several cities. Despite a very large meizoseismal area, the identification of the causative faults has been hampered by the lack of reliable earthquake locations and conflicting field reports of surface displacement. Using broadband data from global networks of digitally recording seismographs, we analyse broadband seismic waveforms to derive characteristics of the rupture process. Complexities in waveforms generated by the earthquake indicate that the main shock consisted of a tiny precursory subevent followed in the next 20 seconds by a series of four major subevents with depths ranging from 10 to 15 km. The focal mechanisms of the major subevents, which are predominantly strike-slip, have a common nodal plane striking about 285??-295??. Based on the coincidence of this strike with the dominant tectonic fabric of the region we presume that the EW striking planes are the fault planes. The first major subevent nucleated slightly south of the initial precursor. The second subevent occurred northwest of the initial precursor. The last two subevents moved progressively southeastward of the first subevent in a direction collinear with the predominant strike of the fault planes. The offsets in the relative locations and the temporal delays of the rupture subevents indicate heterogeneous distribution of fracture strength and the involvement of multiple faults. The spatial distribution of teleseismic aftershocks, which at first appears uncorrelated with meizoseismal contours, can be decomposed into stages. The initial activity, being within and on the periphery of the rupture zone, correlates in shape and length with meizoseismal lines. In the second stage

  5. High tsunami frequency as a result of combined strike-slip faulting and coastal landslides

    Science.gov (United States)

    Hornbach, Matthew J.; Braudy, Nicole; Briggs, Richard W.; Cormier, Marie-Helene; Davis, Marcy B.; Diebold, John B.; Dieudonne, Nicole; Douilly, Roby; Frohlich, Cliff; Gulick, Sean P.S.; Johnson, Harold E.; Mann, Paul; McHugh, Cecilia; Ryan-Mishkin, Katherine; Prentice, Carol S.; Seeber, Leonardo; Sorlien, Christopher C.; Steckler, Michael S.; Symithe, Steeve Julien; Taylor, Frederick W.; Templeton, John

    2010-01-01

    Earthquakes on strike-slip faults can produce devastating natural hazards. However, because they consist predominantly of lateral motion, these faults are rarely associated with significant uplift or tsunami generation. And although submarine slides can generate tsunami, only a few per cent of all tsunami are believed to be triggered in this way. The 12 January Mw 7.0 Haiti earthquake exhibited primarily strike-slip motion but nevertheless generated a tsunami. Here we present data from a comprehensive field survey that covered the onshore and offshore area around the epicentre to document that modest uplift together with slope failure caused tsunamigenesis. Submarine landslides caused the most severe tsunami locally. Our analysis suggests that slide-generated tsunami occur an order-of-magnitude more frequently along the Gonave microplate than global estimates predict. Uplift was generated because of the earthquake's location, where the Caribbean and Gonave microplates collide obliquely. The earthquake also caused liquefaction at several river deltas that prograde rapidly and are prone to failure. We conclude that coastal strike-slip fault systems such as the Enriquillo-Plantain Garden fault produce relief conducive to rapid sedimentation, erosion and slope failure, so that even modest predominantly strike-slip earthquakes can cause potentially catastrophic slide-generated tsunami - a risk that is underestimated at present.

  6. A note on 2-D lithospheric deformation due to a blind strike-slip fault

    Indian Academy of Sciences (India)

    mic deformation. Several researchers have devel- oped models of coseismic lithospheric deformation. Rybicki (1971) found a closed-form analytical solu- tion for the problem of a long vertical strike-slip fault in a two-layer model of the earth. Chinnery and Jovanovich (1972) extended the solution to a three-layer model.

  7. Carpathian Shear Corridor – A strike-slip boundary of an extruded crustal segment

    Czech Academy of Sciences Publication Activity Database

    Marko, F.; Andriessen, P.A.M.; Tomek, Č.; Bezák, V.; Fojtíková, Lucia; Bošanský, M.; Piovarči, M.; Reichenwalder, P.

    703-704, APR 22 (2017), s. 119-134 ISSN 0040-1951 Grant - others:Slovak Foundation Grant(SK) VEGA 2/0188/15 Institutional support: RVO:67985891 Keywords : extrusion * Neo-alpine evolution * strike-slip faulting * uplift history * Western Carpathians Subject RIV: DC - Siesmology, Volcanology, Earth Structure OBOR OECD: Geology Impact factor: 2.693, year: 2016

  8. The Role of Near-Fault Relief in Creating and Maintaining Strike-Slip Landscape Features

    Science.gov (United States)

    Harbert, S.; Duvall, A. R.; Tucker, G. E.

    2016-12-01

    Geomorphic landforms, such as shutter ridges, offset river terraces, and deflected stream channels, are often used to assess the activity and slip rates of strike-slip faults. However, in some systems, such as parts of the Marlborough Fault System (South Island, NZ), an active strike-slip fault does not leave a strong landscape signature. Here we explore the factors that dampen or enhance the landscape signature of strike-slip faulting using the Channel-Hillslope Integrated Landscape Development model (CHILD). We focus on variables affecting the length of channel offsets, which enhance the signature of strike-slip motion, and the frequency of stream captures, which eliminate offsets and reduce this signature. We model a strike-slip fault that passes through a mountain ridge, offsetting streams that drain across this fault. We use this setup to test the response of channel offset length and capture frequency to fault characteristics, such as slip rate and ratio of lateral to vertical motion, and to landscape characteristics, such as relief contrasts controlled by erodibility. Our experiments show that relief downhill of the fault, whether generated by differential uplift across the fault or by an erodibility contrast, has the strongest effect on offset length and capture frequency. This relief creates shutter ridges, which block and divert streams while being advected along a fault. Shutter ridges and the streams they divert have long been recognized as markers of strike-slip motion. Our results show specifically that the height of shutter ridges is most responsible for the degree to which they create long channel offsets by preventing stream captures. We compare these results to landscape metrics in the Marlborough Fault System, where shutter ridges are common and often lithologically controlled. We compare shutter ridge length and height to channel offset length in order to assess the influence of relief on offset channel features in a real landscape. Based on our

  9. Strike-slip tectonics and Quaternary basin formation along the Vienna Basin fault system inferred from Bouguer gravity derivatives

    NARCIS (Netherlands)

    Salcher, B. C.; Meurers, B.; Smit, J.; Decker, K.; HöLzel, M.; Wagreich, M.

    2012-01-01

    The Vienna Basin at the transition between the Alpine and Carpathian belt hosts a number of large Pleistocene sub-basins forming along an active continental scale strike-slip fault (Vienna Basin strike-slip fault). We utilize first-order derivatives from industrial Bouguer gravity data to unravel

  10. Timing of metamorphism of the Lansang gneiss and implications for left-lateral motion along the Mae Ping (Wang Chao) strike-slip fault, Thailand

    Science.gov (United States)

    Palin, R. M.; Searle, M. P.; Morley, C. K.; Charusiri, P.; Horstwood, M. S. A.; Roberts, N. M. W.

    2013-10-01

    The Mae Ping fault (MPF), western Thailand, exhibits dominantly left-lateral strike-slip motion and stretches for >600 km, reportedly branching off the right-lateral Sagaing fault in Myanmar and extending southeast towards Cambodia. Previous studies have suggested that the fault assisted the large-scale extrusion of Sundaland that occurred during the Late Eocene-Early Oligocene, with a geological offset of ˜120-150 km estimated from displaced high-grade gneisses and granites of the Chiang Mai-Lincang belt. Exposures of high-grade orthogneiss in the Lansang National Park, part of this belt, locally contain strong mylonitic textures and are bounded by strike-slip ductile shear zones and brittle faults. Geochronological analysis of monazite from a sample of sheared biotite-K-feldspar orthogneiss suggests two episodes of crystallization, with core regions documenting Th-Pb ages between c. 123 and c. 114 Ma and rim regions documenting a significantly younger age range between c. 45-37 Ma. These data are interpreted to represent possible magmatic protolith emplacement for the Lansang orthogneiss during the Early Cretaceous, with a later episode of metamorphism occurring during the Eocene. Textural relationships provided by in situ analysis suggest that ductile shearing along the MPF occurred during the latter stages of, or after, this metamorphic event. In addition, monazite analyzed from an undeformed garnet-two-mica granite dyke intruding metamorphic units at Bhumipol Lake outside of the Mae Ping shear zone produced a Th-Pb age of 66.2 ± 1.6 Ma. This age is interpreted to date the timing of dyke emplacement, implying that the MPF cuts through earlier formed magmatic and high-grade metamorphic rocks. These new data, when combined with regional mapping and earlier geochronological work, show that neither metamorphism, nor regional cooling, was directly related to strike-slip motion.

  11. Structure of the Melajo clay near Arima, Trinidad and strike-slip motion in the El Pilar fault zone

    Science.gov (United States)

    Robertson, P.; Burke, K.; Wadge, G.

    1985-01-01

    No consensus has yet emerged on the sense, timing and amount of motion in the El Pilar fault zone. As a contribution to the study of this problem, a critical area within the zone in North Central Trinidad has been mapped. On the basis of the mapping, it is concluded that the El Pilar zone has been active in right-lateral strike-slip motion during the Pleistocene. Recognition of structural styles akin to those of the mapped area leads to the suggestion that the El Pilar zone is part of a 300 km wide plate boundary zone extending from the Orinoco delta northward to Grenada. Lateral motion of the Caribbean plate with respect to South America has been suggested to amount to 1900 km in the last 38 Ma. Part of this displacement since the Miocene can be readily accommodated within the broad zone identified here. No one fault system need account for more than a fraction of the total motion and all faults need not be active simultaneously.

  12. Finite element models of earthquake cycles in mature strike-slip fault zones

    Science.gov (United States)

    Lynch, John Charles

    The research presented in this dissertation is on the subject of strike-slip earthquakes and the stresses that build and release in the Earth's crust during earthquake cycles. Numerical models of these cycles in a layered elastic/viscoelastic crust are produced using the finite element method. A fault that alternately sticks and slips poses a particularly challenging problem for numerical implementation, and a new contact element dubbed the "Velcro" element was developed to address this problem (Appendix A). Additionally, the finite element code used in this study was bench-marked against analytical solutions for some simplified problems (Chapter 2), and the resolving power was tested for the fault region of the models (Appendix B). With the modeling method thus developed, there are two main questions posed. First, in Chapter 3, the effect of a finite-width shear zone is considered. By defining a viscoelastic shear zone beneath a periodically slipping fault, it is found that shear stress concentrates at the edges of the shear zone and thus causes the stress tensor to rotate into non-Andersonian orientations. Several methods are used to examine the stress patterns, including the plunge angles of the principal stresses and a new method that plots the stress tensor in a manner analogous to seismic focal mechanism diagrams. In Chapter 4, a simple San Andreas-like model is constructed, consisting of two great earthquake producing faults separated by a freely-slipping shorter fault. The model inputs of lower crustal viscosity, fault separation distance, and relative breaking strengths are examined for their effect on fault communication. It is found that with a lower crustal viscosity of 1018 Pa s (in the lower range of estimates for California), the two faults tend to synchronize their earthquake cycles, even in the cases where the faults have asymmetric breaking strengths. These models imply that postseismic stress transfer over hundreds of kilometers may play a

  13. Rheological structure of the lithosphere in plate boundary strike-slip fault zones

    Science.gov (United States)

    Chatzaras, Vasileios; Tikoff, Basil; Kruckenberg, Seth C.; Newman, Julie; Titus, Sarah J.; Withers, Anthony C.; Drury, Martyn R.

    2016-04-01

    How well constrained is the rheological structure of the lithosphere in plate boundary strike-slip fault systems? Further, how do lithospheric layers, with rheologically distinct behaviors, interact within the strike-slip fault zones? To address these questions, we present rheological observations from the mantle sections of two lithospheric-scale, strike-slip fault zones. Xenoliths from ˜40 km depth (970-1100 ° C) beneath the San Andreas fault system (SAF) provide critical constraints on the mechanical stratification of the lithosphere in this continental transform fault. Samples from the Bogota Peninsula shear zone (BPSZ, New Caledonia), which is an exhumed oceanic transform fault, provide insights on lateral variations in mantle strength and viscosity across the fault zone at a depth corresponding to deformation temperatures of ˜900 ° C. Olivine recrystallized grain size piezometry suggests that the shear stress in the SAF upper mantle is 5-9 MPa and in the BPSZ is 4-10 MPa. Thus, the mantle strength in both fault zones is comparable to the crustal strength (˜10 MPa) of seismogenic strike-slip faults in the SAF system. Across the BPSZ, shear stress increases from 4 MPa in the surrounding rocks to 10 MPa in the mylonites, which comprise the core of the shear zone. Further, the BPSZ is characterized by at least one order of magnitude difference in the viscosity between the mylonites (1018 Paṡs) and the surrounding rocks (1019 Paṡs). Mantle viscosity in both the BPSZ mylonites and the SAF (7.0ṡ1018-3.1ṡ1020 Paṡs) is relatively low. To explain our observations from these two strike-slip fault zones, we propose the "lithospheric feedback" model in which the upper crust and lithospheric mantle act together as an integrated system. Mantle flow controls displacement and the upper crust controls the stress magnitude in the system. Our stress data combined with data that are now available for the middle and lower crustal sections of other transcurrent fault

  14. The cenozoic strike-slip faults and TTHE regional crust stability of Beishan area

    International Nuclear Information System (INIS)

    Guo Zhaojie; Zhang Zhicheng; Zhang Chen; Liu Chang; Zhang Yu; Wang Ju; Chen Weiming

    2008-01-01

    The remote sensing images and geological features of Beishan area indicate that the Altyn Tagh fault, Sanweishan-Shuangta fault, Daquan fault and Hongliuhe fault are distributed in Beishan area from south to north. The faults are all left-lateral strike-slip faults with trending of NE40-50°, displaying similar distribution pattern. The secondary branch faults are developed at the end of each main strike-slip fault with nearly east to west trending form dendritic oblique crossings at the angle of 30-50°. Because of the left-lateral slip of the branch faults, the granites or the blocks exposed within the branch faults rotate clockwisely, forming 'Domino' structures. So the structural style of Beishan area consists of the Altyn Tagh fault, Sanweishan-Shuangta fault, Daquan fault, Hongliuhe fault and their branch faults and rotational structures between different faults. Sedimentary analysis on the fault valleys in the study area and ESR chronological test of fault clay exhibit that the Sanweishan-Shuangta fault form in the late Pliocene (N2), while the Daquan fault displays formation age of l.5-1.2 Ma, and the activity age of the relevant branch faults is Late Pleistocene (400 ka). The ages become younger from the Altyn Tagh fault to the Daquan fault and strike-slip faults display NW trending extension, further revealing the lateral growth process of the strike-slip boundary at the northern margin during the Cenozoic uplift of Tibetan Plateau. The displacement amounts on several secondary faults caused by the activities of the faults are slight due to the above-mentioned structural distribution characteristics of Beishan area, which means that this area is the most stable active area with few seismic activities. We propose the main granitic bodies in Beishan area could be favorable preselected locations for China's high level radioactive waste repository. (authors)

  15. A note on 2-D lithospheric deformation due to a blind strike-slip fault

    Indian Academy of Sciences (India)

    Analytical solution for the problem of a surface-breaking long strike-slip fault in an elastic layer overlying an elastic half-space is well known. The purpose of this note is to obtain the corresponding solution for a blind fault. Since the solution is valid for arbitrary values of the fault-depth and the dip angle, the effects of these ...

  16. The morphology of strike-slip faults - Examples from the San Andreas Fault, California

    Science.gov (United States)

    Bilham, Roger; King, Geoffrey

    1989-01-01

    The dilatational strains associated with vertical faults embedded in a horizontal plate are examined in the framework of fault kinematics and simple displacement boundary conditions. Using boundary element methods, a sequence of examples of dilatational strain fields associated with commonly occurring strike-slip fault zone features (bends, offsets, finite rupture lengths, and nonuniform slip distributions) is derived. The combinations of these strain fields are then used to examine the Parkfield region of the San Andreas fault system in central California.

  17. Evolution of strike-slip fault systems and associated geomorphic structures. Model test

    International Nuclear Information System (INIS)

    Ueta, Keichi

    2003-01-01

    Sandbox experiments were performed to investigate evolution of fault systems and its associated geomorphic structures caused by strike-slip motion on basement faults. A 200 cm long, 40 cm wide, 25 cm high sandbox was used in a strike-slip fault model test. Computerized X-ray tomography applied to the sandbox experiments made it possible to analyze the kinematic evaluation, as well as the three-dimensional geometry, of the faults. The deformation of the sand pack surface was analyzed by use of a laser method 3D scanner, which is a three-dimensional noncontact surface profiling instrument. A comparison of the experimental results with natural cases of active faults reveals the following: In the left-lateral strike-slip fault experiments, the deformation of the sand pack with increasing basement displacement is observed as follows. 1) In three dimensions, the right-stepping shears that have a cirque'/'shell'/'shipbody' shape develop on both sides of the basement fault. The shears on one side of the basement fault join those on the other side, resulting in helicoidal shaped shear surfaces. Shears reach the surface of the sand near or above the basement fault and en echelon Riedel shears are observed at the surface of the sand. The region between two Riedels is always an up-squeezed block. 2) lower-angle shears generally branch off from the first Riedel shears. 3) Pressure ridges develop within the zone defined by the right-stepping helicoidal shaped lower-angle shears. 4) Grabens develop between the pressure ridges. 5) Y-shears offset the pressure ridges. 6) With displacement concentrated on the central throughgoing fault zone, a liner trough developed directly above the basement fault. R1 shear and P foliation are observed in the liner trough. Such evolution of the shears and its associated structures in the fault model tests agrees well with that of strike-slip fault systems and its associated geomorphic structures. (author)

  18. Characterization of Aftershock Sequences from Large Strike-Slip Earthquakes Along Geometrically Complex Faults

    Science.gov (United States)

    Sexton, E.; Thomas, A.; Delbridge, B. G.

    2017-12-01

    Large earthquakes often exhibit complex slip distributions and occur along non-planar fault geometries, resulting in variable stress changes throughout the region of the fault hosting aftershocks. To better discern the role of geometric discontinuities on aftershock sequences, we compare areas of enhanced and reduced Coulomb failure stress and mean stress for systematic differences in the time dependence and productivity of these aftershock sequences. In strike-slip faults, releasing structures, including stepovers and bends, experience an increase in both Coulomb failure stress and mean stress during an earthquake, promoting fluid diffusion into the region and further failure. Conversely, Coulomb failure stress and mean stress decrease in restraining bends and stepovers in strike-slip faults, and fluids diffuse away from these areas, discouraging failure. We examine spatial differences in seismicity patterns along structurally complex strike-slip faults which have hosted large earthquakes, such as the 1992 Mw 7.3 Landers, the 2010 Mw 7.2 El-Mayor Cucapah, the 2014 Mw 6.0 South Napa, and the 2016 Mw 7.0 Kumamoto events. We characterize the behavior of these aftershock sequences with the Epidemic Type Aftershock-Sequence Model (ETAS). In this statistical model, the total occurrence rate of aftershocks induced by an earthquake is λ(t) = λ_0 + \\sum_{i:t_i

  19. Magmatic control along a strike-slip volcanic arc: The central Aeolian arc (Italy)

    Science.gov (United States)

    Ruch, J.; Vezzoli, L.; De Rosa, R.; Di Lorenzo, R.; Acocella, V.

    2016-02-01

    The regional stress field in volcanic areas may be overprinted by that produced by magmatic activity, promoting volcanism and faulting. In particular, in strike-slip settings, the definition of the relationships between the regional stress field and magmatic activity remains elusive. To better understand these relationships, we collected stratigraphic, volcanic, and structural field data along the strike-slip central Aeolian arc (Italy): here the islands of Lipari and Vulcano separate the extensional portion of the arc (to the east) from the contractional one (to the west). We collected >500 measurements of faults, extension fractures, and dikes at 40 sites. Most structures are NNE-SSW to NNW-SSE oriented, eastward dipping, and show almost pure dip-slip motion, consistent with an E-W extension direction, with minor dextral and sinistral shear. Our data highlight six eruptive periods during the last 55 ka, which allow considering both islands as a single magmatic system, in which tectonic and magmatic activities steadily migrated eastward and currently focus on a 10 km long × 2 km wide active segment. Faulting appears to mostly occur in temporal and spatial relation with magmatic events, supporting that most of the observable deformation derives from transient magmatic activity (shorter term, days to months), rather than from steady longer-term regional tectonics (102-104 years). More in general, the central Aeolian case shows how magmatic activity may affect the structure and evolution of volcanic arcs, overprinting any strike-slip motion with magma-induced extension at the surface.

  20. Magmatic control along a strike-slip volcanic arc: The central Aeolian arc (Italy)

    KAUST Repository

    Ruch, Joel

    2016-01-23

    The regional stress field in volcanic areas may be overprinted by that produced by magmatic activity, promoting volcanism and faulting. In particular, in strike-slip settings, the definition of the relationships between the regional stress field and magmatic activity remains elusive. To better understand these relationships, we collected stratigraphic, volcanic and structural field data along the strike-slip Central Aeolian arc (Italy): here the islands of Lipari and Vulcano separate the extensional portion of the arc (to the east) from the contractional one (to the west). We collected >500 measurements of faults, extension fractures and dikes at 40 sites. Most structures are NNE-SSW to NNW-SSE oriented, eastward dipping, and show almost pure dip-slip motion; consistent with an E-W extension direction, with minor dextral and sinistral shear. Our data highlight six eruptive periods during the last 55 ka, which allow considering both islands as a single magmatic system, in which tectonic and magmatic activity steadily migrated eastward and currently focus on a 10 km long x 2 km wide active segment. Faulting appears to mostly occur in temporal and spatial relation with magmatic events, supporting that most of the observable deformation derives from transient magmatic activity (shorter-term, days to months), rather than from steady longer-term regional tectonics (102-104 years). More in general, the Central Aeolian case shows how magmatic activity may affect the structure and evolution of volcanic arcs, overprinting any strike-slip motion with magma-induced extension at the surface.

  1. Non-Andersonian conjugate strike-slip faults: Observations, theory, and tectonic implications

    International Nuclear Information System (INIS)

    Yin, A; Taylor, M H

    2008-01-01

    Formation of conjugate strike-slip faults is commonly explained by the Anderson fault theory, which predicts a X-shaped conjugate fault pattern with an intersection angle of ∼30 degrees between the maximum compressive stress and the faults. However, major conjugate faults in Cenozoic collisional orogens, such as the eastern Alps, western Mongolia, eastern Turkey, northern Iran, northeastern Afghanistan, and central Tibet, contradict the theory in that the conjugate faults exhibit a V-shaped geometry with intersection angles of 60-75 degrees, which is 30-45 degrees greater than that predicted by the Anderson fault theory. In Tibet and Mongolia, geologic observations can rule out bookshelf faulting, distributed deformation, and temporal changes in stress state as explanations for the abnormal fault patterns. Instead, the GPS-determined velocity field across the conjugate fault zones indicate that the fault formation may have been related to Hagen-Poiseuille flow in map view involving the upper crust and possibly the whole lithosphere based on upper mantle seismicity in southern Tibet and basaltic volcanism in Mongolia. Such flow is associated with two coeval and parallel shear zones having opposite shear sense; each shear zone produce a set of Riedel shears, respectively, and together the Riedel shears exhibit the observed non-Andersonian conjugate strike-slip fault pattern. We speculate that the Hagen-Poiseuille flow across the lithosphere that hosts the conjugate strike-slip zones was produced by basal shear traction related to asthenospheric flow, which moves parallel and away from the indented segment of the collisional fronts. The inferred asthenospheric flow pattern below the conjugate strike-slip fault zones is consistent with the magnitude and orientations of seismic anisotropy observed across the Tibetan and Mongolian conjugate fault zones, suggesting a strong coupling between lithospheric deformation and asthenospheric flow. The laterally moving

  2. Non-Andersonian conjugate strike-slip faults: Observations, theory, and tectonic implications

    Energy Technology Data Exchange (ETDEWEB)

    Yin, A [Department of Earth and Space Sciences and Institute of Geophysics and Planetary Physics, University of California, Los Angeles, Los Angeles, CA 90025-1567 (United States); Taylor, M H [Department of Geology, University of Kansas, 1475 Jayhawk Blvd., Lawrence, KS 66044 (United States)], E-mail: yin@ess.ucla.edu

    2008-07-01

    Formation of conjugate strike-slip faults is commonly explained by the Anderson fault theory, which predicts a X-shaped conjugate fault pattern with an intersection angle of {approx}30 degrees between the maximum compressive stress and the faults. However, major conjugate faults in Cenozoic collisional orogens, such as the eastern Alps, western Mongolia, eastern Turkey, northern Iran, northeastern Afghanistan, and central Tibet, contradict the theory in that the conjugate faults exhibit a V-shaped geometry with intersection angles of 60-75 degrees, which is 30-45 degrees greater than that predicted by the Anderson fault theory. In Tibet and Mongolia, geologic observations can rule out bookshelf faulting, distributed deformation, and temporal changes in stress state as explanations for the abnormal fault patterns. Instead, the GPS-determined velocity field across the conjugate fault zones indicate that the fault formation may have been related to Hagen-Poiseuille flow in map view involving the upper crust and possibly the whole lithosphere based on upper mantle seismicity in southern Tibet and basaltic volcanism in Mongolia. Such flow is associated with two coeval and parallel shear zones having opposite shear sense; each shear zone produce a set of Riedel shears, respectively, and together the Riedel shears exhibit the observed non-Andersonian conjugate strike-slip fault pattern. We speculate that the Hagen-Poiseuille flow across the lithosphere that hosts the conjugate strike-slip zones was produced by basal shear traction related to asthenospheric flow, which moves parallel and away from the indented segment of the collisional fronts. The inferred asthenospheric flow pattern below the conjugate strike-slip fault zones is consistent with the magnitude and orientations of seismic anisotropy observed across the Tibetan and Mongolian conjugate fault zones, suggesting a strong coupling between lithospheric deformation and asthenospheric flow. The laterally moving

  3. Source study of the Jan Mayen transform fault strike-slip earthquakes

    Science.gov (United States)

    Rodríguez-Pérez, Q.; Ottemöller, L.

    2014-07-01

    Seismic source parameters of oceanic transform zone earthquakes have been relatively poorly studied. Previous studies showed that this type of earthquakes has unique characteristics such as not only the relatively common occurrence of slow events with weak seismic radiation at high frequencies but also the occurrence of some events that have high apparent stress indicating strong high frequency radiation. We studied 5 strike-slip earthquakes in the Jan Mayen fracture zone with magnitudes in the range of 5.9 centroid time delay compared to other oceanic transform fault earthquakes.

  4. A recent Mw 4.3 earthquake proving activity of a shallow strike-slip fault in the northern part of the Western Desert, Egypt

    Science.gov (United States)

    Ezzelarab, Mohamed; Ebraheem, Mohamed O.; Zahradník, Jiří

    2018-03-01

    The Mw 4.3 earthquake of September 2015 is the first felt earthquake since 1900 A.D in the northern part of the Western Desert, Egypt, south of the El-Alamein City. The available waveform data observed at epicentral distances 52-391 km was collected and carefully evaluated. Nine broad-band stations were selected to invert full waveforms for the centroid position (horizontal and vertical) and for the focal mechanism solution. The first-arrival travel times, polarities and low-frequency full waveforms (0.03-0.08 Hz) are consistently explained in this paper as caused by a shallow source of the strike-slip mechanism. This finding indicates causal relation of this earthquake to the W-E trending South El-Alamein fault, which developed in Late Cretaceous as dextral strike slip fault. Recent activity of this fault, proven by the studied rare earthquake, is of fundamental importance for future seismic hazard evaluations, underlined by proximity (∼65 km) of the source zone to the first nuclear power plant planned site in Egypt. Safe exploration and possible future exploitation of hydrocarbon reserves, reported around El-Alamein fault in the last decade, cannot be made without considering the seismic potential of this fault.

  5. A Study of Interactions Between Thrust and Strike-slip Faults

    Directory of Open Access Journals (Sweden)

    Jeng-Cheng Wang

    2013-01-01

    Full Text Available A 3-D finite difference method is applied in this study to investigate a spontaneous rupture within a fault system which includes a primary thrust fault and two strike-slip sub-faults. With the occurrence of a rupture on a fault, the rupture condition follows Coulomb¡¦s friction law wherein the stress-slip obeys the slip-weakening fracture criteria. To overcome the geometrical complexity of such a system, a finite difference method is encoded in two different coordinate systems; then, the calculated displacements are connected between the two systems using a 2-D interpolation technique. The rupture is initiated at the center of the main fault under the compression of regional tectonic stresses and then propagates to the boundaries whereby the main fault rupture triggers two strike-slip sub-faults. Simulation results suggest that the triggering of two sub-faults is attributed to two primary factors, regional tectonic stresses and the relative distances between the two sub-faults and the main fault.

  6. Strike-slip pull-apart process and emplacement of Xiangshan uranium-producing volcanic basin

    International Nuclear Information System (INIS)

    Qiu Aijin; Guo Lingzhi; Shu Liangshu

    2001-01-01

    Xiangshan volcanic basin is one of the famous uranium-producing volcanic basins in China. Emplacement mechanism of Xiangshan uranium-producing volcanic basin is discussed on the basis of the latest research achievements of deep geology in Xiangshan area and the theory of continental dynamics. The study shows that volcanic activity in Xiangshan volcanic basin may be divided into two cycles, and its emplacement is controlled by strike-ship pull-apart process originated from the deep regional faults. Volcanic apparatus in the first cycle was emplaced in EW-trending structure activated by clockwise strike-slipping of NE-trending deep fault, forming the EW-trending fissure-type volcanic effusion belt. Volcanic apparatus in the second cycle was emplaced at junction points of SN-trending pull-apart structure activated by sinistral strike-slipping of NE-trending deep faults and EW-trending basement faults causing the center-type volcanic magma effusion and extrusion. Moreover, the formation mechanism of large-rich uranium deposits is discussed as well

  7. Geometry and kinematics of adhesive wear in brittle strike-slip fault zones

    Science.gov (United States)

    Swanson, Mark T.

    2005-05-01

    Detailed outcrop surface mapping in Late Paleozoic cataclastic strike-slip faults of coastal Maine shows that asymmetric sidewall ripouts, 0.1-200 m in length, are a significant component of many mapped faults and an important wall rock deformation mechanism during faulting. The geometry of these structures ranges from simple lenses to elongate slabs cut out of the sidewalls of strike-slip faults by a lateral jump of the active zone of slip during adhesion along a section of the main fault. The new irregular trace of the active fault after this jump creates an indenting asperity that is forced to plow through the adjoining wall rock during continued adhesion or be cut off by renewed motion along the main section of the fault. Ripout translation during adhesion sets up the structural asymmetry with trailing extensional and leading contractional ends to the ripout block. The inactive section of the main fault trace at the trailing end can develop a 'sag' or 'half-graben' type geometry due to block movement along the scallop-shaped connecting ramp to the flanking ripout fault. Leading contractional ramps can develop 'thrust' type imbrication and forces the 'humpback' geometry to the ripout slab due to distortion of the inactive main fault surface by ripout translation. Similar asymmetric ripout geometries are recognized in many other major crustal scale strike-slip fault zones worldwide. Ripout structures in the 5-500 km length range can be found on the Atacama fault system of northern Chile, the Qujiang and Xiaojiang fault zones in western China, the Yalakom-Hozameen fault zone in British Columbia and the San Andreas fault system in southern California. For active crustal-scale faults the surface expression of ripout translation includes a coupled system of extensional trailing ramps as normal oblique-slip faults with pull-apart basin sedimentation and contractional leading ramps as oblique thrust or high angle reverse faults with associated uplift and erosion. The

  8. A Possible Differentially Shortened Strike-slip Plate Boundary: the Okhotsk Plate Example.

    Science.gov (United States)

    Hindle, D.; Egorov, V.; Mackey, K. G.; Fujita, K.

    2004-12-01

    The Okhotsk plate has been postulated based on a combination of GPS geodetic inversions (REVEL1), seimsicity, geologic and lineament data. Lying between the North American and Eurasian plates, its northwestern corner would appear to be undergoing compression in a scissors motion between the two bounding plates. Extrusion tectonics along multiple, large strike-slip faults within the Okhotsk plate itself have been suggested to allow the escape of material away from the apex of Eurasia-North America. The plate boundary between Okhotsk and North America has been suggested to be diffuse, based on widely scattered minor seismicity. However, the large, left lateral, Ulakhan fault has also been suggested as a candidate plate boundary. We present field geological and geomorphological evidence of the partitioning of deformation between the Ulakhan fault, and several parallel and oblique, linked faults. The Ulakhan fault strand appears to have a maximum displacement of 24 km based on river valley offsets and closing large pull apart basins. Some of the displacement from the Ulakhan fault appears relayed into the plate margin along oblique trending, thrust/oblique slip faults. Estimated shortening over these faults is equivalent to the amount of shortening relayed into the plate margin from the plate boundary. There may be several thrust/oblique slip faults along the Ulakhan fault, which leads to the interesting situation of a segmented, strike-slip plate boundary being actively shortened in a margin parallel direction. This may be the result of postulated extrusion of the Okhotsk plate due to North America/Eurasia convergence. Such a situation would have important consequences for the interpretation of GPS data in a plate tectonic context.

  9. Evidence of extensional and strike-slip deformation in the offshore Gökova-Kos area affected by the July 2017 Mw6.6 Bodrum-Kos earthquake, eastern Aegean Sea

    Science.gov (United States)

    Ocakoğlu, Neslihan; Nomikou, Paraskevi; İşcan, Yeliz; Loreto, Maria Filomena; Lampridou, Danai

    2018-01-01

    The interpretation of new multichannel seismic profiles and previously published high-resolution swath and seismic reflection data from the Gökova Gulf and southeast of Kos Island in the eastern Aegean Sea revealed new morphotectonic features related to the July 20, 2017 Mw6.6 Bodrum-Kos earthquake offshore between Kos Island and the Bodrum Peninsula. The seafloor morphology in the northern part of the gulf is characterized by south-dipping E-W-oriented listric normal faults. These faults bend to a ENE-WSW direction towards Kos Island, and then extend parallel to the southern coastline. A left-lateral SW-NE strike-slip fault zone is mapped with segments crossing the Gökova Gulf from its northern part to south of Kos Island. This fault zone intersects and displaces the deep basins in the gulf. The basins are thus interpreted as the youngest deformed features in the study area. The strike-slip faults also produce E-W-oriented ridges between the basin segments, and the ridge-related vertical faults are interpreted as reverse faults. This offshore study reveals that the normal and strike-slip faults are well correlated with the focal mechanism solutions of the recent earthquake and general seismicity of the Gökova Gulf. Although the complex morphotectonic features could suggest that the area is under a transtensional regime, kinematic elements normally associated with a transtensional system are missing. At present, the Gökova Gulf is experiencing strike-slip motion with dominant extensional deformation, rather than transtensional deformation.

  10. Evidence of extensional and strike-slip deformation in the offshore Gökova-Kos area affected by the July 2017 Mw6.6 Bodrum-Kos earthquake, eastern Aegean Sea

    Science.gov (United States)

    Ocakoğlu, Neslihan; Nomikou, Paraskevi; İşcan, Yeliz; Loreto, Maria Filomena; Lampridou, Danai

    2018-06-01

    The interpretation of new multichannel seismic profiles and previously published high-resolution swath and seismic reflection data from the Gökova Gulf and southeast of Kos Island in the eastern Aegean Sea revealed new morphotectonic features related to the July 20, 2017 Mw6.6 Bodrum-Kos earthquake offshore between Kos Island and the Bodrum Peninsula. The seafloor morphology in the northern part of the gulf is characterized by south-dipping E-W-oriented listric normal faults. These faults bend to a ENE-WSW direction towards Kos Island, and then extend parallel to the southern coastline. A left-lateral SW-NE strike-slip fault zone is mapped with segments crossing the Gökova Gulf from its northern part to south of Kos Island. This fault zone intersects and displaces the deep basins in the gulf. The basins are thus interpreted as the youngest deformed features in the study area. The strike-slip faults also produce E-W-oriented ridges between the basin segments, and the ridge-related vertical faults are interpreted as reverse faults. This offshore study reveals that the normal and strike-slip faults are well correlated with the focal mechanism solutions of the recent earthquake and general seismicity of the Gökova Gulf. Although the complex morphotectonic features could suggest that the area is under a transtensional regime, kinematic elements normally associated with a transtensional system are missing. At present, the Gökova Gulf is experiencing strike-slip motion with dominant extensional deformation, rather than transtensional deformation.

  11. The role of the East Asian active margin in widespread extensional and strike-slip deformation in East Asia

    NARCIS (Netherlands)

    Schellart, Wouter P.; Lister, G. S.

    2005-01-01

    East Asia is a region of widespread deformation, dominated by normal and strike-slip faults. Deformation has been interpreted to result from extrusion tectonics related to the India-Eurasia collision, which started in the Early Eocene. In East and SE China, however, deformation started earlier than

  12. Strike-Slip Fault Deformation and Its Control in Hydrocarbon Trapping in Ketaling Area, Jambi Subbasin, Indonesia

    Science.gov (United States)

    Ramadhan, Aldis; Badai Samudra, Alexis; Jaenudin; Puji Lestari, Enik; Saputro, Julian; Sugiono; Hirosiadi, Yosi; Amrullah, Indi

    2018-03-01

    Geologically, Ketaling area consists of a local high considered as flexure margin of Tempino-Kenali Asam Deep in west part and graben in east part also known as East Ketaling Deep. Numerous proven plays were established in Ketaling area with reservoir in early Miocene carbonate and middle Miocene sand. This area underwent several major deformations. Faults are developed widely, yet their geometrical features and mechanisms of formation remained so far indistinct, which limited exploration activities. With new three-dimensional seismic data acquired in 2014, this area evidently interpreted as having strike-slip mechanism. The objective of this study is to examine characteristic of strike slip fault and its affect to hydrocarbon trapping in Ketaling Area. Structural pattern and characteristic of strike slip fault deformation was examined with integration of normal seismic with variance seismic attribute analysis and the mapping of Syn-rift to Post-rift horizon. Seismic flattening on 2D seismic cross section with NW-SE direction is done to see the structural pattern related to horst (paleohigh) and graben. Typical flower structure, branching strike-slip fault system and normal fault in synrift sediment clearly showed in section. An echelon pattern identified from map view as the result of strike slip mechanism. Detail structural geology analysis show the normal fault development which has main border fault in the southern of Ketaling area dipping to the Southeast-East with NE-SW lineament. These faults related to rift system in Ketaling area. NW-SE folds with reactive NE-SW fault which act as hydrocarbon trapping in the shallow zone. This polyphase tectonic formed local graben, horst and inverted structure developed a good kitchen area (graben) and traps (horst, inverted structure). Subsequently, hydrocarbon accumulation potentials such as basement fractures, inverted syn-rift deposit and shallow zone are very interesting to explore in this area.

  13. Analysis of the growth of strike-slip faults using effective medium theory

    Energy Technology Data Exchange (ETDEWEB)

    Aydin, A.; Berryman, J.G.

    2009-10-15

    Increases in the dimensions of strike-slip faults including fault length, thickness of fault rock and the surrounding damage zone collectively provide quantitative definition of fault growth and are commonly measured in terms of the maximum fault slip. The field observations indicate that a common mechanism for fault growth in the brittle upper crust is fault lengthening by linkage and coalescence of neighboring fault segments or strands, and fault rock-zone widening into highly fractured inner damage zone via cataclastic deformation. The most important underlying mechanical reason in both cases is prior weakening of the rocks surrounding a fault's core and between neighboring fault segments by faulting-related fractures. In this paper, using field observations together with effective medium models, we analyze the reduction in the effective elastic properties of rock in terms of density of the fault-related brittle fractures and fracture intersection angles controlled primarily by the splay angles. Fracture densities or equivalent fracture spacing values corresponding to the vanishing Young's, shear, and quasi-pure shear moduli were obtained by extrapolation from the calculated range of these parameters. The fracture densities or the equivalent spacing values obtained using this method compare well with the field data measured along scan lines across the faults in the study area. These findings should be helpful for a better understanding of the fracture density/spacing distribution around faults and the transition from discrete fracturing to cataclastic deformation associated with fault growth and the related instabilities.

  14. The Trans-Rocky Mountain Fault System - A Fundamental Precambrian Strike-Slip System

    Science.gov (United States)

    Sims, P.K.

    2009-01-01

    Recognition of a major Precambrian continental-scale, two-stage conjugate strike-slip fault system - here designated as the Trans-Rocky Mountain fault system - provides new insights into the architecture of the North American continent. The fault system consists chiefly of steep linear to curvilinear, en echelon, braided and branching ductile-brittle shears and faults, and local coeval en echelon folds of northwest strike, that cut indiscriminately across both Proterozoic and Archean cratonic elements. The fault system formed during late stages of two distinct tectonic episodes: Neoarchean and Paleoproterozoic orogenies at about 2.70 and 1.70 billion years (Ga). In the Archean Superior province, the fault system formed (about 2.70-2.65 Ga) during a late stage of the main deformation that involved oblique shortening (dextral transpression) across the region and progressed from crystal-plastic to ductile-brittle deformation. In Paleoproterozoic terranes, the fault system formed about 1.70 Ga, shortly following amalgamation of Paleoproterozoic and Archean terranes and the main Paleoproterozoic plastic-fabric-producing events in the protocontinent, chiefly during sinistral transpression. The postulated driving force for the fault system is subcontinental mantle deformation, the bottom-driven deformation of previous investigators. This model, based on seismic anisotropy, invokes mechanical coupling and subsequent shear between the lithosphere and the asthenosphere such that a major driving force for plate motion is deep-mantle flow.

  15. Fault Branching and Long-Term Earthquake Rupture Scenario for Strike-Slip Earthquake

    Science.gov (United States)

    Klinger, Y.; CHOI, J. H.; Vallage, A.

    2017-12-01

    Careful examination of surface rupture for large continental strike-slip earthquakes reveals that for the majority of earthquakes, at least one major branch is involved in the rupture pattern. Often, branching might be either related to the location of the epicenter or located toward the end of the rupture, and possibly related to the stopping of the rupture. In this work, we examine large continental earthquakes that show significant branches at different scales and for which ground surface rupture has been mapped in great details. In each case, rupture conditions are described, including dynamic parameters, past earthquakes history, and regional stress orientation, to see if the dynamic stress field would a priori favor branching. In one case we show that rupture propagation and branching are directly impacted by preexisting geological structures. These structures serve as pathways for the rupture attempting to propagate out of its shear plane. At larger scale, we show that in some cases, rupturing a branch might be systematic, hampering possibilities for the development of a larger seismic rupture. Long-term geomorphology hints at the existence of a strong asperity in the zone where the rupture branched off the main fault. There, no evidence of throughgoing rupture could be seen along the main fault, while the branch is well connected to the main fault. This set of observations suggests that for specific configurations, some rupture scenarios involving systematic branching are more likely than others.

  16. Influence of fault steps on rupture termination of strike-slip earthquake faults

    Science.gov (United States)

    Li, Zhengfang; Zhou, Bengang

    2018-03-01

    A statistical analysis was completed on the rupture data of 29 historical strike-slip earthquakes across the world. The purpose of this study is to examine the effects of fault steps on the rupture termination of these events. The results show good correlations between the type and length of steps with the seismic rupture and a poor correlation between the step number and seismic rupture. For different magnitude intervals, the smallest widths of the fault steps (Lt) that can terminate the rupture propagation are variable: Lt = 3 km for Ms 6.5 6.9, Lt = 4 km for Ms 7.0 7.5, Lt = 6 km for Ms 7.5 8.0, and Lt = 8 km for Ms 8.0 8.5. The dilational fault step is easier to rupture through than the compression fault step. The smallest widths of the fault step for the rupture arrest can be used as an indicator to judge the scale of the rupture termination of seismic faults. This is helpful for research on fault segmentation, as well as estimating the magnitude of potential earthquakes, and is thus of significance for the assessment of seismic risks.

  17. The geometry of the active strike-slip El Tigre Fault, Precordillera of San Juan, Central-Western Argentina: integrating resistivity surveys with structural and geomorphological data

    Science.gov (United States)

    Fazzito, Sabrina Y.; Cortés, José M.; Rapalini, Augusto E.; Terrizzano, Carla M.

    2013-07-01

    The geometry and related geomorphological features of the right-lateral strike-slip El Tigre Fault, one of the main morphostructural discontinuities in the Central-Western Precordillera of Argentina, were investigated. Achievements of this survey include: recognition of structural and geometrical discontinuities along the fault trace, identification and classification of landforms associated with local transpressional and transtensional sectors, observation of significant changes in the fault strike and detection of right and left bends of different wavelength. In the Central Segment of the El Tigre Fault, 2D electrical resistivity tomography surveys were carried out across the fault zone. The resistivity imaging permitted to infer the orientation of the main fault surface, the presence of blind fault branches along the fault zone, tectonic tilting of the Quaternary sedimentary cover, subsurface structure of pressure ridges and depth to the water table. Based on this information, it is possible to characterize the El Tigre Fault also as an important hydro-geological barrier. Our survey shows that the main fault surface changes along different segments from a high-angle to a subvertical setting whilst the vertical-slip component is either reverse or normal, depending on the local transpressive or transtensive regime induced by major bends along the trace. These local variations are expressed as sections of a few kilometres in length with relatively homogeneous behaviour and frequently separated by oblique or transversal structures.

  18. Structural characteristics and implication on tectonic evolution of the Daerbute strike-slip fault in West Junggar area, NW China

    Science.gov (United States)

    Wu, Kongyou; Pei, Yangwen; Li, Tianran; Wang, Xulong; Liu, Yin; Liu, Bo; Ma, Chao; Hong, Mei

    2018-03-01

    The Daerbute fault zone, located in the northwestern margin of the Junggar basin, in the Central Asian Orogenic Belt, is a regional strike-slip fault with a length of 400 km. The NE-SW trending Daerbute fault zone presents a distinct linear trend in plain view, cutting through both the Zair Mountain and the Hala'alate Mountain. Because of the intense contraction and shearing, the rocks within the fault zone experienced high degree of cataclasis, schistosity, and mylonization, resulting in rocks that are easily eroded to form a valley with a width of 300-500 m and a depth of 50-100 m after weathering and erosion. The well-exposed outcrops along the Daerbute fault zone present sub-horizontal striations and sub-vertical fault steps, indicating sub-horizontal shearing along the observed fault planes. Flower structures and horizontal drag folds are also observed in both the well-exposed outcrops and high-resolution satellite images. The distribution of accommodating strike-slip splay faults, e.g., the 973-pluton fault and the Great Jurassic Trough fault, are in accordance with the Riedel model of simple shear. The seismic and time-frequency electromagnetic (TFEM) sections also demonstrate the typical strike-slip characteristics of the Daerbute fault zone. Based on detailed field observations of well-exposed outcrops and seismic sections, the Daerbute fault can be subdivided into two segments: the western segment presents multiple fault cores and damage zones, whereas the eastern segment only presents a single fault core, in which the rocks experienced a higher degree of rock cataclasis, schistosity, and mylonization. In the central overlapping portion between the two segments, the sediments within the fault zone are primarily reddish sandstones, conglomerates, and some mudstones, of which the palynological tests suggest middle Permian as the timing of deposition. The deformation timing of the Daerbute fault was estimated by integrating the depocenters' basinward

  19. The Damage and Geochemical Signature of a Crustal Scale Strike-Slip Fault Zone

    Science.gov (United States)

    Gomila, R.; Mitchell, T. M.; Arancibia, G.; Jensen Siles, E.; Rempe, M.; Cembrano, J. M.; Faulkner, D. R.

    2013-12-01

    Fluid-flow migration in the upper crust is strongly controlled by fracture network permeability and connectivity within fault zones, which can lead to fluid-rock chemical interaction represented as mineral precipitation in mesh veins and/or mineralogical changes (alteration) of the host rock. While the dimensions of fault damage zones defined by fracture intensity is beginning to be better understood, how such dimensions compare to the size of alteration zones is less well known. Here, we show quantitative structural and chemical analyses as a function of distance from a crustal-scale strike-slip fault in the Atacama Fault System, Northern Chile, to compare fault damage zone characteristics with its geochemical signature. The Jorgillo Fault (JF) is a ca. 18 km long NNW striking strike-slip fault cutting Mesozoic rocks with sinistral displacement of ca. 4 km. In the study area, the JF cuts through orthogranulitic and gabbroic rocks at the west (JFW) and the east side (JFE), respectively. A 200 m fault perpendicular transect was mapped and sampled for structural and XRF analyses of the core, damage zone and protolith. The core zone consists of a ca. 1 m wide cataclasite zone bounded by two fault gouge zones ca. 40 cm. The damage zone width defined by fracture density is ca. 50 m wide each side of the core. The damage zone in JFW is characterized by NW-striking subvertical 2 cm wide cataclastic rocks and NE-striking milimetric open fractures. In JFE, 1-20 mm wide chlorite, quartz-epidote and quartz-calcite veins, cut the gabbro. Microfracture analysis in JFW reveal mm-wide cataclasitic/ultracataclasitic bands with clasts of protolith and chlorite orientated subparallel to the JF in the matrix, calcite veins in a T-fractures orientation, and minor polidirectional chlorite veins. In JFE, chlorite filled conjugate fractures with syntaxial growth textures and evidence for dilational fracturing processes are seen. Closest to the core, calcite veins crosscut chlorite veins

  20. The Implications of Strike-Slip Earthquake Source Properties on the Transform Boundary Development Process

    Science.gov (United States)

    Neely, J. S.; Huang, Y.; Furlong, K.

    2017-12-01

    Subduction-Transform Edge Propagator (STEP) faults, produced by the tearing of a subducting plate, allow us to study the development of a transform plate boundary and improve our understanding of both long-term geologic processes and short-term seismic hazards. The 280 km long San Cristobal Trough (SCT), formed by the tearing of the Australia plate as it subducts under the Pacific plate near the Solomon and Vanuatu subduction zones, shows along-strike variations in earthquake behaviors. The segment of the SCT closest to the tear rarely hosts earthquakes > Mw 6, whereas the SCT sections more than 80 - 100 km from the tear experience Mw7 earthquakes with repeated rupture along the same segments. To understand the effect of cumulative displacement on SCT seismicity, we analyze b-values, centroid-time delays and corner frequencies of the SCT earthquakes. We use the spectral ratio method based on Empirical Green's Functions (eGfs) to isolate source effects from propagation and site effects. We find high b-values along the SCT closest to the tear with values decreasing with distance before finally increasing again towards the far end of the SCT. Centroid time-delays for the Mw 7 strike-slip earthquakes increase with distance from the tear, but corner frequency estimates for a recent sequence of Mw 7 earthquakes are approximately equal, indicating a growing complexity in earthquake behavior with distance from the tear due to a displacement-driven transform boundary development process (see figure). The increasing complexity possibly stems from the earthquakes along the eastern SCT rupturing through multiple asperities resulting in multiple moment pulses. If not for the bounding Vanuatu subduction zone at the far end of the SCT, the eastern SCT section, which has experienced the most displacement, might be capable of hosting larger earthquakes. When assessing the seismic hazard of other STEP faults, cumulative fault displacement should be considered a key input in

  1. Long term fault system reorganization of convergent and strike-slip systems

    Science.gov (United States)

    Cooke, M. L.; McBeck, J.; Hatem, A. E.; Toeneboehn, K.; Beyer, J. L.

    2017-12-01

    Laboratory and numerical experiments representing deformation over many earthquake cycles demonstrate that fault evolution includes episodes of fault reorganization that optimize work on the fault system. Consequently, the mechanical and kinematic efficiencies of fault systems do not increase monotonically through their evolution. New fault configurations can optimize the external work required to accommodate deformation, suggesting that changes in system efficiency can drive fault reorganization. Laboratory evidence and numerical results show that fault reorganization within accretion, strike-slip and oblique convergent systems is associated with increasing efficiency due to increased fault slip (frictional work and seismic energy) and commensurate decreased off-fault deformation (internal work and work against gravity). Between episodes of fault reorganization, fault systems may become less efficient as they produce increasing off fault deformation. For example, laboratory and numerical experiments show that the interference and interaction between different fault segments may increase local internal work or that increasing convergence can increase work against gravity produced by a fault system. This accumulation of work triggers fault reorganization as stored work provides the energy required to grow new faults that reorganize the system to a more efficient configuration. The results of laboratory and numerical experiments reveal that we should expect crustal fault systems to reorganize following periods of increasing inefficiency, even in the absence of changes to the tectonic regime. In other words, fault reorganization doesn't require a change in tectonic loading. The time frame of fault reorganization depends on fault system configuration, strain rate and processes that relax stresses within the crust. For example, stress relaxation may keep pace with stress accumulation, which would limit the increase in the internal work and gravitational work so that

  2. Earthquake Activities Along the Strike-Slip Fault System on the Thailand-Myanmar Border

    Directory of Open Access Journals (Sweden)

    Santi Pailoplee

    2014-01-01

    Full Text Available This study investigates the present-day seismicity along the strike-slip fault system on the Thailand-Myanmar border. Using the earthquake catalogue the earthquake parameters representing seismic activities were evaluated in terms of the possible maximum magnitude, return period and earthquake occurrence probabilities. Three different hazardous areas could be distinguished from the obtained results. The most seismic-prone area was located along the northern segment of the fault system and can generate earthquakes of magnitude 5.0, 5.8, and 6.8 mb in the next 5, 10, and 50 years, respectively. The second most-prone area was the southern segment where earthquakes of magnitude 5.0, 6.0, and 7.0 mb might be generated every 18, 60, and 300 years, respectively. For the central segment, there was less than 30 and 10% probability that 6.0- and 7.0-mb earthquakes will be generated in the next 50 years. With regards to the significant infrastructures (dams in the vicinity, the operational Wachiralongkorn dam is situated in a low seismic hazard area with a return period of around 30 - 3000 years for a 5.0 - 7.0 mb earthquake. In contrast, the Hut Gyi, Srinakarin and Tha Thung Na dams are seismically at risk for earthquakes of mb 6.4 - 6.5 being generated in the next 50 years. Plans for a seismic-retrofit should therefore be completed and implemented while seismic monitoring in this region is indispensable.

  3. The San Andreas Fault and a Strike-slip Fault on Europa

    Science.gov (United States)

    1998-01-01

    The mosaic on the right of the south polar region of Jupiter's moon Europa shows the northern 290 kilometers (180 miles) of a strike-slip fault named Astypalaea Linea. The entire fault is about 810 kilometers (500 miles) long, the size of the California portion of the San Andreas fault on Earth which runs from the California-Mexico border north to the San Francisco Bay. The left mosaic shows the portion of the San Andreas fault near California's san Francisco Bay that has been scaled to the same size and resolution as the Europa image. Each covers an area approximately 170 by 193 kilometers(105 by 120 miles). The red line marks the once active central crack of the Europan fault (right) and the line of the San Andreas fault (left). A strike-slip fault is one in which two crustal blocks move horizontally past one another, similar to two opposing lanes of traffic. The overall motion along the Europan fault seems to have followed a continuous narrow crack along the entire length of the feature, with a path resembling stepson a staircase crossing zones which have been pulled apart. The images show that about 50 kilometers (30 miles) of displacement have taken place along the fault. Opposite sides of the fault can be reconstructed like a puzzle, matching the shape of the sides as well as older individual cracks and ridges that had been broken by its movements. Bends in the Europan fault have allowed the surface to be pulled apart. This pulling-apart along the fault's bends created openings through which warmer, softer ice from below Europa's brittle ice shell surface, or frozen water from a possible subsurface ocean, could reach the surface. This upwelling of material formed large areas of new ice within the boundaries of the original fault. A similar pulling apart phenomenon can be observed in the geological trough surrounding California's Salton Sea, and in Death Valley and the Dead Sea. In those cases, the pulled apart regions can include upwelled materials, but may

  4. Role of N-S strike-slip faulting in structuring of north-eastern Tunisia; geodynamic implications

    Science.gov (United States)

    Arfaoui, Aymen; Soumaya, Abdelkader; Ben Ayed, Noureddine; Delvaux, Damien; Ghanmi, Mohamed; Kadri, Ali; Zargouni, Fouad

    2017-05-01

    Three major compressional events characterized by folding, thrusting and strike-slip faulting occurred in the Eocene, Late Miocene and Quaternary along the NE Tunisian domain between Bou Kornine-Ressas-Msella and Cap Bon Peninsula. During the Plio-Quaternary, the Grombalia and Mornag grabens show a maximum of collapse in parallelism with the NNW-SSE SHmax direction and developed as 3rd order distensives zones within a global compressional regime. Using existing tectonic and geophysical data supplemented by new fault-kinematic observations, we show that Cenozoic deformation of the Mesozoic sedimentary sequences is dominated by first order N-S faults reactivation, this sinistral wrench system is responsible for the formation of strike-slip duplexes, thrusts, folds and grabens. Following our new structural interpretation, the major faults of N-S Axis, Bou Kornine-Ressas-Messella (MRB) and Hammamet-Korbous (HK) form an N-S first order compressive relay within a left lateral strike-slip duplex. The N-S master MRB fault is dominated by contractional imbricate fans, while the parallel HK fault is characterized by a trailing of extensional imbricate fans. The Eocene and Miocene compression phases in the study area caused sinistral strike-slip reactivation of pre-existing N-S faults, reverse reactivation of NE-SW trending faults and normal-oblique reactivation of NW-SE faults, creating a NE-SW to N-S trending system of east-verging folds and overlaps. Existing seismic tomography images suggest a key role for the lithospheric subvertical tear or STEP fault (Slab Transfer Edge Propagator) evidenced below this region on the development of the MRB and the HK relay zone. The presence of extensive syntectonic Pliocene on top of this crustal scale fault may be the result of a recent lithospheric vertical kinematic of this STEP fault, due to the rollback and lateral migration of the Calabrian slab eastward.

  5. Using an Earthquake Simulator to Model Tremor Along a Strike Slip Fault

    Science.gov (United States)

    Cochran, E. S.; Richards-Dinger, K. B.; Kroll, K.; Harrington, R. M.; Dieterich, J. H.

    2013-12-01

    We employ the earthquake simulator, RSQSim, to investigate the conditions under which tremor occurs in the transition zone of the San Andreas fault. RSQSim is a computationally efficient method that uses rate- and state- dependent friction to simulate a wide range of event sizes for long time histories of slip [Dieterich and Richards-Dinger, 2010; Richards-Dinger and Dieterich, 2012]. RSQSim has been previously used to investigate slow slip events in Cascadia [Colella et al., 2011; 2012]. Earthquakes, tremor, slow slip, and creep occurrence are primarily controlled by the rate and state constants a and b and slip speed. We will report the preliminary results of using RSQSim to vary fault frictional properties in order to better understand rupture dynamics in the transition zone using observed characteristics of tremor along the San Andreas fault. Recent studies of tremor along the San Andreas fault provide information on tremor characteristics including precise locations, peak amplitudes, duration of tremor episodes, and tremor migration. We use these observations to constrain numerical simulations that examine the slip conditions in the transition zone of the San Andreas Fault. Here, we use the earthquake simulator, RSQSim, to conduct multi-event simulations of tremor for a strike slip fault modeled on Cholame section of the San Andreas fault. Tremor was first observed on the San Andreas fault near Cholame, California near the southern edge of the 2004 Parkfield rupture [Nadeau and Dolenc, 2005]. Since then, tremor has been observed across a 150 km section of the San Andreas with depths between 16-28 km and peak amplitudes that vary by a factor of 7 [Shelly and Hardebeck, 2010]. Tremor episodes, comprised of multiple low frequency earthquakes (LFEs), tend to be relatively short, lasting tens of seconds to as long as 1-2 hours [Horstmann et al., in review, 2013]; tremor occurs regularly with some tremor observed almost daily [Shelly and Hardebeck, 2010; Horstmann

  6. Effects of Strike-Slip Fault Segmentation on Earthquake Energy and Seismic Hazard

    Science.gov (United States)

    Madden, E. H.; Cooke, M. L.; Savage, H. M.; McBeck, J.

    2014-12-01

    Many major strike-slip faults are segmented along strike, including those along plate boundaries in California and Turkey. Failure of distinct fault segments at depth may be the source of multiple pulses of seismic radiation observed for single earthquakes. However, how and when segmentation affects fault behavior and energy release is the basis of many outstanding questions related to the physics of faulting and seismic hazard. These include the probability for a single earthquake to rupture multiple fault segments and the effects of segmentation on earthquake magnitude, radiated seismic energy, and ground motions. Using numerical models, we quantify components of the earthquake energy budget, including the tectonic work acting externally on the system, the energy of internal rock strain, the energy required to overcome fault strength and initiate slip, the energy required to overcome frictional resistance during slip, and the radiated seismic energy. We compare the energy budgets of systems of two en echelon fault segments with various spacing that include both releasing and restraining steps. First, we allow the fault segments to fail simultaneously and capture the effects of segmentation geometry on the earthquake energy budget and on the efficiency with which applied displacement is accommodated. Assuming that higher efficiency correlates with higher probability for a single, larger earthquake, this approach has utility for assessing the seismic hazard of segmented faults. Second, we nucleate slip along a weak portion of one fault segment and let the quasi-static rupture propagate across the system. Allowing fractures to form near faults in these models shows that damage develops within releasing steps and promotes slip along the second fault, while damage develops outside of restraining steps and can prohibit slip along the second fault. Work is consumed in both the propagation of and frictional slip along these new fractures, impacting the energy available

  7. Transition from strike-slip faulting to oblique subduction: active tectonics at the Puysegur Margin, South New Zealand

    Science.gov (United States)

    Lamarche, Geoffroy; Lebrun, Jean-Frédéric

    2000-01-01

    South of New Zealand the Pacific-Australia (PAC-AUS) plate boundary runs along the intracontinental Alpine Fault, the Puysegur subduction front and the intraoceanic Puysegur Fault. The Puysegur Fault is located along Puysegur Ridge, which terminates at ca. 47°S against the continental Puysegur Bank in a complex zone of deformation called the Snares Zone. At Puysegur Trench, the Australian Plate subducts beneath Puysegur Bank and the Fiordland Massif. East of Fiordland and Puysegur Bank, the Moonlight Fault System (MFS) represents the Eocene strike-slip plate boundary. Interpretation of seafloor morphology and seismic reflection profiles acquired over Puysegur Bank and the Snares Zone allows study of the transition from intraoceanic strike-slip faulting along the Puysegur Ridge to oblique subduction at the Puysegur Trench and to better understand the genetic link between the Puysegur Fault and the MFS. Seafloor morphology is interpreted from a bathymetric dataset compiled from swath bathymetry data acquired during the 1993 Geodynz survey, and single beam echo soundings acquired by the NZ Royal Navy. The Snares Zone is the key transition zone from strike-slip faulting to subduction. It divides into three sectors, namely East, NW and SW sectors. A conspicuous 3600 m-deep trough (the Snares Trough) separates the NW and East sectors. The East sector is characterised by the NE termination of Puysegur Ridge into right-stepping en echelon ridges that accommodate a change of strike from the Puysegur Fault to the MFS. Between 48°S and 47°S, in the NW sector and the Snares Trough, a series of transpressional faults splay northwards from the Puysegur Fault. Between 49°50'S and 48°S, thrusts develop progressively at Puysegur Trench into a decollement. North of 48°S the Snares Trough develops between two splays of the Puysegur Fault, indicating superficial extension associated with the subsidence of Puysegur Ridge. Seismic reflection profiles and bathymetric maps show a

  8. Strike-slip linked core complexes: A new kinematic model of basement rock exhumation in a crustal-scale fault system

    Science.gov (United States)

    Meyer, Sven Erik; Passchier, Cees; Abu-Alam, Tamer; Stüwe, Kurt

    2014-05-01

    Metamorphic core complexes usually develop as extensional features during continental crustal thinning, such as the Basin and Range and the Aegean Terrane. The Najd fault system in Saudi Arabia is a 2000 km-long and 400 km-wide complex network of crustal-scale strike-slip shear zones in a Neoproterozoic collision zone. Locally, the anastomosing shear zones lead to exhumation of lower crustal segments and represent a new kinematic model for the development of core complexes. We report on two such structures: the Qazaz complex in Saudi Arabia and the Hafafit complex in Egypt. The 15 km-wide Qazaz complex is a triangular dome of gently dipping mylonitic foliations within the 140 km-long sinistral strike-slip Qazaz mylonite zone. The gneissic dome consists of high-grade rocks, surrounded by low-grade metasediments and metavolcanics. The main SE-trending strike-slip Qazaz shear zone splits southwards into two branches around the gneiss dome: the western branch is continuous with the shallow dipping mylonites of the dome core, without overprinting, and changes by more than 90 degrees from a NS-trending strike-slip zone to an EW-trending 40 degree south-dipping detachment that bounds the gneiss dome to the south. The eastern SE-trending sinistral strike-slip shear zone branch is slightly younger and transects the central dome fabrics. The gneiss dome appears to have formed along a jog in the strike-slip shear zone during 40 km of horizontal strike-slip motion, which caused local exhumation of lower crustal rocks by 25 km along the detachment. The eastern shear zone branch formed later during exhumation, transacted the gneiss dome and offset the two parts by another 70 km. The Hafafit core complex in Egypt is of similar shape and size to the Qazaz structure, but forms the northern termination of a sinistral strike-slip zone that is at least 100 km in length. This zone may continue into Saudi Arabia as the Ajjaj shear zone for another 100 km. The NW trending strike slip

  9. Structural setting and kinematics of Nubian fault system, SE Western Desert, Egypt: An example of multi-reactivated intraplate strike-slip faults

    Science.gov (United States)

    Sakran, Shawky; Said, Said Mohamed

    2018-02-01

    Detailed surface geological mapping and subsurface seismic interpretation have been integrated to unravel the structural style and kinematic history of the Nubian Fault System (NFS). The NFS consists of several E-W Principal Deformation Zones (PDZs) (e.g. Kalabsha fault). Each PDZ is defined by spectacular E-W, WNW and ENE dextral strike-slip faults, NNE sinistral strike-slip faults, NE to ENE folds, and NNW normal faults. Each fault zone has typical self-similar strike-slip architecture comprising multi-scale fault segments. Several multi-scale uplifts and basins were developed at the step-over zones between parallel strike-slip fault segments as a result of local extension or contraction. The NNE faults consist of right-stepping sinistral strike-slip fault segments (e.g. Sin El Kiddab fault). The NNE sinistral faults extend for long distances ranging from 30 to 100 kms and cut one or two E-W PDZs. Two nearly perpendicular strike-slip tectonic regimes are recognized in the NFS; an inactive E-W Late Cretaceous - Early Cenozoic dextral transpression and an active NNE sinistral shear.

  10. Late Pleistocene-Holocene Activity of the Strike-slip Xianshuihe Fault Zone, Tibetan Plateau, Inferred from Tectonic Landforms

    Science.gov (United States)

    Lin, A.; Yan, B.

    2017-12-01

    Knowledges on the activity of the strike-slip fault zones on the Tibetan Plateau have been promoted greatly by the interpretation of remote sensing images (Molnar and Tapponnier, 1975; Tapponnier and Molnar, 1977). The active strike-slip Xianshuihe-Xiaojiang Fault System (XXFS), with the geometry of an arc projecting northeastwards, plays an important role in the crustal deformation of the Tibetan Plateau caused by the continental collision between the Indian and Eurasian plates. The Xianshuihe Fault Zone (XFZ) is located in the central segment of the XXFS and extends for 370 km, with a maximum sinistral offset of 60 km since 13‒5 Ma. In this study, we investigated the tectonic landforms and slip rate along the central segment of the left-lateral strike-slip XFZ. Field investigations and analysis of ttectonic landforms show that horizontal offset has been accumulated on the topographical markers of different scales that developed since the Last Glacial Maximum (LGM). The central segment of the XFZ is composed of three major faults: Yalahe, Selaha, and Zheduotang faults showing a right-stepping echelon pattern, that is characterized by systematical offset of drainages, alluvial fans and terrace risers with typical scissoring structures, indicating a structural feature of left-lateral strike-slip fault. Based on the offset glacial morphology and radiocarbon dating ages, we estimate the Late Pleistocene-Holocene slip rate to be 10 mm/yr for the central segment of the XFZ, which is consistent with that estimated from the GPS observations and geological evidence as reported previously. Across the central segment of the XFZ, the major Selaha and Zheduotang faults participate a slip rate of 5.8 mm/yr and 3.4 mm/yr, respectively. Detailed investigations of tectonic landforms are essential for the understanding the activity of active faults. Our findings suggest that the left-lateral slipping of the XFZ partitions the deformation of eastward extrusion and northeastward

  11. Three-dimensional shuffling of horses in a strike-slip duplex: an example from the Lambertville sill, New Jersey

    Science.gov (United States)

    Laney, Stephen E.; Gates, Alexander E.

    1996-06-01

    Detailed analysis of a dextral strike-slip duplex within the relatively isotropic rocks of the Lambertville sill, New Jersey indicates that horses have experienced vertical, horizontal and oblique movements resulting from extrusional shuffling within a restraining bend. This is the first documentation of the three-dimensional movement of horses within a strike-slip duplex. Deformation within the duplex shows a complex system of early synthetic fractures and reverse faults followed by antithetic fractures which dissect previously continuous slab-shaped horses into diamond-shaped lenses. Most faults are oblique slip. Antithetic fault movements and clockwise rigid rotation of horses dominate the south half of the duplex and synthetic movements and counterclockwise rotations dominate the north half. Slickenline plunges on curved horse-bounding fault surfaces within the duplex range from nearly horizontal to 40° resulting in both lateral movements (middle) to normal movements (tails) on a single horse. Curved slickensides commonly have opposite senses of movement on either side of individual horses indicating relative emergence or submergence. Such a geometry could also result from a group of horses moving in the same oblique direction but at different rates. These complex extrusional-type movements were observed in both cross-sectional and plan views. The net result of the movements is a contraction or flattening of the duplex normal to the bounding faults. The horses shifted to accommodate this flattening as overall displacement was transferred between the bounding faults along curved internal faults.

  12. A nonlinear least-squares inverse analysis of strike-slip faulting with application to the San Andreas fault

    Science.gov (United States)

    Williams, Charles A.; Richardson, Randall M.

    1988-01-01

    A nonlinear weighted least-squares analysis was performed for a synthetic elastic layer over a viscoelastic half-space model of strike-slip faulting. Also, an inversion of strain rate data was attempted for the locked portions of the San Andreas fault in California. Based on an eigenvector analysis of synthetic data, it is found that the only parameter which can be resolved is the average shear modulus of the elastic layer and viscoelastic half-space. The other parameters were obtained by performing a suite of inversions for the fault. The inversions on data from the northern San Andreas resulted in predicted parameter ranges similar to those produced by inversions on data from the whole fault.

  13. Stress near geometrically complex strike-slip faults - Application to the San Andreas fault at Cajon Pass, southern California

    Science.gov (United States)

    Saucier, Francois; Humphreys, Eugene; Weldon, Ray, II

    1992-01-01

    A model is presented to rationalize the state of stress near a geometrically complex major strike-slip fault. Slip on such a fault creates residual stresses that, with the occurrence of several slip events, can dominate the stress field near the fault. The model is applied to the San Andreas fault near Cajon Pass. The results are consistent with the geological features, seismicity, the existence of left-lateral stress on the Cleghorn fault, and the in situ stress orientation in the scientific well, found to be sinistral when resolved on a plane parallel to the San Andreas fault. It is suggested that the creation of residual stresses caused by slip on a wiggle San Andreas fault is the dominating process there.

  14. Analogue Modeling of Oblique Convergent Strike-Slip Faulting and Application to The Seram Island, Eastern Indonesia

    Directory of Open Access Journals (Sweden)

    Benyamin Sapiie

    2014-12-01

    Full Text Available DOI:10.17014/ijog.v1i3.189Sandbox experiment is one of the types of analogue modeling in geological sciences in which the main purpose is simulating deformation style and structural evolution of the sedimentary basin.  Sandbox modeling is one of the effective ways in conducting physically modeling and evaluates complex deformation of sedimentary rocks. The main purpose of this paper is to evaluate structural geometry and deformation history of oblique convergent deformation using of integrated technique of analogue sandbox modeling applying to deformation of Seram Fold-Thrust-Belt (SFTB in the Seram Island, Eastern Indonesia. Oblique convergent strike-slip deformation has notoriously generated area with structural complex geometry and pattern resulted from role of various local parameters that control stress distributions. Therefore, a special technique is needed for understanding and solving such problem in particular to relate 3D fault geometry and its evolution. The result of four case (Case 1 to 4 modeling setting indicated that two of modeling variables clearly affected in our sandbox modeling results; these are lithological variation (mainly stratigraphy of Seram Island and pre-existing basement fault geometry (basement configuration. Lithological variation was mainly affected in the total number of faults development.  On the other hand, pre-existing basement fault geometry was highly influenced in the end results particularly fault style and pattern as demonstrated in Case 4 modeling.  In addition, this study concluded that deformation in the Seram Island is clearly best described using oblique convergent strike-slip (transpression stress system.

