Malbaša Radomir V.
Full Text Available In human nutrition, nucleic acids have to be balanced and limited up to 2 g/day because purines are degraded to urate, and excessive production of urate is a cause of gout which primarily affects adult males. Tea fungus beverage is a well known drink with high nutritional value and certain curative effects. Its benefits have been proved in a number of studies but it is still necessary to examine some potential harmful effects of this beverage. The aim of this paper was to investigate content of ribonucleic acids (RNA produced during tea fungus fermentation on a usual substrate sweetened black tea, and on Jerusalem artichoke tubers (J.A.T extract using method by Munro and Fleck (1966. pH, ribonucleic acids and also the production of proteins that affect purity of nucleic acids preparations were monitored. A higher value of RNA has been noticed in J.A.T. beverage (0.57 mg/ml and with observation of usual daily dose of the beverage it is completely safe and useful one.
Kelmers, A. D.; Novelli, G. David; Stulberg, M. P.
Numerous experimental techniques for the separation of transfer ribonucleic acids have been successful in preparing partially purified fractions of several specific t-RNAs. Many of the existing methods have depended upon the differential solubility of specific t-RNAs in complex two-phase systems (1-6) and the separation was achieved by means of counter-current extraction techniques. Column chromatography experiments using cellulose exchangers, (7,8) methylated albumin (9,10) or with solvent phases supported on inert material (11-13) have also shown partial separation of specific t-RNAs. Paper chromatographic procedures have produced partial resolutions of t-RNA.14 Methods involving chemical treatment of specific t-RNAs have been reported (15-19).
EDSTROM, J E
Microphoretic purine-pyrimidine analyses of the ribonucleic acid (RNA) in nucleoli, nucleoplasm, cytoplasm, and yolk nuclei of spider oocytes have been carried out. The material necessary for the analyses was isolated by micromanipulation. Determinations of the amounts of RNA in the different parts of the cell were also performed. No differences between the composition of RNA in the nucleolus and the cytoplasm could be disclosed. Nucleoplasmic RNA was, on the other hand, distinctly different from that in the nucleolus and in the cytoplasm. The difference lies in the content of adenine, which is highest in nucleoplasmic RNA. The few analyses carried out on yolk nuclei showed their RNA to be variable in composition with a tendency to high purine values. The cytoplasm contains about 99 per cent of the total RNA in these cells, the nucleoplasm about 1 per cent, and the nucleolus not more than 0.3 per cent, although the highest concentrations are found in these latter structures. When considered in the light of other recent findings the results are compatible with the view that nucleolar RNA is the precursor of cytoplasmic RNA.
Friedman, Robert M.; Fantes, Karl H.; Levy, Hilton B.; Carter, William B.
Actinomycin D-treated chick fibroblasts were infected with purified 32P-labeled Semliki forest virus, and ribonucleic acid (RNA) was extracted after 1 or 2 hr. Within 1 hr, viral RNA forms sedimenting in sucrose gradients at 42S, 30S, and 16S were present. The 42S form corresponded to the RNA of the virion. The 16S form appeared to be a double-stranded template for the formation of new viral RNA, since nascent RNA was associated with it and the molecule could be heat-denatured and subsequently reannealed by slow cooling. Interferon treatment before infection, or puromycin (50 μg/ml) or cycloheximide (200 μg/ml) added at the time of virus infection, had no effect on the formation of the 30S RNA but inhibited the production of the 16S form. Several findings made it unlikely that these results were due to breakdown of parental RNA and reincorporation of 32P into progeny structures. The results suggested that the mechanism of interferon action involves inhibition of protein synthesis by parental viral RNA, since a specific viral RNA polymerase had previously been demonstrated to be necessary for production of 16S RNA. No protein synthesis appears necessary for formation of 30S RNA from parental virus RNA. PMID:5621488
Luzzati, Denise (Institut de Biologie Physico-Chimique, Paris, France). Effect of thymine starvation on messenger ribonucleic acid synthesis in Escherichia coli. J. Bacteriol. 92:1435–1446. 1966.—During the course of thymine starvation, the rate of synthesis of messenger ribonucleic acid (mRNA, the rapidly labeled fraction of the RNA which decays in the presence of dinitrophenol or which hybridizes with deoxyribonucleic acid) decreases exponentially, in parallel with the viability of the thymine-starved bacteria. The ability of cell-free extracts of starved bacteria to incorporate ribonucleoside triphosphates into RNA was determined; it was found to be inferior to that of extracts from control cells. The analysis of the properties of cell-free extracts of starved cells shows that their decreased RNA polymerase activity is the consequence of a modification of their deoxyribonucleic acid, the ability of which to serve as a template for RNA polymerase decreases during starvation. PMID:5332402
Peeters, M.; Huang, C. L.; Vonk, L. A.; Lu, Z. F.; Bank, R. A.; Helder, M. N.; Doulabi, B. Zandieh
Objectives Studies which consider the molecular mechanisms of degeneration and regeneration of cartilaginous tissues are seriously hampered by problematic ribonucleic acid (RNA) isolations due to low cell density and the dense, proteoglycan-rich extracellular matrix of cartilage. Proteoglycans tend
Peeters, M; Huang, C L; Vonk, L A; Lu, Z F; Bank, R A; Helder, M N; Doulabi, B Zandieh
OBJECTIVES: Studies which consider the molecular mechanisms of degeneration and regeneration of cartilaginous tissues are seriously hampered by problematic ribonucleic acid (RNA) isolations due to low cell density and the dense, proteoglycan-rich extracellular matrix of cartilage. Proteoglycans tend
Hamill, W.D.; Grant, D.M.; Cooper, R.B.; Harmon, S.A.
The carbon-13 nuclear magnetic resonance spectra of the 13 C-enriched C-4 uridine carbons in 5S ribosomal ribonucleic acid of Salmonella typhimurium, strain JL-1055, was obtained. The most striking feature of the 5S RNA spectrum was the large number of well-resolved lines in the uridine band covering a chemical shift range of approximately 3.6 ppM. This data was used to obtain information on the secondary structure. The number of uridines involved in secondary interactions is estimated to be at least 75% and may be as high as 95%
Rosa, M.D.; Gottlieb, E.; Lerner, M.R.; Steitz, J.A.
The nucleotide sequence of the region of the Epstein-Barr virus genome that specified two small ribonucleic acids (RNAs), EBER 1 and EBER 2, has been determined. Both of these RNAs are encoded by the right-hand 1,000 base pairs of the EcoRI J fragment of EBV deoxyribonucleic acid. EBER 1 is 166 (167) nucleotides long and EBER 2 is 172 +- 1 nucleotides long; the heterogeneity resides at the 3' termini. The EBER genes are separated by 161 base pairs and are transcribed from the same deoxyribonucleic acid strand. In vitro, both EBER genes can be transcribed by RNA polymerase III; sequences homologous to previously identified RNA polymerase III intragenic transcription control regions are present. Striking similarities are therefore apparent both between the EBERs and the two adenovirus-associated RNAs, VAI and VAII, and between the regions of the two viral genomes that specify these small RNAs. We have shown that VAII RNA as well as VAI RNA and the EBERs exist in ribonucleoprotein complexes which are precipitable by anti-La antibodies associated with systemic lupus erythematosus. Finally the authors have demonstrated that the binding of protein(s) from uninfected cells confers antigenicity on each of the four virus-encoded small RNAs.
Verkhoturov, Dmitriy S; Geng, Sheng; Verkhoturov, Stanislav V; Kim, Hansoo; Schweikert, Emile A
In this study, the authors used cluster-secondary ion mass spectrometry method to investigate the preserved transfer ribonucleic acid (tRNA) encapsulated between two free-standing graphene sheets. Single impacts of 50 keV C60 (2+) projectiles generated the emission of tRNA fragment ions in the transmission direction for mass selection and detection in a time-of-flight mass spectrometer. Ribonucleic acid (RNA) is extremely unstable and prone to rapid enzymatic degradation by ribonucleases. Employing graphene to isolate RNA from the environment, the authors prevent the aforementioned process. Encapsulation was achieved by drop casting a solution of tRNA, prepared using deuterated water, onto one graphene sheet and covering it with another. The event-by-event bombardment/detection mode allowed us to use colocalization analysis method to characterize the tRNA and its immediate environment. The authors found that upon drying, tRNA agglomerated into nanostructures ∼60 nm in diameter via formation and subsequent drying of aqua cells. The tRNA nanoagglomerates had a density of ∼42 structures per μm(2) with coverage of ∼12% of the surface area. In addition, trace amounts of water remained mostly around the tRNA nanoagglomerates, probably in the form of hydration.
Mousa, Tohamy A.; Roushdy, Hamed M.; Raid, Nahed A.; Al-Zahaby, Al-Ahmady S.; Sanad, Samia M.
Four groups of adult male albino rats were subjected to whole body gamma-irradiation at the exposure levels of 200, 400, 600 and 1000 rads and the spinal ganglia were dissected out after different intervals of 3 hr., 1, 3, 5, 7, 10, 15 and 30 days. Nissl bodies and ribonucleic acid were demonstrated histochemically. Gamma irradiation may cause a decrease in RNA synthesis which was reflected in a reduced amount of Nissl substance visible in toluidine blue stained you thick sections of spinal ganglion of gamma irradiated rats and in the total amount of cytoplasmic RNA in pyronin-methyl green stained sections compared with control animals
Lemieszek, Marta Kinga; Ribeiro, Miguel; Guichard Alves, Helena; Marques, Guilhermina; Nunes, Fernando Milheiro; Rzeski, Wojciech
Despite the large popularity of the Boletus edulis mushroom, little is known about its influence on human health and the possibilities of its therapeutic use. Nevertheless, several reports revealed the usefulness of biopolymers isolated from it in cancer treatment. Our previous studies have shown that B. edulis water soluble biopolymers are not toxic against normal colon epithelial cells (CCD841 CoTr) and at the same concentration range elicited a very prominent antiproliferative effect in colon cancer cells (LS180) which was accompanied with cell cycle arrest in the G0/G1 phase. The purpose of the present study was to verify the proapoptotic properties of a selected fraction from B. edulis - BE3, as well as determine its chemical nature. The BE3 fraction was extracted with hot water and purified by anion-exchange chromatography. Further chemical examinations revealed that BE3 consists mainly of ribonucleic acid (59.1%). The ability of BE3 to induce programmed cell death was examined in human colon cancer cell lines LS180 and HT-29 by measuring caspase activation, DNA fragmentation and expression of BAX, BCL2, TP53 and CDKN1A genes. The sensitivity of colon cancer cells with silenced BAX, TP53 and CDKN1A expression to BE3 treatment was also evaluated. We have demonstrated for the first time that the BE3 fraction is a potent apoptosis inducer in human colon cancer cells. The revealed mechanism of apoptosis triggering was dependent on the presence of functional p53 and consequently was a little different in investigated cell lines. Our results indicated that BE3 stimulated proapoptotic genes BAX (LS180, HT-29), TP53 (LS180) and CDKN1A (HT-29) while at the same time silenced the expression of the key prosurvival gene BCL2 (LS180, HT-29). The obtained results indicate the high therapeutic potential of the BE3 fraction against colon cancer, yet it is necessary to further confirm fraction efficacy and safety in animal and clinical studies.
Van den Eynde, H.; De Baere, R.; Shah, H. N.; Gharbia, S. E.; Fox, G. E.; Michalik, J.; Van de Peer, Y.; De Wachter, R.
The 5S ribosomal ribonucleic acid (rRNA) sequences were determined for Bacteroides fragilis, Bacteroides thetaiotaomicron, Bacteroides capillosus, Bacteroides veroralis, Porphyromonas gingivalis, Anaerorhabdus furcosus, Fusobacterium nucleatum, Fusobacterium mortiferum, and Fusobacterium varium. A dendrogram constructed by a clustering algorithm from these sequences, which were aligned with all other hitherto known eubacterial 5S rRNA sequences, showed differences as well as similarities with respect to results derived from 16S rRNA analyses. In the 5S rRNA dendrogram, Bacteroides clustered together with Cytophaga and Fusobacterium, as in 16S rRNA analyses. Intraphylum relationships deduced from 5S rRNAs suggested that Bacteroides is specifically related to Cytophaga rather than to Fusobacterium, as was suggested by 16S rRNA analyses. Previous taxonomic considerations concerning the genus Bacteroides, based on biochemical and physiological data, were confirmed by the 5S rRNA sequence analysis.
Peeters, M; Huang, C L; Vonk, L A; Lu, Z F; Bank, R A; Helder, M N; Doulabi, B Zandieh
Studies which consider the molecular mechanisms of degeneration and regeneration of cartilaginous tissues are seriously hampered by problematic ribonucleic acid (RNA) isolations due to low cell density and the dense, proteoglycan-rich extracellular matrix of cartilage. Proteoglycans tend to co-purify with RNA, they can absorb the full spectrum of UV light and they are potent inhibitors of polymerase chain reaction (PCR). Therefore, the objective of the present study is to compare and optimise different homogenisation methods and RNA isolation kits for an array of cartilaginous tissues. Tissue samples such as the nucleus pulposus (NP), annulus fibrosus (AF), articular cartilage (AC) and meniscus, were collected from goats and homogenised by either the MagNA Lyser or Freezer Mill. RNA of duplicate samples was subsequently isolated by either TRIzol (benchmark), or the RNeasy Lipid Tissue, RNeasy Fibrous Tissue, or Aurum Total RNA Fatty and Fibrous Tissue kits. RNA yield, purity, and integrity were determined and gene expression levels of type II collagen and aggrecan were measured by real-time PCR. No differences between the two homogenisation methods were found. RNA isolation using the RNeasy Fibrous and Lipid kits resulted in the purest RNA (A260/A280 ratio), whereas TRIzol isolations resulted in RNA that is not as pure, and show a larger difference in gene expression of duplicate samples compared with both RNeasy kits. The Aurum kit showed low reproducibility. For the extraction of high-quality RNA from cartilaginous structures, we suggest homogenisation of the samples by the MagNA Lyser. For AC, NP and AF we recommend the RNeasy Fibrous kit, whereas for the meniscus the RNeasy Lipid kit is advised.Cite this article: M. Peeters, C. L. Huang, L. A. Vonk, Z. F. Lu, R. A. Bank, M. N. Helder, B. Zandieh Doulabi. Optimisation of high-quality total ribonucleic acid isolation from cartilaginous tissues for real-time polymerase chain reaction analysis. Bone Joint Res 2016
Björk, G R; Neidhardt, F C
Matched pairs of transductant strains differing by the presence of absence of 5-methyluridine (ribothymidine) (m5U) in their transfer ribonucleic acid (tRNA) were used to study the function of this modified nucleoside in Escherichia coli. Ordinary measurements of growth rate in different media revealed no effect of the loss of m5U in tRNA. A gene located close to trmA (the structural cistron for the methyltransferase that produces m5U in tRNA), however, was found to reduce the growth rates significantly, depending on the medium and the temperature of cultivation. Measurement of codon recognition, macromolecular composition, tRNA binding to the ribosome, and the rate of protein chain elongation in vivo indicated no disadvantage caused by the lack of m5U. The regulation of ilv and his operons seemed also to be unaffected by the absence of m5U in the tRNA. In a mixed population experiment, however, cells possessing m5U in their tRNA seemed to have a distinct advantage over cells lacking this modified nucleoside. This experiment provides the first indication of the overall value of m5U in tRNA.
Sameshima, M.; Liebhaber, S.A.; Schlessinger, D.
The turnover rates of /sup 3/H-labeled 18S ribosomal ribonucleic acid (RNA), 28S ribsomal RNA, transfer RNA, and total cytoplasmic RNA were very similar in growing WI-38 diploid fibroblasts. The rate of turnover was at least twofold greater when cell growth stopped due to cell confluence, /sup 3/H irradiation, or treatment with 20 mM NaN/sub 3/ or 2 mM NaF. In contrast, the rate of total /sup 3/H-protein turnover was the same in growing and nongrowing cells. Both RNA and protein turnovers were accelerated at least twofold in WI-38 cells deprived of serum, and this increase in turnover was inhibited by NH/sub 4/Cl. These results are consistent with two pathways for RNA turnover, oe of them being nonlysosomal and the other being lyosome mediated (NH/sub 4/Cl sensitive), as has been suggested for protein turnover. Also consistent with the notion of two pathways for RNA turnover were findings with I-cells, which are deficient for many lysosomal enzymes, and in which all RNA turnover were nonlysosomal (NH/sub 4/Cl resistant)
Samarel, A.M.; Ogunro, E.A.; Ferguson, A.G.; Lesch, M.
Rate determination of protein synthesis utilizing tracer amino acid incorporation requires accurate assessment of the specific radioactivity of the labeled precursor aminoacyl-tRNA pool. Previously published methods presumably useful for the measurement of any aminoacyl-tRNA were unsuccessful when applied to [ 35 S]methionine, due to the unique chemical properties of this amino acid. Herein we describe modifications of these methods necessary for the measurement of 35 S-aminoacyl-tRNA specific radioactivity from small tissue samples incubated in the presence of [ 35 S]methionine. The use of [ 35 S]methionine of high specific radioactivity enables analysis of the methionyl-tRNA from less than 100 mg of tissue. Conditions for optimal recovery of 35 S-labeled dansyl-amino acid derivatives are presented and possible applications of this method are discussed
Samarel, A.M.; Ogunro, E.A.; Ferguson, A.G.; Lesch, M.
Rate determination of protein synthesis utilizing tracer amino acid incorporation requires accurate assessment of the specific radioactivity of the labeled precursor aminoacyl-tRNA pool. Previously published methods presumably useful for the measurement of any aminoacyl-tRNA were unsuccessful when applied to (/sup 35/S)methionine, due to the unique chemical properties of this amino acid. Herein we describe modifications of these methods necessary for the measurement of /sup 35/S-aminoacyl-tRNA specific radioactivity from small tissue samples incubated in the presence of (/sup 35/S)methionine. The use of (/sup 35/S)methionine of high specific radioactivity enables analysis of the methionyl-tRNA from less than 100 mg of tissue. Conditions for optimal recovery of /sup 35/S-labeled dansyl-amino acid derivatives are presented and possible applications of this method are discussed.
Bischoff, Rainer; Mclaughlin, L.W.
Modification of approximately 65% of the amine groups of an aminopropylsilyl bonded-phase silica high-performance liquid chromatographic anion exchanger (APS-Hypersil) with organic acids containing n-alkyl moieties of different chain lengths, results in mixed mode chromatographic matrices of varying
Kovalska, Vladyslava; Kuperman, Marina; Varzatskii, Oleg; Kryvorotenko, Dmytro; Kinski, Elisa; Schikora, Margot; Janko, Christina; Alexiou, Christoph; Yarmoluk, Sergiy; Mokhir, Andriy
A series of monomethine, trimethine- and styrylcyanine dyes based on a [1,10]phenanthroline moiety was synthesized, characterized and investigated as potential fluorescent probes for nucleic acids in cell free settings and in cells. The dyes were found to be weakly fluorescent in the unbound state, whereas upon the binding to dsDNA or RNA their emission intensity raised up to 50 times (for monomethine benzothiazole derivative FT1 complexed with RNA). The strongest fluorescence intensity in assemblies with dsDNA and RNA was observed for the trimethine benzothiazole derivative FT4. The quantum yield of FT4 fluorescence in its complex with dsDNA was found to be 1.5% and the binding constant (K b) was estimated to be 7.9 × 104 M-1 that is a typical value for intercalating molecules. The FT4 dye was found to be cell membrane permeable. It stains RNA rich components—the nucleoli and most probably the cytoplasmic RNA. FT4 bound to RNAs delivers a very strong fluorescence signal, which makes this easily accessible dye a potentially useful alternative to known RNA stains, e.g. expensive SYTO® 83. The advantage of FT4 is its easy synthetic access including no chromatographic purification steps, which will be reflected in its substantially lower price.
Naghshineh, Elham; Khorvash, Elahe; Kamali, Sara
Background: The aim of the present study was to comparison between cell-free placental messenger ribonucleic acid (mRNA) and Doppler ultrasound for the prediction of placental invasion in women with placenta accreta. Materials and Methods: In this cross-sectional study, 50 pregnant women at risk for placenta accreta underwent color Doppler and assessment of cell-free placental mRNA. Real-time reverse-transcription polymerase chain reaction was used for measurement of cell-free placental m...
Lemieszek, Marta Kinga; Ribeiro, Miguel; Marques, Guilhermina; Nunes, Fernando Milheiro; Pożarowski, Piotr; Rzeski, Wojciech
One of the relatively new and promising strategies of cancer treatment is chemoprevention, which involves the use of natural or synthetic compounds to block, inhibit or reverse carcinogenesis. A valuable and still untapped source of chemopreventive compounds seems to be edible mushrooms belonging to higher Basidiomycetes. Boletus edulis biopolymers extracted with hot water and purified by anion-exchange chromatography showed antiproliferative activity in colon cancer cells, but only fraction BE3, mostly composed of ribonucleic acids, was able to inhibit DNA synthesis in HT-29 cells. The present work aims to elucidate the molecular mechanism of this Boletus edulis ribonucleic acid fraction and in this sense flow cytometry and western blotting were applied to cell cycle analysis in HT-29 cells. We found that the antiproliferative ability of fraction BE3 observed in HT-29 cells was associated with the modulation of expression of cell cycle regulatory proteins (Cyclin D1, Cyclin A, p21 and p27) leading to cell accumulation in the S phase of the cell cycle. Furthermore, the BE3 fraction showed effective silencing of the signal transduction in an MAPK/Erk pathway in HT-29 and LS180 colon cancer cell lines. Thus, the previously and currently obtained results indicate that the BE3 fraction from Boletus edulis has great potential and needs to be further exploited through animal and clinical studies in order to develop a new efficient and safe therapeutic strategy for people who have been threatened by or suffered from colon cancer.
U.S. Environmental Protection Agency — data for figures 1-8 in journal article "Assessment of port-related air quality impacts: geographic analysis of population", International Journal of Environment and...
Wang, Xiaojing; Li, Wei; Ma, Liangkun; Ping, Fan; Liu, Juntao; Wu, Xueyan; Mao, Jiangfeng; Wang, Xi; Nie, Min
Emerging evidence has suggested that the genetic background of gestational diabetes mellitus (GDM) was analogous to type 2 diabetes mellitus. In contrast to type 2 diabetes mellitus, the genetic studies for GDM were limited. Accordingly, the aim of the present study was to extensively explore the influence of micro-ribonucleic acid-binding single-nucleotide polymorphisms (SNPs) in type 2 diabetes mellitus candidate loci on GDM susceptibility in Chinese. A total of 839 GDM patients and 900 controls were enrolled. Six micro-ribonucleic acid-binding SNPs were selected from 30 type 2 diabetes mellitus susceptibility loci and genotyped using TaqMan allelic discrimination assays. The minor allele of three SNPs, PAX4 rs712699 (OR 1.366, 95% confidence interval 1.021-1.828, P = 0.036), KCNB1 rs1051295 (OR 1.579, 95% confidence interval 1.172-2.128, P = 0.003) and MFN2 rs1042842 (OR 1.398, 95% confidence interval 1.050-1.862, P = 0.022) were identified to significantly confer higher a risk of GDM in the additive model. The association between rs1051295 and increased fasting plasma glucose (b = 0.006, P = 0.008), 3-h oral glucose tolerance test plasma glucose (b = 0.058, P = 0.025) and homeostatic model assessment of insulin resistance (b = 0.065, P = 0.017) was also shown. Rs1042842 was correlated with higher 3-h oral glucose tolerance test plasma glucose (b = 0.056, P = 0.028). However, no significant correlation between the other included SNPs (LPIN1 rs1050800, VPS26A rs1802295 and NLRP3 rs10802502) and GDM susceptibility were observed. The present findings showed that micro-ribonucleic acid-binding SNPs in type 2 diabetes mellitus candidate loci were also associated with GDM susceptibility, which further highlighted the similar genetic basis underlying GDM and type 2 diabetes mellitus. © 2018 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd.
Li, Huinan; Wu, Cheng; Aramayo, Rodolfo; Sachs, Matthew S; Harlow, Mark L
Synaptic vesicles (SVs) are neuronal presynaptic organelles that load and release neurotransmitter at chemical synapses. In addition to classic neurotransmitters, we have found that synaptic vesicles isolated from the electric organ of Torpedo californica, a model cholinergic synapse, contain small ribonucleic acids (sRNAs), primarily the 5' ends of transfer RNAs (tRNAs) termed tRNA fragments (trfRNAs). To test the evolutionary conservation of SV sRNAs we examined isolated SVs from the mouse central nervous system (CNS). We found abundant levels of sRNAs in mouse SVs, including trfRNAs and micro RNAs (miRNAs) known to be involved in transcriptional and translational regulation. This discovery suggests that, in addition to inducing changes in local dendritic excitability through the release of neurotransmitters, SVs may, through the release of specific trfRNAs and miRNAs, directly regulate local protein synthesis. We believe these findings have broad implications for the study of chemical synaptic transmission.
Full Text Available Synaptic vesicles (SVs are presynaptic organelles that load and release small molecule neurotransmitters at chemical synapses. In addition to classic neurotransmitters, we have demonstrated that SVs isolated from the Peripheral Nervous Systems (PNS of the electric organ of Torpedo californica, a model cholinergic synapse, and SVs isolated from the Central Nervous System (CNS of Mus musculus (mouse contain small ribonucleic acids (sRNAs; ≤50 nucleotides (Scientific Reports, 5:1–14(14918 Li et al. (2015 . Our previous publication provided the five most abundant sequences associated with the T. californica SVs, and the ten most abundant sequences associated with the mouse SVs, representing 59% and 39% of the total sRNA reads sequenced, respectively. We provide here a full repository of the SV sRNAs sequenced from T. californica and the mouse deposited in the NCBI as biosamples. Three data studies are included: SVs isolated from the electric organ of T. californica using standard techniques, SVs isolated from the electric organ of T. californica using standard techniques with an additional affinity purification step, and finally, SVs isolated from the CNS of mouse. The three biosamples are available at https://www.ncbi.nlm.nih.gov/biosample/ SRS1523467, SRS1523466, and SRS1523472 respectively.
Su, Guoming; Fu, Zhuqing; Hu, Liren; Wang, Yueying; Zhao, Zuguo; Yang, Weiqing
We aim to evaluate the accuracy of the 16S ribosomal ribonucleic acid (rRNA) gene polymerase chain reaction (PCR) test in the diagnosis of bloodstream infections through a systematic review and meta-analysis. A computerized literature search was conducted to identify studies that assessed the diagnostic value of 16S rRNA gene PCR test for bloodstream infections. Study quality was assessed using the revised Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool. We calculated the sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR) and their 95% confidence intervals (95% CI) for each study. Summary receiver operating characteristic (SROC) curve was used to summarize overall test performance. Statistical analysis was performed in Meta-DiSc 1.4 and Stata/SE 12.0 software. Twenty-eight studies were included in our meta-analysis. Using random-effect model analysis, the pooled sensitivity, specificity, PLR, NLR, and DOR were 0.87 (95% CI, 0.85-0.89), 0.94 (95% CI, 0.93-0.95), 12.65 (95% CI, 8.04-19.90), 0.14 (95% CI, 0.08-0.24), and 116.76 (95% CI, 52.02-262.05), respectively. The SROC curve indicated that the area under the curve (AUC) was 0.9690 and the maximum joint sensitivity and specificity (Q*) was 0.9183. In addition, heterogeneity was statistically significant but was not caused by the threshold effect. Existing data suggest that 16S rRNA gene PCR test is a practical tool for the rapid screening of sepsis. Further prospective studies are needed to assess the diagnostic value of PCR amplification and DNA microarray hybridization of 16S rRNA gene in the future.
Naghshineh, Elham; Khorvash, Elahe; Kamali, Sara
The aim of the present study was to comparison between cell-free placental messenger ribonucleic acid (mRNA) and Doppler ultrasound for the prediction of placental invasion in women with placenta accreta. In this cross-sectional study, 50 pregnant women at risk for placenta accreta underwent color Doppler and assessment of cell-free placental mRNA. Real-time reverse-transcription polymerase chain reaction was used for measurement of cell-free placental mRNA in maternal plasma. Based on the findings at cesarean delivery and histological examination, patients were divided into two groups of women with and without placenta accrete. To compare of the mean of mRNA levels between the two groups we used independent t-test and to compare of the mean of age and gestational age at sonography we used Mann-Whitney test. For determination of sensitivity and specificity and the cut-off point of mRNA levels we used the receiver operating characteristic curve. A total of 50 women with a mean age of 30.24 ± 4.905 years entered the study and 12 (24%) patients were diagnosed with placenta accreta. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of Doppler ultrasound were 83.3%, 78.9%, 56% and 94%, respectively. Results of our study showed if we consider a cut-off point equal to 3.325, with sensitivity and specificity of 0.917 and 0.789, respectively and the sensitivity, specificity, PPV and NPV of mRNA with were cut-off point of 3.325 were 91.7%, 78.9%, 57.9% and 96.8%, respectively. Cell-free mRNA is an acceptable, easy made, functional test with sensitivity, specificity, PPV and NPV more than Doppler ultrasound for diagnosis and prediction of incidence of placenta accrete and we recommend the use of cell-free mRNA test for diagnosis of placenta accreta.
Nakamura, Tsutomu; Sakaeda, Toshiyuki; Horinouchi, Masanori; Tamura, Takao; Aoyama, Nobuo; Shirakawa, Toshiro; Matsuo, Masafumi; Kasuga, Masato; Okumura, Katsuhiko
The effect of the C3435T mutation at exon 26 of the MDR1 gene on the expression levels of MDR1 messenger ribonucleic acid (mRNA) was evaluated by means of real-time polymerase chain reaction in 51 biopsy specimens of duodenum obtained from 13 healthy Japanese subjects. The mRNA levels of MDR1 were 0.38 +/- 0.15, 0.56 +/- 0.14, and 1.13 +/- 0.42 (mean value +/- SE) in the subjects with the homozygote of wild-type allele (C/C), compound heterozygote with mutant T allele (C/T), and the homozygote of the mutant allele (T/T), respectively, reasonably explaining the lower digoxin serum concentration after administration of a single oral dose to subjects harboring a mutant T allele. Good correlation (r =.797; P CYP3A4 in the individual biopsy specimens. This finding suggested a lower plasma concentration of the substrates for CYP3A4 in subjects harboring the C3435T mutation of the MDR1 gene.
Saw palmetto extract enhances erectile responses by inhibition of phosphodiesterase 5 activity and increase in inducible nitric oxide synthase messenger ribonucleic acid expression in rat and rabbit corpus cavernosum.
Yang, Surong; Chen, Changrui; Li, Yiying; Ren, Zhenghua; Zhang, Yungang; Wu, Gantong; Wang, Hao; Hu, Zhenzhen; Yao, Minghui
To evaluate whether saw palmetto extract (SPE) relaxes corpus cavernosum and explore the underlying mechanisms. Forty Sprague-Dawley rats and 30 New Zealand rabbits were randomly allocated into 3 SPE-treated groups (low-, middle-, and high-dose) and 1 saline-treated control group. SPE was administered intragastrically for 7 consecutive days. Another 23 rats treated with sildenafil were used to appraise the erectile response to electrical stimulation of nerves in the corpus cavernosum. The erectile functions of rats and rabbits were evaluated 24 hours after the last SPE administration or 15 minutes after intragastric sildenafil. Outcome measures included corpus cavernosum electrical activity recording, phosphodiesterase 5 (PDE5) activity detected by the colorimetric quantitative method, and messenger ribonucleic acid (mRNA) expression level for PDE5 and inducible nitric oxide synthase (iNOS) determined using real-time polymerase chain reaction. In the SPE-treated animals, the relaxant response to electrical stimulation of nerves in the corpus cavernosum, reflected by the amplitude of the electrical activity within the cavernosum, was significantly and dose-dependently augmented. Similar effects were observed in the sildenafil-treated rats. PDE5 activity in rat and rabbit corpus cavernosum tissues was significantly and dose-dependently inhibited in SPE-treated animals, whereas the iNOS mRNA level increased compared with the saline group. PDE5 mRNA, however, was only significantly enhanced in the rats treated with the middle dose of SPE. The results suggest that SPE may have potential application value for the prevention or treatment of erectile dysfunction through an increase in iNOS mRNA expression and inhibition of PDE5 activity in corpus cavernosum smooth muscles. Copyright © 2013 Elsevier Inc. All rights reserved.
Ra, Hyejun; Gonzalez-Gonzalez, Emilio; Smith, Bryan R.; Gambhir, Sanjiv S.; Kino, Gordon S.; Solgaard, Olav; Kaspar, Roger L.; Contag, Christopher H.
Transgenic reporter mice and advances in imaging instrumentation are enabling real-time visualization of cellular mechanisms in living subjects and accelerating the development of novel therapies. Innovative confocal microscope designs are improving their utility for microscopic imaging of fluorescent reporters in living animals. We develop dual-axis confocal (DAC) microscopes for such in vivo studies and create mouse models where fluorescent proteins are expressed in the skin for the purpose of advancing skin therapeutics and transdermal delivery tools. Three-dimensional image volumes, through the different skin compartments of the epidermis and dermis, can be acquired in several seconds with the DAC microscope in living mice, and are comparable to histologic analyses of reporter protein expression patterns in skin sections. Intravital imaging with the DAC microscope further enables visualization of green fluorescent protein (GFP) reporter gene expression in the skin over time, and quantification of transdermal delivery of small interfering RNA (siRNA) and therapeutic efficacy. Visualization of transdermal delivery of nucleic acids will play an important role in the development of innovative strategies for treating skin pathologies.
Comparing the effects of tetrabromobisphenol-A, bisphenol A, and their potential replacement alternatives, TBBPA-bis(2,3-dibromopropyl ether) and bisphenol S, on cell viability and messenger ribonucleic acid expression in chicken embryonic hepatocytes.
Ma, Melissa; Crump, Doug; Farmahin, Reza; Kennedy, Sean W
A market for alternative brominated flame retardants (BFRs) has emerged recently due to the phase out of persistent and inherently toxic BFRs. Several of these replacement compounds have been detected in environmental matrices, including wild birds. A chicken embryonic hepatocyte (CEH) assay was utilized to assess the effects of the BFR, tetrabromobisphenol-A (TBBPA), and its replacement alternative, tetrabromobisphenol A bis(2,3-dibromopropyl ether [TBBPA-DBPE]) on cell viability and messenger ribonucleic acid (mRNA) expression. Bisphenol A (BPA) and 1 of its replacement alternatives, bisphenol S (BPS), were also screened for effects. Both TBBPA and BPA decreased CEH viability with calculated median lethal concentration (LC50) values of 40.6 μM and 61.7 μM, respectively. However, the replacement alternatives, TBBPA-DBPE and BPS, did not affect cell viability (up to 300 μM). Effects on mRNA expression were determined using an Avian ToxChip polymerse chain reaction (PCR) array and a real-time (RT)-PCR assay for the estrogen-responsive genes, apolipoproteinII (ApoII) and vitellogenin (Vtg). A luciferase reporter gene assay was used to assess dioxin-like effects. Tetrabromobisphenol-A altered mRNA levels of 4 genes from multiple toxicity pathways and increased luciferase activity in the luciferase reporter gene assay, whereas its alternative, TBBPA-DBPE, only altered 1 gene on the array, Cyp1a4, and increased luciferase activity. At 300 μM, a concentration that decreased cell viability for TBBPA and BPA, the BPA replacement, BPS, altered the greatest number of transcripts, including both ApoII and Vtg. Bisphenol A exposure did not alter any genes on the array but did up-regulate Vtg at 10 μM. Characterization of the potential toxicological and molecular-level effects of these compounds will ideally be useful to chemical regulators tasked with assessing the risk of new and existing chemicals. © 2014 SETAC.
Duarte, Ana Rita C; Maniglio, Devid; Sousa, Nuno; Mano, João F; Reis, Rui L; Migliaresi, Claudio
This study investigated the preparation of ordered patterned surfaces and/or microspheres from a natural-based polymer, using the breath figure and reverse breath figure methods. Poly(D,L-lactic acid) and starch poly(lactic acid) solutions were precipitated in different conditions - namely, polymer concentration, vapor atmosphere temperature and substrate - to evaluate the effect of these conditions on the morphology of the precipitates obtained. The possibility of fine-tuning the properties of the final patterns simply by changing the vapor atmosphere was also demonstrated here using a range of compositions of the vapor phase. Porous films or discrete particles are formed when the differences in surface tension determine the ability of polymer solution to surround water droplets or methanol to surround polymer droplets, respectively. In vitro cytotoxicity was assessed applying a simple standard protocol to evaluate the possibility to use these materials in biomedical applications. Moreover, fluorescent microscopy images showed a good interaction of cells with the material, which were able to adhere on the patterned surfaces after 24 hours in culture. The development of patterned surfaces using the breath figure method was tested in this work for the preparation of both poly(lactic acid) and a blend containing starch and poly(lactic acid). The potential of these films to be used in the biomedical area was confirmed by a preliminary cytotoxicity test and by morphological observation of cell adhesion.
U.S. Environmental Protection Agency — This is an R statistics package script that allows the reproduction of Figure 5. The script includes the links to large NetCDF files that the figures access for O3,...
U.S. Environmental Protection Agency — Two files provided. The ENS.tar file contains text data files (*.csv) used to create Figure 7 and Figure 8. The Figure7.txt is an R script that reads these files and...
U.S. Environmental Protection Agency — The Figure.tar.gz contains a directory for each WRF ensemble run. In these directories are *.csv files for each meteorology variable examined. These are comma...
U.S. Environmental Protection Agency — R script for the reproduction of Figure6. This script accesses archived CMAQ and WRF model output on US EPA's HPC sol computer system and plots forward trajectories...
Methylation of ribonucleic acid by the carcinogens dimethyl sulphate, N-methyl-N-nitrosourea and N-methyl-N′-nitro-N-nitrosoguanidine. Comparisons of chemical analyses at the nucleoside and base levels
Lawley, P. D.; Shah, S. A.
1. The following methods for hydrolysis of methyl-14C-labelled RNA, and for chromatographic isolation and determination of the products, were investigated: enzymic digestion to nucleosides at pH6 or 8; alkaline hydrolysis and conversion into nucleosides; hydrolysis by acid to pyrimidine nucleotides and purine bases, or completely to bases; chromatography on Dowex 50 (NH4+ form) at pH6 or 8.9, or on Dowex 50 (H+ form), or on Sephadex G-10. 2. The suitability of the various methods for determination of methylation products was assessed. The principal product, 7-methylguanosine, was unstable under the conditions used for determinations of nucleosides. 3- and 7-Methyladenine and 3- and 7-methylguanine are best determined as bases; 1-methyladenine and 3-methylcytosine can be isolated as either nucleosides or bases; O6-methylguanine is unstable under the acid hydrolysis conditions used and can be determined as the nucleoside; 3-methyluracil was detected, but may be derived from methylation of the ionized form of uracil. 3. Differences between the patterns of methylation of RNA and homopolyribonucleotides by the N-methyl-N-nitroso compounds and dimethyl sulphate were found: the nitroso compounds were able to methylate O-6 of guanine, were relatively more reactive at N-7 of adenine and probably at N-3 of guanine, but less reactive at N-1 of adenine, N-3 of cytosine and probably at N-3 of uridine. They probably reacted more with the ribose–phosphate chain, but no products from this were identified. 4. The possible influences of these differences on biological action of the methylating agents is discussed. Nitroso compounds may differ principally in their ability to induce miscoding in the Watson–Crick sense by reaction at O-6 of guanine. Both types of agent may induce miscoding to a lesser extent through methylation at N-3 of guanine; both can methylate N atoms, presumably preventing Watson–Crick hydrogen-bonding. N-Methyl-N-nitrosourea can degrade RNA, possibly
Progesterone receptor membrane component-1 (PGRMC1) is the mediator of progesterone's antiapoptotic action in spontaneously immortalized granulosa cells as revealed by PGRMC1 small interfering ribonucleic acid treatment and functional analysis of PGRMC1 mutations.
Peluso, John J; Romak, Jonathan; Liu, Xiufang
Progesterone (P4) receptor membrane component-1 (PGRMC1) and its binding partner, plasminogen activator inhibitor 1 RNA binding protein (PAIRBP1) are thought to form a complex that functions as membrane receptor for P4. The present investigations confirm PGRMC1's role in this membrane receptor complex by demonstrating that depleting PGMRC1 with PGRMC1 small interfering RNA results in a 60% decline in [(3)H]P4 binding and the loss of P4's antiapoptotic action. Studies conducted on partially purified GFP-PGRMC1 fusion protein indicate that [(3)H]P4 specifically binds to PGRMC1 at a single site with an apparent K(d) of about 35 nm. In addition, experiments using various deletion mutations reveal that the entire PGRMC1 molecule is required for maximal [(3)H]P4 binding and P4 responsiveness. Analysis of the binding data also suggests that the P4 binding site is within a segment of PGRMC1 that is composed of the transmembrane domain and the initial segment of the C terminus. Interestingly, PAIRBP1 appears to bind to the C terminus between amino acids 70-130, which is distal to the putative P4 binding site. Taken together, these data provide compelling evidence that PGRMC1 is the P4 binding protein that mediates P4's antiapoptotic action. Moreover, the deletion mutation studies indicate that each domain of PGRMC1 plays an essential role in modulating PGRMC1's capacity to both bind and respond to P4. Additional studies are required to more precisely delineate the role of each PGRMC1 domain in transducing P4's antiapoptotic action.
6.8. 7.0. 7.2. 7.4. 7.6. 7.8. 8.0. 8.2. 8.4. 8.6. 8.8 ppm. 0.0. 1.8. 9.7. 5.4. 6.9. 8.1. 9.0. 10.8. 3.2. 10.3. Figure S3. NMR titration of DAN-Ia acid with NDI at 30% MeOH in CDCl3. The numbers represent the mole ratios of the DAN-acid to the repeat unit.
Infectious single-stranded RNA isolated from mature purified poliovirus was separated into three fractions by means of chromatography on an ''evaporated'' calcium phosphate column. RNA molecules with a higher degree of secondary structure were detected in two of the fractions as a result of the chromatography. These RNA molecules (1) were resistant to hydrolysis by pancreatic ribonuclease A, (2) retained unchanged the original infectivity for actinomycin D-pretreated cells, (3) were resistant to ultraviolet-light inactivation and (4) were partially resistant to formaldehyde inactivation
Lucy, M.C.; Boyd, C.K.; Koenigsfeld, A.T.; Okamura, C.S.
The somatotropin receptor mRNA is controlled by at least two different gene promoters that generate 2 two variants with different exon 1 sequences (1A and 1B). The location of 1A and 1B somatotropin receptor mRNA within cattle tissues and, hence, the tissue specificity of the 1A and 1B promoters are unknown. In addition, the cDNA sequence of the 1B somatotropin receptor has not been determined. Our objective, therefore, was to sequence a cDNA for the 1B somatotropin receptor and to analyze bovine tissues for expression of 1A and 1B somatotropin receptor mRNA. Twenty adult tissues and six fetal tissues were collected at slaughter from each of four cows and two fetuses. Messenger RNA was analyzed using ribonuclease protection assays. The adult liver expressed both 1A and 1B mRNA. All other adult tissues expressed 1B mRNA but not 1A mRNA. The greatest amount of 1B mRNA was detected in liver and adipose (abdominal and subcutaneous) tissues. Other tissues had approximately one-half to one-tenth of the amount of 1B mRNA in the liver or adipose tissue. Fetal tissues (including fetal liver) expressed 1B mRNA and not 1A mRNA. Based on cDNA sequencing, the protein encoded by the 1A and 1B mRNA was nearly identical. We concluded that 1A somatotropin receptor mRNA is specific to adult bovine liver. Other adult and fetal bovine tissues expressed 1B somatotropin receptor mRNA with a predicted protein sequence that was similar to the 1A somatotropin receptor
Dec 19, 2016 ... South African Journal of Animal Science 2017, 47 (No. 1) ... plasma membrane integrity (PMI), normal apical ridges (NAR) .... contributed to the analysis of the RNA samples and CSP assisted in the revision of the manuscript.
Singhal, R.P.; Griffin, G.D.; Novelli, G.D.
The transfer RNA separation by chromatography on strong-base-polystyrene exchange materials is examined and compared with the widely used reversed-phase chromatography. Results indicate important differences in some transfer RNA (tRNA) elution patterns by the anion-exchange chromatography, as compared with the reversed-phase chromatography. Transfer RNAs containing hydrophobic groups are adsorbed more strongly. The anion exchanger has twice the number of theoretical plates. Single peaks of tRNA/sub 2//sup Glu/ and tRNA/sub 1//sup Phe/ obtained from the reversed-phase column give multiple peaks on polystyrene anion-exchange chromatography. All six leucine tRNAs (Escherichia coli) and differences in tRNA populations synthesized during early and late stages of the dividing lymphocytes from normal human blood can be characterized by the anion-exchange chromatography. Different separation profiles are obtained by two separation systems for tyrosine tRNAs from mouse liver and mouse-plasma-cell tumor. The results indicate that, in contrast to the reversed-phase chromatography, strong-base-polystyrene anion-exchange chromatography is capable of separating tRNAs with minor structural differences.
Helion Povoa Jr.
Full Text Available RNA was determined in red blood cells of man and other mammals. Our report is based on 41 determinations. Red blood cells of rat showed the highest values in comparison with the blood cells of guinea pig, rabbit, horse and sheep which showed the lowest values, and man with intermediate ones. The method used was a combination of Schimidt and Thanhauser and Schneider extractions with the final reactions of pentose with the orcinol reagent colorimetrically measured.O ácido ribonucleico foi dosado em hemátias de mamíferos, num total de 41 casos. Valores altos foram encontrados em hemátias de ratos em comparação com os de cobaia, coelho, cavalo e carneiro. Hemátias humanas apresentaram valores intermediários. Usou-se um método, combinando-se as extrações de Schmidt, Thanhauser e Schneider com a reação final da pentose com o orcinol, lendo-se a côr verde num fotocolorímetro, em 650 milimicra.
