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Sample records for ric pilgrim jane

  1. AsTeRICS.

    Science.gov (United States)

    Drajsajtl, Tomáš; Struk, Petr; Bednárová, Alice

    2013-01-01

    AsTeRICS - "The Assistive Technology Rapid Integration & Construction Set" is a construction set for assistive technologies which can be adapted to the motor abilities of end-users. AsTeRICS allows access to different devices such as PCs, cell phones and smart home devices, with all of them integrated in a platform adapted as much as possible to each user. People with motor disabilities in the upper limbs, with no cognitive impairment, no perceptual limitations (neither visual nor auditory) and with basic skills in using technologies such as PCs, cell phones, electronic agendas, etc. have available a flexible and adaptable technology which enables them to access the Human-Machine-Interfaces (HMI) on the standard desktop and beyond. AsTeRICS provides graphical model design tools, a middleware and hardware support for the creation of tailored AT-solutions involving bioelectric signal acquisition, Brain-/Neural Computer Interfaces, Computer-Vision techniques and standardized actuator and device controls and allows combining several off-the-shelf AT-devices in every desired combination. Novel, end-user ready solutions can be created and adapted via a graphical editor without additional programming efforts. The AsTeRICS open-source framework provides resources for utilization and extension of the system to developers and researches. AsTeRICS was developed by the AsTeRICS project and was partially funded by EC.

  2. What Jane Saw

    Directory of Open Access Journals (Sweden)

    Kate Singer

    2013-11-01

    Full Text Available Review of Professor Janine Barchas' "What Jane Saw?" a website that reconstructs Joshua Reynolds's 1813 retrospective art exhibit, which Jane Austen attended, with particular attention to the Regency social and cultural history depicted in Austen's novels.

  3. Health knowledge, attitude and practice among Iranian pilgrims.

    Science.gov (United States)

    Tabatabaei, Aminreza; Mortazavi, Seyyed Mostafa; Shamspour, Navvab; Shushtarizadeh, Naser

    2015-02-01

    Iran has the highest number of Umrah pilgrims among Islamic countries. Health care plays a major role in fulfilling the Umrah rites. Pilgrims' health situation depends on their health knowledge, attitude, and practice (KAP). In this study, we aimed to determine the health KAP among Iranian Umrah pilgrims. In this cross-sectional study, 157 Iranian Umrah pilgrims were randomly selected in Mecca, Saudi Arabia in June 2011. Data were collected using a questionnaire. The questionnaire consisted of demographic information (sex, age, degree of education, and resource of health knowledge), health knowledge (5 questions), health attitude (5 questions) and health practice (10 questions). Level of knowledge were very low in 12.1%, low in 25.2%, average in 38.1%, good in 20.4% and very good in 4.2% of respondents. Mean and standard deviation of attitude score was 18.58 ± 2.20 out of 25 (ranged between 13.00 and 25.00). The pilgrims were given 74.2 % out of total score. The Mean and standard deviation of practice score was 8.19 ± 1.32 out of 10 (ranged between 3 and 10). Although the old and low educated pilgrims had little knowledge of health tips, they had a good health attitude and practice. Educational strategy to improve knowledge regarding health-related problems and to develop health practices among pilgrims is needed.

  4. Influenza vaccination among Saudi Hajj pilgrims: Revealing the uptake and vaccination barriers.

    Science.gov (United States)

    Alfelali, Mohammad; Barasheed, Osamah; Badahdah, Al-Mamoon; Bokhary, Hamid; Azeem, Mohammed I; Habeebullah, Turki; Bakarman, Marwan; Asghar, Atif; Booy, Robert; Rashid, Harunor

    2018-04-12

    Hajj is the world's largest annual mass gathering that attracts two to three million Muslims from around the globe to a religious assemblage in Makkah, Saudi Arabia. The risk of acquisition and transmission of influenza among Hajj pilgrims is high. Therefore, influenza vaccination is recommended, and was monitored frequently among pilgrims from different countries. However, the vaccination uptake among Saudi pilgrims has not been assessed in recent years. This analysis aims to evaluate influenza vaccine uptake among Saudi Hajj pilgrims, and identify the key barriers to vaccination. Data on influenza vaccination were obtained from Saudi pilgrims who took part in a large trial during the Hajj of 2013, 2014 and 2015. Pilgrims were met and recruited in Mina, Makkah during the peak period of Hajj and were asked to complete a baseline questionnaire that recorded their influenza vaccination history, including reason(s) for non-receipt of vaccine. A total of 6974 Saudi pilgrims aged between 18 and 95 (median 34) years were recruited; male to female ratio was 1:1.2. Of the total, 90.8% declared their influenza vaccination history, 51.3% of them reported receiving influenza vaccine before travel to Hajj. The vaccination rates for the years 2013, 2014 and 2015 were 21.4%, 48.2% and 58.1%, respectively (P Saudi Hajj pilgrims is increasing over years but still needs further improvement. Lack of awareness and misperceptions are the main barriers. Education of Saudi pilgrims and health professionals is required to raise awareness about influenza vaccination. Further studies are needed to understand pilgrims' misperceptions. Copyright © 2018 Elsevier Ltd. All rights reserved.

  5. Pre-travel health seeking practices of Umrah pilgrims departing from Assiut International Airport, Egypt.

    Science.gov (United States)

    Aziz, Mirette M; Abd El-Megeed, Hosnia S; Abd Ellatif, Mennat Allah M

    2018-04-22

    to assess the health seeking practices and their determinants among Umrah pilgrims departing from Assiut international Airport. We interviewed 300 pilgrims departing from Assiut International Airport while they were in the departure lounge, using a semi-structured questionnaire. Only 60%, 46.3% and 46.3% of Umrah pilgrims believed in importance of pre-travel vaccination, seeking health information, and health examination, respectively. The most frequently practiced pre-travel health related behaviour was getting vaccinated (56.3%), as compared to much lower frequencies of seeking health information (24%) or having a clinical health examination (26.7%). Private clinics, internet and the tourism companies were the main sources of health information of the pilgrims. Positive attitude of pilgrims about health seeking practices, the perception of health risk of travelling to Hajj/Umrah and having a chronic disease were the predictors of pre-travel health practices. Raising awareness among Hajj/Umrah pilgrims about the importance of seeking professional pre-travel health advice and communicating the risk of exposure to travel-related diseases to pilgrims could be important strategies to improve the uptake of preventive measures. Training of general practitioners in the public health sector about the travel health information would promote the travel health services. Copyright © 2018. Published by Elsevier Ltd.

  6. Analysis of pilgrim dark energy models

    Energy Technology Data Exchange (ETDEWEB)

    Sharif, M.; Jawad, Abdul [University of the Punjab, Department of Mathematics, Lahore (Pakistan)

    2013-04-15

    The proposal of pilgrim dark energy is based on the idea that phantom dark energy possesses enough resistive force to preclude black hole formation. We work on this proposal by choosing an interacting framework with cold dark matter and three cutoffs such as Hubble as well as event horizon and conformal age of the universe. We present a graphical analysis and focus our study on the pilgrim dark energy as well as interacting parameters. It is found that these parameters play an effective role on the equation of state parameter for exploring the phantom region of the universe. We also make the analysis of {omega}-{omega}' and point out freezing region in the {omega}-{omega}' plane. Finally, it turns out that the {Lambda}CDM is achieved in the statefinders plane for all models. (orig.)

  7. High Pressure Coolant Injection (HPCI) system risk-based inspection guide: Pilgrim Nuclear Power Station

    International Nuclear Information System (INIS)

    Shier, W.; Gunther, W.

    1992-10-01

    A review of the operating experience for the High Pressure Coolant Injection (HPCI) system at the Pilgrim Nuclear Power Station is described in this report. The information for this review was obtained from Pilgrim Licensee Event Reports (LERs) that were generated between 1980 and 1989. These LERs have been categorized into 23 failure modes that have been prioritized based on probabilistic risk assessment considerations. In addition, the results of the Pilgrim operating experience review have been compared with the results of of a similar, industry wide operating experience review. this comparison provides an indication of areas in the Pilgrim HPCI system that should be given increased attention in the prioritization of inspection resources

  8. An historical ophthalmic study of Jane Austen.

    Science.gov (United States)

    Wilson, Graham A

    2012-11-01

    Today, no other classic novelist has the popularity or power of Jane Austen, and in 2013 the world will celebrate 200 years of her comic masterpiece Pride and Prejudice. Her millions of fans have an abiding fascination with all aspects of her life, including her health and the cause of her death. This historical ophthalmic study of Jane Austen, based on very incomplete medical bibliographic data, finds that she had a mild ocular surface disorder from age 23. This disorder did not significantly impact on her visual performance for writing. There are many references to eyes in her novels, but Jane's eyes and those of her characters cannot contribute further to the debate around the cause of her death at age 41.

  9. Expression Pattern and Localization Dynamics of Guanine Nucleotide Exchange Factor RIC8 during Mouse Oogenesis.

    Directory of Open Access Journals (Sweden)

    Merly Saare

    Full Text Available Targeting of G proteins to the cell cortex and their activation is one of the triggers of both asymmetric and symmetric cell division. Resistance to inhibitors of cholinesterase 8 (RIC8, a guanine nucleotide exchange factor, activates a certain subgroup of G protein α-subunits in a receptor independent manner. RIC8 controls the asymmetric cell division in Caenorhabditis elegans and Drosophila melanogaster, and symmetric cell division in cultured mammalian cells, where it regulates the mitotic spindle orientation. Although intensely studied in mitosis, the function of RIC8 in mammalian meiosis has remained unknown. Here we demonstrate that the expression and subcellular localization of RIC8 changes profoundly during mouse oogenesis. Immunofluorescence studies revealed that RIC8 expression is dependent on oocyte growth and cell cycle phase. During oocyte growth, RIC8 is abundantly present in cytoplasm of oocytes at primordial, primary and secondary preantral follicle stages. Later, upon oocyte maturation RIC8 also populates the germinal vesicle, its localization becomes cell cycle dependent, and it associates with chromatin and the meiotic spindle. After fertilization, RIC8 protein converges to the pronuclei and is also detectable at high levels in the nucleolus precursor bodies of both maternal and paternal pronucleus. During first cleavage of zygote RIC8 localizes in the mitotic spindle and cell cortex of forming blastomeres. In addition, we demonstrate that RIC8 co-localizes with its interaction partners Gαi1/2:GDP and LGN in meiotic/mitotic spindle, cell cortex and polar bodies of maturing oocytes and zygotes. Downregulation of Ric8 by siRNA leads to interferred translocation of Gαi1/2 to cortical region of maturing oocytes and reduction of its levels. RIC8 is also expressed at high level in female reproductive organs e.g. oviduct. Therefore we suggest a regulatory function for RIC8 in mammalian gametogenesis and fertility.

  10. Management of heatstroke in Malaysian pilgrims in Saudi Arabia.

    Science.gov (United States)

    Merican, M I

    1989-09-01

    Heat stroke is hardly seen in Malaysia. However, it occurs commonly in Saudi Arabia during the Haj season. Many Malaysian pilgrims are affected every year and some die. Having faced this environmental hazard for eight years, the Malaysian Medical Mission, sent each year to look after our pilgrims, modified its treatment strategy in 1988 and successfully decreased the overall morbidity and mortality of affected patients without the use of sophisticated equipment. A brief account of the management of 17 cases seen in 1988 is given. Only one died following treatment. The rest recovered fully without any residual neurological deficit or other complications.

  11. A ROP2-RIC1 pathway fine-tunes microtubule reorganization for salt tolerance in Arabidopsis.

    Science.gov (United States)

    Li, Changjiang; Lu, Hanmei; Li, Wei; Yuan, Ming; Fu, Ying

    2017-07-01

    The reorganization of microtubules induced by salt stress is required for Arabidopsis survival under high salinity conditions. RIC1 is an effector of Rho-related GTPase from plants (ROPs) and a known microtubule-associated protein. In this study, we demonstrated that RIC1 expression decreased with long-term NaCl treatment, and ric1-1 seedlings exhibited a higher survival rate under salt stress. We found that RIC1 reduced the frequency of microtubule transition from shortening to growing status and knockout of RIC1 improved the reassembly of depolymerized microtubules caused by either oryzalin treatment or salt stress. Further investigation showed that constitutively active ROP2 promoted the reassembly of microtubules and the survival of seedlings under salt stress. A rop2-1 ric1-1 double mutant rescued the salt-sensitive phenotype of rop2-1, indicating that ROP2 functions in salt tolerance through RIC1. Although ROP2 did not regulate RIC1 expression upon salt stress, a quick but mild increase of ROP2 activity was induced, led to reduction of RIC1 on microtubules. Collectively, our study reveals an ROP2-RIC1 pathway that fine-tunes microtubule dynamics in response to salt stress in Arabidopsis. This finding not only reveals a new regulatory mechanism for microtubule reorganization under salt stress but also the importance of ROP signalling for salinity tolerance. © 2017 John Wiley & Sons Ltd.

  12. Causes of Mortality for Indonesian Hajj Pilgrims: Comparison between Routine Death Certificate and Verbal Autopsy Findings

    Science.gov (United States)

    Pane, Masdalina; Imari, Sholah; Alwi, Qomariah; Nyoman Kandun, I; Cook, Alex R.; Samaan, Gina

    2013-01-01

    Background Indonesia provides the largest single source of pilgrims for the Hajj (10%). In the last two decades, mortality rates for Indonesian pilgrims ranged between 200–380 deaths per 100,000 pilgrims over the 10-week Hajj period. Reasons for high mortality are not well understood. In 2008, verbal autopsy was introduced to complement routine death certificates to explore cause of death diagnoses. This study presents the patterns and causes of death for Indonesian pilgrims, and compares routine death certificates to verbal autopsy findings. Methods Public health surveillance was conducted by Indonesian public health authorities accompanying pilgrims to Saudi Arabia, with daily reporting of hospitalizations and deaths. Surveillance data from 2008 were analyzed for timing, geographic location and site of death. Percentages for each cause of death category from death certificates were compared to that from verbal autopsy. Results In 2008, 206,831 Indonesian undertook the Hajj. There were 446 deaths, equivalent to 1,968 deaths per 100,000 pilgrim years. Most pilgrims died in Mecca (68%) and Medinah (24%). There was no statistically discernible difference in the total mortality risk for the two pilgrimage routes (Mecca or Medinah first), but the number of deaths peaked earlier for those traveling to Mecca first (p=0.002). Most deaths were due to cardiovascular (66%) and respiratory (28%) diseases. A greater proportion of deaths were attributed to cardiovascular disease by death certificate compared to the verbal autopsy method (pIndonesian pilgrim mortality rates were very high. Correct classification of cause of death is critical for the development of risk mitigation strategies. Since verbal autopsy classified causes of death differently to death certificates, further studies are needed to assess the method’s utility in this setting. PMID:23991182

  13. 26 CFR 1.852-12 - Non-RIC earnings and profits.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Non-RIC earnings and profits. 1.852-12 Section 1.852-12 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Regulated Investment Companies and Real Estate Investment Trusts § 1.852-12 Non-RIC...

  14. Respiratory Viruses and Bacteria among Pilgrims during the 2013 Hajj

    Science.gov (United States)

    Benkouiten, Samir; Charrel, Rémi; Belhouchat, Khadidja; Drali, Tassadit; Nougairede, Antoine; Salez, Nicolas; Memish, Ziad A.; al Masri, Malak; Fournier, Pierre-Edouard; Raoult, Didier; Brouqui, Philippe; Parola, Philippe

    2014-01-01

    Pilgrims returning from the Hajj might contribute to international spreading of respiratory pathogens. Nasal and throat swab specimens were obtained from 129 pilgrims in 2013 before they departed from France and before they left Saudi Arabia, and tested by PCR for respiratory viruses and bacteria. Overall, 21.5% and 38.8% of pre-Hajj and post-Hajj specimens, respectively, were positive for ≥1 virus (p = 0.003). One third (29.8%) of the participants acquired ≥1 virus, particularly rhinovirus (14.0%), coronavirus E229 (12.4%), and influenza A(H3N2) virus (6.2%) while in Saudi Arabia. None of the participants were positive for the Middle East respiratory syndrome coronavirus. In addition, 50.0% and 62.0% of pre-Hajj and post-Hajj specimens, respectively, were positive for Streptococcus pneumoniae (p = 0.053). One third (36.3%) of the participants had acquired S. pneumoniae during their stay. Our results confirm high acquisition rates of rhinovirus and S. pneumoniae in pilgrims and highlight the acquisition of coronavirus E229. PMID:25341199

  15. 33 CFR 165.115 - Safety and Security Zones; Pilgrim Nuclear Power Plant, Plymouth, Massachusetts.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Safety and Security Zones; Pilgrim Nuclear Power Plant, Plymouth, Massachusetts. 165.115 Section 165.115 Navigation and Navigable... Coast Guard District § 165.115 Safety and Security Zones; Pilgrim Nuclear Power Plant, Plymouth...

  16. Father Figures in the Novels of Jane Austen

    Science.gov (United States)

    Odeh, Adli

    2011-01-01

    Miniaturist as Jane Austen is, she has depicted the life of a few families. In her letter to her niece, Anna Austen, she writes: "three or four families in a country village is the very thing to work on"(Chapman's Edition, 1970, P.10). Jane's knowledge about these families is, in no way shallow. It is rich in variation and contrasts.…

  17. Ric-8A, a Gα protein guanine nucleotide exchange factor potentiates taste receptor signaling

    Directory of Open Access Journals (Sweden)

    Claire J Fenech

    2009-10-01

    Full Text Available Taste receptors for sweet, bitter and umami tastants are G-protein coupled receptors (GPCRs. While much effort has been devoted to understanding G-protein-receptor interactions and identifying the components of the signalling cascade downstream of these receptors, at the level of the G-protein the modulation of receptor signal transduction remains relatively unexplored. In this regard a taste-specific regulator of G-protein signaling (RGS, RGS21, has recently been identified. To study whether guanine nucleotide exchange factors (GEFs are involved in the transduction of the signal downstream of the taste GPCRs we investigated the expression of Ric-8A and Ric-8B in mouse taste cells and their interaction with G-protein subunits found in taste buds. Mammalian Ric-8 proteins were initially identified as potent GEFs for a range of Gα subunits and Ric-8B has recently been shown to amplify olfactory signal transduction. We find that both Ric-8A and Ric-8B are expressed in a large portion of taste bud cells and that most of these cells contain IP3R-3 a marker for sweet, umami and bitter taste receptor cells. Ric-8A interacts with Gα-gustducin and Gαi2 through which it amplifies the signal transduction of hTas2R16, a receptor for bitter compounds. Overall, these findings are consistent with a role for Ric-8 in mammalian taste signal transduction.

  18. 8 Pin RIC Socket for Hearing Aid Applications

    DEFF Research Database (Denmark)

    Islam, Aminul; Hansen, Hans Nørgaard; Davids, Søren

    2012-01-01

    process and the other one is fully automated process. This paper presents the entire process chain for both the concepts and makes a comparative analysis based on the experimental investigation and validation. The work presented here can be a source of valuable information for industrial users...... of them. 8 Pin RIC Socket is a functionally versatile product which can combine many different functions and presents many advantages compared with the previous 3 Pin RIC Socket. For the demonstrator production of the new Socket, two different production concepts were chosen- one based on semi-automated...

  19. No MERS-CoV but positive influenza viruses in returning Hajj pilgrims, China, 2013–2015

    Directory of Open Access Journals (Sweden)

    Xuezheng Ma

    2017-11-01

    Full Text Available Abstract Background There is global health concern that the mass movement of pilgrims to and from Mecca annually could contribute to the international spread of Middle East Respiratory Syndrome Coronavirus (MERS-CoV. In China, about 11,000 Muslim pilgrims participate in the Hajj gathering in Mecca annually. This is the first report of MERS-CoV and respiratory virus molecular screening of returning pilgrims at points of entry in China from 2013 to 2015. Methods and results A total of 847 returning Hajj pilgrims participated in this study. The test results indicated that of the travelers, 34 tested positive for influenza A virus, 14 for influenza B virus, 4 for metapneumo virus, 2 for respiratory syncytial virus, and 3 for human coronavirus. There was a significant difference in the rates of positive and negative influenza virus tests between Hajj pilgrims with symptoms and those without. The detection rates of influenza virus were not significantly different among the three years studied, at 5.3, 6.0 and 6.3% for 2013, 2014 and 2015, respectively. Discussion and conclusion The MERS-CoV and respiratory viruses detection results at points of entry in China from 2013 to 2015 indicated that there were no MERS-CoV infection but a 5.7% positive influenza viruses in returning Chinese pilgrims.

  20. Screening Jane. When History, Biography and Fiction create a Cinematic Life.

    Directory of Open Access Journals (Sweden)

    Roberta Grandi

    2015-07-01

    Full Text Available This paper analyzes the interesting technique of adaptation of the film Becoming Jane, a biopic on the life of Jane Austen, released in 2007. Loosely based on Jon Spence's biography Becoming Jane Austen, the film faces the problem of the scarcity of information on Jane Austen's life through a technique that, if not original nor always satisfying, is nevertheless worth being studied. By recurring to the character descriptions and the anecdotes narrated in the novels, the film (and Spence's book too "fills in the blanks" in Austen's life by adding touches of romance with questionable historical accuracy and fictionalizes the writer's biography in order to adapt it to the stereotype of modern romantic film heroines.

  1. Jane: a new tool for the cophylogeny reconstruction problem.

    Science.gov (United States)

    Conow, Chris; Fielder, Daniel; Ovadia, Yaniv; Libeskind-Hadas, Ran

    2010-02-03

    This paper describes the theory and implementation of a new software tool, called Jane, for the study of historical associations. This problem arises in parasitology (associations of hosts and parasites), molecular systematics (associations of orderings and genes), and biogeography (associations of regions and orderings). The underlying problem is that of reconciling pairs of trees subject to biologically plausible events and costs associated with these events. Existing software tools for this problem have strengths and limitations, and the new Jane tool described here provides functionality that complements existing tools. The Jane software tool uses a polynomial time dynamic programming algorithm in conjunction with a genetic algorithm to find very good, and often optimal, solutions even for relatively large pairs of trees. The tool allows the user to provide rich timing information on both the host and parasite trees. In addition the user can limit host switch distance and specify multiple host switch costs by specifying regions in the host tree and costs for host switches between pairs of regions. Jane also provides a graphical user interface that allows the user to interactively experiment with modifications to the solutions found by the program. Jane is shown to be a useful tool for cophylogenetic reconstruction. Its functionality complements existing tools and it is therefore likely to be of use to researchers in the areas of parasitology, molecular systematics, and biogeography.

  2. Jane Austen and Addison's disease: an unconvincing diagnosis.

    Science.gov (United States)

    White, K G

    2009-12-01

    Jane Austen's letters describe a two-year deterioration into bed-ridden exhaustion, with unusual colouring, bilious attacks and rheumatic pains. In 1964, Zachary Cope postulated tubercular Addison's to explain her symptoms and her relatively pain-free illness. Literary scholars later countered this posthumous diagnosis on grounds that are not well substantiated, while medical authors supported his conclusion. Important symptoms reported by contemporary Addison's patients-mental confusion, generalised pain and suffering, weight loss and anorexia-are absent from Jane Austen's letters. Thus, by listening to the patient's perspective, we can conclude it is unlikely that Addison's disease caused Jane Austen's demise. Disseminated bovine tuberculosis would offer a coherent explanation for her symptoms, so that Cope's original suggestion of infective tuberculosis as the cause of her illness may have been correct.

  3. Walking Meditation: Being Present and Being Pilgrim on the Camino de Santiago

    OpenAIRE

    Alison T. Smith

    2018-01-01

    The Camino de Santiago has witnessed an unprecedented number of walkers in recent years. Traditionalists feel that the Camino is suffering from excess—too many visitors and too much strain on the infrastructure, accompanied by an ignorance of what it means to be an “authentic” pilgrim. Contemporary pilgrims often use ancillary services to transport their bags, approaching the Camino as an athletic event or a holiday excursion. For scholars and people of faith, these superficial attitudes to t...

  4. Jane: a new tool for the cophylogeny reconstruction problem

    Directory of Open Access Journals (Sweden)

    Ovadia Yaniv

    2010-02-01

    Full Text Available Abstract Background This paper describes the theory and implementation of a new software tool, called Jane, for the study of historical associations. This problem arises in parasitology (associations of hosts and parasites, molecular systematics (associations of orderings and genes, and biogeography (associations of regions and orderings. The underlying problem is that of reconciling pairs of trees subject to biologically plausible events and costs associated with these events. Existing software tools for this problem have strengths and limitations, and the new Jane tool described here provides functionality that complements existing tools. Results The Jane software tool uses a polynomial time dynamic programming algorithm in conjunction with a genetic algorithm to find very good, and often optimal, solutions even for relatively large pairs of trees. The tool allows the user to provide rich timing information on both the host and parasite trees. In addition the user can limit host switch distance and specify multiple host switch costs by specifying regions in the host tree and costs for host switches between pairs of regions. Jane also provides a graphical user interface that allows the user to interactively experiment with modifications to the solutions found by the program. Conclusions Jane is shown to be a useful tool for cophylogenetic reconstruction. Its functionality complements existing tools and it is therefore likely to be of use to researchers in the areas of parasitology, molecular systematics, and biogeography.

  5. PX-RICS-deficient mice mimic autism spectrum disorder in Jacobsen syndrome through impaired GABAA receptor trafficking.

    Science.gov (United States)

    Nakamura, Tsutomu; Arima-Yoshida, Fumiko; Sakaue, Fumika; Nasu-Nishimura, Yukiko; Takeda, Yasuko; Matsuura, Ken; Akshoomoff, Natacha; Mattson, Sarah N; Grossfeld, Paul D; Manabe, Toshiya; Akiyama, Tetsu

    2016-03-16

    Jacobsen syndrome (JBS) is a rare congenital disorder caused by a terminal deletion of the long arm of chromosome 11. A subset of patients exhibit social behavioural problems that meet the diagnostic criteria for autism spectrum disorder (ASD); however, the underlying molecular pathogenesis remains poorly understood. PX-RICS is located in the chromosomal region commonly deleted in JBS patients with autistic-like behaviour. Here we report that PX-RICS-deficient mice exhibit ASD-like social behaviours and ASD-related comorbidities. PX-RICS-deficient neurons show reduced surface γ-aminobutyric acid type A receptor (GABAAR) levels and impaired GABAAR-mediated synaptic transmission. PX-RICS, GABARAP and 14-3-3ζ/θ form an adaptor complex that interconnects GABAAR and dynein/dynactin, thereby facilitating GABAAR surface expression. ASD-like behavioural abnormalities in PX-RICS-deficient mice are ameliorated by enhancing inhibitory synaptic transmission with a GABAAR agonist. Our findings demonstrate a critical role of PX-RICS in cognition and suggest a causal link between PX-RICS deletion and ASD-like behaviour in JBS patients.

  6. Ablation of RIC8A function in mouse neurons leads to a severe neuromuscular phenotype and postnatal death.

    Directory of Open Access Journals (Sweden)

    Katrin Ruisu

    Full Text Available Resistance to inhibitors of cholinesterase 8 (RIC8 is a guanine nucleotide exchange factor required for the intracellular regulation of G protein signalling. RIC8 activates different Gα subunits via non-canonical pathway, thereby amplifying and prolonging the G protein mediated signal. In order to circumvent the embryonic lethality associated with the absence of RIC8A and to study its role in the nervous system, we constructed Ric8a conditional knockout mice using Cre/loxP technology. Introduction of a synapsin I promoter driven Cre transgenic mouse strain (SynCre into the floxed Ric8a (Ric8a (F/F background ablated RIC8A function in most differentiated neuron populations. Mutant SynCre (+/- Ric8 (lacZ/F mice were born at expected Mendelian ratio, but they died in early postnatal age (P4-P6. The mutants exhibited major developmental defects, like growth retardation and muscular weakness, impaired coordination and balance, muscular spasms and abnormal heart beat. Histological analysis revealed that the deficiency of RIC8A in neurons caused skeletal muscle atrophy and heart muscle hypoplasia, in addition, the sinoatrial node was misplaced and its size reduced. However, we did not observe gross morphological changes in brains of SynCre (+/- Ric8a (lacZ/F mutants. Our results demonstrate that in mice the activity of RIC8A in neurons is essential for survival and its deficiency causes a severe neuromuscular phenotype.

  7. Ablation of RIC8A function in mouse neurons leads to a severe neuromuscular phenotype and postnatal death.

    Science.gov (United States)

    Ruisu, Katrin; Kask, Keiu; Meier, Riho; Saare, Merly; Raid, Raivo; Veraksitš, Alar; Karis, Alar; Tõnissoo, Tambet; Pooga, Margus

    2013-01-01

    Resistance to inhibitors of cholinesterase 8 (RIC8) is a guanine nucleotide exchange factor required for the intracellular regulation of G protein signalling. RIC8 activates different Gα subunits via non-canonical pathway, thereby amplifying and prolonging the G protein mediated signal. In order to circumvent the embryonic lethality associated with the absence of RIC8A and to study its role in the nervous system, we constructed Ric8a conditional knockout mice using Cre/loxP technology. Introduction of a synapsin I promoter driven Cre transgenic mouse strain (SynCre) into the floxed Ric8a (Ric8a (F/F) ) background ablated RIC8A function in most differentiated neuron populations. Mutant SynCre (+/-) Ric8 (lacZ/F) mice were born at expected Mendelian ratio, but they died in early postnatal age (P4-P6). The mutants exhibited major developmental defects, like growth retardation and muscular weakness, impaired coordination and balance, muscular spasms and abnormal heart beat. Histological analysis revealed that the deficiency of RIC8A in neurons caused skeletal muscle atrophy and heart muscle hypoplasia, in addition, the sinoatrial node was misplaced and its size reduced. However, we did not observe gross morphological changes in brains of SynCre (+/-) Ric8a (lacZ/F) mutants. Our results demonstrate that in mice the activity of RIC8A in neurons is essential for survival and its deficiency causes a severe neuromuscular phenotype.

  8. La philosophie ricœurienne de l’esthétique entre poétique et éthique

    Directory of Open Access Journals (Sweden)

    Samuel Lelièvre

    2017-02-01

    Full Text Available Ricœur’s philosophy never locates itself directly in the field of philosophical aesthetics inasmuch as philosophical aesthetics never arises as a field of major questioning and discursive development for Ricœur’s philosophy or as a field that would guide that philosophy. However, Ricœur maintains an ongoing but complex connection with aesthetics throughout his philosophical work. Here we defend the thesis that there are difficulties relating both to the complexity of Ricœur’s philosophy and to the crisis situation of aesthetics as an autonomous field of philosophical inquiry. A more direct confrontation with philosophical aesthetics, such as that developed by analytic philosophy and critical theory today, is necessary in order to be aware of this connection between Ricœur’s philosophy and aesthetics. It then appears that if Ricœur’s philosophy makes it possible to maintain a certain autonomy of the field of aesthetics inherited from Kant, it is not through developing some unlikely “Ricœurian aesthetic” but thanks to a Ricœurian philosophy of aesthetics essentially determined on three levels: 1 the connection between poetics and aesthetics within a philosophy of imagination, 2 the connection between criticism and hermeneutics with regard the notions of text and distanciation, 3 the connection between ontology and communication that summarizes the two previous steps by combining phenomenological, analytic and critical perspectives. Thus it can be assumed that this autonomy of the field of aesthetics is possible only at a horizon of meaning determined by Ricœur’s philosophical anthropology: at the axiological level, the field of aesthetics differs upstream from the field of poetics and downstream from the field of ethics; at the ontological level, Ricœur’s philosophy of aesthetics concerns a region that is both intermediate between and congruent to those treated by Ricœur’s philosophy of imagination and by Ric

  9. Exploring resident-empowered meetingplaces in Dutch neighbourhoods : by Jane Jacobs Walking Action-research methodology

    NARCIS (Netherlands)

    Sanders, F.C.

    2016-01-01

    The ‘Jane Jacobs Walk’ organization as one of the Jane Jacobs (1916-2006) heritage initiative supported three Jane Jacobs Walks of certified Fred Sanders in the period 2011 - 2014 in Amsterdam neighbourhoods. These walks helped residents to explore resident-empowered meeting-places and activities in

  10. The analogic model ''RIC'' of thermal behaviour of mass concrete

    International Nuclear Information System (INIS)

    Gonzalez Redondo, M.; Gonzalez de Posada, F.; Plana Claver, J.

    1997-01-01

    In order to study the thermal field and calorific flows in heat sources (i.e. mass concrete during setting) we have conceived, built and experimented with an analogical electric model. This model, named RIC, consists of resistors (R) and capacitors (C) in which nodes an electric current (I) has been injected. Several analogical constants were used for the mathematical approximation. Thus, this paper describes the analogical RIC model, simulating heat generation, boundary and initial conditions and concreting. (Author) 4 refs

  11. Clumsy City by Design : A Theory for Jane Jacobs’ Imperfect Cities?

    NARCIS (Netherlands)

    Schmitt, Sarah-Maria; Hartmann, T.|info:eu-repo/dai/nl/343441349

    2016-01-01

    How do different concepts of justice correspond with the principles of diversity in cities introduced by Jane Jacobs? This contribution connects Jane Jacobs’ ideas on the diverse city with Mary Douglas’ Cultural Theory and its concept of clumsy solutions. According to Douglas’ Cultural Theory, every

  12. Arendt and Ricœur on Ideology and Authority.

    Directory of Open Access Journals (Sweden)

    Carlos Alfonso Garduño Comparán

    2014-12-01

    Full Text Available AbstractHannah Arendt’s work is an important reference for Paul Ricœur. Her definition of power as the free action in concert of individuals within a community of equals, guaranteed by institutions, allows Ricœur to ground his reflection on the political dimension of recognition and justice. However, as I will show in this paper, such a definition is problematic, particularly because of the relation that Arendt establishes between power and authority, her decision to separate the social and the political, and her understanding of ideology, philosophy, and common sense in politics.After describing Arendt’s account of the relation between power and authority, I argue that, without rejecting the spirit of her political thought or her basic concepts, Ricœur’s reflections on the functions of ideology in his Lectures on Ideology and Utopia offer a broader but complementary vision that allows us to understand the issues that remain obscure in Arendt’s approach.Keywords: Arendt, Ideology, Authority, Power, Social.RésuméL’œuvre de Hannah Arendt constitue une référence importante pour Paul Ricœur. La définition arendtienne du pouvoir comme agir ensemble des individus au sein d’une communauté d’égaux garantie par des institutions, fournit en effet à Ricœur les bases de sa réflexion sur la dimension politique de la reconnaissance et de la justice. Cependant, cet article s’efforce de montrer qu’une telle définition est problématique, non seulement en raison de la relation qu’Arendt établit entre le pouvoir et l’autorité, mais aussi en ce qui concerne sa distinction du social et du politique, sa compréhension de l’idéologie, ainsi que sa conception de la philosophie et du sens commun dans le domaine politique.Après une analyse des thèses d’Arendt sur la relation entre le pouvoir et l’autorité, cet article soutient que, sans rejeter l’esprit de la pensée politique arendtienne et ses concepts de base, la

  13. Jane Eyre fait de la résistance

    OpenAIRE

    Bazin, Claire

    2015-01-01

    “Speak I must; I had been trodden on severely and must turn”. It is with these unspoken but no less eloquent words that Jane starts attacking her baffled aunt, who is not used to being addressed in this way by one who is usually obedient and silent. The scene, which follows the incarceration in the red room and Brocklehurst’s visit, can be read as a "Vindication of the rights of Jane” and also as both a metamorphosis and a reversal: Jane is out of herself and rebels against the enemy who grad...

  14. Jane Austen's (1775-1817) references to headache: fact and fiction.

    Science.gov (United States)

    Larner, A J

    2010-11-01

    References to headache in Jane Austen's works, both fictional and non-fictional, and in biographical works undertaken by Austen family members have been collated. These multiple references suggest that Jane Austen used headache as a narrative device to reflect not only physiological bodily processes but also psychological states, possibly based on her own experience of headache and that of female relations and acquaintances.

  15. Pilgrim or Tourist? : Modelling Two Types of Travel Bloggers

    NARCIS (Netherlands)

    van Nuenen, Tom; van der Beek, Suzanne

    2016-01-01

    The typological distinction between pilgrims and tourists has often been drawn in tourism studies. This article aims at complementing this debate by applying computational techniques to analyse discourses in a corpus of blogs from the Dutch travel blog repository of waarbenjij.nu. The hypothesis is

  16. In Memoriam Éric Thomé (1976-2015)

    OpenAIRE

    2016-01-01

    Éric Thomé, trente‑neuf ans, graphiste et photographe, est décédé lors des attentats du 13 novembre 2015. Il se trouvait au Bataclan. Diplômé d’un BTS communication visuel au lycée de Sèvres, il avait travaillé pendant huit ans comme directeur artistique dans la publicité. Il avait par la suite cofondé le studio de design graphique We Are Ted à Paris avec Laurent Duvoux. C’est dans ce cadre qu’Éric avait contribué à créer la maquette de la revue Sociologie. La déclinaison d’un logo dans plusi...

  17. La conception ricœurienne de la raison pratique: Dialectique ou éclectique?

    Directory of Open Access Journals (Sweden)

    Laurent Jaffro

    2012-06-01

    Full Text Available This article examines and discusses the presuppositions behind the answer that Paul Ricœur brought to the question “What is practical reason?” in a series of studies that led to the “little ethics” of Oneself as Another.  The conception defended by Ricœur is presented as a sort of reconciliation, or composition, of Aristotelian ethics and Kantian morality. Two problems in particular are raised: the first is raised by the questionable nature of Ricœur’s interpretation of the positions that he synthesizes; the second concerns the model - dialectic or eclectic – of this synthesis.

  18. Pilgrim dark energy with apparent and event horizons in non-flat universe

    International Nuclear Information System (INIS)

    Sharif, M.; Jawad, Abdul

    2013-01-01

    Pilgrim dark energy is an interesting proposal which is based on the conjecture that phantom-like dark energy with strong enough repulsive force can prevent the formation of a black hole. We investigate this conjecture by assuming the apparent and event horizons in non-flat universe and we develop different cosmological parameters. We construct the corresponding equation of state parameter, which indicates that its present values lie in the phantom era of the universe for different ranges of μ (pilgrim dark energy parameter) as well as ξ 2 (interacting parameter). It is interesting to mention here that the pilgrim dark energy with event horizon yields a phantom region for all cases of ξ 2 with μ Λ - ω' Λ plane and explore the thawing as well as freezing region and ΛCDM limit for these models. The statefinders plane is also constructed, which shows the correspondence with different models such as quintessence and phantom dark energy, ΛCDM and Chaplygin gas. Finally, we investigate the validity of the generalized second law of thermodynamics with event horizon in a flat as well as non-flat universe. (orig.)

  19. Mobilizing coastal resources along a digitally facilitated pilgrim trail

    DEFF Research Database (Denmark)

    Meged, Jane Widtfeldt; Gyimóthy, Szilvia

    The recently opened pilgrim trail, Camønoen represents an adapted collaborative business model and as such an appropriate case to study new coastal value creation processes. Our paper will follow the consolidation of Camønoen by analyzing its business model, the institutionalisation of brokers...

  20. Facebook històric

    OpenAIRE

    Valverde Galceran, Eva

    2018-01-01

    El projecte Facebook històric, pretén ser un aplicatiu web amb l'objectiu principal de mostrar d'una manera intuïtiva i gràfica tota la informació que s'ha obtingut fins al moment dels nostres avantpassats. També serà un aplicatiu que permetrà a qualsevol persona poder fer una publicació (text, fotografia, vídeo, document digital·litzat, etc), per així poder anar construint d'alguna manera el lifelogging dels nostres avantpassats i saber la manera en com estaven relacionats uns avantpassats a...

  1. Rapid Inventory Collection System (RICS) and the 2009 Victorian Bushfires impact assessment

    Energy Technology Data Exchange (ETDEWEB)

    Habili, N; Corby, N; Cechet, R P, E-mail: nariman.habili@ga.gov.a [Risk and Impact Analysis Group, Geoscience Australia G.PO Box 378, Canberra, Australian Capital Territory (Australia)

    2010-08-15

    The Rapid Inventory Collection System (RICS) is a vehicular data collection system (image and GPS) used for building/infrastructure damage and inventory assessment. The system consists of Ethernet cameras attached to a tripod mounted on a motor vehicle, a GPS receiver and software written in C++. RICS was deployed following the 2009 Victorian Bushfires and the collected data was used by the Victorian Bushfires Royal Commission for the impact assessment (field survey) which quantified the extent and severity of the damage caused to residential buildings by the fire-storm. The regions of Kilmore East, Murrindindi, Churchill, Maiden Gully - Bendigo and Bunyip had nearly 5400 residential structures within the fire perimeter. Analysis utilising both aerial and vehicular (RICS) imagery indicates that just over 2100 homes were destroyed and an additional 800 received minor damage.

  2. "A transcript of actual life": headache in the novels of Jane Austen.

    Science.gov (United States)

    Larner, Andrew J

    2010-04-01

    References to headache in the novels of Jane Austen have been examined. Nine characters, all female, suffer headache at one time or another, often in association with emotionally stressful situations. As an authorial device, headache may have served Jane Austen as a culturally sanctioned form of bodily expression.

  3. Was Jane Addams a Promiscuous Pragmatist?

    Science.gov (United States)

    Atkinson, Becky

    2013-01-01

    Contemporary pragmatist and feminist scholars have proposed the possibilities for "changing the theoretical analyses and concrete practices" of both feminism and classical American pragmatism offered by its recuperation through feminism. Particularly, scholarship on Jane Addams has reached back to retrieve her activism, ethics, and…

  4. Pilgrim Souvenir: Ampulla of Thomas Becket

    OpenAIRE

    Amy Jeffs

    2017-01-01

    This tin ampulla was probably purchased by a pilgrim near the shrine of St Thomas Becket in Canterbury. It is designed to contain holy water and be hung around the neck on a cord. Measuring 100 by 87 millimetres, it is in the form of a narrow, pointed vessel surrounded by an openwork penannular frame and would have been rapidly slush-cast, in one go, in a three-part mould. A date in the first half of the thirteenth century is probable based on the style of the military figures’ armour and the...

  5. Identification of critical amino acids in the IgE epitopes of Ric c 1 and Ric c 3 and the application of glutamic acid as an IgE blocker.

    Science.gov (United States)

    Deus-de-Oliveira, Natalia; Felix, Shayany P; Carrielo-Gama, Camila; Fernandes, Keysson V; DaMatta, Renato Augusto; Machado, Olga L T

    2011-01-01

    The allergenicity of Ricinus communis L. (castor bean, Euphorbiaceae) is associated with components of its seeds and pollen. Castor bean allergy has been described not only in laboratory workers, but also in personnel working in oil processing mills, fertilizer retail, the upholstery industry and other industrial fields. In the present study, we describe the critical amino acids in the IgE-binding epitopes in Ric c 1 and Ric c 3, two major allergens of R. communis. In addition, we also investigate the cross-reactivity between castor bean and some air and food allergen extracts commonly used in allergy diagnosis. The IgE reactivity of human sera from atopic patients was screened by immune-dot blot against castor bean allergens. Allergenic activity was evaluated in vitro using a rat mast cell activation assay and by ELISA. Cross-reactivity was observed between castor bean allergens and extracts from shrimp, fish, gluten, wheat, soybean, peanut, corn, house dust, tobacco and airborne fungal allergens. We observed that treatment of rat and human sera (from atopic patients) with glutamic acid reduced the IgE-epitope interaction. The identification of glutamic acid residues with critical roles in IgE-binding to Ric c 3 and Ric c 1 support the potential use of free amino acids in allergy treatment.

  6. An Comparative Study of Jane Eyre's Fate and Tess's Fate from Femi-nist Viewpoint%An Comparative Study of Jane Eyre's Fate and Tess's Fate from Femi?nist Viewpoint

    Institute of Scientific and Technical Information of China (English)

    陈静; 何泠静

    2017-01-01

    In"Jane Eyre", Charlotte Bronte's masterpiece the heroine, Jane Eyre has fully reflected her self-esteem, equality, and pure personality, which are also reflected in her concept of love vividly. However, Thomas Hardy's Tess is poor and kind, but she does not have a complete love like Jane Eyre, and she is described by his criticism of the old moral character with good vir-tues in the traditional sense. She is a new image of modern feminism who suffered from the old moral sense and gradually has re-volt consciousness. From the feminism viewpoint, this paper attempts to analysis the causes of their different fate from different points and reveal the impact of social background on their fates.

  7. The Manifestations of Military Gender Role Issue on Ridley Scott's G. I. Jane Movie

    OpenAIRE

    PUTRA, ABEDNEGO ANGGA JURIAN

    2015-01-01

    Keywords: gender discrimination, women in military, feminism, G.I. Jane movie. Gender discrimination threats the equality of women's role. One of the causes of gender discrimination is patriarchal system in society. A movie entitled G.I. Jane reveals some causes and manifestations of gender discrimination in military.This research applies Feminism approach to analyze a movie entitled G.I. Jane. This study also applies the concept of gender role, women in military, and film studies.The result ...

  8. High prevalence of common respiratory viruses and no evidence of Middle East respiratory syndrome coronavirus in Hajj pilgrims returning to Ghana, 2013.

    Science.gov (United States)

    Annan, Augustina; Owusu, Michael; Marfo, Kwadwo Sarfo; Larbi, Richard; Sarpong, Francisca Naana; Adu-Sarkodie, Yaw; Amankwa, Joseph; Fiafemetsi, Samuel; Drosten, Christian; Owusu-Dabo, Ellis; Eckerle, Isabella

    2015-06-01

    The Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 on the Arabian Peninsula and has caused severe respiratory disease with more than 800 laboratory-confirmed cases. The return of infected pilgrims to their home countries with a putative spread of MERS-CoV necessitates further surveillance. A cross sectional study of 839 adult African Hajj pilgrims returning to Accra in Ghana, West Africa, was conducted in 2013 to assess the prevalence of respiratory symptoms as well as of MERS-CoV, human rhinovirus (HRV), respiratory syncytial virus (RSV) and influenza A virus (FLU A) infection. Six hundred and fifty-one (77.6%) pilgrims had respiratory symptoms. Tests were positive for at least one of the viruses other than MERS-CoV in 179 (21.3%) of all pilgrims, with 22.4% detection in symptomatic vs. 17.6% detection in asymptomatic pilgrims. No MERS-CoV was detected, although common respiratory viruses were prevalent, with positive findings for HRV in 141 individuals (16.8%), RSV in 43 individuals (5.1%) and FLU A in 11 individuals (1.3%). Results were positive for more than one virus in 16 (1.9%) individuals, including 14 (1.7%) RSV/HRV co-infections and 2 (0.2%) FLU A/HRV co-infections. A total 146 (22.4%) of the symptomatic returnees tested positive for at least one respiratory virus compared with 33 (17.6%) of the asymptomatic pilgrims who had at least one detectable virus in their sample. The prevalence of viral respiratory infections among Hajj pilgrims in both symptomatic and asymptomatic subjects was high. Although it is reassuring that MERS-CoV was not detected in the tested population, there is a need for active surveillance of Hajj pilgrims. © 2015 John Wiley & Sons Ltd.

  9. Channeling Jane Austen: how it helped me become a better psychotherapist.

    Science.gov (United States)

    Carver, Christi R

    2014-08-01

    The influences on a therapist are many. This article illustrates how a 19th-century novelist, Jane Austen, informs the work of a nurse therapist in the 21st century. The characters in a Jane Austen novel provide perspectives from setting boundaries to handling feelings. Austen's characters promote an acceptance of less attractive qualities in others and in oneself that can benefit the therapy. Copyright 2014, SLACK Incorporated.

  10. Identification of critical amino acids in the IgE epitopes of Ric c 1 and Ric c 3 and the application of glutamic acid as an IgE blocker.

    Directory of Open Access Journals (Sweden)

    Natalia Deus-de-Oliveira

    Full Text Available BACKGROUND: The allergenicity of Ricinus communis L. (castor bean, Euphorbiaceae is associated with components of its seeds and pollen. Castor bean allergy has been described not only in laboratory workers, but also in personnel working in oil processing mills, fertilizer retail, the upholstery industry and other industrial fields. In the present study, we describe the critical amino acids in the IgE-binding epitopes in Ric c 1 and Ric c 3, two major allergens of R. communis. In addition, we also investigate the cross-reactivity between castor bean and some air and food allergen extracts commonly used in allergy diagnosis. METHODOLOGY/PRINCIPAL FINDINGS: The IgE reactivity of human sera from atopic patients was screened by immune-dot blot against castor bean allergens. Allergenic activity was evaluated in vitro using a rat mast cell activation assay and by ELISA. Cross-reactivity was observed between castor bean allergens and extracts from shrimp, fish, gluten, wheat, soybean, peanut, corn, house dust, tobacco and airborne fungal allergens. We observed that treatment of rat and human sera (from atopic patients with glutamic acid reduced the IgE-epitope interaction. CONCLUSIONS/SIGNIFICANCE: The identification of glutamic acid residues with critical roles in IgE-binding to Ric c 3 and Ric c 1 support the potential use of free amino acids in allergy treatment.

  11. Pilgrim Souvenir: Ampulla of Thomas Becket

    Directory of Open Access Journals (Sweden)

    Amy Jeffs

    2017-06-01

    Full Text Available This tin ampulla was probably purchased by a pilgrim near the shrine of St Thomas Becket in Canterbury. It is designed to contain holy water and be hung around the neck on a cord. Measuring 100 by 87 millimetres, it is in the form of a narrow, pointed vessel surrounded by an openwork penannular frame and would have been rapidly slush-cast, in one go, in a three-part mould. A date in the first half of the thirteenth century is probable based on the style of the military figures’ armour and the archaeological contexts of stylistically similar ampullae.

  12. The prevalence and preventive measures of the respiratory illness among Malaysian pilgrims in 2013 Hajj season.

    Science.gov (United States)

    Hashim, Suhana; Ayub, Zeti N; Mohamed, Zeehaida; Hasan, Habsah; Harun, Azian; Ismail, Nabilah; Rahman, Zaidah A; Suraiya, Siti; Naing, Nyi Nyi; Aziz, Aniza A

    2016-02-01

    Respiratory illness continues to exert a burden on hajj pilgrims in Makkah. The purpose of this study is to determine the prevalence of respiratory illness and its associated factors among Malaysian hajj pilgrims in 2013 and to describe its preventive measures. A cross-sectional study was conducted in Makkah and Malaysia during the 2013 hajj season. A self-administered proforma on social demographics, previous experience of hajj or umrah, smoking habits, co-morbid illness and practices of preventive measures against respiratory illness were obtained. A total of 468 proforma were analysed. The prevalence of the respiratory illness was 93.4% with a subset of 78.2% fulfilled the criteria for influenza-like illness (ILI). Most of them (77.8%) had a respiratory illness of food supplement. Malaysian hajj pilgrims with previous experience of hajj (OR 0.24; 95% CI 0.10-0.56) or umrah (OR 0.19; 95% CI 0.07-0.52) and those who have practiced good hand hygiene (OR 0.35; 95% CI 0.16-0.79) were found to be significantly associated with lower risk of having respiratory illness. Otherwise, pilgrims who had contact with those with respiratory illness (OR 2.61; 95% CI 1.12-6.09) was associated with higher risk. The prevalence of respiratory illness remains high among Malaysian hajj pilgrims despite having some practices of preventive measures. All preventive measures which include hand hygiene, wearing face masks and influenza vaccination must be practiced together as bundle of care to reduce respiratory illness effectively. © The Author 2016. Published by Oxford University Press on behalf of International society of travel medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  13. Jane Eyre, Past and Present Jane Eyre, d’hier à aujourd’hui

    Directory of Open Access Journals (Sweden)

    Armelle Parey

    2009-10-01

    Full Text Available The present collection of articles along with a few additional contributions contains the proceedings of a conference held at the university of Caen Basse-Normandie, France in May 2004. Entitled “Jane Eyre, Past and Present”, its aim was to study the posterity of Charlotte Brontë’s novel and/or character since its publication in 1847. That two-thirds of the texts studied in this volume were published in the last decade of the twentieth century attests to the fact that rewriting has become a m...

  14. Jane Eyre : un roman innovant pour les critiques victoriens Jane Eyre: an Innovating Novel according to the Victorian Critics

    Directory of Open Access Journals (Sweden)

    Odile Boucher-Rivalain

    2009-07-01

    Full Text Available After the failure to publish her first novel The Professor Charlotte Brontë wrote her second work of fiction Jane Eyre in a conscious effort to satisfy the critics’ expectations, combining the more traditional elements of novel-writing with more innovating ones suggested by her own imagination. An examination of the reviews which appeared in the months following the publication of Jane Eyre reveals Charlotte Brontë’s strategy: her choice of an unconventional relationship between the poor, plain governess and her wealthy, passionate master, the exploration of her heroine’s interior life combined with the realistic descriptions of her characters’ physical and social environment. This combination ensured the success of the novel which was overwhelmingly praised for its innovative elements even if the more conservative critics disapproved of such novelties.

  15. The History of Miss Jane Pittman

    Directory of Open Access Journals (Sweden)

    Christopher Mulvey

    2006-05-01

    Full Text Available This paper explores the ways in which Ernest J. Gaines uses fiction in The Autobiography of Miss Jane Pittman to write a history of the African American from 1861 to 1961. The “Introduction” sets the novel going, but its direction has already been given in the unusual dedication to his grandmother, stepfather and aunt “who did not walk a day in her life but who taught me the importance of standing” (Gaines iv. The significance for Gaines is that what happened a hundred years ago is part of his present-day lived life.The nineteenth-century novel was possessed by history, and white nineteenth-century novelists found their great subject in the war of European nations that was fought between 1799 and 1815. But that was not an American war nor was it an African American war. For Gaines, the war that makes the great turning point of a nation and a people is the American Civil War, fought from 1861 to 1865. It resulted in a moment of history after which life would not be the same. However, one of the main points that Gaines makes about that great turning point in history is that everything changed and nothing changed. And his main fictional device to establish that truth is to tell the history of the hundred years since Emancipation as the story of one woman. Her autobiography becomes an ethno-biography.The continuity forwards from 1861 is given through the life of one woman, but Gaines’s uses another device to provide a continuity backwards from 1861. The young man who wants to get Miss Jane Pittman’s story upsets her with his persistence: “What you want know about Miss Jane for?’ Mary said. ‘I teach history,’ I said. ‘I’m sure her life’s story can help me explain things to my students.’ ‘What’s wrong with them books you already got?’ Mary said. ‘Miss Jane is not in them,’ I said” (Gaines v. Ernest J. Gaines wrote at a time when historians finally began to recognize that they could get no true history of the

  16. Peace Pilgrim: A Readers Theatre Approach to Peace Education.

    Science.gov (United States)

    Curran, Joanne M.

    Readers theater is a dramatic art that directs attention to the words of a text. During a performance, a reader (rather than an actor) presents and interprets the work within a narrative context intended by the author. In this project, the text, a collection of the words and writings of a woman known as the Peace Pilgrim, tells the story of her…

  17. On a Comparison and Contrast of Sherlock Holmes And Miss Jane Marple

    Institute of Scientific and Technical Information of China (English)

    张豪若

    2014-01-01

    In the history of detective stories, Sherlock Holmes and Miss Jane Marple remain as two of the most prominent fig-ures. Focusing on the two detectives' images, personality traits, detective strategies as well as settings of the stories, this study ex-amines the grounds that magnetize readers.The purpose of this research is to inquire into readers' orientations to Sherlock Holm-es and Miss Jane Marple, and to investigate the causes for their views. To fulfill that purpose, a questionnaire was designed and dis-tributed. Sherlock Holmes and Miss Jane Marple prove themselves to be successful detectives. Both of them have distinct images and personality traits as well as plausible detective strategies. The settings, combining reality with imagination, also play a dispens-able role. Besides, reasons given by students who disbelieve that they are real persons fail to convince.

  18. Stedelijkheid en diversiteit : Jane Jacobs in Roombeek

    NARCIS (Netherlands)

    Straatman, E.G.P. (Elly)

    2010-01-01

    Met de vertaling van The Death and Life of Great American Cities is in Nederland een kleine Jane Jacobs-revival ontstaan met lezingen, workshops, masterclasses en een essaybundel. Jacobs’ boek kwam in de VS uit in 1961. Het was een aanval op de toenmalige praktijk van stadsplanning. Wat maakt

  19. A Geological and Geophysical Study of the Geothermal Energy Potential of Pilgrim Springs, Alaska

    Energy Technology Data Exchange (ETDEWEB)

    Turner, Donald L.; Forbes, Robert B. [eds.

    1980-01-01

    The Pilgrim Springs geothermal area, located about 75 km north of Nome, was the subject of an intensive, reconnaissance-level geophysical and geological study during a 90-day period in the summer of 1979. The thermal springs are located in a northeast-oriented, oval area of thawed ground approximately 1.5 km{sup 2} in size, bordered on the north by the Pilgrim River. A second, much smaller, thermal anomaly was discovered about 3 km northeast of the main thawed area. Continuous permafrost in the surrounding region is on the order of 100 m thick. Present surface thermal spring discharge is {approx} 4.2 x 10{sup -3} m{sup 3} s{sup -1} (67 gallons/minute) of alkali-chloride-type water at a temperature of 81 C. The reason for its high salinity is not yet understood because of conflicting evidence for seawater vs. other possible water sources. Preliminary Na-K-Ca geothermometry suggests deep reservoir temperatures approaching 150 C, but interpretation of these results is difficult because of their dependence on an unknown water mixing history. Based on these estimates, and present surface and drill hole water temperatures, Pilgrim Springs would be classified as an intermediate-temperature, liquid-dominated geothermal system.

  20. Translating Jane Austen’s Mansfield Park for contemporary Italian readers

    Directory of Open Access Journals (Sweden)

    Simona Sangiorgi

    2015-12-01

    Full Text Available Abstract - My Italian translation of the novel Mansfield Park by Jane Austen was published by Rusconi Libri in 2012. The present contribution aims to describe and discuss some aspects of my practical experience in translating this novel. A particular focus will be on the issue of what it means, from both the cultural and the literary point of view, to translate this book into Italian in the 21st century, and on the strategies I adopted in order to translate certain aspects of the author’s language and style. Riassunto - Nel 2012 è stata pubblicata la mia traduzione in lingua italiana del romanzo Mansfield Park di Jane Austen. Il presente contributo intende osservare e discutere alcuni elementi culturali e linguistici legati al processo traduttivo di questo testo, con particolare riferimento a due principali questioni. La prima riguarda il significato stesso del tradurre in lingua italiana l’opera di Jane Austen nel ventunesimo secolo, sia dal punto di vista culturale che letterario. La seconda questione entra nel merito delle strategie traduttive che ho scelto per rendere specifici aspetti del linguaggio e dello stile propri dell’autrice inglese.

  1. Jane Austen ja viktoriaanluse come back / Mihkel Mutt

    Index Scriptorium Estoniae

    Mutt, Mihkel, 1953-

    1996-01-01

    Jane Austeni teoste jätkuvalt kasvavast populaarsusest, raamatute põhjal lavastatud filmidest, viktoriaanlusest ja muust - inspireerituna filmist "Neli pulma ja üks matus" ("Four Weddings and a Funeral", rež̓issöör Mike Newell, Suurbritannia 1994)

  2. Tokyo Jane

    DEFF Research Database (Denmark)

    Austin, Robert D.; Minbaeva, Dana; Schafer, Simon

    2014-01-01

    Tokyo Jane is an accessible fashion jewelry company that makes and markets its products as “luxury for less” by designing, importing and selling fashion jewelry pieces that look luxurious but cost only a fraction of the high-priced items that inspired them. Finished products are air......-shipped to company headquarters in Copenhagen, Denmark from factories in China, stocked in the head office and delivered to 400 retail partners —small fashion boutiques, big department stores and online shops — who then sell to consumers in Europe, Scandinavia, the United Kingdom and Canada. The two partners who...... founded the firm in 2005 are facing several problems: the brand definition is not well enough developed to support the next stage in the firm’s growth, certain challenges have outstripped available human resources — they have only three permanent employees and a revolving number of interns...

  3. Resistance to inhibitors of cholinesterase (Ric-8A and Gαi contribute to cytokinesis abscission by controlling vacuolar protein-sorting (Vps34 activity.

    Directory of Open Access Journals (Sweden)

    Cedric Boularan

    Full Text Available Resistance to inhibitors of cholinesterase (Ric-8A is a guanine nucleotide exchange factor for Gαi, Gαq, and Gα12/13, which is implicated in cell signaling and as a molecular chaperone required for the initial association of nascent Gα subunits with cellular membranes. Ric-8A, Gαi subunits, and their regulators are localized at the midbody prior to abscission and linked to the final stages of cell division. Here, we identify a molecular mechanism by which Ric-8A affects cytokinesis and abscission by controlling Vps34 activity. We showed that Ric-8A protein expression is post-transcriptionally controlled during the cell cycle reaching its maximum levels at mitosis. A FRET biosensor created to measure conformational changes in Ric-8A by FLIM (Fluorescence Lifetime Imaging Microscopy revealed that Ric-8A was in a close-state during mitosis and particularly so at cytokinesis. Lowering Ric-8A expression delayed the abscission time of dividing cells, which correlated with increased intercellular bridge length and multinucleation. During cytokinesis, Ric-8A co-localized with Vps34 at the midbody along with Gαi and LGN, where these proteins functioned to regulate Vps34 phosphatidylinositol 3-kinase activity.

