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Sample records for response spectrum analysis

  1. Response spectrum analysis of a stochastic seismic model

    International Nuclear Information System (INIS)

    Kimura, Koji; Sakata, Masaru; Takemoto, Shinichiro.

    1990-01-01

    The stochastic response spectrum approach is presented for predicting the dynamic behavior of structures to earthquake excitation expressed by a random process, one of whose sample functions can be regarded as a recorded strong-motion earthquake accelerogram. The approach consists of modeling recorded ground motion by a random process and the root-mean-square response (rms) analysis of a single-degree-of-freedom system by using the moment equations method. The stochastic response spectrum is obtained as a plot of the maximum rms response versus the natural period of the system and is compared with the conventional response spectrum. (author)

  2. Response spectrum analysis for multi-supported subsystems

    International Nuclear Information System (INIS)

    Reed, J.W.

    1983-01-01

    A methodology was developed to analyze multi-supported subsystems (e.g., piping systems) for seismic or other dynamic forces using response spectrum input. Currently, subsystems which are supported at more than one location in a nuclear power plant building are analyzed either by the time-history method or by response spectrum procedures, where spectra which envelop all support locations are used. The former procedure is exceedingly expensive, while the latter procedure is inexpensive but very conservative. Improved analysis procedures are currently being developed which are either coupled- or uncoupled-system approaches. For the coupled-system approach, response feedback between the subsystem and building system is included. For the uncoupled-system approach, feedback is neglected; however, either time history or response spectrum methods can be used. The methodology developed for analyzing multi-supported subsystems is based on the assumption that the building response and the subsystem response are uncoupled. This is the same assumption implicitly made by analysts who design singly-supported subsystems using floor response spectrum input. This approach implies that there is no response feedback between the primary building system and the subsystem, which is generally found to be conservative. The methodology developed for multi-supported subsystems makes this same assumption and thus should produce results with the same ease and degree of accuracy as results obtained for singly-supported subsystems. (orig./HP)

  3. A consistent response spectrum analysis including the resonance range

    International Nuclear Information System (INIS)

    Schmitz, D.; Simmchen, A.

    1983-01-01

    The report provides a complete consistent Response Spectrum Analysis for any component. The effect of supports with different excitation is taken into consideration, at is the description of the resonance ranges. It includes information explaining how the contributions of the eigenforms with higher eigenfrequencies are to be considered. Stocking of floor response spectra is also possible using the method described here. However, modified floor response spectra must now be calculated for each building mode. Once these have been prepared, the calculation of the dynamic component values is practically no more complicated than with the conventional, non-consistent methods. The consistent Response Spectrum Analysis can supply smaller and larger values than the conventional theory, a fact which can be demonstrated using simple examples. The report contains a consistent Response Spectrum Analysis (RSA), which, as far as we know, has been formulated in this way for the first time. A consistent RSA is so important because today this method is preferentially applied as an important tool for the earthquake proof of components in nuclear power plants. (orig./HP)

  4. Alternate modal combination methods in response spectrum analysis

    International Nuclear Information System (INIS)

    Wang, Y.K.; Bezler, P.

    1989-01-01

    In piping analyses using the response spectrum method Square Root of the Sum of the Squares (SRSS) with clustering between closely spaced modes is the combination procedure most commonly used to combine between the modal response components. This procedure is simple to apply and normally yields conservative estimates of the time history results. The purpose of this study is to investigate alternate methods to combine between the modal response components. These methods are mathematically based to properly account for the combination between rigid and flexible modal responses as well as closely spaced modes. The methods are those advanced by Gupta, Hadjian and Lindley-Yow to address rigid response modes and the Double Sum Combination (DSC) method and the Complete Quadratic Combination (CQC) method to account for closely spaced modes. A direct comparison between these methods as well as the SRSS procedure is made by using them to predict the response of six piping systems. For two piping systems thirty-three earthquake records were considered to account for the impact of variations in the characteristics of the excitation. The results provided by each method are compared to the corresponding time history estimates of results as well as to each other. The degree of conservatism associated with each method is characterized. 7 refs., 4 figs., 2 tabs

  5. Alternate modal combination methods in response spectrum analysis

    International Nuclear Information System (INIS)

    Bezler, P.; Curreri, J.R.; Wang, Y.K.; Gupta, A.K.

    1990-10-01

    In piping analyses using the response spectrum method Square Root of the Sum of the Squares (SRSS) with clustering between closely spaced modes is the combination procedure most commonly used to combine between the modal response components. This procedure is simple to apply and normally yields conservative estimates of the time history results. The purpose of this study is to investigate alternate methods to combine between the modal response components. These methods are mathematically based to properly account for the combination between rigid and flexible modal responses as well as closely spaced modes. The methods are those advanced by Gupta, Hadjian and Lindely-Yow to address rigid response modes and the Double Sum Combination (DSC) method and the Complete Quadratic Combination (CQC) method to account for closely spaced modes. A direct comparison between these methods as well as the SRSS procedure is made by using them to predict the response of six piping systems. The results provided by each method are compared to the corresponding time history estimates of results as well as to each other. The degree of conservatism associated with each method is characterized. 19 refs., 16 figs., 10 tabs

  6. Response spectrum analysis of coupled structural response to a three component seismic disturbance

    International Nuclear Information System (INIS)

    Boulet, J.A.M.; Carley, T.G.

    1977-01-01

    The work discussed herein is a comparison and evaluation of several response spectrum analysis (RSA) techniques as applied to the same structural model with seismic excitation having three spatial components. Lagrange's equations of motion for the system were written in matrix form and uncoupled with the modal matrix. Numerical integration (fourth order Runge-Kutta) of the resulting model equations produced time histories of system displacements in response to simultaneous application of three orthogonal components of ground motion, and displacement response spectra for each modal coordinate in response to each of the three ground motion components. Five different RSA techniques were used to combine the spectral displacements and the modal matrix to give approximations of maximum system displacements. These approximations were then compared with the maximum system displacements taken from the time histories. The RSA techniques used are the method of absolute sums, the square root of the sum of the squares, the double sum approach, the method of closely spaced modes, and Lin's method. The vectors of maximum system displacements as computed by the time history analysis and the five response spectrum analysis methods are presented. (Auth.)

  7. Coupled response spectrum analysis of secondary systems using uncoupled modal properties

    International Nuclear Information System (INIS)

    Gupta, A.K.; Jaw Jingwen

    1986-01-01

    A method of performing coupled response spectrum analysis of secondary systems is presented. The response spectrum specified at the base of the primary system is used as the input. The complex coupled mode shapes along with frequencies and damping values are calculated using an efficient and accurate perturbation scheme. The new method is applied to a 2 DOF secondary system coupled with a 6 DOF secondary system. The masses and the stiffness of the secondary system are varied to get nine different cases. The coupled system is subjected to El Centro (S00E, 1940) ground motion. It is shown that the response values from the present method are in good agreement with those from the coupled time history analysis. The conventional floor response spectrum method gives response values which are consistently much higher than the corresponding values from the time history analysis. It is concluded that the present method is sufficiently straightforward and efficient, and that it yields accurate response values. (orig.)

  8. Response spectrum analysis of coupled structural response to a three component seismic disturbance

    International Nuclear Information System (INIS)

    Boulet, J.A.M.; Carley, T.G.

    1977-01-01

    The work discussed herein is a comparison and evaluation of several response spectrum analysis (RSA) techniques as applied to the same structural model with seismic excitation having three spatial components. The structural model includes five lumped masses (floors) connected by four elastic members. The base is supported by three translational springs and two horizontal torsional springs. In general, the mass center and shear center of a building floor are distinct locations. Hence, inertia forces, which act at the mass center, induce twisting in the structure. Through this induced torsion, the lateral (x and y) displacements of the mass elements are coupled. The ground motion components used for this study are artificial earthquake records generated from recorded accelerograms by a spectrum modification technique. The accelerograms have response spectra which are compatible with U.S. NRC Regulatory Guide 1.60. Lagrange's equations of motion for the system were written in matrix form and uncoupled with the modal matrix. Numerical integration (fourth order Runge-Kutta) of the resulting modal equations produced time histories of system displacements in response to simultaneous application of three orthogonal components of ground motion, and displacement response spectra for each modal coordinate in response to each of the three ground motion components. Five different RSA techniques were used to combine the spectral displacements and the modal matrix to give approximations of maximum system displacements. These approximations were then compared with the maximum system displacements taken from the time histories. The RSA techniques used are the method of absolute sums, the square root of the sum of the sum of the squares, the double sum approach, the method of closely spaced modes, and Lin's method

  9. Effect of PVRC damping with independent support motion response spectrum analysis of piping systems

    International Nuclear Information System (INIS)

    Wang, Y.K.; Bezler, P.; Shteyngart, S.

    1986-01-01

    The Technical Committee for Piping Systems of the Pressure Vessel Research Committee (PVRC) has recommended new damping values to be used in the seismic analyses of piping systems in nuclear power plants. To evaluate the effects of coupling these recommendations with the use of independent support motion analyses methods, two sets of seismic analyses have been carried out for several piping systems. One set based on the use of uniform damping as specified in Regulatory Guide 1.61, the other based on the PVRC recommendations. In each set the analyses were performed using independent support motion time history and response spectrum methods as well as the envelope spectrum method. In the independent response spectrum analyses, 14 response estimates were in fact obtained by considering different combination procedures between the support group contributions and all sequences of combinations between support groups, modes and directions. For each analysis set, the response spectrum results were compared with time history estimates of those results. Comparison tables were then prepared depicting the percentage by which the response spectrum estimates exceeded the time history estimates. By comparing the result tables between both analysis sets, the impact of PVRC damping can be observed. Preliminary results show that the degree of exceedance of the response spectrum estimates based on PVRC damping is less than that based on uniform damping for the same piping problem. Expressed differently the results obtained if ISM methods are coupled with PVRC damping are not as conservative as those obtained using uniform damping

  10. Simplified inelastic seismic response analysis of piping system using improved capacity spectrum method

    International Nuclear Information System (INIS)

    Iijima, Tadashi

    2005-01-01

    We applied improved capacity spectrum method (ICSM) to a piping system with an asymmetric load-deformation relationship in a piping elbow. The capacity spectrum method can predict an inelastic response by balancing the structural capacity obtained from the load-deformation relationship with the seismic demand defined by an acceleration-displacement response spectrum. The ICSM employs (1) effective damping ratio and period that are based on a statistical methodology, (2) practical procedures necessary to obtain a balance between the structural capacity and the seismic demand. The effective damping ratio and period are defined so as to maximize the probability that predicted response errors lie inside the -10 to 20% range. However, without taking asymmetry into consideration the displacement calculated by using the load-deformation relationship on the stiffer side was 39% larger than that of a time history analysis by a direct integral method. On the other hand, when asymmetry was taken into account, the calculated displacement was only 14% larger than that of a time history analysis. Thus, we verified that the ICSM could predict the inelastic response with errors lying within the -10 to 20% range, by taking into account the asymmetric load-deformation relationship of the piping system. (author)

  11. Prediction of Support Reaction Forces of ITA via Response Spectrum Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kwak, Jin Sung; Jeong, Joon Ho; Lee, Sang Jin; Oh, Jin Ho; Lee, Jong Min [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    The irradiation targets are transferred along pipes between TTS (Target Transfer Station) and ITA (Irradiation Tube Assembly) by hydraulic forces. The ITA corresponds to the vertical guide tube for irradiation targets inside a reactor, and it penetrates the reactor structure. Because the ITA is classified into seismic category II, its structural integrity must be evaluated by the seismic analysis. To approach more realistic problem, the interaction between the ITA and the reactor structure must be considered. However, this paper is focused on the preliminary analysis, and it is simplified that only the response of the ITA caused by earthquake affects the reactor structure. The response of the ITA is predicted by the spectrum response analysis based on the FDRS (Floor Design Response Spectra) of KJRR. Finally, the reaction forces corresponding to the load transfer into the reactor structure are estimated by using ANSYS. In this study, the reaction forces due to the earthquake are estimated by the response spectrum analysis. For the saving computational time and resource required, the FE model with beam element is constructed, and it is confirmed that the accuracy of the solution is acceptable by comparing the results of the solid model.

  12. Numerical study of the mode selection in response spectrum analysis-condensed version

    International Nuclear Information System (INIS)

    Ng, D.S.

    1986-01-01

    For quality assurance of the dynamic response spectrum analysis, the Nuclear Regulatory Commission (NRC) recommends retaining all modes below the cutoff frequency at which the spectral acceleration (S/sub a/) returns to the peak zero period acceleration (ZPA). It also suggests that modes accounting for at least 90 percent of the structural masses be included in the analysis. A simple frame-type structure is generated as a baseline frame. Then groups of oscillators representing substructure are added onto the frame to study substructure behavior. A base case is established for each frame by including the specific number of modes used. The tests are conducted by incrementing the number of modes in the response spectrum analyses starting with one mode. The structural response of each modal increment is compared with the base case to identify the efficiency of mode selection method. All three methods are then applied to the MFTF-B Axicell Vacuum Vessel. The responses in critical components of the vessel, such as hangers and foundations, will be analyzed to confirm the accuracy of the selected method

  13. Efficient response spectrum analysis of a reactor using Model Order Reduction

    International Nuclear Information System (INIS)

    Oh, Jin Ho; Choi, Jin Bok; Ryu, Jeong Soo

    2012-01-01

    A response spectrum analysis (RSA) has been widely used to evaluate the structural integrity of various structural components in the nuclear industry. However, solving the large and complex structural systems numerically using the RSA requires a considerable amount of computational resources and time. To overcome this problem, this paper proposes the RSA based on the model order reduction (MOR) technique achieved by applying a projection from a higher order to a lower order space using Krylov subspaces generated by the Arnoldi algorithm. The dynamic characteristics of the final reduced system are almost identical with those of the full system by matching the moments of the reduced system with those of the full system up to the required nth order. It is remarkably efficient in terms of computation time and does not require a global system. Numerical examples demonstrate that the proposed method saves computational costs effectively, and provides a reduced system framework that predicts the accurate responses of a global system

  14. Analysis of soil-structure interaction and floor response spectrum of reactor building for China advanced research reactor

    International Nuclear Information System (INIS)

    Rong Feng; Wang Jiachun; He Shuyan

    2006-01-01

    Analysis of Soil-Structure Interaction (SSI) and calculation of Floor Response Spectrum (FRS) is substantial for anti-seismic design for China Advanced Research Reactor (CARR) project. The article uses direct method to analyze the seismic reaction of the reactor building in considering soil-structure interaction by establishing two-dimensional soil-structure co-acting model for analyzing and inputting of seismic waves from three directions respectively. The seismic response and floor response spectrum of foundation and floors of the building under different cases have been calculated. (authors)

  15. A comparison of response spectrum and direct integration analysis methods as applied to a nuclear component support structure

    International Nuclear Information System (INIS)

    Bryan, B.J.; Flanders, H.E. Jr.

    1992-01-01

    Seismic qualification of Class I nuclear components is accomplished using a variety of analytical methods. This paper compares the results of time history dynamic analyses of a heat exchanger support structure using response spectrum and time history direct integration analysis methods. Dynamic analysis is performed on the detailed component models using the two methods. A nonlinear elastic model is used for both the response spectrum and direct integration methods. A nonlinear model which includes friction and nonlinear springs, is analyzed using time history input by direct integration. The loads from the three cases are compared

  16. Real time spectrum analysis

    International Nuclear Information System (INIS)

    Blunden, A.; O'Prey, D.G.; Tait, W.H.

    1983-01-01

    A method is described for the separation of a composite pulse-height spectrum into its unresolved component parts, which belong to a set of measured library spectra. The method allows real-time estimation giving running estimates during acquisition of the spectrum, minimises computation space, especially for a number of parallel calculations, estimates in advance the rms errors, and produces a significance measure for the hypothesis that the composite contains only the library spectra. Least squares curve-fitting, and other methods, can be compared, with the formalism developed, allowing analytical comparison of the effect of detector energy resolution and detection efficiency. A rational basis for the choice between the various methods of spectrum analysis follows from the theory, minimising rms estimation errors. The method described is applicable for very low numbers of counts and poor resolution. (orig.)

  17. Development of methodology and computer programs for the ground response spectrum and the probabilistic seismic hazard analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Joon Kyoung [Semyung Univ., Research Institute of Industrial Science and Technol , Jecheon (Korea, Republic of)

    1996-12-15

    Objective of this study is to investigate and develop the methodologies and corresponding computer codes, compatible to the domestic seismological and geological environments, for estimating ground response spectrum and probabilistic seismic hazard. Using the PSHA computer program, the Cumulative Probability Functions(CPDF) and Probability Functions (PDF) of the annual exceedence have been investigated for the analysis of the uncertainty space of the annual probability at ten interested seismic hazard levels (0.1 g to 0.99 g). The cumulative provability functions and provability functions of the annual exceedence have been also compared to those results from the different input parameter spaces.

  18. Reduced object related negativity response indicates impaired auditory scene analysis in adults with autistic spectrum disorder

    Directory of Open Access Journals (Sweden)

    Veema Lodhia

    2014-02-01

    Full Text Available Auditory Scene Analysis provides a useful framework for understanding atypical auditory perception in autism. Specifically, a failure to segregate the incoming acoustic energy into distinct auditory objects might explain the aversive reaction autistic individuals have to certain auditory stimuli or environments. Previous research with non-autistic participants has demonstrated the presence of an Object Related Negativity (ORN in the auditory event related potential that indexes pre-attentive processes associated with auditory scene analysis. Also evident is a later P400 component that is attention dependent and thought to be related to decision-making about auditory objects. We sought to determine whether there are differences between individuals with and without autism in the levels of processing indexed by these components. Electroencephalography (EEG was used to measure brain responses from a group of 16 autistic adults, and 16 age- and verbal-IQ-matched typically-developing adults. Auditory responses were elicited using lateralized dichotic pitch stimuli in which inter-aural timing differences create the illusory perception of a pitch that is spatially separated from a carrier noise stimulus. As in previous studies, control participants produced an ORN in response to the pitch stimuli. However, this component was significantly reduced in the participants with autism. In contrast, processing differences were not observed between the groups at the attention-dependent level (P400. These findings suggest that autistic individuals have difficulty segregating auditory stimuli into distinct auditory objects, and that this difficulty arises at an early pre-attentive level of processing.

  19. A simplified multisupport response spectrum method

    Science.gov (United States)

    Ye, Jihong; Zhang, Zhiqiang; Liu, Xianming

    2012-03-01

    A simplified multisupport response spectrum method is presented. The structural response is a sum of two components of a structure with a first natural period less than 2 s. The first component is the pseudostatic response caused by the inconsistent motions of the structural supports, and the second is the structural dynamic response to ground motion accelerations. This method is formally consistent with the classical response spectrum method, and the effects of multisupport excitation are considered for any modal response spectrum or modal superposition. If the seismic inputs at each support are the same, the support displacements caused by the pseudostatic response become rigid body displacements. The response spectrum in the case of multisupport excitations then reduces to that for uniform excitations. In other words, this multisupport response spectrum method is a modification and extension of the existing response spectrum method under uniform excitation. Moreover, most of the coherency coefficients in this formulation are simplified by approximating the ground motion excitation as white noise. The results indicate that this simplification can reduce the calculation time while maintaining accuracy. Furthermore, the internal forces obtained by the multisupport response spectrum method are compared with those produced by the traditional response spectrum method in two case studies of existing long-span structures. Because the effects of inconsistent support displacements are not considered in the traditional response spectrum method, the values of internal forces near the supports are underestimated. These regions are important potential failure points and deserve special attention in the seismic design of reticulated structures.

  20. 239pu alpha spectrum analysis based on PIPS detector response function and variations with vacuum and distance

    Institute of Scientific and Technical Information of China (English)

    Rui Shi; Xian-Guo Tuo; Huai-Liang Li; Jian-Bo Yang; Yi Cheng; Hong-Long Zheng

    2017-01-01

    Effect factors of the absorption of the source,air,entrance window,and dead layer of a detector must be considered in the measurement of monoenergetic alpha particles,along with statsfical noise and other factors that collectively cause the alpha spectrum to exhibit a well-known low-energy tail.Therefore,the establishment of an alpha spectrum detector response function from the perspective of a signaling system must consider the various factors mentioned above.The detector response function is the convolution of an alphaparticle pulse function,two exponential functions,and a Gaussian function,followed by calculation of the parameters of the detector response function using the weighted leastsquares fitting method as proposed in this paper.In our experiment,239pu alpha spectra were measured by a highresolution,passivated implanted planar silicon (PIPS)detector at 10 levels of vacuum and 10 source-detector distances.The spectrum-fitting results were excellent as evaluated by reduced Chi-square (x2) and correlation coefficients.Finally,the variation of parameters with vacuum level and source-detector distance was studied.Results demonstrate that ο,τ1,and τ2 exhibit no obvious trend of variation with vacuum in the range 2000-20,000 mTorr,and at a confidence level of 95%,the values of τ1 and τ2 decline in a similar fashion with source-detector distance by the power exponential function,while the value of ο declines linearly.

  1. Consideration of vertical seismic response spectrum in nuclear safety review

    International Nuclear Information System (INIS)

    Sun Zaozhan; Huang Bingchen

    2011-01-01

    The basic requirements for civil nuclear installation are introduced in the article. Starting from the basic concept of seismic response spectrum, the authors analyze the site seismic response spectrum and the design seismic response spectrum that desire much consideration. By distinguishing the absolute seismic response spectrum and relative seismic response spectrum, the authors analyze the difference and relationship between the vertical seismic response spectrum and horizontal seismic response spectrum. The authors also bring forward some suggestions for determining the site vertical seismic response spectrum by considering the fact in our country. (authors)

  2. Vertical Footbridge Vibrations: The Response Spectrum Methodology

    DEFF Research Database (Denmark)

    Georgakis, Christos; Ingólfsson, Einar Thór

    2008-01-01

    In this paper, a novel, accurate and readily codifiable methodology for the prediction of vertical footbridge response is presented. The methodology is based on the well-established response spectrum approach used in the majority of the world’s current seismic design codes of practice. The concept...... of a universally applicable reference response spectrum is introduced, from which the pedestrian-induced vertical response of any footbridge may be determined, based on a defined “event” and the probability of occurrence of that event. A series of Monte Carlo simulations are undertaken for the development...... period is introduced and its implication on the calculation of footbridge response is discussed. Finally, a brief comparison is made between the theoretically predicted pedestrian-induced vertical response of an 80m long RC footbridge (as an example) and actual field measurements. The comparison shows...

  3. Multiple Beta Spectrum Analysis Method Based on Spectrum Fitting

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Uk Jae; Jung, Yun Song; Kim, Hee Reyoung [UNIST, Ulsan (Korea, Republic of)

    2016-05-15

    When the sample of several mixed radioactive nuclides is measured, it is difficult to divide each nuclide due to the overlapping of spectrums. For this reason, simple mathematical analysis method for spectrum analysis of the mixed beta ray source has been studied. However, existing research was in need of more accurate spectral analysis method as it has a problem of accuracy. The study will describe the contents of the separation methods of the mixed beta ray source through the analysis of the beta spectrum slope based on the curve fitting to resolve the existing problem. The fitting methods including It was understood that sum of sine fitting method was the best one of such proposed methods as Fourier, polynomial, Gaussian and sum of sine to obtain equation for distribution of mixed beta spectrum. It was shown to be the most appropriate for the analysis of the spectrum with various ratios of mixed nuclides. It was thought that this method could be applied to rapid spectrum analysis of the mixed beta ray source.

  4. Analysis of alpha spectrum instrumental errors accounting for the low energy part of semiconductor detector response function

    International Nuclear Information System (INIS)

    Gurbich, A.F.

    1981-01-01

    A technique for processing of instrumental spectrum of charged particles permitting to take account of a low-energy part of spectrometer line shape, to improve accuracy and to estimate detection efficiency is stated on the example of 226 Ra alpha spectrum. The results obtained show that relative intensities of alpha lines within the limits of statistical errors coincide with the known values, line ''tails'' constituting to 3% of total area of the line. Taking account of ''the line tail'' results in shift of centers of peak gravity by 10-20 keV. So low-energy part of the alpha spectrometer line, which is usually not taken account during spectra processing, markedly affect the results [ru

  5. Comparison of LMFBR piping response obtained using response spectrum and time history methods

    International Nuclear Information System (INIS)

    Hulbert, G.M.

    1981-04-01

    The dynamic response to a seismic event is calculated for a piping system using a response spectrum analysis method and two time history analysis methods. The results from the analytical methods are compared to identify causes for the differences between the sets of analytical results. Comparative methods are also presented which help to gain confidence in the accuracy of the analytical methods in predicting piping system structure response during seismic events

  6. Presentation of an approach for the analysis of the mechanical response of propellant under a large spectrum of loadings: numerical and mechanical issues

    Science.gov (United States)

    Fanget, Alain

    2009-06-01

    Many authors claim that to understand the response of a propellant, specifically under quasi static and dynamic loading, the mesostructural morphology and the mechanical behaviour of each of its components have to be known. However the scale of the mechanical description of the behaviour of a propellant is relative to its heterogeneities and the wavelength of loading. The shorter it is, the more important the topological description of the material is. In our problems, involving the safety of energetic materials, the propellant can be subjected to a large spectrum of loadings. This presentation is divided into five parts. The first part describes the processes used to extract the information about the morphology of the meso-structure of the material and presents some results. The results, the difficulties and the perspectives for this part will be recalled. The second part determines the physical processes involved at this scale from experimental results. Taking into account the knowledge of the morphology, two ways have been chosen to describe the response of the material. One concerns the quasi static loading, the object of the third part, in which we show how we use the mesoscopic scale as a base of development to build constitutive models. The fourth part presents for low but dynamic loading the comparison between numerical analysis and experiments.

  7. Implicit Learning Abilities Predict Treatment Response in Autism Spectrum Disorders

    Science.gov (United States)

    2015-09-01

    early behavioral interventions are the most effective treatment for Autism Spectrum Disorder (ASD), but almost half of the children do not make...behavioral intervention . 2. KEYWORDS Autism Spectrum Disorder , implicit learning, associative learning, individual differences, functional Magnetic...2 AWARD NUMBER: W81XWH-14-1-0261 TITLE: Implicit Learning Abilities Predict Treatment Response in Autism Spectrum Disorders PRINCIPAL

  8. Analysis of biological spectrum of Divčibare flora

    Directory of Open Access Journals (Sweden)

    Popović Ivana

    2006-01-01

    Full Text Available One of the essential analyses which is performed during the floristic study of a region is the analysis of the biological spectrum. The analysis of the biological spectrum of the flora includes the determination of the type of life form for each taxon described in the flora of the study region. If it is considered that life form is a specific structural-functional response to the environmental effects and the result of the adaptation during the species evolution, it is clear that the basic characteristics of the site are more or less reflected in any life form. This fact is confirmed by the analysis of the biological spectrum of Divčibare flora. The study results are in correlation with the results of the analysis of the biological spectrum of the flora of Serbia and the Balkan Peninsula.

  9. Comparison study of time history and response spectrum responses for multiply supported piping systems

    International Nuclear Information System (INIS)

    Wang, Y.K.; Subudhi, M.; Bezler, P.

    1983-01-01

    In the past decade, several investigators have studied the problem of independent support excitation of a multiply supported piping system to identify the real need for such an analysis. This approach offers an increase in accuracy at a small increase in computational costs. To assess the method, studies based on the response spectrum approach using independent support motions for each group of commonly connected supports were performed. The results obtained from this approach were compared with the conventional envelope spectrum and time history solutions. The present study includes a mathematical formulation of the independent support motion analysis method suitable for implementation into an existing all purpose piping code PSAFE2 and a comparison of the solutions for some typical piping system using both Time History and Response Spectrum Methods. The results obtained from the Response Spectrum Methods represent the upper bound solution at most points in the piping system. Similarly, the Seismic Anchor Movement analysis based on the SRP method over predicts the responses near the support points and under predicts at points away from the supports

  10. An extensive study on a simple method estimating response spectrum based on a simulated spectrum

    International Nuclear Information System (INIS)

    Sato, H.; Komazaki, M.; Ohori, M.

    1977-01-01

    The basic description of the procedure will be briefly described in the paper. Corresponding to peaks of the response spectrum for the earthquake motion the component of the respective ground predominant period was taken. The acceleration amplification factor of a building structure for the respective predominant period above taken was obtained from the spectrum for the simulated earthquake with single predominant period. The rate of the respective component in summing these amplification factors was given by satisfying the ratio among the magnitude of the peaks of the spectrum. The summation was made by the principle of the square root of sum of squares. The procedure was easily applied to estimate the spectrum of the building appendage structure. The method is attempted to extend for multi-storey building structure and appendage to this building. Analysis is made as for a two storey structure system the mode of which for the first natural frequency is that the amplitude ratio of the upper mass to the lower is 2 to 1, so that the mode shape is a reversed triangle. The behavior of the system is dealt with by the normal coordinate. The amplification factors due to two ground predominant periods are estimated for the system with the first natural frequency. In this procedure the method developed for the single-degree-of-freedom system is directly applicable. The same method is used for the system with the second natural frequency. Thus estimated amplification factor for the mode of the respective natural frequency is summed again due to the principle of the square root of sum of squares after multiplying the excitation coefficient of each mode by the corresponding factor

  11. Generation of equipment response spectrum considering equipment-structure interaction

    International Nuclear Information System (INIS)

    Lee, Sang Hoon; Yoo, Kwang Hoon

    2005-01-01

    Floor response spectra for dynamic response of subsystem such as equipment, or piping in nuclear power plant are usually generated without considering dynamic interaction between main structure and subsystem. Since the dynamic structural response generally has the narrow-banded shapes, the resulting floor response spectra developed for various locations in the structure usually have high spectral peak amplitudes in the narrow frequency bands corresponding to the natural frequencies of the structural system. The application of such spectra for design of subsystems often leads to excessive design conservatisms, especially when the equipment frequency and structure are at resonance condition. Thus, in order to provide a rational and realistic design input for dynamic analysis and design of equipment, dynamic equipment-structure interaction (ESI) should be considered in developing equipment response spectrum which is particularly important for equipment at the resonance condition. Many analytical methods have been proposed in the past for developing equipment response spectra considering ESI. However, most of these methods have not been adapted to the practical applications because of either the complexities or the lack of rigorousness of the methods. At one hand, mass ratio among the equipment and structure was used as an important parameter to obtain equipment response spectra. Similarly, Tseng has also proposed the analytical method for developing equipment response spectra using mass ratio in the frequency domain. This method is analytically rigorous and can be easily validated. It is based on the dynamic substructuring method as applied to the dynamic soil-structure interaction (SSI) analysis, and can relatively easily be implemented for practical applications without to change the current dynamic analysis and design practice for subsystems. The equipment response spectra derived in this study are also based on Tseng's proposed method

  12. Gamma-Ray Spectrum Analysis Software GDA

    International Nuclear Information System (INIS)

    Wanabongse, P.

    1998-01-01

    The developmental work on computer software for gamma-ray spectrum analysis has been completed as a software package version 1.02 named GDA, which is an acronym for Gamma-spectrum Deconvolution and Analysis. The software package consists of three 3.5-inch diskettes for setup and a user's manual. GDA software can be installed for using on a personal computer with Windows 95 or Windows NT 4.0 operating system. A computer maybe the type of 80486 CPU with 8 megabytes of memory

  13. Instantaneous response spectrum in seismic testing of nuclear power plant equipment

    International Nuclear Information System (INIS)

    Morrone, A.

    1977-01-01

    Seismic response spectra, as used in seismic analyses, give the maximum responses of single degree of freedom oscillators without consideration of the different time in the seismic time history at which each of the maximum responses occur. For response spectrum seismic analysis, the use of time-independent maximum responses is appropriate. The time dependece is considered in a statistical manner, for multi-degree of freedom systems, usually by combining the modal effects by the square root of the sum of the squares. For seismic testing of electrical equipment. IEEE Std. 344-1975 makes use of the response spectrum to define the input motion of the shake table. One of the basic requirements is that the test response spectrum (TRS) that is, the response spectrum produced by the shake table motion, should envelop the required response spectrum (RRS) calculated from the building analysis at the support point of the equipment being tested. This paper presents the concept of instantaneous response spectrum (IRS) as the response of single degree of freedom oscillators at a particular time. It demonstrates that a shake table random motion whose standard TRS envelops the RRS does not necessarily satisfy the enveloping requirement instantaneously. (Auth.)

  14. Full spectrum analysis in environmental monitoring

    International Nuclear Information System (INIS)

    Reinhardt, Sascha; Hartmann, Soeren; Pimpl, Richard

    2015-01-01

    In the environmental monitoring spectroscopic gamma detectors are frequently used. The motivation to use spectroscopic gamma detectors is the higher sensitivity and specific spectral information. For the analysis often the photo peaks of the gamma spectrum are used to identify the nuclide. These methods are very reliable, robust and well developed but using only the photo peak means also to use only a fraction of the available information. Doing a full spectrum analysis based on principle components obtained from NASVD for description of the radiation background and adjustment calculations are a possible analysis method which may provide advantages compared to a peak based analysis when used for a continuous environmental monitoring. An analysis example is shown and discussed with a measured time series of gamma spectra obtained from a spectroscopic gamma detector SARA IGS710 with a NaI(Tl) scintillator as it is used in the environmental monitoring.

  15. Full spectrum analysis in environmental monitoring

    International Nuclear Information System (INIS)

    Reinahrdt, S.; Hartmann, S.; Pimpl, R.

    2014-01-01

    In the environmental monitoring spectroscopic gamma detectors are frequently used. The motivation to use spectroscopic gamma detectors is the higher sensitivity and specific spectral information. For the analysis often the photo peaks of the gamma spectrum are used to identify the nuclide. These methods are very reliable, robust and well developed but using only the photo peak means also to use only a fraction of the available information. Doing a full spectrum analysis based on principal components obtained from NASVD for description of the radiation background and adjustment calculations are a possible analysis method, which may provide advantages compared to a peak based analysis when used for a continuous environmental monitoring. An analysis example is shown and discussed with a measured time series of gamma spectra obtained from a spectroscopic gamma detector SARA IGS710 with a NaI(Tl) scintillator as it is used in the environmental monitoring. (authors)

  16. Nuclear spectrum analysis by using microcomputer

    International Nuclear Information System (INIS)

    Sanyal, M.K.; Mukhopadhyay, P.K.; Rao, A.D.; Pethe, V.A.

    1984-01-01

    A method is presented for analysis of nuclear spectra by using microcomputer. A nonlinear least square fit of a mathematical model with observed spectrum is performed with variable metric method. The linear search procedure of the variable metric method has been modified so that the algorithm needs less program space and computational time both of which are important for microcomputer implementation. This widely used peak analysis method can now be made available in microcomputer based multichannel analysers. (author)

  17. Evaluation of Floor Response Spectrum considering Ductility of Structure

    International Nuclear Information System (INIS)

    Park, Junhee; Choi, In-Kil

    2014-01-01

    The FRS (floor response spectrum) is directly influenced by the behavior of structure under the seismic load. If the structure is nonlinear range, the energy dissipation will be occurred by the damage of structure and the maximum force will be reduced. In Zion method, the inelastic energy abortion factor has been used to consider the nonlinearity of structure. This factor was used for the seismic fragility of structure. For the seismic fragility of equipment, the uncertainty of this factor was used differently according to the story level. But this method is not warranted under the strong earthquake leads to the structural damage. Therefore it is needed to evaluate the FRS considering the nonlinear behavior of structure and to assessment the conservatism related to nonlinear behavior of structure in FRS. In this study, the nonlinear analysis was performed for the conservatism of FRS under the damage of structure. The conservatism of FRS by the nonlinear analysis was compared by that proposed by the Zion method. The conservatism of floor acceleration response for the equipment was evaluated by performing the nonlinear analysis. From the nonlinear analysis results, it was showed that the median and β c of FRSR was increased with the ductility of structure and the response of equipment had the resonance effect between the frequency of equipment and structure. The seismic capacity of equipment by the Zion method can be different from the real seismic capacity of equipment because the inelastic structure response factor has nothing to do with the ductility of structure. Therefore the median and COV for FRSR should be defined considering the ductility of structure and the frequency of equipment for more exactly evaluating the seismic capacity of equipment

  18. Evaluation of Floor Response Spectrum considering Ductility of Structure

    Energy Technology Data Exchange (ETDEWEB)

    Park, Junhee; Choi, In-Kil [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-10-15

    The FRS (floor response spectrum) is directly influenced by the behavior of structure under the seismic load. If the structure is nonlinear range, the energy dissipation will be occurred by the damage of structure and the maximum force will be reduced. In Zion method, the inelastic energy abortion factor has been used to consider the nonlinearity of structure. This factor was used for the seismic fragility of structure. For the seismic fragility of equipment, the uncertainty of this factor was used differently according to the story level. But this method is not warranted under the strong earthquake leads to the structural damage. Therefore it is needed to evaluate the FRS considering the nonlinear behavior of structure and to assessment the conservatism related to nonlinear behavior of structure in FRS. In this study, the nonlinear analysis was performed for the conservatism of FRS under the damage of structure. The conservatism of FRS by the nonlinear analysis was compared by that proposed by the Zion method. The conservatism of floor acceleration response for the equipment was evaluated by performing the nonlinear analysis. From the nonlinear analysis results, it was showed that the median and β{sub c} of FRSR was increased with the ductility of structure and the response of equipment had the resonance effect between the frequency of equipment and structure. The seismic capacity of equipment by the Zion method can be different from the real seismic capacity of equipment because the inelastic structure response factor has nothing to do with the ductility of structure. Therefore the median and COV for FRSR should be defined considering the ductility of structure and the frequency of equipment for more exactly evaluating the seismic capacity of equipment.

  19. The relationship between shock response spectrum and fast Fourier transform

    International Nuclear Information System (INIS)

    Zola, Maurizio

    2001-01-01

    In this paper the basic relationship between response spectrum and fast Fourier transform is laid down. Since a long time the response spectrum has been used by structural engineers in the seismic domain and nowadays it is going to be used to define transient motions. This way to define the excitation is more general and more real than the use of classical shape pulses for the reproduction of real environment. Nevertheless the response spectrum of a real excitation represents a loss of some information with respect to the Fourier transform. A useful discussion could arise from these observations. Appendix A gives the relationship between the mathematic Fourier transform and the digital Fourier transform given by computers, while Appendix B gives some examples of response spectra and Fourier transforms of simple functions. (author)

  20. Power/response spectrum transformations in equipment qualification

    International Nuclear Information System (INIS)

    Unruh, J.F.; Kana, D.D.

    1985-01-01

    Since its introduction a few years ago the use of the power/response spectrum transformation has gained considerable interest and acceptance, and a number of new applications of the transformation have been developed in the equipment qualification area. A brief review of the power/response spectrum transformation is given with a discussion of the input/output relationships for linear systems required for elevated power spectrum generation. Frequency content of earthquakelike signals is discussed with emphasis on the resolution given by the PSD. The problem of excessive ZPA due to inconsistent spectra enveloping and mechanical nonlinearities is also discussed. The PSD/RS transformation is applied to the problems of combining various dynamic load events, developing bounding spectra, and developing damping consistent test spectra. Development of elevated component spectra corrected for base overtest and generation from in-situ measurements is reviewed

  1. Speed testing of Sliding spectrum analysis

    International Nuclear Information System (INIS)

    Frenski, Emil; Manolev, Dimitar

    2013-01-01

    The standard method for spectrum analysis in DSP is the Discrete Fourier transform (DFT), typically implemented using a Fast Fourier transform (FFT) algorithm. The reconstruction of the time-domain signal is then performed by the IFFT (Inverse Fast Fourier transform) algorithm. The FFT calculates the spectral components in a window, on a block-by-block basis. If that window is move by one sample, it is obvious that most of the information will remain the same. This article shows how to measure execution time of scripts realizing SDFT algorithm written for MatLab

  2. A time-domain method to generate artificial time history from a given reference response spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Gang Sik [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of); Song, Oh Seop [Dept. of Mechanical Engineering, Chungnam National University, Daejeon (Korea, Republic of)

    2016-06-15

    Seismic qualification by test is widely used as a way to show the integrity and functionality of equipment that is related to the overall safety of nuclear power plants. Another means of seismic qualification is by direct integration analysis. Both approaches require a series of time histories as an input. However, in most cases, the possibility of using real earthquake data is limited. Thus, artificial time histories are widely used instead. In many cases, however, response spectra are given. Thus, most of the artificial time histories are generated from the given response spectra. Obtaining the response spectrum from a given time history is straightforward. However, the procedure for generating artificial time histories from a given response spectrum is difficult and complex to understand. Thus, this paper presents a simple time-domain method for generating a time history from a given response spectrum; the method was shown to satisfy conditions derived from nuclear regulatory guidance.

  3. A time-domain method to generate artificial time history from a given reference response spectrum

    International Nuclear Information System (INIS)

    Shin, Gang Sik; Song, Oh Seop

    2016-01-01

    Seismic qualification by test is widely used as a way to show the integrity and functionality of equipment that is related to the overall safety of nuclear power plants. Another means of seismic qualification is by direct integration analysis. Both approaches require a series of time histories as an input. However, in most cases, the possibility of using real earthquake data is limited. Thus, artificial time histories are widely used instead. In many cases, however, response spectra are given. Thus, most of the artificial time histories are generated from the given response spectra. Obtaining the response spectrum from a given time history is straightforward. However, the procedure for generating artificial time histories from a given response spectrum is difficult and complex to understand. Thus, this paper presents a simple time-domain method for generating a time history from a given response spectrum; the method was shown to satisfy conditions derived from nuclear regulatory guidance

  4. Modification of evaluation response spectrum by ductility of equipment anchorage

    International Nuclear Information System (INIS)

    Choi, I. G.; Jun, Y. S.; Su, J. M.

    2003-01-01

    The failure mode of welded anchorage is assumed as brittle in the seismic capacity evaluation of nuclear power plant equipments. But the welded anchorage has some ductile capacity. This limited displacement capacity can cause the reduction of the effective frequency of high frequency equipments and the increase of the inelastic energy absorption capacity due to the nonlinear behavior. In this study, the uniform hazard spectrum for Korean nuclear power plant site was modified using the response spectrum reduction factor developed by EPRI. The spectral acceleration for various damping ratio was determined by the theoretical method based on the random vibration theory. In conclusion, the high frequency components of evaluation response spectra were greatly reduced due to the consideration of welded anchorage ductility. This reduced response spectra can be used for the development of in-structure response spectra used in the seismic capacity evaluation of high frequency equipments

  5. Seismic response of structures by the response spectrum method

    International Nuclear Information System (INIS)

    Hadjian, A.H.

    1981-01-01

    The problems of the acceleration profile at the lower elevations of cantilever structures and the response of relatively rigid structures are explored. It is shown that the use of the conventional methods for the above problems provide very approximate results. An alternate combination of the modal responses is proposed that not only resolves the above problems but also provides better estimates of response for the complete range of structure frequencies. The procedure treats the relative and rigid body responses separately and then appropriately combines the two results. For the rigid range of frequencies (fundamental frequencies greater than about 2 Hz), the proposed procedure does not encounter any numerical difficulties because of the additive nature of the component responses; however, the application of the proposed procedure for very flexible structures causes accuracy problems since the rigid body effects tend to be subtractive from the flexural response of about equal magnitude. For this latter class of problems, the conventional approach of modal combination provides adequate results and avoids the above mentioned numerical difficulties. (orig.)

  6. Aquaporin-4 serostatus does not predict response to immunotherapy in neuromyelitis optica spectrum disorders.

    Science.gov (United States)

    Mealy, Maureen A; Kim, Su-Hyun; Schmidt, Felix; López, Reydmar; Jimenez Arango, Jorge A; Paul, Friedemann; Wingerchuk, Dean M; Greenberg, Benjamin M; Kim, Ho Jin; Levy, Michael

    2017-08-01

    Debate exists about whether neuromyelitis optica spectrum disorder seronegative disease represents the same immune-mediated attack on astrocytic aquaporin-4 as in seropositive disease. We investigated whether response to common treatments for neuromyelitis optica spectrum disorder differed by serostatus, as assessed by change in annualized relapse rate. We performed a multicenter retrospective analysis of 245 patients with neuromyelitis optica spectrum disorder who were treated with either rituximab or mycophenolate mofetil as their first-line immunosuppressive treatment for disease prevention. Patients were followed for a minimum of 6 months following treatment initiation. In those started on rituximab, the pre-treatment annualized relapse rates for seropositive and seronegative patients were 1.81 and 1.93, respectively. On-treatment annualized relapse rates significantly declined to 0.32 (seropositive; p optica spectrum disorder patients, treatment was effective regardless of serostatus. This suggests that treatment should not differ when considering these treatments.

  7. TVWS devices spectrum mask test and analysis

    CSIR Research Space (South Africa)

    Lamola, MM

    2016-09-01

    Full Text Available Dynamic Spectrum Access (DSA) plays a vital role in opportunistic access to spectrum. A key component of DSA is preventing interference to the incumbent (primary) user from the secondary user. We present the results of an experiment to analyze...

  8. Calculation of fluid (steam) hammer loading to piping systems by the response spectrum method

    International Nuclear Information System (INIS)

    Krause, G.; Schrader, W.; Leimbach, K.R.

    1983-01-01

    Today computations of fluid and steam hammer loading to piping systems are usually performed as a time-history analysis in which the transient pressure forces act as external excitations. For practical purposes it is desirable to be able to treat fluid hammer loading using the response spectrum method similarily as loads from external events. Two advantages arise from the use of spectra in the analysis of piping systems subjected to dynamic force excitations. Firstly, the response spectrum method is much less sensitive to model idealization than the time-history method. Secondly, computational efforts are reduced. In this paper the algorithm for the treatment of force excitations through the modal response spectrum method is briefly presented. The effect of the residuum accounting for higher modes which are not part of the modal decomposition is considered. In particular various methods of superposition of the responses of the dynamic forces and of the modes are investigated. Results and comparisons are presented of several response spectrum analyses and time-history analyses. (orig.)

  9. Pivotal response treatment for autism spectrum disorder: current perspectives

    Directory of Open Access Journals (Sweden)

    Lei J

    2017-06-01

    Full Text Available Jiedi Lei, Pamela Ventola Yale Child Study Center, Yale University School of Medicine, New Haven, CT, USA Abstract: Pivotal response treatment (PRT is an evidence-based behavioral intervention based on applied behavior analysis principles aimed to improve social communication skills in individuals with autism spectrum disorder (ASD. PRT adopts a more naturalistic approach and focuses on using a number of strategies to help increase children’s motivation during intervention. Since its conceptualization, PRT has received much empirical support for eliciting therapeutic gains in greater use of functional social communication skills in individuals with ASD. Building upon the empirical evidence supporting PRT, recent advancements have increasingly turned to using interdisciplinary research integrating neuroimaging techniques and behavioral measures to help identify objective biomarkers of treatment, which have two primary purposes. First, neuroimaging results can help characterize how PRT may elicit change, and facilitate partitioning of the heterogeneous profiles of neural mechanisms underlying similar profile of behavioral changes observed over PRT. Second, neuroimaging provides an objective means to both map and track how biomarkers may serve as reliable and sensitive predictors of responder profiles to PRT, assisting clinicians to identify who will most likely benefit from PRT. Together, a better understanding of both mechanisms of change and predictors of responder profile will help PRT to serve as a more precise and targeted intervention for individuals with ASD, thus moving towards the goal of precision medicine and improving quality of care. This review focuses on the recent emerging neuroimaging evidences supporting PRT, offering current perspectives on the importance of interdisciplinary research to help clinicians better understand how PRT works and predict who will respond to PRT. Keywords: PRT, ASD, biomarkers, neuroimaging

  10. Seismic analysis of a NPP reactor building using spectrum-compatible power spectral density functions

    International Nuclear Information System (INIS)

    Venancio Filho, F.; DeCarvalho Santos, S.H.; Joia, L.A.

    1987-01-01

    A numerical methodology to obtain Power Spectral Density Functions (PSDF) of ground accelerations, compatible with a given design response spectrum is presented. The PSDF's are derived from the statistical analysis of the amplitudes of the frequency components in a set of artificially generated time-histories matching the given spectrum. A so obtained PSDF is then used in the stochastic analysis of a NPP Reactor Building. The main results of this analysis are compared with the ones obtained by deterministic methods

  11. Seismic analysis of a NPP reactor building using spectrum-compatible power spectral density functions

    International Nuclear Information System (INIS)

    Venancio Filho, F.; Joia, L.A.

    1987-01-01

    A numerical methodology to obtain Power Spectral Density Functions (PSDF) of ground accelerations, compatible with a given design response spectrum is presented. The PSDF's are derived from the statistical analysis of the amplitudes of the frequency components in a set of artificially generated time-histories matching the given spectrum. A so obtained PSDF is then used in the stochastic analysis of a reactor building. The main results of this analysis are compared with the ones obtained by deterministic methods. (orig./HP)

  12. Power spectrum analysis for defect screening in integrated circuit devices

    Science.gov (United States)

    Tangyunyong, Paiboon; Cole Jr., Edward I.; Stein, David J.

    2011-12-01

    A device sample is screened for defects using its power spectrum in response to a dynamic stimulus. The device sample receives a time-varying electrical signal. The power spectrum of the device sample is measured at one of the pins of the device sample. A defect in the device sample can be identified based on results of comparing the power spectrum with one or more power spectra of the device that have a known defect status.

  13. Analytical procedure in aseismic design of eccentric structure using response spectrum

    International Nuclear Information System (INIS)

    Takemori, T.; Kuwabara, Y.; Suwabe, A.; Mitsunobu, S.

    1977-01-01

    In this paper, the response are evaluated by the following two methods by the use of the typical torsional analytical models in which masses, rigidities, eccentricities between the centers thereof and several actual earthquake waves are taken as the parameters: (1) the root mean square of responses by using the response spectra derived from the earthquake waves, (2) the time history analysis by using the earthquake wave. The earthquake waves used are chosen to present the different frequency content and magnitude of the response spectra. The typical results derived from the study are as follows: (a) the response accelerations of mass center in the input earthquake direction by the (1) method coincide comparatively well with those by the (2) method, (b) the response accelerations perpendicular to the input earthquake direction by (1) method are 2 to 3 times as much as those by the (2) method, (c) the amplification of the response accelerations at arbitrary points distributed on the spread mass to those of center of the lumped mass by the (1) method are remarkably large compared with those by the (2) method in both directions respectively. These problems on the response spectrum analysis for the above-mentioned eccentric structure are discussed, and an improved analytical method applying the amplification coefficients of responses derived from this parametric time history analysis is proposed to the actual seismic design by the using of the given design ground response spectrum with root mean square technique

  14. Decision Analysis of Dynamic Spectrum Access Rules

    Energy Technology Data Exchange (ETDEWEB)

    Juan D. Deaton; Luiz A. DaSilva; Christian Wernz

    2011-12-01

    A current trend in spectrum regulation is to incorporate spectrum sharing through the design of spectrum access rules that support Dynamic Spectrum Access (DSA). This paper develops a decision-theoretic framework for regulators to assess the impacts of different decision rules on both primary and secondary operators. We analyze access rules based on sensing and exclusion areas, which in practice can be enforced through geolocation databases. Our results show that receiver-only sensing provides insufficient protection for primary and co-existing secondary users and overall low social welfare. On the other hand, using sensing information between the transmitter and receiver of a communication link, provides dramatic increases in system performance. The performance of using these link end points is relatively close to that of using many cooperative sensing nodes associated to the same access point and large link exclusion areas. These results are useful to regulators and network developers in understanding in developing rules for future DSA regulation.

  15. Natural gamma ray spectrum analysis technique

    International Nuclear Information System (INIS)

    Chevalier, P.; Seeman, B.

    1976-01-01

    In accordance with an illustrative embodiment of the present invention, a method and apparatus is disclosed for determining the presence of a selected number of naturally radioactive materials in an earth formation from the spectrum of natural gamma radiation emitted by the materials in the formation by deriving representations of portions of the detected gamma radiation spectrum and combining the representations to determine therefrom the presence of the selected materials

  16. Spectrum

    DEFF Research Database (Denmark)

    Høgfeldt Hansen, Leif

    2016-01-01

    The publication functions as a proces description of the development and construction of an urban furniture SPECTRUM in the city of Gwangju, Republic of Korea. It is used as the cataloque for the exhibition of Spectrum.......The publication functions as a proces description of the development and construction of an urban furniture SPECTRUM in the city of Gwangju, Republic of Korea. It is used as the cataloque for the exhibition of Spectrum....

  17. A Response to Papatola and Lustig's Paper on Navigating a Managed Care Peer Review: Guidance for Clinicians Using Applied Behavior Analysis in the Treatment of Children on the Autism Spectrum.

    Science.gov (United States)

    Kornack, Julie; Herscovitch, Brandon; Williams, Ashley L

    2017-12-01

    In their 2016 article, "Navigating a Managed Care Peer Review: Guidance for Clinicians Using Applied Behavior Analysis [ABA] in the Treatment of Children on the Autism Spectrum," Papatola and Lustig provide an overview of the managed care process, discuss the medical necessity of ABA, and offer guidance to clinicians on how to navigate the managed care peer review process. Given that the authors are employed by a large international health insurance carrier and conduct peer reviews on behalf of that organization, this response seeks to provide guidance from both the clinical and public policy perspectives that reflect best practices in the field of autism treatment. This response is not written with the intention of providing or replacing legal advice; rather, this paper offers health care providers of ABA an essential understanding of some of the laws that govern and support their efforts to secure medically necessary treatment and the mechanisms in place with which to challenge decisions by managed care organizations, health plans, and health insurance issuers that may be contrary to best practices. Finally, suggestions are offered on how to navigate a peer review to ensure optimal outcomes and, when necessary, to lay the groundwork to overturn a funding source decision that does not reflect best practices or the standard of care in ABA-based autism treatment.

  18. Uncertainty analysis of dosimetry spectrum unfolding

    International Nuclear Information System (INIS)

    Perey, F.G.

    1977-01-01

    The propagation of uncertainties in the input data is analyzed for the usual dosimetry unfolding solution. A new formulation of the dosimetry unfolding problem is proposed in which the most likely value of the spectrum is obtained. The relationship of this solution to the usual one is discussed

  19. Gamma-ray pulse height spectrum analysis on systems with multiple Ge detectors using spectrum summing

    Energy Technology Data Exchange (ETDEWEB)

    Killian, E.W. [Idaho National Engineering Lab., Idaho Falls, ID (United States)

    1997-11-01

    A technique has been developed at the Idaho National Engineering Laboratory to sum high resolution gamma-ray pulse spectra from systems with multiple Ge detectors. Lockheed Martin Idaho Technologies Company operates a multi-detector spectrometer configuration at the Stored Waste Examination Pilot Plant facility which is used to characterize the radionuclide contents in waste drums destined for shipment to Waste Isolation Pilot Plant. This summing technique was developed to increase the sensitivity of the system, reduce the count times required to properly quantify the radio-nuclides and provide a more consistent methodology for combining data collected from multiple detectors. In spectrometer systems with multiple detectors looking at non homogeneous waste forms it is often difficult to combine individual spectrum analysis results from each detector to obtain a meaningful result for the total waste container. This is particularly true when the counting statistics in each individual spectrum are poor. The spectrum summing technique adds the spectra collected by each detector into a single spectrum which has better counting statistics than each individual spectrum. A normal spectral analysis program can then be used to analyze the sum spectrum to obtain radio-nuclide values which have smaller errors and do not have to be further manipulated to obtain results for the total waste container. 2 refs., 2 figs.

  20. Affective neural response to restricted interests in autism spectrum disorders.

    Science.gov (United States)

    Cascio, Carissa J; Foss-Feig, Jennifer H; Heacock, Jessica; Schauder, Kimberly B; Loring, Whitney A; Rogers, Baxter P; Pryweller, Jennifer R; Newsom, Cassandra R; Cockhren, Jurnell; Cao, Aize; Bolton, Scott

    2014-01-01

    Restricted interests are a class of repetitive behavior in autism spectrum disorders (ASD) whose intensity and narrow focus often contribute to significant interference with daily functioning. While numerous neuroimaging studies have investigated executive circuits as putative neural substrates of repetitive behavior, recent work implicates affective neural circuits in restricted interests. We sought to explore the role of affective neural circuits and determine how restricted interests are distinguished from hobbies or interests in typical development. We compared a group of children with ASD to a typically developing (TD) group of children with strong interests or hobbies, employing parent report, an operant behavioral task, and functional imaging with personalized stimuli based on individual interests. While performance on the operant task was similar between the two groups, parent report of intensity and interference of interests was significantly higher in the ASD group. Both the ASD and TD groups showed increased BOLD response in widespread affective neural regions to the pictures of their own interest. When viewing pictures of other children's interests, the TD group showed a similar pattern, whereas BOLD response in the ASD group was much more limited. Increased BOLD response in the insula and anterior cingulate cortex distinguished the ASD from the TD group, and parent report of the intensity and interference with daily life of the child's restricted interest predicted insula response. While affective neural network response and operant behavior are comparable in typical and restricted interests, the narrowness of focus that clinically distinguishes restricted interests in ASD is reflected in more interference in daily life and aberrantly enhanced insula and anterior cingulate response to individuals' own interests in the ASD group. These results further support the involvement of affective neural networks in repetitive behaviors in ASD. © 2013 The

  1. Altered responses to social chemosignals in autism spectrum disorder.

    Science.gov (United States)

    Endevelt-Shapira, Yaara; Perl, Ofer; Ravia, Aharon; Amir, Daniel; Eisen, Ami; Bezalel, Vered; Rozenkrantz, Liron; Mishor, Eva; Pinchover, Liron; Soroka, Timna; Honigstein, Danielle; Sobel, Noam

    2018-01-01

    Autism spectrum disorder (ASD) is characterized by impaired social communication, often attributed to misreading of emotional cues. Why individuals with ASD misread emotions remains unclear. Given that terrestrial mammals rely on their sense of smell to read conspecific emotions, we hypothesized that misreading of emotional cues in ASD partially reflects altered social chemosignaling. We found no difference between typically developed (TD) and cognitively able adults with ASD at explicit detection and perception of social chemosignals. Nevertheless, TD and ASD participants dissociated in their responses to subliminal presentation of these same compounds: the undetected 'smell of fear' (skydiver sweat) increased physiological arousal and reduced explicit and implicit measures of trust in TD but acted opposite in ASD participants. Moreover, two different undetected synthetic putative social chemosignals increased or decreased arousal in TD but acted opposite in ASD participants. These results implicate social chemosignaling as a sensory substrate of social impairment in ASD.

  2. CAX a software for automated spectrum analysis

    International Nuclear Information System (INIS)

    Zahn, Guilherme S.; Genezini, Frederico A.

    2017-01-01

    In this work, the scripting capabilities of Genie-2000 were used to develop a software that automatically analyses all spectrum files in either Ortec's CHN or Canberra's MCA or CNF formats in a folder, generating two output files: a print-ready text le (.DAT) and a Comma-Separated Values (.CSV) le which can be easily imported in any major spreadsheet software. This software, named CAX ('Convert and Analyse for eXcel'), uses Genie-2000's functions to import spectrum files into Genie's native CNF format and analyze the converted spectra. The software can also, if requested, import energy and FWHM calibrations from a stored calibrated spectrum. The print-ready output le (.DAT) is generated by Genie-2000 using a customized script, and the CSV le is generated by a custom-built DAT2CSV software which generates a CSV le that complies to the Brazilian standards, with commas as a decimal indicator and semicolons as eld separators. This software is already used in the daily routines in IPEN's Neutron Activation Laboratory, greatly reducing the time required for sample analyses, as well as reducing the possibility of transcription errors. (author)

  3. CAX a software for automated spectrum analysis

    Energy Technology Data Exchange (ETDEWEB)

    Zahn, Guilherme S.; Genezini, Frederico A., E-mail: gzahn@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (CRPq/IPEN/CNEN-SP), Sao Paulo, SP (Brazil). Centro do Reator de Pesquisas

    2017-11-01

    In this work, the scripting capabilities of Genie-2000 were used to develop a software that automatically analyses all spectrum files in either Ortec's CHN or Canberra's MCA or CNF formats in a folder, generating two output files: a print-ready text le (.DAT) and a Comma-Separated Values (.CSV) le which can be easily imported in any major spreadsheet software. This software, named CAX ('Convert and Analyse for eXcel'), uses Genie-2000's functions to import spectrum files into Genie's native CNF format and analyze the converted spectra. The software can also, if requested, import energy and FWHM calibrations from a stored calibrated spectrum. The print-ready output le (.DAT) is generated by Genie-2000 using a customized script, and the CSV le is generated by a custom-built DAT2CSV software which generates a CSV le that complies to the Brazilian standards, with commas as a decimal indicator and semicolons as eld separators. This software is already used in the daily routines in IPEN's Neutron Activation Laboratory, greatly reducing the time required for sample analyses, as well as reducing the possibility of transcription errors. (author)

  4. CISAPS: Complex Informational Spectrum for the Analysis of Protein Sequences

    Directory of Open Access Journals (Sweden)

    Charalambos Chrysostomou

    2015-01-01

    Full Text Available Complex informational spectrum analysis for protein sequences (CISAPS and its web-based server are developed and presented. As recent studies show, only the use of the absolute spectrum in the analysis of protein sequences using the informational spectrum analysis is proven to be insufficient. Therefore, CISAPS is developed to consider and provide results in three forms including absolute, real, and imaginary spectrum. Biologically related features to the analysis of influenza A subtypes as presented as a case study in this study can also appear individually either in the real or imaginary spectrum. As the results presented, protein classes can present similarities or differences according to the features extracted from CISAPS web server. These associations are probable to be related with the protein feature that the specific amino acid index represents. In addition, various technical issues such as zero-padding and windowing that may affect the analysis are also addressed. CISAPS uses an expanded list of 611 unique amino acid indices where each one represents a different property to perform the analysis. This web-based server enables researchers with little knowledge of signal processing methods to apply and include complex informational spectrum analysis to their work.

