WorldWideScience

Sample records for revolutsioon mida ei

  1. Maa, mis on ja mida ei ole / Õnne Kepp

    Index Scriptorium Estoniae

    Kepp, Õnne

    2006-01-01

    Gustav Suitsu 1913. aastal ilmunud luulekogust "Tuulemaa". Tuulemaa kujundit kasutatakse Eestimaa sünonüümina, ühtaegu nii reaalse maana kui ka irreaalse paigana, mida ei eksisteeri, mida pole olemas

  2. MIDAS

    International Nuclear Information System (INIS)

    Sjo, T.; Andersson, E.B.; Kornfeldt, H.

    1988-01-01

    The increasing importance of advanced and reliable in-service inspection of major reactor components has led to the development of a new tool for underwater inspections - MIDAS. This is a remotely operated vehicle carrying a TV camera and an eddy current probe, thus giving the inspector the freedom to easily maneuver into selected inspection areas. The combination of visual inspection with the possibility of EC evaluation of indications gives a high degree of confidence in the overall inspection results

  3. Kas nad tõesti ei tea, mida räägivad? / Jüri Ginter

    Index Scriptorium Estoniae

    Ginter, Jüri, 1954-

    2009-01-01

    2009. a. sügisest kehtima hakkava põhikooli- ja gümnaasiumiseaduse § 28 sätestab, et vastuvõtt gümnaasiumi toimub põhikooli lõpetamise tulemuste alusel. Samas seaduses ei ole öeldud, et lähtuma peab keskmisest hindest, aastahinnetest vms

  4. Kohtunik, ma ei saa teist aru! / Marko Mägi

    Index Scriptorium Estoniae

    Mägi, Marko

    2007-01-01

    Kohtuasjast USAs Arizonas kolme inimsmugeldamises kahtlustatava Mehhiko mehe üle, kelle suhtes ei saa kohtuotsust langetada, kuna ei suudeta tuvastada keelt, mida kohtualused on võimelised mõistma süüdistusest aru saamiseks

  5. MIDAS documentation

    International Nuclear Information System (INIS)

    Seeman, S.E.

    1981-09-01

    MIDAS, the Master Information and Data Acquisition System, is a computerized system being implemented on FFTF to control the work released to the plant. The purpose of this system is to demonstrate the safety enhancement provided for LMFBRs when the operator has instant recall to the status of all work released to the plant, the interrelationships between functional equipment groups in the plant, and the relationships of equipment to safety functions

  6. Telli seda - ei tea mida / Ike Volkov

    Index Scriptorium Estoniae

    Volkov, Ike, 1951-

    2011-01-01

    Olukorrast Tallinna linnaplaneerimises ja linnaehituses. Ametnike vastutusest, ametiasutuste kompetentsusest, töö efektiivsusest, kehtivate seadustega ja ettekirjutustega arvestamisest, probleemidest hangetega

  7. Mida tegi Moskva linnavalitsuse lennuk Tallinnas? / Lauri Birkan

    Index Scriptorium Estoniae

    Birkan, Lauri

    2009-01-01

    9. oktoobril 2009 maandus Tallinna lennuväljale lennuk registriga VQ-BBS, küljel kiri Airline of the Moscow Government. Vastust küsimusele, mida tegi Moskva linnavalitsuse lennuk Tallinnas, ei saanud autor ei Tallinna lennujaamast, linnavalitsusest ega ka välisministeeriumist

  8. Документальная драма о российской оппозиции / Эвелин Калдоя

    Index Scriptorium Estoniae

    Калдоя, Эвелин, 1980-

    2009-01-01

    Tallinna kinos Sõprus esilinastus dokumentaalfilm opositsionääridest Venemaal "Revolutsioon, mida ei tulnud" (režissöör Aljona Polunina, tootjad Kuukulgur Film ja Matila Röhr Productions Soomest)

  9. Uinutav dokumentaaldraama Vene äärmusopositsionääridest / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2009-01-01

    7. jaanuaril esilinastub Tallinna kinos Sõprus dokumentaalfilm opositsionääridest Venemaal "Revolutsioon, mida ei tulnud" (režissöör Aljona Polunina, produtsent Jaak Kilmi; tootjad Kuukulgur Film ja Matila Röhr Productions Soomest, 2008)

  10. Antiputinlaste hingeelu / Olev Remsu

    Index Scriptorium Estoniae

    Remsu, Olev, 1947-

    2009-01-01

    Dokumentaalfilmist "Revolutsioon, mida ei tulnud", režissöör Aljona Polunina, produtsendid Jaak Kilmi ja Ilkka Matila, Kuukulgur Film ja Matila Röhr productions, 2008. Esilinastus Eestis kinos Sõprus 7. jaan. 2009

  11. Kino nagu elu, mis on hullemgi veel / Mart Laar

    Index Scriptorium Estoniae

    Laar, Mart, 1960-

    2009-01-01

    Dokumentaalfilmist "Revolutsioon, mida ei tulnud", režissöör Aljona Polunina, produtsendid Jaak Kilmi ja Ilkka Matila, Kuukulgur Film ja Matila Röhr productions, 2008. Esilinastus Eestis kinos Sõprus 7. jaan. 2009

  12. PyMidas: Interface from Python to Midas

    Science.gov (United States)

    Maisala, Sami; Oittinen, Tero

    2014-01-01

    PyMidas is an interface between Python and MIDAS, the major ESO legacy general purpose data processing system. PyMidas allows a user to exploit both the rich legacy of MIDAS software and the power of Python scripting in a unified interactive environment. PyMidas also allows the usage of other Python-based astronomical analysis systems such as PyRAF.

  13. Piinamise välistanud Rice ei täpsustanud, mis piinamine on / Ahto Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Ahto, 1970-

    2005-01-01

    USA välisminister Condoleezza Rice ütles Brüsselis, et USA võimud ei rakenda vangide piinamist ei kodu- ega välismaal. Samas ei selgitanud ta, mida USA loeb piinamiseks. NATO peasekretäri Jaap de Hoop Schefferi kommentaare

  14. Midas heeft gelijk.

    NARCIS (Netherlands)

    dr. Lars B. Borghouts

    2006-01-01

    Het boek "Lichamelijke Oefening" van Midas Dekkers heeft heel wat stof doen opwaaien de afgelopen maanden. Dit artikel is een uitgebreide analyse van het boek, en of de ophef die het heeft veroorzaakt terecht is.

  15. MiDAS

    DEFF Research Database (Denmark)

    McIlroy, Simon Jon; Saunders, Aaron Marc; Albertsen, Mads

    2015-01-01

    The Microbial Database for Activated Sludge (MiDAS) field guide is a freely available online resource linking the identity of abundant and process critical microorganisms in activated sludge wastewater treatment systems to available data related to their functional importance. Phenotypic properties...... of some of these genera are described, but most are known only from sequence data. The MiDAS taxonomy is a manual curation of the SILVA taxonomy that proposes a name for all genus-level taxa observed to be abundant by large-scale 16 S rRNA gene amplicon sequencing of full-scale activated sludge...... communities. The taxonomy can be used to classify unknown sequences, and the online MiDAS field guide links the identity to the available information about their morphology, diversity, physiology and distribution. The use of a common taxonomy across the field will provide a solid foundation for the study...

  16. MIDAS Website. Revised

    Science.gov (United States)

    Goodman, Allen; Shively, R. Joy (Technical Monitor)

    1997-01-01

    MIDAS, Man-machine Integration Design and Analysis System, is a unique combination of software tools aimed at reducing design cycle time, supporting quantitative predictions of human-system effectiveness and improving the design of crew stations and their associated operating procedures. This project is supported jointly by the US Army and NASA.

  17. Titles of Midas

    Directory of Open Access Journals (Sweden)

    G. L. Huxley

    2001-09-01

    Full Text Available The Phrygian inscription on the tomb at Yazılıkaya (8th century gives Midas the titles wanax and lawagtas, paralled in Mycenaean, and there were strong connections between his dynasty and Greek Aeolis.

  18. Mida tegi peaminister Ansip 20 aastat tagasi? / Tarmo Vahter

    Index Scriptorium Estoniae

    Vahter, Tarmo, 1970-

    2007-01-01

    Endine Tartu KEK-i juhataja Jaak Kalm ja Tartu linna täitevkomitee aseesimees Robert Närska 1988. a. 2. veebruari meeleavaldusest ja selle laialiajamisest Tartus. Andrus Ansipi väidetavast kommentaarist meeleavalduse laialiajamisel. Peaminister Andrus Ansipi vastuseid küsimustele, miks EKP Tartu rajoonikomitee ei valinud teda 1988. a. rajoonikomitee II sekretäriks; kus ta viibis 2. veebruaril 1988. Lisa: Mida näitavad dokumendid

  19. MiDAS

    DEFF Research Database (Denmark)

    McIlroy, Simon Jon; Kirkegaard, Rasmus Hansen; McIlroy, Bianca

    A deep understanding of the microbial communities and dynamics in wastewater treatment systems is a powerful tool for process optimization and design (Rittmann et al., 2006). With the advent of amplicon sequencing of the 16S rRNA gene, the diversity within the microbial communities can now...... web platform about the microbes in activated sludge and their associated ADs. The MiDAS taxonomy proposes putative names for each genus-level-taxon that can be used as a common vocabulary for all researchers in the field....

  20. Vastused küsimustele, mida ei esitata / Kaupo Meiel

    Index Scriptorium Estoniae

    Meiel, Kaupo, 1975-

    2009-01-01

    Pärnu kirjastuse Jumalikud Ilmutused raamatutest: fs. Alasti ja elus (2008) ; Kaus, Jan. Miniatuurid (2009) ; Aru, Toomas F. Tahaks keppi Jääääre saatel, ehk, Georges Charles de Heeckeren d’Anthèsi pihtimus (2009)

  1. Vastused küsimustele, mida ei esitata / Kaupo Meiel

    Index Scriptorium Estoniae

    Meiel, Kaupo, 1975-

    2014-01-01

    Pärnu kirjastuse Jumalikud Ilmutused raamatutest: fs. Alasti ja elus (2008) ; Kaus, Jan. Miniatuurid (2009) ; Aru, Toomas F. Tahaks keppi Jääääre saatel, ehk, Georges Charles de Heeckeren d’Anthèsi pihtimus (2009)

  2. Osta seda, mida teised ei taha / Villu Zirnask

    Index Scriptorium Estoniae

    Zirnask, Villu, 1966-

    2005-01-01

    Investeerimisfondide analüüsiga tegelev firma Morningstar soovitab investoritel kasutada investeerimisstrateegiat, mis seisneb ebapopulaarsete investeerimisfondide osakute ostmises. Lisa: Kõige ebapopulaarsemad investeerimissektorid USA-s aastatel 1994-2004 (investeerimisfondide rahavoogude alusel)

  3. Raamat, mida ei tohiks olemas olla / Haljand Udam

    Index Scriptorium Estoniae

    Udam, Haljand, 1936-2005

    2005-01-01

    1919 Tartus H. Laakmanni trükikojas ilmunud broshüürist أJuudiusu saladused. أTalmutiؤ ja أSchulchan Aruchiؤ põhjal. Kuulsa asjatundja Dr. Eckerѫi läbi Trieri linna kohtus vandega tõeks tunnistatudؤ

  4. Mida tohib ja mida ei tohi teha teadlane / Toivo Maimets ; intervjueerinud Raivo Juurak

    Index Scriptorium Estoniae

    Maimets, Toivo, 1957-

    2009-01-01

    Intervjuu Tartu Ülikooli Molekulaar- ja Rakubioloogia Instituudi direktori, UNESCO rahvusvahelise bioeetika komitee aseesimehe professori Toivo Maimetsaga. Samas ka Oxfordi ülikooli professorist Richard Dawkinist

  5. The MIDAS Instrument Design and Characterization

    Science.gov (United States)

    Honniball, C. I.; Wright, R.; Lucey, P. G.

    2016-10-01

    The Miniaturized Infrared detector of Atmospheric Species (MIDAS) utilizes an uncooled microbolometer coupled with a Sagnac interferometer. MIDAS will be used to detect and quantify atmospheric constituents for a variety of science applications.

  6. Эстонский фильм взял приз на кинофестивале

    Index Scriptorium Estoniae

    2009-01-01

    Itaalias Trieste filmifestivalil tunnistati parimaks dokumentaalfilmiks ja omistati Alpe Adria Cinema preemia filmile "Revolutsioon, mida ei tulnud" (režissöör Aljona Polunina, produtsendid Ilkka Matila ja Jaak Kilmi; tootjad Kuukulgur Film ja Matila Röhr Productions Soomest, 2008)

  7. MIDAS Has the Golden Touch!

    Science.gov (United States)

    Yamashita, Irene

    1995-01-01

    Several CD-ROM products are being developed in Hawaii as part of MIDAS (Multimedia Industry for the Development of Academic Software), which helps promote technology in the classroom. The article examines how technology provides opportunities for students to develop higher thinking and problem-solving skills. (SM)

  8. Mida ootab lapsevanem? / Raivo Juurak

    Index Scriptorium Estoniae

    Juurak, Raivo, 1949-

    2009-01-01

    Eesti koostöö kogu programmijuht Mati Salundi ja Tallinna Ülikooli sotsiaaltöö instituudi dotsent Anne Tiko viisid möödunud kevadel läbi uuringu, kus selgitasid, mida ootavad 1. klassi astuvate laste vanemad lasteaialt, koolilt, õpetajalt, kohalikult omavalitsuselt. Uuringu tulemusi kommenteerisid vestlusringis Mati Salundi, Lastevanemate Liidu koolitusjuht Kristiine Vahtramäe ja uuringu retsensent, Tallinna Ülikooli kasvatusteaduse instituudi professor Marika Veisson

  9. MIDAS [Master Information and Data Acquisition System

    International Nuclear Information System (INIS)

    Ball, D.L.

    1986-01-01

    The Master Information and Data Acquisition System (MIDAS) is a computerized work control system that provides 24-hour, real-time access to plant equipment information and work package status. It is used in the 400 Area of the Department of Energy (DOE) Hanford Site in Richland, Washington. MIDAS was originally created to aid in the release and control of work at the Fast Flux Test Facility (FFTF), which is operated by the Westinghouse Hanford Company for the DOE. After MIDAS performed that function at FFTF successfully for over two years, its role was expanded to provide similar functions for other facilities supporting the LMR mission. Through its ability to provide online, accurate information on plant components, safety criteria, and work package status, MIDAS reinforces Operations functions and the control and authorization of maintenance activities in the FFTF plant and in other related facilities. Thus, MIDAS enhances the operational safety, as well as the planning and scheduling process for these facilities. MIDAS consists of three parts: The Plant Tracking System (PTS), the Work Control Log (WCL), and the MIDAS Component Indices

  10. MODELING HUMAN RELIABILITY ANALYSIS USING MIDAS

    Energy Technology Data Exchange (ETDEWEB)

    Ronald L. Boring; Donald D. Dudenhoeffer; Bruce P. Hallbert; Brian F. Gore

    2006-05-01

    This paper summarizes an emerging collaboration between Idaho National Laboratory and NASA Ames Research Center regarding the utilization of high-fidelity MIDAS simulations for modeling control room crew performance at nuclear power plants. The key envisioned uses for MIDAS-based control room simulations are: (i) the estimation of human error with novel control room equipment and configurations, (ii) the investigative determination of risk significance in recreating past event scenarios involving control room operating crews, and (iii) the certification of novel staffing levels in control rooms. It is proposed that MIDAS serves as a key component for the effective modeling of risk in next generation control rooms.

  11. Superconductivity in Spain. Midas program

    International Nuclear Information System (INIS)

    Yndurain, F.

    1996-01-01

    The different activities in the field of applied superconductivity carried out in Spain under the auspices of the MIDAS program are reported. Applications using both low- and high-temperature superconductors are considered. In the low temperature superconductors case, the design and construction of a 1 mega joule SMES (Superconducting Magnetic Energy Storage) unit, as well as the fabrication of voltage and resistance standards, are reviewed. Developments involving the design and fabrication of an inductive current fault limited and mono- and multi-filamentary wires and tapes using high-temperature superconductors are discussed. Finally, the prospects for the application of superconductivity technology to electric power systems for the electric utilities is considered. (author)

  12. Microwave detection of air showers with MIDAS

    Energy Technology Data Exchange (ETDEWEB)

    Facal San Luis, P., E-mail: facal@kicp.uchicago.edu [University of Chicago, Enrico Fermi Institue and Kavli Institute for Cosmological Physics, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Alekotte, I. [Centro Atomico Bariloche and Instituto Balseiro (CNEA-UNCuyo-CONICET), 8400 San Carlos de Bariloche, Rio Negro (Argentina); Alvarez, J. [Universidad de Santiago de Compostela, Departamento de Fisica de Particulas, Campus Sur, E-15782 Santiago de Compostela (Spain); Berlin, A. [University of Chicago, Enrico Fermi Institue and Kavli Institute for Cosmological Physics, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Bertou, X. [Centro Atomico Bariloche and Instituto Balseiro (CNEA-UNCuyo-CONICET), 8400 San Carlos de Bariloche, Rio Negro (Argentina); Bogdan, M.; Bohacova, M. [University of Chicago, Enrico Fermi Institue and Kavli Institute for Cosmological Physics, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Bonifazi, C. [Univ. Federal do Rio de Janeiro (UFRJ), Instituto de Fisica, Cidade Universitaria, Caixa Postal 68528, 21945-970 Rio de Janeiro, RJ (Brazil); Carvalho, W.R. [Universidad de Santiago de Compostela, Departamento de Fisica de Particulas, Campus Sur, E-15782 Santiago de Compostela (Spain); Mello Neto, J.R.T. de [Univ. Federal do Rio de Janeiro (UFRJ), Instituto de Fisica, Cidade Universitaria, Caixa Postal 68528, 21945-970 Rio de Janeiro, RJ (Brazil); Genat, J.F.; Mills, E.; Monasor, M.; Privitera, P.; Reyes, I.C.; Rouille d& #x27; Orfeuil, B. [University of Chicago, Enrico Fermi Institue and Kavli Institute for Cosmological Physics, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); and others

    2012-01-11

    MIDAS (MIcrowave Detector of Air Showers) is a prototype of a microwave telescope to detect extensive air showers: it images a 20{sup Degree-Sign } Multiplication-Sign 10{sup Degree-Sign} region of the sky with a 4.5 m parabolic reflector and 53 feeds in the focal plane. It has been commissioned in March 2010 and is currently taking data. We present the design, performance and first results of MIDAS.

  13. Microwave detection of air showers with MIDAS

    International Nuclear Information System (INIS)

    Facal San Luis, P.; Alekotte, I.; Alvarez, J.; Berlin, A.; Bertou, X.; Bogdan, M.; Bohacova, M.; Bonifazi, C.; Carvalho, W.R.; Mello Neto, J.R.T. de; Genat, J.F.; Mills, E.; Monasor, M.; Privitera, P.; Reyes, I.C.; Rouille d’Orfeuil, B.

    2012-01-01

    MIDAS (MIcrowave Detector of Air Showers) is a prototype of a microwave telescope to detect extensive air showers: it images a 20 ° ×10 ° region of the sky with a 4.5 m parabolic reflector and 53 feeds in the focal plane. It has been commissioned in March 2010 and is currently taking data. We present the design, performance and first results of MIDAS.

  14. Ei viitsi! / Aado Luik

    Index Scriptorium Estoniae

    Luik, Aado, 1937-

    2002-01-01

    Põhjus-tagajärg diagramm (Ishikawa diagramm) annab piltliku ülevaate põhjustest, miks õpilased ei viitsi õppida. Pareto diagramm kajastab näitlikult erinevate põhjuste osa halva tagajärje kujunemises

  15. The MIDAS Touch: Mixed Data Sampling Regression Models

    OpenAIRE

    Ghysels, Eric; Santa-Clara, Pedro; Valkanov, Rossen

    2004-01-01

    We introduce Mixed Data Sampling (henceforth MIDAS) regression models. The regressions involve time series data sampled at different frequencies. Technically speaking MIDAS models specify conditional expectations as a distributed lag of regressors recorded at some higher sampling frequencies. We examine the asymptotic properties of MIDAS regression estimation and compare it with traditional distributed lag models. MIDAS regressions have wide applicability in macroeconomics and �nance.

  16. MWIR hyperspectral imaging with the MIDAS instrument

    Science.gov (United States)

    Honniball, Casey I.; Wright, Rob; Lucey, Paul G.

    2017-02-01

    Hyperspectral imaging (HSI) in the Mid-Wave InfraRed (MWIR, 3-5 microns) can provide information on a variety of science applications from determining the chemical composition of lava lakes on Jupiter's moon Io, to investigating the amount of carbon liberated into the Earth's atmosphere during a wildfire. The limited signal available in the MWIR presents technical challenges to achieving high signal-to-noise ratios, and therefore it is typically necessary to cryogenically cool MWIR instruments. With recent improvements in microbolometer technology and emerging interferometric techniques, we have shown that uncooled microbolometers coupled with a Sagnac interferometer can achieve high signal-to-noise ratios for long-wave infrared HSI. To explore if this technique can be applied to the MWIR, this project, with funding from NASA, has built the Miniaturized Infrared Detector of Atmospheric Species (MIDAS). Standard characterization tests are used to compare MIDAS against a cryogenically cooled photon detector to evaluate the MIDAS instruments' ability to quantify gas concentrations. Atmospheric radiative transfer codes are in development to explore the limitations of MIDAS and identify the range of science objectives that MIDAS will most likely excel at. We will simulate science applications with gas cells filled with varying gas concentrations and varying source temperatures to verify our results from lab characterization and our atmospheric modeling code.

  17. A restructuring proposal for MIDAS

    International Nuclear Information System (INIS)

    Park, S. H.; Song, Y. M.; Kim, D. H.

    2000-01-01

    In order to develop a template for the MIDAS computer code, current data saving and transferring methods used in MELCOR are addressed first, and then a restructured module for the SPR package has been developed to be applied to MELCOR. The current MELCOR code ensures a fixed-size storage for four different data types, and manages the input-dependent data size by storing the data on the stacked packages. It uses pointer to identify the variables between the packages. This technique causes a difficult grasping of the meaning of the variables as well as waste of memory. New features of FORTRAN90, however, make it possible to allocate the storage dynamically and to use the user-defined data type, which lead to a restructured module development for the SPR package. An efficient memory treatment and an easy understanding of the code are the benefit from this developed module. The validation of the template has been done by comparing the results of the modified code with those from the existing code, and it is confirmed that the results are the same. The template for the SPR package hints the extension of the template to the entire code. It is expected that the template will accelerate the code domestication thanks to direct understanding of each variable and easy implementation of modified or newly developed models

  18. MIDAS - ESO's new image processing system

    Science.gov (United States)

    Banse, K.; Crane, P.; Grosbol, P.; Middleburg, F.; Ounnas, C.; Ponz, D.; Waldthausen, H.

    1983-03-01

    The Munich Image Data Analysis System (MIDAS) is an image processing system whose heart is a pair of VAX 11/780 computers linked together via DECnet. One of these computers, VAX-A, is equipped with 3.5 Mbytes of memory, 1.2 Gbytes of disk storage, and two tape drives with 800/1600 bpi density. The other computer, VAX-B, has 4.0 Mbytes of memory, 688 Mbytes of disk storage, and one tape drive with 1600/6250 bpi density. MIDAS is a command-driven system geared toward the interactive user. The type and number of parameters in a command depends on the unique parameter invoked. MIDAS is a highly modular system that provides building blocks for the undertaking of more sophisticated applications. Presently, 175 commands are available. These include the modification of the color-lookup table interactively, to enhance various image features, and the interactive extraction of subimages.

  19. MIDAS: an effective tool for work management

    International Nuclear Information System (INIS)

    Ball, D.L.; Billings, M.P.; McCargar, S.B.; Talbot, M.D.; Topping, C.F.

    1985-01-01

    The computerized Master Information Data Acquisition System (MIDAS) is used to control work at facilities that support the Liquid Metal Reactor (LMR) program on the Hanford Site at Richland, Washington. Functions of this software system are to: track authorized maintenance activities, enhance operational safety, track schedule, manpower, and material constraints during work preparation, provide a management tool for quality measurement techniques, and provide an overall repository for technical and safety-related information on components at the Hanford Site 400 Area facilities. This paper describes MIDAS and how it is used as a work management tool. 1 fig

  20. A New Python Library for Spectroscopic Analysis with MIDAS Style

    Science.gov (United States)

    Song, Y.; Luo, A.; Zhao, Y.

    2013-10-01

    The ESO MIDAS is a system for astronomers to analyze data which many astronomers are using. Python is a high level script language and there are many applications for astronomical data process. We are releasing a new Python library which realizes some MIDAS commands in Python. People can use it to write a MIDAS style Python code. We call it PydasLib. It is a Python library based on ESO MIDAS functions, which is easily used by astronomers who are familiar with the usage of MIDAS.

  1. Naine ei tohi, mida mees võib : Angela Marshall ei suutnud provotseerida ulatuslikku kunstiväitlust / Tõnis Erilaid

    Index Scriptorium Estoniae

    Erilaid, Tõnis, 1943-

    1998-01-01

    Los Angelese kunstniku Angela Marshalli näitus- müük Londonis Decima Gallerys. Kunstisündmus seisnes ostja portreteerimises, millele lisandus seksuaalakt. Piltide tegemisel kasutas kunstnik huulepulka.

  2. Suppurative peritonitis by Klebsiella pneumoniae in captive gold-handed tamarin (Saguinus midas midas).

    Science.gov (United States)

    Guerra, Maria F L; Teixeira, Rodrigo H F; Ribeiro, Vanessa L; Cunha, Marcos P V; Oliveira, Maria G X; Davies, Yamê M; Silva, Ketrin C; Silva, Ana P S; Lincopan, Nilton; Moreno, Andrea M; Knöbl, Terezinha

    2016-02-01

    This report describes an outbreak of suppurative peritonitis caused by Klebsiella pneumoniae in an adult female of captive golden-handed tamarin (Saguinus midas midas). Two virulent and multidrug-resistant strains were isolated and classified through MLST as ST60 and ST1263. The microbiological diagnosis works as a support tool for preventive measures. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Cointegrating MiDaS Regressions and a MiDaS Test

    OpenAIRE

    J. Isaac Miller

    2011-01-01

    This paper introduces cointegrating mixed data sampling (CoMiDaS) regressions, generalizing nonlinear MiDaS regressions in the extant literature. Under a linear mixed-frequency data-generating process, MiDaS regressions provide a parsimoniously parameterized nonlinear alternative when the linear forecasting model is over-parameterized and may be infeasible. In spite of potential correlation of the error term both serially and with the regressors, I find that nonlinear least squares consistent...

  4. Global EiBI-monopole

    Directory of Open Access Journals (Sweden)

    JIN Xinghua

    2014-04-01

    Full Text Available A global EiBI-monopole problem is studied under EiBI gravitational theory.The equations of global EiBI-monopole are derived in the curved spacetime and the relation between the spacetime metric and auxiliary metric is found.In the case of a very small parameter,an asymptotic form of equations is given.The series solutions of global EiBI-monopole at infinity are found.

  5. Modeling human reliability analysis using MIDAS

    International Nuclear Information System (INIS)

    Boring, R. L.

    2006-01-01

    This paper documents current efforts to infuse human reliability analysis (HRA) into human performance simulation. The Idaho National Laboratory is teamed with NASA Ames Research Center to bridge the SPAR-H HRA method with NASA's Man-machine Integration Design and Analysis System (MIDAS) for use in simulating and modeling the human contribution to risk in nuclear power plant control room operations. It is anticipated that the union of MIDAS and SPAR-H will pave the path for cost-effective, timely, and valid simulated control room operators for studying current and next generation control room configurations. This paper highlights considerations for creating the dynamic HRA framework necessary for simulation, including event dependency and granularity. This paper also highlights how the SPAR-H performance shaping factors can be modeled in MIDAS across static, dynamic, and initiator conditions common to control room scenarios. This paper concludes with a discussion of the relationship of the workload factors currently in MIDAS and the performance shaping factors in SPAR-H. (authors)

  6. Yet another look at MIDAS regression

    NARCIS (Netherlands)

    Ph.H.B.F. Franses (Philip Hans)

    2016-01-01

    textabstractA MIDAS regression involves a dependent variable observed at a low frequency and independent variables observed at a higher frequency. This paper relates a true high frequency data generating process, where also the dependent variable is observed (hypothetically) at the high frequency,

  7. Microwave detection of air showers with MIDAS

    Czech Academy of Sciences Publication Activity Database

    Facal San Luis, P.; Alekotte, I.; Alvarez, J.; Berlin, A.; Bertou, X.; Bogdan, M.; Boháčová, Martina; Bonifazi, C.; Carvalho, W.R.; de Mello Neto, J.R.T.; Genat, J.F.; Mills, E.; Monasor, M.; Privitera, P.; Reyes, I.C.; d´Orfeuil, B.R.; Santos, E.M.; Wayne, S.; Williams, C.; Zas, E.

    2012-01-01

    Roč. 662, Sup. 1 (2012), "S118"-"S123" ISSN 0168-9002 R&D Projects: GA MŠk(CZ) LA08016 Institutional research plan: CEZ:AV0Z10100502 Keywords : MIDAS (Microwave Detector of Air Showers) * extensive air showers Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 1.142, year: 2012

  8. Engineering Information System (EIS)

    Science.gov (United States)

    1992-01-31

    be availabe and usefu for creating powerful tailored contro and mangeen functions. Mode and Framwork Wirth further elaboration of the EIS portio of...control data and activities of the engineering process. The EIM is a conceptual model of administrative and electroic design information. It records...of the access opeations are derived from the instance variable name and type. An attribute conceptually holds one or more instances of a basic type

  9. Molecular Isotopic Distribution Analysis (MIDAs) with adjustable mass accuracy.

    Science.gov (United States)

    Alves, Gelio; Ogurtsov, Aleksey Y; Yu, Yi-Kuo

    2014-01-01

    In this paper, we present Molecular Isotopic Distribution Analysis (MIDAs), a new software tool designed to compute molecular isotopic distributions with adjustable accuracies. MIDAs offers two algorithms, one polynomial-based and one Fourier-transform-based, both of which compute molecular isotopic distributions accurately and efficiently. The polynomial-based algorithm contains few novel aspects, whereas the Fourier-transform-based algorithm consists mainly of improvements to other existing Fourier-transform-based algorithms. We have benchmarked the performance of the two algorithms implemented in MIDAs with that of eight software packages (BRAIN, Emass, Mercury, Mercury5, NeutronCluster, Qmass, JFC, IC) using a consensus set of benchmark molecules. Under the proposed evaluation criteria, MIDAs's algorithms, JFC, and Emass compute with comparable accuracy the coarse-grained (low-resolution) isotopic distributions and are more accurate than the other software packages. For fine-grained isotopic distributions, we compared IC, MIDAs's polynomial algorithm, and MIDAs's Fourier transform algorithm. Among the three, IC and MIDAs's polynomial algorithm compute isotopic distributions that better resemble their corresponding exact fine-grained (high-resolution) isotopic distributions. MIDAs can be accessed freely through a user-friendly web-interface at http://www.ncbi.nlm.nih.gov/CBBresearch/Yu/midas/index.html.

  10. Arhitektuur, mida (veel) ei näe ega kuule / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2009-01-01

    11. rahvusvaheline Alvar Aalto sümpoosion Jyväskyläs Soomes teemal "Edge - Paracentric arhitecture". Linnadest ilma arhitektuurita, arhitektuurist geograafilistel äärealadel, arhitektidest-ehitusmeistritest, kogukonnakesksest ja kaasavast arhitektuurist. Kuidas olla arhitekt maal, kus pea kõik ehitatakse arhitekti abita. Kuraaror Sami Rintala vastused neljale küsimusele

  11. Uned, mida mujal ei näe / Heilika Võsu ; interv. Mari Laaniste

    Index Scriptorium Estoniae

    Võsu, Heilika

    2007-01-01

    PÖFFi animafilmide festivali "Animated Dreams" (21.-25. XI kinos Sõprus), mis on seekord pühendatud Nukufilmi 50. juubelile, tutvustab festivali peakorraldaja. Võistluskavas on Eestist Kaspar Jancise "Maraton" ja Mari-Liis Bassovskaja - Jelena Girlini "Kleit". Lisatud festivali kava

  12. "Mida mina ei julge, teeb Homer filmis ära!" / Katrin Pauts

    Index Scriptorium Estoniae

    Pauts, Katrin, 1977-

    2007-01-01

    21. juulil on joonisfilmi "Simpsonite film" ("The Simpsons Movie") maailmaesilinastus. Seriaali suur fänn, saatejuht Kristjan Jõekalda sellest, miks talle Simpsonid meeldivad. Lisaks "Marge'i juuksed on inspireeritud Frankenteini pruudist"

  13. Mis oli ja mida ei olnud : lisandusi kahele kirjutisele / Tiiu Erelt

    Index Scriptorium Estoniae

    Erelt, Tiiu, 1942-

    2008-01-01

    Lisandusi artiklitele: Koppel, Margit-Mariann. Mahalaskmine pärast surma //Eesti Ekspress, 23. aug. 2007, mis käsitleb Elmar Muugi saatust, ning: Raag, Raimo. Valter Tauli elust ja keelelisest tegevusest // Keel ja Kirjandus, (2007/Nov), nr. 11

  14. Trichtlinnburg tõi esile asjad, mida turist ei näe / Liina Siib

    Index Scriptorium Estoniae

    Siib, Liina

    2005-01-01

    Ajaloolise linnaruumi säilitamist ja arendamist uuriva Euroopa kultuuriprojekti Trichtlinnburg (TLB) Tallinnas toimunud kunstiprojektidest. Sanja Ivekovici video "(If) I Lived Here", Silja Saarepuu ja Villu Plingi objekt "Plats", Anna-Karin Stjerlofi näidispostkaardid, Jüri Ojaveri projekt "Pääsla", Tiina Tammetalu projekt "Seirajad", Katrin Essensoni ja Helen Becki performance'id, David Bate'i fotosari, TLB jalutuskäigud Tallinnas

  15. Mida teha, et lapsed koolist ei puuduks? / Triin Tomingas, Hille Hinsberg, Sirje Ess...[jt

    Index Scriptorium Estoniae

    2011-01-01

    Küsimusele vastavad lapsevanemad Triin Tomingas ja Hille Hinsberg, Saaremaa ühisgümnaasiumi algklasside õppealajuhataja Sirje Ess, Tallinna Pelgulinna gümnaasiumi direktor Tõnu Piibur, MTÜ Ellu psühholoog-koolitaja Tiia Lister

  16. Elu nagu filmis - ainult selline, mida te endale ei sooviks / Eva Kübar

    Index Scriptorium Estoniae

    Kübar, Eva

    2009-01-01

    20.-25. jaanuarini toimunud Helsingi dokumentaalfilmifestival DocPoint. Eesti filmidest oli festivalil Meelis Muhu "Aljoša". Pikemalt India filmist "India kuningas" ("King of India", režissöör Arvind Sinha), Uus-Meremaa filmist "Staarikunstnik ning sudaani kaksikud" ("The Art Star and the Sudanese twins", režissöör Pietra Brettkelly)

  17. MIDAS: Regionally linear multivariate discriminative statistical mapping.

    Science.gov (United States)

    Varol, Erdem; Sotiras, Aristeidis; Davatzikos, Christos

    2018-07-01

    Statistical parametric maps formed via voxel-wise mass-univariate tests, such as the general linear model, are commonly used to test hypotheses about regionally specific effects in neuroimaging cross-sectional studies where each subject is represented by a single image. Despite being informative, these techniques remain limited as they ignore multivariate relationships in the data. Most importantly, the commonly employed local Gaussian smoothing, which is important for accounting for registration errors and making the data follow Gaussian distributions, is usually chosen in an ad hoc fashion. Thus, it is often suboptimal for the task of detecting group differences and correlations with non-imaging variables. Information mapping techniques, such as searchlight, which use pattern classifiers to exploit multivariate information and obtain more powerful statistical maps, have become increasingly popular in recent years. However, existing methods may lead to important interpretation errors in practice (i.e., misidentifying a cluster as informative, or failing to detect truly informative voxels), while often being computationally expensive. To address these issues, we introduce a novel efficient multivariate statistical framework for cross-sectional studies, termed MIDAS, seeking highly sensitive and specific voxel-wise brain maps, while leveraging the power of regional discriminant analysis. In MIDAS, locally linear discriminative learning is applied to estimate the pattern that best discriminates between two groups, or predicts a variable of interest. This pattern is equivalent to local filtering by an optimal kernel whose coefficients are the weights of the linear discriminant. By composing information from all neighborhoods that contain a given voxel, MIDAS produces a statistic that collectively reflects the contribution of the voxel to the regional classifiers as well as the discriminative power of the classifiers. Critically, MIDAS efficiently assesses the

  18. Assessing the ecosystem effects of the abalone Haliotis midae from ...

    African Journals Online (AJOL)

    Assessing the ecosystem effects of the abalone Haliotis midae from its diet and foraging ... midae is commercially exploited and seriously threatened by overfishing. ... of the ecosystem because of associated changes in community structure. ... of this previously abundant herbivore on the south-west coast of South Africa, we ...

  19. Shaping the manufacturing industry performance: MIDAS approach

    International Nuclear Information System (INIS)

    Turhan, Ibrahim M.; Sensoy, Ahmet; Hacihasanoglu, Erk

    2015-01-01

    We aim to find out whether the exchange rate (against US dollar) or the interest rate (in local currency) is a better variable in predicting the capacity utilization rate of manufacturing industry (CUR) of Turkey after the 2008 global financial crisis. In that manner, we implement dynamic mixed data sampling (MIDAS) regression model to forecast monthly changes in CUR by using daily changes in the exchange rate and the interest rate separately. The results show that exchange rate has a better forecast performance suggesting that it is a stronger determinant in shaping the manufacturing industry

  20. MIDAS/PK code development using point kinetics model

    International Nuclear Information System (INIS)

    Song, Y. M.; Park, S. H.

    1999-01-01

    In this study, a MIDAS/PK code has been developed for analyzing the ATWS (Anticipated Transients Without Scram) which can be one of severe accident initiating events. The MIDAS is an integrated computer code based on the MELCOR code to develop a severe accident risk reduction strategy by Korea Atomic Energy Research Institute. In the mean time, the Chexal-Layman correlation in the current MELCOR, which was developed under a BWR condition, is appeared to be inappropriate for a PWR. So as to provide ATWS analysis capability to the MIDAS code, a point kinetics module, PKINETIC, has first been developed as a stand-alone code whose reference model was selected from the current accident analysis codes. In the next step, the MIDAS/PK code has been developed via coupling PKINETIC with the MIDAS code by inter-connecting several thermal hydraulic parameters between the two codes. Since the major concern in the ATWS analysis is the primary peak pressure during the early few minutes into the accident, the peak pressure from the PKINETIC module and the MIDAS/PK are compared with the RETRAN calculations showing a good agreement between them. The MIDAS/PK code is considered to be valuable for analyzing the plant response during ATWS deterministically, especially for the early domestic Westinghouse plants which rely on the operator procedure instead of an AMSAC (ATWS Mitigating System Actuation Circuitry) against ATWS. This capability of ATWS analysis is also important from the view point of accident management and mitigation

  1. Saksa parlament ei karda moodsat kunsti

    Index Scriptorium Estoniae

    1999-01-01

    Pärast aastavahetust kolisid Saksa seadusandlikud organid Bonnist Berliini Reichstagi hoonesse, mida renoveerib briti arhitekt Norman Foster. Ajalooline ehitis kavatsetakse täita rahvusvaheliselt tuntud kunstnike loominguga. Autorite väljavalimisega tegeleva organi koosseis

  2. The Steady State Calculation for SMART with MIDAS/SMR

    International Nuclear Information System (INIS)

    Park, Jong Hwa; Kim, Dong Ha; Chung, Young Jong; Park, Sun Hee; Cho, Seong Won

    2010-01-01

    KAERI is developing a new concept of reactor that all the main components such as the steam generator, the coolant pumps and the pressurizer are located inside the reactor vessel. Before the severe accident sequences are estimated, it is prerequisite that MIDAS code predicts the steady state conditions properly. But MIDAS code does not include the heat transfer model for the helical tube. Therefore, the heat transfer models for the helical tube from TASS/SMR-S were implemented into MIDAS code. To estimate the validity of the implemented heat transfer correlations for the helical tube and the input data, the steady state was recalculated with MIDAS/SMR based on design level 2 and compared with the design values

  3. Erapooletuid ei olnud / Reet Roos

    Index Scriptorium Estoniae

    Roos, Reet, 1973-

    2006-01-01

    Menetlusest langes välja eelnõu, mille mõte oli, et riik tagaks elatise lapsele, kelle ühelt vanemalt on elatis kohtulikult välja mõistetud, kuid kes seda ise maksta ei taha või ei saa. Sama ka Koit 23. mai 2006, lk. 6 ; Valgamaalane 23. mai 2006, lk. 2 ; Järva Teataja 23. mai 2006, lk. 2 ; Elva Postipoiss 20. mai 2006, lk. 2 ; Vooremaa 16. mai 2006, lk. 2 ; Vali Uudised 17. mai 2006, lk. 2 ; Nädaline 16. mai 2006, lk. 2

  4. President ei pruugi uuesti kandideerida

    Index Scriptorium Estoniae

    2006-01-01

    Proua Ingrid Rüütel viitas Kanal 2 uudistesaates "Reporter" võimalusele, et Arnold Rüütel enam uueks ametiajaks ei kandideeri. Ilmunud ka Eesti Päevaleht, 2006/Mar/1, lk. 5 ; Koit, 2006/Mar/2, lk. 2

  5. EL : Iiri "ei" Lissaboni lepingut ei surmanud / Kaivo Kopli

    Index Scriptorium Estoniae

    Kopli, Kaivo

    2008-01-01

    Iirlased hääletasid Lissaboni lepingu vastu. EL-i välisministrite nõupidamisel Luksemburgis ütles Iiri välisminister, et rahva tahet tuleb austada. Enamik EL-i riike soovib, et lepingu ratifitseeriksid ka need riigid, kes pole veel seda teinud, Tšehhi asepeaministri Alexander Vondra on seisukohal, et riikidele ei tohi survet avaldada. Vt. samas: Pariis süüdistab juba Brüsselit

  6. Development of GUI systems for the MIDAS code

    International Nuclear Information System (INIS)

    Kim, K.R.; Park, S.H.; Kim, D.H.

    2004-01-01

    MIDAS is being developed at KAERI based on MELCOR as an integrated severe accident analysis code with existing model modification and new model addition. MIDAS was restructured to avoid the pointer based variable referencing style of MELCOR, and enhanced the memory effectiveness using the dynamic allocation method of Fortran 90. This paper describes recent activities of developing the GUI environments for MIDAS code at KAERI. Up to now, we have developed the four PC-based subsystems, which are IEDIT, IPLOT, SATS and HyperKAMG. IEDIT is an input management system that can read MELCOR input files and display its information in the Window panels. Users can modify each item in the panel and the input file will be modified according to that changes. IPLOT is a simple plotting system that can draw MIDAS plot variables trend graphs. SATS is developed as a severe accident training simulator that can display nuclear plant behavior graphically. Moreover SATS provides several controllable pumps and valves which appeared in the severe accidence. Together with SATS and the online severe accident guidance HyperKAMG, combined properly, severe accident mitigation scenarios could be presented graphically and dramatically without any change of MELCOR inputs. GUI development as a part of a severe accident management program package, MIDAS. (author)

  7. Mokken scaling of the Myocardial Infarction Dimensional Assessment Scale (MIDAS).

    Science.gov (United States)

    Thompson, David R; Watson, Roger

    2011-02-01

    The purpose of this study was to examine the hierarchical and cumulative nature of the 35 items of the Myocardial Infarction Dimensional Assessment Scale (MIDAS), a disease-specific health-related quality of life measure. Data from 668 participants who completed the MIDAS were analysed using the Mokken Scaling Procedure, which is a computer program that searches polychotomous data for hierarchical and cumulative scales on the basis of a range of diagnostic criteria. Fourteen MIDAS items were retained in a Mokken scale and these items included physical activity, insecurity, emotional reaction and dependency items but excluded items related to diet, medication or side-effects. Item difficulty, in item response theory terms, ran from physical activity items (low difficulty) to insecurity, suggesting that the most severe quality of life effect of myocardial infarction is loneliness and isolation. Items from the MIDAS form a strong and reliable Mokken scale, which provides new insight into the relationship between items in the MIDAS and the measurement of quality of life after myocardial infarction. © 2010 Blackwell Publishing Ltd.

  8. Muutuv kommunikatsioon kultuuri ei ohusta / Annika Poldre

    Index Scriptorium Estoniae

    Poldre, Annika

    2011-01-01

    Tallinna Konverentside poolt Sokos Hotel Virus 28. aprillil 2011 korraldatud kommunikatsiooni aastakonverentsist "Muutuv kommunikatsioon: vana ei taha ja uut ei oska. Kuidas edasi?", kus esinesid Ahto Lobjakas, Priit Põiklik, Piia Tamm ja Marju Lauristin

  9. Sajand hiljem. Mida Noor-Eesti tegi ja mida ta ei teinud. A Century Later: What Young Estonia Did – and What it Did Not Do

    Directory of Open Access Journals (Sweden)

    Cornelius Hasselblatt

    2012-04-01

    Full Text Available This article discusses the position of Young Estonia (Noor-Eesti in four different fields of influence: 1. What is the position of the Young Estonia movement in literary history, i.e. in the different monographs and articles on Estonian literature? What position is given to the movement by the writer(s of the various sketches on Estonian literature between 1908 and 2007, and how important are the writers of the group in the eyes of literary historians? 2. How is the movement represented in the collective (public memory of Estonia, e.g. do we find members of the movement on stamps or banknotes or in street names? 3. How do people in Estonia remember the literary production of the members of the group: what are the most important texts people read today, and how are these texts linked to the Young Estonia movement? 4. Finally, how is the movement represented outside Estonia, i.e. in the reception of Estonian literature abroad? Which texts have been translated, which authors are well-known abroad? In answering these questions the author concludes that the Young Estonia movement was much less important than has been assumed with respect to the production of literature, i.e. yielding literary texts that have been recognized and read up till the present. Rather, the lasting importance of Young Estonia has been in the organization of literary life.

  10. MIDAS questionnaire modification for a new MIDAS junior questionnaire: a clinical experience at the Neurological Institute "C. Besta".

    Science.gov (United States)

    Grazzi, L

    2004-10-01

    During the last decade researchers have begun to employ standardised methodologies to investigate the global impact of primary headaches. Disease-specific instruments have been developed to measure headache-related disability. The MIDAS questionnaire, which is the most extensively studied of these instruments, was designed to assess the overall impact of headaches over the 3 months before compilation. The MIDAS questionnaire is an optimal tool to assess headache-related disability in adults in relation to patients' daily activities. Primary headaches are a recurrent problem for children and adolescents. Forty percent of children have experienced headaches by the age of 7 years increasing to 75% by the age of 15. In a recent report we determined the suitability of the MIDAS questionnaire in its original form for assessing disability in children and adolescents suffering from different kinds of headache. This was the first step of a line of research aimed to develop a new MIDAS questionnaire adapted for young patients. In this second study the aims were: (1) to produce a new version of the MIDAS questionnaire specific for young patients suffering from different forms of headache; (2) to assess the reliability of this new instrument; (3) to assess its sensitivity to treatment intervention.

  11. Applications of MIDAS regression in analysing trends in water quality

    Science.gov (United States)

    Penev, Spiridon; Leonte, Daniela; Lazarov, Zdravetz; Mann, Rob A.

    2014-04-01

    We discuss novel statistical methods in analysing trends in water quality. Such analysis uses complex data sets of different classes of variables, including water quality, hydrological and meteorological. We analyse the effect of rainfall and flow on trends in water quality utilising a flexible model called Mixed Data Sampling (MIDAS). This model arises because of the mixed frequency in the data collection. Typically, water quality variables are sampled fortnightly, whereas the rain data is sampled daily. The advantage of using MIDAS regression is in the flexible and parsimonious modelling of the influence of the rain and flow on trends in water quality variables. We discuss the model and its implementation on a data set from the Shoalhaven Supply System and Catchments in the state of New South Wales, Australia. Information criteria indicate that MIDAS modelling improves upon simplistic approaches that do not utilise the mixed data sampling nature of the data.

  12. Käsikirju ei tule / Jaanus Noormets

    Index Scriptorium Estoniae

    Noormets, Jaanus

    2007-01-01

    12 000 Hollywoodi stsenaristi (Writers Guild of America) streigivad novembri algusest USA filmi- ja teletööstuse vastu. Streigi võimalikest tagajärgedest ameerika meelelahutustööstusele. Lisatud ülevaade nende telesarjade saatusest, mida näidatakse praegu Eesti telekanalites

  13. Development of MIDAS/SMR Input Deck for SMART

    International Nuclear Information System (INIS)

    Cho, S. W.; Oh, H. K.; Lee, J. M.; Lee, J. H.; Yoo, K. J.; Kwun, S. K.; Hur, H.

    2010-01-01

    The objective of this study is to develop MIDAS/SMR code basic input deck for the severe accidents by simulating the steady state for the SMART plant. SMART plant is an integrated reactor developed by KAERI. For the assessment of reactor safety and severe accident management strategy, it is necessary to simulate severe accidents using the MIDAS/SMR code which is being developed by KAERI. The input deck of the MIDAS/SMR code for the SMART plant is prepared to simulate severe accident sequences for the users who are not familiar with the code. A steady state is obtained and the results are compared with design values. The input deck will be improved through the simulation of the DBAs and severe accidents. The base input deck of the MIDAS/SMR code can be used to simulate severe accident scenarios after improvement. Source terms and hydrogen generation can be analyzed through the simulation of the severe accident. The information gained from analyses of severe accidents is expected to be helpful to develop the severe accident management strategy

  14. MIDAS: A Modular DNA Assembly System for Synthetic Biology.

    Science.gov (United States)

    van Dolleweerd, Craig J; Kessans, Sarah A; Van de Bittner, Kyle C; Bustamante, Leyla Y; Bundela, Rudranuj; Scott, Barry; Nicholson, Matthew J; Parker, Emily J

    2018-04-20

    A modular and hierarchical DNA assembly platform for synthetic biology based on Golden Gate (Type IIS restriction enzyme) cloning is described. This enabling technology, termed MIDAS (for Modular Idempotent DNA Assembly System), can be used to precisely assemble multiple DNA fragments in a single reaction using a standardized assembly design. It can be used to build genes from libraries of sequence-verified, reusable parts and to assemble multiple genes in a single vector, with full user control over gene order and orientation, as well as control of the direction of growth (polarity) of the multigene assembly, a feature that allows genes to be nested between other genes or genetic elements. We describe the detailed design and use of MIDAS, exemplified by the reconstruction, in the filamentous fungus Penicillium paxilli, of the metabolic pathway for production of paspaline and paxilline, key intermediates in the biosynthesis of a range of indole diterpenes-a class of secondary metabolites produced by several species of filamentous fungi. MIDAS was used to efficiently assemble a 25.2 kb plasmid from 21 different modules (seven genes, each composed of three basic parts). By using a parts library-based system for construction of complex assemblies, and a unique set of vectors, MIDAS can provide a flexible route to assembling tailored combinations of genes and other genetic elements, thereby supporting synthetic biology applications in a wide range of expression hosts.

  15. HIT-6 and MIDAS as measures of headache disability in a headache referral population.

    Science.gov (United States)

    Sauro, Khara M; Rose, Marianne S; Becker, Werner J; Christie, Suzanne N; Giammarco, Rose; Mackie, Gordon F; Eloff, Arnoldas G; Gawel, Marek J

    2010-03-01

    The objective of this study was to compare the headache impact test (HIT-6) and the migraine disability assessment scale (MIDAS) as clinical measures of headache-related disability. The degree of headache-related disability is an important factor in treatment planning. Many quality of life and headache disability measures exist but it is unclear which of the available disability measures is the most helpful in planning and measuring headache management. We compared HIT-6 and MIDAS scores from 798 patients from the Canadian Headache Outpatient Registry and Database (CHORD). Correlation and regression analyses were used to examine the relationships between the HIT-6 and MIDAS total scores, headache frequency and intensity, and Beck Depression Inventory (BDI-II) scores. A positive correlation was found between HIT-6 and MIDAS scores (r = 0.52). The BDI-II scores correlated equally with the HIT-6 and the MIDAS (r = 0.42). There was a non-monotonic relationship between headache frequency and the MIDAS, and a non-linear monotonic relationship between headache frequency and the HIT-6 (r = 0.24). The correlation was higher between the intensity and the HIT-6 scores (r = 0.46), than MIDAS (r = 0.26) scores. Seventy-nine percent of patients fell into the most severe HIT-6 disability category, compared with the 57% of patients that fell into the most severe MIDAS disability category. Significantly more patients were placed in a more severe category with the HIT-6 than with the MIDAS (McNemar chi-square = 191 on 6 d.f., P MIDAS appear to measure headache-related disability in a similar fashion. However, some important differences may exist. Headache intensity appears to influence HIT-6 score more than the MIDAS, whereas the MIDAS was influenced more by headache frequency. Using the HIT-6 and MIDAS together may give a more accurate assessment of a patient's headache-related disability.

  16. OpenEIS. Developer Guide

    Energy Technology Data Exchange (ETDEWEB)

    Lutes, Robert G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Neubauer, Casey C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Haack, Jereme N. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Carpenter, Brandon J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Monson, Kyle E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Allwardt, Craig H. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Sharma, Poorva [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Akyol, Bora A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-03-31

    The Department of Energy’s (DOE’s) Building Technologies Office (BTO) is supporting the development of an open-source software tool for analyzing building energy and operational data: OpenEIS (open energy information system). This tool addresses the problems of both owners of building data and developers of tools to analyze this data. Building owners and managers have data but lack the tools to analyze it while tool developers lack data in a common format to ease development of reusable data analysis tools. This document is intended for developers of applications and explains the mechanisms for building analysis applications, accessing data, and displaying data using a visualization from the included library. A brief introduction to the visualizations can be used as a jumping off point for developers familiar with JavaScript to produce their own. Several example applications are included which can be used along with this document to implement algorithms for performing energy data analysis.

  17. A MARS and MIDAS Linked Accident Simulation for Large LOCA in APR1400

    International Nuclear Information System (INIS)

    Choi, Young; Kim, K. R.; Kim, D. H.; Chung, B. D.

    2006-01-01

    A linked calculation utilizing the design-basis code MARS and the severe accident code MIDAS has been accomplished for a station blackout simulation in APR1400. The MARS code was developed by using the RELAP3/MOD3 and COBRA-TF codes, while the MIDAS code is currently under a development process using the MELCOR code. The objectives of this paper are to explain how to identify the MAR-MIDAS linked calculation outlines and the technical problems, including the MARS data transfer method, the MIDAS input generation works and so on. For the performance verification of the MARS-MIDAS linked calculation, the MARS, MIDAS and their linkage system are run independently for the same initiating event, so that their data can be compared with each other after the selection of proper variables

  18. Development of the GUI environments of MIDAS code for convenient input and output processing

    International Nuclear Information System (INIS)

    Kim, K. L.; Kim, D. H.

    2003-01-01

    MIDAS is being developed at KAERI as an integrated Severe Accident Analysis Code with easy model modification and addition by restructuring the data transfer scheme. In this paper, the input file management system, IEDIT and graphic simulation system, SATS, are presented as MIDAS input and output GUI systems. These two systems would form the basis of the MIDAS GUI system for input and output processing, and they are expected to be useful tools for severe accidents analysis and simulation

  19. Ameerika ei ole Jaapan / Michael Craig

    Index Scriptorium Estoniae

    Craig, Michael

    2002-01-01

    Kuidas Jaapani ärimees Minoru Isutani 1981. aastal ei arvestnud, et ameeriklased ei osta golfiklubi eluaegset liikmekaarti 750 000 dollari eest, ning kaotas USA kuulsaima Pebble Beachi golfiväljaku. Katkend raamatust "50 parimat ja halvimat tehingut läbi aegade"

  20. 32 CFR 989.20 - Final EIS.

    Science.gov (United States)

    2010-07-01

    ... limited to factual corrections and responses to comments, the proponent and EPF may, with the prior..., the EPF must submit the Draft EIS and all of the above documents, with a new cover sheet indicating... more extensive modifications are required, the EPF must prepare a preliminary final EIS incorporating...

  1. Mida teha, et kirikukäsiraamat meie kirikut ei lõhuks? / Thomas-Andreas Põder

    Index Scriptorium Estoniae

    Põder, Thomas-Andreas, 1976-

    2009-01-01

    Kirikukäsiraamatu esialgse redaktsiooni esitlus oli meie kirikuelus kahemõtteline sündmus: raamatu trükist ilmumine ja asjaosaliste tänamine oli rõõmustav, selle esitlemine lõpuleviidud tööna kurvastav

  2. Scientific applications and numerical algorithms on the midas multiprocessor system

    International Nuclear Information System (INIS)

    Logan, D.; Maples, C.

    1986-01-01

    The MIDAS multiprocessor system is a multi-level, hierarchial structure designed at the Advanced Computer Architecture Laboratory of the University of California's Lawrence Berkeley Laboratory. A two-stage, 11-processor system has been operational for over a year and is currently undergoing expansion. It has been employed to investigate the performance of different methods of decomposing various problems and algorithms into a multiprocessor environment. The results of such tests on a variety of applications such as scientific data analysis, Monte Carlo calculations, and image processing, are discussed. Often such decompositions involve investigating the parallel structure of fundamental algorithms. Several basic algorithms dealing with random number generation, matrix diagonalization, fast Fourier transforms, and finite element methods in solving partial differential equations are also discussed. The performance and projected extensibilities of these decompositions on the MIDAS system are reported

  3. Operating system considerations in the multiprocessor MIDAS environment

    International Nuclear Information System (INIS)

    Weaver, D.; Maples, C.; Meng, J.; Rathbun, W.

    1983-01-01

    The operating system for MIDAS provides interfaces for custom hardware, debugging facilities, and run time support. The MIDAS architecture uses various specialized hardware devices for controlling the multiple processors and to achieve high I/O throughput. The operating system interfaces with the custom hardware for diagnostics, problem setup, and loading the processors with user code. After the code is loaded, a debugging facility may be used to examine or modify the program in any of the processors, or all the processors simultaneously. During execution of the code, the operating system monitors the processors for exceptional conditions, detects hardware failures, and gathers statistics on performance. This performance information includes histograms depicting instruction execution frequency and analysis of data flow

  4. Mida vähem, seda parem / Kaia Lehari

    Index Scriptorium Estoniae

    Lehari, Kaia, 1944-

    1998-01-01

    Funktsionalismist, teisenemistest aastail 1920-1960. Esindajaid : W. Gropius, L. Mies van der Rohe, Le Corbusier. Modernismist. Konstruktivismist (arhitektid vennad Vesninid, disainerid A. Rodtshenko, E. Lissitsky, V. Tatlin) ja ratsionaalse esteetika suunast (arhitektid N. A. Ladovski, K. Melnikov) Venemaal. Koolidest Bauhaus Saksamaal ja Vhutemas-Vhutein Venemaal. Bauhausi stiilist, mida pärast II Maailmasõda internatsionaalseks stiiliks nimetama hakati. Funktsionalismi näiteid Eestist: O. Siinmaa, E. Habermanni, H. Johansoni tööd

  5. Ilves : mida põrgut teeb Venemaa G8-s?

    Index Scriptorium Estoniae

    2007-01-01

    President Toomas Hendrik Ilves viibis Prahas 4. ja 5. juunil 2007 toimunud konverentsil "Demokraatia ja julgeolek", kus ta seadis kahtluse alla selle, kas Euroopat rakettidega ähvardava Venemaa koht on ikka G8-s ja Euroopa Nõukogus. Ilmunud ka: Eesti Elu 8. juuni 2007, lk. 1,4, pealk.: Mida teeb Venemaa G8-s?, ingl. k. lk. 9, pealk.: Ilves: what is Russia doing in the G8? Vabariigi President töövisiidil Prahasse 4.-6.06.2007

  6. Operation and maintenance manual for data acquisition system of MIDAS

    International Nuclear Information System (INIS)

    Lee, D. Y.; Park, W. M.; Kim, J. T.; Euh, D. J.

