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Sample records for richard binzel mit

  1. Richard III

    DEFF Research Database (Denmark)

    Lauridsen, Palle Schantz

    2017-01-01

    Kort analyse af Shakespeares Richard III med fokus på, hvordan denne skurk fremstilles, så tilskuere (og læsere) langt henad vejen kan føle sympati med ham. Med paralleller til Netflix-serien "House of Cards"......Kort analyse af Shakespeares Richard III med fokus på, hvordan denne skurk fremstilles, så tilskuere (og læsere) langt henad vejen kan føle sympati med ham. Med paralleller til Netflix-serien "House of Cards"...

  2. Professor Richard Feynman colloquium

    CERN Multimedia

    1965-01-01

    Richard P. Feynman received the Nobel Prize for physics in 1965. Following the ceremony in Stockholm, Feynman gave the colloquium "Development of the space-time view of quantum electrodynamics" at CERN on 17th December.

  3. Richard Halliburton's Bearded Tales

    Science.gov (United States)

    Morris, Charles E., III

    2009-01-01

    Fusing the concept of "the beard" with the genre of the tall tale to theorize bearded tales deepens our understanding of closet eloquence, or rhetorical repertories of sexual passing in U.S. history. An examination of adventurer-writer-lecturer Richard Halliburton's sexual provenance and bestselling travel tale, "The Royal Road to Romance" (1925),…

  4. Richards Bay effluent pipeline

    CSIR Research Space (South Africa)

    Lord, DA

    1986-07-01

    Full Text Available of major concern identified in the effluent are the large volume of byproduct calcium sulphate (phosphogypsum) which would smother marine life, high concentrations of fluoride highly toxic to marine life, heavy metals, chlorinated organic material... ........................ 9 THE RICHARDS BAY PIPELINE ........................................ 16 Environmental considerations ................................... 16 - Phosphogypsum disposal ................................... 16 - Effects of fluoride on locally occurring...

  5. Richard Wollheim über die Metapher in der Malerei

    OpenAIRE

    Heinrich, Richard

    1993-01-01

    Es handelt sich um den Text eines Vortrages, den ich Jänner 1993 im Rahmen einer Vortragsreihe am Institut für Kunstgeschichte der Universität Wien gehalten habe. Er ist bisher unpubliziert und nicht redigiert. Das worüber ich spreche ist ein Artikel von Richard Wollheim mit dem Titel "Die Metapher in der Malerei". Diesen Artikel habe ich herausgegeben, gemeinsam mit meinem Kollegen Helmuth Vetter, 1991 in dem Band "Bilder der Philosophie". Ursprünglich handelt es sich um einen Vortrag, d...

  6. Richard von Volkmann

    Science.gov (United States)

    Willy, Christian; Schneider, Peter; Engelhardt, Michael; Hargens, Alan R.

    2008-01-01

    Richard von Volkmann (1830–1889), one of the most important surgeons of the 19th century, is regarded as one of the fathers of orthopaedic surgery. He was a contemporary of Langenbeck, Esmarch, Lister, Billroth, Kocher, and Trendelenburg. He was head of the Department of Surgery at the University of Halle, Germany (1867–1889). His popularity attracted doctors and patients from all over the world. He was the lead physician for the German military during two wars. From this experience, he compared the mortality of civilian and war injuries and investigated the general poor hygienic conditions in civilian hospitals. This led him to introduce the “antiseptic technique” to Germany that was developed by Lister. His powers of observation and creativity led him to findings and achievements that to this day bear his name: Volkmann’s contracture and the Hueter-Volkmann law. Additionally, he was a gifted writer; he published not only scientific literature but also books of children’s fairy tales and poems under the pen name of Richard Leander, assuring him a permanent place in the world of literature as well as orthopaedics. PMID:18196438

  7. Mit kokkeri

    DEFF Research Database (Denmark)

    Ejlersen, Søren; Lorang, Louisa

    MIT kokkeri er resultatet af et samarbejde mellem Komiteen for Sundhedsoplysning, Institut for Uddannelse og Pædagogik/Aarhus Universitet og Haver til Maver. Projektet støttes af Nordea-fonden. Bag kogebogens mange opskrifter står en række erfarne madeksperter bestående af Søren Ejlersen, Louisa...

  8. Richard Lavenham on Future Contingents

    DEFF Research Database (Denmark)

    Øhrstrøm, Peter

    1983-01-01

    Richard Lavenham on Future Contingents’, Cahiers de l’Institut du Moyen-âge Grec et Latin, 44 (1983), p.180-186.......‘Richard Lavenham on Future Contingents’, Cahiers de l’Institut du Moyen-âge Grec et Latin, 44 (1983), p.180-186....

  9. Richard H. Thaler: Wirtschaftsnobelpreisträger 2017

    OpenAIRE

    Bruttel, Lisa Verena; Stolley, Florian

    2017-01-01

    Der diesjährige Nobelpreisträger Richard H. Thaler ist einer breiteren Öffentlichkeit vor allem durch sein mit Cass R. Sunstein gemeinsam verfasstes Buch zum Nudging bekannt geworden. Tatsächlich hat er in den vergangenen 40 Jahren die Entwicklung der Verhaltensökonomie entscheidend mitgeprägt und vorangebracht. Thaler hat die Annahmen hinter dem Modell des Homo oeconomicus untersucht und die Abweichungen menschlichen Verhaltens von den Rationalitätsannahmen auf zwei wesentliche Ursachen zurü...

  10. In Conversation with Paul Richards

    Science.gov (United States)

    Holman, Andrew

    2013-01-01

    Paul Richards is one of those individuals who make a difference and is as far from institutional as one can be. The author met up with him at the Learning Disability Today conference in London to talk more about his work and life. Paul coordinates the service user involvement across Southdown Housing Association, based in Sussex.

  11. Richard Peters and Valuing Authenticity

    Science.gov (United States)

    Degenhardt, M. A. B.

    2009-01-01

    Richard Peters has been praised for the authenticity of his philosophy, and inquiry into aspects of the development of his philosophy reveals a profound authenticity. Yet authenticity is something he seems not to favour. The apparent paradox is resolved by observing historical changes in the understanding of authenticity as an important value.…

  12. Obituary: Dr. Richard Roland Baker

    Directory of Open Access Journals (Sweden)

    Thornton R

    2014-12-01

    Full Text Available Richard Baker died at Easter 2007 after a very short illness. It is sad that he died so soon after his retirement from the British American Tobacco Company at the end of 2005, and just as he was beginning to enjoy his new life, even though tobacco science still had a part to play.

  13. Richard Mattessich: vida y obra

    OpenAIRE

    Daniel Carrasco Díaz

    2006-01-01

    El texto que se ofrece a continuación constituye el discurso pronunciado por el profesor Daniel Carrasco Díaz, catedrático de Economía Financiera y Contabilidad como padrino del homenajeado, en el solemne acto de investidura del Prof. Dr. Richard Mattessich, profesor emérito de la Sauder School of Commerce, de la University of British Columbia, Vancouver (Canadá), como Doctor honoris causa por la Universidad de Málaga, celebrado el 18 de mayo de 2006.

  14. J. Richard Hackman (1940-2013)

    OpenAIRE

    Wageman, Ruth; Amabile, Teresa M.

    2013-01-01

    When J. Richard Hackman died in Cambridge, Massachusetts, on January 8, 2013, psychology lost a giant. Six and a half feet tall, with an outsize personality to match, Richard was the leading scholar in two distinct areas: work design and team effectiveness. In both domains, his work is foundational. Throughout his career, Richard applied rigorous methods to problems of great social importance, tirelessly championing multi-level analyses of problems that matter. His impact on our field has bee...

  15. Richard's back: death, scoliosis and myth making.

    Science.gov (United States)

    Lund, Mary Ann

    2015-12-01

    The body of a mediaeval monarch was always under scrutiny, and Richard III's was no exception. In death, however, his body became subject to new forms of examination and interpretation: stripped naked after the battle of Bosworth, his corpse was carried to Leicester and exhibited before being buried. In 2012, it was rediscovered. The revelation that Richard suffered from scoliosis prompts this article to re-evaluate the historical sources about Richard's physique and his posthumous reputation. This article argues that Richard's death and his myth as 'crookback' are inextricably linked and traces attitudes to spinal curvature in the early modern period. It also considers how Shakespeare represented Richard as deformed, and aspects of performance history which suggest physical vulnerability. It then considers Richard's scoliosis from the perspective of medical history, reviewing classical accounts of scoliosis and arguing that Richard was probably treated with a mixture of axial traction and pressure. It demonstrates from the evidence of Richard's medical household that he was well placed to receive hands-on therapies and considers in particular the role of his physician and surgeon, William Hobbes. Finally, it shows how the case of Richard III demonstrates the close relationship between politics and medicine in the period and the contorted process of historical myth making. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  16. Marketing mit Youtube

    OpenAIRE

    Nufer, Gerd; Kaps, Anne

    2017-01-01

    Die Video-Plattform Youtube ist eine der meistbesuchten Webseiten weltweit. Youtube-Stars erreichen mit ihren Videos große Zuschauergruppen und können als Multiplikatoren für Werbebotschaften dienen. Sie sind oftmals Meinungsführer, denen hohes Vertrauen entgegengebracht wird, weshalb sie sich sehr gut für Influencer-Marketing eignen. Marketing mit Youtube ermöglicht eine offene, mehrwegige, schnelle und kostengünstige Kommunikation mit Kunden, insbesondere jüngeren. Unternehmen können sich d...

  17. MITS machine operations

    International Nuclear Information System (INIS)

    Flinchem, J.

    1980-01-01

    This document contains procedures which apply to operations performed on individual P-1c machines in the Machine Interface Test System (MITS) at AiResearch Manufacturing Company's Torrance, California Facility

  18. Kommunikation mit Mitarbeitern

    Science.gov (United States)

    Spychala, Anne; Fleischmann, Jürgen

    Kommunikation ist der Austausch von Nachrichten und Informationen zwischen Mitarbeitern eines Unternehmens (O'Hair et al. 1997). Dieser Austausch kann persönlich, aber z.B. auch per Telefon, E-Mail oder durch Computersysteme erfolgen. In diesem Kapitel betrachten wir die persönliche Kommunikation zwischen Vorgesetzten und Mitarbeitern. Zur persönlichen Kommunikation mit Mitarbeitern zählen sowohl formelle Gespräche mit Mitarbeitern als auch eher informelle Gespräche zwischen Tür und Angel. Die Gespräche können dabei mit einzelnen Mitarbeitern (z.B. jährliches Mitarbeitergespräch) oder mit Gruppen von Mitarbeitern (z.B. regelmäßige Projekt- oder Teambesprechungen) stattfinden.

  19. Richard Nixon, 1972-2016 Obituary

    OpenAIRE

    Tom, Brian Dermot; Thompson, Simon Gregory; Duffy, SW; Sweeting, Michael John; Ohlssen, DI

    2017-01-01

    After a year-long journey with cancer, Dr Richard Nixon died on August 26th, 2016, aged only 43 years. He leaves behind his wife of 5 years, Valda, and their 1-year-old baby daughter, Kyra. Richard, a Yorkshireman, was born on September 8th, 1972. He attended Ilkley Grammar School, studied mathematics at Durham University (1991–1994) and was awarded the Diploma in Mathematical Statistics from the University of Cambridge in 1995. Richard then took a career break for a couple of years to...

  20. Theodore William Richards and the Periodic Table

    Science.gov (United States)

    Conant, James B.

    1970-01-01

    Discusses the contribution of Theodore Richards to the accurate determination of atomic weights of copper and other elements; his major contribution was to the building of the definitive periodic table of the elements. (BR)

  1. Richards Barrier LA Reference Design Feature Evaluation

    International Nuclear Information System (INIS)

    N.E. Kramer

    1999-01-01

    The Richards Barrier is one of the design features of the repository to be considered for the License Application (LA), Richards was a soil scientist who first described the diversion of moisture between two materials with different hydrologic properties. In this report, a Richards Barrier is a special type of backfill with a fine-grained material (such as sand) overlaying a coarse-grained material (such as gravel). Water that enters an emplacement drift will first encounter the fine-grained material and be transported around the coarse-grained material covering the waste package, thus protecting the waste package from contact with most of the groundwater. The objective of this report is to discuss the benefits and liabilities to the repository by the inclusion of a Richards Barrier type backfill in emplacement drifts. The Richards Barrier can act as a barrier to water flow, can reduce the waste package material dissolution rate, limit mobilization of the radionuclides, and can provide structural protection for the waste package. The scope of this report is to: (1) Analyze the behavior of barrier materials following the intrusion of groundwater for influxes of 1 to 300 mm per year. The report will demonstrate diversion of groundwater intrusions into the barrier over an extended time period when seismic activity and consolidation may cause the potential for liquefaction and settlement of the Richards Barrier. (2) Review the thermal effects of the Richards Barrier on material behavior. (3) Analyze the effect of rockfall on the performance of the Richards Barrier and the depth of the barrier required to protect waste packages under the barrier. (4) Review radiological and heating conditions on placement of multiple layers of the barrier. Subsurface Nuclear Safety personnel will perform calculations to determine the radiation reduction-time relationship and shielding capacity of the barrier. (5) Evaluate the effects of ventilation on cooling of emplacement drifts and

  2. Mit anderen Augen

    DEFF Research Database (Denmark)

    Ydesen, Christian; Høberg, Per

    2010-01-01

    The article 'Mit anderen Augen' focuses on the debate about the state-church relationship in the German Democratic Republic (GDR). Starting from the immediate assumption that a protestant church and a socialist, Marxist-Leninist state were irreconcilable in the construction of a new society...

  3. In conversation with: Professor Richard James

    Directory of Open Access Journals (Sweden)

    John Clarke

    2014-03-01

    Full Text Available In 2011, Richard James wrote in the Foreword to Nelson, Clarke, Kift, and Creagh’s (2012 monograph on Australasian literature on the First Year Experience that:The trend towards universal participation will usher in dramatic changes in the character of the first year in higher education. … (p. iiiIn an interview at the University of Melbourne, Australia in July 2013 between Richard James and John Clarke, Co-editor of the International Journal of the First Year in Higher Education, these and related issues were explored.  The interview picks up where the Foreword left off:  focussing on universal participation.

  4. Quantum Man: Richard Feynman's Life in Science

    CERN Document Server

    CERN. Geneva

    2011-01-01

    It took a man who was willing to break all the rules to tame a theory that breaks all the rules. This talk will be based on my new book Quantum Man: Richard Feynman's life in science. I will try and present a scientific overview of the contributions of Richard Feynman, as seen through the arc of his fascinating life. From Quantum Mechanics to Antiparticles, from Rio de Janeiro to Los Alamos, a whirlwind tour will provide insights into the character, life and accomplishments of one of the 20th centuries most important scientists, and provide an object lesson in scientific integrity.

  5. Obituary: Richard Joseph Elston, 1960-2004

    Science.gov (United States)

    Jannuzi, Buell Tomasson; Bechtold, Jill

    2004-12-01

    Richard Joseph Elston, known for his development of innovative astronomical instrumentation, died on 26 January 2004 in Gainesville, Florida, after a four-year battle with Hodgkin's lymphoma. A professor of astronomy at the University of Florida, Richard had an unusually broad range of interests and skills, and a willingness to share his passion for astronomy with others, which made him a highly valued member of the astronomical community. Born 1 July 1960, in Albuquerque, New Mexico, Richard was the son of a geologist father and journalist mother. His childhood interest in astronomy and instrumentation matured as he majored in physics and astronomy at the University of New Mexico (BS, 1983) under the mentorship of Michael Zeilik. Richard pursued his PhD in astronomy at the University of Arizona and earned his degree in 1988. He pioneered the use of IR arrays for deep imaging surveys of the sky to study galaxy formation, and completed his thesis Search for Rapidly Forming Galaxies at High Redshift under the direction of George Rieke. Richard's graduate work included the first detection of galaxies at intermediate redshifts with evolved populations too red to have been identifiable from optical imaging surveys alone. In the Astrophysical Journal Letters in 1988, he, George Rieke, and Marcia Rieke reported the discovery of this new class of galaxies, now known as EROs (Extremely Red Objects), important as the possible progenitors of present day elliptical galaxies. Following post-doctoral positions at Kitt Peak National Observatory from 1988 to 1991 and at the Observatories of the Carnegie Institution of Washington from 1991 to 1992, Richard joined the scientific staff of Cerro Tololo Inter-American Observatory in Chile, part of the NSF's National Optical Astronomy Observatory. By 1994, he had become head of CTIO's IR instrumentation program and was leading the development of new instruments for the US astronomical community. In 1996, Richard married astronomer

  6. Richard W. Ziolkowski Receives Honorary Doctorate

    DEFF Research Database (Denmark)

    Breinbjerg, Olav

    2012-01-01

    At the annual Commemoration of the Technical University of Denmark (DTU) on April 27, 2012, Prof. Richard W. Ziolkowski, University of Arizona (UoA), received DTU's highest academic degree, the Honorary Doctor degree: Doctor Technices Honoris Causa (Figure 1). Prof. Ziolkowski has been a close...

  7. Potshemu medved rõtshit / Richard Pipes

    Index Scriptorium Estoniae

    Pipes, Richard

    2006-01-01

    Harvardi ülikooli ajalooprofessor Richard Pipes arutleb, miks Venemaa viimase aja käitumises väljendub soovimatus koostööks, sageli ka vaenulikkus. Venemaa võimetus rahvusvahelises kontekstis oma kohta leida, selle ajaloolised juured

  8. Richard A. Werners forskning i pengeskabelse

    DEFF Research Database (Denmark)

    2016-01-01

    Hvilken rolle spiller penge i samfundsøkonomien og hvilken rolle burde penge spille i den økonomiske videnskab? Det forsker Richard Werner i. Han er professor i økonomi ved Southampton University i England, og her præsenteres fire dele af hans forskning i penge: (1) Hvad foregår der egentlig i en...

  9. Recensie "The Great Reset" : Richard Florida

    NARCIS (Netherlands)

    Roy van Dalm

    2010-01-01

    Like the Great Depression and the Long Depression before it, experts have viewed prolonged economic downturns as crises. In The Great Reset , bestselling author Richard Florida argues that we should instead see the recent recession as an opportunity to create entirely new ways of working and living

  10. Richard Florida : loovsektor on majanduskasvu mootor / Richard Florida ; interv. Argo Ideon

    Index Scriptorium Estoniae

    Florida, Richard

    2008-01-01

    USA majandus- ja ühiskonnateadlane Richard Florida loovklassi teooriast, selle osast majanduskasvu tagamisel, seosest ühiskonna tolerantsuse ja ühiskonna majandusliku edukuse vahel, sotsiaalse sidususe takistavast rollist loovuse motiveerimisel

  11. Method of lines solution of Richards` equation

    Energy Technology Data Exchange (ETDEWEB)

    Kelley, C.T.; Miller, C.T.; Tocci, M.D.

    1996-12-31

    We consider the method of lines solution of Richard`s equation, which models flow through porous media, as an example of a situation in which the method can give incorrect results because of premature termination of the nonlinear corrector iteration. This premature termination arises when the solution has a sharp moving front and the Jacobian is ill-conditioned. While this problem can be solved by tightening the tolerances provided to the ODE or DAE solver used for the temporal integration, it is more efficient to modify the termination criteria of the nonlinear solver and/or recompute the Jacobian more frequently. In this paper we continue previous work on this topic by analyzing the modifications in more detail and giving a strategy on how the modifications can be turned on and off in response to changes in the character of the solution.

  12. Richard Weaver's Untraditional Case for Federalism

    OpenAIRE

    Jeremy David Bailey

    2004-01-01

    Although Richard M. Weaver's political writings do not offer a systematic examination of federalism, they include a defense of federalist arrangements. Because Weaver's federalism is central to his conservatism, and because his argument for federalism differs from more common conservative defenses of federalism offered in the twentieth century, his writings allow students of federalism to examine possible connections between federalism and conservative political thought. Copyright 2004, Oxfor...

  13. Richard Wollheim 1923-2003 / Marek Volt

    Index Scriptorium Estoniae

    Volt, Marek

    2004-01-01

    Järelehüüe anglo-ameerika filosoofile Richard Wollheimile (5. V 1923-4. XI 2003), kes huvitus maalist ja psühhoanalüüsist ning kuulub XX sajandi analüütilist kunstifilosoofiat enim kujundanud filosoofide hulka. Tema peamised tööd: "Art and Its Objects" (1968), "Painting As an Art" (1987), "On Painting and the Self" (1992). Ilmunud ka raamatus: Volt, Marek. Esteetikast. Tallinn : Sirp, 2006

  14. Illustrated & Dissected: Professor Richard Sawdon Smith.

    Science.gov (United States)

    2015-06-01

    This Alternative Gallery feature introduces the photographic artist Professor Richard Sawdon Smith. Professor Sawdon Smith's work stems around a fascination with representations of anatomy that have been fuelled by his experience as a hospital patient. The work has allowed him to explore ideas through the use of medical illustrations which include early anatomical drawings, personal medical photography and facial modelling. The work highlights how such imagery can be used in the context of a patient seeking understanding and acceptance of ill health and disease using the body as a canvas on which to translate the experience.

  15. Richard Bright and his neurological studies.

    Science.gov (United States)

    Pearce, J M S

    2009-01-01

    Richard Bright was one of the famous triumvirate of Guy's Hospital physicians in the Victorian era. Remembered for his account of glomerulonephritis (Bright's disease) he also made many important and original contributions to medicine and neurology. These included his work on cortical epileptogenesis, descriptions of simple partial (Jacksonian) seizures, infantile convulsions, and a variety of nervous diseases. Most notable were his reports of neurological studies including papers on traumatic tetanus, syringomyelia, arteries of the brain, contractures of spinal origin, tumours of the base of the brain, and narcolepsy. His career and these contributions are outlined. Copyright 2009 S. Karger AG, Basel.

  16. Richard Feynman a life in science

    CERN Document Server

    Gribbin, John

    1998-01-01

    This text is a portrayal of one of the greatest scientists of the late 20th-century, which also provides a picture of the significant physics of the period. It combines personal anecdotes, writings and recollections with narrative. Richard Feynman's career included: war-time work on the atomic bomb at Los Alamos; a theory of quantum mechanics for which he won the Nobel prize; and major contributions to the sciences of gravity, nuclear physics and particle theory. In 1986, he was able to show that the Challenger disaster was due to the effect of cold on the booster rocket rubber sealings.

  17. Richard Feynman Quarks, Bombs, and Bongos

    CERN Document Server

    Henderson, Harry

    2010-01-01

    Described by his peers as the "finest physicist of his generation," Richard Feynman defied scientist stereotypes. This brash New York-born American physicist startled the more conservative giants of European physics with his endless ability to improvise. Indeed, later in life, Feynman became an accomplished bongo player. Feynman's legacy to physics was his ability to simplify complex equations and clarify fundamental principles through the use of graphs. He developed the theory of quantum electrodynamics, which illustrates the behavior of electrically charged particles, such as elect

  18. An appreciation of Richard Threlkeld Cox

    Science.gov (United States)

    Tribus, Myron

    2002-05-01

    Richard T. Cox's contributions to the foundations of probability theory and inductive logic are not generally appreciated or understood. This paper reviews his life and accomplishments, especially those in his book The Algebra of Probable Inference and his final publication Inference and Inquiry which, in this author's opinion, has the potential to influence in a significant way the design and analysis of self organizing systems which learn from experience. A simple application to the simulation of a neuron is presented as an example of the power of Cox's contribution.

  19. Richard von Volkmann: surgeon and Renaissance man.

    Science.gov (United States)

    Willy, Christian; Schneider, Peter; Engelhardt, Michael; Hargens, Alan R; Mubarak, Scott J

    2008-02-01

    Richard von Volkmann (1830-1889), one of the most important surgeons of the 19(th) century, is regarded as one of the fathers of orthopaedic surgery. He was a contemporary of Langenbeck, Esmarch, Lister, Billroth, Kocher, and Trendelenburg. He was head of the Department of Surgery at the University of Halle, Germany (1867-1889). His popularity attracted doctors and patients from all over the world. He was the lead physician for the German military during two wars. From this experience, he compared the mortality of civilian and war injuries and investigated the general poor hygienic conditions in civilian hospitals. This led him to introduce the "antiseptic technique" to Germany that was developed by Lister. His powers of observation and creativity led him to findings and achievements that to this day bear his name: Volkmann's contracture and the Hueter-Volkmann law. Additionally, he was a gifted writer; he published not only scientific literature but also books of children's fairy tales and poems under the pen name of Richard Leander, assuring him a permanent place in the world of literature as well as orthopaedics.

  20. Seeing Scale: Richard Dunn’s Structuralism

    Directory of Open Access Journals (Sweden)

    Keith Broadfoot

    2012-11-01

    Full Text Available Writing on the occasion of a retrospective of Richard Dunn’s work, Terence Maloon argued that ‘structuralism had an important bearing on virtually all of Richard Dunn’s mature works’, with ‘his modular, “crossed” formats’ being the most obvious manifestation of this. In this article I wish to reconsider this relation, withdrawing from a broad consideration of the framework of structuralism to focus on some of the quite particular ideas that Lacan proposed in response to structuralism. Beginning from a pivotal painting in the 1960s that developed out of Dunn’s experience of viewing the work of Barnett Newman, I wish to suggest a relation between the ongoing exploration of the thematic of scale in Dunn’s work and the idea of the symbolic that Lacan derives from structuralist thought. This relation, I argue, opens up a different way of understanding the art historical transition from Minimalism to Conceptual art.

  1. Die Last mit der Lust

    Directory of Open Access Journals (Sweden)

    Lutz Sauerteig

    2004-03-01

    Full Text Available Robert Jütte legt mit Lust ohne Last eine umfassende, allgemeinverständliche und spannend zu lesende Geschichte der Empfängnisverhütung von der Antike bis in die unmittelbare Gegenwart vor.

  2. Spillerum og mit eget rum

    DEFF Research Database (Denmark)

    2014-01-01

    Undervisningsmaterialet Spillerum udviklet som APP til Ipad med interaktive muligheder. Spillerum som APP - et interaktivt undervisningsmateriale, hvor man ud over at bruge det originale materiale Spillerum elektronisk kan skabe sit eget billedbaserede rum "Mit eget rum" som udgangspunkt for dialog....

  3. Kleben von Kunststoff mit Metall

    CERN Document Server

    Brockmann, W; Käufer, H

    1989-01-01

    Das Buch behandelt das Kleben von Kunststoffen mit Metallen in einer fur den Praktiker verstandlichen und umsetzbaren Form. Es leitet zu Klebeverfahren an, die optimale Ergebnisse hinsichtlich Qualitat, Dauerhaftigkeit und Wirtschaftlichkeit liefern.

  4. MIT-CSR XIS Project

    Science.gov (United States)

    1998-01-01

    This report outlines the proposers' progress toward MIT's contribution to the X-Ray Imaging Spectrometer (XIS) experiment on the Japanese ASTRO-E mission. The report discusses electrical system design, mechanical system design, and ground support equipment.

  5. Conoscenza e etica in Richard Rorty

    Directory of Open Access Journals (Sweden)

    Emilia Romano

    2011-12-01

    Full Text Available The era in which we live, characterized by multiculturalism and complexity, it is a time when it is clear the difficulty of man to orient and to choose their own way. It’s the time of the fall of every certainty, is the era of “post”, after the tradition, after metaphysics, after the truth, and that requires more effort than any other constant reflection. The neopragmatismo seems to be an effective investigative tool for conducting this reflection and a vantage point to carry on a conversation around the issues of education. In particular, the author intended to refer to the work of Richard Rorty, the author who more than others reflected on the encounter between two important pragmatist tradition: that of classical pragmatism and the “continental” or responsible for the development of a new European concept of truth, understood as a critical and interpretative.

  6. El vocabulario sechurano de Richard Spruce

    Directory of Open Access Journals (Sweden)

    Matthias Urban

    2015-12-01

    Full Text Available This paper makes accesible a new transcription of Richard Spruce’s vocabulary of the Sechura language. Collected in the mid-19th century by the British botanist, it constitutes one of only two sources of data for this language of northernmost Peru. A comparison of the original with previously published versions shows serious errors in transcription, in particular in those of Otto von Buchwald and Jacinto Jijón y Camaaño. The article also discusses the probable circumstances of data collection and the publication history of the hitherto known version, and concludes with some first observations on the significance of Spruce’s wordlist for elucidating the linguistic history of the region, in particular with regard to the question of the linguistic situation at Olmos.

  7. Has Richard Rorty a moral philosophy?

    Directory of Open Access Journals (Sweden)

    Mohammad Asghari

    2015-06-01

    Full Text Available I try to show that Richard Rorty, although is not a moral philosopher like Kant, nerveless, has moral philosophy that must be taken seriously. Rorty was not engaged with moral philosophy in the systematic manner common among leading modern and contemporary moral philosophers. This paper has two parts: first part, in brief, is concerned with principles of his philosophy such as anti-essentialism, Darwinism, Freudism, and historicism. Second part which be long and detailed, considers many moral themes in Rorty's thought such as critique of Kantian morality, solidarity, moral progress, cruelty and concept of other, etc. Subsequently, I will try to answer the research question of the article namely, has Rorty a moral philosophy?

  8. 77 FR 21555 - Manning, Richard W.; Notice of Filing

    Science.gov (United States)

    2012-04-10

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ID-6835-001] Manning, Richard W.; Notice of Filing Take notice that on April 2, 2012, Richard W. Manning submitted for filing... not serve to make protestants parties to the proceeding. Any person wishing to become a party must...

  9. Richard Avedon ja Annie Leibovitz laulsid kaanonit / Marika Alver

    Index Scriptorium Estoniae

    Alver, Marika

    2008-01-01

    Richard Avedoni (1923-2004) retrospektiivnäitusest (fotod aastatest 1946-2004) kuraator Helle Crenzien (Lousiana Kaasaegse Kunsti muuseum Taanis), millega kaasnes ka Helen Whitney film "Richard Avedon : darkness and light" ja Annie Leibovitzi (1949) suurprojektist "A photographer's life 1990-2005" Pariisis

  10. Obituary: Richard D. Schwartz (1941-2011)

    Science.gov (United States)

    Wilking, Bruce

    2011-12-01

    Richard D. Schwartz, Professor Emeritus of Astronomy, died at his home in Sequim, WA, after a nearly 3 year battle against pancreatic cancer. Richard was born in Pretty Prairie, Kansas. He was active in sports and band and graduated in 1959. After completing a BS at Kansas State, and a Master's degree in Divinity at Union Seminary in NY, he further studied astrophysics, receiving his doctorate from University of Washington in 1973. When Dick arrived at the University of Missouri-St. Louis in 1975, he was the only astronomer in the Department of Physics. He built the astronomy program and initiated the B.S. in physics with an astrophysics option that the majority of physics majors choose. Dick was a wonderful teacher and provided outstanding leadership to the campus. He designed and provided oversight on the construction of the campus observatory that was completed in 1981. Since that time the observatory has served as both a teaching and research facility. It is also used for monthly public open houses that draw hundreds of people annually to the campus to view the moon, stars, and planets. Upon his retirement in 2003, the Board of Curators approved naming the campus observatory the "Richard D. Schwartz Observatory" in honor of his distinctive service to the University of Missouri-St. Louis. Just as important as Dick's service to promote public interest in astronomy was his effort to make the campus observatory a research facility. Dick equipped and maintained the observatory with state-of-art detectors that allowed students to get their first taste of scientific research. From 1991-2003, he managed the campus program for the NASA/Missouri Space Grant Consortium and mentored over 30 research students in projects at the observatory. Some of the results have been published in astronomical journals. Many of those students went on to graduate schools and several have achieved tenure and distinction at major universities. In addition to Dick's service to the University

  11. Richard Murphy: a life in writing

    Directory of Open Access Journals (Sweden)

    E. Meihuizen

    2006-07-01

    Full Text Available The Irish poet Richard Murphy published his autobiography “The kick: a life among writers” in 2003. From a slightly different perspective the subtitle of this work could be rewritten as “A life in writing” since it is an account of the agencies that moulded a life devoted to creative writing which forms the book’s essential impetus. The memoir is based on notebooks which Murphy kept throughout his life “to hold the scraps of verse, elusive images, dreams, desires and revelations” to be developed into poetry. Apart from contextualising his poetry by registering the relationships, circumstances and landscapes from which it germinated, Murphy also tells of the creative process itself and the personal poetics underlying this process. This article explores what is regarded as the central determining feature of Murphy’s identity as poet, namely the relationship between the creative self and a particular place, where the concept of “place” is seen as a cultural palimpsest which represents not only physical qualities, but also the shaping and development of the landscape through time according to a certain way of life.

  12. Richard Murphy: Autobiography and the Connemara landscape

    Directory of Open Access Journals (Sweden)

    Elsa Meihuizen

    2015-08-01

    Full Text Available It could be argued that an important feature of Richard Murphy’s work, and of his identity as a poet is the relationship between the creative self and a particular place, where ‘place’ should be understood as referring not just to physical qualities of the natural environment, but in a broader sense to denote an environment in which everything is interrelated and connected, and in which there is no sharp division between the natural and the human. The landscape providing inspiration for Murphy’s poetic imagination is the landscapes and seascapes of Connemara in north-west Ireland. In 1959 he settled in this environment which was to be his base for the next 20 years and from this period and this location emanated the bulk of his poetic oeuvre. For Murphy committing to a life of writing poetry necessarily means being in the Connemara landscape. Returning to this environment in adulthood represents a quest for recovering childhood feelings, of belonging and love, as connected to particular places. Murphy’s Connemara poems could be read as an account of this process of re-placement, as a type of autobiographical text in which the artist creates a ‘double portrait’: in writing about the landscape he also writes about himself, creating a place-portrait which is, at the same time, a self-portrait.

  13. Richard Swedberg, The Art of Social Theory

    DEFF Research Database (Denmark)

    Carleheden, Mikael

    2015-01-01

    to systematic consideration. Swedberg attributes this strange absence to what he sees as the miserable state of contemporary social theory. We must, he claims, avoid two misconceptions: ‘empiricism’ and ‘abstract theory’. In the first case, theory is reduced to the task of summarizing the outcome of empirical......It is a rare event when a new general field of research opens up within sociology. However, with this book, Richard Swedberg intends to do just that. It is not just another book on social theory. It is a book on ‘theorizing’. And that makes all the difference. Swedberg has chosen the term ‘art......’, but also ‘craft’, to emphasize the practical side of doing theory. This topic has been strangely absent, not just in sociology but in the social sciences in general. In order to see this absence, we should ask ourselves how education in sociology is conventionally organized. The answer is by a taken...

  14. Kuues väljasuremine / Richard Leakey, Roger Lewin

    Index Scriptorium Estoniae

    Leakey, Richard

    2002-01-01

    Inimtegevuse hävitavast toimest looduslikule mitmekesisusele, mis tingib loodusliku energiatootmise järsu kahanemise, millest omakorda sõltub inimese enda ellujäämine. Lühidalt Richard Leakey'st

  15. Swearing Used in Richard Wright’s Black Boy

    OpenAIRE

    Giyatmi Giyatmi; Ratih WIjayava; Nunun Tri Widarwati

    2017-01-01

    This research aims at finding the types of swearing expressions and linguistic forms of English swearing used in Richard Wright's Black Boy. This is a descriptive qualitative research since it describes the phenomena of swearing used in the novel. The data of the research are all the conversations or sentences used swearing in the novel written by Richard Wright namely Black Boy as the main data source. The method of collecting data in this research is observation and teknik lanjut catat. Aft...

  16. MITS instrumentation error analysis report

    International Nuclear Information System (INIS)

    Nelson, D.W.; Hillon, D.D.

    1980-01-01

    The MITS (Machine Interface Test System) installation consists of three types of process monitoring and control instrumentation: flow, pressure, and temperature. An effort has been made to assess the various instruments used and assign a value to the accuracy that can be expected. Efforts were also made to analyze the calibration and installation procedures to be used and determine how these might effect the system accuracy

  17. MIT miniaturized disk bend test

    International Nuclear Information System (INIS)

    Harling, O.K.; Lee, M.; Sohn, D.S.; Kohse, G.; Lau, C.W.

    1983-01-01

    A miniaturized disk bend test (MDBT) using transmission electron microscopy specimens for the determination of various mechanical properties is being developed at MIT. Recent progress in obtaining strengths and ductilities of highly irradiated metal alloys is reviewed. Other mechanical properties can also be obtained using the MDBT approach. Progress in fatigue testing and in determination of the ductile-to-brittle transition temperature is reviewed briefly. 11 figures

  18. Obituary: Richard B. Dunn, 1927-2005

    Science.gov (United States)

    Keil, Stephen L.; Dooling, David

    2007-12-01

    Dr. Richard B. Dunn, astronomer emeritus at the National Solar Observatory, died of a heart attack on September 29, 2005. He was recognized as one of the foremost experimental solar physicists. His innovative designs for telescopes and instruments led to many important discoveries in solar physics. Born in Baltimore, Maryland, in 1927 and raised in Minneapolis, Minnesota, Dick's parents were Dr. Halbert L. Dunn and Katherine Brandner. Halbert (MD, Ph.D., F.A.P.H.A.) was an physician who became Chief of the National Office of Vital Statistics, Public Health Service. He published a paper "High Level Wellness for Man and Society" that became the founding paper of the field of wellness health care. After their divorce in 1942, Katherine moved to New York and became a social worker. Dick had two older brothers who died before him, Halbert (born in 1921, who became a civil engineer) and Robert (born in 1924, who became an architect). Dick earned a BS in mechanical engineering and an MS in astronomy at the University of Minnesota. At the end of World War II he served in the United States Army in Japan. For his master's degree, Dick undertook the design and construction of a Lyot-type birefringent filter for observations of solar prominences. This early work led to his acceptance at Harvard, where Professor Donald Menzel encouraged him to continue his work with the 15-inch Cambridge telescope. In 1951 he conducted part of his doctoral thesis work at the fledgling Sacramento Peak Observatory in southern New Mexico. The observatory director, Dr. John Evans, was impressed with Dick's outstanding instrumental talents and invited him to join as one of the first scientific staff members. During his first few years at Sac Peak, Dick developed two more birefringent filter systems including one with an integrated coronagraph. With this system, he produced the best prominence and spicule observations ever obtained. Dick's career was dedicated to obtaining solar observations of the

  19. MIT pebble bed reactor project

    Energy Technology Data Exchange (ETDEWEB)

    Kadak, Andrew C. [Massachusetts Institute of Technology, Cambridge (United States)

    2007-03-15

    The conceptual design of the MIT modular pebble bed reactor is described. This reactor plant is a 250 Mwth, 120 Mwe indirect cycle plant that is designed to be deployed in the near term using demonstrated helium system components. The primary system is a conventional pebble bed reactor with a dynamic central column with an outlet temperature of 900 C providing helium to an intermediate helium to helium heat exchanger (IHX). The outlet of the IHX is input to a three shaft horizontal Brayton Cycle power conversion system. The design constraint used in sizing the plant is based on a factory modularity principle which allows the plant to be assembled 'Lego' style instead of constructed piece by piece. This principle employs space frames which contain the power conversion system that permits the Lego-like modules to be shipped by truck or train to sites. This paper also describes the research that has been conducted at MIT since 1998 on fuel modeling, silver leakage from coated fuel particles, dynamic simulation, MCNP reactor physics modeling and air ingress analysis.

  20. MIT pebble bed reactor project

    International Nuclear Information System (INIS)

    Kadak, Andrew C.

    2007-01-01

    The conceptual design of the MIT modular pebble bed reactor is described. This reactor plant is a 250 Mwth, 120 Mwe indirect cycle plant that is designed to be deployed in the near term using demonstrated helium system components. The primary system is a conventional pebble bed reactor with a dynamic central column with an outlet temperature of 900 C providing helium to an intermediate helium to helium heat exchanger (IHX). The outlet of the IHX is input to a three shaft horizontal Brayton Cycle power conversion system. The design constraint used in sizing the plant is based on a factory modularity principle which allows the plant to be assembled 'Lego' style instead of constructed piece by piece. This principle employs space frames which contain the power conversion system that permits the Lego-like modules to be shipped by truck or train to sites. This paper also describes the research that has been conducted at MIT since 1998 on fuel modeling, silver leakage from coated fuel particles, dynamic simulation, MCNP reactor physics modeling and air ingress analysis

  1. Success: Richard Dyer on Diana Ross [and Beyond

    NARCIS (Netherlands)

    Kooijman, J.

    2016-01-01

    In June 1982, film scholar Richard Dyer published a two-page essay on African-American star Diana Ross in the journal Marxism Today. Part of Dyer’s essay focuses on the American conception of success and specifically on how Ross is one of the few black artists who has been "allowed" to be such a

  2. Reading 'blackface': A (narrative) introduction to Richard Kearney's ...

    African Journals Online (AJOL)

    Prominent Irish philosopher Richard Kearney's notion of 'carnal hermeneutics' is introduced by applying it to a case study of a recent event that took place at one of South Africa's university campuses. The narrative assists in illuminating some of the core principles of carnal hermeneutics and illustrates the applicability of ...

  3. To Have Been a Student of Richard Feynman

    Indian Academy of Sciences (India)

    Excerpt from Most of the Good Stuff: Memories of Richard Feynman, 1993, ... of Feynman, but while it inspired us to try for originality after we left Cornell, it also lowered our productivity to a point that at times was dangerous to our academic careers. In truth .... (However, my actual thesis topic turned out to be a different one.).

  4. Koht, kust tagasi ei tulda / Mark Jenkins ; fotod Cory Richards

    Index Scriptorium Estoniae

    Jenkins, Mark

    2015-01-01

    National Geographicu ekspeditsiooni, mille koosseisu kuulusid Renan Ozturk, Mark Jenkins, Cory Richards, Emily Harrington ja Kilaree O'Neill, püüdlustest tõusta Kagu-Aasia kõrgeima mäe Hkakabo Razi tippu ning mõõta selle täpset kõrgust GPS-i abil

  5. Whatever Happened to Richard Reid's List of First Programming Languages?

    Science.gov (United States)

    Siegfried, Robert M.; Greco, Daniel M.; Miceli, Nicholas G.; Siegfried, Jason P.

    2012-01-01

    Throughout the 1990s, Richard Reid of Michigan State University maintained a list showing the first programming language used in introductory programming courses taken by computer science and information systems majors; it was updated for several years afterwards by Frances Van Scoy of West Virginia University. However, it has been 5 years since…

  6. In memoriam: Richard (Rick) G. Harrison—benefactor for ...

    Indian Academy of Sciences (India)

    Professor Richard Harrison (1946–2016), a most influential evolutionary biologist of ... were profoundly important in my development as a scientist and a person. ... observations to infer his love of family, but I am going to risk correction by those ...

  7. Biotechnology Process Engineering Center at MIT Home

    Science.gov (United States)

    has provided a focal point for biotechnology research and education at MIT. Prominent examples include the NIH Training Program in Biotechnology and the NIH Training Program in Genomics; both of these are -genomic biology. Another example is the new DuPont-MIT Alliance (DMA), focused on materials biotechnology

  8. Astronomical fire: Richard Carrington and the solar flare of 1859.

    Science.gov (United States)

    Clark, Stuart

    2007-09-01

    An explosion on the Sun in 1859, serendipitously witnessed by amateur astronomer Richard Carrington, plunged telegraphic communications into chaos and bathed two thirds of the Earth's skies in aurorae. Explaining what happened to the Sun and how it could affect Earth, 93 million miles away, helped change the direction of astronomy. From being concerned principally with charting the stars to aid navigation, astronomers became increasingly concerned with what the celestial objects were, how they behaved and how they might affect life on Earth.

  9. Drawings of fossils by Robert Hooke and Richard Waller

    Science.gov (United States)

    Kusukawa, Sachiko

    2013-01-01

    The drawings of fossils by Robert Hooke and Richard Waller that were the basis of the engravings in Hooke's Posthumous works (1705) are published here for the first time. The drawings show that both Hooke and Waller were proficient draftsmen with a keen eye for the details of petrified objects. These drawings provided Hooke with a polemic edge in making the case for the organic origins of ‘figured stones’.

  10. Richard Carwardine and Jay Sexton, eds., The Global Lincoln.

    Directory of Open Access Journals (Sweden)

    Hans Krabbendam

    2012-06-01

    Full Text Available Most countries have their export heroes that transcend their national origin: India has its Ghandi, South Africa its Mandela, England its Churchill, and the US has Abraham Lincoln. While particularly known for his role in the American Civil War, he has developed into an international beacon for liberalism and democracy, especially for nationals deprived of this liberties.This collection of essays, edited by Corpus Christi College (Oxford, UK colleagues Richard Carwardine and Jay Sexton, puts...

  11. When Richard Branson wants to build his own facility

    International Nuclear Information System (INIS)

    Cosnard, D.

    2005-01-01

    The capacity of petroleum refineries is today insufficient to meet the demand. In front of this shortage, Sir Richard Branson, the owner of Virgin Atlantic Airways, has decided to invest in the building of a refinery in Europe or in Canada. His new company, Virgin Oil, is already launched. However, the setting up of a new facility is very expensive and raises important problems of permits and public contestation which remain to be solved. Short paper. (J.S.)

  12. Historical Investigations of the Richard B. Russell Multiple Resource Area.

    Science.gov (United States)

    1981-11-01

    period of this project as a contemporary c~lebration and a reiteration of an ancient folk construction, Stonehenge . Appropriately, as this document goes to...55, 56m, 59m, 64m, 65-68, 71- Stonehenge 216 72, 75-76, 79-84, 84m, 91, 94- Sutch, Richard 20 95, 100, lOlm, 102, 103, 121m, Swift, James Y. 195 126

  13. Response to Richard Widdess: Music, Meaning and Culture

    Directory of Open Access Journals (Sweden)

    Jerome Lewis

    2012-09-01

    Full Text Available This commentary discusses the anthropological implications of Richard Widess’ paper by summarizing some anthropological approaches to music, especially focusing on the way musical participation inculcates and transmits an aesthetic orientation that guides action across cultural domains such as politics, economics and religion. The paper ends by suggesting that the heart of human culture is more likely to be an aesthetic orientation than a script or set of rules, and traces out some reasons why music does this so well.

  14. Richard Wright, Toni Morrison, and United States book clubs

    Directory of Open Access Journals (Sweden)

    Mark Madigan

    2004-12-01

    Full Text Available This essay focuses on the influence of commercial book clubs in the United States. It will examine the country's oldest commercial book club, the Book-of-the-Month Club (BOMC, Oprah's Book Club (OBC, which bears the name of its founder, television personality Oprah Winfrey, and their roles in the careers of two African-American authors, Richard Wright and Toni Morrison.

  15. Bridging the Knowledge Gaps between Richards' Equation and Budyko Equation

    Science.gov (United States)

    Wang, D.

    2017-12-01

    The empirical Budyko equation represents the partitioning of mean annual precipitation into evaporation and runoff. Richards' equation, based on Darcy's law, represents the movement of water in unsaturated soils. The linkage between Richards' equation and Budyko equation is presented by invoking the empirical Soil Conservation Service curve number (SCS-CN) model for computing surface runoff at the event-scale. The basis of the SCS-CN method is the proportionality relationship, i.e., the ratio of continuing abstraction to its potential is equal to the ratio of surface runoff to its potential value. The proportionality relationship can be derived from the Richards' equation for computing infiltration excess and saturation excess models at the catchment scale. Meanwhile, the generalized proportionality relationship is demonstrated as the common basis of SCS-CN method, monthly "abcd" model, and Budyko equation. Therefore, the linkage between Darcy's law and the emergent pattern of mean annual water balance at the catchment scale is presented through the proportionality relationship.

  16. Overview of MIT, ADIP irradiation experiments

    International Nuclear Information System (INIS)

    Kohse, G.; Harling, O.K.; Grant, N.J.

    1985-06-01

    Various rapidly solidified austenitic, ferritic and copper alloys have been produced at MIT for inclusion in ADIP neutron irradiation experiments. A brief summary of the alloys and their preparation and the achieved or projected irradiation parameters is provided

  17. Biotechnology Process Engineering Center at MIT - Overview

    Science.gov (United States)

    | Facsimile (617) 253-2400 | e-mail: bpec-www@mit.edu THERAPEUTIC GENE BIOTECHNOLOGY INDUSTRIAL CONSORTIUM Board (ICAB) in Therapeutic Gene Biotechnology. ICAB Member Representatives review our research progress

  18. MITS Data Acquisition Subsystem Acceptance Test procedure

    International Nuclear Information System (INIS)

    Allison, R.

    1980-01-01

    This is an acceptance procedure for the Data Acquisition Subsystem of the Machine Interface Test System (MITS). Prerequisites, requirements, and detailed step-by-step instruction are presented for inspecting and performance testing the subsystem

  19. When Richard Branson wants to build his own facility; Quand Richard Branson veut construire son propre complexe

    Energy Technology Data Exchange (ETDEWEB)

    Cosnard, D

    2005-10-01

    The capacity of petroleum refineries is today insufficient to meet the demand. In front of this shortage, Sir Richard Branson, the owner of Virgin Atlantic Airways, has decided to invest in the building of a refinery in Europe or in Canada. His new company, Virgin Oil, is already launched. However, the setting up of a new facility is very expensive and raises important problems of permits and public contestation which remain to be solved. Short paper. (J.S.)

  20. MIT research reactor. Power uprate and utilization

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Lin-Wen [Nuclear Reactor Laboratory, Massachusetts Inst. of Technology, Cambridge, MA (United States)

    2012-03-15

    The MIT Research Reactor (MITR) is a university research reactor located on MIT campus. and has a long history in supporting research and education. Recent accomplishments include a 20% power rate to 6 MW and expanding advanced materials fuel testing program. Another important ongoing initiative is the conversion to high density low enrichment uranium (LEU) monolithic U-Mo fuel, which will consist of a new fuel element design and power increase to 7 MW. (author)

  1. Hamlet er manden i mit liv

    DEFF Research Database (Denmark)

    Rösing, Lilian Munk

    2009-01-01

    Hamlet er manden i mit liv. Min elskede. Jeg har en drøm om at frelse ham. At redde ham ud af sin mors soveværelse og ind i mit. Væk fra det ødipale Helvede han befinder sig i, fastlåst mellem et svin af en faderskikkelse (Claudius) og en alt for idealiseret far (gamle Hamlet), vågende over sin m...

  2. Untersuchungen an Eisen- und Lanthanoidhaltigen Koordinationsclustern mit Triazolat- sowie Semiquinonato-Liganden

    OpenAIRE

    Kriese, Thomas

    2016-01-01

    Magnetische Untersuchungen an Lanthanoiddimeren mit Semiquinonato-Liganden. Gemischtvalente Eisen-Koordinationsclustern. Lanthanoid-Koordinationscluster mit zwölf Lanthanoiden aber mit verschiedenen Clusterladungen.

  3. Review of Richard Bausch, Hello to the Cannibals

    Directory of Open Access Journals (Sweden)

    Géraldine Chouard

    2006-03-01

    Full Text Available Richard Bausch is credited with five collections of short stories and nine novels that have received various awards in the United States. His latest work, Hello to the Cannibals, blends a historical epic and a more intimate tale. Watch out‑this is a voracious novel.Other CarnageAn ethnologist investigating cannibalistic rites in Africa asks the head of the tribe : « Do you still have cannibals in your tribe ? » « No, we ate the last one yesterday, » answers the head of the tribe. Undoubtedly,...

  4. [Sir William Richard Gowers: author of the "bible of neurology"].

    Science.gov (United States)

    Hirose, Genjiro

    2014-11-01

    William Richard Gowers is one of the great pioneers in neurology and the author of the well-known neurology textbook, "A Manual of Diseases of the Nervous System." His concepts of neurology are based on meticulously and carefully accumulated knowledge of history, observations, and neurological examinations of patients with various neurological diseases. He is not only a great neurologist but also a great teacher who loves teaching students and physicians through well-prepared lectures. We can glean the essence of the field of neurology through his life story and numerous writings concerning neurological diseases.

  5. "Symposium" by Richard Dawkins, Gerard 't Hooft, Alain Connes

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    Richard Dawkins will speak on biology, Gerard ‘t Hooft will focus on physics, and Alain Connes will discuss mathematics. CERN scientists probe ever-deeper levels of matter and their interactions, but can we say that the patterns they see are truly fundamental? Does the universe obey the same laws throughout? Since mathematical constructions can be true in the absence of any relation to the physical world, is mathematics more fundamental than physics? Extraterrestrial life would probably look much different from that on Earth, but natural selection still be fundamental to their evolution?

  6. Richard Rorty, o la posibilidad de un etnocentrismo universal

    Directory of Open Access Journals (Sweden)

    Isabel Gamero Cabrera

    2010-04-01

    Full Text Available En el presente artículo intentaremos comprender y analizar las implicaciones actuales de dos tesis del filósofo estadounidense Richard Rorty en relación con su etnocentrismo: La expansión global del sistema democrático liberal como horizonte de su teoría política y la restricción de las creencias de importancia última a la esfera privada. Compararemos esta teoría con las aportaciones de otros dos autores: una interpretación antropológica de los juegos de lenguaje de Wittgenstein y la democracia radical de Mouffe.

  7. Free as in Freedom Richard Stallman's Crusade for Free Software

    CERN Document Server

    Williams, Sam

    2011-01-01

    Free as in Freedom interweaves biographical snapshots of GNU project founder Richard Stallman with the political, social and economic history of the free software movement. It examines Stallman's unique personality and how that personality has been at turns a driving force and a drawback in terms of the movement's overall success. Free as in Freedom examines one man's 20-year attempt to codify and communicate the ethics of 1970s era "hacking" culture in such a way that later generations might easily share and build upon the knowledge of their computing forebears. The book documents Stallman'

  8. Minimally invasive thyroidectomy (MIT): indications and results.

    Science.gov (United States)

    Docimo, Giovanni; Salvatore Tolone, Salvatore; Gili, Simona; d'Alessandro, A; Casalino, G; Brusciano, L; Ruggiero, Roberto; Docimo, Ludovico

    2013-01-01

    To establish if the indication for different approaches for thyroidectomy and the incision length provided by means of pre-operative assessment of gland volume and size of nodules resulted in safe and effective outcomes and in any notable aesthetic or quality-of-life impact on patients. Ninehundred eightytwo consecutive patients, undergoing total thyroidectomy, were enrolled. The thyroid volume and maximal nodule diameter were measured by means of ultrasounds. Based on ultrasounds findings, patients were divided into three groups: minimally invasive video assisted thyroidectomy (MIVAT), minimally invasive thyroidectomy (MIT) and conventional thyroidectomy (CT) groups. The data concerning the following parameters were collected: operative time, postoperative complications, postoperative pain and cosmetic results. The MIVAT group included 179 patients, MIT group included 592 patients and CT group included 211 patients. Incidence of complications did not differ significantly in each group. In MIVAT and MIT group, the perception of postoperative pain was less intense than CT group. The patients in the MIVAT (7±1.5) and MIT (8±2) groups were more satisfied with the cosmetic results than those in CT group (5±1.3) (p= MIT is a technique totally reproducible, and easily convertible to perform surgical procedures in respect of the patient, without additional complications, increased costs, and with better aesthetic results.

  9. The Paradox of the Public Realm in Richard Rorty

    Directory of Open Access Journals (Sweden)

    Martha Palacio Avendaño

    2008-12-01

    Full Text Available The concepto of the public sphere in Richard Rorty's philosophy, inherited of liberal tradition, allows be treated as a part of a game of language called democratic liberalism. One of the rules for validating a move in this game consists in taking for granted the distinction between the public and the private spheres. Richard Rorty thought that democratic liberalism did not need any foundation beyond the way to play it; its only criteria would be the game's practices, according an utopia which would allow us to make more movements in the game. That is, democratic liberalism does not require foundations, but just practices for achieving a social hioe inspired on freedom and pluralism. This kind of utopia, based upon the non-cruelty principle, would make possible an inclusive society where everyone would have a place for their own private vocabulary. In this way, Rorty would have linked freedom and solidarity. However, this language-game reveals the paradox of the link which implies the meaning of the public shere. Herein, freedom is not a sufficient condition of solidarity; hence, there is no place for social inclusion in Rorty's language game.

  10. Argument from Design in Richard Baxter's Natural Theology

    Directory of Open Access Journals (Sweden)

    Igor Koshelev

    2017-12-01

    Full Text Available The article deals with the teleological argument, or argument from design, as expounded by a famous English Protestant theologian Richard Baxter, one of the leading 17-th century English Puritans, in his work “The Reasons of the Christian Religion”. Natural theology, providing arguments for the existence of God based on reason and without appeal to the Revelation, has always played a vital role throughout the entire history of theological thought. The most popular was the so called teleological argument, or the argument from design, which stands out among all rational arguments for the existence of the Creator. It is mostly known from the “Fifth Way” of the medieval Scholastic philosopher Thomas Aquinas and a famous work “Natural Theology” by an English 19-th century theologian William Paley. The foundation for the modern research in the area was laid during the age of the Scientific Revolution of the 17th century English nature philosophers and theologians, especially Robert Boyle, who believed the teleological argument to be the key element of Natural Theology. His friend and confessor, Richard Baxter, a prominent representative of the Puritan Natural Theology, mostly known by his theological works, paved the way for Natural Theology both in his own time and the following centuries. His work was thought to be the best collection of the evidences for Christianity.

  11. Prof. Richard Mattessich at 95. His Research Methodology

    Directory of Open Access Journals (Sweden)

    Giuseppe Galassi

    2017-12-01

    Full Text Available This paper is presented as a tribute to prof. Richard Mattessich. It is written “through the eyes” of a researcher who has worked closely with him over a period of 42 years, starting attending his courses of “Income Determination Theory” and “Research Methodology” at the University of British Columbia in 1975. Among his huge scientific research and publications, I intend to underline these three major contributions: (i Accounting metrics and other mathematical instruments which anticipated computer spreadsheet by 30 years; (ii. The preparation of accountants for information economics by means of analytical methods; and (iii The proposition of the “onion model of reality” to distinguish different Kind of reality. Este trabajo se presenta como un tributo al profesor Richard Mattessich. Está escrito “con los ojos” de un investigador que ha trabajado estrechamente con él durante un período de 42 años, comenzando a asistir a sus cursos de " Income Determination Theory" y "Research Methodology" en la Universidad de British Columbia en 1975. Entre su investigación y publicaciones, más importantes pretendo subrayar estas tres contribuciones principales: (i Accounting metrics and other mathematical instruments which anticipated computer spreadsheet by 30 years; (ii The preparation of accountants for information economics by means of analytical methods; y (iii The proposition of the “onion model of reality” to distinguish different Kind of reality.

  12. Swearing Used in Richard Wright’s Black Boy

    Directory of Open Access Journals (Sweden)

    Giyatmi Giyatmi

    2017-07-01

    Full Text Available This research aims at finding the types of swearing expressions and linguistic forms of English swearing used in Richard Wright’s Black Boy. This is a descriptive qualitative research since it describes the phenomena of swearing used in the novel. The data of the research are all the conversations or sentences used swearing in the novel written by Richard Wright namely Black Boy as the main data source. The method of collecting data in this research is observation and teknik lanjut catat. After all the data had been collected then they are coded using the coding system such as data number/title of novel/chapter/page/data. There is no data reduction since all the data are analyzed in this research. This research used theory triangulation. Kind of swearing expressions found in this novel dealing with God and religion terms, name of  animals and plants, part of body, racial terms, stupidity terms, name of occupation, sexual terms, family terms. The linguistic forms of English swearing used in this novel are word, phrase, and clause. The swearing in the form of words consists of (1 noun referring to place, person, occupation, animal, and idea (2 verb and (3 adjective. Phrase consists of (1 noun phrase with swearing functioning as headword, modifier, and both headword and modifier, (2 adjective phrase with swearing functioning as modifier. Swearing expression is also found in the form of sentence.

  13. Review: Lyn Richards (2005. Handling Qualitative Data: A Practical Guide

    Directory of Open Access Journals (Sweden)

    Robert L. Miller

    2006-03-01

    Full Text Available Handling Qualitative Data: A Practical Guide is an introductory textbook covering all stages of qualitative research from the initial conceptualisation of a project, through data collection and analysis, to writing up. The author, Lyn RICHARDS, is a well-known developer of two key qualitative software analysis packages, NUD*IST and NVivo. While RICHARDS clearly advocates the use of qualitative analysis software, the text is "generic" and could be used in tandem with any qualitative software package. The book concentrates on practical advice about the use of software to manage and analyse qualitative data, and provides insights in these areas. The consideration of issues around team-based qualitative research is another strong point. However, due in part to its short length, the overall coverage of topics tends to be superficial. In itself, the book does not provide sufficient detailed support for a student who would like to use it as her/his main source of guidance for carrying out a qualitative research project. URN: urn:nbn:de:0114-fqs0602244

  14. Magnetosphere - Ionosphere - Thermosphere (MIT) Coupling at Jupiter

    Science.gov (United States)

    Yates, J. N.; Ray, L. C.; Achilleos, N.