  5. Frequency spectrum analysis of finger photoplethysmographic waveform variability during haemodialysis.

    Science.gov (United States)

    Javed, Faizan; Middleton, Paul M; Malouf, Philip; Chan, Gregory S H; Savkin, Andrey V; Lovell, Nigel H; Steel, Elizabeth; Mackie, James

    2010-09-01

    This study investigates the peripheral circulatory and autonomic response to volume withdrawal in haemodialysis based on spectral analysis of photoplethysmographic waveform variability (PPGV). Frequency spectrum analysis was performed on the baseline and pulse amplitude variabilities of the finger infrared photoplethysmographic (PPG) waveform and on heart rate variability extracted from the ECG signal collected from 18 kidney failure patients undergoing haemodialysis. Spectral powers were calculated from the low frequency (LF, 0.04-0.145 Hz) and high frequency (HF, 0.145-0.45 Hz) bands. In eight stable fluid overloaded patients (fluid removal of >2 L) not on alpha blockers, progressive reduction in relative blood volume during haemodialysis resulted in significant increase in LF and HF powers of PPG baseline and amplitude variability (P analysis of finger PPGV may provide valuable information on the autonomic vascular response to blood volume reduction in haemodialysis, and can be potentially utilized as a non-invasive tool for assessing peripheral circulatory control during routine dialysis procedure.

  6. Response to unfairness across the suicide risk spectrum.

    Science.gov (United States)

    Carbajal, Jessica M; Gamboa, Jorge L; Moore, Jordan; Smith, Favrin; Ann Eads, Lou; Clothier, Jeffrey L; Cáceda, Ricardo

    2017-12-01

    Suicidal behavior is frequently triggered by social crises, such as familial, romantic, social or work-related conflict. A variety of cognitive and social functioning impairments has been associated with suicidal thoughts and acts. One of the precipitating and perpetuating factors of social conflict is the desire for retribution after a perceived offense, even at one's own detriment. We utilized the Ultimatum Game-a behavioral economic task which examines the behavioral response to perceived unfairness-in order to characterize the response to unfairness across the acute suicide risk spectrum. We examined five groups of adult individuals of both genders (n = 204): High- and Low-Lethality recent Suicide Attempters, Suicidal Ideators, Non-Suicidal Depressed Patients; and Healthy Controls. We also measured demographic and clinical variables. Even though all depressed groups showed similar rejection rates in the Ultimatum Game, there was a higher likelihood of rejecting offers in the low stakes condition in all acutely suicidal groups compared with healthy controls. Stake size, offer, education, and gender of the proposer were significantly associated with rejection rates. Acutely suicidal patients may be more vulnerable to adverse interpersonal interactions. Further characterization of social behavior may provide targets for secondary and tertiary prevention for high-risk individuals. Published by Elsevier B.V.

  7. Performing dynamic time history analyses by extension of the response spectrum method

    International Nuclear Information System (INIS)

    Hulbert, G.M.

    1983-01-01

    A method is presented to calculate the dynamic time history response of finite-element models using results from response spectrum analyses. The proposed modified time history method does not represent a new mathamatical approach to dynamic analysis but suggests a more efficient ordering of the analytical equations and procedures. The modified time history method is considerably faster and less expensive to use than normal time hisory methods. This paper presents the theory and implementation of the modified time history approach along with comparisons of the modified and normal time history methods for a prototypic seismic piping design problem

  8. SINGULAR SPECTRUM ANALYSIS: METHODOLOGY AND APPLICATION TO ECONOMICS DATA

    Institute of Scientific and Technical Information of China (English)

    Hossein HASSANI; Anatoly ZHIGLJAVSKY

    2009-01-01

    This paper describes the methodology of singular spectrum analysis (SSA) and demonstrate that it is a powerful method of time series analysis and forecasting, particulary for economic time series. The authors consider the application of SSA to the analysis and forecasting of the Iranian national accounts data as provided by the Central Bank of the Islamic Republic of lran.

  9. Heart Sound Biometric System Based on Marginal Spectrum Analysis

    Science.gov (United States)

    Zhao, Zhidong; Shen, Qinqin; Ren, Fangqin

    2013-01-01

    This work presents a heart sound biometric system based on marginal spectrum analysis, which is a new feature extraction technique for identification purposes. This heart sound identification system is comprised of signal acquisition, pre-processing, feature extraction, training, and identification. Experiments on the selection of the optimal values for the system parameters are conducted. The results indicate that the new spectrum coefficients result in a significant increase in the recognition rate of 94.40% compared with that of the traditional Fourier spectrum (84.32%) based on a database of 280 heart sounds from 40 participants. PMID:23429515

  10. The Analysis of the Disease Spectrum in China

    Directory of Open Access Journals (Sweden)

    Xin Zhang

    2014-01-01

    Full Text Available Analysis of the related risks of disease provides a scientific basis for disease prevention and treatment, hospital management, and policy formulation by the changes in disease spectrum of patients in hospital. Retrospective analysis was made to the first diagnosis, age, gender, daily average cost of hospitalized patients, and other factors in the First Affiliated Hospital of Nanjing Medical University during 2006–2013. The top 4 cases were as follows: cardiovascular disease, malignant tumors, lung infections, and noninsulin dependent diabetes mellitus. By the age of disease analysis, we found a younger age trend of cardiovascular disease, and the age of onset of cancer or diabetes was somewhat postponed. The average daily cost of hospitalization and the average daily cost of the main noncommunicable diseases were both on the rise. Noncommunicable diseases occupy an increasingly important position in the constitution of the disease, and they caused an increasing medical burden. People should pay attention to health from the aspects of lifestyle changing. Hospitals should focus on building the appropriate discipline. On the other hand, an integrated government response is required to tackle key risks. Multiple interventions are needed to lower the burden of these diseases and to improve national health.

  11. THE MURCHISON WIDEFIELD ARRAY 21 cm POWER SPECTRUM ANALYSIS METHODOLOGY

    Energy Technology Data Exchange (ETDEWEB)

    Jacobs, Daniel C.; Beardsley, A. P.; Bowman, Judd D. [Arizona State University, School of Earth and Space Exploration, Tempe, AZ 85287 (United States); Hazelton, B. J.; Sullivan, I. S.; Barry, N.; Carroll, P. [University of Washington, Department of Physics, Seattle, WA 98195 (United States); Trott, C. M.; Pindor, B.; Briggs, F.; Gaensler, B. M. [ARC Centre of Excellence for All-sky Astrophysics (CAASTRO) (Australia); Dillon, Joshua S.; Oliveira-Costa, A. de; Ewall-Wice, A.; Feng, L. [MIT Kavli Institute for Astrophysics and Space Research, Cambridge, MA 02139 (United States); Pober, J. C. [Brown University, Department of Physics, Providence, RI 02912 (United States); Bernardi, G. [Department of Physics and Electronics, Rhodes University, Grahamstown 6140 (South Africa); Cappallo, R. J.; Corey, B. E. [MIT Haystack Observatory, Westford, MA 01886 (United States); Emrich, D., E-mail: daniel.c.jacobs@asu.edu [International Centre for Radio Astronomy Research, Curtin University, Perth, WA 6845 (Australia); and others

    2016-07-10

    We present the 21 cm power spectrum analysis approach of the Murchison Widefield Array Epoch of Reionization project. In this paper, we compare the outputs of multiple pipelines for the purpose of validating statistical limits cosmological hydrogen at redshifts between 6 and 12. Multiple independent data calibration and reduction pipelines are used to make power spectrum limits on a fiducial night of data. Comparing the outputs of imaging and power spectrum stages highlights differences in calibration, foreground subtraction, and power spectrum calculation. The power spectra found using these different methods span a space defined by the various tradeoffs between speed, accuracy, and systematic control. Lessons learned from comparing the pipelines range from the algorithmic to the prosaically mundane; all demonstrate the many pitfalls of neglecting reproducibility. We briefly discuss the way these different methods attempt to handle the question of evaluating a significant detection in the presence of foregrounds.

  12. A note on probabilistic computation of earthquake response spectrum amplitudes

    International Nuclear Information System (INIS)

    Anderson, J.G.; Trifunac, M.D.

    1979-01-01

    This paper analyzes a method for computation of Pseudo Relative Velocity (PSV) spectrum and Absolute Acceleration (SA) spectrum so that the amplitudes and the shapes of these spectra reflect the geometrical characteristics of the seismic environment of the site. The estimated spectra also incorporate the geologic characteristics at the site, direction of ground motion and the probability of exceeding these motions. An example of applying this method in a realistic setting is presented and the uncertainties of the results are discussed. (Auth.)

  13. Performance analysis of distributed beamforming in a spectrum sharing system

    KAUST Repository

    Yang, Liang; Alouini, Mohamed-Slim; Qaraqe, Khalid A.

    2012-01-01

    In this paper, we consider a distributed beamforming scheme (DBF) in a spectrum sharing system where multiple secondary users share the spectrum with the licensed primary users under an interference temperature constraint. We assume that DBF is applied at the secondary users. We first consider optimal beamforming and compare it with the user selection scheme in terms of the outage probability and bit-error rate performance. Since perfect feedback is difficult to obtain, we then investigate a limited feedback DBF scheme and develop an outage probability analysis for a random vector quantization (RVQ) design algorithm. Numerical results are provided to illustrate our mathematical formalism and verify our analysis. © 2012 IEEE.

  14. Performance analysis of distributed beamforming in a spectrum sharing system

    KAUST Repository

    Yang, Liang

    2012-09-01

    In this paper, we consider a distributed beamforming scheme (DBF) in a spectrum sharing system where multiple secondary users share the spectrum with the licensed primary users under an interference temperature constraint. We assume that DBF is applied at the secondary users. We first consider optimal beamforming and compare it with the user selection scheme in terms of the outage probability and bit-error rate performance. Since perfect feedback is difficult to obtain, we then investigate a limited feedback DBF scheme and develop an outage probability analysis for a random vector quantization (RVQ) design algorithm. Numerical results are provided to illustrate our mathematical formalism and verify our analysis. © 2012 IEEE.

  15. Analysis of the biological spectrum of vascular flora of Ravni Srem flood forests

    Directory of Open Access Journals (Sweden)

    Jurišić Branislav

    2011-01-01

    Full Text Available One of the essential analyses performed during the floristic study of a region is the analysis of the biological spectrum. The analysis of the biological spectrum of the flora includes the determination of the type of life form for each taxon described in the flora of the study region. If it is considered that life form is a specific structural-functional response to the environmental effects and the result of the adaptation during the species evolution, it is clear that the basic characteristics of the site are more or less reflected in any life form. This fact is confirmed by the analysis of the biological spectrum of the flora of Ravni Srem. The analysis of the Ravni Srem flora shows the domination of the hemicryptophytes and the subdomination of the phanerophytes with a considerable participation of the therophytes.

  16. Spectrum analysis on quality requirements consideration in software design documents.

    Science.gov (United States)

    Kaiya, Haruhiko; Umemura, Masahiro; Ogata, Shinpei; Kaijiri, Kenji

    2013-12-01

    Software quality requirements defined in the requirements analysis stage should be implemented in the final products, such as source codes and system deployment. To guarantee this meta-requirement, quality requirements should be considered in the intermediate stages, such as the design stage or the architectural definition stage. We propose a novel method for checking whether quality requirements are considered in the design stage. In this method, a technique called "spectrum analysis for quality requirements" is applied not only to requirements specifications but also to design documents. The technique enables us to derive the spectrum of a document, and quality requirements considerations in the document are numerically represented in the spectrum. We can thus objectively identify whether the considerations of quality requirements in a requirements document are adapted to its design document. To validate the method, we applied it to commercial software systems with the help of a supporting tool, and we confirmed that the method worked well.

  17. 2009 Autism Spectrum Disorder Research: Portfolio Analysis Report

    Science.gov (United States)

    Interagency Autism Coordinating Committee, 2011

    2011-01-01

    In 2010, the Office of Autism Research Coordination (OARC) and Acclaro Research Solutions, Inc., on behalf of the Interagency Autism Coordinating Committee (IACC), conducted a comprehensive analysis of the 2009 autism spectrum disorder (ASD) research portfolio of major Federal agencies and private organizations. This is the second annual analysis…

  18. Application of frequency spectrum analysis in the rotator moving equilibrium

    International Nuclear Information System (INIS)

    Liu Ruilan; Su Guanghui; Shang Zhi; Jia Dounan

    2001-01-01

    The experimental equipment is developed to simulate the rotator vibration. The running state of machine is simulated by using different running conditions. The vibration caused by non-equilibrium mass is analyzed and discussed for first order with focus load. The effective method is found out by using frequency spectrum analysis

  19. Singular spectrum analysis, Harmonic regression and El-Nino effect ...

    Indian Academy of Sciences (India)

    42

    Keywords: Total ozone; Singular Spectrum Analysis; Spatial interpolation; Multivariate ENSO .... needed for a whole gamut of activities that contribute to the ultimate synthesis ..... −0.0009 3 + 0.0581 2 − 1.0123 + 7.3246, 2 = 0.53…

  20. Frequency Response Analysis Tool

    Energy Technology Data Exchange (ETDEWEB)

    Etingov, Pavel V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kosterev, Dmitry [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Dai, T. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-12-01

    Frequency response has received a lot of attention in recent years at the national level, which culminated in the development and approval of North American Electricity Reliability Corporation (NERC) BAL-003-1 Frequency Response and Frequency Bias Setting Reliability Standard. This report is prepared to describe the details of the work conducted by Pacific Northwest National Laboratory (PNNL) in collaboration with the Bonneville Power Administration and Western Electricity Coordinating Council (WECC) Joint Synchronized Information Subcommittee (JSIS) to develop a frequency response analysis tool (FRAT). The document provides the details on the methodology and main features of the FRAT. The tool manages the database of under-frequency events and calculates the frequency response baseline. Frequency response calculations are consistent with frequency response measure (FRM) in NERC BAL-003-1 for an interconnection and balancing authority. The FRAT can use both phasor measurement unit (PMU) data, where available, and supervisory control and data acquisition (SCADA) data. The tool is also capable of automatically generating NERC Frequency Response Survey (FRS) forms required by BAL-003-1 Standard.

  1. Pushover, Response Spectrum and Time History Analyses of Safe Rooms in a Poor Performance Masonry Building

    International Nuclear Information System (INIS)

    Mazloom, M.

    2008-01-01

    The idea of safe room has been developed for decreasing the earthquake casualties in masonry buildings. The information obtained from the previous ground motions occurring in seismic zones expresses the lack of enough safety of these buildings against earthquakes. For this reason, an attempt has been made to create some safe areas inside the existing masonry buildings, which are called safe rooms. The practical method for making these safe areas is to install some prefabricated steel frames in some parts of the existing structure. These frames do not carry any service loads before an earthquake. However, if a devastating earthquake happens and the load bearing walls of the building are destroyed, some parts of the floors, which are in the safe areas, will fall on the roof of the installed frames and the occupants who have sheltered there will survive. This paper presents the performance of these frames located in a destroying three storey masonry building with favorable conclusions. In fact, the experimental pushover diagram of the safe room located at the ground-floor level of this building is compared with the analytical results and it is concluded that pushover analysis is a good method for seismic performance evaluation of safe rooms. For time history analysis the 1940 El Centro, the 2003 Bam, and the 1990 Manjil earthquake records with the maximum peak accelerations of 0.35g were utilized. Also the design spectrum of Iranian Standard No. 2800-05 for the ground kind 2 is used for response spectrum analysis. The results of time history, response spectrum and pushover analyses show that the strength and displacement capacity of the steel frames are adequate to accommodate the distortions generated by seismic loads and aftershocks properly

  2. Condensing Raman spectrum for single-cell phenotype analysis

    KAUST Repository

    Sun, Shiwei

    2015-12-09

    Background In recent years, high throughput and non-invasive Raman spectrometry technique has matured as an effective approach to identification of individual cells by species, even in complex, mixed populations. Raman profiling is an appealing optical microscopic method to achieve this. To fully utilize Raman proling for single-cell analysis, an extensive understanding of Raman spectra is necessary to answer questions such as which filtering methodologies are effective for pre-processing of Raman spectra, what strains can be distinguished by Raman spectra, and what features serve best as Raman-based biomarkers for single-cells, etc. Results In this work, we have proposed an approach called rDisc to discretize the original Raman spectrum into only a few (usually less than 20) representative peaks (Raman shifts). The approach has advantages in removing noises, and condensing the original spectrum. In particular, effective signal processing procedures were designed to eliminate noise, utilising wavelet transform denoising, baseline correction, and signal normalization. In the discretizing process, representative peaks were selected to signicantly decrease the Raman data size. More importantly, the selected peaks are chosen as suitable to serve as key biological markers to differentiate species and other cellular features. Additionally, the classication performance of discretized spectra was found to be comparable to full spectrum having more than 1000 Raman shifts. Overall, the discretized spectrum needs about 5storage space of a full spectrum and the processing speed is considerably faster. This makes rDisc clearly superior to other methods for single-cell classication.

  3. Assessment of precast beam-column using capacity demand response spectrum subject to design basis earthquake and maximum considered earthquake

    Science.gov (United States)

    Ghani, Kay Dora Abd.; Tukiar, Mohd Azuan; Hamid, Nor Hayati Abdul

    2017-08-01

    Malaysia is surrounded by the tectonic feature of the Sumatera area which consists of two seismically active inter-plate boundaries, namely the Indo-Australian and the Eurasian Plates on the west and the Philippine Plates on the east. Hence, Malaysia experiences tremors from far distant earthquake occurring in Banda Aceh, Nias Island, Padang and other parts of Sumatera Indonesia. In order to predict the safety of precast buildings in Malaysia under near field ground motion the response spectrum analysis could be used for dealing with future earthquake whose specific nature is unknown. This paper aimed to develop of capacity demand response spectrum subject to Design Basis Earthquake (DBE) and Maximum Considered Earthquake (MCE) in order to assess the performance of precast beam column joint. From the capacity-demand response spectrum analysis, it can be concluded that the precast beam-column joints would not survive when subjected to earthquake excitation with surface-wave magnitude, Mw, of more than 5.5 Scale Richter (Type 1 spectra). This means that the beam-column joint which was designed using the current code of practice (BS8110) would be severely damaged when subjected to high earthquake excitation. The capacity-demand response spectrum analysis also shows that the precast beam-column joints in the prototype studied would be severely damaged when subjected to Maximum Considered Earthquake (MCE) with PGA=0.22g having a surface-wave magnitude of more than 5.5 Scale Richter, or Type 1 spectra.

  4. Research on influence of energy spectrum response of ICT detector arrays

    International Nuclear Information System (INIS)

    Zhou Rifeng; Gao Fuqiang; Zhang Ping

    2008-01-01

    The energy spectrum response is important characteristic for X-ray ICT detector. But there exist many difficulties to measure these parameters by experiments. The energy spectrum response of CdWO 4 detector was simulated by using the EGSnrc code. Meanwhile the effect of detection efficiency was analyzed by the distribution of accelerator bremsstrahlung spectra and the X-ray spectrum hardening, and some theoretic parameters were offered for the consistent and no-linearity correction of detector arrays. It was applied to ICT image correction, and a satisfying result was obtained. (authors)

  5. Systematic evaluations of probabilistic floor response spectrum generation

    International Nuclear Information System (INIS)

    Lilhanand, K.; Wing, D.W.; Tseng, W.S.

    1985-01-01

    The relative merits of the current methods for direct generation of probabilistic floor response spectra (FRS) from the prescribed design response spectra (DRS) are evaluated. The explicit probabilistic methods, which explicitly use the relationship between the power spectral density function (PSDF) and response spectra (RS), i.e., the PSDF-RS relationship, are found to have advantages for practical applications over the implicit methods. To evaluate the accuracy of the explicit methods, the root-mean-square (rms) response and the peak factor contained in the PSDF-RS relationship are systematically evaluated, especially for the narrow-band floor spectral response, by comparing the analytical results with simulation results. Based on the evaluation results, a method is recommended for practical use for the direct generation of probabilistic FRS. (orig.)

  6. Analysis of a gamma-ray spectrum by using a standard spectrum

    International Nuclear Information System (INIS)

    Tasaka, Kanji

    1975-06-01

    The standard spectrum method has been extended to take into account the energy dependence of a standard spectrum. The method analyses the observed gamma-ray spectrum by the least-square method, using an interpolated standard spectrum for expressing the line shape and a linear function for the background continuum. The interpolated standard spectrum is defined for each fitting interval by interpolating several standard spectra, which are derived directly from the observed spectra of single photopeaks each corresponding to the incident monochromatic gamma-rays by subtracting the background and smoothing the data. (author)

  7. [Analysis of salivary protease spectrum in chronic periodontitis].

    Science.gov (United States)

    Qian, Li; Xuedong, Zhou; Yaping, Fan; Tengyu, Yang; Songtao, Wu; Yu, Yu; Jiao, Chen; Ping, Zhang; Yun, Feng

    2017-02-01

    This study aimed to investigate the difference in salivary protease expression in patients with chronic periodontitis and normal individuals. The stimulating saliva in patients with chronic periodontitis and normal individuals were collected. Protein chip technology was adapted to analyze salivary protease spectrum. Among the 34 proteases in the chip, disintegrin and metalloproteinase (ADAM)8, matrix metalloproteinase (MMP)-8, MMP-12, neprilysin/CD10, and uridylyl phosphate adenosine/urokinase showed a significantly increased concentration in the saliva of chronic periodontitis patients compared with those in the saliva of normal individuals (Pchronic periodontitis patients and normal individuals significantly differed. Analysis of salivary protease spectrum is a potential clinical method to examine, diagnose, and monitor chronic periodontitis.

  8. The Spectrum Analysis Solution (SAS) System: Theoretical Analysis, Hardware Design and Implementation.

    Science.gov (United States)

    Narayanan, Ram M; Pooler, Richard K; Martone, Anthony F; Gallagher, Kyle A; Sherbondy, Kelly D

    2018-02-22

    This paper describes a multichannel super-heterodyne signal analyzer, called the Spectrum Analysis Solution (SAS), which performs multi-purpose spectrum sensing to support spectrally adaptive and cognitive radar applications. The SAS operates from ultrahigh frequency (UHF) to the S-band and features a wideband channel with eight narrowband channels. The wideband channel acts as a monitoring channel that can be used to tune the instantaneous band of the narrowband channels to areas of interest in the spectrum. The data collected from the SAS has been utilized to develop spectrum sensing algorithms for the budding field of spectrum sharing (SS) radar. Bandwidth (BW), average total power, percent occupancy (PO), signal-to-interference-plus-noise ratio (SINR), and power spectral entropy (PSE) have been examined as metrics for the characterization of the spectrum. These metrics are utilized to determine a contiguous optimal sub-band (OSB) for a SS radar transmission in a given spectrum for different modalities. Three OSB algorithms are presented and evaluated: the spectrum sensing multi objective (SS-MO), the spectrum sensing with brute force PSE (SS-BFE), and the spectrum sensing multi-objective with brute force PSE (SS-MO-BFE).

  9. Gamma spectrum analysis including NAA with SAMPO for Windows

    International Nuclear Information System (INIS)

    Aarnio, P.A.; Nikkinen, M.T.; Routti, J.T.

    1995-01-01

    SAMPO for Windows is a high performance gamma spectrum analysis program. All the measurement, analysis and NAA phases can be done either under full interactive use control or user defined tasks can be used for automated measurement and analysis sequences including control of MCAs and sample changers. High resolution gamma-ray spectroscopy together with the possibility to resolve complex multiplets with high accuracy makes SAMPO very suitable for INAA. On the other hand, the possibility to automate analysis sequences allows it use effectively also in all routine NAA measurements. NAA in SAMPO is accomplished using comparative methods. Spectra of standards, flux monitors, controls and actual samples are analyzed normally to obtain the peak areas which are optionally corrected for decay. In the comparison the flux monitor results are used to correct for variations in the effective neutron flux. An optional irradiation position correction can also be applied. The controls are used to alarm for possible deviations in the results. The sophisticated spectrum analysis methods used together with the comparative NAA and monitors give accurate results limited by the systematic effects only. The Windows environment provides ease of use and further processing power is available through the interface to expert system identification of nuclides. (author) 19 refs.; 1 tab

  10. Linearized spectrum correlation analysis for line emission measurements.

    Science.gov (United States)

    Nishizawa, T; Nornberg, M D; Den Hartog, D J; Sarff, J S

    2017-08-01

    A new spectral analysis method, Linearized Spectrum Correlation Analysis (LSCA), for charge exchange and passive ion Doppler spectroscopy is introduced to provide a means of measuring fast spectral line shape changes associated with ion-scale micro-instabilities. This analysis method is designed to resolve the fluctuations in the emission line shape from a stationary ion-scale wave. The method linearizes the fluctuations around a time-averaged line shape (e.g., Gaussian) and subdivides the spectral output channels into two sets to reduce contributions from uncorrelated fluctuations without averaging over the fast time dynamics. In principle, small fluctuations in the parameters used for a line shape model can be measured by evaluating the cross spectrum between different channel groupings to isolate a particular fluctuating quantity. High-frequency ion velocity measurements (100-200 kHz) were made by using this method. We also conducted simulations to compare LSCA with a moment analysis technique under a low photon count condition. Both experimental and synthetic measurements demonstrate the effectiveness of LSCA.

  11. Responsiveness of the Psychoeducational Profile-Third Edition for Children with Autism Spectrum Disorders

    Science.gov (United States)

    Chen, Kuan-Lin; Chiang, Fu-Mei; Tseng, Mei-Hui; Fu, Chung-Pei; Hsieh, Ching-Lin

    2011-01-01

    The aim of this study was to examine the responsiveness of the Psychoeducational Profile-third edition (PEP-3) in children with Autism Spectrum Disorders (ASD). We investigated the responsiveness in terms of three types of scores (i.e., raw scores, developmental ages, and percentile ranks) of the subtests and composites of the PEP-3 and three…

  12. Learning spectrum's selection in OLAM network for analysis cement samples

    International Nuclear Information System (INIS)

    Huang Ning; Wang Peng; Tang Daiquan; Hu Renlan

    2010-01-01

    It uses OLAM artificial neural network to analyze the samples of cement raw material. Two kinds of spectrums are used for network learning: pure-element spectrum and mix-element spectrum. The output of pure-element method can be used to construct a simulate spectrum, which can be compared with the original spectrum and judge the shift of spectrum; the mix-element method can store more message and correct the matrix effect, but the multicollinearity among spectrums can cause some side effect to the results. (authors)

  13. Spectrum analysis of hydrogen plasma in spherically convergent beam fusion

    International Nuclear Information System (INIS)

    Ogasawara, Kazuki; Yamauchi, Kunihito; Watanabe, Masato; Sunaga, Yoshitaka; Hotta, Eiki; Okino, Akitoshi

    2001-01-01

    Spectroscopic analysis of spherical glow discharge fusion device was carried out using hydrogen gas. Effects of the discharge current and cathode voltage on spectrum profiles of hydrogen Balmar lines were measured. The profiles of all hydrogen lines were broadened with the cathode voltage. From the relationship between the maximum broadening width and the cathode voltage, it was indicated that the broadening was caused by the Doppler effect. From the spatial distribution of emission intensity, it was found that plasma core size became larger with discharge current and smaller with cathode voltage. (author)

  14. Spectrum analysis of hydrogen plasma in spherically convergent beam fusion

    Energy Technology Data Exchange (ETDEWEB)

    Ogasawara, Kazuki; Yamauchi, Kunihito; Watanabe, Masato; Sunaga, Yoshitaka; Hotta, Eiki [Tokyo Institute of Technology, Dept. of Energy Sciences, Yokohama, Kanagawa (Japan); Okino, Akitoshi [Tokyo Institute of Technology, Dept. of Electrical and Electronic Engineering, Tokyo (Japan)

    2001-09-01

    Spectroscopic analysis of spherical glow discharge fusion device was carried out using hydrogen gas. Effects of the discharge current and cathode voltage on spectrum profiles of hydrogen Balmar lines were measured. The profiles of all hydrogen lines were broadened with the cathode voltage. From the relationship between the maximum broadening width and the cathode voltage, it was indicated that the broadening was caused by the Doppler effect. From the spatial distribution of emission intensity, it was found that plasma core size became larger with discharge current and smaller with cathode voltage. (author)

  15. The effect of sung speech on socio-communicative responsiveness in children with autism spectrum disorders.

    Science.gov (United States)

    Paul, Arkoprovo; Sharda, Megha; Menon, Soumini; Arora, Iti; Kansal, Nayantara; Arora, Kavita; Singh, Nandini C

    2015-01-01

    There is emerging evidence to demonstrate the efficacy of music-based interventions for improving social functioning in children with Autism Spectrum Disorders (ASD). While this evidence lends some support in favor of using song over spoken directives in facilitating engagement and receptive intervention in ASD, there has been little research that has investigated the efficacy of such stimuli on socio-communicative responsiveness measures. Here, we present preliminary results from a pilot study which tested whether sung instruction, as compared to spoken directives, could elicit greater number of socio-communicative behaviors in young children with ASD. Using an adapted single-subject design, three children between the ages of 3 and 4 years, participated in a programme consisting of 18 sessions, of which 9 were delivered with spoken directives and 9 with sung. Sessions were counterbalanced and randomized for three play activities-block matching, picture matching and clay play. All sessions were video-recorded for post-hoc observational coding of three behavioral metrics which included performance, frequency of social gesture and eye contact. Analysis of the videos by two independent raters indicated increased socio-communicative responsiveness in terms of frequency of social gesture as well as eye contact during sung compared to spoken conditions, across all participants. Our findings suggest that sung directives may play a useful role in engaging children with ASD and also serve as an effective interventional medium to enhance socio-communicative responsiveness.

  16. The effect of sung speech on socio-communicative responsiveness in children with Autism Spectrum Disorders

    Directory of Open Access Journals (Sweden)

    Arkoprovo ePaul

    2015-10-01

    Full Text Available There is emerging evidence to demonstrate the efficacy of music based interventions for improving social functioning in children with Autism Spectrum Disorders (ASD. While this evidence lends some support in favour of using song over spoken directives in facilitating engagement and receptive intervention in ASD, there has been little research that has investigated the efficacy of such stimuli on socio-communicative responsiveness measures. Here, we present preliminary results from a pilot study which tested whether sung instruction, as compared to spoken directives, could elicit greater number of socio-communicative behaviours in young children with ASD. Using an adapted single-subject design, three children between the ages of 3 and 4 years, participated in a programme consisting of 18 sessions, of which 9 were delivered with spoken directives and 9 with sung. Sessions were counterbalanced and randomized for three play activities - block matching, picture matching and clay play. All sessions were video-recorded for post-hoc observational coding of three behavioural metrics which included performance, frequency of social gesture and eye contact. Analysis of the videos by two independent raters indicated increased socio-communicative responsiveness in terms of frequency of social gesture as well as eye contact during sung compared to spoken conditions across all participants. Our findings suggest that sung directives may play a useful role in engaging children with ASD and also serve as an effective interventional medium to enhance socio-communicative responsiveness.

  17. Performance analysis of distributed beamforming in a spectrum sharing system

    KAUST Repository

    Yang, Liang

    2013-05-01

    In this paper, we consider a distributed beamforming scheme (DBF) in a spectrum sharing system where multiple secondary users share the spectrum with some licensed primary users under an interference temperature constraint. We assume that the DBF is applied at the secondary users. We first consider optimal beamforming and compare it with the user selection scheme in terms of the outage probability and bit error rate performance metrics. Since perfect feedback is difficult to obtain, we then investigate a limited feedback DBF scheme and develop an analysis for a random vector quantization design algorithm. Specifically, the approximate statistics functions of the squared inner product between the optimal and quantized vectors are derived. With these statistics, we analyze the outage performance. Furthermore, the effects of channel estimation error and number of primary users on the system performance are investigated. Finally, optimal power adaptation and cochannel interference are considered and analyzed. Numerical and simulation results are provided to illustrate our mathematical formalism and verify our analysis. © 2012 IEEE.

  18. Comparison of Shock Response Spectrum for Different Gun Tests

    Directory of Open Access Journals (Sweden)

    J.A. Cordes

    2013-01-01

    Full Text Available The Soft Catch Gun at Picatinny Arsenal is regularly used for component testing. Most shots contain accelerometers which record accelerations as a function of time. Statistics of accelerometer data indicate that the muzzle exit accelerations are, on average, higher than tactical firings. For that reason, Soft Catch Gun tests with unusually high accelerations may not be scored for Lot Acceptance Tests (LAT by some customers. The 95/50 Normal Tolerance Limit (NTL is proposed as a means of determining which test results should be scored. This paper presents comparisons of Shock Response Spectra (SRS used for the 95/50 scoring criteria. The paper also provides a Discussion Section outlining some concerns with scoring LAT results based on test results outside of the proposed 95/50 criteria.

  19. Error evaluation of inelastic response spectrum method for earthquake design

    International Nuclear Information System (INIS)

    Paz, M.; Wong, J.

    1981-01-01

    Two-story, four-story and ten-story shear building-type frames subjected to earthquake excitaion, were analyzed at several levels of their yield resistance. These frames were subjected at their base to the motion recorded for north-south component of the 1940 El Centro earthquake, and to an artificial earthquake which would produce the response spectral charts recommended for design. The frames were first subjected to 25% or 50% of the intensity level of these earthquakes. The resulting maximum relative displacement for each story of the frames was assumed to be yield resistance for the subsequent analyses at 100% of intensity for the excitation. The frames analyzed were uniform along their height with the stiffness adjusted as to result in 0.20 seconds of the fundamental period for the two-story frame, 0.40 seconds for the four-story frame and 1.0 seconds for the ten-story frame. Results of the study provided the following conclusions: (1) The percentage error in floor displacement for linear behavior was less than 10%; (2) The percentage error in floor displacement for inelastic behavior (elastoplastic) could be as high as 100%; (3) In most of the cases analyzed, the error increased with damping in the system; (4) As a general rule, the error increased as the modal yield resistance decreased; (5) The error was lower for the structures subjected to the 1940 E1 Centro earthquake than for the same structures subjected to an artificial earthquake which was generated from the response spectra for design. (orig./HP)

  20. Analyzing Chaos Systems and Fine Spectrum Sensing Using Detrended Fluctuation Analysis Algorithm

    Directory of Open Access Journals (Sweden)

    Javier S. González-Salas

    2016-01-01

    Full Text Available A numerical study that uses detrended fluctuation analysis (DFA algorithm of time series obtained from linear and nonlinear dynamical systems is presented. The DFA algorithm behavior toward periodic and chaotic signals is investigated and the effect of the time scale under analysis is discussed. The displayed results prove that the DFA algorithm response is invariant (stable performance to initial condition and chaotic system parameters. An initial idea of DFA algorithm implementation for fine spectrum sensing (SS is proposed under two-stage spectrum sensor approach with test statistics based on the scaling exponent value. The outcomes demonstrate a promising new SS technique that can alleviate several imperfections such as noise power uncertainty and spatial correlation between the adjacent antenna array elements.

  1. Estimating Driving Performance Based on EEG Spectrum Analysis

    Directory of Open Access Journals (Sweden)

    Jung Tzyy-Ping

    2005-01-01

    Full Text Available The growing number of traffic accidents in recent years has become a serious concern to society. Accidents caused by driver's drowsiness behind the steering wheel have a high fatality rate because of the marked decline in the driver's abilities of perception, recognition, and vehicle control abilities while sleepy. Preventing such accidents caused by drowsiness is highly desirable but requires techniques for continuously detecting, estimating, and predicting the level of alertness of drivers and delivering effective feedbacks to maintain their maximum performance. This paper proposes an EEG-based drowsiness estimation system that combines electroencephalogram (EEG log subband power spectrum, correlation analysis, principal component analysis, and linear regression models to indirectly estimate driver's drowsiness level in a virtual-reality-based driving simulator. Our results demonstrated that it is feasible to accurately estimate quantitatively driving performance, expressed as deviation between the center of the vehicle and the center of the cruising lane, in a realistic driving simulator.

  2. Nuclear analysis software. Pt. 2: Gamma spectrum analysis, activity calculations and neutron activiation analysis (GANAAS)

    International Nuclear Information System (INIS)

    1991-01-01

    A spectrum acquired with a multichannel analyzer is usually stored with a suitable device (tape, cassette tape, diskette, hard disk). Every manufacturer of multichannel analyzers uses his own method for storage, and records the spectra in his own format. Furthermore, the formats to save the spectra evolve in time: the same manufacturer can have several formats for different generations of multichannel analyzers. A similar situation prevails with the spectrum analysis programmes. They require spectra in a particular format as the input to the analysis. Again, these input formats are many and differ from each other considerably. SPEDAC set of routines was developed to provide the spectroscopist with a tool for converting the spectral formats. They can read the spectra recorded in a number of formats used in different multichannel analyzers, to a number of analysis programmes. In fact, all the major formats are represented. Another serious problem for the user of a stand-alone multichannel analyzer is the transfer of spectra from the MCA to the computer. For several well known types of MCAs, the Version 5.0 of SPEDAC offers a set of routines for spectrum transfer, using the most simple methods of interfacing. All the transfer programmes described in this manual have been carefully tested with the corresponding stand-alone multichannel analyzers

  3. Singular spectrum analysis of sleep EEG in insomnia.

    Science.gov (United States)

    Aydın, Serap; Saraoǧlu, Hamdi Melih; Kara, Sadık

    2011-08-01

    In the present study, the Singular Spectrum Analysis (SSA) is applied to sleep EEG segments collected from healthy volunteers and patients diagnosed by either psycho physiological insomnia or paradoxical insomnia. Then, the resulting singular spectra computed for both C3 and C4 recordings are assigned as the features to the Artificial Neural Network (ANN) architectures for EEG classification in diagnose. In tests, singular spectrum of particular sleep stages such as awake, REM, stage1 and stage2, are considered. Three clinical groups are successfully classified by using one hidden layer ANN architecture with respect to their singular spectra. The results show that the SSA can be applied to sleep EEG series to support the clinical findings in insomnia if ten trials are available for the specific sleep stages. In conclusion, the SSA can detect the oscillatory variations on sleep EEG. Therefore, different sleep stages meet different singular spectra. In addition, different healthy conditions generate different singular spectra for each sleep stage. In summary, the SSA can be proposed for EEG discrimination to support the clinical findings for psycho-psychological disorders.

  4. Instantaneous response spectrum in seismic testing of nuclear power plant equipment

    International Nuclear Information System (INIS)

    Morrone, A.

    1977-01-01

    This paper presents the concept of instantaneous response spectrum (IRS) as the response of single degree of freedom oscillators at a particular time. It demonstrates that a shake table random motion whose standard TRS envelops the RRS does not necessarily satisfy the enveloping requirement instantaneously. That is, any one (or more) instantaneous required response spectrum (IRRS) is not enveloped by any instantaneous test response spectrum (ITRS). Response spectra from different time histories, including single frequency sine beat motion used in resonance testing, are compared for enveloping with maximum response and with the actual response at particular times. These comparisons are given for the enveloping of RRS and IRRS derived with a time history response calculated at a particular building elevation of a nuclear power plant. For the test motion, several of the most severe ITRS derived with a modified EL Centro motion and with a sine beat motion with ten cycles per beat were used. It is shown that although the TRS with the modified EL Centro motion enveloped the given RRS, the selected modified EL Centro ITRS did not envelop the corresponding IRRS. With the sine beat motion, even though the TRS did not fully envelop the given RRS, the resulting sine beat ITRS did not require a larger factor for full IRRS enveloping than those of the modified EL Centro motion

  5. Wind speed power spectrum analysis for Bushland, Texas

    Energy Technology Data Exchange (ETDEWEB)

    Eggleston, E.D. [USDA-Agricultural Research Service, Bushland, TX (United States)

    1996-12-31

    Numerous papers and publications on wind turbulence have referenced the wind speed spectrum presented by Isaac Van der Hoven in his article entitled Power Spectrum of Horizontal Wind Speed Spectrum in the Frequency Range from 0.0007 to 900 Cycles per Hour. Van der Hoven used data measured at different heights between 91 and 125 meters above the ground, and represented the high frequency end of the spectrum with data from the peak hour of hurricane Connie. These facts suggest we should question the use of his power spectrum in the wind industry. During the USDA - Agricultural Research Service`s investigation of wind/diesel system power storage, using the appropriate wind speed power spectrum became a significant issue. We developed a power spectrum from 13 years of hourly average data, 1 year of 5 minute average data, and 2 particularly gusty day`s 1 second average data all collected at a height of 10 meters. While the general shape is similar to the Van der Hoven spectrum, few of his peaks were found in the Bushland spectrum. While higher average wind speeds tend to suggest higher amplitudes in the high frequency end of the spectrum, this is not always true. Also, the high frequency end of the spectrum is not accurately described by simple wind statistics such as standard deviation and turbulence intensity. 2 refs., 5 figs., 1 tab.

  6. Multichannel singular spectrum analysis of the axial atmospheric angular momentum

    Directory of Open Access Journals (Sweden)

    Leonid Zotov

    2017-11-01

    Full Text Available Earth's variable rotation is mainly produced by the variability of the AAM (atmospheric angular momentum. In particular, the axial AAM component χ3, which undergoes especially strong variations, induces changes in the Earth's rotation rate. In this study we analysed maps of regional input into the effective axial AAM from 1948 through 2011 from NCEP/NCAR reanalysis. Global zonal circulation patterns related to the LOD (length of day were described. We applied MSSA (Multichannel Singular Spectrum Analysis jointly to the mass and motion components of AAM, which allowed us to extract annual, semiannual, 4-month, quasi-biennial, 5-year, and low-frequency oscillations. PCs (Principal components strongly related to ENSO (El Nino southern oscillation were released. They can be used to study ENSO-induced changes in pressure and wind fields and their coupling to LOD. The PCs describing the trends have captured slow atmospheric circulation changes possibly related to climate variability.

  7. Pattern Recognition of Gene Expression with Singular Spectrum Analysis

    Directory of Open Access Journals (Sweden)

    Hossein Hassani

    2014-07-01

    Full Text Available Drosophila segmentation as a model organism is one of the most highly studied. Among many maternal segmentation coordinate genes, bicoid protein pattern plays a significant role during Drosophila embryogenesis, since this gradient determines most aspects of head and thorax development. Despite the fact that several models have been proposed to describe the bicoid gradient, due to its association with considerable error, each can only partially explain bicoid characteristics. In this paper, a modified version of singular spectrum analysis is examined for filtering and extracting the bicoid gene expression signal. The results with strong evidence indicate that the proposed technique is able to remove noise more effectively and can be considered as a promising method for filtering gene expression measurements for other applications.

  8. Response Inhibition in Adults with Autism Spectrum Disorder Compared to Attention Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Johnston, Kate; Madden, Anya K.; Bramham, Jessica; Russell, Ailsa J.

    2011-01-01

    Autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) are hypothesised to involve core deficits in executive function. Previous studies have found evidence of a double dissociation between the disorders on specific executive functions (planning and response inhibition). To date most research has been conducted with…

  9. Neuromagnetic Oscillations Predict Evoked-Response Latency Delays and Core Language Deficits in Autism Spectrum Disorders

    Science.gov (United States)

    Edgar, J. Christopher; Khan, Sarah Y.; Blaskey, Lisa; Chow, Vivian Y.; Rey, Michael; Gaetz, William; Cannon, Katelyn M.; Monroe, Justin F.; Cornew, Lauren; Qasmieh, Saba; Liu, Song; Welsh, John P.; Levy, Susan E.; Roberts, Timothy P. L.

    2015-01-01

    Previous studies have observed evoked response latency as well as gamma band superior temporal gyrus (STG) auditory abnormalities in individuals with autism spectrum disorders (ASD). A limitation of these studies is that associations between these two abnormalities, as well as the full extent of oscillatory phenomena in ASD in terms of frequency…

  10. Spectrum response estimation for deep-water floating platforms via retardation function representation

    Science.gov (United States)

    Liu, Fushun; Liu, Chengcheng; Chen, Jiefeng; Wang, Bin

    2017-08-01

    The key concept of spectrum response estimation with commercial software, such as the SESAM software tool, typically includes two main steps: finding a suitable loading spectrum and computing the response amplitude operators (RAOs) subjected to a frequency-specified wave component. In this paper, we propose a nontraditional spectrum response estimation method that uses a numerical representation of the retardation functions. Based on estimated added mass and damping matrices of the structure, we decompose and replace the convolution terms with a series of poles and corresponding residues in the Laplace domain. Then, we estimate the power density corresponding to each frequency component using the improved periodogram method. The advantage of this approach is that the frequency-dependent motion equations in the time domain can be transformed into the Laplace domain without requiring Laplace-domain expressions for the added mass and damping. To validate the proposed method, we use a numerical semi-submerged pontoon from the SESAM. The numerical results show that the responses of the proposed method match well with those obtained from the traditional method. Furthermore, the estimated spectrum also matches well, which indicates its potential application to deep-water floating structures.

  11. Incident spectrum determination for time-of-flight neutron powder diffraction data analysis

    International Nuclear Information System (INIS)

    Hodges, J. P.

    1998-01-01

    Accurate characterization of the incident neutron spectrum is an important requirement for precise Rietveld analysis of time-of-flight powder neutron diffraction data. Without an accurate incident spectrum the calculated model for the measured relative intensities of individual Bragg reflections will possess systematic errors. We describe a method for obtaining an accurate numerical incident spectrum using data from a transmitted beam monitor

  12. A survey of genomic studies supports association of circadian clock genes with bipolar disorder spectrum illnesses and lithium response.

    Directory of Open Access Journals (Sweden)

    Michael J McCarthy

    Full Text Available Circadian rhythm abnormalities in bipolar disorder (BD have led to a search for genetic abnormalities in circadian "clock genes" associated with BD. However, no significant clock gene findings have emerged from genome-wide association studies (GWAS. At least three factors could account for this discrepancy: complex traits are polygenic, the organization of the clock is more complex than previously recognized, and/or genetic risk for BD may be shared across multiple illnesses. To investigate these issues, we considered the clock gene network at three levels: essential "core" clock genes, upstream circadian clock modulators, and downstream clock controlled genes. Using relaxed thresholds for GWAS statistical significance, we determined the rates of clock vs. control genetic associations with BD, and four additional illnesses that share clinical features and/or genetic risk with BD (major depression, schizophrenia, attention deficit/hyperactivity. Then we compared the results to a set of lithium-responsive genes. Associations with BD-spectrum illnesses and lithium-responsiveness were both enriched among core clock genes but not among upstream clock modulators. Associations with BD-spectrum illnesses and lithium-responsiveness were also enriched among pervasively rhythmic clock-controlled genes but not among genes that were less pervasively rhythmic or non-rhythmic. Our analysis reveals previously unrecognized associations between clock genes and BD-spectrum illnesses, partly reconciling previously discordant results from past GWAS and candidate gene studies.

  13. Nuclear analysis software. Pt. 1: Spectrum transfer and reformatting (SPEDAC)

    International Nuclear Information System (INIS)

    1991-01-01

    GANAAS (Gamma, Activity, and Neutron Activation Analysis System) is one in the family of software packages developed under the auspices of the International Atomic Energy Agency. Primarily, the package was intended to support the IAEA Technical Assistance and Cooperation projects in developing countries. However, it is open domain software that can be copied and used by anybody, except for commercial purposes. All the nuclear analysis software provided by the IAEA has the same design philosophy and similar structure. The intention was to provide the user with maximum flexibility, at the same time with a simple and logical organization that requires minimum digging through the manuals. GANAAS is a modular system. It consists of several programmes that can be installed on the hard disk as the are needed. Obviously, some parts of they system are required in all cases. Those are installed at the beginning, without consulting the operator. GANAAS offers the opportunity to expand and improve the system. The gamma spectrum evaluation programmes using different fitting algorithms can be added to GANAAS, under the condition that the format of their input and output files corresponds to the rules of GANAAS. The same applies to the quantitative analysis parts of the programme

  14. Time-dependent spectrum analysis of high power gyrotrons

    International Nuclear Information System (INIS)

    Schlaich, Andreas

    2015-01-01

    In this work, an investigation of vacuum electronic oscillators capable of generating multi-megawatt continuous wave output power in the millimeter-wave range (so-called gyrotrons) through spectral measurements is presented. The centerpiece is the development of a measurement system with a high dynamic range (50-60 dB) for time-dependent spectrum analysis, covering the frequency range 100-170 GHz with instantaneous bandwidths of 6-12 GHz. Despite relying on heterodyne reception through harmonic mixers, the Pulse Spectrum Analysis (PSA) system maintains RF unambiguity in the spectrogram output through the application of a novel RF reconstruction technique. Using the new possibilities, a wide range of spectral phenomena in gyrotrons has been investigated, such as cavity mode jumps, lowfrequency modulation, frequency tuning in long pulses and the spectral behavior during the presence of an RF window arc. A dedicated investigation on parasitic RF oscillations in W7-X gyrotrons combining several analysis techniques led to the conclusion that after-cavity oscillations can be physical reality in high power gyrotrons, and are the probable cause for the undesired signals observed. Apart from systematic parameter sweeps using the PSA system, an analytical dispersion analysis in the Brillouin diagram was applied, and numerical gyrotron interaction simulations of unprecedented extent were conducted. Furthermore, the improved frequency measurement capabilities were employed to analyze the frequency tuning through thermal expansion and electrostatic neutralization caused by ionization inside the tube in long-pulse operation. By macroscopically modeling the gas dynamics and ionization processes in combination with a fitting process, the time dependences of the two processes could be investigated. In doing so, indication was found that the neutralization in W7-X gyrotrons amounts to only 60% of the electrostatic depression voltage, instead of 100% as widely believed for

  15. Time-dependent spectrum analysis of high power gyrotrons

    Energy Technology Data Exchange (ETDEWEB)

    Schlaich, Andreas

    2015-07-01

    In this work, an investigation of vacuum electronic oscillators capable of generating multi-megawatt continuous wave output power in the millimeter-wave range (so-called gyrotrons) through spectral measurements is presented. The centerpiece is the development of a measurement system with a high dynamic range (50-60 dB) for time-dependent spectrum analysis, covering the frequency range 100-170 GHz with instantaneous bandwidths of 6-12 GHz. Despite relying on heterodyne reception through harmonic mixers, the Pulse Spectrum Analysis (PSA) system maintains RF unambiguity in the spectrogram output through the application of a novel RF reconstruction technique. Using the new possibilities, a wide range of spectral phenomena in gyrotrons has been investigated, such as cavity mode jumps, lowfrequency modulation, frequency tuning in long pulses and the spectral behavior during the presence of an RF window arc. A dedicated investigation on parasitic RF oscillations in W7-X gyrotrons combining several analysis techniques led to the conclusion that after-cavity oscillations can be physical reality in high power gyrotrons, and are the probable cause for the undesired signals observed. Apart from systematic parameter sweeps using the PSA system, an analytical dispersion analysis in the Brillouin diagram was applied, and numerical gyrotron interaction simulations of unprecedented extent were conducted. Furthermore, the improved frequency measurement capabilities were employed to analyze the frequency tuning through thermal expansion and electrostatic neutralization caused by ionization inside the tube in long-pulse operation. By macroscopically modeling the gas dynamics and ionization processes in combination with a fitting process, the time dependences of the two processes could be investigated. In doing so, indication was found that the neutralization in W7-X gyrotrons amounts to only 60% of the electrostatic depression voltage, instead of 100% as widely believed for

  16. Seismic response analysis of structural system subjected to multiple support excitation

    International Nuclear Information System (INIS)

    Wu, R.W.; Hussain, F.A.; Liu, L.K.

    1978-01-01

    In the seismic analysis of a multiply supported structural system subjected to nonuniform excitations at each support point, the single response spectrum, the time history, and the multiple response spectrum are the three commonly employed methods. In the present paper the three methods are developed, evaluated, and the limitations and advantages of each method assessed. A numerical example has been carried out for a typical piping system. Considerably smaller responses have been predicted by the time history method than that by the single response spectrum method. This is mainly due to the fact that the phase and amplitude relations between the support excitations are faithfully retained in the time history method. The multiple response spectrum prediction has been observed to compare favourably with the time history method prediction. Based on the present evaluation, the multiple response spectrum method is the most efficient method for seismic response analysis of structural systems subjected to multiple support excitation. (Auth.)

  17. Brain Responses Underlying Anthropomorphism, Agency, and Social Attribution in Autism Spectrum Disorder.

    Science.gov (United States)

    Ammons, Carla J; Doss, Constance F; Bala, David; Kana, Rajesh K

    2018-01-01

    Theory of Mind (ToM), the ability to attribute mental states to oneself and others, is frequently impaired in Autism Spectrum Disorder (ASD) and may result from altered activation of social brain regions. Conversely, Typically Developing (TD) individuals overextend ToM and show a strong tendency to anthropomorphize and interpret biological motion in the environment. Less is known about how the degree of anthropomorphism influences intentional attribution and engagement of the social brain in ASD. This fMRI study examines the extent of anthropomorphism, its role in social attribution, and the underlying neural responses in ASD and TD using a series of human stick figures and geometrical shapes. 14 ASD and 14 TD adults watched videos of stick figures and triangles interacting in random or socially meaningful ways while in an fMRI scanner. In addition, they completed out-of-scanner measures of ToM skill and real-world social deficits. Whole brain statistical analysis was performed for regression and within and between group comparisons of all conditions using SPM12's implementation of the general linear model. ToM network regions were activated in response to social movement and human-like characters in ASD and TD. In addition, greater ToM ability was associated with increased TPJ and MPFC activity while watching stick figures; whereas more severe social symptoms were associated with reduced right TPJ activation in response to social movement. These results suggest that degree of anthropomorphism does not differentially affect social attribution in ASD and highlights the importance of TPJ in ToM and social attribution.

  18. Frequency spectrum analysis of 252Cf neutron source based on LabVIEW

    International Nuclear Information System (INIS)

    Mi Deling; Li Pengcheng

    2011-01-01

    The frequency spectrum analysis of 252 Cf Neutron source is an extremely important method in nuclear stochastic signal processing. Focused on the special '0' and '1' structure of neutron pulse series, this paper proposes a fast-correlation algorithm to improve the computational rate of the spectrum analysis system. And the multi-core processor technology is employed as well as multi-threaded programming techniques of LabVIEW to construct frequency spectrum analysis system of 252 Cf neutron source based on LabVIEW. It not only obtains the auto-correlation and cross correlation results, but also auto-power spectrum,cross-power spectrum and ratio of spectral density. The results show that: analysis tools based on LabVIEW improve the fast auto-correlation and cross correlation code operating efficiency about by 25% to 35%, also verify the feasibility of using LabVIEW for spectrum analysis. (authors)

  19. Universal spectrum data analysis program for microsoft windows

    International Nuclear Information System (INIS)

    Hao, F.; Cai, Z.; Wang, H.

    1993-01-01

    We have developed a universal spectrum analysis and characterization program the Microsoft Windows environment. This sophisticated and easy to use software package can be employed in many areas for spectra data analysis, parametrization and line profile recognition. Spectra can for example be smoothed, calibrated and transformed from the laboratory frame to the projectile frame and background can be subtracted by using cubic spline functions or exponential functions. Up to 10 peaks and 40 different parameters can be fitted simultaneously either automatically by least squares routines or manually by system interactive devices. Line profiles include triangular, Gaussian, Lorentzian, Fano, Shore, post collisonal interactions functions etc., and also can be easily expanded to virtually any nonlinear fitting function. In addition, Fast Fourier Transform (FFT) routines allow users to convolute, deconvolute or Fourier analyze complex spectral patterns. Specifically this program has been applied for high resolution electron- and photon emission spectra following electron or ion collision with gaseous targets. Some examples for data evaluation will be presented

  20. Evaluation of peak-fitting software for gamma spectrum analysis

    International Nuclear Information System (INIS)

    Zahn, Guilherme S.; Genezini, Frederico A.; Moralles, Mauricio

    2009-01-01

    In all applications of gamma-ray spectroscopy, one of the most important and delicate parts of the data analysis is the fitting of the gamma-ray spectra, where information as the number of counts, the position of the centroid and the width, for instance, are associated with each peak of each spectrum. There's a huge choice of computer programs that perform this type of analysis, and the most commonly used in routine work are the ones that automatically locate and fit the peaks; this fit can be made in several different ways - the most common ways are to fit a Gaussian function to each peak or simply to integrate the area under the peak, but some software go far beyond and include several small corrections to the simple Gaussian peak function, in order to compensate for secondary effects. In this work several gamma-ray spectroscopy software are compared in the task of finding and fitting the gamma-ray peaks in spectra taken with standard sources of 137 Cs, 60 Co, 133 Ba and 152 Eu. The results show that all of the automatic software can be properly used in the task of finding and fitting peaks, with the exception of GammaVision; also, it was possible to verify that the automatic peak-fitting software did perform as well as - and sometimes even better than - a manual peak-fitting software. (author)

  1. Capacity analysis of spectrum sharing spatial multiplexing MIMO systems

    KAUST Repository

    Yang, Liang

    2014-12-01

    This paper considers a spectrum sharing (SS) multiple-input multiple-output (MIMO) system operating in a Rayleigh fading environment. First the capacity of a single-user SS spatial multiplexing system is investigated in two scenarios that assume different receivers. To explicitly show the capacity scaling law of SS MIMO systems, some approximate capacity expressions for the two scenarios are derived. Next, we extend our analysis to a multiple user system with zero-forcing receivers (ZF) under spatially-independent scheduling and analyze the sum-rate. Furthermore, we provide an asymptotic sum-rate analysis to investigate the effects of different parameters on the multiuser diversity gain. Our results show that the secondary system with a smaller number of transmit antennas Nt and a larger number of receive antennas Nr can achieve higher capacity at lower interference temperature Q, but at high Q the capacity follows the scaling law of the conventional MIMO systems. However, for a ZF SS spatial multiplexing system, the secondary system with small Nt and large Nr can achieve the highest capacity throughout the entire region of Q. For a ZF SS spatial multiplexing system with scheduling, the asymptotic sum-rate scales like Ntlog2(Q(KNtNp-1)/Nt), where Np denotes the number of antennas of the primary receiver and K represents the number of secondary transmitters.

  2. Assessing the Accuracy of the Modified Chinese Autism Spectrum Rating Scale and Social Responsiveness Scale for Screening Autism Spectrum Disorder in Chinese Children

    Institute of Scientific and Technical Information of China (English)

    Bingrui Zhou; Hao Zhou; Lijie Wu; Xiaobing Zou; Xuerong Luo; Eric Fombonne; Yi Wang; Weili Yan; Xiu Xu

    2017-01-01

    The reported prevalence of autism spectrum disorder (ASD) has been increasing rapidly in many parts of the world.However,data on its prevalence in China are largely missing.Here,we assessed the suitability of the modified Chinese version of a newly-developed ASD screening tool,the Modified Chinese Autism Spectrum Rating Scales (MC-ASRS) in screening for ASD in Chinese children aged 6-12 years,through comparison with the Social Responsiveness Scale (SRS) that has been widely used for ASD screening.We recruited the parents/caregivers of 1588 typically-developing children and 190 children with ASD aged 6-12 years to complete the MC-ASRS and SRS,and evaluated the validity of both scales in discriminating children with ASD from those developing typically.The results showed that MC-ASRS performed as well as SRS in sensitivity,specificity,and area-under-the-curve (both >0.95) in receiver operating characteristic analysis,with a fair false-negative rate.These results suggest that MC-ASRS is a promising tool for screening for children with ASD in the general Chinese population.

  3. 78 FR 31568 - Proposed Collection; 60-day Comment Request: Autism Spectrum Disorder Research Portfolio Analysis

    Science.gov (United States)

    2013-05-24

    ... Comment Request: Autism Spectrum Disorder Research Portfolio Analysis SUMMARY: In compliance with the.... Proposed Collection: Autism Spectrum Disorder (ASD) Research Portfolio Analysis, 0925--NEW--National... Collection: The purpose of the ASD portfolio analysis is to collect research funding data from U.S. and...

  4. Multi-spectrum and transmit-antenna switched diversity schemes for spectrum sharing systems: A performance analysis

    KAUST Repository

    Sayed, Mostafa

    2012-12-01

    In spectrum sharing systems, a secondary user (SU) is allowed to share the spectrum with a primary licensed user under the condition that the interference at the the primary user receiver (PU-Rx) is below a predetermined threshold. Joint primary spectrum and transmit antenna selection diversity schemes can be utilized as an efficient way to meet the quality of service (QoS) demands of the SUs while satisfying the interference constraint. In this paper, we consider a secondary link comprised of a secondary transmitter (SU-Tx) equipped with multiple antennas and a single-antenna secondary receiver (SU-Rx) sharing the same spectrum with a number of primary users (PUs) operating at distinct spectra. We present a performance analysis for two primary spectrum and transmit antenna switched selection schemes with different amount of feedback requirements. In particular, assuming Rayleigh fading and BPSK transmission, we derive approximate BER expressions for the presented schemes. For the sake of comparison, we also derive a closed-form BER expression for the optimal selection scheme that selects the best pair in terms of the SU-Rx signal-to-noise ratio (SNR) which has the disadvantage of high feedback requirements. Finally, our results are verified with numerical simulations. © 2012 IEEE.