Nielsen, Gritt B.
, students' room for participation in their own learning, influenced by demands for efficiency, flexibility and student-centred education. The thesis recasts the anthropological endeavour as one of ‘figuration work'. That is, ‘frictional events' are explored as moments when conflicting figures...
Caldarera, C M; Casti, A; Guarnier, C; Moruzzi, G
The relationship between polyamines and RNA synthesis was studied by considering the action of spermine on histone acetylation in perfused heart. In addition, the effect of methylglyoxal bis(guanylhydrazone), inhibitor of putrescine-activated S-adenosylmethionine decarboxylase activity, on RNA and polyamine specific radioactivity and on acetylation of histone fractions was also investigated in perfused heart. Different concentrations of spermine and/or methylglyoxas bis(guanylhydrazone) were injected into the heart, 15 min after beginning the perfusion. The results demonstrate that spermine stimulates the specific radioactivity of RNA of subcellular fractions. Acetylation of the arginine-rich histone fractions, involved in the regulation of RNA transcription, is enhanced by spermine. The perfusion with methylglyoxal bis(guanylhydrazone) causes a decrease in the specific radioactivity of polyamines and RNA, and in acetylation of histone fractions. However, spermine is able to reverse the methylglyoxal bis(guanylhydrazone) inhibition when injected simultaneously. From these results we may assume a possible role for spermine in the regulation of RNA transcription.
U.S. Environmental Protection Agency — Figures 1-10 and Table 1. This dataset is associated with the following publication: Chang, S.Y., S. Arunachalam, A. Valencia, B. Naess, V. Isakov , M. Breen , T....
U.S. Environmental Protection Agency — Data for Figure 2. This dataset is associated with the following publication: Sarwar, G., D. Kang, K. Foley, D. Schwede, B. Gantt, and R. Mathur. Technical note:...
... Saves Lives Facts & Figures My Blood, Your Blood Blood Donation Types Did you know there is more than one type of blood donation? Learn more about blood donation types here. Blood Safety and Testing The blood supply ...
Greenslade, Thomas B., Jr.
Lissajous Figures are produced by combining two oscillations at right angles to each other. The figures, drawn by mechanical devices called harmonographs, have scientific uses, but are also enjoyed for their own beauty. The author has been working with harmonographs since his undergraduate days, building several of them, lecturing on them and has written articles about them. This book is intended for people who enjoy physics or art or both.
U.S. Environmental Protection Agency — emissions data and removal efficiencies for coal combustion utilizing PM control devices and dry sorbent injection of trona specifically for acid gas control. This...
Macias B, L.R.
The objective of this work, is that starting from a data file coming from a spectra that has been softened, and of the one that have been generated its coordinates to project it in stereographic form, to create the corresponding polar figure making use of the Cyber computer of the ININ by means of the GRAPHOS package. This work only requires a Beta, Fi and Intensity (I) enter data file. It starts of the existence of a softened spectra of which have been generated already with these data, making use of some language that in this case was FORTRAN for the Cyber computer, a program is generated supported in the Graphos package that allows starting of a reading of the Beta, Fi, I file, to generate the points in a stereographic projection and that it culminates with the graph of the corresponding polar figure. The program will request the pertinent information that is wanted to capture in the polar figure just as: date, name of the enter file, indexes of the polar figure, number of levels, radio of the stereographic projection (cms.), crystalline system to which belongs the sample, name the neuter graph file by create and to add the own general data. (Author)
This table taken out from the 1981 annual report 1981 contains an introductory remark on the reorganization of mineral oil statistics up to January 82. It is followed by the tables ranged as follows: refinery capacity and production, crude oil supply, GDR-coverings, import of petroleum products, petroleum consumption, export of petroleum products, transport, oil storage tanks, motor vehicle stock, taxes and tariffs, petroleum export trade, energy consumption and world petroleum numbers. In parts the tables contain comparative figures back to 1950.
Deddi Duto Hartanto
Full Text Available Testimonial advertising seemingly identical with famous figure such as artist%2C sportmen or others. They are all branded as "public figure" because they are well known by public. A lot of advertising creators using public figure in order to gain a high brand awareness. Is the use of public figure in testimonial advertising more profitable? Is their able quite representative for the products they represent ? Abstract in Bahasa Indonesia : Iklan testimonial identik dengan tokoh terkenal%2C baik itu artis%2C tokoh masyarakat%2C olahragawan%2C atau yang lainnya. Semuanya di cap sebagai "publik figur%2C" karena sudah dikenal masyarakat.Banyak kreator iklan menggunakan publik figur dengan harapan dapat mencapai brand awareness yang tinggi. Apakah penggunaan publik figur dalam iklan testimonial lebih menguntungkan ?%2C Apakah peran publik figur (sudah mewakili produk yang dibawakan?. testimonial advertising%2C public figure
Thinking in numbers, figures and systems plays a central part in our - at least scientific – understanding of musical matters. The kind of pre-order that the numbers - and also the systemic thinking - bring along seem to facilitate the access to and dealings with what we understand as fundamental...... to reflect. By means of a critical resume of an earlier analysis of rhythmical implications in Michael Jackson's "Give In To Me" this paper discusses these matters further and reflects upon arithmetic's influences and relevance for our understanding of music....
Whereas most of the data are, naturally, about oil, a few figures concern nuclear energy. There is in Part 1 a flow chart of worldwide primary energy consumption by type, from 1974 to 1986, where nuclear energy consumption can be seen in relation to oil, gas, coal and hydro. The same is also given for the regions of the South. In section 3/18 the numbers of nuclear plants in construction and operation are listed separately for developing countries, centrally planned economies and industrialized countries, for 1986. (qui)
Full Text Available Figures are important experimental results that are typically reported in full-text bioscience articles. Bioscience researchers need to access figures to validate research facts and to formulate or to test novel research hypotheses. On the other hand, the sheer volume of bioscience literature has made it difficult to access figures. Therefore, we are developing an intelligent figure search engine (http://figuresearch.askhermes.org. Existing research in figure search treats each figure equally, but we introduce a novel concept of "figure ranking": figures appearing in a full-text biomedical article can be ranked by their contribution to the knowledge discovery.We empirically validated the hypothesis of figure ranking with over 100 bioscience researchers, and then developed unsupervised natural language processing (NLP approaches to automatically rank figures. Evaluating on a collection of 202 full-text articles in which authors have ranked the figures based on importance, our best system achieved a weighted error rate of 0.2, which is significantly better than several other baseline systems we explored. We further explored a user interfacing application in which we built novel user interfaces (UIs incorporating figure ranking, allowing bioscience researchers to efficiently access important figures. Our evaluation results show that 92% of the bioscience researchers prefer as the top two choices the user interfaces in which the most important figures are enlarged. With our automatic figure ranking NLP system, bioscience researchers preferred the UIs in which the most important figures were predicted by our NLP system than the UIs in which the most important figures were randomly assigned. In addition, our results show that there was no statistical difference in bioscience researchers' preference in the UIs generated by automatic figure ranking and UIs by human ranking annotation.The evaluation results conclude that automatic figure ranking and user
Swann, P F
1. By 1h after administration of ethionine to the female rat the appearance of newly synthesized 18SrRNA in the cytoplasm is completely inhibited. This is not caused by inhibition of RNA synthesis, for the synthesis of the large ribosomal precursor RNA (45S) and of tRNA continues. Cleavage of 45S RNA to 32S RNA also occurs, but there was no evidence for the accumulation of mature or immature rRNA in the nucleus. 2. The effect of ethionine on the maturation of rRNA was not mimicked by an inhibitor of protein synthesis (cycloheximide) or an inhibitor of polyamine synthesis [methylglyoxal bis(guanylhydrazone)]. 3. Unlike the ethionine-induced inhibition of protein synthesis, this effect was not prevented by concurrent administration of inosine. A similar effect could be induced in HeLa cells by incubation for 1h in a medium lacking methionine. The ATP concentration in these cells was normal. From these two observations it was concluded that the effect of etionine on rRNA maturation is not caused by an ethionine-induced lack of ATP. It is suggested that ethionine, by lowering the hepatic concentration of S-adenosylmethionine, prevents methylation of the ribosomal precursor. The methylation is essential for the correct maturation of the molecule; without methylation complete degradation occurs. PMID:1212195
RNA) from raw fresh semen and frozen-thawed boar semen, using a protocol comprising the conventional TRIzol assay and a membrane-based technique, the PureLink RNA mini kit. Bioanalyzer profile revealed that the sperm RNA size ...
Douthwaite, S; Garrett, R A
The structures of 5S ribosomal RNAs from Escherichia coli and Bacillus stearothermophilus were examined by using ribonucleases A, T1, and T2 and a double helix specific cobra venom ribonuclease. By using both 5' and 3'-32P-end labeling methods and selecting for digested but intact 5S RNA molecules...... evidence for three of the helical regions of the Fox and Woese model of 5S RNA [Fox, G. E., & Woese, C. (1975) Nature (London) 256, 505] and support other important structural features which include a nucleotide looped out from a helical region which has been proposed as a recognition site for protein L18....
Douthwaite, S; Christensen, A; Garrett, R A
The binding sites of ribosomal proteins L18 and L25 on 5S RNA from Escherichia coli were probed with ribonucleases A, T1, and T2 and a double helix specific cobra venom endonuclease. The results for the protein-RNA complexes, which were compared with those for the free RNA [Douthwaite, S...... stearothermophilus 5S RNA. Several protein-induced changes in the RNA structures were identified; some are possibly allosteric in nature. The two prokaryotic 5S RNAs were also incubated with total 50S subunit proteins from E. coli and B. stearothermophilus ribosomes. Homologous and heterologous reconstitution....... stearothermophilus 5S RNA, which may have been due to a third ribosomal protein L5....
Background and Objectives: Hepatitis C virus (HCV) is a major cause of chronic liver disease, cirrhosis and hepatocellular cancer worldwide, with associated significant morbidity and mortality. It is estimated that 3% of the world population have HCV, and in Nigeria, prevalence rates of between 4.7-20% have been reported ...
Dayhoff, M. O.; Schwartz, R. M.
The chemical structures of ferredoxin, 5S ribosomal RNA, and c-type cytochrome sequences have been employed to construct a phylogenetic tree which connects all major photosynthesizing organisms: the three types of bacteria, blue-green algae, and chloroplasts. Anaerobic and aerobic bacteria, eukaryotic cytoplasmic components and mitochondria are also included in the phylogenetic tree. Anaerobic nonphotosynthesizing bacteria similar to Clostridium were the earliest organisms, arising more than 3.2 billion years ago. Bacterial photosynthesis evolved nearly 3.0 billion years ago, while oxygen-evolving photosynthesis, originating in the blue-green algal line, came into being about 2.0 billion years ago. The phylogenetic tree supports the symbiotic theory of the origin of eukaryotes.
Millan Scarabeli Alves Coelho da Silva
Full Text Available Rotavirus has been considered the main agent of infectious diarrhea especially among younger children. We addressed the prevalence of rotavirus-associated diarrhea and the diversity of circulating electropherotypes by immunochromatography and RNA electrophoresis. Stool samples were taken from 391 children (267 with diarrhea from the lower socioeconomic stratum who sought treatment in the Hospital Infantil João Paulo II/Belo Horizonte, during 2005 and 2006. Rotavirus was detected in 79/20.2% of subjects, 64/24.0% with diarrhea and 15/12.1% with no diarrhea. The virus was strongly associated with diarrhea (p = 0.003. A total of 76/19.4% and 69/17.6% rotavirus-positive children were identified by immunochromatography and electrophoresis, respectively. Rotavirus-associated diarrhea was more frequently detected in dry months (p < 0.001 and almost exclusively in children aged up to three years. Long profile strains prevailed (54/78.3% but a shift toward short electropherotype was identified. Despite the decrease seen in 2006, rotavirus infection is still very common in our area. Although viral RNA electrophoresis is useful as a typing method, it should not be used exclusively in the diagnosis of rotavirus infection. We confirmed a shift from long to short profile strains, as already described for other South American countries.
Mountjoy, Kathleen G; Jenny Wu, C-S; Dumont, Laurence M; Wild, J Martin
We determined melanocortin-4 receptor (MC4-R) mRNA ontogeny in the rat using in situ hybridization and a rat MC4-R riboprobe and showed numerous peripheral sites of expression for MC4-R. The developing heart showed MC4-R mRNA expression as early as embryonic day (E) 14. In the lungs of E16-E20 fetuses, the cells surrounding developing bronchi expressed relatively strong in situ signal. Muscles associated with the respiratory system such as diaphragm and intercostal muscle expressed MC4-R mRNA as early as E14. Occipital and tongue muscles, in particular the genioglossus, showed diffuse signal at E15-E20. In the eye, a discrete signal was detected in an outer neuroblastic layer which may correspond to retina or extraocular muscle. Developing limb buds expressed relatively strong signal at E14, whereas skull bone and joint capsules of the paw of the forelimb showed signal at E18-E20. Using RT-PCR and ribonuclease protection assays, we determined that MC4-R mRNA is also expressed in adult rat heart, lung, kidney, and testis. The expression of the MC4-R in cardiorespiratory, musculoskeletal, and integumentary systems supports functional roles for the MC4-R in addition to its roles in appetite, weight control, and regulation of linear growth.
Rodriguez-Esteban, Raul; Iossifov, Ivan
Figures from biomedical articles contain valuable information difficult to reach without specialized tools. Currently, there is no search engine that can retrieve specific figure types. This study describes a retrieval method that takes advantage of principles in image understanding, text mining and optical character recognition (OCR) to retrieve figure types defined conceptually. A search engine was developed to retrieve tables and figure types to aid computational and experimental research. http://iossifovlab.cshl.edu/figurome/.
Hawkins, Ed; McNeall, Doug
In the words of the UK government chief scientific adviser "Science is not finished until it's communicated" (Walport 2013). The tools to produce good visual communication have never been so easily accessible to scientists as at the present. Correspondingly, it has never been easier to produce and disseminate poor graphics. In this presentation, we highlight some good practice and offer some practical advice in preparing scientific figures for presentation to peers or to the public. We identify common mistakes in visualisation, including some made by the authors, and offer some good reasons not to trust defaults in graphics software. In particular, we discuss the use of colour scales and share our experiences in running a social media campaign (http://tiny.cc/endrainbow) to replace the "rainbow" (also "jet", or "spectral") colour scale as the default in (climate) scientific visualisation.
Neste Corporation's net sales during 1991 totalled USD 12.6 billion, an increase of 11 % over the figure for 1990. The largest growth in net sales took place in Neste Oil's trading activities and sales of in-house-produced crude oil. In the chemicals sector. particular growth was recorded in resins production. Gas, Shipping and Exploration and Production performed slightly better than during 1990. Oil's performance remained satisfactory. The performance of Chemicals, however, fell back considerably, primarily, as a result of the worldwide drop in prices in the petrochemicals and plastics industries. As a result, the Corporation's overall result was substantially below the good level recorded in 1990. The Corporation's operating margin totalled USD 650 million
Space and Naval Warfare Systems Command The Cybersecurity Challenge in Acquisition Sonia Kaestner, Adjunct Professor, McDonough School of Business ...qÜáêíÉÉåíÜ=^ååì~ä= ^Åèìáëáíáçå=oÉëÉ~êÅÜ= póãéçëáìã= tÉÇåÉëÇ~ó=pÉëëáçåë= sçäìãÉ=f= = Cybersecurity Figure of Merit CAPT Brian Erickson, USN, SPAWAR...the Acquisition Research Program of the Graduate School of Business & Public Policy at the Naval Postgraduate School. To request defense acquisition
Mohammad Takdir Ilahi
Full Text Available In a pesantren (Islamic boarding school, kiai is an strategic element. Javanese kiai mainly believe that a pesantren is a small palace where he becomes the ultimate source of power and authority. Even though he lives in a rural village, he becomes a member of elite group in social, politic and economic sides in the society. Kiai who leads big pesantren has successfully enlarged their power in term of nation so kiai could be accepted in national elite. The position of kiai is higher among all pesantren elements. The degree as an Islamic scholar is exactly a sacred degree in pesantren culture and tradition. Without his figure, it is impossible for a pesantren to develop and survive. Kiai holds an ultimate position on educate the behavior and morality of the santri (students to be qualified and compatible Muslims generation. Kiai is not only a leader but he is also the man behind the leadership itself in supporting the progress of Islamic education institution for Muslims generations.
Lavergne, R.; Meuric, L.; Scherrer, S.; Paquel, V.; Louati, S.; Thienard, H.
This document gathers a series of articles dedicated to the situation of the energy sector in France at the end of 2004: -) the energy balance sheet, -) the trend concerning energy consumption since 1973, -) the energy bill, -) figures about electrical power, -) figures about natural gas, -) figures about solid fossil fuels, -) figures about oil, and -) figures about renewable energies. The important fact to note is that the energy bill has soared by 24.1% to reach 28.35 milliard euros which represents 1.75% of the gross national product (PIB). The evolution over the year 2004 of the factors that contribute to the level of the energy bill is: - the import-export energy quantity differential: +7.5%, - the import-export energy cost differential (in Usa dollar): +27.1%, and - the fall of the dollar: -9.1%. (A.C.)
Cabrera B, E.; Macias B, L.R.
In the present work it's shown the possibility of obtaining a pole-figure from the data generated in a conventional X-ray equipment, with a commercial goniometer and no electronic device to process the data. The way to plot the pole-figure on-line is by means of measuring the diffractogram and plot manually the stereographic projections. The atainable precision is very low in such a cumbersome process. In this paper we substitute such method by storing the data in a punched tape from a conventional teletype. The data is processed in a computer and the pole-figure is recorded by a plotter attached to the computer. (author)
Truelsen, T.A.; Galston, A.W.
after the pretreatment showed that the attered growth patterns could be ascribed to declining auxin content with time, but not to thc actual concentration in the sections. The results indicate that the metabolic activation brought about by IAA leads to its own disappearance. Such a phenomenon...
Full Text Available ... Home Text size: A A A 2018 Alzheimer's Disease Facts and Figures Download the full report: Download ... about memory loss? KNOW THE 10 SIGNS Alzheimer's Disease Facts in Each State The 2018 Alzheimer's Disease ...
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Promotional activities are very often based on advertising and diverse types of public relations. In order to attract consumers' attention and achieve communication goals set by the corporate strategy, advertisers frequently use rhetorical elements in advertising discourse. The advertisers try to convey a desired message and to communicate with the recipient of the message by using various rhetorical figures. It is argued that understanding the structure and function of rhetorical figur...
”Figured worlds”, altså forestillede verdener, er et teoretisk begreb, som i øjeblikket dukker op i flere og flere forskningssammenhænge. Det bliver anvendt på mange forskellige måder både inden for uddannelsesforskning og i forskning i literacy.......”Figured worlds”, altså forestillede verdener, er et teoretisk begreb, som i øjeblikket dukker op i flere og flere forskningssammenhænge. Det bliver anvendt på mange forskellige måder både inden for uddannelsesforskning og i forskning i literacy....
Moormann, Peter Paul
Fifty-eight figure skating trainers from fifteen different countries acted as volunteers in this study on choreography styles. The styles were based on reports of artistic-creative strategies in composing music, drawing, writing poems or novels, and in making dances. The prevalence of the Mozartian (at the onset the choreographer already has a…
Naglieri, Jack A.
Responds to previous article (Motta, Little, and Tobin, this issue) which reviewed data-based studies on figure drawings and found little support for their validity or use in assessing personality, behavior, emotion, or intellectual functioning. Contends that article is unacceptable for publication in present form, with main criticism being that…
Full Text Available Promotional activities are very often based on advertising and diverse types of public relations. In order to attract consumers' attention and achieve communication goals set by the corporate strategy, advertisers frequently use rhetorical elements in advertising discourse. The advertisers try to convey a desired message and to communicate with the recipient of the message by using various rhetorical figures. It is argued that understanding the structure and function of rhetorical figures in advertising requires a "text- and reader-aware approach". The use of rhetorical figures in advertising has been overlooked in consumer research. This paper shows that the use of rhetorical elements in the advertising discourse is very frequent, but at the same time it is questioned if the function of the rhetorical figures is just a communication with the target market (which is a base of communication models and if the consequences of linguistic influences are much more serious. The complex nature of advertising language with various rhetorical figures (thropes and schemes do not just stimulate recipients to demonstrate a desirable behavior, but indirectly it constructs a concept of desirable lifestyle and it induces them to identify themselves with the explained model. Moreover, the analyzed corpus included advertising slogans of social responsible companies as well as advertising campaigns with elements of diverse ideologies. In the time of digitization and a rapid information flow, consumer's attention is less dedicated to the advertising messages. Therefore, it should be expected that in the future advertisers will have to adjust linguistic, audio and visual techniques to the unfocused message recipients.
With manufacturing facilities in over 40 countries and a sales network in over 100, AREVA offers customers technological solutions for nuclear power generation and electricity transmission and distribution. The group also provides interconnect systems to the telecommunications, computer and automotive markets. This document presents the sales figures of the group for the third quarter of 2005: sales revenues in the front end division, in the reactor and services division, in the back end division and in the transmission and distribution division
The argument: every metaphor and metaphoric idiom grows out of and is nourished by a seminal metonymy. Since these germinating seeds-and the mineral elements which feed them-work under cover, we tend to overlook them when we feast off harvests cropped from the fields of metaphor: and we therefore forget to take into account the radical fecundity of the metonymic germ. This essay attempts to remedy such forgetfulness. At the same time, it also claims that metonymy (a figure of rhetoric) and im...
Full Text Available Alors même que l’ensemble du personnel gouvernemental et parlementaire est sujet à une relative désaffection de la part des citoyens, les maires français jouissent, on le sait, d’une popularité qui fait d’eux les figures centrales de la scène politique. Au-delà de la décentralisation, qui a souvent renforcé leur image de décideurs, ils ont su tirer parti de la dimension identitaire qui caractérise l’échelon communal pour devenir les acteurs indispensables de la vie locale. ...
Hunter, Matthew C
The experimental philosopher Robert Hooke (1635-1703) is known to have apprenticed to the leading painter Peter Lely on his first arrival in London in the late 1640s. Yet the relevance of Hooke's artistic training to his mature draughtsmanship and identity has remained unclear. Shedding light on that larger interpretive problem, this article argues for the attribution to Hooke of a figural drawing now in Tate Britain (T10678). This attributed drawing is especially interesting because it depicts human subjects and bears Hooke's name functioning as an artistic signature, both highly unusual features for his draughtsmanship. From evidence of how this drawing was collected and physically placed alongside images by leading artists in the early eighteenth century, I suggest how it can offer new insight into the reception of Hooke and his graphic work in the early Enlightenment.
Specificity of the photoreaction of 4'-(hydroxymethyl)-4,5',8-trimethylpsoralen with ribonucleic acid. Identificaton of reactive sites in Escherichia coli phenylalanine-accepting transfer ribonucleic acid
Bachellerie, J.P.; Hearst, J.E.
In order to test the potential of psoralen photo-addition for the probing of RNA conformation at sequence resolution, the specificity of the reaction of 4'-(hydroxymethyl)-4,5',8-trimethylpsoralen (HMT) with Escherichia coli tRNA/sup Phe/ was analyzed. The sites of HMT covalent addition have been identified by a combination of analytical techniques involving chemical cleavage of the tRNA/sup Phe/ molecule at the m/sup 7/G site and gel electrophoresis of RNase T/sub 1/ digests together with paper electrophoretic characterization of HMT-modified nucleotides and oligonucleotides. HMT photoaddition shows a very high preference for uracil residues. However, important differences in HMT photoreactivity are observed for various U sites of the tRNA/sup Phe/ molecule. Reactivity of specific bases has been correlated with partial melting of the molecule. Data available so far indicate a strong preference of the photo-reactive probe for a ''loose'' helical conformation as compared with a tight helix, whereas a random coil appears poorly reactive. (JMT)
Hecht, Lauren N; Cosman, Joshua D; Vecera, Shaun P
Much is known about the cues that determine figure-ground assignment, but less is known about the consequences of figure-ground assignment on later visual processing. Previous work has demonstrated that regions assigned figural status are subjectively more shape-like and salient than background regions. The increase in subjective salience of figural regions could be caused by a number of processes, one of which may be enhanced perceptual processing (e.g., an enhanced neural representation) of figures relative to grounds. We explored this hypothesis by having observers perform a perceptually demanding spatial resolution task in which targets appeared on either figure or ground regions. To rule out a purely attentional account of figural salience, observers discriminated targets on the basis of a region's color (red or green), which was equally likely to define the figure or the ground. The results of our experiments showed that targets appearing on figures were discriminated more accurately than those appearing in ground regions. In addition, targets appearing on figures were discriminated better than those presented in regions considered figurally neutral, but targets appearing within ground regions were discriminated more poorly than those appearing in figurally neutral regions. Taken together, our findings suggest that when two regions share a contour, regions assigned as figure are perceptually enhanced, whereas regions assigned as ground are perceptually suppressed.
Hecht, Lauren N.; Cosman, Joshua D.; Vecera, Shaun P.
Much is known about the cues that determine figure-ground assignment, but less is known about the consequences of figure-ground assignment on later visual processing. Previous work has demonstrated that regions assigned figural status are subjectively more shape-like and salient than background regions. The increase in subjective salience of figural regions could be caused by a number of processes, one of which may be enhanced perceptual processing (e.g., an enhanced neural representation) of figures relative to grounds. We explored this hypothesis by having observers perform a perceptually demanding spatial resolution task in which targets appeared either on figure or ground regions. To rule out a purely attentional account of figural salience, observers discriminated targets on the basis of a region’s color (red or green), which was equally likely to define the figure or the ground. The results of our experiments show that targets appearing on figures were discriminated more accurately than those appearing in ground regions. In addition, targets appearing on figures were discriminated better than those presented in regions considered figurally neutral, but targets appearing within ground regions were discriminated more poorly than those appearing in figurally neutral regions. Taken together, our findings suggest that when two regions share a contour, regions assigned as figure are perceptually enhanced, whereas regions assigned as grounds are perceptually suppressed. PMID:27048441
This on-line document is part of a series, Transportation Facts & Figures, by the Michigan Department of Transportation (MDOT). The Public Transit section of Transportation Facts & Figures cover such topics as intercity bus service, intercity rail se...
This article analyses the ingredients of empire as a pattern of order with geopolitical effects. Noting the imperial form's proclivity for expansion from a critical reading of historical sociology, the article argues that the principal manifestation of earlier geopolitics lay not in the nation...... but in empire. That in turn has been driven by a view of the world as disorderly and open to the ordering will of empires (emanating, at the time of geopolitics' inception, from Europe). One implication is that empires are likely to figure in the geopolitical ordering of the globe at all times, in particular...... after all that has happened in the late twentieth century to undermine nationalism and the national state. Empire is indeed a probable, even for some an attractive form of regime for extending order over the disorder produced by globalisation. Geopolitics articulated in imperial expansion is likely...
Hynes, M.A.; Brooks, P.J.; Van Wyk, J.J.; Lund, P.K.
Previous studies demonstrating the presence of immunoreactive insulin-like growth factors (IGFs) and their receptors in the brain suggest a role of the IGFs in the central nervous system. IGF-II has been implicated as the predominant IGF in brain of mature animals based on studies of immunoreactive peptide and of IGF-II mRNAs. To obtain information about the sites of synthesis of IGF-II in adult rat brain, a 32 P-labeled 31 base long synthetic oligodeoxyribonucleotide complementary in sequence to trailer peptide coding sequences in rat IGF-II mRNA (IGF-II 31 mer) was hybridized with coronal sections of fixed rat brain. The IGF-II 31 mer showed specific hybridization with the choroid plexus throughout rat brain, whereas in other brain regions, structures or cells, hybridization was not discernibly above background. These findings suggest that the choroid plexus is a primary site of synthesis of IGF-II, a probable source of IGF-II in cerebrospinal fluid, and a potential source of IGF-II for actions on target cells within the adult rat brain
Parker, J; Fishman, S E
The structural gene for histidyl-tRNA synthetase was localized to 53.8 min on the Escherichia coli genome. The gene order in this region was determined to be dapE-purC-upp-purG-(guaA, guaB)-hisS-glyA.
Polyribosome aggregation state in growing tissues of barley and wheat leaf of stems of pea and squash was studied in relation to seedling growth and water status of the growing tissue in plants at various levels of osmotic stress. It was found to be highly correlated with water potential and osmotic potential of the growing tissue and with leaf of stem elongation rate. Stress rapidly reduced polyribosome content and water status in growing tissues of barley leaves; changes were slow and slight in the non-growing leaf blade. Membrane-bound and free polyribosomes were equally sensitive to stress-induced disaggregation. Incorporation of 32 PO 4 3- into ribosomal RNA was rapidly inhibited by stress, but stability of poly(A) + RNA relative to ribosomal RNA was similar in stressed and unstressed tissues, with a half-life of about 12 hours. Stress also caused progressive loss of poly(A) + RNA from these tissues. Quantitation of poly(A) and in vitro messenger template activity in polysome gradient fractions showed a shift of activity from the polysomal region to the region of 20-60 S in stressed plants. Messenger RNA in the 20-60 S region coded for the same peptides as mRNA found in the polysomal fraction. Nonpolysomal and polysome-derived messenger ribonucleoprotein complexes (mRNP) were isolated, and characteristic proteins were found associated with either fraction. Polysomal mRNP from stressed or unstressed plants were translated with similar efficiency in a wheat germ cell-free system. It was concluded that no translational inhibitory activity was associated with nonpolysomal mRNP from barley prepared as described
Gertz, B.J.; Gardner, D.G.; Baxter, J.D.
The effect of the glucocorticoid dexamethasone on the production and degradation of rat GH (rGH) cytoplasmic mRNA was studied in cultured rat pituitary tumor (GC) cells. The incorporation of [3H]uridine into both rGH cytoplasmic mRNA and the pyrimidine nucleotide precursor pool was determined in hormone-treated and control cells. From these measurements glucocorticoid effects on absolute production rates of rGH cytoplasmic mRNA were determined and compared to effects on rGH mRNA accumulation. Rat GH mRNA half-life was then calculated based on a first-order decay model. Rat GH mRNA half-life was also directly assayed by: (1) pulse-chase studies and (2) measuring the kinetics of decay of rGH mRNA in cells after transfer from serum-containing to hormone-deficient media. From these independent analyses rGH mRNA half-life estimates ranged from 28-55 h in different experiments. Within individual experiments there was little variability of rGH mRNA decay rates; glucocorticoids were found not to alter the stability of rGH cytoplasmic mRNA. Glucocorticoid induction of rGH cytoplasmic mRNA accumulation was accounted for solely on the basis of increased mRNA production
Brand, R C; Klootwijk, J; Planta, R J; Maden, B E
The biosynthesis of a hypermodified nucleotide, similar to or identical with 3-(3-amino-3-carboxypropyl)-1-methylpseudouridine monophosphate, present in Saccharomyces carlsbergensis 17S and HeLa-cell 18S rRNA, was investigated with respect to the sequence of reactions required for synthesis and their timing in ribosome maturation. In both yeast and HeLa cells methylation precedes attachment of the 3-amino-3-carboxypropyl group. In yeast the methylated precursor nucleotide was tentatively characterized as 1-methylpseudouridine. This precursor nucleotide was demonstrated in both 37S and most of the cytoplasmic 18S pre-rRNA (rRNA precursor) molecules. The synthesis of the hypermodified nucleotide is completed just before the final cleavage of 18S pre-rRNA to give 17S rRNA, so that the final addition of the 3-amino-3-carboxypropyl group is a cytoplasmic event. Comparable experiments with HeLa cells indicated that formation of 1-methylpseudouridine occurs at the level of 45S RNA and addition of the 3-amino-3-carboxypropyl group occurs in the cytoplasm on newly synthesized 18S RNA.
Storgaard, Heidi; Poulsen, Pernille; Ling, Charlotte
-stimulated expressions of GLUT4 were independently and significantly related to whole-body in vivo insulin action, nonoxidative glucose metabolism, and glucose oxidation. CONCLUSION: We show that skeletal muscle GLUT4 gene expression in twins is significantly and independently related to glucose metabolism...
Parker, J; Fishman, S E
The structural gene for histidyl-tRNA synthetase was localized to 53.8 min on the Escherichia coli genome. The gene order in this region was determined to be dapE-purC-upp-purG-(guaA, guaB)-hisS-glyA. PMID:374370
Tanner, N.K.; Hanna, M.M.; Abelson, J.
Yeast tRNA ligase, from Saccharomyces cerevisiae, is one of the protein components that is involved in the splicing reaction of intron-containing yeast precursor tRNAs. It is an unusual protein because it has three distinct catalytic activities. It functions as a polynucleotide kinase, as a cyclic phosphodiesterase, and as an RNA ligase. We have studied the binding interactions between ligase and precursor tRNAs containing two photoreactive uridine analogues, 4-thiouridine and 5-bromouridine. When irradiated with long ultraviolet light, RNA containing these analogues can form specific covalent bonds with associated proteins. In this paper, we show that 4-thiouridine triphosphate and 5-bromouridine triphosphate were readily incorporated into a precursor tRNA(Phe) that was synthesized, in vitro, with bacteriophage T7 RNA polymerase. The analogue-containing precursor tRNAs were authentic substrates for the two splicing enzymes that were tested (endonuclease and ligase), and they formed specific covalent bonds with ligase when they were irradiated with long-wavelength ultraviolet light. We have determined the position of three major cross-links and one minor cross-link on precursor tRNA(Phe) that were located within the intron and near the 3' splice site. On the basis of these data, we present a model for the in vivo splicing reaction of yeast precursor tRNAs
Takahashi, K.; Ghatei, M.A.; Jones, P.M.; Murphy, J.K.; Lam, H.C.; O'Halloran, D.J.; Bloom, S.R.
The presence of immunoreactive (IR) endothelin, endothelin mRNA, and endothelin receptors in human brain and pituitary gland has been studied by RIA, Northern blot hybridization, and receptor assay. IR endothelin was detected in all five brain regions examined (cerebral cortex, cerebellum, brain stem, basal ganglia, and hypothalamus) (6-10 fmol/g wet wt) and spinal cord (22 +/- 6 fmol/g wet wt, n = 7, mean +/- SEM). Higher concentrations of IR endothelin were found in the pituitary gland (147 +/- 30 fmol/g wet wt). Fast protein liquid chromatographic analysis of the IR endothelin in pituitary gland showed a large IR peak in the position of endothelin-3 and a smaller peak in the position of endothelin-1, whereas IR endothelin in the hypothalamus and brain stem was mainly endothelin-1. Endothelin messenger RNA was detected by Northern blot hybridization in the pituitary but not in hypothalamus. The receptor assay showed that 125I-endothelin-1 binding sites were present in large numbers in all five brain regions but were much less abundant in the pituitary gland. Binding capacity and dissociation constant were 5052 +/- 740 fmol/mg protein and 0.045 +/- 0.007 nM in brain stem and 963 +/- 181 fmol/mg protein and 0.034 +/- 0.009 nM in hypothalamus. In the pituitary gland, there were two classes of binding sites for endothelin with dissociation constants of 0.059 +/- 0.002 nM (binding capacity = 418 +/- 63 fmol/mg protein) and 0.652 +/- 0.103 nM (binding capacity = 1717 +/- 200 fmol/mg protein). Endothelin-1, -2 and -3 were almost equipotent in displacing the binding (IC50 approximately 0.04 nM). These findings are in accord with the possibility that endothelin acts as a neurotransmitter, neuromodulator or neurohormone in man
Marie J. Archer
Full Text Available The abundance of mammalian 18S and 28S ribosomal RNA can decrease the detection sensitivity of bacterial or viral targets in complex host-pathogen mixtures. A method to capture human RNA in a single step was developed and characterized to address this issue. For this purpose, capture probes were covalently attached to magnetic microbeads using a dendrimer linker and the solid phase was tested using rat thymus RNA (mammalian components with Escherichia coli RNA (bacterial target as a model system. Our results indicated that random capture probes demonstrated better performance than specific ones presumably by increasing the number of possible binding sites, and the use of a tetrame-thylammonium-chloride (TMA-Cl- based buffer for the hybridization showed a beneficial effect in the selectivity. The subtraction efficiency determined through real-time RT-PCR revealed capture-efficiencies comparable with commercially available enrichment kits. The performance of the solid phase can be further fine tuned by modifying the annealing time and temperature.
Lavranos, T C; Mathis, J M; Latham, S E; Kalionis, B; Shay, J W; Rodgers, R J
We have previously postulated that granulosa cells of developing follicles arise from a population of stem cells. Stem cells and cancer cells can divide indefinitely partly because they express telomerase. Telomerase is a ribonucleoprotein enzyme that repairs the ends of telomeres that otherwise shorten progressively upon each successive cell division. In this study we carried out cell cycle analyses and examined telomerase expression to examine our hypothesis. Preantral (60-100 microm) and small (1 mm) follicles, as well as granulosa cells from medium-sized (3 mm) and large (6-8 mm) follicles, were isolated. Cell cycle analyses and expression of Ki-67, a cell cycle-related protein, were undertaken on follicles of each size (n = 3) by flow cytometry; 12% to 16% of granulosa cells in all follicles were in the S phase, and less than 2% were in the G(2)/M phase. Telomerase activity (n = 3) was highest in the small preantral follicles, declining at the 1-mm stage and even further at the 3-mm stage. In situ hybridization histochemistry was carried out on bovine ovaries, and telomerase RNA was detected in the granulosa cells of growing follicles but not primordial follicles. Two major patterns of staining were observed in the membrana granulosa of antral follicles: staining in the middle and antral layers, and staining in the middle and basal layers. No staining was detected in oocytes. Our results strongly support our hypothesis that granulosa cells arise from a population of stem cells.
Laboureur, Laurent; Guérineau, Vincent; Auxilien, Sylvie; Yoshizawa, Satoko; Touboul, David
A method based on supercritical fluid chromatography coupled to high resolution mass spectrometry for the profiling of canonical and modified nucleosides was optimized, and compared to classical reverse-phase liquid chromatography in terms of separation, number of detected modified nucleosides and sensitivity. Limits of detection and quantification were measured using statistical method and quantifications of twelve nucleosides of a tRNA digest from E. coli are in good agreement with previously reported data. Results highlight the complementarity of both separation techniques to cover the largest view of nucleoside modifications for forthcoming epigenetic studies. Copyright © 2017 Elsevier B.V. All rights reserved.
Pennathur, Subramaniam; Maitra, Dhiman; Byun, Jaeman; Sliskovic, Inga; Abdulhamid, Ibrahim; Saed, Ghassan M.; Diamond, Michael P.; Abu-Soud, Husam M.
Lycopene, a carotenoid found in tomatoes, is a proven anti-oxidant that may lower the risk of certain disorders including heart disease and cancer. Hypochlorous acid (HOCl) is an oxidant linked to tissue oxidation in cardiovascular disease and other inflammatory disorders through its ability to modify proteins, deoxyribonucleic acid, ribonucleic acid and lipids. Here we show that lycopene can function as a potent scavenger of HOCl at a wide range of concentrations that span various pathophysi...
Yu, Hong; Agarwal, Shashank; Johnston, Mark; Cohen, Aaron
Biomedical scientists need to access figures to validate research facts and to formulate or to test novel research hypotheses. However, figures are difficult to comprehend without associated text (e.g., figure legend and other reference text). We are developing automated systems to extract the relevant explanatory information along with figures extracted from full text articles. Such systems could be very useful in improving figure retrieval and in reducing the workload of biomedical scientists, who otherwise have to retrieve and read the entire full-text journal article to determine which figures are relevant to their research. As a crucial step, we studied the importance of associated text in biomedical figure comprehension. Twenty subjects evaluated three figure-text combinations: figure+legend, figure+legend+title+abstract, and figure+full-text. Using a Likert scale, each subject scored each figure+text according to the extent to which the subject thought he/she understood the meaning of the figure and the confidence in providing the assigned score. Additionally, each subject entered a free text summary for each figure-text. We identified missing information using indicator words present within the text summaries. Both the Likert scores and the missing information were statistically analyzed for differences among the figure-text types. We also evaluated the quality of text summaries with the text-summarization evaluation method the ROUGE score. Our results showed statistically significant differences in figure comprehension when varying levels of text were provided. When the full-text article is not available, presenting just the figure+legend left biomedical researchers lacking 39-68% of the information about a figure as compared to having complete figure comprehension; adding the title and abstract improved the situation, but still left biomedical researchers missing 30% of the information. When the full-text article is available, figure comprehension
Full Text Available Aids patients were treated during a year with three different food supplements commercially available: para-pau-aspido (Aspidosperma subincanum Mart. ex A. DC., Apocynaceae; 2Leid (nucleic acids and cytokines; and Para Immuno (propolis, pollen and royal jelly. All foods, given either alone or in combination, proved useful to all AIDS patients who received the supplements, be these under tri-therapy (Triomine: stavudine, lamivudine, névirapine or left unattended.
Full Text Available Figures are ubiquitous in biomedical full-text articles, and they represent important biomedical knowledge. However, the sheer volume of biomedical publications has made it necessary to develop computational approaches for accessing figures. Therefore, we are developing the Biomedical Figure Search engine (http://figuresearch.askHERMES.org to allow bioscientists to access figures efficiently. Since text frequently appears in figures, automatically extracting such text may assist the task of mining information from figures. Little research, however, has been conducted exploring text extraction from biomedical figures.We first evaluated an off-the-shelf Optical Character Recognition (OCR tool on its ability to extract text from figures appearing in biomedical full-text articles. We then developed a Figure Text Extraction Tool (FigTExT to improve the performance of the OCR tool for figure text extraction through the use of three innovative components: image preprocessing, character recognition, and text correction. We first developed image preprocessing to enhance image quality and to improve text localization. Then we adapted the off-the-shelf OCR tool on the improved text localization for character recognition. Finally, we developed and evaluated a novel text correction framework by taking advantage of figure-specific lexicons.The evaluation on 382 figures (9,643 figure texts in total randomly selected from PubMed Central full-text articles shows that FigTExT performed with 84% precision, 98% recall, and 90% F1-score for text localization and with 62.5% precision, 51.0% recall and 56.2% F1-score for figure text extraction. When limiting figure texts to those judged by domain experts to be important content, FigTExT performed with 87.3% precision, 68.8% recall, and 77% F1-score. FigTExT significantly improved the performance of the off-the-shelf OCR tool we used, which on its own performed with 36.6% precision, 19.3% recall, and 25.3% F1-score for
Figure 2. Comparison of the ScHP1 amino acid sequence with H. +. -PPase from other species. The conserved domains GGG,. DVGADLVGKVE, DNVGDNVGD, EYYT and GNTTAA were found in the sequence alignment (shown in red boxes).
According to the latest figures on uranium, soon to be published by the NEA, uranium resources, production and demand are all on the rise. Exploration efforts have increased recently in line with the expected expansion of nuclear energy in the coming years. Total identified resources have grown and are now sufficient to cover 100 years of supply at 2008 rates of consumption. Costs of production have, however, also increased. This article is based on the latest edition of the 'Red Book', Uranium 2009: Resources, Production and Demand, which presents the results of the most recent biennial review of world uranium market fundamentals and a statistical profile of the world uranium industry as of 1 January 2009. It contains official data provided by OECD Nuclear Energy Agency (NEA) and International Atomic Energy Agency (IAEA) member countries on uranium exploration, resources, production and reactor-related requirements. Projections of nuclear generating capacity and reactor-related uranium requirements through 2035 are also provided as well as a discussion of long-term uranium supply and demand issues. Despite recent declines stemming from the global financial crisis, world demand for electricity is expected to continue to grow significantly over the next several decades to meet the needs of an increasing population and economic growth. The recognition by an increasing number of governments that nuclear power can produce competitively priced, base-load electricity that is essentially free of greenhouse gas emissions, coupled with the role that nuclear can play in enhancing security of energy supply, increases the prospects for growth in nuclear generating capacity, although the magnitude of that growth remains to be determined. Regardless of the role that nuclear energy ultimately plays in meeting rising electricity demand, the uranium resource base is more than adequate to meet projected requirements. Meeting even high-case requirements to 2035 would consume less
Carter, E.A.; Hatz, R.A.; Yarmush, M.L.; Tompkins, R.G.
Small intestinal mucosal weight and nutrient absorption are significantly diminished early after cutaneous thermal injuries. Because these intestinal properties are highly dependent on rates of nucleic acid and protein synthesis, in vivo incorporation of thymidine, uridine, and leucine into small intestinal deoxyribonucleic acid, ribonucleic acid, and proteins were measured. Deoxyribonucleic acid synthesis was markedly decreased with the lowest thymidine incorporation in the jejunum (p less than 0.01); these findings were confirmed by autoradiographic identification of radiolabeled nuclei in the intestinal crypts. Protein synthesis was decreased by 6 h postinjury (p less than 0.01) but had returned to normal by 48 h. Consistent with a decreased rate of protein synthesis, ribonucleic acid synthesis was also decreased 18 h postinjury (p less than 0.01). These decreased deoxyribonucleic acid, ribonucleic acid, and protein synthesis rates are not likely a result of ischemia because in other studies of this injury model, intestinal blood flow was not significantly changed by the burn injury. Potentially, factors initiating the acute inflammatory reaction may directly inhibit nucleic acid and protein synthesis and lead to alterations in nutrient absorption and intestinal barrier function after injury
Lazareva, Olga E; Castro, Leyre; Vecera, Shaun P; Wasserman, Edward A
Four pigeons discriminated whether a target spot appeared on a colored figural shape or on a differently colored background by first pecking the target and then reporting its location: on the figure or the background. We recorded three dependent variables: target detection time, choice response time, and choice accuracy. The birds were faster to detect the target, to report its location, and to learn the correct response on figure trials than on background trials. Later tests suggested that the pigeons might have attended to the figural region as a whole rather than using local properties in performing the figure-background discrimination. The location of the figural region did not affect figure-ground assignment. Finally, when 4 other pigeons had to detect and peck the target without making a choice report, no figural advantage emerged in target detection time, suggesting that the birds' attention may not have been automatically summoned to the figural region.