  4. Genetic Characterization of the Gut Microbiome of Hajj Pilgrims

    KAUST Repository

    Beaudoin, Christopher

    2018-05-01

    Hajj, the annual Islamic pilgrimage to Makkah, Saudi Arabia, is a unique mass gathering event that brings more than 2 million individuals from around the world. Several public health considerations, such as the spread of infectious diseases, must be taken into account with this large temporary influx of people. Gastrointestinal diseases, such as diarrhea, are common at Hajj, yet little is known about the etiology. The human gut microbiome, collection of organisms residing within the intestinal tract, has been under intense study recently, since next generation DNA sequencing technologies allow for extensive surveying of genetic material found in complex biological samples, such as those containing many different organisms. Thus, using 16S rRNA and metagenomic shotgun sequencing, we have characterized the gut microbiome of over 612 pilgrims with and without diarrhea. Several metadata factors, such as hospitalization and different comorbidities, were found to have significant effects on the overall gut microbiome composition. Metagenomic shotgun sequencing efforts revealed the presence of antimicrobial resistance genes originating from disparate regions from around the world. This study provides a snapshot of information concerning the health status of the gut microbiome of Hajj pilgrims and provides more context to the investigation of how to best prepare for mass gathering events.

  5. An Comparative Study of Jane Eyre's Fate and Tess's Fate from Femi?nist Viewpoint

    Institute of Scientific and Technical Information of China (English)

    CHEN Jing; HE Ling-jing

    2017-01-01

    In"Jane Eyre", Charlotte Bronte's masterpiece the heroine, Jane Eyre has fully reflected her self-esteem, equality, and pure personality, which are also reflected in her concept of love vividly. However, Thomas Hardy's Tess is poor and kind, but she does not have a complete love like Jane Eyre, and she is described by his criticism of the old moral character with good vir-tues in the traditional sense. She is a new image of modern feminism who suffered from the old moral sense and gradually has re-volt consciousness. From the feminism viewpoint, this paper attempts to analysis the causes of their different fate from different points and reveal the impact of social background on their fates.

  6. Rhetoric and Gender in Jane Austen's "Persuasion."

    Science.gov (United States)

    Walzer, Arthur E.

    1995-01-01

    Argues for a reading of Jane Austen's "Persuasion" that undermines Joseph Duffy's reading of the novel as a commentary on shifting social class structures, and which bolsters Nancy Armstrong's reading as a commentary on female voice and the values of the domestic household. Interprets the novel in the light of 18th-century rhetorical…

  7. THE COMPARISON OF INFLUENZA VACCINE EFFICACY ON RESPIRATORY DISEASE AMONG IRANIAN PILGRIMS IN THE 2003 AND 2004 SEASONS

    Directory of Open Access Journals (Sweden)

    M. Razavi

    2005-07-01

    Full Text Available Prolonged cough occurs in a large proportion of the 2 million pilgrims who participate in the annual Hajj in Saudi Arabia. There is no unique cause for pilgrims’ respiratory involvement, but several studies suggest a high incidence of influenza as a cause of the disease. To determine influenza vaccine efficacy against respiratory disease in pilgrims, we conducted two similar cohort studies on 51100 Iranian pilgrims who had participated in the annual Hajj in the years 2003 and 2004. We calculated vaccine efficacy in these two years with the use of “1- odd’s ratio” formula and compared the results. The vaccine efficacy for prevention of influenza like illness in the year 2003 was 51% but the vaccine was not efficient in the year 2004. It was concluded that etiologic agents other than influenza virus should be considered as the cause of respiratory disease in Hajj. Bacterial infections superimposed on chronic respiratory diseases, and allergic or toxic conditions are suggested caourses for more investigation.

  8. Révision de Jane Eyre comme métacommentaire philosophique dans les romans d’Anita Brookner Re-Vision of Jane Eyre as Philosophical Metacomment in the Novels of Anita Brookner

    Directory of Open Access Journals (Sweden)

    Eileen Williams-Wanquet

    2009-10-01

    Full Text Available Although none of Brookner’s twenty-three novels to date actually re-write Jane Eyre as hypotext, Brontë’s novel is part of the pervasive intertextuality of Brookner’s text, addressed here as a monolithic fiction. This omnipresent intertextuality, which is the key to understanding the whole œuvre, serves to define the moral codes followed by the heroine and to make a philosophical metacommentary on contemporary culture. Brookner’s characters read and comment on Jane Eyre, the heroine takes Jane as a role model of virtue and the masculine characters are divided into those who resemble Mr Rochester and those who belong to the same category as St John Rivers. But Brookner’s text is a re-vision of Brontë’s novel, as of other novels set in the tradition of the classic realist text and of romance, which have Cartesian rationalism and Christianity as philosophical underpinnings. Brookner reverses the poetic justice of Jane Eyre, which is re-contextualised to fit a new moral landscape in which God is dead as ultimate justification for virtuous conduct. Whereas Jane Eyre can ultimately be read as a “Victorian romance” which preaches reason in the name of social order, by replacing the traditional happy ending by an unhappy ending in which virtue is punished and by foregrounding the disastrous effects of suppressing passion in the name of reason or self in the name of the other, Brookner announces the end of a philosophical humanistic tradition in which the subject / object or self / other opposition gives rise to a host of binary oppositions, the notion of centre validating the dominance of one of the terms of the hierarchy.

  9. Review of Barbara K. Seeber, Jane Austen and Animals

    Directory of Open Access Journals (Sweden)

    Lucinda Cole

    2015-03-01

    Full Text Available In this review of Barbara K. Seeber's Jane Austen and Animals (Ashgate, 2013 Lucinda Cole summarizes this foundational book and emphasizes the role of animal studies scholars in linking feminism and environmental issues.

  10. The CaloRIC ASIC: Signal Processing for High Granularity Calorimeter

    International Nuclear Information System (INIS)

    Royer, L; Manen, S; Soumpholphakdy, X; Bonnard, J; Gay, P

    2013-01-01

    A readout ASIC called CaloRIC, has been developed to fulfil the signal processing requirements for the Silicon-Tungsten (Si-W) electromagnetic calorimeter of the International Linear Collider (ILC). This ASIC performs the complete processing of the signal delivered by the Si-PIN diode of the detector: charge sensitive amplification, shaping, analog memorization and digitization. Measurements show a global integral non-linearity better than 0.2% for low energy particles, and limited to 2% for high energy particles. The measured Equivalent Noise Charge (ENC) is evaluated at 0.6 fC, which corresponds to 1/6 times the signal released by a Minimum Ionizing Particle (MIP). With the timing sequence of the ILC, the power consumption of the complete channel is evaluated at 43 μW using a power pulsing. A new ASIC (CaloRIC 4 ch) with four improved readout channels has been designed and is ready for manufacturing.

  11. Jane Fonda võitis Cannes'is eriauhinna / Valner Valme

    Index Scriptorium Estoniae

    Valme, Valner, 1970-

    2007-01-01

    Cannes'i filmifestivalil jagati auhindu. Ameerika näitleja Jane Fonda sai elutöö auhinna, Kuldse Palmioksa sai rumeenlase Christian Mungiu "Neli kuud, kolm nädalat ja kaks päeva". Ka programmi "Vaatenurk" auhindadest

  12. Optimizing Frozen Sample Preparation for Laser Microdissection: Assessment of CryoJane Tape-Transfer System®.

    Directory of Open Access Journals (Sweden)

    Yelena G Golubeva

    Full Text Available Laser microdissection is an invaluable tool in medical research that facilitates collecting specific cell populations for molecular analysis. Diversity of research targets (e.g., cancerous and precancerous lesions in clinical and animal research, cell pellets, rodent embryos, etc. and varied scientific objectives, however, present challenges toward establishing standard laser microdissection protocols. Sample preparation is crucial for quality RNA, DNA and protein retrieval, where it often determines the feasibility of a laser microdissection project. The majority of microdissection studies in clinical and animal model research are conducted on frozen tissues containing native nucleic acids, unmodified by fixation. However, the variable morphological quality of frozen sections from tissues containing fat, collagen or delicate cell structures can limit or prevent successful harvest of the desired cell population via laser dissection. The CryoJane Tape-Transfer System®, a commercial device that improves cryosectioning outcomes on glass slides has been reported superior for slide preparation and isolation of high quality osteocyte RNA (frozen bone during laser dissection. Considering the reported advantages of CryoJane for laser dissection on glass slides, we asked whether the system could also work with the plastic membrane slides used by UV laser based microdissection instruments, as these are better suited for collection of larger target areas. In an attempt to optimize laser microdissection slide preparation for tissues of different RNA stability and cryosectioning difficulty, we evaluated the CryoJane system for use with both glass (laser capture microdissection and membrane (laser cutting microdissection slides. We have established a sample preparation protocol for glass and membrane slides including manual coating of membrane slides with CryoJane solutions, cryosectioning, slide staining and dissection procedure, lysis and RNA extraction

  13. Conversations with Miss Jane

    Directory of Open Access Journals (Sweden)

    Geneviève Fabre

    2006-05-01

    Full Text Available Considering the wide range of conversations in the autobiography, this essay will attempt to appraise the importance of these verbal exchanges in relation to the overall narrative structure of the book and to the prevalent oral tradition in Louisiana culture, as both an individual and communal expression. The variety of circumstances, the setting and staging, the interlocutors , and the complex intersection of time and place, of stories and History, will be examined; in these conversations with Miss Jane many actors participate, from  the interviewer-narrator, to most characters; even the reader becomes involved.Speaking, hearing, listening, keeping silent is an elaborate ritual that performs many functions; besides conveying news or rumors, it imparts information on the times and on the life of a “representative” woman whose existence - spanning a whole century- is both singular and emblematic. Most importantly this essay will analyse the resonance of an eventful and often dramatic era on her sensibility and conversely show how her evolving sensibility informs that history and draws attention to aspects that might have passed unnoticed or be forever silenced. Jane’s desire for liberty and justice is often challenged as she faces the possibilities of life or death.Conversations build up a complex, often contradictory, but compelling portrait: torn between silence and vehemence, between memories and the urge to meet the future, Jane summons body and mind to find her way through the maze of a fast changing world; self-willed and obstinate she claims her right to speak, to express with wit and wisdom her firm belief in the word, in the ability to express deep seated convictions and faith and a whole array of feelings and emotions.

  14. Handlen og væren. Paul Ricœurs polytetiske refleksionsteori

    DEFF Research Database (Denmark)

    Pallesen, Carsten

    erläutert, wie sich die Hermeneutik des Selbst als eine hegelsche Verschiebung der herkömmlichen Subjektsphilosophie verstehen lässt, die jedoch Hegels Begriff des absoluten Wissens durch den Begriff der Bezeugung (attestation) ersetzt. Dieser Begriff wird profiliert in einer textnahen Lektüre von Ricœurs...... Auseinandersetzung mit Husserl, Heidegger und Lévinas, in der Körper, Gewissen und der Andere als konstituierende Passivitätserfahrungen ausgelegt werden, die als solche das Verständnis des Anderssein als ontologischen Begriff für das Selbst begründen. Der fünfte Hauptteil beleuchtet die Attestationshermeneutik...... in zwei unterschiedlichen vorphilosophischen Bereichen: Psychoanalyse und Theologie. Hier wird Ricœurs Theorie der Erinnerung und sein Begriff des Gewissens in gerechtigkeitstheoretischer Perspektive erörtert, die eine gewisse Distanz zu realphilosophischen Bereichen wie z.B. Psychoanalyse und Theologie...

  15. Recovery Act Validation of Innovative Exploration Techniques Pilgrim Hot Springs, Alaska

    Energy Technology Data Exchange (ETDEWEB)

    Holdmann, Gwen [Univ. of Alaska, Fairbanks, AK (United States)

    2015-04-30

    Drilling and temperature logging campaigns between the late 1970's and early 1980’s measured temperatures at Pilgrim Hot Springs in excess of 90°C. Between 2010 and 2014 the University of Alaska used a variety of methods including geophysical surveys, remote sensing techniques, heat budget modeling, and additional drilling to better understand the resource and estimate the available geothermal energy.

  16. Jane Austen in the High School Classroom (Open to Suggestion).

    Science.gov (United States)

    Fritzer, Penelope

    1996-01-01

    Argues that Jane Austen's novels lend themselves to the high school curriculum, and that students will discover a leisurely, rural world in which the concerns of the young people are often similar to theirs. (SR)

  17. Serological study of Bordetella Pertussis, Mycoplasma Pneumonia and Chlamydia Pneumonia in Iranian hajj pilgrims with prolonged cough illnesses: A follow-up study.

    Science.gov (United States)

    Rahimian, Masoud; HosseiniB, Mahdi

    2017-11-01

    Hajj pilgrimage is the biggest and longest mass gathering in the Muslim world. Annually, about 50% of more than 2.5 million pilgrims participating in this ritual get involved in severe devastating coughs. Most coughs continue, so the pilgrims turn back home and transmit them to family members and other people. Despite the high prevalence of coughs for many years, what causes them remains unknown. Considering the pertussis-like clinical picture of the so-called "hajj coughs", the researchers conducted a study to measure antibodies against three known common atypical bacteria, namely Bordetella Pertussis, Chlamydia Pneumonia and Mycoplasma Pneumonia. The study was done on three out of eleven groups of pilgrims from Yazd province, central Iran. The sample was selected randomly and consisted of 202 pilgrims who completed an informed consent. Their blood samples were taken, and the plasma was separated and then stored at -70 °C. After turning back from the journey, the pilgrims had their second blood samples taken. As many as 52 pilgrims failed to come for the second sampling, and two samples were broken during transportation. The final analysis was performed on the remaining 148 pairs of samples. Antibodies were already elevated in many pilgrims before the journey probably due to their old age (causing more exposure to pathogens) or unplanned pertussis vaccination. After their return, antibody elevation was only mild, again probably due to the old age of the participants (i.e. due to their weaker immune systems). Some antibodies even fell down without any known reason. In this study, previous hajj journey was assumed as a prophylactic factor, due to acquisition of immunity. Coughs with a prolonged pertussis-like picture were also presumed to be more related than other types of coughs to atypical pathogens. Statistical tests showed that the history of previous journeys had no prophylactic effect. Also, no correlation was found between the clinical pictures of coughs

  18. Michel Foucault et Paul Ricœur, vers un dialogue possible

    Directory of Open Access Journals (Sweden)

    Simon Castonguay

    2011-01-01

    Full Text Available Il est désormais connu que Michel Foucault s’est intéressé à la fin de sa vie à l’ ”herméneutique du sujet.” Mais cette histoire de la constitution du sujet (ou de la subjectivité fait étrangement l’économie d’une réflexion sur le rôle de la compréhension, alors que Foucault qualifie son travail d’ ”ontologie historique de nous-mêmes.” C'est sur ce point précis qu’est ici mis à l'épreuve le caractère médiateur de l’œuvre de Paul Ricœur, dont l’herméneutique du soi prend en charge une ontologie de la compréhension. Suite à ces considérations, la seconde partie de l’article cherche à démontrer que la théorie de l’agir de Ricœur peut favoriser le passage d’une reconnaissance de type objectale à une reconnaissance des capacités du sujet à se tenir pour responsable. Ce passage sera opéré directement sur le modèle d’analyse du “dernier Foucault,” c’est-à-dire son concept-clé de “processus de subjectivation.”In his later work, Michel Foucault manifested a strong interest for the “hermeneutics of the subject.” Yet this history of the constitution of the subject (or subjectivity does without any reflection on the role of understanding, even though Foucault characterizes his project as a historical ontology of ourselves. The power of mediation emphasized in the work of Paul Ricœur may help us redefine an ontology of understanding through a hermeneutics of the self. Following this, the second part of the article aims to show that Ricœur’s theory of action can facilitate a transition from the recognition of the self, first described as “objectivation,” to a recognition of the subject’s capacity to be held responsible. This passage will draw on the model of analysis in the later Foucault, specifically, on his key concept of the subjectivation process. 

  19. "Socializing Democracy": The Community Literacy Pedagogy of Jane Addams

    Science.gov (United States)

    Wendler, Rachael

    2014-01-01

    This article reclaims Jane Addams as a community literacy pedagogue and explicates her pedagogical theory through an analysis of her social thought. Addams' goal of "socializing democracy" through education led her to both encourage immigrant students to associate across difference and to assimilate into dominant literacies--tensions…

  20. Recreating Jane: “Austenland” and the Regency Theme Park

    Directory of Open Access Journals (Sweden)

    Maddalena Pennacchia

    2017-12-01

    Full Text Available In the maze of Austen’s ever-expanding textuality – with its prequels, sequels, rewritings and adaptations – it may be worth paying attention to an unpretentious little book by Shannon Hale titled Austenland (2007. The story is about the adventures of a New Yorker thirty-something with a name that says it all: Jane. Being obsessed with Mr Darcy as played by Colin Firth, she decides to be healed by her excessive Austenian fantasies (or rather to indulge in them for the last time by spending all her savings on a English Regency Theme park that promises to offer Janeites a real full immersive Austen experience. What interests me in this post-Austenian story is the embedded discourse of leisure and tourism in the age of participatory culture, when an everywoman like Jane brings to the fore the need to be more involved in re-creative activities that are triggered by reading Austen’s novels.

  1. The Austenisation of Sensibility & the Darcyfication of Jane Austen: A Reflection.

    Directory of Open Access Journals (Sweden)

    Kirpal Singh

    2009-05-01

    Full Text Available Review essay examining Jane Austen's place in literary history, and her attitudes to deeply felt emotion, unpleasant aspects of contemporary life, and sexuality. (Non-refereed article

  2. Searching for Bill and Jane: Electronic Full-Text Literature.

    Science.gov (United States)

    Still, Julie; Kassabian, Vibiana

    1998-01-01

    Examines electronic full-text literature available on the World Wide Web and on CD-ROM. Discusses authors and genres, electronic texts, and fees. Highlights Shakespeare, Jane Austen, and nature writing. Provides a bibliography of Web guides, specialized Shakespeare pages, and pages dealing with the Shakespeare authorship debate and secondary…

  3. Induced Recall of Jane Austen's Novels: Films, Television, Videos.

    Science.gov (United States)

    Diaz de Chumaceiro, Cora L.

    2000-01-01

    Notes that the popularity of Jane Austen adaptations in theaters, television, and videos increases the probability that patients and therapists may recall these movies in treatment. Underscores excerpts from a comparison of an Austen novel with the psychoanalytic process and highlights available film adaptations in video format. (SC)

  4. Jane Marcet and Harriet Martineau: Pioneers of Economics Education.

    Science.gov (United States)

    Shackleton, J. R.

    1990-01-01

    Presents the lives and careers of Jane Marcet and Harriet Martineau and their contributions to the dissemination and popularization of political economics in early nineteenth-century education. Places their ideas about laissez-faire capitalism in historical context. Stresses the significance of their role as female writers and educators. (CH)

  5. Conference-concert with Frédéric Bernachon on Thursday, 8 March at 6 pm

    CERN Multimedia

    Staff Association

    2018-01-01

    The Staff Association is pleased to invite you to an educational conference-concert of classical piano by Frédéric Bernachon « Beethoven : sa vie et son destin au cœur de la sonate Pathétique » on Thursday, 8 March at 6 pm Main Auditorium (500-1-001) Length: 60-90 minutes. Free entrance, cocktails served after the concert. External visitors, please contact the Staff Association for a visitor card: staff.association@cern.ch or +41 22 76 63738 With the help of a piano, Frédéric Bernachon proposes to explain the tragedy of Beethoven, as transmitted in his musical legacy. The listeners will get to experience Ludwig van Beethoven's destiny, suspense, drama and great questions in all their range and variety. After a careful introduction to listening to Sonate Pathétique, Frédéric Bernachon himself interprets this unique piece, through which Beethowen has chosen...

  6. Pattern of cardiovascular diseases in pilgrims admitted in Al-Noor hospital Makkah during hajj 1429 H

    International Nuclear Information System (INIS)

    Serafi, A.S.

    2010-01-01

    The number of Hajj pilgrims is increasing every year, and has crossed the huge figure of 2 million. During Hajj period of 1428H (2007G), cardiac problems have been reported as one of the commonest causes of admissions in hospitals. However, the data regarding their Nationalities, age and gender is not available in the literature. This study was carried out to identify the cardiovascular diseases in Hajj pilgrims for the year 1429 H (2008G) classified on geographical, age and gender basis, and to suggest pre-Hajj measures for their home countries and their handling by concerned Ministry during Hajj. Methods: On retrospective basis, data of all patients belonging to different Nationalities of various regions of the world, their age and gender, was analysed, who were admitted in the Coronary Care Unit (CCU) and cardiology wards at Al- Noor Specialist Hospital Makkah, over a period of 15 days in Hajj season 1429H (2008G). Results: Out of 203 patients hospitalised, the majority (94%) were older, i.e., >45 years. The patients suffering from various cardiac diseases were in the following order: heart failure cases 67%; ischemic heart disease 21.7%; and valvular heart disease 11.3%. As an outcome of total admissions (hospitalisation), 84% patients were discharged in stable condition, 9% were discharged against medical advice, 4.5% were unable to perform Hajj and 2.5% patients died. Most common cardiac diseases were found in hospitalized patients for Hajj 1429 H, which belongs to different countries over the globe. It indicate loop holes in the health services of their home countries not verifying the physical fitness of their pilgrims before allowing them to proceed for Hajj. This study will also serve as a helping tool for the Ministry of Hajj in Saudi Arabia to take appropriate measures for demanding strictness for the physical fitness of Hajj pilgrims and anticipated health services for them. (author)

  7. Y. Laberge on Frédéric Salmon's Atlas historique des États-Unis.

    Directory of Open Access Journals (Sweden)

    2010-06-01

    Full Text Available Frédéric Salmon, Atlas historique des États-Unis de 1783 à nos jours. Paris: Armand Colin, 2008. Pp.127. ISBN-13: 978-2200347604  This new, cultural, historical atlas of United States was entirely conceived by a French geographer named Frédéric Salmon; this is not a mere collection of old or already existing maps, but rather a brand new group of unique maps related to the geography, history and demographics of the USA, from the late 18th century to the early 21st century. It should not be mix...

  8. Geophysical investigations of the geologic and hydrothermal framework of the Pilgrim Springs Geothermal Area, Alaska

    Science.gov (United States)

    Glen, Jonathan; McPhee, Darcy K.; Bedrosian, Paul A.

    2014-01-01

    Pilgrim Hot Springs, located on the Seward Peninsula in west-central Alaska, is characterized by hot springs, surrounding thawed regions, and elevated lake temperatures. The area is of interest because of its potential for providing renewable energy for Nome and nearby rural communities. We performed ground and airborne geophysical investigations of the Pilgrim Springs geothermal area to identify areas indicative of high heat flow and saline geothermal fluids, and to map key structures controlling hydrothermal fluid flow. Studies included ground gravity and magnetic measurements, as well as an airborne magnetic and frequency-domain electromagnetic (EM) survey. The structural and conceptual framework developed from this study provides critical information for future development of this resource and is relevant more generally to our understanding of geothermal systems in active extensional basins. Potential field data reveal the Pilgrim area displays a complex geophysical fabric reflecting a network of intersecting fault and fracture sets ranging from inherited basement structures to Tertiary faults. Resistivity models derived from the airborne EM data reveal resistivity anomalies in the upper 100 m of the subsurface that suggest elevated temperatures and the presence of saline fluids. A northwest trending fabric across the northeastern portion of the survey area parallels structures to the east that may be related to accommodation between the two major mountain ranges south (Kigluaik) and east (Bendeleben) of Pilgrim Springs. The area from the springs southward to the range front, however, is characterized by east-west trending, range-front-parallel anomalies likely caused by late Cenozoic structures associated with north-south extension that formed the basin. The area around the springs (~10 km2 ) is coincident with a circular magnetic high punctuated by several east-west trending magnetic lows, the most prominent occurring directly over the springs. These features

  9. Pilgrimage and Pilgrim Hierarchies in Vernacular Discourse: Comparative Notes from the Camino de Santiago and Glastonbury

    Directory of Open Access Journals (Sweden)

    Tiina Sepp

    2014-06-01

    Full Text Available 0 false 18 pt 18 pt 0 0 false false false This article is based on my fieldwork conducted in two important destinations in the spiritual landscape of European vernacular religion – the Camino de Santiago (pilgrimage route to Santiago de Compostela in northern Spain, and Glastonbury in southwest England. In this comparison between modern expressions of pilgrimage, I look into the power relationships that exist on the pilgrimage, describe how hierarchies of pilgrims are created and maintained, and reflect on the meaning of the words pilgrim and pilgrimage. The co-existence of the different belief systems of Christianity and New Age and the conflicts and tension between them will be explored. I will also examine discourse around competing male and female energies. 

  10. Paul Ricœur: Variations et continuité d'un projet politique

    Directory of Open Access Journals (Sweden)

    Pierre-Olivier Monteil

    2013-01-01

    Full Text Available Les commentateurs s’accordent pour constater une évolution dans la pensée politique de Ricœur conduisant d’un radicalisme à un réformisme. Par-delà ces variations, on se propose plutôt de mettre en évidence la continuité d’un projet. Non seulement la critique du capitalisme se poursuit jusqu’au bout, mais la perspective du socialisme semble très tôt tenue pour improbable. Dans les deux cas, la préoccupation centrale porte sur la nécessité de raviver les traditions et de faire émerger l’élan initial sous la doctrine “ossifiée ” en les situant en tension critique entre elles pour qu’elles se corrigent mutuellement. Le projet politique de Ricœur consiste à établir en vis-à-vis libéralisme et socialisme.

  11. Consensus recommendation for India and Bangladesh for the use of pneumococcal vaccine in mass gatherings with special reference to Hajj pilgrims

    Directory of Open Access Journals (Sweden)

    Dilip Mathai

    2016-01-01

    Full Text Available Respiratory tract infections are prevalent among Hajj pilgrims with pneumonia being a leading cause of hospitalization. Streptococcus pneumoniae is a common pathogen isolated from patients with pneumonia and respiratory tract infections during Hajj. There is a significant burden of pneumococcal disease in India, which can be prevented. Guidelines for preventive measures and adult immunization have been published in India, but the implementation of the guidelines is low. Data from Bangladesh are available about significant mortality due to respiratory infections; however, literature regarding guidelines for adult immunization is limited. There is a need for extensive awareness programs across India and Bangladesh. Hence, there was a general consensus about the necessity for a rapid and urgent implementation of measures to prevent respiratory infections in pilgrims traveling to Hajj. About ten countries have developed recommendations for pneumococcal vaccination in Hajj pilgrims: France, the USA, Kuwait, Qatar, Bahrain, the UAE (Dubai Health Authority, Singapore, Malaysia, Egypt, and Indonesia. At any given point whether it is Hajj or Umrah, more than a million people are present in the holy places of Mecca and Madina. Therefore, the preventive measures taken for Hajj apply for Umrah as well. This document puts forward the consensus recommendations by a group of twenty doctors following a closed-door discussion based on the scientific evidence available for India and Bangladesh regarding the prevention of respiratory tract infections in Hajj pilgrims.

  12. Prevalence of MERS-CoV nasal carriage and compliance with the Saudi health recommendations among pilgrims attending the 2013 Hajj.

    Science.gov (United States)

    Memish, Ziad A; Assiri, Abdullah; Almasri, Malak; Alhakeem, Rafat F; Turkestani, Abdulhafeez; Al Rabeeah, Abdullah A; Al-Tawfiq, Jaffar A; Alzahrani, Abdullah; Azhar, Essam; Makhdoom, Hatem Q; Hajomar, Waleed H; Al-Shangiti, Ali M; Yezli, Saber

    2014-10-01

    Annually, Saudi Arabia is the host of the Hajj mass gathering. We aimed to determine the Middle East respiratory syndrome coronavirus (MERS-CoV) nasal carriage rate among pilgrims performing the 2013 Hajj and to describe the compliance with the Saudi Ministry of Health vaccine recommendations. Nasopharyngeal samples were collected from 5235 adult pilgrims from 22 countries and screened for MERS-CoV using reverse transcriptase-polymerase chain reaction. Information regarding the participants' age, gender, country of origin, medical conditions, and vaccination history were obtained. The mean age of the screened population was 51.8 years (range, 18-93 years) with a male/female ratio of 1.17:1. MERS-CoV was not detected in any of the samples tested (3210 pre-Hajj and 2025 post-Hajj screening). According to the vaccination documents, all participants had received meningococcal vaccination and the majority of those from at-risk countries were vaccinated against yellow fever and polio. Only 22% of the pilgrims (17.5% of those ≥65 years and 36.3% of diabetics) had flu vaccination, and 4.4% had pneumococcal vaccination. There was no evidence of MERS-CoV nasal carriage among Hajj pilgrims. While rates of compulsory vaccinations uptake were high, uptake of pneumococcal and flu seasonal vaccinations were low, including among the high-risk population. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  13. No Space. Nowhere. Refugees and the Problem of Human Rights in Arendt and Ricœur.

    Directory of Open Access Journals (Sweden)

    Hille Haker

    2018-02-01

    Full Text Available In the wake of the recent global refugee and migration crisis, Hannah Arendt’s defense of the right to have political rights has become prominent again. Her work is read as an early reminder that the internationally promoted human rights regime may be merely a rhetorical reference, without the will or international authority for political action. I examine Arendt’s analysis in its historical context and then turn to consider Ricœur’s understanding of human rights. The capability to respond to and to be held accountable by others marks Ricœur’s ethics of responsibility. He agrees with Arendt that legal authority must rest upon power (Macht and not domination (Herrschaft, but he insists that the undercurrent of common power is the moral capability of an agent. The essay examines the ramifications of Ricœur’s ethics for the current crisis of refugees and migration, and it argues that he offers, at the same time, a correction useful for the ethical foundation of human rights.

  14. STUDI KELAYAKAN MAKAM KERAMAT AGUNG PEMECUTAN SEBAGAI DAYA TARIK WISATA PILGRIM DI DENPASAR (ANALISIS ASPEK PASAR DAN PEMASARAN

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    Ashmi Hudaningsih

    2014-06-01

    Full Text Available Makam Keramat Agung Pemecutan is one of the pilgrim tourism potentials in Denpasar. To avoid stagnant or decline position of Makam Keramat Agung Pemecutan development as a pilgrim tourist attraction, it is necessary to do a feasibility study. The most important and first aspect in feasibility study is market and marketing aspects.This study aims to determine the feasibility of market and marketing aspects of Makam Keramat Agung Pemecutan wich views from the market potential and the position of Makam Keramat Agung Pemecutan compared with its competitors, and make the right marketing strategy for Makam Keramat Agung Pemecutan in its development into a pilgrim tourist attraction. The results of this study shows that potential market of Makam Keramat Agung Pemecutan is domestic tourists who are Muslims. From the analysis of the competitive profile matrix shows Makam Keramat Agung Pemecutans position more competitive than its competitors. Therefore, Makam Keramat Agung Pemecutan is feasible on the market and marketing aspects. The suggestions provided are should establish management organization, make promotional activities, add facilities, and maintaining product quality of Makam Keramat Agung Pemecutan, continue this research about feasibility of Makam Keramat Agung Pemecutan in the other aspects especially culture aspect.

  15. Stedelijkheid en diversiteit: Jane Jacobs in Roombeek

    OpenAIRE

    Straatman, E.G.P. (Elly)

    2010-01-01

    Met de vertaling van The Death and Life of Great American Cities is in Nederland een kleine Jane Jacobs-revival ontstaan met lezingen, workshops, masterclasses en een essaybundel. Jacobs’ boek kwam in de VS uit in 1961. Het was een aanval op de toenmalige praktijk van stadsplanning. Wat maakt het boek anno 2010 nog actueel? Elly Straatman gaat in deze bijdrage in op Jacobs’ visie op vitale stadsbuurten en generatoren van stedelijkheid. Ze bekijkt hoe in de Enschedese wijk Roombeek...

  16. Women Consciousness Exploration in Jane Austen and Her Works

    Science.gov (United States)

    He, Xiaojun; Liao, Lina

    2015-01-01

    Jane Austen is one of the greatest realistic novelists in English literature of the 19th century. Austen is contrary to consciousness of man centrism and traditional values of masculine writers before her time. All her 6 novels are concerned with love and marriage; they truthfully reflect women life of her age, reveals her feminine consciousness…

  17. Concrete Security for Entity Recognition: The Jane Doe Protocol

    DEFF Research Database (Denmark)

    Lucks, Stefan; Zenner, Erik; Weimerskirch, Andre

    2008-01-01

    Entity recognition does not ask whether the message is from some entity X, just whether a message is from the same entity as a previous message. This turns turns out to be very useful for low-end devices. The current paper proposes a new protocol – the “Jane Doe Protocol” –, and provides a formal...

  18. The guanine nucleotide exchange factor RIC8 regulates conidial germination through Gα proteins in Neurospora crassa.

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    Carla J Eaton

    Full Text Available Heterotrimeric G protein signaling is essential for normal hyphal growth in the filamentous fungus Neurospora crassa. We have previously demonstrated that the non-receptor guanine nucleotide exchange factor RIC8 acts upstream of the Gα proteins GNA-1 and GNA-3 to regulate hyphal extension. Here we demonstrate that regulation of hyphal extension results at least in part, from an important role in control of asexual spore (conidia germination. Loss of GNA-3 leads to a drastic reduction in conidial germination, which is exacerbated in the absence of GNA-1. Mutation of RIC8 leads to a reduction in germination similar to that in the Δgna-1, Δgna-3 double mutant, suggesting that RIC8 regulates conidial germination through both GNA-1 and GNA-3. Support for a more significant role for GNA-3 is indicated by the observation that expression of a GTPase-deficient, constitutively active gna-3 allele in the Δric8 mutant leads to a significant increase in conidial germination. Localization of the three Gα proteins during conidial germination was probed through analysis of cells expressing fluorescently tagged proteins. Functional TagRFP fusions of each of the three Gα subunits were constructed through insertion of TagRFP in a conserved loop region of the Gα subunits. The results demonstrated that GNA-1 localizes to the plasma membrane and vacuoles, and also to septa throughout conidial germination. GNA-2 and GNA-3 localize to both the plasma membrane and vacuoles during early germination, but are then found in intracellular vacuoles later during hyphal outgrowth.

  19. ‘Gaze’ and ‘Visuality’ in Jane Austen’s Pride and Prejudice

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    Zolfagharkhani M.

    2012-01-01

    Full Text Available For many readers, there is no connection between Jane Austen’s novels and the sexualized body. Sexuality in Austen’s novels is never explicit; nonetheless, it permeates every look, gesture, and letter that passes between her lovers. This article aims to reveal the concept of ‘gaze’, especially female gaze, in Jane Austen’s Pride and Prejudice. According to feminist critics it is psychologically inevitable that women are the sexual objects of men; therefore, they have effectively refused to acknowledge the possibility that a female gaze could exist. Arguably, as it is indicated throughout this article, women are not necessarily rendered mute and inert by the male gaze; in fact, they actively shape and respond to male desire and their gaze encompasses as much authority and power as the male gaze.

  20. Pilgrim Souvenir: Hood of Cherries

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    Amy Jeffs

    2017-06-01

    Full Text Available This lead alloy badge from the British Museum represents a medieval hood repurposed as a sack for a harvest of cherries. It measures 38 by 30 millimetres and was cast integrally with its pin and clasp in a three-part mould. When first made, it would have shone like silver. Badges were purchased in their millions by pilgrims between the late twelfth and early sixteenth centuries, as attractive, wearable and cheap souvenirs of their visits to holy sites. By the later Middle Ages badges were also worn as general symbols of devotion, as livery insignia, and as humorous or amorous tokens; which of these categories the “hood of cherries” badge falls into is debatable. Five of them have been found: three in Salisbury, and another in London, while the provenance of the fifth is unknown. Their cataloguers reluctantly associate them with the cult of St Dorothy, whose emblem is a basket of fruit, although Spencer expressed concern that, “a fashionable hood seems far removed from her story.” There are also possible alternative explanations to its meaning, which will be explored here.

  1. Jane Fonda: Repercussions of Her 1972 Visit to North Vietnam

    Science.gov (United States)

    2010-04-01

    prisoner said, “we almost went fucking crazy.” 45 She referred to the pilots as “American imperialist air raiders”. 46 The guards broadcast a...taped recording of Fonda singing with a group of women; the song was called “ Fuck the Army”. 47 The much-publicized meeting of Jane Fonda

  2. Interjections in the Performance of Jane Austen's "Pride and Prejudice"

    Science.gov (United States)

    O'Connell, Daniel C.; Kowal, Sabine

    2010-01-01

    Three data sets of primary and secondary interjections were compared: (1) the original interjections written into the text of Jane Austen's (1813/1994) novel "Pride and prejudice"; (2) the interjections read aloud in commercial recordings by six professional readers of the entire text of the novel; (3) the interjections spoken by actresses and…

  3. Adèle, version abâtardie de Jane Eyre Adèle, an “Addled” Version of Jane Eyre?

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    Claire Bazin

    2009-10-01

    Full Text Available Adèle is a rewriting of the story of Jane Eyre published 150 years before. Emma Tennant, who is a specialist in the field of « revisions » puts Adèle, Jane’s young pupil in the Ur-text, in the limelight by giving her a « story  of her own », as if she were taking her revenge on the original text which had given her so insignificant a part.

  4. Chemical chaperones exceed the chaperone effects of RIC-3 in promoting assembly of functional α7 AChRs.

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    Alexander Kuryatov

    Full Text Available Functional α7 nicotinic acetylcholine receptors (AChRs do not assemble efficiently in cells transfected with α7 subunits unless the cells are also transfected with the chaperone protein RIC-3. Despite the presence of RIC-3, large amounts of these subunits remain improperly assembled. Thus, additional chaperone proteins are probably required for efficient assembly of α7 AChRs. Cholinergic ligands can act as pharmacological chaperones to promote assembly of mature AChRs and upregulate the amount of functional AChRs. In addition, we have found that the chemical chaperones 4-phenylbutyric acid (PBA and valproic acid (VPA greatly increase the amount of functional α7 AChRs produced in a cell line expressing both α7 and RIC-3. Increased α7 AChR expression allows assay of drug action using a membrane potential-sensitive fluorescent indicator. Both PBA and VPA also increase α7 expression in the SH-SY5Y neuroblastoma cell line that endogenously expresses α7 AChRs. VPA increases expression of endogenous α7 AChRs in hippocampal neurons but PBA does not. RIC-3 is insufficient for optimal assembly of α7 AChRs, but provides assay conditions for detecting additional chaperones. Chemical chaperones are a useful pragmatic approach to express high levels of human α7 AChRs for drug selection and characterization and possibly to increase α7 expression in vivo.

  5. Jane Air: The Heroine as Caged Bird in Charlotte Brontë’s Jane Eyre and Alfred Hitchcock’s Rebecca L’héroïne, oiseau en cage dans Jane Eyre de Charlotte Brontë et Rebecca d’Alfred Hitchcock

    Directory of Open Access Journals (Sweden)

    Paul Marchbanks

    2009-12-01

    Full Text Available Dans le quatrième chapitre de son ouvrage intitulé Brontë Transformations (1996, Patsy Stoneman révèle l’importance des reprises et transformations dont a fait l’objet Jane Eyre (1847 de Charlotte Brontë dans diverses pièces de théâtre, romans et films depuis sa publication initiale. L’un des avatars les plus intéressants mentionné par P. Stoneman est Rebecca d’Alfred Hitchcock (1940 d’après le roman à succès éponyme de Daphné Du Maurier paru en 1938. Parmi les nombreux éléments communs au roman de Brontë et au film d’Hitchcock figurent l’héroïne orpheline consciente de son physique ordinaire, un personnage masculin maussade doté d’une épouse “présente-absente” et une intendante dont le tempérament influence l’atmosphère du manoir dans lequel l’héroïne réside temporairement. Un autre point commun, plus difficile à déceler car profondément intégré à chaque œuvre, est le portrait de l’héroïne en oiseau prisonnier. Ce(tte subtile trope/métaphore mérite d’être remarqué(e car non seulement l’image constitue un lien entre les deux œuvres mais elle permet aussi, dans ses diverses manifestations, de les différencier. Tandis que dans Jane Eyre, l’image de l’oiseau apparaît chaque fois que Jane s’échappe d’un lieu qui l’emprisonne, celle de la cage s’avère être l’élément dominant dans le film d’Hitchcock, imposant finalement des limites infranchissables à la liberté de l’héroïne.

  6. Did the "Woman in the Attic" in Jane Eyre Have Huntington Disease?

    Science.gov (United States)

    Coon, Elizabeth A; Hassan, Anhar

    2015-01-01

    References to neurologic disorders are frequently found in fictional literature and may precede description in the medical literature. Our aim was to compare Charlotte Brontë's depiction of Bertha Mason in Jane Eyre to the tenets set forth in George Huntington's original essay "On chorea" with the hypothesis that Mason was displaying features of Huntington disease. Charlotte Brontë's 1847 Victorian novel Jane Eyre features the character Bertha Mason, who is portrayed with a progressive psychiatric illness, violent movements, and possible cognitive decline. Similar to Huntington's tenets, Mason has a disorder with a strong family history suggestive of autosomal dominant inheritance with onset in adulthood, and culminating in suicide. Brontë's character had features of Huntington disease as originally described by Huntington. Brontë's keen characterization may have increased awareness of treatment of neuropsychiatric patients in the Victorian era.

  7. Jane Doe: a cautionary tale for case reports.

    Science.gov (United States)

    Putnam, Frank W

    2014-12-01

    Historically, clinical case reports have played an essential role in the professional communication of medical and psychiatric knowledge. Case reports continue to play important roles in the initial identification of new syndromes or unusual variants of established conditions. Case reports and case series also serve to alert clinicians to preliminary evidence of the efficacy of novel treatments or adaptations to new populations. The Jane Doe Case provides a seminal example of the ethical/medico-legal dilemma arising from a patient's right to confidentiality versus the principle of independent review/replication as a necessary requirement for scientific credibility. As a result of being the subject of dueling case reports concerning the validity of her delayed recall of childhood sexual abuse, Jane Doe's identity was revealed. Consequently, she suffered significant emotional distress, bankruptcy, and the end of her career as a naval officer and aviator. Current medical journal guidelines call for protection of confidentiality of the patient's identity; yet, scientific credibility requires the possibility of an independent outside review if there are legitimate reasons to question facts or claims advanced in a case report. A potential solution is proposed as a starting point for resolving the dilemma posed for case study subjects and authors by the conflicting requirements of patient confidentiality and, if warranted, the possibility of an independent scientific review. © The Author(s) 2014.

  8. Resistance to Inhibitors of Cholinesterase 3 (Ric-3 Expression Promotes Selective Protein Associations with the Human α7-Nicotinic Acetylcholine Receptor Interactome.

    Directory of Open Access Journals (Sweden)

    Matthew J Mulcahy

    Full Text Available The α7-nicotinic acetylcholine receptor (α7-nAChR is a ligand-gated ion channel widely expressed in vertebrates and is associated with numerous physiological functions. As transmembrane ion channels, α7-nAChRs need to be expressed on the surface of the plasma membrane to function. The receptor has been reported to associate with proteins involved with receptor biogenesis, modulation of receptor properties, as well as intracellular signaling cascades and some of these associated proteins may affect surface expression of α7-nAChRs. The putative chaperone resistance to inhibitors of cholinesterase 3 (Ric-3 has been reported to interact with, and enhance the surface expression of, α7-nAChRs. In this study, we identified proteins that associate with α7-nAChRs when Ric-3 is expressed. Using α-bungarotoxin (α-bgtx, we isolated and compared α7-nAChR-associated proteins from two stably transfected, human tumor-derived cell lines: SH-EP1-hα7 expressing human α7-nAChRs and the same cell line further transfected to express Ric-3, SH-EP1-hα7-Ric-3. Mass spectrometric analysis of peptides identified thirty-nine proteins that are associated with α7-nAChRs only when Ric-3 was expressed. Significantly, and consistent with reports of Ric-3 function in the literature, several of the identified proteins are involved in biological processes that may affect nAChR surface expression such as post-translational processing of proteins, protein trafficking, and protein transport. Additionally, proteins affecting the cell cycle, the cytoskeleton, stress responses, as well as cyclic AMP- and inositol triphosphate-dependent signaling cascades were identified. These results illuminate how α-bgtx may be used to isolate and identify α7-nAChRs as well as how the expression of chaperones such as Ric-3 can influence proteins associating with α7-nAChRs. These associating proteins may alter activities of α7-nAChRs to expand their functionally-relevant repertoire as

  9. The book and reading in the space of performance: the case of Jane Austen Book Club

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    Carmen Irene Correa de Oliveira

    2012-05-01

    Full Text Available We propose to discuss the role of filmic narratives with the book as an object of representation in the context of the imaginary of shapes and types of knowledge, of ways of reading organization and of practices that have the book as object. Finally, we have the dialogical perspective of the works, its time, the subject readers and its context. For this project, we bring the filmic text The Jane Austen Book Club (2007, based on a book (The Jane Austen book club by Karen Joy Fowler, which focuses on personal and intimate dramas from people at different times of sharing, unfolding for six months, and that presents individual experiences which are mixed with the characters’ plots from the books of the English author. We highlight in the film, book and reading as narrative elements, characters accomplices of small dramas. In The Jane Austen Book Club, we perform an extrapolation in order to put the two moments - the performance and reading - in the practices developed by the participants of the club. They find the work of Austen in individual reading and in the performance that puts everyone in a continuous space of action and transformation. We believe, finally, that individual reading and the club meetings make it possible to think of the reception (individual reading and performance (reading/collective analysis in a combination that allows a constant revitalization of the work, in the case of Jane Austen.

  10. Jane Austen: tra brand e desiderio

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    Donata Meneghelli

    2014-12-01

    Full Text Available Che Jane Austen, dopo essere giunta a una incontrastata canonizzazione nel pantheon della letteratura occidentale, abbia recentemente intrapreso una   trionfante ascesa nell’ambito della cultura popolare è ormai “una verità universalmente riconosciuta”.   Il saggio analizza i modi, le forme, i supporti e i canali attraverso cui Jane Austen e i suoi testi narrativi (con particolare riferimento a Pride and Prejudice sono usciti dal cerchio tutto sommato ristretto dell’accademia, dei curricola universitari e dei lettori di professione, per entrare in uno spazio che è quello di YouTube, delle fan communities, della musica pop, dei blog, del romanzo rosa o dell’horror; i percorsi grazie ai quali sono diventati parte delle mitologie popolari del XXI secolo e al tempo stesso un brand di successo intorno al quale ruota una fitta rete di interessi economici (industria cinematografica e televisiva, turismo, editoria…, capace di catalizzare (e sfruttare desideri, proiezioni, aspettative di nuove tipologie di lettori; le inedite modalità di ricezione che caratterizzano questo fenomeno, e soprattutto la fan fiction, situata al punto di convergenza o di frizione tra diversi media (letteratura, cinema, televisione, web e media digitali in genere, tra produttori e consumatori, tra lettura e scrittura, tra strategie commerciali delle corporation e autarchia dei fan, tra “alto” e “basso”. Si tratta di un insieme di trasformazioni che scuote alle fondamenta le nostre consuetudini e le nostre credenze in quanto studiosi di letteratura: da una parte, emerge una nuova configurazione della testualità, euforica, rizomatica, molteplice, che si fa beffe di qualunque metafisica dell’originale e realizza in modo perverso alcune celebri utopie critiche; dall’altra, il caso Austen porta alla luce in maniera emblematica le contraddizioni latenti in qualunque processo di democratizzazione della cultura.

  11. Seeking Austen, from Abroad: Lori Smith’s Memoir 'A Walk with Jane Austen' (2007

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    Juliette Wells

    2009-05-01

    Full Text Available One outcome of Jane Austen’s popularity with present-day readers is their creation of books derived from and inspired by her own. This article examines a recent contribution to this increasingly crowded field: Lori Smith’s 2007 'A Walk with Jane Austen: A Journey into Adventure, Love & Faith', which depicts a thirtysomething American woman’s travel to England in the hopes of better understanding both Austen and herself. I consider this memoir in relation to other works created by Austen fans, including those who, like Smith, aim primarily at a Christian readership; I address as well this book’s significance as an account of literary pilgrimage and of personally transformative reading.

  12. Jane Austen on love and pedagogical power.

    Science.gov (United States)

    Fessenbecker, Patrick

    2011-01-01

    This essay notes initially recent prominence of theories of pedagogy that attempt to "de-mystify" it and reveal troubling power relations, and their subsequent contention that love is impossible in the student-teacher relationship. "Pedagogical" interpretations of Jane Austen's fiction, however, see pedagogy as essential to love. I argue that this is so precisely because of the power dynamics involved; drawing on Jessica Benjamin's psychoanalytic interpretation of G. W. F. Hegel's analysis of the "Lord-Bondsman," I suggest that Austen portrays the loving relationship as inherently involving the occupation and subsequent exchange of roles as superior and inferior, incarnated as "teacher" and "student."

  13. Captation spéculaire et mise en abyme dans le film Jane Eyre de Franco Zeffirelli Specular Captation and Metafictional Devices in Zeffirelli’s Jane Eyre

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    Isabelle Van Peteghem-Tréard

    2009-07-01

    Full Text Available This article presents Franco Zeffirelli’s baroque use of mirrors to evoke the specular alienation of Jane Eyre who is both the heroine and the story-teller in the movie and in the original text. The mirror image—or, condensed into a single word, the “mirage”—is not only whole and non-human as opposed to fragmented, turbulent and human, it is an “exteriority,” an outside that is also inside. The ego experiences a perpetual rift that is modeled on the subject’s dual relations with its specular counterpart, the other woman. The mirror stage presents through dramatic exemplification a certain level of rupture between inwardly lived and external realities. The director thus emphasizes the question of representation and its various metafictional modes as Jane Eyre—the movie— can be seen as a portrait of the artist. Drawing can be regarded as the cinematic equivalent of narration in Charlotte Brontë’s work and also as empowerment for the female subject who ultimately becomes a creator.

  14. Une espérance post-critique ? Enjeux critiques de la conception ricœurienne de l'imaginaire social

    Directory of Open Access Journals (Sweden)

    PEGGY AVEZ

    2014-12-01

    Full Text Available RésuméLa fondation anthropologique de la fonction critique – socialement endossée par l’imaginaire utopique – et son lien dynamique avec la tâche intégrative de l’idéologie permettent à Ricœur de repenser sur le plan socio-politique la double nécessité du soupçon et de l’espérance. En reliant l’analyse de la structure contradictoire et analogisante de l’imaginaire social aux perspectives antérieurement développées sur “la liberté selon l’espérance,” notre propos vise à expliciter ses enjeux émancipateurs. Les apories auxquelles les médiations symboliques contraignent l’agir doivent nourrir la double nécessité d’un “devoir de vigilance” et d’une “timide espérance”: telle est à la fois la difficulté irréductible et la force critique de l’analyse ricœurienne de l’imagination socialisante.Mots-clés: imaginaire social, critique, idéologie, utopie, espérance.AbstractThe anthropological foundation of the critical function—endorsed by the utopian imaginary—and its dynamic relation with the integrative task of ideology allow Ricœur to rethink, at a social and political level, the necessity of both suspicion and hope. Linking Ricœur’s analysis of the contradictory and analogizing structure of the social imaginary to perspectives on “freedom in the light of hope,” which were developed earlier, it is my intention to make explicit certain emancipatory issues. The aporiae to which symbolic mediations constrict acting must provide for the necessity of both an “obligation for vigilance” and a “tentative hope.” Such is the irreducible difficulty but also the critical force of Ricœur’s analysis of the socializing imagination.Keywords: Social Imaginary, Criticism, Ideology, Utopia, Hope.

  15. «O Sancta Haera». Pilgrims and Pilgrimage in the Sanctuary of Sainte Foy at Conques

    Directory of Open Access Journals (Sweden)

    Marco Papasidero

    2017-12-01

    Full Text Available The Liber miraculorum Sancte Fidis, written during the XI century, partially by Bernard of Angers, describes miracles, healings and rituals practiced in the sanctuary of Sainte Foy at Conques, martyr of the beginning of the IV century.The Liber allows us to analyze the anthropological and religious dimension of the pilgrims and their pilgrimage. As a matter of fact, through the descriptions of the pilgrims, their gestures, their aspects, their words, their ritual practices by the tomb, their rich or poor offerings, we can analyze the dimension of the Medieval pilgrimage as a specific case study, which can help us describe the idea of pilgrimage in Medieval West Europe and specifically in this sanctuary.Furthermore, through the reading of the accounts of miracle stories, we can analyze the healing ritual practices, the miraculous dimension of this cult and the Sainte’s ability to treat diseases. The center of the Conques cult was – and remains – the Majesty of Sainte Foy, a reliquary statue in which the power (virtus/dynamis of the saint’s relics is concentrated.

  16. Did the "Woman in the Attic" in Jane Eyre Have Huntington Disease?

    Directory of Open Access Journals (Sweden)

    Elizabeth A. Coon

    2015-07-01

    Full Text Available Background: References to neurologic disorders are frequently found in fictional literature and may precede description in the medical literature. Aim: Our aim was to compare Charlotte Brontë’s depiction of Bertha Mason in Jane Eyre to the tenets set forth in George Huntington’s original essay “On chorea” with the hypothesis that Mason was displaying features of Huntington disease. Results: Charlotte Brontë’s 1847 Victorian novel Jane Eyre features the character Bertha Mason, who is portrayed with a progressive psychiatric illness, violent movements, and possible cognitive decline. Similar to Huntington’s tenets, Mason has a disorder with a strong family history suggestive of autosomal dominant inheritance with onset in adulthood, and culminating in suicide. Conclusion: Brontë’s character had features of Huntington disease as originally described by Huntington. Brontë’s keen characterization may have increased awareness of treatment of neuropsychiatric patients in the Victorian era.

  17. A Bold New Timeless Classic: Fukunaga’s Partial Reading of Jane Eyre

    Directory of Open Access Journals (Sweden)

    John Engle

    2012-07-01

    Full Text Available With its first person narrator, radical tonal changes, and wild blend of genres (autobiography, romance, Gothic melodrama, Christian exemplum, etc., Brontë’s Jane Eyre is a case study in the difficulties of cinematic adaptation, as the filmmaker attempts to balance "fidelity" with contemporary relevance and entertainment value. This article examines Cary Fukunaga’s 2011 version, and in particular certain orientations animating his necessarily "partial" reading of the novel. Chief among these is the decision to begin the film when Jane leaves Thornfield; recounting much of the story in discontinuous flashback, the film manages simultaneously to admit Jane’s narrative voice while eliminating its potentially distracting nature. Fukunaga’s other choices include the toning down of the novel’s lurid Gothic quality, its overt romanticism, and—today an overly familiar romantic comedy stereotype—the teasing interplay between the two protagonists. Communicating in a compact language of visual symbol, he also uses the original’s "religious plot" as a tool for modern character analysis.

  18. A Female Interrogative Reader: The Adolescent Jane Austen Reads and Rewrites (His)tory.

    Science.gov (United States)

    Reid-Walsh, Jacqueline

    1992-01-01

    Argues that Jane Austen's unpublished juvenile work "The History of England" has considerable relevance to twentieth-century high-school English classrooms. Notes that the work humorously shows the gender bias of traditional history texts because it is a "woman-centered" rewriting. (RS)

  19. Paul Ricœur’s Search for a Just Community. The Phenomenological Presupposition of a Life “with and for others”

    Directory of Open Access Journals (Sweden)

    Marc De Leeuw

    2018-02-01

    Full Text Available The aim of this article is to examine how Ricœur’s critique of Husserl’s and Levinas’s notions of intersubjectivity informs his own alternative conceptualization of the intra- and interpersonal as a complex intertwining of moral selfhood and a just community. My first assumption is that law, as a prescriptive intervention in the social structure of our communal life, presupposes a phenomenology of our “being with others”. My second assumption is that Ricœur’s entire philosophical anthropology, and specifically his ideas on ethics, legality and justice, can be read as a prolonged response to Husserl’s solipsistic deadlock in the famous Fifth Cartesian Meditation. Taken together these two assumptions connect Ricœur’s early analysis of phenomenology with his complex reconceptualization of moral selfhood in Oneself as Another, culminating in the ethical maxim of “a good life with and for others in just institutions.”

  20. Matriz binária RiC: classificação filogenética da informação arquivística

    OpenAIRE

    Macedo, Laureano Secundino Ascensão de

    2017-01-01

    Ascensão de Macedo, L. S., 2017, "Matriz binária RiC: classificação filogenética da informação arquivística", doi:10.7910/DVN/ERE8HL, Harvard Dataverse, V1 Constam três folhas: 1 - matriz binária com propriedades RiC e taxa (tipologias documentais); 2 - matriz binária simples (processamento em DendroUPGMA); 3 - 3 outputs de DendroUPGMA: matriz bicaudal de similaridade, de distâncias e formato Newick. (2017-01-18)

  1. Jane Austen (1775-1817) and the cultural history of health.

    Science.gov (United States)

    Biddiss, Michael

    2014-08-01

    This paper provides a review of some aspects of the life and novels of Jane Austen that have particular bearing on her approach to issues of sickness and health. It is based on a Keynote Lecture given at the Annual Congress of the British Society for the History of Medicine on 1 September 2011 at the University of Surrey. © IMechE 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  2. Case study: Massachusetts Department of Public Health's Southeastern Massachusetts health study on leukemia around Pilgrim Nuclear Power Station: Who won?

    Energy Technology Data Exchange (ETDEWEB)

    Flanagan, Anita [Boston Edison Company (United States)

    1993-07-01

    In October 1990, the Massachusetts Department of Public Health released their Southeastern Massachusetts health study. This is a study of leukemia incidence in 22 towns around Pilgrim NPP, for the period 1978 through 1986. Pilgrim Station had been returned to operation following a 3 year outage, from 1986-1989. During this period, some $300 million in capital outlay was invested by Boston Edison in upgrading safety systems and installing the so-Called Three Mile Island upgrades. A copy of the peer review panel report is attached to this paper. Because of the interest in the Southeastern Massachusetts Health Study in Europe. There are three major points the Panel made which can summarized: 1. No excess of leukemia was found around Pilgrim Station. 2. The Southeastern Massachusetts Health Study over-predicted by a factor of 90 the number of leukemia cases attributable to plant operation. 3. The Southeastern Massachusetts Health Study failed to account for exposure to natural background radiation, which represents far larger biological exposure than plant Operation. Given All Of This, One Might Ask Why Didn't Common Sense Prevail In The Beginning? One Answer Might Be The Energy Of The Media In Pursuing The Story And Playing It Up No Matter What. Another Answer Might Be That The Original Study Purported To Show 'What Everyone Knows'. No One Really Stopped To Question Whether The Study Was Politically Motivated, Given That The Division of Environmental Health's Budget Had Been Cut.

  3. Case study: Massachusetts Department of Public Health's Southeastern Massachusetts health study on leukemia around Pilgrim Nuclear Power Station: Who won?

    International Nuclear Information System (INIS)

    Flanagan, Anita

    1993-01-01

    In October 1990, the Massachusetts Department of Public Health released their Southeastern Massachusetts health study. This is a study of leukemia incidence in 22 towns around Pilgrim NPP, for the period 1978 through 1986. Pilgrim Station had been returned to operation following a 3 year outage, from 1986-1989. During this period, some $300 million in capital outlay was invested by Boston Edison in upgrading safety systems and installing the so-Called Three Mile Island upgrades. A copy of the peer review panel report is attached to this paper. Because of the interest in the Southeastern Massachusetts Health Study in Europe. There are three major points the Panel made which can summarized: 1. No excess of leukemia was found around Pilgrim Station. 2. The Southeastern Massachusetts Health Study over-predicted by a factor of 90 the number of leukemia cases attributable to plant operation. 3. The Southeastern Massachusetts Health Study failed to account for exposure to natural background radiation, which represents far larger biological exposure than plant Operation. Given All Of This, One Might Ask Why Didn't Common Sense Prevail In The Beginning? One Answer Might Be The Energy Of The Media In Pursuing The Story And Playing It Up No Matter What. Another Answer Might Be That The Original Study Purported To Show 'What Everyone Knows'. No One Really Stopped To Question Whether The Study Was Politically Motivated, Given That The Division of Environmental Health's Budget Had Been Cut

  4. Teater vajab ellujäämiseks värsket dramaturgiat / Jane Rasch ; vahendanud Eva-Liisa Linder

    Index Scriptorium Estoniae

    Rasch, Jane

    2009-01-01

    Taani teatriteadlane Jane Rasch õpetas 10.-14. augustini 2009 Viljandi Kultuuriakadeemias toimunud draamakirjutuskursusel "Ideedest näidendi stsenaariumini". Ka näitekirjanike koolitamisest Taanis jt. Põhjamaades

  5. Readings on Jane Austen. The Greenhaven Press Literary Companion to British Authors.

    Science.gov (United States)

    Swisher, Clarice, Ed.