    2001-09-01

    This report describes an operation and maintenance manual of the data acquisition system and the data processing system for the DVI performance evaluation facility, MIDAS. The data acquisition system is implemented with VXI based system of Kinetic Systems TM , and the data processing PC. This report presents the configuration method and operation procedure for the operator. The modification procedure and method for functional extension and performance modification are also included for the future demand

  7. Microwave detection of air showers with the MIDAS experiment

    International Nuclear Information System (INIS)

    Privitera, Paolo; Alekotte, I.; Alvarez-Muniz, J.; Berlin, A.; Bertou, X.; Bogdan, M.; Bohacova, M.; Bonifazi, C.; Carvalho, W.R.; Mello Neto, J.R.T. de; Facal San Luis, P.; Genat, J.F.; Hollon, N.; Mills, E.; Monasor, M.; Reyes, L.C.; Rouille d'Orfeuil, B.; Santos, E.M.; Wayne, S.; Williams, C.

    2011-01-01

    Microwave emission from Extensive Air Showers could provide a novel technique for ultra-high energy cosmic rays detection over large area and with 100% duty cycle. We describe the design, performance and first results of the MIDAS (MIcrowave Detection of Air Showers) detector, a 4.5 m parabolic dish with 53 feeds in its focal plane, currently installed at the University of Chicago.

  8. MIDA - Optimizing control room performance through multi-modal design

    International Nuclear Information System (INIS)

    Ronan, A. M.

    2006-01-01

    Multi-modal interfaces can support the integration of humans with information processing systems and computational devices to maximize the unique qualities that comprise a complex system. In a dynamic environment, such as a nuclear power plant control room, multi-modal interfaces, if designed correctly, can provide complementary interaction between the human operator and the system which can improve overall performance while reducing human error. Developing such interfaces can be difficult for a designer without explicit knowledge of Human Factors Engineering principles. The Multi-modal Interface Design Advisor (MIDA) was developed as a support tool for system designers and developers. It provides design recommendations based upon a combination of Human Factors principles, a knowledge base of historical research, and current interface technologies. MIDA's primary objective is to optimize available multi-modal technologies within a human computer interface in order to balance operator workload with efficient operator performance. The purpose of this paper is to demonstrate MIDA and illustrate its value as a design evaluation tool within the nuclear power industry. (authors)

  9. Compass cues used by a nocturnal bull ant, Myrmecia midas.

    Science.gov (United States)

    Freas, Cody A; Narendra, Ajay; Cheng, Ken

    2017-05-01

    Ants use both terrestrial landmarks and celestial cues to navigate to and from their nest location. These cues persist even as light levels drop during the twilight/night. Here, we determined the compass cues used by a nocturnal bull ant, Myrmecia midas , in which the majority of individuals begin foraging during the evening twilight period. Myrmecia midas foragers with vectors of ≤5   m when displaced to unfamiliar locations did not follow the home vector, but instead showed random heading directions. Foragers with larger home vectors (≥10   m) oriented towards the fictive nest, indicating a possible increase in cue strength with vector length. When the ants were displaced locally to create a conflict between the home direction indicated by the path integrator and terrestrial landmarks, foragers oriented using landmark information exclusively and ignored any accumulated home vector regardless of vector length. When the visual landmarks at the local displacement site were blocked, foragers were unable to orient to the nest direction and their heading directions were randomly distributed. Myrmecia midas ants typically nest at the base of the tree and some individuals forage on the same tree. Foragers collected on the nest tree during evening twilight were unable to orient towards the nest after small lateral displacements away from the nest. This suggests the possibility of high tree fidelity and an inability to extrapolate landmark compass cues from information collected on the tree and at the nest site to close displacement sites. © 2017. Published by The Company of Biologists Ltd.

  10. Transcriptomics of morphological color change in polychromatic Midas cichlids.

    Science.gov (United States)

    Henning, Frederico; Jones, Julia C; Franchini, Paolo; Meyer, Axel

    2013-03-13

    Animal pigmentation has received much attention in evolutionary biology research due to its strong implications for adaptation and speciation. However, apart from a few cases the genetic changes associated with these evolutionary processes remain largely unknown. The Midas cichlid fish from Central America are an ideal model system for investigating pigmentation traits that may also play a role in speciation. Most Midas cichlids maintain their melanophores and exhibit a grayish (normal) color pattern throughout their lives. A minority of individuals, however, undergo color change and exhibit a distinctive gold or even white coloration in adulthood. The ontogenetic color change in the Midas cichlids may also shed light on the molecular mechanisms underlying pigmentation disorders in humans. Here we use next-generation sequencing (Illumina) RNAseq analyses to compare skin transcriptome-wide expression levels in three distinct stages of color transformation in Midas cichlids. cDNA libraries of scale tissue, for six biological replicates of each group, were generated and sequenced using Illumina technology. Using a combination of three differential expression (DE) analyses we identified 46 candidate genes that showed DE between the color morphs. We find evidence for two key DE patterns: a) genes involved in melanosomal pathways are up-regulated in normally pigmented fish; and b) immediate early and inflammatory response genes were up-regulated in transitional fish, a response that parallels some human skin disorders such as melanoma formation and psoriasis. One of the DE genes segregates with the gold phenotype in a genetic cross and might be associated with incipient speciation in this highly "species-rich" lineage of cichlids. Using transcriptomic analyses we successfully identified key expression differences between different color morphs of Midas cichlid fish. These differentially expressed genes have important implications for our understanding of the molecular

  11. MIDAS: a database-searching algorithm for metabolite identification in metabolomics.

    Science.gov (United States)

    Wang, Yingfeng; Kora, Guruprasad; Bowen, Benjamin P; Pan, Chongle

    2014-10-07

    A database searching approach can be used for metabolite identification in metabolomics by matching measured tandem mass spectra (MS/MS) against the predicted fragments of metabolites in a database. Here, we present the open-source MIDAS algorithm (Metabolite Identification via Database Searching). To evaluate a metabolite-spectrum match (MSM), MIDAS first enumerates possible fragments from a metabolite by systematic bond dissociation, then calculates the plausibility of the fragments based on their fragmentation pathways, and finally scores the MSM to assess how well the experimental MS/MS spectrum from collision-induced dissociation (CID) is explained by the metabolite's predicted CID MS/MS spectrum. MIDAS was designed to search high-resolution tandem mass spectra acquired on time-of-flight or Orbitrap mass spectrometer against a metabolite database in an automated and high-throughput manner. The accuracy of metabolite identification by MIDAS was benchmarked using four sets of standard tandem mass spectra from MassBank. On average, for 77% of original spectra and 84% of composite spectra, MIDAS correctly ranked the true compounds as the first MSMs out of all MetaCyc metabolites as decoys. MIDAS correctly identified 46% more original spectra and 59% more composite spectra at the first MSMs than an existing database-searching algorithm, MetFrag. MIDAS was showcased by searching a published real-world measurement of a metabolome from Synechococcus sp. PCC 7002 against the MetaCyc metabolite database. MIDAS identified many metabolites missed in the previous study. MIDAS identifications should be considered only as candidate metabolites, which need to be confirmed using standard compounds. To facilitate manual validation, MIDAS provides annotated spectra for MSMs and labels observed mass spectral peaks with predicted fragments. The database searching and manual validation can be performed online at http://midas.omicsbio.org.

  12. A preliminary psychometric evaluation of Music in Dementia Assessment Scales (MiDAS).

    Science.gov (United States)

    McDermott, Orii; Orgeta, Vasiliki; Ridder, Hanne Mette; Orrell, Martin

    2014-06-01

    Music in Dementia Assessment Scales (MiDAS), an observational outcome measure for music therapy with people with moderate to severe dementia, was developed from qualitative data of focus groups and interviews. Expert and peer consultations were conducted at each stage of the scale development to maximize its content validity. This study aimed to evaluate the psychometric properties of MiDAS. Care home residents with dementia attended weekly group music therapy for up to ten sessions. Music therapists and care home staff were requested to complete weekly MiDAS ratings. The Quality of Life Scale (QoL-AD) was completed at three time-points. A total of 629 (staff = 306, therapist = 323) MiDAS forms were completed. The statistical analysis revealed that MiDAS has high therapist inter-rater reliability, low staff inter-rater reliability, adequate staff test-retest reliability, adequate concurrent validity, and good construct validity. High factor loadings between the five MiDAS Visual Analogue Scale (VAS) items, levels of Interest, Response, Initiation, Involvement, and Enjoyment, were found. This study indicates that MiDAS has good psychometric properties despite the small sample size. Future research with a larger sample size could provide a more in-depth psychometric evaluation, including further exploration of the underlying factors. MiDAS provides a measure of engagement with musical experience and offers insight into who is likely to benefit on other outcomes such as quality of life or reduction in psychiatric symptoms.

  13. Beyond topography - enhanced imaging of cometary dust with the MIDAS AFM

    Science.gov (United States)

    Bentley, M. S.; Torkar, K.; Jeszenszky, H.; Romstedt, J.

    2013-09-01

    The MIDAS atomic force microscope (AFM) onboard the Rosetta spacecraft is primarily designed to return the 3D shape and structure of cometary dust particles collected at comet 67P/Churyumov-Gerasimenko [1]. Commercial AFMs have, however, been further developed to measure many other sample properties. The possibilities to make such measurements with MIDAS are explored here.

  14. Kui õppimine ei edene / Tiia Lister

    Index Scriptorium Estoniae

    Lister, Tiia

    2006-01-01

    Soome Instituudis toimus 27. veebruaril õppepäev "Kui õppimine ei edene", et tutvustada, kuidas Soomes on nii riiklikul kui ka koolisisesel tasandil liigutud õpilasele kõige sobivama ja kasulikuma abistamisvormi otsingul

  15. The European Southern Observatory-MIDAS table file system

    Science.gov (United States)

    Peron, M.; Grosbol, P.

    1992-01-01

    The new and substantially upgraded version of the Table File System in MIDAS is presented as a scientific database system. MIDAS applications for performing database operations on tables are discussed, for instance, the exchange of the data to and from the TFS, the selection of objects, the uncertainty joins across tables, and the graphical representation of data. This upgraded version of the TFS is a full implementation of the binary table extension of the FITS format; in addition, it also supports arrays of strings. Different storage strategies for optimal access of very large data sets are implemented and are addressed in detail. As a simple relational database, the TFS may be used for the management of personal data files. This opens the way to intelligent pipeline processing of large amounts of data. One of the key features of the Table File System is to provide also an extensive set of tools for the analysis of the final results of a reduction process. Column operations using standard and special mathematical functions as well as statistical distributions can be carried out; commands for linear regression and model fitting using nonlinear least square methods and user-defined functions are available. Finally, statistical tests of hypothesis and multivariate methods can also operate on tables.

  16. A restructuring of CF package for MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S. H.; Kim, K. R.; Kim, D. H.; Cho, S. W.

    2004-01-01

    CF package, which evaluates user-specified 'control functions' and applies them to define or control various aspects of computation, has been restructured for the MIDAS computer code. MIDAS is being developed as an integrated severe accident analysis code with a user-friendly graphical user interface and modernized data structure. To do this, data transferring methods of current MELCOR code are modified and adopted into the CF package. The data structure of the current MELCOR code using FORTRAN77 causes a difficult grasping of meaning of the variables as well as waste of memory, difficulty is more over because its data is location information of other package's data due to characteristics of CF package. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type, which lead to an efficient memory treatment and an easy understanding of the code. Restructuring of the CF package addressed in this paper includes module development, subroutine modification, and treats MELGEN, which generates data file, as well as MELCOR, which is processing a calculation. The verification has been done by comparing the results of the modified code with those from the existing code. As the trends are similar to each other, it hints that the same approach could be extended to the entire code package. It is expected that code restructuring will accelerate the code domestication thanks to direct understanding of each variable and easy implementation of modified or newly developed models

  17. A restructuring of RN1 package for MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S. H.; Kim, D. H.; Kim, K. R.

    2003-01-01

    RN1 package, which is one of two fission product-related packages in MELCOR, has been restructured for the MIDAS computer code. MIDAS is being developed as an integrated severe accident analysis code with a user-friendly graphical user interface and modernized data structure. To do this, data transferring methods of current MELCOR code are modified and adopted into the RN1 package. The data structure of the current MELCOR code using FORTRAN77 causes a difficult grasping of meaning of the variables as well as waste of memory. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type, which lead to an efficient memory treatment and an easy understanding of the code. Restructuring of the RN1 package addressed in this paper includes module development, subroutine modification, and treats MELGEN, which generates data file, as well as MELCOR, which is processing a calculation. The verification has been done by comparing the results of the modified code with those from the existing code. As the trends are similar to each other, it hints that the same approach could be extended to the entire code package. It is expected that code restructuring will accelerate the code domestication thanks to direct understanding of each variable and easy implementation of modified or newly developed models

  18. MIDAS: Lessons learned from the first spaceborne atomic force microscope

    Science.gov (United States)

    Bentley, Mark Stephen; Arends, Herman; Butler, Bart; Gavira, Jose; Jeszenszky, Harald; Mannel, Thurid; Romstedt, Jens; Schmied, Roland; Torkar, Klaus

    2016-08-01

    The Micro-Imaging Dust Analysis System (MIDAS) atomic force microscope (AFM) onboard the Rosetta orbiter was the first such instrument launched into space in 2004. Designed only a few years after the technique was invented, MIDAS is currently orbiting comet 67P Churyumov-Gerasimenko and producing the highest resolution 3D images of cometary dust ever made in situ. After more than a year of continuous operation much experience has been gained with this novel instrument. Coupled with operations of the Flight Spare and advances in terrestrial AFM a set of "lessons learned" has been produced, cumulating in recommendations for future spaceborne atomic force microscopes. The majority of the design could be reused as-is, or with incremental upgrades to include more modern components (e.g. the processor). Key additional recommendations are to incorporate an optical microscope to aid the search for particles and image registration, to include a variety of cantilevers (with different spring constants) and a variety of tip geometries.

  19. A restructuring of COR package for MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S.H.; Kim, K.R.; Kim, D.H.

    2004-01-01

    The COR package, which calculates the thermal response of the core and the lower plenum internal structures and models the relocation of the core and lower plenum structural materials, has been restructured for the MIDAS computer code. MIDAS is being developed as an integrated severe accident analysis code with a user-friendly graphical user interface and a modernized data structure. To do this, the data transferring methods of the current MELCOR code are modified and adopted into the COR package. The data structure of the current MELCOR code using FORTRAN77 has a difficulty in grasping the meaning of the variables as well as a waste of memory. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type, which leads to an efficient memory treatment and an easy understanding of the code. Restructuring of the COR package addressed in this paper includes a module development, subroutine modification. The verification has been done by comparing the results of the modified code with those of the existing code. As the trends are similar to each other, it implies that the same approach could be extended to the entire code package. It is expected that the code restructuring will accelerated the code's domestication thanks to a direct understanding of each variable and an easy implementation of the modified or newly developed models. (author)

  20. A restructuring of RN2 package for MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S. H.; Kim, D. H.

    2003-01-01

    RN2 package, which is one of two fission product-related package in MELCOR, has been restructured for the MIDAS computer code. MIDAS is being developed as an integrated severe accident analysis code with a user-friendly graphical user interface and data structure. To do this, data transferring methods of current MELCOR code are modified and adopted into the RN2 package. The data structure of the current MELCOR code using FORTRAN77 causes a difficult grasping of meaning of the variables as well as waste of memory. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type, which lead to an efficient memory treatment and an easy understanding of the code. Restructuring of the RN2 package addressed in this paper includes module development, subroutine modification, and treats MELGEN, which generates data file, as well as MELCOR, which is processing a calculation. The validation has been done by comparing the results of the modified code with those from the existing code. As the trends are the similar to each other, it hints that the same approach could be extended to the entire code package. It is expected that code restructuring will accelerate the code domestication thanks to direct understanding of each variable and easy implementation of modified or newly developed models

  1. Reliability and Validity of the Greek Migraine Disability Assessment (MIDAS) Questionnaire.

    Science.gov (United States)

    Oikonomidi, Theodora; Vikelis, Michail; Artemiadis, Artemios; Chrousos, George P; Darviri, Christina

    2018-03-01

    The Migraine Disability Assessment (MIDAS) Questionnaire is a reliable and valid instrument for migraine-related disability. Such a tool is needed to quantify migraine-related disability in the Greek population. This validation study aims to assess the test-retest reliability, internal consistency, item discriminant and convergent validity of the Greek translation of the MIDAS. Adults diagnosed with migraine completed the MIDAS Questionnaire on two occasions 3 weeks apart to assess reliability, and completed the RAND-36 to assess validity. Participants (n = 152) had a median MIDAS score of 24 and mostly severe disability (58% were grade IV). The test-retest reliability analysis (N = 59) revealed excellent reliability for the total score. Internal consistency was α = 0.71 for initial and α = 0.82 for retest completion. For item discriminant validity, the correlations between each question and the total score were significant, with high correlations for questions 2-5 (range 0.67 ≤ r ≤ 0.79; p MIDAS score tended to have better wellbeing. Psychometric properties are comparable with those of other published validation studies of the MIDAS and the original. Findings on question 1 show that missing work/school days may be closely related with increased affect issues. The Greek version of the MIDAS Questionnaire has good reliability and validity. This study allowed for cross-cultural comparability of research findings.

  2. Reliability and validity of migraine disability assessment questionnaire-Thai version (Thai-MIDAS).

    Science.gov (United States)

    Seethong, Piman; Nimmannit, Akarin; Chaisewikul, Rungsan; Prayoonwiwat, Naraporn; Chotinaiwattarakul, Wattanachai

    2013-02-01

    To assess the validity and test-retest reliability of a Thai translation of the Migraine Disability Assessment (MIDAS) Questionnaire in Thai patients with migraine. Migraineurs from the Headache Clinic in Siriraj Hospital were recruited and asked to complete a 13-weeks diary and answered the Thai-MIDAS at once. Some participants were asked to provide the 2nd Thai-MIDAS in the next 2 weeks for test-retest reliability. Ninety-three patients had completed the 13-weeks diaries. Age range was 18-58 years with mean 37.69 +/- 9.60 years. All 5 items and the total score of Thai-MIDAS were moderately correlated with data from 13-weeks diary (Spearman's correlation coefficient = 0.32-0.62). The test-retest reliability of the total score of Thai-MIDAS in 30 patients demonstrated a highly reliable degree of intraclass correlation (ICC = 0.76, 95% CI 0.49-0.88). The present study reveals that the Thai-MIDAS has satisfactory validity and reliability in comparison with the original English MIDAS version.

  3. Accuracy Potential and Applications of MIDAS Aerial Oblique Camera System

    Science.gov (United States)

    Madani, M.

    2012-07-01

    Airborne oblique cameras such as Fairchild T-3A were initially used for military reconnaissance in 30s. A modern professional digital oblique camera such as MIDAS (Multi-camera Integrated Digital Acquisition System) is used to generate lifelike three dimensional to the users for visualizations, GIS applications, architectural modeling, city modeling, games, simulators, etc. Oblique imagery provide the best vantage for accessing and reviewing changes to the local government tax base, property valuation assessment, buying & selling of residential/commercial for better decisions in a more timely manner. Oblique imagery is also used for infrastructure monitoring making sure safe operations of transportation, utilities, and facilities. Sanborn Mapping Company acquired one MIDAS from TrackAir in 2011. This system consists of four tilted (45 degrees) cameras and one vertical camera connected to a dedicated data acquisition computer system. The 5 digital cameras are based on the Canon EOS 1DS Mark3 with Zeiss lenses. The CCD size is 5,616 by 3,744 (21 MPixels) with the pixel size of 6.4 microns. Multiple flights using different camera configurations (nadir/oblique (28 mm/50 mm) and (50 mm/50 mm)) were flown over downtown Colorado Springs, Colorado. Boresight fights for 28 mm nadir camera were flown at 600 m and 1,200 m and for 50 mm nadir camera at 750 m and 1500 m. Cameras were calibrated by using a 3D cage and multiple convergent images utilizing Australis model. In this paper, the MIDAS system is described, a number of real data sets collected during the aforementioned flights are presented together with their associated flight configurations, data processing workflow, system calibration and quality control workflows are highlighted and the achievable accuracy is presented in some detail. This study revealed that the expected accuracy of about 1 to 1.5 GSD (Ground Sample Distance) for planimetry and about 2 to 2.5 GSD for vertical can be achieved. Remaining systematic

  4. ACCURACY POTENTIAL AND APPLICATIONS OF MIDAS AERIAL OBLIQUE CAMERA SYSTEM

    Directory of Open Access Journals (Sweden)

    M. Madani

    2012-07-01

    Full Text Available Airborne oblique cameras such as Fairchild T-3A were initially used for military reconnaissance in 30s. A modern professional digital oblique camera such as MIDAS (Multi-camera Integrated Digital Acquisition System is used to generate lifelike three dimensional to the users for visualizations, GIS applications, architectural modeling, city modeling, games, simulators, etc. Oblique imagery provide the best vantage for accessing and reviewing changes to the local government tax base, property valuation assessment, buying & selling of residential/commercial for better decisions in a more timely manner. Oblique imagery is also used for infrastructure monitoring making sure safe operations of transportation, utilities, and facilities. Sanborn Mapping Company acquired one MIDAS from TrackAir in 2011. This system consists of four tilted (45 degrees cameras and one vertical camera connected to a dedicated data acquisition computer system. The 5 digital cameras are based on the Canon EOS 1DS Mark3 with Zeiss lenses. The CCD size is 5,616 by 3,744 (21 MPixels with the pixel size of 6.4 microns. Multiple flights using different camera configurations (nadir/oblique (28 mm/50 mm and (50 mm/50 mm were flown over downtown Colorado Springs, Colorado. Boresight fights for 28 mm nadir camera were flown at 600 m and 1,200 m and for 50 mm nadir camera at 750 m and 1500 m. Cameras were calibrated by using a 3D cage and multiple convergent images utilizing Australis model. In this paper, the MIDAS system is described, a number of real data sets collected during the aforementioned flights are presented together with their associated flight configurations, data processing workflow, system calibration and quality control workflows are highlighted and the achievable accuracy is presented in some detail. This study revealed that the expected accuracy of about 1 to 1.5 GSD (Ground Sample Distance for planimetry and about 2 to 2.5 GSD for vertical can be achieved. Remaining

  5. "Kurgibakter" ei tulnudki importkurgiga? / Kaivo Kopli

    Index Scriptorium Estoniae

    Kopli, Kaivo

    2011-01-01

    Nakkuspuhang Saksamaal ei pruugi olla põhjustatud Hispaaniast toodud kurkidest. Mitmed riigid on peatanud kurkide ja mõnede muude köögiviljade impordi Hispaaniast, Hispaania tahab nõuda Euroopa Komijonilt kompensatsiooni müümata jäänud köögiviljade eest

  6. Hispaania ei usu ETA rahupakkumisse / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2004-01-01

    Baski terrorirühmitus kutsus uut peaministrit Jose Luis Rodriguez Zapaterot dialoogile, hiljuti valimised võitnud Sotsialistlik Töölispartei teatas vastuseks, et ETA on terroristlik rühmitus ja selle avaldustele tähelepanu ei osutata. Vt. samas: Vaherahule järgnes terrorilaine

  7. Euroopa põllumehed ei taha muutusi

    Index Scriptorium Estoniae

    2008-01-01

    Euroopa põllumajandusühistuid koondava ühenduse COGECA ja Euroopa põllumeeste suurima esindusorganisatsiooni COPA seisukoht on, et praegu ei ole õige aeg võtta Euroopa põllumehelt tootmiseks ette nähtud toetust ning suunata see ümber maaelu arenguks

  8. Challenges and Possibilities of EIS on PEMEC

    DEFF Research Database (Denmark)

    Elsøe, Katrine; Kraglund, Mikkel Rykær; Hjelm, Johan

    2017-01-01

    Electrochemical impedance spectroscopy (EIS) has been proven a very strong electrochemical characterization tool in electrochemical research in general and in the areas of fuel cell and battery research in particular. However, this is not the case for polymer electrolyte membrane electrolysis cells...

  9. Ekskantslerit ei kollita huvide konflikt / Nils Niitra

    Index Scriptorium Estoniae

    Niitra, Nils, 1975-

    2010-01-01

    Kaitseministeeriumi vastuse kohaselt vaatasid sealsed audiitorid üle teadus-arendustegevususe uurimistoetuste maksmise ja seni sõlmitud lepingud ning selgus, et kahtlustused, nagu oleks kaitseministeeriumi endine kantsler Lauri Almann oma eraäri juba kantslerina ette valmistanud, ei vasta tõele. Autor vabandab Lauri Almanni ees

  10. Kes ei maga, see vaatab / Jaanus Kulli

    Index Scriptorium Estoniae

    Kulli, Jaanus, 1955-

    2004-01-01

    Peale mängufilmi "Täna öösel me ei maga" esilinastust Coca-Cola Plazas : režissöör Ilmar Taska : produtsent ning üks stsenariste Kristian Taska. Lisaks vastavad Signe Kivi ja Urmas Paet küsimusele "Millised on teie esmamuljed filmist?"

  11. Tallinna Ülikool ei kiida riiki

    Index Scriptorium Estoniae

    2006-01-01

    Tallinna Ülikool teatas läbi kõneisiku, et juhtkonna otsusel ei laulda tänasel avaaktusel, kus osalevad keskerakondlased, üliõpilashümni "Gaudeamus" neljandat salmi - "Elagu vabariik ja need, kes teda juhivad"

  12. E-I 90. Proceedings. V. 2

    International Nuclear Information System (INIS)

    1990-01-01

    The developments and technology trends taking place in the power industry in South Africa were examined at the E-I 90 conference. Some of the developments in local nuclear power technology were also discussed. Separate abstracts were prepared for five of the papers presented at the conference. The remaining papers were considered outside the subject scope of INIS

  13. Madal palk ei ole konkurentsieelis / Kristo Kiviorg

    Index Scriptorium Estoniae

    Kiviorg, Kristo

    2007-01-01

    Seminaril "Peidetud väärtus: kuidas ettevõtted saavutavad tavaliste inimeste abiga erakordseid tulemusi" ettekannetega esinenud Stanfordi Ülikooli professor Jeffrey Pfeffer ning inimressursside juhtimise konsultant David Russo tõdesid, et madal palk ei taga firmadele konkurentsieelist, kuigi paljud juhid nõnda arvavad

  14. Vale, mis ei taha surra / Urmas Kiil

    Index Scriptorium Estoniae

    Kiil, Urmas

    2005-01-01

    Juuditar Hadassa Ben-Itto raamatu "Vale, mis ei taha surra" (The Lie That Wouldn't Die: the Protocols of the Elders of Zion) sünniloost. Autor, kes oli Iisraelis kõrge kohtunik, loobus oma karjäärist, et tuua avalikkuse ette tõde XX sajandil palju surma külvanud plagiaadist "Siioni tarkade protokollid"

  15. A revision of the Anthaxia (Anthaxia) midas Kiesenwetter, 1857 species-group (Coleoptera: Buprestidae: Anthaxiini).

    Science.gov (United States)

    Baiocchi, Daniele; Magnani, Gianluca

    2018-01-10

    The Anthaxia (Anthaxia) midas Kiesenwetter, 1857 species-group is defined and revised. A new species from Turkey, A. (A.) cebecii sp. nov., is described and compared to its most similar species. A. midas oberthuri Schaefer, 1938 is elevated to the rank of species, and a lectotype is designated. A. (A.) spathuligera Obenberger, 1924 and A. (A.) midas muelleri Obenberger, 1925 are reconfirmed synonyms of A. midas Kiesenwetter, 1857.All species of the new species-group are illustrated, including the hitherto unknown male of A. (A.) patsyae Baiocchi, 2008, all type specimens and original data labels. In addition to diagnostic characters, informations on the distribution, biology and taxonomic position of each species are also presented, together with a short definition of the new species-group, and a key to its species.

  16. Utilizing a multiprocessor architecture - The performance of MIDAS

    International Nuclear Information System (INIS)

    Maples, C.; Logan, D.; Meng, J.; Rathbun, W.; Weaver, D.

    1983-01-01

    The MIDAS architecture organizes multiple CPUs into clusters called distributed subsystems. Each subsystem consists of an array of processors controlled by a supervisory CPU. The multiprocessor array is composed of commercial CPUs (with floating point hardware) and specialized processing elements. Interprocessor communication within the array may occur either through switched memory modules or common shared memory. The architecture permits multiple processors to be focused on single problems. A distributed subsystem has been constructed and tested. It currently consists of a supervisor CPU; 16 blocks of independently switchable memory; 9 general purpose, VAX-class CPUs; and 2 specialized pipelined processors to handle I/O. Results on a variety of problems indicate that the subsystem performs 8 to 15 times faster than a standard computer with an identical CPU. The difference in performance represents the effect of differing CPU and I/O requirements

  17. Responsiveness of migraine-ACT and MIDAS questionnaires for assessing migraine therapy.

    Science.gov (United States)

    García, María Luisa; Baos, Vicente; Láinez, Miguel; Pascual, Julio; López-Gil, Arturo

    2008-10-01

    Migraine is frequently undertreated. The 4-item Migraine Assessment of Current Therapy (Migraine-ACT) questionnaire is a simple and reliable tool to identify patients requiring a change in current acute migraine treatment. To investigate the responsiveness of the Migraine-ACT tool, and compare it with that of the Migraine Disability Assessment (MIDAS) questionnaire, for patients with migraine at 1100 primary care sites in Spain. Patients eligible for this open-label, 2-visit prospective study reported migraine for >1 year and >or=1 migraine attack per month and were new to the clinic or on follow-up care for MIDAS questionnaires were administered, and patient satisfaction with treatment was recorded, at baseline and at 3 months. A total of 3272 patients, 78% female, were enrolled, and 2877 (88%) returned for the 3-month visit. Investigators changed baseline migraine treatment for 72% of returning patients; 85% and 80% of these patients had improved Migraine-ACT and MIDAS scores at 3 months, respectively. Patients who reported being completely or very satisfied with migraine treatment numbered 492 (15%) at baseline and 1406 (49%) at 3 months. Migraine-ACT and MIDAS score agreement for improvement at 3 months was poor (kappa = 0.339). Both the mean MIDAS score and the distribution of Migraine-ACT scores improved over the course of 3 months; however, Migraine-ACT scores were significantly (P MIDAS scores. The area under the curve in the receiver-operating characteristic analysis was significantly (P MIDAS (0.70) questionnaire. These results suggest that the Migraine-ACT questionnaire can be used more reliably than the MIDAS questionnaire for detecting improvements in treatment of new and follow-up patients with migraine.

  18. [The psychometric properties of the Turkish version of Myocardial Infarction Dimensional Assessment Scale (MIDAS)].

    Science.gov (United States)

    Yılmaz, Emel; Eser, Erhan; Şekuri, Cevad; Kültürsay, Hakan

    2011-08-01

    The purpose of this study was to describe the psychometric properties of the Myocardial Infarction Dimensional Assessment Scale (MIDAS). This is a methodological cultural adaptation study. The MIDAS consists of 35-items covering seven domains: physical activity, insecurity, emotional reaction, dependency, diet, concerns over medication, and side effects which are rated on a five-point Likert scale from 1: never to 5:always. The highest score of MIDAS is 100.Quality of life (QOL) decreases as the score of scale increases. Overall 185 myocardial infarction (MI) patients were enrolled in this study. Cronbach alpha was used for the reliability analysis. The criterion validity, structural validity, and sensitivity analysis approach was used for validity analysis. New York Heart Association (NYHA) and the Canadian Cardiovascular Society Functional Classifications (CCSFC) for testing the criterion validity; SF-36 for construct validity testing of the Turkish version of the MIDAS were used. The range of Cronbach alpha values is 0.79-0.90 for seven domains of the scale. No problematic items were observed for the entire scale. Medication related domains of the MIDAS showed considerable floor effects (35.7%-22.7%). Confirmatory Factor analysis indicators [Comparative Fit Index (CFI) =0.95 and Root Mean Square Error of Approximation (RMSEA) =0.075] supported the construct validity of MIDAS. Convergent validity of the MIDAS was confirmed with correlation of SF-36 scale where appropriate. Criterion validity results was also satisfactory by comparing different stages of the NYHA and the CCSFC (pMIDAS is a reliable and valid instrument.

  19. Cometary dust at the nanometre scale - the MIDAS view after perihelion

    Science.gov (United States)

    Bentley, M. S.; Torkar, K.; Jeszenszky, H.; Romstedt, J.; Schmied, R.; Mannel, T.

    2015-10-01

    The MIDAS instrument on-board the Rosetta orbiter [1] is a unique combination of a dust collection and handling system and a high resolution Atomic Force Microscope (AFM). By building three-dimensional images of the dust particle topography with nano- to micrometre resolution, MIDAS addresses a range of fundamental questions in Solar System and cometary sciences. The greatest number of particles is expected to be collected around perihelion and the initial results of imaging these will be presented.

  20. Ionospheric tomography over South Africa: Comparison of MIDAS and ionosondes measurements

    Science.gov (United States)

    Giday, Nigussie M.; Katamzi, Zama T.; McKinnell, Lee-Anne

    2016-01-01

    This paper aims to show the results of an ionospheric tomography algorithm called Multi-Instrument Data Analysis System (MIDAS) over the South African region. Recorded data from a network of 49-53 Global Positioning System (GPS) receivers over the South African region was used as input for the inversion. The inversion was made for April, July, October and December representing the four distinct seasons (Autumn, Winter, Spring and Summer respectively) of the year 2012. MIDAS reconstructions were validated by comparing maximum electron density of the F2 layer (NmF2) and peak height (hmF2) values predicted by MIDAS to those derived from three South African ionosonde measurements. The diurnal and seasonal trends of the MIDAS NmF2 values were in good agreement with the respective NmF2 values derived from the ionosondes. In addition, good agreement was found between the two measurements with minimum and maximum coefficients of determination (r2) between 0.84 and 0.96 in all the stations and validation days. The seasonal trend of the NmF2 values over the South Africa region has been reproduced using this inversion which was in good agreement with the ionosonde measurements. Moreover, a comparison of the International Reference Ionosphere (IRI-2012) model NmF2 values with the respective ionosonde derived NmF2 values showed to have higher deviation than a similar comparison between the MIDAS reconstruction and the ionosonde measurements. However, the monthly averaged hmF2 values derived from IRI 2012 model showed better agreement than the respective MIDAS reconstructed hmF2 values compared with the ionosonde derived hmF2 values.The performance of the MIDAS reconstruction was observed to deteriorate with increased geomagnetic conditions. MIDAS reconstructed electron density were slightly elevated during three storm periods studied (24 April, 15 July and 8 October) which was in good agreement with the ionosonde measurements.

  1. Microbleed detection using automated segmentation (MIDAS): a new method applicable to standard clinical MR images.

    Science.gov (United States)

    Seghier, Mohamed L; Kolanko, Magdalena A; Leff, Alexander P; Jäger, Hans R; Gregoire, Simone M; Werring, David J

    2011-03-23

    Cerebral microbleeds, visible on gradient-recalled echo (GRE) T2* MRI, have generated increasing interest as an imaging marker of small vessel diseases, with relevance for intracerebral bleeding risk or brain dysfunction. Manual rating methods have limited reliability and are time-consuming. We developed a new method for microbleed detection using automated segmentation (MIDAS) and compared it with a validated visual rating system. In thirty consecutive stroke service patients, standard GRE T2* images were acquired and manually rated for microbleeds by a trained observer. After spatially normalizing each patient's GRE T2* images into a standard stereotaxic space, the automated microbleed detection algorithm (MIDAS) identified cerebral microbleeds by explicitly incorporating an "extra" tissue class for abnormal voxels within a unified segmentation-normalization model. The agreement between manual and automated methods was assessed using the intraclass correlation coefficient (ICC) and Kappa statistic. We found that MIDAS had generally moderate to good agreement with the manual reference method for the presence of lobar microbleeds (Kappa = 0.43, improved to 0.65 after manual exclusion of obvious artefacts). Agreement for the number of microbleeds was very good for lobar regions: (ICC = 0.71, improved to ICC = 0.87). MIDAS successfully detected all patients with multiple (≥2) lobar microbleeds. MIDAS can identify microbleeds on standard MR datasets, and with an additional rapid editing step shows good agreement with a validated visual rating system. MIDAS may be useful in screening for multiple lobar microbleeds.

  2. Aluminum (III) and gallium (III) complexes with methyliminodiacetic acid: Crystal structures of Cat[M(Mida)2] (Cat+=Na, K, NH4; M3+=Al, Ga) and Me4N[Ga(Mida)2]·H2O

    International Nuclear Information System (INIS)

    Ilyukhin, A.B.; Petrosyants, S.P.; Milovanov, S.V.; Malyarik, M.A.

    1997-01-01

    The bis chelate complexes Cat[M(Mida) 2 ] and Me 4 N[Ga(Mida) 2 ]·H 2 O are synthesized from aqueous solutions M(NO 3 ) 3 -2H 2 Mida-CatOH (M 3+ =Al, Ga; Cat + =Na, K, NH 4 ) and Ga(OH) 3 -2H 2 Mida-Me 4 NOH. The crystal structures of the isostructural compounds Cat[M(Mida) 2 ] (Cat=Na, M=Al; Cat=K, M=Al; Cat=Na, M=Ga) and Me 4 N[Ga(Mida) 2 ]·H 2 O are determined by X-ray structure analysis. According to the X-ray powder diffraction analysis, all the six compounds Cat[M(Mida) 2 ] (Cat=Na, K, NH 4 ; M=Al, Ga) are isostructural. The octahedral anion in Cat[M(Mida) 2 ] and Me 4 N[Ga(Mida) 2 ]·H 2 O exhibits a trans(N)- fac configuration

  3. IT ei loe / Nicholas G. Carr

    Index Scriptorium Estoniae

    Carr, Nicholas G.

    2003-01-01

    Harvard Business Review endise toimetaja arvates on infotehnoloogia (IT) strateegiline tähtsus ettevõtetes oluliselt vähenenud ning innovaatilised IT lahendused ei anna enam konkurentsieeliseid, mille tõttu peab muutuma ka juhtide suhtumine IT riskidesse, investeeringutesse ja juhtimisse. Vt. samas: Kuidas vältida üleinvesteerimist IT-sse?; Liiga palju head; Mis saab müüjatest?; Uued reeglid IT juhtimises. Kommenteerivad Henn Sarv, Avo Kokk, Olli Heinonen ja Jüri Kaljundi

  4. Skype'i loojad : teeme, mida tahame! / interv. Kristjan Otsmann

    Index Scriptorium Estoniae

    2007-01-01

    Skype'i loojad Jaan Tallinn, Toivo Annust, Ahti Heinla ja Priit Kasesalu, kes on koondunud investeerimisfirmasse Ambient Sound Investments, ning firma tegevjuht Tauno Tats vastavad küsimustele, mis puudutavad nende raha investeerimist. A. Heinla sõnul ei ole nende investeerimise eesmärk teenida üha rohkem raha, sisuline eesmärk on investeerida tehnoloogiasse, edendada tehnoloogiat kogu maailmas. Kommenteerivad Allan Martinson ja Jüri Kaljundi

  5. Vallo Reimaa : Kavas ei ole mingit omavalitsuse reformi / Vallo Reimaa

    Index Scriptorium Estoniae

    Reimaa, Vallo

    2007-01-01

    Regionaalminister Vallo Reimaa vastab online-intervjuus küsimustele, mitu maakonda on Eestis nelja aasta pärast, mida ta arvab ideest kaotada regionaalministri koht, kas on reaalne vähendada nii omavalitsusi kui ka ametnike arvu

  6. Content Validity and Reliability of Multiple Intelligences Developmental Assessment Scales (MIDAS Translated into Persian

    Directory of Open Access Journals (Sweden)

    Mahnaz Saeidi

    2012-11-01

    Full Text Available This study aimed to translate MIDAS questionnaire from English into Persian and determine its content validity and reliability. MIDAS was translated and validated on a sample (N = 110 of Iranian adult population. The participants were both male and female with the age range of 17-57. They were at different educational levels and from different ethnic groups in Iran. A translating team, consisting of five members, bilingual in English and Persian and familiar with multiple intelligences (MI theory and practice, were involved in translating and determining content validity, which included the processes of forward translation, back-translation, review, final proof-reading, and testing. The statistical analyses of inter-scale correlation were performed using the Cronbach's alpha coefficient. In an intra-class correlation, the Cronbach's alpha was high for all of the questions. Translation and content validity of MIDAS questionnaire was completed by a proper process leading to high reliability and validity. The results suggest that Persian MIDAS (P-MIDAS could serve as a valid and reliable instrument for measuring Iranian adults MIs.

  7. The MIDAS telescope for microwave detection of ultra-high energy cosmic rays

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez-Muñiz, J. [Universidad de Santiago de Compostela, Departamento de Física de Partículas, Campus Sur, Universidad, E-15782 Santiago de Compostela (Spain); Amaral Soares, E. [Universidade Federal do Rio de Janeiro, Instituto de Física, Cidade Universitaria, Caixa Postal 68528, 21945-970 Rio de Janeiro, RJ (Brazil); Berlin, A.; Bogdan, M. [University of Chicago, Enrico Fermi Institute and Kavli Institute for Cosmological Physics, 5640 S. Ellis Ave., Chicago, IL 60637 (United States); Boháčová, M. [University of Chicago, Enrico Fermi Institute and Kavli Institute for Cosmological Physics, 5640 S. Ellis Ave., Chicago, IL 60637 (United States); Institute of Physics of the Academy of Sciences of the Czech Republic, Na Slovance 2, CZ-182 21 Praha 8 (Czech Republic); Bonifazi, C. [Universidade Federal do Rio de Janeiro, Instituto de Física, Cidade Universitaria, Caixa Postal 68528, 21945-970 Rio de Janeiro, RJ (Brazil); Carvalho, W.R. [Universidad de Santiago de Compostela, Departamento de Física de Partículas, Campus Sur, Universidad, E-15782 Santiago de Compostela (Spain); Mello Neto, J.R.T. de [Universidade Federal do Rio de Janeiro, Instituto de Física, Cidade Universitaria, Caixa Postal 68528, 21945-970 Rio de Janeiro, RJ (Brazil); Facal San Luis, P., E-mail: facal@kicp.uchicago.edu [University of Chicago, Enrico Fermi Institute and Kavli Institute for Cosmological Physics, 5640 S. Ellis Ave., Chicago, IL 60637 (United States); Genat, J.F.; Hollon, N.; Mills, E.; Monasor, M.; Privitera, P. [University of Chicago, Enrico Fermi Institute and Kavli Institute for Cosmological Physics, 5640 S. Ellis Ave., Chicago, IL 60637 (United States); and others

    2013-08-11

    We present the design, implementation and data taking performance of the MIcrowave Detection of Air Showers (MIDAS) experiment, a large field of view imaging telescope designed to detect microwave radiation from extensive air showers induced by ultra-high energy cosmic rays. This novel technique may bring a tenfold increase in detector duty cycle when compared to the standard fluorescence technique based on detection of ultraviolet photons. The MIDAS telescope consists of a 4.5 m diameter dish with a 53-pixel receiver camera, instrumented with feed horns operating in the commercial extended C-Band (3.4–4.2 GHz). A self-trigger capability is implemented in the digital electronics. The main objectives of this first prototype of the MIDAS telescope – to validate the telescope design, and to demonstrate a large detector duty cycle – were successfully accomplished in a dedicated data taking run at the University of Chicago campus prior to installation at the Pierre Auger Observatory. -- Highlights: • The MIDAS objective is to detect ultra high energy cosmic rays using microwaves. • GHz radiation could provide a powerful alternative to current detection methods. • The MIDAS prototype explores the potential of the microwave technique.

  8. The MIDAS telescope for microwave detection of ultra-high energy cosmic rays

    International Nuclear Information System (INIS)

    Alvarez-Muñiz, J.; Amaral Soares, E.; Berlin, A.; Bogdan, M.; Boháčová, M.; Bonifazi, C.; Carvalho, W.R.; Mello Neto, J.R.T. de; Facal San Luis, P.; Genat, J.F.; Hollon, N.; Mills, E.; Monasor, M.; Privitera, P.

    2013-01-01

    We present the design, implementation and data taking performance of the MIcrowave Detection of Air Showers (MIDAS) experiment, a large field of view imaging telescope designed to detect microwave radiation from extensive air showers induced by ultra-high energy cosmic rays. This novel technique may bring a tenfold increase in detector duty cycle when compared to the standard fluorescence technique based on detection of ultraviolet photons. The MIDAS telescope consists of a 4.5 m diameter dish with a 53-pixel receiver camera, instrumented with feed horns operating in the commercial extended C-Band (3.4–4.2 GHz). A self-trigger capability is implemented in the digital electronics. The main objectives of this first prototype of the MIDAS telescope – to validate the telescope design, and to demonstrate a large detector duty cycle – were successfully accomplished in a dedicated data taking run at the University of Chicago campus prior to installation at the Pierre Auger Observatory. -- Highlights: • The MIDAS objective is to detect ultra high energy cosmic rays using microwaves. • GHz radiation could provide a powerful alternative to current detection methods. • The MIDAS prototype explores the potential of the microwave technique

  9. Polarized light use in the nocturnal bull ant, Myrmecia midas.

    Science.gov (United States)

    Freas, Cody A; Narendra, Ajay; Lemesle, Corentin; Cheng, Ken

    2017-08-01

    Solitary foraging ants have a navigational toolkit, which includes the use of both terrestrial and celestial visual cues, allowing individuals to successfully pilot between food sources and their nest. One such celestial cue is the polarization pattern in the overhead sky. Here, we explore the use of polarized light during outbound and inbound journeys and with different home vectors in the nocturnal bull ant, Myrmecia midas . We tested foragers on both portions of the foraging trip by rotating the overhead polarization pattern by ±45°. Both outbound and inbound foragers responded to the polarized light change, but the extent to which they responded to the rotation varied. Outbound ants, both close to and further from the nest, compensated for the change in the overhead e-vector by about half of the manipulation, suggesting that outbound ants choose a compromise heading between the celestial and terrestrial compass cues. However, ants returning home compensated for the change in the e-vector by about half of the manipulation when the remaining home vector was short (1-2 m) and by more than half of the manipulation when the remaining vector was long (more than 4 m). We report these findings and discuss why weighting on polarization cues change in different contexts.

  10. A restructuring of TF package for MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S. H.; Song, Y. M.; Kim, D. H.

    2002-01-01

    TF package which defines some interpolation and extrapolation condition through user defined table has been restructured in MIDAS computer code. To do this, data transferring methods of current MELCOR code are modified and adopted into TF package. The data structure of the current MELCOR code using FORTRAN77 causes a difficult grasping of the meaning of the variables as well as waste of memory. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type, which lead to an efficient memory treatment and an easy understanding of the code. Restructuring of TF package addressed in this paper does module development and subroutine modification, and treats MELGEN which is making restart file as well as MELCOR which is processing calculation. The validation has been done by comparing the results of the modified code with those from the existing code, and it is confirmed that the results are the same. It hints that the similar approach could be extended to the entire code package. It is expected that code restructuring will accelerate the code domestication thanks to direct understanding of each variable and easy implementation of modified or newly developed models

  11. Topografia do cone medular do sauim (Saguinus midas Topography of the medullary cone in sauim (Saguinus midas

    Directory of Open Access Journals (Sweden)

    Danielli Martinelli Martins

    2013-06-01

    Full Text Available Primata endêmico do Brasil, especificamente da floresta Amazônica, o Sauim alimentam-se de pequenos vertebrados, invertebrados, exudatos, flores, néctar, folhas e fungos, cuja morfologia é pouco conhecida. Assim, objetivou-se estabelecer parâmetros morfométricos e topográficos do cone medular dessa espécie, que sirvam de base para a prática das anestesias epidurais. Para tanto, foram avaliados quatro exemplares, provenientes da Universidade Federal Rural da Amazônia (UFRA. O Saguinus midas apresentou sete vértebras lombares e três vértebras sacrais. Após a dissecação do cone medular, registrou-se os aspectos anatômicos de interesse, enfatizando seu início (base e seu término (ápice, que, após mensuração, revelou base em nível de L4 e ápice em S2, com comprimento médio de 5,38cm, o que leva a sugerir a região lombosacral como sendo a mais adequada para o desenvolvimento da prática de anestesias epidurais.Primate endemic to Brazil, specifically in the Amazon rainforest, the Sauim feed on small vertebrates, invertebrates, exudates, flowers, nectar, leaves and fungi whose morphology is poorly known. Thus, the objective was to establish morphometric parameters and topographical conus of this species, as a basis for the practice of epidural anesthesia. For this purpose, four samples were evaluated, from the Universidade Federal Rural da Amazônia (UFRA. The Saguinus midas had seven lumbar vertebrae and three sacral vertebrae. After dissection of the conus, we recorded the anatomy of interest, emphasizing its beginning (base and its end (apex, revealed that after measuring the level of base peak in L4 and S2, with an average length of 5.38cm, which leads us to suggest the lumbosacral region as the most suitable for the development of the practice of epidural anesthesia.

  12. Four EIS Perspectives: A literature review

    DEFF Research Database (Denmark)

    Pries-Heje, Jan; Svejvig, Per

    A literature review of the Enterprise Information Systems literature reveals a number of recurring issues. We identify and detail four different perspectives that together categorizes the topics found. The first being a technical-rational perspective. The second being a social perspective....... The third being a more political and emergent perspective. Fourth, we identify a design-oriented perspective. We categorize the literature on EIS using these four perspectives, and for each perspective we identify core issues. Finally we discuss how the four perspectives complement each other....

  13. EIS Response of MIC on Carbon Steel

    DEFF Research Database (Denmark)

    Hilbert, Lisbeth Rischel; Maahn, Ernst

    1998-01-01

    Abstract Microbially influenced corrosion of carbon steel under sulphate reducing (sulphide-producing) bacterial activity (SRB) results in the formation of both ferrous sulphides as well as biofilm on the metal surface. The electrochemical characteristics of the ferrous sulphide/steel interface...... as compared to the biofilm/ferrous sulphide/steel interface has been studied with EIS, DC polarisations (Tafel, LPR) and a potentiostatic step technique. The electrochemical response is related to a threshold sulphide concentration above which very characteristic changes such as indications of finite...

  14. A Multi-Cultural Comparison of the Factor Structure of the MIDAS for Adults/College Students.

    Science.gov (United States)

    Jones, James A.

    The Multiple Intelligences Developmental Assessment Scales (MIDAS) instrument was developed to measure eight constructs of intelligence. The 119-item MIDAS provides scores for 26 subscales in addition to the 8 major scales. Using the 26 subscales, a factor structure was developed on half of a U.S. sample of college students (n=834), while the…

  15. EI competencies as a related but different characteristic than intelligence

    Science.gov (United States)

    Boyatzis, Richard E.; Batista-Foguet, Joan M.; Fernández-i-Marín, Xavier; Truninger, Margarida

    2015-01-01

    Amid the swarm of debate about emotional intelligence (EI) among academics are claims that cognitive intelligence, or general mental ability (g), is a stronger predictor of life and work outcomes as well as the counter claims that EI is their strongest predictor. Nested within the tempest in a teapot are scientific questions as to what the relationship is between g and EI. Using a behavioral approach to EI, we examined the relationship of a parametric measure of g as the person’s GMAT scores and collected observations from others who live and work with the person as to the frequency of his or her EI behavior, as well as the person’s self-assessment. The results show that EI, as seen by others, is slightly related to g, especially for males with assessment from professional relations. Further, we found that cognitive competencies are more strongly related to GMAT than EI competencies. For observations from personal relationships or self-assessment, there is no relationship between EI and GMAT. Observations from professional relations reveal a positive relationship between cognitive competencies and GMAT and EI and GMAT for males, but a negative relationship between EI and GMAT for females. PMID:25713545

  16. MiDAS Field Guide – a Comprehensive Online Source of Information About the Microbes of Activated Sludge

    DEFF Research Database (Denmark)

    Nierychlo, Marta; McIlroy, Simon Jon; Saunders, Aaron Marc

    this information in MiDAS field guide (www.midasfieldguide.org). MiDAS taxonomy gives a solid foundation for the study of microbial ecology of the wastewater treatment processes. The online MiDAS field guide links the identity of genera that are important for the wastewater treatment process to details about...... guide to the microbes of activated sludge by comparing microbial community composition in 32 WWTPs located worldwide. This will facilitate a better understanding of the ecology of the ecosystem of activated sludge. Reference: McIlroy et al. MiDAS: the field guide to the microbes of activated sludge...... on a survey of 25 full-scale Danish wastewater treatment plants over 6 years and using MiDAS taxonomy, we have collected more than 150 key organisms in activated sludge wastewater treatment systems, linked their identity with available information on their function and distribution and included...

  17. The MIDAS telescope for microwave detection of ultra-high energy cosmic rays

    Science.gov (United States)

    Alvarez-Muñiz, J.; Amaral Soares, E.; Berlin, A.; Bogdan, M.; Boháčová, M.; Bonifazi, C.; Carvalho, W. R.; de Mello Neto, J. R. T.; Facal San Luis, P.; Genat, J. F.; Hollon, N.; Mills, E.; Monasor, M.; Privitera, P.; Ramos de Castro, A.; Reyes, L. C.; Richardson, M.; Rouille d'Orfeuil, B.; Santos, E. M.; Wayne, S.; Williams, C.; Zas, E.; Zhou, J.

    2013-08-01

    We present the design, implementation and data taking performance of the MIcrowave Detection of Air Showers (MIDAS) experiment, a large field of view imaging telescope designed to detect microwave radiation from extensive air showers induced by ultra-high energy cosmic rays. This novel technique may bring a tenfold increase in detector duty cycle when compared to the standard fluorescence technique based on detection of ultraviolet photons. The MIDAS telescope consists of a 4.5 m diameter dish with a 53-pixel receiver camera, instrumented with feed horns operating in the commercial extended C-Band (3.4-4.2 GHz). A self-trigger capability is implemented in the digital electronics. The main objectives of this first prototype of the MIDAS telescope - to validate the telescope design, and to demonstrate a large detector duty cycle - were successfully accomplished in a dedicated data taking run at the University of Chicago campus prior to installation at the Pierre Auger Observatory.

  18. Simulation of the condensation experiment for the SG primary of SMART with MIDAS/SMR

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jong Hwa; Kim, Dong Ha; Chung, Young Jong; Park, Sun Hee [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Cho, Seong Won [Korea Radiation Technology Institute Co., Daejeon (Korea, Republic of)

    2012-05-15

    SMART is new concept of reactor that all the main components such as the steam generator, the coolant pumps and the pressurizer are located inside the reactor vessel. MIDAS/SMR V1.0.3 code has been used for estimating the severe accident from SMART. SMART has the SG tube with helical shape that is different from that of PWR. MIDAS code has the condensation model for the both sides of surfaces from the various kinds of geometry. But it does not have the condensation model for the helical type of tube. In this study, the condensation experiment for the outer surface of the SG tube in SMART that was performed by Po-Hang university was simulated with MIDAS/SMR under the assumption of straight pipe. The simulation results showed well predictions of the amount of heat removal from the SG tube primary side and thermal hydraulic parameters

  19. The Virtual Midas Touch: Helping Behavior After a Mediated Social Touch.

    Science.gov (United States)

    Haans, A; Usselsteijn, W A

    2009-01-01

    A brief touch on the upper arm increases people's altruistic behavior and willingness to comply with a request. In this paper, we investigate whether this Midas touch phenomenon would also occur under mediated conditions (i.e., touching via an arm strap equipped with electromechanical actuators). Helping behavior was more frequently endorsed in the touch, compared to the no-touch condition, but this difference was not found to be statistically significant. However, a meta-analytical comparison with published research demonstrated that the strength of the virtual Midas touch is of the same magnitude as that of the Midas touch in unmediated situations. The present experiment, thus, provides empirical evidence that touch-like qualities can be attributed to electromechanical stimulation. This is important for the field of mediated social touch of which the design rationale is based on the assumption that mediated touch by means of tactile feedback technologies is processed in ways similar to real physical contact.

  20. Simulation of the condensation experiment for the SG primary of SMART with MIDAS/SMR

    International Nuclear Information System (INIS)

    Park, Jong Hwa; Kim, Dong Ha; Chung, Young Jong; Park, Sun Hee; Cho, Seong Won

    2012-01-01

    SMART is new concept of reactor that all the main components such as the steam generator, the coolant pumps and the pressurizer are located inside the reactor vessel. MIDAS/SMR V1.0.3 code has been used for estimating the severe accident from SMART. SMART has the SG tube with helical shape that is different from that of PWR. MIDAS code has the condensation model for the both sides of surfaces from the various kinds of geometry. But it does not have the condensation model for the helical type of tube. In this study, the condensation experiment for the outer surface of the SG tube in SMART that was performed by Po-Hang university was simulated with MIDAS/SMR under the assumption of straight pipe. The simulation results showed well predictions of the amount of heat removal from the SG tube primary side and thermal hydraulic parameters

  1. MIDAS, prototype Multivariate Interactive Digital Analysis System, phase 1. Volume 3: Wiring diagrams

    Science.gov (United States)

    Kriegler, F. J.; Christenson, D.; Gordon, M.; Kistler, R.; Lampert, S.; Marshall, R.; Mclaughlin, R.

    1974-01-01

    The Midas System is a third-generation, fast, multispectral recognition system able to keep pace with the large quantity and high rates of data acquisition from present and projected sensors. A principal objective of the MIDAS Program is to provide a system well interfaced with the human operator and thus to obtain large overall reductions in turn-around time and significant gains in throughput. The hardware and software generated in Phase I of the overall program are described. The system contains a mini-computer to control the various high-speed processing elements in the data path and a classifier which implements an all-digital prototype multivariate-Gaussian maximum likelihood decision algorithm operating at 2 x 100,000 pixels/sec. Sufficient hardware was developed to perform signature extraction from computer-compatible tapes, compute classifier coefficients, control the classifier operation, and diagnose operation. The MIDAS construction and wiring diagrams are given.

  2. MIDAS, prototype Multivariate Interactive Digital Analysis System, Phase 1. Volume 2: Diagnostic system

    Science.gov (United States)

    Kriegler, F. J.; Christenson, D.; Gordon, M.; Kistler, R.; Lampert, S.; Marshall, R.; Mclaughlin, R.

    1974-01-01

    The MIDAS System is a third-generation, fast, multispectral recognition system able to keep pace with the large quantity and high rates of data acquisition from present and projected sensors. A principal objective of the MIDAS Program is to provide a system well interfaced with the human operator and thus to obtain large overall reductions in turn-around time and significant gains in throughout. The hardware and software generated in Phase I of the over-all program are described. The system contains a mini-computer to control the various high-speed processing elements in the data path and a classifier which implements an all-digital prototype multivariate-Gaussian maximum likelihood decision algorithm operating 2 x 105 pixels/sec. Sufficient hardware was developed to perform signature extraction from computer-compatible tapes, compute classifier coefficients, control the classifier operation, and diagnose operation. Diagnostic programs used to test MIDAS' operations are presented.

