Enzīmu inducētas rezistences noteikšana klīniski nozīmīgos Gram negatīvo baktēriju celmos

OpenAIRE

Vēvere, Indra

2013-01-01

Noteikta K.pneumoniae, P.aeruginosa, A.baumannii un E.coli rezistence pret antibakteriālajiem preparātiem. Darbs izstrādāts RAKUS Tuberkulozes un plaušu slimību centra Mikobakterioloģijas laboratorijā. Izanalizēti materiāli no 2012. gada. No elpceļu izolātiem iegūtas tīrkultūras, kuru rezistences spēja pārbaudīta ar β-laktāmu, aminoglikozīdu un hinolonu klases antibakteriālajiem preparātiem. Izmantotās metodes-disku difūzijas tests, Hodge tests, E-tests un dubultdisku metode. Izdalīti 267...

Antibiotic rezistance genes in soil actinobacteria

OpenAIRE

Patrmanová, Tereza

2016-01-01

Actinobacteria are important members of the soil ecosystems, where they are involved in organic matter decomposition. It is worth mentioning that their secondary metabolism allows them to produce a variety of different compounds. These compounds include antibiotics, among them aminoglycosides have a place in clinical practice. These antibiotics are significant due to a broad spectrum of activities against both gram-negative and gram-positive bacteria. However, their use currently carries a ri...

Antibiotiku aprite Benu aptiekā 7

OpenAIRE

Mičule, Baiba

2013-01-01

Antibiotikas plaši pielieto infekciju slimību ārstēšanā. Bieži vien ārsti antibiotikas izraksta arī vīrusa infekcijas gadījumā, tādēļ pieaug antibiotiku patēriņš un aizvien vairāk tiek runāts par antibiotiku rezistences veidošanos, kā rezultātā baktērijas kļūst nejūtīgas pret antibakteriālajiem līdzekļiem. Bakalaura darba mērķis bija izpētīt perorāli lietojamo antibiotiku apriti BENU aptiekā 7, laika posmā no 2011. gada 1. janvāra līdz 2012. gada 31. decembrim. Veicot pētījumu, tika no...

Tělesná výška a inzulinová rezistence

Czech Academy of Sciences Publication Activity Database

Málková, J.; Kraml, P.; Valenta, Zdeněk

2005-01-01

Roč. 47, 4 suppl. (2005), s. 65 ISSN 0010-8650. [Výroční sjezd České kardiologické společnosti /13./. 08.05.2005-11.05.2005, Brno] Institutional research plan: CEZ:AV0Z10300504 Keywords : cardiovascular risk * body height * insulin resistance Subject RIV: BB - Applied Statistics, Operational Research

Teror, selhání, odboj. Konfliktní paměť ozbrojených aktů protikomunistické rezistence

Czech Academy of Sciences Publication Activity Database

Devátá, Markéta

2015-01-01

Roč. 22, 3/4 (2015), s. 398-439 ISSN 1210-7050 R&D Projects: GA MK(CZ) DF11P01OVV034 Keywords : communist régime * civilian resistance * national memory Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

Antibiotic Susceptibility Profiles of Listeria monocytogenes Strains Isolated from Food Products and Clinical Samples

Directory of Open Access Journals (Sweden)

Caplan Marius Eduard

2014-06-01

Full Text Available Listeria monocytogenes are o distribuţie ubiquitară în natură şi poate contamina produsele alimentare de origine animală, provocând infecţii severe la om. Până în prezent există foarte puține date cu privire la profilurile de rezistenţă ale tulpinilor circulante în România. Scopul acestui studiu a fost determinarea pattern-urilor de rezistenţă la antibiotice ale unor tulpini de L. monocytogenes (n=37 izolate din produse alimentare de origine animală şi din probe clinice. Probele din alimente (carne şi produse lactate, au fost colectate în perioada 2009-2013. Probele clinice au fost recoltate de la pacienţi cu septicemie, meningită/meningo-encefalită, cazuri de avort spontan şi nou-născuţi, spitalizaţi în perioada Aprilie 2010 - Aprilie 2013 în trei Instituţii Medicale din Bucureşti: Spitalul Elias, Spitalul Victor Babes si Institutul Naţional de Boli Infecţioase (INBI Matei Bals. Toate tulpinile testate au prezentat rezistenţă la cefalosporine şi acidul nalidixic; o tulpină izolată din melci fierţi a fost rezistentă la Trimetoprim/sulfametoxazol. Rezistenţa unora dintre tulpinile analizate la ampicilina, antibiotic de elecţie pentru terapia infecţiilor cauzate de L. monocytogenes, subliniază necesitatea testării in vitro a sensibilitatii la antibiotice a fiecarui izolat clinic pentru a stabili eficienţa diferitelor antibiotice, precum şi a unor studii epidemiologice extinse în scopul stabilirii profilurilor de rezistenţă ale tulpinilor de L. monocytogenes circulante în ţara noastră.

