Advanced Separations at SRS

International Nuclear Information System (INIS)

Thompson, M.C.

1998-03-01

The Savannah River Site (SRS) has many waste streams which are contaminated with radionuclides and/or hazardous materials which must be treated to remove the radioactivity (Cs, Sr, tritium, actinides) and hazardous components (polychlorinated biphenyls, cyanide, metal ions). This task provides test beds for ESP-developed separations materials and technologies using actual SRS waste streams. The work includes different SRS waste streams; high level waste solutions presently stored in underground tanks onsite, water recycled from the waste vitrification plant, and reactor basin water in excess facilities

SRS ECOLOGY ENVIRONMENTAL INFORMATION DOCUMENT

Energy Technology Data Exchange (ETDEWEB)

Wike, L; Doug Martin, D; Eric Nelson, E; Nancy Halverson, N; John Mayer, J; Michael Paller, M; Rodney Riley, R; Michael Serrato, M

2006-03-01

The SRS Ecology Environmental Information Document (EEID) provides a source of information on the ecology of Savannah River Site (SRS). The SRS is a U.S. Department of Energy (DOE)--owned property on the upper Atlantic Coastal Plain of South Carolina, centered approximately 40 kilometers (25 miles) southeast of Augusta, Georgia. The entire site was designated a National Environmental Research Park in 1972 by the Atomic Energy Commission, the predecessor of DOE. This document summarizes and synthesizes ecological research and monitoring conducted on the three main types of ecosystems found at SRS: terrestrial, wetland and aquatic. It also summarizes the available information on the threatened and endangered species found on the Savannah River Site. SRS is located along the Savannah River and encompasses an area of 80,267 hectares (310 square miles) in three South Carolina counties. It contains diverse habitats, flora, and fauna. Habitats include upland terrestrial areas, wetlands, streams, reservoirs, and the adjacent Savannah River. These diverse habitats support a variety of plants and animals, including many commercially or recreationally valuable species and several rare, threatened, or endangered species. Soils are the basic terrestrial resource, influencing the development of terrestrial biological communities. Many different soils exist on the SRS, from hydric to well-drained, and from sand to clay. In general, SRS soils are predominantly well-drained loamy sands.

Experiences with Use of Various Pedagogical Methods Utilizing a Student Response System -- Motivation and Learning Outcome

Science.gov (United States)

Arnesen, Ketil; Korpas, Guri Sivertsen; Hennissen, Jon Eirik; Stav, John Birger

2013-01-01

This paper describes use of an online Student Response System (SRS) in a pre-qualification course for engineering studies in Norway. The SRS in use, where students answer quizzes using handheld mobile devices like Smartphones, PADs, iPods etc., has been developed at Sor-Trondelag University College. The development of the SRS was co-funded by the …

Roadmap to the SRS computing architecture

Energy Technology Data Exchange (ETDEWEB)

Johnson, A.

1994-07-05

This document outlines the major steps that must be taken by the Savannah River Site (SRS) to migrate the SRS information technology (IT) environment to the new architecture described in the Savannah River Site Computing Architecture. This document proposes an IT environment that is {open_quotes}...standards-based, data-driven, and workstation-oriented, with larger systems being utilized for the delivery of needed information to users in a client-server relationship.{close_quotes} Achieving this vision will require many substantial changes in the computing applications, systems, and supporting infrastructure at the site. This document consists of a set of roadmaps which provide explanations of the necessary changes for IT at the site and describes the milestones that must be completed to finish the migration.

User guide to the SRS data logging facility

International Nuclear Information System (INIS)

Tyson, B.E.

1979-02-01

The state of the SRS is recorded every two minutes, thus providing a detailed History of its parameters. Recording of History is done via the SRS Computer Network. This consists of a Master Computer, an Interdata 7/32, and three Minicomputers, Interdata 7/16s. Each of the Minicomputers controls one of the accelerators, Linac, Booster and Storage Ring. The Master Computer is connected to the Central Computer, an IBM 370/165, for jobs where greater computing power and storage are required. The Master Computer has a total of 20 Megabytes of fixed and movable disc space but only about 5 Megabytes are available for History storage. The Minicomputers have no storage facilities. The user guide is set out as follows: History filing system, History storage on the Master Computer, transfer of the History to the Central Computer, transferring History to tapes, job integrity, the SRS tape catalogue system. (author)

Surveillance Analysis Computer System (SACS): Software requirements specification (SRS). Revision 2

International Nuclear Information System (INIS)

Glasscock, J.A.

1995-01-01

This document is the primary document establishing requirements for the Surveillance Analysis Computer System (SACS) database, an Impact Level 3Q system. SACS stores information on tank temperatures, surface levels, and interstitial liquid levels. This information is retrieved by the customer through a PC-based interface and is then available to a number of other software tools. The software requirements specification (SRS) describes the system requirements for the SACS Project, and follows the Standard Engineering Practices (WHC-CM-6-1), Software Practices (WHC-CM-3-10) and Quality Assurance (WHC-CM-4-2, QR 19.0) policies

Proceedings of the international conference on vacuum science and technology and SRS vacuum systems. V.1: accelerators and SRS systems

International Nuclear Information System (INIS)

Venkatramani, N.; Sinha, A.K.

1995-01-01

An International Conference on Vacuum Science and Technology, INCOVAST-95 was held during January 30 - February 2, 1995 at the Centre for Advanced Technology (CAT), Indore under the aegis of the Indian Vacuum Society. Centre for Advanced Technology has a major programme of design and construction of a 450 MeV electron storage ring, synchrotron radiation source Indus-1 followed by the 1.25 GeV Indus-2. To match the activities at the centre, the present conference had ultrahigh vacuum for Synchrotron Radiation Sources (SRSs) as the main theme. Three major topics, namely accelerators and SRS systems, thin films and surfaces, vacuum components and applications were covered in detail. A short summary of the discussions is also included in the proceedings. Papers relevant to INIS are indexed separately

Towards frameless maskless SRS through real-time 6DoF robotic motion compensation.

Science.gov (United States)

Belcher, Andrew H; Liu, Xinmin; Chmura, Steven; Yenice, Kamil; Wiersma, Rodney D

2017-11-13

Stereotactic radiosurgery (SRS) uses precise dose placement to treat conditions of the CNS. Frame-based SRS uses a metal head ring fixed to the patient's skull to provide high treatment accuracy, but patient comfort and clinical workflow may suffer. Frameless SRS, while potentially more convenient, may increase uncertainty of treatment accuracy and be physiologically confining to some patients. By incorporating highly precise robotics and advanced software algorithms into frameless treatments, we present a novel frameless and maskless SRS system where a robot provides real-time 6DoF head motion stabilization allowing positional accuracies to match or exceed those of traditional frame-based SRS. A 6DoF parallel kinematics robot was developed and integrated with a real-time infrared camera in a closed loop configuration. A novel compensation algorithm was developed based on an iterative closest-path correction approach. The robotic SRS system was tested on six volunteers, whose motion was monitored and compensated for in real-time over 15 min simulated treatments. The system's effectiveness in maintaining the target's 6DoF position within preset thresholds was determined by comparing volunteer head motion with and without compensation. Comparing corrected and uncorrected motion, the 6DoF robotic system showed an overall improvement factor of 21 in terms of maintaining target position within 0.5 mm and 0.5 degree thresholds. Although the system's effectiveness varied among the volunteers examined, for all volunteers tested the target position remained within the preset tolerances 99.0% of the time when robotic stabilization was used, compared to 4.7% without robotic stabilization. The pre-clinical robotic SRS compensation system was found to be effective at responding to sub-millimeter and sub-degree cranial motions for all volunteers examined. The system's success with volunteers has demonstrated its capability for implementation with frameless and maskless SRS

TH-C-BRC-01: An Overview of Emerging Technologies in SRS/SBRT Delivery

International Nuclear Information System (INIS)

Ma, L.

2016-01-01

The delivery techniques for SRS/SBRT have been under rapid developments in recent years, which pose new challenges to medical physicists ranging from planning and quality assurance to imaging and motion management. This educational course will provide a general overview of the latest delivery techniques in SRS/SBRT, and discuss the clinical processes to address the challenges of each technique with special emphasis on dedicated gamma-ray based device, robotic x-band linac-based system and conventional C-arm s-band linac-based SRS systems. (1). Gamma-ray based SRS/SRT: This is the gold standard of intracranial SRS. With the advent of precision imaging guidance and frameless patient positioning capabilities, novel stereoscopic CBCT and automatic dose adaption solution are introduced to the Gamma-ray based SRS for the first time. The first North American system has been approved by the US regulatory for patient treatments in the spring of 2016. (2). Robotic SRS/SBRT system: A number of technological milestones have been developed in the past few years, including variable aperture collimator, sequential optimization technique, and the time reduction technique. Recently, a new robotic model allows the option of a multi-leaf collimator. These technological advances have reduced the treatment time and improved dose conformity significantly and could potentially expand the application of radiosurgery for the treatment of targets not previously suitable for robotic SRS/SBRT or fractionated stereotactic radiotherapy. These technological advances have created new demanding mandates on hardware and patient quality assurance (QA) tasks, as well as the need for updating/educating the physicists in the community on these requirements. (3). Conventional Linac based treatments: Modulated arc therapy (MAT) has gained wide popularities in Linac-based treatments in recent years due to its high delivery efficiency and excellent dose conformities. Recently, MAT has been introduced to

TH-C-BRC-01: An Overview of Emerging Technologies in SRS/SBRT Delivery

Energy Technology Data Exchange (ETDEWEB)

Ma, L. [UCSF Comprehensive Cancer Center, San Francisco, CA (United States)

2016-06-15

The delivery techniques for SRS/SBRT have been under rapid developments in recent years, which pose new challenges to medical physicists ranging from planning and quality assurance to imaging and motion management. This educational course will provide a general overview of the latest delivery techniques in SRS/SBRT, and discuss the clinical processes to address the challenges of each technique with special emphasis on dedicated gamma-ray based device, robotic x-band linac-based system and conventional C-arm s-band linac-based SRS systems. (1). Gamma-ray based SRS/SRT: This is the gold standard of intracranial SRS. With the advent of precision imaging guidance and frameless patient positioning capabilities, novel stereoscopic CBCT and automatic dose adaption solution are introduced to the Gamma-ray based SRS for the first time. The first North American system has been approved by the US regulatory for patient treatments in the spring of 2016. (2). Robotic SRS/SBRT system: A number of technological milestones have been developed in the past few years, including variable aperture collimator, sequential optimization technique, and the time reduction technique. Recently, a new robotic model allows the option of a multi-leaf collimator. These technological advances have reduced the treatment time and improved dose conformity significantly and could potentially expand the application of radiosurgery for the treatment of targets not previously suitable for robotic SRS/SBRT or fractionated stereotactic radiotherapy. These technological advances have created new demanding mandates on hardware and patient quality assurance (QA) tasks, as well as the need for updating/educating the physicists in the community on these requirements. (3). Conventional Linac based treatments: Modulated arc therapy (MAT) has gained wide popularities in Linac-based treatments in recent years due to its high delivery efficiency and excellent dose conformities. Recently, MAT has been introduced to

Repeat Courses of Stereotactic Radiosurgery (SRS), Deferring Whole-Brain Irradiation, for New Brain Metastases After Initial SRS

Energy Technology Data Exchange (ETDEWEB)

Shultz, David B.; Modlin, Leslie A.; Jayachandran, Priya; Von Eyben, Rie; Gibbs, Iris C. [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California (United States); Choi, Clara Y.H. [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California (United States); Department of Radiation Oncology, Santa Clara Valley Medical Center, San Jose, California (United States); Chang, Steven D.; Harsh, Griffith R.; Li, Gordon; Adler, John R. [Department of Neurosurgery, Stanford University School of Medicine, Stanford, California (United States); Hancock, Steven L. [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California (United States); Soltys, Scott G., E-mail: sgsoltys@stanford.edu [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California (United States)

2015-08-01

Purpose: To report the outcomes of repeat stereotactic radiosurgery (SRS), deferring whole-brain radiation therapy (WBRT), for distant intracranial recurrences and identify factors associated with prolonged overall survival (OS). Patients and Methods: We retrospectively identified 652 metastases in 95 patients treated with 2 or more courses of SRS for brain metastases, deferring WBRT. Cox regression analyzed factors predictive for OS. Results: Patients had a median of 2 metastases (range, 1-14) treated per course, with a median of 2 courses (range, 2-14) of SRS per patient. With a median follow-up after first SRS of 15 months (range, 3-98 months), the median OS from the time of the first and second course of SRS was 18 (95% confidence interval [CI] 15-24) and 11 months (95% CI 6-17), respectively. On multivariate analysis, histology, graded prognostic assessment score, aggregate tumor volume (but not number of metastases), and performance status correlated with OS. The 1-year cumulative incidence, with death as a competing risk, of local failure was 5% (95% CI 4-8%). Eighteen (24%) of 75 deaths were from neurologic causes. Nineteen patients (20%) eventually received WBRT. Adverse radiation events developed in 2% of SRS sites. Conclusion: Multiple courses of SRS, deferring WBRT, for distant brain metastases after initial SRS, seem to be a safe and effective approach. The graded prognostic assessment score, updated at each course, and aggregate tumor volume may help select patients in whom the deferral of WBRT might be most beneficial.

Comparison of Srs-24 And Srs-22 Scores in Thirty Eight Adolescent Idiopathic Scoliosis Patients Who Had Undergone Surgical Correction

Directory of Open Access Journals (Sweden)

CYW Chan

2009-05-01

Full Text Available Adolescent idiopathic scoliosis is a spinal deformity that affects patients’ self image and confidence. Surgery is offered when the curvature is greater than 50 degrees based on the likelihood of curvature progression. Outcome measures for scoliosis correction can be described in terms of radiological improvement or improvement of health related quality of life scores. The Scoliosis Research Society 22 (SRS-22 and Scoliosis Research Society 24 (SRS-24 questionnaires are widely accepted and used to characterize clinical results. Therefore, this prospective study of 38 patients aims to investigate how the SRS-24 and SRS-22 questionnaires compare to each other in terms of scoring when the same group of patients is evaluated. The SRS-22 questionnaire tends to give an inflated value in the overall score, pain and self image domain compared to the SRS-24 questionnaire.

Towards frameless maskless SRS through real-time 6DoF robotic motion compensation

Science.gov (United States)

Belcher, Andrew H.; Liu, Xinmin; Chmura, Steven; Yenice, Kamil; Wiersma, Rodney D.

2017-12-01

Stereotactic radiosurgery (SRS) uses precise dose placement to treat conditions of the CNS. Frame-based SRS uses a metal head ring fixed to the patient’s skull to provide high treatment accuracy, but patient comfort and clinical workflow may suffer. Frameless SRS, while potentially more convenient, may increase uncertainty of treatment accuracy and be physiologically confining to some patients. By incorporating highly precise robotics and advanced software algorithms into frameless treatments, we present a novel frameless and maskless SRS system where a robot provides real-time 6DoF head motion stabilization allowing positional accuracies to match or exceed those of traditional frame-based SRS. A 6DoF parallel kinematics robot was developed and integrated with a real-time infrared camera in a closed loop configuration. A novel compensation algorithm was developed based on an iterative closest-path correction approach. The robotic SRS system was tested on six volunteers, whose motion was monitored and compensated for in real-time over 15 min simulated treatments. The system’s effectiveness in maintaining the target’s 6DoF position within preset thresholds was determined by comparing volunteer head motion with and without compensation. Comparing corrected and uncorrected motion, the 6DoF robotic system showed an overall improvement factor of 21 in terms of maintaining target position within 0.5 mm and 0.5 degree thresholds. Although the system’s effectiveness varied among the volunteers examined, for all volunteers tested the target position remained within the preset tolerances 99.0% of the time when robotic stabilization was used, compared to 4.7% without robotic stabilization. The pre-clinical robotic SRS compensation system was found to be effective at responding to sub-millimeter and sub-degree cranial motions for all volunteers examined. The system’s success with volunteers has demonstrated its capability for implementation with frameless and

SU-F-T-576: Characterization of Two Dimensional Liquid Filled Detector Array(SRS 1000) in High Precision Cyberknife Robotic Radiosurgery System

International Nuclear Information System (INIS)

Muthukumaran, M; Manigandan, D; Murali, V; Chitra, S; Ganapathy, K; Vikraman, S

2016-01-01

Purpose: The aim of the study is to characterize a two dimensional liquid filled detector array SRS 1000 for routine QA in Cyberknife Robotic Radiosurgery system. Methods: SRS 1000 consists of 977 liquid filled ionization chambers and is designed to be used in small field SRS/SBRT techniques. The detector array has got two different spacial resolutions. Till field size of 5.5×5.5 cm the spacial resolution is 2.5mm (center to center) and after that till field size of 11 × 11 cm the spacial resolution is 5mm. The size of the detector is 2.3 × 2.3 0.5 mm with a volume of .003 cc. The CyberKnife Robotic Radiosurgery System is a frameless stereotactic radiosurgery system in which a LINAC is mounted on a robotic manipulator to deliver beams with a high sub millimeter accuracy. The SRS 1000’s MU linearity, stability, reproducibility in Cyberknife Robotic Radiosurgery system was measured and investigated. The output factors for fixed and IRIS collimators for all available collimators (5mm till 60 mm) was measured and compared with the measurement done with PTW pin-point ionization chamber. Results: The MU linearity was measured from 2 MU till 1000 MU for doserates in the range of 700cGy/min – 780 cGy/min and compared with the measurement done with pin point chamber The MU linearity was with in 3%. The detector arrays stability and reproducibility was excellent and was withinin 0.5% The measured output factors showed an agreement of better than 2% when compared with the measurements with pinpoint chamber for both fixed and IRIS collimators with all available field sizes. Conclusion: We have characterised PTW 1000 SRS as a precise and accurate measurement tool for routine QA of Cyberknife Robotic radiosurgery system.

SU-F-T-576: Characterization of Two Dimensional Liquid Filled Detector Array(SRS 1000) in High Precision Cyberknife Robotic Radiosurgery System

Energy Technology Data Exchange (ETDEWEB)

Muthukumaran, M [Apollo Speciality Hospitals, Chennai, Tamil Nadu (India); Manigandan, D [Fortis Cancer Institute, Mohali, Punjab (India); Murali, V; Chitra, S; Ganapathy, K [Apollo Speciality Hospital, Chennai, Tamil Nadu (India); Vikraman, S [Jaypee Hospital – Radiation Onology, Noida, UTTAR PRADESH (India)

2016-06-15

Purpose: The aim of the study is to characterize a two dimensional liquid filled detector array SRS 1000 for routine QA in Cyberknife Robotic Radiosurgery system. Methods: SRS 1000 consists of 977 liquid filled ionization chambers and is designed to be used in small field SRS/SBRT techniques. The detector array has got two different spacial resolutions. Till field size of 5.5×5.5 cm the spacial resolution is 2.5mm (center to center) and after that till field size of 11 × 11 cm the spacial resolution is 5mm. The size of the detector is 2.3 × 2.3 0.5 mm with a volume of .003 cc. The CyberKnife Robotic Radiosurgery System is a frameless stereotactic radiosurgery system in which a LINAC is mounted on a robotic manipulator to deliver beams with a high sub millimeter accuracy. The SRS 1000’s MU linearity, stability, reproducibility in Cyberknife Robotic Radiosurgery system was measured and investigated. The output factors for fixed and IRIS collimators for all available collimators (5mm till 60 mm) was measured and compared with the measurement done with PTW pin-point ionization chamber. Results: The MU linearity was measured from 2 MU till 1000 MU for doserates in the range of 700cGy/min – 780 cGy/min and compared with the measurement done with pin point chamber The MU linearity was with in 3%. The detector arrays stability and reproducibility was excellent and was withinin 0.5% The measured output factors showed an agreement of better than 2% when compared with the measurements with pinpoint chamber for both fixed and IRIS collimators with all available field sizes. Conclusion: We have characterised PTW 1000 SRS as a precise and accurate measurement tool for routine QA of Cyberknife Robotic radiosurgery system.

Upgrade of the TOTEM DAQ using the Scalable Readout System (SRS)

International Nuclear Information System (INIS)

Quinto, M; Cafagna, F; Fiergolski, A; Radicioni, E

2013-01-01

The main goals of the TOTEM Experiment at the LHC are the measurements of the elastic and total p-p cross sections and the studies of the diffractive dissociation processes. At LHC, collisions are produced at a rate of 40 MHz, imposing strong requirements for the Data Acquisition Systems (DAQ) in terms of trigger rate and data throughput. The TOTEM DAQ adopts a modular approach that, in standalone mode, is based on VME bus system. The VME based Front End Driver (FED) modules, host mezzanines that receive data through optical fibres directly from the detectors. After data checks and formatting are applied in the mezzanine, data is retransmitted to the VME interface and to another mezzanine card plugged in the FED module. The VME bus maximum bandwidth limits the maximum first level trigger (L1A) to 1 kHz rate. In order to get rid of the VME bottleneck and improve scalability and the overall capabilities of the DAQ, a new system was designed and constructed based on the Scalable Readout System (SRS), developed in the framework of the RD51 Collaboration. The project aims to increase the efficiency of the actual readout system providing higher bandwidth, and increasing data filtering, implementing a second-level trigger event selection based on hardware pattern recognition algorithms. This goal is to be achieved preserving the maximum back compatibility with the LHC Timing, Trigger and Control (TTC) system as well as with the CMS DAQ. The obtained results and the perspectives of the project are reported. In particular, we describe the system architecture and the new Opto-FEC adapter card developed to connect the SRS with the FED mezzanine modules. A first test bench was built and validated during the last TOTEM data taking period (February 2013). Readout of a set of 3 TOTEM Roman Pot silicon detectors was carried out to verify performance in the real LHC environment. In addition, the test allowed a check of data consistency and quality

TH-C-BRC-03: Emerging Linac Based SRS/SBRT Technologies with Modulated Arc Delivery

International Nuclear Information System (INIS)

Ren, L.

2016-01-01

The delivery techniques for SRS/SBRT have been under rapid developments in recent years, which pose new challenges to medical physicists ranging from planning and quality assurance to imaging and motion management. This educational course will provide a general overview of the latest delivery techniques in SRS/SBRT, and discuss the clinical processes to address the challenges of each technique with special emphasis on dedicated gamma-ray based device, robotic x-band linac-based system and conventional C-arm s-band linac-based SRS systems. (1). Gamma-ray based SRS/SRT: This is the gold standard of intracranial SRS. With the advent of precision imaging guidance and frameless patient positioning capabilities, novel stereoscopic CBCT and automatic dose adaption solution are introduced to the Gamma-ray based SRS for the first time. The first North American system has been approved by the US regulatory for patient treatments in the spring of 2016. (2). Robotic SRS/SBRT system: A number of technological milestones have been developed in the past few years, including variable aperture collimator, sequential optimization technique, and the time reduction technique. Recently, a new robotic model allows the option of a multi-leaf collimator. These technological advances have reduced the treatment time and improved dose conformity significantly and could potentially expand the application of radiosurgery for the treatment of targets not previously suitable for robotic SRS/SBRT or fractionated stereotactic radiotherapy. These technological advances have created new demanding mandates on hardware and patient quality assurance (QA) tasks, as well as the need for updating/educating the physicists in the community on these requirements. (3). Conventional Linac based treatments: Modulated arc therapy (MAT) has gained wide popularities in Linac-based treatments in recent years due to its high delivery efficiency and excellent dose conformities. Recently, MAT has been introduced to

TH-C-BRC-02: A Review of Emerging Technologies in Robotic SRS/SBRT Delivery

Energy Technology Data Exchange (ETDEWEB)

Wang, L. [Stanford University Cancer Center (United States)

2016-06-15

The delivery techniques for SRS/SBRT have been under rapid developments in recent years, which pose new challenges to medical physicists ranging from planning and quality assurance to imaging and motion management. This educational course will provide a general overview of the latest delivery techniques in SRS/SBRT, and discuss the clinical processes to address the challenges of each technique with special emphasis on dedicated gamma-ray based device, robotic x-band linac-based system and conventional C-arm s-band linac-based SRS systems. (1). Gamma-ray based SRS/SRT: This is the gold standard of intracranial SRS. With the advent of precision imaging guidance and frameless patient positioning capabilities, novel stereoscopic CBCT and automatic dose adaption solution are introduced to the Gamma-ray based SRS for the first time. The first North American system has been approved by the US regulatory for patient treatments in the spring of 2016. (2). Robotic SRS/SBRT system: A number of technological milestones have been developed in the past few years, including variable aperture collimator, sequential optimization technique, and the time reduction technique. Recently, a new robotic model allows the option of a multi-leaf collimator. These technological advances have reduced the treatment time and improved dose conformity significantly and could potentially expand the application of radiosurgery for the treatment of targets not previously suitable for robotic SRS/SBRT or fractionated stereotactic radiotherapy. These technological advances have created new demanding mandates on hardware and patient quality assurance (QA) tasks, as well as the need for updating/educating the physicists in the community on these requirements. (3). Conventional Linac based treatments: Modulated arc therapy (MAT) has gained wide popularities in Linac-based treatments in recent years due to its high delivery efficiency and excellent dose conformities. Recently, MAT has been introduced to

TH-C-BRC-03: Emerging Linac Based SRS/SBRT Technologies with Modulated Arc Delivery

Energy Technology Data Exchange (ETDEWEB)

Ren, L. [Duke University Medical Center (United States)

2016-06-15

The delivery techniques for SRS/SBRT have been under rapid developments in recent years, which pose new challenges to medical physicists ranging from planning and quality assurance to imaging and motion management. This educational course will provide a general overview of the latest delivery techniques in SRS/SBRT, and discuss the clinical processes to address the challenges of each technique with special emphasis on dedicated gamma-ray based device, robotic x-band linac-based system and conventional C-arm s-band linac-based SRS systems. (1). Gamma-ray based SRS/SRT: This is the gold standard of intracranial SRS. With the advent of precision imaging guidance and frameless patient positioning capabilities, novel stereoscopic CBCT and automatic dose adaption solution are introduced to the Gamma-ray based SRS for the first time. The first North American system has been approved by the US regulatory for patient treatments in the spring of 2016. (2). Robotic SRS/SBRT system: A number of technological milestones have been developed in the past few years, including variable aperture collimator, sequential optimization technique, and the time reduction technique. Recently, a new robotic model allows the option of a multi-leaf collimator. These technological advances have reduced the treatment time and improved dose conformity significantly and could potentially expand the application of radiosurgery for the treatment of targets not previously suitable for robotic SRS/SBRT or fractionated stereotactic radiotherapy. These technological advances have created new demanding mandates on hardware and patient quality assurance (QA) tasks, as well as the need for updating/educating the physicists in the community on these requirements. (3). Conventional Linac based treatments: Modulated arc therapy (MAT) has gained wide popularities in Linac-based treatments in recent years due to its high delivery efficiency and excellent dose conformities. Recently, MAT has been introduced to

TH-C-BRC-02: A Review of Emerging Technologies in Robotic SRS/SBRT Delivery

International Nuclear Information System (INIS)

Wang, L.

2016-01-01

The delivery techniques for SRS/SBRT have been under rapid developments in recent years, which pose new challenges to medical physicists ranging from planning and quality assurance to imaging and motion management. This educational course will provide a general overview of the latest delivery techniques in SRS/SBRT, and discuss the clinical processes to address the challenges of each technique with special emphasis on dedicated gamma-ray based device, robotic x-band linac-based system and conventional C-arm s-band linac-based SRS systems. (1). Gamma-ray based SRS/SRT: This is the gold standard of intracranial SRS. With the advent of precision imaging guidance and frameless patient positioning capabilities, novel stereoscopic CBCT and automatic dose adaption solution are introduced to the Gamma-ray based SRS for the first time. The first North American system has been approved by the US regulatory for patient treatments in the spring of 2016. (2). Robotic SRS/SBRT system: A number of technological milestones have been developed in the past few years, including variable aperture collimator, sequential optimization technique, and the time reduction technique. Recently, a new robotic model allows the option of a multi-leaf collimator. These technological advances have reduced the treatment time and improved dose conformity significantly and could potentially expand the application of radiosurgery for the treatment of targets not previously suitable for robotic SRS/SBRT or fractionated stereotactic radiotherapy. These technological advances have created new demanding mandates on hardware and patient quality assurance (QA) tasks, as well as the need for updating/educating the physicists in the community on these requirements. (3). Conventional Linac based treatments: Modulated arc therapy (MAT) has gained wide popularities in Linac-based treatments in recent years due to its high delivery efficiency and excellent dose conformities. Recently, MAT has been introduced to

Questionário SRS-30 para adolescentes portadores de escoliose idiopática Cuestionario SRS-30 para adolescentes portadores de escoliosis idiopática SRS-30 Questionnaire for adolescents with idiophatic scoliosis

Directory of Open Access Journals (Sweden)

Gustavo Carriço de Oliveira

2010-06-01

Full Text Available INTRODUÇÃO: a medição da qualidade de vida relacionada à saúde é uma prática comum na avaliação de doenças da coluna vertebral. O questionário SRS-30 (versão procedente do instrumento Scoliosis Research Society-22 é um instrumento válido para a avaliação clínica de pacientes portadores de escoliose idiopática nos Estados Unidos. Entretanto, sua adaptação em outros idiomas é necessária para uso multinacional. OBJETIVO: analisar os domínios e itens do questionário SRS-30 para adolescentes. Discutir a aplicação do questionário da Scoliosis Research Society (SRS em diversas versões. DESENHO DE ESTUDO: revisão narrativa da literatura sobre um questionário para mensurar a qualidade de vida relacionada à saúde e suas versões em diferentes idiomas. MÉTODOS: Foi conduzida uma revisão narrativa da literatura em relação à tradução e validação dos questionários SRS-22, SRS-24 e SRS-30. RESULTADOS: oito publicações descrevendo a tradução e validação do questionário SRS nos idiomas espanhol, japonês, turco, chinês, italiano e alemão foram identificadas na literatura. Nenhum artigo sobre o questionário SRS-30 na versão brasileira foi localizado na literatura. O conteúdo dos itens de cada domínio se refere tanto a dados concretos e fáceis de precisar como também às experiências subjetivas das pessoas e às reações emocionais diante de determinados fatos. A maioria dos instrumentos que avaliam qualidade de vida foi desenvolvida no idioma inglês e existe a necessidade da adaptação destes questionários para o uso em países cuja língua oficial não seja o inglês. CONCLUSÕES: questionários que avaliam qualidade de vida relacionada à saúde devem sofrer adaptações culturais para manter a validade interna do instrumento. Para isso, urge outro desenho de estudo para a validação do questionário SRS-30 em português brasileiro para que se determine sua validade em comparação aos question

Test Review: Constantino, J. N., & Gruber, C. P. (2012). "Social Responsiveness Scale-Second Edition" ("SRS-2"). Torrance, CA: Western Psychological Services

Science.gov (United States)

Bruni, Teryn P.

2014-01-01

This article reviews the Social Responsiveness Scale-Second Edition (SRS-2), a 65-item rating scale measuring deficits in social behavior associated with Autism Spectrum Disorder (ASD), as outlined by the "Diagnostic and Statistical Manual of Mental Disorders" (4th ed., text rev.; "DSM-IV-TR"; American Psychiatric Association,…

RADIOLYTIC HYDROGEN GENERATION INSAVANNAH RIVER SITE (SRS) HIGH LEVEL WASTETANKS COMPARISON OF SRS AND HANFORDMODELING PREDICTIONS

Energy Technology Data Exchange (ETDEWEB)

Crawford, C; Ned Bibler, N

2009-04-15

In the high level waste tanks at the Savannah River Site (SRS), hydrogen is produced continuously by interaction of the radiation in the tank with water in the waste. Consequently, the vapor spaces of the tanks are purged to prevent the accumulation of H{sub 2} and possible formation of a flammable mixture in a tank. Personnel at SRS have developed an empirical model to predict the rate of H{sub 2} formation in a tank. The basis of this model is the prediction of the G value for H{sub 2} production. This G value is the number of H{sub 2} molecules produced per 100 eV of radiolytic energy absorbed by the waste. Based on experimental studies it was found that the G value for H{sub 2} production from beta radiation and from gamma radiation were essentially equal. The G value for H{sub 2} production from alpha radiation was somewhat higher. Thus, the model has two equations, one for beta/gamma radiation and one for alpha radiation. Experimental studies have also indicated that both G values are decreased by the presence of nitrate and nitrite ions in the waste. These are the main scavengers for the precursors of H{sub 2} in the waste; thus the equations that were developed predict G values for hydrogen production as a function of the concentrations of these two ions in waste. Knowing the beta/gamma and alpha heat loads in the waste allows one to predict the total generation rate for hydrogen in a tank. With this prediction a ventilation rate can be established for each tank to ensure that a flammable mixture is not formed in the vapor space in a tank. Recently personnel at Hanford have developed a slightly different model for predicting hydrogen G values. Their model includes the same precursor for H{sub 2} as the SRS model but also includes an additional precursor not in the SRS model. Including the second precursor for H{sub 2} leads to different empirical equations for predicting the G values for H{sub 2} as a function of the nitrate and nitrite concentrations in

Pump spectral linewidth influence on stimulated Brillouin scattering (SBS) and stimulated Raman scattering (SRS) and self-termination behavior of SRS in liquids

Energy Technology Data Exchange (ETDEWEB)

He, Guang S.; Kuzmin, Andrey; Prasad, Paras N. [The Institute for Lasers, Photonics and Biophotonics, State University of New York, Buffalo, NY (United States)

2016-12-15

The threshold, temporal behavior, and conversion efficiency of stimulated Brillouin scattering (SBS) and stimulated Raman scattering (SBS) in three liquids (benzene, hexane, and dimethyl sulfoxide) and two crystals (calcite and barium nitrate) have been investigated under three largely different spectral linewidth conditions. Pumped with 532-nm and nanosecond duration laser pulses of ≤ 0.01 cm{sup -1} linewidth, only SBS can be generated in all tested liquids with a high nonlinear reflectivity. However when the pump spectral linewidth is ∝0.07 cm{sup -1} or ∝0.8 cm{sup -1}, both SBS and SRS can be observed in benzene while only SRS can be generated in dimethyl sulfoxide; in all these cases SRS is the dominant contribution to the stimulated scattering but the efficiency values are drastically decreased due to the self-termination behavior of SRS in liquids, which arises from the thermal self-defocusing of both pump beam and SRS beam owing to Stokes-shift related opto-heating effect. In contrast, for SRS process in the two crystals, the thermal self-defocusing influence is negligible benefitting from their much greater thermal conductivity, and a higher conversion efficiency of SRS generation can be retained under all three pump conditions. (copyright 2016 by WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

Improving the measurement of health-related quality of life in adolescent with idiopathic scoliosis: the SRS-7, a Rasch-developed short form of the SRS-22 questionnaire.

Science.gov (United States)

Caronni, Antonio; Zaina, Fabio; Negrini, Stefano

2014-04-01

Scoliosis Research Society-22 (SRS-22) questionnaire was developed to evaluate health-related quality of life (HRQL) in adolescent idiopathic scoliosis (AIS) patients. Rasch analysis (RA) is a statistical procedure which turns questionnaire ordinal scores into interval measures. Measures from Rasch-compatible questionnaires can be used, similar to body temperature or blood pressure, to quantify disease severity progression and treatment efficacy. Purpose of the current work is to present Rasch analysis (RA) of the SRS-22 questionnaire and to develop an SRS-22 Rasch-approved short form. 300 SRS-22 were randomly collected from 2447 consecutive IS adolescents at their first evaluation (229 females; 13.9 ± 1.9 years; 26.9 ± 14.7 Cobb°) in a scoliosis outpatient clinic. RA showed both disordered thresholds and overall misfit of the SRS-22. Sixteen items were re-scored and two misfitting items (6 and 14) removed to obtain a Rasch-compatible questionnaire. Participants HRQL measured too high with the rearranged questionnaire, indicating a severe SRS-22 ceiling effect. RA also highlighted SRS-22 multidimensionality, with pain/function not merging with self-image/mental health items. Item 3 showed differential item functioning (DIF) for both curve and hump amplitude. A 7-item questionnaire (SRS-7) was prepared by selecting single items from the original SRS-22. SRS-7 showed fit to the model, unidimensionality and no DIF. Compared with the SRS-22, the short form scale shows better targeting of the participants' population. RA shows that SRS-22 has poor clinimetric properties; moreover, when used with AIS at first evaluation, SRS-22 is affected by a severe ceiling effect. SRS-7, an SRS-22 7-item short form questionnaire, provides an HRQL interval measure better tailored to these participants. Copyright © 2014 Elsevier Ltd. All rights reserved.

Reliability and validity of adapted French Canadian version of Scoliosis Research Society Outcomes Questionnaire (SRS-22) in Quebec.

Science.gov (United States)

Beauséjour, Marie; Joncas, Julie; Goulet, Lise; Roy-Beaudry, Marjolaine; Parent, Stefan; Grimard, Guy; Forcier, Martin; Lauriault, Sophie; Labelle, Hubert

2009-03-15

Prospective validation study of a cross-cultural adaptation of the Scoliosis Research Society (SRS) Outcomes Questionnaire. To provide a French Canadian version of the SRS Outcomes Questionnaire and to empirically test its response in healthy adolescents and adolescent idiopathic scoliosis (AIS) patients in Québec. The SRS Outcomes Questionnaire is widely used for the assessment of health-related quality of life in AIS patients. French translation and back-translation of the SRS-22 (SRS-22-fv) were done by an expert committee. Its reliability was measured using the coefficient of internal consistency, construct validity with a factorial analysis, concurrent validity by using the short form-12 and discriminant validity using ANOVA and multivariate linear regression, on 145 AIS patients, 44 patients with non clinically significant scoliosis (NCSS), and 64 healthy patients. The SRS-22-fv showed a good global internal consistency (AIS: Cronbach alpha = 0.86, NCSS: 0.81, and controls: 0.79) and in all of its domains for AIS patients. The factorial structure was coherent with the original questionnaire (47.4% of explained variance). High correlation coefficients were obtained between SRS-22-fv and short form-12 corresponding domains. Boys had higher scores than girls, scores worsened with age, and with increasing body mass index. Mean Total, Pain, Self-image, and Satisfaction scores, were correlated with Cobb angle. Adjusted regression models showed statistically significant differences between the AIS, NCSS, and control groups in the Total, Pain, and Function scores. The SRS-22-fv showed satisfactory reliability, factorial, concurrent, and discriminant validity. This study provides scores in a significant group of healthy adolescents and demonstrates a clear gradient in response between subjects with AIS, NCSS, and controls.

Comparison of stereotactic radiosurgery (SRS) alone and whole brain radiotherapy (WBRT) plus a stereotactic boost (WBRT + SRS) for one to three brain metastases

Energy Technology Data Exchange (ETDEWEB)

Rades, Dirk [University Hospital Schleswig-Holstein, Luebeck (Germany). Department of Radiation Oncology]|[University Medical Center, Hamburg (Germany). Department of Radiation Oncology; Kueter, Jan-Dirk; Dunst, Juergen [University Hospital Schleswig-Holstein, Luebeck (Germany). Department of Radiation Oncology; Hornung, Dagmar [University Medical Center, Hamburg (Germany). Department of Radiation Oncology; Veninga, Theo; Hanssens, Patrick [Dr. Bernard Verbeeten Institute, Tilburg (Netherlands). Department of Radiation Oncology; Schild, Steven E. [Mayo Clinic Scottsdale, AZ (United States). Department of Radiation Oncology

2008-12-15

The best available treatment of patients with one to three brain metastases is still unclear. This study compared the results of stereotactic radiosurgery (SRS) alone and whole brain radiotherapy (WBRT) plus SRS (WBRT + SRS). Survival (OS), intracerebral control (IC), and local control of treated metastases (LC) were retrospectively analyzed in 144 patients receiving SRS alone (n = 93) or WBRT + SRS (n = 51). Eight additional potential prognostic factors were evaluated: age, gender, Eastern Cooperative Oncology Group performance score (ECOG-PS), tumor type, number of brain metastases, extracerebral metastases, recursive partitioning analysis (RPA) class, and interval from tumor diagnosis to irradiation. Subgroup analyses were performed for RPA class I and II patients. 1-year-OS was 53% after SRS and 56% after WBRT + SRS (p = 0.24). 1-year-IC rates were 51% and 66% (p = 0.015), respectively. 1-year-LC rates were 66% and 87% (p = 0.003), respectively. On multivariate analyses, OS was associated with age (p = 0.004), ECOG-PS (p = 0.005), extracerebral metastases (p < 0.001), RPA class (p < 0.001), and interval from tumor diagnosis to irradiation (p < 0.001). IC was associated with interval from tumor diagnosis to irradiation (p = 0.004) and almost with treatment (p = 0.09), and LC with treatment (p = 0.026) and almost with interval (p = 0.08). The results of the subgroup analyses were similar to those of the entire cohort. The increase in IC was stronger in RPA class I patients. WBRT + SRS resulted in better IC and LC but not better OS than SRS alone. Because also IC and LC are important end-points, additional WBRT appears justified in patients with one to three brain metastases, in particular in RPA class I patients. (orig.)

Comparison of stereotactic radiosurgery (SRS) alone and whole brain radiotherapy (WBRT) plus a stereotactic boost (WBRT + SRS) for one to three brain metastases

International Nuclear Information System (INIS)

Rades, Dirk; University Medical Center, Hamburg; Kueter, Jan-Dirk; Dunst, Juergen; Hornung, Dagmar; Veninga, Theo; Hanssens, Patrick; Schild, Steven E.

2008-01-01

The best available treatment of patients with one to three brain metastases is still unclear. This study compared the results of stereotactic radiosurgery (SRS) alone and whole brain radiotherapy (WBRT) plus SRS (WBRT + SRS). Survival (OS), intracerebral control (IC), and local control of treated metastases (LC) were retrospectively analyzed in 144 patients receiving SRS alone (n = 93) or WBRT + SRS (n = 51). Eight additional potential prognostic factors were evaluated: age, gender, Eastern Cooperative Oncology Group performance score (ECOG-PS), tumor type, number of brain metastases, extracerebral metastases, recursive partitioning analysis (RPA) class, and interval from tumor diagnosis to irradiation. Subgroup analyses were performed for RPA class I and II patients. 1-year-OS was 53% after SRS and 56% after WBRT + SRS (p = 0.24). 1-year-IC rates were 51% and 66% (p = 0.015), respectively. 1-year-LC rates were 66% and 87% (p = 0.003), respectively. On multivariate analyses, OS was associated with age (p = 0.004), ECOG-PS (p = 0.005), extracerebral metastases (p < 0.001), RPA class (p < 0.001), and interval from tumor diagnosis to irradiation (p < 0.001). IC was associated with interval from tumor diagnosis to irradiation (p = 0.004) and almost with treatment (p = 0.09), and LC with treatment (p = 0.026) and almost with interval (p = 0.08). The results of the subgroup analyses were similar to those of the entire cohort. The increase in IC was stronger in RPA class I patients. WBRT + SRS resulted in better IC and LC but not better OS than SRS alone. Because also IC and LC are important end-points, additional WBRT appears justified in patients with one to three brain metastases, in particular in RPA class I patients. (orig.)

The Rush to Remediate: Long Term Performance Favors Passive Systems at SRS

International Nuclear Information System (INIS)

Hoffman, D.; Cauthen, K.; Beul, R. R.

2003-01-01

The purpose of this paper is to describe the long-term performance of groundwater remediation systems at SRS and compare active versus passive systems. The presentation will focus on the limited effectiveness of active pump and treat systems and share the experience with more passive and natural systems such as soil vapor extraction, barometric pumping, bioremediation, and phytoremediation. Three remediation projects are presented. In each case the waste source is capped with clay or synthetic barriers; however, extensive groundwater contamination remains. The first project features the cleanup of the largest plume in the United States. The second project entails solvent and vinyl chloride remediation of groundwater beneath a hazardous waste landfill. The third project discusses tritium containment from a 160-acre radioactive waste disposal area. Special emphasis is placed on performance data from alternate technology cleanup. The goals are to share remediation data, successes and lessons learned, while making a case for passive systems use in groundwater remediation

SU-F-T-638: Is There A Need For Immobilization in SRS?

International Nuclear Information System (INIS)

Masterova, K; Sethi, A; Anderson, D; Prabhu, V; Rusu, I; Gros, S; Melian, E

2016-01-01

Purpose: Frameless Stereotactic radiosurgery (SRS) is increasingly used in the clinic. Cone-Beam CT (CBCT) to simulation-CT match has replaced the 3-dimensional coordinate based set up using a stereotactic localizing frame. The SRS frame however served as both a localizing and immobilizing device. We seek to measure the quality of frameless (mask based) and frame based immobilization and evaluate its impact on target dose. Methods: Each SRS patient was set up by kV on-board imaging (OBI) and then fine-tuned with CBCT. A second CBCT was done at treatment-end to ascertain intrafraction motion. We compared pre- vs post-treatment CBCT shifts for both frameless and frame based SRS patients. CBCT to sim-CT fusion was repeated for each patient off-line to assess systematic residual image registration error. Each patient was re-planned with measured shifts to assess effects on target dose. Results: We analyzed 11 patients (12 lesions) treated with frameless SRS and 6 patients (11 lesions) with a fixed frame system. Average intra-fraction iso-center positioning errors for frameless and frame-based treatments were 1.24 ± 0.57 mm and 0.28 ± 0.08 mm (mean ± s.d.) respectively. Residual error in CBCT registration was 0.24 mm. The frameless positioning uncertainties led to target dose errors in Dmin and D95 of 15.5 ± 18.4% and 6.6 ± 9.1% respectively. The corresponding errors in fixed frame SRS were much lower with Dmin and D95 reduced by 4.2 ± 6.5% and D95 2.5 ± 3.8% respectively. Conclusion: Frameless mask provides good immobilization with average patient motion of 1.2 mm during treatment. This exceeds MRI voxel dimensions (∼0.43mm) used for target delineation. Frame-based SRS provides superior patient immobilization with measureable movement no greater than the background noise of the CBCT registration. Small lesions requiring submm precision are better served with a frame based SRS.

SU-F-T-638: Is There A Need For Immobilization in SRS?

Energy Technology Data Exchange (ETDEWEB)

Masterova, K; Sethi, A; Anderson, D; Prabhu, V; Rusu, I; Gros, S; Melian, E [Loyola University Medical Center, Maywood, IL (United States)

2016-06-15

Purpose: Frameless Stereotactic radiosurgery (SRS) is increasingly used in the clinic. Cone-Beam CT (CBCT) to simulation-CT match has replaced the 3-dimensional coordinate based set up using a stereotactic localizing frame. The SRS frame however served as both a localizing and immobilizing device. We seek to measure the quality of frameless (mask based) and frame based immobilization and evaluate its impact on target dose. Methods: Each SRS patient was set up by kV on-board imaging (OBI) and then fine-tuned with CBCT. A second CBCT was done at treatment-end to ascertain intrafraction motion. We compared pre- vs post-treatment CBCT shifts for both frameless and frame based SRS patients. CBCT to sim-CT fusion was repeated for each patient off-line to assess systematic residual image registration error. Each patient was re-planned with measured shifts to assess effects on target dose. Results: We analyzed 11 patients (12 lesions) treated with frameless SRS and 6 patients (11 lesions) with a fixed frame system. Average intra-fraction iso-center positioning errors for frameless and frame-based treatments were 1.24 ± 0.57 mm and 0.28 ± 0.08 mm (mean ± s.d.) respectively. Residual error in CBCT registration was 0.24 mm. The frameless positioning uncertainties led to target dose errors in Dmin and D95 of 15.5 ± 18.4% and 6.6 ± 9.1% respectively. The corresponding errors in fixed frame SRS were much lower with Dmin and D95 reduced by 4.2 ± 6.5% and D95 2.5 ± 3.8% respectively. Conclusion: Frameless mask provides good immobilization with average patient motion of 1.2 mm during treatment. This exceeds MRI voxel dimensions (∼0.43mm) used for target delineation. Frame-based SRS provides superior patient immobilization with measureable movement no greater than the background noise of the CBCT registration. Small lesions requiring submm precision are better served with a frame based SRS.

The SRS data bank concept

International Nuclear Information System (INIS)

Bendell, A.; Cannon, A.G.

1985-01-01

The Systems Reliability Service (SRS), now incorporated into the National Centre of Systems Reliability (NCSR), was formed 13 years ago as a commercial undertaking at the instigation of the then Minister of Technology, to act as a focal point for the development of reliability technology from its outset in the Nuclear Industry, and even earlier in such specialized areas as the instrument and aircraft industries. NCSR was also required to encourage research at Universities and other organizations, and a commercial service was offered to industry for solving various reliability and availability problems. The Data Bank Unit, being the data-handling, process and analysis group of the NCSR, is described. (author)

SU-F-T-640: Feasibility of Using a Commercially Available Surface Guided Radiotherapy System with An Open-Face SRS Immobilization System

Energy Technology Data Exchange (ETDEWEB)

Chinsky, B; Patel, R; Roeske, J; Surucu, M [Loyola University Medical Center, Maywood, IL (United States)

2016-06-15

Purpose: To evaluate the inherent accuracy of using a surface guided radiotherapy system (SGRT) in the setup and monitoring of patients receiving stereotactic radiosurgery with an open-face SRS immobilization system. Methods: An anthropomorphic head phantom was set up using the Qfix Encompass SRS Immobilization System on a Varian Edge with OSMS and Varian TrueBeam with AlignRT. The phantom was positioned at 0° gantry and couch. A reference image was acquired using the SGRT system and an ROI was created over the mask opening. The couch and gantry were rotated to different combinations focusing on clinically used SRS gantry/couch combinations and those blocking the SGRT cameras. Perceived surface deviation by the SGRT system from the reference image was recorded. A Winston-Lutz test was performed on couch angles tested and used to exclude couch walkout. The deviation magnitude was calculated using translational values and rotational raw values were recorded. Results: The maximum couch walkouts were: 0.4mm (Edge) and 0.5mm (TB). Solely rotating the gantry resulted in a median couch deviation of 0.2mm and range of 0.1–0.3mm for both linacs. Only rotating the couch (0° gantry) resulted in median deviations of 0.6mm and 0.5mm with ranges of 0.3–1.0mm and 0.3–0.7mm for the Edge and TB, respectively. Combining gantry and couch rotations, the median deviations were 0.7mm and 0.9mm with ranges of 0.3–1.1mm and 0.2–1.9mm for the Edge and TB, respectively. Including all combinations, rotation, roll, and pitch median deviations ranged from 0.1–0.3° with pitch demonstrating consistently higher values and a maximum deviation of 1.0° (both linacs). Conclusion: SGRT is a reliable monitoring tool, though taking into account system fluctuations, 1mm is too restrictive a site tolerance to use with the Qfix Encompass mask. Gantry rotation has little effect on system fluctuation even with camera blockage, whereas couch rotation has a larger effect.

SU-F-T-640: Feasibility of Using a Commercially Available Surface Guided Radiotherapy System with An Open-Face SRS Immobilization System

International Nuclear Information System (INIS)

Chinsky, B; Patel, R; Roeske, J; Surucu, M

2016-01-01

Purpose: To evaluate the inherent accuracy of using a surface guided radiotherapy system (SGRT) in the setup and monitoring of patients receiving stereotactic radiosurgery with an open-face SRS immobilization system. Methods: An anthropomorphic head phantom was set up using the Qfix Encompass SRS Immobilization System on a Varian Edge with OSMS and Varian TrueBeam with AlignRT. The phantom was positioned at 0° gantry and couch. A reference image was acquired using the SGRT system and an ROI was created over the mask opening. The couch and gantry were rotated to different combinations focusing on clinically used SRS gantry/couch combinations and those blocking the SGRT cameras. Perceived surface deviation by the SGRT system from the reference image was recorded. A Winston-Lutz test was performed on couch angles tested and used to exclude couch walkout. The deviation magnitude was calculated using translational values and rotational raw values were recorded. Results: The maximum couch walkouts were: 0.4mm (Edge) and 0.5mm (TB). Solely rotating the gantry resulted in a median couch deviation of 0.2mm and range of 0.1–0.3mm for both linacs. Only rotating the couch (0° gantry) resulted in median deviations of 0.6mm and 0.5mm with ranges of 0.3–1.0mm and 0.3–0.7mm for the Edge and TB, respectively. Combining gantry and couch rotations, the median deviations were 0.7mm and 0.9mm with ranges of 0.3–1.1mm and 0.2–1.9mm for the Edge and TB, respectively. Including all combinations, rotation, roll, and pitch median deviations ranged from 0.1–0.3° with pitch demonstrating consistently higher values and a maximum deviation of 1.0° (both linacs). Conclusion: SGRT is a reliable monitoring tool, though taking into account system fluctuations, 1mm is too restrictive a site tolerance to use with the Qfix Encompass mask. Gantry rotation has little effect on system fluctuation even with camera blockage, whereas couch rotation has a larger effect.

Effects of Different Student Response Modes on Science Learning

Science.gov (United States)

Kho, Lee Sze; Chen, Chwen Jen

2017-01-01

Student response systems (SRSs) are wireless answering devices that enable students to provide simple real-time feedback to instructors. This study aims to evaluate the effects of different SRS interaction modes on elementary school students' science learning. Three interaction modes which include SRS Individual, SRS Collaborative, and Classroom…

Orthogonal image pairs coupled with OSMS for noncoplanar beam angle, intracranial, single-isocenter, SRS treatments with multiple targets on the Varian Edge radiosurgery system

Directory of Open Access Journals (Sweden)

Jasmine A. Oliver, PhD

2017-07-01

Conclusion: Based on our study, CR-induced shifts with the Varian Edge radiosurgery system will not produce noticeable dosimetric effects for SRS treatments. Thus, replacing cone beam CT with orthogonal kV/kV pairs coupled with OSMS at the treatment couch angle could reduce the number of cone beam CT scans that are acquired during a standard SRS treatment while providing an accurate and safe treatment with negligible dosimetric effects on the treatment plan.

Potential for erosion corrosion of SRS high level waste tanks

International Nuclear Information System (INIS)

Zapp, P.E.

1994-01-01

SRS high-level radioactive waste tanks will not experience erosion corrosion to any significant degree during slurry pump operations. Erosion corrosion in carbon steel structures at reported pump discharge velocities is dominated by electrochemical (corrosion) processes. Interruption of those processes, as by the addition of corrosion inhibitors, sharply reduces the rate of metal loss from erosion corrosion. The well-inhibited SRS waste tanks have a near-zero general corrosion rate, and therefore will be essentially immune to erosion corrosion. The experimental data on carbon steel erosion corrosion most relevant to SRS operations was obtained at the Hanford Site on simulated Purex waste. A metal loss rate of 2.4 mils per year was measured at a temperature of 102 C and a slurry velocity comparable to calculated SRS slurry velocities on ground specimens of the same carbon steel used in SRS waste tanks. Based on these data and the much lower expected temperatures, the metal loss rate of SRS tanks under waste removal and processing conditions should be insignificant, i.e. less than 1 mil per year

Genetic labelling and application of the isoproturon-mineralizing Sphingomonas sp. strain SRS2 in soil and rhizosphere.

Science.gov (United States)

Kristensen, K E; Jacobsen, C S; Hansen, L H; Aamand, J; Morgan, J A W; Sternberg, C; Sørensen, S R

2006-09-01

To construct a luxAB-labelled Sphingomonas sp. strain SRS2 maintaining the ability to mineralize the herbicide isoproturon and usable for monitoring the survival and distribution of strain SRS2 on plant roots in laboratory systems. We inserted the mini-Tn5-luxAB marker into strain SRS2 using conjugational mating. In the transconjugant mutants luciferase was produced in varying levels. The mutants showed significant differences in their ability to degrade isoproturon. One luxAB-labelled mutant maintained the ability to mineralize isoproturon and was therefore selected for monitoring colonization of barley roots. We successfully constructed a genetically labelled isoproturon-mineralizing-strain SRS2 and demonstrated its ability to survive in soil and its colonization of rhizosphere. The construction of a luxAB-labelled strain SRS2 maintaining the degradative ability, provides a powerful tool for ecological studies serving as the basis for evaluating SRS2 as a bioremediation agent.

Development of a Rotary Microfilter for SRS HLW Applications

International Nuclear Information System (INIS)

MICHAEL, POIRIER

2005-01-01

The processing rate of Savannah River Site (SRS) high-level waste decontamination processes are limited by the flow rate of the solid-liquid separation. The baseline process, using a 0.1 micron cross-flow filter, produces approximately 0.02 gpm/sq. ft. of filtrate under expected operating conditions. Savannah River National Laboratory (SRNL) personnel identified the rotary microfilter as a technology that could significantly increase filter flux, with throughput improvements of as much as 10X for that specific operation. With funding from the U. S. Department of Energy Office of Cleanup Technology, SRNL personnel are evaluating and developing the rotary microfilter for radioactive service at SRS. This work includes pilot-scale and actual waste testing to evaluate system reliability, the impact of radiation on system components, the filter flux for a variety of waste streams, and relative performance for alternative filter media. Personnel revised the design for the disks and filter unit to make them suitable for high-level radioactive service

Refinement of MLC modeling improves commercial QA dosimetry system for SRS and SBRT patient-specific QA.

Science.gov (United States)

Hillman, Yair; Kim, Josh; Chetty, Indrin; Wen, Ning

2018-04-01

Mobius 3D (M3D) provides a volumetric dose verification of the treatment planning system's calculated dose using an independent beam model and a collapsed cone convolution superposition algorithm. However, there is a lack of investigation into M3D's accuracy and effectiveness for stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT) quality assurance (QA). Here, we collaborated with the vendor to develop a revised M3D beam model for SRS/SBRT cases treated with a 6X flattening filter-free (FFF) beam and high-definition multiple leaf collimator (HDMLC) on an Edge linear accelerator. Eighty SRS/SBRT cases, planned with AAA dose algorithm and validated with Gafchromic film, were compared to M3D dose calculations using 3D gamma analysis with 2%/2 mm gamma criteria and a 10% threshold. A revised beam model was developed by refining the HD-MLC model in M3D to improve small field dose calculation accuracy and beam profile agreement. All cases were reanalyzed using the revised beam model. The impact of heterogeneity corrections for lung cases was investigated by applying lung density overrides to five cases. For the standard and revised beam models, respectively, the mean gamma passing rates were 94.6% [standard deviation (SD): 6.1%] and 98.0% [SD: 1.7%] (for the overall patient), 88.2% [SD: 17.3%] and 93.8% [SD: 6.8%] (for the brain PTV), 71.4% [SD: 18.4%] and 81.5% [SD: 14.3%] (for the lung PTV), 83.3% [SD: 16.7%] and 67.9% [SD: 23.0%] (for the spine PTV), and 78.6% [SD: 14.0%] and 86.8% [SD: 12.5%] (for the PTV of all other sites). The lung PTV mean gamma passing rates improved from 74.1% [SD: 7.5%] to 89.3% [SD: 7.2%] with the lung density overridden. The revised beam model achieved an output factor within 3% of plastic scintillator measurements for 2 × 2 cm 2 MLC field size, but larger discrepancies are still seen for smaller field sizes which necessitate further improvement of the beam model. Special attention needs to be paid to small field

Initial clinical results of linac stereotactic radiosurgery (SRS) and stereotactic radiotherapy (SRT) for pituitary adenomas

International Nuclear Information System (INIS)

Mitsumori, Michihide; Shrieve, Dennis C.; Alexander, Eben; Kaiser, Ursula B.; Richardson, Gary E.; McL Black, Peter; Loeffler, Jay S.

1997-01-01

cases who received more than 1500 cGy at 80% isodose line. Target lesions were located in the cavernous sinus in all of 3 cases and 1 of the 3 cases had a history of conventional radiotherapy to the this area. There were no adverse effect observed in SRT cases (median follow up 30 months). None of the 48 patients developed neither new neurocognitive nor visual disorders. Endocriological effect: Hormonal adverse effects were similar for both groups, resulting 3-year freedom from newly initiated hormonal replacement 77.1 % and 79.9% (median follow up 41 months and 30 months) for SRS and SRT groups, respectively. Of note, 2 of the patients with ACTH producing tumor who underwent SRS showed a marked reduction of ACTH and resolution of Cushing syndrome within 1 year of SRS. Conclusion: 1) Both SRS and SRT achieved a similar high local control without developing new visual or neurocognitive disorders. 2) In SRS cases, care must be taken for the dose distribution in adjacent normal tissues, especially when treating a case with a lesion in the cavernous sinus or history of previous radiotherapy. 3) For hormonally active adenomas which is located more than 5 mm from optic chiasm or optic nerve, we would recommend SRS which appears to produce a more rapid hormonal response

SRS tank closure. Innovative technology summary report

International Nuclear Information System (INIS)

1999-08-01

High-level waste (HLW) tank closure technology is designed to stabilize any remaining radionuclides and hazardous constituents left in a tank after bulk waste removal. Two Savannah River Site (SRS) HLW tanks were closed after cleansing and then filling each tank with three layers of grout. The first layer consists of a chemically reducing grout. The fill material has chemical properties that retard the movement of some radionuclides and chemical constituents. A layer of controlled low-strength material (CLSM), a self-leveling fill material, is placed on top of the reducing grout. CLSM provides sufficient strength to support the overbearing weight. The final layer is a free-flowing, strong grout similar to normal concrete. After the main tank cavity is filled, risers are filled with grout, and all waste transfer piping connected to the tank is isolated. The tank ventilation system is dismantled, and the remaining systems are isolated. Equipment that remains with the tank is filled with grout. The tank and ancillary systems are left in a state requiring only limited surveillance. Administrative procedures are in place to control land use and access. DOE eventually plans to remove all of its HLW storage tanks from service. These tanks are located at SRS, Hanford, and Idaho National Engineering and Environmental Laboratory. Low-activity waste storage tanks at Oak Ridge Reservation are also scheduled for closure

Screening dynamic evaluation of SRS cooling water line

International Nuclear Information System (INIS)

Bezler, P.; Shteyngart, S.; Breidenbach, G.

1991-01-01

The production reactors at the Savannah River Site (SRS) have been shut down due to perceived safety concerns. A major concern is the seismic integrity of the plant. A comprehensive program is underway to assess the seismic capacity of the existing systems and components and to upgrade them to acceptable levels. The evaluation of the piping systems at the SRS is a major element of this program. Many of the piping systems at the production reactors were designed without performing dynamic analyses. Instead their design complied with good design practice for dead weight supported systems with proper accommodation of thermal expansion effects. In order to gain some insight as to the seismic capacity of piping installed in this fashion, dynamic analyses were performed for some lines. Since the piping was not seismically supported, the evaluations involved various approximations and the results are only used as a screening test of seismic adequacy. In this paper, the screening evaluations performed for the raw water inlet line are described. This line was selected for evaluation since it was considered typical of the smaller diameter piping systems at the plant. It is a dead weight supported system made up of a run of small diameter piping which extends for great distances over many dead weight supports and through wall penetrations. The results of several evaluations for the system using different approximations to represent the support system are described. 2 figs., 4 tabs

Repackaging SRS Black Box TRU Waste

International Nuclear Information System (INIS)

Swale, D. J.; Stone, K.A.; Milner, T. N.

2006-01-01

Historically, large items of TRU Waste, which were too large to be packaged in drums for disposal have been packaged in various sizes of custom made plywood boxes at the Savannah River Site (SRS), for many years. These boxes were subsequently packaged into large steel ''Black Boxes'' for storage at SRS, pending availability of Characterization and Certification capability, to facilitate disposal of larger items of TRU Waste. There are approximately 107 Black Boxes in inventory at SRS, each measuring some 18' x 12' x 7', and weighing up to 45,000 lbs. These Black Boxes have been stored since the early 1980s. The project to repackage this waste into Standard Large Boxes (SLBs), Standard Waste Boxes (SWB) and Ten Drum Overpacks (TDOP), for subsequent characterization and WIPP disposal, commenced in FY04. To date, 10 Black Boxes have been repackaged, resulting in 40 SLB-2's, and 37 B25 overpack boxes, these B25's will be overpacked in SLB-2's prior to shipping to WIPP. This paper will describe experience to date from this project

Defining the Glass Composition Limits for SRS Contaminated Soils

International Nuclear Information System (INIS)

Cicero, C.A.; Bickford, D.F.; Crews, W.O.

1995-01-01

Contaminated soil resulting from the excavation, repair, and decommissioning of facilities located at the Savannah River Site (SRS) is currently being disposed of by shallow land burial or is being stored when considered only hazardous. Vitrification of this waste is being investigated, since it will bind the hazardous and radioactive species in a stable and durable glass matrix, which will reduce the risk of ground water contamination. However, the composition limits for producing durable glass have to be determined before the technology can be applied. Glass compositions, consisting of SRS soil and glass forming additives, were tested on a crucible-scale in three ternary phase systems. Nine different glass compositions were produced, with waste loadings ranging from 43 to 58 weight percent. These were characterized using varoius chemical methods and tested for durability in both alkaline and acidic environments. All nine performed well in alkaline environments, but only three met the strictest criteria for the acidic environment tests. Although the glasses did not meet all of the limits for the acidic tests, the test was performed on very conservative size samples, so the results were also conservative. Therefore, enough evidence was found to provide proof that SRS soil can be vitrified in a durable glass matrix

Significance of Soft Zone Sediments at the SRS

Energy Technology Data Exchange (ETDEWEB)

Aadland, R.K.

2000-02-03

The purpose of this report is to provide information on the origin, extent and stability of ''soft zones'' in the carbonate bearing strata at the Savannah River Site (SRS). As part of this study, a comprehensive historical compendium of how soft zones have been addressed during the past 47 years at SRS is reviewed.

Solid Waste Information Tracking System (SWITS), Backlog Waste Modifications, Software Requirements Specification (SRS)

International Nuclear Information System (INIS)

Clark, R.E.

1995-01-01

Purpose of this document is to define the system requirements necessary to improve computer support for the WHC backlog waste business process through enhancements to the backlog waste function of the SWITS system. This SRS document covers enhancements to the SWITS system to support changes to the existing Backlog Waste screens including new data elements, label changes, and new pop-up screens. The pop-ups will allow the user to flag the processes that a waste container must have performed on it, and will provide history tracking of changes to data. A new screen will also be provided allowing Acceptable Services to perform mass updates to specific data in Backlog Waste table. The SWITS Backlog Waste enhancements in this document will support the project goals in WHC-SD-WM-003 and its Revision 1 (Radioactive Solid Waste Tracking System Conceptual Definition) for the control, tracing, and inventory management of waste as the packages are generated and moved through final disposal (cradle-to-grave)

The SRS analytical laboratories strategic plan

International Nuclear Information System (INIS)

Hiland, D.E.

1993-01-01

There is an acute shortage of Savannah River Site (SRS) analytical laboratory capacity to support key Department of Energy (DOE) environmental restoration and waste management (EM) programs while making the transition from traditional defense program (DP) missions as a result of the cessation of the Cold War. This motivated Westinghouse Savannah River Company (WSRC) to develop an open-quotes Analytical Laboratories Strategic Planclose quotes (ALSP) in order to provide appropriate input to SRS operating plans and justification for proposed analytical laboratory projects. The methodology used to develop this plan is applicable to all types of strategic planning

TRANSFORMING THE SRS ENVIRONMENTAL BUSINESS: COMMUNICATION AND APPLIED PROJECT MANAGEMENT PRINCIPLES

Energy Technology Data Exchange (ETDEWEB)

Saldivar, E.