  5. Estimating 2-D Vector Velocities Using Multidimensional Spectrum Analysis

    DEFF Research Database (Denmark)

    Oddershede, Niels; Løvstakken, Lasse; Torp, Hans

    2008-01-01

    new velocity estimators for finding both the axial and lateral velocity components. The estimators essentially search for the plane in the 3-D Fourier space, where the integrated power spectrum is largest. The first uses the 3-D Fourier transform to find the power spectrum, while the second uses...

  6. Condensing Raman spectrum for single-cell phenotype analysis

    KAUST Repository

    Sun, Shiwei; Wang, Xuetao; Gao, Xin; Ren, Lihui; Su, Xiaoquan; Bu, Dongbo; Ning, Kang

    2015-01-01

    In this work, we have proposed an approach called rDisc to discretize the original Raman spectrum into only a few (usually less than 20) representative peaks (Raman shifts). The approach has advantages in removing noises, and condensing the original spectrum. In particular, effective signal processing procedures were designed to eliminate noise, utilising wavelet transform denoising, baseline correction, and signal normalization. In the discretizing process, representative peaks were selected to signicantly decrease the Raman data size. More importantly, the selected peaks are chosen as suitable to serve as key biological markers to differentiate species and other cellular features. Additionally, the classication performance of discretized spectra was found to be comparable to full spectrum having more than 1000 Raman shifts. Overall, the discretized spectrum needs about 5storage space of a full spectrum and the processing speed is considerably faster. This makes rDisc clearly superior to other methods for single-cell classication.

  7. Impact induced response spectrum for the safety evaluation of the high flux isotope reactor

    International Nuclear Information System (INIS)

    Chang, S.J.

    1997-01-01

    The dynamic impact to the nearby HFIR reactor vessel caused by heavy load drop is analyzed. The impact calculation is carried out by applying the ABAQUS computer code. An impact-induced response spectrum is constructed in order to evaluate whether the HFIR vessel and the shutdown mechanism may be disabled. For the frequency range less than 10 Hz, the maximum spectral velocity of impact is approximately equal to that of the HFIR seismic design-basis spectrum. For the frequency range greater than 10 Hz, the impact-induced response spectrum is shown to cause no effect to the control rod and the shutdown mechanism. An earlier seismic safety assessment for the HFIR control and shutdown mechanism was made by EQE. Based on EQE modal solution that is combined with the impact-induced spectrum, it is concluded that the impact will not cause any damage to the shutdown mechanism, even while the reactor is in operation. The present method suggests a general approach for evaluating the impact induced damage to the reactor by applying the existing finite element modal solution that has been carried out for the seismic evaluation of the reactor

  8. Spectrum image analysis tool - A flexible MATLAB solution to analyze EEL and CL spectrum images.

    Science.gov (United States)

    Schmidt, Franz-Philipp; Hofer, Ferdinand; Krenn, Joachim R

    2017-02-01

    Spectrum imaging techniques, gaining simultaneously structural (image) and spectroscopic data, require appropriate and careful processing to extract information of the dataset. In this article we introduce a MATLAB based software that uses three dimensional data (EEL/CL spectrum image in dm3 format (Gatan Inc.'s DigitalMicrograph ® )) as input. A graphical user interface enables a fast and easy mapping of spectral dependent images and position dependent spectra. First, data processing such as background subtraction, deconvolution and denoising, second, multiple display options including an EEL/CL moviemaker and, third, the applicability on a large amount of data sets with a small work load makes this program an interesting tool to visualize otherwise hidden details. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Evaluation of the Neutron Detector Response for Cosmic Ray Energy Spectrum by Monte Carlo Transport Simulation

    International Nuclear Information System (INIS)

    Pazianotto, Mauricio T.; Carlson, Brett V.; Federico, Claudio A.; Gonzalez, Odair L.

    2011-01-01

    Neutrons generated by the interaction of cosmic rays with the atmosphere make an important contribution to the dose accumulated in electronic circuits and aircraft crew members at flight altitude. High-energy neutrons are produced in spallation reactions and intranuclear cascade processes by primary cosmic-ray particle interactions with atoms in the atmosphere. These neutrons can produce secondary neutrons and also undergo a moderation process due to atmosphere interactions, resulting in a wider energy spectrum, ranging from thermal energies (0.025 eV) to energies of several hundreds of MeV. The Long-Counter (LC) detector is a widely used neutron detector designed to measure the directional flux of neutrons with about constant response over a wide energy range (thermal to 20 MeV). ). Its calibration process and the determination of its energy response for the wide-energy of cosmic ray induced neutron spectrum is a very difficult process due to the lack of installations with these capabilities. The goal of this study is to assess the behavior of the response of a Long Counter using the Monte Carlo (MC) computational code MCNPX (Monte Carlo N-Particle eXtended). The dependence of the Long Counter response on the angle of incidence, as well as on the neutron energy, will be carefully investigated, compared with the experimental data previously obtained with 241 Am-Be and 252 Cf neutron sources and extended to the neutron spectrum produced by cosmic rays. (Author)

  10. Empathic responsiveness of children and adolescents with high-functioning autism spectrum disorder.

    Science.gov (United States)

    Scheeren, Anke M; Koot, Hans M; Mundy, Peter C; Mous, Larissa; Begeer, Sander

    2013-10-01

    Previous studies have shown reduced empathic responsiveness to others' emotions in preschoolers with autism spectrum disorder (ASD) and an intellectual disability. However, age and intelligence may promote children's empathic responsiveness. Therefore, we examined the empathic responsiveness in normally intelligent school-aged children and adolescents with a clinical diagnosis of ASD (n = 151) and in a typically developing comparison group (n = 50), using structured observations and parent reports. Based on the observations, participants' responses to the emotional displays of an interviewer were surprisingly similar. However, compared with parents from the comparison group, parents of a child with ASD reported significantly fewer empathic responses, particularly when the child received a high score on the Autism Diagnostic Observation Schedule. Even though parents report a reduced empathic responsiveness in school-aged children and adolescents with ASD, it may be difficult to find these empathic limitations during brief observations in a structured setting. © 2013 International Society for Autism Research, Wiley Periodicals, Inc.

  11. THE SPECTRUM AND TERM ANALYSIS OF V II

    International Nuclear Information System (INIS)

    Thorne, A. P.; Pickering, J. C.; Semeniuk, J. I.

    2013-01-01

    The spectrum and extended term analysis of V II are presented. Fourier transform spectrometry was used to record high resolution spectra of singly ionized vanadium in the region 1492-5800 Å (67020-17260 cm –1 ) with vanadium-neon and vanadium-argon hollow cathode lamps as sources. The wavenumber uncertainty for the center of gravity of the strongest lines is typically 0.002 cm –1 , an improvement of an order of magnitude over previous measurements. Most of the lines exhibit partly resolved hyperfine structure. The V II energy levels in the 1985 compilation of Sugar and Corliss have been confirmed and revised, with the exception of the high-lying 4f levels and eight of the lower levels. Thirty-nine of the additional eighty-five high levels published by Iglesias et al. have also been confirmed and revised, and three of their missing levels have been found. The energy uncertainty of the revised levels has been reduced by about an order of magnitude. In total, 176 even levels and 233 odd levels are presented. Wavenumbers and classifications are given for 1242 V II lines

  12. Economic Analysis of the Radio Spectrum for Regulatory Purposes

    DEFF Research Database (Denmark)

    Falch, Morten; Tadayoni, Reza

    sector, changed from a matter of pure co-ordination and planning to be an important tool in creation of a competitive environment for various telecommunication services. Regulation of the spectrum has to a certain extend been subject to the same development. Regulation of the spectrum scarcity is however...... the user value as long as there is no market for trade in frequency licenses. The economic value of the radio spectrum has been calculated for six different service applications (fixed links, Maritime and aeronautic applications, broadcasting services, mobile services, private mobile radio network services...

  13. Gamma ray spectrum analysis code: sigmas 1.0

    International Nuclear Information System (INIS)

    Siangsanan, P.; Dharmavanij, W.; Chongkum, S.

    1996-01-01

    We have developed Sigmas 1.0 a software package for data reduction and gamma ray spectra evaluation. It is capable of analysing the gamma-ray spectrum in the range of 0-3 MeV by semiconductor detector, i.e. Ge(Li) or HPGe, peak searching, net area determining, plotting and spectrum displaying. There are two methods for calculating the net area under peaks; the Covell method and non-linear fitting by the method of Levenberg and Marquardt which can fit any multiplet peak in the spectrum. The graphic display was rather fast and user friendly

  14. Converging Pathways in Autism Spectrum Disorders: Interplay Between Synaptic Dysfunction and Immune Responses

    Directory of Open Access Journals (Sweden)

    Irina eVoineagu

    2013-11-01

    Full Text Available Autism spectrum disorders (ASD are highly heritable, yet genetically heterogeneous neurodevelopmental conditions. Recent genome-wide association and gene expression studies have provided evidence supporting the notion that the large number of genetic variants associated with ASD converge toward a core set of dysregulated biological processes. Here we review recent data demonstrating the involvement of synaptic dysfunction and abnormal immune responses in ASD, and discuss the functional interplay between the two phenomena.

  15. Functional Neuroimaging of Sensory Over-Responsivity in Youth With Autism Spectrum Disorders

    OpenAIRE

    Green, Shulamite A.

    2014-01-01

    In addition to the core social and communication symptoms, individuals with autism spectrum disorders (ASD) have high rates of sensory over-responsivity (SOR). Despite the fact that over half of children and adolescents with ASD have SOR, very little is known about the neurobiological bases of this condition. SOR often co-occurs with anxiety disorders, which suggests a possible common biological basis for both SOR and anxiety in a subgroup of youth with ASD. The following studies used functio...

  16. Associations between cytokines, endocrine stress response, and gastrointestinal symptoms in autism spectrum disorder

    OpenAIRE

    Ferguson, Bradley J.; Marler, Sarah; Altstein, Lily L.; Lee, Evon Batey; Mazurek, Micah O.; McLaughlin, Aaron; Macklin, Eric A.; McDonnell, Erin; Davis, Daniel J.; Belenchia, Anthony M.; Gillespie, Catherine H.; Peterson, Catherine A.; Bauman, Margaret L.; Margolis, Kara Gross; Veenstra-VanderWeele, Jeremy

    2016-01-01

    Many children and adolescents with autism spectrum disorder (ASD) have significant gastrointestinal (GI) symptoms, but the etiology is currently unknown. Some individuals with ASD show altered reactivity to stress and altered immune markers relative to typically-developing individuals, particularly stress-responsive cytokines including tumor necrosis factor alpha (TNF-?) and interleukin 6 (IL-6). Acute and chronic stress is associated with the onset and exacerbation of GI symptoms in those wi...

  17. Capacity analysis of spectrum sharing spatial multiplexing MIMO systems

    KAUST Repository

    Yang, Liang; Qaraqe, Khalid A.; Serpedin, Erchin; Alouini, Mohamed-Slim

    2014-01-01

    This paper considers a spectrum sharing (SS) multiple-input multiple-output (MIMO) system operating in a Rayleigh fading environment. First the capacity of a single-user SS spatial multiplexing system is investigated in two scenarios that assume

  18. Meta-Analysis of Parent-Mediated Interventions for Young Children with Autism Spectrum Disorder

    Science.gov (United States)

    Nevill, Rose E.; Lecavalier, Luc; Stratis, Elizabeth A.

    2018-01-01

    A number of studies of parent-mediated interventions in autism spectrum disorder have been published in the last 15 years. We reviewed 19 randomized clinical trials of parent-mediated interventions for children with autism spectrum disorder between the ages of 1 and 6 years and conducted a meta-analysis on their efficacy. Meta-analysis outcomes…

  19. Analytical solution for beam with time-dependent boundary conditions versus response spectrum

    International Nuclear Information System (INIS)

    Gou, P.F.; Panahi, K.K.

    2001-01-01

    This paper studies the responses of a uniform simple beam for which the supports are subjected to time-dependent conditions. Analytical solution in terms of series was presented for two cases: (1) Two supports of a simple beam are subjected to a harmonic motion, and (2) One of the two supports is stationary while the other is subjected to a harmonic motion. The results of the analytical solution were investigated and compared with the results of conventional response spectrum method using the beam finite element model. One of the applications of the results presented in this paper can be used to assess the adequacy and accuracy of the engineering approaches such as response spectra methods. It has been found that, when the excitation frequency equals the fundamental frequency of the beam, the results from response spectrum method are in good agreement with the exact calculation. The effects of initial conditions on the responses are also examined. It seems that the non-zero initial velocity has pronounced effects on the displacement time histories but it has no effect on the maximum accelerations. (author)

  20. SPECTRUM WEIGHTED RESPONSES OF SEVERAL DETECTORS IN MIXED FIELDS OF FAST AND THERMAL NEUTRONS

    Directory of Open Access Journals (Sweden)

    SANG IN KIM

    2014-04-01

    Full Text Available The spectrum weighted responses of various detectors were calculated to provide guidance on the proper selection and use of survey instruments on the basis of their energy response characteristics on the neutron fields. To yield the spectrum weighted response, the detector response functions of 17 neutron-measuring devices were numerically folded with each of the produced calibration neutron spectra through the in-house developed software ‘K-SWR’. The detectors’ response functions were taken from the IAEA Technical Reports Series No. 403 (TRS-403. The reference neutron fields of 21 kinds with 2 spectra groups with different proportions of thermal and fast neutrons have been produced using neutrons from the 241Am-Be sources held in a graphite pile, a bare 241Am-Be source, and a DT neutron generator. Fluence-average energy (Eave varied from 3.8 MeV to 16.9 MeV, and the ambient-dose-equivalent rate [H*(10/h] varied from 0.99 to 16.5 mSv/h.

  1. Response analysis of the dynamic excitation of hen eggs

    OpenAIRE

    Libor Severa

    2007-01-01

    Commercially produced hen eggs have been tested by means of dynamic excitation of the egg-shells with following analysis of their response. The falling steel ball have been chosen as a exciting instrument and the laser vibrometer have been used as a measuring device for the egg response. The reproductibility of the experiments has been relatively high and the surface velocity has been found to be significantly dependent on the position around the meridian. Analysed frequency spectrum has show...

  2. GSAP: FORTRAN code for gamma-spectrum analysis

    International Nuclear Information System (INIS)

    Hnatowicz, V.; Kozma, P.; Ilyushchenko, V.I.

    1989-01-01

    The GSAP program performs fully automatic evaluation of gamma-ray energy spectra measured with semiconductor detectors. After the input data comprising experimental spectrum, energy and FWHM calibrations and parameters controlling the peak search are supplied, the program starts peak searching from the spectrum beginning. The detected peaks are arranged into multiplets which are unfolded by standard non-linear least-squares-fit assuming Gaussian peak and linear background. The program proceeds until all multiplets are processed. The determined peak parameters are printed and the result of each particular fit is shown in the graphical form. 6 refs

  3. Analysis of the laser photoelectron spectrum of CH-2

    International Nuclear Information System (INIS)

    Bunker, P.R.; Sears, T.J.

    1985-01-01

    We have simulated the photoelectron spectrum of CH - 2 using the model described previously [Sears and Bunker, J. Chem. Phys. 79, 5265 (1983)]. The optimization of the fit of the simulated spectrum to the recently observed spectrum of Lineberger and co-workers [J. Chem. Phys. 81, 1048 (1984) and preceding paper] has enabled us to determine the rotation-bending energy levels of triplet CH 2 over an energy range of more than 1 eV. It has also enabled us to determine that the rotational temperature of the CH - 2 in the experiment is 220 K and that, for v 2 = 1, the vibrational temperature is 680 K. For CH - 2 we determine that a/sub e/ = 103 0 and that ν 2 = 1230 cm -1 . The singlet--triplet splitting in methylene is determined to be 3150 +- 30 cm -1 (0.3905 +- 0.004 eV, 9.01 +- 0.09 kcal/mol) from the photoelectron spectrum, in excellent agreement with the more accurate value previously obtained from LMR spectroscopy [McKellar et al., J. Chem. Phys. 79, 5251 (1983)] of 3165 +- 20 cm -1 (0.3924 +- 0.0025 eV, 9.05 +- 0.06 kcal/mol), and the electron affinity of triplet CH 2 is determined to be 0.652 +- 0.006 eV

  4. Analysis of the essential spectrum of singular matrix differential operators

    Czech Academy of Sciences Publication Activity Database

    Ibrogimov, O. O.; Siegl, Petr; Tretter, C.

    2016-01-01

    Roč. 260, č. 4 (2016), s. 3881-3926 ISSN 0022-0396 Institutional support: RVO:61389005 Key words : essential spectrum * system of singular differential equations * operator matrix * Schur complement * magnetohydrodynamics * Stellar equilibrium model Subject RIV: BE - Theoretical Physics Impact factor: 1.988, year: 2016

  5. A Meta-Analysis of the Social Communication Questionnaire: Screening for Autism Spectrum Disorder

    Science.gov (United States)

    Chesnut, Steven R.; Wei, Tianlan; Barnard-Brak, Lucy; Richman, David M.

    2017-01-01

    The current meta-analysis examines the previous research on the utility of the Social Communication Questionnaire as a screening instrument for autism spectrum disorder. Previously published reports have highlighted the inconsistencies between Social Communication Questionnaire-screening results and formal autism spectrum disorder diagnoses. The…

  6. Relative conservatisms of combination methods used in response spectrum analyses of nuclear piping systems

    International Nuclear Information System (INIS)

    Gupta, S.; Kustu, O.; Jhaveri, D.P.; Blume, J.A.

    1983-01-01

    The paper presents the conclusions of a comprehensive study that investigated the relative conservatisms represented by various combination techniques. Two approaches were taken for the study, producing mutually consistent results. In the first, 20 representative nuclear piping systems were systematically analyzed using the response spectrum method. The total response was obtained using nine different combination methods. One procedure, using the SRSS method for combining spatial components of response and the 10% method for combining the responses of different modes (which is currently acceptable to the U.S. NRC), was the standard for comparison. Responses computed by the other methods were normalized to this standard method. These response ratios were then used to develop cumulative frequency-distribution curves, which were used to establish the relative conservatism of the methods in a probabilistic sense. In the second approach, 30 single-degree-of-freedom (SDOF) systems that represent different modes of hypothetical piping systems and have natural frequencies varying from 1 Hz to 30 Hz, were analyzed for 276 sets of three-component recorded ground motion. A set of hypothetical systems assuming a variety of modes and frequency ranges was developed. The responses of these systems were computed from the responses of the SDOF systems by combining the spatial response components by algebraic summation and the individual mode responses by the Navy method, or combining both spatial and modal response components using the SRSS method. Probability density functions and cumulative distribution functions were developed for the ratio of the responses obtained by both methods. (orig./HP)

  7. [Research on the method of copper converting process determination based on emission spectrum analysis].

    Science.gov (United States)

    Li, Xian-xin; Liu, Wen-qing; Zhang, Yu-jun; Si, Fu-qi; Dou, Ke; Wang, Feng-ping; Huang, Shu-hua; Fang, Wu; Wang, Wei-qiang; Huang, Yong-feng

    2012-05-01

    A method of copper converting process determination based on PbO/PbS emission spectrum analysis was described. According to the known emission spectrum of gas molecules, the existence of PbO and PbS was confirmed in the measured spectrum. Through the field experiment it was determined that the main emission spectrum of the slag stage was from PbS, and the main emission spectrum of the copper stage was from PbO. The relative changes in PbO/PbS emission spectrum provide the method of copper converting process determination. Through using the relative intensity in PbO/PbS emission spectrum the copper smelting process can be divided into two different stages, i.e., the slag stage (S phase) and the copper stage (B phase). In a complete copper smelting cycle, a receiving telescope of appropriate view angle aiming at the converter flame, after noise filtering on the PbO/PbS emission spectrum, the process determination agrees with the actual production. Both the theory and experiment prove that the method of copper converting process determination based on emission spectrum analysis is feasible.

  8. A probabilistic capacity spectrum strategy for the reliability analysis of bridge pile shafts considering soil structure interaction

    Directory of Open Access Journals (Sweden)

    Dookie Kim

    Full Text Available This paper presents a probabilistic capacity spectrum strategy for the reliability analysis of a bridge pile shaft, accounting for uncertainties in design factors in the analysis and the soil-structure interaction (SSI. Monte Carlo simulation method (MCS is adopted to determine the probabilities of failure by comparing the responses with defined limit states. The analysis considers the soil structure interaction together with the probabilistic application of the capacity spectrum method for different types of limit states. A cast-in-drilledhole (CIDH extended reinforced concrete pile shaft of a bridge is analysed using the proposed strategy. The results of the analysis show that the SSI can lead to increase or decrease of the structure's probability of failure depending on the definition of the limit states.

  9. On nonstationarity-related errors in modal combination rules of the response spectrum method

    Science.gov (United States)

    Pathak, Shashank; Gupta, Vinay K.

    2017-10-01

    Characterization of seismic hazard via (elastic) design spectra and the estimation of linear peak response of a given structure from this characterization continue to form the basis of earthquake-resistant design philosophy in various codes of practice all over the world. Since the direct use of design spectrum ordinates is a preferred option for the practicing engineers, modal combination rules play central role in the peak response estimation. Most of the available modal combination rules are however based on the assumption that nonstationarity affects the structural response alike at the modal and overall response levels. This study considers those situations where this assumption may cause significant errors in the peak response estimation, and preliminary models are proposed for the estimation of the extents to which nonstationarity affects the modal and total system responses, when the ground acceleration process is assumed to be a stationary process. It is shown through numerical examples in the context of complete-quadratic-combination (CQC) method that the nonstationarity-related errors in the estimation of peak base shear may be significant, when strong-motion duration of the excitation is too small compared to the period of the system and/or the response is distributed comparably in several modes. It is also shown that these errors are reduced marginally with the use of the proposed nonstationarity factor models.

  10. Precise analysis of the three-anyon spectrum

    International Nuclear Information System (INIS)

    Mashkevich, S.V.

    1992-01-01

    We find the exact numbers of ''good'' (found analytically) and ''bad'' states in three-anyon problem. It is shown that the relative number of the ''good'' states tends to one third with energy increasing. We produce an outline of the spectrum which reflects correctly the interpolation between bosonic and fermionic states. We carry out a straightforward calculation of the partition function, which reproduces the known results for the third virial coefficient. 22 refs.; 2 figs.; 7 tab. (author)

  11. Geomechanical time series and its singularity spectrum analysis

    Czech Academy of Sciences Publication Activity Database

    Lyubushin, Alexei A.; Kaláb, Zdeněk; Lednická, Markéta

    2012-01-01

    Roč. 47, č. 1 (2012), s. 69-77 ISSN 1217-8977 R&D Projects: GA ČR GA105/09/0089 Institutional research plan: CEZ:AV0Z30860518 Keywords : geomechanical time series * singularity spectrum * time series segmentation * laser distance meter Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 0.347, year: 2012 http://www.akademiai.com/content/88v4027758382225/fulltext.pdf

  12. Extended analysis of fifth spectrum of bromine: Br V

    International Nuclear Information System (INIS)

    Riyaz, A.; Tauheed, A.; Rahimullah, K.

    2014-01-01

    The fifth spectrum of bromine (Br V) has been studied in the 200–2400 Å wavelength region. The spectrum was photographed on a 3-m normal incidence vacuum spectrograph at the St. Francis Xavier University, Antigonish (Canada) and 6.65-m grazing incidence spectrograph at the Zeeman laboratory (Amsterdam). The light sources used were a triggered spark and sliding spark. The ground configuration of Br V is 4s 2 4p. The excited configurations 4s4p 2 +4s 2 (4d+5d+5s+6s+7s+5g+6g)+4s4p(5p+4f)+4p 2 4d in the even parity system and the 4p 3 +4s 2 (5p+6p+7p+4f)+4s4p4d+4s4p5s configurations in the odd parity system have been studied. Relativistic Hartree–Fock (HFR) and least squares fitted (LSF) parametric calculations have been used to interpret the observed spectrum. 99 levels of Br V have now been established, 43 being new. Among 394 classified spectral lines, 181 are newly classified. The level 4s 2 7s 2 S 1/2 is revised. We estimate the accuracy of our measured wavelengths for sharp and unblended lines to be±0.005 Å. The ionization limit is determined as 479,657±200 cm −1 (59.470±0.025 eV). - Highlights: • The spectrum of Br was recorded on a 3-m spectrograph with triggered spark source. • Atomic transitions for Br V were identified to established new energy levels. • CI calculations with relativistic corrections were made for theoretical predictions. • Weighted oscillator strength (gf) and transition probabilities (gA) were calculated. • Ionization potential of Br V was determined experimentally

  13. A wave parameters and directional spectrum analysis for extreme winds

    OpenAIRE

    Montoya Ramírez, Rubén Darío; Osorio Arias, Andres Fernando; Ortiz Royero, Juan Carlos; Ocampo-Torres, Francisco Javier

    2013-01-01

    In this research a comparison between two of the most popular ocean wave models, WAVEWATCH III™ and SWAN, was performed using data from hurricane Katrina in the Gulf of Mexico. The numerical simulation of sea surface directional wave spectrum and other wave parameters for several parameter- izations and its relation with the drag coefficient was carried out. The simulated data were compared with in-situ NOAA buoy data. For most of the buoys, WAVEWATCH III™ presented the best statistical compar...

  14. Extended analysis of fifth spectrum of bromine: Br V

    Science.gov (United States)

    Riyaz, A.; Tauheed, A.; Rahimullah, K.

    2014-11-01

    The fifth spectrum of bromine (Br V) has been studied in the 200-2400 Å wavelength region. The spectrum was photographed on a 3-m normal incidence vacuum spectrograph at the St. Francis Xavier University, Antigonish (Canada) and 6.65-m grazing incidence spectrograph at the Zeeman laboratory (Amsterdam). The light sources used were a triggered spark and sliding spark. The ground configuration of Br V is 4s24p. The excited configurations 4s4p2+4s2(4d+5d+5s+6s+7s+5g+6g)+4s4p(5p+4f)+4p24d in the even parity system and the 4p3+4s2(5p+6p+7p+4f)+4s4p4d+4s4p5s configurations in the odd parity system have been studied. Relativistic Hartree-Fock (HFR) and least squares fitted (LSF) parametric calculations have been used to interpret the observed spectrum. 99 levels of Br V have now been established, 43 being new. Among 394 classified spectral lines, 181 are newly classified. The level 4s27s 2S1/2 is revised. We estimate the accuracy of our measured wavelengths for sharp and unblended lines to be±0.005 Å. The ionization limit is determined as 479,657±200 cm-1 (59.470±0.025 eV).

  15. WCGM. A gamma-spectrum analysis program rewritten in Windows

    International Nuclear Information System (INIS)

    Szekely, G.

    2009-01-01

    Complete text of publication follows. Introduction The original code was written in Fortran in 1985 and it worked mostly in batch mode. Later the code was redesigned in Pascal and several graphics tools were added. This version (called PGM) is still used, but the limits of MSDOS (memory, graphics, filename length, etc.) make it more and more obsolete. Because of these reasons the redesign of the code is started in order to be able to use it on the most frequently used operating systems, which are nowadays Windows XP and Windows 7. This paper describes the present state of this work and shows some new ways of the usage of the code. In the same time it invites the reader to visit the home page of the code in order to contribute to the further development. Data input Probably one of the main reasons why the original DOS code is still used is that a lot of input formats are accepted. The following short names identify the currently available input spectrum formats: 'ASCII', 'Binary', 'I-format', 'Jyvaeskylae', 'K-format', 'MCA', 'MCAtxt', 'MSI', 'NBI', 'Ortec', 'Oxford/ Nucleus', 'PCA9', 'Tukan'. The most simple ones (ASCII, Binary) contain only the counts of the gamma spectrum, but the more sophisticated ones (I-format, Tukan) also include data for the energy, resolution and efficiency calibrations. The user can choose different levels of interaction during the input process. One can put everything to a control data file and tell the code to use it, or one can manually find the input spectrum and the calibration data during running the code. Spectrum processing After reading the input data the whole spectrum is shown in the main window. To find the peak positions one can use 'Process| Automatic peak search' menu item to scan the displayed interval of the spectrum and assign the peaks with black vertical lines, which were selected by the built-in algorithm. Then the user can fine tune this peak set by manually insert or remove peaks, with the help of the right hand

  16. Emergency Medical Response Capability Analysis

    Science.gov (United States)

    1982-07-01

    Analgesics, non-narcotic Anesthesia aooaratus Antibiotics and anti-bacterials Basin, qash, solution Antidiabetic Agents (Oral) Blade, surgical Knife...for replace- Holder, suture needle nent therapy Inhaler, anesthesia , Yankauer (atner fask) Local anesthetics Intravenous injection sets Lubricant...Medium-Spectrum Erythromycin Kanamycin Clindamycin Narrow-Spectrum Penicillins Oxacillin Methicillin Streptomycin Gentamicin Other Amphotericin B Nystatin

  17. The Real-time Frequency Spectrum Analysis of Neutron Pulse Signal Series

    International Nuclear Information System (INIS)

    Tang Yuelin; Ren Yong; Wei Biao; Feng Peng; Mi Deling; Pan Yingjun; Li Jiansheng; Ye Cenming

    2009-01-01

    The frequency spectrum analysis of neutron pulse signal is a very important method in nuclear stochastic signal processing Focused on the special '0' and '1' of neutron pulse signal series, this paper proposes new rotation-table and realizes a real-time frequency spectrum algorithm under 1G Hz sample rate based on PC with add, address and SSE. The numerical experimental results show that under the count rate of 3X10 6 s -1 , this algorithm is superior to FFTW in time-consumption and can meet the real-time requirement of frequency spectrum analysis. (authors)

  18. NonLTE ANALYSIS OF THE NaI LINES IN THE SOLAR SPECTRUM

    OpenAIRE

    Ivanova, D. V.; Shimansky, V. V.

    2017-01-01

    Solar spectrum of Nal lines by method of the nonLTE analysis is investigated. It shown, that in atmosphere of the Sun the Nal is in moderate ”overrecombination”. The analysis of influence of atomic data, models of atmospheres and damping constants for nonLTE deviation and sodium abundances is made. Observational solar spectrum of strong lines Nal has been synthesized in good approximation. On summary data of 15 lines the sodium abundance is determined:-5.78dex.

  19. Neuroendocrine abnormalities in hypothalamic amenorrhea: spectrum, stability, and response to neurotransmitter modulation.

    Science.gov (United States)

    Perkins, R B; Hall, J E; Martin, K A

    1999-06-01

    To characterize the neuroendocrine patterns of abnormal GnRH secretion in hypothalamic amenorrhea (HA), 49 women with primary and secondary HA underwent frequent sampling of LH in a total of 72 baseline studies over 12-24 h. A subset of women participated in more than one study to address 1) the variability of LH pulse patterns over time; and 2) the impact of modulating opioid, dopaminergic, and adrenergic tone on LH secretory patterns. The frequency and amplitude of LH secretion was compared with that seen in the early follicular phase (EFP) of normally cycling women. The spectrum of abnormalities of LH pulses was 8% apulsatile, 27% low frequency/low amplitude, 8% low amplitude/normal frequency, 43% low frequency/normal amplitude, 14% normal frequency/normal amplitude. Of patients studied overnight, 45% demonstrated a pubertal pattern of augmented LH secretion during sleep. Of patients studied repeatedly, 75% demonstrated at least 2 different patterns of LH secretion, and 33% reverted at least once to a normal pattern of secretion. An increase in LH pulse frequency was seen in 12 of 15 subjects in response to naloxone (opioid receptor antagonist). Clonidine (alpha-2 adrenergic agonist) was associated with a decrease in mean LH in 3 of 3 subjects. An increase in LH pulse frequency was seen in 4 of 8 subjects in response to metoclopramide (dopamine receptor antagonist), but the response was not statistically significant. Baseline abnormalities in LH secretion did not appear to influence response to neurotransmitter modulation. 1) HA represents a spectrum of disordered GnRH secretion that can vary over time; 2) LH pulse patterns at baseline do not appear to influence the ability to respond to neurotransmitter modulation; 3) Opioid and adrenergic tone appear to influence the hypothalamic GnRH pulse generator in some individuals with HA.

  20. Regression of uveal malignant melanomas following cobalt-60 plaque. Correlates between acoustic spectrum analysis and tumor regression

    International Nuclear Information System (INIS)

    Coleman, D.J.; Lizzi, F.L.; Silverman, R.H.; Ellsworth, R.M.; Haik, B.G.; Abramson, D.H.; Smith, M.E.; Rondeau, M.J.

    1985-01-01

    Parameters derived from computer analysis of digital radio-frequency (rf) ultrasound scan data of untreated uveal malignant melanomas were examined for correlations with tumor regression following cobalt-60 plaque. Parameters included tumor height, normalized power spectrum and acoustic tissue type (ATT). Acoustic tissue type was based upon discriminant analysis of tumor power spectra, with spectra of tumors of known pathology serving as a model. Results showed ATT to be correlated with tumor regression during the first 18 months following treatment. Tumors with ATT associated with spindle cell malignant melanoma showed over twice the percentage reduction in height as those with ATT associated with mixed/epithelioid melanomas. Pre-treatment height was only weakly correlated with regression. Additionally, significant spectral changes were observed following treatment. Ultrasonic spectrum analysis thus provides a noninvasive tool for classification, prediction and monitoring of tumor response to cobalt-60 plaque

  1. α spectrum analysis technology research on uranium in environmental water

    International Nuclear Information System (INIS)

    Qiu, Yongmei; Yang, Yong; Ma, Junge

    2009-04-01

    In order to measure the nuclide abundance ratio of uranium in environmental water, the method of '717 anion exchanging resin' is discussed. The dis- traction circuit is determined by 717 anion exchange leaching curve, recovery ratio of anion exchaging, recovery ratio of former disposal and recovery ratio of electrodeposit. The circuit has good result in distracting and enriching uranium by using '717 anion exchanging resin', the resolution of uranium in the spectrum is perfect. The activities and the nuclide abundance ratios of 238 U, 235 U, 234 U in the different reach of some location of INPC have been gained. (authors)

  2. Three Dimensional Response Spectrum Soil Structure Modeling Versus Conceptual Understanding To Illustrate Seismic Response Of Structures

    International Nuclear Information System (INIS)

    Touqan, Abdul Razzaq

    2008-01-01

    Present methods of analysis and mathematical modeling contain so many assumptions that separate them from reality and thus represent a defect in design which makes it difficult to analyze reasons of failure. Three dimensional (3D) modeling is so superior to 1D or 2D modeling, static analysis deviates from the true nature of earthquake load which is ''a dynamic punch'', and conflicting assumptions exist between structural engineers (who assume flexible structures on rigid block foundations) and geotechnical engineers (who assume flexible foundations supporting rigid structures). Thus a 3D dynamic soil-structure interaction is a step that removes many of the assumptions and thus clears reality to a greater extent. However such a model cannot be analytically analyzed. We need to anatomize and analogize it. The paper will represent a conceptual (analogical) 1D model for soil structure interaction and clarifies it by comparing its outcome with 3D dynamic soil-structure finite element analysis of two structures. The aim is to focus on how to calculate the period of the structure and to investigate effect of variation of stiffness on soil-structure interaction

  3. Meta-analysis of Big Five personality traits in autism spectrum disorder.

    Science.gov (United States)

    Lodi-Smith, Jennifer; Rodgers, Jonathan D; Cunningham, Sara A; Lopata, Christopher; Thomeer, Marcus L

    2018-04-01

    The present meta-analysis synthesizes the emerging literature on the relationship of Big Five personality traits to autism spectrum disorder. Studies were included if they (1) either (a) measured autism spectrum disorder characteristics using a metric that yielded a single score quantification of the magnitude of autism spectrum disorder characteristics and/or (b) studied individuals with an autism spectrum disorder diagnosis compared to individuals without an autism spectrum disorder diagnosis and (2) measured Big Five traits in the same sample or samples. Fourteen reviewed studies include both correlational analyses and group comparisons. Eighteen effect sizes per Big Five trait were used to calculate two overall effect sizes per trait. Meta-analytic effects were calculated using random effects models. Twelve effects (per trait) from nine studies reporting correlations yielded a negative association between each Big Five personality trait and autism spectrum disorder characteristics (Fisher's z ranged from -.21 (conscientiousness) to -.50 (extraversion)). Six group contrasts (per trait) from six studies comparing individuals diagnosed with autism spectrum disorder to neurotypical individuals were also substantial (Hedges' g ranged from -.88 (conscientiousness) to -1.42 (extraversion)). The potential impact of personality on important life outcomes and new directions for future research on personality in autism spectrum disorder are discussed in light of results.

  4. Analysis of the sixth spectrum of copper (Cu VI)

    International Nuclear Information System (INIS)

    Raassen, A.J.J.; Kleef, A.M. van

    1981-01-01

    The emission spectrum of copper has been observed in the regions 210-310 Angstroem and 950-1330 Angstroem. In the low-wavelength region 862 lines belonging to transitions between the 3d 5 4p and 3d 6 configurations in Cu VI have been classified while in the upper region 59 lines could be assigned to transitions from 3d 5 4p to 3d 5 4s. Of the 34 levels of the 3d 6 ground configuration 33 have been determined, while 208 of the 214 levels in the 3d 5 4p configuration and 13 of the 74 3d 5 4s levels have been established. For the 3d 6 and 3d 5 4p configurations parametric fits have been performed. The parameter values obtained for these configurations are compared to Hartree-Fock predictions. (orig.)

  5. Analysis of raw AIS spectrum recordings from a LEO satellite

    DEFF Research Database (Denmark)

    Larsen, Jesper Abildgaard; Mortensen, Hans Peter

    2014-01-01

    The AAUSAT3 satellite is a 1U cubesat, which has been developed by students at Aalborg University, Denmark in collaboration with the Danish Maritime Authority. The satellite was launched in February 2013 on a mission to monitor ships from space using their AIS broadcast signals as an indication...... of position. The SDR receiver developed to listen for these AIS signals also allows for sampling and storing of the raw intermediate frequency spectrum, which has been used in order to map channel utilization over the areas of interest for the mission, which is mainly the arctic regions. The SDR based...... receiver used onboard the satellite is using a single chip front-end solution, which down converts the AIS signal located around 162 MHz into an intermediate frequency, with a up to 200 kHz bandwidth. This I/F signal is sampled with a 750 kSPS A/D converter and further processed by an Analog Devices DSP...

  6. Analysis of the sixth spectrum of nickel (Ni VI)

    International Nuclear Information System (INIS)

    Raassen, A.J.J.

    1980-01-01

    The emission spectrum of nickel has been observed in the regions 220-335 Angstroem and 890-1325 Angstroem using a sliding spark light source. In the lower wavelength region 861 lines, belonging to transitions from 3d 4 4p to 3d 5 have been classified, while 403 lines belonging to transitions from 3d 4 4p to 3d 4 4s have been identified in the upper region. All levels of the 3d 5 configuration have been found. Of the 180 levels belonging to 3d 4 4p 179 levels have been determined, while 57 of the 63 levels belonging to 3d 4 4s have been established. Parametric fits to the three configurations are presented and the eigenvector compositions of the levels are reported. The parameter values are compared to Hartree-Fock predictions. (orig.)

  7. Analysis of Transmutation Performance in the Fast Spectrum Systems

    International Nuclear Information System (INIS)

    Zafar, Zafar Iqbal; Kim, Myung Hyun

    2015-01-01

    Nuclear energy, being the most appealing and nonpolluting source has a big issue left i.e. managing the spent nuclear fuel. There are many technological ideas in the design phase or under construction to come up with this limitation. Among the many strategies to incinerate transuranic isotopes (TRU), fission products (FP), and also produce electricity different types of critical and subcritical reactors are proposed. Two most widely studied subcritical reactor options being Accelerator Driven System and a Fusion Fission Hybrid System. In this study, we compare the amount of TRU burnt in different system spectra. To compare the performance, an identical model of a subcritical reactor is used for all the cases, with driving source taken from the potential candidates. A typical fast reactor spectrum is taken as a reference case. It is then compared with an accelerator driven subcritical reactor (ADSR) and a fusion spectrum i.e. 14.1 MeV mono-energetic neutrons. Both later types of driving sources are under extensive investigation but possess totally different pros and cons. Expected price tags for the latter two options are also very different from one another. We take net amount of TRU burnt as the criterion to judge these systems for their performance and worth. Although there is extensive research in progress to design and develop the accelerator or fusion driven systems with many targets in mind. In the current study it is concluded that the notion of TRU burning with accelerator driven systems as the most efficient and the best option to burn TRU has little base when employed in some real system. Presence of coolant and other necessary materials in the core cannot be eliminated

  8. Analysis of Transmutation Performance in the Fast Spectrum Systems

    Energy Technology Data Exchange (ETDEWEB)

    Zafar, Zafar Iqbal; Kim, Myung Hyun [Kyung Hee University, Yongin (Korea, Republic of)

    2015-10-15

    Nuclear energy, being the most appealing and nonpolluting source has a big issue left i.e. managing the spent nuclear fuel. There are many technological ideas in the design phase or under construction to come up with this limitation. Among the many strategies to incinerate transuranic isotopes (TRU), fission products (FP), and also produce electricity different types of critical and subcritical reactors are proposed. Two most widely studied subcritical reactor options being Accelerator Driven System and a Fusion Fission Hybrid System. In this study, we compare the amount of TRU burnt in different system spectra. To compare the performance, an identical model of a subcritical reactor is used for all the cases, with driving source taken from the potential candidates. A typical fast reactor spectrum is taken as a reference case. It is then compared with an accelerator driven subcritical reactor (ADSR) and a fusion spectrum i.e. 14.1 MeV mono-energetic neutrons. Both later types of driving sources are under extensive investigation but possess totally different pros and cons. Expected price tags for the latter two options are also very different from one another. We take net amount of TRU burnt as the criterion to judge these systems for their performance and worth. Although there is extensive research in progress to design and develop the accelerator or fusion driven systems with many targets in mind. In the current study it is concluded that the notion of TRU burning with accelerator driven systems as the most efficient and the best option to burn TRU has little base when employed in some real system. Presence of coolant and other necessary materials in the core cannot be eliminated.

  9. Statistical uncertainty of response characteristic of building-appendage system for spectrum-compatible artificial earthquake motion

    International Nuclear Information System (INIS)

    Kurosaki, A.; Kozeki, M.

    1981-01-01

    Spectrum-compatible artificial time histories of ground motions are frequently used for the seismic design of nuclear power plant structures and components. However, statistical uncertainty of the responses of building structures and mechanical components mounted on the building (building-appendage systems) are anticipated, since an artificial time history is no more than one sample from a population of such time histories that match a specified design response spectrum. This uncertainty may spoil the reliability of the seismic design and therefore the extent of the uncertainty of the response characteristic is a matter of great concern. In this paper, above-mentioned uncertainty of the dynamic response characteristics of the building-appendage system to the spectrum-compatible artificial earthquake is investigated. (orig./RW)

  10. Impaired Overt Facial Mimicry in Response to Dynamic Facial Expressions in High-Functioning Autism Spectrum Disorders

    Science.gov (United States)

    Yoshimura, Sayaka; Sato, Wataru; Uono, Shota; Toichi, Motomi

    2015-01-01

    Previous electromyographic studies have reported that individuals with autism spectrum disorders (ASD) exhibited atypical patterns of facial muscle activity in response to facial expression stimuli. However, whether such activity is expressed in visible facial mimicry remains unknown. To investigate this issue, we videotaped facial responses in…

  11. Electromyographic Responses to Emotional Facial Expressions in 6-7 Year Olds with Autism Spectrum Disorders

    Science.gov (United States)

    Deschamps, P. K. H.; Coppes, L.; Kenemans, J. L.; Schutter, D. J. L. G.; Matthys, W.

    2015-01-01

    This study aimed to examine facial mimicry in 6-7 year old children with autism spectrum disorder (ASD) and to explore whether facial mimicry was related to the severity of impairment in social responsiveness. Facial electromyographic activity in response to angry, fearful, sad and happy facial expressions was recorded in twenty 6-7 year old…

  12. All-sky analysis of the general relativistic galaxy power spectrum

    Science.gov (United States)

    Yoo, Jaiyul; Desjacques, Vincent

    2013-07-01

    We perform an all-sky analysis of the general relativistic galaxy power spectrum using the well-developed spherical Fourier decomposition. Spherical Fourier analysis expresses the observed galaxy fluctuation in terms of the spherical harmonics and spherical Bessel functions that are angular and radial eigenfunctions of the Helmholtz equation, providing a natural orthogonal basis for all-sky analysis of the large-scale mode measurements. Accounting for all the relativistic effects in galaxy clustering, we compute the spherical power spectrum and its covariance matrix and compare it to the standard three-dimensional power spectrum to establish a connection. The spherical power spectrum recovers the three-dimensional power spectrum at each wave number k with its angular dependence μk encoded in angular multipole l, and the contributions of the line-of-sight projection to galaxy clustering such as the gravitational lensing effect can be readily accommodated in the spherical Fourier analysis. A complete list of formulas for computing the relativistic spherical galaxy power spectrum is also presented.

  13. Spectrum analysis with indoor multi-channels gamma-rays spectrometer (NaI(Tl))

    International Nuclear Information System (INIS)

    Hou Shengli; Fan Weihua

    2005-01-01

    Two calculational methods for analyzing the spectrum which measured by indoor low background multi-channels gamma-rays spectrometer (Na(Tl)) to get the specific activity of 226 Ra, 232 Th and 40 K of the sample are discussed, they are the spectrum analysis method and the characteristic energy peak method (inverse matrix method) respectively. The sample spectrum are analyzed with the program designed according to the two methods, and compared with the results by HPGe gamma-rays spectrometer, showing that the relative deviation is ≤10% with the two methods. (authors)

  14. Application of Macro Response Monte Carlo method for electron spectrum simulation

    International Nuclear Information System (INIS)

    Perles, L.A.; Almeida, A. de

    2007-01-01

    During the past years several variance reduction techniques for Monte Carlo electron transport have been developed in order to reduce the electron computation time transport for absorbed dose distribution. We have implemented the Macro Response Monte Carlo (MRMC) method to evaluate the electron spectrum which can be used as a phase space input for others simulation programs. Such technique uses probability distributions for electron histories previously simulated in spheres (called kugels). These probabilities are used to sample the primary electron final state, as well as the creation secondary electrons and photons. We have compared the MRMC electron spectra simulated in homogeneous phantom against the Geant4 spectra. The results showed an agreement better than 6% in the spectra peak energies and that MRMC code is up to 12 time faster than Geant4 simulations

  15. Shock Protection of Portable Electronic Products: Shock Response Spectrum, Damage Boundary Approach, and Beyond

    Directory of Open Access Journals (Sweden)

    Suresh Goyal

    1997-01-01

    Full Text Available The pervasive shock response spectrum (SRS and damage boundary methods for evaluating product fragility and designing external cushioning for shock protection are described in detail with references to the best available literature. Underlying assumptions are carefully reviewed and the central message of the SRS is highlighted, particularly as it relates to standardized drop testing. Shortcomings of these methods are discussed, and the results are extended to apply to more general systems. Finally some general packaging and shock-mounting strategies are discussed in the context of protecting a fragile disk drive in a notebook computer, although the conclusions apply to other products as well. For example, exterior only cushioning (with low restitution to reduce subsequent impacts will provide a slenderer form factor than the next best strategy: interior cushioning with a “dead” hard outer shell.

  16. Investigating the Measurement Properties of the Social Responsiveness Scale in Preschool Children with Autism Spectrum Disorders

    Science.gov (United States)

    Duku, Eric; Vaillancourt, Tracy; Szatmari, Peter; Georgiades, Stelios; Zwaigenbaum, Lonnie; Smith, Isabel M.; Bryson, Susan; Fombonne, Eric; Mirenda, Pat; Roberts, Wendy; Volden, Joanne; Waddell, Charlotte; Thompson, Ann; Bennett, Teresa

    2013-01-01

    The purpose of this study was to examine the measurement properties of the Social Responsiveness Scale in an accelerated longitudinal sample of 4-year-old preschool children with the complementary approaches of categorical confirmatory factor analysis and Rasch analysis. Measurement models based on the literature and other hypothesized measurement…

  17. Preliminary Seismic Response and Fragility Analysis for DACS Cabinet

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Jinho; Kwag, Shinyoung; Lee, Jongmin; Kim, Youngki [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-05-15

    A DACS cabinet is installed in the main control room. The objective of this paper is to perform seismic analyses and evaluate the preliminary structural integrity and seismic capacity of the DACS cabinet. For this purpose, a 3-D finite element model of the DACS cabinet was developed and its modal analyses are carried out to analyze the dynamic characteristics. The response spectrum analyses and the related safety evaluation are then performed for the DACS cabinet subject to seismic loads. Finally, the seismic margin and seismic fragility of the DACS cabinet are investigated. A seismic analysis and preliminary structural integrity of the DACS cabinet under self weight and SSE load have been evaluated. For this purpose, 3-D finite element models of the DACS cabinet were developed. A modal analysis, response spectrum analysis, and seismic fragility analysis were then performed. From the structural analysis results, the DACS cabinet is below the structural design limit of under SSE 0.3g, and can structurally withstand until less than SSE 3g based on an evaluation of the maximum effective stresses. The HCLPF capacity for the DGRS of the SSE 0.3g is 0.55g. A modal analysis, response spectrum analysis, and seismic fragility analysis were then performed. From the structural analysis results, the DACS cabinet is below the structural design limit of under SSE 0.3g, and can structurally withstand until less than SSE 3g based on an evaluation of the maximum effective stresses. The HCLPF capacity for the DGRS of the SSE 0.3g is 0.55g. Therefore, it is concluded that the DACS cabinet was safely designed in that no damage to the preliminary structural integrity and sufficient seismic margin is expected.

  18. Preliminary Seismic Response and Fragility Analysis for DACS Cabinet

    International Nuclear Information System (INIS)

    Oh, Jinho; Kwag, Shinyoung; Lee, Jongmin; Kim, Youngki

    2013-01-01

    A DACS cabinet is installed in the main control room. The objective of this paper is to perform seismic analyses and evaluate the preliminary structural integrity and seismic capacity of the DACS cabinet. For this purpose, a 3-D finite element model of the DACS cabinet was developed and its modal analyses are carried out to analyze the dynamic characteristics. The response spectrum analyses and the related safety evaluation are then performed for the DACS cabinet subject to seismic loads. Finally, the seismic margin and seismic fragility of the DACS cabinet are investigated. A seismic analysis and preliminary structural integrity of the DACS cabinet under self weight and SSE load have been evaluated. For this purpose, 3-D finite element models of the DACS cabinet were developed. A modal analysis, response spectrum analysis, and seismic fragility analysis were then performed. From the structural analysis results, the DACS cabinet is below the structural design limit of under SSE 0.3g, and can structurally withstand until less than SSE 3g based on an evaluation of the maximum effective stresses. The HCLPF capacity for the DGRS of the SSE 0.3g is 0.55g. A modal analysis, response spectrum analysis, and seismic fragility analysis were then performed. From the structural analysis results, the DACS cabinet is below the structural design limit of under SSE 0.3g, and can structurally withstand until less than SSE 3g based on an evaluation of the maximum effective stresses. The HCLPF capacity for the DGRS of the SSE 0.3g is 0.55g. Therefore, it is concluded that the DACS cabinet was safely designed in that no damage to the preliminary structural integrity and sufficient seismic margin is expected

  19. Are there subgroups within the autistic spectrum? A cluster analysis of a group of children with autistic spectrum disorders.

    Science.gov (United States)

    Prior, M; Eisenmajer, R; Leekam, S; Wing, L; Gould, J; Ong, B; Dowe, D

    1998-09-01

    Comprehensive data on the developmental history and current behaviours of a large sample of high-functioning individuals with diagnoses of autism, Asperger's syndrome, or other related disorder were collected via parent interviews. This provided the basis for a taxonomic analysis to search for subgroups. Most participants also completed theory of mind tasks. Three clusters or subgroups were obtained; these differed on theory of mind performance and on verbal abilities. Although subgroups were identified which bore some relationship to clinical differentiation of autistic, Asperger syndrome, and Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) cases, the nature of the differences between them appeared strongly related to ability variables. Examination of the kinds of behaviours that differentiated the groups suggested that a spectrum of autistic disorders on which children differ primarily in term of degrees of social and cognitive impairments could explain the findings.

  20. Response of neural reward regions to food cues in autism spectrum disorders

    Directory of Open Access Journals (Sweden)

    Cascio Carissa J

    2012-05-01

    Full Text Available Abstract Background One hypothesis for the social deficits that characterize autism spectrum disorders (ASD is diminished neural reward response to social interaction and attachment. Prior research using established monetary reward paradigms as a test of non-social reward to compare with social reward may involve confounds in the ability of individuals with ASD to utilize symbolic representation of money and the abstraction required to interpret monetary gains. Thus, a useful addition to our understanding of neural reward circuitry in ASD includes a characterization of the neural response to primary rewards. Method We asked 17 children with ASD and 18 children without ASD to abstain from eating for at least four hours before an MRI scan in which they viewed images of high-calorie foods. We assessed the neural reward network for increases in the blood oxygenation level dependent (BOLD signal in response to the food images Results We found very similar patterns of increased BOLD signal to these images in the two groups; both groups showed increased BOLD signal in the bilateral amygdala, as well as in the nucleus accumbens, orbitofrontal cortex, and insula. Direct group comparisons revealed that the ASD group showed a stronger response to food cues in bilateral insula along the anterior-posterior gradient and in the anterior cingulate cortex than the control group, whereas there were no neural reward regions that showed higher activation for controls than for ASD. Conclusion These results suggest that neural response to primary rewards is not diminished but in fact shows an aberrant enhancement in children with ASD.

  1. The design of video and remote analysis system for gamma spectrum based on LabVIEW

    International Nuclear Information System (INIS)

    Xu Hongkun; Fang Fang; Chen Wei

    2009-01-01

    For the protection of analyst in the measurement,as well as the facilitation of expert to realize the remote analysis, a solution of live video combined with internet access and control is proposed. DirectShow technology and the LabVIEW'S IDT (Internet Develop Toolkit) module are used, video and analysis pages of the gamma energy spectrum are integrated and published in the windows system by IIS (Internet Information Sever). We realize the analysis of gamma spectrum and remote operations by internet. At the same time, the system has a friendly interface and easily to be put into practice. It also has some reference value for the related radioactive measurement. (authors)

  2. Missing and delayed auditory responses in young and older children with autism spectrum disorders

    Directory of Open Access Journals (Sweden)

    J. Christopher eEdgar

    2014-06-01

    Full Text Available Background: The development of left and right superior temporal gyrus (STG 50ms (M50 and 100ms (M100 auditory responses in typically developing children (TD and in children with autism spectrum disorder (ASD was examined. It was hypothesized that (1 M50 responses would be observed equally often in younger and older children, (2 M100 responses would be observed more often in older than younger children indicating later development of secondary auditory areas, and (3 M100 but not M50 would be observed less often in ASD than TD in both age groups, reflecting slower maturation of later developing auditory areas in ASD. Methods: 35 typically developing controls, 63 ASD without language impairment (ASD-LI, and 38 ASD with language impairment (ASD+LI were recruited.The presence or absence of a STG M50 and M100 was scored. Subjects were grouped into younger (6 to 10-years-old and older groups (11 to 15-years-old. Results: Although M50 responses were observed equally often in older and younger subjects and equally often in TD and ASD, left and right M50 responses were delayed in ASD-LI and ASD+LI. Group comparisons showed that in younger subjects M100 responses were observed more often in TD than ASD+LI (90% vs 66%, p=0.04, with no differences between TD and ASD-LI (90% vs 76% p=0.14 or between ASD-LI and ASD+LI (76% vs 66%, p=0.53. In older subjects, whereas no differences were observed between TD and ASD+LI, responses were observed more often in ASD-LI than ASD+LI. Conclusions: Although present in all groups, M50 responses were delayed in ASD, suggesting delayed development of earlier developing auditory areas. Examining the TD data, findings indicated that by 11 years a right M100 should be observed in 100% of subjects and a left M100 in 80% of subjects. Thus, by 11years, lack of a left and especially right M100 offers neurobiological insight into sensory processing that may underlie language or cognitive impairment.

  3. Mitochondrial disease in autism spectrum disorder patients: a cohort analysis.

    Science.gov (United States)

    Weissman, Jacqueline R; Kelley, Richard I; Bauman, Margaret L; Cohen, Bruce H; Murray, Katherine F; Mitchell, Rebecca L; Kern, Rebecca L; Natowicz, Marvin R

    2008-01-01

    Previous reports indicate an association between autism spectrum disorders (ASD) and disorders of mitochondrial oxidative phosphorylation. One study suggested that children with both diagnoses are clinically indistinguishable from children with idiopathic autism. There are, however, no detailed analyses of the clinical and laboratory findings in a large cohort of these children. Therefore, we undertook a comprehensive review of patients with ASD and a mitochondrial disorder. We reviewed medical records of 25 patients with a primary diagnosis of ASD by DSM-IV-TR criteria, later determined to have enzyme- or mutation-defined mitochondrial electron transport chain (ETC) dysfunction. Twenty-four of 25 patients had one or more major clinical abnormalities uncommon in idiopathic autism. Twenty-one patients had histories of significant non-neurological medical problems. Nineteen patients exhibited constitutional symptoms, especially excessive fatigability. Fifteen patients had abnormal neurological findings. Unusual developmental phenotypes included marked delay in early gross motor milestones (32%) and unusual patterns of regression (40%). Levels of blood lactate, plasma alanine, and serum ALT and/or AST were increased at least once in 76%, 36%, and 52% of patients, respectively. The most common ETC disorders were deficiencies of complex I (64%) and complex III (20%). Two patients had rare mtDNA mutations of likely pathogenicity. Although all patients' initial diagnosis was idiopathic autism, careful clinical and biochemical assessment identified clinical findings that differentiated them from children with idiopathic autism. These and prior data suggest a disturbance of mitochondrial energy production as an underlying pathophysiological mechanism in a subset of individuals with autism.

  4. Mitochondrial disease in autism spectrum disorder patients: a cohort analysis.

    Directory of Open Access Journals (Sweden)

    Jacqueline R Weissman

    Full Text Available Previous reports indicate an association between autism spectrum disorders (ASD and disorders of mitochondrial oxidative phosphorylation. One study suggested that children with both diagnoses are clinically indistinguishable from children with idiopathic autism. There are, however, no detailed analyses of the clinical and laboratory findings in a large cohort of these children. Therefore, we undertook a comprehensive review of patients with ASD and a mitochondrial disorder.We reviewed medical records of 25 patients with a primary diagnosis of ASD by DSM-IV-TR criteria, later determined to have enzyme- or mutation-defined mitochondrial electron transport chain (ETC dysfunction. Twenty-four of 25 patients had one or more major clinical abnormalities uncommon in idiopathic autism. Twenty-one patients had histories of significant non-neurological medical problems. Nineteen patients exhibited constitutional symptoms, especially excessive fatigability. Fifteen patients had abnormal neurological findings. Unusual developmental phenotypes included marked delay in early gross motor milestones (32% and unusual patterns of regression (40%. Levels of blood lactate, plasma alanine, and serum ALT and/or AST were increased at least once in 76%, 36%, and 52% of patients, respectively. The most common ETC disorders were deficiencies of complex I (64% and complex III (20%. Two patients had rare mtDNA mutations of likely pathogenicity.Although all patients' initial diagnosis was idiopathic autism, careful clinical and biochemical assessment identified clinical findings that differentiated them from children with idiopathic autism. These and prior data suggest a disturbance of mitochondrial energy production as an underlying pathophysiological mechanism in a subset of individuals with autism.

  5. Vibrational analysis of Fourier transform spectrum of the B u )–X g ...

    Indian Academy of Sciences (India)

    improved by putting the wave number of band origins in Deslandre table. The vibrational analysis was supported by determining the Franck–Condon factor and r-centroid values. Keywords. Fourier transform spectroscopy; electronic spectrum of selenium dimer; vibrational analysis; Franck–Condon factor; r-centroid values.