  15. Geologic Inheritance and Earthquake Rupture Processes: The 1905 M ≥ 8 Tsetserleg-Bulnay Strike-Slip Earthquake Sequence, Mongolia

    Science.gov (United States)

    Choi, Jin-Hyuck; Klinger, Yann; Ferry, Matthieu; Ritz, Jean-François; Kurtz, Robin; Rizza, Magali; Bollinger, Laurent; Davaasambuu, Battogtokh; Tsend-Ayush, Nyambayar; Demberel, Sodnomsambuu

    2018-02-01

    In 1905, 14 days apart, two M 8 continental strike-slip earthquakes, the Tsetserleg and Bulnay earthquakes, occurred on the Bulnay fault system, in Mongolia. Together, they ruptured four individual faults, with a total length of 676 km. Using submetric optical satellite images "Pleiades" with ground resolution of 0.5 m, complemented by field observation, we mapped in detail the entire surface rupture associated with this earthquake sequence. Surface rupture along the main Bulnay fault is 388 km in length, striking nearly E-W. The rupture is formed by a series of fault segments that are 29 km long on average, separated by geometric discontinuities. Although there is a difference of about 2 m in the average slip between the western and eastern parts of the Bulnay rupture, along-fault slip variations are overall limited, resulting in a smooth slip distribution, except for local slip deficit at segment boundaries. We show that damage, including short branches and secondary faulting, associated with the rupture propagation, occurred significantly more often along the western part of the Bulnay rupture, while the eastern part of the rupture appears more localized and thus possibly structurally simpler. Eventually, the difference of slip between the western and eastern parts of the rupture is attributed to this difference of rupture localization, associated at first order with a lateral change in the local geology. Damage associated to rupture branching appears to be located asymmetrically along the extensional side of the strike-slip rupture and shows a strong dependence on structural geologic inheritance.

  16. Effect of inherited structures on strike-slip plate boundaries: insight from analogue modelling of the central Levant Fracture System, Lebanon

    Science.gov (United States)

    Ghalayini, Ramadan; Daniel, Jean-Marc; Homberg, Catherine; Nader, Fadi

    2015-04-01

    Analogue sandbox modeling is a tool to simulate deformation style and structural evolution of sedimentary basins. The initial goal is to test what is the effect of inherited and crustal structures on the propagation, evolution, and final geometry of major strike-slip faults at the boundary between two tectonic plates. For this purpose, we have undertaken a series of analogue models to validate and reproduce the structures of the Levant Fracture System, a major NNE-SSW sinistral strike-slip fault forming the boundary between the Arabian and African plates. Onshore observations and recent high quality 3D seismic data in the Levant Basin offshore Lebanon demonstrated that Mesozoic ENE striking normal faults were reactivated into dextral strike-slip faults during the Late Miocene till present day activity of the plate boundary which shows a major restraining bend in Lebanon with a ~ 30°clockwise rotation in its trend. Experimental parameters consisted of a silicone layer at the base simulating the ductile crust, overlain by intercalated quartz sand and glass sand layers. Pre-existing structures were simulated by creating a graben in the silicone below the sand at an oblique (>60°) angle to the main throughgoing strike-slip fault. The latter contains a small stepover at depth to create transpression during sinistral strike-slip movement and consequently result in mountain building similarly to modern day Lebanon. Strike-slip movement and compression were regulated by steady-speed computer-controlled engines and the model was scanned using a CT-scanner continuously while deforming to have a final 4D model of the system. Results showed that existing normal faults were reactivated into dextral strike-slip faults as the sinistral movement between the two plates accumulated. Notably, the resulting restraining bend is asymmetric and segmented into two different compartments with differing geometries. One compartment shows a box fold anticline, while the second shows an

  17. Analogue modelling of a reactivated, basement controlled strike-slip zone, Sierra de Albarracín, Spain: application of sandbox modelling to polyphase deformation

    NARCIS (Netherlands)

    Merten, S.; Smit, W.G.; Nieuwland, D.A.; Rondeel, H.E.

    2006-01-01

    This paper presents the results of an analogue modelling study on the reactivation of Riedel shears generated by basement-induced sinistral strike-slip faulting. It is based on a natural example in the Sierra de Albarracín, Iberian Range (Spain). The area has a polyphase deformation history, defined

  18. Fault structure and kinematics of the Long Valley Caldera region, California, revealed by high-accuracy earthquake hypocenters and focal mechanism stress inversions

    Science.gov (United States)

    Prejean, Stephanie; Ellsworth, William L.; Zoback, Mark; Waldhauser, Felix

    2002-01-01

    We have determined high-resolution hypocenters for 45,000+ earthquakes that occurred between 1980 and 2000 in the Long Valley caldera area using a double-difference earthquake location algorithm and routinely determined arrival times. The locations reveal numerous discrete fault planes in the southern caldera and adjacent Sierra Nevada block (SNB). Intracaldera faults include a series of east/west-striking right-lateral strike-slip faults beneath the caldera's south moat and a series of more northerly striking strike-slip/normal faults beneath the caldera's resurgent dome. Seismicity in the SNB south of the caldera is confined to a crustal block bounded on the west by an east-dipping oblique normal fault and on the east by the Hilton Creek fault. Two NE-striking left-lateral strike-slip faults are responsible for most seismicity within this block. To understand better the stresses driving seismicity, we performed stress inversions using focal mechanisms with 50 or more first motions. This analysis reveals that the least principal stress direction systematically rotates across the studied region, from NE to SW in the caldera's south moat to WNW-ESE in Round Valley, 25 km to the SE. Because WNW-ESE extension is characteristic of the western boundary of the Basin and Range province, caldera area stresses appear to be locally perturbed. This stress perturbation does not seem to result from magma chamber inflation but may be related to the significant (???20 km) left step in the locus of extension along the Sierra Nevada/Basin and Range province boundary. This implies that regional-scale tectonic processes are driving seismic deformation in the Long Valley caldera.

  19. A Physical Analog Model of Strike-Slip Faulting for Model-Based Inquiry in the Classroom

    Science.gov (United States)

    Curren, I. S.; Glesener, G.

    2013-12-01

    Geoscience educators often use qualitative physical analog models to demonstrate natural processes; while these are effective teaching tools, they often neglect the fundamental scientific practices that make up the core of scientific work. Physical analog models with dynamic properties that can be manipulated and measured quantitatively in real-time, on the other hand, can give students the opportunity to explore, observe and empirically test their own ideas and hypotheses about the relevant target concepts within a classroom setting. Providing classroom content for inquiry, such as a hands-on physical analog model, which fosters students' production and refinement of their mental models in participatory and discursive activities have been argued by many education researchers to help students build a deeper understanding of science and scientific reasoning. We present a physical analog model that was originally developed by UCLA's Modeling and Educational Demonstrations Laboratory (MEDL) for the purpose of engaging students in the study of elastic rebound on a strike-slip fault; it was later modified to accommodate research of complex tectonic processes associated with strike-slip faulting, which are currently debated by scientists in both the geology and geophysics disciplines. During experimentation, it became clear that this new design could be used as a relevant resource for inquiry from which students would be able to make and discuss real-time empirical measurements and observations to help them infer causal accounts of theoretical and/or unobservable dynamic processes within the Earth's crust. In our poster session, we will: 1) demonstrate the physical analog model; 2) describe various real-time data collection tools, as well as quantitative methods students can use to process their data; and 3) describe the surficial, structural and relational similarities between the physical analog model and the target concepts intended for students to explore in the

  20. The geometry of pull-apart basins in the southern part of Sumatran strike-slip fault zone

    Science.gov (United States)

    Aribowo, Sonny

    2018-02-01

    Models of pull-apart basin geometry have been described by many previous studies in a variety tectonic setting. 2D geometry of Ranau Lake represents a pull-apart basin in the Sumatran Fault Zone. However, there are unclear geomorphic traces of two sub-parallel overlapping strike-slip faults in the boundary of the lake. Nonetheless, clear geomorphic traces that parallel to Kumering Segment of the Sumatran Fault are considered as inactive faults in the southern side of the lake. I demonstrate the angular characteristics of the Ranau Lake and Suoh complex pull-apart basins and compare with pull-apart basin examples from published studies. I use digital elevation model (DEM) image to sketch the shape of the depression of Ranau Lake and Suoh Valley and measure 2D geometry of pull-apart basins. This study shows that Ranau Lake is not a pull-apart basin, and the pull-apart basin is actually located in the eastern side of the lake. Since there is a clear connection between pull-apart basin and volcanic activity in Sumatra, I also predict that the unclear trace of the pull-apart basin near Ranau Lake may be covered by Ranau Caldera and Seminung volcanic products.

  1. Dynamic response to strike-slip tectonic control on the deposition and evolution of the Baranof Fan, Gulf of Alaska

    Science.gov (United States)

    Walton, Maureen A. L.; Gulick, Sean P. S.; Reece, Robert S.; Barth, Ginger A.; Christeson, Gail L.; VanAvendonk, Harm J.

    2014-01-01

    The Baranof Fan is one of three large deep-sea fans in the Gulf of Alaska, and is a key component in understanding large-scale erosion and sedimentation patterns for southeast Alaska and western Canada. We integrate new and existing seismic reflection profiles to provide new constraints on the Baranof Fan area, geometry, volume, and channel development. We estimate the fan’s area and total sediment volume to be ∼323,000 km2 and ∼301,000 km3, respectively, making it among the largest deep-sea fans in the world. We show that the Baranof Fan consists of channel-levee deposits from at least three distinct aggradational channel systems: the currently active Horizon and Mukluk channels, and the waning system we call the Baranof channel. The oldest sedimentary deposits are in the northern fan, and the youngest deposits at the fan’s southern extent; in addition, the channels seem to avulse southward consistently through time. We suggest that Baranof Fan sediment is sourced from the Coast Mountains in southeastern Alaska, transported offshore most recently via fjord to glacial sea valley conduits. Because of the translation of the Pacific plate northwest past sediment sources on the North American plate along the Queen Charlotte strike-slip fault, we suggest that new channel formation, channel beheadings, and southward-migrating channel avulsions have been influenced by regional tectonics. Using a simplified tectonic reconstruction assuming a constant Pacific plate motion of 4.4 cm/yr, we estimate that Baranof Fan deposition initiated ca. 7 Ma.

  2. (Plio-)Pleistocene alluvial-lacustrine basin infill evolution in a strike-slip active zone (Northern Andes, Western-Central Cordilleras, Colombia)

    OpenAIRE

    SUTER, F.; NEUWERTH, R.; GORIN, G.; GUZMÁN, C.

    2009-01-01

    The (Plio)-Pleistocene Zarzal Formation was deposited in the Cauca Depression and Quindío-Risaralda Basin between the Western and Central Cordilleras (Northern Andes). This area is structurally located on the transcurrent Romeral Fault System (RFS). Because of the interaction between the Nazca plate and the Chocó-Panamá block (an active indenter), the RFS strike-slip component changes direction around the study zone (dextral in the south, senestral in the north). Zarzal sediments are the olde...

  3. Evolution of the stress fields in the Zagros Foreland Folded Belt using focal mechanisms and kinematic analyses: the case of the Fars salient, Iran

    Science.gov (United States)

    Sarkarinejad, Khalil; Zafarmand, Bahareh; Oveisi, Behnam

    2018-03-01

    The NW-SE trending Zagros orogenic belt was initiated during the convergence of the Afro-Arabian continent and the Iranian microcontinent in the Late Cretaceous. Ongoing convergence is confirmed by intense seismicity related to compressional stresses collision-related in the Zagros orogenic belt by reactivation of an early extensional faulting to latter compressional segmented strike-slip and dip-slip faulting. These activities are strongly related either to the deep-seated basement fault activities (deep-seated earthquakes) underlies the sedimentary cover or gently dipping shallow-seated décollement horizon of the rheological weak rocks of the infra-Cambrian Hormuz salt. The compressional stress regimes in the different units play an important role in controlling the stress conditions between the different units within the sedimentary cover and basement. A significant set of nearly N-S trending right-lateral strike-slip faults exists throughout the study area in the Fars area in the Zagros Foreland Folded Belt. Fault-slip and focal mechanism data were analyzed using the stress inversion method to reconstruct the paleo and recent stress conditions. The results suggest that the current direction of maximum principal stress averages N19°E, with N38°E that for the past from Cretaceous to Tertiary (although a few sites on the Kar-e-Bass fault yield a different direction). The results are consistent with the collision of the Afro-Arabian continent and the Iranian microcontinent. The difference between the current and paleo-stress directions indicates an anticlockwise rotation in the maximum principle stress direction over time. This difference resulted from changes in the continental convergence path, but was also influenced by the local structural evolution, including the lateral propagation of folds and the presence of several local décollement horizons that facilitated decoupling of the deformation between the basement and the sedimentary cover. The obliquity of

  4. Oblique strike-slip motion off the Southeastern Continental Margin of India: Implication for the separation of Sri Lanka from India

    Science.gov (United States)

    Desa, Maria Ana; Ismaiel, Mohammad; Suresh, Yenne; Krishna, Kolluru Sree

    2018-05-01

    The ocean floor in the Bay of Bengal has evolved after the breakup of India from Antarctica since the Early Cretaceous. Recent geophysical investigations including updated satellite derived gravity map postulated two phases for the tectonic evolution of the Bay of Bengal, the first phase of spreading occurred in the NW-SE direction forming its Western Basin, while the second phase occurred in the N-S direction resulting in its Eastern Basin. Lack of magnetic data along the spreading direction in the Western Basin prompted us to acquire new magnetic data along four tracks (totaling ∼3000 km) to validate the previously identified magnetic anomaly picks. Comparison of the synthetic seafloor spreading model with the observed magnetic anomalies confirmed the presence of Mesozoic anomalies M12n to M0 in the Western Basin. Further, the model suggests that this spreading between India and Antarctica took place with half-spreading rates of 2.7-4.5 cm/yr. The trend of the fracture zones in the Western Basin with respect to that of the Southeastern Continental Margin of India (SCMI) suggests that SCMI is an oblique transform margin with 37° obliquity. Further, the SCMI consists of two oblique transform segments separated by a small rift segment. The strike-slip motion along the SCMI is bounded by the rift segments of the Northeastern Continental Margin of India and the southern margin of Sri Lanka. The margin configuration and fracture zones inferred in its conjugate Western Enderby Basin, East Antarctica helped in inferring three spreading corridors off the SCMI in the Western Basin of the Bay of Bengal. Detailed grid reconstruction models traced the oblique strike-slip motion off the SCMI since M12n time. The strike-slip motion along the short northern transform segment ended by M11n time. The longer transform segment, found east of Sri Lanka lost its obliquity and became a pure oceanic transform fault by M0 time. The eastward propagation of the Africa

  5. Stress sensitivity of fault seismicity: A comparison between limited-offset oblique and major strike-slip faults

    Science.gov (United States)

    Parsons, T.; Stein, R.S.; Simpson, R.W.; Reasenberg, P.A.

    1999-01-01

    We present a new three-dimensional inventory of the southern San Francisco Bay area faults and use it to calculate stress applied principally by the 1989 M = 7.1 Loma Prieta earthquake and to compare fault seismicity rates before and after 1989. The major high-angle right-lateral faults exhibit a different response to the stress change than do minor oblique (right-lateral/thrust) faults. Seismicity on oblique-slip faults in the southern Santa Clara Valley thrust belt increased where the faults were unclamped. The strong dependence of seismicity change on normal stress change implies a high coefficient of static friction. In contrast, we observe that faults with significant offset (>50-100 km) behave differently; microseismicity on the Hayward fault diminished where right-lateral shear stress was reduced and where it was unclamped by the Loma Prieta earthquake. We observe a similar response on the San Andreas fault zone in southern California after the Landers earthquake sequence. Additionally, the offshore San Gregorio fault shows a seismicity rate increase where right-lateral/oblique shear stress was increased by the Loma Prieta earthquake despite also being clamped by it. These responses are consistent with either a low coefficient of static friction or high pore fluid pressures within the fault zones. We can explain the different behavior of the two styles of faults if those with large cumulative offset become impermeable through gouge buildup; coseismically pressurized pore fluids could be trapped and negate imposed normal stress changes, whereas in more limited offset faults, fluids could rapidly escape. The difference in behavior between minor and major faults may explain why frictional failure criteria that apply intermediate coefficients of static friction can be effective in describing the broad distributions of aftershocks that follow large earthquakes, since many of these events occur both inside and outside major fault zones.

  6. Excitation of tsunami by a pure strike-slip earthquake. ; Izu Oshima kinkai earthquake tsunami on Feb. 20, 1990. Yokozure danso jishin ni yoru tsunami no reiki. ; 1990 nen 2 gatsu 20 nichi Izu Oshima kinkai jishin tsunami

    Energy Technology Data Exchange (ETDEWEB)

    Abe, K. (Nippon Dental University, Tokyo (Japan). Niigata Junior College); Okada, M. (Meteorological Research Institute, Tsukuba (Japan))

    1993-06-24

    A numerical experiment was performed to reproduce the tsunami from the Izu-Oshima Kinkai Earthquake which occurred on February 20, 1990, using a tsunami excited by a pure strike-slip fault. An existence of a vertical fault with a length of 15 km and a width of 12 km was hypothesized in the south-north direction on the ocean bottom around the focal region. Then, a tsunami was assumed to have been excited when the fault was given a side-slip movement to create discrepancies of 1 m in the fault. Water level change for one hour after onset of the tsunami was calculated in one-second interval in each unit square with a side length of 1 km over an ocean area of 200 km from east to west and 150 km from north to south centering on the wave source. The results obtained from the calculation were harmonious with tsunami waveforms observed at five stations in the subject region and their spectral analytic results. Reproduced were the two predominant frequencies commonly observed at more than two stations, and difference in predominant cycles that appear according to azimuths of the observation points to the epicenter. These facts endorse the reasonability of the above hypothesis. 9 refs., 11 figs.

  7. Late Quaternary strike-slip along the Taohuala Shan-Ayouqi fault zone and its tectonic implications in the Hexi Corridor and the southern Gobi Alashan, China

    Science.gov (United States)

    Yu, Jing-xing; Zheng, Wen-jun; Zhang, Pei-zhen; Lei, Qi-yun; Wang, Xu-long; Wang, Wei-tao; Li, Xin-nan; Zhang, Ning

    2017-11-01

    The Hexi Corridor and the southern Gobi Alashan are composed of discontinuous a set of active faults with various strikes and slip motions that are located to the north of the northern Tibetan Plateau. Despite growing understanding of the geometry and kinematics of these active faults, the late Quaternary deformation pattern in the Hexi Corridor and the southern Gobi Alashan remains controversial. The active E-W trending Taohuala Shan-Ayouqi fault zone is located in the southern Gobi Alashan. Study of the geometry and nature of slip along this fault zone holds crucial value for better understanding the regional deformation pattern. Field investigations combined with high-resolution imagery show that the Taohuala Shan fault and the E-W trending faults within the Ayouqi fault zone (F2 and F5) are left-lateral strike-slip faults, whereas the NW or WNW-trending faults within the Ayouqi fault zone (F1 and F3) are reverse faults. We collected Optically Stimulated Luminescence (OSL) and cosmogenic exposure age dating samples from offset alluvial fan surfaces, and estimated a vertical slip rate of 0.1-0.3 mm/yr, and a strike-slip rate of 0.14-0.93 mm/yr for the Taohuala Shan fault. Strata revealed in a trench excavated across the major fault (F5) in the Ayouqi fault zone and OSL dating results indicate that the most recent earthquake occurred between ca. 11.05 ± 0.52 ka and ca. 4.06 ± 0.29 ka. The geometry and kinematics of the Taohuala Shan-Ayouqi fault zone enable us to build a deformation pattern for the entire Hexi Corridor and the southern Gobi Alashan, which suggest that this region experiences northeastward oblique extrusion of the northern Tibetan Plateau. These left-lateral strike-slip faults in the region are driven by oblique compression but not associated with the northeastward extension of the Altyn Tagh fault.

  8. Silurian to Devonian magmatism, molybdenite mineralization, regional exhumation and brittle strike-slip deformation along the Loch Shin Line, NW Scotland

    OpenAIRE

    Holdsworth, R.; Dempsey, E.; Selby, D.; Darling, James Richard; Feely, M.; Costanzo, A.; Strachan, Robin A; Waters, P.; Finlay, A.J.

    2015-01-01

    The Loch Shin Line is a geological–geophysical lineament associated with a zone of mantle-derived appinites, granites and strike-slip faulting that runs NW–SE across the Moine Nappe, northern Scotland. U–Pb zircon and Re–Os molybdenite dating of the Loch Shin and Grudie plutons, which lie immediately SW of the NW–SE Loch Shin–Strath Fleet fault system, yield c. 427–430 Ma ages that overlap within error. They also coincide with previously obtained U–Pb zircon ages for the Rogart pluton, which ...

  9. The Evolution from Late Miocene West Salton Detachment Faulting to Cross-Cutting Pleistocene Oblique Strike-Slip Faults in the SW Salton Trough, Southern California

    OpenAIRE

    Steely, Alexander N.

    2006-01-01

    Field studies in the southwest Salton Trough between Yaqui Ridge and Borrego Mountain show that the West Salton detachment fault was active during the Pliocene and may have initiated during the latest Miocene. At Yaqui Ridge dominantly east-directed extension is recorded by slickenlines on the NW-striking detachment fault, and shows that the fault is actually a low-angle dextral oblique strike-slip fault. Crustal inheritance is responsible for the position of the fault at Yaqui Ridge, which r...

  10. Seismicity, focal mechanisms, and stress distribution in the Tres Virgenes volcanic and geothermal region, Baja California Sur, Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Wong, Victor; Munguia, Luis [Centro de Investigacion Cientifica y de Educacion Superior de Ensenada (Mexico)

    2006-01-15

    In October 1993 we carried out a seismic monitoring in the Tres Virgenes volcanic region in order to record the background seismicity associated with the volcanic structures, the geothermal field and the tectonic features of the area. Hypocenters for 257 microearthquakes were located in the volcanic edifices and along the northwest right-lateral, strike-slip La Virgen fault. Focal depths range from close to the Earth surface to about 8 km. Shallow depths occur mainly in the volcanic edifices. Deeper seismic events occurred outside the volcanic area. The duration magnitudes of the located microearthquakes range between 1 and 3. The Vp/Vs ratio and the low-Q values estimated suggest heterogeneous material properties in the volcanic structures mainly toward the El Azufre fault and the El Aguajito Caldera, where hydrothermal activity has been reported. The P- and T-axes of focal mechanisms for 90 microearthquakes suggest that the region is under N-S compression and E-W extension, in agreement with the regional tectonic stress field of the NW-SE right-lateral strike-slip transform fault system of the Gulf of California. [Spanish] En octubre de 1993 se llevo a cabo un monitoreo sismico en la region volcanica Las Tres Virgenes con el proposito de registrar la actividad sismica asociada a las estructuras volcanicas, al campo geotermico y a la tectonica local. Se localizaron 257 microsismos con hipocentros en los edificios volcanicos y a lo largo de la falla de rumbo, lateral derecha conocida como falla La Virgen. La profundidad focal de los sismos varia desde los muy cercanos a la superficie de la Tierra hasta los 8 km. Las profundidades someras ocurren principalmente en los edificios volcanicos. Los sismos mas profundos ocurren fuera del area volcanica. La magnitud de duracion de los microsismos localizados varia entre 1 y 3. La razon Vp/Vs y los valores bajos de Q que se estimaron en la zona sugieren un material con propiedades heterogeneas bajo las estructuras

  11. Structural analysis of S-wave seismics around an urban sinkhole: evidence of enhanced dissolution in a strike-slip fault zone

    Science.gov (United States)

    Wadas, Sonja H.; Tanner, David C.; Polom, Ulrich; Krawczyk, Charlotte M.

    2017-12-01

    In November 2010, a large sinkhole opened up in the urban area of Schmalkalden, Germany. To determine the key factors which benefited the development of this collapse structure and therefore the dissolution, we carried out several shear-wave reflection-seismic profiles around the sinkhole. In the seismic sections we see evidence of the Mesozoic tectonic movement in the form of a NW-SE striking, dextral strike-slip fault, known as the Heßleser Fault, which faulted and fractured the subsurface below the town. The strike-slip faulting created a zone of small blocks ( sinkholes and dissolution-induced depressions. Since the processes are still ongoing, the occurrence of a new sinkhole cannot be ruled out. This case study demonstrates how S-wave seismics can characterize a sinkhole and, together with geological information, can be used to study the processes that result in sinkhole formation, such as a near-surface fault zone located in soluble rocks. The more complex the fault geometry and interaction between faults, the more prone an area is to sinkhole occurrence.

  12. States of stress and slip partitioning in a continental scale strike-slip duplex: Tectonic and magmatic implications by means of finite element modeling

    Science.gov (United States)

    Iturrieta, Pablo Cristián; Hurtado, Daniel E.; Cembrano, José; Stanton-Yonge, Ashley

    2017-09-01

    Orogenic belts at oblique convergent subduction margins accommodate deformation in several trench-parallel domains, one of which is the magmatic arc, commonly regarded as taking up the margin-parallel, strike-slip component. However, the stress state and kinematics of volcanic arcs is more complex than usually recognized, involving first- and second-order faults with distinctive slip senses and mutual interaction. These are usually organized into regional scale strike-slip duplexes, associated with both long-term and short-term heterogeneous deformation and magmatic activity. This is the case of the 1100 km-long Liquiñe-Ofqui Fault System in the Southern Andes, made up of two overlapping margin-parallel master faults joined by several NE-striking second-order faults. We present a finite element model addressing the nature and spatial distribution of stress across and along the volcanic arc in the Southern Andes to understand slip partitioning and the connection between tectonics and magmatism, particularly during the interseismic phase of the subduction earthquake cycle. We correlate the dynamics of the strike-slip duplex with geological, seismic and magma transport evidence documented by previous work, showing consistency between the model and the inferred fault system behavior. Our results show that maximum principal stress orientations are heterogeneously distributed within the continental margin, ranging from 15° to 25° counter-clockwise (with respect to the convergence vector) in the master faults and 10-19° clockwise in the forearc and backarc domains. We calculate the stress tensor ellipticity, indicating simple shearing in the eastern master fault and transpressional stress in the western master fault. Subsidiary faults undergo transtensional-to-extensional stress states. The eastern master fault displays slip rates of 5 to 10 mm/yr, whereas the western and subsidiary faults show slips rates of 1 to 5 mm/yr. Our results endorse that favorably oriented

  13. The 2015 M7.2 Sarez, Central Pamir, Earthquake And The Importance Of Strike-Slip Faulting In The Pamir Interior: Insights From Geodesy And Field Observations

    Science.gov (United States)

    Metzger, Sabrina; Schurr, Bernd; Ratschbacher, Lothar; Schöne, Tilo; Kufner, Sofia-Katerina; Zhang, Yong; Sudhaus, Henriette

    2017-04-01

    The Pamir mountain range, located in the Northwest of the India-Asia collision zone, accommodates approximately one third of the northward advance of the Indian continent at this longitude (i. e. ˜34 mm/yr) mostly by shortening at its northern thrust system. Geodetic and seismic data sets reveal here a narrow zone of high deformation and M7+ earthquakes of mostly thrust type with some dextral strike-slip faulting observed, too. The Pamir interior shows sinistral strike-slip and normal faulting indicating north-south compression and east-west extension. In this tectonic setting the two largest instrumentally recorded earthquakes, the M7+ 1911 and 2015 earthquake events in the central Pamir occurred with left-lateral shear along a NE-SW rupture plane. We present the co-seismic deformation field of the 2015 earthquake observed by radar satellite interferometry (InSAR), SAR amplitude pixel offsets and high-rate Global Positioning System (GPS). The InSAR and pixel offset results suggest a 50+ km long rupture with sinistral fault offsets at the surface of more than 2 m on a yet unmapped fault trace of the Sarez Karakul Fault System (SKFS). A distributed slip model with a data-driven slip patch resolution yields a sub-vertical fault plane with a strike of N39.5 degrees and a rupture area of ˜80 x 40 km with a maximum slip of 2 m in the upper 10 km of the crust near the surface rupture. Field observations collected some nine months after the earthquake confirm the rupture mechanism, surface trace location and fault offset measurements as constrained by geodetic data. Diffuse deformation was observed across a 1-2 km wide zone, hosting primary fractures sub-parallel to the rupture strike with offsets of 2 m and secondary, en echelon fractures including Riedel shears and hybrid fractures often related to gravitational mass movements. The 1911 and 2015 earthquakes demonstrate the importance of sinistral strike-slip faulting on the SKFS, contributing both to shear between the

  14. Rupture model of the 2015 M7.2 Sarez, Central Pamir, earthquake and the importance of strike-slip faulting in the Pamir interior

    Science.gov (United States)

    Metzger, S.; Schurr, B.; Schoene, T.; Zhang, Y.; Sudhaus, H.

    2016-12-01

    The Pamir mountain range, located in the Northwest of the India-Asia collision zone, accommodates approximately one third of the northward advance of the Indian continent at this longitude (i.e. 34 mm/yr) mostly by shortening at its northern thrust system. Geodetic and seismic data sets reveal here a narrow zone of high deformation and M7+ earthquakes of mostly thrust type with some dextral strike-slip faulting observed, too. The Pamir interior shows sinistral strike-slip and normal faulting indicating north-south compression and east-west extension. In this tectonic setting the two largest instrumentally recorded earthquakes, the M7+ 1911 and 2015 earthquake events in the central Pamir occurred with left-lateral shear along a NE-SW rupture plane. We present the co-seismic deformation field of the 2015 earthquake observed by Radar satellite interferometry (InSAR), SAR amplitude offsets and high-rate Global Positioning System (GPS). The InSAR and offset results reveal that the earthquake created a 50 km long surface rupture with maximum left-lateral offsets of more than two meters on a yet unmapped fault trace of the Sarez Karakul Fault System (SKFS). We further derive a distributed slip-model including a thorough model parameter uncertainty study. Using a two-step approach to first find the optimal rupture geometry and then invert for slip on discrete patches, we show that a data-driven patch resolution produces yields a better representation of the near-surface slip and an increased slip precision than a uniform patch approach without increasing the number of parameters and thus calculation time. Our best-fit model yields a sub-vertical fault plane with a strike of N39.5 degrees and a rupture area of 80 x 40 km2 with a maximum slip of 2 meters in the upper 10 km of the crust near the surface rupture. The 1911 and 2015 earthquakes demonstrate the importance of sinistral strike-slip faulting on the SKFS, contributing both to shear between the western and eastern

  15. Insights on the seismotectonics of the western part of northern Calabria (southern Italy) by integrated geological and geophysical data: Coexistence of shallow extensional and deep strike-slip kinematics

    Science.gov (United States)

    Ferranti, L.; Milano, G.; Pierro, M.

    2017-11-01

    We assess the seismotectonics of the western part of the border area between the Southern Apennines and Calabrian Arc, centered on the Mercure extensional basin, by integrating recent seismicity with a reconstruction of the structural frame from surface to deep crust. The analysis of low-magnitude (ML ≤ 3.5) events occurred in the area during 2013-2017, when evaluated in the context of the structural model, has revealed an unexpected complexity of seismotectonics processes. Hypocentral distribution and kinematics allow separating these events into three groups. Focal mechanisms of the shallower (kinematics. These results are consistent with the last kinematic event recorded on outcropping faults, and with the typical depth and kinematics of normal faulting earthquakes in the axial part of southern Italy. By contrast, intermediate ( 9-17 km) and deep ( 17-23 km) events have fault plane solutions characterized by strike- to reverse-oblique slip, but they differ from each other in the orientation of the principal axes. The intermediate events have P axes with a NE-SW trend, which is at odds with the NW-SE trend recorded by strike-slip earthquakes affecting the Apulia foreland plate in the eastern part of southern Italy. The intermediate events are interpreted to reflect reactivation of faults in the Apulia unit involved in thrust uplift, and appears aligned along an WNW-ESE trending deep crustal, possibly lithospheric boundary. Instead, deep events beneath the basin, which have P-axis with a NW-SE trend, hint to the activity of a deep overthrust of the Tyrrhenian back-arc basin crust over the continental crust of the Apulia margin, or alternatively, to a tear fault in the underthrust Apulia plate. Results of this work suggest that extensional faulting, as believed so far, does not solely characterizes the seismotectonics of the axial part of the Southern Apennines.

  16. Analogue modelling on the interaction between shallow magma intrusion and a strike-slip fault: Application on the Middle Triassic Monzoni Intrusive Complex (Dolomites, Italy)

    Science.gov (United States)

    Michail, Maria; Coltorti, Massimo; Gianolla, Piero; Riva, Alberto; Rosenau, Matthias; Bonadiman, Costanza; Galland, Olivier; Guldstrand, Frank; Thordén Haug, Øystein; Rudolf, Michael; Schmiedel, Tobias

    2017-04-01

    The southwestern part of the Dolomites in Northern Italy has undergone a short-lived Ladinian (Middle Triassic) tectono-magmatic event, forming a series of significant magmatic features. These intrusive bodies deformed and metamorphosed the Permo-Triassic carbonate sedimentary framework. In this study we focus on the tectono-magmatic evolution of the shallow shoshonitic Monzoni Intrusive Complex of this Ladinian event (ca 237 Ma), covering an area of 20 km^2. This NW-SE elongated intrusive structure (5 km length) shows an orogenic magmatic affinity which is in contrast to the tectonic regime at the time of intrusion. Strain analysis shows anorogenic transtensional displacement in accordance with the ENE-WSW extensional pattern in the central Dolomites during the Ladinian. Field interpretations led to a detailed description of the regional stratigraphic sequence and the structural features of the study area. However, the geodynamic context of this magmatism and the influence of the inherited strike-slip fault on the intrusion, are still in question. To better understand the specific natural prototype and the general mechanisms of magma emplacement in tectonically active areas, we performed analogue experiments defined by, but not limited to, first order field observations. We have conducted a systematic series of experiments in different tectonic regimes (static conditions, strike-slip, transtension). We varied the ratio of viscous to brittle stresses between magma and country rock, by injecting Newtonian fluids both of high and low viscosity (i.e. silicone oil/vegetable oil) into granular materials of varying cohesion (sand, silica flour, glass beads). The evolving surface and side view of the experiments were monitored by photogrammetric techniques for strain analyses and topographic evolution. In our case, the combination of the results from field and analogue experiments brings new insights regarding the tectonic regime, the geometry of the intrusive body, and

  17. Structural analysis of S-wave seismics around an urban sinkhole: evidence of enhanced dissolution in a strike-slip fault zone

    Directory of Open Access Journals (Sweden)

    S. H. Wadas

    2017-12-01

    Full Text Available In November 2010, a large sinkhole opened up in the urban area of Schmalkalden, Germany. To determine the key factors which benefited the development of this collapse structure and therefore the dissolution, we carried out several shear-wave reflection-seismic profiles around the sinkhole. In the seismic sections we see evidence of the Mesozoic tectonic movement in the form of a NW–SE striking, dextral strike-slip fault, known as the Heßleser Fault, which faulted and fractured the subsurface below the town. The strike-slip faulting created a zone of small blocks ( < 100 m in size, around which steep-dipping normal faults, reverse faults and a dense fracture network serve as fluid pathways for the artesian-confined groundwater. The faults also acted as barriers for horizontal groundwater flow perpendicular to the fault planes. Instead groundwater flows along the faults which serve as conduits and forms cavities in the Permian deposits below ca. 60 m depth. Mass movements and the resulting cavities lead to the formation of sinkholes and dissolution-induced depressions. Since the processes are still ongoing, the occurrence of a new sinkhole cannot be ruled out. This case study demonstrates how S-wave seismics can characterize a sinkhole and, together with geological information, can be used to study the processes that result in sinkhole formation, such as a near-surface fault zone located in soluble rocks. The more complex the fault geometry and interaction between faults, the more prone an area is to sinkhole occurrence.

  18. The 2015 Mw7.2 Sarez Strike-Slip Earthquake in the Pamir Interior: Response to the Underthrusting of India's Western Promontory

    Science.gov (United States)

    Metzger, Sabrina; Schurr, Bernd; Ratschbacher, Lothar; Sudhaus, Henriette; Kufner, Sofia-Katerina; Schöne, Tilo; Zhang, Yong; Perry, Mason; Bendick, Rebecca

    2017-11-01

    The Pamir orogen, Central Asia, is the result of the ongoing northward advance of the Indian continent causing shortening inside Asia. Geodetic and seismic data place the most intense deformation along the northern rim of the Pamir, but the recent 7 December 2015, Mw7.2 Sarez earthquake occurred in the Pamir's interior. We present a distributed slip model of this earthquake using coseismic geodetic data and postseismic field observations. The earthquake ruptured an ˜80 km long, subvertical, sinistral fault consisting of three right-stepping segments from the surface to ˜30 km depth with a maximum slip of three meters in the upper 10 km of the crust. The coseismic slip model agrees well with en échelon secondary surface breaks that are partly influenced by liquefaction-induced mass movements. These structures reveal up to 2 m of sinistral offset along the northern, low-offset segment of modeled rupture. The 2015 event initiated close to the presumed epicenter of the 1911 Mw˜7.3 Lake Sarez earthquake, which had a similar strike-slip mechanism. These earthquakes highlight the importance of NE trending sinistral faults in the active tectonics of the Pamir. Strike-slip deformation accommodates shear between the rapidly northward moving eastern Pamir and the Tajik basin in the west and is part of the westward (lateral) extrusion of thickened Pamir plateau crust into the Tajik basin. The Sarez-Karakul fault system and the two large Sarez earthquakes likely are crustal expressions of the underthrusting of the northwestern leading edge of the Indian mantle lithosphere beneath the Pamir.

  19. The last interglacial period at Guantanamo Bay, Cuba and an estimate of late Quaternary tectonic uplift rate in a strike-slip regime

    Science.gov (United States)

    Schweig, E. S.; Muhs, D. R.; Simmons, K. R.; Halley, R. B.

    2015-12-01

    Guantanamo Bay, Cuba is an area dominated by a strike-slip tectonic regime and is therefore expected to have very low Quaternary uplift rates. We tested this hypothesis by study of an unusually well preserved emergent reef terrace around the bay. Up to 12 m of unaltered, growth-position reef corals are exposed at about 40 sections examined around ˜40 km of coastline. Maximum reef elevations in the protected, inner part of the bay are ˜11-12 m, whereas outer-coast shoreline angles of wave-cut benches are as high as ˜14 m. Fifty uranium-series analyses of unrecrystallized corals from six localities yield ages ranging from ˜134 ka to ˜115 ka, when adjusted for small biases due to slightly elevated initial 234U/238U values. Thus, ages of corals correlate this reef to the peak of the last interglacial period, marine isotope stage (MIS) 5.5. Previously, we dated the Key Largo Limestone to the same high-sea stand in the tectonically stable Florida Keys. Estimates of paleo-sea level during MIS 5.5 in the Florida Keys are ~6.6 to 8.3 m above present. Assuming a similar paleo-sea level in Cuba, this yields a long-term tectonic uplift rate of 0.04-0.06 m/ka over the past ~120 ka. This estimate supports the hypothesis that the tectonic uplift rate should be low in this strike-slip regime. Nevertheless, on the southeast coast of Cuba, east of our study area, we have observed flights of multiple marine terraces, suggesting either (1) a higher uplift rate or (2) an unusually well-preserved record of pre-MIS 5.5 terraces not observed at Guantanamo Bay.

  20. Analogue modelling of strike-slip fault propagation across a rheological/morphological crustal anisotropy: implications for the morphotectonic evolution of the Gloria Fault - Tore Madeira Rise area in NE Atlantic.

    Science.gov (United States)

    Tomás, Ricardo; Rosas, Filipe M.; Duarte, João C.; Terrinha, Pedro; Kullberg, Maria C.; Almeida, Jaime; Barata, Frederico; Carvalho, Bruno; Almeida, Pedro

    2015-04-01

    The Gloria Fault (GF) marks the E-W dextral transcurrent plate boundary between Eurasia and Africa in NE Atlantic, displaying complying high magnitude (historical and instrumental) seismic activity (e.g. M=7.1 in 1939 and M=8.4 in 1941, Bufforn et al., 1988), and cutting across a NNE-SSW 1000 km long bathymetric ridge: the so called Tore-Madeira Rise - TMR (rising in average 3km above the abyssal plain). The precise origin and tectono-magmatic evolution of the TMR is still not fully understood, although reported wide-angle refraction data points to a rheological configuration comprising an isostatically compensated thickened oceanic crust, possibly formed during a period of high accretion in the Mid-Atlantic Ridge (Pierce and Barton, 1991). Widespread evidence for volcanic activity has also been recognized, spanning from late Cretaceous to Present (Geldmacher et al. 2006, Merle et al. 2009), noticeably with the most recent volcanism (~500 Ky) occurring as tectonically aligned volcanic plugs, distributed along the E-W tectonic trend of the GF-related structures. To better understand the complex interference at play in this key area between the tectonic structures (essentially determined by the Gloria Fault system), the present and past magmatic activity and the resulting seafloor morphology, a series of dynamically scaled analogue modelling experiments have been conceived and carried out. The main focus of this experimental work was to decipher the potential influence of a rheological vs. morphological anisotropy (accounting for the TMR) on the lateral propagation of a major right-lateral strike-slip fault (representing the GF). The preliminary comparison of the obtained experimental results with the natural morphotectonic pattern in the study area reveals, not only a strong tectonic control of the ongoing volcanism, manifested by the observed preferred directions of aligned volcanic plugs, but also a so far unsuspected deflection/distributed pattern of several

  1. 'Extra-regional' strike-slip fault systems in Chile and Alaska: the North Pacific Rim orogenic Stream vs. Beck's Buttress

    Science.gov (United States)

    Redfield, T. F.; Scholl, D. W.; Fitzgerald, P. G.

    2010-12-01

    The ~2000 km long Denali Fault System (DFS) of Alaska is an example of an extra-regional strike-slip fault system that terminates in a zone of widely-distributed deformation. The ~1200 km long Liquiñe-Ofqui Fault Zone (LOFZ) of Patagonia (southern Chile) is another. Both systems are active, having undergone large-magnitude seismic rupture is 2002 (DFS) and 2007 (LOFZ). Both systems appear to be long-lived: the DFS juxtaposes terranes that docked in at least early Tertiary time, whilst the central LOFZ appears to also record early Tertiary or Mesozoic deformation. Both fault systems comprise a relatively well-defined central zone where individual fault traces can be identified from topographic features or zones of deformed rock. In both cases the proximal and distal traces are much more diffuse tributary and distributary systems of individual, branching fault traces. However, since their inception the DFS and LOFZ have followed very different evolutionary paths. Copious Alaskan paleomagnetic data are consistent with vertical axis small block rotation, long-distance latitudinal translation, and a recently-postulated tectonic extrusion towards a distributary of subordinate faults that branch outward towards the Aleution subduction zone (the North Pacific Rim orogenic Stream; see Redfield et al., 2007). Paleomagnetic data from the LOFZ region are consistent with small block rotation but preclude statistically-significant latitudinal transport. Limited field data from the southernmost LOFZ suggest that high-angle normal and reverse faults dominate over oblique to strike-slip structures. Rather than the high-angle oblique 'slivering regime' of the southeasternmost DFS, the initiation of the LOFZ appears to occur across a 50 to 100 km wide zone of brittly-deformed granitic and gneissic rock characterized by bulk compression and vertical pathways of exhumation. In both cases, relative plate motions are consistent with the hypothetical style, and degree, of offset, leading

  2. Palaeopermeability anisotropies of a strike-slip fault damage zone: 3D Insights of quantitative fluid flow from µCT analysis.

    Science.gov (United States)

    Gomila, R.; Arancibia, G.; Nehler, M.; Bracke, R.; Morata, D.

    2017-12-01

    Fault zones and their related structural permeability are a key aspect in the migration of fluids through the continental crust. Therefore, the estimation of the hydraulic properties (palaeopermeability conditions; k) and the spatial distribution of the fracture mesh within the damage zone (DZ) are critical in the assessment of fault zones behavior for fluids. The study of the real spatial distribution of the veinlets of the fracture mesh (3D), feasible with the use of µCT analyses, is a first order factor to unravel both, the real structural permeability conditions of a fault-zone, and the validation of previous (and classical) estimations made in 2D analyses in thin-sections. This work shows the results of a fault-related fracture mesh and its 3D spatial distribution in the damage-zone of the Jorgillo Fault (JF), an ancient subvertical left-lateral strike-slip fault exposed in the Atacama Fault System in northern Chile. The JF is a ca. 20 km long NNW-striking strike-slip fault with sinistral displacement of ca. 4 km. The methodology consisted of drilling 5 mm vertically oriented plugs at several locations within the JF damage zone. Each specimen was scanned with an X-Ray µCT scanner, to assess the fracture mesh, with a voxel resolution of ca. 4.5 µm in the 3D reconstructed data. Tensor permeability modeling, using Lattice-Boltzmann Method, through the segmented microfracture mesh show GMkmin (geometric mean values) of 2.1x10-12 and 9.8x10-13 m2, and GMkmax of 6.4x10-12 and 2.1x10-12 m2. A high degree of anisotropy of the DZ permeability tensor both sides of the JF (eastern and western side, respectively) is observed, where the k values in the kmax plane are 2.4 and 1.9 times higher than the kmin direction at the time of fracture sealing. This style of anisotropy is consistent with the obtained for bedded sandstones supporting the idea that damage zones have an analogous effect - but vertically orientated - on bulk permeability (in low porosity rocks) as

  3. Near N-S paleo-extension in the western Deccan region, India: Does it link strike-slip tectonics with India-Seychelles rifting?

    Science.gov (United States)

    Misra, Achyuta Ayan; Bhattacharya, Gourab; Mukherjee, Soumyajit; Bose, Narayan

    2014-09-01

    This is the first detailed report and analyses of deformation from the W part of the Deccan large igneous province (DLIP), Maharashtra, India. This deformation, related to the India-Seychelles rifting during Late Cretaceous-Early Paleocene, was studied, and the paleostress tensors were deduced. Near N-S trending shear zones, lineaments, and faults were already reported without significant detail. An E-W extension was envisaged by the previous workers to explain the India-Seychelles rift at ~64 Ma. The direction of extension, however, does not match with their N-S brittle shear zones and also those faults (sub-vertical, ~NE-SW/~NW-SE, and few ~N-S) we report and emphasize in this work. Slickenside-bearing fault planes, brittle shear zones, and extension fractures in meso-scale enabled us to estimate the paleostress tensors (directions and relative magnitudes). The field study was complemented by remote sensing lineament analyses to map dykes and shear zones. Dykes emplaced along pre-existing ~N-S to ~NE-SW/~NW-SE shears/fractures. This information was used to derive regional paleostress trends. A ~NW-SE/NE-SW minimum compressive stress in the oldest Kalsubai Subgroup and a ~N-S direction for the younger Lonavala, Wai, and Salsette Subgroups were deciphered. Thus, a ~NW/NE to ~N-S extension is put forward that refutes the popular view of E-W India-Seychelles extension. Paleostress analyses indicate that this is an oblique rifted margin. Field criteria suggest only ~NE-SW and ~NW-SE, with some ~N-S strike-slip faults/brittle shear zones. We refer this deformation zone as the "Western Deccan Strike-slip Zone" (WDSZ). The observed deformation was matched with offshore tectonics deciphered mainly from faults interpreted on seismic profiles and from magnetic seafloor spreading anomalies. These geophysical findings too indicate oblique rifting in this part of the W Indian passive margin. We argue that the Seychelles microcontinent separated from India only after much of

  4. Tsunamis from strike-slip earthquakes in the Wharton Basin, northeast Indian Ocean: March 2016 Mw7.8 event and its relationship with the April 2012 Mw 8.6 event

    Science.gov (United States)

    Heidarzadeh, Mohammad; Harada, Tomoya; Satake, Kenji; Ishibe, Takeo; Takagawa, Tomohiro

    2017-12-01

    The Wharton Basin, off southwest Sumatra, ruptured to a large intraplate left-lateral strike-slip Mw 7.8 earthquake on 2016 March 2. The epicentre was located ∼800 km to the south of another similar-mechanism intraplate Mw 8.6 earthquake in the same basin on 2012 April 11. Small tsunamis from these strike-slip earthquakes were registered with maximum amplitudes of 0.5-1.5 cm on DARTs and 1-19 cm on tide gauges for the 2016 event, and the respective values of 0.5-6 and 6-40 cm for the 2012 event. By using both teleseismic body waves and tsunami observations of the 2016 event, we obtained optimum slip models with rupture velocity (Vr) in the range of 2.8-3.6 km s-1 belonging to both EW and NS faults. While the EW fault plane cannot be fully ruled out, we chose the best model as the NS fault plane with a Vr of 3.6 km s-1, a maximum slip of 7.7 m and source duration of 33 s. The tsunami energy period bands were 4-15 and 7-24 min for the 2016 and 2012 tsunamis, respectively, reflecting the difference in source sizes. Seismicity in the Wharton Basin is dominated by large strike-slip events including the 2012 (Mw 8.6 and 8.2) and 2016 (Mw 7.8) events, indicating that these events are possible tsunami sources in the Wharton Basin. Cumulative number and cumulative seismic-moment curves revealed that most earthquakes are of strike-slip mechanisms and the largest seismic-moment is provided by the strike-slip earthquakes in this basin.

  5. A Comparison of Geodetic and Geologic Rates Prior to Large Strike-Slip Earthquakes: A Diversity of Earthquake-Cycle Behaviors?

    Science.gov (United States)

    Dolan, James F.; Meade, Brendan J.

    2017-12-01

    Comparison of preevent geodetic and geologic rates in three large-magnitude (Mw = 7.6-7.9) strike-slip earthquakes reveals a wide range of behaviors. Specifically, geodetic rates of 26-28 mm/yr for the North Anatolian fault along the 1999 MW = 7.6 Izmit rupture are ˜40% faster than Holocene geologic rates. In contrast, geodetic rates of ˜6-8 mm/yr along the Denali fault prior to the 2002 MW = 7.9 Denali earthquake are only approximately half as fast as the latest Pleistocene-Holocene geologic rate of ˜12 mm/yr. In the third example where a sufficiently long pre-earthquake geodetic time series exists, the geodetic and geologic rates along the 2001 MW = 7.8 Kokoxili rupture on the Kunlun fault are approximately equal at ˜11 mm/yr. These results are not readily explicable with extant earthquake-cycle modeling, suggesting that they may instead be due to some combination of regional kinematic fault interactions, temporal variations in the strength of lithospheric-scale shear zones, and/or variations in local relative plate motion rate. Whatever the exact causes of these variable behaviors, these observations indicate that either the ratio of geodetic to geologic rates before an earthquake may not be diagnostic of the time to the next earthquake, as predicted by many rheologically based geodynamic models of earthquake-cycle behavior, or different behaviors characterize different fault systems in a manner that is not yet understood or predictable.

  6. Seismically-triggered soft-sediment deformation structures close to a major strike-slip fault system in the Eastern Alps (Hirlatz cave, Austria)

    Science.gov (United States)

    Salomon, Martina Lan; Grasemann, Bernhard; Plan, Lukas; Gier, Susanne; Schöpfer, Martin P. J.

    2018-05-01

    We investigate episodic soft-sediment deformation structures cross-cut by normal faults preserved in unlithified finely laminated calcite rich sediments in the Hirlatz cave in the Northern Calcareous Alps (Austria). These sediments comprise varve-like alternations of brighter carbonate/quartz rich layers, and darker clay mineral rich layers. The deformed sediments contain abundant millimeter to centimeter-scale soft-sediment structures (load casts, ball-and-pillow structures), sheet slumps (thrust faults and folds), erosive channels filled with slides and chaotic slumps. After deposition and soft-sediment deformation normal faults developed within the entire sedimentary succession, an event that probably correlates with an offset of c. 10 cm of the passage wall above the outcrop. Our major conclusions are: (i) The sediments have a glacial origin and were deposited in the Hirlatz cave under phreatic fluvio-lacustrine conditions. The deposition and the soft-sediment deformation occurred most likely during the last glaciation (i.e. around 25 ka ago); (ii) The liquefaction and formation of the soft-sediment structures in water-saturated stratified layers was triggered by episodic seismic events; (iii) The internally deformed sediments were later displaced by normal faults; (iv) A possible source for the seismic events is the active sinistral Salzach-Ennstal-Mariazeller-Puchberger (SEMP) strike-slip fault which is located about 10 km south of the outcrop and plays a major role in accommodating the extrusion of the Eastern Alps towards the Pannonian Basin. To our knowledge, the described structures are the first report of liquefaction and seismically induced soft-sediment deformations in Quaternary sediments in the Eastern Alps.

  7. 3D deformation in strike-slip systems: Analogue modelling and numerical restoration Deformación 3D en sistemas de rumbo: modelación analógica y restauración numérica

    Directory of Open Access Journals (Sweden)

    Daniel González

    2012-05-01

    Full Text Available Regional and local strike-slip systems in Chile are complex and pose interesting questions, such as the interaction between strike-slip and reverse faults, how they evolve, and the relationship between shortening, rotation and uplift. Within this context, we developed a new analytical method based on analogue and numerical modelling applied to 3D, pure and transtensional-transpressional strike-slip systems. Analogue modelling results indicate that in restraining stepovers of strike-slip fault systems, where antiformal pop-up structures are usually formed, pre-existent basement structures with a high angle to the main strike-slip fault will generate a higher rotation of blocks. However, when these structures are oriented at a high angle with respect to the main stress convergence vector, the rotation will be less and therefore a higher tendency to uplift will be produced. These results were applied to NW- and SE-striking basement faults oblique to N-S mega-thrust faults in central Chile (32°-35°S, for which we propose a simultaneous development based on the analogue model results. Moreover, we propose that strike-slip movement occurred on thrust faults in central Chile. Furthermore, we performed a numerical restoration of an analogue experiment which modeled a pure strike-slip system, and concluded that the restoration is very sensitive to shortening data as well as to rotational data. These results are extremely important for future numerical and regional analysis of strike-slip systems.Los sistemas de rumbo regionales y locales en Chile son complejos y plantean interesantes preguntas, tales como la interacción entre fallas de rumbo y fallas inversas, cómo evolucionan ellas, y la relación entre acortamiento, rotación y alzamiento. En este contexto, desarrollamos un nuevo método analítico basado en modelamiento analógico y numérico de sistemas de rumbo de cizalle puro y sistemas transpresionales-trantensionales en 3D. Los resultados del

  8. Structure of the la VELA Offshore Basin, Western Venezuela: AN Obliquely-Opening Rift Basin Within the South America-Caribbean Strike-Slip Plate Boundary

    Science.gov (United States)

    Blanco, J. M.; Mann, P.

    2015-12-01

    Bathymetric, gravity and magnetic maps show that the east-west trend of the Cretaceous Great Arc of the Caribbean in the Leeward Antilles islands is transected by an en echelon series of obliquely-sheared rift basins that show right-lateral offsets ranging from 20 to 40 km. The basins are 75-100 km in length and 20-30 km in width and are composed of sub-parallel, oblique slip normal faults that define deep, bathymetric channels that bound the larger islands of the Leeward Antilles including Aruba, Curacao and Bonaire. A single basin of similar orientation and structure, the Urumaco basin, is present to the southwest in the Gulf of Venezuela. We mapped structures and sedimentation in the La Vela rift basin using a 3D seismic data volume recorded down to 6 seconds TWT. The basin can be mapped from the Falcon coast where it is correlative with the right-lateral Adicora fault mapped onshore, and its submarine extension. To the southeast of the 3D survey area, previous workers have mapped a 70-km-wide zone of northeast-striking, oblique, right-lateral faults, some with apparent right-lateral offsets of the coastline. On seismic data, the faults vary in dip from 45 to 60 degrees and exhibit maximum vertical offsets of 600 m. The La Vela and other obliquely-opening rifts accommodate right-lateral shear with linkages to intervening, east-west-striking right-lateral faults like the Adicora. The zone of oblique rifts is restricted to the trend of the Great Arc of the Caribbean and may reflect the susceptiblity of this granitic basement to active shearing. The age of onset for the basins known from previous studies on the Leeward Antilles is early Miocene. As most of these faults occur offshore their potential to generate damaging earthquakes in the densely populated Leeward Antilles is not known.

  9. Hematite (U-Th)/He thermochronometry constrains intraplate strike-slip faulting on the Kuh-e-Faghan Fault, central Iran

    Science.gov (United States)

    Calzolari, Gabriele; Rossetti, Federico; Ault, Alexis K.; Lucci, Federico; Olivetti, Valerio; Nozaem, Reza

    2018-03-01

    The Kuh-e-Faghan strike-slip fault system (KFF), located to the northern edge of the Lut Block in central Iran, developed through a Neogene-Quaternary pulsed history of eastward fault propagation and fault-related exhumation. This system is a consequence of the residual stresses transmitted from the Arabia-Eurasia convergent plate boundary. Here we integrate structural and textural analysis with new and previously published apatite fission-track (AFT) and apatite (U-Th)/He (apatite He) results, chlorite thermomentry, and hematite (U-Th)/He data from hematite-coated brittle fault surfaces to constrain the timing of tectonic activity and refine patterns of late Miocene-Pliocene burial and exhumation associated with the propagation of the KFF. Twenty-nine hematite (U-Th)/He (hematite He) dates from three striated hematite coated slip surfaces from the KFF fault core and damage zone yield individual dates from 12-2 Ma. Petrographic analysis and chlorite thermometry of a polyphase, fossil fluid system in the KFF fault core document that fluid circulation and mineralization transitioned from a closed system characterized by pressure solution and calcite growth to an open system characterized by hot hydrothermal (T = 239 ± 10 °C) fluids and hematite formation. Hematite microtextures and grain size analysis reveal primary and secondary syntectonic hematite fabrics, no evidence of hematite comminution and similar hematite He closure temperatures ( 60-85 °C) in each sample. Integration of these results with thermal history modeling of AFT and apatite He data shows that KFF activity in the late Miocene is characterized by an early stage of fault nucleation, fluid circulation, hematite mineralization, and eastward propagation not associated with vertical movement that lasted from 12 to 7 Ma. Hematite He, AFT, and apatite He data track a second phase of fault system activity involving fault-related exhumation initiating at 7 Ma and continuing until present time. Our new data

  10. Middle Pleistocene infill of Hinkley Valley by Mojave River sediment and associated lake sediment: Depositional architecture and deformation by strike-slip faults

    Science.gov (United States)

    Miller, David; Haddon, Elizabeth; Langenheim, Victoria; Cyr, Andrew J.; Wan, Elmira; Walkup, Laura; Starratt, Scott W.

    2018-01-01

    avulsed through the valley, rather than continuing toward Lake Manix, during the late Pleistocene. Two dextral strike-slip fault zones, the Lockhart and the Mt. General, fold and displace the distinctive stratigraphic units, as well as surficial late Pleistocene and Holocene deposits. The sedimentary architecture and the two fault zones provide a framework for evaluating groundwater flow in Hinkley Valley.

  11. Constraints on the rheology of the lower crust in a strike-slip plate boundary: evidence from the San Quintín xenoliths, Baja California, Mexico

    Science.gov (United States)

    van der Werf, Thomas; Chatzaras, Vasileios; Marcel Kriegsman, Leo; Kronenberg, Andreas; Tikoff, Basil; Drury, Martyn R.

    2017-12-01

    The rheology of lower crust and its transient behavior in active strike-slip plate boundaries remain poorly understood. To address this issue, we analyzed a suite of granulite and lherzolite xenoliths from the upper Pleistocene-Holocene San Quintín volcanic field of northern Baja California, Mexico. The San Quintín volcanic field is located 20 km east of the Baja California shear zone, which accommodates the relative movement between the Pacific plate and Baja California microplate. The development of a strong foliation in both the mafic granulites and lherzolites, suggests that a lithospheric-scale shear zone exists beneath the San Quintín volcanic field. Combining microstructural observations, geothermometry, and phase equilibria modeling, we estimated that crystal-plastic deformation took place at temperatures of 750-890 °C and pressures of 400-560 MPa, corresponding to 15-22 km depth. A hot crustal geotherm of 40 ° C km-1 is required to explain the estimated deformation conditions. Infrared spectroscopy shows that plagioclase in the mafic granulites is relatively dry. Microstructures are interpreted to show that deformation in both the uppermost lower crust and upper mantle was accommodated by a combination of dislocation creep and grain-size-sensitive creep. Recrystallized grain size paleopiezometry yields low differential stresses of 12-33 and 17 MPa for plagioclase and olivine, respectively. The lower range of stresses (12-17 MPa) in the mafic granulite and lherzolite xenoliths is interpreted to be associated with transient deformation under decreasing stress conditions, following an event of stress increase. Using flow laws for dry plagioclase, we estimated a low viscosity of 1.1-1.3×1020 Pa ṡ s for the high temperature conditions (890 °C) in the lower crust. Significantly lower viscosities in the range of 1016-1019 Pa ṡ s, were estimated using flow laws for wet plagioclase. The shallow upper mantle has a low viscosity of 5.7×1019 Pa ṡ s

  12. Inferences about the local stress field from focal mechanisms: Applications to earthquakes in the southern Great Basin of Nevada

    International Nuclear Information System (INIS)

    Harmsen, S.C.; Rogers, A.M.

    1986-01-01

    Focal mechanisms determined from regional-network earthquake data or aftershock field investigation often contain members ranging from strike slip to normal slip in extensional tectonic environments or from strike slip to thrust slip in compressional environments. Although the coexistence of normal and strike-slip faulting has suggested to some investigators that the maximum and intermediate principal stresses are of approximately equal magnitude, several have asserted that the directions of principle stresses can or must interchange to accommodate both types of mechanisms (Zoback and Zoback 1980b; Vetter and Ryall, 1983). A Coulomb-Navier criterion of slip is invoked to demonstrate that both types of mechanisms, as well as oblique members having preferred nodal-plane dips intermediate between those of the strike-slip and normal mechanisms, may be observed in a region where the stress field, resolved into principal components, is axially symmetric. The proximate coexistence of earthquakes having diverse focal mechanisms could be interpreted as evidence for an approximately axially symmetric stress field in a region where optimally oriented planes of weakness are known to exist in the host rock. 10 refs., 6 figs

  13. Levels of conflict in reasoning modulate right lateral prefrontal cortex.

    Science.gov (United States)

    Stollstorff, Melanie; Vartanian, Oshin; Goel, Vinod

    2012-01-05

    Right lateral prefrontal cortex (rlPFC) has previously been implicated in logical reasoning under conditions of conflict. A functional magnetic resonance imaging (fMRI) study was conducted to explore its role in conflict more precisely. Specifically, we distinguished between belief-logic conflict and belief-content conflict, and examined the role of rlPFC under each condition. The results demonstrated that a specific region of rlPFC is consistently activated under both types of conflict. Moreover, the results of a parametric analysis demonstrated that the same region was modulated by the level of conflict contained in reasoning arguments. This supports the idea that this specific region is engaged to resolve conflict, including during deductive reasoning. This article is part of a Special Issue entitled "The Cognitive Neuroscience of Thought". Copyright © 2011 Elsevier B.V. All rights reserved.

  14. FMC: a one-liner Python program to manage, classify and plot focal mechanisms

    Science.gov (United States)

    Álvarez-Gómez, José A.

    2014-05-01

    is similar to the Johnston et al. (1994) classification; with 7 classes of earthquakes: 1) Normal; 2) Normal - Strike-slip; 3) Strike-slip - Normal; 4) Strike-slip; 5) Strike-slip - Reverse; 6) Reverse - strike-slip and 7) Reverse. FMC uses by default this classification in the resulting diagram, based on the Kaverina et al. (1996) projection, which improves the Frohlich and Apperson (1992) ternary diagram.

  15. Influencia de un bloque rígido en un sistema de fallas de rumbo: modelamiento análogo Influence of a rigid block in a strike-slip fault system: analogue modelling

    Directory of Open Access Journals (Sweden)

    Thierry Nalpas

    2011-01-01

    Full Text Available En este trabajo se presenta un estudio de modelamiento análogo sobre la naturaleza, geometría y cinemática de la deformación a lo largo de fallas de rumbo dada la presencia de un bloque rígido en su trayectoria de deformación. Los modelos análogos están apropiadamente escalados considerando las características reológicas de los materiales que se desean contrastar en la deformación. Dos grandes parámetros fueron probados: la configuración del bloque rígido, variando su forma y tamaño, y el monto del desplazamiento. Los resultados experimentales muestran el desarrollo de rotaciones, fallas y pliegues como producto de la presencia de un bloque rígido en la trayectoria de falla. Los diversos casos geométricos probados pueden ser empleados para su comparación con sistemas de fallas de rumbo en los cuales existen diferencias litológicas de comportamiento reológico diferencial, como por ejemplo el caso del 'Núcleo rígido de Limón Verde' al sur de Chuquicamata, ubicado en la trayectoria del sistema de fallas de Domeyko.This work addresses the kinematic effects of a rigid block in strike-slip systems by using analogue models. The experiments (size, behaviour of materials were scaled down in order to represent deformation of the tested rheologic contrast conditions in deformation. Two main parameters were tested: the configuration of the rigid block, changing its form and size, and the amount of displacement. The experiments evidenced the development of rotations, faults and folds along the fault trajectory, as resulting from the presence of the rigid block during the deformation. Testing of diverse geometric situations may be used for comparison to strike-slip fault systems in which different lithologies and rheologic behaviour exist, for example, presence of the 'Limón Verde rigid core' along the Domeyko fault system, just south of Chuquicamata.

  16. A calcified epidermoid cyst within right lateral ventricle: A report of a rare case

    OpenAIRE

    Ranjan Kumar Sahoo; Debahuti Mohapatra; Pradipta Tripathy

    2016-01-01

    A young patient reported to neurosurgery outdoor department with symptoms of increased intracranial pressure. Noncontrast computed tomography examination showed a single calcified mass within right lateral ventricle with mild hydrocephalus. Contrast-enhanced magnetic resonance imaging revealed nonenhancing single mass within right lateral ventricle with mild hydrocephalus. Intraventricular calcified choroid papilloma/calcified epidermoid were radiological differentials. The mass was excised, ...

  17. A calcified epidermoid cyst within right lateral ventricle: A report of a rare case

    Directory of Open Access Journals (Sweden)

    Ranjan Kumar Sahoo

    2016-01-01

    Full Text Available A young patient reported to neurosurgery outdoor department with symptoms of increased intracranial pressure. Noncontrast computed tomography examination showed a single calcified mass within right lateral ventricle with mild hydrocephalus. Contrast-enhanced magnetic resonance imaging revealed nonenhancing single mass within right lateral ventricle with mild hydrocephalus. Intraventricular calcified choroid papilloma/calcified epidermoid were radiological differentials. The mass was excised, removed from the lateral ventricles and found to be calcified epidermoid on gross and microscopic examination, which is rare.

  18. Seismic attribute detection of faults and fluid pathways within an active strike-slip shear zone: New insights from high-resolution 3D P-Cable™ seismic data along the Hosgri Fault, offshore California

    Science.gov (United States)

    Kluesner, Jared W.; Brothers, Daniel

    2016-01-01

    Poststack data conditioning and neural-network seismic attribute workflows are used to detect and visualize faulting and fluid migration pathways within a 13.7 km2 13.7 km2 3D P-Cable™ seismic volume located along the Hosgri Fault Zone offshore central California. The high-resolution 3D volume used in this study was collected in 2012 as part of Pacific Gas and Electric’s Central California Seismic Imaging Project. Three-dimensional seismic reflection data were acquired using a triple-plate boomer source (1.75 kJ) and a short-offset, 14-streamer, P-Cable system. The high-resolution seismic data were processed into a prestack time-migrated 3D volume and publically released in 2014. Postprocessing, we employed dip-steering (dip and azimuth) and structural filtering to enhance laterally continuous events and remove random noise and acquisition artifacts. In addition, the structural filtering was used to enhance laterally continuous edges, such as faults. Following data conditioning, neural-network based meta-attribute workflows were used to detect and visualize faults and probable fluid-migration pathways within the 3D seismic volume. The workflow used in this study clearly illustrates the utility of advanced attribute analysis applied to high-resolution 3D P-Cable data. For example, results from the fault attribute workflow reveal a network of splayed and convergent fault strands within an approximately 1.3 km wide shear zone that is characterized by distinctive sections of transpressional and transtensional dominance. Neural-network chimney attribute calculations indicate that fluids are concentrated along discrete faults in the transtensional zones, but appear to be more broadly distributed amongst fault bounded anticlines and structurally controlled traps in the transpressional zones. These results provide high-resolution, 3D constraints on the relationships between strike-slip fault mechanics, substrate deformation, and fluid migration along an active

  19. Constraints on the rheology of the lower crust in a strike-slip plate boundary: evidence from the San Quintín xenoliths, Baja California, Mexico

    Directory of Open Access Journals (Sweden)

    T. van der Werf

    2017-12-01

    Full Text Available The rheology of lower crust and its transient behavior in active strike-slip plate boundaries remain poorly understood. To address this issue, we analyzed a suite of granulite and lherzolite xenoliths from the upper Pleistocene–Holocene San Quintín volcanic field of northern Baja California, Mexico. The San Quintín volcanic field is located 20 km east of the Baja California shear zone, which accommodates the relative movement between the Pacific plate and Baja California microplate. The development of a strong foliation in both the mafic granulites and lherzolites, suggests that a lithospheric-scale shear zone exists beneath the San Quintín volcanic field. Combining microstructural observations, geothermometry, and phase equilibria modeling, we estimated that crystal-plastic deformation took place at temperatures of 750–890 °C and pressures of 400–560 MPa, corresponding to 15–22 km depth. A hot crustal geotherm of 40 ° C km−1 is required to explain the estimated deformation conditions. Infrared spectroscopy shows that plagioclase in the mafic granulites is relatively dry. Microstructures are interpreted to show that deformation in both the uppermost lower crust and upper mantle was accommodated by a combination of dislocation creep and grain-size-sensitive creep. Recrystallized grain size paleopiezometry yields low differential stresses of 12–33 and 17 MPa for plagioclase and olivine, respectively. The lower range of stresses (12–17 MPa in the mafic granulite and lherzolite xenoliths is interpreted to be associated with transient deformation under decreasing stress conditions, following an event of stress increase. Using flow laws for dry plagioclase, we estimated a low viscosity of 1.1–1.3×1020 Pa ⋅ s for the high temperature conditions (890 °C in the lower crust. Significantly lower viscosities in the range of 1016–1019 Pa ⋅ s, were estimated using flow laws for wet plagioclase. The

  20. Transcurrencia a lo largo de la Falla Sierra de Varas (Sistema de fallas de la Cordillera de Domeyko, norte de Chile Strike-slip along the Sierra de Varas Fault (Cordillera de Domeyko Fault-System, northern Chile

    Directory of Open Access Journals (Sweden)

    Hans Niemeyer

    2009-01-01

    Aguada del Hornito-Aguada del Cerro Alto de Varas segment. Upper Paleozoic granitoids of the same composition, internal structure and age were cut and displaced by the fault. A sinistral horizontal separation of 15.6±1 kmwitha vertical componentof 4.9±0.1 km, suggests a sinistral-reverse net displacement of 16.4±1 km. Thisis consistent with the local stratigraphic section that was eroded from the eastern block. A kinematic and dynamic analysis of mesofaults spatially related to the SVF displacements was conducted to identify the different fault populations and to obtain the stress tensor. Two structural systems were identified: an early reverse-strike-slip system and a late dextral superposed system. The first one ocurred during late middle Eocene, and the second is post-Miocene with an horizontal displacement of 0.6 km. The presence of coeval strike-slip displacements along the Sierra de Varas Fault and reverse displacements in a 'reverse flower' in the studied segment show that the structural evolution of the Sierra de Varas was dominated by a bulk transpression during the late middle Eocene. The left-lateral displacement here demonstrated for the Sierra de Varas Fault and its inflection to the SE, south of the Aguada del Cerro Alto de Varas are compatible with the westward vergence of the folds and reverse faults in the El Profeta fault-and-thrust belt, which should be also the result of the transpression.

  1. New method for evaluation of perigastric invasion of gastric cancer by right lateral position CT

    International Nuclear Information System (INIS)

    Shirakawa, T.; Fukuda, K.; Tada, S.