2010-01-20

A process for communicating information relating to core business functions that also encourages improving internal communications has been established at SRS. This process continues to grow and strengthen as the multiple Contractors, Regulators and DOE-SR relationships mature. A number of management communication tools have been initiated, retooled, rebooted or continued with enhancements to ensure appropriate information is communicated to all levels with environmental responsibility at SRS. The types of information that are the focus of this improved process are feedback from the customer and from informational exchange forums (i.e., Challenge Opportunity and Resolution (COR), SRS Regulatory Integration Team (SRIT), Environmental Quality Management Division (EQMD), Senior Environmental Managers Council (SEMC), etc.). These forums, SRS environmental functions centralization, and the creation of a Regulatory Integration process allows for cross-functional decision making, problem solving and information sharing that involves the field organizations, Environmental Compliance Authorities (ECA), Subject Matter Experts (SME), DOE and the Regulators. Numerous examples of effective decision-making and problem solving will be shared. Lessons Learned involving inadequate communications and the resulting impacts on the environment, customer satisfaction, and relationships will also be discussed. Additionally, the focus on improved communications also includes maintaining awareness of business activities. The tools being utilized to facilitate the continuing improvement of internal communications include weekly staff meetings for all individuals within the organization, quarterly ECA and SME meeting, quarterly Regulatory Integration & Environmental Services (RI&ES) All-Hands meetings hosted by the Director, bi-weekly EQMD and EQMD Lite meetings with the customer, bi-annual SRIT meetings, and COR meetings on an as need basis. In addition, an existing Required Reading Program

Assessment of SRS ambient air monitoring network

Energy Technology Data Exchange (ETDEWEB)

Abbott, K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Jannik, T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2016-08-03

Three methodologies have been used to assess the effectiveness of the existing ambient air monitoring system in place at the Savannah River Site in Aiken, SC. Effectiveness was measured using two metrics that have been utilized in previous quantification of air-monitoring network performance; frequency of detection (a measurement of how frequently a minimum number of samplers within the network detect an event), and network intensity (a measurement of how consistent each sampler within the network is at detecting events). In addition to determining the effectiveness of the current system, the objective of performing this assessment was to determine what, if any, changes could make the system more effective. Methodologies included 1) the Waite method of determining sampler distribution, 2) the CAP88- PC annual dose model, and 3) a puff/plume transport model used to predict air concentrations at sampler locations. Data collected from air samplers at SRS in 2015 compared with predicted data resulting from the methodologies determined that the frequency of detection for the current system is 79.2% with sampler efficiencies ranging from 5% to 45%, and a mean network intensity of 21.5%. One of the air monitoring stations had an efficiency of less than 10%, and detected releases during just one sampling period of the entire year, adding little to the overall network intensity. By moving or removing this sampler, the mean network intensity increased to about 23%. Further work in increasing the network intensity and simulating accident scenarios to further test the ambient air system at SRS is planned

Language Teaching and Technology Forum: The Integration of a Student Response System in Flipped Classrooms

Science.gov (United States)

Hung, Hsiu-Ting

2017-01-01

The present study incorporates a student response system (SRS) as a means to engage students in a flipped classroom and promote active learning. While the effectiveness of such systems with regard to student learning has been well documented in disciplines that are dominated by lecture-based instruction, no studies have compared the effectiveness…

RIBDB: An SRS Based Infrastructure for REALIS

Directory of Open Access Journals (Sweden)

Antoine de Daruvar

2006-04-01

Full Text Available The REALIS project is an EU-funded consortium for the post genomic analysis of the food pathogen Listeria monocytogenes. The data generated by the consortium members is stored under the RIBDB database, a system built using SRS which integrates consortium data, public databases, and applications for analysis. RIBDB is available to all consortium members through a web server, with the option of installing a local mirror of the main server for local analysis.

SU-E-T-480: Radiobiological Dose Comparison of Single Fraction SRS, Multi-Fraction SRT and Multi-Stage SRS of Large Target Volumes Using the Linear-Quadratic Formula

International Nuclear Information System (INIS)

Ding, C; Hrycushko, B; Jiang, S; Meyer, J; Timmerman, R

2014-01-01

Purpose: To compare the radiobiological effect on large tumors and surrounding normal tissues from single fraction SRS, multi-fractionated SRT, and multi-staged SRS treatment. Methods: An anthropomorphic head phantom with a centrally located large volume target (18.2 cm 3 ) was scanned using a 16 slice large bore CT simulator. Scans were imported to the Multiplan treatment planning system where a total prescription dose of 20Gy was used for a single, three staged and three fractionated treatment. Cyber Knife treatment plans were inversely optimized for the target volume to achieve at least 95% coverage of the prescription dose. For the multistage plan, the target was segmented into three subtargets having similar volume and shape. Staged plans for individual subtargets were generated based on a planning technique where the beam MUs of the original plan on the total target volume are changed by weighting the MUs based on projected beam lengths within each subtarget. Dose matrices for each plan were export in DICOM format and used to calculate equivalent dose distributions in 2Gy fractions using an alpha beta ratio of 10 for the target and 3 for normal tissue. Results: Singe fraction SRS, multi-stage plan and multi-fractionated SRT plans had an average 2Gy dose equivalent to the target of 62.89Gy, 37.91Gy and 33.68Gy, respectively. The normal tissue within 12Gy physical dose region had an average 2Gy dose equivalent of 29.55Gy, 16.08Gy and 13.93Gy, respectively. Conclusion: The single fraction SRS plan had the largest predicted biological effect for the target and the surrounding normal tissue. The multi-stage treatment provided for a more potent biologically effect on target compared to the multi-fraction SRT treatments with less biological normal tissue than single-fraction SRS treatment

Comparison of Srs-24 And Srs-22 Scores in Thirty Eight Adolescent Idiopathic Scoliosis Patients Who Had Undergone Surgical Correction

OpenAIRE

CYW Chan; LB Saw; MK Kwan

2009-01-01

Adolescent idiopathic scoliosis is a spinal deformity that affects patients’ self image and confidence. Surgery is offered when the curvature is greater than 50 degrees based on the likelihood of curvature progression. Outcome measures for scoliosis correction can be described in terms of radiological improvement or improvement of health related quality of life scores. The Scoliosis Research Society 22 (SRS-22) and Scoliosis Research Society 24 (SRS-24) questionnaires are widely accepted and ...

SU-G-TeP2-12: IROCHouston and MDAPL SRS Anthropomorphic Phantom Results

International Nuclear Information System (INIS)

Molineu, A; Kry, S; Alvarez, P; Hernandez, N; Nguyen, T; Followill, D

2016-01-01

Purpose: To report the results of SRS phantom irradiations Methods: Anthropomorphic SRS head phantoms were sent to institutions participating in NCI sponsored SRS clinical trials and institutions interested in verifying SRS treatment delivery. The phantom shell was purchased from Phantom Laboratory and altered to house dosimetry and imaging inserts. The imaging insert has 1.9 cm diameter spherical target. The dosimetry insert holds two TLD capsules and radiochromic film in the coronal and sagittal planes through the center of the target. Institutions were asked to image, plan and treat the phantom as they would an SRS patient. GammaKnife, CyberKnife and c-arm accelerator institutions were asked to cover the target with 15 Gy, 20 Gy and 25 Gy, respectively. Following these guidelines and typical planning protocols for these three types of machines gives roughly 30 Gy to the center of the target for all units. Submission of the DICOM digital data set was required for analysis. Criteria of 5% for TLD results and 85% of pixels passing 5%/3mm gamma analysis were applied beginning in 2013. Results: The phantom was analyzed 269 times between the beginning of 2013 to present. The pass rate is 81%. Nineteen of the irradiation results failed only the TLD criteria, 19 failed only the film criteria and 12 failed both. Irradiations included 32 CyberKnife 23 GammaKnife, 3 TomoTherapy and 211 c-arm units. Planning systems included Eclipse, Ergo, GammaPlan, Hi-Art, iPlan, Monaco, MultiPlan, Pinnacle, RayStation, XiO and XKnife. Irradiations that were not accompanied with DICOM data were not included in this analysis. Conclusion: The phantom is a valuable end-to-end test used to independently verify the accuracy of SRS treatment delivery. This investigation was supported by IROC grant CA180803 awarded by the NCI.

Groundwater Treatment at SRS: An Innovative Approach

International Nuclear Information System (INIS)

Jorque, M.A.; Golshir, G.H.; Davis, B.

1998-03-01

The SRS is located in southwestern South Carolina, occupying an almost circular area of approximately 800 km2 within Aiken, Barnwell, and Allendale counties. The site lies approximately 36 km southeast of Augusta, Georgia, and is bounded by the Savannah River along its southwestern border. Prior to the establishment of the SRS in 1952, the area was largely a rural agricultural community. As part of the defense complex, the SRS produced special nuclear materials for the national defense.From 1955 until 1988, unlined earthen basins were used to dispose of wastewater from the SRS separations facilities located in the F and H areas. Approximately 300 million liters of wastewater was transported annually from the process area through underground piping to the basins. The wastewater was allowed to evaporate and to seep into the underlying formations. There were three basins in the F-Area covering a total of about 3 hectares; while the H-Area was served by four basins covering about 6 hectares. The seepage basins closure was started in 1989 and SCDHEC certified the closures as completed in 1991.Groundwater monitoring conducted in accordance with the provisions of the RCRA Permits determined that the underlying hydrogeologic units were contaminated by tritium, radioactive metals (primarily Cesium 137, Strontium 90, and Uranium 235), nitrate and heavy metals, some of which are defined as hazardous by RCRA. Under the terms and conditions of the RCRA Post- Closure Permits, it was necessary to remediate the contaminated groundwater plumes

Stabilizing And Packaging Pu Materials Per 3013 At SRS

International Nuclear Information System (INIS)

STEVE, HENSEL

2005-01-01

The Savannah River Site (SRS) began packaging Pu metals into 3013 containers in April, 2003 and oxides in October, 2003. A total of 919 outer 3013 containers were made in the FB-Line at SRS when stabilization and packaging was completed in January, 2005. Experiences, lessons learned, and an overview of packaging activities are presented

Genome-centric evaluation of Burkholderia sp. strain SRS-W-2-2016 resistant to high concentrations of uranium and nickel isolated from the Savannah River Site (SRS, USA

Directory of Open Access Journals (Sweden)

Ashish Pathak

2017-06-01

Full Text Available Savannah River Site (SRS, an approximately 800-km2 former nuclear weapons production facility located near Aiken, SC remains co-contaminated by heavy metals and radionuclides. To gain a better understanding on microbially-mediated bioremediation mechanisms, several bacterial strains resistant to high concentrations of Uranium (U and Nickel (Ni were isolated from the Steeds Pond soils located within the SRS site. One of the isolated strains, designated as strain SRS-W-2-2016, grew robustly on both U and Ni. To fully understand the arsenal of metabolic functions possessed by this strain, a draft whole genome sequence (WGS was obtained, assembled, annotated and analyzed. Genome-centric evaluation revealed the isolate to belong to the Burkholderia genus with close affiliation to B. xenovorans LB400, an aggressive polychlorinated biphenyl-degrader. At a coverage of 90×, the genome of strain SRS-W-2-2016 consisted of 8,035,584 bases with a total number of 7071 putative genes assembling into 191 contigs with an N50 contig length of 134,675 bases. Several gene homologues coding for resistance to heavy metals/radionuclides were identified in strain SRS-W-2-2016, such as a suite of outer membrane efflux pump proteins similar to nickel/cobalt transporter regulators, peptide/nickel transport substrate and ATP-binding proteins, permease proteins, and a high-affinity nickel-transport protein. Also noteworthy were two separate gene fragments in strain SRS-W-2-2016 homologous to the spoT gene; recently correlated with bacterial tolerance to U. Additionally, a plethora of oxygenase genes were also identified in the isolate, potentially involved in the breakdown of organic compounds facilitating the strain's successful colonization and survival in the SRS co-contaminated soils. The WGS project of Burkholderia sp. strain SRS-W-2-2016 is available at DDBJ/ENA/GenBank under the accession #MSDV00000000.

Testing of SRS and RFETS Nylon Bag Material

International Nuclear Information System (INIS)

Laurinat, J.E.

1998-01-01

This report compares the effects of radiation and heating on nylon bagout materials used at the Savannah River Site (SRS) and the Rocky Flats Environmental Technology Site (RFETS). Recently, to simplify the processing of sand, slag, and crucible (SS and C), FB-Line has replaced the low-density polyethylene (LDPE) and polyvinyl chloride (PVC) bags normally used to package cans of plutonium-bearing material with nylon bags. LDPE and PVC are not soluble in the nitric acid dissolver solution used in F-Canyon, so cans bagged using these materials had to be repackaged before they were added to the dissolver. Because nylon dissolves in nitric acid, cans bagged in nylon can be charged to the F-Canyon dissolvers without repackaging, thereby reducing handling requirements and personnel exposure. As part of a program to process RFETS SS and C at SRS, RFETS has also begun to use a nylon bagout material. The RFETS bag materials is made from a copolymer of nylon 6 and nylon 6.9, while the SRS material is made from a nylon 6 monomer. In addition, the SRS nylon has an anti-static agent added. The RFETS nylon is slightly softer than the SRS nylon, but does not appear to be as resistant to flex cracks initiated by contact with sharp corners of the inner can containing the SS and C.2 FB-Line Operations has asked for measurement of the effects of radiation and heating on these materials. Specifically, they have requested a comparison of the material properties of the plastics before and after irradiation, a measurement of the amount of outgassing when the plastics are heated, and a calculation of the amount of radiolytic gas generation. Testing was performed on samples taken from material that is currently used in FB-Line (color coded orange) and at RFETS. The requested tests are the same tests previously performed on the original and replacement nylon and LDPE bag materials.3,4,5. To evaluate the effect of irradiation on material properties, tensile stresses and elongations to break

Magnetism in the p-type Monolayer II-VI semiconductors SrS and SrSe

Science.gov (United States)

Lin, Heng-Fu; Lau, Woon-Ming; Zhao, Jijun

2017-01-01

Using density functional theory calculations, we study the electronic and magnetic properties of the p-type monolayer II-VI semiconductors SrX (X = S,Se). The pristine SrS and SrSe monolayers are large band gap semiconductor with a very flat band in the top valence band. Upon injecting hole uniformly, ferromagnetism emerges in those system in a large range of hole density. By varying hole density, the systems also show complicated phases transition among nonmagnetic semiconductor, half metal, magnetic semiconductor, and nonmagnetic metal. Furthermore, after introducing p-type dopants in SrS and SrSe via substitutionary inserting P (or As) dopants at the S (or Se) sites, local magnetic moments are formed around the substitutional sites. The local magnetic moments are stable with the ferromagnetic order with appreciable Curie temperature. The ferromagnetism originates from the instability of the electronic states in SrS and SrSe with the large density of states at the valence band edge, which demonstrates a useful strategy for realizing the ferromagnetism in the two dimensional semiconductors. PMID:28378761

Genetic labelling and application of the isoproturon-mineralizing Sphingomonas sp. strain SRS2 in soil and rhizosphere

DEFF Research Database (Denmark)

Kristensen, K.E.; Jacobsen, C.S.; Hansen, L.H.

2006-01-01

AIMS: To construct a luxAB-labelled Sphingomonas sp. strain SRS2 maintaining the ability to mineralize the herbicide isoproturon and usable for monitoring the survival and distribution of strain SRS2 on plant roots in laboratory systems. METHODS AND RESULTS: We inserted the mini-Tn5-luxAB marker...... into strain SRS2 using conjugational mating. In the transconjugant mutants luciferase was produced in varying levels. The mutants showed significant differences in their ability to degrade isoproturon. One luxAB-labelled mutant maintained the ability to mineralize isoproturon and was therefore selected...... for monitoring colonization of barley roots. CONCLUSIONS: We successfully constructed a genetically labelled isoproturon-mineralizing-strain SRS2 and demonstrated its ability to survive in soil and its colonization of rhizosphere. SIGNIFICANCE AND IMPACT OF THE STUDY: The construction of a luxAB-labelled strain...

Shedding new light on lipid functions with CARS and SRS microscopy

Science.gov (United States)

Yu, Yong; Ramachandran, Prasanna V.; Wang, Meng C.

2014-01-01

Modern optical microscopy has granted biomedical scientists unprecedented access to the inner workings of a cell, and revolutionized our understanding of the molecular mechanisms underlying physiological and disease states. In spite of these advances, however, visualization of certain classes of molecules (e.g. lipids) at the sub-cellular level has remained elusive. Recently developed chemical imaging modalities – Coherent Anti-Stokes Raman Scattering (CARS) microscopy and Stimulated Raman Scattering (SRS) microscopy – have helped bridge this gap. By selectively imaging the vibration of a specific chemical group, these non-invasive techniques allow high-resolution imaging of individual molecules in vivo, and circumvent the need for potentially perturbative extrinsic labels. These tools have already been applied to the study of fat metabolism, helping uncover novel regulators of lipid storage. Here we review the underlying principle of CARS and SRS microscopy, and discuss the advantages and caveats of each technique. We also review recent applications of these tools in the study of lipids as well as other biomolecules, and conclude with a brief guide for interested researchers to build and use CARS/SRS systems for their own research. PMID:24576891

Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis

International Nuclear Information System (INIS)

Burkovics, Peter; Sebesta, Marek; Kolesar, Peter; Sisakova, Alexandra; Marini, Victoria; Plault, Nicolas; Szukacsov, Valeria; Pinter, Lajos; Haracska, Lajos; Robert, Thomas; Kolesar, Peter; Gangloff, Serge; Krejci, Lumir

2013-01-01

Completion of DNA replication needs to be ensured even when challenged with fork progression problems or DNA damage. PCNA and its modifications constitute a molecular switch to control distinct repair pathways. In yeast, SUMOylated PCNA (S-PCNA) recruits Srs2 to sites of replication where Srs2 can disrupt Rad51 filaments and prevent homologous recombination (HR). We report here an unexpected additional mechanism by which S-PCNA and Srs2 block the synthesis-dependent extension of a recombination intermediate, thus limiting its potentially hazardous resolution in association with a cross-over. This new Srs2 activity requires the SUMO interaction motif at its C-terminus, but neither its translocase activity nor its interaction with Rad51. Srs2 binding to S-PCNA dissociates Polδ and Polη from the repair synthesis machinery, thus revealing a novel regulatory mechanism controlling spontaneous genome rearrangements. Our results suggest that cycling cells use the Siz1-dependent SUMOylation of PCNA to limit the extension of repair synthesis during template switch or HR and attenuate reciprocal DNA strand exchanges to maintain genome stability. (authors)

The Interaction of Pedagogical Approach, Gender, Self-Regulation, and Goal Orientation Using Student Response System Technology

Science.gov (United States)

Edens, Kellah M.

2008-01-01

This research compares a behaviorally based approach for using electronic student response system (SRS) technology with a metacognitive-oriented approach to determine effects on attendance, preparation for class, and achievement. Also examined are the interaction effects of pedagogical approach with self-regulatory and motivational characteristics…

Growth in coculture stimulates metabolism of the phenylurea herbicide isoproturon by Sphingomonas sp. strain SRS2.

Science.gov (United States)

Sørensen, Sebastian R; Ronen, Zeev; Aamand, Jens

2002-07-01

Metabolism of the phenylurea herbicide isoproturon by Sphingomonas sp. strain SRS2 was significantly enhanced when the strain was grown in coculture with a soil bacterium (designated strain SRS1). Both members of this consortium were isolated from a highly enriched isoproturon-degrading culture derived from an agricultural soil previously treated regularly with the herbicide. Based on analysis of the 16S rRNA gene, strain SRS1 was assigned to the beta-subdivision of the proteobacteria and probably represents a new genus. Strain SRS1 was unable to degrade either isoproturon or its known metabolites 3-(4-isopropylphenyl)-1-methylurea, 3-(4-isopropylphenyl)-urea, or 4-isopropyl-aniline. Pure culture studies indicate that Sphingomonas sp. SRS2 is auxotrophic and requires components supplied by association with other soil bacteria. A specific mixture of amino acids appeared to meet these requirements, and it was shown that methionine was essential for Sphingomonas sp. SRS2. This suggests that strain SRS1 supplies amino acids to Sphingomonas sp. SRS2, thereby leading to rapid metabolism of (14)C-labeled isoproturon to (14)CO(2) and corresponding growth of strain SRS2. Proliferation of strain SRS1 suggests that isoproturon metabolism by Sphingomonas sp. SRS2 provides unknown metabolites or cell debris that supports growth of strain SRS1. The role of strain SRS1 in the consortium was not ubiquitous among soil bacteria; however, the indigenous soil microflora and some strains from culture collections also stimulate isoproturon metabolism by Sphingomonas sp. strain SRS2 to a similar extent.

SRS ES ampersand H standards compliance program management plan

International Nuclear Information System (INIS)

Hearn, W.H.

1993-01-01

On March 8, 1990, the Defense Nuclear Facilities Safety Board (DNFSB) issued Recommendation 90-2 to the Secretary of Energy. This recommendation, based upon the DNFSB's initial review and evaluation of the content and implementation of standards relating to the design, construction, operations, and decommissioning of defense nuclear facilities of the Department of Energy (DOE), called for three actions: (1) identification of specific standards that apply to design, construction, operation and decommissioning of DOE facilities; (2) assessment of the adequacy of those standards for protecting public health and safety; and (3) determination of the extent to which they have and are being implemented. This document defines the elements of the SRS program required to support the HQ program in response to DNFSB Recommendation 90-2. The objective is to ensure a consistent approach for all sitewide ES and H Standards Compliance Program efforts that satisfied the intent of Recommendation 90-2 and the HQ 90-2 Implementation Plan in a cost-effective manner. The methodology and instructions for implementation of the SRS program are contained in the Standards Compliance Program Implementation Plan. The Management Plan shall be used in conjunction with the Implementation Plan

Volumetric activity of SRS mixed waste and comparison with SRS performance and commercial facility limits

International Nuclear Information System (INIS)

Ades, M.J.; Daugherty, B.A.; Cook, J.R.

1996-01-01

This paper discusses the comparative analysis performed to estimate the after-treatment volumetric activity of the radionuclides included in the Savannah River site (SRS) mixed-waste streams and its comparison with the following: (1) The performance evaluation (PE) limits established for each radionuclide for on-site disposal: These limits correspond to the permissible waste disposal limits that are the lowest limits evaluated for the most restrictive release scenarios that include the groundwater pathway, the atmospheric pathway, and the intruder scenarios. (2) The radiological performance assessment (PA) limits established for each radionuclide for disposal in the SRS disposal vaults that meet the requirements of Chap. III of the U.S. Department of Energy Order 5820.2A: The vaults considered are the low-activity waste (LAW) vaults, the intermediate-level non-tritium (ILNT) vaults. and the intermediate-level tritium (ILT) vaults. (3) The radioactive limits of a commercial mixed waste disposal facility

ENVIRONMENTAL ASSESSMENT FOR THE NPDES STORM WATER COMPLIANCE ALTERNATIVES AT THE SRS

International Nuclear Information System (INIS)

Shedrow, C

2006-01-01

The U.S. Department of Energy (DOE) prepared this environmental assessment (EA) to evaluate the potential environmental impacts associated with proposed and alternative actions to achieve water quality permit compliance at 38 storm water outfalls located at the Savannah River Site (SRS) (Figure 1-1). Effluent monitoring data indicates that some of these outfalls may not presently comply with new National Pollutant Discharge Elimination System (NPDES) Storm Water General Permit effluent standards that became effective July 1, 2005 (SCR000000). The NPDES permit requires that best management practices (BMPs) be implemented and maintained, as necessary, to ensure that storm water discharges at SRS do not cause or contribute to the contravention of applicable state water quality standards (WQS)

ENVIRONMENTAL ASSESSMENT FOR THE NPDES STORM WATER COMPLIANCE ALTERNATIVES AT THE SRS

Energy Technology Data Exchange (ETDEWEB)

Shedrow, C

2006-11-01

The U.S. Department of Energy (DOE) prepared this environmental assessment (EA) to evaluate the potential environmental impacts associated with proposed and alternative actions to achieve water quality permit compliance at 38 storm water outfalls located at the Savannah River Site (SRS) (Figure 1-1). Effluent monitoring data indicates that some of these outfalls may not presently comply with new National Pollutant Discharge Elimination System (NPDES) Storm Water General Permit effluent standards that became effective July 1, 2005 (SCR000000). The NPDES permit requires that best management practices (BMPs) be implemented and maintained, as necessary, to ensure that storm water discharges at SRS do not cause or contribute to the contravention of applicable state water quality standards (WQS).

ASD Screening Measures for High-Ability Youth with ASD: Examining the ASSQ and SRS

Science.gov (United States)

Cederberg, Charles D.; Gann, Lianne C.; Foley-Nicpon, Megan; Sussman, Zachary

2018-01-01

High-ability youth diagnosed with autism spectrum disorder (ASD) historically have been neglected within samples validating ASD screening measures, and consensus for what constitutes high ability has not been established. The Autism Spectrum Screening Questionnaire (ASSQ) and Social Responsiveness Scale (SRS) are two common screening tools for ASD…

Srs2 and Mus81-Mms4 Prevent Accumulation of Toxic Inter-Homolog Recombination Intermediates.

Directory of Open Access Journals (Sweden)

Kenji Keyamura

2016-07-01

Full Text Available Homologous recombination is an evolutionally conserved mechanism that promotes genome stability through the faithful repair of double-strand breaks and single-strand gaps in DNA, and the recovery of stalled or collapsed replication forks. Saccharomyces cerevisiae ATP-dependent DNA helicase Srs2 (a member of the highly conserved UvrD family of helicases has multiple roles in regulating homologous recombination. A mutation (srs2K41A resulting in a helicase-dead mutant of Srs2 was found to be lethal in diploid, but not in haploid, cells. In diploid cells, Srs2K41A caused the accumulation of inter-homolog joint molecule intermediates, increased the levels of spontaneous Rad52 foci, and induced gross chromosomal rearrangements. Srs2K41A lethality and accumulation of joint molecules were suppressed by inactivating Rad51 or deleting the Rad51-interaction domain of Srs2, whereas phosphorylation and sumoylation of Srs2 and its interaction with sumoylated proliferating cell nuclear antigen (PCNA were not required for lethality. The structure-specific complex of crossover junction endonucleases Mus81 and Mms4 was also required for viability of diploid, but not haploid, SRS2 deletion mutants (srs2Δ, and diploid srs2Δ mus81Δ mutants accumulated joint molecule intermediates. Our data suggest that Srs2 and Mus81-Mms4 have critical roles in preventing the formation of (or in resolving toxic inter-homolog joint molecules, which could otherwise interfere with chromosome segregation and lead to genetic instability.

The electron gun for the Daresbury SRS linac

International Nuclear Information System (INIS)

Dykes, D.M.

1996-01-01

The electron gun for the Daresbury SRS linac injector has been modified to use the cathode-grid assembly from the Eimac planar triode 8755. The gun now has improved beam characteristics, is more reliable and the cathode assembly is quicker and easier to change. This paper describes the assembly of the electron gun, and then the re-conditioning of the cathode highlighting the vacuum environment. The action of the grid modulation system on the electron beam, which pre-bunches the electron beam, is described, and typical gun characteristics are shown. Proposed developments to the gun system are discussed. (author)

Poster - 43: Analysis of SBRT and SRS dose verification results using the Octavius 1000SRS detector

Energy Technology Data Exchange (ETDEWEB)

Cherpak, Amanda [Nova Scotia Cancer Centre, Nova Scotia Health Authority, Halifax, NS, Department of Radiation Oncology, Dalhousie University, Halifax, NS, Department of Physics and Atmospheric Sciences, Dalhousie University, Halifax, NS (Canada)

2016-08-15

Purpose: The Octavius 1000{sup SRS} detector was commissioned in December 2014 and is used routinely for verification of all SRS and SBRT plans. Results of verifications were analyzed to assess trends and limitations of the device and planning methods. Methods: Plans were delivered using a True Beam STx and results were evaluated using gamma analysis (95%, 3%/3mm) and absolute dose difference (5%). Verification results were analyzed based on several plan parameters including tumour volume, degree of modulation and prescribed dose. Results: During a 12 month period, a total of 124 patient plans were verified using the Octavius detector. Thirteen plans failed the gamma criteria, while 7 plans failed based on the absolute dose difference. When binned according to degree of modulation, a significant correlation was found between MU/cGy and both mean dose difference (r=0.78, p<0.05) and gamma (r=−0.60, p<0.05). When data was binned according to tumour volume, the standard deviation of average gamma dropped from 2.2% – 3.7% for the volumes less than 30 cm{sup 3} to below 1% for volumes greater than 30 cm{sup 3}. Conclusions: The majority of plans and verification failures involved tumour volumes smaller than 30 cm{sup 3}. This was expected due to the nature of disease treated with SBRT and SRS techniques and did not increase rate of failure. Correlations found with MU/cGy indicate that as modulation increased, results deteriorated but not beyond the previously set thresholds.

The development of optimization protocol in SRS

International Nuclear Information System (INIS)

Oh, S. J.; Suh, T. S.; Lee, H. K.; Choe, B. Y.

2002-01-01

In an operation of stereotactic radiosurgery(SRS), a high dose must be delivered to a target region while a normal tissue region must be spared. Using dose distribution which fits in a target region satisfies this purpose. This is solved by using data bases through the simple patient model simulating the brain model and the tumor region. The objective of this research is to develop brain model with tumor based on pseudo coordinate and systematic optimization protocol and to construct data base(DB) about beam parameters such as position and number of isocenter and collimator size. The normal tissue region of patient can be spared by DB in a operation of SRS

The development of optimization protocol in SRS

Energy Technology Data Exchange (ETDEWEB)

Oh, S. J.; Suh, T. S.; Lee, H. K.; Choe, B. Y. [The Catholic Univ., of Korea, Seoul (Korea, Republic of)

2002-07-01

In an operation of stereotactic radiosurgery(SRS), a high dose must be delivered to a target region while a normal tissue region must be spared. Using dose distribution which fits in a target region satisfies this purpose. This is solved by using data bases through the simple patient model simulating the brain model and the tumor region. The objective of this research is to develop brain model with tumor based on pseudo coordinate and systematic optimization protocol and to construct data base(DB) about beam parameters such as position and number of isocenter and collimator size. The normal tissue region of patient can be spared by DB in a operation of SRS.

Evaluation of the Validity of Groundwater Samples Obtained Using the Purge Water Management System at SRS

International Nuclear Information System (INIS)

Beardsley, C.C.

1999-01-01

As part of the demonstration testing of the Purge Water Management System (PWMS) technology at the Savannah River Site (SRS), four wells were equipped with PWMS units in 1997 and a series of sampling events were conducted at each during 1997-1998. Three of the wells were located in A/M Area while the fourth was located at the Old Radioactive Waste Burial Ground in the General Separations Area.The PWMS is a ''closed-loop'', non-contact, system used to collect and return purge water to the originating aquifer after a sampling event without having significantly altered the water quality. One of the primary concerns as to its applicability at SRS, and elsewhere, is whether the PWMS might resample groundwater that is returned to the aquifer during the previous sampling event. The purpose of the present investigation was to compare groundwater chemical analysis data collected at the four test wells using the PWMS vs. historical data collected using the standard monitoring program methodology to determine if the PWMS provides representative monitoring samples.The analysis of the groundwater chemical concentrations indicates that the PWMS sampling methodology acquired representative groundwater samples at monitoring wells ABP-1A, ABP-4, ARP-3 and BGO-33C. Representative groundwater samples are achieved if the PWMS does not resample groundwater that has been purged and returned during a previous sampling event. Initial screening calculations, conducted prior to the selection of these four wells, indicated that groundwater velocities were high enough under the ambient hydraulic gradients to preclude resampling from occurring at the time intervals that were used at each well. Corroborating evidence included a tracer test that was conducted at BGO-33C, the high degree of similarity between analyte concentrations derived from the PWMS samples and those obtained from historical protocol sampling, as well as the fact that PWMS data extend all previously existing concentration

MTR radiological database for SRS spent nuclear fuel facilities

International Nuclear Information System (INIS)

Blanchard, A.

2000-01-01

A database for radiological characterization of incoming Material Test Reactor (MTR) fuel has been developed for application to the Receiving Basin for Offsite Fuels (RBOF) and L-Basin spent fuel storage facilities at the Savannah River Site (SRS). This database provides a quick quantitative check to determine if SRS bound spent fuel is radiologically bounded by the Reference Fuel Assembly used in the L-Basin and RBOF authorization bases. The developed database considers pertinent characteristics of domestic and foreign research reactor fuel including exposure, fuel enrichment, irradiation time, cooling time, and fuel-to-moderator ratio. The supplied tables replace the time-consuming studies associated with authorization of SRS bound spent fuel with simple hand calculations. Additionally, the comprehensive database provides the means to overcome resource limitations, since a series of simple, yet conservative, hand calculations can now be performed in a timely manner and replace computational and technical staff requirements

Vitrification of actinide solutions in SRS separations facilities

International Nuclear Information System (INIS)

Minichan, R.L.; Ramsey, W.G.

1995-01-01

The actinide vitrification system being developed at SRS provides the capability to convert specialized or unique forms of nuclear material into a stable solid glass product that can be safely shipped, stored or reprocessed according to the DOE complex mission. This project is an application of technology developed through funds from the Office of Technology Development (OTD). This technology is ideally suited for vitrifying relatively small quantities of fissile or special nuclear material since it is designed to be critically safe. Successful demonstration of this system to safely vitrify radioactive material could open up numerous opportunities for transferring this technology to applications throughout the DOE complex

SRS ecology: Environmental information document

Energy Technology Data Exchange (ETDEWEB)

Wike, L.D.; Shipley, R.W.; Bowers, J.A. [and others

1993-09-01

The purpose of this Document is to provide a source of ecological information based on the exiting knowledge gained from research conducted at the Savannah River Site. This document provides a summary and synthesis of ecological research in the three main ecosystem types found at SRS and information on the threatened and endangered species residing there.

SRS ecology: Environmental information document

International Nuclear Information System (INIS)

Wike, L.D.; Shipley, R.W.; Bowers, J.A.

1993-09-01

The purpose of this Document is to provide a source of ecological information based on the exiting knowledge gained from research conducted at the Savannah River Site. This document provides a summary and synthesis of ecological research in the three main ecosystem types found at SRS and information on the threatened and endangered species residing there

TU-A-BRB-00: PANEL DISCUSSION: SBRT/SRS Case Studies - Brain and Spine

Energy Technology Data Exchange (ETDEWEB)

NONE

2016-06-15

Brain stereotactic radiosurgery (SRS) and spine stereotactic body radiation therapy (SBRT) are commonly treated by a multidisciplinary team of neurosurgeons, radiation oncologists, and medical physicists. However the treatment objectives, constraints, and technical considerations involved can be quite different between the two techniques. In this interactive session an expert panel of speakers will present clinical brain SRS and spine SBRT cases in order to demonstrate real-world considerations for ensuring safe and accurate treatment delivery and to highlight the significant differences in approach for each treatment site. The session will include discussion of topic such as clinical indications, immobilization, target definition, normal tissue tolerance limits, and beam arrangements. Learning Objectives: Understand the differences in indications and dose/fractionation strategies for intracranial SRS and spine SBRT. Describe the different treatment modalities which can be used to deliver intracranial SRS and spine SBRT. Cite the major differences in treatment setup and delivery principles between intracranial and spine treatments. Identify key critical structures and clinical dosimetric tolerance levels for spine SBRT and intracranial SRS. Understand areas of ongoing work to standardize intracranial SRS and spine SBRT procedures. Schlesinger: Research support: Elekta Instruments, AB; D. Schlesinger, Elekta Instruments, AB - research support; B. Winey, No relevant external funding for this subject.

TU-A-BRB-00: PANEL DISCUSSION: SBRT/SRS Case Studies - Brain and Spine

International Nuclear Information System (INIS)

2016-01-01

Brain stereotactic radiosurgery (SRS) and spine stereotactic body radiation therapy (SBRT) are commonly treated by a multidisciplinary team of neurosurgeons, radiation oncologists, and medical physicists. However the treatment objectives, constraints, and technical considerations involved can be quite different between the two techniques. In this interactive session an expert panel of speakers will present clinical brain SRS and spine SBRT cases in order to demonstrate real-world considerations for ensuring safe and accurate treatment delivery and to highlight the significant differences in approach for each treatment site. The session will include discussion of topic such as clinical indications, immobilization, target definition, normal tissue tolerance limits, and beam arrangements. Learning Objectives: Understand the differences in indications and dose/fractionation strategies for intracranial SRS and spine SBRT. Describe the different treatment modalities which can be used to deliver intracranial SRS and spine SBRT. Cite the major differences in treatment setup and delivery principles between intracranial and spine treatments. Identify key critical structures and clinical dosimetric tolerance levels for spine SBRT and intracranial SRS. Understand areas of ongoing work to standardize intracranial SRS and spine SBRT procedures. Schlesinger: Research support: Elekta Instruments, AB; D. Schlesinger, Elekta Instruments, AB - research support; B. Winey, No relevant external funding for this subject.

Assessment of SRS radiological liquid and airborne contaminants and pathways

International Nuclear Information System (INIS)

Jannik, G.T.

1997-04-01

This report compiles and documents the radiological critical-contaminant/critical-pathway analysis performed for SRS. The analysis covers radiological releases to the atmosphere and to surface water, which are the principal media that carry contaminants off site. During routine operations at SRS, limited amounts of radionuclides are released to the environment through atmospheric and/or liquid pathways. These releases potentially result in exposure to offsite people. Though the groundwater beneath an estimated 5 to 10 percent of SRS has been contaminated by radionuclides, there is no evidence that groundwater contaminated with these constituents has migrated offsite (Arnett, 1996). Therefore, with the notable exception of radiological source terms originating from shallow surface water migration into site streams, onsite groundwater was not considered as a potential exposure pathway to offsite people

Literature review of the potential impact of glycolic acid on the technetium chemistry of srs tank waste

International Nuclear Information System (INIS)

Nash, Charles A.; McCabe, Daniel J.

2017-01-01

This document presents a literature study of the impact of glycolate on technetium chemistry in the Savannah River Site (SRS) waste system and specifically Saltstone. A predominant portion of the Tc at SRS will be sent to the Saltstone Facility where it will be immobilized. The Tc in the tank waste is in the highly soluble chemical form of pertechnetate ion (TcO 4 - ) which is reduced by blast furnace slag (BFS) in Saltstone, rendering it highly insoluble and resistant to leaching.

Enterprise SRS: Leveraging Ongoing Operations to Advance National Programs - 13108

International Nuclear Information System (INIS)

Marra, J.E.; Murray, A.M.; McGuire, P.W.; Wheeler, V.B.

2013-01-01

The SRS is re-purposing its vast array of assets to solve future national issues regarding environmental stewardship, national security, and clean energy. The vehicle for this transformation is Enterprise SRS which presents a new, strategic view of SRS as a united endeavor for 'all things nuclear' as opposed to a group of distinct and separate entities with individual missions and organizations. Key among the Enterprise SRS strategic initiatives is the integration of research into facilities in conjunction with ongoing missions to provide researchers from other national laboratories, academic institutions, and commercial entities the opportunity to demonstrate their technologies in a relevant environment and scale prior to deployment. To manage that integration of research demonstrations into site facilities, The DOE Savannah River Operations Office, Savannah River Nuclear Solutions, and the Savannah River National Laboratory (SRNL) have established the Center for Applied Nuclear Materials Processing and Engineering Research (CANMPER). The key objective of this initiative is to bridge the gap between promising transformational nuclear materials management advancements and large-scale deployment of the technology by leveraging SRS assets (e.g. facilities, staff, and property) for those critical engineering-scale demonstrations necessary to assure the successful deployment of new technologies. CANMPER will coordinate the demonstration of R and D technologies and serve as the interface between the engineering-scale demonstration and the R and D programs, essentially providing cradle-to-grave support to the R and D team during the demonstration. While the initial focus of CANMPER will be on the effective use of SRS assets for these demonstrations, CANMPER also will work with research teams to identify opportunities to perform R and D demonstrations at other facilities. Unique to this approach is the fact that these SRS assets will continue to accomplish DOE's critical

Development of SRS.php, a Simple Object Access Protocol-based library for data acquisition from integrated biological databases.

Science.gov (United States)

Barbosa-Silva, A; Pafilis, E; Ortega, J M; Schneider, R

2007-12-11

Data integration has become an important task for biological database providers. The current model for data exchange among different sources simplifies the manner that distinct information is accessed by users. The evolution of data representation from HTML to XML enabled programs, instead of humans, to interact with biological databases. We present here SRS.php, a PHP library that can interact with the data integration Sequence Retrieval System (SRS). The library has been written using SOAP definitions, and permits the programmatic communication through webservices with the SRS. The interactions are possible by invoking the methods described in WSDL by exchanging XML messages. The current functions available in the library have been built to access specific data stored in any of the 90 different databases (such as UNIPROT, KEGG and GO) using the same query syntax format. The inclusion of the described functions in the source of scripts written in PHP enables them as webservice clients to the SRS server. The functions permit one to query the whole content of any SRS database, to list specific records in these databases, to get specific fields from the records, and to link any record among any pair of linked databases. The case study presented exemplifies the library usage to retrieve information regarding registries of a Plant Defense Mechanisms database. The Plant Defense Mechanisms database is currently being developed, and the proposal of SRS.php library usage is to enable the data acquisition for the further warehousing tasks related to its setup and maintenance.

Literature review of the potential impact of glycolic acid on the technetium chemistry of srs tank waste

Energy Technology Data Exchange (ETDEWEB)

Nash, Charles A. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); McCabe, Daniel J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2017-10-09

This document presents a literature study of the impact of glycolate on technetium chemistry in the Savannah River Site (SRS) waste system and specifically Saltstone. A predominant portion of the Tc at SRS will be sent to the Saltstone Facility where it will be immobilized. The Tc in the tank waste is in the highly soluble chemical form of pertechnetate ion (TcO₄ ^-) which is reduced by blast furnace slag (BFS) in Saltstone, rendering it highly insoluble and resistant to leaching.

Enterprise SRS: leveraging ongoing operations to advance radioactive waste management technologies

International Nuclear Information System (INIS)

Murray, Alice M.; Wilmarth, William; Marra, John E.

2013-01-01

The Savannah River Site (SRS) is re-purposing its vast array of assets to solve future national issues regarding environmental stewardship, national security, and clean energy. The vehicle for this transformation is Enterprise SRS which presents a new, strategic view of SRS as a united endeavor for 'all things nuclear' as opposed to a group of distinct and separate entities with individual missions and organizations. Key among the Enterprise SRS strategic initiatives is the integration of research into facilities in conjunction with ongoing missions to provide researchers from other national laboratories, academic institutions, and commercial entities the opportunity to demonstrate their technologies in a relevant environment and scale prior to deployment. To manage that integration of research demonstrations into site facilities, The DOE Savannah River Operations Office, Savannah River Nuclear Solutions, and the Savannah River National Laboratory (SRNL) have established a center for applied nuclear materials processing and engineering research (hereafter referred to as the Center). The key objective of this initiative is to bridge the gap between promising transformational nuclear materials management advancements and large-scale deployment of the technology by using SRS assets (e.g. facilities, staff, and property) for those critical engineering-scale demonstrations necessary to assure the successful deployment of new technologies. The Center will coordinate the demonstration of R and D technologies and serve as the interface between the engineering-scale demonstration and the R and D programs, essentially providing cradle-to-grave support to the R and D team during the demonstration. While the initial focus of the Center will be on the effective use of SRS assets for these demonstrations, the Center also will work with research teams to identify opportunities to perform R and D demonstrations at other facilities. Unique to this approach is the fact

Measurement of dosimetric parameters and dose verification in stereotactic radiosurgery (SRS)

International Nuclear Information System (INIS)

Reduan Abdullah; Nik Ruzman Nik Idris; Ahmad Lutfi Yusof; Mazurawati Mohamed

2013-01-01

Full-text: The purpose of this study was to measure the dosimetric parameters for small photon beams to be used as input data treatment planning computer system (TPS) and to verify dose calculated by TPS in Stereotactic Radiosurgery (SRS) procedure. The beam data required were Percentage Depth Dose (PDD), Off-axis Ratio (OAR), and Scatter Factor of Relative Output Factor. Small beams of 5 mm to 45 mm diameter circular cone collimators used in SRS were utilized for beam data measurements measured using pinpoint 3D ionization chamber (0.016 cc). For second part of this study, we reported the important quality assurance (QA) procedures before SRS treatment that influenced the dose delivery. These QA procedures consist of measurements on the accuracy in target localization and room laser alignment. The dose calculated to be delivered for treatment was verified using pinpoint 3D ionization chamber and TLD 100H. The mean deviation of measured dose using TLD 100H compared to calculated dose was 3.37 %. Beside that, pinpoint ionization 3D chamber give more accurate results of dose compared to TLD 100H. The measured dose using pinpoint 3D ionization chamber are good agreement with calculated dose by TPS with deviation of 2.17 %. The results are acceptable such as recommended by International Commission on Radiation Units and Measurements (ICRU) Report No. 50 (1993) that dose delivered to the target volume must be within ±5 % error. (author)

Comparison of indirect ELISA based on recombinant protein NcSRS2 and IFAT for detection of Neospora caninum antibodies in sheep Comparação entre ELISA baseado no antígeno recombinante NcSRS2 e RIFI para detecção de anticorpos de Neospora caninum em ovinos

Directory of Open Access Journals (Sweden)

Renato Andreotti

2009-06-01

Full Text Available Neospora caninum, an Apicomplexan parasite that can causes abortion, is responsible for considerable economic and reproductive losses in livestock. The purpose of the present study was to determine whether recombinant NcSRS2 is a suitable indirect ELISA antigen for determining specific immune response to N. caninum in sheep. A total of 441 serum samples were subjected to IFAT and rNcSRS2 based-ELISA, with both tests performing similarly. The sensitivity and specificity of indirect ELISA were 98.6 and 98.3%, respectively. The kappa index shows 0.98 concordance between the two tests, which is considered excellent. Seroprevalences of 30.8 and 32.0% were detected by IFAT and indirect ELISA, respectively, showing these tests did not differ significantly on this measure (p > 0.05. Serological analysis showed that HisG tag was detected by Western Blotting recognizing rNcSRS2 protein. The potential value of rNcSRS2-based ELISA as a highly specific and sensitive tool for serological diagnosis is also supported by the strong agreement found between IFAT and ELISA. The results support the potential use of recombinant protein NcSRS2 as an antigen in indirect ELISA in sheep.Neospora caninum é um parasito Apicomplexa que pode causar abortos e é reconhecido como agente importante responsável por perdas econômicas e reprodutivas. Este estudo avaliou a proteína recombinante NcSRS2 como antígeno para ELISA indireto na determinação de resposta imune para N. caninum em ovinos. 441 amostras de soro foram analisadas por IFAT e ELISA indireto com rNcSRS2 e ambos os testes revelaram comportamento similar. A sensibilidade e especificidade de ELISA indireto foram 98,6 e 98,3%, respectivamente. O índice kappa mostrou uma concordância entre os dois testes com valor de 0,98, que é considerado excelente. Prevalências de 30,8 e 32,0% detectadas por IFAT e ELISA indireto, respectivamente, mostraram que os testes não diferiram significativamente nesse aspecto (P

SRS Geology/Hydrogeology Environmental Information Document

International Nuclear Information System (INIS)

Denham, M.E.

1999-01-01

The purpose of the Savannah River Site Geology and Hydrogeology Environmental Information Document (EID) is to provide geologic and hydrogeologic information to serve as a baseline to evaluate potential environmental impacts. This EID is based on a summary of knowledge accumulated from research conducted at the Savannah River Site (SRS) and surrounding areas

SRS Geology/Hydrogeology Environmental Information Document

Energy Technology Data Exchange (ETDEWEB)

Denham, M.E.

1999-08-31

The purpose of the Savannah River Site Geology and Hydrogeology Environmental Information Document (EID) is to provide geologic and hydrogeologic information to serve as a baseline to evaluate potential environmental impacts. This EID is based on a summary of knowledge accumulated from research conducted at the Savannah River Site (SRS) and surrounding areas.

Modulation of the formation and release of bovine SRS-A in vitro by several anti-anaphylactic drugs.

Science.gov (United States)

Burka, J F; Eyre, P

1975-01-01

Slow-reacting substance of anaphylaxis (SRS-A) is released immunologically from bovine lung in vitro. Various drugs known to protect calves and other animals during anaphylaxis were tested to investigate their modulation of the formation and release of SRS-A. The anti-inflammatory drugs, meclofenamate and aspirin, potentiated SRS-A release. Chlorphenesin and diethylcarbamazine citrate at high concentrations both inhibited SRS-A release. Two new anti-anaphylactic drugs, PR-D-92-EA and M&B 22,948, were particularly effective in inhibiting SRS-A release at low concentrations. The possible modes of actions of these drugs are discussed.

SU-F-T-647: Linac-Based Stereotactic Radiosurgery (SRS) in the Treatment of Trigeminal Neuralgia: Detailed Description of SRS Procedural Technique and Reported Clinical Outcomes

Energy Technology Data Exchange (ETDEWEB)

Pokhrel, D; Sood, S; Badkul, R; Jiang, H; Stepp, T; Camarata, P; Wang, F [University of Kansas Hospital, Kansas City, KS (United States)

2016-06-15

Purpose: SRS is an effective non-invasive alternative treatment modality with minimal-toxicity used to treat patients with medically/surgically refractory trigeminal neuralgia root(TNR) or those who may not tolerate surgical intervention. We present our linac-based SRS procedure for TNR treatment and simultaneously report our clinical outcomes. Methods: Twenty-eight TNR-patients treated with frame-based SRS at our institution (2009–2015) with a single-fraction point-dose of 60-80Gy to TNR were included in this IRB-approved study. Experienced neurosurgeon and radiation oncologist delineated the TNR on 1.0mm thin 3D-FIESTA-MRI that was co-registered with 0.7mm thin planning-CT. Treatment plans were generated in iPlan (BrainLAB) with a 4-mm diameter cone using 79 arcs with differential-weighting for Novalis-TX 6MV-SRS(1000MU/min) beam and optimized to minimize brainstem dose. Winston-Lutz test was performed before each treatment delivery with sub-millimeter isocenter accuracy. Quality assurance of frame placement was maintained by helmet-bobble-measurement before simulation-CT and before patient setup at treatment couch. OBI-CBCT scan was performed for patient setup verification without applying shifts. On clinical follow up, treatment response was assessed using Barrow Neurological Institute Pain Intensity Score(BNI-score:I–V). Results: 26/28 TNR-patients (16-males/10-females) who were treated with following single-fraction point-dose to isocenter: 80Gy(n=22),75Gy(n=1),70Gy(n=2) and 60Gy(n=1, re-treatment) were followed up. Median follow-up interval was 8.5-months (ranged:1–48.5months). Median age was 70-yr (ranged:43–93-yr). Right/left TNR ratio was 15/11. Delivered total # of average MUs was 19034±1204. Average beam-on-time: 19.0±1.3min. Brainstem max-dose and dose to 0.5cc were 13.3±2.4Gy (ranged:8.1–16.5Gy) and 3.6±0.4Gy (ranged:3.0–4.9Gy). On average, max-dose to optic-apparatus was ≤1.2Gy. Mean value of max-dose to eyes/lens was 0.26Gy/0.11Gy

SRS Burial Ground Complex: Remediation in Progress

International Nuclear Information System (INIS)

Griffin, M.; Crapse, B.; Cowan, S.

1998-01-01

Closure of the various areas in the Burial Ground Complex (BGC) represents a major step in the reduction of risk at the Savannah River Site (SRS) and a significant investment of resources. The Burial Ground Complex occupies approximately 195 acres in the central section of the SRS. Approximately 160 acres of the BGC consists of hazardous and radioactive waste disposal sites that require remediation. Of these source acres, one-third have been remediated while two-thirds are undergoing interim or final action. These restoration activities have been carried out in a safe and cost effective manner while minimizing impact to operating facilities. Successful completion of these activities is in large part due to the teamwork demonstrated by the Department of Energy, contractor/subcontractor personnel, and the regulatory agencies. The experience and knowledge gained from the closure of these large disposal facilities can be used to expedite closure of similar facilities

Physiological and Comparative Genomic Analysis of Arthrobacter sp. SRS-W-1-2016 Provides Insights on Niche Adaptation for Survival in Uraniferous Soils

Directory of Open Access Journals (Sweden)

Ashvini Chauhan

2018-01-01

, peptide/nickel transport substrate and ATP-binding proteins, a high-affinity nickel-transport protein, and the spoT gene, which was recently implicated in bacterial resistance towards U. Detailed genome mining analysis of strain SRS-W-1-2016 also revealed the presence of a plethora of secondary metabolite biosynthetic gene clusters likely facilitating resistance to antibiotics, biocides, and metals. Additionally, several gene homologous for the well-known oxygenase enzyme system were also identified, potentially functioning to generate energy via the breakdown of organic compounds and thus enabling the successful colonization and natural attenuation of contaminants by Arthrobacter sp. SRS-W-1-2016 at the SRS site.

Physiological and Comparative Genomic Analysis of Arthrobacter sp. SRS-W-1-2016 Provides Insights on Niche Adaptation for Survival in Uraniferous Soils.

Science.gov (United States)

Chauhan, Ashvini; Pathak, Ashish; Jaswal, Rajneesh; Edwards, Bobby; Chappell, Demario; Ball, Christopher; Garcia-Sillas, Reyna; Stothard, Paul; Seaman, John

2018-01-11

/nickel transport substrate and ATP-binding proteins, a high-affinity nickel-transport protein, and the spoT gene, which was recently implicated in bacterial resistance towards U. Detailed genome mining analysis of strain SRS-W-1-2016 also revealed the presence of a plethora of secondary metabolite biosynthetic gene clusters likely facilitating resistance to antibiotics, biocides, and metals. Additionally, several gene homologous for the well-known oxygenase enzyme system were also identified, potentially functioning to generate energy via the breakdown of organic compounds and thus enabling the successful colonization and natural attenuation of contaminants by Arthrobacter sp. SRS-W-1-2016 at the SRS site.

SRS BEDROCK PROBABILISTIC SEISMIC HAZARD ANALYSIS (PSHA) DESIGN BASIS JUSTIFICATION (U)

Energy Technology Data Exchange (ETDEWEB)

(NOEMAIL), R

2005-12-14

This represents an assessment of the available Savannah River Site (SRS) hard-rock probabilistic seismic hazard assessments (PSHAs), including PSHAs recently completed, for incorporation in the SRS seismic hazard update. The prior assessment of the SRS seismic design basis (WSRC, 1997) incorporated the results from two PSHAs that were published in 1988 and 1993. Because of the vintage of these studies, an assessment is necessary to establish the value of these PSHAs considering more recently collected data affecting seismic hazards and the availability of more recent PSHAs. This task is consistent with the Department of Energy (DOE) order, DOE O 420.1B and DOE guidance document DOE G 420.1-2. Following DOE guidance, the National Map Hazard was reviewed and incorporated in this assessment. In addition to the National Map hazard, alternative ground motion attenuation models (GMAMs) are used with the National Map source model to produce alternate hazard assessments for the SRS. These hazard assessments are the basis for the updated hard-rock hazard recommendation made in this report. The development and comparison of hazard based on the National Map models and PSHAs completed using alternate GMAMs provides increased confidence in this hazard recommendation. The alternate GMAMs are the EPRI (2004), USGS (2002) and a regional specific model (Silva et al., 2004). Weights of 0.6, 0.3 and 0.1 are recommended for EPRI (2004), USGS (2002) and Silva et al. (2004) respectively. This weighting gives cluster weights of .39, .29, .15, .17 for the 1-corner, 2-corner, hybrid, and Greens-function models, respectively. This assessment is judged to be conservative as compared to WSRC (1997) and incorporates the range of prevailing expert opinion pertinent to the development of seismic hazard at the SRS. The corresponding SRS hard-rock uniform hazard spectra are greater than the design spectra developed in WSRC (1997) that were based on the LLNL (1993) and EPRI (1988) PSHAs. The

An assessment of underground and aboveground steam system failures in the SRS waste tank farms

International Nuclear Information System (INIS)

Hsu, T.C.; Shurrab, M.S.; Wiersma, B.J.

1997-01-01

Underground steam system failures in waste tank farms at the Savannah River Site (SRS) increased significantly in the 3--4 year period prior to 1995. The primary safety issues created by the failures were the formation of sub-surface voids in soil and the loss of steam jet transfer and waste evaporation capability, and the loss of heating and ventilation to the tanks. The average annual cost for excavation and repair of the underground steam system was estimated to be several million dollars. These factors prompted engineering personnel to re-consider long-term solutions to the problem. The primary cause of these failures was the inadequate thermal insulation utilized for steam lines associated with older tanks. The failure mechanisms were either pitting or localized general corrosion on the exterior of the pipe beneath the thermal insulation. The most realistic and practical solution is to replace the underground lines by installing aboveground steam systems, although this option will incur significant initial capital costs. Steam system components, installed aboveground in other areas of the tank farms have experienced few failures, while in continuous use. As a result, piecewise installation of temporary aboveground steam systems have been implemented in F-area whenever opportunities, i.e., failures, present themselves

Do the SRS-22 self-image and mental health domain scores reflect the degree of asymmetry of the back in adolescent idiopathic scoliosis?

Science.gov (United States)

Cheshire, James; Gardner, Adrian; Berryman, Fiona; Pynsent, Paul

2017-01-01

Patient-reported outcomes are becoming increasingly recognised in the management of patients with adolescent idiopathic scoliosis (AIS). Integrated Shape Imaging System 2 (ISIS2) surface topography is a validated tool to assess AIS. Previous studies have failed to demonstrate strong correlations between AIS and patient-reported outcomes highlighting the need for additional objective surface parameters to define the deformities associated with AIS. The aim of this study was to examine whether the Scoliosis Research Society-22 (SRS-22) outcome questionnaire reflects the degree of measurable external asymmetry of the back in AIS and thus is a measure of patient outcome for external appearance. A total of 102 pre-operative AIS patients were identified retrospectively. Objective parameters were measured using ISIS2 surface topography. The associations between these parameters and the self-image and mental health domains of the SRS-22 questionnaire were investigated using correlation coefficients. All correlations between the parameters of asymmetry and SRS-22 self-image score were of weak strength. Similarly, all correlations between the parameters of asymmetry and SRS-22 mental health score were of weak strength. The SRS-22 mental health and self-image domains correlate poorly with external measures of deformity. This demonstrates that the assessment of mental health and self-image by the SRS-22 has little to do with external torso shape. Whilst the SRS-22 assesses the patient as a whole, it provides little information about objective measures of deformity over which a surgeon has control.

Maxdose-SR and popdose-SR routine release atmospheric dose models used at SRS

Energy Technology Data Exchange (ETDEWEB)

Jannik, G. T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Trimor, P. P. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2017-07-28

MAXDOSE-SR and POPDOSE-SR are used to calculate dose to the offsite Reference Person and to the surrounding Savannah River Site (SRS) population respectively following routine releases of atmospheric radioactivity. These models are currently accessed through the Dose Model Version 2014 graphical user interface (GUI). MAXDOSE-SR and POPDOSE-SR are personal computer (PC) versions of MAXIGASP and POPGASP, which both resided on the SRS IBM Mainframe. These two codes follow U.S. Nuclear Regulatory Commission (USNRC) Regulatory Guides 1.109 and 1.111 (1977a, 1977b). The basis for MAXDOSE-SR and POPDOSE-SR are USNRC developed codes XOQDOQ (Sagendorf et. al 1982) and GASPAR (Eckerman et. al 1980). Both of these codes have previously been verified for use at SRS (Simpkins 1999 and 2000). The revisions incorporated into MAXDOSE-SR and POPDOSE-SR Version 2014 (hereafter referred to as MAXDOSE-SR and POPDOSE-SR unless otherwise noted) were made per Computer Program Modification Tracker (CPMT) number Q-CMT-A-00016 (Appendix D). Version 2014 was verified for use at SRS in Dixon (2014).

Yeast Srs2 Helicase Promotes Redistribution of Single-Stranded DNA-Bound RPA and Rad52 in Homologous Recombination Regulation

Directory of Open Access Journals (Sweden)

Luisina De Tullio

2017-10-01

Full Text Available Srs2 is a super-family 1 helicase that promotes genome stability by dismantling toxic DNA recombination intermediates. However, the mechanisms by which Srs2 remodels or resolves recombination intermediates remain poorly understood. Here, single-molecule imaging is used to visualize Srs2 in real time as it acts on single-stranded DNA (ssDNA bound by protein factors that function in recombination. We demonstrate that Srs2 is highly processive and translocates rapidly (∼170 nt per second in the 3′→5′ direction along ssDNA saturated with replication protein A (RPA. We show that RPA is evicted from DNA during the passage of Srs2. Remarkably, Srs2 also readily removes the recombination mediator Rad52 from RPA-ssDNA and, in doing so, promotes rapid redistribution of both Rad52 and RPA. These findings have important mechanistic implications for understanding how Srs2 and related nucleic acid motor proteins resolve potentially pathogenic nucleoprotein intermediates.

Methodology of dose calculation for the SRS SAR

International Nuclear Information System (INIS)

Price, J.B.

1991-07-01

The Savannah River Site (SRS) Safety Analysis Report (SAR) covering K reactor operation assesses a spectrum of design basis accidents. The assessment includes estimation of the dose consequences from the analyzed accidents. This report discusses the methodology used to perform the dose analysis reported in the SAR and also includes the quantified doses. Doses resulting from postulated design basis reactor accidents in Chapter 15 of the SAR are discussed, as well as an accident in which three percent of the fuel melts. Doses are reported for both atmospheric and aqueous releases. The methodology used to calculate doses from these accidents as reported in the SAR is consistent with NRC guidelines and industry standards. The doses from the design basis accidents for the SRS reactors are below the limits set for commercial reactors by the NRC and also meet industry criteria. A summary of doses for various postulated accidents is provided

The comparison of SRs' variation affected by solar events observed in America and in China

Science.gov (United States)

Yu, H.; Williams, E.

2017-12-01

Schumann Resonances(SRs) are the electromagnetic resonance wave propagating in the earth-ionosphere cavity. Its characteristic of propagation are modified by the variation of ionosphere. So SRs can be the tools of monitoring the ionosphere which is often perturbed by solar events, x-ray emission and some other space-weather events (Roldugin et.al., 2004, De et al., 2010; Satori et.al., 2015). In present work, the amplitude and intrinsic frequencies of SRs observed at RID station in America and YSH station in China are compared. The variation of SRs during the solar flare on Feb. 15, 2011 are analyzed. Two-Dimensional Telegraph Equation(TDTE) method is used to simulate the perturbation of ionosphere by solar proton events. From the simulation and observation, the asymmetric construction of ionoshphere which is perturbed by the solar event will affect the amplitudes and frequencies of SRs. Due to the interfere influence of forward and backward propagation of electromagnetic field, the SR amplitude on different station will present different variation. The distance among the lightning source, observer and perturbed area will produce the different variation of amplitude and frequency for different station' SR.

Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo

DEFF Research Database (Denmark)

Burgess, Rebecca C; Lisby, Michael; Altmannova, Veronika

2009-01-01

, and surprisingly, can form in the absence of Rad52 mediation. However, these Rad51 foci do not represent repair-proficient filaments, as determined by recombination assays. Antagonistic roles for Rad52 and Srs2 in Rad51 filament formation are also observed in vitro. Furthermore, we provide evidence that Srs2......Homologous recombination (HR), although an important DNA repair mechanism, is dangerous to the cell if improperly regulated. The Srs2 "anti-recombinase" restricts HR by disassembling the Rad51 nucleoprotein filament, an intermediate preceding the exchange of homologous DNA strands. Here, we...... removes Rad51 indiscriminately from DNA, while the Rad52 protein coordinates appropriate filament reformation. This constant breakdown and rebuilding of filaments may act as a stringent quality control mechanism during HR....

Pilot study risk assessment for selected problems at the Savannah River Site (SRS)

International Nuclear Information System (INIS)

Hamilton, L.D.; Holtzman, S.; Meinhold, A.; Morris, S.C.; Pardi, R.; Sun, C.; Daniels, J.I.; Layton, D.; McKone, T.E.; Straume, T.; Anspaugh, L.

1993-03-01

An assessment of the health risks was made for releases of tritium and 137 Cs from the Savannah River Site (SRS) at water-receptor locations downriver. Although reactor operations were shut down at the SRS in 1989, liquid wastes continue to be released to the Savannah River either by direct discharges into onsite surface waters or by groundwater transport into surface waters from waste facilities. Existing state mandates will cause the liquid waste streams from future operations to go directly into surface waters. Two drinking water processing plants take water from the river approximately 129 km downriver from the SRS. Potential incremental risks of cancer fatality to individuals and each population were analyzed for either no further reactor operations or resumption of operation of one specific reactor

SRS stainless steel beneficial reuse program

Energy Technology Data Exchange (ETDEWEB)

Boettinger, W.L.

1997-02-01

The US Department of Energy`s (DOE) Savannah River Site (SRS) has thousands of tons of stainless steel radioactive scrap metal (RSNI). Much of the metal is volumetrically contaminated. There is no {open_quotes}de minimis{close_quotes} free release level for volumetric material, and therefore no way to recycle the metal into the normal commercial market. If declared waste, the metal would qualify as low level radioactive waste (LLW) and ultimately be dispositioned through shallow land buried at a cost of millions of dollars. The metal however could be recycled in a {open_quotes}controlled release{close_quote} manner, in the form of containers to hold other types of radioactive waste. This form of recycle is generally referred to as {open_quotes}Beneficial Reuse{close_quotes}. Beneficial reuse reduces the amount of disposal space needed and reduces the need for virgin containers which would themselves become contaminated. Stainless steel is particularly suited for long term storage because of its resistance to corrosion. To assess the practicality of stainless steel RSM recycle the SRS Benficial Reuse Program began a demonstration in 1994, funded by the DOE Office of Science and Technology. This paper discusses the experiences gained in this program.

Yeast Srs2 Helicase Promotes Redistribution of Single-Stranded DNA-Bound RPA and Rad52 in Homologous Recombination Regulation.