    Designed for young adults, this book on Jane Austen's novels is one of an anthology series providing accessible resources for students researching great literary lives and works. Contributing writers' essays in the book are taken from a wide variety of sources and are edited to accommodate the reading and comprehension levels of young adults; each…

  6. La métaphore entre sémantique et ontologie. La réception de la philosophie analytique du langage dans l'herméneutique de Paul Ricœur

    Directory of Open Access Journals (Sweden)

    Jean-Marc Tétaz

    2014-07-01

    Full Text Available  AbstractThe favourable reception of the analytic philosophy of language plays a central role in the composition of Ricœur’s literary hermeneutics. Following a brief description of the historical and methodological context of this reception, we show how Ricœur intends to link up phenomenology and analytic philosophy of language. Then we examine the role allocated to the analytic philosophy of language in establishing the idea of metaphor as a “more fundamental mode of reference” in The Rule of Metaphor. But once again Ricœur situates this semantic interpretation of metaphor within the context of an ontology. The result is methodological difficulties that mark the limits of Ricœur’s reception of the analytic philosophy of language.Keywords: Semantics, Metaphor, Ontology, Structuralism, Poetics.RésuméLa réception de la philosophie analytique du langage joue un rôle central dans la constitution de l’herméneutique littéraire de Ricœur. Après avoir tracé le cadre historique et systématique dans lequel s’inscrit cette réception, on montre comment Ricœur se propose d’articuler phénoménologie et philosophie analytique du langage. On étudie ensuite le rôle assigné à la philosophie analytique du langage pour la mise en place de la conception de la métaphore comme “mode plus fondamental de la référence” dans La métaphore vive. Mais Ricœur situe encore une fois cette interprétation sémantique de la métaphore dans un cadre ontologique. Il en résulte des difficultés systématiques qui marquent les limites de la réception de la philosophie analytique du langage par Ricœur.Mots-clés: Sémantique, Métaphore, Ontologie, Structuralisme, Poétique.

  7. [Rethinking ethics with Paul Ricœur. Nursing: between responsibility, care and justice].

    Science.gov (United States)

    Svandra, Philippe

    2016-03-01

    In this article, the purpose is less praising Paul Ricoeur's work than enlightening how the reader may actually find some practical, even operative help in this philosophical thought. This is particularly true regarding the fields of medicine and care. Paul Ricœur is now worldwide renowned as a major philosophical figure of the 20th century, and with books such as "Oneself as another", he occupies a very peculiar place at the crossroads of phenomenology and hermeneutics. Through both these philosophical traditions, Paul Ricœur offers some narrative ethics which may greatly sustain caregivers in their reflexion. Yet, the aim of this article is to focus on this philosopher who invites us to inhabit and play a role in this world. The goal is also to bring out the pragmatic ethics that this thinker developed, based on Aristotelian and Kantian traditions. Then, this piece seeks to demonstrate how the three stages of Ricoeur's "petite éthique" (his "small ethics"), which are the self's aim "for the good life with and for others in just institutions" can shed some light on the ethical consideration of politicals and caregivers.

  8. L’identità narrativa ricœuriana alla prova del «nouveau roman» di Robbe-Grillet

    Directory of Open Access Journals (Sweden)

    Alberto Romele

    2013-12-01

    Full Text Available The present essay aims to connect Ricœur’s notion of narrative identity – developed between the 1980s and 1990s – with the nouveau roman theorized by Alain Robbe-Grillet in writings published between 1956 and 1963 and then collected in Pour un noveau roman. In the first part, the essay will summarize Ricœur’s  Aristotelian –apocalyptic narratology model in the light of a comparison with the work of Frank Kermode. In the second part, noveau roman’s ontic realism will be presented. Finally, in the third part, starting with a comparison with the world of computer games, the essay will trace the effect of the overlapping of noveau roman with narrative identity both on the level of description and prescription.

  9. ERNEST J. GAINES’S MISS JANE PITTMAN: A SYMBOL OF THE BLACK FEMALE ABOLITIONIST STRUGGLE / « MADEMOISELLE JANE PITTMAN » D'ERNEST J. GAINES: UN SYMBOLE DE LA LUTTE ABOLITIONNISTE MENÉE PAR LES FEMMES DE COULEUR / "DOMNIŞOARA JANE PITTMAN” DE ERNEST J. GAINES: SIMBOL AL LUPTEI ABOLIŢIONISTE DUSE DE FEMEILE DE CULOARE

    Directory of Open Access Journals (Sweden)

    Ettien Yapo

    2014-11-01

    Full Text Available The Autobiography of Miss Jane Pittman by Ernest J. Gaines is a testimony of the black female abolitionist struggle. Its protagonist, Miss Jane Pittman, whose life covers the Civil War period (1861-1865 and the 1960s, embodies the African American women’s experience through her own story. As Ernest J. Gaines gives her the voice to relate her life experience, she reflects on her being and at the same time, she constructs her identity which reveals her heroism. Her struggle for freedom turns around her participation in the Civil War and the Civil Rights Movement. But her attempt to reach the North after the Civil War remains an important fact of her struggle. As a symbol of the black female abolitionist struggle, her “autobiography” is the voiceless African American women’s point of view.

  10. Catering for Pilgrims: Petrographic Analysis of Late Antique Kitchenware from the Monastery of St Lot at Deir 'Ain 'Abata, Jordan

    Directory of Open Access Journals (Sweden)

    Louise Joyner

    2000-10-01

    Full Text Available Petrography has been used to elucidate patterns of production and consumption of kitchenware at a typical Early Christian desert monastery on the Pilgrim route. While some vessels may have been produced locally, there is evidence for long distance trade of other vessels.

  11. Le premier écrit philosophique de Paul Ricœur: Méthode réflexive appliquée au problème de Dieu chez Lachelier et Lagneau

    Directory of Open Access Journals (Sweden)

    Marc-Antoine Vallée

    2012-06-01

    Full Text Available This paper proposes a presentation and an analysis of the first philosophical writing of Paul Ricœur, on the problem of God in the reflexive philosophies of Lachelier and Lagneau. His principal aim is to situate this first writing in the context of Ricœur’s philosophical work, by underlining his belonging to the french reflexive tradition and his refusing of the absolute idealism of Lachelier and Lagneau. The author insists more precisely on the realistic and personalist thesis of the young Ricœur and on the appearance of the problem of evil in his work.  

  12. The Distribution and Frequency of the Terms "Pride" and "Prejudice" in Jane Austen's Pride and Prejudice

    Directory of Open Access Journals (Sweden)

    Tanja Dromnes

    2009-03-01

    Full Text Available In this article we examine the title terms of Jane Austen's Pride and Prejudice (1813 with particular attention to their distribution and frequency in the text. Our method is to connect the statistical material gathered on frequency and distribution to a narratological analysis of the terms, with special emphasis on whether they occur within the focalization of the external narrator, or that of character-focalizers. In order to approach this task, we have availed ourselves of the narratological theories of Mieke Bal. We conclude that there is a differentiation among types of focalization in the novel that enhances the thematic structure of match-making. Although Jane Austen wrote and published her major works two centuries ago, they continue to fascinate literary scholars and general readers alike.

  13. D’une convergence remarquable entre phénoménologie et philosophie analytique: la lecture ricœurienne des thèses de Sartre et Ryle sur l’imagination

    Directory of Open Access Journals (Sweden)

    Jean-Luc Amalric

    2014-07-01

    Full Text Available The aim of this article is to analyse the meaning and the implications of the comparative interpretation of Sartre’s and Ryle’s theses on imagination that Ricœur undertook in the still unpublished text of his Lectures on Imagination. These lectures were delivered at the University of Chicago in 1975. First, the article shows how Ricœur brings out a strong convergence, both in the method and in the presuppositions, of the Sartrean and Rylean conceptions of imagination : the choice of a descriptive method leads the two philosophers to a common critique of the mental image. Secondly, the article analyses the properly critical side of the Ricœurian interpretation by showing how it eventually brings to light the common theoretical limitation of Sartre’s and Ryle’s theses on imagination. According to Ricœur, those theses lead to a conception of image as picture and fail to consider the image as fiction, and so they remain locked in a theory of reproductive imagination and of the primacy of perception.RésuméCet article se propose d’analyser le sens et les enjeux de la lecture croisée des thèses de Sartre et Ryle sur l’imagination à laquelle se livre Ricœur dans le texte encore inédit des Lectures on imagination professées en 1975 à l’Université de Chicago. Dans un premier temps, il montre comment Ricœur met en relief une convergence forte, de méthode et de présupposés entre les conceptions sartrienne et rylienne de l’imagination : le choix d’une méthode  descriptive conduisant les deux philosophes à une commune critique de l’image mentale. Puis, dans un second temps, il analyse le versant proprement critique de la lecture ricœurienne en montrant comment elle en vient à dénoncer une commune limitation théorique des thèses de Sartre et Ryle sur l’imagination. Selon Ricœur, ces thèses débouchent sur une conception de l’image comme tableau qui échoue à penser l’image comme fiction et elles restent

  14. Ambivalence and Ambiguity in The Autobiography of Miss Jane Pittman

    Directory of Open Access Journals (Sweden)

    Monica Michlin

    2006-05-01

    Full Text Available This close reading of the text highlights how Miss Jane, in her double role as protagonist and narrator, shows considerable ambivalence towards friend and foe alike, with the result that the apparently transparent ideological meaning of entire episodes is blurred by what some critics have merely put down to “conservatism.” I examine Miss Jane’s almost constant suppression of emotion, and frequent displays of ambivalence towards other black people; her ambiguous relationship to oppressive, but familiar whites like Albert Cluveau or Robert Samson; and her conflicted relation to black heroes and heroics. Is the leading character a variation on the “mammy” who has internalized racist figures of speech, and uses contradictory images that undermine black heroics and validate white oppression? Or is Gaines’s point to undo the “retrick” of heroics and of alienation alike, and, against of backdrop of constant, ordinary destruction of black lives, to cast the adult Miss Jane as a Brer Rabbit-like figure, for whom survival and resistance are both dialectically connected and opposed? Is there a contradiction between her “progress” towards resistance shown in the last section, and her metadiscursive comments in the present, and does her literally walking out of her own story give a conclusive meaning to her narrative, or does it point to the author’s not having been able to resolve the ambivalence and ambiguities within the text?

  15. Caught Up In Between Doublets: Neo-Victorian (TransPositions of Victorian Femininities and Masculinities in Jane Eyre and Rebecca Entre les doublets : (transpositions néo-victoriennes des figures victoriennes de la féminité et de la masculinité dans Jane Eyre et Rebecca

    Directory of Open Access Journals (Sweden)

    Marta Miquel-Baldellou

    2009-07-01

    Full Text Available En se départissant de la dichotomie victorienne manichéenne de l’ange du foyer et de la femme déchue pour éclairer les personnages de Jane et Bertha dans leur ouvrage pionnier The Madwoman in the Attic, Sandra Gilbert et Susan Gubar étudièrent la première épouse de Rochester, folle, comme le double subversif de Jane, faisant ainsi de Jane et de Bertha les facettes d’un seul et même personnage. Malgré le rejet moderniste des excès supposés de l’ère victorienne, Rebecca de Daphne du Maurier exploite une intrigue triangulaire similaire qui réinterprète et recrée Rochester, Bertha et Jane à travers Maxime de Winter, Rebecca et Mrs de Winter. Les conceptions victoriennes des féminités doubles, des doublets féminins pour ainsi dire, sont perpétuées et réactualisées à travers les textualités néo-victoriennes. Néanmoins, peut-on vraiment voir dans Bertha un personnage que Rochester tente d’assagir par l’entremise de la figure de l’ange du foyer, plutôt qu’un archétype de la femme déchue ? Jane n’est-elle pas destinée à découvrir le secret de Rochester avant de l’épouser ? Mrs de Winter a-t-elle à ce point le sens du sacré qu’elle ne cherche pas à entrer en concurrence avec Rebecca ? Rebecca est-elle à ce point élégante et infaillible qu’elle parvient à ne pas s’attirer le mépris de Maxime ? Cet article se propose d’examiner comment les héroïnes sont investies en termes de rôles sexuels dans l’écriture néo-victorienne – comment les rôles de l’ange du foyer et de la femme déchue dans Jane Eyre sont perpétués et subvertis à travers Rebecca en tant que texte moderne – et d’identifier et d’étudier les perceptions masculines victoriennes et néo-victoriennes.

  16. JANE, A new information retrieval system for the Radiation Shielding Information Center

    International Nuclear Information System (INIS)

    Trubey, D.K.

    1991-05-01

    A new information storage and retrieval system has been developed for the Radiation Shielding Information Center (RSIC) at Oak Ridge National Laboratory to replace mainframe systems that have become obsolete. The database contains citations and abstracts of literature which were selected by RSIC analysts and indexed with terms from a controlled vocabulary. The database, begun in 1963, has been maintained continuously since that time. The new system, called JANE, incorporates automatic indexing techniques and on-line retrieval using the RSIC Data General Eclipse MV/4000 minicomputer, Automatic indexing and retrieval techniques based on fuzzy-set theory allow the presentation of results in order of Retrieval Status Value. The fuzzy-set membership function depends on term frequency in the titles and abstracts and on Term Discrimination Values which indicate the resolving power of the individual terms. These values are determined by the Cover Coefficient method. The use of a commercial database base to store and retrieve the indexing information permits rapid retrieval of the stored documents. Comparisons of the new and presently-used systems for actual searches of the literature indicate that it is practical to replace the mainframe systems with a minicomputer system similar to the present version of JANE. 18 refs., 10 figs

  17. Morbidity and mortality amongst Indian Hajj pilgrims: A 3-year experience of Indian Hajj medical mission in mass-gathering medicine

    Directory of Open Access Journals (Sweden)

    Inam D. Khan

    2018-03-01

    Full Text Available The Hajj, a mass-gathering of over 3.5-million pilgrims, faces challenges to global health-security, housing, food, water, transportation, communication, sanitation, crowd-control and security. The Indian Medical Mission extended health-security to approximately 140,000 pilgrims, through outreach medical teams, primary-care clinics, tent-clinics, secondary-care hospitals and evacuation capabilities. Data on medical attendance, bed-occupancy, investigations, referrals, medication usage and deaths was compared. Outpatient attendance was 374,475 in static-clinics, 5135 in tent-clinics and 13,473 through task-forces. 585 (62.90% in-patients were hospitalized amongst 930 secondary-care referrals. Secondary-care bed-days were 2106 with average bed-occupancy being 77.78%. 495 patients were institutionalized in tertiary-care Saudi-Arabian hospitals. Infectious diseases were most commonly (53.26% encountered due to overwhelming respiratory-infections, followed by trauma (24.40%. Analgesics (66.38/100 patients and antibacterials (48.34/100 patients were frequently prescribed. Crude mortality amongst Indian pilgrims was 11.99/10,000. Risk-factors associated with high morbidity were old-age and pre-existing comorbidities. Overwhelming surge of patients facilitates transmission of communicable infections and leads to stress induced physical, mental and compassion fatigue amongst healthcare personnel. Respiratory infections are highly prevalent and easily transmissible during Hajj leading to significant morbidity, increased burden to existing health facilities, overwhelming costs on health systems and globalization of multiresistant pathogens. Diabetic patients should avoid heat exposure and use protective footwear during Hajj rituals. Mass-gathering medicine at Hajj can be optimized by improving patient knowledge on performing Hajj at a younger age, medicine compliance, avoiding self-medication, self-monitoring of hypertension, blood glucose, and preventive

  18. Morbidity and mortality amongst Indian Hajj pilgrims: A 3-year experience of Indian Hajj medical mission in mass-gathering medicine.

    Science.gov (United States)

    Khan, Inam D; Khan, Shahbaz A; Asima, Bushra; Hussaini, Syed B; Zakiuddin, M; Faisal, F A

    The Hajj, a mass-gathering of over 3.5-million pilgrims, faces challenges to global health-security, housing, food, water, transportation, communication, sanitation, crowd-control and security. The Indian Medical Mission extended health-security to approximately 140,000 pilgrims, through outreach medical teams, primary-care clinics, tent-clinics, secondary-care hospitals and evacuation capabilities. Data on medical attendance, bed-occupancy, investigations, referrals, medication usage and deaths was compared. Outpatient attendance was 374,475 in static-clinics, 5135 in tent-clinics and 13,473 through task-forces. 585 (62.90%) in-patients were hospitalized amongst 930 secondary-care referrals. Secondary-care bed-days were 2106 with average bed-occupancy being 77.78%. 495 patients were institutionalized in tertiary-care Saudi-Arabian hospitals. Infectious diseases were most commonly (53.26%) encountered due to overwhelming respiratory-infections, followed by trauma (24.40%). Analgesics (66.38/100 patients) and antibacterials (48.34/100 patients) were frequently prescribed. Crude mortality amongst Indian pilgrims was 11.99/10,000. Risk-factors associated with high morbidity were old-age and pre-existing comorbidities. Overwhelming surge of patients facilitates transmission of communicable infections and leads to stress induced physical, mental and compassion fatigue amongst healthcare personnel. Respiratory infections are highly prevalent and easily transmissible during Hajj leading to significant morbidity, increased burden to existing health facilities, overwhelming costs on health systems and globalization of multiresistant pathogens. Diabetic patients should avoid heat exposure and use protective footwear during Hajj rituals. Mass-gathering medicine at Hajj can be optimized by improving patient knowledge on performing Hajj at a younger age, medicine compliance, avoiding self-medication, self-monitoring of hypertension, blood glucose, and preventive health measures

  19. J. M. Gratale on Jane Chapman’s Issues in Contemporary Documentary

    Directory of Open Access Journals (Sweden)

    2010-03-01

    Full Text Available Jane Chapman, Issues in Contemporary Documentary.  Polity Press, 2009.  pp.  210 ISBN:  978-0-7456-4009-9.The prevalence of images in contemporary society and culture is a patent reality.  From digital photography to cinematic film, and cell phone imaging to You Tube, the production and circulation of the image is becoming more and more diffused. In conjunction with such developments is the fact that the mediums and technologies which ‘deliver’ these images are constantly diversifying and imp...

  20. La felicidad como represión: orden y desorden en Jane Eyre y El vasto mar de los Sargazos

    Directory of Open Access Journals (Sweden)

    Mónica Roesel

    2014-01-01

    Full Text Available Este ensayo traza las historias de Jane Eyre, protagonista de la novela homónima (Charlotte Brontë 1847, y Antoinette Cosway, protagonista de El vasto mar de los Sargazos (Jean Rhys 1966. Son historias paralelas de abandono y búsquedas fallidas que convergen en un punto: Edward Rochester. Se sugiere que el final feliz de Jane y el final trágico de Antoinette están determinados por la imposibilidad del etos victoriano, encarnado en Rochester, de aceptar el caos: el desorden que representa Antoinette —desorden de la alteridad— debe ser sometido. La represión, entonces, aparece como única posibilidad de existencia. This essay traces the stories of Jane Eyre, the heroine of the homonymous novel (Charlotte Brontë, 1847, and Antoinette Cosway, the heroine of Wide Sargasso Sea (Jean Rhys, 1966. These parallel stories of abandonment and failed searches converge in one point: Edward Rochester. It is suggested that Jane’s happy ending and Antoinette’s tragic ending are both determined by the impossibility of the Victorian ethos, personified in Rochester, to accept chaos: the disorder represented by Antoinette —disorder of alterity— must be tamed. Repression, then, appears as the sole possibility of existence.

  1. The Anonymous Jane Austen: Duelling Canons

    Directory of Open Access Journals (Sweden)

    Edward Copeland

    2017-12-01

    Full Text Available This essay initially addresses some theoretical concepts such as adaptation and appropriation. I intend to analyze how Jane Austen herself indulged in her own appropriations from the woman’s canon, in particular through a story entitled Guilt Pursued by Conscience, a tale she found in the “Lady’s Magazine” of 1802. I will show that this tale that claimed Austen’s particular attention was re-appropriated in Emma (although in the broadest sense of parody and, to a lesser extent, in Sense and Sensibility. The second part of the essay, instead, will move on to analyze how novelists of the generation that followed Austen felt free to import dialogue, characters, and plots from Austen’s works, showing no obligation to their source, just as she had done with the “Lady’s” tale. I will mention and comment on a series of novels, especially from the silver fork school, that draw from Austen’s plot, characters and happenings without acknowledging their legacy to their predecessor.

  2. The Exploration of human experience in Jane Austen's Northanger Abbey

    OpenAIRE

    Mulas, Francesco Gesuino

    2005-01-01

    Jane Austen's purpose in Northanger Abbey, both in her aesthetic principles and moral intents, is to explore the human experience in its fullest sense. How do people perceive and understand themselves and each other? What are they like and how can they learn and grow? If moral problems are a question of thought rather than of action, as a consequence to ask what characters are like is also to ask what an author's conception of them should be.

  3. Il romanzo moderno nella poetica del sé di Paul Ricœur

    Directory of Open Access Journals (Sweden)

    Roberto Talamo

    2013-12-01

    Full Text Available La riflessione sul romanzo moderno e la nascita di uno dei concetti più importanti dell’ermeneutica del sé, quello di «identità narrativa», sono strettamente intrecciati nel pensiero di Ricœur. Attraverso una lettura di diverse opere del filosofo francese, si mostrerà il percorso di genesi poetica di questo concetto, confrontando altresì la teorizzazione ricoeuriana a proposito del romanzo moderno con le principali acquisizioni su questa forma letteraria da parte della critica e della teoria della letteratura.

  4. Kontoririietus võiks säilitada inimese isikupära / Kristina Herodes, Lana Vallo, Janeli Salumets ; intervjueerinud Mirjam Simmer

    Index Scriptorium Estoniae

    Herodes, Kristina, 1976-

    2011-01-01

    Tallinna Kaubamaja loovjuhti Kristina Herodese, jumestuskunstniku Lana Vallo ja Goldwelli turundusjuhi Janeli Salumetsa soovitusi kontoritöötajate ja töövestlusele minejate rõivastuse, jumestuse ja soengute osas

  5. THE INFLUENCE OF SOCIAL STATUS AND SOLIDARITY TO THE QUANTITY OF UTTERANCES IN JANE AUSTEN’S NOVELS

    Directory of Open Access Journals (Sweden)

    Citra Suryanovika

    2018-03-01

    Fokus penelitian pada ujaran yang disampaikan oleh tokoh utama perempuan dalam enam novel Jane Austen. Penelitian bertujuan menelaah pengaruh status sosial dan solidaritas pada kuantitas ujaran. Hasil penelitian menunjukkan 1,738 dengan rincian 266 ujaran Elinor Dashwood, 368 ujaran Elizabeth Bennet, 194 ujaran Fanny Price, 473 ujaran Emma Woodhouse, 113 ujaran Anne Elliot, and 324 ujaran Catherine Morland. Berdasarkan peringkat, status sosial tinggi Emma Woodhouse menghasilkan jumlah ujaran paling banyak, dibandingkan dengan lima tokoh lainnya, namun Fanny Price dengan status sosial paling bawah berada di peringkat kelima dari enam tokoh yang ditelaah. Telaah keakraban menunjukkan 66,7% jumlah ujaran dengan skala solidaritas tinggi, dan 33,3% ujaran dengan skala solidaritas rendah. Berdasarkan hasil analisa, dapat disimpulkan bahwa penentu kuantitas ujaran bukan hanya ditentukan oleh status sosial dan solidaritas karakter, tapi juga ditentukan oleh ketertarikan dan rasa penasaran. Kata kunci: Status Sosial, Skala Solidaritas, Ujaran, Jane Austen.

  6. Ricœur et la théorie de l’action

    Directory of Open Access Journals (Sweden)

    Jean-Luc Petit

    2014-07-01

    Full Text Available  AbstractRicoeur’s Philosophy of the Will is reexamined here both as a source of motivation for his project of dialoguing with the analytic theory of action and as an explanation for the lack of response on the part of his Anglo-American interlocutors.Keywords: Actions, Language, Body, Idealism. RésuméLa Philosophie de la volonté de Ricœur est revisitée ici comme source de motivation de son entreprise de dialogue avec la théorie analytique de l’action et comme explication du défaut de réponse de ses interlocuteurs anglo-américains.Mots-clés: Actions, Langage, Corps, Idéalisme.

  7. L’image du père et du jardin : Jane Eyre de Charlotte Brontë  et WideSargasso Sea de Jean Rhys Of Father Figures and Gardens: Charlotte Brontë’s Jane Eyre and Jean Rhys’s Wide Sargasso Sea

    Directory of Open Access Journals (Sweden)

    Anne-Marie Baranowski

    2009-10-01

    Full Text Available Though no father actually appears as a character either in Jane Eyre or in Wide Sargasso Sea, the father figure looms large in both novels, as a complex, protean and paradoxical entity, playing a crucial part in the fate of the protagonists. Jane Eyre and Antoinette Cosway are orphaned at an early age, Rochester’s father is depicted as remote and insensitive; the surrogate fathers —Antoinette’s stepfather, Jane’s uncles— mostly fail when they try to replace the missing one. Rochester himself is an ambiguous character who appears in both novels as a son, lover and husband on the one side, as a father figure on the other. In Wide Sargasso Sea he acquires through his marriage to the heiress Antoinette Cosway a legal authority which he eventually uses to destroy his wife; in Jane Eyre he first appears as the wealthier, more knowledgeable, stronger character before he discovers a female counterpart who does more than merely hold her ground.These different aspects of the father figure are closely linked to the motif of the garden which mirrors the inner development of the —mostly— female characters. It is not entirely similar to nature itself, though it is part of it; the latter means in both novels lethal dangers and elemental violence, whereas the garden is a sheltered place. In Wide Sargasso Sea, the debased garden of Coulibri simultaneously conveys a distorted, though by no means untrue reflection of the father figure and a sanctuary from the harshness of the outside world. It also means a place of peace and of simple joys for Jane Eyre, making up for the deprived life at the Lowood boarding school; but contrasting with Coulibri it does not preclude the contact with the outside world which she actually longs for. Hence the garden mirrors the crucial moments and experiences in the lives of both heroines, including love, married life and loss.

  8. Jane Austen's Novels as a Guide to Social and Individual Responsibility for High School Students.

    Science.gov (United States)

    Fritzer, Penelope

    1998-01-01

    Jane Austen's novels are particularly appropriate for adolescents. These classics deal with topics of high interest to young people. Austen grapples with the question of what the individual owes to society and what he or she is obliged to tolerate in the way of strictures on behavior. Article proposes that Austen's novels should be more widely…

  9. The Mystery of the Past Haunts Again: Jane Eyre and Eugenie Marlitt’s Die zweite Frau Le mystère du passé hante encore: l’influence de Jane Eyre sur Die zweite Frau d’Eugenie Marlitt

    Directory of Open Access Journals (Sweden)

    Ivonne Defant

    2010-03-01

    Full Text Available Charlotte Brontë’s Jane Eyre is a classic in women’s fiction. When it was published in 1847, it made an immediate impact in mid-Victorian England, partly because it drew on the paradigmatic story of a romance heroine, partly because it interpreted the needs of the women of the time. Since then, the Thornfield Hall attic where Bertha Mason is kept hidden by the master of the house, Mr. Rochester, has become the metaphor of a feminine place of imprisonment and,at the same time, of rebellion against patriarchal rules.About thirty years after Jane Eyre, another woman writer published a book which evokes the haunting atmosphere of the Thornfield Hall theme, i.e., the German writer Eugenie Marlitt, the author of Die zweite Frau ( The second wife, 1874.Interestingly, Marlitt seems to recapture, while rewriting it, the character of Bertha within the context of German domestic fiction. Bothnovels explore indeed the issue of the imprisoned and socially marginalised woman in terms of ethnicity to show how gender roles are inevitably complicit with power relations. In Jane Eyre and Die zweite Frau the house motif is a pivotal element that leads to our understanding of the female characters, but it is above all the mystery that reverberates through the houses of the two novels, represented by two women, the Creole Bertha  and the Indian Lotusblume, which, being crucial to the articulation of the discursive thrust underlying the two narratives, discloses the multi-layered construction of femininity.Jane Eyre de Charlotte Brontë est un classique de la littérature féminine. Lors de sa publication en 1847, le roman eut un impact immédiat sur l’Angleterre victorienne, d’une part parce qu’il racontait l’histoire paradigmatique d’une héroïne de romance et d’autre part parce qu’il se faisait l’interprète des désirs des femmes de l’époque. Depuis, le grenier de Thornfield Hall où le maître de maison cache Bertha Mason, est devenu la

  10. Camønoen: A pilgrim trail conceived along a communitarian business model

    DEFF Research Database (Denmark)

    Meged, Jane Widtfeldt; Gyimóthy, Szilvia

    2017-01-01

    This paper presents an alternative experiment of building an operative communitarian business model to leverage tourism in Southern Denmark. Coastal communities in Denmark have experienced a steady socioeconomic decline, which has further been aggravated by a stagnating tourism and agricultural...... sector. Within this context, coastal regions are attempting to harness the potentials of the emerging collaborative economy by experimenting with communitarian business models. Such is the case of a digitally facilitated pilgrim trail in Denmark, the Camøno, which was conceived in 2016 to mobilize sparse...... and loosely connected local resources to create value for tourists and citizens. The trail sustains over 200 small local actors and attracted over 75.000 visitors after less than a year of operation. Our paper explores the rapid success and consolidation of the Camøno trail by analyzing the performativity...

  11. Jane Eyre Character Analysis from Feminism Perspective%女性主义视角下的《简·爱》性格分析

    Institute of Scientific and Technical Information of China (English)

    陈敬梅

    2014-01-01

    《简·爱》是十九世纪英国著名的女作家夏洛蒂·勃朗特的代表作。书中塑造了一位极具性格魅力的女性形象--简·爱。本文旨从她反抗社会的不公、追求自由、平等的爱情以及追求人格独立、维护自己尊严这三个展现其女性意识的角度来探讨简·爱的性格魅力。%"Jane o Eyre"is a famous nineteenth-century British women writers Charlotte Bronte's masterpiece. The book shaped a very charismatic image of women-Jane oEyre. This paper aims to fight social injustice in her pursuit of freedom, equality and the pursuit of personal independence love, these three safeguard their dignity and perspective to show its women sense to explore the charismatic of Jane oEyre.

  12. Literary Cross-dressing: Jane Addams Finds her Voice in Democracy and Social Ethics

    OpenAIRE

    Joslin, Katherine

    2018-01-01

    In 1881 Jane Addams dressed herself, rhetorically speaking, as Cassandra to dramatize the fate of the first generation of American women to graduate from college. Standing before her classmates at Rockford Female Seminary, she cast the new woman as the mythic Greek heroine: «The frail girl stood conscious of Truth but she had no logic to convince the impatient defeated warriors, and no facts to gain their confidence, she could only assert and proclaim until at last in sooth she becomes mad.» ...

  13. At Home with Jane Austen: Imagining the Colonial Connection in Mansfield Park

    Directory of Open Access Journals (Sweden)

    Blanka Grzegorczyk

    2009-11-01

    Full Text Available This article examines Jane Austen's Mansfield Park in the context of the complex relationship between imaginative literature and the experience of empire. Specifically, it argues that the way Austen's novel plays with the imperial experience is more ambivalent than many critics have indicated. It suggests that underlying the imaginative conceptualization of the relations between metropole and colony are certain evasions and contradictions in which the novel consciously abounds. A close reading of the novel demonstrates how issues related to metropole and colony may be articulated within the literary mainstream, and why such narrative articulation is important.

  14. Jane Kelsey, Serving Whose Interests? The Political Economy of Trade in Services Agreements

    Directory of Open Access Journals (Sweden)

    Maureen Irish

    2009-02-01

    Full Text Available Serving Whose Interests is an examination of the General Agreement on Trade in Services [GATS] since its inception in 1995, with several case studies that discuss services trade in specific applications around the world. The scholarship i s extensive and detailed. Jane Kelsey, law professor at the University of Auckland, has criticized the pro-market services trade regime i n her role as a political activist. In this book, her goals are to make the technicalities of trade rules accessible and to show their effects on people and communities.

  15. Pilgrims sailing the Titanic: plausibility effects on memory for misinformation.

    Science.gov (United States)

    Hinze, Scott R; Slaten, Daniel G; Horton, William S; Jenkins, Ryan; Rapp, David N

    2014-02-01

    People rely on information they read even when it is inaccurate (Marsh, Meade, & Roediger, Journal of Memory and Language 49:519-536, 2003), but how ubiquitous is this phenomenon? In two experiments, we investigated whether this tendency to encode and rely on inaccuracies from text might be influenced by the plausibility of misinformation. In Experiment 1, we presented stories containing inaccurate plausible statements (e.g., "The Pilgrims' ship was the Godspeed"), inaccurate implausible statements (e.g., . . . the Titanic), or accurate statements (e.g., . . . the Mayflower). On a subsequent test of general knowledge, participants relied significantly less on implausible than on plausible inaccuracies from the texts but continued to rely on accurate information. In Experiment 2, we replicated these results with the addition of a think-aloud procedure to elicit information about readers' noticing and evaluative processes for plausible and implausible misinformation. Participants indicated more skepticism and less acceptance of implausible than of plausible inaccuracies. In contrast, they often failed to notice, completely ignored, and at times even explicitly accepted the misinformation provided by plausible lures. These results offer insight into the conditions under which reliance on inaccurate information occurs and suggest potential mechanisms that may underlie reported misinformation effects.

  16. Technical evaluation report on the monitoring of electric power to the reactor-protection system for the Pilgrim Nuclear Power Station

    International Nuclear Information System (INIS)

    Selan, J.C.

    1982-01-01

    This report documents the technical evaluation of the monitoring of electric power to the reactor protection system (RPS) at the Pilgrim Nuclear Power Station. The evaluation is to determine if the proposed design modification will protect the RPS from abnormal voltage and frequency conditions which could be supplied from the power supplies and will meet certain requirements set forth by the Nuclear Regulatory Commission. The proposed design modifications will protect the RPS from sustained abnormal voltage and frequency conditions from the supplying sources

  17. La costellazione dei generi: forme letterarie e modi del discorso nel pensiero di Paul Ricœur

    Directory of Open Access Journals (Sweden)

    Roberto Talamo

    2013-12-01

    Full Text Available Il pensiero filosofico di Ricœur si è sviluppato attraverso un costante e proficuo confronto con le diverse forme della letteratura antica e moderna. Con una carrellata attraverso i testi del filosofo e quelli dei principali interpreti della sua riflessione, si ricostruisce la trama significativa dei nessi tra filosofia e generi letterari: questi offrono al pensiero ricoeuriano la possibilità di «pensare di più» i nodi etici del campo filosofico.

  18. Cause of Death in “John Doe & Jane Doe”: A 5 year review

    Science.gov (United States)

    Dasari, Harish; Singh, Amandeep

    2014-01-01

    Sometimes the opinion regarding the cause of death in “John Doe or Jane Doe” i.e. on unknown dead bodies is a test of ability of the forensic expert and on many occasions it yields little or no results. Here the identification of the body as such poses problems; rest aside the opinion regarding the cause/ manner of death. The present 5yr study was undertaken in the Department of Forensic Medicine & Toxicology, Government Medical College & Hospital, Chandigarh to find the patterns of cause of death in unknown dead bodies, as very little literature is available with regard to John Doe or Jane Doe cases as a group, in India. Unidentified bodies comprised 4 % of the total 3165 cases brought for post-mortem examination to the department. Maximum cases belonged to the age group 41 - 50 years, 30 %. Majority of the opinions regarding the cause of death were given as “no definite opinion” (31%), followed by “cranio-cerebral damage” (30 %) and coronary insufficiency/ Cardiac disease/ aortic aneurysm rupture, (8.9%). Following measures should be undertaken to increase the chances of getting these unknown bodies identified and thereby increasing the chances of arriving at a definite cause of death: drafting of additional legislation for the management of unidentified dead bodies along with streamlining of work on the part of police, use of active investigation and modern investigative techniques, fixing the accountability of the police. Internet based sites of the police like ZIPNET (Zonal Integrated Police Networking) in Northern India, should also be used. PMID:25302219

  19. The effect of radiation induced electrical conductivity (RIC) on the thermal conductivity

    International Nuclear Information System (INIS)

    White, D.P.

    1993-01-01

    Microwave heating of plasmas in fusion reactors requires the development of microwave windows through which the microwaves can pass without great losses. The degradation of the thermal conductivity of alumina in a radiation environment is an important consideration in reliability studies of these microwave windows. Several recent papers have addressed this question at higher temperatures and at low temperatures. The current paper extends the low temperature calculations to determine the effect of phonon-electron scattering on the thermal conductivity at 77 K due to RIC. These low temperature calculations are of interest because the successful application of high power (>1 MW) windows for electron cyclotron heating systems in fusion reactors will most likely require cryogenic cooling to take advantage of the low loss tangent and higher thermal conductivity of candidate window materials at these temperatures

  20. STRATEGI PEMASARAN PAKET WISATA PILGRIM PT. DONGAN SAHUTA TOUR AND TRAVEL DI BALI

    Directory of Open Access Journals (Sweden)

    Paradita Putri Amelia

    2017-04-01

    Full Text Available This study aimed to determine the marketing activities of pilgrim package tour that have been performed by PT. Dongan Sahuta Tour and Travel, develop strategies and also marketing programs that can be implemented by the company. Data collection by observation, interviews, questionnaires and literature study. The sampling technique used purposive sampling. Data were analyzed using qualitative descriptive analysis, analysis of the Likert scale and SWOT analysis approach. The results obtained there are four teen indicators of strengths, weaknesses of tree indicators, four indicators of opportunities and four indicators threats. Marketing strategies that can be implemented by the firm such as 1create and develop a quality product, 2provide rebates to customers who have used the services of PT. Dongan Sahuta Tour and Travel several times.The advice given are more active in the promotion by giving rebates, conduct marketing activities as E-commers, expand cooperation with business trips or individuals.

  1. Tornando-se Jane: a individuação retratada em filme

    Directory of Open Access Journals (Sweden)

    Luiza Bontempo e Silva

    2009-12-01

    Full Text Available Este é um trabalho de fundo explicativo que pretende estabelecer um diálogo entre o filme Becoming Jane (traduzido, no Brasil, como Amor e inocência, de Julian Jarrold, com a concepção junguiana de processo de individuação. Foi observado que o filme faz várias referências à obra de Jung, sendo a trama principal um exemplo (intencional ou não do conceito junguiano de processo de individuação. No filme analisado a personagem principal passa por um processo difícil de descobrimento de si mesma e de confronto com o senso comum, processo também vivido por muitos e essencial para a realização ou formação da personalidade.

  2. Engineering Evaluation and Assessment (EE and A) Report for the Symbolic and Sub-symbolic Robotics Intelligence Control System (SS-RICS)

    Science.gov (United States)

    2018-04-01

    ARL-TR-8352 ● APR 2018 US Army Research Laboratory Engineering Evaluation and Assessment (EE&A) Report for the Symbolic and Sub...APR 2018 US Army Research Laboratory Engineering Evaluation and Assessment (EE&A) Report for the Symbolic and Sub-symbolic Robotics...Intelligence Control System (SS-RICS) by Troy Dale Kelley and Eric Avery Human Research and Engineering Directorate, ARL Sean McGhee STG Inc

  3. Translation Collective and Illustration: aesthetic film creation from Jane Austen

    Directory of Open Access Journals (Sweden)

    Lemuel da Cruz Gandara

    2015-08-01

    Full Text Available http://dx.doi.org/10.5007/2175-7917.2015v20n2p67 From metonymic clippings of the novels Sense and Sensibility (1811, Pride and Prejudice (1813, Emma (1815 and Persuasion (1817, all written by the English author Jane Austen (1775-1817, we propose a comparative analysis among the literary texts, the illustrations by Hugh Thomson at the end of the nineteenth century and the film footage created between 1995 and 2005. Our goal is to confront tickets to find similarities and differences dialogic between them. This perspective reveals the interpretations made by many readers over the years and the receptions of the English writer in different contexts and media. Our critical and theoretical reflection is based on studies of the Russian philosopher Mikhail Bakhtin about the aesthetics of literary creation and amplifies the concepts of literary cinema, collective translation and aesthetics of film creation.

  4. Pride and prejudice and zombies: The classic Regency romance—Now with ultraviolent zombie mayhem!, by Jane Austen and Seth Grahame-Smith [book review

    Directory of Open Access Journals (Sweden)

    Craig B. Jacobsen

    2009-11-01

    Full Text Available Review of Jane Austen and Seth Grahame-Smith. Pride and prejudice and zombies: The classic Regency romance—Now with ultraviolent zombie mayhem! Philadelphia, PA: Quirk Books, 2009. $12.95 (320p ISBN 978-1594743344.

  5. La influencia de la Postmodernidad en Orgullo y Prejuicio (1813: Persiguiendo a Jane Austen (2008, Dan Zeff.

    Directory of Open Access Journals (Sweden)

    Irene Romero González

    2012-06-01

    Full Text Available Las novelas de Jane Austen siguen inspirando nuevos relatos cinematográficos pues éstos toman sus historias o sus personajes y los adaptan a contextos culturales y axiológicos actuales de gran diversidad. Es el caso de la novela de Orgullo y Prejuicio de la que se han realizado numerosas adaptaciones clásicas, así como que ha sido objeto de referencia en películas, en trabajos literarios y de adaptaciones postmodernas. Uno de estos trabajos postmodernos es Persiguiendo a Jane Austen una serie inglesa que nos adentra en el mundo de la Regencia a través de las vivencias de una mujer contemporánea que descubre una puerta que comunica ambos mundos y que le permite vivir la historia de Austen bajo la piel de Elizabeth Bennet. A lo largo de este trabajo se realizará un análisis comparado entre esta adaptación postmoderna y su referente literario para comprobar cómo influyen las ideas de la Postmodernidad en un clásico de la literatura decimonónica, pues es una tendencia que nos ayuda a replantearnos un periodo de la historia y a reinterpretar el contexto de la novela original a uno distinto y original.  

  6. Métaphores, paraboles et analogie: La référence à la théologie dans la pensée de Paul Ricœur

    Directory of Open Access Journals (Sweden)

    Gilbert Vincent

    2012-12-01

    Full Text Available Il est admis que l’étude de la métaphore représente une inflexion décisive dans l’herméneutique de Ricœur. On sait peut-être moins que cette étude est concomitante de celle de la parabole, qui représente une inflexion également notable dans la contribution ricœurienne à l’herméneutique biblique. Il arrive pourtant qu’on tire argument de cette concomitance pour prétendre que le transfert de certains présupposés théologiques (quant à la nature du langage et de la Vérité s’en trouve facilité, et l’on ne craint pas d’avancer que les pages consacrées à l’analogia entis, dans La métaphore vive, prouvent la prégnance d’intérêts théologiques douteux dans l’élaboration de la théorie de la métaphore. Pour contrer cette critique dévastatrice, nous nous appuierons sur certaines analyses d’Umberto Eco, qui impliquent que la question des rapports entre analogia entis et métaphore n’a rien d’épistémologiquement scandaleux, et sur celles d’Alain qui, voici un siècle, a esquissé une interprétation des paraboles très proche de celle de Ricœur.

  7. "Young ladies are delicate plants": Jane Austen and Greenhouse Romanticism.

    Science.gov (United States)

    Lynch, Deidre Shauna

    2010-01-01

    By annotating how in Mansfield Park and Northanger Abbey Jane Austen tracks between the novelist's domain and the naturalist's, this essay seeks to unsettle some entrenched assumptions about her relationship to realism—and the ideological work of naturalization that realism is said to sponsor—as well as to romanticism. Austen's era, which we customarily identify as the time of a romantic return to nature, was marked by conflicts over what nature did and did not include—conflicts between, in the parlance of the period, "the botanist" and "the florist," between an account of nature as that which was given and an account of nature as that which (as with the modern nurseryman's new hybrids and luxuriants) might be manufactured. In arranging for her young heroines' stories of growing up to unfold in the "artificial climates" of modern fashionable gardening and amidst "florists' flowers," Austen deliberately works through those conflicts. She inhabits the plot of "natural development" to which she is often linked in elusively oppositional ways.

  8. Creative (misreading? Paula Rego’s Jane Eyre Jane Eyre vue par Paula Rego : de l’art de la (mauvaise lecture créatrice

    Directory of Open Access Journals (Sweden)

    Laurent Bury

    2009-07-01

    Full Text Available En 2002, l’artiste britannique d’origine portugaise Paula Rego a créé une série de vingt-cinq lithographies inspirées par Jane Eyre. Ces œuvres ont connu une popularité immédiate, malgré leur interprétation peu orthodoxe du roman de Charlotte Brontë. Les gravures de Paula Rego ont ainsi pu être qualifiées d’ « anti-illustrations » ou de « méta-images », mais cet article les considère comme une forme graphique de « lecture créative », voire de « mauvaise lecture créative », puisque l’on pourrait soupçonner Paula Rego d’avoir délibérément « mal lu » le roman. Cependant, dans sa relation avec les textes antérieurs, Charlotte Brontë elle-même était adepte de la « mauvaise lecture », ou du moins aimait à induire le lecteur en erreur.

  9. Psychometric Properties of the Persian Version of the God Locus of Health Control (GLHC): A Study on Muslim Pilgrims.

    Science.gov (United States)

    Nabipour, Amir Reza; Nakhaee, Nouzar; Khanjani, Narges; Soltani, Maryam; Moradlou, Hossein Zirak; Soltani, Zahrasadat

    2018-02-01

    God Locus of Health Control (GHLC) scale is an instrument for assessing to what extent one believes that God controls his/her health or disease. The aim of this study was to describe the cultural adaptation of this scale and to investigate the psychometric properties of Persian version. At first, the scale was forward-translated to Persian, and then, backward-translation was conducted. Finally, the synthesized back-translated version was prepared and compared to the draft Persian-language version of the GLHC. In the next step, in order to test cognitive debriefing, the Persian-language version of the questionnaire was completed by 20 pilgrims. Final version of Persian GHLC scale was answered by 600 pilgrims attending religious holy places. Mean age of respondents was 33.15 (±11.04) years. There was a positive correlation between six items of GLHC scale and inter-item correlation coefficients. The Cronbach's alpha coefficient was 0.84. Exploratory factor analysis showed that the G LHC scale had a one-factor structure. The factor loadings for all items ranged from 0.57 to 0.77. Residual correlations of all items were between -0.2 and +0.2. The people with lower income had significantly higher score of GLHC scale. GLHC scale score had a significant positive correlation with DUREL subscale and MHLC Chance Externality subscale score. There was no a significant correlation between GLHC scale score and Multidimensional Health Locus of Control (MHLC) Internality and Powerful subscales scores. The results of the present study showed that the Persian version of GHLC scale has acceptable factorial validity and internal consistency reliability.

  10. Serial Austen. Mashingups with Zombies

    Directory of Open Access Journals (Sweden)

    Eleonora Federici

    2017-01-01

    Full Text Available Jane Austen sells. She sells in all possible ways, her novels have been adapted for the cinema and the stage, they have been rewritten as comics and graphic novels. Jane austen is a cultural icon. The interest in her life is so strong that many biographies have been written in order to recover new facts and details. The places where she has lived and the places depicted in her novels have become tourist sites for literary pilgrims. Austen is a cross-over phenomenon, with regency costume balls recreated in her name and an endless proliferation of her works in all media. My essay will investigate Jane Austen and Seth Grahame-Smith’s Pride and Prejudice and Zombies (2009, a mash-up novel which has become a real cultural phenomenon of the last decade and will demonstrate how it can be considered a serial narrative. If as Henry Jenkins asserts, seriality implies the unfolding of a story over time through a process of “chunking” (that is creating meaningful parts of the same story and of “dispersal” (that is breaking the story into more parts and in more genres and media, mash-ups seems to do this.  Austen’s story remains as a “story hook” which pushes the reader to come back to different products for a continuation of the same story. So, if on the one hand, seriality occurs within the same text, the story-telling of Austen’s stories across genres and media is part of a seriality process.

  11. Frédéric Hemmer: Serving a world-wide community

    CERN Multimedia

    2009-01-01

    CERN’s IT Department provides a variety of services to the Organization, its users and hundreds of institutes around the world. It plays a vital role in the operation of the LHC and its experiments. This week we meet the new IT Department Head, who tells us about the challenges his teams will face over the coming years. In this period leading up to the first data being produced at the LHC and processed via the Worldwide LHC Computing Grid (WLCG), the IT Department is focussing on service for users and the new Computing Centre which should be built on the Prévessin site. As Frédéric Hemmer, the new IT Department Head, explains, "we are here to serve CERN, its associated institutes and its industrial partners. The Grid is the best illustration of this, but we do have other informatics products that we share with a large number of users across the world, such as INDICO (conference management system) and INVENIO (archiving system used...

  12. Hyperspatial Thermal Imaging of Surface Hydrothermal Features at Pilgrim Hot Springs, Alaska using a small Unmanned Aerial System (sUAS)

    Science.gov (United States)

    Haselwimmer, C. E.; Wilson, R.; Upton, C.; Prakash, A.; Holdmann, G.; Walker, G.

    2013-12-01

    Thermal remote sensing provides a valuable tool for mapping and monitoring surface hydrothermal features associated with geothermal activity. The increasing availability of low-cost, small Unmanned Aerial Systems (sUAS) with integrated thermal imaging sensors offers a means to undertake very high spatial resolution (hyperspatial), quantitative thermal remote sensing of surface geothermal features in support of exploration and long-term monitoring efforts. Results from the deployment of a quadcopter sUAS equipped with a thermal camera over Pilgrim Hot Springs, Alaska for detailed mapping and heat flux estimation for hot springs, seeps, and thermal pools are presented. Hyperspatial thermal infrared imagery (4 cm pixels) was acquired over Pilgrim Hot Springs in July 2013 using a FLIR TAU 640 camera operating from an Aeryon Scout sUAS flying at an altitude of 40m. The registered and mosaicked thermal imagery is calibrated to surface temperature values using in-situ measurements of uniform blackbody tarps and the temperatures of geothermal and other surface pools acquired with a series of water temperature loggers. Interpretation of the pre-processed thermal imagery enables the delineation of hot springs, the extents of thermal pools, and the flow and mixing of individual geothermal outflow plumes with an unprecedented level of detail. Using the surface temperatures of thermal waters derived from the FLIR data and measured in-situ meteorological parameters the hot spring heat flux and outflow rate is calculated using a heat budget model for a subset of the thermal drainage. The heat flux/outflow rate estimates derived from the FLIR data are compared against in-situ measurements of the hot spring outflow rate recorded at the time of the thermal survey.

  13. Technical evaluation of the proposed design modifications and technical specification changes on grid voltage degradation (Part A) for the Pilgrim Nuclear Power Station, Unit 1

    International Nuclear Information System (INIS)

    White, R.L.

    1980-01-01

    This report documents the technical evaluation of the proposed design modifications and Technical Specification changes for protection of Class 1E equipment from grid voltage degradation for the Pilgrim Nuclear Power Station. The review criteria are based on several IEEE standards and the Code of Federal Regulations. The evaluation compares the submittals made by the licensee with the NRC staff positions and the review criteria and presents the reviewer's conclusion on the acceptability of the proposed system

  14. Sobre el realisme històric i el teatre-document (o de quan els autors estudiaven Història

    Directory of Open Access Journals (Sweden)

    Ramon X. Rosselló

    2000-03-01

    Full Text Available Resum: This essay attempts to approach the Catalan theatrical production of the 1960s and 70s related to the theatredocument, with special emphasis on M. Aurèlia Capmany and X. Romeu’s «Qüestions and answers about the Ufe and death of Francesc Layreu lawyerfor the workers of Catalonia» (1970, one of the most outstanding examples of this theatrical formula.Paraules clau: realisme històric; teatre-document; teatre català; anys seixanta i setanta; M. Aurèlia Campmany; Xavier Romeu

  15. Target development for 67Cu, 82Sr radionuclide production at the RIC-80 facility

    Science.gov (United States)

    Panteleev, V. N.; Barzakh, A. E.; Batist, L. Kh.; Fedorov, D. V.; Ivanov, V. S.; Krotov, S. A.; Molkanov, P. L.; Moroz, F. V.; Orlov, S. Yu.; Volkov, Yu. M.

    2018-01-01

    A high-current cyclotron C-80 capable of producing 40-80 MeV proton beams with a current of up to 200 μA has been constructed and commissioned at PNPI (Petersburg Nuclear Physics Institute). One of the main goals of cyclotron C-80 is the production of a wide spectrum of medical radionuclides for diagnostics and therapy. To date, the project development of a radioisotope facility RIC-80 (radioisotopes at cyclotron C-80) has been completed. The feature of the project is the use of a mass-separator combined with the ion-target device for obtaining ion beams of radioisotopes with a high purity of separation that is especially important for medical applications. The first results of a new high-temperature method for extracting 82Sr and 67Cu radioisotopes from irradiated targets have been presented.

  16. Entre Ricœur e Derrida: O Perdão Difícil e o Perdão Im-Possível/Between Ricoeur and Derrida: The difficult forgiveness and the Impossible forgiveness

    OpenAIRE

    Soares, Victor Dias Maia; Universidade do Estado do Rio de Janeiro / Universidade de Coimbra

    2017-01-01

    Este trabalho tem como objetivo principal promover o diálogo entre Paul Ricœur e Jacques Derrida no que concerne às abordagens que estes dois autores fazem da noção de perdão. A partir disso, discute-se primeiramente a ideia do perdão difícil em Ricœur e, num segundo momento, aquela do perdão im-possível em Derrida. Ainda que falem a partir de posições de fala diferentes, segundo idiomas filosóficos distintos, sustenta-se que a confrontação de ambas as perspectivas nos dá a pensar o perdão de...

  17. The chemical work of Alexander and Jane Marcet.

    Science.gov (United States)

    Rosenfeld, L

    2001-04-01

    Alexander Marcet was an authority on urinary calculi and their analysis when few medical practitioners appreciated the usefulness of chemistry in the explanation and treatment of disease. In An Essay on The Chemical History and Medical Treatment of Calculous Disorders, he described the discovery of an xanthine stone. He drew line illustrations of simple chemical apparatus useful for bedside analysis. His microtechnique used drops of solution and pinhead pieces of calculi; reagents were acids and alkalies and the blowpipe in conjunction with a small alcohol lamp. He reported the earliest description of a disorder later named "alcaptonuria". Marcet's work and that of a few others, on the chemical composition of urine and calculi, laid the foundations of our present knowledge. Between 1807 and 1820, his lectures to the medical students at Guy's Hospital were illustrated by experiments. Jane Haldimand Marcet wrote the very popular CONVERSATIONS: on Chemistry (16 editions in Great Britain). Her book dominated elementary chemical instruction during the first half of the 19th century. She followed Lavoisier's scheme of classification and explained chemical reactions in terms of affinity, aggregation, gravitation, and repulsion. Her advocacy that experimentation accompany lecture was new. The availability of serious scientific education in the new women's academies set the stage for increasing women's involvement in science. She also published a series of CONVERSATIONS: The topics were Political Economy, Natural Philosophy, and Vegetable Physiology.

  18. A cognitive robotics system: the symbolic and sub-symbolic robotic intelligence control system (SS-RICS)

    Science.gov (United States)

    Kelley, Troy D.; Avery, Eric

    2010-04-01

    This paper will detail the progress on the development of the Symbolic and Subsymbolic Robotics Intelligence Control System (SS-RICS). The system is a goal oriented production system, based loosely on the cognitive architecture, the Adaptive Control of Thought-Rational (ACT-R) some additions and changes. We have found that in order to simulate complex cognition on a robot, many aspects of cognition (long term memory (LTM), perception) needed to be in place before any generalized intelligent behavior can be produced. In working with ACT-R, we found that it was a good instantiation of working memory, but that we needed to add other aspects of cognition including LTM and perception to have a complete cognitive system. Our progress to date will be noted and the challenges that remain will be addressed.

  19. DOE/Industrial Technologies Program DOE Award Number DE-FG36-05GO15099 Plant Wide Energy Efficiency Assessment Pilgrims Pride Corporation – Mt Pleasant Facility

    Energy Technology Data Exchange (ETDEWEB)

    Paper, Riyaz; Dooley, Bill; Turpish, William J; Symonds, Mark; Carswell, Needham

    2007-04-13

    The U. S. Department of Energy’s (DOE) Industrial Technologies Program (ITP), through Oak Ridge National Laboratory, is supporting plant wide energy efficiency assessments that will lead to substantial improvements in industrial efficiency, waste reduction, productivity, and global competitiveness in industries identified in ITP’s Industries of the Future. The stated goal of the assessments is to develop a comprehensive strategy at manufacturing locations that will significantly increase plant productivity, profitability, and energy efficiency, and reduce environmental emissions. ITP awarded a contract to Pilgrim’s Pride Corporation to conduct a plant wide energy efficiency assessment for their Mt Pleasant Facility in Mt Pleasant, Texas. Pilgrim’s Pride Corporation is the largest poultry company in the U.S. and Mexico producing nearly 9 billion pounds of poultry per year. Pilgrim's Pride products are sold to foodservice, retail and frozen entrée customers. Pilgrim's Pride owns and operates 37 chicken processing plants (34 in the U.S. and three in Mexico), 12 prepared foods plants and one turkey processing plant. Thirty-five feed mills and 49 hatcheries support these plants. Pilgrim's Pride is ranked number 382 on 2006's FORTUNE 500 list and net sales were $7.4 billion. In Mt. Pleasant, Texas, Pilgrim's Pride operates one of the largest prepared foods plants in the United States, with the capability of producing 2,000 different products and the capacity to turn out more than 7 million pounds of finished goods per week. The facility is divided into distinct departments: East Kill, West Kill, Prepared Foods, Protein Conversion, Wastewater Treatment, and Truck Shop. Facility processes include killing, eviscerating, refrigeration, baking, frying, and protein conversion. Pilgrim’s Pride formed a team to complete the plant wide energy efficiency assessment. The scope of work for this project was to: provide the analysis of departmental

  20. The paths of salvation and eternal condemnation: The presence of the allegory in the History of the Elected Pilgrim and his Brother Precito (1682, de Alexandre de Gusmão

    Directory of Open Access Journals (Sweden)

    José Adriano Filho

    2015-04-01

    Full Text Available The repercussions of the echoes of the Council of Trent (1546-1563, the Counter Reform movement, and the repercussions they had on the artistic production in the Catholic world. The pedagogical-didactic intents behind its composition are grounded on the belief that art could be an effective tool for reconverting of the faithful and for indoctrination in the values of the Catholic faith. Considering that, this paper aims at presenting the way allegory became an important tool for the interpretation and construction of religious discourse, as we can see in the History of the Elected Pilgrim and his Brother Precito. The book is an allegorical narrative that presents the history of two pilgrim brothers born in Egypt from where they set out with the intention of making a fortune (one brother goes to Jerusalem, and the  other one goes to Babylon. In this way, the book presents continuity with the medieval pattern that highlights the journey, especially the path for salvation. The readiness of allegory to transmit abstract concepts through concrete visualizations allied to a form of indirect expression made it a powerful, didactic, apologetic, and entertaining tool for that time.

  1. Jane Austen's lifelong health problems and final illness: New evidence points to a fatal Hodgkin's disease and excludes the widely accepted Addison's.

    Science.gov (United States)

    Upfal, A

    2005-06-01

    Jane Austen is typically described as having excellent health until the age of 40 and the onset of a mysterious and fatal illness, initially identified by Sir Zachary Cope in 1964 as Addison's disease. Her biographers, deceived both by Cassandra Austen's destruction of letters containing medical detail, and the cheerful high spirits of the existing letters, have seriously underestimated the extent to which illness affected Austen's life. A medical history reveals that she was particularly susceptible to infection, and suffered unusually severe infective illnesses, as well as a chronic conjunctivitis that impeded her ability to write. There is evidence that Austen was already suffering from an immune deficiency and fatal lymphoma in January 1813, when her second and most popular novel, Pride and Prejudice, was published. Four more novels would follow, written or revised in the shadow of her increasing illness and debility. Whilst it is impossible now to conclusively establish the cause of her death, the existing medical evidence tends to exclude Addison's disease, and suggests there is a high possibility that Jane Austen's fatal illness was Hodgkin's disease, a form of lymphoma.