    1996-01-01

    The purpose of this study was to evaluate usefulness of right lateral position CT in determining invasion of gastric cancer into adjacent organs. We assessed whether position shift, a change in the relative location of a gastric tumor and adjacent organs between the supine position and right lateral position CT, was a useful sign for absence of invasion into perigastric organs. In 37 patients with advanced gastric cancer with doubtful invasion into adjacent organs by conventional CT after 500 ml water oral intake, additive right lateral CT was performed. Of 24 cases of lesions in the gastric body, 16 had a position shift and no invasion into adjacent organs at surgery (T3), and 8 had no position shift and invasion (T4). The accuracy was 100%. Six gastric cardial and 7 pyloric tumors showed no position shift, and 3 cardial and 2 pyloric tumors were proved to be nonivasive (T3). The accuracy of cardial and pyloric tumor was 50 and 71%. We concluded that position shift may be useful in the diagnosis of invasion of adjacent organs by gastric cancer, limited to in cases with gastric body cancer. (orig.)

  2. Focal mechanism of the seismic series prior to the 2011 El Hierro eruption

    Science.gov (United States)

    del Fresno, C.; Buforn, E.; Cesca, S.; Domínguez Cerdeña, I.

    2015-12-01

    The onset of the submarine eruption of El Hierro (10-Oct-2011) was preceded by three months of low-magnitude seismicity (Mw3.5). Amplitude spectra was fitted at local distances (<20km). Reliability and stability of the results were evaluated with synthetic data. Results show a change in the focal mechanism pattern within the first days of October, varying from complex sources of higher non-double-couple components before that date to a simpler strike-slip mechanism with horizontal tension axes on E-W direction the week prior to the eruption onset. A detailed study was carried out for the 8 October 2011 earthquake (Mw=4.0). Focal mechanism was retrieved using a MT inversion at regional and local distances. Results indicate an important component of strike-slip fault and null isotropic component. The stress pattern obtained corresponds to horizontal compression in a NNW-SSE direction, parallel to the southern ridge of the island, and a quasi-horizontal extension in an EW direction. Finally, a simple source time function of 0.3s has been estimated for this shock using the Empirical Green function methodology.

  3. Stress regimes in the northwest of Iran from stress inversion of earthquake focal mechanisms

    Science.gov (United States)

    Afra, Mahsa; Moradi, Ali; Pakzad, Mehrdad

    2017-11-01

    Northwestern Iran is one of the seismically active regions with a high seismic risk in the world. This area is a part of the complex tectonic system due to the interaction between Arabia, Anatolia and Eurasia. The purpose of this study is to deduce the stress regimes in the northwestern Iran and surrounding regions from stress inversion of earthquake focal mechanisms. We compile 92 focal mechanisms data from the Global CMT catalogue and other sources and also determine the focal mechanisms of 14 earthquakes applying the moment tensor inversion. We divide the studied region into 9 zones using similarity of the horizontal GPS velocities and existing focal mechanisms. We implement two stress inversion methods, Multiple Inverse Method and Iterative Joint Inversion Method, which provide comparable results in terms of orientations of maximum horizontal stress axes SHmax. The similar results of the two methods should make us more confident about the interpretations. We consider zones of exclusion surrounding all the earthquakes according to independent focal mechanisms hypothesis. The hypothesis says that the inversion should involve events that are far enough from each other in order that any previous event doesn't affect the stress field near the earthquake under consideration. Accordingly we deal with the matter by considering zones of exclusion around all the events. The result of exclusion is only significant for eastern Anatolia. The stress regime in this region changes from oblique to strike slip faulting because of the exclusion. In eastern Anatolia, the direction of maximum horizontal stress is nearly north-south. The direction alters to east-west in Talesh region. Errors of σ1 are lower in all zones comparing with errors of σ2 and σ3 and there is a trade-off between data resolution and covariance of the model. The results substantiate the strike-slip and thrust faulting stress regimes in the northwest of Iran.

  4. Focal myositis

    International Nuclear Information System (INIS)

    Kransdorf, M.J.; Temple, H.T.; Sweet, D.E.

    1998-01-01

    Focal myositis is a pseudotumor of soft tissue that typically occurs in the deep soft tissue of the extremities, and is a relatively rare lesion. There is a wide clinical spectrum, with approximately one-third of patients with focal myositis subsequently developing polymyositis, and clinical symptoms of generalized weakness, fever, myalgia, and weight loss, with elevation of creatine phosphokinase. We report the case of a patient with focal myositis who subsequently developed myositis ossificans-like features. (orig.)

  5. Earthquake focal mechanism forecasting in Italy for PSHA purposes

    Science.gov (United States)

    Roselli, Pamela; Marzocchi, Warner; Mariucci, Maria Teresa; Montone, Paola

    2018-01-01

    In this paper, we put forward a procedure that aims to forecast focal mechanism of future earthquakes. One of the primary uses of such forecasts is in probabilistic seismic hazard analysis (PSHA); in fact, aiming at reducing the epistemic uncertainty, most of the newer ground motion prediction equations consider, besides the seismicity rates, the forecast of the focal mechanism of the next large earthquakes as input data. The data set used to this purpose is relative to focal mechanisms taken from the latest stress map release for Italy containing 392 well-constrained solutions of events, from 1908 to 2015, with Mw ≥ 4 and depths from 0 down to 40 km. The data set considers polarity focal mechanism solutions until to 1975 (23 events), whereas for 1976-2015, it takes into account only the Centroid Moment Tensor (CMT)-like earthquake focal solutions for data homogeneity. The forecasting model is rooted in the Total Weighted Moment Tensor concept that weighs information of past focal mechanisms evenly distributed in space, according to their distance from the spatial cells and magnitude. Specifically, for each cell of a regular 0.1° × 0.1° spatial grid, the model estimates the probability to observe a normal, reverse, or strike-slip fault plane solution for the next large earthquakes, the expected moment tensor and the related maximum horizontal stress orientation. These results will be available for the new PSHA model for Italy under development. Finally, to evaluate the reliability of the forecasts, we test them with an independent data set that consists of some of the strongest earthquakes with Mw ≥ 3.9 occurred during 2016 in different Italian tectonic provinces.

  6. Focal myositis

    International Nuclear Information System (INIS)

    Galloway, H.R.; Dahlstrom, J.E.; Bennett, G.M.

    2001-01-01

    Focal myositis is a rare, benign focal inflammation of muscle. The lesion often presents as a mass that may be mistaken for a soft tissue sarcoma. This report describes the MRI and histopathological features of a case and illustrates how the diagnosis may be suspected on the basis of the MR findings. Copyright (2001) Blackwell Science Pty Ltd

  7. Focal myositis

    Energy Technology Data Exchange (ETDEWEB)

    Kransdorf, M.J. [Saint Mary`s Hospital, Richmond, VA (United States). Dept. of Radiol.]|[Department of Radiologic Pathology, Armed Forces Institute of Pathology, Washington, DC (United States); Temple, H.T. [Department of Orthopedic Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia (United States)]|[Department of Orthopedic Pathology, Armed Forces Institute of Pathology, Washington, DC (United States); Sweet, D.E. [Department of Orthopedic Pathology, Armed Forces Institute of Pathology, Washington, DC (United States)

    1998-05-01

    Focal myositis is a pseudotumor of soft tissue that typically occurs in the deep soft tissue of the extremities, and is a relatively rare lesion. There is a wide clinical spectrum, with approximately one-third of patients with focal myositis subsequently developing polymyositis, and clinical symptoms of generalized weakness, fever, myalgia, and weight loss, with elevation of creatine phosphokinase. We report the case of a patient with focal myositis who subsequently developed myositis ossificans-like features. (orig.) With 3 figs., 25 refs.

  8. Earthquake focal mechanisms and stress orientations in the eastern Swiss Alps

    International Nuclear Information System (INIS)

    Marschall, I.; Deichmann, N.; Marone, F.

    2013-01-01

    This study presents an updated set of earthquake focal mechanisms in the Helvetic and Penninic/Austroalpine domains of the eastern Swiss Alps. In eight cases, based on high-precision relative hypocentre locations of events within individual earthquake sequences, it was possible to identify the active fault plane. Whereas the focal mechanisms in the Helvetic domain are mostly strike-slip, the Penninic/Austroalpine domain is dominated by normal-faulting mechanisms. Given this systematic difference in faulting style, an inversion for the stress field was performed separately for the two regions. The stress field in the Penninic/Austroalpine domain is characterized by extension oriented obliquely to the E-W strike of the orogen. Hence, the Penninic nappes, which were emplaced as large-scale compressional structures during the Alpine orogenesis, are now deforming in an extensional mode. This contrasts with the more compressional strike-slip regime in the Helvetic domain towards the northern Alpine front. Relative to the regional stress field seen in the northern Alpine foreland with a NNW-SSE compression and an ENE-WSW extension, the orientation of the least compressive stress in the Penninic/Austroalpine domain is rotated counter-clockwise by about 40 °C. Following earlier studies, the observed rotation of the orientation of the least compressive stress in the Penninic/Austroalpine region can be explained as the superposition of the regional stress field of the northern foreland and a uniaxial extensional stress perpendicular to the local trend of the Alpine mountain belt. (authors)

  9. An effective and safe gastric endoscopic submucosal dissection in the right lateral position using an inverted overtube

    OpenAIRE

    Mori, Hirohito; Rafiq, Kazi; Kobara, Hideki; Nishiyama, Noriko; Fujihara, Shintaro; Yachida, Tatsuo; Ayagi, Maki; Tani, Joji; Miyoshi, Hisaaki; Masaki, Tsutomu

    2014-01-01

    Previously, we reported the efficacy of a newly developed inverted overtube in shortening the hemostatic time and obtaining a clear endoscopic view in emergency endoscopic hemostasis. This device also helped us to perform gastric endoscopic submucosal dissection (ESD) more safely by changing the direction of gravity in the right lateral position. To perform a safe ESD, it is important to make an appropriate angle and distance between the electric knife and the gastric mucosa. In this position...

  10. Modulating phonemic fluency performance in healthy subjects with transcranial magnetic stimulation over the left or right lateral frontal cortex.

    Science.gov (United States)

    Smirni, Daniela; Turriziani, Patrizia; Mangano, Giuseppa Renata; Bracco, Martina; Oliveri, Massimiliano; Cipolotti, Lisa

    2017-07-28

    A growing body of evidence have suggested that non-invasive brain stimulation techniques, such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), can improve the performance of aphasic patients in language tasks. For example, application of inhibitory rTMS or tDCs over the right frontal lobe of dysphasic patients resulted in improved naming abilities. Several studies have also reported that in healthy controls (HC) tDCS application over the left prefrontal cortex (PFC) improve performance in naming and semantic fluency tasks. The aim of this study was to investigate in HC, for the first time, the effects of inhibitory repetitive TMS (rTMS) over left and right lateral frontal cortex (BA 47) on two phonemic fluency tasks (FAS or FPL). 44 right-handed HCs were administered rTMS or sham over the left or right lateral frontal cortex in two separate testing sessions, with a 24h interval, followed by the two phonemic fluency tasks. To account for possible practice effects, an additional 22 HCs were tested on only the phonemic fluency task across two sessions with no stimulation. We found that rTMS-inhibition over the left lateral frontal cortex significantly worsened phonemic fluency performance when compared to sham. In contrast, rTMS-inhibition over the right lateral frontal cortex significantly improved phonemic fluency performance when compared to sham. These results were not accounted for practice effects. We speculated that rTMS over the right lateral frontal cortex may induce plastic neural changes to the left lateral frontal cortex by suppressing interhemispheric inhibitory interactions. This resulted in an increased excitability (disinhibition) of the contralateral unstimulated left lateral frontal cortex, consequently enhancing phonemic fluency performance. Conversely, application of rTMS over the left lateral frontal cortex may induce a temporary, virtual lesion, with effects similar to those reported in left frontal

  11. Investigation of left and right lateral fluid percussion injury in C57BL6/J mice: In vivo functional consequences.

    Science.gov (United States)

    Schurman, Lesley D; Smith, Terry L; Morales, Anthony J; Lee, Nancy N; Reeves, Thomas M; Phillips, Linda L; Lichtman, Aron H

    2017-07-13

    Although rodent models of traumatic brain injury (TBI) reliably produce cognitive and motor disturbances, behavioral characterization resulting from left and right hemisphere injuries remains unexplored. Here we examined the functional consequences of targeting the left versus right parietal cortex in lateral fluid percussion injury, on Morris water maze (MWM) spatial memory tasks (fixed platform and reversal) and neurological motor deficits (neurological severity score and rotarod). In the MWM fixed platform task, right lateral injury produced a small delay in acquisition rate compared to left. However, injury to either hemisphere resulted in probe trial deficits. In the MWM reversal task, left-right performance deficits were not evident, though left lateral injury produced mild acquisition and probe trial deficits compared to sham controls. Additionally, left and right injury produced similar neurological motor task deficits, impaired righting times, and lesion volumes. Injury to either hemisphere also produced robust ipsilateral, and modest contralateral, morphological changes in reactive microglia and astrocytes. In conclusion, left and right lateral TBI impaired MWM performance, with mild fixed platform acquisition rate differences, despite similar motor deficits, histological damage, and glial cell reactivity. Thus, while both left and right lateral TBI produce cognitive deficits, laterality in mouse MWM learning and memory merits consideration in the investigation of TBI-induced cognitive consequences. Copyright © 2017. Published by Elsevier B.V.

  12. Strike slip faulting inferred from offsetting of drainages: Lower ...

    Indian Academy of Sciences (India)

    Two levels of fluvial terraces have developed along the ... (a) Two levels of alluvial terraces abutting against the .... source mechanics; (eds) Das J, Boatwright J, Scholz C H, ... tectonics and alluvial rivers; Cambridge University Press. NY, 276 ...

  13. Tectonic stress orientations and magnitudes, and friction of faults, deduced from earthquake focal mechanism inversions over the Korean Peninsula

    Science.gov (United States)

    Soh, Inho; Chang, Chandong; Lee, Junhyung; Hong, Tae-Kyung; Park, Eui-Seob

    2018-05-01

    We characterize the present-day stress state in and around the Korean Peninsula using formal inversions of earthquake focal mechanisms. Two different methods are used to select preferred fault planes in the double-couple focal mechanism solutions: one that minimizes average misfit angle and the other choosing faults with higher instability. We invert selected sets of fault planes for estimating the principal stresses at regularly spaced grid points, using a circular-area data-binning method, where the bin radius is optimized to yield the best possible stress inversion results based on the World Stress Map quality ranking scheme. The inversions using the two methods yield well constrained and fairly comparable results, which indicate that the prevailing stress regime is strike-slip, and the maximum horizontal principal stress (SHmax) is oriented ENE-WSW throughout the study region. Although the orientation of the stresses is consistent across the peninsula, the relative stress magnitude parameter (R-value) varies significantly, from 0.22 in the northwest to 0.89 in the southeast. Based on our knowledge of the R-values and stress regime, and using a value for vertical stress (Sv) estimated from the overburden weight of rock, together with a value for the maximum differential stress (based on the Coulomb friction of faults optimally oriented for slip), we estimate the magnitudes of the two horizontal principal stresses. The horizontal stress magnitudes increase from west to east such that SHmax/Sv ratio rises from 1.5 to 2.4, and the Shmin/Sv ratio from 0.6 to 0.8. The variation in the magnitudes of the tectonic stresses appears to be related to differences in the rigidity of crustal rocks. Using the complete stress tensors, including both orientations and magnitudes, we assess the possible ranges of frictional coefficients for different types of faults. We show that normal and reverse faults have lower frictional coefficients than strike-slip faults, suggesting that

  14. Significado tectónico y migración de fluidos hidrotermales en una red de fallas y vetas de un Dúplex de rumbo: un ejemplo del Sistema de Falla de Atacama Tectonic significance and hydrothermal fluid migration within a strike-slip duplex fault-vein network: an example from the Atacama Fault System

    Directory of Open Access Journals (Sweden)

    Viviana Olivares

    2010-07-01

    Full Text Available El Dúplex Caleta Coloso es una estructura de rumbo desarrollada durante la deformación frágil del Sistema de Falla de Atacama (SFA en el Cretácico Temprano. En su interior hay un sistema de vetas hidrotermales que documentan la naturaleza de la relación entre el transporte de fluidos y el desarrollo del dúplex. El sistema de vetas de orientación dominante NW se localiza en la roca de caja, adyacentes a las zonas de falla. Según su mineralogía dominante hay vetas de clorita, epidota-cuarzo y calcita-limonita, y según las relaciones de corte o su estructura interna, se definieron vetas tempranas (clorita, intermedias (epidota-cuarzo y tardías (calcita-limonitas. Algunas vetas muestran cristales perpendiculares u oblicuos a sus paredes (vetas de extensión y de extensión oblicua o fibras minerales orientadas paralelas a las estrías de las fallas (vetas-fallas. Estas últimas tienen indicadores cinemáticos compatibles con las fallas, evidenciando que fueron sincinemáticas con el desarrollo del dúplex. Según su microestructura, ellas se habrían formado en fracturas abiertas llenas de fluidos, bajo condiciones de presión inferior a la hidrostática, lo cual indicaría que la precipitación mineral ocurrió por caídas abruptas de la presión en una corteza somera (The Caleta Coloso Duplex is a brittle strike-slip structure developed along the Atacama Fault System during the Early Cretaceous. A hydrothermal vein system existing within the duplex documents the nature of the link between fluid transport and progressive structural development. The dominantly NW-striking vein system occurs near or at the damage zone of the duplex fault zones. Veins can be classified according to their composition and crosscutting relationships into early chlorite veins, intermediate epidotic-quartz veins and late calcite-limonite veins. Some of them exhibit minerals with their long axes oriented orthogonally or obliquely with respect to the vein walls

  15. An effective and safe gastric endoscopic submucosal dissection in the right lateral position using an inverted overtube.

    Science.gov (United States)

    Mori, Hirohito; Rafiq, Kazi; Kobara, Hideki; Nishiyama, Noriko; Fujihara, Shintaro; Yachida, Tatsuo; Ayagi, Maki; Tani, Joji; Miyoshi, Hisaaki; Masaki, Tsutomu

    2014-02-14

    Previously, we reported the efficacy of a newly developed inverted overtube in shortening the hemostatic time and obtaining a clear endoscopic view in emergency endoscopic hemostasis. This device also helped us to perform gastric endoscopic submucosal dissection (ESD) more safely by changing the direction of gravity in the right lateral position. To perform a safe ESD, it is important to make an appropriate angle and distance between the electric knife and the gastric mucosa. In this position, the distance to gastric mucosa is reduced, and the angle of the electric knife changes from vertical to somewhat oblique, facilitating safer cutting.

  16. Right away: A late, right-lateralized category effect complements an early, left-lateralized category effect in visual search.

    Science.gov (United States)

    Constable, Merryn D; Becker, Stefanie I

    2017-10-01

    According to the Sapir-Whorf hypothesis, learned semantic categories can influence early perceptual processes. A central finding in support of this view is the lateralized category effect-namely, the finding that categorically different colors (e.g., blue and green hues) can be discriminated faster than colors within the same color category (e.g., different hues of green), especially when they are presented in the right visual field. Because the right visual field projects to the left hemisphere, this finding has been popularly couched in terms of the left-lateralization of language. However, other studies have reported bilateral category effects, which has led some researchers to question the linguistic origins of the effect. Here we examined the time course of lateralized and bilateral category effects in the classical visual search paradigm by means of eyetracking and RT distribution analyses. Our results show a bilateral category effect in the manual responses, which is combined of an early, left-lateralized category effect and a later, right-lateralized category effect. The newly discovered late, right-lateralized category effect occurred only when observers had difficulty locating the target, indicating a specialization of the right hemisphere to find categorically different targets after an initial error. The finding that early and late stages of visual search show different lateralized category effects can explain a wide range of previously discrepant findings.

  17. Recent state of stress change in the Walker Lane zone, western Basin and Range province, United States

    Science.gov (United States)

    Bellier, Olivier; Zoback, Mary Lou

    1995-06-01

    the youngest striae observed on faults in Plio-Quaternary deposits. Geologic control on the timing of the change is poor; it is impossible to determine if there has been a single recent absolute change or if there is, rather, an alternating or cyclical variation in stress magnitudes. Our slip data, in particular, the cross-cutting normal and strike-slip striae on the same fault plane, are inconsistent with postulated simple strain partitioning of deformation within a single regional stress field suggested for the WLZ by Wesnousky and Jones [1994]. The location of the WLZ between the deep-seated regional extension of the Basin and Range and the right-lateral strike-slip regional tectonics of the San Andreas fault zone is probably responsible for the complex interaction of tectonic regimes in this transition zone. In early to mid-Tertiary time the WLZ appears to have had a similarly complex deformational history, in this case as a back arc or intra-arc region, accommodating at least part of the right-lateral component of oblique convergence as well as a component of extension.

  18. Tectonics earthquake distribution pattern analysis based focal mechanisms (Case study Sulawesi Island, 1993–2012)

    International Nuclear Information System (INIS)

    Ismullah M, Muh. Fawzy; Lantu,; Aswad, Sabrianto; Massinai, Muh. Altin

    2015-01-01

    Indonesia is the meeting zone between three world main plates: Eurasian Plate, Pacific Plate, and Indo – Australia Plate. Therefore, Indonesia has a high seismicity degree. Sulawesi is one of whose high seismicity level. The earthquake centre lies in fault zone so the earthquake data gives tectonic visualization in a certain place. This research purpose is to identify Sulawesi tectonic model by using earthquake data from 1993 to 2012. Data used in this research is the earthquake data which consist of: the origin time, the epicenter coordinate, the depth, the magnitude and the fault parameter (strike, dip and slip). The result of research shows that there are a lot of active structures as a reason of the earthquake in Sulawesi. The active structures are Walannae Fault, Lawanopo Fault, Matano Fault, Palu – Koro Fault, Batui Fault and Moluccas Sea Double Subduction. The focal mechanism also shows that Walannae Fault, Batui Fault and Moluccas Sea Double Subduction are kind of reverse fault. While Lawanopo Fault, Matano Fault and Palu – Koro Fault are kind of strike slip fault

  19. Tectonics earthquake distribution pattern analysis based focal mechanisms (Case study Sulawesi Island, 1993–2012)

    Energy Technology Data Exchange (ETDEWEB)

    Ismullah M, Muh. Fawzy, E-mail: mallaniung@gmail.com [Master Program Geophysical Engineering, Faculty of Mining and Petroleum Engineering (FTTM), Bandung Institute of Technology (ITB), Jl. Ganesha no. 10, Bandung, 40116, Jawa Barat (Indonesia); Lantu,; Aswad, Sabrianto; Massinai, Muh. Altin [Geophysics Program Study, Faculty of Mathematics and Natural Sciences, Hasanuddin University (UNHAS), Jl. PerintisKemerdekaan Km. 10, Makassar, 90245, Sulawesi Selatan (Indonesia)

    2015-04-24

    Indonesia is the meeting zone between three world main plates: Eurasian Plate, Pacific Plate, and Indo – Australia Plate. Therefore, Indonesia has a high seismicity degree. Sulawesi is one of whose high seismicity level. The earthquake centre lies in fault zone so the earthquake data gives tectonic visualization in a certain place. This research purpose is to identify Sulawesi tectonic model by using earthquake data from 1993 to 2012. Data used in this research is the earthquake data which consist of: the origin time, the epicenter coordinate, the depth, the magnitude and the fault parameter (strike, dip and slip). The result of research shows that there are a lot of active structures as a reason of the earthquake in Sulawesi. The active structures are Walannae Fault, Lawanopo Fault, Matano Fault, Palu – Koro Fault, Batui Fault and Moluccas Sea Double Subduction. The focal mechanism also shows that Walannae Fault, Batui Fault and Moluccas Sea Double Subduction are kind of reverse fault. While Lawanopo Fault, Matano Fault and Palu – Koro Fault are kind of strike slip fault.

  20. Preliminary results of very fast computation of Moment Magnitude and focal mechanism in the context of tsunami warning

    Science.gov (United States)

    Schindelé, François; Roch, Julien; Rivera, Luis

    2015-04-01

    Various methodologies were recently developed to compute the moment magnitude and the focal mechanism, thanks to the real time access to numerous broad-band seismic data. Several methods were implemented at the CENALT, in particular the W-Phase method developed by H. Kanamori and L. Rivera. For earthquakes of magnitudes in the range 6.5-9.0, this method provides accurate results in less than 40 minutes. The context of the tsunami warning in Mediterranean, a small basin impacted in less than one hour, and with small sources but some with high tsunami potential (Boumerdes 2003), a comprehensive tsunami warning system in that region should include very fast computation of the seismic parameters. The results of the values of Mw, the focal depth and the type of fault (reverse, normal, strike-slip) are the most relevant parameters expected for the tsunami warning. Preliminary results will be presented using data in the North-eastern and Mediterranean region for the recent period 2010-2014. This work is funded by project ASTARTE - - Assessment, Strategy And Risk Reduction for Tsunamis in Europe - FP7-ENV2013 6.4-3, Grant 603839

  1. The value of right lateral decubitus position to decrease artificial defect of cardiac anterior wall in 99Tcm-MIBI SPECT myocardial perfusion imaging for women

    International Nuclear Information System (INIS)

    Huang Kemin; Feng Yanlin; Wen Guanghua; Liang Weitang; Yu Fengwen; Liu Dejun

    2013-01-01

    Objective: To explore the value of right lateral decubitus position MPI for differentiating myocardial perfusion defect from cardiac anterior wall attenuation artificial defect, caused by breast of woman. Methods: Forty-nine patients(average age (61.5±8.4) years) who had low likelihood of coronary artery disease and had perfusion defect in the anterior wall after exercise stress 99 Tc m -MIBI MPI were included. All underwent supine and right lateral decubitus position during resting SPECT images. The myocardial perfusion SPECT images at left ventricle were reconstructed and were measured by Bull's-eye, based on the counts. Results from both supine position imaging and right lateral decubitus position imaging were compared. Paired t test was used to statistically analyse the data by SPSS 13.0. Results: Compared with supine position, the counts of the anterior, inferior, apex and lateral wall in right lateral decubitus position were significantly higher: (71.30±3.53)% vs (66.50±3.85)%, (70.06±4.45)% vs (65.44±4.16)%, (77.90±3.00)% vs (75.81±4.08)%,(79.30±2.26)% vs (72.60±3.87)% (t=6.731, 5.286, 3.555, 10.885, all P<0.01). The counts of septal wall were significantly lower ((66.60±3.98)% vs (70.06±4.51)%, t=-4.625, P<0.01) in right lateral decubitus position than that in supine position. Among the different regions of anterior wall, the counts of the anterior-middle ((76.40 ± 3.80)% vs (68.60 ± 4.76)%) and anterior-apex region ((77.10±3.24)% vs (69.00±3.54)%) were significantly higher (t=9.916, 8.870, both P<0.01) in right lateral decubitus position than those in supine position, but there was insignificance ((56.94±6.06)% vs (58.50±4.98)%, t=-1.493, P>0.05) at anterior-basal region. The artificial defect of different degrees in anterior wall was observed in all patients in supine position, 23 cases (46.9%, 23/49) showed artificial defect in the anterior-middle region and 16 cases (32.7%, 16/49) in the anterior-apex region. All artificial defect

  2. Fluid Collection in the Right Lateral Portion of the Superior Aortic Recess Mimicking a Right Mediastinal Mass: Assessment with Chest Posterior Anterior and MDCT

    International Nuclear Information System (INIS)

    Shn, Dong Rock; Ryu, Dae Shick; Park, Man Soo; Jung, Seung Mun; Ahn, Jae Hong; Lee, Jong Hyeog; Choi, Soo Jung

    2012-01-01

    We observed patients in whom the fluid collection in the right lateral portion of the superior aortic recess on computed tomography (CT) scans mimicked a right anterior mediastinal mass on chest PA radiographs. The purpose of this study was to assess chest PA and CT features of these patients. All chest PA radiographs and CT scans in 9 patients were reviewed by two radiologists on a consensus basis; for the presence of pleural effusion, pulmonary edema and heart size on chest PA radiographs. For the portion of the fluid collection in the superior aortic recess (SAR), a connection between the right lateral portion of the SAR (rSAR) and posterior portion of the SAR (pSAR) on CT scans, and the distance between the right lateral margin of the rSAR and the right lateral margin of the superior vena cava. Fluid collection in the rSAR on CT scans caused a right anterior mediastinal mass or a bulging contour on chest PA radiographs in all women patients. All patients showed cardiomegaly, five patients had pleural effusion, and two patients had mild pulmonary edema. Further, eight patients showed a connection between the rSAR and the pSAR. The characteristic features of these patients are the right anterior mediastinal mass-like opacity due to fluid collection in the rSAR, are bulging contour with a smooth margin and cardiomegaly regardless of pulmonary edema on the chest PA radiographs, and fluid connection between the rSAR and the pSAR on CT scans

  3. Fluid Collection in the Right Lateral Portion of the Superior Aortic Recess Mimicking a Right Mediastinal Mass: Assessment with Chest Posterior Anterior and MDCT

    Energy Technology Data Exchange (ETDEWEB)

    Shn, Dong Rock; Ryu, Dae Shick; Park, Man Soo; Jung, Seung Mun; Ahn, Jae Hong; Lee, Jong Hyeog; Choi, Soo Jung [Dept. of Radiology, Gangneung Asan Hospital, College of Medicine, University of Ulsan, Gangneung (Korea, Republic of)

    2012-09-15

    We observed patients in whom the fluid collection in the right lateral portion of the superior aortic recess on computed tomography (CT) scans mimicked a right anterior mediastinal mass on chest PA radiographs. The purpose of this study was to assess chest PA and CT features of these patients. All chest PA radiographs and CT scans in 9 patients were reviewed by two radiologists on a consensus basis; for the presence of pleural effusion, pulmonary edema and heart size on chest PA radiographs. For the portion of the fluid collection in the superior aortic recess (SAR), a connection between the right lateral portion of the SAR (rSAR) and posterior portion of the SAR (pSAR) on CT scans, and the distance between the right lateral margin of the rSAR and the right lateral margin of the superior vena cava. Fluid collection in the rSAR on CT scans caused a right anterior mediastinal mass or a bulging contour on chest PA radiographs in all women patients. All patients showed cardiomegaly, five patients had pleural effusion, and two patients had mild pulmonary edema. Further, eight patients showed a connection between the rSAR and the pSAR. The characteristic features of these patients are the right anterior mediastinal mass-like opacity due to fluid collection in the rSAR, are bulging contour with a smooth margin and cardiomegaly regardless of pulmonary edema on the chest PA radiographs, and fluid connection between the rSAR and the pSAR on CT scans.

  4. Seismotectonics and fault structure of the California Central Coast

    Science.gov (United States)

    Hardebeck, Jeanne L.

    2010-01-01

    I present and interpret new earthquake relocations and focal mechanisms for the California Central Coast. The relocations improve upon catalog locations by using 3D seismic velocity models to account for lateral variations in structure and by using relative arrival times from waveform cross-correlation and double-difference methods to image seismicity features more sharply. Focal mechanisms are computed using ray tracing in the 3D velocity models. Seismicity alignments on the Hosgri fault confirm that it is vertical down to at least 12 km depth, and the focal mechanisms are consistent with right-lateral strike-slip motion on a vertical fault. A prominent, newly observed feature is an ~25 km long linear trend of seismicity running just offshore and parallel to the coastline in the region of Point Buchon, informally named the Shoreline fault. This seismicity trend is accompanied by a linear magnetic anomaly, and both the seismicity and the magnetic anomaly end where they obliquely meet the Hosgri fault. Focal mechanisms indicate that the Shoreline fault is a vertical strike-slip fault. Several seismicity lineations with vertical strike-slip mechanisms are observed in Estero Bay. Events greater than about 10 km depth in Estero Bay, however, exhibit reverse-faulting mechanisms, perhaps reflecting slip at the top of the remnant subducted slab. Strike-slip mechanisms are observed offshore along the Hosgri–San Simeon fault system and onshore along the West Huasna and Rinconada faults, while reverse mechanisms are generally confined to the region between these two systems. This suggests a model in which the reverse faulting is primarily due to restraining left-transfer of right-lateral slip.

  5. Focal dermal hypoplasia without focal dermal hypoplasia

    NARCIS (Netherlands)

    Contreras-Capetillo, Silvina N.; Lombardi, Maria Paola; Pinto-Escalante, Doris; Hennekam, Raoul C.

    2014-01-01

    Focal dermal hypoplasia (FDH; Goltz-Gorlin syndrome) is an X-linked dominant disorder affecting mainly tissues of ectodermal and mesodermal origin. The phenotype is characterized by hypoplastic linear skin lesions, eye malformations, hair and teeth anomalies, and multiple limbs malformations. The

  6. Analysis of Seismotektonic Patterns in Sumatra Region Based on the Focal Mechanism of Earthquake Period 1976-2016

    Science.gov (United States)

    Indah, F. P.; Syafriani, S.; Andiyansyah, Z. S.

    2018-04-01

    Sumatra is in an active subduction zone between the indo-australian plate and the eurasian plate and is located at a fault along the sumatra fault so that sumatra is vulnerable to earthquakes. One of the ways to find out the cause of earthquake can be done by identifying the type of earthquake-causing faults based on earthquake of focal mechanism. The data used to identify the type of fault cause of earthquake is the earth tensor moment data which is sourced from global cmt period 1976-2016. The data used in this research using magnitude m ≥ 6 sr. This research uses gmt software (generic mapping tolls) to describe the form of fault. From the research result, it is found that the characteristics of fault field that formed in every region in sumatera island based on data processing and data of earthquake history of 1976-2016 period that the type of fault in sumatera fault is strike slip, fault type in mentawai fault is reverse fault (rising faults) and dip-slip, while the fault type in the subduction zone is dip-slip.

  7. Evaluation of hypotheses for right-lateral displacement of Neogene strata along the San Andreas Fault between Parkfield and Maricopa, California

    Science.gov (United States)

    Stanley, Richard G.; Barron, John A.; Powell, Charles L.

    2017-12-22

    We used geological field studies and diatom biostratigraphy to test a published hypothesis that Neogene marine siliceous strata in the Maricopa and Parkfield areas, located on opposite sides of the San Andreas Fault, were formerly contiguous and then were displaced by about 80–130 kilometers (km) of right-lateral slip along the fault. In the Maricopa area on the northeast side of the San Andreas Fault, the upper Miocene Bitterwater Creek Shale consists of hard, siliceous shale with dolomitic concretions and turbidite sandstone interbeds. Diatom assemblages indicate that the Bitterwater Creek Shale was deposited about 8.0–6.7 million years before present (Ma) at the same time as the uppermost part of the Monterey Formation in parts of coastal California. In the Parkfield area on the southwest side of the San Andreas Fault, the upper Miocene Pancho Rico Formation consists of soft to indurated mudstone and siltstone and fossiliferous, bioturbated sandstone. Diatom assemblages from the Pancho Rico indicate deposition about 6.7–5.7 Ma (latest Miocene), younger than the Bitterwater Creek Shale and at about the same time as parts of the Sisquoc Formation and Purisima Formation in coastal California. Our results show that the Bitterwater Creek Shale and Pancho Rico Formation are lithologically unlike and of different ages and therefore do not constitute a cross-fault tie that can be used to estimate rightlateral displacement along the San Andreas Fault.In the Maricopa area northeast of the San Andreas Fault, the Bitterwater Creek Shale overlies conglomeratic fan-delta deposits of the upper Miocene Santa Margarita Formation, which in turn overlie siliceous shale of the Miocene Monterey Formation from which we obtained a diatom assemblage dated at about 10.0–9.3 Ma. Previous investigations noted that the Santa Margarita Formation in the Maricopa area contains granitic and metamorphic clasts derived from sources in the northern Gabilan Range, on the opposite side of

  8. Cholelithiasis with atrophy of the right lateral hepatic lobe in a horse Colelitíase com atrofia do lobo lateral direito em um cavalo

    Directory of Open Access Journals (Sweden)

    Renato de Lima Santos

    2007-04-01

    Full Text Available A 22 year-old horse developed cholelithiasis with marked atrophy of the right lateral hepatic lobe. The horse had a history of intermittent colic since three years of age, and one of the first episodes of colic was associated with icterus. The size of the right lateral hepatic lobe was extremely reduced. There was a large choledocholith in the common hepatic duct, and several hepatoliths and choleliths in the intra- and extra-hepatic billiary ducts. Microscopically, there was severe atrophy of the right lobe with diffuse proliferation of connective tissue and billiary ducts. The left lateral lobe had peri-portal fibrosis with proliferation of billiary ducts, and billiary stasis. Chemical analysis of the calculi detected amorphous and triple phosphate, bilirubin, calcium, and iron.Um cavalo de 22 anos de idade desenvolveu quadro de colelitíase severa com atrofia do lobo lateral direito. O animal tinha histórico de cólica recorrente, desde os três anos de idade, sendo que um dos primeiros episódios de cólica foi acompanhado de icterícia. O lobo hepático lateral direito estava extremamente diminuído de volume. Havia um grande coledocólito localizado no ducto hepático comum e inúmeros hepatólitos e colélitos nos ductos biliares intra e extra-hepáticos. Microscopicamente, foi observada atrofia acentuada do lobo direito, com proliferação difusa de tecido conjuntivo fibroso e de ductos biliares. O lobo lateral esquerdo apresentava fibrose periportal difusa associada à proliferação acentuada de ductos biliares e estase biliar. Análise química das concreções detectou fosfato triplo e amorfo, bilirrubina, cálcio e ferro.

  9. Analysis of Focal Mechanism and Microseismicity around the Lusi Mud Eruption Site, East Java, Indonesia

    Science.gov (United States)

    Karyono, Karyono; Obermann, Anne; Mazzini, Adriano; Lupi, Matteo; Syafri, Ildrem; Abdurrokhim, Abdurrokhim; Masturyono, Masturyono; Hadi, Soffian

    2016-04-01

    The 29th of May 2006 numerous eruption sites started in northeast Java, Indonesia following to a M6.3 earthquake striking the island.Within a few weeks an area or nearly 2 km2 was covered by boiling mud and rock fragments and a prominent central crater (named Lusi) has been erupting for the last 9.5 years. The M.6.3 seismic event also triggered the activation of the Watukosek strike slip fault system that originates from the Arjuno-Welirang volcanic complex and extends to the northeast of Java hosting Lusi and other mud volcanoes. Since 2006 this fault system has been reactivated in numerous instances mostly following to regional seismic and volcanic activity. However the mechanism controlling this activity have never been investigated and remain poorly understood. In order to investigate the relationship existing between seismicity, volcanism, faulting and Lusi activity, we have deployed a network of 31 seismometers in the framework of the ERC-Lusi Lab project. This network covers a large region that monitors the Lusi activity, the Watukosek fault system and the neighboring Arjuno-Welirang volcanic complex. In particular, to understand the consistent pattern of the source mechanism, relative to the general tectonic stress in the study area, a detailed analysis has been carried out by performing the moment tensor inversion for the near field data collected from the network stations. Furthermore these data have been combined with the near field data from the regional network of the Meteorological, Climatological and Geophysical Agency of Indonesia that covers the whole country on a broader scale. Keywords: Lusi, microseismic event, focal mechanism

  10. Focal retinal phlebitis.

    Science.gov (United States)

    Hoang, Quan V; Freund, K Bailey; Klancnik, James M; Sorenson, John A; Cunningham, Emmett T; Yannuzzi, Lawrence A

    2012-01-01

    To report three cases of solitary, focal retinal phlebitis. An observational case series. Three eyes in three patients were noted to have unilateral decreased vision, macular edema, and a focal retinal phlebitis, which was not at an arteriovenous crossing. All three patients developed a branch retinal vein occlusion at the site of inflammation. These patients had no other evidence of intraocular inflammation, including vitritis, retinitis, retinal vasculitis, or choroiditis, nor was there any systemic disorder associated with inflammation, infection, or coagulation identified. Focal retinal phlebitis appears to be an uncommon and unique entity that produces macular edema and ultimately branch retinal vein occlusion. In our patients, the focal phlebitis and venous occlusion did not occur at an arteriovenous crossing, which is the typical site for branch retinal venous occlusive disease. This suggests that our cases represent a distinct clinical entity, which starts with a focal abnormality in the wall of a retinal venule, resulting in surrounding exudation and, ultimately, ends with branch retinal vein occlusion.

  11. Using regional moment tensors to constrain the kinematics and stress evolution of the 2010–2013 Canterbury earthquake sequence, South Island, New Zealand

    Science.gov (United States)

    Herman, Matthew W.; Herrmann, Robert B.; Benz, Harley M.; Furlong, Kevin P.

    2014-01-01

    On September 3, 2010, a MW 7.0 (U.S. Geological Survey moment magnitude) earthquake ruptured across the Canterbury Plains in South Island, New Zealand. Since then, New Zealand GNS Science has recorded over 10,000 aftershocks ML 2.0 and larger, including three destructive ~ MW 6.0 earthquakes near Christchurch. We treat the Canterbury earthquake sequence as an intraplate earthquake sequence, and compare its kinematics to an Andersonian model for fault slip in a uniform stress field. We determined moment magnitudes and double couple solutions for 150 earthquakes having MW 3.7 and larger through the use of a waveform inversion technique using data from broadband seismic stations on South Island, New Zealand. The majority (126) of these double couple solutions have strike-slip focal mechanisms, with right-lateral slip on ENE fault planes or equivalently left-lateral slip on SSE fault planes. The remaining focal mechanisms indicate reverse faulting, except for two normal faulting events. The strike-slip segments have compatible orientations for slip in a stress field with a horizontal σ1 oriented ~ N115°E, and horizontal σ3. The preference for right lateral strike-slip earthquakes suggests that these structures are inherited from previous stages of deformation. Reverse slip is interpreted to have occurred on previously existing structures in regions with an absence of existing structures optimally oriented for strike-slip deformation. Despite the variations in slip direction and faulting style, most aftershocks had nearly the same P-axis orientation, consistent with the regional σ1. There is no evidence for significant changes in these stress orientations throughout the Canterbury earthquake sequence.

  12. Recurrent Bilateral Focal Myositis.

    Science.gov (United States)

    Nagafuchi, Hiroko; Nakano, Hiromasa; Ooka, Seido; Takakuwa, Yukiko; Yamada, Hidehiro; Tadokoro, Mamoru; Shimojo, Sadatomo; Ozaki, Shoichi

    This report describes a rare case of recurrent bilateral focal myositis and its successful treatment via methotrexate. A 38-year-old man presented myalgia of the right gastrocnemius in May 2005. Magnetic resonance imaging showed very high signal intensity in the right gastrocnemius on short-tau inversion recovery images. A muscle biopsy revealed inflammatory CD4+ cell-dominant myogenic change. Focal myositis was diagnosed. The first steroid treatment was effective. Tapering of prednisolone, however, repeatedly induced myositis relapse, which progressed to multiple muscle lesions of both lower limbs. Initiation of methotrexate finally allowed successful tapering of prednisolone, with no relapse in the past 4 years.

  13. Experimental Focal Cerebral Ischemia

    DEFF Research Database (Denmark)

    Christensen, Thomas

    2007-01-01

    Focal cerebral ischemia due to occlusion of a major cerebral artery is the cause of ischemic stroke which is a major reason of mortality, morbidity and disability in the populations of the developed countries. In the seven studies summarized in the thesis focal ischemia in rats induced by occlusion...... in the penumbra is recruited in the infarction process leading to a progressive growth of the infarct. The penumbra hence constitutes an important target for pharmacological treatment because of the existence of a therapeutic time window during which treatment with neuroprotective compounds may prevent...

  14. Minimally invasive right lateral thoracotomy without aortic cross-clamping: an attractive alternative to repeat sternotomy for reoperative mitral valve surgery.

    Science.gov (United States)

    Umakanthan, Ramanan; Petracek, Michael R; Leacche, Marzia; Solenkova, Nataliya V; Eagle, Susan S; Thompson, Annemarie; Ahmad, Rashid M; Greelish, James P; Ball, Stephen K; Hoff, Steven J; Absi, Tarek S; Balaguer, Jorge M; Byrne, John G

    2010-03-01

    The study aim was to determine the safety and benefits of minimally invasive mitral valve surgery without aortic cross-clamping for mitral valve surgery after previous cardiac surgery. Between January 2006 and August 2008, a total of 90 consecutive patients (38 females, 52 males; mean age 66 +/- 9 years) underwent minimally invasive mitral valve surgery after having undergone previous cardiac surgery. Of these patients, 80 (89%) underwent mitral valve replacement and 10 (11%) mitral valve repair utilizing a small (5 cm) right lateral thoracotomy along the 4th or 5th intercostal space under fibrillatory arrest (mean temperature 28 +/- 2 degrees C). The predicted mortality, calculated using the Society of Thoracic Surgeons (STS) algorithm, was compared to the observed mortality. The mean ejection fraction was 45 +/- 13%, mean NYHA class 3 +/- 1, while 66 patients (73%) had previous coronary artery bypass grafting and 37 (41%) had previous valve surgery. Twenty-six patients (29%) underwent non-elective surgery. Cardiopulmonary bypass was instituted through axillary (n = 19), femoral (n = 70) or direct use aortic (n = 1) cannulation. Operative mortality was 2% (2/90), lower than the STS-predicted mortality of 7%. Three patients (3%) developed acute renal failure postoperatively, one patient (1%) required new-onset hemodialysis, and one (1%) developed postoperative stroke. No patients developed postoperative myocardial infarction. The mean postoperative packed red blood cell transfusion requirement at 48 h was 2 +/- 3 units. Minimally invasive right thoracotomy without aortic cross-clamping is an excellent alternative to conventional redo-sternotomy for reoperative mitral valve surgery. The present study confirmed that this technique is safe and effective in reducing operative mortality in high-risk patients undergoing reoperative cardiac surgery.

  15. Active stress from earthquake focal mechanisms along the Padan-Adriatic side of the Northern Apennines (Italy), with considerations on stress magnitudes and pore-fluid pressures

    Science.gov (United States)

    Boncio, Paolo; Bracone, Vito

    2009-10-01

    The active tectonic regime along the outer Northern Apennines (Padan-Adriatic area) is a matter of debate. We analyse the active tectonic regime by systematically inverting earthquake focal mechanisms in terms of their driving stress field, comparing two different stress inversion methods. Earthquakes within the area often deviate from Andersonian conditions, being characterized by reverse or transpressional slip on high-angle faults even if the regime is almost purely thrust faulting (e.g. Reggio Emilia 1996 and Faenza 2000 earthquakes). We analyse the stress conditions at faulting for the Reggio Emilia and Faenza earthquakes in order to infer the stress magnitudes and the possible role of fluid pressures. The stress analysis defines a consistent pattern of sub-horizontal active deviatoric compression arranged nearly perpendicular to the eastern front of the Padan-Adriatic fold-and-thrust system, independent of the stress inversion method used. The results are consistent with active compression operating within the Padan-Adriatic belt. The stress field is thrust faulting (sub-vertical σ3), except for the Cesena-Forlì and Ancona areas, where a strike-slip regime (sub-vertical or steeply-plunging σ2) operates. The strike-slip regimes are interpreted as being caused by the superposition of local tensional stresses due to oroclinal bending (i.e. rotations of the belt about vertical axes) on the regional compressional stress field. Kinematic complexities characterize the 1996 Reggio Emilia seismic sequence. The distribution of these complexities is not random, suggesting that they are due to local variations of the regional stress field within the unfaulted rocks surrounding the coseismic rupture. The stress conditions at faulting for the Reggio Emilia 1996 and Faenza 2000 earthquakes, coupled with the observation that seismicity in the Padan-Adriatic area often occurs in swarms, suggest that high pore-fluid pressures (Pf ≥ 70% of the lithostatic load) operate

  16. The feature of the focal mechanism solutions and tectonic stress field around the focus of Zaduo earthquake (Ms 6.3) in eastern Tibet

    Science.gov (United States)

    Yang, Y.; Zeng, Z.; Shuang, X.; Li, X.

    2017-12-01

    On 17th October, 2016, an earthquake of Ms6.3 occurred in Zaduo County, Qinghai Province (32.9°N, 95.0°E), 159 km away from the epicenter of Yushu Ms7.3 earthquake in 2011. The earthquake is located in the eastern Tibet Plateau and the north region of Eastern Himalayan Syntaxis. Using the broadband seismic waveform data form regional networks, we determined the focal mechanism solutions (FMSs) of 83 earthquakes (M>3.5) occurred in Zaduo and its adjacent areas from 2009 to 2017. We also collected another 63 published FMSs and then inversed the current tectonic stress field in study region using the damped linear inversion method. The results show that the Zaduo earthquake is a normal oblique earthquake. The FMSs in our study region are mainly in strike-slip and normal fault patterns. The strike-slip earthquakes are mainly distributed in Yushu-Ganzi, Zaduo and Yanshiping fault zones, and the normal faulting events occurred in Nu Jiang fault zone and Nierong County and its vicinity, the south and southwest of the study areas. The tectonic stress field results indicate that the stress distribution in the north and east of the study region changes homogeneously and slowly. From west to east, the σ1 gradually changes from NNE to NE direction, and the σ3 varies from NWW to NW direction. Both the maximum (σ1) and minimum (σ3) principal stress axes in the study area are nearly horizontal, except in the Nu Jiang fault zone and its vicinity, the south of the study area, which is in a normal faulting stress regime (σ1 is vertical and σ3 is horizontal). The localized normal faulting stress field in the south area, which is almost limited in a semicircle, indicates that a high pressure and low viscosity body with low S-wave velocity and high conductivity might exists beneath the anomaly area. And there may be another semicircle abnormal area beyond the south of the study region. Waveform data for this study are provided by Data Management Centre of China National Seismic

  17. NW transverse fault system in Southern Bogota, Colombia: New seismologic and structural evidences derived from focal mechanisms and stress field determination

    Science.gov (United States)

    Angel Amaya, J.; Fierro Morales, J.; Ordoñez Potes, M.; Blanco, M.

    2012-12-01

    We present new seismological, morphotectonic and structural data of the Southern Bogota area. The goals of the study were to characterize the NW transverse fault system and to evaluate its effect on seismic wave's generation and propagation. The data set included epicenters of the RSNC (Red Sismologica Nacional de Colombia) catalog over the period 1993-2012, historical description of seismic events (period 1644-1921), structural field data (scale 1:100000) and remote sensors interpretation. The methodology included the structural analysis of over 476 faults having a known sense of offset by using a least squares iterative inversion outlined by Angelier (1984) to determinate the mean deviatoric principal stress tensor. Preliminary conclusions showed that both propagation medium and direction are determined by the structural and mechanic conditions of the Southern Bogota Shear Zone (SBSZ) defined by Fierro & Angel, (2008) as a NW-SE oblique-slip fault zone within sinistral and normal regimes. Based on both data sources (focal mechanism and field structural data) we attempted to reconstruct the stress field starting with a strike slip faulting stress regime (S2 vertical), the solution yielded a ENE-WSW orientation for horizontal principal stress (S1). It is hypothesized that the NW oblique-slip fault zone may generate and/or propagate seismic waves, as a local source, implying local hazard to Bogota the capital city of Colombia with over 8 million habitants.

  18. Focal myositis: A review.

    Science.gov (United States)

    Devic, P; Gallay, L; Streichenberger, N; Petiot, P

    2016-11-01

    Amongst the heterogeneous group of inflammatory myopathies, focal myositis stands as a rare and benign dysimmune disease. Although it can be associated with root and/or nerve lesions, traumatic muscle lesions and autoimmune diseases, its triggering factors remain poorly understood. Defined as an isolated inflammatory pseudotumour usually restricted to one skeletal muscle, clinical presentation of focal myositis is that of a rapidly growing solitary mass within a single muscle, usually in the lower limbs. Electromyography shows spontaneous activity associated with a myopathic pattern. MRI reveals a contrast enhanced enlarged muscle appearing hyper-intense on FAT-SAT T2 weighted images. Adjacent structures are spared and there are no calcifications. Serum creatine kinase (CK) levels are usually moderately augmented and biological markers of systemic inflammation are absent in most cases. Pathological histological features include marked variation in fibre size, inflammatory infiltrates mostly composed of T CD4+ lymphocytes and macrophages, degenerating/regenerating fibres and interstitial fibrosis. Differential diagnoses are numerous and include myositis of other origin with focal onset. Steroid treatment should be reserved for patients who present with major pain, nerve lesions, associated autoimmune disease, or elevated C reactive protein or CK. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Interactions between strike-slip earthquakes and the subduction interface near the Mendocino Triple Junction

    Science.gov (United States)

    Gong, Jianhua; McGuire, Jeffrey J.

    2018-01-01

    The interactions between the North American, Pacific, and Gorda plates at the Mendocino Triple Junction (MTJ) create one of the most seismically active regions in North America. The earthquakes rupture all three plate boundaries but also include considerable intraplate seismicity reflecting the strong internal deformation of the Gorda plate. Understanding the stress levels that drive these ruptures and estimating the locking state of the subduction interface are especially important topics for regional earthquake hazard assessment. However owing to the lack of offshore seismic and geodetic instruments, the rupture process of only a few large earthquakes near the MTJ have been studied in detail and the locking state of the subduction interface is not well constrained. In this paper, first, we use the second moments inversion method to study the rupture process of the January 28, 2015 Mw 5.7 earthquake on the Mendocino transform fault that was unusually well recorded by both onshore and offshore strong motion instruments. We estimate the rupture dimension to be approximately 6 km by 3 km corresponding to a stress drop of ∼4 MPa for a crack model. Next we investigate the frictional state of the subduction interface by simulating the afterslip that would be expected there as a result of the stress changes from the 2015 earthquake and a 2010 Mw 6.5 intraplate earthquake within the subducted Gorda plate. We simulate afterslip scenarios for a range of depths of the downdip end of the locked zone defined as the transition to velocity strengthening friction and calculate the corresponding surface deformation expected at onshore GPS monuments. We can rule out a very shallow downdip limit owing to the lack of a detectable signal at onshore GPS stations following the 2010 earthquake. Our simulations indicate that the locking depth on the slab surface is at least 14 km, which suggests that the next M8 earthquake rupture will likely reach the coastline and strong shaking should be expected there.

  20. E-W strike slip shearing of Kinwat Granitoid at South East Deccan ...

    Indian Academy of Sciences (India)

    53

    Environmental Science Trans. Royal Soc. Edin. ... Hydrogeology of Deccan Traps and associated formations in Penninsular India. Geol. Soc. ... India: constraints from geochronology, Nd–Sr isotopes and whole rock geochemistry. Precamb.

  1. E–W strike slip shearing of Kinwat granitoid at South East Deccan ...

    Indian Academy of Sciences (India)

    R D Kaplay

    2017-07-21

    Jul 21, 2017 ... Roy S and Rao R U M 1999 Geothermal investigations in the. 1993 Latur earthquake area, Deccan Volcanic Province,. India; Tectonophys. 306 237–252. Sangode S J, Mesharm D C, Kulkarni Y R, Gudadhe. S S, Malpe D B and Herlekar M A 2013 Neotectonic response of the Godavari and Kaddam Rivers ...

  2. Pseudodynamic Source Characterization for Strike-Slip Faulting Including Stress Heterogeneity and Super-Shear Ruptures

    KAUST Repository

    Mena, B.

    2012-08-08

    Reliable ground‐motion prediction for future earthquakes depends on the ability to simulate realistic earthquake source models. Though dynamic rupture calculations have recently become more popular, they are still computationally demanding. An alternative is to invoke the framework of pseudodynamic (PD) source characterizations that use simple relationships between kinematic and dynamic source parameters to build physically self‐consistent kinematic models. Based on the PD approach of Guatteri et al. (2004), we propose new relationships for PD models for moderate‐to‐large strike‐slip earthquakes that include local supershear rupture speed due to stress heterogeneities. We conduct dynamic rupture simulations using stochastic initial stress distributions to generate a suite of source models in the magnitude Mw 6–8. This set of models shows that local supershear rupture speed prevails for all earthquake sizes, and that the local rise‐time distribution is not controlled by the overall fault geometry, but rather by local stress changes on the faults. Based on these findings, we derive a new set of relations for the proposed PD source characterization that accounts for earthquake size, buried and surface ruptures, and includes local rise‐time variations and supershear rupture speed. By applying the proposed PD source characterization to several well‐recorded past earthquakes, we verify that significant improvements in fitting synthetic ground motion to observed ones is achieved when comparing our new approach with the model of Guatteri et al. (2004). The proposed PD methodology can be implemented into ground‐motion simulation tools for more physically reliable prediction of shaking in future earthquakes.

  3. Magmatic control along a strike-slip volcanic arc: The central Aeolian arc (Italy)

    KAUST Repository

    Ruch, Joel; Vezzoli, L.; De Rosa, R.; Di Lorenzo, R.; Acocella, V

    2016-01-01

    -slip motion; consistent with an E-W extension direction, with minor dextral and sinistral shear. Our data highlight six eruptive periods during the last 55 ka, which allow considering both islands as a single magmatic system, in which tectonic and magmatic

  4. Lithosphere evolution during the pre devonian of Uruguay: Prevalence of strike slip faults

    International Nuclear Information System (INIS)

    Bossi, J.

    2010-01-01

    The available data about mega shear zones were analyzed. Also the geo chronological trusty data about pre devonian rocks from Uruguay were overlapped. Emphasizing in the basic rocks, four tecto no-stratigraphy c terranes might be recognized. The approximate age of those rocks is known as well as the displacement trend. It can be concluded that the transmazonian age Piedra Alta Terrane (transmazonian age 2000 ± 100 My) is the most ancient block followed by the Tandilla Terrane (ages 2200 ± 100 My) which was joined through 1700 Ma. The Nico Perez Terrane displaced itself towards South generating the continental N10W mega shear fault Sarandi del Yi- Piriapolis towards 1250 My. Finally, the Arachania called continent made tangential collision from SE towards 525 Ma generating the ultramylonites band of the Sierra Ballena share zone. Each one of these terranes have totally different stratigraphy and lithological associations, and the chronological ages did not agree with the arrival of each one of the identified terranes

  5. Pseudodynamic Source Characterization for Strike-Slip Faulting Including Stress Heterogeneity and Super-Shear Ruptures

    KAUST Repository

    Mena, B.; Dalguer, L. A.; Mai, Paul Martin

    2012-01-01

    . (2004), we propose new relationships for PD models for moderate‐to‐large strike‐slip earthquakes that include local supershear rupture speed due to stress heterogeneities. We conduct dynamic rupture simulations using stochastic initial stress

  6. Domino structures evolution in strike-slip shear zones; the importance of the cataclastic flow

    Science.gov (United States)

    Moreira, N.; Dias, R.

    2018-05-01

    The Porto-Tomar-Ferreira do Alentejo dextral Shear Zone is one of the most important structures of the Iberian Variscides. In its vicinity, close to Abrantes (Central Portugal), a localized heterogeneous strain pattern developed in a decimetric metamorphic siliceous multilayer. This complex pattern was induced by the D2 dextral shearing of the early S0//S1 foliation in brittle-ductile conditions, giving rise to three main shear zone families. One of these families, with antithetic kinematics, delimits blocks with rigid clockwise rotation surrounded by coeval cataclasites, generating a local domino structure. The proposed geometrical and kinematic analysis, coupled with statistical studies, highlights the relation between subsidiary shear zones and the main shear zone. Despite the heterogeneous strain pattern, a quantitative approach of finite strain was applied based on the restoration of the initial fracture pattern. This approach shows the importance of the cataclastic flow coupled with the translational displacement of the domino domain in solving space problems related to the rigid block rotation. Such processes are key in allowing the rigid block rotation inside shear zones whenever the simple shear component is a fundamental mechanism.

  7. High Frequency Near-Field Ground Motion Excited by Strike-Slip Step Overs

    Science.gov (United States)

    Hu, Feng; Wen, Jian; Chen, Xiaofei

    2018-03-01

    We performed dynamic rupture simulations on step overs with 1-2 km step widths and present their corresponding horizontal peak ground velocity distributions in the near field within different frequency ranges. The rupture speeds on fault segments are determinant in controlling the near-field ground motion. A Mach wave impact area at the free surface, which can be inferred from the distribution of the ratio of the maximum fault-strike particle velocity to the maximum fault-normal particle velocity, is generated in the near field with sustained supershear ruptures on fault segments, and the Mach wave impact area cannot be detected with unsustained supershear ruptures alone. Sub-Rayleigh ruptures produce stronger ground motions beyond the end of fault segments. The existence of a low-velocity layer close to the free surface generates large amounts of high-frequency seismic radiation at step over discontinuities. For near-vertical step overs, normal stress perturbations on the primary fault caused by dipping structures affect the rupture speed transition, which further determines the distribution of the near-field ground motion. The presence of an extensional linking fault enhances the near-field ground motion in the extensional regime. This work helps us understand the characteristics of high-frequency seismic radiation in the vicinities of step overs and provides useful insights for interpreting the rupture speed distributions derived from the characteristics of near-field ground motion.

  8. Focal femoral condyle resurfacing.

    LENUS (Irish Health Repository)

    Brennan, S A

    2013-03-01

    Focal femoral inlay resurfacing has been developed for the treatment of full-thickness chondral defects of the knee. This technique involves implanting a defect-sized metallic or ceramic cap that is anchored to the subchondral bone through a screw or pin. The use of these experimental caps has been advocated in middle-aged patients who have failed non-operative methods or biological repair techniques and are deemed unsuitable for conventional arthroplasty because of their age. This paper outlines the implant design, surgical technique and biomechanical principles underlying their use. Outcomes following implantation in both animal and human studies are also reviewed. Cite this article: Bone Joint J 2013;95-B:301-4.

  9. Systemic focal epileptogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Remler, M.P.; Marcussen, W.H.

    1986-01-01

    Rats that receive radiation to 0.25 cc of one cerebral hemisphere are clinically and electroencephalographically normal until there is a breakdown of the blood-brain barrier (BBB) at 3 to 6 months postradiation. This BBB lesion can be detected by transient focal seizure activity produced by the BBB-excluded systemic convulsant bicuculline methiodide. In two rats the seizure activity induced by this one injection was self-sustaining. In seven of 15 other rats tested, the subsequent administration of repeated 2 mg/kg injections created a chronic focus that continued to spike with great frequency for 3 weeks or more without further administration of any convulsant. In three of eight other rats, implanted minipumps delivering 180 micrograms/h of bicuculline methiodide produced self-sustaining epileptic activity.

  10. Fast characterization of moment magnitude and focal mechanism in the context of tsunami warning in the NEAM region : W-phase and PDFM2 algorithms.

    Science.gov (United States)

    Schindelé, François; Roch, Julien; Duperray, Pierre; Reymond, Dominique

    2016-04-01

    Over past centuries, several large earthquakes (Mw ≥ 7.5) have been reported in the North East Atlantic and Mediterranenan sea (NEAM) region. Most of the tsunami potential seismic sources in the NEAM region, however, are in a magnitude range of 6.5 ≤ Mw ≤ 7.5 (e.g. tsunami triggered by the earthquake of Boumerdes in 2003 of Mw = 6.9). The CENALT (CENtre d'ALerte aux Tsunamis) in operation since 2012 as the French National Tsunami Warning Centre (NTWC) and Candidate Tsunami Service Provider (CTSP) has to issue warning messages within 15 minutes of the earthquake origin time. The warning level is currently based on a decision matrix depending on the magnitude, and the location of the hypocenter. Two seismic source inversion methods are implemented at CENALT: the W-phase algorithm, based on the so-called W-phase and PDFM2 algorithm , based on the surface waves and first P wave motions. They both give accurate moment magnitude and focal magnitude respectively in 10 min and 20 min. The results of the Mw magnitude, focal depth and type of fault (reverse, normal, strike-slip) are the most relevant parameters used to issue tsunami warnings. In this context, we assess the W-phase and PDFM2 methods with 29 events of magnitude Mw ≥ 5.8 for the period 2010-2015 in the NEAM region. Results with 10 and 20 min for the W-phase algorithm and with 20 and 30 min for the PDFM2 algorithm are compared to the Global Centroid Moment Tensor catalog. The W-phase and PDFM2 methods gives accurate results respectively in 10 min and 20 min. This work is funded by project ASTARTE -- Assessment, Strategy And Risk Reduction for Tsunamis in Europe - FP7-ENV2013 6.4-3, Grant 603839

  11. Focal midbrain tumors in children

    NARCIS (Netherlands)

    Vandertop, W. P.; Hoffman, H. J.; Drake, J. M.; Humphreys, R. P.; Rutka, J. T.; Amstrong, D. C.; Becker, L. E.

    1992-01-01

    The clinical and neuroradiological features of focal midbrain tumors in 12 children are described, and the results of their surgical management are presented. Patients with a focal midbrain tumor usually exhibit either symptoms and signs of raised intracranial pressure caused by an obstructive

  12. An Iterative Travel Time Inversion and Waveform Modeling Method to Determine the Crust Structure and Focal Mechanism: Case Study of 2015 Alxa Left Banner Ms5.8 Earthquake

    Science.gov (United States)

    Song, C.; Ge, Z.

    2017-12-01

    The boundary region between Alxa Block and Ordos Block is an area of stress concentration with strong seismicity and frequent small earthquakes. However, the knowledge of this area is limited since only a few seismic stations were deployed in this area. The 2015 Ms5.8 Alxa Left Banner Earthquake on April 15 is the largest one occurred in the surroundings since the 1976 Ms6.2 Bayinmuren Earthquake. Abundant stations built in the northern part of Chinese North-South Seismic Belt recorded this event sequence well within short distance, which provides us a great opportunity to carry out studies. We use these data to obtain a mean 1-D layered velocity structure via iterative inversion based on both travel time and waveform misfits. Then we use the travel time difference between data and synthetic seismograms to relocate the epicenter. Finally we invert the best double-couple focal mechanism and centroid depths of the source. As the result, the source is located at (39.7027° N, 106.4207° E) with a depth of 18 km and Mw 5.28. Nodal plane Ⅰ has strike 86°, dip angle 90° and slip angle -3°, while plane Ⅱ has strike 176°, dip angle 87° and slip angle 180°. Considering the dynamic structure of regional fault zone, we believe this earthquake is caused by a nearly pure left-lateral strike-slip fault with nodal plane Ⅰ being the fault plane. The seismogenic structure is likely to be an E-W striking buried fault nearby. There develops several groups of NE, NEE and E-W striking faults in Jilantai tectonic zone, parts of which have been verified by geophysical investigations. But we still know little about the dynamic nature of them. From our study, the corresponding fault of this event may indicate all groups of faults with same E-W strike has the common character of large-dip left-lateral strike-slip. Moreover, there may be some buried faults being newly born or not found yet. These results could be an important supplement to the future research of seismicity and

  13. Tectonic implications of the 2017 Ayvacık (Çanakkale) earthquakes, Biga Peninsula, NW Turkey

    Science.gov (United States)

    Özden, Süha; Över, Semir; Poyraz, Selda Altuncu; Güneş, Yavuz; Pınar, Ali

    2018-04-01

    The west to southwestward motion of the Anatolian block results from the relative motions between the Eurasian, Arabian and African plates along the right-lateral North Anatolian Fault Zone in the north and left-lateral East Anatolian Fault Zone in the east. The Biga Peninsula is tectonically influenced by the Anatolian motion originating along the North Anatolian Fault Zone which splits into two main (northern and southern) branches in the east of Marmara region: the southern branch extends towards the Biga Peninsula which is characterized by strike-slip to oblique normal faulting stress regime in the central to northern part. The southernmost part of peninsula is characterized by a normal to oblique faulting stress regime. The analysis of both seismological and structural field data confirms the change of stress regime from strike-slip character in the center and north to normal faulting character in the south of peninsula where the earthquake swarm recently occurred. The earthquakes began on 14 January 2017 (Mw: 4.4) on Tuzla Fault and migrated southward along the Kocaköy and Babakale's stepped-normal faults of over three months. The inversion of focal mechanisms yields a normal faulting stress regime with an approximately N-S (N4°E) σ3 axis. The inversion of earthquakes occurring in central and northern Biga Peninsula and the north Aegean region gives a strike-slip stress regime with approximately WNW-ESE (N85°W) σ1 and NNE-SSW (N17°E) σ3 axis. The strike-slip stress regime is attributed to westward Anatolian motion, while the normal faulting stress regime is attributed to both the extrusion of Anatolian block and the slab-pull force of the subducting African plate along the Hellenic arc.

  14. Diagnostic imaging in focal epilepsy

    International Nuclear Information System (INIS)

    Zlatareva, D.

    2013-01-01

    Focal epilepsies account for 60% of all seizure disorders worldwide. In this review the classic and new classification system of epileptic seizures and syndromes as well as genetic forms are discussed. Magnetic resonance (MR) is the technique of choice for diagnostic imaging in focal epilepsy because of its sensitivity and high tissue contrast. The review is focused on the lack of consensus of imaging protocols and reported findings in refractory epilepsy. The most frequently encountered MRI findings in epilepsy are reported and their imaging characteristics are depicted. Diagnosis of hippocampal sclerosis and malformations of cortical development as two major causes of refractory focal epilepsy is described in details. Some promising new techniques as positron emission tomography computed tomography (PET/CT) and MR and PET/CT fusion are briefly discussed. Also the relevance of adequate imaging in focal epilepsy, some practical points in imaging interpretation and differential diagnosis are highlighted. (author)

  15. Structure of the Hat Creek graben region: Implications for the structure of the Hat Creek graben and transfer of right-lateral shear from the Walker Lane north of Lassen Peak, northern California, from gravity and magnetic anomalies

    Science.gov (United States)

    Langenheim, Victoria; Jachens, Robert C.; Clynne, Michael A.; Muffler, L. J. Patrick

    2016-01-01

    Interpretation of magnetic and new gravity data provides constraints on the geometry of the Hat Creek Fault, the amount of right-lateral offset in the area between Mt. Shasta and Lassen Peak, and confirmation of the influence of pre-existing structure on Quaternary faulting. Neogene volcanic rocks coincide with short-wavelength magnetic anomalies of both normal and reversed polarity, whereas a markedly smoother magnetic field occurs over the Klamath Mountains and its Paleogene cover. Although the magnetic field over the Neogene volcanic rocks is complex, the Hat Creek Fault, which is one of the most prominent normal faults in the region and forms the eastern margin of the Hat Creek Valley, is marked by the eastern edge of a north-trending magnetic and gravity high 20-30 km long. Modeling of these anomalies indicates that the fault is a steeply dipping (~75-85°) structure. The spatial relationship of the fault as modeled by the potential-field data, the youngest strand of the fault, and relocated seismicity suggests that deformation continues to step westward across the valley, consistent with a component of right-lateral slip in an extensional environment. Filtered aeromagnetic data highlight a concealed magnetic body of Mesozoic or older age north of Hat Creek Valley. The body’s northwest margin strikes northeast and is linear over a distance of ~40 km. Within the resolution of the aeromagnetic data (1-2 km), we discern no right-lateral offset of this body. Furthermore, Quaternary faults change strike or appear to end, as if to avoid this concealed magnetic body and to pass along its southeast edge, suggesting that pre-existing crustal structure influenced younger faulting, as previously proposed based on gravity data.

  16. Continuously variable focal length lens

    Science.gov (United States)

    Adams, Bernhard W; Chollet, Matthieu C

    2013-12-17

    A material preferably in crystal form having a low atomic number such as beryllium (Z=4) provides for the focusing of x-rays in a continuously variable manner. The material is provided with plural spaced curvilinear, optically matched slots and/or recesses through which an x-ray beam is directed. The focal length of the material may be decreased or increased by increasing or decreasing, respectively, the number of slots (or recesses) through which the x-ray beam is directed, while fine tuning of the focal length is accomplished by rotation of the material so as to change the path length of the x-ray beam through the aligned cylindrical slows. X-ray analysis of a fixed point in a solid material may be performed by scanning the energy of the x-ray beam while rotating the material to maintain the beam's focal point at a fixed point in the specimen undergoing analysis.

  17. Testing of focal plane arrays

    International Nuclear Information System (INIS)

    Merriam, J.D.