    2017-12-01

    Jupiter's upper atmospheric temperature is considerably higher than that predicted by Solar Extreme Ultraviolet (EUV) heating alone. Simulations incorporating magnetosphere-ionosphere coupling effects into general circulation models have, to date, struggled to reproduce the observed atmospheric temperatures under simplifying assumptions such as azimuthal symmetry and a spin-aligned dipole magnetic field. Here we present the development of a full three-dimensional thermosphere model coupled in both hemispheres to an axisymmetric magnetosphere model. This new coupled model is based on the two-dimensional MIT model presented in Yates et al., 2014. This coupled model is a critical step towards to the development of a fully coupled 3D MIT model. We discuss and compare the resulting thermospheric flows, energy balance and MI coupling currents to those presented in previous 2D MIT models.

  15. Kompressionstherapie bei Patienten mit Ulcus cruris venosum.

    Science.gov (United States)

    Dissemond, Joachim; Assenheimer, Bernd; Bültemann, Anke; Gerber, Veronika; Gretener, Silvia; Kohler-von Siebenthal, Elisabeth; Koller, Sonja; Kröger, Knut; Kurz, Peter; Läuchli, Severin; Münter, Christian; Panfil, Eva-Maria; Probst, Sebastian; Protz, Kerstin; Riepe, Gunnar; Strohal, Robert; Traber, Jürg; Partsch, Hugo

    2016-11-01

    Wund-D.A.CH. ist der Dachverband deutschsprachiger Fachgesellschaften, die sich mit den Thematiken der Wundbehandlung beschäftigen. Experten verschiedener Fachgesellschaften aus Deutschland, Österreich und der Schweiz haben nun einen aktuellen Konsens der Kompressionstherapie für Patienten mit Ulcus cruris venosum erstellt. In Europa ist das Ulcus cruris venosum eine der häufigsten Ursachen für chronische Wunden. Neben der konservativen und interventionellen Wund- und Venentherapie, ist die Kompressionstherapie die Basis der Behandlungsstrategien. Die Kompressionstherapie kann heute mit sehr unterschiedlichen Materialien und Systemen durchgeführt werden. Während in der Entstauungsphase insbesondere Verbände mit Kurzzugbinden oder Mehrkomponentensysteme zur Anwendung kommen, sind es anschließend überwiegend Ulkus-Strumpfsysteme. Eine weitere, bislang wenig verbreitete Alternative sind adaptive Kompressionsbandagen. Insbesondere für die Rezidivprophylaxe werden medizinische Kompressionsstrümpfe empfohlen. Durch die Vielzahl der heute zur Verfügung stehenden Behandlungsoptionen, kann für nahezu alle Patienten ein Konzept entwickelt werden, dass sich an den individuellen Bedürfnissen und Fähigkeiten orientiert und daher auch akzeptiert und durchgeführt wird. Die Kompressionstherapie ist für die Behandlung von Patienten mit Ulcus cruris venosum essentiell. In den letzten Jahren sind viele verschiedene Therapieoptionen verfügbar, die in den deutschsprachigen Ländern unterschiedlich angewendet oder durchgeführt werden. Daher soll dieser Expertenkonsens dazu beitragen, konkrete Empfehlungen für die praktische Durchführung der Kompressionstherapie von Patienten mit Ulcus cruris venosum darzustellen. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  16. Grosse Axiallager mit Hybridschmierung - Theoretische und experimentelle Betrachtungen

    DEFF Research Database (Denmark)

    Santos, Ilmar; Fuerst, Axel

    2003-01-01

    Der vorliegende Artikel praesentiert die Simulation eines grossen axialen Kippsegmentlagers unter Beruecksichtigung der hybriden Schmierung, d.h. gleichzeitige hydrodynamische und hydrostatische Schmierung. Ein Vergleich mit Messungen zeigt, dass fuer das betrachtete Lager mit 2,2 m Durchmesser die...

  17. Wrestling with Pedagogical Change: The TEAL Initiative at MIT

    Science.gov (United States)

    Breslow, Lori

    2010-01-01

    In the late 1990s, the physics department at the Massachusetts Institute of Technology (MIT) had a problem. The department was responsible for teaching the two required physics courses that are part of the General Institute Requirements (GIRs), MIT's core curriculum--Physics I (mechanics, or in MIT parlance, 8.01) and Physics II (electricity and…

  18. Naturalismo e existencialismo na teoria moral de Richard Hare

    Directory of Open Access Journals (Sweden)

    Marco Antônio Oliveira de Azevedo

    2009-08-01

    Full Text Available http://dx.doi.org/10.5007/1677-2954.2009v8n2p247 Em um artigo de 1966, Amartya Sen procurou mostrar que mesmo Richard Hare, um devoto explícitodo antinaturalismo em ética, ainda que inadvertidamente, incorreu num tipo de naturalismo que Senintitulou de existencial. Neste breve artigo, traço um resumo dessa crítica à teoria de Hare, em especial,da chamada “Lei de Hume”, a qual Sen preferiu apropriadamente intitular “Regra de Hare”. Pretendomostrar como esse tipo peculiar de “existencialismo” nos conduz, ainda que sob o possível protesto deHare e seus seguidores, a conclusões subjetivistas e relativistas sobre a moralidade.

  19. RICHARD WAGNER E O ROMANTISMO ALEMÃO

    Directory of Open Access Journals (Sweden)

    Rainer Câmara Patriota

    2015-07-01

    Full Text Available A cultura musical romântica encontra em Richard Wagner– em sua obra musical e teórica – um de seus maiores protagonistas.A rejeição da Aufklärung e a exaltação da supremacia germânica –elementos constituidores da Weltanschauung romântica alemã –caracterizam fortemente o pensamento e a atitude de Wagner frenteà vida, assumindo conotações ainda mais radicais através de seucontumaz antissemitismo. De modo que pensar Wagner por ocasiãode seu bicentenário também significa retomar uma discussão crucialsobre o romantismo alemão e suas implicações políticas eideológicas.

  20. La paradoja de lo público en Richard Rorty

    Directory of Open Access Journals (Sweden)

    Martha Palacio Avendaño

    2008-01-01

    Full Text Available El concepto de lo público en Richard Rorty, heredero de la tradición liberal, admite ser tratado como parte de un juego del lenguaje denominado liberalismo democrático. En ese sentido, una de las reglas de este juego para saber si una jugada es válida consiste en asumir la distinción entre esfera pública y privada. Richard Rorty pensó que este juego no requería fundamentación más allá de la forma de jugarlo, que el criterio en que se apoyaría estaba en las prácticas que tienen lugar dentro del mismo con arreglo a sostener una utopía que permitiera hacer cada vez más jugadas. Esto es, el liberalismo democrático no requería basarse en algo más allá de las prácticas conducentes a lograr una esperanza social alentada por la libertad en defensa del pluralismo. Su utopía liberal, guiada por el principio de la no-crueldad, haría posible una sociedad inclusiva en la que todos tuvieran espacio para su léxico privado. De este modo, Rorty habría vinculado libertad y solidaridad, pero su juego del lenguaje permite advertir la paradoja del vínculo que implicaría el sentido de lo público. Aquí, la libertad no es condición suficiente de la solidaridad, de modo que la inclusión social no tiene cabida en su juego del lenguaje.

  1. MIT professor wins major international math prize

    CERN Multimedia

    Allen, S

    2004-01-01

    Mathematicians Isadore Singer of MIT and Sir Michael Francis Atiyah of the University of Edinburgh will share an $875,000 award as winners of the second Abel Prize, which some hope will come to be seen as a Nobel Prize for math.

  2. MITS Feed and Withdrawal Subsystem: operating procedures

    International Nuclear Information System (INIS)

    Brown, W.S.

    1980-01-01

    This document details procedures for the operation of the MITS (Machine Interface Test System) Feed and Withdrawal Subsystem (F and W). Included are fill with UF 6 , establishment of recycle and thruput flows, shutdown, UF 6 makeup, dump to supply container, Cascade dump to F and W, and lights cold trap dump, all normal procedures, plus an alternate procedure for trapping light gases

  3. MITS Feed and Withdrawal Subsystem: operating procedures

    International Nuclear Information System (INIS)

    Brown, W.S.

    1980-01-01

    This procedure details the steps involved in filling two of the four MITS (Machine Interface Test System) Feed and Withdrawal subsystem main traps and the Sample/Inventory Make-up Pipette with uranium hexafluoride from the ''AS RECEIVED'' UF 6 supply

  4. Nuclear matter as an MIT bag crystal

    International Nuclear Information System (INIS)

    Zhang, Q.; Derreth, C.; Schaefer, A.; Greiner, W.

    1986-01-01

    An MIT bag crystal model of nuclear matter is formulated. The energy bands of the quarks are calculated as a function of the overlap between adjacent bags. A clear indication of substantial overlap is found. Accordingly, infinite nuclear matter is more similar to a quark gas than to a nucleonic structure. (author)

  5. Editorial 3/2015: Handeln mit Symbolen

    Directory of Open Access Journals (Sweden)

    Alessandro Barberi

    2015-09-01

    Full Text Available Die paradigmatische Unterscheidung zwischen Sozial- und Kulturwissenschaften, die spätestens seit den 1980er Jahren eingehend diskutiert wurde, lässt sich anhand des Bereichs des Symbolischen auf den Punkt bringen: Ist das Symbolische nur ein Effekt von sozialen, ökonomischen oder medialen Strukturen einer gegebenen Gesellschaft oder reproduzieren sich Strukturen nur durch die symbolischen Handlungen der AkteurInnen innerhalb einer gegebenen Kultur? So hatte etwa der klassische "harte" Strukturalismus bei Claude Lévi-Strauss, Jacques Lacan und dem frühen Michel Foucault symbolische Ordnungen (und d. i. hier die Sprache als eine unbewusst determinierende Voraussetzung von menschlicher Interaktion begriffen, woraufhin mit dem Post- bzw. Neostrukturalismus die Rückkehr der individuellen Äußerung, der parole, des speech acts (und d. i. hier das Sprechen, also der symbolischen Handlung in den Mittelpunkt rückte. Medienpädagogisch ist diese Unterscheidung gerade dann von Interesse, wenn es darum geht, wie Lehrende und Lernende sich zueinander verhalten, interagieren und dabei eben mit Symbolen handeln. Insofern ist es bemerkenswert, dass – fast parallel zu Foucaults Unterscheidung von diskursiven und nicht-diskursiven Praktiken – auch Dieter Baacke 1973 von diskursiven und nicht-diskursiven Symbolen gesprochen hat. Denn – wie auch im Rahmen des "Symbolischen Interaktionismus" von George Herbert Mead argumentiert wurde – können Symbole nur im Rahmen einer gegebenen Diskursökonomie von AkteurInnen diskursiv ausgetauscht werden und konstituieren dabei Erfahrungen bzw. Wahrnehmungen und somit auch die soziale bzw. kulturelle Wirklichkeit. Insofern ist die Frage nach dem Symbolischen immer auch eine Frage nach den Möglichkeiten der Handlungstheorie (im Sinne Jürgen Habermas’ bzw. der Praxeologie (im Sinne Pierre Bourdieus. Die Redaktion der MEDIENIMPULSE geht in diesem Zusammenhang theoretisch und praktisch von Entscheidungsimpulse

  6. Redoxspeziation von endlagerrelevanten Elementen mit Hilfe von Trennmethoden gekoppelt an ein Massenspektrometer mit induktiv gekoppeltem Plasma

    OpenAIRE

    Graser, Carl-Heinrich

    2015-01-01

    Im Rahmen dieser Arbeit wurden Redoxspeziationsanalysen von Eisen, Neptunium und Plutonium per CE-SF-ICP-MS durchgeführt. Durch Optimierung der Trennparameter konnten Trennungen der Pu Oxidationsstufen III bis VI und Trennungen der Np Oxidationsstufen IV bis VI binnen 15 Minuten mit einer Nachweisgrenze von 10-12 M durchgeführt werden. Die Trennung der Fe Oxidationsstufen II und III gelang in weniger als 5 Minuten mit einer Nachweisgrenze von 5-10-8 M.

  7. Behandlung von Herzrhythmusstörungen mit Magnesium bei Patienten mit Herzinsuffizienz

    Directory of Open Access Journals (Sweden)

    Wink K

    2002-01-01

    Full Text Available Die medikamentöse Behandlung von Herzrhythmusstörungen ist unbefriedigend, da bei guter Wirksamkeit durch die Proarrhythmie eine Verbesserung der Prognose gefährdet und nicht gesichert ist. Man kann davon ausgehen, daß Magnesiumsalze keine arrhythmogene Effekte aufweisen. Bei Patienten mit einer Herzinsuffizienz besteht häufig ein Mg-Mangel, der durch gastrointestinale Störungen, neurohormonale Regulationen, aber auch durch die Therapie (Diuretika,Digitalisbedingt ist. An Patienten mit einer Herzinsuffizienz müßte sich demnach zeigen lassen, ob die Mg-Substitution einen antiarrhythmischen Effekt aufweist. In fünf placebokontrollierten Studien konnte gezeigt werden, daß sich teil weise signifikant und mit ausreichen der Aussagekraft (PowerArrhythmien bei Patienten mit Herzinsuffizienz durch orale und parenterale Gabe von Mg-Salzen reduzieren lassen. Trotz Einschränkungen wie z.B. inadäquates Design, fehlende Vermeidung von Bias, ungenügende Vergleichbarkeit der Behandlungsgruppen, inadäquate Auswertung und ungenügende Berücksichtigung der Spontanvariation läßt sich aufgrund der Ergebnisse der Studien die Hypothese aufstellen, daß Magnesiumsalze bei Patienten mit Herzinsuffizienz Herzrhythmusstörungen günstig beeinflussen können. Prospektive, randomisierte,verblindete und kontrollierte konfirmatorische Studien mit ausreichenden Fallzahlen sind jedoch notwendig, um diese Hypothese zu bestätigen.

  8. 78 FR 43093 - Richard C. Theuer; Filing of Food Additive Petition and Citizen Petition

    Science.gov (United States)

    2013-07-19

    ... [Docket Nos. FDA-2013-F-0700 and FDA-2013-P-0472] Richard C. Theuer; Filing of Food Additive Petition and... proposing that the food additive regulations be amended to prohibit the use of carrageenan and salts of... that Richard C. Theuer, Ph.D., 7904 Sutterton Ct., Raleigh, NC 27615, has filed a food additive...

  9. 76 FR 10936 - Culturally Significant Objects Imported for Exhibition Determinations: “Richard Serra Drawing: A...

    Science.gov (United States)

    2011-02-28

    ... DEPARTMENT OF STATE [Public Notice: 7348] Culturally Significant Objects Imported for Exhibition Determinations: ``Richard Serra Drawing: A Retrospective'' SUMMARY: Notice is hereby given of the following... objects to be included in the exhibition ``Richard Serra Drawing: A Retrospective,'' imported from abroad...

  10. Travelling wave solutions for the Richards equation incorporating non-equilibrium effects in the capillarity pressure

    NARCIS (Netherlands)

    van Duijn, C. J.; Mitra, K.; Pop, I. S.

    2018-01-01

    The Richards equation is a mathematical model for unsaturated flow through porous media. This paper considers an extension of the Richards equation, where non-equilibrium effects like hysteresis and dynamic capillarity are incorporated in the relationship that relates the water pressure and the

  11. H.E. Mr Richard J. Fredericks, Ambassador of the United States of America to Switzerland

    CERN Document Server

    Patrice Loïez

    2001-01-01

    Photo 01 : Prof. L. Maiani, CERN Director-General, gives a piece of LHC super conducting wire to H.E. Mr. Richard J. Fredericks; Photo 02 : Prof. L. Maiani, CERN Director-General, Mr. Jan van der Boon, CERN Director of Administration and H.E. Mr. J. Richard Fredericks

  12. W. Richard Scott, Institutions and Organizations: Ideas, Interests, and Identities

    DEFF Research Database (Denmark)

    Jakobsen, Michael

    2014-01-01

    Book review of: W. Richard Scott: Institutions and Organizations: Ideas, Interests, and Identities. 4th edition. Thousand Oaks, CA: SAGE Publications, 2014. xiii, 345 pp.......Book review of: W. Richard Scott: Institutions and Organizations: Ideas, Interests, and Identities. 4th edition. Thousand Oaks, CA: SAGE Publications, 2014. xiii, 345 pp....

  13. Grundlegende Steuerungsverfahren im heterogenen Logistiknetz mit Kanban

    Science.gov (United States)

    Dickmann, Eva; Dickmann, Philipp; Lödding, Hermann; Möller, Niklas; Rücker, Thomas; Schneider, Herfried M.; Zäh, Michael F.

    In vielen Unternehmen werden heterogene (verschiedene) Steuerungen in einem abgestimmten Konzept kombiniert. Je nach Anwendungsfall und Rahmenbedingungen werden Kombinationen allgemein bekannter Steuerungen oder Steuerungsvarianten gemischt eingesetzt, um eine optimale Steuerung für unterschiedliche Fälle zu erreichen. Hierbei stehen neben den bekannten und weit verbreiteten Methoden, wie Material Requirements Planning (MRP) oder Kanban, auch weniger bekannte oder neue Methoden zur Auswahl, wie die Produktionssteuerung mit dezentraler, bestandsorientierter Fertigungsregelung (DBF). Kanban ist ein simples und effizientes Steuerungskonzept, das in der klassischen Form für spezifische einfache Anwendungsfälle umsetzbar ist. Hochentwickelte Steuerungsalgorithmen können helfen, komplexe Abläufe optimal abzubilden. Mit einer grundlegenden Vereinfachung der Abläufe kann allerdings in vielen Fällen ein wesentlich stärkerer und umfassender Verbesserungseffekt erzielt werden. Die wesentliche Fragestellung sollte folglich lauten: Warum ist der Ablauf nicht mit einer einfachen Steuerung wie Kanban abzubilden? Um die Vorteile des Konzepts auch in untypischen Bereichen anwenden zu können, sind jedoch verschiedene Varianten oder Kanban-ähnliche Steuerungsmethoden entstanden. Darüber hinaus sind in der Praxis hybride Steuerungen im Einsatz, welche so kombiniert werden, dass die Zusammensetzung anspruchsvolle Eigenschaftsbilder noch exakt abbildet. In der Praxis basieren die Steuerungsentscheidungen nur zu einem kleinen Teil auf den eigentlichen Steuerungsalgorithmen, wie sie uns das MRP-System zur Verfügung stellt. Moderne Steuerungswelten" schließen alle relevanten Informationsquellen in eine heterogene Entscheidungsmatrix mit ein. Letztlich zählt nicht, ob die Entscheidung auf den Informationen aus dem MRP-System oder auf Softfacts basierend getroffen wurde, sondern nur, ob die Entscheidung erfolgreich war.

  14. Untersuchungen zum Potential eines Verbrennungsmotors mit Druckwellenlader

    OpenAIRE

    Binder, Emanuel

    2015-01-01

    Mithilfe der Abgasturboaufladung lässt sich der Kraftstoffverbrauch im Fahrzeugbetrieb durch das Anheben der spezifischen Motorleistung senken. Im Gegensatz zur mechanischen Aufladung verschlechtert sich jedoch mit der Abgasturbolaufladung das Ansprechverhalten. Eine Möglichkeit den Zielkonflikt von Kraftstoffverbrauch und Ansprechverhalten zu lösen ist es, den Abgasturbolader durch einen Druckwellenladers zu ersetzen. Dieser überträgt die Abgasenergie direkt auf die Frischluft in Form von Dr...

  15. The MIT miniaturized disk bend test

    International Nuclear Information System (INIS)

    Harling, O.K.; Lee, M.; Sohn, D.S.; Kohse, G.; Lau, C.W.

    1983-01-01

    A miniaturized disk bend test (MDBT) using transmission electron microscopy specimens for the determination of various mechanical properties is being developed at MIT. Recent progress in obtaining strengths and ductilities of highly irradiated metal alloys is reviewed. Possibilities exist for applying the MDBT approach to the determination of other mechanical properties. Progress in fatigue testing and in determination of the ductile-to-brittle transition temperature is reviewed briefly

  16. Virtuelle Auskunft mit Mehrwert : Chatbots in Bibliotheken

    OpenAIRE

    Christensen, Anne

    2008-01-01

    Die virtuelle Auskunft mit Hilfe elektronischer Informationsassistenten, auch Chatbots oder Chatterbots genannt, ist ein seit dem Jahr 2004 zu beobachtender Trend im deutschen Bibliothekswesen. Die Arbeit stellt die vier Chatbots ASKademicus, Stella, INA und das Sachsen-I vor. Am Beispiel von Stella aus der SUB Hamburg werden dann die Funktionsweise von Chatbots sowie die Anforderungen an die Konzeption dieser virtuellen Berater erläutert. Den Schwerpunkt der Arbeit bilden der Vergleich von C...

  17. Transcendence, Taxis, Trust: Richard Kearney and Jacques Derrida

    Directory of Open Access Journals (Sweden)

    Ulrich Schmiedel

    2017-03-01

    Full Text Available Whatever else it takes to drive a taxi, it takes trust. Day after day, the driver has to decide whether the other is or is not trustworthy. I take the taxi as a test case to analyze and assess Richard Kearney’s diacritical hermeneutics of the other. I argue that Kearney functionalizes the concept of transcendence in order to connect the transcendence of the finite other to the transcendence of the infinite other. However, in his central critique of the deconstructionists following Jacques Derrida, Kearney counters his connection. While Kearney’s critique of Derrida’s account of absolute alterity is correct and compelling, I argue that Derrida’s critique of a distinction between the trustworthy other and the non-trustworthy other might be more crucial than Kearney contends. Insisting on openness to the other’s otherness, Derrida provokes any hermeneutic of the other to trust in transcendence. The taxi is taken as a test to illustrate the implications which diacritical and deconstructive drivers might have for evaluating the entanglement of ethics and eschatology—inside and outside the taxi.

  18. Forjando nuestras democracias: entre Richard Rorty y Vladimiro Montesinos

    Directory of Open Access Journals (Sweden)

    Miguel Giusti

    2001-07-01

    Full Text Available This article aims at explaining the recent history of Peru, in an exercise in which it is possible to extract lessons about the way Latin American democracies have been(or have not been forged. The text draws a parallel between the ideas developed by Richard Rorty in his recently published book, Forjar nuestro país. El pensamiento de izquierdas en los Estados Unidos del siglo XX, and the events in Fugimori's and Montesinos' Peru. If, according to what Rorty believes, "national pride is for the countries what self esteem is for individuals ... " how would it be possible to narrate a history in which there are few motives to be proud of? Trying to escape fatalism and sarcasm, the text tries to show that Montesino's political course is, symbolically, a summary of the decomposition process of Peruvian democracy. Secondly, the text analyses the movements of the political left wing and deals with the support the regimen received from inside and outside the country, a support that was largely based on the illusion of political stability. Finally, it states, as Rorty does, that in order to forge democracies it is necessary for us to be deeply committed to the defense of the State of Right.

  19. Juvenile Cosmology; Or Richard Powers’ Post-Global Doughnut

    Directory of Open Access Journals (Sweden)

    Judith Roof

    2010-02-01

    Full Text Available Le roman de Richard Powers, Operation Wandering Soul (1993, présente le lien subtil qui associe un mondialisme déjà usé et vieillissant à l’enfant perçu comme catégorie dominante. Comme les faces serpentines d’un ruban de Möbius lové autour de l’illimité et de l’intemporel, le texte, tendu entre ses deux infinis – l’univers et l’enfant – révise la portée, la conception, la structure et le style du genre romanesque. Délaissant Aristote pour Einstein, Operation Wandering Soul se place sur le terrain de la cosmologie. Le récit, qui rassemble la kyrielle des grands ralliements juvéniles et leurs vains pèlerinages, concentre l’espace-temps dans une présentation qui évoque la « somme des histoires » de Richard Feynman. La contraction de l’espace-temps opérée par le roman ne fait pas de celui-ci un hymne simpliste au global (catégorie déjà aussi datée que celle des malheureux vétérans du Vietnam, mais capte au contraire la conscience grandissante d’une existence sans origine qui s’étend à perte de vue au-delà de ses coordonnées supposées. Le roman s’enroule sur lui-même tout en s’épanchant au dehors, boucle ses cadres et ses détours tout en desserrant leur emprise. Il fait tourner la roue de ses récits comme des planètes en rotation, la ronde d’un système solaire, le tourbillon d’une galaxie. La conscience que présente Operation Wandering Soul ne se résume donc pas au seul point de vue de l’âme errante qu’est le personnage de Kraft, mais consiste en la somme de tous les temps et de tous les lieux, de leurs strates accumulées comme une conscience en acte, complexe et tissée de réseaux, qui n’appartient à personne et est partagée par tous. Cette accumulation organise le jeu des perspectives multiples qui instaurent l’acte de lecture et sont instaurées par lui. À cet égard, lire constitue ici une physique des oubliés.Richard Powers’ novel Operation Wandering

  20. PolyRES: A polygon-based Richards equation solver

    International Nuclear Information System (INIS)

    Hills, R.G.

    1995-12-01

    This document describes the theory, implementation, and use of a software package designed to solve the transient, two-dimensional, Richards equation for water flow in unsaturated-saturated soils. This package was specifically designed to model complex geometries with minimal input from the user and to simulate groundwater flow related to assessment of low-level radioactive waste disposal sites and engineered facilities. The spatial variation of the hydraulic properties can be defined across individual polygon-shaped subdomains, called objects. These objects combine to form a polygon-shaped model domain. Each object can have its own distribution of hydraulic parameters. The resulting model domain and polygon-shaped internal objects are mapped onto a rectangular, finite-volume, computational grid by a preprocessor. This allows the user to specify model geometry independently of the underlying grid and greatly simplifies user input for complex geometries. In addition, this approach significantly reduces the computational requirements since complex geometries are actually modeled on a rectangular grid. This results in well-structured, finite difference-like systems of equations that require minimal storage and are very efficient to solve. The documentation for this software package includes a user's manual, a detailed description of the underlying theory, and a detailed discussion of program flow. Several example problems are presented that show the use and features of the software package. The water flow predictions for several of these example problems are compared to those of another algorithm to test for prediction equivalency

  1. [Richard Koch's life in national socialism and in Soviet emigration].

    Science.gov (United States)

    Boltres, Daniela; Töpfer, Frank; Wiesing, Urban

    2006-01-01

    The Jewish historian and theorist of medicine, Richard Koch, teaching in Frankfurt/Main, fled in 1936 from National Socialist Germany to the USSR where he lived in the Caucasian spa Essentuki until his death in 1949. Here he worked as a doctor and continued his scientific work, especially on the foundations of medicine in natural philosophy. None of his works of this time were published. Koch was a scientific outsider in the USSR, and he was aware of this. However, he tried to make his views compatible with official doctrines. In 1947 he lost his employment at the medical clinic of Essentuki, and his material situation grew worse. It is still an open question whether this development was related to an increasingly anti-Jewish atmosphere in the USSR that was linked with the Stalinist "purges", as Koch himself appeared to believe. Before his flight from Germany Koch did not show any tendency towards communism or the political left at all. His attitude towards Soviet society and Stalin was mixed: cautious criticism was accompanied by strong expressions of commitment to Stalin and Koch's new Socialist home. The question to what extent Koch's comments showed his true convictions must remain without a definite answer. At least in part they can be understood as precautions in threatening circumstances. The opportunity of a remigration to Germany after 1945, however, was turned down by Koch.

  2. Perception of Leitmotives in Richard Wagner's Der Ring des Nibelungen

    Directory of Open Access Journals (Sweden)

    David J. Baker

    2017-05-01

    Full Text Available The music of Richard Wagner tends to generate very diverse judgments indicative of the complex relationship between listeners and the sophisticated musical structures in Wagner's music. This paper presents findings from two listening experiments using the music from Wagner's Der Ring des Nibelungen that explores musical as well as individual listener parameters to better understand how listeners are able to hear leitmotives, a compositional device closely associated with Wagner's music. Results confirm findings from a previous experiment showing that specific expertise with Wagner's music can account for a greater portion of the variance in an individual's ability to recognize and remember musical material compared to measures of generic musical training. Results also explore how acoustical distance of the leitmotives affects memory recognition using a chroma similarity measure. In addition, we show how characteristics of the compositional structure of the leitmotives contributes to their salience and memorability. A final model is then presented that accounts for the aforementioned individual differences factors, as well as parameters of musical surface and structure. Our results suggest that that future work in music perception may consider both individual differences variables beyond musical training, as well as symbolic features and audio commonly used in music information retrieval in order to build robust models of musical perception and cognition.

  3. Failed Mothers, Monster Sons. Reading Shakespeare’S Richard Iii as a Fairy Tale

    Directory of Open Access Journals (Sweden)

    Percec Dana

    2014-03-01

    Full Text Available The paper looks at Shakespeare’s historical play Richard III and its fairy tale-like character given by the configuration of the main character as an arch-villain and the presence of motifs and patterns typically associated with the fairy tale genre. More specifically, it considers the mother-son relationship between the Duchess of York and Richard in the light of the motif of monstrous birth. It is not a coincidence that the emergence of such motifs coincides with the historical contexts of the early modern period. Reading Richard III in this key is related to the revisionist approach to chronicle plays.

  4. Stand diameter distribution modelling and prediction based on Richards function.

    Directory of Open Access Journals (Sweden)

    Ai-guo Duan

    Full Text Available The objective of this study was to introduce application of the Richards equation on modelling and prediction of stand diameter distribution. The long-term repeated measurement data sets, consisted of 309 diameter frequency distributions from Chinese fir (Cunninghamia lanceolata plantations in the southern China, were used. Also, 150 stands were used as fitting data, the other 159 stands were used for testing. Nonlinear regression method (NRM or maximum likelihood estimates method (MLEM were applied to estimate the parameters of models, and the parameter prediction method (PPM and parameter recovery method (PRM were used to predict the diameter distributions of unknown stands. Four main conclusions were obtained: (1 R distribution presented a more accurate simulation than three-parametric Weibull function; (2 the parameters p, q and r of R distribution proved to be its scale, location and shape parameters, and have a deep relationship with stand characteristics, which means the parameters of R distribution have good theoretical interpretation; (3 the ordinate of inflection point of R distribution has significant relativity with its skewness and kurtosis, and the fitted main distribution range for the cumulative diameter distribution of Chinese fir plantations was 0.4∼0.6; (4 the goodness-of-fit test showed diameter distributions of unknown stands can be well estimated by applying R distribution based on PRM or the combination of PPM and PRM under the condition that only quadratic mean DBH or plus stand age are known, and the non-rejection rates were near 80%, which are higher than the 72.33% non-rejection rate of three-parametric Weibull function based on the combination of PPM and PRM.

  5. AD-1 with research pilot Richard E. Gray

    Science.gov (United States)

    1982-01-01

    Standing in front of the AD-1 Oblique Wing research aircraft is research pilot Richard E. Gray. Richard E. Gray joined National Aeronautics and Space Administration's Johnson Space Center, Houston, Texas, in November 1978, as an aerospace research pilot. In November 1981, Dick joined the NASA's Ames-Dryden Flight Research Facility, Edwards, California, as a research pilot. Dick was a former Co-op at the NASA Flight Research Center (a previous name of the Ames-Dryden Flight Research Facility), serving as an Operations Engineer. At Ames-Dryden, Dick was a pilot for the F-14 Aileron Rudder Interconnect Program, AD-1 Oblique Wing Research Aircraft, F-8 Digital Fly-By-Wire and Pilot Induced Oscillations investigations. He also flew the F-104, T-37, and the F-15. On November 8, 1982, Gray was fatally injured in a T-37 jet aircraft while making a pilot proficiency flight. Dick graduated with a Bachelors degree in Aeronautical Engineering from San Jose State University in 1969. He joined the U.S. Navy in July 1969, becoming a Naval Aviator in January 1971, when he was assigned to F-4 Phantoms at Naval Air Station (NAS) Miramar, California. In 1972, he flew 48 combat missions in Vietnam in F-4s with VF-111 aboard the USS Coral Sea. After making a second cruise in 1973, Dick was assigned to Air Test and Evaluation Squadron Four (VX-4) at NAS Point Mugu, California, as a project pilot on various operational test and evaluation programs. In November 1978, Dick retired from the Navy and joined NASA's Johnson Space Center. At JSC Gray served as chief project pilot on the WB-57F high-altitude research projects and as the prime television chase pilot in a T-38 for the landing portion of the Space Shuttle orbital flight tests. Dick had over 3,000 hours in more than 30 types of aircraft, an airline transport rating, and 252 carrier arrested landings. He was a member of the Society of Experimental Test Pilots serving on the Board of Directors as Southwest Section Technical Adviser in

  6. MIT-Skywalker: On the use of a markerless system.

    Science.gov (United States)

    Goncalves, Rogerio S; Hamilton, Taya; Krebs, Hermano I

    2017-07-01

    This paper describes our efforts to employ the Microsoft Kinect as a low cost vision control system for the MIT-Skywalker, a robotic gait rehabilitation device. The Kinect enables an alternative markerless solution to control the MIT-Skywalker and allows a more user-friendly set-up. A study involving eight healthy subjects and two stroke survivors using the MIT-Skywalker device demonstrates the advantages and challenges of this new proposed approach.

  7. Optimierung der Hupkraftverteilung eines airbagintegrierten Automobillenkrades mit Hilfe einer Parameterstudie

    OpenAIRE

    Pietsch, Karsten

    2011-01-01

    Die Hupkraftverteilung eines airbagintegrierten Automobillenkrades wird mit Hilfe einer Parameterstudie in MathCAD so optimiert, das an jeder Krafteinleitungsposition die Hupe mit einer geforderten Mindestkraft betätigt werden kann. Nach der Modellierung in MathCAD der zugehörigen Geometrie und der Dimensionierung der Federlagerung ist das zugehörige mechanische Ersatzmodell mit Hilfe einer Parameterstudie verändert worden, so dass die Hupkraftforderung erfüllt wird.

  8. [Bernt Ahrenholz : Verweise mit Demonstrativa im Gesprochenen Deutsch...] / Klaus Geyer

    Index Scriptorium Estoniae

    Geyer, Klaus

    2008-01-01

    Arvustus: Ahrenholz, Bernt. Verweise mit Demonstrativa im gesprochenen Deutsch : Grammatik, Zweitspracherwerb und Deutsch als Fremdsprache. Berlin ; New York : de Gruyter, 2007. (Linguistik - Impulse & Tendenzen ; 17)

  9. Lendab nagu kotkas üle maailmas kogutud tarkuse / Richard Aroksaar ; intervjueerinud Ene Riet

    Index Scriptorium Estoniae

    Aroksaar, Richard

    2014-01-01

    Intervjuu eestlase Richard Aroksaarega, kes õppinud psühholoogiat ja raamatukogundust, töötab USA Rahvusparkide Ühenduse raamatukogus (National Park Service Library, NPS) süsteemi raamatukoguhoidja ja administraatorina

  10. Richard Kelly: Pioneirismo na iluminação da arquitetura moderna

    Directory of Open Access Journals (Sweden)

    Fernanda Brito Bandeira

    2018-04-01

    Full Text Available Livros resenhado: NEUMANN, Dietrich; STERN, Robert A. M. The structure of light: Richard Kelly and the illumination of modern architecture. New York: Yale University Press, 2010, 214 p. ISBN: 978-0-300-16370-4

  11. EDITORIAL: Richard Palmer: celebrating 37 years with Journal of Physics: Condensed Matter Richard Palmer: celebrating 37 years with Journal of Physics: Condensed Matter

    Science.gov (United States)

    Ferry, David

    2009-01-01

    It is with a great deal of both happiness and sadness that I have to announce that we are losing one of the real strengths of the Journal of Physics: Condensed Matter (JPCM). Dr Richard Palmer, our Senior Publisher, announced his retirement, and this issue marks the first without his involvement. Of course, we are happy that he will get to enjoy his retirement, but we are sad to lose such a valuable member of our team. Richard first started work at IOP Publishing in March 1971 as an Editorial Assistant with Journal of Physics B: Atomic and Molecular Physics. After a few months, he transferred to Journal of Physics C: Solid State Physics. During his first year, he was sent on a residential publishing training course and asked to sign an undertaking to stay at IOP Publishing for at least two years. Although Richard refused to sign, as he did not want to commit himself, he has remained with the journal since then. The following year, the Assistant Editor of Journal of Physics C: Solid State Physics, Malcolm Haines, walked out without notice in order to work on his family vineyard in France, and Richard stepped into the breach. In those days, external editors had a much more hands-on role in IOP Publishing and he had to travel to Harwell to be interviewed by Alan Lidiard, the Honorary Editor of Journal of Physics C: Solid State Physics, before being given the job of Assistant Editor permanently. I am told that in those days the job consisted mainly of editing and proofreading and peer review. There was no journal development work. At some point in the early 1980s, production and peer review were split into separate departments and Richard then headed a group of journals consisting of Journal of Physics C: Solid State Physics, Journal of Physics D: Applied Physics and Journal of Physics F: Metal Physics, Semiconductor Science and Technology, Superconductor Science and Technology, Plasma Physics and Controlled Fusion, and later Nanotechnology and Modelling and Simulation

  12. MIT - Mighty Steps toward Energy Sustainability

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, Alastair [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Regnier, Cindy [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Settlemyre, Kevin [Sustainable IQ, Inc., Arlington, MA (United States); Bosnic, Zorana [HOK, San Francisco, CA (United States)

    2012-07-01

    Massachusetts Institute of Technology (MIT) partnered with the U.S. Department of Energy (DOE) to develop and implement solutions to retrofit existing buildings to reduce energy consumption by at least 30% as part of DOE’s Commercial Building Partnerships (CBP) Program.1 Lawrence Berkeley National Laboratory (LBNL) provided technical expertise in support of this DOE program. MIT is one of the U.S.’s foremost higher education institutions, occupying a campus that is nearly 100 years old, with a building floor area totaling more than 12 million square feet. The CBP project focused on improving the energy performance of two campus buildings, the Ray and Maria Stata Center (RMSC) and the Building W91 (BW91) data center. A key goal of the project was to identify energy saving measures that could be applied to other buildings both within MIT’s portfolio and at other higher education institutions. The CBP retrofits at MIT are projected to reduce energy consumption by approximately 48%, including a reduction of around 72% in RMSC lighting energy and a reduction of approximately 55% in RMSC server room HVAC energy. The energy efficiency measure (EEM) package proposed for the BW91 data center is expected to reduce heating, ventilation, and air-conditioning (HVAC) energy use by 30% to 50%, depending on the final air intake temperature that is established for the server racks. The RMSC, an iconic building designed by Frank Gehry, houses the Computer Science and Artificial Intelligence Laboratory, the Laboratory for Information and Decision Systems, and the Department of Linguistics and Philosophy.

  13. Obituary: Richard L. (Dick) Walker, Jr., 1938-2005

    Science.gov (United States)

    Pier, Jeffrey R.; Mason, Brian

    2005-12-01

    Koch Center for Science, Math, and Technology at Deerfield Academy in Massachusetts. He also consulted with James Turrell, providing astronomical position information for the design of the Roden Crater Project outside of Flagstaff. While he will be remembered for his significant scientific contributions to the field of astronomy, those who knew Dick, both scientists and non-scientists alike, will probably remember him best for his humility, his humanity, and his loyal and abiding friendship. He was a man with a terrific sense of humor and an infectious laugh. It was always an honor and pleasure to be in his company. Richard L. Walker, Jr. is survived by his wife, Patricia, two daughters from his first marriage: Brenda Walker of Las Vegas, NV, and Pamela Hepburn of Holland, OH, as well as four children from Patricia's first marriage: Doug Browning of Lake Havasu City, AZ, Michael Browning of Kingman, AZ, Kim Bructo of Orient, OH, and Jennifer Brown of Lake Havasu City, AZ. He is also survived by ten grandchildren and three great-grandchildren. He was preceded in death by his father Richard, mother Mary, and daughter, Paula Jean Elizabeth Stone.

  14. Thyroid hemiagenesis with immunthyropathy; Schilddruesenhemiagenesie mit Immunthyreopathie

    Energy Technology Data Exchange (ETDEWEB)

    Mikosch, P.; Gallowitsch, H.J.; Kresnik, E.; Lind, P. [Landeskrankenhaus Klagenfurt (Austria). Abt. fuer Nuklearmedizin und Spezielle Endokrinologie

    1999-06-01

    A case of Graves` disease occurring in a patient with hemiagenesis is presented. The detection of the rare occurrence of a congential hemiagenesis is often made by either clinical symptoms of thyroid dysfunction or anatomical abnormalities such as nodular goiter. The symptoms of hyperthyroidism in the current case led to the diagnostic confirmation by scintiscanning and ultrasonography of an absent lobe. Anti-thyroid antibody studies documented the presence of Graves` disease within the remaining lobe. (orig.) [Deutsch] Die Hemiagenesie der Schilddruese stellt eine seltene angeborene Veraenderung dar. Diese angeborene Variante der Schilddruesenanlage wird in den meisten Faellen durh Auffaelligkeiten der Funktion oder der Groesse des vorhandenen Schilddruesenlappens zufaellig gefunden. Der Fall einer 57jaehrigen Frau mit einer Schilddruesenhemiagenesie in Kombination mit einer Immunthyreopatie Basedow wird vorgestellt. Die Zuweisung der Patientin zur Untersuchung erfolgte wegen einer Schilddruesenueberfunktion. Die erforderlichen diagnostischen Schritte zur Erstellung dieser beiden Schilddruesenveraenderungen waren ein 99m-Tc-Schilddruesenszintigramm, Ultraschall und Laborparameter der Schilddruese (fT4, TT3, bTSH, TAK, TPO, TRAK). (orig.)

  15. Physik gestern und heute: Visualisierung mit der Schlierenmethode

    Science.gov (United States)

    Heering, Peter

    2006-07-01

    Der Name des österreichischen Forschers Ernst Mach ist heute noch mit der Schallgeschwindigkeit verbunden. Diese Auszeichnung resultiert aus Machs Untersuchungen, wie sich Projektile mit Überschallgeschwindigkeit durch die Luft bewegen. Gerade in jüngster Zeit hat die Anwendung derartiger Methoden durch technische Modifikationen wieder einen Aufschwung erfahren.

  16. MACH MIT: Deutsches Wochenende am Karlsfluss (MACH MIT: a German Week-End on the Charles River).

    Science.gov (United States)

    Reizes, Sonia; Kramsch, Claire J.

    1980-01-01

    Describes a joint high school/college pilot program planned by Massachusetts foreign language teachers and hosted by M.I.T. The success of the program dubbed "MACH MIT Total Immersion German Weekend" is attributed to the concept of active involvement, which was implemented through games, seminars, shows, cooking and other activities.…

  17. Kunden- und wettbewerbsorientierte Produktentwicklung mit QFD: Kundenorientierte Produktentwicklung mit Hilfe von Quality Function Deployment (QFD)

    OpenAIRE

    Schloske, Alexander

    2013-01-01

    Die Produktentwicklung von heute muss in immer kürzeren Zeiträumen kunden- und kostenorientierte Produkte entwickeln. Zur systematischen Unterstützung dieser Aufgabe im Rahmen der Produktentwicklung wird die Methode Quality Function Deployment (QFD) eingesetzt. Die konsequente Umsetzung der Stimme des Kunden in die Sprache des Unternehmens gelingt mit Quality Function Deployment (QFD). Die Methode wertet systematisch Kundenanforderungen an Produkte aus und führt zu innovativen Lösungen, die s...

  18. Peniskarzinom mit exulzerierten Lymphknotenmetastasen links inguinal

    Directory of Open Access Journals (Sweden)

    Presich K

    2003-01-01

    Full Text Available Im Oktober 2001 wurde ein 53jähriger Patient mit ausgedehnten exulzerierten Lymphknotenmetastasen rechts inguinal an einer auswärtigen chirurgischen Abteilung vorgestellt. Im Rahmen der Durchuntersuchung fand sich eine verhärtete, von einem nicht retrahierbaren Präputium verdeckte Glans als mögliches Primum. Eine Circumcision sowie Biopsie aus der Glans ergaben das histologische Ergebnis eines invasiven, schwach verhornenden Plattenepithelkarzinoms mittleren Differenzierungsgrades (G2-G3. In einer Unterbauch-Computertomographie wurde rechts inguinal ein ausgedehnter, ca. 10 cm messender, teils solider, teils nekrotischer Prozeß, bis an die großen Gefäße heranreichend, beschrieben. Die linke Leiste war unauffällig.

  19. Current activities at the MIT Research Reactor

    International Nuclear Information System (INIS)

    Hu Linwen; Bernard, John A.; Harling, Otto K.; Kohse, Gordon E.; Ames, Michael; Olmez, Ilhan

    1998-01-01

    The MIT Research Reactor (MITR) is a MW nuclear research reactor that is owned and operated by the Massachusetts Institute of Technology to further its educational and research goals at both the undergraduate and graduate level. The reactor first achieved criticality in 1958. It was largely rebuilt in 1973/1974 by MIT staff and students, and its current license expires in August 1999. The current facility, which is designated as the MITR-H, uses a compact core with finned, aluminum-clad, plate-type fuel that is cooled and moderated by light water and reflected by heavy water. The reactor core can hold twenty-seven fuel elements. However, the normal configuration is twenty-four elements. A maximum of four fuel elements can be replaced with in-core experimental facilities. A unique feature of the MITR-II's design is that fixed absorber plates can be inserted in the upper half of the core. These cause the flux to peak in the lower half which benefits experimenters and also facilitates a fuel strategy that involves inversion of fuel elements midway through their life cycle. The MITR-II currently operates continuously for four weeks followed by shutdown of a few days for maintenance. This paper provides an overview of current activities at the MITR including preparations for re-licensing. The status of an on-going Phase-I clinical trial of boron neutron capture therapy for both glioblastoma multiforme and metastatic melanoma is described as well as the design of a fission converter facility for BNCT. Environmental research using neutron activation analysis is summarized as well as in-pile research focussed on LWR water chemistry and structural materials. (author)

  20. Teaching ``The Physics of Energy'' at MIT

    Science.gov (United States)

    Jaffe, Robert

    2009-05-01

    New physics courses on energy are popping up at colleges and universities across the country. Many require little or no previous physics background, aiming to introduce a broad audience to this complex and critical problem, often augmenting the scientific message with economic and policy discussions. Others are advanced courses, focussing on highly specialized subjects like solar voltaics, nuclear physics, or thermal fluids, for example. About two years ago Washington Taylor and I undertook to develop a course on the ``Physics of Energy'' open to all MIT students who had taken MIT's common core of university level calculus, physics, and chemistry. By avoiding higher level prerequisites, we aimed to attract and make the subject relevant to students in the life sciences, economics, etc. --- as well as physical scientists and engineers --- who want to approach energy issues in a sophisticated and analytical fashion, exploiting their background in calculus, mechanics, and E & M, but without having to take advanced courses in thermodynamics, quantum mechanics, or nuclear physics beforehand. Our object was to interweave teaching the fundamental physics principles at the foundations of energy science with the applications of those principles to energy systems. We envisioned a course that would present the basics of statistical, quantum, and fluid mechanics at a fairly sophisticated level and apply those concepts to the study of energy sources, conversion, transport, losses, storage, conservation, and end use. In the end we developed almost all of the material for the course from scratch. The course debuted this past fall. I will describe what we learned and what general lessons our experience might have for others who contemplate teaching energy physics broadly to a technically sophisticated audience.

  1. Trochanteric fractures. Classification and mechanical stability in McLaughlin, Ender and Richard osteosynthesis

    Energy Technology Data Exchange (ETDEWEB)

    Herrlin, K.; Stroemberg, T.; Lidgren, L.; Walloee, A.; Pettersson, H.

    Four hundred and thirty trochanteric factures operated upon with McLaughlin, Ender or Richard's osteosynthesis were divided into 6 different types based on their radiographic appearance before and immediately after reposition with special reference to the medial cortical support. A significant correlation was found between the fracture type and subsequent mechanical complications where types 1 and 2 gave less, and types 4 and 5 more complications. A comparison of the various osteosyntheses showed that Richard's had significantly fewer complications than either the Ender or McLaughlin types. For Richard's osteosynthesis alone no correlation to fracture type could be made because of the small number of complications in this group.

  2. Final Technical Report for the MIT Annular Fuel Research Project

    International Nuclear Information System (INIS)

    Mujid S. Kazimi; Pavel Hejzlar

    2008-01-01

    MIT-NFC-PR-082 (January 2006) Abstract This summary provides an overview of the results of the U.S. DOE funded NERI (Nuclear Research Energy Initiative) program on development of the internally and externally cooled annular fuel for high power density PWRs. This new fuel was proposed by MIT to allow a substantial increase in power density (on the order of 30% or higher) while maintaining or improving safety margins. A comprehensive study was performed by a team consisting of MIT (lead organization), Westinghouse Electric Corporation, Gamma Engineering Corporation, Framatome ANP(formerly Duke Engineering) and Atomic Energy of Canada Limited

  3. MIT gets good marks for fighting gender discrimination

    Science.gov (United States)

    Gwynne, Peter

    2011-05-01

    The Massachusetts Institute of Technology (MIT) has made "significant progress" in increasing the number of female faculty members, with their numbers in science and engineering almost doubling over the last decade.

  4. Behandlung des chronischen Tinnitus mit repetitiver transkranieller Magnetstimulation

    OpenAIRE

    Kleinjung, T

    2012-01-01

    Tinnitus ist eine Funktionsstörung des Hörsystems, die von verschiedenen Strukturen und Ebenen ausgehen kann. Tinnitus geht mit neuroplastischen Veränderungen im zentralen auditorischen System einher. Existenz eines „Tinnitus-Netzwerkes“.

  5. Laser mit instabilem Resonator fuer ringfoermige aktive Medien

    OpenAIRE

    Jarosch, U.K.; Habich, U.; Plum, H.D.

    1996-01-01

    Beschrieben werden Laser mit instabilen Resonatoren, die ringfoermige Medien effektiv ausnutzen, unabhaengig davon, ob es sich um feste, fluessige oder gasfoermige Medien handelt. Die Erfindung zeichnet sich dadurch aus, dass die Auskopplung des Strahles (5.1) eines Ringresonators entlang eines Spaltes oder eines Kreisringes ueber dem gesamten Umfang vorgesehen ist, wobei der Laserresonator durch Ringspiegel (1,2) mit torusfoermiger Spiegelflaeche gebildet und von den Waenden des Ringspaltes ...

  6. MIT CSAIL and Lincoln Laboratory Task Force Report

    Science.gov (United States)

    2016-08-01

    funded through MIT LL, most notably through by the MIT LL Technology Office (TO). TO funding has come through a diverse set of venues: ASD (R&E) Line...many and varied opportunities to participate could better cohere research interests at each institution and between them as well. 3.4.2 Autonomy-at...applications. Near-data processing is about migrating selected processing operations from the central processing unit (CPU) of traditional computer

  7. Molekulargenetische Charakterisierung einer Familie mit Usher-Syndrom

    OpenAIRE

    Zimmer, AJ; Arndt, S; Aschendorff, A; Birkenhäger, R

    2009-01-01

    Einleitung: Das Usher-Syndrom definiert eine genetisch und klinisch heterogene autosomal rezessiv vererbte Erkrankung mit dem gleichzeitigen Auftreten von Innenohrschwerhörigkeit bis hin zur Taubheit, teilweise Vestibularisausfall und Netzhautdegeneration (Retinitis Pigmentosa). Bisher wird das Usher-Syndrom in drei verschiedene Hauptgruppen (USH1-3) mit unterschiedlicher phänotypischer Ausprägung eingeteilt. Für das Usher-Syndrom sind 12 Genorte bekannt, für die bereits acht Gene identifizi...

  8. A geometrodynamical approach to the MIT confinement scheme

    International Nuclear Information System (INIS)

    Martellini, M.; Sodano, P.

    1978-01-01

    Starting from the strong gravity theory of Salam-Isham-Strathdee the M.I.T. bag is identified as a certain region of the global extension of a De Sitter-Schwarzschild solution. As a result the M.I.T. bag radius, a geometrical interpretation of the binding Lagrangian term and a rate of decaying of the ''bag manifold'' into the flat space (which, however, does not lead to observable quark wave functions) are obtained. (author)

  9. Quasi-constitutional change without intent : A response to Richard Albert

    NARCIS (Netherlands)

    Passchier, Reijer

    2017-01-01

    Recently, Buffalo Law Review published Richard Albert’s article on “quasi-constitutional amendments.” These are, in Albert’s words, “sub-constitutional changes that do not possess the same legal status as a constitutional amendment, that are formally susceptible to statutory repeal or revision, but

  10. Ripples from a Passing Ship: Memories; and a Legacy of Richard Peters

    Science.gov (United States)

    Harris, Kevin

    2013-01-01

    This paper outlines aspects and dimensions of my "relationship" with Richard Peters from 1966 onward. The underlying suggestion is that, while Peters' contribution to philosophy of education was undeniably of major proportions, both that contribution and his legacy are institutional rather than substantive. (Contains 15 notes.)

  11. Racial Shame and the Pleasure of Transformation: Richard Rodriguez's Queer Aesthetics of Assimilation

    Science.gov (United States)

    Beltran, Cristina

    2012-01-01

    This essay analyzes Latino conservative thought by rethinking the logics of assimilation through a simultaneous exploration of aesthetic possibility and negative affect. Focusing on the writings of Richard Rodriguez, the essay considers how creative forms of self-individuation and political agency cannot easily be decoupled from negative forms of…

  12. Richard Rorty's Conception of Philosophy of Education Revisited

    Science.gov (United States)

    Noaparast, Khosrow Bagheri

    2014-01-01

    In this essay Khosrow Bagheri Noaparast argues that, by focusing on acculturation and edification, Richard Rorty has provided a promising view for education because without acculturation, education turns into a destructive endeavor, and without edification, education risks the danger of being repetitive and reproductive. However, Rorty's view…

  13. Richard Wright's Thematic Treatment of Women in "Uncle Tom's Children,""Black Boy," and "Native Son."

    Science.gov (United States)

    Brewton, Butler E.

    Richard Wright's literary work emphasizes a contrast between black women and white women. Although both are "givers" to black boys, the nature of what they give is different. The black woman gives physical life, feeds it, and protects it at the expense of spiritual or creative vitality. Her goal is to survive bodily, to breathe, to have…

  14. Understanding Richard Wright's "Black Boy": A Student Casebook to Issues, Sources, and Historical Documents.

    Science.gov (United States)

    Felgar, Robert

    In "Black Boy," Richard Wright triumphs over an ugly, racist world by fashioning an inspiring, powerful, beautiful, and fictionalized autobiography. To help students understand and appreciate his story in the cultural, political, racial, social, and literary contexts of its time, this casebook provides primary historical documents,…

  15. Süütuse kaotamine / Richard Branson ; intervjueerinud Peter Fisk ; tõlkinud Endrik Randoja

    Index Scriptorium Estoniae

    Branson, Richard

    2009-01-01

    Turunduskirjanik Peter Fiski intervjuu Suurbritannia ärimagnaadi Sir Richard Bransoniga, milles arutletakse ettevõtja suurimate saavutuste ja suurimate pettuste üle, uuritakse Bransoni võimet juhtida oma 450 ettevõtet, tema suhtumist konkurentsi ning uutesse äriideedesse, samuti tema ajakasutust

  16. Transforming Faith: H. Richard Niebuhr and Paulo Freire on Moral Education

    Science.gov (United States)

    Daniel, Joshua Leonard

    2013-01-01

    Through a contextual comparison of the theological ethics of H. Richard Niebuhr and the educational theory of Paulo Freire, I argue that socialization, while an essential task of moral education, is an insufficient aim. The proper aim of moral education is individual development. The intention of my argument is address tendencies towards…

  17. Resisting Biopolitics through “Diaphanous Wonder”: Richard Flanagan's Gould's Book of Fish

    NARCIS (Netherlands)

    Wiese, Doro|info:eu-repo/dai/nl/304842699

    2014-01-01

    In Gould's Book of Fish (2003), author Richard Flanagan manages to invent a format in which content and style account for historical events on Sarah Island, Tasmania in the 1820s, yet he does so in a manner that is not in the least objective, disinterested or fact-orientated. The perspective of

  18. Somaesthetic Training, Aesthetics, Ethics, and the Politics of Difference in Richard Shusterman's "Body Consciousness"

    Science.gov (United States)

    Powell, Kimberly

    2010-01-01

    In this essay, the author first addresses the theme of disciplined somatic training and its relationship to self-awareness and transformation. Her attention is focused specifically on the chapter on Ludwig Wittgenstein, in which Richard Shusterman presents and then elaborates upon the philosopher's connections between conscious bodily feelings and…

  19. Astronaut Richard H. Truly in training session RMS for STS-2 bldg 9A

    Science.gov (United States)

    1981-01-01

    Astronaut Richard H. Truly in training session with the Remote Manipulator System (RMS) for STS-2 bldg 9A. Views show Truly working at the command console while watching out the windows. Karen Ehlers, an RMS procedures specialist, can be seen at left side of frame (34314); view from behind Truly as he trains at the RMS console (34315).

  20. Strauss, Richard. Ariane a Naxos: opera seulement, integrale. Miliza Korjus / Michel Parouty

    Index Scriptorium Estoniae

    Parouty, Michel

    1995-01-01

    Uuest heliplaadist "Strauss, Richard. Ariane a Naxos: opera seulement, integrale. Miliza Korjus (Najade). Orchestre de l'Opea l'Efat de Vienne" Arlecchino ARL 14-16, distribution Dante (3 CD: 390 F). 1935, 1944. TT: 3h 46'17"

  1. Fluid flow in porous media using image-based modelling to parametrize Richards' equation.

    Science.gov (United States)

    Cooper, L J; Daly, K R; Hallett, P D; Naveed, M; Koebernick, N; Bengough, A G; George, T S; Roose, T

    2017-11-01

    The parameters in Richards' equation are usually calculated from experimentally measured values of the soil-water characteristic curve and saturated hydraulic conductivity. The complex pore structures that often occur in porous media complicate such parametrization due to hysteresis between wetting and drying and the effects of tortuosity. Rather than estimate the parameters in Richards' equation from these indirect measurements, image-based modelling is used to investigate the relationship between the pore structure and the parameters. A three-dimensional, X-ray computed tomography image stack of a soil sample with voxel resolution of 6 μm has been used to create a computational mesh. The Cahn-Hilliard-Stokes equations for two-fluid flow, in this case water and air, were applied to this mesh and solved using the finite-element method in COMSOL Multiphysics. The upscaled parameters in Richards' equation are then obtained via homogenization. The effect on the soil-water retention curve due to three different contact angles, 0°, 20° and 60°, was also investigated. The results show that the pore structure affects the properties of the flow on the large scale, and different contact angles can change the parameters for Richards' equation.

  2. Making the Road While Walking It: A Conversation with Richard Simpson

    Science.gov (United States)

    Zabel, Robert H.; Kaff, Marilyn; Teagarden, James

    2016-01-01

    Richard Simpson is professor of special education at the University of Kansas (KU). Dr. Simpson's duties at KU have included roles of staff psychologist, teaching associate, assistant professor, project director, associate professor, professor, and chairperson for the Department of Special Education. He has directed numerous University of Kansas…

  3. 75 FR 53730 - Culturally Significant Objects Imported for Exhibition Determinations: “Richard Hawkins-Third Mind”

    Science.gov (United States)

    2010-09-01

    ... DEPARTMENT OF STATE [Public Notice 7148] Culturally Significant Objects Imported for Exhibition Determinations: ``Richard Hawkins--Third Mind'' SUMMARY: Notice is hereby given of the following determinations... the exhibition ``Richard Hawkins--Third Mind,'' imported from abroad for temporary exhibition within...