Science.gov (United States)

De Tullio, Luisina; Kaniecki, Kyle; Kwon, Youngho; Crickard, J Brooks; Sung, Patrick; Greene, Eric C

2017-10-17

Srs2 is a super-family 1 helicase that promotes genome stability by dismantling toxic DNA recombination intermediates. However, the mechanisms by which Srs2 remodels or resolves recombination intermediates remain poorly understood. Here, single-molecule imaging is used to visualize Srs2 in real time as it acts on single-stranded DNA (ssDNA) bound by protein factors that function in recombination. We demonstrate that Srs2 is highly processive and translocates rapidly (∼170 nt per second) in the 3'→5' direction along ssDNA saturated with replication protein A (RPA). We show that RPA is evicted from DNA during the passage of Srs2. Remarkably, Srs2 also readily removes the recombination mediator Rad52 from RPA-ssDNA and, in doing so, promotes rapid redistribution of both Rad52 and RPA. These findings have important mechanistic implications for understanding how Srs2 and related nucleic acid motor proteins resolve potentially pathogenic nucleoprotein intermediates. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

High-power SRS lasers – coherent summators (the way it was)

International Nuclear Information System (INIS)

Grasiuk, Arkadii Z; Zubarev, I G; Efimkov, V F; Smirnov, V G

2012-01-01

The history of the research works performed under the guidance of H.G. Basov and aimed at developing high-energy lasers – coherent summators (CSs) – based on stimulated Raman scattering (SRS) in liquid nitrogen and liquid oxygen is reported. The work was performed jointly by researchers of FIAN [the Laboratory of Quantum Radiophysics (LQRP)] and VNIIEF. Many problems were solved as a result of these studies. Liquid nitrogen and oxygen were found to be optimal active media for high-power SRS lasers with high energy per pulse. A method for purifying these cryogenic liquids from micro- and nanoimpurities was developed, which made it possible to eliminate nonlinear loss of pump radiation and converted radiation in the active medium and ensure effective operation of SRS lasers – coherent summators (SRSL CSs) with high output energy. Cryogenic cells providing high optical homogeneity of liquid nitrogen and oxygen were developed, which ensured low (at a level of 0.1 mrad) divergence of converted radiation with high energy density. Raster focusing systems providing optimal concentration of pump radiation in the active medium were designed. These studies resulted in the development of high-power highenergy SRSL CSs with a low beam divergence, based on liquid nitrogen (λ S = 1.89 μm) and liquid oxygen (λ S = 1.65 μm), with pumping by explosively pumped iodine lasers (EPILs) (λ p = 1.315 μm). The characteristics of the SRSL CSs developed were record for that time (the end of 1960s and the beginning of 1970s): energy up to 2.5 kJ per 10-μs pulse, beam divergence ∼10 -4 rad, and beam energy density of several hundreds of J cm -2 . (special issue devoted to the 90th anniversary of n.g. basov)

Conservatism in SRS Criticality Alarm System 12 Rad Zone Calculations - How Much is Enough?

International Nuclear Information System (INIS)

Yates, K.R.

2002-01-01

Savannah River Site (SRS) uses two methods (i.e., Approximate Method and MCNP) of calculating the 12-rad zone. The reasons for the two-tier approach are described in Ref. 1 and 2. Lately, there have been occasions in which the use of either the Approximate Method (AM) or MCNP3 calculations indicated potential facility impacts. For example, one or both methods may indicate that a 12-rad zone extends outside of relatively thick shielding, or extends to the roof of a facility, or extends through shielding to part of a stairwell. In such cases, a criticality alarm system may have to be installed to protect workers in a small, localized area from a potential dose that is not substantially greater than 12 rad in air. But, is the potential dose really greater than 12 rad in air? A subcommittee was appointed to look into the two 12-rad zone calculation methods for the purpose of identifying items contributing to over-conservatism and under-conservatism, and to recommend a path forward

Pilot study risk assessment for selected problems at the Savannah River Site (SRS)

Energy Technology Data Exchange (ETDEWEB)

Hamilton, L.D.; Holtzman, S.; Meinhold, A.; Morris, S.C.; Pardi, R.; Sun, C. [Brookhaven National Lab., Upton, NY (United States); Daniels, J.I.; Layton, D.; McKone, T.E.; Straume, T.; Anspaugh, L. [Lawrence Livermore National Lab., CA (United States)

1993-03-01

An assessment of the health risks was made for releases of tritium and {sup 137}Cs from the Savannah River Site (SRS) at water-receptor locations downriver. Although reactor operations were shut down at the SRS in 1989, liquid wastes continue to be released to the Savannah River either by direct discharges into onsite surface waters or by groundwater transport into surface waters from waste facilities. Existing state mandates will cause the liquid waste streams from future operations to go directly into surface waters. Two drinking water processing plants take water from the river approximately 129 km downriver from the SRS. Potential incremental risks of cancer fatality to individuals and each population were analyzed for either no further reactor operations or resumption of operation of one specific reactor.

Pilot study risk assessment for selected problems at the Savannah River Site (SRS)

Energy Technology Data Exchange (ETDEWEB)

Hamilton, L.D.; Holtzman, S.; Meinhold, A.; Morris, S.C.; Pardi, R.; Sun, C. (Brookhaven National Lab., Upton, NY (United States)); Daniels, J.I.; Layton, D.; McKone, T.E.; Straume, T.; Anspaugh, L. (Lawrence Livermore National Lab., CA (United States))

1993-03-01

An assessment of the health risks was made for releases of tritium and [sup 137]Cs from the Savannah River Site (SRS) at water-receptor locations downriver. Although reactor operations were shut down at the SRS in 1989, liquid wastes continue to be released to the Savannah River either by direct discharges into onsite surface waters or by groundwater transport into surface waters from waste facilities. Existing state mandates will cause the liquid waste streams from future operations to go directly into surface waters. Two drinking water processing plants take water from the river approximately 129 km downriver from the SRS. Potential incremental risks of cancer fatality to individuals and each population were analyzed for either no further reactor operations or resumption of operation of one specific reactor.

Postoperative Perfection: Ceiling Effects and Lack of Discrimination With Both SRS-22 and -24 Outcomes Instruments in Patients With Adolescent Idiopathic Scoliosis.

Science.gov (United States)

Bastrom, Tracey P; Bartley, Carrie; Marks, Michelle C; Yaszay, Burt; Newton, Peter O

2015-12-01

Review of a prospective database registry. To compare the Scoliosis Research Society (SRS)-22 and SRS-24 outcomes instruments in terms of scores, rate of ceiling effects, and discriminant ability in patients with pre- and postoperative adolescent idiopathic scoliosis. Despite improvements noted with the SRS-22, the SRS-24 is still occasionally used prospectively and for comparisons with previous studies reporting SRS-24 scores. Previous work has demonstrated that postoperative scores from the 2 versions are not interchangeable. A multicenter prospective registry of patients who underwent surgical correction of adolescent idiopathic scoliosis was queried for preoperative and 2-year postoperative SRS-22 and SRS-24 scores. Scores were compared between versions and ceiling effects were identified. Groups of deformity severity were created to evaluate discriminant ability. 829 patients were identified. The SRS-22 scores for pain and general function were significantly greater than SRS-24 scores (P self-image (P self-image domain was able to discriminate between large (29°+) and small (≤11°) residual curves (P < 0.05). Scores obtained by the SRS-22 and the SRS-24 are not translatable despite shared domains. Whereas both versions demonstrated preoperative discriminant ability, postoperative discrimination of residual deformity is lacking in both. Patient-reported outcomes of treatment are crucial in advancing treatment, and improvement in the ability to assess subjective outcomes is essential. 3.

Validade concorrente da versão Brasileira do SRS-22r com o Br-SF-36 Concurrent validity of the Brazilian version of SRS-22r with Br-SF-36

Directory of Open Access Journals (Sweden)

Giselle C. L. Rosanova

2010-04-01

Full Text Available CONTEXTUALIZAÇÃO: A validade concorrente, relevante na adaptação transcultural, refere-se à relação entre o desempenho do instrumento de interesse e o desempenho de instrumento semelhante com validade conhecida. OBJETIVO: Realizar a validação concorrente da versão brasileira do questionário revisado da Scoliosis Research Society (Br-SRS-22r com a versão brasileira do Short Form-36 (Br-SF-36. MÉTODOS: Foram selecionados 54 pacientes com escoliose idiopática com média de 19,9 anos (±7,7 e curvaturas com média de 31,6° (±20,5° graus Cobb, variando entre 10º e 92º. Os questionários tiveram seus resultados convertidos em escores, e a análise estatística correlacionou os domínios concorrentes utilizando o cálculo de coeficiente de Spearman. RESULTADOS: Os domínios de melhor correlação foram função do Br-SRS-22r com função física do Br-SF-36 (r=0,83 e dor do Br-SRS-22r com dor do Br-SF-36 (r=0,86. Entretanto, os domínios autoimagem e satisfação com o tratamento do Br-SRS-22r apresentaram baixa correlação com seus domínios concorrentes do Br-SF-36. DISCUSSÃO: Houve uma correlação satisfatória entre os questionários, sendo que as melhores correlações indicam maior semelhança nos parâmetros avaliados entre os respectivos instrumentos. As melhores correlações foram as dos domínios função e dor, não ocorrendo em saúde mental, possivelmente devido às dificuldades de interpretação de suas questões no Br-SF-36. Para os domínios autoimagem e satisfação com o tratamento do Br-SRS-22r, a correlação é pouco satisfatória por não serem especificamente abordados pelo SF-36. CONCLUSÃO: A versão brasileira do SRS-22r apresentou resultados satisfatórios para a validação concorrente com o Br-SF-36, sendo considerada válida para a versão adaptada à cultura brasileira.BACKGROUND: An important parameter in cross-cultural adaptations, and concurrent validity are the relationships between the

Incidence of spinal deformity in adults and its distribution according SRS-Schwab classification

Directory of Open Access Journals (Sweden)

Marcus Vinicius Amaral Barreto

2015-06-01

Full Text Available OBJECTIVE: To evaluate the incidence of spinal deformity in adults, as well as its distribution according the curve type and the occurrence of sagittal modifiers of the SRS-Schwab classification..METHODS: Radiographs in frontal and lateral views of the entire column were performed and radiographic parameters were used to diagnose the vertebral deformity for the classification according to the SRS-Schwab system.RESULTS: We included 302 patients in the study, 236 (78.1% women and 66 (21.9% men. Fifty-six of the participants were diagnosed with ASD, 50 women and 6 men. The incidence of ASD was 18.5% in the total population, ranging from 9.1% in males and 21.2% in females (p=0.04. As to age group, the incidence was 11.9% in patients between 18 and 39 years, 12% between 40 and 59 years and 28.8% in patients with 60 years of age or older, significantly higher in the oldest group (p=0.002. When analyzing the correlation between age and progression of sagittal modifiers, there was no significant difference in the PI-LL and PT modifiers, but there was significant difference of SVA modifier (p=0.008, with a higher age in individuals "++".CONCLUSION: This study presented demographic data on ASD in a Brazilian population sample. There was a higher incidence of ASD in females and individuals aged ≥ 60 years. As for the sagittal modifiers of SRS-Schwab classification, there was a correlation between increasing age and degree of progression of SVA.

Enterprise SRS: Leveraging Ongoing Operations To Advance Nuclear Fuel Cycles Research And Development Programs

International Nuclear Information System (INIS)

Murray, Alice M.; Marra, John E.; Wilmarth, William R.; Mcguire, Patrick W.; Wheeler, Vickie B.

2013-01-01

The Savannah River Site (SRS) is repurposing its vast array of assets to solve future national issues regarding environmental stewardship, national security, and clean energy. The vehicle for this transformation is Enterprise SRS which presents a new, radical view of SRS as a united endeavor for ''all things nuclear'' as opposed to a group of distinct and separate entities with individual missions and organizations. Key among the Enterprise SRS strategic initiatives is the integration of research into facilities in conjunction with on-going missions to provide researchers from other national laboratories, academic institutions, and commercial entities the opportunity to demonstrate their technologies in a relevant environment and scale prior to deployment. To manage that integration of research demonstrations into site facilities, The Department of Energy, Savannah River Operations Office, Savannah River Nuclear Solutions, the Savannah River National Laboratory (SRNL) have established a center for applied nuclear materials processing and engineering research (hereafter referred to as the Center). The key proposition of this initiative is to bridge the gap between promising transformational nuclear fuel cycle processing discoveries and large commercial-scale-technology deployment by leveraging SRS assets as facilities for those critical engineering-scale demonstrations necessary to assure the successful deployment of new technologies. The Center will coordinate the demonstration of R&D technologies and serve as the interface between the engineering-scale demonstration and the R&D programs, essentially providing cradle-to-grave support to the research team during the demonstration. While the initial focus of the Center will be on the effective use of SRS assets for these demonstrations, the Center also will work with research teams to identify opportunities to perform research demonstrations at other facilities. Unique to this approach is the fact that these SRS

Development and validation of an item response theory-based Social Responsiveness Scale short form.

Science.gov (United States)

Sturm, Alexandra; Kuhfeld, Megan; Kasari, Connie; McCracken, James T

2017-09-01

Research and practice in autism spectrum disorder (ASD) rely on quantitative measures, such as the Social Responsiveness Scale (SRS), for characterization and diagnosis. Like many ASD diagnostic measures, SRS scores are influenced by factors unrelated to ASD core features. This study further interrogates the psychometric properties of the SRS using item response theory (IRT), and demonstrates a strategy to create a psychometrically sound short form by applying IRT results. Social Responsiveness Scale analyses were conducted on a large sample (N = 21,426) of youth from four ASD databases. Items were subjected to item factor analyses and evaluation of item bias by gender, age, expressive language level, behavior problems, and nonverbal IQ. Item selection based on item psychometric properties, DIF analyses, and substantive validity produced a reduced item SRS short form that was unidimensional in structure, highly reliable (α = .96), and free of gender, age, expressive language, behavior problems, and nonverbal IQ influence. The short form also showed strong relationships with established measures of autism symptom severity (ADOS, ADI-R, Vineland). Degree of association between all measures varied as a function of expressive language. Results identified specific SRS items that are more vulnerable to non-ASD-related traits. The resultant 16-item SRS short form may possess superior psychometric properties compared to the original scale and emerge as a more precise measure of ASD core symptom severity, facilitating research and practice. Future research using IRT is needed to further refine existing measures of autism symptomatology. © 2017 Association for Child and Adolescent Mental Health.

The influence of Savannah River discharge and changing SRS cooling water requirements on the potential entrainment of ichthyoplankton at the SRS Savannah River intakes

International Nuclear Information System (INIS)

Paller, M.H.

1992-08-01

Entrainment (i.e., withdrawal of fish larvae and eggs in cooling water) at the SRS Savannah River intakes is greatest when periods of high river water usage coincide with low river dischargeduring the spawning season. American shad and striped bass are the two species of greatest concern because of their recreational and/or commercial importance and because they produce drifting eggs and larvae vulnerable to entrainment. In the mid-reaches of the Savannah River, American shad and striped bass spawn primarily during April and May. An analysis of Savannah River discharge during April and May 1973--1989 indicated the potential for entrainment of 4--18% of the American shad and striped bass larvae and eggs that drifted past the SRS. This analysis assumed the concurrent operation of L-, K-, and P-Reactors. Additional scenarios investigated were: (1) shutting down L- and P-Reactors, and operating K-Reactor with a recycle cooling tower; and (2) shutting down L- and P-Reactors, eliminating minimum flows to Steel Creek, and operating K-Reactor with a recycle cooling tower. The former scenario reduced potential entrainment to 0.7--3.3%, and the latter scenario reduced potential entrainment to 0.20.8%. Thus, the currently favored scenario of operating K-Reactor with a cooling tower and not operating L- and P-Reactors represents a significant lessening of the impact of SRS operations

Ground motion following selection of SRS design basis earthquake and associated deterministic approach

International Nuclear Information System (INIS)

1991-03-01

This report summarizes the results of a deterministic assessment of earthquake ground motions at the Savannah River Site (SRS). The purpose of this study is to assist the Environmental Sciences Section of the Savannah River Laboratory in reevaluating the design basis earthquake (DBE) ground motion at SRS during approaches defined in Appendix A to 10 CFR Part 100. This work is in support of the Seismic Engineering Section's Seismic Qualification Program for reactor restart

Analyses of SRS waste glass buried in granite in Sweden and salt in the United States

International Nuclear Information System (INIS)

Williams, J.P.; Wicks, G.G.; Clark, D.E.; Lodding, A.R.

1991-01-01

Simulated Savannah River Site (SRS) waste glass forms have been buried in the granite geology of the Stirpa mine in Sweden for two years. Analyses of glass surfaces provided a measure of the performance of the waste glasses as a function of time. Similar SRS waste glass compositions have also been buried in salt at the WIPP facility in Carlsbad, New Mexico for a similar time period. Analyses of the SRS waste glasses buried in-situ in granite will be presented and compared to the performance of these same compositions buried in salt at WIPP

NONLINEAR OPTICAL PHENOMENA Intracavity SRS conversion in diode-pumpedmultifunctional Nd3+:SrMoO4 laser crystal

Science.gov (United States)

Basiev, Tasoltan T.; Smetanin, Sergei N.; Fedin, Aleksandr V.; Shurygin, Anton S.

2010-10-01

Lasing of a miniature all-solid-state SRS laser based on a Nd3+:SrMoO4 crystal with a LiF:F2--passive Q-switch is studied. The dependences of the laser and SRS self-conversion parameters on the initial transmission of the passive Q-switch are studied experimentally and theoretically. Simulation of the lasing kinetics has shown the possibility of nonlinear cavity dumping upon highly efficient SRS self-conversion of laser radiation. An increase in the active medium length from 1 to 3mm resulted in an increase in the energy of the output 1.17-μm SRS radiation from 20 μJ to record-high 60 μJ at the absorbed multimode diode pump energy of 3.7 mJ.

First Stabilization and Disposal of Radioactive Zinc Bromide at the SRS

International Nuclear Information System (INIS)

Denny, J.K.

2003-01-01

Facilities Disposition Projects (FDP) personnel at Savannah River Site (SRS) implement the Inactive Facility Risk Management Program to drive down risk and costs in SRS inactive facilities. The program includes cost-effective techniques to identify and dispose of hazardous chemicals and radioactive waste from inactive facilities, thereby ensuring adequate protection of the public, workers and the environment. In June 1998, FDP conducted an assessment of the inactive C-Reactor Facility to assure that chemical and radiological hazards had been identified and were being safely managed. The walkdown identified the need to mitigate a significant hazard associated with storing approximately 13,400 gallons of liquid radioactive Zinc Bromide in three aging railcar tankers outside of the facility. No preventive maintenance was being performed on the rusting tankers and a leak could send radioactive Zinc Bromide into an outfall and offsite to the Savannah River. In 2001, DOE-Savannah River (DOE- SR) funded the FDP to eliminate the identified hazard by disposing of the radioactive Zinc Bromide solution and the three contaminated railcar tankers. This paper describes the innovative, cost-effective approaches and technology used to perform the first stabilization and disposal of radioactive Zinc Bromide at SRS

Development of a Rotary Microfilter for SRS HLW Applications

International Nuclear Information System (INIS)

MICHAEL, POIRIER

2004-01-01

The processing rate of Savannah River Site high level waste decontamination processes are limited by the flow rate of the solid-liquid separation. The baseline process, using a 0.1 micron cross flow filter, produces 0.02 gpm/ft2 of filtrate under expected operating conditions. Savannah River National Laboratory personnel identified the rotary microfilter as a technology that could significantly increase filter flux, with throughput improvements of as much as 10X for that specific operation. With funding from the Department of Energy Office of Cleanup Technologies, SRNL personnel are evaluating and developing the rotary microfilter for radioactive service at SRS. This work includes pilot-scale and actual waste testing to evaluate system reliability, the impact of radiation on system components, the filter flux for a variety of waste streams, and relative performance for alternative filter media

A Comprehensive Analysis of the SRS-Schwab Adult Spinal Deformity Classification and Confounding Variables

DEFF Research Database (Denmark)

Hallager, Dennis Winge; Hansen, Lars Valentin; Dragsted, Casper Rokkjær

2016-01-01

STUDY DESIGN: Cross-sectional analyses on a consecutive, prospective cohort. OBJECTIVE: To evaluate the ability of the Scoliosis Research Society (SRS)-Schwab Adult Spinal Deformity Classification to group patients by widely used health-related quality-of-life (HRQOL) scores and examine possible...... to confounding. However, age group and aetiology had individual significant effects. CONCLUSION: The SRS-Schwab sagittal modifiers reliably grouped patients graded 0 versus + / +  + according to the most widely used HRQOL scores and the effects of increasing grade level on odds for worse ODI scores remained...... confounding variables. SUMMARY OF BACKGROUND DATA: The SRS-Schwab Adult Spinal Deformity Classification includes sagittal modifiers considered important for HRQOL and the clinical impact of the classification has been validated in patients from the International Spine Study Group database; however, equivocal...

Enterprise SRS: Leveraging Ongoing Operations To Advance Nuclear Fuel Cycles Research And Development Programs

Energy Technology Data Exchange (ETDEWEB)

Murray, Alice M.; Marra, John E.; Wilmarth, William R.; Mcguire, Patrick W.; Wheeler, Vickie B.

2013-07-03

The Savannah River Site (SRS) is repurposing its vast array of assets to solve future national issues regarding environmental stewardship, national security, and clean energy. The vehicle for this transformation is Enterprise SRS which presents a new, radical view of SRS as a united endeavor for ''all things nuclear'' as opposed to a group of distinct and separate entities with individual missions and organizations. Key among the Enterprise SRS strategic initiatives is the integration of research into facilities in conjunction with on-going missions to provide researchers from other national laboratories, academic institutions, and commercial entities the opportunity to demonstrate their technologies in a relevant environment and scale prior to deployment. To manage that integration of research demonstrations into site facilities, The Department of Energy, Savannah River Operations Office, Savannah River Nuclear Solutions, the Savannah River National Laboratory (SRNL) have established a center for applied nuclear materials processing and engineering research (hereafter referred to as the Center). The key proposition of this initiative is to bridge the gap between promising transformational nuclear fuel cycle processing discoveries and large commercial-scale-technology deployment by leveraging SRS assets as facilities for those critical engineering-scale demonstrations necessary to assure the successful deployment of new technologies. The Center will coordinate the demonstration of R&D technologies and serve as the interface between the engineering-scale demonstration and the R&D programs, essentially providing cradle-to-grave support to the research team during the demonstration. While the initial focus of the Center will be on the effective use of SRS assets for these demonstrations, the Center also will work with research teams to identify opportunities to perform research demonstrations at other facilities. Unique to this approach is the fact

Decommissioning the physics laboratory, building 777-10A, at the Savannah River Site (SRS)

International Nuclear Information System (INIS)

Musall, John C.; Cope, Jeff L.

2008-01-01

SRS recently completed a four year mission to decommission ∼250 excess facilities. As part of that effort, SRS decommissioned a 48,000 ft 2 laboratory that housed four low-power test reactors, formerly used by SRS to determine reactor physics. This paper describes and reviews the decommissioning, with a focus on component segmentation and handling (i.e. hazardous material removal, demolition, and waste handling). The paper is intended to be a resource for engineers, planners, and project managers, who face similar decommissioning challenges. Building 777-10A, located at the south end of SRS's A/M-Area, was built in 1953 and had a gross area of ∼48,000 ft 2 . Building 777-10A had two main areas: a west wing, which housed four experimental reactors and associated equipment; and an east wing, which housed laboratories, and shops, offices. The reactors were located in two separate areas: one area housed the Process Development Pile (PDP) reactor and the Lattice Test Reactor (LTR), while the second area housed the Standard Pile (SP) and the Sub-critical Experiment (SE) reactors. The west wing had five levels: three below and three above grade (floor elevations of -37', -28', -15', 0', +13'/+16' and +27' (roof elevation of +62')), while the east wing had two levels: one below and one above grade (floor elevations of -15' and 0' (roof elevation of +16')). Below-grade exterior walls were constructed of reinforced concrete, ∼1' thick. In general, above-grade exterior walls were steel frames covered by insulation and corrugated, asbestos-cement board. The two interior walls around the PDP/LTR were reinforced concrete ∼5' thick and ∼30' high, while the SP/SE reactors resided in a reinforced, concrete cell with 3.5'-6' thick walls/roof. All other interior walls were constructed of metal studs covered with either asbestos-cement or gypsum board. In general, the floors were constructed of reinforced concrete on cast-in-place concrete beams below-grade and concrete on

The Brazilian version of the SRS-22r questionnaire for idiopathic scoliosis

Directory of Open Access Journals (Sweden)

Paula M. F. Camarini

2013-10-01

Full Text Available BACKGROUND: The SRS-22r questionnaire is a well-accepted instrument used to measure health-related quality of life in patients with idiopathic scoliosis. No validated tool exists in Brazil for idiopathic scoliosis, and the use of the SRS-22r in non-English Laguage contries requires its transcultural adaptation. OBJECTIVE: The objective of this study was to culturally adapt the translated Brazilian version of the SRS-22r questionnaire and to determine its reliability using statistical tests for internal consistency and test-retest reliability. METHOD: The transcultural adaptation process was carried out according to the recommendations of the American Academy of Orthopedic Surgeons. The pre-final version was administered to 44 patients with idiopathic scoliosis. The mean age of the participants was 18.93 years and the mean curve magnitude was 54.6°. A subgroup of 30 volunteers completed the questionnaire a second time one week later to determine the scale's reproducibility. Internal consistency was determined using Cronbach's alpha coefficient, and the test-retest reliability was determined using the Intraclass Correlation Coefficient (ICC. RESULTS: No floor effects were observed using the Brazilian version of the SRS-22r. Ceiling effects were observed in the Pain and Satisfaction with Management domains. The internal consistency values were very good for 3 domains and good for 2 domains. The ICC values were excellent for all domains. CONCLUSIONS: The high values of internal consistency and ICC reproducibility suggest that this version of the questionnaire can be used in Brazilian patients with idiopathic scoliosis.

SU-F-T-574: MLC Based SRS Beam Commissioning - Minimum Target Size Investigation

Energy Technology Data Exchange (ETDEWEB)

Zakikhani, R [Florida Cancer Specialists - Largo, Largo, FL (United States); Able, C [Florida Cancer Specialists - New Port Richey, New Port Richey, FL (United States)

2016-06-15

Purpose: To implement a MLC accelerator based SRS program using small fields down to 1 cm × 1 cm and to determine the smallest target size safe for clinical treatment. Methods: Computerized beam scanning was performed in water using a diode detector and a linac-head attached transmission ion chamber to characterize the small field dosimetric aspects of a 6 MV photon beam (Trilogy-Varian Medical Systems, Inc.). The output factors, PDD and profiles of field sizes 1, 2, 3, 4, and 10 cm{sup 2} were measured and utilized to create a new treatment planning system (TPS) model (AAA ver 11021). Static MLC SRS treatment plans were created and delivered to a homogeneous phantom (Cube 20, CIRS, Inc.) for a 1.0 cm and 1.5 cm “PTV” target. A 12 field DMLC plan was created for a 2.1 cm target. Radiochromic film (EBT3, Ashland Inc.) was used to measure the planar dose in the axial, coronal and sagittal planes. A micro ion chamber (0.007 cc) was used to measure the dose at isocenter for each treatment delivery. Results: The new TPS model was validated by using a tolerance criteria of 2% dose and 2 mm distance to agreement. For fields ≤ 3 cm{sup 2}, the max PDD, Profile and OF difference was 0.9%, 2%/2mm and 1.4% respectively. The measured radiochromic film planar dose distributions had gamma scores of 95.3% or higher using a 3%/2mm criteria. Ion chamber measurements for all 3 test plans effectively met our goal of delivering the dose accurately to within 5% when compared to the expected dose reported by the TPS (1 cm plan Δ= −5.2%, 1.5 cm plan Δ= −2.0%, 2 cm plan Δ= 1.5%). Conclusion: End to end testing confirmed that MLC defined SRS for target sizes ≥ 1.0 cm can be safely planned and delivered.

Reliability and Validity Study of the Finnish Adaptation of Scoliosis Research Society Questionnaire Version SRS-30.

Science.gov (United States)

Kyrölä, Kati; Järvenpää, Salme; Ylinen, Jari; Mecklin, Jukka-Pekka; Repo, Jussi Petteri; Häkkinen, Arja

2017-06-15

A prospective clinical study to test and adapt a Finnish version of the Scoliosis Research Society 30 (SRS-30) questionnaire. The aim of this study was to perform cross-cultural adaptation and evaluate the validity of the adapted Finnish version of the SRS-30 questionnaire. The SRS-30 questionnaire has proved to be a valid instrument in evaluating health-related quality of life (HRQoL) in adolescent and adult population with spine deformities in the United States. Multinational availability requires cross-cultural and linguistic adaptation and validation of the instrument. The SRS-30 was translated into Finnish using accepted methods for translation of quality-of-life questionnaires. A total of 274 adult patients with degenerative radiographic sagittal spinal disorder answered the questionnaire with sociodemographic data, RAND 36-item health survey questionnaire (RAND Corp. Health, Santa Monica, CA, US), Oswestry disability index, DEPS depression scale, and Visual Analog Scale (VAS) back and leg pain scales within 2 weeks' interval. The cohort included patients with and without previous spine surgery. Internal consistency and validity were tested with Cronbach α, intraclass correlation (ICC), standard error of measurement, and Spearman correlation coefficient with 95% confidence intervals (CIs). The internal consistency of SRS-30 was good in both surgery and nonsurgery groups, with Cronbach α 0.853 (95% CI, 0.670 to 0.960) and 0.885 (95% CI, 0.854 to 0.911), respectively. The test-retest reproducibility ICC of the SRS-30 total and subscore domains of patients with stable symptoms was 0.905 (95% CI, 0.870-0.930) and 0.904 (95% CI, 0.871-0.929), respectively. The questionnaire had discriminative validity in the pain, self-image, and satisfaction with management domains compared with other questionnaires. The SRS-30 questionnaire proved to be valid and applicable in evaluating HRQoL in Finnish adult spinal deformity patients. It has two domains related to deformity

7Q10 flows for SRS streams

International Nuclear Information System (INIS)

Chen, K.F.

1996-01-01

The Environmental Transport Group of the Environmental Technology Section was requested to predict the seven-day ten-year low flow (7Q10 flow) for the SRS streams based on historical stream flow records. Most of the historical flow records for the SRS streams include reactor coolant water discharged from the reactors and process water released from the process facilities. The most straight forward way to estimate the stream daily natural flow is to subtract the measured upstream reactor and/or facility daily effluents from the measured downstream daily flow. Unfortunately, this method does not always work, as indicated by the fact that sometimes the measured downstream volumetric flow rates are lower than the reactor effluent volumetric flow rates. For those cases that cannot be analyzed with the simple subtracting method, an alternative method was used to estimate the stream natural flows by statistically separating reactor coolant and process water flow data. The correlation between the calculated 7Q10 flows and the watershed areas for Four Mile Branch and Pen Branch agrees with that calculated by the USGS for Upper Three Runs and Lower Three Runs Creeks. The agreement between these two independent calculations lends confidence to the 7Q10 flow calculations presented in this report

The reliability of nonlinear least-squares algorithm for data analysis of neural response activity during sinusoidal rotational stimulation in semicircular canal neurons.

Science.gov (United States)

Ren, Pengyu; Li, Bowen; Dong, Shiyao; Chen, Lin; Zhang, Yuelin

2018-01-01

Although many mathematical methods were used to analyze the neural activity under sinusoidal stimulation within linear response range in vestibular system, the reliabilities of these methods are still not reported, especially in nonlinear response range. Here we chose nonlinear least-squares algorithm (NLSA) with sinusoidal model to analyze the neural response of semicircular canal neurons (SCNs) during sinusoidal rotational stimulation (SRS) over a nonlinear response range. Our aim was to acquire a reliable mathematical method for data analysis under SRS in vestibular system. Our data indicated that the reliability of this method in an entire SCNs population was quite satisfactory. However, the reliability was strongly negatively depended on the neural discharge regularity. In addition, stimulation parameters were the vital impact factors influencing the reliability. The frequency had a significant negative effect but the amplitude had a conspicuous positive effect on the reliability. Thus, NLSA with sinusoidal model resulted a reliable mathematical tool for data analysis of neural response activity under SRS in vestibular system and more suitable for those under the stimulation with low frequency but high amplitude, suggesting that this method can be used in nonlinear response range. This method broke out of the restriction of neural activity analysis under nonlinear response range and provided a solid foundation for future study in nonlinear response range in vestibular system.

Comparison of SSS and SRS calculated from normal databases provided by QPS and 4D-MSPECT manufacturers and from identical institutional normals

International Nuclear Information System (INIS)

Knollmann, Daniela; Knebel, Ingrid; Gebhard, Michael; Krohn, Thomas; Buell, Ulrich; Schaefer, Wolfgang M.; Koch, Karl-Christian

2008-01-01

There is proven evidence for the importance of myocardial perfusion-single-photon emission computed tomography (SPECT) with computerised determination of summed stress and rest scores (SSS/SRS) for the diagnosis of coronary artery disease (CAD). SSS and SRS can thereby be calculated semi-quantitatively using a 20-segment model by comparing tracer-uptake with values from normal databases (NDB). Four severity-degrees for SSS and SRS are normally used: 99m Tc-tetrofosmin, triple-head-camera, 30 s/view, 20 views/head) from 36 men with a low post-stress test CAD probability and visually normal SPECT findings. Patient group was 60 men showing the entire CAD-spectrum referred for routine perfusion-SPECT. Stress/rest results of automatic quantification of the 60 patients were compared to M-NDB and I-NDB. After reclassifying SSS/SRS into the four severity degrees, kappa (κ) values were calculated to objectify agreement. Mean values (vs M-NDB) were 9.4 ± 10.3 (SSS) and 5.8 ± 9.7 (SRS) for QPS and 8.2 ± 8.7 (SSS) and 6.2 ± 7.8 (SRS) for 4D-MSPECT. Thirty seven of sixty SSS classifications (κ = 0.462) and 40/60 SRS classifications (κ = 0.457) agreed. Compared to I-NDB, mean values were 10.2 ± 11.6 (SSS) and 6.5 ± 10.4 (SRS) for QPS and 9.2 ± 9.3 (SSS) and 7.2 ± 8.6 (SRS) for 4D-MSPECT. Forty four of sixty patients agreed in SSS and SRS (κ = 0.621 resp. 0.58). Considerable differences between SSS/SRS obtained with QPS and 4D-MSPECT were found when using M-NDB. Even using identical patients and identical I-NDB, the algorithms still gave substantial different results. (orig.)

Comparison of SSS and SRS calculated from normal databases provided by QPS and 4D-MSPECT manufacturers and from identical institutional normals.

Science.gov (United States)

Knollmann, Daniela; Knebel, Ingrid; Koch, Karl-Christian; Gebhard, Michael; Krohn, Thomas; Buell, Ulrich; Schaefer, Wolfgang M

2008-02-01

There is proven evidence for the importance of myocardial perfusion-single-photon emission computed tomography (SPECT) with computerised determination of summed stress and rest scores (SSS/SRS) for the diagnosis of coronary artery disease (CAD). SSS and SRS can thereby be calculated semi-quantitatively using a 20-segment model by comparing tracer-uptake with values from normal databases (NDB). Four severity-degrees for SSS and SRS are normally used: or =14. Manufacturers' NDBs (M-NDBs) often do not fit the institutional (I) settings. Therefore, this study compared SSS and SRS obtained with the algorithms Quantitative Perfusion SPECT (QPS) and 4D-MSPECT using M-NDB and I-NDB. I-NDBs were obtained using QPS and 4D-MSPECT from exercise stress data (450 MBq (99m)Tc-tetrofosmin, triple-head-camera, 30 s/view, 20 views/head) from 36 men with a low post-stress test CAD probability and visually normal SPECT findings. Patient group was 60 men showing the entire CAD-spectrum referred for routine perfusion-SPECT. Stress/rest results of automatic quantification of the 60 patients were compared to M-NDB and I-NDB. After reclassifying SSS/SRS into the four severity degrees, kappa values were calculated to objectify agreement. Mean values (vs M-NDB) were 9.4 +/- 10.3 (SSS) and 5.8 +/- 9.7 (SRS) for QPS and 8.2 +/- 8.7 (SSS) and 6.2 +/- 7.8 (SRS) for 4D-MSPECT. Thirty seven of sixty SSS classifications (kappa = 0.462) and 40/60 SRS classifications (kappa = 0.457) agreed. Compared to I-NDB, mean values were 10.2 +/- 11.6 (SSS) and 6.5 +/- 10.4 (SRS) for QPS and 9.2 +/- 9.3 (SSS) and 7.2 +/- 8.6 (SRS) for 4D-MSPECT. Forty four of sixty patients agreed in SSS and SRS (kappa = 0.621 resp. 0.58). Considerable differences between SSS/SRS obtained with QPS and 4D-MSPECT were found when using M-NDB. Even using identical patients and identical I-NDB, the algorithms still gave substantial different results.

Benefits of a Unified LaSRS++ Simulation for NAS-Wide and High-Fidelity Modeling

Science.gov (United States)

Glaab, Patricia; Madden, Michael

2014-01-01

The LaSRS++ high-fidelity vehicle simulation was extended in 2012 to support a NAS-wide simulation mode. Since the initial proof-of-concept, the LaSRS++ NAS-wide simulation is maturing into a research-ready tool. A primary benefit of this new capability is the consolidation of the two modeling paradigms under a single framework to save cost, facilitate iterative concept testing between the two tools, and to promote communication and model sharing between user communities at Langley. Specific benefits of each type of modeling are discussed along with the expected benefits of the unified framework. Current capability details of the LaSRS++ NAS-wide simulations are provided, including the visualization tool, live data interface, trajectory generators, terminal routing for arrivals and departures, maneuvering, re-routing, navigation, winds, and turbulence. The plan for future development is also described.

75 FR 32158 - Information Collection; SRS Publications Evaluation Card

Science.gov (United States)

2010-06-07

... facilitate entry into the building. Additionally, the public may inspect comments received on the World Wide Web, at http://www.srs.fs.usda.gov/pubeval . FOR FURTHER INFORMATION CONTACT: Louise Wilde, Science... should be addressed to Forest Service, USDA, Southern Research Station, Science Delivery Group, 200 W.T...

SRS environmental air surveillance program 1954-2015: General trends

Energy Technology Data Exchange (ETDEWEB)

Abbott, K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Jannik, T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2016-06-02

The radiological monitoring program at SRS was established under the DuPont Company in June 1951 and was used as a measurement of the effectiveness of plant controls and as an authoritative record of environmental conditions surrounding the plant. It also served as a method of demonstrating compliance with applicable federal regulations and guidance. This document serves as a general summary of changes made specifically to the environmental air monitoring program since its inception, and a discussion of the general trends seen in the air monitoring program at SRS from 1954 to 2015. Initially, the environmental air surveillance program focused not only on releases from SRS but also on fallout from various weapons testing performed through the end of 1978. Flypaper was used to measure the amount of fallout in the atmosphere during this period, and was present at each of the 10 monitoring stations. By 1959, all site stacks were included in the air monitoring program to determine their contribution to the airborne radioactivity onsite, and the number of air surveillance samplers rose to 18. This trend of an increased number of sampling locations continued to a peak of 35 sampling locations before shifting to a downward trend in the mid-1990s. In 1962, 4 outer-range samplers were placed in Savannah and Macon, GA, and in Greenville and Columbia, SC. Until 1976, air samplers were simply placed around the perimeter of the various operation locations (after 1959, this included stacks to determine their contribution to the airborne radioactivity), with the intent of creating as representative a distribution as possible of the air surrounding operations.

SRS Public Involvement in Waste Management Has Resulted in Effective Decisions Supported by the Public Including Disposal Changes and Top-to-Bottom Review Initiative Consensus

International Nuclear Information System (INIS)

Goldston, W. T.; Villasor, H. P.

2003-01-01

In the Savannah River Site's (SRS') Solid Waste Management Program, a key to success is the Public Involvement Program. The Solid Waste Division at SRS manages the site's transuranic, low-level, mixed, and hazardous wastes. All decisions associated with management of this waste are of interest to the public and successful program implementation would be impossible without a vigorous public involvement program. The SRS Solid Waste Division (SWD) and its Department of Energy (DOE) customer developed, implemented, and maintain a comprehensive public participation and communications program. It is staffed by public participation and technical specialists to ensure information is presented in a manner that is technically accurate while being tailored for understanding by people without a technical background. The program provides the public with accurate, complete, timely information and early meaningful participation opportunities. It also fulfills the public participation activities required by laws, regulations, DOE Orders, and negotiated agreements. The primary goal of the SWD Public Participation Program is to fulfill the objectives of the SWD and SRS Strategic Plans to ''build trust and communicate openly, honestly, and responsibly with employees, customers, stakeholders, and regulators,'' and to ''work to extend the support of external stakeholders for the pursuit of SRS and DOE Complex business goals.'' This paper focuses on the public participation program goals, the implementation through formal plans and objectives, targeted waste management programs and specific audiences, and specific effects of the program on waste management activities. A discussion of the DOE and contractor teaming along with how plans are carried out is also included

Development of a solvent extraction process for cesium removal from SRS tank waste

International Nuclear Information System (INIS)

Leonard, R.A.; Conner, C.; Liberatore, M.W.; Sedlet, J.; Aase, S.B.; Vandegrift, G.F.; Delmau, L.H.; Bonnesen, P.V.; Moyer, B.A.

2001-01-01

An alkaline-side solvent extraction process was developed for cesium removal from Savannah River Site (SRS) tank waste. The process was invented at Oak Ridge National Laboratory and developed and tested at Argonne National Laboratory using singlestage and multistage tests in a laboratory-scale centrifugal contactor. The dispersion number, hydraulic performance, stage efficiency, and general operability of the process flowsheet were determined. Based on these tests, further solvent development work was done. The final solvent formulation appears to be an excellent candidate for removing cesium from SRS tank waste.

Effect of polariton propagation on spectra of SRS amplification and CARS from polaritons

International Nuclear Information System (INIS)

Orlov, Sergei N; Polivanov, Yurii N

2001-01-01

The properties of k spectra of SRS amplification and CARS from polaritons caused by 'running out' of polaritons from the volume of their interaction with incident light beams are theoretically analysed. It is shown that the shape and width of the spectra depend on the relation between the size of the overlap region of exciting waves in a crystal along the direction of polariton propagation and the mean free path of polaritons. The conditions are found under which the widths of SRS amplification and CARS spectra give information on the polariton decay. (nonlinear optical phenomena and devices)

High temperature vitrification of surrogate Savannah River Site (SRS) mixed waste materials

International Nuclear Information System (INIS)

Applewhite-Ramsey, A.; Schumacher, R.F.; Spatz, T.L.; Newsom, R.A.; Circeo, L.J.; Danjaji, M.B.

1995-01-01

The Savannah River Technology Center (SRTC) has been funded through the DOE Office of Technology Development (DOE-OTD) to investigate high-temperature vitrification technologies for the treatment of diverse low-level and mixed wastes. High temperature vitrification is a likely candidate for processing heterogeneous solid wastes containing low levels of activity. Many SRS wastes fit into this category. Plasma torch technology is one high temperature vitrification method. A trial demonstration of plasma torch processing is being performed at the Georgia Institute of Technology on surrogate SRS wastes. This effort is in cooperation with the Engineering Research and Development Association of Georgia Universities (ERDA) program. The results of phase 1 of these plasma torch trials will be presented

Hydrostratigraphy of the General Separations Area, Savannah River Site (SRS), South Carolina

International Nuclear Information System (INIS)

Aadland, R.K.; Harris, M.K.; Lewis, C.M.; Gaughan, T.F.; Westbrook, T.M.

1991-01-01

Detailed analysis and synthesis of geophysical, core, and hydrologic data from 230 wells were used to delineate the hydrostratigraphy and aquifer characteristics of the General Separations Area at SRS. The study area is hydrologically bounded on the north and northwest by Upper Three Runs Creek (UTRC) and on the south by Fourmile Branch (FB). The Cretaceous-Tertiary sedimentary sequence underlying the study area is divided into two Aquifer Systems; in ascending order, Aquifer Systems I and 11. The study concentrated on Aquifer System U, which includes all the Tertiary sediments above the Black Mingo Group (Paleocene) to the water table. This report includes a series of lithostratigraphic cross-sections, piezometric gradient profiles, head ratio contour maps, aquifer isopach maps, and potentiometric surface maps which illustrate the aquifer characteristics of the study area

Hydrostratigraphy of the General Separations Area, Savannah River Site (SRS), South Carolina

Energy Technology Data Exchange (ETDEWEB)

Aadland, R.K.; Harris, M.K.; Lewis, C.M.; Gaughan, T.F. (Westinghouse Savannah River Co., Aiken, SC (United States)); Westbrook, T.M. (Dames and Moore, Atlanta, GA (United States))

1991-01-01

Detailed analysis and synthesis of geophysical, core, and hydrologic data from 230 wells were used to delineate the hydrostratigraphy and aquifer characteristics of the General Separations Area at SRS. The study area is hydrologically bounded on the north and northwest by Upper Three Runs Creek (UTRC) and on the south by Fourmile Branch (FB). The Cretaceous-Tertiary sedimentary sequence underlying the study area is divided into two Aquifer Systems; in ascending order, Aquifer Systems I and 11. The study concentrated on Aquifer System U, which includes all the Tertiary sediments above the Black Mingo Group (Paleocene) to the water table. This report includes a series of lithostratigraphic cross-sections, piezometric gradient profiles, head ratio contour maps, aquifer isopach maps, and potentiometric surface maps which illustrate the aquifer characteristics of the study area.

ANALYSIS OF SPECIAL WASTE CONFIGURATIONS AT THE SRS WASTE MANAGEMENT FACILITIES

International Nuclear Information System (INIS)

Casella, V; Raymond Dewberry, R

2007-01-01

Job Control Waste (JCW) at the Savannah River Site (SRS) Solid Waste Management Facilities (SWMF) may be disposed of in special containers, and the analysis of these containers requires developing specific analysis methodologies. A method has been developed for the routine assay of prohibited items (liquids, etc.) contained in a 30-gallon drum that is then placed into a 55-gallon drum. Method development consisted of system calibration with a NIST standard at various drum-to-detector distances, method verification with a liquid sample containing a known amount of Pu-238, and modeling the inner container using Ortec Isotopic software. Using this method for measurement of the known standard in the drum-in-drum configuration produced excellent agreement (within 15%) with the known value. Savannah River Site Solid Waste Management also requested analysis of waste contained in large black boxes (commonly 18-feet x 12-feet x 7-feet) stored at the SWMF. These boxes are frequently stored in high background areas and background radiation must be considered for each analysis. A detection limit of less than 150 fissile-gram-equivalents (FGE) of TRU waste is required for the black-box analyses. There is usually excellent agreement for the measurements at different distances and measurement uncertainties of about 50% are obtained at distances of at least twenty feet from the box. This paper discusses the experimental setup, analysis and data evaluation for drum-in-drum and black box waste configurations at SRS

Calculated Performance Of The Variable-Polarization Undulator Upgrade To The Daresbury SRS Soft X-Ray Undulator Beamline

International Nuclear Information System (INIS)

Roper, Mark D.; Bird, Daniel T.

2004-01-01

The soft x-ray beamline 5U1 on the Daresbury Laboratory SRS currently uses a planar undulator, producing linearly polarized radiation in the range 100 to 1000 eV. The undulator is soon to be replaced by a variable-polarization device of the Apple II design. The aim is to produce circularly polarized light in the energy range 265 to 1000 eV, covering the K-edges of C, N and O, and the first row transition element L-edges. This will greatly enhance the provision of circularly polarized soft-x-rays on the SRS and open up new opportunities for experimenters. The device will also produce linear polarization with a selectable angle of polarization with respect to the orbit plane, which is currently unavailable on the SRS. In order to provide the coverage over this energy range, we are exploiting the relatively large emittance of the SRS to allow us to use the second and third harmonics even in circular polarization mode. This paper presents the expected beamline output in various polarization modes and the predicted degree of polarization

Evaluation of no-MST operations in the SRS ARP for Hanford LAWPS

Energy Technology Data Exchange (ETDEWEB)

Herman, D. [Savannah River Site (SRS), Aiken, SC (United States)

2016-11-14

The Savannah River Site (SRS) Actinide Removal Process has been processing salt waste since 2008. This process includes a filtration step in the 512-S facility. Initial operations included the addition, or strike, of monosodium titanate (MST) to remove soluble actinides and strontium. The added MST and any entrained sludge solids were then separated from the supernate by cross flow filtration. During this time, the filter operations have, on many occasions, been the bottleneck process limiting the rate of salt processing. Recently, 512-S- has started operations utilizing “No-MST” where the MST actinide removal strike was not performed and the supernate was simply pre-filtered prior to Cs removal processing. Direct filtration of decanted tank supernate, as demonstrated in 512-S, is the proposed method of operation for the Hanford Low Activity Waste Pretreatment System (LAWPS) facility. Processing decanted supernate without MST solids has been demonstrated for cross flow filtration to provide a significant improvement in production with the SRS Salt Batches 8 and 9 feed chemistries. The average filtration rate for the first 512-S batch processing cycle using No-MST has increased filtrate production by over 35% of the historical average. The increase was sustained for more than double the amount of filtrate batches processed before cleaning of the filter was necessary. While there are differences in the design of the 512-S and Hanford filter systems, the 512-S system should provide a reasonable indication of LAWPS filter performance with similar feed properties. Based on the data from the 512-S facility and with favorable feed properties, the LAWPS filter, as currently sized at over twice the size of the 512-S filter (532 square feet filtration area versus 235 square feet), has the potential to provide sustained filtrate production at the upper range of the planned LAWPS production rate of 17 gpm.

Computationally based methodology for reengineering the high-level waste planning process at SRS

International Nuclear Information System (INIS)

Paul, P.K.; Gregory, M.V.; Wells, M.N.

1997-01-01

The Savannah River Site (SRS) has started processing its legacy of 34 million gallons of high-level radioactive waste into its final disposable form. The SRS high-level waste (HLW) complex consists of 51 waste storage tanks, 3 evaporators, 6 waste treatment operations, and 2 waste disposal facilities. It is estimated that processing wastes to clean up all tanks will take 30+ yr of operation. Integrating all the highly interactive facility operations through the entire life cycle in an optimal fashion-while meeting all the budgetary, regulatory, and operational constraints and priorities-is a complex and challenging planning task. The waste complex operating plan for the entire time span is periodically published as an SRS report. A computationally based integrated methodology has been developed that has streamlined the planning process while showing how to run the operations at economically and operationally optimal conditions. The integrated computational model replaced a host of disconnected spreadsheet calculations and the analysts' trial-and-error solutions using various scenario choices. This paper presents the important features of the integrated computational methodology and highlights the parameters that are core components of the planning process

SRS-A leukotrienes decrease the activity of human respiratory cilia

DEFF Research Database (Denmark)

Bisgaard, H; Pedersen, M

1987-01-01

We have studied the effects of the slow reacting substance of anaphylaxis (SRS-A) constituents leukotrienes (LT) C4 and D4 on the ciliary activity of human respiratory cells. The ciliary beat frequency on human nasal cells harvested by cell scraping from the inferior turbinate was measured...

Input to the PRAST computer code used in the SRS probabilistic risk assessment

International Nuclear Information System (INIS)

Kearnaghan, D.P.

1992-01-01

The PRAST (Production Reactor Algorithm for Source Terms) computer code was developed by Westinghouse Savannah River Company and Science Application International Corporation for the quantification of source terms for the SRS Savannah River Site (SRS) Reactor Probabilistic Risk Assessment. PRAST requires as input a set of release fractions, decontamination factors, transfer fractions and source term characteristics that accurately reflect the conditions that are evaluated by PRAST. This document links the analyses which form the basis for the PRAST input parameters. In addition, it gives the distribution of the input parameters that are uncertain and considered to be important to the evaluation of the source terms to the environment

Report on SRS activities to March, 1981

International Nuclear Information System (INIS)

Munro, I.H.

1981-10-01

In this first Annual Report on synchrotron radiation research and related activities since the completion of the storage ring (the SRS) at Daresbury Laboratory a summary is given of progress on the storage ring itself, on beamlines, experimental stations, data acquisition and processing facilities and on the build-up of ancillary laboratories and equipment. In appendices a bibliography of synchrotron radiation research publications from March 1977 to March 1981 and a cumulative list of research grants and agreements approved by the SRFC from March 1977 to March 1981 are given. (U.K.)

Ichthyoplankton entrainment study at the SRS Savannah River water intakes for Westinghouse Savannah River Company

International Nuclear Information System (INIS)

Paller, M.

1992-01-01

Cooling water for L and K Reactors and makeup water for Par Pond is pumped from the Savannah River at the 1G, 3G, and 5G pump houses. Ichthyoplankton (drifting fish larvae and eggs) from the river are entrained into the reactor cooling systems with the river water and passed through the reactor's heat exchangers where temperatures may reach 70 degrees C during full power operation. Ichthyoplankton mortality under such conditions is assumed to be 100 percent. The number of ichthyoplankton entrained into the cooling system depends on a variety of variables, including time of year, density and distribution of ichthyoplankton in the river, discharge levels in the river, and the volume of water withdrawn by the pumps. Entrainment at the 1 G pump house, which is immediately downstream from the confluence of Upper Three Runs Creek and the Savannah River, is also influenced by discharge rates and ichthyoplankton densities in Upper Three Runs Creek. Because of the anticipated restart of several SRS reactors and the growing concern surrounding striped bass and American shad stocks in the Savannah River, the Department of Energy requested that the Environmental Sciences Section (ESS) of the Savannah River Laboratory sample ichthyoplankton at the SRS Savannah River intakes. Dams ampersand Moore, Inc., under a contract with Westinghouse Savannah River Company performed the sampling and data analysis for the ESS

Pro-recombination role of Srs2 protein requires SUMO (small ubiquitin-like modifier) but is independent of PCNA (proliferating cell nuclear antigen) interaction

DEFF Research Database (Denmark)

Kolesar, Peter; Altmannova, Veronika; Pinela da Silva, Sonia Cristina

2016-01-01

of SIM in asrs2ΔPIMstrain leads to a decrease in recombination, indicating a pro-recombination role of SUMO. Thus SIM has an ambivalent function in Srs2 regulation; it not only mediates interaction with SUMO-PCNA to promote the anti-recombination function but it also plays a PCNA-independent pro......-recombination role, probably by stimulating the formation of recombination complexes. The fact that deletion of PIM suppresses the phenotypes of Srs2 lacking SIM suggests that proper balance between the anti-recombination PCNA-bound and pro-recombination pools of Srs2 is crucial. Notably, sumoylation of Srs2 itself...

EPR of VHal centres in SrS

International Nuclear Information System (INIS)

Seeman, V.; Danilkin, M.; Must, M.; Ots, A.; Paernoja, E.; Pung, L.; Tarkpea, K.

2006-01-01

V Hal centres were studied by EPR in SrS doped with halogens after X-raying the samples at 77 K. V Hal centre arises when a hole is captured by sulphide-ion next to a cation vacancy with a halogen ion substituting the opposite sulphide-ion. EPR parameters and thermal decay characteristics are measured for V Cl , V Br , and V I centres. The efficiency of different halogens to produce and stabilise cation vacancies is shown to vary for different alkaline earth sulphides. (copyright 2006 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

Degradation and mineralisation of diuron by Sphingomonas sp. SRS2 and its potential for remediating at a realistic µg L(-1) diuron concentration.

Science.gov (United States)

Sørensen, Sebastian R; Juhler, René K; Aamand, Jens

2013-11-01

Low concentrations (10(-6)-10(-9) g L(-1)) of the herbicide diuron are occasionally detected as water contaminants in areas around the world where the herbicide is used extensively. Remediation of contaminated waters using diuron-mineralising bacteria is a possible approach for cleaning these resources. However, few diuron-mineralising strains have been isolated. Here, the ability of Sphingomonas sp. SRS2, a well-known soil bacterium capable of degrading the structurally related herbicide isoproturon, to mineralise diuron at realistically low concentrations is tested. Strain SRS2 readily degraded the dimethylurea side chain, while no or only slow mineralisation of the ring structure was determined. By monitoring metabolites, it was determined that SRS2 initially degraded diuron by two successive N-demethylations followed by cleavage of the urea group to 3,4-dichloroaniline (3,4-DCA). Mineralisation of low diuron concentrations by SRS2 was detected and could be stimulated by the addition of a complex nutrient source. Further enhancement of the mineralisation activity was obtained by combining SRS2 with the 3,4-DCA-mineralising Variovorax sp. SRS16. This work demonstrates that Sphingomonas sp. SRS2 is a promising candidate for bioaugmentation, alone or in combination with other strains, and that enhanced diuron mineralisation at realistically low concentrations can be achieved. © 2013 Society of Chemical Industry.

Computation of USGS Soil UHS and Comparison to NEHRP and PC 1 Seismic Response; FINAL

International Nuclear Information System (INIS)

Lee, R.C.

2000-01-01

Recently, new site-specific seismic design response spectra were developed for Savannah River Site (SRS) performance category (PC) 1,2,3 and 4 structures, systems and components (SSCs) (WSRC, 1997, 1998) in accordance with DOE Standards. The lower performance categories (PC1 and PC2) site-specific design basis were not compatible with the response spectrum generated if building code guidelines were used (National Earthquake Hazard Reduction Program Recommended Provisions for Seismic Regulations for New Building, (NEHRP), 1997). These differences in criteria and approach should be documented and understood. Thus, Westinghouse Savannah River Company (WSRC) initiated this study to evaluate the difference between the building code hazard assessment (NEHRP) and the site-specific hazard evaluations used for SRS design

Production of refolded Toxoplasma gondii recombinant SAG1-related sequence 3 (SRS3) and its use for serodiagnosis of human toxoplasmosis.

Science.gov (United States)

Mirzadeh, Abolfazl; Saadatnia, Geita; Golkar, Majid; Babaie, Jalal; Noordin, Rahmah

2017-05-01

SAG1-related sequence 3 (SRS3) is one of the major Toxoplasma gondii tachyzoite surface antigens and has been shown to be potentially useful for the detection of toxoplasmosis. This protein is highly conformational due to the presence of six disulfide bonds. To achieve solubility and antigenicity, SRS3 depends on proper disulfide bond formation. The aim of this study was to over-express the SRS3 protein with correct folding for use in serodiagnosis of the disease. To achieve this, a truncated SRS3 fusion protein (rtSRS3) was produced, containing six histidyl residues at both terminals and purified by immobilized metal affinity chromatography. The refolding process was performed through three methods, namely dialysis in the presence of chemical additives along with reduced/oxidized glutathione and drop-wise dilution methods with reduced/oxidized glutathione or reduced DTT/oxidized glutathione. Ellman's assay and ELISA showed that the protein folding obtained by the dialysis method was the most favorable, probably due to the correct folding. Subsequently, serum samples from individuals with chronic infection (n = 76), probable acute infection (n = 14), and healthy controls (n = 81) were used to determine the usefulness of the refolded rtSRS3 for Toxoplasma serodiagnosis. The results of the developed IgG-ELISA showed a diagnostic specificity of 91% and a sensitivity of 82.89% and 100% for chronic and acute serum samples, respectively. In conclusion, correctly folded rtSRS3 has the potential to be used as a soluble antigen for the detection of human toxoplasmosis. Copyright © 2017 Elsevier Inc. All rights reserved.

SU-F-T-584: Investigating Correction Methods for Ion Recombination Effects in OCTAVIUS 1000 SRS Measurements

International Nuclear Information System (INIS)

Knill, C; Snyder, M; Rakowski, J; J, Burmeister; Zhuang, L; Matuszak, M

2016-01-01

Purpose: PTW’s Octavius 1000 SRS array performs IMRT QA measurements with liquid filled ionization chambers (LICs). Collection efficiencies of LICs have been shown to change during IMRT delivery as a function of LINAC pulse frequency and pulse dose, which affects QA results. In this study, two methods were developed to correct changes in collection efficiencies during IMRT QA measurements, and the effects of these corrections on QA pass rates were compared. Methods: For the first correction, Matlab software was developed that calculates pulse frequency and pulse dose for each detector, using measurement and DICOM RT Plan files. Pulse information is converted to collection efficiency and measurements are corrected by multiplying detector dose by ratios of calibration to measured collection efficiencies. For the second correction, MU/min in daily 1000 SRS calibration was chosen to match average MU/min of the VMAT plan. Usefulness of derived corrections were evaluated using 6MV and 10FFF SBRT RapidArc plans delivered to the OCTAVIUS 4D system using a TrueBeam equipped with an HD- MLC. Effects of the two corrections on QA results were examined by performing 3D gamma analysis comparing predicted to measured dose, with and without corrections. Results: After complex Matlab corrections, average 3D gamma pass rates improved by [0.07%,0.40%,1.17%] for 6MV and [0.29%,1.40%,4.57%] for 10FFF using [3%/3mm,2%/2mm,1%/1mm] criteria. Maximum changes in gamma pass rates were [0.43%,1.63%,3.05%] for 6MV and [1.00%,4.80%,11.2%] for 10FFF using [3%/3mm,2%/2mm,1%/1mm] criteria. On average, pass rates of simple daily calibration corrections were within 1% of complex Matlab corrections. Conclusion: Ion recombination effects can potentially be clinically significant for OCTAVIUS 1000 SRS measurements, especially for higher pulse dose unflattened beams when using tighter gamma tolerances. Matching daily 1000 SRS calibration MU/min to average planned MU/min is a simple correction that

Recent advances in SRS on hydrogen isotope separation using thermal cycling absorption process

Energy Technology Data Exchange (ETDEWEB)

Xiao, X.; Kit Heung, L.; Sessions, H.T. [Savannah River National Laboratory - SRNL, Aiken, SC (United States)

2015-03-15

TCAP (Thermal Cycling Absorption Process) is a gas chromatograph in principle using palladium in the column packing, but it is unique in the fact that the carrier gas, hydrogen, is being isotopically separated and the system is operated in a semi-continuous manner. TCAP units are used to purify tritium. The recent TCAP advances at Savannah River Site (SRS) include compressor-free concept for heating/cooling, push and pull separation using an active inverse column, and compact column design. The new developments allow significantly higher throughput and better reliability from 1/10 of the current production system's footprint while consuming 60% less energy. Various versions are derived in the meantime for external customers to be used in fusion energy projects.

Use of Remote Technology in the Surface Water Environmental Monitoring Program at SRS Reducing Measurements in the Field - 13336

International Nuclear Information System (INIS)

Eddy, T.; Terry, B.; Meyer, A.; Hall, J.; Allen, P.; Hughey, D.; Hartley, T.

2013-01-01

There are a wide range of sensor and remote technology applications available for use in environmental monitoring programs. Each application has its own set of limitations and can be challenging when attempting to utilize it under diverse environmental field conditions. The Savannah River Site Environmental Monitoring Program has implemented several remote sensing and surface water flow technologies that have increased the quality of the data while reducing the number of field measurements. Implementation of this technology reduced the field time for personnel that commute across the Savannah River Site (SRS) over a span of 310 square miles. The wireless surface water flow technology allows for immediate notification of changing field conditions or equipment failure thus reducing data-loss or erroneous field data and improving data-quality. This wireless flow technology uses the stage-to-flow methodology coupled with implementation of a robust highly accurate Acoustic Doppler Profiler system for measuring discharge under various field conditions. Savings for implementation of the wireless flow application and Flowlink R technology equates to approximately 1175 hours annually for the radiological liquid effluent and surveillance programs. The SonTek River Suveyor and Flowtracker technologies are utilized for calibration of the wireless flow monitoring devices in the site streams and validation of effluent flows at the SRS. Implementation of similar wireless devices is also planned in the National Pollutant Discharge Elimination System (NPDES) Storm-water Monitoring Program. SRS personnel have been developing a unique flow actuator device. This device activates an ISCO TM automated sampler under flowing conditions at storm-water outfall locations across the site. This technology is unique in that it was designed to be used under field conditions with rapid changes in flow and sedimentation where traditional actuators have been unsuccessful in tripping the automated

The efficiency of parameter estimation of latent path analysis using summated rating scale (SRS) and method of successive interval (MSI) for transformation of score to scale

Science.gov (United States)

Solimun, Fernandes, Adji Achmad Rinaldo; Arisoesilaningsih, Endang

2017-12-01

Research in various fields generally investigates systems and involves latent variables. One method to analyze the model representing the system is path analysis. The data of latent variables measured using questionnaires by applying attitude scale model yields data in the form of score, before analyzed should be transformation so that it becomes data of scale. Path coefficient, is parameter estimator, calculated from scale data using method of successive interval (MSI) and summated rating scale (SRS). In this research will be identifying which data transformation method is better. Path coefficients have smaller varieties are said to be more efficient. The transformation method that produces scaled data and used in path analysis capable of producing path coefficients (parameter estimators) with smaller varieties is said to be better. The result of analysis using real data shows that on the influence of Attitude variable to Intention Entrepreneurship, has relative efficiency (ER) = 1, where it shows that the result of analysis using data transformation of MSI and SRS as efficient. On the other hand, for simulation data, at high correlation between items (0.7-0.9), MSI method is more efficient 1.3 times better than SRS method.

Two items: Transcription of a presentation by Dr. E. L. Albenesius, ''SRS burial ground operation from an historical perspective''; video tape entitled ''Burial ground operation''

International Nuclear Information System (INIS)

Holcomb, H.P.

1992-01-01

On February 6, 1992, approximately 35 SRS personnel from DOE, WSRC, and Dames and Moore attended a very informative talk given by Dr. E.L. Albenesius who discussed the operation of the SRS Burial Ground from an historical perspective. Dr. Albenesius, a Du Point retiree, formerly served as research manager of SRL's Environmental Effects and Solid Waste Management Technology Divisions among other assignments. One notable point Dr. Albenesius made was in answer to a question concerning what was the most important thing that could be done to reduce the hazard to man from buried waste. His response was to remove as much plutonium as practical prior to closure. In order to preserve this valuable information for the record, the program was audiotaped from which a point-by-point chronological transcription, with minor editing, was prepared

TESTING OF ENHANCED CHEMICAL CLEANING OF SRS ACTUAL WASTE TANK 5F AND TANK 12H SLUDGES

Energy Technology Data Exchange (ETDEWEB)

Martino, C.; King, W.

2011-08-22

Forty three of the High Level Waste (HLW) tanks at the Savannah River Site (SRS) have internal structures that hinder removal of the last approximately five thousand gallons of waste sludge solely by mechanical means. Chemical cleaning can be utilized to dissolve the sludge heel with oxalic acid (OA) and pump the material to a separate waste tank in preparation for final disposition. This dissolved sludge material is pH adjusted downstream of the dissolution process, precipitating the sludge components along with sodium oxalate solids. The large quantities of sodium oxalate and other metal oxalates formed impact downstream processes by requiring additional washing during sludge batch preparation and increase the amount of material that must be processed in the tank farm evaporator systems and the Saltstone Processing Facility. Enhanced Chemical Cleaning (ECC) was identified as a potential method for greatly reducing the impact of oxalate additions to the SRS Tank Farms without adding additional components to the waste that would extend processing or increase waste form volumes. In support of Savannah River Site (SRS) tank closure efforts, the Savannah River National Laboratory (SRNL) conducted Real Waste Testing (RWT) to evaluate an alternative to the baseline 8 wt. % OA chemical cleaning technology for tank sludge heel removal. The baseline OA technology results in the addition of significant volumes of oxalate salts to the SRS tank farm and there is insufficient space to accommodate the neutralized streams resulting from the treatment of the multiple remaining waste tanks requiring closure. ECC is a promising alternative to bulk OA cleaning, which utilizes a more dilute OA (nominally 2 wt. % at a pH of around 2) and an oxalate destruction technology. The technology is being adapted by AREVA from their decontamination technology for Nuclear Power Plant secondary side scale removal. This report contains results from the SRNL small scale testing of the ECC process

Hybrid Microwave Treatment of SRS TRU and Mixed Wastes

International Nuclear Information System (INIS)

Wicks, G.G.