    1988-01-01

    Problems associated with the testing of focal plane arrays are briefly examined with reference to the instrumentation and measurement procedures. In particular, the approach and instrumentation used as the Naval Ocean Systems Center is presented. Most of the measurements are made with flooded illumination on the focal plane array. The array is treated as an ensemble of individual pixels, data being taken on each pixel and array averages and standard deviations computed for the entire array. Data maps are generated, showing the pixel data in the proper spatial position on the array and the array statistics

  18. Right Lateral Cerebellum Represents Linguistic Predictability.

    Science.gov (United States)

    Lesage, Elise; Hansen, Peter C; Miall, R Chris

    2017-06-28

    Mounting evidence indicates that posterolateral portions of the cerebellum (right Crus I/II) contribute to language processing, but the nature of this role remains unclear. Based on a well-supported theory of cerebellar motor function, which ascribes to the cerebellum a role in short-term prediction through internal modeling, we hypothesize that right cerebellar Crus I/II supports prediction of upcoming sentence content. We tested this hypothesis using event-related fMRI in male and female human subjects by manipulating the predictability of written sentences. Our design controlled for motor planning and execution, as well as for linguistic features and working memory load; it also allowed separation of the prediction interval from the presentation of the final sentence item. In addition, three further fMRI tasks captured semantic, phonological, and orthographic processing to shed light on the nature of the information processed. As hypothesized, activity in right posterolateral cerebellum correlated with the predictability of the upcoming target word. This cerebellar region also responded to prediction error during the outcome of the trial. Further, this region was engaged in phonological, but not semantic or orthographic, processing. This is the first imaging study to demonstrate a right cerebellar contribution in language comprehension independently from motor, cognitive, and linguistic confounds. These results complement our work using other methodologies showing cerebellar engagement in linguistic prediction and suggest that internal modeling of phonological representations aids language production and comprehension. SIGNIFICANCE STATEMENT The cerebellum is traditionally seen as a motor structure that allows for smooth movement by predicting upcoming signals. However, the cerebellum is also consistently implicated in nonmotor functions such as language and working memory. Using fMRI, we identify a cerebellar area that is active when words are predicted and when these predictions are violated. This area is active in a separate task that requires phonological processing, but not in tasks that require semantic or visuospatial processing. Our results support the idea of prediction as a unifying cerebellar function in motor and nonmotor domains. We provide new insights by linking the cerebellar role in prediction to its role in verbal working memory, suggesting that these predictions involve phonological processing. Copyright © 2017 Lesage et al.

  19. Focal therapy in prostate cancer

    NARCIS (Netherlands)

    van den Bos, W.

    2016-01-01

    Interesting developments took place in the treatment of prostate cancer including focal therapy for less aggressive organ-confined prostate cancer. Fortunately, curative treatment is often still an option for patients suffering from the lower staged tumors. In carefully selected patients, the

  20. Gallbladder adenoma with focal adenocarcinoma.

    Science.gov (United States)

    Ciurea, S; Matei, E; Petrisor, P; Luca, L; Boros, Mirela; Herlea, V; Popescu, I

    2008-01-01

    The majority of polypoid lesions of the gallbladder are cholesterolosis pseudopolyps. True neoplastic GB polyps are represented mainly by adenomas. The case of a 52-year old male patient with an adenomatous polyp of the GB with focal adenocarcinoma is presented.

  1. Charging as a Focal Practice

    DEFF Research Database (Denmark)

    Bødker, Mads

    This position paper reflects on Borgmann’s notion of ‘focal things’ and its applicability in the discourse about interaction with technologies in nature. Using the example of a combined cooking burner and thermoelectric 5W smartphone charger (a BioLite cook stove), this position paper gives...

  2. Impairments in proverb interpretation following focal frontal lobe lesions☆

    Science.gov (United States)

    Murphy, Patrick; Shallice, Tim; Robinson, Gail; MacPherson, Sarah E.; Turner, Martha; Woollett, Katherine; Bozzali, Marco; Cipolotti, Lisa

    2013-01-01

    The proverb interpretation task (PIT) is often used in clinical settings to evaluate frontal “executive” dysfunction. However, only a relatively small number of studies have investigated the relationship between frontal lobe lesions and performance on the PIT. We compared 52 patients with unselected focal frontal lobe lesions with 52 closely matched healthy controls on a proverb interpretation task. Participants also completed a battery of neuropsychological tests, including a fluid intelligence task (Raven’s Advanced Progressive Matrices). Lesions were firstly analysed according to a standard left/right sub-division. Secondly, a finer-grained analysis compared the performance of patients with medial, left lateral and right lateral lesions with healthy controls. Thirdly, a contrast of specific frontal subgroups compared the performance of patients with medial lesions with patients with lateral frontal lesions. The results showed that patients with left frontal lesions were significantly impaired on the PIT, while in patients with right frontal lesions the impairments approached significance. Medial frontal patients were the only frontal subgroup impaired on the PIT, relative to healthy controls and lateral frontal patients. Interestingly, an error analysis indicated that a significantly higher number of concrete responses were found in the left lateral subgroup compared to healthy controls. We found no correlation between scores on the PIT and on the fluid intelligence task. Overall our results suggest that specific regions of the frontal lobes contribute to the performance on the PIT. PMID:23850600

  3. Impairments in proverb interpretation following focal frontal lobe lesions.

    Science.gov (United States)

    Murphy, Patrick; Shallice, Tim; Robinson, Gail; MacPherson, Sarah E; Turner, Martha; Woollett, Katherine; Bozzali, Marco; Cipolotti, Lisa

    2013-09-01

    The proverb interpretation task (PIT) is often used in clinical settings to evaluate frontal "executive" dysfunction. However, only a relatively small number of studies have investigated the relationship between frontal lobe lesions and performance on the PIT. We compared 52 patients with unselected focal frontal lobe lesions with 52 closely matched healthy controls on a proverb interpretation task. Participants also completed a battery of neuropsychological tests, including a fluid intelligence task (Raven's Advanced Progressive Matrices). Lesions were firstly analysed according to a standard left/right sub-division. Secondly, a finer-grained analysis compared the performance of patients with medial, left lateral and right lateral lesions with healthy controls. Thirdly, a contrast of specific frontal subgroups compared the performance of patients with medial lesions with patients with lateral frontal lesions. The results showed that patients with left frontal lesions were significantly impaired on the PIT, while in patients with right frontal lesions the impairments approached significance. Medial frontal patients were the only frontal subgroup impaired on the PIT, relative to healthy controls and lateral frontal patients. Interestingly, an error analysis indicated that a significantly higher number of concrete responses were found in the left lateral subgroup compared to healthy controls. We found no correlation between scores on the PIT and on the fluid intelligence task. Overall our results suggest that specific regions of the frontal lobes contribute to the performance on the PIT. © 2013 The Authors. Published by Elsevier Ltd. All rights reserved.

  4. Earthquake Rupture at Focal Depth, Part I: Structure and Rupture of the Pretorius Fault, TauTona Mine, South Africa

    Science.gov (United States)

    Heesakkers, V.; Murphy, S.; Reches, Z.

    2011-12-01

    We analyze the structure of the Archaean Pretorius fault in TauTona mine, South Africa, as well as the rupture-zone that recently reactivated it. The analysis is part of the Natural Earthquake Laboratory in South African Mines (NELSAM) project that utilizes the access to 3.6 km depth provided by the mining operations. The Pretorius fault is a ~10 km long, oblique-strike-slip fault with displacement of up to 200 m that crosscuts fine to very coarse grain quartzitic rocks in TauTona mine. We identify here three structural zones within the fault-zone: (1) an outer damage zone, ~100 m wide, of brittle deformation manifested by multiple, widely spaced fractures and faults with slip up to 3 m; (2) an inner damage zone, 25-30 m wide, with high density of anastomosing conjugate sets of fault segments and fractures, many of which carry cataclasite zones; and (3) a dominant segment, with a cataclasite zone up to 50 cm thick that accommodated most of the Archaean slip of the Pretorius fault, and is regarded as the `principal slip zone' (PSZ). This fault-zone structure indicates that during its Archaean activity, the Pretorius fault entered the mature fault stage in which many slip events were localized along a single, PSZ. The mining operations continuously induce earthquakes, including the 2004, M2.2 event that rejuvenated the Pretorius fault in the NELSAM project area. Our analysis of the M2.2 rupture-zone shows that (1) slip occurred exclusively along four, pre-existing large, quasi-planer segments of the ancient fault-zone; (2) the slipping segments contain brittle cataclasite zones up to 0.5 m thick; (3) these segments are not parallel to each other; (4) gouge zones, 1-5 mm thick, composed of white `rock-flour' formed almost exclusively along the cataclasite-host rock contacts of the slipping segments; (5) locally, new, fresh fractures branched from the slipping segments and propagated in mixed shear-tensile mode; (6) the maximum observed shear displacement is 25 mm in

  5. [Focal myositis: An unknown disease].

    Science.gov (United States)

    Gallay, L; Streichenberger, N; Benveniste, O; Allenbach, Y

    2017-10-01

    Focal myositis are inflammatory muscle diseases of unknown origin. At the opposite from the other idiopathic inflammatory myopathies, they are restricted to a single muscle or to a muscle group. They are not associated with extramuscular manifestations, and they have a good prognosis without any treatment. They are characterized by a localized swelling affecting mostly lower limbs. The pseudo-tumor can be painful, but is not associated with a muscle weakness. Creatine kinase level is normal. Muscle MRI shows an inflammation restricted to a muscle or a muscle group. Muscle biopsy and pathological analysis remain necessary for the diagnosis, showing inflammatory infiltrates composed by macrophages and lymphocytes without any specific distribution within the muscle. Focal overexpression of HLA-1 by the muscle fibers is frequently observed. The muscle biopsy permits to rule out differential diagnosis such a malignancy (sarcoma). Spontaneous remission occurs within weeks or months after the first symptoms, relapse is unusual. Copyright © 2017. Published by Elsevier SAS.

  6. Focal cortical dysplasia – review

    International Nuclear Information System (INIS)

    Kabat, Joanna; Król, Przemysław

    2012-01-01

    Focal cortical dysplasia is a malformation of cortical development, which is the most common cause of medically refractory epilepsy in the pediatric population and the second/third most common etiology of medically intractable seizures in adults. Both genetic and acquired factors are involved in the pathogenesis of cortical dysplasia. Numerous classifications of the complex structural abnormalities of focal cortical dysplasia have been proposed – from Taylor et al. in 1971 to the last modification of Palmini classification made by Blumcke in 2011. In general, three types of cortical dysplasia are recognized. Type I focal cortical dysplasia with mild symptomatic expression and late onset, is more often seen in adults, with changes present in the temporal lobe. Clinical symptoms are more severe in type II of cortical dysplasia usually seen in children. In this type, more extensive changes occur outside the temporal lobe with predilection for the frontal lobes. New type III is one of the above dysplasias with associated another principal lesion as hippocampal sclerosis, tumor, vascular malformation or acquired pathology during early life. Brain MRI imaging shows abnormalities in the majority of type II dysplasias and in only some of type I cortical dysplasias. The most common findings on MRI imaging include: focal cortical thickening or thinning, areas of focal brain atrophy, blurring of the gray-white junction, increased signal on T2- and FLAIR-weighted images in the gray and subcortical white matter often tapering toward the ventricle. On the basis of the MRI findings, it is possible to differentiate between type I and type II cortical dysplasia. A complete resection of the epileptogenic zone is required for seizure-free life. MRI imaging is very helpful to identify those patients who are likely to benefit from surgical treatment in a group of patients with drug-resistant epilepsy. However, in type I cortical dysplasia, MR imaging is often normal, and also in both

  7. Systems considerations in mosaic focal planes

    Science.gov (United States)

    White, K. P., III

    1983-08-01

    Two key reasons for pursuing the development of mosaic focal planes are reviewed and it is shown that rapid frame repetition rate is the only requirement that can be solved no other way than through mosaic focal planes. With the view that spaceborne mosaic focal plane sensors are necessarily 'smart sensors' requiring a lot of onboard processing just to function, it is pointed out that various artificial intelligence techniques may be the most appropriate to incorporate in the data processing. Finally, a novel mosaic focal plane design is proposed, termed a virtual mosaic focal plane, in response to other system constraints.

  8. TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly

    Science.gov (United States)

    Uchil, Pradeep D.; Pawliczek, Tobias; Reynolds, Tracy D.; Ding, Siyuan; Hinz, Angelika; Munro, James B.; Huang, Fang; Floyd, Robert W.; Yang, Haitao; Hamilton, William L.; Bewersdorf, Joerg; Xiong, Yong; Calderwood, David A.; Mothes, Walther

    2014-01-01

    ABSTRACT Focal adhesions are macromolecular complexes that connect the actin cytoskeleton to the extracellular matrix. Dynamic turnover of focal adhesions is crucial for cell migration. Paxillin is a multi-adaptor protein that plays an important role in regulating focal adhesion dynamics. Here, we identify TRIM15, a member of the tripartite motif protein family, as a paxillin-interacting factor and a component of focal adhesions. TRIM15 localizes to focal contacts in a myosin-II-independent manner by an interaction between its coiled-coil domain and the LD2 motif of paxillin. Unlike other focal adhesion proteins, TRIM15 is a stable focal adhesion component with restricted mobility due to its ability to form oligomers. TRIM15-depleted cells display impaired cell migration and reduced focal adhesion disassembly rates, in addition to enlarged focal adhesions. Thus, our studies demonstrate a cellular function for TRIM15 as a regulatory component of focal adhesion turnover and cell migration. PMID:25015296

  9. Heterogeneity of Focal Adhesions and Focal Contacts in Motile Fibroblasts.

    Science.gov (United States)

    Gladkikh, Aleena; Kovaleva, Anastasia; Tvorogova, Anna; Vorobjev, Ivan A

    2018-01-01

    Cell-extracellular matrix (ECM) adhesion is an important property of virtually all cells in multicellular organisms. Cell-ECM adhesion studies, therefore, are very significant both for biology and medicine. Over the last three decades, biomedical studies resulted in a tremendous advance in our understanding of the molecular basis and functions of cell-ECM adhesion. Based on morphological and molecular criteria, several different types of model cell-ECM adhesion structures including focal adhesions, focal complexes, fibrillar adhesions, podosomes, and three-dimensional matrix adhesions have been described. All the subcellular structures that mediate cell-ECM adhesion are quite heterogeneous, often varying in size, shape, distribution, dynamics, and, to a certain extent, molecular constituents. The morphological "plasticity" of cell-ECM adhesion perhaps reflects the needs of cells to sense, adapt, and respond to a variety of extracellular environments. In addition, cell type (e.g., differentiation status, oncogenic transformation, etc.) often exerts marked influence on the structure of cell-ECM adhesions. Although molecular, genetic, biochemical, and structural studies provide important maps or "snapshots" of cell-ECM adhesions, the area of research that is equally valuable is to study the heterogeneity of FA subpopulations within cells. Recently time-lapse observations on the FA dynamics become feasible, and behavior of individual FA gives additional information on cell-ECM interactions. Here we describe a robust method of labeling of FA using plasmids with fluorescent markers for paxillin and vinculin and quantifying the morphological and dynamical parameters of FA.

  10. Interferon Induced Focal Segmental Glomerulosclerosis

    Directory of Open Access Journals (Sweden)

    Yusuf Kayar

    2016-01-01

    Full Text Available Behçet’s disease is an inflammatory disease of unknown etiology which involves recurring oral and genital aphthous ulcers and ocular lesions as well as articular, vascular, and nervous system involvement. Focal segmental glomerulosclerosis (FSGS is usually seen in viral infections, immune deficiency syndrome, sickle cell anemia, and hyperfiltration and secondary to interferon therapy. Here, we present a case of FSGS identified with kidney biopsy in a patient who had been diagnosed with Behçet’s disease and received interferon-alpha treatment for uveitis and presented with acute renal failure and nephrotic syndrome associated with interferon.

  11. Focal nodular hyperplasia: imaging findings

    Energy Technology Data Exchange (ETDEWEB)

    Kehagias, D.; Moulopoulos, L.; Antoniou, A.; Hatziioannou, A.; Smyrniotis, V.; Trakadas, S.; Lahanis, S.; Vlahos, L. [Dept. of Radiology, University of Athens (Greece)

    2001-02-01

    Focal nodular hyperplasia is an uncommon benign hepatic tumor that continues to pose diagnostic dilemmas. Imaging techniques are of great value in diagnosis of this tumor. In this article we present the US, CT, MR imaging, scintigraphy, and angiography findings. The demonstration of a central vascular scar is very helpful. Although the radiologic features may be diagnostic, many atypical cases must be differentiated from other benign or malignant hepatic tumors. In these cases excisional biopsy and histopathologic examination are necessary to determine a definite diagnosis. (orig.)

  12. Focal nodular hyperplasia: imaging findings

    International Nuclear Information System (INIS)

    Kehagias, D.; Moulopoulos, L.; Antoniou, A.; Hatziioannou, A.; Smyrniotis, V.; Trakadas, S.; Lahanis, S.; Vlahos, L.

    2001-01-01

    Focal nodular hyperplasia is an uncommon benign hepatic tumor that continues to pose diagnostic dilemmas. Imaging techniques are of great value in diagnosis of this tumor. In this article we present the US, CT, MR imaging, scintigraphy, and angiography findings. The demonstration of a central vascular scar is very helpful. Although the radiologic features may be diagnostic, many atypical cases must be differentiated from other benign or malignant hepatic tumors. In these cases excisional biopsy and histopathologic examination are necessary to determine a definite diagnosis. (orig.)

  13. SNAP Satellite Focal Plane Development

    International Nuclear Information System (INIS)

    Bebek, C.; Akerlof, C.; Aldering, G.; Amanullah, R.; Astier, P.; Baltay, C.; Barrelet, E.; Basa, S.; Bercovitz, J.; Bergstrom, L.; Berstein, G.P.; Bester, M.; Bohlin, R.; Bonissent, A.; Bower, C.; Campbell, M.; Carithers, W.; Commins, E.; Day, C.; Deustua, S.; DiGennaro, R.; Ealet, A.; Ellis, R.; Emmett, W.; Eriksson, M.; Fouchez, D.; Fruchter, A.; Genat, J-F.; Goldhaber, G.; Goobar, A.; Groom, D.; Heetderks, H.; Holland, S.; Huterer, D.; Johnson, W.; Kadel, R.; Karcher, A.; Kim, A.; Kolbe, W.; Lafever, R.; Lamoureaux, J.; Lampton, M.; Lefevre, O.; Levi, M.; Levin, D.; Linder, E.; Loken, S.; Malina, R.; Mazure, A.; McKay, T.; McKee, S.; Miquel, R.; Morgan, N.; Mortsell, E.; Mostek, N.; Mufson, S.; Musser, J.; Roe, N.; Nugent, P.; Oluseyi, H.; Pain, R.; Palaio, N.; Pankow, D.; Perlmutter, S.; Prieto, E.; Rabinowitz, D.; Refregier, A.; Rhodes, J.; Schubnell, M.; Sholl, M.; Smadja, G.; Smith, R.; Smoot, G.; Snyder, J.; Spadafora, A.; Szymkowiak, A.; Tarle, G.; Taylor, K.; Tilquin, A.; Tomasch, A.; Vincent, D.; von der Lippe, H.; Walder, J-P.; Wang, G.

    2003-01-01

    The proposed SuperNova/Acceleration Probe (SNAP) mission will have a two-meter class telescope delivering diffraction-limited images to an instrumented 0.7 square degree field in the visible and near-infrared wavelength regime. The requirements for the instrument suite and the present configuration of the focal plane concept are presented. A two year R and D phase, largely supported by the Department of Energy, is just beginning. We describe the development activities that are taking place to advance our preparedness for mission proposal in the areas of detectors and electronics

  14. MRI of focal cortical dysplasia

    International Nuclear Information System (INIS)

    Lee, B.C.P.; Hatfield, G.A.; Bourgeois, B.; Park, T.S.

    1998-01-01

    We studied nine cases of focal cortical dysplasia (FCD) by MRI, with surface-rendered 3D reconstructions. One case was also examined using single-voxel proton MR spectroscopy (MRS). The histological features were reviewed and correlated with the MRI findings. The gyri affected by FCD were enlarged and the signal of the cortex was slightly increased on T1-weighted images. The gray-white junction was indistinct. Signal from the subcortical white matter was decreased on T1- and increased on T2-weighted images in most cases. Contrast enhancement was seen in two cases. Proton MRS showed a spectrum identical to that of normal brain. (orig.) (orig.)

  15. Pathogenesis of Focal Segmental Glomerulosclerosis

    Directory of Open Access Journals (Sweden)

    Beom Jin Lim

    2016-11-01

    Full Text Available Focal segmental glomerulosclerosis (FSGS is characterized by focal and segmental obliteration of glomerular capillary tufts with increased matrix. FSGS is classified as collapsing, tip, cellular, perihilar and not otherwise specified variants according to the location and character of the sclerotic lesion. Primary or idiopathic FSGS is considered to be related to podocyte injury, and the pathogenesis of podocyte injury has been actively investigated. Several circulating factors affecting podocyte permeability barrier have been proposed, but not proven to cause FSGS. FSGS may also be caused by genetic alterations. These genes are mainly those regulating slit diaphragm structure, actin cytoskeleton of podocytes, and foot process structure. The mode of inheritance and age of onset are different according to the gene involved. Recently, the role of parietal epithelial cells (PECs has been highlighted. Podocytes and PECs have common mesenchymal progenitors, therefore, PECs could be a source of podocyte repopulation after podocyte injury. Activated PECs migrate along adhesion to the glomerular tuft and may also contribute to the progression of sclerosis. Markers of activated PECs, including CD44, could be used to distinguish FSGS from minimal change disease. The pathogenesis of FSGS is very complex; however, understanding basic mechanisms of podocyte injury is important not only for basic research, but also for daily diagnostic pathology practice.

  16. Fault slip and earthquake recurrence along strike-slip faults — Contributions of high-resolution geomorphic data

    KAUST Repository

    Zielke, Olaf

    2015-01-01

    Understanding earthquake (EQ) recurrence relies on information about the timing and size of past EQ ruptures along a given fault. Knowledge of a fault\\'s rupture history provides valuable information on its potential future behavior, enabling seismic hazard estimates and loss mitigation. Stratigraphic and geomorphic evidence of faulting is used to constrain the recurrence of surface rupturing EQs. Analysis of the latter data sets culminated during the mid-1980s in the formulation of now classical EQ recurrence models, now routinely used to assess seismic hazard. Within the last decade, Light Detection and Ranging (lidar) surveying technology and other high-resolution data sets became increasingly available to tectono-geomorphic studies, promising to contribute to better-informed models of EQ recurrence and slip-accumulation patterns. After reviewing motivation and background, we outline requirements to successfully reconstruct a fault\\'s offset accumulation pattern from geomorphic evidence. We address sources of uncertainty affecting offset measurement and advocate approaches to minimize them. A number of recent studies focus on single-EQ slip distributions and along-fault slip accumulation patterns. We put them in context with paleoseismic studies along the respective faults by comparing coefficients of variation CV for EQ inter-event time and slip-per-event and find that a) single-event offsets vary over a wide range of length-scales and the sources for offset variability differ with length-scale, b) at fault-segment length-scales, single-event offsets are essentially constant, c) along-fault offset accumulation as resolved in the geomorphic record is dominated by essentially same-size, large offset increments, and d) there is generally no one-to-one correlation between the offset accumulation pattern constrained in the geomorphic record and EQ occurrence as identified in the stratigraphic record, revealing the higher resolution and preservation potential of the latter. While slip accumulation along a fault segment may be dominated by repetition of large, nearly constant offset increments, timing of surface-rupture is less regular. (C) 2014 Elsevier B.V. All rights reserved.

  17. Fault slip and earthquake recurrence along strike-slip faults — Contributions of high-resolution geomorphic data

    KAUST Repository

    Zielke, Olaf; Klinger, Yann; Arrowsmith, J. Ramon

    2015-01-01

    to contribute to better-informed models of EQ recurrence and slip-accumulation patterns. After reviewing motivation and background, we outline requirements to successfully reconstruct a fault's offset accumulation pattern from geomorphic evidence. We address

  18. Recurring extensional and strike-slip tectonics after the Neoproterozoic collisional events in the southern Mantiqueira province

    Directory of Open Access Journals (Sweden)

    Renato P. Almeida

    2012-06-01

    Full Text Available In Eastern South America, a series of fault-bounded sedimentary basins that crop out from Southern Uruguay to Southeastern Brazil were formed after the main collisional deformation of the Brasiliano Orogeny and record the tectonic events that affected the region from the Middle Ediacaran onwards. We address the problem of discerning the basin-forming tectonics from the later deformational events through paleostress analysis of more than 600 fault-slip data, mainly from the Camaquã Basin (Southern Brazil, sorted by stratigraphic level and cross-cutting relationships of superposed striations, and integrated with available stratigraphic and geochronological data. Our results show that the Camaquã Basin was formed by at least two distinct extensional events, and that rapid paleostress changes took place in the region a few tens of million years after the major collision (c.a. 630 Ma, probably due to the interplay between local active extensional tectonics and the distal effects of the continued amalgamation of plates and terranes at the margins of the still-forming Gondwana Plate. Preliminary paleostress data from the Castro Basin and published data from the Itajaí Basin suggest that these events had a regional nature.No Leste da América do Sul, um conjunto de bacias sedimentares que afloram do sul do Uruguai ao sudeste do Brasil formou-se após os eventos colisionais da Orogenia Brasiliana, registrando os eventos tectônicos que afetaram a região a partir do Mesoediacarano. O problema da distinção entre a tectônica formadora das bacias e os eventos deformacionais posteriores é aqui abordado através da análise de paleotensões de mais de 600 dados de falhas com estrias, obtidos principalmente na Bacia Camaquã (Sul do Brasil, que foram classificados por nível estratigráfico e relações de corte entre estrias sobrepostas, e intergrados a dados estratigráficos e geocronológicos disponíveis. Nossos resultados revelam que a Bacia Camaquã teve origem em ao menos dois eventos distensivos, e que modificações rápidas no campos de tensões ocorreram na região alguns poucos milhões de anos após a colisão principal (c.a. 630 Ma, provavelmente em decorrência da interação entre esforços distensivos locais e os efeitos distais da contínua amalgamação de placas e terrenos nas margens da placa Gondwana, ainda em formação. Dados preliminares de paleotensões da Bacia de Castro e dados publicados da Bacia Itajaí sugerem que esses eventos tiveram um caráter regional.

  19. RTG diagnostics of dental focal infection

    International Nuclear Information System (INIS)

    Petrasova, A.; Ondrasovicova, J.; Cecctkova, A.

    2008-01-01

    The theory of focal infection has always been and still is a controversial issue for many dentists and scientists. Even though the focal infection does not occupy the first place in modern medicine, its understanding is imperative. The authors summarized the knowledge about dental focal infection and its relationship to systemic the diseases of the whole body in their publication and they also focused on the radiodiagnostics of this disease. (authors)

  20. Periodontitis in patients with focal tuberculosis

    Directory of Open Access Journals (Sweden)

    Alexandrova Е.А.

    2010-12-01

    Full Text Available The research goal is to investigate the mechanisms of formation and peculiarities of periodontitis in patients with focal tuberculosis. Patients with periodontitis and focal tuberculosis are proved to develop local inflammatory reaction with increased infection and activation of proinflammatory cytokines in parodontal pockets fluid. The main risk factor of frequent and durable recurrence of parodontal pathology in case of focal tuberculosis was the development of pathologic process as a cause of disbalance of lipid peroxidation and antioxidant system, endotoxicosis syndrome

  1. Flux dynamics in ultrasensitive superconducting focal planes

    Data.gov (United States)

    National Aeronautics and Space Administration — The performance of superconducting focal planes will drive the achievable specifications of ultrasensitive instruments for NASA astrophysics missions, yet they have...

  2. Game Movement as Enactive Focalization

    Directory of Open Access Journals (Sweden)

    Yotam Shibolet

    2018-01-01

    Full Text Available This paper integrates thought on game narrative and embodied cognition, in order to consider the significance of movement to the embodied narrative experience of games. If games are a mode of ‘environmental storytelling’, determining the player’s mobile situatedness within the gamespace is of crucial importance. The metaphor of game design as narrative architecture should be expanded to include te the design of movement dynamics, alongside geographical gamespace. I suggest a theoretical infrastructure that aims to enable further analysis of movement design’s role in this scope. The theory of enactive perception asserts that all perception is inherently negotiated through embodied understanding of moving within environment. According to this model, by giving meaning to perception, movement is also directly related to the structure of consciousness and thought. Cognitive definitions of ‘narrative’ that integrate embodiment are applied to argue it can relevantly account for part of thought’s role in enactive perception. Mieke Bal’s concept of focalization (1997 broaches narrative perspective by underscoring the constant “movement of the look”. For enactive perception, such mobility should be understood as inseparable from the movement of the body even when perspective could appear detached from embodiment. Therefore, I offer the supplementary concept of “enactive focalization” – narrative perception as interpreted through the interconnected dynamics or perspectival and physical movement. To exemplify my ideas and the potential of future research in this scope, I discuss the uniquely effective and affective movement dynamic design of Journey. This paper concludes by reflecting on enactive focalization in light of the increased utilization of embodiment in the contemporary digital media landscape.

  3. Prenatal sonographic diagnosis of focal musculoskeletal anomalies

    Energy Technology Data Exchange (ETDEWEB)

    Ryu, Jung Kyu; Cho, Jeong Yeon; Lee, Young Ho; Kim, Ei Jeong; Chun, Yi Kyeong [Samsung Cheil Hospital, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2002-09-15

    Focal musculoskeletal anomalies are various and may be an isolated finding or may be found in conjunction with numerous associations, including genetic syndromes, Karyotype abnormals, central nervous system anomalies and other general musculoskeletal disorders. Early prenatal diagnosis of these focal musculoskeletal anomalies nor only affects prenatal care and postnatal outcome but also helps in approaching other numerous associated anomalies.

  4. Prenatal sonographic diagnosis of focal musculoskeletal anomalies

    International Nuclear Information System (INIS)

    Ryu, Jung Kyu; Cho, Jeong Yeon; Lee, Young Ho; Kim, Ei Jeong; Chun, Yi Kyeong

    2002-01-01

    Focal musculoskeletal anomalies are various and may be an isolated finding or may be found in conjunction with numerous associations, including genetic syndromes, Karyotype abnormals, central nervous system anomalies and other general musculoskeletal disorders. Early prenatal diagnosis of these focal musculoskeletal anomalies nor only affects prenatal care and postnatal outcome but also helps in approaching other numerous associated anomalies.

  5. Early vision and focal attention

    Science.gov (United States)

    Julesz, Bela

    1991-07-01

    At the thirty-year anniversary of the introduction of the technique of computer-generated random-dot stereograms and random-dot cinematograms into psychology, the impact of the technique on brain research and on the study of artificial intelligence is reviewed. The main finding-that stereoscopic depth perception (stereopsis), motion perception, and preattentive texture discrimination are basically bottom-up processes, which occur without the help of the top-down processes of cognition and semantic memory-greatly simplifies the study of these processes of early vision and permits the linking of human perception with monkey neurophysiology. Particularly interesting are the unexpected findings that stereopsis (assumed to be local) is a global process, while texture discrimination (assumed to be a global process, governed by statistics) is local, based on some conspicuous local features (textons). It is shown that the top-down process of "shape (depth) from shading" does not affect stereopsis, and some of the models of machine vision are evaluated. The asymmetry effect of human texture discrimination is discussed, together with recent nonlinear spatial filter models and a novel extension of the texton theory that can cope with the asymmetry problem. This didactic review attempts to introduce the physicist to the field of psychobiology and its problems-including metascientific problems of brain research, problems of scientific creativity, the state of artificial intelligence research (including connectionist neural networks) aimed at modeling brain activity, and the fundamental role of focal attention in mental events.

  6. Focal intramural pericardial effusion and cardiac tamponade associated with necrotic adipose tissue in a dog.

    Science.gov (United States)

    Krentz, Terence A; Schutrumpf, Robert J; Zitz, Julie C

    2017-07-15

    CASE DESCRIPTION A 1-year-old castrated male German Shepherd Dog was examined because of an acute onset of lethargy, tachypnea, and inappetence. CLINICAL FINDINGS On initial physical examination, the dog was tachypneic with muffled heart sounds on thoracic auscultation and a palpable abdominal fluid wave. Transthoracic echocardiography revealed focal intramural pericardial effusion and cardiac tamponade. TREATMENT AND OUTCOME The patient underwent emergency therapeutic pericardiocentesis, followed by right lateral intercostal thoracotomy and subtotal pericardiectomy. A 3 × 5-cm mass located between the parietal and visceral layers of the pericardium was resected. The histologic diagnosis was necrotic adipose tissue with granulomatous inflammation and fibroplasia. The patient also underwent exploratory laparotomy and umbilical herniorrhaphy during the same anesthetic episode and recovered from surgery without apparent complications. There were no further clinical signs of cardiac disease. CLINICAL RELEVANCE The patient described in the present report underwent successful subtotal pericardiectomy for treatment of a benign focal lesion causing recurrent pericardial effusion and cardiac tamponade. Prompt diagnosis and intervention may have contributed to the positive outcome in this case.

  7. Determination of Focal Mechanisms of Non-Volcanic Tremors Based on S-Wave Polarization Data Corrected for the Effects of Anisotropy

    Science.gov (United States)

    Imanishi, K.; Uchide, T.; Takeda, N.

    2014-12-01

    We propose a method to determine focal mechanisms of non-volcanic tremors (NVTs) based on S-wave polarization angles. The successful retrieval of polarization angles in low S/N tremor signals owes much to the observation that NVTs propagate slowly and therefore they do not change their location immediately. This feature of NVTs enables us to use a longer window to compute a polarization angle (e.g., one minute or longer), resulting in a stack of particle motions. Following Zhang and Schwartz (1994), we first correct for the splitting effect to recover the source polarization angle (anisotropy-corrected angle). This is a key step, because shear-wave splitting distorts the particle motion excited by a seismic source. We then determine the best double-couple solution using anisotropy-corrected angles of multiple stations. The present method was applied to a tremor sequence at Kii Peninsula, southwest Japan, which occurred at the beginning of April 2013. A standard splitting and polarization analysis were subject to a one-minute-long moving window to determine the splitting parameters as well as anisotropy-corrected angles. A grid search approach was performed at each hour to determine the best double-couple solution satisfying one-hour average polarization angles. Most solutions show NW-dipping low-angle planes consistent with the plate boundary or SE-dipping high-angle planes. Because of 180 degrees ambiguity in polarization angles, the present method alone cannot distinguish compressional quadrant from dilatational one. Together with the observation of very low-frequency earthquakes near the present study area (Ito et al., 2007), it is reasonable to consider that they represent shear slip on low-angle thrust faults. It is also noted that some of solutions contain strike-slip component. Acknowledgements: Seismograph stations used in this study include permanent stations operated by NIED (Hi-net), JMA, Earthquake Research Institute, together with Geological Survey of

  8. Focused seismicity triggered by flank instability on Kīlauea's Southwest Rift Zone

    Science.gov (United States)

    Judson, Josiah; Thelen, Weston A.; Greenfield, Tim; White, Robert S.

    2018-03-01

    Swarms of earthquakes at the head of the Southwest Rift Zone on Kīlauea Volcano, Hawai´i, reveal an interaction of normal and strike-slip faulting associated with movement of Kīlauea's south flank. A relocated subset of earthquakes between January 2012 and August 2014 are highly focused in space and time at depths that are coincident with the south caldera magma reservoir beneath the southern margin of Kīlauea Caldera. Newly calculated focal mechanisms are dominantly dextral shear with a north-south preferred fault orientation. Two earthquakes within this focused area of seismicity have normal faulting mechanisms, indicating two mechanisms of failure in very close proximity (10's of meters to 100 m). We suggest a model where opening along the Southwest Rift Zone caused by seaward motion of the south flank permits injection of magma and subsequent freezing of a plug, which then fails in a right-lateral strike-slip sense, consistent with the direction of movement of the south flank. The seismicity is concentrated in an area where a constriction occurs between a normal fault and the deeper magma transport system into the Southwest Rift Zone. Although in many ways the Southwest Rift Zone appears analogous to the more active East Rift Zone, the localization of the largest seismicity (>M2.5) within the swarms to a small volume necessitates a different model than has been proposed to explain the lineament outlined by earthquakes along the East Rift Zone.

  9. Microseismicity at the North Anatolian Fault in the Sea of Marmara offshore Istanbul, NW Turkey

    Science.gov (United States)

    Bulut, Fatih; Bohnhoff, Marco; Ellsworth, William L.; Aktar, Mustafa; Dresen, Georg

    2009-01-01

    The North Anatolian Fault Zone (NAFZ) below the Sea of Marmara forms a “seismic gap” where a major earthquake is expected to occur in the near future. This segment of the fault lies between the 1912 Ganos and 1999 İzmit ruptures and is the only NAFZ segment that has not ruptured since 1766. To monitor the microseismic activity at the main fault branch offshore of Istanbul below the Çınarcık Basin, a permanent seismic array (PIRES) was installed on the two outermost Prince Islands, Yassiada and Sivriada, at a few kilometers distance to the fault. In addition, a temporary network of ocean bottom seismometers was deployed throughout the Çınarcık Basin. Slowness vectors are determined combining waveform cross correlation and P wave polarization. We jointly invert azimuth and traveltime observations for hypocenter determination and apply a bootstrap resampling technique to quantify the location precision. We observe seismicity rates of 20 events per month for M etermine composite focal mechanisms implementing recordings of surrounding permanent land stations. Fault plane solutions have a predominant right-lateral strike-slip mechanism, indicating that normal faulting along this part of the NAFZ plays a minor role. Toward the west we observe increasing components of thrust faulting. This supports the model of NW trending, dextral strike-slip motion along the northern and main branch of the NAFZ below the eastern Sea of Marmara.

  10. Do focal colors look particularly "colorful"?

    Science.gov (United States)

    Witzel, Christoph; Franklin, Anna

    2014-04-01

    If the most typical red, yellow, green, and blue were particularly colorful (i.e., saturated), they would "jump out to the eye." This would explain why even fundamentally different languages have distinct color terms for these focal colors, and why unique hues play a prominent role in subjective color appearance. In this study, the subjective saturation of 10 colors around each of these focal colors was measured through a pairwise matching task. Results show that subjective saturation changes systematically across hues in a way that is strongly correlated to the visual gamut, and exponentially related to sensitivity but not to focal colors.

  11. Focal pancreatic enlargement: differentiation between pancreatic adenocarcinoma and focal pancreatitis on CT and ERCP

    International Nuclear Information System (INIS)

    Kim, Eun Kyung; Kim, Ki Whang; Lee, Jong Tae; Kim, Hee Soo; Yoo, Hyung Sik; Yu, Jeong Sik; Yoon, Sang Wook

    1995-01-01

    To differentiate the pancreatic adenocarcinoma from focal pancreatitis on CT and ERCP in cases of focal pancreatic enlargement. We analysed CT findings of 66 patients of pancreatic adenocarcinoma (n = 45) or focal pancreatitis (n = 21) with respect to size, density, calcification, pancreatic or biliary duct dilatation, fat plane obliteration around the vessels, direction of retroperitoneal extension, lymphadenopathy, pseudocyst formation and atrophy of pancreas. ERCP available in 48 patients were analysed in respect to morphologic appearance of CBD and pancreatic duct, and distance between the two ducts. The patients in focal pancreatitis were younger with more common history of alcohol drinking. There was no statistical difference in calcifications of the mass (18% in the adenocarcinoma, 33% in the focal pancreatitis), but a tendency of denser, larger number of calcifications was noted in focal pancreatitis. The finding of fat plane obliteration around the vessels were more common in pancreatic adenocarcinoma, and fascial thickenings were more prominent in focal pancreatitis, although not statistically significant. On ERCP, there were no differential points of CBD, pancreatic duct morphology, but distance between the two ducts at the lesion center was more wider in focal pancreatitis. Differentiating focal pancreatitis from pancreatic adenocarcinoma is difficult. However, we should consider the possibility of focal pancreatitis in cases of patients with young age, having alcoholic history in association with CT findings of large numbers of and dense calcifications, and ERCP findings of prominent separation of two duct at the lesion center

  12. Focal skin defect, limb anomalies and microphthalmia.

    NARCIS (Netherlands)

    Jackson, K.E.; Andersson, H.C.

    2004-01-01

    We describe two unrelated female patients with congenital single focal skin defects, unilateral microphthalmia and limb anomalies. Growth and psychomotor development were normal and no brain malformation was detected. Although eye and limb anomalies are commonly associated, clinical anophthalmia and

  13. Focal adhesions and cell-matrix interactions

    DEFF Research Database (Denmark)

    Woods, A; Couchman, J R

    1988-01-01

    Focal adhesions are areas of cell surfaces where specializations of cytoskeletal, membrane and extracellular components combine to produce stable cell-matrix interactions. The morphology of these adhesions and the components identified in them are discussed together with possible mechanisms...

  14. Genetics Home Reference: focal dermal hypoplasia

    Science.gov (United States)

    ... in people with focal dermal hypoplasia is an omphalocele , which is an opening in the wall of ... Dermal Hypoplasia MedlinePlus Encyclopedia: Ectodermal dysplasia MedlinePlus Encyclopedia: Omphalocele General Information from MedlinePlus (5 links) Diagnostic Tests ...

  15. Focal lesions in the central nervous system

    International Nuclear Information System (INIS)

    Fabrikant, J.I.; Budinger, T.F.; Tobias, C.A.; Born, J.L.

    1980-01-01

    This report reviews the animal and human studies currently in progress at LBL with heavy-ion beams to induce focal lesions in the central nervous system, and discusses the potential future prospects of fundamental and applied brain research with heavy-ion beams. Methods are being developed for producing discrete focal lesions in the central nervous system using the Bragg ionization peak to investigate nerve pathways and neuroendocrine responses, and for treating pathological disorders of the brain

  16. Sighting optics including an optical element having a first focal length and a second focal length

    Science.gov (United States)

    Crandall, David Lynn [Idaho Falls, ID

    2011-08-01

    One embodiment of sighting optics according to the teachings provided herein may include a front sight and a rear sight positioned in spaced-apart relation. The rear sight includes an optical element having a first focal length and a second focal length. The first focal length is selected so that it is about equal to a distance separating the optical element and the front sight and the second focal length is selected so that it is about equal to a target distance. The optical element thus brings into simultaneous focus, for a user, images of the front sight and the target.

  17. Transparent meta-analysis: does aging spare prospective memory with focal vs. non-focal cues?

    Directory of Open Access Journals (Sweden)

    Bob Uttl

    Full Text Available BACKGROUND: Prospective memory (ProM is the ability to become aware of a previously-formed plan at the right time and place. For over twenty years, researchers have been debating whether prospective memory declines with aging or whether it is spared by aging and, most recently, whether aging spares prospective memory with focal vs. non-focal cues. Two recent meta-analyses examining these claims did not include all relevant studies and ignored prevalent ceiling effects, age confounds, and did not distinguish between prospective memory subdomains (e.g., ProM proper, vigilance, habitual ProM (see Uttl, 2008, PLoS ONE. The present meta-analysis focuses on the following questions: Does prospective memory decline with aging? Does prospective memory with focal vs. non-focal cues decline with aging? Does the size of age-related declines with focal vs. non-focal cues vary across ProM subdomains? And are age-related declines in ProM smaller than age-related declines in retrospective memory? METHODS AND FINDINGS: A meta-analysis of event-cued ProM using data visualization and modeling, robust count methods, and conventional meta-analysis techniques revealed that first, the size of age-related declines in ProM with both focal and non-focal cues are large. Second, age-related declines in ProM with focal cues are larger in ProM proper and smaller in vigilance. Third, age-related declines in ProM proper with focal cues are as large as age-related declines in recall measures of retrospective memory. CONCLUSIONS: The results are consistent with Craik's (1983 proposal that age-related declines on ProM tasks are generally large, support the distinction between ProM proper vs. vigilance, and directly contradict widespread claims that ProM, with or without focal cues, is spared by aging.

  18. Focal thyroid inferno” on color Doppler ultrasonography: A specific feature of focal Hashimoto's thyroiditis

    International Nuclear Information System (INIS)

    Fu, Xianshui; Guo, Limei; Zhang, Huabin; Ran, Weiqiang; Fu, Peng; Li, Zhiqiang; Chen, Wen; Jiang, Ling; Wang, Jinrui; Jia, Jianwen

    2012-01-01

    Purpose: To evaluate color-Doppler features predictive of focal Hashimoto's thyroiditis. Materials and methods: A total of 521 patients with 561 thyroid nodules that underwent surgeries or gun biopsies were included in this study. These nodules were divided into three groups: focal Hashimoto's thyroiditis (104 nodules in 101 patients), benignity other than focal Hashimoto's thyroiditis (73 nodules in 70 patients), and malignancy (358 nodules in 350 patients). On color Doppler sonography, four vascularity types were determined as: hypovascularity, marked internal flow, marked peripheral flow and focal thyroid inferno. The χ 2 test was performed to seek the potential vascularity type with the predictive ability of certain thyroid pathology. Furthermore, the gray-scale features of each nodule were also studied. Results: The vascularity type I (hypovascularity) was more often seen in focal Hashimoto's thyroiditis than other benignity and malignancy (46% vs. 20.5% and 19%). While the type II (marked internal flow) showed the opposite tendency (26.9% [focal Hashimoto's thyroiditis] vs. 45.2% [other benignity] and 52.8% [malignancy]). However, type III (marked peripheral flow) was unable to predict any thyroid pathology. Importantly, type IV (focal thyroid inferno) was exclusive to focal Hashimoto's thyroiditis. All 8 type IV nodules appeared to be solid, hypoechoic, and well-defined. Using “focal thyroid inferno” as an indicator of FHT, the diagnostic sensitivity and specificity were 7.7% and 100% respectively. Conclusions: The vascularity type of “focal thyroid inferno” is specific for focal Hashimoto thyroiditis. Recognition of this particular feature may avoid unnecessary interventional procedures for some solid hypoechoic thyroid nodules suspicious of malignancy.

  19. Prenatal sonographic diagnosis of focal musculoskeletal anomalies

    International Nuclear Information System (INIS)

    Ryu, Jung-Kyu; Cho, Jeong-Yeon; Choi, Jong-Sun

    2003-01-01

    Focal musculoskeletal anomalies vary, and can manifest as part of a syndrome or be accompanied by numerous other conditions such as genetic disorders, karyotype abnormalities, central nervous system anomalies and other skeletal anomalies, lsolated focal musculoskeletal anomaly does, however, also occur; its early prenatal diagnosis is important in deciding prenatal care, and also helps in counseling parents about the postnatal effects of numerous possible associated anomalies. We have encountered 50 cases involving focal musculoskeletal anomalies, including total limb dysplasia [radial ray abnormality (n=3), mesomelic dysplasia (n=1)]; anomalies of the hand [polydactyly (n=8), syndactyly (n=3), ectrodactyly (n=1), clinodactyly (n=6), clenched hand (n=5)]; anomalies of the foot [clubfoot (n=10), rockerbottom foot (n=5), sandal gap deformity (n=1), curly toe (n=2)]; amniotic band syndrome (n=3); and anomalies of the focal spine [block vertebra (n=1), hemivertebra (n=1)]. Among these 50 cases, five [polydactyly (n=1), syndactyly (n=2) and curly toe (n=2) were confirmed by postnatal physical evaluation, two (focal spine anomalies) were diagnosed after postnatal radiologic examination, and the remaining 43 were proven at autopsy. For each condition, we describe the prenatal sonographic findings, and include a brief review

  20. Prenatal sonographic diagnosis of focal musculoskeletal anomalies

    Energy Technology Data Exchange (ETDEWEB)

    Ryu, Jung-Kyu; Cho, Jeong-Yeon; Choi, Jong-Sun [Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2003-12-15

    Focal musculoskeletal anomalies vary, and can manifest as part of a syndrome or be accompanied by numerous other conditions such as genetic disorders, karyotype abnormalities, central nervous system anomalies and other skeletal anomalies, lsolated focal musculoskeletal anomaly does, however, also occur; its early prenatal diagnosis is important in deciding prenatal care, and also helps in counseling parents about the postnatal effects of numerous possible associated anomalies. We have encountered 50 cases involving focal musculoskeletal anomalies, including total limb dysplasia [radial ray abnormality (n=3), mesomelic dysplasia (n=1)]; anomalies of the hand [polydactyly (n=8), syndactyly (n=3), ectrodactyly (n=1), clinodactyly (n=6), clenched hand (n=5)]; anomalies of the foot [clubfoot (n=10), rockerbottom foot (n=5), sandal gap deformity (n=1), curly toe (n=2)]; amniotic band syndrome (n=3); and anomalies of the focal spine [block vertebra (n=1), hemivertebra (n=1)]. Among these 50 cases, five [polydactyly (n=1), syndactyly (n=2) and curly toe (n=2) were confirmed by postnatal physical evaluation, two (focal spine anomalies) were diagnosed after postnatal radiologic examination, and the remaining 43 were proven at autopsy. For each condition, we describe the prenatal sonographic findings, and include a brief review.

  1. Seven tesla MRI improves detection of focal cortical dysplasia in patients with refractory focal epilepsy

    NARCIS (Netherlands)

    Veersema, Tim J; Ferrier, Cyrille H; van Eijsden, Pieter; Gosselaar, Peter H; Aronica, Eleonora; Visser, Fredy; Zwanenburg, Jaco M; de Kort, Gerard A P; Hendrikse, Jeroen; Luijten, Peter R; Braun, Kees P J

    Objective: The aim of this study is to determine whether the use of 7 tesla (T) MRI in clinical practice leads to higher detection rates of focal cortical dysplasias in possible candidates for epilepsy surgery. Methods: In our center patients are referred for 7 T MRI if lesional focal epilepsy is

  2. Expansive focal cemento-osseous dysplasia.

    Science.gov (United States)

    Bulut, Emel Uzun; Acikgoz, Aydan; Ozan, Bora; Zengin, Ayse Zeynep; Gunhan, Omer

    2012-01-01

    To present a case of expansive focal cemento-osseous dysplasia and emphasize the importance of differential diagnosis. Cemento-osseous dysplasia is categorized into three subtypes on the basis of the clinical and radiographic features: Periapical, focal and florid. The focal type exhibits a single site of involvement in any tooth-bearing or edentulous area of the jaws. These lesions are usually asymptomatic; therefore, they are frequently diagnosed incidentally during routine radiographic examinations. Lesions are usually benign, show limited growth, and do not require further surgical intervention, but periodic follow-up is recommended because occasionally, this type of dysplasia progresses into florid osseous dysplasia and simple bone cysts are formed. A 24-year-old female patient was referred to our clinic for swelling in the left edentulous mandibular premolarmolar region and felt discomfort when she wore her prosthetics. She had no pain, tenderness or paresthesia. Clinical examination showed that the swelling in the posterior mandible that was firm, nonfluctuant and covered by normal mucosa. On panoramic radiography and computed tomography, a well defined lesion of approximately 1.5 cm in diameter of mixed density was observed. The swelling increased slightly in size over 2 years making it difficult to use prosthetics and, therefore, the lesion was totally excised under local anesthesia, and surgical specimens were submitted for histopathological examination. The histopathological diagnosis was focal cemento-osseous dysplasia. In the present case, because of the increasing size of the swelling making it difficult to use prosthetics, young age of the patient and localization of the lesion, in the initial examination, cemento-ossifying fibroma was suspected, and the lesion was excised surgically; the histopathological diagnosis confirmed it as focal cemento-osseous dysplasia. We present a case of expansive focal cemento-osseous dysplasia. Differential diagnosis

  3. Extensive Focal Epithelial Hyperplasia: A Case Report.

    Science.gov (United States)

    Mansouri, Zahra; Bakhtiari, Sedigheh; Noormohamadi, Robab

    2015-01-01

    Focal epithelial hyperplasia (FEH) or Heck's disease is a rare viral infection of the oral mucosa caused by human papilloma virus especially subtypes 13 or 32. The frequency of this disease varies widely from one geographic region and ethnic groups to another. This paper reports an Iranian case of extensive focal epithelial hyperplasia. A 35-year-old man with FEH is described, in whom the lesions had persisted for more than 25 years. The lesion was diagnosed according to both clinical and histopathological features. Dental practitioner should be aware of these types of lesions and histopathological examination together and a careful clinical observation should be carried out for a definitive diagnosis.

  4. Rasmussen's encephalitis presenting as focal cortical dysplasia

    Directory of Open Access Journals (Sweden)

    D.J. O'Rourke

    2014-01-01

    Full Text Available Rasmussen's encephalitis is a rare syndrome characterized by intractable seizures, often associated with epilepsia partialis continua and symptoms of progressive hemispheric dysfunction. Seizures are usually the hallmark of presentation, but antiepileptic drug treatment fails in most patients and is ineffective against epilepsia partialis continua, which often requires surgical intervention. Co-occurrence of focal cortical dysplasia has only rarely been described and may have implications regarding pathophysiology and management. We describe a rare case of dual pathology of Rasmussen's encephalitis presenting as a focal cortical dysplasia (FCD and discuss the literature on this topic.

  5. Rasmussen's encephalitis presenting as focal cortical dysplasia

    Science.gov (United States)

    O'Rourke, D.J.; Bergin, A.; Rotenberg, A.; Peters, J.; Gorman, M.; Poduri, A.; Cryan, J.; Lidov, H.; Madsen, J.; Harini, C.

    2014-01-01

    Rasmussen's encephalitis is a rare syndrome characterized by intractable seizures, often associated with epilepsia partialis continua and symptoms of progressive hemispheric dysfunction. Seizures are usually the hallmark of presentation, but antiepileptic drug treatment fails in most patients and is ineffective against epilepsia partialis continua, which often requires surgical intervention. Co-occurrence of focal cortical dysplasia has only rarely been described and may have implications regarding pathophysiology and management. We describe a rare case of dual pathology of Rasmussen's encephalitis presenting as a focal cortical dysplasia (FCD) and discuss the literature on this topic. PMID:25667877

  6. Actinic Granuloma with Focal Segmental Glomerulosclerosis

    Directory of Open Access Journals (Sweden)

    Ruedee Phasukthaworn

    2016-02-01

    Full Text Available Actinic granuloma is an uncommon granulomatous disease, characterized by annular erythematous plaque with central clearing predominately located on sun-damaged skin. The pathogenesis is not well understood, ultraviolet radiation is recognized as precipitating factor. We report a case of a 52-year-old woman who presented with asymptomatic annular erythematous plaques on the forehead and both cheeks persisting for 2 years. The clinical presentation and histopathologic findings support the diagnosis of actinic granuloma. During that period of time, she also developed focal segmental glomerulosclerosis. The association between actinic granuloma and focal segmental glomerulosclerosis needs to be clarified by further studies.

  7. Focal splenic masses of the extramedullary hematopoiesis

    International Nuclear Information System (INIS)

    Incedayi, M.; Sivrioglu, A.

    2012-01-01

    Full text: Extramedullary hematopoiesis arises from pleuripotential stem cells distributed throughout the body. It is most common in patients with congenital hemolytic anemia, such as thalassemia, sickle cell anemia and hereditary spherocytosis as a response to ineffective red blood cell formation. Although microscopic foci of Extramedullary hematopoiesis are commonly seen in the spleen and liver parenchyma, focal mass-like lesion of extramedullary hematopoiesis in the liver and spleen are rare. We report a case of intrasplenic focal extramedullary hematopoiesis lesions and the imaging features of extramedullary hematopoiesis on computed tomography and magnetic resonance imaging. Extramedullary hematopoiesis should always be considered as a diagnosis in a patient with a known hematological disorder

  8. Infrared MUSIC from Z technology focal planes

    International Nuclear Information System (INIS)

    Waters, C.R.; Sommese, A.; Johnston, D.; Landau, H.

    1989-01-01

    Presented is the Multiple Signal Classification (MUSIC) algorithm which uses the high frequency differences in sensed time signals to discriminate, count, and accurately locate closely spaced targets. Z technology focal planes allow the implementation of this algorithm and the trade-off between finer spatial resolution systems and systems with coarser resolution but higher sampling rates

  9. Focal dermal hypoplasia: A rare case report

    Directory of Open Access Journals (Sweden)

    Sahana M Srinivas

    2015-01-01

    Full Text Available Focal dermal hypoplasia (Goltz syndrome is a rare genetic multisystem disorder primarily involving the skin, skeletal system, eyes, and face. We report the case of an eight-month-old female child who presented with multiple hypopigmented atrophic macules along the lines of blaschko, skeletal anomalies, umbilical hernia, developmental delay, hypoplastic nails, syndactyly, and lobster claw deformity characteristic of Goltz syndrome.

  10. DESI focal plate mechanical integration and cooling

    Science.gov (United States)

    Lambert, A. R.; Besuner, R. W.; Claybaugh, T. M.; Silber, J. H.

    2016-08-01

    The Dark Energy Spectroscopic Instrument (DESI) is under construction to measure the expansion history of the Universe using the Baryon Acoustic Oscillation technique[1]. The spectra of 40 million galaxies over 14000 sq. deg will be measured during the life of the experiment. A new prime focus corrector for the KPNO Mayall telescope will deliver light to 5000 fiber optic positioners. The fibers in turn feed ten broad-band spectrographs. This paper describes the mechanical integration of the DESI focal plate and the thermal system design. The DESI focal plate is comprised of ten identical petal assemblies. Each petal contains 500 robotic fiber positioners. Each petal is a complete, self-contained unit, independent from the others, with integrated power supply, controllers, fiber routing, and cooling services. The major advantages of this scheme are: (1) supports installation and removal of complete petal assemblies in-situ, without disturbing the others, (2) component production, assembly stations, and test procedures are repeated and parallelizable, (3) a complete, full-scale prototype can be built and tested at an early date, (4) each production petal can be surveyed and tested as a complete unit, prior to integration, from the fiber tip at the focal surface to the fiber slit at the spectrograph. The ten petal assemblies will be installed in a single integration ring, which is mounted to the DESI corrector. The aluminum integration ring attaches to the steel corrector barrel via a flexured steel adapter, isolating the focal plate from differential thermal expansions. The plate scale will be kept stable by conductive cooling of the petal assembly. The guider and wavefront sensors (one per petal) will be convectively cooled by forced flow of air. Heat will be removed from the system at ten liquid-cooled cold plates, one per petal, operating at ambient temperature. The entire focal plate structure is enclosed in an insulating shroud, which serves as a thermal barrier

  11. Radiopneumographic characteristics of focal pneumonia in children

    International Nuclear Information System (INIS)

    Smirnova, A.A.

    1980-01-01

    Zonal ventilation and blood flow were studied by the radiopneumography method in 50 children of school age with lower-lobe-of-the lung focal pneumonia (26 with left-side and 24 with right-side). It is established that during right-side localization of pneumonic focus preserved was the predomination of ventilation of right lung relative to left. Complete normalization of common and regional indexes of ventilation and blood flow was established by the 21st day from the beginning of treatment during right-side focal pneumonias. In case of left-side localization of pneumonic focus only partial reduction of external respiration and perfusion comes. Therefore, compensatory and reducing capabilities of right lung are preferrable

  12. Membership Functions for Fuzzy Focal Elements

    Directory of Open Access Journals (Sweden)

    Porębski Sebastian

    2016-09-01

    Full Text Available The paper presents a study on data-driven diagnostic rules, which are easy to interpret by human experts. To this end, the Dempster-Shafer theory extended for fuzzy focal elements is used. Premises of the rules (fuzzy focal elements are provided by membership functions which shapes are changing according to input symptoms. The main aim of the present study is to evaluate common membership function shapes and to introduce a rule elimination algorithm. Proposed methods are first illustrated with the popular Iris data set. Next experiments with five medical benchmark databases are performed. Results of the experiments show that various membership function shapes provide different inference efficiency but the extracted rule sets are close to each other. Thus indications for determining rules with possible heuristic interpretation can be formulated.

  13. Focal epilepsy in the Belgian shepherd

    DEFF Research Database (Denmark)

    Berendt, Mette; Gulløv, Christina Hedal; Fredholm, Merete

    2009-01-01

    and deceased) were ascertained through a telephone interview using a standardised questionnaire regarding seizure history and phenomenology. Living dogs were invited to a detailed clinical evaluation. Litters more than five years of age, or where epilepsy was present in all offspring before the age of five......, were included in the calculations of inheritance. results: Out of 199 family members, 66 dogs suffered from epilepsy. The prevalence of epilepsy in the family was 33%. Fifty-five dogs experienced focal seizures with or without secondary generalisation, while four dogs experienced primary generalised...... seizures. In seven dogs, seizures could not be classified. The mode of inheritance of epilepsy was simple Mendelian. CLINICAL SIGNIFICANCE: This study identified that the Belgian shepherd suffers from genetically transmitted focal epilepsy. The seizure phenomenology expressed by family members have...

  14. Chest pain in focal musculoskeletal disorders

    DEFF Research Database (Denmark)

    Stochkendahl, Mette Jensen; Christensen, Henrik Wulff

    2010-01-01

    overlapping conditions and syndromes of focal disorders, including Tietze syndrome, costochondritis, chest wall syndrome, muscle tenderness, slipping rib, cervical angina, and segmental dysfunction of the cervical and thoracic spine, have been reported to cause pain. For most of these syndromes, evidence......The musculoskeletal system is a recognized source of chest pain. However, despite the apparently benign origin, patients with musculoskeletal chest pain remain under-diagnosed, untreated, and potentially continuously disabled in terms of anxiety, depression, and activities of daily living. Several...... arises mainly from case stories and empiric knowledge. For segmental dysfunction, clinical features of musculoskeletal chest pain have been characterized in a few clinical trials. This article summarizes the most commonly encountered syndromes of focal musculoskeletal disorders in clinical practice....

  15. Characterization of LIL laser UV focal spot

    International Nuclear Information System (INIS)

    Mangeant, M.; Dubois, J.L.; Behar, G.; Arroyo, P.; Durand, V.; Lahonde, C.

    2006-01-01

    One way to get the fusion of hydrogen in laboratory consists in heating and compressing a DT fuel capsule by using a laser. To reach this aim requires a new generation of high power laser facility. Cea (French board for atomic energy) is developing for this purpose a new 240 laser line facility, the LMJ facility. The LIL which is the prototype of four LMJ laser lines is operational now. In order to confirm the technical choices, a systematic characterization of LIL was carried out. A particular effort has been provided to measure the 3ω high energy focal spot (1.5 kJ/700 ps and 5 ns for one beam) and the synchronization of laser beams onto the target, which are key issues for the plasma production. An experimental device, SAT-3ω (a 3ω laser focal spot analysis) has been designed to perform these measures. That diagnostic which is located at the end of the laser lines delivered its first results during the 2004 quadruplet qualification campaigns. The near field imaging showed no diaphony and vignetting. Low power spots allowed us to control we had no ghost. The energy measurement quality showed the photometric transfer function was perfectly known. Our caustic image are given with an average dynamic range of 800, a spatial resolution of 10 μm and diameter accuracy about 1% for 50% and 3% for 90% of encircled energy. The high energy focal spot diameters are in agreement with low and very low energy diameters. The phase plate and 14 GHz effects are similar to what we had expected. For a laser shot completed with a continuous phase plate at 14 GHz, and for an energy level of 1.5 kJ per beam at 351 nm, the focal beam diameter at 3% of the peak level is (875 ± 45) μm

  16. Proximal focal femoral deficiency: A case report

    Directory of Open Access Journals (Sweden)

    Shashank Sharma

    2015-01-01

    Full Text Available Proximal focal femoral deficiency (PFFD is a rare congenital anomaly resulting in limb shortening and disability in young. The exact cause of the disease is not known and it may present as varying grades of affection involving the proximal femur and the acetabulum. Recognition of this rare abnormality on radiographs can help manage these cases better since early institution of therapy may help in achieving adequate growth of the femur.

  17. Syndecan-4 and focal adhesion function

    DEFF Research Database (Denmark)

    Woods, A; Couchman, J R

    2001-01-01

    Two groups have now reported the viability of mice that lack syndecan-4. These mice have wound healing/angiogenesis problems, and fibroblasts from these animals differ in adhesion and migration from normal. This is consistent with recent in vitro data indicating a need for signaling via syndecan-4...... for focal adhesion formation, and reports that overexpression of proteins that bind syndecan-4 can modify cell adhesion and migration....

  18. Focal adhesions, stress fibers and mechanical tension

    Energy Technology Data Exchange (ETDEWEB)

    Burridge, Keith, E-mail: Keith_Burridge@med.unc.edu [Department of Cell Biology and Physiology, and Lineberger Comprehensive Cancer Center, 12-016 Lineberger, CB#7295, University of North Carolina, Chapel Hill, NC (United States); Guilluy, Christophe, E-mail: christophe.guilluy@univ-nantes.fr [Inserm UMR-S1087, CNRS UMR-C6291, L' institut du Thorax, and Université de Nantes, Nantes (France)

    2016-04-10

    Stress fibers and focal adhesions are complex protein arrays that produce, transmit and sense mechanical tension. Evidence accumulated over many years led to the conclusion that mechanical tension generated within stress fibers contributes to the assembly of both stress fibers themselves and their associated focal adhesions. However, several lines of evidence have recently been presented against this model. Here we discuss the evidence for and against the role of mechanical tension in driving the assembly of these structures. We also consider how their assembly is influenced by the rigidity of the substratum to which cells are adhering. Finally, we discuss the recently identified connections between stress fibers and the nucleus, and the roles that these may play, both in cell migration and regulating nuclear function. - Highlights: • The different types of stress fiber and focal adhesion are described. • We discuss the controversy about tension and assembly of these structures. • We describe the different models used to investigate assembly of these structures. • The influence of substratum rigidity is discussed. • Stress fiber connections to the nucleus are reviewed.

  19. Focal plane scanner with reciprocating spatial window

    Science.gov (United States)

    Mao, Chengye (Inventor)

    2000-01-01

    A focal plane scanner having a front objective lens, a spatial window for selectively passing a portion of the image therethrough, and a CCD array for receiving the passed portion of the image. All embodiments have a common feature whereby the spatial window and CCD array are mounted for simultaneous relative reciprocating movement with respect to the front objective lens, and the spatial window is mounted within the focal plane of the front objective. In a first embodiment, the spatial window is a slit and the CCD array is one-dimensional, and successive rows of the image in the focal plane of the front objective lens are passed to the CCD array by an image relay lens interposed between the slit and the CCD array. In a second embodiment, the spatial window is a slit, the CCD array is two-dimensional, and a prism-grating-prism optical spectrometer is interposed between the slit and the CCD array so as to cause the scanned row to be split into a plurality of spectral separations onto the CCD array. In a third embodiment, the CCD array is two-dimensional and the spatial window is a rectangular linear variable filter (LVF) window, so as to cause the scanned rows impinging on the LVF to be bandpass filtered into spectral components onto the CCD array through an image relay lens interposed between the LVF and the CCD array.

  20. Classification of Focal and Non Focal Epileptic Seizures Using Multi-Features and SVM Classifier.

    Science.gov (United States)

    Sriraam, N; Raghu, S

    2017-09-02

    Identifying epileptogenic zones prior to surgery is an essential and crucial step in treating patients having pharmacoresistant focal epilepsy. Electroencephalogram (EEG) is a significant measurement benchmark to assess patients suffering from epilepsy. This paper investigates the application of multi-features derived from different domains to recognize the focal and non focal epileptic seizures obtained from pharmacoresistant focal epilepsy patients from Bern Barcelona database. From the dataset, five different classification tasks were formed. Total 26 features were extracted from focal and non focal EEG. Significant features were selected using Wilcoxon rank sum test by setting p-value (p z > 1.96) at 95% significance interval. Hypothesis was made that the effect of removing outliers improves the classification accuracy. Turkey's range test was adopted for pruning outliers from feature set. Finally, 21 features were classified using optimized support vector machine (SVM) classifier with 10-fold cross validation. Bayesian optimization technique was adopted to minimize the cross-validation loss. From the simulation results, it was inferred that the highest sensitivity, specificity, and classification accuracy of 94.56%, 89.74%, and 92.15% achieved respectively and found to be better than the state-of-the-art approaches. Further, it was observed that the classification accuracy improved from 80.2% with outliers to 92.15% without outliers. The classifier performance metrics ensures the suitability of the proposed multi-features with optimized SVM classifier. It can be concluded that the proposed approach can be applied for recognition of focal EEG signals to localize epileptogenic zones.

  1. Multispectral linear array (MLA) focal plane mechanical and thermal design

    Science.gov (United States)

    Mitchell, A. S.; Kaminski, E. F.

    1982-01-01

    The mechanical and thermal design of an integrated focal plane subsystem of a Multispectral Linear Array (MLA) instrument is discussed in terms of focal-plane alignment, thermoelastic performance, and thermal requirements. The modular construction and thermal control of the focal plane array are discussed.

  2. Geodynamics and Stress State of the Earth's Crust in the Greater and Lesser Caucasus (Azerbaijan) collision region

    Science.gov (United States)

    Babayev, Gulam; Akhmedova, Elnare; Babayev, Elvin

    2017-04-01

    The current study researches the present-day stress state of the Earth's crust within the territory of Azerbaijan by using the database of the international research project "World Stress Map" (WSM). The present stress state was also assessed by exploring the effects of the contemporary topographic properties of Caucasus in three-dimensional frame. Aiming to explore the relative roles of regional tectonic conditions in the definition of stress state of Greater and Lesser Caucasus, stress distribution model was developed by the earthquake data (1998-2016) and by the standard techniques of stress field calculation. The results show that the stress orientations are influenced also by the combination of topography and crust thickness distribution even at very large depth. Stress data and earthquake focal mechanisms indicate that the stress state of the Earth's crust of the Greater and Lesser Caucasus is characterized by the compression predominantly oriented across the regional strike. The model results suggest that the Lesser Caucasus and Kur depression are rotating coherently, with little or no internal deformation in a counter-clockwise rotation located near the north-eastern corner of the Black Sea. Orientation of stress axes well consistent with earthquake focal mechanisms revealed that within Upper and Lower Crusts, earthquakes are predominantly thrust-faulting with a number of normal-faulting and some strike-slip faulting. The map of the focal mechanisms and stress distribution suggests that the research area is characterized by the thrust of horizontal compression trending north-north-east in the western part of the southern Caucasus. In the western part of Azerbaijan, the compression takes place between the Main Caucasus Fault and the Kur depression, which strikes south along the northern margin of the mountain range. In addition, a clear transition from the left-lateral strike slip to the predominantly right-lateral strike slip is observed in the southern of

  3. High-Precision Locations and the Stress Field from Instrumental Seismicity, Moment Tensors, and Short-Period Mechanisms through the Mina Deflection, Central Walker Lane

    Science.gov (United States)

    Ruhl, C. J.; Smith, K. D.

    2012-12-01

    The Mina Deflection (MD) region of the central Walker Lane of eastern California and western Nevada, is a complex zone of northeast-trending normal, and primarily left-lateral strike-slip to oblique-slip faulting that separates the Southern Walker Lane (SWL) from a series of east-tilted normal fault blocks in the Central Walker Lane (CWL) (Faulds and Henry, 2008; Surpless, 2008). The MD accommodates the transfer of right-lateral strike-slip motion from northwest-striking faults in the SWL to a series of left-stepping northwest-striking right-lateral strike-slip faults in the CWL, east of the Wassuk Range near Hawthorne, NV. The ~50 km wide ~80 km long right-step is a distinct transition in regional physiography that has been attributed to strain accommodation through pre-Cenozoic lithospheric structures. Several slip transfer mechanisms have been proposed within the MD, from clockwise rotation of high-angle fault blocks (Wesnousky, 2005), to low-angle displacement within the Silver Peak-Lone Mountain complex (Oldow et al., 2001), and curved fault arrays associated with localized basins and tectonic depressions (Ferranti et al., 2009). The region has been a regular source of M4+ events, the most recent being an extended sequence that included twenty-seven M 3.5+ earthquakes (largest event M 4.6) south of Hawthorne in 2011. These earthquakes (Mina, NV, and the 1932 M 7.1 Cedar Mountains earthquake east of the Pilot Mountains. Another persistent feature in the seismicity is an ~40 km long arcuate distribution of activity extending from approximately Queen Valley, north of the White Mountains, to Mono Lake that appears to reflect a southwestern boundary to northeast-striking structures in the MD. Here we develop high-precision relocations of instrumental seismicity in the MD from 1984 through 2012, including relocations of the 2004 sequence, and account for the historical seismic record. MT solutions from published reports and computed from recent M 3.5+ earthquakes as

  4. The Simbol-X Focal Plane

    Science.gov (United States)

    Laurent, P.

    2009-05-01

    The Simbol-X focal plane is designed to detect photons focused by the mirror in the 0.5 to 100 keV energy band. Composed of two detectors, it will measure the position, energy, and arrival time of each incoming X-ray. On top of it will be a collimator to shield all photons not coming from the mirror field of view. The whole system is surrounded by an active and passive shielding in order to ensure the required very low background.

  5. Focal inflammatory diseases of the liver

    International Nuclear Information System (INIS)

    Oto, Aytekin; Akhan, Okan; Oezmen, Mustafa

    1999-01-01

    Inflammatory lesions constitute an important subgroup of focal liver lesions. They may mimic primary or metastatic neoplastic lesions and their differentiation from neoplasia is clinically very important since management of the patient significantly changes. Radiologists should have an important role in both the diagnosis and therapy of these lesions by performing percutaneous aspirations and drainages. In this review we discussed the radiological findings of pyogenic abscesses, amebic abscesses, candidiasis, tuberculosis, hydatic cysts, fascioliasis, ascariasis, schistosomiasis, and sarcoidosis with a special emphasis on US, CT and MR characteristics

  6. Focal inflammatory diseases of the liver

    Energy Technology Data Exchange (ETDEWEB)

    Oto, Aytekin; Akhan, Okan; Oezmen, Mustafa

    1999-10-01

    Inflammatory lesions constitute an important subgroup of focal liver lesions. They may mimic primary or metastatic neoplastic lesions and their differentiation from neoplasia is clinically very important since management of the patient significantly changes. Radiologists should have an important role in both the diagnosis and therapy of these lesions by performing percutaneous aspirations and drainages. In this review we discussed the radiological findings of pyogenic abscesses, amebic abscesses, candidiasis, tuberculosis, hydatic cysts, fascioliasis, ascariasis, schistosomiasis, and sarcoidosis with a special emphasis on US, CT and MR characteristics.