  3. Rapid and Parallel Adaptive Evolution of the Visual System of Neotropical Midas Cichlid Fishes.

    Science.gov (United States)

    Torres-Dowdall, Julián; Pierotti, Michele E R; Härer, Andreas; Karagic, Nidal; Woltering, Joost M; Henning, Frederico; Elmer, Kathryn R; Meyer, Axel

    2017-10-01

    Midas cichlid fish are a Central American species flock containing 13 described species that has been dated to only a few thousand years old, a historical timescale infrequently associated with speciation. Their radiation involved the colonization of several clear water crater lakes from two turbid great lakes. Therefore, Midas cichlids have been subjected to widely varying photic conditions during their radiation. Being a primary signal relay for information from the environment to the organism, the visual system is under continuing selective pressure and a prime organ system for accumulating adaptive changes during speciation, particularly in the case of dramatic shifts in photic conditions. Here, we characterize the full visual system of Midas cichlids at organismal and genetic levels, to determine what types of adaptive changes evolved within the short time span of their radiation. We show that Midas cichlids have a diverse visual system with unexpectedly high intra- and interspecific variation in color vision sensitivity and lens transmittance. Midas cichlid populations in the clear crater lakes have convergently evolved visual sensitivities shifted toward shorter wavelengths compared with the ancestral populations from the turbid great lakes. This divergence in sensitivity is driven by changes in chromophore usage, differential opsin expression, opsin coexpression, and to a lesser degree by opsin coding sequence variation. The visual system of Midas cichlids has the evolutionary capacity to rapidly integrate multiple adaptations to changing light environments. Our data may indicate that, in early stages of divergence, changes in opsin regulation could precede changes in opsin coding sequence evolution. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  4. MIDAS robust trend estimator for accurate GPS station velocities without step detection

    Science.gov (United States)

    Blewitt, Geoffrey; Kreemer, Corné; Hammond, William C.; Gazeaux, Julien

    2016-03-01

    Automatic estimation of velocities from GPS coordinate time series is becoming required to cope with the exponentially increasing flood of available data, but problems detectable to the human eye are often overlooked. This motivates us to find an automatic and accurate estimator of trend that is resistant to common problems such as step discontinuities, outliers, seasonality, skewness, and heteroscedasticity. Developed here, Median Interannual Difference Adjusted for Skewness (MIDAS) is a variant of the Theil-Sen median trend estimator, for which the ordinary version is the median of slopes vij = (xj-xi)/(tj-ti) computed between all data pairs i > j. For normally distributed data, Theil-Sen and least squares trend estimates are statistically identical, but unlike least squares, Theil-Sen is resistant to undetected data problems. To mitigate both seasonality and step discontinuities, MIDAS selects data pairs separated by 1 year. This condition is relaxed for time series with gaps so that all data are used. Slopes from data pairs spanning a step function produce one-sided outliers that can bias the median. To reduce bias, MIDAS removes outliers and recomputes the median. MIDAS also computes a robust and realistic estimate of trend uncertainty. Statistical tests using GPS data in the rigid North American plate interior show ±0.23 mm/yr root-mean-square (RMS) accuracy in horizontal velocity. In blind tests using synthetic data, MIDAS velocities have an RMS accuracy of ±0.33 mm/yr horizontal, ±1.1 mm/yr up, with a 5th percentile range smaller than all 20 automatic estimators tested. Considering its general nature, MIDAS has the potential for broader application in the geosciences.

  5. A preliminary psychometric evaluation of Music in Dementia Assessment Scales (MiDAS)

    DEFF Research Database (Denmark)

    McDermott, Orii; Orgeta, Vasiliki; Ridder, Hanne Mette Ochsner

    2014-01-01

    despite the small sample size. Future research with a larger sample size could provide a more in-depth psychometric evaluation, including further exploration of the underlying factors. MiDAS provides a measure of engagement with musical experience and offers insight into who is likely to benefit on other......Background: Music in Dementia Assessment Scales (MiDAS), an observational outcome measure for music therapy with people with moderate to severe dementia, was developed from qualitative data of focus groups and interviews. Expert and peer consultations were conducted at each stage of the scale...

  6. Importance of the macroeconomic variables for variance prediction: A GARCH-MIDAS approach

    DEFF Research Database (Denmark)

    Asgharian, Hossein; Hou, Ai Jun; Javed, Farrukh

    2013-01-01

    This paper aims to examine the role of macroeconomic variables in forecasting the return volatility of the US stock market. We apply the GARCH-MIDAS (Mixed Data Sampling) model to examine whether information contained in macroeconomic variables can help to predict short-term and long-term compone......This paper aims to examine the role of macroeconomic variables in forecasting the return volatility of the US stock market. We apply the GARCH-MIDAS (Mixed Data Sampling) model to examine whether information contained in macroeconomic variables can help to predict short-term and long...

  7. How MIDAS improved our understanding of micrometre-sized cometary dust

    Science.gov (United States)

    Mannel, T.; Bentley, M. S.; Boakes, P.; Jeszenszky, H.; Levasseur-Regourd, A. C.; Schmied, R.; Torkar, K.

    2017-09-01

    The MIDAS atomic force microscope on the Rosetta orbiter was an instrument developed to investigate, for the first time, the morphology of nearly unaltered cometary dust. It acquired the 3D topography of about 1 - 50 µm sized dust particles with resolutions down to a few nanometres. These images showed the agglomerate character of the dust and confirmed that the smallest subunit sizes were less than 100 nm. MIDAS acquired the first direct proof of a fractal dust particle, opening a new approach to investigate the history of our early Solar System and of comets.

  8. Simulation of the VISTA SG heat transfer experiment using MIDAS/SMR

    International Nuclear Information System (INIS)

    Park, Jong Hwa; Kim, Dong Ha; Chung, Young Jong; Park, Sun Hee; Cho, Seong Won

    2011-01-01

    As the SMART plant was designed with the helical type tubes in the steam generators, the heat transfer model in that geometry has been implemented in the TASS/SMR-S code and used for the safety analysis. The same correlation was implemented in the MIDAS/SMR, which is being used for the severe accident analyses, to model heat transfer at the steam generators. In this study, the VISTA SG experiment with the helical steam generator tube was simulated with MIDAS/SMR to compare the heat transfer rates through the helical tube

  9. Rasch Analysis of Lebanese Nurses’ Responses to the EIS Questionnaire

    Directory of Open Access Journals (Sweden)

    Michael Clinton

    2014-08-01

    Full Text Available This study examined the psychometric characteristics of a 32-item modified version of the Ethical Issues Scale (EIS. Data were collected from 59 registered nurses at the American University of Beirut Medical Centre (AUBMC. Data were analyzed using WINSTEPS Rasch analysis software. The four-category EIS rating scale needs modification for future studies in Lebanon. All EIS scale items need rewording prior to translation into Arabic to avoid confusion among Lebanese nurses. Principal component analysis (PCA of residuals indicated the possible presence of additional dimensions. Additional EIS items are needed to improve targeting.

  10. EI: A Program for Ecological Inference

    Directory of Open Access Journals (Sweden)

    Gary King

    2004-09-01

    Full Text Available The program EI provides a method of inferring individual behavior from aggregate data. It implements the statistical procedures, diagnostics, and graphics from the book A Solution to the Ecological Inference Problem: Reconstructing Individual Behavior from Aggregate Data (King 1997. Ecological inference, as traditionally defined, is the process of using aggregate (i.e., "ecological" data to infer discrete individual-level relationships of interest when individual-level data are not available. Ecological inferences are required in political science research when individual-level surveys are unavailable (e.g., local or comparative electoral politics, unreliable (racial politics, insufficient (political geography, or infeasible (political history. They are also required in numerous areas of ma jor significance in public policy (e.g., for applying the Voting Rights Act and other academic disciplines ranging from epidemiology and marketing to sociology and quantitative history.

  11. Narbalek uranium mine: from EIS to decommissioning

    International Nuclear Information System (INIS)

    Waggitt, P.W.

    2000-01-01

    The Nabarlek uranium mine operated in Northern Australia from 1979 until 1989 and was the first of the 'new generation' of uranium mines to go through the cycle of EIS, operation and decommissioning. The paper describes the environmental and operational approval processes, the regulatory regime and the decommissioning procedures at the mine. The mine was located on land owned by indigenous Aboriginal people and so there were serious cultural considerations to be taken into account throughout the mine's life. Site work for decommissioning and rehabilitation was completed in 1995 but revegetation assessment has continued until the present time (1999). The paper concludes with the latest assessment and monitoring data and discusses the lessons learned by all parties from the completion of the cycle of mine life 'from cradle to grave'. (author)

  12. Eestlane ei kummarda kulda nagu hindu / Toivo Tänavsuu

    Index Scriptorium Estoniae

    Tänavsuu, Toivo

    2005-01-01

    Šveitsi kullatehase MKS Finance S.A. asepresidendi Frederic Panizzutti sõnul on kuld lääneriikides investeerimisobjekt, mida hoitakse kodus ega müüda tagasi ühelgi põhjusel. Firma Tavid müüb kulda kõigis Balti riikides, sellest suurem osa ostetakse Lätis. Eesti Panga avalike suhete juhi Silver Vohu sõnul keskpangad pigem vähendavad kulla osakaalu oma reservides

  13. Translation, cross-cultural adaptation and reliability of the German version of the migraine disability assessment (MIDAS) questionnaire.

    Science.gov (United States)

    Benz, Thomas; Lehmann, Susanne; Gantenbein, Andreas R; Sandor, Peter S; Stewart, Walter F; Elfering, Achim; Aeschlimann, André G; Angst, Felix

    2018-03-09

    The Migraine Disability Assessment (MIDAS) is a brief questionnaire and measures headache-related disability. This study aimed to translate and cross-culturally adapt the original English version of the MIDAS to German and to test its reliability. The standardized translation process followed international guidelines. The pre-final version was tested for clarity and comprehensibility by 34 headache sufferers. Test-retest reliability of the final version was quantified by 36 headache patients completing the MIDAS twice with an interval of 48 h. Reliability was determined by intraclass correlation coefficients and internal consistency by Cronbach's α. All steps of the translation process were followed, documented and approved by the developer of the MIDAS. The expert committee discussed in detail the complex phrasing of the questions that refer to one to another, especially exclusion of headache-days from one item to the next. The German version contains more active verb sentences and prefers the perfect to the imperfect tense. The MIDAS scales intraclass correlation coefficients ranged from 0.884 to 0.994 and was 0.991 (95% CI: 0.982-0.995) for the MIDAS total score. Cronbach's α for the MIDAS as a whole was 0.69 at test and 0.67 at retest. The translation process was challenged by the comprehensibility of the questionnaire. The German version of the MIDAS is a highly reliable instrument for assessing headache related disability with moderate internal consistency. Provided validity testing of the German MIDAS is successful, it can be recommended for use in clinical practice as well as in research.

  14. Man-Machine Integrated Design and Analysis System (MIDAS): Functional Overview

    Science.gov (United States)

    Corker, Kevin; Neukom, Christian

    1998-01-01

    Included in the series of screen print-outs illustrates the structure and function of the Man-Machine Integrated Design and Analysis System (MIDAS). Views into the use of the system and editors are featured. The use-case in this set of graphs includes the development of a simulation scenario.

  15. [Mida väärtustada ja arendada koolis...] / Maria Tiro

    Index Scriptorium Estoniae

    Tiro, Maria

    2009-01-01

    Mida väärtustada ja arendada koolis ajal, mil Eesti paljudes paikades õpilaste arv väheneb ning inimesed koonduvad linnade ümbrusesse? Rae valla näite põhjal Jüri Gümnaasiumi direktor Maria Tiro

  16. Default probabilities, CDS premiums and downgrades : A probit-MIDAS analysis

    NARCIS (Netherlands)

    Freitag, L.

    2014-01-01

    This paper examines the relationship between sovereign credit default swaps (CDS) and sovereign rating changes of European countries. To this aim, a new estimator is introduced which merges mixed data sampling (MIDAS) with probit regression. Simulations show that the estimator has good properties in

  17. Sensitivity analysis of MIDAS tests using SPACE code. Effect of nodalization

    International Nuclear Information System (INIS)

    Eom, Shin; Oh, Seung-Jong; Diab, Aya

    2018-01-01

    The nodalization sensitivity analysis for the ECCS (Emergency Core Cooling System) bypass phe�nomena was performed using the SPACE (Safety and Performance Analysis CodE) thermal hydraulic analysis computer code. The results of MIDAS (Multi-�dimensional Investigation in Downcomer Annulus Simulation) test were used. The MIDAS test was conducted by the KAERI (Korea Atomic Energy Research Institute) for the performance evaluation of the ECC (Emergency Core Cooling) bypass phenomenon in the DVI (Direct Vessel Injection) system. The main aim of this study is to examine the sensitivity of the SPACE code results to the number of thermal hydraulic channels used to model the annulus region in the MIDAS experiment. The numerical model involves three nodalization cases (4, 6, and 12 channels) and the result show that the effect of nodalization on the bypass fraction for the high steam flow rate MIDAS tests is minimal. For computational efficiency, a 4 channel representation is recommended for the SPACE code nodalization. For the low steam flow rate tests, the SPACE code over-�predicts the bypass fraction irrespective of the nodalization finesse. The over-�prediction at low steam flow may be attributed to the difficulty to accurately represent the flow regime in the vicinity of the broken cold leg.

  18. A virtual Midas touch? : touch, compliance, and confederate bias in mediated communication

    NARCIS (Netherlands)

    Haans, A.; Bruijn, de R.; IJsselsteijn, W.A.

    2014-01-01

    A brief touch to the shoulder or upper arm increases people’s helping behavior and willingness to comply with requests. In this manuscript, we investigate whether this well-known Midas touch effect is also operative in mediated interactions where the touch act is replaced by electromechanical

  19. The virtual midas touch : helping behavior after a mediated social touch

    NARCIS (Netherlands)

    Haans, A.; IJsselsteijn, W.A.

    2009-01-01

    A brief touch on the upper arm increases people's altruistic behavior and willingness to comply with a request. In this paper, we investigate whether this Midas touch phenomenon would also occur under mediated conditions (i.e., touching via an arm strap equipped with electromechanical actuators).

  20. MIDAS: a practical Bayesian design for platform trials with molecularly targeted agents.

    Science.gov (United States)

    Yuan, Ying; Guo, Beibei; Munsell, Mark; Lu, Karen; Jazaeri, Amir

    2016-09-30

    Recent success of immunotherapy and other targeted therapies in cancer treatment has led to an unprecedented surge in the number of novel therapeutic agents that need to be evaluated in clinical trials. Traditional phase II clinical trial designs were developed for evaluating one candidate treatment at a time and thus not efficient for this task. We propose a Bayesian phase II platform design, the multi-candidate iterative design with adaptive selection (MIDAS), which allows investigators to continuously screen a large number of candidate agents in an efficient and seamless fashion. MIDAS consists of one control arm, which contains a standard therapy as the control, and several experimental arms, which contain the experimental agents. Patients are adaptively randomized to the control and experimental agents based on their estimated efficacy. During the trial, we adaptively drop inefficacious or overly toxic agents and 'graduate' the promising agents from the trial to the next stage of development. Whenever an experimental agent graduates or is dropped, the corresponding arm opens immediately for testing the next available new agent. Simulation studies show that MIDAS substantially outperforms the conventional approach. The proposed design yields a significantly higher probability for identifying the promising agents and dropping the futile agents. In addition, MIDAS requires only one master protocol, which streamlines trial conduct and substantially decreases the overhead burden. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  1. The virtual Midas touch : helping behavior after a mediated social touch

    NARCIS (Netherlands)

    Haans, A.; IJsselsteijn, W.A.; Graus, M.P.; Salminen, J.A.

    2008-01-01

    A brief touch on the upper arm increases people's altruistic behavior and willingness to comply to a request. In this paper, we investigate whether this Midas Touch effect would also occur under mediated conditions (i.e., a text messaging system and an arm strap equipped with vibrotactile

  2. MiDAS: the field guide to the microbes of activated sludge.

    Science.gov (United States)

    McIlroy, Simon Jon; Saunders, Aaron Marc; Albertsen, Mads; Nierychlo, Marta; McIlroy, Bianca; Hansen, Aviaja Anna; Karst, Søren Michael; Nielsen, Jeppe Lund; Nielsen, Per Halkjær

    2015-01-01

    The Microbial Database for Activated Sludge (MiDAS) field guide is a freely available online resource linking the identity of abundant and process critical microorganisms in activated sludge wastewater treatment systems to available data related to their functional importance. Phenotypic properties of some of these genera are described, but most are known only from sequence data. The MiDAS taxonomy is a manual curation of the SILVA taxonomy that proposes a name for all genus-level taxa observed to be abundant by large-scale 16 S rRNA gene amplicon sequencing of full-scale activated sludge communities. The taxonomy can be used to classify unknown sequences, and the online MiDAS field guide links the identity to the available information about their morphology, diversity, physiology and distribution. The use of a common taxonomy across the field will provide a solid foundation for the study of microbial ecology of the activated sludge process and related treatment processes. The online MiDAS field guide is a collaborative workspace intended to facilitate a better understanding of the ecology of activated sludge and related treatment processes--knowledge that will be an invaluable resource for the optimal design and operation of these systems. © The Author(s) 2015. Published by Oxford University Press.

  3. Sensitivity analysis of MIDAS tests using SPACE code. Effect of nodalization

    Energy Technology Data Exchange (ETDEWEB)

    Eom, Shin; Oh, Seung-Jong; Diab, Aya [KEPCO International Nuclear Graduate School (KINGS), Ulsan (Korea, Republic of). Dept. of NPP Engineering

    2018-02-15

    The nodalization sensitivity analysis for the ECCS (Emergency Core Cooling System) bypass phe�nomena was performed using the SPACE (Safety and Performance Analysis CodE) thermal hydraulic analysis computer code. The results of MIDAS (Multi-�dimensional Investigation in Downcomer Annulus Simulation) test were used. The MIDAS test was conducted by the KAERI (Korea Atomic Energy Research Institute) for the performance evaluation of the ECC (Emergency Core Cooling) bypass phenomenon in the DVI (Direct Vessel Injection) system. The main aim of this study is to examine the sensitivity of the SPACE code results to the number of thermal hydraulic channels used to model the annulus region in the MIDAS experiment. The numerical model involves three nodalization cases (4, 6, and 12 channels) and the result show that the effect of nodalization on the bypass fraction for the high steam flow rate MIDAS tests is minimal. For computational efficiency, a 4 channel representation is recommended for the SPACE code nodalization. For the low steam flow rate tests, the SPACE code over-�predicts the bypass fraction irrespective of the nodalization finesse. The over-�prediction at low steam flow may be attributed to the difficulty to accurately represent the flow regime in the vicinity of the broken cold leg.

  4. 33 CFR 230.13 - Environmental Impact Statement (EIS).

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Environmental Impact Statement..., DEPARTMENT OF DEFENSE PROCEDURES FOR IMPLEMENTING NEPA § 230.13 Environmental Impact Statement (EIS). An EIS... issues and impacts. The transmittal letter to EPA as well as the cover sheet should clearly identify the...

  5. Piirivalve : radar piiritusevoolikut ei püüa

    Index Scriptorium Estoniae

    2004-01-01

    Piirivalvet kritiseeriti selle eest, et see ei märganud salapiirituse veoks paigaldatud voolikut Narva veehoidlas. Ida-Viru piirkonnaülema Roland Peetsi sõnul ei ole ükski radar võimeline fikseerima liikumist vee all

  6. Euroopa paindumatus Eestile eurot ei luba / Hindrek Riikoja

    Index Scriptorium Estoniae

    Riikoja, Hindrek

    2006-01-01

    Vt. ka Postimees : na russkom jazõke 17. juuli lk. 9. 14. juulil Eesti rahandusministri Aivar Sõerdi ja peaminister Andrus Ansipiga kohtunud Euroopa Komisjoni rahandusvolinik Joaquin Almunia kinnitas, et Eestil ei maksa loota eurokriteeriumide muutmisele, rahandusvoliniku hinnangul Eesti krooni devalveerimine enne eurole üleminekut ei ole vajalik

  7. Adaptive phenotypic plasticity in the Midas cichlid fish pharyngeal jaw and its relevance in adaptive radiation

    Directory of Open Access Journals (Sweden)

    Salzburger Walter

    2011-04-01

    Full Text Available Abstract Background Phenotypic evolution and its role in the diversification of organisms is a central topic in evolutionary biology. A neglected factor during the modern evolutionary synthesis, adaptive phenotypic plasticity, more recently attracted the attention of many evolutionary biologists and is now recognized as an important ingredient in both population persistence and diversification. The traits and directions in which an ancestral source population displays phenotypic plasticity might partly determine the trajectories in morphospace, which are accessible for an adaptive radiation, starting from the colonization of a novel environment. In the case of repeated colonizations of similar environments from the same source population this "flexible stem" hypothesis predicts similar phenotypes to arise in repeated subsequent radiations. The Midas Cichlid (Amphilophus spp. in Nicaragua has radiated in parallel in several crater-lakes seeded by populations originating from the Nicaraguan Great Lakes. Here, we tested phenotypic plasticity in the pharyngeal jaw of Midas Cichlids. The pharyngeal jaw apparatus of cichlids, a second set of jaws functionally decoupled from the oral ones, is known to mediate ecological specialization and often differs strongly between sister-species. Results We performed a common garden experiment raising three groups of Midas cichlids on food differing in hardness and calcium content. Analyzing the lower pharyngeal jaw-bones we find significant differences between diet groups qualitatively resembling the differences found between specialized species. Observed differences in pharyngeal jaw expression between groups were attributable to the diet's mechanical resistance, whereas surplus calcium in the diet was not found to be of importance. Conclusions The pharyngeal jaw apparatus of Midas Cichlids can be expressed plastically if stimulated mechanically during feeding. Since this trait is commonly differentiated - among

  8. Adaptive phenotypic plasticity in the Midas cichlid fish pharyngeal jaw and its relevance in adaptive radiation.

    Science.gov (United States)

    Muschick, Moritz; Barluenga, Marta; Salzburger, Walter; Meyer, Axel

    2011-04-30

    Phenotypic evolution and its role in the diversification of organisms is a central topic in evolutionary biology. A neglected factor during the modern evolutionary synthesis, adaptive phenotypic plasticity, more recently attracted the attention of many evolutionary biologists and is now recognized as an important ingredient in both population persistence and diversification. The traits and directions in which an ancestral source population displays phenotypic plasticity might partly determine the trajectories in morphospace, which are accessible for an adaptive radiation, starting from the colonization of a novel environment. In the case of repeated colonizations of similar environments from the same source population this "flexible stem" hypothesis predicts similar phenotypes to arise in repeated subsequent radiations. The Midas Cichlid (Amphilophus spp.) in Nicaragua has radiated in parallel in several crater-lakes seeded by populations originating from the Nicaraguan Great Lakes. Here, we tested phenotypic plasticity in the pharyngeal jaw of Midas Cichlids. The pharyngeal jaw apparatus of cichlids, a second set of jaws functionally decoupled from the oral ones, is known to mediate ecological specialization and often differs strongly between sister-species. We performed a common garden experiment raising three groups of Midas cichlids on food differing in hardness and calcium content. Analyzing the lower pharyngeal jaw-bones we find significant differences between diet groups qualitatively resembling the differences found between specialized species. Observed differences in pharyngeal jaw expression between groups were attributable to the diet's mechanical resistance, whereas surplus calcium in the diet was not found to be of importance. The pharyngeal jaw apparatus of Midas Cichlids can be expressed plastically if stimulated mechanically during feeding. Since this trait is commonly differentiated--among other traits--between Midas Cichlid species, its plasticity

  9. The structure of cometary dust - first results from the MIDAS Atomic Force Microscope onboard Rosetta

    Science.gov (United States)

    Bentley, M. S.; Torkar, K.; Romstedt, J.

    2014-12-01

    A decade after launch the European Space Agency's Rosetta spacecraft has finally arrived at comet 67P/Churyumov-Gerasimenko. Unlike previous cometary missions, Rosetta is not a flyby, limited to taking a snapshot of the comet at a single heliocentric distance. Instead, Rosetta intercepted the comet prior to the onset of major activity and will chart its evolution during its perihelion passage and beyond. Such a unique mission requires a unique payload; as well as the more typical remote sensing instruments, Rosetta also carries sensors to sample in situ the gas and dust environment. One of these instruments is MIDAS, an atomic force microscope designed to collect dust and image it in three dimensions with nanometre resolution. Equipped with an array of sharp tips, four of which are magnetised to allow magnetic force microscopy, MIDAS exposes targets to the incident flux after which they are moved to the microscope for analysis. As well as extending coverage of the dust size distribution down to the finest particles, MIDAS has the unique capability to determine the shape of pristine particles - to determine, for example, if they are compact or fluffy, and to look for features which may be diagnostic of their formation environment or evolution. The magnetic mode lets MIDAS probe samples for magnetic material and to map its location if present. Having been operating almost continuously after hibernation imaging empty targets before exposure, the first exposures were performed when Rosetta entered 30 km bound orbits. The first MIDAS images and analyses of collected dust grains are presented here.

  10. MIDAS: Mining differentially activated subpaths of KEGG pathways from multi-class RNA-seq data.

    Science.gov (United States)

    Lee, Sangseon; Park, Youngjune; Kim, Sun

    2017-07-15

    Pathway based analysis of high throughput transcriptome data is a widely used approach to investigate biological mechanisms. Since a pathway consists of multiple functions, the recent approach is to determine condition specific sub-pathways or subpaths. However, there are several challenges. First, few existing methods utilize explicit gene expression information from RNA-seq. More importantly, subpath activity is usually an average of statistical scores, e.g., correlations, of edges in a candidate subpath, which fails to reflect gene expression quantity information. In addition, none of existing methods can handle multiple phenotypes. To address these technical problems, we designed and implemented an algorithm, MIDAS, that determines condition specific subpaths, each of which has different activities across multiple phenotypes. MIDAS utilizes gene expression quantity information fully and the network centrality information to determine condition specific subpaths. To test performance of our tool, we used TCGA breast cancer RNA-seq gene expression profiles with five molecular subtypes. 36 differentially activate subpaths were determined. The utility of our method, MIDAS, was demonstrated in four ways. All 36 subpaths are well supported by the literature information. Subsequently, we showed that these subpaths had a good discriminant power for five cancer subtype classification and also had a prognostic power in terms of survival analysis. Finally, in a performance comparison of MIDAS to a recent subpath prediction method, PATHOME, our method identified more subpaths and much more genes that are well supported by the literature information. http://biohealth.snu.ac.kr/software/MIDAS/. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  11. Värviline revolutsioon Eestis? / Ivar Tallo

    Index Scriptorium Estoniae

    Tallo, Ivar, 1964-

    2009-01-01

    Autor viitab kohalike valimiste tulemustele järgnenud valulikule reaktsioonile avalikus meediaruumis. Järgmist, valimistevahelist aastat tuleb kasutada ühiskonna lepitamiseks ja ratsionaalse poliitikakäitumise edendamiseks

  12. Cannes : seks ja revolutsioon / Annika Koppel

    Index Scriptorium Estoniae

    Koppel, Annika

    2006-01-01

    Cannes'i filmifestival. Nähtud filmidest : Ron Howardi "Da Vinci kood"("The Code Da Vinci"), hiinlase Lou Ye "Suvepalee", inglase Ken Loach'i "Tuul, mis sasib odrapõldu" ("The Wind that Shakes the Barely"), ungarlase Györgi Palfi "Taksidermia"

  13. Internet ees, revolutsioon taga / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2011-01-01

    Internetiühendus on Tuneesias vähemalt igal kolmandal ja Egiptuses igal neljandal. Mobiiltelefone on Tuneesias 10 mln. elaniku kohta 9,7 mln., Egiptuses 80 mln. elaniku kohta 55 mln. Autor leiab, et kui islamimaailm suutis omaks võtta moodsa kommunikatsiooni, suudab ta ilmselt omaks võtta ka demokraatia. Interneti levikut pidurdavad diktatuuririigid

  14. The Influence of Emotional Intelligence (EI) on Coping and Mental Health in Adolescence: Divergent Roles for Trait and Ability EI

    Science.gov (United States)

    Davis, Sarah K.; Humphrey, Neil

    2012-01-01

    Theoretically, trait and ability emotional intelligence (EI) should mobilise coping processes to promote adaptation, plausibly operating as personal resources determining choice and/or implementation of coping style. However, there is a dearth of research deconstructing if/how EI impacts mental health via multiple coping strategies in adolescence.…

  15. Detection and localisation of the abalone probiotic Vibrio midae SY9 and its extracellular protease, VmproA, within the digestive tract of the South African abalone, Haliotis midae.

    Directory of Open Access Journals (Sweden)

    Robert J Huddy

    Full Text Available Probiotics have been widely reported to increase the growth rate of commercially important fish and shellfish by enhancing the digestion of ingested feed through the production of extracellular enzymes such as proteases and alginases. In order to investigate this further, the objective of this study was to localise the bacterial probiont Vibrio midae SY9 and one of the extracellular proteases it produces in the digestive tract of the South African abalone Haliotis midae. This was accomplished by inserting a promotorless gfp gene into the chromosome of the bacterium which was incorporated in an artificial, fishmeal-based abalone feed. In situ histological comparison of abalone fed either a basal diet or the basal diet supplemented with V. midae SY9::Tn10.52 using a cocktail of DNA probes to the gfp gene localised the probiont to the crop/stomach and intestinal regions of the H. midae digestive tract. Generally, the ingested probiotic bacterium occurred in association with feed and particulate matter within the crop/stomach and intestinal regions, as well as adhered to the wall of the crop/stomach. Histological immunohistochemical examination using polyclonal anti-VmproA antibodies localised an extracellular protease produced by V. midae SY9 to the H. midae crop/stomach and intestine where it appeared to be associated with feed and/or other particulate matter in the abalone gut. Thus the data suggests that V. midae SY9 colonises and/or adheres to the mucous lining of the abalone gut. Furthermore, the close association observed between the bacterium, its extracellular protease and ingested feed particles supports the theory that V. midae SY9 elevates in situ digestive enzyme levels and thus enhances feed digestion in farmed abalone.

  16. Detection and localisation of the abalone probiotic Vibrio midae SY9 and its extracellular protease, VmproA, within the digestive tract of the South African abalone, Haliotis midae.

    Science.gov (United States)

    Huddy, Robert J; Coyne, Vernon E

    2014-01-01

    Probiotics have been widely reported to increase the growth rate of commercially important fish and shellfish by enhancing the digestion of ingested feed through the production of extracellular enzymes such as proteases and alginases. In order to investigate this further, the objective of this study was to localise the bacterial probiont Vibrio midae SY9 and one of the extracellular proteases it produces in the digestive tract of the South African abalone Haliotis midae. This was accomplished by inserting a promotorless gfp gene into the chromosome of the bacterium which was incorporated in an artificial, fishmeal-based abalone feed. In situ histological comparison of abalone fed either a basal diet or the basal diet supplemented with V. midae SY9::Tn10.52 using a cocktail of DNA probes to the gfp gene localised the probiont to the crop/stomach and intestinal regions of the H. midae digestive tract. Generally, the ingested probiotic bacterium occurred in association with feed and particulate matter within the crop/stomach and intestinal regions, as well as adhered to the wall of the crop/stomach. Histological immunohistochemical examination using polyclonal anti-VmproA antibodies localised an extracellular protease produced by V. midae SY9 to the H. midae crop/stomach and intestine where it appeared to be associated with feed and/or other particulate matter in the abalone gut. Thus the data suggests that V. midae SY9 colonises and/or adheres to the mucous lining of the abalone gut. Furthermore, the close association observed between the bacterium, its extracellular protease and ingested feed particles supports the theory that V. midae SY9 elevates in situ digestive enzyme levels and thus enhances feed digestion in farmed abalone.

  17. Cynthia Kaplan : Venemaa ei suuda mõista, mida tähendab suveräänsetest rahvusriikidest naabrite omamine / Cynthia Kaplan ; interv. Liisa Past

    Index Scriptorium Estoniae

    Kaplan, Cynthia

    2007-01-01

    California ülikooli politoloogiaprofessor, Eesti-ekspert vastab küsimustele, kas tavaliste eestlaste ja venelaste puhul toimib identiteet ja suhe oma riigiga erinevalt, kas on reaalne leida peale rahvusliku identiteedi ka riigi- või kodanikuidentiteet, kas ta suhtub skeptiliselt mõttesse leida Eestis ühine ajalugu, kas Venemaal on endiselt imperialistlikke ambitsioone teiste riikide suhtes

  18. 1) Mis teile praeguses eesti kirjanduses ei meeldi? 2) Mida tuleks teha, et asi läheks nii, nagu teile meeldib? : [küsitlus

    Index Scriptorium Estoniae

    2002-01-01

    Vastavad : Vaapo Vaher, Elo Lindsalu, Olev Remsu, Jüri Ehlvest, François Serpent, Sven Kivisildnik, Linnar Priimägi, Aino Pervik, Mati Unt, Contra, Fagira D. Morti, Aapo Ilves, Aarne Ruben, Juku-Kalle Raid

  19. Comparison of validity and reliability of the Migraine disability assessment (MIDAS) versus headache impact test (HIT) in an Iranian population.

    Science.gov (United States)

    Ghorbani, Abbas; Chitsaz, Ahmad

    2011-01-01

    Migraine is one of the most common headaches that affect 11% or more adult population. Recently, researchers have designed two questionnaires, namely Headache Impact Test (HIT) and Migraine Disability Assessment (MIDAS), with the aim of improving migraine care. These two tests provide a standard measurement about migraine's effects on people's life style that divide patients into 4 groups (grades) based on headaches intensity. The aim of this study was to compare the validity and reliability of these two tests. This study was designed as a multicenter, descriptive study to compare validity and reliability of Persian version of MIDAS and HIT questionnaires in 240 males and females with a migraine diagnosis according to criteria for headache and facial pain of the International Headache Society (IHS). The patients were enrolled in the study from 3 neurology clinics in Isfahan, Iran, between July 2004 and January 2005 and were evaluated at baseline (visit 1) and 4 weeks later (visit 2). According to our study, there was a high correlation between two tests (r = 0.94). This decreased their MIDAS grade in comparison to their grade HIT questionnaire. These findings demonstrated that Persian version of HIT have the same validity and reliability as MIDAS. Replying to HIT questionnaire was easier than MIDAS for Iranian patients. Physicians can reliably use the Persian translation of both MIDAS and HIT questionnaires to define the severity of illness and its treatment strategy as a self-administered report by migraine patients. However, we recommend HIT for its simplicity in headache clinics.

  20. Dansk oversættelse af MiDAS, et redskab til assessment af musikterapi for personer med demens

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Lykkegaard, Chris; McDermott, Orii

    2018-01-01

    DAS explored which procedures is used for outcome measure translation and cultural adaptation, and based on this recommended a ten-step procedure. We applied this procedure in order to translate MiDAS and hereby develop the Danish MiDAS-DK. The Danish MiDAS version has been tested by more than 20 professionals......) musikterapeuten umiddelbart efter sessionen for at vurdere forandringer i selve sessionen. Der har været stor interesse for at anvende MiDAS i flere Europæiske lande, herunder Danmark. Derfor undersøgte udviklerne af MiDAS hvilke procedurer der anvendes til oversættelse og kulturel tilpasning af...... assessmentredskaber, og anbefalede på den baggrund en ti-trins procedure. Vi anvendte denne procedure til oversættelsen af MiDAS og således udviklingen af den danske MiDAS-DK. Den danske version af MiDAS er afprøvet af mere end 20 fagpersoner på baggrund af 296 udfyldte MiDAS-skemaer. Målet med artiklen er...

  1. Swedbank ei pikenda Rumeenia fondi võlakirju / Piret Reiljan

    Index Scriptorium Estoniae

    Reiljan, Piret, 1983-

    2010-01-01

    Swedbank ei pikendanud IPC Investment Groupi poolt hallatava Rumeenia kinnisvarafondi Nord Hill Land Portfolio tähtaega ning fond peab vara müüki panema. IPC Investment Groupi omanikud on Indrek Elhi ja rumeenlane Ciprian Lopata

  2. Turundajad ei oska kasutada kogutud kliendiinfot / Eda-Liis Kann

    Index Scriptorium Estoniae

    Kann, Eda-Liis, 1979-

    2004-01-01

    Eesti kaupmehed koguvad kliendiinfot, kuid klientide kasumlikkust ei arvutata. Lisa: Kliendid pole motiveeritud oma ostu registreerima; Tesco põhilised erinevused võrreldes Eesti lojaalsusprogrammidega; Partnerkaart; Säästukaart; Stockmanni püsikliendikaart

  3. Pärt, Arvo: "Beatus". Statuit ei Dominus / Patric Wiklacz

    Index Scriptorium Estoniae

    Wiklacz, Patric

    1997-01-01

    Uuest heliplaadist "Pärt, Arvo: "Beatus". Statuit ei Dominus. Missa syllabica. Beatus Petronius. 7 Magnificat-Antiphonen. De profundis. Memento. Cantate Domino. Solfeggio. Estonian Philharmonic Chamber Choir, T. Kaljuste". Virgin Classics 545 276-2 (CD:167F)

  4. Kui parimast ei piisa, siis piisab erinevast / Gustav Hafren

    Index Scriptorium Estoniae

    Hafren, Gustav

    2003-01-01

    Autor leiab, et turul, kus ei võida mitte kvaliteetsemad tooted, vaid tooted, mis omavad kindlat kohta klientide teadvuses, on kõige olulisem eristuda konkurentidest. Lisa: Milline on kliendi teadvus? Kokkuvõte autori ettekandest turunduskonverentsil "Password 2003".

  5. "Live 8" tähti ei auhinnata

    Index Scriptorium Estoniae

    2006-01-01

    Briti muusikapreemia Brit Awards žürii ei võtnud parima kontsertesituse auhinnapretendentide nimekirja ansamblit Pink Floyd ja lauljat Robbie Williamsi, kuna nende 20-minutiline esitus polevat auhinna saamiseks veenev

  6. Uuring : neljandik elanikke ei tea Ilvese tegevusest midagi / Dannar Leitmaa

    Index Scriptorium Estoniae

    Leitmaa, Dannar, 1982-

    2007-01-01

    Uuringufirma Faktum & Ariko korraldatud küsitlusest selgus, et 23 % elanikest ei oska öelda, millega on president Toomas Hendrik Ilves viimase aasta jooksul silma paistnud. Eesti Päevalehe poolt tellitud küsitluse tulemusi kommenteerib politoloog Rein Toomla. Ilmunud ka: Harju Ekspress 16. nov. 2007, lk. 2, pealk.: Presidendi tegevusest ei tea iga neljas eestimaalane midagi (lüh.)

  7. MIDAS, prototype Multivariate Interactive Digital Analysis System, phase 1. Volume 1: System description

    Science.gov (United States)

    Kriegler, F. J.

    1974-01-01

    The MIDAS System is described as a third-generation fast multispectral recognition system able to keep pace with the large quantity and high rates of data acquisition from present and projected sensors. A principal objective of the MIDAS program is to provide a system well interfaced with the human operator and thus to obtain large overall reductions in turnaround time and significant gains in throughput. The hardware and software are described. The system contains a mini-computer to control the various high-speed processing elements in the data path, and a classifier which implements an all-digital prototype multivariate-Gaussian maximum likelihood decision algorithm operating at 200,000 pixels/sec. Sufficient hardware was developed to perform signature extraction from computer-compatible tapes, compute classifier coefficients, control the classifier operation, and diagnose operation.

  8. MIDAS and HIT-6 French translation: reliability and correlation between tests.

    Science.gov (United States)

    Magnoux, E; Freeman, M A; Zlotnik, G

    2008-01-01

    The aim was to evaluate the test-retest reliability of the French translation of the Migraine Disability Assessment (MIDAS) and Headache Impact Test (HIT)-6 questionnaires as applied to episodic and chronic headaches and to assess the correlation between these two questionnaires. The MIDAS and HIT-6 questionnaires, which assess the degree of migraine-related functional disability, are widely used in headache treatment clinics. The French translation has not been checked for test-retest reliability. MIDAS involves recall, over the previous 3 months, of the number of days with functional disability with regard to work and to home and social life. HIT-6 involves a more subjective and general assessment of headache-related disability over the previous 4 weeks. We expect that there may be greater impact recall bias for chronic headaches than for episodic headaches and considered it important to be able to determine if the reliability of these questionnaires is equally good for these two patient populations. Given that both questionnaires have the same objective, that of assessing headache impact, it was thought useful to determine if their results might show a correlation and if they could thus be used interchangeably. The study was approved by an external ethics committee. The subjects were patients who regularly visit the Clinique de la Migraine de Montréal, which specializes in the treatment of headaches. The MIDAS and HIT-6 questionnaires were completed by the patients during their regular visit. Twelve days later, the same questionnaires were mailed with a prepaid return envelope. Sixty-five patients were required in both the episodic and chronic headache groups, assuming an 80% questionnaire return rate. One hundred and eighty-five patients were enrolled, and 143 completed the study, 75 with episodic headaches and 68 with chronic headaches. The questionnaire return rate was 78.9%. On average, questionnaires were completed a second time 21 days after the first

  9. MIDAS - an atomic force microscope for in-situ imaging of cometary dust particles

    International Nuclear Information System (INIS)

    Fehringer, H.M.; Ruedenauer, F.G.; Steiger, W.

    1997-02-01

    Comets are interesting bodies, since they are considered to consist of matter remaining in essentially unchanged chemistry from the presolar nebula. Investigation of cometary matter therefore permits to draw conclusion s with respect to the composition of presolar matter. The atomic force microscope MIDAS will be the first instrument to analyze, within ESA's ROSETTA-mission priestine cometary matter in the form of dust particles emitted by comet WIRTANEN during its perihelion in 2013. Within this project, a dust model has been developed, permitting estimation of dust collection times required for statistically significant imaging of cometary particles. The dynamics of dust collection has been developed and experimental dust collection surfaces have been produced making use of modem nanostructuring techniques. Mechanical properties of 3-dimensional piezo-control elements, which are an essential part of the MIDAS microscope, have been determined. (author)

  10. MIDAS: Software for the detection and analysis of lunar impact flashes

    Science.gov (United States)

    Madiedo, José M.; Ortiz, José L.; Morales, Nicolás; Cabrera-Caño, Jesús

    2015-06-01

    Since 2009 we are running a project to identify flashes produced by the impact of meteoroids on the surface of the Moon. For this purpose we are employing small telescopes and high-sensitivity CCD video cameras. To automatically identify these events a software package called MIDAS was developed and tested. This package can also perform the photometric analysis of these flashes and estimate the value of the luminous efficiency. Besides, we have implemented in MIDAS a new method to establish which is the likely source of the meteoroids (known meteoroid stream or sporadic background). The main features of this computer program are analyzed here, and some examples of lunar impact events are presented.

  11. Anterior segment developmental anomalies in a 33-week-old fetus with MIDAS syndrome.

    Science.gov (United States)

    Herwig, Martina C; Loeffler, Karin U; Gembruch, Ulrich; Kuchelmeister, Klaus; Müller, Annette M

    2014-01-01

    We report anterior segment abnormalities in both eyes of a 33-week-old fetus endorsing the diagnosis of MIDAS (microphthalmia, dermal aplasia, and sclerocornea) syndrome. After abortion, the fetus was examined by a standard pediatric autopsy that included macroscopic and microscopic examination of both eyes. Postmortem findings included craniofacial stigmata (such as hypertelorism, a flat nose and low-set ears) and an agenesis of the corpus callosum. Array comparative genomic hybridization revealed a deletion of the short arm of the X chromosome (region Xp22.2 to p22.32). Ophthalmopathologic examination of the eyes revealed microphthalmia with anterior segment developmental anomalies, in particular sclerocornea and Peters' anomaly, respectively. General pathology findings plus the ocular findings allowed the diagnosis of MIDAS syndrome. A discussion of differential diagnoses is provided. This case report indicates that ophthalmopathologic investigation of fetal eyes can be of great value for the further classification of syndromes.

  12. Jansen-MIDAS: A multi-level photomicrograph segmentation software based on isotropic undecimated wavelets.

    Science.gov (United States)

    de Siqueira, Alexandre Fioravante; Cabrera, Flávio Camargo; Nakasuga, Wagner Massayuki; Pagamisse, Aylton; Job, Aldo Eloizo

    2018-01-01

    Image segmentation, the process of separating the elements within a picture, is frequently used for obtaining information from photomicrographs. Segmentation methods should be used with reservations, since incorrect results can mislead when interpreting regions of interest (ROI). This decreases the success rate of extra procedures. Multi-Level Starlet Segmentation (MLSS) and Multi-Level Starlet Optimal Segmentation (MLSOS) were developed to be an alternative for general segmentation tools. These methods gave rise to Jansen-MIDAS, an open-source software. A scientist can use it to obtain several segmentations of hers/his photomicrographs. It is a reliable alternative to process different types of photomicrographs: previous versions of Jansen-MIDAS were used to segment ROI in photomicrographs of two different materials, with an accuracy superior to 89%. © 2017 Wiley Periodicals, Inc.

  13. Linlane ei tea, kuidas maal elatakse / Imbi Raikna

    Index Scriptorium Estoniae

    Raikna, Imbi

    2004-01-01

    2004. a. märtsis ja aprillis tehtud uurimusest "Põllumajandusministeeriumi ja maaelu imago Eesti linnaelanike seas". Tabelid: Maakohtade külastamise sagedus; Maakohtade külastamise põhjused. Vt. ka: Mida maaelu tundjad arvavad linnaelanike uuringu tulemustest. Kommenteerivad Riigikogu liikmed Imre Sooäär, Jaanus Marrandi ja Mati Kepp, MTÜ Saaremaa Kodukant juht Elvi Viira, MTÜ Kodukant Viljandimaa juht Kaja Kaur, MTÜ Kodukant Tartumaa juht Lea Saul, Saarde vallavalitsuse volikogu esimees Väino Lill ja Lääne-Virumaa Uhtna küla elanik Inge Pikkoja

  14. MIDAS (Migraine Disability Assessment: a valuable tool for work-site identification of migraine in workers in Brazil

    Directory of Open Access Journals (Sweden)

    Yara Dadalti Fragoso

    Full Text Available CONTEXT: MIDAS was developed as a fast and efficient method for identification of migraine in need of medical evaluation and treatment. It was necessary to translate MIDAS, originally written in English, so as to apply it in Brazil and make it usable by individuals from a variety of social-economic-cultural backgrounds. OBJECTIVE: To translate and to apply MIDAS in Brazil. SETTING: Assessment of a sample of workers regularly employed by an oil refinery. SETTING: Refinaria Presidente Bernardes, Cubatão, São Paulo, Brazil. PARTICIPANTS: 404 workers of the company who correctly answered a questionnaire for the identification and evaluation of headache. When the individual considered it to be pertinent to his own needs, there was the option to answer MIDAS as well. METHODS: MIDAS, originally written in English, was translated into Brazilian Portuguese by a neurologist and by a translator specializing in medical texts. The final version of the translation was obtained when, for ten patients to whom it was applied, the text seemed clear and the results were consistent over three sessions. MAIN MEASUREMENTS: Prevalence and types of primary headaches, evaluation of MIDAS as a tool for identification of more severe cases. RESULTS: From the total of 419 questionnaires given to the employees, 404 were returned correctly completed. From these, 160 persons were identified as presenting headaches, 44 of whom considered it worthwhile answering MIDAS. Nine of these individuals who answered MIDAS were identified as severe cases of migraine due to disability caused by the condition. An interview on a later date confirmed these results. Three were cases of chronic daily headache (transformed migraine and six were cases of migraine. CONCLUSIONS: MIDAS translated to Brazilian Portuguese was a useful tool for identifying severe cases of migraine and of transformed migraine in a working environment. The workers did not consider MIDAS to be difficult to answer. Their

  15. MIDAS. An algorithm for the extraction of modal information from experimentally determined transfer functions

    International Nuclear Information System (INIS)

    Durrans, R.F.

    1978-12-01

    In order to design reactor structures to withstand the large flow and acoustic forces present it is necessary to know something of their dynamic properties. In many cases these properties cannot be predicted theoretically and it is necessary to determine them experimentally. The algorithm MIDAS (Modal Identification for the Dynamic Analysis of Structures) which has been developed at B.N.L. for extracting these structural properties from experimental data is described. (author)

  16. Construction simulation analysis of 120m continuous rigid frame bridge based on Midas Civil

    Science.gov (United States)

    Shi, Jing-xian; Ran, Zhi-hong

    2018-03-01

    In this paper, a three-dimensional finite element model of a continuous rigid frame bridge with a main span of 120m is established by the simulation and analysis of Midas Civil software. The deflection and stress of the main beam in each construction stage of continuous beam bridge are simulated and analyzed, which provides a reliable technical guarantee for the safe construction of the bridge.

  17. The nature of (sub-)micrometre cometary dust particles detected with MIDAS

    Science.gov (United States)

    Mannel, T.; Bentley, M. S.; Torkar, K.; Jeszenszky, H.; Romstedt, J.; Schmied, R.

    2015-10-01

    The MIDAS Atomic Force Microscope (AFM) onboard Rosetta collects dust particles and produces three-dimensional images with nano- to micrometre resolution. To date, several tens of particles have been detected, allowing determination of their properties at the smallest scale. The key features will be presented, including the particle size, their fragile character, and their morphology. These findings will be compared with the results of other Rosetta dust experiments.

  18. MIDAS phase II. A program for the modal analysis of structures

    International Nuclear Information System (INIS)

    Durrans, R.F.

    1980-10-01

    The application of Modal Analysis to the experimental characterisation of structures is described. A program MIDAS (Modal Identification for the Dynamic Analysis of Structures) has been developed at B.N.L. to perform this function and this report presents a full description of its use. The structures within the coolant circuits of nuclear reactors must be designed to withstand large flow and acoustic forces. (U.K.)

  19. Transcriptome characterization of the South African abalone Haliotis midae using sequencing-by-synthesis

    Directory of Open Access Journals (Sweden)

    Roodt-Wilding Rouvay

    2011-03-01

    Full Text Available Abstract Background Worldwide, the genus Haliotis is represented by 56 extant species and several of these are commercially cultured. Among the six abalone species found in South Africa, Haliotis midae is the only aquacultured species. Despite its economic importance, genomic sequence resources for H. midae, and for abalone in general, are still scarce. Next generation sequencing technologies provide a fast and efficient tool to generate large sequence collections that can be used to characterize the transcriptome and identify expressed genes associated with economically important traits like growth and disease resistance. Results More than 25 million short reads generated by the Illumina Genome Analyzer were de novo assembled in 22,761 contigs with an average size of 260 bp. With a stringent E-value threshold of 10-10, 3,841 contigs (16.8% had a BLAST homologous match against the Genbank non-redundant (NR protein database. Most of these sequences were annotated using the gene ontology (GO and eukaryotic orthologous groups of proteins (KOG databases and assigned to various functional categories. According to annotation results, many gene families involved in immune response were identified. Thousands of simple sequence repeats (SSR and single nucleotide polymorphisms (SNP were detected. Setting stringent parameters to ensure a high probability of amplification, 420 primer pairs in 181 contigs containing SSR loci were designed. Conclusion This data represents the most comprehensive genomic resource for the South African abalone H. midae to date. The amount of assembled sequences demonstrated the utility of the Illumina sequencing technology in the transcriptome characterization of a non-model species. It allowed the development of several markers and the identification of promising candidate genes for future studies on population and functional genomics in H. midae and in other abalone species.

  20. Distinct roles of beta1 metal ion-dependent adhesion site (MIDAS), adjacent to MIDAS (ADMIDAS), and ligand-associated metal-binding site (LIMBS) cation-binding sites in ligand recognition by integrin alpha2beta1.

    Science.gov (United States)

    Valdramidou, Dimitra; Humphries, Martin J; Mould, A Paul

    2008-11-21

    Integrin-ligand interactions are regulated in a complex manner by divalent cations, and previous studies have identified ligand-competent, stimulatory, and inhibitory cation-binding sites. In collagen-binding integrins, such as alpha2beta1, ligand recognition takes place exclusively at the alpha subunit I domain. However, activation of the alphaI domain depends on its interaction with a structurally similar domain in the beta subunit known as the I-like or betaI domain. The top face of the betaI domain contains three cation-binding sites: the metal-ion dependent adhesion site (MIDAS), the ADMIDAS (adjacent to MIDAS), and LIMBS (ligand-associated metal-binding site). The role of these sites in controlling ligand binding to the alphaI domain has yet to be elucidated. Mutation of the MIDAS or LIMBS completely blocked collagen binding to alpha2beta1; in contrast mutation of the ADMIDAS reduced ligand recognition but this effect could be overcome by the activating monoclonal antibody TS2/16. Hence, the MIDAS and LIMBS appear to be essential for the interaction between alphaI and betaI, whereas occupancy of the ADMIDAS has an allosteric effect on the conformation of betaI. An activating mutation in the alpha2 I domain partially restored ligand binding to the MIDAS and LIMBS mutants. Analysis of the effects of Ca(2+), Mg(2+), and Mn(2+) on ligand binding to these mutants showed that the MIDAS is a ligand-competent site through which Mn(2+) stimulates ligand binding, whereas the LIMBS is a stimulatory Ca(2+)-binding site, occupancy of which increases the affinity of Mg(2+) for the MIDAS.

  1. Cometary dust at the smallest scale - latest results of the MIDAS Atomic Force Microscope onboard Rosetta

    Science.gov (United States)

    Bentley, Mark; Torkar, Klaus; Jeszenszky, Harald; Romstedt, Jens; Schmied, Roland; Mannel, Thurid

    2015-04-01

    The MIDAS instrument onboard the Rosetta orbit is a unique combination of a dust collection and handling system and a high resolution Atomic Force Microscope (AFM). By building three-dimensional images of the dust particle topography, MIDAS addresses a range of fundamental questions in Solar System and cometary science. The first few months of dust collection and scanning revealed a deficit of smaller (micron and below) particles but eventually several 10 µm-class grains were discovered. In fact these were unexpectedly large and close to the limit of what is observable with MIDAS. As a result the sharp tip used by the AFM struck the particles from the side, causing particle breakage and distortion. Analyses so far suggest that the collected particles are fluffy aggregates of smaller sub-units, although determination of the size of these sub-units and high resolution re-imaging remains to be done. The latest findings will be presented here, including a description of the particles collected and the implications of these observations for cometary science and the Rosetta mission at comet 67P.

  2. Ground truth of (sub-)micrometre cometary dust - Results of MIDAS onboard Rosetta

    Science.gov (United States)

    Mannel, Thurid; Bentley, Mark; Schmied, Roland; Torkar, Klaus; Jeszenszky, Harald; Romsted, Jens; Levasseur-Regourd, A.; Weber, Iris; Jessberger, Elmar K.; Ehrenfreund, Pascale; Köberl, Christian; Havnes, Ove

    2016-10-01

    The investigation of comet 67P by Rosetta has allowed the comprehensive characterisation of pristine cometary dust particles ejected from the nucleus. Flying alongside the comet at distances as small as a few kilometres, and with a relative velocity of only centimetres per second, the Rosetta payload sampled almost unaltered dust. A key instrument to study this dust was MIDAS (the Micro-Imaging Dust Analysis System), a dedicated atomic force microscope that scanned the surfaces of hundreds of (sub-)micrometre sized particles in 3D with resolutions down to nanometres. This offers the unique opportunity to explore the morphology of smallest cometary dust and expand our current knowledge about cometary material.Here we give an overview of dust collected and analysed by MIDAS and highlight its most important features. These include the ubiquitous agglomerate nature of the dust, which is found at all size scales from the largest (>10 µm) through to the smallest (MIDAS resemble primitive interplanetary dust which is a strong argument for a common cometary origin.

  3. Reconstruction of extensive air showers using the MIDAS molecular Bremsstrahlung detector

    International Nuclear Information System (INIS)

    Castro, Andre Ramos de; Bonifazi, Carla; Santos, Edivaldo Moura; Soares, Elvis do Amaral; Mello Neto, Joao Ramos Torres de; Almeida, Rogerio Menezes de

    2011-01-01

    Full text: The weakly ionized plasma created in the atmosphere after the passage of an Extensive Air Shower (EAS) gives rise to the emission of continuous radiation known as Molecular Bremsstrahlung Radiation (MBR) as free electrons scatter off neutral nitrogen (and less frequently oxygen) molecules. The isotropic and unpolarized nature of MBR rises the possibility of an EAS detection similar to that using fluorescence telescopes to capture the ultraviolet light emitted by the ionized nitrogen molecules. The MBR emission, however, falls into the centimeter wavelength range, requiring the use of radio/microwave antennas instead of optical telescopes. In order to test the feasibility of the technique, the MIDAS (Microwave Detection of Air Showers) Collaboration has built a prototype detector where a parabolical reflector illuminates a multi-pixel camera of commercial TV satellite C-band (3.4-4.2 GHz) feeds. This work addresses the geometrical reconstruction of EAS induced by Ultra High Energy Cosmic Rays (UHECR) using the MIDAS detector. The reconstruction chain is similar to that currently applied to the Auger Fluorescence detector events. We have simulated the shower MBR emission assuming two different scenarios: coherent and incoherent emission, i.e., radiation intensity scaling quadratically and linearly with the energy of the primary particle. The MIDAS prototype detector's response is then simulated. Finally, given the simulated events in real data format, we reconstruct the shower's arrival direction, including direction uncertainties and estimate the expected rate of observed events. (author)

  4. Sangpomm ei taha lahkuda ehk uuenduslikkust tuleb üritusturundusse visalt / Olavi Andla

    Index Scriptorium Estoniae

    Andla, Olavi, 1970-

    2013-01-01

    Firma suvepäevade korraldamisest, kuhu tehnoloogia kasutamine toob uudseid lahendusi. Lähemalt kahest ürituse formaadist - Action Track ja Amazing Race, mida saab kasutada seiklusmängude korraldamisel

  5. Ryanair ei kavatse toetada ebaefektiivset lennujaama / Benny Berger ; interv. Henrik Aavik

    Index Scriptorium Estoniae

    Berger, Benny

    2007-01-01

    Ryanairi uute sihtkohtade direktor Benny Berger leiab, et suurim takistus Eestisse lendamisel on hind, mida Tallinna lennujaam neilt küsib. Diagramm: Ryanairi tulek lööks Tallinnas turu sassi. Kommenteerib Oleg Harlamov

  6. Effects of midas® on nematodes in commercial floriculture production in Florida.

    Science.gov (United States)

    Kokalis-Burelle, Nancy; Rosskopf, Erin N; Albano, Joseph P; Holzinger, John

    2010-03-01

    Cut flower producers currently have limited options for nematode control. Four field trials were conducted in 2006 and 2007 to evaluate Midas® (iodomethane:chloropicrin 50:50) for control of root-knot nematodes (Meloidogyne arenaria) on Celosia argentea var. cristata in a commercial floriculture production field in southeastern Florida. Midas (224 kg/ha) was compared to methyl bromide:chloropicrin (98:2, 224 kg/ha), and an untreated control. Treatments were evaluated for effects on Meloidogyne arenaria J2 and free-living nematodes in soil through each season, and roots at the end of each season. Plant growth and root disease were also assessed. Population levels of nematodes isolated from soil were highly variable in all trials early in the season, and generally rebounded by harvest, sometimes to higher levels in fumigant treatments than in the untreated control. Although population levels of nematodes in soil were not significantly reduced during the growing season, nematodes in roots and galling at the end of the season were consistently reduced with both methyl bromide and Midas compared to the untreated control. Symptoms of phytotoxicity were observed in Midas treatments during the first year and were attributed to Fe toxicity. Fertilization was adjusted during the second year to investigate potential fumigant/fertilizer interactions. Interactions occurred at the end of the fourth trial between methyl bromide and fertilizers with respect to root-knot nematode J2 isolated from roots and galling. Fewer J2 were isolated from roots treated with a higher level of Fe (3.05%) in the form of Fe sucrate, and galling was reduced in methyl bromide treated plots treated with this fertilizer compared to Fe EDTA. Reduced galling was also seen with Midas in Fe sucrate fertilized plots compared to Fe EDTA. This research demonstrates the difficulty of reducing high root-knot nematode population levels in soil in subtropical conditions in production fields that have been

  7. Preliminary Study on the Development of MIDAS/GCR to Simulate the Plate-out Phenomena from a HTGR

    International Nuclear Information System (INIS)

    Park, Jong-Hwa; Kim, Dong-Ha; Lee, Won-Jae

    2006-01-01

    In HTGR, the dominant removal mechanism of the condensable fission product gas is a 'plate-out' on various kinds of surfaces over the primary coolant loop. The plate-outs are complex phenomena that are dependent on the mass transfer rate from the coolant to the fixed surface, the adsorption and desorption of the gas fission product, the material of the surfaces, the operation temperature, the fission product species, etc. In a normal operation, the important information on a plate-out is the amount and the distribution and the type of isotope. This information is applied to construct a safety engineering system, to calculate the necessary shielding and to estimate the impact on the environment. The status of a model development and available data are performed extensively but the data still has a large uncertainty. The objective of this study is to compare the condensation model of a gas fission product in the MIDAS for a PWR with the PADLOC model for a HTGR developed by GA and to perform a feasibility calculation on OGL-1 with MIDAS. The results of the model review on MIDAS and PADLOC, the feasibility calculation results on OGL-1 with MIDAS and the phenomena to be implemented into MIDAS to simulate the plate-out phenomena from HTGR are identified and listed

  8. Dansk oversættelse af MiDAS, et redskab til assessment af musikterapi for personer med demens

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Lykkegaard, Chris; McDermott, Orii

    2018-01-01

    Music in Dementia Assessment Scales, MiDAS, er udviklet til at vurdere ændringer i trivsel hos borgere med demens som har deltaget i musikterapi. Målingen udføres af 1) personale før og efter musikterapien for at vurdere om der er en indflydelse i hverdagssituationer efterfølgende, eller af 2......) musikterapeuten umiddelbart efter sessionen for at vurdere forandringer i selve sessionen. Der har været stor interesse for at anvende MiDAS i flere Europæiske lande, herunder Danmark. Derfor undersøgte udviklerne af MiDAS hvilke procedurer der anvendes til oversættelse og kulturel tilpasning af...... assessmentredskaber, og anbefalede på den baggrund en ti-trins procedure. Vi anvendte denne procedure til oversættelsen af MiDAS og således udviklingen af den danske MiDAS-DK. Den danske version af MiDAS er afprøvet af mere end 20 fagpersoner på baggrund af 296 udfyldte MiDAS-skemaer. Målet med artiklen er...