There is an enormous literature on geodetic equilibrium figures, but the various works have not always been interrelated, also for linguistic reasons (English, French, German, Italian, Russian). The author attempts to systematize the various approaches and to use the standard second-order theory for a study of the deviation of the actual earth and of the equipotential reference ellipsoid from an equilibrium figure.
Hoffman, Adria R.
The purpose of this study is to explore smartness and talent as social constructs. Drawing on Holland et al.'s (1998) figured identities, this article explores the figuring of abilities by elucidating the voices of African American high school chorus students. Critical Race Theory (CRT) helps to unpack normalized language and practices that…
Gregg, Melissa K.; Samuel, Arthur G.
Because the environment often includes multiple sounds that overlap in time, listeners must segregate a sound of interest (the auditory figure) from other co-occurring sounds (the unattended auditory ground). We conducted a series of experiments to clarify the principles governing the extraction of auditory figures. We distinguish between auditory…
Bardos, Achilles N.
Responds to previous article (Motta, Little, and Tobin, this issue) which reviewed data-based studies on figure drawings and found little support for their validity or use in assessing personality, behavior, emotion, or intellectual functioning. Notes recent approaches to interpretation of human figure drawings and cites flaws in argument against…
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Balaji Polepalli Ramesh
Full Text Available Biomedical literature incorporates millions of figures, which are a rich and important knowledge resource for biomedical researchers. Scientists need access to the figures and the knowledge they represent in order to validate research findings and to generate new hypotheses. By themselves, these figures are nearly always incomprehensible to both humans and machines and their associated texts are therefore essential for full comprehension. The associated text of a figure, however, is scattered throughout its full-text article and contains redundant information content. In this paper, we report the continued development and evaluation of several figure summarization systems, the FigSum+ systems, that automatically identify associated texts, remove redundant information, and generate a text summary for every figure in an article. Using a set of 94 annotated figures selected from 19 different journals, we conducted an intrinsic evaluation of FigSum+. We evaluate the performance by precision, recall, F1, and ROUGE scores. The best FigSum+ system is based on an unsupervised method, achieving F1 score of 0.66 and ROUGE-1 score of 0.97. The annotated data is available at figshare.com (http://figshare.com/articles/Figure_Associated_Text_Summarization_and_Evaluation/858903.
Polepalli Ramesh, Balaji; Sethi, Ricky J; Yu, Hong
Biomedical literature incorporates millions of figures, which are a rich and important knowledge resource for biomedical researchers. Scientists need access to the figures and the knowledge they represent in order to validate research findings and to generate new hypotheses. By themselves, these figures are nearly always incomprehensible to both humans and machines and their associated texts are therefore essential for full comprehension. The associated text of a figure, however, is scattered throughout its full-text article and contains redundant information content. In this paper, we report the continued development and evaluation of several figure summarization systems, the FigSum+ systems, that automatically identify associated texts, remove redundant information, and generate a text summary for every figure in an article. Using a set of 94 annotated figures selected from 19 different journals, we conducted an intrinsic evaluation of FigSum+. We evaluate the performance by precision, recall, F1, and ROUGE scores. The best FigSum+ system is based on an unsupervised method, achieving F1 score of 0.66 and ROUGE-1 score of 0.97. The annotated data is available at figshare.com (http://figshare.com/articles/Figure_Associated_Text_Summarization_and_Evaluation/858903).
Three figures of merit are proposed as quality measures for surface plasmon waveguides. They are defined as benefit-to-cost ratios where the benefit is confinement and the cost is attenuation. Three different ways of measuring confinement are considered, leading to three figures of merit. One of the figures of merit is connected to the quality factor. The figures of merit were then used to assess and compare the wavelength response of hree popular 1-D surface plasmon waveguides: the single metal-dielectric interface, the metal slab bounded by dielectric and the dielectric slab bounded by metal. Closed form expressions are given for the figures of merit of the single metal-dielectric interface.
Full Text Available In this study, we aim to investigate how students build interaction between concepts and figure in geometry. For this purpose we developed two type data collection tool. First one called shapely is formed eight open ended question which has concepts and figure. Second one called shapeless is formed eight open ended question which has only concepts. To prepare this data collection tools’ difficulty level we took two math teachers’ opinions. Developed data collection tools were applied 120 students at 9th grade and 11th grade in Trabzon Gazi Anatolian High School. First of all we applied shapeless questions. One month later we applied shapely questions. We investigated students’ answer and the data showed that students more succeed in shapely questions than shapeless questions. We concluded that the difficulty of solving shapeless question result from students didn’t manage to draw figure representing concept knowledge or draw wrong figure, figure drawn by students can’t fulfıl generalizability condition and students who have little knowledge of concept in geometry is under the influence of prototype figure.Key Words: Figural concepts theory, geometrical reasoning, geometry teaching
Unrau, P.; Champ, D.R.; Young, J.L.; Grant, C.E.
Holloman reported the isolation from Ustilago maydis of a glycoprotein which prevented the precipitation of nucleic acids in cold 5% trichloroacetic acid. Two glycoprotein fractions from U. maydis with this nucleic acid-solubilizing activity were isolated in our laboratory using improved purification procedures. The activity was not due to nuclease contamination. The glycoproteins are distinguished by: their ability to bind to concanavalin A-Sepharose; their differential binding to double- and single-stranded deoxyribonucleic acid, and to ribonucleic acid; their molecular weights (46,000 and 69,000); and the relative amounts present in growing versus nongrowing cells. Both fractions required sulfhydryl-reducing conditions for optimal yields, specific activity, and stability. Nucleic acid binding was cooperative, the minimum number of glycoproteins required to make a native T7 DNA molecule soluble in dilute acid being estimated at 2 and 15, respectively.
Veronica A. Segarra
Full Text Available As trained scientists, we become adept not only at analyzing and understanding figures in the scientific literature, but also at designing figures to effectively represent our own data and findings. As educators, we strive to pass on these skills to our students, some of whom will ultimately become scientists themselves. Conveying the principles of effective figure design can be challenging, particularly when students have had little exposure to the process of reading scientific literature, much less writing a piece of scientific literature. Improvisational activities in the classroom reinforce teaching goals such as spontaneity, risk-taking, creativity, communication skills, team-building, and critical thinking (2. Indeed, improv training for scientists is becoming more common, helping scientists to communicate more spontaneously about their work and connect with their audience (1. In this article, we present an improvisational game that can aid in the teaching of effective scientific figure design. This “Present-a-Fake-Figure Exercise” is applicable to both the classroom and laboratory settings. In this learning activity, students improvise presenting fake scientific figures to an audience of their peers. These fake figures are prepared beforehand by the instructor and exemplify the do’s and don’ts of scientific figure design. Some of the learning outcomes of the activity include (1 identifying what makes a scientific figure cohesive, easy to analyze, and reader-friendly, and (2 identifying strategies that are useful in the design of a multi-panel figure to convey a scientific story.
Kandil, F I; Fahle, M
Visual figure-ground segregation is achieved by exploiting differences in features such as luminance, colour, motion or presentation time between a figure and its surround. Here we determine the shortest delay times required for figure-ground segregation based on purely temporal features. Previous studies usually employed stimulus onset asynchronies between figure- and ground-containing possible artefacts based on apparent motion cues or on luminance differences. Our stimuli systematically avoid these artefacts by constantly showing 20 x 20 'colons' that flip by 90 degrees around their midpoints at constant time intervals. Colons constituting the background flip in-phase whereas those constituting the target flip with a phase delay. We tested the impact of frequency modulation and phase reduction on target detection. Younger subjects performed well above chance even at temporal delays as short as 13 ms, whilst older subjects required up to three times longer delays in some conditions. Figure-ground segregation can rely on purely temporal delays down to around 10 ms even in the absence of luminance and motion artefacts, indicating a temporal precision of cortical information processing almost an order of magnitude lower than the one required for some models of feature binding in the visual cortex [e.g. Singer, W. (1999), Curr. Opin. Neurobiol., 9, 189-194]. Hence, in our experiment, observers are unable to use temporal stimulus features with the precision required for these models.
Li, Furen; Xie, Xuhui; Tie, Guipeng; Hu, Hao; Zhou, Lin
Currently, ion beam figuring (IBF) technology has presented many excellent performances in figuring potassium dihydrogen phosphate (KDP) crystals, such as it is a noncontact figuring process and it does not require polishing fluid. So, it is a very clean figuring process and does not introduce any impurities. However, the ion beam energy deposited on KDP crystal will heat the KDP crystal and may generate cracks on it. So, it is difficult directly using IBF technology to figure KDP crystal, as oblique incident IBF (OI-IBF) has lower heat deposition, higher removal rate, and smoother surface roughness compared to normal incident IBF. This paper studied the process of using OI-IBF to figure KDP crystal. Removal rates and removal functions at different incident angles were first investigated. Then heat depositions on a test work piece were obtained through experiments. To validate the figuring process, a KDP crystal with a size of 200 mm×200 mm×12 mm was figured by OI-IBF. After three iterations using the OI-IBF process, the surface error decreases from the initial values with PV 1.986λ RMS 0.438λ to PV 0.215λ RMS 0.035λ. Experimental results indicate that OI-IBF is feasible and effective to figure KDP crystals.
Energy in Sweden. Facts and Figures 2005 contains the tabular data for most of the diagrams in the main publication. These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. Facts and Figures is available at www.stem.se in pdf- and excel file formats. With effect from the 2001 edition, statistics are of preliminary character for the two preceding years (2003 and 2004). Breakdowns into certain types of fuels vary somewhat depending on whether preliminary or final data has been used. Further information about the statistics can be found in Energy in Sweden, chapter 8 Energy Facts
Ramachandran, V S; Anstis, S
We explored the relationship between figure-ground segmentation and apparent motion. Results suggest that: static elements in the surround can eliminate apparent motion of a cluster of dots in the centre, but only if the cluster and surround have similar "grain" or texture; outlines that define occluding surfaces are taken into account by the motion mechanism; the brain uses a hierarchy of precedence rules in attributing motion to different segments of the visual scene. Being designated as "figure" confers a high rank in this scheme of priorities.
This paper examines a polyhedral dial from the British Museum made by the instrument maker Ulrich Schniep, and discusses the status of multifunctional scientific instruments. It discerns a multifaceted iconic meaning considering different dimensions such as scientific functionality (astronomy), the complex allegorical figure of Justice (iconography), and the representation of the sovereign (politics), the court and the Kunstkammer of Albrecht v of Bavaria. As a numen mixtum the figure of "Justicia" touches different fields that go far beyond pure astronomical measurement and represents the power of the ruler as well as the rules of economic justice.
This supplement contains the tabular data of most of the diagrams in the main publication (Energy in Sweden 1999, STEM-ET-82-1999). The figures are based on preliminary statistics, and there may be minor differences between similar data in different sections or tables etc. All table headings and notes are given in both Swedish and English
S. van Tuinen (Sjoerd)
textabstractAbstract In his lectures from 1987, Deleuze draws an analogy between Michelangelo‟s figures and Leibnizian substances by claiming that neither are essences but rather sources of modifications or manners of being. The best way to explore this analogy, I argue, is by focusing on
"The Western tradition", as passe-partout, includes fringe figures, émigrés and migrants. Rather than looking to resources at the core of the Western tradition to overcome its own blindnesses, I am more interested in its gaps and peripheries, where other thoughts and renegade knowledges take hold. It is in the contact zones with…
Alexander, Patricia A.; Singer, Lauren M.; Jablansky, Sophie; Hattan, Courtney
This study investigated the relational reasoning capabilities of older adolescents and young adults when the focal assessment was a verbal and more schooled measure than 1 that was figural and more novel in its configuration. To achieve this end, the verbal test of relational reasoning (vTORR) was constructed to parallel the test of relational…
Worldwide figures of photovoltaic power production (in Mw) along 1992 are presented. Worldwide production of modules per manufacturing technology and per manufacturing companies in Europe, USA and Japan are provided as well. The review has used the following sources: ''PV News'', ''PV insider's report'' and ''systems solars''. (Author)
Nagai, Chiyoko; Inui, Toshio; Iwata, Makoto
Williams syndrome (WS) is a neurodevelopmental disorder characterized by severe impairment of visuospatial abilities. Figure-drawing abilities, which are thought to reflect visuospatial abilities, have yet to be fully investigated in WS. The purpose of the present study was to clarify whether drawing abilities differ between WS individuals and…
Yang, Bing; Xie, Xuhui; Li, Furen; Zhou, Lin
The edge effect is regarded as one of the most difficult technical issues for fabricating large primary mirrors, as it can greatly reduce the key performance of the optical system. Ion beam figuring (IBF) has the advantage of no edge effect, so we can use it to remove high points on the edge and improve surface accuracy. The edge local correction method (ELCM) of IBF processes only the surface edge zone, and is very different from the current full caliber figuring method (FCFM). Therefore, it is necessary to study the ELCM of IBF. In this paper, the key factors of ELCM are analyzed, such as dwell time algorithm, edge data extension methods, and the outward dimension of the starting figuring point. At the same time, the distinctions between ELCM and FCFM are compared. Finally, a 142 mm diameter fused silica mirror is fabricated to verify the validity of the theoretical of ELCM. The experimental results indicate that the figuring precision and efficiency can be obviously improved by ELCM.
V. A. Lyakhovetskiy
Full Text Available Subject of Study.The subject of research is the information structure of objects internal representations and operations over them, used by man to solve the problem of mental rotation of figures. To analyze this informational structure we considered not only classical dependencies of the correct answers on the angle of rotation, but also the other dependencies obtained recently in cognitive psychology. Method.The language of technical computing Matlab R2010b was used for developing information model of the mental rotation of figures. Such model parameters as the number of bits in the internal representation, an error probability in a single bit, discrete rotation angle, comparison threshold, and the degree of difference during rotation can be changed. Main Results.The model reproduces qualitatively such psychological dependencies as the linear increase of time of correct answers and the number of errors on the angle of rotation for identical figures, "flat" dependence of the time of correct answers and the number of errors on the angle of rotation for mirror-like figures. The simulation results suggest that mental rotation is an iterative process of finding a match between the two figures, each step of which can lead to a significant distortion of the internal representation of the stored objects. Matching is carried out within the internal representations that have no high invariance to rotation angle. Practical Significance.The results may be useful for understanding the role of learning (including the learning with a teacher in the development of effective information representation and operations on them in artificial intelligence systems.
This book addresses the mathematical rationality contained in the making of string figures. It does so by using interdisciplinary methods borrowed from anthropology, mathematics, history and philosophy of mathematics. The practice of string figure-making has long been carried out in many societies, and particularly in those of oral tradition. It consists in applying a succession of operations to a string (knotted into a loop), mostly using the fingers and sometimes the feet, the wrists or the mouth. This succession of operations is intended to generate a final figure. The book explores differ
Full Text Available Figure skating is a physically demanding sport that requires a unique combination of artistic ability, speed, agility, flexibility and power. During the last decades not only the competitive schedule has become tougher, but after introduction of the new judging system in 2003, also more emphasis is put on difficult technical elements, jumps, steps and spins (ISU Rules, 2006. More studies about possible increasing prevalence of stress fractures in figure skaters and contributing factors are lacking (Dubravcic-Simunjak et al., 2003; Moran, 2000; Pecina et al., 1990. Therefore the aim of this study was to obtain data about the current stress fracture cumulative risk among elite junior and senior figure skaters, as well as possible factors that may contribute to stress fracture incidence. An anonymous questionnaire, divided into 5 sections, inquired about the prevalence of stress fracture were mailed and distributed to all 62 International Skating Union (ISU members by the ISU headquarters in Lausanne, Switzerland. The guidelines of the Helsinki declaration 2004 were followed. From the 644 skaters who received the questionnaire, 412 completed ones were returned from 110 female juniors (78 single skaters, 12 pair skaters and 20 ice dancers and 135 female seniors (97 single skaters, 16 pair skaters and 22 ice dancers and from 79 male juniors (47 single skaters, 12 pair skaters and 20 ice dancers and 88 male seniors (50 single skaters, 16 pair skaters and 22 ice dancers, coming from different ISU members. The response rate was 62% in females and 67% in males. The median age for female skaters was 16 years and for males 18 years (range 12-25 years. All participants started to skate between 3 and 6 years of age and started to compete in national and international competitions when they were between 5 and 7 years old. At the time of this analysis, they had been skating between 9 and 20 years.In females 41 (16.7%, and in males 25 (13.8% figure skaters
It is very difficult to assess the cost of abandoning nuclear energy in France because a lot of relevant figures are not published. The Court of Auditors is due to publish in 2012 a report of the costs of nuclear energy. In the case of nuclear phase out 2 costs have to be considered the dismantling cost and the cost of processing wastes and their disposal. As for the dismantling cost, official assessments in Great-Britain or Germany give a figure around 3 billions pounds per dismantled unit. In France the law imposes to EDF to put by 18 billions euros by 2016 for the future reactor dismantling. Concerning the cost of wastes, it could reach 35 billions euros for dealing with all the radioactive wastes produced till 2030. (A.C.)
Energy in Sweden 2004: Facts and Figures contains the tabular data for most of the diagrams in the main publication. These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. Facts and Figures is available at www.stem.se in pdf- and excel file formats. Since the year 2001 statistics for the period 1983-1998 are revised compared to data for previous editions. With effect from the 2001 edition, statistics are of preliminary character for the two preceding years. Breakdowns into certain types of fuels vary somewhat depending on whether preliminary or final data has been used. Further information about the statistics can be found in Energy in Sweden, chapter 8 Energy Facts.
Takacs, P.Z.; Church, E.L.
Great improvement has been made in the past several years in the quality of optical components used in synchrotron radiation (SR) beamlines. Most of this progress has been the result of vastly improved metrology techniques and instrumentation permitting rapid and accurate measurement of the surface finish and figure on grazing incidence optics. A significant theoretical effort has linked the actual performance of components used as x-ray wavelengths to their topological properties as measured by surface profiling instruments. Next-generation advanced light sources will require optical components and systems to have sub-arc second surface figure tolerances. This paper will explore the consequences of these requirements in terms of manufacturing tolerances to see if the present manufacturing state-of-the-art is capable of producing the required surfaces. 15 refs., 14 figs., 2 tabs
Chapman; Henry N. , Taylor; John S.
A process is provided for producing near-perfect optical surfaces, for EUV and soft-x-ray optics. The method involves polishing or otherwise figuring the multilayer coating that has been deposited on an optical substrate, in order to correct for errors in the figure of the substrate and coating. A method such as ion-beam milling is used to remove material from the multilayer coating by an amount that varies in a specified way across the substrate. The phase of the EUV light that is reflected from the multilayer will be affected by the amount of multilayer material removed, but this effect will be reduced by a factor of 1-n as compared with height variations of the substrate, where n is the average refractive index of the multilayer.
Full Text Available Quality of tourist travel is a relative category, because its success depends on the subjective perception of the personality of tourists on a tourist trip. For this reason, any tourist trip can be treated from the perspective of different types of figurative forms of tourists' personality, which also determine different quality of tourist travel, which, in turn, makes them different. Thus, any tourist trip, unto itself, has its own uniqueness, taking on the forms and content created, for the most part, by the tourists themselves, along with all other tourism stakeholders involved in this process. These forms and contents are primarily conditioned by the spiritual profile of tourists' personality and their psychological and motivational preferences, which is symbolically represented in the figurative context of a chess game. In addition to this, identification of essential characteristics of different spiritual profiles of tourist's personality, must be a starting point for the programming of overall content and especially of animation and cultural content.
Wu, Lixiang; Qiu, Keqiang; Fu, Shaojun
This paper introduces a new scheme of ion beam figuring (IBF), or rather variable-spot IBF, which is conducted at a constant scanning velocity with variable-spot ion beam collimated by a variable diaphragm. It aims at improving the reachability and adaptation of the figuring process within the limits of machine dynamics by varying the ion beam spot size instead of the scanning velocity. In contrast to the dwell time algorithm in the conventional IBF, the variable-spot IBF adopts a new algorithm, which consists of the scan path programming and the trajectory optimization using pattern search. In this algorithm, instead of the dwell time, a new concept, integral etching time, is proposed to interpret the process of variable-spot IBF. We conducted simulations to verify its feasibility and practicality. The simulation results indicate the variable-spot IBF is a promising alternative to the conventional approach.
Full Text Available This article examines authorial performance in the context of DC’s Vertigo line. In the 1990s, Vertigo gained its reputation as an innovative and progressive imprint by promoting the work of British scriptwriters, who were hailed as true author figures, despite the inherently collaborative nature of the mainstream comics industry. In a manner reminiscent of “auteur theory”, writers such as Neil Gaiman, Warren Ellis or Grant Morrison developed attractive author personas which they consistently displayed through interviews, letter columns or social media, but also, more importantly, by inserting their avatars within the comics they scripted. Upon closer examination, however, it becomes clear that their work in fact simultaneously asserts and destabilizes writerly authority, in a manner that is consistent with Linda Hutcheon’s view of postmodernity. By multiplying author figures and playfully disseminating authority, Vertigo authors question their own authorial control over the text, asserting instead the crucial role played by the reader.
Gvozdenović Vasilije P.
Microgenetic analysis was used to investigate perception of illusory contour figures which represent whole, completed forms on the basis of segmented, incomplete stimulation. The analysis provided an experimental approach to this phenomenon which was standardly investigated phenomenologically. Experimental procedure consisted of two phases: a) priming phase and b) test phase which consisted of visual search task. Two types of visual search tasks were applied: (i) classic detection, in which s...
Futtrup Kjær, Jan; Kjær Jacobsen, Christine; Bjerre Herdel, Stine
This NBI Omnichannel Facts and Figures report highlights the central findings from the NBI Omnichannel capability benchmarking tool, based on data collected in 2015 and 2016. The insights shared here provide an understanding of the way companies and marketing departments are working to deliver...... on - and adapt to - the challenges and opportunities related to the customer-centric, omnichannel experience. View this report as a data-freeze and analysis on the status of omnichannel in Denmark as of 2017....
Lavergne, R.; Nanot, B.; Scherrer, S.; Paquel, V.; Louati, S.; Thienard, H.
The consumption of final energy in France in 2006 increased slightly on the whole (+0.6%) and in all sectors except the industry (-0.7%). The final energy consumption is defined as the difference between the total consumption of primary energy and the consumption of the energy production sector. The evolution of the consumption of final energy is different according to the type of energy: +4.1% for coal (due to the strong demand in the iron and steel industry), +3.6% for renewable energies (due to specific development programs), +1.5% for electrical power and no change for oil and natural gas. Despite high prices, sales of car fuels rose by 0.4%, this figure hides the fact that the sales of fuels for diesel cars rose by 2.7% (because of the growing population of diesel cars) while those of grade petrol kept on plummeting (-5.9%). It is important to note that the releases of CO 2 due to energy went down by -1.4% in 2006. The energy bill increased by +18.5% to fetch 46.2*10 9 euros despite the decrease of the imported volumes. This articles details the energy figures for France in 2006 and sheds light particularly on 3 aspects: first, the annual trends in energy since 1973, secondly, the energy bill and thirdly the figures for electricity, natural gas, solid mineral fuels, hydrocarbons and renewable sources of energy. (A.C.)
Nathan J. Antonacci
Full Text Available This three-year study focused on first-year Calculus I students and their abilities to incorporate figures in technical reports. In each year, these calculus students wrote a technical report as part of the Polar Bear Module, an educational unit developed for use in partner courses in biology, computer science, mathematics, and physics as part of the Multidisciplinary Sustainability Education (MSE project at Ithaca College. In the first year of the project, students received basic technical report guidelines. In year two, the report guidelines changed to include explicit language on how to incorporate figures. In year three, a grading rubric was added to the materials provided to one of the two classes. In all three years, the students performed below expectations in their use of graphs in their reports. Reviews of the figures in the 78 technical reports written by the 106 students showed repeated deficiencies in the figures and how the students used them in the discussion sections and in evidence-based arguments. In year three the student’s quantitative literacy (QL skills were assessed using an extract from a QL assessment instrument published in Numeracy. The results indicated that the students could both read and interpret figures, suggesting that issues with QL were not the main contributor to student difficulty with written discussion about graphs. The study underscores the need that explicit instructional attention be given to developing student knowhow in the use of figures in technical reports.
Full Text Available This study aimed to find out the kinds of figurative language in the five selected poetries of Maya Angelou, the titles are: Alone, Caged Bird, Old Folks Laugh, Phenomenal Woman, Still I Rise. The focus of this study is figurative language which involves: Metaphor, Personification, Hyperbole, Simile, Metonymy, Synecdoche, Irony, Antithesis, Symbolism, and Paradox. Qualitative approach with design of content analysis was used in this study. The researcher acted as the main instrument since she was the one who analyzed the figurative language. Moreover checklist was also used to support her data collection. The data was analyzed through three stages; 1. Data reduction, 2. Data representation, 3. Conclusion. The result of her study showed there were 40 sentences that containing figurative language in five selected poetries of Maya Angelou. They were; Metaphor (13 sentences, Personification (9 sentences, Hyperbole (1 sentence, Simile (8 sentences, Synecdoche (1 sentence, Antithesis (1 sentence, Symbolism (5 sentences, and Paradox (2 sentences. The researcher conclude, if the figurative language used by Angelou to compare, or even symbolize the sentences to bring the meaning come up with beautiful language. Mostly of her poetries told about her experience in the past that rooted to history of the discrimination of American-African.
Demmler, Marcel; Zeuner, Michael; Luca, Alfonz; Dunger, Thoralf; Rost, Dirk; Kiontke, Sven; Krüger, Marcus
Silicon lenses are widely used for infrared applications. Especially for portable devices the size and weight of the optical system are very important factors. The use of aspherical silicon lenses instead of spherical silicon lenses results in a significant reduction of weight and size. The manufacture of silicon lenses is more challenging than the manufacture of standard glass lenses. Typically conventional methods like diamond turning, grinding and polishing are used. However, due to the high hardness of silicon, diamond turning is very difficult and requires a lot of experience. To achieve surfaces of a high quality a polishing step is mandatory within the manufacturing process. Nevertheless, the required surface form accuracy cannot be achieved through the use of conventional polishing methods because of the unpredictable behavior of the polishing tools, which leads to an unstable removal rate. To overcome these disadvantages a method called Ion Beam Figuring can be used to manufacture silicon lenses with high surface form accuracies. The general advantage of the Ion Beam Figuring technology is a contactless polishing process without any aging effects of the tool. Due to this an excellent stability of the removal rate without any mechanical surface damage is achieved. The related physical process - called sputtering - can be applied to any material and is therefore also applicable to materials of high hardness like Silicon (SiC, WC). The process is realized through the commercially available ion beam figuring system IonScan 3D. During the process, the substrate is moved in front of a focused broad ion beam. The local milling rate is controlled via a modulated velocity profile, which is calculated specifically for each surface topology in order to mill the material at the associated positions to the target geometry. The authors will present aspherical silicon lenses with very high surface form accuracies compared to conventionally manufactured lenses.
Accumulated evidence for a geometrically and optically thick disk in the β Lyrae system has now established the disk's basic external configuration. Since the disk has been constant in its main properties over the historical interval of β Lyrae observations and also seems to have a basically well-defined photosphere, it is now time to being consideration of its sturcture. Here, we compute equilibrium figures for self-gravitating disks around stars in binary systems as a start toward eventual computation of complete disk models. A key role is played by centrifugally limited rotation of the central star, which would naturally arise late in the rapid phase of mass transfer. Beta Lyrae is thus postulated to be a double-contact binary, which makes possible nonarbitrary separation of star and disk into separate structures. The computed equilibrium figures are three-dimensional, as the gravitation of the second star is included. Under the approximation that the gravitational potential of the disk is that of a thin wire and that the local disk angular velocity is proportional to u/sup n/ (u = distance from rotation axis), we comptue the total potential and locate equipotential surfaces. The centrifugal potential is written in a particularly convenient form which permits one to change the rotation law discontinuously (for example, at the star-disk coupling point) while ensuring that centrifugal potential and centrifigual force are continuous functions of position. With such a one-parameter rotation law, one can find equilibrium disk figures with dimensions very similar to those found in β Lyrae, but considerations of internal consistency demand at least a two-parameter law
Goda, Keisuke; Jalali, Bahram
Amplified dispersive Fourier transformation (ADFT) is a powerful tool for fast real-time spectroscopy as it overcomes the limitations of traditional optical spectrometers. ADFT maps the spectrum of an optical pulse into a temporal waveform using group-velocity dispersion and simultaneously amplifies it in the optical domain. It greatly simplifies spectroscopy by replacing the diffraction grating and detector array in the conventional spectrometer with a dispersive fiber and single-pixel photodetector, enabling ultrafast real-time spectroscopic measurements. Following our earlier work on the theory of ADFT, here we study the effect of noise on ADFT. We derive the noise figure of ADFT and discuss its dependence on various parameters.
Jardetzky, Wenceslas S
Everything in the universe rotates: the meteors, the asteroids, the planets and their satellites, the sun, the stars, the clusters and nebulae, even the galaxies themselves. The problem of the shape of a rotating body is therefore universal in astronomy. Its treatment in this book, which deals with the figures of equilibrium and distortions of rotating bodies, is full and rigorous.Suitable for upper-level undergraduates and graduate students, this text was written by a renowned researcher and educator who taught at Columbia University and served for many years as a research associate at the La
Full Text Available Beside speech, that helps children to express their feelings and experiences, establish relations with people, the drawing is one of the most truthful ways of its expression. In this paper the results of pleasant and unpleasant emotions among children through drawing of human figure are presented. The survey is conducted on 634 children, and the results indicate that there is difference in expressing negative emotions between boys and girls, while at expressing pleasant emotions the results are similar.
This book is composed of chapters that focus specifically on technological developments by distinguished figures in the history of MMS (Mechanism and Machine Science). Biographies of well-known scientists are also included to describe their efforts and experiences, and surveys of their work and achievements, and a modern interpretation of their legacy are presented. After the first two volumes, the papers in this third volume again cover a wide range within the field of the History of Mechanical Engineering with specific focus on MMS and will be of interest and motivation to the work (historical or not) of many.
Catte, M; Cox, M V
The human figure drawings of a group of emotionally-disturbed boys were compared with those of a group of well-adjusted boys closely matched for chronological age and another for mental age. A comparison based on Koppitz's (1968) original emotional indicators and another, based on new UK norms, showed that the emotionally-disturbed children included significantly more indicators in their drawings than their well-adjusted peers. Although this difference was statistically significant it is actually quite small. In addition, there were no differences among the groups in the kinds of indicators they exhibited. The usefulness of the Koppitz test as a tool for clinical use is questioned.
Vecera, Shaun P; Flevaris, Anastasia V; Filapek, Joseph C
In a hierarchical stage account of vision, figure-ground assignment is thought to be completed before the operation of focal spatial attention. Results of previous studies have supported this account by showing that unpredictive, exogenous spatial precues do not influence figure-ground assignment, although voluntary attention can influence figure-ground assignment. However, in these studies, attention was not summoned directly to a region in a figure-ground display. In three experiments, we addressed the relationship between figure-ground assignment and visuospatial attention. In Experiment 1, we replicated the finding that exogenous precues do not influence figure-ground assignment when they direct attention outside of a figure-ground stimulus. In Experiment 2, we demonstrated that exogenous attention can influence figure-ground assignment if it is directed to one of the regions in a figure-ground stimulus. In Experiment 3, we demonstrated that exogenous attention can influence figure-ground assignment in displays that contain a Gestalt figure-ground cue; this result suggests that figure-ground processes are not entirely completed prior to the operation of focal spatial attention. Exogenous spatial attention acts as a cue for figure-ground assignment and can affect the outcome of figure-ground processes.
Pocock, Stuart J; Travison, Thomas G; Wruck, Lisa M
Most clinical trial publications include figures, but there is little guidance on what results should be displayed as figures and how. To evaluate the current use of figures in Trial reports, and to make constructive suggestions for future practice. We surveyed all 77 reports of randomised controlled trials in five general medical journals during November 2006 to January 2007. The numbers and types of figures were determined, and then each Figure was assessed for its style, content, clarity and suitability. As a consequence, guidelines are developed for presenting figures, both in general and for each specific common type of Figure. Most trial reports contained one to three figures, mean 2.3 per article. The four main types were flow diagram, Kaplan Meier plot, Forest plot (for subgroup analyses) and repeated measures over time: these accounted for 92% of all figures published. For each type of figure there is a considerable diversity of practice in both style and content which we illustrate with selected examples of both good and bad practice. Some pointers on what to do, and what to avoid, are derived from our critical evaluation of these articles' use of figures. There is considerable scope for authors to improve their use of figures in clinical trial reports, as regards which figures to choose, their style of presentation and labelling, and their specific content. Particular improvements are needed for the four main types of figures commonly used.
Travison Thomas G
Full Text Available Abstract Background Most clinical trial publications include figures, but there is little guidance on what results should be displayed as figures and how. Purpose To evaluate the current use of figures in Trial reports, and to make constructive suggestions for future practice. Methods We surveyed all 77 reports of randomised controlled trials in five general medical journals during November 2006 to January 2007. The numbers and types of figures were determined, and then each Figure was assessed for its style, content, clarity and suitability. As a consequence, guidelines are developed for presenting figures, both in general and for each specific common type of Figure. Results Most trial reports contained one to three figures, mean 2.3 per article. The four main types were flow diagram, Kaplan Meier plot, Forest plot (for subgroup analyses and repeated measures over time: these accounted for 92% of all figures published. For each type of figure there is a considerable diversity of practice in both style and content which we illustrate with selected examples of both good and bad practice. Some pointers on what to do, and what to avoid, are derived from our critical evaluation of these articles' use of figures. Conclusion There is considerable scope for authors to improve their use of figures in clinical trial reports, as regards which figures to choose, their style of presentation and labelling, and their specific content. Particular improvements are needed for the four main types of figures commonly used.
Baylis, G C; Baylis, L L
Patient CB showed a severe impairment in figure-ground segmentation following a closed head injury. Unlike normal subjects, CB was unable to parse smaller and brighter parts of stimuli as figure. Moreover, she did not show the normal effect that symmetrical regions are seen as figure, although she was able to make overt judgments of symmetry. Since she was able to attend normally to isolated objects, CB demonstrates a dissociation between figure ground segmentation and subsequent processes of attention. Despite her severe impairment in figure-ground segmentation, CB showed normal 'parallel' single feature visual search. This suggests that figure-ground segmentation is dissociable from 'preattentive' processes such as visual search.
Gvozdenović Vasilije P.
Full Text Available Microgenetic analysis was used to investigate perception of illusory contour figures which represent whole, completed forms on the basis of segmented, incomplete stimulation. The analysis provided an experimental approach to this phenomenon which was standardly investigated phenomenologically. Experimental procedure consisted of two phases: a priming phase and b test phase which consisted of visual search task. Two types of visual search tasks were applied: (i classic detection, in which subjects were detecting presence or absence of the target stimuli and (ii two-alternative forced choice, 2AFC, in which subjects performed discrimination between two concurrent targets (target A vs. target B. Variation of exposition of prim stimuli was used as an indication of the percept formation period. Concepts like early vision, visual attention and feature binding were investigated. Four experiments were conducted. Their outcome showed that (i perception of amodal figure requires visual attention, (ii features binding precedes spatial attention and (iii time period of percept formation is dependent of task properties and varies between 50 - 150 ms. Some results obtained in this research could be explained by feature-integration theory (Treisman & Gelade, 1980; Treisman, 1986. Furthermore, percept formation period data comply with data acquired in Elliott & Müller's psychophysical research (1998.
U.S. Environmental Protection Agency — This dataset contains 1) table of bulk Pb-XAS LCF results, 2) table of bulk As-XAS LCF results, 3) figure data of particle size distribution, and 4) figure data for...
Each year EPA releases the Advancing Sustainable Materials Management: Facts and Figures report, formerly called Municipal Solid Waste in the United States: Facts and Figures. It includes information on Municipal Solid Waste generation, recycling, an
Qiu, Fangtu T; Sugihara, Tadashi; von der Heydt, Rüdiger
Attention depends on figure-ground organization: figures draw attention, whereas shapes of the ground tend to be ignored. Recent research has revealed mechanisms for figure-ground organization in the visual cortex, but how these mechanisms relate to the attention process remains unclear. Here we show that the influences of figure-ground organization and volitional (top-down) attention converge in single neurons of area V2 in Macaca mulatta. Although we found assignment of border ownership for attended and for ignored figures, attentional modulation was stronger when the attended figure was located on the neuron's preferred side of border ownership. When the border between two overlapping figures was placed in the receptive field, responses depended on the side of attention, and enhancement was generally found on the neuron's preferred side of border ownership. This correlation suggests that the neural network that creates figure-ground organization also provides the interface for the top-down selection process.
Qiu, Fangtu T.; Sugihara, Tadashi; von der Heydt, Rüdiger
Attention depends on figure-ground organization: figures draw attention, while shapes of the ground tend to be ignored. Recent research has demonstrated mechanisms of figure-ground organization in the visual cortex, but how they relate to the attention process remains unclear. Here we show that the influences of figure-ground organization and volitional (top-down) attention converge in single neurons of area V2. While assignment of border ownership was found for attended as well as for ignore...
Qualified statistical data belong to the instruments of effective association work. Therefore the association, among other activities, carries out statistical investigations on business management among its member enterprises at intervals of two years. This volume contains the results of the business years 1976 and 1977. A main purpose of this statistics is to offer guidelines to the member enterprises, especially figures which allow to compare the evaluated average values of the business with data of the own enterprise, which may be, if necessary, an impetus to think about measures of rationalization. As in former statistics all the results are classified in seven categories that are determined by the size of the enterprise. Compared with the last questionnaire some items have been altered to facilitate the completion. Questions concerning the extent of the public utilities, the structure of the network system and investment planning have been introduced for the first time.
Andrian D. Hagijanto
Full Text Available In order to gain brand awareness effectively%2C advertiser use unusual and sometimes inappropriate form of creatifity to make their ads more memorable such method includes the use of women s sexual attractions which%2C on the other hand%2C causes in fraction of ethical norms. Will this be called a deviations in ads or a compromise approach to the audience taste? Abstract in Bahasa Indonesia : Untuk mencapai brand awareness yang lebih tinggi%2C pengiklan harus membuat iklannya menarik%2C lewat kreativitas yang tinggi. Ketika kreativitas itu menggunakan pendekatan yang terjebak oleh pelanggaran norma-norma etis kemasyarakatan -lewat eksploatasi figur wanita dan daya tarik yang melingkupinya-. Akankah kreativitas itu disebut sebagai penyimpangan dalam iklan? Ataukah sah-sah saja sebagai suatu bentuk pendekatan yang menuruti selera pasar. advertisement%2C women s sexual attractions%2C body language
Is Hitler bigger than Napoleon? Washington bigger than Lincoln? Picasso bigger than Einstein? Quantitative analysts are rapidly finding homes in social and cultural domains, from finance to politics. What about history? In this fascinating book, Steve Skiena and Charles Ward bring quantitative analysis to bear on ranking and comparing historical reputations. They evaluate each person by aggregating the traces of millions of opinions, just as Google ranks webpages. The book includes a technical discussion for readers interested in the details of the methods, but no mathematical or computational background is necessary to understand the rankings or conclusions. Along the way, the authors present the rankings of more than one thousand of history's most significant people in science, politics, entertainment, and all areas of human endeavor. Anyone interested in history or biography can see where their favorite figures place in the grand scheme of things.
Ravn, Signe; Demant, Jakob Johan
(n = 80) in four different parts of Denmark. The interviews included a photo elicitation exercise and the analysis in this article focuses on one particular picture of two young ‘hipster’ men. By using the figure of the hipster as an analytical case, the article illustrates how individual and spatial...... of paying attention to structural inequalities....
Wilson, Brent; Wilson, Marjorie
The purpose of this study is to investigate the interaction of biological unfolding and culturally related factors on sequences of narrative figure drawings by American and Egyptian elementary students. Findings support hypotheses relating to the interaction of natural and nurtural influences on children's drawings. (Author/SJL)
Figure 2. Long PCR products of mitochondrial DNA from the fish T. tor. Lane 1, amplified product using L-12321-Leu and S-LA-16S-H primers. Lane 2, amplified product using H-12321 –Leu and S-LA-16S-L primers. Lane M, 1-Kb DNA ladder. 8 kb ...
Sevaston, G.; Redding, D.; Lau, K.; Breckenridge, W.; Levine, B.; Nerheim, N.; Sirlin, S.; Kadogawa, H.
A system concept for a space based segmented reflector telescope figure control subsystem is described. The concept employs a two phase architecture in which figure initialization and figure maintenance are independent functions. Figure initialization is accomplished by image sharpening using natural reference targets. Figure maintenance is performed by monitoring the relative positions and alignments of the telescope components using an optical truss. Actuation is achieved using precision positioners. Computer simulation results of figure initialization by pairwise segment coalignment/cophasing and simulated annealing are presented along with figure maintenance results using a wavefront error regulation algorithm. Both functions are shown to perform at acceptable levels for the class of submillimeter telescopes that are serving as the focus of this technology development effort. Component breadboard work as well as plans for a system testbed are discussed.
Bartman, R.; Dubovitsky, S.
A sensing and control system is required to maintain high optical figure quality in a segmented reflector. Upon detecting a deviation of the segmented surface from its ideal form, the system drives segment mounted actuators to realign the individual segments and thereby return the surface to its intended figure. When the reflector is in use, a set of figure sensors will determine positions of a number of points on the back surface of each of the reflector's segments, each sensor being assigned to a single point. By measuring the positional deviations of these points from previously established nominal values, the figure sensors provide the control system with the information required to maintain the reflector's optical figure. The optical lever, multiple wavelength interferometer, and electronic capacitive sensor, the most promising technologies for the development of the figure sensor, are illustrated. It is concluded that to select a particular implementation of the figure sensors, performance requirement will be refined and relevant technologies investigated further.
I Gusti Ayu Vina Widiadnya Putri
Full Text Available Language is a highly elaborated signaling system. It serves various functions in communication, it is used to share ideas, convey feelings and emotions, etc. The researchers are interested to uncover more on how people use language in terms of its variety and lexical in one of the popular social media networking platforms that we all know as Facebook. Based on the aforementioned background of the study, the problem of the research can be formulated as follows: (1 what are the figurative languages used in Facebook posts by female and male Facebook users? (2 How are the emotional lexical varieties e.g. used in Facebook posts? Method of research is a procedure needed to do the research better. In this case, method of research covers data source, data collection and data analysis. The data of this research have been taken from Facebook, it is as an online social networking website where people can create profiles, share information such as photos and quotes about themselves, and respond or link to the information posted by others. The method that used in collecting data is method of library research. They are collected by reading the Facebook user’s post, by underlining and note taking as well. The data analysis is the last step in this process of writing this research. The analysis is done by descriptive method. To make the analysis clearer, all of examples are completed with explanation. Referring to the first research problem, there are some figurative languages used by the Facebook users such as, Simile (female 1 or 4.3% and male 0%, Metaphor (female 4 or 17.3% and male 0%,, Personification (female 3 or 1.3% and male 1% or 4.3%,, Hyperbole (female 4 or 17.3% and male 1 or 4.3%, and Idiom (female 3 or 13% and male 0%,. Furthermore, in regards to the second problem that is emotional lexical used by the Facebook Users, we could mention that both the Augmentatives (female 3 or 13% and male 1 or 4.3%, and Euphemisms (female 1 or 4.3% and male 1 or
Liu, N; Ru, Y J; Li, F D; Cowieson, A J
The effect of dietary phytate and phytase on carbohydrase activity and hexose transport was investigated in broiler chickens. Diets containing phytate P (2.2 or 4.4 g/kg) with different phytase dose rates (0, 500, or 1,000 phytase units/kg) were fed to 504 female Cobb chicks for 3 wk. Diets containing high phytate concentrations depressed (P diets containing phytate also decreased (P diets containing increased phytate upregulated (P competence, and phytase can ameliorate these effects for chickens.
BURBACH, JPH; ADAN, RAH; VANTOL, HHM; VERBEECK, MAE; AXELSON, JF; VANLEEUWEN, FW; BEEKMAN, JM; AB, G
Oxytocin (OT) plays a role in reproduction at the level of the pituitary and mammary glands and uterus. This OT is synthesized in the hypothalamo-neurohypophyseal system (HNS). A number of observations have suggested that estrogens regulate the production of OT in the HNS. In this study the effect
Točík, Zdeněk; Krásný, Libor; Kovačková, Soňa; Rejman, Dominik; Rosenberg, Ivan
Roč. 6, č. 5 (2007), s. 357 ISSN 1535-3508. [International Conference of the European Society for Molecular Imaging /2./. 14.06.2007-15.06.2007, Naples] Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50520701 Keywords : UTP derivative * Diels - Alder reaction * diene * spacer arm Subject RIV: CC - Organic Chemistry
Full Text Available Background: Hypocretin (HCRT signaling plays an important role in the pathogenesis of narcolepsy and can be significantly influenced by Chinese herbal therapy. Our previous study showed that xingshentongqiao decoction (XSTQ is clinically effective for the treatment of narcolepsy. To determine whether XSTQ improves narcolepsy by modulating HCRT signaling, we investigated its effects on SH-SY5Y cell proliferation, apoptosis, and HCRT receptor 1/2 (orexin receptor 1 [OX1R] and orexin receptor 2 [OX2R] expression. The signaling pathways involved in these processes were also assessed. Methods: The effects of XSTQ on proliferation and apoptosis in SH-SY5Y cells were assessed using cell counting kit-8 and annexin V-fluorescein isothiocyanate assays. OX1R and OX2R expression was assessed by quantitative real-time polymerase chain reaction analysis. Western blotting for mitogen-activated protein kinase (MAPK pathway activation was performed to further assess the signaling mechanism of XSTQ. Results: XSTQ reduced the proliferation and induced apoptosis of SH-SY5Y cells. This effect was accompanied by the upregulation of OX1R and OX2R expression and the reduced phosphorylation of extracellular signal-regulated kinase (Erk 1/2, p38 MAPK and c-Jun N-terminal kinase (JNK. Conclusions: XSTQ inhibits proliferation and induces apoptosis in SH-SY5Y cells. XSTQ also promotes OX1R and OX2R expression. These effects are associated with the repression of the Erk1/2, p38 MAPK, and JNK signaling pathways. These results define a molecular mechanism for XSTQ in regulating HCRT and MAPK activation, which may explain its ability to treat narcolepsy.
degli Uberti, E.C.; Hanau, S.; Rossi, R.; Piva, R.; Margutti, A.; Trasforini, G.; Pansini, G.; del Senno, L.