Tailings dams stability analysis using numerical modelling of geotechnical and geophysical data

Science.gov (United States)

Mihai, S.; Zlagnean, M.; Oancea, I.; Petrescu, A.

2009-04-01

Methods for monitoring seepage and detecting internal erosion are essential for the safety evaluation of embankment dams. Internal erosion is one of the major reasons for embankment dam failures, and there are thousands of large tailings dams and waste-rock dumps in the world that may pe considered as hotspots for environmental impact. In this research the geophysical survey works were performed on Cetatuia 2 tailings dam. Electrical resistivity imaging (ERI) method was able to detect spatially anomalous zones inside the embankment dam. These anomalies are the results of internal erosion phenomena which may progressing inside the dam and is difficult to detect by conventional methods. Data aquired by geophysical survey together with their interpretations were used in the numerical model for slope stability assessment. The final results show us the structural weakness induced by the presence of internal erosion elements especially for seismic loading case. This research methodology may be also available for tailings dam monitoring purposes. Electrical Rezistivity Imaging (ERI) was performed on Cetatuia 2 dam at the Uranium Milling Plant Feldioara, in order to map areas with lateral and vertical changes in resistivity. The electrodes are connected to an automated computer operated switch box that selects the 4 electrodes to be used. A computer controls the switch box and the measuring device, and runs a program that selects the electrodes, makes the measurement, and stores the measurement. For inversion processing procedures was used Res2Din software. The measured resistivity were plotted by the pseudo section contouring method. There are five resistivity pseudosections obtained from the Cetatuia 2 tailings dam during the october 2007 measurements. Four transversal profiles trans1 to trans4 are perpendicular to the berms and the longitudinal one long1 is placed along dam's crest. The high resistivities near the berms surfaces corresponds to unsaturated fill materials

Insulīna rezistence PCOS pacientēm un tās saistība ar citiem riska faktoriem (kardiovaskulāro slimību, cukura diabēts)

OpenAIRE

Gutņikovs, Oļegs

2014-01-01

Darba pamatojums: PCOS ir viena no biežākajām endokrinopātijām sievietēm reproduktīvajā vecumā. Pēc literatūras datiem, pacientēm ar PCOS pieaug KVS un cukura diabēta attīstības risks. Tāpēc šajā pētījumā tiek analizēts, vai šie dati attiecināmi arī uz Latvijas populāciju. Pētījuma mērķis: salīdzināt KVS attīstības risku PCOS pacientēm ar vispārējo populāciju Latvijas teritorijā. Materiāli un metodes: Retrospektīva pētījuma ietvaros tika analizētas slimības vēstures PCOS pacientēm (E28...

Inzulínová rezistence a postprandiální stav u diabetu 2. typu. Vliv frekvence a složení jídel na metabolismus glukózy a další projevy metabolického syndromu

OpenAIRE

Thieme, Lenka

2017-01-01

The project focuses on dietary interventions in type 2 diabetes(T2D). The aim was to investigate how glucose metabolism and other manifestations of insulin resistance should be influenced by a) the composition of macronutrients and b) frequency of meals; and to characterize the possible mechanisms of these dietary interventions in patients with T2D. A. In a randomized crossover study, 50 patients T2D and 50 age-matched healthy subjects underwent in a random order meal tolerance tests with thr...