  4. Rigiscan®-Monitoring der Erektion unter audiovisueller sexueller Stimulation ohne/mit Viagra™ bei Patienten mit erektiler Dysfunktion

    Directory of Open Access Journals (Sweden)

    Perabo FGE

    2000-01-01

    Full Text Available Die orale Medikation mit Sildenafil (Viagra™ hat sich zur Therapie der erektilen Dysfunktion etabliert und relativiert die Differentialdiagnose zwischen psychogener und organischer Dysfunktion mit den entsprechenden therapeutischen Konsequenzen. Diesem Problem widmet sich diese Studie zur Prüfung der erektilen Antwort unter RigiScan®-Monitoring ohne/mit 50 mg Viagra™. 64 Patienten (mittleres Alter 48 Jahre mit einer erektilen Dysfunktion arteriogener (n = 10, venöser (n = 7, gemischt neurogen/vaskulärer (n = 15 und psychogener (n = 32 Genese von mehr als 6 Monaten Dauer wurden in die Studie aufgenommen. Alle Patienten wurden eingehend diagnostisch abgeklärt, inklusive Hormonlabor, dynamischer Pharmako-Duplexsonographie und, falls indiziert, mit einer Cavernosometrie/ -graphie. Zur Testung der penilen Rigidität und zur Objektivierung der Erektion wurde das "real-time" RigiScan® verwendet. In zwei konsekutiven Messungen wurden sowohl die direkte erektile Antwort auf visuelle Stimulation als auch die nächtlichen Erektionen abgeleitet und die Meßergebnisse mit den Begleiterkrankungen, "lifestyle"-Faktoren und dem Ergebnis der Pharmako-Duplexsonographie korreliert. Es fand sich keine Korrelation zwischen der Ätiologie der erektilen Dysfunktion in bezug auf organische oder psychogene Genese und dem Alter der Patienten, der Dauer der Erektionsstörung, dem Nikotinabusus, den Blutfetten, den Testosteronwerten, dem klinischen Ergebnis der Pharmakotestung (Erektionsgrad und dem duplexsonographisch gemessenen Fluß der penilen Arterien. Hingegen zeigte sich eine positive Korrelation zwischen Genese der erektilen Dysfunktion (organisch bzw. psychogen und dem RigiScan®-Meßergebnis (r = 0,29. Patienten mit psychogen bedingter Erektionsstörung profitierten am meisten von Viagra™, während Patienten mit vaskulärer Genese oder gemischt neurogener/vaskulärer Genese deutlich schlechter auf Viagra™ ansprachen. Es bestand keine Korrelation

  5. Technical realization of a closure concept for a chamber-system in the underground Richard repository in the Czech Republic

    International Nuclear Information System (INIS)

    Kucerka, Miroslav

    2006-01-01

    The Phare project CZ 632.02.04 'Realization of closure of a chamber in the Richard repository as input for establishing a safety case' is a follow up implementation phase of the Phare project, CZ 01.14.03 'Solution for closure of a chamber in the Richard repository'. Main objective of both projects is to propose and realize a disposal system in selected chambers of the Richard repository, which will eliminate burden from the past practices in waste management during the first phase of the Richard repository operation (1965 - 1980) and which will improve its overall long term safety. This objective will be assured by realization of the concept of so called 'hydraulic cage', which technical solution was developed by DBE Technology within the Phare project CZ 01.14.03. The solution is described in the previous presentation 'Hydraulic Cage Concept for Waste Chambers and its Technical Implementation for the Underground Richard Repository, Litomerice, Czech Republic'. (author)

  6. Prospect of mechanical engineering. Report from MIT; Kikai kogaku no atarashii tenkai. MIT kara no hokoku

    Energy Technology Data Exchange (ETDEWEB)

    Asada, H [Massachusetts Inst. of Technology, Cambridge, MA (United States)

    1996-01-05

    The author of this article is a professor of Department of Mechanical Engineering of Massachusetts Institute of Technology (MIT) and the director general of Laboratory for Information Systems and Technology of the institute. At Department of Mechanical Engineering of Engineering Faculty of world-famous MIT, Laboratory for Information Systems and Technology was established in 1994 and in the same year, the curricula of the department were greatly revised after 30 years for its enforcement from the new semester starting from September, 1995. These two occasions are suggestive for guessing the future of mechanical engineering, hence its aim and meaning are introduced. Department of Mechanical Engineering aims to bring up system integrators who can consolidate systems based on wide-ranged knowledge, and its basic subjects are divided into 4 subjects namely dynamics and control, heat and fluid, system engineering and control, and design and production, and it has been decided that each of them is taught in equal weight and in parallel. Also as a new study field in the above Department of Mechanical Engineering, nanotechnology and artificial intelligence, and high-technological aircraft and networks are shown as examples.

  7. [Postoperative adjuvante Therapie mit einem Mistelextrakt (Viscum album ssp. album) bei Hündinnen mit Mammatumoren].

    Science.gov (United States)

    Biegel, Ulrike; Stratmann, Nina; Knauf, Yvonne; Ruess, Katja; Reif, Marcus; Wehrend, Axel

    2017-01-01

    Hintergrund: Canine Mammatumoren (CMT) sind wegen ihrer Häufigkeit und hohen Malignitätsrate eine Herausforderung für die Veterinärmedizin. Bisher ist noch keine postoperative adjuvante Therapie als wirksamer Standard etabliert und in den nächsten Jahren wohl auch nicht zu erwarten. Zusätzlich ist die Frage nach der Verträglichkeit einer adjuvanten Therapie mit Erhaltung oder Verbesserung der Lebensqualität (LQ) wichtig. Die Therapie mit Mistelextrakten (Viscum album L.; VAE) ist in der Humanonkologie nach adjuvanter Tumorbasistherapie (Chemotherapie und Bestrahlung) eine sehr häufig verwendete, zusätzliche adjuvante Behandlungsmethode. Auch bei verschiedenen Tierarten werden inzwischen Mistelpräparate in der Onkologie erfolgreich angewendet. Methoden: Überprüfung von Wirkung und Nutzen einer postoperativen, adjuvanten Misteltherapie beim CMT sowie Erfassung der LQ unter der VAE-Behandlung. Ausgewertet wurden 56 Hündinnen mit Mammaadenokarzinom, 33 ausschließlich operierte Kontrolltiere und 23 operierte Tiere, die adjuvant VAE erhielten. Ergebnisse: Die mediane Überlebenszeit (MST) aller Tiere (n = 56) betrug 32 Monate (Interquartilbereich 13-51 Monate). Im deskriptiven Vergleich der Überlebenszeiten (ST) nach Kaplan-Meier waren nach 12, 24, 36 bzw. 48 Monaten noch 24, 20, 15 bzw. 5 Hündinnen (entsprechend 72,7%, 60,6%, 45,1%, 12,4%) der Kontrollgruppe sowie 19, 14, 11 und 1 Hündin (82,6%, 60,9%, 47,8%, 4,3%) der VAE-Gruppe am Leben. Die VAE-Therapie führte zu einem geringeren Gesamtversterberisiko, das statistisch nicht signifikant war (Hazard Ratio (HR) 0,530, 95%-Konfidenzintervall (KI) 0,222-1,262; p = 0,15). Tendenziell (p = 0,07) zeigte sich eine Verringerung des tumorbedingten Sterberisikos auf 25% (HR 0,251, 95%-KI 0,056-1,122). Schlussfolgerungen: Es kann eine Tendenz zur Senkung des tumorbedingten Sterberisikos der VAE-Gruppe bei guter Verträglichkeit der Therapie angenommen werden. Die LQ der Tiere blieb über die gesamte

  8. The micro turbine: the MIT example; La micro turbine: l'exemple du MIT

    Energy Technology Data Exchange (ETDEWEB)

    Ribaud, Y. [Office National d' Etudes et de Recherches Aerospatiales (ONERA-DEFA), 92 - Chatillon (France)

    2001-10-01

    The micro turbine study began a few years ago at the MIT, with the participation of specialists from different fields. The purpose is the development of a MEMS (micro electro mechanical systems) based, 1 cm in diameter, micro gas turbine. Potential applications are devoted to micro drone propulsion, electric power generation for portable power sources in order to replace heavy Lithium batteries, satellite motorization, the surface distributed power for boundary suction on plane wings. The manufacturing constraints at such small scales lead to 2-D extruded shapes. The physical constraints stem from viscous effects and from limitations given by 2-D geometry. The time scales are generally shorter than for conventional machines. Otherwise the material properties are better at such length scales. Transposition from conventional turbomachinery laws is no more applicable and new design methods must be established. The present paper highlights the project progress and the technology breakthroughs. (author)

  9. Islam, Migration und Integration: Konflikte jugendlicher Migranten mit islamischem Hintergrund

    Directory of Open Access Journals (Sweden)

    Ilhan Kizilhan

    2008-04-01

    Full Text Available Der Islam mit seinen verschiedenen Verhaltensweisen und Verboten spielt direkt oder indirekt immer noch eine wichtige Rolle im alltäglichen Leben vieler Migranten. Religiöse Vorschriften zeichnen sich dadurch aus, dass ihrer Achtung nicht juristisch, sondern durch sozialen Druck Nachdruck verliehen wird (Verwandtschaft, religiöse Lehrer, islamische Gemeinde, religiöse Vereine etc. und dass ihre Missachtung mit Folgen in Form von Ausgrenzung, Missachtung und Diskriminierung einhergeht. Die kulturellen Vorstellungen der ersten Generation unterscheiden sich auf Grund der unterschiedlichen Biografien von denen der zweiten und dritten durch den Grad der Verwurzelung in der kulturellen Identität und der Verbundenheit mit traditionellen Wertvorstellungen. Fehlende Integrationskonzepte, Ausgrenzung im Migrationsland auf der einen und weltweite staatliche und halbstaatliche Konflikte im Namen des Islams bis hin zum Terrorismus auf der anderen Seite haben einen erheblichen Einfluss auf den Integrationsgrad von jugendlichen Migranten im Aufnahmeland.

  10. Professionell entwickeln mit Java EE 7 das umfassende Handbuch

    CERN Document Server

    Salvanos, Alexander

    2014-01-01

    Ein praxisorientiertes Lehrbuch zur JEE 7 und zugleich ein Standardwerk, das Sie auf Ihrem Weg zum Enterprise-Entwickler begleitet. Inklusive Best Practices für leichtgewichtige Enterprise Applications, Standards zu servicebasierten Anwendungen, Persistence API, Dependency Injection, HTML5 und Performance-Tuning. Aus dem Inhalt: Grundlagen und Installation Software-Architektur mit Java EE Webanwendungen mit HTML5 und CSS3 Java Standard Tag Library Asynchrone Servlets und Non-blocking I/O Datenbanken anbinden mit der JDBC API Java Server Faces Datenbank-Organisation Java Persistence API Objektrelationales Mapping Transaktionssicherheit Performance-Tuning Internationalisierung Enterprise Java Beans WebSockets PrimeFaces Deployment Galileo Press heißt von jetzt an Rheinwerk Verlag.

  11. Richard III in Russian Theatre at the Twilight of the "Thaw"

    OpenAIRE

    Sokolyansky, Mark

    2007-01-01

    Richard III was very rarely staged in Russian theatre in tsarist and Stalin’s times, because the story of inhuman tyranny provoked associations with Russian political reality. In the period of the so-called “Thaw” (1954ß1964) the play became very popular in the USSR and several scenic productions of it were real events in Russian (and Soviet) theatrical life. In the essay three most original and successful performances (in Kujbyshev, Gorkij and Erevan) are discussed and compare...

  12. Missing Kettles and Too Few Toasters: The Forecasting Methodology at Morphy Richards

    OpenAIRE

    Lane, D; Hughes, D

    2002-01-01

    Faced with problems in forecasting at Morphy Richards, this research represents an investigation into their forecasting methodology following the hypothesis that the current forecasting system was no longer sufficient to ensure guaranteed supply to customers, or to enable forward planning.\\ud \\ud The purpose of the research was to identify any requirements for change within the forecasting system and to identify the ‘best practice’ within the industry. Primary research was carried out using a...

  13. Richard J. Bernstein on Ethics and Philosophy between the Linguistic and the Pragmatic Turn

    OpenAIRE

    Marchetti, Sarin

    2017-01-01

    1. In his compelling article American Pragmatism: The Conflict of Narratives, Richard Bernstein quotes a perceptive line by Alasdair MacIntyre that goes [A] tradition not only embodies the narrative of an argument, but is only recovered by an argumentative retelling of that narrative which will itself be in conflict with other argumentative retellings. Bernstein, in the essay mentioned, works through MacIntyre’s passage in order to “engage in the ‘argumentative retelling’ of a metanarrative –...

  14. Il concetto di medium artistico: Richard Wollheim interprete di Ludwig Wittgenstein

    OpenAIRE

    Maistrello, Andrea

    2016-01-01

    The aim of the dissertation is twofold: (i) analyzing the notion (well known by aestheticians, but not so intensively studied) of artistic medium; (ii) showing the relevance of such notion for aesthetics through the examination of some relevant aspects of Richard Wollheim’s philosophy of art, maybe the main figure in Anglo-American philosophy as for considering artistic medium central in art-theorizing. Artistic media, according to Wollheim, can develop only if properly connected to a cultura...

  15. Selfish memes: An update of Richard Dawkins’ bibliometric analysis of key papers in sociobiology

    OpenAIRE

    Aaen-Stockdale, Craig

    2017-01-01

    This is an Open Access journal available from http://www.mdpi.com/ In the second edition of The Selfish Gene, Richard Dawkins included a short bibliometric analysis of key papers instrumental to the sociobiological revolution, the intention of which was to support his proposal that ideas spread within a population in an epidemiological manner. In his analysis, Dawkins primarily discussed the influence of an article by British evolutionary biologist William Donald Hamilton which had introdu...

  16. Metaforos populiarojo mokslo literatūroje: Richard Dawkins knygos analizė

    OpenAIRE

    Urbanavičiūtė, Dovilė

    2017-01-01

    The following paper discusses metaphor usage in the genre of popular science. The object of this analysis is a chapter called ‘Immortal coils’ taken from Richard Dawkins’ book The Selfish Gene. The study discusses the impact of creative conceptual metaphors on the construction of the overall meaning of the text, as well as the significance of their linguistic manifestations and context. In focusing on the genre of popular science, it also makes an attempt at defining potential difficulties of...

  17. Pimping climate change: Richard Branson, global warming, and the performance of green capitalism

    OpenAIRE

    Scott Prudham

    2009-01-01

    On 21 September 2006 UK über-entrepreneur and Virgin Group Chairman Richard Branson pledged approximately £1.6 billion, the equivalent of all the profits from Virgin Atlantic and Virgin Trains for the next ten years, to fighting climate change. Since then, Branson has restated his commitment to action on global warming, including investment in technologies for sequestering carbon dioxide from the atmosphere. In this paper, I critically examine and engage with Branson’s announcements as a spec...

  18. Fallstudie SIG - Supply Chain Prototyp mit Coca Cola Beverages

    OpenAIRE

    Senger, Enrico

    2003-01-01

    SIG, ein führender Lieferant von Verpackungsmaterialien für Getränke, hat mit Coca Cola CPFR, collaborative planning, forecasting and replenishment realisiert. Das Unternehmen kann elektronisch und ohne Zeitverzug (vorher mit bis zu 15 Tagen Verspätung) auf die Lagerbestände und Verkaufsvorhersagen bei Coca Cola zugreifen. Coca Cola erhält die exakten Liefermengen und zeiten. Coca Cola konnte dadurch den Lagerbestand von Verpackungsmaterial um 50% senken. Dies reduziert die Bearbeitungszeit d...

  19. Untersuchungen zur Farbreaktion von Amilorid, Chlorhexidin und Proguanil mit Hypobromit

    OpenAIRE

    Huth, Silke

    2004-01-01

    Bei der Reaktion von Amiloridhydrochlorid (1· HCl) mit Brom in alkalischer Lösung wird ein gelbbraunes Dehydrierungsprodukt erhalten, daß als 3-(3-Amino-1,2,4-oxadiazol-5-yl)-5-chlor-2,6-pyrazindiamin (6) identifiziert werden konnte. Durch Vergleich von Massen- und NMR-Spektren der Verbindung 6 mit Spektren von 1· HCl und Referenzsubstanzen I-III konnte auf die verbindung 6 geschlossen werden. Die Struktur wurde durch eine Röntgenstrukturanalyse abgesichert. Erhitzen von Amiloridhydrochlorid ...

  20. Hinderniserkennung und -verfolgung mit einer PMD-kamera im automobil

    Science.gov (United States)

    Schamm, Thomas; Vacek, Stefan; Natroshvilli, Koba; Marius Zöllner, J.; Dillmann, Rüdiger

    Die Detektion von Hindernissen vor dem Automobil ist eine Hauptanforderung an moderne Fahrerassistenzsysteme (FAS). In dieser Arbeit wird ein System vorgestellt, das mit Hilfe einer PMDKamera (Photomischdetektor) Hindernisse auf der Fahrspur erkennt und deren relevante Parameter bestimmt. Durch die PMD-Kamera werden zunächst 3D-Tiefenbilder der Fahrzeugumwelt generiert. Nach einem initialen Filterprozess werden im Tiefenbild mit Hilfe eines Bereichswachstumsverfahrens Hindernisse gesucht. Zur Stabilisierung des Verfahrens und zur Parameterberechnung wird ein Kaiman Filter eingesetzt. Das Ergebnis ist eine Liste aller Hindernisse im Fahrbereich des Automobils.

  1. Richard Watson.

    Science.gov (United States)

    Wright, Ian; Bevin, William

    2017-11-25

    An inspirational equine veterinary surgeon with a keen interest in racing, to whom horses were a way of life. He took much pride in the success of his homebred racehorses. British Veterinary Association.

  2. Richard Rorty

    DEFF Research Database (Denmark)

    Hjermitslev, Hans Henrik

    2016-01-01

    dekonstruktion forlod han Princeton og blev han i 1982 udnævnt til professor i humaniora ved University of Virginia. Her skrev han i 1989 sit andet hovedværk Contingency, Irony, and Solidarity, der med originale læsninger af Heidegger, Derrida, Orwell, Nabokov, Freud og andre blev modtaget med stor interesse...

  3. Untersuchungen zum Riechvermögen bei Patienten mit schizophrenen Störungen

    OpenAIRE

    Minovi, A; Dombrowski, T; Brüne, M; Dazert, S; Juckel, G

    2014-01-01

    Einleitung: Riechstörungen werden bei Patienten mit einer Schizophrenie in vielen Studien beschrieben. Im Rahmen einer prospektiv angelegten Studie untersuchten wir das Riechvermögen von 18 Patienten mit einer Schizophrenie im Vergleich zu einer Kontrollgruppe (n=13). Weiterhin erfolgte eine immunhistochemische Untersuchung der Riechschleimhaut bei 8 Patienten mit einer Schizophrenie.Methoden: Die Riechprüfung erfolgte mit Hilfe der erweiterten Sniffin' Sticks-Testbatterie. Nach Biopsie der...

  4. Book Review of Relational Patterns, Therapeutic Presence: Concepts and practice of Integrative Psychotherapy by Richard G. Erskine

    Directory of Open Access Journals (Sweden)

    Marye O'Reilly-Knapp

    2015-12-01

    Full Text Available Book Review of Relational Patterns, Therapeutic Presence: Concepts and practice of Integrative Psychotherapy by Richard G. Erskine. Published by Karnac Books: London, 2015 Paperback, Pages 366, ISBN 13: 978-1-78220-190-8

  5. Book Review of Relational Patterns, Therapeutic Presence: Concepts and practice of Integrative Psychotherapy by Richard G. Erskine

    OpenAIRE

    Marye O'Reilly-Knapp

    2015-01-01

    Book Review of Relational Patterns, Therapeutic Presence: Concepts and practice of Integrative Psychotherapy by Richard G. Erskine. Published by Karnac Books: London, 2015 Paperback, Pages 366, ISBN 13: 978-1-78220-190-8

  6. Parallelization experience with four canonical econometric models using ParMitISEM

    NARCIS (Netherlands)

    Baştürk, N.; Grassi, S.; Hoogerheide, L.; van Dijk, H.K.

    2016-01-01

    This paper presents the parallel computing implementation of the MitISEM algorithm, labeled Parallel MitISEM. The basic MitISEM algorithm, introduced by Hoogerheide et al. (2012), provides an automatic and flexible method to approximate a non-elliptical target density using adaptive mixtures of

  7. Parallelization Experience with Four Canonical Econometric Models Using ParMitISEM

    NARCIS (Netherlands)

    N. Basturk (Nalan); S. Grassi (Stefano); L.F. Hoogerheide (Lennart); H.K. van Dijk (Herman)

    2016-01-01

    textabstractThis paper presents the parallel computing implementation of the MitISEM algorithm, labeled Parallel MitISEM. The basic MitISEM algorithm, introduced by Hoogerheide, Opschoor and Van Dijk (2012), provides an automatic and flexible method to approximate a non-elliptical target density

  8. Parallelization experience with four canonical econometric models using ParMitISEM

    NARCIS (Netherlands)

    Bastürk, Nalan; Grassi, S.; Hoogerheide, L.; van Dijk, Herman K.

    2016-01-01

    This paper presents the parallel computing implementation of the MitISEM algorithm, labeled Parallel MitISEM. The basic MitISEM algorithm provides an automatic and flexible method to approximate a non-elliptical target density using adaptive mixtures of Student-t densities, where only a kernel of

  9. MIT wavelength tables. Volume 2. Wavelengths by element

    International Nuclear Information System (INIS)

    Phelps, F.M. III.

    1982-01-01

    This volume is the first stage of a project to expand and update the MIT wavelength tables first compiled in the 1930's. For 109,325 atomic emission lines, arranged by element, it presents wavelength in air, wavelength in vacuum, wave number and intensity. All data are stored on computer-readable magnetic tape

  10. MIT Orients Course Materials Online to K-12

    Science.gov (United States)

    Cavanagh, Sean

    2008-01-01

    Many science and mathematics educators across the country are taking advantage of a Web site created by the Massachusetts Institute of Technology (MIT), the famed research university located in Cambridge, Massachusetts, which offers free video, audio, and print lectures and course material taken straight from the school's classes. Those resources…

  11. MIT Mints a Valuable New Form of Academic Currency

    Science.gov (United States)

    Carey, Kevin

    2012-01-01

    The Massachusetts Institute of Technology (MIT) has invented or improved many world-changing things--radar, information theory, and synthetic self-replicating molecules, to name a few. Last month the university announced, to mild fanfare, an invention that could be similarly transformative, this time for higher education itself. It is called MITx.…

  12. Possibilities of transport with monorails; Moeglichkeiten des Transports mit Einschienenhaengebahnen

    Energy Technology Data Exchange (ETDEWEB)

    Bolz, P. [Deutsche Montan Technologie GmbH, Bochum (Germany)

    2001-08-02

    The safety limits of transport by monorails were determined within the framework of a test project. The safety-related components of the system, in particular the rail system with its suspensions and the drive and braking system, were investigated for normal and heavy load transport. In addition to operational measurements for actual stressing of the components tests were conducted on test benches to determine the dynamic strength. The concept of a new forward-looking monorail system with greater safety was subsequently developed with the aid of the results obtained. The compatibility with the previous components was ensured. Compared to the determined load capacity limits a development requirement for monorail suspension anchor bolts, diesel- and battery-operated trolleys as well as braking trolleys for ropeways were derived. The other components are already adequately dimensioned. (orig.) [German] Im Rahmen eines Untersuchungsvorhabens wurden die sicherheitlichen Grenzen des Transports mit EHB ermittelt. Die sicherheitsrelevanten Bauteile des Systems, insbesondere das Schienensystem mit seinen Aufhaengungen sowie das Antriebs- und Bremssystem, wurden fuer den Normal- und den Schwerlasttransport untersucht. Neben Betriebsmessungen zur tatsaechlichen Beanspruchung der Bauteile erfolgten Pruefstandsuntersuchungen zur dynamischen Festigkeit. Mit Hilfe der gewonnenen Ergebnisse wurde anschliessend das Konzept fuer ein neues, zukunftsorientiertes EHB-System mit erhoehter Sicherheit erarbeitet. Die Kompatibilitaet zu den bisherigen Bauteilen wurde dabei gewaehrleistet. Im Vergleich zu den ermittelten Belastbarkeitsgrenzen wurde daraus ein Entwicklungsbedarf bei EHB-Aufhaengeankern, Diesel- und Batteriekatzen sowie Bremskatzen fuer Seilbahnen abgeleitet. Die uebrigen Bauteile sind bereits jetzt ausreichend bemessen. (orig.)

  13. Interaktion mit virtuellen Agenten? Zur Aneignung eines ungewohnten Artefakts

    DEFF Research Database (Denmark)

    Krummheuer, Antonia Lina

    sprechen, schließt der soziologische Interaktionsbegriff nichtmenschliche Gesprächspartner aus. Es stellt sich daher die Frage, mit welchen Konzepten die Soziologie dieses neue Phänomen fassen kann. Vor dem Hintergrund der techniksoziologischen Debatte um die Handlungsträgerschaft von Artefakten werden die...

  14. Collimator optimization studies for the new MIT epithermal neutron beam

    International Nuclear Information System (INIS)

    Riley, K.J.; Ali, S.J.; Harling, O.K.

    2000-01-01

    A patient collimator has been designed for the epithermal neutron facility now being commissioned at MIT. Collimator performance both in and out of field was evaluated using the Monte Carlo code MCNP. A two piece design that can accommodate different circular field sizes will be manufactured using a composite lead, epoxy, boron and lithium mixture. (author)

  15. Interaktion mit RFID Ausleih- und Rückgabeautomaten

    DEFF Research Database (Denmark)

    Greifeneder, Elke; Heyroth, Melanie; Klingbeil, Karin

    2011-01-01

    Der Artikel untersucht mittels Beobachtung die Interaktion zwischen RFID-Ausleih- und Rückgabeautomaten sowie Bibliotheksbenutzern in vier deutschen Bibliotheken. Die Ergebnisse belegen, dass die Interaktion grundsätzlich funktioniert. Die Benutzer zeigten Gelassenheit und Routine im Umgang mit den...

  16. Chronisch-dekompensierter Tinnitus: ein heterogenes Krankheitsbild mit Auswirkungen auf den Behandlungserfolg

    OpenAIRE

    Ivansic, D; Müller, B; Dobel, C; Guntinas-Lichius, O

    2017-01-01

    Einleitung: Bei etwa 5% der Patienten mit chronischem Tinnitus gehen die Ohrgeräusche mit erheblichem Leidensdruck, häufig auch mit psychiatrischen Störung einher. Da es aktuell keine wirksame Behandlung gibt, welche zu Beseitigung des chronischen Tinnitus führt, ist das Therapieziel die Reduktion der Tinnitus-Belastung. Methodik: Es wurden von 7/13 bis 12/14 308 Patienten mit chronischen Tinnitus tagesklinisch interdisziplinär behandelt. Die Tinnitus-Belastung wurde mit Tinnitus-Fragebogen...

  17. Richard Rufus's theory of mixture: a medieval explanation of chemical combination.

    Science.gov (United States)

    Weisberg, Michael; Wood, Rega

    2003-05-01

    Richard Rufus of Cornwall offered a novel solution to the problem of mixture raised by Aristotle. The puzzle is that mixts or mixed bodies (blood, flesh, wood, etc.) seem to be unexplainable through logic, even though the world is full of them. Rufus's contribution to this long-standing theoretical debate is the development of a modal interpretation of certain Averroistic doctrines. Rufus's account, which posits that the elemental forms in a mixt are in accidental potential, avoids many of the problems that plagued non-atomistic medieval theories of mixture. This paper is an initial examination of Rufus' account.

  18. An experimental ‘Life’ for an experimental life : Richard Waller's biography of Robert Hooke (1705)

    OpenAIRE

    Moxham, Noah

    2016-01-01

    Richard Waller's ‘Life of Dr Robert Hooke’, prefixed to his edition of Hooke's Posthumous Works (1705), is an important source for the life of one of the most eminent members of the early Royal Society. It also has the distinction of being one of the earliest biographies of a man of science to be published in English. I argue that it is in fact the first biography to embrace the subject's natural-philosophical work as the centre of his life, and I investigate Waller's reasons for adopting thi...

  19. Of poetics and possibility: Richard Kearney’s post-metaphysical God

    Directory of Open Access Journals (Sweden)

    Yolande Steenkamp

    2017-11-01

    Full Text Available This article provides an overview of Richard Kearney’s attempt at re-imagining God post-metaphysically. In the context of a continental dialogue on the topic, Kearney has responded to onto-theology with a hermeneutic and phenomenologically informed attempt to rethink God post-metaphysically. This eschatological understanding of God is expounded in the article and is placed in relation to Kearney’s more recent concept of Anatheism. The article closes with a few remarks on what may be gained by Kearney’s work, as well as outlining a few critical questions.

  20. Popular science - common ground. A literary critique of Richard Dawkins's The Selfish Gene

    OpenAIRE

    Nilsen, Helene

    2012-01-01

    This thesis aims to perform a literary reading of Richard Dawkins's The Selfish Gene from a perspective situated outside of the 'battle of the two cultures'. Chapter 1 takes Foucault's article What is an author?" as its point of departure. After discussing how Dawkins may be seen as a reader of Darwin, I will go on to discuss Foucault's concept of the author-function, before I move on to consider some different readings of and approaches to The Selfish Gene. With reference to a polemic bet...

  1. Diagnosis and treatment of polycystic ovary syndrome (PCOS): an interview with Richard Legro.

    Science.gov (United States)

    Legro, Richard

    2015-03-27

    In this podcast, we talk to Professor Richard Legro about the recommendations for the diagnosis and treatment of polycystic ovary syndrome (PCOS) based on clinical practice guidelines and discuss the challenges of diagnosis PCOS at specific age groups. The controversies associated with treatment of PCOS, including therapies for infertility as this is a problem commonly observed in PCOS subjects, are highlighted together with future directions on the topic. The podcast for this interview is available at. http://www.biomedcentral.com/content/supplementary/s12916-015-0299-2-s1.mp3.

  2. Leachate flow around a well in MSW landfill: Analysis of field tests using Richards model.

    Science.gov (United States)

    Slimani, R; Oxarango, L; Sbartai, B; Tinet, A-J; Olivier, F; Dias, D

    2017-05-01

    During the lifespan of a Municipal Solid Waste landfill, its leachate drainage system may get clogged. Then, as a consequence of rainfall, leachate generation and possibly leachate injection, the moisture content in the landfill increases to the point that a leachate mound could be created. Therefore, pumping the leachate becomes a necessary solution. This paper presents an original analysis of leachate pumping and injection in an instrumented well. The water table level around the well is monitored by nine piezometers which allow the leachate flow behaviour to be captured. A numerical model based on Richards equation and an exponential relationship between saturated hydraulic conductivity and depth is used to analyze the landfill response to pumping and injection. Decreasing permeability with depth appears to have a major influence on the behaviour of the leachate flow. It could have a drastic negative impact on the pumping efficiency with a maximum quasi-stationary pumping rate limited to approximately 1m 3 /h for the tested well and the radius of influence is less than 20m. The numerical model provides a reasonable description of both pumping and injection tests. However, an anomalous behaviour observed at the transition between pumping and recovery phases is observed. This could be due to a limitation of the Richards model in that it neglects the gas phase behaviour and other double porosity heterogeneous effects. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Wooing-Scenes in “Richard III”: A Parody of Courtliness?

    Directory of Open Access Journals (Sweden)

    Agnieszka Stępkowska

    2009-11-01

    Full Text Available In the famous opening soliloquy of Shakespeare’s Richard III, Richard mightily voices his repugnance to “fair well-spoken days” and their “idle pleasures”. He realizes his physical deformity and believes that it sets him apart from others. He openly admits that he is “not shaped for sportive tricks, nor made to court an amorous looking-glass”. Yet, his monstrosity constitutes more perhaps of his aggressive masculine exceptionality rather than of his deformity. Richard’s bullying masculinity manifests itself in his contempt for women. In the wooing scenes we clearly see his pugnacious pursuit of power over effeminate contentment by reducing women to mere objects. Additionally, those scenes are interesting from a psychological viewpoint as they brim over with conflicting emotions. Therefore, the paper explores two wooing encounters of the play, which belong the best examples of effective persuasion and also something we may refer to as ‘the power of eloquence’.

  4. Construction of Fluid - solid Coupling Model with Improved Richards - BP & Its Engineering Application

    Science.gov (United States)

    Xie, Chengyu; Jia, Nan; Shi, Dongping; Lu, Hao

    2017-10-01

    In order to study the slurry diffusion law during grouting, Richards unsaturated-saturated model was introduced, the definition of the grouting model is clear, the Richards model control equation was established, And the BP neural network was introduced, the improved fluid-solid coupling model was constructed, Through the use of saturated - unsaturated seepage flow model, As well as the overflow boundary iterative solution of the mixed boundary conditions, the free surface is calculated. Engineering practice for an example, with the aid of multi - field coupling analysis software, the diffusion law of slurry was simulated numerically. The results show that the slurry diffusion rule is affected by grouting material, initial pressure and other factors. When the slurry starts, it flows in the cracks along the upper side of the grouting hole, when the pressure gradient is reduced to the critical pressure, that is, to the lower side of the flow, when the slurry diffusion stability, and ultimately its shape like an 8. The slurry is spread evenly from the overall point of view, from the grouting mouth toward the surrounding evenly spread, it gradually reaches saturation by non-saturation, and it is not a purely saturated flow, when the slurry spread and reach a saturated state, the diffusion time is the engineering grouting time.

  5. Gamma radiation and radon concentration levels at the radioactive waste repositories 'Richard' and 'Bratrstvi'

    International Nuclear Information System (INIS)

    Berka, Z.; Sabol, J.; Janu, M.

    1998-01-01

    Owing to the fact that cosmic rays are shielded off, the photon equivalent dose rates in the corridors of the Richard repository are usually slightly lower than outside. However, in points close to barrels containing radioactive waste, the dose rates can reach values as high as tens of μSv/h. Because of high concentrations of natural radionuclides, the dose rates in the Bratrstvi repository is generally considerably higher, as much as 5 times the normal background value. Radon concentrations exhibit specific time variations which are modified by ventilation. Where ventilation is poor or absent, the radon concentrations are extremely high, viz. up to 30 and 300 kBq/m 3 in the Richard and Bratrstvi repositories, respectively. Personal exposure of workers depend on the total time spent underground and on the ventilation rate. While the contribution from photons can be kept below the relevant limits, the radon-related doses may be significant and even exceed the professional limits if no precautions are taken. (P.A.)

  6. The 1D Richards' equation in two layered soils: a Filippov approach to treat discontinuities

    Science.gov (United States)

    Berardi, Marco; Difonzo, Fabio; Vurro, Michele; Lopez, Luciano

    2018-05-01

    The infiltration process into the soil is generally modeled by the Richards' partial differential equation (PDE). In this paper a new approach for modeling the infiltration process through the interface of two different soils is proposed, where the interface is seen as a discontinuity surface defined by suitable state variables. Thus, the original 1D Richards' PDE, enriched by a particular choice of the boundary conditions, is first approximated by means of a time semidiscretization, that is by means of the transversal method of lines (TMOL). In such a way a sequence of discontinuous initial value problems, described by a sequence of second order differential systems in the space variable, is derived. Then, Filippov theory on discontinuous dynamical systems may be applied in order to study the relevant dynamics of the problem. The numerical integration of the semidiscretized differential system will be performed by using a one-step method, which employs an event driven procedure to locate the discontinuity surface and to adequately change the vector field.

  7. MIT-Skywalker: Evaluating comfort of bicycle/saddle seat.

    Science.gov (United States)

    Goncalves, Rogerio S; Hamilton, Taya; Daher, Ali R; Hirai, Hiroaki; Krebs, Hermano I

    2017-07-01

    The MIT-Skywalker is a robotic device developed for the rehabilitation of gait and balance after a neurological injury. This device has been designed based on the concept of a passive walker and provides three distinct training modes: discrete movement, rhythmic movement, and balance training. In this paper, we present our efforts to evaluate the comfort of a bicycle/saddle seat design for the system's novel actuated body weight support device. We employed different bicycle and saddle seats and evaluated comfort using objective and subjective measures. Here we will summarize the results obtained from a study of fifteen healthy subjects and one stroke patient that led to the selection of a saddle seat design for the MIT-Skywalker.

  8. MIT LMFBR blanket research project. Final summary report

    International Nuclear Information System (INIS)

    Driscoll, M.J.

    1983-08-01

    This is a final summary report on an experimental and analytical program for the investigation of LMFBR blanket characteristics carried out at MIT in the period 1969 to 1983. During this span of time, work was carried out on a wide range of subtasks, ranging from neutronic and photonic measurements in mockups of blankets using the Blanket Test Facility at the MIT Research Reactor, to analytic/numerical investigations of blanket design and economics. The main function of this report is to serve as a resource document which will permit ready reference to the more detailed topical reports and theses issued over the years on the various aspects of project activities. In addition, one aspect of work completed during the final year of the project, on doubly-heterogeneous blanket configurations, is documented for the record

  9. Endokrinologische Behandlung der Geschlechtsdysphorie bei Menschen mit Geschlechtsinkongruenz

    Directory of Open Access Journals (Sweden)

    Flütsch N

    2015-01-01

    Full Text Available Es gibt Menschen, die die innere Gewissheit besitzen, dass ihre Geschlechtsidentität nicht zu ihrem biologischen Ursprungsgeschlecht passt. Durch die Entwicklungen in der Medizin in den letzten hundert Jahren ist es möglich geworden, die körperlichen Geschlechtsmerkmale an das innerlich erlebte Geschlecht anzupassen. Die Zahl der Hilfesuchenden in den ärztlichen Ambulanzen und Privatpraxen hat in den vergangenen Jahren deutlich zugenommen. Das Vorgehen bei der Diagnostik und Therapieeinleitung erlebt zurzeit eine deutliche Veränderung hin zu mehr Patientenzentriertheit und Individualisierung des Transitionsprozesses. Dabei bildet die geschlechtsangleichende Hormontherapie ein wesentliches Standbein in der körperlichen Angleichung an das Gegengeschlecht. Unter Beachtung von bestimmten Sicherheitsaspekten ist eine Hormontherapie mit Sexualhormonen sicher und einfach durchzuführen. Regelmäßige Verlaufskontrollen sowie der offene und affirmative Umgang mit den Betroffenen tragen zudem wesentlich zur Sicherheit in der Behandlung bei.

  10. Are the N and Δ deformed MIT bags

    International Nuclear Information System (INIS)

    Clement, G.; Maamache, M.

    1985-01-01

    The influence of the one-gluon exchange interaction, zero-point energy, and centre-of-mass correction, on the deformation of the nucleon and Δ bags, is studied in the MIT bag model. If the sharp MIT boundary conditions are taken seriously, the strong dependence of the zero-point energy on the deformation leads to the collapse of the N and Δ bags for realistic values of the strong fine structure constant α/sub S/. If on the other hand the zero-point energy is ignored altogether, then the nucleon, spherical for α/sub S/ 3.25, while the Δ is always prolate. The various predictions of the model are, for α/sub S/> or approx. =3.25, consistent with experiment, except for the proton magnetic moment which is only about 40% of the experimental value

  11. Properties of hybrid stars in an extended MIT bag model

    International Nuclear Information System (INIS)

    Bao Tmurbagan; Liu Guangzhou; Zhu Mingfeng

    2009-01-01

    The properties of hybrid stars are investigated in the framework of the relativistic mean field theory (RMFT) and an MIT bag model with density-dependent bag constant to describe the hadron phase (HP) and quark phase (QP), respectively. We find that the density-dependent B(ρ) decreases with baryon density ρ; this decrement makes the strange quark matter become more energetically favorable than ever; which makes the threshold densities of the hadron-quark phase transition lower than those of the original bag constant case. In this case, the hyperon degrees of freedom can not be considered. As a result, the equations of state of a star in the mixed phase (MP) become softer whereas those in the QP become stiffer, and the radii of the star obviously decrease. This indicates that the extended MIT bag model is more suitable to describe hybrid stars with small radii. (authors)

  12. Elektrochemisches Verhalten von Lithium-Schwefel-Zellen mit unterschiedlicher Kathodenstruktur

    OpenAIRE

    Scherr, Christopher

    2014-01-01

    Die elektrochemische Energiespeicherung ist in der Elektromobilität und dezentralen Energieversorgung einer der wichtigsten Bausteine. Der Lithium-Schwefel-Akkumulator mit seinen hohen theoretischen Kennwerte hat das Potential in Zukunft, hierbei eine gewichtige Rolle zu spielen. Je nach Zusammensetzung und Herstellung der Kathode variieren die Kennwerte jedoch sehr stark. In dieser Arbeit wurde der Einfluss der Kathodenstruktur und -zusammensetzung auf die Kapazität und Lebensdauer untersuch...

  13. Quark matter revisited with non-extensive MIT bag model

    Energy Technology Data Exchange (ETDEWEB)

    Cardoso, Pedro H.G.; Nunes da Silva, Tiago; Menezes, Debora P. [Universidade Federal de Santa Catarina, Departamento de Fisica, CFM, Florianopolis (Brazil); Deppman, Airton [Instituto de Fisica da Universidade de Sao Paulo, Sao Paulo (Brazil)

    2017-10-15

    In this work we revisit the MIT bag model to describe quark matter within both the usual Fermi-Dirac and the Tsallis statistics. We verify the effects of the non-additivity of the latter by analysing two different pictures: the first order phase transition of the QCD phase diagram and stellar matter properties. While the QCD phase diagram is visually affected by the Tsallis statistics, the resulting effects on quark star macroscopic properties are barely noticed. (orig.)

  14. Configuration management plan for Machine Interface Test System (MITS)

    International Nuclear Information System (INIS)

    O'Neill, C.K.

    1980-01-01

    The discipline required by this plan will apply from the establishment of a configuration baseline until completion of the final test in the MITS. The plan applies to configured items of hardware and software as well as to the specifications and drawings for these items. The plan encompasses establishment of the facility baseline, interface definition, classes of change, change control, change paper, organizational responsibilities and relationships, test configuration (as opposed to facility), and configuration data retention

  15. Optische Bildgebung der Autoimmunarthritis mit DiD markierten Leukozyten

    OpenAIRE

    Kau, Julia

    2008-01-01

    Zielsetzung: Ziel der vorliegenden Studie war es, zu untersuchen, ob die Optische Bildgebung nach Injektion von ex vivo DiD markierten Leukozyten, in der Lage ist, eine Entzündung der Synovialmembran in Ratten mit einer Antigen-induzierten Monoarthritis des rechten Kniegelenkes aufzudecken. Die Optische Bildgebung wurde auf ihre Fähigkeit zur Unterscheidung zwischen arthritischen und gesunden Kniegelenken und zwischen nichttherapierten und Kortison-therapierten Kniegelenken unt...

  16. Psychologie - Fachdatenbank mit europäischem Fokus

    OpenAIRE

    Schön, Dana

    2010-01-01

    Die Sichtbarkeit von europäischer Wissenschaftsliteratur ist notwendige Voraussetzung für deren Rezeption im internationalen Kontext. Ein bibliographisches Nachweissystem psychologischer Fachliteratur auf der Basis moderner Suchtechnologie mit Fokus auf europäischen Werken kann einen wichtigen Beitrag dazu leisten. Mehrere europäische Institute stellen ihre bibliographischen Datenbestände zum Aufbau einer umfassenden europäischen Fachdatenbank für die Psychologie zur Verfügung. Die Bereitstel...

  17. Qanti-QG hermaphrodite mesons in the MIT bag model

    International Nuclear Information System (INIS)

    Barnes, T.; Close, F.E.; Viron, F. de

    1982-10-01

    It is suggested that hermaphrodite (qanti-qg) mesons could exist with rather light masses. The spectrum of the ground state nonets, Jsup(PC) = (0, 1, 2) -+ ; 1 -- is calculated in the MIT bag model including 0(αsub(s)) energy shifts. Hadronic transitions among these states are discussed, considering their possible production at LEAR and SPEAR and indicating some interesting decay signatures. (author)

  18. Strategien zur HLA-Typisierung mit PyrosequencingTM

    OpenAIRE

    Entz, Patricia

    2006-01-01

    Der Haupthistokompatibilitätskomplex ist durch seine biologische Funktion eine für die Diagnostik und Forschung äußerst wichtige Region im humanen Genom. Die Untersuchung von HLA-Genorten stellt ein wichtiges Instrument in der molekulargenetischen Praxis dar. Die Pyrosequencing-Technik ist gut geeignet, um kurze DNA-Abschnitte mit weitgehend bekannter Sequenz schnell und effizient zu untersuchen. Ziel dieser Arbeit war die Entwicklung von Pyrosequencing-basierten Methoden zur HLA-Typisierung....

  19. Cost accounting in Kernforschungsanlage Juelich Gesellschaft mit beschraenkter Haftung (KFA)

    International Nuclear Information System (INIS)

    Seidel, G.; Schilling, H.

    1979-01-01

    The paper gives an overview about the organization and the research program of the Kernforschungsanalage Juelich Gesellschaft mit beschraenkter Haftung (KFA). The cost accounting system is discussed in detail, cost categories, cost centers, units of production and the data flow of the cost accounting are described. The distribution of the resulting management accounting reports and all sorts of EDP-result listings of the cost accounting system is described. (A.N.)

  20. Kundenorientierte Produktentwicklung mit Hilfe von Quality Function Deployment (QFD)

    OpenAIRE

    Schloske, Alexander

    2011-01-01

    Die Produktentwicklung von heute muss in immer kürzeren Zeiträumen kunden- und kostenorientierte Produkte entwickeln. Zur systematischen Unterstützung dieser Aufgabe im Rahmen der Produktentwicklung wird die Methode Quality Function Deployment (QFD) eingesetzt. Die konsequente Umsetzung der Stimme des Kunden in die Sprache des Unternehmens gelingt mit Quality Function Deployment (QFD). Die Methode wertet systematisch Kundenanforderungen an Produkte aus und führt zu innovativen Lösungen, die s...

  1. Phylogenetic relationships of the Gomphales based on nuc-25S-rDNA, mit-12S-rDNA, and mit-atp6-DNA combined sequences

    Science.gov (United States)

    Admir J. Giachini; Kentaro Hosaka; Eduardo Nouhra; Joseph Spatafora; James M. Trappe

    2010-01-01

    Phylogenetic relationships among Geastrales, Gomphales, Hysterangiales, and Phallales were estimated via combined sequences: nuclear large subunit ribosomal DNA (nuc-25S-rDNA), mitochondrial small subunit ribosomal DNA (mit-12S-rDNA), and mitochondrial atp6 DNA (mit-atp6-DNA). Eighty-one taxa comprising 19 genera and 58 species...

  2. Nagelbefall kann bei Patienten mit Psoriasis auf eine Enthesiopathie hinweisen.

    Science.gov (United States)

    Castellanos-González, Maria; Joven, Beatriz Esther; Sánchez, Julio; Andrés-Esteban, Eva María; Vanaclocha-Sebastián, Francisco; Romero, Pablo Ortiz; Díaz, Raquel Rivera

    2016-11-01

    Obwohl subklinische Enthesiopathie ein gut etabliertes diagnostisches Merkmal der Psoriasisarthritis (PsA) ist, wird sie häufig übersehen, da viele Patienten asymptomatisch sind. Gäbe es klinische Hinweise auf das Vorliegen einer Enthesiopathie, würde dies den Klinikern die Möglichkeit eröffnen, eine PsA frühzeitig zu diagnostizieren. Es wurde eine monozentrische prospektive Studie mit insgesamt 90 Psoriasis-Patienten durchgeführt, um mittels Ultraschall das Vorliegen von Enthesenanomalien zu untersuchen und eine Korrelation mit dem Befall der Nägel festzustellen. Enthesenanomalien wurden bei 23 Patienten (25,5 %) gefunden, von denen 19 (82,6 %) Nagelbefall aufwiesen. Bei 4 Patienten waren die Nägel nicht betroffen. Enthesiopathie lag bei 31,1 % (19/61) der Patienten mit Onychopathie vor, von den Patienten ohne Nagelbefall litten nur 13,8 % (4/29) an Enthesiopathie (p = 0,07). Zwischen dem Target-NAPSI-Score und dem Vorliegen einer Enthesiopathie bestand eine signifikante Korrelation. Eine signifikante Korrelation bestand darüber hinaus auch zwischen dem Vorliegen einer Enthesiopathie und der Anzahl der betroffenen Nägel (p = 0,035). Klinische Belege für eine Onychopathie können der Schlüssel für die frühe Diagnose einer Enthesiopathie bei Psoriasis-Patienten sein. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  3. Quantum mechanics in the cold war; Quantenmechanik im Kalten Krieg. David Bohm und Richard Feynman

    Energy Technology Data Exchange (ETDEWEB)

    Forstner, C.

    2007-07-01

    In the middle of the 20th century David Bohm and Richard Feynman developed two fundamentally different approaches of modern quantum mechanics: Bohm a realistic interpretation by means of hidden parameters and Feynman the path-integral formalism. This is by this more remarakable, because both physicists started from similar conditions and originated from similar connections. By its comparing approach this study presents more than a contribution to the history of the quantum theory. By the question for the social and cultural conditions of the formation of theories it is furthermore of science-sociological and science-theoretical interest. The in the beginning similar and later different binding of both scientists into the scientific community allows furthermore to study, which adapting pressure each group puts on the individual scientist and the fundamental parts of his research, and which new degrees of freedom in the formation of theories arise, when this constraint is cancelled.

  4. Richard Arwed Pfeifer - a pioneer of 'medical pedagogy' and an opponent of Paul Schroder.

    Science.gov (United States)

    Steinberg, Holger; Carius, Dirk; Himmerich, Hubertus

    2013-12-01

    Richard Arwed Pfeifer (1877-1957) was one of the initiators and foster fathers of the renowned child-psychiatric and special needs education workgroup at Leipzig University under Paul Schröder (1873-1941) in the 1920s and 1930s. This paper is an account of their dispute concerning the interrelations between child and adolescent psychiatry and special needs education, as well as their disagreement about whether adolescent psychopaths should be admitted to specialized child psychiatric wards or elsewhere. Moreover, Pfeifer questioned the practical relevance of the separation of constitutional and environmentally-based psychopathy and fought eugenic research, which he found incompatible with the ethics of his profession as a remedial teacher and child psychiatrist.

  5. Destruction of the Phoenix/Hibiscus and Barringtonia racemosa Communities at Richards Bay, Natal, South Africa

    Directory of Open Access Journals (Sweden)

    P. J. Weisser

    1982-10-01

    Full Text Available The destruction of the Phoenix!Hibiscus and Barringtonia racemosa Communities described by Venter in 1972 on the southern shores of Richards Bay is reported. The cause was the artificial openingof a new mouth about 5,5 km south of the original mouth, which increased tidal range and salinity. These swamp communities occupied a narrow band about 6 ha in area behind the Bruguiera gymnorrhiza Community. An estimated 95 % of the communities was affected and only on the landward border were some isolated remnants of species such as Acrostichum aureum, Hibiscus tiliaceus and Phoenix reclinata detected .Young stands of  Phragmites australis, seedlings of  Bruguiera gymnorrhiza and Avicennia marina and epipelic algae are recoIonizing the affected area.

  6. Marie-Christine Agosto. Richard Brautigan. Les fleurs de néant.

    Directory of Open Access Journals (Sweden)

    Jean-Bernard Basse

    2006-04-01

    Full Text Available Richard Brautigan, si on lui reconnaît un certain humour, est souvent associé avec condescendance au phénomène hippy et considéré comme un auteur démodé, superficiel. Celui qui écrivait dans Cahier d’un Retour de Troie : « Les mots sont des fleurs de néant » est pourtant l’un de ces écrivains que l’on pourrait qualifier de mineurs essentiels, et seuls ceux qui l’ont peu ou mal lu s’étonneront de ce que Marie-Christine Agosto ait choisi de donner comme sous-titre « Les fleurs de néant » au pet...

  7. Harmonic analysis, partial differential equations and applications in honor of Richard L. Wheeden

    CERN Document Server

    Franchi, Bruno; Lu, Guozhen; Perez, Carlos; Sawyer, Eric

    2017-01-01

    This is a collection of contributed papers by many eminent Harmonic Analysts and specialists of Partial Differential equations. The papers focus on weighted norm equalities for singular integrals, focusing wave equations, degenerate elliptic equations, Navier-Stokes flow in two dimensions and Poincare-Sobolev inequalities in the setting of metric spaces equipped with measures among others. Many topics considered in this volume stem from the interests of Richard L. Wheeden whose contributions to Potential Theory, singular integral theory and degenerate elliptic PDE theory this volume honors. Luis Caffarelli, Sagun Chanillo, Bruno Franchi, Cristian Guttierez, Xiaojun Huang, Carlos Kenig, Ermanno Lanconelli, Eric Sawyer and Alexander Volberg, are some of the many contributors to this volume. .

  8. A critical review of Richard Lynn's reports on reaction time and race.

    Science.gov (United States)

    Thomas, Drew M

    2011-01-01

    In the early 1990s, psychologist Richard Lynn published papers documenting average reaction times and decision times in samples of nine-year-olds taken from across the world. After summarizing these data, Lynn interpreted his results as evidence of national and racial differences in decision time and general intelligence. Others have also interpreted Lynn's data as evidence of racial differences in decision time and intelligence. However, comparing Lynn's summaries with his original reports shows that Lynn misreported and omitted some of his own data. Once these errors are fixed the rankings of nations in Lynn's datasets are unstable across different decision time measures. This instability, as well as within-race heterogeneity and between-race overlap in decision times, implies that Lynn's reaction time data do not permit generalizations about the decision times and intelligence of people of different races.

  9. Analytical and grid-free solutions to the Lighthill-Whitham-Richards traffic flow model

    KAUST Repository

    Mazaré , Pierre Emmanuel; Dehwah, Ahmad H.; Claudel, Christian G.; Bayen, Alexandre M.

    2011-01-01

    In this article, we propose a computational method for solving the Lighthill-Whitham-Richards (LWR) partial differential equation (PDE) semi-analytically for arbitrary piecewise-constant initial and boundary conditions, and for arbitrary concave fundamental diagrams. With these assumptions, we show that the solution to the LWR PDE at any location and time can be computed exactly and semi-analytically for a very low computational cost using the cumulative number of vehicles formulation of the problem. We implement the proposed computational method on a representative traffic flow scenario to illustrate the exactness of the analytical solution. We also show that the proposed scheme can handle more complex scenarios including traffic lights or moving bottlenecks. The computational cost of the method is very favorable, and is compared with existing algorithms. A toolbox implementation available for public download is briefly described, and posted at http://traffic.berkeley.edu/project/downloads/lwrsolver. © 2011 Elsevier Ltd.

  10. Richard Wrangham. Catching fire. How cooking made us Human. Basic Books (Perseus Books Group

    Directory of Open Access Journals (Sweden)

    Claude-Marcel Hladik

    2009-11-01

    Full Text Available L’histoire de l’émergence de l’homme est remise en cause par cet ouvrage puisque jusqu’à présent la plupart des anthropologues et des paléontologues s’accordaient pour faire remonter à environ 500.000 ans les premières utilisations du feu pour la cuisson des aliments par le genre Homo. Les arguments présentés par Richard Wrangham dans son dernier ouvrage nous font remonter aux deux derniers millions d’années. Wrangham et ses collègues avaient publié, dès 1999, les résultats de fouilles au cou...

  11. Analytical and grid-free solutions to the Lighthill-Whitham-Richards traffic flow model

    KAUST Repository

    Mazaré, Pierre Emmanuel

    2011-12-01

    In this article, we propose a computational method for solving the Lighthill-Whitham-Richards (LWR) partial differential equation (PDE) semi-analytically for arbitrary piecewise-constant initial and boundary conditions, and for arbitrary concave fundamental diagrams. With these assumptions, we show that the solution to the LWR PDE at any location and time can be computed exactly and semi-analytically for a very low computational cost using the cumulative number of vehicles formulation of the problem. We implement the proposed computational method on a representative traffic flow scenario to illustrate the exactness of the analytical solution. We also show that the proposed scheme can handle more complex scenarios including traffic lights or moving bottlenecks. The computational cost of the method is very favorable, and is compared with existing algorithms. A toolbox implementation available for public download is briefly described, and posted at http://traffic.berkeley.edu/project/downloads/lwrsolver. © 2011 Elsevier Ltd.

  12. Book review: Unholy trinity: The IMF, World Bank and WTO Richard Peet

    Directory of Open Access Journals (Sweden)

    M Breitenbach

    2014-05-01

    Full Text Available In this timely book Richard Peet and his team lay the foundation with an excellent analysis of the process of globalisation and the resultant emergence of the global economy. The authors are especially critical of the increasing influence of institutions like the International Monetary Fund (IMF, World Bank and World Trade Organisation (WTO on the economy and the consequences experienced by peoples, cultures and the environment. The single ideology of neo-liberalism is blamed for the undesirable outcomes. This book considers concepts of power, political interest, hegemony, discourse, responsibility and the power of practicality, in critically examining the IMF, World Bank and WTO. The conclusion is reached that “all three institutions play roles greatly different from those originally agreed to under the charters that set them up”.

  13. Femineidad y ficción en la obra operística de Richard Strauss

    Directory of Open Access Journals (Sweden)

    María José Sánchez Usón

    2014-01-01

    Full Text Available Tras la muerte de Wagner y Brahms, Richard Straussemergió como uno de los compositores más importantesy populares de la música del siglo XX. Su trayectoria vitaly profesional, azarosa y turbulenta, al igual que las décadasque vivió, estuvo marcada por la realidad femenina.Es innegable que las mujeres de la vida de Strauss, todasde fuerte y distintiva personalidad, dejaron en él huellastan hondas que fue necesario llevarlas a escena, no sólocomo una aportación valiosa a la tipología caracterológicafemenina, sino también como un ejercicio terapéuticopersonal. Así, mujeres reales y mujeres ficticias se confundenen sus obras en un proceso creativo único: el delhombre-artista.

  14. BACK TO THE ORIGINS OF THE REPUDIATION OF WUNDT: OSWALD KÜLPE AND RICHARD AVENARIUS.

    Science.gov (United States)

    Russo Krauss, Chiara

    2017-01-01

    This essay provides a fresh account of the break between Oswald Külpe and his master Wilhelm Wundt. Kurt Danziger's reconstruction of the "repudiation" of Wundt, which has become the canon for this significant episode of history of psychology, focused on the supposed influence of Ernst Mach on this set of events, overshadowing the other exponent of Empiriocriticism: Richard Avenarius. Analyzing archival documents and examining anew the primary sources, the paper shows that Avenarius was himself a member of Wundt's circle, and that his "repudiation" of the master paved the way for Külpe. The essay points out the original anti-Wundtian aspects of Avenarius' notion of psychology, thus showing how they were then adopted by Külpe. © 2016 Wiley Periodicals, Inc.

  15. Lucien Cuénot, Richard Goldschmidt y Miquel Crusafont Pairó

    Directory of Open Access Journals (Sweden)

    Casinos, Adrià

    2016-06-01

    Full Text Available An unpublished text, corresponding to a communication done by Crusafont Pairó is analysed. The communication is strongly critical with Cuénot’s necrology published previously by Goldschmidt, where he regrets the teleological ideas on evolution that Cuénot maintained in the last years of his life.Se analiza un texto inédito de Miquel Crusafont Pairó, correspondiente a comunicación que llevó a cabo en la Fundació Bosch i Cardellach, sobre la necrológica de Lucien Cuénot publicada por Richard Goldschmidt. La comunicación es un fuerte ataque a Goldschmidt por sus críticas a la deriva teleológica de Cuénot en los últimos años de su vida.

  16. Nothing Risked, Nothing Gained: Richard Powers' Gain and the Horizon of Risk

    Directory of Open Access Journals (Sweden)

    Aaron Jaffe

    2010-02-01

    Full Text Available Cet article interprète Gain, sixième roman de Richard Powers, à la lumière du concept de « seconde modernité » proposé par le sociologue allemand Ulrich Beck. Ce concept souligne la dissémination du risque et la manière dont celle-ci invalide les marchés conclus par la « première modernité » entre l’avenir et le présent, entre l’intérieur du corps et l’extérieur. Cet article entend montrer que Beck fournit un cadre interprétatif utile à la compréhension de ces rapports, hors des impasses catégorielles que suscite l’opposition entre les deux régimes narratifs à l’œuvre dans le texte : le récit biographique, local et individuel, de la maladie de Laura Rowen Bodey, et l’histoire collective de l’entreprise Clare devenue conglomérat.This essay interprets Richard Powers' sixth novel Gain with reference to the German sociologist Ulrich Beck's concept of “second modernity.” The concept underscores the dispersal of risk and how it shreds promissory notes understood in “first modernity” between the future and present and the insides and outsides of the body. It argues that Beck supplies an apt interpretive framework for understanding these relationships and overcoming the categorical impasses between the two narrative words at work in Power's novel, the biographical situatedness of Laura Rowen Bodey's illness and the corporate history of the Clare conglomerate.