  7. Characterization of DECam focal plane detectors

    Energy Technology Data Exchange (ETDEWEB)

    Diehl, H.Thomas; Angstadt, Robert; Campa, Julia; Cease, Herman; Derylo, Greg; Emes, John H.; Estrada, Juan; Kibik, Donna; Flaugher, Brenna L.; Holland, Steve E.; Jonas, Michelle; /Fermilab /Madrid, CIEMAT /LBL, Berkeley /Argonne /Pennsylvania U.

    2008-06-01

    DECam is a 520 Mpix, 3 square-deg FOV imager being built for the Blanco 4m Telescope at CTIO. This facility instrument will be used for the 'Dark Energy Survey' of the southern galactic cap. DECam has chosen 250 ?m thick CCDs, developed at LBNL, with good QE in the near IR for the focal plane. In this work we present the characterization of these detectors done by the DES team, and compare it to the DECam technical requirements. The results demonstrate that the detectors satisfy the needs for instrument.

  8. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Pseudotachylytes, as well as the country rock, bear the evidence of conjugate strike slip shearing along NNE–SSW and NW–SE directions, suggesting an N–S compression. The Gangavalli Shear Zone represents the NNE–SSW fault of the conjugate system along which a right lateral shear has produced seismic slip motion ...

  9. Idiopathic focal epilepsies: the "lost tribe".

    Science.gov (United States)

    Pal, Deb K; Ferrie, Colin; Addis, Laura; Akiyama, Tomoyuki; Capovilla, Giuseppe; Caraballo, Roberto; de Saint-Martin, Anne; Fejerman, Natalio; Guerrini, Renzo; Hamandi, Khalid; Helbig, Ingo; Ioannides, Andreas A; Kobayashi, Katsuhiro; Lal, Dennis; Lesca, Gaetan; Muhle, Hiltrud; Neubauer, Bernd A; Pisano, Tiziana; Rudolf, Gabrielle; Seegmuller, Caroline; Shibata, Takashi; Smith, Anna; Striano, Pasquale; Strug, Lisa J; Szepetowski, Pierre; Valeta, Thalia; Yoshinaga, Harumi; Koutroumanidis, Michalis

    2016-09-01

    The term idiopathic focal epilepsies of childhood (IFE) is not formally recognised by the ILAE in its 2010 revision (Berg et al., 2010), nor are its members and boundaries precisely delineated. The IFEs are amongst the most commonly encountered epilepsy syndromes affecting children. They are fascinating disorders that hold many "treats" for both clinicians and researchers. For example, the IFEs pose many of the most interesting questions central to epileptology: how are functional brain networks involved in the manifestation of epilepsy? What are the shared mechanisms of comorbidity between epilepsy and neurodevelopmental disorders? How do focal EEG discharges impact cognitive functioning? What explains the age-related expression of these syndromes? Why are EEG discharges and seizures so tightly locked to slow-wave sleep? In the last few decades, the clinical symptomatology and the respective courses of many IFEs have been described, although they are still not widely appreciated beyond the specialist community. Most neurologists would recognise the core syndromes of IFE to comprise: benign epilepsy of childhood with centro-temporal spikes or Rolandic epilepsy (BECTS/RE); Panayiotopoulos syndrome; and the idiopathic occipital epilepsies (Gastaut and photosensitive types). The Landau-Kleffner syndrome and the related (idiopathic) epilepsy with continuous spikes and waves in sleep (CSWS or ESES) are also often included, both as a consequence of the shared morphology of the interictal discharges and their potential evolution from core syndromes, for example, CSWS from BECTS. Atypical benign focal epilepsy of childhood also has shared electro-clinical features warranting inclusion. In addition, a number of less well-defined syndromes of IFE have been proposed, including benign childhood seizures with affective symptoms, benign childhood epilepsy with parietal spikes, benign childhood seizures with frontal or midline spikes, and benign focal seizures of adolescence. The

  10. Laparoscopic Partial Hepatectomy of Focal Nodular Hyperplasia

    Directory of Open Access Journals (Sweden)

    Mayu Sakata

    2012-11-01

    Full Text Available Focal nodular hyperplasia is a benign liver lesion incidentally discovered with increasing frequency because of the proliferation of imaging studies. Radiographic characterization can diagnose this pathologic lesion and nonoperative therapy is the standard of care. However, surgical resection may be required for diagnostic reasons or symptomatic patients. Depending on the anatomic location of the lesion, biopsy and/or resection can be performed laparoscopically. We herein report the case of a 26-year-old Japanese woman with a hepatic tumor who required a medical examination. Her medical history was negative for alcohol abuse, oral contraceptive administration and trauma. Clinical examination showed no significant symptoms. Ultrasonography, computed tomography and magnetic resonance imaging showed a mass located in the left lateral segment of the liver with a diameter of about 40 mm. It was difficult to diagnose the tumor definitively from these imaging studies, so we performed laparoscopic partial hepatectomy with successive firing of endoscopic staplers. The histopathological diagnosis was focal nodular hyperplasia. Surgical procedures and postoperative course were uneventful and the patient was discharged from the hospital on postoperative day 5.

  11. CT scan findings in focal epilepsy

    International Nuclear Information System (INIS)

    Kobayashi, Eiki; Mihara, Tadahiro; Yamamoto, Kunimitsu; Yamashita, Kenji; Asakura, Tetsuhiko

    1980-01-01

    In 80 cases of focal epilepsy, excluding such cases as late onset after the age of 30 and traumatic or expansive lesions, the epileptogenic foci have been studied by comparing the CT findings with the seizure types and the EEG findings. The results were as follows: (1) Abnormal CT findings were observed in 36% of the patients. (2) These findings were classified into 4 large groups: localized cerebral atrophy, localized low density, localized high density with contrast enhancement and diffuse cerebral atrophy. (3) The incidence of CT abnormality was higher in the cases with continuous and localized EEG abnormality than in the cases with other types of EEG abnormality. In 48% of the cases, the location of the abnormal CT findings coincided with their EEG foci. (4) In the cases of temporal lobe epilepsy without abnormal CT images, the print-out data compared with the bilateral promised temporal regions, before and after contrast enhancement. The EMI-No. of the medial temporal focus increased more than that of the contralateral side in 3 cases out of 4 after contrast-media injection. (5) Moreover, for the purpose of comparing the CT findings on general seizures with those in focal seizures, we have studied 80 cases of general seizures. In the cases of the general seizures, abnormal CT findings were observed in only 16%. These abnormal findings were diffuse in 5 cases, localized in 6 cases, and combined in 3 cases. (author)

  12. The Sentinel-4 UVN focal plane assemblies

    Science.gov (United States)

    Hinger, Jürgen; Hohn, Rüdiger; Gebhardt, Eyk; Reichardt, Jörg

    2017-09-01

    The Sentinel-4 UVN Instrument is a dispersive imaging spectrometer covering the UV-VIS and the NIR wavelength. It is developed and built under an ESA contract by an industrial consortium led by Airbus Defence and Space. It will be accommodated on board of the MTG-S (Meteosat Third Generation - Sounder) satellite that will be placed in a geostationary orbit over Europe sampling data for generating two-dimensional maps of a number of atmospheric trace gases. The incoming light is dispersed by reflective gratings and detected by the two (UVVIS and NIR) CCDs mounted inside the focal plane assemblies. Both CCD detectors acquire spectral channels and spatial sampling in two orthogonal directions and will be operated at about 215 K mainly to minimize random telegraph signal effects and to reduce dark current. Stringent detector temperature as well as alignment stability requirements of less than +/-0.1 K per day respectively of less than 2 micrometers/2 arcseconds from ground to orbit are driving the FPA thermo-mechanical design. A specific FPA design feature is the redundant LED-calibration system for bad pixel detection as well as pixel gain and linearity monitoring. This paper reports on the design and qualification of the Focal Plane Assemblies with emphasis on thermo-mechanical as well as alignment stability verification.

  13. The Sentinel 4 focal plane subsystem

    Science.gov (United States)

    Hohn, Rüdiger; Skegg, Michael P.; Hermsen, Markus; Hinger, Jürgen; Williges, Christian; Reulke, Ralf

    2017-09-01

    The Sentinel 4 instrument is an imaging spectrometer, developed by Airbus under ESA contract in the frame of the joint European Union (EU)/ESA COPERNICUS program with the objective of monitoring trace gas concentrations. Sentinel 4 will provide accurate measurements of key atmospheric constituents such as ozone, nitrogen dioxide, sulfur dioxide, formaldehyde, as well as aerosol and cloud properties. Sentinel 4 is unique in being the first geostationary UVN mission. The SENTINEL 4 space segment will be integrated on EUMETSAT's Meteosat Third Generation Sounder satellite (MTG-S). Sentinel 4 will provide coverage of Europe and adjacent regions. The Sentinel 4 instrument comprises as a major element two Focal Plane Subsystems (FPS) covering the wavelength ranges 305 nm to 500 nm (UVVIS) and 750 nm to 775 nm (NIR) respectively. The paper describes the Focal Plane Subsystems, comprising the detectors, the optical bench and the control electronics. Further the design and development approach will be presented as well as first measurement results of FPS Qualification Model.

  14. Focal CT abnormality and epileptogenic focus

    International Nuclear Information System (INIS)

    Yagi, Kazuichi; Mihara, Tadahiro; Tottori, Takayasu; Matsuda, Kazumi; Watanabe, Yutaka; Seino, Masakazu

    1989-01-01

    In 31 patients with temporal lobe epilepsy, the precise site of epileptogenic focus was determined by means of a depth EEG recording as one of the presurgical evaluations. In 13 patients, a CT scan revealed focal lesions; 7 in the left temporal lobe and 6 in the right temporal lobe. In 5 of the 7 patients and in 5 of the 6 patients the epileptogenic foci were determined in the temporal lobe on the side of a CT lesion. However, in 2 of the patients with a CT lesion in the left temporal lobe, independent epileptogenic foci were found in both the temporal lobes, and in the other patient with a CT lesion in the right temporal lobe, they were found in the right frontal and left temporal lobes. Thus, the CT lesions agreed in lateralization and focality with the epileptogenic foci in 10 of the 13 patients (77%), but they disagreed in 3 (23%). A CT lesion disclosed in the temporal lobe does not necessarily indicate the side and/or site where the epileptogenic focus may be localized. Although exceptions may be made, spatial disagreement was exemplified between the CT lesion and epileptogenic focus. Therefore, extreme caution has to be taken on the side and/or site of the epileptogenic focus when functional surgical indication is to be made. (author)

  15. Serial neuroradiological studies in focal cerebritis

    International Nuclear Information System (INIS)

    Hatta, S.; Mochizuki, H.; Kuru, Y.; Miwa, H.; Kondo, T.; Mori, H.; Mizuno, Y.

    1994-01-01

    We report serial neuroradiological studies in a patient with focal cerebritis in the head of the left caudate nucleus. On the day after the onset of symptoms, CT showed an ill-defined low density lesion. The lack of contrast enhancement appeared to be the most important finding for differentiating focal cerebritis from an encapsulated brain abscess or a tumour. MRI two days later revealed the centre of the lesion to be of slightly low intensity on T1-weighted inversion recovery (IR) images and very low intensity on T2-weighted spin echo images, which appeared to correspond to the early cerebritis stage of experimentally induced cerebritis and brain abscess. Ten days after the onset of symptoms, CT revealed a thin ring of enhancement in the head of the caudate nucleus, and a similar small ring was seen in the hypothalamus 16 days after the onset, corresponding to the late cerebritis stage. MRI nine days later revealed ill-defined high signal lesions within the involved area on the T1-weighted IR images. To our knowledge, this is the first published MRI documentation of the early cerebritis stage developing into an encapsulated brain abscess. The mechanisms underlying of these radiographic changes are discussed. (orig.)

  16. Structural and effective connectivity in focal epilepsy

    Directory of Open Access Journals (Sweden)

    Christopher S. Parker

    2018-01-01

    Full Text Available Patients with medically-refractory focal epilepsy may be candidates for neurosurgery and some may require placement of intracranial EEG electrodes to localise seizure onset. Assessing cerebral responses to single pulse electrical stimulation (SPES may give diagnostically useful data. SPES produces cortico-cortical evoked potentials (CCEPs, which infer effective brain connectivity. Diffusion-weighted images and tractography may be used to estimate structural brain connectivity. This combination provides the opportunity to observe seizure onset and its propagation throughout the brain, spreading contiguously along the cortex explored with electrodes, or non-contiguously. We analysed CCEPs and diffusion tractography in seven focal epilepsy patients and reconstructed the effective and structural brain networks. We aimed to assess the inter-modal similarity of the networks at a large scale across the cortex, the effective and structural connectivity of the ictal-onset zone, and investigate potential mechanisms of non-contiguous seizure spread. We found a significant overlap between structural and effective networks. Effective network CCEP amplitude, baseline variation, and outward connectivity was higher at ictal-onset zones, while structural connection strength within the ictal-onset zone tended to be higher. These findings support the concept of hyperexcitable cortex being associated with seizure generation. The high prevalence of structural and effective connections from the ictal-onset zone to sites of non-contiguous spread suggests that macroscopic structural and effective connections are plausible routes for non-contiguous seizure spread.

  17. Ultrasound elastographic techniques in focal liver lesions.

    Science.gov (United States)

    Conti, Clara Benedetta; Cavalcoli, Federica; Fraquelli, Mirella; Conte, Dario; Massironi, Sara

    2016-03-07

    Elastographic techniques are new ultrasound-based imaging techniques developed to estimate tissue deformability/stiffness. Several ultrasound elastographic approaches have been developed, such as static elastography, transient elastography and acoustic radiation force imaging methods, which include point shear wave and shear wave imaging elastography. The application of these methods in clinical practice aims at estimating the mechanical tissues properties. One of the main settings for the application of these tools has been liver stiffness assessment in chronic liver disease, which has been studied mainly using transient elastography. Another field of application for these techniques is the assessment of focal lesions, detected by ultrasound in organs such as pancreas, prostate, breast, thyroid, lymph nodes. Considering the frequency and importance of the detection of focal liver lesions through routine ultrasound, some studies have also aimed to assess the role that elestography can play in studying the stiffness of different types of liver lesions, in order to predict their nature and thus offer valuable non-invasive methods for the diagnosis of liver masses.

  18. Focal fatty infiltra- tion and focal fatty sparing of the liver

    African Journals Online (AJOL)

    Enrique

    Department of Radiology. Nelson Mandela School of Health Sciences. Durban. Fig. 1a. Unenhanced CT of the liver in case 1 demonstrates multiple focal low density regions in both lobes of the liver. Region of interest 1 over the fatty left lobe measured 10 HU while region of interest 2 over the right lobe measure 40 HU in.

  19. CT appearance of focal fatty infiltration of the liver

    International Nuclear Information System (INIS)

    Halvorsen, R.A.; Korobkin, M.; Ram, P.C.; Thompson, W.M.

    1982-01-01

    Focal fatty infiltration of the liver is an entity that may be confused with liver metastasis on computed tomography (CT). The imaging results and medical records of 16 patients with CT appearance suggestive of focal fatty liver were reviewed, three of whom had the simultaneous presence of metastitic liver disease. Focal fatty liver often has a distinctive appearance with CT, usually with a nonspherical shape, absence of mass effect, and density close to water. Liver metastases are usually round or oval, and unless cystic or necrotic, they have CT attenuation values closer to normal liver parenchyma than water. A radionuclide liver scan almost always resolves any confusion about the differential diagnosis of focal fatty liver: a well defined focus of photon deficiency is due to neoplasm rather than focal fatty infiltration. Sonography sometimes helps to confirm the CT impression, but may be misleading if the diagnosis of focal or diffuse fatty infiltration is not suspected before the examination

  20. The study of the focal trough in panoramic radiograph

    International Nuclear Information System (INIS)

    Park, C. S.; Kim, H. P.

    1982-01-01

    In the study of the focal trough of panoramic radiograph, using the Moritta company Panex EC a series of 48 exposures were taken with the 6-18 brass pins placed in the holes of the plastic model plate, then evaluated by 4 observers. The author analyzed the focal trough defined by the sharpness criteria and calculated the vertical and horizontal magnification range in the corrected focal trough. The results were as follows; 1. Continuous focal trough was not defined in the anterior region using a very high degree of sharpness. 2. As degree of sharpness used in the analysis became less, focal trough was continuous in the anterior and posterior regions, symmetrized bilaterally, and the widths of the focal trough increased more in the posterior region. 3. As sharpness criteria were reduced, the percentage range of image magnification increased in both vertical and horizontal magnification, and especially the percentage range of horizontal magnification was greater than that of vertical magnification.

  1. Multi-focal Vision and Gaze Control Improve Navigation Performance

    Directory of Open Access Journals (Sweden)

    Kolja Kuehnlenz

    2008-11-01

    Full Text Available Multi-focal vision systems comprise cameras with various fields of view and measurement accuracies. This article presents a multi-focal approach to localization and mapping of mobile robots with active vision. An implementation of the novel concept is done considering a humanoid robot navigation scenario where the robot is visually guided through a structured environment with several landmarks. Various embodiments of multi-focal vision systems are investigated and the impact on navigation performance is evaluated in comparison to a conventional mono-focal stereo set-up. The comparative studies clearly show the benefits of multi-focal vision for mobile robot navigation: flexibility to assign the different available sensors optimally in each situation, enhancement of the visible field, higher localization accuracy, and, thus, better task performance, i.e. path following behavior of the mobile robot. It is shown that multi-focal vision may strongly improve navigation performance.

  2. Focal cemento-osseous dysplasia of mandible.

    Science.gov (United States)

    Cankaya, Abdülkadir Burak; Erdem, Mehmet Ali; Olgac, Vakur; Firat, Deniz Refia

    2012-09-03

    Fibro-osseous lesions are disturbances in bone metabolism in which normal bone is replaced by a connective tissue matrix that then gradually develops into cemento-osseous tissue. Typically, the lesion is asymptomatic and is detected on routine radiographic examination. Radiologically, this lesion has three stages of maturation: pure radiolucent, radiopaque/mixed radiolucent, and radiopaque appearance. During these stages the lesion can be misdiagnosed. In this case report a 69-year- old patient with a a complaint of painless swelling of the left mandibular molar and premolar area is presented along with a review of the differential diagnoses considered in order to reach a final diagnosis of focal cemento-osseous dysplasia.

  3. Strong reducing of the laser focal volume

    CSIR Research Space (South Africa)

    Godin, T

    2011-08-01

    Full Text Available equal to -1 or +1 modeled on the p light rings of the incident TEMp0 beam. The transformation quality of a 30TEM beam into a single-lobed pattern in the focal plane is shown in Fig. 3. It is clear that the intensity pattern of the rectified beam... DOE (blue solid line), rectified 30TEM (red solid line) -3 -2 -1 0 1 2 3 0 1 2 3 4 z=0 z=f DOE Fig. 2 -60 -50 -40 -30 -20 -10 0 10 20 30 40 50 60 0,0 0,2 0,4 0,6 0,8 1,0 TEM30 without DOE "rectified" TEM30 TEM00 In te ns...

  4. Smart trigger logic for focal plane arrays

    Science.gov (United States)

    Levy, James E; Campbell, David V; Holmes, Michael L; Lovejoy, Robert; Wojciechowski, Kenneth; Kay, Randolph R; Cavanaugh, William S; Gurrieri, Thomas M

    2014-03-25

    An electronic device includes a memory configured to receive data representing light intensity values from pixels in a focal plane array and a processor that analyzes the received data to determine which light values correspond to triggered pixels, where the triggered pixels are those pixels that meet a predefined set of criteria, and determines, for each triggered pixel, a set of neighbor pixels for which light intensity values are to be stored. The electronic device also includes a buffer that temporarily stores light intensity values for at least one previously processed row of pixels, so that when a triggered pixel is identified in a current row, light intensity values for the neighbor pixels in the previously processed row and for the triggered pixel are persistently stored, as well as a data transmitter that transmits the persistently stored light intensity values for the triggered and neighbor pixels to a data receiver.

  5. Pharmacological response of systemically derived focal epileptic lesions

    Energy Technology Data Exchange (ETDEWEB)

    Remler, M.P.; Sigvardt, K.; Marcussen, W.H.

    1986-11-01

    Focal epileptic lesions were made in rats by systemic focal epileptogenesis. In this method, a focal lesion of the blood-brain barrier (BBB) is produced by focal alpha irradiation followed by repeated systemic injection of a convulsant drug that cannot cross the normal BBB, resulting in a chronic epileptic focus. Changes in the spike frequency of these foci in response to various drugs was recorded. The controls, saline and chlorpromazine, produced no change. Phenytoin, phenobarbital, chlordiazepoxide, and valproic acid produced the expected decrease in spike frequency. Pentobarbital and diazepam produced a paradoxical increase in spike frequency.

  6. Focal cryotherapy: step by step technique description

    Directory of Open Access Journals (Sweden)

    Cristina Redondo

    Full Text Available ABSTRACT Introduction and objective: Focal cryotherapy emerged as an efficient option to treat favorable and localized prostate cancer (PCa. The purpose of this video is to describe the procedure step by step. Materials and methods: We present the case of a 68 year-old man with localized PCa in the anterior aspect of the prostate. Results: The procedure is performed under general anesthesia, with the patient in lithotomy position. Briefly, the equipment utilized includes the cryotherapy console coupled with an ultrasound system, argon and helium gas bottles, cryoprobes, temperature probes and an urethral warming catheter. The procedure starts with a real-time trans-rectal prostate ultrasound, which is used to outline the prostate, the urethra and the rectal wall. The cryoprobes are pretested and placed in to the prostate through the perineum, following a grid template, along with the temperature sensors under ultrasound guidance. A cystoscopy confirms the right positioning of the needles and the urethral warming catheter is installed. Thereafter, the freeze sequence with argon gas is started, achieving extremely low temperatures (-40°C to induce tumor cell lysis. Sequentially, the thawing cycle is performed using helium gas. This process is repeated one time. Results among several series showed a biochemical disease-free survival between 71-93% at 9-70 month- follow-up, incontinence rates between 0-3.6% and erectile dysfunction between 0-42% (1–5. Conclusions: Focal cryotherapy is a feasible procedure to treat anterior PCa that may offer minimal morbidity, allowing good cancer control and better functional outcomes when compared to whole-gland treatment.

  7. Sighting optics including an optical element having a first focal length and a second focal length and methods for sighting

    Science.gov (United States)

    Crandall, David Lynn

    2011-08-16

    Sighting optics include a front sight and a rear sight positioned in a spaced-apart relation. The rear sight includes an optical element having a first focal length and a second focal length. The first focal length is selected so that it is about equal to a distance separating the optical element and the front sight and the second focal length is selected so that it is about equal to a target distance. The optical element thus brings into simultaneous focus for a user images of the front sight and the target.

  8. Seismogeodesy of the 2014 Mw6.1 Napa earthquake, California: Rapid response and modeling of fast rupture on a dipping strike-slip fault

    Science.gov (United States)

    Melgar, Diego; Geng, Jianghui; Crowell, Brendan W.; Haase, Jennifer S.; Bock, Yehuda; Hammond, William C.; Allen, Richard M.

    2015-07-01

    Real-time high-rate geodetic data have been shown to be useful for rapid earthquake response systems during medium to large events. The 2014 Mw6.1 Napa, California earthquake is important because it provides an opportunity to study an event at the lower threshold of what can be detected with GPS. We show the results of GPS-only earthquake source products such as peak ground displacement magnitude scaling, centroid moment tensor (CMT) solution, and static slip inversion. We also highlight the retrospective real-time combination of GPS and strong motion data to produce seismogeodetic waveforms that have higher precision and longer period information than GPS-only or seismic-only measurements of ground motion. We show their utility for rapid kinematic slip inversion and conclude that it would have been possible, with current real-time infrastructure, to determine the basic features of the earthquake source. We supplement the analysis with strong motion data collected close to the source to obtain an improved postevent image of the source process. The model reveals unilateral fast propagation of slip to the north of the hypocenter with a delayed onset of shallow slip. The source model suggests that the multiple strands of observed surface rupture are controlled by the shallow soft sediments of Napa Valley and do not necessarily represent the intersection of the main faulting surface and the free surface. We conclude that the main dislocation plane is westward dipping and should intersect the surface to the east, either where the easternmost strand of surface rupture is observed or at the location where the West Napa fault has been mapped in the past.

  9. Mesozoic strike-slip movement of the Dunhua-Mishan Fault Zone in NE China: A response to oceanic plate subduction

    Science.gov (United States)

    Liu, Cheng; Zhu, Guang; Zhang, Shuai; Gu, Chengchuan; Li, Yunjian; Su, Nan; Xiao, Shiye

    2018-01-01

    The NE-striking Dunhua-Mishan Fault Zone (DMFZ) is one of two branches of the continental-scale sinistral Tan-Lu Fault Zone in NE China. The field data presented here indicate that the ca. 1000 km long DMFZ records two phases of sinistral faulting. The structures produced by these two phases of faulting include NE-SW-striking ductile shear belts and brittle faults, respectively. Mylonite-hosted microstructures and quartz c-axis fabrics suggest deformation temperatures of 450 °C-500 °C for the ductile shear belts. Combining new zircon U-Pb dates for 14 igneous rock samples analyzed during this study with the geology of this region indicates these shear belts formed during the earliest Early Cretaceous. This phase of sinistral displacement represents the initial formation of the DMFZ in response to the northward propagation of the Tan-Lu Fault Zone into NE China. A phase of Early Cretaceous rifting was followed by a second phase of sinistral faulting at 102-96 Ma, as evidenced by our new U-Pb ages for associated igneous rocks. Combining our new data with the results of previous research indicates that the DFMZ records a four-stage Cretaceous evolutionary history, where initial sinistral faulting at the beginning of the Early Cretaceous gave way to rifting during the rest of the Early Cretaceous. This was followed by a second phase of sinistral faulting at the beginning of the Late Cretaceous and a second phase of local rifting during the rest of the Late Cretaceous. The Cretaceous evolution of the DMFZ records the synchronous tectonic evolution of the NE China continent bordering the Pacific Ocean. Two phases of regional N-S compression generated the two phases of sinistral faulting within the DMFZ, whereas two-stage regional extension generated the two phases of rifting. The two compressive events were the result of the rapid low-angle subduction of the Izanagi and Pacific plates, whereas the two-stage extension was caused by the roll-back of these respective plates. The final closure of the Mongol-Okhotsk Ocean at the beginning of the Early Cretaceous intensified the synchronous compression in NE China, causing the northward propagation of the Tan-Lu Fault Zone.

  10. SHRIMP U-Pb zircon dating of Archean core complex formatio and pancratonic strike-slip deformation in the East Pilbara Granite-Greenstone Terrain

    NARCIS (Netherlands)

    Zegers, T.E.; Nelson, D.R.; Wijbrans, J.R.; White, S.H.

    2001-01-01

    Sensitive high-resolution ion microprobe (SHRIMP) U-Pb dating of zircons from granitic rocks in the East Pilbara Granite-Greenstone Terrain has provided time constraints for main tectonic events in the Shaw Granitoid Complex and has shown that deformation was intricately related to granitoid

  11. Empirical Relationships Among Magnitude and Surface Rupture Characteristics of Strike-Slip Faults: Effect of Fault (System) Geometry and Observation Location, Dervided From Numerical Modeling

    Science.gov (United States)

    Zielke, O.; Arrowsmith, J.

    2007-12-01

    In order to determine the magnitude of pre-historic earthquakes, surface rupture length, average and maximum surface displacement are utilized, assuming that an earthquake of a specific size will cause surface features of correlated size. The well known Wells and Coppersmith (1994) paper and other studies defined empirical relationships between these and other parameters, based on historic events with independently known magnitude and rupture characteristics. However, these relationships show relatively large standard deviations and they are based only on a small number of events. To improve these first-order empirical relationships, the observation location relative to the rupture extent within the regional tectonic framework should be accounted for. This however cannot be done based on natural seismicity because of the limited size of datasets on large earthquakes. We have developed the numerical model FIMozFric, based on derivations by Okada (1992) to create synthetic seismic records for a given fault or fault system under the influence of either slip- or stress boundary conditions. Our model features A) the introduction of an upper and lower aseismic zone, B) a simple Coulomb friction law, C) bulk parameters simulating fault heterogeneity, and D) a fault interaction algorithm handling the large number of fault patches (typically 5,000-10,000). The joint implementation of these features produces well behaved synthetic seismic catalogs and realistic relationships among magnitude and surface rupture characteristics which are well within the error of the results by Wells and Coppersmith (1994). Furthermore, we use the synthetic seismic records to show that the relationships between magntiude and rupture characteristics are a function of the observation location within the regional tectonic framework. The model presented here can to provide paleoseismologists with a tool to improve magnitude estimates from surface rupture characteristics, by incorporating the regional and local structural context which can be determined in the field: Assuming a paleoseismologist measures the offset along a fault caused by an earthquake, our model can be used to determine the probability distribution of magnitudes which are capable of producing the observed offset, accounting for regional tectonic setting and observation location.

  12. Geomorphic Evidence of a Complex late-Cenozoic Uplift and Lateral Displacement History Along the 2013 M7.7 Baluchistan, Pakistan Strike-slip Rupture

    Science.gov (United States)

    Harbor, D. J.; Barnhart, W. D.

    2017-12-01

    The 2013 M7.7 Baluchistan earthquake in southern Pakistan ruptured 200 km of the north-dipping Hoshab reverse fault with dominantly lateral motion, clearly at odds with the regional topography created by previous reverse fault offsets. The kinematics of this earthquake led to the hypotheses that the Hoshab fault may alternatively slip in a reverse and lateral sense (bi-modal slip), and that the southeast Makran rotates as a uniform block around the fault (ball-and-socket rotation). Here, we use river profiles, regional relief, fault locations, and detailed geomorphic maps derived from optical imagery and DEMs to evaluate the recent uplift history of this region. We find that late Cenozoic fault zone geomorphology supports a spatially complex transition from lateral-dominated offsets in the NE to reverse-dominated offsets in the SW. Additionally, fault zone geomorphology suggests that the location of the Hoshab fault itself may change through time, leading to active incision of footwall alluvial fans and pediments. Stream profiles likewise record incision patterns that vary along the Hoshab fault. Incision and deposition in the SW are illustrative of relative footwall subsidence, consistent with recent uplift on the Hoshab fault; whereas incision and deposition in the NE are illustrative of relative footwall uplift consistent with ongoing regional uplift due to ball-and-socket rotations and dominantly lateral offsets along the northern Hoshab fault. The largest streams also record multiple, discrete, base-level drops, including the presence of convex-up river profiles in the hanging wall of the Hoshab fault. These profiles along hanging wall streams highlight a complex spatial and temporal history of reverse offset, lateral channel offset, and base-level resetting in regional streams that are altogether inconsistent with the kinematics of the 2013 earthquake alone, but that are consistent with the bi-modal slip model. Additionally, the evidence of footwall uplift in the NE is consistent with regional uplift due to ball-and-socket rotations superimposed on the Hoshab fault. These results indicate that the styles of fault slip in the Makran change in time and space in response to ongoing convergence and block rotations despite negligible uplift during the 2013 earthquake.

  13. Breaching of strike-slip faults and flooding of pull-apart basins to form the southern Gulf of California seaway from 8 to 6 Ma

    Science.gov (United States)

    Umhoefer, P. J.; Skinner, L. A.; Oskin, M. E.; Dorsey, R. J.; Bennett, S. E. K.; Darin, M. H.

    2017-12-01

    Studies from multiple disciplines delineate the development of the oblique-divergent Pacific - North America plate boundary in the southern Gulf of California. Integration of onshore data from the Loreto - Santa Rosalia margin with offshore data from the Pescadero, Farallon, and Guaymas basins provides a detailed geologic history. Our GIS-based paleotectonic maps of the plate boundary from 9 to 6 Ma show that evolution of pull-apart basins led to the episodic northwestward encroachment of the Gulf of California seaway. Because adjacent pull-apart basins commonly have highlands between them, juxtaposition of adjacent basin lows during translation and pull apart lengthening played a critical role in seaway flooding. Microfossils and volcanic units date the earliest marine deposits at 9(?) - 8 Ma at the mouth of the Gulf. By ca. 8 Ma, the seaway had flooded north to the Pescadero basin, while the Loreto fault and the related fault-termination basin was proposed to have formed along strike at the plate margin. East of Loreto basin, a short topographic barrier between the Pescadero and Farallon pull-apart basins suggests that the Farallon basin was either a terrestrial basin, or if breaching occurred, it may contain 8 Ma salt or marine deposits. This early southern seaway formed along a series of pull-apart basins within a narrow belt of transtension structurally similar to the modern Walker Lane in NV and CA. At ca. 7 Ma, a series of marine incursions breached a 75-100 km long transtensional fault barrier between the Farallon and Guaymas basins offshore Bahía Concepción. Repeated breaching events and the isolation of the Guaymas basin in a subtropical setting formed a 2 km-thick salt deposit imaged in offshore seismic data, and thin evaporite deposits in the onshore Santa Rosalia basin. Lengthening of the Guaymas, Yaqui, and Tiburon basins caused breaches of the intervening Guaymas and Tiburón transforms by 6.5-6.3 Ma, forming a permanent 1500 km-long marine seaway up to the Salton Trough. By 6 Ma, the Guaymas basin had uniquely evolved to oceanic seafloor spreading, while the marine seaway to the south remained a series of pull-apart and transtensional basins with seafloor spreading delayed until 3 - 2 Ma. There is evidence of rift flank uplift near the Loreto fault/basin in this 6 - 3 Ma transitional period.

  14. Structural evolution of Cenozoic basins in northeastern Tunisia, in response to sinistral strike-slip movement on the El Alia-Teboursouk Fault

    Science.gov (United States)

    Bejaoui, Hamida; Aïfa, Tahar; Melki, Fetheddine; Zargouni, Fouad

    2017-10-01

    This paper resolves the structural complexity of Cenozoic sedimentary basins in northeastern Tunisia. These basins trend NE-SW to ∼ E-W, and are bordered by old fracture networks. Detailed descriptions of the structural features in outcrop and in subsurface data suggest that the El Alia-Teboursouk Fault zone in the Bizerte area evolved through a series of tectonic events. Cross sections, lithostratigraphic correlations, and interpretation of seismic profiles through the basins show evidence for: (i) a Triassic until Jurassic-Early Cretaceous rifting phase that induced lateral variations of facies and strata thicknesses; (ii) a set of faults oriented NE-SW, NW-SE, N-S, and E-W that guided sediment accumulation in pull-apart basins, which were subject to compressive and transpressive deformation during Eocene (Lutetian-Priabonian), Miocene (Tortonian), and Pliocene-Quaternary; and (iii) NNW-SSE to NS contractional events that occurred during the Late Pliocene. Part of the latest phase has been the formation of different synsedimentary folded structures with significant subsidence inversion. Such events have been responsible for the reactivation of inherited faults, and the intrusion of Triassic evaporites, ensuring the role of a slip layer. The combined effects of the different paleoconstraints and halokinetic movements are at the origin of the evolution of these pull-apart basins. The subsurface data suggest that an important fault displacement occurred during the Mesozoic-Cenozoic. The patterns of sediment accumulation in the different basins reflect a high activity of deep ancient faults.

  15. Vertical-axis rotations and deformation along the active strike-slip El Tigre Fault (Precordillera of San Juan, Argentina) assessed through palaeomagnetism and anisotropy of magnetic susceptibility

    Science.gov (United States)

    Fazzito, Sabrina Y.; Rapalini, Augusto E.; Cortés, José M.; Terrizzano, Carla M.

    2017-03-01

    Palaeomagnetic data from poorly consolidated to non-consolidated late Cenozoic sediments along the central segment of the active El Tigre Fault (Central-Western Precordillera of the San Juan Province, Argentina) demonstrate broad cumulative deformation up to 450 m from the fault trace and reveal clockwise and anticlockwise vertical-axis rotations of variable magnitude. This deformation has affected in different amounts Miocene to late Pleistocene samples and indicates a complex kinematic pattern. Several inherited linear structures in the shear zone that are oblique to the El Tigre Fault may have acted as block boundary faults. Displacement along these faults may have resulted in a complex pattern of rotations. The maximum magnitude of rotation is a function of the age of the sediments sampled, with largest values corresponding to middle Miocene-lower Pliocene deposits and minimum values obtained from late Pleistocene deposits. The kinematic study is complemented by low-field anisotropy of magnetic susceptibility data to show that the local strain regime suggests a N-S stretching direction, subparallel to the strike of the main fault.

  16. Pleistocene Brawley and Ocotillo Formations: Evidence for initial strike-slip deformation along the San Felipe and San Jacinto fault zonez, Southern California

    Science.gov (United States)

    Kirby, S.M.; Janecke, S.U.; Dorsey, R.J.; Housen, B.A.; Langenheim, V.E.; McDougall, K.A.; Steeley, A.N.

    2007-01-01

    We examine the Pleistocene tectonic reorganization of the Pacific-North American plate boundary in the Salton Trough of southern California with an integrated approach that includes basin analysis, magnetostratigraphy, and geologic mapping of upper Pliocene to Pleistocene sedimentary rocks in the San Felipe Hills. These deposits preserve the earliest sedimentary record of movement on the San Felipe and San Jacinto fault zones that replaced and deactivated the late Cenozoic West Salton detachment fault. Sandstone and mudstone of the Brawley Formation accumulated between ???1.1 and ???0.6-0.5 Ma in a delta on the margin of an arid Pleistocene lake, which received sediment from alluvial fans of the Ocotillo Formation to the west-southwest. Our analysis indicates that the Ocotillo and Brawley formations prograded abruptly to the east-northeast across a former mud-dominated perennial lake (Borrego Formation) at ???1.1 Ma in response to initiation of the dextral-oblique San Felipe fault zone. The ???25-km-long San Felipe anticline initiated at about the same time and produced an intrabasinal basement-cored high within the San Felipe-Borrego basin that is recorded by progressive unconformities on its north and south limbs. A disconformity at the base of the Brawley Formation in the eastern San Felipe Hills probably records initiation and early blind slip at the southeast tip of the Clark strand of the San Jacinto fault zone. Our data are consistent with abrupt and nearly synchronous inception of the San Jacinto and San Felipe fault zones southwest of the southern San Andreas fault in the early Pleistocene during a pronounced southwestward broadening of the San Andreas fault zone. The current contractional geometry of the San Jacinto fault zone developed after ???0.5-0.6 Ma during a second, less significant change in structural style. ?? 2007 by The University of Chicago. All rights reserved.

  17. Geochemistry of travertine deposits in the Eastern Anatolia District: an example of the Karakoçan-Yoğunağaç (Elazığ) and Mazgirt-Dedebağ (Tunceli) travertines, Turkey

    OpenAIRE

    KALENDER, LEYLA; OKAN, ÖZLEM ÖZTEKİN; İNCEÖZ, MURAT; ÇETİNDAĞ, BAHATTİN; YILDIRIM, VESİLE

    2015-01-01

    The Karakoçan-Yoğunağaç (Elazığ) and Mazgirt-Dedebağ (Tunceli) travertines, which are related to thermal springs, are situated on the right-lateral strike-slip Karakoçan Fault Zone (KFZ) and left-lateral strike-slip Pamuklu Fault Zone (PFZ) in eastern Anatolia. The surface area of the travertines varies from m2 to km2. Morphologically, the travertines are classified as ridge, banded, and terrace types due to deposition in different ways, in the releasing/restraining bends of the KFZ and PFZ a...

  18. Radiologic manifestations of focal cerebral hyperemia in acute stroke

    DEFF Research Database (Denmark)

    Olsen, Tom Skyhøj; Skriver, E B; Herning, M

    1991-01-01

    In 16 acute stroke patients with focal cerebral hyperemia angiography and regional cerebral blood flow (rCBF) were studied 1 to 4 days post stroke. CT was performed twice with and without contrast enhancement 3 +/- 1 days and 16 +/- 4 days post stroke. Angiographic evidence of focal cerebral hype...

  19. Focal decompositions for linear differential equations of the second order

    Directory of Open Access Journals (Sweden)

    L. Birbrair

    2003-01-01

    two-points problems to itself such that the image of the focal decomposition associated to the first equation is a focal decomposition associated to the second one. In this paper, we present a complete classification for linear second-order equations with respect to this equivalence relation.

  20. Focal necrotizing pneumonia is a distinct entity from lung abscess.

    Science.gov (United States)

    Seo, Hyewon; Cha, Seung-Ick; Shin, Kyung-Min; Lim, Jaekwang; Yoo, Seung-Soo; Lee, Jaehee; Lee, Shin-Yup; Kim, Chang-Ho; Park, Jae-Yong

    2013-10-01

    'Focal necrotizing pneumonia' was defined as a localized type of necrotizing pneumonia characterized by a single or few cavities of low density without rim enhancement on computed tomography (CT) scan. The purpose of this study was to investigate the clinical features and course of patients with focal necrotizing pneumonia, thereby elucidating its clinical relevance. The present study was conducted retrospectively in patients who had been interpreted as having lung abscess or necrotizing pneumonia on CT scan. Clinical and radiological characteristics were compared between the focal necrotizing pneumonia and lung abscess groups. Overall, 68 patients with focal necrotizing pneumonia (n = 35) or lung abscess (n = 33) were included in the present study. The frequency of risk factors for aspiration was significantly lower in the focal necrotizing group, compared with the lung abscess group (14.3% vs 45.5%, P = 0.005). Compared with lung abscess, focal necrotizing pneumonia was observed more commonly in non-gravity-dependent segments (66% vs 36%, P lung abscess group (31% vs 12%, P = 0.08). However, in terms of treatment outcomes, a similar high rate of success was observed in both groups: 97%, respectively. Compared to lung abscess, focal necrotizing pneumonia occurs more commonly in non-gravity-dependent segments with lower incidence of risk factors for aspiration. Similar to lung abscess, the rate of success for treatment of focal necrotizing pneumonia was high. © 2013 The Authors. Respirology © 2013 Asian Pacific Society of Respirology.

  1. Proximal Focal Femoral Deficiency in Ibadan a Developing ...

    African Journals Online (AJOL)

    The cultural aversion to amputation in our environment makes it difficult to employ that option of treatment. Proximal focal femoral deficiency in Ibadan a developing country's perspective and a review of the literature. Keywords: Proximal focal femoral deficiency , congenital malformations , limb malformations , lower limb ...

  2. Concordance of MRI and EEG Focal Slowing in Nonsyndromic Epilepsy

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2013-04-01

    Full Text Available Investigators at the Kangwon National University, Korea, and The Epilepsy Center, Lurie Children’s Hospital of Chicago, USA studied the correlation and significance of EEG focal slowing and focal MRI abnormalities in 253 children with nonsyndromic epilepsy.

  3. An empirical assessment of the focal species hypothesis.

    Science.gov (United States)

    Lindenmayer, D B; Lane, P W; Westgate, M J; Crane, M; Michael, D; Okada, S; Barton, P S

    2014-12-01

    Biodiversity surrogates and indicators are commonly used in conservation management. The focal species approach (FSA) is one method for identifying biodiversity surrogates, and it is underpinned by the hypothesis that management aimed at a particular focal species will confer protection on co-occurring species. This concept has been the subject of much debate, in part because the validity of the FSA has not been subject to detailed empirical assessment of the extent to which a given focal species actually co-occurs with other species in an assemblage. To address this knowledge gap, we used large-scale, long-term data sets of temperate woodland birds to select focal species associated with threatening processes such as habitat isolation and loss of key vegetation attributes. We quantified co-occurrence patterns among focal species, species in the wider bird assemblage, and species of conservation concern. Some, but not all, focal species were associated with high levels of species richness. One of our selected focal species was negatively associated with the occurrence of other species (i.e., it was an antisurrogate)-a previously undescribed property of nominated focal species. Furthermore, combinations of focal species were not associated with substantially elevated levels of bird species richness, relative to levels associated with individual species. Our results suggest that although there is some merit to the underpinning concept of the FSA, there is also a need to ensure that actions are sufficiently flexible because management tightly focused on a given focal species may not benefit some other species, including species of conservation concern, such of which might not occur in species-rich assemblages. © 2014 Society for Conservation Biology.

  4. [Sotos syndrome associated with focal dystonia].

    Science.gov (United States)

    Bravo, M; Chacón, J; Bautista, E; Pérez-Camacho, I; Trujillo, A; Grande, M A

    Sotos syndrome is a form of infantile gigantism characterized by excessive body size from the time of birth, particular facies, acromegalic changes and signs of non-progressive cerebral involvement. The etiology is unknown. Diagnosis is based on somatometric data and the particular phenotype traits. Biochemical and endocrine studies are normal. Torticollis is a focal dystonia and therefore more common in adults. A 20 year old woman with macrosomic features since birth presented with: weight 104 kg, height 182 cm; prognathism, hypertelorism, a broad over hanging forehead with a high hair line; large ears, hands and feet; torticollis towards the right with elevation and anteroversion of the right shoulder which caused symptomatic scoliosis. She was bradypsychic and rather slow in speech. The complementary tests done (cerebral and cervical CT and MR, bone gammography, evoked potentials, EMG-ENG, sural nerve biopsy, biopsy of skin and muscle, EEG and hormone and biochemistry studies) were normal. The torticollis was treated with botulinus toxin and improved considerably, as did the scoliosis. To date, dystonia has not been described in association with Sotos syndrome. This may be a causal association, or even perhaps hereditary, since the patient's mother had dystonia (in the form of blepharospasm).

  5. Depression in focal, segmental and generalized dystonia.

    Science.gov (United States)

    Lewis, L; Butler, A; Jahanshahi, M

    2008-11-01

    Dystonia causes body disfigurement in the majority of those affected. Our aim was to test the hypothesis that low self-esteem resulting from the sense of disfigurement is an important component of self-reported depression in focal, segmental and generalized dystonia. Questionnaires to assess self-reported depression, self-esteem, body concept, disfigurement, disability and quality of life were completed by 329 community based dystonia patients. Moderate to severe depression was reported by 30 %. Self-reported depression had a strong somatic component, but patients also showed a specific concern with self-image. Extent of dystonia, body parts affected and marital status influenced self-reported depression in dystonia. Self esteem, body concept, disfigurement and quality of life emerged as factors which accounted for the variance of self-reported depression in dystonia. These results suggest that in dystonia, disfigurement, negative body concept, low self-esteem, and the impact of the disease on quality of life make important contributions to depression. However, longitudinal followup is required to firmly establish the direction of causality between depression and these psychosocial variables in dystonia.

  6. Visual agnosia and focal brain injury.

    Science.gov (United States)

    Martinaud, O

    Visual agnosia encompasses all disorders of visual recognition within a selective visual modality not due to an impairment of elementary visual processing or other cognitive deficit. Based on a sequential dichotomy between the perceptual and memory systems, two different categories of visual object agnosia are usually considered: 'apperceptive agnosia' and 'associative agnosia'. Impaired visual recognition within a single category of stimuli is also reported in: (i) visual object agnosia of the ventral pathway, such as prosopagnosia (for faces), pure alexia (for words), or topographagnosia (for landmarks); (ii) visual spatial agnosia of the dorsal pathway, such as cerebral akinetopsia (for movement), or orientation agnosia (for the placement of objects in space). Focal brain injuries provide a unique opportunity to better understand regional brain function, particularly with the use of effective statistical approaches such as voxel-based lesion-symptom mapping (VLSM). The aim of the present work was twofold: (i) to review the various agnosia categories according to the traditional visual dual-pathway model; and (ii) to better assess the anatomical network underlying visual recognition through lesion-mapping studies correlating neuroanatomical and clinical outcomes. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  7. Nonhuman primate models of focal cerebral ischemia

    Directory of Open Access Journals (Sweden)

    Jingjing Fan

    2017-01-01

    Full Text Available Rodents have been widely used in the production of cerebral ischemia models. However, successful therapies have been proven on experimental rodent stroke model, and they have often failed to be effective when tested clinically. Therefore, nonhuman primates were recommended as the ideal alternatives, owing to their similarities with the human cerebrovascular system, brain metabolism, grey to white matter ratio and even their rich behavioral repertoire. The present review is a thorough summary of ten methods that establish nonhuman primate models of focal cerebral ischemia; electrocoagulation, endothelin-1-induced occlusion, microvascular clip occlusion, autologous blood clot embolization, balloon inflation, microcatheter embolization, coil embolization, surgical suture embolization, suture, and photochemical induction methods. This review addresses the advantages and disadvantages of each method, as well as precautions for each model, compared nonhuman primates with rodents, different species of nonhuman primates and different modeling methods. Finally it discusses various factors that need to be considered when modelling and the method of evaluation after modelling. These are critical for understanding their respective strengths and weaknesses and underlie the selection of the optimum model.

  8. Evaluation of Hemodynamics in Focal Steatosis and Focal Spared Lesion of the Liver Using Contrast-Enhanced Ultrasonography with Sonazoid

    International Nuclear Information System (INIS)

    Shiozawa, K.; Watanabe, M.; Ikehara, T.; Kogame, M.; Shinohara, M.; Shinohara, M.; Ishii, K.; Igarashi, Y.; Sumino, Y.; Shiozawa, K.; Makino, H.

    2014-01-01

    We aim to investigate the hemodynamics in focal steatosis and focal spared lesion of the liver using contrast-enhanced ultrasonography (CEUS) with Sonazoid. The subjects were 47 patients with focal steatosis and focal spared lesion. We evaluated enhancement patterns (hyper enhancement, iso enhancement, and hypo enhancement) in the vascular phase and the presence or absence of a hypoechoic area in the post vascular phase for these lesions using CEUS. Of the 24 patients with focal steatosis, the enhancement pattern was iso enhancement in 19 and hypo enhancement in 5. Hypoechoic areas were noted in the post vascular phase in 3 patients. Of the 23 patients with focal spared lesions, the enhancement pattern was iso enhancement in 18 and hyper enhancement in 5. No hypoechoic areas were noted in the post vascular phase in any patient. The hemodynamics in focal steatosis and focal spared lesions in non diffuse fatty liver can be observed using low-invasive procedures in real-time by CEUS. It was suggested that differences in the dynamics of enhancement in the vascular phase of CEUS were influenced by the fat deposits in the target lesion, the surrounding liver parenchyma, and the third inflow.

  9. Neotectonic inversion of the Hindu Kush-Pamir mountain region

    Science.gov (United States)

    Ruleman, C.A.

    2011-01-01

    The Hindu Kush-Pamir region of southern Asia is one of Earth's most rapidly deforming regions and it is poorly understood. This study develops a kinematic model based on active faulting in this part of the Trans-Himalayan orogenic belt. Previous studies have described north-verging thrust faults and some strike-slip faults, reflected in the northward-convex geomorphologic and structural grain of the Pamir Mountains. However, this structural analysis suggests that contemporary tectonics are changing the style of deformation from north-verging thrusts formed during the initial contraction of the Himalayan orogeny to south-verging thrusts and a series of northwest-trending, dextral strike-slip faults in the modern transpressional regime. These northwest-trending fault zones are linked to the major right-lateral Karakoram fault, located to the east, as synthetic, conjugate shears that form a right-stepping en echelon pattern. Northwest-trending lineaments with dextral displacements extend continuously westward across the Hindu Kush-Pamir region indicating a pattern of systematic shearing of multiple blocks to the northwest as the deformation effects from Indian plate collision expands to the north-northwest. Locally, east-northeast- and northwest-trending faults display sinistral and dextral displacement, respectively, yielding conjugate shear pairs developed in a northwest-southeast compressional stress field. Geodetic measurements and focal mechanisms from historical seismicity support these surficial, tectono-morphic observations. The conjugate shear pairs may be structurally linked subsidiary faults and co-seismically slip during single large magnitude (> M7) earthquakes that occur on major south-verging thrust faults. This kinematic model provides a potential context for prehistoric, historic, and future patterns of faulting and earthquakes.

  10. Focal Atrichia: A Diagnostic Clue in Female Pattern Hair Loss.

    Science.gov (United States)

    Olsen, Elise A; Whiting, David A

    2017-10-07

    Focal atrichia is a common clinical finding in female pattern hair loss whose specificity and histologic findings need further clarification. To determine the frequency of focal atrichia in various types of hair loss and its histologic characteristics in female pattern hair loss. Part 1: Review of 250 consecutive female patients seen with hair loss for the presence of focal atrichia and Part 2: paired biopsies of haired areas vs focal atrichia in 18 subjects with female pattern hair loss RESULTS: Focal atrichia was seen in 46/104 (44%) of women with female pattern hair loss, including 67% of late onset vs 15% of early onset, compared to 3/146 (2%) of those with other hair disorders Biopsy findings of focal atrichia in female pattern hair loss showed primarily a more progressive miniaturization process than that of haired areas of the scalp. Some women with female pattern hair loss may have had concomitant chronic telogen effluvium CONCLUSIONS: When present, focal atrichia is a clinical clue to the diagnosis of female pattern hair loss, particularly late onset subtype. Copyright © 2017. Published by Elsevier Inc.

  11. The semiology of febrile seizures: Focal features are frequent.

    Science.gov (United States)

    Takasu, Michihiko; Kubota, Tetsuo; Tsuji, Takeshi; Kurahashi, Hirokazu; Numoto, Shingo; Watanabe, Kazuyoshi; Okumura, Akihisa

    2017-08-01

    To clarify the semiology of febrile seizures (FS) and to determine the frequency of FS with symptoms suggestive of focal onset. FS symptoms in children were reported within 24h of seizure onset by the parents using a structured questionnaire consisting principally of closed-ended questions. We focused on events at seizure commencement, including changes in behavior and facial expression, and ocular and oral symptoms. We also investigated the autonomic and motor symptoms developing during seizures. The presence or absence of focal and limbic features was determined for each patient. The associations of certain focal and limbic features with patient characteristics were assessed. Information was obtained on FS in 106 children. Various events were recorded at seizure commencement. Behavioral changes were observed in 35 children, changes in facial expression in 53, ocular symptoms in 78, and oral symptoms in 90. In terms of events during seizures, autonomic symptoms were recognized in 78, and convulsive motor symptoms were recognized in 68 children. Focal features were evident in 81 children; 38 children had two or more such features. Limbic features were observed in 44 children, 9 of whom had two or more such features. There was no significant relationship between any patient characteristic and the numbers of focal or limbic features. The semiology of FS varied widely among children, and symptoms suggestive of focal onset were frequent. FS of focal onset may be more common than is generally thought. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. The dispersion-focalization theory of sound systems

    Science.gov (United States)

    Schwartz, Jean-Luc; Abry, Christian; Boë, Louis-Jean; Vallée, Nathalie; Ménard, Lucie

    2005-04-01

    The Dispersion-Focalization Theory states that sound systems in human languages are shaped by two major perceptual constraints: dispersion driving auditory contrast towards maximal or sufficient values [B. Lindblom, J. Phonetics 18, 135-152 (1990)] and focalization driving auditory spectra towards patterns with close neighboring formants. Dispersion is computed from the sum of the inverse squared inter-spectra distances in the (F1, F2, F3, F4) space, using a non-linear process based on the 3.5 Bark critical distance to estimate F2'. Focalization is based on the idea that close neighboring formants produce vowel spectra with marked peaks, easier to process and memorize in the auditory system. Evidence for increased stability of focal vowels in short-term memory was provided in a discrimination experiment on adult French subjects [J. L. Schwartz and P. Escudier, Speech Comm. 8, 235-259 (1989)]. A reanalysis of infant discrimination data shows that focalization could well be the responsible for recurrent discrimination asymmetries [J. L. Schwartz et al., Speech Comm. (in press)]. Recent data about children vowel production indicate that focalization seems to be part of the perceptual templates driving speech development. The Dispersion-Focalization Theory produces valid predictions for both vowel and consonant systems, in relation with available databases of human languages inventories.

  13. Widespread EEG changes precede focal seizures.

    Directory of Open Access Journals (Sweden)

    Piero Perucca

    Full Text Available The process by which the brain transitions into an epileptic seizure is unknown. In this study, we investigated whether the transition to seizure is associated with changes in brain dynamics detectable in the wideband EEG, and whether differences exist across underlying pathologies. Depth electrode ictal EEG recordings from 40 consecutive patients with pharmacoresistant lesional focal epilepsy were low-pass filtered at 500 Hz and sampled at 2,000 Hz. Predefined EEG sections were selected immediately before (immediate preictal, and 30 seconds before the earliest EEG sign suggestive of seizure activity (baseline. Spectral analysis, visual inspection and discrete wavelet transform were used to detect standard (delta, theta, alpha, beta and gamma and high-frequency bands (ripples and fast ripples. At the group level, each EEG frequency band activity increased significantly from baseline to the immediate preictal section, mostly in a progressive manner and independently of any modification in the state of vigilance. Preictal increases in each frequency band activity were widespread, being observed in the seizure-onset zone and lesional tissue, as well as in remote regions. These changes occurred in all the investigated pathologies (mesial temporal atrophy/sclerosis, local/regional cortical atrophy, and malformations of cortical development, but were more pronounced in mesial temporal atrophy/sclerosis. Our findings indicate that a brain state change with distinctive features, in the form of unidirectional changes across the entire EEG bandwidth, occurs immediately prior to seizure onset. We postulate that these changes might reflect a facilitating state of the brain which enables a susceptible region to generate seizures.

  14. Focal Segmental Glomerulosclerosis: A Single Center Experience

    Directory of Open Access Journals (Sweden)

    Yavuz Ayar

    2016-09-01

    Full Text Available Aim: Focal segmental glomerulosclerosis (FSGS is one of the most common glomerulonephritis (GNP worldwide. Despite treatment, it may progress to end-stage renal disease. In the present study, we compared clinical and histopathological data on FSGS with primary and secondary GNP retrospectively. Methods: We retrospectively analyzed data on clinical and laboratory findings, treatment response, and risk factors associated with mortality in patients, who had been diagnosed with FSGS and other GNP via renal biopsy between January 2009 and December 2014. The average follow-up time was 22 (8-76 months. Results: FSGS and primary GNP were more frequently seen in males than in females (55.9% vs. 65.3%, p=0.033. Nephrotic syndrome was more common in patients with FSGS (41.2% and primary GNP (57.7%, while chronic renal disease was more frequent in patients with secondary GNP (35%. In FSGS, the complete remission rate was 54.4%. 63.2% of patients had continued to receive treatment. According to the biopsy findings, interstitial inflammation and fibrosis were observed in 100% and 98.5% of patients with FSGS, respectively (p=0.010 and p<0.001, respectively. Serum albumin level was found to be increased and proteinuria, total cholesterol, triglyceride, and LDL levels to be decreased after treatment (p<0.001. Serum creatinine levels and type of GNP (secondary GNP were detected to be 1.48 and 8.14 fold increased in mortality analysis, respectively. Conclusion: Renal biopsy is the gold standard for the diagnosis of glomerular diseases. Renal function at the time of diagnosis, follow-up and appropriate immunosuppressive therapy have effects on mortality and clinical progress in FSGS as is the case in all GNPs.

  15. Focal Length Affects Depicted Shape and Perception of Facial Images.

    Directory of Open Access Journals (Sweden)

    Vít Třebický

    Full Text Available Static photographs are currently the most often employed stimuli in research on social perception. The method of photograph acquisition might affect the depicted subject's facial appearance and thus also the impression of such stimuli. An important factor influencing the resulting photograph is focal length, as different focal lengths produce various levels of image distortion. Here we tested whether different focal lengths (50, 85, 105 mm affect depicted shape and perception of female and male faces. We collected three portrait photographs of 45 (22 females, 23 males participants under standardized conditions and camera setting varying only in the focal length. Subsequently, the three photographs from each individual were shown on screen in a randomized order using a 3-alternative forced-choice paradigm. The images were judged for attractiveness, dominance, and femininity/masculinity by 369 raters (193 females, 176 males. Facial width-to-height ratio (fWHR was measured from each photograph and overall facial shape was analysed employing geometric morphometric methods (GMM. Our results showed that photographs taken with 50 mm focal length were rated as significantly less feminine/masculine, attractive, and dominant compared to the images taken with longer focal lengths. Further, shorter focal lengths produced faces with smaller fWHR. Subsequent GMM revealed focal length significantly affected overall facial shape of the photographed subjects. Thus methodology of photograph acquisition, focal length in this case, can significantly affect results of studies using photographic stimuli perhaps due to different levels of perspective distortion that influence shapes and proportions of morphological traits.

  16. Seismic Evidence for Conjugate Slip and Block Rotation Within the San Andreas Fault System, Southern California

    Science.gov (United States)

    Nicholson, Craig; Seeber, Leonardo; Williams, Patrick; Sykes, Lynn R.

    1986-08-01

    The pattern of seismicity in southern California indicates that much of the activity is presently occurring on secondary structures, several of which are oriented nearly orthogonal to the strikes of the major through-going faults. Slip along these secondary transverse features is predominantly left-lateral and is consistent with the reactivation of conjugate faults by the current regional stress field. Near the intersection of the San Jacinto and San Andreas faults, however, these active left-lateral faults appear to define a set of small crustal blocks, which in conjunction with both normal and reverse faulting earthquakes, suggests contemporary clockwise rotation as a result of regional right-lateral shear. Other left-lateral faults representing additional rotating block systems are identified in adjacent areas from geologic and seismologic data. Many of these structures predate the modern San Andreas system and may control the pattern of strain accumulation in southern California. Geodetic and paleomagnetic evidence confirm that block rotation by strike-slip faulting is nearly ubiquitous, particularly in areas where shear is distributed, and that it accommodates both short-term elastic and long-term nonelastic strain. A rotating block model accounts for a number of structural styles characteristic of strike-slip deformation in California, including: variable slip rates and alternating transtensional and transpressional features observed along strike of major wrench faults; domains of evenly-spaced antithetic faults that terminate against major fault boundaries; continued development of bends in faults with large lateral displacements; anomalous focal mechanisms; and differential uplift in areas otherwise expected to experience extension and subsidence. Since block rotation requires a detachment surface at depth to permit rotational movement, low-angle structures like detachments, of either local or regional extent, may be involved in the contemporary strike-slip

  17. The design of LMJ focal spots for indirect drive experiments

    International Nuclear Information System (INIS)

    Le Garrec, B J; Sajer, J M

    2008-01-01

    LMJ is a 240 high power laser beam facility for achieving laser matter interaction experiments, high energy density science, including the demonstration of fusion ignition through Inertial Confinement. The Laser Integration Line (LIL) facility is currently a 4-beam prototype for LMJ. The intensity I 0 at the focal spot centre drives hydrodynamic and plasma instabilities and the intensity in the wings must be low to go through the laser entrance Hohlraum. A simple model has been developed to compute the LMJ focal spot. The model gives the intensity at the centre as a function of the focal spot area at 3% of the maximum

  18. Focal cemento-osseous dysplasia: review and a case report.

    Science.gov (United States)

    Salem, Y M Y; Osman, Y I; Norval, E J G

    2010-10-01

    Focal cemento-osseous dysplasia is a benign fibro-osseous condition that can be seen in dentate and edentulous patients. It is an asymptomatic lesion and needs no treatment; however follow-up is essential due to the possibility that focal cemento-osseous dysplasia can progress to a condition called florid osseous dysplasia that involves multiple sites. A case report is presented here, along with a review of the differential diagnoses considered in order to reach a final diagnosis of focal cemento-osseous dysplasia.

  19. Benign focal liver lesions: discrimination from malignant mimickers.

    Science.gov (United States)

    Alobaidi, Mohammad; Shirkhoda, Ali

    2004-01-01

    Focal lesions of the liver often have various imaging characteristics which may be interpreted as either benign or malignant. Understanding the underlying pathophysiology of these liver lesions may lead to characteristic imaging manifestations, which direct the radiologist to the diagnosis. Benign lesions include congenital hepatic cyst, autosomal dominant polycystic disease, hemangioma, focal nodular hyperplasia (FNH), hepatic adenoma, inflammatory pseudotumor, peliosis hepatis, focal fatty infiltration, hamartoma, and infectious processes such as hepatic abscess, echinococcal cyst, and candidiasis. Characteristic imaging features, clinical symptoms, and treatment/prognosis will be discussed. Emphasis will be placed on key reliable features of each disease to develop a method of discriminating these lesions from other benign and malignant disorders.

  20. Dual-layer electrode-driven liquid crystal lens with electrically tunable focal length and focal plane

    Science.gov (United States)

    Zhang, Y. A.; Lin, C. F.; Lin, J. P.; Zeng, X. Y.; Yan, Q.; Zhou, X. T.; Guo, T. L.

    2018-04-01

    Electric-field-driven liquid crystal (ELC) lens with tunable focal length and their depth of field has been extensively applied in 3D display and imaging systems. In this work, a dual-layer electrode-driven liquid crystal (DELC) lens with electrically tunable focal length and controllable focal plane is demonstrated. ITO-SiO2-AZO electrodes with the dual-layer staggered structure on the top substrate are used as driven electrodes within a LC cell, which permits the establishment of an alternative controllability. The focal length of the DELC lens can be adjusted from 1.41 cm to 0.29 cm when the operating voltage changes from 15 V to 40 V. Furthermore, the focal plane of the DELC lens can selectively move by changing the driving method of the applied voltage to the next driven electrodes. This work demonstrates that the DELC lens has potential applications in imaging systems because of electrically tunable focal length and controllable focal plane.

  1. DEPDC5 takes a second hit in familial focal epilepsy.

    Science.gov (United States)

    Anderson, Matthew P

    2018-04-30

    Loss-of-function mutations in a single allele of the gene encoding DEP domain-containing 5 protein (DEPDC5) are commonly linked to familial focal epilepsy with variable foci; however, a subset of patients presents with focal cortical dysplasia that is proposed to result from a second-hit somatic mutation. In this issue of the JCI, Ribierre and colleagues provide several lines of evidence to support second-hit DEPDC5 mutations in this disorder. Moreover, the authors use in vivo, in utero electroporation combined with CRISPR-Cas9 technology to generate a murine model of the disease that recapitulates human manifestations, including cortical dysplasia-like changes, focal seizures, and sudden unexpected death. This study provides important insights into familial focal epilepsy and provides a preclinical model for evaluating potential therapies.

  2. Managing focal fields of vector beams with multiple polarization singularities.

    Science.gov (United States)

    Han, Lei; Liu, Sheng; Li, Peng; Zhang, Yi; Cheng, Huachao; Gan, Xuetao; Zhao, Jianlin

    2016-11-10

    We explore the tight focusing behavior of vector beams with multiple polarization singularities, and analyze the influences of the number, position, and topological charge of the singularities on the focal fields. It is found that the ellipticity of the local polarization states at the focal plane could be determined by the spatial distribution of the polarization singularities of the vector beam. When the spatial location and topological charge of singularities have even-fold rotation symmetry, the transverse fields at the focal plane are locally linearly polarized. Otherwise, the polarization state becomes a locally hybrid one. By appropriately arranging the distribution of the polarization singularities in the vector beam, the polarization distributions of the focal fields could be altered while the intensity maintains unchanged.

  3. Focal myositis of lower extremity responsive to botulinum A toxin.

    Science.gov (United States)

    Mitrovic, Josko; Prka, Zeljko; Zic, Rado; Marusic, Srecko; Morovic-Vergles, Jadranka

    2014-01-01

    Focal myositis is a rare, mostly benign disease (pseudotumor) of skeletal muscle, histopathologically characterized by interstitial myositis and tumorous enlargement of a single muscle. The etiology of focal myositis remains unknown; however, localized myopathy has been postulated to be caused by denervation lesions. This case report describes a patient that presented with clinical, laboratory, electromyoneurography, and magnetic resonance imaging features of focal myositis complicated with intervertebral disk protrusion in the lumbosacral spine affected with radicular distress. In most cases, focal myositic lesions show spontaneous regression, relapses are rare, and long-term prognosis is good. There is a wide spectrum of therapeutic options, from no therapy at all through nonsteroidal antirheumatics and glucocorticoids to radiotherapy, surgical excision, and immunosuppressants. In the patient presented, treatment with glucocorticoids, methotrexate, and surgical excision failed to produce satisfactory results. Clinical improvement, pain relief, and reduction in lower leg volume were only achieved by local infiltration of botulinum A toxin.

  4. Mechanical design and analysis of focal plate for gravity deformation

    Science.gov (United States)

    Wang, Jianping; Chu, Jiaru; Hu, Hongzhuan; Li, Kexuan; Zhou, Zengxiang

    2014-07-01

    The surface accuracy of astronomical telescope focal plate is a key indicator to precision stellar observation. To conduct accurate deformation measurement for focal plate in different status, a 6-DOF hexapod platform was used for attitude adjustment. For the small adjustment range of a classic 6-DOF hexapod platform, an improved structural arrangement method was proposed in the paper to achieve ultimate adjustment of the focal plate in horizontal and vertical direction. To validate the feasibility of this method, an angle change model which used ball hinge was set up for the movement and base plate. Simulation results in MATLAB suggested that the ball hinge angle change of movement and base plate is within the range of the limiting angle in the process of the platform plate adjusting to ultimate attitude. The proposed method has some guiding significance for accurate surface measurement of focal plate.

  5. FOCAL CORTICAL DYSPLASIAS: CLINICAL AND ELECTRO-NEUROIMAGING CHARACTERISTICS

    Directory of Open Access Journals (Sweden)

    K. Yu. Mukhin

    2016-01-01

    Full Text Available In spite of a notable advance made in epileptology, resistant epilepsies account for approximately 30 % of all forms of epilepsy particularly in patients with focal seizures. One of the main causes of therapy-resistant focal epilepsies is focal cortical dysplasias (FCD. This term was first introduced by D. Taylor et al. in 1971. FCD belongs to abnormal cortical development. Among all abnormalities of cortical development, FCD in surgically treated children amounts to 75 %. FCD is the most common cause of resistant epilepsy in children and the most frequent reason for diagnosing cryptogenic focal epilepsy with intractable seizures. The author gives a detailed literature review dedicated to FCD as a cause of resistant epilepsy, including the classification and histologic characteristics of FCD, its clinical manifestations and prognosis, and approaches to medical and surgical treatments. 

  6. Electrocorticographic discharge patterns in glioneuronal tumors and focal cortical dysplasia

    NARCIS (Netherlands)

    Ferrier, Cyrille H.; Aronica, Eleanora; Leijten, Frans S. S.; Spliet, Wim G. M.; van Huffelen, Alexander C.; van Rijen, Peter C.; Binnie, Colin D.

    2006-01-01

    PURPOSE: To determine whether highly epileptiform electrocorticographical discharge patterns occur in patients with glioneuronal tumors (GNTs) and focal cortical dysplasia (FCD) and whether specific histopathological features are related to such patterns. METHODS: The series consists of operated

  7. Adult-onset Rasmussen encephalitis associated with focal cortical dysplasia.

    Science.gov (United States)

    Hohenbichler, Katharina; Lelotte, Julie; Lhommel, Renaud; Tahry, Riëm El; Vrielynck, Pascal; Santos, Susana Ferrao

    2017-12-01

    Rasmussen encephalitis is a rare, devastating condition, typically presenting in childhood. Cases of adult-onset Rasmussen have also been described, but the clinical picture is less defined, rendering final diagnosis difficult. We present a case of adult-onset Rasmussen encephalitis with dual pathology, associated with focal cortical dysplasia and encephalitis. We interpreted the Rasmussen encephalitis to be caused by severe and continuous epileptic activity due to focal cortical dysplasia. The best therapeutic approach for such cases remains unclear.

  8. Focal plane for the next generation of earth observation instruments

    Science.gov (United States)

    Pranyies, P.; Toubhans, I.; Badoil, B.; Tanguy, F.; Descours, Francis

    2017-09-01

    Sodern is the French focal plane provider for Earth Observation (EO) satellites. Since the 1980's, Sodern has played an active role first in the SPOT program. Within the two-spacecraft constellation Pleiades 1A/1B over the next years, Sodern introduced advanced technologies as Silicon Carbide (SiC) focal plane structure and multispectral strip filters dedicated to multiple-lines detectors.