  9. A User's Guide to the SNF ampersand INEL EIS

    International Nuclear Information System (INIS)

    1995-01-01

    This User's Guide is intended to help you find information in the SNF and INEL EIS (that's short for US Department of Energy Programmatic Spent Nuclear Fuel Management and Idaho National Engineering Laboratory Environmental Restoration and Waste Management Programs Final Environmental Impact Statement). The first section of this Guide gives you a brief overview of the SNF ampersand INEL EIS., The second section is organized to help you find specific information in the Environmental Impact Statement -- whether you're interested in a management alternative, a particular site (such as Hanford), or a discipline (such as land use or water quality)

  10. Snap clutch, a moded approach to solving the Midas touch problem.

    OpenAIRE

    Istance, Howell; Bates, R.; Hyrskykari, A.; Vickers, Stephen

    2008-01-01

    This paper proposes a simple approach to an old problem, that of the 'Midas Touch'. This uses modes to enable different types of mouse behavior to be emulated with gaze and by using gestures to switch between these modes. A light weight gesture is also used to switch gaze control off when it is not needed, thereby removing a major cause of the problem. The ideas have been trialed in Second Life, which is characterized by a feature-rich of set of interaction techniques and a 3D graphical world...

  11. An Integration of the Restructured Melcor for the Midas Computer Code

    International Nuclear Information System (INIS)

    Sunhee Park; Dong Ha Kim; Ko-Ryu Kim; Song-Won Cho

    2006-01-01

    The developmental need for a localized severe accident analysis code is on the rise. KAERI is developing a severe accident code called MIDAS, which is based on MELCOR. In order to develop the localized code (MIDAS) which simulates a severe accident in a nuclear power plant, the existing data structure is reconstructed for all the packages in MELCOR, which uses pointer variables for data transfer between the packages. During this process, new features in FORTRAN90 such as a dynamic allocation are used for an improved data saving and transferring method. Hence the readability, maintainability and portability of the MIDAS code have been enhanced. After the package-wise restructuring, the newly converted packages are integrated together. Depending on the data usage in the package, two types of packages can be defined: some use their own data within the package (let's call them independent packages) and the others share their data with other packages (dependent packages). For the independent packages, the integration process is simple to link the already converted packages together. That is, the package-wise structuring does not require further conversion of variables for the integration process. For the dependent packages, extra conversion is necessary to link them together. As the package-wise restructuring converts only the corresponding package's variables, other variables defined from other packages are not touched and remain as it is. These variables are to be converted into the new types of variables simultaneously as well as the main variables in the corresponding package. Then these dependent packages are ready for integration. In order to check whether the integration process is working well, the results from the integrated version are verified against the package-wise restructured results. Steady state runs and station blackout sequences are tested and the major variables are found to be the same each other. In order to verify the results, the integrated

  12. The collection and analysis of transient test data using the mobile instrumentation data acquisition system (MIDAS)

    International Nuclear Information System (INIS)

    Uncapher, W.L.; Arviso, M.

    1995-01-01

    Packages designed to transport radioactive materials are required to survive exposure to environments defined in Code of Federal Regulations. Cask designers can investigate package designs through structural and thermal testing of full-scale packages, components, or representative models. The acquisition of reliable response data from instrumentation measurement devices is an essential part of this testing activity. Sandia National Laboratories, under the sponsorship of the US Department of Energy (DOE), has developed the Mobile Instrumentation Data Acquisition System (MIDAS) dedicated to the collection and processing of structural and thermal data from regulatory tests

  13. The MIDAS touch for Accurately Predicting the Stress-Strain Behavior of Tantalum

    Energy Technology Data Exchange (ETDEWEB)

    Jorgensen, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-03-02

    Testing the behavior of metals in extreme environments is not always feasible, so material scientists use models to try and predict the behavior. To achieve accurate results it is necessary to use the appropriate model and material-specific parameters. This research evaluated the performance of six material models available in the MIDAS database [1] to determine at which temperatures and strain-rates they perform best, and to determine to which experimental data their parameters were optimized. Additionally, parameters were optimized for the Johnson-Cook model using experimental data from Lassila et al [2].

  14. Balti riikide vabadus ei ohusta Venemaad / Daniel Fried

    Index Scriptorium Estoniae

    Fried, Daniel, 1952-

    2007-01-01

    Ilmunud ka: The Baltic Times, 21. juuni 2007, lk. 15. Ameerika Ühendriikide asevälisminister Euroopa ja Euraasia asjus Daniel Fried Balti riikide tunnustamisest, vabadusest ja suveräänsusest. Venemaa huvides on olla ümbritsetud rahulikest ja jõukatest demokraatiatest, ähvardustele ja sanktsioonidele ei tohi jätta ruumi

  15. Emotional intelligence (EI) and nursing leadership styles among nurse managers.

    Science.gov (United States)

    Tyczkowski, Brenda; Vandenhouten, Christine; Reilly, Janet; Bansal, Gaurav; Kubsch, Sylvia M; Jakkola, Raelynn

    2015-01-01

    Less than 12.5% of nurses aspire to leadership roles, noting lack of support and stress as major factors in their decision not to pursue this area of practice. Psychological resiliency, described as the ability to properly adapt to stress and adversity, is key to successful nurse managers. Emotional intelligence (EI) is a related concept to resiliency and is another noteworthy predictor of leadership and management success. This study was undertaken to determine the level of and relationship between EI and leadership style of nurse managers employed in Wisconsin and Illinois facilities. A descriptive, exploratory study design was utilized, with a convenience sample of nurse managers working in 6 large Midwestern health systems. Nurse managers were invited to participate in the study by their employer, completing the online consent form and the demographic, Multifactor Leadership Questionnaire (MLQ) Form 5X and the Emotional Quotient Inventory (EQ-i 2.0) surveys. Statistically significant positive relationships were noted between EI and transformational leadership and the outcomes of leadership (extra effort, effectiveness, and satisfaction). No statistically significant relationships were noted between EI and transactional or laissez-faire leadership styles.

  16. Turvalisust ei taga vaid sinine vilkur / Ken-Marti Vaher

    Index Scriptorium Estoniae

    Vaher, Ken-Marti, 1974-

    2005-01-01

    Kuritegevuse vastasest võitlusest. Sama ka Pärnu Postimees 8. juuni 2005, lk. 15 ; Hiiu Leht 10. juuni 2005, lk. 2 ; Vali Uudised 8. juuni 2005, lk. 2 artiklis pealkiri kujul: Turvalisust ei taga ainuüksi sinine vilkur ; Nädaline 14. juuni 2005, lk. 4 ; Koit 14. juuni 2005, lk. 6 ; Valgamaalane 5. juuli 2005, lk. 2

  17. Somaalia piraadid ei taha Saksamaale minna / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2010-01-01

    Saksa kaubalaeva Taipan kaaperdamiselt tabatud somaallased ei taha, et neid antaks välja Saksamaale. Siiani on suurem osa tabatud Somaalia piraatidest saadetud Kenya kohtutesse. Rotterdamis algab järgmisel nädalal üle mitme sajandi esimene Euroopa piraadiprotsess

  18. Maksuamet ei välista Concordia pankrotti / Alo Lõhmus

    Index Scriptorium Estoniae

    Lõhmus, Alo

    2003-01-01

    Maksuamet nendib, et kui Concordia ülikool ei tule toime oma võlgade maksmisega esmaspäevaks, võib kõne alla tulla ka kooli pankroti algatamine. Eesti Üliõpilaskondade Liit ja Concordia Ülikooli Eesis Üliõpilasesindus korraldavad Concordia probleeme käsitleva konverentsi "Kes vastutab Concordia tudengite eest?"

  19. Eesti valitsuse argumendid ei pea vett / Indrek Veiserik

    Index Scriptorium Estoniae

    Veiserik, Indrek

    2008-01-01

    Autori väitel püsib Iraak lõhestatuna ja mingit rahvuslikku leppimist ei ole seal toimunud, seetõttu on Eesti valitsuse loodud ettekujutus peatsest rahu saabumisest vale. USA nädalalehe Newsweek kolumnist Fareed Zakaria leiab, et USA jaoks oleks mõistlik strateegia Iraagis luua rahvusvaheliste institutsioonide poolt sanktsioneeritud rahutagamismissioon

  20. Natura 2000 ei lõpeta elu maal / Aleksei Lotman

    Index Scriptorium Estoniae

    Lotman, Aleksei, 1960-

    2004-01-01

    Natura alade kaitsekorralduse alused sätestab loodusdirektiivi paragrahv 6. Selle põhimõte on vältida elupaikade kahjustamist Natura aladel. Mingi ala kandmine Natura 2000 võrgustikku ei tähenda sugugi igasuguse inimtegevuse automaatset keelamist

  1. Pärnu ATP ei usu streigisse / Tõnu Kann

    Index Scriptorium Estoniae

    Kann, Tõnu, 1957-

    2004-01-01

    Eesti transpordi- ja teetöötajate ametiühing ähvardab uuest aastast üldstreigiga, kui autoettevõtjate liit ei allkirjasta uut üldtöökokkulepet, mis tõstaks tööliste tunnipalga alammäära kuni 150 protsenti. Arvamust avaldab Pärnu bussipargi direktor Andrus Kärpuk

  2. Suitsetamisega võitlemisel ei aita inimeste kiusamine / Silver Meikar

    Index Scriptorium Estoniae

    Meikar, Silver, 1978-

    2004-01-01

    Suitsetamise vastu võitlemisel ei tohiks kasutada rangelt seadusi vaid võimaldada soodsalt osta suitsetamisvastaseid vahendeid, leiab autor. Vt. ka: Silver Meikar: Olen valmis hoidma Eesti edu; Silver Meikar saatis lugejakirja Saksamaa päevalehtedele; Arvamusi Silver Meikarist; Silver Meikar loobus paberkandjale trükitud seaduseelnõudest

  3. Utilization Status of Electronic Information Sources (EIS) for HIV ...

    African Journals Online (AJOL)

    Tesfa

    HIV/AIDS Care and Treatment in Specialized Teaching Hospitals of. Ethiopia, 2016. Senait Samuel Bramo. 1. , Tesfamichael Alaro Agago. 2*. OPEN ACCESS. Citation: Senait Samuel Bramo,. Tesfamichael Alaro Agago. Utilization. Status of Electronic Information Sources. (EIS) for HIV/AIDS Care and Treatment.

  4. EI2N 2009 PC Co-chairs' Message

    Science.gov (United States)

    Panetto, Hervé; Bernus, Peter; Gonçalves, Ricardo; Goranson, Ted

    After the successful third edition in 2008, the fourth edition of the Enterprise Integration, Interoperability and Networking workshop (EI2N 2009) was organized as part of the OTM 2009 Federated Conferences and was supported by the IFAC Technical Committee 5.3 "Enterprise Integration and Networking" and the IFIP Working Group 5.12 "Architectures for Enterprise Integration."

  5. Maestro ei või õnneta elada / Silja Joon

    Index Scriptorium Estoniae

    Joon, Silja, 1966-

    2005-01-01

    Helilooja Veljo Tormise 75. aasta juubelikontserdist "Ei või õnneta elada" 13. aug. Pärnu kontserdimajas (korraldaja Ave Sopp), helilooja palvest õnnitlemiseks mõeldud lillede ja kingituste raha temanimelisse rahvusliku koorimuusika väärtustamiseks loodud fondi kandmisest

  6. Linnugripp ei ole biorelv / Kevin Probert-Ehaver

    Index Scriptorium Estoniae

    Probert-Ehaver, Kevin

    2008-01-01

    Vastukaja 10. juulil Eesti Ekspressis ilmunud artiklile "Linnugripp - surm katseklaasist", milles väidetakse, et linnugripp ning teised uued nakkushaigused on biorelvad. Kriisireguleerimise konsultant selgitab, et nii Eesti kui ka Ameerika spetsialistide hinnangul ei ole linnugripp kuidagi seotud biorelvade programmiga

  7. A restructuring of the CF/EDF packages for the MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S.H.; Kim, K.R.; Kim, D.H.

    2004-01-01

    The CF and EDF packages, which allow the user to define the functions of variables in a database and the usage of an external data file, have been restructured for the MIDAS computer code. MIDAS is being developed as an integrated severe accident analysis code with a user-friendly graphical user interface and a modernized data structure. To restructure the code, the data transferring methods of the current MELCOR code are modified and then partially adopted into the CF/EDF packages. The data structure of the current MELCOR code using FORTRAN77 has a difficulty in grasping the meaning of the variables as pointers are used to define their addresses. New features of FORTRAN90 make it possible to allocate the storage dynamically and to use the user-defined data type without pointers leading to an efficient memory treatment and an easy understanding of the code. Restructuring of the CF/EDF packages addressed in this paper includes a module development and subroutine modification. The verification has been done by comparing the results of the modified code with those of the existing code and the trends are almost the same to each other. Therefore the similar approach could be extended to the entire code package for code restructuring. It is expected that the code restructuring will accelerate the code's domestication thanks to a direct understanding of each variable and an easy implementation of the modified or newly developed models. (author)

  8. Measuring surface salinity in the N. Atlantic subtropical gyre. The SPURS-MIDAS cruise, spring 2013

    Science.gov (United States)

    Font, Jordi; Ward, Brian; Emelianov, Mikhail; Morisset, Simon; Salvador, Joaquin; Busecke, Julius

    2014-05-01

    SPURS-MIDAS (March-April 2013) on board the Spanish R/V Sarmiento de Gamboa was a contribution to SPURS (Salinity Processes in the Upper ocean Regional Study) focused on the processes responsible for the formation and maintenance of the salinity maximum associated to the North Atlantic subtropical gyre. Scientists from Spain, Ireland, France and US sampled the mesoscale and submesoscale structures in the surface layer (fixed points and towed undulating CTD, underway near surface TSG) and deployed operational and experimental drifters and vertical profilers, plus additional ocean and atmospheric data collection. Validation of salinity maps obtained from the SMOS satellite was one of the objectives of the cruise. The cruise included a joint workplan and coordinated sampling with the US R/V Endeavor, with contribution from SPURS teams on land in real time data and analysis exchange. We present here an overview of the different kinds of measurements made during the cruise, as well as a first comparison between SMOS-derived sea surface salinity products and salinity maps obtained from near-surface sampling in the SPURS-MIDAS area and from surface drifters released during the cruise.

  9. Application of the MIDAS approach for analysis of lysine acetylation sites.

    Science.gov (United States)

    Evans, Caroline A; Griffiths, John R; Unwin, Richard D; Whetton, Anthony D; Corfe, Bernard M

    2013-01-01

    Multiple Reaction Monitoring Initiated Detection and Sequencing (MIDAS™) is a mass spectrometry-based technique for the detection and characterization of specific post-translational modifications (Unwin et al. 4:1134-1144, 2005), for example acetylated lysine residues (Griffiths et al. 18:1423-1428, 2007). The MIDAS™ technique has application for discovery and analysis of acetylation sites. It is a hypothesis-driven approach that requires a priori knowledge of the primary sequence of the target protein and a proteolytic digest of this protein. MIDAS essentially performs a targeted search for the presence of modified, for example acetylated, peptides. The detection is based on the combination of the predicted molecular weight (measured as mass-charge ratio) of the acetylated proteolytic peptide and a diagnostic fragment (product ion of m/z 126.1), which is generated by specific fragmentation of acetylated peptides during collision induced dissociation performed in tandem mass spectrometry (MS) analysis. Sequence information is subsequently obtained which enables acetylation site assignment. The technique of MIDAS was later trademarked by ABSciex for targeted protein analysis where an MRM scan is combined with full MS/MS product ion scan to enable sequence confirmation.

  10. The development of Music in Dementia Assessment Scales (MiDAS).

    Science.gov (United States)

    McDermott, Orii; Orrell, Martin; Ridder, Hanne Mette

    2015-07-03

    There is a need to develop an outcome measure specific to music therapy in dementia that reflects a holistic picture of the therapy process and outcome. This study aimed to develop a clinically relevant and scientifically robust music therapy outcome measure incorporating the values and views of people with dementia. Focus groups and interviews were conducted to obtain qualitative data on what music meant to people with dementia and the observed effects of music. Expert and peer consultations were conducted at each stage of the measure development to maximise its content validity. The new measure was field-tested by clinicians in a care home. Feedback from the clinicians and music therapy experts were incorporated during the review and refinement process of the measure. A review of the existing literature, the experiential results and the consensus process enabled the development of the new outcome measure "Music in Dementia Assessment Scales (MiDAS)". Analysis of the qualitative data identified five key areas of the impact of music on people with dementia and they were transformed as the five Visual Analogue Scale (VAS) items: levels of Interest, Response, Initiation, Involvement and Enjoyment. MiDAS comprises the five VAS items and a supplementary checklist of notable positive and negative reactions from the individual. This study demonstrates that it is possible to design and develop an easy to apply and rigorous quantitative outcome measure which has a high level of clinical relevance for people with dementia, care home staff and music therapists.

  11. A Restructuring of the CAV and FDI Package for the MIDAS Computer Code

    International Nuclear Information System (INIS)

    Park, S. H.; Kim, D. H.; Cho, S. W.

    2006-01-01

    As one of the processes for a localized severe accident analysis code, KAERI is developing a severe accident code MIDAS. The MIDAS code is being developed based on MELCOR. The existing data saving method of MELCOR uses pointer variables for a fix-sized storage management, and it deteriorates the readability, maintainability and portability of the code. As a most important process for a localized severe accident analysis code, it is needed convenient method for data handling. So, it has been used the new features in FORTRAN90 such as a dynamic allocation for the restructuring. The restructuring of the data saving and transferring method of the existing code makes it easy to understand the code. Before an entire restructuring of the code, a restructuring template for a simple package was developed and tested. The target for the restructuring in this paper was the CAV and FDI packages. The CAV(cavity) package is responsible for modeling the attack on the basement concrete by hot core materials. The FDI(Fuel Dispersal Interactions) package is responsible for modeling both low and high pressure molten fuel ejection from the RPV into the reactor cavity, control volumes and surfaces. The verification was done through comparing the results before and after the restructuring

  12. Molecular Ionization-Desorption Analysis Source (MIDAS) for Mass Spectrometry: Thin-Layer Chromatography

    Science.gov (United States)

    Winter, Gregory T.; Wilhide, Joshua A.; LaCourse, William R.

    2016-02-01

    Molecular ionization-desorption analysis source (MIDAS), which is a desorption atmospheric pressure chemical ionization (DAPCI) type source, for mass spectrometry has been developed as a multi-functional platform for the direct sampling of surfaces. In this article, its utility for the analysis of thin-layer chromatography (TLC) plates is highlighted. Amino acids, which are difficult to visualize without staining reagents or charring, were detected and identified directly from a TLC plate. To demonstrate the full potential of MIDAS, all active ingredients from an analgesic tablet, separated on a TLC plate, were successfully detected using both positive and negative ion modes. The identity of each of the compounds was confirmed from their mass spectra and compared against standards. Post separation, the chemical signal (blue permanent marker) as reference marks placed at the origin and solvent front were used to calculate retention factor (Rf) values from the resulting ion chromatogram. The quantitative capabilities of the device were exhibited by scanning caffeine spots on a TLC plate of increasing sample amount. A linear curve based on peak are, R2 = 0.994, was generated for seven spots ranging from 50 to 1000 ng of caffeine per spot.

  13. UPTF test 21D counterpart test in the MIDAS test facility

    International Nuclear Information System (INIS)

    Yoon, B. C.; Ah, D. J.; Joo, I. C.; Kwon, T. S.; Park, W. M.; Song, C. H.

    2002-01-01

    This paper describes the experimental results of UPTF Test 21D counterpart tests in the downcomer during the late reflood phase of LBLOCA. The experiments have been performed in the MIDAS test facility using superheated steam and water. The test condition was determined,based on the test results of UPTF Test 21D, by applying the 'modified linear scaling method of 1/4.077 length scale. The tests of ECC direct bypass and void height are performed separately to estimate each phenomena quantitatively. The tests were carried out by varying the injection steam flow rate of intact cold legs widely to investigate the effect of steam flow rate on the direct bypass fraction and void height. In the tests, separate effect tests have been performed in cases of DVI-1,DVI- 2 and DVI-1 and 2 injections to see the direct bypass fraction according to the DVI nozzle combination. From the tests, we found that the fraction of direct ECC bypass and the void height observed in the MIDAS test facility reasonably well agree with those of UPTF test 21- D. It confirms that the applied 'modified linear scaling law' reproduces major thermal hydraulics phenomena in the downcomer during the LBLOCA reflood phase

  14. A Turkish version of myocardial infarction dimensional assessment scale (TR-MIDAS): reliability-validity assesment.

    Science.gov (United States)

    Uysal, Hilal; Ozcan, Şeyda

    2011-06-01

    Many new measuring devices have been developed so that broader psychometric measurements in the coronary artery disease, disease-specific health status measurements, and identification of the broader quality of life can be performed in the recent years. The study was intended to determine whether, and to what extent, MIDAS is a valid and reliable measurement to the patients suffering from myocardial infarction for the first time in Turkey. The research was conducted with the patients hospitalized and treated with myocardial infarction in the cardiology departments of 2 hospitals in Istanbul, Turkey, between 2007 and 2008. Psychometric evaluations of TR-MIDAS were used for validity studies; language validity, content validity, construct validity were examined. For reliability studies; the tool's internal consistency reliability, Cronbach's alpha reliability coefficient, and test-retest reliability were completed. The instrument's content validity index was determined to be "0.95". Principal component analysis revealed six factors with an eigenvalue >1.5. Cronbach's alpha was found to be 0.89 for total scale which was an acceptable value. The total's test-retest reliability was 0.51 (p<0.01). Data obtained at the end of the study supports that Turkish Myocardial Infarction Dimensional Assessment Scale is a valid and reliable instrument as a disease-specific scale to assess the patients' quality of life suffering from myocardial infarction in Turkey. Copyright © 2010 European Society of Cardiology. Published by Elsevier B.V. All rights reserved.

  15. MIDAS: Automated Approach to Design Microwave Integrated Inductors and Transformers on Silicon

    Directory of Open Access Journals (Sweden)

    L. Aluigi

    2013-09-01

    Full Text Available The design of modern radiofrequency integrated circuits on silicon operating at microwave and millimeter-waves requires the integration of several spiral inductors and transformers that are not commonly available in the process design-kits of the technologies. In this work we present an auxiliary CAD tool for Microwave Inductor (and transformer Design Automation on Silicon (MIDAS that exploits commercial simulators and allows the implementation of an automatic design flow, including three-dimensional layout editing and electromagnetic simulations. In detail, MIDAS allows the designer to derive a preliminary sizing of the inductor (transformer on the bases of the design entries (specifications. It draws the inductor (transformer layers for the specific process design kit, including vias and underpasses, with or without patterned ground shield, and launches the electromagnetic simulations, achieving effective design automation with respect to the traditional design flow for RFICs. With the present software suite the complete design time is reduced significantly (typically 1 hour on a PC based on Intel® Pentium® Dual 1.80GHz CPU with 2-GB RAM. Afterwards both the device equivalent circuit and the layout are ready to be imported in the Cadence environment.

  16. A restructuring of the MELCOR fission product packages for the MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S.H.; Kim, K.R.; Kim, D.H.

    2004-01-01

    The RN1/RN2 packages, which are the fission product-related packages in MELCOR, have been restructured for the MIDAS computer code. MIDAS is being developed as an integrated severe accident analysis code with a user-friendly graphical user interface and a modernized data structure. To do this, the data transferring methods of the current MELCOR code are modified and adopted into the RN1/RN2 package. The data structure of the current MELCOR code using FORTRAN77 has a difficulty in grasping the meaning of the variables as well as waste of memory. New features of FORTRAN90 make it possible to allocate the storage dynamically and to user-defined data type, which leads to an efficient memory treatment and an easy understanding of the code. Restructuring of the RN1/RN2 package addressed in this paper includes a module development, subroutine modification, and the treatment of MELGEN, which generates the data file, as well as MELCOR, which is processing the calculation. The verification has been done by comparing the results of the modified code with those of the existing code. As the trends are similar to each other, it implies that the same approach could be extended to the entire code package. It is expected that the code restructuring will accelerate the code domestication thanks to a direct understanding of each variable and an easy implementation of the modified or newly developed models. (author)

  17. Not a simple case - A first comprehensive phylogenetic hypothesis for the Midas cichlid complex in Nicaragua (Teleostei: Cichlidae: Amphilophus).

    Science.gov (United States)

    Geiger, Matthias F; McCrary, Jeffrey K; Schliewen, Ulrich K

    2010-09-01

    Nicaraguan Midas cichlids from crater lakes have recently attracted attention as potential model systems for speciation research, but no attempt has been made to comprehensively reconstruct phylogenetic relationships of this highly diverse and recently evolved species complex. We present a first AFLP (2793 loci) and mtDNA based phylogenetic hypothesis including all described and several undescribed species from six crater lakes (Apoyeque, Apoyo, Asososca Leon, Masaya, Tiscapa and Xiloá), the two great Lakes Managua and Nicaragua and the San Juan River. Our analyses demonstrate that the relationships between the Midas cichlid members are complex, and that phylogenetic information from different markers and methods do not always yield congruent results. Nevertheless, monophyly support for crater lake assemblages from Lakes Apoyeque, Apoyo, A. Leon is high as compared to those from L. Xiloá indicating occurrence of sympatric speciation. Further, we demonstrate that a 'three species' concept for the Midas cichlid complex is inapplicable and consequently that an individualized and voucher based approach in speciation research of the Midas cichlid complex is necessary at least as long as there is no comprehensive revision of the species complex available. Copyright 2010 Elsevier Inc. All rights reserved.

  18. Are sympatrically speciating Midas cichlid fish special? Patterns of morphological and genetic variation in the closely related species Archocentrus centrarchus.

    Science.gov (United States)

    Fruciano, Carmelo; Franchini, Paolo; Raffini, Francesca; Fan, Shaohua; Meyer, Axel

    2016-06-01

    Established empirical cases of sympatric speciation are scarce, although there is an increasing consensus that sympatric speciation might be more common than previously thought. Midas cichlid fish are one of the few substantiated cases of sympatric speciation, and they formed repeated radiations in crater lakes. In contrast, in the same environment, such radiation patterns have not been observed in other species of cichlids and other families of fish. We analyze morphological and genetic variation in a cichlid species (Archocentrus centrarchus) that co-inhabits several crater lakes with the Midas species complex. In particular, we analyze variation in body and pharyngeal jaw shape (two ecologically important traits in sympatrically divergent Midas cichlids) and relate that to genetic variation in mitochondrial control region and microsatellites. Using these four datasets, we analyze variation between and within two Nicaraguan lakes: a crater lake where multiple Midas cichlids have been described and a lake where the source population lives. We do not observe any within-lake clustering consistent across morphological traits and genetic markers, suggesting the absence of sympatric divergence in A. centrarchus. Genetic differentiation between lakes was low and morphological divergence absent. Such morphological similarity between lakes is found not only in average morphology, but also when analyzing covariation between traits and degree of morphospace occupation. A combined analysis of the mitochondrial control region in A. centrarchus and Midas cichlids suggests that a difference between lineages in the timing of crater lake colonization cannot be invoked as an explanation for the difference in their levels of diversification. In light of our results, A. centrarchus represents the ideal candidate to study the genomic differences between these two lineages that might explain why some lineages are more likely to speciate and diverge in sympatry than others.

  19. Ei Compendex: A new database makes life easier for engineers

    CERN Multimedia

    2001-01-01

    The Library is expanding its range of databases. The latest arrival, called Ei Compendex, is the world's most comprehensive engineering database, which indexes engineering literature published throughout the world. It also offers bibliographic entries for articles published in scientific journals and for conference proceedings and covers an extensive range of subjects from mechanical engineering to the environment, materials science, solid state physics and superconductivity. Moreover, it is the most relevant quality control and engineering management database. Ei Compendex contains over 4.6 million references from over 2600 journals, conference proceedings and technical reports dating from 1966 to the present. Every year, 220,000 new abstracts are added to the database which is also updated on a weekly basis. In the case of articles published in recent years, it provides an electronic link to the full texts of all major publishers. The database also contains the full texts of Elsevier periodicals (over 250...

  20. Keegi ei tea mu nime : [luuletused] / Veiko Märka

    Index Scriptorium Estoniae

    Märka, Veiko, 1964-

    2002-01-01

    Tõlgitud Veiko Märka luulekogust "Tühja aju korinad". Sisu: Keegi ei tea mu nime = Kukaan ei tiedä mun nimee ; "Kui ma kuulen sõnu..." = "Kun kuulen ilmauksen..." ; "Esimese..." = "Ensimmäisenä..." ; "Igal hommikul..." = "Joka aamu..." / tlk. Hannu Oittinen. Väike perenaine = Pikku perheenäiti / tlk. Hannu Oittinen ja Tuglas-seuran kääntäjäpiiri. Progressi triumf : (Poeem) = Kehityksen voitto : (Runoelma) / tlk. Hannu Oittinen. Minimalistlikud muinasjutud = Minimalistisia satuja / tlk. Heli Laaksonen ja Hannu Oittinen. Kõige turvalisem seks = Turvallisinta seksiä ; Abistame Aafrikat! = Autetaan Afrikkaa! ; "Taome..." = "Taotaan..." ; "Edasi..." = "Eteenpäin..." ; "Isegi juhus..." = "Edes sattuma..." ; "Miinus ja miinus..." = "Miinus ja miinus..." / tlk. Hannu Oittinen. Leijonien pakottaja ; Kotka ja Vaasa: Ystävyyskaupunkit

  1. CORONAL MASS EJECTION INDUCED OUTFLOWS OBSERVED WITH HINODE/EIS

    International Nuclear Information System (INIS)

    Jin, M.; Ding, M. D.; Chen, P. F.; Fang, C.; Imada, S.

    2009-01-01

    We investigate the outflows associated with two halo coronal mass ejections (CMEs) that occurred on 2006 December 13 and 14 in NOAA 10930, using the Hinode/EIS observations. Each CME was accompanied by an EIT wave and coronal dimmings. Dopplergrams in the dimming regions are obtained from the spectra of seven EIS lines. The results show that strong outflows are visible in the dimming regions during the CME eruption at different heights from the lower transition region to the corona. It is found that the velocity is positively correlated with the photospheric magnetic field, as well as the magnitude of the dimming. We estimate the mass loss based on height-dependent EUV dimmings and find it to be smaller than the CME mass derived from white-light observations. The mass difference is attributed partly to the uncertain atmospheric model, and partly to the transition region outflows, which refill the coronal dimmings.

  2. Feasibility of an EIS Follow-up Program

    International Nuclear Information System (INIS)

    Nelson, I.C.; Jaquish, R.E.; Watson, D.G.

    1982-12-01

    The proposed level of an EIS Follow-up Program is believed to be feasible and that it can and should be implemented. Guidance to authors should result in fewer, but more important, commitments for mitigating adverse environmental impacts. Selecting the significant commitments from Records of Decisions published since July 1, 1979 for tracking to satisfaction should result in conformance with regulations, orders, and the intent of the NEPA

  3. Iraagi raport ei veennud sõjavastaseid / Neeme Raud

    Index Scriptorium Estoniae

    Raud, Neeme, 1969-

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke, 12. sept. 2007, lk. 7. USA vägede ülemjuhataja kindral David Petraeus ja USA Iraagi suursaadik Ryuan Crocker kirjeldasid Kongressile Iraagi olukorda, mis ei suutnud sõja suhtes selgelt negatiivsetel positsioonidel rahvaesindajaid veenda, et operatsioonide jätkamine on vajalik. Vt. samas: Ingvar Bärenklau. Riigikogu peab otsustama Eesti missiooni saatuse

  4. Reformierakond ei kauple põhimõtetega / Meelis Atonen

    Index Scriptorium Estoniae

    Atonen, Meelis, 1966-

    2001-01-01

    Ilmunud ka: Hiiu Leht, 11. dets. 2001, lk. 2; Nädaline, 11. dets. 2001, lk. 4; Valgamaalane, 11. dets. 2001, lk. 2; Järva Teataja, 11. dets. 2001, lk. 2; Kesknädal, 19. dets. 2001, lk. 5. Tallinna võimuliidu lagunemise peapõhjus oli Tallinna 2002. aasta eelarvesse kavandatud 900 mln kuni 1,5 mld krooni suurune laen, millega Reformierakond ei ole kunagi nõustnud. Autor: Reformierakond. Parlamendisaadik

  5. Eesti ei pea ümberasujatele midagi tagastama / Helle Kalda

    Index Scriptorium Estoniae

    Kalda, Helle, 1950-

    2006-01-01

    Omandireformi aluste seaduse 7 paragrahvi lõikest 3 ja varade tagastamisest nn. järelümberasunutele. Sama ka Meie Maa 12. jaan. 2006, lk. 2 ; Vooremaa 17. jaan. 2006, lk. 2 ; Virumaa Teataja 2. veeb. 2006, lk. 11 ; Pärnu Postimees 9. veeb. 2006, lk. 15 ; Pärnu Postimees 9. veeb. 2006, lk. 15, pealkiri kujul : Ümberasujatele ei pea midagi tagastama

  6. EIS immunosensor based on magnetic nanoparticles for ochratoxim A determination

    International Nuclear Information System (INIS)

    Biraruti, Irina; Tudorache, Madalina; Rotariu, Lucian; Bala, Camelia; Jaffrezic-Renault, Nicole

    2009-01-01

    Full text: Ochratoxin A (OTA) is a mycotoxin produced by Aspergillus and Penicillium fungi. It occurs in a variety of foodstuff, including cereals, coffee, wine, grape juice and fruits juice. Maximum permitted levels have been established by the EU and several countries. Currently, there are several methods available for OTA monitoring in real samples, e.g. TLC, HPLC, ELISA immunosensors. Liquid chromatography with fluorescence detection (HPLC-FLD), coupled with immunoaffinity column or solid phase extraction as pretreatment method, has been validated and adopted as official standard for OTA determination. Also, an immunosensor based on electrochemical detection has been reported for rapid analysis of OTA in food and beverages. Our work proposes the development of a new sensitive immunosensor combining the use of magnetic nanoparticles and EIS (electrochemical impedance spectroscopy) detection principle. Anti-OTA antibody immobilised on magnetic nanoparticles were deposited on the EIS electrode surface by applying a magnetic field. Then, OTA sample solutions were added in the detection cell. Quantitative determination of OTA content was performed based on EIS detection. Experimental parameters of the immunosensor were set-up at the optimum values. Based on those values, the immunosensor allows to detect OTA in the range 1-10 ng/mL. The future perspective is to validate this immunochemical method using HPLC-FLD. (authors)

  7. Epilepsy, E/I balance and GABAA receptor plasticity

    Directory of Open Access Journals (Sweden)

    Jean-Marc Fritschy

    2008-03-01

    Full Text Available GABAA receptors mediate most of the fast inhibitory transmission in the CNS. They form heteromeric complexes assembled from a large family of subunit genes. The existence of multiple GABAA receptor subtypes differing in subunit composition, localization and functional properties underlies their role for fi ne-tuning of neuronal circuits and genesis of network oscillations. The differential regulation of GABAA receptor subtypes represents a major facet of homeostatic synaptic plasticity and contributes to the excitation/inhibition (E/I balance under physiological conditions and upon pathological challenges. The purpose of this review is to discuss recent fi ndings highlighting the signifi cance of GABAA receptor heterogeneity for the concept of E/I balance and its relevance for epilepsy. Specifi cally, we address the following issues: (1 role for tonic inhibition, mediated by extrasynaptic GABAA receptors, for controlling neuronal excitability; (2 signifi cance of chloride ion transport for maintenance of the E/I balance in adult brain; and (3 molecular mechanisms underlying GABAA receptor regulation (traffi cking, posttranslational modifi cation, gene transcription that are important for homoeostatic plasticity. Finally, the relevance of these fi ndings is discussed in light of the involvement of GABAA receptors in epileptic disorders, based on recent experimental studies of temporal lobe epilepsy (TLE and absence seizures and on the identifi cation of mutations in GABAA receptor subunit genes underlying familial forms of epilepsy.

  8. Acculturation of Iranians in the United States, the United Kingdom, and the Netherlands A Test of the Multidimensional Individual Difference Acculturation (MIDA) Model

    NARCIS (Netherlands)

    Safdar, S.; Struthers, W.; Van Oudenhoven, J.P.

    The present study tested the generalizability of a multidimensional individual difference acculturation (MIDA) model in three cultural contexts. The model includes three predictor variables (Psychosocial Resources, Connectedness, and Hassles), predicting three outcome adaptation variables (In-Group

  9. The Scope Calculation for the Distribution of the Plate-out in the 'OGL-1' experiment using MIDAS and Its model review

    International Nuclear Information System (INIS)

    Park, Jong-Hwa; Kim, Dong-Ha; Lee, Won-Jae

    2007-01-01

    The scope calculation on the plate-out in the HTGR related OGL-1 experiment using the MIDAS code was performed in the frame of the preliminary study to develop the MIDAS/GCR for simulating the plate-out, dust and tritium in a HTGR. From this scope calculation, the user specified type of the fission product vapor species in the circuit and the distribution of the circuit surface temperature were identified as the important factors that can have a strong effect on the distribution of fission product plate out over the HTGR loop. Also the analytical solution for calculating the plate-out by considering a radioactive decay was derived for MIDAS. These identified factors and the new analytical solution will be taken into account in developing the MIDAS/GCR

  10. A sensitive mass spectrometric method for hypothesis-driven detection of peptide post-translational modifications: multiple reaction monitoring-initiated detection and sequencing (MIDAS).

    Science.gov (United States)

    Unwin, Richard D; Griffiths, John R; Whetton, Anthony D

    2009-01-01

    The application of a targeted mass spectrometric workflow to the sensitive identification of post-translational modifications is described. This protocol employs multiple reaction monitoring (MRM) to search for all putative peptides specifically modified in a target protein. Positive MRMs trigger an MS/MS experiment to confirm the nature and site of the modification. This approach, termed MIDAS (MRM-initiated detection and sequencing), is more sensitive than approaches using neutral loss scanning or precursor ion scanning methodologies, due to a more efficient use of duty cycle along with a decreased background signal associated with MRM. We describe the use of MIDAS for the identification of phosphorylation, with a typical experiment taking just a couple of hours from obtaining a peptide sample. With minor modifications, the MIDAS method can be applied to other protein modifications or unmodified peptides can be used as a MIDAS target.

  11. Evaluation of the Structure Stability of a Plate Girder Bridge Using MIDAS Structure Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Eui Soo; Kim, Jong Hyuk [National Forensic Service, Wonju (Korea, Republic of)

    2014-04-15

    Recently, as a means of resolving the issue of legal liability in the event of an accident or a disaster, a wide variety of simulation techniques, such as structural and structure-fluid interaction analysis, have been used in the field of forensic engineering. The plate girder bridge discussed in this paper was being constructed between a pier and an abutment to expand an existing bridge, but an accident whereby the bridge overturned occurred at the end of the concrete laying process for a protective wall. This accident was caused by additional loads not being considered at the time of the design as well as the actual construction being different from the design. The additional loads ultimately generated a negative support force. In this study, we determined the cause of the accident by comparing the structural stability of the original design with that of the additional, non-conforming construction using MIDAS structural analysis.

  12. The meaning of the virtual Midas touch: an ERP study in economic decision making.

    Science.gov (United States)

    Spapé, Michiel M; Hoggan, Eve E; Jacucci, Giulio; Ravaja, Niklas

    2015-03-01

    The Midas touch refers to the altruistic effects of a brief touch. Though these effects have often been replicated, they remain poorly understood. We investigate the psychophysiology of the effect using remotely transmitted, precisely timed, tactile messages in an economic decision-making game called Ultimatum. Participants were more likely to accept offers after receiving a remotely transmitted touch. Furthermore, we found distinct effects of touch on event-related potentials evoked by (a) feedback regarding accepted and rejected offers, (b) decision cues related to proposals, and (c) the haptic and auditory cues themselves. In each case, a late positive effect of touch was observed and related to the P3. Given the role of the P3 in memory-related functions, the results indicate an indirect relationship between touch and generosity that relies on memory. This hypothesis was further tested and confirmed in the positive effects of touch on later proposals. © 2014 Society for Psychophysiological Research.

  13. Post-test analysis for the MIDAS DVI tests using MARS

    International Nuclear Information System (INIS)

    Bae, K. H.; Lee, Y. J.; Kwon, T. S.; Lee, W. J.; Kim, H. C.

    2002-01-01

    Various DVI tests have been performed at MIDAS test facility which is a scaled facility of APR1400 applying a modified linear scale ratio. The evaluation results for the various void height tests and direct bypass tests using a multi-dimensional best-estimate analysis code MARS, show that; (a) MARS code has an advanced modeling capability of well predicting major multi-dimensional thermal-hydraulic phenomena occurring in the downcomer, (b) MARS code under-predicts the steam condensation rates, which in turn causes to over-predict the ECC bypass rates. However, the trend of decrease in steam condensation rate and increase in ECC bypass rate in accordance with the increase in steam flow rate, and the calculation results of the ECC bypass rates under the EM analysis conditions generally agree with the test data

  14. Evaluation of the Structure Stability of a Plate Girder Bridge Using MIDAS Structure Analysis

    International Nuclear Information System (INIS)

    Kim, Eui Soo; Kim, Jong Hyuk

    2014-01-01

    Recently, as a means of resolving the issue of legal liability in the event of an accident or a disaster, a wide variety of simulation techniques, such as structural and structure-fluid interaction analysis, have been used in the field of forensic engineering. The plate girder bridge discussed in this paper was being constructed between a pier and an abutment to expand an existing bridge, but an accident whereby the bridge overturned occurred at the end of the concrete laying process for a protective wall. This accident was caused by additional loads not being considered at the time of the design as well as the actual construction being different from the design. The additional loads ultimately generated a negative support force. In this study, we determined the cause of the accident by comparing the structural stability of the original design with that of the additional, non-conforming construction using MIDAS structural analysis

  15. The MIDAS experiment: A prototype for the microwave emission of Ultra-High Energy Cosmic Rays

    International Nuclear Information System (INIS)

    Monasor, M.; Alekotte, I.; Alvarez-Muniz, J.; Berlin, A.; Bertou, X.; Bodgan, M.; Bohacova, M.; Bonifazi, C.; Carvalho, W.; Mello Neto, J.R.T. de; Genat, J.F.; Facal San Luis, P.; Mills, E.; Rouille d'Orfeuil, B.; Wayne, S.; Reyes, L.C.; Santos, E.M.; Privitera, P.; Williams, C.; Zas, E.

    2011-01-01

    Recent measurements suggest that extensive air showers initiated by ultra-high energy cosmic rays (UHECR) emit signals in the microwave band of the electromagnetic spectrum caused by the collisions of the free-electrons with the atmospheric neutral molecules in the plasma produced by the passage of the shower. Such emission is isotropic and could allow the detection of air showers with 100% duty cycle and a calorimetric-like energy measurement, a significant improvement over current detection techniques. We have built MIDAS (MIcrowave Detection of Air Showers), a prototype of microwave detector, which consists of a 4.5 m diameter antenna with a cluster of 53 feed-horns in the 4 GHz range. The details of the prototype and first results will be presented.

  16. A Restructuring of the HS Package for the MIDAS Computer Code

    International Nuclear Information System (INIS)

    Park, S. H.; Kim, K. R.; Kim, D. H.; Cho, S. W.

    2005-01-01

    As one of the processes for a localized severe accident analysis code, KAERI is developing a severe accident code MIDAS, based on MELCOR. The existing data saving method uses pointer variables for a fix-sized storage management, and it deteriorates the readability, maintainability and portability of the code. But new features in FORTRAN90 such as a dynamic allocation have been used for the restructuring. The restructuring of the data saving and transferring method of the existing code makes it easy to understand the code. Before an entire restructuring of the code, a restructuring template for a simple package was developed and tested. The target for the restructuring was the HS package which is responsible for calculation the heat conduction within an intact, solid structure and energy transfer across its boundary surfaces into control volumes. The verification was done through comparing the results before and after the restructuring

  17. A restructuring of the FL package for the MIDAS computer code

    International Nuclear Information System (INIS)

    Park, S. H.; Kim, K. R.; Kim, D. H.; Cho, S. W.

    2005-01-01

    The developmental need for a localized severe accident analysis code is on the rise, and KAERI is developing a severe accident code MIDAS, based on MELCOR. The existing data saving method uses pointer variables for a fix-sized storage management, and it deteriorates the readability, maintainability and portability of the code. But new features in FORTRAN90 such as a dynamic allocation have been used for the restructuring. The restructuring of the data saving and transferring method of the existing code makes it easy to understand the code. Before an entire restructuring of the code, a restructuring template for a simple package was developed and tested. The target for the restructuring was the FL package which is responsible for modeling the thermal-hydraulic behavior of a liquid water, water vapor, and gases in MELCOR with the CVH package. The verification was done through comparing the results before and after the restructuring

  18. Hot money and China's stock market volatility: Further evidence using the GARCH-MIDAS model

    Science.gov (United States)

    Wei, Yu; Yu, Qianwen; Liu, Jing; Cao, Yang

    2018-02-01

    This paper investigates the influence of hot money on the return and volatility of the Chinese stock market using a nonlinear Granger causality test and a new GARCH-class model based on mixed data sampling regression (GARCH-MIDAS). The empirical results suggest that no linear or nonlinear causality exists between the growth rate of hot money and the Chinese stock market return, implying that the Chinese stock market is not driven by hot money and vice versa. However, hot money has a significant positive impact on the long-term volatility of the Chinese stock market. Furthermore, the dependence between the long-term volatility caused by hot money and the total volatility of the Chinese stock market is time-variant, indicating that huge volatilities in the stock market are not always triggered by international speculation capital flow and that Chinese authorities should further focus on more systemic reforms in the trading rules and on effectively regulating the stock market.

  19. Long- and Short-Term Cryptocurrency Volatility Components: A GARCH-MIDAS Analysis

    Directory of Open Access Journals (Sweden)

    Christian Conrad

    2018-05-01

    Full Text Available We use the GARCH-MIDAS model to extract the long- and short-term volatility components of cryptocurrencies. As potential drivers of Bitcoin volatility, we consider measures of volatility and risk in the US stock market as well as a measure of global economic activity. We find that S&P 500 realized volatility has a negative and highly significant effect on long-term Bitcoin volatility. The finding is atypical for volatility co-movements across financial markets. Moreover, we find that the S&P 500 volatility risk premium has a significantly positive effect on long-term Bitcoin volatility. Finally, we find a strong positive association between the Baltic dry index and long-term Bitcoin volatility. This result shows that Bitcoin volatility is closely linked to global economic activity. Overall, our findings can be used to construct improved forecasts of long-term Bitcoin volatility.

  20. Identification and characterization of miRNAs transcriptome in the South African abalone, Haliotis midae.

    Science.gov (United States)

    Picone, Barbara; Rhode, Clint; Roodt-Wilding, Rouvay

    2017-02-01

    Aquatic animal diseases are one of the most important limitations to the growth of aquaculture. miRNAs represent an important class of small ncRNAs able to modulate host immune and stress responses. In Mollusca, a large phylum of invertebrates, miRNAs have been identified in several species. The current preliminary study identified known miRNAs from the South African abalone, Haliotis midae. The economic and ecological importance of abalone makes this species a suitable model for studying and understanding stress response in marine gastropods. Furthermore, the identification of miRNA, represents an alternative and powerful tool to combat infectious disease. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. A midas plugin to enable construction of reproducible web-based image processing pipelines.

    Science.gov (United States)

    Grauer, Michael; Reynolds, Patrick; Hoogstoel, Marion; Budin, Francois; Styner, Martin A; Oguz, Ipek

    2013-01-01

    Image processing is an important quantitative technique for neuroscience researchers, but difficult for those who lack experience in the field. In this paper we present a web-based platform that allows an expert to create a brain image processing pipeline, enabling execution of that pipeline even by those biomedical researchers with limited image processing knowledge. These tools are implemented as a plugin for Midas, an open-source toolkit for creating web based scientific data storage and processing platforms. Using this plugin, an image processing expert can construct a pipeline, create a web-based User Interface, manage jobs, and visualize intermediate results. Pipelines are executed on a grid computing platform using BatchMake and HTCondor. This represents a new capability for biomedical researchers and offers an innovative platform for scientific collaboration. Current tools work well, but can be inaccessible for those lacking image processing expertise. Using this plugin, researchers in collaboration with image processing experts can create workflows with reasonable default settings and streamlined user interfaces, and data can be processed easily from a lab environment without the need for a powerful desktop computer. This platform allows simplified troubleshooting, centralized maintenance, and easy data sharing with collaborators. These capabilities enable reproducible science by sharing datasets and processing pipelines between collaborators. In this paper, we present a description of this innovative Midas plugin, along with results obtained from building and executing several ITK based image processing workflows for diffusion weighted MRI (DW MRI) of rodent brain images, as well as recommendations for building automated image processing pipelines. Although the particular image processing pipelines developed were focused on rodent brain MRI, the presented plugin can be used to support any executable or script-based pipeline.

  2. Testing the carotenoid trade-off hypothesis in the polychromatic Midas cichlid, Amphilophus citrinellus.

    Science.gov (United States)

    Lin, Susan M; Nieves-Puigdoller, Katherine; Brown, Alexandria C; McGraw, Kevin J; Clotfelter, Ethan D

    2010-01-01

    Many animals use carotenoid pigments derived from their diet for coloration and immunity. The carotenoid trade-off hypothesis predicts that, under conditions of carotenoid scarcity, individuals may be forced to allocate limited carotenoids to either coloration or immunity. In polychromatic species, the pattern of allocation may differ among individuals. We tested the carotenoid trade-off hypothesis in the Midas cichlid, Amphilophus citrinellus, a species with two ontogenetic color morphs, barred and gold, the latter of which is the result of carotenoid expression. We performed a diet-supplementation experiment in which cichlids of both color morphs were assigned to one of two diet treatments that differed only in carotenoid content (beta-carotene, lutein, and zeaxanthin). We measured integument color using spectrometry, quantified carotenoid concentrations in tissue and plasma, and assessed innate immunity using lysozyme activity and alternative complement pathway assays. In both color morphs, dietary carotenoid supplementation elevated plasma carotenoid circulation but failed to affect skin coloration. Consistent with observable differences in integument coloration, we found that gold fish sequestered more carotenoids in skin tissue than barred fish, but barred fish had higher concentrations of carotenoids in plasma than gold fish. Neither measure of innate immunity differed between gold and barred fish, or as a function of dietary carotenoid supplementation. Lysozyme activity, but not complement activity, was strongly affected by body condition. Our data show that a diet low in carotenoids is sufficient to maintain both coloration and innate immunity in Midas cichlids. Our data also suggest that the developmental transition from the barred to gold morph is not accompanied by a decrease in innate immunity in this species.

  3. A Midas Plugin to Enable Construction of Reproducible Web-based Image Processing Pipelines

    Directory of Open Access Journals (Sweden)

    Michael eGrauer

    2013-12-01

    Full Text Available Image processing is an important quantitative technique for neuroscience researchers, but difficult for those who lack experience in the field. In this paper we present a web-based platform that allows an expert to create a brain image processing pipeline, enabling execution of that pipeline even by those biomedical researchers with limited image processing knowledge. These tools are implemented as a plugin for Midas, an open-source toolkit for creating web based scientific data storage and processing platforms. Using this plugin, an image processing expert can construct a pipeline, create a web-based UI, manage jobs, and visualize intermediate results. Pipelines are executed on a grid computing platform using BatchMake and HTCondor. This represents a new capability for biomedical researchers and offers an innovative platform for scientific collaboration. Current tools work well, but can be inaccessible for those lacking image processing expertise. Using this plugin, researchers in collaboration with image processing experts can create workflows with reasonable default settings and streamlined user interfaces, and data can be processed easily from a lab environment without the need for a powerful desktop computer. This platform allows simplified troubleshooting, centralized maintenance, and easy data sharing with collaborators. These capabilities enable reproducible science by sharing datasets and processing pipelines between collaborators. In this paper, we present a description of this innovative Midas plugin, along with results obtained from building and executing several ITK based image processing workflows for diffusion weighted MRI (DW MRI of rodent brain images, as well as recommendations for building automated image processing pipelines. Although the particular image processing pipelines developed were focused on rodent brain MRI, the presented plugin can be used to support any executable or script-based pipeline.

  4. Gonad development in Midas cichlids and the evolution of sex change in fishes.

    Science.gov (United States)

    Oldfield, Ronald G

    2011-01-01

    Some fishes mature and function as one sex and later transform to the other sex in response to social interactions. Previous evidence suggested that a change in developmental timing may be involved in the evolution of adult sex change in fishes. The most recent support for this idea came from reports that sex in the Midas cichlid, Amphilophus citrinellus, was determined by social conditions experienced at the juvenile stage. Differentiation as a male was reported to be dependent on large body size relative to group-mates, and thought to be mediated through aggressive interactions. Here I demonstrate that socially controlled sex determination does not occur as was originally reported. Previously, I found that sex was not associated with body size in juveniles either in nature or in captivity. Similarly, I found no association between aggressive behavior and sex in juveniles. I later demonstrated that socially controlled sex determination does not typically occur in the Midas cichlid and closely related species and supported an alternative mechanism to explain large body size in adult males. Finally, in the current study I analyze gonad histology of fish from the same population used by the original authors and lay to rest the idea of socially controlled sex determination in this species. Recent observations of socially controlled sex determination in juveniles of species that typically change sex at the adult stage are examples of phenotypic plasticity, not genetic variation. Therefore, juvenile socially controlled sex determination does not support a theory that a change in developmental timing is involved in the evolution of adult sex change in fishes. © 2011 Wiley Periodicals, Inc.

  5. The cross-tissue metabolic response of abalone (Haliotis midae) to functional hypoxia.

    Science.gov (United States)

    Venter, Leonie; Loots, Du Toit; Mienie, Lodewyk J; Jansen van Rensburg, Peet J; Mason, Shayne; Vosloo, Andre; Lindeque, Jeremie Z

    2018-03-23

    Functional hypoxia is a stress condition caused by the abalone itself as a result of increased muscle activity, which generally necessitates the employment of anaerobic metabolism if the activity is sustained for prolonged periods. With that being said, abalone are highly reliant on anaerobic metabolism to provide partial compensation for energy production during oxygen-deprived episodes. However, current knowledge on the holistic metabolic response for energy metabolism during functional hypoxia, and the contribution of different metabolic pathways and various abalone tissues towards the overall accumulation of anaerobic end-products in abalone are scarce. Metabolomics analysis of adductor muscle, foot muscle, left gill, right gill, haemolymph and epipodial tissue samples indicated that South African abalone ( Haliotis midae) subjected to functional hypoxia utilises predominantly anaerobic metabolism, and depends on all of the main metabolite classes (proteins, carbohydrates and lipids) for energy supply. Functional hypoxia caused increased levels of anaerobic end-products: lactate, alanopine, tauropine, succinate and alanine. Also, elevation in arginine levels was detected, confirming that abalone use phosphoarginine to generate energy during functional hypoxia. Different tissues showed varied metabolic responses to hypoxia, with functional hypoxia showing excessive changes in the adductor muscle and gills. From this metabolomics investigation, it becomes evident that abalone are metabolically able to produce sufficient amounts of energy when functional hypoxia is experienced. Also, tissue interplay enables the adjustment of H. midae energy requirements as their metabolism shifts from aerobic to anaerobic respiration during functional hypoxia.This article has an associated First Person interview with the first author of the paper. © 2018. Published by The Company of Biologists Ltd.

  6. The cross-tissue metabolic response of abalone (Haliotis midae to functional hypoxia

    Directory of Open Access Journals (Sweden)

    Leonie Venter

    2018-03-01

    Full Text Available Functional hypoxia is a stress condition caused by the abalone itself as a result of increased muscle activity, which generally necessitates the employment of anaerobic metabolism if the activity is sustained for prolonged periods. With that being said, abalone are highly reliant on anaerobic metabolism to provide partial compensation for energy production during oxygen-deprived episodes. However, current knowledge on the holistic metabolic response for energy metabolism during functional hypoxia, and the contribution of different metabolic pathways and various abalone tissues towards the overall accumulation of anaerobic end-products in abalone are scarce. Metabolomics analysis of adductor muscle, foot muscle, left gill, right gill, haemolymph and epipodial tissue samples indicated that South African abalone (Haliotis midae subjected to functional hypoxia utilises predominantly anaerobic metabolism, and depends on all of the main metabolite classes (proteins, carbohydrates and lipids for energy supply. Functional hypoxia caused increased levels of anaerobic end-products: lactate, alanopine, tauropine, succinate and alanine. Also, elevation in arginine levels was detected, confirming that abalone use phosphoarginine to generate energy during functional hypoxia. Different tissues showed varied metabolic responses to hypoxia, with functional hypoxia showing excessive changes in the adductor muscle and gills. From this metabolomics investigation, it becomes evident that abalone are metabolically able to produce sufficient amounts of energy when functional hypoxia is experienced. Also, tissue interplay enables the adjustment of H. midae energy requirements as their metabolism shifts from aerobic to anaerobic respiration during functional hypoxia. This article has an associated First Person interview with the first author of the paper.

  7. Miks mind ei märgata? Kohe selgitame! / Priit Pullerits

    Index Scriptorium Estoniae

    Pullerits, Priit, 1965-

    2011-01-01

    Martin Salo ja Mihkel Jäätmaa on loonud revolutsioonilise pilgujälgimise ning emotsioonide mõõtmise ja analüüsi süsteemi, mida kasutavad maailma suurfirmad eBay, Sony, IKEA, Barclays ja paljud teised. Ettevõttest Realeyes

  8. Leo Kunnas : triibuline särk kuuli ei peata / Leo Kunnas ; interv. Jaanus Piirsalu

    Index Scriptorium Estoniae

    Kunnas, Leo, 1967-

    2006-01-01

    2005. aastal koalitsioonijõudude koosseisus Iraagis teeninud Leo Kunnas selgitab intervjuus, mida on Eesti kaitsevägi Iraagi missioonist õppinud, millist mõju on Eesti sõdurite osalemine välismissioonides avaldanud ühiskonnale, lisaks võrdleb Iraagi ja Afganistani missioone ning põhjendab, miks on palgaarmee loomise idee Eestis sõjaliselt mitterelevantne

  9. Draft Executive Summary Hawaii Geothermal Project - EIS Scoping Meetings

    Energy Technology Data Exchange (ETDEWEB)

    None

    1992-03-01

    After introductions by the facilitator and the program director from DOE, process questions were entertained. It was also sometimes necessary to make clarifications as to process throughout the meetings. Topics covered federal involvement in the HGP-EIS; NEPA compliance; public awareness, review, and access to information; Native Hawaiian concerns; the record of decision, responsibility with respect to international issues; the impacts of prior and on-going geothermal development activities; project definition; alternatives to the proposed action; necessary studies; Section 7 consultations; socioeconomic impacts; and risk analysis. Presentations followed, in ten meetings, 163 people presented issues and concerns, 1 additional person raised process questions only.