The action of somatostatin (SRIH) on 3 H-thymidine (thy) incorporation and on c-myc and thyroglobulin RNA levels in a suspension of follicles from normal and goitrous human thyroid was examined. SRIH, at 10 - 7 M concentration, inhibited basal thy incorporation (maximally by 4 h lasting for up 24 h), which effect was greater in goiter than in normal thyroid and was also detected in growing adherent epithelial cells. Moreover, in a follicle suspension SRIH prevented TSH-stimulated thy incorporation, both in normal and in goitrous thyroid. Basal expression of c-myc RNA was not affected by SRIH in either tissue, whereas the TSH-stimulated c-myc RNA level was significantly reduced in goiter. No effect of SRIH was observed on basal or TSH-stimulated thyroglobulin RNA levels. SRIH did not alter basal cAMP concentrations in normal or goitrous follicles, but it significantly reduced TSH-stimulated cAMP accumulation both in normal thyroid and in goiter. Overall, our data indicate a direct inhibitory action of SRIH on growth, but not on differentiation, of human thyroid, probably by a mechanism not entirely cAMP dependent
Moreno, Renata; Hernández-Arranz, Sofía; La Rosa, Ruggero; Yuste, Luis; Madhushani, Anjana; Shingler, Victoria; Rojo, Fernando
The Crc protein is a global regulator that has a key role in catabolite repression and optimization of metabolism in Pseudomonads. Crc inhibits gene expression post-transcriptionally, preventing translation of mRNAs bearing an AAnAAnAA motif [the catabolite activity (CA) motif] close to the translation start site. Although Crc was initially believed to bind RNA by itself, this idea was recently challenged by results suggesting that a protein co-purifying with Crc, presumably the Hfq protein, could account for the detected RNA-binding activity. Hfq is an abundant protein that has a central role in post-transcriptional gene regulation. Herein, we show that the Pseudomonas putida Hfq protein can recognize the CA motifs of RNAs through its distal face and that Crc facilitates formation of a more stable complex at these targets. Crc was unable to bind RNA in the absence of Hfq. However, pull-down assays showed that Crc and Hfq can form a co-complex with RNA containing a CA motif in vitro. Inactivation of the hfq or the crc gene impaired catabolite repression to a similar extent. We propose that Crc and Hfq cooperate in catabolite repression, probably through forming a stable co-complex with RNAs containing CA motifs to result in inhibition of translation initiation. © 2014 Society for Applied Microbiology and John Wiley & Sons Ltd.
Mezquita, C; Teng, C S
To probe the structural change in the genome of the differentiating germ cell of the maturing rooster testis, the chromatin from nuclei at various stages of differentiation were transcribed with prokaryotic RNA polymerase from Escherichia coli or with eukaryotic RNA polymerase II from wheat germ. The transcription was performed under conditions of blockage of RNA chain reinitiation in vitro with rifampicin or rifampicin AF/013. With the E. coli enzyme, the changes in (1) the titration curve for the enzyme-chromatin interaction, (2) the number of initiation sites, (3) the rate of elongation of RNA chains, and (4) the kinetics of the formation of stable initiation complexes revealed the unmasking of DNA in elongated spermatids and the masking of DNA in spermatozoa. In both cases the stability of the DNA duplex in the initiation region for RNA synthesis greatly increased. In contrast with the E. coli enzyme, the wheat-germ RNA polymerase II was relatively inefficient at transcribing chromatin of elongated spermatids. Such behaviour can be predicted if unmasked double-stranded DNA is present in elongated spermatids. PMID:346018
Liao, S F; Harmon, D L; Vanzant, E S; McLeod, K R; Boling, J A; Matthews, J C
In mammals, the absorption of monosaccharides from small intestinal lumen involves at least 3 sugar transporters (SugT): sodium-dependent glucose transporter 1 (SGLT1; gene SLC5A1) transports glucose and galactose, whereas glucose transporter (GLUT) 5 (GLUT5; gene SLC2A5) transports fructose, across the apical membrane of enterocytes. In contrast, GLUT2 (gene SLC2A2) transports all of these sugars across basolateral and apical membranes. To compare the distribution patterns and sensitivity with nutritional regulation of these 3 SugT mRNA in beef cattle small intestinal tissue, 18 ruminally and abomasally catheterized Angus steers (BW approximately 260 kg) were assigned to water (control), ruminal cornstarch (partially hydrolyzed by alpha-amylase; SH), or abomasal SH infusion treatments (n = 6) and fed an alfalfa-cube-based diet at 1.3 x NE(m) requirement. The SH infusions amounted to 20% of ME intake. After 14- or 16-d of infusion, steers were killed; duodenal, jejunal, and ileal epithelia harvested; and total RNA extracted. The relative amount of SugT mRNA in epithelia was determined using real-time reverse transcription-PCR quantification methods. Basal expression of GLUT2 and SGLT1 mRNA was greater (P content of GLUT5 mRNA was greater (P content of GLUT5 mRNA in small intestinal epithelia was not affected (P > or = 0.16) by either SH infusion treatment. In contrast, GLUT2 and SGLT1 mRNA content in the ileal epithelium was increased (P content also was increased (P = 0.07) by 64% after ruminal SH infusion. These results demonstrate that the ileum of beef cattle small intestine adapts to an increased luminal supply of glucose by increasing SGLT1 and GLUT2 mRNA content, whereas increased ruminal SH supply results in duodenal upregulation of SGLT1 mRNA content. These adaptive responses of GLUT2 and SGLT1 mRNA to abomasal or ruminal SH infusion suggest that beef cattle can adapt to increase their carbohydrate assimilation through small intestinal epithelia, assuming that altered SugT mRNA contents reflect the altered transport functional capacities.
Abu-Halima, Masood; Häusler, Sebastian; Backes, Christina; Fehlmann, Tobias; Staib, Claudia; Nestel, Sigrun; Nazarenko, Irina; Meese, Eckart; Keller, Andreas
MicroRNAs (miRNAs) are class of small RNA molecules with major impact on gene regulation. We analyzed the potential of miRNAs secreted from pre-implantation embryos into the embryonic culture media as biomarkers to predict successful pregnancy. Using microarray analysis, we profiled the miRNome of the 56 spent culture media (SCM) after embryos transfer and found a total of 621 miRNAs in the SCM. On average, we detected 163 miRNAs in SCM of samples with failed pregnancies, but only 149 SCM miRNAs of embryos leading to pregnancies. MiR-634 predicted an embryo transfer leading to a positive pregnancy with an accuracy of 71% and a sensitivity of 85%. Among the 621 miRNAs, 102 (16.4%) showed a differential expression between positive and negative outcome of pregnancy with miR-29c-3p as the most significantly differentially expressed miRNA. The number of extracellular vehicles was lower in SCM with positive outcomes (3.8 × 10 9 /mL EVs), as compared to a negative outcome (7.35 × 10 9 /mL EVs) possibly explaining the reduced number of miRNAs in the SCM associated with failed pregnancies. The analysis of the miRNome in the SCM of couples undergoing fertility treatment lays the ground towards development of biomarkers to predict successful pregnancy and towards understanding the role of embryonic miRNAs found in the SCM.
Conclusions: Cell-free mRNA is an acceptable, easy made, functional test with sensitivity, specificity, PPV and NPV more than Doppler ultrasound for diagnosis and prediction of incidence of placenta accrete and we recommend the use of cell-free mRNA test for diagnosis of placenta accreta.
Cavolina, J. M.; Evans, G. L.; Harris, S. A.; Zhang, M.; Westerlind, K. C.; Turner, R. T.
A 14-day orbital spaceflight was performed using ovariectomized Fisher 344 rats to determine the combined effects of estrogen deficiency and near weightlessness on tibia radial bone growth and cancellous bone turnover. Twelve ovariectomized rats with established cancellous osteopenia were flown aboard the space shuttle Columbia (STS-62). Thirty ovariectomized rats were housed on earth as ground controls: 12 in animal enclosure modules, 12 in vivarium cages, and 6 killed the day of launch for baseline measurements. An additional 18 ovary-intact rats were housed in vivarium cages as ground controls: 8 rats were killed as baseline controls and the remaining 10 rats were killed 14 days later. Ovariectomy increased periosteal bone formation at the tibia-fibula synostosis; cancellous bone resorption and formation in the secondary spongiosa of the proximal tibial metaphysis; and messenger RNA (mRNA) levels for the prepro-alpha2(1) subunit of type 1 collagen, osteocalcin, transforming growth factor-beta, and insulin-like growth factor I in the contralateral proximal tibial metaphysis and for the collagen subunit in periosteum pooled from tibiae and femora and decreased cancellous bone area. Compared to ovariectomized weight-bearing rats, the flight group experienced decreases in periosteal bone formation, collagen subunit mRNA levels, and cancellous bone area. The flight rats had a small decrease in the cancellous mineral apposition rate, but no change in the calculated bone formation rate. Also, spaceflight had no effect on cancellous osteoblast and osteoclast perimeters or on mRNA levels for bone matrix proteins and signaling peptides. On the other hand, spaceflight resulted in an increase in bone resorption, as ascertained from the diminished retention of a preflight fluorochrome label. This latter finding suggests that osteoclast activity was increased. In a follow-up ground-based experiment, unilateral sciatic neurotomy of ovariectomized rats resulted in cancellous bone loss in the unloaded limb in excess of that induced by gonadal hormone deficiency. This additional bone loss was arrested by estrogen replacement. We conclude from these studies that estrogen alters the expression of signaling peptides believed to mediate skeletal adaptation to changes in mechanical usage and likewise modifies the skeletal response to mechanical unloading.
Yoshiga, Daigo; Sato, Naoichi; Torisu, Takehiro; Mori, Hiroyuki; Yoshida, Ryoko; Nakamura, Seiji; Takaesu, Giichi; Kobayashi, Takashi; Yoshimura, Akihiko
Adipocyte differentiation is regulated by insulin and IGF-I, which transmit signals by activating their receptor tyrosine kinase. SH2-B is an adaptor protein containing pleckstrin homology and Src homology 2 (SH2) domains that have been implicated in insulin and IGF-I receptor signaling. In this study, we found a strong link between SH2-B levels and adipogenesis. The fat mass and expression of adipogenic genes including peroxisome proliferator-activated receptor gamma (PPARgamma) were reduced in white adipose tissue of SH2-B-/- mice. Reduced adipocyte differentiation of SH2-B-deficient mouse embryonic fibroblasts (MEFs) was observed in response to insulin and dexamethasone, whereas retroviral SH2-B overexpression enhanced differentiation of 3T3-L1 preadipocytes to adipocytes. SH2-B overexpression enhanced mRNA level of PPARgamma in 3T3-L1 cells, whereas PPARgamma levels were reduced in SH2-B-deficient MEFs in response to insulin. SH2-B-mediated up-regulation of PPARgamma mRNA was blocked by a phosphatidylinositol 3-kinase inhibitor, but not by a MAPK kinase inhibitor. Insulin-induced Akt activation and the phosphorylation of forkhead transcription factor (FKHR/Foxo1), a negative regulator of PPARgamma transcription, were up-regulated by SH2-B overexpression, but reduced in SH2-B-deficient MEFs. These data indicate that SH2-B is a key regulator of adipogenesis both in vivo and in vitro by regulating the insulin/IGF-I receptor-Akt-Foxo1-PPARgamma pathway.
Full Text Available Layback spin is considered as one of the most beautiful and elegant spins performed in figure skating. It is also one of the required spins in competitive short program in female category. Different techniques of executing layback spin with variations in changing the positions of free parts of the body, as well as the evaluation of layback spin in accordance with ISU rules and regulations, which have been used in all International Skating Federation competitions since 2004 (World and European championships, Olympic Games are presented in this paper. Due to very difficult position of the body while performing a layback spin, it is essential that the skaters who want to master it should have excellent agility (especially of the spinal column and shoulder and knee joints and balance. Layback spin performance requires significant skating knowledge, so it cannot be performed by beginners. Depending on the fl exibility and creativity, a skater can execute various positions of the head, arms, body and free leg while performing a layback spin. In some cases, these variations can increase the level of difficulty, and in others only the mark given for executing this spin.
One of the most pressing issues facing the deregulated nuclear electric power industry is its economic competitiveness when compared to other sources of electrical power. Traditionally, finding the optimum loading pattern (LP) that meets all the safety and operational objective functions and at the same time produces the most attractive economical solutions is an iterative process. This is because (a) LP search tools usually lack the capability to generate equilibrium solutions and (b) economics objective functions are hard to include in the search process. In this paper, the Westinghouse Advanced Loading Pattern Search code (ALPS) has been demonstrated to successfully find LPs that meet user-defined operational and safety as well as economics objectives. This has been made possible by the development of TULIP language that allows the integration of external procedures into the search process of the main program, ALPS. In the example given, an economic figure of merit (EFM) has been defined and included via TULIP script into the fuel management optimization problem of a three-loop Westinghouse core operating an 18-month cycle. The LPs found by ALPS exhibit a clear trend of meeting and, in some cases, exceeding the EFM objective function defined for the ALPS search process a priori
Ralph, Brandon C W; Seli, Paul; Cheng, Vivian O Y; Solman, Grayden J F; Smilek, Daniel
We examined how figure-ground segmentation occurs across multiple regions of a visual array during a visual search task. Stimuli consisted of arrays of black-and-white figure-ground images in which roughly half of each image depicted a meaningful object, whereas the other half constituted a less meaningful shape. The colours of the meaningful regions of the targets and distractors were either the same (congruent) or different (incongruent). We found that incongruent targets took longer to locate than congruent targets (Experiments 1, 2, and 3) and that this segmentation-congruency effect decreased when the number of search items was reduced (Experiment 2). Furthermore, an analysis of eye movements revealed that participants spent more time scrutinising the target before confirming its identity on incongruent trials than on congruent trials (Experiment 3). These findings suggest that the distractor context influences target segmentation and detection during visual search. Copyright © 2014 Elsevier B.V. All rights reserved.
Pejin Dušanka J.
Full Text Available Saccharomyces cerevisiae is exposed to different stress factors during the production: osmotic, temperature, oxidative. The response to these stresses is the adaptive mechanism of cells. The raw materials Saccharomyces cerevisiae is produced from, contain metabolism products of present microorganisms and protective agents used during the growth of sugar beet for example the influence of acetic and butyric acid and organochlorinated insecticides, lindan and heptachlor, on the metabolism of Saccharomyces cerevisiae was investigated and presented in this work. The mentioned compounds affect negatively the specific growth rate, yield, content of proteins, phosphorus, total ribonucleic acids. These compounds influence the increase of trechalose and glycogen content in the Saccharomyces cerevisiae cells.
In Norway, improving the efficiency of the hydroelectric grid operation is a stated goal of the Energy Act. Several studies have identified potential profits of such improvement. This publication focuses on costs and improvement potentials. Publication of key figures may stimulate grid owners, boards and administrations to improve the operating efficiency of their grids. The publication shows key figures for the regional- and distribution grid and is based on accounting data for 1994. The key figures are divided into: (1) Cost structure: The key figures express the relative contributions of each cost component to the total income of the grid, (2) Costs and physical quantities: The key figures show the cost of delivering the transport services, (3) Physical quantities: The key figures describe the working conditions of the energy utility. It appears that the cost structure of the sector varies considerably. The same is true of the cost related to the delivery of grid services. 30 figs., 6 tabs
Pinna, Baingio; Reeves, Adam
We report some novel 'lighting' and 'backlighting' effects in plane figures similar to those which induce the 'watercolor illusion', that is, figures made with outlines composed of juxtaposed parallel lines varying in brightness and chromatic color. These new effects show 'illumination' as an emergent percept, and show how arrangements of 'dark and light' along the boundaries of various plane figures model the volume and strengthen the illusion of depth. To account for these various effects we propose several phenomenological 'laws of figurality' to add to the Gestalt laws of organization and figure-ground segregation. We offer a set of meta-laws which are speculative but which serve to integrate and organize the phenomenological laws. These laws indicate how luminance gradient profiles across boundary contours define both the 3D appearance of figures and the properties of the light reflected from their volumetric shapes.
Machado, Joana César; Vacas de Carvalho, Leonor; Torres, Anna; Van de Velden, Michel; Costa, Patrício
Literature concerned with logo strategy suggests that the aesthetic appeal of brand logo significantly influences consumer reactions. The main purpose of this research is to study the influence of the different categories of figurative logo designs on consumer response. Through two studies in three countries, this research sheds light on consumer logo preferences, by investigating the psychological properties of the figurativeness of logo design. Results showed that figurativeness is an essen...
The breath figure method is a versatile and facile approach of generating ordered micro and nanoporous structures in polymeric materials. When a polymer solution (dissolved in a high vapor pressure organic solvent) is evaporated out in the presence of a moist air stream, the evaporative cooling effect causes the condensation and nucleation of water droplets onto the polymer solution surface. This leads to the formation of an imprinted porous structure upon removal of the residual solvent and water. The facile removal of the water droplet template leaving its structural imprint is a specifically appealing aspect of the breath figure film technology. The first part of the dissertation work involves the fabrication of drug loaded breath figure thin films and its utilization as a controlled drug release carrier and biomaterial scaffold. In a single fabrication step, single layer/multilayer porous thin films were designed and developed by combining the breath figure process and a modified spin or dip coating technique. Using biodegradable polymers such as poly (lactic-co-glycolic acid) (PLGA) and poly (ethylene glycol) (PEG), drug loaded films were fabricated onto FDA approved medical devices (the Glaucoma drainage device and the Surgical hernia mesh). The porosity of the films is in the range of 2-4 microm as characterized by scanning electron microscope. The drug coated medical implants were characterized for their surface and bulk morphology, the degradation rate of the film, drug release rate and cell cytotoxicity. The results suggest that the use of breath figure morphologies in biodegradable polymer films adds an additional level of control to drug release. In comparison to non-porous films, the breath figure films showed an increased degradation and enhanced drug release. Furthermore, the porous nature of the film was investigated as a biomaterial scaffold to construct three dimensional in vitro tissue model systems. The breath figure film with interconnected
Compact fluid bodies in equilibrium under its own gravitational field are abundant in the Universe and a proper treatment of them can only be carried out using the full theory of General Relativity. The problem is of enormous complexity as it involves two very different regimes, namely the interior and the exterior of the fluid, coupled through the surface of the body. This problem is very challenging both from a purely theoretical point of view, as well as regarding the obtaining of realistic models and the description of their physical properties. It is therefore an excellent piece of news that the book 'Relativistic Figures of Equilibrium' by R Meinel, M Ansorg, A Kleinwächter, G Neugebauer and D Petroff has been recently published. This book approaches the topic in depth and its contents will be of interest to a wide range of scientists working on gravitation, including theoreticians in general relativity, mathematical physicists, astrophysicists and numerical relativists. This is an advanced book that intends to present some of the present-day results on this topic. The most basic results are presented rather succinctly, and without going into the details, of their derivations. Although primarily not intended to serve as a textbook, the presentation is nevertheless self-contained and can therefore be of interest both for experts on the field as well as for anybody wishing to learn more about rotating self-gravitating compact bodies in equilibrium. It should be remarked, however, that this book makes a rather strong selection of topics and concentrates fundamentally on presenting the main results obtained by the authors during their research in this field. The book starts with a chapter where the fundamental aspects of rotating fluids in equilibrium, including its thermodynamic properties, are summarized. Of particular interest are the so-called mass-shedding limit, which is the limit where the body is rotating so fast that it is on the verge of starting
Araujo Gomes, P.A.M. de.
A method is described which allows to calculate the crystallite orientation distribution in polycrystalline material, from direct pole figures data of its crystallographic planes (Roe's Method). The programme was applied to (1010), (0002), (1011) and (1120) complete pole figures data for a commercial, thin sheet Zircaloy-4 tubing specimen. A semi-automatic Rigaku-Denki texture goniometer, which scans the reciprocal lattice sphere pointwise outputting the data in a punched tape, was used to obtain the pole figures. This is consistent with the results obtained through direct conclusion from the pole figures. (author)
Lamme, Victor A F; Zipser, Karl; Spekreijse, Henk
In a backward masking paradigm, a target stimulus is rapidly (figure-ground segregation can be recorded. Here, we recorded from awake macaque monkeys, engaged in a task where they had to detect figures from background in a pattern backward masking paradigm. We show that the V1 figure-ground signals are selectively and fully suppressed at target-mask intervals that psychophysically result in the target being invisible. Initial response transients, signalling the features that make up the scene, are not affected. As figure-ground modulations depend on feedback from extrastriate areas, these results suggest that masking selectively interrupts the recurrent interactions between V1 and higher visual areas.
Nelson, Rolf A; Palmer, Stephen E
We report five experiments that explore the effect of figure-ground factors on attention. We hypothesized that figural cues, such as familiar shape, would draw attention to the figural side in an attentional cuing task using bipartite figure-ground displays. The first two experiments used faces in profile as the familiar shape and found a perceptual advantage for targets presented on the meaningful side of the central contour in detection speed (Experiment 1) and discrimination accuracy (Experiment 2). The third experiment demonstrated the figural advantage in response time (RT) with nine other familiar shapes (including a sea horse, a guitar, a fir tree, etc.), but only when targets appeared in close proximity to the contour. A fourth experiment obtained a figural advantage in a discrimination task with the larger set of familiar shapes. The final experiment ruled out eye movements as a possible confounding factor by replicating the RT advantage for targets on the figural side of face displays when all trials containing eye movements were eliminated. The results are discussed in terms of ecological influences on attention, and are cast within the framework of Yantis and Jonides's hypothesis that attention is exogenously drawn to the onset of new perceptual objects. We argue that the figural side constitutes an "object" whereas the ground side does not, and that figural cues such as shape familiarity are effective in determining which areas represent objects.
Jeurissen, Danique; Self, Matthew W; Roelfsema, Pieter R
The Differentiation-Integration for Surface Completion (DISC) model aims to explain the reconstruction of visual surfaces. We find the model a valuable contribution to our understanding of figure-ground organization. We point out that, next to border-ownership, neurons in visual cortex code whether surface elements belong to a figure or the background and that this is influenced by attention. We furthermore suggest that there must be strong links between object recognition and figure-ground assignment in order to resolve the status of interior contours. Incorporation of these factors in neurocomputational models will further improve our understanding of surface reconstruction, figure-ground organization, and border-ownership.
U.S. Environmental Protection Agency — Figure summarizes uncertainty (error) in hourly gradient flux measurements by individual analyte. Flux uncertainty is derived from estimates of uncertainty in...
Interactions between ethylene, abscisic acid and cytokinin during germination and seedling establishment in Arabidopsis. VEERAPUTHIRAN SUBBIAH and KARINGU JANARDHAN REDDY. J. Biosci. 35(3), September 2010, 451–459 © Indian Academy of Sciences. Supplementary figure. Supplementary figure 1.
Burgers, C.F.; Konijn, E.A.; Steen, G.J.
Framing is an important concept in communication, yet many framing studies set out to develop frames relevant to only one issue. We expand framing theory by introducing figurative framing. We posit that figurative language types like metaphor, hyperbole and irony are important in shaping public
... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Anatomical Planes 1 Figure 1 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Fig. 1 Figure 1 to Part 1203—Anatomical Planes ER10MR98.001 ...
First page Back Continue Last page Graphics. Figure 1. Associations between pre-ART clinical and laboratory characteristics with subsequent TB-IRIS events. Figure 1. Associations between pre-ART clinical and laboratory characteristics with subsequent TB-IRIS events.
... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Field of Vision 6 Figure 6 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Fig. 6 Figure 6 to Part 1203—Field of Vision ER10MR98.006 ...
Burgers, C.; Konijn, E.A.; Steen, G.J.
Framing is an important concept in communication, yet many framing studies set out to develop frames relevant to only one issue. We expand framing theory by introducing figurative framing. We posit that figurative language types like metaphor, hyperbole and irony are important in shaping public
Pinna, Baingio; Reeves, Adam; Koenderink, Jan; van Doorn, Andrea; Deiana, Katia
The problem of perceptual organization was studied by Gestalt psychologists in terms of figure-ground segregation. In this paper we explore a new principle of figure-ground segregation: accentuation. We demonstrate the effectiveness of accentuation relative to other Gestalt principles, and also
Miura, Yukitoshi; Mori, Masahiro; Matsuda, Toshiaki; Takada, Susumu.
The software for the figure output of JFT-2M experimental data is reported. Since the configuration of a figure is determined by some easy input parameters, then any format of each experimental output is configured freely by this software. (author)
Several examples of solid figures that calculus students can use to exercise their skills at estimating volume are presented. Although these figures are bounded by surfaces that are portions of regular cylinders, it is interesting to note that their volumes can be expressed as rational numbers. (JJK)
Davoodi, Telli; Corriveau, Kathleen H.; Harris, Paul L.
Children in the United States come to distinguish historical from fictional story figures between the ages of 3 and 5 years, guided by the plausibility of the story events surrounding the figure (Corriveau, Kim, Schwalen, & Harris, 2009; Woolley & Cox, 2007). However, U.S. children vary in their reactions to stories that include…
... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Flounder TED 10 Figure 10 to Part 223 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS THREATENED MARINE AND ANADROMOUS SPECIES Pt. 223, Fig. 10 Figure 10 to Part 223—Flounder TED EC01JY91.056 [5...
... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Matagorda TED 3 Figure 3 to Part 223 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS THREATENED MARINE AND ANADROMOUS SPECIES Pt. 223, Fig. 3 Figure 3 to Part 223—Matagorda TED EC01JY91.047 [52...
Motta, Robert W.; And Others
Notes widespread use of human figure drawings to describe and predict psychological functioning. Reviews data-based studies on figure drawings and concludes that there is little support for their validity or for their use as devices to assess personality, behavior, emotion, or intellectual functioning. Presents ease of administration and anecdotal…
Nelson, Rolf; Hebda, Nicholas
In 1923, Adhemar Gelb and Ragnar Granit, two prominent researchers in early Gestalt perceptual theory, reported a lower threshold for detection of a target (a small colored dot) on the ground region of an image than on an adjacent figural region. Although their results had a wide influence on the understanding of figure-ground perception, they are at odds with more recent investigations in which figural regions appear to have a processing advantage over ground regions. The two present studies replicated Gelb and Granit's experiment using a similar figure-ground stimulus albeit with a two-alternative forced choice procedure rather than their original method of adjustment. Experiment 1 found that, contrary to Gelb and Granit's findings, a detection advantage was found for the figural over the ground region. Experiment 2 indicated that explicit contours might have played a role in detection.
Vecera, Shaun P; Vogel, Edward K; Woodman, Geoffrey F
Figure-ground assignment is an important visual process; humans recognize, attend to, and act on figures, not backgrounds. There are many visual cues for figure-ground assignment. A new cue to figure-ground assignment, called lower region, is presented: Regions in the lower portion of a stimulus array appear more figurelike than regions in the upper portion of the display. This phenomenon was explored, and it was demonstrated that the lower-region preference is not influenced by contrast, eye movements, or voluntary spatial attention. It was found that the lower region is defined relative to the stimulus display, linking the lower-region preference to pictorial depth perception cues. The results are discussed in terms of the environmental regularities that this new figure-ground cue may reflect.
Pope-Grattan, M M; Burnett, C N; Wolfe, C V
Seventy-two human figure drawings by forty-three patients who had a diagnosis of Duchenne's muscular dystrophy were examined. The study includes a description of these human figure drawings according to eleven emotional indicators and according to directionality quadrants. When the human figure drawings were used as a projective tool, four personality traits of some of the children were identified: physical inadequacy, immaturity, body anxiety, and insecurity. Both the emotional indicators and the quadrant in which the figures appeared were examined in relation to stages of the disease process to see if the human figure drawings of the children might reflect more stress and anxiety at a particular stage of the disease. Suggestions for improvements and recommendations for future study are given.
We present a computational model that computes and integrates in a nonlocal fashion several configural cues for automatic figure-ground segregation. Our working hypothesis is that the figural status of each pixel is a nonlocal function of several geometric shape properties and it can be estimated without explicitly relying on object boundaries. The methodology is grounded on two elements: multi-directional linear voting and nonlinear diffusion. A first estimation of the figural status of each pixel is obtained as a result of a voting process, in which several differently oriented line-shaped neighborhoods vote to express their belief about the figural status of the pixel. A nonlinear diffusion process is then applied to enforce the coherence of figural status estimates among perceptually homogeneous regions. Computer simulations fit human perception and match the experimental evidence that several cues cooperate in defining figure-ground segregation. The results of this work suggest that figure-ground segregation involves feedback from cells with larger receptive fields in higher visual cortical areas. Copyright © 2015 Elsevier Ltd. All rights reserved.
Kimchi, Ruth; Peterson, Mary A
The question of whether or not figure-ground segmentation can occur without attention is unresolved. Early theorists assumed it can, but the evidence is scant and open to alternative interpretations. Recent research indicating that attention can influence figure-ground segmentation raises the question anew. We examined this issue by asking participants to perform a demanding change-detection task on a small matrix presented on a task-irrelevant scene of alternating regions organized into figures and grounds by convexity. Independently of any change in the matrix, the figure-ground organization of the scene changed or remained the same. Changes in scene organization produced congruency effects on target-change judgments, even though, when probed with surprise questions, participants could report neither the figure-ground status of the region on which the matrix appeared nor any change in that status. When attending to the scene, participants reported figure-ground status and changes to it highly accurately. These results clearly demonstrate that figure-ground segmentation can occur without focal attention.
Tran, Thi Ha Chau; Guyader, Nathalie; Guerin, Anne; Despretz, Pascal; Boucart, Muriel
To investigate impairment in discriminating a figure from its background and to study its relation to visual acuity and lesion size in patients with neovascular age-related macular degeneration (AMD). Seventeen patients with neovascular AMD and visual acuity Figure/ground segregation is impaired in patients with AMD. A white space surrounding an object is sufficient to improve the object's detection and to facilitate figure/ground segregation. These results may have practical applications to the rehabilitation of the environment in patients with AMD.
Energy in Sweden 2009: Facts and figures contains the tabular for most of the diagrams in the main publication (STEM-ET--2009-30). These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. Statistics are of preliminary character for the two last published years (2007 and 2008). Breakdowns into certain types of fuels vary somewhat depending on whether preliminary or final data is used. Please note that the figures have been rounded up or down, therefore totals do not always comply with the sum of individual figures
Peterson, Mary A; Mojica, Andrew J; Salvagio, Elizabeth; Kimchi, Ruth
Nelson and Palmer (2007) concluded that figures/figural properties automatically attract attention, after they found that participants were faster to detect/discriminate targets appearing where a portion of a familiar object was suggested in an otherwise ambiguous display. We investigated whether these effects are truly automatic and whether they generalize to another figural property-convexity. We found that Nelson and Palmer's results do generalize to convexity, but only when participants are uncertain regarding when and where the target will appear. Dependence on uncertainty regarding target location/timing was also observed for familiarity. Thus, although we could replicate and extend Nelson and Palmer's results, our experiments showed that figures do not automatically draw attention. In addition, our research went beyond Nelson and Palmer's, in that we were able to separate figural properties from perceived figures. Because figural properties are regularities that predict where objects lie in the visual field, our results join other evidence that regularities in the environment can attract attention. More generally, our results are consistent with Bayesian theories in which priors are given more weight under conditions of uncertainty.
Impact of enteral supplements enriched with omega-3 fatty acids and/or omega-6 fatty acids, arginine and ribonucleic acid compounds on leptin levels and nutritional status in active Crohn's disease treated with prednisolone
Nielsen, Aneta Aleksandra; Nielsen, Jens Nederby; Grønbaek, Henning
BACKGROUND: Patients with Crohn's disease (CD) often develop malnutrition due to disease activity. We aimed to assess the effect of two different enteral supplements of Impact(R) Powder (IP; Novartis, Switzerland) on leptin levels and nutritional status in active CD patients during prednisolone...... treatment and tapering. METHODS: Thirty-one CD patients were randomized to IP Extra (group 1) or IP Standard (group 2). Leptin levels, nutritional, clinical and biochemical markers were studied at inclusion, after 5 and after 9 weeks of the study. RESULTS: Leptin levels, body mass index (BMI) and total...... to improve nutritional status in CD patients....
Impact of enteral supplements enriched with omega-3 fatty acids and/or omega-6 fatty acids, arginine and ribonucleic acid compounds on leptin levels and nutritional status in active Crohn's disease treated with prednisolone
Nielsen, A.A.; Nielsen, J.N.; Grønbæk, Henning
treatment and tapering. METHODS: Thirty-one CD patients were randomized to IP Extra (group 1) or IP Standard (group 2). Leptin levels, nutritional, clinical and biochemical markers were studied at inclusion, after 5 and after 9 weeks of the study. RESULTS: Leptin levels, body mass index (BMI) and total......BACKGROUND: Patients with Crohn's disease (CD) often develop malnutrition due to disease activity. We aimed to assess the effect of two different enteral supplements of Impact(R) Powder (IP; Novartis, Switzerland) on leptin levels and nutritional status in active CD patients during prednisolone...... cholesterol increased significantly within both groups at week 5 compared to inclusion. Leptin levels correlated with BMI in both groups at inclusion and in group 2 at week 9. In group 1, triglyceride levels remained unchanged, while levels in group 2 increased significantly at week 5 compared to inclusion...
Ferraro, F Richard; Grossman, Jennifer; Bren, Amy; Hoverson, Allysa
An experiment was performed that examined the impact of stimulus orientation on performance on the Rey complex figure. A total of 48 undergraduates (24 men, 24 women) were randomly assigned to one of four Rey figure orientation groups (0 degrees, 90 degrees, 180 degrees, and 270 degrees ). Participants followed standard procedures for the Rey figure, initially copying it in whatever orientation group they were assigned to. Next, all participants performed a 15-20 min lexical decision experiment, used as a filler task. Finally, and unbeknownest to them, participants were asked to recall as much of the figure as they could. As expected, results revealed a main effect of Task (F = 83.92, p orientation was not significant, nor did orientation interact with task (Fs .57). The results are important from an applied setting, especially if testing conditions are less than optimal and a fixed stimulus position is not possible (e.g., testing at the bedside).
U.S. Environmental Protection Agency — Figure summarizes diurnal profiles of uncertainty in the chemical gradient and transfer velocity measurements from which fluxes are calculated. This dataset is...
A report published by the House of Lords Select Committee on Science and Technology, claims that government figures for R&D spending are misleading. They apparently include military projects that are more concerned with product development than original research.
Full Text Available This article proposes a figure ground analogy as alternative way of conceptually integrating sustainability and planning. Within this framework planners are challenged to creatively consider planning practice and thought against a background...
Shiwalkar, Jyoti P.; Deshpande, M. N.
This paper deals with the analysis of cricket match results from the ICC World Cup 2011. We believe that such data provide good material for interesting classroom exercises. (Contains 7 tables and 1 figure.)
Neri, Peter; Levi, Dennis M
The segregation of figure from ground is arguably one of the most fundamental operations in human vision. Neural signals reflecting this operation appear in cortex as early as 50 ms and as late as 300 ms after presentation of a visual stimulus, but it is not known when these signals are used by the brain to construct the percepts of figure and ground. We used psychophysical reverse correlation to identify the temporal window for figure-ground signals in human perception and found it to lie within the range of 100-160 ms. Figure enhancement within this narrow temporal window was transient rather than sustained as may be expected from measurements in single neurons. These psychophysical results prompt and guide further electrophysiological studies.
Humphreys, G W; Müller, H
We report evidence demonstrating that a search asymmetry favoring concave over convex targets can be reversed by altering the figure-ground assignment of edges in shapes. Visual search for a concave target among convex distractors is faster than search for a convex target among concave distractors (a search asymmetry). By using shapes with ambiguous local figure-ground relations, we demonstrated that search can be efficient (with search slopes around 10 ms/item) or inefficient (with search slopes around 30-40 ms/item) with the same stimuli, depending on whether edges are assigned to concave or convex "figures." This assignment process can operate in a top-down manner, according to the task set. The results suggest that attention is allocated to spatial regions following the computation of figure-ground relations in parallel across the elements present. This computation can also be modulated by top-down processes.
Kirchartz, Thomas; Kaienburg, Pascal; Baran, Derya
these criteria considering thermodynamic limits, their correlation to photocurrent and photovoltage, and effects on the fill factor. Each criterion is quantified by a figure of merit (FOM) that directly relates to device performance. To ensure a wide
U.S. Environmental Protection Agency — This file contains three netCDF formatted files containing simulation model results used to produce Figures 6 and 7 and tables 3 and 4. These data can be accessed...
Dalby, J. Thomas; Vale, Helen L.
One hundred and fifteen students in Grade 5 made human figure drawings which were compared with their scores on the Coopersmith Self-esteem Inventory and on teachers' ratings of the students' self-esteem. (Author)
Romeo, August; Arall, Marina; Supèr, Hans
Figure-ground (FG) segmentation is the separation of visual information into background and foreground objects. In the visual cortex, FG responses are observed in the late stimulus response period, when neurons fire in tonic mode, and are accompanied by a switch in cortical state. When such a switch does not occur, FG segmentation fails. Currently, it is not known what happens in the brain on such occasions. A biologically plausible feedforward spiking neuron model was previously devised that performed FG segmentation successfully. After incorporating feedback the FG signal was enhanced, which was accompanied by a change in spiking regime. In a feedforward model neurons respond in a bursting mode whereas in the feedback model neurons fired in tonic mode. It is known that bursts can overcome noise, while tonic firing appears to be much more sensitive to noise. In the present study, we try to elucidate how the presence of noise can impair FG segmentation, and to what extent the feedforward and feedback pathways can overcome noise. We show that noise specifically destroys the feedback enhanced FG segmentation and leaves the feedforward FG segmentation largely intact. Our results predict that noise produces failure in FG perception. PMID:22934028
Machado, J. C.; Vacas-Carvalho, Leonor; Costa, P.; Torres, A.
In a previous investigation, aimed at studying brand identity preferences in a merger context, researchers found the most preferred logos are figurative ones. Additionally, results suggested the aesthetic appeal of the logo significantly influences consumers’ identity choices. These results find support in logo strategy literature. The main purpose of this study is to investigate more thoroughly the influence of logo design characteristics, and particularly of figurativeness, o...
Figure-ground plans show the footprints of buildings and the pattern of unbuilt voids in urban space. Compared historically they reveal the erosion of the public realm over time and provide an analytical basis for tissue repair. The paper traces the communicative power of figure-ground technique to its roots in gestalt psychology, and follows its revival from Colin Rowe’s studio at Cornell through to controversies in post-reunification Berlin. The impact of computerisation is discussed and th...
... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Georgia TED 4 Figure 4 to Part 223 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS THREATENED MARINE AND ANADROMOUS SPECIES Pt. 223, Fig. 4 Figure 4 to Part 223—Georgia TED EC01JY91.048 [52 FR...
Peterson, Mary A; Salvagio, Elizabeth
What are the roles of attention and competition in determining where objects lie in the visual field, a phenomenon known as figure-ground perception? In this chapter, we review evidence that attention and other high-level factors such as familiarity affect figure-ground perception, and we discuss models that implement these effects. Next, we consider the Biased Competition Model of Attention in which attention is used to resolve the competition for neural representation between two nearby stimuli; in this model the response to the stimulus that loses the competition is suppressed. In the remainder of the chapter we discuss recent behavioral evidence that figure-ground perception entails between-object competition in which the response to the shape of the losing competitor is suppressed. We also describe two experiments testing whether more attention is drawn to resolve greater figure-ground competition, as would be expected if the Biased Competition Model of Attention extends to figure-ground perception. In these experiments we find that responses to targets on the location of a losing strong competitor are slowed, consistent with the idea that the location of the losing competitor is suppressed, but responses to targets on the winning competitor are not speeded, which is inconsistent with the hypothesis that attention is used to resolve figure-ground competition. In closing, we discuss evidence that attention can operate by suppression as well as by facilitation.
Full Text Available The phenomenon of the sense of distraction and the feature of figurativeness in it are analysed with the help of phenomenological description, the concept of sense of Juozas Mureika and the conception of imagination of Kristupas Sabolius. The position is followed that the acts of sense and the being of those existing found in them cannot be known in a purely rational way. Knowing is reached with intuitive insights. The experiencing of distraction is approached as one of the norms or intentions of consciousness. The sense of distraction is acknowledged to be a basic value becoming more and more important in a modern stressful life. The article indicates that the intentional beings of the sense of distraction are expressed in really various human activities and are distinguished with mono-subjectivity and unrepeatable feeling. Figurativeness is perceived as the result of imaginary, creative activity of the imagination and aesthetical quality. The peculiarities of the formation of figurativeness are revealed through the phenomenological description of imagination by Sabolius. Four features of the act of visualisation, determining the quality of figurativeness, are emphasized: intentionality, power of transformation, relation with emotions and the symbolism of the image. The conclusion is made that figurativeness, being the result of the creative act (visualisation of imagination, appears as aesthetical quality or the ensemble of qualities. Figurativeness sharpens the sense of distraction and calls the wave of new experiences.
Fowlkes, Charless C; Martin, David R; Malik, Jitendra
Figure-ground organization refers to the visual perception that a contour separating two regions belongs to one of the regions. Recent studies have found neural correlates of figure-ground assignment in V2 as early as 10-25 ms after response onset, providing strong support for the role of local bottom-up processing. How much information about figure-ground assignment is available from locally computed cues? Using a large collection of natural images, in which neighboring regions were assigned a figure-ground relation by human observers, we quantified the extent to which figural regions locally tend to be smaller, more convex, and lie below ground regions. Our results suggest that these Gestalt cues are ecologically valid, and we quantify their relative power. We have also developed a simple bottom-up computational model of figure-ground assignment that takes image contours as input. Using parameters fit to natural image statistics, the model is capable of matching human-level performance when scene context limited.
Tóth, Brigitta; Kocsis, Zsuzsanna; Háden, Gábor P; Szerafin, Ágnes; Shinn-Cunningham, Barbara G; Winkler, István
In everyday acoustic scenes, figure-ground segregation typically requires one to group together sound elements over both time and frequency. Electroencephalogram was recorded while listeners detected repeating tonal complexes composed of a random set of pure tones within stimuli consisting of randomly varying tonal elements. The repeating pattern was perceived as a figure over the randomly changing background. It was found that detection performance improved both as the number of pure tones making up each repeated complex (figure coherence) increased, and as the number of repeated complexes (duration) increased - i.e., detection was easier when either the spectral or temporal structure of the figure was enhanced. Figure detection was accompanied by the elicitation of the object related negativity (ORN) and the P400 event-related potentials (ERPs), which have been previously shown to be evoked by the presence of two concurrent sounds. Both ERP components had generators within and outside of auditory cortex. The amplitudes of the ORN and the P400 increased with both figure coherence and figure duration. However, only the P400 amplitude correlated with detection performance. These results suggest that 1) the ORN and P400 reflect processes involved in detecting the emergence of a new auditory object in the presence of other concurrent auditory objects; 2) the ORN corresponds to the likelihood of the presence of two or more concurrent sound objects, whereas the P400 reflects the perceptual recognition of the presence of multiple auditory objects and/or preparation for reporting the detection of a target object. Copyright © 2016. Published by Elsevier Inc.
Divoli, Anna; Wooldridge, Michael A; Hearst, Marti A
When reading bioscience journal articles, many researchers focus attention on the figures and their captions. This observation led to the development of the BioText literature search engine, a freely available Web-based application that allows biologists to search over the contents of Open Access Journals, and see figures from the articles displayed directly in the search results. This article presents a qualitative assessment of this system in the form of a usability study with 20 biologist participants using and commenting on the system. 19 out of 20 participants expressed a desire to use a bioscience literature search engine that displays articles' figures alongside the full text search results. 15 out of 20 participants said they would use a caption search and figure display interface either frequently or sometimes, while 4 said rarely and 1 said undecided. 10 out of 20 participants said they would use a tool for searching the text of tables and their captions either frequently or sometimes, while 7 said they would use it rarely if at all, 2 said they would never use it, and 1 was undecided. This study found evidence, supporting results of an earlier study, that bioscience literature search systems such as PubMed should show figures from articles alongside search results. It also found evidence that full text and captions should be searched along with the article title, metadata, and abstract. Finally, for a subset of users and information needs, allowing for explicit search within captions for figures and tables is a useful function, but it is not entirely clear how to cleanly integrate this within a more general literature search interface. Such a facility supports Open Access publishing efforts, as it requires access to full text of documents and the lifting of restrictions in order to show figures in the search interface.