  9. Inverse-designed stretchable metalens with tunable focal distance

    Science.gov (United States)

    Callewaert, Francois; Velev, Vesselin; Jiang, Shizhou; Sahakian, Alan Varteres; Kumar, Prem; Aydin, Koray

    2018-02-01

    In this paper, we present an inverse-designed 3D-printed all-dielectric stretchable millimeter wave metalens with a tunable focal distance. A computational inverse-design method is used to design a flat metalens made of disconnected polymer building blocks with complex shapes, as opposed to conventional monolithic lenses. The proposed metalens provides better performance than a conventional Fresnel lens, using lesser amount of material and enabling larger focal distance tunability. The metalens is fabricated using a commercial 3D-printer and attached to a stretchable platform. Measurements and simulations show that the focal distance can be tuned by a factor of 4 with a stretching factor of only 75%, a nearly diffraction-limited focal spot, and with a 70% relative focusing efficiency, defined as the ratio between power focused in the focal spot and power going through the focal plane. The proposed platform can be extended for design and fabrication of multiple electromagnetic devices working from visible to microwave radiation depending on scaling of the devices.

  10. Thermomechanical architecture of the VIS focal plane for Euclid

    International Nuclear Information System (INIS)

    Martignac, Jerome; Carty, Michael; Tourette, Thierry; Bachet, Damien; Berthe, Michel; Augueres, Jean-Louis; Amiaux, Jerome; Fontignie, Jean; Horeau, Benoit; Renaud, Diana

    2014-01-01

    One of the main challenges for current and near future space experiments is the increase of focal plane complexity in terms of amount of pixels. In the frame work of the ESA Euclid mission to be launched in 2020, the Euclid Consortium is developing an extremely large and stable focal plane for the VIS instrument. CEA has developed the thermomechanical architecture of that Focal Plane taking into account all the very stringent performance and mission related requirements. The VIS Focal Plane Assembly integrates 36 CCDs (operated at 150 K) connected to their front end electronics (operated at 280 K) as to obtain one of the largest focal plane (0.6 billion pixels) ever built for space application after the GAIA one. The CCDs are CCD273 type specially designed and provided by the e2v company under ESA contract, front end electronics is studied and provided by MSSL. In this paper we first recall the specific requirements that have driven the overall architecture of the VIS-FPA and especially the solutions proposed to cope with the scientific needs of an extremely stable focal plane, both mechanically and thermally. The mechanical structure based on SiC material used for the cold sub assembly supporting the CCDs is detailed. We describe also the modular architecture concept that we have selected taking into account AIT-AIV and programmatic constraints. (authors)

  11. Blaschko Linear Enamel Defects - A Marker for Focal Dermal Hypoplasia: Case Report of Focal Dermal Hypoplasia

    Directory of Open Access Journals (Sweden)

    Stefan Gysin

    2015-05-01

    Full Text Available Focal dermal hypoplasia (FDH is a rare genetic skin disorder. The inheritance of FDH or Goltz-Gorlin syndrome is X-linked dominant and the disease is associated with a PORCN gene mutation. This gene plays a key role in the Wnt pathway, which has an impact on embryonic development. Every tissue derived from meso- and ectoderm can be affected. Patients suffer from cutaneous, ocular, osseous, oral and dental defects. The skin and dental alterations manifest along the Blaschko lines. We present a woman (born in 1962 suffering from FDH with congenital skin changes and Blaschko linear enamel defects. Typical symptoms (e.g. fat herniations, scoliosis, syndactyly, microphthalmia, caries and alopecia plus vertical grooving of all teeth gave a first indication. Molecular genetic testing confirmed the definitive diagnosis of FDH. We hypothesize that, in the context of typical skin changes, visible Blaschko lines on the teeth in the form of vertical grooves are almost pathognomonic for FDH.

  12. The Kumamoto Mw7.1 mainshock: deep initiation triggered by the shallow foreshocks

    Science.gov (United States)

    Shi, Q.; Wei, S.

    2017-12-01

    The Kumamoto Mw7.1 earthquake and its Mw6.2 foreshock struck the central Kyushu region in mid-April, 2016. The surface ruptures are characterized with multiple fault segments and a mix of strike-slip and normal motion extended from the intersection area of Hinagu and Futagawa faults to the southwest of Mt. Aso. Despite complex surface ruptures, most of the finite fault inversions use two fault segments to approximate the fault geometry. To study the rupture process and the complex fault geometry of this earthquake, we performed a multiple point source inversion for the mainshock using the data on 93 K-net and Kik-net stations. With path calibration from the Mw6.0 foreshock, we selected the frequency ranges for the Pnl waves (0.02 0.26 Hz) and surface waves (0.02 0.12 Hz), as well as the components that can be well modeled with the 1D velocity model. Our four-point-source results reveal a unilateral rupture towards Mt. Aso and varying fault geometries. The first sub-event is a high angle ( 79°) right-lateral strike-slip event at the depth of 16 km on the north end of the Hinagu fault. Notably the two M>6 foreshocks is located by our previous studies near the north end of the Hinagu fault at the depth of 5 9 km, which may give rise to the stress concentration at depth. The following three sub-events are distributed along the surface rupture of the Futagawa fault, with focal depths within 4 10 km. Their focal mechanisms present similar right-lateral fault slips with relatively small dip angles (62 67°) and apparent normal-fault component. Thus, the mainshock rupture initiated from the relatively deep part of the Hinagu fault and propagated through the fault-bend toward NE along the relatively shallow part of the Futagawa fault until it was terminated near Mt. Aso. Based on the four-point-source solution, we conducted a finite-fault inversion and obtained a kinematic rupture model of the mainshock. We then performed the Coulomb Stress analyses on the two foreshocks

  13. Southern Appalachian Regional Seismic Network

    Energy Technology Data Exchange (ETDEWEB)

    Chiu, S.C.C.; Johnston, A.C.; Chiu, J.M. [Memphis State Univ., TN (United States). Center for Earthquake Research and Information

    1994-08-01

    The seismic activity in the southern Appalachian area was monitored by the Southern Appalachian Regional Seismic Network (SARSN) since late 1979 by the Center for Earthquake Research and Information (CERI) at Memphis State University. This network provides good spatial coverage for earthquake locations especially in east Tennessee. The level of activity concentrates more heavily in the Valley and Ridge province of eastern Tennessee, as opposed to the Blue Ridge or Inner Piedmont. The large majority of these events lie between New York - Alabama lineament and the Clingman/Ocoee lineament, magnetic anomalies produced by deep-seated basement structures. Therefore SARSN, even with its wide station spacing, has been able to define the essential first-order seismological characteristics of the Southern Appalachian seismic zone. The focal depths of the southeastern U.S. earthquakes concentrate between 8 and 16 km, occurring principally beneath the Appalachian overthrust. In cross-sectional views, the average seismicity is shallower to the east beneath the Blue Ridge and Piedmont provinces and deeper to the west beneath the Valley and Ridge and the North American craton. Results of recent focal mechanism studies by using the CERI digital earthquake catalog between October, 1986 and December, 1991, indicate that the basement of the Valley and Ridge province is under a horizontal, NE-SW compressive stress. Right-lateral strike-slip faulting on nearly north-south fault planes is preferred because it agrees with the trend of the regional magnetic anomaly pattern.

  14. Southern Appalachian Regional Seismic Network

    International Nuclear Information System (INIS)

    Chiu, S.C.C.; Johnston, A.C.; Chiu, J.M.

    1994-08-01

    The seismic activity in the southern Appalachian area was monitored by the Southern Appalachian Regional Seismic Network (SARSN) since late 1979 by the Center for Earthquake Research and Information (CERI) at Memphis State University. This network provides good spatial coverage for earthquake locations especially in east Tennessee. The level of activity concentrates more heavily in the Valley and Ridge province of eastern Tennessee, as opposed to the Blue Ridge or Inner Piedmont. The large majority of these events lie between New York - Alabama lineament and the Clingman/Ocoee lineament, magnetic anomalies produced by deep-seated basement structures. Therefore SARSN, even with its wide station spacing, has been able to define the essential first-order seismological characteristics of the Southern Appalachian seismic zone. The focal depths of the southeastern U.S. earthquakes concentrate between 8 and 16 km, occurring principally beneath the Appalachian overthrust. In cross-sectional views, the average seismicity is shallower to the east beneath the Blue Ridge and Piedmont provinces and deeper to the west beneath the Valley and Ridge and the North American craton. Results of recent focal mechanism studies by using the CERI digital earthquake catalog between October, 1986 and December, 1991, indicate that the basement of the Valley and Ridge province is under a horizontal, NE-SW compressive stress. Right-lateral strike-slip faulting on nearly north-south fault planes is preferred because it agrees with the trend of the regional magnetic anomaly pattern

  15. Pan-African deformations in the basement of the Negele area, southern Ethiopia

    Science.gov (United States)

    Yihunie, Tadesse

    2002-03-01

    Polydeformed and metamorphosed Neoproterozoic rocks of the East African Orogen in the Negele area constituted three lithostructurally distinct and thrust-bounded terranes. These are, from west to east, the Kenticha, Alghe and Bulbul terranes. The Kenticha and Bulbul terranes are metavolcano-sedimentary and ultramafic sequences, representing parts of the Arabian-Nubian Shield (ANS), which are welded to the central Alghe gneissic terrane of the Mozambique Belt affinity along N-S-trending sheared thrust contacts. Structural data suggest that the Negele basement had evolved through three phases of deformation. During D1 (folding) deformation, north-south upright and inclined folds with north-trending axes were developed. East and west-verging thrusts, right-lateral shearing along the north-oriented Kenticha and Bulbul thrust contacts and related structural elements were developed during D2 (thrusting) deformation. The pervasive D1 event is interpreted to have occurred at 620-610 Ma and the D2 event ended prior to 554 Ma. Right-lateral strike-slips along thrust contacts are interpreted to have been initiated during late D2. During D3, left-lateral strike-slip along the Wadera Shear Zone and respective strike-slip movements along conjugate set of shear zones were developed in the Alghe terrane, and are interpreted to have occurred later than 557 Ma. The structural data suggest that eastward thrusting of the Kenticha and westward tectonic transport of the Bulbul sequences over the Alghe gneissic terrane of the Mozambique Belt, during D2, were accompanied by right-lateral strike-slip displacements along thrust contacts. Right-lateral strike-slip movements along the Kenticha thrust contact, further suggest northward movement of the Kenticha sequence during the Pan-African orogeny in the Neoproterozoic. Left-lateral strike-slip along the orogen-parallel NNE-SSW Wadera Shear Zone and strike-slip movements along a conjugate set of shear zones completed final terrane

  16. CT findings of focal organizing pneumonia: correlation with pathologic findings

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yang Soo; Kim, Young Goo; Park, Un Sup [College of Medicine, Chungang University, Seoul (Korea, Republic of)

    1994-11-15

    To evaluate the CT findings of focal organizing pneumonia and to correlate them with pathologic findings to help differentiating from lung cancer. We evaluated radiologic and pathologic findings of five patients with solitary pulmonary nodule which were confirmed as focal organizing pneumonia pathologically. On CT scan, focal organizing pneumonia had irregular margin contacting the pleura in all five cases. The shape of the nodules were spherical to wedge or elliptical and the size from 3.5cm to 5.5cm(average 4.2 cm) in largest diameter. On postcontrast CT scan, all nodules showed enhancement and four cases showed central low density components. Two nodules contained air within the nodule. In four cases, pleural changes such as effusion and/or focal thickening were noted. No lymphadenopathy was found in all cases. Pathologically, the enhancing portion on CT showed findings of organizing pneumonia such as granulation tissue with fibroblast proliferation in alveolar space and interstitial thickening. The central low density areas on CT were due to ischemic necrosis, abscess and exudate, transudate and infiltration of foamy histiocyte. The possibility of focal organizing pneumonia should be considered when peripherally located solitary pulmonary nodule had enhancing component with no combined lymphadenopathy on CT scan.

  17. CT findings of focal organizing pneumonia: correlation with pathologic findings

    International Nuclear Information System (INIS)

    Kim, Yang Soo; Kim, Young Goo; Park, Un Sup

    1994-01-01

    To evaluate the CT findings of focal organizing pneumonia and to correlate them with pathologic findings to help differentiating from lung cancer. We evaluated radiologic and pathologic findings of five patients with solitary pulmonary nodule which were confirmed as focal organizing pneumonia pathologically. On CT scan, focal organizing pneumonia had irregular margin contacting the pleura in all five cases. The shape of the nodules were spherical to wedge or elliptical and the size from 3.5cm to 5.5cm(average 4.2 cm) in largest diameter. On postcontrast CT scan, all nodules showed enhancement and four cases showed central low density components. Two nodules contained air within the nodule. In four cases, pleural changes such as effusion and/or focal thickening were noted. No lymphadenopathy was found in all cases. Pathologically, the enhancing portion on CT showed findings of organizing pneumonia such as granulation tissue with fibroblast proliferation in alveolar space and interstitial thickening. The central low density areas on CT were due to ischemic necrosis, abscess and exudate, transudate and infiltration of foamy histiocyte. The possibility of focal organizing pneumonia should be considered when peripherally located solitary pulmonary nodule had enhancing component with no combined lymphadenopathy on CT scan

  18. Detection is unaffected by the deployment of focal attention

    Directory of Open Access Journals (Sweden)

    Jeff eMoher

    2013-05-01

    Full Text Available There has been much debate regarding how much information humans can extract from their environment without the use of limited attentional resources. In a recent study, Theeuwes, Van der Burg, and Belopolsky (2008 argued that even detection of simple feature targets is not possible without selection by focal attention. Supporting this claim, they found response time benefits in a simple feature (color detection task when a target letter’s identity was repeated on consecutive trials, suggesting that the letter was selected by focal attention and identified prior to detection. This intertrial repetition benefit remained even when observers were required to simultaneously identify a central digit. However, we found that intertrial repetition benefits disappeared when a simple color target was presented among a heterogeneously (rather than homogeneously colored set of distractors, thus reducing its bottom-up salience. Still, detection performance remained high. Thus, detection performance was unaffected by whether a letter was focally attended and identified prior to detection or not. Intertrial identity repetition benefits also disappeared when observers were required to perform a simultaneous, attention-demanding central task (Experiment 2, or when unfamiliar Chinese characters were used (Experiment 3. Together, these results suggest that while shifts of focal attention can be affected by target salience, by the availability of excess cognitive resources, and by target familiarity, detection performance itself is unaffected by these manipulations and is thus unaffected by the deployment of focal attention.

  19. EEG dynamical correlates of focal and diffuse causes of coma.

    Science.gov (United States)

    Kafashan, MohammadMehdi; Ryu, Shoko; Hargis, Mitchell J; Laurido-Soto, Osvaldo; Roberts, Debra E; Thontakudi, Akshay; Eisenman, Lawrence; Kummer, Terrance T; Ching, ShiNung

    2017-11-15

    Rapidly determining the causes of a depressed level of consciousness (DLOC) including coma is a common clinical challenge. Quantitative analysis of the electroencephalogram (EEG) has the potential to improve DLOC assessment by providing readily deployable, temporally detailed characterization of brain activity in such patients. While used commonly for seizure detection, EEG-based assessment of DLOC etiology is less well-established. As a first step towards etiological diagnosis, we sought to distinguish focal and diffuse causes of DLOC through assessment of temporal dynamics within EEG signals. We retrospectively analyzed EEG recordings from 40 patients with DLOC with consensus focal or diffuse culprit pathology. For each recording, we performed a suite of time-series analyses, then used a statistical framework to identify which analyses (features) could be used to distinguish between focal and diffuse cases. Using cross-validation approaches, we identified several spectral and non-spectral EEG features that were significantly different between DLOC patients with focal vs. diffuse etiologies, enabling EEG-based classification with an accuracy of 76%. Our findings suggest that DLOC due to focal vs. diffuse injuries differ along several electrophysiological parameters. These results may form the basis of future classification strategies for DLOC and coma that are more etiologically-specific and therefore therapeutically-relevant.

  20. A targeted resequencing gene panel for focal epilepsy.

    Science.gov (United States)

    Hildebrand, Michael S; Myers, Candace T; Carvill, Gemma L; Regan, Brigid M; Damiano, John A; Mullen, Saul A; Newton, Mark R; Nair, Umesh; Gazina, Elena V; Milligan, Carol J; Reid, Christopher A; Petrou, Steven; Scheffer, Ingrid E; Berkovic, Samuel F; Mefford, Heather C

    2016-04-26

    We report development of a targeted resequencing gene panel for focal epilepsy, the most prevalent phenotypic group of the epilepsies. The targeted resequencing gene panel was designed using molecular inversion probe (MIP) capture technology and sequenced using massively parallel Illumina sequencing. We demonstrated proof of principle that mutations can be detected in 4 previously genotyped focal epilepsy cases. We searched for both germline and somatic mutations in 251 patients with unsolved sporadic or familial focal epilepsy and identified 11 novel or very rare missense variants in 5 different genes: CHRNA4, GRIN2B, KCNT1, PCDH19, and SCN1A. Of these, 2 were predicted to be pathogenic or likely pathogenic, explaining ∼0.8% of the cohort, and 8 were of uncertain significance based on available data. We have developed and validated a targeted resequencing panel for focal epilepsies, the most important clinical class of epilepsies, accounting for about 60% of all cases. Our application of MIP technology is an innovative approach that will be advantageous in the clinical setting because it is highly sensitive, efficient, and cost-effective for screening large patient cohorts. Our findings indicate that mutations in known genes likely explain only a small proportion of focal epilepsy cases. This is not surprising given the established clinical and genetic heterogeneity of these disorders and underscores the importance of further gene discovery studies in this complex syndrome. © 2016 American Academy of Neurology.

  1. Terapia Interpessoal: um modelo breve e focal Interpersonal Therapy: a brief and focal model

    Directory of Open Access Journals (Sweden)

    Marcelo Feijó de Mello

    2004-06-01

    Full Text Available A psicoterapia é uma forma particular de tratamento em psiquiatria. Seu uso é amplamente difundido e conta com várias linhas de abordagem. OBJETIVO: Neste trabalho, o autor faz considerações a respeito da terapia interpessoal (TIP, uma forma breve e focal de psicoterapia. Inicialmente usada para o tratamento da depressão, teve seu espectro de ação ampliado para outros transtornos. A TIP pode ser dividida em 3 fases: inicial, quando é feito um diagnóstico do transtorno nomeando os sintomas ao paciente e diagnosticando o foco interpessoal a ser trabalhado; fase intermediária, onde se trabalha o foco; e fase final, quando o paciente é encorajado a reconhecer e consolidar seus ganhos para usá-los no futuro. MÉTODOS: O autor faz uma revisão das evidências científicas da eficácia da TIP no tratamento da depressão. CONCLUSÕES: Os resultados mostram que a TIP é uma forma terapêutica eficaz e bem tolerada de tratamento para a depressão.Psychotherapy is a particular form of treatment in Psychiatry. Its use is widespread and has many different approaches. OBJECTIVE: In this article, the author makes some considerations about Interpersonal Therapy (IPT, a brief and focal psychotherapy. Initially created to treat depression, other researchers had successfully increase its spectrum. It could be divided in three phases. Initial, when the therapist makes the diagnosis of the disorder and also the interpersonal problematic is pointed out; the patient received a sick role. Intermediary when the focus is treated, and the final phase when the therapist encourages the patient to recognize and consolidate gains and prepare the patient to use it in the future. METHODS: It is stressed that IPT is a testable form of psychotherapy and the scientific evidences of its efficacy are showed. CONCLUSIONS: The results assure that IPT is an efficient form of psychotherapy for depression with a great acceptability from the patients.

  2. The 2016 seismic series in the south Alboran Sea: Seismotectonics, Coulomb Failure Stress changes and implications for the active tectonics in the area.

    Science.gov (United States)

    Alvarez-Gómez, José A.; Martín, Rosa; Pérez-López, Raul; Stich, Daniel; Cantavella, Juan V.; Martínez-Díaz, José J.; Morales, José; Soto, Juan I.; Carreño, Emilio

    2017-04-01

    The Southern Alboran Sea, particularly the area offshore Al Hoceima Bay, presents moderate but continuous seismic activity since the Mw 6.0 1994 Al Hoceima earthquake. The maximum magnitude occurred in the area was a Mw 6.3 earthquake in the 2004 Al Hoceima - Tamasint seismic series. Since then, the seismicity in the Al Hoceima area has been usual, with maximum seismic magnitudes around 4. An increase in the seismic rate was registered during 2015, especially from May, culminating in the seismic series in January 2016. The mainshock occurred on January 25th 2016 with a magnitude Mw 6.3 and it was preceded by a Mw 5.1 foreshock on January 21st. The seismic series took place at the western end of the Alboran Ridge. Towards the northeast the Alboran Ridge bends, and seems to be connected with the NW-SE right-lateral transtensional Yusuf Fault. The recorded seismicity is mainly located in the Alboran Ridge area and along the N-S Al-Idrisi Fault that seems to continue southwards, towards the Al Hoceima Bay. The focal mechanisms calculated previously in the area showed a left-lateral strike-slip faulting with some normal component in the Alboran Ridge; but always within a complex system of diffuse deformation and high rupture type variability. We have used 41 computed focal mechanisms of this seismic series to analyze its seismotectonics and structural characteristics. To group the focal mechanisms we used a clustering algorithm using the spatial distribution of the events and also the type of rupture mechanism. For each cluster we have obtained the composed focal mechanism, associating it to a particular fault or family of structures. We have tested the mechanical compatibility of these structures by Coulomb Failure Stress transfer modeling. The mainshock of the series occurred in the Al Idrisi Fault intersecting the western Alboran Ridge. This event triggered aftershocks and independent series in left-lateral strike-slip faults associated with the Al Idrisi Fault

  3. Role of scintigraphy in focally abnormal sonograms of fatty livers

    International Nuclear Information System (INIS)

    Lisbona, R.; Mishkin, S.; Derbekyan, V.; Novales-Diaz, J.A.; Roy, A.; Sanders, L.

    1988-01-01

    Fatty infiltration of the liver may cause a range of focal abnormalities on hepatic sonography which may simulate hepatic nodular lesions. Discrete deposits of fat or islands of normal tissue which are uninvolved by fatty infiltration may stand out as potential space-occupying lesions on the sonograms. Twelve patients with such focally abnormal ultrasound images were referred for liver scintigraphy with 133 Xe and /sup 99m/Tc colloidal SPECT studies to clarify the issue. These examinations helped identify, in nine of 12 patients, the innocent nature of the sonographic abnormalities which were simply related to the fat deposition process. Further, [/sup 99m/Tc]RBC scans defined the additional pathologic process in three patients in whom actual space-occupying lesions were indeed present in the liver. Scintigraphy has an important role to play in the understanding of focal hepatic ultrasound abnormalities particularly in unsuspected hepatic steatosis

  4. Role of scintigraphy in focally abnormal sonograms of fatty livers

    Energy Technology Data Exchange (ETDEWEB)

    Lisbona, R.; Mishkin, S.; Derbekyan, V.; Novales-Diaz, J.A.; Roy, A.; Sanders, L.

    1988-06-01

    Fatty infiltration of the liver may cause a range of focal abnormalities on hepatic sonography which may simulate hepatic nodular lesions. Discrete deposits of fat or islands of normal tissue which are uninvolved by fatty infiltration may stand out as potential space-occupying lesions on the sonograms. Twelve patients with such focally abnormal ultrasound images were referred for liver scintigraphy with /sup 133/Xe and /sup 99m/Tc colloidal SPECT studies to clarify the issue. These examinations helped identify, in nine of 12 patients, the innocent nature of the sonographic abnormalities which were simply related to the fat deposition process. Further, (/sup 99m/Tc)RBC scans defined the additional pathologic process in three patients in whom actual space-occupying lesions were indeed present in the liver. Scintigraphy has an important role to play in the understanding of focal hepatic ultrasound abnormalities particularly in unsuspected hepatic steatosis.

  5. US and CT findings in splenic focal lesions in AIDS

    International Nuclear Information System (INIS)

    Schinina, V.; Rizzi, E.B.; Mazzuoli, G.; Bibbolilno, C.; David, V.

    2000-01-01

    To evaluate the role of US and CT in focal splenic lesions in AIDS patients in relation to etiology. Material and Methods: A total of 66 patients with AIDS and focal splenic lesions were examined with sonography. CT with administration of contrast medium was performed in 12 cases. Results: Of the focal splenic lesions, 67% were correlated with an infective pathology with prevalence of Mycobacteria tuberculosis (75%), 26% were neoplastic and 6% splenic infarcts. The lesions were hypoechoic in 60% of the cases, while 10% were hypoanechoic and 1% anechoic. At CT, all lesions appeared hypodense, even after i.v. administration of contrast medium. Conclusion: The combination of echographic reports and clinical and laboratory data allows for a diagnosis that can be confirmed, and making a decision for effective therapy of AIDS is possible. CT does not provide any additional information

  6. Simulation of the Focal Spot of the Accelerator Bremsstrahlung Radiation

    Science.gov (United States)

    Sorokin, V.; Bespalov, V.

    2016-06-01

    Testing of thick-walled objects by bremsstrahlung radiation (BR) is primarily performed via high-energy quanta. The testing parameters are specified by the focal spot size of the high-energy bremsstrahlung radiation. In determining the focal spot size, the high- energy BR portion cannot be experimentally separated from the low-energy BR to use high- energy quanta only. The patterns of BR focal spot formation have been investigated via statistical modeling of the radiation transfer in the target material. The distributions of BR quanta emitted by the target for different energies and emission angles under normal distribution of the accelerated electrons bombarding the target have been obtained, and the ratio of the distribution parameters has been determined.

  7. MRI of a family with focal abnormalities of gyration

    International Nuclear Information System (INIS)

    Muntaner, L.; Perez-Ferron, J.J.; Herrera, M.; Rosell, J.; Taboada, D.; Climent, S.

    1997-01-01

    Focal abnormalities of gyration (FAG) are developmental disorders that may occur in isolated patients or, as in the case being reported, as part of a familial disorder. Analysis of individuals in a family spanning three generations was carried out using MRI. Abnormalities, present in all members of generations II and III, included focal cortical dysplasia (three patients), focal cortical infolding (two patients) and schizencephaly (one patient); associated minor anomalies, such as white matter abnormalities, were seen in the remaining three members of generations II and III. MRI recognition of FAG in the family being reported proved useful in defining their phenotypical expression and providing proper counselling for individual family members. (orig.). With 6 figs

  8. Protein kinase C involvement in focal adhesion formation

    DEFF Research Database (Denmark)

    Woods, A; Couchman, J R

    1992-01-01

    Matrix molecules such as fibronectin can promote cell attachment, spreading and focal adhesion formation. Although some interactions of fibronectin with cell surface receptors have now been identified, the consequent activation of intracellular messenger systems by cell/matrix interactions have...... still to be elucidated. We show here that the kinase inhibitors H7 and HA1004 reduce focal adhesion and stress fiber formation in response to fibronectin in a dose-dependent manner, and that activators of protein kinase C can promote their formation under conditions where they do not normally form....... Fibroblasts spread within 1h on substrata composed of fibronectin and formed focal adhesions by 3h, as monitored by interference reflection microscopy (IRM) and by labeling for talin, vinculin and integrin beta 1 subunits. In addition, stress fibers were visible. When cells were allowed to spread for 1h...

  9. Focal depth measurement of scanning helium ion microscope

    International Nuclear Information System (INIS)

    Guo, Hongxuan; Itoh, Hiroshi; Wang, Chunmei; Zhang, Han; Fujita, Daisuke

    2014-01-01

    When facing the challenges of critical dimension measurement of complicated nanostructures, such as of the three dimension integrated circuit, characterization of the focal depth of microscopes is important. In this Letter, we developed a method for characterizing the focal depth of a scanning helium ion microscope (HIM) by using an atomic force microscope tip characterizer (ATC). The ATC was tilted in a sample chamber at an angle to the scanning plan. Secondary electron images (SEIs) were obtained at different positions of the ATC. The edge resolution of the SEIs shows the nominal diameters of the helium ion beam at different focal levels. With this method, the nominal shapes of the helium ion beams were obtained with different apertures. Our results show that a small aperture is necessary to get a high spatial resolution and high depth of field images with HIM. This work provides a method for characterizing and improving the performance of HIM.

  10. Nodular focal fatty infiltration of the liver: CT appearance

    International Nuclear Information System (INIS)

    Baker, M.E.; Silverman, P.M.

    1985-01-01

    Focal fatty infiltration of the liver is a well recognized entity generally characterized by a nonspherical, low-density area without significant mass effect. CT usually distinguishes this from focal liver processes such as abscess or metastasis by its sharply marginated, geographic pattern and lack of mass effect on hepatic and portal veins. Recently, the authors formed a CT scan of the liver in one patient in whom fatty infiltration appeared nodular or rounded. The clinical presentation and radiographic and pathologic features form the basis of this report

  11. The radiological features of Goltz syndrome: Focal dermal hypoplasia

    International Nuclear Information System (INIS)

    Boothyrod, A.E.; Hall, C.M.

    1988-01-01

    Two female infants with Goltz syndrome (focal dermal hypoplasia) were recently investigated for severe feeding problems and failure to thrive. Both demonstrated severe skeletal malformations and marked gastrooesophageal reflux with laxity of the hiatus. One child (case 1) exhibited nasal regurgitation during feeding. Interestingly, both children had undergone surgery; Case 1 or a right parasagittal abdominal hernia associated with focal dermal hypoplasia of the abdominal wall and Case 2 for an exomphalos also associated with dermal hypoplasia. This observation suggests more widespread mesodermal abnormality. (orig./GDG)

  12. Focal myositis of the thigh: unusual MR pattern

    International Nuclear Information System (INIS)

    Llauger, Jaume; Palmer, Jaume; San Roman, Luis; Bague, Silvia; Matias-Guiu, Xavier; Doncel, Antonio

    2002-01-01

    Focal myositis is a commonly referenced, infrequently reported and poorly documented benign inflammatory pseudotumor which may be misdiagnosed clinically as a malignant tumor. We report the clinicopathologic features and magnetic resonance imaging findings in a case of focal myositis in the thigh of a 55-year-old woman. A different radiologic presentation of this disorder is described. The gross appearance of the lesion, previously undescribed, appears to be rather specific for such a pseudoneoplastic disorder, and correlates very well with the magnetic resonance imaging features. (orig.)

  13. Focal myositis of the thigh: unusual MR pattern

    Energy Technology Data Exchange (ETDEWEB)

    Llauger, Jaume; Palmer, Jaume; San Roman, Luis [Department of Radiology, Hospital de la Santa Creu i Sant Pau, Barcelona (Spain); Bague, Silvia; Matias-Guiu, Xavier [Department of Pathology, Hospital de la Santa Creu i Sant Pau, Barcelona (Spain); Doncel, Antonio [Department of Orthopedic Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona (Spain)

    2002-05-01

    Focal myositis is a commonly referenced, infrequently reported and poorly documented benign inflammatory pseudotumor which may be misdiagnosed clinically as a malignant tumor. We report the clinicopathologic features and magnetic resonance imaging findings in a case of focal myositis in the thigh of a 55-year-old woman. A different radiologic presentation of this disorder is described. The gross appearance of the lesion, previously undescribed, appears to be rather specific for such a pseudoneoplastic disorder, and correlates very well with the magnetic resonance imaging features. (orig.)

  14. Magnetic-resonance-guided biopsy of focal liver lesions

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Ethan A. [University of Michigan Health System, Section of Pediatric Radiology, C.S. Mott Children' s Hospital, Department of Radiology, Ann Arbor, MI (United States); Grove, Jason J. [University of Michigan Health System, Division of Interventional Radiology, C.S. Mott Children' s Hospital, Department of Radiology, Ann Arbor, MI (United States); Der Spek, Abraham F.L.V. [University of Michigan Health System, Department of Anesthesiology, C.S. Mott Children' s Hospital, Ann Arbor, MI (United States); Jarboe, Marcus D. [University of Michigan Health System, Division of Interventional Radiology, C.S. Mott Children' s Hospital, Department of Radiology, Ann Arbor, MI (United States); University of Michigan Health System, Section of Pediatric Surgery, C.S. Mott Children' s Hospital, Department of Surgery, Ann Arbor, MI (United States)

    2017-05-15

    Image-guided biopsy techniques are widely used in clinical practice. Commonly used methods employ either ultrasound (US) or computed tomography (CT) for image guidance. In certain patients, US or CT guidance may be suboptimal, or even impossible, because of artifacts, suboptimal lesion visualization, or both. We recently began performing magnetic resonance (MR)-guided biopsy of focal liver lesions in select pediatric patients with lesions that are not well visualized by US or CT. This report describes our experience performing MR-guided biopsy of focal liver lesions, with case examples to illustrate innovative techniques and novel aspects of these procedures. (orig.)

  15. Magnetic electroanatomical mapping for ablation of focal atrial tachycardias.

    Science.gov (United States)

    Marchlinski, F; Callans, D; Gottlieb, C; Rodriguez, E; Coyne, R; Kleinman, D

    1998-08-01

    Uniform success for ablation of focal atrial tachycardias has been difficult to achieve using standard catheter mapping and ablation techniques. In addition, our understanding of the complex relationship between atrial anatomy, electrophysiology, and surface ECG P wave morphology remains primitive. The magnetic electroanatomical mapping and display system (CARTO) offers an on-line display of electrical activation and/or signal amplitude related to the anatomical location of the recorded sites in the mapped chamber. A window of electrical interest is established based on signals timed from an electrical reference that usually represents a fixed electrogram recording from the coronary sinus or the atrial appendage. This window of electrical interest is established to include atrial activation prior to the onset of the P wave activity associated with the site of origin of a focal atrial tachycardia. Anatomical and electrical landmarks are defined with limited fluoroscopic imaging support and more detailed global chamber and more focal atrial mapping can be performed with minimal fluoroscopic guidance. A three-dimensional color map representing atrial activation or voltage amplitude at the magnetically defined anatomical sites is displayed with on-line data acquisition. This display can be manipulated to facilitate viewing from any angle. Altering the zoom control, triangle fill threshold, clipping plane, or color range can all enhance the display of a more focal area of interest. We documented the feasibility of using this single mapping catheter technique for localizing and ablating focal atrial tachycardias. In a consecutive series of 8 patients with 9 focal atrial tachycardias, the use of the single catheter CARTO mapping system was associated with ablation success in all but one patient who had a left atrial tachycardia localized to the medial aspect of the orifice of the left atrial appendage. Only low power energy delivery was used in this patient because of the

  16. Regional cerebral blood flow in focal cortical epilepsy

    DEFF Research Database (Denmark)

    Hougaard, Kristina Dupont; Oikawa, T; Sveinsdottir, E

    1976-01-01

    Regional cerebral blood flow (rCBF) was studied in ten patients with focal cortical epilepsy. The blood flow was measured by the intra-arterial injection of xenon 133 (133Xe), and the isotope clearance was recorded by a multidetector scintillation camera with 254 detectors. Three patients were....... This finding accords with earlier studies. All nine patients studied in the interictal phase showed, either spontaneously or during activation by intermittent light, focal flow increases in areas presumed to comprise the epileptic focus. These interictal hyperemic foci probably reflect subictal neuronal...

  17. Incidental Detection of Temporary Focal FDG Retention in the Spleen

    Energy Technology Data Exchange (ETDEWEB)

    Park, Youn Joon; Lee, Jai Hyuen; Jee, Keum Nahn; Namgung, Hwan [Dankook Univ. College of Medicine, Seoul (Korea, Republic of)

    2011-06-15

    F 18 fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) is a valuable tool in discriminating malignancy from benign lesion. But because various false positive results reduce the diagnostic specificity, nuclear medicine physicians should be familiar with possible false positive cases. Although many cases of high FDG uptake mimicking malignancy have been reported, temporary intense focal FDG uptake of normal spleen has not been reported previously. We report herein a phenomenon of temporary intense focal FDG uptake of normal spleen without evidence of metastasis in a 46 year old woman with a history of anal cancer.

  18. Expansion characteristics of coronary stents in focal stenoses

    Directory of Open Access Journals (Sweden)

    Schmidt Wolfram

    2017-09-01

    Full Text Available The presented experimental in vitro approach was designed to assess the expansion behavior of stent systems in a resistant focal stenosis model with respect to a potential dog-boning effect. Five different stent systems (nominal diameter 3.0 mm were investigated. The focal stenosis was simulated by a stainless steel tube (ID ≤ 1.20 mm. Stent expansion was performed using a proprietary test device consisting of a test chamber with 37 °C water, 2-axis laser scanner and a pressure controller.

  19. Tectonic Implication of the 5th March 2005, Doublet Earthquake in Ilan, Taiwan

    Directory of Open Access Journals (Sweden)

    En-Chao Yeh

    2016-01-01

    Full Text Available The 5th March 2005 earthquake doublet focal mechanism was determined as strike-slip faulting from Harvard and BATS moment tensor inversion. However, based on first motion polarities, the first shock has a normal focal mechanism (Wu et al. 2008a. This discrepancy has caused a debate over the focal mechanism solution because different focal mechanisms have different tectonic implications. Based on the dislocation determination from Global Position System (GPS measurements, we find this event includes both tensile and strike-slip components. This finding illustrates the reason for the differences in the determined focal mechanisms using two different types of seismic data and analyzing methods. Field mapping and microstructure examination results indicate that the ductile deformation around the study area was characterized by the evolution from transpression to transtension with a predominant strike-slip component, but present-day active structures may be dominated by normal faulting. Thus, the active tensile slip result determined from dislocation modeling strongly suggests that the back arc extension of the Okinawa trough influences the stress state in this region, and changes the major transtension from strike-slip faulting to normal faulting.

  20. Focal symmetrical encephalomalacia in sheep Encefalomalacia focal simétrica em ovino

    Directory of Open Access Journals (Sweden)

    Luciano A. Pimentel

    2010-05-01

    Full Text Available Focal symmetrical encephalomalacia (FSE is the most prominent lesion seen in the chronic form of enterotoxemia by Clostridium perfringens type D. This paper reports FSE in sheep in Brazil. Six deaths occurred within a seven days period in a flock of 70, four to 30-month-old Santa Inês sheep in the state of Paraíba in the Brazilian semiarid. The flock was grazing a paddock of irrigated sprouting Cynodon dactylon (Tifton grass, and supplemented, ad libitum, with a concentrate of soybean, corn and wheat. Nervous signs included blindness and recumbence. A 19 month-old sheep was examined clinically and necropsied after a clinical course of three days. Gross lesions were herniation of the cerebellar vermis and multifocal, bilateral, symmetric brownish areas in the internal capsule, thalamus and cerebellar peduncles. Histologic lesions were multifocal, bilateral malacia with some neutrophils, swelling of blood vessels endothelium, perivascular edema, and hemorrhages. The flock was vaccinated, before the outbreak, with only one dose of Clostridium perfringens type D vaccine. Two factors are suggested to be important for the occurrence of the disease: insufficient immunity due to the incorrect vaccination; and high nutritional levels by the supplementation with highly fermentable carbohydrates.Encefalomalacia focal simétrica (EFS é a lesão mais proeminente vista nas formas subaguda ou crônica da enterotoxemia por Clostridium perfringens tipo D. Este trabalho relata EFS em ovinos no semiárido do estado da Paraíba. Seis ovinos morreram, em um período de sete dias, dentro de um rebanho de 70 animais, da raça Santa Inês, entre 4-30 meses de idade, que pastavam em piquete de Cynodon dactylon (capim Tifton, que estava rebrotando. Os ovinos eram suplementados com um concentrado de soja, trigo e milho. Os sinais nervosos incluíam cegueira e decúbito lateral. Um ovino de 19 meses de idade foi examinado clinicamente e necropsiado, depois de um curso

  1. Idiopathic focal segmental glomerulosclerosis: a favourable prognosis in untreated patients?

    NARCIS (Netherlands)

    Deegens, J.K.J.; Assmann, K.J.M.; Steenbergen, E.; Hilbrands, L.B.; Gerlag, P.G.G.; Jansen, J.L.; Wetzels, J.F.M.

    2005-01-01

    BACKGROUND: Patients with focal segmental glomerulosclerosis (FSGS) are considered to have a poor prognosis and spontaneous remissions are seldom reported. However, FSGS is not a single disease entity. Our aim was to describe the clinical course in initially untreated patients with recently

  2. Laser Beam Caustic Measurement with Focal Spot Analyser

    DEFF Research Database (Denmark)

    Olsen, Flemming Ove; Gong, Hui; Bagger, Claus

    2005-01-01

    In industrial applications of high power CO2-lasers the caustic characteristics of the laser beam have great effects on the performance of the lasers. A welldefined high intense focused spot is essential for reliable production results. This paper presents a focal spot analyser that is developed...

  3. Mass Equivalent Pantographs for Synthesis of Balanced Focal Mechanisms

    NARCIS (Netherlands)

    van der Wijk, V.; Lenarcic, Jadran; Merlet, Jean-Pierre

    2016-01-01

    Force balance is an important property in the design of high-speed high precision machinery to reduce base vibrations and also for the design of inherently safe large movable structures. This paper presents the synthesis of inherently balanced overconstrained focal mechanisms with mass equivalent

  4. A 1.3 giga pixels focal plane for GAIA

    Science.gov (United States)

    Laborie, Anouk; Pouny, Pierre; Vetel, Cyril; Collados, Emmanuel; Rougier, Gilles; Davancens, Robert; Zayer, Igor; Perryman, Michael; Pace, Oscar

    2004-06-01

    The astrometric mission GAIA is a cornerstone mission of the European Space Agency, due for launch in the 2010 time frame. Requiring extremely demanding performance GAIA calls for the development of an unprecedented large focal plane featuring innovative technologies. For securing the very challenging GAIA development, a significant number of technology activities have been initiated by ESA through a competitive selection process. In this context, an industrial consortium led by EADS-Astrium (France) with e2v technologies (UK) as major subcontractor was selected for the GAIA CCD and Focal Plane Technology Demonstrators programme, which is by far the most significant and the most critical GAIA pre-development for all aspects: science performance, development schedule and cost. This programme has started since August 2002 and will end early 2005 prior to commencement of the GAIA Phase B. While the GAIA payload will host three instruments and related focal planes, the major mission objectives are assigned to the Astrometric (ASTRO) Focal Plane, which is the subject of this presentation.

  5. A case of pathological rib fractures: focal osteolysis or osteoporosis?

    Science.gov (United States)

    Vrbanić, T S L; Novak, S; Sestan, B; Tudor, A; Gulan, G

    2008-03-01

    This paper reports on a unique, previously unreported, successful outcome in the case of a patient with focal osteolytic lesions of the ribs as a first sign of osteoporosis. The lesions were detected by chance after acute cough-induced rib fractures were seen on plain chest radiographs. The diagnosis had to be approached as a diagnosis of exclusion since known causes of the osteolytic process had to be eliminated. The authors describe multiple focal osteolytic lesions with rib fractures appearing in a pattern that could be confused with metastases. Laboratory results were normal. Final diagnosis was based on plain radiography, bone scan and bone densitometry. Pharmacomedical treatments for osteoporosis were applied. The patient was observed between the year 2000 and 2005. Five years later radiological and bone scintigraphy revealed resolution of the lesion. We conclude that osteoporosis should be included in the differential diagnosis of asymptomatic focal osteolysis of the ribs with rib fractures as a complication of acute cough. The case suggests that focal osteolytic lesions of the ribs may regress over time and become scintigraphically inactive.

  6. Shared Focal Plane Investigation for Serial Frame Cameras.

    Science.gov (United States)

    1980-03-01

    capability will be restored. 41. -.. TrABLE 1-1 SYSTEM LEADING P) ARTICULARS Lens Focal Length (inches) Range (ft) Contrast 12 18 24 Coverage 22.1...can be expected that signature bands will be apparent in the imagery. Such bands are at best distracting and at worst hindrances to image interpretation

  7. Tratamento focal e perifocal contra Aëdes aegypti

    Directory of Open Access Journals (Sweden)

    Milton Moura Lima

    1987-06-01

    Full Text Available Em quatro bairros da cidade do Rio de Janeiro, foram feitos ensaios de tratamento focal com abate granulado a 1 ppm e perifocal com pó molhável de Sumition a 2,5%. Esses tratamentos foram feitos tanto isoladamente quanto em conjunto e, também, associados à aplicação de inseticida a ultrabaixo volume. Os índices prediais, levantados um mês depois de terminado o trabalho, mostraram que o tratamento focal dispensa qualquer medida auxiliar. O tratamento perifocal mostrou-se inócuo e incapaz de impedir o aparecimento de larvas de Aëdes aegypti e de outros insetos, em pneus pintados, na face externa, com Sumition e com Malation.In four districts of the city of Rio dc Janeiro focal treatment essays with granulated Abate at 1 ppm and perifocal treatment essays with wettable powder of Sumithion at 2,5% were performed. These were made either alone or in combination as well as associated to insecticides applied at ultra low volume. The premise indices obtained one month after the treatments indicates that the focal treatment alone is effective, no other addicional methods being necessary. The perifocal treatment is not effective and did not prevent the development of Aedes aegypti larvae and other insects in tires which had their external surface painted with Sumithion and Malathion.

  8. Axial and focal-plane diffraction catastrophe integrals

    International Nuclear Information System (INIS)

    Berry, M V; Howls, C J

    2010-01-01

    Exact expressions in terms of Bessel functions are found for some of the diffraction catastrophe integrals that decorate caustics in optics and mechanics. These are the axial and focal-plane sections of the elliptic and hyperbolic umbilic diffraction catastrophes, and symmetric elliptic and hyperbolic unfoldings of the X 9 diffraction catastrophes. These representations reveal unexpected relations between the integrals.

  9. Neurophysiological evidence for cerebellar dysfunction in primary focal dystonia.

    NARCIS (Netherlands)

    Teo, J.T.; Warrenburg, B.P.C. van de; Schneider, S.A.; Rothwell, J.C.; Bhatia, K.P.

    2009-01-01

    Recent studies have suggested that there may be functional and structural changes in the cerebellum of patients with adult onset primary focal dystonia. The aim of this study was to establish whether there is any neurophysiological indicator of abnormal cerebellar function, using the classic

  10. The Localizing Value Of Focal Delta Slowing In Temporal Lobe ...

    African Journals Online (AJOL)

    Slow wave EEG had a higher marginal probability than neuropsychological assessment of predicting the focus, and was equally effective as other investigative methods. Conclusion These results suggest that focal temporal delta slowing is useful in the localization of epileptogenic foci. There was no discordance with the ...

  11. Management of HIV-associated focal brain lesions in developing ...

    African Journals Online (AJOL)

    Background. HIV-associated focal brain lesions (FBLs) are caused by opportunistic infections, neoplasms, or cerebrovascular diseases. In developed countries toxoplasma encephalitis (TE) is the most frequent cause followed by primary CNS lymphoma (PCNSL). Guidelines based on these causes have been proposed ...

  12. Quantum-Well Infrared Photodetector (QWIP) Focal Plane Assembly

    Science.gov (United States)

    Jhabvala, Murzy; Jhabvala, Christine A.; Ewin, Audrey J.; Hess, Larry A.; Hartmann, Thomas M.; La, Anh T.

    2012-01-01

    A paper describes the Thermal Infrared Sensor (TIRS), a QWIP-based instrument intended to supplement the Operational Land Imager (OLI) for the Landsat Data Continuity Mission (LDCM). The TIRS instrument is a far-infrared imager operating in the pushbroom mode with two IR channels: 10.8 and 12 microns. The focal plane will contain three 640x512 QWIP arrays mounted on a silicon substrate. The silicon substrate is a custom-fabricated carrier board with a single layer of aluminum interconnects. The general fabrication process starts with a 4-in. (approx.10-cm) diameter silicon wafer. The wafer is oxidized, a single substrate contact is etched, and aluminum is deposited, patterned, and alloyed. This technology development is aimed at incorporating three large-format infrared detecting arrays based on GaAs QWIP technology onto a common focal plane with precision alignment of all three arrays. This focal plane must survive the rigors of flight qualification and operate at a temperature of 43 K (-230 C) for five years while orbiting the Earth. The challenges presented include ensuring thermal compatibility among all the components, designing and building a compact, somewhat modular system and ensuring alignment to very tight levels. The multi-array focal plane integrated onto a single silicon substrate is a new application of both QWIP array development and silicon wafer scale integration. The Invar-based assembly has been tested to ensure thermal reliability.

  13. [Primary focal dystonia: descriptive study of 205 patients].

    Science.gov (United States)

    Bartolomé, F M; Fanjul, S; Cantarero, S; Hernández, J; García Ruiz, P J

    2003-03-01

    To describe the clinical and epidemiologic aspects of different types of focal dystonia. A total of 205 patients with primary focal dystonia were studied retrospectively and the following variables were analyzed: gender, age of onset, age at examination, evolution time, history of trauma, association with other movement disorders, fluctuations of dystonic symptoms as well as a family history of dystonia, Parkinson's disease, tremor, and lefthandedness or stuttering. We compared these variables among the different clinical categories of focal dystonia. Those patients with cranial and laryngeal dystonia were significantly older at the onset of symptoms compared with patients with writer's cramp. Males were more prevalent than females in all categories of focal dystonia except for cranial dystonia. Prior history of trauma and association with tremor were more frequent in patients with cervical dystonia than in those with others dystonic categories. Most patients with cranial, cervical and laryngeal dystonia had fluctuations in the intensity of dystonic symptoms, unlike the patients with writer's cramp. There is a caudo-cranial gradient in age of onset and the age of onset increases as the cranial presentation becomes greater. Females are more prevalent in cranial dystonia and there is a preponderance of males in the dystonias with a lower location. The dystonias with cranial distribution frequently present fluctuations of symptoms during the day. Association with other movement disorders, such as tremor, and prior history of trauma, is common in patients with cervical dystonia.

  14. Focal fibrocartilaginous dysplasia and tibia vara: a case report

    International Nuclear Information System (INIS)

    Cockshott, W.P.; Martin, R.; Friedman, L.; Yuen, M.

    1994-01-01

    A 2-year-old black boy with focal fibrocartilaginous dysplasia is described with illustrations of the typical radiographic appearances supplemented by computed tomographic and magnetic resonance images. Since this rare condition is self-correcting, diagnosis is important so that surgical intervention and biopsy can be avoided and conservative management instituted. (orig.)

  15. Focal fibrocartilaginous dysplasia and tibia vara: a case report.

    Science.gov (United States)

    Cockshott, W P; Martin, R; Friedman, L; Yuen, M

    1994-07-01

    A 2-year-old black boy with focal fibrocartilaginous dysplasia is described with illustrations of the typical radiographic appearances supplemented by computed tomographic and magnetic resonance images. Since this rare condition is self-correcting, diagnosis is important so that surgical intervention and biopsy can be avoided and conservative management instituted.

  16. Focal fibrocartilaginous dysplasia and tibia vara: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Cockshott, W.P. (Dept. of Radiology, McMaster Univ. Medical Centre, Hamilton, ON (Canada)); Martin, R. (Dept. of Orthopedics, McMaster Univ. Medical Centre, Hamilton, ON (Canada)); Friedman, L. (Dept. of Radiology, McMaster Univ. Medical Centre, Hamilton, ON (Canada)); Yuen, M. (Dept. of Radiology, McMaster Univ. Medical Centre, Hamilton, ON (Canada))

    1994-07-01

    A 2-year-old black boy with focal fibrocartilaginous dysplasia is described with illustrations of the typical radiographic appearances supplemented by computed tomographic and magnetic resonance images. Since this rare condition is self-correcting, diagnosis is important so that surgical intervention and biopsy can be avoided and conservative management instituted. (orig.)

  17. Contrast enhanced ultrasound in CT-undetermined focal liver lesions

    DEFF Research Database (Denmark)

    Sandrose, Sebastian; Karstrup, S.; Gerke, Oke

    2016-01-01

    , surgical resection, PET/CT and clinical follow-up. Results: The 78 included patients had 163 undetermined focal liver lesions, mean size 1.1 cm, range 0.1–5.3 cm. There were 18 malignant and 145 benign liver lesions, as defined by the standard of reference. In differentiating between benign vs. malignant...

  18. Automatic test comes to focal plane array production

    Science.gov (United States)

    Skaggs, Frank L.; Barton, T. D.

    1992-08-01

    To meet the needs of military and commercial markets, the infrared focal plane array industry must develop new, effective and low cost methods of fabricating and testing imaging detectors. This paper describes Texas Instruments new concepts in automated testing and cold probe technology as they apply to volume production.

  19. Focal irreversible electroporation as primary treatment for localized prostate cancer

    NARCIS (Netherlands)

    van den Bos, Willemien; Scheltema, Matthijs J.; Siriwardana, Amila R.; Kalsbeek, Anton M. F.; Thompson, James E.; Ting, Francis; Böhm, Maret; Haynes, Anne-Maree; Shnier, Ron; Delprado, Warick; Stricker, Phillip D.

    2017-01-01

    To determine the safety, quality of life (QoL) and short-term oncological outcomes of primary focal IRE for the treatment of localized prostate cancer. To identify potential risk factors for oncological failure. Patients that met both the consensus guidelines on patient criteria and selection

  20. Position sensitive proportional counters as focal plane detectors

    International Nuclear Information System (INIS)

    Ford, J.L.C. Jr.

    1979-01-01

    The rise time and charge division techniques for position decoding with RC-line proportional counters are reviewed. The advantages that these detectors offer as focal plane counters for nuclear spectroscopy performed with magnetic spectrographs are discussed. The theory of operation of proportional counters as position sensing devices is summarized, as well as practical aspects affecting their application. Factors limiting the position and energy resolutions obtainable with a focal plane proportional counter are evaluated and measured position and energy loss values are presented for comparison. Detector systems capable of the multiparameter measurements required for particle identification, background suppression and ray-tracing are described in order to illustrate the wide applicability of proportional counters within complex focal plane systems. Examples of the use of these counters other than with magnetic spectrographs are given in order to demonstrate their usefulness in not only nuclear physics but also in fields such as solid state physics, biology, and medicine. The influence of the new focal plane detector systems on future magnetic spectrograph designs is discussed. (Auth.)

  1. White matter integrity and cerebral network topology in focal epilepsy

    NARCIS (Netherlands)

    Otte, W.M.

    2012-01-01

    Worldwide more than fifty million people suffer from recurrent spontaneous seizures. Seizures are considered to be harmful to the brain and may have adverse long-term behavioral and cognitive consequences in particular in people with focal epilepsies that do not respond to pharmacotherapy.

  2. Mutations in KCNT1 cause a spectrum of focal epilepsies

    Science.gov (United States)

    Møller, Rikke S.; Heron, Sarah E.; Larsen, Line H. G.; Lim, Chiao Xin; Ricos, Michael G.; Bayly, Marta A.; van Kempen, Marjan J. A.; Klinkenberg, Sylvia; Andrews, Ian; Kelley, Kent; Ronen, Gabriel M.; Callen, David; McMahon, Jacinta M.; Yendle, Simone C.; Carvill, Gemma L.; Mefford, Heather C.; Nabbout, Rima; Poduri, Annapurna; Striano, Pasquale; Baglietto, Maria G.; Zara, Federico; Smith, Nicholas J.; Pridmore, Clair; Gardella, Elena; Nikanorova, Marina; Dahl, Hans Atli; Gellert, Pia; Scheffer, Ingrid E.; Gunning, Boudewijn; Kragh-Olsen, Bente; Dibbens, Leanne M.

    2018-01-01

    Summary Autosomal dominant mutations in the sodium-gated potassium channel subunit gene KCNT1 have been associated with two distinct seizure syndromes, nocturnal frontal lobe epilepsy (NFLE) and malignant migrating focal seizures of infancy (MMFSI). To further explore the phenotypic spectrum associated with KCNT1, we examined individuals affected with focal epilepsy or an epileptic encephalopathy for mutations in the gene. We identified KCNT1 mutations in 12 previously unreported patients with focal epilepsy, multifocal epilepsy, cardiac arrhythmia, and in a family with sudden unexpected death in epilepsy (SUDEP), in addition to patients with NFLE and MMFSI. In contrast to the 100% penetrance so far reported for KCNT1 mutations, we observed incomplete penetrance. It is notable that we report that the one KCNT1 mutation, p.Arg398Gln, can lead to either of the two distinct phenotypes, ADNFLE or MMFSI, even within the same family. This indicates that genotype–phenotype relationships for KCNT1 mutations are not straightforward. We demonstrate that KCNT1 mutations are highly pleiotropic and are associated with phenotypes other than ADNFLE and MMFSI. KCNT1 mutations are now associated with Ohtahara syndrome, MMFSI, and nocturnal focal epilepsy. They may also be associated with multifocal epilepsy and cardiac disturbances. PMID:26122718

  3. Differential diagnosis of focal pancreatitis and pancreatic cancer

    NARCIS (Netherlands)

    van Gulik, T. M.; Moojen, T. M.; van Geenen, R.; Rauws, E. A.; Obertop, H.; Gouma, D. J.

    1999-01-01

    The differentiation of focal, chronic pancreatitis (CP) and pancreatic cancer (PAC) poses a diagnostic dilemma. Both conditions may present with the same symptoms and signs. The complexity of differential diagnosis is enhanced because PAC is frequently associated with secondary inflammatory changes

  4. Mutations in KCNT1 cause a spectrum of focal epilepsies

    DEFF Research Database (Denmark)

    Møller, Rikke Steensbjerre; Heron, Sarah E.; Larsen, Line H. G.

    2015-01-01

    Autosomal dominant mutations in the sodium-gated potassium channel subunit gene KCNT1 have been associated with two distinct seizure syndromes, nocturnal frontal lobe epilepsy (NFLE) and malignant migrating focal seizures of infancy (MMFSI). To further explore the phenotypic spectrum associated w...

  5. Dosimetry Modeling for Focal Low-Dose-Rate Prostate Brachytherapy

    Energy Technology Data Exchange (ETDEWEB)

    Al-Qaisieh, Bashar [Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds (United Kingdom); Mason, Josh, E-mail: joshua.mason@nhs.net [Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds (United Kingdom); Bownes, Peter; Henry, Ann [Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds (United Kingdom); Dickinson, Louise [Division of Surgery and Interventional Science, University College London, London (United Kingdom); Department of Radiology, Northwick Park Hospital, London North West NHS Trust, London (United Kingdom); Ahmed, Hashim U. [Division of Surgery and Interventional Science, University College London, London (United Kingdom); University College London Hospital, London (United Kingdom); Emberton, Mark [University College London Hospital, London (United Kingdom); Langley, Stephen [St Luke' s Cancer Centre, Guildford (United Kingdom)

    2015-07-15

    Purpose: Focal brachytherapy targeted to an individual lesion(s) within the prostate may reduce side effects experienced with whole-gland brachytherapy. The outcomes of a consensus meeting on focal prostate brachytherapy were used to investigate optimal dosimetry of focal low-dose-rate (LDR) prostate brachytherapy targeted using multiparametric magnetic resonance imaging (mp-MRI) and transperineal template prostate mapping (TPM) biopsy, including the effects of random and systematic seed displacements and interseed attenuation (ISA). Methods and Materials: Nine patients were selected according to clinical characteristics and concordance of TPM and mp-MRI. Retrospectively, 3 treatment plans were analyzed for each case: whole-gland (WG), hemi-gland (hemi), and ultra-focal (UF) plans, with 145-Gy prescription dose and identical dose constraints for each plan. Plan robustness to seed displacement and ISA were assessed using Monte Carlo simulations. Results: WG plans used a mean 28 needles and 81 seeds, hemi plans used 17 needles and 56 seeds, and UF plans used 12 needles and 25 seeds. Mean D90 (minimum dose received by 90% of the target) and V100 (percentage of the target that receives 100% dose) values were 181.3 Gy and 99.8% for the prostate in WG plans, 195.7 Gy and 97.8% for the hemi-prostate in hemi plans, and 218.3 Gy and 99.8% for the focal target in UF plans. Mean urethra D10 was 205.9 Gy, 191.4 Gy, and 92.4 Gy in WG, hemi, and UF plans, respectively. Mean rectum D2 cm{sup 3} was 107.5 Gy, 77.0 Gy, and 42.7 Gy in WG, hemi, and UF plans, respectively. Focal plans were more sensitive to seed displacement errors: random shifts with a standard deviation of 4 mm reduced mean target D90 by 14.0%, 20.5%, and 32.0% for WG, hemi, and UF plans, respectively. ISA has a similar impact on dose-volume histogram parameters for all plan types. Conclusions: Treatment planning for focal LDR brachytherapy is feasible. Dose constraints are easily met with a notable

  6. METHOD FOR DETERMINATION OF FOCAL PLANE LOCATION OF FOCUSING COMPONENTS

    Directory of Open Access Journals (Sweden)

    A. I. Ivashko

    2017-01-01

    Full Text Available Mass-production of different laser systems often requires utilization of the focal spot size method for determination of output laser beam spatial characteristics. The main challenge of this method is high accuracy maintenance of a CCD camera beam profiler in the collecting lens focal plane. The aim of our work is development of new method for placing of photodetector array in the collecting lens focal plane with high accuracy.Proposed technique is based on focusing of several parallel laser beams. Determination of the focal plane position requires only longitudinal translation of the CCD-camera to find a point of laser beams intersection. Continuous-wave (CW diode-pumped laser emitting in the spectral region near 1μm was created to satisfy the requirements of the developed technique. Designed microchip laser generates two stigmatic Gaussian beams with automatically parallel beam axes due to independent pumping of different areas of the one microchip crystal having the same cavity mirrors.It was theoretically demonstrated that developed method provides possibility of the lenses focal plane determination with 1 % accuracy. The microchip laser generates two parallel Gaussian beams with divergence of about 10 mrad. Laser output power can be varied in the range of 0.1–1.5 W by changing the pumping laser diode electrical current. The distance between two beam axes can be changed in the range of 0.5–5.0 mm.We have proposed method for determination of positive lens focal plane location by using of CCDcamera and two laser beams with parallel axes without utilization of additional optical devices. We have developed CW longitudinally diode pumped microchip laser emitting in the 1-μm spectral region that can be used in the measuring instrument that doesn’t require precision mechanical components for determination of focal plane location with 1 % accuracy. The overall dimensions of laser head was 70 × 40 × 40 mm3 and maximum power consumption was

  7. Context cue focality influences strategic prospective memory monitoring.

    Science.gov (United States)

    Hunter Ball, B; Bugg, Julie M

    2018-02-12

    Monitoring the environment for the occurrence of prospective memory (PM) targets is a resource-demanding process that produces cost (e.g., slower responding) to ongoing activities. However, research suggests that individuals are able to monitor strategically by using contextual cues to reduce monitoring in contexts in which PM targets are not expected to occur. In the current study, we investigated the processes supporting context identification (i.e., determining whether or not the context is appropriate for monitoring) by testing the context cue focality hypothesis. This hypothesis predicts that the ability to monitor strategically depends on whether the ongoing task orients attention to the contextual cues that are available to guide monitoring. In Experiment 1, participants performed an ongoing lexical decision task and were told that PM targets (TOR syllable) would only occur in word trials (focal context cue condition) or in items starting with consonants (nonfocal context cue condition). In Experiment 2, participants performed an ongoing first letter judgment (consonant/vowel) task and were told that PM targets would only occur in items starting with consonants (focal context cue condition) or in word trials (nonfocal context cue condition). Consistent with the context cue focality hypothesis, strategic monitoring was only observed during focal context cue conditions in which the type of ongoing task processing automatically oriented attention to the relevant features of the contextual cue. These findings suggest that strategic monitoring is dependent on limited-capacity processing resources and may be relatively limited when the attentional demands of context identification are sufficiently high.

  8. Flotillins Regulate Focal Adhesions by Interacting with α-Actinin and by Influencing the Activation of Focal Adhesion Kinase

    Directory of Open Access Journals (Sweden)

    Antje Banning

    2018-04-01

    Full Text Available Cell–matrix adhesion and cell migration are physiologically important processes that also play a major role in cancer spreading. In cultured cells, matrix adhesion depends on integrin-containing contacts such as focal adhesions. Flotillin-1 and flotillin-2 are frequently overexpressed in cancers and are associated with poor survival. Our previous studies have revealed a role for flotillin-2 in cell–matrix adhesion and in the regulation of the actin cytoskeleton. We here show that flotillins are important for cell migration in a wound healing assay and influence the morphology and dynamics of focal adhesions. Furthermore, anchorage-independent growth in soft agar is enhanced by flotillins. In the absence of flotillins, especially flotillin-2, phosphorylation of focal adhesion kinase and extracellularly regulated kinase is diminished. Flotillins interact with α-actinin, a major regulator of focal adhesion dynamics. These findings are important for understanding the molecular mechanisms of how flotillin overexpression in cancers may affect cell migration and, especially, enhance metastasis formation.

  9. Seismic sequences and swarms in the Latium-Abruzzo-Molise Apennines (central Italy): New observations and analysis from a dense monitoring of the recent activity

    Science.gov (United States)

    Frepoli, A.; Cimini, G. B.; De Gori, P.; De Luca, G.; Marchetti, A.; Monna, S.; Montuori, C.; Pagliuca, N. M.

    2017-08-01

    We present a detailed analysis of the seismic activity in the central Apennines based on a high quality seismogram data set collected from two temporary and three permanent networks. This integrated network recorded, between January 2009 and December 2013, a total of 7011 local earthquakes (6270 selected for this study), with local magnitudes ML ranging from 0.4 to 4.7. Hypocentres were located by using a reference 1D crustal velocity model determined with a genetic algorithm. The majority of the hypocenters are located beneath the axis of the Apenninic belt, while the rest are found along the peri-Tyrrhenian margin. Hypocentral depth distribution extends to a depth of 31 km with a pronounced peak between 8 and 12 km. Both low-to-moderate magnitude seismic sequences and diffuse swarm-like seismicity was observed. There were two major seismic swarms and a seismic sequence, which included the Marsica-Sora ML 4.7 main shock. A total of 468 fault plane solutions were derived from P-wave polarities. This new data set more than quadruples the number of focal mechanisms that was previously available for regional stress field analysis in the study region. The majority of the fault plane solutions in the central Apennines show predominantly normal fault movements, with T-axis trends oriented NE-SW. Focal mechanisms calculated in this study confirm that this area is in extension. For the seismic swarms-sequence in the Marsica-Sora area we also derived the azimuth and plunge of the principal stress axes by inverting fault plane solutions. We find a few right-lateral strike-slip focal mechanisms that possibly identify the prolongation of the strike-slip kinematics in the Gargano-Apulia foreland to the west, and mark the passage to the NW-SE striking normal faults of the inner Apenninic belt. The seismicity and stress distribution we observe might be consistent with a fragmented tectonic scenario in which faults with small dimensions release seismic energy in a diffused way.

  10. The 1992 Tafilalt seismic crisis (Anti-Atlas, Morocco)

    Science.gov (United States)

    Bensaid, Ihsane; Cherkaoui, Taj-Eddine; Medina, Fida; Caldeira, Bento; Buforn, Elisa; Emran, Anas; Hahou, Youssef

    2012-01-01

    The Tafilalt region, located at the eastern end of the Anti-Atlas chain in Morocco, was shaken on 23 and 30 October 1992 by two moderate earthquakes of magnitude mb ˜ 5 and intensity ˜ VI MSK64, which caused two deaths and great damage in the area between Erfoud and Rissani. The review of data available on the seismic crisis allowed us to improve the knowledge on the macroseismic, instrumental and source parameters of the earthquakes. The main results of the present study are: (1) location of the epicentres with the help of data from a close portable network allowed us to propose new epicentral coordinates at 31.361° N, 4.182° W (23 October) and 31.286° N, 4.347° W (30 October); both events have focal depths of 2 km; (2) the shock of 30 October was followed by a series of 305 aftershocks, most of which were located west of Rissani; the 61 best-constrained events had focal depths of 5 to 19 km and magnitudes 0.7 to 3; (3) the largest damage was located in an area between the two epicentres within the Tafilalt valley and was probably amplified by site effects due to the proximity of the water table within the Quaternary sediments; (4) focal mechanisms of the main events correspond to strike-slip faulting with fault planes oriented N-S (left lateral) and E-W (right lateral); the only mechanism available for the aftershocks also corresponds to strike-slip faulting; (5) spectral analysis shows that the scalar seismic moment ( Mo) of the first event is slightly larger than the second; the corresponding values of Mw are 5.1 and 5.0, respectively; (6) the dimensions of the faults for a circular fault model are 7.7 ± 1.4 and 7.4 ± 1.2 km, respectively; the average displacement is 4 cm for the first event and 3.7 cm for the second; the stress drop is 0.4 and 0.3 MPa, respectively, in agreement with standard values; (7) the Coulomb Stress test performed for both earthquakes suggests a relationship between both events only when the used location is at the limit of the

  11. The flexible engagement of monitoring processes in non-focal and focal prospective memory tasks with salient cues.

    Science.gov (United States)

    Hefer, Carmen; Cohen, Anna-Lisa; Jaudas, Alexander; Dreisbach, Gesine

    2017-09-01

    Prospective memory (PM) refers to the ability to remember to perform a delayed intention. Here, we aimed to investigate the ability to suspend such an intention and thus to confirm previous findings (Cohen, Gordon, Jaudas, Hefer, & Dreisbach, 2016) demonstrating the ability to flexibly engage in monitoring processes. In the current study, we presented a perceptually salient PM cue (bold and red) to rule out that previous findings were limited to non-salient and, thus, easy to ignore PM cues. Moreover, we used both a non-focal (Experiment 1) and a focal PM (Experiment 2) cue. In both Experiments, three groups of participants performed an Eriksen flanker task as an ongoing task with an embedded PM task (they had to remember to press the F1 key if a pre-specified cue appeared). Participants were assigned to either a control condition (performed solely the flanker task), a standard PM condition (performed the flanker task along with the PM task), or a PM delayed condition (performed the flanker task but were instructed to postpone their PM task intention). The results of Experiment 1 with the non-focal PM cue closely replicated those of Cohen et al. (2016) and confirmed that participants were able to successfully postpone the PM cue intention without additional costs even when the PM cue was a perceptually salient one. However, when the PM cue was focal (Experiment 2), it was much more difficult for participants to ignore it as evidenced by commission errors and slower latencies on PM cue trials. In sum, results showed that the focality of the PM cue plays a more crucial role in the flexibility of the monitoring process whereas the saliency of the PM cue does not. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Natural-focal diseases: mapping experience in Russia.