  17. Newtonian nudging for a Richards equation-based distributed hydrological model

    Science.gov (United States)

    Paniconi, Claudio; Marrocu, Marino; Putti, Mario; Verbunt, Mark

    The objective of data assimilation is to provide physically consistent estimates of spatially distributed environmental variables. In this study a relatively simple data assimilation method has been implemented in a relatively complex hydrological model. The data assimilation technique is Newtonian relaxation or nudging, in which model variables are driven towards observations by a forcing term added to the model equations. The forcing term is proportional to the difference between simulation and observation (relaxation component) and contains four-dimensional weighting functions that can incorporate prior knowledge about the spatial and temporal variability and characteristic scales of the state variable(s) being assimilated. The numerical model couples a three-dimensional finite element Richards equation solver for variably saturated porous media and a finite difference diffusion wave approximation based on digital elevation data for surface water dynamics. We describe the implementation of the data assimilation algorithm for the coupled model and report on the numerical and hydrological performance of the resulting assimilation scheme. Nudging is shown to be successful in improving the hydrological simulation results, and it introduces little computational cost, in terms of CPU and other numerical aspects of the model's behavior, in some cases even improving numerical performance compared to model runs without nudging. We also examine the sensitivity of the model to nudging term parameters including the spatio-temporal influence coefficients in the weighting functions. Overall the nudging algorithm is quite flexible, for instance in dealing with concurrent observation datasets, gridded or scattered data, and different state variables, and the implementation presented here can be readily extended to any of these features not already incorporated. Moreover the nudging code and tests can serve as a basis for implementation of more sophisticated data assimilation

  18. Physikalische Grundlagen von chemischen Raman-Sensoren mit Schwerpunkt auf faseroptischen SERS-Sonden

    OpenAIRE

    Viets, Carmen

    2001-01-01

    Faseroptische SERS-Sensoren wurden durch die Beschichtung der Endflächen von optischen Fasern mit rauhen Metallfilmen erzeugt. Zu den verschiedenen Präparationstechniken, die angewendet und verglichen wurden, gehörten das langsame Aufdampfen von Metall-Inselfilmen und das Bedampfen von Nanopartikeln, aufgerauhten oder elektronenlithographisch strukturierten Oberflächen mit Metallfilmen. Der Einfluß der Laserleistung auf die Messungen mit SERS-Sensoren wurde untersucht, und es wurden maximale ...

  19. Quantitative Datenanalyse: Arbeiten mit SPSS Statistics : Eine Einführung

    OpenAIRE

    Hoidn, Sabine

    2012-01-01

    Bei diesem Buch handelt es sich um eine verständliche Einführung in das Arbeiten mit dem quantitativen Datenanalyseprogramm SPSS Statistics. Die Studierenden setzen sich mit den Grundlagen zum Arbeiten mit SPSS Statistics auseinander, können selbständig eine SPSS Statistics-Datei erstellen, Daten einlesen, zusammenfügen und modifizieren, erfasste Daten managen und die gebräuchlichsten tabellarischen und grafischen Grundauswertungen sowie Analyseverfahren durchführen und interpretieren. Au...

  20. The development of form two mathematics i-Think module (Mi-T2)

    Science.gov (United States)

    Yao, Foo Jing; Abdullah, Mohd Faizal Nizam Lee; Tien, Lee Tien

    2017-05-01

    This study aims to develop a training module i-THINK Mathematics Form Two (Mi-T2) to increase the higher-order thinking skills of students. The Mi-T2 training module was built based on the Sidek Module Development Model (2001). Constructivist learning theory, cognitive learning theory, i-THINK map and higher order thinking skills were the building blocks of the module development. In this study, researcher determined the validity and reliability of Mi-T2 module. The design being used in this study was descriptive study. To determine the needs of Mi-T2 module, questionnaires and literature review were used to collect data. When the need of the module was determined, the module was built and a pilot study was conducted to test the reliability of the Mi-T2 module. The pilot study was conducted at a secondary school in North Kinta, Perak. A Form Two class was selected to be the sample study through clustered random sampling. The pilot study was conducted for two months and one topic had been studied. The Mi-T2 module was evaluated by five expert panels to determine the content validity of the module. The instruments being used in the study were questionnaires about the necessity of the Mi-T2 module for guidance, questionnaires about the validity of the module and questionnaires concerning the reliability of the module. Statistical analysis was conducted to determine the validity and reliability coefficients of the Mi-T2 module. The content validity of Mi-T2 module was determined by Cohen's Kappa's (1968) agreement coefficient and the reliability of Mi-T2 module was determined by Cronbach Alpha's value scale. The content validity of Mi-T2 module was 0.89 and the Cronbach Alpha's value of Mi-T2 module was 0.911.

  1. Der Ritter mit dem Hemd : drei Fassungen einer mittelalterlichen Erzählung

    OpenAIRE

    Dunphy, Graeme

    2011-01-01

    Unter den zahlreichen Motiven, die in der mittelalterlichen Literatur mit Frauendienst verbunden sind, gehört das vom Ritter mit dem Hemd zu den besonders interessanten. Es erscheint zunächst in dem ersten von fünf Fabliaux aus einer verlorenen Turiner Handschrift, die dem sonst unbekannten altfranzösischen Dichter Jacques de Baisieux zugeschrieben werden, einer heiteren Kurzgeschichte mit dem Titel "Des trois chevaliers et del chainse". In der vorliegenden Untersuchung gilt es, der Frage der...

  2. Kitchenette: Hell or Home? Different"Kitchenette"Images Created by Richard Wright and Gwendolyn Brooks%Kitchenette:Hell or Home?Different"Kitchenette"Images Created by Richard Wright and Gwendolyn Brooks

    Institute of Scientific and Technical Information of China (English)

    肖志宏

    2017-01-01

    How the southern black migrants navigate and survive the northern urban space is a question profoundly explored and realistically documented in many migration narratives in African American literature. This paper concentrates on the image of Chicago"kitchenette"in the works of Richard Wright and Gwendolyn Brooks, in an attempt to demonstrate the different inter-pretations of migrant spaces on the urban landscape.

  3. Wirksamkeit und Sicherheit von Fumarsäureestern in Kombination mit Phototherapie bei Patienten mit moderater bis schwerer Plaque-Psoriasis (FAST).

    Science.gov (United States)

    Weisenseel, Peter; Reich, Kristian; Griemberg, Wiebke; Merten, Katharina; Gröschel, Christine; Gomez, Natalie Nunez; Taipale, Kirsi; Bräu, Beate; Zschocke, Ina

    2017-02-01

    Die Behandlung von Psoriasis-Patienten mit einer Kombination aus Fumarsäureestern (FSE, Fumaderm ® ) und Phototherapie (UV) ist verbreitet, wurde aber im Rahmen von Studien wenig untersucht. Bisher liegen lediglich Daten aus einer kleinen Pilotstudie vor. Intention dieser Studie war, eine FSE/UV-Kombinationsbehandlung an einem größeren Patientenkollektiv mit mittelschwerer bis schwerer Psoriasis zu untersuchen. In dieser prospektiven, multizentrischen, nichtinterventionellen Studie wurden Daten von Patienten mit FSE/UV-Kombinationstherapie hinsichtlich der Wirksamkeit (PGA' PASI, DLQI, EQ-5D), Sicherheit und Dosierung über einen Zeitraum von zwölf Monaten erfasst und mit Daten einer retrospektiven Studie mit FSE-Monotherapie verglichen. Es wurden Daten von 363 Patienten ausgewertet. Unter der Kombinationstherapie verbesserten sich alle Wirksamkeitsparameter deutlich. Im Vergleich zur Monotherapie mit FSE konnte durch die Kombination mit UV ein schnellerer Wirkeintritt erzielt werden, wobei nach zwölf Monaten kein Unterschied in der Wirksamkeit bestand. Die Dauer und Art der Phototherapie zeigte keinen Einfluss auf die Wirksamkeitsparameter. Allgemein wurde die Kombinationstherapie gut vertragen. Unerwünschte Ereignisse wurden bei 7 % der Patienten berichtet. Die FSE/UV Kombinationstherapie zeigt eine gute Wirksamkeit und Verträglichkeit und kann zu einem schnelleren Wirkeintritt führen. Eine Kombinationstherapie erscheint vor allem in den ersten drei Monaten der FSE Behandlung sinnvoll. © 2017 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  4. Kompressionstherapie - Versorgungspraxis: Informationsstand von Patienten mit Ulcus cruris venosum.

    Science.gov (United States)

    Protz, Kerstin; Heyer, Kristina; Dissemond, Joachim; Temme, Barbara; Münter, Karl-Christian; Verheyen-Cronau, Ida; Klose, Katharina; Hampel-Kalthoff, Carsten; Augustin, Matthias

    2016-12-01

    Eine Säule der kausalen Therapie bei Patienten mit Ulcus cruris venosum ist die Kompressionstherapie. Sie unterstützt die Abheilung, reduziert Schmerzen und Rezidive und steigert die Lebensqualität. Bislang existieren kaum wissenschaftliche Daten zu dem Versorgungsstand und fachspezifischem Wissen von Patienten mit Ulcus cruris venosum. Standardisierte Fragebögen wurden bundesweit in 55 Pflegediensten, 32 Arztpraxen, vier Wundzentren und -sprechstunden sowie einem Pflegetherapiestützpunkt von Patienten mit Ulcus cruris venosum bei Erstvorstellung anonym ausgefüllt. Insgesamt nahmen 177 Patienten (Durchschnittsalter 69,4 Jahre; 75,1 % Frauen) teil. Ein florides Ulcus cruris venosum bestand im Mittel 17 Monate. 31,1 % hatten keine Kompressionstherapie, 40,1 % Binden und 28,8 % Strümpfe. Bei der Bestrumpfung hatten 13,7 % Kompressionsklasse III, 64,7 % Kompressionsklasse II und 19,6 % Kompressionsklasse I. 70,6 % legten die Strümpfe nach dem Aufstehen an, 21,1 % trugen sie Tag und Nacht. 39,2 % bereiteten die Strümpfe Beschwerden. Lediglich 11,7 % hatten eine An- und Ausziehhilfe. Die Binden wurden im Mittel 40,7 Wochen getragen und bei 69 % nicht unterpolstert. Bei 2,8 % wurde der Knöchel- und Waden-Umfang zur Erfolgskontrolle gemessen. Venensport machten 45,9 %. Ein Drittel hatte keine Kompressionsversorgung, obwohl diese eine Basismaßnahme der Therapie des Ulcus cruris venosum ist. Zudem ist deren korrekte Auswahl und Anwendung angesichts der langen Bestandsdauer der Ulzerationen zu hinterfragen. Weiterführende Fachkenntnisse bei Anwendern und Verordnern sowie Patientenschulungen sind erforderlich. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  5. Comments on the MIT Assessment of the Mars One Plan

    Science.gov (United States)

    Jones, Harry W.

    2015-01-01

    The MIT assessment of the Mars One mission plan reveals design assumptions that would cause significant difficulties. Growing crops in the crew chamber produces excessive oxygen levels. The assumed in-situ resource utilization (ISRU) equipment has too low a Technology Readiness Level (TRL). The required spare parts cause a large and increasing launch mass logistics burden. The assumed International Space Station (ISS) Environmental Control and Life Support (ECLS) technologies were developed for microgravity and therefore are not suitable for Mars gravity. Growing food requires more mass than sending food from Earth. The large number of spares is due to the relatively low reliability of ECLS and the low TRL of ISRU. The Mars One habitat design is similar to past concepts but does not incorporate current knowledge. The MIT architecture analysis tool for long-term settlements on the Martian surface includes an ECLS system simulation, an ISRU sizing model, and an analysis of required spares. The MIT tool showed the need for separate crop and crew chambers, the large spare parts logistics, that crops require more mass than Earth food, and that more spares are needed if reliability is lower. That ISRU has low TRL and ISS ECLS was designed for microgravity are well known. Interestingly, the results produced by the architecture analysis tool - separate crop chamber, large spares mass, large crop chamber mass, and low reliability requiring more spares - were also well known. A common approach to ECLS architecture analysis is to build a complex model that is intended to be all-inclusive and is hoped will help solve all design problems. Such models can struggle to replicate obvious and well-known results and are often unable to answer unanticipated new questions. A better approach would be to survey the literature for background knowledge and then directly analyze the important problems.

  6. Richard J. Hill, Picturing Scotland through the Waverley Novels: Walter Scott and the Origins of the Victorian Illustrated Novel.

    Directory of Open Access Journals (Sweden)

    Jacqueline Irene Cannata

    2012-10-01

    Full Text Available Richard J. Hill, Picturing Scotland through the Waverley Novels: Walter Scott and the Origins of the Victorian Illustrated Novel . Farnham, Surrey, and Burlington, VT: Ashgate, 2010. Pp. 236. ISBN 978-0-7546-6806-0. US$99.99.

  7. Dr. Richard J. Whelan: Seeing the Field of Emotional and Behavior Disorders through the Lens of a Pioneer

    Science.gov (United States)

    Kaff, Marilyn S.; Teagarden, Jim; Zabel, Robert H.

    2011-01-01

    Dr. Richard J. Whelan is a distinguished professor emeritus at the University of Kansas. His earliest professional experiences were at the Children's Hospital (Southard School) of the Menninger Clinic, where he served as a recreational therapist, teacher, and director of education. During his career at the University of Kansas and the KU Medical…

  8. A soil moisture accounting-procedure with a Richards' equation-based soil texture-dependent parameterization

    Science.gov (United States)

    Given a time series of potential evapotranspiration and rainfall data, there are at least two approaches for estimating vertical percolation rates. One approach involves solving Richards' equation (RE) with a plant uptake model. An alternative approach involves applying a simple soil moisture accoun...

  9. Richards Bay Mesometeorological Data – Vertical profiles of air temperature and wind velocity and surface wind statistics.

    CSIR Research Space (South Africa)

    Scholtz, MT

    1978-03-01

    Full Text Available This report details the experimental methods and data obtained in the course of a study of the movement of stable air over a complex region. The field work was carried out in the Richards Bay area on the Natal Coast during the period May to August...

  10. Muusikamaailm : Suur klaveripidu Ruhrimaal. Kissingeni festival tippudega. Sulasoli 80. aastapäev. Richard Rodgers 100 / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2002-01-01

    6. juuni-17. augustini Ruhrimaal toimuvast klaverifestivalist. Bad Kissingenis toimuvatest suvepidustustest. Soome Lauljate ja Mängijate Liit tähistab asutamise 80. aastapäeva. Helilooja Richard Rodgersi sünnist möödub 100 aastat

  11. Elastolysen und Hauterkrankungen mit Verlust der elastischen Fasern.

    Science.gov (United States)

    Tronnier, Michael

    2018-02-01

    Die elastischen Fasern sind neben den kollagenen Fasern der wichtigste Bestandteil des Bindegewebsgerüstes der Haut. Eine Verminderung oder ein Verlust der elastischen Fasern ist bei einer Vielzahl von klinisch sich unterschiedlich präsentierenden Erkrankungen, hereditär oder erworben, beschrieben. Bei den Erkrankungen, die mit einer Entzündung einhergehen ist die Elastophagozytose ein wichtiges histologisches Merkmal. Die Therapie der Erkrankungen dieser Gruppe ist grundsätzlich schwierig. © 2018 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  12. Innovative facades with photovoltaics; Innovative Fassaden mit Photovoltaik

    Energy Technology Data Exchange (ETDEWEB)

    Eicker, U. [Hochschule fuer Technik, Stuttgart (Germany)

    1999-10-01

    Having grown at a rate of 15% since the middle of the 1980s the photovoltaic market today commands an annual module production of more than 100 MW{sub p}. In Germany altogether 10,000 PV systems with a total power output of 10 MW{sub p} were newly installed in 1997 alone. In 1990 the market was boosted by the heavily subsidised 1000 roofs programme, under which in the end more than 2,000 systems were installed on the roofs of mostly one-family houses. With power ratings ranging from 1 to 5 kW these decentral plants require roof surface areas between 10 and 50 m-2. On average they generate 800 kWh of electricity per kW of installed power. According to a number of studies carried out in the early 1990s the total surface area on buildings available for photovoltaics amounts to an enormous potential of 1,000 km-2, which is equivalent to an electricity generating potential of 130 TWh (100 TWh on roofs and 30 TWh on facades), or 25% of Germany`s total electricity demand. The degree to which this potential will be realised in the long term will notably depend on whether convincing architectural solutions are found for integrating photovoltaic plants in roofs and facades. [Deutsch] Der Photovoltaikmarkt waechst weltweit seit Mitte der 80er Jahre um durchschnittlich 15% und liegt heute bei einer Jahresmodulproduktion ueber 100 MW{sub p}. In Deutschland wurden alleine 1997 etwa 10.000 PV-Systeme mit einer Gesamtleistung von 10 MW{sub p} installiert. Die Marktentwicklung wurde 1990 mit dem stark subventionierten 1000-Daecher Programm angestossen, in welchem schliesslich mehr als 2000 Systeme meist auf Daechern von Einfamilienhaeusern installiert wurden. Diese dezentralen Anlagen mit Leistungen zwischen 1 und 5 kW erfordern Dachflaechen zwischen 10 und 50 m{sup 2} und erzeugen im Schnitt 800 kWh Strom pro kW installierter Leistung. Das verfuegbare Flaechenpotential von Gebaeuden wurde Anfang der 90er Jahre in einer Reihe von Studien ermittelt und stellt mit etwa 1000 km{sup 2

  13. Die Behandlung des Akustikusneurinoms mit dem Gamma-Knife

    OpenAIRE

    Hempel, Elizabeta

    2005-01-01

    Das Akustikusneurinom ist mit ca. 6% der häufigste intrakranielle Tumor und hat eine jährliche Inzidenz von 1:100000. Die durchschnittliche Wachstumsrate beträgt 2 mm pro Jahr, wobei es auch Akustikusneurinome gibt, die sehr viel schneller wachsen können. Bei der Behandlung des Schwannoms stehen uns zwei Modalitäten zur Verfügung. Die konventionelle Chirurgie und die stereotaktische Radiochirurgie, zu der die Gamma-Knife Therapie und der Linearbeschleuniger zählen. Sorgfältig ausgesuchte P...

  14. Content Management von Leittexten mit XML Topic Maps

    Directory of Open Access Journals (Sweden)

    Johannes Busse

    2003-07-01

    Full Text Available Die Autoren definieren den Umgang mit internet- basierten Informations- und Kommunikationstechnologien als Schlüsselqualifikation für Studierende aller Fachrichtungen. Im vorliegenden Aufsatz beschreiben sie ein Projekt, das der Fachbereich Erziehungswissenschaften der Universität Heidelberg seit 2001 durchführt. Hier werden Studierende der Geistes- und Sozialwissenschaften zu "Lernberatern" ausgebildet, die als Multiplikatoren die notwendigen Kenntnisse erwerben. Die Teilnehmenden erarbeiten nach der "Leittextmethode" selbstgesteuert xml-basierte Contents. Dies setzt den Erwerb von informationstechnischen Kenntnissen voraus, der neben dem Aufbau eines (sowohl technischen als auch sozialen Netzwerks einen Schwerpunkt bildet.

  15. Automatic control and monitoring of the MIT fission converter beam

    International Nuclear Information System (INIS)

    Wilson, B.A.; Riley, K.J.; Harling, O.K.

    2000-01-01

    An automated control and monitoring system for the new MIT high intensity epithermal neutron irradiation facility has been designed and constructed. The neutron beam is monitored with fission counters located at the periphery of the beam near the patient position. Control of the beam is accomplished with redundant Programmable Logic Controllers (PLCs). These industrial controllers open and close the three shutters of the Fission Converter Beam. The control system uses a series of robust components to assure that the prescribed fluence is delivered. This paper discusses the design and implementation of this system. (author)

  16. M1-transitions in the MIT bag model

    International Nuclear Information System (INIS)

    Hackman, R.H.; Deshpande, N.G.; Dicus, D.A.; Teplitz, V.L.

    1977-03-01

    In the MIT bag model, the M1-transitions of low lying hadrons are investigated. The following calculations are performed: 32 hadron masses are recomputed with a choice of bag parameters designed to give the correct values for the proton magnetic moment, μ/sub p/, and several masses, M/sub rho/ M/sub ω/ M/sub Δ/ M/sub Ω/, and M/sub D/; (2) eta, eta', eta/sub c/ mixing is computed in an untrustworthy approximation; and the widths for 38 M1-transitions are computed

  17. Recent work at MIT on uranium recovery from seawater

    International Nuclear Information System (INIS)

    Driscoll, M.J.

    1984-01-01

    Recent work at MIT has confirmed the superiority of fiber-form ion exchange media for uranium recovery from seawater, subject to demonstration of the ability to control fouling by suspended particulate matter. Calculations and laboratory experiments indicate loading rates of several hundred ppm U/day: an order of magnitude faster than for bead-type sorbers in fixed or fluidized beds. A high performance, modular, sorber cartridge/seawater contactor system capable of a lifetime-levelized cost of product in the range 100-150 $/1b U 3 O 8 has been designed. (author)

  18. Efficacy Quotient Tindakan ESWL Piezolith Richard Wolf 3000 pada Penderita Batu Ureter di RSUPN Dr. Cipto Mangunkusumo, 2008–2011

    Directory of Open Access Journals (Sweden)

    Vinny Verdini

    2017-01-01

    Full Text Available Extracorporeal shockwave lithotripsy (ESWL saat ini telah menjadi metode yang paling umum dalam tatalaksana aktif batu ureter. Sejak Maret 2008, RSCM telah menggunakan mesin ESWL piezolith 3000 richard wolf dan belum diketahui nilai efficacy quotient (EQ. Penelitian ini bertujuan untuk menentukan nilai EQ dari tindakan ESWL menggunakan mesin piezolith richard wolf 3000 pada batu ureter dan hubungan angka bebas batu dengan lokasi batu, jumlah batu, beban batu, opasitas batu, obstruksi, dan fungsi ginjal. Studi cross sectional ini dilakukan pada bulan Januari 2008-Desember 2011 dan data dianalisis dengan statistik multivariat. Terdapat 113 (95 % dari 119 pasien yang dinyatakan bebas batu setelah tindakan ESWL pertama. Didapatkan nilai EQ 0,89. Hanya ukuran batu yang mempengaruhi angka bebas batu dalam penelitian ini (p<0,05. Disimpulkan bahwa prosedur ESWL menggunakan mesin richard wolf piezolith 3000 memiliki nilai EQ dan angka bebas batu yang lebih baik daripada mesin-mesin sebelumnya dan mesin lain yang sejenis. Faktor yang mempengaruhi keberhasilan adalah ukuran batu ureter yang ditatalaksana.Kata Kunci: batu ureter, ESWL, efficacy quotient, angka bebas batu. Efficacy Quotient of ESWL Piezolith Richard Wolf 3000 Machine in Patientswith Ureteral Stones in Dr. Cipto MangunkusumoNational Hospital 2008 - 2011AbstractExtracorporeal shockwave lithotripsy (ESWL is the most common method of ureteral stone management. Since 2008, RSCM has ben using ESWL piezolith 3000 richard wolf and efficacy quotient (EQ value have not yet studied. The study aims was to determine the efficacy quotient (EQ of ESWL using piezolith richard wolf 3000 machine for ureteral stone by analyzing free-stone rate with location of stones, number of stones, stone burden, stone opacity, obstruction and kidney function. This cross sectional study was carried out in January 2008-December 2011, with multivariate analytical study. Ninety five percent (n=113 of 119 patients were

  19. Helicobacter sp. MIT 01-6451 infection during fetal and neonatal life in laboratory mice.

    Science.gov (United States)

    Yamanaka, Hitoki; Nakanishi, Tai; Takagi, Toshikazu; Ohsawa, Makiko; Kubo, Noriaki; Yamamoto, Naoto; Takemoto, Takahira; Ohsawa, Kazutaka

    2015-01-01

    Helicobacter sp. MIT 01-6451 has been detected in SPF mice kept in Japan. To characterize strain MIT 01-6451, its infection route during fetal and neonatal life and effects on pregnancy were investigated using immunocompetent and immunodeficient mouse strains (BALB/c, C57BL/6, and SCID). MIT 01-6451 was detected in the uterus, vagina, and mammary glands of 50% of infected SCID mice, whereas these tissues were all negative in immunocompetent mice. No fetal infections with MIT 01-6451 were detected at 16-18 days after pregnancy in any mouse strain. In newborn mice, MIT 01-6451 was detected in intestinal tissue of C57BL/6 and SCID mice at 9-11 days after birth, but not in BALB/c mice. The IgA and IgG titers to MIT 01-6451 in sera of C57BL/6 female mice were significantly lower than those of BALB/c mice. Although no significant differences in the number of newborns per litter were observed between MIT 01-6451-infected and MIT 01-6451-free dams, the birth rate was lower in infected SCID mice than in control SCID mice. The present results indicated that MIT 01-6451 infects newborn mice after birth rather than by vertical transmission to the fetus via the placenta and that MIT 01-6451 infection shows opportunistically negative effects on the birth rate. In addition, the maternal immune response may affect infection of newborn mice with MIT 01-6451 through breast milk.

  20. PREFACE: Celebrating 20 years of Journal of Physics: Condensed Matter—in honour of Richard Palmer Celebrating 20 years of Journal of Physics: Condensed Matter—in honour of Richard Palmer

    Science.gov (United States)

    Ferry, David; Dowben, Peter; Inglesfield, John

    2009-11-01

    This year marks the 20th anniversary of the launch of Journal of Physics: Condensed Matter in 1989. The journal was formed from the merger of Journal of Physics C: Solid State Physics and Journal of Physics F: Metal Physics which had separated in 1971. In the 20 years since its launch, Journal of Physics: Condensed Matter has more than doubled in size, while raising standards. Indeed, Journal of Physics: Condensed Matter has become one of the leading scientific journals for our field. This could not have occurred without great leadership at the top. No one has been more responsible for this growth in both size and quality than our Senior Publisher, Richard Palmer. Richard first started work at IOP in March 1971 as an Editorial Assistant with J. Phys. B After a few months, he transferred to J. Phys.C The following year, the Assistant Editor of J. Phys. C, Malcolm Haines, left suddenly in order to work on his family vineyard in France, and Richard stepped into the breach. In those days, external editors had a much more hands-on role in IOP Publishing and he had to travel to Harwell to be interviewed by Alan Lidiard, the Honorary Editor of J. Phys. C, before being given the job of Assistant Editor permanently. Since J. Phys. C and J. Phys. F re-merged to form Journal of Physics: Condensed Matter, Richard gradually shed his other journal responsibilities, except for Reports on Progress in Physics, to build up Journal of Physics: Condensed Matter. He has worked closely with four Editors-in-Chief of J. Phys. C and five of Journal of Physics: Condensed Matter. When Richard announced his retirement this past winter, we met it with a great deal of both happiness and sadness. Of course, we are happy that he is going to be allowed to enjoy his retirement, but we remain very sad to lose such a valuable member of our team, especially the one who had provided the heart and soul of the journal over its 20 years. We will be able to rely upon the team which Richard ably trained as

  1. Material Identification Technology (MIT) concept technical feasibility study

    International Nuclear Information System (INIS)

    Jones, J.L.; Harker, Y.D.; Yoon, W.Y.; Johnson, L.O.

    1993-09-01

    The Idaho National Engineering Laboratory (INEL) has initiated the design and development of a novel pulsed accelerator-based, active interrogation concept. The proposed concept, referred to as the Material Identification Technology (MIT), enables rapid (between accelerator pulses), non-destructive, elemental composition analysis of both nuclear and non-nuclear materials. Applications of this technique include material monitoring in support of counter-proliferation activities, such as export controls (at domestic and international inspection locations), SNM controls, nuclear weapon dismantlement, and chemical weapon verification. Material Identification Technology combines a pulsed, X-ray source (an electron accelerator) and a gamma detection system. The accelerator must maximize neutron production (pulse width, beam current, beam energy, and repetition rate) and minimize photon dose to the object. Current available accelerator technology can meet these requirements. The detection system must include detectors which provide adequate gamma energy resolution capability, rapid recovery after the initial X-ray interrogation pulse, and multiple single gamma event detection between accelerator pulses. Further research is required to develop the detection system. This report provides the initial feasibility assessment of the MIT concept

  2. MIT nuclear reactor laboratory high school teaching program

    International Nuclear Information System (INIS)

    Olmez, I.

    1991-01-01

    For the last 6 years, the Massachusetts Institute of Technology (MIT) Nuclear Reactor Laboratory's academic and scientific staff a have been conducting evening seminars for precollege science teachers, parents, and high school students from the New England area. These seminars, as outlined in this paper, are intended to give general information on nuclear technologies with specific emphasis on radiation physics, nuclear medicine, nuclear chemistry, and ongoing research activities at the MIT research reactor. The ultimate goal is to create interest or build on the already existing interest in science and technology by, for example, special student projects. Several small projects have already been completed ranging from environmental research to biological reactions with direct student involvement. Another outcome of these seminars was the change in attitudes of science teachers toward nuclear technology. Numerous letters have been received from the teachers and parents stating their previous lack of knowledge on the beneficial aspects of nuclear technologies and the subsequent inclusion of programs in their curriculum for educating students so that they may also develop a more positive attitude toward nuclear power

  3. Status of the MIT-Bates South Hall Ring commissioning

    International Nuclear Information System (INIS)

    Flanz, J.B.; Jacobs, K.D.; McAllister, B.; Averill, R.; Bradley, S.; Carter, A.; Dow, K.; Farkondeh, M.; Ihloff, E.; Kowalski, S.

    1993-01-01

    The MIT-Bates South Hall Ring construction project is now nearly complete. At this time the Energy Compression System, the SHR Injection Line and the South Hall Ring itself are complete. The SHR Extraction Line is complete but has not been connected to the ring. Commissioning with beam of the completed beam lines has been started. The MIT-Bates South Hall Ring (SHR) is an electron storage ring used with the 1 GeV Bates electron accelerator to increase the effective duty factor and luminosity. A beam can be stored for use with an internal target, thus allowing for high duty factor, high luminosity experiments. External beams with high duty factor can be obtained using resonant extraction. The new systems associated with the SHR include the Energy Compression System (ECS), the Injection line, and the Extraction line. The authors have commissioned the ECS, the new injection line and the SHR without RF. This includes transporting beam, measuring beam phase space parameters using critical injection elements including a high voltage electrostatic septum, a fast beam kicker, and storing a beam in the SHR

  4. Richards growth model and viability indicators for populations subject to interventions

    Directory of Open Access Journals (Sweden)

    Selene Loibel

    2010-12-01

    Full Text Available In this work we study the problem of modeling identification of a population employing a discrete dynamic model based on the Richards growth model. The population is subjected to interventions due to consumption, such as hunting or farming animals. The model identification allows us to estimate the probability or the average time for a population number to reach a certain level. The parameter inference for these models are obtained with the use of the likelihood profile technique as developed in this paper. The identification method here developed can be applied to evaluate the productivity of animal husbandry or to evaluate the risk of extinction of autochthon populations. It is applied to data of the Brazilian beef cattle herd population, and the the population number to reach a certain goal level is investigated.Neste trabalho estudamos o problema de identificação do modelo de uma população utilizando um modelo dinâmico discreto baseado no modelo de crescimento de Richards. A população é submetida a intervenções devido ao consumo, como no caso de caça ou na criação de animais. A identificação do modelo permite-nos estimar a probabilidade ou o tempo médio de ocorrência para que se atinja um certo número populacional. A inferência paramétrica dos modelos é obtida através da técnica de perfil de máxima verossimilhança como desenvolvida neste trabalho. O método de identificação desenvolvido pode ser aplicado para avaliar a produtividade de criação animal ou o risco de extinção de uma população autóctone. Ele foi aplicado aos dados da população global de gado de corte bovino brasileiro, e é utilizado na investigação de a população atingir um certo número desejado de cabeças.

  5. Mobile-IT Education (MIT.EDU): M-Learning Applications for Classroom Settings

    Science.gov (United States)

    Sung, M.; Gips, J.; Eagle, N.; Madan, A.; Caneel, R.; DeVaul, R.; Bonsen, J.; Pentland, A.

    2005-01-01

    In this paper, we describe the Mobile-IT Education (MIT.EDU) system, which demonstrates the potential of using a distributed mobile device architecture for rapid prototyping of wireless mobile multi-user applications for use in classroom settings. MIT.EDU is a stable, accessible system that combines inexpensive, commodity hardware, a flexible…

  6. MIT domain of Vps4 is a Ca2+-dependent phosphoinositide-binding domain.

    Science.gov (United States)

    Iwaya, Naoko; Takasu, Hirotoshi; Goda, Natsuko; Shirakawa, Masahiro; Tanaka, Toshiki; Hamada, Daizo; Hiroaki, Hidekazu

    2013-05-01

    The microtubule interacting and trafficking (MIT) domain is a small protein module that is conserved in proteins of diverged function, such as Vps4, spastin and sorting nexin 15 (SNX15). The molecular function of the MIT domain is protein-protein interaction, in which the domain recognizes peptides containing MIT-interacting motifs. Recently, we identified an evolutionarily related domain, 'variant' MIT domain at the N-terminal region of the microtubule severing enzyme katanin p60. We found that the domain was responsible for binding to microtubules and Ca(2+). Here, we have examined whether the authentic MIT domains also bind Ca(2+). We found that the loop between the first and second α-helices of the MIT domain binds a Ca(2+) ion. Furthermore, the MIT domains derived from Vps4b and SNX15a showed phosphoinositide-binding activities in a Ca(2+)-dependent manner. We propose that the MIT domain is a novel membrane-associating domain involved in endosomal trafficking.

  7. Scratch that: MIT's Mitchel Resnick Says Kids Should Do It for Themselves

    Science.gov (United States)

    Traylor, Scott

    2008-01-01

    Mitchel Resnick is a researcher, inventor, and professor at MIT's Media Laboratory in Cambridge, MA, and the founder of the Lifelong Kindergarten Group at MIT. He is the lead innovator behind many cutting-edge learning technologies and projects for children, including the Computer Clubhouse, PicoCrickets, and the wildly successful consumer…

  8. Assessing International Product Design and Development Graduate Courses: The MIT-Portugal Program

    Science.gov (United States)

    Dori, Yehudit Judy; Silva, Arlindo

    2010-01-01

    The Product Design and Development (PDD) course is part of the graduate curriculum in the Engineering Design and Advanced Manufacturing (EDAM) study in the MIT-Portugal Program. The research participants included about 110 students from MIT, EDAM, and two universities in Portugal, Instituto Superior Técnico-Universidade Técnica de Lisboa (IST) and…

  9. Analyse von Kunststoffadditiven mittels Laserablation gekoppelt mit induktiv gekoppelter Plasma Massenspektrometrie

    OpenAIRE

    Börno, Fabian

    2016-01-01

    Die Laserablation gekoppelt mit der Massenspektrometrie mit induktiv gekoppeltem Plasma ist eine vielversprechende direkte Feststofftechnik, die sich jedoch bei der Analyse von Kunststoffen wegen des Mangels an matrixangepassten zertifizierten Referenzmaterialien nicht durchsetzen konnte. Vorherige Arbeiten belegen polymerabhängige Abtragsraten. Das oft als interner Standard verwendete Intensitätssignal des Kohlenstoffisotopes 13C zur Korrektur dieser Unterschiede wird in der Literatur kritis...

  10. Der Entwurf einer Musterwohnung für ältere Menschen mit Demenz

    NARCIS (Netherlands)

    Joost van Hoof

    2014-01-01

    Einführung Ältere Menschen mit Demenz brauchen Wohnungen, die sowohl altersgemäß ausgestattet sind als auch die erforderliche Pflege im Haus anbieten. Traditionelle Änderungen und entsprechende Technologien bieten in erster Linie Lösungen für Personen mit eingeschränkter Mobilität. Dies bedeutet,

  11. Klinische Ergebnisse in der Behandlung der rezidivierenden respiratorischen Papillomatose mit Microdebrider, intraläsionaler Cidofovir-Injektion und Impfung mit Gardasil

    OpenAIRE

    Schäfer, Fabian Axel

    2013-01-01

    Die Rekurrierende Respiratorische Papillomatose (RRP) ist eine seltene Erkrankung, die Kinder, aber auch Erwachsene betrifft. Sie ist charakterisiert durch eine Proliferation benigner Plattenepithel-Papillome innerhalb des Aerodigestiv-Traktes mit dem Larynx als Prädilektionsstelle. Hervorgerufen wird die RRP durch eine orale Infektion mit Humanen Papillomviren (HPV) der Typen 6 oder 11. Bei aggressiven Verlaufsformen, die eine Vielzahl von Papillomabtragungen im Abstand von wenigen Monaten o...

  12. Parallelization Experience with Four Canonical Econometric Models Using ParMitISEM

    Directory of Open Access Journals (Sweden)

    Nalan Baştürk

    2016-03-01

    Full Text Available This paper presents the parallel computing implementation of the MitISEM algorithm, labeled Parallel MitISEM. The basic MitISEM algorithm provides an automatic and flexible method to approximate a non-elliptical target density using adaptive mixtures of Student-t densities, where only a kernel of the target density is required. The approximation can be used as a candidate density in Importance Sampling or Metropolis Hastings methods for Bayesian inference on model parameters and probabilities. We present and discuss four canonical econometric models using a Graphics Processing Unit and a multi-core Central Processing Unit version of the MitISEM algorithm. The results show that the parallelization of the MitISEM algorithm on Graphics Processing Units and multi-core Central Processing Units is straightforward and fast to program using MATLAB. Moreover the speed performance of the Graphics Processing Unit version is much higher than the Central Processing Unit one.

  13. Who invented the dichotomous key? Richard Waller's watercolors of the herbs of Britain.

    Science.gov (United States)

    Griffing, Lawrence R

    2011-12-01

    On 27 March 1689, Richard Waller, Fellow and Secretary of the Royal Society presented his "Tables of the English Herbs reduced to such an order, as to find the name of them by their external figures and shapes" to his assembled colleagues at a meeting of the Royal Society. These tables were developed for the novice by being color images, composed in pencil and watercolor, of selected plants and their distinguishing characteristics. The botanical watercolors for the tables are now a Turning-the-Pages document online on the website of the Royal Society. However, for the past 320 years, the scientific context for the creation of these outstanding botanical watercolors has remained obscure. These tables were developed by Waller as an image-based dichotomous key, pre-dating by almost 100 years the text-based dichotomous keys in the first edition of Flora Française (1778) by Jean Baptiste Lamarck, who is generally given priority for the development of the dichotomous key. How these large folio images were arranged to illustrate a dichotomous key is unknown, but an arrangement based on Waller's description is illustrated here as leaf-ordering for the separate hierarchical clusters (tables). Although only 24 species of watercolored dicot herbs out of a total of 65 in the set of watercolors (the others being monocots) are used in these tables, they are a "proof of concept", serving as models upon which a method is based, that of using a key composed of dichotomous choices for aiding identification.

  14. Símbolo y forma: los hermanos Grimm en Richard Wagner

    Directory of Open Access Journals (Sweden)

    Miguel Salmerón Infante

    2015-05-01

    Full Text Available Este escrito estudia el cómo y el porqué de la presencia de los Cuentos de los Hermanos Grimm en la obra de Richard Wagner. Para dar un enfoque más concreto a esta reflexión el análisis se centra en Sigfrido, el drama musical de Wagner con más atmósfera de cuento, y las influencias y préstamos temáticos, formales y lingüísticos que le aportan los KHM. El artículo entiende que hay dos elementos que aprovecha Wagner de los Grimm para sus dramas musicales. El símbolo para su proyecto de tejido de la identidad alemana. Y la forma del cuento con sus temas y fórmulas recurrentes que el aplicó a su música y muy concretamente al Leitmotiv. Todo ello sin olvidar la muy frecuente presencia de la figura del huérfano tanto en Wagner como en los Grimm.  

  15. Staging Unincorporated Power: Richard Harding Davis and the Critique of Imperial News

    Directory of Open Access Journals (Sweden)

    Nirmal Trivedi

    2011-12-01

    Full Text Available This essay contextualizes the work of war correspondent Richard Harding Davis within an evolving “imperial news apparatus” that would culminate in his reporting of the Spanish-American War. Critics have conventionally framed Davis squarely within the imperial cause, associating him with his admirer Roosevelt and naval admiral Alfred T. Mahan. Contrary to readings of Davis as an apologist for US imperialism, Trivedi contends that Davis understood how US imperial power relied on an information apparatus to communicate to an increasingly media-conscious American public through culture, that is, via familiar narratives, symbols, and objects—what Trivedi calls “imperial news.” The essay follows Davis’s development from his fictional representation of the new war correspondent in “The Reporter Who Made Himself King” to his own war correspondence before and after the Spanish-American War as collected in the memoirs A Year from a Reporter’s Notebook (1897, Cuba in War Time (1897, and Notes of a War Correspondent (1912. Davis’s war correspondence and fictional work effectively stage US imperialism as “unincorporated power”: that is, as power reliant on a developing news-making apparatus that deploys particular discursive strategies to validate its political claims. This staging critiques strategies of US imperial sovereignty—specifically its “privatization of knowledge” and its promotion of the war correspondent as nothing more than a spectator and purveyor of massacres.

  16. Meeting to honor F. Richard Stephenson on his 70th birthday

    CERN Document Server

    Green, David; Strom, Richard

    2015-01-01

    This book contains papers from a conference held to celebrate the 70th birthday of one of the world’s foremost astronomical historians, Professor F. Richard Stephenson, the latest recipient of the American Astronomical Society’s highest award for research in astronomical history, the LeRoy Doggett Prize. Reflecting Professor Stephenson’s extensive research portfolio, this book brings together under one cover papers on four different areas of scholarship: applied historical astronomy (which Stephenson founded); Islamic astronomy; Oriental astronomy; and amateur astronomy.  These papers are penned by astronomers from Canada, China, England, France, Georgia, Iran, Japan, Lebanon, the Netherlands, Portugal, Thailand and the USA. Its diverse coverage represents a wide cross-section of the history of astronomy community.  Under discussion are ways in which recent research using historical data has provided new insights into auroral and solar activity, supernovae and changes in the rotation rate of the E...

  17. Against the Nihilism of Suffering and Death: Richard E. K. Kim and His Works

    Directory of Open Access Journals (Sweden)

    Jooyeon Rhee

    2016-03-01

    Full Text Available This article examines the life and works of Richard E. K. Kim (1932–2009, a first-generation Korean diasporic writer in the United States. It focuses on how Kim struggled to overcome the nihilism of suffering and death that derived from colonialism and the Korean War through his literary works. Kim witnessed firsthand these two major historical events, which caused irrevocable psychological and physical damage to many people of his generation. In his autobiographical fiction, he conveys painful memories of the events by reviving the voices of people in that era. What his works offer us goes beyond vivid memories of the past, however; they also present the power of forgiveness as a condition to overcome the nihilism of suffering and death. Remembrance and forgiveness are, therefore, two major thematic pillars of his works that enable us to connect to these difficult and traumatic times. These themes are portrayed in such a gripping way mainly because Kim tried to maintain a certain distance—an emotional and linguistic distance—from the familiar, in order to elucidate the reality of the human condition: an ontological position of the exile from which he produced his works. This article argues that Kim’s works provide us the possibility to transcend the nihilism of historical trauma through articulating the meaning of remembrance and forgiveness from his self-assumed position of exile.

  18. Providing the physical basis of SCS curve number method and its proportionality relationship from Richards' equation

    Science.gov (United States)

    Hooshyar, M.; Wang, D.

    2016-12-01

    The empirical proportionality relationship, which indicates that the ratio of cumulative surface runoff and infiltration to their corresponding potentials are equal, is the basis of the extensively used Soil Conservation Service Curve Number (SCS-CN) method. The objective of this paper is to provide the physical basis of the SCS-CN method and its proportionality hypothesis from the infiltration excess runoff generation perspective. To achieve this purpose, an analytical solution of Richards' equation is derived for ponded infiltration in shallow water table environment under the following boundary conditions: 1) the soil is saturated at the land surface; and 2) there is a no-flux boundary which moves downward. The solution is established based on the assumptions of negligible gravitational effect, constant soil water diffusivity, and hydrostatic soil moisture profile between the no-flux boundary and water table. Based on the derived analytical solution, the proportionality hypothesis is a reasonable approximation for rainfall partitioning at the early stage of ponded infiltration in areas with a shallow water table for coarse textured soils.

  19. Unreliability and the Animal Narrator in Richard Adams’s The Plague Dogs

    Directory of Open Access Journals (Sweden)

    Anja Höing

    2017-03-01

    Full Text Available Richard Adams’s talking animal story The Plague Dogs (1978, with its deeply genre-atypical mode of narration, offers a multiplicity of avenues to explore the literary animal as animal. The story draws much of its power from the psychological complexity and related unreliability of both canine narrators, two research lab escapees gone feral. Both the terrier Snitter and the black mongrel Rowf are mentally ill and experience a highly subjective, part-fantastic world. In episodes of zero focalization, a sarcastic voice comments on the plot from the off, aggressively attacking a thoroughly anthropocentric superstructure the protagonists themselves are oblivious of, and presenting all that is normally constructed as “rational” in the implied reader’s world as a carnivalesque farce. Combining these equally unreliable narratives, The Plague Dogs creates a unique mixture of what Phelan (2007 calls “estranging” and “bonding” unreliability and brings to light the devastating consequences of anthropocentrism. The Plague Dogs not only defamiliarizes a genre usually committed to conventional means of storytelling, but the dominant Western conception of the status of animals in the world, showing that once we start to read the animal as animal, this sets into motion an avalanche of other concepts in need of re-reading, among them the very ones making up the fundamental pillars of Western societies’ anthropocentric self-conception.

  20. Perbandingan antara Etika Jürgen Habermas dan Richard Rorty sebagai Prinsip Dasar Bertindak Manusia

    Directory of Open Access Journals (Sweden)

    Dominique Rio Adiwijaya

    2010-10-01

    Full Text Available Ethics without doubt is an issue in every scientific field. Questions on ethics are not merely questions on the responsibility of one or two specific individuals, but rather as what have been defined accurately by Immanuel Kant in Critique of Practical Reason – as question of all humanity as a thinking creature and the freedom of choice on, “what should I do”. From Kant’s definition, we may infer that if human can not think and not free in determining their choice, it would be almost impossible to hope for moral responsibility. However this article does not mean to give a full and historical description on ethics, but a sketch on discourse of contemporary ethics which is represented by two famous philosophers, Jürgen Habermas from the tradition of  Critical Theory from Frankfurt School, dan Richard Rorty with “Neo-Pragmatism”. Habermas proposes “discourse ethics” while Rorty proposes ethic concepts through his “liberal-ironists”. It is hoped that the assembly of readers may gain an insight of the unavoidable ethics problems since every ethical position must be theory laden and the theory itself has historical characteristics (the characteristics, origin and historical context of the schools behind it. Therefore ethics is a neverending reflection although it has been started from 2500 years ago. Ethics invites us from specific sciences to enter its general discourse which unavoidably all-encompassing in its nature. 

  1. Richard Rorty:From Anti-metaphysical Neo-Pragmatism to Rejection of Philosophy

    Directory of Open Access Journals (Sweden)

    M. Akrami

    2010-01-01

    Full Text Available Richard Rorty is a neo-Pragmatist philosopher. For three decades, he has attacked the traditional philosophy (from Plato to Kant as well as any other epistemology searching for truth or claiming to mirror the nature in his philosophical works. Rorty holds that, according to the history of philosophy in his reading, there is no final answer to the traditional questions concerning knowledge, truth, and representation. These questions, therefore, should be dissolved and denied. He maintains that knowledge is justified belief, justification, however, being not the consequence of some correspondence between the theory or the statement, but the consequence of conversation, social practice, group consensus, and social solidarity. Rorty also thinks that democracy has priority on philosophy, disagreeing with the thesis that philosophy is the foundation of the rest of culture.Despite of usefulness of some elements and implications of Rorty’s metaphilosophy (such as his emphasis on freedom, democracy, and pluralism as well as his insisting on philosophical humility and avoiding scientific pride, it is faced with several problems, including 1 ignoring the referential and realist features of language, 2 confusing interpretation and reality, 3 eliminating the border between objectivity and subjectivity, 4 interfering of public and private life, and 5 ignoring the need of science, culture, technology and, in particular, politics, in philosophy. The authors try to show and analyze some elements of these problems.

  2. Has David Howden Vindicated Richard von Mises’s Definition of Probability?

    Directory of Open Access Journals (Sweden)

    Mark R. Crovelli

    2009-11-01

    Full Text Available In my recent article on these pages (Crovelli 2009 I argued that members of the Austrian School of economics have adopted and defended a faulty definition of probability. I argued that the definition of probability necessarily depends upon the nature of the world in which we live. I claimed that if the nature of the world is such that every event and phenomenon which occurs has a cause of some sort, then probability must be defined subjectively; that is, “as a measure of our uncertainty about the likelihood of occurrence of some event or phenomenon, based upon evidence that need not derive solely from past frequencies of ‘collectives’ or ‘classes.’” I further claimed that the nature of the world is indeed such that all events and phenomena have prior causes, and that this fact compels us to adopt a subjective definition of probability.David Howden has recently published what he claims is a refutation of my argument in his article “Single Trial Probability Applications: Can Subjectivity Evade Frequency Limitations” (Howden 2009. Unfortunately, Mr. Howden appears to not have understood my argument, and his purported refutation of my subjective definition consequently amounts to nothing more than a concatenation of confused and fallacious ideas that are completely irrelevant to my argument. David Howden has thus failed in his attempt to vindicate Richard von Mises’s definition of probability.

  3. Blood, politics, and social science. Richard Titmuss and the Institute of Economic Affairs, 1957-1973.

    Science.gov (United States)

    Fontaine, Philippe

    2002-09-01

    Long before his last book, The Gift Relationship: From Human Blood to Social Policy, was published in early 1971, Richard M. Titmuss (1907-1973), a professor of social administration at the London School of Economics, had been a major figure in the debates over the welfare state. The Gift Relationship was the culmination of an eventful relationship with the Institute of Economic Affairs, a think tank that advocated the extension of rational pricing to social services. By arguing that the British system of blood procurement and distribution, based on free giving within the National Health Service, was more efficient than the partly commercialized American system, Titmuss intended to signal the dangers of the increasing commercialization of society. What made for the impact of his book, however, was not merely its argument that transfusion-transmitted infections were much more common with paid than with voluntary donors, but also its reflections on what it is that holds a society together. And here Titmuss argued that a "socialist" social policy, by encouraging the sense of community, played a central role. The eclecticism of Titmuss's work, together with its strong ethical and political flavor, makes it a rich and original account of the "social" at a time when heated debated over social policy, both in Britain and in the United States, raised the question of the division of labor among the social sciences.

  4. First record of the Asian diaptomid Neodiaptomus schmackeri (Poppe & Richard, 1892 (Crustacea: Copepoda: Calanoida in Europe

    Directory of Open Access Journals (Sweden)

    Giuseppe Alfonso

    2014-06-01

    Full Text Available Albania, as well as a great part of the Balkan area in general, still suffers a lack of environmental studies especially in limnological research. The Dumre plateau, in Central Albania, is characterized by an extraordinary high number of karst lakes in a small geographic area. Despite their environmental peculiarity, very few biological data are to date available for these lakes, none on the zooplankton. For this reason, 15 water bodies located in the central area of the plateau were selected for a preliminary limnological survey carried out in the years 2008-2011. Neodiaptomus schmackeri (Poppe & Richard, 1892, a diaptomid calanoid copepod characterized by a South-Eastern Palearctic - Oriental distribution, and the most widely spread Neodiaptomus species in Asia, was found in 8 lakes of the Dumre area. This finding represents the first record of the species, and of the entire genus Neodiaptomus, for Europe. Several environmental variables were measured to characterize the lakes, and the co-occurring planktonic crustaceans were also identified. Taxonomical drawings and descriptions of the main morphological features of both sexes are herein provided in order to compare the Albanian populations of N. schmackeri with those of the native distribution area of the species. The possible causes which determined the occurrence of this non-indigenous species in several Dumre lakes are discussed.

  5. Health Effects Due to Radionuclides Content of Solid Minerals within Port of Richards Bay, South Africa

    Directory of Open Access Journals (Sweden)

    Felix B. Masok

    2016-11-01

    Full Text Available This study assessed the radiological health hazards to various body organs of workers working within Transnet Precinct in Richards Bay in Kwazulu-Natal, South Africa due to radionuclide content of mineral ores often stored within the facility. Thirty samples were collected from five mineral ores (rock phosphate, rutile, zircon, coal and hematite and analyzed for 238U, 234U, 226Ra, 210Pb, 235U, 232Th, 228Ra, 228Th and 40K using delayed neutron activation analysis and low energy gamma spectroscopy. Rutile was found to be the most radioactive mineral ore within the facility with 210Pb concentration of 759.00 ± 106.00 Bq·kg−1. Effective annual dose rate in (mSv·y−1 delivered to different organs of the body: testes, bone marrow, whole body, lungs and ovaries from mineral ores were such that dose from mineral ores decreased in the order coal > rutile > rock phosphate > hematite > zircon. The organs with the highest received dose rate were the testes and this received dose was from coal. However, all of the calculated absorbed dose rates to organs of the body were below the maximum permissible safety limits.

  6. “This World Is Not My Home”: Richard Mouw and Christian Nationalism

    Directory of Open Access Journals (Sweden)

    Aaron Pattillo-Lunt

    2016-12-01

    Full Text Available American evangelicalism has often been punctuated by dual commitments to the United States and to God. Those commitments were strongest within politically conservative evangelicalism. Though representing a solid majority among professing evangelicals, conservatives could not speak for the movement as a whole. Politically progressive evangelicals, beginning in the 1960s, formed a dissenting opinion of the post-World War II revival of Christian nationalism. They dared to challenge American action abroad, noticeably during the Vietnam War. Their critique of Christian nationalism and conservative evangelicals’ close ties to the Republican Party led them to seek refuge in either progressive policies or the Democratic Party. A third, underexplored subgroup of evangelicalism rooted in reformed theology becomes important to consider in this regard. These reformed evangelicals sought to contextualize nationalism in biblical rather than partisan or political terms. This goal is championed well by Richard Mouw, resulting in a nuanced look at evangelical Christians’ difficult dual role as both citizens of the Kingdom of God and the United States.

  7. Poets/Trump/Philosophers: Reflections on Richard Rorty’s Liberalism, Ten Years after His Death

    Directory of Open Access Journals (Sweden)

    Giorgio Baruchello

    2017-08-01

    Full Text Available Starting with a prescient 1998 quote on the impending decline of US liberal democracy into right-wing, strong-man-based demagogy, this paper outlines Richard Rorty’s political philosophy, which I believe can help us understand perplexing political trends in today’s political reality well beyond the US alone. Specifically, I tackle three key-terms encapsulating the thrust of Rorty’s political philosophy, i.e. “liberalism of fear”, “bourgeois” and “postmodernism”. Also, I address a contraposition that explains how Rorty would approach and attempt to defend liberal democracy from contemporary right-wing, strong-man-based degenerations, namely the priority of “poetry” over “philosophy”. Essentially, if one wishes to win in the political arena, she must be armed with the most effective rhetorical weaponry, however good, solid and well-argued her political views may be. Finally, some remarks are offered on the role that “philosophy” can still play within the same arena.

  8. Arctic observers: Richard King, monogenism and the historicisation of Inuit through travel narratives.

    Science.gov (United States)

    Sera-Shriar, Efram

    2015-06-01

    In 1848 the ethnologist, surgeon and Arctic explorer Richard King (1810-1876) published a three-part series on Inuit in the Journal of the Ethnological Society of London. This series provided a detailed history of Inuit from the eleventh century to the early nineteenth century. It incorporated a mixture of King's personal observations from his experience travelling to the Arctic as a member of George Back's expedition (1833-1835), and the testimonies of other contemporary and historical actors who had written on the subject. The aim was to historicise Inuit through the use of travel reports and show persistent features among the race. King was a monogenist and his sensitive recasting of Inuit was influenced by his participation in a research community actively engaged in humanitarian and abolitionist causes. The physician and ethnologist Thomas Hodgkin (1798-1866) argued that King's research on Inuit was one of the best ethnological approaches to emulate and that it set the standard for the nascent discipline. If we are to take seriously Hodgkin's claim, we should look at how King constructed his depiction of Inuit. There is much to be gained by investigating the practices of nineteenth-century ethnologists because it strengthens our knowledge of the discipline's past and shows how modern understandings of races were formed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. [R]MIT Research Centre at Delft University of Technology: A Bridge between Research, Education, Society and Profession

    Science.gov (United States)

    Zijlstra, Hielkje

    2009-01-01

    In 2006, we launched the [R]MIT Research Centre (Modification, Intervention Transformation) at the Faculty of Architecture at Delft University of Technology. [R]MIT was founded to respond to the need for an integrated, multi-disciplinary approach to the transformation of the built environment. [R]MIT aims to bring momentum to the renewal of…

  10. Predicting material failure using mathematics; Mit Mathematik Materialversagen vorhersagen

    Energy Technology Data Exchange (ETDEWEB)

    Keller, Christian [Bundesanstalt fuer Materialforschung und -pruefung (BAM), Berlin (Germany)

    2016-06-15

    Numerical simulations provide insights into materials, technical procedures or processes that are hardly possible by means of measurement technology, or require a lot of effort. In BAM's ConDrop research project (Numerical Drop Test Analyses of Steel Sheet Containers for the Konrad Repository), scientists are developing a method to predict the deformation and failure behaviour of containers for low- and intermediate- level radioactive waste for the Konrad repository. [German] Numerische Simulationen erlauben Einblicke in Materialien, technische Verfahren oder Prozesse, die mit Mitteln der Messtechnik kaum oder nur unter grossem Aufwand moeglich sind. Im BAM-Forschungsvorhaben ConDrop entwickeln Wissenschaftlerinnen und Wissenschaftler damit eine Methode, um das Verformungs- und Versagensverhalten von Behaeltern fuer schwach- und mittelradioaktive Abfaelle fuer das Endlager Konrad vorherzusagen.

  11. Operating experience with innovative environmental technologies; Betriebserfahrungen mit innovativen Umwelttechnologien

    Energy Technology Data Exchange (ETDEWEB)

    Spindler, H.; Bauermeister, U.; Kliche, H.; Seiffarth, K. (comps.)

    2000-03-01

    The MUT '99 (Merseburger Umwelt-Tag) discussed modern processes, technologies and plants for treatment and utilisation of waste. The conference was attended by industrial organisations and scientific institutions. [German] Der 9. Merseburger Umwelt-Tag MUT '99 steht unter dem Motto 'Betriebserfahrungen mit innovativen Umwelttechnologien - Moderne wirtschaftliche Verfahren, Technologien und Anlagen zur Behandlung/Verwertung nichtvermeidbaren Abfalls', wobei der Begriff 'Abfall' sich letztlich auf alle Umweltmedien bezieht. Entsprechend dem Motto dieser Tagung stellen Unternehmen, Betriebe und wissenschaftliche Einrichtungen ihre Erfahrungen auf dem Gebiet der Umwelttechnologien vor, um Entwicklungen auf diesem Gebiet einer breiten Diskussion zu eroeffnen. Dabei soll es insbesondere um die Behandlung nicht vermeidbarer Abfaelle und Abwaesser gehen. (orig.)

  12. LLIMAS: Revolutionizing integrating modeling and analysis at MIT Lincoln Laboratory

    Science.gov (United States)

    Doyle, Keith B.; Stoeckel, Gerhard P.; Rey, Justin J.; Bury, Mark E.

    2017-08-01

    MIT Lincoln Laboratory's Integrated Modeling and Analysis Software (LLIMAS) enables the development of novel engineering solutions for advanced prototype systems through unique insights into engineering performance and interdisciplinary behavior to meet challenging size, weight, power, environmental, and performance requirements. LLIMAS is a multidisciplinary design optimization tool that wraps numerical optimization algorithms around an integrated framework of structural, thermal, optical, stray light, and computational fluid dynamics analysis capabilities. LLIMAS software is highly extensible and has developed organically across a variety of technologies including laser communications, directed energy, photometric detectors, chemical sensing, laser radar, and imaging systems. The custom software architecture leverages the capabilities of existing industry standard commercial software and supports the incorporation of internally developed tools. Recent advances in LLIMAS's Structural-Thermal-Optical Performance (STOP), aeromechanical, and aero-optical capabilities as applied to Lincoln prototypes are presented.

  13. Mitä uutta Oulun ravintolatarjontaan? : markkinatutkimus uutta ravintolaa ajatellen

    OpenAIRE

    Korhonen, Kerttu

    2014-01-01

    Tämä opinnäytetyö käsittelee Oulun alueelle tehtävää markkinatutkimusta nuorten ravintolakäyttäytymisestä ja – toiveista. Tutkimuskysymys kuuluu: ”Millaista uutta ravintolaa nuoret kaipaavat Oulun ravintolamaailmaan?”. Tutkimus on tehty ajatellen uuden ravintolan perustamista. Markkinatutkimuksella selvitetään opiskelevien nuorten toiveita siitä, mitä hyvä ravintola pitää sisällään. Tutkimuksen avulla selvitetään myös kuinka paljon nuoret käyttävät rahaa ravintolakäynneillään sekä sitä, kuink...

  14. X-ray cross-sections and crossroads (The International Radiation Physics Society) - Richard Pratt's contributions to both

    International Nuclear Information System (INIS)

    Hubbell, J.H.

    2000-01-01

    Some examples of the impact of the theoretical contributions by Richard Pratt and his collaborators on photon cross section compilations at NBS/NIST and elsewhere over the past several decades are presented. Both the theoretical and measurement works which combine to provide this data base, and the contact with the varied user groups in medical applications, nuclear engineering, crystallography and X-ray astronomy, have formed a global crossroads of researchers now embodied in the International Radiation Physics Society (IRPS). Since the founding of the IRPS at the 3 rd International Symposium on Radiation Physics (ISRP-3) in Ferrara, Italy, in 1985, the Secretariat for this 'global radiation physics family' (the IRPS) has resided at the University of Pittsburgh under the direction of Richard Pratt. A brief account of the origins and history of the IRPS, beginning with ISRP-1 in Calcutta in 1974, is presented.