Tóth, Brigitta; Kocsis, Zsuzsanna; Háden, Gábor P.; Szerafin, Ágnes; Shinn-Cunningham, Barbara; Winkler, István
In everyday acoustic scenes, figure-ground segregation typically requires one to group together sound elements over both time and frequency. Electroencephalogram was recorded while listeners detected repeating tonal complexes composed of a random set of pure tones within stimuli consisting of randomly varying tonal elements. The repeating pattern was perceived as a figure over the randomly changing background. It was found that detection performance improved both as the number of pure tones making up each repeated complex (figure coherence) increased, and as the number of repeated complexes (duration) increased – i.e., detection was easier when either the spectral or temporal structure of the figure was enhanced. Figure detection was accompanied by the elicitation of the object related negativity (ORN) and the P400 event-related potentials (ERPs), which have been previously shown to be evoked by the presence of two concurrent sounds. Both ERP components had generators within and outside of auditory cortex. The amplitudes of the ORN and the P400 increased with both figure coherence and figure duration. However, only the P400 amplitude correlated with detection performance. These results suggest that 1) the ORN and P400 reflect processes involved in detecting the emergence of a new auditory object in the presence of other concurrent auditory objects; 2) the ORN corresponds to the likelihood of the presence of two or more concurrent sound objects, whereas the P400 reflects the perceptual recognition of the presence of multiple auditory objects and/or preparation for reporting the detection of a target object. PMID:27421185
Full Text Available When reading bioscience journal articles, many researchers focus attention on the figures and their captions. This observation led to the development of the BioText literature search engine, a freely available Web-based application that allows biologists to search over the contents of Open Access Journals, and see figures from the articles displayed directly in the search results. This article presents a qualitative assessment of this system in the form of a usability study with 20 biologist participants using and commenting on the system. 19 out of 20 participants expressed a desire to use a bioscience literature search engine that displays articles' figures alongside the full text search results. 15 out of 20 participants said they would use a caption search and figure display interface either frequently or sometimes, while 4 said rarely and 1 said undecided. 10 out of 20 participants said they would use a tool for searching the text of tables and their captions either frequently or sometimes, while 7 said they would use it rarely if at all, 2 said they would never use it, and 1 was undecided. This study found evidence, supporting results of an earlier study, that bioscience literature search systems such as PubMed should show figures from articles alongside search results. It also found evidence that full text and captions should be searched along with the article title, metadata, and abstract. Finally, for a subset of users and information needs, allowing for explicit search within captions for figures and tables is a useful function, but it is not entirely clear how to cleanly integrate this within a more general literature search interface. Such a facility supports Open Access publishing efforts, as it requires access to full text of documents and the lifting of restrictions in order to show figures in the search interface.
Nath, Chandrani; Kumar, Ashok, E-mail: email@example.com, E-mail: firstname.lastname@example.org [Materials Research Laboratory, Department of Physics, Tezpur University, Tezpur 784 028 (India); Kuo, Yung-Kang [Department of Physics, National Dong-Hwa University, Hualien 974, Taiwan (China); Okram, Gunadhor Singh, E-mail: email@example.com, E-mail: firstname.lastname@example.org [Electrical Transport Laboratory, UGC-DAE Consortium for Scientific Research, University Campus, Khandwa Road, Indore 452 017 (India)
Thermoelectric coolers with figure of merit (ZT) close to unity at low temperatures are the need of the hour with new advances in high temperature superconductors, superconducting microelectronic circuits, quantum computers, and photonics. Here, we demonstrate that the conducting polymer polyaniline (Pani) doped with camphor sulfonic acid synthesized in semi-crystalline nanostructures, possesses a giant Seebeck effect at low temperatures. The resulting enormously large Seebeck coefficient (up to 0.6 V/K) combined with an intrinsically low electrical conductivity and thermal conductivity give rise to a ZT = 0.77 at 45 K and ZT = 2.17 at 17 K.
Full Text Available Hundreds of millions of figures are available in biomedical literature, representing important biomedical experimental evidence. This ever-increasing sheer volume has made it difficult for scientists to effectively and accurately access figures of their interest, the process of which is crucial for validating research facts and for formulating or testing novel research hypotheses. Current figure search applications can't fully meet this challenge as the "bag of figures" assumption doesn't take into account the relationship among figures. In our previous study, hundreds of biomedical researchers have annotated articles in which they serve as corresponding authors. They ranked each figure in their paper based on a figure's importance at their discretion, referred to as "figure ranking". Using this collection of annotated data, we investigated computational approaches to automatically rank figures. We exploited and extended the state-of-the-art listwise learning-to-rank algorithms and developed a new supervised-learning model BioFigRank. The cross-validation results show that BioFigRank yielded the best performance compared with other state-of-the-art computational models, and the greedy feature selection can further boost the ranking performance significantly. Furthermore, we carry out the evaluation by comparing BioFigRank with three-level competitive domain-specific human experts: (1 First Author, (2 Non-Author-In-Domain-Expert who is not the author nor co-author of an article but who works in the same field of the corresponding author of the article, and (3 Non-Author-Out-Domain-Expert who is not the author nor co-author of an article and who may or may not work in the same field of the corresponding author of an article. Our results show that BioFigRank outperforms Non-Author-Out-Domain-Expert and performs as well as Non-Author-In-Domain-Expert. Although BioFigRank underperforms First Author, since most biomedical researchers are either in- or
Liu, Feifan; Yu, Hong
Hundreds of millions of figures are available in biomedical literature, representing important biomedical experimental evidence. This ever-increasing sheer volume has made it difficult for scientists to effectively and accurately access figures of their interest, the process of which is crucial for validating research facts and for formulating or testing novel research hypotheses. Current figure search applications can't fully meet this challenge as the "bag of figures" assumption doesn't take into account the relationship among figures. In our previous study, hundreds of biomedical researchers have annotated articles in which they serve as corresponding authors. They ranked each figure in their paper based on a figure's importance at their discretion, referred to as "figure ranking". Using this collection of annotated data, we investigated computational approaches to automatically rank figures. We exploited and extended the state-of-the-art listwise learning-to-rank algorithms and developed a new supervised-learning model BioFigRank. The cross-validation results show that BioFigRank yielded the best performance compared with other state-of-the-art computational models, and the greedy feature selection can further boost the ranking performance significantly. Furthermore, we carry out the evaluation by comparing BioFigRank with three-level competitive domain-specific human experts: (1) First Author, (2) Non-Author-In-Domain-Expert who is not the author nor co-author of an article but who works in the same field of the corresponding author of the article, and (3) Non-Author-Out-Domain-Expert who is not the author nor co-author of an article and who may or may not work in the same field of the corresponding author of an article. Our results show that BioFigRank outperforms Non-Author-Out-Domain-Expert and performs as well as Non-Author-In-Domain-Expert. Although BioFigRank underperforms First Author, since most biomedical researchers are either in- or out
Peterson, Mary A; Salvagio, Elizabeth
Convexity has long been considered a potent cue as to which of two regions on opposite sides of an edge is the shaped figure. Experiment 1 shows that for a single edge, there is only a weak bias toward seeing the figure on the convex side. Experiments 1-3 show that the bias toward seeing the convex side as figure increases as the number of edges delimiting alternating convex and concave regions increases, provided that the concave regions are homogeneous in color. The results of Experiments 2 and 3 rule out a probability summation explanation for these context effects. Taken together, the results of Experiments 1-3 show that the homogeneity versus heterogeneity of the convex regions is irrelevant. Experiment 4 shows that homogeneity of alternating regions is not sufficient for context effects; a cue that favors the perception of the intervening regions as figures is necessary. Thus homogeneity alone does not alone operate as a background cue. We interpret our results within a model of figure-ground perception in which shape properties on opposite sides of an edge compete for representation and the competitive strength of weak competitors is further reduced when they are homogeneous.
Walters, Mark; Bartlett, Kevin; Brophy, Matthew R.; DeGroote Nelson, Jessica; Medicus, Kate
Sapphire presents many challenges to optical manufacturers due to its high hardness and anisotropic properties. Long lead times and high prices are the typical result of such challenges. The cost of even a simple 'grind and shine' process can be prohibitive. The high precision surfaces required by optical sensor applications further exacerbate the challenge of processing sapphire thereby increasing cost further. Optimax has demonstrated a production process for such windows that delivers over 50% time reduction as compared to traditional manufacturing processes for sapphire, while producing windows with less than 1/5 wave rms figure error. Optimax's sapphire production process achieves significant improvement in cost by implementation of a controlled grinding process to present the best possible surface to the polishing equipment. Following the grinding process is a polishing process taking advantage of chemical interactions between slurry and substrate to deliver excellent removal rates and surface finish. Through experiments, the mechanics of the polishing process were also optimized to produce excellent optical figure. In addition to reducing the cost of producing large sapphire sensor windows, the grinding and polishing technology Optimax has developed aids in producing spherical sapphire components to better figure quality. In addition to reducing the cost of producing large sapphire sensor windows, the grinding and polishing technology Optimax has developed aids in producing spherical sapphire components to better figure quality. Through specially developed polishing slurries, the peak-to-valley figure error of spherical sapphire parts is reduced by over 80%.
Energy in Sweden 2007: Facts and Figures contains the tabular for most of the diagrams in the main publication. These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. 2001 statistics for the period 1983-1999 where revised compared to data for previous editions. With effect from the 2001 edition, statistics are of preliminary character for the two last published years (2005 and 2006). Breakdowns into certain types of fuels vary somewhat depending on whether preliminary or final data is used. Further information about the statistics can be found in Energy in Sweden, chapter 8 Energy Facts. Please note that the figures have been rounded up or down, therefore totals do not always comply with the sum of individual figures
Xiao-fang HUANG; Shou-qian SUN; Ke-jun ZHANG; Tian-ning XU; Jian-feng WU; Bin ZHU
To promote the development of the intangible cultural heritage of the world, shadow play, many studies have focused on shadow puppet modeling and interaction. Most of the shadow puppet figures are still imaginary, spread by ancients, or carved and painted by shadow puppet artists, without consideration of real dimensions or the appearance of human bodies. This study proposes an algorithm to transform 3D human models to 2D puppet figures for shadow puppets, including automatic location of feature points, automatic segmentation of 3D models, automatic extraction of 2D contours, automatic clothes matching, and animation. Experiment proves that more realistic and attractive figures and animations of the shadow puppet can be generated in real time with this algorithm.
Coopersmith, S; Sakai, D; Beardslee, B; Coopersmith, A
Figure drawings were obtained from 97 preadolescent males who differed in self and behavioral assessments of self-esteem. These subjects had been selected from a much larger sample and represented five different types of self-esteem. The figure drawings were scored for 15 variables, dealing with formal characteristics, content, and global-interpretations of the total drawings. Five significant differences were obtained, with the content and global-interpretative categories proving more differentiating between self-esteem groups than did the formal characteristics. Behavioral expressions of self-esteem were more associated with figure drawing characteristics than were subjective evaluations. Discussion focuses on the nature of self-concept and self-esteem in children as a sensorimotor rather than symbolic expression.
Lim, Hui Keow; Slaughter, Virginia
Twenty-nine children with Asperger's syndrome and 28 typically developing children, matched on gender, chronological age and nonverbal IQ, were asked to produce a free drawing, then requested to draw a person, a house and a tree. The drawings were scored using standardized procedures for assessing accuracy, detail and complexity. There were no differences between the diagnostic groups on the tree or house drawing scores. The human figure drawing scores of children with Asperger's syndrome were significantly lower than those of the typically developing children, and there was a positive correlation between human figure drawing scores and communication sub-scores on the Vineland Adaptive Behaviour Scales, for the Asperger's group. These results suggest that the selective deficit in generating human figure representations may derive from a relative lack of interest in the social world, and/or limited practice in drawing people.
In some secondary mathematics curricula, there is a topic called Stereometry that deals with investigating the position and finding the intersection, angle, and distance of lines and planes defined within a prism or pyramid. Coordinate system is not used. The metric tasks are solved using Pythagoras' theorem, trigonometric functions, and sine and cosine rules. The basic problem is to find the section of the figure by a plane that is defined by three points related to the figure. In this article, a formula is derived that gives the positions of the intersection points of such a plane and the figure edges, that is, the vertices of the section polygon. Spreadsheet implementations of the formula for cuboid and right rectangular pyramids are presented. The user can check his/her graphical solution, or proceed if he/she is not able to complete the section.
Schweigert, Wendy A; Cintron, Jennifer; Sullivan, Karin; Ilic, Emily; Ellis, Shannon; Dobrowits, Carrie; Roberts, Crystal
In a series of three studies, characteristics of novel figurative phrases were compared with those of established idioms. Studies 1 and 2 found that certain correlations were found to be strong and in one direction for familiar idioms and comparably strong but in the opposite direction for novel figurative phrases, with the correlations for less familiar idioms usually falling partway between these extremes. Study 2 also noted that written or auditory presentation had minimal effects on characteristic ratings. In Study 3 the correlations among characteristics stayed relatively constant for familiar idioms after one, three, or six presentations, but for the novel figurative phrases, after multiple presentations the correlations changed in the direction of the established idioms.
Segregation of sensory inputs into separate objects is a central aspect of perception and arises in all sensory modalities. The figure-ground segregation problem requires identifying an object of interest in a complex scene, in many cases given binaural auditory or binocular visual observations. The computations required for visual and auditory figure-ground segregation share many common features and can be cast within a unified framework. Sensory perception can be viewed as a problem of optimizing information transmission. Here we suggest a stochastic correlative firing mechanism and an associative learning rule for figure-ground segregation in several classic sensory perception tasks, including the cocktail party problem in binaural hearing, binocular fusion of stereo images, and Gestalt grouping in motion perception.
Gori, Simone; Giora, Enrico; Pedersini, Riccardo
In a series of experiments using ambiguous stimuli, we investigate the effects of displaying ordered, discrete series of images on the dynamics of figure-ground segregation. For low frame presentation speeds, the series were perceived as a sequence of discontinuous, static images, while for high speeds they were perceived as continuous. We conclude that using stimuli varying continuously along one parameter results in stronger hysteresis and reduces spontaneous switching compared to matched static stimuli with discontinuous parameter changes. The additional evidence that the size of the hysteresis effects depended on trial duration is consistent with the stochastic nature of the dynamics governing figure-ground segregation. The results showed that for continuously changing stimuli, alternative figure-ground organizations are resolved via low-level, dynamical competition. A second series of experiments confirmed these results with an ambiguous stimulus based on Petter's effect.
Fang Shaohong; Zhu Zicheng; Zhu Liqun; Ren Yi; Yu Hongmei; Du Chengbao; Xie Guoxue
A new type of 'central display system of figures in fire alarm' includes two parts: (1) software package of drawing picture; (2) real time processing and operate system (POS). Main function of the software package is to draw floor plane figures, fire-fighting facility signs and room numbers; and then all pictures are used in POS. Main functions of POS are to process fire alarm, faults and activation of fire fighting control facility, save and print reports, look over floor plane figures, look over concrete condition of fire fighting facilities, and to show appropriate prompt according to different case. This system realizes many functions, such as, control with mouse, operation with push-button, menu operation interface, flip windows to prompt, and chinese character. It have won acclaim for its amazing interface, its convenience to operate, its reliability and flexibility
Carroll, M K; Ryan-Wenger, N A
The purpose of this study was to identify the fears of school-age children and determine the relationship between fear and anxiety. A descriptive, correlational, secondary analysis study was conducted using a convenience sample of 90 children between the ages of 8 and 12 years. Each child was instructed to complete the Revised Children's Anxiety Scale and then answer questions from a structured interview. On completion, each child was instructed to draw a human figure drawing. Frequency charts and correlational statistics were used to analyze the data. Findings indicated that the most significant fears of the boys were in the categories of animals, safety, school, and supernatural phenomena, whereas girls were more fearful of natural phenomena. High correlations existed between anxiety scores and the number of fears and emotional indicators on human figure drawings. Because human figure drawings are reliable tools for assessing anxiety and fears in children, practitioners should incorporate these drawings as part of their routine assessments of fearful children.
Domenget , Jean-Claude
International audience; L’analyse des figures de l’usager de Twitter représente un enjeu de recherche pour comprendre la construction de ces représentations diverses. L’objectif de cet article est d’analyser la notion d’usager dans le cadre de ce dispositif et d’interroger ses relations avec les notions de public(s), d’audience(s) et de communautés. Les quatre principales figures distinguées (twitto, consommateur, abonné, expert) sont étudiées à partir de deuxcritères majeurs : les principes ...
Skiera, G; Petersen, D; Skalej, M; Fahle, M
We investigated which correlates of figure-ground-segregation can be detected by means of functional magnetic resonance imaging (fMRI). Five subjects were scanned with a Siemens Vision 1.5 T system. Motion, colour, and luminance-defined checkerboards were presented with alternating control conditions containing one of the two features of the checkerboard. We find a segregation-specific activation in V1 for all subjects and all stimuli and conclude that neural mechanisms exist as early as in the primary visual cortex that are sensitive to figure-ground segregation.
The aim of this study is to investigate, analyze and evaluate the mobile phone perceptions of ELT students by the help of figurative language. The participants of this study are Grade 3 and Grade 4 students of ELT Department at Samsun 19 Mayıs University, Faculty of Education, involving 139 students in total. In this research students were asked to use “simile” as a figurative language and complete the sentence “Mobile phone is as ……as…….” in the target language. According to content analys...
After having recalled the different French, European and world objectives in terms of greenhouse gas emission reduction (globally or for different sectors: industry, housing and offices, transport, agriculture), and of renewable energy production and consumption, this document proposes data tables and figures describing the energy consumption evolution in France since 1970 (with respect to sectors as well as with respect to energy sources), the greenhouse gas emission evolution since 1990 and the share of each sector in these emissions. Other tables and figures give a more precise description of the housing sector, of the office buildings sector, of the transportation sector, of the manufacturing industry, and of renewable energies (production capacity, purchase tariffs)
Y A Chudina
Full Text Available Visual recognition features of images with different figure-ground segregation have been considered in the article. The research was carried out within the framework of Sokolov and Izmaylov’s spherical model and was based on the construction of color objects discrimination models depending on the changes of background characteristics. The research has revealed the specific influence of the background on figure discrimination. The derived models reflect the mechanisms of the all-in-one perception of the visual space.
Kinateder, Max; Nelson, Rolf
In 1923, Gelb and Granit, using a method of adjustment for a small red light, reported a lower threshold for the target when presented on a ground region than on an adjacent figural region. More recent work in perceptual organization has found precisely the opposite-a processing advantage seems to go to items presented on the figure, not the ground. Although Gelb and Granit continue to be cited for their finding, it has not previously been available as an English translation. Understanding their methodology and results is important for integrating early Gestalt theory with more recent investigations.
In 1923, Gelb and Granit, using a method of adjustment for a small red light, reported a lower threshold for the target when presented on a ground region than on an adjacent figural region. More recent work in perceptual organization has found precisely the opposite—a processing advantage seems to go to items presented on the figure, not the ground. Although Gelb and Granit continue to be cited for their finding, it has not previously been available as an English translation. Understanding their methodology and results is important for integrating early Gestalt theory with more recent investigations. PMID:28286640
In this guided-inquiry activity, students investigate the ionization of strong and weak acids. Bead models are used to study acid ionization on a particulate level. Students analyze seven strong and weak acid models and make generalizations about the relationship between acid strength and dissociation. (Contains 1 table and 2 figures.)
Cao, Yun; Kim, Hyun-Jin; Li, Ying; Kong, Huimin; Lemieux, Bertrand
Helicase-dependent amplification (HDA) is a novel method for the isothermal in vitro amplification of nucleic acids. The HDA reaction selectively amplifies a target sequence by extension of two oligonucleotide primers. Unlike the polymerase chain reaction (PCR), HDA uses a helicase enzyme to separate the deoxyribonucleic acid (DNA) strands, rather than heat denaturation. This allows DNA amplification without the need for thermal cycling. The helicase used in HDA is a helicase super family II protein obtained from a thermophilic organism, Thermoanaerobacter tengcongensis (TteUvrD). This thermostable helicase is capable of unwinding blunt-end nucleic acid substrates at elevated temperatures (60° to 65°C). The HDA reaction can also be coupled with reverse transcription for ribonucleic acid (RNA) amplification. The products of this reaction can be detected during the reaction using fluorescent probes when incubations are conducted in a fluorimeter. Alternatively, products can be detected after amplification using a disposable amplicon containment device that contains an embedded lateral flow strip. Copyright © 2013 John Wiley & Sons, Inc.
Wickstrom, Megan H.
This article is a report on a teacher study group that focused on three elementary teachers' perceptions of mathematical modeling in contrast to typical mathematics instruction. Through the theoretical lens of figured worlds, I discuss how mathematics instruction was conceptualized across the classrooms in terms of artifacts, discourse, and…
Adler, Peter T.
Human figures drawn by psychiatric patients were evaluated. It was hypothesized that differences in performance, particularly differences reflecting a lower level of cognitive maturity, would be associated with the sociocultural background variables, and that these differences might well be such as to be misinterpreted as psychopathologically…
This article reflects on Genette's most recent work and his theorisation on his own work (its unity and heterogeneity) and the recent multiplication of the areas of study (from music to painting, from Stendhal to Proust). Note is also made of Genette's idiosyncrasy in Figures IV.
Figure summarizes diurnal profiles of uncertainty in the chemical gradient and transfer velocity measurements from which fluxes are calculated. This dataset is associated with the following publication:Rumsey, I. Application of an online ion chromatography-based instrument for gradient flux measurements of speciated nitrogen and sulfur. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 9(6): 2581-2592, (2016).
Universities UK, 2007
This edition of Higher education in facts and figures focusses on Research and innovation. Research and innovation are crucial to the future of the UK's competitiveness. Universities are the prime drivers for this, both through producing, and acting as a magnet for, the best knowledge and talent. The UK's research performance is exceptionally…
Art is a symbolic means of communication through which man can communicate his inner needs, desires and worries. Children find art a good means of communicating what ordinarily, they may not be able to describe orally. This study was on description of Nigerian children human figure art using Lowenfeld and Brittain ...
Figures of Speech are expressions which depart from the acceptable literary sense that are employed to give particular emphasis to an idea or a sentiment in order to beautify a literary work such as poetry and proverbs. These devices occupy an important position in proverbs and they perform functions which make the ...
Tempark, Therdpong; Iwasaki, Julie; Shwayder, Tor
The clinical presentation of arborizing vascular dilatation can resemble Lichtenberg figures from lightning. Both have a feather-like or ferning pattern. We report an interesting case of pressure-induced vasodilatation (PIV) caused by temporary vascular occlusion from jeans buttons. © 2014 Wiley Periodicals, Inc.
Examines the incidence of frightening figures and unhappy endings in traditional and modern Inuit stories and identifies purpose for these elements. Monsters and unhappy endings apparently are tools to help children come to terms with Eskimo environment and values. Studies the conclusions and implications for Indian education. (TES)
Criticizes the recent trend of six-figure-plus salaries for higher education administrators in Canada. Maintains that these salaries reflect neither market value nor individual performance but rather result from aggressive self-promotion and institutional chicanery. Argues that those individuals motivated primarily by money should work in the…
Landman, Rogier; Spekreijse, Henk; Lamme, Victor A F
Partial report methods have shown that a large-capacity representation exists for a few hundred milliseconds after a picture has disappeared. However, change blindness studies indicate that very limited information remains available when a changed version of the image is presented subsequently. What happens to the large-capacity representation? New input after the first image may interfere, but this is likely to depend on the characteristics of the new input. In our first experiment, we show that a display containing homogeneous image elements between changing images does not render the large-capacity representation unavailable. Interference occurs when these new elements define objects. On that basis we introduce a new method to produce change blindness: The second experiment shows that change blindness can be induced by redefining figure and background, without an interval between the displays. The local features (line segments) that defined figures and background were swapped, while the contours of the figures remained where they were. Normally, changes are easily detected when there is no interval. However, our paradigm results in massive change blindness. We propose that in a change blindness experiment, there is a large-capacity representation of the original image when it is followed by a homogeneous interval display, but that change blindness occurs whenever the changed image forces resegregation of figures from the background.
Lamme, V.A.F.; Roelfsema, P.R.; Spekreijse, H.; Bosch, H.
Proposes a model of how the visual brain segregate textured scenes into figures and background. During texture segregation, locations where the properties of texture elements change abruptly are assigned to boundaries, whereas image regions that are relatively homogeneous are grouped together
Roelfsema, Pieter R.; Lamme, Victor A. F.; Spekreijse, Henk; Bosch, Holger
Here we propose a model of how the visual brain segregates textured scenes into figures and background. During texture segregation, locations where the properties of texture elements change abruptly are assigned to boundaries, whereas image regions that are relatively homogeneous are grouped
Mulcahy, T.H.; He, Jianliang; Rote, D.M.; Rossing, T.D.
For the first time, the lift, drag, and guidance forces acting on a permanent magnet are measured as the magnet passes over different arrays of figure-eight (null-flux) coils. The experimental results are in good agreement with the predictions of dynamic circuit theory, which is used to explain more optimal coil arrays
Macias B, L.R
The objective of this work, is that starting from a data file coming from a spectra that has been softened, and of the one that have been generated its coordinates to project it in stereographic form, to create the corresponding polar figure making use of the Cyber computer of the ININ by means of the GRAPHOS package. This work only requires a Beta, Fi and Intensity (I) enter data file. It starts of the existence of a softened spectra of which have been generated already with these data, making use of some language that in this case was FORTRAN for the Cyber computer, a program is generated supported in the Graphos package that allows starting of a reading of the Beta, Fi, I file, to generate the points in a stereographic projection and that it culminates with the graph of the corresponding polar figure. The program will request the pertinent information that is wanted to capture in the polar figure just as: date, name of the enter file, indexes of the polar figure, number of levels, radio of the stereographic projection (cms.), crystalline system to which belongs the sample, name the neuter graph file by create and to add the own general data. (Author)
Gailly, P.; Collette, J.-P.; Fleury Frenette, K.; Jamar, C.
Optical and structural elements made of silicon carbide are increasingly found in space instruments. Chemical vapor deposited silicon carbide (CVD-SiC) is used as a reflective coating on SiC optics in reason of its good behavior under polishing. The advantage of applying ion beam figuring (IBF) to CVD-SiC over other surface figure-improving techniques is discussed herein. The results of an IBF sequence performed at the Centre Spatial de Liège on a 100 mm CVD-SiC mirror are reported. The process allowed to reduce the mirror surface errors from 243 nm to 13 nm rms . Beside the surface figure, roughness is another critical feature to consider in order to preserve the optical quality of CVD-SiC . Thus, experiments focusing on the evolution of roughness were performed in various ion beam etching conditions. The roughness of samples etched at different depths down to 3 ≠m was determined with an optical profilometer. These measurements emphasize the importance of selecting the right combination of gas and beam energy to keep roughness at a low level. Kaufman-type ion sources are generally used to perform IBF but the performance of an end-Hall ion source in figuring CVD-SiC mirrors was also evaluated in this study. In order to do so, ion beam etching profiles obtained with the end-Hall source on CVD-SiC were measured and used as a basis for IBF simulations.
commending or reproving the person or thing to which it is applied, and often containing some ... association or the comparison of two things. 2. Figures of ..... to absorb the club while the peacemaker says he is as hard (difficult) as a piece of ...
Figuring the Past geeft een nieuwe kijk op kostuumdrama's die aan het begin van deze eeuw gemaakt zijn en onderzoekt de manieren waarop de hedendaagse cinema het historische verleden herschept. De auteur verkent de relatie tussen visuele motieven en culturele representaties in een aantal belangrijke
... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Test Frame 2 Figure 2 to Subpart A of Part 1201 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS... Subpart A of Part 1201—Test Frame EC03OC91.005 ...
Peterson, Mary A.; Skow, Emily
Theories of figure-ground perception entail inhibitory competition between either low-level units (edge or feature units) or high-level shape properties. Extant computational models instantiate the 1st type of theory. The authors investigated a prediction of the 2nd type of theory: that shape properties suggested on the ground side of an edge are…
Domijan, Drazen; Setić, Mia
A computational model is proposed in order to explain how bottom-up and top-down signals are combined into a unified perception of figure and background. The model is based on the interaction between the ventral and the dorsal stream. The dorsal stream computes saliency based on boundary signals provided by the simple and the complex cortical cells. Output from the dorsal stream is projected to the surface network which serves as a blackboard on which the surface representation is formed. The surface network is a recurrent network which segregates different surfaces by assigning different firing rates to them. The figure is labeled by the maximal firing rate. Computer simulations showed that the model correctly assigns figural status to the surface with a smaller size, a greater contrast, convexity, surroundedness, horizontal-vertical orientation and a higher spatial frequency content. The simple gradient of activity in the dorsal stream enables the simulation of the new principles of the lower region and the top-bottom polarity. The model also explains how the exogenous attention and the endogenous attention may reverse the figural assignment. Due to the local excitation in the surface network, neural activity at the cued region will spread over the whole surface representation. Therefore, the model implements the object-based attentional selection.
Jeurissen, D.; Self, M.W.; Roelfsema, P.R.
The Differentiation-Integration for Surface Completion (DISC) model aims to explain the reconstruction of visual surfaces. We find the model a valuable contribution to our understanding of figure-ground organization. We point out that, next to border-ownership, neurons in visual cortex code whether
Jeurissen, Danique; Self, Matthew W.; Roelfsema, Pieter R.
Abstract The Differentiation-Integration for Surface Completion (DISC) model aims to explain the reconstruction of visual surfaces. We find the model a valuable contribution to our understanding of figure-ground organization. We point out that, next to border-ownership, neurons in visual cortex code
Objective: The current study sought to explore body figure preference in a cross cultural South African sample, given the established relationship between body dissatisfaction and eating disorders. Methods: The sample comprised a community based, multi-racial adolescent population in both urban (n=1353) and rural ...
This supplement contains the tabular data of most of the diagrams in the main publication (Energy in Sweden 1999, STEM-ET-82-1999). The figures are based on preliminary statistics, and there may be minor differences between similar data in different sections or tables etc. All table headings and notes are given in both Swedish and English.
Han, Julie S; Geminiani, Ellen T; Micheli, Lyle J
As the popularity and technical demands of figure skating increase, so will the number of athletes presenting with sport-related problems. Searches were performed across PubMed from 1980 to 2017. The keywords searched were skating, skaters, incidence, and injuries. The search was limited to English-language articles and human participants. Relevant articles were cross-referenced. Clinical review. Level 5. Previous studies suggest an increase in incidence of figure skating injuries from 1982 to 2003. When combining all disciplines of figure skating, there is a similar proportion of acute and overuse injuries. Within disciplines, overuse injuries appear to be more common in singles skating, while acute injuries are more common in pairs skating, ice dancing, and synchronized skating. Lower extremity injuries are more common than upper extremity injuries in all disciplines, and pairs skating accounts for the majority of upper extremity injuries. Ankle sprains are the most common skating injury, and patellar tendinitis is the most common overuse injury across all disciplines. Stress fractures are the most common overuse injury in female singles skaters. The predominance of overuse injuries in singles disciplines reflects their increasing technical difficulty, with more difficult jumps and longer training hours. Partner disciplines are more likely to involve acute injuries and upper extremity injuries due to high-risk throws and lifts. Emphasis should be placed on properly fitting skating boots, intrinsic foot and ankle strengthening, and lower extremity flexibility, which may prevent many of the common lower extremity and back injuries in figure skating.
Looney, Marilyn A.
The purpose of this study was to determine if the 2010 Olympic figure skating judges had trouble scoring Plushenko and the transitions program component, and if the International Skating Union's (ISU) "corridor" method flagged the same judging anomalies as the Rasch analyses. A 3-facet (skater by program component by judge) Rasch rating…
Calculations are given to show that for low thermal conductivity materials the radiation losses at even moderate temperatures preclude the use of the Harman technique for measuring the thermoelectric figure of merit. Measurements on liquid Tl 66 Se 34 , which has suitable thermoelectric properties, confirm this. (author)
Coopersmith, Stanley; And Others
Results of the study show that several features of figure drawing identify the children who differ in self esteem. These differentiating features are associated with behavioral expressions of esteem rather than with self-appraisals of personal worth. (Author/DEP)
the PMR for the black population is considerably hi9her than for the other ethnic groups. That said, perinatal mortality levels in South African blacks still compare favourably with figures from other African cQuntries.12. In conclusion, the MMRs and PMRs found in our survey of. 249 South African hospitals - though not truly.
Data on 2003 – 2005 cattle and goats slaughter figures for Rivers State was obtained from the meat inspection records of the Department of Veterinary Services, Rivers State Ministry of Agriculture, Port Harcourt. Total number of cattle and goats inspected and slaughtered at Rumueme slaughter slab, in Port Harcourt ...
Full Text Available Abstract Background Figure rating scales were developed as a tool to determine body dissatisfaction in women, men, and children. However, it lacks in the literature the validation of the scale for body silhouettes previously adapted. We aimed to obtain evidence for construct validity of a figure rating scale for Brazilian adolescents. Methods The study was carried out with adolescent students attending three public schools in an urban region of the municipality of Florianopolis in the State of Santa Catarina (SC. The sample comprised 232 10-19-year-old students, 106 of whom are boys and 126 girls, from the 5th "series" (i.e. year of Primary School to the 3rd year of Secondary School. Data-gathering involved the application of an instrument containing 8 body figure drawings representing a range of children's and adolescents' body shapes, ranging from very slim (contour 1 to obese (contour 8. Weights and heights were also collected, and body mass index (BMI was calculated later. BMI was analyzed as a continuous variable, using z-scores, and as a dichotomous categorical variable, representing a diagnosis of nutritional status (normal and overweight including obesity. Results Results showed that both males and females with larger BMI z-scores chose larger body contours. Girls with higher BMI z-scores also show higher values of body image dissatisfaction. Conclusion We provided the first evidence of validity for a figure rating scale for Brazilian adolescents.
Bishara, Saied; Kaplan, Shani
The goal of the research was to examine executive functioning and figurative language comprehension among students with learning disabilities as compared to students without learning disabilities. As part of the research, we examined 20 students with learning disabilities and 21 students with no learning disabilities, both groups of students…
Rabal, H.J.; Garavaglia, M.
Using a Fabry-Perot interferometer and a spectrograph, iluminated with white light, ondulatory spectra are obtained. The componentes are not equidistance among them and the intensity distribution obeys the Airy's law. It is been made preliminar experiments to determinate if the moire figures, generated by the ondulatory spectra interaction, allows to measure displacements, rotations, etc [es
Rabinowitz, H. S.; Barth, A.; Russell, J. B.; Frischkorn, K.; Yehudai, M.
As scientists, we spend a significant amount of time thinking about how best to express the results of our research through figures. These can range from graphs to microscope images to movies, but they all serve the purpose of communicating complicated ideas to our colleagues in the scientific community. One component of scientific data representation that is often overlooked is the aesthetic of the image. Many images produced for data communication and publication are visually engaging even to a lay audience, allowing them to serve as a point of entry to learning about scientific research for the non-specialist. To help researchers embrace this secondary goal of scientific figures, we have instituted an annual event at the Lamont-Doherty Earth Observatory of Columbia University (LDEO) called Research as Art. For this event, scientists submit figures from their work that they see as artistic. These figures are displayed in a gallery-type exhibit for the community to appreciate. This year, the exhibit included movie and sculpture categories, allowing for attendees to interact with a broader range of scientific work. Each piece is accompanied by a brief, non-technical caption. Research as Art provides a gateway for scientists from a broad range of disciplines within the Earth Sciences to learn about work that is entirely unrelated to their own. After the event, attendees commented that they had never before thought about how a non-specialist would view their figures and that they would keep this in mind when making future figures. Thus, one of the biggest benefits of exhibits such as this is to teach scientists to view our work through a non-specialist's eyes. However, future plans for Research as Art include establishing a temporary exhibit at a local bar to expand the reach to a broader segment of the Columbia University area community. Our figures are art, and when we start to treat them that way, we open a world of possibilities for teaching the public about our
Full Text Available This paper is intended to provide a critical overview of experimental and clinical research documenting problems in figurative language processing in atypical populations with a focus on the Autistic Spectrum. Research in the comprehension and processing of figurative language in autism invariably documents problems in this area. The greater paradox is that even at the higher end of the spectrum or in the cases of linguistically talented individuals with Asperger syndrome, where structural language competence is intact, problems with extended language persist. If we assume that figurative and extended uses of language essentially depend on the perception and processing of more concrete core concepts and phenomena, the commonly observed failure in atypical populations to understand figurative language remains a puzzle.Various accounts have been offered to explain this issue, ranging from linking potential failure directly to overall structural language competence (Brock et al., 2008; Norbury, 2005 to right-hemispheric involvement (Gold and Faust, 2010. We argue that the dissociation between structural language and figurative language competence in autism should be sought in more general cognitive mechanisms and traits in the autistic phenotype (e.g., in terms of weak central coherence, Vulchanova et al., 2012b, as well as failure at on-line semantic integration with increased complexity and diversity of the stimuli (Coulson and van Petten, 2002. This perspective is even more compelling in light of similar problems in a number of conditions, including both acquired (e.g., Aphasia and developmental disorders (Williams Syndrome. This dissociation argues against a simple continuity view of language interpretation.
Vulchanova, Mila; Saldaña, David; Chahboun, Sobh; Vulchanov, Valentin
This paper is intended to provide a critical overview of experimental and clinical research documenting problems in figurative language processing in atypical populations with a focus on the Autistic Spectrum. Research in the comprehension and processing of figurative language in autism invariably documents problems in this area. The greater paradox is that even at the higher end of the spectrum or in the cases of linguistically talented individuals with Asperger syndrome, where structural language competence is intact, problems with extended language persist. If we assume that figurative and extended uses of language essentially depend on the perception and processing of more concrete core concepts and phenomena, the commonly observed failure in atypical populations to understand figurative language remains a puzzle. Various accounts have been offered to explain this issue, ranging from linking potential failure directly to overall structural language competence (Norbury, 2005; Brock et al., 2008) to right-hemispheric involvement (Gold and Faust, 2010). We argue that the dissociation between structural language and figurative language competence in autism should be sought in more general cognitive mechanisms and traits in the autistic phenotype (e.g., in terms of weak central coherence, Vulchanova et al., 2012b), as well as failure at on-line semantic integration with increased complexity and diversity of the stimuli (Coulson and Van Petten, 2002). This perspective is even more compelling in light of similar problems in a number of conditions, including both acquired (e.g., Aphasia) and developmental disorders (Williams Syndrome). This dissociation argues against a simple continuity view of language interpretation.
Vulchanova, Mila; Saldaña, David; Chahboun, Sobh; Vulchanov, Valentin
This paper is intended to provide a critical overview of experimental and clinical research documenting problems in figurative language processing in atypical populations with a focus on the Autistic Spectrum. Research in the comprehension and processing of figurative language in autism invariably documents problems in this area. The greater paradox is that even at the higher end of the spectrum or in the cases of linguistically talented individuals with Asperger syndrome, where structural language competence is intact, problems with extended language persist. If we assume that figurative and extended uses of language essentially depend on the perception and processing of more concrete core concepts and phenomena, the commonly observed failure in atypical populations to understand figurative language remains a puzzle. Various accounts have been offered to explain this issue, ranging from linking potential failure directly to overall structural language competence (Norbury, 2005; Brock et al., 2008) to right-hemispheric involvement (Gold and Faust, 2010). We argue that the dissociation between structural language and figurative language competence in autism should be sought in more general cognitive mechanisms and traits in the autistic phenotype (e.g., in terms of weak central coherence, Vulchanova et al., 2012b), as well as failure at on-line semantic integration with increased complexity and diversity of the stimuli (Coulson and Van Petten, 2002). This perspective is even more compelling in light of similar problems in a number of conditions, including both acquired (e.g., Aphasia) and developmental disorders (Williams Syndrome). This dissociation argues against a simple continuity view of language interpretation. PMID:25741261
Macias B, L.R.
The preferential orientation, not alone it exists in metals, but also in minerals or in general in crystalline materials, notwithstanding in the metals it can be transformed by means of those processes of having mechanical worked such as laminate, wrapping, etc. To the preferable orientation of the crystals is also known as texture and since the properties of the crystalline materials lens depend on the orientation that present its glasses, it is important to know its texture. The difficulty for to represent and to describe the grade of preferential orientation in textured materials take to F. Weber to adapt the stereo graphic projection of a monocrystal to a poles figure. Later on, its appeared but methods to obtain the polar figure, among them, that of reflection of L. G. Schultz, but again a technique appears it specifies for its obtaining. In all the cases, the methodology is the following one: a) It is obtained by means of the diffraction process, the correspondent spectra in digitized form. b) it is applied process of having softened mathematician of the spectrum. c) there are determined the fi coordinates, beta and intensity for graph nts of the polar figure. d) Its are graph the points generated in c obtaining the polar figures. The objective of this work, is leaving of a softened spectra, to generate the coordinated fi, beta and corresponding intensity to proceed to their graph and generation of the polar figure. In this specific work, the methodology of Philips is used that consists in making a sweeping in hairspring form with the radiation to detect in these points the execution of the Bragg law. (Author)
Craker, L.E.; Starbuck, J.S.
Metabolic processes in primary leaves of bean plants (Phaseolus vulgaris) were altered by ozone stress. Decreases in levels of ribonucleic acid (RNA) and protein, and increases in ribonuclease (RNase) and free amine groups were associated with visible oxidant injury to the leaves. It appears that some air pollution injury to plants may result from changes in metabolic processes. 23 references, 5 figures, 2 tables.
Though figure-ground assignment has been shown to be probably affected by recognizability, it appears sensible that object recognition must follow at least the earlier process of figure-ground segregation. To examine whether or not rudimentary object recognition could, counterintuitively, start even before the completion of the stage of parsing in which figure-ground segregation is done, participants were asked to respond, in a go/no-go fashion, whenever any out of 16 alternative connected patterns (that constituted familiar stimuli in the upright orientation) appeared. The white figure of the to-be-attended stimulus-target or foil-could be segregated from the white ambient ground only by means of a frame surrounding it. Such a frame was absent until the onset of target display. Then, to manipulate organizational quality, the greyness of the frame was either gradually increased from zero (in Experiment 1) or changed abruptly to a stationary level whose greyness was varied between trials (in Experiments 2 and 3). Stimulus recognizability was manipulated by orientation angle. In all three experiments the effect of recognizability was found to be considerably larger when organizational quality was minimal due to an extremely faint frame. This result is argued to be incompatible with any version of a serial thesis suggesting that processing aimed at object recognition starts only with a good enough level of organizational quality. The experiments rather provide some support to the claim, termed here "early interaction hypothesis", positing interaction between early recognition processing and preassignment parsing processes.
Full Text Available During the second half of the XIXth century, Europe, the United States and Russia witnessed a blossoming interest in the use of photography in the anthropological field, its specific use was not very clear and defined yet; as a consequence, its heuristic methodologies, technical shooting modalities, stylistic elements and figurative conventions were not clear either. We range goes from anthropometric photography to an ethnographic and folkloric portrait painting signed at the same time by anthropologists and travellers, professional photographers looking for exotic subjects, amateur photographers and soldiers who encourage a figural medley characterised by scientific, commercial and artistic veins that slowly finds its definition in some of its prevailing features, in primis those of the portrait with pictorial origins, however continuously declined and reinterpreted in several ways. In this context Anthropology seeks some links with aesthetics.
Mensah, N.G.; Nkrumah-Buandoh, G.K.; Mensah, S.Y.; Allotey, F.K.A.; Twum, A.K.
We have investigated the thermoelectrical properties of chiral carbon nanotube and numerically evaluated the figure of merit. We observed that the properties are highly anisotropic and depend on the geometric chiral angle (GCA) θ h , temperature and the overlapping integrals (exchange energy) for the jumps along the tubular axis Δ z and the base helix Δ s . The thermopower α exhibited giant values with the peak occurring between 100 K and 150 K. The electron thermal conductivity showed unusually high value with the peaks shifting towards high temperature. We attribute the high peak values to electron-phonon interactions. Finally we noted that by changing the Δ s and Δ z it is possible to get a figure of merit greater than 1. (author)
Sugihara, Tadashi; Tsuji, Yoshihisa; Sakai, Ko
A recent physiological finding of neural coding for border ownership (BO) that defines the direction of a figure with respect to the border has provided a possible basis for figure-ground segregation. To explore the underlying neural mechanisms of BO, we investigated stimulus configurations that activate BO circuitry through psychophysical investigation of the BO-dependent tilt aftereffect (BO-TAE). Specifically, we examined robustness of the border ownership signal by determining whether the BO-TAE is observed when gestalt factors are broken. The results showed significant BO-TAEs even when a global shape was not explicitly given due to the ambiguity of the contour, suggesting a contour-independent mechanism for BO coding.
Kandil, Farid I; Fahle, Manfred
Inhomogenous displays, in contrast to homogenous ones, evoke a specific potential in the VEP (tsVEP) which appears across different classical visual stimulus dimensions defining figure-ground segregation, such as luminance, orientation, (first-order) motion, and stereoscopic depth. This negative potential has a peak latency of about 200-300 ms and a peak amplitude of about -3 to -10 microV [Doc Ophthalmol. 95 (1998) 335]. Previously, we demonstrated that human subjects reliably segregate figure from ground, even in the absence of the classical cues, leaving time of change as the only cue for segregation. The results of the present study demonstrate that also purely temporally defined checkerboards evoke a tsVEP resembling the motion-defined tsVEP regarding polarity (negative), latency (two peaks at 180 and 270 ms, respectively), amplitude of the first negativity (-5.6 microV), and overall form of its components.
Derbenev, Yaroslav S. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Morozov, Vasiliy [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Lin, Fanglei [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Zhang, Yuhong [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Kondratenko, A. M. [GOO Zaryad, Russkaya st., 41, Novosibirsk, 630058; Kondratenko, M. A. [GOO Zaryad, Russkaya st., 41, Novosibirsk, 630058; Filatov, Yuri [Joint Inst. for Nuclear Research (JINR), Dubna (Russian Federation); GOO Zaryad, Russkaya st., 41, Novosibirsk, 630058
We present a complete scheme for managing the polarization of ion beams in Jefferson Lab's proposed Medium-energy Electron-Ion Collider (MEIC). It provides preservation of the ion polarization during all stages of beam acceleration and polarization control in the collider's experimental straights. We discuss characteristic features of the spin motion in accelerators with Siberian snakes and in accelerators of figure-8 shape. We propose 3D spin rotators for polarization control in the MEIC ion collider ring. We provide polarization calculations in the collider with the 3D rotator for deuteron and proton beams. The main polarization control features of the figure-8 design are summarized.