  10. [Cross-cultural adaptation of the Myocardial Infarction Dimensional Assessment Scale (MIDAS) to the Brazilian Portuguese language].

    Science.gov (United States)

    Fiorin, Bruno Henrique; Oliveira, Elizabete Regina Araújo de; Moreira, Rita Simone Lopes; Luna Filho, Bráulio

    2018-03-01

    From the evaluation of the factors that affect quality of life (QOL) it is possible to plan interventions that lead to the improved well-being of patients. The scope of this study was to conduct the cross-cultural adaptation of the Myocardial Infarction Dimensional Assessment Scale (MIDAS) questionnaire to the Portuguese language, seeking the necessary semantic, idiomatic, conceptual and cultural equivalence. The theoretical framework of Guillemin, Bombardier and Beaton was used, fulfilling the following steps: translation, back translation, evaluation of the authors, peer review and pre-testing. After all the tests, the semantic, idiomatic, conceptual and cultural equivalence was achieved. The scale proved to be easy to use and was clinically important. MIDAS was validated in terms of its semantic, idiomatic, conceptual and cultural equivalences. Subsequently, the measurement equivalence will be evaluated to verify the psychometric properties.

  11. MiDAS Field Guide – a Comprehensive Online Source of Information About the Microbes of Activated Sludge

    DEFF Research Database (Denmark)

    Nierychlo, Marta; McIlroy, Simon Jon; Saunders, Aaron Marc

    activated sludge wastewater treatment systems, linking their identity with available information on their function and distribution. The guide includes the approx. 100 abundant genera that are present in most treatment plants (based on a survey of 25 full-scale Danish wastewater treatment plants...... are provided. The MiDAS Field Guide is a continuously developing resource where all working in the field are invited to contribute....... that would be otherwise excluded from analyses. The MiDAS database importantly provides a common taxonomy for the field that gives a solid foundation for the study of microbial ecology of the activated sludge process and related wastewater treatment processes, such as biofilms and granular sludge. Each genus...

  12. Biochemical and Structural Analysis of an Eis Family Aminoglycoside Acetyltransferase from Bacillus anthracis

    Energy Technology Data Exchange (ETDEWEB)

    Green, Keith D.; Biswas, Tapan; Chang, Changsoo; Wu, Ruiying; Chen, Wenjing; Janes, Brian K.; Chalupska, Dominika; Gornicki, Piotr; Hanna, Philip C.; Tsodikov, Oleg V.; Joachimiak, Andrzej; Garneau-Tsodikova, Sylvie

    2015-05-26

    Proteins from the enhanced intracellular survival (Eis) family are versatile acetyltransferases that acetylate amines at multiple positions of several aminoglycosides (AGs). Their upregulation confers drug resistance. Homologues of Eis are present in diverse bacteria, including many pathogens. Eis from Mycobacterium tuberculosis (Eis_Mtb) has been well characterized. In this study, we explored the AG specificity and catalytic efficiency of the Eis family protein from Bacillus anthracis (Eis_Ban). Kinetic analysis of specificity and catalytic efficiency of acetylation of six AGs indicates that Eis_Ban displays significant differences from Eis_Mtb in both substrate binding and catalytic efficiency. The number of acetylated amines was also different for several AGs, indicating a distinct regiospecificity of Eis_Ban. Furthermore, most recently identified inhibitors of Eis_Mtb did not inhibit Eis_Ban, underscoring the differences between these two enzymes. To explain these differences, we determined an Eis_Ban crystal structure. The comparison of the crystal structures of Eis_Ban and Eis_Mtb demonstrates that critical residues lining their respective substrate binding pockets differ substantially, explaining their distinct specificities. Our results suggest that acetyltransferases of the Eis family evolved divergently to garner distinct specificities while conserving catalytic efficiency, possibly to counter distinct chemical challenges. The unique specificity features of these enzymes can be utilized as tools for developing AGs with novel modifications and help guide specific AG treatments to avoid Eis-mediated resistance.

  13. Phylogeography, colonization and population history of the Midas cichlid species complex (Amphilophus spp. in the Nicaraguan crater lakes

    Directory of Open Access Journals (Sweden)

    Meyer Axel

    2010-10-01

    Full Text Available Abstract Background Elucidation of the mechanisms driving speciation requires detailed knowledge about the phylogenetic relationships and phylogeography of the incipient species within their entire ranges as well as their colonization history. The Midas cichlid species complex Amphilophus spp. has been proven to be a powerful model system for the study of ecological specialization, sexual selection and the mechanisms of sympatric speciation. Here we present a comprehensive and integrative phylogeographic analysis of the complete Midas Cichlid species complex in Nicaragua (> 2000 individuals covering the entire distributional range, using two types of molecular markers (the mitochondrial DNA control region and 15 microsatellites. We investigated the majority of known lake populations of this species complex and reconstructed their colonization history in order to distinguish between alternative speciation scenarios. Results We found that the large lakes contain older and more diverse Midas Cichlid populations, while all crater lakes hold younger and genetically less variable species assemblages. The large lakes appear to have repeatedly acted as source populations for all crater lakes, and our data indicate that faunal exchange among crater lakes is extremely unlikely. Despite their very recent (often only a few thousand years old and common origin from the two large Nicaraguan lakes, all crater lake Midas Cichlid radiations underwent independent, but parallel, evolution, and comprise distinct genetic units. Indeed several of these crater lakes contain multiple genetically distinct incipient species that most likely arose through sympatric speciation. Several crater lake radiations can be traced back to a single ancestral line, but some appear to have more than one founding lineage. The timing of the colonization(s of each crater lake differs, although most of them occurred more (probably much more recently than 20,000 years ago. Conclusion The

  14. MiDas: automatic extraction of a common domain of discourse in sleep medicine for multi-center data integration.

    Science.gov (United States)

    Sahoo, Satya S; Ogbuji, Chimezie; Luo, Lingyun; Dong, Xiao; Cui, Licong; Redline, Susan S; Zhang, Guo-Qiang

    2011-01-01

    Clinical studies often use data dictionaries with controlled sets of terms to facilitate data collection, limited interoperability and sharing at a local site. Multi-center retrospective clinical studies require that these data dictionaries, originating from individual participating centers, be harmonized in preparation for the integration of the corresponding clinical research data. Domain ontologies are often used to facilitate multi-center data integration by modeling terms from data dictionaries in a logic-based language, but interoperability among domain ontologies (using automated techniques) is an unresolved issue. Although many upper-level reference ontologies have been proposed to address this challenge, our experience in integrating multi-center sleep medicine data highlights the need for an upper level ontology that models a common set of terms at multiple-levels of abstraction, which is not covered by the existing upper-level ontologies. We introduce a methodology underpinned by a Minimal Domain of Discourse (MiDas) algorithm to automatically extract a minimal common domain of discourse (upper-domain ontology) from an existing domain ontology. Using the Multi-Modality, Multi-Resource Environment for Physiological and Clinical Research (Physio-MIMI) multi-center project in sleep medicine as a use case, we demonstrate the use of MiDas in extracting a minimal domain of discourse for sleep medicine, from Physio-MIMI's Sleep Domain Ontology (SDO). We then extend the resulting domain of discourse with terms from the data dictionary of the Sleep Heart and Health Study (SHHS) to validate MiDas. To illustrate the wider applicability of MiDas, we automatically extract the respective domains of discourse from 6 sample domain ontologies from the National Center for Biomedical Ontologies (NCBO) and the OBO Foundry.

  15. Phylogeography, colonization and population history of the Midas cichlid species complex (Amphilophus spp.) in the Nicaraguan crater lakes.

    Science.gov (United States)

    Barluenga, Marta; Meyer, Axel

    2010-10-26

    Elucidation of the mechanisms driving speciation requires detailed knowledge about the phylogenetic relationships and phylogeography of the incipient species within their entire ranges as well as their colonization history. The Midas cichlid species complex Amphilophus spp. has been proven to be a powerful model system for the study of ecological specialization, sexual selection and the mechanisms of sympatric speciation. Here we present a comprehensive and integrative phylogeographic analysis of the complete Midas Cichlid species complex in Nicaragua (> 2000 individuals) covering the entire distributional range, using two types of molecular markers (the mitochondrial DNA control region and 15 microsatellites). We investigated the majority of known lake populations of this species complex and reconstructed their colonization history in order to distinguish between alternative speciation scenarios. We found that the large lakes contain older and more diverse Midas Cichlid populations, while all crater lakes hold younger and genetically less variable species assemblages. The large lakes appear to have repeatedly acted as source populations for all crater lakes, and our data indicate that faunal exchange among crater lakes is extremely unlikely. Despite their very recent (often only a few thousand years old) and common origin from the two large Nicaraguan lakes, all crater lake Midas Cichlid radiations underwent independent, but parallel, evolution, and comprise distinct genetic units. Indeed several of these crater lakes contain multiple genetically distinct incipient species that most likely arose through sympatric speciation. Several crater lake radiations can be traced back to a single ancestral line, but some appear to have more than one founding lineage. The timing of the colonization(s) of each crater lake differs, although most of them occurred more (probably much more) recently than 20,000 years ago. The genetic differentiation of the crater lake populations

  16. Imaging of irradiated liver with Tc-99m-sulfur colloid and Tc-99m-IDA

    International Nuclear Information System (INIS)

    Gelfand, M.J.; Saha, S.; Aron, B.S.

    1981-01-01

    In three cases, irradiated regions of liver failed to concentrate Tc-99m-sulfur colloid. In two of these three, imaging with Tc-99m-acetanilide iminodiacetic acid (IDA) agents within five days showed near normal hepatic uptake of this hepatobiliary imaging agent. The hepatic parenchymal cells may be imaged with Tc-99m-IDA in some irradiated regions of liver, despite loss of reticuloendothelial cell function

  17. Differential chromosomal organization between Saguinus midas and Saguinus bicolor with accumulation of differences the repetitive sequence DNA.

    Science.gov (United States)

    Serfaty, Dayane Martins Barbosa; Carvalho, Natália Dayane Moura; Gross, Maria Claudia; Gordo, Marcelo; Schneider, Carlos Henrique

    2017-10-01

    Saguinus is the largest and most complex genus of the subfamily Callitrichinae, with 23 species distributed from the south of Central America to the north of South America with Saguinus midas having the largest geographical distribution while Saguinus bicolor has a very restricted one, affected by the population expansion in the state of Amazonas. Considering the phylogenetic proximity of the two species along with evidence on the existence of hybrids between them, as well as cytogenetic studies on Saguinus describing a conserved karyotypic macrostructure, we carried out a physical mapping of DNA repeated sequences in the mitotic chromosome of both species, since these sequences are less susceptible to evolutionary pressure and possibly perform an important function in speciation. Both species presented 2n = 46 chromosomes; in S. midas, chromosome Y is the smallest. Multiple ribosomal sites occur in both species, but chromosome pairs three and four may be regarded as markers that differ the species when subjected to G banding and distribution of retroelement LINE 1, suggesting that it may be cytogenetic marker in which it can contribute to identification of first generation hybrids in contact zone. Saguinus bicolor also presented differences in the LINE 1 distribution pattern for sexual chromosome X in individuals from different urban fragments, probably due to geographical isolation. In this context, cytogenetic analyses reveal a differential genomic organization pattern between species S. midas and S. bicolor, in addition to indicating that individuals from different urban fragments have been accumulating differences because of the isolation between them.

  18. Computerized back postural assessment in physiotherapy practice: Intra-rater and inter-rater reliability of the MIDAS system.

    Science.gov (United States)

    McAlpine, R T; Bettany-Saltikov, J A; Warren, J G

    2009-01-01

    Assessment of spinal posture during physiotherapy practice is routine, yet few objective measures exist to this end. The Middlesbrough Integrated Digital Assessment System (MIDAS) is a low cost portable system able to record 3D information on posture. The purpose of this study was to assess both the intra-rater and inter-rater reliability of the MIDAS system. Twenty-five healthy subjects were recruited. A repeated measures design was used to record fifteen pre-palpated landmarks on the back of each subject. To limit the sources of variability, the principal researcher palpated the landmarks for each subject. Each of three raters took two measurements on each subject in a standardized upright posture. X (medio-lateral), Y (antero-posterior) and Z (height) landmark positions were recorded via a computer interface. Both intra-rater agreement (mean ICCs - rater 1 r=0.970, rater 2 r=0.965 and rater 3 r=0.965, pMIDAS demonstrated both high inter-rater and intra-rater reliability and provides an objective method for the assessment of posture in physiotherapy practice.

  19. Re-Design and Beat Testing of the Man-Machine Integration Design and Analysis System: MIDAS

    Science.gov (United States)

    Shively, R. Jay; Rutkowski, Michael (Technical Monitor)

    1999-01-01

    The Man-machine Design and Analysis System (MIDAS) is a human factors design and analysis system that combines human cognitive models with 3D CAD models and rapid prototyping and simulation techniques. MIDAS allows designers to ask 'what if' types of questions early in concept exploration and development prior to actual hardware development. The system outputs predictions of operator workload, situational awareness and system performance as well as graphical visualization of the cockpit designs interacting with models of the human in a mission scenario. Recently, MIDAS was re-designed to enhance functionality and usability. The goals driving the redesign include more efficient processing, GUI interface, advances in the memory structures, implementation of external vision models and audition. These changes were detailed in an earlier paper. Two Beta test sites with diverse applications have been chosen. One Beta test site is investigating the development of a new airframe and its interaction with the air traffic management system. The second Beta test effort will investigate 3D auditory cueing in conjunction with traditional visual cueing strategies including panel-mounted and heads-up displays. The progress and lessons learned on each of these projects will be discussed.

  20. Rapid adaptation to a novel light environment: The importance of ontogeny and phenotypic plasticity in shaping the visual system of Nicaraguan Midas cichlid fish (Amphilophus citrinellus spp.).

    Science.gov (United States)

    Härer, Andreas; Torres-Dowdall, Julián; Meyer, Axel

    2017-10-01

    Colonization of novel habitats is typically challenging to organisms. In the initial stage after colonization, approximation to fitness optima in the new environment can occur by selection acting on standing genetic variation, modification of developmental patterns or phenotypic plasticity. Midas cichlids have recently colonized crater Lake Apoyo from great Lake Nicaragua. The photic environment of crater Lake Apoyo is shifted towards shorter wavelengths compared to great Lake Nicaragua and Midas cichlids from both lakes differ in visual sensitivity. We investigated the contribution of ontogeny and phenotypic plasticity in shaping the visual system of Midas cichlids after colonizing this novel photic environment. To this end, we measured cone opsin expression both during development and after experimental exposure to different light treatments. Midas cichlids from both lakes undergo ontogenetic changes in cone opsin expression, but visual sensitivity is consistently shifted towards shorter wavelengths in crater lake fish, which leads to a paedomorphic retention of their visual phenotype. This shift might be mediated by lower levels of thyroid hormone in crater lake Midas cichlids (measured indirectly as dio2 and dio3 gene expression). Exposing fish to different light treatments revealed that cone opsin expression is phenotypically plastic in both species during early development, with short and long wavelength light slowing or accelerating ontogenetic changes, respectively. Notably, this plastic response was maintained into adulthood only in the derived crater lake Midas cichlids. We conclude that the rapid evolution of Midas cichlids' visual system after colonizing crater Lake Apoyo was mediated by a shift in visual sensitivity during ontogeny and was further aided by phenotypic plasticity during development. © 2017 John Wiley & Sons Ltd.

  1. Tol2 transposon-mediated transgenesis in the Midas cichlid (Amphilophus citrinellus) - towards understanding gene function and regulatory evolution in an ecological model system for rapid phenotypic diversification.

    Science.gov (United States)

    Kratochwil, Claudius F; Sefton, Maggie M; Liang, Yipeng; Meyer, Axel

    2017-11-23

    The Midas cichlid species complex (Amphilophus spp.) is widely known among evolutionary biologists as a model system for sympatric speciation and adaptive phenotypic divergence within extremely short periods of time (a few hundred generations). The repeated parallel evolution of adaptive phenotypes in this radiation, combined with their near genetic identity, makes them an excellent model for studying phenotypic diversification. While many ecological and evolutionary studies have been performed on Midas cichlids, the molecular basis of specific phenotypes, particularly adaptations, and their underlying coding and cis-regulatory changes have not yet been studied thoroughly. For the first time in any New World cichlid, we use Tol2 transposon-mediated transgenesis in the Midas cichlid (Amphilophus citrinellus). By adapting existing microinjection protocols, we established an effective protocol for transgenesis in Midas cichlids. Embryos were injected with a Tol2 plasmid construct that drives enhanced green fluorescent protein (eGFP) expression under the control of the ubiquitin promoter. The transgene was successfully integrated into the germline, driving strong ubiquitous expression of eGFP in the first transgenic Midas cichlid line. Additionally, we show transient expression of two further transgenic constructs, ubiquitin::tdTomato and mitfa::eGFP. Transgenesis in Midas cichlids will facilitate further investigation of the genetic basis of species-specific traits, many of which are adaptations. Transgenesis is a versatile tool not only for studying regulatory elements such as promoters and enhancers, but also for testing gene function through overexpression of allelic gene variants. As such, it is an important first step in establishing the Midas cichlid as a powerful model for studying adaptive coding and non-coding changes in an ecological and evolutionary context.

  2. DISTINCT ROLES OF β1 MIDAS, ADMIDAS AND LIMBS CATION-BINDING SITES IN LIGAND RECOGNITION BY INTEGRIN α2β1*

    Science.gov (United States)

    Valdramidou, Dimitra; Humphries, Martin J.; Mould, A. Paul

    2012-01-01

    Integrin-ligand interactions are regulated in a complex manner by divalent cations, and previous studies have identified ligand-competent, stimulatory, and inhibitory cation-binding sites. In collagen-binding integrins, such as α2β1, ligand recognition takes place exclusively at the α subunit I domain. However, activation of the αI domain depends on its interaction with a structurally similar domain in the β subunit known as the I-like or βI domain. The top face of the βI domain contains three cation-binding sites: the metal-ion dependent adhesion site (MIDAS), the ADMIDAS (adjacent to MIDAS) and LIMBS (ligand-associated metal binding site). The role of these sites in controlling ligand binding to the αI domain has yet to be elucidated. Mutation of the MIDAS or LIMBS completely blocked collagen binding to α2β1; in contrast mutation of the ADMIDAS reduced ligand recognition but this effect could be overcome by the activating mAb TS2/16. Hence, the MIDAS and LIMBS appear to be essential for the interaction between αI and βI whereas occupancy of the ADMIDAS has an allosteric effect on the conformation of βI. An activating mutation in the α2 I domain partially restored ligand binding to the MIDAS and LIMBS mutants. Analysis of the effects of Ca2+, Mg2+ and Mn2+ on ligand binding to these mutants showed that the MIDAS is a ligand-competent site through which Mn2+ stimulates ligand binding, whereas the LIMBS is a stimulatory Ca2+-binding site, occupancy of which increases the affinity of Mg2+ for the MIDAS. PMID:18820259

  3. Prazdniki i budni "Tjomnõhh notshei" / Eteri Kekelidze

    Index Scriptorium Estoniae

    Kekelidze, Eteri, 1944-

    2006-01-01

    10. Pimedate Ööde Filmifestival avatakse esilinastusega : James Tusty ja Maureen Castle Tusty dokumentaalfilm Eestist "Laulev revolutsioon" ("Singing Revolution"). Lühiülevaade festivali filmiprogrammidest, üritustest ja Venemaa filmidest, mida festivalil näha saab

  4. Retrospective evaluation of exposure index (EI) values from plain radiographs reveals important considerations for quality improvement

    International Nuclear Information System (INIS)

    Mothiram, Ursula; Brennan, Patrick C; Robinson, John; Lewis, Sarah J; Moran, Bernadette

    2013-01-01

    Following X-ray exposure, radiographers receive immediate feedback on detector exposure in the form of the exposure index (EI). To identify whether radiographers are meeting manufacturer-recommended EI (MREI) ranges for routine chest, abdomen and pelvis X-ray examinations under a variety of conditions and to examine factors affecting the EI. Data on 5000 adult X-ray examinations including the following variables were collected: examination parameters, EI values, patient gender, date of birth, date and time of examination, grid usage and the presence of implant or prosthesis. Descriptive statistics were used to summarize each data set and the Mann–Whitney U test was used to determine significant differences, with P < 0.05 indicating significance for all tests. Most examinations demonstrated EI values that were outside the MREI ranges, with significantly higher median EI values recorded for female patient radiographs than those for male patients for all manufacturers, indicating higher detector exposures for all units except for Philips digital radiography (DR), where increased EI values indicate lower exposure (P = 0.01). Median EI values for out of hours radiography were also significantly higher compared with normal working hours for all technologies (P ≤ 0.02). Significantly higher median EI values were demonstrated for Philips DR chest X-rays without as compared to those with the employment of a grid (P = 0.03), while significantly lower median EI values were recorded for Carestream Health computed radiography (CR) chest X-rays when an implant or prosthesis was present (P = 0.02). Non-adherence to MREIs has been demonstrated with EI value discrepancies being dependent on patient gender, time/day of exposure, grid usage and the presence of an implant or prosthesis. Retrospective evaluation of EI databases is a valuable tool to assess the need of quality improvement in routine DR

  5. Retrospective evaluation of exposure index (EI) values from plain radiographs reveals important considerations for quality improvement

    Energy Technology Data Exchange (ETDEWEB)

    Mothiram, Ursula; Brennan, Patrick C; Robinson, John; Lewis, Sarah J [Medical Imaging Optimisation and Perception Group (MIOPeG), Discipline of Medical Radiation Sciences, Faculty of Health Science, University of Sydney, Sydney (Australia); Moran, Bernadette [Department of Clinical Medicine, Trinity College Dublin, Dublin (Ireland); Medical Imaging Optimisation and Perception Group (MIOPeG), Discipline of Medical Radiation Sciences, Faculty of Health Science, University of Sydney, Sydney (Australia)

    2013-12-15

    Following X-ray exposure, radiographers receive immediate feedback on detector exposure in the form of the exposure index (EI). To identify whether radiographers are meeting manufacturer-recommended EI (MREI) ranges for routine chest, abdomen and pelvis X-ray examinations under a variety of conditions and to examine factors affecting the EI. Data on 5000 adult X-ray examinations including the following variables were collected: examination parameters, EI values, patient gender, date of birth, date and time of examination, grid usage and the presence of implant or prosthesis. Descriptive statistics were used to summarize each data set and the Mann–Whitney U test was used to determine significant differences, with P < 0.05 indicating significance for all tests. Most examinations demonstrated EI values that were outside the MREI ranges, with significantly higher median EI values recorded for female patient radiographs than those for male patients for all manufacturers, indicating higher detector exposures for all units except for Philips digital radiography (DR), where increased EI values indicate lower exposure (P = 0.01). Median EI values for out of hours radiography were also significantly higher compared with normal working hours for all technologies (P ≤ 0.02). Significantly higher median EI values were demonstrated for Philips DR chest X-rays without as compared to those with the employment of a grid (P = 0.03), while significantly lower median EI values were recorded for Carestream Health computed radiography (CR) chest X-rays when an implant or prosthesis was present (P = 0.02). Non-adherence to MREIs has been demonstrated with EI value discrepancies being dependent on patient gender, time/day of exposure, grid usage and the presence of an implant or prosthesis. Retrospective evaluation of EI databases is a valuable tool to assess the need of quality improvement in routine DR.

  6. The scanning mechanism for ROSETTA/MIDAS: from an engineering model to the flight model

    Science.gov (United States)

    Le Letty, R.; Barillot, F.; Lhermet, N.; Claeyssen, F.; Yorck, M.; Gavira Izquierdo, J.; Arends, H.

    2001-09-01

    The MIDAS (Micro Imaging Dust Analysis System) instrument jointly developed by IWF Graz (AT) and the Solar Space Division of ESA/ESTEC (NL) will flow on ROSETTA and will analyse the dust of the 46P/Wirtanen comet using an Atomic Force Microscope (AFM). A piezoelectric XYZ stage, used to scan the sample in 3 axis, is part of the instrument and has been fully designed and qualified under the ESA/ESTEC contract no13090/98/NL/MV. Two qualification models (EQM/QM) and two flight models (FM/FSM) have been integrated and fully tested within 18 months. The basic principle of the stage has been described in a previous paper. The XY stage includes a latch mechanism based on two Shape Memory actuators. This paper focuses on the lessons learned during the qualification campaign, especially on the testing activities and on the latch mechanism. The XYZ stage has followed a full qualification campaign including Thermal Vacuum cycles, Random Vibrations tests and lifetime tests. The latch mechanism has been designed and tested with the following features: easiness of locking and refurbishment operations, compatibility with the parallel two degrees of freedom mechanism, low shock device. It has been tested more than 20 times, including 4 tests in the worst case conditions (eg the most demanding power case at -20°C) and 2 times after a vibration test. The results and the parameters influencing the reproducibility are discussed. The functional performances have been assessed using a dedicated test bench. Comments are made on the measurements techniques used to get results independent from the drift effect displayed by the piezo components. The calibration work (static and gain of the position sensors) have played an important role during the testing activities. Several parameters (temperature, piezo drift effect and external forces acting on the stage and coming from the coarse approach mechanism) affects the static position. Because of the limited stroke range of reading of the

  7. Recommendations for an Executive Information System (EIS) for the NASA Accounting and Financial Information System (NAFIS)

    Science.gov (United States)

    Goss, Ernest Preston

    1991-01-01

    The objectives were to: (1) survey state-of-the-art computing architectures, tools, and technologies for implementing an Executive Information System (EIS); (2) review MSFC capabilities and efforts in developing an EIS for Shuttle Projects Office and the Payloads Project Office; (3) review management reporting requirements for the NASA Accounting and Financial Information System (NAFIS) Project in the areas of cost, schedule, and technical performance, and insure that the EIS fully supports these requirements; and (4) develop and implement a pilot concept for a NAFIS EIS. A summary of the findings of this work is presented.

  8. Planeeringut ei saadud 8 päevaga

    Index Scriptorium Estoniae

    2010-01-01

    Tartu Ringkonnakohtu otsusest Ain Seppiku, Sulev Seppiku ja Siim Seppiku ning ajalehe Äripäev vahel. Äripäev lükkab ümber andmed selle kohta, nagu oleks nn Antennideväljaku krundi detailplaneering kehtestatud 8 päevaga. Vastukaja artiklitele: Soe, Ralf-Martin. Sulev Seppik tegi Viimsis imet. // Äripäev (2007/Mar/1), lk. 4-5 ; Arumäe, Urmas. Viimsi võim ei tegele maaäriga. // Äripäev (2007/Mar/13), lk. 27 ; Soe, Ralf-Martin. Viimsi võtmeisikute tehingutel kahtlane maik. // Äripäev (2007/Mar/23), lk. 12-13

  9. Corrosion behavior of boride layers evaluated by the EIS technique

    Energy Technology Data Exchange (ETDEWEB)

    Campos, I. [Instituto Politecnico Nacional. SEPI-ESIME U.P. Adolfo Lopez Mateos, Zacatenco, Mexico D.F. 07738 (Mexico)], E-mail: icampos@ipn.mx; Palomar-Pardave, M. [Universidad Autonoma Metropolitana-Azcapotzalco, Materials Department, Avenue San Pablo 180 Col. Reynosa Tamaulipas, Mexico D.F. 02200 (Mexico); Amador, A. [Tecnologico de Monterrey, Campus Ciudad de Mexico, Calle del Puente 222 Col. Ejidos de Huipulco, Mexico D.F. 14380 (Mexico); VillaVelazquez, C. [Instituto Politecnico Nacional. SEPI-ESIME U.P. Adolfo Lopez Mateos, Zacatenco, Mexico D.F. 07738 (Mexico); Hadad, J. [Tecnologico de Monterrey, Campus Ciudad de Mexico, Calle del Puente 222 Col. Ejidos de Huipulco, Mexico D.F. 14380 (Mexico)

    2007-09-30

    The corrosion behavior of boride layers at the AISI 304 steel surface is evaluated in the present study. Electrochemical impedance spectroscopy (EIS) technique was used for the evaluation of the polarization resistance at the steel surface, with the aid of AUTOLAB potentiostat. Samples were treated with boron paste thickness of 4 and 5 mm, in the range of temperatures 1123 {<=} T {<=} 1273 K and exposed time of 4 and 6 h. The electrochemical technique employed 10 mV AC with a frequency scan range from 8 kHz to 3 mHz in deaerated 0.1 M NaCl solution. Nyquist diagrams show that the highest values of corrosion resistance are present in the samples borided at the temperature of 1273 K, with treatment time of 4 h and 4 mm of boron paste thickness. The values of corrosion resistance on borided steels are compared with the porosity exhibited in the layers.

  10. Meie julgeolek ei ole automaatselt kindlustatud / Juhan Parts

    Index Scriptorium Estoniae

    Parts, Juhan, 1966-

    2004-01-01

    Ilmunud ka: Nädaline, 7. sept. 2004, lk. 2; Harjumaa, 7. sept. 2004, lk. 2; Järva Teataja, 7. sept. 2004, lk. 2; Lääne Elu, 7. sept. 2004, lk. 2; Sakala, 7. sept. 2004, lk. 2; Virumaa Teataja, 7. sept. 2004, lk. 7; Pärnu Postimees, 7. sept. 2004, lk. 15; Meie Maa, 7. sept. 2004, lk. 2; Vooremaa, 7. sept. 2004, lk. 2; Koit, 7. sept. 2004, lk. 6; Võrumaa Teataja, 7. sept. 2004, lk. 2; Hiiumaa, 7. sept. 2004, lk. 2. Lihula ausambast, selle sobimatusest rahvusvahelisse konteksti, meedia reageeringust. Minevikukäsitluses ei saa toetuda Teise maailmasõja aegsele Saksa armee mundrile, sest demokraatlikus maailmas samastub see natsismiga, tõdeb peaminister.

  11. 1992 Columbia River salmon flow measures Options Analysis/EIS

    International Nuclear Information System (INIS)

    1992-01-01

    This Options Analysis/Environmental Impact Statement (OA/EIS) identifies, presents effects of, and evaluates the potential options for changing instream flow levels in efforts to increase salmon populations in the lower Columbia and Snake rivers. The potential actions would be implemented during 1992 to benefit juvenile and adult salmon during migration through eight run-of-river reservoirs. The Corps of Engineers (Corps) prepared this document in cooperation with the Bonneville Power Administration and the Bureau of Reclamation. The US Fish and Wildlife Service (FSWS) is a participating agency. The text and appendices of the document describe the characteristics of 10 Federal projects and one private water development project in the Columbia River drainage basin. Present and potential operation of these projects and their effects on the salmon that spawn and rear in the Columbia and Snake River System are presented. The life history, status, and response of Pacific salmon to current environmental conditions are described

  12. 1992 Columbia River Salmon Flow Measures Options Analysis/EIS.

    Energy Technology Data Exchange (ETDEWEB)

    1992-01-01

    This Options Analysis/Environmental Impact Statement (OA/EIS) identifies, presents effects of, and evaluates the potential options for changing instream flow levels in efforts to increase salmon populations in the lower Columbia and Snake rivers. The potential actions would be implemented during 1992 to benefit juvenile and adult salmon during migration through eight run-of-river reservoirs. The Corps of Engineers (Corps) prepared this document in cooperation with the Bonneville Power Administration and the Bureau of Reclamation. The US Fish and Wildlife Service (FSWS) is a participating agency. The text and appendices of the document describe the characteristics of 10 Federal projects and one private water development project in the Columbia River drainage basin. Present and potential operation of these projects and their effects on the salmon that spawn and rear in the Columbia and Snake River System are presented. The life history, status, and response of Pacific salmon to current environmental conditions are described.

  13. Geothermal Exploration Case Studies on OpenEI (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Young, K.; Bennett, M.; Atkins, D.

    2014-03-01

    The U.S. Geological Survey (USGS) resource assessment (Williams et al., 2008) outlined a mean 30 GWe of undiscovered hydrothermal resource in the western United States. One goal of the U.S. Department of Energy's (DOE) Geothermal Technology Office (GTO) is to accelerate the development of this undiscovered resource. DOE has focused efforts on helping industry identify hidden geothermal resources to increase geothermal capacity in the near term. Increased exploration activity will produce more prospects, more discoveries, and more readily developable resources. Detailed exploration case studies akin to those found in oil and gas (e.g. Beaumont and Foster, 1990-1992) will give developers central location for information gives models for identifying new geothermal areas, and guide efficient exploration and development of these areas. To support this effort, the National Renewable Energy Laboratory (NREL) has been working with GTO to develop a template for geothermal case studies on the Geothermal Gateway on OpenEI. In 2012, the template was developed and tested with two case studies: Raft River Geothermal Area (http://en.openei.org/wiki/Raft_River_Geothermal_Area) and Coso Geothermal Area (http://en.openei.org/wiki/Coso_Geothermal_Area). In 2013, ten additional case studies were completed, and Semantic MediaWiki features were developed to allow for more data and the direct citations of these data. These case studies are now in the process of external peer review. In 2014, NREL is working with universities and industry partners to populate additional case studies on OpenEI. The goal is to provide a large enough data set to start conducting analyses of exploration programs to identify correlations between successful exploration plans for areas with similar geologic occurrence models.

  14. A Review of 20 Years of Research on Overdiagnosis and Underdiagnosis in the Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) Project.

    Science.gov (United States)

    Zimmerman, Mark

    2016-02-01

    The Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) project represents an integration of research methodology into a community-based outpatient practice affiliated with an academic medical centre. The MIDAS project is the largest clinical epidemiological study using semi-structured interviews to assess a wide range of psychiatric disorders in a general clinical outpatient practice. In an early report from the MIDAS project, we found that across diagnostic categories clinicians using unstandardized, unstructured clinical interviews underrecognized diagnostic comorbidity, compared with the results of semi-structured interviews. Moreover, we found that the patients often wanted treatment for symptoms of disorders that were diagnosed as comorbid, rather than principal, conditions. This highlighted the importance, from the patient's perspective, of conducting thorough diagnostic interviews to diagnose disorders that are not related to the patient's chief complaint because patients often desire treatment for these additional diagnoses. While several of the initial papers from the MIDAS project identified problems with the detection of comorbid disorders in clinical practice, regarding the diagnosis of bipolar disorder we observed the emergence of an opposite phenomenon-clinician overdiagnosis. The results from the MIDAS project, along with other studies of diagnosis in routine clinical practice, have brought to the forefront the problem with diagnosis in routine clinical practice. An important question is what do these findings suggest about the community standard of care in making psychiatric diagnoses, and whether and how the standard of care should be changed? The implications are discussed. © The Author(s) 2016.

  15. The development of Music in Dementia Assessment Scales (MiDAS)

    Science.gov (United States)

    McDermott, Orii; Orrell, Martin; Ridder, Hanne Mette

    2015-01-01

    There is a need to develop an outcome measure specific to music therapy in dementia that reflects a holistic picture of the therapy process and outcome. This study aimed to develop a clinically relevant and scientifically robust music therapy outcome measure incorporating the values and views of people with dementia. Focus groups and interviews were conducted to obtain qualitative data on what music meant to people with dementia and the observed effects of music. Expert and peer consultations were conducted at each stage of the measure development to maximise its content validity. The new measure was field-tested by clinicians in a care home. Feedback from the clinicians and music therapy experts were incorporated during the review and refinement process of the measure. A review of the existing literature, the experiential results and the consensus process enabled the development of the new outcome measure “Music in Dementia Assessment Scales (MiDAS)”. Analysis of the qualitative data identified five key areas of the impact of music on people with dementia and they were transformed as the five Visual Analogue Scale (VAS) items: levels of Interest, Response, Initiation, Involvement and Enjoyment. MiDAS comprises the five VAS items and a supplementary checklist of notable positive and negative reactions from the individual. This study demonstrates that it is possible to design and develop an easy to apply and rigorous quantitative outcome measure which has a high level of clinical relevance for people with dementia, care home staff and music therapists. PMID:26246670

  16. Morphology and morphometry of the reproductive system of female Saguinus midas (Linnaeus, 1758).

    Science.gov (United States)

    Monteiro, Nathaly Cristine Da Silva; De Lima, Ana Rita; De Carvalho, Ana Flávia; De Carvalho Garcia, Rafael; Therrier, Joanne; Souza, Ana Carla Barros; Pereira, Luiza Correia; Branco, Erika

    2012-06-01

    In this article, the reproductive system's morphology of three young animals of the species Saguinus midas, from the bauxite mine in Paragominas, is described. The specimens were fixed and preserved in a solution of 10% aqueous formaldehyde, followed by dissection, measurement of the genital organs (uterus, vagina, ovaries, and uterine tubes), and histological processing. The vulva is delimited by the labia, with a clitoris. It is lined by keratinized stratified squamous epithelium with sebaceous glands of holocrine secretion. The vagina is an elongated tube with an average length of 26 mm and diameter of 1 mm, presenting a non-keratinized squamous epithelium, disposed between the vestibule of the vagina and cervix, the latter being relatively short. The uterus is simple, has globular shape and is located in the caudal portion of the abdominal cavity, with an average length of 14 mm and average width of 7 mm. It is formed by vascular and serous layers of muscles, and undergoes a bifurcation to form two structures on the bottom of blind sac. The uterine tubes are long and convoluted with an average length of 35 mm (right) and 36 mm (left), consisting of loose connective tissue and muscle layer lined by simple ciliated columnar epithelium. The ovaries are large and ellipsoid with smooth surface. Histologically, one animal showed ovulation fosse. Copyright © 2011 Wiley Periodicals, Inc.

  17. Iodine bonding stabilizes iodomethane in MIDAS pesticide. Theoretical study of intermolecular interactions between iodomethane and chloropicrin.

    Science.gov (United States)

    Glaser, Rainer; Prugger, Kaitlan

    2012-02-22

    The results are reported of a theoretical study of iodomethane (H(3)C-I, 1) and chloropicrin (Cl(3)C-NO(2), 2), of the heterodimers 3-6 formed by aggregation of 1 and 2, and of their addition products 7 and 8 and their possible fragmentation reactions to 9-18. Mixtures of iodomethane and chloropicrin are not expected to show chemistry resulting from their reactions with each other. The structures and stabilities are discussed of the iodine-bonded molecular aggregates (IBMA) 3 and 4 and of the hydrogen- and iodine-bonded molecular aggregates (IHBMA) 5 and 6. The mixed aggregates 3-5 are bound on the free enthalpy surface relative to the homodimers of 1 and 2, and the IBMA structures 3 and 4 are most stable. This result suggests that the mixture of chloropicrin and iodomethane in the pesticide Midas is a good choice to reduce the volatility of iodomethane because of thermodynamically stabilizing iodine bonding.

  18. Direct ECC bypass phenomena in the MIDAS test facility during LBLOCA reflood phase

    International Nuclear Information System (INIS)

    Yun, B. J.; Kweon, T. S.; Ah, D. J.; Ju, I. C.; Song, C. H.; Park, J. K.

    2001-01-01

    This paper describes the experimental results of ECC Direct Bypass Phenomena in the downcomer during the late reflood phase of LBLOCA of the reactor that adopts Direct Vessel Injection as a ECC system. The experiments have been performed in MIDAS test facility using superheated steam and water. The test condition was determined, based on the preliminary analysis of TRAC code, from modified linear scaling method of 1/4.93 length scale. To measure the direct bypass fraction according to the nozzle location, separate effect tests have been performed in case of DVI-4(farthest from broken cold leg) injection, DVI-2(closest to broken cold leg) injection, and DVI-2 and 4 injection, respectively. Also the test was carried out varying the steam flow rate greatly to investigate the effect of steam flow rate on the direct bypass fraction of ECC water. Test results show that the direct bypass fraction of ECC water depends significantly on the injected steam mass flow rate. DVI-4 tests show that the direct bypass fraction increases drastically as the steam flow rate increases. However, in DVI-2 test most of the injected ECC water penetrates into lower downcomer. The direct bypass characteristic in each of DVI-2 and DVI-4 tests is reflected into the direct bypass characteristic curve of DVI-2 and 4 test. The steam condensation reaches to the theoretically allowable maximum value

  19. A 1ST Step Integration of the Restructured MELCOR for the MIDAS Computer Code

    International Nuclear Information System (INIS)

    Park, S. H.; Kim, D. H.; Cho, S. W.

    2006-01-01

    KAERI is developing a localized severe accident code, MIDAS, based on MELCOR. MELCOR uses pointer variables for a fixed-size storage management to save the data. It passes data through two depths, its meaning is not understandable by variable itself. So it is needed to understand the methods for data passing. This method deteriorates the readability, maintainability and portability of the code. As a most important process for a localized severe accident analysis code, it is needed convenient method for data handling. So, it has been used the new features in FORTRAN90 such as a dynamic allocation for the restructuring. The restructuring of the data saving and transferring method of the existing code makes it easy to understand the code. Before an entire restructuring of the code, a restructuring for each package was developed and tested. And then integration of each restructured package was being processed one by one. In this paper, the integrating scope includes the BUR, CF, CVH, DCH, EDF, ESF, MP, SPR, TF and TP packages. As most of them use data within each package and a few packages share data with other packages. The verification was done through comparing the results before and after the restructuring

  20. Aggression and welfare in a common aquarium fish, the Midas cichlid.

    Science.gov (United States)

    Oldfield, Ronald G

    2011-01-01

    Many species of fishes are aggressive when placed in small aquaria. Aggression can negatively affect the welfare of those individuals toward whom it is directed. Animals may behave aggressively in order to defend resources such as food, shelter, mates, and offspring. The decision to defend depends on the distribution of resources and on ecological factors such as number of competitors, amount of available space, and amount of habitat complexity. This study tested the effects of these factors on aggression in a common aquarium fish, the Midas cichlid (Amphilophus citrinellus). The study found that time spent behaving aggressively was not associated with small-scale differences in group size or available space. Aggression was significantly lower in a large aquarium with a complex habitat. Aquaria of sizes typically used in the companion animal (pet) hobby did not provide optimal welfare for cichlids housed with aggressive conspecifics. The public should be aware that this and similar species require larger aquaria with complex habitat, which elicit more natural behavior.

  1. A multimodal interface to resolve the Midas-Touch problem in gaze controlled wheelchair.

    Science.gov (United States)

    Meena, Yogesh Kumar; Cecotti, Hubert; Wong-Lin, KongFatt; Prasad, Girijesh

    2017-07-01

    Human-computer interaction (HCI) research has been playing an essential role in the field of rehabilitation. The usability of the gaze controlled powered wheelchair is limited due to Midas-Touch problem. In this work, we propose a multimodal graphical user interface (GUI) to control a powered wheelchair that aims to help upper-limb mobility impaired people in daily living activities. The GUI was designed to include a portable and low-cost eye-tracker and a soft-switch wherein the wheelchair can be controlled in three different ways: 1) with a touchpad 2) with an eye-tracker only, and 3) eye-tracker with soft-switch. The interface includes nine different commands (eight directions and stop) and integrated within a powered wheelchair system. We evaluated the performance of the multimodal interface in terms of lap-completion time, the number of commands, and the information transfer rate (ITR) with eight healthy participants. The analysis of the results showed that the eye-tracker with soft-switch provides superior performance with an ITR of 37.77 bits/min among the three different conditions (pusers.

  2. "Kui Eesti ütleb gaasitorule ei, võib ka Rootsi öelda ei" / Carl B. Hamilton ; interv. Argo Ideon

    Index Scriptorium Estoniae

    Hamilton, Carl B.

    2007-01-01

    Nord Stream on avaldanud soovi gaasijuhtme teenindusplatvormi rajamiseks Gotlandi juurde. Parlamendiliikme hinnangul peaks Rootsi valitsus ütlema ei nii teenindusplatvormile kui ka gaasitorule. Gaasijuhe on tema sõnul Venemaa projekt

  3. Mart Ustav : me ei pruugi HI-viirusest kunagi vabaneda / Mart Ustav ; interv. Riho Laurisaar

    Index Scriptorium Estoniae

    Ustav, Mart, 1949-

    2006-01-01

    Tartu Ülikooli teadlane Mart Ustav töötab välja HI-viiruse vaktsiini. Kui enamik seniseid aidsiravimeid on keemilised, siis Mart Ustav usub, et on võimalik luua ka looduslik preparaat, mida on lihtne toota ja mis tulevikus võiks abivajajale maksta kõigest mõnisada krooni. Lisaks: Teised Mart Ustavist: Mart Loog, Toivo Maimets

  4. Loeb või ei loe : mis teeb ITst tarbekauba? / Enrique Dans

    Index Scriptorium Estoniae

    Dans, Enrique

    2004-01-01

    Vastukajad ajakirja Think! 2003. aasta 2. numbris avaldatud Nicholas Carr'i artiklile "IT ei loe". Autor ei nõustu enamike N. Carr'i järeldustega IT-st kui tarbekaubast ja esitab IT innovatsiooni kolmetasemelise mudeli

  5. Expanding entrepreneurial, innovative and sustainable (EIS) ecosystems: A cultural-historical activity theory perspective

    NARCIS (Netherlands)

    Audhoe, Romano; Thompson, N.A.; Verduyn, Karen; Leitão, João; Alves, Helena; Krueger, Norris; Park, Jacob

    2018-01-01

    The value of Entrepreneurial, Innovative and Sustainable (EIS) ecosystems has seen increasing recognition from policymakers and researchers alike. Like-minded policymakers employing New Public Management (NPM) understand that the intricate links between diverse EIS stakeholders play a vital role in

  6. Improvisation Theatre Performance as Maintaining and Breaking Cultural Model Narratives. Artiklis uuritakse, kuidas improvisatsiooniteater ja seda žanri harrastavad trupid kannavad edasi teatud tüüpi kultuurilisi narratiive, mida samas mõjutavad reaalsed

    Directory of Open Access Journals (Sweden)

    Reetta Jokinen

    2012-04-01

    Full Text Available Artiklis uuritakse, kuidas improvisatsiooniteater ja seda žanri harrastavad trupid kannavad edasi teatud tüüpi kultuurilisi narratiive, mida samas mõjutavad reaalsed sündmused nii etenduse ruumis kui väljaspool seda. Lähemalt analüüsitakse üht Jyväskyläs tegutseva Improvisatsiooniteatri Joo etendust, selles loodud tegelasi ning nende kaudu esitatavaid kultuurilisi narratiive, milles segunevad erinevad sotsiaalsed, ajaloolised ja müütilised teemad. Kuigi improvisatsiooniteatri ajaloo, meetodite ja eesmärkide kohta on avaldatud palju praktilise kallakuga käsiraamatuid, on seda valdkonda siiski vähe uuritud. Mis tegelikult juhtub, kui inimesed improviseerivad? Teine küsimuste ring on seotud improviseeritud loo temaatika ja dünaamikaga. Improteatri etendus on koht, kus mängitakse simultaanselt läbi mitmeid erinevaid narratiive, kusjuures igal hetkel on iga süžee puhul õhus mitmeid erinevaid arenguvõimalusi, millest mõned on aktuaalsemad kui teised. Need narratiivid võivad ka üksteist kommenteerida või osutada teistele tekstidele, näiteks isegi mõnele nii triviaalsele asjale nagu varem aset leidnud vestlusele. Tekste interpreteeritakse alati suhtes ümbritseva kultuurilise kontekstiga, teiste tekstide ja diskursustega. Artiklis vaadeldakse, kuidas etendajate tehtud valikud kinnistavad või küsitlevad erinevaid kultuurispetsiifilisi stereotüüpseid narratiive, kuidas neid narratiive saaks uutest vaatepunktidest interpreteerida ning kuidas need peegeldavad suhteid trupis. Improetenduses toimuvat ei käsitleta juhuslike sündmustena, vaid kompleksse mõjutuste kogumina, kus etenduse kultuuriline ja esteetiline väljund sõltuvad paljus proovimeetodist, trupi dünaamikast, etendajate unikaalsetest isiklikest narratiividest ja tegeliku elu sündmustest ning laiemast kultuurikontekstist. Improetenduse puhul ei ole kuigi lihtne eristada ühe etendaja valikuid või etenduse pöördepunkte, sest kogu protsess põhineb t

  7. Embryonic and larval development in the Midas cichlid fish species flock (Amphilophus spp.): a new evo-devo model for the investigation of adaptive novelties and species differences.

    Science.gov (United States)

    Kratochwil, Claudius F; Sefton, Maggie M; Meyer, Axel

    2015-02-26

    Central American crater lake cichlid fish of the Midas species complex (Amphilophus spp.) are a model system for sympatric speciation and fast ecological diversification and specialization. Midas cichlids have been intensively analyzed from an ecological and morphological perspective. Genomic resources such as transcriptomic and genomic data sets, and a high-quality draft genome are available now. Many ecologically relevant species-specific traits and differences such as pigmentation and cranial morphology arise during development. Detailed descriptions of the early development of the Midas cichlid in particular, will help to investigate the ontogeny of species differences and adaptations. We describe the embryonic and larval development of the crater lake cichlid, Amphilophus xiloaensis, until seven days after fertilization. Similar to previous studies on teleost development, we describe six periods of embryogenesis - the zygote, cleavage, blastula, gastrula, segmentation, and post-hatching period. Furthermore, we define homologous stages to well-described teleost models such as medaka and zebrafish, as well as other cichlid species such as the Nile tilapia and the South American cichlid Cichlasoma dimerus. Key morphological differences between the embryos of Midas cichlids and other teleosts are highlighted and discussed, including the presence of adhesive glands and different early chromatophore patterns, as well as variation in developmental timing. The developmental staging of the Midas cichlid will aid researchers in the comparative investigation of teleost ontogenies. It will facilitate comparative developmental biological studies of Neotropical and African cichlid fish in particular. In the past, the species flocks of the African Great Lakes have received the most attention from researchers, but some lineages of the 300-400 species of Central American lakes are fascinating model systems for adaptive radiation and rapid phenotypic evolution. The availability

  8. QuBiLS-MIDAS: a parallel free-software for molecular descriptors computation based on multilinear algebraic maps.

    Science.gov (United States)

    García-Jacas, César R; Marrero-Ponce, Yovani; Acevedo-Martínez, Liesner; Barigye, Stephen J; Valdés-Martiní, José R; Contreras-Torres, Ernesto

    2014-07-05

    The present report introduces the QuBiLS-MIDAS software belonging to the ToMoCoMD-CARDD suite for the calculation of three-dimensional molecular descriptors (MDs) based on the two-linear (bilinear), three-linear, and four-linear (multilinear or N-linear) algebraic forms. Thus, it is unique software that computes these tensor-based indices. These descriptors, establish relations for two, three, and four atoms by using several (dis-)similarity metrics or multimetrics, matrix transformations, cutoffs, local calculations and aggregation operators. The theoretical background of these N-linear indices is also presented. The QuBiLS-MIDAS software was developed in the Java programming language and employs the Chemical Development Kit library for the manipulation of the chemical structures and the calculation of the atomic properties. This software is composed by a desktop user-friendly interface and an Abstract Programming Interface library. The former was created to simplify the configuration of the different options of the MDs, whereas the library was designed to allow its easy integration to other software for chemoinformatics applications. This program provides functionalities for data cleaning tasks and for batch processing of the molecular indices. In addition, it offers parallel calculation of the MDs through the use of all available processors in current computers. The studies of complexity of the main algorithms demonstrate that these were efficiently implemented with respect to their trivial implementation. Lastly, the performance tests reveal that this software has a suitable behavior when the amount of processors is increased. Therefore, the QuBiLS-MIDAS software constitutes a useful application for the computation of the molecular indices based on N-linear algebraic maps and it can be used freely to perform chemoinformatics studies. Copyright © 2014 Wiley Periodicals, Inc.

  9. The Effect of External Vessel Cooling for a 2 inch LOCA Severe Accident Scenario at SMART with MIDAS/SMR

    International Nuclear Information System (INIS)

    Park, Jong Hwa; Kim, Dong Ha; Chung, Young Jong; Park, Sun Hee; Cho, Seong Won

    2010-01-01

    KAERI is developing a new concept of reactor that all the main components such as the steam generator, the coolant pumps and the pressurizer are located inside the reactor vessel. This feature may prevent the large size of LOCA. However it is necessary to estimate the hypothetical severe accidents progression for improving the degree of safety and identifying the unknown weakness of the system against an accident. To simulate a hypothetical severe accident for the SMART, we adopt the MIDAS/SMR code which was developed by KAERI

  10. MIDAS-FAST: Design and Validation of a Model-Based Tool to Predict Operator Performance with Robotic Arm Automation

    Science.gov (United States)

    Sebok, Angelia (Principal Investigator); Wickens, Christopher; Gacy, Marc; Brehon, Mark; Scott-Nash, Shelly; Sarter, Nadine; Li, Huiyang; Gore, Brian; Hooey, Becky

    2017-01-01

    The Coalition for Aerospace and Science (CAS) is hosting an exhibition on Capitol Hill on June 14, 2017, to highlight the contributions of CAS members to NASAs portfolio of activities. This exhibition represents an opportunity for an HFES members ground breaking work to be displayed and to build on support within Congress for NASAs human research program including in those areas that are of specific interest to the HFE community. The intent of this poster presentation is to demonstrate the positive outcome that comes from funding HFE related research on a project like the one exemplified by MIDAS-FAST.

  11. Ma tean, mida sa näitad end olevat teinud läinud suvel / Laura Kuusk

    Index Scriptorium Estoniae

    Kuusk, Laura, 1982-

    2006-01-01

    Kuraator Marco Laimre juhendamisel valminud Eesti Kunstiakadeemia III kursuse fotograafiaüliõpilaste suvepraktika tööde näitus "Ma tean, mida sa tegid läinud suvel / I know what you did last summer" Eesti Kunstiakadeemia galeriis kuni 3. X. Helina Kõrmi, Dmitri Gerassimovi, Kristjan-Jaak Tammiksaare, Anne-Mai Pällo, Tuuli Antsovi, Terje Ugandi, Ivar Veermäe, Riika Tauriaineni, Kätly Kaibaldi, Raul Viitungi ja Andrus Kaursoni töödest

  12. Energy Tax versus Carbon Tax. A quantitative macro economical analysis with the HERMES/MIDAS models

    International Nuclear Information System (INIS)

    Karadeloglou, P.

    1992-01-01

    The idea of imposing a tax has been recently put forward as a policy-instrument to induce substitutions aiming at reducing CO[sub 2] overall emissions. One can distinguish two options: recycle tax revenues for energy system restructuring (supply or demand restructuring); or use the corresponding revenues in order to reduce the negative impacts caused on the economic activity by the introduction of the tax. Several papers dealing with only the macroeconomic aspects of the environmental problems have been written. These papers neglect more or less the energy sphere and consider that the energy feedback effects are very small. Macroeconomic impacts of the carbon tax have been examined for the United Kingdom and for the four big European countries elsewhere. In this paper a synthesis of both the energy and the macroeconomic approaches is realized. The approach adopted is global and tries to evaluate the impacts on both the economic and energy system. The main question examined is the effectiveness and impacts of fiscal policy on CO[sub 2] emission and the effects of the adoption of an accommodating policy. Thus, not only the effects of imposing an energy or carbon tax are examined, but also the effects of introducing accommodating measures are studied. The analysis is effected by using the HERMES-MIDAS linked system of models and is limited in analyzing the effects of carbon and energy taxes and the reduction of direct taxes and is effected for four countries namely France, Federal Republic of Germany, Italy and the United Kingdom. In section 2 policy scenarios are described while in sections three and four the results of the policy simulations are presented. In section five we compare the differences of two taxes (energy tax and carbon tax) and in section six the reduction of direct taxation as an accommodating measure is examined. 27 tabs., 10 refs

  13. Constraining Microwave Emission from Extensive Air Showers via the MIDAS Experiment

    Science.gov (United States)

    Richardson, Matthew; Privitera, Paolo

    2017-01-01

    Ultra high energy cosmic rays (UHECRs) are accelerated by the most energetic processes in the universe. Upon entering Earth’s atmosphere they produce particle showers known as extensive air showers (EASs). Observatories like the Pierre Auger Observatory sample the particles and light produced by the EASs through large particle detector arrays or nitrogen fluorescence detectors to ascertain the fundamental properties of UHECRs. The large sample of high quality data provided by the Pierre Auger Observatory can be attributed to the hybrid technique which utilizes the two aforementioned techniques simultaneously; however, the limitation of only being able to observe nitrogen fluorescence from EASs on clear moonless nights yields a limited 10% duty cycle for the hybrid technique. One proposal for providing high quality data at increased statistics is the observation of isotropic microwave emission from EASs, as such emission would be observed with a 100% duty cycle. Measurements of microwave emission from laboratory air plasmas conducted by Gorham et al. (2008) produced promising results indicating that the microwave emission should be observable using inexpensive detectors. The Microwave Detection of Air Showers (MIDAS) experiment was built at the University of Chicago to characterize the isotropic microwave emission from EASs and has collected 359 days of observational data at the location of the Pierre Auger experiment. We have performed a time coincidence analysis between this data and data from Pierre Auger and we report a null result. This result places stringent limits on microwave emission from EASs and demonstrates that the laboratory measurements of Gorham et al. (2008) are not applicable to EASs, thus diminishing the feasibility of using isotropic microwave emission to detect EASs.

  14. MIDA: A Multimodal Imaging-Based Detailed Anatomical Model of the Human Head and Neck.

    Directory of Open Access Journals (Sweden)

    Maria Ida Iacono

    Full Text Available Computational modeling and simulations are increasingly being used to complement experimental testing for analysis of safety and efficacy of medical devices. Multiple voxel- and surface-based whole- and partial-body models have been proposed in the literature, typically with spatial resolution in the range of 1-2 mm and with 10-50 different tissue types resolved. We have developed a multimodal imaging-based detailed anatomical model of the human head and neck, named "MIDA". The model was obtained by integrating three different magnetic resonance imaging (MRI modalities, the parameters of which were tailored to enhance the signals of specific tissues: i structural T1- and T2-weighted MRIs; a specific heavily T2-weighted MRI slab with high nerve contrast optimized to enhance the structures of the ear and eye; ii magnetic resonance angiography (MRA data to image the vasculature, and iii diffusion tensor imaging (DTI to obtain information on anisotropy and fiber orientation. The unique multimodal high-resolution approach allowed resolving 153 structures, including several distinct muscles, bones and skull layers, arteries and veins, nerves, as well as salivary glands. The model offers also a detailed characterization of eyes, ears, and deep brain structures. A special automatic atlas-based segmentation procedure was adopted to include a detailed map of the nuclei of the thalamus and midbrain into the head model. The suitability of the model to simulations involving different numerical methods, discretization approaches, as well as DTI-based tensorial electrical conductivity, was examined in a case-study, in which the electric field was generated by transcranial alternating current stimulation. The voxel- and the surface-based versions of the models are freely available to the scientific community.

  15. Energy Tax versus Carbon Tax. A quantitative macro economical analysis with the HERMES/MIDAS models

    Energy Technology Data Exchange (ETDEWEB)

    Karadeloglou, P. [National Technical University of Athens (Greece)

    1992-03-01

    The idea of imposing a tax has been recently put forward as a policy-instrument to induce substitutions aiming at reducing CO{sub 2} overall emissions. One can distinguish two options: recycle tax revenues for energy system restructuring (supply or demand restructuring); or use the corresponding revenues in order to reduce the negative impacts caused on the economic activity by the introduction of the tax. Several papers dealing with only the macroeconomic aspects of the environmental problems have been written. These papers neglect more or less the energy sphere and consider that the energy feedback effects are very small. Macroeconomic impacts of the carbon tax have been examined for the United Kingdom and for the four big European countries elsewhere. In this paper a synthesis of both the energy and the macroeconomic approaches is realized. The approach adopted is global and tries to evaluate the impacts on both the economic and energy system. The main question examined is the effectiveness and impacts of fiscal policy on CO{sub 2} emission and the effects of the adoption of an accommodating policy. Thus, not only the effects of imposing an energy or carbon tax are examined, but also the effects of introducing accommodating measures are studied. The analysis is effected by using the HERMES-MIDAS linked system of models and is limited in analyzing the effects of carbon and energy taxes and the reduction of direct taxes and is effected for four countries namely France, Federal Republic of Germany, Italy and the United Kingdom. In section 2 policy scenarios are described while in sections three and four the results of the policy simulations are presented. In section five we compare the differences of two taxes (energy tax and carbon tax) and in section six the reduction of direct taxation as an accommodating measure is examined. 27 tabs., 10 refs.