  6. Sociosexuality Education for Persons with Autism Spectrum Disorders Using Principles of Applied Behavior Analysis

    Science.gov (United States)

    Wolfe, Pamela S.; Condo, Bethany; Hardaway, Emily

    2009-01-01

    Applied behavior analysis (ABA) has emerged as one of the most effective empirically based strategies for instructing individuals with autism spectrum disorders (ASD). Four ABA-based strategies that have been found effective are video modeling, visual strategies, social script fading, and task analysis. Individuals with ASD often struggle with…

  7. Joint attention responses of children with autism spectrum disorder to simple versus complex music.

    Science.gov (United States)

    Kalas, Amy

    2012-01-01

    Joint attention deficits are viewed as one of the earliest manifestations and most characteristic features of the social deficits in Autism Spectrum Disorder (ASD). The purpose of this study was to examine the effect of simple versus complex music on joint attention of children with ASD. Thirty children with a diagnosis of ASD participated in this study. Fifteen of the participants were diagnosed with severe ASD and 15 were diagnosed with mild/moderate ASD. Each participant took part in six, 10-minute individual music conditions (3 simple & 3 complex) over a 3-week period. Each condition was designed to elicit responses to joint attention. RESULTS indicated a statistically significant interaction between music modality and functioning level. Therefore, the effect of simple versus complex music was dependent on functioning level. Specifically, the Simple Music Condition was more effective in eliciting Responses to Joint Attention (RJA) for children diagnosed with severe ASD, whereas the Complex Music Condition was more effective in eliciting RJA for children diagnosed with mild/moderate ASD. The results of the present study indicate that for children in the severe range of functioning, music that is simple, with clear and predictable pattems, may be most effective in eliciting responses to bids for joint attention. On the contrary, for children in the mild/moderate range of functioning, music that is more complex and variable may be most effective in eliciting responses to bids for joint attention. These results demonstrate that careful manipulation of specific musical elements can help provide the optimal conditions for facilitating joint attention with children with ASD.

  8. Investigating the autonomic nervous system response to anxiety in children with autism spectrum disorders.

    Science.gov (United States)

    Kushki, Azadeh; Drumm, Ellen; Pla Mobarak, Michele; Tanel, Nadia; Dupuis, Annie; Chau, Tom; Anagnostou, Evdokia

    2013-01-01

    Assessment of anxiety symptoms in autism spectrum disorders (ASD) is a challenging task due to the symptom overlap between the two conditions as well as the difficulties in communication and awareness of emotions in ASD. This motivates the development of a physiological marker of anxiety in ASD that is independent of language and does not require observation of overt behaviour. In this study, we investigated the feasibility of using indicators of autonomic nervous system (ANS) activity for this purpose. Specially, the objectives of the study were to 1) examine whether or not anxiety causes significant measurable changes in indicators of ANS in an ASD population, and 2) characterize the pattern of these changes in ASD. We measured three physiological indicators of the autonomic nervous system response (heart rate, electrodermal activity, and skin temperature) during a baseline (movie watching) and anxiety condition (Stroop task) in a sample of typically developing children (n = 17) and children with ASD (n = 12). The anxiety condition caused significant changes in heart rate and electrodermal activity in both groups, however, a differential pattern of response was found between the two groups. In particular, the ASD group showed elevated heart rate during both baseline and anxiety conditions. Elevated and blunted phasic electrodermal activity were found in the ASD group during baseline and anxiety conditions, respectively. Finally, the ASD group did not show the typical decrease in skin temperature in response to anxiety. These results suggest that 1) signals of the autonomic nervous system may be used as indicators of anxiety in children with ASD, and 2) ASD may be associated with an atypical autonomic response to anxiety that is most consistent with sympathetic over-arousal and parasympathetic under-arousal.

  9. On Transform Domain Communication Systems under Spectrum Sensing Mismatch: A Deterministic Analysis.

    Science.gov (United States)

    Jin, Chuanxue; Hu, Su; Huang, Yixuan; Luo, Qu; Huang, Dan; Li, Yi; Gao, Yuan; Cheng, Shaochi

    2017-07-08

    Towards the era of mobile Internet and the Internet of Things (IoT), numerous sensors and devices are being introduced and interconnected. To support such an amount of data traffic, traditional wireless communication technologies are facing challenges both in terms of the increasing shortage of spectrum resources and massive multiple access. The transform-domain communication system (TDCS) is considered as an alternative multiple access system, where 5G and mobile IoT are mainly focused. However, previous studies about TDCS are under the assumption that the transceiver has the global spectrum information, without the consideration of spectrum sensing mismatch (SSM). In this paper, we present the deterministic analysis of TDCS systems under arbitrary given spectrum sensing scenarios, especially the influence of the SSM pattern to the signal to noise ratio (SNR) performance. Simulation results show that arbitrary SSM pattern can lead to inferior bit error rate (BER) performance.

  10. [Quantitative spectrum analysis of characteristic gases of spontaneous combustion coal].

    Science.gov (United States)

    Liang, Yun-Tao; Tang, Xiao-Jun; Luo, Hai-Zhu; Sun, Yong

    2011-09-01

    Aimed at the characteristics of spontaneous combustion gas such as a variety of gases, lou limit of detection, and critical requirement of safety, Fourier transform infrared (FTIR) spectral analysis is presented to analyze characteristic gases of spontaneous combustion In this paper, analysis method is introduced at first by combing characteristics of absorption spectra of analyte and analysis requirement. Parameter setting method, sample preparation, feature variable abstract and analysis model building are taken into consideration. The methods of sample preparation, feature abstraction and analysis model are introduced in detail. And then, eleven kinds of gases were tested with Tensor 27 spectrometer. CH4, C2H6, C3H8, iC4H10, nC4H10, C2 H4, C3 H6, C3 H2, SF6, CO and CO2 were included. The optical path length was 10 cm while the spectra resolution was set as 1 cm(-1). The testing results show that the detection limit of all analytes is less than 2 x 10(-6). All the detection limits fit the measurement requirement of spontaneous combustion gas, which means that FTIR may be an ideal instrument and the analysis method used in this paper is competent for spontaneous combustion gas measurement on line.

  11. Hoarding in Youth with Autism Spectrum Disorders and Anxiety: Incidence, Clinical Correlates, and Behavioral Treatment Response.

    Science.gov (United States)

    Storch, Eric A; Nadeau, Joshua M; Johnco, Carly; Timpano, Kiara; McBride, Nicole; Jane Mutch, P; Lewin, Adam B; Murphy, Tanya K

    2016-05-01

    This study examined the nature and correlates of hoarding among youth with autism spectrum disorders (ASD). Forty children with ASD and a comorbid anxiety disorder were administered a battery of clinician-administered measures assessing presence of psychiatric disorders and anxiety severity. Parents completed questionnaires related to child hoarding behaviors, social responsiveness, internalizing and externalizing behaviors, and functional impairment. We examined the impact of hoarding behaviors on treatment response in a subsample of twenty-six youth who completed a course of personalized cognitive-behavioral therapy targeting anxiety symptoms. Hoarding symptoms were common and occurred in a clinically significant manner in approximately 25 % of cases. Overall hoarding severity was associated with increased internalizing and anxiety/depressive symptoms, externalizing behavior, and attention problems. Discarding items was associated with internalizing and anxious/depressive symptoms, but acquisition was not. Hoarding decreased following cognitive-behavioral therapy but did not differ between treatment responders and non-responders. These data are among the first to examine hoarding among youth with ASD; implications of study findings and future directions are highlighted.

  12. Galaxy power-spectrum responses and redshift-space super-sample effect

    Science.gov (United States)

    Li, Yin; Schmittfull, Marcel; Seljak, Uroš

    2018-02-01

    As a major source of cosmological information, galaxy clustering is susceptible to long-wavelength density and tidal fluctuations. These long modes modulate the growth and expansion rate of local structures, shifting them in both amplitude and scale. These effects are often named the growth and dilation effects, respectively. In particular the dilation shifts the baryon acoustic oscillation (BAO) peak and breaks the assumption of the Alcock-Paczynski (AP) test. This cannot be removed with reconstruction techniques because the effect originates from long modes outside the survey. In redshift space, the long modes generate a large-scale radial peculiar velocity that affects the redshift-space distortion (RSD) signal. We compute the redshift-space response functions of the galaxy power spectrum to long density and tidal modes at leading order in perturbation theory, including both the growth and dilation terms. We validate these response functions against measurements from simulated galaxy mock catalogs. As one application, long density and tidal modes beyond the scale of a survey correlate various observables leading to an excess error known as the super-sample covariance, and thus weaken their constraining power. We quantify the super-sample effect on BAO, AP, and RSD measurements, and study its impact on current and future surveys.

  13. A Meta-Analysis of Sensory Modulation Symptoms in Individuals with Autism Spectrum Disorders

    Science.gov (United States)

    Ben-Sasson, Ayelet; Hen, Liat; Fluss, Ronen; Cermak, Sharon A.; Engel-Yeger, Batya; Gal, Eynat

    2009-01-01

    Sensory modulation symptoms are common in persons with autism spectrum disorders (ASD); however have a heterogeneous presentation. Results from 14 studies indicated a significant high difference between ASD and typical groups in the presence/frequency of sensory symptoms, with the greatest difference in under-responsivity, followed by…

  14. Spectral analysis of the fifth spectrum of indium: In V

    International Nuclear Information System (INIS)

    Swapnil; Tauheed, A.

    2016-01-01

    The fifth spectrum of indium (In V) has been investigated in the grazing and normal incidence wavelength regions. In"4"+ is a Rh-like ion with the ground configuration 4p"64d"9 and first excited configurations of the type 4p"64d"8nℓ (n≥4). The theoretical predications for this ion were made by Cowan's quasi-relativistic Hartree–Fock code with superposition of configurations involving 4p"64d"8(5p+6p+7p+4f+5f+6f), 4p"54d"1"0, 4p"64d"75s(5p+4f) for the odd parity matrix and 4p"64d"8 (5s+6s+7s+5d+6d), 4p"64d"7(5s"2+5p"2) for the even parity system. The spectra used for this work were recorded on 10.7 m grazing and normal incidence spectrographs at the National Institute of Standards and Technology, Gaithersburg, Maryland (USA) and also on a 3-m normal incidence vacuum spectrograph at Antigonish (Canada). The sources used were a sliding spark and a triggered spark respectively. Two hundred and thirty two energy levels based on the identification of 873 spectral lines have been established, forty six being new. Least squares fitted parametric calculations were used to interpret the observed level structure. The energy levels were optimized using a level optimization computer program (LOPT). Our wavelength accuracy for sharp and unblended lines is estimated to be within ±0.005 Å for λ below 400 Å and ±0.006 Å up to 1200 Å. - Highlights: • Indium spectra were recorded on both grazing and normal incidence spectrographs. • Calculations were made with Cowan's quasi-relativistic Hartree–Fock code. • New atomic transitions of In V were identified with newly found energy levels. • Uncertainties and Ritz wavelengths of all observed transitions were calculated. • Weighted transition probabilities (gA) were calculated.

  15. EPR spectrum deconvolution and dose assessment of fossil tooth enamel using maximum likelihood common factor analysis

    International Nuclear Information System (INIS)

    Vanhaelewyn, G.; Callens, F.; Gruen, R.

    2000-01-01

    In order to determine the components which give rise to the EPR spectrum around g = 2 we have applied Maximum Likelihood Common Factor Analysis (MLCFA) on the EPR spectra of enamel sample 1126 which has previously been analysed by continuous wave and pulsed EPR as well as EPR microscopy. MLCFA yielded agreeing results on three sets of X-band spectra and the following components were identified: an orthorhombic component attributed to CO - 2 , an axial component CO 3- 3 , as well as four isotropic components, three of which could be attributed to SO - 2 , a tumbling CO - 2 and a central line of a dimethyl radical. The X-band results were confirmed by analysis of Q-band spectra where three additional isotropic lines were found, however, these three components could not be attributed to known radicals. The orthorhombic component was used to establish dose response curves for the assessment of the past radiation dose, D E . The results appear to be more reliable than those based on conventional peak-to-peak EPR intensity measurements or simple Gaussian deconvolution methods

  16. Spectrum-Based and Collaborative Network Topology Analysis and Visualization

    Science.gov (United States)

    Hu, Xianlin

    2013-01-01

    Networks are of significant importance in many application domains, such as World Wide Web and social networks, which often embed rich topological information. Since network topology captures the organization of network nodes and links, studying network topology is very important to network analysis. In this dissertation, we study networks by…

  17. QUASAR - an interactive program for spectrum analysis in personal computers

    International Nuclear Information System (INIS)

    Auler, L.T.; Nobrega, J.A.W. da.

    1991-11-01

    The QUASAR software for the interactive analysis and report of energy (pulse-height) and time (multichannel scaling) spectra is described. The operating instructions as well as the mathematical methods and algorithms used by the program are presented in detail. This program is an extension to the PULSAR program. (author)

  18. Spectrum analysis of a voltage source converter due to semiconductor voltage drops

    DEFF Research Database (Denmark)

    Rasmussen, Tonny Wederberg; Eltouki, Mustafa

    2017-01-01

    It is known that power electronic voltage source converters are non-ideal. This paper presents a state-of-the-art review on the effect of semiconductor voltage drop on the output voltage spectrum, using single-phase H-bridge two-level converter topology with natural sampled pulse width modulation....... The paper describes the analysis of output voltage spectrum, when the semiconductor voltage drop is added. The results of the analysis of the spectral contribution including and excluding semiconductor voltage drop reveal a good agreement between the theoretical results, simulations and laboratory...

  19. Prevalence of Schizophrenia Spectrum Disorders in Average-IQ Adults with Autism Spectrum Disorders: A Meta-Analysis

    Science.gov (United States)

    Lugo Marín, Jorge; Rodríguez-Franco, Montserrat Alviani; Mahtani Chugani, Vinita; Magán Maganto, María; Díez Villoria, Emiliano; Canal Bedia, Ricardo

    2018-01-01

    Since their separation as independent diagnostics, autism spectrum disorders (ASD) and schizophrenia spectrum disorders (SSD) have been conceptualized as mutually exclusive disorders. Similarities between both disorders can lead to misdiagnosis, especially when it comes to average-IQ adults who were not identified during childhood. The aim of this…

  20. [Signal analysis and spectrum distortion correction for tunable diode laser absorption spectroscopy system].

    Science.gov (United States)

    Bao, Wei-Yi; Zhu, Yong; Chen, Jun; Chen, Jun-Qing; Liang, Bo

    2011-04-01

    In the present paper, the signal of a tunable diode laser absorption spectroscopy (TDLAS) trace gas sensing system, which has a wavelength modulation with a wide range of modulation amplitudes, is studied based on Fourier analysis method. Theory explanation of spectrum distortion induced by laser intensity amplitude modulation is given. In order to rectify the spectrum distortion, a method of synchronous amplitude modulation suppression by a variable optical attenuator is proposed. To validate the method, an experimental setup is designed. Absorption spectrum measurement experiments on CO2 gas were carried out. The results show that the residual laser intensity modulation amplitude of the experimental system is reduced to -0.1% of its original value and the spectrum distortion improvement is 92% with the synchronous amplitude modulation suppression. The modulation amplitude of laser intensity can be effectively reduced and the spectrum distortion can be well corrected by using the given correction method and system. By using a variable optical attenuator in the TDLAS (tunable diode laser absorption spectroscopy) system, the dynamic range requirements of photoelectric detector, digital to analog converter, filters and other aspects of the TDLAS system are reduced. This spectrum distortion correction method can be used for online trace gas analyzing in process industry.

  1. A meta-analysis of the social communication questionnaire: Screening for autism spectrum disorder.

    Science.gov (United States)

    Chesnut, Steven R; Wei, Tianlan; Barnard-Brak, Lucy; Richman, David M

    2017-11-01

    The current meta-analysis examines the previous research on the utility of the Social Communication Questionnaire as a screening instrument for autism spectrum disorder. Previously published reports have highlighted the inconsistencies between Social Communication Questionnaire-screening results and formal autism spectrum disorder diagnoses. The variations in accuracy resulted in some researchers questioning the validity of the Social Communication Questionnaire. This study systematically examined the accuracy of the Social Communication Questionnaire as a function of the methodological decisions made by researchers screening for autism spectrum disorder over the last 15 years. Findings from this study suggest that the Social Communication Questionnaire is an acceptable screening instrument for autism spectrum disorder (area under the curve = 0.885). Variations in methodological decisions, however, greatly influenced the accuracy of the Social Communication Questionnaire in screening for autism spectrum disorder. Of these methodological variations, using the Current instead of the Lifetime version of the Social Communication Questionnaire resulted in the largest detrimental effect ( d = -3.898), followed by using the Social Communication Questionnaire with individuals younger than 4 years of age ( d = -2.924) and relying upon convenience samples ( d = -4.828 for clinical samples, -2.734 for convenience samples, and -1.422 for community samples). Directions for future research and implications for using the Social Communication Questionnaire to screen for autism spectrum disorder are discussed.

  2. [Air Dielectric Barrier Discharge Emission Spectrum Measurement and Particle Analysis of Discharge Process].

    Science.gov (United States)

    Shen, Shuang-yan; Jin, Xing; Zhang, Peng

    2016-02-01

    The emission spectrum detection and diagnosis is one of the most common methods of application to the plasma. It provides wealth of information of the chemical and physical process of the plasma. The analysis of discharge plasma dynamic behavior plays an important role in the study of gas discharge mechanism and application. An air dielectric discharge spectrum measuring device was designed and the emission spectrum data was measured under the experimental condition. The plasma particles evolution was analyzed from the emission spectrum. The numerical calculation model was established and the density equation, energy transfer equation and the Boltzmann equation was coupled to analyze the change of the particle density to explain the emission spectrum characteristics. The results are that the particle density is growing with the increasing of reduced electric field. The particle density is one or two orders of magnitude difference for the same particle at the same moment for the reduced electric field of 40, 60 or 80 Td. A lot of N₂ (A³), N₂ (A³) and N₂ (C³) particles are generated by the electric field excitation. However, it transforms quickly due to the higher energy level. The transformation returns to the balance after the discharge of 10⁻⁶ s. The emission spectrometer measured in the experiments is mostly generated by the transition of excited nitrogen. The peak concentration of O₂ (A¹), O₂ (B¹) and O₂ (A³ ∑⁺u) is not low compared to the excited nitrogen molecules. These particles energy is relatively low and the transition spectral is longer. The spectrometer does not capture the oxygen emission spectrum. And the peak concentration of O particles is small, so the transition emission spectrum is weak. The calculation results of the stabled model can well explain the emission spectrum data.

  3. Quantitative analysis of overlapping XPS peaks by spectrum reconstruction

    DEFF Research Database (Denmark)

    Graat, Peter C.J.; Somers, Marcel A. J.

    1998-01-01

    parameters. The values obtained for the oxide film thickness were compared with thickness values determined from the intensity of the corresponding O 1s spectra and with thickness values resulting from ellipsometric analysis. The sensitivity of the reconstruction procedure with regard to film thickness...... contributions in the spectra owing to inelastic scattering of signal electrons were calculated from the depth distributions of these constituents and their reference spectra. In the reconstruction procedure the film thickness and the concentrations of Fe/sup 2+/ and Fe/sup 3+/ in the oxide film were used as fit...

  4. Early Sensory Over-Responsivity in Toddlers with Autism Spectrum Disorders as a Predictor of Family Impairment and Parenting Stress

    Science.gov (United States)

    Ben-Sasson, A.; Soto, T. W.; Martinez-Pedraza, F.; Carter, A. S.

    2013-01-01

    Background: Sensory over-responsivity (SOR) affects many individuals with autism spectrum disorders (ASD), often leading to stressful encounters during daily routines. Methods: This study describes the associations between early SOR symptoms and the longitudinal course of restrictions in family life activities and parenting stress across three…

  5. Associations between Language Development and Skin Conductance Responses to Faces and Eye Gaze in Children with Autism Spectrum Disorder

    Science.gov (United States)

    Stagg, Steven D.; Davis, Robert; Heaton, Pamela

    2013-01-01

    Attention to social stimuli is associated with language development, and arousal is associated with the increased viewing of stimuli. We investigated whether skin conductance responses (SCRs) are associated with language development in autism spectrum disorder (ASD): a population that shows abnormalities in both attention to others and language…

  6. Effects of a Multimedia Social Skills Program in Increasing Social Responses and Initiations of Children with Autism Spectrum Disorder

    Science.gov (United States)

    Block, Heidi M.; Radley, Keith C.; Jenson, William R.; Clark, Elaine; O'Neill, Robert E.

    2015-01-01

    The current study evaluated the effectiveness of Superheroes Social Skills, a multimedia social skills package, in improving social responsiveness and social initiation behaviors of four elementary school children with an autism spectrum disorder (ASD). The program was implemented in a public school setting in the southwestern United States for…

  7. Heart Rate Profiles of Children with and without Autism Spectrum Disorder in Response to Physical Play: A Preliminary Investigation

    Science.gov (United States)

    Breslin, Casey M.; Rudisill, Mary E.; Wadsworth, Danielle W.

    2015-01-01

    In this study, the heart rate response of children with and without autism spectrum disorder (ASD) exposed to outdoor free play sessions during preschool was examined. Participants (n = 7; four children with ASD and three children who show typical development) wore Actiheart heart rate monitors during 6 school days. Using a single-subject design,…

  8. Prediction of physicochemical properties of FCC feedstock by Chemometric analysis of their ultraviolet spectrum

    International Nuclear Information System (INIS)

    Baldrich Ferrer, Carlos A

    2008-01-01

    Chemometric analysis by Partial Least Squares (PLS) has been applied in this work to correlate the ultraviolet spectrum of combined Fluid Catalytic Cracking (FCC) feedstock with their physicochemical properties. The prediction errors obtained in the validation process using refinery samples demonstrate the accuracy of the predicted properties. This new analytical methodology allows obtaining in one analysis detailed information about the most important physicochemical properties of FCC feedstock and could be used as a valuable tool for operational analysis

  9. The FTS atomic spectrum tool (FAST) for rapid analysis of line spectra

    Science.gov (United States)

    Ruffoni, M. P.

    2013-07-01

    The FTS Atomic Spectrum Tool (FAST) is an interactive graphical program designed to simplify the analysis of atomic emission line spectra obtained from Fourier transform spectrometers. Calculated, predicted and/or known experimental line parameters are loaded alongside experimentally observed spectral line profiles for easy comparison between new experimental data and existing results. Many such line profiles, which could span numerous spectra, may be viewed simultaneously to help the user detect problems from line blending or self-absorption. Once the user has determined that their experimental line profile fits are good, a key feature of FAST is the ability to calculate atomic branching fractions, transition probabilities, and oscillator strengths-and their uncertainties-which is not provided by existing analysis packages. Program SummaryProgram title: FAST: The FTS Atomic Spectrum Tool Catalogue identifier: AEOW_v1_0 Program summary URL: http://cpc.cs.qub.ac.uk/summaries/AEOW_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU General Public License version 3 No. of lines in distributed program, including test data, etc.: 293058 No. of bytes in distributed program, including test data, etc.: 13809509 Distribution format: tar.gz Programming language: C++. Computer: Intel x86-based systems. Operating system: Linux/Unix/Windows. RAM: 8 MB minimum. About 50-200 MB for a typical analysis. Classification: 2.2, 2.3, 21.2. Nature of problem: Visualisation of atomic line spectra including the comparison of theoretical line parameters with experimental atomic line profiles. Accurate intensity calibration of experimental spectra, and the determination of observed relative line intensities that are needed for calculating atomic branching fractions and oscillator strengths. Solution method: FAST is centred around a graphical interface, where a user may view sets of experimental line profiles and compare

  10. Sustainability as Social Contract: Textile and Apparel Professionals’ Value Conflicts within the Corporate Moral Responsibility Spectrum

    Directory of Open Access Journals (Sweden)

    Rachel LoMonaco-Benzing

    2016-12-01

    Full Text Available Current discussions of sustainability in the textile and apparel (T&A supply chain tend to focus on consumer behavior or methods of production. Few studies investigate how T&A supply chain members experience corporate sustainability initiatives within their own moral value spectrum. This study was designed to describe the gaps that might exist between personal and corporate moral values of T&A supply chain members, and how individuals manage such gaps to align personal and corporate identities. The researchers investigated the views of ten T&A supply chain members residing in the United States, both as employees and consumers of T&A companies, through semi-structured interviews. Dunfee’s extant social contracts and Schwartz’s theory of basic values were used as theoretical frameworks to better understand the participants’ lived experiences in negotiating personal and corporate expectations. The findings revealed three themes: (a nature of the value gap; (b frustration due to the value gap; and (c strategies to manage the value gap. The strategies used to realign values split into either those that held sustainability as their responsibility and worked to move corporate values toward their personal values; or those that shifted the blame to others so that their values could remain untouched.

  11. Children on the autism spectrum update their behaviour in response to a volatile environment.

    Science.gov (United States)

    Manning, Catherine; Kilner, James; Neil, Louise; Karaminis, Themelis; Pellicano, Elizabeth

    2017-09-01

    Typical adults can track reward probabilities across trials to estimate the volatility of the environment and use this information to modify their learning rate (Behrens et al., 2007). In a stable environment, it is advantageous to take account of outcomes over many trials, whereas in a volatile environment, recent experience should be more strongly weighted than distant experience. Recent predictive coding accounts of autism propose that autistic individuals will demonstrate atypical updating of their behaviour in response to the statistics of the reward environment. To rigorously test this hypothesis, we administered a developmentally appropriate version of Behrens et al.'s (2007) task to 34 cognitively able children on the autism spectrum aged between 6 and 14 years, 32 age- and ability-matched typically developing children and 19 typical adults. Participants were required to choose between a green and a blue pirate chest, each associated with a randomly determined reward value between 0 and 100 points, with a combined total of 100 points. On each trial, the reward was given for one stimulus only. In the stable condition, the ratio of the blue or green response being rewarded was fixed at 75:25. In the volatile condition, the ratio alternated between 80:20 and 20:80 every 20 trials. We estimated the learning rate for each participant by fitting a delta rule model and compared this rate across conditions and groups. All groups increased their learning rate in the volatile condition compared to the stable condition. Unexpectedly, there was no effect of group and no interaction between group and condition. Thus, autistic children used information about the statistics of the reward environment to guide their decisions to a similar extent as typically developing children and adults. These results help constrain predictive coding accounts of autism by demonstrating that autism is not characterized by uniform differences in the weighting of prediction error. © 2016

  12. What Happened to Paul? Manifestation of Abnormal Pain Response for Individuals With Autism Spectrum Disorder.

    Science.gov (United States)

    Goldschmidt, Janice

    2017-07-01

    During the progression of a pilot nutrition intervention designed to teach cooking skills to young adults with autism spectrum disorder (ASD), one participant-Paul-fell in the parking lot. Prior to the accident, Paul had been making significant gains in the program and had communicated in a number of ways his enthusiasm. After his accident, which resulted in broken and dislocated bones in his ankle, his demeanor was dramatically altered, program gains were lost, and staff noted the appearance of many new challenging behaviors. This article analyzes Paul's behavior in reference to the pain response in autism. For some time, it was believed that many individuals with ASD did not experience pain based on anecdotal reports of how individuals responded to injury with seeming indifference. This view has given way of late to a more nuanced understanding of how atypical sensory processing and stimulus over-selectivity spill over into pain pathways and pain amplification mechanisms. The consequence is not a reduction in pain sensation, but a different expression of pain, determined by that individual's particular communicative, cognitive, or physiological challenges. From this perspective, many of the disruptive and harmful behaviors that emerged after Paul's accident can be seen as a delayed response to the incident. This article concludes by arguing that professionals across all domains of health care need to begin to see behavior as communicative for those with ASD. This is particularly true of changes in behavior, which can be significant indicators of health care problems rather than something to be dismissed as another manifestation of the condition.

  13. Quantum Kramers model: Corrections to the linear response theory for continuous bath spectrum

    Science.gov (United States)

    Rips, Ilya

    2017-01-01

    Decay of the metastable state is analyzed within the quantum Kramers model in the weak-to-intermediate dissipation regime. The decay kinetics in this regime is determined by energy exchange between the unstable mode and the stable modes of thermal bath. In our previous paper [Phys. Rev. A 42, 4427 (1990), 10.1103/PhysRevA.42.4427], Grabert's perturbative approach to well dynamics in the case of the discrete bath [Phys. Rev. Lett. 61, 1683 (1988), 10.1103/PhysRevLett.61.1683] has been extended to account for the second order terms in the classical equations of motion (EOM) for the stable modes. Account of the secular terms reduces EOM for the stable modes to those of the forced oscillator with the time-dependent frequency (TDF oscillator). Analytic expression for the characteristic function of energy loss of the unstable mode has been derived in terms of the generating function of the transition probabilities for the quantum forced TDF oscillator. In this paper, the approach is further developed and applied to the case of the continuous frequency spectrum of the bath. The spectral density functions of the bath of stable modes are expressed in terms of the dissipative properties (the friction function) of the original bath. They simplify considerably for the one-dimensional systems, when the density of phonon states is constant. Explicit expressions for the fourth order corrections to the linear response theory result for the characteristic function of the energy loss and its cumulants are obtained for the particular case of the cubic potential with Ohmic (Markovian) dissipation. The range of validity of the perturbative approach in this case is determined (γ /ωbrate for the quantum and for the classical Kramers models. Results for the classical escape rate are in very good agreement with the numerical simulations for high barriers. The results can serve as an additional proof of the robustness and accuracy of the linear response theory.

  14. Vehicle Lightweighting: Mass Reduction Spectrum Analysis and Process Cost Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Mascarin, Anthony [IBIS Associates, Inc., Waltham, MA (United States); Hannibal, Ted [IBIS Associates, Inc., Waltham, MA (United States); Raghunathan, Anand [Energetics Inc., Columbia, MD (United States); Ivanic, Ziga [Energetics Inc., Columbia, MD (United States); Clark, Michael [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-03-01

    The U.S. Department of Energy’s Vehicle Technologies Office, Materials area commissioned a study to model and assess manufacturing economics of alternative design and production strategies for a series of lightweight vehicle concepts. In the first two phases of this effort examined combinations of strategies aimed at achieving strategic targets of 40% and a 45% mass reduction relative to a standard North American midsize passenger sedan at an effective cost of $3.42 per pound (lb) saved. These results have been reported in the Idaho National Laboratory report INL/EXT-14-33863 entitled Vehicle Lightweighting: 40% and 45% Weight Savings Analysis: Technical Cost Modeling for Vehicle Lightweighting published in March 2015. The data for these strategies were drawn from many sources, including Lotus Engineering Limited and FEV, Inc. lightweighting studies, U.S. Department of Energy-funded Vehma International of America, Inc./Ford Motor Company Multi-Material Lightweight Prototype Vehicle Demonstration Project, the Aluminum Association Transportation Group, many United States Council for Automotive Research’s/United States Automotive Materials Partnership LLC lightweight materials programs, and IBIS Associates, Inc.’s decades of experience in automotive lightweighting and materials substitution analyses.

  15. Vehicle Lightweighting: Mass Reduction Spectrum Analysis and Process Cost Modeling

    International Nuclear Information System (INIS)

    Mascarin, Anthony; Hannibal, Ted; Raghunathan, Anand; Ivanic, Ziga; Clark, Michael

    2016-01-01

    The U.S. Department of Energy's Vehicle Technologies Office, Materials area commissioned a study to model and assess manufacturing economics of alternative design and production strategies for a series of lightweight vehicle concepts. In the first two phases of this effort examined combinations of strategies aimed at achieving strategic targets of 40% and a 45% mass reduction relative to a standard North American midsize passenger sedan at an effective cost of $3.42 per pound (lb) saved. These results have been reported in the Idaho National Laboratory report INL/EXT-14-33863 entitled Vehicle Lightweighting: 40% and 45% Weight Savings Analysis: Technical Cost Modeling for Vehicle Lightweighting published in March 2015. The data for these strategies were drawn from many sources, including Lotus Engineering Limited and FEV, Inc. lightweighting studies, U.S. Department of Energy-funded Vehma International of America, Inc./Ford Motor Company Multi-Material Lightweight Prototype Vehicle Demonstration Project, the Aluminum Association Transportation Group, many United States Council for Automotive Research's/United States Automotive Materials Partnership LLC lightweight materials programs, and IBIS Associates, Inc.'s decades of experience in automotive lightweighting and materials substitution analyses.

  16. Image enhancement of x-ray microscope using frequency spectrum analysis

    International Nuclear Information System (INIS)

    Li Wenjie; Chen Jie; Tian Jinping; Zhang Xiaobo; Liu Gang; Tian Yangchao; Liu Yijin; Wu Ziyu

    2009-01-01

    We demonstrate a new method for x-ray microscope image enhancement using frequency spectrum analysis. Fine sample characteristics are well enhanced with homogeneous visibility and better contrast from single image. This method is easy to implement and really helps to improve the quality of image taken by our imaging system.

  17. Image enhancement of x-ray microscope using frequency spectrum analysis

    Energy Technology Data Exchange (ETDEWEB)

    Li Wenjie; Chen Jie; Tian Jinping; Zhang Xiaobo; Liu Gang; Tian Yangchao [National Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei, Anhui 230029 (China); Liu Yijin; Wu Ziyu, E-mail: wuzy@ihep.ac.c, E-mail: ychtian@ustc.edu.c [Institute of High Energy Physics, Chinese Academy of Science, Beijing 100049 (China)

    2009-09-01

    We demonstrate a new method for x-ray microscope image enhancement using frequency spectrum analysis. Fine sample characteristics are well enhanced with homogeneous visibility and better contrast from single image. This method is easy to implement and really helps to improve the quality of image taken by our imaging system.

  18. Innovative Technology-Based Interventions for Autism Spectrum Disorders: A Meta-Analysis

    Science.gov (United States)

    Grynszpan, Ouriel; Weiss, Patrice L.; Perez-Diaz, Fernando; Gal, Eynat

    2014-01-01

    This article reports the results of a meta-analysis of technology-based intervention studies for children with autism spectrum disorders. We conducted a systematic review of research that used a pre-post design to assess innovative technology interventions, including computer programs, virtual reality, and robotics. The selected studies provided…

  19. Quantitative Evaluation of gamma-Spectrum Analysis Methods using IAEA Test Spectra

    DEFF Research Database (Denmark)

    Nielsen, Sven Poul

    1982-01-01

    A description is given of a γ-spectrum analysis method based on nonlinear least-squares fitting. The quality of the method is investigated by using statistical tests on the results from analyses of IAEA test spectra. By applying an empirical correction factor of 0.75 to the calculated peak-area u...

  20. Android application and REST server system for quasar spectrum presentation and analysis

    Science.gov (United States)

    Wasiewicz, P.; Pietralik, K.; Hryniewicz, K.

    2017-08-01

    This paper describes the implementation of a system consisting of a mobile application and RESTful architecture server intended for the analysis and presentation of quasars' spectrum. It also depicts the quasar's characteristics and significance to the scientific community, the source for acquiring astronomical objects' spectral data, used software solutions as well as presents the aspect of Cloud Computing and various possible deployment configurations.

  1. Spectrum analysis of national greenhouse gas emission: a case study of Germany

    Energy Technology Data Exchange (ETDEWEB)

    Su, Meirong [Dongguan University of Technology, School of Chemistry and Environmental Engineering, Dongguan, Guangdong Province (China); Beijing Normal University, State Key Joint Laboratory of Environment Simulation and Pollution Control, School of Environment, Beijing (China); Technical University of Munich, Strategic Landscape Planning and Management, Freising (Germany); Pauleit, Stephan; Xu, Chao [Technical University of Munich, Strategic Landscape Planning and Management, Freising (Germany)

    2016-10-15

    It is essential to abstract the key information from accounting results of greenhouse gas (GHG) emissions because it can provide a highly generalized and clear picture of GHG emissions, which is especially helpful for the public and policy makers. To clearly display the composition of GHG emissions, the concept of spectrum analysis is introduced and defined in this paper. Next, a multilayer analysis framework for national GHG emissions was proposed, which is represented by a pyramid of three layers: total emissions (first layer), emissions decomposed by gas type or sector (second layer), and emissions decomposed by both gas type and sector (third layer). Based on the analysis results from the first to third layers, the main compositional information of national GHG emissions was gradually summarized and analyzed until a spectrum of GHG emissions was acquired. The spectrum of GHG emissions displays the compositional structure of national GHG emissions in the different layers, which is helpful in identifying priorities for emissions reduction. A case study of Germany's GHG emissions during 1990-2012 was conducted, which indicated that CO{sub 2} and the energy sector were the biggest contributors to the total GHG emissions. Some suggestions for reducing GHG emissions are offered based on the obtained results. And the potential development of spectrum analysis for GHG emissions is also expected from aspects of both research and technology. (orig.)

  2. Effects of Physical Exercise on Autism Spectrum Disorders: A Meta-Analysis

    Science.gov (United States)

    Sowa, Michelle; Meulenbroek, Ruud

    2012-01-01

    It is generally agreed that regular physical exercise promotes physical and mental health, but what are the benefits in people with Autism Spectrum Disorders (ASD)? This meta-analysis evaluates 16 behavioural studies reporting on a total of 133 children and adults with various variants of the syndrome who were offered structured physical…

  3. Formation of the Actor's/Speaker's Formant: A Study Applying Spectrum Analysis and Computer Modeling

    Czech Academy of Sciences Publication Activity Database

    Leino, T.; Laukkanen, A. M.; Radolf, Vojtěch

    2011-01-01

    Roč. 25, č. 2 (2011), s. 150-158 ISSN 0892-1997 R&D Projects: GA ČR GA101/08/1155 Institutional research plan: CEZ:AV0Z20760514 Keywords : vocal exercising * voice quality * spectrum analysis * mathematical modeling Subject RIV: BI - Acoustics Impact factor: 1.390, year: 2011

  4. Video Modeling for Children and Adolescents with Autism Spectrum Disorder: A Meta-Analysis

    Science.gov (United States)

    Thompson, Teresa Lynn

    2014-01-01

    The objective of this research was to conduct a meta-analysis to examine existing research studies on video modeling as an effective teaching tool for children and adolescents diagnosed with Autism Spectrum Disorder (ASD). Study eligibility criteria included (a) single case research design using multiple baselines, alternating treatment designs,…

  5. Spectrum analysis of national greenhouse gas emission: a case study of Germany

    International Nuclear Information System (INIS)

    Su, Meirong; Pauleit, Stephan; Xu, Chao

    2016-01-01

    It is essential to abstract the key information from accounting results of greenhouse gas (GHG) emissions because it can provide a highly generalized and clear picture of GHG emissions, which is especially helpful for the public and policy makers. To clearly display the composition of GHG emissions, the concept of spectrum analysis is introduced and defined in this paper. Next, a multilayer analysis framework for national GHG emissions was proposed, which is represented by a pyramid of three layers: total emissions (first layer), emissions decomposed by gas type or sector (second layer), and emissions decomposed by both gas type and sector (third layer). Based on the analysis results from the first to third layers, the main compositional information of national GHG emissions was gradually summarized and analyzed until a spectrum of GHG emissions was acquired. The spectrum of GHG emissions displays the compositional structure of national GHG emissions in the different layers, which is helpful in identifying priorities for emissions reduction. A case study of Germany's GHG emissions during 1990-2012 was conducted, which indicated that CO_2 and the energy sector were the biggest contributors to the total GHG emissions. Some suggestions for reducing GHG emissions are offered based on the obtained results. And the potential development of spectrum analysis for GHG emissions is also expected from aspects of both research and technology. (orig.)

  6. Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification

    NARCIS (Netherlands)

    de Brouwer, Sara; de Preter, Katleen; Kumps, Candy; Zabrocki, Piotr; Porcu, Michaël; Westerhout, Ellen M.; Lakeman, Arjan; Vandesompele, Jo; Hoebeeck, Jasmien; van Maerken, Tom; de Paepe, Anne; Laureys, Geneviève; Schulte, Johannes H.; Schramm, Alexander; van den Broecke, Caroline; Vermeulen, Joëlle; van Roy, Nadine; Beiske, Klaus; Renard, Marleen; Noguera, Rosa; Delattre, Olivier; Janoueix-Lerosey, Isabelle; Kogner, Per; Martinsson, Tommy; Nakagawara, Akira; Ohira, Miki; Caron, Huib N.; Eggert, Angelika; Cools, Jan; Versteeg, Rogier; Speleman, Frank

    2010-01-01

    Purpose: Activating mutations of the anaplastic lymphoma kinase (ALK) were recently described in neuroblastoma. We carried out a meta-analysis of 709 neuroblastoma tumors to determine their frequency and mutation spectrum in relation to genomic and clinical parameters, and studied the prognostic

  7. [Analysis of fluorescence spectrum of petroleum-polluted water].

    Science.gov (United States)

    Huang, Miao-Fen; Song, Qing-Jun; Xing, Xu-Feng; Jian, Wei-Jun; Liu, Yuan; Zhao, Zu-Long

    2014-09-01

    In four ratio experiments, natural waters, sampled from the mountain reservoir and the sea water around Dalian city, were mixed with the sewage from petroleum refinery and petroleum exploitation plants. The fluorescence spectra of water samples containing only chromophoric dissolved organic matters(CDOM), samples containing only petroleum, and samples containing a mixture of petroleum and CDOM were analyzed, respectively. The purpose of this analysis is to provide a basis for determining the contribution of petroleum substances and CDOM to the total absorption coefficient of the petroleum-contaminated water by using fluorescence technique. The results showed that firstly, CDOM in seawater had three main fluorescence peaks at Ex: 225-230 nm/Em: 320-330 nm, Ex: 280 nm/Em: 340 nm and Ex: 225-240 nm/Em: 430-470 nm, respectively, and these may arise from the oceanic chlorophyll. CDOM in natural reservoir water had two main fluorescence peaks at EX: 240- 260 nm/Em: 420-450 nm and Ex: 310~350 nm/Em: 420--440 nm, respectively, and these may arise from the terrestrial sources; secondly, the water samples containing only petroleum extracted with n-hexane had one to three fluorescence spectral peaksat Ex: 220-240 nm/Em: 320-340 nm, Ex: 270-290 nm/Em: 310-340 nm and Ex: 220-235 nm/Em: 280-310 nm, respectively, caused by their hydrocarbon component; finally, the water samples containing both petroleum and CDOM showed a very strong fluorescence peak at Ex: 230-250 nm/Em: 320-370 nm, caused by the combined effect of CDOM and petroleum hydrocarbons.

  8. The analysis of results of comparison test for radionuclides measurement through γ spectrum analysis from 2007 to 2012

    International Nuclear Information System (INIS)

    Wu Jialong; He Jian; Sun Wei; Wang Yun

    2013-01-01

    In order to test the capability of radionuclides measurement through γ spectrum analysis and improve the ability of the technicians by inter-laboratory comparison test, Gansu Center for Disease Prevention and Control participated in the comparison test organized by China Center for Disease Prevention and Control continuously from 2007 to 2012. All of the measured values are within the scope of qualified, and the relative deviation of measured value in the entire comparison tests is range from -16.31% to 11.83%.The results show that the equipment for γ spectrum measurement works normally, the analysis methods used for radioactive nuclide measuring is correct and the data in issued test report is accurate and reliable. The ability of the γ spectrum analysis satisfies the requirements of China Metrology Accreditation and the occupational health technical service. (authors)

  9. Using module analysis for multiple choice responses

    DEFF Research Database (Denmark)

    Brewe, Eric; Bruun, Jesper; Bearden, Ian

    2016-01-01

    We describe a methodology for carrying out a network analysis of Force Concept Inventory (FCI) responses that aims to identify communities of incorrect responses. This method first treats FCI responses as a bipartite, student X response, network. We then use Locally Adaptive Network Sparsificatio...

  10. The effects of intranasal oxytocin on reward circuitry responses in children with autism spectrum disorder.

    Science.gov (United States)

    Greene, R K; Spanos, M; Alderman, C; Walsh, E; Bizzell, J; Mosner, M G; Kinard, J L; Stuber, G D; Chandrasekhar, T; Politte, L C; Sikich, L; Dichter, G S

    2018-03-27

    Intranasal oxytocin (OT) has been shown to improve social communication functioning of individuals with autism spectrum disorder (ASD) and, thus, has received considerable interest as a potential ASD therapeutic agent. Although preclinical research indicates that OT modulates the functional output of the mesocorticolimbic dopamine system that processes rewards, no clinical brain imaging study to date has examined the effects of OT on this system using a reward processing paradigm. To address this, we used an incentive delay task to examine the effects of a single dose of intranasal OT, versus placebo (PLC), on neural responses to social and nonsocial rewards in children with ASD. In this placebo-controlled double-blind study, 28 children and adolescents with ASD (age: M = 13.43 years, SD = 2.36) completed two fMRI scans, one after intranasal OT administration and one after PLC administration. During both scanning sessions, participants completed social and nonsocial incentive delay tasks. Task-based neural activation and connectivity were examined to assess the impact of OT relative to PLC on mesocorticolimbic brain responses to social and nonsocial reward anticipation and outcomes. Central analyses compared the OT and PLC conditions. During nonsocial reward anticipation, there was greater activation in the right nucleus accumbens (NAcc), left anterior cingulate cortex (ACC), bilateral orbital frontal cortex (OFC), left superior frontal cortex, and right frontal pole (FP) during the OT condition relative to PLC. Alternatively, during social reward anticipation and outcomes, there were no significant increases in brain activation during the OT condition relative to PLC. A Treatment Group × Reward Condition interaction revealed relatively greater activation in the right NAcc, right caudate nucleus, left ACC, and right OFC during nonsocial relative to social reward anticipation during the OT condition relative to PLC. Additionally, these analyses revealed

  11. [Analysis of the Muscle Fatigue Based on Band Spectrum Entropy of Multi-channel Surface Electromyography].

    Science.gov (United States)

    Liu, Jian; Zou, Renling; Zhang, Dongheng; Xu, Xiulin; Hu, Xiufang

    2016-06-01

    Exercise-induced muscle fatigue is a phenomenon that the maximum voluntary contraction force or power output of muscle is temporarily reduced due to muscular movement.If the fatigue is not treated properly,it will bring about a severe injury to the human body.With multi-channel collection of lower limb surface electromyography signals,this article analyzes the muscle fatigue by adoption of band spectrum entropy method which combined electromyographic signal spectral analysis and nonlinear dynamics.The experimental result indicated that with the increase of muscle fatigue,muscle signal spectrum began to move to low frequency,the energy concentrated,the system complexity came down,and the band spectrum entropy which reflected the complexity was also reduced.By monitoring the entropy,we can measure the degree of muscle fatigue,and provide an indicator to judge fatigue degree for the sports training and clinical rehabilitation training.

  12. Heightened brain response to pain anticipation in high-functioning adults with autism spectrum disorder.

    Science.gov (United States)

    Gu, Xiaosi; Zhou, Thomas J; Anagnostou, Evdokia; Soorya, Latha; Kolevzon, Alexander; Hof, Patrick R; Fan, Jin

    2018-03-01

    Autism spectrum disorder (ASD) is marked by both socio-communicative difficulties and abnormalities in sensory processing. Much of the work on sensory deficits in ASD has focused on tactile sensations and the perceptual aspects of somatosensation, such as encoding of stimulus intensity and location. Although aberrant pain processing has often been noted in clinical observations of patients with ASD, it remains largely uninvestigated. Importantly, the neural mechanism underlying higher order cognitive aspects of pain processing such as pain anticipation also remains unknown. Here we examined both pain perception and anticipation in high-functioning adults with ASD and matched healthy controls (HC) using an anticipatory pain paradigm in combination with functional magnetic resonance imaging (fMRI) and concurrent skin conductance response (SCR) recording. Participants were asked to choose a level of electrical stimulation that would feel moderately painful to them. Compared to HC group, ASD group chose a lower level of stimulation prior to fMRI. However, ASD participants showed greater activation in both rostral and dorsal anterior cingulate cortex during the anticipation of stimulation, but not during stimulation delivery. There was no significant group difference in insular activation during either pain anticipation or perception. However, activity in the left anterior insula correlated with SCR during pain anticipation. Taken together, these results suggest that ASD is marked with aberrantly higher level of sensitivity to upcoming aversive stimuli, which may reflect abnormal attentional orientation to nociceptive signals and a failure in interoceptive inference. © 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  13. Seismic Response Analysis of Assembled Reactor Vessel Internals

    International Nuclear Information System (INIS)

    Je, Sang-Yun; Chang, Yoon-Suk; Kang, Sung-Sik

    2015-01-01

    RVIs (Reactor Vessel Internals) perform important safe-related functions such as upholding the nuclear fuel assembly as well as providing the coolant passage of the reactor core and supporting the control rod drive mechanism. Therefore, the components including RVIs have to be designed and constructed taking into account the structural integrity under various accident scenarios. The reliable seismic analysis is essentially demanded to maintain the safe-related functions of RVIs. In this study, a modal analysis was performed based on the previous researches to examine values of frequencies, mode shapes and participation factors. Subsequently, the structural integrity respecting to the earthquake was evaluated through a response spectrum analysis by using the output variables of modal analysis. In this study, the structural integrity of the assembled RVIs was carried out against the seismic event via the modal and response spectrum analyses. Even though 287MPa of the maximum stress value occurred at the connected region between UGS and CSA, which was lower than its allowable value. At present, fluid-structure interaction effects are being examined for further realistic simulation, which will be reported in the near future

  14. Performance Analysis of Ad Hoc Dispersed Spectrum Cognitive Radio Networks over Fading Channels

    Directory of Open Access Journals (Sweden)

    Mohammad Muneer

    2011-01-01

    Full Text Available Cognitive radio systems can utilize dispersed spectrum, and thus such approach is known as dispersed spectrum cognitive radio systems. In this paper, we first provide the performance analysis of such systems over fading channels. We derive the average symbol error probability of dispersed spectrum cognitive radio systems for two cases, where the channel for each frequency diversity band experiences independent and dependent Nakagami- fading. In addition, the derivation is extended to include the effects of modulation type and order by considering M-ary phase-shift keying ( -PSK and M-ary quadrature amplitude modulation -QAM schemes. We then consider the deployment of such cognitive radio systems in an ad hoc fashion. We consider an ad hoc dispersed spectrum cognitive radio network, where the nodes are assumed to be distributed in three dimension (3D. We derive the effective transport capacity considering a cubic grid distribution. Numerical results are presented to verify the theoretical analysis and show the performance of such networks.

  15. Spectrum analysis in lead spectrometer for isotopic fissile assay in used fuel

    International Nuclear Information System (INIS)

    Lee, Y.D.; Park, C.J.; Kim, H.D.; Song, K.C.

    2014-01-01

    The LSDS system is under development for analyzing isotopic fissile content applicable in a hot cell for the pyro process. The fuel assay area and nuclear material composition were selected for simulation. The source mechanism for efficient neutron generation was also determined. A neutron is produced at the Ta target by hitting it from accelerated electron. The parameters for an electron accelerator are being researched for cost effectiveness, easy maintenance, and compact size. The basic principle of LSDS is that isotopic fissile has its own fission structure below the unresolved resonance region. The source neutron interacts with a lead medium and produces continuous neutron energy, which generates dominant fission at each fissile. Therefore, a spectrum analysis is very important at a lead medium and fuel area for system working. The energy spectrum with respect to slowing down energy and the energy resolution were investigated in lead. A spectrum analysis was done by the existence of surrounding detectors. In particular, high resonance energy was considered. The spectrum was well organized at each slowing down energy and the energy resolution was acceptable to distinguish isotopic fissile fissions. Additionally, LSDS is applicable for the optimum design of spent fuel storage and management.The isotopic fissile content assay will increase the transparency and credibility for spent fuel storage and its re-utilization, as demanded internationally. (author)

  16. Generation of spectrum compatible accelerograms for seismic analysis of prototype fast breeder reactor

    International Nuclear Information System (INIS)

    Selvaraj, T.; Chellapandi, P.; Chetal, S.C.

    2003-01-01

    For the seismic design of nuclear power plants, time history of earthquake ground motion is required basically to generate time histories at various floors of nuclear island as well as at the component support locations. From such time histories, floor response spectra (FRS) can be generated. The basic input is specified as site dependent response spectra (SDRS), from which a set of uncorrelated time histories is generated whose own response spectrum matches with the design response spectra. These time histories have got a great impact on the structural design and economy. For Kalpakkam, the site for PFBR, the seismic input is defined in terms of SDRS for various damping values and its shapes have been arrived already. Synthetic accelerograms have been generated such that the time-history generated response spectrum (THRS) closely matches the SDRS for 5% of critical damping. Time histories have been developed using CASTEM 2000, a multi purpose FE code. This paper deals with the generation methodology and their compliance with ASCE 4-98. (author)

  17. Analysis of Bi-directional Effects on the Response of a Seismic Base Isolation System

    International Nuclear Information System (INIS)

    Park, Hyung-Kui; Kim, Jung-Han; Kim, Min Kyu; Choi, In-Kil

    2014-01-01

    The floor response spectrum depends on the height of the floor of the structure. Also FRS depends on the characteristics of the seismic base isolation system such as the natural frequency, damping ratio. In the previous study, the floor response spectrum of the base isolated structure was calculated for each axis without considering bi-directional effect. However, the shear behavior of the seismic base isolation system of two horizontal directions are correlated each other by the bi-directional effects. If the shear behavior of the seismic isolation system changes, it can influence the floor response spectrum and displacement response of isolators. In this study, the analysis of a bi-directional effect on the floor response spectrum was performed. In this study, the response of the seismic base isolation system based on the bi-directional effects was analyzed. By analyzing the time history result, while there is no alteration in the maximum shear force of seismic base isolation system, it is confirmed that the shear force is generally more decreased in a one-directional that in a two-directional in most parts. Due to the overall decreased shear force, the floor response spectrum is more reduced in a two-directional than in a one-directional

  18. Vibration Spectrum Analysis for Indicating Damage on Turbine and Steam Generator Amurang Unit 1

    Directory of Open Access Journals (Sweden)

    Beny Cahyono

    2017-12-01

    Full Text Available Maintenance on machines is a mandatory asset management activity to maintain asset reliability in order to reduce losses due to failure. 89% of defects have random failure mode, the proper maintenance method is predictive maintenance. Predictive maintenance object in this research is Steam Generator Amurang Unit 1, which is predictive maintenance is done through condition monitoring in the form of vibration analysis. The conducting vibration analysis on Amurang Unit 1 Steam Generator is because vibration analysis is very effective on rotating objects. Vibration analysis is predicting the damage based on the vibration spectrum, where the vibration spectrum is the result of separating time-based vibrations and simplifying them into vibrations based on their frequency domain. The transformation of time-domain-wave into frequency-domain-wave is using the application of FFT, namely AMS Machinery. The measurement of vibration value is done on turbine bearings and steam generator of Unit 1 Amurang using Turbine Supervisory Instrument and CSI 2600 instrument. The result of this research indicates that vibration spectrum from Unit 1 Amurang Power Plant indicating that there is rotating looseness, even though the vibration value does not require the Unit 1 Amurang Power Plant to stop operating (shut down. This rotating looseness, at some point, can produce some indications that similar with the unbalance. In order to avoid more severe vibrations, it is necessary to do inspection on the bearings in the Amurang Unit 1 Power Plant.

  19. Can Autism Spectrum Disorders and Social Anxiety Disorders Be Differentiated by the Social Responsiveness Scale in Children and Adolescents?

    Science.gov (United States)

    Cholemkery, Hannah; Mojica, Laura; Rohrmann, Sonja; Gensthaler, Angelika; Freitag, Christine M.

    2014-01-01

    Autism spectrum disorder (ASD) as well as social phobia (SP), and selective mutism (SM) are characterised by impaired social interaction. We assessed the validity of the Social Responsiveness Scale (SRS) to differentiate between ASD, and SP/SM. Raw scores were compared in 6-18 year old individuals with ASD (N = 60), SP (N = 38), SM (N = 43), and…

  20. Functional pitch of a liver: fatty liver disease diagnosis with photoacoustic spectrum analysis

    Science.gov (United States)

    Xu, Guan; Meng, Zhuoxian; Lin, Jiandie; Carson, Paul; Wang, Xueding

    2014-03-01

    To provide more information for classification and assessment of biological tissues, photoacoustic spectrum analysis (PASA) moves beyond the quantification of the intensities of the photoacoustic (PA) signals by the use of the frequency-domain power distribution, namely power spectrum, of broadband PA signals. The method of PASA quantifies the linear-fit to the power spectrum of the PA signals from a biological tissue with 3 parameters, including intercept, midband-fit and slope. Intercept and midband-fit reflect the total optical absorption of the tissues whereas slope reflects the heterogeneity of the tissue structure. Taking advantage of the optical absorption contrasts contributed by lipid and blood at 1200 and 532 nm, respectively and the heterogeneous tissue microstructure in fatty liver due to the lipid infiltration, we investigate the capability of PASA in identifying histological changes of fatty livers in mouse model. 6 and 9 pairs of normal and fatty liver tissues from rat models were examined by ex vivo experiment with a conventional rotational PA measurement system. One pair of rat models with normal and fatty livers was examined non-invasively and in situ with our recently developed ultrasound and PA parallel imaging system. The results support our hypotheses that the spectrum analysis of PA signals can provide quantitative measures of the differences between the normal and fatty liver tissues and that part of the PA power spectrum can suffice for characterization of microstructures in biological tissues. Experimental results also indicate that the vibrational absorption peak of lipid at 1200nm could facilitate fatty liver diagnosis.

  1. Repetitive transcranial magnetic stimulation for hallucination in schizophrenia spectrum disorders: A meta-analysis.

    Science.gov (United States)

    Zhang, Yingli; Liang, Wei; Yang, Shichang; Dai, Ping; Shen, Lijuan; Wang, Changhong

    2013-10-05

    This study assessed the efficacy and tolerability of repetitive transcranial magnetic stimulation for treatment of auditory hallucination of patients with schizophrenia spectrum disorders. Online literature retrieval was conducted using PubMed, ISI Web of Science, EMBASE, Medline and Cochrane Central Register of Controlled Trials databases from January 1985 to May 2012. Key words were "transcranial magnetic stimulation", "TMS", "repetitive transcranial magnetic stimulation", and "hallucination". Selected studies were randomized controlled trials assessing therapeutic efficacy of repetitive transcranial magnetic stimulation for hallucination in patients with schizophrenia spectrum disorders. Experimental intervention was low-frequency repetitive transcranial magnetic stimulation in left temporoparietal cortex for treatment of auditory hallucination in schizophrenia spectrum disorders. Control groups received sham stimulation. The primary outcome was total scores of Auditory Hallucinations Rating Scale, Auditory Hallucination Subscale of Psychotic Symptom Rating Scale, Positive and Negative Symptom Scale-Auditory Hallucination item, and Hallucination Change Scale. Secondary outcomes included response rate, global mental state, adverse effects and cognitive function. Seventeen studies addressing repetitive transcranial magnetic stimulation for treatment of schizophrenia spectrum disorders were screened, with controls receiving sham stimulation. All data were completely effective, involving 398 patients. Overall mean weighted effect size for repetitive transcranial magnetic stimulation versus sham stimulation was statistically significant (MD = -0.42, 95%CI: -0.64 to -0.20, P = 0.000 2). Patients receiving repetitive transcranial magnetic stimulation responded more frequently than sham stimulation (OR = 2.94, 95%CI: 1.39 to 6.24, P = 0.005). No significant differences were found between active repetitive transcranial magnetic stimulation and sham stimulation for

  2. A Systematic Review and Meta-Analysis of Multiple Airborne Pollutants and Autism Spectrum Disorder.

    Directory of Open Access Journals (Sweden)

    Juleen Lam

    Full Text Available Exposure to ambient air pollution is widespread and may be detrimental to human brain development and a potential risk factor for Autism Spectrum Disorder (ASD. We conducted a systematic review of the human evidence on the relationship between ASD and exposure to all airborne pollutants, including particulate matter air pollutants and others (e.g. pesticides and metals.To answer the question: "is developmental exposure to air pollution associated with ASD?"We conducted a comprehensive search of the literature, identified relevant studies using inclusion/exclusion criteria pre-specified in our protocol (registered in PROSPERO, CRD # 42015017890, evaluated the potential risk of bias for each included study and identified an appropriate subset of studies to combine in a meta-analysis. We then rated the overall quality and strength of the evidence collectively across all air pollutants.Of 1,158 total references identified, 23 human studies met our inclusion criteria (17 case-control, 4 ecological, 2 cohort. Risk of bias was generally low across studies for most domains; study limitations were related to potential confounding and accuracy of exposure assessment methods. We rated the quality of the body of evidence across all air pollutants as "moderate." From our meta-analysis, we found statistically significant summary odds ratios (ORs of 1.07 (95% CI: 1.06, 1.08 per 10-μg/m3 increase in PM10 exposure (n = 6 studies and 2.32 (95% CI: 2.15, 2.51 per 10-μg/m3 increase in PM2.5 exposure (n = 3 studies. For pollutants not included in a meta-analysis, we collectively evaluated evidence from each study in rating the strength and quality of overall evidence considering factors such as inconsistency, imprecision, and evidence of dose-response. All included studies generally showed increased risk of ASD with increasing exposure to air pollution, although not consistently across all chemical components.After considering strengths and limitations of the body

  3. [Study on spectrum analysis of X-ray based on rotational mass effect in special relativity].

    Science.gov (United States)

    Yu, Zhi-Qiang; Xie, Quan; Xiao, Qing-Quan

    2010-04-01

    Based on special relativity, the formation mechanism of characteristic X-ray has been studied, and the influence of rotational mass effect on X-ray spectrum has been given. A calculation formula of the X-ray wavelength based upon special relativity was derived. Error analysis was carried out systematically for the calculation values of characteristic wavelength, and the rules of relative error were obtained. It is shown that the values of the calculation are very close to the experimental values, and the effect of rotational mass effect on the characteristic wavelength becomes more evident as the atomic number increases. The result of the study has some reference meaning for the spectrum analysis of characteristic X-ray in application.