  15. X-ray cross-sections and crossroads (The International Radiation Physics Society) - Richard Pratt's contributions to both

    Science.gov (United States)

    Hubbell, J. H.

    2000-08-01

    Some examples of the impact of the theoretical contributions by Richard Pratt and his collaborators on photon cross section compilations at NBS/NIST and elsewhere over the past several decades are presented. Both the theoretical and measurement works which combine to provide this data base, and the contact with the varied user groups in medical applications, nuclear engineering, crystallography and X-ray astronomy, have formed a global crossroads of researchers now embodied in the International Radiation Physics Society (IRPS). Since the founding of the IRPS at the 3rd International Symposium on Radiation Physics (ISRP-3) in Ferrara, Italy, in 1985, the Secretariat for this ``global radiation physics family'' (the IRPS) has resided at the University of Pittsburgh under the direction of Richard Pratt. A brief account of the origins and history of the IRPS, beginning with ISRP-1 in Calcutta in 1974, is presented.

  16. Plattenepithelkarzinom in Verbindung mit einer roten Tätowierung.

    Science.gov (United States)

    Schmitz, Inge; Prymak, Oleg; Epple, Matthias; Ernert, Carsten; Tannapfel, Andrea

    2016-06-01

    Obwohl Tätowierungen in den letzten Jahren außerordentlich beliebt geworden sind, wurde in der Literatur bisher nur über wenige Fälle schwerer Reaktionen berichtet, die zu einer malignen Transformation führten. Dies steht im Kontrast zu der praktisch unüberschaubaren Zahl an Tätowierungen weltweit. Die Zusammensetzung der für Tätowierungen verwendeten Farbstoffe variiert stark, und selbst gleiche Farbtöne können unterschiedliche Komponenten enthalten. Das Ziel unserer Studie war es zu untersuchen, auf welche Weise Tätowierungen möglicherweise Hautkrebs auslösen können. Wir berichten über den seltenen Fall einer 24-jährigen Frau, bei der sich sieben Monate nachdem sie eine Tätowierung auf dem Fußrücken erhalten hatte in unmittelbarer Nähe des verwendeten roten Farbstoffs ein Plattenepithelkarzinom entwickelte. Die Komplikationen begannen mit einer unspezifischen Schwellung. Die Läsion wurde histologisch untersucht. Die Zusammensetzung des inkorporierten Farbstoffs wurde mittels Rasterelektronenmikroskopie in Kombination mit energiedispersiver Elementanalyse analysiert. Zur weiteren Charakterisierung wurden Thermogravimetrie und Pulverdiffraktometrie eingesetzt. Der Tätowierungsfarbstoff enthielt hauptsächlich Bariumsulfat; Spuren von Al, S, Ti, P, Mg und Cl ließen sich ebenfalls nachweisen. Bei der Analyse zeigten sich Pigmentgranula unterschiedlicher Größe. In seltenen Fällen kann Tätowierungstinte karzinogene Effekte haben, die multifaktoriell zu sein scheinen. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  17. MiT family translocation renal cell carcinoma.

    Science.gov (United States)

    Argani, Pedram

    2015-03-01

    The MiT subfamily of transcription factors includes TFE3, TFEB, TFC, and MiTF. Gene fusions involving two of these transcription factors have been identified in renal cell carcinoma (RCC). The Xp11 translocation RCCs were first officially recognized in the 2004 WHO renal tumor classification, and harbor gene fusions involving TFE3. The t(6;11) RCCs harbor a specific Alpha-TFEB gene fusion and were first officially recognized in the 2013 International Society of Urologic Pathology (ISUP) Vancouver classification of renal neoplasia. These two subtypes of translocation RCC have many similarities. Both were initially described in and disproportionately involve young patients, though adult translocation RCC may overall outnumber pediatric cases. Both often have unusual and distinctive morphologies; the Xp11 translocation RCCs frequently have clear cells with papillary architecture and abundant psammomatous bodies, while the t(6;11) RCCs frequently have a biphasic appearance with both large and small epithelioid cells and nodules of basement membrane material. However, the morphology of these two neoplasms can overlap, with one mimicking the other. Both of these RCCs underexpress epithelial immunohistochemical markers like cytokeratin and epithelial membrane antigen (EMA) relative to most other RCCs. Unlike other RCCs, both frequently express the cysteine protease cathepsin k and often express melanocytic markers like HMB45 and Melan A. Finally, TFE3 and TFEB have overlapping functional activity as these two transcription factors frequently heterodimerize and bind to the same targets. Therefore, on the basis of clinical, morphologic, immunohistochemical, and genetic similarities, the 2013 ISUP Vancouver classification of renal neoplasia grouped these two neoplasms together under the heading of "MiT family translocation RCC." This review summarizes our current knowledge of these recently described RCCs. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Pathophysiologie des Kollagenstoffwechsels bei Patienten mit Induratio penis plastica (IPP

    Directory of Open Access Journals (Sweden)

    Lahme S

    2000-01-01

    Full Text Available Die Pathogenese der IPP ist bis heute nicht geklärt. Histopathologische Untersuchungen zeigen, daß der Kollagenstoffwechsel eine Rolle spielt. Dies veranlaßte uns zur genauen Analyse der Kollagenstoffwechselparameter bei IPP. Bei 11 Patienten mit IPP und 11 Kontrollpersonen wurden Kollagenstoffwechselparameter (Prokollagen III [PIIIP], PMN-Elastase [PMN-E], Fibronektin [FN], Fibronektinrezeptor [FN-R] und alpha1-Proteinase-Inhibitor [alpha1-PI] im cavernösen und peripheren Blut bestimmt. PMN-E, PIIIP, FN und FN-R waren in den beiden Untersuchungsgruppen nicht unterschiedlich. Die peripher venösen unterschieden sich nicht von den cavernösen Blutproben. Sowohl im peripher venös (158,55 mg/dl als auch im cavernös entnommenen Blut (168,29 mg/dl war die Konzentration des a1-PI signifikant niedriger als in der Kontrollgruppe (214,82 mg/dl. An einem zweiten Kollektiv von 23 Patienten wurden Analysen des Phänotyps für alpha1-PI im Hinblick auf das Vorliegen von genetisch determinierten Mangelallelen vorgenommen. Hier zeigte sich kein signifikanter Unterschied zu einem Kontrollkollektiv von 19 gesunden Probanden. Die alpha1-PI Erniedrigung der IPP-Patienten ist signifikant und liegt unterhalb des Normalwertbereichs für die gesunde Population. Ein Mangel an alpha1-PI kann zur Aktivitätserhöhung der Proteasen und zum Umbau des Kollagengewebes führen. Möglicherweise kommt es zusammen mit einem lokal wirksamen Einflußfaktor schließlich zur dystrophen Kalzifikation. Die humangenetischen Untersuchungen sprechen nicht für eine genetische Determinierung des alpha1-PI-Mangels, sondern legen eine erworbene hepatische Störung nahe.

  19. Why Was General Richard O’Connor’s Command in Northwest Europe Less Effective Than Expected?

    Science.gov (United States)

    2011-03-01

    Commander of 7 Division and Military Governor of Jerusalem , September 1938- August 1939. ______. Papers of General Sir Richard O’Connor KT, GCB, DSO, MC...Montgomery, Brian. A Field Marshall in the Family: A Personal Biography of Montgomery of Alamein. New York: Taplinger, 1973. Montgomery, Field...Commanders: A Composite Biography . Combat Studies Institute publications, Fort Leavenworth, Kansas: U.S. Army Command and General Staff College, 1989

  20. Rekonstruktion mit Netz beim komplexen Prolaps der Frau: Was hilft es der Patientin wirklich?

    Directory of Open Access Journals (Sweden)

    Hierl J

    2010-01-01

    Full Text Available Einleitung: Der komplexe Genitaldeszensus der Frau geht oftmals mit einer deutlichen Einschränkung der Lebensqualität (LQ einher. Dennoch ist der Endpunkt der meisten klinischen Analysen rein anatomischer und funktioneller Natur. In der vorliegenden Untersuchung wurden die Einflüsse der operativen Rekonstruktion mit einem Netz prospektiv auf die LQ evaluiert. Patienten und Methoden: Bei insgesamt 111 Patientinnen mit Deszensus erfolgte zwischen 08/2005 und 12/2007 eine operative Versorgung mittels vaginaler Netzeinlage (anteriorer bzw. kompletter Mesh-Repair. Die LQ wurde prospektiv prä- und postoperativ anhand standardisierter LQ-Fragebögen erfasst. Ergebnisse: Präoperativ zeigte sich bei den Patientinnen eine signifikant reduzierte LQ gegenüber einem Normalkollektiv (p 0,01. Bei 7 % der Patientinnen mit anteriorem, und bei 11 % mit komplettem Mesh-Repair lag postoperativ kein adäquates klinisches Ergebnis vor. In diesem Kollektiv zeigte sich kein signifikanter Unterschied in den LQ-Tests prä- und postoperativ. Bei gutem postoperativem Ergebnis zeigte sich in der Gruppe mit anteriorer Netzeinlage lediglich bei 45 % (p = 0,021, bei kompletter Netzeinlage nur bei 31 % (p = 0,041 eine signifikant verbesserte LQ. Bei kleiner Fallzahl und kurzem Nachbeobachtungszeitraum kann eine gültige Aussage bezüglich der LQ nach Deszensuschirurgie mit Netzeinlage jedoch noch nicht getroffen werden.

  1. Evaluation of the MIT RMID 1000 system for the identification of Listeria species.

    Science.gov (United States)

    Ricardi, John; Haavig, David; Cruz, Lasaunta; Paoli, George; Gehring, Andrew

    2010-01-01

    The Micro Imaging Technology (MIT) 1000 Rapid Microbial Identification (RMID) System is a device that uses the principles of light scattering coupled with proprietary algorithms to identify bacteria after being cultured and placed in a vial of filtered water. This specific method is for pure culture identification of Listeria spp. A total of 81 microorganisms (55 isolates) were tested by the MIT 1000 System, of which 25 were Listeria spp. and 30 a variety of other bacterial species. In addition, a total of 406 tests over seven different ruggedness parameters were tested by the MIT 1000 System to determine its flexibility to the specifications stated in the MIT 1000 System User Guide in areas where they might be deviated by a user to shorten the test cycle. Overall, MIT concluded that the MIT 1000 System had an accuracy performance that should certify this Performance Test Method for the identification of Listeria spp. This report discusses the tests performed, results achieved, and conclusions, along with several reference documents to enable a higher understanding of the technology used by the MIT 1000 System.

  2. Sufi, Christian or Buddhist? Richard Francis Burton’s “Parameters of Belief”

    Directory of Open Access Journals (Sweden)

    John Wallen

    2013-09-01

    Full Text Available Richard Burton has been interpreted and misinterpreted by literary critics as eminent as Edward Said and Louisa Pratt as well as by others such as Rana Kabbani and Reina Lewis. Biographers like Fawn Brody, Edward Rice, Mary Lovell and Jon Godsall have also had their say. Burton has been variously described as imperialist, sexist, gay, obssessed with pornography, racist, plagiarist, sexual libertine, scatologist, expert sociologist, profoundly deceitful and impotent. In spite of this negative press, interest in Burton is always high as his life and times are relevant to many scholars interested in the 19th century origins of modern thought and postcolonial ideas. In this paper presentation I will attempt to get beyond the confused and contradictory portrayals of Burton over the last 50 or so years by looking in some detail at Burton’s two long poems: Stone Talk and The Kasidah. In these works, published 15 years apart, Burton writes under pseudonyms and, as I will argue, is able to express many of his deepest beliefs, especially in The Kasidah where he is playing the part of Hadji Abu Al Yezid, a Sufi like-wise man who possesses some startling similarities to Burton himself. What emerges from this close examination of the texts is a sensitive relativist who, while adhering to the scientific method in all his practical dealings, is yet able to consider the possibility that everything we see around us and all our experience of the world might be, finally, nothing more than Maya and illusion.

  3. The Effect of Richard Wagner's Music and Beliefs on Hitler's Ideology

    Directory of Open Access Journals (Sweden)

    Carolyn S. Ticker

    2016-09-01

    Full Text Available The Holocaust will always be remembered as one of the most horrific and evil events in all of history. One question that has been so pervasive in regards to this historical event is the question of why. Why exactly did Hitler massacre the Jewish people? Why did he come to the conclusion that the Jews were somehow lesser than him, and that it was okay to kill them? What and who were his influences and how did they help form Hitler’s opinions leading up to the Holocaust? Although more than one situation or person influenced Hitler, I believe that one man in particular really helped contribute to Hitler’s ideas, especially about the Jewish people. This man is the famous musician Richard Wagner. While musicologists admit that Wagner was a musical genius, one aspect of his career that is hard to ignore is his strong antisemitism. In addition to speaking about his hatred for the Jews, he also wrote about it in his music, making it hard to glance over. Hitler had been close to the Wagner family, and had an obsessive, cult-like infatuation with Wagner’s music beginning in his childhood. This infatuation with Wagner’s music and his closeness to his later family helped facilitate and solidify his negative views about the Jewish people. In this paper I will explore the antisemitism that is within Wagner’s music and writing, and then I will discuss how Wagner’s antisemitism helped inform, influence, and shape Hitler’s ideas, indirectly assisting in the propagation of the Holocaust.

  4. Visiting Richard Serra’s Promenade sculpture improves postural control and judgment of subjective visual vertical.

    Directory of Open Access Journals (Sweden)

    Zoï eKapoula

    2014-12-01

    Full Text Available Body sway while maintaining an upright quiet stance reflects an active process of balance based on the integration of visual, vestibular, somatosensory and proprioceptive inputs. Richard Serra’s Promenade sculpture featured in the 2008 Monumenta exhibition at the Grand Palais in Paris, France is herein hypothesised to have stimulated the body’s vertical and longitudinal axes as it showcased 5 monumental rectangular solids pitched at a 1.69° angle.Using computerised dynamic posturography we measured the body sway of 23 visitors when fixating a cross, or when observing the artwork (fixating it or actively exploring it with eye movements before and after walking around and alongside the sculpture (i.e., before and after a promenade. A first fixation at the sculpture increased medio-lateral stability (in terms of spectral power of body sway. Eye movement exploration in the depth of the sculpture increased antero-posterior stability (in terms of spectral power and cancelling time of body sway at the expense of medio-lateral stability (in terms of cancelling time. Moreover, a medio-lateral instability associated with eye movement exploration before the promenade (in terms of body sway sensu stricto was cancelled after the promenade. Finally, the overall medio-lateral stability (in terms of spectral power increased after the promenade.Fourteen additional visitors were asked to sit in a dark room and adjust a luminous line to what they considered to be the earth-vertical axis. The promenade executed within the sculpted environment afforded by Serra’s monumental statuary works resulted in significantly improved performances on the subjective visual vertical test.We attribute these effects to the sculpted environment provided by the exhibition which may have acted as a kind of physiologic training ground thereby improving the visitors’ overall sense of visual perspective, equilibrium and gravity.

  5. Staging Unincorporated Power: Richard Harding Davis and the Critique of Imperial News

    Directory of Open Access Journals (Sweden)

    Nirmal Trivedi

    2011-12-01

    Full Text Available This essay contextualizes the work of war correspondent Richard Harding Davis within an evolving “imperial news apparatus” that would culminate in his reporting of the Spanish-American War. Critics have conventionally framed Davis squarely within the imperial cause, associating him with his admirer Roosevelt and naval admiral Alfred T. Mahan. Contrary to readings of Davis as an apologist for US imperialism, Trivedi contends that Davis understood how US imperial power relied on an information apparatus to communicate to an increasingly media-conscious American public through culture, that is, via familiar narratives, symbols, and objects—what Trivedi calls “imperial news.” The essay follows Davis’s development from his fictional representation of the new war correspondent in “The Reporter Who Made Himself King” to his own war correspondence before and after the Spanish-American War as collected in the memoirs A Year from a Reporter’s Notebook (1897, Cuba in War Time (1897, and Notes of a War Correspondent (1912. Davis’s war correspondence and fictional work effectively stage US imperialism as “unincorporated power”: that is, as power reliant on a developing news-making apparatus that deploys particular discursive strategies to validate its political claims. This staging critiques strategies of US imperial sovereignty—specifically its “privatization of knowledge” and its promotion of the war correspondent as nothing more than a spectator and purveyor of massacres.

  6. Charles Darwin, Richard Owen, and Natural Selection: A Question of Priority.

    Science.gov (United States)

    Johnson, Curtis N

    2018-05-03

    No single author presented Darwin with a more difficult question about his priority in discovering natural selection than the British comparative anatomist and paleontologist Richard Owen. Owen was arguably the most influential biologist in Great Britain in Darwin's time. Darwin wanted his approbation for what he believed to be his own theory of natural selection. Unfortunately for Darwin, when Owen first commented in publication about Darwin's theory of descent he was openly hostile (Edinb. Rev. vol. 111, Article VIII, 1860, pp. 487-533, anonymous). Darwin was taken off-guard. In private meetings and correspondence prior to 1860 Owen had been nothing but polite and friendly, even helping Darwin in cataloguing and analyzing Darwin's zoological specimens from the Beagle voyage. Every early indication predicted a life-long friendship and collaboration. But that was not to be. Owen followed his slashing review with a mounting campaign in the 1860s to denounce and discredit both Darwin and his small but ascendant circle of friends and supporters. But that was not enough for Owen. Starting in 1866, perhaps by now realizing Darwin had landed the big fish, Owen launched a new campaign, to claim the discovery of "Darwin's theory" for himself. Darwin naturally fought back, mainly in the "Historical Sketch" that he prefaced to Origin starting in 1861. But when we peel back the layers of personal animus and escalating vituperation we discover in fact their quarrel was generated more by mutual misunderstanding than scientific disagreement. The battle ended only when Darwin finally penetrated to the crux of the matter and put an end to the rivalry in 1872, in the final version of the Sketch.

  7. Morrow, Reiff, Receive 2013 Space Physics and Aeronomy Richard Carrington Awards: Response

    Science.gov (United States)

    Reiff, Patricia H.

    2014-08-01

    It is a special privilege to receive this award honoring Richard Carrington's discovery of what we now call space weather. It is particularly appropriate that this award also recognizes Cherilynn Morrow, who 20 years ago made a presentation to the Space Science Advisory Committee on Jeff Rosendhal's idea of mission-based E/PO. We worked together, bringing that idea to the successful, but threatened, network it is today. For me, learning and teaching go hand in hand—as we publish our findings for our peers, we should also repay the public investment in our research with accurate, understandable results. My interest in space science was sparked by a father-daughter course in astronomy sponsored by the Brownies at the Oklahoma City Planetarium and kindled by the Bell Labs production The Strange Case of the Cosmic Rays directed by Frank Capra. Knowing that planetarium shows and educational movies can change lives, I have devoted a large portion of my last 25 years to creating software, shows, and portable planetariums to inspire and engage youth. This has not been a one-person effort, of course. My work Cherilynn Ann Morrow would have been impossible without the collaboration of Carolyn Sumners, vice president of the Houston Museum of Natural Science. Our museum kiosk and planetarium control software would not have happened without the skill and perseverance of my chief programmer, Colin Law. Jim Burch has been first a mentor and then a colleague on both the research and outreach sides of my career. I share this honor with a long line of highly talented students and postdocs who have contributed science content and outreach efforts. Most importantly, without the support of my husband, Tom Hill, I would not have had the time and freedom to build an educational network while continuing research and raising a family. I thank AGU for bestowing this honor.

  8. The reliability of the German version of the Richards Campbell Sleep Questionnaire.

    Science.gov (United States)

    Krotsetis, Susanne; Richards, Kathy C; Behncke, Anja; Köpke, Sascha

    2017-07-01

    The assessment of sleep quality in critically ill patients is a relevant factor of high-quality care. Despite the fact that sleep disturbances and insufficient sleep management contain an increased risk of severe morbidity for these patients, a translated and applicable instrument to evaluate sleep is not available for German-speaking intensive care settings. This study aimed to translate the Richards Campbell Sleep Questionnaire (RCSQ), a simple and validated instrument eligible for measuring sleep quality in critically ill patients, and subsequently to evaluate the internal consistency of the German version of the RCSQ. Furthermore, it also aimed to inquire into the perception of sleep in a sample of critically ill patients. The RCSQ was translated following established methodological standards. Data were collected cross-sectionally in a sample of 51 patients at 3 intensive care units at a university hospital in Germany. The German version of the RCSQ showed an overall internal consistency (Cronbach's alpha) of 0·88. The mean of the RSCQ in the sample was 47·00 (SD ± 27·57). Depth of sleep was rated the lowest and falling asleep again the highest of the RCSQ sleep items. The study demonstrated very good internal consistency of the German version of the RCSQ, allowing for its application in practice and research in German-speaking countries. Quality of sleep perception was generally low in this sample, emphasizing the need for enhanced care concepts regarding the sleep management of critically ill patients. Relevance to clinical practice Assessment of self-perception of sleep is crucial in order to plan an individually tailored care process. © 2017 British Association of Critical Care Nurses.

  9. An Enlightenment proposal for music therapy: Richard Brocklesby on music, spirit, and the passions.

    Science.gov (United States)

    Gouk, Penelope

    2015-01-01

    In 1749, the London physician Richard Brocklesby (1722-1797) published his Reflections on Antient [sic] and Modern Musick, an essay that not only sought to compare these practices in terms of their effects, but also to gather evidence supporting the use of music in treating mania and other mental diseases. As might be expected, Brocklesby's discussion of music therapy has already received attention by authors looking back to the origins of this practice, not least because he offers an account of a successful musical cure that took place in his own time (Rorke, 2001). My chapter, however, seeks to broaden the discussion of the Reflections, in order to show how Brocklesby's projected musical cures fit into his larger worldview, one that was influenced as much by Plato and other ancient philosophers as it was by modern thinkers such as Isaac Newton and his followers. Brocklesby's argument was essentially that music acted as a link between the mind and body and therefore could restore their intrinsic harmony, a connection that was mediated by the animal spirits, which also served as the vehicle of the passions. The movements and proportions of music could arouse or quell the passions by their effect on these (imaginary) spirits, which flowed through the nerves and brain and acted as the agent for the mind or soul. I show how his account of music in antiquity led him to reflect on the way that music was perceived and responded to in his own time, both as a stimulus to mental and bodily action, and as a source of esthetic pleasure through the cultivation of musical taste. © 2015 Elsevier B.V. All rights reserved.

  10. An experimental 'Life' for an experimental life: Richard Waller's biography of Robert Hooke (1705).

    Science.gov (United States)

    Moxham, Noah

    2016-03-01

    Richard Waller's 'Life of Dr Robert Hooke', prefixed to his edition of Hooke's Posthumous Works (1705), is an important source for the life of one of the most eminent members of the early Royal Society. It also has the distinction of being one of the earliest biographies of a man of science to be published in English. I argue that it is in fact the first biography to embrace the subject's natural-philosophical work as the centre of his life, and I investigate Waller's reasons for adopting this strategy and his struggle with the problem of how to represent an early experimental philosopher in print. I suggest that Waller eschews the 'Christian philosopher' tradition of contemporary biography - partly because of the unusually diverse and fragmentary nature of Hooke's intellectual output - and draws instead upon the structure of the Royal Society's archive as a means of organizing and understanding Hooke's life. The most quoted phrase from Waller's biography is that Hooke became 'to a crime close and reserved' in later life; this essay argues that Waller's biographical sketch was fashioned in order to undo the effects of that reserve. In modelling his approach very closely on the structure of the society's records he was principally concerned with making Hooke's work and biography accessible, intelligible and useful to the fellowship in a context familiar to them, a context which had provided the institutional framework for most of Hooke's adult life. I argue that Waller's 'Life' was also intended to make the largest claims for Hooke's intellectual standing that the author dared in the context of the enmity between Hooke and Isaac Newton once the latter became president of the Royal Society. However, I also adduce fresh manuscript evidence that Waller actually compiled, but did not publish, a defence of Hooke's claim to have discovered the inverse square law of gravity, allowing us to glimpse a much more assertive biography of Hooke than the published version.

  11. Timothy Leary, Richard Alpert (Ram Dass) and the changing definition of psilocybin.

    Science.gov (United States)

    Wark, Colin; Galliher, John F

    2010-05-01

    This research focuses on the events leading to the 1968 U.S. federal prohibition of psilocybin. It is a study of duelling moral entrepreneurs-Timothy Leary and Richard Alpert vs. the Harvard University Administration. The goal is to show how the primary active compound in an ostensibly harmless fungus (the psilocybin mushroom) became controversial in less than a decade. We used books, newspapers, magazine articles and previously unpublished materials (including documents from the Harvard Archives) to analyze Leary and Alpert's lives and careers through the early 1970s. The prohibition of psilocybin in the U.S. was largely a product of Leary and Alpert's involvement in the "Harvard drug scandal" and their transformation from Harvard professors to countercultural icons. They tested the substance on a variety of human subjects and in doing so piqued the interest of Harvard undergraduates while drawing condemnation from other faculty and Harvard administrators. This case is theoretically interesting because unlike most illegal drugs, psilocybin was never linked to a threatening minority group, but to some of the nation's most privileged youth. The Harvard administrators were not really moral entrepreneurs but Leary and Alpert clearly were. Although they were far from being prohibitionists, they were self-righteous crusaders on different but equally holy missions for the good of young and minority Americans. Ironically, due to their successes the possession of psilocybin was criminalized under United States federal law in 1968 (Pub. L. No. 90-639, Stat. 1361 1968 and Boire, 2002). This case study demonstrates that crusaders can be successful in changing culture even when laws are passed in futile attempts to control their behaviour, just as Leary predicted. Copyright 2009 Elsevier B.V. All rights reserved.

  12. Richard Doll and Alice Stewart: reputation and the shaping of scientific "truth".

    Science.gov (United States)

    Greene, Gayle

    2011-01-01

    As the world watched the Fukushima reactors release radionuclides into the ocean and atmosphere, the warnings of Dr. Alice Stewart about radiation risk and the reassurances of Sir Richard Doll assumed renewed relevance. Doll and Stewart, pioneer cancer epidemiologists who made major contributions in the 1950s-he by demonstrating the link between lung cancer and smoking, she by discovering that fetal X-rays double the chance of a childhood cancer-were locked into opposition about low-dose radiation risk. When she went public with the discovery that radiation at a fraction of the dose "known" to be dangerous could kill a child, her reputation plummeted, whereas Doll, foremost among her detractors, was knighted and lauded as "the world's most distinguished medical epidemiologist" for his work. Their lives and careers, so closely intertwined, took contrary courses, he becoming "more of the establishment" (as he said), while she became more oppositional. When it was discovered, after his death, that he'd been taking large sums of money from industries whose chemicals he was clearing of cancer risk, his reputation remained unscathed; it is now enshrined in the "Authorized Biography" (2009) commissioned by the Wellcome Institute, along with Doll's denigration of Stewart as an "embittered" woman and biased scientist. Stewart lived long enough to see radiation science move her way, to see international committees affirm, in the 1990s, that there is no threshold beneath which radiation ceases to be dangerous; recent evidence from Chernobyl is bearing out her warnings. But a look at the making and breaking of these reputations reveals the power of status, position, and image to shape scientific "knowledge" and social policy.

  13. Gebrauch von Komplementärmedizin bei Patienten mit metastasierendem Melanom unter Therapie mit Ipilimumab innerhalb einer klinischen Studie.

    Science.gov (United States)

    Huebner, Jutta; Mohr, Peter; Simon, Jan-Christoph; Fluck, Michael; Berking, Carola; Zimmer, Lisa; Loquai, Carmen

    2016-05-01

    In Deutschland wenden 40-90 % aller Krebspatienten Methoden der komplementären and alternativen Medizin (KAM) an. Bis dato gibt es kein Datenmaterial zum Einsatz der KAM bei Melanompatienten. Das Ziel unserer Studie war es, Daten über den Gebrauch, die Informationsquellen und Ziele von Patienten mit metastasierendem Melanom zu erfassen. Einhundertsechsundfünfzig Patienten aus 25 Studienzentren nahmen an der DecOG-MM-PAL Multibasket Studie teil. Die beteiligten Personen wurden auch gebeten, an einer Nebenstudie teilzunehmen, die ihren Gebrauch von KAM erfassen sollte. Dazu wurde während der Behandlung ein standardisierter Fragebogen zu genau festgelegten Zeitpunkten ausgeteilt. Insgesamt gingen 55 Fragebögen von 32 (21 %) Melanompatienten ein. Von diesen gaben 17 (53 %) ein Interesse an KAM an, und sieben (22 %) machten von KAM Gebrauch. Die Hauptinformationsquellen (31 %) waren Familienmitglieder und Freunde, gefolgt von Ärzten (19 %). Die Hauptgründe für die Anwendung von KAM waren die Stärkung des Immunsystems (41 %) und des Körpers (34 %). Nahrungsergänzungsmittel (Vitamine und Spurenelemente) wurden am häufigsten angewendet (28 %). Eine relativ hohe Anzahl an Patienten mit metastasierendem Melanom machte trotz Teilnahme an einer klinischen Studie von KAM Gebrauch. Wechselwirkungen könnten durch biologisch basierte KAM auftreten, und hier besonders bei immunmodulierenden KAM- Strategien. Um Risiken zu vermeiden, sollte die Kommunikation zwischen den Ärzten und den Patienten verbessert werden. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  14. Skiing and snowboarding center at Bottrop; Mit Ski oder Snowboard runter von der Halde

    Energy Technology Data Exchange (ETDEWEB)

    Matthesius, M. [Lenze GmbH und Co KG, Hameln (Germany)

    2001-09-01

    The 'Alpincenter' at Bottrop is the biggest indoor winter sports center of the world. Its ventilation systems were equipped with specially selected frequency inverters. [German] Skifahren im Hochsommer? Mit dem Snowboard im Ruhrgebiet den Hang hinunter? Beste Wintersportverhaeltnisse an 365 Tagen im Jahr? Und das in Deutschland? Kein Problem. Seit Anfang des Jahres kommen in Bottrop Wintersportfreunde voll auf ihre Kosten. Nach einem halben Jahr Bauzeit hat das Alpincenter seine Pforten geoeffnet. Die Wintersporthalle ist die laengste Anlage auf der Welt. Die gesamte Belueftung wurde mit speziell auf die Klimatechnik (mit Drehzahl geregelten Ventilatoren) abgestimmten Frequenzumrichtern ausgeruestet. (orig./AKF)

  15. Exact and grid-free solutions to the Lighthill-Whitham-Richards traffic flow model with bounded acceleration for a class of fundamental diagrams

    KAUST Repository

    Qiu, Shanwen; Abdelaziz, Mohamed Ewis; Abdel Latif, Fadl Hicham Fadl; Claudel, Christian G.

    2013-01-01

    In this article, we propose a new exact and grid-free numerical scheme for computing solutions associated with an hybrid traffic flow model based on the Lighthill-Whitham-Richards (LWR) partial differential equation, for a class of fundamental

  16. Süüme sundis vabrikujuhti palgatööliseks jääma / Richard Mutso ; interv. Jüri Saar

    Index Scriptorium Estoniae

    Mutso, Richard, 1933-

    2003-01-01

    Intervjuu Võru mööblitehase Wermo peadirektorina töötanud, praeguse tehase nõukogu liikme Richard Mutsoga tehase juhtimisest, euroreferendumist, eraelust. Kommenteerivad: Silva Mutso, Veljo Ipits

  17. Justiça e sociedade liberal em Richard Rorty: justiça como lealdade e o projeto social de uma utopia

    Directory of Open Access Journals (Sweden)

    Marcelo de Almeida Silva

    2014-07-01

    Full Text Available O presente texto pretende explorar o conceito de justiça de Richard Rorty e a proposta da Utopia Liberal que o autor apresenta. Para tanto, explora, dentro da obra de Richard Rorty e de alguns autores com quem dialoga, contribuições para o debate da concepção do termo Justiça como um senso de lealdade ampliada e de sua proposta para uma sociedade mais justa, igualitária e inclusiva.   Abstract: This paper aims to explore the concept of justice from Richard Rorty and his proposal about the idea of a Liberal Utopia. With this goal we seek, within the work of Richard Rorty, and some authors with whom he converses, contributions to the discussion of the conception of justice as an expanded sense of loyalty and his proposal for a fairer, equitable and inclusive society.   Resumen: Este trabajo se propone explorar el concepto de justicia de Richard Rorty y la propuesta de liberal utopía que el autor presenta. Con este objetivo, vamos a buscar en la obra de Richard Rorty, y algunos autores con los que conversa, contribuciones a la discusión sobre la concepción de la justicia como un sentido más amplio de la lealtad y su propuesta de una sociedad más justa, equitativa e incluyente.

  18. MIT/Draper Technology Development Partnership Project: Systems Analysis and On-Station Propulsion Subsystem Design

    National Research Council Canada - National Science Library

    Conklin, Theodore

    1998-01-01

    The objective of this thesis is to describe the process for, and the overall design that resulted from the MIT/Draper Project from August, 1996 to May, 1997, including the specific design of the on...

  19. Entwicklung und Anwendung neuer NMR-Methoden: Orientierungsmedien zur Strukturbestimmung mit anisotropen Parametern und Metabonomics

    OpenAIRE

    Büchler, Silke

    2014-01-01

    Das Ziel dieser Arbeit war die Entwicklung und Anwendung neuer Orientierungsmedien zur Strukturbestimmung mit anisotropen Parametern, sowie die Etablierung von Metabonomics-Studien an Flüssigzellkulturen und Reispflanzen.

  20. Ernährungszustand bei Patienten mit chronisch entzündlichen Darmerkrankungen

    OpenAIRE

    Blunk, Christine

    2009-01-01

    Zahlreiche internationale Studien konnten den negativen Einfluss einer bestehenden Malnutrition auf den Verlauf einer Erkrankung belegen. Dies gilt insbesondere für Patienten mit chronisch entzündlichen Darmerkrankungen wie Morbus Crohn und Colitis ulcerosa, die wie klinische Studien gezeigt haben besonders häufig unter einer Malnutrition leiden. In der vorliegenden Studie wurde der Ernährungszustand von 127 Patienten mit chronisch entzündlichen Darmerkrankungen anhand verschiedener etabli...

  1. "Drugwatch": Forschung mit Schlüsselprofessionellen und illegalen Drogenusern zur Identifikation von Drogentrends

    OpenAIRE

    Mason, Mark; Baker, Oswin; Hardy, Rebecca

    2007-01-01

    Die revidierte "United Kingdom Anti-Drugs Strategy" hat Lücken im Wissen über Drogen verdeutlicht: Insbesondere die Dynamiken, die mit der Entstehung regionalen Drogentrends einhergehen, erwiesen sich trotz mehrjährigem Bemühen als schwer fassbar, und einige hierzu in Großbritannien durchgeführte Studien waren mit erheblichen Problemen behaftet. Deshalb wurde vom "Drugs Analysis and Research Programme" und von "Market and Opinion Research International" (MORI) ein nationales Entwicklungsproje...

  2. Advanced modularity design for the MIT pebble bed reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kadak, Andrew C. [Department of Nuclear Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, 24-202 Cambridge, MA 02139-4307 (United States)]. E-mail: kadak@mit.edu; Berte, Marc V. [Department of Nuclear Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, 24-202 Cambridge, MA 02139-4307 (United States)]. E-mail: mvberte@yahoo.com

    2006-03-15

    The future of all reactors will depend on whether they can be economically built and operated. One of the major impediments to new nuclear construction is the capital cost due in large part to the length of construction time and complexity of the plant. Pebble bed reactors offer the opportunity to reduce the complexity of the plant because the number of safety systems required is significantly reduced due to the inherent safety of the technology. However, because of its small size, the capital cost per kilowatt is likely to be large if traditional construction approaches are followed. This strongly suggests the need for innovative construction concepts to reduce the construction time and cost. MIT has proposed a modularity approach in which the plant is pre-built in space-frame type modules which are built in factories. These space frames would contain all the equipment contained in a given volume. Once equipment in the space frame is installed, the space frame would then be shipped to the site and assembled 'lego-style.' Studies presently underway have demonstrated the feasibility of the concept. Thermal stress analysis has been performed and an integrated design with the space frames has been developed. It is expected that this modularity approach will significantly shorten construction time and expense. This paper proposes a concept for further development, not a final design for the entire plant.

  3. Advanced modularity design for the MIT pebble bed reactor

    International Nuclear Information System (INIS)

    Kadak, Andrew C.; Berte, Marc V.

    2006-01-01

    The future of all reactors will depend on whether they can be economically built and operated. One of the major impediments to new nuclear construction is the capital cost due in large part to the length of construction time and complexity of the plant. Pebble bed reactors offer the opportunity to reduce the complexity of the plant because the number of safety systems required is significantly reduced due to the inherent safety of the technology. However, because of its small size, the capital cost per kilowatt is likely to be large if traditional construction approaches are followed. This strongly suggests the need for innovative construction concepts to reduce the construction time and cost. MIT has proposed a modularity approach in which the plant is pre-built in space-frame type modules which are built in factories. These space frames would contain all the equipment contained in a given volume. Once equipment in the space frame is installed, the space frame would then be shipped to the site and assembled 'lego-style.' Studies presently underway have demonstrated the feasibility of the concept. Thermal stress analysis has been performed and an integrated design with the space frames has been developed. It is expected that this modularity approach will significantly shorten construction time and expense. This paper proposes a concept for further development, not a final design for the entire plant

  4. Lessons learned from the MIT Tara control and data system

    International Nuclear Information System (INIS)

    Gaudreau, M.P.J.; Sullivan, J.D.; Fredian, T.W.; Irby, J.H.; Karcher, C.A.; Rameriz, R.A.; Sevillano, E.; Stillerman, J.A.; Thomas, P.

    1987-10-01

    The control and data system of the MIT Tara Tandem Mirror has worked successfully throughout the lifetime of the experiment (1983 through 1987). As the Tara project winds down, it is appropriate to summarize the lessons learned from the implementation and operation of the control and data system over the years and in its final form. The control system handled ∼2400 I/0 points in real time throughout the 5 to 10 minute shot cycle while the data system, in near real time, handled ∼1000 signals with a total of 5 to 7 Mbytes of data each shot. The implementation depended upon a consistent approach based on separating physics and engineering functions and on detailed functional diagrams with narrowly defined cross communication. This paper is a comprehensive treatment of the principal successes, residual problems, and dilemmas that arose from the beginning until the final hardware and software implementation. Suggestions for future systems of either similar size or of larger scale such as CIT are made in the conclusion. 11 refs., 1 fig

  5. The effects of coal dust on photosynthetic performance of the mangrove, Avicennia marina in Richards Bay, South Africa

    International Nuclear Information System (INIS)

    Naidoo, G.; Chirkoot, D.

    2004-01-01

    Richards Bay, on the northern KwaZulu-Natal coast, is the largest coal exporting port in South Africa. The coal is stored at the Richards Bay Coal Terminal (RBCT) prior to export. Dust from coal operations is a major problem in the Richards Bay area. In this study, we tested the hypothesis that coal dust adversely affects photosynthetic performance of Avicennia marina (Forssk.) Vierh., the dominant mangrove species in the harbour. Photosynthetic performance was determined on 10 trees by measuring carbon dioxide uptake and chlorophyll fluorescence parameters at two elevation sites and on upper and lower leaf surfaces that were covered or uncovered with coal dust. Measurements were made on five clear, sunny days at saturating light (>1000 μmol m -2 s -1 ) and high temperature (28-30 deg. C). Coal dust significantly reduced carbon dioxide exchange of upper and lower leaf surfaces by 17-39%, the reduction being generally greater on the lower leaf surface that is covered by a dense mat of trichomes and salt glands. The reduction in carbon dioxide exchange by coal dust was higher at the high elevation site that supported isolated dwarfed trees. The chlorophyll fluorescence data indicated that leaves coated with dust exhibited significantly lower photosystem II (PS II) quantum yield, lower electron transport rate (ETR) through PSII and reduced quantum efficiency of PSII (F v F m ). The chlorophyll fluorescence data supported the gas exchange measurements and are consistent with reduced photosynthetic performance of leaves coated with coal dust. - Coal dust reduced photosynthetic performance of the mangrove, Avicennia marina

  6. O ateísmo de Richard Dawkins nas fronteiras da ciência evolucionista e do senso comum

    OpenAIRE

    Franco, Clarissa de

    2014-01-01

    O objeto de estudo consiste nas principais ideias ateístas de Richard Dawkins e na recepção destas por parte dos ateus inseridos na cultura brasileira. Dawkins é um dos principais divulgadores e militantes do movimento ateísta da atualidade, e a despeito de sua faceta pública divulgada em sites mundiais e em livros de reconhecido sucesso existem debates do autor, concernentes aos espaços acadêmicos e restritos a cientistas, que nem sempre se apresentam congruentes às suas e...

  7. Genetics and the origin of species: the continuing synthesis a symposium in honor of Richard G. Harrison

    Science.gov (United States)

    Grosberg, Richard K.; Rand, David M.; Normark, Benjamin B.

    2013-01-01

    This is a special issue of Genetica that has its origins in a symposium held in honor of Richard G. Harrison at Ithaca, New York on July 22–23. Former students of Rick Harrison organized the symposium and most of the speakers were former students, as well. The quality and breadth of the talks were a testament to Rick’s influence as a thinker, synthesizer, and mentor and it is only appropriate to reflect on Rick’s contributions to the fields of evolutionary ecology, systematics, and genetics in this preface to the symposium articles. PMID:21152955

  8. Erste Erfahrungen mit RDA an wissenschaftlichen Universalbibliotheken in Deutschland - Ergebnisse aus Fokusgruppengesprächen mit Katalogisierenden

    Directory of Open Access Journals (Sweden)

    Heidrun Wiesenmüller

    2017-04-01

    Full Text Available Einige Monate nach dem Umstieg auf das neue Regelwerk "Resource Description and Access" (RDA wurden an 18 großen deutschen wissenschaftlichen Universalbibliotheken Fokusgruppengespräche mit Katalogisierererinnen und Katalogisierern durchgeführt. Die Katalogisierenden wurden u.a. befragt, wie sicher sie sich bei der Anwendung von RDA fühlen, was sie am neuen Regelwerk gut oder schlecht finden, wie sie den Aufwand im Vergleich zum früheren Regelwerk RAK einschätzen, welche Informations- und Hilfsmittel sie verwenden und wie sie zu den regelmäßigen Änderungen im Standard stehen. Der vorliegende Aufsatz dokumentiert die Ergebnisse der Gespräche.   Several months after the introduction of the new cataloging standard "Resource Description and Access" (RDA, focus-group interviews with catalogers were conducted at 18 large academic and state libraries in Germany. Among other things, the catalogers were asked how confident they feel in applying RDA, which aspects of the new cataloging code they like or do not like, how they estimate the expenditure of time in comparison to the former cataloging code RAK, which sources they use to get help or information, and what they think about the frequent changes to the new standard. The paper presents the results of these interviews.

  9. Knocking down mitochondrial iron transporter (MIT) reprograms primary and secondary metabolism in rice plants.

    Science.gov (United States)

    Vigani, Gianpiero; Bashir, Khurram; Ishimaru, Yasuhiro; Lehmann, Martin; Casiraghi, Fabio Marco; Nakanishi, Hiromi; Seki, Motoaki; Geigenberger, Peter; Zocchi, Graziano; Nishizawa, Naoko K

    2016-03-01

    Iron (Fe) is an essential micronutrient for plant growth and development, and its reduced bioavailability strongly impairs mitochondrial functionality. In this work, the metabolic adjustment in the rice (Oryza sativa) mitochondrial Fe transporter knockdown mutant (mit-2) was analysed. Biochemical characterization of purified mitochondria from rice roots showed alteration in the respiratory chain of mit-2 compared with wild-type (WT) plants. In particular, proteins belonging to the type II alternative NAD(P)H dehydrogenases accumulated strongly in mit-2 plants, indicating that alternative pathways were activated to keep the respiratory chain working. Additionally, large-scale changes in the transcriptome and metabolome were observed in mit-2 rice plants. In particular, a strong alteration (up-/down-regulation) in the expression of genes encoding enzymes of both primary and secondary metabolism was found in mutant plants. This was reflected by changes in the metabolic profiles in both roots and shoots of mit-2 plants. Significant alterations in the levels of amino acids belonging to the aspartic acid-related pathways (aspartic acid, lysine, and threonine in roots, and aspartic acid and ornithine in shoots) were found that are strictly connected to the Krebs cycle. Furthermore, some metabolites (e.g. pyruvic acid, fumaric acid, ornithine, and oligosaccharides of the raffinose family) accumulated only in the shoot of mit-2 plants, indicating possible hypoxic responses. These findings suggest that the induction of local Fe deficiency in the mitochondrial compartment of mit-2 plants differentially affects the transcript as well as the metabolic profiles in root and shoot tissues. © The Author 2015. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  10. Spin-dependent Nucleon Structure Studies at MIT/Bates

    International Nuclear Information System (INIS)

    Botto, T.

    2005-01-01

    We present preliminary results from recent measurements of the proton, neutron and deuterium electro-magnetic form factors obtained by the BLAST collaboration at the MIT/Bates Linear Accelerator Facility. BLAST (Bates Large Acceptance Spectrometer Toroid) is a large-acceptance multi-purpose detector dedicated to studies of exclusive spin-dependent electron scattering from internal polarized targets. BLAST makes use of stored electron beam currents in excess of 150 mA with a 60-70% polarization. The electron beam is let through a 15 mm diameter, 60 cm long open-ended storage cell which is fed with ultra-pure, high-polarization H1,D1 gas from an Atomic Beam Source. The target polarization can be rapidly reversed between different vector and tensor target states, thus minimizing systematic uncertainties. The target spin can be oriented to any in-plane direction via a set of Helmholtz coils. Target polarizations in the storage cell of up to 80% (vector) and 70% (tensor) have been routinely achieved over a period of several months. Our data on the D-vector(e-vector,e'n) reaction off vector polarized deuterium allow for a unique extraction of the neutron charge form factor G E n . At same time, complementary measurements of G M n , T20 and the spin-dependent nucleon momentum distributions in deuterium are obtained via the D-vector(e-vector,e'), D (e-vector,e'd) and D (e-vector,e'p) reactions. In addition, BLAST data on vector polarized hydrogen will provide novel measurements of the GE/GM form-factor ratio on the proton as well as of the spin-dependent electro-excitation of the Δ(1232) resonance. Such comprehensive program on few body physics is now well underway and preliminary data will be presented

  11. Verantwortlicher Umgang mit Antibiotika: Notwendigkeit der Antibiotikareduktion in der Aknetherapie.

    Science.gov (United States)

    Gollnick, Harald P M; Buer, Jan; Beissert, Stefan; Sunderkätter, Cord

    2016-12-01

    Der übermäßige oder unkritische weltweite Einsatz von Antibiotika in der Medizin hat die Ausbreitung von Antibiotikaresistenzen beschleunigt. In einigen Bereichen sind viele Antibiotika bei bakteriellen Infektionen, die zuvor noch gut auf antibakterielle Wirkstoffe reagierten, mittlerweile wirkungslos geworden. Dermatologen/Venerologen setzten orale und topische Antibiotika bei der Behandlung von Acne vulgaris routinemäßig ein, obwohl Akne weder eine infektiöse Erkrankung ist noch alleine durch das Propionibacterium getriggert wird. Vielmehr ist sie eine komplexe, chronische entzündliche Hauterkrankung, die durch verschiedene pathogenetische Faktoren wie follikuläre Hyperkeratose, erhöhter Sebumproduktion, bakterielle Proliferation und Entzündung zustande kommt. Folglich sollte eine erfolgreiche Therapie auf die Bekämpfung verschiedener pathogenetischer Faktoren und nicht nur auf die von Propionibacterium acnes abzielen. Daher wurden topische Retinoide und Benzoylperoxid als Mittel der ersten Wahl definiert. Monotherapien mit lokalen Antibiotika sollten insgesamt vermieden werden. Systemische Antibiotika der Tetrazyklin-Gruppe haben bei bestimmen Krankheitsstadien ihren Sinn, ihre Wirkung könnte aber eher auf der antientzündlichen als auf der antibiotischen Reaktion beruhen. Gesundheitsbehörden ermahnen alle Gesundheitsdienstleister, den Einsatz von Antibiotika einzuschränken. Das Nutzen-Risiko-Verhältnis muss bei der Entscheidung für oder gegen eine antibiotische Therapie bei einem einzelnen Patienten immer auch in Bezug auf das öffentliche Interesse am Erhalt der Wirksamkeit von Antibiotika abgewogen werden. Im Folgenden werden das aktuelle Krankheitskonzept zu Acne vulgaris und die sich daraus ableitenden Konsequenzen für den Einsatz von Antibiotika vorgestellt. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  12. Mit Bourdieu in die Stadt: Relevanz, Prinzipien, Anwendungen

    Directory of Open Access Journals (Sweden)

    Loïc Wacquant

    2017-06-01

    Full Text Available Dieser Beitrag zeigt die Relevanz der Soziologie Bourdieus für die Stadtforschung auf, indem er Bourdieus Frühwerk zu Macht, Raum und Urbanisierung im Béarn und Algerien aufgreift und es mit seinem Spätwerk verknüpft, in welchem er das soziale Leiden in der französischen Metropole analysiert. Es wirft ein Schlaglicht auf die vier übergreifenden Prinzipien, die Bourdieus Forschungspraxis antreiben und eine fruchtbare Anleitung für die Stadtforschung sein können: den Bachelardschen Imperativ des erkenntnistheoretischen Bruchs und der erkenntnistheoretischen Wachsamkeit; die Webersche Aufforderung zur dreifachen Historisierung des Handelnden (Habitus, der Welt (sozialer Raum, wovon das soziale Feld lediglich einen Untertypus darstellt und der Kategorien des Analytikers (erkenntnistheoretische Reflexivität; den Leibnizschen-Durkheimschen Vorschlag, eine topologische Denkweise zu nutzen, um den Wechselbeziehungen zwischen symbolischem, sozialem und physischem Raum nachzuspüren; sowie das Cassirersche Moment, das uns dazu anhält, die konstitutive Wirksamkeit symbolischer Strukturen zur Kenntnis zu nehmen. Ich möchte zudem auf drei Fallstricke hinweisen, die eine Stadtforschung auf den Spuren Bourdieus tunlichst vermeiden sollte: die Fetischisierung von Konzepten; die Verlockung, sich der Sprache Bourdieus zu bedienen („speaking Bourdieuse“, ohne die Forschungsschritte, die die Bourdieuschen Begriffe verlangen, tatsächlich durchzuführen; sowie das zwanghafte Überstülpen seines Theorierahmens als Ganzes auch in Fällen, in denen es produktiver wäre, einzelne Bausteine zu übertragen.

  13. Undergraduate Research and Education at MIT Haystack Observatory

    Science.gov (United States)

    Pratap, P.; Salah, J.

    2000-05-01

    The MIT Haystack Observatory Undergraduate Research Initiative is an NSF- funded program aimed at involving undergraduate students in active radio astronomical research. The project has two major thrusts - students get hands-on experience using a small radio telescope that has been developed at Haystack and which will be provided as a low cost kit early next year. Beta versions of this telescope are being built for a select group of institutions. The second component is a research experience with the Haystack 37-m telescope. Use of the 37-m telescope has ranged from classroom demonstrations to original research projects. The Small Radio Telescope (SRT) project consists of a 2m dish with a 1420 MHz receiver. The antenna has a two axis mount that provides full sky coverage. The telescope is intended to provide students and faculty with an introduction to radio astronomy and instrument calibration. Observations of the sun and the galactic HI line are possible with the current version of this telescope. The 37-m telescope program is aimed at providing students with a research experience that can result in publishable results. The telescope has also been used in providing students with an introduction to the scope of radio astronomical data including continuum and spectral line observations. Classroom demonstrations have also been tested with non-science majors. Extensive supporting materials for the project have been developed on the world wide web. These include a radio astronomy tutorial, hardware and software information about both telescopes and project descriptions. We also provide curriculum suggestions to aid faculty incorporate radio astronomy into their courses.

  14. Die Wirkung von Desacetylcefotaxin, einem Metaboliten von Cefotaxim, in vitro und auf die experimentelle Infektion mit Escherichia coli

    OpenAIRE

    Wirbelauer, J.; Hof, H.; Hacker, Jörg

    2009-01-01

    Die MHK-Werte von Desacetylcefotaxim gegen verschiedene, z. T. ampicillinresistente Stämme von Escherichia coH, die mit Hilfe einer Agardilutionsmethode erhoben wurden, waren höher als die von Cefotaxim und Ceftriaxon, jedoch niedriger als die von Cefoxitin. In einem Modell der systemischen Infektion der Maus mit einem plasmidtragenden, betalactamaseproduzierenden Stamm von E. coli führte die Therapie mit Desacetylcefotaxim zu einer starken Reduktion der Keime pro Leber. Im Vergleich zur Ther...

  15. The ISS flight of Richard Garriott: a template for medicine and science investigation on future spaceflight participant missions.

    Science.gov (United States)

    Jennings, Richard T; Garriott, Owen K; Bogomolov, Valery V; Pochuev, Vladimir I; Morgun, Valery V; Garriott, Richard A

    2010-02-01

    A total of eight commercial spaceflight participants have launched to the International Space Station (ISS) on Soyuz vehicles. Based on an older mean age compared to career astronauts and an increased prevalence of medical conditions, spaceflight participants have provided the opportunity to learn about the effect of space travel on crewmembers with medical problems. The 12-d Soyuz TMA-13/12 ISS flight of spaceflight participant Richard Garriott included medical factors that required preflight intervention, risk mitigation strategies, and provided the opportunity for medical study on-orbit. Equally important, Mr. Garriott conducted extensive medical, scientific, and educational payload operations during the flight. These included 7 medical experiments and a total of 15 scientific projects such as protein crystal growth, Earth observations/photography, educational projects with schools, and amateur radio. The medical studies included the effect of microgravity on immune function, sleep, bone loss, corneal refractive surgery, low back pain, motion perception, and intraocular pressure. The overall mission success resulted from non-bureaucratic agility in mission planning, cooperation with investigators from NASA, ISS, International Partners, and the Korean Aerospace Research Institute, in-flight support and leadership from a team with spaceflight and Capcom experience, and overall mission support from the ISS program. This article focuses on science opportunities that suborbital and orbital spaceflight participant flights offer and suggests that the science program on Richard Garriott's flight be considered a model for future orbital and suborbital missions. The medical challenges are presented in a companion article.

  16. Mit1 Transcription Factor Mediates Methanol Signaling and Regulates the Alcohol Oxidase 1 (AOX1) Promoter in Pichia pastoris.

    Science.gov (United States)

    Wang, Xiaolong; Wang, Qi; Wang, Jinjia; Bai, Peng; Shi, Lei; Shen, Wei; Zhou, Mian; Zhou, Xiangshan; Zhang, Yuanxing; Cai, Menghao

    2016-03-18

    The alcohol oxidase 1 (AOX1) promoter (P AOX1) of Pichia pastoris is the most powerful and commonly used promoter for driving protein expression. However, mechanisms regulating its transcriptional activity are unclear. Here, we identified a Zn(II)2Cys6-type methanol-induced transcription factor 1 (Mit1) and elucidated its roles in regulating PAOX1 activity in response to glycerol and methanol. Mit1 regulated the expression of many genes involved in methanol utilization pathway, including AOX1, but did not participate in peroxisome proliferation and transportation of peroxisomal proteins during methanol metabolism. Structural analysis of Mit1 by performing domain deletions confirmed its specific and critical role in the strict repression of P AOX1 in glycerol medium. Importantly, Mit1, Mxr1, and Prm1, which positively regulated P AOX1 in response to methanol, were bound to P AOX1 at different sites and did not interact with each other. However, these factors cooperatively activated P AOX1 through a cascade. Mxr1 mainly functioned during carbon derepression, whereas Mit1 and Prm1 functioned during methanol induction, with Prm1 transmitting methanol signal to Mit1 by binding to the MIT1 promoter (P MIT1), thus increasingly expressing Mit1 and subsequently activating P AOX1. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  17. The knockdown of OsVIT2 and MIT affects iron localization in rice seed.

    Science.gov (United States)

    Bashir, Khurram; Takahashi, Ryuichi; Akhtar, Shamim; Ishimaru, Yasuhiro; Nakanishi, Hiromi; Nishizawa, Naoko K

    2013-11-20

    The mechanism of iron (Fe) uptake in plants has been extensively characterized, but little is known about how Fe transport to different subcellular compartments affects Fe localization in rice seed. Here, we discuss the characterization of a rice vacuolar Fe transporter 2 (OsVIT2) T-DNA insertion line (osvit2) and report that the knockdown of OsVIT2 and mitochondrial Fe transporter (MIT) expression affects seed Fe localization. osvit2 plants accumulated less Fe in their shoots when grown under normal or excess Fe conditions, while the accumulation of Fe was comparable to that in wild-type (WT) plants under Fe-deficient conditions. The accumulation of zinc, copper, and manganese also changed significantly in the shoots of osvit2 plants. The growth of osvit2 plants was also slow compared to that of WT plants. The concentration of Fe increased in osvit2 polished seeds. Previously, we reported that the expression of OsVIT2 was higher in MIT knockdown (mit-2) plants, and in this study, the accumulation of Fe in mit-2 seeds decreased significantly. These results suggest that vacuolar Fe trafficking is important for plant Fe homeostasis and distribution, especially in plants grown in the presence of excess Fe. Moreover, changes in the expression of OsVIT2 and MIT affect the concentration and localization of metals in brown rice as well as in polished rice seeds.

  18. Shakespeare for all Seasons ? Richard II en Avignon : de Jean Vilar (1957 à Ariane Mnouchkine (1982 Shakespeare for All Seasons? Richard II at the Avignon Festival: from Jean Vilar (1957 to Ariane Mnouchkine (1982

    Directory of Open Access Journals (Sweden)

    Isabelle Schwartz-Gastine

    2009-06-01

    Full Text Available Richard II has not often been performed on the French stage; however, in the 20th century, within a period of 35 years, two productions premiered at the same venue (the Cour d’Honneur at the open-air Avignon Festival, were so successful that they became emblematic of their times. In 1947 Jean Vilar opened the first Avignon Festival with an ascetic, charismatic eponymous hero who came to an inner knowledge of himself in his bare prison cell; in 1982 Ariane Mnouchkine offered a splendid visual display by transposing the play into the kabuki tradition; this offered the audience breath-taking and dynamic tableaux of elaborate court ceremonies and rebellious lords.At such a distance in time, the English medieval code of honour was dealt with according to completely different theatrical principles of ethics and aesthetics, mirroring the changes in perspective within French society.

  19. MITR-III: Upgrade and relicensing studies for the MIT Research Reactor. Second annual report

    International Nuclear Information System (INIS)

    Trosman, H.G.; Lanning, D.D.; Harling, O.K.

    1994-08-01

    The current operating license of the MIT research reactor will expire on May 7, 1996 or possibly a few years later if the US Nuclear Regulatory Commission agrees that the license period can start with the date of initial reactor operation. Driven by the imminent expiration of the operating license, a team of nuclear engineering staff and students have begun a study of the future options for the MIT Research Reactor. These options have included the range from a major rebuilding of the reactor to its decommissioning. This document reports the results of a two year intensive activity which has been supported by a $148,000 grant from the USDOE contract Number DEFG0293ER75859, approximately $100,000 of internal MIT funds and Nuclear Engineering Department graduate student fellowships as well as assistance from international visiting scientists and engineers

  20. MIT Clean Energy Prize: Final Technical Report May 12, 2010 - May 11, 2011

    Energy Technology Data Exchange (ETDEWEB)

    Snyder, Chris [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Campbell, Georgina [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Salony, Jason [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Aulet, Bill [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

    2011-08-09

    The MIT Clean Energy Prize (MIT CEP) is a venture creation and innovation competition to encourage innovation in the energy space, specifically with regard to clean energy. The Competition invited student teams from any US university to submit student-led ventures that demonstrate a high potential of successfully making clean energy more affordable, with a positive impact on the environment. By focusing on student ventures, the MIT CEP aims to educate the next generation of clean energy entrepreneurs. Teams receive valuable mentoring and hard deadlines that complement the cash prize to accelerate development of ventures. The competition is a year-long educational process that culminates in the selection of five category finalists and a Grand Prize winner and the distribution of cash prizes to each of those teams. Each entry was submitted in one of five clean energy categories: Renewables, Clean Non-Renewables, Energy Efficiency, Transportation, and Deployment.