  16. 78 FR 54871 - Notice of Amendment to the Notice of Intent To Prepare an Environmental Impact Statement (EIS...

    Science.gov (United States)

    2013-09-06

    ... alternatives and a ``no action'' alternative in the EIS. An EIS will be prepared to assess the potential social... archeological resources; air and water quality; noise; recreation; land use; and aesthetics. c. The Corps will...

  17. Current source enhancements in Electrical Impedance Spectroscopy (EIS) to cancel unwanted capacitive effects

    Science.gov (United States)

    Zarafshani, Ali; Bach, Thomas; Chatwin, Chris; Xiang, Liangzhong; Zheng, Bin

    2017-03-01

    Electrical Impedance Spectroscopy (EIS) has emerged as a non-invasive imaging modality to detect and quantify functional or electrical properties related to the suspicious tumors in cancer screening, diagnosis and prognosis assessment. A constraint on EIS systems is that the current excitation system suffers from the effects of stray capacitance having a major impact on the hardware subsystem as the EIS is an ill-posed inverse problem which depends on the noise level in EIS measured data and regularization parameter in the reconstruction algorithm. There is high complexity in the design of stable current sources, with stray capacitance reducing the output impedance and bandwidth of the system. To confront this, we have designed an EIS current source which eliminates the effect of stray capacitance and other impacts of the capacitance via a variable inductance. In this paper, we present a combination of operational CCII based on a generalized impedance converter (OCCII-GIC) with a current source. The aim of this study is to use the EIS system as a biomedical imaging technique, which is effective in the early detection of breast cancer. This article begins with the theoretical description of the EIS structure, current source topologies and proposes a current conveyor in application of a Gyrator to eliminate the current source limitations and its development followed by simulation and experimental results. We demonstrated that the new design could achieve a high output impedance over a 3MHz frequency bandwidth when compared to other types of GIC circuits combined with an improved Howland topology.

  18. 77 FR 26025 - Notice of Intent To Prepare a Environmental Impact Statement (EIS) for the HOPE SF Development at...

    Science.gov (United States)

    2012-05-02

    ... a Environmental Impact Statement (EIS) for the HOPE SF Development at Potrero Terrace and Potrero... Statement (EIR/EIS) for the HOPE SF Development at the Potrero Terrace and Potrero Annex Public Housing Development (Potrero HOPE SF Master Plan Project). The EIR/EIS will be a joint National Environmental Policy...

  19. Experimental observation of a multi-dimensional mixing behavior of steam-water flow in the MIDAS test facility

    International Nuclear Information System (INIS)

    Kweon, T. S.; Yun, B. J.; Ah, D. J.; Ju, I. C.; Song, C. H.; Park, J. K.

    2001-01-01

    Multi-dimensional thermal-hydraulic hehavior, such as ECC (Emergency Core Cooling) bypass, ECC penetration, steam-water condensation and accumulated water level, in an annular downcomer of a PWR (Pressurized Water Reactor) reactor vessel with a DVI(Direct Vessel Injection) injection mode is presented based on the experimental observations in the MIDAS (Multi-dimensional Investigation in Downcomer Annulus Simulation) steam-water facility. From the steady-state tests to similate a late reflood phase of LBLOCA (Large Break Loss-of-Coolant Accidents), major thermal-hydraulic phenomena in the downcomer are quantified under a wide range of test conditions. Especially, isothermal lines show well multi-dimensional phenomena of phase interaction between steam and water in the annulus downcomer. Overall test results show that multi-dimensional thermal-hydraulic behaviors occur in the downcomer annulus region as expected. The MIDAS test facility is a steam-water separate effect test facility, which is 1/4.93 linearly scaled-down of a 1400 MWe PWR type of nuclear reactor, with focusing on understanding multi-dimensional thermal-hydraulic phenomena in annulus downcomer with various types of safety injection location during refill or reflood phase of a LBLOCA in PWR

  20. Man-Machine Integration Design and Analysis System (MIDAS) v5: Augmentations, Motivations, and Directions for Aeronautics Applications

    Science.gov (United States)

    Gore, Brian F.

    2011-01-01

    As automation and advanced technologies are introduced into transport systems ranging from the Next Generation Air Transportation System termed NextGen, to the advanced surface transportation systems as exemplified by the Intelligent Transportations Systems, to future systems designed for space exploration, there is an increased need to validly predict how the future systems will be vulnerable to error given the demands imposed by the assistive technologies. One formalized approach to study the impact of assistive technologies on the human operator in a safe and non-obtrusive manner is through the use of human performance models (HPMs). HPMs play an integral role when complex human-system designs are proposed, developed, and tested. One HPM tool termed the Man-machine Integration Design and Analysis System (MIDAS) is a NASA Ames Research Center HPM software tool that has been applied to predict human-system performance in various domains since 1986. MIDAS is a dynamic, integrated HPM and simulation environment that facilitates the design, visualization, and computational evaluation of complex man-machine system concepts in simulated operational environments. The paper will discuss a range of aviation specific applications including an approach used to model human error for NASA s Aviation Safety Program, and what-if analyses to evaluate flight deck technologies for NextGen operations. This chapter will culminate by raising two challenges for the field of predictive HPMs for complex human-system designs that evaluate assistive technologies: that of (1) model transparency and (2) model validation.

  1. CALIFICAREA JURIDICO-PENALĂ A VIOLENŢEI SEXUALE ASUPRA FEMEILOR CA FORMĂ DISTINCTĂ A VIOLENŢEI ÎN FAMILIE

    OpenAIRE

    Nicolae CORCEA

    2016-01-01

    Scopul acestui mesaj ştiinţific constă în rezolvarea controverselor doctrinare în domeniul calificării infracţiunii de violenţă în familie în una din formele ei speciale, cum ar fi violenţa sexuală. Cu toate că violenţa sexuală nu este prevă­zută expres de către legiuitor ca o formă distinctă a violenţei în familie, aceasta devine un fenomen extrem de răspândit. Autorul analizează violenţa împotriva femeilor bazată pe gen, arată caracterul discriminator al violenţei în familie îm­pot­riva fem...

  2. Kus oli sinu firma, kui revolutsioon algas? / Andres Kask

    Index Scriptorium Estoniae

    Kask, Andres

    2013-01-01

    EXPO 2015, Milanos. Maailmanäitus kui üks suuremaid riikidevahelisi kommunikatsiooniüritusi, eesmärgiks jagada konkurentidele ja partneritele teavet olulise kohte osaleva riigi arenguetapis. Eesti paviljonist EXPO-l

  3. Nähtamatu revolutsioon / David R. Smith ; interv. Philip Ball

    Index Scriptorium Estoniae

    Smith, David R.

    2007-01-01

    Tehisstruktuuriga metamaterjalid võivad põhjapanevalt muuta telekommunikatsiooni, andmekandjaid ja isegi päikeseenergeetikat, kinnitab Dukeѫi ülikooli töörühma juht David R. Smith. Artikkel üldpealkirja all: 10 tulevikutehnoloogiat 2007

  4. Dokumentaalfilm "Laulev revolutsioon" tähistab vabadust / Kalev Vilgats

    Index Scriptorium Estoniae

    Vilgats, Kalev

    2007-01-01

    Dokumentalistide James Tusty ja Maureen Castle Tusty Eesti taasiseseisvumisest kõnelevast dokumentaalfilmist kui suurepärasest Eesti tutvustajast maailmale kirjutab oma koduleheküljel USA uuringute firma Media Research Center president L. Brent Bozell III. Refereering

  5. Why does self-reported emotional intelligence predict job performance? A meta-analytic investigation of mixed EI.

    Science.gov (United States)

    Joseph, Dana L; Jin, Jing; Newman, Daniel A; O'Boyle, Ernest H

    2015-03-01

    Recent empirical reviews have claimed a surprisingly strong relationship between job performance and self-reported emotional intelligence (also commonly called trait EI or mixed EI), suggesting self-reported/mixed EI is one of the best known predictors of job performance (e.g., ρ = .47; Joseph & Newman, 2010b). Results further suggest mixed EI can robustly predict job performance beyond cognitive ability and Big Five personality traits (Joseph & Newman, 2010b; O'Boyle, Humphrey, Pollack, Hawver, & Story, 2011). These criterion-related validity results are problematic, given the paucity of evidence and the questionable construct validity of mixed EI measures themselves. In the current research, we update and reevaluate existing evidence for mixed EI, in light of prior work regarding the content of mixed EI measures. Results of the current meta-analysis demonstrate that (a) the content of mixed EI measures strongly overlaps with a set of well-known psychological constructs (i.e., ability EI, self-efficacy, and self-rated performance, in addition to Conscientiousness, Emotional Stability, Extraversion, and general mental ability; multiple R = .79), (b) an updated estimate of the meta-analytic correlation between mixed EI and supervisor-rated job performance is ρ = .29, and (c) the mixed EI-job performance relationship becomes nil (β = -.02) after controlling for the set of covariates listed above. Findings help to establish the construct validity of mixed EI measures and further support an intuitive theoretical explanation for the uncommonly high association between mixed EI and job performance--mixed EI instruments assess a combination of ability EI and self-perceptions, in addition to personality and cognitive ability. PsycINFO Database Record (c) 2015 APA, all rights reserved.

  6. A second horizon scan of biogeography: Golden Ages, Midas touches, and the Red Queen

    Directory of Open Access Journals (Sweden)

    Michael N Dawson

    2016-12-01

    and geography for decades into the future. But golden ages come and go, and they need not touch every domain in a discipline nor affect subdisciplines at the same time; moreover, what appears to be a Golden Age may sometimes have an undesirable ‘Midas touch’. Contexts within and outwith biogeography—e.g., methods, knowledge, climate, biodiversity, politics—are continually changing, and at times it can be challenging to establish or maintain relevance. In so many races with the Red Queen, we suggest that biogeography will enjoy greatest success if we also increasingly engage with the epistemology of our discipline.

  7. Iraani filmimeister ei pääse Berliini festivali žüriisse / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2011-01-01

    10.-20. veebruarini toimuva 61. Berliini rahvusvahelise filmifestivali žüriis ei saa osaleda iraani filmirežissöör Jafar Panahi, kellel on kohtuasi pooleli. Rahvusvahelist žüriid juhib Isabella Rossellini

  8. Väljaöeldut tagasi võtta ei saa / Raivo Uukkivi

    Index Scriptorium Estoniae

    Uukkivi, Raivo, 1962-

    2007-01-01

    Õpetaja suhtumisest õpilasse. Õpetaja professionaalsusest ja tema missioonitundest. Vastukaja artiklile: Krull, Edgar. Kõvad seadused ja politsei ei vabasta kohustusest kasvatada // Õpetajate Leht (2007) 16. veebr., lk. 5. Jüri Gümnaasiumi koolikonfliktist

  9. Aiandusäri jahtumismärke ei ilmuta / Aive Herja

    Index Scriptorium Estoniae

    Herja, Aive

    2008-01-01

    Haljastus- ja aiandusäri praegu veel jahtumismärke ei ilmuta. Arvamust avaldavad aiandusettevõtete juhid. Lk. 28 intervjuu maastikuarhitektuurifirma Artes Terrae OÜ juhatuse liikme Sulev Nurmega "Sulev Nurme: maastikuarhitektuuri turg on kasvutrendis"

  10. Euroopa naabruspoliitika ei ole viisakas äraütlemine / Marianne Mikko

    Index Scriptorium Estoniae

    Mikko, Marianne, 1961-

    2006-01-01

    Euroopa Parlamendi liikme sõnul reageeris europarlament Transnistria rahvahääletusele resolutsiooniga, andes märku, et ei tunnusta separatiste, nende korraldatud rahvahääletusi ega hääletustulemusi

  11. Peaminister Juhan Parts ei plaani ametit maha panna / Juhan Parts ; interv. Toomas Sildam

    Index Scriptorium Estoniae

    Parts, Juhan, 1966-

    2004-01-01

    Peaminister Juhan Parts pooldab paremerakondade ühinemist, ei kavatse ametist lahkuda ning peab valitsuse üheks ülesandeks rahvaarutelu algatamist vabaduse samba üle. Lisa: Ene Ergma kõnest Riigikogus (13.09.2004)

  12. Edgar Savisaar : Mina ei anna mitte mingit hinnangut / Edgar Savisaar ; interv. Dannar Leitmaa, Holger Roonemaa

    Index Scriptorium Estoniae

    Savisaar, Edgar, 1950-

    2008-01-01

    Tallinna linnapea vastused linnavalitsuse pressikonverentsil küsimustele, mis puudutasid Keskerakonna suurrahastaja Oliver Kruuda omavolilist ehitamist Nõmmel. Vt. samas: Holger Roonemaa. Inspektorid ei pannud Kruuda tegevust tähele

  13. Endine turujuht end süüdi ei tunnistanud / Hannes Krause

    Index Scriptorium Estoniae

    Krause, Hannes

    2005-01-01

    Vadim Polishtshuk, keda süüdistatakse koos kahe kaaslasega Mait Metsamaa mõrvaprotsessi peamise tunnistaja ähvardamise ja mõjutamise katses, ei tunnistanud end 19. septembril Tallinna linnakohtus alanud protsessil süüdi

  14. Kultuur isiksuse psühholoogiat ei mõjuta / Tiit Kändler

    Index Scriptorium Estoniae

    Kändler, Tiit, 1948-

    2010-01-01

    Psühholoogia uuemate andmete kohaselt ei sõltu indiviidi seadumus kultuurist, soost, vanusest, haridusest. Eesti psühholoogide Jüri Alliku ja Ann Realo osalusel ajakirjas "Journal Personality and Social Psychology" ilmunud artiklist

  15. Kultuur isiksuse psühholoogiat ei mõjuta / Tiit Kändler

    Index Scriptorium Estoniae

    Kändler, Tiit, 1948-

    2005-01-01

    Psühholoogia uuemate andmete kohaselt ei sõltu indiviidi seadumus kultuurist, soost, vanusest, haridusest. Eesti psühholoogide Jüri Alliku ja Anu Realo osalusel ajakirjas "Journal Personality and Social Psychology" ilmunud artiklist

  16. Eesti põllumajanduspoliitika ja WTO leping ei vasta Eesti rahvuslikele huvidele / Janno Reiljan

    Index Scriptorium Estoniae

    Reiljan, Janno, 1951-2018

    2001-01-01

    Eesti liitus Maailma Kaubandusorganisatsiooniga (WTO) endale ebasoodsatel tingimustel, mis ei võimalda meie põllumajandustoodetel välisturul konkureerida. Tabel: Eesti väliskaubandus põllumajandussaadustega. Autor: ERL. Parlamendisaadik

  17. Eesti majandust ei saa rajada võõrtööjõule / Piret Pert

    Index Scriptorium Estoniae

    Pert, Piret

    2006-01-01

    Eesti Ametiühingute Keskliidu, Teenistujate Ametiliitude Organisatsiooni ja Sotsiaaldemokraatliku Erakonna juhtide kohtumisel leiti, et võõrtööjõud ei ole Eestile lahendus. Harri Taliga, Eiki Nestori ja Kadi Pärnitsa seisukohtadest

  18. Sakslastelt tuumaenergiale selge "ei". Merkel on sunnitud tuumaplaane korrigeerima / Sirje Rank

    Index Scriptorium Estoniae

    Rank, Sirje, 1966-

    2011-01-01

    Ligi 60 aastat Daimleri ja Porsche liidumaal valitsenud kristlikud demokraadid said kohalikel valimistel Baden-Württembergis halvima valimisulemuse alates 1952. aastast ja arvatakse, et Saksamaa kantsler Angela Merkel ei käivitagi enamikku ajutiselt suletud vanemaid tuumareaktoreid

  19. NATO peasekretär : Londoni terror ei peata võitlust terrorismi vastu / Ahto Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Ahto, 1970-

    2005-01-01

    8. juunil Brüsselis toimunud erakorralisest istungist, kus avaldati toetust Suurbritanniale pärast Londoni terrorirünnakut, toimunu laadsed rünnakud ei suuda väärata NATO võitlust terrorismiga kogu maailmas. Lisa: G8 ei lasknud end terrorist kõigutada. Kommenteerivad USA president Georg W. Bush, Venemaa president Vladimir Putin, Austraalia peaminister John Howard, Pariisi linnapea Bertrand Delanoe ja ROK-i president Jacques Rogge

  20. Jack Deverell : NATO ei kao kuhugi / Jack Deverell ; interv. Margus Kolga

    Index Scriptorium Estoniae

    Deverell, Jack

    2005-01-01

    NATO põhjapiirkonna vägede endise juhi arvates võiks NATO olla endiselt peamine sõjalise jõu instrument, olgu tegemis siis NATO või EL-i juhitud sõjalise operatsiooniga, ta ei usu, et NATO ja EL muutuvad sõjaliselt ning poliitiliselt omavahel võistlevateks organisatsioonideks. Riigid peaksid tegutsema koos selliste sõjaliste võimete loomisel, milleks nad üksi suutelised ei ole

  1. Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis

    Energy Technology Data Exchange (ETDEWEB)

    Garzan, Atefeh; Willby, Melisa J.; Green, Keith D.; Gajadeera, Chathurada S.; Hou, Caixia; Tsodikov, Oleg V.; Posey, James E.; Garneau-Tsodikova, Sylvie

    2016-12-08

    A two-drug combination therapy where one drug targets an offending cell and the other targets a resistance mechanism to the first drug is a time-tested, yet underexploited approach to combat or prevent drug resistance. By high-throughput screening, we identified a sulfonamide scaffold that served as a pharmacophore to generate inhibitors of Mycobacterium tuberculosis acetyltransferase Eis, whose upregulation causes resistance to the aminoglycoside (AG) antibiotic kanamycin A (KAN) in Mycobacterium tuberculosis. Rational systematic derivatization of this scaffold to maximize Eis inhibition and abolish the Eis-mediated KAN resistance of M. tuberculosis yielded several highly potent agents. A crystal structure of Eis in complex with one of the most potent inhibitors revealed that the inhibitor bound Eis in the AG-binding pocket held by a conformationally malleable region of Eis (residues 28–37) bearing key hydrophobic residues. These Eis inhibitors are promising leads for preclinical development of innovative AG combination therapies against resistant TB.

  2. Kui seda mammit seal jalus ei oleks... / Indrek Pajo, Heiti Riisberg, Jaana Liigand... [jt.

    Index Scriptorium Estoniae

    2010-01-01

    Küsimusele, mida peaks noor keskjuht juhtimise osas tegema kui tunneb pärast paarikuist töötamist üha rohkem, et mõned tema alluvad, kes on temast oluliselt vanemad, töötavad talle vastu, vastavad endine Cleaner Ehitus vanemobjektijuht Indrek Pajo, Trigon Kapital pensioni- ja aktsiafondide eest hoolitsev Heiti Riisberg, konsultatsioonifirma Arikano omanik ja juht Jaana Liigand, Pharmadule OÜ personali- ja büroojuht Helen Neeve, Saku Õlletehase brändide Rock ja Carlsberg juht Karin Golubev ning Kaamos Kinnisvara juht Priit Uustulnd

  3. A Validated Set of MIDAS V5 Task Network Model Scenarios to Evaluate Nextgen Closely Spaced Parallel Operations Concepts

    Science.gov (United States)

    Gore, Brian Francis; Hooey, Becky Lee; Haan, Nancy; Socash, Connie; Mahlstedt, Eric; Foyle, David C.

    2013-01-01

    The Closely Spaced Parallel Operations (CSPO) scenario is a complex, human performance model scenario that tested alternate operator roles and responsibilities to a series of off-nominal operations on approach and landing (see Gore, Hooey, Mahlstedt, Foyle, 2013). The model links together the procedures, equipment, crewstation, and external environment to produce predictions of operator performance in response to Next Generation system designs, like those expected in the National Airspaces NextGen concepts. The task analysis that is contained in the present report comes from the task analysis window in the MIDAS software. These tasks link definitions and states for equipment components, environmental features as well as operational contexts. The current task analysis culminated in 3300 tasks that included over 1000 Subject Matter Expert (SME)-vetted, re-usable procedural sets for three critical phases of flight; the Descent, Approach, and Land procedural sets (see Gore et al., 2011 for a description of the development of the tasks included in the model; Gore, Hooey, Mahlstedt, Foyle, 2013 for a description of the model, and its results; Hooey, Gore, Mahlstedt, Foyle, 2013 for a description of the guidelines that were generated from the models results; Gore, Hooey, Foyle, 2012 for a description of the models implementation and its settings). The rollout, after landing checks, taxi to gate and arrive at gate illustrated in Figure 1 were not used in the approach and divert scenarios exercised. The other networks in Figure 1 set up appropriate context settings for the flight deck.The current report presents the models task decomposition from the tophighest level and decomposes it to finer-grained levels. The first task that is completed by the model is to set all of the initial settings for the scenario runs included in the model (network 75 in Figure 1). This initialization process also resets the CAD graphic files contained with MIDAS, as well as the embedded

  4. Keegi ei võta meilt unistusi, kui me ise neid endalt ei võta / Toomas Hendrik Ilves

    Index Scriptorium Estoniae

    Ilves, Toomas Hendrik, 1953-

    2008-01-01

    Vabariigi Presidendi kõne Eesti Vabariigi väljakuulutamise 90. aastapäeval 24. veebruaril 2008 Estonia teatris. Ilmunud ka: Postimees : na russkom jazõke 25. veebr. 2008, lk. 9; Eesti Päevaleht 25. veebr. 2008, lk. 2, pealk.: Ilves: ärme ajame segamini iseseisvust ja vabadust (lüh.); SL Õhtuleht 25. veebr. 2008, lk. 11, pealk.: Eesti on tugevam kui varem (lüh.) SL Õhtulehes vt. ka juhtkiri: Otsene kõne. SL Õhtulehe arvates oli presidendi kõne lihtne ja selge jutt Eesti kodanikule, heale sõbrale. SL Õhtulehes vt. ka Andres Varustini karikatuur; Pärnu Postimees 26. veebr. 2008, lk. 21, pealk.: Vabariigi presidendi Toomas Hendrik Ilvese aastapäevakõne 24. veebruaril Estonia teatris (lüh.); Hiiu Leht 26. veebr. 2008, lk. 2, pealk.: EV 90. aastapäeva peokõne (lüh.); Järva Teataja 26. veebr. 2008, lk. 2, pealk.: Soovid tuleb täita kuldkalakese abita; Virumaa Teataja 26. veebr. 2008, lk. 4, pealk.: Riigi heaolu eest peab seisma iga kodanik (lüh.); Põhjarannik 26. veebr. 2008, lk. 4, pealk.: Keskendugem jäävale! (lüh.); Severnoje Poberežje 26. veebr. 2008, lk. 4; Sakala 26. veebr. 2008, k. 2, pealk.: Mõisa köis ei lohise enam, sest mõis on oma ja köis on oma (lüh.); Maaleht 28. veebr. 2008, lk. 17, pealk.: Miski pole võimatu, kuni pole tõestatud vastupidist (lüh.); Eesti Elu 29. veebr. 2008, lk. 2, 16, pealk.: Vabariigi President Eesti Vabariigi väljakuulutamise 90. aastapäeval 24. veebruaril 2008 Estonia teatris (lüh.); Vaba Eesti Sõna 28. veebr. 2008, lk. 3, 10, pealk.: Vabariigi Presidendi kõne Eesti Vabariigi väljakuulutamise 90. aastapäeva pidulikul kontsertaktusel 24. veebruaril 2008 Estonia teatris; Vaba Eesti Sõna 13. märts 2008, lk. 12, pealk.: "We have assumed respectable responsibility in the family of nations" (lüh.); Läänekaare Postipoiss 2008, nr. 212, lk. 8-11, pealk.: Vabariigi President Eesti Vabariigi väljakuulutamise 90. aastapäeva pidulikul kontsertaktusel 24. veebruaril 2008 Estonia teatris

  5. Fully automated rodent brain MR image processing pipeline on a Midas server: from acquired images to region-based statistics.

    Science.gov (United States)

    Budin, Francois; Hoogstoel, Marion; Reynolds, Patrick; Grauer, Michael; O'Leary-Moore, Shonagh K; Oguz, Ipek

    2013-01-01

    Magnetic resonance imaging (MRI) of rodent brains enables study of the development and the integrity of the brain under certain conditions (alcohol, drugs etc.). However, these images are difficult to analyze for biomedical researchers with limited image processing experience. In this paper we present an image processing pipeline running on a Midas server, a web-based data storage system. It is composed of the following steps: rigid registration, skull-stripping, average computation, average parcellation, parcellation propagation to individual subjects, and computation of region-based statistics on each image. The pipeline is easy to configure and requires very little image processing knowledge. We present results obtained by processing a data set using this pipeline and demonstrate how this pipeline can be used to find differences between populations.

  6. Can a Point-of-Care Troponin I Assay be as Good as a Central Laboratory Assay? A MIDAS Investigation.

    Science.gov (United States)

    Peacock, W Frank; Diercks, Deborah; Birkhahn, Robert; Singer, Adam J; Hollander, Judd E; Nowak, Richard; Safdar, Basmah; Miller, Chadwick D; Peberdy, Mary; Counselman, Francis; Chandra, Abhinav; Kosowsky, Joshua; Neuenschwander, James; Schrock, Jon; Lee-Lewandrowski, Elizabeth; Arnold, William; Nagurney, John

    2016-09-01

    We aimed to compare the diagnostic accuracy of the Alere Triage Cardio3 Tropinin I (TnI) assay (Alere, Inc., USA) and the PathFast cTnI-II (Mitsubishi Chemical Medience Corporation, Japan) against the central laboratory assay Singulex Erenna TnI assay (Singulex, USA). Using the Markers in the Diagnosis of Acute Coronary Syndromes (MIDAS) study population, we evaluated the ability of three different assays to identify patients with acute myocardial infarction (AMI). The MIDAS dataset, described elsewhere, is a prospective multicenter dataset of emergency department (ED) patients with suspected acute coronary syndrome (ACS) and a planned objective myocardial perfusion evaluation. Myocardial infarction (MI) was diagnosed by central adjudication. The C-statistic with 95% confidence intervals (CI) for diagnosing MI by using a common population (n=241) was 0.95 (0.91-0.99), 0.95 (0.91-0.99), and 0.93 (0.89-0.97) for the Triage, Singulex, and PathFast assays, respectively. Of samples with detectable troponin, the absolute values had high Pearson (R(P)) and Spearman (R(S)) correlations and were R(P)=0.94 and R(S)=0.94 for Triage vs Singulex, R(P)=0.93 and R(S)=0.85 for Triage vs PathFast, and R(P)=0.89 and R(S)=0.73 for PathFast vs Singulex. In a single comparative population of ED patients with suspected ACS, the Triage Cardio3 TnI, PathFast, and Singulex TnI assays provided similar diagnostic performance for MI.

  7. UNDERFLIGHT CALIBRATION OF SOHO/CDS AND HINODE/EIS WITH EUNIS-07

    Energy Technology Data Exchange (ETDEWEB)

    Wang Tongjiang; Brosius, Jeffrey W. [Institute for Astrophysics and Computational Sciences (IACS) in the Department of Physics, Catholic University of America, 620 Michigan Avenue NE, Washington, DC 20064 (United States); Thomas, Roger J.; Rabin, Douglas M.; Davila, Joseph M. [NASA Goddard Space Flight Center, Code 671, Greenbelt, MD 20771 (United States); Young, Peter R. [College of Science, George Mason University, 4400 University Drive, Fairfax, VA 22030 (United States); Del Zanna, Giulio, E-mail: tongjiang.wang@nasa.gov [DAMTP, Centre for Mathematical Sciences, University of Cambridge, Wilberforce Road, Cambridge, CB3 0WA (United Kingdom)

    2011-12-01

    Flights of Goddard Space Flight Center's Extreme Ultraviolet Normal Incidence Spectrograph (EUNIS) sounding rocket in 2006 and 2007 provided updated radiometric calibrations for Solar and Heliospheric Observatory/Coronal Diagnostic Spectrometer (SOHO/CDS) and Hinode/Extreme Ultraviolet Imaging Spectrometer (Hinode/EIS). EUNIS carried two independent imaging spectrographs covering wavebands of 300-370 A in first order and 170-205 A in second order. After each flight, end-to-end radiometric calibrations of the rocket payload were carried out in the same facility used for pre-launch calibrations of CDS and EIS. During the 2007 flight, EUNIS, SOHO/CDS, and Hinode/EIS observed the same solar locations, allowing the EUNIS calibrations to be directly applied to both CDS and EIS. The measured CDS NIS 1 line intensities calibrated with the standard (version 4) responsivities with the standard long-term corrections are found to be too low by a factor of 1.5 due to the decrease in responsivity. The EIS calibration update is performed in two ways. One uses the direct calibration transfer of the calibrated EUNIS-07 short wavelength (SW) channel. The other uses the insensitive line pairs, in which one member was observed by the EUNIS-07 long wavelength (LW) channel and the other by EIS in either the LW or SW waveband. Measurements from both methods are in good agreement, and confirm (within the measurement uncertainties) the EIS responsivity measured directly before the instrument's launch. The measurements also suggest that the EIS responsivity decreased by a factor of about 1.2 after the first year of operation (although the size of the measurement uncertainties is comparable to this decrease). The shape of the EIS SW response curve obtained by EUNIS-07 is consistent with the one measured in laboratory prior to launch. The absolute value of the quiet-Sun He II 304 A intensity measured by EUNIS-07 is consistent with the radiance measured by CDS NIS in quiet regions

  8. Determined of Rainfall Erosivity Indices (EI30, Lal, Hudson and Onchev for Namak Lake Basin

    Directory of Open Access Journals (Sweden)

    Z.T. Alipour

    2011-06-01

    Full Text Available In this research the indices EI30, AIm,‎ KE>1‎ as well as P/√t‎ were determined for 16 pluviograph as well as for 3 Namak Lake Basin nearby stations. Regression relationships were established between the dependent variables of EI30, AIm, KE>1‎ as well as P/√t‎ Indices and other easily accessible rainfall indices of: fournier, modified fournier, maximum monthly rainfall, maximum daily rainfall, standard deviation of monthly and annual rainfall as well as pluviometer site elevations. This made the establishment of appropriate relationships between rainfall intensity dependent indices and the dependent variable of rainfall intensity (at stations where intensity was non-existent possible. In the next step, the indices as well as easily accessible rainfall data from pluviograph stations were exploited to find out EI30 ,AIm ,‎ KE>1‎ as well as P/√t‎ indices, while using the previously obtained regression relationships.

  9. The Application of the EIS in Li-ion Batteries Measurement

    Science.gov (United States)

    Zhai, N. S.; Li, M. W.; Wang, W. L.; Zhang, D. L.; Xu, D. G.

    2006-10-01

    The measurement and determination of the lithium ion battery's electrochemical impedance spectroscopy (EIS) and the application of EIS to battery classification are researched in this paper. The lithium ion battery gets extensive applications due to its inherent advantages over other batteries. For proper and sustainable performance, it is very necessary to check the uniformity of the lithium ion batteries. In this paper, the equivalent circuit of the lithium ion battery is analyzed; the design of hardware circuit based on DSP and software that calculates the EIS of the lithium ion battery is critically done and evaluated. The parameters of the lithium ion equivalent circuit are determined, the parameter values of li-ion equivalent circuit are achieved by least square method, and the application of Principal Component Analysis (CPA) to the battery classification is analyzed.

  10. The Application of the EIS in Li-ion Batteries Measurement

    Energy Technology Data Exchange (ETDEWEB)

    Zhai, N S [Shenzhen Graduate School, Harbin Institute of Technology, Shenzhen (China); Li, M W [Shenzhen Graduate School, Harbin Institute of Technology, Shenzhen (China); Wang, W L [Shenzhen BPL instrument Ltd., Shenzhen (China); Zhang, D L [Shenzhen Graduate School, Harbin Institute of Technology, Shenzhen (China); Xu, D G [Electrical Engineering and Automation School, Harbin Institute of Technology, Harbin (China)

    2006-10-15

    The measurement and determination of the lithium ion battery's electrochemical impedance spectroscopy (EIS) and the application of EIS to battery classification are researched in this paper. The lithium ion battery gets extensive applications due to its inherent advantages over other batteries. For proper and sustainable performance, it is very necessary to check the uniformity of the lithium ion batteries. In this paper, the equivalent circuit of the lithium ion battery is analyzed; the design of hardware circuit based on DSP and software that calculates the EIS of the lithium ion battery is critically done and evaluated. The parameters of the lithium ion equivalent circuit are determined, the parameter values of li-ion equivalent circuit are achieved by least square method, and the application of Principal Component Analysis (CPA) to the battery classification is analyzed.

  11. Interface Design for CMOS-Integrated Electrochemical Impedance Spectroscopy (EIS Biosensors

    Directory of Open Access Journals (Sweden)

    Arjang Hassibi

    2012-10-01

    Full Text Available Electrochemical Impedance Spectroscopy (EIS is a powerful electrochemical technique to detect biomolecules. EIS has the potential of carrying out label-free and real-time detection, and in addition, can be easily implemented using electronic integrated circuits (ICs that are built through standard semiconductor fabrication processes. This paper focuses on the various design and optimization aspects of EIS ICs, particularly the bio-to-semiconductor interface design. We discuss, in detail, considerations such as the choice of the electrode surface in view of IC manufacturing, surface linkers, and development of optimal bio-molecular detection protocols. We also report experimental results, using both macro- and micro-electrodes to demonstrate the design trade-offs and ultimately validate our optimization procedures.

  12. Interface design for CMOS-integrated Electrochemical Impedance Spectroscopy (EIS) biosensors.

    Science.gov (United States)

    Manickam, Arun; Johnson, Christopher Andrew; Kavusi, Sam; Hassibi, Arjang

    2012-10-29

    Electrochemical Impedance Spectroscopy (EIS) is a powerful electrochemical technique to detect biomolecules. EIS has the potential of carrying out label-free and real-time detection, and in addition, can be easily implemented using electronic integrated circuits (ICs) that are built through standard semiconductor fabrication processes. This paper focuses on the various design and optimization aspects of EIS ICs, particularly the bio-to-semiconductor interface design. We discuss, in detail, considerations such as the choice of the electrode surface in view of IC manufacturing, surface linkers, and development of optimal bio-molecular detection protocols. We also report experimental results, using both macro- and micro-electrodes to demonstrate the design trade-offs and ultimately validate our optimization procedures.

  13. The Application of the EIS in Li-ion Batteries Measurement

    International Nuclear Information System (INIS)

    Zhai, N S; Li, M W; Wang, W L; Zhang, D L; Xu, D G

    2006-01-01

    The measurement and determination of the lithium ion battery's electrochemical impedance spectroscopy (EIS) and the application of EIS to battery classification are researched in this paper. The lithium ion battery gets extensive applications due to its inherent advantages over other batteries. For proper and sustainable performance, it is very necessary to check the uniformity of the lithium ion batteries. In this paper, the equivalent circuit of the lithium ion battery is analyzed; the design of hardware circuit based on DSP and software that calculates the EIS of the lithium ion battery is critically done and evaluated. The parameters of the lithium ion equivalent circuit are determined, the parameter values of li-ion equivalent circuit are achieved by least square method, and the application of Principal Component Analysis (CPA) to the battery classification is analyzed

  14. Development and performance evaluation of 32-channel gamma densitometer for the measurement of flow pattern and void fraction in the downcomer of MIDAS test facility

    International Nuclear Information System (INIS)

    Chu, In Cheol; Kim, Y. K.; Yun, B. J.; Kwon, T. S.; Euh, D. J.; Song, C.

    2002-03-01

    APR 1400, which adopts DVI type of ECCS, is expected to show its unique thermal hydraulic phenomena. Therefore, it is necessary to investigate whether existing safety analysis code can correctly predict the thermal hydraulic phenomena. Among the several phenomena, void fraction and flow pattern govern the other major phenomena. Therefore, the main objective of the present study is to develop the 32-channel gamma densitometer which can measure the void fraction and flow pattern in the downcomer at various locations. The 32-channel gamma densitometer for MIDAS test apparatus has been developed. Throughout the performance evaluation test, the integrity of the 32 channel gamma densitometer has been validated. The measurement error of water film thickness is expected to be less than ±0.5mm. Also, it can correctly predict the flow patterns and the transition location of flow pattern in the downcomer of MIDAS test apparatus

  15. 75 FR 26739 - Notice of Intent To Prepare an Environmental Impact Statement (EIS) for Airfield Operations at...

    Science.gov (United States)

    2010-05-12

    ..., Naval Facilities Engineering Command Southeast, 904-542-6866. SUPPLEMENTARY INFORMATION: The Navy's... period (ending June 10, 2010) will receive the same attention and consideration during EIS preparation...

  16. 78 FR 17653 - Upper Great Plains Wind Energy Draft Programmatic Environmental Impact Statement (DOE/EIS-0408)

    Science.gov (United States)

    2013-03-22

    ... Wildlife Service Upper Great Plains Wind Energy Draft Programmatic Environmental Impact Statement (DOE/EIS... Plains Wind Energy Draft Programmatic Environmental Impact Statement (Draft [[Page 17654

  17. THE IMPROVEMENT AND APPLICATION OF EI-GUN (ELECTRICAL INSEMINATION GUN FOR ARTIFICIAL INSEMINATION (AI USING GOAT FRESH SEMEN

    Directory of Open Access Journals (Sweden)

    Mirsa Ita Dewi

    2017-03-01

    Full Text Available Electrical Insemination Gun (EI-GUN was a tool for Artificial Insemination (AI using fresh semen with an electric control system. The research objective was to produced EI-GUN for AI using fresh semen on small ruminants (goat. The research was conducted from March to June 2015. The process of EI-GUN creation implemented in Design and Prototype Laboratory and Aero Modeling Research Laboratory at Engineering Faculty, University of Brawijaya (UB. Testing tools EI-GUN on goat was conducted in the Sumber Sekar Laboratory, Animal Husbandry Faculty, UB.  The methods of research were literature study, tool specification determination, designing EI-GUN, running test, semen evaluation passed EI-GUN and application on Goat. EI-GUN has seven important parts, which supports each other in this operating system. Those parts consist of stylet, servo, system controlled, insemination pump, connecting rod, battery, and holder. EI-GUN work system sucked the semen into insemination pump as much as 5 ml, and release the semen 0.25 ml appropriate standard of AI. It was applicable for 20 times AI. The results showed that the cell motility of spermatozoa ≥ 70% were still in ranging of Indonesian National Standard (SNI.   Keywords: artificial insemination, EI-GUN, fresh semen.

  18. Determined of Rainfall Erosivity Indices (EI30, Lal, Hudson and Onchev) for Namak Lake Basin

    OpenAIRE

    Z.T. Alipour; M.H. Mahdian; S. Hakimkhani; M. Saeedi

    2011-01-01

    In this research the indices EI30, AIm,‎ KE>1‎ as well as P/√t‎ were determined for 16 pluviograph as well as for 3 Namak Lake Basin nearby stations. Regression relationships were established between the dependent variables of EI30, AIm, KE>1‎ as well as P/√t‎ Indices and other easily accessible rainfall indices of: fournier, modified fournier, maximum monthly rainfall, maximum daily rainfall, standard deviation of monthly and annual rainfall as well as pluviometer site elevations. This made ...

  19. Design and analysis of EI core structured transverse flux linear reluctance actuator

    OpenAIRE

    FENERCİOĞLU, AHMET; AVŞAR, YUSUF

    2015-01-01

    In this study, an EI core linear actuator is proposed for horizontal movement systems. It is a transverse flux linear switched reluctance motor designed with an EI core structure geometrically. The actuator is configured into three phases and at a 6/4 pole ratio, and it has a stationary active stator along with a sliding passive translator. The stator consists of E cores and the translator consists of I cores. The actuator has a yokeless design because the stator and translator have no back i...

  20. Tony Blair ei saanud Balti riikidelt loodetud järeleandmisi / Andris Feldmanis

    Index Scriptorium Estoniae

    Feldmanis, Andris, 1982-

    2005-01-01

    Balti riigid ei olnud nõus loobuma kümnendikust eurotoetustest. Tallinnas viibinud Suurbritannia peaministri Tony Blairi väitel on EL-i uue finantsperspektiivi vastuvõtmine just uute liikmesriikide huvides. Vt. samas: Tiiu Laks. Riigijuhi visiit põhjustas Tallinnas vaid lühiajalisi liiklusseisakuid; Lisa: Blairi esinemine ei reetnud ebaedu; Kaivo Kopli. Uusliikmed andsid tuld juba enne ettepanekute saamist; Lisa: Toetus vanadelt liikmesmaadelt; Märt Kivine. EL-i eelarve: lahjem kui kunagi varem. Kommenteerib Taavi Veskimägi

  1. Performance of MIDAS Over East African Longitude Sector: Case Study During 4-14 March 2012 Quiet to Disturbed Geomagnetic Conditions

    Science.gov (United States)

    Giday, Nigussie M.; Katamzi-Joseph, Zama T.

    2018-02-01

    This study investigates the performance of a tomographic algorithm, Multi-Instrument and Data Analysis System (MIDAS), during an extended period of 4-14 March 2012, containing moderate and strong geomagnetic storms conditions, over an understudied and data scarce Eastern African longitude sector. Nonetheless, a relatively better distribution of Global Navigation Satellite Systems stations exists along a narrow longitude sector between 30°E and 44°E and latitude range of 30°S and 36°N that spans the equatorial, middle-, and low-latitude ionosphere. Then results are compared with independent global models such as International Reference Ionosphere 2012 (IRI-2012) and global ionosphere map (GIM). MIDAS performance was better than that of the IRI-2012 and GIM models in terms of capturing the diurnal trends as well as the short temporal total electron content (TEC) structures, with least root-mean-square errors (RMSEs). Overall, MIDAS results showed better agreement with the observation vertical TEC (VTEC) with computed maximum correlation coefficient (r) of 0.99 and minimum root-mean-square error (RMSE) of 2.91 TEC unit (1 TECU = 1,016 el m-2 over all the test stations and the validation days. Conversely, for the IRI-2012 and GIM TEC estimates, the corresponding maximum computed r values were 0.93 and 0.99, respectively, while the minimum RMSEs were 13.03 TECU and 6.52 TECU, respectively, for all the test stations and the validation days.

  2. CALIFICAREA JURIDICO-PENALĂ A VIOLENŢEI SEXUALE ASUPRA FEMEILOR CA FORMĂ DISTINCTĂ A VIOLENŢEI ÎN FAMILIE

    Directory of Open Access Journals (Sweden)

    Nicolae CORCEA

    2016-03-01

    Full Text Available Scopul acestui mesaj ştiinţific constă în rezolvarea controverselor doctrinare în domeniul calificării infracţiunii de violenţă în familie în una din formele ei speciale, cum ar fi violenţa sexuală. Cu toate că violenţa sexuală nu este prevă­zută expres de către legiuitor ca o formă distinctă a violenţei în familie, aceasta devine un fenomen extrem de răspândit. Autorul analizează violenţa împotriva femeilor bazată pe gen, arată caracterul discriminator al violenţei în familie îm­pot­riva femeilor în societăţile contemporane; examinează conceptul şi formele violenţei sexuale; demonstrează că violenţa sexuală în familie constituie o formă specială de subminare a femeilor şi a copiilor; propune calificarea juridico-penală a violenţei sexuale în familie.Qualification in criminal law of the sexual violence against women as a distinct form of the family violenceThe purpose of this scientific research consists in the solving of doctrinaire controversies in the sphere of legal appreciation of the criminal offence of family violence in one of its special forms as sexual violence. Even if sexual violence is not provided expressly in the penal legal norm as the independent form of family violence, this one became extremely spread. The author submits to a profound analysis the gender violence against women and demonstrates the discriminatory character of the family violence against women in the modern society; examines the concept and forms of sexual violence; proves that sexual violence in the family constitutes a special form of the women and children sup­pression; recommends legal appreciation of the criminal offence of the sexual violence in family. 

  3. Stable coordination of the inhibitory Ca2+ ion at MIDAS in integrin CD11b/CD18 by an antibody-derived ligand aspartate: Implications for integrin regulation and structure-based drug design

    Science.gov (United States)

    Mahalingam, Bhuvaneshwari; Ajroud, Kaouther; Alonso, Jose Luis; Anand, Saurabh; Adair, Brian; Horenstein, Alberto L; Malavasi, Fabio; Xiong, Jian-Ping; Arnaout, M. Amin

    2011-01-01

    A central feature of integrin interaction with physiologic ligands is the monodentate binding of a ligand carboxylate to a Mg2+ ion hexacoordinated at the metal-ion-dependent-adhesion site (MIDAS) in the integrin A-domain. This interaction stabilizes the A-domain in the high-affinity state, which is distinguished from the default low-affinity state by tertiary changes in the domain that culminate in cell adhesion. Small molecule ligand-mimetic integrin antagonists act as partial agonists, eliciting similar activating conformational changes in the A-domain, which has contributed to paradoxical adhesion and increased patient mortality in large clinical trials. As with other ligand-mimetic integrin antagonists, the function-blocking monoclonal antibody (mAb) 107 binds MIDAS of integrin CD11b/CD18 A-domain (CD11bA), but in contrast, it favors the inhibitory Ca2+ ion over Mg2+ at MIDAS. We determined the crystal structures of the Fab fragment of mAb 107 complexed to the low- and high-affinity states of CD11bA. Favored binding of Ca2+ at MIDAS is caused by the unusual symmetric bidentate ligation of a Fab-derived ligand Asp to a heptacoordinated MIDAS Ca2+. Binding of Fab 107 to CD11bA did not trigger the activating tertiary changes in the domain or in the full-length integrin. These data show that denticity of the ligand Asp/Glu can modify divalent cation selectivity at MIDAS and hence integrin function. Stabilizing the Ca2+ ion at MIDAS by bidentate ligation to a ligand Asp/Glu may provide one approach for designing pure integrin antagonists. PMID:22095715

  4. The role of rare morph advantage and conspicuousness in the stable gold-dark colour polymorphism of a crater lake Midas cichlid fish.

    Science.gov (United States)

    Torres-Dowdall, Julián; Golcher-Benavides, Jimena; Machado-Schiaffino, Gonzalo; Meyer, Axel

    2017-09-01

    Genetically based stable colour polymorphisms provide a unique opportunity to study the evolutionary processes that preserve genetic variability in the wild. Different mechanisms are proposed to promote the stability of polymorphisms, but only few empirical examples have been documented, resulting in an incomplete understanding of these mechanisms. A remarkable genetically determined stable colour polymorphism is found in the Nicaraguan Midas cichlid species complex (Amphilophus cf. citrinellus). All Midas cichlids start their life with a dark-grey coloration (dark morph), but individuals carrying the dominant "gold" allele (c. 10%) lose their melanophores later in life, revealing the underlying orange coloration (gold morph). How this polymorphism is maintained remains unclear. Two main hypotheses have been proposed, both suggesting differential predation upon colour morphs as the proximate mechanism. One predicts that the conspicuous gold morph is more likely to be preyed upon, but this disadvantage is balanced by their competitive dominance over the dark morph. The second hypothesis suggests a rare morph advantage where the rarer gold morph experiences less predation. Empirical evidence for either of these mechanisms is still circumstantial and inconclusive. We conducted two field experiments in a Nicaraguan crater lake using wax models simulating both morphs to determine predation pressure upon Midas cichlid colour morphs. First, we tested the interaction of coloration and depth on attack rate. Second, we tested the interaction of fish size and coloration. We contrasted the pattern of attacks from these experiments to the predicted predation patterns from the hypotheses proposed to explain the colour polymorphism's stability. Large models imitating colour morphs were attacked at similar rates irrespectively of their position in the water column. Yet, attacks upon small models resembling juveniles were directed mainly towards dark models. This resulted in a

  5. The Iterative Use of Single Case Research Designs to Advance the Science of EI/ECSE

    Science.gov (United States)

    Barton, Erin E.; Ledford, Jennifer R.; Lane, Justin D.; Decker, Jessica; Germansky, Sara E.; Hemmeter, Mary Louise; Kaiser, Ann

    2016-01-01

    Research in early intervention/early childhood special education (EI/ECSE) is focused on identifying effective practices related to positive outcomes for young children with disabilities and their families. Individual responses to evidence-based practices are often variable, and non-responders are common. Single case research (SCR) might be…

  6. Loeb või ei loe : IT on olulisem kui eales varem / James Champy

    Index Scriptorium Estoniae

    Champy, James

    2004-01-01

    Vastukajad ajakirja Think! 2003. aasta 2. numbris avaldatud Nicholas Carr'i artiklile "IT ei loe". Autori sõnul näitab kogemus, et infotehnoloogia (IT) on oluline, kui seda kasutatakse innovaatiliste lahenduste loomiseks ja ettevõtte konkurentsivõime muutmiseks

  7. HIV-positiivsed ei leia tihti tööd / Kadri Ibrus

    Index Scriptorium Estoniae

    Ibrus, Kadri

    2010-01-01

    Enamik Eesti HIV-positiivseid inimesi ei tööta. Eestit nõustanud USA eksperdi David Parkeri väitel tuleks HIV-positiivset aidata sotsiaalselt paremini hakkama saama, tegelema peaks korraga kõigi tema probleemidega

  8. Eesti koolid ei jaksa enam Microsoftilt tarkvara osta / Teele Tammeorg ; kommenteerinud Rain Laane

    Index Scriptorium Estoniae

    Tammeorg, Teele

    2013-01-01

    Eesti koolide arvutid on nii vananenud, et ei saa kasutada uuemaid operatsioonisüsteeme, Windowsi operatsioonisüsteem ja MS Office'i kasutamine aga kallineb vähemalt kümme korda. Arvamust avaldab ka Tallinna ülikooli haridustehnoloogia keskuse juht Mart Laanpere

  9. 7 CFR 650.20 - Reviewing and commenting on EIS's prepared by other agencies.

    Science.gov (United States)

    2010-01-01

    ... ensure the health and welfare of the agricultural community. Comments are to be based on knowledge...? What benefits are foregone if prime farmland is taken? (8) Impacts on ecosystems. Does the EIS describe impacts on major plant communities, and terrestrial and aquatic ecosystems? (9) Impacts on NRCS-assisted...

  10. Iraagi päästmiseks poliitikast ei piisa / Henry A. Kissinger

    Index Scriptorium Estoniae

    Kissinger, Henry, 1923-

    2007-01-01

    Endine USA riigisekretär arutleb Iraagi-poliitika üle. Autor nendib, et äkiline USA vägede väljaviimine Iraagist ei lõpetaks sõda, vaid muudaks ainult selle olusid, parim strateegia Iraagi kriisi ületamiseks on rahvusvahelise diplomaatia kasutamine. Lisa: USA väed Iraagis

  11. Rein Porro : ma ei kavatse lennuametist lahkuda / Rein Porro ; interv. Mirko Ojakivi

    Index Scriptorium Estoniae

    Porro, Rein, 1943-

    2006-01-01

    Lennuameti peadirektori asetäitja vastab küsimustele, kas ta rikkus lennundusseadust, väljastades lennuloa ettevõttele Pakker Avio, kas ta on läinud tülli lennuõnnetustega tuntuks saanud lennufirmaga ning seepärast püütakse temast vabaneda. Lisa: Uurimine rikkumisi ei tuvastanud

  12. Poliitikud ei leidnud staadioni planeeringule uusi lahendusi / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2008-01-01

    Riigikogu Pärnumaa saadikuteühenduse ja Pärnu linnavõimu esindajate ning spordiseltsi Kalev juhtide nõupidamine Kalevi staadioni ümberehituse käimalükkamiseks lõppes tulemusteta, sest kõiki osapooli rahuldava tulemuseni ei jõutud. Kommenteerivad Mark Soosaar ja Vello Järvesalu

  13. 75 FR 76444 - Environmental Impact Statement (EIS) for Construction and Operation of a Panoramic Survey...

    Science.gov (United States)

    2010-12-08

    ... potential environmental impacts associated with construction and operation of the proposed Panoramic Survey... DEPARTMENT OF DEFENSE Department of the Air Force Environmental Impact Statement (EIS) for Construction and Operation of a Panoramic Survey Telescope and Rapid Response System (Pan-STARRS) at the Summit...

  14. EMT ja Elioni katkestusi ei põhjustanud sama seade / Urmas Jaagant

    Index Scriptorium Estoniae

    Jaagant, Urmas

    2010-01-01

    EMT esindaja väitel ei olnud rikki läinud seade sama, mis tõi kaasa Elioni sidekatkestuse. 1. detsembril toimunud EMT sidekatkestuse põhjus selgub nädala lõpuks, katkestuse kompensatsiooniks on 3. detsembril EMT klientidele võrgusisesed kõned tasuta

  15. Eesti ei maksa Natura aladel toetust 7800 krooni hektari kohta / Ain Lember

    Index Scriptorium Estoniae

    Lember, Ain

    2004-01-01

    EL 2007-2013 eelarve eelnõu kohaselt võib Natura 2000 aladel tegutsevatele põllumajandustootjatele maksta põllumajanduskõlviku hektari kohta igal aastal kuni 7800 krooni. Põllumajandusministeeriumi spetsialistid ei pea nii suurte toetuste maksmist võimalikuks

  16. Naftahinna olulist langust lähiajal loota ei maksa / Erik Aru

    Index Scriptorium Estoniae

    Aru, Erik

    2008-01-01

    Analüütikute hinnangul kujuneb tänavu nafta keskmiseks hinnaks 83,87 krooni barrelilt. Energiaanalüütik Julian Lee on seisukohal, et keskpikas perspektiivis peaks naftapuhastustehaste mahu kasv sundima naftahinna langema, Deutsche Banki tooraineanalüüsi juhi Michael Lewise arvates ei saa praegu suuremat hinnalangust tulla. Lisa: OPEC viivitab toodangukärpega. Diagramm

  17. Ekspert : Eestis ei vajata linnugripi tõrjeks välisabi / Nataly Koppel

    Index Scriptorium Estoniae

    Koppel, Nataly

    2005-01-01

    Eesti veterinaar- ja toiduameti arvates saab Eesti haiguse tõkestamisel hakkama omal jõul, sest seadus lubab operatsioonidesse kaasata nii päästeametite töötajaid kui sõjaväelasi, mistõttu välisabi ei vajata. Lisa: Linnugripi tüvi H5N1

  18. 36 CFR 1010.8 - Actions that normally require an EIS.

    Science.gov (United States)

    2010-07-01

    ... impact on the environment, an EA is not required, and the Trust will prepare or direct the preparation of... or actions may significantly affect the environment and therefore require an EIS are described in 40...(b)(9); (2) Approval, funding, construction, and/or demolition in preparation for construction of any...

  19. 7 CFR 1955.136 - Environmental Assessment (EA) and Environmental Impact Statement (EIS).

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Environmental Assessment (EA) and Environmental Impact... Disposal of Inventory Property General § 1955.136 Environmental Assessment (EA) and Environmental Impact Statement (EIS). (a) Prior to a final decision on some disposal actions, an environmental assessment must be...

  20. Miks IMF ei kiirusta riike rahanduskriisist päästma? / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2008-01-01

    Mitu riiki taotleb IMF-ilt kriisiabi, IMF esitab neile abi andmiseks rangeid nõudeid. Varasemates kriisides on IMF-i rahast piisanud, kuid suuremaid tööstusriike ta välja aidata ei suudaks, selle juhi Dominique Strauss-Kahni prognoosi kohaselt peab IMF seekord välja andma sadu miljardeid dollareid. Lisa: Pangajuhti tabas seksiskandaal

  1. 75 FR 3746 - Ryan White HIV/AIDS Part C Early Intervention Services (EIS) Program

    Science.gov (United States)

    2010-01-22

    ... HIV/AIDS Part C Early Intervention Services (EIS) Program AGENCY: Health Resources and Services...: Critical funding for HIV/AIDS care and treatment to the target populations in Orange County, Orlando..., 2010). The Orange County Health Department is known Statewide as an exceptional site for HIV/AIDS care...

  2. Euroopa Liidus firmasid kahmav Gazprom teisi Venemaa turule ei lase / Krister Paris

    Index Scriptorium Estoniae

    Paris, Krister, 1977-

    2006-01-01

    EL tahab, et Venemaa ratifitseeriks energiaharta, mis võimaldaks Euroopa kompaniidel hakata ise Venemaa gaasi eksportima, Venemaa aga välismaist konkurentsi ei soovi. Samas on Gazprom huvitatud Suurbritannia suurima gaasivarustaja Centrica ostust ning tahab sisenenda ise gaasi tootva Hollandi turule. Lisa: Venemaa teine energiahoob: riiklik Rosneft. Vt. samas: Gaasitoodangu kasvatamine pole veel Gazpromi huvides

  3. Baltic Scandinavian Lines - Tallinki konkurent, kes end konkurendiks ei nimeta / Margo Heinla ; interv. Mart Riikoja

    Index Scriptorium Estoniae

    Heinla, Margo

    2005-01-01

    BSL-i tegevjuht kinnitab, et Tallink ei ole nende jaoks konkurent, kuna tegevusalad on nii erinevad. BSL-i ainus laev Via Mare on orienteeritud kaubavedudele Paldiskist Lõuna-Rootsi Västerviki ja Kapellskäri. Vaba ruumi korral veetakse üle ka sõiduautosid

  4. Aktinäitust 'Kalamees Hemingway' Pärnus ei näe / Grete Naaber

    Index Scriptorium Estoniae

    Naaber, Grete, 1942-

    1999-01-01

    Mark Soosaare poolt lubatud Hemingwayd kujutavat 20 maalist (autor hollandlane Peter Diem) ja 40 fotost (aastaist 1928-1936, autor Waldo Peirce) koosnevat aktinäitust 'Kalamees Hemingway' ei õnnestu Pärnusse tuua, kuna see läheks Uue kunsti muuseumile maksma 100 000 krooni.

  5. 78 FR 29124 - Draft Environmental Impact Statement (EIS) for the Implementation of Energy, Water, and Solid...

    Science.gov (United States)

    2013-05-17

    ... public comment period. Copies of the Draft EIS are available at the following libraries: Alamogordo Public Library, El Paso Main Library, Irving Schwartz Branch Library, New Mexico State University Zuhl Library, Richard Burges Branch Library, Thomas Branigan Memorial Library, and University of Texas at El...

  6. 77 FR 40144 - Adoption of the Environmental Impact Statement (EIS) and Participation in the Section 106...

    Science.gov (United States)

    2012-07-06

    ...) obligations related to MTA's request for financing for the East Side Access project through the FRA Railroad... Statement (EIS) and Participation in the Section 106 Programmatic Agreement for the East Side Access Project... adoption and recirculation of the Final Environmental Impact Statement for the East Side Access Project and...

  7. Pakistan vajab abi - kas maailma tõesti ei huvita? / Urmas Jaagant

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2010-01-01

    Pakistan saab igal aastal suurt rahvusvahelist abi. Mitmed riigid on üleujutustes Pakistani toetanud nüüdki kümnete miljonite dollaritega, kuid riikide tahe annetada on erinev, sest mitte iga abidollarit ei suunata Pakistanis sinna, kus seda tegelikult vajatakse

  8. 75 FR 51448 - Withdrawal of Notice for Preparation of an Environmental Impact Statement (EIS) for the Arkansas...

    Science.gov (United States)

    2010-08-20

    ... sustainable solutions for reducing head-cutting and scouring in the Ark-White Cutoff area. The two rivers are... Preparation of an Environmental Impact Statement (EIS) for the Arkansas White River Cutoff Study AGENCY... Impact Statement (EIS) for the Arkansas White River Cutoff Study. The original Notice of Intent (NOI) was...