1999-01-01

A new process, using hybrid microwave energy, has been developed as part of the Strategic Research and Development program and successfully applied to treatment of a wide variety of non-radioactive materials, representative of SRS transuranic (TRU) and mixed wastes. Over 35 simulated (non-radioactive) TRU and mixed waste materials were processed individually, as well as in mixed batches, using hybrid microwave energy, a new technology now being patented by Westinghouse Savannah River Company (WSRC)

SRS Behaviour with a superconducting 5-Tesla wiggler insertion

International Nuclear Information System (INIS)

Suller, V.P.; Marks, N.; Poole, M.W.; Walker, R.P.

1983-01-01

A 5 Tesla superconducting wavelength shifting wiggler magnet has been inserted into the SRS lattice. Observations have been made of the behaviour of the stored electron beam with the magnet powered. Betatron tune shifts and modulation of the betatron function have been measured and good agreement obtained with theory. Closed orbit changes have been examined and the stored beam lifetime optimised. The magnet is fully operational and is producing intense x-ray beams for users

Thermal analyses of SRS Pu storage cans inside BNFL 3013 container

International Nuclear Information System (INIS)

Paul, P.K.

1999-10-01

Plutonium metal is stored at the Savannah River Site (SRS) using different storage can configurations. The temperatures at different locations in the storage configuration play an important role in designing and configuring different storage arrangements. The present work consists of calculating temperatures at different locations in two different storage configurations

Involverende undervisning med web- og SMS-baseret Student Response Systems

DEFF Research Database (Denmark)

Kjær, Christopher; Larsen, Søren

underviseren kan stille spørgsmål til de studerende i undervisningslokalet og med det samme se, hvad de studerende har svaret. Den studerende svarer via sin mobiltelefon, tablet eller bærbare PC. Aktiviteter 1. Introduktion til SRS – pædagogikken og mulighederne 2. Cases på konkret brug af SRS fra SDU og KU 3...

Reliability and validity of the adapted Greek version of scoliosis research society – 22 (SRS-22 questionnaire

Directory of Open Access Journals (Sweden)

Christodoulou Evangelos A

2009-07-01

Full Text Available Abstract Background The SRS-22 is a valid instrument for the assessment of the health related quality of life of patients with Idiopathic scoliosis. The SRS-22 questionnaire was developed in USA and has been widely used in the English speaking countries. Recently it has been translated and validated in many other languages. The purpose of this study is to evaluate the reliability and validity of the adapted Greek version of the refined Scoliosis Research Society-22 Questionnaire. Methods Following the steps of cross – cultural adaptation the adapted Greek version of the SRS-22 questionnaire and a validated Greek version of the SF-36 questionnaire were mailed to 68 patients treated surgically for Idiopathic Scoliosis. 51 out of the 68 patients returned the 1st set of questionnaires, while a second set was emailed to 30 randomly selected patients of the first time responders. 20 out of the 30 patients returned the 2nd set. The mean age at the time of operation was16,2 years and the mean age at the time of evaluation was 21,2 years. Descriptive statistics for content analysis were calculated. Reliability assessment was determined by estimating Cronbach's α and intraclass correlation coefficient (ICC respectively. Concurrent validity was evaluated by comparing SRS-22 domains with relevant domains in the SF-36 questionnaire using Pearson's Correlation Coefficient (r. Results The calculated Cronbach's α of internal consistency for three of the corresponding domains (pain 0.85; mental health 0.87; self image 0.83 were very satisfactory and for two domains (function/activity 0.72 and satisfaction 0.67 were good. The ICC of all domains of SRS-22 questionnaire was high (ICC>0.70, demonstrating very satisfactory or excellent test/retest reproducibility. Considering concurrent validity all correlations were found to be statistically significant at the 0.01 level among related domains and generally demonstrated high correlation coefficient. Conclusion

Evaluation of Retro recon for SRS planning correction according to the error of recognize to coordinate

Energy Technology Data Exchange (ETDEWEB)

Moon, Hyeon Seok; Jeong, Deok Yang; Do, Gyeong Min; Lee, Yeong Cheol; KIm, Sun Myung; Kim, Young Bun [Dept. of Radiation Oncology, Korea University Guro Hospital, Seoul (Korea, Republic of)

2016-12-15

The purpose of this study was to evaluate the Retro recon in SRS planning using BranLAB when stereotactic location error occurs by metal artifact. By CT simulator, image were acquired from head phantom(CIRS, PTW, USA). To observe stereotactic location recognizing and beam hardening, CT image were approved by SRS planning system(BrainLAB, Feldkirchen, Germany). In addition, we compared acquisition image(1.25mm slice thickness) and Retro recon image(using for 2.5 mm, 5mm slice thickness). To evaluate these three images quality, the test were performed by AAPM phantom study. In patient, it was verified stereotactic location error. All the location recognizing error did not occur in scanned image of phantom. AAPM phantom scan images all showed the same trend. Contrast resolution and Spatial resolution are under 6.4 mm, 1.0 mm. In case of noise and uniformity, under 11, 5 of HU were measured. In patient, the stereotactic location error was not occurred at reconstructive image. For BrainLAB planning, using Retro recon were corrected stereotactic error at beam hardening. Retro recon may be the preferred modality for radiation treatment planning and approving image quality.

An evaluation of the ecological consequences of partial-power operation of the K Reactor, SRS

International Nuclear Information System (INIS)

Gladden, J.B.; Mackey, H.E.; Paller, M.H.; Specht, W.L.; Wike, L.D.; Wilde, E.W.

1991-06-01

The K Reactor at the Savannah River Site (SRS) shut-down in spring 1988 for maintenance and safety upgrades. Since that time the receiving stream for thermal effluent, Indian Grave Branch and Pen Branch, have undergone a pattern of post-thermal recovery that is typical of other SRS streams following removal of thermal stress. Divesity of fish and aquatic macroinvertebrate communities has increased and available habitats have been colonized by numerous species of herbaceous and woody plants. K Reactor is scheduled to resume operation in 1991 and operate through 1992 without a cooling tower to cool the discharge. It is likely that the reactor will operate at approximately one-third to one-half of full power (800--1200 MW thermal) during this period and effluent temperatures will be substantially lower than earlier operation at full power. Monthly average discharge temperatures at half-power operation will range from approximately 42 degrees C in winter to 49 degrees C in summer. The volume of water discharged will not be affected by altered power levels and will average approximately 10--11 m 3 /s. The ecological consequences of this mode of operation on the Indian Grave/Pen Branch stream system have been evaluated

SU-E-T-48: A Multi-Institutional Study of Independent Dose Verification for Conventional, SRS and SBRT

International Nuclear Information System (INIS)

Takahashi, R; Kamima, T; Tachibana, H; Baba, H; Itano, M; Yamazaki, T; Ishibashi, S; Higuchi, Y; Shimizu, H; Yamamoto, T; Yamashita, M; Sugawara, Y; Sato, A; Nishiyama, S; Kawai, D; Miyaoka, S

2015-01-01

Purpose: To show the results of a multi-institutional study of the independent dose verification for conventional, Stereotactic radiosurgery and body radiotherapy (SRS and SBRT) plans based on the action level of AAPM TG-114. Methods: This study was performed at 12 institutions in Japan. To eliminate the bias of independent dose verification program (Indp), all of the institutions used the same CT-based independent dose verification software (Simple MU Analysis, Triangle Products, JP) with the Clarkson-based algorithm. Eclipse (AAA, PBC), Pinnacle 3 (Adaptive Convolve) and Xio (Superposition) were used as treatment planning system (TPS). The confidence limits (CL, Mean±2SD) for 18 sites (head, breast, lung, pelvis, etc.) were evaluated in comparison in dose between the TPS and the Indp. Results: A retrospective analysis of 6352 treatment fields was conducted. The CLs for conventional, SRS and SBRT were 1.0±3.7 %, 2.0±2.5 % and 6.2±4.4 %, respectively. In conventional plans, most of the sites showed within 5 % of TG-114 action level. However, there were the systematic difference (4.0±4.0 % and 2.5±5.8 % for breast and lung, respectively). In SRS plans, our results showed good agreement compared to the action level. In SBRT plans, the discrepancy between the Indp was variable depending on dose calculation algorithms of TPS. Conclusion: The impact of dose calculation algorithms for the TPS and the Indp affects the action level. It is effective to set the site-specific tolerances, especially for the site where inhomogeneous correction can affect dose distribution strongly

SU-E-T-48: A Multi-Institutional Study of Independent Dose Verification for Conventional, SRS and SBRT

Energy Technology Data Exchange (ETDEWEB)

Takahashi, R; Kamima, T [The Cancer Institute Hospital of JFCR, Koto-ku, Tokyo (Japan); Tachibana, H; Baba, H [National Cancer Center Hospital East, Kashiwa, Chiba (Japan); Itano, M; Yamazaki, T [Inagi Municipal Hospital, Inagi, Tokyo (Japan); Ishibashi, S; Higuchi, Y [Sasebo City General Hospital, Sasebo, Nagasaki (Japan); Shimizu, H [Kitasato University Medical Center, Kitamoto, Saitama (Japan); Yamamoto, T [Otemae Hospital, Chuou-ku, Osaka-city (Japan); Yamashita, M [Kobe City Medical Center General Hospital, Kobe, Hyogo (Japan); Sugawara, Y [The National Center for Global Health and Medicine, Shinjuku-ku, Tokyo (Japan); Sato, A [Itabashi Central General Hospital, Itabashi-ku, Tokyo (Japan); Nishiyama, S [Kuki General Hospital, Kuki, Saitama (Japan); Kawai, D [Kanagawa Cancer Center, Yokohama, Kanagawa-prefecture (Japan); Miyaoka, S [Kamitsuga General Hospital, Kanuma, Tochigi (Japan)

2015-06-15

Purpose: To show the results of a multi-institutional study of the independent dose verification for conventional, Stereotactic radiosurgery and body radiotherapy (SRS and SBRT) plans based on the action level of AAPM TG-114. Methods: This study was performed at 12 institutions in Japan. To eliminate the bias of independent dose verification program (Indp), all of the institutions used the same CT-based independent dose verification software (Simple MU Analysis, Triangle Products, JP) with the Clarkson-based algorithm. Eclipse (AAA, PBC), Pinnacle{sup 3} (Adaptive Convolve) and Xio (Superposition) were used as treatment planning system (TPS). The confidence limits (CL, Mean±2SD) for 18 sites (head, breast, lung, pelvis, etc.) were evaluated in comparison in dose between the TPS and the Indp. Results: A retrospective analysis of 6352 treatment fields was conducted. The CLs for conventional, SRS and SBRT were 1.0±3.7 %, 2.0±2.5 % and 6.2±4.4 %, respectively. In conventional plans, most of the sites showed within 5 % of TG-114 action level. However, there were the systematic difference (4.0±4.0 % and 2.5±5.8 % for breast and lung, respectively). In SRS plans, our results showed good agreement compared to the action level. In SBRT plans, the discrepancy between the Indp was variable depending on dose calculation algorithms of TPS. Conclusion: The impact of dose calculation algorithms for the TPS and the Indp affects the action level. It is effective to set the site-specific tolerances, especially for the site where inhomogeneous correction can affect dose distribution strongly.

Installation and operation of the Plantwide Fire Protection Systems and related Domestic Water Supply Systems

International Nuclear Information System (INIS)

1991-12-01

A safe work environment is needed to support the Savannah River Site (SRS) mission of producing special nuclear material. This Environmental Assessment (EA) assesses the potential environmental impact(s) of adding to and upgrading the Plantwide Fire Protection System and selected related portions of the Domestic Water Supply System at SRS, Aiken, South Carolina. The following objectives are expected to be met by this action: Prevent undue threat to public health and welfare from fire at SRS; prevent undue hazard to employees at SRS from fire; prevent unacceptable delay to vital DOE programs as a result of fire at SRS; keep fire related property damage at SRS to a manageable level;, and provide an upgraded supply of domestic water for the Reactor Areas. The Reactor Areas' domestic water supplies do not meet current demand capacity due to the age and condition of the 30-year old iron piping. In addition, the water quality for these supplies is not consistent with current SCDHEC requirements. Therefore, DOE proposes to upgrade this Domestic Water Supply System to meet current demand and quality levels, as well as the needs of fire protection system improvement

Integrated use of SRS Data &GIS Technique for Monitoring Changes in Riverine Forest of Sindh, Pakistan

Science.gov (United States)

Siddiqui, M.; Ali, Z.

Deforestation / depletion in forest area threaten the sustainability of agricultural production systems and en-danger the economy of the country. Every year extensive areas of arable agricultural and forestlands are degraded and turned into wastelands, due to natural causes or human interventions. There are several causes of deforestation, such as expansion in agricultural area, urban development, forest fires, commercial logging, illicit cutting, grazing, constructions of dams / reservoirs and barrages, com munication links, etc. Depletion in forest cover, therefore, has an important impact on socio - economic development and ecological balance. High population growth rate in Pakistan is one of the main causes for the rapid deterioration of physical environment and natural resource base. In view of this, it is felt necessary to carryout land -u s e studies focusing on strategies for mapping the past and present conditions and extent of forests and rangelands using Satellite Remote Sensing (SRS) data and GIS t echnology. The SRS and GIS technology provides a possible means of monitoring and mapping changes occurring in natural resources and the environment on a continuing basis. The riverine forests of Sindh mostly grow along the River Indus in the flood plains, spread over an area of 241,000 ha are disappearing very rapidly. Construction of dams / barrages on the upper reaches of the River Indus for hydroelectric power and irrigation works have significantly reduced the discharge of fresh water into the lower Indus basin and as a result, 100,000 acres of forests have disappeared. Furthermore, the heavy floods that occurred in 1978, 1988, 1992 and 1997, altered the course of the River Indus in many places, especially in the lower reaches, this has also damaged the riverine forests of Sindh. An integrated approach involving analysis of SRS data from 1977 to 1998 and GIS technique have been used to evaluate the geographic ex-tent and distribution of the riverine

SRS MOX fuel lead assemblies data report for the surplus plutonium disposition environmental impact statement

International Nuclear Information System (INIS)

O'Connor, D.G.; Fisher, S.E.; Holdaway, R.

1998-08-01

The purpose of this document is to support the US Department of Energy (DOE) Fissile Materials Disposition Program's preparation of the draft surplus plutonium disposition environmental impact statement. This is one of several responses to data call requests for background information on activities associated with the operation of the lead assembly (LA) mixed-oxide (MOX) fuel fabrication facility. DOE-MD requested that the DOE Site Operations Offices nominate DOE sites that meet established minimum requirements that could produce MOX LAs. Six initial site combinations were proposed: (1) Argonne National Laboratory-West (ANL-W) with support from Idaho National Engineering and Environmental Laboratory (INEEL), (2) Hanford, (3) Los Alamos National Laboratory (LANL) with support from Pantex, (4) Lawrence Livermore National Laboratory (LLNL), (5) Oak Ridge Reservation (ORR), and (6) Savannah River Site(SRS). After further analysis by the sites and DOE-MD, five site combinations were established as possible candidates for producing MOX LAs: (1) ANL-W with support from INEEL, (2) Hanford, (3) LANL, (4) LLNL, and (5) SRS. SRS has proposed an LA MOX fuel fabrication approach that would be done entirely inside an S and S Category 1 area. An alternate approach would allow fabrication of fuel pellets and assembly of fuel rods in an S and S Category 2 or 3 facility with storage of bulk PuO 2 and assembly, storage, and shipping of fuel bundles in an S and S Category 1 facility. The total Category 1 approach, which is the recommended option, would be done in the 221-H Canyon Building. A facility that was never in service will be removed from one area, and a hardened wall will be constructed in another area to accommodate execution of the LA fuel fabrication. The non-Category 1 approach would require removal of process equipment in the FB-Line metal production and packaging glove boxes, which requires work in a contamination area. The Immobilization Hot Demonstration Program

SRS MOX fuel lead assemblies data report for the surplus plutonium disposition environmental impact statement

Energy Technology Data Exchange (ETDEWEB)

O`Connor, D.G.; Fisher, S.E.; Holdaway, R. [and others

1998-08-01

The purpose of this document is to support the US Department of Energy (DOE) Fissile Materials Disposition Program`s preparation of the draft surplus plutonium disposition environmental impact statement. This is one of several responses to data call requests for background information on activities associated with the operation of the lead assembly (LA) mixed-oxide (MOX) fuel fabrication facility. DOE-MD requested that the DOE Site Operations Offices nominate DOE sites that meet established minimum requirements that could produce MOX LAs. Six initial site combinations were proposed: (1) Argonne National Laboratory-West (ANL-W) with support from Idaho National Engineering and Environmental Laboratory (INEEL), (2) Hanford, (3) Los Alamos National Laboratory (LANL) with support from Pantex, (4) Lawrence Livermore National Laboratory (LLNL), (5) Oak Ridge Reservation (ORR), and (6) Savannah River Site(SRS). After further analysis by the sites and DOE-MD, five site combinations were established as possible candidates for producing MOX LAs: (1) ANL-W with support from INEEL, (2) Hanford, (3) LANL, (4) LLNL, and (5) SRS. SRS has proposed an LA MOX fuel fabrication approach that would be done entirely inside an S and S Category 1 area. An alternate approach would allow fabrication of fuel pellets and assembly of fuel rods in an S and S Category 2 or 3 facility with storage of bulk PuO{sub 2} and assembly, storage, and shipping of fuel bundles in an S and S Category 1 facility. The total Category 1 approach, which is the recommended option, would be done in the 221-H Canyon Building. A facility that was never in service will be removed from one area, and a hardened wall will be constructed in another area to accommodate execution of the LA fuel fabrication. The non-Category 1 approach would require removal of process equipment in the FB-Line metal production and packaging glove boxes, which requires work in a contamination area. The Immobilization Hot Demonstration Program

Correlator filters for feedback at SRS and NSLS

International Nuclear Information System (INIS)

Dykes, D.M.; Galayda, J.N.

1987-01-01

In order to amplify signals that are produced by an oscillating beam, it is desirable to first reject that part of the signal produced when the beam is not oscillating. This can be done through the use of correlator filters which have the advantages of simplicity, at least 200 MHz working bandwidth, and broadband matching to 50 ohms at both input and output. Correlator filters have been built for the National Synchrotron Light Source (NSLS), the Daresbury SRS storage ring, and the NSLS x-ray ring. This report describes the performance of the filters and their associated electronic circuits. (FI)

Dismantlement and decontamination of a plutonium-238 facility at SRS

International Nuclear Information System (INIS)

Smith, R.H. Jr.; Hootman, H.E.

1994-01-01

There has been very little, documented decontamination and decommissioning (D ampersand D) experience on which to project cleanup costs and schedules for plutonium facilities at SRS and other DOE sites. A portion of the HB-Line, a plutonium-238 processing facility at SRS, has been undergoing D ampersand D intermittently since 1984. Although this cleanup effort was not originally intended to quantify results, some key data have been project has demonstrated effective methods of accumulated, and the performing D ampersand D work, and has demonstrated cleanup equipment and techniques under conditions of high contamination. Plutonium facilities where D ampersand D is already underway provide an opportunity for' timely field testing of characterization, size reduction, and decontamination techniques. Some data are presented here; however, more specific tests and data may be obtained during the remainder of this project. This project has been recommended as a candidate test facility for a DOE planned ''Integrated D ampersand D Demonstration'' managed by EM-50 to develop and demonstrate technology for D ampersand D and surplus facilities deactivation. Both the remainder of this project and the Integrated D ampersand D Demonstration Program can benefit from a joint effort, and the, overall costs should be reduced

Hanford Supplemental Treatment: Literature and Modeling Review of SRS HLW Salt Dissolution and Fractional Crystallization

Energy Technology Data Exchange (ETDEWEB)

Choi, A. S.; Flach, G. P.; Martino, C. J.; Zamecnik, J. R.; Harris, M. K.; Wilmarth, W. R.; Calloway, T. B.

2005-03-23

In order to accelerate waste treatment and disposal of Hanford tank waste by 2028, the Department of Energy (DOE) and CH2M Hill Hanford Group (CHG), Inc. are evaluating alternative technologies which will be used in conjunction with the Waste Treatment Plant (WTP) to safely pretreat and immobilize the tank waste. Several technologies (Bulk Vitrification and Steam Reforming) are currently being evaluated for immobilizing the pretreated waste. Since the WTP does not have sufficient capacity to pretreat all the waste going to supplemental treatment by the 2028 milestone, two technologies (Selective Dissolution and Fractional Crystallization) are being considered for pretreatment of salt waste. The scope of this task was to: (1) evaluate the recent Savannah River Site (SRS) Tank 41 dissolution campaign and other literature to provide a more complete understanding of selective dissolution, (2) provide an update on the progress of salt dissolution and modeling activities at SRS, (3) investigate SRS experience and outside literature sources on industrial equipment and experimental results of previous fractional crystallization processes, and (4) evaluate recent Hanford AP104 boildown experiments and modeling results and recommend enhancements to the Environmental Simulation Program (ESP) to improve its predictive capabilities. This report provides a summary of this work and suggested recommendations.

PILOT SCALE TESTING OF MONOSODIUM TITANATE MIXING FOR THE SRS SMALL COLUMN ION EXCHANGE PROCESS - 11224

Energy Technology Data Exchange (ETDEWEB)

Poirier, M.; Restivo, M.; Williams, M.; Herman, D.; Steeper, T.

2011-01-25

The Small Column Ion Exchange (SCIX) process is being developed to remove cesium, strontium, and select actinides from Savannah River Site (SRS) Liquid Waste using an existing waste tank (i.e., Tank 41H) to house the process. Savannah River National Laboratory (SRNL) is conducting pilot-scale mixing tests to determine the pump requirements for suspending monosodium titanate (MST), crystalline silicotitanate (CST), and simulated sludge. The purpose of this pilot scale testing is to determine the requirements for the pumps to suspend the MST particles so that they can contact the strontium and actinides in the liquid and be removed from the tank. The pilot-scale tank is a 1/10.85 linear scaled model of SRS Tank 41H. The tank diameter, tank liquid level, pump nozzle diameter, pump elevation, and cooling coil diameter are all 1/10.85 of their dimensions in Tank 41H. The pump locations correspond to the proposed locations in Tank 41H by the SCIX program (Risers B5 and B2 for two pump configurations and Risers B5, B3, and B1 for three pump configurations). The conclusions from this work follow: (i) Neither two standard slurry pumps nor two quad volute slurry pumps will provide sufficient power to initially suspend MST in an SRS waste tank. (ii) Two Submersible Mixer Pumps (SMPs) will provide sufficient power to initially suspend MST in an SRS waste tank. However, the testing shows the required pump discharge velocity is close to the maximum discharge velocity of the pump (within 12%). (iii) Three SMPs will provide sufficient power to initially suspend MST in an SRS waste tank. The testing shows the required pump discharge velocity is 66% of the maximum discharge velocity of the pump. (iv) Three SMPs are needed to resuspend MST that has settled in a waste tank at nominal 45 C for four weeks. The testing shows the required pump discharge velocity is 77% of the maximum discharge velocity of the pump. Two SMPs are not sufficient to resuspend MST that settled under these

Immunization of dogs with a canine herpesvirus vector expressing Neospora caninum surface protein, NcSRS2.

Science.gov (United States)

Nishikawa, Y; Ikeda, H; Fukumoto, S; Xuan, X; Nagasawa, H; Otsuka, H; Mikami, T

2000-10-01

In order to develop a vaccine against Neospora caninum in dogs, we constructed recombinant canine herpesvirus (CHV) expressing N. caninum surface protein, NcSRS2. Indirect immunofluorescence indicated that the antigenic structure of the recombinant NcSRS2 was similar to the authentic parasite protein. The dogs immunised with recombinant virus produced IgG antibody to N. caninum, and their sera recognised the parasite protein on Western blot. The dogs inoculated with recombinant virus showed no clinical symptoms and infectious CHV was not recovered from the dogs, suggesting that recombinant CHV expressing N. caninum proteins may lead to a vaccine against neosporosis in dogs.

Reliability and validity of adapted Turkish Version of Scoliosis Research Society-22 (SRS-22) questionnaire.

Science.gov (United States)

Alanay, Ahmet; Cil, Akin; Berk, Haluk; Acaroglu, R Emre; Yazici, Muharrem; Akcali, Omer; Kosay, Can; Genc, Yasemin; Surat, Adil

2005-11-01

Outcome study to determine the internal consistency, and validity of adapted Turkish version of Scoliosis Research Society-22 (SRS-22) Instrument. To evaluate the validity and reliability of adapted Turkish Version of SRS-22 questionnaire. The SRS-22 questionnaire is a widely accepted questionnaire to assess the health-related quality of life for scoliotic patients in the United States. However, its adaptation in languages other than the source language is necessary for its multinational use. Translation/retranslation of the English version of the SRS-22 was done, and all steps for cross-cultural adaptation process were performed properly by an expert committee. Later, SRS-22 questionnaires and previously validated Short Form-36 (SF-36) outcome instruments were mailed to 82 patients who had been surgically treated for idiopathic scoliosis. All patients had a minimum of 2 years follow-up. Fifty-four patients (66%) responded to the first set of questionnaires. Forty-seven of the first time respondents returned their second survey. The average age of the 47 patients (12 male, 35 female) was 19.8 years (range, 14-31 years). The two measures of reliability as internal consistency and reproducibility were determined by Cronbach alpha statistics and intraclass correlation coefficient, respectively. Concurrent validity was measured by comparing with an already validated questionnaire (SF-36). Measurement was made using the Pearson correlation coefficient (r). The study demonstrated satisfactory internal consistency with high Cronbach alpha values for the four of the corresponding domains (pain, 0.72; self-image, 0.80; mental health, 0.72; and satisfaction, 0.83). However, the Cronbach alpha value for function/activity domain (0.48) was considerably lower than the original questionnaire. The intraclass correlation coefficient for the same domains was 0.80, 0.82, 0.78, 0.81, and 0.76, respectively, demonstrating a satisfactory test/retest reproducibility. Considering

MAXDOSE-SR: A routine release atmospheric dose model used at SRS

International Nuclear Information System (INIS)

Simpkins, A.A.

2000-01-01

MAXDOSE-SR is a PC version of the dosimetry code MAXIGASP, which was used to calculate doses to the maximally exposed offsite individual for routine atmospheric releases of radioactive material at the Savannah River Site (SRS). Complete code description, verification of models, and user's manual have been included in this report. Minimal input is required to run the program, and site specific parameters are used when possible

Origins, and the construction, commissioning and operation of the SRS

International Nuclear Information System (INIS)

Thompson, D.J.

1985-01-01

The SRS was initiated in 1973 and approved in 1975. It came into use in 1981. The paper describes the organizational framework at the different stages, the pre-approval, construction, commissioning and operational phases of the storage ring, the build-up of experimental stations, and future plans. The emphasis is on lessons which can be learned by those about to embark on such a project, rather than on a detailed historical account, and on managerial rather than physics matters

SU-F-T-613: Multi-Lesion Cranial SRS VMAT Plan Quality

International Nuclear Information System (INIS)

Ballangrud, A; Kuo, L; Happersett, L; Lim, S; Li, X; Beal, K; Yamada, Y; LoSasso, T; Mechalakos, J

2016-01-01

Purpose: Cranial SRS VMAT plans must have steep dose gradient around each target to reduce dose to normal brain. This study reports on the correlation between gradient index (GI=V50%/V100%), target size and target dose heterogeneity index (HI=PTV Dmax/prescription dose) for multi-lesion cranial SRS VMAT plans. Methods: VMAT plans for 10 cranial cases with 3 to 6 lesions (total 39 lesions) generated in Varian Eclipse V11.0.47 with a fine-tuned AAA beam model and 0.125 cm dose grid were analyzed. One or two iso centers were used depending on the spatial distribution of lesions. Two to nine coplanar and non-coplanar arcs were used per isocenter. Conformity index (CI= V100%/VPTV), HI, and GI were determined for each lesion. Dose to critical structures were recorded. Results: Lesion size ranged from 0.05–11.00 cm3. HI ranged from 1.2–1.4, CI ranged from 1.0–2.8 and GI from 3.1–8.4. Maximum dose to brainstem, chiasm, lenses, optic nerves and eyes ranged from 120–1946 cGy, 47–463 cGy, 9–121 cGy, 14–512 cGy, and 17–294 cGy, respectively. Brain minus PTV (Brain-PTV) V7Gy was in the range 1.1–6.5%, and Brain-PTV Dmean was in the range 94–324 cGy. Conclusion: This work shows that a GI 0.4cc. For smaller lesions, GI increases rapidly. GI is lower when HI is increased. Based on this study, recommend HI is 1.4, and recommended GI is for volumes 1.0cc GI<4. CI is < 1.3 for all lesions except for targets < 0.1cc. Cranial SRS VMAT plans must be optimized to lower the GI to reduce the dose to normal brain tissue.

Test Review: "Social Responsiveness Scale" by J. N. Constantino and C. P. Gruber

Science.gov (United States)

Booker, Kimberly Wilson; Starling, LaRonda

2011-01-01

Published by Western Psychological Services, the "Social Responsiveness Scale" (SRS; Constantino & Gruber, 2005) was designed to assess abilities and deficits in social reciprocity. In particular, it was designed to assess subthreshold levels and severity of social impairment, a key marker of pervasive developmental disorders. The SRS may be…

HRQoL assessment by SRS-30 for Chinese patients with surgery for Adolescent Idiopathic Scoliosis (AIS).

Science.gov (United States)

Ng, Bobby Kin Wah; Chau, Wai-Wang; Hui, Chak-Na; Cheng, Po-Yin; Wong, Chau-Yuet; Wang, Bin; Cheng, Jack Chun Yiu; Lam, Tsz Ping

2015-01-01

Health-related quality of life (HRQoL) outcome questionnaire, Scoliosis Research Society (SRS)-30, had been well received since its establishment in 2003. Literatures from Asia on the use of SRS-30 mainly focused on the translation process and validation process, but not on measuring outcomes, particularly in the Chinese community. We carried out a prospective cohort study to evaluate the HRQoL of Chinese AIS adolescents with severe scoliosis after surgery. One hundred and four Chinese AIS patients with severe scoliosis undergoing posterior spinal fusion between 2009 and 2013 were recruited in this study. They completed SRS-30 questions before surgery, before hospital discharge, and at follow-up. Mean scores and percentages of individual scores in different domains, and composite scores in terms of subtotal and total scores were calculated referring to the scoring system. Gender-specific and period-specific descriptive analyses were described. Correlation of mean domain scores at the three time points were explored to look for any time-specific relationship. Linear regression analysis looking for potential risk factors on domain scores at different time points by gender were also carried out. Mean age was 16.28 at surgery, and 83.6% were female. Significant correlations between pre-op scores and scores after surgery were observed in function/activity domain (p=0.05) in males, and pain (p=0.04) and satisfaction with management (p=0.04) domains in females. No gender difference in all 5 domain scores at the 3 time points was found. Pre-op maximum Cobb angle and corrected angle were found to be risk factors on self-image, as well as satisfaction with management, in male and female patients. This is the first report on the evaluation of the clinical HRQoL outcomes of Chinese AIS patients with severe scoliosis after surgery. Medical professionals should pay attention to take care of the difference in personal perceptions of feelings between boys and girls. Special care

Savannah River Site management response plan for chemical safety vulnerability field assessment. Revision 1

International Nuclear Information System (INIS)

Kahal, E.J.; Murphy, S.L.; Salaymeh, S.R.

1994-09-01

As part of the U.S. Department of Energy's (DOE) initiative to identify potential chemical safety vulnerabilities in the DOE complex, the Chemical Safety Vulnerability Core Working Group issued a field verification assessment report. While the report concluded that Savannah River Site (SRS) is moving in a positive direction, the report also identified five chemical safety vulnerabilities with broad programmatic impact that are not easily nor quickly remedied. The May 1994 SRS Management Response Plan addressed the five SRS vulnerabilities identified in the field assessment report. The SRS response plan listed observations supporting the vulnerabilities and any actions taken or planned toward resolution. Many of the observations were resolved by simple explanations, such as the existence of implementation plans for Safety Analysis Report updates. Recognizing that correcting individual observations does not suffice in remedying the vulnerabilities, a task team was assembled to address the broader programmatic issues and to recommend corrective actions

WASTE MANAGEMENT AT SRS - MAKING IT HAPPEN

International Nuclear Information System (INIS)

Heenan, T. F.; Kelly, S.

2002-01-01

The past five years have witnessed a remarkable transition in the pace and scope of waste management activities at SRS. At the start of the new M and O contract in 1996, little was being done with the waste generated at the site apart from storing it in readiness for future treatment and disposal. Large volumes of legacy waste, particularly TRU and Low Level Waste, had accumulated over many years of operation of the site's nuclear facilities, and the backlog was increasing. WSRC proposed the use of the talents of the ''best in class'' partners for the new contract which, together with a more commercial approach, was expected to deliver more results without a concomitant increase in cost. This paper charts the successes in the Solid Waste arena and analyzes the basis for success

The Social Responsiveness Scale in relation to DSM IV and DSM5 ASD in Korean Children

Science.gov (United States)

Cheon, Keun-Ah; Park, Jee-In; Koh, Yun-Joo; Song, Jungeun; Hong, Hyun-Joo; Kim, Young-Kee; Lim, Eun-Chung; Kwon, Hojang; Ha, Mina; Lim, Myung-Ho; Paik, Ki-Chung; Constantino, John N.; Leventhal, Bennett; Kim, Young Shin

2017-01-01

LAY ABSTRACT The Social Responsiveness Scale(SRS) is an autism rating scales in widespread use, with over 20 official foreign language translations. It has proven highly feasible for quantitative ascertainment of autistic social impairment in public health settings, however, little is known about the validity of the reinforcement in Asia populations or in references to DSM5. The current study aims to evaluate psychometric properties and cross-cultural aspects of the SRS-Korean version (K-SRS). Our results indicate that the K-SRS exhibits adequate reliability and validity for measuring Autism Spectrum Disorder (ASD) symptoms in Korean children with DSM IV PDD and DSM5 ASD. Our findings further suggest that it is difficult to distinguish Social Communication Disorder (SCD) from other child psychiatric conditions using the K-SRS. This is the first study to examine the relationship between the SRS subscales and DSM5 based clinical diagnosis. This study provides cross-cultural confirmation of the factor structure of ASD symptoms and traits measured by the SRS. SCIENTIFIC ABSTRACT The Social Responsiveness Scale(SRS) is an autism rating scales in widespread use, with over 20 official foreign language translations. It has proven highly feasible for quantitative ascertainment of autistic social impairment in public health settings, however, little is known about the validity of the reinforcement in Asia populations or in references to DSM5. The current study aims to evaluate psychometric properties and cross-cultural aspects of the SRS-Korean version(K-SRS). The study subjects were ascertained from three samples: a general sample from 3 regular education elementary schools(n=790), a clinical sample(n=154) of 6–12-year-olds from four psychiatric clinics, and an epidemiological sample of children with ASD, diagnosed using both DSM IV PDD, DSM5 ASD and SCD criteria(n=151). Their parents completed the K-SRS and the Autism Spectrum Screening Questionnaire(ASSQ). Descriptive

Stereotactic Radiosurgery: Treatment of Brain Metastasis Without Interruption of Systemic Therapy

Energy Technology Data Exchange (ETDEWEB)

Shen, Colette J.; Kummerlowe, Megan N.; Redmond, Kristin J. [Department of Radiation Oncology, Johns Hopkins Hospital, Baltimore, Maryland (United States); Rigamonti, Daniele [Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland (United States); Johns Hopkins Aramco Healthcare, Dhahran (Saudi Arabia); Lim, Michael K. [Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland (United States); Kleinberg, Lawrence R., E-mail: kleinla@jhmi.edu [Department of Radiation Oncology, Johns Hopkins Hospital, Baltimore, Maryland (United States)

2016-06-01

Purpose: To evaluate the prevalence, outcomes, and toxicities of concurrent delivery of systemic therapy with stereotactic radiosurgery (SRS) for treatment of brain metastases. Methods and Materials: We conducted a retrospective review of 193 patients treated at our institution with SRS without prior whole-brain radiation therapy (WBRT) for brain metastases between 2009 and 2014. Outcome metrics included administration of concurrent systemic therapy, myelosuppression, neurotoxicity, and survival. Results: One hundred ninety-three patients with a median age of 61 years underwent a total of 291 SRS treatments. Thirty-seven percent of SRS treatments were delivered concurrently with systemic therapy, of which 46% were with conventional myelosuppressive chemotherapy, and 54% with targeted and immune therapy agents. Myelosuppression was minimal after treatment with both systemic therapy and SRS, with 14% grade 3-4 toxicity for lymphopenia and 4-9% for leukopenia, neutropenia, anemia, and thrombocytopenia. Neurotoxicity was also minimal after combined therapy, with no grade 4 and <5% grade 3 toxicity, 34% dexamethasone requirement, and 4% radiation necrosis, all similar to treatments with SRS alone. Median overall survival was similar after SRS alone (14.4 months) versus SRS with systemic therapy (12.9 months). In patients with a new diagnosis of primary cancer with brain metastasis, early treatment with concurrent systemic therapy and SRS correlated with improved survival versus SRS alone (41.6 vs 21.5 months, P<.05). Conclusions: Systemic therapy can be safely given concurrently with SRS for brain metastases: our results suggest minimal myelosuppression and neurotoxicity. Concurrent therapy is an attractive option for patients who have both intracranial and extracranial metastatic disease and may be particularly beneficial in patients with a new diagnosis of primary cancer with brain metastasis.

Reliability and concurrent validity of the adapted Chinese version of Scoliosis Research Society-22 (SRS-22) questionnaire.

Science.gov (United States)

Cheung, Kenneth M C; Senkoylu, Alpaslan; Alanay, Ahmet; Genc, Yasemin; Lau, Sarah; Luk, Keith D

2007-05-01

Validation study to define validity and reliability of an adapted and translated questionnaire. Assessment of the concurrent validity and reliability of a Chinese version of SRS-22 outcome instrument. No valid health-related quality of life (HRQL) outcome instrument exists for patients with spinal deformity in Chinese. The modified SRS-22 questionnaire was proven to be an appropriate outcome instrument in English, and has already been translated and validated in several other languages. The English version of the SRS-22 questionnaire was adapted to Chinese according to the International Quality of Life Assessment Project guidelines. To assess reliability, 48 subjects with adolescent idiopathic scoliosis (mean age, 16.5 years) filled the questionnaire on 2 separate occasions (Group 1). To assess concurrent validity, 50 subjects (mean age, 21 years) filled in the same questionnaire and a previously validated Chinese version of the Short Form-36 (SF36) questionnaire (Group 2). Internal consistency, reproducibility and concurrent validity were determined with Cronbach's alpha coefficient, interclass correlation coefficient and Pearson correlation coefficient, respectively. Cronbach's alpha coefficient for the 4 major domains (function/activity, pain, self-image/appearance and mental health) were high. Intraclass correlation was also excellent for all domains. For concurrent validity, excellent correlation was found in 1 domain, good in 12 domains, moderate in 3 domains, and poor in 1 domain of the 17 relevant domains. Both cultural adaptation and linguistic translation are essential in any attempt to use a HRQL questionnaire across cultures. The Chinese version of the SRS-22 outcome instrument has satisfactory internal consistency and excellent reproducibility. It is ready for use in clinical studies on idiopathic scoliosis in Chinese-speaking societies.

Optimal replacement policy for safety-related multi-component multi-state systems

International Nuclear Information System (INIS)

Xu Ming; Chen Tao; Yang Xianhui

2012-01-01

This paper investigates replacement scheduling for non-repairable safety-related systems (SRS) with multiple components and states. The aim is to determine the cost-minimizing time for replacing SRS while meeting the required safety. Traditionally, such scheduling decisions are made without considering the interaction between the SRS and the production system under protection, the interaction being essential to formulate the expected cost to be minimized. In this paper, the SRS is represented by a non-homogeneous continuous time Markov model, and its state distribution is evaluated with the aid of the universal generating function. Moreover, a structure function of SRS with recursive property is developed to evaluate the state distribution efficiently. These methods form the basis to derive an explicit expression of the expected system cost per unit time, and to determine the optimal time to replace the SRS. The proposed methodology is demonstrated through an illustrative example.

Breeding bird populations and habitat associations within the Savannah River Site (SRS).

Energy Technology Data Exchange (ETDEWEB)

Gauthreaux, Sidney, A.; Steven J. Wagner.

2005-06-29

Gauthreaux, Sidney, A., and Steven J. Wagner. 2005. Breeding bird populations and habitat associations within the Savannah River Site (SRS). Final Report. USDA Forest Service, Savannah River, Aiken, SC. 48 pp. Abstract: During the 1970's and 1980's a dramatic decline occurred in the populations of Neotropical migratory birds, species that breed in North America and winter south of the border in Central and South America and in the Caribbean. In 1991 an international initiative was mounted by U. S. governmental land management agencies, nongovernmental conservation agencies, and the academic and lay ornithological communities to understand the decline of Neotropical migratory birds in the Americas. In cooperation with the USDA Forest Service - Savannah River (FS - SR) we began 1992 a project directed to monitoring population densities of breeding birds using the Breeding Bird Census (BBC) methodology in selected habitats within the Savannah River Site SRS. In addition we related point count data on the occurrence of breeding Neotropical migrants and other bird species to the habitat data gathered by the Forest Inventory and Analysis (FIA) program of the USDA Forest Service and data on habitat treatments within forest stands.

Receipt capability for foreign research reactor (FRR) spent nuclear fuel (SNF) at the Savannah River Site (SRS)

International Nuclear Information System (INIS)

Clark, William D. Jr.

1997-01-01

The United Stated Department of Energy began implementation of the ten year FRR SNF return policy in May, 1996. Seventeen months into the thirteen year return program, four shipments have been made, returning 863 assemblies of aluminum clad SNF to SRS. Five additional shipments containing over 1,200 assemblies are scheduled in fiscal year 1998. During negotiation of contracts with various reactor operators, it has become apparent that many facilities wish to delay the return of their SNF until the latter part of the program. This has raised concern on the part of the DOE that insufficient receipt capability will exist during the last three to five years of the program to ensure the return of all of the SNF. To help quantify this issue and ensure that it is addressed early in the program, a computer simulation model has been developed at SRS to facilitate the planning, scheduling, and analysis of SNF shipments to be received from offsite facilities. The simulation model, called OFFSHIP, greatly reduces the time and effort required to analyze the complex global transportation system that involves dozens of reactor facilities, multiple casks and fuel types, and time-dependent SNF inventories. OFFSHIP allows the user to input many variables including priorities, cask preferences, shipping date preferences, turnaround times, and regional groupings. User input is easily managed using a spreadsheet format and the output data is generated in a spreadsheet format to facilitate detailed analysis and prepare graphical results. The model was developed in Microsoft Visual Basic for Applications and runs native in Microsoft Excel. The receipt schedules produced by the model have been compared to schedules generated manually with consistent results. For the purposes of this presentation, four scenarios have been developed. The 'Base Case' accounts for those countries/facilities that DOE believes may not participate in the return program. The three additional scenarios look at the

SU-F-T-613: Multi-Lesion Cranial SRS VMAT Plan Quality

Energy Technology Data Exchange (ETDEWEB)

Ballangrud, A; Kuo, L; Happersett, L; Lim, S; Li, X; Beal, K; Yamada, Y; LoSasso, T; Mechalakos, J [Memorial Sloan-Kettering Cancer Center, New York, NY (United States)

2016-06-15

Purpose: Cranial SRS VMAT plans must have steep dose gradient around each target to reduce dose to normal brain. This study reports on the correlation between gradient index (GI=V50%/V100%), target size and target dose heterogeneity index (HI=PTV Dmax/prescription dose) for multi-lesion cranial SRS VMAT plans. Methods: VMAT plans for 10 cranial cases with 3 to 6 lesions (total 39 lesions) generated in Varian Eclipse V11.0.47 with a fine-tuned AAA beam model and 0.125 cm dose grid were analyzed. One or two iso centers were used depending on the spatial distribution of lesions. Two to nine coplanar and non-coplanar arcs were used per isocenter. Conformity index (CI= V100%/VPTV), HI, and GI were determined for each lesion. Dose to critical structures were recorded. Results: Lesion size ranged from 0.05–11.00 cm3. HI ranged from 1.2–1.4, CI ranged from 1.0–2.8 and GI from 3.1–8.4. Maximum dose to brainstem, chiasm, lenses, optic nerves and eyes ranged from 120–1946 cGy, 47–463 cGy, 9–121 cGy, 14–512 cGy, and 17–294 cGy, respectively. Brain minus PTV (Brain-PTV) V7Gy was in the range 1.1–6.5%, and Brain-PTV Dmean was in the range 94–324 cGy. Conclusion: This work shows that a GI < 5 can be achieved for lesions > 0.4cc. For smaller lesions, GI increases rapidly. GI is lower when HI is increased. Based on this study, recommend HI is 1.4, and recommended GI is for volumes <0.1cc GI<9, 0.1–0.4cc GI<6, 0.4–0.1.0cc GI<5, and for volumes >1.0cc GI<4. CI is < 1.3 for all lesions except for targets < 0.1cc. Cranial SRS VMAT plans must be optimized to lower the GI to reduce the dose to normal brain tissue.

Progress in the environmental restoration at the Savannah River Site (SRS)

International Nuclear Information System (INIS)

Pope, J.M.; McClain, L.

1992-01-01

The Environmental Restoration (ER) Program has continued to achieve significant accomplishments important to the mission of cleaning up inactive waste sites, performing corrective actions on contaminated groundwater, planning for decontaminating/decommissioning surplus facilities and ensuring that the environment and the health and safety of people are protected. The multifaceted cleanup at SRS represents noteworthy milestones across the DOE complex. The associated lessons learned and key elements of the progress will be presented in the course of the paper

SRS SLUDGE BATCH QUALIFICATION AND PROCESSING; HISTORICAL PERSPECTIVE AND LESSONS LEARNED

Energy Technology Data Exchange (ETDEWEB)

Cercy, M.; Peeler, D.; Stone, M.

2013-09-25

This report provides a historical overview and lessons learned associated with the SRS sludge batch (SB) qualification and processing programs. The report covers the framework of the requirements for waste form acceptance, the DWPF Glass Product Control Program (GPCP), waste feed acceptance, examples of how the program complies with the specifications, an overview of the Startup Program, and a summary of continuous improvements and lessons learned. The report includes a bibliography of previous reports and briefings on the topic.

Trends in Attendance at Scoliosis Research Society Annual Meetings (SRS AM) and International Meeting on Advanced Spine Techniques (IMAST): Location, Location, Location.

Science.gov (United States)

Chen, Foster; Cho, Woojin; Kim, Han Jo; Levine, David B

2017-07-01

Descriptive, respective. Although overall membership in Scoliosis Research Society (SRS) has grown over the years, we were curious to see the effects of changing event venue location and timing on conference attendance. Every year, the SRS hosts two major meetings: the Annual Meeting (SRS AM) in the autumn, and the International Meeting on Advanced Spine Techniques (IMAST) in the summer. Sites have alternated from within and outside North America. Often, these meetings have also overlapped with several holidays in certain countries. This was an observational study of attendance from past SRS AM and IMAST meetings. Fourteen years of AM and 8 years of IMAST data were made available from the SRS. Participation based on delegate type and countries were tallied. Details from the 10 most represented nations and host nations per year were also tallied, and their national holidays were reviewed for overlaps with the AM. Membership in AM and IMAST increased from 820 in 2003 to 1,323 in 2016. Attendance at the AM has increased, whereas attendance at IMAST has declined, even after adjusting for membership size. Trends in participation were highly influenced by location. Participation by attendees from the host continent, and especially the host country, is generally high. The negative impact of distant meetings is profoundly seen with North Americans, whereas the positive impact of a nearby meeting was mostly clearly demonstrated by South Americans. Although SRS AM overlapped with holidays in China, Japan, or Korea nearly 50% of the time, this did not influence participation by delegates from these countries. Participation in the AM is highly influenced by location. Although North Americans represented the largest constituency, their presence was not needed to drive total attendance and was not sufficient to turn around the downturn in IMAST attendance. Choice of location can encourage the participation of delegates from the host and neighboring nations; through strategic

Commercial Submersible Mixing Pump For SRS Tank Waste Removal - 15223

International Nuclear Information System (INIS)

Hubbard, Mike; Herbert, James E.; Scheele, Patrick W.

2015-01-01

The Savannah River Site Tank Farms have 45 active underground waste tanks used to store and process nuclear waste materials. There are 4 different tank types, ranging in capacity from 2839 m 3 to 4921 m 3 (750,000 to 1,300,000 gallons). Eighteen of the tanks are older style and do not meet all current federal standards for secondary containment. The older style tanks are the initial focus of waste removal efforts for tank closure and are referred to as closure tanks. Of the original 51 underground waste tanks, six of the original 24 older style tanks have completed waste removal and are filled with grout. The insoluble waste fraction that resides within most waste tanks at SRS requires vigorous agitation to suspend the solids within the waste liquid in order to transfer this material for eventual processing into glass filled canisters at the Defense Waste Processing Facility (DWPF). SRS suspends the solid waste by use of recirculating mixing pumps. Older style tanks generally have limited riser openings which will not support larger mixing pumps, since the riser access is typically 58.4 cm (23 inches) in diameter. Agitation for these tanks has been provided by four long shafted standard slurry pumps (SLP) powered by an above tank 112KW (150 HP) electric motor. The pump shaft is lubricated and cooled in a pressurized water column that is sealed from the surrounding waste in the tank. Closure of four waste tanks has been accomplished utilizing long shafted pump technology combined with heel removal using multiple technologies. Newer style waste tanks at SRS have larger riser openings, allowing the processing of waste solids to be accomplished with four large diameter SLPs equipped with 224KW (300 HP) motors. These tanks are used to process the waste from closure tanks for DWPF. In addition to the SLPs, a 224KW (300 HP) submersible mixer pump (SMP) has also been developed and deployed within older style tanks. The SMPs are product cooled and product lubricated canned

Stochastic shock response spectrum decomposition method based on probabilistic definitions of temporal peak acceleration, spectral energy, and phase lag distributions of mechanical impact pyrotechnic shock test data

Science.gov (United States)

Hwang, James Ho-Jin; Duran, Adam

2016-08-01

Most of the times pyrotechnic shock design and test requirements for space systems are provided in Shock Response Spectrum (SRS) without the input time history. Since the SRS does not describe the input or the environment, a decomposition method is used to obtain the source time history. The main objective of this paper is to develop a decomposition method producing input time histories that can satisfy the SRS requirement based on the pyrotechnic shock test data measured from a mechanical impact test apparatus. At the heart of this decomposition method is the statistical representation of the pyrotechnic shock test data measured from the MIT Lincoln Laboratory (LL) designed Universal Pyrotechnic Shock Simulator (UPSS). Each pyrotechnic shock test data measured at the interface of a test unit has been analyzed to produce the temporal peak acceleration, Root Mean Square (RMS) acceleration, and the phase lag at each band center frequency. Maximum SRS of each filtered time history has been calculated to produce a relationship between the input and the response. Two new definitions are proposed as a result. The Peak Ratio (PR) is defined as the ratio between the maximum SRS and the temporal peak acceleration at each band center frequency. The ratio between the maximum SRS and the RMS acceleration is defined as the Energy Ratio (ER) at each band center frequency. Phase lag is estimated based on the time delay between the temporal peak acceleration at each band center frequency and the peak acceleration at the lowest band center frequency. This stochastic process has been applied to more than one hundred pyrotechnic shock test data to produce probabilistic definitions of the PR, ER, and the phase lag. The SRS is decomposed at each band center frequency using damped sinusoids with the PR and the decays obtained by matching the ER of the damped sinusoids to the ER of the test data. The final step in this stochastic SRS decomposition process is the Monte Carlo (MC

SU-E-J-221: Advantages of a New Surface Imaging Calibration Method for SRS Treatments

International Nuclear Information System (INIS)

Paxton, A; Manger, R; Pawlicki, T; Kim, G

2014-01-01

Purpose: The present calibration method used for the AlignRT surface imaging system relies on the placement of a calibration plate at the linac isocenter using isocenter surrogates (crosshairs, room lasers, etc.). This work investigated the potential advantages of a new calibration method that shifts the AlignRT isocenter to be coincident with the linac MV beam isocenter. Methods: To quantify the potential uncertainties associated with the present calibration method for SRS treatments, the calibration plate was intentionally shifted away from isocenter +/−3mm in the longitudinal and lateral directions and +/−1mm in the longitudinal, lateral, and vertical directions. A head phantom was placed in a mock SRS treatment position and monitored with the AlignRT system. The AlignRT-indicated offsets were recorded at 270, 315, 0, 45, and 90° couch angles for each intentional calibration misalignment. The new isocenter calibration was applied after each misalignment, and the measurements were repeated and compared to the previous results. Results: With intentional longitudinal and lateral shifts of +/−3mm and +/−1mm in the calibration plate, the average indicated offsets at couch rotations of +/−90° were 4.3mm and 1.6mm, respectively. This was in agreement with the theoretical offset of sqrt(2)*(intentional shift of the calibration plate). Since vertical shifts were along the rotation axis of the couch, these shifts had little effect on the offsets with changing couch angle. When the new calibration was applied, the indicated offsets were all within 0.5mm for all couch angles. These offsets were in agreement with the known magnitude of couch walkout. Conclusion: The potential pitfalls of the present calibration method have been established, and the advantages of the new calibration method have been demonstrated. This new calibration method effectively removes the potential miscalibration artifacts of the present calibration method, giving the AlignRT user more

SRL in-situ tests in the United Kingdom: Part 2, Surface analyses of SRS waste glass buried for one and two years in limestone at Ballidon, UK

International Nuclear Information System (INIS)

Namboodri, C.G. Jr.; Wicks, G.G.

1991-01-01

A multiphase experimental program to assess and understand waste glass behavior under a wide range of conditions has been in progress at the Savannah River Laboratory (SRL) for over a decade. An important part of this experimental effort is to assess the effects of repository relevant conditions on performance of SRS waste glass, in both controlled laboratory tests, as well as in actual field experiments. In laboratory test, SRS waste glass, simulated and in many cases also fully radioactive, has been tested in environments of salt, basalt, shale, granite, clay and tuff. In field experiments, there are four joint international programs being conducted in four different countries, involving burial of SRS simulated waste glass in granite, limestone, clay and salt geologies. This report discusses the SRS waste glass studies in limestone at Ballidon, UK

A Comprehensive Analysis of the SRS-Schwab Adult Spinal Deformity Classification and Confounding Variables: A Prospective, Non-US Cross-sectional Study in 292 Patients.

Science.gov (United States)

Hallager, Dennis Winge; Hansen, Lars Valentin; Dragsted, Casper Rokkjær; Peytz, Nina; Gehrchen, Martin; Dahl, Benny

2016-05-01

Cross-sectional analyses on a consecutive, prospective cohort. To evaluate the ability of the Scoliosis Research Society (SRS)-Schwab Adult Spinal Deformity Classification to group patients by widely used health-related quality-of-life (HRQOL) scores and examine possible confounding variables. The SRS-Schwab Adult Spinal Deformity Classification includes sagittal modifiers considered important for HRQOL and the clinical impact of the classification has been validated in patients from the International Spine Study Group database; however, equivocal results were reported for the Pelvic Tilt modifier and potential confounding variables were not evaluated. Between March 2013 and May 2014, all adult spinal deformity patients from our outpatient clinic with sufficient radiographs were prospectively enrolled. Analyses of HRQOL variance and post hoc analyses were performed for each SRS-Schwab modifier. Age, history of spine surgery, and aetiology of spinal deformity were considered potential confounders and their influence on the association between SRS-Schwab modifiers and aggregated Oswestry Disability Index (ODI) scores was evaluated with multivariate proportional odds regressions. P values were adjusted for multiple testing. Two hundred ninety-two of 460 eligible patients were included for analyses. The SRS-Schwab Classification significantly discriminated HRQOL scores between normal and abnormal sagittal modifier classifications. Individual grade comparisons showed equivocal results; however, Pelvic Tilt grade + versus +  + did not discriminate patients according to any HRQOL score. All modifiers showed significant proportional odds for worse aggregated ODI scores with increasing grade levels and the effects were robust to confounding. However, age group and aetiology had individual significant effects. The SRS-Schwab sagittal modifiers reliably grouped patients graded 0 versus + / +  + according to the most widely used HRQOL scores and the

Development of a new physics data library for the SRS reactors

International Nuclear Information System (INIS)

Niemer, K.A.

1993-01-01

The Savannah River Site (SRS) reactors have historically operated at power levels of -2500 MW; thus, previous reactor physics data libraries were created based on that constant power. However, as a result of recent lower power operation, the existing physics data libraries are no longer adequate. Therefore, a new power-dependent physics library was needed to model the reactor at different power levels. The design and development of a new power-dependent physics data library is discussed in this paper

Combining stereotactic radiosurgery and systemic therapy for brain metastases: a potential role for temozolomide

Energy Technology Data Exchange (ETDEWEB)

Hardee, Matthew E. [Department of Radiation Oncology, New York University Langone Medical Center, New York, NY (United States); Formenti, Silvia C., E-mail: silvia.formenti@nyumc.org [Department of Radiation Oncology, New York University Langone Medical Center, New York, NY (United States); Department of Medical Oncology, New York University Langone Medical Center, New York, NY (United States)

2012-08-09

Brain metastases are unfortunately very common in the natural history of many solid tumors and remain a life-threatening condition, associated with a dismal prognosis, despite many clinical trials aimed at improving outcomes. Radiation therapy options for brain metastases include whole brain radiotherapy (WBRT) and stereotactic radiosurgery (SRS). SRS avoids the potential toxicities of WBRT and is associated with excellent local control (LC) rates. However, distant intracranial failure following SRS remains a problem, suggesting that untreated intracranial micrometastatic disease is responsible for failure of treatment. The oral alkylating agent temozolomide (TMZ), which has demonstrated efficacy in primary malignant central nervous system tumors such as glioblastoma, has been used in early phase trials in the treatment of established brain metastases. Although results of these studies in established, macroscopic metastatic disease have been modest at best, there is clinical and preclinical data to suggest that TMZ is more efficacious at treating and controlling clinically undetectable intracranial micrometastatic disease. We review the available data for the primary management of brain metastases with SRS, as well as the use of TMZ in treating established brain metastases and undetectable micrometastatic disease, and suggest the role for a clinical trial with the aims of treating macroscopically visible brain metastases with SRS combined with TMZ to address microscopic, undetectable disease.

Scoliosis Research Society (SRS) Criteria and Society of Scoliosis Orthopaedic and Rehabilitation Treatment (SOSORT) 2008 Guidelines in Non-Operative Treatment of Idiopathic Scoliosis.

Science.gov (United States)

Korbel, Krzysztof; Kozinoga, Mateusz; Stoliński, Łukasz; Kotwicki, Tomasz

2014-07-28

According to the Scoliosis Research Society (SRS), idiopathic scoliosis (IS) is a curvature of more than 10° Cobb angle, affecting 2-3% of pediatric population. Idiopathic scoliosis accounts for 80% of all scoliosis cases. Non-operative principles in the therapy of idiopathic scoliosis, including Scoliosis Research Society (SRS) criteria and guidelines proposed by the experts of the Society on Scoliosis Orthopedic and Rehabilitation Treatment (SOSORTS) were presented. The possibility to carry out quality of life assessments in a conservative procedure was also demonstrated. Based on the natural history of idiopathic scoliosis, SRS criteria, SOSORT 2008 experts' opinion and the knowledge of the possibilities of psychological assessment of conservative IS treatment, rules were proposed regarding nonsurgical IS therapy procedures, with special consideration being paid to the proper treatment start time (age, Risser test, biological maturity, Cobb angle), possibility of curvature progression, the importance of physiotherapy and psychological assessment. The knowledge of SRS criteria and SOSORT guidelines regarding the conservative treatment of IS are essential for proper treatment (the right time to start treatment), and supports establishment of interdisciplinary treatment teams, consisting of a physician, a physiotherapist, an orthopedic technician and a psychologist.

Thirty-year solid waste generation forecast for facilities at SRS

International Nuclear Information System (INIS)

1994-07-01

The information supplied by this 30-year solid waste forecast has been compiled as a source document to the Waste Management Environmental Impact Statement (WMEIS). The WMEIS will help to select a sitewide strategic approach to managing present and future Savannah River Site (SRS) waste generated from ongoing operations, environmental restoration (ER) activities, transition from nuclear production to other missions, and decontamination and decommissioning (D ampersand D) programs. The EIS will support project-level decisions on the operation of specific treatment, storage, and disposal facilities within the near term (10 years or less). In addition, the EIS will provide a baseline for analysis of future waste management activities and a basis for the evaluation of the specific waste management alternatives. This 30-year solid waste forecast will be used as the initial basis for the EIS decision-making process. The Site generates and manages many types and categories of waste. With a few exceptions, waste types are divided into two broad groups-high-level waste and solid waste. High-level waste consists primarily of liquid radioactive waste, which is addressed in a separate forecast and is not discussed further in this document. The waste types discussed in this solid waste forecast are sanitary waste, hazardous waste, low-level mixed waste, low-level radioactive waste, and transuranic waste. As activities at SRS change from primarily production to primarily decontamination and decommissioning and environmental restoration, the volume of each waste s being managed will change significantly. This report acknowledges the changes in Site Missions when developing the 30-year solid waste forecast

SRS-sensor 13C/12C isotops measurements for detecting Helicobacter Pylori

Science.gov (United States)

Grishkanich, Aleksandr; Chubchenko, Yan; Elizarov, Valentin; Zhevlakov, Aleksandr; Konopelko, Leonid

2018-02-01

We developed SRS-sensor 13C/12C isotops measurements detecting Helicobacter Pylori for medical diagnostics of human health. Measuring of absolute 13C/12C isotope amount ratios allows to explore the topical problems of the modern world, alcoholic beverages and tobacco, medical diagnostics of human health. SRS method is used to measure the ratio of carbon isotopes in the exhaled carbon dioxide, which is used to diagnose the human infection of Helicobacter pylori and the influence of the Helicobacter pylori bacterium on the occurrence of gastritis, gastric and duodenal ulcers. A method for the analysis of human infection with Helicobacter pylori was developed on the basis of measurements of the ratio of 13C / 12C carbon isotopes in human exhaled air with a high level of measurement accuracy. The article reviews the work in the field of provision comparability of absolute 13C/12C isotope amount ratios in the environment and food. The analysis of the technical and metrological characteristics of traditional and perspective instruments for measuring isotope ratios is presented. The provision of comparability of absolute 13C/12C isotope amount ratios is carried by gravimetrically prepared reference standards. The key features and emerging issues are discussed.

Citizen Contributions to the Closure of High-Level Waste (HLW) Tanks 18 and 19 at the Department of Energy's (DOE) Savannah River Site (SRS) - 13448

Energy Technology Data Exchange (ETDEWEB)

Lawless, W.F. [Paine College, Departments of Math and Psychology, 1235 15th Street, Augusta, GA 30901 (United States)

2013-07-01

Citizen involvement in DOE's decision-making for the environmental cleanup from DOE's management of its nuclear wastes across the DOE complex has had a positive effect on the cleanup of its SRS site, characterized by an acceleration of cleanup not only for the Transuranic wastes at SRS, but also for DOE's first two closures of HLW tanks, both of which occurred at SRS. The Citizens around SRS had pushed successfully for the closures of Tanks 17 and 20 in 1997, becoming the first closures of HLW tanks under regulatory guidance in the USA. However, since then, HLW tank closures ceased due to a lawsuit, the application of new tank clean-up technology, interagency squabbling between DOE and NRC over tank closure criteria, and finally and almost fatally, from budget pressures. Despite an agreement with its regulators for the closure of Tanks 18 and 19 by the end of calendar year 2012, the outlook in Fall 2011 to close these two tanks had dimmed. It was at this point that the citizens around SRS became reengaged with tank closures, helping DOE to reach its agreed upon milestone. (authors)

Radionuclide field lysimeter experiment (RadFLEx): geochemical and hydrological data for SRS performance assessments

Energy Technology Data Exchange (ETDEWEB)

Kaplan, D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Powell, B. [Clemson Univ., SC (United States); Barber, K. [Clemson Univ., SC (United States); Devol, T. [Clemson Univ., SC (United States); Dixon, K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Erdmann, B. [Clemson Univ., SC (United States); Maloubier, M. [Clemson Univ., SC (United States); Martinez, N. [Clemson Univ., SC (United States); Montgomery, D. [Clemson Univ., SC (United States); Peruski, K. [Clemson Univ., SC (United States); Roberts, K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Witmer, M. [Clemson Univ., SC (United States)

2017-12-12

The SRNL Radiological Field Lysimeter Experiment (RadFLEx) is a one-of-a-kind test bed facility designed to study radionuclide geochemical processes in the Savannah River Site (SRS) vadose zone at a larger spatial scale (from grams to tens of kilograms of sediment) and temporal scale (from months to decade) than is readily afforded through laboratory studies. RadFLEx is a decade-long project that was initiated on July 5, 2012 and is funded by six different sources. The objective of this status report is as follows: 1) to report findings to date that have an impact on SRS performance assessment (PA) calculations, and 2) to provide performance metrics of the RadFLEx program. The PA results are focused on measurements of transport parameters, such as distribution coefficients (Kd values), solubility, and unsaturated flow values. As this is an interim report, additional information from subsequent research may influence our interpretation of current results. Research related to basic understanding of radionuclide geochemistry in these vadose zone soils and other source terms are not described here but are referenced for the interested reader.

Performance Modeling Applied to the Treatment and Disposal of a Mixed Waste at the SRS

International Nuclear Information System (INIS)

Pickett, J.B.; Jantzen, C.M.; Cook, J.R.; Whited, A.R.; Field, R.A.

1997-05-01

Performance modeling for Low Level Mixed Waste disposal was conducted using the measured leach rates from a number of vitrified waste formulations. The objective of the study was to determine if the improved durability of a vitrified mixed waste would allow trench disposal at the Savannah River Site (SRS). Leaching data were compiled from twenty-nine diverse reference glasses, encompassing a wide range of exposed glass surface area to leachant volume ratios (SA/V), and various leachant solutions; all of which had been leached at 90 degrees Celsius, using the MCC-1 or PCT procedures (ASTM Procedures C1220-92 and C1285-94, respectively). The normalized leach rates were scaled to the ambient disposal temperature of 25 degrees Celsius, and compared to the allowable leach rate of uranium - which would meet the performance assessment requirements. The results indicated that a glass of above average durability (vs. the reference glasses) would meet the uranium leaching concentration for direct SRS trench disposal

CEMENTITIOUS GROUT FOR CLOSING SRS HIGH LEVEL WASTE TANKS - #12315

Energy Technology Data Exchange (ETDEWEB)

Langton, C.; Burns, H.; Stefanko, D.