  2. Sur la soumission au pouvoir. Convergences et differences entre le Discours de la servitude volontaire d’Etienne de La Boétie et la pensée politique de Paul Ricœur

    Directory of Open Access Journals (Sweden)

    Pierre-Olivier Monteil

    2017-07-01

    Full Text Available This study undertakes a reading of Etienne de La Boétie’s Discours de la servitude volontaire, endeavoring to bring to light the way it convergences with and diverges from the political thought of Paul Ricœur, around the central concept of the will. On the basis of the twin notions of “denaturation” and of “pathology,” a course unfolds which aims at helping establish the people, in comparison with the institution of the State, through a political process revitalised by friendship. But the two thinkers differ when it comes to the resources of the will. This is reflected in the notion of freedom, conceived as absolute in La Boetie, while Ricœur emphasizes its contingency, which leads him to thematize it in terms of capabilities.

  3. JANE JACOBS. “MUERTE Y VIDA DE LAS GRANDES CIUDADES”

    Directory of Open Access Journals (Sweden)

    José Altés Bustelo

    2011-05-01

    Full Text Available La primera edición de este libro apareció en 1961 en Nueva York. (Random House Inc. Edit.. Y la primera traducción en castellano, de Angel Abad, apareció en España sorprendentemente pronto, en enero de 1967, editada por Península. (Ediciones 62, Barcelona.El texto de Jane Jacobs se inicia con su ya famosa frase: "Este libro es un ataque contra las teorías más usuales sobre urbanización y reconstrucción de ciudades,..." advertencia insólita, aunque innecesaria si uno continua leyendo.Fruto de la experiencia directa, atenta, sensible, perspicaz, abierta a la observación y marcada por el amor y compromiso con su ciudad, Nueva York, y sus convecinos, y contrastada con minuciosos análisis en múltiples otras ciudades, J.J. nos desgrana una extensa cadena de reflexiones sobre la experiencia vivida de la realidad cotidiana en las distintas escalas de la ciudad: calle, barriada, distrito, sus límites y fronteras, parques y vacíos, comunicaciones, etc., y la constatación detallada del fracaso, siempre, en la acción de políticos, planificadores y arquitectos

  4. Une lecture de Eine Übertragung de Wolfgang Hilbig à la lumière de Paul Ricœur.

    Directory of Open Access Journals (Sweden)

    Bénédicte Terrisse

    2009-12-01

    Full Text Available L’objet de cette étude est de comprendre le roman de Wolfgang Hilbig (1941-2007 Eine Übertragung (1989 à partir de La Métaphore vive de Ricœur et de l’analyse des différents sens du titre du roman (métaphore, transfert, transposition. L’esthétique métaphorique, qui rappelle en de nombreux points l’esthétique mallarméenne, permet à l’auteur de réinterpréter et redécrire la réalité est-allemande en même temps que sa propre biographie. Par le recours au mythe et à l’intertextualité, ces dernières sont assimilées à la modernité esthétique, si bien que la RDA devient le territoire de la littérature moderne. Par la métaphore, Hilbig se réapproprie une réalité définie jusqu’alors par un pouvoir discrétionnaire.Ziel dieses Textes ist es, den Roman Eine Übertragung (1989 von Wolfgang Hilbig (1941-2007 mit Hilfe von Ricœurs La Métaphore vive sowie der Analyse der verschiedenen Titelbedeutungen (als Metapher, Übertragung oder Übersetzung zu verstehen. Diese Ästhetik der Metapher, die in mancher Hinsicht an die Mallarmésche erinnert, ermöglicht es dem Autor, zugleich die Realität der DDR und seine eigene Biographie neu zu interpretieren und zu beschreiben. Durch Rekurs auf Mythos und Intertextualität werden sie der ästhetischen Moderne gleichgesetzt, sodass die DDR zum Ort der Literatur der Moderne wird. Auf diese Weise gelingt es Hilbig, sich eine bis dahin von der politischen Macht dekretierte Wirklichkeit wieder anzueignen.

  5. 9/11, Hyperreality, and the Global Body Politic: Frédéric Beigbeder’s Windows on the World

    Directory of Open Access Journals (Sweden)

    Jenn Brandt

    2015-01-01

    Full Text Available This essay argues that the success of Frédéric Beigbeder's Windows on the World is due to Beigbeder's use of the seemingly contradictory genres of autofiction and hyperrealism in the depiction of the terrorist attacks of September 11, 2001. By positioning himself in the text alongside his fictionalized American counterpoint, Beigbeder configures 9/11 as a lived-body experience that models the ways in which the post-9/11 subject was formed within specific political, cultural, and national conditions. The effect of the novel’s hyperrealism is such that Beigbeder simultaneously posits and deconstructs the notion of national identity within the greater contexts of postmodernism and globalization.

  6. Jane Austen e a recodificação paródica do gótico em Northanger Abbey

    Directory of Open Access Journals (Sweden)

    Genilda Azeredo

    2012-11-01

    The purpose of this essay is to discuss the constructions and effects of the parodic dialogue Jane Austen’s novel Northanger Abbey (1818 establishes with a tradition of Gothic literature in the eighteenth-century English context. Because it is considered as an expressive form of intertextuality, parody (both in the sense of ‘parallel song’ and ‘counter-song’ actively and creatively recodifies the tradition it parodies. As a consequence, studying such an articulation means being aware of a comparative interplay among codes, textualities, readings and literary traditions, so as to recognize the effects of parody as also articulated with a larger context of metafiction.

  7. La economía de las relaciones de género en "Orgullo y prejuicio" de Jane Austen

    Directory of Open Access Journals (Sweden)

    Sonia Herrera Sánchez

    2013-01-01

    Full Text Available El presente artículo pretende ser una aproximación con gafas de género a los sistemas de transmisión o ruptura del patriarcado a través de una de las obras más conocidas de la literatura inglesa de principios del siglo XIX: Orgullo y prejuicio, de Jane Austen. Para ello, se desentrañará el funcionamiento de la economía de género en la mencionada novela, confrontándolo con los procesos educativos de la época y los primeros indicios de individualización femenina en la sociedad moderna.

  8. [Doctor Albéric Pont (1870-1960). Dental surgeon, doctor and creator of the center of maxillo-facial surgery of Lyon in 1914].

    Science.gov (United States)

    Riaud, Xavier

    2008-01-01

    As Stomatologist and Dental Surgeon Albéric Pont founded with six other Dental Surgeons the School of Dentistry in Lyons which he ran for a long time. When he enlisted in the French Army in 1914 he soon became aware of the extent of facial damage that occurred among the injured soldiers. His subsequent decision was to create and run a Centre for maxillofacial surgery in Lyons. He died in 1960 and left a significant scientific work as well as technical elements of surgery, dental index and devices which still bear his name.

  9. From private to public redux: the private lives of Jane Austen and Graham Greene as represented by the public worlds of film

    OpenAIRE

    Gregory, Valerie

    2007-01-01

    This project is an examination of the process by which the mediums of literature and film intersect within the context of novel-to-film adaptation, and in the depiction of the public and private spheres of the authors and directors. The novels of Jane Austen and Graham Greene and three contemporary film adaptations of their work are analyzed. The project considers how the authors’ private and public lives influence their fiction, how the film directors’ private spheres alter their perception ...

  10. Connecting the Plots: The Extension of Return and Korean Ethnic Nationalism in Jane Jeong Trenka’s 'Fugitive Visions'

    Directory of Open Access Journals (Sweden)

    Ethan Waddell

    2017-05-01

    Full Text Available Thousands of overseas Korean adoptees return to Korea temporarily each year in search of their true origin, but few choose to stay permanently. A prominent member of this small community is Jane Jeong Trenka, author of two memoirs: The Language of Blood (2003 and Fugitive Visions: An Adoptee’s Return to Korea (2009. This article analyses Trenka’s literary struggle for permanence in Fugitive Visions through theories on Korean ethnic national identity. Using Marshall McLuhan’s idea of media as the ‘extension of man’, it explores the symbiotic relationship between literary media and identity, connecting colonial-era writings on Korean ethnic nationalism to Trenka’s portrayal of transnational return.

  11. « Et ils ne vécurent pas heureux » : la fin de Jane Eyre réécrite dans Charlotte de D.M. Thomas “And they didn’t live happily ever after”: D.M. Thomas’s Rewriting of the Ending of Jane Eyre in Charlotte

    Directory of Open Access Journals (Sweden)

    Armelle Parey

    2009-10-01

    Full Text Available D.M. Thomas’s rewriting of Jane Eyre in Charlotte (2000 takes the shape of a transformation of the ending which enables the second Mrs Rochester’s story to be continued in the West Indies, thus also acknowledging Jean Rhys’s Wide Sargasso Sea as another intertext. In order to challenge the narrative and ideological hierarchy of the source text by rewriting its ending, the pastiche defamiliarises it while some chapters set in 1999 move the limits of rewriting and take the reader into a narrative spiral.

  12. Combining metric episodes with semantic event concepts within the Symbolic and Sub-Symbolic Robotics Intelligence Control System (SS-RICS)

    Science.gov (United States)

    Kelley, Troy D.; McGhee, S.

    2013-05-01

    This paper describes the ongoing development of a robotic control architecture that inspired by computational cognitive architectures from the discipline of cognitive psychology. The Symbolic and Sub-Symbolic Robotics Intelligence Control System (SS-RICS) combines symbolic and sub-symbolic representations of knowledge into a unified control architecture. The new architecture leverages previous work in cognitive architectures, specifically the development of the Adaptive Character of Thought-Rational (ACT-R) and Soar. This paper details current work on learning from episodes or events. The use of episodic memory as a learning mechanism has, until recently, been largely ignored by computational cognitive architectures. This paper details work on metric level episodic memory streams and methods for translating episodes into abstract schemas. The presentation will include research on learning through novelty and self generated feedback mechanisms for autonomous systems.

  13. Characteristics of the assistance to pilgrims in the National Sanctuary of Our Lady of Aparecida, São Paulo, Brazil, 2011-2014.

    Science.gov (United States)

    Carmo, Hercules de Oliveira; Valente, Tânia Cristina Oliveira

    2017-01-01

    to describe the characteristics of the health assistance for pilgrims visiting the National Sanctuary of Our Lady of Aparecida and to investigate health care strategies in periods of peak of religious tourism. a descriptive study using outpatient medical records from 2011 to 2014, for a detailed analysis for the month of October 2014 and the operational documents for health care in periods of mass events in the medical clinic of the Sanctuary. 95,011 people were assisted in the period, 2,266 in October 2014; the higher demand for assistance was from elderly individuals (33%), women (59%), and people from the Brazilian Southeast region (79%); there were no operational documents for specific actions for this period. the large number of visitors, associated with the frequency of mass events and the absence of an operating plan, may pose a serious public health scenario for that region.

  14. Janeites for a New Millennium: The Modernisation of Jane Austen on Film

    Directory of Open Access Journals (Sweden)

    Elzette Steenkamp

    2009-05-01

    Full Text Available The late twentieth century saw a surge in cinematic adaptations of Jane Austen’s novels, the films generating wide-spread interest and zeal from a new caste of modern-day Janeites, many of whom were previously unfamiliar with Austen’s work. While the notion of a Janeite culture based purely on motion picture renditions of the original novels is sure to displease literary purists, the purpose of this discussion is not to initiate a debate regarding our responsibility to remain faithful to Austen in her original form. Rather, this article identifies the type of cinematic alterations and emphases which render Austen films more appealing to a certain group of modern-day Janeites. It will be argued that modern-day audiences’ demand for recognisably modern protagonists necessitates the modernization of Austen on film. Thus, cinematic adaptations tend to emphasize Austen’s nascent feminism, re-imagining her heroines as more fiercely independent, lively and witty than their original incarnations. Through additional scenes, altered dialogue and substantial changes to the characters, film producers not only highlight the plight of women in the early nineteenth century, but also circumvent such restrictions by allowing their female protagonists the degree of independence demanded by modern-day audiences.

  15. Mary Jane Hogue (1883-1962): A pioneer in human brain tissue culture.

    Science.gov (United States)

    Zottoli, Steven J; Seyfarth, Ernst-August

    2018-05-16

    The ability to maintain human brain explants in tissue culture was a critical step in the use of these cells for the study of central nervous system disorders. Ross G. Harrison (1870-1959) was the first to successfully maintain frog medullary tissue in culture in 1907, but it took another 38 years before successful culture of human brain tissue was accomplished. One of the pioneers in this achievement was Mary Jane Hogue (1883-1962). Hogue was born into a Quaker family in 1883 in West Chester, Pennsylvania, and received her undergraduate degree from Goucher College in Baltimore, Maryland. Research with the developmental biologist Theodor Boveri (1862-1915) in Würzburg, Germany, resulted in her Ph.D. (1909). Hogue transitioned from studying protozoa to the culture of human brain tissue in the 1940s and 1950s, when she was one of the first to culture cells from human fetal, infant, and adult brain explants. We review Hogue's pioneering contributions to the study of human brain cells in culture, her putative identification of progenitor neuroblast and/or glioblast cells, and her use of the cultures to study the cytopathogenic effects of poliovirus. We also put Hogue's work in perspective by discussing how other women pioneers in tissue culture influenced Hogue and her research.

  16. Behavioural Susceptibility Theory: Professor Jane Wardle and the Role of Appetite in Genetic Risk of Obesity.

    Science.gov (United States)

    Llewellyn, Clare H; Fildes, Alison

    2017-03-01

    There is considerable variability in human body weight, despite the ubiquity of the 'obesogenic' environment. Human body weight has a strong genetic basis and it has been hypothesised that genetic susceptibility to the environment explains variation in human body weight, with differences in appetite being implicated as the mediating mechanism; so-called 'behavioural susceptibility theory' (BST), first described by Professor Jane Wardle. This review summarises the evidence for the role of appetite as a mediator of genetic risk of obesity. Variation in appetitive traits is observable from infancy, drives early weight gain and is highly heritable in infancy and childhood. Obesity-related common genetic variants identified through genome-wide association studies show associations with appetitive traits, and appetite mediates part of the observed association between genetic risk and adiposity. Obesity results from an interaction between genetic susceptibility to overeating and exposure to an 'obesogenic' food environment.

  17. PERBINCANGAN MENGENAI HUKUMAN MATI TERKAIT KASUS BALI NINE DAN MARY JANE DALAM SITUS JEJARING SOSIAL TWITTER

    Directory of Open Access Journals (Sweden)

    Jimi Narotama Mahameruaji

    2016-06-01

    Full Text Available Twitter telah menjadi alat atau media komunikasi yang sangat populer diantara para pengguna Internet. Melalui Twitter, penggunanya dapat berbagi cerita hidup mereka sehari-hari, melakukan perbincangan dengan pengguna lain dan juga mengekspresikan pendapat mereka. Twitter juga dapat dilihat sebagai sebuah wadah untuk melakukan perbincangan politik dan isu-isu publik. Oleh karena itu, peran Twitter terkait partisipasi publik, kampanye, dan pembentukan opini publik kini semakin diperhitungkan (Jungherr, 2015. Fokus penelitian ini tentang perbincangan para pengguna Twitter di Indonesia mengenai peristiwa hukuman mati kasus narkoba Bali Nine dan Mary Jane. Penelitian ini bertujuan untuk mengetahui apa ragam perbincangan yang terjadi di antara para pengguna Twitter Indonesia terkait kasus hukuman mati tersebut, apa argumen yang muncul terkait penolakan maupun dukungan terhadap isu hukuman mati, dan juga siapa saja Twitter Influencer yang berperan dalam isu ini.   DOI: 10.24198/jkk.vol4n1.5

  18. Histoire et vérité chez Paul Ricœur et Thucydide: mimesis et enargeia

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    Martinho Tomé Soares

    2017-07-01

    Full Text Available Cet article essaye d’analyser l’Histoire de la Guerre du Péloponnèse de Thucydide à la lumière des thèses ricœuriennes sur l’épistémologie de la connaissance historique, notamment les trois moments essentiels de l’opération historiographique : la preuve documentaire, l’explication/compréhension et l’écriture/représentation. Ce qui nous amène à insérer le texte de Thucydide dans la séquence des trois phases de la mimésis impliquée dans toute mise en discours : préfiguration, configuration, refiguration. Le dialogue que nous établissons entre le philosophe français et l’historien grec nous permet aussi de trouver plusieurs dissimilitudes et similitudes entre les deux, soit en réfléchissant sur la question de la vérité, soit en réfléchissant sur la dialectique entre lire et voir, sous le signe du concept rhétorique de l’enargeia.

  19. Entretiens Jacques Cordonier, Alain Jacquesson, Jean-Frédéric Jauslin, Hubert Villard

    CERN Document Server

    2016-01-01

    Beaucoup d’usages sont tellement ancrés dans nos vies que l’on ne s’interroge guère sur la manière dont ils sont advenus. Les réseaux informatiques, les échanges qu’ils génèrent, semblent aujourd’hui aussi « naturels » aux digital natives que la conversation à distance par téléphones fixes allait de soi il y a cinquante ans. Pour autant que l’on se pose la question, il est difficile d’imaginer qu’un domaine institutionnel, celui des bibliothèques en l’occurrence, ait joué un rôle important dans l’avènement et l’expansion de ces réseaux, au plan suisse voire international, et, par voie de conséquence, dans le développement et la normalisation des échanges intercantonaux. Cela est néanmoins une réalité. Ce livre d’entretiens fait apparaître en quoi Jacques Cordonier, Alain Jacquesson, Jean-Frédéric Jauslin et Hubert Villard, directeurs romands parmi les plus marquants de la fin du 20 e siècle, chacun avec son regard et sa tessiture, dans son canton ou à ...

  20. Active screening and surveillance in the United Kingdom for Middle East respiratory syndrome coronavirus in returning travellers and pilgrims from the Middle East: a prospective descriptive study for the period 2013–2015

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    Sowsan F. Atabani

    2016-06-01

    Conclusions: Respiratory tract infections in travellers/pilgrims returning to the UK from the Middle East are mainly due to rhinoviruses, influenza A, and influenza B. Whilst MERS-CoV was not detected in the 202 patients studied, heightened awareness of the possibility of MERS-CoV and continuous proactive surveillance are essential to rapidly identify cases of MERS-CoV and other seasonal respiratory tract viruses such as avian influenza, in patients presenting to hospital. Early identification and isolation may prevent outbreaks in nosocomial settings.

  1. The Stories We Hear, the Stories We Tell What Can the Life of Jane Barker (1652-1732) Tell Us about Women's Leadership in Higher Education in the Twenty-First Century?

    Science.gov (United States)

    Wilson, Carol Shiner

    2009-01-01

    Jane Barker--poet, novelist, farm manager, student and practitioner of medical arts--was not allowed to attend university because she was a woman. Yet she was Oxford-educated in the most modern of medical theories of her time. By the end of her life, unmarried by choice, Barker was writing for pay under her own name in an emerging genre--the…

  2. Play the game in the opening scene A multidisciplinary lens for understanding (videoludic movies, including Super Mario Bros., Resident Evil and Scott Pilgrim vs. the World

    Directory of Open Access Journals (Sweden)

    Enrico Gandolfi

    2015-09-01

    Full Text Available The aim of this article is to create a multidisciplinary tool concerning the passage from the medium of videogames to cinema. According to concepts taken from Media Studies, Cultural Studies, Semiotics and Game Studies, we will explore the multiple dimensions and the related connections that occur in the film linearization of digital interaction: production issues, narrative and aesthetic elements, heuristics and mechanics in-game and on the big screen, and so on. The framework will be tested through three paradigmatic case studies: Super Mario, Resident Evil, and Scott Pilgrim vs. the World. The overall intent is to give scholars, and also practitioners, a holistic perspective on this peculiar type of crossmedia process, pointing out virtuous productive strategies as ruinous ones.

  3. Adaptation-induced Tourism for Consumers of Literature on Screen: the Experience of Jane Austen Fans

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    Maddalena Pennacchia

    2015-03-01

    Full Text Available My aim in this article is that of starting to relate the expanding research field of adaptation studies to the subject area of film-induced tourism. Adaptations are a specific typology of films: that is, films whose story was not originally intended for the screen but, more often than not, for the written page, and has, therefore, been ‘translated’ into a new medium. The phenomenon of adaptation has been at the center of a heated debate for a few years now, but the specific link between adaptation and tourism has not yet been studied in its own right. In my article I question why and how adaptations of literary texts for the screen can induce a desire to visit film locations (actual geographical places in readers who are also inclined to enjoy the experience of “literature on screen”. In order to do this, I focus on the case study of adaptations from Jane Austen’s novels and on a specific kind of tourists, the so called ‘Janeites’, or Austen fans.

  4. Cultivating Compassion and Youth Action Around the Globe: A Preliminary Report on Jane Goodall’s Roots & Shoots Program

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    Laura R. Johnson

    2007-09-01

    Full Text Available This paper describes a unique service-learning based environmental and humanitarian program for youth, The Jane Goodall Institute’s Roots and Shoots program (R&S. R&S aims to foster learning, personal growth and civic engagement among youth members through service activities and environmental education. Despite its promise as a youth development program and its rapid expansion into 100 countries, little is known about R&S’s impact on youth development. In this study, we explore R&S programs in China and Tanzania, two countries that are maximally different from the U.S. in important cultural and contextual factors. Through qualitative and quantitative methods we describe the programs, their practices, and perceptions of their impact on youths’ personal and social development (cognitive and social competence, leadership, self-efficacy, citizenship and social responsibility. Additionally, we highlight the importance of sociocultural and ecological factors when developing and evaluating youth programs.

  5. Living with diversity in Jane-Finch

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    Donya Ahmadi

    2017-11-01

    seeks to add to our understanding of urban diversity, as perceived and experienced by those who inhabit, frequent and govern urban areas. It answers the following primary research question: How is diversity experienced at the neighbourhood level, as (a discourse, (b social reality, and (c practice? Diversity as discourse refers to the public narratives around diversity, while diversity as social reality concerns the descriptive characteristics that render an area diverse. Diversity as practice refers to policies, programs and local practices that aim towards managing diversity (see also Berg and Sigona, 2013. The research question is investigated in four interconnected chapters, which engage with the three formerly mentioned dimensions to various degrees. The study further makes use of a variety of qualitative and participatory techniques (i.e. qualitative interviews, roundtable talks, participant observations, and focus groups to gather rigorous empirical data on living with and managing diversity in an inner-suburban neighbourhood of Toronto, namely Jane-Finch.

  6. Maxwell Fry and Jane Drew Partners : The Contributions of British Architects to Built Environment in Colonial Nigeria, 1946-1959

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    Abiodun Akeem Oladiti

    2016-06-01

    Full Text Available This paper examines the contributions of two British architects, Maxwell Fry and Jane Drew in the development of built environment in Nigeria after World War II. It analyses the historical development of the built environment in Nigeria’s public space with respect to modernize infrastructures such as banks, schools, teachers training colleges and the university needed in support of the colonial administration in Nigeria. The agitation of the nationalists and postwar reconstruction facilitated and encouraged the British Empire to develop the edifice or structures that would be suitable for the environment. This, to a large extent, influenced the Nigerian architecture and built environment. Their design principles yielded functional institutional spaces and a hybrid aesthetics that signifies modernist construction and colonial influence. The paper concludes that the designs of both Fry and Drew represent a milestone and significant contribution to the development of built environment in colonial Nigeria.

  7. ABORTION AND VIOLENCE IN JANE MARTIN’S KEELY AND DU: PRO-CHOICE, PRO-LIFE, OR MERELY PROVOCATIVE?

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    Eta Farmacelia Nurulhady

    2017-04-01

    Full Text Available Abortion and violence are global issues, yet different culture might respond to the issues somewhat differently. This study aims to reveal the abortion and violence issues in Jane Martin’s Keely and Du in terms of pro-choice and pro life movements and see how Indonesian students reading the play respond to the issues. In the United States of America, the discussion of abortion issue can be grouped into two major categories: the pro-life and pro-choice. In Indonesia, the majority of people would be against abortion when it is not for medical reasons. The students reading Keely and Du find the play challenging their beliefs as religious people still keeping hold of eastern values. Having discussed the nature of pro-life and pro-choice movements, it is difficult for them to decide whether they are proponent of either one. Keely and Du is successfully provocative in offering insight on how abortion and violence issues cannot be judged in a black and white manner.

  8. The Need for an Alternative Narrative to the History of Ideas or To Pay a Debt to Women: A Feminist Approach to Ricœur's Thought

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    Fernanda Henriques

    2013-06-01

    Full Text Available This paper explores the thought of Paul Ricœur from a feminist point of view. My goal is to show that it is necessary to narrate differently the history of our culture – in particular, the history of philosophy – in order for wommen to attain a self-representation that is equal to that of men. I seek to show that Ricoeur’s philosophy – especially his approach to the topics of memory and history, on the one hand, and the human capacity for initiative, on the other hand– can support the idea that it is possible and legitimate to tell our history otherwise by envisioning a more accurate truth about ourselves. 

  9. The Wheal Jane wetlands model for bioremediation of acid mine drainage

    International Nuclear Information System (INIS)

    Whitehead, P.G.; Cosby, B.J.; Prior, H.

    2005-01-01

    Acid mine drainage (AMD) is a widespread environmental problem associated with both working and abandoned mining operations. As part of an overall strategy to determine a long-term treatment option for AMD, a pilot passive treatment plant was constructed in 1994 at Wheal Jane Mine in Cornwall, UK. The plant consists of three separate systems, each containing aerobic reed beds, anaerobic cell and rock filters, and represents the largest European experimental facility of its kind. The systems only differ by the type of pretreatment utilised to increase the pH of the influent minewater (pH <4): lime dosed (LD), anoxic limestone drain (ALD) and lime free (LF), which receives no form of pretreatment. Historical data (1994-1997) indicate median Fe reduction between 55% and 92%, sulphate removal in the range of 3-38% and removal of target metals (cadmium, copper and zinc) below detection limits, depending on pretreatment and flow rates through the system. A new model to simulate the processes and dynamics of the wetlands systems is described, as well as the application of the model to experimental data collected at the pilot plant. The model is process based, and utilises reaction kinetic approaches based on experimental microbial techniques rather than an equilibrium approach to metal precipitation. The model is dynamic and utilises numerical integration routines to solve a set of differential equations that describe the behaviour of 20 variables over the 17 pilot plant cells on a daily basis. The model outputs at each cell boundary are evaluated and compared with the measured data, and the model is demonstrated to provide a good representation of the complex behaviour of the wetland system for a wide range of variables

  10. Peire Bremon Ricas Novas, “Rics pres, ferms e sobeirans” (BdT 330.15a

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    Paolo Di Luca

    2008-03-01

    Full Text Available This article provides a new critical edition and a commentary of Peire Bremon Ricas Novas’s “Rics pres, ferms e sobeirans”, a courtly love song composed between 1228 and 1257 and dedicated to Audiart del Baux. Built as a eulogy of the lady, the song focuses on the central theme of the moral and material ‘ricor’ (richness of the latter. The complexity of the metrical form, which displays a systematic use of the technique of ‘rim derivatiu’, is paralleled by the semantic obscurity of a number of verses and hapaxes, all discussed in the commentary. Stanzas III and IV show echoes of Jaufre Rudel’s “amor de lonh”, since the lover-poet declares that the distance and the ethnical difference between himself and the lady are abolished by the strength of his feelings. The use of ethnonyms in stanza IV is closely examined: the lover-poet reveals that he loves a Castilian lady who looks like a ‘Serrana’ (the name of an Iberian population, admitting that he would like her even if she were Catalan or Syrian. These references to the lady’s ethnical origins are puzzling: they can be read as a calembour with burlesque overtones, as well as a climax aiming to define the real provenance of the lady or as a rhetorical device to underline that courtly love does not know any kind of boundary.

  11. Diverging Interpretations of Charlotte Brontë’s Jane Eyre (1847: Franco Zeffirelli’s and Robert Stevenson’s Screen Adaptations Divergences interprétatives autour de Jane Eyre (1847 de Charlotte Brontë : les adaptations cinématographiques de Franco Zeffirelli et Robert Stevenson

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    Delphine Letort

    2009-07-01

    Full Text Available Franco Zeffirelli et Robert Stevenson nous offrent deux interprétations de Jane Eyre à travers des adaptations qui retiennent des choix narratifs souvent parallèles mais dont les mises en scène diffèrent, creusant un écart manifeste au niveau de la caractérisation du personnage éponyme. Le premier dramatise le récit pour souligner l’obstination de l’enfant et retracer le développement de la jeune femme tandis que le second adopte une approche hollywoodienne classique, utilisant le noir et blanc pour évoquer la fragilité de l’enfant et de la femme dans une structure sociale répressive soumise à l’autorité masculine. Les portraits esquissés par les réalisateurs reflètent des choix d’interprétation guidés par une lecture personnelle et contemporaine du récit de Charlotte Brontë.

  12. Les illusions perdues. Süssmilch, l’Académie de Berlin et Frédéric II : échec d’une politique de population

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    Jean-Marc Rohrbasser

    2011-08-01

    Full Text Available Le pasteur Süssmilch, après avoir publié en 1741 la première version de son ouvrage majeur, L’ordre divin dans les changements de l’espèce humaine, est agrégé à l’Académie des sciences de Prusse. L’ouvrage expose une application particulière d’une doctrine alors très en vogue : la théologie physique. En effet, selon Süssmilch, les phénomènes démographiques tels que la natalité, la nuptialité et la mortalité sont régis par la volonté divine et sa providence. À l’Académie, Süssmilch lit de nombreuses communications portant sur l’histoire de la Prusse, l’origine des langues et sur son objet de prédilection : l’explication des phénomènes démographiques par une régularité statistique elle-même ouvrage de Dieu.L’objet de la présente communication est de tenter d’expliquer pourquoi Süssmilch, pasteur luthérien, ne devient pas le conseiller du prince qu’il pense pouvoir être et aspire à être. Le pasteur déclare ouvertement avoir des visées pratiques, voire politiques. Sa position sociale et ses recherches sur la population en font un membre possible du gouvernement de l’état frédéricien. Il demeure cependant un haut fonctionnaire de la hiérarchie ecclésiastique luthérienne. Comment cela s’explique-t-il ?Après avoir sommairement décrit l’activité savante de Süssmilch à l’Académie et comment est accueilli et se diffuse le savoir qu’il tente d’y introduire, je montrerai qu’une conjoncture favorable à ses desseins politiques paraissait présider à sa carrière. Süssmilch arrive en effet au bon moment : il n’a que cinq ans de plus que Frédéric II, et l’accession au trône de ce dernier coïncide avec le début de la carrière du pasteur. Les circonstances sont favorables, et Süssmilch, indiquant l’utilité de ses recherches, insiste sur leur portée politique.J’exposerai ensuite en quoi le roi et le pasteur tombent d’accord. Les vues de Süssmilch et

  13. Definició de dues tipologies de vestit a través del seu ús històric: la indumentària d'arrel tradicional i el vestit d'inspiració internacional

    OpenAIRE

    Casal-Valls, Laura

    2015-01-01

    Resum:En aquest article s’estudia el vestit a través del seu ús històric per tal de definir-ne dues tipologies. A través d’una reflexió sobre les diferències entre el vestit i la moda, es defineixen dos grans grups d’indumentària: la indumentària tradicional i el vestit d’inspiració internacional. Tot i que aquest treball se centra en les col·leccions catalanes, la perspectiva d’estudi proposada pot servir per observar peces de geografies diverses.Resumen:Definición de dos tipologías de vesti...

  14. Odd complaints and doubtful conditions: norms of hypochondria in Jane Austen and Catherine Belling.

    Science.gov (United States)

    Nelson, James Lindemann

    2014-06-01

    In her final fragmentary novel Sanditon, Jane Austen develops a theme that pervades her work from her juvenilia onward: illness, and in particular, illness imagined, invented, or self-inflicted. While the "invention of odd complaints" is characteristically a token of folly or weakness throughout her writing, in this last work imagined illness is also both a symbol and a cause of how selves and societies degenerate. In the shifting world of Sanditon, hypochondria is the lubricant for a society bent on turning health into a commodity. As a result, people's rationality and their moral character come under attack. Catherine Belling's recent subtle study, A Condition of Doubt: The Meanings of Hypochondria, unveils hypochondria's discursive and cultural character. Running sharply against the tenor of Austen's treatment, however, she argues in defense of the rationality of hypochondriacs; the notion that the condition may involve morally significant defects is not entertained; any connection to the commercialization of health care is muted. Here, I contrast Austen's morally and epistemically negative rendering of her hypochondriacal characters in Sanditon with Belling's efforts to create a sympathetic understanding of people with hypochondria. I will argue that, despite time gaps and genre differences, joint consideration of these texts can help bioethicists better appreciate how medicine can intensify, pathologize, and exploit anxieties about illness and death, thus adding to the challenges of living well in the face of mortality and morbidity.

  15. P. R. Moore-Dewey’s “Pregiudizio e Orgoglio”: An Italian Remake of Jane Austen’s “Pride and Prejudice”

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    Eleonora Capra

    2017-12-01

    Full Text Available Since its publication in 1814, Jane Austen’s most famous novel, Pride and Prejudice, has enjoyed great success and has been the object of countless re-workings, re-mediations and adaptations on global scale. This essay aims at discussing a special instance of this phenomenon: an Italian re-make entitled Pregiudizio e Orgoglio (2012 and written by Austen enthusiast and admirer, P. R. Moore-Dewey (pseudonym of Patrizia Murreddu. I intend to analyze the change of perspective adopted by the author, who decided to re-write Austen's tale through the point of view of Mr. Darcy and his sister Georgiana. Moreover, it is my intention to look at some of the many intertextual references present in Moore-Dewey’s work and consider the impact of such references and quotations on the reading experience. Finally, I will consider the extensive use of paratextual devices, which contribute to define this work a particularly relevant literary manifestation.

  16. Reporting on What Jane Saw 2.0: Female Celebrity and Sensationalism in Boydell’s Shakespeare Gallery

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    Janine Barchas

    2015-03-01

    Full Text Available This essay reports on ongoing efforts to build an accurate digital model of John Boydell’s popular Shakespeare Gallery precisely as it looked in August 1796—when a 20-year-old Jane Austen visited London’s sites, staying within a ten-minute walk from the gallery. The essay argues for the substantial difference between studying Boydell’s pictures in a paper volume (whether as lists, illustrations in books, or engraved folio plates and viewing them as an exhibition of paintings on walls, albeit virtual ones. For example, the digital reconstruction illuminated commissions from several female participants in Boydell’s male-dominated gallery, especially Angelica Kauffman (1741-1807 and Anne Seymour Damer (1749-1828. In addition, the essay also recounts how the celebrity of model Emma Hart/Hamilton (1765-1815 safeguarded one Boydell painting from oblivion while The Shakespeare Gallery proved the site of a strange form of self-promotion practiced by actress Mary Wells (1762-1829. Our digital visualization of an historic exhibition in 1796 brought the controversial celebrity of a few women artists into focus. In sum, this essay shows DH methodology in action while sampling what might be gleaned when digital tools serve historical scholarship in the humanities.

  17. L’empathie comme outil herméneutique du soi: Note sur Paul Ricœur et Heinz Kohut

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    Michel Dupuis

    2011-01-01

    Full Text Available Le bref texte que Paul Ricœur consacre en 1986 à la psychanalyse développée par Heinz Kohut révèle une réinterprétation phénoménologique à la fois du contenu et des fonctions de l'empathie, au total considérée comme un véritable outil à l'œuvre dans l'herméneutique du soi. La vision kohutienne de la constitution du soi et du processus thérapeutique analytique produit une espèce de “dé-sentimentalisation” de l'empathie, en soulignant le rôle crucial du transfert intersubjectif, fort à distance de la théorie (freudienne solipsiste de l'ego.The short text published in 1986 by Paul Ricoeur about Heinz Kohut's psychoanalysis of the self reveals a phenomenological reinterpretation of the content and the functions of empathy, finally considered as an effective tool of the hermeneutics of the self. Kohut's model of constitution of the self and of the therapeutic analytical process produces a kind of “de-sentimentalization” of empathy, pointing to the crucial role of intersubjective transfer, far from a (Freudian solipsistic theory of the ego.

  18. Going beyond "First Impressions": Jane Austen on the spotlightDOI:10.5007/2175-8026.2010n59p101

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    Carla Alexandra Ferreira

    2010-03-01

    Full Text Available The last decades has seen a proliferation of Jane Austen’s novels for television and cinema. Despite being an important movement for the popularity of her literary work that has also brought some problems for a serious understanding of Austen’s literary project. The purpose of this essay is to point out the need of considering the changes, preferences and omissions, apparently not very important or carried out because of some demands of the translation from a novel to the cinema, that occur when her work is revisited. We will try to show some choices made in the transference from her novels to film may erase part of the writer’s fictional project which is among other things to portray women’s role in the nineteenth century patriarchal English society and try to change women’s condition of invisibility that had been created and spread since Enlightenment. In order to illustrate our point the 2005 version of Pride and Prejudice for the cinema will be used.

  19. The importance of biological oxidation of iron in the aerobic cells of the Wheal Jane pilot passive treatment system.

    Science.gov (United States)

    Hall, G; Swash, P; Kotilainen, S

    2005-02-01

    The passive treatment system designed to treat the mine water discharge of the abandoned Wheal Jane tin mine in Cornwall consisted of a sequence of artificial wetland cells, an anaerobic cell and a final series of rock filters. Three systems were operated which differed only in the pre-treatment of the mine water before discharge to the aerobic wetland cells. The aerobic cells were designed to promote aerobic oxidation and precipitation of iron which could exceed a concentration of 100 mg/l in the raw mine water discharge. The largest investment of land area was to the artificial wetland cells and it was important to understand the processes of oxidation and precipitation of iron so that the performance of this aspect the pilot passive treatment plant (PPTP) could be managed as efficiently as possible. The generally low pH of the influent mine water and inevitable trend of decreasing pH due to hydrolysis of Fe(III) meant that distinguishing between biotic and abiotic mechanisms was fundamental for further design planning of passive treatment systems. This paper describes these observations.

  20. New Trends of Pilgrimage: Religion and Tourism, Authenticity and Innovation, Development and Intercultural Dialogue: Notes from the Diary of a Pilgrim of Santiago

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    Corinto Gian

    2016-06-01

    Full Text Available The characteristics of our society are often contradictory. Despite the "liquidity" theorized by Bauman, aspects and practices deeply related (in appearance and/or in substance with spirituality hold great importance in our days. Among these practices, we found the pilgrimages. In this article we analyse this phenomenon in one of its best-known forms, the religious pilgrimage, in particular that of the Camino de Santiago. Today this forms of “travelling”, the pilgrimage, is studied as a tourism product and a vehicle of local development, and many studies already analysed the profiles and the motivations of the “new pilgrims”, as well as their economic impacts. Nevertheless, we felt the necessity to meet directly the pilgrims and share this experience with them without any filter. We became part of them, by addressing their perception toward their overall experience, using a qualitative approach based on direct observation and unstructured interviews. We collected data during a 400 kilometres walk towards Santiago de Compostela, which enabled us to create a clear overview on this specific, increasing phenomenon: a pilgrimage between religion and tourism, authenticity and innovation, local development and intercultural dialogue.

  1. Paul Ricœurs Suche nach einer Neubegründung der Menschenrechte und der Würde durch die Fähigkeiten und die Anwendung der phronèsis

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    Yvanka B. Raynova

    2016-12-01

    The aim of the following article is to reconstruct Paul Ricoeur's concepts of human rights and human dignity by exploring some little-known texts, and to exemplify how these concepts are connected to a specific philosophical conception of human being, which is grounded in a Dialectics between transcendence and incarnation, freedom and dependence, identity and difference, capability and fallibility (fragility. In doing so, I will argue that Ricœur interprets human dignity, which he has never explicitly defined, through the prism of human capabilities, especially of the capability of being responsible. This interpretation allows him to take a differentiated position in the current bioethical debates on the rights of "potential persons" (Embrio and to illustrate how the Aristotelian phronèsis can be used in (bioethical cases where decisions are difficult to take.

  2. Umbilical cord blood as an alternative source of reduced-intensity hematopoietic stem cell transplantation for chronic Epstein-Barr virus-associated T or natural killer cell lymphoproliferative diseases.

    Science.gov (United States)

    Sawada, Akihisa; Inoue, Masami; Koyama-Sato, Maho; Kondo, Osamu; Yamada, Kayo; Shimizu, Mariko; Isaka, Kanako; Kimoto, Tomiko; Kikuchi, Hiroaki; Tokimasa, Sadao; Yasui, Masahiro; Kawa, Keisei

    2014-02-01

    Chronic Epstein-Barr virus-associated T/natural killer cell lymphoproliferative diseases represented by chronic active Epstein-Barr virus infection are lethal but are curable with several courses of chemotherapy and allogeneic hematopoietic stem cell transplantation (HSCT). Recently, we reported that reduced-intensity conditioning (RIC) provided better outcomes than myeloablative conditioning because RIC was less toxic. However, it was unclear whether cord blood transplantation (CBT) works in the context of RIC. We retrospectively analyzed 17 patients who underwent RIC followed by bone marrow transplantation (RIC-BMT) and 15 patients who underwent RIC followed by CBT (RIC-CBT). The representative regimen was fludarabine and melphalan based. The overall survival rates with RIC-BMT and RIC-CBT were 92.9% ± 6.9% and 93.3% ± 6.4%, respectively (P = .87). One patient died of lung graft-versus-host disease after RIC-BMT, and 1 patient died of multiple viral infections after RIC-CBT. Although cytotoxic chemotherapy was also immunosuppressive and might contribute to better donor cell engraftment after RIC-HSCT, the rate of engraftment failure after RIC-CBT was still higher than that after RIC-BMT (not significant); however, patients who had experienced graft failure were successfully rescued with a second HSCT. Unrelated cord blood can be an alternative source for RIC-HSCT if a patient has no family donor. Copyright © 2014 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.

  3. Trichomonas vaginalis Repair of Iron Centres Proteins: The Different Role of Two Paralogs.

    Science.gov (United States)

    Nobre, Lígia S; Meloni, Dionigia; Teixeira, Miguel; Viscogliosi, Eric; Saraiva, Lígia M

    2016-06-01

    Trichomonas vaginalis, the causative parasite of one of the most prevalent sexually transmitted diseases is, so far, the only protozoan encoding two putative Repair of Iron Centres (RIC) proteins. Homologs of these proteins have been shown to protect bacteria from the chemical stress imposed by mammalian immunity. In this work, the biochemical and functional characterisation of the T. vaginalis RICs revealed that the two proteins have different properties. Expression of ric1 is induced by nitrosative stress but not by hydrogen peroxide, while ric2 transcription remained unaltered under similar conditions. T. vaginalis RIC1 contains a di-iron centre, but RIC2 apparently does not. Only RIC1 resembles bacterial RICs on spectroscopic profiling and repairing ability of oxidatively-damaged iron-sulfur clusters. Unexpectedly, RIC2 was found to bind DNA plasmid and T. vaginalis genomic DNA, a function proposed to be related with its leucine zipper domain. The two proteins also differ in their cellular localization: RIC1 is expressed in the cytoplasm only, and RIC2 occurs both in the nucleus and cytoplasm. Therefore, we concluded that the two RIC paralogs have different roles in T. vaginalis, with RIC2 showing an unprecedented DNA binding ability when compared with all other until now studied RICs. Copyright © 2016 Elsevier GmbH. All rights reserved.

  4. Biochemical signaling by remote ischemic conditioning of the arm versus thigh: Is one raise of the cuff enough?

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    Cameron Dezfulian

    2017-08-01

    Full Text Available Remote Ischemic Conditioning (RIC, induced by brief cycles of ischemia and reperfusion, protects vital organs from a prolonged ischemic insult. While several biochemical mediators have been implicated in RIC's mechanism of action, it remains unclear whether the localization or “dose” of RIC affects the extent of protective signaling. In this randomized crossover study of healthy individuals, we tested whether the number of cycles of RIC and its localization (arm versus thigh determines biochemical signaling and cytoprotection. Subjects received either arm or thigh RIC and then were crossed over to receive RIC in the other extremity. Blood flow, tissue perfusion, concentrations of the circulating protective mediator nitrite, and platelet mitochondrial function were measured after each RIC cycle. We found that plasma nitrite concentration peaked after the first RIC cycle and remained elevated throughout RIC. This plasma nitrite conferred cytoprotection in an in vitro myocyte model of hypoxia/reoxygenation. Notably, though plasma nitrite returned to baseline at 24 h, RIC conditioned plasma still mediated protection. Additionally, no difference in endpoints between RIC in thigh versus arm was found. These data demonstrate that localization and “dose” of RIC does not affect cytoprotection and further elucidate the mechanisms by which nitrite contributes to RIC-dependent protection.

  5. Influenza not MERS CoV among returning Hajj and Umrah pilgrims with respiratory illness, Kashmir, north India, 2014-15.

    Science.gov (United States)

    Koul, Parvaiz A; Mir, Hyder; Saha, Siddhartha; Chadha, Mandeep S; Potdar, Varsha; Widdowson, Marc-Alain; Lal, Renu B; Krishnan, Anand

    The increasing reports of Middle East Respiratory Syndrome (MERS) caused by MERS coronavirus (MERS-CoV) from many countries emphasize its importance for international travel. Muslim pilgrimages of Hajj and Umrah involve mass gatherings of international travellers. We set out to assess the presence of influenza and MERS-CoV in Hajj/Umrah returnees with acute respiratory infection. . Disembarking passengers (n = 8753) from Saudi Arabia (October 2014 to April 2015) were interviewed for the presence of respiratory symptoms; 977 (11%) reported symptoms and 300 (age 26-90, median 60 years; 140 male) consented to participate in the study. After recording clinical and demographic data, twin swabs (nasopharyngeal and throat) were collected from each participant, pooled in viral transport media and tested by real-time RT PCR for MERS-CoV and influenza A and B viruses and their subtypes. The participants had symptoms of 1-15 days (median 5d); cough (90%) and nasal discharge (86%) being the commonest. None of the 300 participants tested positive for MERS-CoV; however, 33 (11%) tested positive for influenza viruses (A/H3N2 = 13, A/H1N1pdm09 = 9 and B/Yamagata = 11). Eighteen patients received oseltamivir. No hospitalizations were needed and all had uneventful recovery. Despite a high prevalence of acute respiratory symptoms, MERS coV was not seen in returning pilgrims from Hajj and Umrah. However detection of flu emphasises preventive strategies like vaccination. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Cell lines derived from a Medaka radiation-sensitive mutant have defects in DNA double-strand break responses

    International Nuclear Information System (INIS)

    Hidaka, Masayuki; Oda, Shoji; Mitani, Hiroshi; Kuwahara, Yoshikazu; Fukumoto, Manabu

    2010-01-01

    It was reported that the radiation-sensitive Medaka mutant 'ric1' has a defect in the repair of DNA double-strand breaks (DSBs) induced by γ-rays during early embryogenesis. To study the cellular response of a ric1 mutant to ionizing radiation (IR), we established the mutant embryonic cell lines RIC1-e9, RIC1-e42, RIC1-e43. Following exposure to γ-irradiation, the DSBs in wild-type cells were repaired within 1 h, while those in RIC1 cells were not rejoined even after 2 h. Cell death was induced in the wild-type cells with cell fragmentation, but only a small proportion of the RIC1 cells underwent cell death, and without cell fragmentation. Although both wild-type and RIC1 cells showed mitotic inhibition immediately after γ-irradiation, cell division was much slower to resume in the wild-type cells (20 h versus 12 h). In both wild-type and RIC1 cells, Ser139 phosphorylated H2AX (γH2AX) foci were formed after γ-irradiation, however, the γH2AX foci disappeared more quickly in the RIC1 cell lines. These results suggest that the instability of γH2AX foci in RIC1 cells cause an aberration of the DNA damage response. As RIC1 cultured cells showed similar defective DNA repair as ric1 embryos and RIC1 cells revealed defective cell death and cell cycle checkpoint, they are useful for investigating DNA damage responses in vitro. (author)

  7. Jane Austen y C. S. Lewis: de la literatura al cine. Análisis de transposición

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    Mercedes Sarapura Sarapura

    2016-11-01

    Full Text Available Esta es una propuesta de análisis de transposición de la literatura al cine de la novela Orgullo y Prejuicio, de Jane Austen, y del ensayo Una pena observada, de C. S. Lewis. El primer propósito en ambos casos es ahondar en los nuevos aportes de la última versión cinematográfica de la novela de Austen, así como en las características y cualidades de la versión fílmica del cuaderno de anotaciones de C. S. Lewis, a partir de las contribuciones teóricas de autores como Gerard Genette, Georffrey Wagner, Brian Mcfarlane, entre otros. El segundo objetivo se orienta al reconocimiento del intercambio entre el lenguaje cinematográfico y literario como un proceso representativo de la sociedad actual. El hecho de que las adaptaciones (históricamente vistas con gran escepticismo sean ahora continuamente realizadas y acogidas por el público, insta a una revisión y profundización de los estudios que se han hecho al respecto con el fin de conocer la situación actual de la relación existente entre cine y literatura, sus posibilidades creativas, las expectativas de las audiencias, los prejuicios y recelos de los expertos, etc.

  8. Characterization of Radiation Induced Current in RF coils of Linac-MR Systems

    Science.gov (United States)

    Burke, Benjamin Lester

    Real-time MR imaging of the cancer patients undergoing external beam radiation treatment represents the next generation in image guided radiotherapy. However, the radio frequency (RF) coil of the MRI is exposed to the pulsed radiation of the linear accelerator in the systems where a medical linear accelerator is integrated with the MRI. This thesis is primarily concerned with the instantaneous effect of pulsed radiation on the RF coils, in particular the Radiation Induced Current (RIC). The RIC results from the charge imbalance created by the ejection of Compton electrons from the thin conductors of the RF coils during the pulsed irradiation. This work spans the initial observations of the RIC in real coils, a detailed characterization of the RIC and finally its impact on the MR image. The first part presented the measurements of the instantaneous RIC in two different MRI RF coils. Some basic characterization of the RIC included the isolation of the RF coil component responsible for RIC, the dependence of RIC on linear accelerator dose rate, and the effect of placing wax buildup on the coil to reduce RIC. The copper windings of the RF coils were isolated as the main source of RIC. A linear dependence of the RIC amplitude on dose rate was observed. The RIC was decreased with wax buildup, suggesting an electronic disequilibrium as the cause of RIC. In the second part, a buildup method of RIC removal in planar conductors is tested, a Monte Carlo method of RIC calculation in metal conductors is presented and validated, and the Monte Carlo method is used to examine the effects of magnetic fields on both planar conductor and practical cylindrical coil geometries. The buildup method of RIC removal is effective in planar geometries and in cylindrical coil geometries when the coil conductor is in direct contact with the patient. The presence of air gap between the coil and patient makes this method of RIC removal less effective although placing buildup still reduces the RIC

  9. 从穆勒的功利主义看简·爱在婚姻与宗教上的伦理观%From John Mill's Utilitarianism to Observe Jane Eyre's Marital and Religious Ethics

    Institute of Scientific and Technical Information of China (English)

    李俊宇

    2013-01-01

    In 19th century in Britain, there are many colliding mutually social ideas, one of which is Mill's utilitarianism. Mill holds the view that happiness is the only worth preserving aim. Jane Eyre's marital and religious ethics are consistent with Mill's utilitarianism. She protests against regarding ben-efit as only aim, sacrificing dignity and freedom to get happiness, and utilizing others and being utilized by others. Jane Eyre's ethics are due to British society's attaching importance to reason and utility, and Charlotte's laying emphasis on virtue cultivation. Jane Eyre utilitarianism not only changes the female's dependence on the male, humans' humble position to God, but also exposes the male's humanity. It seems that Charlotte points out a way of pursuing existence, development and gaining happiness for the women from low and middle class.%十九世纪的英国,各种思潮涌动,穆勒的功利主义主张幸福是唯一值得欲求的目的。简·爱在婚姻和宗教上的伦理观契合了穆勒的功利主义,并反对以利益为唯一追求目标的“功利观”,反对牺牲尊严、自由、人格完整来获取幸福,也反对利用他人和被他人利用。简·爱式的功利主义婚姻观和宗教观既是十九世纪英国社会重理性、重“实用”的产物,也是夏洛特重视伦理道德修养的产物。这种功利主义伦理观不仅调整了女性对应于男性的依附关系,而且改变了人对应于神的屈从地位,彰显了女性的主体人格。夏洛特通过叙述简的成长道路,似乎给当时代的中下层女性指明了一条求生存、求发展、实现真正幸福的道路。

  10. Mesures d’eficàcia publicitària i models teòrics de processament de la publicitat en formats off i online

    Directory of Open Access Journals (Sweden)

    Miriam Molina Garcia

    2013-06-01

    Full Text Available L’eficàcia publicitària ha estat i continua sent estudiada per diferents autors utilitzant varies mesures i establint diferents models. S’ha recollit estudis i investigacions dels sector i s’ha observat quines són algunes de les mesures més utilitzades per a l’estudi de l’eficàcia publicitària de formats off i online en els últims anys i en l’actualitat, els resultats són els següents; l’actitud cap a l’anunci (AA, l’actitud cap a la marca (AM, l’actitud cap al producte (AP i la intencionalitat de compra (IC. Amb el temps s’han creat diferents models teòrics per a l’estudi del processament de persuasió publicitària com el Elaboration Likelihood Model (ELM o el Advertising Response Modeling (ARM entre altres. En el present recull d’estudis s’observa com la gran majoria de models de persuasió publicitària no són vigents i funcionals per a l’estudi de l’eficàcia de la publicitat de formats interactius com poden ser els; banners, SMS’s, advergames o branded apps, amb l’excepció d’un model teòric clau que ha marcat un abans i un després en l’àrea d’estudi comentada, el ELM. Validity of theoretical models and advertising effectivness mesures with interactive advertising forms  Abstract The effectiveness of advertising has been and continues to be studied by different authors using various measures and establishing different models. Studies and  research has been collected and it has been observed which measures are most used for the study of advertising effectiveness in recent years and at present, the results are as follows; attitude toward the ad (AA, attitude toward the brand (AM, attitude toward the product (AP and purchase intention (IC. Over time, different theoretical models have been created to study the processing of persuasive advertising as the Elaboration Likelihood Model (ELM and the Advertising Response Modeling (ARM among others. This collection of studies shows how the

  11. Religiously Motivated Travel and Rural Tourism in Vhembe District of South Africa

    Directory of Open Access Journals (Sweden)

    Gyekye Agyapong

    2014-01-01

    Full Text Available The study investigated the socio-economic impact of religious tourism (UAAC gathering on the local tourism industry and on surrounding rural communities in Vhembe District Municipality (VDM of South Africa. Questionnaires were used to collect data on pilgrims (visitors, businesses, and residents during, and immediately after the event. Statistical techniques were used to analyse the data to gain insight into the data as basis for answering the research questions posed in this study. The results revealed that majority of the pilgrims to the UAAC gathering were from the host province of Limpopo. Also, most pilgrims travel to the pilgrimage site solely for religious reasons. Another significant finding is that the average spending per pilgrim by pilgrims from the rest of South Africa is larger than their Limpopo and foreign pilgrim counterparts. Furthermore, the results showed that while businesses were positive about the pilgrimage’s contribution to increased sales from their businesses, they at the same time opined that the event does not generate any additional employment. This could be because out of every R100 of pilgrims spending only R2.16 remains in the local economy through leakages. Finally an important finding of the study is overall consensus among residents that the annual pilgrimage gathering promotes morality, improved socialization as well as a sense of feeling good and proud of their community.

  12. SENSITIVITAS KUMAN NEISSERIA MENINGITIDIS YANG DIISOLASI DARI JAMAAH HAJI INDONESIA TERHADAP BEBERAPA ANTIBIOTIK

    Directory of Open Access Journals (Sweden)

    Muljati Prijanto

    2012-09-01

    Full Text Available The meningitis meningococcal disease caused by Neisseriae meningitidis is an infection of meninges and cerebrospinal fluid (CSF of the brain and the spinal cord. N. meningitidis is classified into 13 serogroups based on the immunologic reactivity of the capsular polysaccharide. Since 1993 the number of cases and carriers of haj pilgrims from Indonesia have increased. In 1996 the carrier rate was 9,4%, and case fatality rate of Indonesian haj pilgrims in Saudi Arabia was 71,4%. The dominant serogroup was serogroup B. The meningitis vaccine of serogroup B is not available yet. Until now there is not enough information of the laboratory results from the hospital in Saudi Arabia, regarding the strain that caused the infection of haj pilgrims from Indonesia. To prevent transmission of the disease among Haj pilgrims, since 1997, chemoprophylaxis with ciprofloxacine has been given to close contact persons of haj pilgrim patient. The objectives of this study are: First, to know the effectiveness of ciprofloxacin in decreasing the carrier rate of meningitis meningococcus in haj pilgrims. Second, to identify the serogroup of N. meningitidis isolated from carrier or patient and thirdly to know the sensitivity of bacteria to several antibiotics recommended by WHO. Nasofaringeal swabs were taken from 914 haj pilgrims from group of contact person of cases or suspected cases and 311 haj pilgrims from control group at embarkation in Jakarta. Ciprofloxacin was given to the study group in Saudi Arabia. Isolation and serogrouping were carried out for serogroup A, B, C. The result shows that the effectiveness of ciprofloxacin to N. meningitidis in the treated group were 98.58% and control were 85.54%, respectively. The serogroup of N. meningitidis is isolated from 13 carriers of treated group 69,23% could not be classified as serogroup A, B, or C. In the control group, 45 isolated strains from carriers consist of serogroup B 40%, serogroup C 28,9%, serogroup A 20

  13. “WEALTH OR LOVE, WHAT DOES A WOMAN WANT?” AN IRONIC LOOK AT THE MIDDLE CLASS NORMS IN CHARLOTTE BRONTE’S JANE EYRE

    Directory of Open Access Journals (Sweden)

    Afina Murtiningrum

    2017-02-01

    Full Text Available Jane Eyre is a novel written in the early nineteenth century (1847. It depicts the English society of the upper, middle and lower class and their habits and attitudes towards life. The opening of the novel points to social class, wealth and marriage as its major theme. Throughout the novel, the relationship between social awareness of class and marriage, especially dealing with money or property are highlighted, the reason why society tends to consider about social class, money and property in finding a suitable partner to marry. This paper relies on the examples from the novel to show how nineteenth-century women imagined their marriage. In terms of women’s social rights and roles, Charlotte Bronte tries to open readers' eyes to the idea that women's abilities should not be limited only to the sphere of the family. Bronte’s novel does not only attack Victorian class structure but also the issue of gender.   Keywords : marriage, wealth, property, women’s roles, gender

  14. Expected immunizations and health protection for Hajj and Umrah 2018 -An overview.

    Science.gov (United States)

    Al-Tawfiq, Jaffar A; Gautret, Philippe; Memish, Ziad A

    2017-09-01

    The annual Hajj and Umrah are one of the largest recurring religious mass gatherings across the globe drawing pilgrims from more than 185 countries. The living circumstances and activities of the pilgrims may create an environment for the occurrence and spread of communicable diseases. Each year, the Health authority of the Kingdom of Saudi Arabia, in coordination with international health authorities, updates health requirements for pilgrims. The Hajj for 2017 took place from August 24 to September 5, 2017. Here, we review the expected obligations for immunizations for the 2018 Hajj and Umrah. The Hajj and Umrah vaccine requirements include mandatory vaccinations against yellow fever, quadrivalent meningococcal polysaccharide (every 3 years) or conjugated (every 5 years) vaccines and poliomyelitis vaccine. Influenza vaccine utilizing the 2016 (Southern Hemisphere vaccine to all pilgrims) was recommended but was not obligatory for pilgrims. Ciprofloxacin is required for individuals >12 years excluding pregnant women as chemoprophylaxis to be given at the port of entry for Pilgrims coming from the meningitis belt. With the ongoing outbreaks of measles in Europe, it is recommended that all pilgrims have an updated immunization against vaccine-preventable diseases (diphtheria, tetanus, pertussis, polio, measles and mumps). The mandatory vaccines remain the same with continued vigilance for the development of any new or emerging infectious diseases. Continuing surveillance for Zika virus, cholera and MERS-CoV are ongoing. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Reference: 198 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available etion of either RIC4 or RIC3 causes tip growth defects that are rescued by overproduction or depletion...C4. RIC4 promotes F-actin assembly, whereas RIC3 activates Ca(2+) signaling that leads to F-actin disassembly. Overproduction or depl

  16. Rituximab-containing reduced-intensity conditioning improves progression-free survival following allogeneic transplantation in B cell non-Hodgkin lymphoma

    Directory of Open Access Journals (Sweden)

    Narendranath Epperla

    2017-06-01

    Full Text Available Abstract Background In B cell non-Hodgkin lymphoma (B-NHL, rituximab-containing reduced-intensity conditioning regimens (R-RIC have been shown to provide favorable outcomes in single-arm studies; however, large multicenter studies comparing R-RIC and non-rituximab-containing reduced-intensity conditioning regimens (nonR-RIC have not been performed. Using the CIBMTR database, we report the outcomes of R-RIC versus nonR-RIC regimens in B-NHL. Methods We evaluated 1401 adult B-NHL patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT who received nonR-RIC (n = 1022 or R-RIC (n = 379 regimens. Graft-versus-host disease (GVHD prophylaxis was limited to calcineurin inhibitor-based approaches. Results Median follow-up of survivors in the R-RIC and nonR-RIC groups was 47 and 37 months, respectively. On multivariate analysis, no difference was seen between the R-RIC and nonR-RIC cohorts in terms of acute GVHD grade II–IV (RR = 1.14, 95%CI = 0.83–1.56, p = 0.43 or grade III–IV (RR = 1.16, 95%CI = 0.72–1.89, p = 0.54, chronic GVHD (RR = 1.15, 95%CI = 0.92–1.46, p = 0.22, non-relapse mortality (RR = 0.90; 95%CI = 0.67–1.22; p = 0.51, relapse/progression (RR = 0.79; 95%CI = 0.63–1.01; p = 0.055, and mortality (RR = 0.84, 95%CI = 0.69–1.02, p = 0.08 risk. However, R-RIC was associated with a significantly improved progression-free survival (RR = 0.76; 95%CI 0.62–0.92; p = 0.006. On subgroup analysis, mortality benefit was noted in the R-RIC group patients not receiving busulfan-based RIC (RR = 0.76; 95%CI = 0.60–0.96; p = 0.02 and with the use of a higher cumulative rituximab dose (RR = 0.43; 95%CI = 0.21–0.90; p = 0.02. Conclusion Our analysis shows that inclusion of rituximab in RIC regimens improves progression-free survival in patients with B cell NHL. These data supports the use of R-RIC in B

  17. Ilmusid Ollinovski ja Pessoa kogud

    Index Scriptorium Estoniae

    2009-01-01

    Ollinovski, Jim. Aeroplaan esimesest pilgust. Tallinn : Pilgrim, 2009 ; Pessoa, Fernando. Tubakapood : ́Alvaro de Campose viimased luuletused. Tallinn : Pilgrim Group, 2009. Esitlus 2. dets. Tallinnas Von Krahli teatris

  18. Radiation induced currents in MRI RF coils: application to linac/MRI integration

    Science.gov (United States)

    Burke, B.; Fallone, B. G.; Rathee, S.