  9. Multi-Criteria Decision Analysis Framework in the Selection of an Enterprise Integration (EI) Approach That Best Satisfies Organizational Requirements

    Science.gov (United States)

    Ngeru, James

    2012-01-01

    In the past few decades, adoption of Enterprise Integration (EI) through initiatives such as Service Oriented Architecture (SOA), Enterprise Application Integration (EAI) and Enterprise Resource Planning (ERP) has consistently dominated most of organizations' top strategic priorities. Additionally, the field of EI has generated a vast amount…

  10. 75 FR 16828 - Notice of Intent To Prepare and Scope an Environmental Impact Statement (EIS) for the Outer...

    Science.gov (United States)

    2010-04-02

    ... impacts to tourism and recreation activities, and ecological impacts from potential degradation of marine... Environmental Impact Statement (EIS) for the Outer Continental Shelf (OCS) Oil and Gas Leasing Program for 2012.... The EIS will analyze the potential impacts of the adoption of the proposed 5-year program. Background...

  11. 76 FR 21003 - Notice of Intent To Prepare a Programmatic Environmental Impact Statement (EIS) and Possible Land...

    Science.gov (United States)

    2011-04-14

    ... Prepare a Programmatic Environmental Impact Statement (EIS) and Possible Land Use Plan Amendments for... to prepare a Programmatic EIS for Allocation of Oil Shale and Tar Sands Resources on Lands... through local media, newsletters, and the project Web site at: http://blm.gov/st5c . The minutes and list...

  12. Moskvas hoitav Adolf Hitleri kolbatükk ei kuulu füürerile / Aadu Hiietamm

    Index Scriptorium Estoniae

    Hiietamm, Aadu, 1954-

    2009-01-01

    USA arheoloogi Nick Bellantoni avastus, et Moskvas hoitav Adolf Hitleri kuuliauguga koljutükk ei kuulugi füürerile, annab tõenäoliselt uut hoogu vandenõuteoreetikutele, kes usuvad, et Hitler ei teinud 1945. aastal enesetappu, vaid põgenes välismaale

  13. 78 FR 18325 - Intent To Prepare an Environmental Impact Statement (EIS) for the Formal Training Unit (FTU) and...

    Science.gov (United States)

    2013-03-26

    ... Statement (EIS) for the Formal Training Unit (FTU) and Main Operating Base 1 (MOB 1) for the Beddown of KC... Statement (EIS) for the Formal Training Unit (FTU) and Main Operating Base 1 (MOB 1) for the Beddown of KC...-46A tanker aircraft, associated infrastructure and manpower of the FTU and MOB 1 at existing active...

  14. The EIS beamline at the seeded free-electron laser FERMI

    Science.gov (United States)

    Simoncig, A.; Mincigrucci, R.; Principi, E.; Bencivenga, F.; Calvi, A.; Foglia, L.; Kurdi, G.; Raimondi, L.; Manfredda, M.; Mahne, N.; Gobessi, R.; Gerusina, S.; Fava, C.; Zangrando, M.; Matruglio, A.; Dal Zilio, S.; Masciotti, V.; Masciovecchio, C.

    2017-05-01

    Among the fourth-generation light sources, the Italian free-electron laser (FEL) FERMI is the only one operating in the high-gain harmonic generation (HGHG) seeding mode. FERMI delivers pulses characterized by a quasi transform limited temporal structure, photon energies lying in the extreme ultra-violet (EUV) region, supreme transversal and longitudinal coherences, high peak brilliance, and full control of the polarization. Such state of the art performances recently opened the doors to a new class of time-resolved spectroscopies, difficult or even impossible to be performed using self-amplified spontaneous sources (SASE) light sources. FERMI is currently equipped with three operating beamlines opened to external users (DiProI, LDM and EIS), while two more are under commissioning (MagneDYN and TeraFERMI). Here, we present the recent highlights of the EIS (Elastic and Inelastic Scattering) beamline, which has been purposely designed to take full advantage from the coherence, the intensity, the harmonics content, and the temporal duration of the pulses. EIS is a flexible experimental facility for time-resolved EUV scattering experiments on condensed matter systems, consisting of two independent end-stations. The first one (EIS-TIMEX) aims to study materials in metastable and warm dense matter (WDM) conditions, while the second end-station (EIS-TIMER) is fully oriented to the extension of four-wave mixing (FWM) spectroscopies towards the EUV spectral regions, trying to reveal the behavior of matter in portions of the mesoscopic regime of exchanged momentum impossible to be probed using conventional light sources.

  15. Robust Synchronization in an E/I Network with Medium Synaptic Delay and High Level of Heterogeneity

    International Nuclear Information System (INIS)

    Han Fang; Wang Zhi-Jie; Gong Tao; Fan Hong

    2015-01-01

    It is known that both excitatory and inhibitory neuronal networks can achieve robust synchronization only under certain conditions, such as long synaptic delay or low level of heterogeneity. In this work, robust synchronization can be found in an excitatory/inhibitory (E/I) neuronal network with medium synaptic delay and high level of heterogeneity, which often occurs in real neuronal networks. Two effects of post-synaptic potentials (PSP) to network synchronization are presented, and the synaptic contribution of excitatory and inhibitory neurons to robust synchronization in this E/I network is investigated. It is found that both excitatory and inhibitory neurons may contribute to robust synchronization in E/I networks, especially the excitatory PSP has a more positive effect on synchronization in E/I networks than that in excitatory networks. This may explain the strong robustness of synchronization in E/I neuronal networks. (paper)

  16. Species-specific differences in adaptive phenotypic plasticity in an ecologically relevant trophic trait: hypertrophic lips in Midas cichlid fishes.

    Science.gov (United States)

    Machado-Schiaffino, Gonzalo; Henning, Frederico; Meyer, Axel

    2014-07-01

    The spectacular species richness of cichlids and their diversity in morphology, coloration, and behavior have made them an ideal model for the study of speciation and adaptive evolution. Hypertrophic lips evolved repeatedly and independently in African and Neotropical cichlid radiations. Cichlids with hypertrophic lips forage predominantly in rocky crevices and it has been hypothesized that mechanical stress caused by friction could result in larger lips through phenotypic plasticity. To test the influence of the environment on the size and development of lips, we conducted a series of breeding and feeding experiments on Midas cichlids. Full-sibs of Amphilophus labiatus (thick-lipped) and Amphilophus citrinellus (thin-lipped) each were split into a control group which was fed food from the water column and a treatment group whose food was fixed to substrates. We found strong evidence for phenotypic plasticity on lip area in the thick-lipped species, but not in the thin-lipped species. Intermediate phenotypic values were observed in hybrids from thick- and thin-lipped species reared under "control" conditions. Thus, both a genetic, but also a phenotypic plastic component is involved in the development of hypertrophic lips in Neotropical cichlids. Moreover, species-specific adaptive phenotypic plasticity was found, suggesting that plasticity is selected for in recent thick-lipped species. © 2014 The Author(s). Evolution © 2014 The Society for the Study of Evolution.

  17. How to Meet the Last OIE Expert Surveillance Panel Recommendations on Equine Influenza (EI Vaccine Composition: A Review of the Process Required for the Recombinant Canarypox-Based EI Vaccine

    Directory of Open Access Journals (Sweden)

    Romain Paillot

    2016-11-01

    Full Text Available Vaccination is highly effective to prevent, control, and limit the impact of equine influenza (EI, a major respiratory disease of horses. However, EI vaccines should contain relevant equine influenza virus (EIV strains for optimal protection. The OIE expert surveillance panel annually reviews EIV evolution and, since 2010, the use of Florida clade 1 and 2 sub-lineages representative vaccine strains is recommended. This report summarises the development process of a fully- updated recombinant canarypox-based EI vaccine in order to meet the last OIE recommendations, including the vaccine mode of action, production steps and schedule. The EI vaccine ProteqFlu contains 2 recombinant canarypox viruses expressing the haemagglutinin of the A/equine/Ohio/03 and A/equine/Richmond/1/07 isolates (Florida clade 1 and 2 sub-lineages, respectively. The updated EI vaccine was tested for efficacy against the representative Florida clade 2 EIV strain A/equine/Richmond/1/07 in the Welsh mountain pony model. Protective antibody response, clinical signs of disease and virus shedding were compared with unvaccinated control ponies. Significant protection was measured in vaccinated ponies, which supports the vaccine registration. The recombinant canarypox-based EI vaccine was the first fully updated EI vaccine available in the EU, which will help to minimise the increasing risk of vaccine breakdown due to constant EIV evolution through antigenic drift.

  18. Extensive EIS characterization of commercially available lithium polymer battery cell for performance modelling

    DEFF Research Database (Denmark)

    Stanciu, Tiberiu; Stroe, Daniel Loan; Teodorescu, Remus

    2015-01-01

    or degradation of an electrochemical system. Used for Lithium-ion (Li-ion) batteries, this method allows for a fast and accurate assessment of the battery's impedance at any working point, without modifying the state of the battery. The influence of the operating conditions, state of charge (SOC) and temperature...... on the performance of a commercially available 53 Ah Lithium polymer battery cell, manufactured by Kokam Co. Ltd., is investigated in laboratory experiments, at its beginning of life, by means of EIS. A data fitting algorithm was used to obtain the parameter values for the proposed equivalent electrical circuit......, which was further selected for the development of an accurate EIS based performance model for the chosen Li-ion battery cell....

  19. Magnesium and its alloys as degradable biomaterials: corrosion studies using potentiodynamic and EIS electrochemical techniques

    Directory of Open Access Journals (Sweden)

    Wolf Dieter Müller

    2007-03-01

    Full Text Available Magnesium is potentially useful for orthopaedic and cardiovascular applications. However, the corrosion rate of this metal is so high that its degradation occurs before the end of the healing process. In industrial media the behaviour of several magnesium alloys have been probed to be better than magnesium performance. However, the information related to their corrosion behaviour in biological media is insufficient. The aim of this work is to study the influence of the components of organic fluids on the corrosion behaviour of Mg and AZ31 and LAE442 alloys using potentiodynamic, potentiostatic and EIS techniques. Results showed localized attack in chloride containing media. The breakdown potential decreased when chloride concentration increased. The potential range of the passivation region was extended in the presence of albumin. EIS measurements showed that the corrosion behaviour of the AZ31 was very different from that of LAE442 alloy in chloride solutions.

  20. Miks ma end ära ei tapa : [luuletused] / Paul-Eerik Rummo

    Index Scriptorium Estoniae

    Rummo, Paul-Eerik, 1942-

    2001-01-01

    Tekst eesti ja inglise k. P.-E. Rummo lühibiograafia eesti ja inglise k. lk. 131. Sisu: Miks ma end ära ei tapa = Why I don't kill myself ; "Maailm mu hinge ei tungind, vaid imbus..." = "The world did not invade my soul, it seeped into it..." ; "Taevas on kummargil üle maa..." = "The sky stoops over the earth..." ; "Nüüd anna jumal jaksu joosta juhuste sajus..." = "Now grant me God the strength to run through the rains of chance..." ; Jälle, jälle, jälle, jälle, jälle... = Again again again again again ; "maailm mille lõpp on mõeldav..." = "a world whose end is conceivable..." ; Kinni hoidmas = Clinging ; Poolüminal = Crooning

  1. Development and Electrochemical Investigations of an EIS- (Electrolyte-Insulator-Semiconductor based Biosensor for Cyanide Detection

    Directory of Open Access Journals (Sweden)

    Michael J. Schöning

    2007-08-01

    Full Text Available A cyanide biosensor based on a pH-sensitive p-doped electrolyte-insulator-semiconductor (EIS structure with an immobilised enzyme (cyanidase is realised at thelaboratory scale. The immobilisation of the cyanidase is performed in two distinct steps:first, the covalent coupling of cyanidase to an N-hydroxysuccinimide- (NHS activatedSepharoseTM gel and then, the physical entrapment of NHS-activated SepharoseTM with theimmobilised cyanidase in a dialysis membrane onto the EIS structure. The immobilisationof the cyanidase to the NHS-activated SepharoseTM is studied by means of gelelectrophoresis measurements and investigations using an ammonia- (NH3 selectiveelectrode. For the electrochemical characterisation of the cyanide biosensor,capacitance/voltage and constant capacitance measurements, respectively, have beencarried out. A differential measurement procedure is presented to evaluate the cyanideconcentration-dependent biosensor signals.

  2. Energy information systems (EIS): Technology costs, benefit, and best practice uses

    Energy Technology Data Exchange (ETDEWEB)

    Granderson, Jessica; Lin, Guanjing; Piette, Mary Ann

    2013-11-26

    Energy information systems are the web-based software, data acquisition hardware, and communication systems used to store, analyze, and display building energy data. They often include analysis methods such as baselining, benchmarking, load profiling, and energy anomaly detection. This report documents a large-scale assessment of energy information system (EIS) uses, costs, and energy benefits, based on a series of focused case study investigations that are synthesized into generalizable findings. The overall objective is to provide organizational decision makers with the information they need to make informed choices as to whether or not to invest in an EIS--a promising technology that can enable up to 20 percent site energy savings, quick payback, and persistent low-energy performance when implemented as part of best-practice energy management programs.

  3. 76 FR 21401 - Notice of Availability of the Draft EIS for the HB In-Situ Solution Mine Project, Eddy County, NM

    Science.gov (United States)

    2011-04-15

    ...] Notice of Availability of the Draft EIS for the HB In-Situ Solution Mine Project, Eddy County, NM AGENCY... prepared a Draft Environmental Impact Statement (EIS) for the HB In- Situ Solution Mine Project, and by... considered, the BLM must receive written comments on the HB In-Situ Solution Mine Project Draft EIS within 60...

  4. 77 FR 5566 - Notice of Availability of the Final EIS for the HB In-Situ Solution Mine Project, Eddy County...

    Science.gov (United States)

    2012-02-03

    ...] Notice of Availability of the Final EIS for the HB In-Situ Solution Mine Project, Eddy County, New Mexico... Statement (Final EIS) for the HB In-Situ Solution Mine Project, and by this notice is announcing its... the Federal Register. ADDRESSES: Copies of the HB In-Situ Solution Mining EIS are available for public...

  5. Ajude defitsiit : [kraadiõpe ei suuda katta isegi mitte prioriteetsete erialade vajadusi] / Jaan Laas

    Index Scriptorium Estoniae

    Laas, Jaan, 1938-

    2002-01-01

    Akadeemilise järelkasvu probleeme Eestis. Magistrite ja doktorite vähene koosseis ei vasta riigi majandusliku ja ühiskonna kultuurilise arengu vajadustele. 6.dets. 2001 Riigikogus heaks kiidetud dokumendis "Teadmistepõhine Eesti. Eesti teadus- ja arendustegevuse strateegia 2001-2006" prioriteedina märgitud erialad on kraadiõppega sama hästi kui katmata. Joon.: Teaduse finantseerimine 6 teadussuuna ja 59 teadusala lõikes a. 1998-2000

  6. PLASMA DIAGNOSTICS OF AN EIT WAVE OBSERVED BY HINODE/EIS AND SDO/AIA

    Energy Technology Data Exchange (ETDEWEB)

    Veronig, A. M.; Kienreich, I. W.; Muhr, N.; Temmer, M. [Institute of Physics, University of Graz, Universitaetsplatz 5, A-8010 Graz (Austria); Goemoery, P. [Astronomical Institute, Slovak Academy of Sciences, SK-05960 Tatranska Lomnica (Slovakia); Vrsnak, B. [Hvar Observatory, Faculty of Geodesy, Kaciceva 26, 1000 Zagreb (Croatia); Warren, H. P., E-mail: astrid.veronig@uni-graz.at [Space Science Division, Naval Research Laboratory, Washington, DC 20375 (United States)

    2011-12-10

    We present plasma diagnostics of an Extreme-Ultraviolet Imaging Telescope (EIT) wave observed with high cadence in Hinode/Extreme-Ultraviolet Imaging Spectrometer (EIS) sit-and-stare spectroscopy and Solar Dynamics Observatory/Atmospheric Imaging Assembly imagery obtained during the HOP-180 observing campaign on 2011 February 16. At the propagating EIT wave front, we observe downward plasma flows in the EIS Fe XII, Fe XIII, and Fe XVI spectral lines (log T Almost-Equal-To 6.1-6.4) with line-of-sight (LOS) velocities up to 20 km s{sup -1}. These redshifts are followed by blueshifts with upward velocities up to -5 km s{sup -1} indicating relaxation of the plasma behind the wave front. During the wave evolution, the downward velocity pulse steepens from a few km s{sup -1} up to 20 km s{sup -1} and subsequently decays, correlated with the relative changes of the line intensities. The expected increase of the plasma densities at the EIT wave front estimated from the observed intensity increase lies within the noise level of our density diagnostics from EIS Fe XIII 202/203 A line ratios. No significant LOS plasma motions are observed in the He II line, suggesting that the wave pulse was not strong enough to perturb the underlying chromosphere. This is consistent with the finding that no H{alpha} Moreton wave was associated with the event. The EIT wave propagating along the EIS slit reveals a strong deceleration of a Almost-Equal-To -540 m s{sup -2} and a start velocity of v{sub 0} Almost-Equal-To 590 km s{sup -1}. These findings are consistent with the passage of a coronal fast-mode MHD wave, pushing the plasma downward and compressing it at the coronal base.

  7. Põhjakeskuse tehingut ei saa tagasi pöörata / Anne Oja

    Index Scriptorium Estoniae

    Oja, Anne, 1970-

    2008-01-01

    Kobe Investmentsi partnerite Veljo Kuuse ja Kaire Kopli sõnul ei saa endine autoärimees Toomas Rüütmann Põhjakeskuse tehingut tagasi pöörata ning T. Rüütmann on keskuse projektist kätte saanud kordades enam raha, kui on sinna investeerinud. Vt. samas: Rüütmann väidab, et ta lasi varad arestida

  8. Andrzej Wajda : maailm küll teadis, aga ei hoolinud / Eda Post

    Index Scriptorium Estoniae

    Post, Eda, 1983-

    2008-01-01

    Poola filmi- ja teatrilavastaja Andrzej Wajda, kes pälvis sel aastal president Toomas Hendrik Ilveselt Maarjamaa Risti III klassi teenetemärgi. Tema viimasest mängufilmist "Katõn". Lisatud andmed elu ja töö kohta. Ordenit vastu võtma A. Wajda ei tule, sest 24. veebruaril 2008 läheb ta Los Angeleses Oscarite galale, kus tema film "Katõn" on parima võõrkeelse filmi auhinna nominent

  9. Tiigrihüppega ei paranda kingi ega osta leiba / Tarmo Mänd

    Index Scriptorium Estoniae

    Mänd, Tarmo, 1950-

    2007-01-01

    Ilmunud ka: Põhjarannik, 24. okt. 2007, lk. 2; Valgamaalane, 25. okt. 2007, lk. 2; Oma Saar, 25. okt. 2007, lk. 5; Vooremaa, 25. okt. 2007, lk. 2; Hiiu Leht, 26. okt. 2007, lk. 2; Harju Ekspress, 26. okt. 2007, lk. 6; Meie Maa, 27. okt. 2007, lk. 2; Koit, 30. okt. 2007, lk. 6. Riigikogus ei leidnud poolehoidu Rahvaliidu ettepanek suurendada uues eelarves valdadele mõeldud tulumaksu osa. Parlamendiliige loodab, et eelseisval eelarvekava menetlemisel riigikogus tõstatatakse see teema uuesti

  10. Kui ei maksa nüüd, maksad hiljem rohkem / Villu Zirnask

    Index Scriptorium Estoniae

    Zirnask, Villu, 1966-

    2008-01-01

    Autor toob kohe maksmise näitena Rootsi pankade päästmise 1990. aastate alguses ning hiljem maksmise näitena Jaapani, kus lasti hädas olevatel pankadel edasi toimetada. IMF-i analüütikute Luc Laeveni ja Fabian Valencia analüüsi põhjal on kohe maksmise variant üldiselt parem. Graafikud: Maailma finantskriisid 1970-2007. Lisa: Ei aastatki ilma kriisita

  11. ANALYSIS AND MODELING OF TWO FLARE LOOPS OBSERVED BY AIA AND EIS

    Energy Technology Data Exchange (ETDEWEB)

    Li, Y.; Ding, M. D. [School of Astronomy and Space Science, Nanjing University, Nanjing 210093 (China); Qiu, J. [Department of Physics, Montana State University, Bozeman, MT 59717 (United States)

    2012-10-10

    We analyze and model an M1.0 flare observed by SDO/AIA and Hinode/EIS to investigate how flare loops are heated and evolve subsequently. The flare is composed of two distinctive loop systems observed in extreme ultraviolet (EUV) images. The UV 1600 A emission at the feet of these loops exhibits a rapid rise, followed by enhanced emission in different EUV channels observed by the Atmospheric Imaging Assembly (AIA) and the EUV Imaging Spectrometer (EIS). Such behavior is indicative of impulsive energy deposit and the subsequent response in overlying coronal loops that evolve through different temperatures. Using the method we recently developed, we infer empirical heating functions from the rapid rise of the UV light curves for the two loop systems, respectively, treating them as two big loops with cross-sectional area of 5'' by 5'', and compute the plasma evolution in the loops using the EBTEL model. We compute the synthetic EUV light curves, which, with the limitation of the model, reasonably agree with observed light curves obtained in multiple AIA channels and EIS lines: they show the same evolution trend and their magnitudes are comparable by within a factor of two. Furthermore, we also compare the computed mean enthalpy flow velocity with the Doppler shift measurements by EIS during the decay phase of the two loops. Our results suggest that the two different loops with different heating functions as inferred from their footpoint UV emission, combined with their different lengths as measured from imaging observations, give rise to different coronal plasma evolution patterns captured both in the model and in observations.

  12. Üleilmse finantskriisi leevenemist silmapiiril veel ei paista / Erik Aru

    Index Scriptorium Estoniae

    Aru, Erik

    2007-01-01

    Maailma rahaturgudel kestab veel krediidikriis. Mitme vaatleja hinnangul näitab see, et kriis pole lahenenud ka pärast intressimäära langetamist, et tegemist on tõsise probleemiga. Investeerimispanga Goldman Sachs peaökonomist Jan Hatzius soovitab intressi veelgi vähendada. Hinnanguid kahjumi suuruse kohta. Lisad: Pangandus - pidev kriiside allikas; Euroopa keskpankureid inflatsioon ei loksuta

  13. Briti teadlane: kübersõda ei tule / Thomas Rid ; intervjueerinud Raimo Poom

    Index Scriptorium Estoniae

    Rid, Thomas

    2013-01-01

    Sõjauuringute õppejõud Thomas Rid leiab, et internetis on palju ohte, kuid kübersõda ei ole üks neist. Ridi arvates on äärmiselt ebatõenäoline, et NATO käivitaks kunagi küberrünnaku tõttu 5. artikli. Interneti kõige suuremaks ohustajaks pole NSA, vaid vabadust piirata soovivad autoritaarsed riigid

  14. Kui sõnadest enam ei piisa, siis - muusika / Kadri Mälk

    Index Scriptorium Estoniae

    Mälk, Kadri, 1958-

    2008-01-01

    Rahvusvahelisest ehtekunstisündmusest "Schmuckszene" (peakorraldaja Wolfgang Lösche) Münchenis, peanäitusest (kuraator Ralph Turner) Müncheni messikeskuses, satelliitnäitustest. Eestist pääses peanäitusele Maarja Niinemägi, peapreemia sai Jantje Fleischhut. Kaasaegse ehtekunsti toetajate ühenduse (Die Fördergesellschaft Neuer Schmuck) aastapreemia sai Peter Chang. Võrdluseks Tanel Veenre näitusest "Kui sõnadest ei piisa" Hop-galeriis

  15. Afgaane ei saa aidata vaid läbi soomuki akna / Toomas Sildam

    Index Scriptorium Estoniae

    Sildam, Toomas, 1961-

    2005-01-01

    Põhja-Afganistani Mazar-e-Sharifi linnas brittide juhtimisel tegutseva provintsi ülesehitusmeeskonna koosseisu kuulub kaks Eesti üksust - vaatlusmeeskond ja Eesti kaitseväe demineerijate rühm. Kaitseministeeriumi plaani kohaselt saadetakse 2006. aastal Lõuna-Afganistani ligi 120 Eesti sõdurit. Kaart. Vt. samas lühiintervjuud kapten Tiit Paljakuga: Kapten Tiit Paljak: me ei tee afgaanide eest kõike ära

  16. Comprehensive Summary and Analysis of Oral and Written Scoping Comments on the Hawaii Geothermal Project EIS (DOE Review Draft)

    Energy Technology Data Exchange (ETDEWEB)

    None

    1992-09-18

    This report contains summaries of the oral and written comments received during the scoping process for the Hawaii Geothermal Project (HGP) Environmental Impact Statement (EIS). Oral comments were presented during public scoping meetings; written comments were solicited at the public scoping meetings and in the ''Advance Notice of Intent'' and ''Notice of Intent'' (published in the ''Federal Register'') to prepare the HGP EIS. This comprehensive summary of scoping inputs provides an overview of the issues that have been suggested for inclusion in the HGP EIS.

  17. Genetic, comparative genomic, and expression analyses of the Mc1r locus in the polychromatic Midas cichlid fish (Teleostei, Cichlidae Amphilophus sp.) species group.

    Science.gov (United States)

    Henning, Frederico; Renz, Adina Josepha; Fukamachi, Shoji; Meyer, Axel

    2010-05-01

    Natural populations of the Midas cichlid species in several different crater lakes in Nicaragua exhibit a conspicuous color polymorphism. Most individuals are dark and the remaining have a gold coloration. The color morphs mate assortatively and sympatric population differentiation has been shown based on neutral molecular data. We investigated the color polymorphism using segregation analysis and a candidate gene approach. The segregation patterns observed in a mapping cross between a gold and a dark individual were consistent with a single dominant gene as a cause of the gold phenotype. This suggests that a simple genetic architecture underlies some of the speciation events in the Midas cichlids. We compared the expression levels of several candidate color genes Mc1r, Ednrb1, Slc45a2, and Tfap1a between the color morphs. Mc1r was found to be up regulated in the gold morph. Given its widespread association in color evolution and role on melanin synthesis, the Mc1r locus was further investigated using sequences derived from a genomic library. Comparative analysis revealed conserved synteny in relation to the majority of teleosts and highlighted several previously unidentified conserved non-coding elements (CNEs) in the upstream and downstream regions in the vicinity of Mc1r. The identification of the CNEs regions allowed the comparison of sequences from gold and dark specimens of natural populations. No polymorphisms were found between in the population sample and Mc1r showed no linkage to the gold phenotype in the mapping cross, demonstrating that it is not causally related to the color polymorphism in the Midas cichlid.

  18. Effluent information system (EIS)/onsite discharge information system (ODIS) 1985 executive summary

    International Nuclear Information System (INIS)

    Watanabe, T.

    1986-09-01

    The Effluent Information System (EIS) and Onsite Discharge Information System (ODIS) are Department of Energy (DOE) data base systems that aid DOE-Headquarters and Field Offices in managing the radioactive air and liquid effluents from DOE facilities. Data on effluents released offsite are entered into EIS and data on effluents discharged onsite and retained onsite are entered into ODIS. This document is a summary of information obtained from the CY 1985 effluent data received from all DOE and DOE contractor facilities and entered in the data bases. Data from previous years are also included. The summary consists of two parts. The first part summarizes information for effluents released offsite, and the second part summarizes information for effluents retained onsite. These summaries are taken from the routine annual reports sent to each DOE Operations Office. Special tabulations or specific data can be supplied upon request. Explanations of the significant changes are included in the EIS and ODIS graphic sections. Only those changes in activity greater than a factor of two and having a magnitude greater than 0.1 Ci are considered significant and are addressed in the explanation

  19. ASPECTE PRIVIND AUDITUL PERFORMANŢEI ÎN REPUBLICA MOLDOVA

    Directory of Open Access Journals (Sweden)

    Iulia CAPRIAN

    2015-12-01

    Full Text Available Auditul performanţei se concentrează pe determinarea faptului dacă activităţile, proiectele / programele / procesele se desfăşoară conform principiilor economicităţii, eficienţei şi eficacităţii şi dacă mai este loc pentru îmbunătăţiri. Acesta se realizează prin compararea performanţei în funcţie de setul de criterii prestabilite, precum şi prin analiza cauzelor ce determină apariţia problemelor sau devierilor de la aceste criterii, scopul principal fiind de a răspunde unor întrebări-cheie ale auditului şi de a furniza recomandări cu privire la îmbunătăţirile care se pot face.CERTAIN ASPECTS OF PERFORMANCE AUDIT IN THE REPUBLIC OF MOLDOVAPerformance auditing focuses on determining whether the activities, projects / programs / processes are conducted according to the principles of economy, efficiency and effectiveness and whether there is room for improvement; it is conducted by comparing performance on the basis of set criteria, as well as by analysis of the causes of the emergence of problems or deviations from these criteria, the main purpose being to answer certain key questions relevant for the audit and provide recommendations on improvements that can be made.

  20. Report of the investigation of the accident at the MIDAS MYTH/MILAGRO Trailer Park on Rainier Mesa at Nevada Test Site on February 15, 1984

    International Nuclear Information System (INIS)

    1984-01-01

    Fourteen persons were injured, one fatally, when the ground upon which they were working collapsed, forming a subsidence crater in the recording trailer park of the MIDAS MYTH/MILAGRO nuclear weapons effects test on Rainier Mesa at the US Department of Energy's Nevada Test Site on February 15, 1984. Those persons injured were contractor and laboratory employees from Reynolds Electrical and Engineering Co., Inc. (REECo), Pan American World Services, Inc. (PANAM), and the Los Alamos National Laboratory (LANL). This report presents the results of an investigation into the causes, effects, and response to the accident. 42 figures

  1. Calcified aquatic insect larval constructions in the Pleistocene tufa of Jebel El Mida, Gafsa, southern Tunisia: Recognition and paleoenvironmental significance

    Science.gov (United States)

    Ben Ahmed, Walid; Henchiri, Mohsen; Mastouri, Amna; Slim S'himi, Najet

    2018-04-01

    Calcified aquatic larval cases were recognized and identified in the Pleistocene tufa masses of Jebel El Mida, Gafsa, southern Tunisia. These larval constructions belong to three main insect families: caddisflies (Trichoptera, Hydropsychidae), midges (Diptera, Chironomidae) and aquatic moths (Lepidoptera, Pyralidae) that inhabited tubes in the tufa and spun nets. Each insect community has its distinctive characteristics of larval constructions that allow their recognition. The larval constructions recognized comprise fixed and portable (for caddisflies) dwelling cases and silken retreats and feeding capture nets. These last-mentioned are almost completely eroded and only remnants are preserved. The spatial distribution of these larval cases within the tufa is not random but, rather imposed by some specific paleohydraulic conditions. It's the reason why aquatic insect larval constructions are considered as prominent tool for the reconstruction of tufa and travertine depositional environments. Chironomid fixed dwelling cases (diameters range from 0.6 mm for clustered tubes to 3 mm) indicate the deposition of tufa under lotic (flowing) or lentic (standing) water conditions. The later hydraulic condition is shared with hydropsychids with fixed retreats (0.2-4 mm in diameter). Portable case-building caddisflies (case length ranging from 5 to 20 mm, and diameter from 3 to 5 mm at the cephalic end) prefer lentic conditions and are almost completely missing in high-energy flowing water locations that are preferred by pyralids (tubes are between 5 and 10 mm long and 3 mm in diameter). These insect families benefit from inhabiting the tufa by the availability of construction materials of their cases and the necessary space for their development.

  2. The View from the Trees: Nocturnal Bull Ants, Myrmecia midas, Use the Surrounding Panorama While Descending from Trees.

    Science.gov (United States)

    Freas, Cody A; Wystrach, Antione; Narendra, Ajay; Cheng, Ken

    2018-01-01

    Solitary foraging ants commonly use visual cues from their environment for navigation. Foragers are known to store visual scenes from the surrounding panorama for later guidance to known resources and to return successfully back to the nest. Several ant species travel not only on the ground, but also climb trees to locate resources. The navigational information that guides animals back home during their descent, while their body is perpendicular to the ground, is largely unknown. Here, we investigate in a nocturnal ant, Myrmecia midas , whether foragers travelling down a tree use visual information to return home. These ants establish nests at the base of a tree on which they forage and in addition, they also forage on nearby trees. We collected foragers and placed them on the trunk of the nest tree or a foraging tree in multiple compass directions. Regardless of the displacement location, upon release ants immediately moved to the side of the trunk facing the nest during their descent. When ants were released on non-foraging trees near the nest, displaced foragers again travelled around the tree to the side facing the nest. All the displaced foragers reached the correct side of the tree well before reaching the ground. However, when the terrestrial cues around the tree were blocked, foragers were unable to orient correctly, suggesting that the surrounding panorama is critical to successful orientation on the tree. Through analysis of panoramic pictures, we show that views acquired at the base of the foraging tree nest can provide reliable nest-ward orientation up to 1.75 m above the ground. We discuss, how animals descending from trees compare their current scene to a memorised scene and report on the similarities in visually guided behaviour while navigating on the ground and descending from trees.

  3. The View from the Trees: Nocturnal Bull Ants, Myrmecia midas, Use the Surrounding Panorama While Descending from Trees

    Directory of Open Access Journals (Sweden)

    Cody A. Freas

    2018-01-01

    Full Text Available Solitary foraging ants commonly use visual cues from their environment for navigation. Foragers are known to store visual scenes from the surrounding panorama for later guidance to known resources and to return successfully back to the nest. Several ant species travel not only on the ground, but also climb trees to locate resources. The navigational information that guides animals back home during their descent, while their body is perpendicular to the ground, is largely unknown. Here, we investigate in a nocturnal ant, Myrmecia midas, whether foragers travelling down a tree use visual information to return home. These ants establish nests at the base of a tree on which they forage and in addition, they also forage on nearby trees. We collected foragers and placed them on the trunk of the nest tree or a foraging tree in multiple compass directions. Regardless of the displacement location, upon release ants immediately moved to the side of the trunk facing the nest during their descent. When ants were released on non-foraging trees near the nest, displaced foragers again travelled around the tree to the side facing the nest. All the displaced foragers reached the correct side of the tree well before reaching the ground. However, when the terrestrial cues around the tree were blocked, foragers were unable to orient correctly, suggesting that the surrounding panorama is critical to successful orientation on the tree. Through analysis of panoramic pictures, we show that views acquired at the base of the foraging tree nest can provide reliable nest-ward orientation up to 1.75 m above the ground. We discuss, how animals descending from trees compare their current scene to a memorised scene and report on the similarities in visually guided behaviour while navigating on the ground and descending from trees.

  4. A combined SEM, CV and EIS study of multi-layered porous ceramic reactors for flue gas purification

    DEFF Research Database (Denmark)

    He, Zeming; Andersen, Kjeld Bøhm; Nygaard, Frederik Berg

    2013-01-01

    The effect of sintering temperature of 12-layered porous ceramic reactors (comprising 5 cells) was studied using scanning electron microscopy (SEM), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The difference in microstructures of the reactors was evaluated by SEM...

  5. Dive Data from Expedition Information System (EIS) for Islands in the Stream 2002 - Deep Reef Habitat - Office of Ocean Exploration

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Expeditions Information System (EIS) contains information recorded by the NOAA Office of Ocean Exploration's data manager during the 2002 "Islands in the Stream...

  6. Predicting risk of school refusal: Examining the incremental role of trait EI beyond personality and emotion regulation

    Directory of Open Access Journals (Sweden)

    Filippello Pina

    2018-01-01

    Full Text Available Research has not yet been deepened in the link between personality factors and risk of school refusal. Furthermore, previous studies fail to verify the direct relation between trait EI and the risk of school refusal. The present study examined personality traits, emotion regulation and trait EI for the contributory role they may play in predicting the risk of school refusal. The sample consisted of 311 participants, 112 males (36% and 199 females (64% with an average age of 14.19 (SD = .60, from a high school in the city of Messina (Sicily, Italy. Results show that the risk of school refusal is positively related to neuroticism and maladaptive emotion regulation strategies, while it is negatively related to the extroversion, agreeableness and conscientiousness and trait EI. Moreover, trait EI can be considered as a strong incremental negative predictor of risk of school refusal over and above personality traits and emotion regulation.

  7. 77 FR 39322 - Notice to Rescind the Notice of Intent to Prepare an Environmental Impact Statement (EIS...

    Science.gov (United States)

    2012-07-02

    ... to Prepare an Environmental Impact Statement (EIS), Kootenai County, ID AGENCY: Federal Highway... Federal Highway Administration (FHWA), in cooperation with Idaho Transportation Department (ITD... because congestion and safety concerns were rising within the project corridor and travel times for local...

  8. Arabidopsis thaliana Ei-5: Minor Vein Architecture Adjustment Compensates for Low Vein Density in Support of Photosynthesis.

    Science.gov (United States)

    Stewart, Jared J; Polutchko, Stephanie K; Demmig-Adams, Barbara; Adams, William W

    2018-01-01

    An Arabidopsis thaliana accession with naturally low vein density, Eifel-5 (Ei-5), was compared to Columbia-0 (Col-0) with respect to rosette growth, foliar vein architecture, photosynthesis, and transpiration. In addition to having to a lower vein density, Ei-5 grew more slowly, with significantly lower rates of rosette expansion, but had similar capacities for photosynthetic oxygen evolution on a leaf area basis compared to Col-0. The individual foliar minor veins were larger in Ei-5, with a greater number of vascular cells per vein, compared to Col-0. This compensation for low vein density resulted in similar values for the product of vein density × phloem cell number per minor vein in Ei-5 and Col-0, which suggests a similar capacity for foliar sugar export to support similar photosynthetic capacities per unit leaf area. In contrast, the product of vein density × xylem cell number per minor vein was significantly greater in Ei-5 compared to Col-0, and was associated not only with a higher ratio of water-transporting tracheary elements versus sugar-transporting sieve elements but also significantly higher foliar transpiration rates per leaf area in Ei-5. In contrast, previous studies in other systems had reported higher ratios of tracheary to sieve elements and higher transpiration rate to be associated with higher - rather than lower - vein densities. The Ei-5 accession thus further underscores the plasticity of the foliar vasculature by illustrating an example where a higher ratio of tracheary to sieve elements is associated with a lower vein density. Establishment of the Ei-5 accession, with a low vein density but an apparent overcapacity for water flux through the foliar xylem network, may have been facilitated by a higher level of precipitation in its habitat of origin compared to that of the Col-0 accession.

  9. Energy Return on Energy Invested (ERoEI) for photovoltaic solar systems in regions of moderate insolation

    International Nuclear Information System (INIS)

    Ferroni, Ferruccio; Hopkirk, Robert J.

    2016-01-01

    Many people believe renewable energy sources to be capable of substituting fossil or nuclear energy. However there exist very few scientifically sound studies, which apply due diligence to substantiating this impression. In the present paper, the case of photovoltaic power sources in regions of moderate insolation is analysed critically by using the concept of Energy Return on Energy Invested (ERoEI, also called EROI). But the methodology for calculating the ERoEI differs greatly from author-to-author. The main differences between solar PV Systems are between the current ERoEI and what is called the extended ERoEI (ERoEI EXT ). The current methodology recommended by the International Energy Agency is not strictly applicable for comparing photovoltaic (PV) power generation with other systems. The main reasons are due to the fact that on one hand, solar electricity is very material-intensive, labour-intensive and capital-intensive and on the other hand the solar radiation exhibits a rather low power density. - Highlights: •Data are available from several years of photovoltaic energy experience in northern Europe. •These are used to show the way to calculate a full, extended ERoEI. •The viability and sustainability in these latitudes of photovoltaic energy is questioned. •Use of photovoltaic technology is shown to result in creation of an energy sink.

  10. Acetylcholinesterase Inhibitors (AChEI's for the treatment of visual hallucinations in schizophrenia: A review of the literature

    Directory of Open Access Journals (Sweden)

    Patel Sachin S

    2010-09-01

    Full Text Available Abstract Background Visual hallucinations occur in various neurological diseases, but are most prominent in Lewy body dementia, Parkinson's disease and schizophrenia. The lifetime prevalence of visual hallucinations in patients with schizophrenia is much more common than conventionally thought and ranges from 24% to 72%. Cortical acetylcholine (ACh depletion has been associated with visual hallucinations; the level of depletion being related directly to the severity of the symptoms. Current understanding of neurobiological visual processing and research in diseases with reduced cholinergic function, suggests that AChEI's may prove beneficial in treating visual hallucinations. This offers the potential for targeted drug therapy of clinically symptomatic visual hallucinations in patients with schizophrenia using acetylcholinesterase inhibition. Methods A systematic review was carried out investigating the evidence for the effects of AChEI's in treating visual hallucinations in Schizophrenia. Results No evidence was found relating to the specific role of AChEI's in treating visual hallucinations in this patient group. Discussion Given the use of AChEI's in targeted, symptom specific treatment in other neuropsychiatric disorders, it is surprising to find no related literature in schizophrenia patients. The use of AChEI's in schizophrenia has investigated effects on cognition primarily with non cognitive effects measured more broadly. Conclusions We would suggest that more focused research into the effects of AChEI's on positive symptoms of schizophrenia, specifically visual hallucinations, is needed.

  11. MiDAS 2.0: an ecosystem-specific taxonomy and online database for the organisms of wastewater treatment systems expanded for anaerobic digester groups.

    Science.gov (United States)

    McIlroy, Simon Jon; Kirkegaard, Rasmus Hansen; McIlroy, Bianca; Nierychlo, Marta; Kristensen, Jannie Munk; Karst, Søren Michael; Albertsen, Mads; Nielsen, Per Halkjær

    2017-01-01

    Wastewater is increasingly viewed as a resource, with anaerobic digester technology being routinely implemented for biogas production. Characterising the microbial communities involved in wastewater treatment facilities and their anaerobic digesters is considered key to their optimal design and operation. Amplicon sequencing of the 16S rRNA gene allows high-throughput monitoring of these systems. The MiDAS field guide is a public resource providing amplicon sequencing protocols and an ecosystem-specific taxonomic database optimized for use with wastewater treatment facility samples. The curated taxonomy endeavours to provide a genus-level-classification for abundant phylotypes and the online field guide links this identity to published information regarding their ecology, function and distribution. This article describes the expansion of the database resources to cover the organisms of the anaerobic digester systems fed primary sludge and surplus activated sludge. The updated database includes descriptions of the abundant genus-level-taxa in influent wastewater, activated sludge and anaerobic digesters. Abundance information is also included to allow assessment of the role of emigration in the ecology of each phylotype. MiDAS is intended as a collaborative resource for the progression of research into the ecology of wastewater treatment, by providing a public repository for knowledge that is accessible to all interested in these biotechnologically important systems. http://www.midasfieldguide.org. © The Author(s) 2017. Published by Oxford University Press.

  12. Branching of the PIF3 regulatory network in Arabidopsis: roles of PIF3-regulated MIDAs in seedling development in the dark and in response to light.

    Science.gov (United States)

    Sentandreu, Maria; Leivar, Pablo; Martín, Guiomar; Monte, Elena

    2012-04-01

    Plants need to accurately adjust their development after germination in the underground darkness to ensure survival of the seedling, both in the dark and in the light upon reaching the soil surface. Recent studies have established that the photoreceptors phytochromes and the bHLH phytochrome interacting factors PIFs regulate seedling development to adjust it to the prevailing light environment during post-germinative growth. However, complete understanding of the downstream regulatory network implementing these developmental responses is still lacking. In a recent work, published in The Plant Cell, we report a subset of PIF3-regulated genes in dark-grown seedlings that we have named MIDAs (MISREGULATED IN DARK). Analysis of their functional relevance using mutants showed that four of them present phenotypic alterations in the dark, and that each affected a particular facet of seedling development, suggesting organ-specific branching in the signal that PIF3 relays downstream. Furthermore, our results also showed an altered response to light in seedlings with an impaired PIF3/MIDA regulatory network, indicating that these factors might also be essential to initiate and optimize the developmental adjustment of the seedling to the light environment.

  13. Global Alliance'i president: harige ennast, sest kogemusest tänapäeval ei piisa / Anne Gregory ; intervjueerinud Annela Laaneots

    Index Scriptorium Estoniae

    Gregory, Anne

    2013-01-01

    Intervjuu ajakirja Kaja mõttekojas esinenud maailma suhtekorralduse ja kommunikatsioonijuhtimise organisatsioonide ühenduse Global Alliance presidendi Anne Gregoryga, kes annab nõu, mida kommunikatsioonijuht peaks tegema, et olla organisatsioonis hinnatud ning enda eesmärkidest Global Alliance'i presidendina

  14. Heating and dynamics of two flare loop systems observed by AIA and EIS

    Energy Technology Data Exchange (ETDEWEB)

    Li, Y.; Ding, M. D. [School of Astronomy and Space Science, Nanjing University, Nanjing 210093 (China); Qiu, J., E-mail: yingli@nju.edu.cn [Department of Physics, Montana State University, Bozeman, MT 59717 (United States)

    2014-02-01

    We investigate heating and evolution of flare loops in a C4.7 two-ribbon flare on 2011 February 13. From Solar Dynamics Observatory/Atmospheric Imaging Assembly (AIA) imaging observations, we can identify two sets of loops. Hinode/EUV Imaging Spectrometer (EIS) spectroscopic observations reveal blueshifts at the feet of both sets of loops. The evolution and dynamics of the two sets are quite different. The first set of loops exhibits blueshifts for about 25 minutes followed by redshifts, while the second set shows stronger blueshifts, which are maintained for about one hour. The UV 1600 observation by AIA also shows that the feet of the second set of loops brighten twice. These suggest that continuous heating may be present in the second set of loops. We use spatially resolved UV light curves to infer heating rates in the few tens of individual loops comprising the two loop systems. With these heating rates, we then compute plasma evolution in these loops with the 'enthalpy-based thermal evolution of loops' model. The results show that, for the first set of loops, the synthetic EUV light curves from the model compare favorably with the observed light curves in six AIA channels and eight EIS spectral lines, and the computed mean enthalpy flow velocities also agree with the Doppler shift measurements by EIS. For the second set of loops modeled with twice-heating, there are some discrepancies between modeled and observed EUV light curves in low-temperature bands, and the model does not fully produce the prolonged blueshift signatures as observed. We discuss possible causes for the discrepancies.

  15. Dereplication of pentacyclic triterpenoids in plants by GC-EI/MS.

    Science.gov (United States)

    Gu, Jian-Qiao; Wang, Yuehong; Franzblau, Scott G; Montenegro, Gloria; Timmermann, Barbara N

    2006-01-01

    Three common plant-derived pentacyclic triterpenoids, oleanolic acid (1), betulinic acid (2) and ursolic acid (3), have been found to exhibit moderate anti-tubercular activity in a microplate alamar blue assay. In order to facilitate the discovery of novel anti-tubercular leads with diverse chemical structures, a new and rapid GC-EI/MS method was developed simultaneously and unambiguously to dereplicate 1-3 as their methyl esters with limits of detection of 25.6, 26.9 and 26.8 ng, respectively.

  16. Effluent Information System (EIS) / Onsite Discharge Information System (ODIS): 1986 executive summary

    International Nuclear Information System (INIS)

    Watanabe, T.

    1987-09-01

    Department of Energy (DOE) data base systems aid DOE-Headquarters and Field Offices in managing the radioactive air and liquid effluents from DOE facilities. Data on effluents released offsite are entered into effluent information system (EIS) and data on effluents discharged onsite and retained onsite are entered into Onsite Discharge Information System (ODIS). This document is a summary of information obtained from the CY 1986 effluent data received from all DOE and DOE contractor facilities and entered in the data bases. Data from previous years are also included. The summary consists of information for effluents released offsite, and information for effluents retained onsite

  17. Corrosion Protection Performance of Polyester-Melamine Coating with Natural Wood Fiber Using EIS Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Shin, PyongHwa; Shon, MinYoung [Pukyong National University, Busan (Korea, Republic of); Jo, DuHwan [POSCO, Gwangyang (Korea, Republic of)

    2016-04-15

    In the present study, polyester-melamine coating systems with natural wood fiber (NWF) were prepared and the effects of NWF on the corrosion protectiveness of the polyester-melamine coating were examined using EIS analysis. From the results, higher average surface roughness was observed with increase of NWF content. Water diffusivity and water uptake into the polyester-melamine coatings with NWF were much higher than that into the pure polyester-melamine coating. The decrease in the impedance modulus |Z| was associated with the localized corrosion on carbon steel, confirming that corrosion protection of the polyester-melamine coatings with NWF well agrees with its water transport behavior.

  18. Õiguste kaitse ei tohi sõltuda rahakoti paksusest / Ken-Marti Vaher

    Index Scriptorium Estoniae

    Vaher, Ken-Marti, 1974-

    2005-01-01

    Riigi õigusabi seadusest, mis rakendub 1. märtsist 2005. Sama ka Pärnu Postimees 1. märts 2005, lk. 15 ; Võrumaa Teataja 1. märts 2005, lk. 2 ; Koit 1. märts 2005, lk. 6 ; Põhjarannik 1. märts 2005, lk. 2 ; Vali Uudised 4. märts 2005, lk. 2 ; Vooremaa 5. märts 2005, lk. 2 ; Meie Maa 10. märts 2005, lk. 2 ; Järva Teataja 5. märts 2005, lk. 2 artiklis pealkiri kujul: õiguste kaitse ei sõltu rahakotist ; Videvik 10. märts 2005, lk. 5

  19. The Application of EIS and PIV Methods to the Measurement of Aerated Flow

    Directory of Open Access Journals (Sweden)

    Fejfarová M.

    2013-04-01

    Full Text Available The paper describes measurements in the aerated water medium using modern methods PIV (Particle Image Velocimetry and EIS (Electrical Impedance Spectrometry, which are applied in the Laboratory of Water Management Research (LVV of the Department of Water Structures (UVST at the Faculty of Civil Engineering (FAST of Brno University of Technology (VUT. Measurements of the water medium were carried out for three different aeration intensities at special experimental workplaces. The experiment was focused on the capability of the methods to monitor the air content in the water.

  20. Enhanced gravity-wave activity and interhemispheric coupling during the MaCWAVE/MIDAS northern summer program 2002

    Directory of Open Access Journals (Sweden)

    E. Becker

    2006-07-01

    Full Text Available We present new sensitivity experiments that link observed anomalies of the mesosphere and lower thermosphere at high latitudes during the MaCWAVE/MIDAS summer program 2002 to enhanced planetary Rossby-wave activity in the austral winter troposphere.

    We employ the same general concept of a GCM having simplified representations of radiative and latent heating as in a previous study by Becker et al. (2004. In the present version, however, the model includes no gravity wave (GW parameterization. Instead we employ a high vertical and a moderate horizontal resolution in order to describe GW effects explicitly. This is supported by advanced, nonlinear momentum diffusion schemes that allow for a self-consistent generation of inertia and mid-frequency GWs in the lower atmosphere, their vertical propagation into the mesosphere and lower thermosphere, and their subsequent dissipation which is induced by prescribed horizontal and vertical mixing lengths as functions of height.

    The main anomalies in northern summer 2002 consist of higher temperatures than usual above 82 km, an anomalous eastward mean zonal wind between 70 and 90 km, an altered meridional flow, enhanced turbulent dissipation below 80 km, and enhanced temperature variations associated with GWs. These signals are all reasonably described by differences between two long-integration perpetual model runs, one with normal July conditions, and another run with modified latent heating in the tropics and Southern Hemisphere to mimic conditions that correspond to the unusual austral winter 2002. The model response to the enhanced winter hemisphere Rossby-wave activity has resulted in both an interhemispheric coupling through a downward shift of the GW-driven branch of the residual circulation and an increased GW activity at high summer latitudes. Thus a quantitative explanation of the dynamical state of the northern mesosphere and lower

  1. Sampling genetic diversity in the sympatrically and allopatrically speciating Midas cichlid species complex over a 16 year time series

    Directory of Open Access Journals (Sweden)

    Bunje Paul ME

    2007-02-01

    Full Text Available Abstract Background Speciation often occurs in complex or uncertain temporal and spatial contexts. Processes such as reinforcement, allopatric divergence, and assortative mating can proceed at different rates and with different strengths as populations diverge. The Central American Midas cichlid fish species complex is an important case study for understanding the processes of speciation. Previous analyses have demonstrated that allopatric processes led to species formation among the lakes of Nicaragua as well as sympatric speciation that is occurring within at least one crater lake. However, since speciation is an ongoing process and sampling genetic diversity of such lineages can be biased by collection scheme or random factors, it is important to evaluate the robustness of conclusions drawn on individual time samples. Results In order to assess the validity and reliability of inferences based on different genetic samples, we have analyzed fish from several lakes in Nicaragua sampled at three different times over 16 years. In addition, this time series allows us to analyze the population genetic changes that have occurred between lakes, where allopatric speciation has operated, as well as between different species within lakes, some of which have originated by sympatric speciation. Focusing on commonly used genetic markers, we have analyzed both DNA sequences from the complete mitochondrial control region as well as nuclear DNA variation at ten microsatellite loci from these populations, sampled thrice in a 16 year time period, to develop a robust estimate of the population genetic history of these diversifying lineages. Conclusion The conclusions from previous work are well supported by our comprehensive analysis. In particular, we find that the genetic diversity of derived crater lake populations is lower than that of the source population regardless of when and how each population was sampled. Furthermore, changes in various estimates of

  2. Structure-guided design of a high-affinity platelet integrin αIIbβ3 receptor antagonist that disrupts Mg²⁺ binding to the MIDAS.

    Science.gov (United States)

    Zhu, Jieqing; Choi, Won-Seok; McCoy, Joshua G; Negri, Ana; Zhu, Jianghai; Naini, Sarasija; Li, Jihong; Shen, Min; Huang, Wenwei; Bougie, Daniel; Rasmussen, Mark; Aster, Richard; Thomas, Craig J; Filizola, Marta; Springer, Timothy A; Coller, Barry S

    2012-03-14

    An integrin found on platelets, α(IIb)β(3) mediates platelet aggregation, and α(IIb)β(3) antagonists are effective antithrombotic agents in the clinic. Ligands bind to integrins in part by coordinating a magnesium ion (Mg(2+)) located in the β subunit metal ion-dependent adhesion site (MIDAS). Drugs patterned on the integrin ligand sequence Arg-Gly-Asp have a basic moiety that binds the α(IIb) subunit and a carboxyl group that coordinates the MIDAS Mg(2+) in the β(3) subunits. They induce conformational changes in the β(3) subunit that may have negative consequences such as exposing previously hidden epitopes and inducing the active conformation of the receptor. We recently reported an inhibitor of α(IIb)β(3) (RUC-1) that binds exclusively to the α(IIb) subunit; here, we report the structure-based design and synthesis of RUC-2, a RUC-1 derivative with a ~100-fold higher affinity. RUC-2 does not induce major conformational changes in β(3) as judged by monoclonal antibody binding, light scattering, gel chromatography, electron microscopy, and a receptor priming assay. X-ray crystallography of the RUC-2-α(IIb)β(3) headpiece complex in 1 mM calcium ion (Ca(2+))/5 mM Mg(2+) at 2.6 Å revealed that RUC-2 binds to α(IIb) the way RUC-1 does, but in addition, it binds to the β(3) MIDAS residue glutamic acid 220, thus displacing Mg(2+) from the MIDAS. When the Mg(2+) concentration was increased to 20 mM, however, Mg(2+) was identified in the MIDAS and RUC-2 was absent. RUC-2's ability to inhibit ligand binding and platelet aggregation was diminished by increasing the Mg(2+) concentration. Thus, RUC-2 inhibits ligand binding by a mechanism different from that of all other α(IIb)β(3) antagonists and may offer advantages as a therapeutic agent.

  3. EIS study on corrosion and scale processes and their inhibition in cooling system media

    Energy Technology Data Exchange (ETDEWEB)

    Marin-Cruz, J. [Universidad Autonoma Metropolitana, Departamento de Quimica, Apdo. Postal 55-534, 09340 Mexico, DF (Mexico) and Instituto Mexicano del Petroleo, Coordinacion de Ingenieria Molecular, Competencia de Quimica Aplicada, Eje Central Lazaro Cardenas No. 152, CP 07730, DF (Mexico)]. E-mail: jmarin@imp.mx; Cabrera-Sierra, R. [Universidad Autonoma Metropolitana, Departamento de Quimica, Apdo. Postal 55-534, 09340 Mexico, DF (Mexico); Escuela Superior de Ingenieria Quimica e Industrias Extractivas (ESIQIE-IPN), Departamento de Metalurgia, UPALM Zacatenco AP 75-874, CP 07338, DF (Mexico); Pech-Canul, M.A. [Departamento de Fisica Aplicada, Centro de Investigacion y de Estudios, Avanzados del IPN, AP 73 Cordemex, CP 97310, Merida, Yucatan (Mexico); Gonzalez, I. [Universidad Autonoma Metropolitana, Departamento de Quimica, Apdo. Postal 55-534, 09340 Mexico, DF (Mexico)]. E-mail: igm@xanum.uam.mx

    2006-01-20

    A study of the carbon steel/cooling water interface was carried out using electrochemical impedance spectroscopy (EIS). EIS spectra reveal that a layer of corrosion and scale products forms naturally and evolves with the immersion time modifying the carbon steel/cooling water interface and giving rise to corrosion and scale processes. In addition, the nature of the layer formed on the metal was found to depend on the inhibitor used. It was established that the corrosion inhibitor (hydroxyphosphonoacetic acid (HPA)) chelates with Ca(II) ion generating a layer with resistive properties that provides good protection against corrosion. In contrast, the scale inhibitor (1-hydroxy-ethane-1,1-diphosphonic acid (HEDP)) is incorporated into the calcium carbonate crystals at the surface, modifying the structure and diminishing scale formation in the surface; this additive additionally inhibited corrosion. These observations were supported by scanning electronic microscopy (SEM) and corroborate previous studies performed by other techniques on HPA and HEDP. Finally, a synergistic effect was observed between these inhibitors that provides good protection to steel against corrosion and scaling in cooling media.

  4. Evaluation of the corrosion resistance of anodized aluminum 6061 using electrochemical impedance spectroscopy (EIS)

    Energy Technology Data Exchange (ETDEWEB)

    Huang Yuelong [Corrosion and Environmental Effects Laboratory (CEEL), Mork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, CA 90089-0241 (United States); Shih Hong [Lam Research Corporation, 4400 Cushing Parkway, Fremont, CA 94538 (United States)], E-mail: hong.shih@lamrc.com; Huang, Huochuan; Daugherty, John; Wu Shun; Ramanathan, Sivakami; Chang, Chris [Lam Research Corporation, 4400 Cushing Parkway, Fremont, CA 94538 (United States); Mansfeld, Florian [Corrosion and Environmental Effects Laboratory (CEEL), Mork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, CA 90089-0241 (United States)], E-mail: mansfeld@usc.edu

    2008-12-15

    The corrosion resistance of anodized Al 6061 produced by two different anodizing and sealing processes was evaluated using electrochemical impedance spectroscopy (EIS). The scanning electron microscope (SEM) was employed to determine the surface structure and the thickness of the anodized layers. The EIS data revealed that there was very little change of the properties of the anodized layers for samples that were hard anodized in a mixed acid solution and sealed in hot water over a 365 day exposure period in a 3.5 wt% NaCl solution. The specific admittance A{sub s} and the breakpoint frequency f{sub b} remained constant with exposure time confirming that the hard anodizing process used in this study was very effective in providing excellent corrosion resistance of anodized Al 6061 over extended exposure periods. Some minor degradation of the protective properties of the anodized layers was observed for samples that were hard anodized in H{sub 2}SO{sub 4} and exposed to the NaCl solution for 14 days.

  5. EIS study on corrosion and scale processes and their inhibition in cooling system media

    International Nuclear Information System (INIS)

    Marin-Cruz, J.; Cabrera-Sierra, R.; Pech-Canul, M.A.; Gonzalez, I.