Wang, David H; Kostyun, Regina O; Solomito, Matthew J
Several facets of figure skating, such as the forces associated with jumping and landing, have been evaluated, but a comprehensive biomechanical understanding of the cranial forces associated with spinning has yet to be explored. The purpose of this case study was to quantify the cranial rotational acceleration forces generated during spinning elements. This case report was an observational, biomechanical analysis of a healthy, senior-level, female figure skating athlete who is part of an on-going study. A triaxial accelerometer recorded the gravitational forces (G) during seven different spinning elements. Our results found that the layback spin generated significant cranial force and these forces were greater than any of the other spin elements recorded. These forces led to physical findings of ruptured capillaries, dizziness, and headaches in our participant.
Mc Leod, David Matthew; Mc Leod, Roger David
12/21/98, at America's Stonehenge, DMM detected, and drew, the full stick-figure equivalent of Canis Major, CM, as depicted by our Wolf Clan leaders, and many others. Profound, foundational physics is implied, since this occurred in the Watch House there, hours before the ``model rose.'' Similar configurations like Orion, Osiris of ancient Egypt, show that such figures are projected through solid parts of the Earth, as two-dimensional equivalents of the three-dimensional star constellations. Such ``sticks'' indicate that ``line equivalents'' connect the stars, and the physical mechanism projects outlines detectable by traditional cultures. We had discussed this ``flashlight'' effect, and recognized some of its implications. RDM states that the flashlight is a strong, distant neutrino source; the lines represent neutrinos longitudinally aligned in gravitational excitation, opaque, to earthbound, transient, transversely excited neutrinos. ``Sticks'' represent ``graviton'' detection. Neutrinos' longitudinal alignment accounts for the weakness of gravitational force.
Figure summarizes uncertainty (error) in hourly gradient flux measurements by individual analyte. Flux uncertainty is derived from estimates of uncertainty in chemical gradients and turbulent transfer velocity.This dataset is associated with the following publication:Rumsey, I. Application of an online ion chromatography-based instrument for gradient flux measurements of speciated nitrogen and sulfur. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 9(6): 2581-2592, (2016).
This article provides a critique of governmentally inspired accounts of urban regeneration and partnership working. Drawing on the work of Norbert Elias and prominent figurational sociologists, it discusses the changes taking place within and through the many partnerships set up by New Labour around the notion of ‘community safety’. Although recognizing the important insights provided by accounts of urban regeneration emerging through studies of governmentality, the article argues that such a...
space reach and vision analyses, while others are used to examine biomechanics or strength issues, for example. Still other human figure modeling...identified that the crewstation design did not allow small pilots to reach the pedals and instrument panels. Small females were unable to view the...the ECLs; improved seat adjustment to allow access to the pedals and front instrument panels for small female aviators; and increased volume of space
Im Zentrum des Aufsatzes steht die systematische Funktion des ‚Wetteifers‛ in der praktischen Philosophie Kants. Zwar taucht der ‚Wetteifer‛ in vielfältigem Zusammenhang in Kants Anthropologischen Schriften auf, dennoch wird er in Bezug auf ethische Fragen selten in Betracht gezogen. Auch wenn es richtig ist, dass ‚Wetteifer‛ dort nicht im Sinne des marktwirtschaftlichen Wettbewerbs verwendet wird, handelt es sich doch strukturell um die gleiche interaktionsbasierte Figur – wie wir sie auch i...
Poulsen, Melissa Eriko
This dissertation examines figurations of Asian mixed race during the long period of Asian exclusion and enforced anti-miscegenation in the United States, when racial mixing was legally proscribed. During this time of U.S. expansion into Asia, and of unprecedented Asian immigration into the United States, such proscription helped maintain normative white identity while rendering the Asian American mixed-race body illegible, making cultural production one of the few sites where Asian American ...
Kienker, P K; Sejnowski, T J; Hinton, G E; Schumacher, L E
The differentiation of figure from ground plays an important role in the perceptual organization of visual stimuli. The rapidity with which we can discriminate the inside from the outside of a figure suggests that at least this step in the process may be performed in visual cortex by a large number of neurons in several different areas working together in parallel. We have attempted to simulate this collective computation by designing a network of simple processing units that receives two types of information: bottom-up input from the image containing the outlines of a figure, which may be incomplete, and a top-down attentional input that biases one part of the image to be the inside of the figure. No presegmentation of the image was assumed. Two methods for performing the computation were explored: gradient descent, which seeks locally optimal states, and simulated annealing, which attempts to find globally optimal states by introducing noise into the computation. For complete outlines, gradient descent was faster, but the range of input parameters leading to successful performance was very narrow. In contrast, simulated annealing was more robust: it worked over a wider range of attention parameters and a wider range of outlines, including incomplete ones. Our network model is too simplified to serve as a model of human performance, but it does demonstrate that one global property of outlines can be computed through local interactions in a parallel network. Some features of the model, such as the role of noise in escaping from nonglobal optima, may generalize to more realistic models.
Full Text Available Getting in front of painting by Francis Bacon touches you deeply. I’m talking about aesthetics, sensations: resounding flow that strikes abruptly, making futile any search for meaning. Francis Bacon circumvents the figurative, the meaning, he aims to the figural: to feelings, not words. Beauty, in his paintings, shows itself in the peaceful union of the positive and of its contrary; if the negative wasn’t there, though, his paintings wouldn’t exude such a brutal sense of reality. This essay investigates the figure of Francis Bacon and the spectator – the Other – as he tries to confront the painting. Bacon will be analysed using a purely phenomenological approach, with references that range from Merleau-Ponty to Martin Heidegger; the meeting-collision between the spectator and the painting, instead, will be examined taking inspiration from the Winnicott’s thesis on the relationship between Bacon and mirrors in the painter’s childhood. In order to take distance from Winnicott’s psychoanalytical approach, this essay will focus on the relationship between spectator and painting from a more anthropological point of view.
Full Text Available The purpose of this article is to enquire into the notion of change in figures of speech, concepts, topics, and technical instruments-models when they are “travelling” through different milieus, contexts, systems or disciplines. I conceive of this travelling as a basic exchange of energy/information, amounting to an event which can reshape a given field of experience. My argument is based on the premise that our experience happens at multiple levels and areas, and develops along different phases, which imperceptibly flow into each other and bear at times barely decipherable traces of the events that have constituted them. The processes happening at a different level from that of present perception can only be conceived of as infractions of the world tissue and of the related universe of discourse. Therefore in any field of enquiry the process of discovery can develop only through figures of discourse. My thesis is that, at the present stage of techno-science, Scriptural Figurality, which constitutes the basis of both Western epistemology and hermeneutics, is superseded and has to be replaced by a new hypermedial rhetoric, capable to cope with complexity, infraction and emergence, both in science and the humanities.
Roelfsema, Pieter R; Lamme, Victor A F; Spekreijse, Henk; Bosch, Holger
Here we propose a model of how the visual brain segregates textured scenes into figures and background. During texture segregation, locations where the properties of texture elements change abruptly are assigned to boundaries, whereas image regions that are relatively homogeneous are grouped together. Boundary detection and grouping of image regions require different connection schemes, which are accommodated in a single network architecture by implementing them in different layers. As a result, all units carry signals related to boundary detection as well as grouping of image regions, in accordance with cortical physiology. Boundaries yield an early enhancement of network responses, but at a later point, an entire figural region is grouped together, because units that respond to it are labeled with enhanced activity. The model predicts which image regions are preferentially perceived as figure or as background and reproduces the spatio-temporal profile of neuronal activity in the visual cortex during texture segregation in intact animals, as well as in animals with cortical lesions.
William A. Sands
Full Text Available Trends in pairs figure skating have shown that increasingly difficult jumps have become an essential aspect of high-level performance, especially in the latter part of a competitive program. We compared a repeated jump power index in a 60 s repeated jump test to determine the relationship of repeated jump test to competitive rank and to measure 2D hip, knee, and ankle angles and angular velocities at 0, 20, 40, and 60 s. Eighteen National Team Pairs Figure Skaters performed a 60 s repeated jump test on a large switch-mat with timing of flight and ground durations and digital video recording. Each 60-s period was divided into 6, 10-s intervals, with power indexes (W/kg calculated for each 10-s interval. Power index by 10-s interval repeated measures ANOVAs (RMANOVA showed that males exceeded females at all intervals, and the highest power index interval was during 10 to 20 s for both sexes. RMANOVAs of angles and angular velocities showed main effects for time only. Power index and jumping techniques among figure skaters showed rapid and steady declines over the test duration. Power index can predict approximately 50% of competitive rank variance, and sex differences in jumping technique were rare
Full Text Available Despite the prognostic importance of mitotic count as one of the components of the Bloom – Richardson grade , several studies ([2, 9, 10] have found that pathologists’ agreement on the mitotic grade is fairly modest. Collecting a set of more than 4,200 candidate mitotic figures, we evaluate pathologists' agreement on individual figures, and train a computerized system for mitosis detection, comparing its performance to the classifications of three pathologists. The system’s and the pathologists’ classifications are based on evaluation of digital micrographs of hematoxylin and eosin stained breast tissue. On figures where the majority of pathologists agree on a classification, we compare the performance of the trained system to that of the individual pathologists. We find that the level of agreement of the pathologists ranges from slight to moderate, with strong biases, and that the system performs competitively in rating the ground truth set. This study is a step towards automatic mitosis count to accelerate a pathologist's work and improve reproducibility.
添田, 佳伸; 藤井, 良宜
In learning geometry we often use iconic figures to give children conditions and questions in word problems. But the figure becomes an object of thinking after finishing plaing the role of giving some information. Children think the problem by using the given figure. If figures influence chidren's thinking, a rate of correct answer of each problem must be different according to being presented each figure. ### Thus we investigated the differences of rates of correct answer by using three type...
Strother, Lars; Lavell, Cheryl; Vilis, Tutis
We used fMRI to study figure-ground representation and its decay in primary visual cortex (V1). Human observers viewed a motion-defined figure that gradually became camouflaged by a cluttered background after it stopped moving. V1 showed positive fMRI responses corresponding to the moving figure and negative fMRI responses corresponding to the static background. This positive-negative delineation of V1 "figure" and "background" fMRI responses defined a retinotopically organized figure-ground representation that persisted after the figure stopped moving but eventually decayed. The temporal dynamics of V1 "figure" and "background" fMRI responses differed substantially. Positive "figure" responses continued to increase for several seconds after the figure stopped moving and remained elevated after the figure had disappeared. We propose that the sustained positive V1 "figure" fMRI responses reflected both persistent figure-ground representation and sustained attention to the location of the figure after its disappearance, as did subjects' reports of persistence. The decreasing "background" fMRI responses were relatively shorter-lived and less biased by spatial attention. Our results show that the transition from a vivid figure-ground percept to its disappearance corresponds to the concurrent decay of figure enhancement and background suppression in V1, both of which play a role in form-based perceptual memory.
Albin, E. F. M.
In the current investigation, details on the construction and performance of a vacuum-flexed (i.e., figured) 51 cm (20-inch) mirror, with a fast f/4 focal ratio, are presented. A vacuum has the chief advantage of being able to pull with a uniform or isotropic stress across a large surface area, which will naturally form a parabolic surface. The essence of the idea is to grind and polish a spherical mirror and then warp or flex it into a near perfect paraboloid, thus avoiding tedious figuring altogether. To date, telescope makers around the globe have experimented with small flexed mirrors with considerable success. In these instances, mirrors have been flexed by exerting tension on a bolt or sponge-pad adhered to the back of the mirror. The prototype mirror consists of two 51 cm disks of plate glass -- each slumped to an f/4 focal ratio. The front-plate (19 mm in thickness) is separated from the back-plate (13 mm in thickness) back a flexible 9.5 mm air filled gasket. Although the rubber gasket makes a fairly good vacuum seal, silicon cement was placed about the outer edge in order to produce a perfectly tight seal. A vacuum of 8 kPa on the back of the mirror resulted in approximately 164 kilograms of negative pressure, which is required to flex the mirror into the required paraboloid. Ronchi test show a nice smooth paraboloid free from astigmatism while foucault zonal measurements display a figure better than 1/20 wave. Preliminary star testing show promising results as well. Vacuum-flexed mirrors may have benefits for both amateur and professional telescope makers alike. A US patent is pending on the aforementioned design.
Kandil, Farid I; Fahle, Manfred
Figure-ground segregation can rely on purely temporal information, that is, on short temporal delays between positional changes of elements in figure and ground (Kandil, F.I. & Fahle, M. (2001) Eur. J. Neurosci., 13, 2004-2008). Here, we investigate the underlying mechanisms by measuring temporal segregation thresholds for various kinds of motion cues. Segregation can rely on monocular first-order motion (based on luminance modulation) and second-order motion cues (contrast modulation) with a high temporal resolution of approximately 20 ms. The mechanism can also use isoluminant motion with a reduced temporal resolution of 60 ms. Figure-ground segregation can be achieved even at presentation frequencies too high for human subjects to inspect successive frames individually. In contrast, when stimuli are presented dichoptically, i.e. separately to both eyes, subjects are unable to perceive any segregation, irrespective of temporal frequency. We propose that segregation in these displays is detected by a mechanism consisting of at least two stages. On the first level, standard motion or flicker detectors signal local positional changes (flips). On the second level, a segregation mechanism combines the local activities of the low-level detectors with high temporal precision. Our findings suggest that the segregation mechanism can rely on monocular detectors but not on binocular mechanisms. Moreover, the results oppose the idea that segregation in these displays is achieved by motion detectors of a higher order (motion-from-motion), but favour mechanisms sensitive to short temporal delays even without activation of higher-order motion detectors.
Hu, X. K., E-mail: email@example.com; Krzysteczko, P.; Liebing, N.; Schumacher, H. W. [Physikalisch-Technische Bundesanstalt, Bundesallee 100, D-38116 Braunschweig (Germany); Serrano-Guisan, S. [International Iberian Nanotechnology Laboratory, Av. Mestre José Veiga, 4715-330 Braga (Portugal); Rott, K.; Reiss, G. [Fakultät für Physik, Universität Bielefeld, Postfach 100131, D-33501 Bielefeld (Germany); Kimling, J.; Böhnert, T.; Nielsch, K. [Institut für Angewandte Physik, Universität Hamburg, Jungiusstraße 11, D-20355 Hamburg (Germany)
The switching of the magnetic configuration of giant magnetoresistance multilayers not only changes the electrical and thermal conductivities but also the thermopower. We study the magnetotransport and the magnetothermoelectric properties of Co/Cu multilayer devices in a lateral thermal gradient. The Seebeck coefficient reaches values up to −18 μV/K at room temperature and shows a magnetic field dependence up to 28.6% upon spin reversal. In combination with thermal conductivity data of the same Co/Cu stack, we find a magnetothermoelectric figure of merit of up to 65%. Furthermore, a magneto-power factor of up to 110% is derived.
ACKNOWLEDGMENTS, i -- SUMMARY, ii -- CONTENTS, vi -- LIST OF FIGURES, ix -- LIST OF T ABLES, x -- 1. INTRODUCTION, 1 -- 1.0. Overview, 1 -- 1.1. The Title of the Study, 1 -- 1.2. The Scope of the Study, 1 -- 1.3. The Purpose and Research Rationale, 1 -- 1.4. The Research Methodology, 2 -- 1.5. Sources of Data, 2 -- 1.6. Benefits Expected from the Thesis, 2 -- 1.7. Limits of the Thesis, 3 -- 1.8. Structure of the Thesis, 3 -- 2. POLITICAL MARKETING, 5 -- 2.0. Overview, 5 -- 2.1. Theoretical Ba...
Huang, Liqiang; Pashler, Harold
Human visual perception is sometimes ambiguous, switching between different perceptual structures, and shifts of attention sometimes favor one perceptual structure over another. It has been proposed that, in figure-ground segmentation, attention to certain regions tends to cause those regions to be perceived as closer to the observer. Here, we show that this attention effect can be reversed under certain conditions. To account for these phenomena, we propose an alternative principle: The visual system chooses the interpretation that maximizes simplicity of the attended regions.
Full Text Available This paper describes the steps taken to eliminate two of the items in a Test of Figural Analogies (TFA. The main guidelines of psychometric analysis concerning Classical Test Theory (CTT and Item Response Theory (IRT are explained. The item elimination process was based on both the study of the CTT difficulty and discrimination index, and the unidimensionality analysis. The a, b, and c parameters of the Three Parameter Logistic Model of IRT were also considered for this purpose, as well as the assessment of each item fitting this model. The unfavourable characteristics of a group of TFA items are detailed, and decisions leading to their possible elimination are discussed.
Full Text Available Attraverso due racconti di Cortázar, l'analisi di due figure del desiderio ci permette esplorare due estremi seguendo una verticalità. La distruzione, doppio tenebroso della nostra anima, ci rivela un erotismo legato alla morte e al desiderio morboso di possedere l'Altro; il suo contraltare è un'ascesa vertiginosa accompagnata da un godimento estetico, dall'amore sublime prossimo all'esperienza mistica che si concluderà con una discesa progressiva e nel rispetto di questo Altro. La creazione letteraria si presenta come uno sfogo alle nostre angosce, che sono anche una sorta d'espressione dell'erotismo.
Knudson, R.; Sciacca, F.; Walsh, R.; Zigler, G.
One of the requirements for nuclear plant license renewal may be the establishment and demonstration of an effective aging management program. An analysis of both qualitative and quantitative information will be required to define the contents of this aging management program. The authors propose two quantitative figures of merit, Mean Event Detection Frequency and Mean Renewal Rate, that can be used to compare the effectiveness of various inspection, surveillance, test, and monitoring (ISTM) activities for aging mitigation. An example showing the relative effectiveness of an enhanced Loose Parts Monitoring System with current ISTM activities for steam generators and reactor internals is provided. (author)
‘Figure-ground’ is about the production of meaning based on the perception of contrasts or binary oppositions and segregations. Viewers of my paintings, and of the kind of paintings that interest me, have the impression that the ‘figure’ subsides or slips or fades into ‘ground’, or that the ‘ground’ is more powerful or dominant than the‘figure’, or that the ‘figure’ is insecurely attached, suggesting it is incapable, unwilling, too acquiescent or complicit to fully differentiate itself from t...
Jabbari, Hosna; Aminpour, Maral; Montemagno, Carlo
Recent advances in experimental DNA origami have dramatically expanded the horizon of DNA nanotechnology. Complex 3D suprastructures have been designed and developed using DNA origami with applications in biomaterial science, nanomedicine, nanorobotics, and molecular computation. Ribonucleic acid (RNA) origami has recently been realized as a new approach. Similar to DNA, RNA molecules can be designed to form complex 3D structures through complementary base pairings. RNA origami structures are, however, more compact and more thermodynamically stable due to RNA's non-canonical base pairing and tertiary interactions. With all these advantages, the development of RNA origami lags behind DNA origami by a large gap. Furthermore, although computational methods have proven to be effective in designing DNA and RNA origami structures and in their evaluation, advances in computational nucleic acid origami is even more limited. In this paper, we review major milestones in experimental and computational DNA and RNA origami and present current challenges in these fields. We believe collaboration between experimental nanotechnologists and computer scientists are critical for advancing these new research paradigms.
Grossberg, S; Pessoa, L
A widespread view is that most texture segregation can be accounted for by differences in the spatial frequency content of texture regions. Evidence from both psychophysical and physiological studies indicate, however, that beyond these early filtering stages, there are stages of 3-D boundary segmentation and surface representation that are used to segregate textures. Chromatic segregation of element-arrangement patterns--as studied by Beck and colleagues--cannot be completely explained by the filtering mechanisms previously employed to account for achromatic segregation. An element arrangement pattern is composed of two types of elements that are arranged differently in different image regions (e.g. vertically on top and diagonally on the bottom). FACADE theory mechanisms that have previously been used to explain data about 3-D vision and figure-ground separation are here used to simulate chromatic texture segregation data, including data with equiluminant elements on dark or light homogeneous backgrounds, or backgrounds composed of vertical and horizontal dark or light stripes, or horizontal notched stripes. These data include the fact that segregation of patterns composed of red and blue squares decreases with increasing luminance of the interspaces. Asymmetric segregation properties under 3-D viewing conditions with the equiluminant elements close or far are also simulated. Two key model properties are a spatial impenetrability property that inhibits boundary grouping across regions with non-collinear texture elements and a boundary-surface consistency property that uses feedback between boundary and surface representations to eliminate spurious boundary groupings and separate figures from their backgrounds.
Pors, Anja Svejgaard
The purpose of this paper is to examine how strategic, patient-centred communication plays a part in the discursive management of expectations posed to patients and healthcare organizations. The paper provides an analysis of four documents collected as part of an ethnographic case study regarding "The Perspective of the Patient" - a Danish Hospital's patient-centred communication programme. Mapping methods inspired by Grounded Theory are used to qualify the analysis. The paper shows that strategic patient-centred communication addresses both a care-oriented approach to the patient and deploys market perceptions of patients. Market and care is seen as co-existing organizing modes that entail expectations to the patient. In the communication programme the patient is constructed in six information-seeking patient figures: affective patient; target group patient; citizen with rights; patient as a competent resource; user as active partner; and consumer. As a result, the patient-centred communication programme renders the patient as a flexible figure able to fit organizational demands of both care orientation and market concerns. This study contributes to qualitative research in organizational health communication by combining two subfields - patient-centredness and health communication - in an empirical study of how market and care are intertwined in a patient-centred communication programme. The argument goes beyond the prevalent prescriptive approaches to patient-centredness and healthcare communication, instead providing a critical analytical perspective on strategic communication and patient-centredness and showing how expectations are posed to both patient and organization.
Pinna, Baingio; Reeves, Adam; Koenderink, Jan; van Doorn, Andrea; Deiana, Katia
The problem of perceptual organization was studied by Gestalt psychologists in terms of figure-ground segregation. In this paper we explore a new principle of figure-ground segregation: accentuation. We demonstrate the effectiveness of accentuation relative to other Gestalt principles, and also consider it autonomous as it can agree with or oppose them. We consider three dynamic aspects of the principle, namely: attraction, accentuation and assignment. Each creature needs to attract, fascinate, seduce, draw attention (e.g., a mate or a prey animal) or distract, refuse, dissuade, discourage, repulse (e.g., a predator). Similarly, each organism needs to accentuate, highlight, stress, underline, emphasize or distract from another. Thus, accentuation assigns meaning to a visual pattern such as a coat, a plumage or a flower. False eyes (ocelli) and dots (diematic patterns) demonstrate "deceiving camouflage by accentuation" that confuses predators/preys and hides or highlights vital body parts (butterflies/flowers). They also display the deceiving appearance and exhibition of biological fitness. The same accents may serve different or even opposite goals. We conclude that accentuation improves the adaptive fitness of organisms in multifarious ways. Copyright © 2017 Elsevier Ltd. All rights reserved.
Full Text Available In her 1975 essay, Le Rire de la méduse , Hélène Cixous enthusiastically announced that it was high time for women to enter into discourse. A full half-century earlier, Claude Cahun (1894-1954, a powerful writer and a haunting photographer and artist, was already inscribing herself, Woman, and a woman's voice in visual and verbal self-portraits, photomontages, prose texts, poetry, and aesthetic and political treatises. Cahun's uncanny interventions in both verbal and visual discourse cannily interrogate conventions of literary and pictorial representation and the constructions of self, gender and culture that they exhibit. Insistently asking readers and spectators, "What's wrong with this picture?," her carnivalesque play with the doxa and the politics of identity, destabilizes not only gender and genre norms, but the boundaries and distinctions between visual and verbal representation. Surreal and Canny Selves explores the aesthetic frameworks of writer/artist Claude Cahun. Elucidating how Cahun's questioning of her self and Surrealist representations of woman were part of a much more expansive adventure that questioned more than femininity—the manuscript moves on to trace how and what Cahun's foregrounding of figuration and, more specifically, photographic figuration, might signify for the uncanny aesthetic practices deployed in the hybrid text Aveux non avenus .
Pantelidou, Maria; Demetriades, Andreas K
In spite of his contribution to psychiatry in 19th century Britain, Henry Maudsley remains a mysterious figure, a man mostly known for his donation to the London County Council for the building of the Maudsley Hospital and for The Maudsley Annual Lecture created in honour of his benevolence. Besides Sir Aubrey Lewis' article in 1951 and Michael Collie's attempt in 1988 to construct a biographical study on Maudsley, there does not seem to be any current endeavour to tell the story of his life, whereas Trevor Turner's contribution to the 2004 Oxford Dictionary of National Biography gives a somewhat scathing but unattributed account of Maudsley's personality. This essay attempts to explore his contributions to the Medico-Psychological Association (MPA), the current Royal College of Psychiatrists, his editorship of the Journal of Mental Health (currently named the British Journal of Psychiatry), his literary contributions and his vision for a psychiatric hospital. This essay is an attempt to demystify his figure and to explore some of the rumours and criticisms surrounding his name and the reasons why so little has been written about him. It is also a venture to unravel his complex personality and his intricate philosophy. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.
After an indication of some remarkable key figures (general data, data about office building, housing, industries, renewable energies, wastes, transports, agriculture and forests, and households, indication of some French and European objectives for 2020 and 2030), and a table containing indications of some international official texts (Kyoto protocol and its amendment, European directives) and of their content and scope (bio-fuels in transports, energy efficiency, buildings, labelling and eco-design, transports, renewable energies, energy and climate, greenhouse gas emissions and adaptation, air quality, wastes), and national texts (laws, plans) regarding the same issues, this publication presents figures and data under the form of graphs and tables to illustrate their evolution. They are general data on energy consumptions and intensities (data per sector and per country in Europe), markets and jobs related to renewable energies, certificates of energy saving, greenhouse gas emissions and climate change, regional data for France. The other chapters present large sets of graphs and tables of relevant data concerning housing buildings, office buildings, transports, industries, agriculture and forests, renewable energies and heat networks, wastes, and households. Generally, these data are presented in terms of evolution since the 1970's or the 1990's. They propose a detailed analytical point of view of the various energy and energy-related issues in these different sectors and fields
Pinna, Baingio; Penna, Maria Pietronilla
The watercolor illusion is characterized by a large-scale assimilative color spreading (coloration effect) emanating from thin colored edges. The watercolor illusion enhances the figural properties of the colored areas and imparts to the surrounding area the perceptual status of background. This work explores interactions between cortical boundary and surface processes by presenting displays and psychophysical experiments that exhibit new properties of the watercolor illusion. The watercolor illusion is investigated as supporting a new principle of figure-ground organization when pitted against principles of surroundedness, relative orientation, and Prägnanz. The work demonstrated that the watercolor illusion probes a unique combination of visual processes that set it apart from earlier Gestalt principles, and can compete successfully against them. This illusion exemplifies how long-range perceptual effects may be triggered by spatially sparse information. All the main effects are explained by the FACADE model of biological vision, which clarifies how local properties control depthful filling-in of surface lightness and color.
Configuration for Collecting Influence Function Data ..................11 3. 4D Interferometer...24 3. Influence Function Using Interferometer ........................................25 4. Determining the Influence Matrix...10 Figure 12. Influence function configuration with flip mirror (from ). ..........................11 Figure 13. Interferometer
Kallendorf, Craig; Kallendorf, Carol
Demonstrates that business writers rely far more heavily than expected on classical figures of speech. Uses Aristotle's "Rhetoric" to show that figures of speech offer a powerful tool for the persuasive function of modern business communication. (PD)
Peterson, Mary A; Enns, James T
Viewing a stepped edge is likely to prompt the perceptual assignment of one side of the edge as figure. This study demonstrates that even a single brief glance at a novel edge gives rise to an implicit memory regarding which side was seen as figure; this edge complex enters into the figure assignment process the next time the edge is encountered, both speeding same-different judgments when the figural side is repeated and slowing these judgments when the new figural side is identical to the former ground side (Experiments 1A and 1B). These results were obtained even when the facing direction of the repeated edge was mirror reversed (Experiment 2). This study shows that implicit measures can reveal the effects of past experience on figure assignment, following a single prior exposure to a novel shape, and supports a competitive model of figure assignment in which past experience serves as one of many figural cues.
Barbeyron, R.; Vasseur, J.-J.; Smietana, M.
Abstract: The development of synthetic systems displaying dynamic and adaptive characteristics is a formidable challenge with wide applications from biotechnology to therapeutics. Recently, we described a dynamic and programmable nucleic acid-based system relying on the formation of reversible bo....... Evidence suggests that geometric and steric factors are key features for controlling the equilibria. Graphical Abstract: [Figure not available: see fulltext.]...
Two experiments investigated the role of spatial frequency in performance of a figure/ground segregation task based on temporal cues. Figure orientation was much easier to judge when figure and ground portions of the target were defined exclusively by random texture composed entirely of high spatial frequencies. When target components were defined by low spatial frequencies only, the task was nearly impossible except with long temporal delay between figure and ground. These results are incons...
Voltaire Q. Oyzon
Full Text Available Waray children are â€œunconsciously shifting from their mother language to English and/or Tagalog in their vocabulary useâ€. English vocabularies are more familiar to Waray educands of today than are the indigenous Waray terms, for instance, for geometrical figures, colors, numbers, etc. Still, â€œit is an ongoing debate of what type of language should be used in the implementation of MTBMLE.â€ Should educators use a Waray that borrows heavily from English and other languages or a Waray that uses exclusively its own indigenous terms and concepts? The researchers formulate a single lesson plan using an inductive method incorporating the Montessori Approach. We have two types of pupils at LNU-ILS: Waray pupils whose language at home is Waray, and Waray pupils who are exposed to English at home.
Peng, Jun; Kang, Stephen Dongmin; Snyder, G Jeffrey
Energy harvesting with triboelectric nanogenerators is a burgeoning field, with a growing portfolio of creative application schemes attracting much interest. Although power generation capabilities and its optimization are one of the most important subjects, a satisfactory elemental model that illustrates the basic principles and sets the optimization guideline remains elusive. We use a simple model to clarify how the energy generation mechanism is electrostatic induction but with a time-varying character that makes the optimal matching for power generation more restrictive. By combining multiple parameters into dimensionless variables, we pinpoint the optimum condition with only two independent parameters, leading to predictions of the maximum limit of power density, which allows us to derive the triboelectric material and device figure of merit. We reveal the importance of optimizing device capacitance, not only load resistance, and minimizing the impact of parasitic capacitance. Optimized capacitances can lead to an overall increase in power density of more than 10 times.
Post, Jerrold M
Questions concerning such matters as the effects of health and alcoholism on Boris Yeltsin's decision making; the mind of the Unabomber; the psychology and decision making of Saddam Hussein of Iraq, who was initially characterized by the US Government as "the madman of the Middle East"; the psychology of David Koresh and the Branch Davidians, who were involved in an extended siege with the Bureau of Alcohol, Tobacco, and Firearms and the Federal Bureau of Investigation that ended tragically on April 19, 1993; and, most recently, the psychology of the nineteen al-Qaeda terrorists responsible for the tragic events of September 11, 2001 in which they claimed thousands of lives while giving their own, "killing in the name of God," and of their charismatic leader Osama bin Laden have led journalists to turn to social scientists, including psychiatrists, to offer commentary on public figures.
Full Text Available In his pioneering History of Portraiture in Wax, Julius von Schlosser traced back the age-old history of a material which at that time seemed to be already antiquated, if not obsolete. Wax sculptures were rejected and ousted from art history because of their excessive similarity and adherence to models. One hundred years later, however, hyperrealism got its revenge with Maurizio Cattelan’s celebrated hanging children. Moving from that controversial artwork and focusing on the heated polemics over it, my paper will address the question of the well-known Unheimlichkeit of wax figures, investigated by Ernst Jentsch and Sigmund Freud in the early Twentieth Century and nowadays becoming increasingly topical thanks to the recent debate about the existence and nature of the so called Uncanny Valley.
Recent years have seen developments in cyborgian movements in which people play and experiment with the boundaries of human flesh and aesthetic realities. Some individuals develop novel intimate relationships with devices that, each in their own way, interfere with human subjectivity. Public dissemination of these movements often proposes notions of transcendence, therapy, post-humanism and trans-humanism, but often fails to outline the lived-experience of those who explore cyborgian identity as an alternative mode of being in the world. This paper briefly follows self-described cyborgs who delimit the body through sensory 'enhancement' in an effort to disrupt common relationships between the human figure and the urban ground. Borrowing from Lewis Mumford's concepts of biotechnics, I propose cyborgian engagement as a type of psychodynamic living. Rather than focus on post-human discourses, these cyborgs turn to the natural world for inspiration in shaping the terms of engagement between their bodies and the city.
Briefs describe 33 charts, graphs, and schematics offering some recent history and perspectives on the world and U.S. energy situation and the problems for survival facing the world. Of interest is Figure 28, showing the Club of Rome's model of the earth in terms of resource consumption, food, money, people, pollution, etc. A computer was asked to extend recent history into the future and results indicate a collapse of the industrialized system towards an agrarian culture around the year 2025. It is noted that the model did not consider technological initiative or man's willingness to change lifestyles. The final (33) schematic is a guesstimate of noticeable impact timescales, indicating when research projects on transition or ultimate energy sources at LASL might be expected to yield impact. (MCW)
Sullivan, Regina M
Altricial infants (i.e., requiring parental care for survival), such as humans and rats, form an attachment to their caregiver and receive the nurturing and protections needed for survival. Learning has a strong role in attachment, as is illustrated by strong attachment formed to non-biological caregivers of either sex. Here we summarize and integrate results from animal and human infant attachment research that highlights the important role of social buffering (social presence) of the stress response by the attachment figure and its effect on infant processing of threat and fear through modulation of the amygdala. Indeed, this work suggests the caregiver switches off amygdala function in rodents, although recent human research suggests a similar process in humans and nonhuman primates. This cross-species analysis helps provide insight and unique understanding of attachment and its role in the neurobiology of infant behavior within attachment.
Nielsen, Stine Maria Louring; Mullins, Michael Finbarr
from two experimental case studies on 98 patients’ well-being in relation to their experience and use of visual art during hospitalization. The case studies employed a mixed-method approach, including interviews and observations informed by thermal video recording, surveys and psychophysiological......Within the evidence-based design discourse, and deriving particularly from the theory of emotional congruence, abstract art has been indicated as unsuitable for hospitals. As patients may often experience unfamiliarity, vulnerability, stress, unpredictability and uneasiness in hospitals......, these negative factors in terms of patients’ well-being are predicted to be detrimentally reinforced by abstract art, but alleviated by particular forms of figurative art. The present paper focuses particularly on this question of the suitability of abstract art in Danish hospital settings and presents findings...
This publication provides information for the fields electricity / heat / fuels in detail on the expansion of renewable energies and illustrates this with tables and graphs. Basis of the data are the results of the Working Group on Renewable Energy Sources Statistics (AGEE-Stat), on behalf of the BMWi working out the balance of renewable energy in Germany. In addition you will also find information about Renewable Energy Law and to promote renewable Energy for heating purposes as well as for research and Development. In addition to the figures for Germany are also developments in the use of renewable energy in the European Union documented which also has set ambitious targets. Data for global Development are also included. [de
The public is unreasonably concerned and anxious about ionizing radiation. This undefined, irrational, but still real fear of something you know is there even if you cannot perceive it with your five senses is one of the greatest problems the nuclear industry has to attack today. The major problem in this case may be the technical language used by experts. The man in the street has no idea of the technical terms experts use. However, it is possible to make our message clear without the use of any units or figures. A lot can be done for the understanding and confidence by making comparisons to familiar concepts and situations, by taking off our doctors' coats and stepping down to the grass-root level to talk with people in their own everyday language. (author)
Foxe, Michael P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Miller, Brian W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Suarez, Rey [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hayes, James C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
In order to decrease the minimum detectable activities (MDAs) of beta-gamma radioxenon detectors, it is important to increase the ability to resolve the individual isotopes. One proposed method for doing this is to increase the energy resolution of the beta cell through the use of silicon detectors. While silicon detectors can improve the energy resolution, it is accompanied with a decrease in detection efficiency compared to plastic scintillator beta cells. Due to the uncertainty on the impact of the competing variables, we have developed a figure-of-merit (FOM) capable of determining the impact of detector parameters on the MDAs. By utilizing the FOM to analyze different detectors, we are able to directly compare current and future detectors and estimate their impact on the radioxenon MDAs.
Park, Lora E; Kondrak, Cheryl L; Ward, Deborah E; Streamer, Lindsey
People often search for cues in the environment to determine whether or not they will be judged or treated negatively based on their social identities. Accordingly, feedback from gatekeepers-members of majority groups who hold authority and power in a field-may be an especially important cue for those at risk of experiencing social identity threat, such as women in math settings. Across a series of studies, women who received positive ("Good job!") versus objective (score only) feedback from a male (vs. female) authority figure in math reported greater confidence; belonging; self-efficacy; more favorable Science, Technology, Engineering, and Mathematics (STEM) attitudes/identification/interest; and greater implicit identification with math. Men were affected only by the type of math feedback they received, not by the source of feedback. A meta-analysis across studies confirmed results. Together, these findings suggest that positive feedback from gatekeepers is an important situational cue that can improve the outcomes of negatively stereotyped groups.
Takacs, P.Z.; Church, E.L.
Most metal mirrors currently used in synchrotron radiation (SR) beam lines to reflect soft x-rays are made of electroless nickel plate on an aluminum substrate. This material combination has allowed optical designers to incorporate exotic cylindrical aspheres into grazing incidence x-ray beam-handling systems by taking advantage of single-point diamond machining techniques. But the promise of high-quality electroless nickel surfaces has generally exceeded the performance. We will examine the evolution of electroless nickel surfaces through a study of the quality of mirrors delivered for use at the National Synchrotron Light Source over the past seven years. We have developed techniques to assess surface quality based on the measurement of surface roughness and figure errors with optical profiling instruments. It is instructive to see how the quality of the surface is related to the complexity of the machine operations required to produce it
Mariana Resende Côrrea
Full Text Available Art as process and reflection of the lived moment deals many times with issues that refers to its context and with the available materials in the current scenario. In a society marked by consumption and ephemerality, this article promotes a reflection on the use of disposed and collected products in works of visual artists. The bricoleur appears in this context as a central figure for the understanding and the analysis of some of the many artistic practices realized recently. By bricolage, artists like Joseph Cornell, Farnese de Andrade, Amanda Mei and Courtney Smith performed works with hybrid content that reflect the lived moment and issues contained in the materials available in the current scenario.
AUTHOR|(CDS)2083258; Rossini, Stefano; Le Godec, Gilles; Papastergiou, Konstantinos; Carrica, Daniel; Retegui, Rogeli Garcia
In some applications, like those for particle accelerators and transfer lines, electromagnet loads operate in cycling mode i.e. absorbing or extracting energy from or to a power source. Built-in energy storage such as electrochemical capacitors can be used whose lifetime is heavily depended on the current ripple and depth of discharge. Moreover, the sizing of this storage element is a trade-off between power taken from the grid and energy stored. Additionally, the adopted power conversion structure and control strategy impact on such decision process. In this work, a number of topologies have been evaluated for these applications and the key metrics used to compare them. The proposed figures of merit are used through examples to highlight the trade-offs related with the choice of dc-bus regulation topology and control strategy.
Each year, CDC Climate Research publishes in partnership with the French Ministry of Ecology, Sustainable Development, Transport and Housing (MEDDTL) the Key Figures on Climate - France and Worldwide, in the Highlights Series. This publication aims at gathering all the relevant data relating the scientific analysis of climate change, greenhouses gas emissions, in particular CO 2 emissions linked to energy use, and the emissions reduction-targeted economic policies. Contents: Part 1 - Climate Change: The Greenhouse Effect - Humans and the Greenhouse Effect - Stocks and Flows of GHGs: The Example of CO 2 - Increase in Atmospheric GHG Levels - Concentrations and Temperatures - Global Warming - Warming Differentiated by Latitude - Consequences of Global Warming. Part 2 - Greenhouse Gas Emissions: Snapshot of Global GHG Emissions - European Panorama of GHGs - French Panorama of GHGs. Part 3 - Energy-related CO 2 Emissions in the World: Energy-related CO 2 emissions - CO 2 Emissions due to Electricity Production including CHP Plants - CO 2 Emission Factors. Part 4 - CO 2 Emissions by Sector in Europe and in France: Fuel Combustion: the Largest Emitter of CO 2 - CO 2 Emissions due to Energy Production and Conversion - Transportation-related CO 2 Emissions - Industry-related CO 2 Emissions - CO 2 Emissions in the Other Sectors - CO 2 Emissions excluding Fuel Combustion. Part 5 - Climate Policies: The Kyoto Protocol - The Tradable Permit Market - Project Mechanisms of the Kyoto Protocol - Other Initiatives to Reduce Emissions - The European Union's Commitment - The European CO 2 Market (EU ETS) - The Carbon Price in the EU ETS - States Climate Policy: The Case of France. Practical information: CO 2 Key Figures - Glossary of Terms - Useful Links
Bullock, Erika C.
In this chapter, I use figure hiding as a metaphor representing the processes of exclusion and suppression that critical mathematics education (CME) seeks to address. Figure hiding renders identities and modes of thought in mathematics education and mathematics education research invisible. CME has a commitment to addressing figure hiding by…
Drechsel, Robert E.; Moon, Deborah
Since 1974, when the Supreme Court concluded in "Gertz v. Robert Welch, Inc." that public figures and private figures deserve different treatment under libel law (with private figures needing a lower standard of proof), most lower courts have had to sort out the two categories. From the results in "Gertz" and other cases, three…
Mariotti, Maria Alessandra
Discusses geometrical reasoning in the framework of the theory of Figural Concepts to highlight the interaction between the figural and conceptual components of geometrical concepts. Examples of students' difficulties and errors in geometrical reasoning are interpreted according to the internal tension that appears in figural concepts resulting…
Rudd, Lynn L.
Adolescents use literacies in order to build identities in a variety of figured worlds. Some identities become more powerful than others as adolescents attempt to understand and successfully utilize the valuations and literacies of the diverse figured worlds in which they participate. The goals of this study were to describe the figured worlds of…
Linguistics has long recognised that figurative language in the form of metaphorical expressions structures and communicates attitudes towards the ideas and concepts being expressed and that multilingual students also employ linguistic figures frequently in their writing. In this study, multilingual students use figurative language to both…
Wokke, Martijn E; Sligte, Ilja G; Steven Scholte, H; Lamme, Victor A F
The ability to distinguish a figure from its background is crucial for visual perception. To date, it remains unresolved where and how in the visual system different stages of figure-ground segregation emerge. Neural correlates of figure border detection have consistently been found in early visual cortex (V1/V2). However, areas V1/V2 have also been frequently associated with later stages of figure-ground segregation (such as border ownership or surface segregation). To causally link activity in early visual cortex to different stages of figure-ground segregation, we briefly disrupted activity in areas V1/V2 at various moments in time using transcranial magnetic stimulation (TMS). Prior to stimulation we presented stimuli that made it possible to differentiate between figure border detection and surface segregation. We concurrently recorded electroencephalographic (EEG) signals to examine how neural correlates of figure-ground segregation were affected by TMS. Results show that disruption of V1/V2 in an early time window (96-119 msec) affected detection of figure stimuli and affected neural correlates of figure border detection, border ownership, and surface segregation. TMS applied in a relatively late time window (236-259 msec) selectively deteriorated performance associated with surface segregation. We conclude that areas V1/V2 are not only essential in an early stage of figure-ground segregation when figure borders are detected, but subsequently causally contribute to more sophisticated stages of figure-ground segregation such as surface segregation.
Wokke, M.E.; Sligte, I.G.; Scholte, H.S.; Lamme, V.A.F.
.The ability to distinguish a figure from its background is crucial for visual perception. To date, it remains unresolved where and how in the visual system different stages of figure-ground segregation emerge. Neural correlates of figure border detection have consistently been found in early visual
Palmer, Barbara C.; Sun, Lingzhi; Leclere, Judith T.
This article will analyze the figurative language that reflects Chinese traditional society and culture in "Yeh-Shen." The authors will consider both the figures of speech and the figures of thought (to include symbolism) that provide insight into an understanding of the Chinese culture through a reading of "Yeh-Shen." This analysis can be used by…
Supèr, Hans; Romeo, August
In the visual cortex, feedback projections are conjectured to be crucial in figure-ground segregation. However, the precise function of feedback herein is unclear. Here we tested a hypothetical model of reentrant feedback. We used a previous developed 2-layered feedforward spiking network that is able to segregate figure from ground and included feedback connections. Our computer model data show that without feedback, neurons respond with regular low-frequency (∼9 Hz) bursting to a figure-ground stimulus. After including feedback the firing pattern changed into a regular (tonic) spiking pattern. In this state, we found an extra enhancement of figure responses and a further suppression of background responses resulting in a stronger figure-ground signal. Such push-pull effect was confirmed by comparing the figure-ground responses with the responses to a homogenous texture. We propose that feedback controls figure-ground segregation by influencing the neural firing patterns of feedforward projecting neurons.
Full Text Available In the visual cortex, feedback projections are conjectured to be crucial in figure-ground segregation. However, the precise function of feedback herein is unclear. Here we tested a hypothetical model of reentrant feedback. We used a previous developed 2-layered feedforward spiking network that is able to segregate figure from ground and included feedback connections. Our computer model data show that without feedback, neurons respond with regular low-frequency (∼9 Hz bursting to a figure-ground stimulus. After including feedback the firing pattern changed into a regular (tonic spiking pattern. In this state, we found an extra enhancement of figure responses and a further suppression of background responses resulting in a stronger figure-ground signal. Such push-pull effect was confirmed by comparing the figure-ground responses with the responses to a homogenous texture. We propose that feedback controls figure-ground segregation by influencing the neural firing patterns of feedforward projecting neurons.