  1. An Approach for Prevention of MitM Attack Based on Rogue AP in Wireless Network

    Directory of Open Access Journals (Sweden)

    Zhendong Wu

    2014-12-01

    Full Text Available With the rapid development of WLAN, more and more schools and businesses have begun to provide the WLAN for users. However, WLAN is considerably more susceptible to MitM (man- in-the-middle attack. To overcome it, we propose a dynamic password technology named Two-way Dynamic Authentication Technology (TDAT. It uses two-factor during the initial authentication, and uses a two-way hash chain during the cross-domain authentication. TDAT effectively protects users' authentication credentials and improves users' experience. In an actual wireless network environment, we implement a MitM attack framework based on Rogue AP. Then we effectively prevent this MitM attack by using TDAT. Moreover we analyze the security of TDAT by using BAN logic.

  2. Long-lived mitochondrial (Mit) mutants of Caenorhabditis elegans utilize a novel metabolism.

    Science.gov (United States)

    Butler, Jeffrey A; Ventura, Natascia; Johnson, Thomas E; Rea, Shane L

    2010-12-01

    The Caenorhabditis elegans mitochondrial (Mit) mutants have disrupted mitochondrial electron transport chain (ETC) functionality, yet, surprisingly, they are long lived. We have previously proposed that Mit mutants supplement their energy needs by exploiting alternate energy production pathways normally used by wild-type animals only when exposed to hypoxic conditions. We have also proposed that longevity in the Mit mutants arises as a property of their new metabolic state. If longevity does arise as a function of metabolic state, we would expect to find a common metabolic signature among these animals. To test these predictions, we established a novel approach monitoring the C. elegans exometabolism as a surrogate marker for internal metabolic events. Using HPLC-ultraviolet-based metabolomics and multivariate analyses, we show that long-lived clk-1(qm30) and isp-1(qm150) Mit mutants have a common metabolic profile that is distinct from that of aerobically cultured wild-type animals and, unexpectedly, wild-type animals cultured under severe oxygen deprivation. Moreover, we show that 2 short-lived mitochondrial ETC mutants, mev-1(kn1) and ucr-2.3(pk732), also share a common metabolic signature that is unique. We show that removal of soluble fumarate reductase unexpectedly increases health span in several genetically defined Mit mutants, identifying at least 1 alternate energy production pathway, malate dismutation, that is operative in these animals. Our study suggests long-lived, genetically specified Mit mutants employ a novel metabolism and that life span may well arise as a function of metabolic state.

  3. The R Package MitISEM: Efficient and Robust Simulation Procedures for Bayesian Inference

    Directory of Open Access Journals (Sweden)

    Nalan Baştürk

    2017-07-01

    Full Text Available This paper presents the R package MitISEM (mixture of t by importance sampling weighted expectation maximization which provides an automatic and flexible two-stage method to approximate a non-elliptical target density kernel - typically a posterior density kernel - using an adaptive mixture of Student t densities as approximating density. In the first stage a mixture of Student t densities is fitted to the target using an expectation maximization algorithm where each step of the optimization procedure is weighted using importance sampling. In the second stage this mixture density is a candidate density for efficient and robust application of importance sampling or the Metropolis-Hastings (MH method to estimate properties of the target distribution. The package enables Bayesian inference and prediction on model parameters and probabilities, in particular, for models where densities have multi-modal or other non-elliptical shapes like curved ridges. These shapes occur in research topics in several scientific fields. For instance, analysis of DNA data in bio-informatics, obtaining loans in the banking sector by heterogeneous groups in financial economics and analysis of education's effect on earned income in labor economics. The package MitISEM provides also an extended algorithm, 'sequential MitISEM', which substantially decreases computation time when the target density has to be approximated for increasing data samples. This occurs when the posterior or predictive density is updated with new observations and/or when one computes model probabilities using predictive likelihoods. We illustrate the MitISEM algorithm using three canonical statistical and econometric models that are characterized by several types of non-elliptical posterior shapes and that describe well-known data patterns in econometrics and finance. We show that MH using the candidate density obtained by MitISEM outperforms, in terms of numerical efficiency, MH using a simpler

  4. Initiation of a phase-I trial of neutron capture therapy at the MIT research reactor

    International Nuclear Information System (INIS)

    Harling, O.K.; Bernard, J.A.; Yam, Chun-Shan

    1995-01-01

    The Massachusetts Institute of Technology (MIT), the New England Medical Center (NEMC), and Boston University Medical Center (BUMC) initiated a phase-1 trial of boron neutron capture therapy (BNCT) on September 6, 1994, at the 5-MW(thermal) MIT research reactor (MITR). A novel form of experimental cancer therapy, BNCT is being developed for certain types of highly malignant brain tumors such as glioblastoma and melanoma. The results of the phase-1 trials on patients with tumors in the legs or feet are described

  5. Rehkitzrettung mit dem Fliegenden Wildretter: Erfahrungen der ersten Feldeinsätze

    OpenAIRE

    Wimmer, Tilman; Israel, Martin; Haschberger, Peter; Weimann, Anita

    2013-01-01

    Der Fliegende Wildretter des Deutschen Zentrums für Luft- und Raumfahrt ist als prototypische Kleinserie seit dem Jahr 2010 erfolgreich in Deutsch-land und Österreich im Einsatz, um aus der Luft Wildtiere während der Wiesenmahd aufzuspüren, und diese so vor dem Tod durch das Mähwerk zu retten. Der Prototyp basiert auf einem ferngesteuerten Multikopter, der mit mehreren Kameras ausgestattet ist und damit im Flug zuverlässiger und wesentlich schneller Wildtiere er-kennen kann, als dies mit b...

  6. Verbesserte Visualisierung der Koronararterien in MSCT-Daten mit direkter Vergleichbarkeit zur Angiographie

    Science.gov (United States)

    Lacalli, Christina; Jähne, Marion; Wesarg, Stefan

    In diesem Beitrag stellen wir neue, automatisierte Verfahren zur Visualisierung der Koronararterien einerseits und für eine direkte Vergleichbarkeit mit konventionellen Angiogrammen andererseits vor. Unser Ansatz umfasst Methoden für die automatische Extraktion des Herzens aus kontrastverstärkten CT-Daten, sowie für die Maskierung grosser kontrastmittelgefüllter Kavitäten des Herzens, um die Sichtbarkeit der Koronararterien bei der Darstellung mittels Volumenrendering zu verbessern. Zum direkten Vergleich mit konventionellen Angiographien wurde ein Verfahren zur automatischen Generierung von Projektionsansichten aus den CT-Daten entwickelt.

  7. Therapie einer postoperativ entstandenen zystischen Raumforderung mit Picibanil (OK-432): Ein Fallbericht

    OpenAIRE

    Schlüter, A; Weller, P; Mattheis, S; Lang, S

    2014-01-01

    Einleitung: Picibanil (=OK432) ist ein Lysat bestehend aus Penicillin G und mit H2O2 attenuiertem Streptococcus pyogenes. In den letzten Jahrzehnten wurde Picibanil zur Therapie von Pleuraergüssen, Lymphangiomen, Chylusfisteln, medianen Halszysten und Ranulae eingesetzt. Es verursacht eine Immunreaktion mit aseptischer Entzündung. Dies führt zu einer Zerstörung des Endothels und konsekutiv zu einer Verklebung und Schrumpfung des Zystensacks.Falldarstellung: Wir berichten über einen 40-jähri...

  8. Entre el Dios de Paley y el Dios de Bonnet: El Parco Evolucionismo Teísta de Richard Owen

    Directory of Open Access Journals (Sweden)

    Gustavo Caponi

    2013-04-01

    Full Text Available Firstly, in this article it is examined the nature of the putative remarks concerning evolution of species that are found in the works that Richard Owen published before 1858; and then it is made the same thing with the few and vague evolutionist conjectures that Owen certainly made after the public presentation of Natural Selection Theory. Regarding the former topic, the goal will be to highlight the ambiguity of those Owen’s remarks, and concerning the latter topic what is looked for is to show that, when he explained his transmutationist thesis, Owen didn’t go beyond a pious theistic evolutionism, without postulating any mechanism of evolutionary change and remaining faithful to Design Theology praised by Paley.

  9. Entre el Dios de Paley y el Dios de Bonnet: El Parco Evolucionismo Teísta de Richard Owen

    OpenAIRE

    Gustavo Caponi

    2013-01-01

    http://dx.doi.org/10.5007/1808-1711.2013v17n1p71En primer lugar, en este artículo se examina el carácter de las putativas referencias a la evolución de las especies que encontramos en las obras que Richard Owen publicó antes de 1858; y luego se analizan las escazas y vagas conjeturas evolucionistas que Owen sin duda formuló con posterioridad a la presentación pública de la Teoría de la Selección Natural.  En lo que respecta a lo primero, el objetivo es subrayar la ambigüedad de esas referenci...

  10. Exact solutions to traffic density estimation problems involving the Lighthill-Whitham-Richards traffic flow model using mixed integer programming

    KAUST Repository

    Canepa, Edward S.; Claudel, Christian G.

    2012-01-01

    This article presents a new mixed integer programming formulation of the traffic density estimation problem in highways modeled by the Lighthill Whitham Richards equation. We first present an equivalent formulation of the problem using an Hamilton-Jacobi equation. Then, using a semi-analytic formula, we show that the model constraints resulting from the Hamilton-Jacobi equation result in linear constraints, albeit with unknown integers. We then pose the problem of estimating the density at the initial time given incomplete and inaccurate traffic data as a Mixed Integer Program. We then present a numerical implementation of the method using experimental flow and probe data obtained during Mobile Century experiment. © 2012 IEEE.

  11. Exact solutions to traffic density estimation problems involving the Lighthill-Whitham-Richards traffic flow model using mixed integer programming

    KAUST Repository

    Canepa, Edward S.

    2012-09-01

    This article presents a new mixed integer programming formulation of the traffic density estimation problem in highways modeled by the Lighthill Whitham Richards equation. We first present an equivalent formulation of the problem using an Hamilton-Jacobi equation. Then, using a semi-analytic formula, we show that the model constraints resulting from the Hamilton-Jacobi equation result in linear constraints, albeit with unknown integers. We then pose the problem of estimating the density at the initial time given incomplete and inaccurate traffic data as a Mixed Integer Program. We then present a numerical implementation of the method using experimental flow and probe data obtained during Mobile Century experiment. © 2012 IEEE.

  12. HOW CAN LOVE BE VIOLENT? REFLECTIONS ON RICHARD OF ST.VICTOR’S ON THE FOUR DEGREES OF VIOLENT LOVE

    Directory of Open Access Journals (Sweden)

    MARIUS TALOŞ

    2012-05-01

    Full Text Available The following article focuses on Richard of St. Victor´s most original treatise: On the Four Degrees of Violent Love. Although the topic of violence within the Christian view on ethics, politics and theology was not at all new by 1173, the major contribution of this short but dense mystical writing consists in developing systematically the violence as an inherent consequence of the infinite charity. The love is so powerful that it “wounds, binds, languishes and brings on a faint”, but the same force may have different effects: if these four steps appear to be destructive when oriented to satisfy the “profane” desires, their infinite strength show providential effects when turned to the divine source of the charity.

  13. Mit1 Transcription Factor Mediates Methanol Signaling and Regulates the Alcohol Oxidase 1 (AOX1) Promoter in Pichia pastoris*

    Science.gov (United States)

    Wang, Xiaolong; Wang, Qi; Wang, Jinjia; Bai, Peng; Shi, Lei; Shen, Wei; Zhou, Mian; Zhou, Xiangshan; Zhang, Yuanxing; Cai, Menghao

    2016-01-01

    The alcohol oxidase 1 (AOX1) promoter (PAOX1) of Pichia pastoris is the most powerful and commonly used promoter for driving protein expression. However, mechanisms regulating its transcriptional activity are unclear. Here, we identified a Zn(II)2Cys6-type methanol-induced transcription factor 1 (Mit1) and elucidated its roles in regulating PAOX1 activity in response to glycerol and methanol. Mit1 regulated the expression of many genes involved in methanol utilization pathway, including AOX1, but did not participate in peroxisome proliferation and transportation of peroxisomal proteins during methanol metabolism. Structural analysis of Mit1 by performing domain deletions confirmed its specific and critical role in the strict repression of PAOX1 in glycerol medium. Importantly, Mit1, Mxr1, and Prm1, which positively regulated PAOX1 in response to methanol, were bound to PAOX1 at different sites and did not interact with each other. However, these factors cooperatively activated PAOX1 through a cascade. Mxr1 mainly functioned during carbon derepression, whereas Mit1 and Prm1 functioned during methanol induction, with Prm1 transmitting methanol signal to Mit1 by binding to the MIT1 promoter (PMIT1), thus increasingly expressing Mit1 and subsequently activating PAOX1. PMID:26828066

  14. Memoria y Estudios Culturales : un acercamiento al relato sobre la propia historia de vida en Raymond Williams y Richard Hoggart

    Directory of Open Access Journals (Sweden)

    Sebastián Matías Stra

    2018-01-01

    Full Text Available [es] Este trabajo intentará recuperar, de forma parcial y fragmentaria, las maneras en que el testimonio en primera persona articulado en el formato de memorias de la propia historia de vida tiene un posible valor metodológico en algunos textos seminales de la conformación de los estudios culturales ingleses. Hablamos particularmente del libro de 1957, The Uses of Literacy: Aspects of Working-class Life, with Special Reference to Publications and Entertainments, de Richard Hoggart y del tradicional artículo Culture is Ordinary de Raymond Williams, publicado en 1958 y que incluye de forma más rudimentaria algunas definiciones que conformaron la primera parte de la obra del autor galés, constituida por los libros Culture and Society y The Long Revolution. [en] This work will attempt to partially and fragmentarily recover the ways in which the testimony in first person articulated in the format of memories of the own history of life has a possible methodological value in some seminal texts of the conformation of the english cultural studies. We refer in special to the 1957 book, The Uses of Literacy: Aspects of Working-class Life, with Special Reference to Publications and Entertainments, by Richard Hoggart and the Raymond Williams' article Culture is Ordinary, published in 1958, which includes, in an incipient way, some of the definitions that formed the first part of the work of the Welsh author, made up of the books Culture and Society and The Long Revolution.

  15. The relationship between ethics and human rights in the thought of Richard Rorty

    Directory of Open Access Journals (Sweden)

    Mohammad Taghi Qezelsofla

    2014-04-01

    Full Text Available In general, two theories or school of thoughts had been prevailed in modern moral philosophies until recently. Ethical school of thought of "task-oriented", in which the emphasis is on the nature of the action. At first, this school of thought was considered by Immanuel Kant. Accordingly, doing or will to do every action should be such that become a universal moral law. In contrast, another ethical school of thought known as "utilitarianism ethics" was introduced by Jeremy Bentham and John Stuart Mill. Here, we give priority to those moral actions that can bring the greatest happiness for most people. In three or four recent decades, coinciding with the linguistic and cognitive turn, which has become known as the transition from positivism to post-positivism, another challenge has been raised in discussing philosophy of ethics by Richard Rorty which is related to his claim regarding the requirements of the current multiple world. This claim can make a new relation between morality and human rights. Hence, the main hypothesis of this paper is to clarify the point that Rorty has raised his claim by combining the theory of pragmatism and postmodern Ethics. To prove this hypothesis, this article has been set in two sections, in the first section in order to become familiar with Rorty's creed-breaker thought, the foundations of the philosophy of ethics is discussed. In the second section and under the discussion of ethics based on the rights of human, some of its characteristics will be analyzed. This article has been prepared by a descriptive method through the content analysis of various works of Rorty. Theoretical support for this article is a critical-normative approach. به طور کلی در فلسفه‌های اخلاق مدرن تا این اواخر دو نگره یا مکتب حاکم بوده است. مکتب اخلاق «وظیفه‌گرا»که در آن بر ماهیت کنش تأکید می‌شود. این مکتب ابتدا

  16. HealthSouth's most wanted. Founder and former chairman and CEO Richard Scrushy is indicted for 85 counts of conspiracy, fraud and money laundering.

    Science.gov (United States)

    Piotrowski, Julie

    2003-11-10

    Wake-up call for the industry or an isolated case of corporate chicanery? Healthcare experts are divided on the import of Richard Scrushy's indictment on 85 counts last week in connection with the financial scandal at HealthSouth Corp. The indictment alleges the company founder relied on electronic and telephone surveillance, threats and intimidation to control his accomplices.

  17. Hamilton on surnud, tema mõju mitte : in memoriam Richard Hamilton (24. II 1922 - 13. IX 2011) / Kadri Karro ; kommenteerinud Eha Komissarov, Sirje Helme, Jaak Kangilaski

    Index Scriptorium Estoniae

    Karro,Kadri

    2011-01-01

    Briti kunstniku Richard Hamiltoni (1922 - 2011) loomingust eesti kunstiteadlaste Eha Komissarovi, Sirje Helme ja Jaak Kangilaski pilgu läbi. Lähemalt 1956. aastal valminud kollaažist "Mis teeb tänapäeva kodud nii eriliseks, nii meeldivaks?"

  18. eLearning in der Volksschule – ein Mehrwert? - Aspekte zu einem zukunftsorientierten Unterricht mit IKT

    Directory of Open Access Journals (Sweden)

    Ursula Dopplinger

    2011-09-01

    Full Text Available In einer Panelstudie wurde die Verbesserung der Schlüsselkompetenzen von Schülerinnen und Schülern durch eLearning in vier Volksschulen untersucht. Mit der verwendeten Webquest-Methode wurden bei drei von vier Untersuchten im Bereich der Schlüsselkompetenzen Erfolge erzielt.

  19. Energiemessungen bei Aspergillus niger mit Hilfe eines automatischen Mikro-Kompensations-Calorimeters

    NARCIS (Netherlands)

    Algera, Leendert

    1932-01-01

    Beschrieben wurde ein Calorimeter. Das Prinzip der Warmemessung besteht darin, dasz die entwickelte Wärme, sobald sie entsteht, durch eine entsprechende Kältemenge kompensiert wird. Sobald die Temperatur des Kulturgefaszes ein wenig ansteigt, wird trockne Luft gepumpt durch ein mit Wasser gefulltes

  20. Renaissance des Mittelalters (Teil 1) : oder Alte Fragen mit Neuen Antworten

    NARCIS (Netherlands)

    drs. Frans van den Reep

    2014-01-01

    Man kann das Heute mit keiner Zeit vorher vergleichen? Zu schnell sind die Veränderungen, zu gravierend die technologischen Möglichkeiten der Digitalisierung, des Internets? Frans van der Reep nähert sich in vielen überraschenden Parallelen in der gesellschaftlichen Entwicklung dem Gestern und

  1. Crash tests with Smartcrash barriers, a technology with a future; Zukunftssichere Crashtests mit Smartcrash-Barrieren

    Energy Technology Data Exchange (ETDEWEB)

    Barz, D.; Evers, W. [Kistler Instrumente AG (Switzerland). Geschaeftsbereich Fahrzeugmesstechnik

    2005-02-01

    The Smartcrash barrier by Kistler is a completely new technology. State-of-the-art data processing with Microdau modules is combined with a singular mechanical modularity which meets all requirements of present and future crash standards. Together with a piezo measuring system perfectly tuned to the highly dynamic processes during crash tests, this provides a basis for making crash laboratories economically efficient, with safe and accurate data, and compatible with other measuring systems. The system is a 'must' for every modern crash laboratory. (orig.) [German] Die Smartcrash-Barriere von Kistler setzt in jeder Hinsicht Massstaebe. Neueste Technologie der Datenverarbeitung beim Crash mit Microdau-Modulen, wie sie auch in Dummys eingesetzt werden, wird mit einer einzigartigen mechanischen Modularitaet kombiniert, die alle erforderlichen Voraussetzungen fuer bestehende und zukuenftige Crash-Standards bietet. In Verbindung mit der fuer die Messung von hochdynamischen Kraftverlaeufen beim Crash praedestinierte Piezo-Messtechnik ist hiermit die Basis geschaffen, Crash-Laboratorien wirtschaftlich und hinsichtlich des Datenakquisition sicher und kompatibel mit anderen Messgroessen im Labor auszuruesten. Ein 'Muss' fuer jedes moderne Crash-Labor. (orig.)

  2. Pack also the sauna. Integration of electricity storage; Auch die Sauna mit rein. Einbindung von Stromspeichern

    Energy Technology Data Exchange (ETDEWEB)

    Ullrich, Sven

    2013-10-01

    The installers have to handle with a variety of variables and options to plan and integrate the correct personal use system of solar power systems for their customers. [German] Die Installateure muessen mit einer Vielzahl von Variablen und Varianten zurechtkommen, um das richtige Eigenverbrauchssystem einer Solarstromanlage fuer ihre Kunden zu planen und einzubauen.

  3. Underground storage with floating cover. An overview; Erdbeckenspeicher mit schwimmender Abdeckung. Eine Uebersicht

    Energy Technology Data Exchange (ETDEWEB)

    Heller, A.; Maureschat, G.; Duer, K. [Technical Univ. of Denmark, Lyngby (Denmark). Dept. of Buildings and Energy

    1998-12-31

    A number of underground stores have been developed in recent years in Denmark. The development has been subsidised with funds of `Development program renewable energy` launched by the Danish Ministry for Environment and Energy. First experience reports on underground storage show that more emphasis must be put on the development of storage sealing and cover construction. Hence research works currently focuses on the investigation of liner material and further development of floating cover constructions. The target is the development of underground storage using solar energy for heating that can compete with conventional heating systems technically and economically. (orig.) [Deutsch] In Daenemark hat man in den letzten Jahren eine Reihe von Erdbeckenspeichern entwickelt. Die Entwicklung wird mit Mitteln aus dem `Entwicklungsprogramm Erneuerbare Energie` vom daenischen Umwelt- und Energieministerium finanziell gefoerdert. Die ersten Erfahrungen mit Erdbeckenspeichern haben gezeigt, dass ein verstaerkter Einsatz bei der Entwicklung von Abdichtungen des Speichers und von Deckelkonstruktionen gefordert ist. Deshalb wird in Daenemark aktuell mit der Untersuchung von Linermaterialien und der Weiterentwicklung von schwimmenden Deckelkonstruktionen gearbeitet. Das Ziel dieser Arbeit ist es, Erdbeckenspeicher zu entwickeln, die die Ausnutzung von Sonnenenergie zur Waermeversorgung im Vergleich mit herkoemmlicher Waermeversorgung sowohl technisch als auch oekonomisch konkurrenzfaehig macht. (orig.)

  4. The R package MitISEM : efficient and robust simulation procedures for Bayesian inference

    NARCIS (Netherlands)

    Baştürk, N.; Grassi, S.; Hoogerheide, L.; Opschoor, A.; van Dijk, H.K.

    2015-01-01

    This paper presents the R package MitISEM (mixture of t by importance sampling weighted expectation maximization) which provides an automatic and flexible two-stage method to approximate a non-elliptical target density kernel - typically a posterior density kernel - using an adaptive mixture of

  5. MitBASE : a comprehensive and integrated mitochondrial DNA database. The present status

    NARCIS (Netherlands)

    Attimonelli, M.; Altamura, N.; Benne, R.; Brennicke, A.; Cooper, J. M.; D'Elia, D.; Montalvo, A.; Pinto, B.; de Robertis, M.; Golik, P.; Knoop, V.; Lanave, C.; Lazowska, J.; Licciulli, F.; Malladi, B. S.; Memeo, F.; Monnerot, M.; Pasimeni, R.; Pilbout, S.; Schapira, A. H.; Sloof, P.; Saccone, C.

    2000-01-01

    MitBASE is an integrated and comprehensive database of mitochondrial DNA data which collects, under a single interface, databases for Plant, Vertebrate, Invertebrate, Human, Protist and Fungal mtDNA and a Pilot database on nuclear genes involved in mitochondrial biogenesis in Saccharomyces

  6. Biogas - a new energy source saves fossil resources; Biogas - mit neuer Energie Ressourcen schonen

    Energy Technology Data Exchange (ETDEWEB)

    Thoss, C. (comp.)

    2001-07-01

    The new German Renewable Energy Sources Act (EEG) of 2000 made conditions for biogas more favourable - small wonder, as the German Biogas Association (Fachverband Biogas e.V.) co-operated with written expert opinions and many discussions with decision-makers. The subjects discussed at the 10th Biogas Conference reflect the current situation and will provide a basis for committee work in 2001. [German] Im Jahr 2000 haben sich die gesetzlichen Rahmenbedingungen fuer den Biogasbereich mit dem Inkrafttreten des erneuerbaren Energiegesetz (EEG) sehr positiv entwickelt. Der Fachverband Biogas e.V. hat mit schriftlichen Stellungnahmen und in vielen Gespraechen mit Entscheidungstraegern diese Bedingungen mitgestaltet. In Zukunft gibt es noch viele Aufgaben fuer eine effektive Interessenvertretung der Biogasbranche auf Laender- und Bundesebene. Die Themen, die auf der 10. Biogastagung diskutiert werden, spiegeln die Fragen wieder, die unter Experten derzeit intensiv diskutiert werden. Die Ergebnisse des Erfahrungsaustausches auf dieser Tagung werden die Grundlage fuer die Arbeit der Gremien im Fachverband Biogas im Jahr 2001 sein. Mit dem vorliegenden Tagungsband ist es gelungen, die Basis fuer die fachlichen Gespraeche waehrend und nach der Tagung schaffen. (orig.)

  7. Review of 'Where the action is, by Paul Dorish, MIT Press 2001

    DEFF Research Database (Denmark)

    Wentzer, Helle

    2008-01-01

    Bogen til human-computer interaction, HCI er ikke helt ny (MIT 2001/2004), men dog filosofisk aktuel som baggrund for nye tanker, forventninger og krav til sundhedsinformatikken. Den foranker forskningprogrammerne til ’tangible computing’ og ’social computing’ paradigmatisk i fænomenologien og...

  8. Evaluation of the MIT-Scan-T2 for non-destructive PCC pavement thickness determination.

    Science.gov (United States)

    2008-07-01

    The MIT-Scan-T2 device is marketed as a non-destructive way to determine pavement thickness on both : HMA and PCC pavements. PCC pavement thickness determination is an important incentivedisincentive : measurement for the Iowa DOT and contractors. Th...

  9. Schwerpunktseminar : "Dazugehören? Umgang mit Minderheiten" / Liliāna Vancāne

    Index Scriptorium Estoniae

    Vancāne, Liliāna

    2016-01-01

    17. -20. märtsini 2016 Tartus toimunud seminarist "Dazugehören? Umgang mit Minderheiten. Estland und Lettland gestern-heutu-morgen". Seminarist sotsiaalse kuuluvuse ja vähemuste teemal. Suurepäraselt korraldatud ürituse parim osa oli töötuba

  10. You Don't Need Richards'... A New General 1-D Vadose Zone Solution Method that is Reliable

    Science.gov (United States)

    Ogden, F. L.; Lai, W.; Zhu, J.; Steinke, R. C.; Talbot, C. A.

    2015-12-01

    Hydrologic modelers and mathematicians have strived to improve 1-D Richards' equation (RE) solution reliability for predicting vadose zone fluxes. Despite advances in computing power and the numerical solution of partial differential equations since Richards first published the RE in 1931, the solution remains unreliable. That is to say that there is no guarantee that for a particular set of soil constitutive relations, moisture profile conditions, or forcing input that a numerical RE solver will converge to an answer. This risk of non-convergence renders prohibitive the use of RE solvers in hydrological models that need perhaps millions of infiltration solutions. In lieu of using unreliable numerical RE solutions, researchers have developed a wide array of approximate solutions that more-or-less mimic the behavior of the RE, with some notable deficiencies such as parameter insensitivity or divergence over time. The improved Talbot-Ogden (T-O) finite water-content scheme was shown by Ogden et al. (2015) to be an extremely good approximation of the 1-D RE solution, with a difference in cumulative infiltration of only 0.2 percent over an 8 month simulation comparing the improved T-O scheme with a RE numerical solver. The reason is that the newly-derived fundamental flow equation that underpins the improved T-O method is equivalent to the RE minus a term that is equal to the diffusive flux divided by the slope of the wetting front. Because the diffusive flux has zero mean, this term is not important in calculating the mean flux. The wetting front slope is near infinite (sharp) in coarser soils that produce more significant hydrological interactions between surface and ground waters, which also makes this missing term 1) disappear in the limit, and, 2) create stability challenges for the numerical solution of RE. The improved T-O method is a replacement for the 1-D RE in soils that can be simulated as homogeneous layers, where the user is willing to neglect the effects

  11. Nanomedical strategy to prolong survival period, heighten cure rate, and lower systemic toxicity of S180 mice treated with MTX/MIT.

    Science.gov (United States)

    Song, Ning; Zhao, Ming; Wang, Yuji; Hu, Xi; Wu, Jianhui; Jiang, Xueyun; Li, Shan; Cui, Chunying; Peng, Shiqi

    2016-01-01

    In spite of the usual combination form of methotrexate (MTX)/mitoxantrone (MIT) and various complex combination regimens of MTX/MIT with other anticancer drugs, the survival period, cure rate, and systemic toxicity still need to be improved. For this purpose, a nanostructured amino group-modified mesoporous silica nanoparticles (MSNN)-MTX/MIT was designed. In the preparation, the surface of mesoporous silica nanoparticles (MSNs) was modified with amino groups to form MSNN. The covalent modification of the amino groups on the surface of MSNN with MTX resulted in MSNN-MTX. The loading of MIT into the surface pores of MSNN-MTX produced nanostructured MSNN-MTX/MIT. Compared with the usual combination form (MTX/MIT), nanostructured MSNN-MTX/MIT increased the survival period greatly, heightened the cure rate to a great extent, and lowered the systemic toxicity of the treated S180 mice, significantly. These superior in vivo properties of nanostructured MSNN-MTX/MIT over the usual combination form (MTX/MIT) were correlated with the former selectively releasing MTX and MIT in tumor tissue and inside cancer cells in vitro. The chemical structure and the nanostructure of MSNN-MTX/MIT were characterized using infrared and differential scanning calorimeter spectra as well as transmission electron microscope images, respectively.

  12. Entre el dios de Paley y el dios de Bonnet - El parco evolucionismo teísta de Richard Owen

    Directory of Open Access Journals (Sweden)

    Gustavo Caponi

    2013-04-01

    Full Text Available http://dx.doi.org/10.5007/1808-1711.2013v17n1p71 En primer lugar, en este artículo se examina el carácter de las putativas referencias a la evolución de las especies que encontramos en las obras que Richard Owen publicó antes de 1858; y luego se analizan las escazas y vagas conjeturas evolucionistas que Owen sin duda formuló con posterioridad a la presentación pública de la Teoría de la Selección Natural.  En lo que respecta a lo primero, el objetivo es subrayar la ambigüedad de esas referencias de Owen; y en lo que respecta a lo segundo lo que interesa es mostrar que, a la hora de explicitar sus tesis evolucionistas, Owen no fue más allá de un pío evolucionismo teísta que, sin postular ningún mecanismo del cambio evolutivo, permanecía fiel a la Teología del diseño preconizada por Paley.

  13. The Road Movies' Space Dynamics in the 70s: Richard C. Sarafian, Monte Hellman and Terrence Malick

    Directory of Open Access Journals (Sweden)

    Filipa Rosário

    2014-07-01

    Full Text Available Vanishing Point (Richard C. Sarafian, 1971, Two-lane Blacktop (Monte Hellmann, 1971 and Badlands (Terrence Malick, 1973 are road movies that incorporate distinctive journeys, which, at a certain moment, become similar. Their heroes act as non-mystical pilgrims to whom the trip is a journey in itself, even if they come up as a chase, a car race or an escape from the police.In a filmic genre built from the spatial element, the road life structures each narrative in each film. In this way, the moment when the journey looses its teleological sense acquires even more relevance, allowing us to understand the genre’s space dynamics with a different depth.In this essay, I will analyse comparatively the ways through which characters and directors relate to the scenery/landscape, in order to identify ideological constraints related to space, i.e., those symbolic limitations the road movie seems to conceal. Easy Rider (Dennis Hopper, 1969 will be a constant presence since, as the inaugural road movie, it has determined the genre’s underlying forces.

  14. An analytical solution of Richards' equation providing the physical basis of SCS curve number method and its proportionality relationship

    Science.gov (United States)

    Hooshyar, Milad; Wang, Dingbao

    2016-08-01

    The empirical proportionality relationship, which indicates that the ratio of cumulative surface runoff and infiltration to their corresponding potentials are equal, is the basis of the extensively used Soil Conservation Service Curve Number (SCS-CN) method. The objective of this paper is to provide the physical basis of the SCS-CN method and its proportionality hypothesis from the infiltration excess runoff generation perspective. To achieve this purpose, an analytical solution of Richards' equation is derived for ponded infiltration in shallow water table environment under the following boundary conditions: (1) the soil is saturated at the land surface; and (2) there is a no-flux boundary which moves downward. The solution is established based on the assumptions of negligible gravitational effect, constant soil water diffusivity, and hydrostatic soil moisture profile between the no-flux boundary and water table. Based on the derived analytical solution, the proportionality hypothesis is a reasonable approximation for rainfall partitioning at the early stage of ponded infiltration in areas with a shallow water table for coarse textured soils.

  15. Invertendo a “Passagem Atlântica”: O “regresso” de Richard Wright a África

    Directory of Open Access Journals (Sweden)

    Ana Luísa Saraiva

    2012-10-01

    Full Text Available O texto discute o sentido polémico do “regresso” a África que Richard Wright inscreve em Black Power e a forma como a narrativa da viagem subverte a “Middle Passage”. O sujeito narrativo orienta o leitor através de uma incursão pessoal nos muitos sentidos da modernidade e desdobra a noção de “destino comum”, já apontada em 12 Million Black Voices. Contudo, qualquer sentido de comunidade é aqui necessariamente ambíguo, por estar sempre relacionado com questões de raça e identidade. Black Power é uma narrativa importante para o conceito de modernidade e assinala uma mudança significativa na produção literária de Wright para uma vertente não-ficcional. Esta segunda fase da sua obra contém, no entanto, um paradoxo crucial: enquanto se volta para o exterior, para o mundo mais global, Wright tenta, simultaneamente, inscrever-se como referência sobre o locus do qual nunca poderia demarcar‑se: África. Em Black Power, a duboisiana “color line” desdobra‑se em múltiplas dimensões.

  16. ‘The Edification of the Church’: Richard Hooker’s Theology of Worship and the Protestant Inward / Outward Disjunction

    Directory of Open Access Journals (Sweden)

    Littlejohn W. Bradford

    2014-06-01

    Full Text Available Sixteenth-century English Protestants struggled with the legacy left them by the Lutheran reformation: a strict disjunction between inward and outward that hindered the development of a robust theology of worship. For Luther, outward forms of worship had more to do with the edification of the neighbour than they did with pleasing God. But what exactly did ‘edification’ mean? On the one hand, English Protestants sought to avoid the Roman Catholic view that certain elements of worship held an intrinsic spiritual value; on the other hand, many did not want to imply that forms of worship were spiritually arbitrary and had a merely civil value. Richard Hooker developed his theology of worship in response to this challenge, seeking to maintain a clear distinction between the inward worship of the heart and the outward forms of public worship, while refusing to disassociate the two. The result was a concept of edification which sought to do justice to both civil and spiritual concerns, without, pace Peter Lake and other scholars, conceding an inch to a Catholic theology of worship

  17. [Some remarks on the theory of sets by Richard Dedekind and Stanisław Leśniewski].

    Science.gov (United States)

    Obojska, Lidia

    2014-01-01

    Mereology, is a part-whole theory, also called the theory of collective sets. It was founded in 1916 by Stanisław Leśniewski and this is an alternative theory versus the classical set theory by Georg Cantor. These two theories are usually teamed up together as Leśniewski himself was referring to the concept of the set by Cantor and Cantor is considered the "main" ideologist of the set theory. However, when analyzing the original texts of various authors, it seems that the very concept of a collective set is closer to the idea of Richard Dedekind rather than that of Georg Cantor. It is known that Cantor borrowed some concepts on the notion of set from Dedekind, whose ideas were also known to Leśniewski, however, there is no study on this topic. This work is therefore an attempt to compare some set-theoretical concepts of both of these authors, i.e. S. Leśiewski and R. Dedekind and the presentation of their convergence.

  18. Die Dramatikerin Theresia Walser spricht mit Maria Aparecida Barbosa über das Theaterstück "King Kongs Töchter":Mit einer Einführung von Karina Schuller

    OpenAIRE

    Barbosa, M.A. (Maria)

    2012-01-01

    In ihrem Interview spricht die Literaturwissenschaftlerin Maria Aparecida Barbosa mit der Dramatikerin Theresia Walser. Am Beispiel des Theaterstücks King Kongs Töchter (1998), das sich auf groteske Art und Weise mit dem Alltag in einem Altenheim befasst, werden dabei verschiedene Themen angesprochen: Es geht um die Selbstreflexivität des Theaters, um Walsers Verständnis von poetischer Sprache und Realismus sowie um den kreativen Schreibprozess im Allgemeinen. Ergänzt wird das Interview durch...

  19. Verfahren zur Hydroformylierung, Liganden mit von Bisphenol A abgeleiteter Struktur und Katalysator umfassend einen Komplex dieser Liganden

    NARCIS (Netherlands)

    2002-01-01

    Die vorliegende Erfindung betrifft ein Verfahren zur Hydroformylierung ethylenisch ungesättigter Verbindungen, wobei man als Hydroformylierungskatalysator wenigstens einen Komplex eines Metalss der VIII. Nebengruppe mit wenigstens einer phosphorhaltigen Verbindung als Liganden einsetzt, wobei diese

  20. Dewatering of sludge using the hydrosoft high-pressure process; Entwaessern von Schlaemmen mit dem Hydrosoft-Hochdruckverfahren

    Energy Technology Data Exchange (ETDEWEB)

    Eder, C.; Eder, G. [Christian Eder Technology GbR, Neunkirchen (Germany)

    1999-07-01

    The hydrosoft process permits to dewater sludge, especially also sludge from municipal sewage treatment plant, until it contains a high proportion of dry substance. For existing dewatering systems equipped with the long-lived chamber filter presses, too, the dry matter content of the filter cake can be substantially increased using the hydrosoft process; only the pump system must be retrofitted. As a preliminary measure, tests with mobile pilot plants should be carried out. (orig.) [German] Mit dem Hydrosoft-Verfahren besteht die Moeglichkeit Schlaemme, insbesondere auch Schlaemme aus kommunalen Klaeranlagen, auf hohe Trockensubstanz-Gehalte zu entwaessern. Auch bei bestehenden Entwaesserungsanlagen, die mit den langlebigen Kammerfilterpressen ausgeruestet sind, koennen die Trockensubstanzgehalte der Filterkuchen mit dem Hydrosoft-Verfahren, fuer das dann nur noch das Pumpsystem nachgeruestet werden muss, wesentlich angehoben werden. Vorausgehen sollten jeweils Vorversuche mit mobilen Versuchsanlagen. (orig.)

  1. Contribution of occupational therapy for patients with depression / Beitrag der Ergotherapie in der Wahrnehmung von Menschen mit Depression

    Directory of Open Access Journals (Sweden)

    Treusch Yvonne

    2016-12-01

    Full Text Available In Bezug auf den professionellen Beitrag und die Wirkfaktoren der Ergotherapie bei Menschen mit Depression existieren bislang wenige Studien. Dies steht im Kontrast zum praktischen und quantitativen Beitrag dieser Therapieform.

  2. A review of the MIT experiments on the closed-loop digital control of reactor power

    International Nuclear Information System (INIS)

    Bernard, J.A.

    1989-01-01

    In this paper a review is provided of certain major experiments conducted from 1985 to 1988 as part of the MIT program on the development and demonstration of advanced technologies for the closed-loop digital control of nuclear reactors. Included are demonstrations of the supervisory control of neutronic power using an alternate formulation of the dynamic period equation, the use of the MIT-SNL Period-Generated Minimum Time Control Laws for the time-optimal control of neutronic power, and the evaluation of predictive displays as an operator aid. The significance of each of these advances is discussed in terms of the overall development of a multi-tiered controller that includes supervisory algorithms, predictive control laws, and automated reasoning

  3. Rethinking the Relationship Between Academia and Industry: Qualitative Case Studies of MIT and Stanford.

    Science.gov (United States)

    Zhu, Fengliang; Hawk, Soaring

    2016-10-01

    As knowledge has become more closely tied to economic development, the interrelationship between academia and industry has become stronger. The result has been the emergence of what Slaughter and Leslie call academic capitalism. Inevitably, tensions between academia and industry arise; however, universities such as MIT and Stanford with long traditions of industry interaction have been able to achieve a balance between academic and market values. This paper describes the strategies adopted by MIT and Stanford to achieve this balance. The results indicate that implicit culture is a stronger determinant of balance than are explicit rules. Finally, the author proposes a concept of balance to reconsider the relationship between academia and industry: today's universities, particularly those with strengths in engineering and management, are both symbiotic and interdependent with industry. A reasonable attitude toward the university-industry relationship is that of balance rather than strict separation. Universities can thus establish effective mechanisms to reach a balance between conflicting values.

  4. Coupling of the Magnetosphere-Ionosphere/Thermosphere and Oxygen Outflow-- MIT Mission

    Science.gov (United States)

    Fu, S.

    2017-12-01

    The goal of the MIT mission is to understand the coupling of the magnetosphere and ionosphere from the prospective of particles. It will focus on the outflow of the ionosphere particles (mainly oxygen ions) from the Earth, including the acceleration mechanisms of oxygen ions and their relative importance in different regions, the importance of these ions while transferred into the magnetosphere and the roles they played in magnetosphere activities. A constellation of four satellites orbiting at three elliptical orbits will provide the unique opportunities to observed there ions at three different altitude with temporal changes of the flux of these particles and the magnetic field environments. The conceptual design of the spacecraft and a summary of the payload will be presented. The MIT mission was selected as one of the five candidates for the upcoming mission plan in China.

  5. A Systems Approach to Healthcare Innovation Using the MIT Hacking Medicine Model.

    Science.gov (United States)

    Gubin, Tatyana A; Iyer, Hari P; Liew, Shirlene N; Sarma, Aartik; Revelos, Alex; Ribas, João; Movassaghi, Babak; Chu, Zen M; Khalid, Ayesha N; Majmudar, Maulik D; Lee, Christopher Xiang

    2017-07-26

    MIT Hacking Medicine is a student, academic, and community-led organization that uses systems-oriented "healthcare hacking" to address challenges around innovation in healthcare. The group has organized more than 80 events around the world that attract participants with diverse backgrounds. These participants are trained to address clinical needs from the perspective of multiple stakeholders and emphasize utility and implementation viability of proposed solutions. We describe the MIT Hacking Medicine model as a potential method to integrate collaboration and training in rapid innovation techniques into academic medical centers. Built upon a systems approach to healthcare innovation, the time-compressed but expertly guided nature of the events could enable more widely accessible preliminary training in systems-level innovation methodology, as well as creating a structured opportunity for interdisciplinary congregation and collaboration. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. KoelnArena has 18,000 seats; Die KoelnArena mit 18 000 Sitzplaetzen

    Energy Technology Data Exchange (ETDEWEB)

    Zerres, E.

    1999-06-01

    The ``Koelnarena`` is a new hall with 18,000 seats for sports events and cultural events, and with a skating rink in the hall center. In view of the many events (up to 180 per year), the skating rink must be glazed throughout the year (except for the summer holidays) in order to avoid the high cost of frequent freezing and thawing. [Deutsch] Die Koelnarena ist eine neue Halle fuer 18 000 Besucher in Koeln-Deutz, mit vielfacher Verwendbarkeit fuer Eishockey und Eistanz, Tennis, Volleyball, Boxen, Schausport, Showkonzerte, Oper und Tanzveranstaltungen. Das Kernstueck dieser MEGA-Halle ist die Eispiste in der Hallenmitte. Wegen der hohen Auslastung der Halle mit bis zu 180 Veranstaltungen pro Jahr muss die Eispiste ganzjaehrig (ausser waehrend der Sommerferien) vereist bleiben, um den sehr grossen Energieaufwand fuer haeufig Eisbildung (und Abtauen.) sowie die Kosten hierfuer zu vermeiden. (orig.)

  7. Center for Multiscale Plasma Dynamics: Report on Activities (UCLA/MIT), 2009-2010

    Energy Technology Data Exchange (ETDEWEB)

    Carter, Troy Alan [Univ. of California, Los Angeles, CA (United States)

    2014-10-03

    The final “phaseout” year of the CMPD ended July 2010; a no cost extension was requested until May 2011 in order to enable the MIT subcontract funds to be fully utilized. Research progress over this time included verification and validation activities for the BOUT and BOUT++ code, studies of spontaneous reconnection in the VTF facility at MIT, and studies of the interaction between Alfv´en waves and drift waves in LAPD. The CMPD also hosted the 6th plasma physics winter school in 2010 (jointly with the NSF frontier center the Center for Magnetic Self-Organization, significant funding came from NSF for this most recent iteration of theWinter School).

  8. Educational Outreach at the M.I.T. Plasma Fusion Center

    Science.gov (United States)

    Censabella, V.

    1996-11-01

    Educational outreach at the MIT Plasma Fusion Center consists of volunteers working together to increase the public's knowledge of fusion and plasma-related experiments. Seeking to generate excitement about science, engineering and mathematics, the PFC holds a number of outreach activities throughout the year, such as Middle and High School Outreach Days. Outreach also includes the Mr. Magnet Program, which uses an interactive strategy to engage elementary school children. Included in this year's presentation will be a new and improved C-MOD Jr, a confinement video game which helps students to discover how computers manipulate magnetic pulses to keep a plasma confined for as long as possible. Also on display will be an educational toy created by the Cambridge Physics Outlet, a PFC spin-off company. The PFC maintains a Home Page on the World Wide Web, which can be reached at http://cmod2.pfc.mit.edu/.

  9. Geschmackspapillendichte und Geschmackswahrnehmung bei Jugendlichen mit Essstörungen und einer gesunden Kontrollgruppe

    OpenAIRE

    Kaltenhofer, Alice

    2009-01-01

    Fragestellung Die Schmeckwahrnehmung wird u.a. über Lernprozesse, kognitive Vorgänge, genetische und biochemische Faktoren reguliert. Ess- und Diätverhalten werden durch sie beeinflusst. Den anatomisch und physiologisch ersten Abschnitt der Schmeckwahrnehmung bilden die fungiformen Geschmackspapillen. In den Geschmackspapillen liegen die Geschmacksknopsen, mit deren Hilfe die Schmeckstoffe aufgenommen und in Form von Aktionspotentialen zum Thalamus, dem limbischen System,dem Gyrus postzentral...

  10. Calculations of higher twist distribution functions in the MIT bag model

    International Nuclear Information System (INIS)

    Signal, A.I.

    1997-01-01

    We calculate all twist-2, -3 and -4 parton distribution functions involving two quark correlations using the wave function of the MIT bag model. The distributions are evolved up to experimental scales and combined to give the various nucleon structure functions. Comparisons with recent experimental data on higher twist structure functions at moderate values of Q 2 give good agreement with the calculated structure functions. (orig.)

  11. Einsatzverhalten genuteter CBN-Schleifscheiben mit keramischer Bindung beim Außenrund-Einstechschleifen

    OpenAIRE

    Kirchgatter, Mathias

    2010-01-01

    Industrielle Schleifprozesse für Bauteile aus gehärteten Stahlwerkstoffen werden vermehrt mit keramisch gebundenen CBN-Schleifscheiben durchgeführt, die sich bei vielen Anwendungen aufgrund ihres Eigenschaftsprofils und der erweiterten Einstellbarkeit der Bindungsspezifikationen gegenüber anderen Schleifwerkzeugtypen durchsetzen. Der Optimierungsdruck der Großserien- und Massenfertigungsprozesse hat bereits zu einer beachtlichen Entwicklung hinsichtlich der Leistungsfähigkeit dieses Werkzeugt...

  12. Hardware for quasi-single-shot multifrequency magnetic induction tomography (MIT): the Graz Mk2 system

    International Nuclear Information System (INIS)

    Scharfetter, H; Köstinger, A; Issa, S

    2008-01-01

    Magnetic induction tomography (MIT) has been suggested by several groups for the contact-less mapping of the passive electrical properties of tissues via AC magnetic fields in the frequency range between several tens of kHz and several tens of MHz. Multifrequency MIT as an analog to multifrequency EIT has been tried and first image reconstructions have been demonstrated with phantoms. MIT appears to yield comparable images to EIT but offers the advantage of being non-contacting. In the beta-dispersion range of most tissues the method is challenging because the signals are very small and buried in noise. In order to minimize drifts and systematic errors fast data acquisition is therefore pivotal. This paper presents a method for single-shot MIT which allows us to acquire the data for a multifrequency image with an analog bandwidth of 50 kHz–1.5 MHz which covers a good part of the β-dispersion of many tissues. The transmit (TX) coils are simultaneously driven by individual power amplifiers with a multisinus pattern with up to 3 A pp . The amplifiers are configured as current sources so as not to perturb the excitation fields by inappropriately terminated coils. The separation of the different TX channels after reception is achieved by splitting up the carrier frequencies into individual subcarriers with a narrow spacing of at most 300 Hz. In this way every TX coil is identifiable by its own subcarrier but the whole excitation band is contained within a few kHz. The real and imaginary parts of the received signals are extracted efficiently with FFT. The system noise and the sources for low-frequency perturbations are analyzed and characterized

  13. MIT Laboratory for Computer Science Progress Report No. 23, July 1985-June 1986

    Science.gov (United States)

    1986-06-01

    34An Expert System for Diagnosing Gait in Cerebral Palsy Patients," S.M. thesis, MIT Department of Electrical Engineering and Computer Science, Cambridge...barriers to program interoperability. Within our community, we perceive serious problems in building on the work of others, because the different...unmatched tokens. Of course, the name of the game is representation and access to the various data structures, and this has worked out very nicely. GITA

  14. Pionic corrections to the MIT bag model: The (3,3) resonance

    International Nuclear Information System (INIS)

    Theberge, S.; Thomas, A.W.; Miller, G.A.

    1980-01-01

    By incorporating chiral invariance in the MIT bag model, we are led to a theory in which the pion field is coupled to the confined quarks only at the bag surface. An equivalent quantized theory of nucleons and Δ's interacting with pions is then obtained. The pion-nucleon scattering amplitude in this model is found to give a good fit to experimental data on the (3,3) resonance, with a bag radius of about 0.72 fm

  15. An Approach for Prevention of MitM Attack Based on Rogue AP in Wireless Network

    OpenAIRE

    Zhendong Wu; Mengru Cai; Siyu Liang

    2014-01-01

    With the rapid development of WLAN, more and more schools and businesses have begun to provide the WLAN for users. However, WLAN is considerably more susceptible to MitM (man- in-the-middle) attack. To overcome it, we propose a dynamic password technology named Two-way Dynamic Authentication Technology (TDAT). It uses two-factor during the initial authentication, and uses a two-way hash chain during the cross-domain authentication. TDAT effectively protects users' authentication credentials a...

  16. Psychologie körperlicher Aktivität bei Patienten mit Rückenschmerzen

    OpenAIRE

    Leonhardt, Corinna

    2008-01-01

    Die vorliegende Arbeit setzt sich mit den psychologischen Determinanten und Fördermöglichkeiten von körperlicher Aktivität bei Rückenschmerzpatienten auseinander, wobei Daten einer multizentrischen cluster-randomisierten Studie (N= 1378) genutzt werden. Der theoretische Hintergrund aller Originalarbeiten gibt einen Überblick zu neuen Erkenntnissen zum Rückenschmerz und zur Aktivitätsförderung in der Gesundheitspsychologie und ...

  17. The neurosciences research program at MIT and the beginning of the modern field of neuroscience.

    Science.gov (United States)

    Adelman, George

    2010-01-15

    The interdisciplinary field, "neuroscience," began at MIT in 1962 with the founding of the Neurosciences Research Program (NRP) by Francis O. Schmitt and a group of US and international scientists - physical, biological, medical, and behavioral - interested in understanding the brain basis of behavior and mind. They organized and held specialist meetings of basic topics in neuroscience, and the journal and book publications over the next 20 years, based on these meetings, helped establish the new field.

  18. Schlafmedizinische Charakterisierung von Parkinson-Patienten mit Schlafattacken unter dopaminerger Therapie

    OpenAIRE

    Rethfeldt, Mira

    2006-01-01

    1999 wurden erstmals sogenannte Schlafattacken bei Parkinson-Patienten unter der Therapie mit Nonergolin-Dopaminagonisten berichtet. Später zeigten Studien, dass diese Schlafattacken unter jeglicher dopaminerger Therapie auftreten können. Bis heute ist jedoch die Pathophysiologie dieses Phänomens nicht hinreichend geklärt. Es wird diskutiert, ob diese Attacken als paroxysmales Symptom überhaupt bestehen oder nicht vielmehr ...

  19. Zielgerichtete Chemotherapie solider Tumoren durch thermosensitive Liposomen in Kombination mit Doxorubicin, Gemcitabin und Mitomycin C

    OpenAIRE

    Limmer, Simone

    2014-01-01

    Auf DPPG2 basierende thermosensitive Liposomen (TSL) mit Hyperthermie (HT) induzierter zielgerichteter Wirkstofffreisetzung sind eine viel-versprechende Behandlungsstrategie in der Krebstherapie. TSL können als Wirkstoffträgersysteme die Zirkulationszeit und Anreicherung von Wirkstoffen im Zielgewebe erhöhen. Die vielfältigen Krebserkrankungen zeigen unterschiedliches Tumoransprechen auf die routinemäßig eingesetzten Zytostatika. Daher wäre es vorteilhaft, verschiedene Wirkstoffe in TSL e...

  20. Verhaltenstherapie bei Enkopresis am Beispiel einer Patientin mit chronischem "Toiletten-Verweigerungssyndrom"

    OpenAIRE

    Hansen, Berit; Lehmkuhl, Ulrike

    2007-01-01

    Enkopresis gehört zu den wenig beforschten psychischen Störungen im Kindes- und Jugendalter. Auch Literatur zur psychotherapeutischen Behandlung der Störung findet man kaum. Das verhaltenstherapeutische Standardbehandlungsvorgehen soll beschrieben und anhand eines ausführlichen Fallbeispiels eines 7,9-jährigen Mädchens mit "Toilettenverweigerungssyndrom" erläutert werden. Schlagwörter Verhaltenstherapie - Kindesalter - Enkopresis- "Toilettenverweigerungssyndrom" Encopresis is one of...

  1. Neuropsychologische Aspekte der Diagnostik von Kindern mit umschriebenen Entwicklungsstörungen schulischer Fertigkeiten

    OpenAIRE

    Blender, Anja

    2004-01-01

    Die vorliegende Studie liefert empirische Evidenz für die Annahme von umschriebenen Entwicklungsstörungen schulischer Fertigkeiten als Manifestation einer auffälligen neuropsychologischen Entwicklung. Von allen untersuchten neuropsychologischen Funktionen erwies sich die phonologische Verarbeitung, insbesondere die phonologische Bewusstheit, als die am höchsten diskriminative Variable für umschriebene Lernstörungen im Lesen und/ oder Rechtschreiben sowie in der kombinierten Form mit Rechenstö...

  2. Trennung und Rekombination von Ladungsträgern in Solarzellen mit nanostrukturierter ZnO-Elektrode

    OpenAIRE

    Tornow, Julian

    2010-01-01

    In dieser Arbeit werden Elektroden aus hydrothermal auf leitfähigem Glassubstrat (Leitglas) abgeschiedenen ZnO-Nanostangen betrachtet. Die Elektroden selbst sind für sichtbares Licht transparent und werden für eine Anwendung als Solarzelle mit einer lichtabsorbierenden Schicht sensibilisiert; hier sind das entweder metallorganische Farbstoffmoleküle (N3) oder eine nur wenige Nanometer dicke Schicht aus Indiumsulfid. Für die elektrische Kontaktierung der sensibilisierten Elektrode wird entwed...

  3. La France au Tsar : chanson patriotique créée par Marius Richard à la Scala, Henri Helme à Ba-ta-clan [illustration couleurs Donjean

    OpenAIRE

    François Bigot Éditeur , .; Daphy , Éliane

    2010-01-01

    La France au Tsar : chanson patriotique créée par Marius Richard à la Scala, Henri Helme à Ba-ta-clan ; paroles de Lucien Colonge, Musique de J. Claudel. [Illustration couleurs signée] Donjean. A la chanson populaire, Maison Bigot éditeur (sans cotage, sans ©, datation recherche en cours). Titre inconnu du catalogue BNF. Datation provisoire par année de dépôt médihal (2010)

  4. Gasification together with other residual materials; Vergasung gemeinsam mit anderen Reststoffen

    Energy Technology Data Exchange (ETDEWEB)

    Lungwitz, H. [Berliner Wasserbetriebe, Berlin (Germany)

    1998-09-01

    The commonest method of thermal sewage sludge treatment at present is still combustion in mono-fluidised-bed plants. The possibilities described in the introduction of this paper give an impression of the great variety of disposal methods with a thermal final stage among which one can choose today. The solution that has been found to the disposal problems of four sewage plants in Berlin shows by way of example how a Europe-wide tender can lead to an inexpensive, permanent, secure, and flexible disposal system which includes recycling and figures as part of an integrated disposal system for different wastes. This disposal system has found ready acceptance on account of its environmental friendliness and sparing consumption of resources. Unlike incineration plants, its construction did not meet with public resistance. [Deutsch] Die zur Zeit noch haeufigste thermische Klaerschlammbehandlung ist die Verbrennung in Mono-Wirbelschichtanlagen. Die einleitend geschilderten Moeglichkeiten lassen jedoch die Vielfalt erkennen, die jetzt bei der Wahl eines Entsorgungsweges mit thermischer Endstufe gegeben sind. Die Loesung der Entsorgungsprobleme fuer 4 Berliner Klaerwerke hat beispielhaft gezeigt wie z.B. mittels eines europaweiten Ausschreibungsverfahrens ein kostenguenstiger, zeitlich nicht begrenzter, sicherer und flexibler Entsorgungsweg mit stofflicher Verwertung im Rahmen eines Verbundkonzeptes mit anderen Abfallstoffen gefunden werden kann. Ein Verwertungsweg, der allgemein wegen seiner Umweltvertraeglichkeit und Ressourcenschonung grosse Akzeptanz erfahren hat. Widerstand, wie beim Bau von Verbrennungsanlagen, hat es nicht gegeben. (orig.)

  5. [COPD und Klangtherapie: Pilotstudie zur Wirksamkeit einer Behandlung mit Körpertambura bei COPD-Patienten].

    Science.gov (United States)

    Hartwig, Bernhard; Schmidt, Stefan; Hartwig, Isabella

    2016-01-01

    Hintergrund: Erkrankungen der Atemorgane treten mit steigendem Alter öfter auf, nehmen weltweit zu und sind häufige Ursachen für Morbidität und Mortalität. In dieser Pilotstudie wurde der Frage nachgegangen, ob eine einmalige 10-minütige Behandlung mit einer Körpertambura eine signifikante und effektive Verbesserung der Lungenfunktion von Patienten mit chronisch-obstruktiver Lungenerkrankung (COPD; GOLD-Stadium A oder B) erbringen kann. Patienten und Methoden: 54 Probanden konnten je zur Hälfte in eine Behandlungsgruppe (Körpertambura) und eine aktive Kontrollgruppe (Atemtherapie) randomisiert werden. Eine Bestimmung der Lungenfunktionsmessparameter «Einsekundenkapazität» (FEV1) und «inspiratorische Vitalkapazität» (IVC) zu den Zeitpunkten T1 (Baseline), T2 (direkt nach Behandlung) und als Follow-up etwa 3 Wochen nach T1 (T3). Ergebnisse: Die Behandlungsgruppe zeigte sich der Kontrollgruppe in beiden Werten signifikant überlegen. Die Zeit-×-Gruppe-Interaktion (Varianzanalyse) ergab p = 0,001 (FEV1) bzw. p = 0,04 (IVC). Die Behandlungsgruppe zeigte bei beiden Werten eine Verbesserung von klinischer Relevanz. Schlussfolgerung: Diese Ergebnisse zeigen, dass die Klangbehandlung mittels einer Körpertambura - neben den schulmedizinischen, leitliniengerechten Therapien - eine zusätzliche, nebenwirkungsarme, aber durchaus klinisch wirksame Option für die Behandlung von COPD-Patienten darstellen kann, um deren Lebensqualität zu stabilisieren und zu verbessern. © 2016 S. Karger GmbH, Freiburg.