    Science.gov (United States)

    Malkhazova, Svetlana M; Mironova, Varvara A; Kotova, Tatiana V; Shartova, Natalia V; Orlov, Dmitry S

    2014-06-14

    Natural-focal diseases constitute a serious hazard for human health. Agents and vectors of such diseases belong to natural landscapes. The aim of this study is to identify the diversity and geography of natural-focal diseases in Russia and to develop cartographic approaches for their mapping, including mathematical-cartographical modeling. Russian medico-geographical mapping of natural-focal diseases is highly developed regionally and locally but extremely limited at the national level. To solve this problem, a scientific team of the Faculty of Geography at Lomonosov Moscow State University has developed and implemented a project of a medico-geographical Atlas of Russia "Natural-Focal Diseases". The mapping is based on medical statistics data. The Atlas contains a series of maps on disease incidence, long-term dynamics of disease morbidity, etc. In addition, other materials available to the authors were used: mapping of the natural environment, field data, archival materials, analyzed satellite images, etc. The maps are processed using ArcGIS (ESRI) software application. Different methods of rendering of mapped phenomena are used (geographical ranges, diagrams, choropleth maps etc.). A series of analytical, integrated, and synthetic maps shows disease incidence in the population at both the national and regional levels for the last 15 years. Maps of the mean annual morbidity of certain infections and maps of morbidity dynamics and nosological profiles allow for a detailed analysis of the situation for each of 83 administrative units of the Russian Federation. The degree of epidemic hazard in Russia by natural-focal diseases is reflected in a synthetic medico-geographical map that shows the degree of epidemic risks due to such diseases in Russia and allows one to estimate the risk of disease manifestation in a given region. This is the first attempt at aggregation and public presentation of diverse and multifaceted information about natural-focal diseases in Russia

  13. CT and ERCP findings of chronic focal pancreatitis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hee Soo; Lee, Jong Tae; Yoo, Hyung Sik; Kim, Eun Kyeong [Yonsei Univ. College of Medicine, Seoul (Korea, Republic of)

    1996-10-01

    To evaluate the major radiologic features of chronic focal pancreatitis in various imaging studies, with special emphasis on CT and ERCP findings. From 1991 to 1995, twelve patients were pathologically proved to be suffering from focal chronic pancreatitis after pancreatico-duodenectomy;for retrospective evaluation, imaging studies were available for eight(seven men, one woman;mean age 58.9{+-}6.6, range 47 to 67). Clinical, surgical, and radiological findings, including CT(n=8), ultrasound(n=7), ERCP(n=8) and UGI(n=3) were analysed. Seven male patients had suffered from chronic alcoholism for between 20 and 50 years. Serum bilirubin levels were normal in eight patients and alkaline phosphatase levels were normal in seven patients. Serum CA 19-9 levels were normal in all five patients who had undergone preoperative evaluation. Seven patients(87.5%) showed focal enlargement without definable margin on CT, and five of the six lesions detectable on ultrasound(83.3%) were ill defined hypoechoic nodules. Dilated side branches within lesions were seen in five of eight patients(83.3%) on CT and ERCP. Double duct signs were observed in siven(87.5%) patients, and dilated intrahepatic ducts in six(75%), with diameters ranging from 5 to 8mm(average:5.42{+-}1.96mm). The average ratio of pancreatic duct caliber to gland width was 0.33{+-}0.19. None of the patients had calcification within the lesion and one case showed intraductal calcification. None showed perivascular fat obliteration around the superior mesenteric artery or celiac axis. The average biductal distance between abnormal common bile duct and the immediately adjacent pancreatic duct was 4.0{+-}1.15mm. One of three cases who under went a UGI examination showed severe luminal narrowing and mucosal thickening in the second protion of the duodenum, another showed double contour, and the other merely showed widening of the C-loop of the duodenum. Chronic focal pancreatitis mostly demonstrated ill defined focal

  14. CT and ERCP findings of chronic focal pancreatitis

    International Nuclear Information System (INIS)

    Kim, Hee Soo; Lee, Jong Tae; Yoo, Hyung Sik; Kim, Eun Kyeong

    1996-01-01

    To evaluate the major radiologic features of chronic focal pancreatitis in various imaging studies, with special emphasis on CT and ERCP findings. From 1991 to 1995, twelve patients were pathologically proved to be suffering from focal chronic pancreatitis after pancreatico-duodenectomy;for retrospective evaluation, imaging studies were available for eight(seven men, one woman;mean age 58.9±6.6, range 47 to 67). Clinical, surgical, and radiological findings, including CT(n=8), ultrasound(n=7), ERCP(n=8) and UGI(n=3) were analysed. Seven male patients had suffered from chronic alcoholism for between 20 and 50 years. Serum bilirubin levels were normal in eight patients and alkaline phosphatase levels were normal in seven patients. Serum CA 19-9 levels were normal in all five patients who had undergone preoperative evaluation. Seven patients(87.5%) showed focal enlargement without definable margin on CT, and five of the six lesions detectable on ultrasound(83.3%) were ill defined hypoechoic nodules. Dilated side branches within lesions were seen in five of eight patients(83.3%) on CT and ERCP. Double duct signs were observed in siven(87.5%) patients, and dilated intrahepatic ducts in six(75%), with diameters ranging from 5 to 8mm(average:5.42±1.96mm). The average ratio of pancreatic duct caliber to gland width was 0.33±0.19. None of the patients had calcification within the lesion and one case showed intraductal calcification. None showed perivascular fat obliteration around the superior mesenteric artery or celiac axis. The average biductal distance between abnormal common bile duct and the immediately adjacent pancreatic duct was 4.0±1.15mm. One of three cases who under went a UGI examination showed severe luminal narrowing and mucosal thickening in the second protion of the duodenum, another showed double contour, and the other merely showed widening of the C-loop of the duodenum. Chronic focal pancreatitis mostly demonstrated ill defined focal enlargement and

  15. Stress Transfer Processes during Great Plate Boundary Thrusting Events: A Study from the Andaman and Nicobar Segments

    Science.gov (United States)

    Andrade, V.; Rajendran, K.

    2010-12-01

    Diglipur (depth: 21 km) and the August 10, 2009, Mw 7.5 normal faulting earthquake near Coco Island (depth: 22 km), within the northern terminus of the 2004 rupture are cited as examples of the alternating pre and post earthquake stress conditions. The major pre and post 2004 clusters were associated with the Andaman Spreading Ridge (ASR). In the Nicobar segment, the most recent earthquake on June 12, 2010, Mw 7.5 (focal depth: 35 km) occurred very close to the plate boundary, through left lateral strike-slip faulting. A segment that does not feature any active volcanoes unlike its northern and southern counterparts, this part of the plate boundary has generated several right lateral strike-slip earthquakes, mostly on the Sumatra Fault System. The left-lateral strike-slip faulting associated with the June 12 event on a nearly N-S oriented fault plane consistent with the trend of the Ninety East ridge and the occasional left-lateral earthquakes prior to the 2004 mega-thrust event suggest the involvement of the Ninety East ridge in the subduction process.

  16. Oral focal epithelial hyperplasia: report of three cases.

    Science.gov (United States)

    Ghalayani, Parichehr; Tavakoli, Payam; Eftekhari, Mehdi; Haghighi, Mohammad Akhondzadeh

    2015-01-01

    Focal epithelial hyperplasia or Heck's disease is an infrequent asymptomatic condition caused by human papillomavirus types 13 or 32 affecting the mucous membrane of the mouth and is commonly seen in young individuals. Firstly, it was described in Indians and Eskimos, but it exists in various populations. We present three cases of Heck's disease in an Afghan immigrant family group living in Iran that seem to have familial predominance. The disease was identified as oral focal epithelial hyperplasia on the basis of histopathologic and clinical findings. The lesions were reduced significantly after 4 months of good oral hygiene. Dentists should be familiar with the clinical manifestations of these types of lesions that affect the oral cavity. In fact, histopathologic assessment and clinical observation are necessary to establish the diagnosis.

  17. Uncooled infrared focal plane array imaging in China

    Science.gov (United States)

    Lei, Shuyu

    2015-06-01

    This article reviews the development of uncooled infrared focal plane array (UIFPA) imaging in China in the past decade. Sensors based on optical or electrical read-out mechanism were developed but the latter dominates the market. In resistive bolometers, VOx and amorphous silicon are still the two major thermal-sensing materials. The specifications of the IRFPA made by different manufactures were collected and compared. Currently more than five Chinese companies and institutions design and fabricate uncooled infrared focal plane array. Some devices have sensitivity as high as 30 mK; the largest array for commercial products is 640×512 and the smallest pixel size is 17 μm. Emphasis is given on the pixel MEMS design, ROIC design, fabrication, and packaging of the IRFPA manufactured by GWIC, especially on design for high sensitivities, low noise, better uniformity and linearity, better stabilization for whole working temperature range, full-digital design, etc.

  18. Focal points and principal solutions of linear Hamiltonian systems revisited

    Science.gov (United States)

    Šepitka, Peter; Šimon Hilscher, Roman

    2018-05-01

    In this paper we present a novel view on the principal (and antiprincipal) solutions of linear Hamiltonian systems, as well as on the focal points of their conjoined bases. We present a new and unified theory of principal (and antiprincipal) solutions at a finite point and at infinity, and apply it to obtain new representation of the multiplicities of right and left proper focal points of conjoined bases. We show that these multiplicities can be characterized by the abnormality of the system in a neighborhood of the given point and by the rank of the associated T-matrix from the theory of principal (and antiprincipal) solutions. We also derive some additional important results concerning the representation of T-matrices and associated normalized conjoined bases. The results in this paper are new even for completely controllable linear Hamiltonian systems. We also discuss other potential applications of our main results, in particular in the singular Sturmian theory.

  19. Focal sparing around the gallbladder in fatty liver

    International Nuclear Information System (INIS)

    Chen, Kemin; Hiramatsu, Yoshihiro; Yunoki, Masanori; Hirano, Yoko

    1989-01-01

    In evaluating fatty liver with CT, the residual normal liver tissues without fat deposits are occasionally detected on CT as high attenuation regions, especially surrounding the gallbladder. This study examined the incidence of this phenomenon in terms of the diagnostic value of CT in fatty liver. Fifty-seven patients with fatty liver were examined with CT. The incidence of focal sparing area was the highest in the gallbladder bed (42/57, 74%), followed by the interlobar fissure or subcapsular area (13, 23%), quadrate lobe (8, 14%), caudate lobe (2, 4%), and right lobe (one, 1.8%). These CT appearances were of spot, band, ring, and the mixed type. In 38 patients, fatty liver was too moderate to be detected without CT attenuation numbers. Among them, 27 patients (71%) had focal sparing area surrounding the gallbladder. This CT appearance seemed to be of significance in preventing the missing of moderate fatty liver. (Namekawa, K)

  20. Segmented focal plane detector for light and heavy ions

    International Nuclear Information System (INIS)

    Wolfs, F.L.H.; Bryan, D.C.; Kurz, K.L.; Herrick, D.M.; Perera, P.A.A.; White, C.A.

    1992-01-01

    A segmented focal plane detector for an Enge split-pole spectrograph has been developed for the study of breakup reactions at very low relative energies. It consists of a 61 cm long segmented position-sensitive parallel plate avalanche counter backed by a large Bragg curve detector. A segmented plastic scintillator is mounted behind the anode of the Bragg curve detector and is used for particle identification of low-ionizing particles. The dead space between the two sections of the focal plane detector is 2.5 mm. The intrinsic position resolution of the detector is 1 mm. The intrinsic energy resolution depends on the energy of the incident ion and can be as good as 0.55%. The nuclear charge and mass resolutions are 0.3 e and 0.3 u, respectively. (orig.)

  1. Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration.

    Science.gov (United States)

    Wu, Jui-Chung; Chen, Yu-Chen; Kuo, Chih-Ting; Wenshin Yu, Helen; Chen, Yin-Quan; Chiou, Arthur; Kuo, Jean-Cheng

    2015-12-18

    Directed cell migration requires dynamical control of the protein complex within focal adhesions (FAs) and this control is regulated by signaling events involving tyrosine phosphorylation. We screened the SH2 domains present in tyrosine-specific kinases and phosphatases found within FAs, including SRC, SHP1 and SHP2, and examined whether these enzymes transiently target FAs via their SH2 domains. We found that the SRC_SH2 domain and the SHP2_N-SH2 domain are associated with FAs, but only the SRC_SH2 domain is able to be regulated by focal adhesion kinase (FAK). The FAK-dependent association of the SRC_SH2 domain is necessary and sufficient for SRC FA targeting. When the targeting of SRC into FAs is inhibited, there is significant suppression of SRC-mediated phosphorylation of paxillin and FAK; this results in an inhibition of FA formation and maturation and a reduction in cell migration. This study reveals an association between FAs and the SRC_SH2 domain as well as between FAs and the SHP2_N-SH2 domains. This supports the hypothesis that the FAK-regulated SRC_SH2 domain plays an important role in directing SRC into FAs and that this SRC-mediated FA signaling drives cell migration.

  2. A focal plane detector for both light and heavy ions

    International Nuclear Information System (INIS)

    Ophel, T.R.; Johnston, A.

    1978-05-01

    The characteristics of a multi-element, ionization-type focal plane detector with an effective length of 53 cm have been evaluated for various ions ranging between protons and 32 S. The position resolution obtained is typically 1 mm. Excellent energy (0.49% for 16 O) and angular resolution (0.2 degrees with respect to beam direction for 7 Li) have been obtained enabling clean separation of ion species at essentially full angular acceptance of a split-pole spectrograph

  3. Perampanel for focal epilepsy: insights from early clinical experience

    OpenAIRE

    Trinka, E.; Steinhoff, B. J.; Nikanorova, M.; Brodie, M. J.

    2015-01-01

    Perampanel is approved for adjunctive therapy of focal epilepsy with or without secondarily generalized seizures in patients aged >12 years. This narrative review uses real-world and clinical trial data to elucidate perampanel's role in the clinic. Audit data show good tolerability with perampanel and higher freedom-from-seizure rates in elderly vs younger patients. When using perampanel in elderly patients, special attention should be given to comorbidities and co-medication to avoid potenti...

  4. Primary Focal Dystonia: Evidence for Distinct Neuropsychiatric and Personality Profiles

    OpenAIRE

    2009-01-01

    Abstract Background: Primary focal dystonia (PFD) is characterized by motor symptoms. Frequent co-occurrence of abnormal mental conditions has been mentioned for decades but is less well defined. We evaluated prevalence rates of psychiatric disorders, personality disorders and traits in a large cohort of PFD patients. Methods: Prevalence rates of clinical psychiatric diagnoses in 86 PFD patients were compared to a population-based sample (N=3943) using a multiple regress...

  5. The extracellular matrix and altered diffusion in focal cortical dysplasia

    Czech Academy of Sciences Publication Activity Database

    Homola, Aleš; Vargová, Lýdia; Cicanič, Michal; Zámečník, J.; Marusič, P.; Kršek, P.; Syková, Eva

    2011-01-01

    Roč. 59, S1 (2011), S106-S106 ISSN 0894-1491. [European meeting on Glia l Cells in Health and Disease /10./. 13.09.2011-17.09.2011, Prague] R&D Projects: GA MŠk 1M0538; GA ČR GA309/09/1597 Institutional research plan: CEZ:AV0Z50390703 Keywords : focal cortical dysplasia * diffusion * extracellular matrix Subject RIV: FH - Neurology

  6. Atypical Focal Osteomyelitis as Initial Manifestation of AIDS

    OpenAIRE

    A. Akiki; Y. Bilde

    2011-01-01

    Persistent pain development after a skeletal contusion rarely poses the diagnosis of osteomyelitis. We report the case of a fibular head contusion as an initial manifestation of a focal abscess development in a healthy young patient. The traditional treatment of surgical drainage revealed the presence of an atypical Mycobacterium haemophilum isolates in the abscess. This lead to further investigations that concluded and established the diagnosis of AIDS. Conclusion. Isolation of an atypical M...

  7. Explaining focal points: Cognitive hierarchy theory versus team reasoning

    OpenAIRE

    Bardsley, Nicholas; Mehta, Judith; Starmer, Chris; Sugden, Robert

    2008-01-01

    This paper reports experimental tests of two alternative explanations of how players use focal points to select equilibria in one-shot coordination games. Cognitive hierarchy theory explains coordination as the result of common beliefs about players’ pre-reflective inclinations towards the relevant strategies; the theory of team reasoning explains it as the result of the players’ using a non-standard form of reasoning. We report two experiments. One finds strong support for team reasoning; th...

  8. Focal epilepsy with ictal abdominal pain: a case report

    OpenAIRE

    Cerminara, Caterina; El Malhany, Nadia; Roberto, Denis; Curatolo, Paolo

    2013-01-01

    Focal epilepsy with ictal abdominal pain is an unusual partial epilepsy characterized by paroxysmal episodes of abdominal or visceral pain, disturbance of awareness and electroencephalographic abnormalities. We describe a new case of ictal abdominal pain in which gastrointestinal complaints were the only manifestation of seizures and review the previously described pediatric patients. In our patient clinical findings, ictal EEG abnormalities, and a good response to antiepileptic drugs allowed...

  9. Seizure ending signs in patients with dyscognitive focal seizures.

    Science.gov (United States)

    Gavvala, Jay R; Gerard, Elizabeth E; Macken, Mícheál; Schuele, Stephan U

    2015-09-01

    Signs indicating the end of a focal seizure with loss of awareness and/or responsiveness but without progression to focal or generalized motor symptoms are poorly defined and can be difficult to determine. Not recognizing the transition from ictal to postictal behaviour can affect seizure reporting accuracy by family members and may lead to delayed or a lack of examination during EEG monitoring, erroneous seizure localization and inadequate medical intervention for prolonged seizure duration. Our epilepsy monitoring unit database was searched for focal seizures without secondary generalization for the period from 2007 to 2011. The first focal seizure in a patient with loss of awareness and/or responsiveness and/or behavioural arrest, with or without automatisms, was included. Seizures without objective symptoms or inadequate video-EEG quality were excluded. A total of 67 patients were included, with an average age of 41.7 years. Thirty-six of the patients had seizures from the left hemisphere and 29 from the right. All patients showed an abrupt change in motor activity and resumed contact with the environment as a sign of clinical seizure ending. Specific ending signs (nose wiping, coughing, sighing, throat clearing, or laughter) were seen in 23 of 47 of temporal lobe seizures and 7 of 20 extra-temporal seizures. Seizure ending signs are often subtle and the most common finding is a sudden change in motor activity and resumption of contact with the environment. More distinct signs, such as nose wiping, coughing or throat clearing, are not specific to temporal lobe onset. A higher proportion of seizures during sleep went unexamined, compared to those during wakefulness. This demonstrates that seizure semiology can be very subtle and arousals from sleep during monitoring should alert staff. Patient accounts of seizure frequency appear to be unreliable and witness reports need to be taken into account. [Published with video sequences].

  10. Intracoronary infusion of catecholamines causes focal arrhythmias in pigs.

    Science.gov (United States)

    Doppalapudi, Harish; Jin, Qi; Dosdall, Derek J; Qin, Hao; Walcott, Gregory P; Killingsworth, Cheryl R; Smith, William M; Ideker, Raymond E; Huang, Jian

    2008-09-01

    Acute ischemia causes myriad changes including increased catecholamines. We tested the hypothesis that elevated catecholamines alone are arrhythmogenic. A 504 electrode sock was placed over both ventricles in six open-chest pigs. During control infusion of saline through a catheter in the left anterior descending coronary artery (LAD), no sustained arrhythmias occurred, and the refractory period estimated by the activation recovery interval (ARI) was 175 +/- 14 ms in the LAD bed below the catheter. After infusion of isoproterenol at 0.1 microg/kg/min through the catheter, the ARI in this bed was significantly reduced to 109 +/- 10 ms. A sharp gradient of refractoriness of 43 +/- 10 ms was at the border of the perfused bed. Sustained monomorphic ventricular tachycardia occurred after drug infusion in the perfused bed or near its boundary in all animals with a cycle length of 329 +/- 26 ms and a focal origin. The maximum slope of the ARI restitution curve at the focal origins of the tachyarrhythmias was always <1 (0.62 +/- 0.15). Similar results with a focal arrhythmia origin occurred in two additional pigs in which intramural mapping was performed with 36 plunge needle electrodes in the left ventricular perfused bed. Regional elevation of a catecholamine, which is one of the alterations produced by acute ischemia, can by itself cause tachyarrhythmias. These arrhythmias are closely associated with a shortened refractory period and a large gradient of the spatial distribution of refractoriness but not with a steep restitution curve.

  11. [A case of focal epilepsy manifesting multiple psychiatric auras].

    Science.gov (United States)

    Ezura, Michinori; Kakisaka, Yosuke; Jin, Kazutaka; Kato, Kazuhiro; Iwasaki, Masaki; Fujikawa, Mayu; Aoki, Masashi; Nakasato, Nobukazu

    2015-01-01

    We present a case of epilepsy with multiple types of focal seizures that were misdiagnosed as psychiatric disorders. A 20-year-old female patient presented with a variety of episodes, including loss of consciousness, deja vu, fear, delusion of possession, violent movements, and generalized convulsions. Each of these symptoms appeared in a stereotypic manner. She was initially diagnosed with a psychiatric disorder and treated with psychoactive medications, which had no effect. Long-term video electroencephalography revealed that her episodes of violent movement with impaired consciousness and secondarily generalized seizure were epileptic events originating in the right hemisphere. High-field brain magnetic resonance imaging for detecting subtle lesions revealed bilateral lesions from periventricular nodular heterotopia. Her final diagnosis was right hemispheric focal epilepsy. Carbamazepine administration was started, which successfully controlled all seizures. The present case demonstrates the pitfall of diagnosing focal epilepsy when it presents with multiple types of psychiatric aura. Epilepsy should thus be included in differential diagnoses, considering the stereotypic nature of symptoms, to avoid misdiagnosis.

  12. How to diagnose and treat focal therapy failure and recurrence?

    Science.gov (United States)

    Barret, Eric; Harvey-Bryan, Kadi-Ann; Sanchez-Salas, Rafael; Rozet, Francois; Galiano, Marc; Cathelineau, Xavier

    2014-05-01

    Focal therapy presents an alternative option for disease-targeted therapy while preserving erectile and urinary function without compromising oncological outcome. Such treatment, which preserves normal prostate parenchyma, presents a clinical challenge to the urologist, as typical disease surveillance parameters are not as reliable in post-ablation follow-up. We propose an integrated approach to post-ablation surveillance to identify treatment failure as well as recurrence. Post-ablation prostate-specific antigen kinetics, imaging based on multiparametric MRI and control biopsies are the tools currently used to follow patients after focal therapy. Good treatment response is indicated by a negative control biopsy, absence of persistent lesion on post-treatment imaging and a reduction in prostate-specific antigen of at least 50%. When histological evidence of therapeutic failure or recurrence is present, different options of management may be proposed to the patient including active surveillance, focal salvage therapy or radical salvage treatment, depending on the characteristics of the lesion found. A recommended post-ablation surveillance protocol is presented as well as a discussion of management strategies based on the data currently available.

  13. Achromatic Focal Plane Mask for Exoplanet Imaging Coronagraphy

    Science.gov (United States)

    Newman, Kevin Edward; Belikov, Ruslan; Guyon, Olivier; Balasubramanian, Kunjithapatham; Wilson, Dan

    2013-01-01

    Recent advances in coronagraph technologies for exoplanet imaging have achieved contrasts close to 1e10 at 4 lambda/D and 1e-9 at 2 lambda/D in monochromatic light. A remaining technological challenge is to achieve high contrast in broadband light; a challenge that is largely limited by chromaticity of the focal plane mask. The size of a star image scales linearly with wavelength. Focal plane masks are typically the same size at all wavelengths, and must be sized for the longest wavelength in the observational band to avoid starlight leakage. However, this oversized mask blocks useful discovery space from the shorter wavelengths. We present here the design, development, and testing of an achromatic focal plane mask based on the concept of optical filtering by a diffractive optical element (DOE). The mask consists of an array of DOE cells, the combination of which functions as a wavelength filter with any desired amplitude and phase transmission. The effective size of the mask scales nearly linearly with wavelength, and allows significant improvement in the inner working angle of the coronagraph at shorter wavelengths. The design is applicable to almost any coronagraph configuration, and enables operation in a wider band of wavelengths than would otherwise be possible. We include initial results from a laboratory demonstration of the mask with the Phase Induced Amplitude Apodization coronagraph.

  14. Focal lesions in the central nervous system: stereotaxic radioneurosurgery

    International Nuclear Information System (INIS)

    Fabrikant, J.I.; Budinger, T.f.; Hosobuchi, Y.; Born, J.L.; Tobias, C.A.

    1981-01-01

    The application of heavy-ion beams for fundamental and applied brain research has unusual potential. Methods are being developed in our laboratory for producing focal lesions in the central nervous system (e.g., the hypothalamus, thalamus, pituitary gland) to investigate nerve pathways and neuroendocrine responses, and for treating certain pathological disorders of the brain with stereotaxic Bragg peak heavy-ion radiosurgery. Studies in animals are demonstrating the value of this neuroscience tool for investigating mammalian brain response to induction of discrete focal lesions in the hypothalamus or in the cerebral cortex. These studies are also elucidating the neuroendocrinological response follwing ablation of various portions of the midbrain, without requiring complex neurosurgical preparations. Clinical studies are demonstrating the feasibility of stereotaxic neurological radiosurgery for treating certain inoperable vascular disorders of the brain [e.g., arteriovenous malformations (AVM), internal carotid artery-cavernous sinus fistulas and other cerebrovascular disorders] in patients who are already demonstrating progressive neurological deficit. Further applications of focal lesion production with the Bragg ionization peak can be extended to include localized radiation to centers of the brain and spinal cord for treatment of such disorders as Parkinson's disease, pituitary microadenomas, acoustic neuromas, and the control of pain. The eventual application of radioactive beams will provide accurate localization of the stopping points of the beam, thereby making it feasible to stop the beam accurately at a defined depth within the central nervous system

  15. A Micro-Thermal Sensor for Focal Therapy Applications

    Science.gov (United States)

    Natesan, Harishankar; Hodges, Wyatt; Choi, Jeunghwan; Lubner, Sean; Dames, Chris; Bischof, John

    2016-02-01

    There is an urgent need for sensors deployed during focal therapies to inform treatment planning and in vivo monitoring in thin tissues. Specifically, the measurement of thermal properties, cooling surface contact, tissue thickness, blood flow and phase change with mm to sub mm accuracy are needed. As a proof of principle, we demonstrate that a micro-thermal sensor based on the supported “3ω” technique can achieve this in vitro under idealized conditions in 0.5 to 2 mm thick tissues relevant to cryoablation of the pulmonary vein (PV). To begin with “3ω” sensors were microfabricated onto flat glass as an idealization of a focal probe surface. The sensor was then used to make new measurements of ‘k’ (W/m.K) of porcine PV, esophagus, and phrenic nerve, all needed for PV cryoabalation treatment planning. Further, by modifying the sensor use from traditional to dynamic mode new measurements related to tissue vs. fluid (i.e. water) contact, fluid flow conditions, tissue thickness, and phase change were made. In summary, the in vitro idealized system data presented is promising and warrants future work to integrate and test supported “3ω” sensors on in vivo deployed focal therapy probe surfaces (i.e. balloons or catheters).

  16. Strong paleoearthquakes along the Talas-Fergana Fault, Kyrgyzstan

    Directory of Open Access Journals (Sweden)

    A.M. Korzhenkov

    2014-02-01

    Full Text Available The Talas-Fergana Fault, the largest strike-slip structure in Centred. Asia, forms an obliquely oriented boundary between the northeastern and southwestern parts of the Tianshan mountain belt. The fault underwent active right-lateral strike-slip during the Paleozoic, with right-lateral movements being rejuvenated in the Late Cenozoic. Tectonic movements along the intracontinental strike-slip faults contribute to absorb part of the regional crustal shortening linked to the India-Eurasia collision; knowledge of strike-slip motions along the Talas-Fergana Fault are necessary for a complete assessment of the active deformation of the Tianshan orogen. To improve our understanding of the intracontinental deformation of the Tianshan mountain belt and the occurrence of strong earthquakes along the whole length of the Talas-Fergana Fault, we identify features of relief arising during strong paleoearthquakes along the Talas-Fergana Fault, fault segmentation, the length of seismogenic ruptures, and the energy and age of ancient catastrophes. We show that during neotectonic time the fault developed as a dextral strike-slip fault, with possible dextral displacements spreading to secondary fault planes north of the main fault trace. We determine rates of Holocene and Late Pleistocene dextral movements, and our radiocarbon dating indicates tens of strong earthquakes occurring along the fault zone during arid interval of 15800 years. The reoccurrence of strong earthquakes along the Talas-Fergana Fault zone during the second half of the Holocene is about 300 years. The next strong earthquake along the fault will most probably occur along its southeastern chain during the next several decades. Seismotectonic deformation parameters indicate that M > 7 earthquakes with oscillation intensity I > IX have occurred.

  17. Fast multifrequency focal beam analysis for 3D seismic acquisition geometry

    NARCIS (Netherlands)

    Wei, W.; Fu, L.; Blacquiere, G.

    2012-01-01

    A method for the efficient computation of multifrequency focal beams for 3D seismic acquisition geometry analysis has been developed. By computing them for all the frequency components of seismic data, single-frequency focal beams can be extended to multifrequency focal beams. However, this

  18. Geological and Seismological Analysis of the 13 February 2001 Mw 6.6 El Salvador Earthquake: Evidence for Surface Rupture and Implications for Seismic Hazard

    OpenAIRE

    Canora Catalán, Carolina; Martínez Díaz, José J.; Villamor Pérez, María Pilar; Berryman, K.R.; Álvarez Gómez, José Antonio; Pullinger, Carlos; Capote del Villar, Ramón

    2010-01-01

    The El Salvador earthquake of 13 February 2001 (Mw 6.6) caused tectonic rupture on the El Salvador fault zone (ESFZ). Right-lateral strike-slip surface rupture of the east–west trending fault zone had a maximum surface displacement of 0.60 m. No vertical component was observed. The earthquake resulted in widespread landslides in the epicentral area, where bedrock is composed of volcanic sediments, tephra, and weak ignimbrites. In the aftermath of the earthquake, widespread dama...

  19. HIGH PERFORMANCE PIAA CORONAGRAPHY WITH COMPLEX AMPLITUDE FOCAL PLANE MASKS

    International Nuclear Information System (INIS)

    Guyon, Olivier; Martinache, Frantz; Belikov, Ruslan; Soummer, Remi

    2010-01-01

    We describe a coronagraph approach where the performance of a Phase-Induced Amplitude Apodization (PIAA) coronagraph is improved by using a partially transmissive phase-shifting focal plane mask and a Lyot stop. This approach combines the low inner working angle offered by phase mask coronagraphy, the full throughput and uncompromized angular resolution of the PIAA approach, and the design flexibility of Apodized Pupil Lyot Coronagraph. A PIAA complex mask coronagraph (PIAACMC) is fully described by the focal plane mask size, or, equivalently, its complex transmission which ranges from 0 (opaque) to -1 (phase shifting). For all values of the transmission, the PIAACMC theoretically offers full on-axis extinction and 100% throughput at large angular separations. With a pure phase focal plane mask (complex transmission = -1), the PIAACMC offers 50% throughput at 0.64 λ/D while providing total extinction of an on-axis point source. This performance is very close to the 'fundamental performance limit' of coronagraphy derived from first principles. For very high contrast level, imaging performance with PIAACMC is in practice limited by the angular size of the on-axis target (usually a star). We show that this fundamental limitation must be taken into account when choosing the optimal value of the focal plane mask size in the PIAACMC design. We show that the PIAACMC enables visible imaging of Jupiter-like planets at ∼1.2 λ/D from the host star, and can therefore offer almost three times more targets than a PIAA coronagraph optimized for this type of observation. We find that for visible imaging of Earth-like planets, the PIAACMC gain over a PIAA is probably much smaller, as coronagraphic performance is then strongly constrained by stellar angular size. For observations at 'low' contrast (below ∼ 10 8 ), the PIAACMC offers significant performance enhancement over PIAA. This is especially relevant for ground-based high contrast imaging systems in the near-IR, where

  20. Electrophysiological and pathological study of focal cortical dysplasia

    International Nuclear Information System (INIS)

    Hodozuka, Akira; Hashizume, Kiyotaka; Hayashi, Yoshimitsu; Tanaka, Tatsuya

    2008-01-01

    Clinical and experimental studies on focal cortical dysplasia (FCD) were carried out. For the experimental study, an experimental FCD model of rats was developed. Twenty Wistar rats at 0-2 days after birth were used for the study. Kainic acid (KA) solution was injected stereotaxically into medial and lateral sites of the sensori-motor cortex. Bipolar electrodes were inserted. The behavior of the rats and electroencephalography (EEG) were recorded using a digital video-EEG monitoring system. After observation periods of 1, 2 and 6 months, the rats were perfused for pathological study. FCD was observed adjacent to the site of KA injection in all rats more than one month after the injection. EEG recording demonstrated focal spike discharges in and around the site of injection. However, clinical seizure was not observed. Pathological studies showed decrease in gamma aminobutyric acid (GABA)-A receptors and increase in GABA-B receptors not only in the lesion but also in perilesional areas. Fifteen surgical cases of FCD with intractable epilepsy were included in the clinical study. Neuro-imaging studies including high-resolution MRI and single photon emission computed tomography (SPECT) were performed. Conventional EEG studies demonstrated focal EEG abnormalities with epileptic phenomena. At surgery, intraoperative electrocorticography (ECoG) was performed in order to localize epileptic foci under neuroleptanalgesia. Fourteen patients showed epileptiform discharges on preresection ECoG. All foci in non-eloquent areas were resected. Pathological studies including immunohistochemical staining were performed, and characteristics of the FCD in relation to EEG findings were analyzed. Electrophysiological examination revealed epileptogenecity not only in the lesions but also in perilesional areas. In the lesions, immunohistochemical studies showed decrease in GABA-A receptors and increase in GABA-B receptors in both the lesions and perilesional areas, but N

  1. Formation of multiple focal spots using a high NA lens with a complex spiral phase mask

    Science.gov (United States)

    Lalithambigai, K.; Anbarasan, P. M.; Rajesh, K. B.

    2014-07-01

    The formation of a transversally polarized beam by transmitting a tightly focused double-ring-shaped azimuthally polarized beam through a complex spiral phase mask and high numerical aperture lens is presented based on vector diffraction theory. The generation of transversally polarized focal spot segment splitting and multiple focal spots is illustrated numerically. Moreover, we found that a properly designed complex spiral phase mask can move the focal spots along the optical axis in the z direction. Therefore, one can achieve a focal segment of two, three or multiple completely transversely polarized focal spots, which finds applications in optical trapping and in material processing technologies.

  2. 'Focal thyroid inferno' on color Doppler ultrasonography: A specific feature of focal Hashimoto's thyroiditis

    Energy Technology Data Exchange (ETDEWEB)

    Fu, Xianshui, E-mail: fuxs1968@163.com [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Guo, Limei, E-mail: guolimei@bjmu.edu.cn [Department of Pathology, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Zhang, Huabin, E-mail: huabinzhang@bjmu.edu.cn [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Ran, Weiqiang, E-mail: ranwq-sina@vip.sina.com [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Fu, Peng, E-mail: fupeng01@gmail.com [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Li, Zhiqiang, E-mail: lizhq126@126.com [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Chen, Wen, E-mail: wendy7989@sina.com [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Jiang, Ling, E-mail: papayaling@yahoo.com.cn [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Wang, Jinrui, E-mail: jinrui_wang@sina.com [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Jia, Jianwen, E-mail: drjia88@sohu.com [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China)

    2012-11-15

    Purpose: To evaluate color-Doppler features predictive of focal Hashimoto's thyroiditis. Materials and methods: A total of 521 patients with 561 thyroid nodules that underwent surgeries or gun biopsies were included in this study. These nodules were divided into three groups: focal Hashimoto's thyroiditis (104 nodules in 101 patients), benignity other than focal Hashimoto's thyroiditis (73 nodules in 70 patients), and malignancy (358 nodules in 350 patients). On color Doppler sonography, four vascularity types were determined as: hypovascularity, marked internal flow, marked peripheral flow and focal thyroid inferno. The {chi}{sup 2} test was performed to seek the potential vascularity type with the predictive ability of certain thyroid pathology. Furthermore, the gray-scale features of each nodule were also studied. Results: The vascularity type I (hypovascularity) was more often seen in focal Hashimoto's thyroiditis than other benignity and malignancy (46% vs. 20.5% and 19%). While the type II (marked internal flow) showed the opposite tendency (26.9% [focal Hashimoto's thyroiditis] vs. 45.2% [other benignity] and 52.8% [malignancy]). However, type III (marked peripheral flow) was unable to predict any thyroid pathology. Importantly, type IV (focal thyroid inferno) was exclusive to focal Hashimoto's thyroiditis. All 8 type IV nodules appeared to be solid, hypoechoic, and well-defined. Using 'focal thyroid inferno' as an indicator of FHT, the diagnostic sensitivity and specificity were 7.7% and 100% respectively. Conclusions: The vascularity type of 'focal thyroid inferno' is specific for focal Hashimoto thyroiditis. Recognition of this particular feature may avoid unnecessary interventional procedures for some solid hypoechoic thyroid nodules suspicious of malignancy.

  3. FOCAL EPILEPTIC MYOCLONUS IN KOZHEVNIKOV–RASMUSSEN SYNDROME

    Directory of Open Access Journals (Sweden)

    N. E. Kvaskova

    2016-01-01

    Full Text Available The article presents the clinical, electroencephalographic (EEG and neuroimaging features, as well as the results of treatment of patients with focal epileptic myoclonus (FEM with the Kozhevnikov–Rasmussen syndrome (KRS. FEM in KRS-patients was identified in 11 cases, accounting for 0.9 % of all the cases of epilepsy with the onset of seizures up to 18 years (n = 1261. The age at onset of KRS ranged from 3 to 21 years (average – 9.2 ± 5.7 years. In the active period of the disease of all patients in the clinical picture the active FEM appeared and increasing frequency of the secondary generalized seizures (SGS. In addition SGS and FEM, the clinical picture of the disease in most patients (91 % the focal motor (clonic and the somatosensory focal seizures were observed. As the disease progressed, the FEM became more pronounced in frequency and intensity, seized more muscle groups, localizing mainly in the muscles of the trunk and limbs. The typical EEG pattern of FEM patients with KRS was regional epileptiform activity that occurs in the structure of the continued regional slowing localizing maximum of the fronto-central-temporal region. During the magnetic resonance tomography of the brain in dynamics all the patients observed the increase in total cortical hemiatrophy. In all the cases, the appointment of antiepileptic therapy resulted in a slowing of the FEM, however, a complete remission was reached at none of the patients. Two patients were made surgical treatment of epilepsy. In one case remission of epileptic seizures was observed after right-side hemispherotomy. Our study showed that FEM is very resistant type of epileptic seizures. This fact calls for the identification of the FEM at the early stages of the disease with the purpose to improve the prognosis, as well as for an earlier surgical treatment.

  4. Temperament and character properties of primary focal hyperhidrosis patients

    Directory of Open Access Journals (Sweden)

    Ak Mehmet

    2013-01-01

    Full Text Available Abstract Background Primary focal hyperhidrosis is a health problem, which has negative effects on the patient's quality of life and significantly affects the patients’ daily activities, social and business life. The aim of this study is to evaluate temperament and character properties of patients diagnosed with primary focal hyperhidrosis. Methods Fifty-six primary focal hyperhidrosis (22.42 ± 7.80 and 49 control subjects (24.48 ± 5.17 participated in the study. Patients who met the diagnostic criteria for PFH were referred to psychiatry clinic where the subjects were evaluated through Structured Clinical Interview for DSM Disorders-I and Temperament and Character Inventory. Results In order to examine the difference between the PFH and control group in terms of temperament and character properties, one-way Multivariate Analysis of Variance (MANOVA was conducted. In terms of temperament properties, PFH group took significantly higher scores than control group in Fatigability and asthenia dimension. In terms of character properties, PFH group scored significantly lower than control group in Purposefulness , Resourcefulness , Self-Directedness and scored significantly higher than control group in Self-forgetfulness and Self-Transcendence. Conclusion Temperament and character features of PFH patients were different from healthy group and it was considered that these features were affected by many factors including genetic, biological, environmental, socio-cultural elements. During the follow-up of PFH cases, psychiatric evaluation is important and interventions, especially psychotherapeutic interventions can increase the chances of success of the dermatological treatments and can have a positive impact on the quality of life and social cohesion of chronic cases.

  5. Reperfusion promotes mitochondrial dysfunction following focal cerebral ischemia in rats.

    Directory of Open Access Journals (Sweden)

    Jun Li

    Full Text Available BACKGROUND AND PURPOSE: Mitochondrial dysfunction has been implicated in the cell death observed after cerebral ischemia, and several mechanisms for this dysfunction have been proposed. Reperfusion after transient cerebral ischemia may cause continued and even more severe damage to the brain. Many lines of evidence have shown that mitochondria suffer severe damage in response to ischemic injury. The purpose of this study was to observe the features of mitochondrial dysfunction in isolated mitochondria during the reperfusion period following focal cerebral ischemia. METHODS: Male Wistar rats were subjected to focal cerebral ischemia. Mitochondria were isolated using Percoll density gradient centrifugation. The isolated mitochondria were fixed for electron microscopic examination; calcium-induced mitochondrial swelling was quantified using spectrophotometry. Cyclophilin D was detected by Western blotting. Fluorescent probes were used to selectively stain mitochondria to measure their membrane potential and to measure reactive oxidative species production using flow cytometric analysis. RESULTS: Signs of damage were observed in the mitochondrial morphology after exposure to reperfusion. The mitochondrial swelling induced by Ca(2+ increased gradually with the increasing calcium concentration, and this tendency was exacerbated as the reperfusion time was extended. Cyclophilin D protein expression peaked after 24 hours of reperfusion. The mitochondrial membrane potential was decreased significantly during the reperfusion period, with the greatest decrease observed after 24 hours of reperfusion. The surge in mitochondrial reactive oxidative species occurred after 2 hours of reperfusion and was maintained at a high level during the reperfusion period. CONCLUSIONS: Reperfusion following focal cerebral ischemia induced significant mitochondrial morphological damage and Ca(2+-induced mitochondrial swelling. The mechanism of this swelling may be mediated by

  6. Kalman Filter for Calibrating a Telescope Focal Plane

    Science.gov (United States)

    Kang, Bryan; Bayard, David

    2006-01-01

    The instrument-pointing frame (IPF) Kalman filter, and an algorithm that implements this filter, have been devised for calibrating the focal plane of a telescope. As used here, calibration signifies, more specifically, a combination of measurements and calculations directed toward ensuring accuracy in aiming the telescope and determining the locations of objects imaged in various arrays of photodetectors in instruments located on the focal plane. The IPF Kalman filter was originally intended for application to a spaceborne infrared astronomical telescope, but can also be applied to other spaceborne and ground-based telescopes. In the traditional approach to calibration of a telescope, (1) one team of experts concentrates on estimating parameters (e.g., pointing alignments and gyroscope drifts) that are classified as being of primarily an engineering nature, (2) another team of experts concentrates on estimating calibration parameters (e.g., plate scales and optical distortions) that are classified as being primarily of a scientific nature, and (3) the two teams repeatedly exchange data in an iterative process in which each team refines its estimates with the help of the data provided by the other team. This iterative process is inefficient and uneconomical because it is time-consuming and entails the maintenance of two survey teams and the development of computer programs specific to the requirements of each team. Moreover, theoretical analysis reveals that the engineering/ science iterative approach is not optimal in that it does not yield the best estimates of focal-plane parameters and, depending on the application, may not even enable convergence toward a set of estimates.

  7. Brivaracetam: a novel antiepileptic drug for focal-onset seizures.

    Science.gov (United States)

    Stephen, Linda J; Brodie, Martin J

    2018-01-01

    Brivaracetam (BRV), the n -propyl analogue of levetiracetam (LEV), is the latest antiepileptic drug (AED) to be licensed in Europe and the USA for the adjunctive treatment of focal-onset seizures with or without secondary generalization in patients aged 16 years or older. Like LEV, BRV binds to synaptic vesicle protein 2A (SV2A), but BRV has more selective binding and a 15- to 30-fold higher binding affinity than LEV. BRV is more effective than LEV in slowing synaptic vesicle mobilization and the two AEDs may act at different binding sites or interact with different conformational states of the SV2A protein. In animal models, BRV provides protection against focal and secondary generalized seizures and has significant anticonvulsant effects in genetic models of epilepsy. The drug undergoes first-order pharmacokinetics with an elimination half-life of 7-8 h. Although BRV is metabolized extensively, the main circulating compound is unchanged BRV. Around 95% of metabolites undergo renal elimination. No dose reduction is required in renal impairment, but it is recommended that the daily dose is reduced by one-third in hepatic dysfunction that may prolong half-life. BRV has a low potential for drug interactions. The efficacy and tolerability of adjunctive BRV in adults with focal-onset seizures have been explored in six randomized, placebo-controlled studies. These showed significant efficacy outcomes for doses of 50-200 mg/day. The most common adverse events reported were headache, somnolence, dizziness, fatigue and nausea. Patients who develop psychiatric symptoms with LEV appear to be at risk of similar side effects with BRV, although preliminary data suggest that these issues are likely to be less frequent and perhaps less severe. As with all AEDs, a low starting dose and slow titration schedule help to minimize side effects and optimize seizure control and thereby quality of life.

  8. Near infrared focal plane for the ISOCAM camera

    International Nuclear Information System (INIS)

    Epstein, G.; Stefanovitch, D.; Tiphene, D.; Carpentier, Y.; Lorans, D.

    1988-01-01

    ISOCAM is one of the science instruments in the Infrared Space Observatory. It is a 2-channel IR Astronomical Imager intended to observe at very low flux levels, thanks to the use of a liquid helium cooled telescope. This paper describes the Focal Plane Assembly design of the short wavelength channel. The operation of a 32 x 32 InSb CID-SAT array detector has been demonstrated. The problems encountered in the design of the cooled electronics and the component selection process are discussed in the light of specific ISO constraints, such as thermal control and radiation shielding. 6 references

  9. Modeling characterization of the National Ignition Facility focal spot

    International Nuclear Information System (INIS)

    Williams, W.H.

    1998-01-01

    The predicted focal spot size of the National Ignition Facility laser is parameterized against the finish quality of the optics in the system. Results are reported from simulations which include static optics aberrations, as well as pump-induced distortions, beam self-focusing, and the effect of an adaptive optic. The simulations do not include contributions from optics mounting errors, residual thermal noise in laser slabs from previous shots, air turbulence, a kinoform phase plate, or smoothing by spectral dispersion (SSD). Consequently, these results represent ''first shot of the day'', without-SSD, predictions

  10. Difficulties in the interpretation of focal changes on liver scans

    Energy Technology Data Exchange (ETDEWEB)

    Derimanov, S.G. (Oblastnoj Onkologicheskij Dispanser, Veliko-Tyrnovo (Bulgaria))

    1983-01-01

    A series of cases are presented in which erroneous conclusions were arrived at by liver scans. The analysis of these errors has shown that they are determined by the similarity of a scanographic picture of focal changes in various diseases of the liver (cancer, cirrhosis, echinococcus, etc.) and the adjacent organs (bronchogenic cyst, renal tumor, etc.). In this connection all attempts to determine the etiology of a pathological process by liver scans without correlation with the results of multidimensional examination frequently result in errors.

  11. Focal dystonia in musicians: From phenomenology to therapy

    Directory of Open Access Journals (Sweden)

    Hans-Christian Jabusch

    2006-01-01

    Full Text Available Background: Musician's dystonia is a task-specific movement disorder which manifests itself as a loss of voluntary motor control in extensively trained movements. In many cases, the disorder terminates the careers of affected musicians. Approximately 1% of all professional musicians are affected.Etiology and Pathophysiology: The pathophysiology of the disorder is still unclear. Findings include (a reduced inhibition in different levels of the central nervous system, (b maladaptive plasticity, e.g. in the somatosensory cortex and in the basal ganglia, and (c alterations in sensorimotor processing. Epidemiological data demon-strated a higher risk for those musicians who play instruments requiring maximal fine-motorskills. For instruments where workload differs across hands, focal dystonia appears more often in the more intensely used hand. In psychological studies, musicians with dystonia had more perfectionist tendencies than healthy musicians. These findings streng then the assumption that behavioral factors may be involved in the etiology of musician's dystonia. Hereditary factors may play a greater role than previously assumed. Preliminary findings suggest a genetic contributiont o focal task-specific dystonia with phenotypic variations including musician's dystonia.Treatment: Treatment options for musician's dystonia include pharmacological interventions such as administration of Trihexyphenidyl or Botulinum Toxin-A as well as retraining programs and ergonomic changes in the instrument. A long-term follow-up study was performed in 144 patients with musician's dystonia. The outcome was revealed on average 8.4 years after onset of symptoms. Outcome was assessed by patients' subjective rating of cumulative treatmentresponse and response to individual therapies. Seventy-seven patients (54% reported an alleviation of symptoms: 33% of the patients with Trihexyphenidyl, 49% with Botulinum Toxin, 50% with pedagogical retraining, 56% with unmonitored

  12. Immunogenic hyperthyroidism following radioiodine ablation of focal autonomy

    International Nuclear Information System (INIS)

    Boddenberg, B.; Voth, E.; Schicha, H.

    1993-01-01

    Immunogenic hyperthyroidism rarely develops after radioiodine elimination of focal autonomous thyroid tissue. We observed this phenomenon in 8 patients between 1989 and 1992. The occurrence of immunogenic hyperthyroidism shortly after elimination of autonomous nodules has not been studied nor is it properly understood. Most studies known today describe the development of autonomous nodules in the course of immunogenic hyperthyroidism or ignore the chronologic order of occurrence. The possibility that immunogenic hyperthyroidism may occur after radioiodine therapy of autonomous nodules, makes a consequent follow-up within the first year following radioiodine therapy mandatory. (orig.) [de

  13. New focal plane detector system for the broad range spectrometer

    International Nuclear Information System (INIS)

    Sjoreen, T.P.

    1984-01-01

    A focal plane detector system consisting of a vertical drift chamber, parallel plate avalanche counters, and an ionization chamber with segmented anodes has been installed in the Broad Range Spectrometer at the Holifield Facility at Oak Ridge. The system, which has been designed for use with light-heavy ions with energies ranging from 10 to 25 MeV/amu, has a position resolution of approx. 0.1 mm, a scattering angle resolution of approx. 3 mrad, and a mass resolution of approx. 1/60

  14. Focal cemento-osseous dysplasia masquerading as a residual cyst.

    Science.gov (United States)

    Bhandari, Rajat; Sandhu, Simarpreet V; Bansal, Himanta; Behl, Rashi; Bhullar, Ramanpreet Kaur

    2012-04-01

    Focal cemento-osseous dysplasia (FCOD) is a benign fibroosseous condition that can be seen in dentulous and edentulous patients. It is an asymptomatic lesion and needs no treatment; however, follow-up is essential due to the possibility that it can progress to a condition called florid cemento-osseous dysplasia. We report a case of FCOD of mandible in a 25-year-old female. Clinically, the lesion resembled periapical pathosis of odontogenic origin. An attempt has been made to discuss the clinical and histopathologic features along with differential diagnosis of cemento-osseous dysplasia.

  15. Focal cemento-osseous dysplasia masquerading as a residual cyst

    Directory of Open Access Journals (Sweden)

    Rajat Bhandari

    2012-01-01

    Full Text Available Focal cemento-osseous dysplasia (FCOD is a benign fibroosseous condition that can be seen in dentulous and edentulous patients. It is an asymptomatic lesion and needs no treatment; however, follow-up is essential due to the possibility that it can progress to a condition called florid cemento-osseous dysplasia. We report a case of FCOD of mandible in a 25-year-old female. Clinically, the lesion resembled periapical pathosis of odontogenic origin. An attempt has been made to discuss the clinical and histopathologic features along with differential diagnosis of cemento-osseous dysplasia.

  16. Slow Activity in Focal Epilepsy During Sleep and Wakefulness

    DEFF Research Database (Denmark)

    Pellegrino, Giovanni; Tombini, Mario; Curcio, Giuseppe

    2017-01-01

    Introduction We aimed to test differences between healthy subjects and patients with respect to slow wave activity during wakefulness and sleep. Methods Fifteen patients affected by nonlesional focal epilepsy originating within temporal areas and fourteen matched controls underwent a 24-hour EEG....... The effect was widespread for alpha band and above, while localized over the affected hemisphere for delta (sleep cycle 1, P = .006; sleep cycle 2, P = .008; sleep cycle 3, P = .017). The analysis of interhemispheric differences showed that the only frequency band stronger over the affected regions...

  17. Caso severo de manifestaciones bucales de la hiperplasia epitelial focal

    OpenAIRE

    Jonathan Harris Ricardo; Natalia Fortich Mesa

    2012-01-01

    La hiperplasia epitelial focal, conocida también como enfermedad de Heck, es una patología benigna que se caracteriza por la presencia de múltiples pápulas en la mucosa de la cavidad bucal; es producida por los subtipos 13 y 32 del virus del papiloma humano, aunque también se le relaciona con factores genéticos, inmunosupresión e higiene bucal deficiente pero con poco sustento científico; afecta principalmente a niños y adolescentes. Se reporta caso clínico de paciente femenina de 7 años de e...

  18. Focal plane array with modular pixel array components for scalability

    Science.gov (United States)

    Kay, Randolph R; Campbell, David V; Shinde, Subhash L; Rienstra, Jeffrey L; Serkland, Darwin K; Holmes, Michael L

    2014-12-09

    A modular, scalable focal plane array is provided as an array of integrated circuit dice, wherein each die includes a given amount of modular pixel array circuitry. The array of dice effectively multiplies the amount of modular pixel array circuitry to produce a larger pixel array without increasing die size. Desired pixel pitch across the enlarged pixel array is preserved by forming die stacks with each pixel array circuitry die stacked on a separate die that contains the corresponding signal processing circuitry. Techniques for die stack interconnections and die stack placement are implemented to ensure that the desired pixel pitch is preserved across the enlarged pixel array.

  19. Subdural Empyema Presenting with Seizure, Confusion, and Focal Weakness

    Directory of Open Access Journals (Sweden)

    David I Bruner

    2012-12-01

    Full Text Available While sinusitis is a common ailment, intracranial suppurative complications of sinusitis are rare and difficult to diagnose and treat. The morbidity and mortality of intracranial complications of sinusitis have decreased significantly since the advent of antibiotics, but diseases such as subdural empyemas and intracranial abscesses still occur, and they require prompt diagnosis, treatment, and often surgical drainage to prevent death or long-term neurologic sequelae. We present a case of an immunocompetent adolescent male with a subdural empyema who presented with seizures,confusion, and focal arm weakness after a bout of sinusitis.

  20. Subdural Empyema Presenting with Seizure, Confusion, and Focal Weakness

    Science.gov (United States)

    Bruner, David I.; Littlejohn, Lanny; Pritchard, Amy

    2012-01-01

    While sinusitis is a common ailment, intracranial suppurative complications of sinusitis are rare and difficult to diagnose and treat. The morbidity and mortality of intracranial complications of sinusitis have decreased significantly since the advent of antibiotics, but diseases such as subdural empyemas and intracranial abscesses still occur, and they require prompt diagnosis, treatment, and often surgical drainage to prevent death or long-term neurologic sequelae. We present a case of an immunocompetent adolescent male with a subdural empyema who presented with seizures, confusion, and focal arm weakness after a bout of sinusitis. PMID:23358438

  1. Electrodiagnosis in the management of focal neuropathies: the "WOG" syndrome.

    Science.gov (United States)

    Brown, W F; Dellon, A L; Campbell, W W

    1994-11-01

    The role of electrodiagnosis in managing patients with focal neuropathies is discussed from the differing perspectives of a peripheral nerve surgeon and a practitioner of electrodiagnostic medicine. Both clinical evaluation and electrodiagnosis are useful methodologies, each having limitations. Dr. Dellon labels the overreliance on electrodiagnosis and the "WOG" (Word of God) syndrome, and describes its signs, symptoms, and treatment. Dr. Brown contends Dr. Dellon's crusade is misdirected. The exchange is an eloquent polemic on the virtues and foibles of these different approaches to evaluating peripheral nerve function and the imperative to practice them in a complementary rather than a contentious manner.

  2. Past Tense in Children with Focal Brain Lesions

    OpenAIRE

    Konstantinopoulou, P.; Stavrakaki, S.; Manouilidou, C.; Zafeiriou, D.

    2013-01-01

    In this study, 22 children with early left hemisphere (LHD) or right hemisphere (RHD) focal brain lesions (FL, n ¼ 14 LHD,\\ud n ¼ 8 RHD) were administered an English past tense elicitation test (M ¼ 6:5 years). Proportion correct and frequency of overregularization\\ud and zero-marking errors were compared to age-matched samples of children with specific language impairment (SLI,\\ud n ¼ 27) and with typical language development (TD, n ¼ 27). Similar rates of correct production and error patter...

  3. The immunological synapse: a focal point for endocytosis and exocytosis.

    Science.gov (United States)

    Griffiths, Gillian M; Tsun, Andy; Stinchcombe, Jane C

    2010-05-03

    There are many different cells in the immune system. To mount an effective immune response, they need to communicate with each other. One way in which this is done is by the formation of immunological synapses between cells. Recent developments show that the immune synapse serves as a focal point for exocytosis and endocytosis, directed by centrosomal docking at the plasma membrane. In this respect, formation of the immunological synapse bears striking similarities to cilia formation and cytokinesis. These intriguing observations suggest that the centrosome may play a conserved role in designating a specialized area of membrane for localized endocytosis and exocytosis.

  4. Cosmetic Effect of Botulinum Toxin In Focal Hyperhydrosis

    Directory of Open Access Journals (Sweden)

    Jain S

    2005-01-01

    Full Text Available Hyperhydrosis of axillae, palm and sole is not a very uncommon problem. It leads to great embarrassment and considerable emotional stress to the individuals. Botulinum toxins prevent the release of acetylcholine at nerve terminals, therefore, reduces sweat secretion. Six patients of axillary and 4 patients of palmer and planter hyperhydrosis were treated with botulinum toxin. All patients experienced relatively satisfactory reduction of hyperhydrosis for period ranging between 4-7 months. No adverse effects were observed. Botulinum toxin therefore can be considered as an effective treatment in focal hyperhydrosis.

  5. Radiofrequency Ablation Effectively Treated Focal Recurrence of Mesothelioma.

    Science.gov (United States)

    Nakamura, Akifumi; Takuwa, Teruhisa; Hashimoto, Masaki; Kondo, Nobuyuki; Takaki, Haruyuki; Fujiwara, Masayuki; Yamakado, Koichiro; Hasegawa, Seiki

    2018-02-01

    A 55-year-old man with malignant pleural mesothelioma underwent multimodality treatment comprising induction chemotherapy followed by extrapleural pneumonectomy and radiation therapy. After 2.5 years, focal recurrence occurred, with computed tomography revealing a tumor in the left cardiophrenic angle. Surgery was considered a problem for the patient because of the previous extrapleural pneumonectomy and difficult tumor location. Radiofrequency ablation was thus performed; the course was uneventful, and there was no recurrence. Radiofrequency ablation should be considered an option to treat recurrence of malignant pleural mesothelioma. Copyright © 2018 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  6. RMT focal plane sensitivity to seismic network geometry and faulting style

    Science.gov (United States)

    Johnson, Kendra L.; Hayes, Gavin; Herrmann, Robert B.; Benz, Harley M.; McNamara, Daniel E.; Bergman, Eric A.

    2016-01-01

    by Scenario 1, with a range of 26°. We draw two main conclusions from this study. (1) Station distribution impacts our ability to constrain RMTs using waveform time-series; however, in some tectonic settings, faulting style also plays a significant role and (2) increasing station density and data quantity (both the number of stations and the number of individual channels) does not necessarily improve RMT constraint. These results may be useful when organizing future seismic deployments (e.g. by concentrating stations in alignment with anticipated nodal planes), and in computing RMTs, either by guiding a more rigorous data selection process for input data or informing variable weighting among the selected data (e.g. by eliminating the transverse component when strike-slip mechanisms are expected).

  7. Focal colors across languages are representative members of color categories.

    Science.gov (United States)

    Abbott, Joshua T; Griffiths, Thomas L; Regier, Terry

    2016-10-04

    Focal colors, or best examples of color terms, have traditionally been viewed as either the underlying source of cross-language color-naming universals or derived from category boundaries that vary widely across languages. Existing data partially support and partially challenge each of these views. Here, we advance a position that synthesizes aspects of these two traditionally opposed positions and accounts for existing data. We do so by linking this debate to more general principles. We show that best examples of named color categories across 112 languages are well-predicted from category extensions by a statistical model of how representative a sample is of a distribution, independently shown to account for patterns of human inference. This model accounts for both universal tendencies and variation in focal colors across languages. We conclude that categorization in the contested semantic domain of color may be governed by principles that apply more broadly in cognition and that these principles clarify the interplay of universal and language-specific forces in color naming.

  8. VERIFICATION OF THE SENTINEL-4 FOCAL PLANE SUBSYSTEM

    Directory of Open Access Journals (Sweden)

    C. Williges

    2017-05-01

    Full Text Available The Sentinel-4 payload is a multi-spectral camera system which is designed to monitor atmospheric conditions over Europe. The German Aerospace Center (DLR in Berlin, Germany conducted the verification campaign of the Focal Plane Subsystem (FPS on behalf of Airbus Defense and Space GmbH, Ottobrunn, Germany. The FPS consists, inter alia, of two Focal Plane Assemblies (FPAs, one for the UV-VIS spectral range (305 nm … 500 nm, the second for NIR (750 nm … 775 nm. In this publication, we will present in detail the opto-mechanical laboratory set-up of the verification campaign of the Sentinel-4 Qualification Model (QM which will also be used for the upcoming Flight Model (FM verification. The test campaign consists mainly of radiometric tests performed with an integrating sphere as homogenous light source. The FPAs have mainly to be operated at 215 K ± 5 K, making it necessary to exploit a thermal vacuum chamber (TVC for the test accomplishment. This publication focuses on the challenge to remotely illuminate both Sentinel-4 detectors as well as a reference detector homogeneously over a distance of approximately 1 m from outside the TVC. Furthermore selected test analyses and results will be presented, showing that the Sentinel-4 FPS meets specifications.

  9. Encephalitozoon cuniculi causes focal anterior cataract and uveitis in dogs.

    Science.gov (United States)

    Nell, B; Csokai, J; Fuchs-Baumgartinger, A; Maaß, G

    2015-01-01

    Three mongrel dogs, aged 10 months (case 1), 14 months (case 2) and 7.5 years (case 3), were presented because of ophthalmologic disorders of 4 months, 6 months and 7 years duration, respectively. All three dogs were offspring of stray dogs from Hungary and Serbia and had positive serum antibody titres against Encephalitozoon (E.) cuniculi. The two young dogs showed unilateral, the older dog bilateral chronic anterior uveitis with posterior synechia and focal anterior cortical cataract. The fundi that could be evaluated developed focal tapetal hyporeflective lesions in the course of the disease. Dogs 1 and 2 underwent removal of the lens via phacoemulsification. PCR of the lens material was positive for E. cuniculi strains IV and II, respectively. In dog 2 findings suggestive of microsporidia were detected underneath the anterior lens capsule by immunohistochemical staining. In all cases medical treatment consisted of systemic fenbendazole, prednisolone, and topical anti-inflammatory drugs, and additional brinzolamid/timolol for dog 3. For the time being all cases (follow up 23 months, 6 months and 3 months, respectively) are still on topical anti-inflammatory therapy. It is concluded that E. cuniculi infections can cause cataract and chorioretinal lesions in dogs.

  10. Transcranial Magnetic Stimulation-coil design with improved focality

    Science.gov (United States)

    Rastogi, P.; Lee, E. G.; Hadimani, R. L.; Jiles, D. C.

    2017-05-01

    Transcranial Magnetic Stimulation (TMS) is a technique for neuromodulation that can be used as a non-invasive therapy for various neurological disorders. In TMS, a time varying magnetic field generated from an electromagnetic coil placed on the scalp is used to induce an electric field inside the brain. TMS coil geometry plays an important role in determining the focality and depth of penetration of the induced electric field responsible for stimulation. Clinicians and basic scientists are interested in stimulating a localized area of the brain, while minimizing the stimulation of surrounding neural networks. In this paper, a novel coil has been proposed, namely Quadruple Butterfly Coil (QBC) with an improved focality over the commercial Figure-8 coil. Finite element simulations were conducted with both the QBC and the conventional Figure-8 coil. The two coil's stimulation profiles were assessed with 50 anatomically realistic MRI derived head models. The coils were positioned on the vertex and the scalp over the dorsolateral prefrontal cortex to stimulate the brain. Computer modeling of the coils has been done to determine the parameters of interest-volume of stimulation, maximum electric field, location of maximum electric field and area of stimulation across all 50 head models for both coils.

  11. Caso severo de manifestaciones bucales de la hiperplasia epitelial focal

    Directory of Open Access Journals (Sweden)

    Jonathan Harris Ricardo

    2012-01-01

    Full Text Available La hiperplasia epitelial focal, conocida también como enfermedad de Heck, es una patología benigna que se caracteriza por la presencia de múltiples pápulas en la mucosa de la cavidad bucal; es producida por los subtipos 13 y 32 del virus del papiloma humano, aunque también se le relaciona con factores genéticos, inmunosupresión e higiene bucal deficiente pero con poco sustento científico; afecta principalmente a niños y adolescentes. Se reporta caso clínico de paciente femenina de 7 años de edad, remitida al servicio de Estomatología y Cirugía Oral de la Corporación Universitaria Rafael Núñez por presentar múltiples pápulas en mucosa bucal, de tamaño variable, asintomáticas, 8 meses de evolución, relacionadas clínicas e histológicamente con hiperplasia epitelial focal.

  12. High operating temperature interband cascade focal plane arrays

    Energy Technology Data Exchange (ETDEWEB)

    Tian, Z.-B.; Godoy, S. E.; Kim, H. S.; Schuler-Sandy, T.; Montoya, J. A.; Krishna, S. [Center for High Technology Materials, Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque, New Mexico 87106 (United States)

    2014-08-04

    In this paper, we report the initial demonstration of mid-infrared interband cascade (IC) photodetector focal plane arrays with multiple-stage/junction design. The merits of IC photodetectors include low noise and efficient photocarrier extraction, even for zero-bias operation. By adopting enhanced electron barrier design and a total absorber thickness of 0.7 μm, the 5-stage IC detectors show very low dark current (1.10 × 10{sup −7} A/cm{sup 2} at −5 mV and 150 K). Even with un-optimized fabrication and standard commercial (mis-matched) read-out circuit technology, infrared images are obtained by the 320 × 256 IC focal plane array up to 180 K with f/2.3 optics. The minimum noise equivalent temperature difference of 28 mK is obtained at 120 K. These initial results indicate great potential of IC photodetectors, particularly for high operating temperature applications.

  13. High operating temperature interband cascade focal plane arrays

    International Nuclear Information System (INIS)

    Tian, Z.-B.; Godoy, S. E.; Kim, H. S.; Schuler-Sandy, T.; Montoya, J. A.; Krishna, S.

    2014-01-01

    In this paper, we report the initial demonstration of mid-infrared interband cascade (IC) photodetector focal plane arrays with multiple-stage/junction design. The merits of IC photodetectors include low noise and efficient photocarrier extraction, even for zero-bias operation. By adopting enhanced electron barrier design and a total absorber thickness of 0.7 μm, the 5-stage IC detectors show very low dark current (1.10 × 10 −7 A/cm 2 at −5 mV and 150 K). Even with un-optimized fabrication and standard commercial (mis-matched) read-out circuit technology, infrared images are obtained by the 320 × 256 IC focal plane array up to 180 K with f/2.3 optics. The minimum noise equivalent temperature difference of 28 mK is obtained at 120 K. These initial results indicate great potential of IC photodetectors, particularly for high operating temperature applications

  14. Multivariate analysis of magnetic resonance imaging of focal hepatic lesions

    International Nuclear Information System (INIS)

    Fujishima, Mamoru; Suemitsu, Ichizou; Sei, Tetsurou; Takeda, Yoshihiro; Hiraki, Yoshio

    1993-01-01

    A total of 124 lesions from 1 to 6 cm in diameter, including 31 cavernous hemangiomas, 32 metastases and 61 hepatocellular carcinomas (HCC) were analyzed to study the usefulness of magnetic resonance imaging (MRI) at 0.5 Tesla to differentiate focal hepatic lesions on the basis of qualitative criteria. Each focal hepatic lesion was assessed for shape, internal architecture and signal intensity relative to normal liver parenchyma. While all cavernous hemangiomas and metastases except one lesion could be detected, detection rate of HCC was significantly inferior to that of the other two diseases. A tumor capsule and a hyperintense focus on T 1 -weighted images were demonstrated in only HCC lesions in strong contrast with the other two diseases; however, metastases with slow-growing characteristics or subacute hematoma may appear as similar images. Cavernous hemangiomas appeared markedly hyperintense on T 2 -weighted images in 23 of 31 lesions, but one metastasis and one HCC had similar images. A multivariate analysis of several MRI resulted in the following mean discriminant scores: cavernous hemangioma, -1.2652; metastasis, 0.1830; and HCC, 0.7138. It appeared to be possible to differentiate the three diseases with 84.4 percent accuracy. (author)

  15. Verification of the Sentinel-4 focal plane subsystem

    Science.gov (United States)

    Williges, Christian; Uhlig, Mathias; Hilbert, Stefan; Rossmann, Hannes; Buchwinkler, Kevin; Babben, Steffen; Sebastian, Ilse; Hohn, Rüdiger; Reulke, Ralf

    2017-09-01

    The Sentinel-4 payload is a multi-spectral camera system, designed to monitor atmospheric conditions over Europe from a geostationary orbit. The German Aerospace Center, DLR Berlin, conducted the verification campaign of the Focal Plane Subsystem (FPS) during the second half of 2016. The FPS consists, of two Focal Plane Assemblies (FPAs), two Front End Electronics (FEEs), one Front End Support Electronic (FSE) and one Instrument Control Unit (ICU). The FPAs are designed for two spectral ranges: UV-VIS (305 nm - 500 nm) and NIR (750 nm - 775 nm). In this publication, we will present in detail the set-up of the verification campaign of the Sentinel-4 Qualification Model (QM). This set up will also be used for the upcoming Flight Model (FM) verification, planned for early 2018. The FPAs have to be operated at 215 K +/- 5 K, making it necessary to exploit a thermal vacuum chamber (TVC) for the test accomplishment. The test campaign consists mainly of radiometric tests. This publication focuses on the challenge to remotely illuminate both Sentinel-4 detectors as well as a reference detector homogeneously over a distance of approximately 1 m from outside the TVC. Selected test analyses and results will be presented.

  16. O uso do grupo focal em pesquisa qualitativa

    Directory of Open Access Journals (Sweden)

    Lúcia Beatriz Ressel

    2008-01-01

    Full Text Available Este estudio tuvo como objetivo presentar el uso del grupo focal como técnica de recolección de datos en una tesis de doctorado, resultado de una investigación cualitativa. El grupo focal utiliza sesiones grupales de discusión, teniendo como foco central un tópico específico a ser debatido por los participantes. La investigación focalizó la temática de la sexualidad en la asistencia de enfermería, bajo una perspectiva cultural, siendo desarrollada con dos grupos de enfermeras: docentes y asistenciales. Comprendió ocho encuentros, y cada uno fue planeado por separado. La evaluación del proceso se realizó por medio de entrevistas con las enfermeras, destacando como puntos positivos la conducción hacia el pensamiento crítico y al proceso de desalineación; y la posibilidad de que esta técnica revele significados singulares y a que ellos se relacionen desde el punto de vista de los sujetos investigados. Esa técnica facilitó el abordaje de la sexualidad, desconstruyendo y reconstruyendo conceptos y buscando respuestas para las inquietudes del tema.

  17. Differentiation of focal liver lesions by contrast-enhanced MRI

    International Nuclear Information System (INIS)

    Heintz, P.; Ehrenheim, C.

    1989-01-01

    47 patients with liver tumours (haemangioma, focal nodular hyperplasia, hepatocellular carcinoma) underwent MRI of the liver before and after i.v. injection of 0.2 ml./kg. gadolinium-DTPA in addition to other imaging methods. The demarcation of focal nodular hyperplasia is not influenced by use of the contrast agent as it almost behaves like surrounding normal liver tissue, thus only indirectly facilitating its identification. With regard to liver haemangiomas that show the most intensive uptake of gadolinium-DTPA, the contrast enhanced image does not reach to contrast and sensitivity of a native T 2 -weighted SE image, especially in cases of small haemangiomas. The contrast agent is helpful, however, in the recognition of large cavernous haemangiomas that are partially fibrotic or thrombotic. Emphasis is given to the contrast agent in hepatomas: gadolinium-DTPA presents a pattern of uptake and distribution frequently found in hepatocellular carcinoma providing additional information on the delineation of internal tumour details. (orig.) [de

  18. Zinc translocation accelerates infarction after mild transient focal ischemia.

    Science.gov (United States)

    Lee, J-M; Zipfel, G J; Park, K H; He, Y Y; Hsu, C Y; Choi, D W

    2002-01-01

    Excess release of chelatable zinc (Zn(2+)) from central synaptic vesicles may contribute to the pathogenesis of selective neuronal cell death following transient forebrain ischemia, but a role in neurodegeneration after focal ischemia has not been defined. Adult male Long-Evans rats subjected to middle cerebral artery occlusion (MCAO) for 30 min followed by reperfusion developed delayed cerebral infarction reaching completion 3 days after the insult. One day after the insult, many degenerating cerebral neurons exhibited increased intracellular Zn(2+), and some labeled with the antibody against activated caspase-3. I.c.v. administration of the Zn(2+) chelator, EDTA saturated with equimolar Ca(2+) (CaEDTA), 15 min prior to ischemia attenuated subsequent Zn(2+) translocation into cortical neurons, and reduced infarct volume measured 3 days after ischemia. Although the protective effect of CaEDTA at this endpoint was substantial (about 70% infarct reduction), it was lost when insult severity was increased (from 30 to 60 min MCAO), or when infarct volume was measured at a much later time point (14 days instead of 3 days after ischemia). These data suggest that toxic Zn(2+) translocation, from presynaptic terminals to post-synaptic cell bodies, may accelerate the development of cerebral infarction following mild transient focal ischemia.

  19. Focal neuronal loss, reversible subcortical focal T2 hypointensity in seizures with a nonketotic hyperglycemic hyperosmolar state

    International Nuclear Information System (INIS)

    Raghavendra, S.; Ashalatha, R.; Thomas, Sanjeev V.; Kesavadas, C.