  4. Polarimetry of coherent bremsstrahlung by analysis of the photon energy spectrum

    International Nuclear Information System (INIS)

    Darbinyan, S.; Hakobyan, H.; Jones, R.; Sirunyan, A.; Vartapetian, H.

    2005-01-01

    A method of coherent bremsstrahlung (CB) polarimetry based on the analysis of the shape of the photon energy spectrum is presented. The influence of a number of uncertainty sources, including the choice of atomic form-factors, has been analyzed. For a CB source consisting of a diamond radiator and multi-GeV electrons, an absolute accuracy of polarimetry at the level of 0.01-0.02 is attainable

  5. An Improved Biclustering Algorithm and Its Application to Gene Expression Spectrum Analysis

    OpenAIRE

    Qu, Hua; Wang, Liu-Pu; Liang, Yan-Chun; Wu, Chun-Guo

    2016-01-01

    Cheng and Church algorithm is an important approach in biclustering algorithms. In this paper, the process of the extended space in the second stage of Cheng and Church algorithm is improved and the selections of two important parameters are discussed. The results of the improved algorithm used in the gene expression spectrum analysis show that, compared with Cheng and Church algorithm, the quality of clustering results is enhanced obviously, the mining expression models are better, and the d...

  6. Analysis of the x-ray spectrum emitted by laser-produced plasma of dysprosium

    International Nuclear Information System (INIS)

    Marcus, Gilad; Louzon, Einat; Henis, Zohar; Maman, Shlomo; Mandelbaum, Pinchas

    2007-01-01

    A detailed analysis of the x-ray spectrum (5-10.2 A ring ) emitted by laser-produced plasma of dysprosium (Dy) is given using ab initio calculations with the HULLAC relativistic code and isoelectronic trends. Resonance 3d-4p, 3d-nf (n=4 to 7), 3p-4s, and 3p-4d transitions of Ni I-like Dy XXXIX and neighboring ion satellite transitions (from Dy XXXIV to Dy XL) are identified

  7. Mutation analysis of the NSD1 gene in patients with autism spectrum disorders and macrocephaly

    Directory of Open Access Journals (Sweden)

    Delorme Richard

    2007-11-01

    Full Text Available Abstract Background Sotos syndrome is an overgrowth syndrome characterized by macrocephaly, advanced bone age, characteristic facial features, and learning disabilities, caused by mutations or deletions of the NSD1 gene, located at 5q35. Sotos syndrome has been described in a number of patients with autism spectrum disorders, suggesting that NSD1 could be involved in other cases of autism and macrocephaly. Methods We screened the NSD1 gene for mutations and deletions in 88 patients with autism spectrum disorders and macrocephaly (head circumference 2 standard deviations or more above the mean. Mutation analysis was performed by direct sequencing of all exons and flanking regions. Dosage analysis of NSD1 was carried out using multiplex ligation-dependent probe amplification. Results We identified three missense variants (R604L, S822C and E1499G in one patient each, but none is within a functional domain. In addition, segregation analysis showed that all variants were inherited from healthy parents and in two cases were also present in unaffected siblings, indicating that they are probably nonpathogenic. No partial or whole gene deletions/duplications were observed. Conclusion Our findings suggest that Sotos syndrome is a rare cause of autism spectrum disorders and that screening for NSD1 mutations and deletions in patients with autism and macrocephaly is not warranted in the absence of other features of Sotos syndrome.

  8. Using the Autism-Spectrum Quotient to Measure Autistic Traits in Anorexia Nervosa: A Systematic Review and Meta-Analysis

    Science.gov (United States)

    Westwood, Heather; Eisler, Ivan; Mandy, William; Leppanen, Jenni; Treasure, Janet; Tchanturia, Kate

    2016-01-01

    Interest in the link between Autism Spectrum Disorder (ASD) and Anorexia Nervosa (AN) has led to estimates of the prevalence of autistic traits in AN. This systematic review and meta-analysis assessed the use of the Autism-Spectrum Quotient (AQ) or abbreviated version (AQ-10) to examine whether patients with AN have elevated levels of autistic…

  9. XMM-Newton observation of the NLS1 galaxy Ark 564. I. Spectral analysis of the time-average spectrum

    NARCIS (Netherlands)

    Papadakis, I.E.; Brinkmann, W.; Page, M.J.; McHardy, I.; Uttley, P.

    2007-01-01

    Context: .We present the results from the spectral analysis of the time-average spectrum of the Narrow Line Seyfert 1 (NLS1) galaxy Ark 564 from a ~100 ks XMM-Newton observation. Aims: .Our aim is to characterize accurately the shape of the time-average, X-ray continuum spectrum of the source and

  10. SAMPO 90 - High resolution interactive gamma spectrum analysis including automation with macros

    International Nuclear Information System (INIS)

    Aarnio, P.A.; Nikkinen, M.T.; Routti, J.T.

    1991-01-01

    SAMPO 90 is a high performance gamma spectrum analysis program for personal computers. It uses high resolution color graphics to display calibrations, spectra, fitting results as multiplet components, and analysis results. All the analysis phases can be done either under full interactive user control or by using macros for automated measurement and analysis sequences including the control of MCAs and sample changers. Semi-automated calibrations for peak shapes (Gaussian with exponential tails), detector efficiency, and energy are available with a possibility for user intervention through interactive graphics. Accurate peak area determination of even the most complex multiplets, of up to 32 components, is accomplished using linear, non-linear and mixed mode fitting, where the component energies and areas can be either frozen or allowed to float in arbitrary combinations. Nuclide identification is done using associated lines techniques which allow interference correction for fully overlapping peaks. Peaked Background Subtraction can be performed and Minimum Detectable Activities calculated. Attenuation corrections can be taken into account in detector efficiency calculation. The most common PC-based MCA spectrum formats (Canberra S100, Ortec ACE, Nucleus PCA, ND AccuSpec) are supported as well as ASCII spectrum files. A gamma-line library is included together with an editor for user configurable libraries. The analysis reports and program parameters are fully customizable. Function key macros can be used to automate the most common analysis procedures. Small batch type modules are additionally available for routine work. SAMPO 90 is a result of over twenty man years of programming and contains 25,000 lines of Fortran, 10,000 lines of C, and 12,000 lines of assembler

  11. Analysis of design floor response spectra and testing of the electrical systems

    International Nuclear Information System (INIS)

    Ambriashvili, Y.

    1996-01-01

    This report covers the following activities as foreseen according to the working plan of 'Atmoenergoproject': analysis of calculated floor response spectra used during the design of Kozloduy NPP and comparison with other spectra recommended for this NPP; analysis of floor response spectrum for the most important systems (reactor, main coolant loop, electrical systems); tests of main electrical systems and analysis of the results on seismic stability of those systems. Results of the response spectra analysis are given, some of the electrical systems are identified by the Kozloduy authorities to be analyzed in future according to the results of the test on seismicity

  12. SPECTRUM analysis of multispectral imagery in conjunction with wavelet/KLT data compression

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, J.N.; Brislawn, C.M.

    1993-12-01

    The data analysis program, SPECTRUM, is used for fusion, visualization, and classification of multi-spectral imagery. The raw data used in this study is Landsat Thematic Mapper (TM) 7-channel imagery, with 8 bits of dynamic range per channel. To facilitate data transmission and storage, a compression algorithm is proposed based on spatial wavelet transform coding and KLT decomposition of interchannel spectral vectors, followed by adaptive optimal multiband scalar quantization. The performance of SPECTRUM clustering and visualization is evaluated on compressed multispectral data. 8-bit visualizations of 56-bit data show little visible distortion at 50:1 compression and graceful degradation at higher compression ratios. Two TM images were processed in this experiment: a 1024 x 1024-pixel scene of the region surrounding the Chernobyl power plant, taken a few months before the reactor malfunction, and a 2048 x 2048 image of Moscow and surrounding countryside.

  13. Spectrum unfolding, sensitivity analysis and propagation of uncertainties with the maximum entropy deconvolution code MAXED

    CERN Document Server

    Reginatto, M; Neumann, S

    2002-01-01

    MAXED was developed to apply the maximum entropy principle to the unfolding of neutron spectrometric measurements. The approach followed in MAXED has several features that make it attractive: it permits inclusion of a priori information in a well-defined and mathematically consistent way, the algorithm used to derive the solution spectrum is not ad hoc (it can be justified on the basis of arguments that originate in information theory), and the solution spectrum is a non-negative function that can be written in closed form. This last feature permits the use of standard methods for the sensitivity analysis and propagation of uncertainties of MAXED solution spectra. We illustrate its use with unfoldings of NE 213 scintillation detector measurements of photon calibration spectra, and of multisphere neutron spectrometer measurements of cosmic-ray induced neutrons at high altitude (approx 20 km) in the atmosphere.

  14. A Bayesian analysis of inflationary primordial spectrum models using Planck data

    Science.gov (United States)

    Santos da Costa, Simony; Benetti, Micol; Alcaniz, Jailson

    2018-03-01

    The current available Cosmic Microwave Background (CMB) data show an anomalously low value of the CMB temperature fluctuations at large angular scales (l power is not explained by the minimal ΛCDM model, and one of the possible mechanisms explored in the literature to address this problem is the presence of features in the primordial power spectrum (PPS) motivated by the early universe physics. In this paper, we analyse a set of cutoff inflationary PPS models using a Bayesian model comparison approach in light of the latest CMB data from the Planck Collaboration. Our results show that the standard power-law parameterisation is preferred over all models considered in the analysis, which motivates the search for alternative explanations for the observed lack of power in the CMB anisotropy spectrum.

  15. Research on n-γ discrimination method based on spectrum gradient analysis of signals

    International Nuclear Information System (INIS)

    Luo Xiaoliang; Liu Guofu; Yang Jun; Wang Yueke

    2013-01-01

    Having discovered that there are distinct differences between the spectrum gradient of the output neutron and γ-ray signal from liquid scintillator detectors, this paper presented a n-γ discrimination method called spectrum gradient analysis (SGA) based on frequency-domain features of the pulse signals. The basic principle and feasibility of SGA method were discussed and the validity of n-γ discrimination results of SGA was verified by the associated particle neutron flight experiment. The discrimination performance of SGA was evaluated under different conditions of sampling rates ranging from 5 G/s to 250 M/s. The results show that SGA method exhibits insensitivity to noise, strong anti-interference ability, stable discrimination performance and lower amount of calculation in contrast with time-domain n-γ discrimination methods. (authors)

  16. Electromagnetic Spectrum Analysis and Its Influence on the Photoelectric Conversion Efficiency of Solar Cells.

    Science.gov (United States)

    Hu, Kexiang; Ding, Enjie; Wangyang, Peihua; Wang, Qingkang

    2016-06-01

    The electromagnetic spectrum and the photoelectric conversion efficiency of the silicon hexagonal nanoconical hole (SiHNH) arrays based solar cells is systematically analyzed according to Rigorous Coupled Wave Analysis (RCWA) and Modal Transmission Line (MTL) theory. An ultimate efficiency of the optimized SiHNH arrays based solar cell is up to 31.92% in consideration of the absorption spectrum, 4.52% higher than that of silicon hexagonal nanoconical frustum (SiHNF) arrays. The absorption enhancement of the SiHNH arrays is due to its lower reflectance and more supported guided-mode resonances, and the enhanced ultimate efficiency is insensitive to bottom diameter (D(bot)) of nanoconical hole and the incident angle. The result provides an additional guideline for the nanostructure surface texturing fabrication design for photovoltaic applications.

  17. An Analysis of Canadian Institute for Health Research Funding for Research on Autism Spectrum Disorder

    Directory of Open Access Journals (Sweden)

    R. Deonandan

    2016-01-01

    Full Text Available We examined patterns of Canadian Institute for Health Research (CIHR funding on autism spectrum disorder (ASD research. From 1999 to 2013, CIHR funded 190 ASD grants worth $48 million. Biomedical research received 43% of grants (46% of dollars, clinical research 27% (41%, health services 10% (7%, and population health research 8% (3%. The greatest number of grants was given in 2009, but 2003 saw the greatest amount. Funding is clustered in a handful of provinces and institutions, favouring biomedical research and disfavouring behavioural interventions, adaptation, and institutional response. Preference for biomedical research may be due to the detriment of clinical research.

  18. SAMPO 90 high resolution interactive gamma-spectrum analysis including automation with macros

    International Nuclear Information System (INIS)

    Aarnio, P.A.; Nikkinen, M.T.; Routti, J.T.

    1992-01-01

    SAMPO 90 is high performance gamma-spectrum analysis program for personal computers. It uses color graphics to display calibrations, spectra, fitting results as multiplet components, and analysis results. All the analysis phases can be done either under full interactive user control or macros and programmable function keys can be used for completely automated measurement and analysis sequences including the control of MACs and sample changers. Accurate peak area determination of even the most complex multiplets, of up to 32 components, is accomplished using linear and mixed mode fitting. Nuclide identification is done using associated lines techniques allowing interference correction for fully overlapping peaks. Peaked Background Subtraction can be performed and Minimum Detectable Activities calculated. The analysis reports and program parameters are fully customizable. (author) 13 refs.; 1 fig

  19. Response analysis of the dynamic excitation of hen eggs

    Directory of Open Access Journals (Sweden)

    Libor Severa

    2007-01-01

    Full Text Available Commercially produced hen eggs have been tested by means of dynamic excitation of the egg-shells with following analysis of their response. The falling steel ball have been chosen as a exciting instrument and the laser vibrometer have been used as a measuring device for the egg response. The reproductibility of the experiments has been relatively high and the surface velocity has been found to be significantly dependent on the position around the meridian. Analysed frequency spectrum has shown the peak frequency and frequency history. Proposed numerical model has demonstrated reasonable agreement with experimental results and can be used as an effective tool in modelling of analogous or similar experiments.

  20. Integration of auto analysis program of gamma spectrum and software and determination of element content in sample by k-zero method

    International Nuclear Information System (INIS)

    Trinh Quang Vinh; Truong Thi Hong Loan; Mai Van Nhon; Huynh Truc Phuong

    2014-01-01

    Integrating the gamma spectrum auto-analysis program with elemental analysis software by k-zero method is the objective for many researchers. This work is the first stepin building an auto analysis program of gamma spectrum, which includes modules of reading spectrum, displaying spectrum, calibrating energy of peak, smoothing spectrum, calculating peak area and determining content of elements in sample. Then, the results from the measurements of standard samples by a low level spectrometer using HPGe detector are compared to those of other gamma spectrum auto-analysis programs. (author)

  1. Proteomic analysis of chromate response in Staphylococcus ...

    African Journals Online (AJOL)

    user

    2012-04-18

    Apr 18, 2012 ... analysis was performed to identify proteins involved in chromate stress response of Staphylococcus saprophyticus .... Proteins were visualized by PharosFXTM molecular imager and scanner ..... Molecular dynamics of the.

  2. The analysis study of plutonium in the environmental sample by mass spectrum combined with isotopic dilution

    International Nuclear Information System (INIS)

    Han Jun; Fu Zhonghua; Mao Xingen; Meng Fanben

    2004-01-01

    The technology of the rhenium filament carbonization was used to increase the ionization efficiency in this paper. The plutonium in the environmental sample was analyzed by Mass Spectrum combined with isotope dilution. Analysis of the 239 Pu blank in the process: The analysis of 239 Pu from the chemical process was carried out in order to establish the influence of the 239 Pu introduced from the process. The analysis results were shown in Table 1 sample 1 was not gone through the process, sample 2 and sample 3 were gone through the process. It was clear that there was no influence of the 239 Pu from the process within the deviation. Results and Discussions: The environmental samples which were dealed with the chemical method were prepared the sample of mass spectrum, The atomic ratio of the 239 Pu and 242 Pu in the environmental samples was measured by Mass Spectrum. The atomic ratio in the tracer 242 Pu was 0.01476±0.00007.The results for nuclide content in environment were given in Table 2. The content of 239 Pu in the tracer was high, so the existing of 239 Pu in the environmental samples can be determined by the changing of the atomic ratio of 242 Pu to 239 Pu. It was clear that there was 239 Pu in the environmental samples except the cypress leaves-2 and the pine leaves-3 within the deviation, and the content of 239 Pu were given in Table 2. Conclusion: a. Plutonium was separated and purified from the impurity by the anion-exchange and the electrodeposition, it was possible to provide the eligible mass spectrum sample. b. The measurement of plutonium in the environmental samples was not influenced by the flow of the background in the experiment. c. As the technology of the rhenium carbonization was used to increase the ionization efficiency, the content of plutonium which was about 10 -13 g in the environmental sample could be quantitatively analyzed by Mass Spectrum combined with isotope dilution. (authors)

  3. Structural-Vibration-Response Data Analysis

    Science.gov (United States)

    Smith, W. R.; Hechenlaible, R. N.; Perez, R. C.

    1983-01-01

    Computer program developed as structural-vibration-response data analysis tool for use in dynamic testing of Space Shuttle. Program provides fast and efficient time-domain least-squares curve-fitting procedure for reducing transient response data to obtain structural model frequencies and dampings from free-decay records. Procedure simultaneously identifies frequencies, damping values, and participation factors for noisy multiple-response records.

  4. Sensor response time monitoring using noise analysis

    International Nuclear Information System (INIS)

    Hashemian, H.M.; Thie, J.A.; Upadhyaya, B.R.; Holbert, K.E.

    1988-01-01

    Random noise techniques in nuclear power plants have been developed for system surveillance and for analysis of reactor core dynamics. The noise signals also contain information about sensor dynamics, and this can be extracted using frequency, amplitude and time domain analyses. Even though noise analysis has been used for sensor response time testing in some nuclear power plants, an adequate validation of this method has never been carried out. This paper presents the results of limited work recently performed to examine the validity of the noise analysis for sensor response time testing in nuclear power plants. The conclusion is that noise analysis has the potential for detecting gross changes in sensor response but it cannot be used for reliable measurement of response time until more laboratory and field experience is accumulated. The method is more advantageous for testing pressure sensors than it is for temperature sensors. This is because: 1) for temperature sensors, a method called Loop Current Step Response test is available which is quantitatively more exact than noise analysis, 2) no method currently exists for on-line testing of pressure transmitters other than the Power-Interrupt test which is applicable only to force balance pressure transmitters, and 3) pressure sensor response time is affected by sensing line degradation which is inherently taken into account by testing with noise analysis. (author)

  5. Are Autistic Traits Measured Equivalently in Individuals With and Without An Autism Spectrum Disorder? An Invariance Analysis of the Autism Spectrum Quotient Short Form

    OpenAIRE

    Murray, Aja Louise; Booth, Tom; McKenzie, Karen; Kuenssberg, Renate; O’Donnell, Michael

    2014-01-01

    It is common to administer measures of autistic traits to those without autism spectrum disorders (ASDs) with, for example, the aim of understanding autistic personality characteristics in non-autistic individuals. Little research has examined the extent to which measures of autistic traits actually measure the same traits in the same way across those with and without an ASD. We addressed this question using a multi-group confirmatory factor invariance analysis of the Autism Quotient Short Fo...

  6. Applications of a broad-spectrum tool for conservation and fisheries analysis: aquatic gap analysis

    Science.gov (United States)

    McKenna, James E.; Steen, Paul J.; Lyons, John; Stewart, Jana S.

    2009-01-01

    Natural resources support all of our social and economic activities, as well as our biological existence. Humans have little control over most of the physical, biological, and sociological conditions dictating the status and capacity of natural resources in any particular area. However, the most rapid and threatening influences on natural resources typically are anthropogenic overuse and degradation. In addition, living natural resources (i.e., organisms) do not respect political boundaries, but are aware of their optimal habitat and environmental conditions. Most organisms have wider spatial ranges than the jurisdictional boundaries of environmental agencies that deal with them; even within those jurisdictions, information is patchy and disconnected. Planning and projecting effects of ecological management are difficult, because many organisms, habitat conditions, and interactions are involved. Conservation and responsible resource use involves wise management and manipulation of the aspects of the environment and biological communities that can be effectively changed. Tools and data sets that provide new insights and analysis capabilities can enhance the ability of resource managers to make wise decisions and plan effective, long-term management strategies. Aquatic gap analysis has been developed to provide those benefits. Gap analysis is more than just the assessment of the match or mis-match (i.e., gaps) between habitats of ecological value and areas with an appropriate level of environmental protection (e.g., refuges, parks, preserves), as the name suggests. Rather, a Gap Analysis project is a process which leads to an organized database of georeferenced information and previously available tools to examine conservation and other ecological issues; it provides a geographic analysis platform that serves as a foundation for aquatic ecological studies. This analytical tool box allows one to conduct assessments of all habitat elements within an area of interest

  7. Photon-response spectrum of surface barrier diodes on GaAssub(1-x)Psub(x) mixed crystals

    International Nuclear Information System (INIS)

    Omar, O.A.

    1981-07-01

    Surface barrier diodes have been prepared by chemical deposition of thin gold film on samples of GaAssub(1-x)Psub(x) with x=0.3. The spectrum of the photo-response over a spectral range covering the photo-injection from the metal and the intrinsic absorption regions of the semiconductor has been measured. From the photo-threshold corresponding to each region, the height of the energy barrier and the forbidden gap width of the semiconductor have been determined and are found to be 0.96 e.v. and 1.78 e.v. respectively for the investigated composition. (author)

  8. Physiological responses to social and nonsocial stimuli in neurotypical adults with high and low levels of autistic traits: implications for understanding nonsocial drive in autism spectrum disorders.

    Science.gov (United States)

    Singleton, Clarence J; Ashwin, Chris; Brosnan, Mark

    2014-12-01

    Researchers have suggested that the two primary cognitive features of autism spectrum disorder (ASD), a drive toward nonsocial processing and a reduced drive toward social processing, may be unrelated to each other in the neurotypical (NT) population and may therefore require separate explanations. Drive toward types of processing may be related to physiological arousal to categories of stimuli, such as social (e.g., faces) or nonsocial (e.g., trains). This study investigated how autistic traits in an NT population might relate to differences in physiological responses to nonsocial compared with social stimuli. NT participants were recruited to examine these differences in those with high vs. low degrees of ASD traits. Forty-six participants (21 male, 25 female) completed the Autism Spectrum Quotient (AQ) to measure ASD traits before viewing a series of 24 images while skin conductance response (SCR) was recorded. Images included six nonsocial, six social, six face-like cartoons, and six nonsocial (relating to participants' personal interests). Analysis revealed that those with a higher AQ had significantly greater SCR arousal to nonsocial stimuli than those with a low AQ, and the higher the AQ, the greater the difference between SCR arousal to nonsocial and social stimuli. This is the first study to identify the relationship between AQ and physiological response to nonsocial stimuli, and a relationship between physiological response to both social and nonsocial stimuli, suggesting that physiological response may underlie the atypical drive toward nonsocial processing seen in ASD, and that at the physiological level at least the social and nonsocial in ASD may be related to one another. © 2014 International Society for Autism Research, Wiley Periodicals, Inc.

  9. Repetitive transcranial magnetic stimulation for hallucination in schizophrenia spectrum disorders A meta-analysis***

    Institute of Scientific and Technical Information of China (English)

    Yingli Zhang; Wei Liang; Shichang Yang; Ping Dai; Lijuan Shen; Changhong Wang

    2013-01-01

    OBJECTIVE: This study assessed the efficacy and tolerability of repetitive transcranial magnetic stimulation for treatment of auditory hal ucination of patients with schizophrenia spectrum disorders. DATA SOURCES: Online literature retrieval was conducted using PubMed, ISI Web of Science, EMBASE, Medline and Cochrane Central Register of Control ed Trials databases from January 1985 to May 2012. Key words were “transcranial magnetic stimulation”, “TMS”, “repetitive transcranial magnetic stimulation”, and “hal ucination”. STUDY SELECTION: Selected studies were randomized control ed trials assessing therapeutic ef-ficacy of repetitive transcranial magnetic stimulation for hal ucination in patients with schizophrenia spectrum disorders. Experimental intervention was low-frequency repetitive transcranial magnetic stimulation in left temporoparietal cortex for treatment of auditory hal ucination in schizophrenia spectrum disorders. Control groups received sham stimulation. MAIN OUTCOME MEASURES: The primary outcome was total scores of Auditory Hal ucinations Rating Scale, Auditory Hal ucination Subscale of Psychotic Symptom Rating Scale, Positive and Negative Symptom Scale-Auditory Hal ucination item, and Hal ucination Change Scale. Secondary outcomes included response rate, global mental state, adverse effects and cognitive function. RESULTS: Seventeen studies addressing repetitive transcranial magnetic stimulation for treatment of schizophrenia spectrum disorders were screened, with controls receiving sham stimulation. Al data were completely effective, involving 398 patients. Overal mean weighted effect size for repeti-tive transcranial magnetic stimulation versus sham stimulation was statistical y significant (MD =-0.42, 95%CI: -0.64 to -0.20, P = 0.000 2). Patients receiving repetitive transcranial magnetic stimulation responded more frequently than sham stimulation (OR = 2.94, 95%CI: 1.39 to 6.24, P =0.005). No significant differences were found

  10. Risk analysis in oil spill response planning

    International Nuclear Information System (INIS)

    Chernoplekov, A.N.; Alexandrov, A.A.

    2005-01-01

    Tiered response is a basic approach to emergency plans, including oil spill response (OSR). This paper delineates a huge set of accidental scenarios within a certain tier of response generated by a computer during risk assessment. Parameters such as the amount of oil spilled, duration of discharge and types of losses should be provided in OSR scenarios. Examples of applications include offshore installations, sub sea or onshore pipelines, and localized onshore facilities. The paper demonstrates how to use risk analysis results for delineating all likely spills into groups that need a specific tier response. The best world practices and Russian regulatory approaches were outlined and compared. Corresponding algorithms were developed and their application in pipelines was presented. The algorithm combines expert's skills and spill trajectory modeling with the net environmental benefit analysis principle into the incident specific emergency response planning. 9 refs., 13 tabs., 2 figs

  11. Textbooks for Responsible Data Analysis in Excel

    Science.gov (United States)

    Garrett, Nathan

    2015-01-01

    With 27 million users, Excel (Microsoft Corporation, Seattle, WA) is the most common business data analysis software. However, audits show that almost all complex spreadsheets have errors. The author examined textbooks to understand why responsible data analysis is taught. A purposeful sample of 10 textbooks was coded, and then compared against…

  12. Dose-response analysis using R

    DEFF Research Database (Denmark)

    Ritz, Christian; Baty, Florent; Streibig, Jens Carl

    2015-01-01

    Dose-response analysis can be carried out using multi-purpose commercial statistical software, but except for a few special cases the analysis easily becomes cumbersome as relevant, non-standard output requires manual programming. The extension package drc for the statistical environment R provides...

  13. TPASS: a gamma-ray spectrum analysis and isotope identification computer code

    International Nuclear Information System (INIS)

    Dickens, J.K.

    1981-03-01

    The gamma-ray spectral data-reduction and analysis computer code TPASS is described. This computer code is used to analyze complex Ge(Li) gamma-ray spectra to obtain peak areas corrected for detector efficiencies, from which are determined gamma-ray yields. These yields are compared with an isotope gamma-ray data file to determine the contributions to the observed spectrum from decay of specific radionuclides. A complete FORTRAN listing of the code and a complex test case are given

  14. The theoretical study of full spectrum analysis method for airborne gamma-ray spectrometric data

    International Nuclear Information System (INIS)

    Ni Weichong

    2011-01-01

    Spectra of airborne gamma-ray spectrometry was found to be the synthesis of spectral components of radioelement sources by analyzing the constitution of radioactive sources for airborne gamma-ray spectrometric survey and establishing the models of gamma-ray measurement. The mathematical equation for analysising airborne gamma-ray full spectrometric data can be expressed into matrix and related expansions were developed for the mineral resources exploration, environmental radiation measurement, nuclear emergency monitoring, and so on. Theoretical study showed that the atmospheric radon could be directly computed by airborne gamma-ray spectrometric data with full spectrum analysis without the use of the accessional upward-looking detectors. (authors)

  15. Analysis of Hair Trace Elements in Children with Autism Spectrum Disorders and Communication Disorders.

    Science.gov (United States)

    Skalny, Anatoly V; Simashkova, Natalia V; Klyushnik, Tatiana P; Grabeklis, Andrei R; Radysh, Ivan V; Skalnaya, Margarita G; Tinkov, Alexey A

    2017-06-01

    The primary objective of the present study is analysis of hair trace elements content in children with communication disorder (CD) and autism spectrum disorder (ASD). A total of 99 children from control, CD, and ASD groups (n = 33) were examined. All children were additionally divided into two subgroups according to age. Hair levels of trace elements were assessed using inductively coupled plasma mass spectrometry. The difference was considered significant at p elements including the toxic ones, it can be proposed that children suffering from ASD are characterized by more profound alteration of metal handling and excretion in comparison to CD.

  16. Analysis of urinary stone based on a spectrum absorption FTIR-ATR

    International Nuclear Information System (INIS)

    Asyana, V; Haryanto, F; Fitri, L A; Ridwan, T; Anwary, F; Soekersi, H

    2016-01-01

    This research analysed the urinary stone by measuring samples using Fourier transform infrared-attenuated total reflection spectroscopy and black box analysis. The main objective of this study is to find kinds of urinary stone and determine a total spectrum, which is a simple model of the chemical and mineral composition urinary stone through black box analysis using convolution method. The measurements result showed that kinds of urinary stone were pure calcium oxalate monohydrate, ion amino acid calcium oxalate monohydrate, a mixture of calcium oxalate monohydrate with calcium phosphate, a mixture of ion amino acid calcium oxalate monohydrate and calcium phosphate,pure uric acid, ion amino acid uric acid, and a mixture of calcium oxalate monohydrate with ion amino acid uric acid. The results of analysis of black box showed characteristics as the most accurate and precise to confirm the type of urinary stones based on theregion absorption peak on a graph, the results of the convolution, and the shape of the total spectrum on each urinary stones. (paper)

  17. Analysis Spectrum of ECG Signal and QRS Detection during Running on Treadmill

    Science.gov (United States)

    Agung Suhendra, M.; Ilham R., M.; Simbolon, Artha I.; Faizal A., M.; Munandar, A.

    2018-03-01

    The heart is an important organ in our metabolism in which it controls circulatory and oxygen. The heart exercise is needed one of them using the treadmill to prevent health. To analysis, it using electrocardiograph (ECG) to investigating and diagnosing anomalies of the heart. In this paper, we would like to analysis ECG signals during running on the treadmill with kinds of speeds. There are two analysis ECG signals i.e. QRS detection and power spectrum density (PSD). The result of PSD showed that subject 3 has highly for all subject and the result of QRS detection using pan Tomkins algorithm that a percentage of failed detection is an approaching to 0 % for all subject.

  18. Computer code MLCOSP for multiple-correlation and spectrum analysis with a hybrid computer

    International Nuclear Information System (INIS)

    Oguma, Ritsuo; Fujii, Yoshio; Usui, Hozumi; Watanabe, Koichi

    1975-10-01

    Usage of the computer code MLCOSP(Multiple Correlation and Spectrum) developed is described for a hybrid computer installed in JAERI Functions of the hybrid computer and its terminal devices are utilized ingeniously in the code to reduce complexity of the data handling which occurrs in analysis of the multivariable experimental data and to perform the analysis in perspective. Features of the code are as follows; Experimental data can be fed to the digital computer through the analog part of the hybrid computer by connecting with a data recorder. The computed results are displayed in figures, and hardcopies are taken when necessary. Series-messages to the code are shown on the terminal, so man-machine communication is possible. And further the data can be put in through a keyboard, so case study according to the results of analysis is possible. (auth.)

  19. Analysis of the intergranular fracture surface by the Fourier spectrum method

    Energy Technology Data Exchange (ETDEWEB)

    Hao Yao; Tian Jifeng; Wang Zhongguang (National Lab. for Fatigue and Fracture of Materials, Inst. of Metal Research, Academia Sinica, Shen Yang (China))

    1991-11-30

    A quantitative analysis of the fracture surface of a 1045 steel was undertaken in order to relate important microstructural features to brittle intergranular fractures in the steel. It was found that the character of the profile was not random but periodic. There is a direct correspondence between the Fourier spectrum of the profile and the microstructure features. Utilization of secondary-electron line scanning facilitated the analysis of the fracture surface in this case. The results of the analysis from both the profile and the scanning line showed that the first autocorrelation length is related to the average grain size and that the total power corresponds to the impact energy of the fracture. (orig.).

  20. USING THE METHODS OF WAVELET ANALYSIS AND SINGULAR SPECTRUM ANALYSIS IN THE STUDY OF RADIO SOURCE BL LAC

    OpenAIRE

    Donskykh, G. I.; Ryabov, M. I.; Sukharev, A. I.; Aller, M.

    2014-01-01

    We investigated the monitoring data of extragalactic source BL Lac. This monitoring was held withUniversityofMichigan26-meter radio  telescope. To study flux density of extragalactic source BL Lac at frequencies of 14.5, 8 and 4.8 GHz, the wavelet analysis and singular spectrum analysis were used. Calculating the integral wavelet spectra allowed revealing long-term  components  (~7-8 years) and short-term components (~ 1-4 years) in BL Lac. Studying of VLBI radio maps (by the program Mojave) ...

  1. Tapering the sky response for angular power spectrum estimation from low-frequency radio-interferometric data.

    Science.gov (United States)

    Choudhuri, Samir; Bharadwaj, Somnath; Roy, Nirupam; Ghosh, Abhik; Ali, Sk Saiyad

    2016-06-11

    It is important to correctly subtract point sources from radio-interferometric data in order to measure the power spectrum of diffuse radiation like the Galactic synchrotron or the Epoch of Reionization 21-cm signal. It is computationally very expensive and challenging to image a very large area and accurately subtract all the point sources from the image. The problem is particularly severe at the sidelobes and the outer parts of the main lobe where the antenna response is highly frequency dependent and the calibration also differs from that of the phase centre. Here, we show that it is possible to overcome this problem by tapering the sky response. Using simulated 150 MHz observations, we demonstrate that it is possible to suppress the contribution due to point sources from the outer parts by using the Tapered Gridded Estimator to measure the angular power spectrum C ℓ of the sky signal. We also show from the simulation that this method can self-consistently compute the noise bias and accurately subtract it to provide an unbiased estimation of C ℓ .

  2. Autonomic and Neuroendocrine Responses to a Psychosocial Stressor in Adults with Autistic Spectrum

    Science.gov (United States)

    Jansen, Lucres M. C.; Gispen-de Wied, Christine C.; Wiegant, Victor M.; Westenberg, Herman G. M.; Lahuis, Bertine E.; van Engeland, Herman

    2006-01-01

    Objective of the study was to replicate in adults our previous findings of decreased heart rate and normal endocrine responses to stress in autistic children and to elucidate the discrepancy between autonomic and endocrine stress responses by including epinephrine, norepinephrine, oxytocin and vasopressin measurements. Ten autistic spectrum…

  3. Different brain responses during empathy in autism spectrum disorders versus conduct disorder and callous-unemotional traits.

    Science.gov (United States)

    Klapwijk, Eduard T; Aghajani, Moji; Colins, Olivier F; Marijnissen, Godfried M; Popma, Arne; van Lang, Natasja D J; van der Wee, Nic J A; Vermeiren, Robert R J M

    2016-06-01

    Deficits in empathy are reported in autism spectrum disorders (ASD) and also underlie antisocial behavior of individuals with conduct disorder and callous-unemotional traits (CD/CU+). Many studies suggest that individuals with ASD are typically impaired in cognitive aspects of empathy, and individuals with CD/CU+ typically in affective aspects. In the current study, we compared the neural correlates of cognitive and affective aspects of empathy between youth with ASD and youth with CD/CU+. Functional magnetic resonance imaging (fMRI) was used to assess boys with ASD (N = 23), boys with CD/CU+ (N = 23), and typically developing (TD) boys (N = 33), aged 15-19 years. Angry and fearful faces were presented and participants were asked to either infer the emotional state from the face (other-task; emotion recognition) or to judge their own emotional response to the face (self-task; emotional resonance). During emotion recognition, boys with ASD showed reduced responses compared to the other groups in the ventromedial prefrontal cortex (vmPFC). During emotional resonance, the CD/CU+ and ASD groups showed reduced amygdala responses compared to the TD controls, boys with ASD showed reduced responses in bilateral hippocampus, and the CD/CU+ boys showed reduced responses in the inferior frontal gyrus (IFG) and anterior insula (AI). Results suggest differential abnormal brain responses associated with specific aspects of empathic functioning in ASD and CD/CU+. Decreased amygdala responses in ASD and CD/CU+ might point to impaired emotion processing in both disorders, whereas reduced vmPFC responses suggest problems in processing cognitive aspects of empathy in ASD. Reduced IFG/AI responses, finally, suggest decreased emotional resonance in CD/CU+. © 2015 Association for Child and Adolescent Mental Health.

  4. The exclusion-inclusion spectrum in state and community response to sex offenders in Anglo-American and European jurisdictions.

    Science.gov (United States)

    Petrunik, Michael; Deutschmann, Linda

    2008-10-01

    Continental European and Anglo-American jurisdictions differ with regard to criminal justice and community responses to sex offenders on an exclusion-inclusion spectrum ranging from community protection measures on one end to therapeutic programs in the middle and restorative justice measures on the other end. In the United States, populist pressure has resulted in a community protection approach exemplified by sex offender registration, community notification, and civil commitment of violent sexual predators. Although the United Kingdom and Canada have followed, albeit more cautiously, the American trend to adopt exclusionist community protection measures, these countries have significant community-based restorative justice initiatives, such as Circles of Support and Accountability. Although sex offender crises have recently occurred in continental Europe, a long-standing tradition of the medicalization of deviance, along with the existence of social structural buffers against the influence of victim-driven populist penal movements, has thus far limited the spread of formal community protection responses.

  5. QUANTITATIVE EEG COMPARATIVE ANALYSIS BETWEEN AUTISM SPECTRUM DISORDER (ASD AND ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD

    Directory of Open Access Journals (Sweden)

    Plamen D. Dimitrov

    2017-01-01

    Full Text Available Background: Autism is a mental developmental disorder, manifested in the early childhood. Attention deficit hyperactivity disorder is another psychiatric condition of the neurodevelopmental type. Both disorders affect information processing in the nervous system, altering the mechanisms which control how neurons and their synapses are connected and organized. Purpose: To examine if quantitative EEG assessment is sensitive and simple enough to differentiate autism from attention deficit hyperactivity disorder and neurologically typical children. Material and methods: Quantitative EEG is a type of electrophysiological assessment that uses computerized mathematical analysis to convert the raw waveform data into different frequency ranges. Each frequency range is averaged across a sample of data and quantified into mean amplitude (voltage in microvolts mV. We performed quantitative EEG analysis and compared 4 cohorts of children (aged from 3 to 7 years: with autism (high [n=27] and low [n=52] functioning, with attention deficit hyperactivity disorder [n=34], and with typical behavior [n75]. Results: Our preliminary results show that there are significant qEEG differences between the groups of patients and the control cohort. The changes affect the potential levels of delta-, theta-, alpha-, and beta- frequency spectrums. Conclusion: The present study shows some significant quantitative EEG findings in autistic patients. This is a step forward in our efforts, aimed at defining specific neurophysiologic changes, in order to develop and refine strategies for early diagnosis of autism spectrum disorders, differentiation from other development conditions in childhood, detection of specific biomarkers and early initiation of treatment.

  6. Randomised multichannel singular spectrum analysis of the 20th century climate data

    Directory of Open Access Journals (Sweden)

    Teija Seitola

    2015-12-01

    Full Text Available In this article, we introduce a new algorithm called randomised multichannel singular spectrum analysis (RMSSA, which is a generalisation of the traditional multichannel singular spectrum analysis (MSSA into problems of arbitrarily large dimension. RMSSA consists of (1 a dimension reduction of the original data via random projections, (2 the standard MSSA step and (3 a recovery of the MSSA eigenmodes from the reduced space back to the original space. The RMSSA algorithm is presented in detail and additionally we show how to integrate it with a significance test based on a red noise null-hypothesis by Monte-Carlo simulation. Finally, RMSSA is applied to decompose the 20th century global monthly mean near-surface temperature variability into its low-frequency components. The decomposition of a reanalysis data set and two climate model simulations reveals, for instance, that the 2–6 yr variability centred in the Pacific Ocean is captured by all the data sets with some differences in statistical significance and spatial patterns.

  7. Dynamics Evolution Investigation of Mack Mode Instability in a Hypersonic Boundary Layer by Bicoherence Spectrum Analysis

    Science.gov (United States)

    Han, Jian; Jiang, Nan

    2012-07-01

    The instability of a hypersonic boundary layer on a cone is investigated by bicoherence spectrum analysis. The experiment is conducted at Mach number 6 in a hypersonic wind tunnel. The time series signals of instantaneous fluctuating surface-thermal-flux are measured by Pt-thin-film thermocouple temperature sensors mounted at 28 stations on the cone surface along streamwise direction to investigate the development of the unstable disturbances. The bicoherence spectrum analysis based on wavelet transform is employed to investigate the nonlinear interactions of the instability of Mack modes in hypersonic laminar boundary layer transition. The results show that wavelet bicoherence is a powerful tool in studying the unstable mode nonlinear interaction of hypersonic laminar-turbulent transition. The first mode instability gives rise to frequency shifts to higher unstable modes at the early stage of hypersonic laminar-turbulent transition. The modulations subsequently lead to the second mode instability occurrence. The second mode instability governs the last stage of instability and final breakdown to turbulence with multi-scale disturbances growth.

  8. Dynamics Evolution Investigation of Mack Mode Instability in a Hypersonic Boundary Layer by Bicoherence Spectrum Analysis

    International Nuclear Information System (INIS)

    Han Jian; Jiang Nan

    2012-01-01

    The instability of a hypersonic boundary layer on a cone is investigated by bicoherence spectrum analysis. The experiment is conducted at Mach number 6 in a hypersonic wind tunnel. The time series signals of instantaneous fluctuating surface-thermal-flux are measured by Pt-thin-film thermocouple temperature sensors mounted at 28 stations on the cone surface along streamwise direction to investigate the development of the unstable disturbances. The bicoherence spectrum analysis based on wavelet transform is employed to investigate the nonlinear interactions of the instability of Mack modes in hypersonic laminar boundary layer transition. The results show that wavelet bicoherence is a powerful tool in studying the unstable mode nonlinear interaction of hypersonic laminar-turbulent transition. The first mode instability gives rise to frequency shifts to higher unstable modes at the early stage of hypersonic laminar-turbulent transition. The modulations subsequently lead to the second mode instability occurrence. The second mode instability governs the last stage of instability and final breakdown to turbulence with multi-scale disturbances growth. (fundamental areas of phenomenology(including applications))

  9. A study on hybrid split-spectrum processing technique for enhanced reliability in ultrasonic signal analysis

    International Nuclear Information System (INIS)

    Huh, Hyung; Koo, Kil Mo; Cheong, Yong Moo; Kim, G. J.

    1995-01-01

    Many signal-processing techniques have been found to be useful in ultrasonic and nondestructive evaluation. Among the most popular techniques are signal averaging, spatial compounding, matched filters, and homomorphic processing. One of the significant new process is split-spectrum processing(SSP), which can be equally useful in signal-to-noise ratio(SNR) improvement and grain characterization in several engineering materials. The purpose of this paper is to explore the utility of SSP in ultrasonic NDE. A wide variety of engineering problems are reviewed and suggestions for implementation of the technique are provided. SSP uses the frequency-dependent response of the interfering coherent noise produced by unresolvable scatters in the resolution range cell of a transducer. It is implemented by splitting the Sequency spectrum of the received signal by using Gaussian bandpass filters. The theoretical basis for the potential of SSP for grain characterization in SUS 304 material is discussed, and some experimental-evidence for the feasibility of the approach is presented. Results of SNR enhancement in signals obtained from real four samples of SUS 304. The influence of various processing parameters on the performance of the processing technique is also discussed. The minimization algorithm. which provides an excellent SNR enhancement when used either in conjunction with other SSP algorithms like polarity-check or by itself, is also presented.

  10. A Study on Hybrid Split-Spectrum Processing Technique for Enhanced Reliability in Ultrasonic Signal Analysis

    International Nuclear Information System (INIS)

    Huh, H.; Koo, K. M.; Kim, G. J.

    1996-01-01

    Many signal-processing techniques have been found to be useful in ultrasonic and nondestructive evaluation. Among the most popular techniques are signal averaging, spatial compounding, matched filters and homomorphic processing. One of the significant new process is split-spectrum processing(SSP), which can be equally useful in signal-to-noise ratio(SNR) improvement and grain characterization in several specimens. The purpose of this paper is to explore the utility of SSP in ultrasonic NDE. A wide variety of engineering problems are reviewed, and suggestions for implementation of the technique are provided. SSP uses the frequency-dependent response of the interfering coherent noise produced by unresolvable scatters in the resolution range cell of a transducer. It is implemented by splitting the frequency spectrum of the received signal by using gaussian bandpass filter. The theoretical basis for the potential of SSP for grain characterization in SUS 304 material is discussed, and some experimental evidence for the feasibility of the approach is presented. Results of SNR enhancement in signals obtained from real four samples of SUS 304. The influence of various processing parameters on the performance of the processing technique is also discussed. The minimization algorithm, which provides an excellent SNR enhancement when used either in conjunction with other SSP algorithms like polarity-check or by itself, is also presented

  11. Transient Safety Analysis of Fast Spectrum TRU Burning LWRs with Internal Blankets

    Energy Technology Data Exchange (ETDEWEB)

    Downar, Thomas [Univ. of Michigan, Ann Arbor, MI (United States); Zazimi, Mujid [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Hill, Bob [Argonne National Lab. (ANL), Argonne, IL (United States)

    2015-01-31

    The objective of this proposal was to perform a detailed transient safety analysis of the Resource-Renewable BWR (RBWR) core designs using the U.S. NRC TRACE/PARCS code system. This project involved the same joint team that has performed the RBWR design evaluation for EPRI and therefore be able to leverage that previous work. And because of their extensive experience with fast spectrum reactors and parfait core designs, ANL was also part the project team. The principal outcome of this project was the development of a state-of-the-art transient analysis capability for GEN-IV reactors based on Monte Carlo generated cross sections and the US NRC coupled code system TRACE/PARCS, and a state-of-the-art coupled code assessment of the transient safety performance of the RBWR.

  12. Comparison of least-squares vs. maximum likelihood estimation for standard spectrum technique of β−γ coincidence spectrum analysis

    International Nuclear Information System (INIS)

    Lowrey, Justin D.; Biegalski, Steven R.F.

    2012-01-01

    The spectrum deconvolution analysis tool (SDAT) software code was written and tested at The University of Texas at Austin utilizing the standard spectrum technique to determine activity levels of Xe-131m, Xe-133m, Xe-133, and Xe-135 in β–γ coincidence spectra. SDAT was originally written to utilize the method of least-squares to calculate the activity of each radionuclide component in the spectrum. Recently, maximum likelihood estimation was also incorporated into the SDAT tool. This is a robust statistical technique to determine the parameters that maximize the Poisson distribution likelihood function of the sample data. In this case it is used to parameterize the activity level of each of the radioxenon components in the spectra. A new test dataset was constructed utilizing Xe-131m placed on a Xe-133 background to compare the robustness of the least-squares and maximum likelihood estimation methods for low counting statistics data. The Xe-131m spectra were collected independently from the Xe-133 spectra and added to generate the spectra in the test dataset. The true independent counts of Xe-131m and Xe-133 are known, as they were calculated before the spectra were added together. Spectra with both high and low counting statistics are analyzed. Studies are also performed by analyzing only the 30 keV X-ray region of the β–γ coincidence spectra. Results show that maximum likelihood estimation slightly outperforms least-squares for low counting statistics data.

  13. Revision and extension to the analysis of the third spectrum of bromine: Br III

    Science.gov (United States)

    Jabeen, S.; Tauheed, A.

    2015-03-01

    The spectrum of doubly ionized bromine (Br III) has been investigated in the vacuum ultraviolet wavelength region. Br2+ is an As-like ion with ground configuration of 4s24p3, thus a 3-electron system possessing a complex structure. The theoretical prediction was made using Cowan's quasi-relativistic Hartree-Fock code with superposition of configurations involving the 4s4p4, 4s24p2 (4d+5d+6d+5s+6s+7s), 4s4p3 (5p+4f), 4p4(4d+5s), 4s24p5s5p, 4s4p2 (4d2+5s2), 4s4p24f2 configurations for the even parity matrix and the 4s24p3, 4s24p2 (5p+6p+4f+5f) configurations for the odd parity matrix. Several previously reported levels of Br III have been revised, and new configurations have been added to the analysis. The spectrum used for this work was recorded on a 3-m normal incidence spectrograph in the wavelength region of 400-1326 Å using a triggered vacuum spark source. One hundred and two energy levels belonging to the 4s24p3, 4s4p4, 4s24p2 (4d+5d+6d+5s+6s +7s) configurations have been established, eighty-six being new. Two hundred and seventy-eight lines have been identified in this spectrum. The accuracy of our wavelength measurements for sharp and unblended lines is ±0.006 Å. The ionization potential of Br III was found to be 281,250±100 cm-1 (34.870±0.012 eV).

  14. Revision and extension to the analysis of the third spectrum of tellurium: Te III

    International Nuclear Information System (INIS)

    Tauheed, A.; Naz, A.

    2011-01-01

    The spectrum of doubly ionized tellurium atom (Te III) has been investigated in the vacuum ultraviolet wavelength region. The ground configuration of Te III is 5s 2 5p 2 and the excited configurations are of the type 5s 2 5p nl. The core excitation leads to a 5s5p 3 configuration. Cowan's multi-configuration interaction code was utilized to predict the ion structure. The observed spectrum of tellurium was recorded on a 3-m normal incidence vacuum spectrograph of Antigonish Laboratory (Canada) in the wavelength region of 300 - 2000 A by using a triggered spark light source for the excitation of the spectrum. The 5s 2 5p 2 - [ 5s 2 5p (5d + 6d + 7d + 6s + 7s + 8s) + 5s5p 3 ] transition array has been analyzed. Previously reported levels by Joshi et al have been confirmed while the older analysis by Crooker and Joshi has been revised and extended to include the 5s 2 5p (5d, 6d, 7d, 6s,7s, 8s) and 5s5p 3 configurations. Least-squares- fitted parametric calculations were used to interpret the final results. One hundred and fifty spectral lines have been identified to establish 60 energy levels. Our wavelength accuracy for unblended and sharp lines is better than ±0.005 A. The ionization potential of Te III was found to be 224550 ± 300 cm -1 (27.841 ± 0.037eV).

  15. [Analysis of the character of film decomposition of methyl methacrylate (MMA) coated urea by infrared spectrum].

    Science.gov (United States)

    Li, Dong-po; Wu, Zhi-jie; Liang, Cheng-hua; Chen, Li-jun; Zhang, Yu-lan; Nie, Yan-xi

    2012-03-01

    The degradability characteristics of film with 4 kinds of methyl methacrylate coated urea amended with inhibitors were analyzed by FITR, which was purposed to supply theoretical basis for applying the FITR analysis method to film decomposition and methyl methacrylate coated urea fertilizers on farming. The result showed that the chemical component, molecule structure and material form of the membrane were not changed because of adding different inhibitors to urea. the main peaks of expressing film degradation process were brought by the -C-H of CH3 & CH2, -OH, C-O, C-C, C-O-C, C=O, C=C flexing vibrancy in asymmetry and symmetry in 3 479-3 195, 2 993--2 873, 1 741-1 564, 1 461-925 and 850-650 cm(-1). The peak value changed from smooth to tip, and from width to narrow caused by chemical structural transform of film The infrared spectrum of 4 kinds of fertilizers was not different remarkably before 60 days, and the film was slowly degraded. But degradation of the film was expedited after 60 days, it was most quickened at 120 day, and the decomposition rate of film was decreased at 310 day. The substantiality change of film in main molecule structure of 4 kinds of fertilizers didn't happen in 310 days. The main component of film materials was degraded most slowly in brown soil. The speed of film degradation wasn't heavily impacted by different inhibitors. The characteristic of film degradation may be monitored entirely by infrared spectrum. The degradation dynamic, chemical structure change, degradation speed difference of the film could be represented through infrared spectrum.

  16. Extracting sensitive spectrum bands of rapeseed using multiscale multifractal detrended fluctuation analysis

    Science.gov (United States)

    Jiang, Shan; Wang, Fang; Shen, Luming; Liao, Guiping; Wang, Lin

    2017-03-01

    Spectrum technology has been widely used in crop non-destructive testing diagnosis for crop information acquisition. Since spectrum covers a wide range of bands, it is of critical importance to extract the sensitive bands. In this paper, we propose a methodology to extract the sensitive spectrum bands of rapeseed using multiscale multifractal detrended fluctuation analysis. Our obtained sensitive bands are relatively robust in the range of 534 nm-574 nm. Further, by using the multifractal parameter (Hurst exponent) of the extracted sensitive bands, we propose a prediction model to forecast the Soil and plant analyzer development values ((SPAD), often used as a parameter to indicate the chlorophyll content) and an identification model to distinguish the different planting patterns. Three vegetation indices (VIs) based on previous work are used for comparison. Three evaluation indicators, namely, the root mean square error, the correlation coefficient, and the relative error employed in the SPAD values prediction model all demonstrate that our Hurst exponent has the best performance. Four rapeseed compound planting factors, namely, seeding method, planting density, fertilizer type, and weed control method are considered in the identification model. The Youden indices calculated by the random decision forest method and the K-nearest neighbor method show that our Hurst exponent is superior to other three Vis, and their combination for the factor of seeding method. In addition, there is no significant difference among the five features for other three planting factors. This interesting finding suggests that the transplanting and the direct seeding would make a big difference in the growth of rapeseed.

  17. Meta-Analysis of Studies Incorporating the Interests of Young Children with Autism Spectrum Disorders into Early Intervention Practices

    OpenAIRE

    Dunst, Carl J.; Trivette, Carol M.; Hamby, Deborah W.

    2012-01-01

    Incorporating the interests and preferences of young children with autism spectrum disorders into interventions to promote prosocial behavior and decrease behavior excesses has emerged as a promising practice for addressing the core features of autism. The efficacy of interest-based early intervention practices was examined in a meta-analysis of 24 studies including 78 children 2 to 6 years of age diagnosed with autism spectrum disorders. Effect size analyses of intervention versus noninterve...

  18. Heterogeneity of response to antipsychotics from multiple disorders in the schizophrenia spectrum.

    Science.gov (United States)

    Garver, D L; Holcomb, J A; Christensen, J D

    2000-12-01

    Antipsychotic response after the initiation of neuroleptic treatment shows wide variation in schizophrenic patient populations. In this overview, the authors suggest that the variance in antipsychotic drug response within schizophrenia can be reduced by resolving the schizophrenias into several discrete "endophenotypes," each with different etiologic underpinnings. Studies relating differences in the relative speed or completeness of antipsychotic response to differences in distribution of 2 biological markers with possible etiologic significance are reviewed. Such studies had assessed recently hospitalized, neuroleptic-free patients undergoing exacerbation of nonaffective psychotic disorders. Prior to initiation of neuroleptic, the cohort of patients had been assessed for the quantity of the dopamine metabolite homovanillic acid in plasma (pHVA) and had undergone the first of 2 magnetic resonance imaging (MRI) studies for analyses of ventricle volumes. A second MRI was subsequently performed during a period of (partial) remission to determine within-patient stability of ventricular volumes. These selected studies assessed the distribution of pHVA and distribution of rates of ventricular change, with non-normal distributions resolved by K-means clustering. The speed and completeness of neuroleptic-induced antipsychotic response were related to 3 clusters of patients delineated by modal distributions of pHVA and of apparent rates of ventricular change. At least 3 unique "endophenotypes" of the "group of the schizophrenias" can be defined with respect to speed and completeness of antipsychotic response. Each endophenotype appears to show at least one unique biological feature that differentiates it from a normal comparison group. A rapidly responsive psychosis was associated with excessive production of dopamine, as identifiable by elevation of pHVA and a "good-prognosis" course. A delayed-response psychosis had low-to-normal pHVA, clinically demonstrated persistent

  19. Bayesian statistics applied to neutron activation data for reactor flux spectrum analysis

    International Nuclear Information System (INIS)

    Chiesa, Davide; Previtali, Ezio; Sisti, Monica

    2014-01-01

    Highlights: • Bayesian statistics to analyze the neutron flux spectrum from activation data. • Rigorous statistical approach for accurate evaluation of the neutron flux groups. • Cross section and activation data uncertainties included for the problem solution. • Flexible methodology applied to analyze different nuclear reactor flux spectra. • The results are in good agreement with the MCNP simulations of neutron fluxes. - Abstract: In this paper, we present a statistical method, based on Bayesian statistics, to analyze the neutron flux spectrum from the activation data of different isotopes. The experimental data were acquired during a neutron activation experiment performed at the TRIGA Mark II reactor of Pavia University (Italy) in four irradiation positions characterized by different neutron spectra. In order to evaluate the neutron flux spectrum, subdivided in energy groups, a system of linear equations, containing the group effective cross sections and the activation rate data, has to be solved. However, since the system’s coefficients are experimental data affected by uncertainties, a rigorous statistical approach is fundamental for an accurate evaluation of the neutron flux groups. For this purpose, we applied the Bayesian statistical analysis, that allows to include the uncertainties of the coefficients and the a priori information about the neutron flux. A program for the analysis of Bayesian hierarchical models, based on Markov Chain Monte Carlo (MCMC) simulations, was used to define the problem statistical model and solve it. The first analysis involved the determination of the thermal, resonance-intermediate and fast flux components and the dependence of the results on the Prior distribution choice was investigated to confirm the reliability of the Bayesian analysis. After that, the main resonances of the activation cross sections were analyzed to implement multi-group models with finer energy subdivisions that would allow to determine the

  20. Analysis of neutron spectrum effects on primary damage in tritium breeding blankets

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Yong Hee, E-mail: cyh871@snu.ac.kr [School of Energy Systems Engineering, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul 151-744 (Korea, Republic of); Joo, Han Gyu [School of Energy Systems Engineering, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul 151-744 (Korea, Republic of)

    2012-07-15

    The effect of neutron spectrum on primary damages in a structural material of a tritium breeding blanket is investigated with a newly established recoil spectrum estimation system. First, a recoil spectrum generation code is developed to obtain the energy spectrum of primary knock-on atoms (PKAs) for a given neutron spectrum utilizing the latest ENDF/B data. Secondly, a method for approximating the high energy tail of the recoil spectrum is introduced to avoid expensive molecular dynamics calculations for high energy PKAs using the concept of recoil energy of the secondary knock-on atoms originated by the INtegration of CAScades (INCAS) model. Thirdly, the modified spectrum is combined with a set of molecular dynamics calculation results to estimate the primary damage parameters such as the number of surviving point defects. Finally, the neutron spectrum is varied by changing the material of the spectral shifter and the result in primary damage parameters is examined.

  1. Analysis of neutron spectrum effects on primary damage in tritium breeding blankets

    Science.gov (United States)

    Choi, Yong Hee; Joo, Han Gyu

    2012-07-01

    The effect of neutron spectrum on primary damages in a structural material of a tritium breeding blanket is investigated with a newly established recoil spectrum estimation system. First, a recoil spectrum generation code is developed to obtain the energy spectrum of primary knock-on atoms (PKAs) for a given neutron spectrum utilizing the latest ENDF/B data. Secondly, a method for approximating the high energy tail of the recoil spectrum is introduced to avoid expensive molecular dynamics calculations for high energy PKAs using the concept of recoil energy of the secondary knock-on atoms originated by the INtegration of CAScades (INCAS) model. Thirdly, the modified spectrum is combined with a set of molecular dynamics calculation results to estimate the primary damage parameters such as the number of surviving point defects. Finally, the neutron spectrum is varied by changing the material of the spectral shifter and the result in primary damage parameters is examined.

  2. The method in γ spectrum analysis with artificial neural network based on MATLAB

    International Nuclear Information System (INIS)

    Bai Lixin; Zhang Yiyun; Xu Jiayun; Wu Liping

    2003-01-01

    Analyzing γ spectrum with artificial neural network have the advantage of using the information of whole spectrum and having high analyzing precision. A convenient realization based on MATLAB was present in this

  3. Analysis of the material configurations and influence on the dynamic response

    Directory of Open Access Journals (Sweden)

    Murčinková Zuzana

    2018-01-01

    Full Text Available The paper presents the analysis of the material configuration of composites based on the measurement of their dynamic response. The article presents the measurement scheme, the design of the measuring stand together with the analysis of the results. Moreover, it analyses the FFT spectrums of layered long fibre composite, short fibre composites of different fibres materials and homogeneous materials as steel and aluminium alloy.

  4. Revision and extension to the analysis of the third spectrum of bromine: Br III

    International Nuclear Information System (INIS)

    Jabeen, S.; Tauheed, A.