2012-01-10

In 1997, the first two United States Department of Energy (US DOE) high level waste tanks (Tanks 17-F and 20-F: Type IV, single shell tanks) were taken out of service (permanently closed) at the Savannah River Site (SRS). In 2012, the DOE plans to remove from service two additional Savannah River Site (SRS) Type IV high-level waste tanks, Tanks 18-F and 19-F. These tanks were constructed in the late 1950's and received low-heat waste and do not contain cooling coils. Operational closure of Tanks 18-F and 19-F is intended to be consistent with the applicable requirements of the Resource Conservation and Recovery Act (RCRA) and the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) and will be performed in accordance with South Carolina Department of Health and Environmental Control (SCDHEC). The closure will physically stabilize two 4.92E+04 cubic meter (1.3 E+06 gallon) carbon steel tanks and isolate and stabilize any residual contaminants left in the tanks. The closure will also fill, physically stabilize and isolate ancillary equipment abandoned in the tanks. A Performance Assessment (PA) has been developed to assess the long-term fate and transport of residual contamination in the environment resulting from the operational closure of the F-Area Tank Farm (FTF) waste tanks. Next generation flowable, zero-bleed cementitious grouts were designed, tested, and specified for closing Tanks 18-F and 19-F and for filling the abandoned equipment. Fill requirements were developed for both the tank and equipment grouts. All grout formulations were required to be alkaline with a pH of 12.4 and chemically reduction potential (Eh) of -200 to -400 to stabilize selected potential contaminants of concern. This was achieved by including Portland cement and Grade 100 slag in the mixes, respectively. Ingredients and proportions of cementitious reagents were selected and adjusted, respectively, to support the mass placement strategy developed by

Wind system documentation

Energy Technology Data Exchange (ETDEWEB)

Froggatt, J.R.; Tatum, C.P.

1993-01-15

Atmospheric transport and diffusion models have been developed by the Environmental Technology Section (ETS) of the Savannah River Technology Center to calculate the location and concentration of toxic or radioactive materials during an accidental release at the Savannah River Site (SRS). The output from these models has been used to support initial on-site and off-site emergency response activities such as protective action decision making and field monitoring coordination. These atmospheric transport and diffusion models have been incorporated into an automated computer-based system called the (Weather Information and Display) System and linked to real-time meteorological and radiological monitoring instruments to provide timely information for these emergency response activities (Hunter, 1990). This report documents various aspects of the WIND system.

Split-root systems applied to the study of the legume-rhizobial symbiosis: what have we learned?

Science.gov (United States)

Larrainzar, Estíbaliz; Gil-Quintana, Erena; Arrese-Igor, Cesar; González, Esther M; Marino, Daniel

2014-12-01

Split-root system (SRS) approaches allow the differential treatment of separate and independent root systems, while sharing a common aerial part. As such, SRS is a useful tool for the discrimination of systemic (shoot origin) versus local (root/nodule origin) regulation mechanisms. This type of approach is particularly useful when studying the complex regulatory mechanisms governing the symbiosis established between legumes and Rhizobium bacteria. The current work provides an overview of the main insights gained from the application of SRS approaches to understand how nodule number (nodulation autoregulation) and nitrogen fixation are controlled both under non-stressful conditions and in response to a variety of stresses. Nodule number appears to be mainly controlled at the systemic level through a signal which is produced by nodule/root tissue, translocated to the shoot, and transmitted back to the root system, involving shoot Leu-rich repeat receptor-like kinases. In contrast, both local and systemic mechanisms have been shown to operate for the regulation of nitrogenase activity in nodules. Under drought and heavy metal stress, the regulation is mostly local, whereas the application of exogenous nitrogen seems to exert a regulation of nitrogen fixation both at the local and systemic levels. © 2014 Institute of Botany, Chinese Academy of Sciences.

Responsiveness and Minimal Important Changes of the Scoliosis Research Society-22 Patient Questionnaire in Subjects With Mild Adolescent and Moderate Adult Idiopathic Scoliosis Undergoing Multidisciplinary Rehabilitation.

Science.gov (United States)

Monticone, Marco; Ambrosini, Emilia; Rocca, Barbara; Foti, Calogero; Ferrante, Simona

2017-06-01

Single-center, prospective study. Evaluating the responsiveness and minimal important changes (MICs) for the Scoliosis Research Society-22 Patient Questionnaire (SRS-22) in adolescent idiopathic scoliosis (AIS) and adult idiopathic scoliosis (AS). Despite the SRS-22 properties have been investigated in various different languages, there is still a lack of information concerning responsiveness and MIC, limiting the use of SRS-22 for clinical and research purposes. At the beginning and end of multidisciplinary rehabilitation programs, 149 subjects with mild AIS (Cobb angle self-perceived image, 0.40 (0.609;79;42) for AIS and 0.60 (0.751;61;82) for AS. Correlations between change scores of the SRS-22 domains and GPE were low to moderate, ranging from -0.347 to -0.667. The SRS-22 was sensitive in detecting clinical changes in subjects with adolescent and adult scoliosis. We recommend taking the MICs provided into account when assessing patients' improvement or planning studies in these clinical contexts. 3.

Sensitivity and variability of Presage dosimeter formulations in sheet form with application to SBRT and SRS QA

Energy Technology Data Exchange (ETDEWEB)

Dumas, Michael, E-mail: mdumas1127@gmail.com [Department of Radiation Oncology, Wayne State University School of Medicine and Karmanos Cancer Institute Detroit, Detroit, Michigan 48201 and Department of Radiation Oncology, Henry Ford Hospital, Detroit, Michigan 48202 (United States); Rakowski, Joseph T. [Department of Radiation Oncology, Wayne State University School of Medicine and Karmanos Cancer Institute Detroit, Detroit, Michigan 48201 (United States)

2015-12-15

Purpose: To measure sensitivity and stability of the Presage dosimeter in sheet form for various chemical concentrations over a range of clinical photon energies and examine its use for stereotactic body radiation therapy (SBRT) and stereotactic radiosurgery (SRS) QA. Methods: Presage polymer dosimeters were formulated to investigate and optimize their sensitivity and stability. The dosimeter is composed of clear polyurethane base, leucomalachite green (LMG) reporting dye, and bromoform radical initiator in 0.9–1.0 mm thick sheets. The chemicals are mixed together for 2 min, cast in an aluminum mold, and left to cure at 60 psi for a minimum of two days. Dosimeter response was characterized at energies Co-60, 6 MV, 10 MV flattening-filter free, 15 MV, 50 kVp (mean 19.2 keV), and Ir-192. The dosimeters were scanned by a Microtek Scanmaker i800 at 300 dpi, 2{sup 16} bit depth per color channel. Red component images were analyzed with ImageJ and RIT. SBRT QA was done with gamma analysis tolerances of 2% and 2 mm DTA. Results: The sensitivity of the Presage dosimeter increased with increasing concentration of bromoform. Addition of tin catalyst decreased curing time and had negligible effect on sensitivity. LMG concentration should be at least as high as the bromoform, with ideal concentration being 2% wt. Gamma Knife SRS QA measurements of relative output and profile widths were within 2% of manufacturer’s values validated at commissioning, except the 4 mm collimator relative output which was within 3%. The gamma pass rate of Presage with SBRT was 73.7%, compared to 93.1% for EBT2 Gafchromic film. Conclusions: The Presage dosimeter in sheet form was capable of detecting radiation over all tested photon energies and chemical concentrations. The best sensitivity and photostability of the dosimeter were achieved with 2.5% wt. LMG and 8.2% wt. bromoform. Scanner used should not emit any UV radiation as it will expose the dosimeter, as with the Epson 10000 XL scanner

Resolving the Gordian Knot: Srs2 Strips Intermediates Formed during Homologous Recombination.

Science.gov (United States)

Ghodke, Harshad; Lewis, Jacob S; van Oijen, Antoine M

2018-03-01

Cells use a suite of specialized enzymes to repair chromosomal double-strand breaks (DSBs). Two recent studies describe how single-molecule fluorescence imaging techniques are used in the direct visualization of some of the key molecular steps involved. De Tullio et al. and Kaniecki et al. watch individual Srs2 helicase molecules disrupt repair intermediates formed by RPA, Rad51, and Rad52 on DNA during homologous recombination. Copyright © 2017 Elsevier Ltd. All rights reserved.

The Daresbury personnel safety system

International Nuclear Information System (INIS)

Poole, D.E.; Ring, T.

1989-01-01

The personnel safety system designed for the SRS at Daresbury is a unified system covering the three accelerators of the source itself, the beamlines and the experimental stations. The system has also been applied to the experimental areas of the Nuclear Structure Facility, and is therefore established as a site standard. A dual guardline interlock module forms a building block for a relay based interlock system completely independent of the machine control system, although comprehensive monitoring of the system status via the control system computer is a feature. An outline of the design criteria adopted for the system is presented together with a more detailed description of the philosophy of the guardline logic and the way this is implemented in a standard modular form. The emphasis is on the design features of a modern microprocessor based variant of the original SRS system. Experience with the original system during build-up and operation of the SRS facility is described. 2 refs., 4 figs

Clemson final report: High temperature formulations for SRS soils

International Nuclear Information System (INIS)

Schumacher, R.F.

1997-01-01

This study was undertaken to demonstrate the application of a DC arc melter to in-situ vitrification of SRS soils. The melter that was available at the DOE/Industrial Vitrification Laboratory at Clemson University was equipped with opposing solid electrodes. To simulate field conditions, two hollow electrode configurations were evaluated which allowed fluxes to be injected into the melter while the soils were being vitrified. the first 4 runs utilized pre-blended flux (two runs) and attempted flux injection (two runs). These runs were terminated prematurely due to offgas sampling problems and melt freezing. The remaining four runs utilized a different electrode geometry, and the runs were not interrupted to change out the offgas sampling apparatus. These runs were conducted successfully

Response of the polar cap boundary and the current system to changes in IMF observed from the MAGSAT satellite in the southern hemisphere during summer

International Nuclear Information System (INIS)

Bhatnagar, V.P.; Burrows, J.R.

1987-01-01

The magnetic field vector residuals observed from the Magsat satellite have been used to obtain the dependence of the polar cap boundary and the current system on IMF for quiet and mildly disturbed conditions. The study has been carried out for the summer months in the Southern Hemisphere. ''Shear reversals'' (SRs) in vector residuals indicative of the infinite current sheet approximation of the field-aligned currents (FACs) indicate roughly the polar cap boundary or the poleward boundary of the plasma sheet. This is also the poleward edge of the region 1 FACs. The SR is defined to occur at the latitude where the vector goes to minimum and changes direction by approximately 180 0 . It is found that SRs mainly occur when the interplanetary magnetic field (IMF) has a southward-directed Bsub(z) component and in the latitude range of about 70 0 -80 0 . SRs in the dusk sector occur predominantly when the azimuthal component Bsub(y) is positive and in the dawn sector when Bsub(y) is negative, irrespective of the sign of Bsub(z). These results agree with the known merging process of IMF with magnetopause field lines. When SRs occur on both dawn and dusk sectors, the residuals over the entire polar cap are nearly uniform in direction and magnitude, indicating negligible polar currents. Similar behaviour is observed during highly disturbed conditions usually associated with large negative values of Bsub(z). Forty-one Magsat orbits with such SRs are quantitatively modelled for preliminary case studies of the resulting current distribution. It is found that SRs, in the plane perpendicular to the geomagnetic field, for the current vectors and the magnetic vector residuals (perturbations relative to the unperturbed field) occur at almost the same latitudes. The electrojet intensities range from 1.2 x 10 4 to 6.5 x 10 5 A (amperes). A preliminary classification of polar cap boundary crossings characterized by vector rotations rather than SRs also shows that they tend to

Performance Evaluation of Speech Recognition Systems as a Next-Generation Pilot-Vehicle Interface Technology

Science.gov (United States)

Arthur, Jarvis J., III; Shelton, Kevin J.; Prinzel, Lawrence J., III; Bailey, Randall E.

2016-01-01

During the flight trials known as Gulfstream-V Synthetic Vision Systems Integrated Technology Evaluation (GV-SITE), a Speech Recognition System (SRS) was used by the evaluation pilots. The SRS system was intended to be an intuitive interface for display control (rather than knobs, buttons, etc.). This paper describes the performance of the current "state of the art" Speech Recognition System (SRS). The commercially available technology was evaluated as an application for possible inclusion in commercial aircraft flight decks as a crew-to-vehicle interface. Specifically, the technology is to be used as an interface from aircrew to the onboard displays, controls, and flight management tasks. A flight test of a SRS as well as a laboratory test was conducted.

Development of the Italian version of the revised Scoliosis Research Society-22 Patient Questionnaire, SRS-22r-I: cross-cultural adaptation, factor analysis, reliability, and validity.

Science.gov (United States)

Monticone, Marco; Baiardi, Paola; Calabrò, David; Calabrò, Fabio; Foti, Calogero

2010-11-15

Evaluation of the psychometric properties of a translated and culturally adapted questionnaire. Translating, culturally adapting, and validating the Italian version of the revised Scoliosis Research Society-22 Patient Questionnaire (SRS-22r-I) in order to allow its use with Italian-speaking patients with adolescent idiopathic scoliosis (AIS). Increasing attention is being given to health-related quality of life measures as a means of adding information about the evaluation of AIS. A translated form of the revised SRS-22 has never been validated in Italian patients with AIS. The development of the SRS-22 questionnaire involved its translation and back-translation, a final review by an Expert Committee, and testing of the prefinal version to establish its correspondence to the original English version. Psychometric testing included factor analysis, reliability by internal consistency (Cronbach alpha) and test-retest repeatability (Intraclass Coefficient Correlation), and concurrent validity (Pearson correlation) by comparing the SRS-22r-I domains with the Short-Form Health Survey (SF-36) subscales. It took 4 months to develop a shared version of the SRS-22r-I, which proved to be satisfactorily acceptable when administered to 223 subjects with AIS. Factor analysis indicated a 4-factor solution (54% of the explained variance), and the questionnaire had an acceptable level of internal consistency (α = 0.77) and a high level of test-retest reliability (intraclass correlation coefficient = 0.957). In terms of concurrent validity, the correlations with the related Short-Form-36 subscales were moderate to good in the case of the Pain and Mental Health domains, and moderate in the case of the Function and Self-Image domains. The Italian translation of the SRS-22r has a good factorial structure and psychometric properties, and replicates the results of existing English versions of the questionnaire. Its use for research purposes can therefore be recommended.

Commercial Submersible Mixing Pump For SRS Tank Waste Removal - 15223

Energy Technology Data Exchange (ETDEWEB)

Hubbard, Mike [Savannah River Remediation, LLC., Aiken, SC (United States); Herbert, James E. [Savannah River Remediation, LLC., Aiken, SC (United States); Scheele, Patrick W. [Savannah River Remediation, LLC., Aiken, SC (United States)

2015-01-12

The Savannah River Site Tank Farms have 45 active underground waste tanks used to store and process nuclear waste materials. There are 4 different tank types, ranging in capacity from 2839 m³ to 4921 m³ (750,000 to 1,300,000 gallons). Eighteen of the tanks are older style and do not meet all current federal standards for secondary containment. The older style tanks are the initial focus of waste removal efforts for tank closure and are referred to as closure tanks. Of the original 51 underground waste tanks, six of the original 24 older style tanks have completed waste removal and are filled with grout. The insoluble waste fraction that resides within most waste tanks at SRS requires vigorous agitation to suspend the solids within the waste liquid in order to transfer this material for eventual processing into glass filled canisters at the Defense Waste Processing Facility (DWPF). SRS suspends the solid waste by use of recirculating mixing pumps. Older style tanks generally have limited riser openings which will not support larger mixing pumps, since the riser access is typically 58.4 cm (23 inches) in diameter. Agitation for these tanks has been provided by four long shafted standard slurry pumps (SLP) powered by an above tank 112KW (150 HP) electric motor. The pump shaft is lubricated and cooled in a pressurized water column that is sealed from the surrounding waste in the tank. Closure of four waste tanks has been accomplished utilizing long shafted pump technology combined with heel removal using multiple technologies. Newer style waste tanks at SRS have larger riser openings, allowing the processing of waste solids to be accomplished with four large diameter SLPs equipped with 224KW (300 HP) motors. These tanks are used to process the waste from closure tanks for DWPF. In addition to the SLPs, a 224KW (300 HP) submersible mixer pump (SMP) has also been developed and deployed within older style tanks. The SMPs are product cooled and

Mixing Modeling Analysis For SRS Salt Waste Disposition

International Nuclear Information System (INIS)

Lee, S.

2011-01-01

Nuclear waste at Savannah River Site (SRS) waste tanks consists of three different types of waste forms. They are the lighter salt solutions referred to as supernate, the precipitated salts as salt cake, and heavier fine solids as sludge. The sludge is settled on the tank floor. About half of the residual waste radioactivity is contained in the sludge, which is only about 8 percentage of the total waste volume. Mixing study to be evaluated here for the Salt Disposition Integration (SDI) project focuses on supernate preparations in waste tanks prior to transfer to the Salt Waste Processing Facility (SWPF) feed tank. The methods to mix and blend the contents of the SRS blend tanks were evalutaed to ensure that the contents are properly blended before they are transferred from the blend tank such as Tank 50H to the SWPF feed tank. The work consists of two principal objectives to investigate two different pumps. One objective is to identify a suitable pumping arrangement that will adequately blend/mix two miscible liquids to obtain a uniform composition in the tank with a minimum level of sludge solid particulate in suspension. The other is to estimate the elevation in the tank at which the transfer pump inlet should be located where the solid concentration of the entrained fluid remains below the acceptance criterion (0.09 wt% or 1200 mg/liter) during transfer operation to the SWPF. Tank 50H is a Waste Tank that will be used to prepare batches of salt feed for SWPF. The salt feed must be a homogeneous solution satisfying the acceptance criterion of the solids entrainment during transfer operation. The work described here consists of two modeling areas. They are the mixing modeling analysis during miscible liquid blending operation, and the flow pattern analysis during transfer operation of the blended liquid. The modeling results will provide quantitative design and operation information during the mixing/blending process and the transfer operation of the blended

Shock Protection of Portable Electronic Products: Shock Response Spectrum, Damage Boundary Approach, and Beyond

Directory of Open Access Journals (Sweden)

Suresh Goyal

1997-01-01

Full Text Available The pervasive shock response spectrum (SRS and damage boundary methods for evaluating product fragility and designing external cushioning for shock protection are described in detail with references to the best available literature. Underlying assumptions are carefully reviewed and the central message of the SRS is highlighted, particularly as it relates to standardized drop testing. Shortcomings of these methods are discussed, and the results are extended to apply to more general systems. Finally some general packaging and shock-mounting strategies are discussed in the context of protecting a fragile disk drive in a notebook computer, although the conclusions apply to other products as well. For example, exterior only cushioning (with low restitution to reduce subsequent impacts will provide a slenderer form factor than the next best strategy: interior cushioning with a “dead” hard outer shell.

SU-F-T-626: Intracranial SRS Re-Treatment Without Acquisition of New CT Images

International Nuclear Information System (INIS)

Wiant, D; Manning, M; Liu, H; Maurer, J; Hayes, T; Sintay, B

2016-01-01

Purpose: Linear accelerator based stereotactic radiosurgery (SRS) for multiple intracranial lesions with frequent surveillance is becoming a popular treatment option. This strategy leads to retreatment with SRS as new lesions arise. Currently, each course of treatment uses magnetic resonance (MR) and computed tomography (CT) images for treatment planning. We propose that new MR images, with course 1 CT images, may be used for future treatment plans with negligible loss of dosimetric accuracy. Methods: Ten patients that received multiple courses of SRS were retrospectively reviewed. The treatment plans and contours from non-initial courses were copied to the initial CTs and recalculated. Doses metrics for the plans calculated on the initial CTs and later CTs were compared. All CT scans were acquired on a Philips CT scanner with a 600 mm field of view and 1 mm slice thickness (Philips Healthcare, Andover, MA). All targets were planned to 20 Gy and calculated in Eclipse V. 13.6 (Varian, Palo Alto, CA) using analytic anisotropic algorithm with 1 mm calculation grid. Results: Sixteen lesions were evaluated. The mean time between courses was 250 +/− 215 days (range 103–979). The mean target volume was 2.0 +/− 2.9 cc (range 0.1–10.1). The average difference in mean target dose between the two calculations was 0.2 +/− 0.3 Gy (range 0.0 – 1.0). The mean conformity index (CI) was 1.28 +/− 0.14 (range 1.07 – 1.82). The average difference in CI was 0.03 +/− 0.16 (range 0.00 – 0.44). Targets volumes < 0.5 cc showed the largest changes in both metrics. Conclusion: Continued treatment based on initial CT images is feasible. Dose calculation on the initial CT for future treatments provides reasonable dosimetric accuracy. Changes in dose metrics are largest for small volumes, and are likely dominated by partial volume effects in target definition.

Summary report for 1990 inservice inspection (ISI) of SRS 100-K reactor tank

International Nuclear Information System (INIS)

Morrison, J.M.; Loibl, M.W.

1990-01-01

The integrity of the SRS reactor tanks is a key factor affecting their suitability for continued service since, unlike the external piping system and components, the tanks are virtually irreplaceable. Cracking in various areas of the process water piping systems has occurred beginning in about 1960 as a result of several degradation mechanisms, chiefly intergranular stress corrosion cracking (IGSCC) and chloride-induced transgranular cracking. The purpose of this inspection was to determine if selected welds in the K Reactor tank wall contained any indications of IGSCC. These portions included areas in and beyond the weld HAZ, extending out as far as two to three inches from the centerline of the welds, plus selected areas of base metal at the intersection of the main tank vertical and mid-girth welds. No evidence of such degradation was found in any of the areas examined. This inspection comprised approximately 60% of the accessible weld length in the K Reactor tank. Initial setup of the tank, which prior to inspection contained Mark 60B target assemblies but no Mark 22 fuel assemblies, began on January 14, 1990. The inspection was completed on March 9, 1990

Experimental Determination and Thermodynamic Modeling of Electrical Conductivity of SRS Waste Tank Supernate

Energy Technology Data Exchange (ETDEWEB)

Pike, J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Reboul, S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2015-06-01

SRS High Level Waste Tank Farm personnel rely on conductivity probes for detection of incipient overflow conditions in waste tanks. Minimal information is available concerning the sensitivity that must be achieved such that that liquid detection is assured. Overly sensitive electronics results in numerous nuisance alarms for these safety-related instruments. In order to determine the minimum sensitivity required of the probe, Tank Farm Engineering personnel need adequate conductivity data to improve the existing designs. Little or no measurements of liquid waste conductivity exist; however, the liquid phase of the waste consists of inorganic electrolytes for which the conductivity may be calculated. Savannah River Remediation (SRR) Tank Farm Facility Engineering requested SRNL to determine the conductivity of the supernate resident in SRS waste Tank 40 experimentally as well as computationally. In addition, SRNL was requested to develop a correlation, if possible, that would be generally applicable to liquid waste resident in SRS waste tanks. A waste sample from Tank 40 was analyzed for composition and electrical conductivity as shown in Table 4-6, Table 4-7, and Table 4-9. The conductivity for undiluted Tank 40 sample was 0.087 S/cm. The accuracy of OLI Analyzer™ was determined using available literature data. Overall, 95% of computed estimates of electrical conductivity are within ±15% of literature values for component concentrations from 0 to 15 M and temperatures from 0 to 125 °C. Though the computational results are generally in good agreement with the measured data, a small portion of literature data deviates as much as ±76%. A simplified model was created that can be used readily to estimate electrical conductivity of waste solution in computer spreadsheets. The variability of this simplified approach deviates up to 140% from measured values. Generally, this model can be applied to estimate the conductivity within a factor of two. The comparison of the

Mesoscale atmospheric modeling of accidental toxic and radioactive releases for emergency response at SRS

International Nuclear Information System (INIS)

O'Steen, B.L.; Fast, J.D.

1992-01-01

In August of 1991, the Environmental Transport Group (ETG) began the development of an advanced Emergency Response (ER) system based upon the Colorado State University Regional Atmospheric Modeling System 1 (RAMS). This model simulates the three-dimensional, time-dependent, flow field and thermodynamic structure of the planetary boundary layer (PBL). A companion Lagrangian Particle Dispersion Model 2 (LPDM) simulates contaminant transport based on the flow and turbulence fields generated by RAMS. The current report describes progress to date on this project in the areas of data development, data assimilation, and operational (real-time) procedures. In particular, a diagnostic capability for simulating contaminant transport is demonstrated

Heteroduplex DNA position defines the roles of the Sgs1, Srs2, and Mph1 helicases in promoting distinct recombination outcomes.

Directory of Open Access Journals (Sweden)

Katrina Mitchel

Full Text Available The contributions of the Sgs1, Mph1, and Srs2 DNA helicases during mitotic double-strand break (DSB repair in yeast were investigated using a gap-repair assay. A diverged chromosomal substrate was used as a repair template for the gapped plasmid, allowing mismatch-containing heteroduplex DNA (hDNA formed during recombination to be monitored. Overall DSB repair efficiencies and the proportions of crossovers (COs versus noncrossovers (NCOs were determined in wild-type and helicase-defective strains, allowing the efficiency of CO and NCO production in each background to be calculated. In addition, the products of individual NCO events were sequenced to determine the location of hDNA. Because hDNA position is expected to differ depending on whether a NCO is produced by synthesis-dependent-strand-annealing (SDSA or through a Holliday junction (HJ-containing intermediate, its position allows the underlying molecular mechanism to be inferred. Results demonstrate that each helicase reduces the proportion of CO recombinants, but that each does so in a fundamentally different way. Mph1 does not affect the overall efficiency of gap repair, and its loss alters the CO-NCO by promoting SDSA at the expense of HJ-containing intermediates. By contrast, Sgs1 and Srs2 are each required for efficient gap repair, strongly promoting NCO formation and having little effect on CO efficiency. hDNA analyses suggest that all three helicases promote SDSA, and that Sgs1 and Srs2 additionally dismantle HJ-containing intermediates. The hDNA data are consistent with the proposed role of Sgs1 in the dissolution of double HJs, and we propose that Srs2 dismantles nicked HJs.

Factors influencing intentions to use social recommender systems: a social exchange perspective.

Science.gov (United States)

Chang, Tsung-Sheng; Hsiao, Wei-Hung

2013-05-01

This study employs the perspective of social exchange theory and seeks to understand users' intentions to use social recommender systems (SRS) through three psychological factors: trust, shared values, and reputation. We use structural equation modeling to analyze 221 valid questionnaires. The results show that trust has a direct positive influence on the intention to use SRS, followed by shared values, whereas reputation has an indirect influence on SRS use. We further discuss specific recommendations concerning these factors for developing SRS.

Phase II Nuclide Partition Laboratory Study Influence of Cellulose Degradation Products on the Transport of Nuclides from SRS Shallow Land Burial Facilities; FINAL

International Nuclear Information System (INIS)

Serkiz, S.M.

1999-01-01

Degradation products of cellulosic materials (e.g., paper and wood products) can significantly influence the subsurface transport of metals and radionuclides. Codisposal of radionuclides with cellulosic materials in the E-Area slit trenches at the Savannah River Site (SRS) is, therefore, expected to influence nuclide fate and transport in the subsurface. Due to the complexities of these systems and the scarcity of site-specific data, the effects of cellulose waste loading and its subsequent influence on nuclide transport are not well established

High-Level software requirements specification for the TWRS controlled baseline database system

International Nuclear Information System (INIS)

Spencer, S.G.

1998-01-01

This Software Requirements Specification (SRS) is an as-built document that presents the Tank Waste Remediation System (TWRS) Controlled Baseline Database (TCBD) in its current state. It was originally known as the Performance Measurement Control System (PMCS). Conversion to the new system name has not occurred within the current production system. Therefore, for simplicity, all references to TCBD are equivalent to PMCS references. This SRS will reference the PMCS designator from this point forward to capture the as-built SRS. This SRS is written at a high-level and is intended to provide the design basis for the PMCS. The PMCS was first released as the electronic data repository for cost, schedule, and technical administrative baseline information for the TAAS Program. During its initial development, the PMCS was accepted by the customer, TARS Business Management, with no formal documentation to capture the initial requirements

Savannah River Site (SRS) implementation program plan for DNFSB Recommendation 90-2

International Nuclear Information System (INIS)

Talukdar, B.K.; Loceff, F.

1993-01-01

The Defense Nuclear Facilities Safety Board (DNFSB) based on its review and evaluation of the content and implementation of standards relating to design, construction, operation, and decommissioning of Defense Nuclear Facilities has made the recommendations (90-2) which when implemented would assure comparable or equivalent levels of safety to the environment, public and workers as required for the commercial nuclear facilities. DOE has accepted the DNFSB 90-2 recommendations and have directed SRS and other M ampersand Os to implement them. This report discusses implementation program which commits to developing Requirement Identification Documents (RID's) for all defense nuclear facilities in the DOE complex

Use Of Cementitious Materials For SRS Reactor Facility In-Situ Decommissioning - 11620

International Nuclear Information System (INIS)

Langton, C.; Stefanko, D.; Serrato, M.; Blankenship, J.; Griffin, W.; Waymer, J.; Matheny, D.; Singh, D.

2010-01-01

The United States Department of Energy (US DOE) concept for facility in-situ decommissioning (ISD) is to physically stabilize and isolate in tact, structurally sound facilities that are no longer needed for their original purpose of, i.e., producing (reactor facilities), processing (isotope separation facilities) or storing radioactive materials. The Savannah River Site 105-P and 105-R Reactor Facility ISD requires about 250,000 cubic yards of grout to fill the below grade structure. The fills are designed to prevent subsidence, reduce water infiltration, and isolate contaminated materials. This work is being performed as a Comprehensive Environmental Response, Compensations and Liability Act (CERCLA) action and is part of the overall soil and groundwater completion projects for P- and R-Areas. Cementitious materials were designed for the following applications: (1) Below grade massive voids/rooms: Portland cement-based structural flowable fills for - Bulk filling, Restricted placement and Underwater placement. (2) Special below grade applications for reduced load bearing capacity needs: Cellular portland cement lightweight fill (3) Reactor vessel fills that are compatible with reactive metal (aluminum metal) components in the reactor vessels: Calcium sulfoaluminate flowable fill, and Magnesium potassium phosphate flowable fill. (4) Caps to prevent water infiltration and intrusion into areas with the highest levels of radionuclides: Portland cement based shrinkage compensating concrete. A system engineering approach was used to identify functions and requirements of the fill and capping materials. Laboratory testing was performed to identify candidate formulations and develop final design mixes. Scale-up testing was performed to verify material production and placement as well as fresh and cured properties. The 105-P and 105-R ISD projects are currently in progress and are expected to be complete in 2012. The focus of this paper is to describe the (1) grout mixes

USE OF CEMENTITIOUS MATERIALS FOR SRS REACTOR FACILITY IN-SITU DECOMMISSIONING - 11620

Energy Technology Data Exchange (ETDEWEB)

Langton, C.; Stefanko, D.; Serrato, M.; Blankenship, J.; Griffin, W.; Waymer, J.; Matheny, D.; Singh, D.

2010-12-07

The United States Department of Energy (US DOE) concept for facility in-situ decommissioning (ISD) is to physically stabilize and isolate in tact, structurally sound facilities that are no longer needed for their original purpose of, i.e., producing (reactor facilities), processing (isotope separation facilities) or storing radioactive materials. The Savannah River Site 105-P and 105-R Reactor Facility ISD requires about 250,000 cubic yards of grout to fill the below grade structure. The fills are designed to prevent subsidence, reduce water infiltration, and isolate contaminated materials. This work is being performed as a Comprehensive Environmental Response, Compensations and Liability Act (CERCLA) action and is part of the overall soil and groundwater completion projects for P- and R-Areas. Cementitious materials were designed for the following applications: (1) Below grade massive voids/rooms: Portland cement-based structural flowable fills for - Bulk filling, Restricted placement and Underwater placement. (2) Special below grade applications for reduced load bearing capacity needs: Cellular portland cement lightweight fill (3) Reactor vessel fills that are compatible with reactive metal (aluminum metal) components in the reactor vessels: Calcium sulfoaluminate flowable fill, and Magnesium potassium phosphate flowable fill. (4) Caps to prevent water infiltration and intrusion into areas with the highest levels of radionuclides: Portland cement based shrinkage compensating concrete. A system engineering approach was used to identify functions and requirements of the fill and capping materials. Laboratory testing was performed to identify candidate formulations and develop final design mixes. Scale-up testing was performed to verify material production and placement as well as fresh and cured properties. The 105-P and 105-R ISD projects are currently in progress and are expected to be complete in 2012. The focus of this paper is to describe the (1) grout mixes

SU-F-T-575: Verification of a Monte-Carlo Small Field SRS/SBRT Dose Calculation System

International Nuclear Information System (INIS)

Sudhyadhom, A; McGuinness, C; Descovich, M

2016-01-01

Purpose: To develop a methodology for validation of a Monte-Carlo dose calculation model for robotic small field SRS/SBRT deliveries. Methods: In a robotic treatment planning system, a Monte-Carlo model was iteratively optimized to match with beam data. A two-part analysis was developed to verify this model. 1) The Monte-Carlo model was validated in a simulated water phantom versus a Ray-Tracing calculation on a single beam collimator-by-collimator calculation. 2) The Monte-Carlo model was validated to be accurate in the most challenging situation, lung, by acquiring in-phantom measurements. A plan was created and delivered in a CIRS lung phantom with film insert. Separately, plans were delivered in an in-house created lung phantom with a PinPoint chamber insert within a lung simulating material. For medium to large collimator sizes, a single beam was delivered to the phantom. For small size collimators (10, 12.5, and 15mm), a robotically delivered plan was created to generate a uniform dose field of irradiation over a 2×2cm 2 area. Results: Dose differences in simulated water between Ray-Tracing and Monte-Carlo were all within 1% at dmax and deeper. Maximum dose differences occurred prior to dmax but were all within 3%. Film measurements in a lung phantom show high correspondence of over 95% gamma at the 2%/2mm level for Monte-Carlo. Ion chamber measurements for collimator sizes of 12.5mm and above were within 3% of Monte-Carlo calculated values. Uniform irradiation involving the 10mm collimator resulted in a dose difference of ∼8% for both Monte-Carlo and Ray-Tracing indicating that there may be limitations with the dose calculation. Conclusion: We have developed a methodology to validate a Monte-Carlo model by verifying that it matches in water and, separately, that it corresponds well in lung simulating materials. The Monte-Carlo model and algorithm tested may have more limited accuracy for 10mm fields and smaller.

SU-F-T-578: Characterization of Vidar DosimetryPro Advantage RED Scanner with Application to SBRT and SRS QA

Energy Technology Data Exchange (ETDEWEB)

Dumas, M; Wen, N [Henry Ford Health System, Detroit, MI (United States)

2016-06-15

Purpose: To use Gafchromic EBT3 film to quantify key dosimetric characteristics of the Vidar DosimetryPro Advantage RED film scanner for use in SBRT/SRS QA, by analyzing scanner uniformity and dose sensitivity. Method: Gafchromic EBT3 film was used in this study. Films were irradiated using 6MV FFF and 10MV FFF beams from a Varian Edge linear accelerator, with setup of 100cm SAD at depth 5 cm. Nine doses were delivered per film, with calibration dose ranges of 1–10 Gy and 3–24 Gy for 6MV FFF, and 3–27 Gy for 10MV FFF. Films were scanned with the long side of the film parallel to the detector array. Dose calibration curves were fitted to a 3rd degree polynomial. The derivative of a calibration curve was taken to determine the scanner’s sensitivity per dose delivered (OD/Gy). Scanner non-uniformity was calculated in 2 dimensions by taking the mean of standard deviation in each row and column. Absolute dose SRS/SBRT Gamma analyses were performed with passing criteria of 3% and 1mm DTA. For comparison, Gamma analyses were also performed using an Epson Expression 10000 XL. Results: Uniformity for the Vidar scanner was 0.37% +/− 0.03% in the perpendicular to scan direction and 0.67% +/− 0.05% in the parallel to scan direction, with an overall uniformity of 0.52% +/− 0.03%. Epson red channel uniformity was 0.85% +/− 0.05% and 0.88% +/− 0.08% for the green channel. The Vidar average dose sensitivity from 1–10 Gy was 0.112 OD/Gy and 0.061 OD/Gy for 3–24 Gy. SBRT/SRS Gamma pass rates were 97.8 +/− 1.4 for Vidar and 97.5 +/− 1.4 for Epson. Conclusion: The Vidar scanner has 41% less non-uniformity compared to Epson XL10000 green channel. The dose sensitivity is 2–3 time greater for the Vidar scanner compared to the Epson in the SRS/SBRT dose range of 5–24 Gy.

Postoperative perceived health status in adolescent following idiopathic scoliosis surgical treatment: results using the adapted French version of Scoliosis Research Society Outcomes questionnaire (SRS-22).

Science.gov (United States)

Chaib, Y; Bachy, M; Zakine, S; Mary, P; Khouri, N; Vialle, R

2013-06-01

Assessing functional outcome from patient-based outcomes questionnaires are essential to the evaluation of adolescent idiopathic scoliosis surgical treatment At the minimum follow-up of 2 years, 45 operated on adolescent idiopathic scoliosis patients were mailed the French version of the Scoliosis Research Society Outcome Instrument (SRS-22) questionnaires containing items on pain, activities of daily living, and satisfaction. Mean values of the SRS-22 domains were 3,66 for the Pain domain, 3,85 for the Self-perceived image domain, 4,32 for the Function domain, 3,52 for the Mental health domain and 4,12 for the Global satisfaction with management domain. Mean value of the global SRS-22 score was 3,88. We showed no differences in functional SRS-22 health status in patients according to the type of curve (Lenke classification). We showed statistically significant correlations between the gain of Cobb angle and Patients self-image and function domain scores. There was a statistically significant correlation between preoperative Cobb angle and patient satisfaction with management. Even if Function and Self-image scores in our patients are close to control group values, indicating good short to mid-term outcome of surgical treatment, scores for pain and mental health status were significantly lower in patients than controls. Long-term follow-up studies conducted by multiple surgeons over successive generations are mandatory to assess clinical significance of these differences. Level IV. Retrospective study. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

Cortisol Predicts Behavioral Dysregulation and Length of Stay among Children Admitted for Psychiatric Inpatient Treatment

Science.gov (United States)

Luebbe, Aaron M.; Elledge, L. Christian; Kiel, Elizabeth J.; Stoppelbein, Laura

2012-01-01

Individual differences in behavioral regulation system (BRS) and stress response system (SRS) functioning may reflect greater biological sensitivity to context. The current study tested whether children's cortisol, a measure of the SRS, was related to observed dysregulated behavior, an indicator of the BRS, in a sample of children admitted for…

The SRS2 suppressor of rad6 mutations of Saccharomyces cerevisiae acts by channeling DNA lesions into the RAD52 DNA repair pathway

International Nuclear Information System (INIS)

Schiestl, R.H.; Prakash, S.; Prakash, L.

1990-01-01

rad6 mutants of Saccharomyces cerevisiae are defective in the repair of damaged DNA, DNA damage induced mutagenesis, and sporulation. In order to identify genes that can substitute for RAD6 function, the authors have isolated genomic suppressors of the UV sensitivity of rad6 deletion (rad6Δ) mutations and show that they also suppress the γ-ray sensitivity but not the UV mutagenesis or sporulation defects of rad6. The suppressors show semidominance for suppression of UV sensitivity and dominance for suppression of γ-ray sensitivity. The six suppressor mutations they isolated are all alleles of the same locus and are also allelic to a previously described suppressor of the rad6-1 nonsense mutation, SRS2. They show that suppression of rad6Δ is dependent on the RAD52 recombinational repair pathway since suppression is not observed in the rad6Δ SRS2 strain containing an additional mutation in either the RAD51, RAD52, RAD54, RAD55 or RAD57 genes. Possible mechanisms by which SRS2 may channel unrepaired DNA lesions into the RAD52 DNA repair pathway are discussed

Estimating Derived Response Levels at the Savannah River Site for Use with Emergency Response Models

International Nuclear Information System (INIS)

Simpkins, A.A.

2002-01-01

Emergency response computer models at the Savannah River Site (SRS) are coupled with real-time meteorological data to estimate dose to individuals downwind of accidental radioactive releases. Currently, these models estimate doses for inhalation and shine pathways, but do not consider dose due to ingestion of contaminated food products. The Food and Drug Administration (FDA) has developed derived intervention levels (DIL) which refer to the radionuclide-specific concentration in food present throughout the relevant period of time, with no intervention, that could lead to an individual receiving a radiation dose equal to the protective action guide. In the event of an emergency, concentrations in various food types are compared with these levels to make interdictions decisions. Prior to monitoring results being available, concentrations in the environmental media (i.e. soil), called derived response levels (DRLs), can be estimated from the DILs and directly compared with computer output to provide preliminary guidance as to whether intervention is necessary. Site-specific derived response levels (DRLs) are developed for ingestion pathways pertinent to SRS: milk, meat, fish, grain, produce, and beverage. This provides decision-makers with an additional tool for use immediately following an accident prior to the acquisition of food monitoring data

SU-F-T-587: Quality Assurance of Stereotactic Radiosurgery (SRS) and Stereotactic Body Radiation Therapy (SBRT) for Patient Specific Plans: A Comparison Between MATRIXX and Delta4 QA Devices

Energy Technology Data Exchange (ETDEWEB)

Tsai, YC; Lu, SH; Chen, LH; Kuo, SH; Wang, CW [National Taiwan University Hospital, Taipei City, Taiwan (China)

2016-06-15

Purpose: Patient-specific quality assurance (QA) is necessary to accurately deliver high dose radiation to the target, especially for stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT). Unlike previous 2 dimensional (D) array QA devices, Delta{sup 4} can verify the dose delivery in 3D. In this study, the difference between calculated and measured dose distribution was compared with two QA devices (MATRIXX and Delta{sup 4}) to evaluate the delivery accuracy. Methods: Twenty-seven SRS/SBRT plans with VMAT were verified with point-dose and dose-map analysis. We use an ion chamber (A1SL, 0.053cc) for point-dose measurement. For verification of the dose map, the differences between the calculated and measured doses were analyzed with a gamma index using MATRIXX and Delta{sup 4} devices. The passing criteria for gamma evaluation were set at 3 mm for distance-to-agreement (DTA) and 3% for dose-difference. A gamma index less than 1 was defined as the verification passing the criteria and satisfying at least 95% of the points. Results: The mean prescribed dose and fraction was 40 ± 14.41 Gy (range: 16–60) and 10 ± 2.35 fractions (range: 1–8), respectively. In point dose analysis, the differences between the calculated and measured doses were all less than 5% (mean: 2.12 ± 1.13%; range: −0.55% to 4.45%). In dose-map analysis, the average passing rates were 99.38 ± 0.96% (range: 95.31–100%) and 100 ± 0.12% (range: 99.5%–100%) for MATRIXX and Delta{sup 4}, respectively. Even using criteria of 2%/2 mm, the passing rate of Delta{sup 4} was still more than 95% (mean: 99 ± 1.08%; range: 95.6%–100%). Conclusion: Both MATRIXX and Delta{sup 4} offer accurate and efficient verification for SRS/SBRT plans. The results measured by MATRIXX and Delta{sup 4} dosimetry systems are similar for SRS/SBRT performed with the VMAT technique.

SU-E-T-228: Liquid Ionisation Chamber Array and MicroDiamond Measurements with the CyberKnife System

International Nuclear Information System (INIS)

Poppinga, D; Looe, H; Stelljes, T; Poppe, B; Blanck, O; Harder, D

2014-01-01

Purpose: The aim of this study was to measure the dose profile and output factors with a CyberKnife accelerator using a TM60019 microDiamond detector and a 1000SRS liquid chamber array (both PTW Freiburg, Germany). Methods: An MP3 water phantom (PTW, Freiburg) was positioned along the robotic world coordinate system. The TM60019 detector was adjusted to the center of the according fields and the semiconductor axis was aligned with the beam direction. Profiles at 5cm water depth and SSD = 80 cm were measured along the robotic x axis and y axis for the cylindrical collimators of the CyberKnife (diameter 60, 50, 40, 30, 20, 15, 12.5, 10, 7.5 and 5mm). To determine the output factors the dose profile was measured at 0.1 mm steps around the field center to find the maximum dose value. The liquid chamber array (1000SRS) measurement was performed with the same setup, but with RW3 buildup. Results: The 1000SRS measurements closely conform with the TM60019 profile measurement in all profile regions and for all collimator sizes. The profile measurement is influenced by the almost equal spatial resolution of the TM60019 detector (radius of the sensitive area 1.1mm) and of the 1000SRS liquid chamber array (single chamber width 2.3mm). The measured dose profiles have not been corrected for this limited spatial resolution. Rather we purpose to consider that spatial dose averaging over 2 mm wide regions might be justified in view of patient positioning inaccuracies and of the spaces in tissue participating in the biological radiation responses. Conclusion: The 1000SRS data points conform with the TM60019 profile measurements at all profile regions showing the applicability of liquid ion chamber arrays with the CyberKnife system

SU-E-T-228: Liquid Ionisation Chamber Array and MicroDiamond Measurements with the CyberKnife System

Energy Technology Data Exchange (ETDEWEB)

Poppinga, D; Looe, H; Stelljes, T; Poppe, B [University of Oldenburg, Oldenburg, Lower Saxony (Germany); Blanck, O [CyberKnife Zentrum Norddeutschland, Guestrow (Germany); Harder, D [Georg August University, Goettingen, Niedersachsen (Germany)

2014-06-01

Purpose: The aim of this study was to measure the dose profile and output factors with a CyberKnife accelerator using a TM60019 microDiamond detector and a 1000SRS liquid chamber array (both PTW Freiburg, Germany). Methods: An MP3 water phantom (PTW, Freiburg) was positioned along the robotic world coordinate system. The TM60019 detector was adjusted to the center of the according fields and the semiconductor axis was aligned with the beam direction. Profiles at 5cm water depth and SSD = 80 cm were measured along the robotic x axis and y axis for the cylindrical collimators of the CyberKnife (diameter 60, 50, 40, 30, 20, 15, 12.5, 10, 7.5 and 5mm). To determine the output factors the dose profile was measured at 0.1 mm steps around the field center to find the maximum dose value. The liquid chamber array (1000SRS) measurement was performed with the same setup, but with RW3 buildup. Results: The 1000SRS measurements closely conform with the TM60019 profile measurement in all profile regions and for all collimator sizes. The profile measurement is influenced by the almost equal spatial resolution of the TM60019 detector (radius of the sensitive area 1.1mm) and of the 1000SRS liquid chamber array (single chamber width 2.3mm). The measured dose profiles have not been corrected for this limited spatial resolution. Rather we purpose to consider that spatial dose averaging over 2 mm wide regions might be justified in view of patient positioning inaccuracies and of the spaces in tissue participating in the biological radiation responses. Conclusion: The 1000SRS data points conform with the TM60019 profile measurements at all profile regions showing the applicability of liquid ion chamber arrays with the CyberKnife system.

RANGE AND DISTRIBUTION OF TECHNETIUM KD VALUES IN THE SRS SUBSURFACE ENVIRONMENT

International Nuclear Information System (INIS)

Kaplan, D.

2008-01-01

Performance assessments (PAs) are risk calculations used to estimate the amount of low-level radioactive waste that can be disposed at DOE sites. Distribution coefficients (K d values) are input parameters used in PA calculations to provide a measure of radionuclide sorption to sediment; the greater the K d value, the greater the sorption and the slower the estimated movement of the radionuclide through sediment. Understanding and quantifying K d value variability is important for estimating the uncertainty of PA calculations. Without this information, it is necessary to make overly conservative estimates about the possible limits of K d values, which in turn may increase disposal costs. Finally, technetium is commonly found to be amongst the radionuclides posing potential risk at waste disposal locations because it is believed to be highly mobile in its anionic form (pertechnetate, TcO 4 - ), it exists in relatively high concentrations in SRS waste, and it has a long half-life (213,000 years). The objectives of this laboratory study were to determine under SRS environmental conditions: (1) whether and to what extent TcO 4 - sorbs to sediments, (2) the range of Tc K d values, (3) the distribution (normal or log-normal) of Tc K d values, and (4) how strongly Tc sorbs to SRS sediments through desorption experiments. Objective 3, to identify the Tc K d distribution is important because it provides a statistical description that influences stochastic modeling of estimated risk. The approach taken was to collect 26 sediments from a non-radioactive containing sediment core collected from E-Area, measure Tc K d values and then perform statistical analysis to describe the measured Tc K d values. The mean K d value was 3.4 ± 0.5 mL/g and ranged from -2.9 to 11.2 mL/g. The data did not have a Normal distribution (as defined by the Shapiro-Wilk's Statistic) and had a 95-percentile range of 2.4 to 4.4 mL/g. The E-Area subsurface is subdivided into three hydrostratigraphic

Heavy metal removal and recovery using microorganisms. Volume 1, State-of-the-art and potential applications at the SRS

Energy Technology Data Exchange (ETDEWEB)

Wilde, E.W. [Westinghouse Savannah River Co., Aiken, SC (United States); Benemann, J.R. [Benemann (J.R.), Pinole, CA (United States)

1991-02-01

Microorganisms -- bacteria, fungi, and microalgae -- can accumulate relatively large amounts of toxic heavy metals and radionuclides from the environment. These organisms often exhibit specificity for particular metals. The metal content of microbial biomass can be a substantial fraction of total dry weight with concentration factors (metal in dry biomass to metal in solution) exceeding one million in some cases. Both living and inert (dead) microbial biomass can be used to reduce heavy metal concentrations in contaminated waters to very low levels -- parts per billion and even lower. In many respects (e.g. specificity, residual metal concentrations, accumulation factors, and economics) microbial bioremoval processes can be superior to conventional processes, such as ion exchange and caustic (lime or hydroxide) precipitation for heavy metals removal from waste and contaminated waters. Thus, bioremoval could be developed to contribute to the clean-up of wastes at the Savannah River Site (SRS) and other DOE facilities. However, the potential advantages of bioremoval processes must still be developed into practical operating systems. A detailed review of the literature suggests that appropriate bioremoval processes could be developed for the SRS. There is great variability from one biomass source to another in bioremoval capabilities. Bioremoval is affected by pH, other ions, temperature, and many other factors. The biological (living vs. dead) and physical (immobilized vs. dispersed) characteristics of the biomass also greatly affect metal binding. Even subtle differences in the microbial biomass, such as the conditions under which it was cultivated, can have major effects on heavy metal binding.

Inline Monitors for Measuring Cs-137 in the SRS Caustic Side Solvent Extraction Process

Energy Technology Data Exchange (ETDEWEB)

Casella, V

2006-04-24

The Department of Energy (DOE) selected Caustic-Side Solvent Extraction (CSSX) as the preferred technology for the removal of radioactive cesium from High-Level Waste (HLW) at the Savannah River Site (SRS). Before the full-scale Salt Waste Processing Facility (SWPF) becomes operational, a portion of dissolved saltcake waste will be processed through a Modular CSSX Unit (MCU). The MCU employs the CSSX process, a continuous process that uses a novel solvent to extract cesium from waste and concentrate it in dilute nitric acid. Of primary concern is Cs-137 which makes the solution highly radioactive. Since the MCU does not have the capacity to wait for sample results while continuing to operate, the Waste Acceptance Strategy is to perform inline analyses. Gamma-ray monitors are used to: measure the Cs-137 concentration in the decontaminated salt solution (DSS) before entering the DSS Hold Tank; measure the Cs-137 concentration in the strip effluent (SE) before entering the SE Hold Tank; and verify proper operation of the solvent extraction system by verifying material balance within the process. Since this gamma ray monitoring system application is unique, specially designed shielding was developed and software was written and acceptance tested by Savannah River National Laboratory (SRNL) personnel. The software is a LabView-based application that serves as a unified interface for controlling the monitor hardware and communicating with the host Distributed Control System. This paper presents the design, fabrication and implementation of this monitoring system.

Systems Engineering in the Development and Implementation of the Savannah River Site Transuranic Waste Disposition Program

International Nuclear Information System (INIS)

Fayfich, R.R.

1999-01-01

The use of systems engineering facilitated the strategic planning and implementation of the Savannah River Site (SRS) transuranic waste disposal program. This application represented the first SRS use of systems engineering in the pre-program planning stages during the development of a comprehensive strategic plan for the disposal of transuranic waste at the Department of Energy Waste Isolation Pilot Plant (WIPP) in Carlsbad, New Mexico. The use of systems engineering focused the efforts of the technical experts to devise a three initiative plan for the disposal of transuranic waste where previous efforts failed. Continued application of systems engineering facilitated the further development and implementation of the first initiative outlined in the strategic plan, i.e., set-up the program and process to begin to characterize and ship waste to the WIPP.This application of systems engineering to the transuranic waste program represented the first opportunity at the SRS for a comprehensive usage of systems engineering at all program levels. The application was initiated at the earliest possible point in the program development, i.e., strategic planning, and successively was used in detailed development and implementation of the program. Systems engineering successfully focused efforts to produce a comprehensive plan for the disposal of SRS transuranic waste at the WIPP, and facilitated development of the SRS capability and infrastructure to characterize, certify, and ship waste

Rapid Separation Methods to Characterize Actinides and Metallic Impurities in Plutonium Scrap Materials at SRS

International Nuclear Information System (INIS)

Maxwell, S.L. III; Jones, V.D.

1998-07-01

The Nuclear Materials Stabilization and Storage Division at SRS plans to stabilize selected plutonium scrap residue materials for long term storage by dissolution processing and plans to stabilize other plutonium vault materials via high-temperature furnace processing. To support these nuclear material stabilization activities, the SRS Analytical Laboratories Department (ALD) will provide characterization of materials required prior to the dissolution or the high-firing of these materials. Lab renovations to install new analytical instrumentation are underway to support these activities that include glove boxes with simulated-process dissolution and high- pressure microwave dissolution capability. Inductively-coupled plasma atomic emission spectrometry (ICP-AES), inductively- coupled mass spectrometry (ICP-MS) and thermal-ionization mass spectrometry (TIMS) will be used to measure actinide isotopics and metallic impurities. New high-speed actinide separation methods have been developed that will be applied to isotopic characterization of nuclear materials by TIMS and ICP-MS to eliminate isobaric interferences between Pu-238 /U- 238 and Pu-241/Am-241. TEVA Resin, UTEVA Resin, and TRU Resin columns will be used with vacuum-assisted flow rates to minimize TIMS and ICP-MS sample turnaround times. For metallic impurity analysis, rapid column removal methods using UTEVA Resin, AGMP-1 anion resin and AG MP-50 cation resin have also been developed to remove plutonium and uranium matrix interferences prior to ICP-AES and ICP- MS measurements

Efficient Use of Clickers: A Mixed-Method Inquiry with University Teachers

Science.gov (United States)

Cheung, George; Wan, Kelvin; Chan, Kevin

2018-01-01

With the advancement of information technology and policies encouraging interactivities in teaching and learning, the use of students' response system (SRS), commonly known as clickers, has experienced substantial growth in recent years. The reported effectiveness of SRS has varied. Based on the framework of technological-pedagogical-content…

Mineralization of soil-aged isoproturon and isoproturon metabolites by Sphingomonas sp. strain SRS2.

Science.gov (United States)

Johannesen, Helle; Sørensen, Sebastian R; Aamand, Jens

2003-01-01

The aim of the study was to determine the effect of aging of the herbicide isoproturon and its metabolites monodesmethyl-isoproturon and 4-isopropyl-aniline in agricultural soil on their availability to the degrading bacterium Sphingomonas sp. strain SRS2. The 14C-ring-labeled isoproturon, monodesmethyl-isoproturon, and 4-isopropyl-aniline were added to sterilized soil and stored for 1, 49, 71, or 131 d before inoculation with strain SRS2. The availability of the compounds was estimated from the initial mineralization and the amount of 14CO2 recovered after 120 d of incubation. Aging in soil for 131 d reduced the initial mineralization of isoproturon and monodesmethyl-isoproturon and, in the case of isoproturon, also reduced the recovery of 14CO2. Initial mineralization and recovery of 14CO2 from aged 4-isopropyl-aniline were slightly reduced, but less 14CO2 was generally produced than with isoproturon or monodesmethyl-isoproturon. Thus, recovery of 14CO2 from 14C-isoproturon and 14C-monodesmethyl-isoproturon was 50.7 to 64.4% of the initially added 14C, while recovery from 14C-4-isopropyl-aniline was only 11.7 to 17.0%. Sorption measurements revealed similar Freundlich constants (K(f)) for isoproturon and monodesmethyl-isoproturon, whereas K(f) for 4-isopropyl-aniline was more than fivefold greater. The findings imply that in soil, partial degradation of isoproturon to 4-isopropyl-aniline may lead to reduced mineralization of the herbicide due to sorption of the aniline moiety.

SU-D-BRA-02: Motion Assessment During Open Face Mask SRS Using CBCT and Surface Monitoring

International Nuclear Information System (INIS)

Williams, BB; Fox, CJ; Hartford, AC; Gladstone, DJ

2016-01-01

Purpose: To assess the robustness of immobilization using open-face mask technology for linac-based stereotactic radiosurgery (SRS) with multiple non-coplanar arcs via repeated CBCT acquisition, with comparison to contemporaneous optical surface tracking data. Methods: 25 patients were treated in open faced masks with cranial SRS using 3–4 non-coplanar arcs. Repeated CBCT imaging was performed to verify the maintenance of proper patient positioning during treatment. Initial patient positioning was performed based on prescribed shifts and optical surface tracking. Positioning refinements employed rigid 3D-matching of the planning CT and CBCT images and were implemented via automated 6DOF couch control. CBCT imaging was repeated following the treatment of all non-transverse beams with associated couch kicks. Detected patient translations and rotations were recorded and automatically corrected. Optical surface tracking was applied throughout the treatments to monitor motion, and this contemporaneous patient positioning data was recorded to compare against CBCT data and 6DOF couch adjustments. Results: Initial patient positions were refined on average by translations of 3±1mm and rotations of ±0.9-degrees. Optical surface tracking corroborated couch corrections to within 1±1mm and ±0.4-degrees. Following treatment of the transverse and subsequent superior-oblique beam, average translations of 0.6±0.4mm and rotations of ±0.4-degrees were reported via CBCT, with optical surface tracking in agreement to within 1.1±0.6mm and ±0.6-degrees. Following treatment of the third beam, CBCT indicated additional translations of 0.4±0.2mm and rotations of ±0.3-degrees. Cumulative couch corrections resulted in 0.7 ± 0.4mm average magnitude translations and rotations of ±0.4-degrees. Conclusion: Based on CBCT measurements of patients during SRS, the open face mask maintained patient positioning to within 1.5mm and 1-degree with >95% confidence. Patient positioning

SU-D-BRA-02: Motion Assessment During Open Face Mask SRS Using CBCT and Surface Monitoring

Energy Technology Data Exchange (ETDEWEB)

Williams, BB; Fox, CJ; Hartford, AC; Gladstone, DJ [Dartmouth-Hitchcock Medical Center, Lebanon, NH (Lebanon)

2016-06-15

Purpose: To assess the robustness of immobilization using open-face mask technology for linac-based stereotactic radiosurgery (SRS) with multiple non-coplanar arcs via repeated CBCT acquisition, with comparison to contemporaneous optical surface tracking data. Methods: 25 patients were treated in open faced masks with cranial SRS using 3–4 non-coplanar arcs. Repeated CBCT imaging was performed to verify the maintenance of proper patient positioning during treatment. Initial patient positioning was performed based on prescribed shifts and optical surface tracking. Positioning refinements employed rigid 3D-matching of the planning CT and CBCT images and were implemented via automated 6DOF couch control. CBCT imaging was repeated following the treatment of all non-transverse beams with associated couch kicks. Detected patient translations and rotations were recorded and automatically corrected. Optical surface tracking was applied throughout the treatments to monitor motion, and this contemporaneous patient positioning data was recorded to compare against CBCT data and 6DOF couch adjustments. Results: Initial patient positions were refined on average by translations of 3±1mm and rotations of ±0.9-degrees. Optical surface tracking corroborated couch corrections to within 1±1mm and ±0.4-degrees. Following treatment of the transverse and subsequent superior-oblique beam, average translations of 0.6±0.4mm and rotations of ±0.4-degrees were reported via CBCT, with optical surface tracking in agreement to within 1.1±0.6mm and ±0.6-degrees. Following treatment of the third beam, CBCT indicated additional translations of 0.4±0.2mm and rotations of ±0.3-degrees. Cumulative couch corrections resulted in 0.7 ± 0.4mm average magnitude translations and rotations of ±0.4-degrees. Conclusion: Based on CBCT measurements of patients during SRS, the open face mask maintained patient positioning to within 1.5mm and 1-degree with >95% confidence. Patient positioning

Improvements to the Hunter Dose tracking system

Energy Technology Data Exchange (ETDEWEB)

Whiteside, T. S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Aucott, T. J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Brand, A. D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Diprete, D. P. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2017-07-01

Since 1965, the Savannah River Site (SRS) has conducted deer hunts which are open to the general public. SRS performs field monitoring for cesium-137 (Cs-137) of each harvested animal to determine whether the animal may be released to the hunter. A new field system for measuring Cs-137 in the harvested animals has been developed. The system incorporates numerous enhancements compared to the original system. The original system was composed of two Ludlum Measurements scalar-driven 2 inch x 2 inch sodium iodide counters, while the new system is based on a single Ametek Ortec Digibase-driven 2 inch x 4 inch x 16 inch sodium iodide gamma spectrometer. The new system includes a series of easy-to-assemble stainless steel encapsulated lead shields. The combination of the larger detector size and lead shielding improved the detection limit of the new system by a factor of approximately three compared to the original system. This lower detection limit allows for a larger number of measurements to be directly compared to the laboratory results, in cases where animal portions have been sampled. The results from developing and using this system are presented as well as recommendations on improvements to the overall field monitoring of the SRS hunts.

Behavior of mercury, lead, cesium, and uranyl ions on four SRS soils

International Nuclear Information System (INIS)

Bibler, J.P.; Marson, D.B.

1992-01-01

Samples of four Savannah River Site (SRS) soils were tested for sorption behavior with Hg 2+ , Pb 2+ , UO 2 2+ , and Cs + ions. The purpose of the study was to determine the selectivity of the different soils for these ions alone and in the presence of the competing cations, H + and Ca 2+ . Distribution constants, Kd's, for the test ions in various solutions have been determined for the four soils. In general, sorption by all of the soils appeared to be more complex than a simple ion exchange or adsorption process. In particular, the presence of organic matter in soil increased the capacity of the soil due to its chelating ability. Similar soils did not react similarly toward each metal cation

Rapid response systems.

Science.gov (United States)

Lyons, Patrick G; Edelson, Dana P; Churpek, Matthew M

2018-07-01

Rapid response systems are commonly employed by hospitals to identify and respond to deteriorating patients outside of the intensive care unit. Controversy exists about the benefits of rapid response systems. We aimed to review the current state of the rapid response literature, including evolving aspects of afferent (risk detection) and efferent (intervention) arms, outcome measurement, process improvement, and implementation. Articles written in English and published in PubMed. Rapid response systems are heterogeneous, with important differences among afferent and efferent arms. Clinically meaningful outcomes may include unexpected mortality, in-hospital cardiac arrest, length of stay, cost, and processes of care at end of life. Both positive and negative interventional studies have been published, although the two largest randomized trials involving rapid response systems - the Medical Early Response and Intervention Trial (MERIT) and the Effect of a Pediatric Early Warning System on All-Cause Mortality in Hospitalized Pediatric Patients (EPOCH) trial - did not find a mortality benefit with these systems, albeit with important limitations. Advances in monitoring technologies, risk assessment strategies, and behavioral ergonomics may offer opportunities for improvement. Rapid responses may improve some meaningful outcomes, although these findings remain controversial. These systems may also improve care for patients at the end of life. Rapid response systems are expected to continue evolving with novel developments in monitoring technologies, risk prediction informatics, and work in human factors. Copyright © 2018 Elsevier B.V. All rights reserved.

Chemical inventory control program for mixed and hazardous waste facilities at SRS

International Nuclear Information System (INIS)

Ades, M.J.; Vincent, A.M. III.

1997-01-01

Mixed Waste (MW) and Hazardous Waste (HW) are being stored at the Savannah River Site (SRS) pending onsite and/or offsite treatment and disposal. The inventory control for these wastes has recently been brought under Technical Safety Requirements (TSR) in accordance with DOE Order 5480.22. With the TSRs was the question of the degree of rigor with which the inventory is to be tracked, considering that the variety of chemicals present, or that could be present, numbers in the hundreds. This paper describes the graded approach program to track Solid Waste (SW) inventories relative to TSRs. The approach uses a ratio of the maximum anticipated chemical inventory to the permissible inventory in accordance with Emergency Response Planning Guideline (ERPG) limits for on- and off-site receptors. A specific threshold ratio can then be determined. The chemicals above this threshold ratio are to be included in the chemical inventory control program. The chemicals that fall below the threshold ratio are managed in accordance with existing practice per State and RCRA hazardous materials requirements. Additionally, the facilities are managed in accordance with process safety management principles, specifically using process hazards analyses, which provides safety assurance for even the small quantities that may be excluded from the formal inventory control program. The method yields a practical approach to chemical inventory control, while maintaining appropriate chemical safety margins. The resulting number of specific chemicals that require inclusion in a rigorous inventory control program is greatly reduced by about 80%, thereby resulting in significant reduction in chemical data management while preserving appropriate safety margins

Draft Genome Sequence of Isoproturon-Mineralizing Sphingomonas sp. SRS2, Isolated from an Agricultural Field in the United Kingdom.

Science.gov (United States)

Nielsen, Tue Kjærgaard; Sørensen, Sebastian R; Hansen, Lars Hestbjerg

2015-05-28

Sphingomonas sp. SRS2 was the first described pure strain that is capable of mineralizing the phenylurea herbicide isoproturon and some of its related compounds. This strain has been studied thoroughly and shows potential for bioremediation purposes. We present the draft genome sequence of this bacterium, which will aid future studies. Copyright © 2015 Nielsen et al.

Results of Macroinvertebrate Sampling Conducted at 33 SRS Stream Locations, July--August 1993

Energy Technology Data Exchange (ETDEWEB)

Specht, W.L.

1994-12-01

In order to assess the health of the macroinvertebrate communities of SRS streams, the macroinvertebrate communities at 30 stream locations on SRS were sampled during the summer of 1993, using Hester-Dendy multiplate samplers. In addition, three off-site locations in the Upper Three Runs drainage were sampled in order to assess the potential for impact from off-site activities. In interpreting the data, it is important to recognize that these data were from a single set of collections. Macroinvertebrate communities often undergo considerable temporal variation, and are also greatly influenced by such factors as water depth, water velocity, and available habitat. These stations were selected with the intent of developing an on-going sampling program at a smaller number of stations, with the selection of the stations to be based largely upon the results of this preliminary sampling program. When stations within a given stream showed similar results, fewer stations would be sampled in the future. Similarly, if a stream appeared to be perturbed, additional stations or chemical analyses might be added so that the source of the perturbation could be identified. In general, unperturbed streams will contain more taxa than perturbed streams, and the distribution of taxa among orders or families will differ. Some groups of macroinvertebrates, such as Ephemeroptera (mayflies), Plecoptera (stoneflies) and Trichoptera (caddisflies), which are collectively called EPT taxa, are considered to be relatively sensitive to most kinds of stream perturbation; therefore a reduced number of EPT taxa generally indicates that the stream has been subject to chemical or physical stressors. In coastal plain streams, EPT taxa are generally less dominant than in streams with rocky substrates, while Chironomidae (midges) are more abundant. (Abstract Truncated)

Intergranular stress corrosion cracking: A rationalization of apparent differences among stress corrosion cracking tendencies for sensitized regions in the process water piping and in the tanks of SRS reactors

International Nuclear Information System (INIS)

Louthan, M.R.