    2007-01-01

    Neuroimaging in seizures associated with nonketotic hyperglycemia (NKH) is considered normal. We report magnetic resonance imaging (MRI) abnormalities in four patients with NKH and seizures. We prospectively evaluated clinical and radiological abnormalities in four patients with NKH during the period March 2004 to December 2005. All patients presented with seizures, either simple or complex partial seizures or epilepsia partialis continua. Two of them had transient hemianopia. MRI showed subcortical T2 hypointensity in the occipital white matter and in or around the central sulcus (two patients each), T2 hyperintensity of the overlying cortex (two patients), focal overlying cortical enhancement (three patients) and bilateral striatal hyperintensity (one patient). Diffusion-weighted imaging (DWI) performed in three patients showed restricted diffusion. The ictal semiology and electroencephalographic (EEG) findings correlated with the MRI abnormalities. On clinical recovery, the subcortical T2 hypointensity and striatal hyperintensity reversed in all patients. The initial cortical change evolved to FLAIR hyperintensity suggestive of focal cortical gliosis. The radiological differential diagnosis considered initially included encephalitis, malignancy and hemorrhagic infarct rendering a diagnostic dilemma. We identified subcortical T2 hypointensity rather than hyperintensity as a characteristic feature of seizures associated with NKH. Only very few similar reports exist in literature. Reversible bilateral striatal T2 hyperintensity in NKH has not been reported to the best of our knowledge. (orig.)

  20. Focal neuronal loss, reversible subcortical focal T2 hypointensity in seizures with a nonketotic hyperglycemic hyperosmolar state

    Energy Technology Data Exchange (ETDEWEB)

    Raghavendra, S.; Ashalatha, R.; Thomas, Sanjeev V. [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Neurology, Trivandrum, Kerala (India); Kesavadas, C. [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Imaging Sciences and Interventional Radiology, Trivandrum (India)

    2007-04-15

    Neuroimaging in seizures associated with nonketotic hyperglycemia (NKH) is considered normal. We report magnetic resonance imaging (MRI) abnormalities in four patients with NKH and seizures. We prospectively evaluated clinical and radiological abnormalities in four patients with NKH during the period March 2004 to December 2005. All patients presented with seizures, either simple or complex partial seizures or epilepsia partialis continua. Two of them had transient hemianopia. MRI showed subcortical T2 hypointensity in the occipital white matter and in or around the central sulcus (two patients each), T2 hyperintensity of the overlying cortex (two patients), focal overlying cortical enhancement (three patients) and bilateral striatal hyperintensity (one patient). Diffusion-weighted imaging (DWI) performed in three patients showed restricted diffusion. The ictal semiology and electroencephalographic (EEG) findings correlated with the MRI abnormalities. On clinical recovery, the subcortical T2 hypointensity and striatal hyperintensity reversed in all patients. The initial cortical change evolved to FLAIR hyperintensity suggestive of focal cortical gliosis. The radiological differential diagnosis considered initially included encephalitis, malignancy and hemorrhagic infarct rendering a diagnostic dilemma. We identified subcortical T2 hypointensity rather than hyperintensity as a characteristic feature of seizures associated with NKH. Only very few similar reports exist in literature. Reversible bilateral striatal T2 hyperintensity in NKH has not been reported to the best of our knowledge. (orig.)

  1. Hiperceratose focal acral associada à hipocromia de dermatóglifos Focal acral hyperkeratosis with hypochromic dermatoglyphics

    Directory of Open Access Journals (Sweden)

    Roberto Rheingantz da Cunha Filho

    2008-10-01

    Full Text Available Hiperceratose focal acral é dermatose rara caracterizada por pápulas ceratóticas acrais que afetam preferencialmente as superfícies marginais das mãos e dos pés, pertencendo ao grupo das hiperceratoses marginais. Apresentamos variante inédita de mulher de 45 anos de idade, branca, dona-de-casa, sem história familiar, com lesões ceratóticas papulosas localizadas nos pés e hipocromia de dermatóglifos na região afetada. Histologicamente apresentou hiperortoceratose, desnível da epiderme (degrau, acantose e hipergranulose. Os tratamentos com ceratolíticos tópicos foram ineficientes, de forma semelhante aos casos descritos na literatura atual.Focal acral hyperkeratosis is a rare condition, characterized by acral keratotic papules that preferably affect hand and foot surfaces, and are included in the spectrum of marginal papular keratodermas. We report an unpublished variant of this condition, the case of a 45-year-old Caucasian woman with acral keratotic papular lesions and hypochromic dermatoglyphics in the feet. Histological examination revealed orthohyperkeratosis, depression of the epidermis, acanthosis and hypergranulosis. Topical treatments with keratolytics were ineffective, similarly to previously described cases.

  2. 99mTc-HM-PAO SPECT of epileptic patients showing focal paroxysm on electroencephalography

    International Nuclear Information System (INIS)

    Takaishi, Yasuko; Hashimoto, Kiyoshi; Fujino, Osamu; Kamayachi, Satoshi; Fujita, Takehisa; Enokido, Hisashi; Komatsuzaki, Hideki; Kawakami, Yasuhiko; Hirayama, Tsunenori

    1995-01-01

    The usefulness of 99m Tc-HM-PAO SPECT in diagnosing epilepsy was studied. The subjects were 33 epileptic patients, ranging in age from 5 years and 5 months to 28 years and 3 months, who showed focal paroxysm on electroencephalograms. Lowered accumulation site was found on SPECT in 19 patients. Four patients with abnormal findings on X-ray CT or MRI showed lowered accumulation and focal paroxysm at the same site. Of 29 patients with normal X-ray CT or MRI findings, 15 (52%) showed lowered accumulation. Five patients showed a focal paroxysm at the site of lowered accumulation. In 8 patients the focal paroxysm site was partly coincided with the accumulation site. In some patients the focal site predicted by the findings of clinical symptoms and the lowered accumulation site coincided. SPECT is therefore a useful method in diagnosing a focal site in epilepsy and considered to reflect the severity of disease. (Y.S.)

  3. The 1911 M ~6.6 Calaveras earthquake: Source parameters and the role of static, viscoelastic, and dynamic coulomb stress changes imparted by the 1906 San Francisco earthquake

    Science.gov (United States)

    Doser, D.I.; Olsen, K.B.; Pollitz, F.F.; Stein, R.S.; Toda, S.

    2009-01-01

    The occurrence of a right-lateral strike-slip earthquake in 1911 is inconsistent with the calculated 0.2-2.5 bar static stress decrease imparted by the 1906 rupture at that location on the Calaveras fault, and 5 yr of calculated post-1906 viscoelastic rebound does little to reload the fault. We have used all available first-motion, body-wave, and surface-wave data to explore possible focal mechanisms for the 1911 earthquake. We find that the event was most likely a right-lateral strikeslip event on the Calaveras fault, larger than, but otherwise resembling, the 1984 Mw 6.1 Morgan Hill earthquake in roughly the same location. Unfortunately, we could recover no unambiguous surface fault offset or geodetic strain data to corroborate the seismic analysis despite an exhaustive archival search. We calculated the static and dynamic Coulomb stress changes for three 1906 source models to understand stress transfer to the 1911 site. In contrast to the static stress shadow, the peak dynamic Coulomb stress imparted by the 1906 rupture promoted failure at the site of the 1911 earthquake by 1.4-5.8 bar. Perhaps because the sample is small and the aftershocks are poorly located, we find no correlation of 1906 aftershock frequency or magnitude with the peak dynamic stress, although all aftershocks sustained a calculated dynamic stress of ???3 bar. Just 20 km to the south of the 1911 epicenter, we find that surface creep of the Calaveras fault at Hollister paused for ~17 yr after 1906, about the expected delay for the calculated static stress drop imparted by the 1906 earthquake when San Andreas fault postseismic creep and viscoelastic relaxation are included. Thus, the 1911 earthquake may have been promoted by the transient dynamic stresses, while Calaveras fault creep 20 km to the south appears to have been inhibited by the static stress changes.

  4. The Effect of Focal Distance, Age, and Brightness on Near-Field Augmented Reality Depth Matching

    OpenAIRE

    Singh, Gujot; Ellis, Stephen R.; Swan II, J. Edward

    2017-01-01

    Many augmented reality (AR) applications operate within near-field reaching distances, and require matching the depth of a virtual object with a real object. The accuracy of this matching was measured in three experiments, which examined the effect of focal distance, age, and brightness, within distances of 33.3 to 50 cm, using a custom-built AR haploscope. Experiment I examined the effect of focal demand, at the levels of collimated (infinite focal distance), consistent with other depth cues...

  5. FoCaLiZe: Inside an F-IDE

    Directory of Open Access Journals (Sweden)

    François Pessaux

    2014-04-01

    Full Text Available For years, Integrated Development Environments have demonstrated their usefulness in order to ease the development of software. High-level security or safety systems require proofs of compliance to standards, based on analyses such as code review and, increasingly nowadays, formal proofs of conformance to specifications. This implies mixing computational and logical aspects all along the development, which naturally raises the need for a notion of Formal IDE. This paper examines the FoCaLiZe environment and explores the implementation issues raised by the decision to provide a single language to express specification properties, source code and machine-checked proofs while allowing incremental development and code reusability. Such features create strong dependencies between functions, properties and proofs, and impose an particular compilation scheme, which is described here. The compilation results are runnable OCaml code and a checkable Coq term. All these points are illustrated through a running example.

  6. Third-generation intelligent IR focal plane arrays

    Science.gov (United States)

    Caulfield, H. John; Jack, Michael D.; Pettijohn, Kevin L.; Schlesselmann, John D.; Norworth, Joe

    1998-03-01

    SBRC is at the forefront of industry in developing IR focal plane arrays including multi-spectral technology and '3rd generation' functions that mimic the human eye. 3rd generation devices conduct advanced processing on or near the FPA that serve to reduce bandwidth while performing needed functions such as automatic target recognition, uniformity correction and dynamic range enhancement. These devices represent a solution for processing the exorbitantly high bandwidth coming off large area FPAs without sacrificing systems sensitivity. SBRC's two-color approach leverages the company's HgCdTe technology to provide simultaneous multiband coverage, from short through long wave IR, with near theoretical performance. IR systems that are sensitive to different spectral bands achieve enhanced capabilities for target identification and advanced discrimination. This paper will provide a summary of the issues, the technology and the benefits of SBRC's third generation smart and two-color FPAs.

  7. Focal and optional ergative marking in Warrwa (Kimberley, Western Australia)

    DEFF Research Database (Denmark)

    McGregor, William

    2006-01-01

    Warrwa is a morphologically ergative language with three ergative markers, -na, -ma, and-nma. Intriguingly, while -ma is almost in complementary distribution with both -na and -nma, the latter pair are in "free variation'', and either can replace the other anywhere. When it is used, however, -nma...... accords prominence to an Agent (i.e. transitive subject), singling it out asboth unexpected and highly agentive; accordingly it can be considered to be a focal ergative marker.By contrast, -na is an ordinary ergative marker, with no pragmatic components to its meaning; the situation for -ma is uncertain....... The story is complicated further by the fact that ergative markers are occasionally omitted from Agent NPs. This ‘"optional'' ergative marking is not random: it defocusses the Agent, indicating that it is both expected and low in agentivity. Much of the paper is taken up by presentation of evidence for...

  8. Spatial noise in staring IR focal plane arrays

    International Nuclear Information System (INIS)

    Scribner, D.A.; Kruer, M.R.; Sarkady, K.; Gridley, J.C.

    1988-01-01

    Problems with nonuniformity correction algorithms due to nonlinear pixel response and 1/f noise have been shown previously to cause spatial noise which can be significantly greater than temporal noise. The residual spatial noise after correction cannot be reduced with time averaging. Because of spatial noise the sensitivity of staring FPA sensors is often less than predicted on the basis of the temporal noise of the individual elements. A review is given of methods for measuring and analyzing spatial noise (after nonuniformity correction) in staring infrared focal plane arrays. Automated measurement techniques are described briefly, including necessary equipment and data reduction procedures. An example of spatial noise measurements is given using a staring InSb Charge Injection Device (CID) array

  9. Digitally switchable multi-focal lens using freeform optics.

    Science.gov (United States)

    Wang, Xuan; Qin, Yi; Hua, Hong; Lee, Yun-Han; Wu, Shin-Tson

    2018-04-16

    Optical technologies offering electrically tunable optical power have found a broad range of applications, from head-mounted displays for virtual and augmented reality applications to microscopy. In this paper, we present a novel design and prototype of a digitally switchable multi-focal lens (MFL) that offers the capability of rapidly switching the optical power of the system among multiple foci. It consists of a freeform singlet and a customized programmable optical shutter array (POSA). Time-multiplexed multiple foci can be obtained by electrically controlling the POSA to switch the light path through different segments of the freeform singlet rapidly. While this method can be applied to a broad range of imaging and display systems, we experimentally demonstrate a proof-of-concept prototype for a multi-foci imaging system.

  10. Alport's syndrome with focal segmental glomerulosclerosis lesion - Pattern to recognize.

    Science.gov (United States)

    Alsahli, Afnan A; Alshahwan, Sara I; Alotaibi, Amal O; Alsaad, Khaled O; Aloudah, Nourah; Farooqui, Mahfooz; Al Sayyari, Abdullah A

    2018-01-01

    The association between Alport's syndrome (AS) and focal segmental glomerulosclerosis (FSGS) in the same patient is complex and rarely reported. We report a case of a 42-year-old male presenting with proteinuria, microscopic hematuria, elevated serum creatinine and hypertension with unremarkable physical examination apart from obesity. The renal biopsy showed well-established FSGS pattern of injury with mild interstitial fibrosis and tubular atrophy, while the electron microscopic examination demonstrated glomerular basement membranes (GBM) changes compatible with AS. AS can be complicated by segmental glomerular scarring, which can mimic primary FSGS, while familial FSGS can result from mutations in collagen IV network of the GBM. This overlap can complicate histopathological interpretation of renal biopsy, which should be accompanied by mutational analysis for accurate diagnosis and proper therapeutic intervention.

  11. Secondary Focal Segmental Glomerulosclerosis: From Podocyte Injury to Glomerulosclerosis

    Directory of Open Access Journals (Sweden)

    Jae Seok Kim

    2016-01-01

    Full Text Available Focal segmental glomerulosclerosis (FSGS is a common cause of proteinuria and nephrotic syndrome leading to end stage renal disease (ESRD. There are two types of FSGS, primary (idiopathic and secondary forms. Secondary FSGS shows less severe clinical features compared to those of the primary one. However, secondary FSGS has an important clinical significance because a variety of renal diseases progress to ESRD thorough the form of secondary FSGS. The defining feature of FSGS is proteinuria. The key event of FSGS is podocyte injury which is caused by multiple factors. Unanswered questions about how these factors act on podocytes to cause secondary FSGS are various and ill-defined. In this review, we provide brief overview and new insights into FSGS, podocyte injury, and their potential linkage suggesting clues to answer for treatment of the disease.

  12. Focal hypermobility observed in cervical arthroplasty with Mobi-C.

    Science.gov (United States)

    Kerferd, Jack William; Abi-Hanna, David; Phan, Kevin; Rao, Prashanth; Mobbs, Ralph J

    2017-12-01

    In recent decades cervical arthroplasty, or cervical disc replacement, has been steadily increasing in popularity as a procedure for the treatment of degenerative pathologies of the cervical spine. This is based on an evolving body of literature that documents superior outcomes in cervical disc replacement over fusion, for both single and double level pathologies, in well selected patients. One of the more recent and popular implants currently on the market is the Mobi-C cervical artificial disc (LDR Medical; Troyes, France). In this paper we report on two cases where focal hypermobility was observed following total disc replacement using the Mobi-C cervical artificial disc. This is followed by a discussion as to potential contributing factors to this hypermobility in relation to both implant design, and operative technique, suggesting potential changes that might prevent this in future patients.

  13. Botulinum toxin for treatment of the focal dystonia.

    Science.gov (United States)

    Nakamura, Yusaku

    2017-07-29

    Dystonia is defined as a movement disorder characterized by sustained or intermittent muscles contraction causing abnormal, often repetitive, movements, postures, or both. Dystonic movements are typically patterned and twisting, and may be tremulous. The precis diagnosis of dystonia is difficult for physicians because neurological brain imaging does not provide enough practical information. The diagnosis is depend on clinical experience of physicians. Botulinum toxin treatment is the accepted standard of care for patients with focal dystonia. Botulinum toxin treatment results in significant improvement of decreasing the symptom of dystonia. The success of treatment is dependent on muscle selection for treating involved muscles. Usually performance of botulinum toxin treatment is injected according to clinical experience of surface anatomy or clinical location method. However, the benefit of guidance of botulinum toxin treatment is improve outcome in dystonia. Injection techniques with ultra sound echogram or EMG guidance to identify dystonic muscles can be more benefit for patients.

  14. A Clinicopathologic Study of Children with Idiopathic Focal Segmental Glomerulosclerosis.

    Science.gov (United States)

    Nickavar, Azar; Rahbar, Mahtab

    2016-01-01

    There is little information about the clinicopathological correlations of focal segmental glomerulosclerosis (FSGS) in children. Renal biopsies of 46 patients with primary FSGS were reviewed between 1994 and 2015. Clinical and laboratory findings were evaluated at the time of renal biopsy. Totally, not otherwise specified (NOS) was the most common pathologic variant in 38 patients. There was no correlation between age, gender, serum protein, urine protein, hematuria, and steroid response with five distinct pathologic variants and histopathologic lesions. Hgb level had a negative correlation to the glomerular hyalinosis, mesengial hypercellularity, mesengial deposition, and glomerular volume. Renal dysfunction and blood pressure had a significant positive association with the extent of tubular atrophy, interstitial fibrosis, synechiae in Bowman capsule, arteriolar hyalinosis, mononuclear infiltration, atherosclerosis, glomerular hyalinosis, mesengial hypercellularity, mesengial deposition, and glomerular sclerosis. In conclusion, serum creatinine and blood pressure were the significant predictors of histopathologic lesions in children with primary FSGS.

  15. Characterization of focal muscle compression under impact loading

    Science.gov (United States)

    Butler, B. J.; Sory, D. R.; Nguyen, T.-T. N.; Proud, W. G.; Williams, A.; Brown, K. A.

    2017-01-01

    In modern wars over 70% of combat wounds are to the extremities. These injuries are characterized by disruption and contamination of the limb soft tissue envelope. The extent of this tissue trauma and contamination determine the outcome of the extremity injury. In military injury, common post-traumatic complications at amputation sites include heterotopic ossification (formation of bone in soft tissue), and severe soft tissue and bone infections. We are currently developing a model of soft tissue injury that recreates pathologies observed in combat injuries. Here we present characterization of a controlled focal compression of the rabbit flexor carpi ulnaris (FCU) muscle group. The FCU was previously identified as a suitable site for studying impact injury because its muscle belly can easily be mobilized from the underlying bone without disturbing anatomical alignment in the limb. We show how macroscopic changes in tissue organization, as visualized using optical microscopy, can be correlated with data from temporally resolved traces of loading conditions.

  16. Homicidas juveniles en Bogotá, estudio de grupos focales

    Directory of Open Access Journals (Sweden)

    Franklin Escobar Córdoba

    2015-07-01

    Materiales y Métodos. Estudio cualitativo mediante técnica de grupos focales. Resultados. Se encontró como el factor de riesgo más implicado la disponibilidad y uso de armas. Otros  factores de riesgo determinantes de la conducta delincuencial afectan la disposición del joven homicida para tener un comportamiento criminal y las estrategias de control que son elegidas por el individuo, dichos factores son apreciados de maneras distintas por los jóvenes homicidas y los no homicidas Conclusión. Este estudio arroja información clave que puede ser utilizada en el diseño e implementación de estrategias para enfrentar el homicidio juvenil como problema de salud pública.

  17. Focal masses in a non-cirrhotic liver: The additional benefit of CEUS over baseline imaging

    Energy Technology Data Exchange (ETDEWEB)

    Chiorean, L., E-mail: lilichiorean@yahoo.com [Sino-German Research Center of Ultrasound in Medicine, The First Affiliated Hospital of Zhengzhou University (China); Med. Klinik 2, Caritas Krankenhaus Bad Mergentheim, Uhlandstr. 7, D-97980 Bad Mergentheim (Germany); Département d’imagerie médicale, Clinique des Cévennes, 07100 Annonay (France); Cantisani, V., E-mail: vito.cantisani@uniroma1.it [Dipartimento di Scienze Radiologiche, Oncologiche, Anatomo-patologiche, Policlinico Umberto I, Univ. Sapienza, Roma (Italy); Jenssen, C., E-mail: C.Jenssen@khmol.de [Innere Medizin, Krankenhaus Märkisch Oderland, Prötzeler Chaussee 5, 15433 Strausberg (Germany); Sidhu, P.S., E-mail: paulsidhu@nhs.net [Department of Radiology, King' s College Hospital, Denmark Hill, London SE5 9RS, England (United Kingdom); Baum, U., E-mail: Ulrich.Baum@ckbm.de [Department of Radiology, Caritas Krankenhaus Bad Mergentheim, Uhlandstr. 7, D-97980 Bad Mergentheim (Germany); Dietrich, C.F., E-mail: christoph.dietrich@ckbm.de [Sino-German Research Center of Ultrasound in Medicine, The First Affiliated Hospital of Zhengzhou University (China); Med. Klinik 2, Caritas Krankenhaus Bad Mergentheim, Uhlandstr. 7, D-97980 Bad Mergentheim (Germany)

    2015-09-15

    Highlights: • Contrast-enhanced ultrasound in detection of focal liver lesions. • Contrast-enhanced ultrasound in characterization of focal liver lesions. • Contrast-enhanced ultrasound in differential diagnosis of focal liver lesions. • Contrast-enhanced ultrasound in final diagnosis of focal liver lesions. • Contrast-enhanced ultrasound in liver metastases screening. • Roles of cross-sectional imaging techniques for focal liver lesions assessment. • Advantages of contrast-enhanced ultrasound over other imaging procedures. - Abstract: Incidentally detected focal liver lesions are commonly encountered in clinical practice presenting a challenge in the daily department work flow. Guidelines for the management of incidental focal liver lesions have been published but comments, illustrations and recommendations regarding practical issues are crucial. The unique features of contrast-enhanced ultrasound in non-invasive assessment of focal liver lesion enhancement throughout the vascular phases in real-time has allowed an impressive improvement in the diagnostic accuracy of ultrasound. We highlight the additional benefit of contrast-enhanced ultrasound over conventional B-mode ultrasound imaging in detection, characterization, differential and final diagnosis of focal liver lesions, as well as for liver metastases screening. The current roles of cross-sectional imaging are explained in detail, with indications and limitations for each procedure. The advantages of CEUS, such as non-ionizing radiation exposure, cost benefits, non-iodinate contrast agents, and repeatability are also described ultimately improving patient management.

  18. Infrared detectors and focal plane arrays; Proceedings of the Meeting, Orlando, FL, Apr. 18, 19, 1990

    Science.gov (United States)

    Dereniak, Eustace L.; Sampson, Robert E.

    1990-09-01

    The papers contained in this volume provide an overview of recent advances and the current state of developments in the field of infrared detectors and focal plane arrays. Topics discussed include nickel silicide Schottky-barrier detectors for short-wavelength infrared applications; high performance PtSi linear and focal plane arrays; and multispectral band Schottky-barrier IRSSD for remote-sensing applications. Papers are also presented on the performance of an Insi hybrid focal array; characterization of IR focal plane test stations; GaAs CCD readout for engineered bandgap detectors; and fire detection system for aircraft cargo bays.

  19. Focal shift and faculae dimension of focused flat beam propagating in turbulent atmosphere

    International Nuclear Information System (INIS)

    Zhang Jianzhu; Li Youkuan; Zhang Feizhou; An Jianzhu

    2011-01-01

    Through theoretic analysis and numerical simulation,the focal shift of a focused flat beam propagating in turbulent atmosphere is studied. When a focused flat beam propagates in turbulent atmosphere, the effect of turbulence will induce the focal spot to move toward the transmitter. The turbulence is stronger and the diameter of transmitter is smaller, the measure of focal shift is larger. When adjusting the focus of transmitter and letting the focal spot of beam locate on detector, the laser intensity received by detector is not the strongest. The laser intensity will be the strongest if the focus of transmitter equals to the distance from transmitter to detector. (authors)

  20. Protein kinase C, focal adhesions and the regulation of cell migration

    DEFF Research Database (Denmark)

    Fogh, Betina S; Multhaupt, Hinke A B; Couchman, John Robert

    2014-01-01

    in their intracellular compartment. Among these are tyrosine kinases, which have received a great deal of attention, whereas the serine/threonine kinase protein kinase C has received much less. Here the status of protein kinase C in focal adhesions and cell migration is reviewed, together with discussion of its roles...... and adhesion turnover. Focal adhesions, or focal contacts, are widespread organelles at the cell-matrix interface. They arise as a result of receptor interactions with matrix ligands, together with clustering. Recent analysis shows that focal adhesions contain a very large number of protein components...

  1. CONSUMER PREFERENCES FOR SCANNING MODALITY TO DIAGNOSE FOCAL LIVER LESIONS.

    Science.gov (United States)

    Whitty, Jennifer; Filby, Alexandra; Smith, Adam B; Carr, Louise M

    2015-01-01

    Differences in the process of using liver imaging technologies might be important to patients. This study aimed to investigate preferences for scanning modalities used in diagnosing focal liver lesions. A discrete choice experiment was administered to 504 adults aged 25 ≥years. Respondents made repeated choices between two hypothetical scans, described according to waiting time for scan and results, procedure type, the chance of minor side-effects, and whether further scanning procedures were likely to be required. Choice data were analyzed using mixed-logit models with respondent characteristics used to explain preference heterogeneity. Respondents preferred shorter waiting times, the procedure to be undertaken with a handheld scanner on a couch instead of within a body scanner, no side-effects, and no follow–up scans (p≤.01). The average respondent was willing to wait an additional 2 weeks for the scan if it resulted in avoiding side-effects, 1.5 weeks to avoid further procedures or to be told the results immediately, and 1 week to have the scan performed on a couch with a handheld scanner. However, substantial heterogeneity was observed in the strength of preference for desirable imaging characteristics. An average individual belonging to a general population sub–group most likely to require imaging to characterize focal liver lesions in the United Kingdom would prefer contrast–enhanced ultrasound over magnetic resonance imaging or computed tomography. Insights into the patient perspective around differential characteristics of imaging modalities have the potential to be used to guide recommendations around the use of these technologie

  2. MRI of experimental focal cerebral ischemia in sheep

    International Nuclear Information System (INIS)

    Foerschler, A.; Waldmin, D.; Gille, U.; Leipzig Univ.; Zimmer, C.

    2007-01-01

    Purpose: With respect to the specific characteristic of rete mirabile epidurale rostrale in sheep, the aim of this study was to investigate the use of time of flight (TOF) magnetic resonance angiography (MRA) to observe vascular anatomy and to validate MCA occlusion in a new model of experimental focal cerebral ischemia by permanent middle cerebral artery (MCA) occlusion in sheep (designed to study stroke therapy using autologous stem cells from umbilical cord blood). Furthermore, we wanted to assess the extent and natural time course of ischemic focal brain injury in sheep using functional and morphological magnetic resonance imaging (MRI). Materials and Method: 13 Merino sheep were examined. In 4 of the animals all, in 5 sheep 1 or 2 MCA branches were occluded and in 1 one case touched (sham operation). 4 controls did not undergo a surgical procedure. 23 MRI sessions were performed in 10 sheep. These sessions included T1, T2, T2 * sequences, diffusion-weighted imaging (DWI) and TOF MRA before and 2 - 46 days after the onset of stroke using a 1.5T clinical MR scanner. Corrosion casts of the cerebral arteries of 3 sheep were prepared and compared to MRA. Results: The MRA visualized the vessel anatomy or occlusion distal to the rete mirabile. Anatomical variants concerning the variant origin of the MCA and inconstant arteria choroidea rostralis and communicans rostralis were revealed. Sheep with occluded left MCA showed space occupying lesions with a drop in ADC values. Depending on the number of preserved MCA branches (0; 1; 2), highly significant (p < 0.001) differences in lesion size (21 ± 5.7; 13; 1.7 ± 1.3 ml) could be found. No indication of ischemia but minimal contusion damage was observed in the sham operated animal. (orig.)

  3. Crystal Structure of the FERM Domain of Focal Adhesion Kinase

    International Nuclear Information System (INIS)

    Ceccarelli, D.; Song, H.; Poy, F.; Schaller, M.; Eck, M.

    2006-01-01

    Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that localizes to focal adhesions in adherent cells. Through phosphorylation of proteins assembled at the cytoplasmic tails of integrins, FAK promotes signaling events that modulate cellular growth, survival, and migration. The amino-terminal region of FAK contains a region of sequence homology with band 4.1 and ezrin/radixin/moesin (ERM) proteins termed a FERM domain. FERM domains are found in a variety of signaling and cytoskeletal proteins and are thought to mediate intermolecular interactions with partner proteins and phospholipids at the plasma membrane and intramolecular regulatory interactions. Here we report two crystal structures of an NH2-terminal fragment of avian FAK containing the FERM domain and a portion of the regulatory linker that connects the FERM and kinase domains. The tertiary folds of the three subdomains (F1, F2, and F3) are similar to those of known FERM structures despite low sequence conservation. Differences in the sequence and relative orientation of the F3 subdomain alters the nature of the interdomain interface, and the phosphoinositide binding site found in ERM family FERM domains is not present in FAK. A putative protein interaction site on the F3 lobe is masked by the proximal region of the linker. Additionally, in one structure the adjacent Src SH3 and SH2 binding sites in the linker associate with the surfaces of the F3 and F1 lobes, respectively. These structural features suggest the possibility that protein interactions of the FAK FERM domain can be regulated by binding of Src kinases to the linker segment

  4. Surveillance following Focal Therapy interventions Seguimiento tras el tratamiento focal en el cáncer de próstata localizado

    NARCIS (Netherlands)

    Postema, A. W.; Catellani, M.; Scheltema, M. J. V.; van den Bos, W.; de la Rosette, J. J. M. C. H.

    2016-01-01

    Focal therapy (FT) is a tissuesparing treatment paradigm for localized prostate cancer (PCa) with the potential to improve functional outcomes while maintaining oncologic safety. This paper aims to provide an overview of important considerations and practical recommendations relating to the

  5. Tiechanshan-Tunghsiao anticline earthquake analysis: Implications for northwestern Taiwan potential carbon dioxide storage site seismic hazard

    Directory of Open Access Journals (Sweden)

    Ruey-Juin Rau

    2017-01-01

    Full Text Available We analyze the seismicity and earthquake focal mechanisms beneath the Tiechanshan-Tunghsiao (TCS-TH anticline over the last two decades for seismic hazard evaluation of a potential carbon dioxide storage site in northwestern Taiwan. Seismicity in the TCS-TH anticline indicates both spatial and temporal clustering at a depth range of 7 - 12 km. Thirteen 3.0 ≤ ML ≤ 5.2 earthquake focal mechanisms show a combination of thrust, strike-slip, and normal faulting mechanisms under the TCS-TH anticline. A 1992 ML 5.2 earthquake with a focal depth of ~10 km, the largest event ever recorded beneath the TCS-TH anticline during the last two decades, has a normal fault mechanism with the T-axis trending NNE-SSW and nodal planes oriented NNW-SSE, dipping either gently to the NNE or steeply to the SSW. Thrust fault mechanisms that occurred with mostly E-W or NWW-SEE striking P-axes and strike-slip faulting events indicate NWW-SEE striking P-axes and NNE-SSW trending T-axes, which are consistent with the regional plate convergence direction. For the strike-slip faulting events, if we take the N-S or NNW-SSE striking nodal planes as the fault planes, the strike-slip faults are sinistral motions and correspond to the Tapingting fault, which is a strike-slip fault reactivated from the inherited normal fault and intersects the Tiechanshan and Tunghsiao anticlines.

  6. Focal spot motion of linear accelerators and its effect on portal image analysis

    NARCIS (Netherlands)

    Sonke, Jan-Jakob; Brand, Bob; van Herk, Marcel

    2003-01-01

    The focal spot of a linear accelerator is often considered to have a fully stable position. In practice, however, the beam control loop of a linear accelerator needs to stabilize after the beam is turned on. As a result, some motion of the focal spot might occur during the start-up phase of

  7. Statin-induced focal myositis of the upper extremity. A report of two cases

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, M., E-mail: wagner.radiologie@herzchirurgie.de [Department of Radiology, Herz- und Gefaessklinik GmbH, Salzburger Leite 1, D-97616 Bad Neustadt an der Saale (Germany); Muehldorfer-Fodor, M.; Prommersberger, K.J. [Department of Handsurgery, Herz- und Gefaessklinik GmbH, Bad Neustadt an der Saale (Germany); Schmitt, R. [Department of Radiology, Herz- und Gefaessklinik GmbH, Salzburger Leite 1, D-97616 Bad Neustadt an der Saale (Germany)

    2011-02-15

    Statins are widely used to lower increased cholesterol levels with the aim to prevent major cardiovascular events. However, they bare the risk of myotoxic side effects. We report on two patients with focal weakness and pain in the upper extremities. In both patients, abnormal MRI signal heights in the muscle groups involved were indicative of the final diagnosis of focal myositis during statin therapy.

  8. Super-resolution links vinculin localization to function in focal adhesions.

    Science.gov (United States)

    Giannone, Grégory

    2015-07-01

    Integrin-based focal adhesions integrate biochemical and biomechanical signals from the extracellular matrix and the actin cytoskeleton. The combination of three-dimensional super-resolution imaging and loss- or gain-of-function protein mutants now links the nanoscale dynamic localization of proteins to their activation and function within focal adhesions.

  9. Collusion through Price Ceilings? In Search of a Focal-Point Effect

    NARCIS (Netherlands)

    Engelmann, D.; Müller, W.

    2008-01-01

    With this study we resume the search for a collusive focal-point effect of price ceilings in laboratory markets. We argue that market conditions in previous studies were unfavorable for collusion which may have been responsible for not finding such a focal-point effect. Our design aims at maximizing

  10. Collusion through price ceilings? In search of a focal-point effect

    NARCIS (Netherlands)

    Engelmann, D.; Müller, W.

    2011-01-01

    We resume the search for a collusive focal-point effect of price ceilings in laboratory markets. We argue that market conditions in previous studies were unfavorable for collusion which may have been responsible for not finding such a focal-point effect. Our design aims at maximizing the likelihood

  11. Statin-induced focal myositis of the upper extremity. A report of two cases

    International Nuclear Information System (INIS)

    Wagner, M.; Muehldorfer-Fodor, M.; Prommersberger, K.J.; Schmitt, R.

    2011-01-01

    Statins are widely used to lower increased cholesterol levels with the aim to prevent major cardiovascular events. However, they bare the risk of myotoxic side effects. We report on two patients with focal weakness and pain in the upper extremities. In both patients, abnormal MRI signal heights in the muscle groups involved were indicative of the final diagnosis of focal myositis during statin therapy.

  12. Focal vitiligo: long-term follow-up of 52 cases

    NARCIS (Netherlands)

    Lommerts, J. E.; Schilder, Y.; de Rie, M. A.; Wolkerstorfer, A.; Bekkenk, M. W.

    2016-01-01

    Focal vitiligo is characterized by depigmented patches located in a small area without a typical segmental distribution. Focal vitiligo is classified as an undetermined type of vitiligo, and a more definitive diagnosis can be made when the lesions have not evolved into non-segmental or segmental

  13. The large 1956 earthquake in the South Aegean: Macroseismic field configuration, faulting, and neotectonics of Amorgos Island

    Science.gov (United States)

    Papadopoulos, Gerassimos A.; Pavlides, Spyros B.

    1992-10-01

    New field observations of the seismic intensity distribution of the large (M s = 7.4) South Aegean (Amorgos) earthquake of 9 July 1956 are presented. Interpretations based on local ground conditions, structural properties of buildings and peculiarities of the rupture process lead to a re-evaluation of the macroseismic field configuration. This, together with the aftershock epicentral distribution, quite well defines the earthquake rupture zone, which trends NE-SW and coincides with the Amorgos Astypalea trough. The lateral extent of the rupture zone, however, is about 40% smaller than that predicted for Aegean earthquakes of M s = 7.4. This discrepancy could be attributed to sea-bottom topography changes, which seem to control the rupture terminations, and to relatively high stressdrop with respect to other Aegean earthquakes. Fault plane solutions obtained by several authors indicate either mainly normal faulting with a significant right-lateral strike-slip component or predominantly strike-slip motion. The neotectonism of Amorgos Island, based on new field observations, aerial photograph analysis and fault mechanisms, is consistent with the dip-slip interpretation. The neotectonic master fault of Amorgos and the 1956 seismic faulting appear to belong to the same tectonic phase (NE-SW strike and a southeasterly dip). However, the significant right-lateral strike-slip component supports the idea that the Amorgos region deviates from the simple description for pure extension in back-arc conditions.

  14. Fibrocystic change of the breast presenting as a focal lesion mimicking breast cancer in MR imaging.

    Science.gov (United States)

    Chen, Jeon-Hor; Nalcioglu, Orhan; Su, Min-Ying

    2008-12-01

    Focal fibrocystic change (FCC) of the breast is a rare form of FCC. Imaging presentations of focal FCC are not well known. This study aimed to analyze its MR imaging features. Eleven patients of pathology-proven focal FCC were retrospectively studied. Of the 11 patients, seven were mass (>or=5 mm), two showed multiple foci, and two were focus (Breast sonography suspected malignancy in seven patients (7/10, 70%). No statistically significant difference was found in the three diagnostic methods. In pathology, all 11 patients showed the typical pathological features of fibrocystic change, with mixed components of stromal fibrosis, cyst formation, apocrine metaplasia, adenosis, and/or focal sclerosing adenosis. In conclusion, MR imaging features of focal FCC usually present as a mass or focus lesion with rapid enhancement and washout kinetics that mimic a malignant breast lesion and lead to unnecessary operation, especially in patients with contralateral malignant breast cancer. (c) 2008 Wiley-Liss, Inc.

  15. Systematic study of the focal shift effect in planar plasmonic slit lenses

    International Nuclear Information System (INIS)

    Hu Bin; Wang Qijie; Zhang Ying

    2012-01-01

    In this paper, we systematically studied the focal shift effect in planar plasmonic slit lenses. Through theoretical derivations and numerical simulations, we found that there is a focal length shift between the traditional design model and the finite-difference time-domain simulations. The shift is not only dependent on the Fresnel number (FN) of the lens, like traditional dielectric lenses, determined by the lens width and the designed focal length, but also on the surface plasmon polariton (SPPs) interaction on the lens surfaces, dependent on the slit numbers. We also found that the FN-induced focal shift is predominant when FN 1. An approximated theoretical model is presented to estimate the focal shift of plasmonic slit lens with FN < 1. (paper)

  16. Focal thyroid incidentalomas identified with whole-body FDG-PET warrant further investigation.

    LENUS (Irish Health Repository)

    Prichard, R S

    2012-02-01

    Fluorodeoxyglucose (FDG) whole body positron emission computed tomography (PET-CT) detects clinically occult malignancy. The aim of this study was to assess the prevalence and significance of focal thyroid 18F - fluorodeoxyglucose uptake. A retrospective review of all patients who had FDG PET-CT examinations, in a single tertiary referral centre was performed. PET scan findings and the final pathological diagnosis were collated. 2105 scans were reviewed. Focal uptake was identified in 35 (1.66%) patients. Final surgical histology was available on eight patients, which confirmed papillary carcinoma in four (20%) patients and lymphoma and metastatic disease in two patients respectively. This gave an overall malignancy rate in focal thyroid uptake of at least 33%. Thyroid incidentalomas occurred with a frequency of 2.13%, with an associated malignancy rate of at least 33% in focal thyroid uptake. The high malignancy rate associated with focal thyroid uptake mandates further investigation in medically fit patients.

  17. Focal spot motion of linear accelerators and its effect on portal image analysis

    International Nuclear Information System (INIS)

    Sonke, Jan-Jakob; Brand, Bob; Herk, Marcel van

    2003-01-01

    The focal spot of a linear accelerator is often considered to have a fully stable position. In practice, however, the beam control loop of a linear accelerator needs to stabilize after the beam is turned on. As a result, some motion of the focal spot might occur during the start-up phase of irradiation. When acquiring portal images, this motion will affect the projected position of anatomy and field edges, especially when low exposures are used. In this paper, the motion of the focal spot and the effect of this motion on portal image analysis are quantified. A slightly tilted narrow slit phantom was placed at the isocenter of several linear accelerators and images were acquired (3.5 frames per second) by means of an amorphous silicon flat panel imager positioned ∼0.7 m below the isocenter. The motion of the focal spot was determined by converting the tilted slit images to subpixel accurate line spread functions. The error in portal image analysis due to focal spot motion was estimated by a subtraction of the relative displacement of the projected slit from the relative displacement of the field edges. It was found that the motion of the focal spot depends on the control system and design of the accelerator. The shift of the focal spot at the start of irradiation ranges between 0.05-0.7 mm in the gun-target (GT) direction. In the left-right (AB) direction the shift is generally smaller. The resulting error in portal image analysis due to focal spot motion ranges between 0.05-1.1 mm for a dose corresponding to two monitor units (MUs). For 20 MUs, the effect of the focal spot motion reduces to 0.01-0.3 mm. The error in portal image analysis due to focal spot motion can be reduced by reducing the applied dose rate

  18. Proximal focal femoral deficiency: evaluation by MR imaging

    International Nuclear Information System (INIS)

    Biko, David M.; Davidson, Richard; Pena, Andres; Jaramillo, Diego

    2012-01-01

    Proximal focal femoral deficiency (PFFD) is a rare congenital anomaly characterized by abnormal development of the proximal femur. The most common radiographic classification (Aitken) does not evaluate the cartilaginous and soft-tissue abnormalities. To demonstrate MR findings of PFFD focusing on features not seen with radiographs. Nine MR examinations of the hip and femurs of seven children with PFFD were retrospectively reviewed. Imaging was quantitatively and qualitatively assessed comparing the affected limb to the contralateral limb and age-matched controls. The children were classified via the Aitken classification. All children had at least mild acetabular dysplasia, and one type D patient had no acetabulum. MR demonstrated that 4/6 children had labral hypertrophy with a decreased distance from the greater trochanter to the acetabular rim, suggesting impingement (P < 0.05). The proximal femoral physis was abnormal in all cases. The connection between the femoral head and shaft if present was fibrous or fibrocartilaginous. MRI can help in evaluation of PFFD by defining the anatomy. MR demonstrates features of the acetabulum and cartilaginous femoral epiphysis and depicts ligamentous abnormalities of the knee. (orig.)

  19. Corrugated Quantum Well Infrared Photodetector Focal Plane Array Test Results

    Science.gov (United States)

    Goldberg, A.; Choi, K. K.; Das, N. C.; La, A.; Jhabvala, M.

    1999-01-01

    The corrugated quantum-well infrared photodetector (C-QWIP) uses total internal reflection to couple normal incident light into the optically active quantum wells. The coupling efficiency has been shown to be relatively independent of the pixel size and wavelength thus making the C-QWIP a candidate for detectors over the entire infrared spectrum. The broadband coupling efficiency of the C-QWIP makes it an ideal candidate for multiwavelength detectors. We fabricated and tested C-QWIP focal plane arrays (FPAs) with cutoff wavelengths of 11.2 and 16.2 micrometers. Each FPA has 256 x 256 pixels that are bump-bonded to a direct injection readout circuit. Both FPAs provided infrared imagery with good aesthetic attributes. For the 11.2-micrometers FPA, background-limited performance (BLIP) was observed at 60 K with f/3 optics. For the 16.2-micrometers FPA, BLIP was observed at 38 K. Besides the reduction of dark current in C-QWIP structures, the measured internal quantum efficiency (eta) remains to be high. The values for responsivity and quantum efficiency obtained from the FPA results agree well with those measured for single devices.

  20. Focal Segmental Glomerulosclerosis in Related Miniature Schnauzer Dogs.

    Science.gov (United States)

    Yau, Wilson; Mausbach, Lisa; Littman, Meryl P; Cianciolo, Rachel E; Brown, Cathy A

    2018-03-01

    Focal segmental glomerulosclerosis (FSGS) recently has been recognized as a common cause of proteinuria in dogs in general, and in Miniature Schnauzer dogs in particular. This study describes the morphologic features present in the kidneys of 8 related proteinuric Miniature Schnauzer dogs. The FSGS, characterized by solidification of portions of the capillary tuft, affected 32% to 49% of examined glomeruli in these dogs. Synechiae, often accompanied by hyalinosis, were present in 13% to 54% of glomeruli and were more prevalent in older dogs. Seven of 8 dogs had arteriolar hyalinosis. Ultrastructurally, all dogs had evidence of a podocytopathy in the absence of electron-dense deposits, glomerular basement membrane splitting, or fibrils. All dogs had multifocal to extensive podocyte foot process effacement. Other podocyte changes included microvillous transformation, the presence of vacuoles or protein resorption droplets, cytoplasmic electron-dense aggregates, and occasional binucleation. Variable amounts of intraglomerular lipid were present in all dogs. All dogs were proteinuric, with measured values for the urine protein-to-creatinine ratio ranging from 1.2 to 6.5. Azotemia was mild to absent and dogs were euthanatized at 5.1 to 14 years of age, in all cases due to nonrenal diseases. The underlying cause of FSGS in these Miniature Schnauzer dogs has yet to be determined, but contributors likely include genetic podocytopathy, lipid abnormalities, and glomerular hypertension.

  1. Physical Limitations To Nonuniformity Correction In IR Focal Plane Arrays

    Science.gov (United States)

    Scribner, D. A.; Kruer, M. R.; Gridley, J. C.; Sarkady, K.

    1988-05-01

    Simple nonuniformity correction algorithms currently in use can be severely limited by nonlinear response characteristics of the individual pixels in an IR focal plane array. Although more complicated multi-point algorithms improve the correction process they too can be limited by nonlinearities. Furthermore, analysis of single pixel noise power spectrums usually show some level of 1 /f noise. This in turn causes pixel outputs to drift independent of each other thus causing the spatial noise (often called fixed pattern noise) of the array to increase as a function of time since the last calibration. Measurements are presented for two arrays (a HgCdTe hybrid and a Pt:Si CCD) describing pixel nonlinearities, 1/f noise, and residual spatial noise (after nonuniforming correction). Of particular emphasis is spatial noise as a function of the lapsed time since the last calibration and the calibration process selected. The resulting spatial noise is examined in terms of its effect on the NEAT performance of each array tested and comparisons are made. Finally, a discussion of implications for array developers is given.

  2. Efficacy of MRI in classifying proximal focal femoral deficiency

    International Nuclear Information System (INIS)

    Maldjian, C.; Patel, T.Y.; Klein, R.M.; Smith, R.C.

    2007-01-01

    To evaluate the efficacy of MRI in classifying PFFD and to compare MRI to radiographic classification of PFFD. Radiographic and MRI classification of the cases was performed utilizing the Amstutz classification system. Retrospective evaluation of radiographs and MRI exams in nine hips of eight patients with proximal focal femoral deficiency was performed by two radiologists. The cases were classified by radiographs as Amstutz 1: n=3, Amstutz 3: n=3, Amstutz 4: n=1 and Amstutz 5: n=2. The classifications based on MRI were Amstutz 1: n=6, Amstutz 2: n=1, Amstutz 3: n=0, Amstutz 4: n=2 and Amstutz 5: n=0. Three hips demonstrated complete agreement. There were six discordant hips. In two of the discordant cases, follow-up radiographs of 6 months or greater intervals were available and helped to confirm MRI findings. Errors in radiographic evaluation consisted of overestimating the degree of deficiency. MRI is more accurate than radiographic evaluation for the classification of PFFD, particularly early on, prior to the ossification of cartilaginous components in the femurs. Since radiographic evaluation tends to overestimate the degree of deficiency, MRI is a more definitive modality for evaluation of PFFD. (orig.)

  3. Modulation Transfer Function of Infrared Focal Plane Arrays

    Science.gov (United States)

    Gunapala, S. D.; Rafol, S. B.; Ting, D. Z.; Soibel, A.; Hill, C. J.; Khoshakhlagh, A.; Liu, J. K.; Mumolo, J. M.; Hoglund, L.; Luong, E. M.

    2015-01-01

    Modulation transfer function (MTF) is the ability of an imaging system to faithfully image a given object. The MTF of an imaging system quantifies the ability of the system to resolve or transfer spatial frequencies. In this presentation we will discuss the detail MTF measurements of 1024x1024 pixels mid -wavelength and long- wavelength quantum well infrared photodetector, and 320x256 pixels long- wavelength InAs/GaSb superlattice infrared focal plane arrays (FPAs). Long wavelength Complementary Barrier Infrared Detector (CBIRD) based on InAs/GaSb superlattice material is hybridized to recently designed and fabricated 320x256 pixel format ROIC. The n-type CBIRD was characterized in terms of performance and thermal stability. The experimentally measured NE delta T of the 8.8 micron cutoff n-CBIRD FPA was 18.6 mK with 300 K background and f/2 cold stop at 78K FPA operating temperature. The horizontal and vertical MTFs of this pixel fully delineated CBIRD FPA at Nyquist frequency are 49% and 52%, respectively.

  4. Proximal focal femoral deficiency: evaluation by MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Biko, David M. [National Naval Medical Center, Department of Radiology, Bethesda, MD (United States); Uniformed Services University of Health Sciences, Department of Radiology and Radiological Sciences, Bethesda, MD (United States); Davidson, Richard [The Children' s Hospital of Philadelphia, Department of Orthopedic Surgery, Philadelphia, PA (United States); Pena, Andres; Jaramillo, Diego [The Children' s Hospital of Philadelphia, Department of Radiology, Philadelphia, PA (United States)

    2012-01-15

    Proximal focal femoral deficiency (PFFD) is a rare congenital anomaly characterized by abnormal development of the proximal femur. The most common radiographic classification (Aitken) does not evaluate the cartilaginous and soft-tissue abnormalities. To demonstrate MR findings of PFFD focusing on features not seen with radiographs. Nine MR examinations of the hip and femurs of seven children with PFFD were retrospectively reviewed. Imaging was quantitatively and qualitatively assessed comparing the affected limb to the contralateral limb and age-matched controls. The children were classified via the Aitken classification. All children had at least mild acetabular dysplasia, and one type D patient had no acetabulum. MR demonstrated that 4/6 children had labral hypertrophy with a decreased distance from the greater trochanter to the acetabular rim, suggesting impingement (P < 0.05). The proximal femoral physis was abnormal in all cases. The connection between the femoral head and shaft if present was fibrous or fibrocartilaginous. MRI can help in evaluation of PFFD by defining the anatomy. MR demonstrates features of the acetabulum and cartilaginous femoral epiphysis and depicts ligamentous abnormalities of the knee. (orig.)

  5. The spreading of focal brain edema induced by ultraviolet irradiation

    International Nuclear Information System (INIS)

    Ferszt, R.; Neu, S.; Cervos-Navarro, J.; Sperner, J.

    1978-01-01

    Focal brain edema limited to one cerebral hemisphere was produced by ultraviolet irradiation of the exposed cortex. Tissue water content was determined by the gravimetric method which allows microsampling. Therefore, the spread of edema around the small necrotic area be mapped more precisely than by determination of dry weight which calls for larger samples. As early as 30 min after irradiation, hyperemia and swelling of the brain are observed under the operating microscope. This correlates with venous stasis, hyperemia, and broadened perivascular spaces around venules and large capillaries accompanied by a marked rise in the specific weigth of the tissue. After 4h an edema front can be observed spreading from the perinerotic zone in which there is a marked rise in endothelial cell vesicular activity. Edema reaches maximum levels in the deep white matter at 48h post irradiation with normalisation of the tissue water content after 96h. The velocity at which the edema front spreads from the cortex to the periventricular area lies in the range of 0.25mm/h. Edema reabsorption coincides with signs of retrograde micropinocytosis in endothelial cells. (orig./AJ) [de

  6. MRI findings of multiple focal nodular hyperplasia of the liver

    International Nuclear Information System (INIS)

    Wang Xin; Yu Qingtai; Jing Yu; Wang Haiyi; Pan Jingjing; Duan Weidong; Wang Dianjun; Ye Huiyi

    2010-01-01

    Objective: To assess the diagnostic value of MRI on multiple focal nodular hyperplasia (FNH) of the liver. Methods: MR images of 9 cases with pathological-confirmed multiple FNH were retrospectively analyzed. MRI features of the lesions were correlated with pathological findings. Results: Multiple FNH was considered in all these 9 cases. Among them, the primary diagnosis was FNH in 5, hepatic adenoma in 3 and fibrolamellar hepatocellular carcinoma in 1 case. A total of 31 lesions were detected in the 9 cases. On T 2 WI, 19 lesions presented slightly high-signal intensity, and the other 12 presented iso-signal intensity. On T 1 WI, 12 lesions presented slightly low-signal intensity, 7 presented iso-signal intensity, and the other 12 presented high-signal intensity. On opposed-phase, the signal intensity of 1 lesion dropped unevenly. After bolus injection of contrast agent Gd-DTPA, in hepatic arterial phase 18 lesions showed mild to marked heterogeneous enhancement, 11 showed marked homogeneous enhancement, 1 showed moderate ring-like enhancement, and the last one did not have obvious enhancement. In portal venous and delayed phase, all the lesions turned to iso- or slightly high-signal intensity gradually. Sixteen of 31 lesions presented central scar, which demonstrated mild star-like enhancement in delayed phase. Conclusion: Multiple FNH presented certain MRI features, which contributed to the preoperative diagnosis. (authors)

  7. MSCT diagnosis and differential diagnosis of hepatic focal nodular hyperplasia

    International Nuclear Information System (INIS)

    Zhang Haitao; Xu Qinsha; Chen Yutang; Song Yupiao

    2011-01-01

    Objective: To evaluate the MSCT findings of focal nodular hyperplasia (FNH) of the liver, and to improve the diagnostic standard. Methods: The MSCT findings were analyzed retrospectively in 25 patients pathologically approved with FNH. All patients underwent 16 detector row spiral CT scanning with and without contrast enhancement. Results: 28 lesions were discovered by CT, with single lesion showed in 22 cases, 2 lesions showed in 3 cases. All lesions showed a solitary nodules or lobulated mass in the liver. On plain CT, FNH showed equal or slightly low density. In the arterial phase, 27 lesions were vigorously and homogeneously enhanced, except the central scars with CT value of 99∼149HU and the mean CT-number of 124 HU. 1 lesion ws enhanced inter-homogeneously. Tortuous and enlarged arteries were seen at the center or periphery in 8 of the 28 lesions. In the portal venous phase, 16 lesions remained slightly hyperdense, 8 lesions turned to isodense, and 1 lesion turned to slightly hypodense. The typical central scar was showed in 8 lesions and 2 lesions showed delayed enhancement. 21 cases were correctly diagnosed by MSCT, with the diagnostic accuracy of 84.0%. Conclusion: MSCT scanning can fully show the pathologic and the blood supplying characteristics of FNH. The typical FNH can be easily diagnosed by CT, while the atypical cases should be differentiated from hepatocellular carcinoma, hemangioma of liver, liver cell adenoma and fibrolamellar hepatocarcinoma. (authors)

  8. Cosmology Large Angular Scale Surveyor (CLASS) Focal Plane Development

    Science.gov (United States)

    Chuss, D. T.; Ali, A.; Amiri, M.; Appel, J.; Bennett, C. L.; Colazo, F.; Denis, K. L.; Dunner, R.; Essinger-Hileman, T.; Eimer, J.; hide

    2015-01-01

    The Cosmology Large Angular Scale Surveyor (CLASS) will measure the polarization of the Cosmic Microwave Background to search for and characterize the polarized signature of inflation. CLASS will operate from the Atacama Desert and observe approx.70% of the sky. A variable-delay polarization modulator provides modulation of the polarization at approx.10Hz to suppress the 1/f noise of the atmosphere and enable the measurement of the large angular scale polarization modes. The measurement of the inflationary signal across angular scales that spans both the recombination and reionization features allows a test of the predicted shape of the polarized angular power spectra in addition to a measurement of the energy scale of inflation. CLASS is an array of telescopes covering frequencies of 38, 93, 148, and 217 GHz. These frequencies straddle the foreground minimum and thus allow the extraction of foregrounds from the primordial signal. Each focal plane contains feedhorn-coupled transition-edge sensors that simultaneously detect two orthogonal linear polarizations. The use of single-crystal silicon as the dielectric for the on-chip transmission lines enables both high efficiency and uniformity in fabrication. Integrated band definition has been implemented that both controls the bandpass of the single-mode transmission on the chip and prevents stray light from coupling to the detectors.

  9. Sonographic pattern of focal nodular hyperplasia of the liver

    International Nuclear Information System (INIS)

    Majewski, A.; Gratz, K.F.; Broelsch, C.; Gebel, M.

    1984-01-01

    Focal nodular hyperplasia of the liver (FNH) is a histologically defined benign hepatic tumour, possibly associated with the use of oral contraceptives. The present study deals with the question whether FNH can be distinguished from other lesions of the liver by ultrasonography alone or by a combination of realtime sonography and radiologic procedures. Therefore 18 cases of FNH, 16 females and 2 males, are presented. We retrospectively reviewed the diagnostic results of real-time sonography, hepatic scintigraphy, computed tomography with dynamic CT-densitometry, and angiography on these 18 patients. Ultrasonography enables the identification of the lesion in all of the 18 cases. FNH appears to show varying degrees of echogenicity (slight hypoechoic in 6 cases, isoechoic in 6 cases, and slight hyperechoic in 4 cases). In most of the patients the tumour had similar acoustic characteristics at the surrounding normal liver. By ultrasonography alone there is no possible differentation of FNH from other hepatic tumours. Both the echo pattern of FNH and the results of the ultrasonically guided cytopuncture are unspecific. (orig.)

  10. [Pulmonary function in patients with focal pulmonary tuberculosis].

    Science.gov (United States)

    Nefedov, V B; Popova, L A; Shergina, E A

    2008-01-01

    Vital capacity (VC), forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/VC%, PEF, MEF25, MEF50, MEF75, TLC, TGV, pulmonary residual volume (PRV), Raw, Rin, Rcx, DLCO-SB, DLCO-SS/VA, PaO2, and PaCO2 were determined in 40 patients with focal pulmonary tuberculosis. Changes were found in lung volumes and capacities in 75%, impaired bronchial patency and pulmonary gas exchange dysfunction were in 57.5 and 25%, respectively. The lung volume and capacity changes appeared mainly as increased TGV and PRV; impaired bronchial patency presented as decreased MEF50, MEF75, and FEV1/VC%; pulmonary gas exchange dysfunction manifested itself as reduced DLCO-SB, PaO2, and PaCO2. The magnitude of the observed functional changes was generally slight. TGV and PRL increased up to 148-187 and 142-223% of the normal values, respectively; MEF50, MEF75, FEV1/VC%, and DLCO decreased to 59-24, 58-26, 78-57, and 78-67% of the normal values and PaO2 and PaCO2 did to 79-69 and 34-30 cm Hg.

  11. New Classification of Focal Cortical Dysplasia: Application to Practical Diagnosis

    Science.gov (United States)

    Bae, Yoon-Sung; Kang, Hoon-Chul; Kim, Heung Dong; Kim, Se Hoon

    2012-01-01

    Background and Purpose: Malformation of cortical development (MCD) is a well-known cause of drug-resistant epilepsy and focal cortical dysplasia (FCD) is the most common neuropathological finding in surgical specimens from drug-resistant epilepsy patients. Palmini’s classification proposed in 2004 is now widely used to categorize FCD. Recently, however, Blumcke et al. recommended a new system for classifying FCD in 2011. Methods: We applied the new classification system in practical diagnosis of a sample of 117 patients who underwent neurosurgical operations due to drug-resistant epilepsy at Severance Hospital in Seoul, Korea. Results: Among 117 cases, a total of 16 cases were shifted to other FCD subtypes under the new classification system. Five cases were reclassified to type IIIa and five cases were categorized as dual pathology. The other six cases were changed within the type I category. Conclusions: The most remarkable changes in the new classification system are the advent of dual pathology and FCD type III. Thus, it will be very important for pathologists and clinicians to discriminate between these new categories. More large-scale research needs to be conducted to elucidate the clinical influence of the alterations within the classification of type I disease. Although the new FCD classification system has several advantages compared to the former, the correlation with clinical characteristics is not yet clear. PMID:24649461

  12. Neural Substrates of Spontaneous Narrative Production in Focal Neurodegenerative Disease

    Science.gov (United States)

    Gola, Kelly A.; Thorne, Avril; Veldhuisen, Lisa D.; Felix, Cordula M.; Hankinson, Sarah; Pham, Julie; Shany-Ur, Tal; Schauer, Guido P.; Stanley, Christine M.; Glenn, Shenly; Miller, Bruce L.; Rankin, Katherine P.

    2016-01-01

    Conversational storytelling integrates diverse cognitive and socio-emotional abilities that critically differ across neurodegenerative disease groups and may have diagnostic relevance and predict anatomic changes. The present study employed mixed methods discourse and quantitative analyses to delineate patterns of storytelling across focal neurodegenerative disease groups, and to clarify the neuroanatomical contributions to common storytelling characteristics in these patients. Transcripts of spontaneous social interactions of 46 participants (15 behavioral variant frontotemporal dementia (bvFTD), 7 semantic variant primary progressive aphasia (svPPA), 12 Alzheimer's disease (AD), and 12 healthy older normal controls) were analysed for storytelling characteristics and frequency, and videos of the interactions were rated for patients' social attentiveness. Compared to controls, svPPAs also told more stories and autobiographical stories, and perseverated on aspects of self during storytelling. ADs told fewer autobiographical stories than NCs, and svPPAs and bvFTDs failed to attend to social cues. Storytelling characteristics were associated with a processing speed and mental flexibility, and voxel-based anatomic analysis of structural magnetic resonance imaging revealed that temporal organization, evaluations, and social attention correlated with atrophy corresponding to known intrinsic connectivity networks, including the default mode, limbic, salience, and stable task control networks. Differences in spontaneous storytelling among neurodegenerative groups elucidated diverse cognitive, socio-emotional, and neural contributions to narrative production, with implications for diagnostic screening and therapeutic intervention. PMID:26485159

  13. Unwinding focal segmental glomerulosclerosis [version 1; referees: 3 approved

    Directory of Open Access Journals (Sweden)

    Vasil Peev

    2017-04-01

    Full Text Available Focal segmental glomerulosclerosis (FSGS represents the most common primary glomerular disease responsible for the development of end-stage renal disease (ESRD in the United States (US. The disease progresses from podocyte injury to chronic kidney disease (CKD, ultimately leading to total nephron degeneration. Extensive basic science research has been conducted to unwind the mechanisms of FSGS and, with those insights, understand major contributors of CKD in general. As a result, several putative molecules and pathways have been studied, all implicated in the disease; some serve, in addition, as early biomarkers. The ongoing research is currently focusing on understanding how these molecules and pathways can interplay and be utilized as potential diagnostic and therapeutic targets. Among these molecules, the soluble urokinase plasminogen activating receptor (suPAR has been studied in detail, both clinically and from a basic science perspective. By now, it has emerged as the earliest and most robust marker of future CKD. Other circulating factors harming podocytes include anti-CD40 auto-antibody and possibly cardiotrophin-like cytokine factor-1. Understanding these factors will aid our efforts to ultimately cure FSGS and possibly treat a larger portion of CKD patients much more effectively.

  14. Inseguridad alimentaria en latinos de California: observaciones de grupos focales

    Directory of Open Access Journals (Sweden)

    Melgar-Quiñonez Hugo

    2003-01-01

    Full Text Available OBJETIVO: Estudiar la percepción y la experiencia sobre inseguridad alimentaria entre latinoamericanos de California, así como su interpretación de los insumos incluidos en la Escala de Seguridad Alimentaria. MATERIAL Y MÉTODOS: Entre noviembre y diciembre de 2000, en los condados californianos de Solano y San Joaquín, se efectuaron cuatro grupos focales, con 30 adultos de origen latinoamericano residentes allí. Los comentarios de los participantes fueron codificados por dos investigadores para determinar los temas principales, y fueron confrontados para verificar su convergencia. RESULTADOS: Las preguntas fueron bien comprendidas, no percibiéndose como ofensivas. El marco conceptual se confirmó como "proceso manejado" con diferentes niveles de severidad. Las causas de inseguridad alimentaria identificadas fueron: desempleo, alto costo de algunos alimentos y falta de información nutricional. La necesidad de educación nutricional fue una constante. CONCLUSIONES: Para interpretar datos nacionales de inseguridad alimentaria en latinoamericanos es esencial considerar su percepción particular de ese fenómeno.

  15. Focal Targeting of the Bacterial Envelope by Antimicrobial Peptides

    Directory of Open Access Journals (Sweden)

    Rafi eRashid

    2016-06-01

    Full Text Available Antimicrobial peptides (AMPs are utilized by both eukaryotic and prokaryotic organisms. AMPs such as the human beta defensins, human neutrophil peptides, human cathelicidin, and many bacterial bacteriocins are cationic and capable of binding to anionic regions of the bacterial surface. Cationic AMPs (CAMPs target anionic lipids (e.g. phosphatidylglycerol (PG and cardiolipins (CL in the cell membrane and anionic components (e.g. lipopolysaccharide (LPS and lipoteichoic acid (LTA of the cell envelope. Bacteria have evolved mechanisms to modify these same targets in order to resist CAMP killing, e.g. lysinylation of PG to yield cationic lysyl-PG and alanylation of LTA. Since CAMPs offer a promising therapeutic alternative to conventional antibiotics, which are becoming less effective due to rapidly emerging antibiotic resistance, there is a strong need to improve our understanding about the AMP mechanism of action. Recent literature suggests that AMPs often interact with the bacterial cell envelope at discrete foci. Here we review recent AMP literature, with an emphasis on focal interactions with bacteria, including (1 CAMP disruption mechanisms, (2 delocalization of membrane proteins and lipids by CAMPs, and (3 CAMP sensing systems and resistance mechanisms. We conclude with new approaches for studying the bacterial membrane, e.g., lipidomics, high resolution imaging and non-detergent-based membrane domain extraction.

  16. Biological effect of focal alpha radiation on the hamster lung

    International Nuclear Information System (INIS)

    Smith, D.M.; Anderson, E.C.; Prine, J.R.; Holland, L.M.; Richmond, C.R.

    1975-11-01

    Monodispersed 10-μm diameter ZrO 2 ceramic microspheres, containing varying amounts of 239 PuO 2 or 238 PuO 2 , were injected into the jugular vein of 100-day-old Syrian hamsters. These biologically inert microspheres lodged subsequently in pulmonary capillaries and remained static in position throughout the life span of the animals with no discernible inflammatory response. The numbers of microspheres injected ranged from 2000 to 10,000 and the specific activity from 0 to 59 pCi/sphere so that the lung burdens were 0 to 354 nCi/animal. At these numbers, each plutonium-laden microsphere served as an independent, focal source of alpha radiation. No consistent alteration of life spans post-exposure was seen in the experimental hamsters compared to controls. Pulmonary tissue responses were minimal with only 0.5 percent of the animals given Pu/ZrO 2 microspheres ultimately developing primary tumors of the lung. No unexpected gross or histologic lesion were found in other major body tissues

  17. A Micromachined Infrared Senor for an Infrared Focal Plane Array

    Directory of Open Access Journals (Sweden)

    Seong M. Cho

    2008-04-01

    Full Text Available A micromachined infrared sensor for an infrared focal plane array has been designed and fabricated. Amorphous silicon was used as a sensing material, and silicon nitride was used as a membrane material. To get a good absorption in infrared range, the sensor structure was designed as a l/4 cavity structure. A Ni-Cr film was selected as an electrode material and mixed etching scheme was applied in the patterning process of the Ni-Cr electrode. All the processes were made in 0.5 μm iMEMS fabricated in the Electronics and Telecommunication Research Institute (ETRI. The processed MEMS sensor had a small membrane deflection less than 0.15 μm. This small deflection can be attributed to the rigorous balancing of the stresses of individual layers. The efficiency of infrared absorption was more than 75% in the wavelength range of 8 ~ 14 μm. The processed infrared sensor showed high responsivity of ~230 kV/W at 1.0V bias and 2 Hz operation condition. The time constant of the sensor was 8.6 msec, which means that the sensor is suitable to be operated in 30 Hz frame rate.

  18. Performance overview of the Euclid infrared focal plane detector subsystems

    Science.gov (United States)

    Waczynski, A.; Barbier, R.; Cagiano, S.; Chen, J.; Cheung, S.; Cho, H.; Cillis, A.; Clémens, J.-C.; Dawson, O.; Delo, G.; Farris, M.; Feizi, A.; Foltz, R.; Hickey, M.; Holmes, W.; Hwang, T.; Israelsson, U.; Jhabvala, M.; Kahle, D.; Kan, Em.; Kan, Er.; Loose, M.; Lotkin, G.; Miko, L.; Nguyen, L.; Piquette, E.; Powers, T.; Pravdo, S.; Runkle, A.; Seiffert, M.; Strada, P.; Tucker, C.; Turck, K.; Wang, F.; Weber, C.; Williams, J.

    2016-07-01

    In support of the European space agency (ESA) Euclid mission, NASA is responsible for the evaluation of the H2RG mercury cadmium telluride (MCT) detectors and electronics assemblies fabricated by Teledyne imaging systems. The detector evaluation is performed in the detector characterization laboratory (DCL) at the NASA Goddard space flight center (GSFC) in close collaboration with engineers and scientists from the jet propulsion laboratory (JPL) and the Euclid project. The Euclid near infrared spectrometer and imaging photometer (NISP) will perform large area optical and spectroscopic sky surveys in the 0.9-2.02 μm infrared (IR) region. The NISP instrument will contain sixteen detector arrays each coupled to a Teledyne SIDECAR application specific integrated circuit (ASIC). The focal plane will operate at 100K and the SIDECAR ASIC will be in close proximity operating at a slightly higher temperature of 137K. This paper will describe the test configuration, performance tests and results of the latest engineering run, also known as pilot run 3 (PR3), consisting of four H2RG detectors operating simultaneously. Performance data will be presented on; noise, spectral quantum efficiency, dark current, persistence, pixel yield, pixel to pixel uniformity, linearity, inter pixel crosstalk, full well and dynamic range, power dissipation, thermal response and unit cell input sensitivity.

  19. Neuronal network disturbance after focal ischemia in rats

    International Nuclear Information System (INIS)

    Kataoka, K.; Hayakawa, T.; Yamada, K.; Mushiroi, T.; Kuroda, R.; Mogami, H.

    1989-01-01

    We studied functional disturbances following left middle cerebral artery occlusion in rats. Neuronal function was evaluated by [14C]2-deoxyglucose autoradiography 1 day after occlusion. We analyzed the mechanisms of change in glucose utilization outside the infarct using Fink-Heimer silver impregnation, axonal transport of wheat germ agglutinin-conjugated-horseradish peroxidase, and succinate dehydrogenase histochemistry. One day after occlusion, glucose utilization was remarkably reduced in the areas surrounding the infarct. There were many silver grains indicating degeneration of the synaptic terminals in the cortical areas surrounding the infarct and the ipsilateral cingulate cortex. Moreover, in the left thalamus where the left middle cerebral artery supplied no blood, glucose utilization significantly decreased compared with sham-operated rats. In the left thalamus, massive silver staining of degenerated synaptic terminals and decreases in succinate dehydrogenase activity were observed 4 and 5 days after occlusion. The absence of succinate dehydrogenase staining may reflect early changes in retrograde degeneration of thalamic neurons after ischemic injury of the thalamocortical pathway. Terminal degeneration even affected areas remote from the infarct: there were silver grains in the contralateral hemisphere transcallosally connected to the infarct and in the ipsilateral substantia nigra. Axonal transport study showed disruption of the corticospinal tract by subcortical ischemia; the transcallosal pathways in the cortex surrounding the infarct were preserved. The relation between neural function and the neuronal network in the area surrounding the focal cerebral infarct is discussed with regard to ischemic penumbra and diaschisis

  20. Focal plane mechanical design of the NISP/Euclid instrument

    Science.gov (United States)

    Bonnefoi, Anne; Bon, William; Niclas, Mathieu; Solheim, Bjarte G. B.; Torvanger, Oyvind; Schistad, Robert; Foulon, Benjamin; Garcia, José; Vives, Sébastien

    2016-07-01

    Currently in phase C, the Euclid mission selected by ESA in the Cosmic Vision program is dedicated to understand dark energy and dark matter. NISP (standing for Near Infrared Spectro-Photometer) is one of the two instruments of the mission. NISP will combine a photometer and a spectrometer working in the near-IR (0.9-2 microns). Its detection subsystem (called NI-DS) is based on a mosaic of 16 IR detectors cooled down to 90K which are supported by a molybdenum plate. The front-end readout electronics (working at 130K) are supported by another structure in Aluminum. The NI-DS is mounted on the rest of the instrument thanks to a panel in Silicon Carbide (SiC). Finally an optical baffle in Titanium will prevent the rogue light to reach the detectors. On top of the complexity due to the wide range of temperatures and the various materials imposed at the interfaces; the NI-DS has also to incorporate an internal adjustment capability of the position of the focal plane in tip/tilt and focus. This article will present current status of the development of the detection system of NISP.