    2015-01-01

    The spectrum of doubly ionized bromine (Br III) has been investigated in the vacuum ultraviolet wavelength region. Br 2+ is an As-like ion with ground configuration of 4s 2 4p 3 , thus a 3-electron system possessing a complex structure. The theoretical prediction was made using Cowan's quasi-relativistic Hartree–Fock code with superposition of configurations involving the 4s4p 4 , 4s 2 4p 2 (4d+5d+6d+5s+6s+7s), 4s4p 3 (5p+4f), 4p 4 (4d+5s), 4s 2 4p5s5p, 4s4p 2 (4d 2 +5s 2 ), 4s4p 2 4f 2 configurations for the even parity matrix and the 4s 2 4p 3 , 4s 2 4p 2 (5p+6p+4f+5f) configurations for the odd parity matrix. Several previously reported levels of Br III have been revised, and new configurations have been added to the analysis. The spectrum used for this work was recorded on a 3-m normal incidence spectrograph in the wavelength region of 400–1326 Å using a triggered vacuum spark source. One hundred and two energy levels belonging to the 4s 2 4p 3 , 4s4p 4 , 4s 2 4p 2 (4d+5d+6d+5s+6s +7s) configurations have been established, eighty-six being new. Two hundred and seventy-eight lines have been identified in this spectrum. The accuracy of our wavelength measurements for sharp and unblended lines is ±0.006 Å. The ionization potential of Br III was found to be 281,250±100 cm −1 (34.870±0.012 eV). - Highlights: • The spectrum of Br was recorded on a 3-m grating spectrograph with a triggered spark source. • Most of the known energy levels have been revised and further new configurations have been added. • Superposition-of-configurations calculations with relativistic corrections were made for theoretical predictions. • Radiative weighted oscillator strength (gf) & radiative transition probabilities (gA) were calculated. • Ionization Potential of Br III was determined experimentally

  5. Spectrum library concept and pulse shape analysis in liquid scintillation counting

    Energy Technology Data Exchange (ETDEWEB)

    Kaihola, L [Wallac Oy, Turku (Finland)

    1997-03-01

    Wallac introduced in 1990 a new absolute liquid scintillation counting (LSC) method, Digital Overlay Technique (DOT) to correct for quench. This method allows quantization of multilabel samples by referring to library spectra which are generated against chemical and color quench indices at the factory. The libraries can further be expanded to any beta emitter by user with a method called fine tuning, which can be carried out even with a single sample. Spectrum libraries are created over the whole spectrum range of the radionuclide and allow automatic identification of a single label beta emitting radionuclide, called Easy Count method. Another improvement in LSC is commercial introduction of Pulse Shape Analysis (PSA) in 1986 by Wallac. This method recognizes alpha particle decay by pulse shape and leads to excellent sensitivity in alpha counting because most of the background signal in LSC comprises of short or beta like pulses. PSA detects alpha events in the presence of high excess of beta activity over alphas, up to a ratio 100000 to 1. (orig.)

  6. Design and Analysis of Hybrid Solar Lighting and Full-Spectrum Solar Energy Systems

    International Nuclear Information System (INIS)

    Muhs, J.D.

    2001-01-01

    This paper describes a systems-level design and analysis of a new approach for improving the energy efficiency and affordability of solar energy in buildings, namely, hybrid solar lighting and full-spectrum solar energy systems. By using different portions of the solar spectrum simultaneously for multiple end-use applications in buildings, the proposed system offers unique advantages over other alternatives for using sunlight to displace electricity (conventional topside daylighting and solar technologies). Our preliminary work indicates that hybrid solar lighting, a method of collecting and distributing direct sunlight for lighting purposes, will alleviate many of the problems with passive daylighting systems of today, such as spatial and temporal variability, glare, excess illumination, cost, and energy efficiency. Similarly, our work suggests that the most appropriate use of the visible portion of direct, nondiffuse sunlight from an energy-savings perspective is to displace electric light rather than generate electricity. Early estimates detailed in this paper suggest an anticipated system cost of well under$2.0/Wp and 5-11(cents)/kWh for displaced and generated electricity in single-story commercial building applications. Based on a number of factors discussed in the paper, including sunlight availability, building use scenarios, time-of-day electric utility rates, cost, and efficacy of the displaced electric lights, the simple payback of this approach in many applications could eventually be well under 5 years

  7. Performance analysis of switch-based multiuser scheduling schemes with adaptive modulation in spectrum sharing systems

    KAUST Repository

    Qaraqe, Marwa

    2014-04-01

    This paper focuses on the development of multiuser access schemes for spectrum sharing systems whereby secondary users are allowed to share the spectrum with primary users under the condition that the interference observed at the primary receiver is below a predetermined threshold. In particular, two scheduling schemes are proposed for selecting a user among those that satisfy the interference constraint and achieve an acceptable signal-to-noise ratio level. The first scheme focuses on optimizing the average spectral efficiency by selecting the user that reports the best channel quality. In order to alleviate the relatively high feedback required by the first scheme, a second scheme based on the concept of switched diversity is proposed, where the base station (BS) scans the secondary users in a sequential manner until a user whose channel quality is above an acceptable predetermined threshold is found. We develop expressions for the statistics of the signal-to-interference and noise ratio as well as the average spectral efficiency, average feedback load, and the delay at the secondary BS. We then present numerical results for the effect of the number of users and the interference constraint on the optimal switching threshold and the system performance and show that our analysis results are in perfect agreement with the numerical results. © 2014 John Wiley & Sons, Ltd.

  8. Adolescent Boys with an Autism Spectrum Disorder and Their Experience of Sexuality: An Interpretative Phenomenological Analysis

    Science.gov (United States)

    Dewinter, Jeroen; Van Parys, Hanna; Vermeiren, Robert; van Nieuwenhuizen, Chijs

    2017-01-01

    This qualitative study explored how adolescent boys with autism spectrum disorder experience their sexuality. Previous research has demonstrated that sexuality is a developmental task for boys with autism spectrum disorder, as it is for their peers. Case studies have suggested a relation between autism spectrum disorder and atypical sexual…

  9. Development of a noise reduction program of a prompt gamma spectrum based on principal component analysis for an explosive detection

    International Nuclear Information System (INIS)

    Lee, Yun Hee; Im, Hee Jung; Song, Byung ChoI; Park, Yong Joon; Kim, Won Ho; Cho, Jung Hwan

    2005-01-01

    This work demonstrates a developed program to reduce noises of a prompt gamma-ray spectrum measured by irradiating neutrons into baggage. The noises refer to random variations mainly caused by electrical fluctuations and also by a measurement time. Especially, since the short measurement time yields such a noisy spectrum in which its special peak can not be observed, it is necessary to extract its characteristic signals from the spectrum to identify an explosive hidden in luggage. Principal component analysis(PCA) that is a multivariate statistical technique is closely related to singular value decomposition(SVD). The SVD-based PCA decreases the noise by reconstructing the spectrum after determining the number of principal components corresponding important signals based on the history data that sufficiently describe its population. In this study, we present a visualized program of the above procedure using the MATLAB 7.04 programming language. When our program is started, it requires an arbitrary measured spectrum to be reduced and history spectra as input files. If user selects the files with menu, our program automatically carries out the PCA procedure and provides its noise-reduced spectrum plot as well as the original spectrum plot into an output window. In addition, user can obtain signal-to-noise ratio of an interesting peak by defining the peak and noise ranges with menu

  10. Frequency spectrum method-based stress analysis for oil pipelines in earthquake disaster areas.

    Directory of Open Access Journals (Sweden)

    Xiaonan Wu

    Full Text Available When a long distance oil pipeline crosses an earthquake disaster area, inertial force and strong ground motion can cause the pipeline stress to exceed the failure limit, resulting in bending and deformation failure. To date, researchers have performed limited safety analyses of oil pipelines in earthquake disaster areas that include stress analysis. Therefore, using the spectrum method and theory of one-dimensional beam units, CAESAR II is used to perform a dynamic earthquake analysis for an oil pipeline in the XX earthquake disaster area. This software is used to determine if the displacement and stress of the pipeline meet the standards when subjected to a strong earthquake. After performing the numerical analysis, the primary seismic action axial, longitudinal and horizontal displacement directions and the critical section of the pipeline can be located. Feasible project enhancement suggestions based on the analysis results are proposed. The designer is able to utilize this stress analysis method to perform an ultimate design for an oil pipeline in earthquake disaster areas; therefore, improving the safe operation of the pipeline.

  11. Frequency spectrum method-based stress analysis for oil pipelines in earthquake disaster areas.

    Science.gov (United States)

    Wu, Xiaonan; Lu, Hongfang; Huang, Kun; Wu, Shijuan; Qiao, Weibiao

    2015-01-01

    When a long distance oil pipeline crosses an earthquake disaster area, inertial force and strong ground motion can cause the pipeline stress to exceed the failure limit, resulting in bending and deformation failure. To date, researchers have performed limited safety analyses of oil pipelines in earthquake disaster areas that include stress analysis. Therefore, using the spectrum method and theory of one-dimensional beam units, CAESAR II is used to perform a dynamic earthquake analysis for an oil pipeline in the XX earthquake disaster area. This software is used to determine if the displacement and stress of the pipeline meet the standards when subjected to a strong earthquake. After performing the numerical analysis, the primary seismic action axial, longitudinal and horizontal displacement directions and the critical section of the pipeline can be located. Feasible project enhancement suggestions based on the analysis results are proposed. The designer is able to utilize this stress analysis method to perform an ultimate design for an oil pipeline in earthquake disaster areas; therefore, improving the safe operation of the pipeline.

  12. A Meta-Analysis of Maternal Smoking during Pregnancy and Autism Spectrum Disorder Risk in Offspring

    Directory of Open Access Journals (Sweden)

    Shiming Tang

    2015-08-01

    Full Text Available The association between maternal smoking during pregnancy and autism spectrum disorder (ASD risk in offspring has been investigated in several studies, but the evidence is not conclusive. We, therefore, conducted this meta-analysis to explore whether an association exists between maternal smoking during pregnancy and ASD risk in offspring. We searched PubMed, Embase, Web of Science, and the Cochrane Library for studies of maternal smoking during pregnancy and ASD risk in offspring up to 10 June 2015. The random-effects model was used to combine results from individual studies. 15 observational studies (6 cohort studies and 9 case-control studies, with 17,890 ASD cases and 1,810,258 participants were included for analysis. The pooled odds ratio (OR was 1.02 (95% confidence interval (CI: 0.93–1.13 comparing mothers who smoked during pregnancy with those who did not. Subgroup and sensitivity analysis suggested the overall result of this analysis was robust. Results from this meta-analysis indicate that maternal smoking during pregnancy is not associated with ASD risk in offspring. Further well-designed cohort studies are needed to confirm the present findings.

  13. Normal spectrum of pulmonary parametric response map to differentiate lung collapsibility: distribution of densitometric classifications in healthy adult volunteers

    International Nuclear Information System (INIS)

    Silva, Mario; Nemec, Stefan F.; Dufresne, Valerie; Occhipinti, Mariaelena; Heidinger, Benedikt H.; Bankier, Alexander A.; Chamberlain, Ryan

    2016-01-01

    Pulmonary parametric response map (PRM) was proposed for quantitative densitometric phenotypization of chronic obstructive pulmonary disease. However, little is known about this technique in healthy subjects. The purpose of this study was to describe the normal spectrum of densitometric classification of pulmonary PRM in a group of healthy adults. 15 healthy volunteers underwent spirometrically monitored chest CT at total lung capacity (TLC) and functional residual capacity (FRC). The paired CT scans were analyzed by PRM for voxel-by-voxel characterization of lung parenchyma according to 4 densitometric classifications: normal lung (TLC ≥ -950 HU, FRC ≥ -856 HU); expiratory low attenuation area (LAA) (TLC ≥ -950 HU, FRC < -856 HU); dual LAA (TLC<-950 HU, FRC < -856 HU); uncharacterized (TLC < -950 HU, FRC ≥ -856 HU). PRM spectrum was 78 % ± 10 % normal lung, 20 % ± 8 % expiratory LAA, and 1 % ± 1 % dual LAA. PRM was similar between genders, there was moderate correlation between dual LAA and spirometrically assessed TLC (R = 0.531; p = 0.042), and between expiratory LAA and Vol Exp/Insp ratio (R = -0.572; p = 0.026). PRM reflects the predominance of normal lung parenchyma in a group of healthy volunteers. However, PRM also confirms the presence of physiological expiratory LAA seemingly related to air trapping and a minimal amount of dual LAA likely reflecting emphysema. (orig.)

  14. An emergency response intercomparison exercise using a synthetically generated gamma-ray spectrum

    DEFF Research Database (Denmark)

    Dowdall, M.; Selnæs, O.G.; Standring, W.J.F.

    2010-01-01

    Although high resolution gamma ray spectrometry serves as the primary analytical technique in emergency response situations, chances for laboratories to practice analysing the type of spectra that may be expected in the early phase of such a situation are limited. This problem is more acute for l...

  15. Pivotal Response Treatment for Infants At-Risk for Autism Spectrum Disorders: A Pilot Study

    Science.gov (United States)

    Steiner, Amanda Mossman; Gengoux, Grace W.; Klin, Ami; Chawarska, Katarzyna

    2013-01-01

    Presently there is limited research to suggest efficacious interventions for infants at-risk for autism. Pivotal response treatment (PRT) has empirical support for use with preschool children with autism, but there are no reports in the literature utilizing this approach with infants. In the current study, a developmental adaptation of PRT was…

  16. The Influence of Maternal Language Responsiveness on the Expressive Speech Production of Children with Autism Spectrum Disorders: A Microanalysis of Mother-Child Play Interactions

    Science.gov (United States)

    Walton, Katherine M.; Ingersoll, Brooke R.

    2015-01-01

    Adult responsiveness is related to language development both in young typically developing children and in children with autism spectrum disorders, such that parents who use more responsive language with their children have children who develop better language skills over time. This study used a micro-analytic technique to examine how two facets…

  17. Response to Electroconvulsive Therapy in Patients With Autism Spectrum Disorder and Intractable Challenging Behaviors Associated With Symptoms of Catatonia.

    Science.gov (United States)

    Sajith, Sreedharan Geetha; Liew, Siew Fai; Tor, Phern Chern

    2017-03-01

    There are several reports of electroconvulsive therapy (ECT) used in autism spectrum disorder (ASD) in the context of catatonic symptoms. We describe response to ECT in two adults with ASD and intellectual disability with intractable aggression and self-injurious behaviors associated with catatonic symptoms who had not responded to standard interventions. Unilateral ECT at a frequency of 3 times a week was given followed by weekly maintenance ECT. Patients' catatonic symptoms included episodes of agitation and echophenomena. Electroconvulsive therapy resulted in significant improvement in their behavior problems but 1 patient relapsed when the ECT was discontinued or frequency of treatment reduced. The second patient required 2 courses of ECT before improvement which was maintained on weekly ECT. Electroconvulsive therapy could be a potentially beneficial intervention in patients with ASD and severe challenging behaviors associated with catatonic symptoms including agitated or excited forms of catatonia.

  18. Determination of mixture valence plutonium and multicomponent by computer resolution analysis of absorption spectrum (UV/VIS/NIR) (CRAAS)

    International Nuclear Information System (INIS)

    Zhuang Weixin; Ye Guoan; Huang Lifeng; Sun Hongfang; Zhao Yanju

    1996-09-01

    A spectrophotometry has been developed which can directly determine a multi-component sample by spectrophotometry without any chemical separation. CRAAS (Computer Resolution Analysis of Absorption Spectrum) has been reported. It is different from the previous spectrophotometry depending on only one or several special absorption peak. The CRAAS deals with the whole region of absorption spectrum by mathematical statistics. So CRAAS has higher accuracy, stronger power and very high resolution. The trouble comes from overlap of different spectrum in each other has been solved because CRAAS depends on the whole spectrum. As long as two spectra have different shape, their concentrations can be determined even their special absorption peaks are seriously overlapped. The accuracy is about +-5%. (2 refs., 7 figs., 8 tabs.)

  19. Meta-Analysis of Studies Incorporating the Interests of Young Children with Autism Spectrum Disorders into Early Intervention Practices

    Directory of Open Access Journals (Sweden)

    Carl J. Dunst

    2012-01-01

    Full Text Available Incorporating the interests and preferences of young children with autism spectrum disorders into interventions to promote prosocial behavior and decrease behavior excesses has emerged as a promising practice for addressing the core features of autism. The efficacy of interest-based early intervention practices was examined in a meta-analysis of 24 studies including 78 children 2 to 6 years of age diagnosed with autism spectrum disorders. Effect size analyses of intervention versus nonintervention conditions and high-interest versus low-interest contrasts indicated that interest-based intervention practices were effective in terms of increasing prosocial and decreasing aberrant child behavior. Additionally, interest-based interventions that focused on two of the three core features of autism spectrum disorders (poor communication, poor interpersonal relationships were found most effective in influencing child outcomes. Implications for very early intervention are discussed in terms addressing the behavior markers of autism spectrum disorders before they become firmly established.

  20. A Novel approach for predicting monthly water demand by combining singular spectrum analysis with neural networks

    Science.gov (United States)

    Zubaidi, Salah L.; Dooley, Jayne; Alkhaddar, Rafid M.; Abdellatif, Mawada; Al-Bugharbee, Hussein; Ortega-Martorell, Sandra

    2018-06-01

    Valid and dependable water demand prediction is a major element of the effective and sustainable expansion of municipal water infrastructures. This study provides a novel approach to quantifying water demand through the assessment of climatic factors, using a combination of a pretreatment signal technique, a hybrid particle swarm optimisation algorithm and an artificial neural network (PSO-ANN). The Singular Spectrum Analysis (SSA) technique was adopted to decompose and reconstruct water consumption in relation to six weather variables, to create a seasonal and stochastic time series. The results revealed that SSA is a powerful technique, capable of decomposing the original time series into many independent components including trend, oscillatory behaviours and noise. In addition, the PSO-ANN algorithm was shown to be a reliable prediction model, outperforming the hybrid Backtracking Search Algorithm BSA-ANN in terms of fitness function (RMSE). The findings of this study also support the view that water demand is driven by climatological variables.

  1. Spectrum analysis of radiotracer residence time distribution for industrial and environmental applications

    International Nuclear Information System (INIS)

    Kasban, H.; Ashraf Hamid

    2014-01-01

    Radiotracer signal analysis and recognition still represents challenges in industrial and environmental applications specially in residence time distribution (RTD) measurement. This paper presents a development for the RTD signal recognition method that is based on power density spectrum (PDS). In this development, the features are extracted from the signals and/or from their higher-orders statistics (HOS) (Bispectrum and Trispectrum) instead of PDS. The HOS are estimated using direct, indirect and parametric estimations. The recognition results are analyzed and compared for different HOS estimation in order to select the best HOS estimation method for the purpose of RTD signal recognition. The artificial neural networks are used for training and testing of the proposed method. The proposed method is tested using RTD signals obtained from the measurements carried out using radiotracer technique. The simulation results show that the parametric estimation of the Trispectrum gives the higher recognition rate and is the most reliable for the RTD signal recognition. (author)

  2. Singular spectrum analysis in nonlinear dynamics, with applications to paleoclimatic time series

    Science.gov (United States)

    Vautard, R.; Ghil, M.

    1989-01-01

    Two dimensions of a dynamical system given by experimental time series are distinguished. Statistical dimension gives a theoretical upper bound for the minimal number of degrees of freedom required to describe the attractor up to the accuracy of the data, taking into account sampling and noise problems. The dynamical dimension is the intrinsic dimension of the attractor and does not depend on the quality of the data. Singular Spectrum Analysis (SSA) provides estimates of the statistical dimension. SSA also describes the main physical phenomena reflected by the data. It gives adaptive spectral filters associated with the dominant oscillations of the system and clarifies the noise characteristics of the data. SSA is applied to four paleoclimatic records. The principal climatic oscillations and the regime changes in their amplitude are detected. About 10 degrees of freedom are statistically significant in the data. Large noise and insufficient sample length do not allow reliable estimates of the dynamical dimension.

  3. Upper limits to trace constituents in Jupiter's atmosphere from an analysis of its 5 micrometer spectrum

    Science.gov (United States)

    Treffers, R. R.; Larson, H. P.; Fink, U.; Gautier, T. N.

    1978-01-01

    A high-resolution spectrum of Jupiter at 5 micrometers recorded at the Kuiper Airborne Observatory is used to determine upper limits to the column density of 19 molecules. The upper limits to the mixing ratios of SiH4, H2S, HCN, and simple hydrocarbons are discussed with respect to current models of Jupiter's atmosphere. These upper limits are compared to expectations based upon the solar abundance of the elements. This analysis permits upper limit measurements (SiH4), or actual detections (GeH4) of molecules with mixing ratios with hydrogen as low as 10 to the minus 9th power. In future observations at 5 micrometers the sensitivity of remote spectroscopic analyses should permit the study of constituents with mixing ratios as low as 10 to the minus 10th power, which would include the hydrides of such elements as Sn and As as well as numerous organic molecules.

  4. Prototype of an expert system to help nuclide identification in gamma spectrum analysis

    International Nuclear Information System (INIS)

    Jayanthi, Kasi Annapurna; Corcuera, Raquel Paviotti; Oliveira, Gina Maira B.

    1995-01-01

    This report describes the development and use of IDENT, prototype of an expert system that helps the researcher to identify radionuclides in gamma-ray spectroscopy. Normally the method adopted by the researcher is iterative, time consuming and becomes complicated in the analysis of large and complex gamma-ray spectra. The present expert system is based on the knowledge transmitted by expert and specialists in this area and the results show that it is helpful for researches who perform nuclide identification through gamma-ray spectroscopy. The gamma-ray spectrum of a material sample with about 140 peaks would take about a week or two be analysed by a specialist. The same task can be done in a few minutes using this expert system. (author). 14 refs., 2 figs

  5. Time Series Imputation via L1 Norm-Based Singular Spectrum Analysis

    Science.gov (United States)

    Kalantari, Mahdi; Yarmohammadi, Masoud; Hassani, Hossein; Silva, Emmanuel Sirimal

    Missing values in time series data is a well-known and important problem which many researchers have studied extensively in various fields. In this paper, a new nonparametric approach for missing value imputation in time series is proposed. The main novelty of this research is applying the L1 norm-based version of Singular Spectrum Analysis (SSA), namely L1-SSA which is robust against outliers. The performance of the new imputation method has been compared with many other established methods. The comparison is done by applying them to various real and simulated time series. The obtained results confirm that the SSA-based methods, especially L1-SSA can provide better imputation in comparison to other methods.

  6. Detection of Moving Targets Based on Doppler Spectrum Analysis Technique for Passive Coherent Radar

    Directory of Open Access Journals (Sweden)

    Zhao Yao-dong

    2013-06-01

    Full Text Available A novel method of moving targets detection taking Doppler spectrum analysis technique for Passive Coherent Radar (PCR is provided. After dividing the receiving signals into segments as pulse series, it utilizes the technique of pulse compress and Doppler processing to detect and locate the targets. Based on the algorithm for Pulse-Doppler (PD radar, the equipollence between continuous and pulsed wave in match filtering is proved and details of this method are introduced. To compare it with the traditional method of Cross-Ambiguity Function (CAF calculation, the relationship and mathematical modes of them are analyzed, with some suggestions on parameters choosing. With little influence to the gain of targets, the method can greatly promote the processing efficiency. The validity of the proposed method is demonstrated by offline processing real collected data sets and simulation results.

  7. Singular Spectrum Analysis for Astronomical Time Series: Constructing a Parsimonious Hypothesis Test

    Science.gov (United States)

    Greco, G.; Kondrashov, D.; Kobayashi, S.; Ghil, M.; Branchesi, M.; Guidorzi, C.; Stratta, G.; Ciszak, M.; Marino, F.; Ortolan, A.

    We present a data-adaptive spectral method - Monte Carlo Singular Spectrum Analysis (MC-SSA) - and its modification to tackle astrophysical problems. Through numerical simulations we show the ability of the MC-SSA in dealing with 1/f β power-law noise affected by photon counting statistics. Such noise process is simulated by a first-order autoregressive, AR(1) process corrupted by intrinsic Poisson noise. In doing so, we statistically estimate a basic stochastic variation of the source and the corresponding fluctuations due to the quantum nature of light. In addition, MC-SSA test retains its effectiveness even when a significant percentage of the signal falls below a certain level of detection, e.g., caused by the instrument sensitivity. The parsimonious approach presented here may be broadly applied, from the search for extrasolar planets to the extraction of low-intensity coherent phenomena probably hidden in high energy transients.

  8. Analysis of the red and green optical absorption spectrum of gas phase ammonia

    Science.gov (United States)

    Zobov, Nikolai F.; Coles, Phillip A.; Ovsyannikov, Roman I.; Kyuberis, Aleksandra A.; Hargreaves, Robert J.; Bernath, Peter F.; Tennyson, Jonathan; Yurchenko, Sergei N.; Polyansky, Oleg L.

    2018-04-01

    Room temperature NH3 absorption spectra recorded at the Kitt Peak National Solar Observatory in 1980 are analyzed. The spectra cover two regions in the visible: 15,200 - 15,700 cm-1 and 17,950 - 18,250 cm-1. These high overtone rotation-vibration spectra are analyzed using both combination differences and variational line lists. Two variational line lists were computed using the TROVE nuclear motion program: one is based on an ab initio potential energy surface (PES) while the other used a semi-empirical PES. Ab initio dipole moment surfaces are used in both cases. 95 energy levels with J = 1 - 7 are determined from analysis of the experimental spectrum in the 5νNH (red) region and 46 for 6νNH (green) region. These levels span four vibrational bands in each of the two regions, associated with stretching overtones.

  9. Response inhibition and interference control in obsessive-compulsive spectrum disorders

    Directory of Open Access Journals (Sweden)

    Laura S van Velzen

    2014-06-01

    Full Text Available Over the past twenty years, motor response inhibition and interference control have received considerable scientific effort and attention, due to their important role in behavior and the development of neuropsychiatric disorders. Results of neuroimaging studies indicate that motor response inhibition and interference control are dependent on cortical-striatal-thalamic-cortical (CSTC circuits. Structural and functional abnormalities within the CSTC circuits have been reported for many neuropsychiatric disorders, including obsessive-compulsive disorder (OCD and related disorders, such as attention deficit hyperactivity disorder (ADHD, Tourette’s syndrome (TS and trichotillomania. These disorders also share impairments in motor response inhibition and interference control, which may underlie some of their behavioral and cognitive symptoms. Results of task-related neuroimaging studies on inhibitory functions in these disorders show that impaired task performance is related to altered recruitment of the CSTC circuits. Previous research has shown that inhibitory performance is dependent upon dopamine, noradrenaline and serotonin signaling, neurotransmitters that have been implicated in the pathophysiology of these disorders. In this review we discuss the common and disorder-specific pathophysiological mechanisms of inhibition-related dysfunction in OCD and related disorders.

  10. Steroid-Responsive Epilepsia Partialis Continua with Anti-Thyroid Antibodies: A Spectrum of Hashimoto's Encephalopathy

    Directory of Open Access Journals (Sweden)

    Hiroki Masuda

    2014-05-01

    Full Text Available Background: When a neuropsychiatric symptom due to encephalopathy develops in a patient with anti-thyroid antibodies, especially when the symptom is steroid-responsive, Hashimoto's encephalopathy (HE needs to be included in the differential diagnosis of the patient. Although HE is an elusive disease, it is thought to cause various clinical presentations including seizures, myoclonus, and epilepsia partialis continua (EPC. Case Report: We present the case of a 33-year-old Japanese woman who acutely developed EPC in the right hand as an isolated manifestation. A thyroid ultrasound showed an enlarged hypoechogenic gland, and a thyroid status assessment showed euthyroid with high titers of thyroid antibodies. A brain MRI revealed a nodular lesion in the left precentral gyrus. Corticosteroid treatment resulted in a cessation of the symptom. Conclusions: A precentral nodular lesion can be responsible for steroid-responsive EPC in a patient with anti-thyroid antibodies and may be caused by HE. The serial MRI findings of our case suggest the presence of primary demyelination, with ischemia possibly due to vasculitis around the demyelinating lesion.

  11. The effect of epilepsy on autistic symptom severity assessed by the social responsiveness scale in children with autism spectrum disorder.

    Science.gov (United States)

    Ko, Chanyoung; Kim, Namwook; Kim, Eunjoo; Song, Dong Ho; Cheon, Keun-Ah

    2016-06-27

    As the prevalence of autism spectrum disorders in people with epilepsy ranges from 15 to 47 % (Clarke et al. in Epilepsia 46:1970-1977, 2005), it is speculated that there is a special relationship between the two disorders, yet there has been a lack of systematic studies comparing the behavioral phenotype between autistic individuals and autistic individuals with epilepsy. This study aims to investigate how the co-occurrence of epilepsy and Autism Spectrum Disorder (ASD) affects autistic characteristics assessed by the Social Responsiveness Scale (SRS), which has been used as a measure of autism symptoms in previous studies. In this research we referred to all individuals with Autism or Autistic Disorder as individuals with ASD. We reviewed the complete medical records of 182 participants who presented to a single tertiary care referral center from January 1, 2013 to July 28, 2015, and subsequently received complete child and adolescent psychiatric assessments. Of the 182 participants, 22 were diagnosed with Autism Spectrum Disorder and epilepsy. Types of epilepsy observed in these individuals included complex partial seizure, generalized tonic-clonic seizure, or infantile spasm. Using 'Propensity Score Matching' we selected 44 children, diagnosed with only Autism Spectrum Disorder, whose age, gender, and intelligence quotient (IQ) were closely matched with the 22 children diagnosed with Autism Spectrum Disorder and epilepsy. Social functioning of participants was assessed by the social responsiveness scale, which consists of five categories: social awareness, social cognition, social communication, social motivation, and autistic mannerisms. Bivariate analyses were conducted to compare the ASD participants with epilepsy group with the ASD-only group on demographic and clinical characteristics. Chi square and t test p values were calculated when appropriate. There was no significant difference in age (p = 0.172), gender (p > 0.999), IQ (FSIQ, p = 0.139; VIQ

  12. The Maximum Entropy Method for Optical Spectrum Analysis of Real-Time TDDFT

    International Nuclear Information System (INIS)

    Toogoshi, M; Kano, S S; Zempo, Y

    2015-01-01

    The maximum entropy method (MEM) is one of the key techniques for spectral analysis. The major feature is that spectra in the low frequency part can be described by the short time-series data. Thus, we applied MEM to analyse the spectrum from the time dependent dipole moment obtained from the time-dependent density functional theory (TDDFT) calculation in real time. It is intensively studied for computing optical properties. In the MEM analysis, however, the maximum lag of the autocorrelation is restricted by the total number of time-series data. We proposed that, as an improved MEM analysis, we use the concatenated data set made from the several-times repeated raw data. We have applied this technique to the spectral analysis of the TDDFT dipole moment of ethylene and oligo-fluorene with n = 8. As a result, the higher resolution can be obtained, which is closer to that of FT with practically time-evoluted data as the same total number of time steps. The efficiency and the characteristic feature of this technique are presented in this paper. (paper)

  13. Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response.

    Science.gov (United States)

    Stellmann, Jan-Patrick; Krumbholz, Markus; Friede, Tim; Gahlen, Anna; Borisow, Nadja; Fischer, Katrin; Hellwig, Kerstin; Pache, Florence; Ruprecht, Klemens; Havla, Joachim; Kümpfel, Tania; Aktas, Orhan; Hartung, Hans-Peter; Ringelstein, Marius; Geis, Christian; Kleinschnitz, Christoph; Berthele, Achim; Hemmer, Bernhard; Angstwurm, Klemens; Young, Kim Lea; Schuster, Simon; Stangel, Martin; Lauda, Florian; Tumani, Hayrettin; Mayer, Christoph; Zeltner, Lena; Ziemann, Ulf; Linker, Ralf Andreas; Schwab, Matthias; Marziniak, Martin; Then Bergh, Florian; Hofstadt-van Oy, Ulrich; Neuhaus, Oliver; Zettl, Uwe; Faiss, Jürgen; Wildemann, Brigitte; Paul, Friedemann; Jarius, Sven; Trebst, Corinna; Kleiter, Ingo

    2017-08-01

    To analyse predictors for relapses and number of attacks under different immunotherapies in patients with neuromyelitis optica spectrum disorder (NMOSD). This is a retrospective cohort study conducted in neurology departments at 21 regional and university hospitals in Germany. Eligible participants were patients with aquaporin-4-antibody-positive or aquaporin-4-antibody-negative NMOSD. Main outcome measures were HRs from Cox proportional hazard regression models adjusted for centre effects, important prognostic factors and repeated treatment episodes. 265 treatment episodes with a mean duration of 442 days (total of 321 treatment years) in 144 patients (mean age at first attack: 40.9 years, 82.6% female, 86.1% aquaporin-4-antibody-positive) were analysed. 191 attacks occurred during any of the treatments (annual relapse rate=0.60). The most common treatments were rituximab (n=77, 111 patient-years), azathioprine (n=52, 68 patient-years), interferon-β (n=32, 61 patient-years), mitoxantrone (n=34, 32.1 patient-years) and glatiramer acetate (n=17, 10 patient-years). Azathioprine (HR=0.4, 95% CI 0.3 to 0.7, p=0.001) and rituximab (HR=0.6, 95% CI 0.4 to 1.0, p=0.034) reduced the attack risk compared with interferon-β, whereas mitoxantrone and glatiramer acetate did not. Patients who were aquaporin-4-antibody-positive had a higher risk of attacks (HR=2.5, 95% CI 1.3 to 5.1, p=0.009). Every decade of age was associated with a lower risk for attacks (HR=0.8, 95% CI 0.7 to 1.0, p=0.039). A previous attack under the same treatment tended to be predictive for further attacks (HR=1.5, 95% CI 1.0 to 2.4, p=0.065). Age, antibody status and possibly previous attacks predict further attacks in patients treated for NMOSD. Azathioprine and rituximab are superior to interferon-β. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  14. Gamma-ray Full Spectrum Analysis for Environmental Radioactivity by HPGe Detector

    Science.gov (United States)

    Jeong, Meeyoung; Lee, Kyeong Beom; Kim, Kyeong Ja; Lee, Min-Kie; Han, Ju-Bong

    2014-12-01

    Odyssey, one of the NASA¡¯s Mars exploration program and SELENE (Kaguya), a Japanese lunar orbiting spacecraft have a payload of Gamma-Ray Spectrometer (GRS) for analyzing radioactive chemical elements of the atmosphere and the surface. In these days, gamma-ray spectroscopy with a High-Purity Germanium (HPGe) detector has been widely used for the activity measurements of natural radionuclides contained in the soil of the Earth. The energy spectra obtained by the HPGe detectors have been generally analyzed by means of the Window Analysis (WA) method. In this method, activity concentrations are determined by using the net counts of energy window around individual peaks. Meanwhile, an alternative method, the so-called Full Spectrum Analysis (FSA) method uses count numbers not only from full-absorption peaks but from the contributions of Compton scattering due to gamma-rays. Consequently, while it takes a substantial time to obtain a statistically significant result in the WA method, the FSA method requires a much shorter time to reach the same level of the statistical significance. This study shows the validation results of FSA method. We have compared the concentration of radioactivity of 40K, 232Th and 238U in the soil measured by the WA method and the FSA method, respectively. The gamma-ray spectrum of reference materials (RGU and RGTh, KCl) and soil samples were measured by the 120% HPGe detector with cosmic muon veto detector. According to the comparison result of activity concentrations between the FSA and the WA, we could conclude that FSA method is validated against the WA method. This study implies that the FSA method can be used in a harsh measurement environment, such as the gamma-ray measurement in the Moon, in which the level of statistical significance is usually required in a much shorter data acquisition time than the WA method.

  15. Multifractal spectrum analysis of nonlinear dynamical mechanisms in China’s agricultural futures markets

    Science.gov (United States)

    Chen, Shu-Peng; He, Ling-Yun

    2010-04-01

    Based on Partition Function and Multifractal Spectrum Analysis, we investigated the nonlinear dynamical mechanisms in China’s agricultural futures markets, namely, Dalian Commodity Exchange (DCE for short) and Zhengzhou Commodity Exchange (ZCE for short), where nearly all agricultural futures contracts are traded in the two markets. Firstly, we found nontrivial multifractal spectra, which are the empirical evidence of the existence of multifractal features, in 4 representative futures markets in China, that is, Hard Winter wheat (HW for short) and Strong Gluten wheat (SG for short) futures markets from ZCE and Soy Meal (SM for short) futures and Soy Bean No.1 (SB for short) futures markets from DCE. Secondly, by shuffling the original time series, we destroyed the underlying nonlinear temporal correlation; thus, we identified that long-range correlation mechanism constitutes major contributions in the formation in the multifractals of the markets. Thirdly, by tracking the evolution of left- and right-half spectra, we found that there exist critical points, between which there are different behaviors, in the left-half spectra for large price fluctuations; but for the right-hand spectra for small price fluctuations, the width of those increases slowly as the delay t increases in the long run. Finally, the dynamics of large fluctuations is significantly different from that of the small ones, which implies that there exist different underlying mechanisms in the formation of multifractality in the markets. Our main contributions focus on that we not only provided empirical evidence of the existence of multifractal features in China agricultural commodity futures markets; but also we pioneered in investigating the sources of the multifractality in China’s agricultural futures markets in current literature; furthermore, we investigated the nonlinear dynamical mechanisms based on spectrum analysis, which offers us insights into the underlying dynamical mechanisms in

  16. Gamma-ray Full Spectrum Analysis for Environmental Radioactivity by HPGe Detector

    Directory of Open Access Journals (Sweden)

    Meeyoung Jeong

    2014-12-01

    Full Text Available Odyssey, one of the NASA’s Mars exploration program and SELENE (Kaguya, a Japanese lunar orbiting spacecraft have a payload of Gamma-Ray Spectrometer (GRS for analyzing radioactive chemical elements of the atmosphere and the surface. In these days, gamma-ray spectroscopy with a High-Purity Germanium (HPGe detector has been widely used for the activity measurements of natural radionuclides contained in the soil of the Earth. The energy spectra obtained by the HPGe detectors have been generally analyzed by means of the Window Analysis (WA method. In this method, activity concentrations are determined by using the net counts of energy window around individual peaks. Meanwhile, an alternative method, the so-called Full Spectrum Analysis (FSA method uses count numbers not only from full-absorption peaks but from the contributions of Compton scattering due to gamma-rays. Consequently, while it takes a substantial time to obtain a statistically significant result in the WA method, the FSA method requires a much shorter time to reach the same level of the statistical significance. This study shows the validation results of FSA method. We have compared the concentration of radioactivity of 40K, 232Th and 238U in the soil measured by the WA method and the FSA method, respectively. The gamma-ray spectrum of reference materials (RGU and RGTh, KCl and soil samples were measured by the 120% HPGe detector with cosmic muon veto detector. According to the comparison result of activity concentrations between the FSA and the WA, we could conclude that FSA method is validated against the WA method. This study implies that the FSA method can be used in a harsh measurement environment, such as the gamma-ray measurement in the Moon, in which the level of statistical significance is usually required in a much shorter data acquisition time than the WA method.

  17. Post hoc analysis of plasma amino acid profiles: towards a specific pattern in autism spectrum disorder and intellectual disability.

    Science.gov (United States)

    Delaye, Jean-Baptiste; Patin, Franck; Lagrue, Emmanuelle; Le Tilly, Olivier; Bruno, Clement; Vuillaume, Marie-Laure; Raynaud, Martine; Benz-De Bretagne, Isabelle; Laumonnier, Frederic; Vourc'h, Patrick; Andres, Christian; Blasco, Helene

    2018-01-01

    Objectives Autism spectrum disorders and intellectual disability present a challenge for therapeutic and dietary management. We performed a re-analysis of plasma amino acid chromatography of children with autism spectrum disorders ( n = 22) or intellectual disability ( n = 29) to search for a metabolic signature that can distinguish individuals with these disorders from controls ( n = 30). Methods We performed univariate and multivariate analyses using different machine learning strategies, from the raw data of the amino acid chromatography. Finally, we analysed the metabolic pathways associated with discriminant biomarkers. Results Multivariate analysis revealed models to discriminate patients with autism spectrum disorders or intellectual disability and controls from plasma amino acid profiles ( P intellectual disability patients shared similar differences relative to controls, including lower glutamate ( P intellectual disability revealed the involvement of urea, 3-methyl-histidine and histidine metabolism. Biosigner analysis and univariate analysis confirmed the role of 3-methylhistidine ( P = 0.004), histidine ( P = 0.003), urea ( P = 0.0006) and lysine ( P = 0.002). Conclusions We revealed discriminant metabolic patterns between autism spectrum disorders, intellectual disability and controls. Amino acids known to play a role in neurotransmission were discriminant in the models comparing autism spectrum disorders or intellectual disability to controls, and histidine and b-alanine metabolism was specifically highlighted in the model.

  18. Behavioral and physiological responses to child-directed speech as predictors of communication outcomes in children with autism spectrum disorders.

    Science.gov (United States)

    Watson, Linda R; Baranek, Grace T; Roberts, Jane E; David, Fabian J; Perryman, Twyla Y

    2010-08-01

    To determine the extent to which behavioral and physiological responses during child-directed speech (CDS) correlate concurrently and predictively with communication skills in young children with autism spectrum disorders (ASD). Twenty-two boys with ASD (initial mean age: 35 months) participated in a longitudinal study. At entry, behavioral (i.e., percentage looking) and physiological (i.e., vagal activity) measures were collected during the presentation of CDS stimuli. A battery of standardized communication measures was administered at entry and readministered 12 months later. Percentage looking during CDS was strongly correlated with all entry and follow-up communication scores; vagal activity during CDS was moderately to strongly correlated with entry receptive language, follow-up expressive language, and social-communicative adaptive skills. After controlling for entry communication skills, vagal activity during CDS accounted for significant variance in follow-up communication skills, but percentage looking during CDS did not. Behavioral and physiological responses to CDS are significantly related to concurrent and later communication skills of children with ASD. Furthermore, higher vagal activity during CDS predicts better communication outcomes 12 months later, after initial communication skills are accounted for. Further research is needed to better understand the physiological mechanisms underlying variable responses to CDS among children with ASD.

  19. Atypical lateralization of ERP response to native and non-native speech in infants at risk for autism spectrum disorder.

    Science.gov (United States)

    Seery, Anne M; Vogel-Farley, Vanessa; Tager-Flusberg, Helen; Nelson, Charles A

    2013-07-01

    Language impairment is common in autism spectrum disorders (ASD) and is often accompanied by atypical neural lateralization. However, it is unclear when in development language impairment or atypical lateralization first emerges. To address these questions, we recorded event-related-potentials (ERPs) to native and non-native speech contrasts longitudinally in infants at risk for ASD (HRA) over the first year of life to determine whether atypical lateralization is present as an endophenotype early in development and whether these infants show delay in a very basic precursor of language acquisition: phonemic perceptual narrowing. ERP response for the HRA group to a non-native speech contrast revealed a trajectory of perceptual narrowing similar to a group of low-risk controls (LRC), suggesting that phonemic perceptual narrowing does not appear to be delayed in these high-risk infants. In contrast there were significant group differences in the development of lateralized ERP response to speech: between 6 and 12 months the LRC group displayed a lateralized response to the speech sounds, while the HRA group failed to display this pattern. We suggest the possibility that atypical lateralization to speech may be an ASD endophenotype over the first year of life. Copyright © 2012 Elsevier Ltd. All rights reserved.

  20. Seismic response analysis with liquid-structure interaction

    International Nuclear Information System (INIS)

    Thomas, R.G.; Harrop, L.P.

    1983-06-01

    A linear transient finite element stress analysis of a water filled tank has been carried out using the proprietary computer code ANSYS. The containment structure was represented as rigidly fixed to ground. The flexibility of the tank wall was modelled together with the hydrostatic and hydrodynamic effects of the water contents and attached concentrated masses. The foundations were considered to be laid in solid rock, and no soil-structure interaction effects were included. The seismic input was a ground response spectrum conservatively representing both the Temblor and Parkfield modified time history records. It was found that the response of the structure was greatest at the front end (furthest from the point at which the tank is connected to a rigid internal structure), and that this was dominated by the fundamental mode. Higher modes are important at the back end. Buckling at the front end of the tank has been identified as a potential failure mechanism, and attention has also been called to the tensile capacity of the wall to base junction in this region. The requirement for a proper criterion against which to assess the margin against plastic collapse in a safe shutdown analysis has been noted. In certain regions the structure does not shake-down under the repeated reversed cyclic loading, and the need for an assessment of the implications of this for fatigue resistance has been indicated. (author)

  1. Direct analysis of quantal radiation response data

    International Nuclear Information System (INIS)

    Thames, H.D. Jr.; Rozell, M.E.; Tucker, S.L.; Ang, K.K.; Travis, E.L.; Fisher, D.R.

    1986-01-01

    A direct analysis is proposed for quantal (all-or-nothing) responses to fractionated radiation and endpoint-dilution assays of cell survival. As opposed to two-step methods such as the reciprocal-dose technique, in which ED 50 values are first estimated for different fractionation schemes and then fit (as reciprocals) against dose per fraction, all raw data are included in a single maximum-likelihood treatment. The method accommodates variations such as short-interval fractionation regimens designed to determine tissue repair kinetics, tissue response to continuous exposures, and data obtained using endpoint-dilution assays of cell survival after fractionated doses. Monte-Carlo techniques were used to compare the direct and reciprocal-dose methods for analysis of small-scale and large-scale studies of response to fractionated doses. Both methods tended toward biased estimates in the analysis of small-scale (3 fraction numbers) studies. The α/β ratios showed less scatter when estimated by the direct method. The 95% confidence intervals determined by the direct method were more appropriate than those determined by reciprocal-dose analysis, for which 18% (small-scale study) or 8% (large-scale study) of the confidence intervals did not include the 'true' value of α/β. (author)

  2. Chemosensitivity of walking legs of the lobster Homarus americanus: neurophysiological response spectrum and thresholds

    Energy Technology Data Exchange (ETDEWEB)

    Derby, C D; Atema, J

    1982-01-01

    Responses of chemoreceptors in the walking legs of the lobster Homarus americanus to 35 individual compounds and 3 mixtures (prey odours and extracts) were studied using extracellular recording techniques. Compared against a standard mussel (Mytilus edulis) extract, these receptors were most sensitive to the amino acids L-glutamate, hydroxy-L-proline, L-aspartate, L-arginine, glycine, taurine, and L-alanine, as well as such other compounds as ammonium chloride, betaine, and the tripeptide glutathione. Most of these excitants are among those compounds most prevalent in the prey of lobsters.

  3. Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls.

    Directory of Open Access Journals (Sweden)

    Li Liu

    2013-04-01

    Full Text Available We report on results from whole-exome sequencing (WES of 1,039 subjects diagnosed with autism spectrum disorders (ASD and 870 controls selected from the NIMH repository to be of similar ancestry to cases. The WES data came from two centers using different methods to produce sequence and to call variants from it. Therefore, an initial goal was to ensure the distribution of rare variation was similar for data from different centers. This proved straightforward by filtering called variants by fraction of missing data, read depth, and balance of alternative to reference reads. Results were evaluated using seven samples sequenced at both centers and by results from the association study. Next we addressed how the data and/or results from the centers should be combined. Gene-based analyses of association was an obvious choice, but should statistics for association be combined across centers (meta-analysis or should data be combined and then analyzed (mega-analysis? Because of the nature of many gene-based tests, we showed by theory and simulations that mega-analysis has better power than meta-analysis. Finally, before analyzing the data for association, we explored the impact of population structure on rare variant analysis in these data. Like other recent studies, we found evidence that population structure can confound case-control studies by the clustering of rare variants in ancestry space; yet, unlike some recent studies, for these data we found that principal component-based analyses were sufficient to control for ancestry and produce test statistics with appropriate distributions. After using a variety of gene-based tests and both meta- and mega-analysis, we found no new risk genes for ASD in this sample. Our results suggest that standard gene-based tests will require much larger samples of cases and controls before being effective for gene discovery, even for a disorder like ASD.

  4. Analysis of Rare, Exonic Variation amongst Subjects with Autism Spectrum Disorders and Population Controls

    Science.gov (United States)

    Liu, Li; Sabo, Aniko; Neale, Benjamin M.; Nagaswamy, Uma; Stevens, Christine; Lim, Elaine; Bodea, Corneliu A.; Muzny, Donna; Reid, Jeffrey G.; Banks, Eric; Coon, Hillary; DePristo, Mark; Dinh, Huyen; Fennel, Tim; Flannick, Jason; Gabriel, Stacey; Garimella, Kiran; Gross, Shannon; Hawes, Alicia; Lewis, Lora; Makarov, Vladimir; Maguire, Jared; Newsham, Irene; Poplin, Ryan; Ripke, Stephan; Shakir, Khalid; Samocha, Kaitlin E.; Wu, Yuanqing; Boerwinkle, Eric; Buxbaum, Joseph D.; Cook, Edwin H.; Devlin, Bernie; Schellenberg, Gerard D.; Sutcliffe, James S.; Daly, Mark J.; Gibbs, Richard A.; Roeder, Kathryn

    2013-01-01

    We report on results from whole-exome sequencing (WES) of 1,039 subjects diagnosed with autism spectrum disorders (ASD) and 870 controls selected from the NIMH repository to be of similar ancestry to cases. The WES data came from two centers using different methods to produce sequence and to call variants from it. Therefore, an initial goal was to ensure the distribution of rare variation was similar for data from different centers. This proved straightforward by filtering called variants by fraction of missing data, read depth, and balance of alternative to reference reads. Results were evaluated using seven samples sequenced at both centers and by results from the association study. Next we addressed how the data and/or results from the centers should be combined. Gene-based analyses of association was an obvious choice, but should statistics for association be combined across centers (meta-analysis) or should data be combined and then analyzed (mega-analysis)? Because of the nature of many gene-based tests, we showed by theory and simulations that mega-analysis has better power than meta-analysis. Finally, before analyzing the data for association, we explored the impact of population structure on rare variant analysis in these data. Like other recent studies, we found evidence that population structure can confound case-control studies by the clustering of rare variants in ancestry space; yet, unlike some recent studies, for these data we found that principal component-based analyses were sufficient to control for ancestry and produce test statistics with appropriate distributions. After using a variety of gene-based tests and both meta- and mega-analysis, we found no new risk genes for ASD in this sample. Our results suggest that standard gene-based tests will require much larger samples of cases and controls before being effective for gene discovery, even for a disorder like ASD. PMID:23593035

  5. Development of an Automated LIBS Analytical Test System Integrated with Component Control and Spectrum Analysis Capabilities

    International Nuclear Information System (INIS)

    Ding Yu; Tian Di; Chen Feipeng; Chen Pengfei; Qiao Shujun; Yang Guang; Li Chunsheng

    2015-01-01

    The present paper proposes an automated Laser-Induced Breakdown Spectroscopy (LIBS) analytical test system, which consists of a LIBS measurement and control platform based on a modular design concept, and a LIBS qualitative spectrum analysis software and is developed in C#. The platform provides flexible interfacing and automated control; it is compatible with different manufacturer component models and is constructed in modularized form for easy expandability. During peak identification, a more robust peak identification method with improved stability in peak identification has been achieved by applying additional smoothing on the slope obtained by calculation before peak identification. For the purpose of element identification, an improved main lines analysis method, which detects all elements on the spectral peak to avoid omission of certain elements without strong spectral lines, is applied to element identification in the tested LIBS samples. This method also increases the identification speed. In this paper, actual applications have been carried out. According to tests, the analytical test system is compatible with components of various models made by different manufacturers. It can automatically control components to get experimental data and conduct filtering, peak identification and qualitative analysis, etc. on spectral data. (paper)

  6. Statistical Analysis of Solar PV Power Frequency Spectrum for Optimal Employment of Building Loads

    Energy Technology Data Exchange (ETDEWEB)

    Olama, Mohammed M [ORNL; Sharma, Isha [ORNL; Kuruganti, Teja [ORNL; Fugate, David L [ORNL

    2017-01-01

    In this paper, a statistical analysis of the frequency spectrum of solar photovoltaic (PV) power output is conducted. This analysis quantifies the frequency content that can be used for purposes such as developing optimal employment of building loads and distributed energy resources. One year of solar PV power output data was collected and analyzed using one-second resolution to find ideal bounds and levels for the different frequency components. The annual, seasonal, and monthly statistics of the PV frequency content are computed and illustrated in boxplot format. To examine the compatibility of building loads for PV consumption, a spectral analysis of building loads such as Heating, Ventilation and Air-Conditioning (HVAC) units and water heaters was performed. This defined the bandwidth over which these devices can operate. Results show that nearly all of the PV output (about 98%) is contained within frequencies lower than 1 mHz (equivalent to ~15 min), which is compatible for consumption with local building loads such as HVAC units and water heaters. Medium frequencies in the range of ~15 min to ~1 min are likely to be suitable for consumption by fan equipment of variable air volume HVAC systems that have time constants in the range of few seconds to few minutes. This study indicates that most of the PV generation can be consumed by building loads with the help of proper control strategies, thereby reducing impact on the grid and the size of storage systems.

  7. Rapid assessment of populations trends of invasive species: Singular Spectrum Analysis (SSA

    Directory of Open Access Journals (Sweden)

    DANA, ED

    2010-01-01

    Full Text Available Singular Spectrum Analysis (SSA is a powerful analytical approach for biodi-versity management. Its main advan-tages are due to its intuitive processing and visualization, since mathematical workflow is conceptually similar to the widely accepted Principal Components Analysis. Detailed analyses of popula-tion trends with mathematical tools are often difficult to achieve for managers by a number of reasons (large numbers or areas monitored, large number of species, insufficient statistics skills, strong knowledge level in demographic analyses, etc.. SSA has been used since the 1970’s in signal processing to clarify signal vs. noisy information, but it has also been used in climate change analy-sis and other developmental areas. Be-sides, SSA is a rapid-learning method for technicians and managers with medium level of mathematical knowledge. Free software in Unix environment is avail-able. Unfortunately, no free and friendly software is available for Win-dows SO. Although R package may offer solutions for really advanced users, it does not fit real work situations for managers of biological invasions. Cater-pillar (Gistat Group, Ltd is by now, the best option found by the author in terms of price, facility for results inter-pretation and time consumed in learn-ing. The main disadvantage is the poor content of tutorial files

  8. Modelling structural systems for transient response analysis

    International Nuclear Information System (INIS)

    Melosh, R.J.

    1975-01-01

    This paper introduces and reports success of a direct means of determining the time periods in which a structural system behaves as a linear system. Numerical results are based on post fracture transient analyses of simplified nuclear piping systems. Knowledge of the linear response ranges will lead to improved analysis-test correlation and more efficient analyses. It permits direct use of data from physical tests in analysis and simplication of the analytical model and interpretation of its behavior. The paper presents a procedure for deducing linearity based on transient responses. Given the forcing functions and responses of discrete points of the system at various times, the process produces evidence of linearity and quantifies an adequate set of equations of motion. Results of use of the process with linear and nonlinear analyses of piping systems with damping illustrate its success. Results cover the application to data from mathematical system responses. The process is successfull with mathematical models. In loading ranges in which all modes are excited, eight digit accuracy of predictions are obtained from the equations of motion deduced. Small changes (less than 0.01%) in the norm of the transfer matrices are produced by manipulation errors for linear systems yielding evidence that nonlinearity is easily distinguished. Significant changes (greater than five %) are coincident with relatively large norms of the equilibrium correction vector in nonlinear analyses. The paper shows that deducing linearity and, when admissible, quantifying linear equations of motion from transient response data for piping systems can be achieved with accuracy comparable to that of response data

  9. The expanding spectrum of clinically-distinctive, immunotherapy-responsive autoimmune encephalopathies

    Directory of Open Access Journals (Sweden)

    Sarosh R Irani

    2012-04-01

    Full Text Available The autoimmune encephalopathies are a group of conditions that are associated with autoantibodies against surface neuronal proteins, which are likely to mediate the disease. They are established as a frequent cause of encephalitis. Characteristic clinical features in individual patients often allow the specificity of the underlying antibody to be confidently predicted. Antibodies against the VGKC-complex, mainly LGI1(leucine-rich glioma-inactivated 1, CASPR2 (contactin-associated protein 2, and contactin-2, and NMDA (N-methyl, D-aspartate -receptor are the most frequently established serological associations. In the minority of cases, an underlying tumour can be responsible. Early administration of immunotherapies, and tumour removal, where it is relevant, offer the greatest chance of improvement. Prolonged courses of immunotherapies may be required, and clinical improvements often correlate well with the antibody levels. In the present article, we have summarised recent developments in the clinical and laboratory findings within this rapidly expanding field.

  10. [Application of wavelet transform and neural network in the near-infrared spectrum analysis of oil shale].

    Science.gov (United States)

    Li, Su-Yi; Ji, Yan-Ju; Liu, Wei-Yu; Wang, Zhi-Hong

    2013-04-01

    In the present study, an innovative method is proposed, employing both wavelet transform and neural network, to analyze the near-infrared spectrum data in oil shale survey. The method entails using db8 wavelet at 3 levels decomposition to process raw data, using the transformed data as the input matrix, and creating the model through neural network. To verify the validity of the method, this study analyzes 30 synthesized oil shale samples, in which 20 samples are randomly selected for network training, the other 10 for model prediction, and uses the full spectrum and the wavelet transformed spectrum to carry out 10 network models, respectively. Results show that the mean speed of the full spectrum neural network modeling is 570.33 seconds, and the predicted residual sum of squares (PRESS) and correlation coefficient of prediction are 0.006 012 and 0.843 75, respectively. In contrast, the mean speed of the wavelet network modeling method is 3.15 seconds, and the mean PRESS and correlation coefficient of prediction are 0.002 048 and 0.953 19, respectively. These results demonstrate that the wavelet neural network modeling method is significantly superior to the full spectrum neural network modeling method. This study not only provides a new method for more efficient and accurate detection of the oil content of oil shale, but also indicates the potential for applying wavelet transform and neutral network in broad near-infrared spectrum analysis.

  11. Analysis of Practical Implementation for Secure Spectrum Sensing in Cognitive Radio Networks

    DEFF Research Database (Denmark)

    Ivanov, Antoni; Mihovska, Albena Dimitrova; Tonchev, Krasimir

    2017-01-01

    Spectrum sensing is vitally important functionality for the cognitive radio (CR) device because it allows for assessing, which part of the spectrum is unoccupied and suitable for temporal use. Most of the proposed research efforts until now have been based on theoretical findings about the perfor......Spectrum sensing is vitally important functionality for the cognitive radio (CR) device because it allows for assessing, which part of the spectrum is unoccupied and suitable for temporal use. Most of the proposed research efforts until now have been based on theoretical findings about...

  12. Exploring links between genotypes, phenotypes, and clinical predictors of response to early intensive behavioural intervention in Autism Spectrum Disorder

    Directory of Open Access Journals (Sweden)

    Valsamma eEapen

    2013-09-01

    Full Text Available Autism Spectrum Disorder (ASD is amongst the most familial of psychiatric disorders. Twin and family studies have demonstrated a monozygotic concordance rate of 70–90%, dizygotic concordance of around 10% and more than a 20-fold increase in risk for first-degree relatives. Despite major advances in the genetics of autism, the relationship between different aspects of the behavioural and cognitive phenotype and their underlying genetic liability is still unclear. This is complicated by the heterogeneity of autism, which exists at both genetic and phenotypic levels. Given this heterogeneity, one method to find homogeneous entities and link these with specific genotypes would be to pursue endophenotypes. Evidence from neuroimaging, eye tracking and electrophysiology studies supports the hypothesis that, building on genetic vulnerability, ASD emerges from a developmental cascade in which a deficit in attention to social stimuli leads to impaired interactions with primary caregivers. This results in abnormal development of the neurocircuitry responsible for social cognition, which in turn adversely affects later behavioural and functional domains dependent on these early processes, such as language development. Such a model begets a heterogeneous clinical phenotype, and is also supported by studies demonstrating better clinical outcomes with earlier treatment. Treatment response following intensive early behavioural intervention in ASD is also distinctly variable; however, relatively little is known about specific elements of the clinical phenotype that may predict response to current behavioural treatments. This paper overviews the literature regarding genotypes, phenotypes and predictors of response to behavioural intervention in ASD and presents suggestions for future research to explore linkages between these that would enable better identification of, and increased treatment efficacy for, ASD.

  13. Development of analytical software for semi-quantitative analysis of x-ray spectrum acquired from energy-dispersive spectrometer

    International Nuclear Information System (INIS)

    Karim, A.; Rana, M.A.; Qamar, R.; Latif, A; Ahmad, M.; Farooq, M.A.; Ahmad, Z.

    2003-12-01

    Software package for elemental analysis for X-ray spectrum obtained from Energy Dispersive Spectrometer (EDS) attached with Scanning Electron Microscope (SEM) has been developed: A Personal Computer Analyzer card PCA-800 is used to acquire data from the EDS. This spectrum is obtained in binary format, which is transformed into ASCII format using PCAII card software. The program is modular in construction and coded using Microsoft's QUICKBASIC compiler linker. Energy line library containing all lines of elements is created for analysis of acquired characteristic X-ray spectrum. Two techniques of peak identification are provided. Statistical tools are employed for smoothing of a curve and for computing area under the curve. Elemental concentration is calculated in weight % and in atomic. (author)

  14. Metacognition Is Necessary for the Emergence of Motivation in People With Schizophrenia Spectrum Disorders: A Necessary Condition Analysis.