    2006-01-01

    A study of the carbon steel/cooling water interface was carried out using electrochemical impedance spectroscopy (EIS). EIS spectra reveal that a layer of corrosion and scale products forms naturally and evolves with the immersion time modifying the carbon steel/cooling water interface and giving rise to corrosion and scale processes. In addition, the nature of the layer formed on the metal was found to depend on the inhibitor used. It was established that the corrosion inhibitor (hydroxyphosphonoacetic acid (HPA)) chelates with Ca(II) ion generating a layer with resistive properties that provides good protection against corrosion. In contrast, the scale inhibitor (1-hydroxy-ethane-1,1-diphosphonic acid (HEDP)) is incorporated into the calcium carbonate crystals at the surface, modifying the structure and diminishing scale formation in the surface; this additive additionally inhibited corrosion. These observations were supported by scanning electronic microscopy (SEM) and corroborate previous studies performed by other techniques on HPA and HEDP. Finally, a synergistic effect was observed between these inhibitors that provides good protection to steel against corrosion and scaling in cooling media

  6. E-I balance emerges naturally from continuous Hebbian learning in autonomous neural networks.

    Science.gov (United States)

    Trapp, Philip; Echeveste, Rodrigo; Gros, Claudius

    2018-06-12

    Spontaneous brain activity is characterized in part by a balanced asynchronous chaotic state. Cortical recordings show that excitatory (E) and inhibitory (I) drivings in the E-I balanced state are substantially larger than the overall input. We show that such a state arises naturally in fully adapting networks which are deterministic, autonomously active and not subject to stochastic external or internal drivings. Temporary imbalances between excitatory and inhibitory inputs lead to large but short-lived activity bursts that stabilize irregular dynamics. We simulate autonomous networks of rate-encoding neurons for which all synaptic weights are plastic and subject to a Hebbian plasticity rule, the flux rule, that can be derived from the stationarity principle of statistical learning. Moreover, the average firing rate is regulated individually via a standard homeostatic adaption of the bias of each neuron's input-output non-linear function. Additionally, networks with and without short-term plasticity are considered. E-I balance may arise only when the mean excitatory and inhibitory weights are themselves balanced, modulo the overall activity level. We show that synaptic weight balance, which has been considered hitherto as given, naturally arises in autonomous neural networks when the here considered self-limiting Hebbian synaptic plasticity rule is continuously active.

  7. Facts and artefacts regarding correlation between skin electrical impedance spectroscopy (EIS) and blood glucose

    International Nuclear Information System (INIS)

    Ollmar, Stig; Nicander, Ingrid; Åberg, Peter; Bolinder, Jan

    2013-01-01

    Earlier observations on possible co-variation between skin EIS and blood glucose prompted us to map and include other factors at play in the predictive model. Skin pH would be one such factor. A cohort of 20 diabetics was investigated, taking around 30 measurements spread over each of two different days 2–21 days apart. Each measurement comprises skin EIT in the frequency range 1kHz to 2.5MHz, skin pH, and immediately evaluated blood samples. There is a co-variation for some, but not all, test persons. The relationship gets stronger on the group level by adding pH-information, but is still poor or non-existent for some test persons. Non-invasive EIS measurements on skin is influenced by skin hydration, blood glucose, skin pH, body location, season, environmental factors, and variables not yet understood. Since impedance related parameters are used to estimate skin hydration, users of such devices should be aware that skin pH may influence as much as the water content of the stratum corneum.

  8. Evaluation of the corrosion resistance of anodized aluminum 6061 using electrochemical impedance spectroscopy (EIS)

    International Nuclear Information System (INIS)

    Huang Yuelong; Shih Hong; Huang, Huochuan; Daugherty, John; Wu Shun; Ramanathan, Sivakami; Chang, Chris; Mansfeld, Florian

    2008-01-01

    The corrosion resistance of anodized Al 6061 produced by two different anodizing and sealing processes was evaluated using electrochemical impedance spectroscopy (EIS). The scanning electron microscope (SEM) was employed to determine the surface structure and the thickness of the anodized layers. The EIS data revealed that there was very little change of the properties of the anodized layers for samples that were hard anodized in a mixed acid solution and sealed in hot water over a 365 day exposure period in a 3.5 wt% NaCl solution. The specific admittance A s and the breakpoint frequency f b remained constant with exposure time confirming that the hard anodizing process used in this study was very effective in providing excellent corrosion resistance of anodized Al 6061 over extended exposure periods. Some minor degradation of the protective properties of the anodized layers was observed for samples that were hard anodized in H 2 SO 4 and exposed to the NaCl solution for 14 days

  9. Fuzzy logic modeling of EIS measurements on lithium-ion batteries

    International Nuclear Information System (INIS)

    Singh, Pritpal; Vinjamuri, Ramana; Wang, Xiquan; Reisner, David

    2006-01-01

    A fuzzy logic-based state of health (SOH) meter is being developed for lithium-ion (Li-ion) batteries for potential use in portable defibrillators. Electrochemical impedance spectroscopy (EIS) measurements have been made from which input parameters for a fuzzy logic model to estimate the state of charge (SOC) and SOH are derived. The batteries are discharged continuously at a 1.4 A load current to simulate the constant current draw during the monitoring and recording of a patient's EKG, and periodically interrupted by 10 A pulses to simulate the battery discharge to charge up the capacitor that is in turn discharged to supply high voltage to the electrodes for the defibrillation of the patient. The test procedures included both voltage recovery and EIS measurements, and were made as the batteries were being discharged and over 30 charge/discharge cycles. Accurate models have been developed to estimate the number of pulses that the battery pack can deliver at various stages of its cycle life (SOC measure) and the number of charge/discharge cycles (SOH measure) that it had undergone

  10. Facts and artefacts regarding correlation between skin electrical impedance spectroscopy (EIS) and blood glucose

    Science.gov (United States)

    Ollmar, Stig; Nicander, Ingrid; Åberg, Peter; Bolinder, Jan

    2013-04-01

    Earlier observations on possible co-variation between skin EIS and blood glucose prompted us to map and include other factors at play in the predictive model. Skin pH would be one such factor. A cohort of 20 diabetics was investigated, taking around 30 measurements spread over each of two different days 2-21 days apart. Each measurement comprises skin EIT in the frequency range 1kHz to 2.5MHz, skin pH, and immediately evaluated blood samples. There is a co-variation for some, but not all, test persons. The relationship gets stronger on the group level by adding pH-information, but is still poor or non-existent for some test persons. Non-invasive EIS measurements on skin is influenced by skin hydration, blood glucose, skin pH, body location, season, environmental factors, and variables not yet understood. Since impedance related parameters are used to estimate skin hydration, users of such devices should be aware that skin pH may influence as much as the water content of the stratum corneum.

  11. Susceptibility of the wild-derived inbred CAST/Ei mouse to infection by orthopoxviruses analyzed by live bioluminescence imaging

    International Nuclear Information System (INIS)

    Americo, Jeffrey L.; Sood, Cindy L.; Cotter, Catherine A.; Vogel, Jodi L.; Kristie, Thomas M.; Moss, Bernard; Earl, Patricia L.

    2014-01-01

    Classical inbred mice are extensively used for virus research. However, we recently found that some wild-derived inbred mouse strains are more susceptible than classical strains to monkeypox virus. Experiments described here indicated that the 50% lethal dose of vaccinia virus (VACV) and cowpox virus (CPXV) were two logs lower in wild-derived inbred CAST/Ei mice than classical inbred BALB/c mice, whereas there was little difference in the susceptibility of the mouse strains to herpes simplex virus. Live bioluminescence imaging was used to follow spread of pathogenic and attenuated VACV strains and CPXV virus from nasal passages to organs in the chest and abdomen of CAST/Ei mice. Luminescence increased first in the head and then simultaneously in the chest and abdomen in a dose-dependent manner. The spreading kinetics was more rapid with VACV than CPXV although the peak photon flux was similar. These data suggest advantages of CAST/Ei mice for orthopoxvirus studies. - Highlights: • Wild-derived inbred CAST/Ei mice are susceptible to vaccinia virus and cowpox virus. • Morbidity and mortality from orthopoxviruses are greater in CAST/Ei than BALB/c mice. • Morbidity and mortality from herpes simplex virus type 1 are similar in both mice. • Imaging shows virus spread from nose to lungs, abdominal organs and brain. • Vaccinia virus spreads more rapidly than cowpox virus

  12. Susceptibility of the wild-derived inbred CAST/Ei mouse to infection by orthopoxviruses analyzed by live bioluminescence imaging

    Energy Technology Data Exchange (ETDEWEB)

    Americo, Jeffrey L.; Sood, Cindy L.; Cotter, Catherine A.; Vogel, Jodi L.; Kristie, Thomas M.; Moss, Bernard, E-mail: bmoss@nih.gov; Earl, Patricia L., E-mail: pearl@nih.gov

    2014-01-20

    Classical inbred mice are extensively used for virus research. However, we recently found that some wild-derived inbred mouse strains are more susceptible than classical strains to monkeypox virus. Experiments described here indicated that the 50% lethal dose of vaccinia virus (VACV) and cowpox virus (CPXV) were two logs lower in wild-derived inbred CAST/Ei mice than classical inbred BALB/c mice, whereas there was little difference in the susceptibility of the mouse strains to herpes simplex virus. Live bioluminescence imaging was used to follow spread of pathogenic and attenuated VACV strains and CPXV virus from nasal passages to organs in the chest and abdomen of CAST/Ei mice. Luminescence increased first in the head and then simultaneously in the chest and abdomen in a dose-dependent manner. The spreading kinetics was more rapid with VACV than CPXV although the peak photon flux was similar. These data suggest advantages of CAST/Ei mice for orthopoxvirus studies. - Highlights: • Wild-derived inbred CAST/Ei mice are susceptible to vaccinia virus and cowpox virus. • Morbidity and mortality from orthopoxviruses are greater in CAST/Ei than BALB/c mice. • Morbidity and mortality from herpes simplex virus type 1 are similar in both mice. • Imaging shows virus spread from nose to lungs, abdominal organs and brain. • Vaccinia virus spreads more rapidly than cowpox virus.

  13. Sensitivity of GC-EI/MS, GC-EI/MS/MS, LC-ESI/MS/MS, LC-Ag(+) CIS/MS/MS, and GC-ESI/MS/MS for analysis of anabolic steroids in doping control.

    Science.gov (United States)

    Cha, Eunju; Kim, Sohee; Kim, Ho Jun; Lee, Kang Mi; Kim, Ki Hun; Kwon, Oh-Seung; Lee, Jaeick

    2015-01-01

    This study compared the sensitivity of various separation and ionization methods, including gas chromatography with an electron ionization source (GC-EI), liquid chromatography with an electrospray ionization source (LC-ESI), and liquid chromatography with a silver ion coordination ion spray source (LC-Ag(+) CIS), coupled to a mass spectrometer (MS) for steroid analysis. Chromatographic conditions, mass spectrometric transitions, and ion source parameters were optimized. The majority of steroids in GC-EI/MS/MS and LC-Ag(+) CIS/MS/MS analysis showed higher sensitivities than those obtained with other analytical methods. The limits of detection (LODs) of 65 steroids by GC-EI/MS/MS, 68 steroids by LC-Ag(+) CIS/MS/MS, 56 steroids by GC-EI/MS, 54 steroids by LC-ESI/MS/MS, and 27 steroids by GC-ESI/MS/MS were below cut-off value of 2.0 ng/mL. LODs of steroids that formed protonated ions in LC-ESI/MS/MS analysis were all lower than the cut-off value. Several steroids such as unconjugated C3-hydroxyl with C17-hydroxyl structure showed higher sensitivities in GC-EI/MS/MS analysis relative to those obtained using the LC-based methods. The steroids containing 4, 9, 11-triene structures showed relatively poor sensitivities in GC-EI/MS and GC-ESI/MS/MS analysis. The results of this study provide information that may be useful for selecting suitable analytical methods for confirmatory analysis of steroids. Copyright © 2015 John Wiley & Sons, Ltd.

  14. A hybrid genetic linkage map of two ecologically and morphologically divergent Midas cichlid fishes (Amphilophus spp.) obtained by massively parallel DNA sequencing (ddRADSeq).

    Science.gov (United States)

    Recknagel, Hans; Elmer, Kathryn R; Meyer, Axel

    2013-01-01

    Cichlid fishes are an excellent model system for studying speciation and the formation of adaptive radiations because of their tremendous species richness and astonishing phenotypic diversity. Most research has focused on African rift lake fishes, although Neotropical cichlid species display much variability as well. Almost one dozen species of the Midas cichlid species complex (Amphilophus spp.) have been described so far and have formed repeated adaptive radiations in several Nicaraguan crater lakes. Here we apply double-digest restriction-site associated DNA sequencing to obtain a high-density linkage map of an interspecific cross between the benthic Amphilophus astorquii and the limnetic Amphilophus zaliosus, which are sympatric species endemic to Crater Lake Apoyo, Nicaragua. A total of 755 RAD markers were genotyped in 343 F(2) hybrids. The map resolved 25 linkage groups and spans a total distance of 1427 cM with an average marker spacing distance of 1.95 cM, almost matching the total number of chromosomes (n = 24) in these species. Regions of segregation distortion were identified in five linkage groups. Based on the pedigree of parents to F(2) offspring, we calculated a genome-wide mutation rate of 6.6 × 10(-8) mutations per nucleotide per generation. This genetic map will facilitate the mapping of ecomorphologically relevant adaptive traits in the repeated phenotypes that evolved within the Midas cichlid lineage and, as the first linkage map of a Neotropical cichlid, facilitate comparative genomic analyses between African cichlids, Neotropical cichlids and other teleost fishes.

  15. The EIS (Environmental Impact Statement) Process in Relation to the Proposed Naval Task Force at Everett, Washington,

    Science.gov (United States)

    1983-01-01

    decision before filing the EA. Also, the transfer of fuel and arms and the change in economic and social enviromental effects warranted an EIS. Facts: The...must deal with many of the same environmental, social , and economic problems that are evident. The basing of a Naval Task Force in Puget Sound stems from...which involves unresolved conflicts e. V.V..4 President OMB Cirua * NEPA of 1969 (42 U.S.C. 4321) CEQ/EIS Guidelines 40 CFR 1500-1508 . 7 Excuiv Ordc

  16. CDW-EIS model for single-electron capture in ion-atom collisions involving multielectronic targets

    International Nuclear Information System (INIS)

    Abufager, P N; MartInez, A E; Rivarola, R D; Fainstein, P D

    2004-01-01

    A generalization of the continuum distorted wave eikonal initial state (CDW-EIS) approximation, for the description of single-electron capture in ion-atom collisions involving multielectronic targets is presented. This approximation is developed within the framework of the independent electron model taking particular care of the representation of the bound and continuum target states. Total cross sections for single-electron capture from the K-shell of He, Ne and Ar noble gases by impact of bare ions are calculated. Present results are compared to previous CDW-EIS ones and to experimental data

  17. AN IMPLEMENTATION OF EIS-SVM CLASSIFIER USING RESEARCH ARTICLES FOR TEXT CLASSIFICATION

    Directory of Open Access Journals (Sweden)

    B Ramesh

    2016-04-01

    Full Text Available Automatic text classification is a prominent research topic in text mining. The text pre-processing is a major role in text classifier. The efficiency of pre-processing techniques is increasing the performance of text classifier. In this paper, we are implementing ECAS stemmer, Efficient Instance Selection and Pre-computed Kernel Support Vector Machine for text classification using recent research articles. We are using better pre-processing techniques such as ECAS stemmer to find root word, Efficient Instance Selection for dimensionality reduction of text data and Pre-computed Kernel Support Vector Machine for classification of selected instances. In this experiments were performed on 750 research articles with three classes such as engineering article, medical articles and educational articles. The EIS-SVM classifier provides better performance in real-time research articles classification.

  18. Uus töölpeinguseadus : nagu Soomes lama ajal? Ei, veel karmim / Maret Maripuu, Tarmo Kriis, Peep Peterson ; interv. Külli-Riin Tigasson

    Index Scriptorium Estoniae

    Maripuu, Maret, 1974-

    2008-01-01

    Uue töölepingu seaduse eelnõust. Vestlusringis on sotsiaalminister Maret Maripuu, Eesti tööandjate keskliidu juhataja Tarmo Kriis ja transpordi ametiühingu juhatuse esimees Peep Peterson. Lisatud: mida eelnõu muudab? ; ametiühingute keskliidu juhi Harri Taliga kommentaar: dzhungliseaduste tagasitulek? ; Helmes ASi nõukogu esimehe Jaan Pillesaare kommentaar: praegune seadus on tobe

  19. Eesmärk ei pühenda iga abinõu. Eetiline investor tunneb vastutust / Kadri Bank

    Index Scriptorium Estoniae

    Bank, Kadri

    2011-01-01

    ÜRO vastutustundliku investeerimise programmiga liitunud Limestone Fundsi investeerimispõhimõte on mitte finantseerida ettevõtteid, kelle tegevus on ühiskonna jätkusuutliku arenguga vastuolus. Selle juht Alvar Roosimaa ei näe n.-ö. tavalise ja eetilise investeeringu pikkuse ja kasumlikkuse juures mingit erinevust

  20. Electrochemical impedance spectroscopy (EIS) as a tool for measuring corrosion of polymer-coated fasteners used in treated wood

    Science.gov (United States)

    Samuel L. Zelinka; Lorraine Ortiz-Candelaria; Donald S. Stone; Douglas R. Rammer

    2009-01-01

    Currently, many of the polymer-coated fasteners on the market are designed for improved corrosion performance in treated wood; yet, there is no way to evaluate their corrosion performance. In this study, a common technique for measuring the corrosion performance of polymer-coated metals, electrochemical impedance spectroscopy (EIS), was used to evaluate commercial...

  1. 75 FR 2133 - Construction and Operation of the Quartzsite Solar Energy Project, La Paz County, AZ (DOE/EIS-0440)

    Science.gov (United States)

    2010-01-14

    ... Quartzsite Solar Energy Project, La Paz County, AZ (DOE/EIS-0440) AGENCY: Western Area Power Administration... proposed Quartzsite Solar Energy Project (Project) in La Paz County, near Quartzsite, Arizona. Quartzsite Solar Energy, LLC (QSE) has applied to Western to interconnect the proposed Project to Western's power...

  2. 77 FR 52108 - Notice of Withdrawal of the Notice of Intent To Prepare an Environmental Impact Statement (EIS...

    Science.gov (United States)

    2012-08-28

    ... Environmental Policy Act (NEPA) activities with the Bureau of Land Management as the Lead Agency to secure the... Intent To Prepare an Environmental Impact Statement (EIS) for the Proposed Sheep Mountain Parkway... Multimodal Transportation Project, which includes highway, transit, and non-motorized trail components in...

  3. 33 CFR 230.7 - Actions normally requiring an Environmental Assessment (EA) but not necessarily an EIS.

    Science.gov (United States)

    2010-07-01

    .... (d) Construction and Operations and Maintenance. Changes in environmental impacts which were not considered in the project EIS or EA. Examples are changes in pool level operations, use of new disposal areas, location of bank protection works, etc. (e) Real Estate Management and Disposal Actions. (1) Disposal of a...

  4. 78 FR 32240 - Notice of Inent (NOI) To Prepare an Environmental Impact Statement (EIS) for the Oro Verde Solar...

    Science.gov (United States)

    2013-05-29

    ... DEPARTMENT OF DEFENSE Notice of Inent (NOI) To Prepare an Environmental Impact Statement (EIS) for the Oro Verde Solar Project at Edwards Air Force Base and County of Kern, CA AGENCY: Department of the... with the development of the Oro Verde Solar Project (OVSP) on Edwards AFB. The OVSP is a solar...

  5. 75 FR 2138 - Interconnection of the Proposed Hermosa West Wind Farm Project, Wyoming (DOE/EIS-0438)

    Science.gov (United States)

    2010-01-14

    ... in accordance with the National Environmental Policy Act of 1969 (NEPA), U.S. Department of Energy... Open Access Transmission Service Tariff (Tariff). This EIS will address Western's Federal action of..., Office of NEPA Policy and Compliance, GC-54, U.S. Department of Energy, 1000 Independence Avenue, SW...

  6. Kuidas saab Tallinna Vee brittidelt tagasi osta, kui nad ei taha müüa? / Andres Reimer

    Index Scriptorium Estoniae

    Reimer, Andres

    2009-01-01

    Autori sõnul peavad tõsiselt võetavad analüütikud ja arvamusliidrid Tallinna Vee aktsiate linnale ostmist majanduslikult põhjendamata sammuks, mis tooks kaasa suure laenukoorma, mille lõpuks maksavad kinni tallinlased. Asjatundjate hinnangul ei paista Tallinna Vee omanikel olevat ühtegi põhjust, miks nad tahaksid firma aktsiaid müüa

  7. 76 FR 53705 - Notice To Rescind a Notice of Intent To Prepare an Environmental Impact Statement (EIS), Ada...

    Science.gov (United States)

    2011-08-29

    ... new concept are not significant and do not warrant an EIS. Recommendations for improvements along this... with several concepts derived from previous planning efforts. Then a wide range of route options were...) technology such as closed caption television cameras, speed detectors, and other hardware and software...

  8. 78 FR 4134 - Notice of Intent To Prepare An Environmental Impact Statement (EIS) On the Proposal To Relocate...

    Science.gov (United States)

    2013-01-18

    ... Proposal To Relocate the 18th Aggressor Squadron From Eielson Air Force Base (EAFB), Alaska to Joint Base... Eielson AFB, AK AGENCY: Pacific Air Forces, United States Air Force, DOD. ACTION: Notice of Intent... Statement (EIS) considering a proposal to relocate the 18th Aggressor Squadron from Eielson AFB to Joint...

  9. Venemaa ei tahtnud G8-le läinud Eesti ajakirjanikke üle piiri lasta / Krister Paris

    Index Scriptorium Estoniae

    Paris, Krister, 1977-

    2006-01-01

    Vene piirivalve hoidis Ivangorodis mitu tundi kinni G-8 tippkohtumisele akrediteeringu saanud kolme Eesti ajakirjanikku. Vt. samas: Venemaa WTO-sse veel ei saa, trump on tuumaenergial; Tanel Mazur. Globaliseerumisvastased saadeti pärast vangistust tagasi Eestisse. Lisad: Meelt jõuti avaldada vaid kaks minutit; Lukashenko vastased kiirelt türmi

  10. 77 FR 58531 - Notice of Intent To Prepare a Joint Environmental Impact Statement (EIS) for the Gateway Pacific...

    Science.gov (United States)

    2012-09-21

    ... social, economic, and environmental impacts of the projects and is intended to be sufficient in scope to... across streams. The Corps is preparing an EIS to analyze the potential social, economic, and...; land use; and aesthetics. c. The Corps will serve as the lead agency for compliance with NEPA, and...

  11. Blocking epithelial-to-mesenchymal transition in glioblastoma with a sextet of repurposed drugs: the EIS regimen.

    Science.gov (United States)

    Kast, Richard E; Skuli, Nicolas; Karpel-Massler, Georg; Frosina, Guido; Ryken, Timothy; Halatsch, Marc-Eric

    2017-09-22

    This paper outlines a treatment protocol to run alongside of standard current treatment of glioblastoma- resection, temozolomide and radiation. The epithelial to mesenchymal transition (EMT) inhibiting sextet, EIS Regimen, uses the ancillary attributes of six older medicines to impede EMT during glioblastoma. EMT is an actively motile, therapy-resisting, low proliferation, transient state that is an integral feature of cancers' lethality generally and of glioblastoma specifically. It is believed to be during the EMT state that glioblastoma's centrifugal migration occurs. EMT is also a feature of untreated glioblastoma but is enhanced by chemotherapy, by radiation and by surgical trauma. EIS Regimen uses the antifungal drug itraconazole to block Hedgehog signaling, the antidiabetes drug metformin to block AMP kinase (AMPK), the analgesic drug naproxen to block Rac1, the anti-fibrosis drug pirfenidone to block transforming growth factor-beta (TGF-beta), the psychiatric drug quetiapine to block receptor activator NFkB ligand (RANKL) and the antibiotic rifampin to block Wnt- all by their previously established ancillary attributes. All these systems have been identified as triggers of EMT and worthy targets to inhibit. The EIS Regimen drugs have a good safety profile when used individually. They are not expected to have any new side effects when combined. Further studies of the EIS Regimen are needed.

  12. 76 FR 2903 - Interconnection of the Proposed Hyde County Wind Energy Center Project (DOE/EIS-0461), and...

    Science.gov (United States)

    2011-01-18

    ... Wind Energy Center Project (DOE/EIS-0461), and Proposed Crowned Ridge Wind Energy Center Project (DOE... to prepare environmental impact statements (EISs) for the Hyde County Wind Energy Center Project and the Crowned Ridge Wind Energy Center Project in the Federal Register on November 30, 2010. Both...

  13. Läti riik ei suuda IMF-i nõuet mingi hinnaga täita / Kaivo Kopli

    Index Scriptorium Estoniae

    Kopli, Kaivo

    2009-01-01

    Isegi ametiasutuste palkade ja kulude vähendamisel 40% võrra ei suudaks Läti järgida viieprotsendise puudujäägi nõuet, mille täitmise korral on IMF valmis andma edasisi laene. Valitsuse siht on jõuda sel aastal seitsmeprotsendise defitsiidini

  14. PV Interneurons: Critical Regulators of E/I Balance for Prefrontal Cortex-Dependent Behavior and Psychiatric Disorders

    Directory of Open Access Journals (Sweden)

    Brielle R. Ferguson

    2018-05-01

    Full Text Available Elucidating the prefrontal cortical microcircuit has been challenging, given its role in multiple complex behaviors, including working memory, cognitive flexibility, attention, social interaction and emotional regulation. Additionally, previous methodological limitations made it difficult to parse out the contribution of certain neuronal subpopulations in refining cortical representations. However, growing evidence supports a fundamental role of fast-spiking parvalbumin (PV GABAergic interneurons in regulating pyramidal neuron activity to drive appropriate behavioral responses. Further, their function is heavily diminished in the prefrontal cortex (PFC in numerous psychiatric diseases, including schizophrenia and autism. Previous research has demonstrated the importance of the optimal balance of excitation and inhibition (E/I in cortical circuits in maintaining the efficiency of cortical information processing. Although we are still unraveling the mechanisms of information representation in the PFC, the E/I balance seems to be crucial, as pharmacological, chemogenetic and optogenetic approaches for disrupting E/I balance induce impairments in a range of PFC-dependent behaviors. In this review, we will explore two key hypotheses. First, PV interneurons are powerful regulators of E/I balance in the PFC, and help optimize the representation and processing of supramodal information in PFC. Second, diminishing the function of PV interneurons is sufficient to generate an elaborate symptom sequelae corresponding to those observed in a range of psychiatric diseases. Then, using this framework, we will speculate on whether this circuitry could represent a platform for the development of therapeutic interventions in disorders of PFC function.

  15. Flawlessi tankeriga sõitnud Küprose firma ei võta merereostuse tekitamist omaks / Martin Hanson

    Index Scriptorium Estoniae

    Hanson, Martin, 1984-

    2006-01-01

    Flawlessi tankeriga opereerivat Küprose firmat Hanseatic Shipping ei saa reostuses süüdistada, sest nemad vedasid rasket kütteõli, kuid Lääne-Eesti rannikult leiti pooltahke õlimass. Vt. samas: Piret Reiljan. Alambra reostuse puhul jäi Eestil trahv saamata; Prokuratuuril sadu kahtlusaluseid

  16. Chromospheric Evaporation in an M1.8 Flare Observed by the Extreme-ultraviolet Imaging Spectrometer (EIS) on Hinode

    Science.gov (United States)

    Doschek, G. A.; Warren, H. P.

    2012-12-01

    We discuss observations of chromospheric evaporation for a flare that occurred on 9 March 2012 near 03:30 UT obtained from the Extreme-ultraviolet Imaging Spectrometer (EIS) on the Hinode spacecraft. This was a multiple event with a strong energy input that reached the M1.8 class when observed by EIS. EIS was in raster mode and fortunately the slit reached almost the exact location of a significant energy input. Also, fortunately EIS obtained a full-CCD spectrum of the flare, i.e., the entire CCD was readout so that data were obtained for about the 500 lines identified in the EIS wavelength ranges. Chromospheric evaporation characterized by 150-200 km/s upflows was observed in several locations in multi-million degree spectral lines of flare ions such as Fe XXII, Fe XXIII, Fe XXIV, with simultaneous 20 - 60 km/s upflows in a host of million degree coronal lines from ions such as Fe XI - Fe XVI. The behavior of cooler, transition region ions such as O VI, Fe VIII, He II, and Fe X is more complex. At a point close to strong energy input, the flare ions reveal an isothermal source with a temperature close to 14 MK. At this point there is a strong downflow in cooler active region lines from ions such as Fe XIII and Fe XIV. Electron densities were obtained from density sensitive lines ratios from Fe XIII and Fe XIV. The results to be presented are refined from the preliminary data given above and combined with context AIA observations for a comparison with predictions of models of chromospheric evaporation as envisaged in the Standard Flare Model.

  17. "Kriitiline arhitektuur" ja selle vastased / George Baird

    Index Scriptorium Estoniae

    Baird, George

    2010-01-01

    Ameerika kriitilisest arhitektuurist ja uuest projektiivsest arhitektuurist, mida ei saa arendada ilma projektiivse teooria toeta. Selleta muutuks uus arhitektuur autori arvates kiiresti lihtsalt pragmaatiliseks ja lihtsalt dekoratiivseks

  18. Populizm dvadtsat pervogo veka / Roberto Lasserna

    Index Scriptorium Estoniae

    Lasserna, Roberto

    2007-01-01

    Venezuelas, Boliivias ja Ecuadoris on tekkimas uus poliitiline liikumine, mida nende maade presidendid nimetavad 21. sajandi sotsialismiks, mis tegelikkuses ei erine milleski 20. sajandi sotsialismist

  19. Interaction of cysteine and copper ions on the surface of iron: EIS, polarization and XPS study

    International Nuclear Information System (INIS)

    El-Deab, Mohamed S.

    2011-01-01

    Highlights: → The current study demonstrates a comprehensive study for Cysteine + Cu(II) ions as an efficient inhibitor as demonstrated by EIS, XPS and potentiodynamic polarization measurements, in addition to traditional weight loss measurements. → The novelty of the current work originates from the combined use of an eco-friendly compound (i.e., cysteine) with a minute amount of copper ions (in the micro molar range) as a corrosion inhibitor for low carbon steel in acidic medium. To this end, cysteine shows only moderate inhibition ca. 60% for iron which jumps up to more than 95% in the presence of micro molar range of Cu(II) ions. → Cysteine-Cu(II) blends are found superior to benzotriazole (BTAH)-Cu(II) blends in terms of their long-term stability in addition to the avoidance of the use of the well-reported highly toxic BTAH. - Abstract: This study addresses the enhancing effect of copper ions on the inhibition efficiency (IE) of cysteine (an eco-friendly compound) against the corrosion of iron in 0.5 M sulphuric acid. Electrochemical impedance spectroscopy (EIS) data revealed a significant increase in the polarization resistance (R p ) of the iron/solution interface in the presence of cysteine and Cu(II) ions instead of cysteine alone. That is, IE of 95% is obtained in the presence of 5 mM cysteine and 25 μM Cu(II) ions, compared to 66% in absence of Cu(II) ions. Moreover, electrochemical polarization measurements indicate that cysteine and Cu(II) ions blends act as mixed-type inhibitors for the corrosion of iron. The formation of Cu(I)-cysteinate complex and/or cysteine SAM at Cu atop the iron surface (as evident from X-ray photoelectron spectroscopy (XPS)) blocks the underlying iron surface and imparts a pronounced protection against its corrosion. IE of cysteine-Cu(II) blend remains effectively unchanged with immersion time indicating its high stability in the used acidic medium.

  20. Evaluarea performanţei heterozis la analogii MRf ai liniilor consangvinizate de porumb

    Directory of Open Access Journals (Sweden)

    PARTAS Eugenia

    2015-12-01

    Full Text Available The paper presents the multiannual results obtained from the evaluation of heterosis performance of MRf analogs in expression of 16 morphological and agronomic traits. The results revealed that the hybrids with MRf pollinators in comparison with the original version present a richer tassel in lateral branches and significantly lower values for 9 out of 15 evaluated traits, especially in the expression of plant length, length of ear, number of grains per rowand tassel peduncle length. The backcrossed fertile plants in MRf analog contributed to the differentiation of descendants in terms of heterosis performance of grain yield in the evaluated 2-4 consecutive generations, but the selection of MRf descendants with significant higher values did not contribute to the improvement of the analog in this respect. Rezumat. În lucrare sunt prezentate rezultatele multianuale obţinute la evaluarea performanţei heterozis a analogilor MRf la expresia a 16 indici morfologici şi agronomici. Rezultatele obţinute denotă că hibrizii cu polenizatori MRf se prezintă cu panicul mai bogat în ramificaţii laterale în comparaţie cu varianta originală a hibridului şi cu valori semnificativ mai mici la expresia a 9 din 15 caracteristici evaluate, mai ales la expresia taliei plantelor, lungimea ştiuletelui, numărul de boabe pe rând şi lungimea pedunculului la panicul. Retroîncrucişarea plantelor fertile în analogul MRf a contribuit la diferenţierea descendenţelor din punct de vedere al performanţei heterozis la producţia de boabe în 2-4 generaţii consecutive de evaluare, iar selecţia descendenţelor Rf cu valori superioare originalei nu a contribuit la îmbunătăţirea analogului în acest sens.

  1. ACCELERATING WAVES IN POLAR CORONAL HOLES AS SEEN BY EIS AND SUMER

    International Nuclear Information System (INIS)

    Gupta, G. R.; Banerjee, D.; Teriaca, L.; Solanki, S.; Imada, S.

    2010-01-01

    We present EIS/Hinode and SUMER/SOHO observations of propagating disturbances detected in coronal lines in inter-plume and plume regions of a polar coronal hole. The observation was carried out on 2007 November 13 as part of the JOP196/HOP045 program. The SUMER spectroscopic observation gives information about fluctuations in radiance and on both resolved (Doppler shift) and unresolved (Doppler width) line-of-sight velocities, whereas EIS 40'' wide slot images detect fluctuations only in radiance but maximize the probability of overlapping field of view between the two instruments. From distance-time radiance maps, we detect the presence of propagating waves in a polar inter-plume region with a period of 15-20 minutes and a propagation speed increasing from 130 ± 14 km s -1 just above the limb to 330 ± 140 km s -1 around 160'' above the limb. These waves can be traced to originate from a bright region of the on-disk part of the coronal hole where the propagation speed is in the range of 25 ± 1.3 to 38 ± 4.5 km s -1 , with the same periodicity. These on-disk bright regions can be visualized as the base of the coronal funnels. The adjacent plume region also shows the presence of propagating disturbances with the same range of periodicity but with propagation speeds in the range of 135 ± 18 to 165 ± 43 km s -1 only. A comparison between the distance-time radiance map of the two regions indicates that the waves within the plumes are not observable (may be getting dissipated) far off-limb, whereas this is not the case in the inter-plume region. A correlation analysis was also performed to find out the time delay between the oscillations at several heights in the off-limb region, finding results consistent with those from the analysis of the distance-time maps. To our knowledge, this result provides first spectroscopic evidence of the acceleration of propagating disturbances in the polar region close to the Sun (within 1.2 R/R sun ), which provides clues to the

  2. Evaluation of accelerated aging procedures of painted galvanised steels by EIS

    Energy Technology Data Exchange (ETDEWEB)

    Fedrizzi, L. [Department of Chemical Science and Technology, University of Udine, Via Cotonificio 108, 33100 Udine (Italy)]. E-mail: lorenzo.fedrizzi@uniud.it; Bergo, A. [Department of ICMMPM, University of Rome ' La Sapienza' , Via Eudossiana 18, 00184 Rome (Italy); Fanicchia, M. [Department of ICMMPM, University of Rome ' La Sapienza' , Via Eudossiana 18, 00184 Rome (Italy)

    2006-01-20

    Coil-coated sheets are usually cut and shaped or deep drawn to obtain the final profile of the manufacture. Mechanical deformation can affect the barrier properties of an organic coating and the adhesion to the substrate, thus accelerating degradation by natural weathering. UV radiations too can deeply affect the barrier properties of organic coatings and contribute along with rain, snow, thermal and hygrometric cycles and other factors to a fast decaying of the anticorrosive properties of painted systems. In this work some coil coating products for outdoor exposure, were subjected to the combined action of UV irradiation and mechanical deformation in order to simulate some of the stress occurring in their actual use. After mechanical deformation and UV irradiation, samples were exposed to a proper thermal cycle in order to accelerate water uptake and to discriminate in very short time among different formulations. Electrochemical impedance spectroscopy (EIS) was used to monitor the evolution of the systems during the accelerated aging. Qc and Rp (i.e. the constant phase element describing the dielectric properties and the ionic resistance of the coating) were selected to describe the protective system evolution. Adhesive and barrier properties were monitored and discussed during the combined thermal-mechanical and photo-oxidative aging.

  3. Electrochemical Polishing Applications and EIS of a Vitamin B4-Based Ionic Liquid

    International Nuclear Information System (INIS)

    Wixtrom, Alex I.; Buhler, Jessica E.; Reece, Charles E.; Abdel-Fattah, Tarek M.

    2013-01-01

    Modern particle accelerators require minimal interior surface roughness for Niobium superconducting radio frequency (SRF) cavities. Polishing of the Nb is currently achieved via electrochemical polishing with concentrated mixtures of sulfuric and hydrofluoric acids. This acid-based approach is effective at reducing the surface roughness to acceptable levels for SRF use, but due to acid-related hazards and extra costs (including safe disposal of used polishing solutions), an acid-free method would be preferable. This study focuses on an alternative electrochemical polishing method for Nb, using a novel ionic liquid solution containing choline chloride, also known as Vitamin B 4 (VB 4 ). Potentiostatic electrochemical impedance spectroscopy (EIS) was also performed on the VB4-based system. Nb polished using the VB4-based method was found to have a final surface roughness comparable to that achieved via the acid-based method, as assessed by atomic force microscopy (AFM). These findings indicate that acid-free VB 4 -based electrochemical polishing of Nb represents a promising replacement for acid-based methods of SRF cavity preparation

  4. 1992 Columbia River Salmon Flow Measures Options Analysis/EIS : Appendices.

    Energy Technology Data Exchange (ETDEWEB)

    1992-01-01

    This Options Analysis/Environmental Impact Statement (OA/EIS) identifies, presents effects of, and evaluates the potential options for changing instream flow levels in efforts to increase salmon populations in the lower Columbia and Snake rivers. The potential actions would be implemented during 1992 to benefit juvenile and adult salmon during migration through eight run-of-river reservoirs. The Corps of Engineers (Corps) prepared this document in cooperation with the Bonneville Power Administration and the Bureau of Reclamation. The US Fish and Wildlife Service (FWS) is a participating agency. The text and appendices of the document describe the characteristics of 10 Federal projects and one private water development project in the Columbia River drainage basin. Present and potential operation of these projects and their effects on the salmon that spawn and rear in the Columbia and Snake River System are presented. The life history, status, and response of Pacific salmon to current environmental conditions are described. The document concludes with an evaluation of the potential effects that could result from implementing proposed actions. The conclusions are based on evaluation of existing data, utilization of numerical models, and application of logical inference. This volume contains the appendices.

  5. EIS and potentiodynamic polarization studies on immiscible monotectic Al–In alloys

    International Nuclear Information System (INIS)

    Osório, Wislei R.; Freitas, Emmanuelle S.; Garcia, Amauri

    2013-01-01

    Highlights: • The Al–In alloy microstructure is characterized by In droplets spread in an Al matrix. • The scale of phases forming the microstructure affect the electrochemical behavior. • Larger interphase spacing/droplet diameter is related to higher corrosion resistance. • The deleterious effect in corrosion resistance is due to strains and galvanic cells. -- Abstract: The electrochemical behavior of monotectic Al–In alloys is experimentally investigated. Electrochemical impedance spectroscopy (EIS), potentiodynamic anodic polarization techniques and an equivalent circuit analysis were used to evaluate the corrosion response in a stagnant and naturally aerated 0.5 M NaCl solution at 25 °C. It was found that a better galvanic protection can be provided for microstructures having indium droplets of larger diameters and larger interphase spacings. From five samples extracted along the length of a directionally solidified Al–In casting, that having smallest interphase spacing (λ = 18 μm) and droplet diameter (d = 0.7 μm) had its corrosion resistance significantly decreased (about 2 and 3 times in terms of the current density and polarization resistance) when compared with that of the sample having the coarsest microstructure (λ = 60 μm and d = 2.5 μm). Such behavior is attributed to both localized strains between aluminum and indium boundaries and the corrosion potential of the indium particles

  6. An assessment of the water management program proposed in the Ranger EIS and its environmental implications

    International Nuclear Information System (INIS)

    Davy, D.R.

    1976-01-01

    An assessment of the water management program proposed in the Ranger EIS has three components: a) a statement of water quality criteria and standards that the program must meet, b) a set of calculations based on the best available estimates, that compares the expected levels of waste with the standards set for the release, c) the plan of the surveillance program aimed at demonstrating compliance with these standards and at revealing deficiencies in the choice of criteria, the derivation of standards from them and unforseen departures from expectation. Standards are suggested for the operation of the Ranger mines based on the most restrictive criterion out of: (i) acute toxicity tests carried out on organisms and water from the Magela Creek combined with application factors recommended by AWRC, (ii) the results on indicator species and biological diversity indices for the Finniss river, (iii) requirements for agricultural and pastoral use, (iv) the requirements for portable water. It is expected that the program proposed by Ranger will meet these standards and it is concluded that planning for a comprehensive environmental program is adequate. (author)

  7. Washington Windplant No. 1: Botanical resources field survey. Appendix B to Washington Windplant No. 1 EIS

    International Nuclear Information System (INIS)

    1994-12-01

    KENETECH Windpower, Inc., has applied to Klickitat County for a conditional use permit to construct and operate a 115 Megawatt windfarm on an approximately 5110 hectare (12,630 acre) site in the Columbia Hills near Goldendale, Washington. A transmission services agreement between the Bonneville Power Administration (BPA) and utilities purchasing the Project's output will also be required. Klickitat County and BPA initiated the preparation of a joint SEPA/NEPA Environmental Impact Statement, under the authority of the Washington State Environmental Policy Act and the National Environmental Policy Act. The EIS addresses, among other issues, the Project's potential impact on rare, threatened or endangered, and sensitive plant species and communities as well as plant species of potential cultural importance. A field survey along potential impact corridors (turbine strings, roadways, and the transmission line alignment) was conducted between April and June, 1994 in order to identify rare plant species, high-quality native plant communities, and plant species of potential cultural importance present in these corridors. In addition, habitat maps of the entire 5110-ha project area were field verified. This report contains the results of that survey and an assessment of the potential project impacts

  8. 1992 Columbia River salmon flow measures Options Analysis/EIS: Appendices

    International Nuclear Information System (INIS)

    1992-01-01

    This Options Analysis/Environmental Impact Statement (OA/EIS) identifies, presents effects of, and evaluates the potential options for changing instream flow levels in efforts to increase salmon populations in the lower Columbia and Snake rivers. The potential actions would be implemented during 1992 to benefit juvenile and adult salmon during migration through eight run-of-river reservoirs. The Corps of Engineers (Corps) prepared this document in cooperation with the Bonneville Power Administration and the Bureau of Reclamation. The US Fish and Wildlife Service (FWS) is a participating agency. The text and appendices of the document describe the characteristics of 10 Federal projects and one private water development project in the Columbia River drainage basin. Present and potential operation of these projects and their effects on the salmon that spawn and rear in the Columbia and Snake River System are presented. The life history, status, and response of Pacific salmon to current environmental conditions are described. The document concludes with an evaluation of the potential effects that could result from implementing proposed actions. The conclusions are based on evaluation of existing data, utilization of numerical models, and application of logical inference. This volume contains the appendices

  9. Evaluation of accelerated aging procedures of painted galvanised steels by EIS

    International Nuclear Information System (INIS)

    Fedrizzi, L.; Bergo, A.; Fanicchia, M.

    2006-01-01

    Coil-coated sheets are usually cut and shaped or deep drawn to obtain the final profile of the manufacture. Mechanical deformation can affect the barrier properties of an organic coating and the adhesion to the substrate, thus accelerating degradation by natural weathering. UV radiations too can deeply affect the barrier properties of organic coatings and contribute along with rain, snow, thermal and hygrometric cycles and other factors to a fast decaying of the anticorrosive properties of painted systems. In this work some coil coating products for outdoor exposure, were subjected to the combined action of UV irradiation and mechanical deformation in order to simulate some of the stress occurring in their actual use. After mechanical deformation and UV irradiation, samples were exposed to a proper thermal cycle in order to accelerate water uptake and to discriminate in very short time among different formulations. Electrochemical impedance spectroscopy (EIS) was used to monitor the evolution of the systems during the accelerated aging. Qc and Rp (i.e. the constant phase element describing the dielectric properties and the ionic resistance of the coating) were selected to describe the protective system evolution. Adhesive and barrier properties were monitored and discussed during the combined thermal-mechanical and photo-oxidative aging

  10. MiDAS I (mild Decompression Alternative to Open Surgery): a preliminary report of a prospective, multi-center clinical study.

    Science.gov (United States)

    Chopko, Bohdan; Caraway, David L

    2010-01-01

    Neurogenic claudication due to lumbar spinal stenosis is a common problem that can be caused by many factors including hypertrophic ligamentum flavum, facet hypertrophy, and disc protrusion. When standard medical therapies such as pain medication, epidural steroid injections, and physical therapy fail, or when the patient is unwilling, unable, or not severe enough to advance to more invasive surgical procedures, both physicians and patients are often left with a treatment dilemma. Patients in this study were treated with mild, an ultra-minimally invasive lumbar decompression procedure using a dorsal approach. The mild procedure is performed under fluoroscopic imaging to resect bone adjacent to, and achieve partial resection of, the hypertrophic ligamentum flavum with minimal disruption of surrounding muscular and skeletal structure. To assess the clinical application and patient safety and functional outcomes of the mild lumbar decompression procedure in the treatment of symptomatic central canal spinal stenosis. Multi-center, non-blinded, prospective clinical study. Fourteen US spine specialist practices. Between July 2008 and January 2010, 78 patients were enrolled in the MiDAS I Study and treated with the mild procedure for lumbar decompression. Of these patients, 6-week follow-up was available for 75 patients. Visual Analog Score (VAS), Oswestry Disability Index (ODI), Zurich Claudication Questionnaire (ZCQ), and SF-12v2 Health Survey. Outcomes were assessed at baseline and 6 weeks post-treatment. There were no major device or procedure-related complications reported in this patient cohort. At 6 weeks, the MiDAS I Study showed statistically and clinically significant reduction of pain as measured by VAS, ZCQ, and SF-12v2. In addition, improvement in physical function and mobility as measured by ODI, ZCQ, and SF-12v2 was statistically and clinically significant in this study. This is a preliminary report encompassing 6-week follow-up. There was no control group

  11. PERAN MP3EI BERBASIS ”NOT BUSINESS AS USUAL” UNTUK MENINGKATKAN DAYA SAING DAN PENYERAPAN TENAGA KERJA

    Directory of Open Access Journals (Sweden)

    Hardiansyah Nur Sahaya

    2015-12-01

    Full Text Available Indonesia, as a developing country, is currently facing a tremendous challenge. Global era can be an opportunity, a challenge, as well as a threat. In this globalization era, known as economic liberalization or free trade in services in particular labor. Indonesian workers are expected to be able to compete with workers from other countries. To meet the challenges of globalization workforce, the government has prepared MP3EI (Master Plan for the Acceleration and Expansion of Indonesia's Economic Development which is not based on common business. MP3EI is a government program that is made by considering the various advantages and potential, as well as the development challenges that Indonesia must face. However, in the implementation of the strategic role of MP3EI, there are still problems in terms of human resources, science and technology. Education focuses mainly on Java, less access to education, use of science and technology training, lack of infrastructure investment training. Therefore, we need a concrete solution in optimizing regional autonomy to address the education gap in each corridor, develop the concept of "one corridor, one potential school corridor". This concept is expected to optimize each economic corridor, regeneration and gradual training for cadres training centers, increasing government and private partnership (PPP in infrastructure investment in training through the implementation of regional autonomy.Indonesia sebagai bangsa yang sedang membangun, saat ini sedang menghadapi tantangan yang luar biasa. Era global dapat menjadi peluang, tantangan, sekaligus juga menjadi ancaman. Dalam era globalisasi yang dikenal dengan liberalisasi ekonomi atau perdagangan bebas khususnya bidang jasa tenaga kerja. Tenaga kerja Indonesia dituntut harus mampu bersaing dengan tenaga kerja dari negara lain. Untuk menjawab tantangan globalisasi tenaga kerja yang ada, pemerintah telah menyiapkan MP3EI (Masterplan Percepatan dan Perluasan

  12. Explosive Chromospheric Evaporation and Warm Rain in a GOES C3 Flare Observed by IRIS, Hinode/EIS, and RHESSI

    Science.gov (United States)

    Brosius, J. W.; Inglis, A. R.

    2017-12-01

    IRIS and Hinode/EIS observed a C3.1 flare in AR 12002 in stare mode on 2014 March 15.GOES observed the flare to start at 00:21:35 UT and peak at 00:26:30 UT. The IRIS slitwas pointed near the center of the flare while the EIS slit was pointed 35 arcsec westof the IRIS slit. About 4 minutes before the GOES flare start, the C II and Si IV lineintensities observed by IRIS became (and remained) significantly greater than theirpre-flare average values; this indicates that the flare had begun and that thechromosphere and transition region were involved. IRIS first detected significant,blueshifted Fe XXI emission at 00:22:42 UT, by which time the C II and Si IV lineintensities had increased by factors around 100 and their profiles were significantlyredshifted. This combination of simultaneous, cospatial blueshifted Fe XXI emissionwith redshifted C II and Si IV emission indicates explosive chromospheric evaporation.SDO's HMI observed a localized area of enhanced magnetic field strength toward thesouthernmost portion of the EIS slit's position that appears to be connected to theflare site by faint loops evident in AIA 131 A emission. EIS spectra at this locationreveal intensity enhancements by factors up to about 1.7 in the Fe XIV and Fe XVI lineemission, and the emergence of faint Fe XXIII emission that is too weak to measurevelocities. Emission lines from the two coronal ions show redshifts of about 9 km/saround 00:24:00 UT. The density sensitive line intensity ratio of Fe XIV 264.7/274.2observed by EIS reveals an increase of electron density from (1.03+/-0.20)X10^9 /cm^3before the flare to (3.58+/-0.68)X10^9 /cm^3 during the flare. This combination ofredshifted coronal line emission and increased coronal electron density is consistentwith explosively evaporated flare material observed by IRIS falling as warm rain andaccumulating in the remote area observed by EIS. A thermal/nonthermal fit to the hardX-ray spectrum observed by RHESSI yields a nonthermal energy injection

  13. Parameter changes during gradual flooding of a PEM fuel cell through EIS studies; Cambio en parametros de una celda de combustible PEM durante inundacion gradual mediante estudios de EIS

    Energy Technology Data Exchange (ETDEWEB)

    Cano Castillo, Ulises; Cruz Manzo, Samuel; Arriaga Hurtado, Gerardo [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico); Ortiz, Alondra; Orozco, German [Centro de Investigacion y Desarrollo Tecnologico en Electroquimica S.C. (CIDETEQ) (Mexico)

    2008-07-01

    The gradual flooding of a single PEM fuel cell was produced and Electrochemical Impedance Spectroscopy (EIS) measurements were realized in order to follow changes of the fuel cell impedance parameters. These changes were followed by using two equivalent circuit models: one simple model of the Randles type accounting for cathode and anode interfaces and a more complex model based on distributed elements, more suitable for porous electrodes in order to include protonic resistance of the catalyst layers. [Spanish] La inundacion gradual de una monocelda de combustible tipo PEM fue estudiada empleando espectroscopia de impedancia electroquimica (EIS), con el proposito de seguir cambios en los parametros de impedancia de la celda. Estos cambios fueron estudiados utilizando dos circuitos equivalentes: un modelo simple de tipo Randles, el cual considerara las interfaces del catodo y del anodo, y un modelo mas complejo basado en elementos distribuidos, el cual fuera adecuado para electrodos porosos, a fin de incluir la resistencia protonica de las capas catalizadoras.

  14. CRISPR/Cas9-Mediated Deletion of C1EIS Inhibits Chicken Embryonic Stem Cell Differentiation Into Male Germ Cells (Gallus gallus).

    Science.gov (United States)

    Zuo, Qisheng; Jin, Kai; Wang, Yingjie; Song, Jiuzhou; Zhang, Yani; Li, Bichun

    2017-08-01

    We previously found that C1EIS is preferentially expressed in Chicken spermatogonial stem cells (SSCs) by RNA sequencing (RNA-seq), so our current study focused on C1EIS's role in Chicken embryonic stem cells (ESCs) differentiation into male germ cells. We constructed a CRISPR/Cas9 vector targeting C1EIS. T7 endonuclease I (T7EI) digestion method and sequencing of TA cloning were used to detect the knock-out efficiency of the Single guide RNA (sgRNA) after the cas9/gRNA vector transfected into D fibroblasts 1(DF-1), ESCs, and Chicken embryos. The results showed that CRISPR/Cas9 gene knockout efficiency is about 40%. Differentiation of the targeted ESCs into SSCs was inhibited at the embryoid body stage due to C1EIS deficiency. Immunofluorescent staining revealed that the mutagenized ESCs (RA (Retinoic Acid) with C1EIS Knock out) expressed lower levels of integrin α6 and integrin β1 compared to wild type cells. Quantitative real-time PCR (QRT-PCR) revealed Oct4 and Sox2 expression significantly increased, contrarily integrin β1 and Stra8 expression significantly decreased than RA induced group and RA with C1EIS Overexpression. During retinoic acid-induced differentiation, knockout of C1EIS in ESCs inhibited formation of SSC-like cells, suggesting C1EIS plays a vital role in promoting differentiation of avian ESCs to SSCs by regulating expression of multiple pluripotency-related genes. J. Cell. Biochem. 118: 2380-2386, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  15. An EIS alternative for impedance measurement of a high temperature PEM fuel cell stack based on current pulse injection

    DEFF Research Database (Denmark)

    Jeppesen, Christian; Araya, Samuel Simon; Sahlin, Simon Lennart

    2017-01-01

    In this paper a method for estimating the fuel cell impedance is presented, namely the current pulse injection (CPI) method, which is well suited for online implementation. This method estimates the fuel cell impedance and unlike electrochemical impedance spectroscopy (EIS), it is simple...... to implement at a low cost. This makes it appealing as a characterization method for on-line diagnostic algorithms. In this work a parameter estimation method for estimation of equivalent electrical circuit (EEC) parameters, which is suited for on-line use is proposed. Tests on a 10 cell high temperature PEM...... fuel cell show that the method yields consistent results in estimating EEC parameters for different current pulse at different current loads, with a low variance. A comparison with EIS shows that despite its simplicity the response of CPI can reproduce well the impedance response of the high...

  16. Southeast Regional Wastewater Treatment Plant Facilities Improvements Project and Geysers Effluent Pipeline Project. Final EIR/EIS

    International Nuclear Information System (INIS)

    1994-01-01

    On May 26, 1994, the Lake County Sanitation District and the US Bureau of Land Management released for public review a Draft Environmental Impact Report/Environmental Impact Statement (EIR/EIS) on the proposed Southeast Regional Wastewater Treatment Plant Facilities Improvements Project and Geysers Effluent Pipeline Project. A minimum 45-day review and comment period began on that date and notices were published in the Federal Register. The public review and comment period closed on July 26, 1994. Public hearings on the Draft EIMIS were held in Lakeport, CA, on June 30 and July 14, 1994. The first part of this document contains copies of the written comments submitted on the Draft EIR/EIS. It also contains summary paraphrased comments of the public hearings. The second part of this document contains responses to the comments

  17. EIS pitting temperature determination of A182 nickel based alloy in simulated BWR environment containing dilute seawater

    International Nuclear Information System (INIS)

    Lavigne, Olivier; Shoji, Tetsuo; Takeda, Yoichi

    2014-01-01

    Graphical abstract: - Highlights: • Stable pitting events in function of the temperature are monitored by electrochemical impedance spectroscopy. • The pitting temperature for the nickel based alloy A182 in solution containing 450 ppm Cl − is defined as above 160 °C. • The presented method can be applied for others passive alloys as stainless steel in solution containing aggressive anions. - Abstract: A method based on electrochemical impedance spectroscopy (EIS) measurements to monitor the pitting temperature of passive alloys in a given media is developed in this communication. The pitting corrosion behavior of the nickel based alloy 182 in water containing 450 ppm by weight of chloride is presented in this study. The analysis of the EIS fit parameters from the proposed equivalent electrical circuit allows to determine the temperature from which stable pitting event occurs at open circuit potential. For the A182 sample this temperature is measured above 160 °C

  18. Neon-like Iron Ion Lines Measured in NIFS/Large Helical Device (LHD) and Hinode /EUV Imaging Spectrometer (EIS)

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, Tetsuya; Hara, Hirohisa [National Astronomical Observatory, National Institutes of Natural Sciences 2-21-1 Osawa Mitaka Tokyo, 181-8588 (Japan); Murakami, Izumi; Kato, Daiji; Morita, Shigeru [SOKENDAI (Graduate University for Advanced Studies) Hayama, Miura-gun, Kanagawa, 240-0193 (Japan); Sakaue, Hiroyuki A.; Suzuki, Chihiro; Tamura, Naoki [National Institute for Fusion Science, National Institutes of Natural Sciences 322-6 Oroshi-cho, Toki Gifu, 509-5292 (Japan); Yamamoto, Norimasa [Chubu University 1200 Matsumoto-cho, Kasugai Aichi, 487-0027 (Japan); Nakamura, Nobuyuki, E-mail: watanabe@uvlab.mtk.nao.ac.jp [The University of Electro-Communications 1-5-1 Chofugaoka, Chofu Tokyo, 182-8585 (Japan)

    2017-06-10

    Line intensities emerging from the Ne-sequence iron ion (Fe xvii) are measured in the laboratory, by the Large Helical Device at the National Institute for Fusion Science, and in the solar corona by the EUV Imaging Spectrometer (EIS) on board the Hinode mission. The intensity ratios of Fe xvii λ 204.6/ λ 254.8 are derived in the laboratory by unblending the contributions of the Fe xiii and xii line intensities. They are consistent with theoretical predictions and solar observations, the latter of which endorses the in-flight radiometric calibrations of the EIS instrument. The still remaining temperature-dependent behavior of the line ratio suggests the contamination of lower-temperature iron lines that are blended with the λ 204.6 line.

  19. EI Scale: an environmental impact assessment scale related to the construction materials used in the reinforced concrete

    Directory of Open Access Journals (Sweden)

    Gilson Morales

    2010-12-01

    Full Text Available This study aimed to create EI Scal, an environmental impact assessment scal, related to construction materials used in the reinforced concrete structure production. The main reason for that was based on the need to classify the environmental impact levels through indicators to assess the damage level process. The scale allowed converting information to estimate the environmental impact caused. Indicators were defined trough the requirements and classification criteria of impact aspects considering the eco-design theory. Moreover, the scale allowed classifying the materials and processes environmental impact through four score categories which resulted in a single final impact score. It was concluded that the EI scale could be cheap, accessible, and relevant tool for environmental impact controlling and reduction, allowing the planning and material specification to minimize the construction negative effects caused in the environment.

  20. Exploring EI in Belgium: a New Theoretical and Empirical Way to Deal with Environmental Conflicts in Urban Areas?

    OpenAIRE

    Lejeune, Zoé

    2013-01-01

    Environmental Inequalities (EI) –the unequal distribution of environmental goods and ‘bads’ among space and population– are a field of research at the crossroads of political science, socio-legal studies, and urban research. Unlike US Environmental Justice movement, environmental inequalities are not seen by actors, or studied, as a specific frame for action and collective mobilisation in Belgium in environmental matters. Environmental conflicts are however numerous in urban areas in Belgi...