    2010-02-01

    The integration of medical linear accelerators (linac) with magnetic resonance imaging (MRI) systems is advancing the current state of image-guided radiotherapy. The MRI in these integrated units will provide real-time, accurate tumor locations for radiotherapy treatment, thus decreasing geometric margins around tumors and reducing normal tissue damage. In the real-time operation of these integrated systems, the radiofrequency (RF) coils of MRI will be irradiated with radiation pulses from the linac. The effect of pulsed radiation on MRI radio frequency (RF) coils is not known and must be studied. The instantaneous radiation induced current (RIC) in two different MRI RF coils were measured and presented. The frequency spectra of the induced currents were calculated. Some basic characterization of the RIC was also done: isolation of the RF coil component responsible for RIC, dependence of RIC on dose rate, and effect of wax buildup placed on coil on RIC. Both the time and frequency characteristics of the RIC were seen to vary with the MRI RF coil used. The copper windings of the RF coils were isolated as the main source of RIC. A linear dependence on dose rate was seen. The RIC was decreased with wax buildup, suggesting an electronic disequilibrium as the cause of RIC. This study shows a measurable RIC present in MRI RF coils. This unwanted current could be possibly detrimental to the signal to noise ratio in MRI and produce image artifacts.

  19. Silêncio e “manhas”: formas de resistência do subalterno em Jane Eyre

    Directory of Open Access Journals (Sweden)

    Charles Albuquerque Ponte

    2015-06-01

    Full Text Available Este trabalho tem como objetivo analisar as estratégias de resistência dos subalternos em Jane Eyre (2008, romance de Charlotte Brontë publicado originalmente em 1847, a partir de uma interpretação pós-colonialista. As personagens enfatizadas serão as oriundas da Jamaica, Bertha Mason e seu irmão, Richard, utilizando os modelos de resistência que Ascroft, Griffiths e Tiffin (2010 definem como ab-rogação e apropriação e as que Bhabha (2010 menciona como sly civility (cortesia dissimulada e mímica. Bertha Mason, a principal representante da subalternidade, faz mais uso da sly civility e da ab-rogação, enquanto Richard Mason utiliza-se mais da mímica e da apropriação, isso porque a colonizada repudia a cultura do centro, ao negar a linguagem europeia, diferentemente do irmão, que procura a imitação, ao apropriar-se do discurso do europeu para garantir seu lugar social, e, desse modo, o hibridismo cultural. Considerada louca e não tendo voz no romance, Bertha Mason desperta a nossa curiosidade acerca da honestidade da narradora, por esta ser branca e seu discurso ser construído a partir de discursos de personagens também brancos, principalmente o de Rochester cujo casamento com a autóctone fora considerado uma empreitada colonial. Dessa forma, somos motivados a compreender a exclusão dos subalternos do mundo simbólico, em correlação com sua procedência racial, cultural e mental, extraindo disso a possibilidade de as cesuras discursivas simbolizarem a opressão e repressão coloniais de uma assujeitação violenta. No entanto, isso não atesta a anulação do sujeito subalterno, pois mesmo censurado, discursivamente, encontra alternativas para resistir às forças colonizadoras.

  20. Inference of personality projected onto fictional characters having an author's first name.

    Science.gov (United States)

    Barry, H

    2001-12-01

    Jane Austen projected some of her personality characteristics onto her fictional namesakes Jane Bennet in the novel Pride and Prejudice and Jane Fairfax in the novel Emma. Wishful fantasy seems satisfied by two attributes of both Janes. They are very beautiful, and they marry rich men they love. A feeling of inferiority was expressed by two attributes of both Janes, depicted as deficient in social communication and subordinate to the heroine of the novel.

  1. Outward Bound with Ayyappan: Work, Masculinity, and Self-Respect in a South Indian Pilgrimage Festival

    Directory of Open Access Journals (Sweden)

    Elizabeth (Liz Wilson

    2016-06-01

    Full Text Available The annual pilgrimage festival dedicated to the god Ayyappan has become immensely popular in the past sixty years. As many as fifty million pilgrims participate each year. This paper draws on interviews of pilgrims conducted in South India in 2012–2013. My fieldwork suggests that the increasing popularity of the event relates to the contemporary South Indian work environment, an environment in which traditional gender roles are being reshaped by the challenges posed by migration for work opportunities. Interviews of English-speaking pilgrims show that their interpretations of the pilgrimage festival highlight the complexities of manhood in a time of rapidly changing work roles for men and women. Specifically, my fieldwork demonstrates that pilgrims perceive Ayyappan as a source of aid for those who struggle to succeed as financial providers and heads of the family unit. Pilgrims anxious about the loss of traditional models of masculinity amidst rapid change find solace in the blessings the god Ayyappan yields.

  2. Evaluation on the Perception of the New Portable Set for Hajj Course (P.A.H.A.M) Based on Design Characteristics

    Science.gov (United States)

    Shahir Yahya, Mohd; Rahim, Abd Khalil Abd; Mohammad, Musli; Ibrahim, Mustaffa; Kadis, Ghazali

    2017-08-01

    This paper is about the perceptions of the pilgrims to the innovation of the portable training set for hajj course (P.A.H.A.M). The acronym P.A.H.A.M come from the Malay word “Praktikal Haji Mudahalih” as a tool in helping the hajj and umrah pilgrims to better understand the concept while doing the hajj and umrah practical. In Malaysia, one of the managing bodies of pilgrimage for Muslims in is Pilgrims Fund Board. It provides a series of courses every year to help in boosting the understanding of the pilgrims before leaving for the Holy Land. During the practical session, they will provide the replica model to help pilgrims to familiarise themselves with the actual situation in Mecca. However, the current replica model was built using an iron structure that is relatively heavy, not portable and embarks more cost of transportation and labour. Therefore, this paper discusses the perceptions of the pilgrims on the characteristics of Portable Training Set for Hajj Course (P.A.H.A.M) compared to the existing set in order to increase the understanding of pilgrims. A total of 53 samples of hajj and umrah pilgrims participated in this study consisted of the general public. From the data analysed using Statistical Software for Social Sciences (SPSS v19), the results of the survey showed that more than 90% of respondents agreed that this portable training set meets the characteristics such as easy to handle, more safety in crowd, portable, stability, light weight, suitable in-door and out-door activity, easy to clean, and more structured with average score 4.00 (agreed) and above. In conclusion, it is expected that this Portable Training Set for Hajj Course (P.A.H.A.M) can be used by Muslim’s communities in Malaysia particularly and Muslim countries in general to better understand the hajj and umrah activities before leaving to the Holy Land.

  3. Feasibility of high temporal resolution breast DCE-MRI using compressed sensing theory.

    Science.gov (United States)

    Wang, Haoyu; Miao, Yanwei; Zhou, Kun; Yu, Yanming; Bao, Shanglian; He, Qiang; Dai, Yongming; Xuan, Stephanie Y; Tarabishy, Bisher; Ye, Yongquan; Hu, Jiani

    2010-09-01

    To investigate the feasibility of high temporal resolution breast DCE-MRI using compressed sensing theory. Two experiments were designed to investigate the feasibility of using reference image based compressed sensing (RICS) technique in DCE-MRI of the breast. The first experiment examined the capability of RICS to faithfully reconstruct uptake curves using undersampled data sets extracted from fully sampled clinical breast DCE-MRI data. An average approach and an approach using motion estimation and motion compensation (ME/MC) were implemented to obtain reference images and to evaluate their efficacy in reducing motion related effects. The second experiment, an in vitro phantom study, tested the feasibility of RICS for improving temporal resolution without degrading the spatial resolution. For the uptake-curve reconstruction experiment, there was a high correlation between uptake curves reconstructed from fully sampled data by Fourier transform and from undersampled data by RICS, indicating high similarity between them. The mean Pearson correlation coefficients for RICS with the ME/MC approach and RICS with the average approach were 0.977 +/- 0.023 and 0.953 +/- 0.031, respectively. The comparisons of final reconstruction results between RICS with the average approach and RICS with the ME/MC approach suggested that the latter was superior to the former in reducing motion related effects. For the in vitro experiment, compared to the fully sampled method, RICS improved the temporal resolution by an acceleration factor of 10 without degrading the spatial resolution. The preliminary study demonstrates the feasibility of RICS for faithfully reconstructing uptake curves and improving temporal resolution of breast DCE-MRI without degrading the spatial resolution.

  4. Radiation-induced conductivity of doped silicon in response to photon, proton and neutron irradiation

    International Nuclear Information System (INIS)

    Kishimoto, N.; Amekura, H.; Plaksin, O.A.; Stepanov, V.A.

    2000-01-01

    The opto-electronic performance of semiconductors during reactor operation is restricted by radiation-induced conductivity (RIC) and the synergistic effects of neutrons/ions and photons. The RICs of Si due to photons, protons and pulsed neutrons have been evaluated, aiming at radiation correlation. Protons of 17 MeV with an ionizing dose rate of 10 3 Gy/s and/or photons (hν=1.3 eV) were used to irradiate impurity-doped Si (2x10 16 B atoms/cm 3 ) at 300 and 200 K. Proton-induced RIC (p-RIC) and photoconductivity (PC) were intermittently detected in an accelerator device. Neutron-induced RIC (n-RIC) was measured for the same Si in a pulsed fast-fission reactor, BARS-6, with a 70-μs pulse of 2x10 12 n/cm 2 (E>0.01 MeV) and a dose rate of up to 6x10 5 Gy/s. The neutron irradiation showed a saturation tendency in the flux dependence at 300 K due to the strong electronic excitation. Normalization of the electronic excitation, including the pulsed regime, gave a fair agreement among the different radiation environments. Detailed comparison among PC, p-RIC and n-RIC is discussed in terms of radiation correlation including the in-pile condition

  5. Cold comfort at the Magh Mela: social identity processes and physical hardship.

    Science.gov (United States)

    Pandey, Kavita; Stevenson, Clifford; Shankar, Shail; Hopkins, Nicholas P; Reicher, Stephen D

    2014-12-01

    Humans inhabit environments that are both social and physical, and in this article we investigate if and how social identity processes shape the experience and negotiation of physically demanding environmental conditions. Specifically, we consider how severe cold can be interpreted and experienced in relation to group members' social identity. Our data comprise ethnographic observation and semi-structured interviews with pilgrims attending a month-long winter Hindu religious festival that is characterized by near-freezing conditions. The analysis explores (1) how pilgrims appraised the cold and how these appraisals were shaped by their identity as pilgrims; (2) how shared identity with other pilgrims led to forms of mutual support that made it easier to cope with the cold. Our findings therefore extend theorizing on social identity processes to highlight their relevance to physical as well as social conditions. © 2013 The British Psychological Society.

  6. Pilgrimages of Teachers and Students of Ecclesiastical Academies to the Holy Land and the Holy Mt. Athos

    Directory of Open Access Journals (Sweden)

    Sukhova Nataliia

    2010-12-01

    Full Text Available The author deals with pilgrim trips to the Holy Places — the Holy Land and the Holy Mt. Athos, — which were undertaken by teachers and students of Russian orthodox ecclesiastical academies in 1870-1910. The article covers the cases of these pilgrim trips. The author analyzes the motivation of concrete pilgrims and the significance of trips for a Russian ecclesiastical school. Besides, the author pays attention to efforts of spiritually-educational community to find the importance of the Holy Places for theological and ecclesiastical-historical sciences.

  7. Representação sonora entre literatura e cinema: A questão do ponto de escuta nas adaptações de Persuasão de Jane Austen

    Directory of Open Access Journals (Sweden)

    Fernando Morais Da Costa

    2013-12-01

    Full Text Available http://dx.doi.org/10.5007/2175-8026.2013n65p185   Explorar a representação sonora pela literatura e em adaptações de obras literárias para o cinema. Analisar a representação de ambientes sonoros, da relação dos personagens com tais ambientes e os processos de identificação entre espectador e personagem, especialmente pelas nuances possíveis do ponto de escuta. Entendemos neste artigo que analisar a identificação entre espectador e personagem através da construção do ponto de escuta é tratar de um procedimento narrativo pouco analisado tanto no campo dos estudos literários quanto na teoria cinematográfica. Para tanto, a análise das adaptações cinematográficas dos romances de Jane Austen terá papel central, embora haja no decorrer do texto exemplos outros.

  8. Protective effect of remote limb ischemic perconditioning on the liver grafts of rats with a novel model.

    Directory of Open Access Journals (Sweden)

    Junjun Jia

    Full Text Available Remote ischemic conditioning (RIC is a known manual conditioning to decrease ischemic reperfusion injury (IRI but not increase ischemic time. Here we tried to establish a rat RIC model of liver transplantation (LT, optimize the applicable protocols and investigate the protective mechanism.The RIC model was developed by a standard tourniquet. Sprague-Dawley rats were assigned randomly to the sham operated control (N, standard rat liver transplantation (OLT and RIC groups. According to the different protocols, RIC group was divided into 3 subgroups (10 min×3, n = 6; 5 min×3, n = 6; 1 min×3, n = 6 respectively. Serum transaminases (ALT, AST, creatine kinase (CK, histopathologic changes, malondialdehyde (MDA, myeloperoxidase (MPO and expressions of p-Akt were evaluated.Compared with the OLT group, the grafts subjected to RIC 5min*3 algorithm showed significant reduction of morphological damage and improved the graft function. Also, production of reactive oxygen species (MDA and neutrophil accumulation (MPO were markedly depressed and p-Akt was upregulated.In conclusion, we successfully established a novel model of RIC in rat LT, the optimal RIC 5min*3 algorithm seemed to be more efficient to alleviate IRI of the liver graft in both functional and morphological categories, which due to its antioxidative, anti-inflammation activities and activating PI3K Akt pathway.

  9. Effectiveness and safety of endoscopic radial incision and cutting for severe benign anastomotic stenosis after surgery for colorectal carcinoma: a three-case series.

    Science.gov (United States)

    Asayama, Naoki; Nagata, Shinji; Shigita, Kenjiro; Aoyama, Taiki; Fukumoto, Akira; Mukai, Shinichi

    2018-03-01

    Benign colonic anastomotic stenosis sometimes occurs after surgical resection and usually requires surgical or endoscopic dilation. Limited data are available on the effectiveness and safety of the endoscopic radial incision and cutting (RIC) method at sites other than the esophagus. The aim of this retrospective study was to investigate the effectiveness and safety of RIC dilation for severe benign anastomotic colonic stenosis. Subjects were 3 men (median age 72 years, range 65 - 76 years) who developed severe benign anastomotic stenosis after surgical resection for colorectal carcinoma and were subsequently treated by RIC dilation at Hiroshima City Asa Citizens Hospital between May 2014 and December 2016. Severe anastomotic stenosis was defined as a narrowed anastomosis through which a standard colonoscope could not be passed. The median interval from surgery to RIC was 21 months (range 9 - 29 months). RIC was successful in all 3 patients and reduced the severity of dyschezia postoperatively; 2 patients experienced improvement after a single RIC session and the other after 6 RIC sessions. No treatment-related adverse events or re-stenosis requiring repeat dilation was noted during a median follow-up of 27 months (range 8 - 37 months). Our findings indicate that the RIC technique can be applied safely and effectively to various sites in the colon, avoiding the need for reoperation.

  10. The simplicial Ricci tensor

    International Nuclear Information System (INIS)

    Alsing, Paul M; McDonald, Jonathan R; Miller, Warner A

    2011-01-01

    The Ricci tensor (Ric) is fundamental to Einstein's geometric theory of gravitation. The three-dimensional Ric of a spacelike surface vanishes at the moment of time symmetry for vacuum spacetimes. The four-dimensional Ric is the Einstein tensor for such spacetimes. More recently, the Ric was used by Hamilton to define a nonlinear, diffusive Ricci flow (RF) that was fundamental to Perelman's proof of the Poincare conjecture. Analytic applications of RF can be found in many fields including general relativity and mathematics. Numerically it has been applied broadly to communication networks, medical physics, computer design and more. In this paper, we use Regge calculus (RC) to provide the first geometric discretization of the Ric. This result is fundamental for higher dimensional generalizations of discrete RF. We construct this tensor on both the simplicial lattice and its dual and prove their equivalence. We show that the Ric is an edge-based weighted average of deficit divided by an edge-based weighted average of dual area-an expression similar to the vertex-based weighted average of the scalar curvature reported recently. We use this Ric in a third and independent geometric derivation of the RC Einstein tensor in arbitrary dimensions.

  11. The simplicial Ricci tensor

    Science.gov (United States)

    Alsing, Paul M.; McDonald, Jonathan R.; Miller, Warner A.

    2011-08-01

    The Ricci tensor (Ric) is fundamental to Einstein's geometric theory of gravitation. The three-dimensional Ric of a spacelike surface vanishes at the moment of time symmetry for vacuum spacetimes. The four-dimensional Ric is the Einstein tensor for such spacetimes. More recently, the Ric was used by Hamilton to define a nonlinear, diffusive Ricci flow (RF) that was fundamental to Perelman's proof of the Poincarè conjecture. Analytic applications of RF can be found in many fields including general relativity and mathematics. Numerically it has been applied broadly to communication networks, medical physics, computer design and more. In this paper, we use Regge calculus (RC) to provide the first geometric discretization of the Ric. This result is fundamental for higher dimensional generalizations of discrete RF. We construct this tensor on both the simplicial lattice and its dual and prove their equivalence. We show that the Ric is an edge-based weighted average of deficit divided by an edge-based weighted average of dual area—an expression similar to the vertex-based weighted average of the scalar curvature reported recently. We use this Ric in a third and independent geometric derivation of the RC Einstein tensor in arbitrary dimensions.

  12. Islam, Jews and Eastern Christianity in late medieval pilgrims’ guidebooks: some examples from the Franciscan Convent of Mount Sion

    NARCIS (Netherlands)

    Campopiano, M.

    2012-01-01

    The Holy Land was described, not just in the accounts of the pilgrims who visited the most sacred land of Christianity, but also in several compilations and collections of texts conceived as guidebooks for clerics and pilgrims. From the fourteenth century onwards, many of these collections are

  13. The International River Interface Cooperative: Public Domain Software for River Flow and Morphodynamics (Invited)

    Science.gov (United States)

    Nelson, J. M.; Shimizu, Y.; McDonald, R.; Takebayashi, H.

    2009-12-01

    The International River Interface Cooperative is an informal organization made up of academic faculty and government scientists with the goal of developing, distributing and providing education for a public-domain software interface for modeling river flow and morphodynamics. Formed in late 2007, the group released the first version of this interface (iRIC) in late 2009. iRIC includes models for two and three-dimensional flow, sediment transport, bed evolution, groundwater-surface water interaction, topographic data processing, and habitat assessment, as well as comprehensive data and model output visualization, mapping, and editing tools. All the tools in iRIC are specifically designed for use in river reaches and utilize common river data sets. The models are couched within a single graphical user interface so that a broad spectrum of models are available to users without learning new pre- and post-processing tools. The first version of iRIC was developed by combining the USGS public-domain Multi-Dimensional Surface Water Modeling System (MD_SWMS), developed at the USGS Geomorphology and Sediment Transport Laboratory in Golden, Colorado, with the public-domain river modeling code NAYS developed by the Universities of Hokkaido and Kyoto, Mizuho Corporation, and the Foundation of the River Disaster Prevention Research Institute in Sapporo, Japan. Since this initial effort, other Universities and Agencies have joined the group, and the interface has been expanded to allow users to integrate their own modeling code using Executable Markup Language (XML), which provides easy access and expandability to the iRIC software interface. In this presentation, the current components of iRIC are described and results from several practical modeling applications are presented to illustrate the capabilities and flexibility of the software. In addition, some future extensions to iRIC are demonstrated, including software for Lagrangian particle tracking and the prediction of

  14. Dynamics of the Cult of Sheik Hussein of Bale, Ethiopia: Its Course ...

    African Journals Online (AJOL)

    It has immense potential for tourism that fascinates even the pilgrims, involving tour of scenic landscapes, famous shrines and singing in honor of the saint and Allah. However, due to the proliferation of extremist teachings of the Salafists and Wahabbists, attacks on pilgrims and marginalization of adherents have been ...

  15. Electrical Conductivity of Gamma Irradiated Aqueous Urea Solution and its Application for Determination of Absorbed Radiation Dose; Sife-Eldeen Dosimeter

    International Nuclear Information System (INIS)

    Sife- Eldeen, Kh.A.

    2008-01-01

    In This Study, the radiation induced electrical conductivity (RIC) of aqueous urea solutions was investigated after gamma radiolysis. It was found that the RIC depends on preirradiation urea concentration, absorbed radiation dose and storage time. At the same absorbed dose, RIC increases as preirradiation urea concentration increases. The RIC change of aqueous urea solutions reaches a maximum value at 3.5 M aqueous urea solutions. RIC of 0.133 and 3.5 M aqueous urea solutions as a function of dose, have been investigated in the range between 2.18 and 119.4 kGy. RIC of the 0.133 and 3.5 M aqueous urea solutions increased linearly with increasing dose (R 2 =0.9963, 0.9972 respectively). The calibration factors was found to be 2.1448 and 9.53 μS/kGy for sets with 0.133 and 3.5 M urea respectively .The coefficient of variation CV %, associated with RIC measurement of 3.5 M aqueous urea solution as a function of absorbed radiation dose was found to be 1.8025% and the uncertainty was found to be 3.6 % and 5.4 % for 95 % and 99 % confidence levels, respectively. The effective atomic number of 3.5 M aqueous urea solutions is 6.58, which indicates tissue equivalency of this system. The RIC values of 3.5 M aqueous urea solutions were found to be relatively stable over storage period of three weeks at 0 degree C. Accordingly, this system could be considered as a promising radiation-sensitive material for dosimetry of gamma rays in both technical and research fields

  16. Allogeneic Hematopoietic Cell Transplantation for Dyskeratosis Congenita: A Report of 3 Cases.

    Science.gov (United States)

    Tamura, Shinichi; Imamura, Toshihiko; Urata, Takayo; Kobayashi, Miki; Gen, Mari; Tomii, Toshihiro; Do, Junko; Osone, Shinya; Ishida, Hiroyuki; Hosoi, Hajime; Kuroda, Hiroshi

    2017-10-01

    Although bone marrow failure in patients with dyskeratosis congenita (DKC) can be successfully treated with allogeneic hematopoietic cell transplantation (allo-HCT) using a reduced intensity conditioning (RIC) regimen, the outcome of nonhematological disorders in patients with DKC treated with allo-HCT using RIC has not been fully elucidated. Here, we describe the clinical course of nonhematological disorders after allo-HCT with RIC in 3 consecutive patients with DKC. Allo-HCT with RIC was feasible in all cases; however, patient 1 developed lethal pulmonary disease and patient 2 experienced progression of hepatic fibrosis. Careful follow-up of patient-specific complications is required after allo-HCT in patients with DKC.

  17. Remote ischemic conditioning improves coronary microcirculation in healthy subjects and patients with heart failure

    Directory of Open Access Journals (Sweden)

    Kono Y

    2014-08-01

    Full Text Available Yasushi Kono,1 Shota Fukuda,1 Akihisa Hanatani,2 Koki Nakanishi,2 Kenichiro Otsuka,2 Haruyuki Taguchi,1 Kenei Shimada2 1Department of Medicine, Osaka Ekisaikai Hospital, Osaka, Japan; 2Department of Internal Medicine and Cardiology, Osaka City University School of Medicine, Osaka, Japan Background: Remote ischemic conditioning (RIC is a treatment modality that suppresses inflammation and improves endothelial function, which are factors involved in the pathogenesis of heart failure (HF with reduced left ventricular ejection fraction. Coronary flow reserve (CFR is a physiological index of coronary microcirculation and is noninvasively measured by transthoracic Doppler echocardiography (TTDE. This study aimed to investigate the effects of RIC on CFR in healthy subjects and patients with HF, through the assessment by TTDE. Methods: Ten patients with HF with left ventricular ejection fraction of less than 40%, and ten healthy volunteers were enrolled in this study. RIC treatment was performed twice a day for 1 week. Our custom-made RIC device was programmed to automatically conduct 4 cycles of 5 minutes inflation and 5 minutes deflation of a blood pressure cuff to create intermittent arm ischemia. CFR measurements and laboratory tests were examined before, and after 1 week of RIC treatment. Results: One week of RIC treatment was well tolerated in both groups. RIC treatment increased CFR from 4.0±0.9 to 4.6±1.3 (mean ± standard deviation in healthy subjects (P=0.02, and from 1.9±0.4 to 2.3±0.7 in patients with HF (P=0.03, respectively. Systolic blood pressure in healthy subjects, and heart rate in HF patients decreased after RIC treatment (both P<0.01. Conclusion: This study demonstrated that a 1 week course of RIC treatment improved coronary microcirculation in healthy subjects and patients with HF associated with reduced left ventricular ejection fraction. Keyword: echocardiography, coronary flow reserve, heart failure, preconditioning

  18. Être parasité par les fictions des autres. Rôle et (impertinence du personnage de Gabriel Rivages dans la trilogie 1984 d’Éric Plamondon

    Directory of Open Access Journals (Sweden)

    René Audet

    2015-01-01

    Full Text Available Romans fragmentaires autant que romans duels, les trois tomes de la trilogie 1984 d’Éric Plamondon associent chacun à une figure américaine (Weissmuller, Brautigan, Jobs le personnage de Gabriel Rivages, dont le destin est placé en écho à ces mythes. Singulier dans son histoire, Rivages reste toutefois un personnage faible, jouant un rôle de relais et de faire-valoir. Son actantialité réduite pourrait être perçue, à la lumière de la fragmentation romanesque et de l’architecture livresque de cet ensemble, comme le signal d’une individualité tiraillée entre la grandeur du réel mythifié et la faiblesse de la fiction ordinaire. As much fragmentary novels as they are dual novels, each of the three volumes of Eric Plamondon’s 1984 trilogy associates the character Gabriel Rivages with an American figure (Weissmuller, Brautigan, Jobs, placing the destiny of the character as an echo to the myths surrounding each figure. Though unique within his story, Rivages nevertheless remains a weak character, playing the role of relay or foil. His reduced actantiality may be perceived, in light of the novelistic fragmentation and the architecture of the trilogy, as the signal of an individuality caught between the grandeur of a mythologized reality and the feebleness of ordinary fiction.

  19. Radiation-Induced Carotid Artery Stenosis in a Patient with Carcinoma of the Oral Floor

    Directory of Open Access Journals (Sweden)

    Kahori Seto

    2013-01-01

    Full Text Available Radiation-induced carotid artery stenosis (RI-CS, a life-threatening condition, can occur after external radiation for head and neck cancer. We here describe a case of asymptomatic RI-CS in a 73-year-old patient treated with chemoradiotherapy and radical neck dissection for a basaloid squamous cell carcinoma of the oral floor. Stenosis of the left carotid artery, diagnosed as RI-CS, showed on an MRI performed 1.5 years after radiotherapy. Blood from the left side of the anterior cerebral artery and the middle anterior artery was flowing to the brain through the anterior and posterior communicating arteries, so no stent surgery or other treatment was necessary. The cancer has not recurred during approximately 5 years of followup after radiotherapy, and the patient has had no adverse effects from the RI-CS since it was diagnosed 3.5 years ago. This case emphasizes the necessity of early scrutiny for RI-CS in patients given radiotherapy for oral cancer.

  20. Expansion of donor-reactive host T cells in primary graft failure after allogeneic hematopoietic SCT following reduced-intensity conditioning.

    Science.gov (United States)

    Koyama, M; Hashimoto, D; Nagafuji, K; Eto, T; Ohno, Y; Aoyama, K; Iwasaki, H; Miyamoto, T; Hill, G R; Akashi, K; Teshima, T

    2014-01-01

    Graft rejection remains a major obstacle in allogeneic hematopoietic SCT following reduced-intensity conditioning (RIC-SCT), particularly after cord blood transplantation (CBT). In a murine MHC-mismatched model of RIC-SCT, primary graft rejection was associated with activation and expansion of donor-reactive host T cells in peripheral blood and BM early after SCT. Donor-derived dendritic cells are at least partly involved in host T-cell activation. We then evaluated if such an expansion of host T cells could be associated with graft rejection after RIC-CBT. Expansion of residual host lymphocytes was observed in 4/7 patients with graft rejection at 3 weeks after CBT, but in none of the 17 patients who achieved engraftment. These results suggest the crucial role of residual host T cells after RIC-SCT in graft rejection and expansion of host T cells could be a marker of graft rejection. Development of more efficient T cell-suppressive conditioning regimens may be necessary in the context of RIC-SCT.

  1. Modulation of functionally localized right insular cortex activity using real-time fMRI-based neurofeedback

    Directory of Open Access Journals (Sweden)

    Brian D Berman

    2013-10-01

    Full Text Available The capacity for subjects to learn to volitionally control localized brain activity using neurofeedback is actively being investigated. We aimed to investigate the ability of healthy volunteers to quickly learn to use visual feedback during real-time functional MRI (rtfMRI to modulate brain activity within their anterior right insular cortex (RIC localized during a blink suppression task, an approach of possible interest in the use of rtfMRI to reduce urges. The RIC region of interest (RIC-ROI was functionally localized using a blink suppression task, and BOLD signal changes within RIC-ROI used to create a constantly updating display fed back to the subject in the scanner. Subjects were instructed to use emotional imagery to try and increase activity within RIC-ROI during four feedback training runs (FB1–FB4. A ‘control’ run (CNTRL before training and a ‘transfer’ run (XSFR after training were performed without feedback to assess for baseline abilities and learning effects. Fourteen participants completed all neurofeedback training runs. At the group level, increased BOLD activity was seen in the anterior RIC during all the FB runs, but a significant increase in the functionally defined RIC-ROI was only attained during FB2. In atlas-defined insular cortex ROIs, significant increases were seen bilaterally during the CNTRL, FB1, FB2, and FB4 runs. Increased activity within the insular cortices did not show lateralization. Training did, however, result in a significant increase in functional connectivity between the RIC-ROI and the medial frontal gyrus when comparing FB4 to FB1. Since neurofeedback training did not lead to an increase in BOLD signal across all feedback runs, we suggest that learning to control one’s brain activity in this fashion may require longer or repeated rtfMRI training sessions.

  2. A comparative assessment of the curative potential of reduced intensity allografts in acute myeloid leukaemia

    DEFF Research Database (Denmark)

    Russell, N H; Kjeldsen, L; Craddock, C

    2015-01-01

    was to determine which approach improved survival and within which prespecified cytogenetic groups. RIC transplants significantly reduced relapse (adjusted hazard ratio (HR) 0.66 (0.50-0.85), P=0.002) compared to chemotherapy The 5-year overall survival from a sibling RIC (61%) was superior to a MUD RIC (37......%; adjusted HR 1.50 (1.01-2.21), P=0.04) due to lower NRM (34 vs 14%, P=0.002) In adjusted analyses, there was a survival benefit for sibling RIC over chemotherapy (59 vs 49%, HR 0.75 (0.57-0.97), P=0.03), with consistent results in intermediate and adverse-risk patients. In patients aged 35-44 years, best...

  3. Survival benefits of remote ischemic conditioning in sepsis.

    Science.gov (United States)

    Joseph, Bellal; Khalil, Mazhar; Hashmi, Ammar; Hecker, Louise; Kulvatunyou, Narong; Tang, Andrew; Friese, Randall S; Rhee, Peter

    2017-06-01

    Sepsis remains the leading cause of death in the surgical intensive care unit. Prior studies have demonstrated a survival benefit of remote ischemic conditioning (RIC) in many disease states. The aim of this study was to determine the effects of RIC on survival in sepsis in an animal model and to assess alterations in inflammatory biochemical profiles. We hypothesized that RIC alters inflammatory biochemical profiles resulting in decreased mortality in a septic mouse model. Eight to 12 week C57BL/6 mice received intra-peritoneal injection of 12.5-mg/kg lipopolysaccharide (LPS). Septic animals in the experimental group underwent RIC at 0, 2, and 6 h after LPS by surgical exploration and alternate clamping of the femoral artery. Six 4-min cycles of ischemia-reperfusion were performed. Primary outcome was survival at 5-d after LPS injection. Secondary outcome was to assess the following serum cytokine levels: interferon-γ (IFN-γ), interleukin (IL)-10, IL-1β, and tumor necrosis factoralpha (TNFα) at the baseline before LPS injection, 0 hour after LPS injection, and at 2, 4, 24 hours after induction of sepsis (RIC was performed at 2 h after LPS injection). Kaplan-Meier survival analysis and log-rank test were used. ANOVA test was used to compare cytokine measurements. We performed experiments on 44 mice: 14 sham and 30 RIC mice (10 at each time point). Overall survival was higher in the experimental group compared to the sham group (57% versus 21%; P = 0.02), with the highest survival rate observed in the 2-hour post-RIC group (70%). On Kaplan-Meier analysis, 2-h post-RIC group had increased survival at 5 days after LPS (P = 0.04) with hazard ratio of 0.3 (95% confidence interval = 0.09-0.98). In the RIC group, serum concentrations of IFN-γ, IL-10, IL-1β, and TNFα peaked at 2 h after LPS and then decreased significantly over 24 hours (P sepsis and has the potential for implementation in the clinical practice. Early implementation of RIC may play an

  4. Retrospective audit of the investigation of patients with suspected acute subarachnoid haemorrhage

    International Nuclear Information System (INIS)

    Muhammed, O.; Teubnet, D.; Jones, D.N.; Slavotinek, J.P.

    2010-01-01

    Recommended investigational care (RIC) of emergency department (ED) patients with suspected subarachnoid haemorrhage comprises lumbar puncture (LP) to detect xanthochromia if the preceding CT scan is negative. Retrospective audit of the investigational care of 100 consecutive ED patients presenting with possible subarachnoid haemorrhage. Of the 100 patients, 91 had negative CT, and 36 (39.6%) of these patients had an LP performed to detect xanthochromia (i.e. RIC). Fifty-five of 91 (60.4%) patients did not receive RIC. Of the 55 patients who did not receive RIC, 25 (45.5%) had a documented senior clinical decision not to perform an LP; 15 (27.3%) had no documented reason; five (9.1%) refused consent; two (3.6%) had an LP but no xanthochromia requested, one patient did not have an LP because of technical issues, six patients underwent CT angiography (CTA), and one patient underwent magnetic resonance angiography (MRA), in the absence of a LP, following a negative CT. Two patients underwent CTA following a negative xanthochromia result. Patients admitted to the emergency extended care unit had 6.85 times the odds of receiving RIC (95% CI 2.20-21.4). Fifty-five (55) of 91 (60%) ED patients did not receive RIC. Fifteen of the 55 did not have any documented justification for not performing an LP with xanthochromia testing. Admission to an emergency extended care unit was a predictor of receiving RIC. Inappropriate use of CTA and MRA was identified. These findings have important implications for patient safety. Multifaceted strategies are required to close this evidence-practice gap.

  5. Tempering an Enlightened Educator: Frédéric-César de La Harpe at the Russian Imperial Court (1783–1795

    Directory of Open Access Journals (Sweden)

    Andrei Yu. Andreev

    2017-12-01

    Full Text Available Among all the educators who cared for him from his early childhood, Alexander I gave a particular honor to only one, the Swiss teacher Frédéric-César de La Harpe (1754–1838, who, invited to teach the French language, was further his instructor in geography, history, arithmetic, and geometry, as well as the foundations of philosophy. This Swiss teacher has been regarded in historical studies as the fortunate “chosen one” by Catherine II, who summoned him to direct Alexander’s education and who rewarded him accordingly afterwards. The present article peers into the backstage of the long educational process (1783–1795 in which he was engaged, revealing the less idyllic facts. Based on unpublished documents in Russian and Swiss archives, this study presents a picture of the place of an educator on the main stage of his activity, the Russian Imperial court, and thus the interplay of the history of practice and of ideas and their representations. Did La Harpe himself choose to work as an educator? Did Catherine II really search and find the Swiss teacher for his abilities? Did his teaching indeed represent a concretization of Catherine’s thoughts on this matter? And finally, how did La Harpe himself estimate his situation at the court, which was transformed into a “success story” only after 1814? This article, offering some answers to these questions, adds to the analysis the different circumstances of La Harpe’s appearance and later life at the court; the difficulties he faced in spite of the support of Catherine II, which was, regrettably, withdrawn unexpectedly; and, finally, the permanent discrepancies between his pedagogical ideals and the everyday studies in which he engaged.

  6. The diagnosis of cerebrospinal fluid hypovolemia. The comparison between CT myelography and RI cisternography

    International Nuclear Information System (INIS)

    Watanabe, Keisuke; Hashizume, Keiji; Inoue, Satoki; Fujiwara, Aki; Furuya, Hitoshi

    2008-01-01

    The comparison in the title is performed in cases with suspicious hypovolemia of cerebrospinal fluid (CSF) and its leak at the lumbar region is also examined in whiplash injury. Subjects are 25 cases (M 14/F 11, av. age 36.9 y) with traffic (13 cases), whiplash (4) and null (8) injuries. CT myelography (CTM) is conducted by injection of iotrolan through the lumbar puncturing needle to get 700 images of the whole spine of 1 mm slice thickness, which after animated, are observed visually. RI cisternography (RIC) is done immediately, 2 and 24 hr after injection of 10 MBq of diethylenetriamine pentaacetic acid (DTPA)-In through the puncturing needle. In 15 cases exhibiting positive RIC findings, CTM gives a positive leak at cervical and thoracic regions only in 2 cases and a false positive in other 13. In contrast, RIC fails to detect 2 cases of 4 with a leak at cervical and thoracic regions. Thus RIC is less reliable, and often observable RI accumulation at the lumbar area in RIC is not always a leak. (R.T.)

  7. Reduced intensity versus full myeloablative stem cell transplant for advanced CLL.

    Science.gov (United States)

    Peres, E; Braun, T; Krijanovski, O; Khaled, Y; Levine, J E; Yanik, G; Kato, K; Mineishi, S

    2009-11-01

    CLL remains incurable with the standard therapy. Allogeneic hematopoietic stem cell transplant may be curative. We examined 50 patients with advanced CLL who underwent allogeneic HCT at the University of Michigan between 1996 and 2006. Twenty-one patients received reduced-intensity conditioning (RIC) and twenty-nine patients received full-intensity conditioning (FIC) consisting of CY, etoposide and BCNU (n=20) or BU and CY (n=9). RIC recipients were older than FIC recipients (median age 54 vs 51, P=0.009). There were no statistically significant differences between groups in terms of the number of earlier therapies or patients with adverse cytogenetics. There were more unrelated donors in the RIC group 62% than in the FIC group 31% (P=0.030). Despite their older age and greater use of URD, the 5-year overall survival (OS) rate was 63% in the RIC group as compared with 18% in the FIC group (P=0.006). The primary cause of inferior survival in the FIC recipients was TRM, which was twice as high at day 100 for the FIC group 27% compared with the RIC group 14% (P=0.005). The relapse rate was 15% regardless with the majority of relapses occurring after day 100. These results suggest a favorable outcome for advanced CLL who undergo a RIC regimen compared with FIC.

  8. 76 FR 5501 - Request for Comments: Review and Improvement of EDA's Regulations

    Science.gov (United States)

    2011-02-01

    ... creation and growth of Regional Innovation Clusters (RICs). In addition, EDA has identified potential... our stakeholders and the American people. 1. Regional Innovation Clusters (RICs) EDA supports the..., February 1, 2011 / Proposed Rules#0;#0; [[Page 5501

  9. 64Cu-Labeled Trastuzumab Fab-PEG24-EGF Radioimmunoconjugates Bispecific for HER2 and EGFR: Pharmacokinetics, Biodistribution, and Tumor Imaging by PET in Comparison to Monospecific Agents.

    Science.gov (United States)

    Kwon, Luke Yongkyu; Scollard, Deborah A; Reilly, Raymond M

    2017-02-06

    Heterodimerization of EGFR with HER2 coexpressed in breast cancer (BC) promotes tumor growth, and increased EGFR expression is associated with trastuzumab resistance. Our aim was to construct 64 Cu-labeled bispecific radioimmunoconjugates (bsRIC) composed of trastuzumab Fab, which binds HER2 linked through a polyethylene glycol (PEG 24 ) spacer to EGF, and to compare their pharmacokinetic, biodistribution, and tumor imaging characteristics by positron-emission tomography (PET). bsRICs were generated by linking maleimide modified trastuzumab Fab with thiolated EGF through a thioether bond. HER2 and EGFR binding were assessed in vitro in MDA-MB-231 (EGFR mod /HER2 low ), MDA-MB-468 (EGFR high /HER2 neg ), MDA-MB-231-H2N (EGFR mod /HER2 mod ), and SKOV3 (EGFR low /HER2 high ) cells by competition and saturation cell binding assays to estimate the dissociation constant (K d ). The elimination of the 64 Cu-NOTA-trastuzumab Fab-PEG 24 -EGF bsRICs from the blood of Balb/c mice was compared to monospecific 64 Cu-NOTA-trastuzumab Fab and 64 Cu-NOTA-EGF. MicroPET/CT imaging was performed in NOD/SCID mice bearing subcutaneous MDA-MB-468, MDA-MB-231/H2N, or SKOV3 human BC xenografts at 24 and 48 h postinjection (p.i.) of bsRICs. Tumor and normal tissue uptake were quantified by biodistribution studies and compared to monospecific agents. The binding of bsRICs to MDA-MB-231 cells was decreased to 24.5 ± 5.2% by excess EGF, while the binding of bsRICs to SKOV3 cells was decreased to 38.6 ± 5.4% by excess trastuzumab Fab, demonstrating specific binding to both EGFR and HER2. 64 Cu-labeled bsRICs incorporating the PEG 24 spacer were eliminated more slowly from the blood than 64 Cu-bsRICs without the PEG spacer and were cleared much more slowly than 64 Cu-NOTA-Fab or 64 Cu-NOTA-EGF. All three tumor xenografts were visualized by microPET/CT at 24 and 48 h p.i. of bsRICs. Biodistribution studies at 48 h p.i. in NOD/SCID mice with MDA-MB-231/H2N tumors demonstrated significantly

  10. A voltage-gated pore for translocation of tRNA

    Energy Technology Data Exchange (ETDEWEB)

    Koley, Sandip; Adhya, Samit, E-mail: nilugrandson@gmail.com

    2013-09-13

    Highlights: •A tRNA translocating complex was assembled from purified proteins. •The complex translocates tRNA at a membrane potential of ∼60 mV. •Translocation requires Cys and His residues in the Fe–S center of RIC6 subunit. -- Abstract: Very little is known about how nucleic acids are translocated across membranes. The multi-subunit RNA Import Complex (RIC) from mitochondria of the kinetoplastid protozoon Leishmania tropica induces translocation of tRNAs across artificial or natural membranes, but the nature of the translocation pore remains unknown. We show that subunits RIC6 and RIC9 assemble on the membrane in presence of subunit RIC4A to form complex R3. Atomic Force Microscopy of R3 revealed particles with an asymmetric surface groove of ∼20 nm rim diameter and ∼1 nm depth. R3 induced translocation of tRNA into liposomes when the pH of the medium was lowered to ∼6 in the absence of ATP. R3-mediated tRNA translocation could also be induced at neutral pH by a K{sup +} diffusion potential with an optimum of 60–70 mV. Point mutations in the Cys{sub 2}–His{sub 2} Fe-binding motif of RIC6, which is homologous to the respiratory Complex III Fe–S protein, abrogated import induced by low pH but not by K{sup +} diffusion potential. These results indicate that the R3 complex forms a pore that is gated by a proton-generated membrane potential and that the Fe–S binding region of RIC6 has a role in proton translocation. The tRNA import complex of L. tropica thus contains a novel macromolecular channel distinct from the mitochondrial protein import pore that is apparently involved in tRNA import in some species.

  11. Relaxation model of radiation-induced conductivity in polymers

    Science.gov (United States)

    Zhutayeva, Yu. R.; Khatipov, S. A.

    1999-05-01

    The paper suggests a relaxation model of radiation-induced conductivity (RIC) in polymers. According to the model, the transfer of charges generated in the polymer volume by ionizing radiation takes place with the participation of molecular relaxation processes. The mechanism of electron transport consists in the transfer of the charge directly between traps when they draw close to one another due to the rotation of macromolecule segments. The numerical solutions of the corresponding kinetic equations for different distribution functions Q( τ) of the times of molecular relaxation and for different functions of the probability P( τ, τ') of charge transfer in the `overlapping' regions of the diffusion spheres of the segments are analyzed. The relaxation model provides an explanation of the non-Arrhenius behavior of the RIC temperature dependence, the power dependence of RIC on the dose rate with a power index in the interval 0.5-1.0, the appearance of maxima in the curves of the RIC temporal dependence and their irreversible character in the region of large dose rates (more than 1 Gy/s). The model can be used for interpreting polymer RIC in conditions of kinetic mobility of macromolecules.

  12. Mapping Point-of-Purchase Influencers of Food Choice in Australian Remote Indigenous Communities

    Directory of Open Access Journals (Sweden)

    Joanna Henryks

    2016-02-01

    Full Text Available Closing the health gap between Indigenous and non-Indigenous Australians relies, in part, on addressing the poor levels of nutrition in remote Indigenous communities (RIC. This article identifies and maps key influencers of food choice at the point-of-purchase (POP in Australian RIC and identifies gaps in our knowledge. It is based on a narrative review of the literature pertaining to food in RIC from a range of disciplinary perspectives including nutrition, ethnography, public health, anthropology, and remote health to map POP drivers of food choice. In particular, the role of habit is identified as a key factor that has previously not been discussed in the literature. The conceptual framework can be used as a basis for future POP research in RIC and provides guidance for social marketers, public health, nutrition, and policy workers operating in this field.

  13. Mobilized peripheral blood stem cells compared with bone marrow from HLA-identical siblings for reduced-intensity conditioning transplantation in acute myeloid leukemia in complete remission

    DEFF Research Database (Denmark)

    Nagler, Arnon; Labopin, Myriam; Shimoni, Avichai

    2012-01-01

    Reduced-intensity conditioning (RIC)-alloSCT is increasingly used for acute myelogenous leukemia. Limited data are available for the comparison of peripheral blood stem cells with bone marrow for RIC-alloSCT. We used the European Group for Blood and Marrow Transplantation (EBMT) ALWP data...... to compare the outcome of mobilized peripheral blood stem cells (PBSC) (n = 1430) vs. bone marrow (BM) (n = 107) for acute myelogenous leukemia (AML) patients with complete remission that underwent RIC-alloSCT from compatible sibling donors. The leukemia features, the disease status, and the time from...

  14. Reduced-intensity conditioning lowers treatment-related mortality of allogeneic stem cell transplantation for chronic lymphocytic leukemia : a population-matched analysis

    NARCIS (Netherlands)

    Dreger, P; Brand, R; Milligan, D; Corradini, P; Finke, J; Deliliers, GL; Martino, R; Russell, N; van Biezen, A; Michallet, M; Niederwieser, D

    To elucidate whether reduced-intensity conditioning (RIC) decreases treatment-related mortality (TRM) after allogeneic stem cell transplantation (allo-SCT) for chronic lymphocytic leukemia (CLL), we retrospectively compared 73 RIC cases from a recent EBMT survey with 82 patients from the EBMT

  15. 78 FR 64293 - Proposed Collection; Comment Request

    Science.gov (United States)

    2013-10-28

    ... Investment Companies. OMB Number: 1545-1010. Form Number: 1120-RIC. Abstract: Internal Revenue Code sections... DEPARTMENT OF THE TREASURY Internal Revenue Service [Form 1120-RIC] Proposed Collection; Comment Request AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and request for comments. SUMMARY...

  16. 76 FR 76491 - Economic Development Administration Regulatory Revision

    Science.gov (United States)

    2011-12-07

    ... Regional Innovation Clusters or RICs to define this important economic development strategy. See proposed... definition to emphasize vertical integration while remaining flexible by defining RICs as ``networks of... Vol. 76 Wednesday, No. 235 December 7, 2011 Part II Department of Commerce Economic Development...

  17. Vaata ja kuula / Annika Koppel

    Index Scriptorium Estoniae

    Koppel, Annika

    2005-01-01

    Heliplaatidest: Jane Birkin "Randez-Vous", "Chill Brazili", "Jazzland Sampler 2005", Mylene Farmer "Avant Que L'Ombre". Norra ansamblist Jaga Jazzist (kontsert 15. juunil Pirita lillepaviljonis, soojendusesinejaks soome kitarrist Jarmo Saari). Jane Birkin esineb Tallinnas 29. juunil

  18. Tõendid praktikasse / Ere Uibu, Ester Öpik

    Index Scriptorium Estoniae

    Uibu, Ere

    2016-01-01

    Eesti Õdede Liidu konverentsil tunnustati meditsiiniõdesid Sirje Kõvermäge, Kadri Piiri, Evelyn Evertit, Ere Uibut, Jane Freimani, Reet Tohvret, Teija Toivarit, Jane Remmerit, Ülle Tammsaart, Lily Parmu ja Kätlin Lünekundu

  19. Controls on Turbulent Mixing in a Strongly Stratified and Sheared Tidal River Plume

    Energy Technology Data Exchange (ETDEWEB)

    Jurisa, Joseph T.; Nash, Jonathan D.; Moum, James N.; Kilcher, Levi F.

    2016-08-01

    Considerable effort has been made to parameterize turbulent kinetic energy (TKE) dissipation rate ..epsilon.. and mixing in buoyant plumes and stratified shear flows. Here, a parameterization based on Kunze et al. is examined, which estimates ..epsilon.. as the amount of energy contained in an unstable shear layer (Ri < Ric) that must be dissipated to increase the Richardson number Ri = N2/S2 to a critical value Ric within a turbulent decay time scale. Observations from the tidal Columbia River plume are used to quantitatively assess the relevant parameters controlling ..epsilon.. over a range of tidal and river discharge forcings. Observed ..epsilon.. is found to be characterized by Kunze et al.'s form within a factor of 2, while exhibiting slightly decreased skill near Ri = Ric. Observed dissipation rates are compared to estimates from a constant interfacial drag formulation that neglects the direct effects of stratification. This is found to be appropriate in energetic regimes when the bulk-averaged Richardson number Rib is less than Ric/4. However, when Rib > Ric/4, the effects of stratification must be included. Similarly, ..epsilon.. scaled by the bulk velocity and density differences over the plume displays a clear dependence on Rib, decreasing as Rib approaches Ric. The Kunze et al. ..epsilon.. parameterization is modified to form an expression for the nondimensional dissipation rate that is solely a function of Rib, displaying good agreement with the observations. It is suggested that this formulation is broadly applicable for unstable to marginally unstable stratified shear flows.

  20. Novel vaccination approach for dengue infection based on recombinant immune complex universal platform.

    Science.gov (United States)

    Kim, Mi-Young; Reljic, Rajko; Kilbourne, Jacquelyn; Ceballos-Olvera, Ivonne; Yang, Moon-Sik; Reyes-del Valle, Jorge; Mason, Hugh S

    2015-04-08

    Dengue infection is on the rise in many endemic areas of the tropics. Vaccination remains the most realistic strategy for prevention of this potentially fatal viral disease but there is currently no effective vaccine that could protect against all four known serotypes of the dengue virus. This study describes the generation and testing of a novel vaccination approach against dengue based on recombinant immune complexes (RIC). We modelled the dengue RIC on the existing Ebola RIC (Phoolcharoen, et al. Proc Natl Acad Sci USA 2011;108(Dec (51)):20695) but with a key modification that allowed formation of a universal RIC platform that can be easily adapted for use for other pathogens. This was achieved by retaining only the binding epitope of the 6D8 ant-Ebola mAb, which was then fused to the consensus dengue E3 domain (cEDIII), resulting in a hybrid dengue-Ebola RIC (DERIC). We expressed human and mouse versions of these molecules in tobacco plants using a geminivirus-based expression system. Following purification from the plant extracts by protein G affinity chromatography, DERIC bound to C1q component of complement, thus confirming functionality. Importantly, following immunization of mice, DERIC induced a potent, virus-neutralizing anti-cEDIII humoral immune response without exogenous adjuvants. We conclude that these self-adjuvanting immunogens have the potential to be developed as a novel vaccine candidate for dengue infection, and provide the basis for a universal RIC platform for use with other antigens. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Mental health in mass gatherings

    Directory of Open Access Journals (Sweden)

    Shahbaz Ali Khan

    2016-01-01

    Full Text Available Background: Hajj pilgrimage, in Saudi Arabia, is one of the world's largest religious mass gatherings. We have similar mass gathering scenarios in India such as the Amarnath Yatra and Kumbh. A unique combination of physical, physiological, and psychological factors makes this pilgrimage a very stressful milieu. We studied the emergence of psychopathology and its determinants, in this adverse environment in mass gathering situation, in Indian pilgrims on Hajj 2016. Materials and Methods: This is a descriptive study analyzing the mental morbidity in 1.36 lakh Indian pilgrims during Hajj 2016, using SPSS software version 19. Results: Totally 182 patients reported psychological problems. Twenty-two patients (12% required admission. Twelve (6.8% pilgrims reported a past history of a mental illness. One hundred and sixty-five (93.2% patients never had any mental symptoms earlier in life. The most common illnesses seen were stress related (45.7% followed by psychosis (9.8%, insomnia (7.3%, and mood disorders (5.6%. The most common symptoms recorded were apprehension (45%, sleep (55%, anxiety (41%, and fear of being lost (27%. Psychotropics were prescribed for 46% of pilgrims. All patients completed their Hajj successfully and returned to India. Conclusions: Cumulative stress causes full spectrum of mental decompensation, and prompt healing is aided by simple nonpharmacological measures including social support and counseling in compatible sociolinguistic milieu.

  2. Mental health in mass gatherings

    Science.gov (United States)

    Khan, Shahbaz Ali; Chauhan, V. S.; Timothy, A.; Kalpana, S.; Khanam, Shagufta

    2016-01-01

    Background: Hajj pilgrimage, in Saudi Arabia, is one of the world's largest religious mass gatherings. We have similar mass gathering scenarios in India such as the Amarnath Yatra and Kumbh. A unique combination of physical, physiological, and psychological factors makes this pilgrimage a very stressful milieu. We studied the emergence of psychopathology and its determinants, in this adverse environment in mass gathering situation, in Indian pilgrims on Hajj 2016. Materials and Methods: This is a descriptive study analyzing the mental morbidity in 1.36 lakh Indian pilgrims during Hajj 2016, using SPSS software version 19. Results: Totally 182 patients reported psychological problems. Twenty-two patients (12%) required admission. Twelve (6.8%) pilgrims reported a past history of a mental illness. One hundred and sixty-five (93.2%) patients never had any mental symptoms earlier in life. The most common illnesses seen were stress related (45.7%) followed by psychosis (9.8%), insomnia (7.3%), and mood disorders (5.6%). The most common symptoms recorded were apprehension (45%), sleep (55%), anxiety (41%), and fear of being lost (27%). Psychotropics were prescribed for 46% of pilgrims. All patients completed their Hajj successfully and returned to India. Conclusions: Cumulative stress causes full spectrum of mental decompensation, and prompt healing is aided by simple nonpharmacological measures including social support and counseling in compatible sociolinguistic milieu. PMID:28659703

  3. The impact of center experience on results of reduced intensity:allogeneic hematopoietic SCT for AML. An analysis from the Acute Leukemia Working Party of the EBMT

    DEFF Research Database (Denmark)

    Giebel, S; Labopin, M; Mohty, M

    2013-01-01

    Allogeneic hematopoietic SCT with reduced-intensity conditioning (RIC-HSCT) is increasingly adopted for the treatment of older adults with AML. Our goal was to verify for the first time, if center experience influences outcome of RIC-HSCT. Results of 1413 transplantations from HLA-matched related...

  4. Improved GFR and renal plasma perfusion following remote ischaemic conditioning in a porcine kidney transplantation model

    DEFF Research Database (Denmark)

    Krogstrup, Nicoline V; Soendergaard, Peter; Secher, Niels G

    2012-01-01

    Delayed graft function (DGF) complicates approximately 25% of kidney allografts donated after brain death (DBD). Remote ischaemic conditioning (rIC) involves brief, repetitive, ischaemia in a distant tissue in connection with ischaemia/reperfusion in the target organ. rIC has been shown to induce...

  5. Modulation of the stretch reflex arc to improve functional recovery after peripheral nerve injury

    OpenAIRE

    Arbat i Plana, Ariadna

    2016-01-01

    Després d'una lesió del sistema nerviós perifèric, aquest té la capacitat de regenerar però la seva recuperació funcional sol ser limitada, principalment degut a la inespecificitat de la reinnervació dels òrgans perifèrics i als canvis plàstics maladaptatius de la circuiteria espinal. En aquesta tesi hem volgut modular els canvis a la circuiteria espinal del reflex d'estirament per poder millorar la recuperació funcional després de lesions del nervi perifèric en un model animal. En primer llo...

  6. In vitro evaluation of resonance frequency analysis values to different implant contact ratio and stiffness of surrounding material.

    Science.gov (United States)

    Kwak, Mu-Seung; Kim, Seok-Gyu

    2013-11-01

    The present study was aimed to evaluate the influence of implant contact ratio and stiffness of implant-surrounding materials on the resonance frequency analysis (RFA) values. Seventy resin blocks that had the different amounts (100, 50, 30, 15%) of resin-implant contact (RIC) were fabricated. Ten silicone putty blocks with 100% silicone-implant contact were also made. The implants with Ø5.0 mm × 13.0 mm were placed on eighty specimen blocks. The RFA value was measured on the transducer that was connected to each implant by Osstell Mentor. Kruskal-Wallis and Scheffe's tests (α=.05) were done for statistical analysis. The control resin group with 100% RIC had the highest RFA value of 83.9, which was significantly different only from the resin group with 15% RIC among the resin groups. The silicone putty group with 100% contact had the lowest RFA value of 36.6 and showed statistically significant differences from the resin groups. Within the limitations of this in vitro study, there was no significant difference in the RFA values among the resin groups with different RIC's except when the RIC difference was more than 85%. A significant increase in the RFA value was observed related to the increase in stiffness of material around implant.

  7. AHP 45: REVIEW: AMNYE MACHEN MOUNTAIN CIRCUMAMBULATION

    Directory of Open Access Journals (Sweden)

    Bill Bleisch

    2017-03-01

    Full Text Available This sublime documentary was filmed by a Tibetan team in 2014, the Year of the Horse. The film features stunning visual images of sacred Amnye Machen presented with an ethereal soundtrack of Tibetanelectronica fusion. It also includes a large amount of information about the practices of pilgrimage, illustrated with valuable footage of pilgrims at prayer, or walking and prostrating along the kora route; interviews with pilgrims; and extended explanations by Tibetan scholar, Gonpo Lhachen, and Tibetan environmentalist, Tsering Bum.

  8. 76 FR 12415 - Proposed Collection; Comment Request for Regulation Project

    Science.gov (United States)

    2011-03-07

    ..., Certain Transfers of Property to Regulated Investment Companies (RICs) and Real Estate Investment Trusts... Property to Regulated Investment Companies (RICs) and Real Estate Investment Trusts (REITs). OMB Number... with respect to the net built-in gain of C corporation property that becomes property of a Regulated...