Eramudugolla, Ranmalee; Driver, Jon; Mattingley, Jason B
Unilateral spatial neglect is a disorder of attention and spatial representation, in which early visual processes such as figure-ground segmentation have been assumed to be largely intact. There is evidence, however, that the spatial attention bias underlying neglect can bias the segmentation of a figural region from its background. Relatively few studies have explicitly examined the effect of spatial neglect on processing the figures that result from such scene segmentation. Here, we show that a neglect patient's bias in figure-ground segmentation directly influences his conscious recognition of these figures. By varying the relative salience of figural and background regions in static, two-dimensional displays, we show that competition between elements in such displays can modulate a neglect patient's ability to recognise parsed figures in a scene. The findings provide insight into the interaction between scene segmentation, explicit object recognition, and attention.
White, Hannah; Jubran, Rachel; Heck, Alison; Chroust, Alyson; Bhatt, Ramesh S
In this study we sought to determine whether infants, like adults, utilize previous experience to guide figure/ground processing. After familiarization to a shape, 5-month-olds preferentially attended to the side of an ambiguous figure/ground test stimulus corresponding to that shape, suggesting that they were viewing that portion as the figure. Infants' failure to exhibit this preference in a control condition in which both sides of the test stimulus were displayed as figures indicated that the results in the experimental condition were not due to a preference between two figure shapes. These findings demonstrate for the first time that figure/ground processing in infancy is sensitive to top-down influence. Thus, a critical aspect of figure/ground processing is functional early in life.
Sekino, Masaki; Ohsaki, Hiroyuki; Takiyama, Yoshihiro; Yamamoto, Keita; Matsuzaki, Taiga; Yasumuro, Yoshihiro; Nishikawa, Atsushi; Maruo, Tomoyuki; Hosomi, Koichi; Saitoh, Youichi
Previously we proposed an eccentric figure-eight coil that can cause threshold stimulation in the brain at lower driving currents. In this study, we performed numerical simulations and magnetic stimulations to healthy subjects for evaluating the advantages of the eccentric coil. The simulations were performed using a simplified spherical brain model and a realistic human brain model. We found that the eccentric coil required a driving current intensity of approximately 18% less than that required by the concentric coil to cause comparable eddy current densities within the brain. The eddy current localization of the eccentric coil was slightly higher than that of the concentric coil. A prototype eccentric coil was designed and fabricated. Instead of winding a wire around a bobbin, we cut eccentric-spiral slits on the insulator cases, and a wire was woven through the slits. The coils were used to deliver magnetic stimulation to healthy subjects; among our results, we found that the current slew rate corresponding to motor threshold values for the concentric and eccentric coils were 86 and 78 A/µs, respectively. The results indicate that the eccentric coil consistently requires a lower driving current to reach the motor threshold than the concentric coil. Future development of compact magnetic stimulators will enable the treatment of some intractable neurological diseases at home. © 2014 Wiley Periodicals, Inc.
In 2 studies, children ages 3 to 7 years were asked to recall a series of touches that occurred during a previous staged event. The recall interview took place 1 week after the event in Study 1 and immediately after the event in Study 2. Each recall interview had 2 sections: In 1 section, children were given human figure drawings (HFDs) and were asked to show where the touching took place; in the other section, the same questions were asked without the HFDs (verbal condition). Children were randomly assigned to 2 different conditions: HFD 1st/verbal 2nd or verbal 1st/HFD 2nd. There were 2 major findings. First, HFDs elicited more errors than the verbal condition when used to probe for information that the child had already been asked. Second, regardless of interview method, children had poor recall of the touches even when these occurred minutes before the interview. It is suggested that cognitive mechanisms involving memory and semantics underlie children's poor recall of touching in both verbal and HFD conditions. Copyright 2009 APA
In 2 studies, children ages 3 to 7 years were asked to recall a series of touches that occurred during a previous staged event. The recall interview took place 1 week after the event in Study 1 and immediately after the event in Study 2. Each recall interview had 2 sections: In 1 section, children were given human figure drawings (HFDs) and were asked to show where the touching took place; in the other section, the same questions were asked without the HFDs (verbal condition). Children were randomly assigned to 2 different conditions: HFD 1st/verbal 2nd or verbal 1st/HFD 2nd. There were 2 major findings. First, HFDs elicited more errors than the verbal condition when used to probe for information that the child had already been asked. Second, regardless of interview method, children had poor recall of the touches even when these occurred minutes before the interview. It is suggested that cognitive mechanisms involving memory and semantics underlie children’s poor recall of touching in both verbal and HFD conditions. PMID:20025421
Full Text Available Learning idioms which is considered a very essential part of learning and using language (Sridhar and Karunakaran, 2013 has recently attracted a great attention of English learning researchers particularly the assessment of how well Asian language learners acquire and use idioms in communication (Tran, 2013. Understanding and using them fluently could be viewed as a sign towards language proficiency as they could be an effective way to give students better conditions to enhance their communication skills in the daily context (Beloussova, 2015. Investigating how idiomatic expressions are dealt with and processed in a second language or foreign language is an issue worth examining further since it may give language teachers a better idea of some of the strategies language learners use in order to interpret figurative language. Despite their importance, learning and using English idioms by Arab EFL learners have not been investigated extensively, and no research has been conducted on Jordanian students’ idiomatic competency. Thus, the researcher decided to work on these un-tackled issues in the Jordanian context. Most idioms-based investigations are the difficulties Jordanians learners of English face when translating them into Arabic (Hussein, Khanji, and Makhzoumi, 2000; Bataineh and Bataineh, 2002; Alrishan and Smadi, 2015. The analysis of the test showed students’ very poor idiomatic competence; particularly a very limited awareness of the most frequently used idioms despite their overwhelming desire to learn them. Data analysis of the questionnaire revealed the strategies students use and the problems they face in understanding and learning idioms.
Tomihara, Mitsuo (Kinki Univ., Osakasayama, Osaka (Japan). School of Medicine)
CT scan is widely used in orthopedic examinations. By three-dimentional display of the form of bone and joint, the change of form can be identified and the lesion can be located. CT figures were stereographically processed using a personal computer to display the images of the hip joints. The outlines of the bone seen on the CT film were directly traced with a digitizer, then the A/D converted coordinate data were obtained. The data for each slice were input to the personal computer. After conversion to normal coordinate and magnification, the data were filed on the floppy disc. These data were regained from the disk and made affin transformation to display the stereographic images of the hip joints. In a case of solitary bone cyst of the coxal bone, this method helped us to decide the appropriated surgical approach. For the congenital dysplasia of the hip, acetabular coverage was examined three-dimensionally and postoperative changes were assessed in the cases of shelf operation and intertrochanteric extension osteotomy. In the cases of aseptic necrosis of the femoral head, location and size of the necrotic area were clearly visualized and the appropriate surgical procedure could be decided. Moreover, it was useful to decide the degree of rotation of the femoral head in rotational osteotomy. (author) 61 refs.
Lagro-Janssen, Toine; Grosicar, Janja
Trauma prevention starts with to find out the extent of the problem and who it affects. Insight into morbidity figures is therefore necessary. To explore sex differences in traumatology and secondary medical care utilization in primary care related to age and socio-economic status (SES). Data were obtained from an academic continuous morbidity registration project in the Netherlands in the period from 1996 to 2006, in which 13,000 patients were followed in 10 successive years. Sex differences showed a male excess from childhood to 45 years and women showing almost double trauma rates in the elderly. Low SES was associated with the greatest incidence of traumas. The largest sex difference in incidence above 65 years appeared in the high SES with more traumas in women compared with men. From this age on, female morbidity in traumatology outnumbered male morbidity regardless of SES. Considering use of referrals, we found that in the age group 15-45 years men made a greater use of secondary medical care. However, the vastest gender influence in medical care utilization was noticed in the age group over 65 years, outnumbered with women. Young men and old women are the most at risk for traumatic health problems: men presenting with traumata of the skull, the tibia and ocular trauma's and women with fractures of the femur, humerus and wrist. For both men and women the greatest incidence is in the low SES. Family physicians can play a pivotal role in prevention to focus on their patients with high risks.
Full Text Available The article concerns itself with the figure of the teacher in Estonian society. We do not concentrate on the educational system as a whole, but on one specific and crucial element in this apparatus - the teacher. We begin by offering a brief historical overview of the conditions of pedagogues in the 20th century before moving on to describe the adoption of neo-liberal free market policies since the 1990s and the effects these policies had and still have on education. Our main concern is to understand the teacher as an actor in power relations; to achieve this understanding we have selected as our examples 1 surveillance techniques in school environment that have direct relations to the state and the market; and 2 the 2012 educational workers' strike that made it quite clear that the teachers have been fixed to a position of wage workers. The overall and more abstract aim of the paper is to think about the social role of the teacher in Estonia.
Meloy, J Reid; James, David V; Mullen, Paul E; Pathé, Michele T; Farnham, Frank R; Preston, Lulu F; Darnley, Brian J
Detailed comparison of factors associated with abnormal approach to the prominent and with escalation from communication to approach has not hitherto been undertaken. This partially reflects the failure of individual studies to adopt compatible terminologies. This study involves a careful dissection of six public figure studies, three involving U.S. politicians, two Hollywood celebrities, and one the British Royal Family. Common findings were unearthed across six headings. Approachers were significantly more likely to exhibit serious mental illness, engage in multiple means of communication, involve multiple contacts/targets, and to incorporate into their communication requests for help. They were significantly less likely to use threatening or antagonistic language in their communications, except in those cases involving security breaches. These results emphasize the importance of integrating mental health findings and preventive measures into risk management. Approach should not be regarded as a single behavioral category and has multiple motivations. Future studies should adopt standard terminology, preferably taken from the general stalking research. © 2010 American Academy of Forensic Sciences.
Tatiana de Cássia Nakano
Full Text Available Com o objetivo de investigar evidências de validade do Teste de Criatividade Figural Infantil, instrumento que visa avaliar 12 características criativas (Fluência, Flexibilidade, Elaboração, Originalidade, Expressão de Emoção, Perspectiva Incomum, Perspectiva Interna, Fantasia, Movimento, Uso de Contexto, Extensão de Limites e Títulos Expressivos, uma análise fatorial foi realizada visando uma melhor compreensão acerca do agrupamento dessas características. Estudantes de 1a a 8a séries do Ensino Fundamental (n=1253, 599F / 654M responderam ao instrumento. A análise fatorial apontou uma estrutura composta por quatro fatores (enriquecimento de idéias, aspectos cognitivos, emotividade e preparação criativa, que foi adotado como modelo de interpretação do instrumento devido à sua consistência com a literatura científica.
Hestroffer, D.; Tanga, P.; Richardson, D. C.; Berthier, J.; Cellino, A.; Durech, J.; Michel, P.
Since their formation, asteroids since their formation have experienced little physical, geological or thermal evolution. Like comets they are thought to be among the most pristine remnants of the early solar system. One physical process, however, has played a major role since the ancient times: collisions. Dynamical families were produced by catastrophic collisions involving large enough energy to break the parent body. Other lines of evidence suggest that catastrophic collisions can also produce rubble-piles, i.e., loosely bound of post-collisional aggregates that re-accumulate to form a single body, and are kept together by gravity. The main objective of this work is to understand if—and under what conditions—Jacobi ellipsoids or other equilibrium figures can be obtained naturally by this way. This is done by performing numerical experiments simulating the re-accumulation process, and by performing high-angular resolution observations in order to better constrain the shape and density of the targets. It is shown that the outcomes of reaccumulation events tend to produce a rather narrow variety of possible shapes, and in some cases also binary systems.
Full Text Available This article discusses the methodological implications of using a figurational approach to the study of Gaelic games (the Irish sports of hurling and Gaelic football and their organisation and governance from the late nineteenth century onwards. Following Norbert Elias, we argue that data generation guided by theories, and potentially modifying such theories, are essential components of research endeavours. The problem of generalisation or representativeness of historical documents can be addressed by treating documents as part of a fi guration of evidence, thereby constituting a mutually supporting network of data that serves as a scaffold or structure for theoretical and empirical findings. Based on the experience of using documents such as newspaper and referee reports of matches, and also organisational documents such as the minutes of meetings at various levels of governance, we contribute to the discussion concerning borders and boundary maintenance between history, sociology and historical sociology. While we elaborate on the Eliasian perspective on emotional detachment, and secondary involvement, when conducting research, we also note the dificulties in avoiding ‘preferred’ readings of national history given that Gaelic games have been intertwined with the narrative and project of national self-determination in Ireland. Researchers are compelled to recognise the theoretical significance of sports as a motor and symbol of emotional identifications, but must also create distance from their own national habitus in order to prioritise participation in intergenerational knowledge generation over further national myth-making.
This document makes a synthesis on the climate in France and in the World. Contents: 1 - Climate Change: The Greenhouse Effect, Humans and the Greenhouse Effect, Stocks and Flows of GHGs: The Example of CO 2 , Increase in Atmospheric GHG Levels, Concentrations and Temperatures, Global Warming, Warming Differentiated by Latitude, Consequences of Global Warming; 2 - Greenhouse Gas Emissions Snapshot of Global GHG Emissions, European Panorama of GHGs, French Panorama of GHGs; 3 - Energy-related CO 2 Emissions in the World: 3.1 Energy-related CO 2 emissions, CO 2 Emissions due to Electricity Production including CHP Plants, CO 2 Emission Factors; 4 - CO 2 Emissions by Sector in Europe and in France: Fuel Combustion: the Largest Emitter of CO 2 , CO 2 Emissions due to Energy Production and Conversion, Transportation-related CO 2 Emissions, Industry-related CO 2 Emissions, CO 2 Emissions in the Other Sectors, CO 2 Emissions excluding Fuel Combustion; 5 - Climate Policies: The Kyoto Protocol, The Tradable Permit Market, Project Mechanisms of the Kyoto Protocol, The European Union's Commitment, European CO 2 Market (EU ETS), Towards a Price Signal for CO 2 Emissions, States Climate Policy: The Case of France, Other Initiatives to Reduce Emissions; 6 - Practical information: CO 2 Key Figures, Glossary of Terms, Useful Links
Craft, Edward; Schütze, Hartmut; Niebur, Ernst; von der Heydt, Rüdiger
Psychophysical studies suggest that figure-ground organization is a largely autonomous process that guides--and thus precedes--allocation of attention and object recognition. The discovery of border-ownership representation in single neurons of early visual cortex has confirmed this view. Recent theoretical studies have demonstrated that border-ownership assignment can be modeled as a process of self-organization by lateral interactions within V2 cortex. However, the mechanism proposed relies on propagation of signals through horizontal fibers, which would result in increasing delays of the border-ownership signal with increasing size of the visual stimulus, in contradiction with experimental findings. It also remains unclear how the resulting border-ownership representation would interact with attention mechanisms to guide further processing. Here we present a model of border-ownership coding based on dedicated neural circuits for contour grouping that produce border-ownership assignment and also provide handles for mechanisms of selective attention. The results are consistent with neurophysiological and psychophysical findings. The model makes predictions about the hypothetical grouping circuits and the role of feedback between cortical areas.
Full Text Available Cultural memory is the starting point for studying culture. Theatre, on the other hand, is a multidimensional play with memory; it is an emblem of a certain culture, and of the overall blending of various discourses within it. Hence the relation between theatre and memory is rather complex and multifaceted. Theatre is a medium synthesising text and performance, speech and gesture (play, acting, as well as establishing direct, at least doubly articulated communication: among the actors on stage on the one hand, and between the actors and the audience on the other. They are all subjects of theatrical memory. Theatre not only uses memory in order to create the plot, develop the characters or establish communication with the audience, but also becomes a figure of memory itself: a culturally modelled, socially mandated (iconic, narrative, etc. memory image (Assman. Additionally, theatre may be considered a place of memory, as well. But theatre is not a simple mnemonic of repeating reality—it is not merely a simulacrum, but also a quotation of reality; it does not aim to copy or memorise reality, but to represent it and interpret it critically. This is particularly true of the contemporary rough theatre of brutality.
While substantial progress in the efficiency of polymer-based solar cells was possible by optimizing the energy levels of the polymer and more recently also the acceptor molecule, further progress beyond 10% efficiency requires a number of criteria to be fulfilled simultaneously, namely, low energy-level offsets at the donor–acceptor heterojunction, low open-circuit voltage losses due to nonradiative recombination, and efficient charge transport and collection. In this feature article we discuss these criteria considering thermodynamic limits, their correlation to photocurrent and photovoltage, and effects on the fill factor. Each criterion is quantified by a figure of merit (FOM) that directly relates to device performance. To ensure a wide applicability, we focus on FOMs that are easily accessible from common experiments. We demonstrate the relevance of these FOMs by looking at the historic and recent achievements of organic solar cells. We hope that the presented FOMs are or will become a valuable tool to evaluate, monitor, and guide further development of new organic absorber materials for solar cells.
Stanzani Maserati, Michelangelo; D'Onofrio, Renato; Matacena, Corrado; Sambati, Luisa; Oppi, Federico; Poda, Roberto; De Matteis, Maddalena; Naldi, Ilaria; Liguori, Rocco; Capellari, Sabina
To study human figure drawing in a group of Alzheimer's disease (AD) patients and compare it with a group of patients with mild cognitive impairment (MCI) and controls. We evaluated consecutive outpatients over a one-year period. Patients were classified as affected by AD or by MCI. All patients and controls underwent a simplified version of the human-figure drawing test and MMSE. A qualitative and quantitative analysis of all human figures was obtained. 112 AD, 100 MCI patients and 104 controls were enrolled. AD patients drew human figures poor in details and globally smaller than MCI patients and controls. Human figures drawn by MCI patients are intermediate in body height between those of the AD patients and the healthy subjects. The head-to-body ratio of human figures drawn by AD patients is greater than controls and MCI patients, while the human figure size-relative-to-page space index is significantly smaller. Body height is an independent predictor of cognitive impairment correlating with its severity and with the number of the figure's details. Human figures drawn by AD patients are different from those drawn by healthy subjects and MCI patients. Human figure drawing test is a useful tool for orienting cognitive impairment's diagnosis.
Allen, C.; Cowan, R.; Divine, J.
The Radioactive Acid Digestion Test Unit (RADTU) has been constructed at Hanford to process combustible transuranic waste. Laboratory testing, pilot plant testing, engineering studies, and safety studies have been completed and incorporated in the system design. 44 figures, 7 tables
Aguilar, Millán; Muñoz-Guerra, Jesús; Plata, María Del Mar; Del Coso, Juan
Every year, the World Anti-Doping Agency (WADA) publishes the main statistics reported by the accredited laboratories, which provide very valuable information for assessing changes in the patterns of doping in sports over time. Using the information provided since 2003 as the basis for the analysis, the evolution of doping/anti-doping figures over the last decade can be examined in reasonable detail, at least in reference to samples analyzed and categories of substances more commonly found in athletes' samples. This brief analysis of the WADA statistical reports leads us to the following outcomes: the increase in anti-doping pressure from 2003 to 2015, as evidenced by increased numbers of samples analyzed and banned substances, has not directly produced a higher frequency of adverse/atypical findings. Although this could be interpreted as steady state in the capacity to detect doping through this whole period, it also resulted in a significant increase in the absolute number of samples catalogued as doping (from 2247 in 2003 to 5912 in 2015). Anabolic agents have been the most common doping substances detected in all statistics reports while the remaining groups of substances are much less frequently found in doping control samples. Given that one might have expected the enhancement of the anti-doping programme led by WADA over this last decade to have increased the percentage of adverse/atypical findings, the fact that it did not might indicate the need to take another step in sampling strategies, such as 'more intelligent testing' based on the differences in the prevalence of doping substances among sports. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.
Baude, Manuel; Dussud, Francois-Xavier; Ecoiffier, Mathieu; Moreau, Sylvain; Bottin, Anne; Duvernoy, Jerome; Vailles, Charlotte
In line with previous years, the 2018 edition of 'Key figures on climate' has been written in the context of the 22. Conference of the Parties on Climate Change (COP 22) held in Bonn from 6 to 17 November 2017. This latest version was updated relative to the 2017 edition. New data sources have been used for emissions factors and the part on the carbon footprint was further developed. The part on climate policies notably deals with the Paris Agreement adopted in December 2015 at COP 21. Several data sets, displayed in graphs in this document are also available in tables on the web version. Content: 1 - What is climate change? This part summarizes the scientific basis of climate change, including indicators, causes and possible consequences of global warming. 2 - Which amounts of greenhouse gases are emitted globally? The focus here is on the most relevant data related to global greenhouse gases (GHG) emissions, in particular the geographic distribution of these emissions. 3 - How much greenhouse gas is emitted in Europe and in France? A complete overview of GHG emissions statistics in Europe and in France is presented in this part as well as estimates of the carbon footprint of French people. 4 - What is the sectoral distribution of GHG emissions in Europe and in France? This part features the detailed evolution since 1990 of GHG emissions in the following economic sectors: energy sector, transports, industry, residential and tertiary, agriculture, forestry, land use and waste management. 5 - Which climate policies in the world, in Europe and in France? The main climate policies are described at each level: global, European and French
Elena G. Lapshina
Full Text Available In article activity of sign figures of the Russian vanguard of Vladimir Evgrafovich Tatlin, the first Soviet designer, and Efim Vladimirovich Ravdel, the first rector of the Highest state art and technical workshops is considered. The special attention is paid to the Penza period of their life. In 1905 Tatlin began the vocational education in Penza in Art school of N.D. Seliverstov upon termination of whom gained the diploma of the artist with the right of teaching drawing, drawing and calligraphy. During training he was admitted to school in Tsege's salon, participated in an exhibition of the third salon of the Golden Fleece magazine in Moscow. Then Tatlin moves to Moscow where arranges own workshop. Revolutionary events found Tatlin in St. Petersburg where he became the informal leader of «futurists». In April, 1918 he was appointed the chairman of the Moscow art board of Department FROM Narkompros. He taught in picturesque workshops of the Moscow and Petrograd Svomas. Ravdel since 1918 was the head of department of arts of Board of National education of the Penza provincial council of country and working deputies; I organized drama studio, national conservatory, the museum; I participated in exhibitions, debates, etc. In detail the reform of the Penza art school (1918-1920 which was carried out by it, attraction of pedagogical shots (D.P. Buryshkin, D.M. Iofan, etc., a set of entrants, etc. is considered; creation of an architectural workshop of the Penza free state art workshops. In 1920 Ravdel went to Moscow where held the rector's position of Highest state art and technical workshops (1920-1923.
Full Text Available Abstract Elite adolescent figure skaters must accommodate both the physical demands of competitive training and the accelerated rate of bone growth that is associated with adolescence, in this sport that emphasizes leanness. Although, these athletes apparently have sufficient osteogenic stimuli to mitigate the effects of possible low energy availability on bone health, the extent or magnitude of bone accrual also varies with training effects, which differ among skater disciplines. Purpose We studied differences in total and regional bone mineral density in 36 nationally ranked skaters among 3 skater disciplines: single, pairs, and dancers. Methods Bone mineral density (BMD of the total body and its regions was measured by dual energy x-ray absorptiometry (DXA. Values for total body, spine, pelvis and leg were entered into a statistical mixed regression model to identify the effect of skater discipline on bone mineralization while controlling for energy, vitamin D, and calcium intake. Results The skaters had a mean body mass index of 19.8 ± 2.1 and % fat mass of 19.2 ± 5.8. After controlling for dietary intakes of energy, calcium, and vitamin D, there was a significant relationship between skater discipline and BMD (p = 0.002, with single skaters having greater BMD in the total body, legs, and pelvis than ice dancers (p Conclusions Single and pair skaters have greater BMD than ice dancers. The osteogenic effect of physical training is most apparent in single skaters, particularly in the bone loading sites of the leg and pelvis.
Baude, Manuel; Dussud, Francois-Xavier; Ecoiffier, Mathieu; Duvernoy, Jerome; Vailles, Charlotte; Moreau, Sylvain; Bottin, Anne; Hiblot, Guillaume
In line with previous years, the 2017 edition of 'Key figures on climate' has been written in the context of the 22. Conference of the Parties on Climate Change (COP 22) held in Marrakech from 7 to 18 November 2016. This latest version, published as part of the new 'datalab' collection of the General commission for sustainable development was updated and expanded relative to the 2016 edition. New data sources have been used for the part on global CO_2 emissions. The part on climate policies was further developed, and notably deals with the Paris agreement adopted in December 2015 at COP 21. Moreover, the analysis of climate finance (current climate investments and climate finance needs) has been expanded. About the form, and with a goal of simplification, some data previously displayed in both a graph and a table is now presented only in a graph. Content: Part 1: What is climate change? This part summarizes the scientific basis of climate change, including indicators, causes and possible consequences of global warming. Part 2: Which amounts of greenhouse gases are emitted globally? The focus here is on the most relevant data related to global greenhouse gases (GHG) emissions, in particular the geographic distribution of these emissions. Part 3: How much greenhouse gas is emitted in Europe and in France? A complete overview of GHG emissions statistics in Europe and in France is presented in this part as well as estimates of the carbon footprint of French people. Part 4: What is the sectoral distribution of GHG emissions in Europe and in France? This part features the detailed evolution since 1990 of GHG emissions in the following economic sectors: energy sector, transports, industry, residential and tertiary, agriculture, forestry, land use and waste management. Part 5: Which climate policies in the world, in Europe and in France? The main climate policies are described at each level: global, European and French
Full Text Available Il Conformista di Moravia (1951, ambientato in epoca fascista, narra la vicenda di Marcello, membro dell’OVRA ossessionato dalla necessità di sentirsi uguale agli altri. Si tratta di un romanzo a tesi che lega l’omosessualità alla repressione e al fascismo. L’operazione di riscrittura di Bertolucci (1970 potenzia la chiave freudiana: sul grande schermo, la ferrea progressione temporale e causale del romanzo è scardinata attraverso un uso spregiudicato del flashback, mentre scompare ogni accenno al fato e Marcello diventa filtro dell'intera narrazione. La psicoanalisi rappresenta la chiave di volta che regge il film, sostituendo la meccanicità progressiva del fato con la bi-logica dell’inconscio. Per tacitare la propria omosessualità – non accettata a livello sociale ma, prima di tutto, dal protagonista stesso – Marcello tenta di conformarsi in tutto e per tutto alla società e al particolare momento storico-politico. Il matrimonio e l’adesione al fascismo sono i due strumenti di questa strategia di conformismo; le figure femminili, in particolare, attraverso un gioco di duplicazioni e rispecchiamenti, ricoprono un ruolo cardine, configurandosi ora come oggetto di un desiderio reale ora invece di un desiderio mediato dalla volontà di rimozione e negazione delle pulsioni non accettabili, dei ricordi indicibili e dei sensi di colpa. Giocando con l’immagine, il montaggio e le interferenze col sonoro, Bertolucci sembra suggerire infatti significati profondi, che contrastano con la superficie del testo, e proporre una particolare declinazione della “retorica freudiana” del testo: richiamandosi all’approccio critico psicanalitico offerto da Francesco Orlando, l’intervento indaga le manifestazioni semiotico-linguistiche della formazione di compromesso fra desiderio e negazione da parte del protagonista ed analizza alcuni momenti del film che riflettono simultaneamente le due forze psichiche in contrasto.
Aliyev, K; Aliyeva, G; Gadjiyeva, N
The aim of research is to study of the spirometry figures of bronchoobstructive syndrome in concomitant intestinal parasitosis. There are 81 patients aged from 5 to 61 years (male 43, female 38) were examined. The patients were divided into 2 groups: 1 group - patients treated only with bronchodilator therapy (14 patients with protozoa, 14 - with helminth, 12 - with combination of parasitosis); 2 group - patients treated with bronchodilator therapy in common with anti-parasitic therapy (14 patients with protozoa, 17 - with helminth, 10 - with combination of parasitosis). There are 22 patients with bronchoobstructive syndrome without parasites were included in control group. Functional disorders at the initial examination are not significantly distinguished between patients with protozoa, helminth, with combined parasitosis and patients without parasites. Considerable differences manifested in dynamics after treatment: only bronchodilator therapy of patients infected with parasites is not lead to sufficient increase of the indices of external respiration function, even the decreasing of the most parameters were observed in patients with helminth. The least growth of spirometric indices were observed in patients from group 1 - 2,17/ 5,09% predicted volumes (-6,81min; 10,54max), the highest growth were observed in patients from group 2 - 20,26/ 12,45% p.v. (2,77min; 43,85max). The spirographic indicators increase after treatment in the control group was more moderate in comparison with 1 and 2 groups - 5,96/ 2,97% p.v. (0,39min; 9,59max). Thus, using antiparasitic therapy in common with bronchodilator therapy in treatment of patients with intestinal parasitosis (group 2) is lead to the reliably significant positive dynamic of spirometry parameters in comparison not only to 1 group (<0,05 for many parameters) but also to control group (<0,01 for many parameters).
Simultaneous separation of five major ribonucleic acids by capillary electrophoresis with laser-induced fluorescence in the presence of electroosmotic flow: application to the rapid screening of 5S rRNA from ovarian cancer cells.
Shih, Ya-Chu; Liao, Ching-Ru; Chung, I-Che; Chang, Yu-Sun; Chang, Po-Ling
RNA integrity is important in RNA studies because poor RNA quality may impact downstream methodologies. This study proposes a rapid and cost-effective method for the determination of RNA integrity based on CE-LIF in the presence of electroosmotic flow. The proposed method uses poly(ethylene) oxide (Mavg=4,000,000 Da) as a sieving matrix for total RNA separation. Ethidium bromide (μg mL(-1)) was dissolved in a polymer solution as an interchelating dye for on-column fluorescent labeling. The 28S rRNA, 18S rRNA, 5.8S rRNA, 5S rRNA and tRNA from the total human RNA extracted from the cells were fully separated using the proposed method. The lowest detectable concentration of total RNA achieved was 100 pg μL(-1) with a 6 min sample injection followed by on-column concentration. In addition, the temperature-induced degradation of total RNA was observed by CE-LIF. The electropherograms revealed more fragmentation of 28S and 18S rRNAs by temperature-induced hydrolysis compared with the 5.8S rRNA, 5S rRNA and tRNA. Therefore, the results indicated that RNA degradation should be considered for long-term, high-temperature incubations in RNA-related experiments involving RNA hybridization. The proposed method is furthermore, applied to the determination of 5S rRNA overexpressed in ovarian cancer cells as compared to the cervical cancer cells. Overall, CE-LIF is highly promising for rapid screening of ovarian cancers without tedious pre-amplification steps. Copyright © 2014 Elsevier B.V. All rights reserved.
Insulin-like growth factor I (IGF-I) and long R(3) IGF-I differently affect development and messenger ribonucleic acid abundance for IGF-binding proteins and type IIGF receptors in in vitro produced bovine embryos
Motlík, Jan; Prelle, K.; Stojkovic, M.; Ewald, D.; Arnold, G. J.; Welf, E.
Roč. 142, - (2001), s. 1309-1316 ISSN 0013-7227 R&D Projects: GA ČR GV524/96/K162; GA AV ČR KSK5052113 Keywords : Insulin Like Growth Factor * bovine embryos Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.971, year: 2001
Luteinizing hormone (LH)-responsive Cushing's syndrome: the demonstration of LH receptor messenger ribonucleic acid in hyperplastic adrenal cells, which respond to chorionic gonadotropin and serotonin agonists in vitro
R.A. Feelders (Richard); W.W. de Herder (Wouter); S.W.J. Lamberts (Steven); L.J. Hofland (Leo); P.M. van Koetsveld (Peter); M. Verhoef-Post (Miriam); A.P.N. Themmen (Axel); F.H. de Jong (Frank); H.J. Bonjer (Jaap); A.J. Clark (Adrian); A-J. van der Lely (Aart-Jan)
textabstractIn a substantial part of adrenal adenomas and hyperplasias from patients with Cushing's syndrome, cortisol production is controlled by the expression of aberrant hormone receptors on adrenocortical cells. We present in vivo and in vitro data of two patients with a
Fraser, H M; Lunn, S F; Kim, H; Duncan, W C; Rodger, F E; Illingworth, P J; Erickson, G F
In the human menstrual cycle, extensive angiogenesis accompanies luteinization; and the process is physiologically important for corpus luteum (CL) function. During luteolysis, the vasculature collapses, and the endothelial cells die. In a conceptual cycle, the CL persists both functionally and structurally beyond the luteoplacental shift. Although luteal rescue is not associated with increased angiogenesis, endothelial survival is extended. Despite the central role of the luteal vasculature in fertility, the mechanisms regulating its development and demise are poorly understood. There is increasing evidence that insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) may be important effectors of luteal function. Here, we have found that IGFBP-3 messenger RNA is expressed in the endothelium of the human CL and that the levels of message change during luteal development and rescue by human CG. The signal was strong during the early luteal phase, but it showed significant reduction during the mid- and late luteal phases. Interestingly, administration of human CG caused a marked increase in the levels of IGFBP-3 messenger RNA in luteal endothelial cells that was comparable to that observed during the early luteal phase. We conclude that endothelial cell IGFBP-3 expression is a physiological property of the CL of menstruation and pregnancy. These observations raise the intriguing possibility that the regulated expression of endothelial IGFBP-3 may play a role in controlling angiogenesis and cell responses in the human CL by autocrine/paracrine mechanisms.
QUANTIFICATION OF RAINBOW TROUT (ONCORHYNCHUS MYKISS) ZONA RADIATA AND VITELLOGENIN MESSENGER RIBONUCLEIC ACID (MRNA) LEVELS USING REAL-TIME POLYMERASE CHAIN REACTION (PCR) AFTER IN VIVO TREATMENT WITH 17A-ESTRADIOL AND A-ZEARALENOL. (R826301)
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Concl...
Ohtsuka, E; Tanaka, T; Ikehara, M
E. Coli tRNAfMet fragments, C-G-C-G-Gp (bases 1-5), U-G-C-G-Gp (base 1 transition, analog) pG-G-C-G-Gp (base 1 transversion analog) and pG-G-s4U-G-Gp (bases 6-10) were synthesized by triester methods using 2'-O-(o-nitrobenzyl) nucleotides including a 3',5'-bisphosphorylated guanosine derivative. The s4U containing pentanucleotide was derived from the pG-G-C-G-Gp by treatment with liquid hydrogen sulfide. Images PMID:390499
M. van Kleffens (Marjolein); C.A.H. Groffen; N.F. Dits (Natasja); D.J. Lindenbergh-Kortleve (Dicky); A.G.P. Schuller (Alwin); S.L. Bradshaw; J.E. Pintar; E.C. Zwarthoff (Ellen); S.L.S. Drop (Stenvert); J.W. van Neck (Han)
textabstractThe insulin-like growth factor (IGF) system is an important regulator of fetal growth and differentiation. IGF bioavailability is modulated by IGF binding proteins (IGFBPs). We have generated six different antisera, directed to synthetic peptide fragments of
Supèr, Hans; Lamme, Victor A F
The visual system binds and segments the elements of an image into coherent objects and their surroundings. Recent findings demonstrate that primary visual cortex is involved in this process of figure-ground organization. In the primary visual cortex the late part of a neural response to a stimulus correlates with figure-ground segregation and perception. Such a late onset indicates an involvement of feedback projections from higher visual areas. To investigate the possible role of feedback in figure-ground perception we removed dorsal extra-striate areas of the monkey visual cortex. The findings show that figure-ground perception is reduced when the figure is presented in the lesioned hemifield and perception is normal when the figure appeared in the intact hemifield. In conclusion, our observations show the importance for recurrent processing in visual perception.
Full Text Available Figure-ground is the segmentation of visual information into objects and their surrounding backgrounds. Two main processes herein are boundary assignment and surface segregation, which rely on the integration of global scene information. Recurrent processing either by intrinsic horizontal connections that connect surrounding neurons or by feedback projections from higher visual areas provide such information, and are considered to be the neural substrate for figure-ground segmentation. On the contrary, a role of feedforward projections in figure-ground segmentation is unknown. To have a better understanding of a role of feedforward connections in figure-ground organization, we constructed a feedforward spiking model using a biologically plausible neuron model. By means of surround inhibition our simple 3-layered model performs figure-ground segmentation and one-sided border-ownership coding. We propose that the visual system uses feed forward suppression for figure-ground segmentation and border-ownership assignment.
Supèr, Hans; Romeo, August; Keil, Matthias
Figure-ground is the segmentation of visual information into objects and their surrounding backgrounds. Two main processes herein are boundary assignment and surface segregation, which rely on the integration of global scene information. Recurrent processing either by intrinsic horizontal connections that connect surrounding neurons or by feedback projections from higher visual areas provide such information, and are considered to be the neural substrate for figure-ground segmentation. On the contrary, a role of feedforward projections in figure-ground segmentation is unknown. To have a better understanding of a role of feedforward connections in figure-ground organization, we constructed a feedforward spiking model using a biologically plausible neuron model. By means of surround inhibition our simple 3-layered model performs figure-ground segmentation and one-sided border-ownership coding. We propose that the visual system uses feed forward suppression for figure-ground segmentation and border-ownership assignment.
Supèr, Hans; Romeo, August
In the visual cortex, feedback projections are conjectured to be crucial in figure-ground segregation. However, the precise function of feedback herein is unclear. Here we tested a hypothetical model of reentrant feedback. We used a previous developed 2-layered feedforwardspiking network that is able to segregate figure from ground and included feedback connections. Our computer model data show that without feedback, neurons respond with regular low-frequency (∼9 Hz) bursting to a figure-ground stimulus. After including feedback the firing pattern changed into a regular (tonic) spiking pattern. In this state, we found an extra enhancement of figure responses and a further suppression of background responses resulting in a stronger figure-ground signal. Such push-pull effect was confirmed by comparing the figure-ground responses withthe responses to a homogenous texture. We propose that feedback controlsfigure-ground segregation by influencing the neural firing patterns of feedforward projecting neurons. PMID:21738747
Peterson, M A; Harvey, E M; Weidenbacher, H J
Observers viewed upright and inverted versions of figure-ground stimuli, in which Gestalt variables specified that the center was figure. In upright versions, the surround was high in denotivity, in that most viewers agreed it depicted the same shape; in inverted versions, the surround was low in denotivity. The surround was maintained as figure longer and was more likely to be obtained as figure when the stimuli were upright rather than inverted. In four experiments, these effects reflected inputs to figure-ground computations from orientation-specific shape representations only. To account for these findings, a nonratiomorphic mechanism is proposed that enables shape recognition processes before figure-ground relationships are determined.
Full Text Available Among the problems faced by the constructors of clothing goods are the non-standard figures of the human body. The present article examines the possibilities of modifying the curve of women’s trousers. The author proposes methods of changing the basic drawing of the women’s trousers for figures with non-standard figures and to use these methods in the process of training in specialized educational institutions.
Oliver W. Layton; Ennio eMingolla; Arash eYazdanbakhsh
Determining whether a region belongs to the interior or exterior of a shape (figure-ground segregation) is a core competency of the primate brain, yet the underlying mechanisms are not well understood. Many models assume that figure-ground segregation occurs by assembling progressively more complex representations through feedforward connections, with feedback playing only a modulatory role. We present a dynamical model of figure-ground segregation in the primate ventral stream wherein feedba...
Vargas-Alfredo, Nelson; Dorronsoro, Ane; Cortajarena, Aitziber L; Rodríguez-Hernández, Juan
We describe herein a novel strategy for the fabrication of efficient 3D printed antibacterial scaffolds. For this purpose, both the surface topography as well as the chemical composition of 3D scaffolds fabricated by additive manufacturing were modified. The scaffolds were fabricated by fused deposition modeling (FDM) using high-impact polystyrene (HIPS) filaments. The surface of the objects was then topographically modified providing materials with porous surfaces by means of the Breath Figures approach. The strategy involves the immersion of the scaffold in a polymer solution during a precise period of time. This approach permitted the modification of the pore size varying the immersion time as well as the solution concentration. Moreover, by using polymer blend solutions of polystyrene and polystyrene-b-poly(acrylic acid) (PS 23 -b-PAA 18 ) and a quaternized polystyrene-b-poly(dimethylaminoethyl methacrylate) (PS 42 -b-PDMAEMAQ 17 ), the scaffolds were simultaneously chemically modified. The surfaces were characterized by scanning electron microscopy and infrared spectroscopy. Finally, the biological response toward bacteria was explored. Porous surfaces prepared using quaternized PDMAEMA as well as those prepared using PAA confer antimicrobial activity to the films, i.e., were able to kill on contact Staphylococcus aureus employed as model bacteria.
Self, Matthew W; Mookhoek, Aart; Tjalma, Nienke; Roelfsema, Pieter R
Figure-ground segregation is an important step in the path leading to object recognition. The visual system segregates objects ('figures') in the visual scene from their backgrounds ('ground'). Electrophysiological studies in awake-behaving monkeys have demonstrated that neurons in early visual areas increase their firing rate when responding to a figure compared to responding to the background. We hypothesized that similar changes in neural firing would take place in early visual areas of the human visual system, leading to changes in the perception of low-level visual features. In this study, we investigated whether contrast perception is affected by figure-ground assignment using stimuli similar to those in the electrophysiological studies in monkeys. We measured contrast discrimination thresholds and perceived contrast for Gabor probes placed on figures or the background and found that the perceived contrast of the probe was increased when it was placed on a figure. Furthermore, we tested how this effect compared with the well-known effect of orientation contrast on perceived contrast. We found that figure-ground assignment and orientation contrast produced changes in perceived contrast of a similar magnitude, and that they interacted. Our results demonstrate that figure-ground assignment influences perceived contrast, consistent with an effect of figure-ground assignment on activity in early visual areas of the human visual system. © 2015 ARVO.
Any polycrystalline aggregate normally has a preferred crystallographic orientation, or texture which depends on its thermal and or mechanical history. Preferred orientation is best described by means of a pole figure. A pole figure is a stereographic projection which shows the variation in pole density with pole orientation, for a selected set of crystal planes. In this work, computer programs was developed to plot pole figures. The corrected intensities are calculated and directly transmitted to the plotter. The different intensities levels are represented by different colors in the pole figure. (author)
Paola Basso Menna Barreto Gomes Zordan
Full Text Available As mulheres que tanto a história como a imaginação popular mitificaram como "bruxas" constituem figuras que expurgam as fobias da Contra Reforma. As bruxas foram torturadas e queimadas para sinalizar os perigos de práticas e saberes à margem da Igreja e de outras instituições dominantes na Idade Moderna. Parteiras, curandeiras e carpideiras, as bruxas misturam em seu caldeirão os mistérios da vida e da morte herdados das tradições pagãs. Este artigo percorre textos de historiadores, em especial o de Jules Michelet, que no século XIX construiu a imagem romântica e martirizada da bruxa, e o manual de inquisidores do século XIV, o Malleus Maleficarum, que descreve os poderes da bruxa, sua aliança com o demônio e sua ameaça para o cristianismo. Os discursos instaurados por tais textos constroem tanto a imagem que glorifica a bruxa quanto aquela que a execra, mostrando ambas o potencial transformador de suas práticas e de sua ligação com a sexualidade.The women whom history and popular imagination mythicized as "witches" constitute figures that purge the phobias of the Counter Reformation. Witches were tortured and burned to signal the dangers of practices and knowledge in the margins of the Church and other dominant institutions in the Modern Age. Midwives, healers and weepers, the witches blend in their large kettle the mysteries of life and death inherited from pagan traditions. This paper examines some historians' texts, especially that of Jules Michelet, who created the witch's romantic and martyred image, and the inquisitors' manual Malleus Maleficarum, that describes the witch's powers, her alliance with the demon and her threat to Christianity. These texts establish, through their different discourses, two opposing images: one that glorifies witches and another that execrates them, in order to show the transforming potential of their practices and their connection with sexuality.
Trisna Dinillah Harya
Full Text Available The title of this study is, “An Analysis of Figurative Languages Used in Paulo Coelho’s novel Entitled “The Alchemist”. The objectives of the study are to describe the types of the figurative language found in the book and to identify the contextual meaning of the figurative language. The method used in collecting the data related to the subject of this research is documentation method because the researcher collected the data from novel. This study was conducted by collecting any relevant data and information about the topic or problem of the study from novels and internet that are available for the analysis. The data collection used the following steps: reading the novel, and then selecting the data that used the types of figurative language. While the steps to analyze the data are identifying the types of figurative language according to Leech, identifying the contextual meaning of the figurative language, and the last is interpreting the data.The result shows that there are 70 sentences that have figurative language. From all the sentences, there are 30 items or 42.9% of simile, 27 items or 38.6% of personification, 12 items or 17.1% of metaphor, and 1 item or 1.4% of hyperbole. It can be indicated that the dominant type of figurative language in the novel is simile. The author uses simile to explain circumstances, to describe the characters, to express emotion of the characters, and to make his writing more vivid and entertaining. It can be concluded that figurative language has important roles in this novel. That‘s why the author used so many sentences that have figurative language in this novel. Using figurative language makes the novel more interesting to read, and helps the readers to imagine the story, the character based on the illustration that the author has already given in the story.
Trepanier, Mary L.; Liben, Lynn S.
A set of studies investigated the relative importance of operative schemes and figurative (rote) memory. In Study I, 60 concrete operational children from grades 1-4 were asked to reconstruct two types of stimuli from memory. In order to separate the effects of operative and figurative skill use, learning disabled children with poor figurative…
... 47 Telecommunication 1 2010-10-01 2010-10-01 false Example of Ideal EPIRB Spectrum 3 Figure 3 to Subpart N of Part 2 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL FREQUENCY ALLOCATIONS AND... Position Indicating Radiobeacons (EPIRBs) Pt. 2, Subpt. N, Fig. 3 Figure 3 to Subpart N of Part 2—Example...
Gene-list view of genomic data. The gene-list view allows users to compare data across a set of loci. The data in this figure includes copy number, mutation, and clinical data from 202 glioblastoma samples from TCGA. Adapted from Figure 7; Thorvaldsdottir H et al. 2012
Genovese, Jeremy E C
The Flynn effect is the long-term trend for scores on tests of cognitive ability to increase across cohorts. Several samples of children's human figure drawings, published in 1902, 1926, 1963, and 1968, are examined for evidence of a Flynn effect. Results show that larger percentages of children draw more complete human figures over the course of the 20th century.