  6. A metabolic signature for long life in the Caenorhabditis elegans Mit mutants.

    Science.gov (United States)

    Butler, Jeffrey A; Mishur, Robert J; Bhaskaran, Shylesh; Rea, Shane L

    2013-02-01

    Mit mutations that disrupt function of the mitochondrial electron transport chain can, inexplicably, prolong Caenorhabditis elegans lifespan. In this study we use a metabolomics approach to identify an ensemble of mitochondrial-derived α-ketoacids and α-hydroxyacids that are produced by long-lived Mit mutants but not by other long-lived mutants or by short-lived mitochondrial mutants. We show that accumulation of these compounds is dependent on concerted inhibition of three α-ketoacid dehydrogenases that share dihydrolipoamide dehydrogenase (DLD) as a common subunit, a protein previously linked in humans with increased risk of Alzheimer's disease. When the expression of DLD in wild-type animals was reduced using RNA interference we observed an unprecedented effect on lifespan - as RNAi dosage was increased lifespan was significantly shortened, but, at higher doses, it was significantly lengthened, suggesting that DLD plays a unique role in modulating length of life. Our findings provide novel insight into the origin of the Mit phenotype. © 2012 The Authors Aging Cell © 2012 Blackwell Publishing Ltd/Anatomical Society of Great Britain and Ireland.

  7. Clinical accuracy of inflationary oscillometry in pregnancy and pre-eclampsia: Omron-MIT Elite.

    Science.gov (United States)

    Chung, Y; Brochut, M C; de Greeff, A; Shennan, A H

    2012-10-01

    To evaluate the accuracy of the Omron MIT Elite in pregnancy and pre-eclampsia according to the British Hypertension Society protocol (BHS). Prospective observational study. Antenatal clinics and wards at St. Thomas' Hospital (London, UK). Forty-five pregnant women including 15 with pre-eclampsia. Nine sequential same arm blood pressure (BP) measurements were taken from each woman by trained observers, alternating between mercury sphygmomanometry and the test device. Grading criteria of the BHS protocol (A/B grade=pass; C/D=fail). The Omron MIT Elite achieved a grade A/A in both pregnancy and pre-eclampsia. The mean difference (SD) between the mercury standard and the device in pregnancy was -1.1 (5.2)mmHg and 1.5 (4.8)mmHg for systolic and diastolic BP respectively compared to 0.2 (5.3)mmHg and 2.2 (5.5)mmHg in pre-eclampsia. The Omron MIT Elite can be recommended for use in pregnancy and pre-eclampsia according to the BHS protocol. To date, this is the most accurate automated BP device validated in pre-eclampsia. Copyright © 2012. Published by Elsevier B.V.

  8. [Homöopathisch-phytotherapeutische Behandlung des Reizdarmsyndroms mit Magen-Darm-Entoxin N®: Eine Anwendungsbeobachtung].

    Science.gov (United States)

    Märtens, Diane; Range, Natasha; Günnewich, Nils; Gruber, Nicola; Schmidt, Stefan

    Hintergrund: In dieser Anwendungsbeobachtung wird zum ersten Mal die Behandlung des Reizdarmsyndroms (RDS) mit einem homöopathisch-phytotherapeutischen Komplexpräparat beschrieben. Methodik: Ziel der 6-wöchigen Therapie mit dem Magen-Darm-Entoxin N® war die Reduzierung der RDS-Symptomatik sowie die Verbesserung der Lebensqualität. Zielkriterien waren die Veränderungen in der Irritable Bowel Syndrome - Severity Scoring System (IBS-SSS) und der Irritable Bowel Syndrome - Quality-of-Life Scale (IBS-QoL). Die Patient/innen (N = 41; Alter 44,0 ± 15,74 Jahre) wurden zu gleichen Teilen in einer Hausarztpraxis (N = 20) und einer Heilpraktikerpraxis (N = 21) rekrutiert. Ergebnisse: Der IBS-QoL-Score verringerte sich signifikant (prä: 35,9 ± 16,3; post: 20,1 ± 13,4; t = 8,504; p mit einer Effektstärke von d = 1,24. Die Neben- und Wechselwirkungen waren minimal und signifikante Unterschiede zwischen beiden Praxen wurden nicht gefunden. Schlussfolgerungen: Magen-Darm-Entoxin N® ist eine sichere und sinnvolle Therapieoption bei der Behandlung des RDS. Allerdings sollten randomisierte kontrollierte Studien folgen, um die Spezifizität der Ergebnisse dieser Anwendungsbeobachtung zu stützen. © 2017 S. Karger GmbH, Freiburg.

  9. Embryonic expression of zebrafish MiT family genes tfe3b, tfeb, and tfec.

    Science.gov (United States)

    Lister, James A; Lane, Brandon M; Nguyen, Anhthu; Lunney, Katherine

    2011-11-01

    The MiT family comprises four genes in mammals: Mitf, Tfe3, Tfeb, and Tfec, which encode transcription factors of the basic-helix-loop-helix/leucine zipper class. Mitf is well-known for its essential role in the development of melanocytes, however the functions of the other members of this family, and of interactions between them, are less well understood. We have now characterized the complete set of MiT genes from zebrafish, which totals six instead of four. The zebrafish genome contain two mitf (mitfa and mitfb), two tfe3 (tfe3a and tfe3b), and single tfeb and tfec genes; this distribution is shared with other teleosts. We present here the sequence and embryonic expression patterns for the zebrafish tfe3b, tfeb, and tfec genes, and identify a new isoform of tfe3a. These findings will assist in elucidating the roles of the MiT gene family over the course of vertebrate evolution. Copyright © 2011 Wiley-Liss, Inc.

  10. A METABOLIC SIGNATURE FOR LONG-LIFE IN THE C. ELEGANS MIT MUTANTS

    Science.gov (United States)

    Butler, Jeffrey A.; Mishur, Robert J.; Bhaskaran, Shylesh; Rea, Shane L.

    2012-01-01

    SUMMARY Mit mutations that disrupt function of the mitochondrial electron transport chain can, inexplicably, prolong Caenorhabditis elegans lifespan. In this study we use a metabolomics approach to identify an ensemble of mitochondrial-derived α-ketoacids and α-hydroxyacids that are produced by long-lived Mit mutants but not by other long-lived mutants or by short-lived mitochondrial mutants. We show that accumulation of these compounds is dependent upon concerted inhibition of three α-ketoacid dehydrogenases that share dihydrolipoamide dehydrogenase (DLD) as a common subunit, a protein previously linked in humans with increased risk of Alzheimer’s disease. When the expression of DLD in wild type animals was reduced using RNA interference we observed an unprecedented effect on lifespan - as RNAi dosage was increased lifespan was significantly shortened but, at higher doses, it was significantly lengthened, suggesting DLD plays a unique role in modulating length of life. Our findings provide novel insight into the origin of the Mit phenotype. PMID:23173729

  11. Untersuchung perturbativer und nichtperturbativer Struktur der Momente hadronischer Ereignisformvariablen mit den Experimenten JADE und OPAL

    CERN Document Server

    Pahl, Christoph Johannes

    2007-01-01

    In Hadronproduktionsdaten der e+e− - Vernichtungsexperimente JADE und OPAL messen wir die ersten f¨unf Momente von zw¨olf hadronischen Ereignisformvariablen bei Schwerpunktsenergien von 14 bis 207GeV. Aus dem Vergleich der QCD NLO-Vorhersage mit den mittels MC-Modellen um Hadronisierung korrigierten Daten erhalten wir den Referenzwert der starken Kopplung αs(MZ0) = 0.1254 ± 0.0007(stat.) ± 0.0010(exp.)+0.0009 −0.0023(had.)+0.0069 −0.0053(theo.) . F¨ur einige, insbesondere h¨ohere, Momente sind systematische Unzul¨anglichkeiten in der QCD NLO-Vorhersage erkenntlich. Simultane Fits an zwei Momente unter Annahme identischer Renormierungsskalen ergeben Skalenwerte von xμ=0.057 bis xμ=0.196 . Wir pr¨ufen Vorhersagen verschiedener nichtperturbativer Modelle. Aus der Single Dressed Gluon - N¨aherung ergibt sich eine perturbative Vorhersage in O(α5 s ) mit zu vernachl¨assigender Energiepotenzkorrektur, die den Mittelwert von Thrust auf Hadronniveau gut beschreibt mit αs(MZ0) = 0.1186 ± 0.0007(st...

  12. Problembasiertes kollaboratives Lernen mit virtuellen Patienten in der Kinderheilkunde: ein Beispiel aus der Ausbildungspraxis

    Directory of Open Access Journals (Sweden)

    Sostmann, Kai

    2009-02-01

    Full Text Available Der studentische Unterricht in der Kinderheilkunde an der Charité hat seit 1999 mehrere Umstrukturierungen durchlaufen. Mit der Einführung der neuen ärztlichen Approbationsordnung 2004 im Regelstudiengang (RSG und dem Modellcurriculum Reformstudiengang Medizin (RSM 1999 müssen zwei Curricula parallel neu konzipiert und gepflegt werden. Durch den Schwerpunkt Unterricht am Krankenbett (UaK im RSG ergaben sich neue didaktische, pädagogische und infrastrukturelle Anforderungen. Die technische und inhaltliche Weiterentwicklung der Einsatzmöglichkeiten elektronischer Lernszenarien durch e-Learning im Rahmen des BMBF-geförderten Projektes ELWIS-MED, ermöglichte die Erprobung der curricularen Implementierung von e-Learning-Modulen im Pflichtunterricht. Der UaK wurde durch die Bearbeitung kinderheilkundlicher elektronischer Lernfälle online ergänzt. Die Studierenden sollten tutoriell betreute Diskussionen zu fachlichen Aufgabenstellungen online führen. In der ersten Erprobungsstufe wurde der Einsatz der Diskussionsforen in Verbindung mit den Lernfällen von den Studierenden und Lehrenden als sinnvolle Ergänzung betrachtet. In zukünftigen Einsatzszenarien sollte eine Messung des studentischen Lernerfolgs mit dieser Methode erfolgen.

  13. Magnetisches Tracking für die Navigation mit dem da Vinci® Surgical System

    Science.gov (United States)

    Nickel, Felix; Wegner, Ingmar; Kenngott, Hannes; Neuhaus, Jochen; Müller-Stich, Beat P.; Meinzer, Hans-Peter; Gutt, Carsten N.

    In dieser Studie wurde untersucht ob in einem typischen OP-Aufbau mit dem da Vinci® Telemanipulator elektromagnetisches Tracking für die Realisation eines Navigationssystems eingesetzt werden kann. Hierfür wurde in einem realen OP-Aufbau untersucht, wie stark metallische und ferromagnetisch wirksame Objekte wie Operationstisch und Telemanipulator das elektromagnetische Feld des Trackingsystems beeinflussen. Die Ergebnisse zeigen, dass der Telemanipulator nur unwesentlich die Störung des Magnetfeldes durch den OP-Tisch verstärkt. Insbesondere die Bewegung der Instrumente im Trackingvolumen verursachte keine zusätzliche relevante Störung des Magnetfeldes. Bei Begrenzung des Trackingvolumens auf eine Länge von 190 mm, Höhe von 200mm und Breite von 400 mm war der maximale Fehler in diesem Bereich an allen Messpunkten kleiner 10 mm. Der Einsatz von elektromagnetischem Tracking für die Navigation mit dem da Vinci® Surgical System ist somit in einem begrenzten Arbeitsvolumen mit hinreichender Genauigkeit möglich.

  14. Design of a propeller turbine with a variable revolution number; Entwicklung einer Propellerturbine mit variabler Drehzahl

    Energy Technology Data Exchange (ETDEWEB)

    Fella, G.; Wierer, C. [Fella GmbH Maschinen- und Apparatebau, Amorbach (Germany); Goede, E.; Batrekhy, S.; Ruprecht, A. [Stuttgart Univ. (Germany). Inst. fuer Stroemungsmechanik und Hydraulische Stroemungsmaschinen

    1997-12-31

    The small hydroelectric power station of Rupboden in the Oberfranken district was reactivated after having been decommissioned for 30 years. This new low pressure plant consists of an open-flume turbine with an adjustable diffusor and a firm rotor disk (propeller) with a vertical rod. A large range of operation at a constant height of fall is ensured by a variable revolution number. The profiles of the adjustable diffusor and rotor disk and the design of the draft tube were optimized using numerical flow calculation. First operating experience is very positive. The turbine runs extremely smoothly over the entire range. (orig.) [Deutsch] Das Kleinwasserkraftwerk Rupboden in Oberfanken wurde nach 30 Jahren Stillstand reaktiviert. Die neue Niederdruckanlage besteht aus einer Schachtturbine mit verstellbarem Leitapparat, feststehendem Laufrad (Propeller) mit senkrechter Welle. Zum Erzielen eines grossen Betriebsbereiches bei gleichbleibender Fallhoehe wurde eine variable Drehzahl vorgesehen. Die Profilierung von Leitapparat und Laufrad sowie die Formgebung fuer das Saugrohr wurden mit numerischer Stroemungsberechnung optimiert. Erste Betriebserfahrungen sind sehr positiv. Die Turbine laeuft im gesamten Leistungsbereich ausserordentlich ruhig. (orig.)

  15. Axial turbine with underwater generator for energy recovery; Axialturbine mit Unterwassergenerator zur Energierueckgewinnung

    Energy Technology Data Exchange (ETDEWEB)

    Welzel, B. [Stuttgart Univ. (Germany). Inst. fuer Stroemungsmechanik und Hydraulische Stroemungsmaschinen

    1997-12-31

    Within the framework of a project sponsored by the Stiftung Energieforschung Baden-Wuerttemberg, an axial turbine was developed as a flash evaporator, which permits energy recovery in all sectors where liquids in piping undergoes pressure relaxation. A specific feature of this turbine is that it forms part, complete with generator, of a single pipeline and that it does not cause any pressure variations worth mentioning in case of mains failure. The report describes the turbine, its advantages, and a pilot operation carried out with a prototype. The turbine`s performance is compared with a return pump. Further, the optimization of the hydraulic design by computer and the results of a market analysis are dealt with. (orig.) [Deutsch] Im Rahmen einer von der Stiftung Energieforschung Baden-Wuerttemberg gefoerderten Neuentwicklung wurde eine Axialturbine als Entspannungsturbine entwickelt, mit der eine Energierueckgewinnung in allen Bereichen erfolgen kann, in denen Fluessigkeiten in Rohrleitungssystemen entspannt werden. Die Turbine zeichnet sich unter anderem dadurch aus, dass sie komplett, inklusive Generator, innerhalb einer Rohrleitung angeordnet ist und bei Netzausfall keine nennenswerte Druckschwankung erzeugt. Es werden die Turbine, deren Vorteile sowie der mit einem Prototypen durchgefuehrte Betriebsversuch beschrieben. Weiterhin werden ein Vergleich des Betriebsverhaltens mit einer rueckwaertslaufenden Pumpe, die rechnerische Optimierung der hydraulischen Formgebung sowie die Ergebnisse einer Marktanalyse behandelt. (orig.)

  16. Automatizace MitM útoku pro dešifrování SSL/TLS

    OpenAIRE

    Marušic, Marek

    2016-01-01

    Protokoly SSL/TLS sú používané pre šifráciu sieťovéhej prevádzky. Poskytujú bezpečnú komunikáciu medzi klientmi a servermi. Komunikácia môže byť odpočúvaná pomocou MitM útoku. Táto práca je zameraná na atuomatizovanie MitM útoku a demonštráciu jej výsledkov. Automatizáciou sa zjednoduší spustenie útoku bez nutnosti študovania rôznych manuálových stránok a aby sa používatelia vyhli pracnej konfigurácii MitM zariadenia a mohli jednoducho zachytiť a analyzovať SSL/TLS komunikáciu. Automatizácia ...

  17. A phase-I clinical trial for cranial BNCT at Harvard-MIT

    International Nuclear Information System (INIS)

    Busse, P.M.; Palmer, M.R.; Harling, O.K.

    2000-01-01

    Phase I trial designed to determine the maximum tolerable dose to normal tissue for cranial BNCT (Boron Neutron Capture Therapy) irradiations was recently completed at Harvard Medical School and MIT. Twenty-two subjects diagnosed with either glioblastoma multiforme or intracranial melanoma were treated between 1996 and 1999. Subjects received either one or two administrations of boronophenylalanine intravenously at doses between 250 and 350 mg/kg body weight, then exposed in one, two or three fields to epithermal neutrons at the MIT Research Reactor in one or two fractions. Over the course of the study, the maximum normal tissue dose target was increased from 8.8 to 14.2 RBE (Relative Biological Effectiveness) Gy in 10% increments. Subjects have been followed clinically and radiographically. Of those patients surviving beyond six months, no MRI (Magnetic Resonance Image) white-matter changes were observed and no long-term complications attributable to BNCT were evident. Tumor responses were observed, particularly with the melanoma subjects. With increasing doses, difficulties arose from long irradiation times (approximately 3 hours) and the emergence of acute reactions in the skin and mucosa. The trial was stopped in May 1999. Future trials will be initiated with the new high intensity, low background fission converter beam at MIT. (author)

  18. Natural gas engine concept with EZEV potential; Erdgasmotorkonzept mit EZEV-Potential

    Energy Technology Data Exchange (ETDEWEB)

    Maier, F.; Mueller, P.; Heck, E.; Langen, P. [BMW AG (Germany)

    1997-09-01

    The first natural gas vehicles form BMW are designed for arbitrary gasoline or natural gas operation. It is possible only to a limited extent to take advantage of the benefits of natural gas as a fuel as long as this is the case. An analysis was made to determine possible improvements in terms of fuel economy, emissions, full load and maximum exhaust gas temperatures through selective optimisation for exclusive natural gas operation. The results of this analysis have been used in the design of natural gas engines for mid-sized vehicles. Vehicle examinations in FTP75 confirm the existing potential for satisfying EZEV standards discussed in California even with vehicles of the upper midsize category by using optimised natural gas engines. (orig.) [Deutsch] Die ersten Automobile mit Erdgasantrieb von BMW sind fuer den wahlweisen Benzin- oder Erdgasbetrieb ausgelegt. Deshalb koennen die Vorteile des Kraftstoffs Erdgas nur zum Teil genutzt werden. Es wurde untersucht, welche Verbesserungen durch gezielte Optimierung fuer den ausschliesslichen Erdgasbetrieb bei Kraftstoffverbrauch, Emissionen, Vollast und maximalen Abgastemperaturen moeglich sind. Die Ergebnisse wurden bei der Auslegung von Erdgasmotoren fuer Mittelklassefahrzeuge verwendet. Untersuchungen im FTP-75 bestaetigen, dass mit optimierten Erdgasmotoren das Potential besteht, selbst mit Automobilen der oberen Mittelklasse die in Kalifornien diskutierten EZEV-Standards zu erfuellen. (orig.)

  19. Insight into the adsorption profiles of the Saprolegnia monoica chitin synthase MIT domain on POPA and POPC membranes by molecular dynamics simulation studies.

    Science.gov (United States)

    Kuang, Guanglin; Liang, Lijun; Brown, Christian; Wang, Qi; Bulone, Vincent; Tu, Yaoquan

    2016-02-21

    The critical role of chitin synthases in oomycete hyphal tip growth has been established. A microtubule interacting and trafficking (MIT) domain was discovered in the chitin synthases of the oomycete model organism, Saprolegnia monoica. MIT domains have been identified in diverse proteins and may play a role in intracellular trafficking. The structure of the Saprolegnia monoica chitin synthase 1 (SmChs1) MIT domain has been recently determined by our group. However, although our in vitro assay identified increased strength in interactions between the MIT domain and phosphatidic acid (PA) relative to other phospholipids including phosphatidylcholine (PC), the mechanism used by the MIT domain remains unknown. In this work, the adsorption behavior of the SmChs1 MIT domain on POPA and POPC membranes was systematically investigated by molecular dynamics simulations. Our results indicate that the MIT domain can adsorb onto the tested membranes in varying orientations. Interestingly, due to the specific interactions between MIT residues and lipid molecules, the binding affinity to the POPA membrane is much higher than that to the POPC membrane. A binding hotspot, which is critical for the adsorption of the MIT domain onto the POPA membrane, was also identified. The lower binding affinity to the POPC membrane can be attributed to the self-saturated membrane surface, which is unfavorable for hydrogen-bond and electrostatic interactions. The present study provides insight into the adsorption profile of SmChs1 and additionally has the potential to improve our understanding of other proteins containing MIT domains.

  20. Mit sprog - mit arbejde - mit liv

    DEFF Research Database (Denmark)

    Pedersen, Michael Svendsen

    2006-01-01

    Med inspiration fra et økologisk perspektiv på sproglæring diskuteres mulighederne for videreudvikling af en kommunikativ pædagogik inden for arbejdspladsrelateret undervisning i dansk som andetsprog for voksne....

  1. Leo Tolstoy, Mikhail Artsybashev, and Richard Wagner: About One Case of Polemics in Tolstoy’s The Circle of Reading

    Directory of Open Access Journals (Sweden)

    Anastasia A. Tulyakova

    2017-12-01

    Full Text Available The article deals with a case from the creative history of Leo Tolstoy’s The Circle of Reading (1908, when Tolstoy included the revised story of Guy de Maupassant’s Le Port under the title “Sisters” in the second edition of the book. The author proves that the reason for Tolstoy’s decision was his polemic with “saninstvo” as one of the most fashionable ethical trends of the first decade of the 1900s. The key component of Sanin’s behavior and hedonistic philosophy in Mikhail Artsybashev’s novel was incest. Maupassant’s novella is based on the same plot. On the basis of Tolstoy’s nonfictional texts of the 1890s, including the treatise What Is Art? (1898, the article reconstructs the writer’s view on the forms and boundaries of the representation of incest in Richard Wagner’s operas and in Friedrich Nietzsche’s philosophy, with which Tolstoy also polemicized and in connection with which he stated the ethical potential of art and its permissiveness. From this perspective, Tolstoy’s reaction to Artsybashev’s novel, combining the motives of incest and extreme individualism, turns out to be a new phase of the old dispute. Tolstoy included the story “Sisters” in the second edition of The Circle of Reading as a response to the philosophy of “saninstvo.” Thus, Tolstoy’s collection of wise thoughts can be considered not only as didactic, but also as a polemical text, and deeply rooted in the ideological context of the 1890s‒1900s.

  2. Funding Student Scholarships to the Richard Tapia Celebration of Diversity in Computing Conference 2013, February 7-10, 2013

    Energy Technology Data Exchange (ETDEWEB)

    Tapia, Richard

    2013-02-07

    This Basic Award allowed for the funding of student scholarships to the Richard Tapia Celebration of Diversity in Computing Conference which took place in Washington, D.C. from February 7-10, 2013. The conference was the seventh in a series and included a stellar array of invited speakers, compelling panel discussions, a student poster competition, a daylong Doctoral Consortium, a session featuring a choice of attractions unique to Washington, D.C., a gala banquet and dance, and many exciting networking opportunities. The conference created a welcoming environment for STEM students, especially underrepresented minority and female students, who were provided the highest quality of learning, networking, and social experiences to empower their educational experience and enhance their ability to succeed with a rigorous STEM degree. The networking and mentoring opportunities available at the conference were also designed to empower students to succeed in STEM careers and ultimately serve in leadership in industry and the professoriate. A key step in attracting underrepresented students into STEM fields and paving the way for their success in influential positions is to create a nurturing and supportive network and community for them to rely upon. It is also critical to educate leaders in corporations, government and academia about the benefits to be gained from increasing the percentage of STEM professionals from underrepresented groups. To this end, The Tapia Conference serves both functions, as it connects STEM students with STEM professionals, leaders, and academics who share the vision of a STEM workforce and community that is truly representative of the community in which we live.

  3. Evaluation of the Ross fast solution of Richards' equation in unfavourable conditions for standard finite element methods

    International Nuclear Information System (INIS)

    Crevoisier, D.; Voltz, M.; Chanzy, A.

    2009-01-01

    Ross [Ross PJ. Modeling soil water and solute transport - fast, simplified numerical solutions. Agron J 2003;95:1352-61] developed a fast, simplified method for solving Richards' equation. This non-iterative 1D approach, using Brooks and Corey [Brooks RH, Corey AT. Hydraulic properties of porous media. Hydrol. papers, Colorado St. Univ., Fort Collins: 1964] hydraulic functions, allows a significant reduction in computing time while maintaining the accuracy of the results. The first aim of this work is to confirm these results in a more extensive set of problems, including those that would lead to serious numerical difficulties for the standard numerical method. The second aim is to validate a generalisation of the Ross method to other mathematical representations of hydraulic functions. The Ross method is compared with the standard finite element model, Hydrus-1D [Simunek J, Sejna M, Van Genuchten MTh. The HYDRUS-1D and HYDRUS-2D codes for estimating unsaturated soil hydraulic and solutes transport parameters. Agron Abstr 357; 1999]. Computing time, accuracy of results and robustness of numerical schemes are monitored in 1D simulations involving different types of homogeneous soils, grids and hydrological conditions. The Ross method associated with modified Van Genuchten hydraulic functions [Vogel T, Cislerova M. On the reliability of unsaturated hydraulic conductivity calculated from the moisture retention curve. Transport Porous Media 1988:3:1-15] proves in every tested scenario to be more robust numerically, and the compromise of computing time/accuracy is seen to be particularly improved on coarse grids. Ross method run from 1.25 to 14 times faster than Hydrus-1D. (authors)

  4. ‘By Force of Participation and Conjunction in Him’: John Jewel and Richard Hooker on Union with Christ

    Directory of Open Access Journals (Sweden)

    Gazal André A.

    2014-06-01

    Full Text Available The author of a Christian Letter cited a passage from John Jewel’s A Reply to Harding’s Answer in which the first major apologist of the Elizabethan Settlement spoke of the role of faith and the sacraments in union with Christ. Andrew Willet, the likely author of this work, quoted it against Richard Hooker in order to show how the latter contravened the sacramental theology of the national Church as interpreted by Jewel as one of the foremost expositors of its doctrine. Jewel, however, in his Reply to Harding’s Answer, enumerates four means of the Christian’s union with Christ: the Incarnation, faith, baptism, and the Eucharist-a fact overlooked in A Christian Letter by its author in his endeavor to impeach Hooker’s orthodoxy. Proceeding from the observation that both Jewel and Hooker believed that the locus of Christian salvation is union with Christ, this essay compares the two divines’ respective views of this union by examining the manner in which they understand the role of each of these means forming and maintaining this union. On the basis of this comparison, the essay argues that A Christian Letter misrepresented Jewel’s position and that Hooker’s view of union with Christ was essentially the same as the late bishop of Salisbury’s, notwithstanding some differences in detail and emphases. The article concludes with the opinion that Hooker represents continuity of a particular soteriological emphasis in the Elizabethan Church that can possibly be traced back to Jewel as a representative of the Reformed tradition stressing this doctrine.

  5. Rezension: World Wide War: Angriff aus dem Internet/Cyber War: The Next Threat to National Security and What to Do About It von Richard A. Clarke und Robert K. Knake/by Richard A. Clarke and Robert K. Knake

    Directory of Open Access Journals (Sweden)

    Karl H. Stingeder

    2015-03-01

    Full Text Available Je breiter der Infrastruktur-Anschluss eines Landes an das World Wide Web, desto größer die Angriffsfläche im Fall eines Netzkriegs. Die Messung der virtuellen Kampfkraft erfolgt auf Basis von drei Faktoren: Offensivkraft, Defensivfähigkeit und die Abhängigkeit vom Internet. Die USA verfügen als "Supermacht" zwar über die größte virtuelle Offensivkraft, gleichzeitig steht die Nation Cyberangriffen sehr verwundbar gegenüber. Dagegen sind in Nordkorea kaum Systeme vom Internet abhängig. Obwohl die offensiven Netzkriegskapazitäten Nordkoreas verhältnismäßig gering sind, präsentiert sich die virtuelle Kampfkraft des nordkoreanischen Regimes in Bestform. Die Verwundbarkeit ziviler Systeme, insbesondere der Energieversorgung, muss in direkter Korrelation mit deren Anknüpfung an das Internet betrachtet werden. The more broadly connected a country’s infrastructure and energy distribution, the greater its vulnerability in the event of a cyber war. Measuring this virtual fighting power is based on three factors: offensive and defensive strength, as well as dependency on the Internet. As a superpower, the USA has the greatest virtual offensive strength available. At the same time, the nation is most susceptible to cyber attacks and therefore most vulnerable. By contrast, North Korea’s offensive cyber fighting power is relatively small, but its overall cyber war capabilities are cutting-edge. The vulnerability of civil systems, especially power supply, must be viewed in direct correlation to their connection to the Internet.

  6. Neodadjuvante und adjuvante Kurzzeit-Hormontherapie in Kombination mit konformaler HDR-Brachytherapie beim Prostatakarzinom

    Directory of Open Access Journals (Sweden)

    Martin T

    2004-01-01

    Full Text Available Zielsetzung: Auswertung der Behandlungsergebnisse der neoadjuvanten und adjuvanten Kurzzeit-Hormontherapie kombiniert mit konformaler HDR-Brachytherapie und externer Radiotherapie beim Prostatakarzinom. Patienten und Methoden: Von 01/97 bis 09/99 behandelten wir 102 Patienten mit Prostatakarzinomen im Stadium T1–3 N0 M0. Im Stadium T1–2 befanden sich 71, im Stadium T3 31 Patienten. Der mediane prätherapeutische PSA-Wert betrug 15,3 ng/ml. Nach ultraschallgesteuerter transrektaler Implantation von vier Afterloadingnadeln erfolgte die CT-gestützte 3D-Brachytherapie- Planung. Alle Patienten erhielten vier HDR-Implantate mit einer Referenzdosis von 5 Gy oder 7 Gy pro Implantat. Die Zeit zwischen jedem Implantat betrug jeweils 14 Tage. Nach der Brachytherapie folgte die externe Radiotherapie bis 39,6 Gy oder 45,0 Gy. Alle Patienten erhielten eine neoadjuvante und adjuvante Kurzzeit-Hormontherapie, die 2–19 Monate vor der Brachytherapie eingeleitet und 3 Monate nach Abschluß der externen Radiotherapie abgesetzt wurde (mediane Dauer: 9 Monate. Ergebnisse: Die mediane Nachbeobachtungszeit war 2,6 Jahre (range: 2,0–4,1 Jahre. Die biochemische Kontrollrate betrug 82 % nach 3 Jahren. Bei 14/102 Patienten registrierten wir ein biochemisches Rezidiv, bei 5/102 Patienten ein klinisches Rezidiv. Das Gesamtüberleben betrug 90 %, das krankheitsspezifische Überleben 98,0 % nach 3 Jahren. Ein Patient entwickelte eine prostato-urethro-rektale Fistel als späte Grad 4-Toxizität. Akute Grad-3 Toxizitäten traten bei 4 %, späte Grad-3 Toxizitäten bei 5 % der Patienten auf. Schlußfolgerung: Die neoadjuvante und adjuvante Kurzzeit-Hormontherapie kombiniert mit konformaler HDR-Brachytherapie und externer Radiotherapie erweist sich als sichere und wirksame Behandlungsmodalität beim Prostatakarzinom mit minimalen behandlungsbedingten Toxizitäten und einer vielversprechenden biochemischen Kontrollrate nach medianer Nachbeobachtungszeit von 2,6 Jahren.

  7. Furosemide urogram in patients with neobladder; Das Diureseurogramm bei Patienten mit Harnblasenersatz

    Energy Technology Data Exchange (ETDEWEB)

    Merkle, E.M. [Univ. Ulm (Germany). Abt. Radiologie; Aschoff, A.J. [Univ. Ulm (Germany). Abt. Radiologie; Bachor, R. [Univ. Ulm (Germany). Abt. fuer Urologie; Vogel, J. [Univ. Ulm (Germany). Abt. Radiologie; Merk, J. [Univ. Ulm (Germany). Abt. Radiologie; Brambs, H.J. [Univ. Ulm (Germany). Abt. Radiologie

    1996-11-01

    Purpose: To differentiate between urodynamically relevant obstruction and functionally unimportant dilation of the upper urinary tract in patients with neobladder using a modified furosemide urogram. Method: An excretory urogram with furosemide loading was carried out in 19 patients with neobladder and sonographically and urographically confirmed dilation of the upper urinary tract. Once strong contrasting of the renal pelves and calyces has been achieved, 20 mg of furosemide were applied and late radiographs were obtained at 15 min and 30 min, respectively. An obstruction was defined as increasing dilation of the renal pelves and calices during forced diuresis and lack of washout effect of the contrast medium. Results: In 32 cases, the renoureteral unit (RUU) was dilated on ultrasound. Of these, 25 RUU`s showed good emptyness of contrast medium upon stimulation of diuresis, six RUU`s returned a borderline findings, while one RUU was found to exhibit a decompensated anastomotic stenosis, which was dilated. Two further patients with bordeline findings were later treated surgically due to their pain symptoms. No patient required further preoperative diagnostic procedures. Conclusions: The modified furosemide urogram represents a cost-effective diagnostic orientation strategy in patients with neobladder and dilated renal pelves and calyses and is both well-tolerated by patients and meets with broad acceptance from the urologic staff. (orig.) [Deutsch] Ziel: Differenzierung zwischen urodynamisch relevanter Obstruktion und funktionell bedeutungsloser Dilatation des oberen Harntraktes bei Patienten mit Harnblasenersatz durch ein modifiziertes Diureseurogramm. Methodik: Bei 19 Patienten mit Harnableitung und sonographisch sowie urographisch nachgewiesener Erweiterung des oberen Harntraktes wurde ein Ausscheidungsurogramm mit Furosemidbelastung durchgefuehrt. Bei kraeftiger Kontrastierung des erweiterten Nierenbeckenkelchsystems (NBKS) wurden 20 mg Furosemid appliziert und

  8. Lt Richard Gueli

    African Journals Online (AJOL)

    Win98SE

    reality, conflicts in Africa (and other parts of the world), often fuelled by deep- ... Often, confusion exists between what is meant by human rights law and .... assist peoples in their right to self-determination; as a result of a state formally consenting ...... As regional 'superpower', it could be argued that South Africa should take a.

  9. Richard Phillips Feynman

    Indian Academy of Sciences (India)

    ARTICLE-IN-A-BOX. 797. RESONANCE │ September 2011. The war years interrupted the efforts of both Feynman and Schwinger to tackle the divergence problems in quantum electrodynamics, another of Dirac's pioneering creations from 1927. In 1965 the Physics Nobel Prize was shared by the two of them and Sin-Ichiro ...

  10. Richard Phillips Feynman

    Indian Academy of Sciences (India)

    While the two relativity theories were largely the creation of Albert Einstein, the quantum ... of what may lie in store for anyone who dares to follow the beat of a different drum. ... saw Feynman's exceptional talents and in a special lecture explained to him the beautiful principle ... The Character of Physical Law – 1965. c).

  11. [Richard C. M. Mole: The Baltic states from the Soviet Union to the European Union. Identity, discourse and power in the post-communist transition of Estonia, Latvia and Lithuania] / Karsten Brüggemann

    Index Scriptorium Estoniae

    Brüggemann, Karsten, 1965-

    2014-01-01

    Arvustus: Mole, Richard C. M. The Baltic States from the Soviet Union to the European Union : identity, discourse and power in the post-communist transition of Estonia, Latvia and Lithuania. London ; New York : Routledge, 2012, 2013

  12. MitProNet: A knowledgebase and analysis platform of proteome, interactome and diseases for mammalian mitochondria.

    Directory of Open Access Journals (Sweden)

    Jiabin Wang

    Full Text Available Mitochondrion plays a central role in diverse biological processes in most eukaryotes, and its dysfunctions are critically involved in a large number of diseases and the aging process. A systematic identification of mitochondrial proteomes and characterization of functional linkages among mitochondrial proteins are fundamental in understanding the mechanisms underlying biological functions and human diseases associated with mitochondria. Here we present a database MitProNet which provides a comprehensive knowledgebase for mitochondrial proteome, interactome and human diseases. First an inventory of mammalian mitochondrial proteins was compiled by widely collecting proteomic datasets, and the proteins were classified by machine learning to achieve a high-confidence list of mitochondrial proteins. The current version of MitProNet covers 1124 high-confidence proteins, and the remainders were further classified as middle- or low-confidence. An organelle-specific network of functional linkages among mitochondrial proteins was then generated by integrating genomic features encoded by a wide range of datasets including genomic context, gene expression profiles, protein-protein interactions, functional similarity and metabolic pathways. The functional-linkage network should be a valuable resource for the study of biological functions of mitochondrial proteins and human mitochondrial diseases. Furthermore, we utilized the network to predict candidate genes for mitochondrial diseases using prioritization algorithms. All proteins, functional linkages and disease candidate genes in MitProNet were annotated according to the information collected from their original sources including GO, GEO, OMIM, KEGG, MIPS, HPRD and so on. MitProNet features a user-friendly graphic visualization interface to present functional analysis of linkage networks. As an up-to-date database and analysis platform, MitProNet should be particularly helpful in comprehensive studies of

  13. Good planning for maximum efficiency. Part 1. Housing development of passive buildings with solar district heat supply; Sauber geplant is halb gewonnen. Teil 1. Passivhaussiedlung mit solarer Nahwaermeversorgung

    Energy Technology Data Exchange (ETDEWEB)

    Meissner, R. [Ritter Energie- und Umwelttechnik, Karlsbad (Germany)

    2003-06-01

    A new development of 12 single-family dwellings was constructed with complex technical facilities and many innovative elements by Gewerbepark Ritter and Messrs. Paradigma, a provider of thermal solar systems. [German] Der Gewerbepark Ritter und die auf thermische Solarindustrie spezialisierte Firma Paradigma haben bei der Errichtung einer Siedlung mit 12 Einfamilienhaeusern mit einem komplexen Haustechnikkonzept ein wegweisendes Projekt mit vielen innovativen Neuerungen erfolgreich in die Tat umgesetzt. (orig.)

  14. Binding of Substrates to the Central Pore of the Vps4 ATPase Is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs).

    Science.gov (United States)

    Han, Han; Monroe, Nicole; Votteler, Jörg; Shakya, Binita; Sundquist, Wesley I; Hill, Christopher P

    2015-05-22

    The endosomal sorting complexes required for transport (ESCRT) pathway drives reverse topology membrane fission events within multiple cellular pathways, including cytokinesis, multivesicular body biogenesis, repair of the plasma membrane, nuclear membrane vesicle formation, and HIV budding. The AAA ATPase Vps4 is recruited to membrane necks shortly before fission, where it catalyzes disassembly of the ESCRT-III lattice. The N-terminal Vps4 microtubule-interacting and trafficking (MIT) domains initially bind the C-terminal MIT-interacting motifs (MIMs) of ESCRT-III subunits, but it is unclear how the enzyme then remodels these substrates in response to ATP hydrolysis. Here, we report quantitative binding studies that demonstrate that residues from helix 5 of the Vps2p subunit of ESCRT-III bind to the central pore of an asymmetric Vps4p hexamer in a manner that is dependent upon the presence of flexible nucleotide analogs that can mimic multiple states in the ATP hydrolysis cycle. We also find that substrate engagement is autoinhibited by the Vps4p MIT domain and that this inhibition is relieved by binding of either Type 1 or Type 2 MIM elements, which bind the Vps4p MIT domain through different interfaces. These observations support the model that Vps4 substrates are initially recruited by an MIM-MIT interaction that activates the Vps4 central pore to engage substrates and generate force, thereby triggering ESCRT-III disassembly. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  15. Binding of Substrates to the Central Pore of the Vps4 ATPase Is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs)*

    Science.gov (United States)

    Han, Han; Monroe, Nicole; Votteler, Jörg; Shakya, Binita; Sundquist, Wesley I.; Hill, Christopher P.

    2015-01-01

    The endosomal sorting complexes required for transport (ESCRT) pathway drives reverse topology membrane fission events within multiple cellular pathways, including cytokinesis, multivesicular body biogenesis, repair of the plasma membrane, nuclear membrane vesicle formation, and HIV budding. The AAA ATPase Vps4 is recruited to membrane necks shortly before fission, where it catalyzes disassembly of the ESCRT-III lattice. The N-terminal Vps4 microtubule-interacting and trafficking (MIT) domains initially bind the C-terminal MIT-interacting motifs (MIMs) of ESCRT-III subunits, but it is unclear how the enzyme then remodels these substrates in response to ATP hydrolysis. Here, we report quantitative binding studies that demonstrate that residues from helix 5 of the Vps2p subunit of ESCRT-III bind to the central pore of an asymmetric Vps4p hexamer in a manner that is dependent upon the presence of flexible nucleotide analogs that can mimic multiple states in the ATP hydrolysis cycle. We also find that substrate engagement is autoinhibited by the Vps4p MIT domain and that this inhibition is relieved by binding of either Type 1 or Type 2 MIM elements, which bind the Vps4p MIT domain through different interfaces. These observations support the model that Vps4 substrates are initially recruited by an MIM-MIT interaction that activates the Vps4 central pore to engage substrates and generate force, thereby triggering ESCRT-III disassembly. PMID:25833946

  16. Vitex-agnus-castus-Extrakt (Ze 440 zur Symptombehandlung bei Frauen mit menstruellen Zyklusstörungen

    Directory of Open Access Journals (Sweden)

    Eltbogen R

    2015-01-01

    Full Text Available Ziel: Diese nichtinterventionelle Beobachtungsstudie (NIS wurde von Schweizer Gynäkologen und Allgemeinmedizinern im Rahmen der üblichen ärztlichen Grundversorgung durchgeführt. Das Ziel der NIS war es, die Wirksamkeit und Sicherheit von Vitex-agnus-castus-(VAC Extrakt (Ze 440: premens, Zeller Medical AG, Romanshorn, Schweiz bei Frauen, die unter menstruellen Zyklusstörungen wie Polymenorrhö, Oligomenorrhö oder Amenorrhö litten, zu untersuchen. Methode: Insgesamt 211 Patientinnen nahmen an dieser NIS teil. Symptome, die mit menstruellen Zyklusstörungen („menstrual cycle irregularities“ [MCIs] und der Menstruationsblutung in Verbindung stehen, wurden bei einer Erstuntersuchung („baseline visit“ [BV] und einer Kontrolluntersuchung („follow-up visit“ [FV] nach Behandlung mit VAC-Extrakt über einen Zeitraum von 3 aufeinanderfolgenden Menstruationszyklen beurteilt. Ergebnisse: Der Anteil der Patientinnen, bei denen eine Beschwerdefreiheit oder eine Besserung der MCIs (insgesamt und spezifischer Beschwerdebilder wie Polymenorrhö, Oligomenorrhö und Amenorrhö erzielt werden konnte, lag bei der FV bei 79–85 %. Bei Symptomen im Zusammenhang mit der Menstruationsblutung wie Dysmenorrhö, Zwischenblutungen, Hypermenorrhö, Menometrorrhagie, Ovulationsblutung, präoder postmenstrueller Blutung betrug der Anteil der Patientinnen, bei denen ein Rückgang oder eine Besserung festgestellt wurde, bei der FV zwischen 60 und 88 %. Von 53 Patientinnen, die bei der BV von einem unerfüllten Kinderwunsch berichteten, wurden 12 Frauen (23 % während der Behandlung mit VAC-Extrakt schwanger. Bei der FV waren 91 % der Ärzte und 92 % der Patientinnen mit den erzielten Behandlungsergebnissen „zufrieden“ oder „sehr zufrieden“ und 80 % der Patientinnen bestätigten, dass sie gerne mit der Behandlung mit VAC-Extrakt fortfahren wollen. Fazit: Diese Beobachtungsstudie im Bereich der ärztlichen Grundversorgung ergab, dass die Behandlung mit VAC

  17. Metacognitive Interpersonal Therapy in group (MIT-G) for young adults with personality disorders: A pilot randomized controlled trial.

    Science.gov (United States)

    Popolo, Raffaele; MacBeth, Angus; Canfora, Flaviano; Rebecchi, Daniela; Toselli, Cecilia; Salvatore, Giampaolo; Dimaggio, Giancarlo

    2018-04-06

    Young adults with personality disorders (PD) other than borderline are in urgent need of validated treatments to help them in managing important life transitions. Therapeutic interventions focused upon social and interpersonal difficulties may facilitate these individuals in maximizing opportunities for employment, forming stable romantic relationships, and belong to social groups. It is also important that they are offered evidence-based, first-line time-limited treatments in order to maximize effectiveness and reduce costs. We developed a 16-session programme of group-based Metacognitive Interpersonal Therapy (MIT-G) including psychoeducation on the main interpersonal motives, an experiential component enabling practice of awareness of mental states; and use of mentalistic knowledge for purposeful problem-solving. We report a feasibility, acceptability, and clinical significance randomized clinical trial. Participants meeting inclusion criteria were randomized to receive MIT-G (n = 10) or waiting list+TAU (n = 10). Dropout rate was low and session attendance high (92.19%). Participants in the MIT-G arm had symptomatic and functional improvements consistent with large effect sizes. In the MIT-G arm similarly large effects were noted for increased capacity to understand mental states and regulate social interactions using mentalistic knowledge. Results were sustained at follow-up. Our findings suggest potential for applying MIT-G in larger samples to further test its effectiveness in reducing PD-related symptoms and problematic social functioning. © 2018 The British Psychological Society.

  18. Eddy current testing with high penetration; WS-Pruefungen mit grosser Eindringtiefe

    Energy Technology Data Exchange (ETDEWEB)

    Becker, R.; Kroening, M. [Fraunhofer Inst. fuer Zerstoerungsfreie Pruefverfahren, Saarbruecken (Germany)

    1999-08-01

    The low-frequency eddy current testing method is used when penetration into very deep layers is required. The achievable penetration depth is determined among other parameters by the lowest testing frequency that can be realised together with the eddy current sensor. When using inductive sensors, the measuring effect declines proportional to the lowering frequency (induction effect). Further reduction of testing frequency requires other types of sensors, as e.g. the GMR (Giant Magnetic Resistance), which achieves a constant measuring sensitivity down to the steady field. The multi-frequency eddy current testing method MFEC 3 of IZFP described here can be operated using three different scanning frequencies at a time. Two variants of eddy current probes are used in this case. Both have an inductive winding at their emitters, of the type of a measuring probe. The receiver end is either also an inductive winding, or a magnetic field-responsive resistance (GMR). (orig./CB) [Deutsch] Das Niederfrequenz(NF)-Wirbelstrom(WS)-Verfahren wird eingesetzt, um eine grosse Eindringtiefe zu erzielen. Die erreichbare Tiefenreichweite wird u.a. durch die niedrigste Prueffrequenz bestimmt, die zusammen mit dem Wirbelstrom-Sensor realisiert werden kann. Bei Einsatz von induktiven Sensoren geht mit abnehmender Prueffrequenz der Messeffekt proportional zurueck (Induktionswirkung). Eine weitere Absenkung der Prueffrequenzen macht den Einsatz von andersartigen Sensoren notwendig, z.B. den GMR (Giant Magnetic Resistance), der eine gleichmaessige Messempfindlichkeit bis zum Gleichfeld besitzt. Das eingesetzte Mehrfrequenz-Wirbelstrom-Pruefverfahren MFEC 3 des IZFP arbeitet mit drei gleichzeitig eingespeisten Prueffrequenzen. Dabei werden zwei Varianten von WS-Sensoren eingesetzt. Beide besitzen auf der Senderseite eine induktive Wicklung in der Art einer Tastsonde. Die Empfaengerseite ist entweder ebenfalls eine induktive Wicklung oder ein magnetfeldempfindlicher Widerstand (GMR). (orig./DGE)

  19. Regional climate projection of the Maritime Continent using the MIT Regional Climate Model

    Science.gov (United States)

    IM, E. S.; Eltahir, E. A. B.

    2014-12-01

    Given that warming of the climate system is unequivocal (IPCC AR5), accurate assessment of future climate is essential to understand the impact of climate change due to global warming. Modelling the climate change of the Maritime Continent is particularly challenge, showing a high degree of uncertainty. Compared to other regions, model agreement of future projections in response to anthropogenic emission forcings is much less. Furthermore, the spatial and temporal behaviors of climate projections seem to vary significantly due to a complex geographical condition and a wide range of scale interactions. For the fine-scale climate information (27 km) suitable for representing the complexity of climate change over the Maritime Continent, dynamical downscaling is performed using the MIT regional climate model (MRCM) during two thirty-year period for reference (1970-1999) and future (2070-2099) climate. Initial and boundary conditions are provided by Community Earth System Model (CESM) simulations under the emission scenarios projected by MIT Integrated Global System Model (IGSM). Changes in mean climate as well as the frequency and intensity of extreme climate events are investigated at various temporal and spatial scales. Our analysis is primarily centered on the different behavior of changes in convective and large-scale precipitation over land vs. ocean during dry vs. wet season. In addition, we attempt to find the added value to downscaled results over the Maritime Continent through the comparison between MRCM and CESM projection. Acknowledgements.This research was supported by the National Research Foundation Singapore through the Singapore MIT Alliance for Research and Technology's Center for Environmental Sensing and Modeling interdisciplinary research program.

  20. MIT Project Apophis: Surface Evaulation & Tomography (SET) Mission Study for the April 2029 Earth Encounter

    Science.gov (United States)

    Binzel, R. P.; Earle, A. M.; Vanatta, M.; Miller, D. W.

    2017-12-01

    Nature is providing a once-per-thousand year opportunity to study the geophysical outcome induced on an unprecedentedly large (350 meter) asteroid making an extremely close passage by the Earth (inside the distance of geosynchronous satellites) on Friday April 13, 2029. The aircraft carrier-sized (estimated 20 million metric ton) asteroid is named Apophis. While many previous spacecraft missions have studied asteroids, none has ever had the opportunity to study "live" the outcome of planetary tidal forces on their shapes, spin states, surface geology, and internal structure. Beyond the science interest directly observing this planetary process, the Apophis encounter provides an invaluable opportunity to gain knowledge for any eventuality of a known asteroid found to be on a certain impact trajectory. MIT's Project Apophis [1] is our response to nature's generous opportunity by developing a detailed mission concept for sending a spacecraft to orbit Apophis with the objectives of surveying its surface and interior structure before, during, and after its 2029 near-Earth encounter. The Surface Evaluation & Tomography (SET) mission concept we present is designed toward accomplishing three key science objectives: (1) bulk physical characterization, (2) internal structure, and (3) long-term orbit tracking. For its first mission objective, SET will study Apophis' bulk properties, including: shape, size, mass, volume, bulk density, surface geology, and composition, rotation rate, and spin state. The second mission objective is to characterize Apophis' internal structure before and after the encounter to determine its strength and cohesion - including tidally induced changes. Finally, the third objective studies the process of thermal re-radiation and consequential Yarkovsky drift, whose results will improve orbit predictions for Apophis as well as other potentially hazardous asteroids. [1] https://eapsweb.mit.edu/mit-project-apophis

  1. [Cardiodoron® bei Patienten mit Schlafstörungen - Ergebnisse einer prospektiven Beobachtungsstudie].

    Science.gov (United States)

    Rother, Claudia; Schnelle, Martin

    Hintergrund: Schlafstörungen gehören zu den häufigsten gesundheitlichen Problemen der heutigen Zeit. Stress und die dadurch bedingte innere Anspannung sowie eine unrhythmische Lebensführung z.B. durch Schichtarbeit sind bekannte auslösende Faktoren. Weniger bekannt ist, dass auch funktionelle Herz-Kreislauf-Beschwerden zu Störungen des Schlafs führen können und dass deren Behandlung zu einer Verbesserung der Schlafqualität beiträgt. Ganzheitlich betrachtet geht es daher um die Wiederherstellung einer gesunden Rhythmik, insbesondere des Herz-/Atem- sowie des Schlaf-Wach-Rhythmus, die Cardiodoron®, eine Heilpflanzenkomposition aus Primula veris, Hyoscyamus niger und Onopordum acanthium, unterstützt. Patienten und Methoden: Mittels einer prospektiven, multizentrischen Beobachtungsstudie sollte ermittelt werden, wie sich funktionelle Herz-Kreislauf-Beschwerden und/oder Schlafstörungen unter der Behandlung mit Cardiodoron® (Dilution) über 3-6 Monate entwickeln. Im Zeitraum von September 2009 bis März 2012 dokumentierten 92 Ärzte 501 Patienten, von denen 380 über Schlafstörungen klagten und deren Daten in dieser Publikation näher betrachtet werden. Nach einer Aufnahmeuntersuchung erfolgte nach 90 Tagen eine Abschlussuntersuchung und bei Fortführung der Therapie nach nochmals 90 Tagen eine Follow-up-Untersuchung. Neben 30 ärztlicherseits bewerteten Symptomen beurteilten die Patienten ihr Befinden mittels Pittsburgh Sleep Quality Index (PSQI) nach Buysse und der Beschwerden-Liste nach von Zerssen (B-L und B-L'). Ergebnisse: Unter der Cardiodoron®-Therapie gingen bei guter Verträglichkeit sowohl die Ausprägung der Schlafstörungen (um 65% von 2,0 auf 0,7 Punkte) als auch die erfassten 30 Symptome (um 59% von 24,3 auf 9,9 Punkte) deutlich zurück (p mit Schlafstörungen (mit oder ohne funktionelle Herz-Kreislauf-Beschwerden) kann die Ausprägung der Beschwerden mit Cardiodoron® deutlich gesenkt werden. Cardiodoron® ist gut verträglich. © 2016 S

  2. Condensation energy of the Nambu-Jona-Lasinio vacuum and the MIT bag constant

    International Nuclear Information System (INIS)

    Li, S.; Bhalerao, R.S.; Bhaduri, R.K.

    1991-01-01

    In this paper the energy densities of the vacuum in the Wigner and the Goldstone modes of the Nambu- Jona-Lasinio Hamiltonian are calculated. The difference of these two quantities is analogous to the condensation energy of a BCS superconductor, and is used here to estimate the temperature dependence of the MIT bag constant. The formalism of da Providencia et al is generalized to finite temperatures, yielding the same gap equation as the finite- temperature field theory. The thermodynamics of the vacuum in the two phases is studied

  3. Tank für Überschusshefe versagt – mit katastrophalen Folgen

    DEFF Research Database (Denmark)

    Hedlund, Frank Huess; Selig, Robert Simon

    2017-01-01

    Ein großer Tank für Überschusshefe flog in die Luft und nur noch die Bodenplatte und der Tankinhalt blieben zurück. Obwohl der Tank nicht für Überdruck ausgelegt war, wurde er auf ,"sehr geringem Überdruck" gehalten, um störende Schaumentwicklung zu verhindern. Der Brauerei waren die Gefahren dur...... Druckluft nicht bekannt. Der in diesem Artikel beschriebene Unfall soll aufzeigen, dass Vorsicht geboten ist, wenn ein ursprünglich für atmosphärischen Druck ausgelegter Tank auf Betrieb mit leichtem Überdruck abgeändert wird...

  4. Pembelajaran Embedded System Berbasis Arduino Mega 2560 dan MIT App Inventor

    OpenAIRE

    Tukadi, Tukadi

    2017-01-01

    This paper describes the learning process of the Embedded System course with a practical approach based on Arduino Mega 2560 and Android using MIT App inventor software. Learning materials include digital I / O and analog I / O access via android mobile phone. The method used in its implementation premises to provide tasks in the form of projects. The next step is to find the theories that can support in completing the project task. The project task is to control or read electronic devices co...

  5. Risikoabsicherung von Produkten/Prozessen mit der Fehlermöglichkeits- und Einflussanalyse (FMEA)

    OpenAIRE

    Schloske, Alexander

    2010-01-01

    Die FMEA stellt heutzutage eines der wichtigsten Werkzeuge des präventiven Risikomanagements dar. Die universell anwendbare Vorgehensweise des VDA hat sich dabei in der Industrie etabliert. Der Beitrag beschreibt aus der Sicht von 25 Jahren FMEA-Erfahrung, wie die FMEA zielführend erstellt wird und mit welchen Tipps und Tricks eine effiziente und effektive FMEA-Erstellung ermöglicht wird. Einen besonderen Schwerpunkt dabei bilden die präzise Bezeichnung von Funktion und Fehlfunktion, sowie di...

  6. New combined plant with integrated solar thermal energy; Neue Kombi-Anlage mit integrierter Solarwaerme

    Energy Technology Data Exchange (ETDEWEB)

    Leithner, R.; Dobrowolski, R.; Gresch, H. [Technische Univ. Braunschweig (Germany). Inst. fuer Waerme- und Brennstofftechnik

    1998-06-01

    In California there are already 350 MW{sub e} worth of solar thermal energy plants in operation on a more or less commercial basis. In these installations thermal oil in parabolic gutters is heated from 300 C to 400 C. The thermal oil passes its thermal energy on to a water vapour circuit via a heat exchanger. The water vapour circuit can also be heated with natural gas, for instance at night when solar energy is not available. However, as yet no existing plant fulfils all three of the following requirements: its construction should entail the lowest possible investment costs and it should be able to run without solar energy and without an expensive storage system; it should have the greatest possible efficiency, especially at times when solar energy is not available (e.g. at night); at the same time, the solar thermal energy should be harvested at the lowest possible temperature so as to make expensive concentrating equipment superfluous. These seemingly contradictory demands are now met by a new concept involving a combined gas and steam plant whose operation is based on the injection of water into the compressed air rather than on a high excess of air. This water is evaporated by solar thermal energy at temperatures below 170 C according to its partial pressure. [Deutsch] Es gibt bereits ueber 350 MWe solarthermische Anlagen in Kalifornien, die mehr oder weniger kommerziell betrieben werden. Bei diesen Anlagen wird Thermaloel von 300 C auf 400 C in Parabolrinnen erhitzt. In einem Waermetauscher gibt das Thermaloel die Waerme an einen Wasserdampfkreislauf ab, der auch mit Erdgas beheizt werden kann, wenn wie z.B. nachts keine Solarwaerme verfuegbar ist. In einem weiteren Schritt wurde vorgeschlagen, das Wasser direkt zu verdampfen. Keine dieser Anlagen genuegt jedoch gleichzeitig den folgenden drei Anforderungen: Die Anlage sollte mit moeglichst niedrigen Investitionskosten gebaut und auch ohne Solarwaerme bzw. ohne aufwendigen Speicher betrieben werden koennen

  7. Esclavos perfectos: historia breve de la ciberarquitectura en MIT (1959-1967

    Directory of Open Access Journals (Sweden)

    Daniel Cardoso Llach

    2012-07-01

    Full Text Available This paper addresses unexplored aspects of the relationship between military research at MIT, and the constitution, during the cold war years, of a techno-scientific discourse of architecture. Exploring primary sources from the "Computer-Aided Design Project" (1959-1967, this paper explains the emergence of a cybernetic understanding of design, and its transit into architectural culture. The article presents Nicholas Negroponte's use of the CAD project's technical and theoretical idioms to re-imagine architectural practice through a technocratic (and populist lens, and discusses aspects of its influence in contemporary techno-scientific design discourse.

  8. Von Donuts und Zucker: Mit Neutronen biologische Makromoleküle erforschen

    Science.gov (United States)

    May, Roland P.

    2003-05-01

    Für die Erforschung von Biomolekülen bieten Neutronen einzigartige Eigenschaften. Vor allem ihre unterschiedliche Wechselwirkung mit dem natürlichen Wasserstoff und seinem schweren Isotop Deuterium ermöglicht tiefe Einblicke in Struktur, Funktion und Dynamik von Proteinen, Nukleinsäuren und Biomembranen. Bei vielen Fragestellungen zur Strukturaufklärung gibt es kaum oder keine Alternative zum Neutron. Das Institut Laue-Langevin trägt Bahnbrechendes zum Erfolg der Neutronen-Methoden in der Biologie bei.

  9. Magnetic resonance imaging in the evaluation of pneumonia; Nachweis von pneumonischen Infiltraten mit der MRT

    Energy Technology Data Exchange (ETDEWEB)

    Eibel, R.; Herzog, P.; Dietrich, O.; Reiser, M.; Schoenberg, S.O. [Ludwig-Maximilians-Universitaet Muenchen (Germany). Institut fuer Klinische Radiologie; Rieger, C.; Ostermann, H. [Ludwig-Maximilians-Universitaet Muenchen (Germany). Abteilung fuer Haematologie/Onkologie, Klinikum Grosshadern

    2006-04-15

    Rundherde mit einem Durchmesser deutlich unterhalb der Schichtdicke nicht mehr zuverlaessig erfasst werden koennen. Auch Verkalkungen sind nicht mit der gleichen Sicherheit wie im CT zu identifizieren. Gleiches gilt fuer den Nachweis von Luftsicheln und -einschluessen in Laesionen. Mit Hilfe der parallelen Bildgebung koennen beide Lungenfluegel in 1-2 Atemstillstaenden mit einer Ortsaufloesung von 6 mm in der z-Achse und Submillimeteraufloesung in der x- und y-Ebene untersucht werden. Raumzeiten <10 min lassen sich so realisieren. Insbesondere fuer die Verlaufsbeurteilung von pneumonischen Infiltraten bei immunsupprimierten Patienten kann die MRT geeignet sein und zu einer geringeren Dosisexposition der Patienten beitragen. (orig.)

  10. MIT extraction method for measuring average subchannel axial velocities in reactor assemblies

    International Nuclear Information System (INIS)

    Hawley, J.T.; Chiu, C.; Todreas, N.E.