1990-01-01

The frequency of stress corrosion cracking in the near weld regions of the SRS reactor tank walls is apparently lower than the cracking frequency near the pipe-to-pipe welds in the primary cooling water system. The difference in cracking tendency can be attributed to differences in the welding processes, fabrication schedules, near weld residual stresses, exposure conditions and other system variables. This memorandum discusses the technical issues that may account the differences in cracking tendencies based on a review of the fabrication and operating histories of the reactor systems and the accepted understanding of factors that control stress corrosion cracking in austenitic stainless steels

SU-E-T-757: TMRs Calculated From PDDs Versus the Direct Measurements for Small Field SRS Cones

International Nuclear Information System (INIS)

Li, H; Zhong, H; Song, K; Qin, Y; Snyder, K; Gordon, J; Chetty, I; Wen, N

2015-01-01

Purpose: To investigate the variation of TMR for SRS cones obtained by TMR scanning, calculation from PDDs, and point measurements. The obtained TMRs were also compared to the representative data from the vendor. Methods: TMRs for conical cones of 4, 5, 7.5, 10, 12.5, 15, and 17.5 mm diameter (jaws set to 5×5 cm) were obtained for 6X FFF and 10X FFF energies on a Varian Edge linac. TMR scanning was performed with a Sun Nuclear 3D scanner and Edge detector at 100 cm SDD. TMR point measurements were measured with a Wellhofer tank and Edge detector, at multiple depths from 0.5 to 20 cm and 100 cm SDD. PDDs for converting to TMR were scanned with a Wellhofer system and SFD detector. The formalism of converting PDD to TMR, given in Khan’s book (4th Edition, p.161) was applied. Sp values at dmax were obtained by measuring Scp and Sc of the cones (jaws set to 5×5 cm) using the Edge detector, and normalized to the 10×10 cm field. Results: Along the central axis beyond dmax, the RMS and maximum percent difference of TMRs obtained with different methods were as follows: (a) 1.3% (max=3.5%) for the calculated TMRs from PDDs versus direct scanning; (b) 1.2% (max=3.3%) for direct scanning versus point measurement; (c) 1.8% (max=5.1%) for the calculated versus point measurements; (d) 1.0% (max=3.6%) for direct scanning versus vendor data; (e) 1.6% (max=7.2%) for the calculated versus vendor data. Conclusion: The overall accuracy of TMRs calculated from PDDs was comparable with that of direct scanning. However, the uncertainty at depths greater than 20 cm, increased up to 5% when compared to point measurements. This issue must be considered when developing a beam model for small field SRS planning using cones

SU-E-P-16: A Feasibility Study of Using Eclipse AAA for SRS Treatement

International Nuclear Information System (INIS)

Lim, S; LoSasso, T

2015-01-01

Purpose: To commission Varian Eclipse AAA for SRS treatment and compare the accuracy with Brainlab iPlan system for clinical cases measured with radiochromic film. Methods: A 6MV AAA clinical model for a Varian TrueBeam STx is used as baseline. The focal spot and field size of the baseline model(BASE) are (1.75,0.75) and 40×40cm 2 respectively. Maximum field sizes, output factors(S t ), FWHM focal spot and secondary source sizes are systematically adjusted to obtain an optimized model(OPT) by comparing the calculated PDD’s, profiles, and output factors with measurements taken with a stereotactic diode(SD) and, cc01 and cc04 ion chambers in Blue Phantom. In-phantom dose distributions of clinical SRS fields are calculated using the OPT and the clinical Brainlab iPlan pencil-beam. Within the 90% isodose-line(ROI), the average dose difference between the calculations and radiochromic film measurements are assessed. Results: The maximum field, focal spot and secondary source sizes for the OPT are 15×15cm 2 , (0,0), and 32.3mm respectively. The OPT St input at 1.0 and 2.0cm fields are increased by 4.5% and 1.5% from BASE. The calculated output of the BASE and OPT underestimate by 16.1%–3.2% respectively at 0.5×0.5cm 2 field and 3.1%−0.02% respectively at 1.0×1.0cm 2 field. The depth doses at 10cm are within 3.5% and 0.4% of measurements for 0.5×0.5 and 1.0×1.0cm 2 . The ROI dose of OPT and iPlan are within 1.6% and 0.6% of film measurements for 3.0cm clinical fields. For 1.0cm fields, the ROI dose of OPT underestimate 0.0–2.0% and iPlan overestimates 1.7–2.9% relative to measurements. Conclusion: The small field dose calculation of Eclipse AAA algorithm can be significantly improved by carefully adjusting the input parameters. The larger deviation of the OPT for 0.5×0.5cm 2 field from measurements can be attributed to the lowest 1.0cm field size input limit of AAA. The OPT compares reasonably well with the iPlan pencil-beam and measurements

SU-E-P-16: A Feasibility Study of Using Eclipse AAA for SRS Treatement

Energy Technology Data Exchange (ETDEWEB)

Lim, S; LoSasso, T [Memorial Sloan-Kettering Cancer Center, New York, NY (United States)

2015-06-15

Purpose: To commission Varian Eclipse AAA for SRS treatment and compare the accuracy with Brainlab iPlan system for clinical cases measured with radiochromic film. Methods: A 6MV AAA clinical model for a Varian TrueBeam STx is used as baseline. The focal spot and field size of the baseline model(BASE) are (1.75,0.75) and 40×40cm{sup 2} respectively. Maximum field sizes, output factors(S{sub t}), FWHM focal spot and secondary source sizes are systematically adjusted to obtain an optimized model(OPT) by comparing the calculated PDD’s, profiles, and output factors with measurements taken with a stereotactic diode(SD) and, cc01 and cc04 ion chambers in Blue Phantom. In-phantom dose distributions of clinical SRS fields are calculated using the OPT and the clinical Brainlab iPlan pencil-beam. Within the 90% isodose-line(ROI), the average dose difference between the calculations and radiochromic film measurements are assessed. Results: The maximum field, focal spot and secondary source sizes for the OPT are 15×15cm{sup 2}, (0,0), and 32.3mm respectively. The OPT St input at 1.0 and 2.0cm fields are increased by 4.5% and 1.5% from BASE. The calculated output of the BASE and OPT underestimate by 16.1%–3.2% respectively at 0.5×0.5cm{sup 2} field and 3.1%−0.02% respectively at 1.0×1.0cm{sup 2} field. The depth doses at 10cm are within 3.5% and 0.4% of measurements for 0.5×0.5 and 1.0×1.0cm{sup 2}. The ROI dose of OPT and iPlan are within 1.6% and 0.6% of film measurements for 3.0cm clinical fields. For 1.0cm fields, the ROI dose of OPT underestimate 0.0–2.0% and iPlan overestimates 1.7–2.9% relative to measurements. Conclusion: The small field dose calculation of Eclipse AAA algorithm can be significantly improved by carefully adjusting the input parameters. The larger deviation of the OPT for 0.5×0.5cm{sup 2} field from measurements can be attributed to the lowest 1.0cm field size input limit of AAA. The OPT compares reasonably well with the iPlan pencil

Social Responsibility Personality Differences between Male and Female Communicators.

Science.gov (United States)

Hantz, Alan M.; Wright, Donald K.

A study was conducted to explore in what ways, if any, male public relations practitioners differ from their female counterparts in their level of social responsibility. Subjects were 105 public relations practitioners (60% female and 40% male) and 215 college students (71% female and 29% male), who completed the Berkowitz-Lutterman SRS Scale. The…

Aqueous Transport Code Revisions Using Geographic Information Systems

International Nuclear Information System (INIS)

Chen, K.F.

2003-01-01

STREAM II, developed at the Savannah River Site (SRS) for execution on a personal computer, is an emergency response code that predicts downstream pollutant concentrations for releases from the SRS area to the Savannah River for emergency response management decision making. The STREAM II code consists of pre-processor, calculation, and post-processor modules. The pre-processor module provides a graphical user interface (GUI) for inputting the initial release data. The GUI passes the user specified data to the calculation module that calculates the pollutant concentrations at downstream locations and the transport times. The calculation module of the STREAM II adopts the transport module of the WASP5 code. WASP5 is a US Environmental Protection Agency water quality analysis program that simulates pollutant transport and fate through surface water using a finite difference method to solve the transport equation. The calculated downstream pollutant concentrations and travel times a re passed to the post-processor for display on the computer screen in graphical and tabular forms. To minimize the user's effort in the emergency situation, the required input parameters are limited to the time and date of release, type of release, location of release, amount and duration of release, and the calculation units. The user, however, could only select one of the seventeen predetermined locations. Hence, STREAM II could not be used for situations in which release locations differ from the seventeen predetermined locations. To eliminate this limitation, STREAM II has been revised to allow users to select the release location anywhere along the specified SRS main streams or the Savannah River by mouse-selection from a map displayed on the computer monitor. The required modifications to STREAM II using geographic information systems (GIS) software is discussed in this paper

The Use of "Socrative" in ESL Classrooms: Towards Active Learning

Science.gov (United States)

El Shaban, Abir

2017-01-01

The online student response system (SRS) is a technological tool that can be effectively implemented in English language classroom contexts and be used to promote students' active learning. In this qualitative study, "Socrative", a Web 2.0 software, was integrated with active learning activities and used as an SRS to explore English…

Mobilization And Characterization Of Colloids Generated From Cement Leachates Moving Through A SRS Sandy Sediment

International Nuclear Information System (INIS)

Li, D.; Roberts, K.; Kaplan, D.; Seaman, J.

2011-01-01

Naturally occurring mobile colloids are ubiquitous and are involved in many important processes in the subsurface zone. For example, colloid generation and subsequent mobilization represent a possible mechanism for the transport of contaminants including radionuclides in the subsurface environments. For colloid-facilitated transport to be significant, three criteria must be met: (1) colloids must be generated; (2) contaminants must associate with the colloids preferentially to the immobile solid phase (aquifer); and (3) colloids must be transported through the groundwater or in subsurface environments - once these colloids start moving they become 'mobile colloids'. Although some experimental investigations of particle release in natural porous media have been conducted, the detailed mechanisms of release and re-deposition of colloidal particles within natural porous media are poorly understood. Even though this vector of transport is known, the extent of its importance is not known yet. Colloid-facilitated transport of trace radionuclides has been observed in the field, thus demonstrating a possible radiological risk associated with the colloids. The objective of this study was to determine if cementitious leachate would promote the in situ mobilization of natural colloidal particles from a SRS sandy sediment. The intent was to determine whether cementitious surface or subsurface structure would create plumes that could produce conditions conducive to sediment dispersion and mobile colloid generation. Column studies were conducted and the cation chemistries of influents and effluents were analyzed by ICP-OES, while the mobilized colloids were characterized using XRD, SEM, EDX, PSD and Zeta potential. The mobilization mechanisms of colloids in a SRS sandy sediment by cement leachates were studied.

Alternative Chemical Cleaning Methods for High Level Waste Tanks: Actual Waste Testing with SRS Tank 5F Sludge

Energy Technology Data Exchange (ETDEWEB)

King, William D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Hay, Michael S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2016-08-30

Solubility testing with actual High Level Waste tank sludge has been conducted in order to evaluate several alternative chemical cleaning technologies for the dissolution of sludge residuals remaining in the tanks after the exhaustion of mechanical cleaning and sludge sluicing efforts. Tests were conducted with archived Savannah River Site (SRS) radioactive sludge solids that had been retrieved from Tank 5F in order to determine the effectiveness of an optimized, dilute oxalic/nitric acid cleaning reagent toward dissolving the bulk non-radioactive waste components. Solubility tests were performed by direct sludge contact with the oxalic/nitric acid reagent and with sludge that had been pretreated and acidified with dilute nitric acid. For comparison purposes, separate samples were also contacted with pure, concentrated oxalic acid following current baseline tank chemical cleaning methods. One goal of testing with the optimized reagent was to compare the total amounts of oxalic acid and water required for sludge dissolution using the baseline and optimized cleaning methods. A second objective was to compare the two methods with regard to the dissolution of actinide species known to be drivers for SRS tank closure Performance Assessments (PA). Additionally, solubility tests were conducted with Tank 5 sludge using acidic and caustic permanganate-based methods focused on the “targeted” dissolution of actinide species.

Measurements of stimulated-Raman-scattering-induced tilt in spectral-amplitude-coding optical code-division multiple-access systems

Science.gov (United States)

Al-Qazwini, Zaineb A. T.; Abdullah, Mohamad K.; Mokhtar, Makhfudzah B.

2009-01-01

We measure the stimulated Raman scattering (SRS)-induced tilt in spectral-amplitude-coding optical code-division multiple-access (SAC-OCDMA) systems as a function of system main parameters (transmission distance, power per chip, and number of users) via computer simulations. The results show that SRS-induced tilt significantly increases as transmission distance, power per chip, or number of users grows.

Laboratory QA/QC improvements for small drinking water systems at Savannah River Site

Energy Technology Data Exchange (ETDEWEB)

Turner, R.D.

1995-12-01

The Savannah River Site (SRS), a 310 square mile facility located near Aiken, S.C., is operated by Westinghouse Savannah River Company for the US Department of Energy. SRS has 28 separate drinking water systems with average daily demands ranging from 0.0002 to 0.5 MGD. All systems utilize treated groundwater. Until recently, the water laboratories for each system operated independently. As a result, equipment, reagents, chemicals, procedures, personnel, and quality control practices differed from location to location. Due to this inconsistency, and a lack of extensive laboratory OA/QC practices at some locations, SRS auditors were not confident in the accuracy of daily water quality analyses results. The Site`s Water Services Department addressed these concerns by developing and implementing a practical laboratory QA/QC program. Basic changes were made which can be readily adopted by most small drinking water systems. Key features of the program include: Standardized and upgraded laboratory instrumentation and equipment; standardized analytical procedures based on vendor manuals and site requirements; periodic accuracy checks for all instrumentation; creation of a centralized laboratory to perform metals digestions and chlorine colorimeter accuracy checks; off-site and on-site operator training; proper storage, inventory and shelf life monitoring for reagents and chemicals. This program has enhanced the credibility and accuracy of SRS drinking water system analyses results.

Commissioning of an APPLE-II Undulator at Daresbury Laboratory for the SRS

CERN Document Server

Clarke, James; Scott, Duncan; Shepherd, Ben; Wyles, Naomi

2005-01-01

A new variable polarisation undulator of the APPLE-II type has been designed and constructed at Daresbury Laboratory. Initial magnet testing of the 56mm period device was followed by an intensive period of shimming to improve the field quality. After this was successfully completed the undulator was installed into the SRS and tests made of the effect of the device upon the electron beam. This beam commissioning was completed in a very short space of time with the beamline being given full control of the gap and phase of the magnet within a few weeks of installation. This paper summarises the measurement of the magnet and the shimming techniques employed to improve the field quality. It also describes the effect of the device upon the stored 2 GeV electron beam and the measures taken to minimise these effects during user operations.

Phase diagrams for systems Cu2S-AIIS (AII=Mg, Ca, Sr, Ba)

International Nuclear Information System (INIS)

Andreev, O.V.; Sikerina, N.V.; Solov'eva, A.V.

2005-01-01

By the methods of physicochemical analysis phase diagrams of Cu 2 S-A II S (A II =Mg, Ca, Sr, Ba) systems are studied. The system Cu 2 S-SrS is of eutectic type with eutectic coordinates 1095 K and 21.5 mol.% of SrS. Solubility of SrS in Cu 2 S is 2 mol.% at 1095 K. Regularities of phase diagram changes of Cu 2 S-A II S (A II =Mg, Ca, Sr, Ba) system are determined. Thermodynamic analysis is done [ru

SU-F-T-573: Evaluation of EBT-XD Radiochromic Films for Verification of SBRT and SRS Treatment Delivery

Energy Technology Data Exchange (ETDEWEB)

Aubry, J; Zerouali, K [Centre hospitalier de l’Universite de Montreal, Montreal, Quebec (Canada)

2016-06-15

Purpose: To evaluate the accuracy and precision of radiochromic films EBT-XD for quality control of stereotaxic body radiation therapy (SBRT) and stereotactic radiosurgery (SRS) plan delivery. Methods: A film cut in 3×10 cm2 strips was irradiated from 0 to 20 Gy in increments of 1 to 1.5 Gy using a 15 MeV electron beam. Triple-channel film calibration was completed 24 hours later by scanning the film strips on an Epson 10000XL scanner using a well-defined protocol. Several dose measurements of increasing complexity were subsequently performed with Varian iX accelerators. Pieces of films were first irradiated in a solid water phantom with 6 MV photon beams and a static gantry to doses spanning the calibration range, either in a single field or multiple fields setup. High dose (>15 Gy per fraction) IMRT plans were then measured. Finally films were irradiated with volumetric modulated arc therapy (VMAT) plans of lung and spinal lesions with prescribed doses per fraction between 8 and 20 Gy. The dose measured with the films was compared to the calculated dose from the Eclipse planning system using the Anisotropic Analytical Algorithm (AAA). Results: 77 dose measurements were compared to either ion chamber measurements or dose calculations (reference). The average dose difference between film measurements and reference was 0.7 % and the standard deviation was 1.3%. The maximum and minimum dose differences were +3.5% and −2% in the 4 Gy to 20 Gy range. Measured dose profiles of lung and vertebra treatment plans agreed very well with the calculations. Conclusion: EBT-XD films are a useful dosimeter for quality control of SBRT and SRS plan delivery. The measurement of a full 2D dose plane with high spatial resolution and acceptable dose accuracy make it an advantageous choice compared to other detectors such as ion chambers or diodes.

Snore related signals processing in a private cloud computing system.

Science.gov (United States)

Qian, Kun; Guo, Jian; Xu, Huijie; Zhu, Zhaomeng; Zhang, Gongxuan

2014-09-01

Snore related signals (SRS) have been demonstrated to carry important information about the obstruction site and degree in the upper airway of Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) patients in recent years. To make this acoustic signal analysis method more accurate and robust, big SRS data processing is inevitable. As an emerging concept and technology, cloud computing has motivated numerous researchers and engineers to exploit applications both in academic and industry field, which could have an ability to implement a huge blue print in biomedical engineering. Considering the security and transferring requirement of biomedical data, we designed a system based on private cloud computing to process SRS. Then we set the comparable experiments of processing a 5-hour audio recording of an OSAHS patient by a personal computer, a server and a private cloud computing system to demonstrate the efficiency of the infrastructure we proposed.

SU-F-T-568: QA of a Multi-Target Multi-Dose VMAT SRS

Energy Technology Data Exchange (ETDEWEB)

Roa, D; Kuo, J [University of California, Irvine, Orange, CA (United States); Gonzales, A [Clinica Aliada contra el Cancer, Lima (Peru)

2016-06-15

Purpose: To, experimentally, corroborated the prescribed doses utilizing dosimeters (e.g. films and TLDs) that can provide high spatial resolution, allow dose measurement of multiple targets at once, and provide accurate dosimetric results. Methods: A single-isocenter 6FFF SRS VMAT plan consisting of one 358° arc at 0° couch angle and four 179° arcs at 30°, 60°, 330° and 300° couch angles respectively, was generated in ECLIPSE v.11 using a Rando-Alderson anthropomorphic head phantom CT study. This plan was a reproduction of a clinical plan generated for a stage-IV melanoma patient diagnosed with 19 intracranial lesions. The phantom was loaded with axially mounted (between phantom slabs) Gafchromic EBT3 film and TLDs strategically positioned within various target volumes. Film and TLDS were calibrated according to established protocols. Target prescription doses were 16 Gy (3cc≤, 3 lesions), 18 Gy (∼1–3cc, 10 lesions) and 20 Gy (≤1cc, 6 lesions). Phantom setup was verified through CBCT imaging prior to irradiation. Gafchromic films were scanned in transmission mode and TLDs were read, respectively, ∼24 hrs after irradiation. Results: Dose calibrated Gafchromic film data were compared to the ECLIPSE calculated data using a 3% / 3mm gamma function analysis. Results for the gamma values were 96–99% in agreement with the calculated data and with 84–90% of the film pixels within the 3% dose difference. TLD data showed a dose difference of 0.4–8% while the film data for those same locations yielded a difference of 0.4–4%. It was observed that the highest dose discrepancies correlated with the location of the small volume targets. Conclusion: Overall this study corroborated that a VMAT SRS treatment, employing various treatment table rotations and arcs, to multiple intracranial lesions with multiple dose prescriptions can be delivered accurately with the existing radiotherapy technology.

SU-F-SPS-10: The Dosimetric Comparison of GammaKnife and Cyberknife Treatment Plans for Brain SRS Treatment

International Nuclear Information System (INIS)

Sanli, E; Mabhouti, H; Cebe, M; Codel, G; Pacaci, P; Serin, E; Kucuk, N; Kucukmorkoc, E; Doyuran, M; Canoglu, D; Altinok, A; Acar, H; Caglar Ozkok, H

2016-01-01

Purpose: Brain stereotactic radiosurgery (SRS) involves the use of precisely directed, single session radiation to create a desired radiobiologic response within the brain target with acceptable minimal effects on surrounding structures or tissues. In this study, the dosimetric comparison of GammaKnife perfection and Cyberknife M6 treatment plans were made. Methods: Treatment plannings were done for GammaKnife perfection unit using Gammaplan treatment planning system (TPS) on the CT scan of head and neck randophantom simulating the treatment of sterotactic treatments for one brain metastasis. The dose distribution were calculated using TMR 10 algorithm. The treatment planning for the same target were also done for Cyberknife M6 machine using Multiplan (TPS) with Monte Carlo algorithm. Using the same film batch, the net OD to dose calibration curve was obtained using both machine by delivering 0- 800 cGy. Films were scanned 48 hours after irradiation using an Epson 1000XL flatbed scanner. Dose distribution were measured using EBT3 film dosimeter. The measured and calculated doses were compared. Results: The dose distribution in the target and 2 cm beyond the target edge were calculated on TPSs and measured using EBT3 film. For cyberknife treatment plans, the gamma analysis passing rates between measured and calculated dose distributions were 99.2% and 96.7% for target and peripheral region of target respectively. For gammaknife treatment plans, the gamma analysis passing rates were 98.9% and 93.2% for target and peripheral region of target respectively. Conclusion: The study shows that dosimetrically comparable plans are achievable with Cyberknife and GammaKnife. Although TMR 10 algorithm predicts the target dose

SU-F-SPS-10: The Dosimetric Comparison of GammaKnife and Cyberknife Treatment Plans for Brain SRS Treatment

Energy Technology Data Exchange (ETDEWEB)

Sanli, E; Mabhouti, H; Cebe, M; Codel, G; Pacaci, P; Serin, E; Kucuk, N; Kucukmorkoc, E; Doyuran, M; Canoglu, D; Altinok, A; Acar, H; Caglar Ozkok, H [Medipol University, Istanbul, Istanbul (Turkey)

2016-06-15

Purpose: Brain stereotactic radiosurgery (SRS) involves the use of precisely directed, single session radiation to create a desired radiobiologic response within the brain target with acceptable minimal effects on surrounding structures or tissues. In this study, the dosimetric comparison of GammaKnife perfection and Cyberknife M6 treatment plans were made. Methods: Treatment plannings were done for GammaKnife perfection unit using Gammaplan treatment planning system (TPS) on the CT scan of head and neck randophantom simulating the treatment of sterotactic treatments for one brain metastasis. The dose distribution were calculated using TMR 10 algorithm. The treatment planning for the same target were also done for Cyberknife M6 machine using Multiplan (TPS) with Monte Carlo algorithm. Using the same film batch, the net OD to dose calibration curve was obtained using both machine by delivering 0- 800 cGy. Films were scanned 48 hours after irradiation using an Epson 1000XL flatbed scanner. Dose distribution were measured using EBT3 film dosimeter. The measured and calculated doses were compared. Results: The dose distribution in the target and 2 cm beyond the target edge were calculated on TPSs and measured using EBT3 film. For cyberknife treatment plans, the gamma analysis passing rates between measured and calculated dose distributions were 99.2% and 96.7% for target and peripheral region of target respectively. For gammaknife treatment plans, the gamma analysis passing rates were 98.9% and 93.2% for target and peripheral region of target respectively. Conclusion: The study shows that dosimetrically comparable plans are achievable with Cyberknife and GammaKnife. Although TMR 10 algorithm predicts the target dose.

The National Centre of Systems Reliability and some aspects of its future activities

International Nuclear Information System (INIS)

Bourne, A.J.

1975-01-01

The National Centre of Systems Reliability (NCSR) has been set up to enhance the work of the Systems Reliability Service (SRS), which during its four years of operation by the UKAEA has offered to industry expertise in the quantification of reliability of systems in various technological applications. An outline is presented of the background to the establishment of the NCSR, including a brief summary of the work of the SRS. Certain aspects of the future activities of the NCSR particularly in relation to research and collaboration with universities are discussed. (U.K.)

The Front-End Concentrator card for the RD51 Scalable Readout System

International Nuclear Information System (INIS)

Toledo, J; Esteve, R; Monzó, J M; Tarazona, A; Muller, H; Martoiu, S

2011-01-01

Conventional readout systems exist in many variants since the usual approach is to build readout electronics for one given type of detector. The Scalable Readout System (SRS) developed within the RD51 collaboration relaxes this situation considerably by providing a choice of frontends which are connected over a customizable interface to a common SRS DAQ architecture. This allows sharing development and production costs among a large base of users as well as support from a wide base of developers. The Front-end Concentrator card (FEC), a RD51 common project between CERN and the NEXT Collaboration, is a reconfigurable interface between the SRS online system and a wide range of frontends. This is accomplished by using application-specific adapter cards between the FEC and the frontends. The ensemble (FEC and adapter card are edge mounted) forms a 6U × 220 mm Eurocard combo that fits on a 19'' subchassis. Adapter cards exist already for the first applications and more are in development.

Results of the Level 1 probabilistic risk assessment (PRA) of internal events for heavy water production reactors

International Nuclear Information System (INIS)

Tinnes, S.P.; Cramer, D.S.; Logan, V.E.; Topp, S.V.; Smith, J.A.; Brandyberry, M.D.

1990-01-01

A full-scope probabilistic risk assessment (PRA) is being performed for the Savannah River site (SRS) production reactors. The Level 1 PRA for the K Reactor has been completed and includes the assessment of reactor systems response to accidents and estimates of the severe core melt frequency (SCMF). The internal events spectrum includes those events related directly to plant systems and safety functions for which transients or failures may initiate an accident. The SRS PRA has three principal objectives: improved understanding of SRS reactor safety issues through discovery and understanding of the mechanisms involved. Improved risk management capability through tools for assessing the safety impact of both current standard operations and proposed revisions. A quantitative measure of the risks posed by SRS reactor operation to employees and the general public, to allow comparison with declared goals and other societal risks

HASILT: An intelligent software platform for HAZOP, LOPA, SRS and SIL verification

International Nuclear Information System (INIS)

Cui, Lin; Shu, Yidan; Wang, Zhaohui; Zhao, Jinsong; Qiu, Tong; Sun, Wenyong; Wei, Zhenqiang

2012-01-01

Incomplete process hazard analysis (PHA) and poor knowledge management have been two major reasons that have caused numerous lamentable disasters in the chemical process industry (CPI). To improve PHA quality, a new integration framework that combines HAZOP, layer of protection analysis (LOPA), safety requirements specification (SRS) and safety integrity level (SIL) validation is proposed in this paper. To facilitate the integrated work flow and improve the relevant knowledge management, an intelligent software platform named HASILT has been developed by our research team. Its key components and functions are described in this paper. Furthermore, since the platform keeps all history data in a central case base and case-based reasoning is used to automatically retrieve similar old cases for helping resolve new problems, a recall opportunity is created to reduce information loss which has been cited many times as a common root cause in investigations of accidents.

Surveillance Analysis Computer System (SACS) software requirements specification (SRS)

International Nuclear Information System (INIS)

Glasscock, J.A.; Flanagan, M.J.

1995-09-01

This document is the primary document establishing requirements for the Surveillance Analysis Computer System (SACS) Database, an Impact Level 3Q system. The purpose is to provide the customer and the performing organization with the requirements for the SACS Project

Stereotactic Radiosurgery for Brainstem Metastases: An International Cooperative Study to Define Response and Toxicity

Energy Technology Data Exchange (ETDEWEB)

Trifiletti, Daniel M., E-mail: daniel.trifiletti@gmail.com [Department of Radiation Oncology, University of Virginia, Charlottesville, Virginia (United States); Lee, Cheng-Chia [Department of Neurosurgery, Neurological Institute, Taipei Veteran General Hospital, Taipei, Taiwan (China); Kano, Hideyuki; Cohen, Jonathan [Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (United States); Janopaul-Naylor, James; Alonso-Basanta, Michelle; Lee, John Y.K. [Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania (United States); Simonova, Gabriela; Liscak, Roman [Department of Radiation and Stereotactic Neurosurgery, Na Homolce Hospital, Prague (Czech Republic); Wolf, Amparo; Kvint, Svetlana [Department of Neurosurgery, New York University Lagone Medical Center, New York, New York (United States); Grills, Inga S.; Johnson, Matthew [Department of Radiation Oncology, Beaumont Health System, Royal Oak, Michigan (United States); Liu, Kang-Du; Lin, Chung-Jung [Department of Neurosurgery, Neurological Institute, Taipei Veteran General Hospital, Taipei, Taiwan (China); Mathieu, David; Héroux, France [Division of Neurosurgery, Université de Sherbrooke, Centre de recherche du CHUS, Sherbrooke, Québec (Canada); Silva, Danilo; Sharma, Mayur [Department of Neurosurgery, Cleveland Clinic, Cleveland, Ohio (United States); Cifarelli, Christopher P. [Departments of Neurosurgery and Radiation Oncology, West Virginia University, Morgantown, West Virginia (United States); and others

2016-10-01

Purpose: To pool data across multiple institutions internationally and report on the cumulative experience of brainstem stereotactic radiosurgery (SRS). Methods and Materials: Data on patients with brainstem metastases treated with SRS were collected through the International Gamma Knife Research Foundation. Clinical, radiographic, and dosimetric characteristics were compared for factors prognostic for local control (LC) and overall survival (OS) using univariate and multivariate analyses. Results: Of 547 patients with 596 brainstem metastases treated with SRS, treatment of 7.4% of tumors resulted in severe SRS-induced toxicity (grade ≥3, increased odds with increasing tumor volume, margin dose, and whole-brain irradiation). Local control at 12 months after SRS was 81.8% and was improved with increasing margin dose and maximum dose. Overall survival at 12 months after SRS was 32.7% and impacted by age, gender, number of metastases, tumor histology, and performance score. Conclusions: Our study provides additional evidence that SRS has become an option for patients with brainstem metastases, with an excellent benefit-to-risk ratio in the hands of experienced clinicians. Prior whole-brain irradiation increases the risk of severe toxicity in brainstem metastasis patients undergoing SRS.

Spontaneous Raman Scattering Diagnostics: Applications in Practical Combustion Systems. Chapter 5

Science.gov (United States)

Kojima, Jun; Viet-Nguyen, Quang; Lackner, Maximilian (Editor); Winter, Franz (Editor); Agarwal, Avinash (Editor)

2010-01-01

In this chapter, the recent advancements and practical aspects of laser SRS diagnostics have been reviewed wi til regards to applications in practical combustion systems. Clearly, SRS represents a theoretically and experimentally mature diagnostic technology that has become an essential tool for multiscalar measurements in turbulent combustion at elevated pressures. Today, time-, space-, spectrally, and even polarization-resolved S RS diagnostics is at hand, with aid from recent innovations in theoretical and technological developments on electro-optical or electromechanical devices. Whilst a linear increase in SRS signals can be expected in high-pressure systems (this is perhaps one of the most important advantages for using SRS in high-pressure systems), there are practical (often severe) restrictions associated with pressurized vessels, due mainly to the limited degree of optical access. This narrows ti,e available choice of diagnostics that can be employed at any given time. Point-wise SRS diagnostics provides the highest accuracy on the chemical species and temperature measurements, and will continue to remain a vital approach for the study in such harsh environments. The practical design considerations and hands-on set-up guide for SRS diagnostics provided in this chapter are rarely presented elsewhere. Although the second-harmonic Nd:YAG pulsed laser (532 nm), combined with pulse-stretching optics or the recently introduced White Cell-based laser, seems to be the most favored excitation source of choice by the research community, UV excitation will undoubtedly continue to be used on many occasions, and especially in sooting flames. Detection methods may be divided into ICCD-based nanosecond-gate detection or a rotary-chopper electromechanical shutter-based CCD array detection, and the levels of background flame emission in individual cases would determine this critical design choice. Here, a process of Raman signal calibration based on ti,e crosstalk matrix

A model for transient analysis of a multiple-medium confinement filter system

International Nuclear Information System (INIS)

Hyder, M.L.; Ellison, P.G.; Leonard, M.T.; Louie, D.L.Y.; Donbroski, E.L.; Wagner, K.C.

1990-01-01

A computational model is described that calculates the transient behavior of aerosol and vapor (adsorption) filter compartments such as those used in the Savannah River Site (SRS) production reactor confinement system. The principal application of the model is in the analysis of confinement response to hypothetical severe (core melt) accidents. Under these conditions, aerosol and radio-iodine deposition on filter compartments may be substantial. Attendant filter degradation mechanisms are modeled. Sample calculations are included to illustrate model performance. 6 refs., 14 figs., 1 tab

The ArcSDE GIS Dynamic Population Model Tool for Savannah River Site Emergency Response

International Nuclear Information System (INIS)

MCLANE, TRACY; JONES, DWIGHT

2005-01-01

The Savannah River Site (SRS) is a 310-square-mile Department of Energy site located near Aiken, South Carolina. With a workforce of over 10,000 employees and subcontractors, SRS emergency personnel must be able to respond to an emergency event in a timely and effective manner, in order to ensure the safety and security of the Site. Geographic Information Systems (GIS) provides the technology needed to give managers and emergency personnel the information they need to make quick and effective decisions. In the event of a site evacuation, knowing the number of on-site personnel to evacuate from a given area is an essential piece of information for emergency staff. SRS has developed a GIS Dynamic Population Model Tool to quickly communicate real-time information that summarizes employee populations by facility area and building and then generates dynamic maps that illustrate output statistics

A multicenter study of the outcomes of the surgical treatment of adolescent idiopathic scoliosis using the Scoliosis Research Society (SRS) outcome instrument.

Science.gov (United States)

Merola, Andrew A; Haher, Thomas R; Brkaric, Mario; Panagopoulos, Georgia; Mathur, Samir; Kohani, Omid; Lowe, Thomas G; Lenke, Larry G; Wenger, Dennis R; Newton, Peter O; Clements, David H; Betz, Randal R

2002-09-15

A multicenter study of the outcomes of the surgical treatment of adolescent idiopathic scoliosis using the Scoliosis Research Society Questionnaire (SRS 24). To evaluate the patient based outcome of the surgical treatment of adolescent idiopathic scoliosis. A paucity of information exists with respect to patient measures of outcome regarding the surgical treatment of adolescent idiopathic scoliosis. To our knowledge, no prospective outcome study on this topic thus far exists. Using the SRS 24 questionnaire, seven scoliosis centers agreed to prospectively assess outcome for surgically treated patients with adolescent idiopathic scoliosis. Data were collected before surgery and at 24 months after surgery. Data were analyzed using paired and independent samples t test for all seven SRS 24 questionnaire domains (Pain, General Self-Image, Postoperative Self-Image, Postoperative Function, Function From Back Condition, General Level of Activity, and Satisfaction) using Statistical Package for Social Science. The domains were analyzed with respect to the total cohort, gender, curve magnitude, and type of surgery using independent-samples t tests. A total of 242 patients were included in our analysis. A baseline preoperative pain level of 3.68 of 5 was found. This improved to 4.63 after surgery, representing an improvement of 0.95 points. Surgical intervention was associated with improving outcome when compared with preoperative status. Pain, General Self-Image, Function From Back Condition, and Level of Activity all demonstrated statistically significant improvement as compared with preoperative status (P adolescent scoliosis population. Pain scores were improved in our study population at the 2-year postsurgical follow-up. Statistically significant improvements were likewise seen in the General Self-Image, Function From Back Condition, and Level of Activity domains. The present study demonstrates the ability of surgery to improve the outcome of patients afflicted with

DESIGN OF A SYSTEM TO RETRIEVE SLUDGE FROM THE K EAST SPENT FUEL BASIN AT HANFORD

International Nuclear Information System (INIS)

Twitchell, A.L.; MacLean, G.T.; Ho, Q.T.; Fort, D.L.

2003-01-01

This paper describes the Sludge Retrieval System (SRS), which was designed to safely remove radioactive sludge from the K East spent fuel basin at the 100 K Area of the Hanford Site. Basin water and sludge have the potential to leak to the environment due to the age and condition of the basins. Since the 100 K Area spent fuel basins are located next to the Columbia River, the Spent Nuclear Fuel Project mission includes the safe removal, containment, and transportation of sludge from the basins to a secure storage location. The scope of the SRS includes: A system capable of retrieving sludge from the K East basin floor, pits, and fuel canisters; Separation of debris from sludge, where debris is defined as any material greater than 0.64 cm (0.25 in.) in diameter; Collection of sludge particles in a container that can be transported away from the basin; Modifications to the K East basin to allow installation of the SRS. The SRS was designed by Fluor Federal Services. Changes to the designed system were made by Fluor Hanford as a result of full-scale testing performed after design. This paper discusses this testing, as well as operation and control of the system. Construction and startup testing was initially scheduled to be complete by the end of December 2002. Startup of the system is now expected in April 2003

Summary of Data and Steps for Processing the 1997-2001 SRS Meteorological Database

International Nuclear Information System (INIS)

Weber, A.H.

2003-01-01

Every five years since the mid-1970s DOE has requested an update on the meteorological conditions at SRS in order to provide dose calculations for accident or routine release scenarios for onsite and offsite populations. The meteorological database includes wind speed, wind direction, temperature, dew point, and horizontal and vertical turbulence intensities. The two most recent databases prior to the current one were completed in 1998 for the time period 1992-96 (Weber, 1998) and one for 1987-91 (Parker, et. al., 1992). The current database covers the period 1997-2001. The advantage of updating the database every five years is that meteorological observations are steadily growing more complete and less subject to errors with the implementation of better electronic data archiving software and hardware, and improved data quality assurance procedures. Also, changes in the region's climate may be manifest

Shutdown of the River Water System at the Savannah River Site: Draft environmental impact statement

International Nuclear Information System (INIS)

1996-11-01

This environmental impact statement (EIS) evaluates alternative approaches to and environmental impacts of shutting down the River Water System at the Savannah River Site (SRS). Five production reactors were operated at the site.to support these facilities, the River Water System was constructed to provide cooling water to pass through heat exchangers to absorb heat from the reactor core in each of the five reactor areas (C, K, L, P, and R). The DOE Savannah River Strategic Plan directs the SRS to find ways to reduce operating costs and to determine what site infrastructure it must maintain and what infrastructure is surplus. The River Water System has been identified as a potential surplus facility. Three alternatives to reduce the River Water System operating costs are evaluated in this EIS. In addition to the No-Action Alternative, which consists of continuing to operate the River Water System, this EIS examines one alternative (the Preferred Alternative) to shut down and maintain the River Water System in a standby condition until DOE determines that a standby condition is no longer necessary, and one alternative to shut down and deactivate the River Water System. The document provides background information and introduces the River Water System at the SRS; sets forth the purpose and need for DOE action; describes the alternatives DOE is considering; describes the environment at the SRS and in the surrounding area potentially affected by the alternatives addressed and provides a detailed assessment of the potential environmental impacts of the alternatives; and identifies regulatory requirements and evaluates their applicability to the alternatives considered

Post-treatment neutrophil-to-lymphocyte ratio predicts for overall survival in brain metastases treated with stereotactic radiosurgery.

Science.gov (United States)

Chowdhary, Mudit; Switchenko, Jeffrey M; Press, Robert H; Jhaveri, Jaymin; Buchwald, Zachary S; Blumenfeld, Philip A; Marwaha, Gaurav; Diaz, Aidnag; Wang, Dian; Abrams, Ross A; Olson, Jeffrey J; Shu, Hui-Kuo G; Curran, Walter J; Patel, Kirtesh R

2018-05-30

Neutrophil-to-lymphocyte ratio (NLR) is a surrogate for systemic inflammatory response and its elevation has been shown to be a poor prognostic factor in various malignancies. Stereotactic radiosurgery (SRS) can induce a leukocyte-predominant inflammatory response. This study investigates the prognostic impact of post-SRS NLR in patients with brain metastases (BM). BM patients treated with SRS from 2003 to 2015 were retrospectively identified. NLR was calculated from the most recent full blood counts post-SRS. Overall survival (OS) and intracranial outcomes were calculated using the Kaplan-Meier method and cumulative incidence with competing risk for death, respectively. 188 patients with 328 BM treated with SRS had calculable post-treatment NLR values. Of these, 51 (27.1%) had a NLR > 6. The overall median imaging follow-up was 13.2 (14.0 vs. 8.7 for NLR ≤ 6.0 vs. > 6.0) months. Baseline patient and treatment characteristics were well balanced, except for lower rate of ECOG performance status 0 in the NLR > 6 cohort (33.3 vs. 44.2%, p = 0.026). NLR > 6 was associated with worse 1- and 2-year OS: 59.9 vs. 72.9% and 24.6 vs. 43.8%, (p = 0.028). On multivariable analysis, NLR > 6 (HR: 1.53; 95% CI 1.03-2.26, p = 0.036) and presence of extracranial metastases (HR: 1.90; 95% CI 1.30-2.78; p < 0.001) were significant predictors for worse OS. No association was seen with NLR and intracranial outcomes. Post-treatment NLR, a potential marker for post-SRS inflammatory response, is inversely associated with OS in patients with BM. If prospectively validated, NLR is a simple, systemic marker that can be easily used to guide subsequent management.

Summary report for 1990 inservice inspection (ISI) of SRS 100-L reactor tank

International Nuclear Information System (INIS)

Morrison, J.M.; Loibl, M.W.

1991-01-01

The integrity of the SRS reactor tanks is a key factor affecting their suitability for continued service since, unlike the external piping system and components, the tanks are virtually irreplaceable. Cracking in various areas of the process water piping systems has occurred beginning in about 1960 as a result of several degradation mechanisms, chiefly intergranular stress corrosion cracking (IGSCC) and chloride-induced transgranular cracking. The primary objective of this inspection was to determine if the accessible welds and selected portions of base metal in the L Reactor tank wall contain any indications of IGSCC. This inspection included areas in and beyond the weld HAZ, extending out as far as two to three inches from the centerline of the welds, plus selected areas of base metal at the intersection of the main tank vertical and mid-girth welds. No evidence of such degradation was found in any of the areas examined. Further, additional inspections were conducted of areas that had been damaged and repaired during original fabrication, and on a sample of areas containing linear indications observed during the 1986 visual inspection of the tank. No evidence of IGSCC or other service induced degradation was detected in these areas, either. The inspection was initially planned to cover a minimum of 60% of the accessible welds, plus repair areas and a sample of the indications from the 1986 visual inspection. Direction was received from DOE while the inspection was in progress to expand the scope to cover 100% of the accessible weld areas, and the plan was adjusted accordingly. Initial setup of the tank, which prior to inspection contained Mark 60B target assemblies and nearly a full charge of Mark 22 fuel assemblies, began on October 15, 1990. The inspection was completed on April 12, 1991

The TOTEM DAQ based on the Scalable Readout System (SRS)

Science.gov (United States)

Quinto, Michele; Cafagna, Francesco S.; Fiergolski, Adrian; Radicioni, Emilio

2018-02-01

The TOTEM (TOTal cross section, Elastic scattering and diffraction dissociation Measurement at the LHC) experiment at LHC, has been designed to measure the total proton-proton cross-section and study the elastic and diffractive scattering at the LHC energies. In order to cope with the increased machine luminosity and the higher statistic required by the extension of the TOTEM physics program, approved for the LHC's Run Two phase, the previous VME based data acquisition system has been replaced with a new one based on the Scalable Readout System. The system features an aggregated data throughput of 2GB / s towards the online storage system. This makes it possible to sustain a maximum trigger rate of ˜ 24kHz, to be compared with the 1KHz rate of the previous system. The trigger rate is further improved by implementing zero-suppression and second-level hardware algorithms in the Scalable Readout System. The new system fulfils the requirements for an increased efficiency, providing higher bandwidth, and increasing the purity of the data recorded. Moreover full compatibility has been guaranteed with the legacy front-end hardware, as well as with the DAQ interface of the CMS experiment and with the LHC's Timing, Trigger and Control distribution system. In this contribution we describe in detail the architecture of full system and its performance measured during the commissioning phase at the LHC Interaction Point.

Cylindrical Induction Melter Modicon Control System

International Nuclear Information System (INIS)

Weeks, G.E.

1998-04-01

In the last several years an extensive R ampersand D program has been underway to develop a vitrification system to stabilize Americium (Am) and Curium (Cm) inventories at SRS. This report documents the Modicon control system designed for the 3 inch Cylindrical Induction Melter (CIM)

SU-E-T-542: Comparison of Stereotactic Radiosurgery (SRS) of Brain Lesions Using Gamma Knife, VMAT, IMRT, and Conformal Arcs

International Nuclear Information System (INIS)

Li, S; Charpentier, P; Chan, P; Neicu, T; Miyamoto, C

2014-01-01

Purpose: To compare dose distributions in stereotactic radiation surgery of brain lesions using gamma Knife, VMAT, conformal arcs, and IMRT in order to provide an optimal treatment. Methods: Dose distributions from single shot of 4C model of Gamma Knife at the helmet collimation sizes of 4, 8, 14, and 18 mm in diameter were compared with full arcs with the square shapes of 4×4 (or 5×5), 8×8 (or 10×10), and spherical shapes of 16 or 20 mm in diameter using EDR3 films in the same gamma knife QA phantom. Plans for ten SRS cases with single and multiple lesions were created in gamma knife plans and Pinnacle plans. The external beam plans had enlarged field size by 2-mm and used single conformal full circle arc for solitary lesion and none coplanar arcs/beams for multiple lesions. Coverage, conformity index, dose to critical organs, and integral dose to the brain and nearby critical structures were compared on all plans. Structures and dose matrices were registered in a Velocity deformable image registration system. Results: Single full circle arc from Elekta beam-modulate MLC (4-mm leaf thickness) and agility MLC (5-mm leaf thickness) have larger penumbra and less flatness than that of Gamma Knife single shot. None-coplanar arcs or beams were required to achieve similar dose distribution. In general, Gamma Knife plans provided significant less integral dose than that of linac-based plans. Benefits of IMRT and VMAT versus gamma Knife and conformal arcs were not significant. Conclusion: Our dose measurement and treatment planning evaluation clearly demonstrated dose distribution differences amount current popular SRS modalities for small solitary and multiple brain lesions. The trend of using MLC shape beams or arcs to replace conventional cones should be revisited in order to keep lower integral dose if the late correlates with some radiation-induced side effects. Pilot grant from Elekta LLC

Design of a System to Retrieve Sludge from the K East Spent Fuel Basin at Hanford

International Nuclear Information System (INIS)

TWITCHELL, A.L.

2003-01-01

This paper describes the Sludge Retrieval System (SRS), which was designed to safely remove radioactive sludge from the K East spent fuel basin at the 100 K Area of the Hanford Site. Basin water and sludge have the potential to leak to the environment due to the age and condition of the basins. Since the 100 K Area spent fuel basins are located next to the Columbia River, the Spent Nuclear Fuel Project mission includes the safe removal, containment, and transportation of sludge from the basins to a secure storage location. The scope of the SRS includes: (1) a system capable of retrieving sludge from the K East basin floor, pits, and fuel canisters; (2) separation of debris from sludge, where debris is defined as any material greater than 0.64 cm (0.25 in.) in diameter; (3) collection of sludge particles in a container that can be transported away from the basin; and (4) modifications to the K East basin to allow installation of the SRS. The SRS was designed by Fluor Federal Services. Changes to the designed system were made by Fluor Hanford as a result of full-scale testing performed after design. This paper discusses this testing, as well as operation and control of the system. Construction and startup testing was initially scheduled to be complete by the end of December 2002. Startup of the system is now expected in April 2003

SPEEDUP modeling of the defense waste processing facility at the SRS

International Nuclear Information System (INIS)

Smith, F.G. III.

1997-01-01

A computer model has been developed for the dynamic simulation of batch process operations within the Defense Waste Processing Facility (DWPF) at the Savannah River Site (SRS). The DWPF chemically treats high level waste materials from the site tank farm and vitrifies the resulting slurry into a borosilicate glass for permanent disposal. The DWPF consists of three major processing areas: Salt Processing Cell (SPC), Chemical Processing Cell (CPC) and the Melt Cell. A fully integrated model of these process units has been developed using the SPEEDUP trademark software from Aspen Technology. Except for glass production in the Melt Cell, all of the chemical operations within DWPF are batch processes. Since SPEEDUP is designed for dynamic modeling of continuous processes, considerable effort was required to device batch process algorithms. This effort was successful and the model is able to simulate batch operations and the dynamic behavior of the process. The model also includes an optimization calculation that maximizes the waste content in the final glass product. In this paper, we will describe the process model in some detail and present preliminary results from a few simulation studies

Demonstration of Eastman Christensen horizontal drilling system -- Integrated Demonstration Site, Savannah River Site

International Nuclear Information System (INIS)

1992-12-01

An innovative horizontal drilling system was used to install two horizontal wells as part of an integrated demonstration project at the Savannah River Site (SRS), Aiken, South Carolina. The SRS is located in south-central South Carolina in the upper Coastal Plain physiographic province. The demonstration site is located near the A/M Area, and is currently known as the Integated Demonstration Site. The Department of Energy's Office of Technology Development initiated an integrated demonstration of innovative technologies for cleanup of volatile organic compounds (VOCS) in soils and groundwater at the SRS in 1989. The overall goal of the program is to demonstrate, at a single location, multiple technologies in the fields of drilling, characterization, monitoring, and remediation. Innovative technologies are compared to one another and to baseline technologies in terms of technical performance and cost effectiveness. Transfer of successfully demonstrated technologies and systems to DOE environmental restoration organizations, to other government agencies, and to industry is a critical part of the program

Male Prison Inmates With Gender Dysphoria: When Is Sex Reassignment Surgery Appropriate?

Science.gov (United States)

Osborne, Cynthia S; Lawrence, Anne A

2016-10-01

Gender dysphoria (GD), a feeling of persistent discomfort with one's biologic sex or assigned gender, is estimated to be more prevalent in male prison inmates than in nonincarcerated males; there may be 3000-4000 male inmates with GD in prisons in the United States. An increasing number of U.S. prison systems now offer gender dysphoric inmates diagnostic evaluation, psychotherapy, cross-sex hormone therapy, and opportunities, albeit limited, to enact their preferred gender role. Sex reassignment surgery (SRS), however, has not been offered to inmates except in response to litigation. In the first case of its kind, the California Department of Corrections and Rehabilitation recently agreed to provide SRS to an inmate and developed policy guidelines for its future provision. In other recent cases, U.S. courts have ruled that male inmates with GD are entitled to SRS when it is medically necessary. Although these decisions may facilitate the provision of SRS to inmates in the future, many U.S. prison systems will probably remain reluctant to offer SRS unless legally compelled to do so. In this review, we address the medical necessity of SRS for male inmates with GD. We also discuss eligibility criteria and the practical considerations involved in providing SRS to inmates. We conclude by offering recommendations for physicians, mental health professionals, and prison administrators, designed to facilitate provision of SRS to inmates with GD in a manner that provides humane treatment, maximizes the likelihood of successful outcomes, minimizes risk of regret, and generates data that can help inform future decisions.

Nuclear Facility Isotopic Content (NFIC) Waste Management System to provide input for safety envelope definition

International Nuclear Information System (INIS)

Genser, J.R.

1992-01-01

The Westinghouse Savannah River Company (WSRC) is aggressively applying environmental remediation and radioactive waste management activities at the US Department of Energy's Savannah River Site (SRS) to ensure compliance with today's challenging governmental laws and regulatory requirements. This report discusses a computer-based Nuclear Facility Isotopic Content (NFIC) Waste Management System developed to provide input for the safety envelope definition and assessment of site-wide facilities. Information was formulated describing the SRS ''Nuclear Facilities'' and their respective bounding inventories of nuclear materials and radioactive waste using the NFIC Waste Management System

Relation between self-image score of SRS-22 with deformity measures in female adolescent idiopathic scoliosis patients.

Science.gov (United States)

Wang, L; Wang, Y P; Yu, B; Zhang, J G; Shen, J X; Qiu, G X; Li, Y

2014-11-01

Adolescent idiopathic scoliosis (AIS) is a pathology which affects the individual's functioning in the widely understood physical, psychic, and social aspects. More attention should be paid to patients' perception of self-image when evaluating the spine deformity. The present retrospective study evaluated the associations between the deformity measures and self-image score as determined by the SRS-22 questionnaire in Chinese female AIS patients. The self-image score correlates significantly with deformity measures. The location of main curve apex and the number of curve could affect the self-image score. We retrospectively reviewed the records of 202 female patients, collected data on patient's age, body mass index, radiographic and physical measures and self-image score of SRS-22 questionnaire. According to the location of main curve apex and the number of curve, the patients were divided to different subgroups. Correlations between deformity measures and self-image score of different groups were evaluated by the Spearman correlation test. The self-image score correlated negatively with the main Cobb angle, apical vertebral translation (AVT), and razor hump height. There is no significant difference of self-image score between thoracic curve (TC) and thoracolumbar curve (TL/LC) subgroups. And the self-image scores of one-curve, two-curve and three-curve subgroups are similar. For Chinese female AIS patients in our study, self-image was found to correlate negatively with the main Cobb angle, AVT and razor hump height. And the location of scoliosis apex and the number of curve are not influencing factors of self-image perception. Level IV, retrospective study. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

THE USE OF POLYMERS IN RADIOACTIVE WASTE PROCESSING SYSTEMS

Energy Technology Data Exchange (ETDEWEB)

Skidmore, E.; Fondeur, F.

2013-04-15

The Savannah River Site (SRS), one of the largest U.S. Department of Energy (DOE) sites, has operated since the early 1950s. The early mission of the site was to produce critical nuclear materials for national defense. Many facilities have been constructed at the SRS over the years to process, stabilize and/or store radioactive waste and related materials. The primary materials of construction used in such facilities are inorganic (metals, concrete), but polymeric materials are inevitably used in various applications. The effects of aging, radiation, chemicals, heat and other environmental variables must therefore be understood to maximize service life of polymeric components. In particular, the potential for dose rate effects and synergistic effects on polymeric materials in multivariable environments can complicate compatibility reviews and life predictions. The selection and performance of polymeric materials in radioactive waste processing systems at the SRS are discussed.

Software Configuration Management Plan for the Sodium Removal System

International Nuclear Information System (INIS)

HILL, L.F.

2000-01-01

This document establishers the Software Configuration Management Plan (SCMP) for the software associated with the control system of the Sodium Removal System (SRS) located in the Interim Examination and Maintenance (IEM Cell) Facility of the FFTF Flux Test

Optimizing Time Intervals of Meteorological Data Used with Atmospheric Dose Modeling at SRS

International Nuclear Information System (INIS)

Simpkins, A.A.

1999-01-01

Measured tritium oxide concentrations in air have been compared with calculated values using routine release Gaussian plume models for different time intervals of meteorological data. These comparisons determined an optimum time interval of meteorological data used with atmospheric dose models at the Savannah River Site (SRS). Meteorological data of varying time intervals (1-yr to 10-yr) were used for the comparison. Insignificant differences are seen in using a one-year database as opposed to a five-year database. Use of a ten-year database results in slightly more conservative results. For meteorological databases of length one to five years the mean ratio of predicted to measured tritium oxide concentrations is approximately 1.25 whereas for the ten-year meteorological database the ration is closer to 1.35. Currently at the Savannah River Site a meteorological database of five years duration is used for all dose models. This study suggests no substantially improved accuracy using meteorological files of shorter or longer time intervals

300 GPM Solids Removal System A True Replacement for Back Flushable Powdered Filter Systems - 13607

Energy Technology Data Exchange (ETDEWEB)

Ping, Mark R.; Lewis, Mark [EnergySolutions, Suite 100, Center Point II, 100 Center Point Circle, Columbia, SC 29210 (United States)

2013-07-01

The EnergySolutions Solids Removal System (SRS) utilizes stainless steel cross-flow ultra-filtration (XUF) technology which allows it to reliably remove suspended solids greater than one (1) micron from liquid radwaste streams. The SRS is designed as a pre-treatment step for solids separation prior to processing through other technologies such as Ion Exchange Resin (IER) and/or Reverse Osmosis (RO), etc. Utilizing this pre-treatment approach ensures successful production of reactor grade water while 1) decreasing the amount of radioactive water being discharged to the environment; and 2) decreasing the amount of radioactive waste that must ultimately be disposed of due to the elimination of spent powdered filter media. (authors)

300 GPM Solids Removal System A True Replacement for Back Flushable Powdered Filter Systems - 13607

International Nuclear Information System (INIS)

Ping, Mark R.; Lewis, Mark

2013-01-01

The EnergySolutions Solids Removal System (SRS) utilizes stainless steel cross-flow ultra-filtration (XUF) technology which allows it to reliably remove suspended solids greater than one (1) micron from liquid radwaste streams. The SRS is designed as a pre-treatment step for solids separation prior to processing through other technologies such as Ion Exchange Resin (IER) and/or Reverse Osmosis (RO), etc. Utilizing this pre-treatment approach ensures successful production of reactor grade water while 1) decreasing the amount of radioactive water being discharged to the environment; and 2) decreasing the amount of radioactive waste that must ultimately be disposed of due to the elimination of spent powdered filter media. (authors)

A comparison of the WIND System atmospheric models and RASCAL

International Nuclear Information System (INIS)

Fast, J.D.

1991-01-01

A detailed comparison of the characteristics of the WIND System atmospheric models and the NRC's RASCAL code was made. The modeling systems differ substantially in the way input is entered and the way output is displayed. Nevertheless, using the same source term and meteorological input parameters, the WIND System atmospheric models and RASCAL produce similar results in most situations. The WIND System atmospheric model predictions and those made by RASCAL are within a factor of two at least 70% of the time and are within a factor of four 89% of the time. Significant differences in the dose between the models may occur during conditions of low wind speeds, strong atmospheric stability, and/or wet deposition as well as for many atmospheric cases involving cloud shine. Even though the numerical results are similar in most cases, there are many site-specific and operational characteristics that have been incorporated into the WIND System atmospheric models to provide SRS emergency response personnel with a more effective emergency response tool than is currently available from using RASCAL

Introduction of means of electronic study in the system of the higher education

OpenAIRE

Andriy Marakushyn; Artem Cherednichenko

2015-01-01

Purpose: to estimate results of introduction of means of "electronic study" at physical training of students of Simon Kuznets Kharkiv national university of economics. Material and Methods: the research was conducted during 2013/14 in KhNUE among students of the first and second courses. In general for about 800 students took part in the research. Results: the system of the remote study (SRS) Chamilo is characterized; the algorithm of introduction of SRS Chamilo in physical training of studen...

The European Survey on Adverse Systemic Reactions in Allergen Immunotherapy (EASSI): A paediatric assessment.

Science.gov (United States)

Rodríguez Del Río, Pablo; Vidal, Carmen; Just, Jocelyne; Tabar, Ana I; Sanchez-Machin, Inmaculada; Eberle, Peter; Borja, Jesus; Bubel, Petra; Pfaar, Oliver; Demoly, Pascal; Calderón, Moises A

2017-02-01

Safety data on 'real-life' allergen immunotherapy (AIT) in children and adolescents is usually extrapolated from studies in adults. Patients aged 18 or under initiating aeroallergen AIT were evaluated in a prospective European survey. Patient profiles and systemic reactions (SRs) were recorded. Descriptive, univariate and multivariate analyses were used to identify risk factors for SRs. A total of 1563 patients (mean ± SD age: 11.7 ± 3.9 years; rhinitis: 93.7%; asthma: 61.5%; polysensitization: 62.5%) and 1578 courses of AIT were assessed. Single-allergen AIT was administered in 89.5% of cases (n = 1412; mites: 49%; grass pollen: 25.8%; tree pollen: 8.7%; Alternaria: 4.6%; dander: 0.8%; weed pollen: 0.6%). Subcutaneous AIT (SCIT) was used in 71.4% (n = 1127) of the treatments, including 574 (50.9%) with natural extracts. Sublingual AIT (SLIT) was used for the remaining 451 treatments (drops: 73.8%; tablets: 26.2%). The mean ± SD follow-up period was 12.9 ± 3.3 months. The estimated total number of doses was 19,669 for SCIT and 131,550 for SLIT. Twenty-four patients (1.53%) experienced 29 SRs. Respiratory (55.7%) and skin symptoms (37.9%) were most frequent. Anaphylaxis was diagnosed in 3 SRs (10.3%), and adrenaline was administered in 2 of these cases. In a univariate analysis, the risk of SRs was lower in mite-sensitized patients and higher in cases of pollen polysensitization (>3), grass pollen extracts and the use of natural extracts (vs. allergoids). In a real-life paediatric setting, AIT is safe. SRs are infrequent and generally not severe. Pollen polysensitization, grass pollen extracts and natural extracts (vs. allergoids) were risk factors for AIT-associated SRs. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Characterization of a signal recording system for accurate velocity estimation using a VISAR

Science.gov (United States)

Rav, Amit; Joshi, K. D.; Singh, Kulbhushan; Kaushik, T. C.

2018-02-01

The linearity of a signal recording system (SRS) in time as well as in amplitude are important for the accurate estimation of the free surface velocity history of a moving target during shock loading and unloading when measured using optical interferometers such as a velocity interferometer system for any reflector (VISAR). Signal recording being the first step in a long sequence of signal processes, the incorporation of errors due to nonlinearity, and low signal-to-noise ratio (SNR) affects the overall accuracy and precision of the estimation of velocity history. In shock experiments the small duration (a few µs) of loading/unloading, the reflectivity of moving target surface, and the properties of optical components, control the amount of input of light to the SRS of a VISAR and this in turn affects the linearity and SNR of the overall measurement. These factors make it essential to develop in situ procedures for (i) minimizing the effect of signal induced noise and (ii) determine the linear region of operation for the SRS. Here we report on a procedure for the optimization of SRS parameters such as photodetector gain, optical power, aperture etc, so as to achieve a linear region of operation with a high SNR. The linear region of operation so determined has been utilized successfully to estimate the temporal history of the free surface velocity of the moving target in shock experiments.

Safe management of spent radiation source

International Nuclear Information System (INIS)

Kosako, Toshiso; Sugiura, Nobuyuki; Valdezco, E.M.; Choi, Kwang-Sub

2003-01-01

Presented are 8 investigation reports concerning the safe management of spent radiation source (SRS) during the current 2 years. Four reports from Japan are: Scheme for SRS management (approach and present status of the SRS management and consideration toward solving problems); Current International Atomic Energy Agency (IAEA) activities related to safety of radiation sources (Chronology of action plan development, Outline of revised action plan, and Asian regional activities); Current status of SRS management in Japan (Regulation system, Obligations of licensed users, Regulatory system on sealed sources, Status in the incidents on sources occurred, Incident of source loss, and Incidents of orphan sources); and SRS management system in Japan (Current status of using of sealed sources, collection system of SRS-Japan Radioisotope Association (JRIA) services, and Disposal of SRS). Four reports from the Asian countries also concern the current statuses of SRS management in the Philippine (Radioactive waste sources, Waste management strategies, Conditioning of Ra sources, Ra project action plan, as low as reasonably achievable (ALARA) program, Dose assessment, Regulations on radioactive waste, Action plan on the safety and security of sources, IAEA Regional Demonstration Centers, and sitting studies for a near surface disposal facility); Thailand (Current status of using sealed sources, Inventory of SRS, and Current topics of SRS management); Indonesia (Principles of management of radiation sources, Legislative framework of SRS management practices, Regulatory on SRS, management of sealed SRS, management hurdles, and reported incidents); and Korea (Regulatory frame work, Collection systems of SRS, Radioisotope waste generation, Radiation exposure incident, and Scrap monitoring system). (N.I.)

Groundwater flow and tritium migration from the SRS Old Burial Ground to Fourmile Branch

International Nuclear Information System (INIS)

Flach, G.P.; Hamm, L.L.; Harris, M.K.

1996-04-01

The objectives of this investigation are twofold. The initial goal is to devise and demonstrate a technique for directly incorporating fine-scale lithologic data into heterogeneous hydraulic conductivity fields, for improved groundwater flow and contaminant transport model accuracy. The ultimate goal is to rigorously simulate past and future tritium migration from the SRS Old Burial Ground towards Fourmile Branch, to better understand the effects of various remediation alternatives such as no action and capping. Large-scale variability in hydraulic conductivity is usually the main influence on field-scale groundwater flow patterns and dispersive transport, following the relative locations of recharge and discharge areas. Incorporating realistic hydraulic conductivity heterogeneity into flow and transport models is paramount to accurate simulations, particularly for contaminant migration. Sediment lithologic descriptions and geophysical logs typically offer finer spatial resolution, and therefore more potential information about heterogeneity, than other site characterization data

Formal verification and validation of the safety-critical software in a digital reactor protection system

International Nuclear Information System (INIS)

Kwon, K. C.; Park, G. Y.

2006-01-01

This paper describes the Verification and Validation (V and V) activities for the safety-critical software in a Digital Reactor Protection System (DRPS) that is being developed through the Korea nuclear instrumentation and control system project. The main activities of the DRPS V and V process are a preparation of the software planning documentation, a verification of the software according to the software life cycle, a software safety analysis and a software configuration management. The verification works for the Software Requirement Specification (SRS) of the DRPS consist of a technical evaluation, a licensing suitability evaluation, a inspection and traceability analysis, a formal verification, and preparing a test plan and procedure. Especially, the SRS is specified by the formal specification method in the development phase, and the formal SRS is verified by a formal verification method. Through these activities, we believe we can achieve the functionality, performance, reliability, and safety that are the major V and V objectives of the nuclear safety-critical software in a DRPS. (authors)

Wind emergency response system

International Nuclear Information System (INIS)

Garrett, A.J.; Buckner, M.R.; Mueller, R.A.