  9. La Inscripción Ibérica en escritura jonia, Serreta IX.

    OpenAIRE

    Silgo Gauche, Luís

    1997-01-01

    S’estudía una nova inscripció sobre làmina de plom, localitzada casualment en l’àrea del poblat ibèric de la Serreta (Alcoi, Cocentaina, Penàguila), en l’escriptura del qual es van emprar caracters greco-ibèrics.

  10. The Potential of the Republic of Korea Navy for Cooperation with the Japanese Maritime Self-Defense Force in the Security of Greater East Asia.

    Science.gov (United States)

    1985-06-01

    match for the United States’ F-4 series during confrontations in Vietnam. The North does have the "’Christopher F. Foss Jane’s Armour and Artillery...complimented Nakasone on being so different from previous Japanese P. M.’s who used, "soft and misty language.ŗ𔃻 Nakasone’s communicating skill was...in, 19657 * Foss, Christopher F. Jane’s Armour and Artillery 1984-85, 5th ed. London: Jane’s P-ublhislng, 19Z4. Francis, David R. "Budget Deficits

  11. Lungo le vie di pellegrinaggio: la lezione astronomica di Gerberto a San Michele della Chiusa

    Science.gov (United States)

    Paladino, Laura C.

    A pilgrim on the trails of the Earth: that's how Gerbertus appears to us in the years preceding his pontificate as well in those, brief and intense, in which he was Pope. An ardent pilgrim of faith moved at the same time by vast intellectual interests that allowed him to come into contact with the most important schools of the time, of any cultural tradition; a pilgrim full of love, willing to transmit the enormous heritage of faith and knowledge of which he was custodian. The presence of the illustrious Benedictine is not explicitly documented in the Abbey of San Michele della Chiusa, but the signs of its cultural and ideological influence are evident both in historical memory as in the artistical vestiges of the Sacra: we investigate here, this presence, authoritative, original and versatile, to outline another aspect, still little investigated, of the lesson of Gerbert, monk, scientist, teacher and pastor.

  12. GENERAL CHARACTERISTICS OF RELIGIOUS TOURISM IN CROATIA

    Directory of Open Access Journals (Sweden)

    Eddy Rot

    2014-06-01

    Full Text Available Croatia has a rich sacral (tangible and intangible heritage, which undoubtedly has great cultural value, and part of the religious heritage has been included in the World Heritage List of UNESCO. The fact is, however, that, except when it comes to top attractions, churches as tourist facilities, are poorly attended and do not get almost no direct tourism income.. In this paper, after the introductory explanations of basic terms related to religious tourism and pilgrimage, we explore the basic features of religious tourism in Croatia, both on tourist attractions, as well as on the tourist demand. It also presents the results of empirical research on the socio-demographic profile of the author, the role of religion in the life of pilgrims and the satisfaction of the visitors to the Shrine of Mary of Bistrica in 2013 among 50 pilgrims in Marija Bistrica. The main objective is to determine how the pilgrims perceived the tourism offer in religious tourism.

  13. Analysis of impulse oscillometric measures of lung function and respiratory system model parameters in small airway-impaired and healthy children over a 2-year period

    Directory of Open Access Journals (Sweden)

    Nava Pat

    2011-03-01

    Full Text Available Abstract Background Is Impulse Oscillometry System (IOS a valuable tool to measure respiratory system function in Children? Asthma (A is the most prevalent chronic respiratory disease in children. Therefore, early and accurate assessment of respiratory function is of tremendous clinical interest in diagnosis, monitoring and treatment of respiratory conditions in this subpopulation. IOS has been successfully used to measure lung function in children with a high degree of sensitivity and specificity to small airway impairments (SAI and asthma. IOS measures of airway function and equivalent electrical circuit models of the human respiratory system have been developed to quantify the severity of these conditions. Previously, we have evaluated several known respiratory models based on the Mead's model and more parsimonious versions based on fitting IOS data known as extended RIC (eRIC and augmented RIC (aRIC models have emerged, which offer advantages over earlier models. Methods IOS data from twenty-six children were collected and compared during pre-bronchodilation (pre-B and post- bronchodilation (post-B conditions over a period of 2 years. Results and Discussion Are the IOS and model parameters capable of differentiating between healthy children and children with respiratory system distress? Children were classified into two main categories: Healthy (H and Small Airway-Impaired (SAI. The IOS measures and respiratory model parameters analyzed differed consistently between H and SAI children. SAI children showed smaller trend of "growth" and larger trend of bronchodilator responses than H children. The two model parameters: peripheral compliance (Cp and peripheral resistance (Rp tracked IOS indices of small airway function well. Cp was a more sensitive index than Rp. Both eRIC and aRIC Cps and the IOS Reactance Area, AX, (also known as the "Goldman Triangle" showed good correlations. Conclusions What are the most useful IOS and model parameters? In

  14. Reduced intensity-conditioned allogeneic stem cell transplantation for multiple myeloma relapsing or progressing after autologous transplantation: a study by the European Group for Blood and Marrow Transplantation.

    NARCIS (Netherlands)

    Auner, H.W.; Szydlo, R.; Biezen, A. van; Iacobelli, S.; Gahrton, G.; Milpied, N.; Volin, L.; Janssen, J.; Nguyen Quoc, S.; Michallet, M.; Schoemans, H.; Cheikh, J. El; Petersen, E.; Guilhot, F.; Schonland, S.; Ahlberg, L.; Morris, C.; Garderet, L.; Witte, T.J. de; Kroger, N.

    2013-01-01

    Outcomes and prognostic factors of reduced intensity-conditioned allo-SCT (RIC allo-SCT) for multiple myeloma (MM) relapsing or progressing after prior autologous (auto)-SCT are not well defined. We performed an analysis of 413 MM patients who received a related or unrelated RIC allo-SCT for the

  15. Autologous or reduced-intensity conditioning allogeneic hematopoietic cell transplantation for chemotherapy-sensitive mantle-cell lymphoma: analysis of transplantation timing and modality.

    Science.gov (United States)

    Fenske, Timothy S; Zhang, Mei-Jie; Carreras, Jeanette; Ayala, Ernesto; Burns, Linda J; Cashen, Amanda; Costa, Luciano J; Freytes, César O; Gale, Robert P; Hamadani, Mehdi; Holmberg, Leona A; Inwards, David J; Lazarus, Hillard M; Maziarz, Richard T; Munker, Reinhold; Perales, Miguel-Angel; Rizzieri, David A; Schouten, Harry C; Smith, Sonali M; Waller, Edmund K; Wirk, Baldeep M; Laport, Ginna G; Maloney, David G; Montoto, Silvia; Hari, Parameswaran N

    2014-02-01

    To examine the outcomes of patients with chemotherapy-sensitive mantle-cell lymphoma (MCL) following a first hematopoietic stem-cell transplantation (HCT), comparing outcomes with autologous (auto) versus reduced-intensity conditioning allogeneic (RIC allo) HCT and with transplantation applied at different times in the disease course. In all, 519 patients who received transplantations between 1996 and 2007 and were reported to the Center for International Blood and Marrow Transplant Research were analyzed. The early transplantation cohort was defined as those patients in first partial or complete remission with no more than two lines of chemotherapy. The late transplantation cohort was defined as all the remaining patients. Auto-HCT and RIC allo-HCT resulted in similar overall survival from transplantation for both the early (at 5 years: 61% auto-HCT v 62% RIC allo-HCT; P = .951) and late cohorts (at 5 years: 44% auto-HCT v 31% RIC allo-HCT; P = .202). In both early and late transplantation cohorts, progression/relapse was lower and nonrelapse mortality was higher in the allo-HCT group. Overall survival and progression-free survival were highest in patients who underwent auto-HCT in first complete response. Multivariate analysis of survival from diagnosis identified a survival benefit favoring early HCT for both auto-HCT and RIC allo-HCT. For patients with chemotherapy-sensitive MCL, the optimal timing for HCT is early in the disease course. Outcomes are particularly favorable for patients undergoing auto-HCT in first complete remission. For those unable to achieve complete remission after two lines of chemotherapy or those with relapsed disease, either auto-HCT or RIC allo-HCT may be effective, although the chance for long-term remission and survival is lower.

  16. Summary of round robin measurements of radiation induced conductivity in Wesgo AL995 alumina

    Energy Technology Data Exchange (ETDEWEB)

    Zinkle, S.J. [Oak Ridge National Lab., TN (United States)

    1996-10-01

    This existing data on radiation induced conductivity (RIC) measurements performed on the same heat of the IEA reference ceramic insulator are summarized. Six different sets of RIC measurements have been performed on Wesgo AL995 at dose rates between 10 Gy/s and 1 MGy/s. In general, good agreement was obtained between the different groups of researchers. The data indicate that the RIC at a test temperature of 400-500{degrees}C is approximately linear with ionizing dose rate up to {approximately}1000 Gy/s, and exhibits an approximately square root dependence on dose rate between 1 kGy/s and 1 MGy/s.

  17. DNA-PK inhibition causes a low level of H2AX phosphorylation and homologous recombination repair in Medaka (Oryzias latipes) cells

    International Nuclear Information System (INIS)

    Urushihara, Yusuke; Kobayashi, Junya; Matsumoto, Yoshihisa; Komatsu, Kenshi; Oda, Shoji; Mitani, Hiroshi

    2012-01-01

    Highlights: ► We investigated the effect of DNA-PK inhibition on DSB repair using fish cells. ► A radiation sensitive mutant RIC1 strain showed a low level of DNA-PK activity. ► DNA-PK dysfunction leads defects in HR repair and DNA-PKcs autophosphorylation. ► DNA-PK dysfunction leads a slight increase in the number of 53BP1 foci after DSBs. ► DNA-PK dysfunction leads an alternative NHEJ that depends on 53BP1. -- Abstract: Nonhomologous end joining (NHEJ) and homologous recombination (HR) are known as DNA double-strand break (DSB) repair pathways. It has been reported that DNA-PK, a member of PI3 kinase family, promotes NHEJ and aberrant DNA-PK causes NHEJ deficiency. However, in this study, we demonstrate that a wild-type cell line treated with DNA-PK inhibitor and a mutant cell line with dysfunctional DNA-PK showed decreased HR efficiency in fish cells (Medaka, Oryzias latipes). Previously, we reported that the radiation-sensitive mutant RIC1 strain has a defect in the Histone H2AX phosphorylation after γ-irradiation. Here, we showed that a DNA-PK inhibitor, NU7026, treatment resulted in significant reduction in the number of γH2AX foci after γ-irradiation in wild-type cells, but had no significant effect in RIC1 cells. In addition, RIC1 cells showed significantly lower levels of DNA-PK kinase activity compared with wild-type cells. We investigated NHEJ and HR efficiency after induction of DSBs. Wild-type cells treated with NU7026 and RIC1 cells showed decreased HR efficiency. These results indicated that aberrant DNA-PK causes the reduction in the number of γH2AX foci and HR efficiency in RIC1 cells. We performed phosphorylated DNA-PKcs (Thr2609) and 53BP1 focus assay after γ-irradiation. RIC1 cells showed significant reduction in the number of phosphorylated DNA-PKcs foci and no deference in the number of 53BP1 foci compared with wild-type cells. These results suggest that low level of DNA-PK activity causes aberrant DNA-PKcs autophosphorylation

  18. Reduced-intensity conditioning allogeneic SCT as salvage treatment for relapsed multiple myeloma.

    Science.gov (United States)

    de Lavallade, H; El-Cheikh, J; Faucher, C; Fürst, S; Stoppa, A-M; Coso, D; Bouabdallah, R; Chabannon, C; Gastaut, J-A; Blaise, D; Mohty, M

    2008-06-01

    The aim of this retrospective analysis was to assess the benefit of reduced-intensity conditioning allo SCT (RIC allo-SCT) in a cohort of 32 relapsed multiple myeloma (MM) patients. A total of 19 patients had an HLA-identical sibling donor ('donor' group), while 13 patients had no donor ('no-donor' group). There were no significant differences between these two groups as for prognosis risk factors. Eighteen patients from the 'donor' group could actually proceed to RIC allo-SCT. With a median follow-up of 36 (range, 21-60) months, six patients died from transplant-related toxicity (cumulative incidence, 33% (95% CI, 11-55%)). Only 4 patients from the 18 transplanted patients (22%; 95% CI, 7-48%) progressed after RIC allo-SCT, as compared to 12 (86%; 95% CI, 56-98%; P=0.0003) among the nontransplanted patients. In an 'intention-to-treat' analysis, the Kaplan-Meier estimate of PFS was significantly higher in the 'donor' group as compared to the 'no-donor' group (P=0.01; 46 versus 8% at 3 years). There was no difference in terms of overall survival. However, in multivariate analysis, actual performance of RIC allo-SCT was associated with better PFS (relative risk, 0.35; 95% CI, 0.15-0.82; P=0.01). These data suggest a potential benefit for RIC allo-SCT in the management of relapsed MM warranting further prospective investigations.

  19. 78 FR 40960 - Drawbridge Operation Regulation; Lake Washington Ship Canal at Seattle, WA

    Science.gov (United States)

    2013-07-09

    ..., WA. The deviation is necessary to accommodate the ``See Jane Run Women's Half Marathon.'' This... Manager, Docket Operations, telephone 202-366-9826. SUPPLEMENTARY INFORMATION: The SDOT requested a... necessary to accommodate the ``See Jane Run Women's Half Marathon''. This deviation allows the bridges to...

  20. Cancer increase study methodology: A review and discussion of the ''Southeastern Massachusetts Health Study 1978--1986''

    International Nuclear Information System (INIS)

    Sever, L.E.; Baker, D.A.; Gilbert, E.S.; Mahaffey, J.A.

    1993-09-01

    In October 1990 the Massachusetts Department of Public Health released a report of an epidemiologic study of adult leukemia occurring in the vicinity of the Pilgrim 1 Nuclear Power Plant near Plymouth, Massachusetts. The study used a case-control design in which adult leukemia cases occurring between 1978 and 1986 in 22 towns were compared with persons without leukemia (controls) selected from the same study population. Exposure scores, used to estimate potential for exposure to radioactive emissions from Pilgrim, were calculated for all cases and controls. When the exposure scores of cases were compared with those of controls, the analyses showed the scores to be higher for the leukemia cases, suggesting that individuals with the highest potential for exposure to Pilgrim emissions had a significantly increased risk of leukemia. This association was found only for cases diagnosed before 1984; for cases diagnosed during 1984, 1985, or 1986, no association was observed between leukemia case status and potential for exposure to emissions from the plant. Our review of the report and supporting documents shows no major methodologic problems that would account for the finding of an association between leukemia risk and the Pilgrim plant. Examination of the study findings in relation to what is known about leukemia risks associated with radiation exposure, however, indicates that the results of the Southeastern Massachusetts Health Study are inconsistent with a large body of evidence from a number of other studies

  1. Chaplain, soldier, counselor, pilgrim.

    Science.gov (United States)

    Muse, Stephen

    2004-01-01

    The author offers examples of supervision drawing on object relations therapy and Christian faith, doctrine, and life, designed to facilitate theological integration of pastoral identity and clinical practice in the training of U.S. Army Family Life Chaplains. Therapeutic and supervisory relationships are conceived of as dia-Logos encounters requiring the same degree of ascetical sobriety, presence, and vulnerability as prayer and worship. Concepts of therapeutic aggression, functional atheism, and "not knowing" are linked with on-going self-examination and repentance stimulated by empathic engagement of clients as primary ingredients for spiritual growth and effective pastoral counseling.

  2. The Ambiguity of Justice: Paul Ricoeur on Universalism and Evil

    Directory of Open Access Journals (Sweden)

    Geoffrey Dierckxsens

    2016-01-01

    Full Text Available In this article I will examine Ricœur’s idea of the universal in his understanding of justice. Scholars recently discussed the extent to which Ricœur understands universal moral norms and universal rules of justice in his anthropology of human action (e.g., J. Michel, Paul Ricœur: une philosophie de l’agir humain, Paris: Les Éditions du Cerf, 2006, and argue that Ricœur stresses too much the idea of universal moral norms with regard to cultural and moral diversity (e.g., G. H. Taylor, “Ricoeur versus Ricoeur? Between the Universal and the Contextual,” From Ricoeur to Action. The Socio-Political Significance of Ricoeur’s Thinking, Todd S. Mei and David Lewin (eds., (London and New York: Bloomsbury, 2012. G. H. Taylor, “Reenvisioning Justice,” Lo Squarda 12 (2013: 65-80. In this article I will take part in the debate about universalism and approach Ricœur’s idea of the universal from a different angle, in placing it in light of his idea of evil. The point I will aim to make in this article is that Ricœur’s idea of the relation between justice and evil demonstrates what I understand as the ambiguity of justice, which highlights the difficulty of defining universal rules of justice. I will argue that this ambiguity is the following: justice aims at the establishment of social peace and in that sense it is the necessary remedy against human evil, but justice also implies power, and possibly violence, over others in that it relates to violent feelings of vengeance, to institutional mechanism of authority, and to a struggle of values. Yet if rules of justice relate to evil in the sense of power over others, so I argue, then it is problematic to define absolute criteria for rules of justice, i.e., for rules for social peace: because justice relates to particular values, which means that the risk of violence is inherent to institutional rules of justice, there is no ultimate universal set of such rules. This article therefore

  3. Cleaning lady saves the day

    CERN Multimedia

    2009-01-01

    At lunch time on Wednesday 21 January a guest at the CERN hostel put her food in the microwave oven and switched it on. "Within seconds I smelt plastic. I looked into the oven and saw flames. I switched it off, took my food out. But the flames continued and so I ran for the door." In the corridor she ran into Jane Kiranga, a cleaning lady working for the company ISS. Without hesitation Jane picked up a portable fire extinguisher, returned to the kitchen and stopped the fire. The Fire Brigade arrived a few minutes later and only needed to ventilate the kitchen. "Jane was just in time, because the flames had not left the oven yet. Her model behaviour deserves recognition," said the team leader on duty for the CERN Fire Brigade. A few days later Jane received a gift voucher from the Prevention and Training section of the Safety Commission (photo).

  4. Gamma ray induced electrical conductivity in bisphenol-A type epoxy resin and polyethylene terephthalate

    International Nuclear Information System (INIS)

    Maeda, Hideaki; Nakakita, Tsuneo

    1978-01-01

    The insulation materials to support magnets for nuclear fusion reactors are exposed to high energy neutron beam and the gamma ray due to the accompanying induced radio activity through blankets or radiation shields. In such materials, radiation-induced conduction (RIC) is a problem, which occurs due to the charged particles generated in the insulation materials during irradiation. As one of such materials, use of epoxy composite material is expected, but its RIC has been scarcely measured. An approach to measure the wave form of transient current (or electric charge) caused by irradiating the radiation pulses of nano-second order to the materials has been developed. This paper reports the results of having measured RIC in bisphenol-A type epoxy resin at the electric field from 1 x 10 4 to 3 x 10 5 V/cm and γ dose rate from 9 x 10 3 to 9 x 10 5 R/h over the temperature range of -170 deg. C to +110 deg. C. The RIC of polyethylene terephthalate (PET) was also measured in the same regions, whose molecular structure is comparatively similar to the bisphenol-A type epoxy resin, and of which the fundamental processes for RIC have been clarified pretty well. The radiation sources of 4.3 kCi 60 Co of NAIG and 45 kCi 60 Co of JAERI were used. The experimental circuits and the cryostat are described, then as for the results, explanation and discussion are given to the characteristics of induced current, dependence on dose rate and dependence on temperature of RIC conductivity. The process of capturing carrier in deep traps seems to be dominant in the bisphenol-A type epoxy resin, similarly to that of PET. (Wakatsuki, Y.)

  5. Remote Ischemic Conditioning and Renal Protection.

    Science.gov (United States)

    Giannopoulos, Georgios; Vrachatis, Dimitrios A; Panagopoulou, Vasiliki; Vavuranakis, Manolis; Cleman, Michael W; Deftereos, Spyridon

    2017-07-01

    Over the course of the last 2 decades, the concept of remote ischemic conditioning (RIC) has attracted considerable research interest, because RIC, in most of its embodiments offers an inexpensive way of protecting tissues against ischemic damage inflicted by a number of medical conditions or procedures. Acute kidney injury (AKI) is a common side effect in the context of various medical procedures, and RIC has been suggested as a means of reducing its incidence. Outcomes regarding kidney function have been reported in numerous studies that evaluated the effects of RIC in a variety of settings (eg, cardiac surgery, interventions requiring intravenous administration of contrast media). Although several individual studies have implied a beneficial effect of RIC in preserving kidney function, 3 recently published randomized controlled trials evaluating more than 1000 patients each (Effect of Remote Ischemic Preconditioning in the Cardiac Surgery, Remote Ischaemic Preconditioning for Heart Surgery, and ERICCA) were negative. However, AKI or any other index of renal function was not a stand-alone primary end point in any of these trials. On the other hand, a range of meta-analyses (each including thousands of participants) have reported mixed results, with the most recent among them showing benefit from RIC, pinpointing at the same time a number of shortcomings in published studies, adversely affecting the quality of available data. The present review provides a critical appraisal of the current state of this field of research. It is the opinion of the authors of this review that there is a clear need for a common clinical trial framework for ischemic conditioning studies. If the current babel of definitions, procedures, outcomes, and goals persists, it is most likely that soon ischemic conditioning will be "yesterday's news" with no definitive conclusions having been reached in terms of its real clinical utility.

  6. 26 CFR 1.1296-1 - Mark to market election for marketable stock.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Mark to market election for marketable stock. 1....1296-1 Mark to market election for marketable stock. (a) Definitions—(1) Eligible RIC. An eligible RIC... included in gross income by the company pursuant to such mark to market election with respect to such stock...

  7. Russia and the BRICS:

    DEFF Research Database (Denmark)

    Skak, Mette

    Russia's role as driver behind the BRICS is critically examined via the original RIC concept of Primakov. Today, there are mixed feelings about the BRICS in Russia.......Russia's role as driver behind the BRICS is critically examined via the original RIC concept of Primakov. Today, there are mixed feelings about the BRICS in Russia....

  8. Argentina, de territoris a províncies: una mirada des de l'Estat, l'educació i la premsa (segles XIX i XX

    Directory of Open Access Journals (Sweden)

    Martha Ruffini

    2016-05-01

    Full Text Available El present dossier, divers pel que fa a les àrees geogràfiques i continguts, té com a objectiu mostrar un fil conductor comú, és a dir, descobrir processos històrics que van tenir lloc en espais considerats perifèrics o marginals dins el territori argentí.

  9. 0ric;inal. articles

    African Journals Online (AJOL)

    P ... dipstix urine is exaritined for glucose, protein and ketones; capillary blood ..... breadths) and function (grip strength of both hands and neuromuscular ... should take the form of improved diet, increased exercise, and plenty of time spent ...

  10. The Convergence of Ricoeur’s and Von Wright’s Complex Models of History

    Directory of Open Access Journals (Sweden)

    Linda L. Cox

    2014-07-01

    Full Text Available The relationship between the structural identity of narrative and the truth claim of the historical narrative work is one of importance to Ricœur. He considers the attempts of two interwoven models of history emerging from analytic philosophy—explanatory and narrative—to articulate this relationship. This paper explores the trajectories of these models as well as the epistemological and ontological crises culminating from the “simple” theses of each model. The solution to these crises requires a more complex method to account for the nature of the connections underlying historical understanding. Georg Henrik von Wright’s provisional or “hybrid” model of explanation and understanding revises the simple explanatory model and is foundational for Ricœur’s own complex revision of narrativist models through his notion of questioning back. The present paper argues that the structure of this hybrid model was unsatisfactory for von Wright, and leads in the direction of Ricœur’s own narrative method. Keywords: Ricœur, von Wright, Narrative, History, Questioning back. Résumé La relation entre l’identité structurale du récit et la prétention à la vérité de l’œuvre de récit historique est fondamentale chez Ricœur. Il considère que les deux modèles historiographiques de provenance analytique – le modèle explicatif et le modèle narratif – peuvent s’articuler. Cet article explore les trajectoires de ces modèles autant que les crises épistémologiques et ontologiques qui culminent dans chacune des thèses prise dans un sens unilatéral. La solution pour remédier à ces crises requiert une méthode plus complexe pour tenir compte de la nature des liens qui sous-tendent la compréhension historique. Le modèle d’explication et de compréhension, provisoire et “hybride,” de Georg Henrik von Wright permet de réviser le simple modèle explicatif. Ceci est fondamental pour comprendre  la révision complexe que

  11. Detection and characterization of flaws in segments of light water reactor pressure vessels

    International Nuclear Information System (INIS)

    Cook, K.V.; Cunningham, R.A. Jr.; McClung, R.W.

    1988-01-01

    Studies have been conducted to determine flaw density in segments cut from light water reactor )LWR) pressure vessels as part of the Oak Ridge National Laboratory's Heavy-Section Steel Technology (H SST) Program. Segments from the Hope Creek Unit 2 vessel and the Pilgrim Unit 2 Vessel were purchased from salvage dealers. Hope Creek was a boiling water reactor (BWR) design and Pilgrim was a pressurized water reactor (PWR) design. Neither were ever placed in service. Objectives were to evaluate these LWR segments for flaws with ultrasonic and liquid penetrant techniques. Both objectives were successfully completed. One significant indication was detected in a Hope Creek seam weld by ultrasonic techniques and characterized by further analyses terminating with destructive correlation. This indication [with a through-wall dimension of ∼6 mm (∼0.24 in.)] was detected in only 3 m (10 ft) of weldment and offers extremely limited data when compared to the extent of welding even in a single pressure vessel. However, the detection and confirmation of the flaw in the arbitrarily selected sections implies the Marshall report estimates (and others) are nonconservative for such small flaws. No significant indications were detected in the Pilgrim material by ultrasonic techniques. Unfortunately, the Pilgrim segments contained relatively little weldment; thus, we limited our ultrasonic examinations to the cladding and subcladding regions. Fluorescent liquid penetrant inspection of the cladding surfaces for both LWR segments detected no significant indications [i.e., for a total of approximately 6.8 m 2 (72 ft 2 ) of cladding surface]. (author)

  12. Dinamika haji Indonesia sejak era kolonial dan problematika calon haji ilegal

    Directory of Open Access Journals (Sweden)

    Moh. Rosyid

    2017-12-01

    Full Text Available The number of Indonesian pilgrims every year is increasing. On the other hand, the allocation of the number of pilgrims to be dispatched is limited by the quota. This triggers the waiting list and the share of various hajj efforts despite the violation of the law. However, not pilgrims know that pilgrimage using other country’s passport is a violation of Law No. 12 of 2006 on Citizenship and possible losing of one's nationality. From historical perspective, Muslims’ pilgrim dated back from the 16th century. At that time, there was strong suspicion that upon returning from pilgrimage, Muslims tend to be “rebellious” and initiated movement against the Dutch colonial government. Thus, the Dutch made a strict regulation concerning the Hajj and scrutinized Muslims before pilgrimage, while staying in Mecca and after their return. Among the movement against the Dutch led by Muslim upon returning the Hajj was the Padri movement. Nowadays, the number of Muslims who intend to go Hajj is rising significantly, and the waiting list goes for 15 to 20 years. The long list caused some people to find a way to go for Hajj including manipulation of citizenship documents, such as using passport of other countries. In respond to this situation, the government tries to negotiate with the Saudi government to increase the Hajj quota for Indonesians. Another effort is borrowing the remaining quota of neighboring countries. There is also suggestion to close the Hajj registration for some time and the need to revise the Hajj Law.

  13. "It's Almost like a White School Now": Racialised Complexities, Indigenous Representation and School Leadership

    Science.gov (United States)

    Keddie, Amanda; Niesche, Richard

    2012-01-01

    Drawing on a broader study that focused on examining principal leadership for equity and diversity, this paper presents the leadership experiences of "Jane", a White, middle-class principal of a rural Indigenous school. The paper highlights how Jane's leadership is inextricably shaped by her assumptions about race and the political dynamics and…

  14. Making Socialists: Mary Bridges Adams and the Fight for Knowledge and Power, 1855-1939

    Science.gov (United States)

    Weiler, Kathleen

    2012-01-01

    This article presents a review of "Making socialists: Mary Bridges Adams and the fight for knowledge and power, 1855-1939," by Jane Martin. Jane Martin has explored the history of late-nineteenth-century and early-twentieth century-British women educational activists in numerous publications over the past two decades. Her first book,…

  15. Some functional inequalities on non-reversible Finsler manifolds

    Indian Academy of Sciences (India)

    SHIN-ICHI OHTA

    2017-11-13

    Nov 13, 2017 ... In the reversible case, these inequalities were obtained by. Cavalletti and ... active area. The classical Riemannian theory has been generalized to weighted Rieman- .... Define the dual Minkowski norm F. ∗: T. ∗ .... We also define Ric∞(v) and Ricn(v) as the limits and set RicN (cv) := c2RicN (v) for c ≥ 0.

  16. Walking the Spiritual Ways – West of Ireland experience of modern pilgrimage

    Directory of Open Access Journals (Sweden)

    Rosemary Power

    2015-07-01

    Full Text Available This paper considers the modern phenomenon of pilgrim walking along routes in the west of Ireland county of Clare. It relates it to possible medieval practice; to traditional practices by local people on one hand and the reconstruction of the international medieval pilgrim routes to places like Compostela. It suggests the reasons why people may walk in search of spiritual growth and experience, the resources they may wish for, the ways in which the contemporary search functions in a largely post-Catholic manner, and the position of those from other Christina, or religious traditions

  17. Small RNA-based feedforward loop with AND-gate logic regulates extrachromosomal DNA transfer in Salmonella.

    Science.gov (United States)

    Papenfort, Kai; Espinosa, Elena; Casadesús, Josep; Vogel, Jörg

    2015-08-25

    Horizontal gene transfer via plasmid conjugation is a major driving force in microbial evolution but constitutes a complex process that requires synchronization with the physiological state of the host bacteria. Although several host transcription factors are known to regulate plasmid-borne transfer genes, RNA-based regulatory circuits for host-plasmid communication remain unknown. We describe a posttranscriptional mechanism whereby the Hfq-dependent small RNA, RprA, inhibits transfer of pSLT, the virulence plasmid of Salmonella enterica. RprA employs two separate seed-pairing domains to activate the mRNAs of both the sigma-factor σ(S) and the RicI protein, a previously uncharacterized membrane protein here shown to inhibit conjugation. Transcription of ricI requires σ(S) and, together, RprA and σ(S) orchestrate a coherent feedforward loop with AND-gate logic to tightly control the activation of RicI synthesis. RicI interacts with the conjugation apparatus protein TraV and limits plasmid transfer under membrane-damaging conditions. To our knowledge, this study reports the first small RNA-controlled feedforward loop relying on posttranscriptional activation of two independent targets and an unexpected role of the conserved RprA small RNA in controlling extrachromosomal DNA transfer.

  18. Reusable Rack Interface Controller Common Software for Various Science Research Racks on the International Space Station

    Science.gov (United States)

    Lu, George C.

    2003-01-01

    The purpose of the EXPRESS (Expedite the PRocessing of Experiments to Space Station) rack project is to provide a set of predefined interfaces for scientific payloads which allow rapid integration into a payload rack on International Space Station (ISS). VxWorks' was selected as the operating system for the rack and payload resource controller, primarily based on the proliferation of VME (Versa Module Eurocard) products. These products provide needed flexibility for future hardware upgrades to meet everchanging science research rack configuration requirements. On the International Space Station, there are multiple science research rack configurations, including: 1) Human Research Facility (HRF); 2) EXPRESS ARIS (Active Rack Isolation System); 3) WORF (Window Observational Research Facility); and 4) HHR (Habitat Holding Rack). The RIC (Rack Interface Controller) connects payloads to the ISS bus architecture for data transfer between the payload and ground control. The RIC is a general purpose embedded computer which supports multiple communication protocols, including fiber optic communication buses, Ethernet buses, EIA-422, Mil-Std-1553 buses, SMPTE (Society Motion Picture Television Engineers)-170M video, and audio interfaces to payloads and the ISS. As a cost saving and software reliability strategy, the Boeing Payload Software Organization developed reusable common software where appropriate. These reusable modules included a set of low-level driver software interfaces to 1553B. RS232, RS422, Ethernet buses, HRDL (High Rate Data Link), video switch functionality, telemetry processing, and executive software hosted on the FUC computer. These drivers formed the basis for software development of the HRF, EXPRESS, EXPRESS ARIS, WORF, and HHR RIC executable modules. The reusable RIC common software has provided extensive benefits, including: 1) Significant reduction in development flow time; 2) Minimal rework and maintenance; 3) Improved reliability; and 4) Overall

  19. High treatment efficacy by dual targeting of Burkitt's lymphoma xenografted mice with a {sup 177}Lu-based CD22-specific radioimmunoconjugate and rituximab

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Tobias; Boetticher, Benedikt; Keller, Armin; Schlegelmilch, Anne; Jaeger, Dirk; Krauss, Juergen [Heidelberg University Hospital, Department of Medical Oncology, National Center for Tumor Diseases, Heidelberg (Germany); Mier, Walter; Kraemer, Susanne; Leotta, Karin [Heidelberg University Hospital, Department of Nuclear Medicine, Heidelberg (Germany); Sauter, Max; Haberkorn, Uwe [Heidelberg University Hospital, Department of Nuclear Medicine, Heidelberg (Germany); German Cancer Research Center (DKFZ), Clinical Cooperation Unit Nuclear Medicine, Heidelberg (Germany); Grosse-Hovest, Ludger [University of Tuebingen, Department of Immunology, Tuebingen (Germany); Arndt, Michaela A.E. [Heidelberg University Hospital, Department of Medical Oncology, National Center for Tumor Diseases, Heidelberg (Germany); German Cancer Research Center (DKFZ), Immunotherapy Program, National Center for Tumor Diseases, Heidelberg (Germany)

    2016-03-15

    Dual-targeted therapy has been shown to be a promising treatment option in recurrent and/or refractory B-cell non-Hodgkin's lymphoma (B-NHL). We generated radioimmunoconjugates (RICs) comprising either a novel humanized anti-CD22 monoclonal antibody, huRFB4, or rituximab, and the low-energy β-emitter {sup 177}Lu. Both RICs were evaluated as single agents in a human Burkitt's lymphoma xenograft mouse model. To increase the therapeutic efficacy of the anti-CD22 RIC, combination therapy with unlabelled anti-CD20 rituximab was explored. The binding activity of CHX-A''-DTPA-conjugated antibodies to target cells was analysed by flow cytometry. To assess tumour targeting of {sup 177}Lu-labelled antibodies, in vivo biodistribution experiments were performed. For radioimmunotherapy (RIT) studies, non-obese diabetic recombination activating gene-1 (NOD-Rag1{sup null}) interleukin-2 receptor common gamma chain (IL2r γ {sup null}) null mice (NRG mice) were xenografted subcutaneously with Raji Burkitt's lymphoma cells. {sup 177}Lu-conjugated antibodies were administered at a single dose of 9.5 MBq per mouse. For dual-targeted therapy, rituximab was injected at weekly intervals (0.5 - 1.0 mg). Tumour accumulation of RICs was monitored by planar scintigraphy. Conjugation of CHX-A''-DTPA resulted in highly stable RICs with excellent antigen-binding properties. Biodistribution experiments revealed higher tumour uptake of the {sup 177}Lu-labelled anti-CD22 IgG than of {sup 177}Lu-labelled rituximab. Treatment with {sup 177}Lu-conjugated huRFB4 resulted in increased tumour growth inhibition and significantly longer survival than treatment with {sup 177}Lu-conjugated rituximab. The therapeutic efficacy of the anti-CD22 RIC could be markedly enhanced by combination with unlabelled rituximab. These findings suggest that dual targeting with {sup 177}Lu-based CD22-specific RIT in combination with rituximab is a promising new treatment option for

  20. Hubungan Shalat Fardu Berjamaah Dengan Kecerdasan Emosional Pada Jamaah Mesjid Al Jihad Banjarmasin

    Directory of Open Access Journals (Sweden)

    Ahmad Jauhari

    2017-05-01

    Full Text Available Al Jihad  Mosque Banjarmasin is a mosque that is identical with Muhammadiyah, this mosque is followed by many pilgrims and loyal at the time of the implementation of prayers fardu congregation. Jamaah consists of various groups regardless of background, both in terms of age, economy, organization and even the sick pilgrims (post-stroke are actively involved in congregation. Active Jamaat prayers in congregation do not only come from residents around the mosque complex, but also many pilgrims who come from outside the mosque complex, even the distance difference between their residence with the mosque a few kilometers. In heavy rainy weather conditions, they still enthusiastically follow the prayers in congregation fardu mosque. In addition, there are things that are felt by pilgrims such as comfort, tranquility of heart and mind, emotional stability, silaturrahim which all is related to emotional intelligence. In this study, the main problem is how is the relationship of prayer in congregation with emotional intelligence in the congregation of Al Jihad Mosque Banjarmasin ?. The method used is quantitative and qualitative descriptive method with methodological arrangement such as approach and type of research, research location, population and sample, data and data source, procedure and data collection, quantitative and qualitative technical data analysis. The result of the study found that there is a correlation between salat fardu congregation with emotional intelligence, this is proved by the data from questionnaires from 30 pilgrims (respondents that is: able to control the impulse of worldly lusts with the highest opinion is 60% said yes and 40% stated sometimes .Motivating yourself with the highest opinion is 90% states yes and 10% states sometimes. Able to survive in the face of trials with the highest opinion is 86.67 states yes and 13, 33 states sometimes. No exaggeration with the highest opinion is 90% states yes and 10% states

  1. KARIER MENINGITIS MENINGOKOK PADA JEMAAH HAJI INDONESIA TAHUN 1993-2003

    Directory of Open Access Journals (Sweden)

    Sarwo Handayani

    2012-10-01

    Full Text Available Research and routine survey of meningococcal meningitis on Indonesian hajj pilgrims have been conducted since 1993 until now. This paper consists of several research and routine survey of meningococcal meningitis during 1993 and 2003. The objectives of the test were determining the meningococcal meningitis carrier on hajj pilgrims, determining the serogroup of N. meningitidis and knowing sensitivity of bacteria to several antibiotics. The result showed increasing of meningococcal meningitis carrier in 1993 up to 1996, that was 1.3% - 9,4% respectively. This proportion of meningococcal meningitis carrier in the case groups decreased after given of rifampicin in 1994 and cyprofloxacin in 1997 as a chemoprophilactic. The result of the study in 1997 indiciated that the carrier rate of groups with cyprofloxacin (1.4% was lower than rifampicin group (1.4%. Most of the isolated bacteria of N. meningitidis in 1996 and 1997 were resistant to rifampicin (sensitivity test was 0-33%. Serogroup B of N. meningitidis were found dominantly between 1993 and 1999, it changed to be serogroup W135 from 2000 to 2003. The changes related  with the majority cases of meningococcal meningitis in another countries that caused by serogroup W135. Because  of  that  since 2002, immunization program has given a tetravalen (serogroup ACYW135 meningococcal vaccine to all of Indonesian hajj pilgrims. The carrier of meningococcal meningitis is still found in hajj pilgrims and their contact. More attention must be given, caused of meningococcal meningitis serogroup B vaccine is not available. The further researches are needed especially for subtype of N. meningitidis, effectivity of the drug choice and development of meningococcal meningitis vaccine serogroup B.

  2. PELAKSANAAN PEMBIAYAAN DANA TALANGAN HAJI PADA PERBANKAN SYARIAH

    Directory of Open Access Journals (Sweden)

    Erni Susana

    2017-03-01

    Full Text Available The syariah banking activity was basically the expansion of banking service for people who needed it andexpected the repayment which was not based on interest rate, but based on syariah as what determined inIslamic law. To help people to get pilgrim portion soon, syahriah banking offered agreement which was usedin financing pilgrim lending fund like al-qardh agreement and al-ijarah (ujroh system. The aim of thisresearch was to analyze financing using al-qardh agreement and al-ijarah (ujroh system agreement. Al-qardhwas giving wealth to other people that could be collected back or asked for, or in other words lending withoutexpecting repayment, while the meaning of al-ijarah agreement was an agreement of moving the use or utilizationright on goods and service, through rent payment or ujroh without being followed by transferringownership. The implementation of financing pilgrim lending fund conformed to the rule of financing pilgrimarrangement which was written in Fatwa (a binding ruling in religious matters DSN No. 29/DSN-MUI/VI/2002. The amount of al-ijarah repayment was not based on the amount of lending al-qardh given to thecustomers.

  3. Home and Away: A Schoolmistress in Lowland Scotland and Colonial Australia in the Second Half of the Nineteenth Century

    Science.gov (United States)

    McDermid, Jane

    2011-01-01

    In this paper, the author discusses the life of Jane Hay Brown, later Hamilton (1827-1898), who worked as a governess and schoolmistress from the late 1840s to the mid 1880s. She was a woman whose life would have remained largely unknown without emigration which resulted in a rich collection of family letters. Jane's letters provide insight into…

  4. Respiratory tract infection during Hajj

    Directory of Open Access Journals (Sweden)

    Alzeer Abdulaziz

    2009-01-01

    Full Text Available Respiratory tract infection during Hajj (pilgrimage to Mecca is a common illness, and it is responsible for most of the hospital admissions. Influenza virus is the leading cause of upper respiratory tract infection during Hajj, and pneumonia can be serious. Taking into account the close contacts among the pilgrims, as well as the crowding, the potential for transmission of M. tuberculosis is expected to be high. These pilgrims can be a source for spreading infection on their return home. Although vaccination program for influenza is implemented, its efficacy is uncertain in this religious season. Future studies should concentrate on prevention and mitigation of these infections.

  5. Quelles pratiques sémiotiques pour quelles médiations ?

    Directory of Open Access Journals (Sweden)

    Anne Hénault

    2017-06-01

    ABSTRACT: In January 1963, Paul Ricœur was very interested in structuralism to which he had already devoted important readings (Rome, Entretiens Castelli. In June 1963, during a heated debate with C. Levi-Strauss, under the Esprit Journal, Ricœur developed a violent rejection of structural thought, and his resentment will endure until his last work, devoted to History, in 2002. Initially (up to 1979, this anathema was also aimed at A. J. Greimas and his semiotics. Then, following a series of university meetings and public debates with Greimas, Ricœur came to a complete change of view of Greimas's works, to the point of intimacy, at the last public debate between them (In 1989, not to use the pretext of his research on the semiotics of the passions to distance himself from his first semiotics (that which from the Sémantique structurale to the Dictionnaire comes to be known as "standard semiotics". After this, Ricœur explicitly formulated the idea that standard semiotics had elaborated a new rationality, the explanatory power of which was authentically "theoretical" and therefore scientific, which led him to admit that the semiotic explanation could be revealed necessary even in the field of Hermeneutics, in order to reach a more exact level of understanding.

  6. Determination of Dynamics of Plant Plasma Membrane Proteins with Fluorescence Recovery and Raster Image Correlation Spectroscopy.

    Science.gov (United States)

    Laňková, Martina; Humpolíčková, Jana; Vosolsobě, Stanislav; Cit, Zdeněk; Lacek, Jozef; Čovan, Martin; Čovanová, Milada; Hof, Martin; Petrášek, Jan

    2016-04-01

    A number of fluorescence microscopy techniques are described to study dynamics of fluorescently labeled proteins, lipids, nucleic acids, and whole organelles. However, for studies of plant plasma membrane (PM) proteins, the number of these techniques is still limited because of the high complexity of processes that determine the dynamics of PM proteins and the existence of cell wall. Here, we report on the usage of raster image correlation spectroscopy (RICS) for studies of integral PM proteins in suspension-cultured tobacco cells and show its potential in comparison with the more widely used fluorescence recovery after photobleaching method. For RICS, a set of microscopy images is obtained by single-photon confocal laser scanning microscopy (CLSM). Fluorescence fluctuations are subsequently correlated between individual pixels and the information on protein mobility are extracted using a model that considers processes generating the fluctuations such as diffusion and chemical binding reactions. As we show here using an example of two integral PM transporters of the plant hormone auxin, RICS uncovered their distinct short-distance lateral mobility within the PM that is dependent on cytoskeleton and sterol composition of the PM. RICS, which is routinely accessible on modern CLSM instruments, thus represents a valuable approach for studies of dynamics of PM proteins in plants.

  7. Limb Remote Ischemic Conditioning: Mechanisms, Anesthetics, and the Potential for Expanding Therapeutic Options

    Science.gov (United States)

    Chen, Gangling; Thakkar, Mrugesh; Robinson, Christopher; Doré, Sylvain

    2018-01-01

    Novel and innovative approaches are essential in developing new treatments and improving clinical outcomes in patients with ischemic stroke. Remote ischemic conditioning (RIC) is a series of mechanical interruptions in blood flow of a distal organ, following end organ reperfusion, shown to significantly reduce infarct size through inhibition of oxidation and inflammation. Ischemia/reperfusion (I/R) is what ultimately leads to the irreversible brain damage and clinical picture seen in stroke patients. There have been several reports and reviews about the potential of RIC in acute ischemic stroke; however, the focus here is a comprehensive look at the differences in the three types of RIC (remote pre-, per-, and postconditioning). There are some limited uses of preconditioning in acute ischemic stroke due to the unpredictability of the ischemic event; however, it does provide the identification of biomarkers for clinical studies. Remote limb per- and postconditioning offer a more promising treatment during patient care as they can be harnessed during or after the initial ischemic insult. Though further research is needed, it is imperative to discuss the importance of preclinical data in understanding the methods and mechanisms involved in RIC. This understanding will facilitate translation to a clinically feasible paradigm for use in the hospital setting. PMID:29467715

  8. Social Movements in Post-Revolutionary Iran

    Science.gov (United States)

    2013-12-01

    Oppositional Consciousness,” in the Oppositional Consciousness: The Subjective Roots of Social Protest, ed. Jane Mansbridge and Aldon Morris (Chicago...Taheri’s funeral on Tuesday , June 4.183 Although the effects of the Green Movement on the 2013 Iranian presidential elections were not clear and...In the Oppositional Consciousness: The Subjective Roots of Social Protest, edited by Jane Mansbridge and Aldon Morris . Chicago: University of

  9. Analysis of the Capabilities Supporting Humanitarian Assistance and Disaster Relief Operations of the Indonesian Navy (TNI AL) and the United States Marine Corps Marine Expeditionary Unit (USMC MEU)

    Science.gov (United States)

    2015-12-01

    Operating Procedure SPMAGTF Special Purpose Marine Air Ground Task Force SSB Single Side Band STP Shock Trauma Platoon TACRON Tactical Air Control...Platoon ( STP ) that is capable of conducting emergency treatment and triage. The remaining corpsmen are dispersed throughout the individual sub-units of...Jane’s navigating the emerging markets , Indonesia. Retrieved from Jane’s Information Group https://janes.ihs.com.libproxy.nps.edu/CustomPages/Janes

  10. Automated refueling inventory control system at FFTF

    International Nuclear Information System (INIS)

    Ordonez, C.R.

    1983-10-01

    The Refueling Inventory Control System (RICS) at the Fast Flux Test Facility (FFTF) keeps track of all assemblies that reside in the various refueling facilities. The automated RICS allows the user to obtain information regarding any assembly under its control by displaying the data on a screen. It also provides a simulation mode which allows assembly moves on a duplicated data base. This simulation is used to verify the refueling documentation before it is issued

  11. Événement, idéologie et utopie

    Directory of Open Access Journals (Sweden)

    Jean-Luc AMALRIC

    2014-12-01

    Full Text Available RESUMEL’hypothèse que tente d’esquisser cet article est que l’idée ricœurienne d’une médiatisation dynamique des contradictions de l’imaginaire social présuppose une corrélation originaire de l’idéologie et de l’utopie qui ne peut elle-même être comprise qu’à partir de l’événement de l’institution d’un imaginaire social constituant. Dans un premier temps, l’article s’efforce de cerner ce qui fait la spécificité de la théorie ricœurienne de l’idéologie et de l’utopie comme « pratiques imaginatives », en soulignant à ce titre l’influence déterminante des thèses de Jacques Ellul sur l’idéologie. Puis, dans un second temps, il s’engage dans une analyse régressive qui conduit de la réappropriation ricœurienne de la conception dialectique de l’idéologie et de l’utopie exposée par Mannheim à l’idée d’un fondement événementiel de ces deux formes opposées de l’imaginaire social.Mots-Clés : Evénement, idéologie, utopie, Ellul, Mannheim. ABSTRACTThis paper attempts to sketch out the hypothesis that the Ricœurian conception of a dynamic mediatization of the contradictions of the social imaginary presupposes an original correlation between ideology and utopia, which can itself be understood only from the event that institutes a constitutive social imaginary. The first part of the paper marks out the specificity of the Ricœurian theory of ideology and utopia in terms of “imaginative practices”, underlining the determining influence of Jacques Ellul’s theses on ideology. The second part tries to develop a regressive argument, starting from the Ricœurian re-appropriation of Mannheim’s dialectical conception of ideology and utopia, and leading back to the idea of an event foundation for these two opposed forms of the social imaginary.Keywords : Event, Ideology, Utopia, Ellul, Mannheim   

  12. High Concentrations of Measles Neutralizing Antibodies and High-Avidity Measles IgG Accurately Identify Measles Reinfection Cases

    Science.gov (United States)

    Rota, Jennifer S.; Hickman, Carole J.; Mercader, Sara; Redd, Susan; McNall, Rebecca J.; Williams, Nobia; McGrew, Marcia; Walls, M. Laura; Rota, Paul A.; Bellini, William J.

    2016-01-01

    In the United States, approximately 9% of the measles cases reported from 2012 to 2014 occurred in vaccinated individuals. Laboratory confirmation of measles in vaccinated individuals is challenging since IgM assays can give inconclusive results. Although a positive reverse transcription (RT)-PCR assay result from an appropriately timed specimen can provide confirmation, negative results may not rule out a highly suspicious case. Detection of high-avidity measles IgG in serum samples provides laboratory evidence of a past immunologic response to measles from natural infection or immunization. High concentrations of measles neutralizing antibody have been observed by plaque reduction neutralization (PRN) assays among confirmed measles cases with high-avidity IgG, referred to here as reinfection cases (RICs). In this study, we evaluated the utility of measuring levels of measles neutralizing antibody to distinguish RICs from noncases by receiver operating characteristic curve analysis. Single and paired serum samples with high-avidity measles IgG from suspected measles cases submitted to the CDC for routine surveillance were used for the analysis. The RICs were confirmed by a 4-fold rise in PRN titer or by RT-quantitative PCR (RT-qPCR) assay, while the noncases were negative by both assays. Discrimination accuracy was high with serum samples collected ≥3 days after rash onset (area under the curve, 0.953; 95% confidence interval [CI], 0.854 to 0.993). Measles neutralizing antibody concentrations of ≥40,000 mIU/ml identified RICs with 90% sensitivity (95% CI, 74 to 98%) and 100% specificity (95% CI, 82 to 100%). Therefore, when serological or RT-qPCR results are unavailable or inconclusive, suspected measles cases with high-avidity measles IgG can be confirmed as RICs by measles neutralizing antibody concentrations of ≥40,000 mIU/ml. PMID:27335386

  13. Jane Addams’ Social Vision

    DEFF Research Database (Denmark)

    Villadsen, Kaspar

    2018-01-01

    resonated with key tenets of social gospel theology, which imbued her texts with an overarching vision of humanity’s progressive history. It is suggested that Addams’ vision of a major transition in industrial society, one involving a BChristian renaissance^ and individuals’ transformation into Bsocialized...

  14. Jane's School Safety Handbook.

    Science.gov (United States)

    Wong, Marleen; Kelly, James; Stephens, Ronald D.

    This book advises schools in a concise, detailed format about crisis management. Its chapters address: (1) crisis planning; (2) early warning signs; (3) crisis response; (4) crisis recovery; (5) case studies of schools that have encountered crisis situations; and (6) sample letters to be distributed in case of crisis. (Appendices discuss…

  15. Katrin Pajuste / Jane Frey

    Index Scriptorium Estoniae

    Frey, Jane, 1950-

    2005-01-01

    24. septembril 2004. a. kaitses Katrin Pajuste Tartu Ülikoolis väitekirja teemal "Õhusaasteainete sadenemine ja transformeerumine okaspuumetsades: Eesti riiklike seireandmete põhjal" ("Deposition and transformation of air pollutants in coniferous forests: a study based on Estonian monitoring data")

  16. Cosmological Analysis of Dynamical Chern-Simons Modified Gravity via Dark Energy Scenario

    Directory of Open Access Journals (Sweden)

    Abdul Jawad

    2015-01-01

    Full Text Available The purpose of this paper is to study the cosmological evolution of the universe in the framework of dynamical Chern-Simons modified gravity. We take pilgrim dark energy model with Hubble and event horizons in interacting scenario with cold dark matter. For this scenario, we discuss cosmological parameters such as Hubble and equation of state and cosmological plane like ωϑ-ωϑ′ and squared speed of sound. It is found that Hubble parameter approaches the ranges 75-0.5+0.5 (for u=2 and (74, 74.30 (for u=1,-1,-2 for Hubble horizon pilgrim dark energy. It implies the ranges 74.80-0.005+0.005 (for u=2 and (73.4, 74 (for u=-2 for event horizon pilgrim dark energy. The equation of state parameter provides consistent ranges with different observational schemes. Also, ωϑ-ωϑ′ planes lie in the range (ωϑ=-1.13-0.25+0.24,ωϑ′<1.32. The squared speed of sound shows stability for all present models in the present scenario. We would like to mention here that our results of various cosmological parameters show consistency with different observational data like Planck, WP, BAO, H0, SNLS, and WMAP.

  17. Les ruines à l'épreuve de La mémoire, l'histoire, l'oubli: Imaginer se souvenir?

    Directory of Open Access Journals (Sweden)

    Laure Barillas

    2017-07-01

    Full Text Available What place should be given to ruins in the phenomenology of memory sketched by Ricœur in Memory, History, Forgetting? The contemplation of ruins raises the same problem as that which occupies the whole of Ricœur’s work: the representation of the past and the relations of memory and imagination in the formation of recollection. Can ruins give rise to a rearrangement of the relations of memory and imagination and produce an “imagining remembering”?

  18. 78 FR 29131 - Environmental Impacts Statements; Notice of Availability

    Science.gov (United States)

    2013-05-17

    ..., Clinker Mining Addition Project, Medicine Bow-Routt National Forests and Thunder Basin National Grassland..., USFS, MT, Pilgrim Timber Sale Project, Kootenai National Forest, Review Period Ends: 06/17/2013...

  19. EVOLUTION DU CONCEPT DE LA QUALITE DE VIE AU MAROC : CAS DE LA POLYARTHRITE RHUMATOÏDE ET DE LA SPONDYLOARTHRITE ANKYLOSANTE

    Directory of Open Access Journals (Sweden)

    Hanan RKAIN

    2017-05-01

    Full Text Available La polyarthrite rhumatoïde et la spondylarthrite ankylosante sont à la tête des rhumatismes inflammatoires chroniques (RIC. La souffrance engendrée par la douleur chronique rhumatismale, le retentissement sur le vécu journalier des patients et leur entourage, altèrent incontestablement la qualité de vie des patients. Ce travail reprend de manière succincte les études ayant abordé cet aspect chez les patients marocains souffrant de PR et de SPA. Ces travaux font l’unanimité sur la perturbation de la qualité de vie des patients marocains souffrant de ces RIC en affectant considérablement les domaines physique, psychique et social. Les études longitudinales, réalisées en particulier dans la PR, attestent de l’intérêt de la prise en charge adéquate de ces RIC pour améliorer la qualité de vie du patient marocain.

  20. Should elderly patients with higher-risk myelodysplastic syndromes undergo allogeneic hematopoietic stem cell transplantation?

    Science.gov (United States)

    Zeidan, Amer M; Gore, Steven D

    2013-10-01

    Myelodysplastic syndromes (MDS) include a group of hematopoietic malignancies characterized by dysplastic changes, ineffective hematopoiesis and variable risk of leukemic progression. At diagnosis, 86% of MDS patients are ≥60 years. Azacitidine, the only drug that prolongs life in high-risk (HR)-MDS patients, adds a median of only 9.5 months to life. Allogeneic stem cell transplantation (alloSCT) remains the only potentially curative approach. Despite recent improvements including use of reduced intensity conditioning (RIC) that decrease transplant-related mortality, alloSCT continues to be used rarely in elderly MDS. There is paucity of data regarding outcomes of RIC alloSCT in elderly MDS patients, especially in direct comparison with azanucleosides. In this paper, the authors discuss the recent Markov decision analysis by Koreth et al. in which investigators demonstrated superior survival of patients with HR-MDS aged 60-70 years who underwent RIC alloSCT in comparison with those who were treated with azanucleosides.

  1. Psychiatric Symptoms and Barriers to Care in HIV-Infected Individuals Who Are Lost to Care.

    Science.gov (United States)

    McLean, Carmen P; Gay, Natalie G; Metzger, David A; Foa, Edna B

    Past studies of barriers to HIV care have not comprehensively assessed psychiatric symptoms, and few have assessed barriers to care among people living with HIV (PLWH) who are lost to care (LTC). We examined psychiatric symptoms, barriers to HIV care, and immune functioning in PLWH who were retained in care (RIC; n = 21) or LTC (n = 21). Participants completed diagnostic interviews for posttraumatic stress disorder (PTSD) and other psychiatric disorders, self-report measures of HIV risk behaviors and psychiatric symptoms, and a blood draw to assess viral load. Compared to RIC participants, LTC participants met criteria for a greater number of psychiatric disorders and reported greater depressive symptoms and more barriers to HIV care. There were no group differences in PTSD severity, risk behaviors, or viral load, suggesting that LTC individuals experience greater psychiatric problems and perceive more barriers to care than RIC participants, but are not less likely to have achieved viral suppression.

  2. mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3

    DEFF Research Database (Denmark)

    Kleinert, Maximilian; Parker, Benjamin L; Chaudhuri, Rima

    2016-01-01

    culture. RESULTS: Ric mKO mice exhibited a greater reliance on fat as an energy substrate, a re-partitioning of lean to fat mass and an increase in intramyocellular triglyceride (IMTG) content, along with increases in several lipid metabolites in muscle. Unbiased proteomics revealed an increase......OBJECTIVE: We have recently shown that acute inhibition of both mTOR complexes (mTORC1 and mTORC2) increases whole-body lipid utilization, while mTORC1 inhibition had no effect. Therefore, we tested the hypothesis that mTORC2 regulates lipid metabolism in skeletal muscle. METHODS: Body composition...... in the expression of the lipid droplet binding protein Perilipin 3 (PLIN3) in muscle from Ric mKO mice. This was associated with increased AMPK activity in Ric mKO muscle. Reducing AMPK kinase activity decreased muscle PLIN3 expression and IMTG content. AMPK agonism, in turn, increased PLIN3 expression in a FoxO1...

  3. Remote Ischemic Conditioning

    Science.gov (United States)

    Heusch, Gerd; Bøtker, Hans Erik; Przyklenk, Karin; Redington, Andrew; Yellon, Derek

    2014-01-01

    In remote ischemic conditioning (RIC) brief, reversible episodes of ischemia with reperfusion in one vascular bed, tissue or organ confer a global protective phenotype and render remote tissues and organs resistant to ischemia/reperfusion injury. The peripheral stimulus can be chemical, mechanical or electrical and involves activation of peripheral sensory nerves. The signal transfer to the heart or other organs is through neuronal and humoral communications. Protection can be transferred, even across species, with plasma-derived dialysate and involves nitric oxide, stromal derived factor-1α, microRNA-144, but also other, not yet identified factors. Intracardiac signal transduction involves: adenosine, bradykinin, cytokines, and chemokines, which activate specific receptors; intracellular kinases; and mitochondrial function. RIC by repeated brief inflation/deflation of a blood pressure cuff protects against endothelial dysfunction and myocardial injury in percutaneous coronary interventions, coronary artery bypass grafting and reperfused acute myocardial infarction. RIC is safe and effective, noninvasive, easily feasible and inexpensive. PMID:25593060

  4. The Later Wittgenstein and the Later Husserl on Language

    Directory of Open Access Journals (Sweden)

    Paul Ricoeur

    2014-07-01

    Full Text Available This article presents an edited version of lectures given by Paul Ricœur at Johns Hopkins University in April 1966. Ricœur offers a comparative analysis of Wittgenstein’s and Husserl’s late works, taking the problem of language as the common ground of investigation for these two central figures of phenomenology and analytic philosophy. Ricœur develops his study in two parts. The first part considers Husserl’s approach to language after the Logical Investigations and concentrates on Formal and Transcendental Logic; leaving a transcendental reflection on language behind it re-examines a phenomenological conception, according to which the sphere of logic is not separable from that of experience. The main focus of the second part is Wittgenstein’s later philosophy as it moved on from the conception of an isomorphic relation between language and the world, as set out in the picture theory in the Tractatus Logico-Philosophicus, to the more pragmatic notion of a language-game in the Philosophical Investigations. In order to get beyond the irrevocable differences between the two philosophies and the unresolved theoretical issues on both sides, Ricœur suggests turning to a semiological paradigm based on the Saussurean distinction between “language” and “speaking.” Keywords: Analytic Philosophy, Husserl, Phenomenology, Semiology, Wittgenstein.Résumé Cet article est une version éditée de conférences données par Paul Ricœur à la Johns Hopkins University en avril 1966. Ricœur propose une analyse comparée des dernières œuvres de Wittgenstein et Husserl, avec le problème du langage comme sol commun d’investigations pour ces deux figures centrales de la phénoménologie et la philosophie analytique. Cette analyse de Ricœur se joue à travers deux parties. La première partie revient sur l'approche du langage chez Husserl depuis Recherches logiques avec une attention particulière aux développements de Logique formelle et

  5. Les ruminantia (Artiodactyla, Mammalia du miocene des bugti (Balouchistan, Pakistan

    Directory of Open Access Journals (Sweden)

    Soria, D.