    1980-08-01

    The MIT extraction method for obtaining flow split data for individual subchannels is described in detail. An analysis of the method is presented which shows that isokinetic values of the subchannel flow rates are obtained directly even though the method is non-isokinetic. Time saving methods are discussed for obtaining the average value of the interior region flow split parameter. An analysis of the method at low bundle flow rates indicates that there is no inherent low flow rate limitation on the method and suggests a way to obtain laminar flow split data

  11. Recent results from the MIT in-core experiments on coolant chemistry

    International Nuclear Information System (INIS)

    Harling, O.K.; Kohse, G.E.; Cabello, E.C.; Bernard, J.A.

    1993-01-01

    This paper reports results from an ongoing series of in-core experiments that have been conducted at the 5-MW(thermal) MIT Research Reactor (MITR-II) for optimizing coolant chemistries in light water reactors. Four experiments are in progress, including a pressurized coolant chemistry loop (PCCL), a boiling coolant chemistry loop (BCCL), a facility for the study of irradiation-assisted stress-corrosion cracking, and one for the evaluation of in situ sensors for the monitoring of crack propagation in metal (SENSOR). The first two have now been fully operational for several years. The latter two are scheduled to begin regular operation later this year

  12. Summary and recommendations for the NASA/MIT workshop on short haul air transport

    Science.gov (United States)

    Simpson, R. W.

    1971-01-01

    The material is summarized that was covered by the MIT/NASA Waterville Valley workshop which dealt with the institutional, socio-economic, operational and technological problems associated with introducing new forms of short haul domestic air transportation. It was found that future air systems hold great potential in satisfying society's needs for a low noise, low landspace, high access, high speed, large network system for public travel over distances between 5 and 500 miles. It is concluded that quiet air systems are necessary for obtaining community approval, and is recommended that extremely high priority be assigned to the development of quiet aircraft for future short haul air systems.

  13. Aufgabenorientierung mit proaktiver Formfokussierung als didaktisches Konzept für den Deutschunterricht im Tourismus

    Directory of Open Access Journals (Sweden)

    Gloria Bosch Roig

    2012-04-01

    Full Text Available Der aufgabenoriente Unterricht Deutsch für den Tourismus stellt eine realitätsnähere Variante des kommunikativen Deutschunterrichts dar, die es ermöglicht, sinnvolle Inhalte mit der effizienten Bewältigung konkreter Interaktionssituationen des Berufslebens zu kombinieren. Dabei werden die formellen Aspekte der Sprache weder aus dem Unterricht ausgeklammert noch als reine Form-Funktionsbeziehungen eingeführt. Grammatik wird vielmehr als eine metasprachliche Aufgabe verstanden, die es kooperativ und interaktiv zu entschlüsseln und zu lösen gilt.

  14. Intraläsionale Therapie niedrig maligner primär kutaner B-Zell-Lymphome mit Anti-CD20-Antikörper: Nebenwirkungen korrelieren mit gutem klinischen Ansprechen.

    Science.gov (United States)

    Eberle, Franziska C; Holstein, Julia; Scheu, Alexander; Fend, Falko; Yazdi, Amir S

    2017-03-01

    Die intraläsionale Gabe von Anti-CD20-Antikörpern (Rituximab) wurde als effektive Therapieoption für Patienten mit niedrig malignen primär kutanen B-Zell-Lymphomen beschrieben. Bis heute wurden allerdings keine Parameter identifiziert, welche reproduzierbar ein gutes klinisches Ansprechen dieser Therapie vorhersagen. Ziel dieser Studie ist, sowohl das klinische Ansprechen und die unerwünschten Nebenwirkungen als auch die Patientenwahrnehmung hinsichtlich intraläsionaler Injektionen von anti-CD20-Antikörpern zur Behandlung indolenter primär kutaner B-Zell-Lymphome im Vergleich mit anderen Therapien zu evaluieren. Elf Patienten mit einem primär kutanen B-Zell-Lymphom, namentlich primär kutanes Keimzentrumslymphom (n = 9) und primär kutanes Marginalzonenlymphom (n = 2), welche mittels intraläsionalem Anti-CD20-Antikörper behandelt wurden, wurden retrospektiv evaluiert hinsichtlich der Ansprechrate und unerwünschter Nebenwirkungen sowie in Bezug auf deren Selbsteinschätzung dieser und anderer Therapien des primär kutanen B-Zell-Lymphoms. Patienten, deren primär kutanes B-Zell-Lymphom mittels intraläsionaler Gabe von Anti-CD20-Antikörper behandelt wurde, zeigten ein komplettes oder partielles Ansprechen in 45 % beziehungsweise 27 % aller Patienten. Speziell Patienten mit grippeähnlichen Symptomen nach erfolgter Injektion zeigten ein gutes Ansprechen. Die Mehrheit der Patienten empfand die Therapie mit Rituximab als die beste Therapie im Vergleich zu anderen Therapien wie beispielsweise chirurgische Exzision oder Radiotherapie. Intraläsionales Rituximab ist eine effektive Therapie mit hoher Patientenzufriedenheit. Starke therapiebedingte Nebenwirkungen wie Fieber, Schüttelfrost und Kopfschmerzen nach Gabe von Rituximab könnten als Indikator für gute Wirksamkeit dienen. © 2017 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  15. J.M. Gratale on Tore T. Petersen’s Richard Nixon, Great Britain and the Anglo-American Alignment in the Persian Gulf and Arabian Peninsula

    Directory of Open Access Journals (Sweden)

    2009-09-01

    Full Text Available Tore T. Petersen. Richard Nixon, Great Britain and the Anglo-American Alignment in the Persian Gulf and Arabian Peninsula: Making Allies out of Clients. Sussex Academic Press, 2009.  172pp.  978-1-84519-277-8.Since the events of 9-11 there has been a sizeable quantity of books published on American foreign policy in broad terms, as well as more focused studies on contemporary developments in southwest Asia, more commonly referred to as the Middle East. Many of these volumes are highly politic...

  16. Espíritos cheios de bichos: A fauna nas viagens de Louis Agassiz e Richard Francis Burton pelo Brasil oitocentista

    Directory of Open Access Journals (Sweden)

    Janaina Zito Losada

    2015-04-01

    Full Text Available O Brasil do século XIX foi alvo de inúmeras viagens realizadas por cientistas estrangeiros. O objetivo deste artigo é analisar as impressões sobre a fauna brasileira presentes nos relatos das viagens realizadas pelo naturalista suíço Louis Agassiz, em 1865, e pelo explorador inglês Richard Francis Burton, em 1868. Destes relatos privilegiam-se as descrições do meio natural de diferentes regiões brasileiras e das particularidades da fauna silvestre por eles encontrada.

  17. Três décadas de genes egoístas: Discutindo algumas premissas do best seller de Richard Dawkins

    OpenAIRE

    Vieira, Eduardo Paiva de Pontes; Chaves, Silvia Nogueira

    2011-01-01

    O presente trabalho resgata algumas idéias do biólogo evolucionista Richard Dawkins, apresentadas pela primeira vez em seu best-seller O Gene Egoísta (The Selfish Gene), de 1976. O caráter polêmico de algumas concepções ultradarwinistas e sociobiológicas da obra é campo fértil para o embate de idéias, revelando um universo rico para discussões em diversas frentes, especialmente aquelas que podem se desenvolver na formação crítica de alguns profissionais vinculados á ciências biológicas, socio...

  18. Escatologia e história em Richard Shaull: a narrativa mítico-teológica entre a memória e o futuro

    Directory of Open Access Journals (Sweden)

    Arnaldo Érico Huff Júnior

    2013-01-01

    Full Text Available Resumo. O texto pretende pensar a produção da teologia da revolução de Richard Shaull no encontro entre escatologia e história. A partir de um breve relato dos anos de Shaull no Brasil, passa-se à análise das principais ideias teológicas que conduziram Shaull à formulação de uma assim chamada teologia da revolução. Finalmente, propõe-se uma chave interpretativa para a história da teologia, a partir de um diálogo com Reinhart Koselleck e Mircea Eliade.

  19. Thinking through war: the social thought of Richard T. Ely, John R. Commons, and Edward A. Ross during the First World War.

    Science.gov (United States)

    Herzberg, D L

    2001-01-01

    This paper examines the social thought of University of Wisconsin professors Richard T. Ely, John R. Commons, and Edward A. Ross during World War I. Like many of their fellow scholars, these three were actively involved in the pro-war effort. Although their support for the war was strongly conditioned by personal and occupational considerations, the impact of their wartime service was not restricted to those realms. Their social thought, which they impressed into service explaining and justifying the war, was itself altered in subtle and sometimes surprising ways by the forceful positions they took on the political, economic, and racial significance of the conflict. Copyright 2001 John Wiley & Sons, Inc.

  20. Die Dramatikerin Theresia Walser spricht mit Maria Aparecida Barbosa über das Theaterstück »King Kongs Töchter«. Mit einer Einführung von Karina Schuller

    Directory of Open Access Journals (Sweden)

    Theresia Walser

    2012-11-01

    Full Text Available In ihrem Interview spricht die Literaturwissenschaftlerin Maria Aparecida Barbosa mit der Dramatikerin Theresia Walser. Am Beispiel des Theaterstücks King Kongs Töchter (1998, das sich auf groteske Art und Weise mit dem Alltag in einem Altenheim befasst, werden dabei verschiedene Themen angesprochen: Es geht um die Selbstreflexivität des Theaters, um Walsers Verständnis von poetischer Sprache und Realismus sowie um den kreativen Schreibprozess im Allgemeinen. Ergänzt wird das Interview durch eine Einführung von Karina Schuller.

  1. MRI for therapy planning in patients with atrial septum defects; MRT zur Therapieplanung bei Patienten mit Vorhofseptumdefekt

    Energy Technology Data Exchange (ETDEWEB)

    Huber, A.; Rummeny, E. [Klinikum rechts der Isar, Technische Universitaet Muenchen, Institut fuer Radiologie, Muenchen (Germany); Prompona, M.; Reiser, M.; Theisen, D. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Institut fuer Klinische Radiologie, Muenchen (Germany); Kozlik-Feldmann, R. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Klinik und Poliklinik fuer Kinderkardiologie, Muenchen (Germany); Muehling, O. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Medizinische Klinik I, Muenchen (Germany)

    2011-01-15

    The aim of this study was to determine the value of a combined magnetic resonance imaging (MRI) protocol including steady-state free precession (SSFP) imaging, phase-contrast measurements and contrast-enhanced MR angiography (CE-MRA) for presurgical or preinterventional diagnostic imaging in patients with suspected atrial septum defects. Out of 65 MRI studies of patients with suspected atrial septum defects, 56 patients were included in the study. The atrial septum defects were identified on cine images. Velocity encoded flow measurements were used to determine shunt volumes, which were compared with invasive oxymetry in 24 patients. Contrast-enhanced MRI was used to assess the thoracic vessels in order to detect vascular anomalies. The findings were compared with the intraoperative results. A total of 24 patients with high shunt volumes were treated either surgically (16 patients) or interventionally (8 patients) and 32 patients with low shunt volumes did not require surgical or interventional treatment. The vascular anomaly, which in all cases was anomalous pulmonary venous return, was confirmed by the intraoperative findings. The type and location of atrial septal defects which required treatment, were confirmed intraoperatively or during the intervention. The results of shunt quantification by MRI showed a good correlation with the results of invasive oximetry (r=0.91, p <0.0001). A combined MRI protocol including cine SSFP images, velocity-encoded flow measurements and CE-MRA is an accurate method for preoperative and preinterventional evaluation of atrial septum defects. (orig.) [German] Ziel war es, die Wertigkeit eines kombinierten MRT-Protokolls aus Funktionsuntersuchung, Flussmessung und MR-Angiographie zur praeoperativen oder -interventionellen Abklaerung bei Patienten mit Vorhofseptumdefekt zu evaluieren. Ingesamt wurden 56 Patienten mit Vorhofseptumdefekt aus einem Kollektiv von 65 Patienten mit Verdacht auf Vorhofseptumdefekt, die im MRT untersucht

  2. UBER DIE SCHREIBUNG UND RECHTSCHREIBUNG MIT BESONDERER RÜCKSICHT AUF DIE RECHTSCHREIBUNGSLÖSUNGEN IN "FLUMINENSIA" VON FRAN KURELAC

    Directory of Open Access Journals (Sweden)

    Lada Badurina

    1990-01-01

    Full Text Available Im Artikel sind zunächst Grundsetzen der Schreibung und der Rechtschreibung dargestellt, demnach die Schreibung und die Rechtschreibung in "Fluminensia" von Fran Kurelac. Die von Kurelac vorgeschlagenen Lösungen sind mit den Lösungen seiner unmittelbaren Vorgänger und Zeitgenossen vergleicht, sowie mit der heutigen Rechtschreibungspraxis. Für die von Kurelac vorgeschlagne Schreibung ist festgestellt, daß es sich um ein beständiges System handelt, das von der Tradition ausgeht und das sich nur in eingen Lösungen von heutigen unterscheidet. In der Rechtschreibung überwiegt der morphologische Grundsatz, was leicht in Verbindung mit den Grundgedanken der Philologischen Schule in Rijeka zu steilen ist.

  3. O neopragmatismo de Richard Rorty e a reflexão política contemporânea

    Directory of Open Access Journals (Sweden)

    Sérgio Eduardo Ferraz

    2014-03-01

    Full Text Available Este artigo examina o pensamento filosófico de Richard Rorty e, em particular, sua dimensão política, delineando seu tratamento original e crítico de temas centrais à teoria política contemporânea. O objetivo do texto é triplo: chamar a atenção para a fertilidade das ideias de um autor ainda pouco lido no Brasil (i, assinalar as notáveis consequências corrosivas da abordagem rortyana para pressupostos e pretensões fundantes de importantes vertentes da teoria política (ii, e, numa ótica mais positiva, apontar o potencial inspirador dos escritos desse autor para a reflexão sobre novos modos de justificação da democracia (iii. Salientam-se também, nesse último caso, os limites impostos a esse tipo de empreitada político-intelectual. A abordagem empregada consiste em demarcar os contornos gerais do projeto filosófico do autor, seguindo-se uma apresentação dos tópicos mais propriamente políticos da obra de Rorty. Mais especificamente, o artigo explora a proposta rortyana de substituição da noção de verdade pela de justificação, assinalando-se suas consequências para pretensões de verdade, objetividade e universalismo, presentes em diversas linhas da teoria política. Nesse veio, o artigo discute as eventuais implicações relativistas das teses rortyanas, chegando-se, por essa rota, às ideias de contingência, imaginação e persuasão, núcleos conceituais vitais à reflexão em tela. Um breve contraste com posições de autores como Habermas e Rawls, caros ao próprio Rorty, é esboçado no propósito de tornar mais clara a especificidade da abordagem rortyana da política. Transitando, do modo assinalado, por esses tópicos, o texto resulta em um panorama sintético da perspectiva rortyana acerca do que vem a ser, contemporaneamente, uma "política democrática", liberta de "universalismos" e "objetividades", na qual ganham estatuto decisivo questões de justificação, tolerância e coexist

  4. Umgang mit Antithrombotika bei Operationen an der Haut vor und nach Publikation der entsprechenden S3-Leitlinie.

    Science.gov (United States)

    Gaskins, Matthew; Dittmann, Martin; Eisert, Lisa; Werner, Ricardo Niklas; Dressler, Corinna; Löser, Christoph; Nast, Alexander

    2018-03-01

    Laut einer Befragung im Jahre 2012 war der Umgang mit Antithrombotika bei dermatochirurgischen Eingriffen in Deutschland sehr heterogen. 2014 wurde erstmals eine evidenzbasierte Leitlinie zu diesem Thema veröffentlicht. Es wurde eine anonyme Befragung derselben Stichprobe zum Umgang mit Antithrombotika sowie zu Kenntnissen der Leitlinie durchgeführt. Die Ergebnisse wurden als relative Häufigkeiten berichtet und denen aus 2012 gegenübergestellt. 208 Antwortbögen wurden ausgewertet (Rücklaufquote: 36,6 %). Die große Mehrheit der Dermatologen erklärte, kleinere Eingriffe unter Fortführung der Therapie mit Phenprocoumon, niedrig dosierter Acetylsalicylsäure (≤ 100 mg) und Clopidogrel sowie mit direkten oralen Antikoagulanzien durchzuführen. Bei größeren Eingriffen war der Umgang hingegen weiterhin heterogen, insbesondere unter niedergelassenen Dermatologen. Der Anteil der Dermatologen, die Phenprocoumon, Acetylsalicylsäure und Clopidogrel leitlinienkonform verwendeten, hat sich insgesamt vergrößert. Führten 2012 beispielsweise 53,8 % der Klinikärzte bzw. 36,3 % der niedergelassenen Dermatologen eine große Exzision unter Fortführung der Therapie mit niedrig dosierter Acetylsalicylsäure durch, taten dies 2017 90,2 % bzw. 57,8 % (Phenprocoumon: 33,8 % bzw. 11,9 % auf 63,9 % bzw. 29,9 %; Clopidogrel: 36,9 % bzw. 23,2 % auf 63,9 % bzw. 30,6 %). Unter den Klinikärzten war ein hoher Anteil mit der Leitlinie vertraut und fand diese hilfreich. Eine Zunahme des leitlinienkonformen Verhaltens war bei allen Eingriffen zu verzeichnen. Bei größeren Eingriffen zeigte sich trotz deutlicher Verbesserung die Notwendigkeit verstärkter Anstrengungen zur Leitlinienumsetzung bzw. zur Identifizierung von Implementierungsbarrieren. © 2018 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  5. Computerunterstützte Sacherschließung mit dem Digitalen Assistenten (DA-2

    Directory of Open Access Journals (Sweden)

    Imma Hinrichs

    2016-12-01

    Full Text Available Wir beschreiben den Digitalen Assistenten DA-2, den wir zur Unterstützung der Sacherschliessung im IBS-Verbund implementiert haben. Diese webbasierte Anwendung ist eine vollständige Neuimplementierung, welche die Erkenntnisse des Vorgängersystems bei der Zentralbibliothek Zürich berücksichtigt. Wir stellen Überlegungen zur Zukunft der Sacherschliessung an und geben eine Übersicht über Projekte mit ähnlichen Zielsetzungen, die Sacherschließung mit Computerunterstützung effizienter und besser zu gestalten.   We describe the digital assistant DA-2 which we have implemented to support the subject indexing process in the IBS-Verbund. This web-based service is a new implementation from scratch based on the lessons learned with its predecessor used by the Zentralbibliothek Zürich. We also discuss the future of intellectual subject indexing and we give an overview on related projects also aiming at digitizing and economizing this challenging process.

  6. Distinct features of C/N balance regulation in Prochlorococcus sp. strain MIT9313.

    Science.gov (United States)

    Domínguez-Martín, María Agustina; López-Lozano, Antonio; Rangel-Zúñiga, Oriol Alberto; Díez, Jesús; García-Fernández, José Manuel

    2018-02-01

    The abundance and significant contribution to global primary production of the marine cyanobacterium Prochlorococcus have made it one of the main models in marine ecology. Several conditions known to cause strong effects on the regulation of N-related enzymes in other cyanobacteria lacked such effect in Prochlorococcus. Prochlorococcus sp. strain MIT9313 is one of the most early-branching strains among the members of this genus. In order to further understand the C/N control system in this cyanobacterium, we studied the effect of the absence of three key elements in the ocean, namely N, P and Fe, as well as the effect of inhibitors of the N assimilation or photosynthesis on the N metabolism of this strain. Furthermore, we focused our work in the effect of ageing, as the age of cultures has clear effects on the regulation of some enzymes in Prochlorococcus. To reach this goal, expression of the main three regulators involved in N assimilation in cyanobacteria, namely ntcA, glnB and pipX, as well as that of icd (encoding for isocitrate dehydrogenase) were analysed. Our results show that the control of the main proteins involved in the C/N balance in strain MIT9313 differs from other model Prochlorococcus strains. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  7. Ustekinumab in der Therapie der Pustulosis palmoplantaris - Eine Fallserie mit neun Patienten.

    Science.gov (United States)

    Buder, Valeska; Herberger, Katharina; Jacobi, Arnd; Augustin, Matthias; Radtke, Marc Alexander

    2016-11-01

    Die Pustulosis palmoplantaris ist eine chronisch entzündliche Hauterkrankung, die mit bedeutenden Einschränkungen der Lebensqualität und der Belastbarkeit einhergeht. Aufgrund von Zulassungsbeschränkungen und einem häufig therapierefraktären Verlauf sind die Behandlungsmöglichkeiten limitiert. Nach zuvor frustranen Therapien erhielten 9 Patienten mit Pustulosis palmoplantaris nach Ausschluss einer latenten Tuberkulose Ustekinumab (45 mg Ustekinumab bei  100 kg KG) in Woche 0, 4, 12 und 24. Reguläre Visiten erfolgten nach 4 und 12 Wochen, im weiteren Verlauf alle 12 Wochen. Das Durchschnittsalter bei Therapiebeginn betrug 48 Jahre. Drei Patienten waren männlich. Bei n  =  4 Patienten (44,4 %) wurde eine Verbesserung um 75 % des Palmoplantar-Psoriasis-Area-Severity-Index (PPPASI) erreicht. Insgesamt verbesserte sich der PPPASI nach 24 Wochen durchschnittlich um 71,6 %. Eine komplette Abheilung zeigte sich bei n  =  2 Patienten nach 24 Wochen. Bis auf lokale Injektionsreaktionen und leichte Infekte wurden keine unerwünschten Wirkungen beobachtet. Die Fallserie ist ein weiterer Beleg für die Wirksamkeit und Verträglichkeit von Ustekinumab in der Therapie der Pustulosis palmoplantaris. Zur Beurteilung der Langzeitwirkung und -sicherheit sowie der Wirksamkeit einer intermittierenden Therapie sind kontrollierte Studiendaten sowie Beobachtungen im Rahmen von Patientenregistern notwendig. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

  8. MIT-Skywalker: considerations on the Design of a Body Weight Support System.

    Science.gov (United States)

    Gonçalves, Rogério Sales; Krebs, Hermano Igo

    2017-09-06

    To provide body weight support during walking and balance training, one can employ two distinct embodiments: support through a harness hanging from an overhead system or support through a saddle/seat type. This paper presents a comparison of these two approaches. Ultimately, this comparison determined our selection of the body weight support system employed in the MIT-Skywalker, a robotic device developed for the rehabilitation/habilitation of gait and balance after a neurological injury. Here we will summarize our results with eight healthy subjects walking on the treadmill without any support, with 30% unloading supported by a harness hanging from an overhead system, and with a saddle/seat-like support system. We compared the center of mass as well as vertical and mediolateral trunk displacements across different walking speeds and support. The bicycle/saddle system had the highest values for the mediolateral inclination, while the overhead harness body weight support showed the lowest values at all speeds. The differences were statistically significant. We selected the bicycle/saddle system for the MIT-Skywalker. It allows faster don-and-doff, better centers the patient to the split treadmill, and allows all forms of training. The overhead harness body weight support might be adequate for rhythmic walking training but limits any potential for balance training.

  9. Berechnung des Hochfrequenzverhaltens komplexer Strukturen mit der Methode gekoppelter Streuparameter – CSC

    Directory of Open Access Journals (Sweden)

    H.-W. Glock

    2004-01-01

    Full Text Available Es wird eine Methode zur Berechnung der Hochfrequenz-Eigenschaften komplexer Strukturen vorgestellt. Das Verfahren beruht auf der Zerlegung der Gesamtstruktur in einzelne einfachere Segmente, deren breitbandige S-Matrizen mit kommerziellen Programmen berechnet werden. Das Gesamtsystem kann von beliebiger Topologie sein, und die Zahl der die Segmente verkoppelnden Hohlleiter- Moden ist nicht begrenzt. Als Ergebnis steht bei offenen Strukturen deren vollständige S-Matrix, bei abgeschlossenen deren Resonanzeigenschaften zur Verfügung. Die theoretischen Grundlagen werden beschrieben und die Anwendung mit Beispielen aus dem Gebiet der Teilchenbeschleuniger und zu Eigenschaften schwach elliptisch geformter Resonatoren illustriert. A method called Coupled S-Parameter Calculation – CSC is described which is used to calculate the rf properties of complex structures, i.e. either their scattering (devices with ports or their resonance properties. The method is based on the segmentation of the entire system into sections being less complex, the external calculation of the section’s broadband S-matrices, and a combination scheme, which is applicable to any topology and number of modes. The method’s principle is described. Examples from the field of particle accelerator cavities and about the properties of weakly elliptical resonators are given.

  10. Development of a Fissile Materials Irradiation Capability for Advanced Fuel Testing at the MIT Research Reactor

    International Nuclear Information System (INIS)

    Hu Linwen; Bernard, John A.; Hejzlar, Pavel; Kohse, Gordon

    2005-01-01

    A fissile materials irradiation capability has been developed at the Massachusetts Institute of Technology (MIT) Research Reactor (MITR) to support nuclear engineering studies in the area of advanced fuels. The focus of the expected research is to investigate the basic properties of advanced nuclear fuels using small aggregates of fissile material. As such, this program is intended to complement the ongoing fuel evaluation programs at test reactors. Candidates for study at the MITR include vibration-packed annular fuel for light water reactors and microparticle fuels for high-temperature gas reactors. Technical considerations that pertain to the design of the MITR facility are enumerated including those specified by 10 CFR 50 concerning the definition of a research reactor and those contained in a separate license amendment that was issued by the U.S. Nuclear Regulatory Commission to MIT for these types of experiments. The former includes limits on the cross-sectional area of the experiment, the physical form of the irradiated material, and the removal of heat. The latter addresses experiment reactivity worth, thermal-hydraulic considerations, avoidance of fission product release, and experiment specific temperature scrams

  11. Pump-turbines with constant flow direction; Pumpenturbinen mit gleicher Durchstroemrichtung

    Energy Technology Data Exchange (ETDEWEB)

    Mollenkopf, G. [Zentrale Forschung Engineering, KSB AG, Frankenthal (Germany)

    1997-12-31

    This research project was sponsored by the federal ministry of science and technology BMFT (product owner: New Materials and Chemical Technologies - NMT). Its aim was to develop a novel unit that can work both as a pump and a turbine with a constant flow direction through internal blade adjustment. This specifically high-speed pump-turbine is suited for plants where a liquid in one case needs to be hauled against a rising pressure and where, in another case, there is a pressure drop in the same direction. So far, either a separate pump and turbine each are used which are temporarily stopped, involving corresponding effort, or - almost as a rule - the turbine is dispensed with, so that the energy locked up in the pressure drop goes unused. (orig.) [Deutsch] Die Zielsetzung unseres Forschungsvorhabens, das vom BMFT (Produkttraeger: Neue Materialien und Chemische Technologien - NMT) gefoerdert wird, war die Entwicklung eines neuartigen Aggregats, das durch interne Schaufelverstellung in der Lage ist, sowohl als Pumpe als auch als Turbine mit gleichbleibender Durchstroemrichtung zu arbeiten. Diese spezifisch schnellaeufige Pumpturbine kommt fuer Anlagen in Frage, in denen eine Fluessigkeit im einen Fall gegen einen anstehenden Druck gefoerdert werden muss und im anderen Fall in gleicher Richtung ein Druckgefaelle zur Verfuegung steht. Entweder werden bisher getrennt aufgestellte Pumpen und Turbinen mit zeitweisem Stillstand und entsprechendem Aufwand eingesetzt oder es wird - fast in der Regel - auf die Turbine und damit auf die im Druckgefaelle enthaltene Energie verzichtet. (orig.)

  12. Identifikationsverfahren zur Analyse von EEG-Signalen bei Epilepsie mit Reaktions-Diffusions Netzwerken

    Science.gov (United States)

    Gollas, F.; Tetzlaff, R.

    2007-06-01

    Partielle Differentialgleichungen des Reaktions-Diffusions-Typs beschreiben Phänomene wie Musterbildung, nichtlineare Wellenausbreitung und deterministisches Chaos und werden oft zur Untersuchung komplexer Vorgänge auf den Gebieten der Biologie, Chemie und Physik herangezogen. Zellulare Nichtlineare Netzwerke (CNN) sind eine räumliche Anordnung vergleichsweise einfacher dynamischer Systeme, die eine lokale Kopplung untereinander aufweisen. Durch eine Diskretisierung der Ortsvariablen können Reaktions-Diffusions-Gleichungen häufig auf CNN mit nichtlinearen Gewichtsfunktionen abgebildet werden. Die resultierenden Reaktions-Diffusions-CNN (RD-CNN) weisen dann in ihrer Dynamik näherungsweise gleiches Verhalten wie die zugrunde gelegten Reaktions-Diffusions-Systeme auf. Werden RD-CNN zur Identifikation neuronaler Strukturen anhand von EEG-Signalen herangezogen, so besteht die Möglichkeit festzustellen, ob das gefundene Netzwerk lokale Aktivität aufweist. Die von Chua eingeführte Theorie der lokalen Aktivität Chua (1998); Dogaru und Chua (1998) liefert eine notwendige Bedingung für das Auftreten von emergentem Verhalten in zellularen Netzwerken. Änderungen in den Parametern bestimmter RD-CNN könnten auf bevorstehende epileptische Anfälle hinweisen. In diesem Beitrag steht die Identifikation neuronaler Strukturen anhand von EEG-Signalen durch Reaktions-Diffusions-Netzwerke im Vordergrund der dargestellten Untersuchungen. In der Ergebnisdiskussion wird insbesondere auch die Frage nach einer geeigneten Netzwerkstruktur mit minimaler Komplexität behandelt.

  13. Modern engine management using neuronal nets; Modernes Motormanagement mit Neuronalen Netzen

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, R O

    1998-07-01

    The author focuses on the theoretical analysis, description and extension of neuronal control technology and its applications in engine management. Definitions and methods are presented for forward and recurrent nets. The fundamentals of control technology are described, and neuronal methods for modelling and control are presented. The first part of the report ends with a stability calculation which leads to the extension of existing learning methods. The second part discusses neuronal methods in the control of an external combustion engine. The investigated engine system is described, the combustion process is analyzed, and the fundamentals of engine management are presented. Ignition point and momentum control are presented as examples to illustrate the applicability of neuronal methods. [German] Das Ziel der vorliegenden Arbeit war die theoretische Aufarbeitung, Darstellung und Erweiterung der neuronalen Regelungstechnik und ihre moegliche Anwendung im Motormanagement. Im grundlagenorientierten Teil wurden zuerst die wichtigsten Definitionen und Verfahren fuer vorwaertsgekoppelte und rekurrente Netze praesentiert. Anschliessend folgte eine kurze Einfuehrung in die Regelungstechnik, bevor ausfuehrlich verschiedene Methoden zur neuronalen Modellierung und Regelung vorgestellt wurden. Der erste Teil der Arbeit endete mit einer Stabilitaetsbetrachtung und einer darauf aufbauenden Erweiterung der bestehenden Lernverfahren. Der zweite Teil beschaeftigte sich mit der Anwendung der neuronalen Methoden in der Steuerung eines Verbrennungsmotors. Zur Motivation wurde das betrachtete System genau beschrieben, die Verbrennung analysiert und die Grundlagen des Motormanagements vorgestellt. Beispielhaft wurden im letzten Kapitel die Zuendzeitpunkt- und die Momentenregelung herausgegriffen und an ihnen die Anwendbarkeit der neuronalen Verfahren aufgezeigt. (orig.)

  14. The MIT HEDP Accelerator Facility for Diagnostic Development for OMEGA, Z, and the NIF

    Science.gov (United States)

    Sio, H.; Gatu Johnson, M.; Birkel, A.; Doeg, E.; Frankel, R.; Kabadi, N. V.; Lahmann, B.; Manzin, M.; Simpson, R. A.; Parker, C. E.; Sutcliffe, G. D.; Wink, C.; Frenje, J. A.; Li, C. K.; Seguin, F. H.; Petrasso, R. D.; Leeper, R.; Hahn, K.; Ruiz, C. L.; Sangster, T. C.; Hilsabeck, T.

    2017-10-01

    The MIT HEDP Accelerator Facility utilizes a 135-keV, linear electrostatic ion accelerator; DT and DD neutron sources; and two x-ray sources for development and characterization of nuclear diagnostics for OMEGA, Z, and the NIF. The accelerator generates DD and D3He fusion products through the acceleration of D+ ions onto a 3He-doped Erbium-Deuteride target. Accurately characterized fusion product rates of around 106 s- 1 are routinely achieved. The DT and DD neutron sources generate up to 6×108 and 1×107 neutrons/s, respectively. One x-ray generator is a thick-target W source with a peak energy of 225 keV and a maximum dose rate of 12 Gy/min; the other uses Cu, Mo, or Ti elemental tubes to generate x-rays with a maximum energy of 40 keV. Diagnostics developed and calibrated at this facility include CR-39-based charged-particle spectrometers, neutron detectors, and the particle Time-Of-Flight (pTOF) and Magnetic PTOF CVD-diamond-based bang time detectors. The accelerator is also a valuable hands-on tool for graduate and undergraduate education at MIT. This work was supported in part by the U.S. DoE, SNL, LLE and LLNL.

  15. Temperature measurement in practice with resistance thermometers and thermocouples; Temperaturmesspraxis mit Widerstandsthermometern und Thermoelementen

    Energy Technology Data Exchange (ETDEWEB)

    Irrgang, K.; Michalowsky, L (eds.)

    2004-07-01

    The book addresses students of science and engineering, engineers and practicians in research and industry who are interested in temperature measurements and thermal processes in the temperature range between a few K and over 3200 K. For the first time ever, temperature sensors are classified on the basis of heat transport and heat transfer to the sensor as related to the technological aspects of sensor stress. This includes physical and materials-related fundamentals, materials selection, sensor design and optimisation, error analysis, as well as the analysis of economically relevant applications of electrical temperature measurement in thermal processes. [German] Dieses Buch wendet sich an Studenten der Natur- und Technikwissenschaften, Ingenieure und Hochschulabsolventen in der Forschung und Industrie, die sich mit Temperaturmessungen und thermischen Prozessen im Temperaturbereich von wenigen Kelvin bis zu ueber 3200 K befassen. Der neue Titel wird sich gegenueber bekannten Standards auf diesem Gebiet dadurch auszeichnen, dass eine Klassifizierung der Temperaturfuehler abhaengig vom Waermetransport und den Waermeuebergaengen zum Sensor in Verbindung mit den technologischen Aspekten zu den konkreten Beanspruchungen der Fuehler in der Anwendung vorgenommen wird. Dieser hohe Anspruch schliesst physikalische und werkstoffwissenschaftliche Grundlagen zur Systemloesung, der Werkstoffauswahl, zur Auslegung und Optimierung des Fuehlerdesigns und der notwendigen Fehlerbetrachtung ebenso ein, wie die Analyse volkswirtschaftlich bedeutsamer Anwendungen der elektrischen Temperaturmesstechnik in thermischen Prozessen. (orig.)

  16. High-speed pyrolysis with circulating heat carriers; Schnell-Pyrolyse mit zirkulierenden Waermetraegern

    Energy Technology Data Exchange (ETDEWEB)

    Schmalfeld, J; Albrecht, J; Solmaz, S; Zentner, U [Lurgi Energie und Umwelt GmbH, Frankfurt am Main (Germany)

    1998-09-01

    Yields and product compositions of pyrolysis reactions depend on the mode of heat supply, the temperature level, and the time of residue at reaction temperature. Using hot circulating granular materials mixed with solid or liquid materials (e.g. biogenic or hydrocarbon-rich residues and waste materials or refinery residues), the following important processes can be investigated: Separation of pyrolysis reaction and heat supply - accurate, optimal temperature levels for pyrolysis, e.g. between 5000 and 850 degrees centigrade - undiluted, unmixed pyrolysis gas - short times of residue of the pyrolysis gas for suppression of secondary reactions. (orig.) [Deutsch] Ausbeuten und Produktzusammensetzung von Pyrolyse-Reaktionen werden weitestgehend durch die Art und Weise der Waermezufuhr, das Temperaturniveau und die Verweilzeit bei Reaktionstemperatur bestimmt. Mit Hilfe des Prinzips heisser, umlaufender, koerniger Waermetraeger in Vermischung - fuer die Pyrolyse-Reaktion - mit festen oder fluessigen Einsatzstoffen (z.B. biogene oder kohlenwasserstoffreiche Rest-/Abfallstoffe, Raffinerie-Rueckstaende) lassen sich folgende wichtige, haeufig gewuenschte Vorgaenge realisieren: - Trennung von Pyrolyse-Reaktion und Waermeversorgung - Temperaturgenaue Pyrolyse-Reaktion auf gewuenschtem, optimalem Niveau waehlbar zwischen z.B. 5000 C und 850 C - Erhalt eines unverduennten, unvermischten Pyrolysegases - Kurze Verweilzeiten des Pyrolysegases zur Unterdrueckung von Sekundaerreaktionen. (orig.)

  17. A MIT-Based Nonlinear Adaptive Set-Membership Filter for the Ellipsoidal Estimation of Mobile Robots' States

    Directory of Open Access Journals (Sweden)

    Dalei Song

    2012-10-01

    Full Text Available The adaptive extended set-membership filter (AESMF for nonlinear ellipsoidal estimation suffers a mismatch between real process noise and its set boundaries, which may result in unstable estimation. In this paper, a MIT method-based adaptive set-membership filter, for the optimization of the set boundaries of process noise, is developed and applied to the nonlinear joint estimation of both time-varying states and parameters. As a result of using the proposed MIT-AESMF, the estimation effectiveness and boundary accuracy of traditional AESMF are substantially improved. Simulation results have shown the efficiency and robustness of the proposed method.

  18. Mitä tänään on tarjolla?” : opiskelijaruokailu laadusta mielikuviin

    OpenAIRE

    Partanen, Elina

    2008-01-01

    Työn tavoitteena oli selvittää, mitä opiskelijat yleensä syövät lounaalla opiskelijaravintolassa ja mitä mieltä he olivat tarjotusta lounasruuasta. Jyväskylän ammattikorkeakoululla on viisi eri ruokapalveluiden tarjoajaa, ja jokaisella on hieman toisistaan poikkeava liikekonsepti. Tutkimus toteutettiin sähköpostikyselynä Digium-ohjelman avulla ammattikorkeakoulun eri alojen opiskelijoille. Kyselyyn oli mahdollista vastata 8.4.2008 – 22.4.2008 välisenä aikana. Kyselyyn vastasi 341. Kyselyn tul...

  19. Test calculations of physical parameters of the TRX,BETTIS and MIT critical assemblies according to the TRIFON program

    International Nuclear Information System (INIS)

    Kochurov, B.P.

    1980-01-01

    Results of calculations of physical parameters characterizing the TRX, MIT and BETTIS critical assemblies obtained according to the program TRIFON are presented. The program TRIFON permits to calculate the space-energy neutron distribution in the multigroup approximation in a multizone cylindrical cell. Results of comparison of the TRX, BETTIS and MIT crytical assembly parameters with experimental data and calculational results according to the Monte Carlo method are presented as well. Deviations of the parameters are in the range of 1.5-2 of experimental errors. Data on the interference of uranium 238 levels in the resonant neutron absorption in the cell are given [ru

  20. Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains*

    Science.gov (United States)

    Guo, Emily Z.; Xu, Zhaohui

    2015-01-01

    The endosomal sorting complex required for transport (ESCRT) machinery is responsible for membrane remodeling in a number of biological processes including multivesicular body biogenesis, cytokinesis, and enveloped virus budding. In mammalian cells, efficient abscission during cytokinesis requires proper function of the ESCRT-III protein IST1, which binds to the microtubule interacting and trafficking (MIT) domains of VPS4, LIP5, and Spartin via its C-terminal MIT-interacting motif (MIM). Here, we studied the molecular interactions between IST1 and the three MIT domain-containing proteins to understand the structural basis that governs pairwise MIT-MIM interaction. Crystal structures of the three molecular complexes revealed that IST1 binds to the MIT domains of VPS4, LIP5, and Spartin using two different mechanisms (MIM1 mode versus MIM3 mode). Structural comparison revealed that structural features in both MIT and MIM contribute to determine the specific binding mechanism. Within the IST1 MIM sequence, two phenylalanine residues were shown to be important in discriminating MIM1 versus MIM3 binding. These observations enabled us to deduce a preliminary binding code, which we applied to provide CHMP2A, a protein that normally only binds the MIT domain in the MIM1 mode, the additional ability to bind the MIT domain of Spartin in the MIM3 mode. PMID:25657007

  1. Distinct mechanisms of recognizing endosomal sorting complex required for transport III (ESCRT-III) protein IST1 by different microtubule interacting and trafficking (MIT) domains.

    Science.gov (United States)

    Guo, Emily Z; Xu, Zhaohui

    2015-03-27

    The endosomal sorting complex required for transport (ESCRT) machinery is responsible for membrane remodeling in a number of biological processes including multivesicular body biogenesis, cytokinesis, and enveloped virus budding. In mammalian cells, efficient abscission during cytokinesis requires proper function of the ESCRT-III protein IST1, which binds to the microtubule interacting and trafficking (MIT) domains of VPS4, LIP5, and Spartin via its C-terminal MIT-interacting motif (MIM). Here, we studied the molecular interactions between IST1 and the three MIT domain-containing proteins to understand the structural basis that governs pairwise MIT-MIM interaction. Crystal structures of the three molecular complexes revealed that IST1 binds to the MIT domains of VPS4, LIP5, and Spartin using two different mechanisms (MIM1 mode versus MIM3 mode). Structural comparison revealed that structural features in both MIT and MIM contribute to determine the specific binding mechanism. Within the IST1 MIM sequence, two phenylalanine residues were shown to be important in discriminating MIM1 versus MIM3 binding. These observations enabled us to deduce a preliminary binding code, which we applied to provide CHMP2A, a protein that normally only binds the MIT domain in the MIM1 mode, the additional ability to bind the MIT domain of Spartin in the MIM3 mode. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  2. The Mysterious Fall of Soeharto: A Genre Analysis of Richard Mann’s Plots and Schemes that Brought Down Soeharto (PSBDS

    Directory of Open Access Journals (Sweden)

    Sugeng Purwanto

    2012-12-01

    Full Text Available The real cause of Soeharto’s fall from the Indonesian presidency remains a mystery. Richard Mann (1998 launched three significant rhetorical questions: (a Was President Soeharto toppled by student demonstrators and people’s power? (b Was he brought down by the withdrawal of support from the United States? (c Or, was his sudden fall brought about by all of the two plus large doses of Oriental plotting and scheming? This article attempts to analyze Richard Mann’s PSBDS in terms of its macrostructure in order to find out the real cause of Soeharto’s fall. The analysis is substantiated by different resources as linguistic evidences, to justify the validity of the findings. The study revealed a proposition that critical reading is the key to successful comprehension of a text which may include a crosschecking with other resources, a careful identification of the generic structure of a text, and paying attention to how an author positions his or her readers. The article concludes, that in fact, Soeharto resigned from presidency on his own wisdom in order to avoid more bloodshed in Indonesian dreamland.

  3. PET-Studies in parkinson's disease; Untersuchungen mit der Positronen-Emissions-Tomographie (PET) bei Patienten mit Morbus Parkinson

    Energy Technology Data Exchange (ETDEWEB)

    Schwarz, J. [Klinik fuer Neurologie, Univ. Leipzig (Germany)

    2002-09-01

    Positron-emission-tomography (PET) has enabled to study the metabolism and blood flow in specific brain areas. Besides, there is a variety of radiotracers that allow quantification of the function of distinct molecules. In respect to Parkinson's disease, PET allowed for the first time to assess the number of dopaminergic neurons in vivo. Thus, helping confirming a dopaminergic deficit, measuring disease progression and also help to determine the function of dopaminergic grafts. Current research has shifted to determine the role of related neurotransmitter systems in the pathophysiology of Parkinson's disease. (orig.) [German] Die positronen-emissions-tomographie (PET) bietet neben der Messung von Metabolismus und Blutfluss die Moeglichkeit der Darstellung von einzelnen Molekuelen. Bei Patienten mit Morbus Parkinson hat es diese Technik erstmals erlaubt, die Anzahl der dopaminergen Neurone zu quantifizieren, wodurch die Diagnose gesichert, die Progression der Erkrankung beurteilt und auch das Anwachsen von Implantaten beurteilt werden kann. Die PET hat einen wesentlichen Beitrag zu unserem heutigen Wissen ueber die Pathophysiologie dieser Erkrankung beigetragen. (orig.)

  4. Understanding the Self-Directed Online Learning Preferences, Goals, Achievements, and Challenges of MIT OpenCourseWare Subscribers

    Science.gov (United States)

    Bonk, Curtis J.; Lee, Mimi Miyoung; Kou, Xiaojing; Xu, Shuya; Sheu, Feng-Ru

    2015-01-01

    This research targeted the learning preferences, goals and motivations, achievements, challenges, and possibilities for life change of self-directed online learners who subscribed to the monthly OpenCourseWare (OCW) e-newsletter from MIT. Data collection included a 25-item survey of 1,429 newsletter subscribers; 613 of whom also completed an…

  5. TAF-4 is required for the life extension of isp-1, clk-1 and tpk-1 Mit mutants.

    Science.gov (United States)

    Khan, Maruf H; Ligon, Melissa; Hussey, Lauren R; Hufnal, Bryce; Farber, Robert; Munkácsy, Erin; Rodriguez, Amanda; Dillow, Andy; Kahlig, Erynn; Rea, Shane L

    2013-10-01

    While numerous life-extending manipulations have been discovered in the nematode Caenorhabditis elegans, one that remains most enigmatic is disruption of oxidative phosphorylation. In order to unravel how such an ostensibly deleterious manipulation can extend lifespan, we sought to identify the ensemble of nuclear transcription factors that are activated in response to defective mitochondrial electron transport chain (ETC) function. Using a feeding RNAi approach, we targeted over 400 transcription factors and identified 15 that, when reduced in function, reproducibly and differentially altered the development, stress response, and/or fecundity of isp-1(qm150) Mit mutants relative to wild-type animals. Seven of these transcription factors--AHA-1, CEH-18, HIF-1, JUN-1, NHR-27, NHR-49 and the CREB homolog-1 (CRH-1)-interacting protein TAF-4--were also essential for isp-1 life extension. When we tested the involvement of these seven transcription factors in the life extension of two other Mit mutants, namely clk-1(qm30) and tpk-1(qm162), TAF-4 and HIF-1 were consistently required. Our findings suggest that the Mit phenotype is under the control of multiple transcriptional responses, and that TAF-4 and HIF-1 may be part of a general signaling axis that specifies Mit mutant life extension.

  6. Validation of the Omron MIT Elite blood pressure device in a pregnant population with large arm circumference.

    Science.gov (United States)

    James, Lauren; Nzelu, Diane; Hay, Anna; Shennan, Andrew; Kametas, Nikos A

    2017-04-01

    The aim of this study was to evaluate the accuracy of the Omron MIT Elite automated device in pregnant women with an arm circumference of or above 32 cm, using the British Hypertension Society validation protocol. Blood pressure was measured sequentially in 46 women of any gestation requiring the use of a large cuff (arm circumference ≥32 cm) alternating between the mercury sphygmomanometer and the Omron MIT Elite device. The Omron MIT Elite achieved an overall D/D grade with a mean of the device-observer difference being 7.17±6.67 and 9.31±6.59 for systolic and diastolic blood pressure respectively. Interobserver accuracy was 94.6% for systolic and 95% for diastolic readings within 5 mmHg. The Omron MIT Elite overestimates blood pressure and has failed the British Hypertension Society protocol requirements. Therefore, it cannot be recommended for use in pregnant women with an arm circumference of or above 32 cm.

  7. TM-INES2: The 2nd Tokyo Tech-MIT symposium on innovative nuclear energy systems. Presentation materials

    International Nuclear Information System (INIS)

    2007-07-01

    The symposium of the title was held with four technical sessions; Innovative fast reactors, Advances in heat transfer, Nuclear hydrogen and synthetic fuels, Technologies for closing fuel cycle with 70 participants including 13 persons of MIT guests and 26 oral presentations in addition to a student poster session and the special educational session with over 150 participants. (J.P.N.)

  8. 76 FR 31230 - Safety Zone; M.I.T.'s 150th Birthday Celebration Fireworks, Charles River, Boston, MA

    Science.gov (United States)

    2011-05-31

    ...-AA00 Safety Zone; M.I.T.'s 150th Birthday Celebration Fireworks, Charles River, Boston, MA AGENCY... regulated area on the Charles River around the fireworks launch barge during the fireworks display... portions of the Charles River during a fireworks display. This rule will not have a significant economic...

  9. Wie gehen wir in der Vermittlung des Deutschen als Fremdsprache mit sprachlicher Qualität um?

    DEFF Research Database (Denmark)

    Colliander, Peter

    2011-01-01

    In der Pädagogik/Didaktik des Deutschen als Fremdsprache wird die erste Dichotomie erfahrungsgemäß in den Mittelpunkt gestellt, was zu einem rigiden Umgang mit dem Begriff „sprachliche Qualität“ führt, einem Umgang, der für die Motivation der Lerner nicht förderlich ist. Dieser ersten Dichotomie...

  10. Mathematical modelling of the performance of hydrodynamic couplings using hybrid models; Mathematische Modellierung des Betriebsverhaltens hydrodynamischer Kupplungen mit hybriden Modellansaetzen

    Energy Technology Data Exchange (ETDEWEB)

    Jaschke, P.

    2000-02-01

    Mathematical models of the dynamic performance of hydrodynamic couplings are developed using hybrid modelling, i.e. a combination of analytical physical modelling and black box identification. The models developed were verified by measurements on a model powertrain. [German] In dieser Arbeit werden mit Hilfe der hybriden Modellierung mathematische Modelle zur Beschreibung des dynamischen Betriebsverhaltens hydrodynamischer Kupplungen ermittelt. Die Hybride Modellierung stellt eine Kombination der analytisch physikalischen Modellierung und der Black-Box-Identifikation dar. Diese Modellierungsart ist ausgewaehlt worden, um die Vorteile der analytisch physikalischen Modellierung und der Black-Box-Identifikation hydrodynamischer Kupplungen zu verbinden und deren Nachteile gering zu halten. Auf dieser Basis ist eine Vorgehensweise vorgestellt worden, die die Ermittlung der Modelle mit wenig Aufwand ermoeglicht. Mit Hilfe der Modelltheorie wird gezeigt, wie die ermittelten mathematischen Modelle zur Simulation des dynamischen Betriebsverhaltens geometrisch aehnlicher Kupplungen unterschiedlicher Baugroessen verwendet werden koennen. Darueber hinaus wird dargelegt, wie die ermittelten Modelle mit Modellen anderer Antriebsstrangelemente gekoppelt werden koennen, um Antriebsstrangsimulationen zu ermoeglichen. Verifikationsmessungen an einem Modellantriebsstrang verdeutlichen die Guete und Verwendbarkeit der mathematischen Modelle. (orig.)

  11. Development of a Charged Particle Microbeam for Single-Particle Subcellular Irradiations at the MIT Laboratory for Accelerator Beam Application

    International Nuclear Information System (INIS)

    Yanch, Jacquelyn C.

    2004-01-01

    The development of a charged particle microbeam for single particle, subcellular irradiations at the Massachusetts Institute of Technology Laboratory for Accelerator Beam Applications (MIT LABA) was initiated under this NEER aeard. The Microbeam apparatus makes use of a pre-existing electrostatic accelerator with a horizontal beam tube

  12. Interactive Web-Based and Hands-On Engineering Education: A Freshman Aerospace Design Course at MIT.

    Science.gov (United States)

    Newman, Dava J.

    "Introduction to Aerospace and Design" is a 3-hour per week freshman elective course at Massachusetts Institute of Technology (MIT) that culminates in a Lighter-Than-Air (LTA) vehicle design competition, exposing freshmen to the excitement of aerospace engineering design typically taught in the junior or senior years. In addition to the…

  13. District heat, energy for fore-sighted people. Proceedings; Energie fuer Menschen mit Weitblick. Vortragsband

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    The proceedings volume contains a great part of the papers presented, but some are represented only by copies of the overheads which accompanied the papers. The lecture meeting was devoted to the following major topics: Economical and safe supply of district heat, outlook on the future of the district heat supply industry in a liberalized market, customer relationship management taking into account contracting, information and communication via call centers, and other forms of guidance for decision making.(GL) [German] Vortraege vorliegend teils als Manuskript, teils als Folien mit folgenden Schwerpunkten: Die wirtschaftliche und sichere Versorgung durch Fernwaerme, die Zukunft der Fernwaerme im liberalisierten Markt, der Weg zum Kunden im Hinblick auf Contracting, Kommunikation, Betreuung sowie Beratung und Entscheidungsfindung.(GL)

  14. Bestimmung der Mas'se des neutralen Bs-Mesons mit dem ALEPH-Experiment

    CERN Document Server

    Stehle, M

    2001-01-01

    Gegenstand der vorliegenden Arbeit ist die Bestimmung der Masse des neutralen Bs-Mesons. Dazu wurden B~-Mesonen in den beiden Zerfallskanalen B~ -+ J/W P und B~ -+ W(2S) P rekonstruiert, wobei die Subresonanzen in den Zerfallsmoden J /w -+ l+ l-, W(2S) -+ l+ l- und P -+ K+ K- untersucht wurden. Diese beiden Kanale werden auf Grund ihrer eindeutigen Signatur auch als "goldene Kanale" bezeichnet und eignen sich deshalb sehr gut fur eine exklusive Rekonstruktion, wie sie hier angewendet wurde. Grundlage der Analyse waren ca. 4 Millionen hadronische ZO-Zerfalle, die in den Jahren 1991 1995 mit dem ALEPH-Detektor am e+e--Speicherring LEP am CERN aufgezeichnet wurden. Die zwischenzeitliche Reprozessierung der Daten ermoglichte eine prazisere und effizientere Rekonstruktion als das in fruheren Messungen der Fall war. Wegen der niedrigen Verzweigungsverhaltnisse der untersuchten Zerfallsmoden wurden nur wenige einzelne Ereignisse in den Daten erwartet. Die selektierten Kandidaten wurden durch Schnitte in mehreren Ere...

  15. MIT-NASA/KSC space life science experiments - A telescience testbed

    Science.gov (United States)

    Oman, Charles M.; Lichtenberg, Byron K.; Fiser, Richard L.; Vordermark, Deborah S.

    1990-01-01

    Experiments performed at MIT to better define Space Station information system telescience requirements for effective remote coaching of astronauts by principal investigators (PI) on the ground are described. The experiments were conducted via satellite video, data, and voice links to surrogate crewmembers working in a laboratory at NASA's Kennedy Space Center. Teams of two PIs and two crewmembers performed two different space life sciences experiments. During 19 three-hour interactive sessions, a variety of test conditions were explored. Since bit rate limits are necessarily imposed on Space Station video experiments surveillance video was varied down to 50 Kb/s and the effectiveness of PI controlled frame rate, resolution, grey scale, and color decimation was investigated. It is concluded that remote coaching by voice works and that dedicated crew-PI voice loops would be of great value on the Space Station.

  16. Qualitative Forschung mit lebenslimitierend erkrankten Kindern und Jugendlichen: Hören wir richtig hin?

    Directory of Open Access Journals (Sweden)

    Claudia Oetting-Roß

    2016-05-01

    Full Text Available Der nachfolgende Beitrag diskutiert die Herausforderungen des Einbezugs von betroffenen Kindern und Jugendlichen in die qualitative Forschung zum Thema lebenslimitierende Erkrankungen insbesondere unter dem Blickwinkel der methodischen Gestaltung dieses Einbezugs. Hierfür wird zunächst die Lebens- und Versorgungssituation lebenslimitierend erkrankter Kinder und Jugendlicher dargestellt. Anschließend werden Ergebnisse aus empirischen Studien erläutert und im Hinblick auf die Herausforderungen einer Beteiligung erkrankter Kinder, Jugendlicher und ihrer Familien diskutiert. Als Ergebnis dieser Analyse erfolgt eine Zusammenfassung zentraler Diskussionsstränge. Zudem werden Strategien für eine sensible Integration von schwerkranken Kindern und Jugendlichen abgeleitet und auf der Basis bestehender Erfahrungen aus qualitativen Studien konkretisiert. Vor dem Hintergrund einer laufenden Studie mit lebenslimitierend erkrankten Kindern liefert der Beitrag Anregungen für die methodische Planung, Durchführung und Evaluation von entsprechenden Forschungsvorhaben. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1602241

  17. Die Struktur von schlankem Materialfluss mit Lean Production Kanban und Innovationen

    Science.gov (United States)

    Scheid, Wolf-Michael

    In der Literatur wird Materialfluss überwiegend in Spezialdisziplinen betrachtet, etwa der Steuerungslogik, der Logistiktechnik oder dem Supply Chain Management. Ein charakterisierendes Merkmal des Materialflusses ist jedoch, dass er sich aus vielfältigen Einzelbausteinen zusammensetzt, die alle harmonisch abgestimmt sein müssen. Die maximal erreichbare Effizienz wird nicht durch Höchstleistungen in dem einen oder anderen Spezialthema bestimmt, sondern durch das schwächste Glied im gesamten komplexen Netzwerk. Den Schnittstellen zwischen den betroffenen Fachbereichen in einem Unternehmen kommt hier eine ganz besondere Bedeutung zu: Erst ein harmonischer Einklang ermöglicht hohe Effektivität. Dies setzt umfassendes Verständnis für interdisziplinäre Notwendigkeiten, ein hohes Maß an Abstimmung mit den operativen Prozessen und letztlich einen einvernehmlichen Umgang und den Respekt vor den Problemstellungen des Anderen voraus.

  18. Eddy current testing system with integrated fluxgate magnetometer; Wirbelstrompruefsystem mit integriertem Fluxgate-Magnetometer

    Energy Technology Data Exchange (ETDEWEB)

    Kreutzbruck, M. v.; Allweins, K.; Heiden, C. [Giessen Univ. (Germany)

    2000-07-01

    The eddy current testing system described uses Foerster probes for low-frequency magnetic field detection. The major objective is to detect deep flaws in specimens/materials with good conductivity, such as aluminum. Deep flaws could be reliably detected using low excitation frequencies of a few 100 Hz and an evaluation software and data acquisition hardware matching the high dynamics of the Foerster probe. (orig./CB) [German] Es wurde ein Wirbelstromsystem auf der Basis von Foerstersonden zur niederfrequenten Magnetfelddetektion aufgebaut. Das Hauptaugenmerk hierbei lag auf der Detektion von tiefliegenden Fehlerstrukturen in gut leitfaehigen Pruefteilen, wie Aluminiumstrukturen. In Kombination mit einer an den hohen Dynamik bereich einer Foerstersonde angepassten Auswerteelektronik und Datenaufnahme konnten mittels niedrigen Anregungsfrequenzen von wenigen 100 Hz tiefliegende Fehlerstrukturen zuverlaessig detektiert werden. (orig.)

  19. Frequency-difference MIT imaging of cerebral haemorrhage with a hemispherical coil array: numerical modelling.

    Science.gov (United States)

    Zolgharni, M; Griffiths, H; Ledger, P D

    2010-08-01

    The feasibility of detecting a cerebral haemorrhage with a hemispherical MIT coil array consisting of 56 exciter/sensor coils of 10 mm radius and operating at 1 and 10 MHz was investigated. A finite difference method combined with an anatomically realistic head model comprising 12 tissue types was used to simulate the strokes. Frequency-difference images were reconstructed from the modelled data with different levels of the added phase noise and two types of a priori boundary errors: a displacement of the head and a size scaling error. The results revealed that a noise level of 3 m degrees (standard deviation) was adequate for obtaining good visualization of a peripheral stroke (volume approximately 49 ml). The simulations further showed that the displacement error had to be within 3-4 mm and the scaling error within 3-4% so as not to cause unacceptably large artefacts on the images.

  20. Polarized Electron Beams for Nuclear Physics at the MIT Bates Accelerator Center

    CERN Document Server

    Farkhondeh, Manouchehr; Franklin, Wilbur; Ihloff, Ernie; McAllister, Brian; Milner, Richard; North, William; Tschalär, C; Tsentalovich, Evgeni; Wang, Defa; Wang, Dong; Wang, Fuhua; Zolfaghari, Abbasali; Zwart, Townsend; van der Laan, Jan

    2005-01-01

    The MIT Bates Accelerator Center is delivering highly polarized electron beams to its South Hall Ring for use in Nuclear Physics Experiments. Circulating electron currents in excess of 200 mA with polarization of 70% are scattered from a highly polarized, but very thin atomic beam source deuterium target. At the electron source a compact diode laser creates photoemission of quasi-CW mA pulses of polarized electrons at low duty factors from a strained GaAs photocathode. Refurbished RF transmitters provide power to the 2856 MHz linac, accelerating the beam to 850 MeV in two passes before injection into the South Hall Ring. In the ring a Siberian snake serves to maintain a high degree of longitudinal polarization at the BLAST scattering target. A Compton laser back-scattering polarimeter measures the electron beam polarization with a statistical acuracy of 6% every 15 minutes.