1981-01-01

The WIND system is an automated emergency response system for real-time predictions of the consequences of liquid and airborne releases from SRP. The system consists of a minicomputer and associated peripherals necessary for acquisition and handling of large amounts of meteorological data from a local tower network and the National Weather Service. The minicomputer uses these data and several predictive models to assess the impact of accidental releases. The system is fast and easy to use, and output is displayed both in tabular form and as trajectory map plots for quick interpretation. The rapid response capabilities of the WIND system have been demonstrated in support of SRP operations

Reading and Cleaning out of Fault Codes in SRS%安全气囊（SRS）故障码的读取与清除

Institute of Scientific and Technical Information of China (English)

李涵武; 苏清源; 郭建华

2000-01-01

It takes the cases of General Motor Corporation, Ford Motor Company and TOYOTA Motor Corporation to introduce the ways of reading and cleaning out of fault codes in SRS.%介绍了通用公司、福特公司、丰田公司安全气囊故障码的读取与清除。

A Network Coverage Information-Based Sensor Registry System for IoT Environments.

Science.gov (United States)

Jung, Hyunjun; Jeong, Dongwon; Lee, Sukhoon; On, Byung-Won; Baik, Doo-Kwon

2016-07-25

The Internet of Things (IoT) is expected to provide better services through the interaction of physical objects via the Internet. However, its limitations cause an interoperability problem when the sensed data are exchanged between the sensor nodes in wireless sensor networks (WSNs), which constitute the core infrastructure of the IoT. To address this problem, a Sensor Registry System (SRS) is used. By using a SRS, the information of the heterogeneous sensed data remains pure. If users move along a road, their mobile devices predict their next positions and obtain the sensed data for that position from the SRS. If the WSNs in the location in which the users move are unstable, the sensed data will be lost. Consider a situation where the user passes through dangerous areas. If the user's mobile device cannot receive information, they cannot be warned about the dangerous situation. To avoid this, two novel SRSs that use network coverage information have been proposed: one uses OpenSignal and the other uses the probabilistic distribution of the users accessing SRS. The empirical study showed that the proposed method can seamlessly provide services related to sensing data under any abnormal circumstance.

A review of vapor explosion information pertinent to the SRS reactors

International Nuclear Information System (INIS)

Hyder, M.L.; Allison, D.K.

1992-04-01

Vapor explosions are explosive events resulting from the mixing of two liquids, one of which is heated to a temperature well above the boiling point of the second. Under some circumstances mixing of the liquids can boil part of the lower boiling liquid so quickly that the expanding vapor generates a strong pressure wave and explosion. If the lower boiling liquid is water, as is frequently the case, the event is called a ''steam explosion''. Analyses in support of the K-Reactor Probabilistic Risk Assessment have shown that steam explosions generated by the interaction of molten reactor fuel with water contribute significantly to the risk of reactor operation at the SRS. This calculated risk incorporates a conservative treatment of the uncertainties associated with such explosions. Study of steam explosions involving molten reactor materials has been included in the Severe Accident Analysis Program (SAAP) in order to obtain a better evaluation of their importance, and, if possible, to find ways to avoid them. This paper presents a brief review and summary of steam explosion experience from literature accounts, along with the results of experimental studies from the SAAP. It concludes with an evaluation of current knowledge, and suggestions for future development. 71 refs

Modeling Supermarket Refrigeration Systems for Supervisory Control in Smart Grid

DEFF Research Database (Denmark)

Shafiei, Seyed Ehsan; Rasmussen, Henrik; Stoustrup, Jakob

2013-01-01

A modular modeling approach of supermarket refrigeration systems (SRS) which is appropriate for smart grid control purposes is presented in this paper. Modeling and identification are performed by just knowing the system configuration and measured data disregarding the physical details. So...

DFT calculations of electronic and optical properties of SrS with LDA, GGA and mGGA functionals

Energy Technology Data Exchange (ETDEWEB)

Sharma, Shatendra, E-mail: shatendra@gmai.com [University Science Instrumentation Centre, Jawaharlal Nehru University, New Delhi-110067 (India); Sharma, Jyotsna [School of Basic & Applied Sciences, K. R. Mangalam University, Sohna Road, Gurgaon-122103 (India); Sharma, Yogita [Department of Applied Sciences, KIIT, Sohna Road, Gurgaon-122103 (India)

2016-05-06

The theoretical investigations of electronic and optical properties of SrS are made using the first principle DFT calculations. The calculations are performed for the local-density approximation (LDA), generalized gradient approximation (GGA) and for an alternative form of GGA i.e. metaGGA for both rock salt type (B1, Fm3m) and cesium chloride (B2, Pm3m) structures. The band structure, density of states and optical spectra are calculated under various available functional. The calculations with LDA and GGA functional underestimate the values of band gaps with all functional, however the values with mGGA show reasonably good agreement with experimental and those calculated by using other methods.

Business System Planning Project, Alternatives Analysis

International Nuclear Information System (INIS)

EVOSEVICH, S.

2000-01-01

The CHG Chief Information Officer (CIO) requested a study of alternatives to the current business system computing environment. This Business Systems Planning (BSP) Project Alternatives Analysis document presents an analysis of the current Project Controls, Work Management, and Business Management systems environment and alternative solutions that support the business functions. The project team has collected requirements and priorities from stakeholders in each business area and documented them in the BSP System Requirements Specification (SRS), RPP-6297. The alternatives analysis process identifies and measures possible solutions in each of the business process areas against the requirements as documented in the SRS. The team gathered input from both internal and external sources to identify and grade the possible solutions. This document captures the results of that activity and recommends a suite of software products. This study was to select the best product based on how well the product met the requirements, not to determine the platform or hardware environment that would be used. Additional analysis documentation can be found in BSP project files

The Sleeping Habits of Preschool Children Are Related to Temperament, Behavior, and Social Responsiveness

Directory of Open Access Journals (Sweden)

Seockhoon Chung

2013-06-01

Full Text Available Background and Objective Children’s sleep habits are important for their health and development. Here, we investigated the relationship between sleep habits, behavior, personality, and social responsiveness in children. Methods A total of 38 preschool children were assessed using the Korean Child Behavior Checklist (K-CBCL, Junior Temperament and Character Inventory (JTCI, Children’s Sleep Habit Questionnaire (CSHQ, and Social Responsiveness Scale (SRS. Results Harm avoidance according to JTCI was positively correlated with bedtime resistance (r = 0.34; p = 0.04 and sleep anxiety on the CSHQ (r = 0.43; p < 0.01. Emotional lability on the K-CBCL was significantly associated with parasomnias (r = 0.38; p = 0.02, while lower social cognition and social communication scores on the SRS were associated with sleep anxiety (r = −0.34; p = 0.03 and parasomnias (r = −0.38; p = 0.01. Path analysis showed that among the JTCI subscales, both harm avoidance and persistence were significantly associated with social cognition. Conclusions Clinicians should pay particular attention to psychological components as potential contributors to sleep habits when managing sleep problems in preschool children.

Assessing the Accuracy of the Modified Chinese Autism Spectrum Rating Scale and Social Responsiveness Scale for Screening Autism Spectrum Disorder in Chinese Children

Institute of Scientific and Technical Information of China (English)

Bingrui Zhou; Hao Zhou; Lijie Wu; Xiaobing Zou; Xuerong Luo; Eric Fombonne; Yi Wang; Weili Yan; Xiu Xu

2017-01-01

The reported prevalence of autism spectrum disorder (ASD) has been increasing rapidly in many parts of the world.However,data on its prevalence in China are largely missing.Here,we assessed the suitability of the modified Chinese version of a newly-developed ASD screening tool,the Modified Chinese Autism Spectrum Rating Scales (MC-ASRS) in screening for ASD in Chinese children aged 6-12 years,through comparison with the Social Responsiveness Scale (SRS) that has been widely used for ASD screening.We recruited the parents/caregivers of 1588 typically-developing children and 190 children with ASD aged 6-12 years to complete the MC-ASRS and SRS,and evaluated the validity of both scales in discriminating children with ASD from those developing typically.The results showed that MC-ASRS performed as well as SRS in sensitivity,specificity,and area-under-the-curve (both ＞0.95) in receiver operating characteristic analysis,with a fair false-negative rate.These results suggest that MC-ASRS is a promising tool for screening for children with ASD in the general Chinese population.

Implementation of the Timepix ASIC in the Scalable Readout System

Energy Technology Data Exchange (ETDEWEB)

Lupberger, M., E-mail: lupberger@physik.uni-bonn.de; Desch, K.; Kaminski, J.

2016-09-11

We report on the development of electronics hardware, FPGA firmware and software to provide a flexible multi-chip readout of the Timepix ASIC within the framework of the Scalable Readout System (SRS). The system features FPGA-based zero-suppression and the possibility to read out up to 4×8 chips with a single Front End Concentrator (FEC). By operating several FECs in parallel, in principle an arbitrary number of chips can be read out, exploiting the scaling features of SRS. Specifically, we tested the system with a setup consisting of 160 Timepix ASICs, operated as GridPix devices in a large TPC field cage in a 1 T magnetic field at a DESY test beam facility providing an electron beam of up to 6 GeV. We discuss the design choices, the dedicated hardware components, the FPGA firmware as well as the performance of the system in the test beam.

SAVANNAH RIVER SITE CAPABILITIES FOR CONDUCTING INGESTION PATHWAY CONSEQUENCE ASSESSMENTS FOR EMERGENCY RESPONSE

Energy Technology Data Exchange (ETDEWEB)

Hunter, C

2007-12-11

Potential airborne releases of radioactivity from facilities operated for the U. S. Department of Energy at the Savannah River Site could pose significant consequences to the public through the ingestion pathway. The Savannah River National Laboratory has developed a suite of technologies needed to conduct assessments of ingestion dose during emergency response, enabling emergency manager at SRS to develop initial protective action recommendation for state agencies early in the response and to make informed decisions on activation of additional Federal assets that would be needed to support long-term monitoring and assessment activities.

Demonstration of a utility industry horizontal drilling system: Horizontal well AMH-5 installation report

International Nuclear Information System (INIS)

1992-01-01

The Department of Energy's Office of Technology Development initiated an integrated demonstration of innovative technologies and systems for cleanup of VOCs in soils and groundwater at the Savannah River Site (SRS) in 1989. The overall goal of the program is demonstration of multiple technologies and systems in the fields of drilling, characterization, monitoring, and remediation at a single test bed. Innovative technologies are compared to one another and to baseline technologies in terms of technical performance and cost effectiveness. Transfer of successfully demonstrated technologies and systems to DOE environmental restoration organizations, to other government agencies, and to industry is a critical part of the program. Directional drilling has been shown to be a successful technique for enhancing access to the subsurface, thus improving remediation systems, especially remediation systems which perform in situ. Demonstration of an innovative directional drilling system at the Integrated Demonstration Site at the SRS, was initiated in June of 1992. The directional drilling system was designed to install an in situ remediation system. The drilling system is an experimental compaction/dry drilling technique developed by Charles Machine Works (Ditch Witch reg-sign) of Perry, Oklahoma. A horizontal well was installed in the M Area of the SRS below and parallel to an abandoned tile process sewer line. The installation of the horizontal well was a two-part process. Part one consisted of drilling the borehole, and part two was the horizontal well completion

Solid Waste Information and Tracking System (SWITS) Software Requirements Specification

International Nuclear Information System (INIS)

MAY, D.L.

2000-01-01

This document is the primary document establishing requirements for the Solid Waste Information and Tracking System (SWITS) as it is converted to a client-server architecture. The purpose is to provide the customer and the performing organizations with the requirements for the SWITS in the new environment. This Software Requirement Specification (SRS) describes the system requirements for the SWITS Project, and follows the PHMC Engineering Requirements, HNF-PRO-1819, and Computer Software Qualify Assurance Requirements, HNF-PRO-309, policies. This SRS includes sections on general description, specific requirements, references, appendices, and index. The SWITS system defined in this document stores information about the solid waste inventory on the Hanford site. Waste is tracked as it is generated, analyzed, shipped, stored, and treated. In addition to inventory reports a number of reports for regulatory agencies are produced

Solid Waste Information and Tracking System (SWITS) Software Requirements Specification

Energy Technology Data Exchange (ETDEWEB)

MAY, D.L.

2000-03-22

This document is the primary document establishing requirements for the Solid Waste Information and Tracking System (SWITS) as it is converted to a client-server architecture. The purpose is to provide the customer and the performing organizations with the requirements for the SWITS in the new environment. This Software Requirement Specification (SRS) describes the system requirements for the SWITS Project, and follows the PHMC Engineering Requirements, HNF-PRO-1819, and Computer Software Qualify Assurance Requirements, HNF-PRO-309, policies. This SRS includes sections on general description, specific requirements, references, appendices, and index. The SWITS system defined in this document stores information about the solid waste inventory on the Hanford site. Waste is tracked as it is generated, analyzed, shipped, stored, and treated. In addition to inventory reports a number of reports for regulatory agencies are produced.

Bioremediation of mixed microbial mats: System development of mixed contaminants for application at the Savannah River Site. Annual technical progress report, October 1, 1995--September 30, 1996

International Nuclear Information System (INIS)

Bender, J.; Phillips, P.

1996-01-01

The fundamental objective of this project is to develop and field test the mixed microbial mat bioremediation system for decontamination of target sites at SRS. Although microbial mats have performed well in several pilot projects in the past, atypical problems and site characteristics at SRS demand special field designs. In the interest of designing a pilot and locating it at an appropriate site, the project investigators have worked closely with the technical staff at the SREL. We have concluded that the diverse characteristics of contaminations at SRS may dictate testing several pilot designs during the course of this project

Formal verification method for nuclear I and C systems using ESDT and SMV in the software design phase

International Nuclear Information System (INIS)

Song, Myung Jun; Koo, Seo Ryong; Seong, Poong Hyun

2004-01-01

As PLCs are widely used in the digital I and C systems of nuclear power plants (NPPs), the safety of PLC software has become the most important consideration. Software safety is an important property for safety critical systems, especially those in aerospace, satellite and nuclear power plants, whose failure could result in danger to human life, property or environment. It is recently becoming more important due to the increase in the complexity and size of safety critical systems. This research proposes a method to perform effective verification tasks on the traceability analysis and software design evaluation in the software design phase. In order to perform the traceability analysis between a Software Requirements Specification (SRS) written in a natural language and a Software Design Specification (SDS) written in Function Block Diagram (FBD), this method uses extended-structured decision tables (ESDTs). ESDTs include information related to the traceability analysis from a text-based SRS and a FBD-based SDS, respectively. Through comparing with both ESDTs from an SRS and ESDTs from an SDS, the effective traceability analysis of both a text-based SRS and a FBD-based SDS can be achieved. For the software design evaluation, a model checking, which is mainly used to verify PLC programs formally, is used in this research. A FBD-style design specification is translated into input languages of the SMV by translation rules and then the FBD-style design specification can be formally analyzed using SMV. (author)

Empirical Model Development for Predicting Shock Response on Composite Materials Subjected to Pyroshock Loading

Science.gov (United States)

Gentz, Steven J.; Ordway, David O; Parsons, David S.; Garrison, Craig M.; Rodgers, C. Steven; Collins, Brian W.

2015-01-01

The NASA Engineering and Safety Center (NESC) received a request to develop an analysis model based on both frequency response and wave propagation analyses for predicting shock response spectrum (SRS) on composite materials subjected to pyroshock loading. The model would account for near-field environment (approx. 9 inches from the source) dominated by direct wave propagation, mid-field environment (approx. 2 feet from the source) characterized by wave propagation and structural resonances, and far-field environment dominated by lower frequency bending waves in the structure. This report documents the outcome of the assessment.

Simulation of Seismic Response of Reinforced Concrete Beam-Column Joints with Nurbs Surface Fitting

Directory of Open Access Journals (Sweden)

Mirhosseini R. Tabatabaei

2017-09-01

Full Text Available This paper presents an approach based on NURBS (non-uniform rational B-splines to achieve a seismic response surface (SRS from a group of points obtained by using an analytical model of RC joints. NURBS based on the genetic algorithm is an important mathematical tool and consists of generalizations of Bezier curves and surfaces and B-splines. Generally, the accuracy of the design process of joints depends on the number of control points that are captured in the results of experimental research on real specimens. The values obtained from the specimens are the best tools to use in seismic analysis, though more expensive when compared to values simulated by SRSs. The SRS proposed in this paper can be applied to obtain surfaces that show site effect results on destructions of beam-column joint, taking into account different site conditions for a specific earthquake. The efficiency of this approach is demonstrated by the retrieval of simulated-versus-analytical results.

Acceptance of a systematic review as a thesis: survey of biomedical doctoral programs in Europe.

Science.gov (United States)

Puljak, Livia; Sapunar, Damir

2017-12-12

Systematic reviews (SRs) have been proposed as a type of research methodology that should be acceptable for a graduate research thesis. The aim of this study was to analyse whether PhD theses in European biomedical graduate programs can be partly or entirely based on SRs. In 2016, we surveyed individuals in charge of European PhD programs from 105 institutions. The survey asked about acceptance of SRs as the partial or entire basis for a PhD thesis, their attitude towards such a model for PhD theses, and their knowledge about SR methodology. We received responses from 86 individuals running PhD programs in 68 institutions (institutional response rate of 65%). In 47% of the programs, SRs were an acceptable study design for a PhD thesis. However, only 20% of participants expressed a personal opinion that SRs meet the criteria for a PhD thesis. The most common reasons for not accepting SRs as the basis for PhD theses were that SRs are 'not a result of a PhD candidate's independent work, but more of a team effort' and that SRs 'do not produce enough new knowledge for a dissertation'. The majority of participants were not familiar with basic concepts related to SRs; questions about meta-analyses and the type of plots frequently used in SRs were correctly answered by only one third of the participants. Raising awareness about the importance of SRs and their methodology could contribute to higher acceptance of SRs as a type of research that forms the basis of a PhD thesis.

A comparison of three methods for determining the amount of nitric acid needed to treat HLW sludge at SRS

International Nuclear Information System (INIS)

Siegwald, S.F.; Ferrara, D.M.

1994-01-01

A comparison was made of three methods for determining the amount of nitric acid which will be needed to treat a sample of high-level waste (HLW) sludge from the Savannah River Site (SRS) Tank Farm. The treatment must ensure the resulting melter feed will have the necessary rheological and oxidation-reduction properties, reduce mercury and manganese in the sludge, and be performed in a fashion which does not produce a flammable gas mixture. The three methods examined where an empirical method based on pH measurements, a computational method based on known reactions of the species in the sludge and a titration based on neutralization of carbonate in the solution

The Brazilian emergency response system

International Nuclear Information System (INIS)

Santos, Raul dos

1997-01-01

With the objective of improving the response actions to potential or real emergency situations generated by radiological or nuclear accidents, the Brazilian National Nuclear Energy Commission (CNEN) installed an integrated response system on a 24 hours basis. All the natiowide notifications on events that may start an emergency situation are converged to this system. Established since July 1990, this system has received around 300 notifications in which 5% were classified as potential emergency situation. (author)

Autonomous Sampling Platform Development: Radiological Contamination Mapping at SRS

International Nuclear Information System (INIS)

Moya, Nicholas; Whiteside, Tad

2016-01-01

From 1961 to 1964, radioactive elements were released from the Savannah River Site into local bodies of water via cooling water charges from the reactors on site. In 1983, the extent of the radioactive contamination was first studied, and elements such as 137 Cs, 90 Sr, 238 Pu, 241 Am, 244 Cm, and tritium were found to have seeped from local bodies of water into sediment and the surrounding flora and fauna. The current method of tracking and monitoring radioactive contamination at the SRS is to gather samples and conduct measurements in a laboratory. A cheaper, and safer, method to conduct such measurements would be to automate the process by using an autonomous boat that can travel to locations, conduct measurements, and return home all without human intervention. To introduce this idea, the construction of an autonomous boat prototype was completed to demonstrate the practicality and feasibility of such an idea. The prototype travels to a set of waypoints, stops at each waypoint, and returns when all waypoints have been reached. It does this by employing a simple battery-powered boat with an Arduino controller that steers the boat using a steering algorithm incorporated into a Proportional Integral Derivative (PID) function. A total of three tests were conducted at two different bodies of water; and after working out some hardware problems, the boat drone was able to successfully steer and reach all programmed waypoints. With the prototype complete, the next steps to realizing the final product of the boat drone will include adopting a processing unit with higher-bit architecture, using a bigger boat with a more powerful trolling motor, and incorporating a solar panel for continuous power and round-the-clock performance.

Autonomous Sampling Platform Development: Radiological Contamination Mapping at SRS

Energy Technology Data Exchange (ETDEWEB)

Moya, Nicholas [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Whiteside, Tad [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2016-07-01

From 1961 to 1964, radioactive elements were released from the Savannah River Site into local bodies of water via cooling water charges from the reactors on site. In 1983, the extent of the radioactive contamination was first studied, and elements such as ¹³⁷Cs, ⁹⁰Sr, ²³⁸Pu, ²⁴¹Am, ²⁴⁴Cm, and tritium were found to have seeped from local bodies of water into sediment and the surrounding flora and fauna. The current method of tracking and monitoring radioactive contamination at the SRS is to gather samples and conduct measurements in a laboratory. A cheaper, and safer, method to conduct such measurements would be to automate the process by using an autonomous boat that can travel to locations, conduct measurements, and return home all without human intervention. To introduce this idea, the construction of an autonomous boat prototype was completed to demonstrate the practicality and feasibility of such an idea. The prototype travels to a set of waypoints, stops at each waypoint, and returns when all waypoints have been reached. It does this by employing a simple battery-powered boat with an Arduino controller that steers the boat using a steering algorithm incorporated into a Proportional Integral Derivative (PID) function. A total of three tests were conducted at two different bodies of water; and after working out some hardware problems, the boat drone was able to successfully steer and reach all programmed waypoints. With the prototype complete, the next steps to realizing the final product of the boat drone will include adopting a processing unit with higher-bit architecture, using a bigger boat with a more powerful trolling motor, and incorporating a solar panel for continuous power and round-the-clock performance.

Health protection at the Savannah River Site: A guide to records series of the Department of Energy and its contractors

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-09-01

As part of the Department of Energy`s (DOE) Epidemiologic Records Inventory Project, History Associates Incorporated (HAI) prepared this guide to the records series pertaining to health protection activities at the DOE`s Savannah River Site (SRS). Since its inception in the early 1950s, the SRS, formerly known as the Savannah River Plant (SRP), has demonstrated significant interest in safeguarding facilities, protecting employees` health, and monitoring the environment. The guide describes records that concern health protection program administration, radiological monitoring of the plant and the environment, calibration and maintenance of monitoring instruments, internal and external dosimetry practices, medical surveillance of employees, occupational safety and training measures, site visitation, and electronic information systems. The introduction to the guide describes the Epidemiologic Records Inventory Project and HAI`s role in the project. It provides brief histories of the DOE, SRS, and the SRS organizational units responsible for health protection activities. This introduction also summarizes HAI`s methodology in developing criteria and conducting its verification of the SRS inventory of active and inactive SRS Health Protection records. Furthermore, it furnishes information on the production of the guide, the content of the records series descriptions, the location of the records, and the procedures for accessing records repositories.

Health protection at the Savannah River Site: A guide to records series of the Department of Energy and its contractors

International Nuclear Information System (INIS)

1996-09-01

As part of the Department of Energy's (DOE) Epidemiologic Records Inventory Project, History Associates Incorporated (HAI) prepared this guide to the records series pertaining to health protection activities at the DOE's Savannah River Site (SRS). Since its inception in the early 1950s, the SRS, formerly known as the Savannah River Plant (SRP), has demonstrated significant interest in safeguarding facilities, protecting employees' health, and monitoring the environment. The guide describes records that concern health protection program administration, radiological monitoring of the plant and the environment, calibration and maintenance of monitoring instruments, internal and external dosimetry practices, medical surveillance of employees, occupational safety and training measures, site visitation, and electronic information systems. The introduction to the guide describes the Epidemiologic Records Inventory Project and HAI's role in the project. It provides brief histories of the DOE, SRS, and the SRS organizational units responsible for health protection activities. This introduction also summarizes HAI's methodology in developing criteria and conducting its verification of the SRS inventory of active and inactive SRS Health Protection records. Furthermore, it furnishes information on the production of the guide, the content of the records series descriptions, the location of the records, and the procedures for accessing records repositories

A Systematic Review of Group Social Skills Interventions, and Meta-analysis of Outcomes, for Children with High Functioning ASD.

Science.gov (United States)

Wolstencroft, J; Robinson, L; Srinivasan, R; Kerry, E; Mandy, W; Skuse, D

2018-07-01

Group social skills interventions (GSSIs) are a commonly offered treatment for children with high functioning ASD. We critically evaluated GSSI randomised controlled trials for those aged 6-25 years. Our meta-analysis of outcomes emphasised internal validity, thus was restricted to trials that used the parent-report social responsiveness scale (SRS) or the social skills rating system (SSRS). Large positive effect sizes were found for the SRS total score, plus the social communication and restricted interests and repetitive behaviours subscales. The SSRS social skills subscale improved with moderate effect size. Moderator analysis of the SRS showed that GSSIs that include parent-groups, and are of greater duration or intensity, obtained larger effect sizes. We recommend future trials distinguish gains in children's social knowledge from social performance.

Lighting Systems Control for Demand Response

NARCIS (Netherlands)

Husen, S.A.; Pandharipande, A.; Tolhuizen, L.M.G.; Wang, Y.; Zhao, M.

2012-01-01

Lighting is a major part of energy consumption in buildings. Lighting systems will thus be one of the important component systems of a smart grid for dynamic load management services like demand response.In the scenario considered in this paper, under a demand response request, lighting systems in a

INTER- AND INTRAFRACTION MOTION FOR STEREOTACTIC RADIOSURGERY IN DOGS AND CATS USING A MODIFIED BRAINLAB FRAMELESS STEREOTACTIC MASK SYSTEM.

Science.gov (United States)

Dieterich, Sonja; Zwingenberger, Allison; Hansen, Katherine; Pfeiffer, Isabella; Théon, Alain; Kent, Michael S

2015-01-01

Precise and accurate patient positioning is necessary when doing stereotactic radiosurgery (SRS) to ensure adequate dosing to the tumor and sparing of normal tissues. This prospective cross-sectional study aimed to assess feasibility of a commercially available modified frameless SRS positioning system for use in veterinary radiotherapy patients with brain tumors. Fifty-one dogs and 12 cats were enrolled. Baseline and verification CT images were acquired. The verification CT images from 32 dogs and five cats had sufficient images for fusion to baseline CT images. A rigid box-based fusion was performed to determine interfraction motion. Forty-eight dogs and 11 cats were assessed for intrafraction motion by cine CT. Seventy percent of dogs and 60% of cats had interfraction 3D vector translational shifts >1 mm, with mean values of 1.9 mm in dogs, and 1.8 mm in cats. In dogs muscle wasting was weakly correlated with translational shifts. The maximum angular interfraction motion observed was 6.3° (roll), 3.5° (pitch), and 3.3° (yaw). There was no correlation between angular interfraction motion and weight, brachycephaly, or muscle wasting. Fifty-seven percent of dogs and 50% of cats had respiration-related intrafraction motion. Of these, 4.5% of dogs and 10% of cats had intrafraction motion >1 mm. This study demonstrates the modified Brainlab system is feasible for SRS in dogs and cats. The smaller cranial size and difference in anatomy increases setup uncertainty in some animals beyond limits usually accepted in SRS. Image-guided positioning is recommended to achieve clinically acceptable setup accuracy (<1 mm) for SRS. © 2015 American College of Veterinary Radiology.

SU-E-T-751: Three-Component Kinetic Model of Tumor Growth and Radiation Response for Stereotactic Radiosurgery

Energy Technology Data Exchange (ETDEWEB)

Watanabe, Y; Dahlman, E; Leder, K; Hui, S [University of Minnesota, Minneapolis, MN (United States)

2015-06-15

Purpose: To develop and study a kinetic model of tumor growth and its response to stereotactic radiosurgery (SRS) by assuming that the cells in irradiated tumor volume were made of three types. Methods: A set of ordinary differential equations (ODEs) were derived for three types of cells and a tumor growth rate. It is assumed that the cells were composed of actively proliferating cells, lethally damaged-dividing cells, and non-dividing cells. We modeled the tumor volume growth with a time-dependent growth rate to simulate the saturation of growth. After SRS, the proliferating cells were permanently damaged and converted to the lethally damaged cells. The amount of damaged cells were estimated by the LQ-model. The damaged cells gradually stopped dividing/proliferating and died with a constant rate. The dead cells were cleared from their original location with a constant rate. The total tumor volume was the sum of the three components. The ODEs were numerically solved with appropriate initial conditions for a given dosage. The proposed model was used to model an animal experiment, for which the temporal change of a rhabdomyosarcoma tumor volume grown in a rat was measured with time resolution sufficient to test the model. Results: To fit the model to the experimental data, the following characteristics were needed with the model parameters. The α-value in the LQ-model was smaller than the commonly used value; furthermore, it decreased with increasing dose. At the same time, the tumor growth rate after SRS had to increase. Conclusions: The new 3-component model of tumor could simulate the experimental data very well. The current study suggested that the radiation sensitivity and the growth rate of the proliferating tumor cells may change after irradiation and it depended on the dosage used for SRS. These preliminary observations must be confirmed by future animal experiments.

REVIEW OF ALTERNATIVE ENHANCED CHEMICAL CLEANING OPTIONS FOR SRS WASTE TANKS

Energy Technology Data Exchange (ETDEWEB)

Hay, M.; Koopman, D.

2009-08-01

A literature review was conducted to support the Task Technical and Quality Assurance Plan for Alternative Enhanced Chemical Cleaning (AECC) for sludge heel removal funded as part of the EM-21 Engineering and Technology program. The goal was to identify potential technologies or enhancements to the baseline oxalic acid cleaning process for chemically dissolving or mobilizing Savannah River Site (SRS) sludge heels. The issues with the potentially large volume of oxalate solids generated from the baseline process have driven an effort to find an improved or enhanced chemical cleaning technology for the tank heels. This literature review builds on a previous review conducted in 2003. A team was charged with evaluating the information in these reviews and developing recommendations of alternative technologies to pursue. The new information in this report supports the conclusion of the previous review that oxalic acid remains the chemical cleaning agent of choice for dissolving the metal oxides and hydroxides found in sludge heels in carbon steel tanks. The potential negative impact of large volumes of sodium oxalate on downstream processes indicates that the amount of oxalic acid used for chemical cleaning needs to be minimized as much as possible or the oxalic acid must be destroyed prior to pH adjustment in the receipt tank. The most straightforward way of minimizing the volume of oxalic acid needed for chemical cleaning is through more effective mechanical cleaning. Using a mineral acid to adjust the pH of the sludge prior to adding oxalic acid may also help to minimize the volume of oxalic acid used in chemical cleaning. If minimization of oxalic acid proves insufficient in reducing the volume of oxalate salts, several methods were found that could be used for oxalic acid destruction. For some waste tank heels, another acid or even caustic treatment (or pretreatment) might be more appropriate than the baseline oxalic acid cleaning process. Caustic treatment of high

Development of the safety PLC for plant protection system

Energy Technology Data Exchange (ETDEWEB)

Kim, Chang Hwoi; Lee, Dong Young [Korea Atomic Energy Research Institute, Taejeon (Korea, Republic of)

2005-11-15

The safety PLC (POSAFE-Q) is developing in the Korea Nuclear Instrumentation and Control System (KNICS) R and D project. The PLC satisfies Safety Class 1E, Quality Class 1, and Seismic Category I. The software such as RTOS and firmware are developed according to safety critical software life cycle. Especially, the formal method is applied to design SRS (Software Requirement Spec.) and SDS (Software Design Specification.) for error-free. The developed software according to software life cycle is verified by independent software V and V team. The overall response time from an input to the outputs shall be 50ms or less. The prototype for the POSAFE-Q was developed and functional testing and equipment qualification tests have been underway.

Stereotactic treatment. Definitions and literature overview

International Nuclear Information System (INIS)

Fontenla, D.P.

2008-01-01

The topics discussed include, among others, the following: Radiosurgery definitions; Stereotactic radiosurgery (SRS) and stereotactic radiotherapy (SRT); Available uncertainties in SRS; Gamma knife; Linac-based SRS; Components of a radiosurgery system; Stereotactic hardware (brain lab); m3 linac attachment; Radiosurgery - clinical procedure; Cancer management; Rationale for SRT; Role of radiosurgery in the management of intracranial tumors; Indications for stereotactic SRS/SRT; Physical components required for SRS/SRT; Stereotactic patient set-up; Stereotactic CT scan for SRS; Physical components required for SRT: Relocatable head frame (GTC); Patient immobilization; Treatment planning system; Basic requirements for SRS dosimetry (Linac based); Stereotactic set-up QA (Linac); Stereotactic frames and QA; Beam dose measurements; Dose evaluation tools; Phantoms. (P.A.)

Voice Response Systems Technology.

Science.gov (United States)

Gerald, Jeanette

1984-01-01

Examines two methods of generating synthetic speech in voice response systems, which allow computers to communicate in human terms (speech), using human interface devices (ears): phoneme and reconstructed voice systems. Considerations prior to implementation, current and potential applications, glossary, directory, and introduction to Input Output…

Can Autism Spectrum Disorders and Social Anxiety Disorders Be Differentiated by the Social Responsiveness Scale in Children and Adolescents?

Science.gov (United States)

Cholemkery, Hannah; Mojica, Laura; Rohrmann, Sonja; Gensthaler, Angelika; Freitag, Christine M.

2014-01-01

Autism spectrum disorder (ASD) as well as social phobia (SP), and selective mutism (SM) are characterised by impaired social interaction. We assessed the validity of the Social Responsiveness Scale (SRS) to differentiate between ASD, and SP/SM. Raw scores were compared in 6-18 year old individuals with ASD (N = 60), SP (N = 38), SM (N = 43), and…

Stereotactic Image-Guided Intensity Modulated Radiotherapy Using the HI-ART II Helical Tomotherapy System

International Nuclear Information System (INIS)

Holmes, Timothy W.; Hudes, Richard; Dziuba, Sylwester; Kazi, Abdul; Hall, Mark; Dawson, Dana

2008-01-01

The highly integrated adaptive radiation therapy (HI-ART II) helical tomotherapy unit is a new radiotherapy machine designed to achieve highly precise and accurate treatments at all body sites. The precision and accuracy of the HI-ART II is similar to that provided by stereotactic radiosurgery systems, hence the historical distinction between external beam radiotherapy and stereotactic procedures based on differing precision requirements is removed for this device. The objectives of this work are: (1) to describe stereotactic helical tomotherapy processes (SRS, SBRT); (2) to show that the precision and accuracy of the HI-ART meet the requirements defined for SRS and SBRT; and (3) to describe the clinical implementation of a stereotactic image-guided intensity modulated radiation therapy (IG-IMRT) system that incorporates optical motion management

Automated spike preparation system for Isotope Dilution Mass Spectrometry (IDMS)

International Nuclear Information System (INIS)

Maxwell, S.L. III; Clark, J.P.

1990-01-01

Isotope Dilution Mass Spectrometry (IDMS) is a method frequently employed to measure dissolved, irradiated nuclear materials. A known quantity of a unique isotope of the element to be measured (referred to as the ''spike'') is added to the solution containing the analyte. The resulting solution is chemically purified then analyzed by mass spectrometry. By measuring the magnitude of the response for each isotope and the response for the ''unique spike'' then relating this to the known quantity of the ''spike'', the quantity of the nuclear material can be determined. An automated spike preparation system was developed at the Savannah River Site (SRS) to dispense spikes for use in IDMS analytical methods. Prior to this development, technicians weighed each individual spike manually to achieve the accuracy required. This procedure was time-consuming and subjected the master stock solution to evaporation. The new system employs a high precision SMI Model 300 Unipump dispenser interfaced with an electronic balance and a portable Epson HX-20 notebook computer to automate spike preparation

Acceptance test procedure for the master equipment list (MEL)database system -- phase I

International Nuclear Information System (INIS)

Jech, J.B.

1997-01-01

The Waste Remediation System/.../Facilities Configuration Management Integration group has requested development of a system to help resolve many of the difficulties associated with management of master equipment list information. This project has been identified as Master Equipment List (MEL) database system. Further definition is contained in the system requirements specification (SRS), reference 7

Linac based radiosurgery and stereotactic radiotherapy

International Nuclear Information System (INIS)

Mackie, T.R.

2008-01-01

The following topics were discussed: Definition of stereotactic radiosurgery (SRS) and stereotactic radiotherapy (SRT); Stereo market; Indications for SRS/SRT; History of linac-based SRS/SRT; Variety of systems; QA for SRS; Localization; and Imaging. (P.A.)

Fractionated stereotactic radiosurgery for patients with skull base metastases from systemic cancer involving the anterior visual pathway

International Nuclear Information System (INIS)

Minniti, Giuseppe; Osti, Mattia Falchetto; Maurizi Enrici, Riccardo; Esposito, Vincenzo; Clarke, Enrico; Scaringi, Claudia; Bozzao, Alessandro; Falco, Teresa; De Sanctis, Vitaliana; Enrici, Maurizio Maurizi; Valeriani, Maurizio

2014-01-01

To analyze the tumor control, survival outcomes, and toxicity after stereotactic radiosurgery (SRS) for skull base metastases from systemic cancer involving the anterior visual pathway. We have analyzed 34 patients (23 females and 11 males, median age 59 years) who underwent multi-fraction SRS for a skull base metastasis compressing or in close proximity of optic nerves and chiasm. All metastases were treated with frameless LINAC-based multi-fraction SRS in 5 daily fractions of 5 Gy each. Local control, distant failure, and overall survival were estimated using the Kaplan-Meier method calculated from the time of SRS. Prognostic variables were assessed using log-rank and Cox regression analyses. At a median follow-up of 13 months (range, 2–36.5 months), twenty-five patients had died and 9 were alive. The 1-year and 2-year local control rates were 89% and 72%, and respective actuarial survival rates were 63% and 30%. Four patients recurred with a median time to progression of 12 months (range, 6–27 months), and 17 patients had new brain metastases at distant brain sites. The 1-year and 2-year distant failure rates were 50% and 77%, respectively. On multivariate analysis, a Karnofsky performance status (KPS) >70 and the absence of extracranial metastases were prognostic factors associated with lower distant failure rates and longer survival. After multi-fraction SRS, 15 (51%) out of 29 patients had a clinical improvement of their preexisting cranial deficits. No patients developed radiation-induced optic neuropathy during the follow-up. Multi-fraction SRS (5 x 5 Gy) is a safe treatment option associated with good local control and improved cranial nerve symptoms for patients with a skull base metastasis involving the anterior visual pathway

Probabilistic risk assessment support of emergency preparedness at the Savannah River Site

International Nuclear Information System (INIS)

O'Kula, K.R.; Baker, W.H.; Simpkins, A.A.; Taylor, R.P.; Wagner, K.C.; Amos, C.N.

1992-01-01

Integration of the Probabilistic Risk Assessment (PRA) for K Reactor operation into related technical areas at the Savannah River Site (SRS) includes coordination with several onsite organizations responsible for maintaining and upgrading emergency preparedness capabilities. Major functional categories of the PRA application are scenario development and source term algorithm enhancement. Insights and technologies from the SRS PRA have facilitated development of: (1) credible timelines for scenarios; (2) algorithms tied to plant instrumentation to provide best-estimate source terms for dose projection; and (3) expert-system logic models to implement informed counter-measures to assure onsite and offsite safety following accidental releases. The latter methodology, in particular, is readily transferable to other reactor and non-reactor facilities at SRS and represents a distinct advance relative to emergency preparedness capabilities elsewhere in the DOE complex

The systemic inflammatory response syndrome.

Science.gov (United States)

Robertson, Charles M; Coopersmith, Craig M

2006-04-01

The systemic inflammatory response syndrome (SIRS) is the body's response to an infectious or noninfectious insult. Although the definition of SIRS refers to it as an "inflammatory" response, it actually has pro- and anti-inflammatory components. This review outlines the pathophysiology of SIRS and highlights potential targets for future therapeutic intervention in patients with this complex entity.

Determinants of the response of left ventricular ejection fraction to vasodilator stress in electrocardiographically gated {sup 82}rubidium myocardial perfusion PET

Energy Technology Data Exchange (ETDEWEB)

Brown, Tracy L.Y.; Merrill, Jennifer; Bengel, Frank M. [Johns Hopkins University, Department of Radiology and Radiological Sciences, Division of Nuclear Medicine, Baltimore, MD (United States); Volokh, Lana [GE Healthcare, Haifa (Israel)

2008-02-15

Myocardial perfusion imaging with {sup 82}Rb PET allows for ECG-gated studies to be obtained early after radiotracer injection, capturing ventricular function close to peak pharmacologic action of dipyridamole. This is different from gated SPECT and may potentially provide additional diagnostic information. We sought to identify potential correlates of the PET-derived ejection fraction response to vasodilator stress. One hundred ten consecutive patients undergoing {sup 82}Rb PET myocardial perfusion imaging during evaluation for coronary artery disease were included. Using a GE Discovery STRx PET-CT scanner, ECG-gated images (eight bins) were obtained at rest and 4 min after dipyridamole infusion, 90 s after infusion of 1,480-2,220 MBq of {sup 82}Rb. Summed rest, stress, and difference scores (SRS, SSS, and SDS) were determined using a five-point scoring system and 20-segment model. Ejection fraction was calculated using automated QGS software. Significant reversibility (SDS {>=} 4) was found in 23 patients (21%). Mean LVEF in all patients was 47 {+-} 13% at rest and 53 {+-} 13% during dipyridamole. LVEF increased in 89 patients, and decreased in 17 patients during vasodilation. The change in LVEF was inversely correlated with SDS (r = -0.26; p = 0.007). Additionally, it was inversely correlated with resting LVEF (r = -0.20; p = 0.03) and SSS (r = -0.25; p = 0.009). No significant correlations were observed with SRS, heart rate, blood pressure, age, hypertension, hypercholesterolemia, or pretest likelihood of disease. At multivariate regression analysis, SDS was an independent predictor of the change in LVEF. Gated {sup 82}Rb PET during pharmacologic stress allows for assessment of the functional response to vasodilation. The magnitude of LVEF increase is determined by stress perfusion/reversible perfusion defects. Functional response to hyperemia may thus be incorporated in future evaluations of diagnostic and prognostic algorithms based on {sup 82}Rb PET. (orig.)

Response of smooth rock skullcap (Scutellaria saxatilis), a globally rare plant, to fire

Science.gov (United States)

Cynthia D. Huebner; Kent Karriker

2015-01-01

Scutellaria saxatilis Riddell (smooth rock skullcap or rock skullcap, hereafter abbreviated as SRS), a herbaceous perennial in the mint family, is a globally rare (G3) plant. In West Virginia, SRS is categorized as an S2 species (imperiled and at high risk of extinction due to a very restricted range, very few [

SU-E-T-642: Safety Procedures for Error Elimination in Cyberknife Stereotactic Radiosurgery (SRS) and Stereotactic Body Radiation Therapy (SBRT)

International Nuclear Information System (INIS)

Hussain, A; Alkafi, A; Al-Najjar, W; Moftah, B

2014-01-01

Purpose: Cyberknife system is used for providing stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) hypofractionation scheme. The whole treatment delivery is based on live imaging of the patient. The minor error made at any stage may bring severe radiation injury to the patient or damage to the system itself. Several safety measures were taken to make the system safer. Methods: The radiation treatment provided thru a 6MV linac attached to Kuka robot (Cyberknife G4, Accuray Inc. Sunnyvale, CA, USA). Several possible errors were identified related to patient alignment, treatment planning, dose delivery and physics quality assurance. During dose delivery, manual and visual checks were introduced to confirm pre and intra-treatment imaging to reduce possible errors. One additional step was introduced to confirm that software tracking-tools had worked correctly with highest possible confidence level. Robotic head move in different orientations over and around the patient body, the rigidity of linac-head cover and other accessories was checked periodically. The vender was alerted when a tiny or bigger piece of equipment needed additional interlocked support. Results: As of our experience treating 525 patients on Cyberknife during the last four years, we saw on and off technical issues. During image acquisition, it was made essential to follow the site-specific imaging protocols. Adequate anatomy was contoured to document the respective doses. Followed by auto-segmentation, manual tweaking was performed on every structure. The calculation box was enclosing the whole image during the final calculation. Every plan was evaluated on slice-by slice basis. To review the whole process, a check list was maintained during the physics 2nd-check. Conclusion: The implementation of manual and visual additional checks introduced along with automated checks for confirmation was found promising in terms of reduction in systematic errors and making the system

Magnetic-Field-Response Measurement-Acquisition System

Science.gov (United States)

Woodward, Stanley E.; Shams, Qamar A.; Fox, Robert L.; Taylor, Bryant D.

2006-01-01

A measurement-acquisition system uses magnetic fields to power sensors and to acquire measurements from sensors. The system alleviates many shortcomings of traditional measurement-acquisition systems, which include a finite number of measurement channels, weight penalty associated with wires, use limited to a single type of measurement, wire degradation due to wear or chemical decay, and the logistics needed to add new sensors. Eliminating wiring for acquiring measurements can alleviate potential hazards associated with wires, such as damaged wires becoming ignition sources due to arcing. The sensors are designed as electrically passive inductive-capacitive or passive inductive-capacitive-resistive circuits that produce magnetic-field-responses. One or more electrical parameters (inductance, capacitance, and resistance) of each sensor can be variable and corresponds to a measured physical state of interest. The magnetic-field- response attributes (frequency, amplitude, and bandwidth) of the inductor correspond to the states of physical properties for which each sensor measures. For each sensor, the measurement-acquisition system produces a series of increasing magnetic-field harmonics within a frequency range dedicated to that sensor. For each harmonic, an antenna electrically coupled to an oscillating current (the frequency of which is that of the harmonic) produces an oscillating magnetic field. Faraday induction via the harmonic magnetic fields produces an electromotive force and therefore a current in the sensor. Once electrically active, the sensor produces its own harmonic magnetic field as the inductor stores and releases magnetic energy. The antenna of the measurement- acquisition system is switched from a transmitting to a receiving mode to acquire the magnetic-field response of the sensor. The rectified amplitude of the received response is compared to previous responses to prior transmitted harmonics, to ascertain if the measurement system has detected a

The Institutional System of Economic Agents’ Social Responsibility

Directory of Open Access Journals (Sweden)

Frolova Elena, A.

2015-12-01

Full Text Available In this paper it was made an attempt to analyse the main characteristics of the institutional system of economic agents social responsibility. The institutional system can be described as a complex of norms, rules, regulations and enforcement mechanisms in the context of interactions and communications of economic agents. The institutional nature of social responsibility allow to solve social dilemmas through the internalization of social responsibility norms and creating social value orientations, which are determine the prosocial behaviour of economic agents. The institutional system of social responsibility was described from the methodological institutionalism point of view. Analysing this phenomenon we are required to develop research on the objects of this system (norms, regulations, behaviour, on the subjects of this system (persons, business, government and on the institutional mechanisms (internalization of social responsibility norms, promoting prosocial behaviour, adaptation and transformation of the social responsibility norms aimed to ensure the understanding of origin and significance of social responsibility for modern society.

Modelling structural systems for transient response analysis

International Nuclear Information System (INIS)

Melosh, R.J.

1975-01-01

This paper introduces and reports success of a direct means of determining the time periods in which a structural system behaves as a linear system. Numerical results are based on post fracture transient analyses of simplified nuclear piping systems. Knowledge of the linear response ranges will lead to improved analysis-test correlation and more efficient analyses. It permits direct use of data from physical tests in analysis and simplication of the analytical model and interpretation of its behavior. The paper presents a procedure for deducing linearity based on transient responses. Given the forcing functions and responses of discrete points of the system at various times, the process produces evidence of linearity and quantifies an adequate set of equations of motion. Results of use of the process with linear and nonlinear analyses of piping systems with damping illustrate its success. Results cover the application to data from mathematical system responses. The process is successfull with mathematical models. In loading ranges in which all modes are excited, eight digit accuracy of predictions are obtained from the equations of motion deduced. Small changes (less than 0.01%) in the norm of the transfer matrices are produced by manipulation errors for linear systems yielding evidence that nonlinearity is easily distinguished. Significant changes (greater than five %) are coincident with relatively large norms of the equilibrium correction vector in nonlinear analyses. The paper shows that deducing linearity and, when admissible, quantifying linear equations of motion from transient response data for piping systems can be achieved with accuracy comparable to that of response data

Environmental restoration: Integrating hydraulic control of groundwater, innovative contaminant removal technologies and wetlands restoration--A case study at SRS

International Nuclear Information System (INIS)

Lewis, C.M.; Serkiz, S.M.; Adams, J.; Welty, M.

1992-01-01

The groundwater remediation program at the F and H Seepage Basins, Savannah River Sits (SRS) is a case study of the integration of various environmental restoration technologies at a single waste site. Hydraulic control measures are being designed to mitigate the discharge of groundwater plumes to surface water. One of the primary constituents of the plumes is tritium. An extraction and reinjection scenario is being designed to keep the tritium in circulation in the shallow groundwater, until it can naturally decay. This will be accomplished by extracting groundwater downgradient of the waste sites, treatment, and reinjection of the tritiated water into the water table upgradient of the basins. Innovative in-situ technologies, including electrolytic migration, are being field tested at the site to augment the pump-treat-reinject system. The in-situ technologies target removal of contaminants which are relatively immobile, yet represent long term risks to human health and the environment. Wetland restoration is an integral part of the F and H remediation program. Both in-situ treatment of the groundwater discharging the wetlands to adjust the pH, and replacement of water loss due to the groundwater extraction program ar being considered. Toxicity studies indicate that drought and the effects of low pH groundwater discharge have been factors in observed tree mortality in wetlands near the waste sites

Empirical Model Development for Predicting Shock Response on Composite Materials Subjected to Pyroshock Loading. Volume 2, Part 1; Appendices

Science.gov (United States)

Gentz, Steven J.; Ordway, David O.; Parsons, David S.; Garrison, Craig M.; Rodgers, C. Steven; Collins, Brian W.

2015-01-01

The NASA Engineering and Safety Center (NESC) received a request to develop an analysis model based on both frequency response and wave propagation analyses for predicting shock response spectrum (SRS) on composite materials subjected to pyroshock loading. The model would account for near-field environment (approximately 9 inches from the source) dominated by direct wave propagation, mid-field environment (approximately 2 feet from the source) characterized by wave propagation and structural resonances, and far-field environment dominated by lower frequency bending waves in the structure. This document contains appendices to the Volume I report.

W-026, Waste Receiving and Processing Facility data management system validation and verification report

International Nuclear Information System (INIS)

Palmer, M.E.

1997-01-01

This V and V Report includes analysis of two revisions of the DMS [data management system] System Requirements Specification (SRS) and the Preliminary System Design Document (PSDD); the source code for the DMS Communication Module (DMSCOM) messages; the source code for selected DMS Screens, and the code for the BWAS Simulator. BDM Federal analysts used a series of matrices to: compare the requirements in the System Requirements Specification (SRS) to the specifications found in the System Design Document (SDD), to ensure the design supports the business functions, compare the discreet parts of the SDD with each other, to ensure that the design is consistent and cohesive, compare the source code of the DMS Communication Module with the specifications, to ensure that the resultant messages will support the design, compare the source code of selected screens to the specifications to ensure that resultant system screens will support the design, compare the source code of the BWAS simulator with the requirements to interface with DMS messages and data transfers relating to the BWAS operations

W-026, Waste Receiving and Processing Facility data management system validation and verification report

Energy Technology Data Exchange (ETDEWEB)

Palmer, M.E.

1997-12-05

This V and V Report includes analysis of two revisions of the DMS [data management system] System Requirements Specification (SRS) and the Preliminary System Design Document (PSDD); the source code for the DMS Communication Module (DMSCOM) messages; the source code for selected DMS Screens, and the code for the BWAS Simulator. BDM Federal analysts used a series of matrices to: compare the requirements in the System Requirements Specification (SRS) to the specifications found in the System Design Document (SDD), to ensure the design supports the business functions, compare the discreet parts of the SDD with each other, to ensure that the design is consistent and cohesive, compare the source code of the DMS Communication Module with the specifications, to ensure that the resultant messages will support the design, compare the source code of selected screens to the specifications to ensure that resultant system screens will support the design, compare the source code of the BWAS simulator with the requirements to interface with DMS messages and data transfers relating to the BWAS operations.

ANALYSIS OF MONTE CARLO SIMULATION SAMPLING TECHNIQUES ON SMALL SIGNAL STABILITY OF WIND GENERATOR- CONNECTED POWER SYSTEM

Directory of Open Access Journals (Sweden)

TEMITOPE RAPHAEL AYODELE

2016-04-01

Full Text Available Monte Carlo simulation using Simple Random Sampling (SRS technique is popularly known for its ability to handle complex uncertainty problems. However, to produce a reasonable result, it requires huge sample size. This makes it to be computationally expensive, time consuming and unfit for online power system applications. In this article, the performance of Latin Hypercube Sampling (LHS technique is explored and compared with SRS in term of accuracy, robustness and speed for small signal stability application in a wind generator-connected power system. The analysis is performed using probabilistic techniques via eigenvalue analysis on two standard networks (Single Machine Infinite Bus and IEEE 16–machine 68 bus test system. The accuracy of the two sampling techniques is determined by comparing their different sample sizes with the IDEAL (conventional. The robustness is determined based on a significant variance reduction when the experiment is repeated 100 times with different sample sizes using the two sampling techniques in turn. Some of the results show that sample sizes generated from LHS for small signal stability application produces the same result as that of the IDEAL values starting from 100 sample size. This shows that about 100 sample size of random variable generated using LHS method is good enough to produce reasonable results for practical purpose in small signal stability application. It is also revealed that LHS has the least variance when the experiment is repeated 100 times compared to SRS techniques. This signifies the robustness of LHS over that of SRS techniques. 100 sample size of LHS produces the same result as that of the conventional method consisting of 50000 sample size. The reduced sample size required by LHS gives it computational speed advantage (about six times over the conventional method.

TU-CD-304-10: Development and Optimization of “Compton Lens” Collimator Design for Increased Dose Rate in SRS

Energy Technology Data Exchange (ETDEWEB)

Shepard, A; Bender, E [The University of Wisconsin-Madison, Madison, WI (United States)

2015-06-15

Purpose: To provide a proof of concept for a new collimator design to increase the dose rate at isocenter for stereotactic radiosurgery (SRS) treatments by taking advantage of off axis Compton scattered photons which are attenuated in current collimators. Methods: A fundamentally new collimator design was developed and optimized by introducing a series of slits to a standard block collimator. The introduction of slits allowed for initially off axis radiation that was scattered in the direction of the target to contribute to the target dose. For optimization, the design was broken into two parts: an upper interaction plate where primary scattering occurs, and a lower “Compton slit” region which allows for scattered photons traveling toward the target to reach isocenter. To optimize the design, a series of simulations were performed using MCNP6 in which several key parameters were adjusted and the output was compared to a standard collimator. Key parameters modified included the collimator material, cone size, and interaction plate thickness. The effects of using energies different than the traditional 6 MV beam were also explored. Results: An optimized collimator design utilizing a solid interaction plate with a Cesium-137 beam and a 4 mm cone size resulted in a dose rate increase on the order of 5% relative to standard collimators in use. Currently, designs incorporating a Cesium-137 source are the most feasible due to necessary size and weight concerns for 6 MV beams. Conclusion: Preliminary designs provide a proof of concept and indicate a potential to improve upon the dose rate of current collimators while not largely compromising the sharp dose falloff inherent to SRS. Further optimization into the geometry and positioning of the interaction plate, as well as slit optimization, will likely lead to further dose rate increases than were observed in this study. Funding for this work was provided by the Wisconsin Alumni Research Foundation (WARF). Authors have

Analysis of Gafchromic EBT3 film calibration irradiated with gamma rays from different systems: Gamma Knife and Cobalt-60 unit.

Science.gov (United States)

Najafi, Mohsen; Geraily, Ghazale; Shirazi, Alireza; Esfahani, Mahbod; Teimouri, Javad

2017-01-01

In recent years, Gafchromic films are used as an advanced instrument for dosimetry systems. The EBT3 films are a new generation of Gafchromic films. Our main interest is to compare the response of the EBT3 films exposed to gamma rays provided by the Theratron 780C as a conventional radiotherapy system and the Leksell Gamma Knife as a stereotactic radiotherapy system (SRS). Both systems use Cobalt-60 sources, thus using the same energy. However, other factors such as source-to-axis distance, number of sources, dose rate, direction of irradiation, shape of phantom, the field shape of radiation, and different scatter contribution may influence the calibration curve. Calibration curves for the 2 systems were measured and plotted for doses ranging from 0 to 40 Gy at the red and green channels. The best fitting curve was obtained with the Levenberg-Marquardt algorithm. Also, the component of dose uncertainty was obtained for any calibration curve. With the best fitting curve for the EBT3 films, we can use the calibration curve to measure the absolute dose in radiation therapy. Although there is a small deviation between the 2 curves, the p-value at any channel shows no significant difference between the 2 calibration curves. Therefore, the calibration curve for each system can be the same because of minor differences. The results show that with the best fitting curve from measured data, while considering the measurement uncertainties related to them, the EBT3 calibration curve can be used to measure the unknown dose both in SRS and in conventional radiotherapy. Copyright © 2017. Published by Elsevier Inc.

SICOEM: emergency response data system

International Nuclear Information System (INIS)

Martin, A.; Villota, C.; Francia, L.

1993-01-01

The main characteristics of the SICOEM emergency response system are: -direct electronic redundant transmission of certain operational parameters and plant status informations from the plant process computer to a computer at the Regulatory Body site, - the system will be used in emergency situations, -SICOEM is not considered as a safety class system. 1 fig

SICOEM: emergency response data system

Energy Technology Data Exchange (ETDEWEB)

Martin, A.; Villota, C.; Francia, L. (UNESA, Madrid (Spain))

1993-01-01

The main characteristics of the SICOEM emergency response system are: -direct electronic redundant transmission of certain operational parameters and plant status informations from the plant process computer to a computer at the Regulatory Body site, - the system will be used in emergency situations, -SICOEM is not considered as a safety class system. 1 fig.

GE/NOMADICS IN-WELL MONITORING SYSTEM FOR VERTICAL PROFILING OF DNAPL CONTAMINANTS

Energy Technology Data Exchange (ETDEWEB)

Ronald E. Shaffer; Radislav Potyralio; Joseph Salvo; Timothy Sivavec; Lloyd Salsman

2003-04-01

This report describes the Phase I effort to develop an Automated In Well Monitoring System (AIMS) for in situ detection of chlorinated volatile organic compounds such as trichloroethylene (TCE) and tetrachloroethylene (PCE) in groundwater. AIMS is composed of 3 primary components: (a) sensor probe, (b) instrument delivery system, and (c) communication/recharging station. The sensor probe utilizes an array of thickness shear mode (TSM) sensors coated with chemically-sensitive polymer films provides a low-cost, highly sensitive microsensor platform for detection and quantification. The instrument delivery system is used to position the sensor probe in 2 inch or larger groundwater monitoring wells. A communication/recharging station provides wireless battery recharging and communication to enable a fully automated system. A calibration curve for TCE in water was built using data collected in the laboratory. The detection limit of the sensor probe was 6.7 ppb ({micro}g/L) for TCE in water. A preliminary field test was conducted at a GE remediation location and a pilot field test was performed at the DOE Savannah River Site (SRS). The AIMS system was demonstrated in an uncontaminated (i.e., ''clean'') 2-inch well and in a 4-inch well containing 163.5 ppb of TCE. Repeat measurements at the two wells indicated excellent day-to-day reproducibility. Significant differences in the sensor responses were noted between the two types of wells but they did not closely match the laboratory calibration data. The robustness of the system presented numerous challenges for field work and limited the scope of the SRS pilot field test. However, the unique combination of trace detection (detection limits near the MCL, minimum concentration level) and size (operations in 2-inch or larger groundwater wells) is demonstration of the promise of this technology for long-term monitoring (LTM) applications or rapid site characterization. Using the lessons learned from the

Magnetic Field Response Measurement Acquisition System

Science.gov (United States)

Woodard, Stanley E.; Taylor,Bryant D.; Shams, Qamar A.; Fox, Robert L.

2007-01-01

This paper presents a measurement acquisition method that alleviates many shortcomings of traditional measurement systems. The shortcomings are a finite number of measurement channels, weight penalty associated with measurements, electrical arcing, wire degradations due to wear or chemical decay and the logistics needed to add new sensors. Wire degradation has resulted in aircraft fatalities and critical space launches being delayed. The key to this method is the use of sensors designed as passive inductor-capacitor circuits that produce magnetic field responses. The response attributes correspond to states of physical properties for which the sensors measure. Power is wirelessly provided to the sensing element by using Faraday induction. A radio frequency antenna produces a time-varying magnetic field used to power the sensor and receive the magnetic field response of the sensor. An interrogation system for discerning changes in the sensor response frequency, resistance and amplitude has been developed and is presented herein. Multiple sensors can be interrogated using this method. The method eliminates the need for a data acquisition channel dedicated to each sensor. The method does not require the sensors to be near the acquisition hardware. Methods of developing magnetic field response sensors and the influence of key parameters on measurement acquisition are discussed. Examples of magnetic field response sensors and the respective measurement characterizations are presented. Implementation of this method on an aerospace system is discussed.

Privacy preserving data anonymization of spontaneous ADE reporting system dataset.

Science.gov (United States)

Lin, Wen-Yang; Yang, Duen-Chuan; Wang, Jie-Teng

2016-07-18

To facilitate long-term safety surveillance of marketing drugs, many spontaneously reporting systems (SRSs) of ADR events have been established world-wide. Since the data collected by SRSs contain sensitive personal health information that should be protected to prevent the identification of individuals, it procures the issue of privacy preserving data publishing (PPDP), that is, how to sanitize (anonymize) raw data before publishing. Although much work has been done on PPDP, very few studies have focused on protecting privacy of SRS data and none of the anonymization methods is favorable for SRS datasets, due to which contain some characteristics such as rare events, multiple individual records, and multi-valued sensitive attributes. We propose a new privacy model called MS(k, θ (*) )-bounding for protecting published spontaneous ADE reporting data from privacy attacks. Our model has the flexibility of varying privacy thresholds, i.e., θ (*) , for different sensitive values and takes the characteristics of SRS data into consideration. We also propose an anonymization algorithm for sanitizing the raw data to meet the requirements specified through the proposed model. Our algorithm adopts a greedy-based clustering strategy to group the records into clusters, conforming to an innovative anonymization metric aiming to minimize the privacy risk as well as maintain the data utility for ADR detection. Empirical study was conducted using FAERS dataset from 2004Q1 to 2011Q4. We compared our model with four prevailing methods, including k-anonymity, (X, Y)-anonymity, Multi-sensitive l-diversity, and (α, k)-anonymity, evaluated via two measures, Danger Ratio (DR) and Information Loss (IL), and considered three different scenarios of threshold setting for θ (*) , including uniform setting, level-wise setting and frequency-based setting. We also conducted experiments to inspect the impact of anonymized data on the strengths of discovered ADR signals. With all three

Quality Assurance Results for a Commercial Radiosurgery System: A Communication.

Science.gov (United States)

Ruschin, Mark; Lightstone, Alexander; Beachey, David; Wronski, Matt; Babic, Steven; Yeboah, Collins; Lee, Young; Soliman, Hany; Sahgal, Arjun

2015-10-01

The purpose of this communication is to inform the radiosurgery community of quality assurance (QA) results requiring attention in a commercial FDA-approved linac-based cone stereo-tactic radiosurgery (SRS) system. Standard published QA guidelines as per the American Association of Physics in Medicine (AAPM) were followed during the SRS system's commissioning process including end-to-end testing, cone concentricity testing, image transfer verification, and documentation. Several software and hardware deficiencies that were deemed risky were uncovered during the process and QA processes were put in place to mitigate these risks during clinical practice. In particular, the present work focuses on daily cone concentricity testing and commissioning-related findings associated with the software. Cone concentricity/alignment is measured daily using both optical light field inspection, as well as quantitative radiation field tests with the electronic portal imager. In 10 out of 36 clini-cal treatments, adjustments to the cone position had to be made to align the cone with the collimator axis to less than 0.5 mm and on two occasions the pre-adjustment measured offset was 1.0 mm. Software-related errors discovered during commissioning included incorrect transfer of the isocentre in DICOM coordinates, improper handling of non-axial image sets, and complex handling of beam data, especially for multi-target treatments. QA processes were established to mitigate the occurrence of the software errors. With proper QA processes, the reported SRS system complies with tolerances set out in established guidelines. Discussions with the vendor are ongoing to address some of the hardware issues related to cone alignment. © The Author(s) 2014.

Comparison of local adipose tissue content and SRS-derived NIRS muscle oxygenation measurements in 90 individuals.

Science.gov (United States)

Cooper, Chris E; Penfold, Stacey-Marie; Elwell, Clare E; Angus, Caroline

2010-01-01

Adipose content in the region over the vastus lateralis muscle was measured in a young (21.1 +/- 3.1 years old, mean +/- SD) population of males (n = 62) and females (n = 28). Three techniques were used: skinfold thickness, ultrasound and near infrared spectroscopy. All techniques closely correlated with each other and all showed a significantly larger adipose content in females and a limited overlap with the range of values in males. Spatially resolved near infrared spectroscopy (SRS-NIRS) was then used to measure the tissue oxygenation index (TOI) at the same site. A source-detector separation of 4 cm was used to allow for significant light penetration into muscle tissue. TOI at rest was significantly higher in the female (65.3 +/- 7.0, mean +/- SD) than the male (61.9 +/- 5.1, mean +/- SD) group. There was a strong positive correlation between adipose content and TOI in male subjects. However, no correlation was seen in the female group. The possible optical and physiological explanations for these results are discussed.

Students Prefer Audience Response System for Lecture Evaluation

Directory of Open Access Journals (Sweden)

Joseph W Turban

2011-12-01

Full Text Available Objectives: Student evaluation of courses is an important component of overall course evaluation. The extent of student participation in the evaluation may be related to the ease of the evaluation process. The standard evaluation format is a paper form. This study examines medical students preference of utilizing Audience Response System compared to a paper method. Methods: Following several medical school lectures, students were queried if they preferred Audience Response System versus a paper method, and if they would prefer using Audience Response System more for future course evaluations. Results: 391 students were queried. Overall response rate was 94%. Using a five point Likert scale, 299 out of 361 (82% responded they agreed, or strongly agreed with the statement “We should use ARS more. . .” When asked which format they preferred to use for evaluation, 299/367 (81% responded Audience Response System, 31 (8% preferred paper, and 37 (10% were not sure, or had no opinion (chi squared = 378.936, df2, p<0.0001. Conclusion: The medical students surveyed showed a strong preference for utilizing Audience Response System as a course evaluation modality, and desired its continued use in medical school. Audience Response System should be pursued as a lecture evaluation modality, and its use in medical school education should be encouraged.