    2001-08-01

    Full Text Available The revision of the old material studied by Pilgrim (1908, 191 1, 1912, Forster Cooper, 1915 added to the study of the fossils recently yielded in the synclinal of Dera Bugti (Southem Pakistan by Welcome and its team (Welcomme et al., 1997 leads to consider the existence of five ruminats genera (Siarnotragulus, Dorcahune, Progiraffa, Bugtimeryx, Eotragus, belonging to eigth species.La revisión de los materiales descritos por Pilgrim (1908, 1911, 1912, Forster Cooper, 1915 junto al estudio de los hallazgos recientes realizados en el sinclinal de Dera Bugti (Sur de Paquistán por Welcomme et al. (1997, nos permite reconocer en esta área cinco géneros de ruminantes (Siamotragulus, Dorcahune, Progiraffa, Bugtimeryx, Eotragus con un total de ocho especies.

  6. An expert system for diesel generator diagnostics

    International Nuclear Information System (INIS)

    Bley, D.C.; Read, J.W.; Kaplan, S.; Liming, J.K.; Brosee, N.M.; Hanley, D.W.

    1987-01-01

    The idea of developing artificial intelligence (AI) systems to capture the knowledge of human experts is receiving much attention these days. The idea is even more attractive when important expertise resides within a single individual, especially one who is nearing retirement and who has not otherwise recorded or passed along his important knowledge and thought processes. The diesel generators at Pilgrim Nuclear Power Station have performed exceptionally well, primarily due to the care and attention of one man. Therefore, the authors are constructing an expert system for the diagnosis of diesel generator problems at Pilgrim. This paper includes a description of the expert system design and operation, examples from the knowledge base, and sample diagnoses, so the reader can observe the process in action

  7. Book Reviews

    OpenAIRE

    Redactie KITLV

    2001-01-01

    -Virginia R. Dominguez, Louis A. Pérez, Jr., On becoming Cuban: Identity, nationality, and culture. Chapel Hill: University of North Carolina Press, 1999. xiv + 579 pp. -Solimar Otero, Kali Argyriadis, La religión à la Havane: Actualités des représentations et des pratiques culturelles havanaises. Paris: Éditions des Archives Contemporaines,1999. 373 pp. -Jane Desmond, Jane Blocker, Where is Ana Mendieta?: Identity, performativity, and exile. Durham NC: Duke University Press, 1999. xvi + 166 ...

  8. Built to Last: The Army’s Failed Quest to Replace the Bradley Fighting Vehicle

    Science.gov (United States)

    2015-05-23

    NAME OF RESPONSIBLE PERSON Harley P. Jennings a. REPORT b. ABSTRACT c. THIS PAGE 19b. PHONE NUMBER (include area code ) (U) (U) (U) Unlimited 44...the MICV Task Force to conduct an independent study of the MICV program. System requirements changed because of the task force’s findings. Led by...37 Christopher F. Foss, ed., Jane’s Armour and Artillery 2011-2012, 32 ed. (New York: Janes Information Group, 2011), 443. 38 Haworth, The

  9. [Paulo Coelho. Zahir ; Jan Kaus. Tema] / Aarne Biin

    Index Scriptorium Estoniae

    Biin, Aarne

    2007-01-01

    Tutvustus: Coelho, Paulo. Zahir : [romaan] / portugali keelest tõlkinud Anneli Tuulik, [Konstantinos Kavafise luuletuse uuskreeka keelest tõlkinud Mati Sirkel. Tallinn] : Pilgrim Group, 2005 ; Kaus, Jan. Tema : [romaan]. Tallinn : Tuum, 2006

  10. Task constraints distinguish perspective inferences from perspective use during discourse interpretation in a false belief task.

    Science.gov (United States)

    Ferguson, Heather J; Apperly, Ian; Ahmad, Jumana; Bindemann, Markus; Cane, James

    2015-06-01

    Interpreting other peoples' actions relies on an understanding of their current mental states (e.g. beliefs, desires and intentions). In this paper, we distinguish between listeners' ability to infer others' perspectives and their explicit use of this knowledge to predict subsequent actions. In a visual-world study, two groups of participants (passive observers vs. active participants) watched short videos, depicting transfer events, where one character ('Jane') either held a true or false belief about an object's location. We tracked participants' eye-movements around the final visual scene, time-locked to related auditory descriptions (e.g. "Jane will look for the chocolates in the container on the left".). Results showed that active participants had already inferred the character's belief in the 1s preview period prior to auditory onset, before it was possible to use this information to predict an outcome. Moreover, they used this inference to correctly anticipate reference to the object's initial location on false belief trials at the earliest possible point (i.e. from "Jane" onwards). In contrast, passive observers only showed evidence of a belief inference from the onset of "Jane", and did not show reliable use of this inference to predict Jane's behaviour on false belief trials until much later, when the location ("left/right") was auditorily available. These results show that active engagement in a task activates earlier inferences about others' perspectives, and drives immediate use of this information to anticipate others' actions, compared to passive observers, who are susceptible to influences from egocentric or reality biases. Finally, we review evidence that using other peoples' perspectives to predict their behaviour is more cognitively effortful than simply using one's own. Copyright © 2015 Elsevier B.V. All rights reserved.

  11. Development of a surgical site infection (SSI) surveillance system, calculation of SSI rates and specification of important factors affecting SSI in a digestive organ surgical department.

    Science.gov (United States)

    Kimura, Koji; Sawa, Akihiro; Akagi, Shinji; Kihira, Kenji

    2007-06-01

    We have developed an original system to conduct surgical site infection (SSI) surveillance. This system accumulates SSI surveillance information based on the National Nosocomial Infections Surveillance (NNIS) System and the Japanese Nosocomial Infections Surveillance (JNIS) System. The features of this system are as follows: easy input of data, high generality, data accuracy, SSI rate by operative procedure and risk index category (RIC) can be promptly calculated and compared with the current NNIS SSI rate, and the SSI rates and accumulated data can be exported electronically. Using this system, we monitored 798 patients in 24 operative procedure categories in the Digestive Organs Surgery Department of Mazda Hospital, Mazda Motor Corporation, from January 2004 through December 2005. The total number and rate of SSI were 47 and 5.89%, respectively. The SSI rates of 777 patients were calculated based on 15 operative procedure categories and Risk Index Categories (RIC). The highest SSI rate was observed in the rectum surgery of RIC 1 (30%), followed by the colon surgery of RIC3 (28.57%). About 30% of the isolated infecting bacteria were Enterococcus faecalis, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Escherichia coli. Using quantification theory type 2, the American Society of Anesthesiology score (4.531), volume of hemorrhage under operation (3.075), wound classification (1.76), operation time (1.352), and history of diabetes (0.989) increased to higher ranks as factors for SSI. Therefore, we evaluated this system as a useful tool in safety control for operative procedures.

  12. Tidal and residual currents across the northern Ryukyu Island chain observed by ferryboat ADCP

    Science.gov (United States)

    Liu, Zhao-Jun; Nakamura, Hirohiko; Zhu, Xiao-Hua; Nishina, Ayako; Dong, Menghong

    2017-09-01

    Ferryboat Acoustic Doppler Current Profiler (ADCP) data from 2003 to 2012 are used to estimate the tidal and residual currents across the northern Ryukyu Island chain (RIC) between the islands of Okinawa and Amamioshima. In this region, the M2 tide current is the strongest tidal component, and the K1 tide current is the strongest diurnal tidal component. The corresponding maximum amplitudes are 40 and 34 cm s-1, respectively. After removal of the tidal currents, the mean volume transport, 1.5 ± 2.7 Sv, flows into the East China Sea (ECS) from the western North Pacific through four channels in this area. In an empirical orthogonal function (EOF) analysis performed to clarify the temporal and spatial variability of currents through the four channels, the first two EOF modes account for 71% and 18% of the total variance, respectively. The EOF1 mode shows a clear bottom-intensified mode through the deep channel, which is likely to be formed by the propagation of bottom-trapped long topographic Rossby wave caused by the impingement of westward-propagating mesoscale eddies upon the eastern slope of the northern RIC. The EOF2 mode has significant seasonal variability and may be driven by the wind stress prevailing over the Kuroshio flow region around the northern RIC in October-November. This study provides observational evidence of the water exchanges across the northern RIC, which is essential for constructing a circulation scheme in the North Pacific subtropical western boundary region.

  13. 77 FR 16098 - In the Matter of All Operating Boiling Water Reactor Licensees With Mark I and Mark II...

    Science.gov (United States)

    2012-03-19

    .... Jack M. Davis Senior Vice President and Chief Nuclear Officer. Detroit Edison Company Fermi 2--210 NOC..., Inc Pilgrim Nuclear Power Station 600 Rocky Hill Road Plymouth, MA 02360-5508 Quad Cities Nuclear...

  14. Japan and the Soviet Threat: Perceptions and Reactions.

    Science.gov (United States)

    1983-12-01

    missile sights (HAWK and NIKE ) are aging and capabilities against high speed aircraft are questionable. Some of these missiles will be replaced with...trans. DSJP, Nov. 10, T, p. 10). CHAPTER VI 1. Kiyokai Murata, "Yoshida vs . Dulles," The Japan Times Weekly, Oct. 9e 1982, p. 4. 2. Mike M. Mochizuki...DSJP, June 23, 1983, p. 4). 12. Christopher F. Foss, ed., Jane’s Armour and Artillery: 1982-83 (London: Jane’s Publishing Co., Ltd., 1982) and JDA

  15. A vision of transdisciplinarity laying foundations for a world knowledge dialogue

    CERN Document Server

    Darbellay, Frederic; Billotte, Jerome; Waldvogel, Francis

    2008-01-01

    AcknowledgementsWhere, and Whence ?by André HurstThe Rules of the Game for a Knowledge Dialoguexby Dame Julia HigginsIntroductionFor a World Knowledge Dialogueby Frédéric Darbellay, Moira Cockell, Jérôme Billotte andFrancis WaldvogelChapter 1 Complexity and Neurosciences in Dialogue :Towards a New Theory of the Brain ?1.1 From Brain Dynamics to Consciousness :How Matter Becomes ImaginationAnalysis by Frédéric Darbellay of the presentationby Gerald M. Edelman1.2 Towards a Neuroscience of the Capable Perso

  16. Molecular and Genomic Characterization of Enteric Pathogens Circulating during Hajj

    KAUST Repository

    Alsomali, Mona

    2016-05-01

    Hajj, the annual Muslim pilgrimage to Mecca, Saudi Arabia is a unique mass gathering event that attracts approximately 3 million pilgrims from around the globe. This diverse pilgrim population coupled with the nature of the performed activities raise major public health concerns in the host country with potential global implications. Although gastroenteritis and diarrhea are common among the pilgrims performing Hajj, the microbial etiologies of these infections are still unknown. We used molecular and antigenic approaches to identify the main pathogens associated with Hajj diarrhea. 544 fecal samples from pilgrims suffering from diarrhea whilst performing Hajj during three consecutive seasons (2011-2013) and 99 control samples from 2011 were screened for 16 pathogens that include bacterial, parasitic and viral etiologies that are commonly associated with diarrheal infections. At least one of the screened pathogens could be detected in 42% (n=228) of the samples from the diarrheal cases. Bacteria were the main agents detected in 83% (n=189) of the positive samples, followed by viral and parasitic agents detected in 6% (n=14) and 5% (n=12) respectively. We have also standardized a 16S-based metagenomic approach to identify the gut microbiome in diarrheal cases and non-diarrheal controls in 76 samples. Also, we have standardized a shotgun metagenomics protocol for the direct characterization (diagnosis) of enteric pathogens without cultivation. This approach was used successfully to identify viral (adenovirus) and bacterial causes of Enterotoxigenic E. coli diarrhea from Hajj samples. The findings in this study fill in clear gaps in our knowledge of the etiologies associated with diarrheal infections during Hajj. Foodborne bacteria were the major contributors to Hajj-diarrheal infections. This was coupled with the increased incidences of antimicrobial resistance loci associated with the identified bacteria. These findings would help the public health policy makers to

  17. 77 FR 1950 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Science.gov (United States)

    2012-01-12

    ..., Wind Turbine Blade Division. 80,512 Pilgrim's Pride Dallas, TX Corporation. I hereby certify that the........... February 13, 2010. Inc. 81,009 Birds Eye Foods, LLC, Fulton, NY February 13, 2010. Fulton, NY Plant...

  18. Kuu filmid / toimetanud Maria Ulfsak-Šeripova

    Index Scriptorium Estoniae

    2010-01-01

    Eesti Filmiajakirjanike Ühingu ajakirjanike koostatud filmiprogrammist kinos Artis, Uue Saksa kino festivalist 6.-12. okt. ja režissöör Edgar Wright'i filmist "Scott Pilgrim terve maailma vastu" (USA 2010)

  19. Awe: An Important Emotional Experience in Sustainable Tourism

    Directory of Open Access Journals (Sweden)

    Dong Lu

    2017-11-01

    Full Text Available “Awesome” is one of the most highly desirable experiences for tourists. This study investigates how tourists’ awe emotion is induced when tourists visit sacred mountains and how the awe experience influences their satisfaction. A survey is administrated at a famous sacred mountain in China—Mount Emei. Results reveal that the awe experience is more elicited by the perceived vastness of natural environment for secular tourists, while is more encouraged by the perceived sanctity of religious ambience for pilgrim tourists. Awe experience is a mediator between the sense of perceptual vastness/sanctity and tourists’ satisfaction. The mediation relationships through awe experience are moderated by the visitor types (pilgrims and secular tourists. Findings suggest that destination marketers should apply tourism strategies to encourage tourists’ sense of awe.

  20. 76 FR 72077 - Thanksgiving Day, 2011

    Science.gov (United States)

    2011-11-21

    ... generously extending their knowledge of local game and agriculture to the Pilgrims, and today we renew our... us offer gratitude to our men and women in uniform for their many sacrifices, and keep in our...

  1. The Paediatric Cardiology Hall of Fame – Donald Nixon Ross.

    Science.gov (United States)

    Somerville, Jane

    2015-10-01

    Donald Nixon Ross, FRCS (4 October 1922 to 7 July 2014) was a South African-born British cardiothoracic surgeon, who developed the pulmonary autograft, known as the Ross procedure, for the treatment of aortic valve disease, and also performed the first heart transplant in the United Kingdom in 1968. This paper, written by Jane Somerville, Professor of Cardiology [Retired], Imperial College London, London, United Kingdom, provides the personal recollections about Donald Ross from Jane Somerville, and thus provides a unique snapshot of cardiac surgical history.

  2. Remote ischemic conditioning: A treatment for vascular cognitive impairment

    Directory of Open Access Journals (Sweden)

    David C Hess

    2015-01-01

    Full Text Available There is a strong link between hypoperfusion and white matter (WM damage in patients with leukoaraiosis and vascular cognitive impairment (VCI. Other than management of vascular risk factors, there is no treatment for WM damage and VCI that delays progression of the disease process to dementia. Observational studies suggest that exercise may prevent or slow down the progression of Alzheimer′s disease (AD and VCI. However, getting patients to exercise is challenging, especially with advancing age and disability. Remote ischemic conditioning, an "exercise equivalent," allows exercise to be given with a "device" at home for long periods of time. Since remote ischemic conditioning (RIC increases cerebral blood flow (CBF in preclinical studies and in humans, RIC may be an ideal therapy to treat VCI and WM disease and perhaps even sporadic AD. By using magnetic resonance imaging (MRI imaging of WM progression, a sample size in the range of about 100 subjects per group could determine if RIC has activity in WM disease and VCI.

  3. Radiation-induced electrical conductivity in MgAl2O4 spinel

    International Nuclear Information System (INIS)

    Pells, G.P.

    1990-12-01

    The d.c. electrical conductivity of high purity, polycrystalline MgAl 2 O 4 spinel of 99.5% theoretical density has been measured during irradiation by 18 MeV protons at reactor relevant ionization dose rates. The radiation-induced conductivity (RIC) at 200 C varied in a slightly sub-linear manner with dose rate. At temperatures between 250-350 C the RIC varied in a complex manner with the dose rate dependence being itself dose rate dependent. At higher temperatures the RIC reverted to an essentially linear variation with dose rate. The complex dose rate dependence is ascribed to the magnesium vacancy concentration introduced by the small Al 2 O 3 excess (MgO:Al 2 O = 1:1.05) and the presence of anti-structure defects producing large concentrations of intrinsic electron and hole traps. There was no evidence that the accumulation of radiation damage influenced the details of radiation-induced conductivity and MgAl 2 O 4 retained reasonable insulating properties at the highest dose rate and temperature. (author)

  4. Tumor sterilization dose and radiation induced change of the brain tissue in radiotherapy of brain tumors

    International Nuclear Information System (INIS)

    Yoshii, Yoshihiko; Maki, Yutaka; Takano, Shingo

    1987-01-01

    Ninety-seven patients with brain tumors (38 gliomas, 26 brain metastases, 18 sellar tumors, 15 others) were treated by cobalt gamma ray or proton radiotherapy. In this study, normal brain injury due to radiation was analysed in terms of time-dose-fractionation (TDF), nominal standard dose (NSD) by the Ellis formula and NeuNSD by a modification in which the N exponent was -0.44 and the T exponent was -0.06. Their calculated doses were analysed in relationship to the normal brain radiation induced change (RIC) and the tumor sterilization dose. All brain tumors with an exception of many patients with brain metastases were received a surgical extirpation subtotally or partially prior to radiotherapy. And all patients with glioma and brain metastasis received also immuno-chemotherapy in the usual manner during radiotherapy. The calculated dose expressed by NeuNSD and TDF showed a significant relationship between a therapeutic dose and a postradiation time in terms of the appearance of RIC. It was suggested that RIC was caused by a dose over 800 in NeuNSD and a dose over 70 in TDF. Furthermore, it was suggested that an aged patient and a patient who had the vulnerable brain tissue to radiation exposure in the irradiated field had the high risk of RIC. On the other hand, our results suggested that the tumor sterilization dose should be over 1,536 NeuNSD and the irradiated method should be further considered in addition to the radiobiological concepts for various brain tumors. (author)

  5. Radiation- and photoinduced processes in glass-like arsenic trisulfide and triselenide

    International Nuclear Information System (INIS)

    Matkovskij, A.O.; Shvarts, K.K.; Pirogov, F.V.; Shpotyuk, O.I.; Savitskij, I.V.

    1988-01-01

    Peculiarities of photo-structural transformations and results of gamma- and electron-radiation effect upon microhardness, optical absorption, IK and EPR spectra have been studied for glassy chalcogenide semiconductors (GCS). It has been shown that high-energy-radiation-induced changes in the GCS physical properties depend on radiation parameters, thermal conditions and the composition of the sample. Mechanisms of radiation-induced transformations (RIC) for glassy arsenic trisulfide and triselenide are discussed. The RIC is supposed to have been predetermined by the following correlated processes: destruction-polymerization, radiation defect formation, and impurity radiolysis. 77 refs.; 10 figs.; 2 tabs

  6. OntoWEDSS - An Ontology-based Environmental Decision-Support System for the management of Wastewater treatment plants

    OpenAIRE

    Ceccaroni, Luigi

    2001-01-01

    Les contribucions d'aquesta tesi uneixen dues disciplines: ciències ambientals (específicament, gestió d'aigües residuals) i informàtica (específicament, intel·ligència artificial). El tractament d'aigües residuals com a disciplina opera fent servir un rang de diferents enfocaments i mètodes que inclouen: control manual, control automàtic on-line, modelat numèric o no-numèric, models estadístics i simulacions. La tesi caracteritza la recerca interdisciplinària de tècniques d'intel·ligència ar...

  7. Surface shear stress dependence of gas transfer velocity parameterizations using DNS

    Science.gov (United States)

    Fredriksson, S. T.; Arneborg, L.; Nilsson, H.; Handler, R. A.

    2016-10-01

    Air-water gas-exchange is studied in direct numerical simulations (DNS) of free-surface flows driven by natural convection and weak winds. The wind is modeled as a constant surface-shear-stress and the gas-transfer is modeled via a passive scalar. The simulations are characterized via a Richardson number Ri=Bν/u*4 where B, ν, and u* are the buoyancy flux, kinematic viscosity, and friction velocity respectively. The simulations comprise 0Ric or kg=AShearu*Sc-n, Ri<Ric. Here ABuoy=0.4 and AShear=0.1 are constants, and n is an exponent that depends on the water surface-characteristics.

  8. Tuberculosis and mass gatherings-opportunities for defining burden, transmission risk, and the optimal surveillance, prevention, and control measures at the annual Hajj pilgrimage.

    Science.gov (United States)

    Zumla, Alimuddin; Saeed, Abdulaziz Bin; Alotaibi, Badriah; Yezli, Saber; Dar, Osman; Bieh, Kingsley; Bates, Matthew; Tayeb, Tamara; Mwaba, Peter; Shafi, Shuja; McCloskey, Brian; Petersen, Eskild; Azhar, Esam I

    2016-06-01

    Tuberculosis (TB) is now the most common infectious cause of death worldwide. In 2014, an estimated 9.6 million people developed active TB. There were an estimated three million people with active TB including 360000 with multidrug-resistant TB (MDR-TB) who were not diagnosed, and such people continue to fuel TB transmission in the community. Accurate data on the actual burden of TB and the transmission risk associated with mass gatherings are scarce and unreliable due to the small numbers studied and methodological issues. Every year, an estimated 10 million pilgrims from 184 countries travel to the Kingdom of Saudi Arabia (KSA) to perform the Hajj and Umrah pilgrimages. A large majority of pilgrims come from high TB burden and MDR-TB endemic areas and thus many may have undiagnosed active TB, sub-clinical TB, and latent TB infection. The Hajj pilgrimage provides unique opportunities for the KSA and the 184 countries from which pilgrims originate, to conduct high quality priority research studies on TB under the remit of the Global Centre for Mass Gatherings Medicine. Research opportunities are discussed, including those related to the definition of the TB burden, transmission risk, and the optimal surveillance, prevention, and control measures at the annual Hajj pilgrimage. The associated data are required to develop international recommendations and guidelines for TB management and control at mass gathering events. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  9. Effect of integrated pest management on controlling zoonotic cutaneous leishmaniasis in Emamzadeh Agha Ali Abbas (AS) District, Isfahan province, 2006-2009.

    Science.gov (United States)

    Nilforoushzadeh, Mohammad Ali; Shirani-Bidabadi, Leila; Saberi, Sedigheh; Hosseini, Seyed Mohsen; Jaffary, Fariba

    2014-01-01

    Cutaneous leishmaniasis (CL) is still considered as a health problem in the world. Several methods of control in different regions, together with obtaining integrated information on its natural foci, are needed to decrease its prevalence. This study was designed to evaluate the effects of simultaneous interventions on CL control. A standard questionnaire was used to identify patients among pilgrims to Emamzadeh Agha Ali Abbas (Isfahan Province, Iran). Subsequently, three methods of controlling the disease, including, spraying residential buildings with Baygon, baiting with zinc phosphide poisons, changing the vegetative cover of the region, improving the environment, and mounting a mesh on all doors and windows of buildings in residential areas were used. The control measures were then evaluated by comparing the number of pilgrims affected by CL after and before the interventions. While 23 pilgrims (1.4%) were affected with CL before the intervention (pretest), five (0.3%) persons were found to have CL after taking control measures. The Chi-square test did not indicate any significant difference in the relative frequency of CL (P = 0.731). The only scientific method for preventing and controlling zoonotic CL (ZCL) is a combination of the control methods (improving the environment and fighting off the disease districts and vectors) together with changing the vegetative cover of the region. Any measure for controlling this disease must be taken and programmed in accordance with the relevant experts' views, in coordination with the participation of other organizations and the society.

  10. Bayesian network model of crowd emotion and negative behavior

    Science.gov (United States)

    Ramli, Nurulhuda; Ghani, Noraida Abdul; Hatta, Zulkarnain Ahmad; Hashim, Intan Hashimah Mohd; Sulong, Jasni; Mahudin, Nor Diana Mohd; Rahman, Shukran Abd; Saad, Zarina Mat

    2014-12-01

    The effects of overcrowding have become a major concern for event organizers. One aspect of this concern has been the idea that overcrowding can enhance the occurrence of serious incidents during events. As one of the largest Muslim religious gathering attended by pilgrims from all over the world, Hajj has become extremely overcrowded with many incidents being reported. The purpose of this study is to analyze the nature of human emotion and negative behavior resulting from overcrowding during Hajj events from data gathered in Malaysian Hajj Experience Survey in 2013. The sample comprised of 147 Malaysian pilgrims (70 males and 77 females). Utilizing a probabilistic model called Bayesian network, this paper models the dependence structure between different emotions and negative behaviors of pilgrims in the crowd. The model included the following variables of emotion: negative, negative comfortable, positive, positive comfortable and positive spiritual and variables of negative behaviors; aggressive and hazardous acts. The study demonstrated that emotions of negative, negative comfortable, positive spiritual and positive emotion have a direct influence on aggressive behavior whereas emotion of negative comfortable, positive spiritual and positive have a direct influence on hazardous acts behavior. The sensitivity analysis showed that a low level of negative and negative comfortable emotions leads to a lower level of aggressive and hazardous behavior. Findings of the study can be further improved to identify the exact cause and risk factors of crowd-related incidents in preventing crowd disasters during the mass gathering events.

  11. Ziarah Perspektif Kajian Budaya (Studi Pada Situs Makam Mbah Priuk Jakarta Utara

    Directory of Open Access Journals (Sweden)

    Syahdan Syahdan

    2017-06-01

    Full Text Available Pilgrimage in this study tries to investigate from the perspective of cultural study, they are form (significant, function (application, interaction and meaning (signifie. This study aimed to obtain information about the process of pilgrimage ritual at the tomb of Mbah Priuk, also trying to comprehend the function and meaning contained in the pilgrimage ritual activities conducted at the tomb of Mbah Priuk. The results obtained in this study show that all the informants who researcher encountered have similar view about Mbah Priuk. The people’s motive who do pilgrimage, in general, is to pray and make Mbah Priuk as a mediator. The unique ritual done by pilgrims is throwing banknotes or coins into a small pond. In this ritual many pilgrims choose the pool eventhough there is already a place to put the money provided by the cemetary organizer. 

  12. Consensus recommendation for meningococcal disease prevention for Hajj and Umra pilgrimage/travel medicine.

    Science.gov (United States)

    Shibl, A; Tufenkeji, H; Khalil, M; Memish, Z

    2013-04-01

    The Islamic Hajj to Makkah (Mecca) has been associated with outbreaks of invasive meningococcal disease and the global spread of Neisseria meningitidis serogroup W-135. For Hajj pilgrims the quadrivalent vaccination against serogroups A, C, W-135 and Y is a mandatory requirement. Novel conjugate vaccines may provide benefits for the community by reduction of carriage. With the introduction of the new generation of quadrivalent meningococcal conjugate vaccines (Menveo, Menactra, and others pending license) and their recent implementation in Saudi Arabia, experts from 11 countries in the Middle East region met at a Meningococcal Leadership Forum (MLF), in Dubai in May 2010 to exchange opinions on meningococcal disease and prevention strategies. These experts discussed the importance of introducing conjugate vaccines for pilgrims and travellers, and elaborated a consensus recommendation to support healthcare professionals and decision-makers.

  13. Haiglate tegevuse hindamine / Jane Alop

    Index Scriptorium Estoniae

    Alop, Jane

    2005-01-01

    Maailma Terviseorganisatsiooni Euroopa piirkonna büroo poolt välja töötatud haiglate tegevuse hindamise metoodikast PATH (Performance Assessment Tool for quality improvement in Hospitals) ning selle rakendamisest Eestis. Joonis: PATH kontseptuaalne mudel

  14. Reading the Austen Project

    Directory of Open Access Journals (Sweden)

    Penny Gay

    2017-12-01

    Full Text Available The Austen Project: Jane Austen Re-imagined pairs six bestselling contemporary authors with Jane Austen’s six complete works. I propose to use this interesting (though obviously commercially based project to return to the intriguing critical issue of Jane Austen’s voice. How do the individual authors, all with established styles and audiences, deal with these demands? Whose voice does the reader hear in the narrative commentary? What is the difference, affectively, between the style and tone of the original novel and that of a contemporary writer who is not writing a pastiche but re-telling the story in modern terms? Equivalences in plot and characters are easy enough to do, and the re-imaginings so far published provide the modern reader with some delighted and/or surprised recognitions. But Austen’s famous irony, her rendition of the heroine’s thoughts from inside but also ‘beside’ the character’s viewpoint, her oblique critiques of her society and its manners – can they be re-imagined and re-rendered successfully?

  15. Translating Charlottes. Clare Boylan’s “The Secret Diary of Mrs Rochester”: Between Red Rooms and Yellow Wallpapers

    Directory of Open Access Journals (Sweden)

    Giovanna Tallone

    2014-01-01

    Full Text Available In her short story “The Secret Diary of Mrs Rochester”, Clare Boylan playfully uses a variation of the postmodern trend of “writing back” Victorian classics to create a sequel of Charlotte Brontë’s Jane Eyre (1847. Shedding light on Jane’s married life, Boylan makes a parody of Brontë’s language and narrative conventions making Jane an eccentric. In particular, the presence of closed spaces in the story replicates the claustrophobia of the red room in Jane Eyre, and from this point of view Boylan’s story bears parallelisms with Charlotte Perkins Gilman’s short story “The Yellow Wallpaper” (1892. Intertextuality and metanarrative perspectives of both stories draw attention to the textual space of the story and the elusive text that is being written/read. The “secret diary” assumed in the title is not the text that appears on the page. In both stories the protagonist and first-person narrator is engaged in writing an elusive text while confined in a secluded space. 

  16. Screening and evaluation of Second Half 1980 licensee event reports

    International Nuclear Information System (INIS)

    Waage, J.M.

    1981-09-01

    During the second part of 1980, two individual plant events occurred: Indian Point-2 (containment flooding) and Pilgrim-1 (uncontrolled blowdown). Significant event reports and update on generic problem areas and major equipment problem areas are included in this report

  17. The Pride and the Passion: Introduction to Black History.

    Science.gov (United States)

    Berry, Goodman

    1983-01-01

    The first Blacks in the Americas arrived before the Pilgrims landed at Plymouth Rock. Blacks have contributed to the development of the United States in the fields of government, education, science, music, entertainment (comedy and drama), literature, art, and athletics. (AOS)

  18. Caracterización epidemiológica y factores de riesgo asociados a la peregrinación religiosa a Arabia Saudí: Resultados de una cohorte prospectiva 2008-2009 Epidemiology and risk factors associated with religious pilgrimage to Saudi Arabia: Results of a prospective cohort 2008-2009

    Directory of Open Access Journals (Sweden)

    Lluís Valerio

    2012-06-01

    conducted of a cohort of pilgrims attended for pre-travel preventive activities in the North Metropolitan International Health Unit (Santa Coloma de Gramenet, Barcelona, Spain from 2009-2010. Results: A total of 193 pilgrims were assessed and 135 (69.9% were men. Their mean age (SD was 37.1 (16.9 years. Among the pilgrims, 176 (91.2% were immigrants, mainly from Pakistan (54.9%, Morocco (29%, Bangladesh (4.1% or other countries (7.2%. The pilgrims stayed in Saudi Arabia a mean (SD of 16.3 (9.2 days. Eighty (41.5% opted for the 1 month-long pilgrimage (Hajj and 113 (58.5% for the shorter Umra. One or more pathological antecedent was recorded in 29 (15%. Vaccination coverage was >75% for tetanus-diphtheria, pneumococcal and quadrivalent meningitis but was only 70.4% for influenza. After returning, 41 (13.5% pilgrims reported some health problem; of these, 61% were respiratory tract symptoms. The risk factors independently correlated with the presence of diseases was the number of days in Saudi Arabia (OR=1.06; 95% CI: 1.01-1.11 and taking part in the Hajj compared with the Umra (OR=1.08; 95% CI: 1.07-1.12. Conclusions: Religious pilgrims from Spain to Saudi Arabia are mainly young and healthy. Those with longer stays abroad contracted a higher number of diseases.

  19. Evidence for a GVL effect following reduced-intensity allo-SCT in ALL: a British Society of Blood and Marrow Transplantation study.

    Science.gov (United States)

    Medd, P G; Peniket, A J; Littlewood, T J; Pearce, R; Perry, J; Kirkland, K E; Shaw, B E; Potter, M N; Craddock, C F; Milligan, D W; Fielding, A K; Marks, D I; Cook, G

    2013-07-01

    Myeloablative allo-SCT decreases relapse incidence (RI) in ALL. Reduced intensity conditioning (RIC) may extend allo-SCT to older and less fit patients. Sixty-nine ALL patients reported to the BSBMT underwent fludarabine-based RIC allo-SCT, 38 from unrelated donors (UD). Forty-four patients received alemtuzumab. ALL was in CR in 64 patients (93%). This was a second or third SCT in 23 patients. Two-year OS and PFS were 36% and 32%, respectively. In multivariate analysis male recipients demonstrated better OS and PFS (hazard ratio (HR) = 0.42, P = 0.008 and HR = 0.45, P = 0.012, respectively). Two-year TRM was 29%: higher with younger age (HR = 0.97/year, P = 0.041), female recipient (HR = 2.55, P = 0.049) and increasing grade of acute GVHD (HR = 1.87, P = 0.001). Two-year RI was 38% and was lower in patients with acute and chronic GVHD (HR = 0.62 per increasing grade, P = 0.035 and HR = 0.52, P = 0.025, respectively). Long-term ALL-free survival is achievable following fludarabine-based RIC allo-SCT. The association between GVHD and decreased RI suggests the presence of a GVL effect.

  20. From the Roman and then Longobard via Cassiola to the Piccola Cassia Tourist Project

    Directory of Open Access Journals (Sweden)

    Paola Foschi

    2017-12-01

    Full Text Available A coordinated set of initiatives of cultural value also useful for the acquaintance and tourism development of the territory must have as solid basis the study of the ancient testimonies of the path of travelers and pilgrims. Cassiola road was a Roman road, continuing north of Cassia road, disused during the occupation of the Longobards of West Emilia, and reopened by the longobard king Astolfo in the middle of the eighth century. Today the different stretches of Cassiola or Piccola Cassia road are still accessible on foot, on horseback, by bicycle, and touch places of high historical, architectural, artistic and cultural value. The study of many other medieval roads deriving from Roman ones has verified the persistence of the use of the road name itself (such as Fiamenga da Flaminia or Cassiola da Cassia or the use in medieval documents of the term strata, which always indicates a road of importance not only local but at least regional or trans-regional. Via Cassiola can be found in medieval documents from this name, in the vulgar Latin transformed into Cassola, or in the historical cartography of Modern age with the name of Cassola or Cassoletta. Its path to the plain between Modena and Bologna covered important Benedictine abbeys rich in relics, such as S. Silvestro di Nonantola and S. Maria in Strada, and medieval hospitals for pilgrims, such as S. Bartholomew of Spilamberto. On the hills, the road touched the abbey of St. Lucia of Roffeno and wandered the Apennine to the passage of the Arcane Cross, where a great cross was driving the passengers. On the way to the pass, pilgrims could stay at the church of S. Colombano in Fanano, while in the valley of the Ospitale torrent one could find refuge in the hospice of S. Giacomo of Val di Lamola, both still existing. In Tuscany, the road allowed to arrive in Pistoia, the end of the Roman Cassia road, where pilgrims could adore the relics of saint James in the cathedral, or reach the Garfagnana

  1. Reinventing Organisations and the Future of Work

    CERN Multimedia

    CERN. Geneva

    2016-01-01

    Frédéric Laloux works as an adviser, coach, and facilitator for corporate leaders who feel called to explore fundamentally new ways of organizing. A former associate partner with McKinsey & Co., he holds an MBA from INSEAD. Frédéric Laloux is the author of the much talked about book "Reinventing Organizations". His fundamental research in the field of emerging organizational models has been described as ground-breaking, brilliant, spectacular, impressive, and world changing by some of the most respected scholars in the field of human development. youtu.be/gcS04BI2sbk

  2. Inmigrantes en formación : estado de bienestar y promoción de lazos sociales en el caso de la formación para la inserción laboral de las personas inmigrantes en Barcelona

    OpenAIRE

    Yufra, Laura Cristina

    2013-01-01

    La tesi constitueix un recorregut teòric-empíric al voltant de la configuració sociopolítica del fenomen de la immigració com "problema d'Estat" a partir de l'estudi del cas de la formació per a la inserció laboral. S'assenyala la intrínseca relació entre immigració i Estat i s'identifiquen els processos de transformació en la promoció dels llaços socials per part de l'anomenat Estat "de benestar". En el desenvolupament del treball s'analitza l'accés als recursos de formació de les persones i...

  3. [Methodologies of publications in the Revista de Investigación Clínica during the last 20 years].

    Science.gov (United States)

    López-Jiménez, F; Borovoy, J

    1997-01-01

    To characterize the clinical research methods published in the Revista de Investigación Clínica for the past 20 years. Comparative study of methods used in the RIC articles published in 3-years periods representing three decades (1972-74, 1982-84, 1992-94). Out of 273 original papers, 218 (80%) were of clinical research. There was an increased percentage of longitudinal vs cross-sectional studies, with cohort and randomized clinical trials showing the largest increase. The total number of research manuscripts also increased. The clinical research methods of the papers in the RIC have shown an increased rate of designs with a higher scientific value.

  4. Effect of electrodes in the radiation induced conductivity for polymers

    International Nuclear Information System (INIS)

    Gregorio Filho, R.; Gross, B.

    1988-01-01

    Samples of PET with 23 μm thickness were exposed to continuous X-rays and the radiation-induced conductivity (RIC) as a function of time were measured, using electrodes of evaporated aluminum and gold. The results showed that the use of higher atomic number metal electrodes increase the received dose rate by sample, without almost modifying the time evolution of the RIC or its dependence with the applied electric field intensity. It is also showed that this increase is caused by the electrode placed in the face of the sample where the radiation strikes, as well as by the one placed in the oposite face. (author) [pt

  5. 77 FR 75065 - Rescinding Spent Fuel Pool Exclusion Regulations

    Science.gov (United States)

    2012-12-19

    ... of the environmental impact analysis and severe accident mitigation alternatives (SAMA) analysis... subpart A, appendix B], because * * * many of the implications of the Fukushima accident for the Pilgrim... plant (NPP), in light of significant new information revealed by the Fukushima accident.'' The...

  6. Types Of Christian Tourism

    Directory of Open Access Journals (Sweden)

    Cornelia Petroman

    2015-10-01

    Full Text Available Christian tourism is asub-type of tourism where pilgrims travel alone or in group as missionaries orpilgrims or to spend their free time to recollect; it attracts a large numberof travellers. Christian tourism can be practiced by religious young people,missionaries, participants to religious convents, amateurs of religiouscruises, religious camps, visitors of religious attractions, religiousadventurers. Christian tourism can be considered a sub-type of religioustourism because of the large number of people involved in this type of tourismworldwide. Christian tourism as a sub-category of religious tourism coversthree main sub-types: traditional pilgrimage practiced by most world religions,missionary travel to different areas in the world, and confessional voyage. Thestructure of hospitality industry is common to all types of tourism but, fortraditional pilgrimage, there must be special places for the pilgrims to sleep,eat and pray, because they belong, in most cases, to the medium-income touristcategory.

  7. Pattern of diseases among visitors to Mina health centers during the Hajj season, 1429 H (2008 G).

    Science.gov (United States)

    Alzahrani, Abdullah G; Choudhry, Abdul Jamil; Al Mazroa, Mohammad A; Turkistani, Abdul Hafiz M; Nouman, Ghassan S; Memish, Ziad A

    2012-03-01

    While performing the Hajj, hajjis face different risks related to the environment, their behaviors and their health conditions that can result in a variety of diseases. The objective of this study was to determine the pattern of diseases among pilgrims seeking medical services in Mina primary health care centers (PHCCs) during the Hajj season in 1429 (2008). This is a descriptive study based on the medical records of a random sample of 4136 patients who attended 13 randomly selected Mina PHCCs from 8 to 12 Dhu-Alhijja, 1429 H (6-10 December 2008). The majority of the patients were men (70.7%), and most of the patients were between 45 and 64 years of age (42.8%). One-fifth (20.2%) of the patients suffered from multiple diseases. Respiratory diseases were the most common (60.8%), followed by musculoskeletal (17.6%), skin (15.0%) and gastrointestinal (13.1%) diseases. Diabetes, asthma and hypertension each constituted less than 3% of the total diseases. Respiratory diseases were the most common independent of nationality or the day of visit, while the frequency of the other diseases varied according to nationality and the day of visit. The most frequently prescribed drugs were analgesics, antipyretics, antibiotics and cough syrups. This study describes the pattern of diseases among pilgrims attending Mina PHCCs, which may aid in providing the best possible health care services to pilgrims. Copyright © 2011 King Saud Bin Abdulaziz University for Health Sciences. Published by Elsevier Ltd. All rights reserved.

  8. Norovirus disease associated with excess mortality and use of statins : A retrospective cohort study of an outbreak following a pilgrimage to Lourdes

    NARCIS (Netherlands)

    Rondy, M.; Koopmans, M.; Rotsaert, C.; van Loon, T.; Beljaars, B.; van Dijk, G.; Siebenga, J.; Svraka, S.; Rossen, J. W. A.; Teunis, P.; van Pelt, W.; Verhoef, L.

    Although norovirus infection is generally known to be a mild disease, there is some evidence for severe outcome. An outbreak in a Dutch psychiatric institution, originating from pilgrims returning from Lourdes (France), provided an opportunity for performing a retrospective cohort study in order to

  9. Toward the Validation of Depth-Averaged Three Dimensional, Rans Steady-State Simulations of Fluvial Flows at Natural Scale

    Science.gov (United States)

    Mateo Villanueva, P. A.; Hradisky, M.

    2010-12-01

    Simulations of fluvial flows are strongly influenced by geometric complexity and overall uncertainty on measured flow variables, including those assumed to be well known boundary conditions. Often, 2D steady-state models are used for computational simulations of flows at the scale of natural rivers. Such models have been successfully incorporated in iRIC (formerly MD_SWMS), one of the widely used quasi-3D CFD solvers to perform studies of environmental flows. iRIC aids in estimating such quantities as surface roughness and shear stress, which, in turn, can be used to estimate sediment transport. However, the computational results are inherently limited in accuracy because of restricting the computations to 2D, or quasi-3D, space, which can affect the values of these predictions. In the present work we perform computer-based simulations of fluvial flows using OpenFOAM, a free, open source fully 3D CFD software package, and compare our results to predictions obtained from iRIC. First, we study the suitability of OpenFOAM as the main CFD solver to analyze fluvial flows and validate our results for two well documented rectangular channel configurations: the first case consists of a large aspect-ratio channel (ratio of depth over width 0.017, ratio of depth over length 0.0019) with a rectangular obstacle mounted at the bottom wall; the second case involves a large aspect-ratio channel (ratio of depth over width 0.1, ratio of depth over length 0.0025) with cubic obstacles mounted at the lower wall (one obstacle) and upper wall (two obstacles). Secondly, we apply our model to simulation or river at natural scale and compare our results to the output obtained from iRIC to quantify the differences in velocity profiles and other flow parameters when comparable solution techniques are used. Steady-state, RANS k-epsilon models are employed for all simulations.

  10. Microbiology of a wetland ecosystem constructed to remediate mine drainage from a heavy metal mine.

    Science.gov (United States)

    Hallberg, Kevin B; Johnson, D Barrie

    2005-02-01

    A pilot passive treatment plant (PPTP) was constructed to evaluate the potential of a composite wetland system to remediate acidic, metal-rich water draining the former Wheal Jane tin, in Cornwall, England. The treatment plant consists of three separate and controllable composite systems, each of which comprises a series of aerobic wetlands for iron oxidation and precipitation, a compost bioreactor for removing chalcophilic metals and to generate alkalinity, and rock filter ponds for removing soluble manganese and organic carbon. To understand the roles of microorganisms in remediating acid mine drainage (AMD) in constructed wetland ecosystems, populations of different groups of cultivatable acidophilic microbes in the various components of the Wheal Jane PPTP were enumerated over a 30-month period. Initially, moderately acidophilic iron-oxidising bacteria (related to Halothiobacillus neapolitanus) were found to be the major cultivatable microorganisms present in the untreated AMD, though later heterotrophic acidophiles emerged as the dominant group, on a numerical basis. Culturable microbes in the surface waters and sediments of the aerobic wetlands were similarly dominated by heterotrophic acidophiles, though both moderately and extremely acidophilic iron-oxidising bacteria were also present in significant numbers. The dominant microbial isolate in waters draining the anaerobic compost bioreactors was an iron- and sulfur-oxidising moderate acidophile that was closely related to Thiomonas intermedia. The acidophiles enumerated at the Wheal Jane PPTP accounted for 1% to 25% of the total microbial population. Phylogenetic analysis of 14 isolates from various components of the Wheal Jane PPTP showed that, whilst many of these bacteria were commonly encountered acidophiles, some of these had not been previously encountered in AMD and AMD-impacted environments.

  11. Sugarcane root length density and distribution from root intersection counting on a trench-profile Densidade de comprimento e distribuição de raízes de cana-de-açúcar a partir da contagem de intersecção de raízes na parede do perfil

    Directory of Open Access Journals (Sweden)

    Mateus Carvalho Basilio de Azevedo

    2011-02-01

    Full Text Available Root length density (RLD is a critical feature in determining crops potential to uptake water and nutrients, but it is difficult to be measured. No standard method is currently available for assessing RLD in the soil. In this study, an in situ method used for other crops for studying root length density and distribution was tested for sugarcane (Saccharum spp.. This method involved root intersection counting (RIC on a Rhodic Eutrudox profile using grids with 0.05 x 0.05 m and modeling RLD from RIC. The results were compared to a conventional soil core-sampled method (COR (volume 0.00043 m³. At four dates of the cropping season in three tillage treatments (plowing soil, minimum tillage and direct planting, with eight soil depths divided in 0.1 m soil layer (between 0-0.6 and 1.6-1.8 m and three horizontal distances from the row (0-0.23, 0.23-0.46 and 0.46-0.69 m, COR and RIC methods presented similar RLD results. A positive relationship between COR and RIC was found (R² = 0.76. The RLD profiles considering the average of the three row distances per depth obtained using COR and RIC (mean of four dates and 12 replications were close and did not differ at each depth of 0.1 m within a total depth of 0.6 m. Total RLD between 0 and 0.6 m was 7.300 and 7.100 m m-2 for COR and RIC respectively. For time consumption, the RIC method was tenfold less time-consuming than COR and RIC can be carried out in the field with no need to remove soil samples. The RLD distribution in depth and row distance (2-D variability by RIC can be assessed in relation to the soil properties in the same soil profiles. The RIC method was suitable for studying these 2-D (depth and row distance in the soil profile relationships between soil, tillage and root distribution in the field.A densidade de comprimento de raízes (DCR é uma característica importante para determinar o potencial de absorção de água e nutrientes das plantas, mas é difícil de ser medida. Nenhum m

  12. The Impact of the Feminist Heroine: Elizabeth in Pride and Prejudice

    Directory of Open Access Journals (Sweden)

    Hui-Chun CHANG

    2014-05-01

    Full Text Available This paper critically examines the feminist significance of Elizabeth Bennet, heroine of Jane Austen’s Pride and Prejudice. The feminist view found in Pride and Prejudice is well-supported in literary criticism yet little discussion has focused on Elizabeth’s feminism as seen in the prominent contrast to her female foils within the novel, namely Caroline, Jane, and Charlotte. Each of these women conforms to the socially imposed gender norms of Regency England, while Elizabeth artfully challenges gender inequality. As other women adapt their views to increase their chances of marriage, Elizabeth persistently refuses to capitulate. Defying traditional gender norms, Elizabeth affirms her feminist perspective by helping to shape Mr. Darcy’s moral character to match her own. Elizabeth inspires Mr. Darcy to set aside the pride he has in his high station in society in order to win her affections and take her hand in marriage. I argue that Elizabeth’s character is not feminist in isolation, but is understood only in contrast to Caroline, Jane, and Charlotte. This claim is supported by an in-depth comparison of Elizabeth and each of the female foils.

  13. Mémoires et conflits: Conflits des mémoires, collision des durées

    Directory of Open Access Journals (Sweden)

    Jean-Louis Vieillard-Baron

    2014-01-01

    Full Text Available There is a collision between the durations and between the memories, every time that duration rythms are different. For Bergson there is a difference of degrees of tension between durations but the flow is unique. Ricœur distinguishes many degrees of passeity according to the proximity or the distance. As example he sets the Zauberberg of Thomas Mann. Forgetting and Forgiveness are forms of durations collision. The distensio animi of Saint Augustine means dissipation  Ricœur misunderstands this expression what means for him phenomenological intratemporality, and he goes no further than tearing of soul distant from eternity. Normal 0 false false false EN-US JA X-NONE

  14. Preparation and preclinical evaluation of 211At-labelled compounds for α-particle radiotherapy

    International Nuclear Information System (INIS)

    Larsen, R.H.

    1994-01-01

    The present work demonstrate that significant therapeutic gain can be achieved with 211 At-labelled MoAbs on single tumour cells and microscopic disease. Β-emitters are less effective on microscopic disease because of radiation dispersion, while longer halflives (e.g., 90 Y and 131 I) allow favourable therapeutic ratios to be reached in larger tumors. 211 At-labelled MoAbs may therefore possibly be used in combination with β-emitting RIC in systemically delivered radioimunnotherapy. Larger tumor nodules are then irradiated effectively due to cross-fire of the longer ranged β-particles while the fraction of tumour cells distributed as single cells and micrometastases may be more effectively radiated with 211 At-RIC. 76 refs

  15. Heat recovery from beer and groundwater; Waermegewinnung aus Bier und Grundwasser

    Energy Technology Data Exchange (ETDEWEB)

    Sinn, Ruediger

    2009-04-15

    A conference and tourist hotel was constructed near the pilgrim chapel of St. Afra near Augsburg. The cost of heating and cooling was to be kept as low as possible. The problem was solved by a water-to-water heat pump and further energetic optimisations. (orig.)

  16. 77 FR 74694 - Notice of January 14, 2013, Meeting for Cape Cod National Seashore Advisory Commission

    Science.gov (United States)

    2012-12-17

    ... Wind Turbines/Cell Towers Shorebird Management Planning Highlands Center Update Alternate... Parks 6. Old Business Emergency Evacuation and the Pilgrim Nuclear Plant 7. New Business 8. Date and... purpose of the Commission is to consult with the Secretary of the Interior, or his designee, with respect...

  17. La atracción turística de un espacio mítico: peregrinación al cabo de Finisterre

    Directory of Open Access Journals (Sweden)

    Herrero, Nieves

    2009-04-01

    Full Text Available This article analyzes the production of the “sense of place” of Finisterre - Cape situated in the Autonomous Community of Galicia (Spain - and the way it is used to promote its namesake village as a tourist destination. The essay highlights the global and local factors as well as the plurality of social actors that intervene in this process and their different interests and actions. Moreover, it shows the role played in this by the mythic narrative created by the forerunners of the Galician nationalist tradition who identified Galicia as an Atlantic Land´s End. This narrative allowed actors to propose this village as the goal of the pilgrimage to Saint James of Compostela so that it could benefit from the tourist promotion of Galicia largely based on the cultural heritage of the Pilgrim´s Way. The meaning of this place today is related to a secularised experience of the pilgrimage and to the pilgrims ritual practices inspired in the aforesaid myth.

  18. Enteric Infections Circulating during Hajj Seasons, 2011–2013

    KAUST Repository

    Abd El Ghany, Moataz; Alsomali, Mona; Almasri, Malak; Padron Regalado, Eriko; Naeem, Raeece; Tukestani, AbdulHafeez; Asiri, Abdullah; Hill-Cawthorne, Grant A.; Pain, Arnab; Memish, Ziad A.

    2017-01-01

    Hajj, the annual Muslim pilgrimage to Mecca, Saudi Arabia, is a unique mass gathering event that raises public health concerns in the host country and globally. Although gastroenteritis and diarrhea are common among Hajj pilgrims, the microbial etiologies of these infections are unknown. We collected 544 fecal samples from pilgrims with medically attended diarrheal illness from 40 countries during the 2011-2013 Hajj seasons and screened the samples for 16 pathogens commonly associated with diarrheal infections. Bacteria were the main agents detected, in 82.9% of the 228 positive samples, followed by viral (6.1%) and parasitic (5.3%) agents. Salmonella spp., Shigella/enteroinvasive Escherichia coli, and enterotoxigenic E. coli were the main pathogens associated with severe symptoms. We identified genes associated with resistance to third-generation cephalosporins approximate to 40% of Salmonella- and E. coli-positive samples. Hajj-associated foodborne infections pose a major public health risk through the emergence and transmission of antimicrobial drug-resistant bacteria.

  19. Enteric Infections Circulating during Hajj Seasons, 2011–2013

    KAUST Repository

    Abd El Ghany, Moataz

    2017-09-13

    Hajj, the annual Muslim pilgrimage to Mecca, Saudi Arabia, is a unique mass gathering event that raises public health concerns in the host country and globally. Although gastroenteritis and diarrhea are common among Hajj pilgrims, the microbial etiologies of these infections are unknown. We collected 544 fecal samples from pilgrims with medically attended diarrheal illness from 40 countries during the 2011-2013 Hajj seasons and screened the samples for 16 pathogens commonly associated with diarrheal infections. Bacteria were the main agents detected, in 82.9% of the 228 positive samples, followed by viral (6.1%) and parasitic (5.3%) agents. Salmonella spp., Shigella/enteroinvasive Escherichia coli, and enterotoxigenic E. coli were the main pathogens associated with severe symptoms. We identified genes associated with resistance to third-generation cephalosporins approximate to 40% of Salmonella- and E. coli-positive samples. Hajj-associated foodborne infections pose a major public health risk through the emergence and transmission of antimicrobial drug-resistant bacteria.

  20. Pilgrims, Pumpkins, and Turkeys: A Thanksgiving Bounty!!!

    Science.gov (United States)

    Byerly, Greg; Brodie, Carolyn S.

    1999-01-01

    Describes several Thanksgiving Web sites, including those with historical information, favorite Thanksgiving foods and recipes, songs and games, arts and crafts activities, and some sites "just for fun." Sites include everything from the Macy's Day Parade site, to PlimothonWeb, to Thanksgiving clip art. (AEF)

  1. Allogeneic Hematopoietic Cell Transplantation for Older Patients: Prognosis Determined by Disease Risk Index.

    Science.gov (United States)

    He, Fiona; Cao, Qing; Lazaryan, Aleksandr; Brunstein, Claudio; Holtan, Shernan; Warlick, Erica; Ustun, Celalettin; McClune, Brian; Arora, Mukta; Rashidi, Armin; Eckfeldt, Craig; Weisdorf, Daniel J; Bejanyan, Nelli

    2017-09-01

    The treatment of elderly patients with advanced hematological malignancies has expanded to include reduced-intensity conditioning (RIC) allogeneic hematopoietic cell transplantation (alloHCT) as a potentially curative option. We studied the association between Disease Risk Index (DRI) and clinical outcomes of 196 elderly patients (median age, 64.8; range, 60 to 75 years) with hematological malignancies receiving RIC alloHCT (2000 to 2014). Donors were related and unrelated adults (n = 100, 51.1%) or umbilical cord blood (n = 96, 48.9%). DRI classified 12 patients (6.1%) as low risk (LR), 146 patients (74.5%) as intermediate risk (IR), and 38 patients (19.4%) as high risk (HR). Two-year overall survival (OS) was 47% (52% for LR/IR versus 29% for HR, P risk of relapse (hazard ratio, 2.07; 95% confidence interval [CI], 1.34 to 3.33; P = .02) and treatment failure (hazard ratio, 2.07; 95% CI, 1.35 to 3.18; P risk of relapse leading to poor survival in HR DRI, participation in clinical trials offering relapse prevention strategies after RIC alloHCT should be encouraged when available. Copyright © 2017 The American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.

  2. Measurements of Prompt Radiation-Induced Conductivity of Pyralux®

    Energy Technology Data Exchange (ETDEWEB)

    Hartman, E. Frederick [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Radiation Effects Experimentation Dept.; Zarick, Thomas Andrew [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Radiation Effects Experimentation Dept.; McLain, Michael Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Radiation Effects Experimentation Dept.; Sheridan, Timothy J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Radiation Effects Experimentation Dept.; Preston, Eric F. [ITT Exelis, Colorado Springs, CO (United States); Stringer, Thomas Arthur [ITT Exelis, Colorado Springs, CO (United States)

    2014-01-01

    In this report, measurements of the prompt radiation-induced conductivity (RIC) in 3 mil samples of Pyralux® are presented as a function of dose rate, pulse width, and applied bias. The experiments were conducted with the Medusa linear accelerator (LINAC) located at the Little Mountain Test Facility (LMTF) near Ogden, UT. The nominal electron energy for the LINAC is 20 MeV. Prompt conduction current data were obtained for dose rates ranging from ~2 x 109 rad(Si)/s to ~1.1 x 1011 rad(Si)/s and for nominal pulse widths of 50 ns and 500 ns. At a given dose rate, the applied bias across the samples was stepped between -1500 V and 1500 V. Calculated values of the prompt RIC varied between 1.39x10-8 Ω-1 · m-1 and 2.67x10-7 Ω-1 · m-1 and the prompt RIC coefficient varied between 1.25x10-18 Ω-1 · m-1/(rad/s) and 1.93x10-17 Ω-1 · m-1/(rad/s).

  3. Technology Integration with Teacher Candidates in a Summer-Camp Setting

    Science.gov (United States)

    Pilgrim, Jodi; Berry, Joan

    2014-01-01

    Many districts have implemented one-to-one technology initiatives, where students have access to computers or tablets for use in and out of school. Teachers participating in these initiatives may lack knowledge about ways to integrate technology into classroom practices (Pilgrim and Bledsoe, 2012); therefore, teacher preparation programs must…

  4. Mida tulevikuga peale hakata? / Arko Olesk

    Index Scriptorium Estoniae

    Olesk, Arko, 1981-

    2014-01-01

    Arvustus: Kaku, Michio. Tulevikufüüsika : kuidas teadus aastal 2100 kujundab inimsaatust ja meie igapäevast elu / tlk. Arko Olesk. Tallinn : Pilgrim, 2013 ; Stevenson, Mark. Optimisti teekond tulevikku : üks uudishimulik sell tahab teada: mis saab edasi? / tlk. Vahur Lokk. Tallinn : Äripäev, 2013

  5. Bønner og burgere

    DEFF Research Database (Denmark)

    Rytter, Mikkel

    2013-01-01

    Based on a number of burger incidents during ten days of itikaf at a Sufi astana (lodge) in Pakistan, this article discusses religious self-cultivation among Muslim pilgrims from Denmark. The focus on food and eating is not only used to discuss how religious brotherhoods and spiritual kinship...

  6. ‘When Going to Saint James’: An Old Russian Graffito from the 12th Century in Aquitania

    Directory of Open Access Journals (Sweden)

    Alexander M. Gordin

    2016-08-01

    Full Text Available In 2015 in Pons, in the former province of Saintonge, an Old Russian pilgrim graffito was found on the wall of the parish church of St. Vivien, a monument of the mid-12th century. It is the second graffito found in France after the one discovered at St. Gilles Abbey. The town of Pons is located on the westernmost route of Santiago de Compostela (via Turonensis and is noteworthy because of the preserved pilgrim almshouse of the latter half of the 12th century. On the walls of its long archway are horseshoe drawings made by medieval pilgrims, the latest of which, dating from the 16th–17th centuries, bends around a name that is also apparently written in Cyrillic script. The earlier inscription, which appears at the base of the northern end wall of the original façade of the St. Vivien church, is made in the name of one Ivan Zavidovich: “Ivano ps[а]lo Zavi|doviche ida ko | svętomu Ię|kovu” (= ‘Ivan Zavidovich wrote this when going to Saint James’. The most probable palaeographic dating is in the 1160s–1180s. As suggested by birch bark manuscripts, the name of Ivan’s father, Zavid, was popular among Novgorod boyars. Novgorod is also the place with the greatest indirect evidence of the occurrence in Old Russia of the western cult of St. James. This well preserved inscription is an important epigraphic discovery, but its main value lies in the direct evidence of pilgrimages by Russians to the shrine of St. James in Galicia.