    Science.gov (United States)

    Luther, Lauren; Bonfils, Kelsey A; Firmin, Ruth L; Buck, Kelly D; Choi, Jimmy; Dimaggio, Giancarlo; Popolo, Raffaele; Minor, Kyle S; Lysaker, Paul H

    2017-12-01

    Metacognition deficits are a putative cause of reduced motivation in people with schizophrenia spectrum disorders. However, it is unclear whether certain levels of metacognition are necessary for motivation to emerge. This study used a Necessary Condition Analysis to test whether metacognition was necessary for the presence of motivation and to identify the minimum level of metacognition necessary for high motivation to be possible in people with schizophrenia spectrum disorders (N = 175). Participants completed clinician-rated measures of metacognition and motivation. Necessary Condition Analysis revealed that metacognition is a necessary condition for motivation and that high levels of motivation were only possible, although not guaranteed, when at least a basic level of metacognition was present. The findings suggest that metacognition is a necessary building block for the development of motivation. Results suggest that targeting metacognition may be essential for improving motivation among people with schizophrenia spectrum disorders who do not meet this metacognition threshold.

  15. Cortisol responses on the dexamethasone suppression test among women with Bulimia-spectrum eating disorders: associations with clinical symptoms.

    Science.gov (United States)

    Bruce, Kenneth R; Steiger, Howard; Israël, Mimi; Groleau, Patricia; Ng Ying Kin, N M K; Ouellette, Anne-Sophie; Sycz, Lindsay; Badawi, Ghislaine

    2012-08-07

    Evidence associates Bulimia Nervosa (BN) with altered functioning of the hypothalamic-pituitary-adrenal (HPA) axis, but the clinical implications of such alterations need to be better understood. We contrasted cortisol responses to the dexamethasone suppression test (DST) in bulimic and non-eating disordered women and examined relationships among DST cortisol responses, eating symptoms and co-morbid disturbances. Sixty women with Bulimia Spectrum (BS) Disorders (either BN or normal weight Eating Disorder NOS with regular binge eating or purging) and 54 non-eating disordered women of similar age and body mass index participated in a 0.5 mg DST, and completed interviews and questionnaires assessing eating symptoms and co-morbid psychopathology. Compared with the normal-eater group, the BS women demonstrated significantly less DST suppression. Among BS women, DST non-suppression was associated with more severe depression, anxiety and eating preoccupations. Our findings show BS women to show less DST suppression compared to normal eater women, and results link extent of non-suppression, in BS individuals, to severity of depression, anxiety and eating preoccupations. Copyright © 2012 Elsevier Inc. All rights reserved.

  16. Preliminary study of family accommodation in youth with autism spectrum disorders and anxiety: Incidence, clinical correlates, and behavioral treatment response.

    Science.gov (United States)

    Storch, Eric A; Zavrou, Sophia; Collier, Amanda B; Ung, Danielle; Arnold, Elysse B; Mutch, P Jane; Lewin, Adam B; Murphy, Tanya K

    2015-08-01

    Anxiety symptoms are common in youth with autism spectrum disorders (ASD) and directly associated with symptom severity and functional impairment. Family accommodation occurs frequently among individuals with obsessive-compulsive and anxiety disorders; to date, no data exist on the nature and correlates of family accommodation in youth with ASD and anxiety, as well as its relationship to cognitive-behavioral therapy outcome. Forty children with ASD and a comorbid anxiety disorder participated. Clinicians administered measures of ASD and anxiety disorder caseness, anxiety symptom severity, and family accommodation; parents completed questionnaires assessing social responsiveness, internalizing and externalizing behaviors, and functional impairment. A subsample of youth (n = 24) completed a course of cognitive-behavioral therapy. Family accommodation was common and positively correlated with anxiety symptom severity, but not functional impairment, general internalizing symptoms, externalizing behavior, or social responsiveness. Family accommodation decreased following cognitive-behavioral therapy with decreases in family accommodation being associated with decreases in anxiety levels. Treatment responders reported lower family accommodation frequency and lower parent impact relative to non-responders. Clinical implications of this study in assessing and psychotherapeutically treating youth with ASD and comorbid anxiety are discussed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Cluster analysis of obsessive-compulsive spectrum disorders in patients with obsessive-compulsive disorder: clinical and genetic correlates.

    Science.gov (United States)

    Lochner, Christine; Hemmings, Sian M J; Kinnear, Craig J; Niehaus, Dana J H; Nel, Daniel G; Corfield, Valerie A; Moolman-Smook, Johanna C; Seedat, Soraya; Stein, Dan J

    2005-01-01

    Comorbidity of certain obsessive-compulsive spectrum disorders (OCSDs; such as Tourette's disorder) in obsessive-compulsive disorder (OCD) may serve to define important OCD subtypes characterized by differing phenomenology and neurobiological mechanisms. Comorbidity of the putative OCSDs in OCD has, however, not often been systematically investigated. The Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition , Axis I Disorders-Patient Version as well as a Structured Clinical Interview for Putative OCSDs (SCID-OCSD) were administered to 210 adult patients with OCD (N = 210, 102 men and 108 women; mean age, 35.7 +/- 13.3). A subset of Caucasian subjects (with OCD, n = 171; control subjects, n = 168), including subjects from the genetically homogeneous Afrikaner population (with OCD, n = 77; control subjects, n = 144), was genotyped for polymorphisms in genes involved in monoamine function. Because the items of the SCID-OCSD are binary (present/absent), a cluster analysis (Ward's method) using the items of SCID-OCSD was conducted. The association of identified clusters with demographic variables (age, gender), clinical variables (age of onset, obsessive-compulsive symptom severity and dimensions, level of insight, temperament/character, treatment response), and monoaminergic genotypes was examined. Cluster analysis of the OCSDs in our sample of patients with OCD identified 3 separate clusters at a 1.1 linkage distance level. The 3 clusters were named as follows: (1) "reward deficiency" (including trichotillomania, Tourette's disorder, pathological gambling, and hypersexual disorder), (2) "impulsivity" (including compulsive shopping, kleptomania, eating disorders, self-injury, and intermittent explosive disorder), and (3) "somatic" (including body dysmorphic disorder and hypochondriasis). Several significant associations were found between cluster scores and other variables; for example, cluster I scores were associated

  18. Mass spectrum analysis of serum biomarker proteins from patients with schizophrenia.

    Science.gov (United States)

    Zhou, Na; Wang, Jie; Yu, Yaqin; Shi, Jieping; Li, Xiaokun; Xu, Bin; Yu, Qiong

    2014-05-01

    Diagnosis of schizophrenia does not have a clear objective test at present, so we aimed to identify the potential biomarkers for the diagnosis of schizophrenia by comparison of serum protein profiling between first-episode schizophrenia patients and healthy controls. The combination of a magnetic bead separation system with matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometry (MALDI-TOF/TOF-MS) was used to analyze the serum protein spectra of 286 first-episode patients with schizophrenia, 41 chronic disease patients and 304 healthy controls. FlexAnlysis 3.0 and ClinProTools(TM) 2.1 software was used to establish a diagnostic model for schizophrenia. The results demonstrated that 10 fragmented peptides demonstrated an optimal discriminatory performance. Among these fragmented peptides, the peptide with m/z 1206.58 was identified as a fragment of fibrinopeptide A. Receiver operating characteristic analysis for m/z 1206.58 showed that the area under the curve was 0.981 for schizophrenia vs healthy controls, and 0.999 for schizophrenia vs other chronic disease controls. From our result, we consider that the analysis of serum protein spectrum using the magnetic bead separation system and MALDI-TOF/TOF-MS is an objective diagnostic tool. We conclude that fibrinopeptide A has the potential to be a biomarker for diagnosis of schizophrenia. This protein may also help to elucidate schizophrenia disease pathogenesis. Copyright © 2013 John Wiley & Sons, Ltd.

  19. 3D seismic data de-noising and reconstruction using Multichannel Time Slice Singular Spectrum Analysis

    Science.gov (United States)

    Rekapalli, Rajesh; Tiwari, R. K.; Sen, Mrinal K.; Vedanti, Nimisha

    2017-05-01

    Noises and data gaps complicate the seismic data processing and subsequently cause difficulties in the geological interpretation. We discuss a recent development and application of the Multi-channel Time Slice Singular Spectrum Analysis (MTSSSA) for 3D seismic data de-noising in time domain. In addition, L1 norm based simultaneous data gap filling of 3D seismic data using MTSSSA also discussed. We discriminated the noises from single individual time slices of 3D volumes by analyzing Eigen triplets of the trajectory matrix. We first tested the efficacy of the method on 3D synthetic seismic data contaminated with noise and then applied to the post stack seismic reflection data acquired from the Sleipner CO2 storage site (pre and post CO2 injection) from Norway. Our analysis suggests that the MTSSSA algorithm is efficient to enhance the S/N for better identification of amplitude anomalies along with simultaneous data gap filling. The bright spots identified in the de-noised data indicate upward migration of CO2 towards the top of the Utsira formation. The reflections identified applying MTSSSA to pre and post injection data correlate well with the geology of the Southern Viking Graben (SVG).

  20. Multichannel Singular Spectrum Analysis in the Estimates of Common Environmental Effects Affecting GPS Observations

    Science.gov (United States)

    Gruszczynska, Marta; Rosat, Severine; Klos, Anna; Gruszczynski, Maciej; Bogusz, Janusz

    2018-03-01

    We described a spatio-temporal analysis of environmental loading models: atmospheric, continental hydrology, and non-tidal ocean changes, based on multichannel singular spectrum analysis (MSSA). We extracted the common annual signal for 16 different sections related to climate zones: equatorial, arid, warm, snow, polar and continents. We used the loading models estimated for a set of 229 ITRF2014 (International Terrestrial Reference Frame) International GNSS Service (IGS) stations and discussed the amount of variance explained by individual modes, proving that the common annual signal accounts for 16, 24 and 68% of the total variance of non-tidal ocean, atmospheric and hydrological loading models, respectively. Having removed the common environmental MSSA seasonal curve from the corresponding GPS position time series, we found that the residual station-specific annual curve modelled with the least-squares estimation has the amplitude of maximum 2 mm. This means that the environmental loading models underestimate the seasonalities observed by the GPS system. The remaining signal present in the seasonal frequency band arises from the systematic errors which are not of common environmental or geophysical origin. Using common mode error (CME) estimates, we showed that the direct removal of environmental loading models from the GPS series causes an artificial loss in the CME power spectra between 10 and 80 cycles per year. When environmental effect is removed from GPS series with MSSA curves, no influence on the character of spectra of CME estimates was noticed.

  1. Adolescent boys with an autism spectrum disorder and their experience of sexuality : An interpretative phenomenological analysis

    NARCIS (Netherlands)

    Dewinter, J.; van Parys, H.; Vermeiren, R.; van Nieuwenhuizen, Ch.

    2017-01-01

    This qualitative study explored how adolescent boys with autism spectrum disorder experience their sexuality. Previous research has demonstrated that sexuality is a developmental task for boys with autism spectrum disorder, as it is for their peers. Case studies have suggested a relation between

  2. Modeling the relationship between photosynthetically active radiation and global horizontal irradiance using singular spectrum analysis

    International Nuclear Information System (INIS)

    Zempila, Melina-Maria; Taylor, Michael; Bais, Alkiviadis; Kazadzis, Stelios

    2016-01-01

    We report on the construction of generic models to calculate photosynthetically active radiation (PAR) from global horizontal irradiance (GHI), and vice versa. Our study took place at stations of the Greek UV network (UVNET) and the Hellenic solar energy network (HNSE) with measurements from NILU-UV multi-filter radiometers and CM pyranometers, chosen due to their long (≈1 M record/site) high temporal resolution (≈1 min) record that captures a broad range of atmospheric environments and cloudiness conditions. The uncertainty of the PAR measurements is quantified to be ±6.5% while the uncertainty involved in GHI measurements is up to ≈±7% according to the manufacturer. We show how multi-linear regression and nonlinear neural network (NN) models, trained at a calibration site (Thessaloniki) can be made generic provided that the input–output time series are processed with multi-channel singular spectrum analysis (M-SSA). Without M-SSA, both linear and nonlinear models perform well only locally. M-SSA with 50 time-lags is found to be sufficient for identification of trend, periodic and noise components in aerosol, cloud parameters and irradiance, and to construct regularized noise models of PAR from GHI irradiances. Reconstructed PAR and GHI time series capture ≈95% of the variance of the cross-validated target measurements and have median absolute percentage errors <2%. The intra-site median absolute error of M-SSA processed models were ≈8.2±1.7 W/m"2 for PAR and ≈9.2±4.2 W/m"2 for GHI. When applying the models trained at Thessaloniki to other stations, the average absolute mean bias between the model estimates and measured values was found to be ≈1.2 W/m"2 for PAR and ≈0.8 W/m"2 for GHI. For the models, percentage errors are well within the uncertainty of the measurements at all sites. Generic NN models were found to perform marginally better than their linear counterparts. - Highlights: • Generic linear regression and nonlinear neural network

  3. Cost-Effectiveness Analysis Comparing Pre-Diagnosis Autism Spectrum Disorder (ASD)-Targeted Intervention with Ontario's Autism Intervention Program

    Science.gov (United States)

    Penner, Melanie; Rayar, Meera; Bashir, Naazish; Roberts, S. Wendy; Hancock-Howard, Rebecca L.; Coyte, Peter C.

    2015-01-01

    Novel management strategies for autism spectrum disorder (ASD) propose providing interventions before diagnosis. We performed a cost-effectiveness analysis comparing the costs and dependency-free life years (DFLYs) generated by pre-diagnosis intensive Early Start Denver Model (ESDM-I); pre-diagnosis parent-delivered ESDM (ESDM-PD); and the Ontario…

  4. The Latent Structure of Autistic Traits: A Taxometric, Latent Class and Latent Profile Analysis of the Adult Autism Spectrum Quotient

    Science.gov (United States)

    James, Richard J.; Dubey, Indu; Smith, Danielle; Ropar, Danielle; Tunney, Richard J.

    2016-01-01

    Autistic traits are widely thought to operate along a continuum. A taxometric analysis of Adult Autism Spectrum Quotient data was conducted to test this assumption, finding little support but identifying a high severity taxon. To understand this further, latent class and latent profile models were estimated that indicated the presence of six…

  5. Parents' Experiences of Applied Behaviour Analysis (ABA)-Based Interventions for Children Diagnosed with Autistic Spectrum Disorder

    Science.gov (United States)

    McPhilemy, Catherine; Dillenburger, Karola

    2013-01-01

    Applied behaviour analysis (ABA)-based programmes are endorsed as the gold standard for treatment of children with autistic spectrum disorder (ASD) in most of North America. This is not the case in most of Europe, where instead a non-specified "eclectic" approach is adopted. We explored the social validity of ABA-based interventions with…

  6. Sum-rate analysis of spectrum sharing spatial multiplexing MIMO systems with zero-forcing and multiuser diversity

    KAUST Repository

    Yang, Liang; Qaraqe, Khalid A.; Serpedin, Erchin; Alouini, Mohamed-Slim

    2013-01-01

    This paper considers a multiuser spectrum sharing (SS) multiple-input multiple-output (MIMO) system with zero-forcing (ZF) operating in a Rayleigh fading environment. We provide an asymptotic sum-rate analysis to investigate the effects of different

  7. Maternal Diabetes and the Risk of Autism Spectrum Disorders in the Offspring: A Systematic Review and Meta-Analysis

    Science.gov (United States)

    Xu, Guifeng; Jing, Jin; Bowers, Katherine; Liu, Buyun; Bao, Wei

    2014-01-01

    We performed a systematic literature search regarding maternal diabetes before and during pregnancy and the risk of autism spectrum disorders (ASD) in the offspring. Of the 178 potentially relevant articles, 12 articles including three cohort studies and nine case-control studies were included in the meta-analysis. Both the meta-analyses of cohort…

  8. The Role of Theory of Mind on Social Information Processing in Children with Autism Spectrum Disorders: A Mediation Analysis

    Science.gov (United States)

    Mazza, Monica; Mariano, Melania; Peretti, Sara; Masedu, Francesco; Pino, Maria Chiara; Valenti, Marco

    2017-01-01

    Individuals with autism spectrum disorders (ASD) show significant impairments in social skills and theory of mind (ToM). The aim of this study was to evaluate ToM and social information processing abilities in 52 children with ASD compared to 55 typically developing (TD) children. A mediation analysis evaluated whether social information…

  9. Procedures and Compliance of a Video Modeling Applied Behavior Analysis Intervention for Brazilian Parents of Children with Autism Spectrum Disorders

    Science.gov (United States)

    Bagaiolo, Leila F.; Mari, Jair de J.; Bordini, Daniela; Ribeiro, Tatiane C.; Martone, Maria Carolina C.; Caetano, Sheila C.; Brunoni, Decio; Brentani, Helena; Paula, Cristiane S.

    2017-01-01

    Video modeling using applied behavior analysis techniques is one of the most promising and cost-effective ways to improve social skills for parents with autism spectrum disorder children. The main objectives were: (1) To elaborate/describe videos to improve eye contact and joint attention, and to decrease disruptive behaviors of autism spectrum…

  10. Array-CGH Analysis in a Cohort of Phenotypically Well-Characterized Individuals with "Essential" Autism Spectrum Disorders

    Science.gov (United States)

    Napoli, Eleonora; Russo, Serena; Casula, Laura; Alesi, Viola; Amendola, Filomena Alessandra; Angioni, Adriano; Novelli, Antonio; Valeri, Giovanni; Menghini, Deny; Vicari, Stefano

    2018-01-01

    Copy-number variants (CNVs) are associated with susceptibility to autism spectrum disorder (ASD). To detect the presence of CNVs, we conducted an array-comparative genomic hybridization (array-CGH) analysis in 133 children with "essential" ASD phenotype. Genetic analyses documented that 12 children had causative CNVs (C-CNVs), 29…

  11. Vibrational analysis of Fourier transform spectrum of the A3Π0–X1Σ ...

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 73; Issue 5. Vibrational analysis of Fourier transform spectrum of the A 3 0 – X 1 ∑ + and B 3 1 – X 1 ∑ + transitions of indium monobromide. Renu Singh K N Uttam M D Saksena M N Deo. Volume 73 Issue 5 November 2009 pp 889-899 ...

  12. Rotational Spectrum and Conformational Analysis of N-Methyl-2-Aminoethanol: Insights into the Shape of Adrenergic Neurotransmitters

    Directory of Open Access Journals (Sweden)

    Camilla Calabrese

    2018-02-01

    Full Text Available We describe an experimental and quantum chemical study for the accurate determination of the conformational space of small molecular systems governed by intramolecular non-covalent interactions. The model systems investigated belong to the biological relevant aminoalcohol's family, and include 2-amino-1-phenylethanol, 2-methylamino-1-phenylethanol, noradrenaline, adrenaline 2-aminoethanol, and N-methyl-2-aminoethanol. For the latter molecule, the rotational spectrum in the 6–18 and 59.6–74.4 GHz ranges was recorded in the isolated conditions of a free jet expansion. Based on the analysis of the rotational spectra, two different conformational species and 11 isotopologues were observed and their spectroscopic constants, including 14N-nuclear hyperfine coupling constants and methyl internal rotation barriers, were determined. From the experimental data a structural determination was performed, which was also used to benchmark accurate quantum chemical calculations on the whole conformational space. Atom in molecules and non-covalent interactions theories allowed the characterization of the position of the intramolecular non-covalent interactions and the energies involved, highlighting the subtle balance responsible of the stabilization of all the molecular systems.

  13. Abnormal Functional Connectivity of Resting State Network Detection Based on Linear ICA Analysis in Autism Spectrum Disorder.

    Science.gov (United States)

    Bi, Xia-An; Zhao, Junxia; Xu, Qian; Sun, Qi; Wang, Zhigang

    2018-01-01

    Some functional magnetic resonance imaging (fMRI) researches in autism spectrum disorder (ASD) patients have shown that ASD patients have significant impairment in brain response. However, few researchers have studied the functional structure changes of the eight resting state networks (RSNs) in ASD patients. Therefore, research on statistical differences of RSNs between 42 healthy controls (HC) and 50 ASD patients has been studied using linear independent component analysis (ICA) in this paper. Our researches showed that there was abnormal functional connectivity (FC) of RSNs in ASD patients. The RSNs with the decreased FC and increased FC in ASD patients included default mode network (DMN), central executive network (CEN), core network (CN), visual network (VN), self-referential network (SRN) compared to HC. The RSNs with the increased FC in ASD patients included auditory network (AN), somato-motor network (SMN). The dorsal attention network (DAN) in ASD patients showed the decreased FC. Our findings indicate that the abnormal FC in RSNs extensively exists in ASD patients. Our results have important contribution for the study of neuro-pathophysiological mechanisms in ASD patients.

  14. Rotational Spectrum and Conformational Analysis of N-methyl-2-aminoethanol: Insights into the Shape of Adrenergic Neurotransmitters

    Science.gov (United States)

    Calabrese, Camilla; Maris, Assimo; Evangelisti, Luca; Piras, Anna; Parravicini, Valentina; Melandri, Sonia

    2018-02-01

    Abstract We describe an experimental and quantum chemical study for the accurate determination of the conformational space of small molecular systems governed by intramolecular non-covalent interactions. The model systems investigated belong to the biological relevant aminoalcohol’s family, and include 2-aminophenylethanol, 2-methylaminophenylethanol, noradrenaline, adrenaline 2-aminoethanol and N-methyl-2-aminoethanol. For the latter molecule, the rotational spectrum in the 6-18 and 59.6-74.4 GHz ranges was recorded in the isolated conditions of a free jet expansion. Based on the analysis of the rotational spectra, two different conformational species and 11 isotopologues were observed and their spectroscopic constants, including 14N-nuclear hyperfine coupling constants and methyl internal rotation barriers, were determined. From the experimental data a structural determination was obtained, which was also used to benchmark accurate quantum chemical calculations on the whole conformational space. Atom in molecules and non-covalent interactions theories allowed the characterization of the position of the intramolecular non-covalent interactions and the energies involved, highlighting the subtle balance responsible of the stabilization of all the molecular systems.

  15. Portfolio and diversity analysis of energy technologies using full-spectrum risk measures

    Energy Technology Data Exchange (ETDEWEB)

    Jansen, J.C.; Beurskens, L.W.M. [ECN Policy Studies, Petten (Netherlands); Awerbuch, S.; Stirling, A.C. [Science and Technology Policy Research SPRU, University of Sussex, Brighton, East Sussex (United Kingdom)

    2005-01-01

    Energy diversity and security have been evaluated using the multi-criteria diversity analysis (MDA) of A. C. Stirling as well as more classical Markowitz mean-variance portfolio (MVP) theory. Each of these approaches is capable of producing an efficient frontier that shows optimal generating portfolio mixes, those that maximize performance (i.e. minimize cost) while minimizing risk or uncertainty (i.e. maximizing diversity). MDA covers the full-spectrum of uncertainty, reaching into areas where little is known about the range of possible outcomes, let alone their probabilities. However, MDA does not exploit statistical information that is available in certain parts of the risk-spectrum where historic means, variances and co-variances of outcomes are known and can be used to make inferences about the future. MVP operates precisely in this space. However, like other capital market models, its prescriptive value rests on the idea that the past is the best guide to the future. As such MVP can be blind to unforeseen events that create future structural change. Used in isolation, therefore, neither model offers a fully satisfying result. An MVP analysis of energy technologies tells us how to create generating portfolios with minimum cost and risk (cost-variance), assuming historic ranges predict the future well enough. If policy makers are confident that past expected values, ranges and variances will continue, then the solutions are fine. But what about so-called unknown risks? Possible future events that may produce outcomes with unknown consequences? This is where MDA becomes a potentially powerful tool. This project seeks to merge the two approaches and to map the space between optimal MVP and MDA solutions using a combined MVP+MDA optimization and weighting scheme. Placing 100% of the emphasis on MVP, for example, produces results based purely on historical trends. These may serve for short planning horizons. On the other hand, giving MDA a 100% weighting produces

  16. Additional Evidence Is Needed to Recommend Acquiring a Dog to Families of Children with Autism Spectrum Disorder: A Response to Wright and Colleagues

    Science.gov (United States)

    Crossman, Molly K.; Kazdin, Alan E.

    2016-01-01

    Caregivers of children with autism spectrum disorder are vulnerable to overstated benefits of interventions, and such overstatements are common with interventions involving animals. This response to Wright, Hall, Hames, Hardmin, Mills, the Paws Team, and Mills' (2015) article, "Acquiring a Pet Dog Significantly Reduces Stress of Primary…

  17. Increasing Opportunities for Question-Asking in School-Aged Children with Autism Spectrum Disorder: Effectiveness of Staff Training in Pivotal Response Treatment

    Science.gov (United States)

    Verschuur, Rianne; Huskens, Bibi; Verhoeven, Ludo; Didden, Robert

    2017-01-01

    Deficits in question-asking are common in children with autism spectrum disorder (ASD). Furthermore, their opportunities to self-initiate questions are often hindered by directive behavior of their conversation partners. This study assessed the effectiveness of staff training in pivotal response treatment (PRT) on staff member-created…

  18. The Effect of Pivotal Response Treatment in Children with Autism Spectrum Disorders: A Non-Randomized Study with a Blinded Outcome Measure

    Science.gov (United States)

    Duifhuis, E. A.; den Boer, J. C.; Doornbos, A.; Buitelaar, J. K.; Oosterling, I. J.; Klip, H.

    2017-01-01

    Purpose of this quasi-experimental trial was to investigate the effect of Pivotal response treatment (PRT) versus treatment as usual (TAU) on autism symptoms. Children with autism spectrum disorder (ASD), aged 3-8 years, received either PRT (n = 11) or TAU (n = 13). Primary outcome measure was the total score on the Autism Diagnostic Observation…

  19. The Effect of Pivotal Response Treatment in Children with Autism Spectrum Disorders: A Non-randomized Study with a Blinded Outcome Measure

    NARCIS (Netherlands)

    Duifhuis, E.A.; Boer, J.C. den; Doornbos, A.; Buitelaar, J.K.; Oosterling, I.J.; Klip, H.

    2017-01-01

    Purpose of this quasi-experimental trial was to investigate the effect of Pivotal response treatment (PRT) versus treatment as usual (TAU) on autism symptoms. Children with autism spectrum disorder (ASD), aged 3-8 years, received either PRT (n = 11) or TAU (n = 13). Primary outcome measure was the

  20. Perception of Life as Stressful, Not Biological Response to Stress, Is Associated with Greater Social Disability in Adults with Autism Spectrum Disorder

    Science.gov (United States)

    Bishop-Fitzpatrick, Lauren; Minshew, Nancy J.; Mazefsky, Carla A.; Eack, Shaun M.

    2017-01-01

    This study examined differences between adults with autism spectrum disorder (ASD; N = 40) and typical community volunteers (N = 25) on measures of stressful life events, perceived stress, and biological stress response (cardiovascular and cortisol reactivity) during a novel social stress task. Additional analyses examined the relationship between…

  1. Analysis of gait symmetry during over-ground walking in children with autism spectrum disorder.

    Science.gov (United States)

    Eggleston, Jeffrey D; Harry, John R; Hickman, Robbin A; Dufek, Janet S

    2017-06-01

    Gait symmetry is utilized as an indicator of neurologic function. Healthy gait often exhibits minimal asymmetries, while pathological gait exhibits exaggerated asymmetries. The purpose of this study was to examine symmetry of mechanical gait parameters during over-ground walking in children with Autism Spectrum Disorder (ASD). Kinematic and kinetic data were obtained from 10 children (aged 5-12 years) with ASD. The Model Statistic procedure (α=0.05) was used to compare gait related parameters between limbs. Analysis revealed children with ASD exhibit significant lower extremity joint position and ground reaction force asymmetries throughout the gait cycle. The observed asymmetries were unique for each subject. These data do not support previous research relative to gait symmetry in children with ASD. Many individuals with ASD do not receive physical therapy interventions, however, precision medicine based interventions emphasizing lower extremity asymmetries may improve gait function and improve performance during activities of daily living. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits.

    Science.gov (United States)

    Wong, C C Y; Meaburn, E L; Ronald, A; Price, T S; Jeffries, A R; Schalkwyk, L C; Plomin, R; Mill, J

    2014-04-01

    Autism spectrum disorder (ASD) defines a group of common, complex neurodevelopmental disorders. Although the aetiology of ASD has a strong genetic component, there is considerable monozygotic (MZ) twin discordance indicating a role for non-genetic factors. Because MZ twins share an identical DNA sequence, disease-discordant MZ twin pairs provide an ideal model for examining the contribution of environmentally driven epigenetic factors in disease. We performed a genome-wide analysis of DNA methylation in a sample of 50 MZ twin pairs (100 individuals) sampled from a representative population cohort that included twins discordant and concordant for ASD, ASD-associated traits and no autistic phenotype. Within-twin and between-group analyses identified numerous differentially methylated regions associated with ASD. In addition, we report significant correlations between DNA methylation and quantitatively measured autistic trait scores across our sample cohort. This study represents the first systematic epigenomic analyses of MZ twins discordant for ASD and implicates a role for altered DNA methylation in autism.

  3. Embedding Dimension Selection for Adaptive Singular Spectrum Analysis of EEG Signal

    Directory of Open Access Journals (Sweden)

    Shanzhi Xu

    2018-02-01

    Full Text Available The recorded electroencephalography (EEG signal is often contaminated with different kinds of artifacts and noise. Singular spectrum analysis (SSA is a powerful tool for extracting the brain rhythm from a noisy EEG signal. By analyzing the frequency characteristics of the reconstructed component (RC and the change rate in the trace of the Toeplitz matrix, it is demonstrated that the embedding dimension is related to the frequency bandwidth of each reconstructed component, in consistence with the component mixing in the singular value decomposition step. A method for selecting the embedding dimension is thereby proposed and verified by simulated EEG signal based on the Markov Process Amplitude (MPA EEG Model. Real EEG signal is also collected from the experimental subjects under both eyes-open and eyes-closed conditions. The experimental results show that based on the embedding dimension selection method, the alpha rhythm can be extracted from the real EEG signal by the adaptive SSA, which can be effectively utilized to distinguish between the eyes-open and eyes-closed states.

  4. Operator's guide for VAXGAP, a gamma-ray spectrum analysis package

    International Nuclear Information System (INIS)

    Killian, E.W.; Femec, D.A.

    1992-08-01

    This report describes the gamma-ray analysis program VAXGAP, which has continually evolved at the Idaho National Engineering Laboratory over a period of several years. It is an integrated suite of computer programs for performing analyses of pulse-height spectra from high-resolution gamma-ray spectrometers and assorted support functions. VAXGAP programs operate on Digital Equipment Corporation (DEC) VAX computers running the VMS operating system, and were written in VAX FORTRAN and DEC Digital Command Language (DCL). These programs make use of DEC GKS and ReGIS for graphical output on standard terminals and printers, and DEC windows for graphics on workstations and terminals that support the X Window System protocol. This report addresses the use of VAXGAP for data acquisition and control, energy scale calibration, and real-time analyses of background and sample pulse-height spectra. Also addressed are the creation and use efficiency tables and isotope libraries, manipulation of spectrum files and their contents, and graphical display of on-going acquisitions, saved spectra, and mathematical fits to spectral peaks

  5. Embedding Dimension Selection for Adaptive Singular Spectrum Analysis of EEG Signal.

    Science.gov (United States)

    Xu, Shanzhi; Hu, Hai; Ji, Linhong; Wang, Peng

    2018-02-26

    The recorded electroencephalography (EEG) signal is often contaminated with different kinds of artifacts and noise. Singular spectrum analysis (SSA) is a powerful tool for extracting the brain rhythm from a noisy EEG signal. By analyzing the frequency characteristics of the reconstructed component (RC) and the change rate in the trace of the Toeplitz matrix, it is demonstrated that the embedding dimension is related to the frequency bandwidth of each reconstructed component, in consistence with the component mixing in the singular value decomposition step. A method for selecting the embedding dimension is thereby proposed and verified by simulated EEG signal based on the Markov Process Amplitude (MPA) EEG Model. Real EEG signal is also collected from the experimental subjects under both eyes-open and eyes-closed conditions. The experimental results show that based on the embedding dimension selection method, the alpha rhythm can be extracted from the real EEG signal by the adaptive SSA, which can be effectively utilized to distinguish between the eyes-open and eyes-closed states.

  6. A Pilot Proteomic Analysis of Salivary Biomarkers in Autism Spectrum Disorder.

    Science.gov (United States)

    Ngounou Wetie, Armand G; Wormwood, Kelly L; Russell, Stefanie; Ryan, Jeanne P; Darie, Costel C; Woods, Alisa G

    2015-06-01

    Autism spectrum disorder (ASD) prevalence is increasing, with current estimates at 1/68-1/50 individuals diagnosed with an ASD. Diagnosis is based on behavioral assessments. Early diagnosis and intervention is known to greatly improve functional outcomes in people with ASD. Diagnosis, treatment monitoring and prognosis of ASD symptoms could be facilitated with biomarkers to complement behavioral assessments. Mass spectrometry (MS) based proteomics may help reveal biomarkers for ASD. In this pilot study, we have analyzed the salivary proteome in individuals with ASD compared to neurotypical control subjects, using MS-based proteomics. Our goal is to optimize methods for salivary proteomic biomarker discovery and to identify initial putative biomarkers in people with ASDs. The salivary proteome is virtually unstudied in ASD, and saliva could provide an easily accessible biomaterial for analysis. Using nano liquid chromatography-tandem mass spectrometry, we found statistically significant differences in several salivary proteins, including elevated prolactin-inducible protein, lactotransferrin, Ig kappa chain C region, Ig gamma-1 chain C region, Ig lambda-2 chain C regions, neutrophil elastase, polymeric immunoglobulin receptor and deleted in malignant brain tumors 1. Our results indicate that this is an effective method for identification of salivary protein biomarkers, support the concept that immune system and gastrointestinal disturbances may be present in individuals with ASDs and point toward the need for larger studies in behaviorally-characterized individuals. © 2015 International Society for Autism Research, Wiley Periodicals, Inc.

  7. A new methodology for fault detection in rolling element bearings using singular spectrum analysis

    Directory of Open Access Journals (Sweden)

    Bugharbee Hussein Al

    2018-01-01

    Full Text Available This paper proposes a vibration-based methodology for fault detection in rolling element bearings, which is based on pure data analysis via singular spectrum method. The method suggests building a baseline space from feature vectors made of the signals measured in the healthy/baseline bearing condition. The feature vectors are made using the Euclidean norms of the first three PC’s found for the signals measured. Then, the lagged version of any new signal corresponding to a new (possibly faulty condition is projected onto this baseline feature space in order to assess its similarity to the baseline condition. The category of a new signal vector is determined based on the Mahalanobis distance (MD of its feature vector to the baseline space. A validation of the methodology is suggested based on the results from an experimental test rig. The results obtained confirm the effective performance of the suggested methodology. It is made of simple steps and is easy to apply with a perspective to make it automatic and suitable for commercial applications.

  8. Quantitative analysis of disfluency in children with autism spectrum disorder or language impairment.

    Directory of Open Access Journals (Sweden)

    Heather MacFarlane

    Full Text Available Deficits in social communication, particularly pragmatic language, are characteristic of individuals with autism spectrum disorder (ASD. Speech disfluencies may serve pragmatic functions such as cueing speaking problems. Previous studies have found that speakers with ASD differ from typically developing (TD speakers in the types and patterns of disfluencies they produce, but fail to provide sufficiently detailed characterizations of the methods used to categorize and quantify disfluency, making cross-study comparison difficult. In this study we propose a simple schema for classifying major disfluency types, and use this schema in an exploratory analysis of differences in disfluency rates and patterns among children with ASD compared to TD and language impaired (SLI groups. 115 children ages 4-8 participated in the study (ASD = 51; SLI = 20; TD = 44, completing a battery of experimental tasks and assessments. Measures of morphological and syntactic complexity, as well as word and disfluency counts, were derived from transcripts of the Autism Diagnostic Observation Schedule (ADOS. High inter-annotator agreement was obtained with the use of the proposed schema. Analyses showed ASD children produced a higher ratio of content to filler disfluencies than TD children. Relative frequencies of repetitions, revisions, and false starts did not differ significantly between groups. TD children also produced more cued disfluencies than ASD children.

  9. Statistical Learning in Specific Language Impairment and Autism Spectrum Disorder: A Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Rita Obeid

    2016-08-01

    Full Text Available Impairments in statistical learning might be a common deficit among individuals with Specific Language Impairment (SLI and Autism Spectrum Disorder (ASD. Using meta-analysis, we examined statistical learning in SLI (14 studies, 15 comparisons and ASD (13 studies, 20 comparisons to evaluate this hypothesis. Effect sizes were examined as a function of diagnosis across multiple statistical learning tasks (Serial Reaction Time, Contextual Cueing, Artificial Grammar Learning, Speech Stream, Observational Learning, Probabilistic Classification. Individuals with SLI showed deficits in statistical learning relative to age-matched controls g = .47, 95% CI [.28, .66], p < .001. In contrast, statistical learning was intact in individuals with ASD relative to controls, g = –.13, 95% CI [–.34, .08], p = .22. Effect sizes did not vary as a function of task modality or participant age. Our findings inform debates about overlapping social-communicative difficulties in children with SLI and ASD by suggesting distinct underlying mechanisms. In line with the procedural deficit hypothesis (Ullman & Pierpont, 2005, impaired statistical learning may account for phonological and syntactic difficulties associated with SLI. In contrast, impaired statistical learning fails to account for the social-pragmatic difficulties associated with ASD.

  10. Using the Language Environment Analysis (LENA) system in preschool classrooms with children with autism spectrum disorders.

    Science.gov (United States)

    Dykstra, Jessica R; Sabatos-Devito, Maura G; Irvin, Dwight W; Boyd, Brian A; Hume, Kara A; Odom, Sam L

    2013-09-01

    This study describes the language environment of preschool programs serving children with autism spectrum disorders (ASDs) and examines relationships between child characteristics and an automated measure of adult and child language in the classroom. The Language Environment Analysis (LENA) system was used with 40 children with ASD to collect data on adult and child language. Standardized assessments were administered to obtain language, cognitive, and autism severity scores for participants. With a mean of over 5 hours of recording across two days several months apart, there was a mean of 3.6 child vocalizations per minute, 1.0 conversational turns (in which either the adult or child respond to the other within 5 seconds) per minute, and 29.2 adult words per minute. Two of the three LENA variables were significantly correlated with language age-equivalents. Cognitive age-equivalents were also significantly correlated with two LENA variables. Autism Diagnostic Observation Schedule severity scores and LENA variables were not significantly correlated. Implications for using the LENA system with children with ASD in the school environment are discussed.

  11. A theoretical analysis of the ultraviolet spectrum (180-260 nm) of pure liquid benzene

    International Nuclear Information System (INIS)

    Fernandez, M.; Tortajada, J.; Sese, L.M.

    1988-01-01

    This paper reports an attempt to understand theoretically the red shifts seen in the benzene ultraviolet spectrum upon changing from gas to the liquid phase. The theoretical analysis is performed through a framework which brings together Quantum Chemistry and Classical Statistical Mechanics of molecular liquids. As it is discussed herein, the influence of the liquid phase on the individual molecular properties is taken into account by means of a perturbation term included in the effective molecular Hamiltonian. Such a perturbation depends explicitly on both the chemical nature and the static structure of the liquid surrounding the molecule under study. In order to simulate the vibronic couplings, which make the benzene ''forbidden'' bands 1 L a and 1 L b have nonzero intensity, random displacements of the nuclei of benzene have been employed in this introductory work. The calculations involve the CNDO/S procedure and the atom-atom radial distribution functions of the liquid sample. The results account for the large red shift (≅ 20 nm) undergone by the band 1 L a . (orig.)

  12. GeneAnalytics Pathway Analysis and Genetic Overlap among Autism Spectrum Disorder, Bipolar Disorder and Schizophrenia

    Directory of Open Access Journals (Sweden)

    Naveen S. Khanzada

    2017-02-01

    Full Text Available Bipolar disorder (BPD and schizophrenia (SCH show similar neuropsychiatric behavioral disturbances, including impaired social interaction and communication, seen in autism spectrum disorder (ASD with multiple overlapping genetic and environmental influences implicated in risk and course of illness. GeneAnalytics software was used for pathway analysis and genetic profiling to characterize common susceptibility genes obtained from published lists for ASD (792 genes, BPD (290 genes and SCH (560 genes. Rank scores were derived from the number and nature of overlapping genes, gene-disease association, tissue specificity and gene functions subdivided into categories (e.g., diseases, tissues or functional pathways. Twenty-three genes were common to all three disorders and mapped to nine biological Superpathways including Circadian entrainment (10 genes, score = 37.0, Amphetamine addiction (five genes, score = 24.2, and Sudden infant death syndrome (six genes, score = 24.1. Brain tissues included the medulla oblongata (11 genes, score = 2.1, thalamus (10 genes, score = 2.0 and hypothalamus (nine genes, score = 2.0 with six common genes (BDNF, DRD2, CHRNA7, HTR2A, SLC6A3, and TPH2. Overlapping genes impacted dopamine and serotonin homeostasis and signal transduction pathways, impacting mood, behavior and physical activity level. Converging effects on pathways governing circadian rhythms support a core etiological relationship between neuropsychiatric illnesses and sleep disruption with hypoxia and central brain stem dysfunction.

  13. The performance of one belt and one road exchange rate: Based on improved singular spectrum analysis

    Science.gov (United States)

    Lai, Lin; Guo, Kun

    2017-10-01

    ;One Belt and One Road; strategy in China is on push of foreign trade openness at northwest, southwest and northeast, absorption of the excess capacity and new support for economic increase. However, the fluctuation in RMB exchange rate with the countries along the road is unstable so related Chinese enterprises will face high risk of exchange rate. Precise explanation or prediction for exchange rate has been the challengeable hop point in the international finance. This paper decomposed the One Belt One Road Exchange Rate Index (OBORR) and the RMB Effective Exchange Rate Index (CNYX) into trend term, market fluctuation term and noise term using improved singular spectrum analysis (SSA). It turns out that the increasing velocity of OBORR is greater than that of CNYX in the long term, and there is dynamic lead-lag structure in the medium term. In the short term, the fluctuation range and frequency of OBORR are greater than those of CNYX, which means there will be more exchange rate risks in One Belt and One Road countries.

  14. Daily rainfall forecasting for one year in a single run using Singular Spectrum Analysis

    Science.gov (United States)

    Unnikrishnan, Poornima; Jothiprakash, V.

    2018-06-01

    Effective modelling and prediction of smaller time step rainfall is reported to be very difficult owing to its highly erratic nature. Accurate forecast of daily rainfall for longer duration (multi time step) may be exceptionally helpful in the efficient planning and management of water resources systems. Identification of inherent patterns in a rainfall time series is also important for an effective water resources planning and management system. In the present study, Singular Spectrum Analysis (SSA) is utilized to forecast the daily rainfall time series pertaining to Koyna watershed in Maharashtra, India, for 365 days after extracting various components of the rainfall time series such as trend, periodic component, noise and cyclic component. In order to forecast the time series for longer time step (365 days-one window length), the signal and noise components of the time series are forecasted separately and then added together. The results of the study show that the method of SSA could extract the various components of the time series effectively and could also forecast the daily rainfall time series for longer duration such as one year in a single run with reasonable accuracy.

  15. Connectome-scale group-wise consistent resting-state network analysis in autism spectrum disorder

    Directory of Open Access Journals (Sweden)

    Yu Zhao

    2016-01-01

    Full Text Available Understanding the organizational architecture of human brain function and its alteration patterns in diseased brains such as Autism Spectrum Disorder (ASD patients are of great interests. In-vivo functional magnetic resonance imaging (fMRI offers a unique window to investigate the mechanism of brain function and to identify functional network components of the human brain. Previously, we have shown that multiple concurrent functional networks can be derived from fMRI signals using whole-brain sparse representation. Yet it is still an open question to derive group-wise consistent networks featured in ASD patients and controls. Here we proposed an effective volumetric network descriptor, named connectivity map, to compactly describe spatial patterns of brain network maps and implemented a fast framework in Apache Spark environment that can effectively identify group-wise consistent networks in big fMRI dataset. Our experiment results identified 144 group-wisely common intrinsic connectivity networks (ICNs shared between ASD patients and healthy control subjects, where some ICNs are substantially different between the two groups. Moreover, further analysis on the functional connectivity and spatial overlap between these 144 common ICNs reveals connectomics signatures characterizing ASD patients and controls. In particular, the computing time of our Spark-enabled functional connectomics framework is significantly reduced from 240 hours (C++ code, single core to 20 hours, exhibiting a great potential to handle fMRI big data in the future.

  16. Speech perception in autism spectrum disorder: An activation likelihood estimation meta-analysis.

    Science.gov (United States)

    Tryfon, Ana; Foster, Nicholas E V; Sharda, Megha; Hyde, Krista L

    2018-02-15

    Autism spectrum disorder (ASD) is often characterized by atypical language profiles and auditory and speech processing. These can contribute to aberrant language and social communication skills in ASD. The study of the neural basis of speech perception in ASD can serve as a potential neurobiological marker of ASD early on, but mixed results across studies renders it difficult to find a reliable neural characterization of speech processing in ASD. To this aim, the present study examined the functional neural basis of speech perception in ASD versus typical development (TD) using an activation likelihood estimation (ALE) meta-analysis of 18 qualifying studies. The present study included separate analyses for TD and ASD, which allowed us to examine patterns of within-group brain activation as well as both common and distinct patterns of brain activation across the ASD and TD groups. Overall, ASD and TD showed mostly common brain activation of speech processing in bilateral superior temporal gyrus (STG) and left inferior frontal gyrus (IFG). However, the results revealed trends for some distinct activation in the TD group showing additional activation in higher-order brain areas including left superior frontal gyrus (SFG), left medial frontal gyrus (MFG), and right IFG. These results provide a more reliable neural characterization of speech processing in ASD relative to previous single neuroimaging studies and motivate future work to investigate how these brain signatures relate to behavioral measures of speech processing in ASD. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Study of clay behaviour around a heat source by frequency spectrum analysis of seismic waves

    International Nuclear Information System (INIS)

    Sloovere, P. de.

    1993-01-01

    Wave propagated into soft rock is not completely described by purely linear elastic theory. Through spectrum analysis of wave, one can see that several frequencies are selected by the ground. ME2i uses this method to check grouting, piles a.s.o. The Mol experiment (on Radioactive Waste Disposal) aims to prove that little changes into heated clay can be detected by 'frequential seismic'. A cross-hole investigation system has been installed and tests have been performed for two years with a shear-hammer named MARGOT built to work inside horizontal boreholes: - Before heating the tests show the same results every time: . main frequency at 330 hertz; . maximal frequency at 520 hertz; - During heating: . the rays at 330 and 520 hertz disappear; . The frequencies in the range 100 - 300 hertz are prevailing; - After heating spectra have again their original shape. These results show that the effect is clear around an heated zone. The next steps should be: - Interpretation with computer's codes treating of wave propagation into a viscoelastic body; - Experimentations: . at the opening of a new gallery; . on big samples; . on granites and salt. 9 refs., 4 appendices

  18. Extended analysis and the ionization potential of the Ni III spectrum

    International Nuclear Information System (INIS)

    Garcia-Riquelme, O.; Rico, F.R.

    1992-01-01

    The Ni III spectrum emitted from a sliding spark in He, has been recorded in the UV 1300-1800A, on the 10.7m normal incidence vacuum spectrograph (plate factor 0.77A/mm), at the NIST in Washington. The low lying configurations 3d 7 4s, 3d 7 4p have been revised, new lines classified and the transitions 4p-4d, 4p-5s analyzed. The analysis has been extended to the spectral region up to 9000A and new terms from the electronic configurations 3d 7 5d, 6s, 5p, 4f and 5g have been identified. Theoretical Slater parametric calculations for these configurations and least square fits to the experimental levels have been performed. The ionization potential has been determined to 283 800±150cm -1 or 35.19±0.02eV. Table of new levels, the list of classified lines in the analyzed ranges 1300-1800, 2200-9000A, and the (LSF) parameters for the calculated configurations, are given. (orig.)

  19. Performance Analysis of Control Signal Transmission Technique for Cognitive Radios in Dynamic Spectrum Access Networks

    Science.gov (United States)

    Sakata, Ren; Tomioka, Tazuko; Kobayashi, Takahiro

    When cognitive radio (CR) systems dynamically use the frequency band, a control signal is necessary to indicate which carrier frequencies are currently available in the network. In order to keep efficient spectrum utilization, this control signal also should be transmitted based on the channel conditions. If transmitters dynamically select carrier frequencies, receivers have to receive control signals without knowledge of their carrier frequencies. To enable such transmission and reception, this paper proposes a novel scheme called DCPT (Differential Code Parallel Transmission). With DCPT, receivers can receive low-rate information with no knowledge of the carrier frequencies. The transmitter transmits two signals whose carrier frequencies are spaced by a predefined value. The absolute values of the carrier frequencies can be varied. When the receiver acquires the DCPT signal, it multiplies the signal by a frequency-shifted version of the signal; this yields a DC component that represents the data signal which is then demodulated. The performance was evaluated by means of numerical analysis and computer simulation. We confirmed that DCPT operates successfully even under severe interference if its parameters are appropriately configured.

  20. Detecting Abnormal Word Utterances in Children With Autism Spectrum Disorders: Machine-Learning-Based Voice Analysis Versus Speech Therapists.

    Science.gov (United States)

    Nakai, Yasushi; Takiguchi, Tetsuya; Matsui, Gakuyo; Yamaoka, Noriko; Takada, Satoshi

    2017-10-01

    Abnormal prosody is often evident in the voice intonations of individuals with autism spectrum disorders. We compared a machine-learning-based voice analysis with human hearing judgments made by 10 speech therapists for classifying children with autism spectrum disorders ( n = 30) and typical development ( n = 51). Using stimuli limited to single-word utterances, machine-learning-based voice analysis was superior to speech therapist judgments. There was a significantly higher true-positive than false-negative rate for machine-learning-based voice analysis but not for speech therapists. Results are discussed in terms of some artificiality of clinician judgments based on single-word utterances, and the objectivity machine-learning-based voice analysis adds to judging abnormal prosody.

  1. Calculation analysis of Wims/D4-Batan-2DIFF neutron spectrum on RSG-GAS with cadmium ratio

    International Nuclear Information System (INIS)

    Radianti, I.B.; Zuhair; Hamzah, A.

    1998-01-01

    The calculation analysis of WIMS/D4-BATAN-2DIFF neutron spectrum was performed by comparison the calculation result of cadmium ratio with the experiment result on CIP, IP2, IP3 and IP4 irradiation positions of RSG GAS tenth core. The foils of Au, Mn and Co were used for determination of the measured and calculated cadmium ratios. Spectrum calculation was done in 69 energy group with 541 energy group (till 10 MeV) cross section of foil absorption reaction. The difference values between cadmium ratio calculation and experiment result for all cases were in interval of 11.0%-26.3% which are out of measurement deviation range. From these result, it concluded that the use of WIM /D4 in generating group constant is not sufficient to obtain the neutron spectrum, especially for non-fuel region

  2. Accuracy evaluation of Fourier series analysis and singular spectrum analysis for predicting the volume of motorcycle sales in Indonesia

    Science.gov (United States)

    Sasmita, Yoga; Darmawan, Gumgum

    2017-08-01

    This research aims to evaluate the performance of forecasting by Fourier Series Analysis (FSA) and Singular Spectrum Analysis (SSA) which are more explorative and not requiring parametric assumption. Those methods are applied to predicting the volume of motorcycle sales in Indonesia from January 2005 to December 2016 (monthly). Both models are suitable for seasonal and trend component data. Technically, FSA defines time domain as the result of trend and seasonal component in different frequencies which is difficult to identify in the time domain analysis. With the hidden period is 2,918 ≈ 3 and significant model order is 3, FSA model is used to predict testing data. Meanwhile, SSA has two main processes, decomposition and reconstruction. SSA decomposes the time series data into different components. The reconstruction process starts with grouping the decomposition result based on similarity period of each component in trajectory matrix. With the optimum of window length (L = 53) and grouping effect (r = 4), SSA predicting testing data. Forecasting accuracy evaluation is done based on Mean Absolute Percentage Error (MAPE), Mean Absolute Error (MAE) and Root Mean Square Error (RMSE). The result shows that in the next 12 month, SSA has MAPE = 13.54 percent, MAE = 61,168.43 and RMSE = 75,244.92 and FSA has MAPE = 28.19 percent, MAE = 119,718.43 and RMSE = 142,511.17. Therefore, to predict volume of motorcycle sales in the next period should use SSA method which has better performance based on its accuracy.

  3. Procedures and compliance of a video modeling applied behavior analysis intervention for Brazilian parents of children with autism spectrum disorders.

    Science.gov (United States)

    Bagaiolo, Leila F; Mari, Jair de J; Bordini, Daniela; Ribeiro, Tatiane C; Martone, Maria Carolina C; Caetano, Sheila C; Brunoni, Decio; Brentani, Helena; Paula, Cristiane S

    2017-07-01

    Video modeling using applied behavior analysis techniques is one of the most promising and cost-effective ways to improve social skills for parents with autism spectrum disorder children. The main objectives were: (1) To elaborate/describe videos to improve eye contact and joint attention, and to decrease disruptive behaviors of autism spectrum disorder children, (2) to describe a low-cost parental training intervention, and (3) to assess participant's compliance. This is a descriptive study of a clinical trial for autism spectrum disorder children. The parental training intervention was delivered over 22 weeks based on video modeling. Parents with at least 8 years of schooling with an autism spectrum disorder child between 3 and 6 years old with an IQ lower than 70 were invited to participate. A total of 67 parents fulfilled the study criteria and were randomized into two groups: 34 as the intervention and 33 as controls. In all, 14 videos were recorded covering management of disruptive behaviors, prompting hierarchy, preference assessment, and acquisition of better eye contact and joint attention. Compliance varied as follows: good 32.4%, reasonable 38.2%, low 5.9%, and 23.5% with no compliance. Video modeling parental training seems a promising, feasible, and low-cost way to deliver care for children with autism spectrum disorder, particularly for populations with scarce treatment resources.

  4. Analysis of the fast-neutron spectrum inside the experimental cavity of the NRU Mk4 FN rod

    International Nuclear Information System (INIS)

    Leung, T.C.

    1995-01-01

    The fast-neutron (FN) rods in the NRU reactor provide a facility to study the effects of irradiation on CANDU reactor materials. The Mark 4 (Mk4) FN rods use natural uranium and supply fast-neutrons for experiments on irradiation creep and growth, and corrosion, for pressure- and calandria-tube materials. The neutron fluxes above 1 MeV are up to 2.7x10 17 n.m -2 .s -1 . This paper describes a calculation of the fast-neutron spectrum inside the NRU Mk4 FN rod cavity. The calculation was performed using the WIMS-AECL code, which is a multi-group transport code with two dimensional capabilities using the collision-probability method. Results for the fast-neutron spectrum above 1 MeV are presented in nine groups. The analysis confirms that the spectrum in the fast-neutron irradiation facility in NRU is representative of the actual irradiation spectrum for fast-neutron damage in a CANDU reactor. The effects of changes in specimen holder size, temperature, coolant density and fuel burnup on the fast neutron spectrum are also presented. (author). 9 refs., 3 tabs., 4 figs

  5. Power spectrum analysis of the x-ray scatter signal in mammography and breast tomosynthesis projections.

    Science.gov (United States)

    Sechopoulos, Ioannis; Bliznakova, Kristina; Fei, Baowei

    2013-10-01

    power spectrum reflected a fast drop-off with increasing spatial frequency, with a reduction of four orders of magnitude by 0.1 lp/mm. The β values for the scatter signal were 6.14 and 6.39 for the 0° and 30° projections, respectively. Although the low-frequency characteristics of scatter in mammography and breast tomosynthesis were known, a quantitative analysis of the frequency domain characteristics of this signal was needed in order to optimize previously proposed software-based x-ray scatter reduction algorithms for these imaging modalities.

  6. Measurement and analysis of noise power spectrum of computerized tomography in images

    International Nuclear Information System (INIS)

    Castro Tejero, P.; Garayoa Roca, J.

    2013-01-01

    This paper examines the implementation of the spectrum of powers of the noise, NPS, as metric to characterize the noise, both in magnitude and in texture, for CT scans. The NPS found show that you for convolution filters that assume a greater softening in the reconstructed image, spectrum is concentrated in the low frequencies, while for filters sharp, the spectrum extends to high frequencies. In the analyzed cases, there is a low frequency component, largely due to the structure-borne noise, which can be a potential negative effect on the detectability of injuries. (Author)

  7. Delayed P100-Like Latencies in Multiple Sclerosis: A Preliminary Investigation Using Visual Evoked Spread Spectrum Analysis

    Science.gov (United States)

    Kiiski, Hanni S. M.; Ní Riada, Sinéad; Lalor, Edmund C.; Gonçalves, Nuno R.; Nolan, Hugh; Whelan, Robert; Lonergan, Róisín; Kelly, Siobhán; O'Brien, Marie Claire; Kinsella, Katie; Bramham, Jessica; Burke, Teresa; Ó Donnchadha, Seán; Hutchinson, Michael; Tubridy, Niall; Reilly, Richard B.

    2016-01-01

    Conduction along the optic nerve is often slowed in multiple sclerosis (MS). This is typically assessed by measuring the latency of the P100 component of the Visual Evoked Potential (VEP) using electroencephalography. The Visual Evoked Spread Spectrum Analysis (VESPA) method, which involves modulating the contrast of a continuous visual stimulus over time, can produce a visually evoked response analogous to the P100 but with a higher signal-to-noise ratio and potentially higher sensitivity to individual differences in comparison to the VEP. The main objective of the study was to conduct a preliminary investigation into the utility of the VESPA method for probing and monitoring visual dysfunction in multiple sclerosis. The latencies and amplitudes of the P100-like VESPA component were compared between healthy controls and multiple sclerosis patients, and multiple sclerosis subgroups. The P100-like VESPA component activations were examined at baseline and over a 3-year period. The study included 43 multiple sclerosis patients (23 relapsing-remitting MS, 20 secondary-progressive MS) and 42 healthy controls who completed the VESPA at baseline. The follow-up sessions were conducted 12 months after baseline with 24 MS patients (15 relapsing-remitting MS, 9 secondary-progressive MS) and 23 controls, and again at 24 months post-baseline with 19 MS patients (13 relapsing-remitting MS, 6 secondary-progressive MS) and 14 controls. The results showed P100-like VESPA latencies to be delayed in multiple sclerosis compared to healthy controls over the 24-month period. Secondary-progressive MS patients had most pronounced delay in P100-like VESPA latency relative to relapsing-remitting MS and controls. There were no longitudinal P100-like VESPA response differences. These findings suggest that the VESPA method is a reproducible electrophysiological method that may have potential utility in the assessment of visual dysfunction in multiple sclerosis. PMID:26726800

  8. Delayed P100-Like Latencies in Multiple Sclerosis: A Preliminary Investigation Using Visual Evoked Spread Spectrum Analysis.

    Directory of Open Access Journals (Sweden)

    Hanni S M Kiiski

    Full Text Available Conduction along the optic nerve is often slowed in multiple sclerosis (MS. This is typically assessed by measuring the latency of the P100 component of the Visual Evoked Potential (VEP using electroencephalography. The Visual Evoked Spread Spectrum Analysis (VESPA method, which involves modulating the contrast of a continuous visual stimulus over time, can produce a visually evoked response analogous to the P100 but with a higher signal-to-noise ratio and potentially higher sensitivity to individual differences in comparison to the VEP. The main objective of the study was to conduct a preliminary investigation into the utility of the VESPA method for probing and monitoring visual dysfunction in multiple sclerosis. The latencies and amplitudes of the P100-like VESPA component were compared between healthy controls and multiple sclerosis patients, and multiple sclerosis subgroups. The P100-like VESPA component activations were examined at baseline and over a 3-year period. The study included 43 multiple sclerosis patients (23 relapsing-remitting MS, 20 secondary-progressive MS and 42 healthy controls who completed the VESPA at baseline. The follow-up sessions were conducted 12 months after baseline with 24 MS patients (15 relapsing-remitting MS, 9 secondary-progressive MS and 23 controls, and again at 24 months post-baseline with 19 MS patients (13 relapsing-remitting MS, 6 secondary-progressive MS and 14 controls. The results showed P100-like VESPA latencies to be delayed in multiple sclerosis compared to healthy controls over the 24-month period. Secondary-progressive MS patients had most pronounced delay in P100-like VESPA latency relative to relapsing-remitting MS and controls. There were no longitudinal P100-like VESPA response differences. These findings suggest that the VESPA method is a reproducible electrophysiological method that may have potential utility in the assessment of visual dysfunction in multiple sclerosis.

  9. Effects of Combining Medication and Pivotal Response Treatment on Aberrant Behavior in Children with Autism Spectrum Disorder

    Directory of Open Access Journals (Sweden)

    Mohammad Rezaei

    2018-01-01

    Full Text Available Abstract: The purpose of this study was to investigate the effects of combined risperidone (RIS and pivotal response treatment (PRT on children with autism spectrum disorder (ASD. A total of 34 children diagnosed with ASD according to the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-V (mean age of 12.36 years were randomly assigned to either of two groups; the first group (n = 17 received combined PRT–RIS while the second group (n = 17 received RIS only. Behavioral problems were evaluated with the Aberrant Behavior Checklist (ABC, whereas global improvement (GI was measured with the Clinical Global Impressions (CGI. Assessment of ABC was performed before intervention, after intervention (12 weeks, and following 3 months of the intervention (follow-up. Total ABC scores were seen to decrease in both groups after 3 months, as compared with the scores prior to the interventions. Also, in both groups, mean scores of behavioral problems after the intervention were not significantly different from those prior to the intervention, in all subscales but the inappropriate speech (p < 0.001. However, both groups showed significant differences in mean scores of ABC subscales in both of the post-intervention evaluation stages. It was concluded that the combination of behavioral and drug interventions can further improve behavioral problems, ultimately improving patient’s communication and social skills.