Riggs, Kevin J.; Jolley, Richard P.; Simpson, Andrew
We investigated the role of inhibitory control in young children's human figure drawing. We used the Bear-Dragon task as a measure of inhibitory control and used the classification system devised by Cox and Parkin to measure the development of human figure drawing. We tested 50 children aged between 40 and 64 months. Regression analysis showed…
Dillen, Claudia; Steyaert, Jean; Op de Beeck, Hans P.; Boets, Bart
The embedded figures test has often been used to reveal weak central coherence in individuals with autism spectrum disorder (ASD). Here, we administered a more standardized automated version of the embedded figures test in combination with the configural superiority task, to investigate the effect of contextual modulation on local feature…
... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Flooring Radiant Tester Schematic Side Elevation 3 Figure 3 to Subpart A of Part 1209 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION.... 1209, Subpt. A, Fig. 3 Figure 3 to Subpart A of Part 1209—Flooring Radiant Tester Schematic Side...
Bunker, Matthew D.; Tobin, Charles D.
Contributes to journalistic legal scholarship and theory by examining the development of "public figure" status in defamation law, with particular attention to public figures who may have achieved notoriety among less than a national audience. Argues that trends in media and audience fragmentation warrant extensions of current doctrine based on…
Grant, Lynn E.
This article outlines criteria to define a figurative idiom, and then compares the frequent figurative idioms identified in two sources of spoken American English (academic and contemporary) to their frequency in spoken British English. This is done by searching the spoken part of the British National Corpus (BNC), to see whether they are frequent…
Self, Matthew W; Mookhoek, Aart; Tjalma, Nienke; Roelfsema, Pieter R
Figure-ground segregation is an important step in the path leading to object recognition. The visual system segregates objects ('figures') in the visual scene from their backgrounds ('ground'). Electrophysiological studies in awake-behaving monkeys have demonstrated that neurons in early visual
Self, M.W.; Mookhoek, A.; Tjalma, N.; Roelfsema, P.R.
Figure-ground segregation is an important step in the path leading to object recognition. The visual system segregates objects ('figures') in the visual scene from their backgrounds ('ground'). Electrophysiological studies in awake-behaving monkeys have demonstrated that neurons in early visual
Straube, Sirko; Fahle, Manfred
Although figure-ground segregation in a natural environment usually relies on multiple cues, we experience a coherent figure without usually noticing the individual single cues. It is still unclear how various cues interact to achieve this unified percept and whether this interaction depends on task demands. Studies investigating the effect of cue combination on the human EEG are still lacking. In the present study, we combined psychophysics, ERP and time-frequency analysis to investigate the interaction of orientation and spatial frequency as visual cues in a figure detection task. The figure was embedded in a matrix of Gabor elements, and we systematically varied figure saliency by changing the underlying cue configuration. We found a strong correlation between the posterior P2 amplitude and the perceived saliency of the figure: the P2 amplitude decreased with increasing saliency. Analogously, the power of the theta-band decreased for more salient figures. At longer latencies, the posterior P3 component was modulated in amplitude and latency, possibly reflecting increased decision confidence at higher saliencies. In conclusion, when the cue composition (e.g. one or two cues) or cue strength is changed in a figure detection task, first differences in the electrophysiological response reflect the perceived saliency and not directly the underlying cue configuration.
Teki, Sundeep; Chait, Maria; Kumar, Sukhbinder; von Kriegstein, Katharina; Griffiths, Timothy D
Auditory figure-ground segregation, listeners' ability to selectively hear out a sound of interest from a background of competing sounds, is a fundamental aspect of scene analysis. In contrast to the disordered acoustic environment we experience during everyday listening, most studies of auditory segregation have used relatively simple, temporally regular signals. We developed a new figure-ground stimulus that incorporates stochastic variation of the figure and background that captures the rich spectrotemporal complexity of natural acoustic scenes. Figure and background signals overlap in spectrotemporal space, but vary in the statistics of fluctuation, such that the only way to extract the figure is by integrating the patterns over time and frequency. Our behavioral results demonstrate that human listeners are remarkably sensitive to the appearance of such figures. In a functional magnetic resonance imaging experiment, aimed at investigating preattentive, stimulus-driven, auditory segregation mechanisms, naive subjects listened to these stimuli while performing an irrelevant task. Results demonstrate significant activations in the intraparietal sulcus (IPS) and the superior temporal sulcus related to bottom-up, stimulus-driven figure-ground decomposition. We did not observe any significant activation in the primary auditory cortex. Our results support a role for automatic, bottom-up mechanisms in the IPS in mediating stimulus-driven, auditory figure-ground segregation, which is consistent with accumulating evidence implicating the IPS in structuring sensory input and perceptual organization.
Peterson, Mary A.; Gibson, Bradley S.
Three experiments with 29 college students and 8 members of a university community demonstrate that shape recognition processes influence perceived figure-ground relationships in 3-dimensional displays when the edge between 2 potential figural regions is both a luminance contrast edge and a disparity edge. Implications for shape recognition and…
Burkitt, Esther; Tala, Katri; Low, Jason
Recent research has shown that children use colors systematically in relation to how they feel about certain colors and the figures that they draw. This study explored cultural differences between Finnish and English children's use of color to represent figures with contrasting emotional characters. One hundred and eight children (54 Finnish, 54…
Naylor, Lauren; Van Herwegen, Jo
The current study investigated the development of figurative language production, including different types of figurative expressions, during a fictional narrative in 20 typically developing (TD) children and 20 children with Williams syndrome (WS) aged 7-18 years old. In contrast to previous studies, developmental trajectories showed that (1) the…
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Chang, Hua-Cheng; Chen, Hung-Yuan
Contemporary toy is characterized by accelerating social, cultural and technological change. An attractive action figure can grab consumers' attention, influence the latent consuming preference and evoke their pleasure. However, traditional design of action figure is always dependent on designer's opinion, subjective experience and preference. It…
Wong, Wing-Kwong; Yin, Sheng-Kai; Yang, Chang-Zhe
This paper presents a tool for drawing dynamic geometric figures by understanding the texts of geometry problems. With the tool, teachers and students can construct dynamic geometric figures on a web page by inputting a geometry problem in natural language. First we need to build the knowledge base for understanding geometry problems. With the…
Oleg V. Bisikalo
Full Text Available In this paper the search method based on usage of figurative indexation of folksonomic characteristics of graphical files is described. The method takes into account extralinguistic information, is based on using a model of figurative thinking of humans. The paper displays the creation of a method of searching image files based on their formal, including folksonomical clues.
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Full Text Available Sophie Calle's texts are elaborate devices that facilitate the production of figures, of complex symbolic entities. In fact, her work enables us to better understand how figures emerge and unfold in the imaginary. Thus, we find in her Disparitions (Disappearances, a startling figure, which we can name the "Vanished Child". I will present this figure and explain how it stems from the description of a painting by Rembrandt, stolen at the Gardner Museum in Boston. I will start by identifying some of the essential processes implied in the identification of a figure, and, to do so, I will give two short examples, drawn from Witold Gombrowicz and Don DeLillo. Then, after having described in details the figure of the Vanished Child, I will argue, following the French art historian Georges Didi-Huberman in his reading of Walter Benjamin, that figures are auratic objects. Dans ses textes, Sophie Calle emploie des techniques détaillées qui facilitent la production de figures, d'entités symboliques complexes. Son œuvre nous permet effectivement de mieux comprendre comment les figures émergent et se déploient dans l'imaginaire. Ainsi, nous trouvons dans ses Disparitions (Disappearances une figure surprenante que nous pouvons désigner comme « l'enfant disparu ». Je présenterai cette figure en expliquant comment elle découle de la description d'un tableau de Rembrandt volé au musée Gardner à Boston. J'identifierai d'abord quelques-uns des procédés essentiels à l'identification d'une figure, et pour ce faire je donnerai deux exemples, tirés des œuvres de Witold Gombrowicz et Don DeLillo. Puis je décrirai de façon détaillée la figure de l'enfant disparu, avant de démontrer le caractère auratique des figures à partir de la lecture de Walter Benjamin qu'exécute l'historien de l'art français Georges Didi-Huberman.
Liu, Zongyi; Zhou, Hanning
Identifying figure captions has wide applications in producing high quality e-books such as kindle books or ipad books. In this paper, we present a rule-based system to detect horizontal figure captions in old-style documents. Our algorithm consists of three steps: (i) segment images into regions of different types such as text and figures, (ii) search the best caption region candidate based on heuristic rules such as region alignments and distances, and (iii) expand caption regions identified in step (ii) with its neighboring text-regions in order to correct oversegmentation errors. We test our algorithm using 81 images collected from old-style books, with each image containing at least one figure area. We show that the approach is able to correctly detect figure captions from images with different layouts, and we also measure its performances in terms of both precision rate and recall rate.
Two experiments investigated the role of spatial frequency in performance of a figure/ground segregation task based on temporal cues. Figure orientation was much easier to judge when figure and ground portions of the target were defined exclusively by random texture composed entirely of high spatial frequencies. When target components were defined by low spatial frequencies only, the task was nearly impossible except with long temporal delay between figure and ground. These results are inconsistent with the hypothesis that M-cell activity is primarily responsible for figure/ground segregation from temporal delay. Instead, these results point to a distinction between temporal integration and temporal differentiation. Additionally, the present results can be related to recent work on the binding of spatial features over time.
Baylis, G C; Cale, E M
In four experiments, the authors examined the extent to which the ground interpretation of an edge may receive a shape description. These experiments used the priming effect that shapes have on perceptual judgments on a subsequent trial. A robust reduction in error rates and reaction times was seen when the figural shape was the same as that on the previous trial. This repetition priming effect may be due to activation of the shape description of the figure that remained from the previous trial. In contrast, no priming by the shape of the ground was seen even when the contrast sign of the figure reversed between trials. Priming for figural shapes occurred at a relatively abstract level because it was robust across reversals of contrast and orientation. These data suggest that the figural interpretation of a shape receives a shape description but that the ground does not.
Vecera, S P; O'Reilly, R C
An important issue in vision research concerns the order of visual processing. S. P. Vecera and R. C. O'Reilly (1998) presented an interactive, hierarchical model that placed figure-ground segregation prior to object recognition. M. A. Peterson (1999) critiqued this model, arguing that because it used ambiguous stimulus displays, figure-ground processing did not precede object processing. In the current article, the authors respond to Peterson's (1999) interpretation of ambiguity in the model and her interpretation of what it means for figure-ground processing to come before object recognition. The authors argue that complete stimulus ambiguity is not critical to the model and that figure-ground precedes object recognition architecturally in the model. The arguments are supported with additional simulation results and an experiment, demonstrating that top-down inputs can influence figure-ground organization in displays that contain stimulus cues.
Salvagio, Elizabeth; Cacciamani, Laura; Peterson, Mary A
Figure-ground segregation is modeled as inhibitory competition between objects that might be perceived on opposite sides of borders. The winner is the figure; the loser is suppressed, and its location is perceived as shapeless ground. Evidence of ground suppression would support inhibitory competition models and would contribute to explaining why grounds are shapeless near borders shared with figures, yet such evidence is scarce. We manipulated whether competition from potential objects on the ground side of figures was high (i.e., portions of familiar objects were potentially present there) or low (novel objects were potentially present). We predicted that greater competition would produce more ground suppression. The results of two experiments in which suppression was assessed via judgments of the orientation of target bars confirmed this prediction; a third experiment showed that ground suppression is short-lived. Our findings support inhibitory competition models of figure assignment, in particular, and models of visual perception entailing feedback, in general.
Accuracy of detector position toward the kidney location (preciseposition) in renography will resulting the maximum count figure, detectorposition change from the precise point (inaccurate) will decreasing the countrate. Therefore for it had been simulated the influence of count figure ofright kidney (fixed left kidney count) ± 5 % to ± 20 % to relativeuptake figure and individual excretion. Based on the calculation it was foundthat the relation of detector position ± 0.5 cm to ± 2 cm from theprecise point will have effect to relative uptake figure ± (1.25 % to 5.00%), the fixed individual excretion figure. The change is still can beaccepted because the qualitative information with 10 % accuracy is stillacceptable. (author)
Chen, Qiao, E-mail: firstname.lastname@example.org [Department of Maths and Physics, Hunan Institute of Engineering, Xiangtan 411104 (China); Wang, Zhi-yong, E-mail: email@example.com [School of Optoelectronic Information, Chongqing University of Technology, Chongqing 400054 (China); Xie, Zhong-Xiang [Department of Mathematics and Physics, Hunan Institute of Technology, Hengyang 421002 (China)
We investigate the figure of merit of a quantum dot (QD) system irradiated with an external microwave filed by nonequilibrium Green's function (NGF) technique. Results show that the frequency of microwave field influence the figure of merit ZT significantly. At low temperature, a sharp peak can be observed in the figure of merit ZT as the frequency of ac field increases. As the frequency varies, several zero points and resonant peaks emerge in the figure of merit ZT. By adjusting the frequency of the microwave field, we can obtain high ZT. The figure of merit ZT increases with the decreasing of linewidth function Γ. In addition, Wiedemann–Franz law does not hold, particularly in the low frequency region due to multi-photon emission and absorption. Some novel thermoelectric properties are also found in two-level QD system.
Von der Heydt, Rüdiger; Pierson, Rachel
Two phenomena can be observed in the watercolor illusion: illusory color spreading and figure-ground organization. We performed experiments to determine whether the figure-ground effect is a consequence of the color illusion or due to an independent mechanism. Subjects were tested with displays consisting of six adjacent compartments--three that generated the illusion alternating with three that served for comparison. In a first set of experiments, the illusory color was measured by finding the matching physical color in the alternate compartments. Figureness (probability of 'figure' responses, 2AFC) of the watercolor compartments was then determined with and without the matching color in the alternate compartments. The color match reduced figureness, but did not abolish it. There was a range of colors in which the watercolor compartments dominated as figures over the alternate compartments although the latter appeared more saturated in color. In another experiment, the effect of tinting alternate compartments was measured in displays without watercolor illusion. Figureness increased with color contrast, but its value at the equivalent contrast fell short of the figureness value obtained for the watercolor pattern. Thus, in both experiments, figureness produced by the watercolor pattern was stronger than expected from the color effect, suggesting independent mechanisms. Considering the neurophysiology, we propose that the color illusion follows from the principles of representation of surface color in the visual cortex, while the figure-ground effect results from two mechanisms of border ownership assignment, one that is sensitive to asymmetric shape of edge profile, the other to consistency of color borders.
Layton, Oliver W; Mingolla, Ennio; Yazdanbakhsh, Arash
Determining whether a region belongs to the interior or exterior of a shape (figure-ground segregation) is a core competency of the primate brain, yet the underlying mechanisms are not well understood. Many models assume that figure-ground segregation occurs by assembling progressively more complex representations through feedforward connections, with feedback playing only a modulatory role. We present a dynamical model of figure-ground segregation in the primate ventral stream wherein feedback plays a crucial role in disambiguating a figure's interior and exterior. We introduce a processing strategy whereby jitter in RF center locations and variation in RF sizes is exploited to enhance and suppress neural activity inside and outside of figures, respectively. Feedforward projections emanate from units that model cells in V4 known to respond to the curvature of boundary contours (curved contour cells), and feedback projections from units predicted to exist in IT that strategically group neurons with different RF sizes and RF center locations (teardrop cells). Neurons (convex cells) that preferentially respond when centered on a figure dynamically balance feedforward (bottom-up) information and feedback from higher visual areas. The activation is enhanced when an interior portion of a figure is in the RF via feedback from units that detect closure in the boundary contours of a figure. Our model produces maximal activity along the medial axis of well-known figures with and without concavities, and inside algorithmically generated shapes. Our results suggest that the dynamic balancing of feedforward signals with the specific feedback mechanisms proposed by the model is crucial for figure-ground segregation.
Kandil, Farid I; Fahle, Manfred
If the elements within a figure move synchronously while those in the surround move at a different time, the figure is easily segregated from the surround and thus perceived. Lee and Blake (1999) [Visual form created solely from temporal structure. Science, 284, 1165-1168] demonstrated that this figure-ground separation may be based not only on time differences between motion onsets, but also on the differences between reversals of motion direction. However, Farid and Adelson (2001) [Synchrony does not promote grouping in temporally structured displays. Nature Neuroscience, 4, 875-876] argued that figure-ground segregation in the motion-reversal experiment might have been based on a contrast artefact and concluded that (a)synchrony as such was 'not responsible for the perception of form in these or earlier displays'. Here, we present experiments that avoid contrast artefacts but still produce figure-ground segregation based on purely temporal cues. Our results show that subjects can segregate figure from ground even though being unable to use motion reversals as such. Subjects detect the figure when either (i) motion stops (leading to contrast artefacts), or (ii) motion directions differ between figure and ground. Segregation requires minimum delays of about 15 ms. We argue that whatever the underlying cues and mechanisms, a second stage beyond motion detection is required to globally compare the outputs of local motion detectors and to segregate figure from ground. Since analogous changes take place in both figure and ground in rapid succession, this second stage has to detect the asynchrony with high temporal precision.
Layton, Oliver W.; Mingolla, Ennio; Yazdanbakhsh, Arash
Determining whether a region belongs to the interior or exterior of a shape (figure-ground segregation) is a core competency of the primate brain, yet the underlying mechanisms are not well understood. Many models assume that figure-ground segregation occurs by assembling progressively more complex representations through feedforward connections, with feedback playing only a modulatory role. We present a dynamical model of figure-ground segregation in the primate ventral stream wherein feedback plays a crucial role in disambiguating a figure's interior and exterior. We introduce a processing strategy whereby jitter in RF center locations and variation in RF sizes is exploited to enhance and suppress neural activity inside and outside of figures, respectively. Feedforward projections emanate from units that model cells in V4 known to respond to the curvature of boundary contours (curved contour cells), and feedback projections from units predicted to exist in IT that strategically group neurons with different RF sizes and RF center locations (teardrop cells). Neurons (convex cells) that preferentially respond when centered on a figure dynamically balance feedforward (bottom-up) information and feedback from higher visual areas. The activation is enhanced when an interior portion of a figure is in the RF via feedback from units that detect closure in the boundary contours of a figure. Our model produces maximal activity along the medial axis of well-known figures with and without concavities, and inside algorithmically generated shapes. Our results suggest that the dynamic balancing of feedforward signals with the specific feedback mechanisms proposed by the model is crucial for figure-ground segregation. PMID:25346703
Ni Luh Putu Unix Sumartini
Full Text Available The article is aimed to find out the Techniques of Translating English Figurative Expression in ‘Colours’ Magazine by Garuda Indonesia into Indonesian. There are three problems are discussed in this study, namely (1 types of figurative expressions found in the English version of ‘Colours’ magazine and their translation’s equivalence into Indonesian and (2 kinds of translation techniques applied in translating the English figurative expression into Indonesian, This research belongs to qualitative research and the data used in this study were taken from the ‘Colours’ magazine by Garuda Indonesia. The main theory which is applied in this study is taken from the theory of Molina & Albir (2002 in their book entitled Translation Techniques Revisited; A Dynamic and Functionalist Approach. Another theory applied is taken from the theory of McArthur (1992 in his book entitled The Oxford Companion on The English Language. Other supporting theories which are used to support this study are the theory of Larson (1998 in her book entitled Meaning-Based Translation and some other books considered relevant to the topic. The result showed that there are eleven kinds of English figurative expressions found in the data. They are antithesis, euphemism, hyperbole, idioms, irony, metaphor, metonimy, personification, pleonasm, simile and synecdoche. In translating techniques, the translator applied ten translating techniques, they are; adaptation, borrowing, compensation, description, established equivalent, linguistic comprehension, literal technique, modulation, reduction and transposition. In translating a figurative expression from SL into TL, some of the results showed that an English figurative expression is translated into Indonesian figurative translation but some of them can not maintain its figurativeness in Indonesian, therefore the English figurative expression is translated into Indonesian non-figuratively.
Full Text Available According to both experimental research and common sense, classical music is a better fit for figurative art than jazz. We hypothesize that similar fits may reflect underlying crossmodal structural similarities between music and painting genres. We present two preliminary studies aimed at addressing our hypothesis. Experiment 1 tested the goodness of the fit between two music genres (classical and jazz and two painting genres (figurative and abstract. Participants were presented with twenty sets of six paintings (three figurative, three abstract viewed in combination with three sound conditions: 1 silence, 2 classical music, or 3 jazz. While figurative paintings scored higher aesthetic appreciation than abstract ones, a gender effect was also found: the aesthetic appreciation of paintings in male participants was modulated by music genre, whilst music genre did not affect the aesthetic appreciation in female participants. Our results support only in part the notion that classical music enhances the aesthetic appreciation of figurative art. Experiment 2 aimed at testing whether the conceptual categories ‘figurative’ and ‘abstract’ can be extended also to music. In session 1, participants were first asked to classify 30 paintings (10 abstract, 10 figurative, 10 ambiguous that could fit either category as abstract or figurative and then to rate them for pleasantness; in session 2 participants were asked to classify 40 excerpts of music (20 classical, 20 jazz as abstract or figurative and to rate them for pleasantness. Paintings which were clearly abstract or figurative were all classified accordingly, while the majority of ambiguous paintings were classified as abstract. Results also show a gender effect for painting’s pleasantness: female participants rated higher ambiguous and abstract paintings. More interestingly, results show an effect of music genre on classification, showing that it is possible to classify music as figurative or
... we eat. Aspartic acid is also called asparaginic acid. Aspartic acid helps every cell in the body work. It ... release Normal nervous system function Plant sources of aspartic acid include: avocado, asparagus, and molasses. Animal sources of ...
Glutathione metabolism is comparable to a jigsaw puzzle with too many pieces. It is supposed to comprise (i) the reduction of disulfides, hydroperoxides, sulfenic acids, and nitrosothiols, (ii) the detoxification of aldehydes, xenobiotics, and heavy metals, and (iii) the synthesis of eicosanoids, steroids, and iron-sulfur clusters. In addition, glutathione affects oxidative protein folding and redox signaling. Here, I try to provide an overview on the relevance of glutathione-dependent pathways with an emphasis on quantitative data. Recent Advances: Intracellular redox measurements reveal that the cytosol, the nucleus, and mitochondria contain very little glutathione disulfide and that oxidative challenges are rapidly counterbalanced. Genetic approaches suggest that iron metabolism is the centerpiece of the glutathione puzzle in yeast. Furthermore, recent biochemical studies provide novel insights on glutathione transport processes and uncoupling mechanisms. Which parts of the glutathione puzzle are most relevant? Does this explain the high intracellular concentrations of reduced glutathione? How can iron-sulfur cluster biogenesis, oxidative protein folding, or redox signaling occur at high glutathione concentrations? Answers to these questions not only seem to depend on the organism, cell type, and subcellular compartment but also on different ideologies among researchers. A rational approach to compare the relevance of glutathione-dependent pathways is to combine genetic and quantitative kinetic data. However, there are still many missing pieces and too little is known about the compartment-specific repertoire and concentration of numerous metabolites, substrates, enzymes, and transporters as well as rate constants and enzyme kinetic patterns. Gathering this information might require the development of novel tools but is crucial to address potential kinetic competitions and to decipher uncoupling mechanisms to solve the glutathione puzzle. Antioxid. Redox Signal
Zhukhlistova, N. E.; Balaev, V. V.; Lyashenko, A. V.; Lashkov, A. A., E-mail: firstname.lastname@example.org [Russian Academy of Sciences, Shubnikov Institute of Crystallography (Russian Federation)
Endonucleases (EC 3.1) are enzymes of the hydrolase class that catalyze the hydrolytic cleavage of deoxyribonucleic and ribonucleic acids at any region of the polynucleotide chain. Endonucleases are widely used both in biotechnological processes and in veterinary medicine as antiviral agents. Medical applications of endonucleases in human cancer therapy hold promise. The results of X-ray diffraction studies of the spatial organization of endonucleases and their complexes and the mechanism of their action are analyzed and generalized. An analysis of the structural studies of this class of enzymes showed that the specific binding of enzymes to nucleic acids is characterized by interactions with nitrogen bases and the nucleotide backbone, whereas the nonspecific binding of enzymes is generally characterized by interactions only with the nucleic-acid backbone. It should be taken into account that the specificity can be modulated by metal ions and certain low-molecular-weight organic compounds. To test the hypotheses about specific and nonspecific nucleic-acid-binding proteins, it is necessary to perform additional studies of atomic-resolution three-dimensional structures of enzyme-nucleic-acid complexes by methods of structural biology.
Devinck, Frédéric; Spillmann, Lothar
We studied the contribution of multiple cues to figure-ground segregation. Convexity, symmetry, and top-down polarity (henceforth called wide base) were used as cues. Single-cue displays as well as ambiguous stimulus patterns containing two or three cues were presented. Error rate (defined by responses to uncued stimuli) and reaction time were used to quantify the figural strength of a given cue. In the first experiment, observers were asked to report which of two regions, left or right, appeared as foreground figure. Error rate did not benefit from adding additional cues if convexity was present, suggesting that responses were based on convexity as the predominant figural determinant. However, reaction time became shorter with additional cues even if convexity was present. For example, when symmetry and wide base were added, figure-ground segregation was facilitated. In a second experiment, stimulus patterns were exposed for 150ms to rule out eye movements. Results were similar to those found in the first experiment. Both experiments suggest that under the conditions of our experiment figure-ground segregation is perceived more readily, when several cues cooperate in defining the figure. Copyright © 2012 Elsevier Ltd. All rights reserved.
Full Text Available Due to the important role of figures of speech in prose, the present research tried to investigate the figures of speech in the novel, Harry Potter Series, and their Persian translations. The main goal of this research was to investigate the translators’ problems in translating figures of speech from English into Persian. To achieve this goal, the collected data were analyzed and compared with their Persian equivalents. Then, the theories of Newmark (1988 & 2001, Larson (1998, and Nolan (2005 were used in order to find the applied strategies for rendering the figures of speech by the translators. After identifying the applied translation strategies, the descriptive and inferential analyses were applied to answer the research question and test its related hypothesis. The results confirmed that the most common pitfalls in translating figures of speech from English into Persian based on Nolan (2005 were, not identifying of figures of speech, their related meanings and translating them literally. Overall, the research findings rejected the null hypothesis. The findings of present research can be useful for translators, especially beginners. They can be aware of the existing problems in translating figures of speech, so they can avoid committing the same mistakes in their works.
Burda, Brittany U; O'Connor, Elizabeth A; Webber, Elizabeth M; Redmond, Nadia; Perdue, Leslie A
Systematic reviewers often encounter incomplete or missing data, and the information desired may be difficult to obtain from a study author. Thus, systematic reviewers may have to resort to estimating data from figures with little or no raw data in a study's corresponding text or tables. We discuss a case study in which participants used a publically available Web-based program, called webplotdigitizer, to estimate data from 2 figures. We evaluated and used the intraclass coefficient and the accuracy of the estimates to the true data to inform considerations when using estimated data from figures in systematic reviews. The estimates for both figures were consistent, although the distribution of estimates in the figure of a continuous outcome was slightly higher. For the continuous outcome, the percent difference ranged from 0.23% to 30.35% while the percent difference of the event rate ranged from 0.22% to 8.92%. For both figures, the intraclass coefficient was excellent (>0.95). Systematic reviewers should consider and be transparent when estimating data from figures when the information cannot be obtained from study authors and perform sensitivity analyses of pooled results to reduce bias. Copyright © 2017 John Wiley & Sons, Ltd.
Kim, Sung-Ho; Feldman, Jacob
Figure/ground interpretation is a dynamic and complex process involving the cooperation and competition of a number of perceptual factors. Most research has assumed that figure/ground assignment is globally consistent along the entire contour of a single figure, meaning that the one side of each boundary is interpreted as figure along the entire length of the boundary, and the other side interpreted as ground. We investigated a situation that challenges this assumption, because local cues to figure/ground conflict with global cues: a "negative part," a contour region that appears locally convex but that the global form requires be concave. To measure figure/ground assignment, we use a new task based on local contour motion attribution that allows us to measure border ownership locally at points along the contour. The results from two experiments showed that the more salient a negative part is, the more border ownership tended to locally reverse within it, creating an inconsistency in figure/ground assignments along the contour. This suggests that border ownership assignment is not an all-or-none process, but rather a locally autonomous process that is not strictly constrained by global cues.
Oliver W. Layton
Full Text Available Determining whether a region belongs to the interior or exterior of a shape (figure-ground segregation is a core competency of the primate brain, yet the underlying mechanisms are not well understood. Many models assume that figure-ground segregation occurs by assembling progressively more complex representations through feedforward connections, with feedback playing only a modulatory role. We present a dynamical model of figure-ground segregation in the primate ventral stream wherein feedback plays a crucial role in disambiguating a figure’s interior and exterior. We introduce a processing strategy whereby jitter in RF center locations and variation in RF sizes is exploited to enhance and suppress neural activity inside and outside of figures, respectively. Feedforward projections emanate from units that model cells in V4 known to respond to the curvature of boundary contours (curved contour cells, and feedback projections from units predicted to exist in IT that strategically group neurons with different RF sizes and RF center locations (teardrop cells. Neurons (convex cells that preferentially respond when centered on a figure dynamically balance feedforward (bottom-up information and feedback from higher visual areas. The activation is enhanced when an interior portion of a figure is in the RF via feedback from units that detect closure in the boundary contours of a figure. Our model produces maximal activity along the medial axis of well-known figures with and without concavities, and inside algorithmically generated shapes. Our results suggest that the dynamic balancing of feedforward signals with the specific feedback mechanisms proposed by the model is crucial for figure-ground segregation.
Pitts, Michael A; Martínez, Antígona; Brewer, James B; Hillyard, Steven A
The temporal sequence of neural processes supporting figure-ground perception was investigated by recording ERPs associated with subjects' perceptions of the face-vase figure. In Experiment 1, subjects continuously reported whether they perceived the face or the vase as the foreground figure by pressing one of two buttons. Each button press triggered a probe flash to the face region, the vase region, or the borders between the two. The N170/vertex positive potential (VPP) component of the ERP elicited by probes to the face region was larger when subjects perceived the faces as figure. Preceding the N170/VPP, two additional components were identified. First, when the borders were probed, ERPs differed in amplitude as early as 110 msec after probe onset depending on subjects' figure-ground perceptions. Second, when the face or vase regions were probed, ERPs were more positive (at ∼ 150-200 msec) when that region was perceived as figure versus background. These components likely reflect an early "border ownership" stage, and a subsequent "figure-ground segregation" stage of processing. To explore the influence of attention on these stages of processing, two additional experiments were conducted. In Experiment 2, subjects selectively attended to the face or vase region, and the same early ERP components were again produced. In Experiment 3, subjects performed an identical selective attention task, but on a display lacking distinctive figure-ground borders, and neither of the early components were produced. Results from these experiments suggest sequential stages of processing underlying figure-ground perception, each which are subject to modifications by selective attention.
Aptekar, Jacob W; Keleş, Mehmet F; Lu, Patrick M; Zolotova, Nadezhda M; Frye, Mark A
Many animals rely on visual figure-ground discrimination to aid in navigation, and to draw attention to salient features like conspecifics or predators. Even figures that are similar in pattern and luminance to the visual surroundings can be distinguished by the optical disparity generated by their relative motion against the ground, and yet the neural mechanisms underlying these visual discriminations are not well understood. We show in flies that a diverse array of figure-ground stimuli containing a motion-defined edge elicit statistically similar behavioral responses to one another, and statistically distinct behavioral responses from ground motion alone. From studies in larger flies and other insect species, we hypothesized that the circuitry of the lobula--one of the four, primary neuropiles of the fly optic lobe--performs this visual discrimination. Using calcium imaging of input dendrites, we then show that information encoded in cells projecting from the lobula to discrete optic glomeruli in the central brain group these sets of figure-ground stimuli in a homologous manner to the behavior; "figure-like" stimuli are coded similar to one another and "ground-like" stimuli are encoded differently. One cell class responds to the leading edge of a figure and is suppressed by ground motion. Two other classes cluster any figure-like stimuli, including a figure moving opposite the ground, distinctly from ground alone. This evidence demonstrates that lobula outputs provide a diverse basis set encoding visual features necessary for figure detection. Copyright © 2015 the authors 0270-6474/15/357587-13$15.00/0.
. The expected number of cancer cases in children aged between 0 and 14 years of age is approximately 7,000 in the period 2016- 2020, while the corresponding figure for adolescents between 15 and 19 years of age is 4,000, with no relevant variation in comparison with the previous five-year period. The present findings update descriptive cancer epidemiology in children and adolescents in Italy based on data provided by an extensive network of general and specialized population-based cancer registries. Data obtained from cancer registries are supplemented by additional information collected by specialized clinical AIEOP centres and mortality reports collected by the National Institute of Statistics (ISTAT). Incidence rates reported in Italy were slightly higher in comparison to other developed Countries, but relatively consistent between different Italian areas. Our results also showed that the significant increase in cancer incidence observed until the end of Nineties has halted, with the exception solely of thyroid cancer in adolescents. Efficacy of therapeutic protocols has improved constantly since the Seventies, and recent findings confirm this trend in all age groups and, in particular, for rarer tumours and cancer types that have very poor prognosis. Findings derived from cross-analysis with AIEOP data suggest that it is possible to further improve the efficiency of our healthcare system, in particular for adolescents; migration can be reduced with a more rational use of hospitals throughout Italy.
Full Text Available This research intended to create preferences on geometric figures using a classical conditioning procedurewhere 2 specific variations of musical structure were used -mayor and dissonant tones- as unconditionedstimulus. 24 university students with an age average of 23 years were exposed to stimular conditionswhere 2 geometric figures (CS+, were matched with mayor tones (UCS+ and other 2 (CS- withdissonant (UCS-; subsequently the figures were rated on a scale (where +10 = very pleasant and -10 =very unpleasant. According with the formulated hypothesis and the previous discoveries in both basicand applied research, three of the four conditions tested showed significant values using the Wilcoxonsign ranks test.
Lychagina, T. A.; Nikolaev, D. I.
The errors in measuring the crystallographic texture described by pole figures are studied. A set of diffraction spectra for a sample of the MA2-1 alloy (Mg + 4.5% Al + 1% Zn) are measured, simulation of individual spectra on the basis of which the pole figures were obtained is performed, and their errors are determined. The conclusion about the possibility of determining the effect of errors of the diffraction peak half-width on the pole figure errors that was drawn in our previous studies is confirmed
Keisalo, Marianna Päivikki
This article develops an analytic approach to comedic performance by examining the performance of the Chapayeka ritual clowns as a series of semiotic shifts and reversals: the Chapayekas play with images and contexts, introducing unpredictable figures to effectively shift the grounding conditions...... to function as both symbolic figures in the ritual and self-contained contextual grounds, which enables them to produce further signs and manipulate figure-ground relations within and beyond the ritual. The analytic view developed here is informed by the complex and multilayered semiotics of comedic...
Radilová, J; Radil-Weiss, T
A permanently illuminated pattern of Mach's truncated pyramid can be perceived according to the experimental instruction given, either as a three-dimensional reversible figure with spontaneously changing convex and concave interpretation (in one experiment), or as a two-dimensional reversible figure-ground pattern (in another experiment). The reversal rate was about twice as slow, without the subjects being aware of it, if it was perceived as a three-dimensional figure compared to the situation when it was perceived as two-dimensional. It may be hypothetized that in the three-dimensional case, the process of perception requires more sequential steps than in the two-dimensional one.
Qiu, Fangtu T.; von der Heydt, Rüdiger
Figure-ground organization is a process by which the visual system identifies some image regions as foreground and others as background, inferring three-dimensional (3D) layout from 2D displays. A recent study reported that edge responses of neurons in area V2 are selective for side-of-figure, suggesting that figure-ground organization is encoded in the contour signals (border-ownership coding). Here we show that area V2 combines two strategies of computation, one that exploits binocular ster...
Figurative language is a part of semantic. This research analyzed the figurative language used in the lyric of firework by Katy Perry. The aims of this research are to find out the figurative languages used in the lyric of firework and to analyze the contextual meaning of figurative language used in that song. It is expected the result of this study will be useful for the reader especially in knowing what figurative language is and what kinds of figurative language are. The design of this res...
Ottmann, Karl; Tronnier, Michael; Mitteldorf, Christina
The mitotic rate is an important prognostic criterion in patients with thin melanoma ≤ 1 mm. The aim of this study was to investigate the reproducibility of the mitotic rate in thin melanoma in hematoxylin-eosin (H&E) stain and compare it with the detection of mitotic figures by immunohistochemistry. The number of mitoses stated in the routine diagnostic report in 190 pT1 melanomas was compared with the number gained from re-evaluation of H&E sections and the number detected after staining with the mitotic marker, phosphohistone H3 (PHH3). Two different approaches were used for choosing the "hot spot" for evaluation (dermal vs epidermal/dermal). Comparing routine H&E-stained slides with re-evaluation slides, the number of mitotic figures was slightly variable. However, findings did not result in a change of the tumor stage. In 34% of the tumors with dermal mitotic figures on H&E, mitoses could not be found in the corresponding PHH3 slide anymore. In 4% of the cases, stage relevant mitoses could only be found by PHH3 immunohistochemistry. This is a single center study. Immunohistochemical staining for mitotic figures does not replace a careful evaluation of H&E-stained slides. Immunohistochemical detection of mitosis is only an additional tool; the time-saving effect is therefore negligible. Copyright © 2015 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.
Full Text Available A partir du traitement des figures dans le Traité de l’Argumentation (TA de Perelman et Olbrechts-Tyteca, cet article porte sur la question de la place des figures dans la théorie de l’argumentation. La première partie revient brièvement sur différentes formes de rhétorique, dont une rhétorique de l’ornement ayant pour instrument principal les figures. Une théorie moderne de l’argumentation orientée vers la recherche des fallacies établit une coupure radicale entre argumentation, instrument de recherche de la vérité et rhétorique ornée, que Locke caractérise comme « a powerful instrument of error and deceit ». Cette conception suppose l’usage d’un langage qu’on peut rapidement caractériser comme « artificiel », qui n’est pas celui de l’argumentation ordinaire. Avant d’être des « decorations » les figures sont des « instruments » de structuration de la parole ; et les topoi, instruments de l’argumentation, n’obéissent pas à d’autres mécanismes que les tropes, qui semblent toujours parler à côté et manquer leur objet. La seconde partie s’intéresse à une partie quelque peu délaissée du TA, l’usage qu’il fait des figures et la vision théorique, à la fois cavalière et décisive, qu’il en propose. Le TA ouvre la voie à une conception des figures non pas comme « vain ornement » mais comme une première sémantique du discours argumentatif ; c’est ce qu’on peut montrer sur le cas des « figures du choix, de la présence et de la communion ». En conséquence, la pensée des figures peut et doit être intégrée à une théorie de l’argumentation qui prend en compte le langage dans la parole, avec ses stratégies de construction des objets, du locuteur, de l’interlocuteur et de leurs émotions.This paper deals with the treatment of figures of speech in Perelman’s and Olbrechts-Tyteca’s Treatise on Argumentation (TA, and, more broadly, with the place of
Full Text Available Large variability in tests and differences in scoring systems used to study central coherence in eating disorders may lead to different interpretations, inconsistent findings and between study discrepancies. This study aimed to address inconsistencies by collating data from several studies from the same research group that used the Rey Osterrieth Complex Figure Test (Rey Figure in order to produce norms to provide benchmark data for future studies.Data was collated from 984 participants in total. Anorexia Nervosa, Bulimia Nervosa, recovered Anorexia Nervosa, unaffected family members and healthy controls were compared using the Rey Figure.Poor global processing was observed across all current eating disorder sub-groups and in unaffected relatives. There was no difference in performance between recovered AN and HC groups.This is the largest dataset reported in the literature and supports previous studies implicating poor global processing across eating disorders using the Rey Figure. It provides robust normative data useful for future studies.
Hulbert, S.L.; Sharma, S.
At present, grazing incidence mirrors are used almost exclusively as the first optical element in VUV and soft x-ray synchrotron radiation beamlines. The performance of these mirrors is determined by thermal and mechanical stress-induced figure errors as well as by figure errors remaining from the grinding and polishing process. With the advent of VUV and soft x-ray undulators and wigglers has come a new set of thermal stress problems related to both the magnitude and the spatial distribution of power from these devices. In many cases the power load on the entrance slits and gratings in these beamlines is no longer negligible. The dependence of thermally-induced front-end mirror figure errors on various storage ring and insertion device parameters (especially those at the National Synchrotron Light Source) and the effects of these figure errors on two classes of soft x-ray beamlines are presented.
Ramsey, Brian D.; Kilaru, Kiranmayee; Atkins, Carolyn; Gubarev, Mikhail V.; Broadway, David M.
Differential deposition corrects the low- and mid- spatial-frequency deviations in the axial figure of Wolter-type grazing incidence X-ray optics. Figure deviations is one of the major contributors to the achievable angular resolution. Minimizing figure errors can significantly improve the imaging quality of X-ray optics. Material of varying thickness is selectively deposited, using DC magnetron sputtering, along the length of optic to minimize figure deviations. Custom vacuum chambers are built that can incorporate full-shell and segmented Xray optics. Metrology data of preliminary corrections on a single meridian of full-shell x-ray optics show an improvement of mid-spatial frequencies from 6.7 to 1.8 arc secs HPD. Efforts are in progress to correct a full-shell and segmented optics and to verify angular-resolution improvement with X-ray testing.
Mass médias et figures du religieux islamique au Mali: entre négociation et appropriation de l'espace public. ... (development of means of transportation and communications technologies) and the extension of democratic rights and freedoms.
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This unique book covers the fundamental principle of electron diffraction, basic instrumentation of RHEED, definitions of textures in thin films and nanostructures, mechanisms and control of texture formation, and examples of RHEED transmission mode measurements of texture and texture evolution of thin films and nanostructures. Also presented is a new application of RHEED in the transmission mode called RHEED pole figure technique that can be used to monitor the texture evolution in thin film growth and nanostructures and is not limited to single crystal epitaxial film growth. Details of the construction of RHEED pole figures and the interpretation of observed pole figures are presented. Materials covered include metals, semiconductors, and thin insulators. This book also: Presents a new application of RHEED in the transmission mode Introduces a variety of textures from metals, semiconductors, compound semiconductors, and their characteristics in RHEED pole figures Provides examples of RHEED measurements o...
U.S. Environmental Protection Agency — Each year EPA produces a report called Advancing Sustainable Materials Management: Facts and Figures. It includes information on municipal solid waste (MSW)...
U.S. Environmental Protection Agency — The files in the dataset are labeled according to table or figure number as listed in the paper (Gavett et al., Particle and Fibre Toxicology, 13:17, 2016). The...
Energy in Sweden: Facts and figures 2010 contains the tabular for most of the diagrams in the main publication (STEM-ET--2010-47). These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. Facts and figures is also available at www.energimyndigheten.se in pdf and excel file formats. Energy statistics is published on short term basis and yearly basis. For the year 2009 only short term statistics is available. In Energy in Sweden 2010 yearly statistics is presented up to and including 2008. For 2009 short term statistics is used. Breakdowns into certain types of energy carriers vary somewhat depending on whether short term or yearly statistics is used. Please note that the figures have been rounded up or down, therefore totals do not always comply with the sum of individual figures
In two experiments, the effect of category salience on retrieval experience was investigated. In Experiment 1, participants rated typicality or concreteness of personality traits that differed in stereotype reference (i.e., consistent, inconsistent, and neutral in relation to the age stereotype). More remember judgments were given for consistent and inconsistent traits in contrast to neutral traits, thereby indicating a figure/ground asymmetry. In Experiment 2, neutral traits were excluded and a classical figure/ground phenomenon was demonstrated for the retrieval experience of traits (i.e., reversibility of an ambiguous figure after typicality and untypicality ratings). Altogether, the results suggest that metacognitive trait representations depend on principles of figure/ground asymmetries rather than on functional principles of social information processing.
Vecera, S P; O'Reilly, R C
Traditional bottom-up models of visual processing assume that figure-ground organization precedes object recognition. This assumption seems logically necessary: How can object recognition occur before a region is labeled as figure? However, some behavioral studies find that familiar regions are more likely to be labeled figure than less familiar regions, a problematic finding for bottom-up models. An interactive account is proposed in which figure-ground processes receive top-down input from object representations in a hierarchical system. A graded, interactive computational model is presented that accounts for behavioral results in which familiarity effects are found. The interactive model offers an alternative conception of visual processing to bottom-up models.
Malaspina, Dolores; Simon, Naomi; Goetz, Raymond R; Corcoran, Cheryl; Coleman, Eliza; Printz, David; Mujica-Parodi, Lilianne; Wolitzky, Rachel
Schizophrenia subjects are impaired in a number of visual attention paradigms. However, their performance on tests of figure-ground visual perception (FGP), which requires subjects to visually discriminate figures embedded in a rival background, is relatively unstudied. We examined FGP in 63 schizophrenia patients and 27 control subjects and found that the patients performed the FGP test reliably and had significantly lower FGP scores than the control subjects. Figure-ground visual perception was significantly correlated with other neuropsychological test scores and was inversely related to negative symptoms. It was unrelated to antipsychotic medication treatment. Figure-ground visual perception depends on "top down" processing of visual stimuli, and thus this data suggests that dysfunction in the higher-level pathways that modulate visual perceptual processes may also be related to a core defect in schizophrenia.
Energy in Sweden: Facts and figures 2010 contains the tabular for most of the diagrams in the main publication (STEM-ET--2010-47). These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. Facts and figures is also available at www.energimyndigheten.se in pdf and excel file formats. Energy statistics is published on short term basis and yearly basis. For the year 2009 only short term statistics is available. In Energy in Sweden 2010 yearly statistics is presented up to and including 2008. For 2009 short term statistics is used. Breakdowns into certain types of energy carriers vary somewhat depending on whether short term or yearly statistics is used. Please note that the figures have been rounded up or down, therefore totals do not always comply with the sum of individual figures