  7. 75 FR 22095 - Notice of Funds Availability for the Section 533 Housing Preservation Grants for Fiscal Year 2010

    Science.gov (United States)

    2010-04-27

    ... Hancock Avenue Athens, Georgia 30601-2768 (706) 546-2164 TDD (706) 546-2034 Dawn Pilgrim Hawaii State Office (Services all Hawaii, American Samoa, Guam, and Western Pacific) Room 311, Federal Building 154 Waianuenue Avenue Hilo, Hawaii 96720 (808) 933-8300 TDD (808) 933-8321 Gayle Kuheana Idaho State Office Suite...

  8. “I Think They All Felt Distressed!” Talking about Complex Issues in Early Childhood

    Science.gov (United States)

    Bentley, Dana; Reppucci, Anthony

    2013-01-01

    The Thanksgiving Day holiday celebrated in the United States is generally traced to a first harvest celebration in the newly established Plymouth colony (present-day Massachusetts). Traditional storytelling describes the first Thanksgiving feast as having been attended by 53 Pilgrims (the European settlers) and 90 Native Americans. The holiday can…

  9. Intimidation, reassurance and invisibility: Israeli security agents in the Old City of Jerusalem

    NARCIS (Netherlands)

    Grassiani, E.; Volinz, L.

    2016-01-01

    Jerusalem is a city of extremes, where tourists and pilgrims come to see the sights and pray, but where violence is also a daily affair. In the square kilometer called the Old City, which is part of East Jerusalem and thus considered by the international community as occupied territory, the tensions

  10. New England Takes Stock of Midterm Elections

    Science.gov (United States)

    Harney, John O.; Morwick, Carolyn

    2014-01-01

    The recent midterm elections brought New England two new governors. Rhode Island elected its first woman chief executive in Gina Raimondo (D). Massachusetts elected Charlie Baker (R), a former Harvard Pilgrim CEO and official in the Weld and Cellucci administrations. Otherwise, the New England corner offices cautiously welcomed back incumbents:…

  11. QUEL CHE RESTA DELLA PSICANALISI. UNA LETTURA MERLEAU‐PONTIANA DI FREUD

    Directory of Open Access Journals (Sweden)

    Scotti, Alessandra

    2015-12-01

    Full Text Available This paper investigates Maurice Merleau‐Ponty’s interest about Freud’s philosophical works. It invokes the Freud’s recognition as “Master of the School of suspicion”, a famous definition made by Paul Ricœur. According to Ricœur, Freud’s theories take place within the philosophical stream that looks at “constituted cogito” with deep mistrust. Through the analysis of “Phenomenology of Perception” we can observe the accusation of “pansexuality” moved by Merleau‐Ponty. However, as Merleau‐ Ponty’s philosophy develops and his view changes from “existential” to “ontological”, the relation between Freud and Merleau‐Ponty changes accordingly, until the acknowledgment of the unconscious as a prediction of the “chair”.

  12. Magneto-optical properties in inhomogeneous quantum dot: The Aharonov-Bohm oscillations effect

    Energy Technology Data Exchange (ETDEWEB)

    Nasri, Djillali, E-mail: nasri_dj@yahoo.fr [Faculté des Sciences Appliquées, Département de Génie Electrique, Université Ibn-Khaldoun de Tiaret, Zaaroura BP No. 78, Tiaret 14000 (Algeria); Laboratoirede Microphysique et de Nanophysique (LaMiN), Ecole Nationale Polytechnique d' Oran, BP 1523EL M' Naouer, Oran 31000 (Algeria); Bettahar, N. [Faculté des Sciences de la matière, Département de Physique, Université Ibn-Khaldoun de Tiaret, Zaaroura BP No. 78, Tiaret 14000 (Algeria)

    2016-11-15

    In this study, we investigated theoretically the effect of a magnetic field B on the linear, nonlinear, and total absorption coefficients (ACs) and the refractive index changes (RICs) associated with intersubband transitions in the HgS quantum shell. In the calculations, a diagonalization method was employed within the effective-mass approximation. We find that a three kinds of optical transitions (S–P, P–D and D–F) between the ground state and the first excited state appear, resulting from the oscillation of the ground state with B (Aharonov-Bohm effect). In the other hand, the magnetic field enhances and diminishes their related RICs and ACs intensities respectively for the three kinds of optical transitions, and shifts their peaks towards low energy (blue shift).

  13. 'It was a Sweet View - Sweet to The Eye and The Mind.'

    DEFF Research Database (Denmark)

    Knudsen, Karin Esmann

    2017-01-01

    It is obvious in Jane Austen’s novels that she was interested in the ongoing debate of ’the picturesque garden’, and in all her novels the characters are discussing how to look at the landscape, how to ‘improve’ the estates according to certain rules, and how taste and moral are connected to each...... from modern films based on Jane Austen’s novels....... these topoi, which are ideal landscapes that only exist in literature and painting, and the discussions of the design of real physical landscapes of contemporary England. It is difficult to decide on which side Austen was in the discussions of the picturesque. The article concludes that Austen’s voice...

  14. Dgroup: DG00872 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available DG00872 Chemical ... DGroup Cyamemazine ... D07307 ... Cyamemazine (INN) D07756 ... Cyamemazine tartrate Neuropsychiat...ric agent ... DG01905 ... Phenothiazine antipsychotics ATC code: N05AA06 Phenothiazine antipsychotics ...

  15. Moodne aeg käib alla / Valner Valme

    Index Scriptorium Estoniae

    Valme, Valner, 1970-

    2008-01-01

    Arvustus: Beigbeder, Frédéric. Armastus kestab kolm aastat : romaan / prantsuse keelest tõlkinud Anti Saar. Tallinn : Varrak, 2008 ; Cusk, Rachel. Arlington Park / tõlkinud Kersti Unt. Tallinn : Varrak, 2007

  16. Caracterisation des dechets solides des grandes manifestations ...

    African Journals Online (AJOL)

    This situation aggravates the structural inadequacy of the city managers and leads to unsanitary. The content of a pilgrim's trash behaves like a mirror reflecting his consumption habits, his attitude towards a manifestation of piety in the public space considered as private area as well as a no man's land. Keywords: Dassa ...

  17. Chrysalis

    Science.gov (United States)

    Marsh, John

    1977-01-01

    In an outpouring of metaphysical anguish, Adrian Redman exhorts his companion, his own pilgrim self, and an uncompassionate society to forego the dichotomy of creativity/conformity--the necessity of absolute choice--in favor of spontaneity, freedom, and joy in the unique development of each individual from a (metaphorical) pupa to a butterfly.…

  18. Estonia juhti kahtlustatakse ettevõtte varade omastamises / Ester Vilgats, Eno-Gerrit Link, Teet Roosaar

    Index Scriptorium Estoniae

    Vilgats, Ester

    2008-01-01

    Endine Pärnu linnapea, taastusravikeskuse Estonia pikaaegne juht Vello Järvesalu peeti kinni kahtlustatuna ettevõtte varade omastamises suures ulatuses. Kommenteerivad: Mart Viisitamm, Jane Mets ja Ahti Kõo

  19. Ideaalse ja vulgaarse maailma kokkupõrge / Johannes Saar

    Index Scriptorium Estoniae

    Saar, Johannes, 1965-

    2005-01-01

    Briti kaasaegse kunsti valiknäitus "Supernoova" Tallinna Kunstihoones. Kuraator on Caroline Douglas. Osalevad Jane ja Louise Wilson, Haluk Akakce, Richard Wright, Toby Ziegler, Sarah Morris, Keith Coventry

  20. Store turnover as a predictor of food and beverage provider turnover and associated dietary intake estimates in very remote Indigenous communities.

    Science.gov (United States)

    Wycherley, Thomas; Ferguson, Megan; O'Dea, Kerin; McMahon, Emma; Liberato, Selma; Brimblecombe, Julie

    2016-12-01

    Determine how very-remote Indigenous community (RIC) food and beverage (F&B) turnover quantities and associated dietary intake estimates derived from only stores, compare with values derived from all community F&B providers. F&B turnover quantity and associated dietary intake estimates (energy, micro/macronutrients and major contributing food types) were derived from 12-months transaction data of all F&B providers in three RICs (NT, Australia). F&B turnover quantities and dietary intake estimates from only stores (plus only the primary store in multiple-store communities) were expressed as a proportion of complete F&B provider turnover values. Food types and macronutrient distribution (%E) estimates were quantitatively compared. Combined stores F&B turnover accounted for the majority of F&B quantity (98.1%) and absolute dietary intake estimates (energy [97.8%], macronutrients [≥96.7%] and micronutrients [≥83.8%]). Macronutrient distribution estimates from combined stores and only the primary store closely aligned complete provider estimates (≤0.9% absolute). Food types were similar using combined stores, primary store or complete provider turnover. Evaluating combined stores F&B turnover represents an efficient method to estimate total F&B turnover quantity and associated dietary intake in RICs. In multiple-store communities, evaluating only primary store F&B turnover provides an efficient estimate of macronutrient distribution and major food types. © 2016 Public Health Association of Australia.

  1. Stable long-term pulmonary function after fludarabine, antithymocyte globulin and i.v. BU for reduced-intensity conditioning allogeneic SCT.

    Science.gov (United States)

    Dirou, S; Malard, F; Chambellan, A; Chevallier, P; Germaud, P; Guillaume, T; Delaunay, J; Moreau, P; Delasalle, B; Lemarchand, P; Mohty, M

    2014-05-01

    Lung function decline is a well-recognized complication following allogeneic SCT (allo-SCT). Reduced-intensity conditioning (RIC) and in vivo T-cell depletion by administration of antithymocyte globulin (ATG) may have a protective role in the occurrence of late pulmonary complications. This retrospective study reported the evolution of lung function parameters within the first 2 years after allo-SCT in a population receiving the same RIC regimen that included fludarabine and i.v. BU in combination with low-dose ATG. The median follow-up was 35.2 months. With a median age of 59 years at the time of transplant, at 2 years, the cumulative incidences of non-relapse mortality was as low as 9.7%. The cumulative incidence of relapse was 33%. At 2 years, the cumulative incidences of extensive chronic GVHD (cGVHD) and of pulmonary cGVHD were 23.1% and 1.9%, respectively. The cumulative incidences of airflow obstruction and restrictive pattern were 3.8% and 9.6%, respectively. Moreover, forced expiratory volume (FEV1), forced vital capacity (FVC) and FEV1/FVC ratio remained stable from baseline up to 2 years post transplantation (P=0.26, P=0.27 and P=0.07, respectively). These results correspond favorably with the results obtained with other RIC regimens not incorporating ATG, and suggest that ATG may have a protective pulmonary role after allo-SCT.

  2. A new approach for simple radioisotope cisternography examination in cerebrospinal fluid leakage detection.

    Science.gov (United States)

    Hoshino, Hiromitsu; Higuchi, Tetsuya; Achmad, Arifudin; Taketomi-Takahashi, Ayako; Fujimaki, Hiroya; Tsushima, Yoshito

    2016-01-01

    We developed a new quantitative interpretation technique of radioisotope cisternography (RIC) for the diagnosis of spontaneous cerebrospinal fluid hypovolemia (SCH). RIC studies performed for suspected SCH were evaluated. (111)In-DTPA RIC images were taken at 0, 1, 3, 6, and 24-h after radioisotope injection following the current protocol. Regions of interest (ROI) were selected on 3-h images to include brain, spine, bladder or the whole body. The accumulative radioactivity counts were calculated for quantitative analysis. Final diagnoses of SCH were established based on the diagnostic criteria recently proposed by Schievink and colleagues. Thirty-five patients were focused on. Twenty-one (60.0%) patients were diagnosed as having SCH according to the Schievink criteria. On the 3-h images, direct cerebrospinal fluid leakage sign was detected in nine of 21 SCH patients (42.9%), as well as three patients with suspected iatrogenic leakage. Compared to non-SCH patients, SCH patients showed higher bladder accumulation at 3-h images (P = 0.0002), and higher brain clearance between the 6- and 24-h images (P leakage was not observed. 1- and 6-h images did not provide any additional information in any patients. A new simple ROI setting method, in which only the 3-h whole body and 24-h brain images were necessary, was sufficient to diagnose SCH.

  3. Chronic whiplash-associated disorder and traumatic cerebrospinal fluid leak. Analysis of cases with radioisotope cisternography, epidural blood patch, and cervical facet joint blocks

    International Nuclear Information System (INIS)

    Ishikawa, Shinichi; Kobayashi, Hiroyuki; Takahara, Hiroshi; Kojo, Shigeru; Hashimoto, Hidenori; Moriyama, Eiji; Nishida, Ayumi

    2008-01-01

    This paper describes RI cisternographic (RIC) examinations of whiplash-associated disorder (WAD) and results of their treatment with nerve block and epidural blood patch (EBP) conducted in authors' facilities. Subjects were 40 chronic (av. symptomatic period of 3.1 y) WAD patients (av. age 34 y) with traffic (28 cases), sports (7) and falling (5) causes with complication of suspicious cerebrospinal fluid (CSF) leak. RIC was done 2.5-24 hr after injection of 37 MBq of 111 In-diethylenetriamine pentaacetic acid (DTPA) in the medullary space through epidural puncturing needle. Positive finding of clear leak or early accumulation of RI in the bladder was seen in 21 cases and negative, in 19. Positive patients had significantly higher rates of headache, abnormal vision and fatigue than negative ones. EBP was conducted through X-ray to all positive patients and to negative ones with strongly suspicious leak complication (7 cases), which resulted in improvement of symptoms like headache and vision in the former, but no improvement in the latter cases. Repeated RIC of the patients with poor improvement in the former was suggested effective for judgment of repetition of EBP treatment. Cervical facet joint blocks were found effective in cases with posterior cervical pain. Symptoms in WAD accompanying headache should be differentially diagnosed whether it is derived from posttraumatic CSF leak or from pain due to cervical facet arthritis. (R.T.)

  4. Marijuana intoxication

    Science.gov (United States)

    ... Intoxication - marijuana (cannabis); Pot; Mary Jane; Weed; Grass; Cannabis ... drugs that have more serious side effects than marijuana. These side effects may include: Sudden high blood pressure with headache ...

  5. Punane Veski ja plakatikunsti algus / Riina Robinson

    Index Scriptorium Estoniae

    Robinson, Riina

    2007-01-01

    Prantsuse plakatikunsti loojast Jules Cheret'st, ühest silmapaistvamast plakati- ja maalikunstnikust Henri Toulouse-Lautrecist, tema plakatite kangelannadest, kankaani tantsinud Louise Weberist ja Jane Avrilist ning Moulin Rouge'ist

  6. Hajj Transportation of Netherlands East Indies, 1910-1940

    Directory of Open Access Journals (Sweden)

    Erlita Tantri

    2016-01-01

    Full Text Available This article is about Hajj transportation of Netherland Indies in during the years of 1910-1940. The focus of this article is the mechanism of the Hajj transportation and its significance since eighteenth century. It is based on that historical phmomenon, that this paper will examine the hajj transportation in the past related to regulation and problem and why it was important to control hajj ship transportation by using archives and authorities' report as main sources and other secondary sources. Historically, since eighteenth century, even until today, going to hajj or pilgrimage was very interesting and attractive for native Muslim in Netherlands East Indies (Indonesia, especially for gaining religious requirement, social pride and Islamic ideas. The phenomenon can be seen from the increase and the stable number of the pilgrims from Indonesia which had attracted much interest from many parts of stake holders such as from Hijaz (Arabian government. In relation to that, it is worth noting that ship was an important transport to convey pilgrim from and to Indonesia and thus, business of hajj transportation become a field of contention between state authority and private ship businesses. It is based on that historical phenomenon, that this paper will examine the hajj transportation in the past related to regulation and problems and why it was important to control hajj ship transportation by using archives and authorities report as main sources and other secondary sources. Hajj transportation was a profitable business (even until today that increased competition among British, Malay, Arabic, and Dutch shipping companies. Completion and regulation from ships and authority did not give better services for native pilgrims besides poor condition, discomfort and suffering of pilgrimage. However, hajj transportation had to be controlled, especially to restrain problems of moekimans and movement ideas from Hijaz.

  7. Potential for the international spread of middle East respiratory syndrome in association with mass gatherings in saudi arabia.

    Science.gov (United States)

    Khan, Kamran; Sears, Jennifer; Hu, Vivian Wei; Brownstein, John S; Hay, Simon; Kossowsky, David; Eckhardt, Rose; Chim, Tina; Berry, Isha; Bogoch, Isaac; Cetron, Martin

    2013-07-17

    A novel coronavirus (MERS-CoV) causing severe, life-threatening respiratory disease has emerged in the Middle East at a time when two international mass gatherings in Saudi Arabia are imminent. While MERS-CoV has already spread to and within other countries, these mass gatherings could further amplify and/or accelerate its international dissemination, especially since the origins and geographic source of the virus remain poorly understood. We analyzed 2012 worldwide flight itinerary data and historic Hajj pilgrim data to predict population movements out of Saudi Arabia and the broader Middle East to help cities and countries assess their potential for MERS-CoV importation. We compared the magnitude of travel to countries with their World Bank economic status and per capita healthcare expenditures as surrogate markers of their capacity for timely detection of imported MERS-CoV and their ability to mount an effective public health response. 16.8 million travelers flew on commercial flights out of Saudi Arabia, Jordan, Qatar, and the United Arab Emirates between June and November 2012, of which 51.6% were destined for India (16.3%), Egypt (10.4%), Pakistan (7.8%), the United Kingdom (4.3%), Kuwait (3.6%), Bangladesh (3.1%), Iran (3.1%) and Bahrain (2.9%). Among the 1.74 million foreign pilgrims who performed the Hajj last year, an estimated 65.1% originated from low and lower-middle income countries. MERS-CoV is an emerging pathogen with pandemic potential with its apparent epicenter in Saudi Arabia, where millions of pilgrims will imminently congregate for two international mass gatherings. Understanding global population movements out of the Middle East through the end of this year's Hajj could help direct anticipatory MERS-CoV surveillance and public health preparedness to mitigate its potential global health and economic impacts.

  8. Heat from beer and groundwater. Energy concept; Waerme aus Bier und Grundwasser. Energiekonzept

    Energy Technology Data Exchange (ETDEWEB)

    Sinn, Ruediger

    2009-02-15

    In the neighbourhood of the Bavarian pilgrim's church of St. Afra im Felde near Augsburg, a conference and tourist hotel was projected and constructed within a very short period of time. The biggest challenge was to keep the energy cost for heating and cooling of the building as low as possible. (orig.)

  9. Increasing reliability of defect characterization on sg tubings using a combination of signal processing and expert system

    International Nuclear Information System (INIS)

    Benoist, B.; David, B.; Pigeon, M.

    1989-01-01

    An expert system is developed for automatic analysis of eddy current signals provided by the multifrequency control of steam generators tubing. This article describes on one hand the aim and the results of the elimination of pilgrim noise, on the other hand the expert system which uses signal analysis and signal processing in unison

  10. Christmas in Mexico.

    Science.gov (United States)

    Kern County Superintendent of Schools, Bakersfield, CA.

    The Christmas season in Mexico starts on December 16 with "las posadas," a series of religious processions in which families or neighbors reenact Joseph's search for shelter for Mary en route to Bethlehem. Those representing pilgrims travel from home to home until they are finally accepted by those representing innkeepers at a home with…

  11. Cooperation and trust essential to business / Gundar J King, Thad J Barnowe

    Index Scriptorium Estoniae

    King, Gundar J

    2001-01-01

    Muutuvas ühiskonnas vajatakse arenguga kaasa minemiseks traditsioonilist kapitali, inimkapitali ja sotsiaalset kapitali. Autorid uurisid Baltikumi ärikoolide õpilaste väärtusorientatsiooni, vaadeldakse Jane Jacobsi teoreetilist lähenemist

  12. Cooperation essential to the Baltics / Gundar J King, Thad Barnowe

    Index Scriptorium Estoniae

    King, Gundar J

    2001-01-01

    Muutuvas ühiskonnas vajatakse arenguga kaasa minemiseks traditsioonilist kapitali, inimkapitali ja sotsiaalset kapitali. Autorid uurisid Baltikumi ärikoolide õpilaste väärtusorientatsiooni, vaadeldakse Jane Jacobsi teoreetilist lähenemist

  13. Discovering reality: feminist perspectives on epistemology, metaphysics, methodology, and philosophy of science

    National Research Council Canada - National Science Library

    Harding, Sandra G; Hintikka, Merrill B

    1983-01-01

    ... FOX KELLER / Gender and Science EVELYN FOX KELLER AND CHRISTINE R. GRONTKOWSKI / The Mind's Eye NAOMI SCHEMAN / Individualism and the Objects of Psychology JANE FLAX / Political Philosophy and the Pa...

  14. 76 FR 11494 - List of Recipients of Indian Health Scholarships Under the Indian Health Scholarship Program

    Science.gov (United States)

    2011-03-02

    ... Collins, Sara Jane, University of Oklahoma, Cherokee Nation, Oklahoma Cook, David D., Rocky Vista... University, Oglala Sioux Tribe of the Pine Ridge Reservation, South Dakota Jim, Leroy, The Fielding Institute...

  15. Anàlisi teòrica dels antecedents i conseqüències de la identificació de l'alumnat amb la universitat i de la seva percepció de qualitat universitària

    Directory of Open Access Journals (Sweden)

    Irene Trullas

    2011-04-01

    Full Text Available Objecte: L'objectiu d’aquest article és desenvolupar un model conceptual centrat en els antecedents de la identificació de l'alumnat amb la universitat i la seva percepció de la qualitat universitària, perquè investigacions futures puguin provar des d’un punt de vista empíric les proposicions assenyalades.Disseny/metodologia: La metodologia consisteix en una anàlisi de la literatura empírica existent i del models teòrics actuals enfocats en el màrqueting a nivell universitari. Resultats: La identificació de l’estudiant amb la universitat i la seva percepció de qualitat de la institució són dos variables claus per a la captació i la retenció de l’alumnat. Aquest article proposa que la identificació depèn del suport institucional percebut per l'estudiant, que al seu torn està positivament relacionat amb: la comunicació corporativa, la relació universitat-alumne i la relació alumne-alumne. D’altra banda, l’ocupabilitat d’una institució educativa és relaciona positivament amb la percepció de qualitat universitària per part de l’estudiant i aquesta percepció ve determinada per la bona reputació de la universitat i per la percepció de l’estudiant que la universitat fomenta l’ocupabilitat en la seva formació. Limitacions: El model presentat es fonamenta des d’un punt de vista teòric i per tant és un punt de partida de línies futures de caràcter empíric.Implicacions pràctiques: Aquest article teòric pretén donar un punt de sortida i nou enfocament al màrqueting universitari. Esperem que aquest article ajudi a accelerar el progrés en l’àmbit del màrqueting universitari, posant de relleu qüestions fonamentals que necessiten investigació futura.Implicacions socials: La confirmació del model conceptual donaria les eines necessàries perquè les universitats desenvolupin les seves estratègies de captació i retenció d'estudiants basant-se en el màrqueting i en la segmentació, fet que

  16. Desafios na era pós genômica para o desenvolvimento de testes laboratoriais para o diagnóstico da hanseníase Challenges in the post genomic era for the development of tests for leprosy diagnosis

    Directory of Open Access Journals (Sweden)

    Mariane Martins de Araújo Stefani

    2008-01-01

    Full Text Available O diagnóstico da hanseníase se baseia em manifestações clínicas e não existe teste laboratorial para diagnosticar casos assintomáticos ou para prever progressão da doença entre indivíduos expostos. Novas análises genômicas comparativas in silico e ferramentas de biologia molecular têm sido empregadas para revelar proteínas exclusivas do Mycobacterium leprae que apresentem potencial aplicação diagnóstica. A hanseníase tuberculóide paucibacilar (PB apresenta baixo nível de anticorpos e forte resposta imune celular (RIC tipo Th1/interferon gamma (IFN-γ. A doença lepromatosa multibacilar (MB apresenta sorologia positiva e fraca RIC. Portanto, testes laboratoriais para diagnosticar hanseníase PB e MB devem contemplar testes de RIC e sorologia. Proteínas recombinantes do Mycobacterium leprae sorologicamente reativas podem ser incorporadas ao antígeno PGLI para melhorar o diagnóstico sorológico de pacientes MB. Proteínas recombinantes e peptídeos sintéticos do Mycobacterium leprae têm sido testados em ensaios de RIC/IFN-γ para diagnosticar casos PB. Sorologia anti-PGLI modificada incorporando novos antígenos do Mycobacterium leprae e ensaios baseados na RIC/produção de IFN-γ devem permitir a detecção precoce de casos MB e PB em países endêmicos.Leprosy diagnosis is based mainly on clinical manifestations and no laboratory test is available to diagnose asymptomatic disease or to predict disease progression among exposed individuals. Novel comparative genomic in silico analyses and molecular biology tools have discovered unique Mycobacterium leprae proteins with potential diagnostic application. Tuberculoid paucibacillary leprosy (PB shows low antibodies titers and strong Th1 type/ IFN-γ specific cell mediated immunity (CMI, while lepromatous multibacillary patients (MB show high antibody titers and low CMI. Therefore, laboratory tests for PB and MB leprosy diagnosis will require CMI and antibody based assays

  17. Waste to biodiesel: A preliminary assessment for Saudi Arabia.

    Science.gov (United States)

    Rehan, M; Gardy, J; Demirbas, A; Rashid, U; Budzianowski, W M; Pant, Deepak; Nizami, A S

    2018-02-01

    This study presents a preliminary assessment of biodiesel production from waste sources available in the Kingdom of Saudi Arabia (KSA) for energy generation and solution for waste disposal issues. A case study was developed under three different scenarios: (S1) KSA population only in 2017, (S2) KSA population and pilgrims in 2017, and (S3) KSA population and pilgrims by 2030 using the fat fraction of the municipal solid waste. It was estimated that S1, S2, and S3 scenarios could produce around 1.08, 1.10 and 1.41 million tons of biodiesel with the energy potential of 43423, 43949 and 56493 TJ respectively. Furthermore, annual savings of US $55.89, 56.56 and 72.71 million can be generated from landfill diversion of food waste and added to the country's economy. However, there are challenges in commercialization of waste to biodiesel facilities in KSA, including waste collection and separation, impurities, reactor design and biodiesel quality. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. L’imagination apprivoisée : représentation et factualité dans la connaissance historique

    Directory of Open Access Journals (Sweden)

    Pier Luigi Lecis

    2017-12-01

    Full Text Available This paper aims to show how Ricœur’s inquiry on memory, trace, and testimony contributes to rebalance a framework that, at the level of the dialectic between imagination and representation, would essentially present Historian’s work as a hermeneutical work. In Ricœur’s later writings, we find a differently balanced perspective by focusing the (neurobiological and psychological substrate of representation behind trace and memory. Representation precedes interpretation. And neither the fidelity of memory nor the epistemic truth of history belong to a game that would be solely played within the communicative space of a plurality of cognitive agents who are exchanging, controlling, and sharing their own experiences. Consequently, the reality of the past itself reemerges as the corollary of the practice of memory.

  19. Communication, Translation and the Global Community of Persons

    Directory of Open Access Journals (Sweden)

    Dries Deweer

    2015-07-01

    Full Text Available Paul Ricœur shared Emmanuel Mounier’s personalist and communitarian ideal of a universal community, which ensures that every human being has access to the conditions for self-development as a person. Whereas Mounier talks about communication as the structure of personhood that summons us towards the gradual enlargement of the community, Ricœur’s reflections on translation provide a missing link by referring, not just to the human capacity to communicate, but more specifically, to our capacity to translate and the implied ethics of linguistic hospitality. This allowed him to show that what enables us to enlarge the circle of brotherhood is the capacity to gradually settle in the world of the other and to welcome the other into one’s own world.

  20. Superresolution and Fluorescence Dynamics Evidence Reveal That Intact Liposomes Do Not Cross the Human Skin Barrier

    DEFF Research Database (Denmark)

    Dreier, Jes; Sørensen, Jens A; Brewer, Jonathan R

    2016-01-01

    In this study we use the combination of super resolution optical microscopy and raster image correlation spectroscopy (RICS) to study the mechanism of action of liposomes as transdermal drug delivery systems in human skin. Two different compositions of liposomes were applied to newly excised human...... skin, a POPC liposome and a more flexible liposome containing the surfactant sodium cholate. Stimulated emission depletion microscopy (STED) images of intact skin and cryo-sections of skin treated with labeled liposomes were recorded displaying an optical resolution low enough to resolve the 100 nm...... liposomes in the skin. The images revealed that virtually none of the liposomes remained intact beneath the skin surface. RICS two color cross correlation diffusion measurements of double labeled liposomes confirmed these observations. Our results suggest that the liposomes do not act as carriers...

  1. Augustitantsud kanade ja põtradega / Kairi Prints

    Index Scriptorium Estoniae

    Prints, Kairi

    2008-01-01

    21.-23. aug. Tallinna Kanuti Gildi saalis toimunud Augusti tantsufestivali lavastustest - Sonia G̤mezi "Mi madre y yo', Frédéric Giesi "Dance (Practicable), Tatjana Gordejeva "Gallina Aquatica", Iguan Dance Theatre tantsulavastus "Radiodance"

  2. Young Adult Books.

    Science.gov (United States)

    Epstein, Connie C.

    1987-01-01

    Considers the similarities between science fiction writing and young adult literature, and points out that several well-known authors, such as Robert Heinlein and Jane Yolen, write in both genres. (NKA)

  3. Inglased loovad sidet / Kreg¡A-Kristring

    Index Scriptorium Estoniae

    Kreg A-Kristring, pseud., 1962-

    1999-01-01

    Inglise juveliiride Norman Cherry, Maria Hansoni, Jivan Astfalcki, Terry Hunti ja Jane Adami kaasaegse ehtekunsti näitus "Loomas sidet" 11.V-5.VI galeriis "Sammas". Väljapanek esindab Birminghami koolkonda.

  4. Austen's "Pride and Prejudice": Comic Vision and the Teaching of Critical Thinking.

    Science.gov (United States)

    Raymond, Richard C.

    1992-01-01

    Discusses the teachable qualities of Jane Austen's novel "Pride and Prejudice." Examines the vigorous diction, plausible characterization, and comic vision that make the novel so effective in stimulating students' thought. (SR)

  5. Popmuusika / Valner Valme

    Index Scriptorium Estoniae

    Valme, Valner, 1970-

    2006-01-01

    Uutest heliplaatidest Jane's Addiction "Up From The Catacombs", Black Label Society "Shot To Hell", Evanescence "The Open Door", Ludacris "Release Therapy", Lionel Richie "Coming Home", "Freerange Records", Ojos De Brujo "Techari"

  6. Airwaves and Microblogs: A Statistical Analysis of Al-Shabaab’s Propaganda Effectiveness

    Science.gov (United States)

    2014-12-01

    manifests itself through conflicts between belligerents’ power, resolve, and trustworthiness . This is combined with the need of a terrorist group to...commenting on Eid festivals and praying for martyrs.80 Heightened messaging during religious celebrations is also displayed with al-Shabaab praising pilgrims...during the Eid- al Adha celebrations in Mecca in October 2012.81 75 Open Source Center

  7. prevalence of methicillin-resistant staphylococcus aureus in saudi ...

    African Journals Online (AJOL)

    boaz

    hot spot for the collection of MRSA because up to 6 million of their populations are expatriates from many countries. In addition, KSA hosts about four million. Muslim pilgrims from all over the world (7). KSA studies in the early 1990s consistently found low. MRSA prevalence (5% and 7.5%) which increased dramatically up to ...

  8. directives as contained in the Qur'anic phraseًﻼﯿِ ﺒَﺳ ِﮫْﯿَﻟِ إ َعﺎَﻄَﺘْﺳا ِ ﻦَ ﻣ

    African Journals Online (AJOL)

    mr tomir

    Ilorin Journal of Religious Studies, (IJOURELS). Vol.3 No.1, 2013, Pp.1-17 ... of reckless spending of public funds on the number of sponsored pilgrims, ... Istitacah and make inquiry in to government sponsorship of hajj in Nigeria at the expense of her ... cases, are conditional before the free hajj ticket is awarded. Those who ...

  9. The Dutch Are Missing in the American Curriculum

    Science.gov (United States)

    Claunch, Ann

    2009-01-01

    The Dutch are missing in any U.S. history textbook, in the content standards, and in the nationally endorsed curriculum. Outside of New York State history classes, there is almost no mention of the Dutch influence in early 17th-century America. Fleeting references to the Netherlands as a staging area for the Pilgrims' famous "Mayflower"…

  10. Signature of a Collaboration agreement between Unitar & CERN.

    CERN Multimedia

    Pierre Gildemyn

    2012-01-01

    Signature of agreement with Mr Carlos Lopes (UNITAR) and Prof Rolf Heuer (CERN). From left to right : Einar Bjorgo, Francesco Pisano, Calors Lopes, Rolf Heuer, Maurizio Bona, Frédéric Hemmer, Olivier Van Damme

  11. Plaadid / Mart Normet

    Index Scriptorium Estoniae

    Normet, Mart, 1979-

    2005-01-01

    Uutest heliplaatidest The White Stripes "Get Behind Me Satan", Coldplay "X&Y", Oasis "Don't Believe The Truth", Jane Birkin "Rendez-vous", Ocean Colour Scene "A Hyperactive Workout For The Flying Squad"

  12. Prune Belly Syndrome

    African Journals Online (AJOL)

    User

    dramnios are detected is increasingly becoming the norm. However, in resource ... ric ultrasound scan (USG) in the second trimester ... HBsAg, G6PD, retroviral screen and VDRL) was ... stalsis. The baby had normal external male genitalia.

  13. 75 FR 53667 - Space Coast Regional Innovation Cluster Competition

    Science.gov (United States)

    2010-09-01

    ... Coast Regional Innovation Cluster Competition AGENCY: Economic Development Administration (EDA... upcoming availability of funding for the Space Coast Regional Innovation Cluster (RIC) Competition under... economic development initiatives aligned with regional cluster and competitiveness analyses to sustain the...

  14. Allogeneic cellular immunotherapy for chronic B-cell leukemia

    NARCIS (Netherlands)

    Hoogendoorn, Mels

    2007-01-01

    Allogeneic stem cell transplantation (SCT) following reduced-intensity conditioning (RIC) as treatment modality has curative potential in patients suffering from chronic lymphocytic leukemia (CLL) or mantle cell lymphoma (MCL), illustrating susceptibility of these leukemic cells for the

  15. ORIGINAL ARTICLE

    African Journals Online (AJOL)

    User

    naire was administered to optometrists attending the 37th annual general meeting of the Nigerian Optomet- ric Association. ..... new cases of blindness yearly in the United States. (CDC ... estimates and general information on dia- betes and ...

  16. 76 FR 54238 - Center for Scientific Review; Notice of Closed Meeting

    Science.gov (United States)

    2011-08-31

    ...: Language, Communication, Cognition and Perception. Date: September 13-14, 2011. Time: 10 a.m. to 8 p.m... Drive, Bethesda, MD 20892 (Virtual Meeting). Contact Person: Jane A Doussard-Roosevelt, PhD, Scientific...

  17. Foot-pilgrims and backpackers: contemporary ways of travelling

    Directory of Open Access Journals (Sweden)

    Tommi Mendel

    2010-01-01

    Full Text Available This article deals with two modern forms of travelling, which both have developed into boom industries over the last 25 years: the foot pilgrimage along the Camino Francés to Santiago de Compostela in Spain and journeys along so called backpacker’s trails. Whereas the label of ‘pilgrim’ is still mostly associated with devotional persons leaving home out of purely religious motives, young people taking to the road as ‘backpackers’ are generally perceived as pleasure seeking globetrotters. However, the intention of this essay is to break with these stereotypes and to work out some of the major similarities between what at first glance appear as two entirely different ways of travelling. Within this long lasting travelling process the exterior journey always correlates with the inner journey. At the same time, a personal transformation of the protagonists is very possible to occur, be it an increase in self-confidence or an enhancement in status, prestige and identity, alongside further personal insights. Whilst travelling can therefore be seen as a form of a transition, in contrast to traditional rites de passage there is neither a fixed starting point nor a determined ending point, moreover the transformation is self-imposed and occurs on an individual than on a social level. In this context a foot-pilgrimage and a backpacker’s trip can be understood as an ideal way to evade the daily routine and the societal pressure in order to look for a different kind of living. But it may also be a personal quest for a change or an improvement of one’s situation as well as an alternative to the established social and religious institutions.

  18. Pilgrims to the Eurozone: how far, how fast?

    Czech Academy of Sciences Publication Activity Database

    Kočenda, Evžen; Kutan, A. M.; Yigit, T. M.

    2006-01-01

    Roč. 30, č. 4 (2006), s. 311-327 ISSN 0939-3625 Institutional research plan: CEZ:MSM0021620846 Keywords : real and nominal convergence * European Union * integration Subject RIV: AH - Economics http://dx.doi.org/10.1016/j.ecosys.2006.07.003

  19. Outcomes of allogeneic stem cell transplantation in patients with paroxysmal nocturnal hemoglobinuria with or without aplastic anemia.

    Science.gov (United States)

    Lee, Sung-Eun; Park, Sung Soo; Jeon, Young-Woo; Yoon, Jae-Ho; Cho, Byung-Sik; Eom, Ki-Sung; Kim, Yoo-Jin; Lee, Seok; Min, Chang-Ki; Kim, Hee-Je; Cho, Seok-Goo; Kim, Dong-Wook; Min, Woo-Sung; Lee, Jong Wook

    2017-10-01

    The aim of this study was to evaluate the long-term outcomes of allogeneic stem cell transplantation (SCT) in patients with paroxysmal nocturnal hemoglobinuria (PNH) with or without aplastic anemia (AA). A total of 33 patients with PNH clones who underwent allogeneic SCT were analyzed. After a median follow-up of 57 months (range, 6.0-151.3), the 5-year estimated overall survival rate was 87.9±5.7%. Four patients died of transplant-related mortality (TRM). With the exception of one patient with early TRM, 32 patients were engrafted. Two patients who had developed delayed GF received a second transplant and recovered. The cumulative incidences of acute graft-vs-host disease (GVHD) (≥grade II) and chronic GVHD (≥moderate) were 27.3±7.9% and 18.7±7.0%, respectively. Twenty-one patients receiving SCT with reduced-intensity conditioning (RIC) had available follow-up data for PNH cell population for the first 6 months post-transplant. Analysis of these data revealed that the PNH clones disappeared within approximately 2 months. RIC regimen was sufficient to eradicate PNH clones with sustained donor-type engraftment after allogeneic SCT. Therefore, application of allogeneic SCT with RIC should be considered in patients with PNH, in accordance with the severity of the underlying bone marrow failure. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  20. TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans.

    Science.gov (United States)

    Hannemann, Mandy; Sasidharan, Nikhil; Hegermann, Jan; Kutscher, Lena M; Koenig, Sabine; Eimer, Stefan

    2012-01-01

    Dense core vesicles (DCVs) are thought to be generated at the late Golgi apparatus as immature DCVs, which subsequently undergo a maturation process through clathrin-mediated membrane remodeling events. This maturation process is required for efficient processing of neuropeptides within DCVs and for removal of factors that would otherwise interfere with DCV release. Previously, we have shown that the GTPase, RAB-2, and its effector, RIC-19, are involved in DCV maturation in Caenorhabditis elegans motoneurons. In rab-2 mutants, specific cargo is lost from maturing DCVs and missorted into the endosomal/lysosomal degradation route. Cargo loss could be prevented by blocking endosomal delivery. This suggests that RAB-2 is involved in retention of DCV components during the sorting process at the Golgi-endosomal interface. To understand how RAB-2 activity is regulated at the Golgi, we screened for RAB-2-specific GTPase activating proteins (GAPs). We identified a potential RAB-2 GAP, TBC-8, which is exclusively expressed in neurons and which, when depleted, shows similar DCV maturation defects as rab-2 mutants. We could demonstrate that RAB-2 binds to its putative GAP, TBC-8. Interestingly, TBC-8 also binds to the RAB-2 effector, RIC-19. This interaction appears to be conserved as TBC-8 also interacted with the human ortholog of RIC-19, ICA69. Therefore, we propose that a dynamic ON/OFF cycling of RAB-2 at the Golgi induced by the GAP/effector complex is required for proper DCV maturation.

  1. Reduced intensity conditioning is superior to nonmyeloablative conditioning for older chronic myelogenous leukemia patients undergoing hematopoietic cell transplant during the tyrosine kinase inhibitor era

    DEFF Research Database (Denmark)

    Warlick, Erica; Ahn, Kwang Woo; Pedersen, Tanya L

    2012-01-01

    Tyrosine kinase inhibitors (TKIs) and reduced intensity conditioning (RIC)/nonmyeloablative (NMA) conditioning hematopoietic cell transplants (HCTs) have changed the therapeutic strategy for chronic myelogenous leukemia (CML) patients. We analyzed post-HCT outcomes of 306 CML patients reported to...

  2. Weight and psychiatry

    African Journals Online (AJOL)

    Adele

    Beyond the physical aspects of weight, the psychological mean- ing sees the virtues of ... sion in the development and persistence of adolescent obesity. Pediat- rics 2002 ... or secondary as in mood, anxiety or psychotic disorders. II. a related.

  3. Untitled

    African Journals Online (AJOL)

    objective of this study was to determine the type and amount of solid wastes generated and to assess the ... ric pathogens by providing feeding stock and favorable environment. Ground and ..... WHO, News letter on Environmental. Health, No ...

  4. The bioethics of cosmetic psychopharmacology

    African Journals Online (AJOL)

    Adele

    ric disorders, but also for sub-clinical symptoms, and on the possible ... major advance in psychiatry, that they suffer from depression ... The language we use in discussing scientific and medical .... can Journal of Psychiatry 155, 373-379. 1998.

  5. Spatiotemporal visualization of subcellular dynamics of carbon nanotubes

    KAUST Repository

    Serag, Maged F.; Braeckmans, Kevin; Habuchi, Satoshi; Kaji, Noritada; Bianco, Alberto; Baba, Yoshinobu

    2012-01-01

    throughout the plant cell. By using raster scan image correlation spectroscopy (RICS), we were able to generate highly quantitative spatial maps of CNTs diffusion in different cell compartments. The spatial map of diffusion values revealed that the uptake

  6. Download this PDF file

    African Journals Online (AJOL)

    abel

    imperial networks – multi-directional web-like systems that existed between the ... For example, the heads of the LMP and RIC both reported directly to Cabinet officials ... England, selection committees preferred to hire military officers as chief ...

  7. Redhaus Piiteris

    Index Scriptorium Estoniae

    2009-01-01

    Kunstnike rühmitus Redhaus (Piret Peil, Kalle Aasamäe, Jane Remm) osaleb projektiga "Kangelased ja kaunitarid" 24. oktoobrist 8. novembrini Peterburis toimuval rahvusvahelisel näitusel "Sea level" Maneeži galeriis

  8. Pop / Aleksander T. Yostafa

    Index Scriptorium Estoniae

    Yostafa, Aleksander T.

    2006-01-01

    Heliplaatidest: t.A.T.u "The Best", Level 42 "Retroglide", Robbie Williams "Rudebox", Jane's Addiction "Up From The Catacombs" (The Best Of), Erase Errata "Nightlife", Sting "Songs from The Labyrinth", The Lemonheads "The Lemonheads"

  9. Adhesion defective BHK cell mutant has cell surface heparan sulfate proteoglycan of altered properties

    DEFF Research Database (Denmark)

    Couchman, J R; Austria, R; Woods, A

    1988-01-01

    In the light of accumulating data that implicate cell surface heparan sulfate proteoglycans (HSPGs) with a role in cell interactions with extracellular matrix molecules such as fibronectin, we have compared the properties of these molecules in wild-type BHK cells and an adhesion-defective ricin......-resistant mutant (RicR14). Our results showed that the mutant, unlike BHK cells, cannot form focal adhesions when adherent to planar substrates in the presence of serum. Furthermore, while both cell lines possess similar amounts of cell surface HSPG with hydrophobic properties, that of RicR14 cells had decreased...... sulfation, reduced affinity for fibronectin and decreased half-life on the cell surface when compared to the normal counterpart. Our conclusions based on this data are that these altered properties may, in part, account for the adhesion defect in the ricin-resistant mutant. Whether this results from...

  10. Literature and cinema: images of femininity in pride and prejudice Literature and cinema: images of femininity in pride and prejudice

    Directory of Open Access Journals (Sweden)

    Sandra Guardini T. Vasconcelos

    2008-04-01

    Full Text Available By comparing the novel Pride and Prejudice by Jane Austen with an American filmic version from 1940, the article draws attention to the shift in the focus of the two narratives. While the novel provides alternative possibilities for the stories of the female characters, the filmic version chooses to reinforce an idealized image of social harmony. Ao comparar o romance Pride and Prejudice de Jane Austen com uma versão fílmica americana de 1940, o artigo chama atenção para a mudança de enfoque das duas narrativas. Enquanto o romance fornece possibilidades alternativas para as estórias das personagens femininas, a versão fílmica opta por reforçar uma imagem idealizada de harmonia social.

  11. The 5T mouse multiple myeloma model: Absence of c-myc oncogene rearrangement in early transplant generations

    NARCIS (Netherlands)

    Radl, J.; Punt, Y.A.; Enden-Vieveen, M.H.M. van den; Bentvelzen, P.A.J.; Bakkus, M.H.C.; Akker T., W. van den; Benner, R.

    1990-01-01

    Consistent chromosomal translocations involving the c-myc cellular oncogene and one of the three immunoglobulin loci are typical for human Burkitt's lymphoma, induced mouse plasmacytoma (MPC) and spontaneously arising rat immunocytoma (RIC). Another plasma cell malignancy, multiple myeloma (MM),

  12. 75 FR 63147 - Solicitation of Applications for the Public Works, Economic Adjustment Assistance, and Global...

    Science.gov (United States)

    2010-10-14

    ... development of regional innovation clusters (RICs), which are broadly defined as geographic concentrations of... submit paper submissions to: Economic Development Administration, Atlanta Regional Office, 401 West... Development Administration, Austin Regional Office, 504 Lavaca, Suite 1100, Austin, Texas 78701- 2858...

  13. Impact of postremission consolidation chemotherapy on outcome after reduced-intensity conditioning allogeneic stem cell transplantation for patients with acute myeloid leukemia in first complete remission

    DEFF Research Database (Denmark)

    Yeshurun, Moshe; Labopin, Myriam; Blaise, Didier

    2014-01-01

    The objective of the current study was to investigate the role of postremission consolidation chemotherapy before reduced-intensity conditioning (RIC) allogeneic stem cell transplantation (alloSCT) for patients with acute myeloid leukemia (AML) in first complete remission (CR1)....

  14. Kinematograafiline rätsepakunst / Jaan Ruus

    Index Scriptorium Estoniae

    Ruus, Jaan, 1938-2017

    2007-01-01

    Taivani päritolu režissöör Ang Lee tema mängufilm "Mõistus ja tunded" ("Sense and Sensibility") : stsenarist Jane Austeni romaani põhjal Emma Thompson : Suurbritannia - Ameerika Ühendriigid 2005

  15. 1. IV avati Tallinna Kunstihoone galeriis šoti videokunstinäitus "Nähtamatud väljad"

    Index Scriptorium Estoniae

    2004-01-01

    Kuraatorid Sarah Felton ja Su Grierson, osalevad kunstnikud Victoria Clare Bernie, Samantha Clark, Maria Doyle, S. Felton, S. Grierson, Belinda Guidi, Anne Bjerge Hansen, Metacorpus, Jane McInally, Rosalind Nashashibi, Susannah Silver ja Susan Sloan

  16. 77 FR 72873 - Notice of Revocation of Customs Broker Licenses

    Science.gov (United States)

    2012-12-06

    ... 17091 New York. Levine Seth A 09759 New York. Walsh John X 03979 New York. Palmieri Eugene D 02632 New.... Galik Jane M 10357 Philadelphia. D'Amico Lenore Anne 15093 Philadelphia. Frederick Ted D 10654...

  17. Kunsti tõmbavad vaatama p-tähed : uus näitus lastekunstikooli galeriis / Raimu Hanson

    Index Scriptorium Estoniae

    Hanson, Raimu, 1957-

    2008-01-01

    Näitus "P... ja p... kunst" Tartu Lastekunstikooli galeriis, kuraator Margus Kiis. Oma töid eksponeerivad Rauno Thomas Moss, Enn Tegova, Maris Palgi, Jane Remm, Kristiina Viin, Martin Vaher, Kaspar Jassa, Mariliin Kindsiko jt.

  18. Transition from Terrorist Event Management to Consequence Management, Executive Summary

    Science.gov (United States)

    1982-03-31

    hUMIEe " BDM/W-82-l1 5-TR AUTO11(o 1. CONTR ACT OR GRANT NumURe) J. C. Evanis, M. K. Pilgrim, C. J. Potter EMW-C-0744 9. PER•O^•ING ORGANIZATIN NAME...should, and is expected to, provide leadership in this regard. There exists a variety of experience and planning for responding to terrorist events. The

  19. Influence of long-term treatment with glyceryl trinitrate on remote ischemic conditioning

    DEFF Research Database (Denmark)

    Hauerslev, Marie; Mørk, Sivagowry Rasalingam; Pryds, Kasper

    2018-01-01

    Remote ischemic conditioning (RIC) protects against sustained myocardial ischemia. Due to overlapping mechanisms this protection may be altered by glyceryl trinitrate (GTN), which is commonly used in the treatment of patients with chronic ischemic heart disease. We investigated whether long-term ...

  20. 76 FR 21700 - Notice of Request for Extension and Revision of a Currently Approved Collection

    Science.gov (United States)

    2011-04-18

    ..., Science and Technology, Agricultural Marketing Service, U.S. Department of Agriculture, 1400 Independence... may be sent to Jane Ho, Technical Services Branch, Science and Technology, Agricultural Marketing... / Monday, April 18, 2011 / Notices#0;#0; [[Page 21700

  1. Tips for Teens: The Truth about Marijuana

    Science.gov (United States)

    ... Mary Jane, Blunt, Joint, Trees Get the Facts… Marijuana affects your brain. THC (the active ingredient in marijuana) affects the nerve cells in the part of the brain where memories are formed. Marijuana affects your self- ...

  2. Home market is too small for Laima / Uva Seglina

    Index Scriptorium Estoniae

    Seglina, Uva

    2004-01-01

    Läti magusatootja Laima turundusjuht ettevõtte tegevusest, eesmärkidest Baltimaade turul, turundusstrateegiast ning olulisematest turundusalastest saavutustest, Laima brändi tugevatest ja nõrkadest. Kommenteerivad Andra Treibaha, Eriks Stenzenieks, Jane Ounaste ja Edgars Skulte

  3. 26. III avati Tartu Y-galerii E-saalis...

    Index Scriptorium Estoniae

    2004-01-01

    MTÜ loovkeskuse ja Anne noortekeskuse multimeedialabori interdistsiplinaarse Art-Merge õpikoja näitus. 20.-26. III toimunud õpikoja tegevuskunsti osa juhtis inglise kunstnik Natalie Waldbaum, multimeedia sektorit Jane Remm, kaasaegse tantsu ja teatri osa Kaia Kapsta

  4. Brief Introduction to Hepatitis B for Parents of Adopted Children

    Science.gov (United States)

    Brief Introduction to Hepatitis B for Parents of Adopted Children by Sarah Jane Schwarzenberg, MD What is hepatitis B? ... injury will also need careful medical management. In short, prospective par- ents of children with hepatitis B ...

  5. Naisteromaanide uimarohi / Ilona Martson, Kristi Pärn

    Index Scriptorium Estoniae

    Martson, Ilona, 1970-

    1997-01-01

    Atwood, Margaret. Röövelpruut; Austen, Jane. Veenmine; Sheldon, Sidney. Veresidemed; Ondaatje, Michael. Inglise patsient; Lind, Hera. Kahe mehe vahel; Simmel, Johannes Mario. Vastust teab vaid tuul; Gaskin, Catherine. Fiona; Gaskin, Catherine. Perekonnaasjad; Barne, John. Evita

  6. 20 aastat Berliini meediakunsti festivali / Jane Suviste

    Index Scriptorium Estoniae

    Suviste, Jane

    2008-01-01

    Rahvusvaheline meediakunsti festival "Transmediale 2008" Berliinis 29. I-3. II ja näitus 29. I-24. II. Näitusest "Conspire / Salanõu" (kuraator Natasha Petreshin Bachelez), konverentsist, kolme Janez Jansha pseudonüümiga sloveeni kunstniku probleeme tekitanud performance'ist "Signature. Event. Context" jm. Peaauhind läks Julia Meltzeri ja David Thorne'i videole "Not a Matter of If but When"

  7. Lahinguväljalt ärikooli / Jane Porter

    Index Scriptorium Estoniae

    Porter, Jane

    2008-01-01

    Ameerikas tsiviilellu naasnud sõjaväelaste üha populaarsemaks muutunud otsusest asuda õppima ärikoolidesse. Sõjaväelise taustaga õppuritest on huvitatud ka nii ärikoolid kui ettevõtted, kuna nad on distsiplineeritud ja omavad juhtimiskogemust

  8. Kuidas suunata noori loodusest hoolima? / Jane Adler

    Index Scriptorium Estoniae

    Adler, Jane

    2008-01-01

    Kuusalu keskkoolis toimunud ökotantsufestivalist. Kolm peapreemiat anti välja parimatele looduse jäljendajatele: Keila lasteaiale "Vikerkaar" kava "Linnud ja meri" eest, Petsi spordiklubile (1.-3. klass) kava "Kärbeste ralli" eest ning Kunda ühisgümnaasiumile (10.-12. klass) kava "Elu" eest

  9. Jane: A Case Study in Anorexia Nervosa.

    Science.gov (United States)

    Willingham, Barbara

    1988-01-01

    The article reports the case history of a 15-year-old Australian girl with anorexia nervosa. Information is also given on prevalence, causes, definitions, and treatments including hospitalization, co-therapy, psychotherapy, behavior modification, family therapy, and counseling. (DB)

  10. Abielluda! Abielluda! Abielluda! / Jaan Ruus

    Index Scriptorium Estoniae

    Ruus, Jaan, 1938-2017

    2008-01-01

    Lühiarvustus Jane Austeni romaani ekraniseeringule "Mõistus ja tunded" ("Sens and Sensibility") : stsenarist Emma Thompson : režissöör Ang Lee : Suurbritannia - Ameerika Ühendriigid 1995. Lisatud andmed režissööri kohta

  11. The National Institutes of Health Clinical Center

    Science.gov (United States)

    ... a rare disease not typically found in children — Cushing's Syndrome. Her adrenal glands produced too much of the ... Jane did a school science fair project on Cushing's Syndrome. She also wrote a book so that other ...

  12. Ökoloogia ja keskkonnateaduste doktorikool : täitus aasta projekti käivitumisest TLÜs / Tiiu Koff

    Index Scriptorium Estoniae

    Koff, Tiiu, 1955-

    2006-01-01

    Koostöös Ökoloogia ja keskkonnateaduste doktorikooliga toimusid Tallinna Ülikoolis Exeteri Ülikooli professor Christopher J. Caseldine ja Hulli Ülikooli lektor Jane Buntingi loengud ning Post-POLLANDCAL teadusvõrgustiku seminar Ökoloogia Instituudis

  13. Theology of Karman: merit, death and release in the case of Varanasi, India

    Directory of Open Access Journals (Sweden)

    Erik Reenberg Sand

    2010-01-01

    Full Text Available In this article, the focus is on the question as to what motives the pilgrims may have for performing pilgrimage, and, in doing this, the author deals especially with the Hindu tradition, namely with pilgrimage to Varanasi, Banaras or Kāśī, which is often considered the Hindu sacred city par excellence by both Hindus and Westerners alike.The sacred power of Varanasi has three sources: the eternal presence of Śiva from the time of creation, the cremation ghāṭand the presence of the river Gaṅgā. Furthermore, we found that the most characteristic thing about the power of Varanasi is its connection with death and its power to confer on the pilgrim the fruit of complete release from the circle of birth, death, and rebirth, something which is normally the privilege of the adherents of ascetic and other non-worldly systems. This feature is still reflected in the fact that many elderly people come to Varanasi in order to die and get cremated here, and many people from the surrounding areas still take the bodies of their dead relatives to Varanasi for cremation.

  14. Barriers and motivations affecting Information Systems usage by Hajj–Umrah religious tourism operators in Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Hani Brdesee

    2013-03-01

    Full Text Available Hajj & Umrah religious tourism accounts for seven million visitors each year in Saudi Arabia. The government has recently taken initiatives to promote the use of Information Systems (IS in the religious tourism industry, encouraging firms to adopt IS innovations like e-commerce and enforcing the use of the Makha’a information system in Umrah for external pilgrims and the Yosr information system in Hajj for internal pilgrims. This study outlines the motivations and challenges that affect the utilisation of various IS services in the Saudi religious tourism industry through a qualitative analysis of the views and perceptions of senior executives and owners of travel firms. The findings suggest that while government initiatives and industry competitiveness were two positive factors promoting IS use, there are some major barriers preventing private firms from fully utilising the advantages of information systems. These include external factors such as lack of support from the IT industry and access to IT resources as well as internal factors within an organisation such as lack of commitment or the need for professional IT expertise. The study finds that relative advantage is a critical contributor to IS utilisation which depends on information systems characteristics.

  15. Optimization of hybrid model on hajj travel

    Science.gov (United States)

    Cahyandari, R.; Ariany, R. L.; Sukono

    2018-03-01

    Hajj travel insurance is an insurance product offered by the insurance company in preparing funds to perform the pilgrimage. This insurance product helps would-be pilgrims to set aside a fund of saving hajj with regularly, but also provides funds of profit sharing (mudharabah) and insurance protection. Scheme of insurance product fund management is largely using the hybrid model, which is the fund from would-be pilgrims will be divided into three account management, that is personal account, tabarru’, and ujrah. Scheme of hybrid model on hajj travel insurance was already discussed at the earlier paper with titled “The Hybrid Model Algorithm on Sharia Insurance”, taking the example case of Mitra Mabrur Plus product from Bumiputera company. On these advanced paper, will be made the previous optimization model design, with partition of benefit the tabarru’ account. Benefits such as compensation for 40 critical illness which initially only for participants of insurance only, on optimization is intended for participants of the insurance and his heir, also to benefit the hospital bills. Meanwhile, the benefits of death benefit is given if the participant is fixed die.

  16. A Large Solid Inner Core at Mercury

    Science.gov (United States)

    Genova, A.; Goossens, S.; Mazarico, E.; Lemoine, F. G.; Neumann, G. A.; Kuang, W.; Sabaka, T. J.; Smith, D. E.; Zuber, M. T.

    2018-05-01

    New measurements of the polar moments of inertia of the whole planet and of the outer layers (crust+mantle), and simulations of Mercury’s magnetic field dynamo suggest the presence of a solid inner core with a Ric 0.3-0.5 Roc.

  17. Identification of novel open reading frames from metagenomic libraries generated from extremophilic organisms: application of metagenomics and high throughput screening for novel enzyme isolation

    CSIR Research Space (South Africa)

    Visser, Daniel F

    2006-10-01

    Full Text Available : Olive Oil / Rhodamine B Tributyrin Fluorescence under UV Secondary Screening Colorimet- ric - PNP-ester substrates (C2, C4, C18); Substrate, Temperature and pH Profiling 16S ribosomal RNA gene (DNA level) Amidase ATP-dependant protease Beta...

  18. Värviküllane elujanu / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2004-01-01

    Suurbritannia Vähiuuringute keskusele loodud Elu Aed 2004. a. Chelsea aiandusnäitusel. Aia kujundasid Jane Hudson & Erik de Maeijer. Mosaiiktee autor Maggy Howarth. Soojades toonides külluslik lilleaed sisendab elujõudu, vabadust ja energiat. 4 ill

  19. Cannes'i filmifestivali võitis Rumeenia abordidraama / Triin Tael

    Index Scriptorium Estoniae

    Tael, Triin

    2007-01-01

    Cannes'i filmifestivalil jagati auhindu. Kuldse Palmioksa sai rumeenlase Christian Mungiu "4 kuud, 3 nädalat ja 2 päeva" ("4 Luni, 3 Saptamini Si 2 Zile"), elutöö auhinna Jane Fonda. Ka teistest auhinnatutest

  20. Cannes'i filmifestivali võitis rumeenia draama

    Index Scriptorium Estoniae

    2007-01-01

    Cannes'i filmifestivalil jagati auhindu. Kuldse Palmioksa sai rumeenlase Christian Mungiu "4 kuud, 3 nädalat ja 2 päeva" ("4 Luni, 3 Saptamini Si 2 Zile"), elutöö auhinna Jane Fonda. Ka teistest auhinnatutest