Active Response Gravity Offload System

Science.gov (United States)

Valle, Paul; Dungan, Larry; Cunningham, Thomas; Lieberman, Asher; Poncia, Dina

2011-01-01

The Active Response Gravity Offload System (ARGOS) provides the ability to simulate with one system the gravity effect of planets, moons, comets, asteroids, and microgravity, where the gravity is less than Earth fs gravity. The system works by providing a constant force offload through an overhead hoist system and horizontal motion through a rail and trolley system. The facility covers a 20 by 40-ft (approximately equals 6.1 by 12.2m) horizontal area with 15 ft (approximately equals4.6 m) of lifting vertical range.

Introduction of means of electronic study in the system of the higher education

Directory of Open Access Journals (Sweden)

Andriy Marakushyn

2015-06-01

Full Text Available Purpose: to estimate results of introduction of means of "electronic study" at physical training of students of Simon Kuznets Kharkiv national university of economics. Material and Methods: the research was conducted during 2013/14 in KhNUE among students of the first and second courses. In general for about 800 students took part in the research. Results: the system of the remote study (SRS Chamilo is characterized; the algorithm of introduction of SRS Chamilo in physical training of students is developed, applied and analysed; the analysis of the empirical data obtained as a result of the research is carried out. Conclusions: it is proved that SRS Chamilo is a platform which completely meets the demands which are made to the modern software, and can be used in physical training of students. The algorithm of its introduction to the noted sphere is logical and complete; it is established that there is an actual question of studying of motives of students of rather regular classes of physical training and sport, and also uses of means of "electronic study"; conclusions of scientists are confirmed that "electronic" communication can't replace "alive" one, and can be only its addition.

A Design of Mechanical Frequency Converter Linear and Non-linear Spring Combination for Energy Harvesting

International Nuclear Information System (INIS)

Yamamoto, K; Fujita, T; Kanda, K; Maenaka, K; Badel, A; Formosa, F

2014-01-01

In this study, the improvement of energy harvesting from wideband vibration with random change by using a combination of linear and nonlinear spring system is investigated. The system consists of curved beam spring for non-linear buckling, which supports the linear mass-spring resonator. Applying shock acceleration generates a snap through action to the buckling spring. From the FEM analysis, we showed that the snap through acceleration from the buckling action has no relationship with the applied shock amplitude and duration. We use this uniform acceleration as an impulse shock source for the linear resonator. It is easy to obtain the maximum shock response from the uniform snap through acceleration by using a shock response spectrum (SRS) analysis method. At first we investigated the relationship between the snap-through behaviour and an initial curved deflection. Then a time response result for non-linear springs with snap through and minimum force that makes a buckling behaviour were obtained by FEM analysis. By obtaining the optimum SRS frequency for linear resonator, we decided its resonant frequency with the MATLAB simulator

Step response and frequency response of an air conditioning system

NARCIS (Netherlands)

Crommelin, R.D.; Jackman, P.J.

1978-01-01

A system of induction units of an existing air conditioning system has been analyzed with respect to its dynamic properties. Time constants were calculated and measured by analogue models. Comparison with measurements at the installation itself showed a reasonable agreement. Frequency responses were

RF Control System Upgrade at CAMD

CERN Document Server

Suller, Victor P; Jines, Paul; Launey, Daren

2005-01-01

A description is given of the new control system for the RF system of the CAMD light source. The new design being implemented brings all RF signals into the data acquisition system via a modular, custom made, RF detector and renders the amplitude and tune control loops in the VME computer. On line calculations ensure monitoring of proper operation and display the information to the user in an efficient way. In addition, an advanced load impedance monitoring diagnostic has been implemented, being displayed as a Smith Chart, which is based on the system used at the SRS in Daresbury, England.

Emergency response and radiation monitoring systems in Russian regions

International Nuclear Information System (INIS)

Arutyunyan, R.; Osipiyants, I.; Kiselev, V.; Ogar, K; Gavrilov, S.

2008-01-01

Full text: Preparedness of the emergency response system to elimination of radiation incidents and accidents is one of the most important elements of ensuring safe operation of nuclear power facilities. Routine activities on prevention of emergency situations along with adequate, efficient and opportune response actions are the key factors reducing the risks of adverse effects on population and environment. Both high engineering level and multiformity of the nuclear branch facilities make special demands on establishment of response system activities to eventual emergency situations. First and foremost, while resolving sophisticated engineering and scientific problems emerging during the emergency response process, one needs a powerful scientific and technical support system.The emergency response system established in the past decade in Russian nuclear branch provides a high efficiency of response activities due to the use of scientific and engineering potential and experience of the involved institutions. In Russia the responsibility for population protection is imposed on regional authority. So regional emergence response system should include up-to-date tools of radiation monitoring and infrastructure. That's why new activities on development of radiation monitoring and emergency response system were started in the regions of Russia. The main directions of these activities are: 1) Modernization of the existing and setting-up new facility and territorial automatic radiation monitoring systems, including mobile radiation surveillance kits; 2) Establishment of the Regional Crisis Centres and Crisis Centres of nuclear and radiation hazardous facilities; 3) Setting up communication systems for transfer, acquisition, processing, storage and presentation of data for participants of emergency response at the facility, regional and federal levels; 4) Development of software and hardware systems for expert support of decision-making on protection of personnel, population

Performance of integrated systems of automated roller shade systems and daylight responsive dimming systems

Energy Technology Data Exchange (ETDEWEB)

Park, Byoung-Chul; Choi, An-Seop; Jeong, Jae-Weon [Department of Architectural Engineering, Sejong University, Kunja-Dong, Kwangjin-Gu, Seoul (Korea, Republic of); Lee, Eleanor S. [Building Technologies Department, Lawrence Berkeley National Laboratory, Berkeley, CA (United States)

2011-03-15

Daylight responsive dimming systems have been used in few buildings to date because they require improvements to improve reliability. The key underlying factor contributing to poor performance is the variability of the ratio of the photosensor signal to daylight workplane illuminance in accordance with sun position, sky condition, and fenestration condition. Therefore, this paper describes the integrated systems between automated roller shade systems and daylight responsive dimming systems with an improved closed-loop proportional control algorithm, and the relative performance of the integrated systems and single systems. The concept of the improved closed-loop proportional control algorithm for the integrated systems is to predict the varying correlation of photosensor signal to daylight workplane illuminance according to roller shade height and sky conditions for improvement of the system accuracy. In this study, the performance of the integrated systems with two improved closed-loop proportional control algorithms was compared with that of the current (modified) closed-loop proportional control algorithm. In the results, the average maintenance percentage and the average discrepancies of the target illuminance, as well as the average time under 90% of target illuminance for the integrated systems significantly improved in comparison with the current closed-loop proportional control algorithm for daylight responsive dimming systems as a single system. (author)

Systemic model for the aid for operating of the reactor Siloe; Modelisation systeme pour l`aide a l`exploitation du reacteur de recherche Siloe

Energy Technology Data Exchange (ETDEWEB)

Royer, J.C.; Moulin, V.; Monge, F. [CEA Centre d`Etudes de Grenoble, 38 (France). Direction des Reacteurs Nucleaires; Baradel, C. [ITMI APTOR, 38 - Meylan (France)

1995-12-31

The Service of the Reactor Siloe (CEA/DRN/DRE/SRS), fully aware of the abilities and knowledge of his teams in the field of research reactor operating, has undertaken a project of knowledge engineering in this domain. The following aims have been defined: knowledge capitalization for the installation in order to insure its perenniality and valorization, elaboration of a project for the aid of the reactor operators. This article deals with the different actions by the SRS to reach the aims: realization of a technical model for the operation of the Siloe reactor, development of a knowledge-based system for the aid for operating. These actions based on a knowledge engineering methodology, SAGACE, and using industrial tools will lead to an amelioration of the security and the operating of the Siloe reactor. (authors). 13 refs., 7 figs.

Software qualification for digital safety system in KNICS project

International Nuclear Information System (INIS)

Kwon, Kee-Choon; Lee, Dong-Young; Choi, Jong-Gyun

2012-01-01

In order to achieve technical self-reliance in the area of nuclear instrumentation and control, the Korea Nuclear Instrumentation and Control System (KNICS) project had been running for seven years from 2001. The safety-grade Programmable Logic Controller (PLC) and the digital safety system were developed by KNICS project. All the software of the PLC and digital safety system were developed and verified following the software development life cycle Verification and Validation (V and V) procedure. The main activities of the V and V process are preparation of software planning documentations, verification of the Software Requirement Specification (SRS), Software Design Specification (SDS) and codes, and a testing of the software components, the integrated software, and the integrated system. In addition, a software safety analysis and a software configuration management are included in the activities. For the software safety analysis at the SRS and SDS phases, the software Hazard Operability (HAZOP) was performed and then the software fault tree analysis was applied. The software fault tree analysis was applied to a part of software module with some critical defects identified by the software HAZOP in SDS phase. The software configuration management was performed using the in-house tool developed in the KNICS project. (author)

Linear optical response of finite systems using multishift linear system solvers

Energy Technology Data Exchange (ETDEWEB)

Hübener, Hannes; Giustino, Feliciano [Department of Materials, University of Oxford, Oxford OX1 3PH (United Kingdom)

2014-07-28

We discuss the application of multishift linear system solvers to linear-response time-dependent density functional theory. Using this technique the complete frequency-dependent electronic density response of finite systems to an external perturbation can be calculated at the cost of a single solution of a linear system via conjugate gradients. We show that multishift time-dependent density functional theory yields excitation energies and oscillator strengths in perfect agreement with the standard diagonalization of the response matrix (Casida's method), while being computationally advantageous. We present test calculations for benzene, porphin, and chlorophyll molecules. We argue that multishift solvers may find broad applicability in the context of excited-state calculations within density-functional theory and beyond.

Conventional estimating method of earthquake response of mechanical appendage system

International Nuclear Information System (INIS)

Aoki, Shigeru; Suzuki, Kohei

1981-01-01

Generally, for the estimation of the earthquake response of appendage structure system installed in main structure system, the method of floor response analysis using the response spectra at the point of installing the appendage system has been used. On the other hand, the research on the estimation of the earthquake response of appendage system by the statistical procedure based on probability process theory has been reported. The development of a practical method for simply estimating the response is an important subject in aseismatic engineering. In this study, the method of estimating the earthquake response of appendage system in the general case that the natural frequencies of both structure systems were different was investigated. First, it was shown that floor response amplification factor was able to be estimated simply by giving the ratio of the natural frequencies of both structure systems, and its statistical property was clarified. Next, it was elucidated that the procedure of expressing acceleration, velocity and displacement responses with tri-axial response spectra simultaneously was able to be applied to the expression of FRAF. The applicability of this procedure to nonlinear system was examined. (Kako, I.)

Information Systems Security: Whose Responsibility? | Senzige ...

African Journals Online (AJOL)

... compounded by the increasingly international nature of information systems, this responsibility still rests with managers only. This paper looks at security concerns related to information systems, identifies the threats and suggests how the security of information systems should be handled. African Journal of Finance and ...

Accuracy evaluation of fusion of CT, MR, and SPECT images using commercially available software packages (SRS PLATO and IFS)

International Nuclear Information System (INIS)

Mongioj, Valeria; Brusa, Anna; Loi, Gianfranco; Pignoli, Emanuele; Gramaglia, Alberto; Scorsetti, Marta; Bombardieri, Emilio; Marchesini, Renato

1999-01-01

Purpose: A problem for clinicians is to mentally integrate information from multiple diagnostic sources, such as computed tomography (CT), magnetic resonance (MR), and single photon emission computed tomography (SPECT), whose images give anatomic and metabolic information. Methods and Materials: To combine this different imaging procedure information, and to overlay correspondent slices, we used commercially available software packages (SRS PLATO and IFS). The algorithms utilize a fiducial-based coordinate system (or frame) with 3 N-shaped markers, which allows coordinate transformation of a clinical examination data set (9 spots for each transaxial section) to a stereotactic coordinate system. The N-shaped markers were filled with fluids visible in each modality (gadolinium for MR, calcium chloride for CT, and 99m Tc for SPECT). The frame is relocatable, in the different acquisition modalities, by means of a head holder to which a face mask is fixed so as to immobilize the patient. Position errors due to the algorithms were obtained by evaluating the stereotactic coordinates of five sources detectable in each modality. Results: SPECT and MR position errors due to the algorithms were evaluated with respect to CT: Δx was ≤ 0.9 mm for MR and ≤ 1.4 mm for SPECT, Δy was ≤ 1 mm and ≤ 3 mm for MR and SPECT, respectively. Maximal differences in distance between estimated and actual fiducial centers (geometric mismatch) were in the order of the pixel size (0.8 mm for CT, 1.4 mm for MR, and 1.8 mm for SPECT). In an attempt to distinguish necrosis from residual disease, the image fusion protocol was studied in 35 primary or metastatic brain tumor patients. Conclusions: The image fusion technique has a good degree of accuracy as well as the potential to improve the specificity of tissue identification and the precision of the subsequent treatment planning

Refinement for Transition Systems with Responses

Directory of Open Access Journals (Sweden)

Marco Carbone

2012-07-01

Full Text Available Motivated by the response pattern for property specifications and applications within flexible workflow management systems, we report upon an initial study of modal and mixed transition systems in which the must transitions are interpreted as must eventually, and in which implementations can contain may behaviors that are resolved at run-time. We propose Transition Systems with Responses (TSRs as a suitable model for this study. We prove that TSRs correspond to a restricted class of mixed transition systems, which we refer to as the action-deterministic mixed transition systems. We show that TSRs allow for a natural definition of deadlocked and accepting states. We then transfer the standard definition of refinement for mixed transition systems to TSRs and prove that refinement does not preserve deadlock freedom. This leads to the proposal of safe refinements, which are those that preserve deadlock freedom. We exemplify the use of TSRs and (safe refinements on a small medication workflow.

Validation of a Japanese version of the Scoliosis Research Society-22 Patient Questionnaire among idiopathic scoliosis patients in Japan.

Science.gov (United States)

Hashimoto, Hideki; Sase, Takeshi; Arai, Yasuhisa; Maruyama, Toru; Isobe, Keijirou; Shouno, Yasuhiro

2007-02-15

A cross-sectional observational study to determine the response distribution, internal consistency, and construct, concurrent, and discriminative validities of The Scoliosis Research Society-22 (SRS-22) Patient Questionnaire translated into Japanese as compared with the other language versions. To validate the Japanese version of SRS22. The SRS-22 was translated into several languages but yet not into Japanese. The Japanese SRS-22 and Medical Outcomes Study Short Form 36 were simultaneously administered to 114 adolescent idiopathic scoliosis patients. Exploratory factor analysis revealed a 4-factor structure, though several items were not loaded as theoretically expected. The originally constructed Japanese SRS-22 subscales and the English version showed similar response distribution. Internal consistency was fair but lower than that of the English version. The concurrent validity of the translated version, except for the self-image subscale, was supported using Medical Outcomes Study Short Form 36 subscales as a reference. The function scale differed significantly by curve angle magnitude and treatment status. The self-image score was the highest in patients under observation when curve angle was or = 40 degrees, respectively. The Japanese SRS-22 is valid and may be useful for clinical evaluation of Japanese scoliosis patients, though the self-image subscale may need further assessment.

Designing effective questions for classroom response system teaching

Science.gov (United States)

Beatty, Ian D.; Gerace, William J.; Leonard, William J.; Dufresne, Robert J.

2006-01-01

Classroom response systems can be powerful tools for teaching physics. Their efficacy depends strongly on the quality of the questions. Creating effective questions is difficult and differs from creating exam and homework problems. Each classroom response system question should have an explicit pedagogic purpose consisting of a content goal, a process goal, and a metacognitive goal. Questions can be designed to fulfill their purpose through four complementary mechanisms: directing students' attention, stimulating specific cognitive processes, communicating information to the instructor and students via classroom response system-tabulated answer counts, and facilitating the articulation and confrontation of ideas. We identify several tactics that are useful for designing potent questions and present four "makeovers" to show how these tactics can be used to convert traditional physics questions into more powerful questions for a classroom response system.

Effectiveness of Treatment of Idiopathic Scoliosis by SpineCor Dynamic Bracing with Special Physiotherapy Programme in SpineCor System.

Science.gov (United States)

Rożek, Karina; Potaczek, Tomasz; Zarzycka, Maja; Lipik, Ewa; Jasiewicz, Barbara

2016-10-28

The SpineCor dynamic brace for the treatment of idiopathic scoliosis is designed to maintain the correct position of the spine and a new movement strategy for 20 hours per day. The SpineCor exercise system intensifies and complements the brace treatment. This study evaluated the effectiveness of a comprehensive treatment of idiopathic scoliosis involving the SpineCor system. The study assessed a group of 40 patients (38 girls and 2 boys) with idiopathic scoliosis treated with the SpineCor brace. The average age at beginning of treatment was 13.1 yrs (10-15). Minimum treatment time was 18 months. 28 participants met the SRS criteria. Angles of the curve before and after bracing based on imaging studies were measured at the beginning and end of the treatment, analyzed and compared. Rehabilitation focused on teaching active corrective movement throughout the brace treatment. A control group was formed of 33 patients, including 21 meeting the SRS criteria, who used the SpineCor dynamic brace but did not participate in the associated exercise programme. Among patients from the exercise group who met the SRS criteria, 25% demonstrated reduced curve angles, 35.7% demonstrated curve progression and 39.3% showed stabilization (no change). Among patients meeting the SRS criteria from the control group, a decrease in curve angle was observed in 14.3% of the patients, curve progression in 57.1% and stabilization in 28.6%. 1. The addition of a dedicated physiotherapy programme to SpineCor dynamic bracing improves the chances of obtaining a positive outcome. 2. It is necessary to further analyse the course of the comprehensive treatment, also with regard to other types of braces and kinesiotherapy programmes.

LOFT system structural response during subcooled blowdown

International Nuclear Information System (INIS)

Martinell, J.S.

1978-01-01

The Loss-of-Fluid Test (LOFT) facility is a highly instrumented, pressurized water reactor test system designed to be representative of large pressurized water reactors (LPWRs) for the simulation of loss-of-coolant accidents (LOCAs). Detailed structural analysis and appropriate instrumentation (accelerometers and strain gages) on the LOFT system provided information for evaluation of the structural response of the LOFT facility for loss-of-coolant experiment (LOCE) induced loads. In general, the response of the system during subcooled blowdown was small with typical structural accelerations below 2.0 G's and dynamic strains less than 150 x 10 - 6 m/m. The accelerations measured at the steam generator and simulated steam generator flange exceeded LOCE design values; however, integration of the accelerometer data at these locations yielded displacements which were less than one half of the design values associated with a safe shutdown earthquake (SSE), which assures structural integrity for LOCE loads. The existing measurement system was adequate for evaluation of the LOFT system response during the LOCEs. The conditions affecting blowdown loads during nuclear LOCEs will be nearly the same as those experienced during the nonnuclear LOCEs, and the characteristics of the structural response data in both types of experiments are expected to be the same. The LOFT system is concluded to be adequately designed and further analysis of the LOFT system with structural codes is not required for future LOCE experiments

Crowdsourced validation of a machine-learning classification system for autism and ADHD.

Science.gov (United States)

Duda, M; Haber, N; Daniels, J; Wall, D P

2017-05-16

Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) together affect >10% of the children in the United States, but considerable behavioral overlaps between the two disorders can often complicate differential diagnosis. Currently, there is no screening test designed to differentiate between the two disorders, and with waiting times from initial suspicion to diagnosis upwards of a year, methods to quickly and accurately assess risk for these and other developmental disorders are desperately needed. In a previous study, we found that four machine-learning algorithms were able to accurately (area under the curve (AUC)>0.96) distinguish ASD from ADHD using only a small subset of items from the Social Responsiveness Scale (SRS). Here, we expand upon our prior work by including a novel crowdsourced data set of responses to our predefined top 15 SRS-derived questions from parents of children with ASD (n=248) or ADHD (n=174) to improve our model's capability to generalize to new, 'real-world' data. By mixing these novel survey data with our initial archival sample (n=3417) and performing repeated cross-validation with subsampling, we created a classification algorithm that performs with AUC=0.89±0.01 using only 15 questions.

Frequency response functions for nonlinear convergent systems

NARCIS (Netherlands)

Pavlov, A.V.; Wouw, van de N.; Nijmeijer, H.

2007-01-01

Convergent systems constitute a practically important class of nonlinear systems that extends the class of asymptotically stable linear time-invariant systems. In this note, we extend frequency response functions defined for linear systems to nonlinear convergent systems. Such nonlinear frequency

The TransPetro emergency response system

Energy Technology Data Exchange (ETDEWEB)

Filho, A.T.F.; Cardoso, V.F.; Carbone, R.; Berardinelli, R.P. [Petrobras-TransPetro, Rio de Janeiro (Brazil); Carvalho, M.T.M.; Casanova, M.A. [Pontificia Univ. Catolica, Rio de Janeiro (Brazil). Dept. de Informatica, TeCGraf

2004-07-01

Petrobras-TransPetro developed the TransPetro Emergency Response System in response to emergency situations at large oil pipelines or at terminal facilities located in sea or river harbour areas. The standard of excellence includes full compliance with environmental regulations set by the federal government. A distributed workflow management software called InfoPAE forms the basis of the system in which actions are defined, along with geographic and conventional data. The first prototype of InfoPAE was installed in 1999. Currently it is operational in nearly 80 installations. The basic concepts and functionality of the TransPetro Emergency Response System were outlined in this paper with reference to the mitigative actions that are based on an evaluation of the organization of the emergency teams; the communication procedures; characterization of the installations; definition of accidental scenarios; environmental sensitivity maps; simulation of oil spill trajectories and dispersion behaviour; geographical data of the area surrounding the installations; and, other conventional data related to the installations, including available equipment. The emergency response team can take action as soon as an accident is detected. The action plan involves characterizing several scenarios and delegating mitigative actions to specific sub-teams, each with access to geographic data on the region where the emergency occurred. 13 refs., 3 figs.

Tone and call responses of units in the auditory nerve and dorsal medullary nucleus of Xenopus laevis

DEFF Research Database (Denmark)

Elliott, Taffeta M.; Christensen-Dalsgaard, Jakob; Kelley, Darcy B.

2007-01-01

The clawed frog Xenopus laevis produces vocalizations consisting of distinct patterns of clicks. This study provides the first description of spontaneous, pure-tone and communication-signal evoked discharge properties of auditory nerve (n.VIII) fibers and dorsal medullary nucleus (DMN) cells...... in an obligatorily aquatic anuran. Responses of 297 n.VIII and 253 DMN units are analyzed for spontaneous rates (SR), frequency tuning, rate-intensity functions, and firing rate adaptation, with a view to how these basic characteristics shape responses to recorded call stimuli. Response properties generally resemble......Hz with approximately 500 Hz in 3 dB bandwidth. SRs range from 0 to 80 (n.VIII) and 0 to 73 spikes/s (DMN). Nerve and DMN units of all CFs follow click rates in natural calls,

Investigation of the thermal mixing in a T-junction flow with different SRS approaches

Energy Technology Data Exchange (ETDEWEB)

Gritskevich, M.S., E-mail: gritskevich@ymail.com [St. Petersburg State Polytechnical University, 195251 St. Petersburg (Russian Federation); Garbaruk, A.V. [St. Petersburg State Polytechnical University, 195251 St. Petersburg (Russian Federation); Frank, Th.; Menter, F.R. [Software Development Department, ANSYS, 83714 Otterfing (Germany)

2014-11-15

Highlights: • Global (SAS, DDES) and zonal (ELES-WMLES) models are compared for the T-junction flow. • All the models accurately predict mean, RMS, and spectral quantities. • ELES-WMLES approach yields very good results independent of the advection scheme. • SAS and the DDES models are slightly less accurate. • SAS depends on the advection scheme. - Abstract: An investigation of different turbulence Scale-Resolving Simulation (SRS) modeling approaches for the flow in a T-junction has been conducted using the Scale-Adaptive Simulation (SAS), the Delayed Detached Eddy Simulation (DDES) and the Embedded Large Eddy Simulation (ELES) methods. The results show that all models are able to accurately predict mean and RMS velocity profiles and velocity spectra, when are used in combination with a low dissipation advection scheme. However, when a slightly more dissipative scheme is used, the SAS model yields less accurate results, indicating that this flow does not produce a strong enough flow instability to allow the safe application of this model. The DDES and the ELES models show less sensitivity to the numerical setting compared to the SAS model. The main goal of the study is the accurate prediction of heat transfer on the walls in the mixing zone. In that respect, the ELES method produces the most consistent agreement with the experimental data.

Error response test system and method using test mask variable

Science.gov (United States)

Gender, Thomas K. (Inventor)

2006-01-01

An error response test system and method with increased functionality and improved performance is provided. The error response test system provides the ability to inject errors into the application under test to test the error response of the application under test in an automated and efficient manner. The error response system injects errors into the application through a test mask variable. The test mask variable is added to the application under test. During normal operation, the test mask variable is set to allow the application under test to operate normally. During testing, the error response test system can change the test mask variable to introduce an error into the application under test. The error response system can then monitor the application under test to determine whether the application has the correct response to the error.

[Selected enhancement of different order stokes lines of SRS by using fluorescence of mixed dye solution].

Science.gov (United States)

Zuo, Hao-yi; Gao, Jie; Yang, Jing-guo

2007-03-01

A new method to enhance the intensity of the different orders of Stokes lines of SRS by using mixed dye fluorescence is reported. The Stokes lines from the second-order to the fifth-order of CCl4 were enhanced by the fluorescence of mixed R6G and RB solutions in different proportions of 20:2, 20:13 and 20:40 (R6g:Rb), respectively. It is considered that the Stokes lines from the second-order to the fifth-order are near the fluorescence peaks of the three mixed solutions, and far from the absorption peaks of R6g and Rb, so the enhancement effect dominates the absorption effect; as a result, these stokes lines are enhanced. On the contrary, the first-order stokes line is near the absorption peak of RB and far from the fluorescence peaks of the mixed solutions, which leads to the weakening of this stokes line. It is also reported that the first-order, the second-order and the third-order Stokes lines of benzene were enhanced by the fluorescence of mixed solutions of R6g and DCM with of different proportions. The potential application of this method is forecasted.

Demand Response as a System Reliability Resource

Energy Technology Data Exchange (ETDEWEB)

Eto, Joseph H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Lewis, Nancy Jo [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Watson, David [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Kiliccote, Sila [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Auslander, David [Univ. of California, Berkeley, CA (United States); Paprotny, Igor [Univ. of California, Berkeley, CA (United States); Makarov, Yuri [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2012-12-31

The Demand Response as a System Reliability Resource project consists of six technical tasks: • Task 2.1. Test Plan and Conduct Tests: Contingency Reserves Demand Response (DR) Demonstration—a pioneering demonstration of how existing utility load-management assets can provide an important electricity system reliability resource known as contingency reserve. • Task 2.2. Participation in Electric Power Research Institute (EPRI) IntelliGrid—technical assistance to the EPRI IntelliGrid team in developing use cases and other high-level requirements for the architecture. • Task 2.3. Research, Development, and Demonstration (RD&D) Planning for Demand Response Technology Development—technical support to the Public Interest Energy Research (PIER) Program on five topics: Sub-task 1. PIER Smart Grid RD&D Planning Document; Sub-task 2. System Dynamics of Programmable Controllable Thermostats; Sub-task 3. California Independent System Operator (California ISO) DR Use Cases; Sub-task 4. California ISO Telemetry Requirements; and Sub-task 5. Design of a Building Load Data Storage Platform. • Task 2.4. Time Value of Demand Response—research that will enable California ISO to take better account of the speed of the resources that it deploys to ensure compliance with reliability rules for frequency control. • Task 2.5. System Integration and Market Research: Southern California Edison (SCE)—research and technical support for efforts led by SCE to conduct demand response pilot demonstrations to provide a contingency reserve service (known as non-spinning reserve) through a targeted sub-population of aggregated residential and small commercial customers enrolled in SCE’s traditional air conditioning (AC) load cycling program, the Summer Discount Plan. • Task 2.6. Demonstrate Demand Response Technologies: Pacific Gas and Electric (PG&E)—research and technical support for efforts led by PG&E to conduct a demand response pilot demonstration to provide non

A Tactical Emergency Response Management System (Terms ...

African Journals Online (AJOL)

2013-03-01

Mar 1, 2013 ... information is a result of collaboration between accident response personnel. ... Tactical Emergency Response Management System (TERMS) which unifies all these different ... purpose of handling crisis and emergency.

Dental caries imaging using hyperspectral stimulated Raman scattering microscopy

Science.gov (United States)

Wang, Zi; Zheng, Wei; Jian, Lin; Huang, Zhiwei

2016-03-01

We report the development of a polarization-resolved hyperspectral stimulated Raman scattering (SRS) imaging technique based on a picosecond (ps) laser-pumped optical parametric oscillator system for label-free imaging of dental caries. In our imaging system, hyperspectral SRS images (512×512 pixels) in both fingerprint region (800-1800 cm-1) and high-wavenumber region (2800-3600 cm-1) are acquired in minutes by scanning the wavelength of OPO output, which is a thousand times faster than conventional confocal micro Raman imaging. SRS spectra variations from normal enamel to caries obtained from the hyperspectral SRS images show the loss of phosphate and carbonate in the carious region. While polarization-resolved SRS images at 959 cm-1 demonstrate that the caries has higher depolarization ratio. Our results demonstrate that the polarization resolved-hyperspectral SRS imaging technique developed allows for rapid identification of the biochemical and structural changes of dental caries.

Trigeminal Neuralgia Treated With Stereotactic Radiosurgery: The Effect of Dose Escalation on Pain Control and Treatment Outcomes

Energy Technology Data Exchange (ETDEWEB)

Kotecha, Rupesh [Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio (United States); Kotecha, Ritesh [MidMichigan Medical Center, Midland, Michigan (United States); Modugula, Sujith [Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio (United States); Murphy, Erin S. [Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio (United States); Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, Ohio (United States); Jones, Mark; Kotecha, Rajesh [MidMichigan Medical Center, Midland, Michigan (United States); Reddy, Chandana A. [Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio (United States); Suh, John H. [Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio (United States); Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, Ohio (United States); Barnett, Gene H. [Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, Ohio (United States); Department of Neurosurgery, Neurological Institute, Cleveland Clinic, Cleveland, Ohio (United States); Neyman, Gennady [Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio (United States); Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, Ohio (United States); Machado, Andre; Nagel, Sean [Department of Neurosurgery, Neurological Institute, Cleveland Clinic, Cleveland, Ohio (United States); Chao, Samuel T., E-mail: chaos@ccf.org [Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio (United States); Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, Ohio (United States)

2016-09-01

Purpose: To analyze the effect of dose escalation on treatment outcome in patients undergoing stereotactic radiosurgery (SRS) for trigeminal neuralgia (TN). Methods and Materials: A retrospective review was performed of 870 patients who underwent SRS for a diagnosis of TN from 2 institutions. Patients were typically treated using a single 4-mm isocenter placed at the trigeminal nerve dorsal root entry zone. Patients were divided into groups based on treatment doses: ≤82 Gy (352 patients), 83 to 86 Gy (85 patients), and ≥90 Gy (433 patients). Pain response was classified using a categorical scoring system, with fair or poor pain control representing treatment failure. Treatment-related facial numbness was classified using the Barrow Neurological Institute scale. Log-rank tests were performed to test differences in time to pain failure or development of facial numbness for patients treated with different doses. Results: Median age at first pain onset was 63 years, median age at time of SRS was 71 years, and median follow-up was 36.5 months from the time of SRS. A majority of patients (827, 95%) were clinically diagnosed with typical TN. The 4-year rate of excellent to good pain relief was 87% (95% confidence interval 84%-90%). The 4-year rate of pain response was 79%, 82%, and 92% in patients treated to ≤82 Gy, 83 to 86 Gy, and ≥90 Gy, respectively. Patients treated to doses ≤82 Gy had an increased risk of pain failure after SRS, compared with patients treated to ≥90 Gy (hazard ratio 2.0, P=.0007). Rates of treatment-related facial numbness were similar among patients treated to doses ≥83 Gy. Nine patients (1%) were diagnosed with anesthesia dolorosa. Conclusions: Dose escalation for TN to doses >82 Gy is associated with an improvement in response to treatment and duration of pain relief. Patients treated at these doses, however, should be counseled about the increased risk of treatment-related facial numbness.

Trigeminal Neuralgia Treated With Stereotactic Radiosurgery: The Effect of Dose Escalation on Pain Control and Treatment Outcomes

International Nuclear Information System (INIS)

Kotecha, Rupesh; Kotecha, Ritesh; Modugula, Sujith; Murphy, Erin S.; Jones, Mark; Kotecha, Rajesh; Reddy, Chandana A.; Suh, John H.; Barnett, Gene H.; Neyman, Gennady; Machado, Andre; Nagel, Sean; Chao, Samuel T.

2016-01-01

Purpose: To analyze the effect of dose escalation on treatment outcome in patients undergoing stereotactic radiosurgery (SRS) for trigeminal neuralgia (TN). Methods and Materials: A retrospective review was performed of 870 patients who underwent SRS for a diagnosis of TN from 2 institutions. Patients were typically treated using a single 4-mm isocenter placed at the trigeminal nerve dorsal root entry zone. Patients were divided into groups based on treatment doses: ≤82 Gy (352 patients), 83 to 86 Gy (85 patients), and ≥90 Gy (433 patients). Pain response was classified using a categorical scoring system, with fair or poor pain control representing treatment failure. Treatment-related facial numbness was classified using the Barrow Neurological Institute scale. Log-rank tests were performed to test differences in time to pain failure or development of facial numbness for patients treated with different doses. Results: Median age at first pain onset was 63 years, median age at time of SRS was 71 years, and median follow-up was 36.5 months from the time of SRS. A majority of patients (827, 95%) were clinically diagnosed with typical TN. The 4-year rate of excellent to good pain relief was 87% (95% confidence interval 84%-90%). The 4-year rate of pain response was 79%, 82%, and 92% in patients treated to ≤82 Gy, 83 to 86 Gy, and ≥90 Gy, respectively. Patients treated to doses ≤82 Gy had an increased risk of pain failure after SRS, compared with patients treated to ≥90 Gy (hazard ratio 2.0, P=.0007). Rates of treatment-related facial numbness were similar among patients treated to doses ≥83 Gy. Nine patients (1%) were diagnosed with anesthesia dolorosa. Conclusions: Dose escalation for TN to doses >82 Gy is associated with an improvement in response to treatment and duration of pain relief. Patients treated at these doses, however, should be counseled about the increased risk of treatment-related facial numbness.

NESHAP Area-Specific Dose-Release Factors for Potential Onsite Member-of-the-Public Locations at SRS using CAP88-PC Version 4.0

Energy Technology Data Exchange (ETDEWEB)

Trimor, P. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2017-08-09

The Environmental Protection Agency (EPA) requires the use of the computer model CAP88-PC to estimate the total effective doses (TED) for demonstrating compliance with 40 CFR 61, Subpart H (EPA 2006), the National Emission Standards for Hazardous Air Pollutants (NESHAP) regulations. As such, CAP88 Version 4.0 was used to calculate the receptor dose due to routine atmospheric releases at the Savannah River Site (SRS). For estimation, NESHAP dose-release factors (DRFs) have been supplied to Environmental Compliance and Area Closure Projects (EC&ACP) for many years. DRFs represent the dose to a maximum receptor exposed to 1 Ci of a specified radionuclide being released into the atmosphere. They are periodically updated to include changes in the CAP88 version, input parameter values, site meteorology, and location of the maximally exposed individual (MEI). In this report, the DRFs were calculated for potential radionuclide atmospheric releases from 13 SRS release points. The three potential onsite MEI locations to be evaluated are B-Area, Three Rivers Landfill (TRL), and Savannah River Ecology Lab Conference Center (SRELCC) with TRL’s onsite workers considered as members-of-the-public, and the potential future constructions of dormitories at SRELCC and Barracks at B-Area. Each MEI location was evaluated at a specified compass sector with different area to receptor distances and was conducted for both ground-level and elevated release points. The analysis makes use of area-specific meteorological data (Viner 2014). The resulting DRFs are compared to the 2014 NESHAP offsite MEI DRFs for three operational areas; A-Area, H-Area, and COS for a release rate of 1 Ci of tritium oxide at 0 ft. elevation. CAP88 was executed again using the 2016 NESHAP MEI release rates for 0 and 61 m stack heights to determine the radionuclide dose at TRL from the center-of-site (COS).

Coexistence of ferromagnetism and unconventional spin-glass freezing in the site-disordered kagome ferrite SrS n2F e4O11

Science.gov (United States)

Shlyk, L.; Strobel, S.; Farmer, B.; De Long, L. E.; Niewa, R.

2018-02-01

Single-crystal x-ray diffraction refinements indicate SrS n2F e4O11 crystallizes in the hexagonal R -type ferrite structure with noncentrosymmetric space group P 63m c and lattice parameters a =5.9541 (2 )Å , c =13.5761 (5 )Å , Z =2 (R (F )=0.034 ). Octahedrally coordinated 2 a [M (1) and M (1a)] and 6 c sites [M (2 )] have random, mixed occupation by Sn and Fe; whereas the tetrahedrally coordinated 2 b sites [Fe(3) and Fe(3a)] are exclusively occupied by Fe, whose displacement from the ideal position with trigonal-bipyramidal coordination causes the loss of inversion symmetry. Our dc and ac magnetization data indicate SrS n2F e4O11 single crystals undergo a ferro- or ferri-magnetic transition below a temperature TC=630 K with very low coercive fields μoHc ⊥=0.27 Oe and μoHc ∥=1.5 Oe at 300 K, for applied field perpendicular and parallel to the c axis, respectively. The value for TC is exceptionally high, and the coercive fields exceptionally low, among the known R-type ferrites. Time-dependent dc magnetization and frequency-dependent ac magnetization data indicate the onset of short-range, spin-glass freezing below Tf=35.8 K , which results from crystallographic disorder of magnetic F e3 + and nonmagnetic S n4 + ions on a frustrated Kagome sublattice. Anomalous ac susceptibility and thermomagnetic relaxation behavior in the short-range-ordered state differs from that of conventional spin glasses. Optical measurements in the ultraviolet to visible frequency range in a diffuse reflectance geometry indicate an overall optical band gap of 0.8 eV, consistent with observed semiconducting properties.

Systemic model for the aid for operating of the reactor Siloe

International Nuclear Information System (INIS)

Royer, J.C.; Moulin, V.; Monge, F.

1995-01-01

The Service of the Reactor Siloe (CEA/DRN/DRE/SRS), fully aware of the abilities and knowledge of his teams in the field of research reactor operating, has undertaken a project of knowledge engineering in this domain. The following aims have been defined: knowledge capitalization for the installation in order to insure its perenniality and valorization, elaboration of a project for the aid of the reactor operators. This article deals with the different actions by the SRS to reach the aims: realization of a technical model for the operation of the Siloe reactor, development of a knowledge-based system for the aid for operating. These actions based on a knowledge engineering methodology, SAGACE, and using industrial tools will lead to an amelioration of the security and the operating of the Siloe reactor. (authors). 13 refs., 7 figs

Updating systematic reviews: an international survey.

Directory of Open Access Journals (Sweden)

Chantelle Garritty

Full Text Available BACKGROUND: Systematic reviews (SRs should be up to date to maintain their importance in informing healthcare policy and practice. However, little guidance is available about when and how to update SRs. Moreover, the updating policies and practices of organizations that commission or produce SRs are unclear. METHODOLOGY/PRINCIPAL FINDINGS: The objective was to describe the updating practices and policies of agencies that sponsor or conduct SRs. An Internet-based survey was administered to a purposive non-random sample of 195 healthcare organizations within the international SR community. Survey results were analyzed using descriptive statistics. The completed response rate was 58% (n = 114 from across 26 countries with 70% (75/107 of participants identified as producers of SRs. Among responders, 79% (84/107 characterized the importance of updating as high or very-high and 57% (60/106 of organizations reported to have a formal policy for updating. However, only 29% (35/106 of organizations made reference to a written policy document. Several groups (62/105; 59% reported updating practices as irregular, and over half (53/103 of organizational respondents estimated that more than 50% of their respective SRs were likely out of date. Authors of the original SR (42/106; 40% were most often deemed responsible for ensuring SRs were current. Barriers to updating included resource constraints, reviewer motivation, lack of academic credit, and limited publishing formats. Most respondents (70/100; 70% indicated that they supported centralization of updating efforts across institutions or agencies. Furthermore, 84% (83/99 of respondents indicated they favoured the development of a central registry of SRs, analogous to efforts within the clinical trials community. CONCLUSIONS/SIGNIFICANCE: Most organizations that sponsor and/or carry out SRs consider updating important. Despite this recognition, updating practices are not regular, and many organizations lack

A prototype nuclear emergency response decision making expert system

International Nuclear Information System (INIS)

Chang, C.; Shih, C.; Hong, M.; Yu, W.; Su, M.; Wang, S.

1990-01-01

A prototype of emergency response expert system developed for nuclear power plants, has been fulfilled by Institute of Nuclear Energy Research. Key elements that have been implemented for emergency response include radioactive material dispersion assessment, dynamic transportation evacuation assessment, and meteorological parametric forecasting. A network system consists of five 80386 Personal Computers (PCs) has been installed to perform the system functions above. A further project is still continuing to achieve a more complicated and fanciful computer aid integral emergency response expert system

Administration of NaHS attenuates footshock-induced pathologies and emotional and cognitive dysfunction in triple transgenic Alzheimer’s mice

Directory of Open Access Journals (Sweden)

Hei-Jen eHuang

2015-11-01

Full Text Available Alzheimer's disease (AD is characterized by progressive cognitive decline and neuropsychiatric symptoms. Increasing evidence indicates that environmental risk factors in young adults may accelerate cognitive loss in AD and that hydrogen sulfide (H2S may represent an innovative treatment to slow the progression of AD. Therefore, the aim of this study was to evaluate the effects of NaHS, an H2S donor, in a triple transgenic AD mouse model (3×Tg-AD under footshock with situational reminders (SRs. Inescapable footshock with SRs induced anxiety and cognitive dysfunction as well as a decrease in the levels of plasma H2S and GSH and an increase in IL-6 levels in 3×Tg-AD mice. Under footshock with SR stimulus, amyloid deposition, tau protein hyperphosphorylation, and microgliosis were highly increased in the stress-responsive brain structures, including the hippocampus and amygdala, of the AD mice. Oxidative stress, inflammatory response, and β-site APP cleaving enzyme 1 (BACE1 levels were also increased, and the level of inactivated glycogen synthase kinase-3β (GSK3β (pSer9 was decreased in the hippocampi of AD mice subjected to footshock with SRs. Furthermore, the numbers of cholinergic neurons in the medial septum/diagonal band of Broca (MS/DB and noradrenergic neurons in the locus coeruleus (LC were also decreased in the 3×Tg-AD mice under footshock with SRs. These biochemical hallmarks and pathological presentations were all alleviated by the semi-acute administration of NaHS in the AD mice. Together, these findings suggest that footshock with SRs induces the impairment of spatial cognition and emotion, which involve pathological changes in the peripheral and central systems, including the hippocampus, MS/DB, LC, and BLA, and that the administration of NaHS may be a candidate strategy to ameliorate the progression of neurodegeneration.

Application of Prognostic Mesoscale Modeling in the Southeast United States

International Nuclear Information System (INIS)

Buckley, R.L.

1999-01-01

A prognostic model is being used to provide regional forecasts for a variety of applications at the Savannah River Site (SRS). Emergency response dispersion models available at SRS use the space and time-dependent meteorological data provided by this model to supplement local and regional observations. Output from the model is also used locally to aid in forecasting at SRS, and regionally in providing forecasts of the potential time and location of hurricane landfall within the southeast United States

Systemic Inflammatory Response and Adhesion Molecules

Directory of Open Access Journals (Sweden)

L. V. Molchanova

2005-01-01

Full Text Available The lecture presents the materials of foreign studies on the mechanisms responsible for the formation of a systemic inflammatory response syndrome (SIRS. The hypotheses accounting for the occurrence of SIRS in emergencies are described. Adhesion molecules (AM and endothelial dysfunction are apparent to be involved in the inflammatory process, no matter what the causes of SIRS are. The current classification of AM and adhesion cascades with altered blood flow is presented. There are two lines in the studies of AM. One line is to measure the concentration of AM in the plasma of patients with emergencies of various etiology. The other is to study the impact of antiadhesion therapy on the alleviation of the severity of terminal state and its outcome. The studies provide evidence for that an adhesive process is a peculiar prelude to a systemic inflammatory response.

Zero Suppression with Scalable Readout System (SRS) and APV25 FE Chip

CERN Document Server

Goentoro, Steven Lukas

2015-01-01

Zero suppression is a very useful algorithm in data acquisition and transfer. In this report, I would like to present the basic procedures of the application of Zero Suppression in the ordinary DAQ system that we have ( Date and Amore)

Retinal progenitor cell xenografts to the pig retina

DEFF Research Database (Denmark)

Warfvinge, Karin; Kiilgaard, Jens Folke; Klassen, Henry

2006-01-01

We evaluated the host response to murine retinal progenitor cells (RPCs) following transplantation to the subretinal space (SRS) of the pig. RPCs from GFP mice were transplanted subretinally in 18 nonimmunosuppressed normal or laser-treated pigs. Evaluation of the SRS was performed on hematoxylin-eosin...

Effectiveness of the Respiratory Gating System for Stereotectic Radiosurgery of Lung Cancer

Energy Technology Data Exchange (ETDEWEB)

Song, Heung Kwon; Kwon, Kyung Tae; Park, Cheol Su; Yang, Oh Nam; Kim, Min Su; Kim, Jeong Man [Dept. of Radiation Oncology, Asan Medical Center, Seoul (Korea, Republic of)

2005-09-15

For stereotactic radiosurgery (SRS) of a tumor in the region whose movement due to respiration is significant, like Lung lower lobe, the gated therapy, which delivers radiation dose to the selected respiratory phases when tumor motion is small, was performed using the Respiratory gating system and its clinical effectiveness was evaluated. For two SRS patients with a tumor in Lung lower lobe, a marker block (infrared reflector) was attached on the abdomen. While patient' respiratory cycle was monitored with Real-time Position Management (RPM, Varian, USA), 4D CT was performed (10 phases per a cycle). Phases in which tumor motion did not change rapidly were decided as treatment phases. The treatment volume was contoured on the CT images for selected treatment phases using maximum intensity projection (MIP) method. In order to verify setup reproducibility and positional variation, 4D CT was repeated. Gross tumor volume (GTV) showed maximum movement in superior-inferior direction. For patient no 1, motion of GTV was reduced to 2.6 mm in treatment phases (30-60%), while that was 9.4 mm in full phases (0-90%) and for patient no 2, it was reduced to 2.3 mm in treatment phases (30-70%), while it was 11.7 mm in full phases (0-90%). When comparing two sets of CT images, setup errors in all the directions were within 3 mm. Since tumor motion was reduced less than 5 mm, the Respiratory gating system for SRS of Lung lower lobe is useful.

Systems biology of neutrophil differentiation and immune response

DEFF Research Database (Denmark)

Theilgaard-Mönch, Kim; Porse, Bo T; Borregaard, Niels

2005-01-01

Systems biology has emerged as a new scientific field, which aims at investigating biological processes at the genomic and proteomic levels. Recent studies have unravelled aspects of neutrophil differentiation and immune responses at the systems level using high-throughput technologies. These stu......Systems biology has emerged as a new scientific field, which aims at investigating biological processes at the genomic and proteomic levels. Recent studies have unravelled aspects of neutrophil differentiation and immune responses at the systems level using high-throughput technologies....... These studies have identified a plethora of novel effector proteins stored in the granules of neutrophils. In addition, these studies provide evidence that neutrophil differentiation and immune response are governed by a highly coordinated transcriptional programme that regulates cellular fate and function...

Remote video radioactive systems evaluation, Savannah River Site

International Nuclear Information System (INIS)

Heckendorn, F.M.; Robinson, C.W.

1991-01-01

Specialized miniature low cost video equipment has been effectively used in a number of remote, radioactive, and contaminated environments at the Savannah River Site (SRS). The equipment and related techniques have reduced the potential for personnel exposure to both radiation and physical hazards. The valuable process information thus provided would not have otherwise been available for use in improving the quality of operation at SRS

Time response for sensor sensed to actuator response for mobile robotic system

Science.gov (United States)

Amir, N. S.; Shafie, A. A.

2017-11-01

Time and performance of a mobile robot are very important in completing the tasks given to achieve its ultimate goal. Tasks may need to be done within a time constraint to ensure smooth operation of a mobile robot and can result in better performance. The main purpose of this research was to improve the performance of a mobile robot so that it can complete the tasks given within time constraint. The problem that is needed to be solved is to minimize the time interval between sensor detection and actuator response. The research objective is to analyse the real time operating system performance of sensors and actuators on one microcontroller and on two microcontroller for a mobile robot. The task for a mobile robot for this research is line following with an obstacle avoidance. Three runs will be carried out for the task and the time between the sensors senses to the actuator responses were recorded. Overall, the results show that two microcontroller system have better response time compared to the one microcontroller system. For this research, the average difference of response time is very important to improve the internal performance between the occurrence of a task, sensors detection, decision making and actuator response of a mobile robot. This research helped to develop a mobile robot with a better performance and can complete task within the time constraint.

Ion-Responsive Drug Delivery Systems.

Science.gov (United States)

Yoshida, Takayuki; Shakushiro, Kohsuke; Sako, Kazuhiro

2018-02-08

Some kinds of cations and anions are contained in body fluids such as blood, interstitial fluid, gastrointestinal juice, and tears at relatively high concentration. Ionresponsive drug delivery is available to design the unique dosage formulations which provide optimized drug therapy with effective, safe and convenient dosing of drugs. The objective of the present review was to collect, summarize, and categorize recent research findings on ion-responsive drug delivery systems. Ions in body fluid/formulations caused structural changes of polymers/molecules contained in the formulations, allow formulations exhibit functions. The polymers/molecules responding to ions were ion-exchange resins/fibers, anionic or cationic polymers, polymers exhibiting transition at lower critical solution temperature, self-assemble supramolecular systems, peptides, and metalorganic frameworks. The functions of ion-responsive drug delivery systems were categorized to controlled drug release, site-specific drug release, in situ gelation, prolonged retention at the target sites, and enhancement of drug permeation. Administration of the formulations via oral, ophthalmic, transdermal, and nasal routes has showed significant advantages in the recent literatures. Many kinds of drug delivery systems responding to ions have been reported recently for several administration routes. Improvement and advancement of these systems can maximize drugs potential and contribute to patients in the world. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Poster - 44: Development and implementation of a comprehensive end-to-end testing methodology for linac-based frameless SRS QA using a modified commercial stereotactic anthropomorphic phantom

Energy Technology Data Exchange (ETDEWEB)

Liu, Derek; Mutanga, Theodore [University of Toronto, Carlo Fidani Peel Regional Cancer Center (Canada)

2016-08-15

Purpose: An end-to-end testing methodology was designed to evaluate the overall SRS treatment fidelity, incorporating all steps in the linac-based frameless radiosurgery treatment delivery process. The study details our commissioning experience of the Steev (CIRS, Norfolk, VA) stereotactic anthropomorphic head phantom including modification, test design, and baseline measurements. Methods: Repeated MR and CT scans were performed with interchanging inserts. MR-CT fusion accuracy was evaluated and the insert spatial coincidence was verified on CT. Five non-coplanar arcs delivered a prescription dose to a 15 mm spherical CTV with 2 mm PTV margin. Following setup, CBCT-based shifts were applied as per protocol. Sequential measurements were performed by interchanging inserts without disturbing the setup. Spatial and dosimetric accuracy was assessed by a combination of CBCT hidden target, radiochromic film, and ion chamber measurements. To facilitate film registration, the film insert was modified in-house by etching marks. Results: MR fusion error and insert spatial coincidences were within 0.3 mm. Both CBCT and film measurements showed spatial displacements of 1.0 mm in similar directions. Both coronal and sagittal films reported 2.3 % higher target dose relative to the treatment plan. The corrected ion chamber measurement was similarly greater by 1.0 %. The 3 %/2 mm gamma pass rate was 99% for both films Conclusions: A comprehensive end-to-end testing methodology was implemented for our SRS QA program. The Steev phantom enabled realistic evaluation of the entire treatment process. Overall spatial and dosimetric accuracy of the delivery were 1 mm and 3 % respectively.

Fire Department Emergency Response

International Nuclear Information System (INIS)

Blanchard, A.; Bell, K.; Kelly, J.; Hudson, J.

1997-09-01

In 1995 the SRS Fire Department published the initial Operations Basis Document (OBD). This document was one of the first of its kind in the DOE complex and was widely distributed and reviewed. This plan described a multi-mission Fire Department which provided fire, emergency medical, hazardous material spill, and technical rescue services

Analysis of soil and water at the Four Mile Creek seepline near the F ampersand H Areas of SRS

International Nuclear Information System (INIS)

Haselow, J.S.; Harris, M.; Looney, B.B.; Halverson, N.V.; Gladden, J.B.

1990-01-01

Until 1988, solutions containing sodium hydroxide, nitride acid, low levels of radionuclides (mostly tritiated water) and some metals were discharged to unlined seepage basins at the F and H Areas of the Savannah River Site (SRS) as part of normal operations (Killian et al, 1987a,b). The basins are now being closed according to the Resource Conservation and Recovery Act (RCRA). As part of the closure, a Part B Post-Closure Care Permit is being prepared. The information included in this report will fulfill some of the data requirements for that Part B permit. Several soil and water samples were collected along the Four Mile Creek (FMC) seepline at the F ampersand H Areas of the Savannah River Site. The samples were analyzed for concentrations of metals, radionuclides, and inorganic constituents. The goal of the work reported herein is to document the impacts from the basins of FMC has been completed in a phased approach

The Design and Implementation of the Ariel Active Database Rule System

Science.gov (United States)

1991-10-01

but only as a main-memory prototype. The POSTGRES rule system (PRS) [SHP88, SRH90] and the Starburst rule system (SRS) [WCL91, HCL+90] have been...query language of POSTGRES for specifying data definition commands, queries and updates [SRH90]. POSTQUEL commands retrieve, append, delete, and replace...placed on an arbitrary attribute (e.g., one without an index) ( POSTGRES rule system [SHP88, SHP89, SR1I90], HiPAC [C+891, DIPS [SLR89], Alert [SPAM91

Classroom Response System (CRS) pilot ‘Responsiveness and meaning for all’

NARCIS (Netherlands)

Rusman, Ellen; Ternier, Stefaan

2014-01-01

Classroom Response Systems (CRS or “clickers”) enable teachers and learners to get an insight in how well learners have understood and learnt from learning activities that they carried out, and to what degree they achieved certain learning objectives. With a CRS system, a teacher can pose a

Parametric Control on Fractional-Order Response for Lü Chaotic System

KAUST Repository

Moaddy, K; Radwan, A G; Salama, Khaled N.; Momani, S; Hashim, I

2013-01-01

This paper discusses the influence of the fractional order parameter on conventional chaotic systems. These fractional-order parameters increase the system degree of freedom allowing it to enter new domains and thus it can be used as a control for such dynamical systems. This paper investigates the behaviour of the equally-fractional-order Lü chaotic system when changing the fractional-order parameter and determines the fractional-order ranges for chaotic behaviour. Five different parameter values and six fractional-order cases are discussed through this paper. Unlike the conventional parameters, as the fractional-order increases the system response begins with stability, passing by chaotic behaviour then reaches periodic response. As the system parameter α increases, a shift in the fractional order is required to maintain chaotic response.Therefore, the range of chaotic response can be expanded or minimized by controlling the fractional-order parameter. The non-standard finite difference method is used to solve the fractional-order Lü chaotic system numerically to validate these responses.

Parametric Control on Fractional-Order Response for Lü Chaotic System

KAUST Repository

Moaddy, K

2013-04-10

This paper discusses the influence of the fractional order parameter on conventional chaotic systems. These fractional-order parameters increase the system degree of freedom allowing it to enter new domains and thus it can be used as a control for such dynamical systems. This paper investigates the behaviour of the equally-fractional-order Lü chaotic system when changing the fractional-order parameter and determines the fractional-order ranges for chaotic behaviour. Five different parameter values and six fractional-order cases are discussed through this paper. Unlike the conventional parameters, as the fractional-order increases the system response begins with stability, passing by chaotic behaviour then reaches periodic response. As the system parameter α increases, a shift in the fractional order is required to maintain chaotic response.Therefore, the range of chaotic response can be expanded or minimized by controlling the fractional-order parameter. The non-standard finite difference method is used to solve the fractional-order Lü chaotic system numerically to validate these responses.

1998 Annual Status Report: Submersed and Floating-Leaf Vegetation in Pools 4, 8, 13, and 26 and La Grange Pool of the Upper Mississippi River System

National Research Council Canada - National Science Library

Yin, Yao

2001-01-01

Aquatic vegetation was investigated in five navigation pools in the Upper Mississippi River System using a new protocol named 'stratified random sampling' or SRS protocol for the first time in 1998...

External-stimuli responsive systems for cancer theranostic

Directory of Open Access Journals (Sweden)

Jianhui Yao

2016-10-01

Full Text Available The upsurge of novel nanomaterials and nanotechnologies has inspired the researchers who are striving for designing safer and more efficient drug delivery systems for cancer therapy. Stimuli responsive nanomaterial offered an alternative to design controllable drug delivery system on account of its spatiotemporally controllable properties. Additionally, external stimuli (light, magnetic field and ultrasound could develop into theranostic applications for personalized medicine use because of their unique characteristics. In this review, we give a brief overview about the significant progresses and challenges of certain external-stimuli responsive systems that have been extensively investigated in drug delivery and theranostics within the last few years.

The impulsive control synchronization of the drive-response complex system

International Nuclear Information System (INIS)

Zhao Yanhong; Yang Yongqing

2008-01-01

This Letter investigates projective synchronization between the drive system and response complex dynamical system. An impulsive control scheme is adapted to synchronize the drive-response dynamical system to a desired scalar factor. By using the stability theory of the impulsive differential equation, the criteria for the projective synchronization are derived. The feasibility of the impulsive control of the projective synchronization is demonstrated in the drive-response dynamical system

Modular telerobot control system for accident response

Science.gov (United States)

Anderson, Richard J. M.; Shirey, David L.

1999-08-01

The Accident Response Mobile Manipulator System (ARMMS) is a teleoperated emergency response vehicle that deploys two hydraulic manipulators, five cameras, and an array of sensors to the scene of an incident. It is operated from a remote base station that can be situated up to four kilometers away from the site. Recently, a modular telerobot control architecture called SMART was applied to ARMMS to improve the precision, safety, and operability of the manipulators on board. Using SMART, a prototype manipulator control system was developed in a couple of days, and an integrated working system was demonstrated within a couple of months. New capabilities such as camera-frame teleoperation, autonomous tool changeout and dual manipulator control have been incorporated. The final system incorporates twenty-two separate modules and implements seven different behavior modes. This paper describes the integration of SMART into the ARMMS system.

Anxiety Disorders in Typically Developing Youth: Autism Spectrum Symptoms as a Predictor of Cognitive-Behavioral Treatment

Science.gov (United States)

Puleo, Connor M.; Kendall, Philip C.

2011-01-01

Symptoms of autism spectrum disorder (ASD) were assessed (Social Responsiveness Scale-Parent (SRS-P); coded in-session behavior) in typically-developing, anxiety-disordered children (N = 50) treated with cognitive-behavioral therapy (CBT). "Study 1": children with moderate autistic symptomology (per SRS-P) were significantly more likely to improve…

The Empathizing-Systemizing Theory, Social Abilities, and Mathematical Achievement in Children.

Science.gov (United States)

Escovar, Emily; Rosenberg-Lee, Miriam; Uddin, Lucina Q; Menon, Vinod

2016-03-14

The Empathizing-Systemizing (E-S) theory describes a profile of traits that have been linked to autism spectrum disorders, and are thought to encompass a continuum that includes typically developing (TD) individuals. Although systemizing is hypothesized to be related to mathematical abilities, empirical support for this relationship is lacking. We examine the link between empathizing and systemizing tendencies and mathematical achievement in 112 TD children (57 girls) to elucidate how socio-cognitive constructs influence early development of mathematical skills. Assessment of mathematical achievement included standardized tests designed to examine calculation skills and conceptual mathematical reasoning. Empathizing and systemizing were assessed using the Combined Empathy Quotient-Child (EQ-C) and Systemizing Quotient-Child (SQ-C). Contrary to our hypothesis, we found that mathematical achievement was not related to systemizing or the discrepancy between systemizing and empathizing. Surprisingly, children with higher empathy demonstrated lower calculation skills. Further analysis using the Social Responsiveness Scale (SRS) revealed that the relationship between EQ-C and mathematical achievement was mediated by social ability rather than autistic behaviors. Finally, social awareness was found to play a differential role in mediating the relationship between EQ-C and mathematical achievement in girls. These results identify empathy, and social skills more generally, as previously unknown predictors of mathematical achievement.

Waste Tank Corrosion Program at Savannah River Site

International Nuclear Information System (INIS)

Chandler, J.R.; Hsu, T.C.; Hobbs, D.T.; Iyer, N.C.; Marra, J.E.; Zapp, P.E.

1993-01-01

The Savannah River Site (SRS) has approximately 30 million gallons of high level radioactive waste stored in 51 underground tanks. SRS has maintained an active corrosion research and corrosion control and monitoring program throughout the operating history of SRS nuclear waste storage tanks. This program is largely responsible for the successful waste storage experience at SRS. The program has consisted of extensive monitoring of the tanks and surrounding environment for evidence of leaks, extensive research to understand the potential corrosion processes, and development and implementation of corrosion chemistry control. Current issues associated with waste tank corrosion are primarily focused on waste processing operations and are being addressed by a number of active programs and initiatives

Update to agency for toxic substances and disease registry 2012 report on assessment of biota exposure to mercury originating from Savannah River Site.

Energy Technology Data Exchange (ETDEWEB)

Kuhne, W. [Savannah River Site (SRS), Aiken, SC (United States)

2015-08-10

The purpose of this report is to 1) update previous Savannah River National Laboratory (SRNL) assessment reports (Kvartek et al. 1994 and Halverson et al. 2008) on the fate of mercury in the Savannah River Site (SRS) environment and 2) address comments and recommendations from the review of SRS by the Agency for Toxic Substances and Disease Registry (ATSDR) concerning the evaluation of exposures to contaminants in biota originating from the SRS. The ATSDR reviewed and evaluated data from SRS, South Carolina Department of Health & Environmental Control (SCDHEC) and the Georgia Department of Natural Resources (GDNR) concerning the non-radioactive contaminant mercury. This report will provide a response and update to conclusions and recommendations made by the ATSDR.

Non-destructive visualization of linear explosive-induced Pyroshock using phase arrayed laser-induced shock in a space launcher composite

International Nuclear Information System (INIS)

Jang, Jae Kyeong; Lee, Jung Ryul

2015-01-01

Separation mechanism of Space launch vehicles are used in various separation systems and pyrotechnic devices. The operation of these pyrotechnic devices generates Pyroshock that can cause failures in electronic components. The prediction of high frequency structural response, especially the shock response spectrum (SRS), is important. This paper presents a non-destructive visualization and simulation of linear explosive-induced Pyroshock using phase arrayed Laser-induced shock. The proposed method includes a laser shock test based on laser beam and filtering zone conditioning to predict the SRS of Pyroshock. A ballistic test based on linear explosive and non-contact Laser Doppler Vibrometers and a nondestructive Laser shock measurement using laser excitation and several PZT sensors, are performed using a carbon composite sandwich panel. The similarity of the SRS of the conditioned laser shock to that of the real explosive Pyroshock is evaluated with the Mean Acceleration Difference. The average of MADs over the two training points was 33.64%. And, MAD at verification point was improved to 31.99%. After that, experimentally found optimal conditions are applied to any arbitrary points in laser scanning area. Finally, it is shown that linear explosive-induced real Pyroshock wave propagation can be visualized with high similarity based on the proposed laser technology. (paper)

心理的健康に対するポジティブイリュージョンとセルフモニタリングの効果

OpenAIRE

石原, 俊一

2011-01-01

The purpose of the present research was to examine the effect of positive illusion, self-monitoring, and self-affirmation on the psychological stress responses of contemporary university students. Two hundred and two university students (82 males, 120 females) completed questionnaires based on a positive illusion scale, revised self-monitoring scale, self-affirmation scale, and stress response scale (SRS)-18.Path analysis of positive illusion, self-monitoring, self-affirmation, and SRS-18 was...

Social responsibility as a management system

Directory of Open Access Journals (Sweden)

Nuria Arimany-Serrat

2018-02-01

Originality/value: The study identifies a business management system that continuously organises and improves the performances of a company in the area of Corporate Social Responsibility, through audited certification that enhances the competitivity of companies that hold the international standard. The study also demonstrates the need for a management system to integrate into business models.

The national response system: Where do we go from here?

International Nuclear Information System (INIS)

Johnson, R.C.

1993-01-01

The response to the Exxon Valdez incident showed that the nation needs to be better prepared to respond to a spill of that magnitude. In research conducted on the Valdez response, several inadequacies were noted in the National Response System (NRS). A key deficiency identified was the critical need for a standardized management system to direct the response effort more effectively and efficiently. The most pressing question for preparedness planners in improving the NRS is open-quotes where do we go from here?close quotes. In answering this question, planners must address another question, open-quotes how long is it going to take?close quotes. There has been wide spread failure to put existing knowledge into practice. To fill the management void identified in the NRS, it is imperative that a response management system be adopted as soon as possible. Once adopted, it can be modified and refined to provide a more effective response. The system proposed in this paper uses the sound management practices of an incident command system and modifies and/or expands these practices to fit onto the foundation built by the NRS. This response management system could be used for all spills from minor ones to large, catastrophic spills of national significance (SONS)

Transformation Planning of Ecotourism Systems to Invigorate Responsible Tourism

Directory of Open Access Journals (Sweden)

Yun Eui Choi

2017-12-01

Full Text Available The purpose of this study is to introduce transformation plans that can stimulate responsible ecotourism by using systems thinking to solve ecotourism problems in Korea. Systems thinking is a research method used to understand the operating mechanisms of the variables that influence an entire system, in order to identify its problems. The four types of ecotourism systems are classified as follows: low-infrastructure and resident-initiated, high-infrastructure and resident-initiated, high-infrastructure and government-initiated and low-infrastructure and government-initiated. These systems vary based on the need for tourism facilities and the form of governance. Each type of system is analyzed using the systems thinking process (dynamic thinking, causal thinking, feedback thinking, strategic thinking at representative ecotourism sites in Jeollanam-do and the following transformation plans are proposed to improve the responsibility at the tourism sites: First, local residents will develop a system to manage and operate ecotourism ventures and establish cooperative governance structures to strengthen the local capacity. Second, ecotourism operators will improve the quality of their educational and interpretative programs and tourist information platforms in order to raise awareness of the responsibilities of ecotourists. Third, ecotourism systems that are improved through ecotourists’ and tour operators' heightened senses of responsibility can sustain ecotourism independently. These transformation plans can be applied to policy proposals for revitalizing ecotourism, to guidelines for improving community resilience and to biological habitat protection plans. This study is meaningful in that it discusses the role of stakeholders in ecotourism planning and promoting responsible tourism and their role in utilizing and conserving natural resources accordingly.