  10. Sleep problems in children with autism spectrum disorder: examining the contributions of sensory over-responsivity and anxiety.

    Science.gov (United States)

    Mazurek, Micah O; Petroski, Gregory F

    2015-02-01

    Children with autism spectrum disorder (ASD) are at high risk for sleep problems. Previous research suggests that sensory problems and anxiety may be related to the development and maintenance of sleep problems in children with ASD. However, the relationships among these co-occurring conditions have not been previously studied. The current study examined the interrelations of these symptoms in a large well-characterized sample of children and adolescents with ASD. The current study examined the relationships among sleep problems, sensory over-responsivity, and anxiety in 1347 children enrolled in the Autism Speaks Autism Treatment Network. The primary measures included the Children's Sleep Habits Questionnaire, the Child Behavior Checklist, and the Short Sensory Profile. In bivariate correlations and multivariate path analyses, anxiety was associated with all types of sleep problems (ie, bedtime resistance, sleep-onset delay, sleep duration, sleep anxiety, and night wakings; p children, while SOR was no longer significantly associated with bedtime resistance or sleep anxiety for younger children. Children with ASD who have anxiety and SOR may be particularly predisposed to sleep problems. These findings suggest that some children with ASD and sleep disturbance may have difficulties with hyperarousal. Future research using physiological measures of arousal and objective measures of sleep are needed. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. Linkage between pain sensitivity and empathic response in adolescents with autism spectrum conditions and conduct disorder symptoms.

    Science.gov (United States)

    Chen, Chenyi; Hung, An-Yi; Fan, Yang-Teng; Tan, Shuai; Hong, Hua; Cheng, Yawei

    2017-02-01

    Lack of empathy is one of the behavioral hallmarks in individuals with autism spectrum conditions (ASC) as well as youth with conduct disorder symptoms (CDS). Previous research has reliably documented considerable overlap between the perception of others' pain and first-hand experience of pain. However, the linkage between empathy for pain and sensitivity to physical pain needs to be empirically determined, particularly in individuals with empathy deficits. This study measured the pressure pain threshold, which indexes sensitization of peripheral nociceptors, and assessed subjective ratings of unpleasantness and pain intensity in response to empathy-eliciting stimuli depicting physical bodily injuries in three age- and sex-matched participant groups: ASC, CDS, and typically developing controls (TDC). The results indicated that the pain threshold was lowest in the ASC group and highest in the CDS group. The ASC group displayed lower ratings of unpleasantness and pain intensity than did the TDC and CDS groups. Within the ASC and CDS, pain intensity ratings were significantly correlated with unpleasantness ratings to others' pain. Moreover, the ASC significantly differed from the TDC in the correlation between pain threshold values and unpleasantness ratings. These findings may cast some light on the linkage between atypical low-level sensory functioning, for instance altered pain sensitivity, and high-level empathic processing. Autism Res 2017, 10: 267-275. © 2016 International Society for Autism Research, Wiley Periodicals, Inc. © 2016 International Society for Autism Research, Wiley Periodicals, Inc.

  12. Children with autism spectrum disorders show abnormal conditioned response timing on delay, but not trace, eyeblink conditioning

    Science.gov (United States)

    Oristaglio, Jeff; West, Susan Hyman; Ghaffari, Manely; Lech, Melissa S.; Verma, Beeta R.; Harvey, John A.; Welsh, John P.; Malone, Richard P.

    2013-01-01

    Children with autism spectrum disorder (ASD) and age-matched typically-developing (TD) peers were tested on two forms of eyeblink conditioning (EBC), a Pavlovian associative learning paradigm where subjects learn to execute an appropriately-timed eyeblink in response to a previously neutral conditioning stimulus (CS). One version of the task, trace EBC, interposes a stimulus-free interval between the presentation of the CS and the unconditioned stimulus (US), a puff of air to the eye which causes subjects to blink. In delay EBC, the CS overlaps in time with the delivery of the US, usually with both stimuli terminating simultaneously. ASD children performed normally during trace EBC, exhibiting no differences from typically-developing (TD) subjects with regard to learning rate or the timing of the CR. However, when subsequently tested on delay EBC, subjects with ASD displayed abnormally-timed conditioned eye blinks that began earlier and peaked sooner than those of TD subjects, consistent with previous findings. The results suggest an impaired ability of children with ASD to properly time conditioned eye blinks which appears to be specific to delay EBC. We suggest that this deficit may reflect a dysfunction of cerebellar cortex in which increases in the intensity or duration of sensory input can temporarily disrupt the accuracy of motor timing over short temporal intervals. PMID:23769889

  13. Use of local noise power spectrum and wavelet analysis in quantitative image quality assurance for EPIDs

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Soyoung [Department of Radiation Oncology, University Hospitals Case and Medical Center, Cleveland, Ohio 44106 (United States); Yan, Guanghua; Bassett, Philip; Samant, Sanjiv, E-mail: samant@ufl.edu [Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida 32608 (United States); Gopal, Arun [Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, Maryland 21201 (United States)

    2016-09-15

    Purpose: To investigate the use of local noise power spectrum (NPS) to characterize image noise and wavelet analysis to isolate defective pixels and inter-subpanel flat-fielding artifacts for quantitative quality assurance (QA) of electronic portal imaging devices (EPIDs). Methods: A total of 93 image sets including custom-made bar-pattern images and open exposure images were collected from four iViewGT a-Si EPID systems over three years. Global quantitative metrics such as modulation transform function (MTF), NPS, and detective quantum efficiency (DQE) were computed for each image set. Local NPS was also calculated for individual subpanels by sampling region of interests within each subpanel of the EPID. The 1D NPS, obtained by radially averaging the 2D NPS, was fitted to a power-law function. The r-square value of the linear regression analysis was used as a singular metric to characterize the noise properties of individual subpanels of the EPID. The sensitivity of the local NPS was first compared with the global quantitative metrics using historical image sets. It was then compared with two commonly used commercial QA systems with images collected after applying two different EPID calibration methods (single-level gain and multilevel gain). To detect isolated defective pixels and inter-subpanel flat-fielding artifacts, Haar wavelet transform was applied on the images. Results: Global quantitative metrics including MTF, NPS, and DQE showed little change over the period of data collection. On the contrary, a strong correlation between the local NPS (r-square values) and the variation of the EPID noise condition was observed. The local NPS analysis indicated image quality improvement with the r-square values increased from 0.80 ± 0.03 (before calibration) to 0.85 ± 0.03 (after single-level gain calibration) and to 0.96 ± 0.03 (after multilevel gain calibration), while the commercial QA systems failed to distinguish the image quality improvement between the two

  14. Deficits in response inhibition correlate with oculomotor control in children with fetal alcohol spectrum disorder and prenatal alcohol exposure.

    Science.gov (United States)

    Paolozza, Angelina; Rasmussen, Carmen; Pei, Jacqueline; Hanlon-Dearman, Ana; Nikkel, Sarah M; Andrew, Gail; McFarlane, Audrey; Samdup, Dawa; Reynolds, James N

    2014-02-01

    Children with fetal alcohol spectrum disorder (FASD) or prenatal alcohol exposure (PAE) frequently exhibit impairment on tasks measuring inhibition. The objective of this study was to determine if a performance-based relationship exists between psychometric tests and eye movement tasks in children with FASD. Participants for this dataset were aged 5-17 years and included those diagnosed with an FASD (n=72), those with PAE but no clinical FASD diagnosis (n=21), and typically developing controls (n=139). Participants completed a neurobehavioral test battery, which included the NEPSY-II subtests of auditory attention, response set, and inhibition. Each participant completed a series of saccadic eye movement tasks, which included the antisaccade and memory-guided tasks. Both the FASD and the PAE groups performed worse than controls on the subtest measures of attention and inhibition. Compared with controls, the FASD group made more errors on the antisaccade and memory-guided tasks. Among the combined FASD/PAE group, inhibition and switching errors were negatively correlated with direction errors on the antisaccade task but not on the memory-guided task. There were no significant correlations in the control group. These data suggests that response inhibition deficits in children with FASD/PAE are associated with difficulty controlling saccadic eye movements which may point to overlapping brain regions damaged by prenatal alcohol exposure. The results of this study demonstrate that eye movement control tasks directly relate to outcome measures obtained with psychometric tests that are used during FASD diagnosis, and may therefore help with early identification of children who would benefit from a multidisciplinary diagnostic assessment. Copyright © 2013 Elsevier B.V. All rights reserved.

  15. Integrated analysis of whole-exome sequencing and transcriptome profiling in males with autism spectrum disorders.

    Science.gov (United States)

    Codina-Solà, Marta; Rodríguez-Santiago, Benjamín; Homs, Aïda; Santoyo, Javier; Rigau, Maria; Aznar-Laín, Gemma; Del Campo, Miguel; Gener, Blanca; Gabau, Elisabeth; Botella, María Pilar; Gutiérrez-Arumí, Armand; Antiñolo, Guillermo; Pérez-Jurado, Luis Alberto; Cuscó, Ivon

    2015-01-01

    Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders with high heritability. Recent findings support a highly heterogeneous and complex genetic etiology including rare de novo and inherited mutations or chromosomal rearrangements as well as double or multiple hits. We performed whole-exome sequencing (WES) and blood cell transcriptome by RNAseq in a subset of male patients with idiopathic ASD (n = 36) in order to identify causative genes, transcriptomic alterations, and susceptibility variants. We detected likely monogenic causes in seven cases: five de novo (SCN2A, MED13L, KCNV1, CUL3, and PTEN) and two inherited X-linked variants (MAOA and CDKL5). Transcriptomic analyses allowed the identification of intronic causative mutations missed by the usual filtering of WES and revealed functional consequences of some rare mutations. These included aberrant transcripts (PTEN, POLR3C), deregulated expression in 1.7% of mutated genes (that is, SEMA6B, MECP2, ANK3, CREBBP), allele-specific expression (FUS, MTOR, TAF1C), and non-sense-mediated decay (RIT1, ALG9). The analysis of rare inherited variants showed enrichment in relevant pathways such as the PI3K-Akt signaling and the axon guidance. Integrative analysis of WES and blood RNAseq data has proven to be an efficient strategy to identify likely monogenic forms of ASD (19% in our cohort), as well as additional rare inherited mutations that can contribute to ASD risk in a multifactorial manner. Blood transcriptomic data, besides validating 88% of expressed variants, allowed the identification of missed intronic mutations and revealed functional correlations of genetic variants, including changes in splicing, expression levels, and allelic expression.

  16. Anatomical likelihood estimation meta-analysis of grey and white matter anomalies in autism spectrum disorders

    Directory of Open Access Journals (Sweden)

    Thomas P. DeRamus

    2015-01-01

    Full Text Available Autism spectrum disorders (ASD are characterized by impairments in social communication and restrictive, repetitive behaviors. While behavioral symptoms are well-documented, investigations into the neurobiological underpinnings of ASD have not resulted in firm biomarkers. Variability in findings across structural neuroimaging studies has contributed to difficulty in reliably characterizing the brain morphology of individuals with ASD. These inconsistencies may also arise from the heterogeneity of ASD, and wider age-range of participants included in MRI studies and in previous meta-analyses. To address this, the current study used coordinate-based anatomical likelihood estimation (ALE analysis of 21 voxel-based morphometry (VBM studies examining high-functioning individuals with ASD, resulting in a meta-analysis of 1055 participants (506 ASD, and 549 typically developing individuals. Results consisted of grey, white, and global differences in cortical matter between the groups. Modeled anatomical maps consisting of concentration, thickness, and volume metrics of grey and white matter revealed clusters suggesting age-related decreases in grey and white matter in parietal and inferior temporal regions of the brain in ASD, and age-related increases in grey matter in frontal and anterior-temporal regions. White matter alterations included fiber tracts thought to play key roles in information processing and sensory integration. Many current theories of pathobiology ASD suggest that the brains of individuals with ASD may have less-functional long-range (anterior-to-posterior connections. Our findings of decreased cortical matter in parietal–temporal and occipital regions, and thickening in frontal cortices in older adults with ASD may entail altered cortical anatomy, and neurodevelopmental adaptations.

  17. K, L, and M shell datasets for PIXE spectrum fitting and analysis

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, David D., E-mail: dcz@ansto.gov.au; Crawford, Jagoda; Siegele, Rainer

    2015-11-15

    Highlights: • Differences between several datasets commonly used by PIXE codes for spectrum fitting and concentration estimates have been highlighted. • A preferred option dataset was selected which includes ionisation cross sections, fluorescence yield, Coster–Kronig probabilities and X-ray line emission rates for K, L and M subshells. • For PIXE codes differences of several tens of percent can be seen for selected elements for L and M lines depending on the data sets selected. - Abstract: Routine PIXE analysis programs, like GUPIX, GEOPIXE and PIXAN generally perform at least two key functions firstly, the fitting of K, L and M characteristic lines X-ray lines to a background, including unfolding of overlapping lines and secondly, the use of a fitted primary Kα, Lα or Mα line area to determine the elemental concentration in a given matrix. To achieve these two results to better than 3–5% the data sets for fluorescence yields, emission rates, Coster–Kronig transitions and ionisation cross sections should be determined to better than 3%. There are many different theoretical and experimental K, L and M datasets for these parameters. How they are applied and used in analysis programs can vary the results obtained for both fitting and concentration determinations. Here we discuss several commonly used datasets for fluorescence yields, emission rates, Coster–Kronig transitions and ionisation cross sections for K, L and M subshells and suggests an optimum set to obtain consistent results for PIXE analyses across a range of elements with atomic numbers from 5 ⩽ Z ⩽ 100.

  18. Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification.

    Science.gov (United States)

    De Brouwer, Sara; De Preter, Katleen; Kumps, Candy; Zabrocki, Piotr; Porcu, Michaël; Westerhout, Ellen M; Lakeman, Arjan; Vandesompele, Jo; Hoebeeck, Jasmien; Van Maerken, Tom; De Paepe, Anne; Laureys, Geneviève; Schulte, Johannes H; Schramm, Alexander; Van Den Broecke, Caroline; Vermeulen, Joëlle; Van Roy, Nadine; Beiske, Klaus; Renard, Marleen; Noguera, Rosa; Delattre, Olivier; Janoueix-Lerosey, Isabelle; Kogner, Per; Martinsson, Tommy; Nakagawara, Akira; Ohira, Miki; Caron, Huib; Eggert, Angelika; Cools, Jan; Versteeg, Rogier; Speleman, Frank

    2010-09-01

    Activating mutations of the anaplastic lymphoma kinase (ALK) were recently described in neuroblastoma. We carried out a meta-analysis of 709 neuroblastoma tumors to determine their frequency and mutation spectrum in relation to genomic and clinical parameters, and studied the prognostic significance of ALK copy number and expression. The frequency and type of ALK mutations, copy number gain, and expression were analyzed in a new series of 254 neuroblastoma tumors. Data from 455 published cases were used for further in-depth analysis. ALK mutations were present in 6.9% of 709 investigated tumors, and mutations were found in similar frequencies in favorable [International Neuroblastoma Staging System (INSS) 1, 2, and 4S; 5.7%] and unfavorable (INSS 3 and 4; 7.5%) neuroblastomas (P = 0.087). Two hotspot mutations, at positions R1275 and F1174, were observed (49% and 34.7% of the mutated cases, respectively). Interestingly, the F1174 mutations occurred in a high proportion of MYCN-amplified cases (P = 0.001), and this combined occurrence was associated with a particular poor outcome, suggesting a positive cooperative effect between both aberrations. Furthermore, the F1174L mutant was characterized by a higher degree of autophosphorylation and a more potent transforming capacity as compared with the R1275Q mutant. Chromosome 2p gains, including the ALK locus (91.8%), were associated with a significantly increased ALK expression, which was also correlated with poor survival. ALK mutations occur in equal frequencies across all genomic subtypes, but F1174L mutants are observed in a higher frequency of MYCN-amplified tumors and show increased transforming capacity as compared with the R1275Q mutants.

  19. A Virtual Joy-Stick Study of Emotional Responses and Social Motivation in Children with Autism Spectrum Disorder

    Science.gov (United States)

    Kim, Kwanguk; Rosenthal, Zachary; Gwaltney, Mary; Jarrold, William; Lerro, Lindsay; Mundy, Peter

    2015-01-01

    A new virtual reality task was employed which uses preference for interpersonal distance to social stimuli to examine social motivation and emotion perception in children with Autism Spectrum Disorders. Nineteen children with higher functioning Autism Spectrum Disorder (HFA SD) and 23 age, gender, and IQ matched children with typical development…

  20. Brief Report: The Autism Spectrum Quotient Has Convergent Validity with the Social Responsiveness Scale in a High-Functioning Sample

    Science.gov (United States)

    Armstrong, Kimberly; Iarocci, Grace

    2013-01-01

    The Autism Spectrum Quotient (AQ) is widely used to measure autism spectrum disorder (ASD) symptoms and screen for ASD. It is readily available free of charge online and is easily accessible to practitioners, researchers and individuals who suspect that they may have an ASD. Thus, the AQ is a potentially useful, widely accessible tool for ASD…

  1. Gene-set analysis shows association between FMRP targets and autism spectrum disorder

    NARCIS (Netherlands)

    Jansen, Arija; Dieleman, Gwen C; Smit, August B; Verhage, Matthijs; Verhulst, Frank C; Polderman, Tinca J C; Posthuma, Danielle

    Autism spectrum disorder (ASD) is a heterogeneous group of disorders characterized by problems with social interaction, communication, and repetitive and restricted behavior. Despite its high heritability and the substantial progress made in elucidating genetic associations, the corresponding

  2. Comparative analysis of three screening instruments for autism spectrum disorder in toddlers at high risk.

    NARCIS (Netherlands)

    Oosterling, I.J.; Swinkels, S.H.N.; Gaag, R.J. van der; Visser, J.C.; Dietz, C.; Buitelaar, J.K.

    2009-01-01

    Several instruments have been developed to screen for autism spectrum disorders (ASD) in high-risk populations. However, few studies compare different instruments in one sample. Data were gathered from the Early Screening of Autistic Traits Questionnaire, Social Communication Questionnaire,

  3. Analysis of the photon spectrum in inclusive B --> X$_{s}\\gamma$ decays

    CERN Document Server

    Neubert, M

    1994-01-01

    Using a combination of the operator product and heavy quark expansions we resum the leading nonperturbative contributions to the inclusive photon spectrum in $B\\to X_s\\,\\gamma$ decays. The shape of the spectrum is determined by a structure function, which describes the distribution of the light-cone momentum fraction of the $b$-quark inside the $B$ meson. The moments of the spectrum are proportional to forward matrix elements of higher-dimension operators. As a byproduct, we obtain the bound $\\lambda_1<0$ for one of the fundamental parameters of the heavy quark effective theory. The integral over the $B\\to X_s\\,\\gamma$ structure function is related to the shape function that governs the fall-off of the lepton spectrum close to the endpoint in $B\\to X_u\\,\\ell\\,\\bar\

  4. Performance analysis of spectrum sensing with multiple status changes in primary user traffic

    KAUST Repository

    Tang, Liang; Chen, Yunfei; Hines, Evor L.; Alouini, Mohamed-Slim

    2012-01-01

    In this letter, the impact of primary user traffic with multiple status changes on the spectrum sensing performance is analyzed. Closed-form expressions for the probabilities of false alarm and detection are derived. Numerical results show

  5. Analysis of technology and business antecedents for spectrum sharing in mobile broadband networks

    OpenAIRE

    Yrjölä, S. (Seppo)

    2017-01-01

    Abstract Sharing is emerging as one of the megatrends influencing future business opportunities, and wireless communications is no exception to this development. Future mobile broadband networks will operate on different types of spectrum bands including shared spectrum, which calls for changes in the operation and management of the networks. The creation and capture of value by the different players in the mobile broadband ecosystem is expected to change due to regulation, technology, an...

  6. Analysis Framework for Opportunistic Spectrum OFDMA and its Application to the IEEE 802.22 Standard

    OpenAIRE

    Park, Jihoon; Pawełczak, Przemysław; Grønsund, Pål; Čabrić, Danijela

    2010-01-01

    We present an analytical model that enables throughput evaluation of Opportunistic Spectrum Orthogonal Frequency Division Multiple Access (OS-OFDMA) networks. The core feature of the model, based on a discrete time Markov chain, is the consideration of different channel and subchannel allocation strategies under different Primary and Secondary user types, traffic and priority levels. The analytical model also assesses the impact of different spectrum sensing strategies on the throughput of OS...

  7. Using near infrared spectrum analysis to predict water and chlorophyll content in tomato leaves

    Science.gov (United States)

    Jiang, Huanyu; Ying, Yibin; Liu, Yande

    2004-11-01

    In this study, we developed a nondestructive way to analyze water and chlorophyll content in tomato leaves. A total of 200 leaves were collected as experimental materials, 120 of them were used to form a calibration data set. Drying chest, SPAD meter and NIR spectrometer were used to get water content, chlorophyll content and spectrums of tomato leaves respectively. The Fourier Transform Infrared (FTNIR) method with a smart Near-IR Updrift was used to test spectrums, and partial least squares (PLS) technique was used to analyze the data we get by normal experimentation and near infrared spectrometer, set up a calibration model to predict the leaf water and chlorophyll content based on the characteristics of diffuse reflectance spectrums of tomato leaves. Three different mathematical treatments were used in spectrums processing: different wavelength range, different smoothing points, first and second derivative. We can get best prediction model when we select full range (800-2500nm), 3 points for spectrums smoothing and spectrums by baseline correction, the best model of chlorophyll content has a root mean square error of prediction (RMSEP) of 8.16 and a calibration correlation coefficient (R2) value of 0.89452 and the best model of water content has a root mean square error of prediction (RMSEP) of 0.0214 and a calibration correlation coefficient (R2) value of 0.91043.

  8. A novel power harmonic analysis method based on Nuttall-Kaiser combination window double spectrum interpolated FFT algorithm

    Science.gov (United States)

    Jin, Tao; Chen, Yiyang; Flesch, Rodolfo C. C.

    2017-11-01

    Harmonics pose a great threat to safe and economical operation of power grids. Therefore, it is critical to detect harmonic parameters accurately to design harmonic compensation equipment. The fast Fourier transform (FFT) is widely used for electrical popular power harmonics analysis. However, the barrier effect produced by the algorithm itself and spectrum leakage caused by asynchronous sampling often affects the harmonic analysis accuracy. This paper examines a new approach for harmonic analysis based on deducing the modifier formulas of frequency, phase angle, and amplitude, utilizing the Nuttall-Kaiser window double spectrum line interpolation method, which overcomes the shortcomings in traditional FFT harmonic calculations. The proposed approach is verified numerically and experimentally to be accurate and reliable.

  9. Item Response Data Analysis Using Stata Item Response Theory Package

    Science.gov (United States)

    Yang, Ji Seung; Zheng, Xiaying

    2018-01-01

    The purpose of this article is to introduce and review the capability and performance of the Stata item response theory (IRT) package that is available from Stata v.14, 2015. Using a simulated data set and a publicly available item response data set extracted from Programme of International Student Assessment, we review the IRT package from…

  10. Neural responses to affective and cognitive theory of mind in children and adolescents with autism spectrum disorder.

    Science.gov (United States)

    Kim, Eunjoo; Kyeong, Sunghyon; Cheon, Keun-Ah; Park, Bumhee; Oh, Maeng-Keun; Chun, Ji Won; Park, Hae-Jeong; Kim, Jae-Jin; Song, Dong-Ho

    2016-05-16

    Children and adolescents with Autism Spectrum Disorder (ASD) are characterized by an impaired Theory of Mind (ToM). Recent evidence suggested that two aspects of ToM (cognitive ToM versus affective ToM) are differentially impaired in individuals with ASD. In this study, we examined the neural correlates of cognitive and affective ToM in children and adolescents with ASD compared to typically developing children (TDCs). Twelve children and adolescents with ASD and 12 age, IQ matched TDCs participated in this functional MRI study. The ToM task involved the attribution of cognitive and affective mental states to a cartoon character based on verbal and eye-gaze cues. In cognitive ToM tasks, ASD participants recruited the medial prefrontal cortex (mPFC), anterior cingulate cortex (ACC), and superior temporal gyrus (STG) to a greater extent than did TDCs. In affective ToM tasks, both ASD and TDC participants showed more activation in the insula and other subcortical regions than in cognitive ToM tasks. Correlational analysis revealed that greater activation of the mPFC/ACC regions was associated with less symptom severity in ASD patients. In sum, our study suggests that the recruitment of additional prefrontal resources can compensate for the successful behavioral performance in the ToM task in ASD participants. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  11. TLR4 response mediates ethanol-induced neurodevelopment alterations in a model of fetal alcohol spectrum disorders.

    Science.gov (United States)

    Pascual, María; Montesinos, Jorge; Montagud-Romero, Sandra; Forteza, Jerónimo; Rodríguez-Arias, Marta; Miñarro, José; Guerri, Consuelo

    2017-07-24

    Inflammation during brain development participates in the pathogenesis of early brain injury and cognitive dysfunctions. Prenatal ethanol exposure affects the developing brain and causes neural impairment, cognitive and behavioral effects, collectively known as fetal alcohol spectrum disorders (FASD). Our previous studies demonstrate that ethanol activates the innate immune response and TLR4 receptor and causes neuroinflammation, brain damage, and cognitive defects in the developmental brain stage of adolescents. We hypothesize that by activating the TLR4 response, maternal alcohol consumption during pregnancy triggers the release of cytokines and chemokines in both the maternal sera and brains of fetuses/offspring, which impairs brain ontogeny and causes cognitive dysfunction. WT and TLR4-KO female mice treated with or without 10% ethanol in the drinking water during gestation and lactation were used. Cytokine/chemokine levels were determined by ELISA in the amniotic fluid, maternal serum, and cerebral cortex, as well as in the offspring cerebral cortex. Microglial and neuronal markers (evaluated by western blotting), myelin proteins (immunohistochemical and western blotting) and synaptic parameters (western blotting and electron microscopy) were assessed in the cortices of the WT and TLR4-KO pups on PND 0, 20, and 66. Behavioral tests (elevated plus maze and passive avoidance) were performed in the WT and TLR4-KO mice on PND 66 exposed or not to ethanol. We show that alcohol intake during gestation and lactation increases the levels of several cytokines/chemokines (IL-1β, IL-17, MIP-1α, and fractalkine) in the maternal sera, amniotic fluid, and brains of fetuses and offspring. The upregulation of cytokines/chemokines is associated with an increase in activated microglia markers (CD11b and MHC-II), and with a reduction in some synaptic (synaptotagmin, synapsin IIa) and myelin (MBP, PLP) proteins in the brains of offspring on days 0, 20, and 66 (long-term effects

  12. EVALUASI SIMPANGAN STRUKTUR AKIBAT PENAMBAHAN LANTAI DENGAN METODE ANALISIS STATIK DAN DINAMIK RESPONSE SPECTRUM (Studi Kasus : Pembangunan Gedung Dekanat Fakultas Teknik UNTIRTA

    Directory of Open Access Journals (Sweden)

    Soelarso Soelarso

    2017-07-01

    Full Text Available The Advancement of Science and Technology made Indonesians increasingly concerned about education at the university so that the increasing of students must be balanced with the development of education building infrastructure. In 2015, have been built 3 floors which functioned as offices for Dean Faculty of Engineering Untirta, but in the process of implementation is done re-design with the addition of 3 floors above it to meet space requirement at the Faculty of Engineering Untirta. This research was conducted to re-analyze the deflection of structure building in order to know the deflection of structures due to the addition of load and the effect of earthquake force, so that can be evaluated to plan the addition of floor as much as 3 floors in Faculty of Engineering Untirta building structure. The analytical method used are the equivalent static analysis and dynamic response spectrum analysis using the computer program Extended Three dimensional Analysis Building System (ETABS. Resulted from 3D model analysis with the addition of 3 floors, the behavior of structures in the modes 1,2 and 3 respectively happened translations X direction, Y direction and Z axis rotation. Base shear force that occurred for 1.549.45 kN at X direction and 1.581,06 kN at Y direction. Maximum deflection that happened at 298,65 mm due to earthquake load X direction, 249,59 mm due to earthquake load Y direction. The deflection value has exceeded the allowable deflection limit of 186 mm, so that the existing structures cannot resist against the working load  due to the addition of the floor according to the design standard of SNI 03-1726-2012.

  13. A framework for noise-power spectrum analysis of multidimensional images

    International Nuclear Information System (INIS)

    Siewerdsen, J.H.; Cunningham, I.A.; Jaffray, D.A.

    2002-01-01

    A methodological framework for experimental analysis of the noise-power spectrum (NPS) of multidimensional images is presented that employs well-known properties of the n-dimensional (nD) Fourier transform. The approach is generalized to n dimensions, reducing to familiar cases for n=1 (e.g., time series) and n=2 (e.g., projection radiography) and demonstrated experimentally for two cases in which n=3 (viz., using an active matrix flat-panel imager for x-ray fluoroscopy and cone-beam CT to form three-dimensional (3D) images in spatiotemporal and volumetric domains, respectively). The relationship between fully nD NPS analysis and various techniques for analyzing a 'central slice' of the NPS is formulated in a manner that is directly applicable to measured nD data, highlights the effects of correlation, and renders issues of NPS normalization transparent. The spatiotemporal NPS of fluoroscopic images is analyzed under varying conditions of temporal correlation (image lag) to investigate the degree to which the NPS is reduced by such correlation. For first-frame image lag of ∼5-8 %, the NPS is reduced by ∼20% compared to the lag-free case. A simple model is presented that results in an approximate rule of thumb for computing the effect of image lag on NPS under conditions of spatiotemporal separability. The volumetric NPS of cone-beam CT images is analyzed under varying conditions of spatial correlation, controlled by adjustment of the reconstruction filter. The volumetric NPS is found to be highly asymmetric, exhibiting a ramp characteristic in transverse planes (typical of filtered back-projection) and a band-limited characteristic in the longitudinal direction (resulting from low-pass characteristics of the imager). Such asymmetry could have implications regarding the detectability of structures visualized in transverse versus sagittal or coronal planes. In all cases, appreciation of the full dimensionality of the image data is essential to obtaining

  14. Spatial and radiometric characterization of multi-spectrum satellite images through multi-fractal analysis

    Science.gov (United States)

    Alonso, Carmelo; Tarquis, Ana M.; Zúñiga, Ignacio; Benito, Rosa M.

    2017-03-01

    Several studies have shown that vegetation indexes can be used to estimate root zone soil moisture. Earth surface images, obtained by high-resolution satellites, presently give a lot of information on these indexes, based on the data of several wavelengths. Because of the potential capacity for systematic observations at various scales, remote sensing technology extends the possible data archives from the present time to several decades back. Because of this advantage, enormous efforts have been made by researchers and application specialists to delineate vegetation indexes from local scale to global scale by applying remote sensing imagery. In this work, four band images have been considered, which are involved in these vegetation indexes, and were taken by satellites Ikonos-2 and Landsat-7 of the same geographic location, to study the effect of both spatial (pixel size) and radiometric (number of bits coding the image) resolution on these wavelength bands as well as two vegetation indexes: the Normalized Difference Vegetation Index (NDVI) and the Enhanced Vegetation Index (EVI). In order to do so, a multi-fractal analysis of these multi-spectral images was applied in each of these bands and the two indexes derived. The results showed that spatial resolution has a similar scaling effect in the four bands, but radiometric resolution has a larger influence in blue and green bands than in red and near-infrared bands. The NDVI showed a higher sensitivity to the radiometric resolution than EVI. Both were equally affected by the spatial resolution. From both factors, the spatial resolution has a major impact in the multi-fractal spectrum for all the bands and the vegetation indexes. This information should be taken in to account when vegetation indexes based on different satellite sensors are obtained.

  15. The radio recombination line spectrum of Orion A: Observations and analysis

    International Nuclear Information System (INIS)

    Lockman, F.J.; Brown, R.L.

    1975-01-01

    The entire body of radio observations of Orion A has been considered, and the means by which the temperature and density can be derived from the ratio T/subL//T/subC/ and the line width Δv of the hydrogen radio recombination lines is examined. Since it is critical to determine the extent to which low-frequency line measurements are contaminated by ''baseline-subtraction'' problems, new observations are presented which, together with general considerations of the line shape and data reduction processes, support the following conclusions: T/subL//T/subC/ and Δv can be accurately determined in the low-frequency observations even when erroneous baselines are removed; in accord with other studies, a density gradient must exist in the nebula; isothermal models cannot reproduce the observed line strenghts; the most dense parts of the nebula must be somewhat cooler than the surrounding gas. A model of Orion A has been constructed that is derived directly from the radio continuum observations. These observations demand that the simplest possible model of the nebula be comprised of three regions whose gross properties: the electrons density and the size: are defined by the continuum measurements. This model has been used for an analysis of the radio recombination line data, and virtually all known radio data on the Orion Nebula including Δv and T/subL//T/subC/ of the H nα lines from 610 MHz to 85 GHz Δv and T/subL//T/subC/ of all the observed H nβ lines; the shape and magnitude of the radio continuum spectrum can be reproduced. The application of this model to the problem of the abundance and distribution of ionized helium with the nebula is also considered

  16. Histological spectrum of angiofibroma of soft tissue: histological and genetic analysis of 13 cases.

    Science.gov (United States)

    Yamada, Yuichi; Yamamoto, Hidetaka; Kohashi, Kenichi; Ishii, Takeaki; Iura, Kunio; Maekawa, Akira; Bekki, Hirofumi; Otsuka, Hiroshi; Yamashita, Kyoko; Tanaka, Hiroyuki; Hiraki, Tsubasa; Mukai, Munenori; Shirakawa, Atsuko; Shinnou, Yoko; Jinno, Mari; Yanai, Hiroyuki; Taguchi, Kenichi; Maehara, Yoshihiko; Iwamoto, Yukihide; Oda, Yosinao

    2016-09-01

    Angiofibroma of soft tissue (AFST) is a rare soft tissue neoplasm characterized by a fibroblastic cytomorphology and a prominent vascular structure. AFSTs possess a novel fusion gene, i.e. NCOA2-AHRR/AHRR-NCOA2 or GTF2I-NCOA2, providing a useful approach to diagnosing AFST. Morphologically, AFSTs span a wide spectrum, making diagnosis a challenge. The aim of this study was to review AFST cases and to report previously unknown histological features, which we confirmed by genetic analysis. We reviewed 276 cases diagnosed as solitary fibrous tumours/haemangiopericytomas (232 cases), unclassified tumours of fibroblastic differentiation (36 cases), and recently diagnosed AFSTs (eight cases), and retrieved 13 cases compatible with AFST. Immunohistochemical staining was performed for these cases, all 13 of which were analysed by reverse transcription polymerase chain reaction and fluorescence in-situ hybridization. The histological findings were as follows: amianthoid fibres, extravasation of red blood cells, haemosiderin deposition, aggregates of foamy histiocytes, cystic change, necrosis, and haemorrhage. Immunohistochemically, the tumour cells were positive for epithelial membrane antigen (four of 13 cases), desmin (six of 13 cases), CD163 (13 of 13 cases), CD68 (seven of 13 cases), oestrogen receptor (13 of 13 cases), progesterone receptor (three of 13 cases), and STAT6 (one of 13 cases, weak nuclear staining), but they were negative for CD34, α-smooth muscle actin, muscle-specific actin, S100, pan-cytokeratin, MDM2, and CDK4. The AHRR-NCOA2 fusion gene was detected in eight cases, and NCOA2 gene rearrangement in nine cases. We revealed the previously unreported histological variation and immunohistochemical findings of AFST, and confirmed them by using genetic methods. The results suggested that AFST should be considered in the diagnosis of fibrous or fibrohistiocytic tumours with the above histological features. © 2016 John Wiley & Sons Ltd.

  17. Autism spectrum disorders and schizophrenia: meta-analysis of the neural correlates of social cognition.

    Directory of Open Access Journals (Sweden)

    Gisela Sugranyes

    Full Text Available CONTEXT: Impaired social cognition is a cardinal feature of Autism Spectrum Disorders (ASD and Schizophrenia (SZ. However, the functional neuroanatomy of social cognition in either disorder remains unclear due to variability in primary literature. Additionally, it is not known whether deficits in ASD and SZ arise from similar or disease-specific disruption of the social cognition network. OBJECTIVE: To identify regions most robustly implicated in social cognition processing in SZ and ASD. DATA SOURCES: Systematic review of English language articles using MEDLINE (1995-2010 and reference lists. STUDY SELECTION: Studies were required to use fMRI to compare ASD or SZ subjects to a matched healthy control group, provide coordinates in standard stereotactic space, and employ standardized facial emotion recognition (FER or theory of mind (TOM paradigms. DATA EXTRACTION: Activation foci from studies meeting inclusion criteria (n = 33 were subjected to a quantitative voxel-based meta-analysis using activation likelihood estimation, and encompassed 146 subjects with ASD, 336 SZ patients and 492 healthy controls. RESULTS: Both SZ and ASD showed medial prefrontal hypoactivation, which was more pronounced in ASD, while ventrolateral prefrontal dysfunction was associated mostly with SZ. Amygdala hypoactivation was observed in SZ patients during FER and in ASD during more complex ToM tasks. Both disorders were associated with hypoactivation within the Superior Temporal Sulcus (STS during ToM tasks, but activation in these regions was increased in ASD during affect processing. Disease-specific differences were noted in somatosensory engagement, which was increased in SZ and decreased in ASD. Reduced thalamic activation was uniquely seen in SZ. CONCLUSIONS: Reduced frontolimbic and STS engagement emerged as a shared feature of social cognition deficits in SZ and ASD. However, there were disease- and stimulus-specific differences. These findings may aid future

  18. Capturing the spectrum of interaction effects in genetic association studies by simulated evaporative cooling network analysis.

    Directory of Open Access Journals (Sweden)

    Brett A McKinney

    2009-03-01

    Full Text Available Evidence from human genetic studies of several disorders suggests that interactions between alleles at multiple genes play an important role in influencing phenotypic expression. Analytical methods for identifying Mendelian disease genes are not appropriate when applied to common multigenic diseases, because such methods investigate association with the phenotype only one genetic locus at a time. New strategies are needed that can capture the spectrum of genetic effects, from Mendelian to multifactorial epistasis. Random Forests (RF and Relief-F are two powerful machine-learning methods that have been studied as filters for genetic case-control data due to their ability to account for the context of alleles at multiple genes when scoring the relevance of individual genetic variants to the phenotype. However, when variants interact strongly, the independence assumption of RF in the tree node-splitting criterion leads to diminished importance scores for relevant variants. Relief-F, on the other hand, was designed to detect strong interactions but is sensitive to large backgrounds of variants that are irrelevant to classification of the phenotype, which is an acute problem in genome-wide association studies. To overcome the weaknesses of these data mining approaches, we develop Evaporative Cooling (EC feature selection, a flexible machine learning method that can integrate multiple importance scores while removing irrelevant genetic variants. To characterize detailed interactions, we construct a genetic-association interaction network (GAIN, whose edges quantify the synergy between variants with respect to the phenotype. We use simulation analysis to show that EC is able to identify a wide range of interaction effects in genetic association data. We apply the EC filter to a smallpox vaccine cohort study of single nucleotide polymorphisms (SNPs and infer a GAIN for a collection of SNPs associated with adverse events. Our results suggest an important

  19. Applied behavior analysis: behavior management of children with autism spectrum disorders in dental environments.

    Science.gov (United States)

    Hernandez, Purnima; Ikkanda, Zachary

    2011-03-01

    There are a limited number of studies addressing behavior management techniques and procedural modifications that dentists can use to treat people with an autism spectrum disorder (ASD). The authors conducted a search of the dental and behavioral analytic literature to identify management techniques that address problem behaviors exhibited by children with ASDs in dental and other health-related environments. Applied behavior analysis (ABA) is a science in which procedures are based on the principles of behavior through systematic experimentation. Clinicians have used ABA procedures successfully to modify socially significant behaviors of people with ASD. Basic behavior management techniques currently used in dentistry may not encourage people with cognitive and behavioral disabilities, such as ASD, to tolerate simple in-office dental procedures consistently. Instead, dental care providers often are required to use advanced behavior management techniques to complete simple in-office procedures such as prophylaxis, sealant placement and obtaining radiographs. ABA procedures can be integrated in the dental environment to manage problem behaviors often exhibited by children with an ASD. The authors found no evidence-based procedural modifications that address the behavioral characteristics and problematic behaviors of children with an ASD in a dental environment. Further research in this area should be conducted. Knowledge and in-depth understanding of behavioral principles is essential when a dentist is concerned with modifying behaviors. Using ABA procedures can help dentists manage problem behaviors effectively and systematically when performing routine dental treatment. Being knowledgeable about each patient's behavioral characteristics and the parents' level of involvement is important in the successful integration of the procedures and reduction of in-office time.

  20. Statistical Analysis of Zebrafish Locomotor Response.

    Science.gov (United States)

    Liu, Yiwen; Carmer, Robert; Zhang, Gaonan; Venkatraman, Prahatha; Brown, Skye Ashton; Pang, Chi-Pui; Zhang, Mingzhi; Ma, Ping; Leung, Yuk Fai

    2015-01-01

    Zebrafish larvae display rich locomotor behaviour upon external stimulation. The movement can be simultaneously tracked from many larvae arranged in multi-well plates. The resulting time-series locomotor data have been used to reveal new insights into neurobiology and pharmacology. However, the data are of large scale, and the corresponding locomotor behavior is affected by multiple factors. These issues pose a statistical challenge for comparing larval activities. To address this gap, this study has analyzed a visually-driven locomotor behaviour named the visual motor response (VMR) by the Hotelling's T-squared test. This test is congruent with comparing locomotor profiles from a time period. Different wild-type (WT) strains were compared using the test, which shows that they responded differently to light change at different developmental stages. The performance of this test was evaluated by a power analysis, which shows that the test was sensitive for detecting differences between experimental groups with sample numbers that were commonly used in various studies. In addition, this study investigated the effects of various factors that might affect the VMR by multivariate analysis of variance (MANOVA). The results indicate that the larval activity was generally affected by stage, light stimulus, their interaction, and location in the plate. Nonetheless, different factors affected larval activity differently over time, as indicated by a dynamical analysis of the activity at each second. Intriguingly, this analysis also shows that biological and technical repeats had negligible effect on larval activity. This finding is consistent with that from the Hotelling's T-squared test, and suggests that experimental repeats can be combined to enhance statistical power. Together, these investigations have established a statistical framework for analyzing VMR data, a framework that should be generally applicable to other locomotor data with similar structure.

  1. Global approach of emergency response, reflection analysis

    International Nuclear Information System (INIS)

    Velasco Garcia, E.; Garcia Ahumada, F.; Albaladejo Vidal, S.

    1998-01-01

    The emergency response management approach must be dealt with adequately within company strategy, since a badly managed emergency situation can adversely affect a company, not only in terms of asset, but also in terms of the negative impact on its credibility, profitability and image. Thereby, it can be said that there are three main supports to manage the response in an emergency situation. a) Diagnosis b) Prognosis. c) Communications. To reach these capabilities it is necessary a co-ordination of different actions at the following levels. i. Facility Operation implies Local level. ii. Facility Property implies National level iii. Local Authority implies Local level iv. National Authority implies National level Taking into account all the last, these following functions must be covered: a) Management: incorporating communication, diagnosis and prognosis areas. b) Decision: incorporating communication and information means. c) Services: in order to facilitate the decision, as well as the execution of this decision. d) Analysis: in order to facilitate the situations that make easier to decide. e) Documentation: to seek the information for the analysts and decision makers. (Author)

  2. Response approach to the squeezed-limit bispectrum: application to the correlation of quasar and Lyman-α forest power spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Chiang, Chi-Ting [C.N. Yang Institute for Theoretical Physics, Stony Brook University, Stony Brook, NY 11794 (United States); Cieplak, Agnieszka M.; Slosar, Anže [Brookhaven National Laboratory, Blgd 510, Upton, NY 11375 (United States); Schmidt, Fabian, E-mail: chi-ting.chiang@stonybrook.edu, E-mail: acieplak@bnl.gov, E-mail: fabians@mpa-garching.mpg.de, E-mail: anze@bnl.gov [Max-Planck-Institut für Astrophysik, Karl-Schwarzschild-Str. 1, 85741 Garching (Germany)

    2017-06-01

    The squeezed-limit bispectrum, which is generated by nonlinear gravitational evolution as well as inflationary physics, measures the correlation of three wavenumbers, in the configuration where one wavenumber is much smaller than the other two. Since the squeezed-limit bispectrum encodes the impact of a large-scale fluctuation on the small-scale power spectrum, it can be understood as how the small-scale power spectrum ''responds'' to the large-scale fluctuation. Viewed in this way, the squeezed-limit bispectrum can be calculated using the response approach even in the cases which do not submit to perturbative treatment. To illustrate this point, we apply this approach to the cross-correlation between the large-scale quasar density field and small-scale Lyman-α forest flux power spectrum. In particular, using separate universe simulations which implement changes in the large-scale density, velocity gradient, and primordial power spectrum amplitude, we measure how the Lyman-α forest flux power spectrum responds to the local, long-wavelength quasar overdensity, and equivalently their squeezed-limit bispectrum. We perform a Fisher forecast for the ability of future experiments to constrain local non-Gaussianity using the bispectrum of quasars and the Lyman-α forest. Combining with quasar and Lyman-α forest power spectra to constrain the biases, we find that for DESI the expected 1−σ constraint is err[ f {sub NL}]∼60. Ability for DESI to measure f {sub NL} through this channel is limited primarily by the aliasing and instrumental noise of the Lyman-α forest flux power spectrum. The combination of response approach and separate universe simulations provides a novel technique to explore the constraints from the squeezed-limit bispectrum between different observables.

  3. Measurement and analysis of reaction rate distributions of cores with spectrum shifter region

    International Nuclear Information System (INIS)

    Matsuura, Shigekazu; Shiroya, Seiji; Unesaki, Hironobu; Takeda, Toshikazu; Aizawa, Otohiko; Kanda, Keiji.

    1995-01-01

    A study for the neutronic characteristics of the spectrum-controlled neutron irradiation fields using various reflector materials was performed. Spectrum shifter regions were constructed in the upper reflector region of the solid moderated core (B-Core) of the Kyoto University Critical Assembly (KUCA). Beryllium, graphite and aluminum were selected as the loading materials for the spectrum shifter. Two tight-pitch lattice cores with different moderator-to-fuel volume ratio (V m /V f ) of 0.97 and 0.65 have been used. Axial reaction rate distributions of gold, nickel and indium wires were measured, and the spectrum index was defined as the Cd ratio of the gold wire and the ratio of gold reaction rate to nickel reaction rate. Using the conventional design calculation procedure, the experimental and calculated reaction rate and spectrum index show several disagreements. Detailed treatment of the neutron streaming effect, heterogeneous cell structure and depression factor are shown to be necessary for improving the agreement between experimental and calculated values. (author)

  4. Early sensory over-responsivity in toddlers with autism spectrum disorders as a predictor of family impairment and parenting stress.

    Science.gov (United States)

    Ben-Sasson, A; Soto, T W; Martínez-Pedraza, F; Carter, A S

    2013-08-01

    Sensory over-responsivity (SOR) affects many individuals with autism spectrum disorders (ASD), often leading to stressful encounters during daily routines. This study describes the associations between early SOR symptoms and the longitudinal course of restrictions in family life activities and parenting stress across three time-points in families raising a child with ASD (n = 174). Covariates were child diagnostic severity, emotional problems, and maternal affective symptoms. At time 1 mean chronological age was 28.5 months. Children were administered the Autism Diagnostic Observation Schedule (ADOS) and Mullen Scales of Early Learning (MSEL). Parents completed the Infant Toddler Sensory Profile (ITSP), Infant-Toddler Social Emotional Assessment (ITSEA), Beck Anxiety Index (BAI), and the Center for Epidemiologic Studies Depression Inventory (CES-D) at time 1; and the Parenting Stress Index (PSI) and Family Life Impairment Scale (FLIS) at the three annual time-points. Latent Growth Curve Models indicated that higher SOR scores on the ITSP at time 1 were associated with higher initial levels of family life impairment and parenting stress and with a smaller magnitude of change over time. These associations were independent of severity of ADOS social-communication symptoms, MSEL composite score, ITSEA externalizing and anxiety symptoms, and maternal affective symptoms as measured by the BAI and CES-D. On average FLIS and PSI did not change over time, however, there was significant individual variability. Concurrently, SOR at time 1 explained 39-45% of the variance in family stress and impairment variables. An evaluation of SOR should be integrated into the assessment of toddlers with ASD considering their role in family life impairment and stress. © 2013 The Authors. Journal of Child Psychology and Psychiatry © 2013 Association for Child and Adolescent Mental Health.

  5. Coeliac disease and the liver: spectrum of liver histology, serology and treatment response at a tertiary referral centre.

    Science.gov (United States)

    Majumdar, Kaushik; Sakhuja, Puja; Puri, Amarender Singh; Gaur, Kavita; Haider, Aiman; Gondal, Ranjana

    2018-05-01

    Coeliac disease (CD) is a gluten-sensitive enteropathy diagnosed on the basis of ESPGHAN criteria and clinical response to gluten-free diet (GFD). Histological abnormalities on liver biopsy have been noted in CD but have seldom been described. To assess the histological spectrum of 'coeliac hepatitis' and possibility of reversal of such features after a GFD. Twenty-five patients with concomitant CD and hepatic derangement were analysed for clinical profile, laboratory investigations and duodenal and liver biopsy. A histological comparison of pre- and post-GFD duodenal and liver biopsies was carried out, wherever possible. Fifteen patients presenting with CD subsequently developed abnormal liver function tests; 10 patients presenting with liver disease were found to have tissue positive transglutaminase in 70% and antigliadin antibodies in 60%. Serological markers for autoimmune liver disease (AILD) were positive in eight patients. Liver histology ranged from mild reactive hepatitis, chronic hepatitis, steatosis to cirrhosis. Liver biopsies after a GFD were available in six cases, of which five showed a decrease in steatosis, portal and lobular inflammation and fibrosis score. Coeliac hepatitis could be a distinct entity and the patients may present with either CD or secondary hepatic derangement. Evaluation for the presence of CD is recommended for patients presenting with AILD, unexplained transaminasaemia or anaemia. This is one of the very few studies demonstrating the continuum of liver histological changes in 'coeliac hepatitis'. Trial of a GFD may result in clinicopathological improvement of 'coeliac hepatitis'. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  6. Analysis of the 3C 445 soft X-ray spectrum as observed by Chandra high-energy gratings

    Science.gov (United States)

    Dong, Fu-Tong; Shao, Shu-Hua; Cheng, Yan; Zeng, Jiao-Long

    2018-05-01

    We present a detailed analysis of the soft X-ray emission of 3C 445 using an archival Chandra High Energy Transmission Grating (HETG) spectrum. Highly-ionized H- and He-like Mg, Si and S lines, as well as a resolved low-ionized Si Kα line, are detected in the high resolution spectrum. The He-like triplets of Mg and Si are resolved into individual lines, and the calculated R ratios indicate a high density for the emitter. The low values of G ratios indicate the lines originate from collisionally ionized plasmas. However, the detection of a resolved narrow Ne X radiative recombination continua (RRC) feature in the spectrum seems to prefer a photoionized environment. The spectrum is subsequently modeled with a photoionization model, and the results are compared with those of a collisional model. Through a detailed analysis of the spectrum, we exclude a collisional origin for these emission lines. A one-component photoionization model provides a great fit to the emission features. The best-fit parameters are {log} ξ ={3.3}-0.3+0.4 erg cm s‑1, {n}{{H}}={5}-4.5+15× {10}10 cm‑3 and {N}{{H}}={2.5}-1.7+3.8× {10}20 cm‑2. According to the calculated high density for the emitter, the measured velocity widths of the emission lines and the inferred radial distance (6 × 1014 – 8 × 1015 cm), we suggest the emission lines originating from matter are located in the broad line region (BLR).

  7. Analysis of thick source alpha particle spectrum from radium and its daughters in bone

    International Nuclear Information System (INIS)

    Mausner, L.F.; Schlenker, R.A.

    1978-01-01

    The alpha particle energy spectrum of 226 Ra and its four alpha emitting daughters in an ashed, ground bone sample has been resolved into its components using a computerized spectrum stripping algorithm. These calculated results have been compared to direct measurements of the 226 Ra and 214 Po distributions obtained by alpha--gamma coincidence techniques. The ability of the calculation to deconvolute the total spectrum into its five alpha components implies that straightforward alpha counting may be used instead of the very low efficiency 226 Ra alpha--gamma coincidence method. From knowledge of the actual 226 Ra distribution, along with suitable detector energy and efficiency calibrations, one could determine endosteal cell dose rate empirically

  8. Analysis of the spectrum distribution of oscillation amplitudes of the concrete mix at shock vibration molding

    Directory of Open Access Journals (Sweden)

    Sharapov Rashid

    2017-01-01

    Full Text Available In the production of concrete structures widespread shaking tables of various designs. The effectiveness of vibroforming concrete items largely depends on the choice of rational modes of vibroeffect to the compacting mixture. The article discusses the propagation of a wave packet in the concrete mixture under shock and vibration molding. Studies have shown that the spectrum of a wave packet contains a large number of harmonics. The main parameter influencing the amplitude-frequency spectrum is the stiffness of elastic gaskets between mold and forming machine vibrating table. By varying the stiffness of the elastic gaskets can widely change the spectrum of the oscillations propagating in the concrete mix. Thus, it is possible to adjust the intensity of the process of vibroforming.

  9. Ambient Response Analysis Modal Analysis for Large Structures

    DEFF Research Database (Denmark)

    Brincker, Rune; Andersen, Palle

    1999-01-01

    In this paper an outline is given of the basic ideas in ambient respons analysis, i.e. when modal analyses is performed on systems based on output only. Some of the most known techniques are briefly introduced, and the basic problems discussed. The introduced techniques are the frequency domain...... based peak-picking methods, the polyreference LSCE method, the stochastic subspace method for estimation of state space systems and the prediction error method for estimation of Auto-Regressive Moving Average Vector models. The techniques are illustrated on an example of ambient response measurments...

  10. Broad-spectrum physical fitness benefits of recreational football: a systematic review and meta-analysis.

    Science.gov (United States)

    Milanović, Zoran; Pantelić, Saša; Čović, Nedim; Sporiš, Goran; Mohr, Magni; Krustrup, Peter

    2018-01-25

    participants with mild hypertension (11 and 7 mm Hg decrease, respectively) and participants with prehypertension (10 and 7 mm Hg decrease, respectively). Meta-analysis of recreational football determined the impact on resting heart rate as most likely extremely largely beneficial (ES=6.03 beats/min; 95% CI 4.43 to 7.64) when compared with non-active groups. The observed recreational football effect on fat mass was most likely largely beneficial (ES=1.72 kg; 95% CI 0.86 to 2.58) and the effect on countermovement jump (CMJ) performance was most likely very largely beneficial (ES=2.27 cm; 95% CI 1.29 to 3.25) when compared with non-active groups. Possibly beneficial decreases were found in low-density lipoprotein levels (ES=0.21 mmol/L; 95% CI 0.06 to 0.36). Possibly largely beneficial effect was observed for DBP in comparison with continuous running training. Small harmful and unclear results were noted for SBP, fat and lean body mass, body mass index, as well as muscular fitness when compared with running and Zumba training. The present meta-analysis demonstrated multiple broad-spectrum benefits of recreational football on health-related physical fitness compared with no-exercise controls, including improvements in blood pressure, resting heart rate, fat mass, low-density lipoprotein cholesterol and CMJ performance. Additionally, recreational football is efficient and effective as Zumba and continuous running exercise regimens with highlighted social, motivational and competitive components. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  11. Are autistic traits measured equivalently in individuals with and without an autism spectrum disorder? An invariance analysis of the Autism Spectrum Quotient Short Form.

    Science.gov (United States)

    Murray, Aja L; Booth, Tom; McKenzie, Karen; Kuenssberg, Renate; O'Donnell, Michael

    2014-01-01

    It is common to administer measures of autistic traits to those without autism spectrum disorders (ASDs) with, for example, the aim of understanding autistic personality characteristics in non-autistic individuals. Little research has examined the extent to which measures of autistic traits actually measure the same traits in the same way across those with and without an ASD. We addressed this question using a multi-group confirmatory factor invariance analysis of the Autism Quotient Short Form (AQ-S: Hoekstra et al. in J Autism Dev Disord 41(5):589-596, 2011) across those with (n = 148) and without (n = 168) ASD. Metric variance (equality of factor loadings), but not scalar invariance (equality of thresholds), held suggesting that the AQ-S measures the same latent traits in both groups, but with a bias in the manner in which trait levels are estimated. We, therefore, argue that the AQ-S can be used to investigate possible causes and consequences of autistic traits in both groups separately, but caution is due when combining or comparing levels of autistic traits across the two groups.

  12. β-delayed γ-proton decay in 56Zn: Analysis of the charged-particle spectrum

    International Nuclear Information System (INIS)

    Orrigo, S. E.A.; Ascher, P.; Cakirli, R. B.; Kozer, H. C.; Popescu, L.; Rogers, A. M.; Susoy, G.; Suzuki, T.

    2015-01-01

    A study of the β decay of the proton-rich T z = –2 nucleus 56 Zn has been reported in a recent publication. A rare and exotic decay mode, β-delayed γ-proton decay, has been observed there for the first time in the fp shell. Here, we expand on some of the details of the data analysis, focusing on the charged particle spectrum

  13. Inclusive Elementary Classroom Teacher Knowledge of and Attitudes toward Applied Behavior Analysis and Autism Spectrum Disorder and Their Use of Applied Behavior Analysis

    Science.gov (United States)

    McCormick, Jennifer A.

    2011-01-01

    The purpose of this study was to examine inclusive elementary teacher knowledge and attitude toward Autism Spectrum Disorder (ASD) and applied behavior analysis (ABA) and their use of ABA. Furthermore, this study examined if knowledge and attitude predicted use of ABA. A survey was developed and administered through a web-based program. Of the…

  14. Anxiety Levels in Children with Autism Spectrum Disorder : A Meta-Analysis

    NARCIS (Netherlands)

    van Steensel, F.J.A.; Heeman, E.J.

    The aim of the current study was to meta-analytically examine whether anxiety levels in children with autism spectrum disorders (ASD) are elevated. A total of 83 articles were selected from a systematic literature search and were included in the meta-analyses. Results demonstrated that children with

  15. Analysis of the spectrum of a Cartesian Perfectly Matched Layer (PML) approximation to acoustic scattering problems

    KAUST Repository

    Kim, Seungil; Pasciak, Joseph E.

    2010-01-01

    is stable for real nonzero wave numbers, we show that the essential spectrum of the higher order part only intersects the real axis at the origin. This enables us to conclude stability of the PML scattering problem from a uniqueness result given in a

  16. Standing Postural Control in Individuals with Autism Spectrum Disorder: Systematic Review and Meta-Analysis

    Science.gov (United States)

    Lim, Yi Huey; Partridge, Katie; Girdler, Sonya; Morris, Susan L.

    2017-01-01

    Impairments in postural control affect the development of motor and social skills in individuals with autism spectrum disorder (ASD). This review compared the effect of different sensory conditions on static standing postural control between ASD and neurotypical individuals. Results from 19 studies indicated a large difference in postural control…

  17. Written Expression in Individuals with Autism Spectrum Disorder: A Meta-Analysis

    Science.gov (United States)

    Finnegan, Elizabeth; Accardo, Amy L.

    2018-01-01

    Although studies exist measuring the effectiveness of writing interventions for students with autism spectrum disorder (ASD), research assessing the writing skills for this group is sparse. The present study identified differences in the written expression of individuals with ASD compared to typically developing (TD) peers, using variables…

  18. Anxiety disorders in children and adolescents with autistic spectrum disorders: a meta-analysis

    NARCIS (Netherlands)

    van Steensel, F.J.A.; Bögels, S.M.; Perrin, S.

    2011-01-01

    There is considerable evidence that children and adolescents with autistic spectrum disorders (ASD) are at increased risk of anxiety and anxiety disorders. However, it is less clear which of the specific DSM-IV anxiety disorders occur most in this population. The present study used meta-analytic

  19. Anxiety Disorders in Children and Adolescents with Autistic Spectrum Disorders: A Meta-Analysis

    Science.gov (United States)

    van Steensel, Francisca J. A.; Bogels, Susan M.; Perrin, Sean

    2011-01-01

    There is considerable evidence that children and adolescents with autistic spectrum disorders (ASD) are at increased risk of anxiety and anxiety disorders. However, it is less clear which of the specific DSM-IV anxiety disorders occur most in this population. The present study used meta-analytic techniques to help clarify this issue. A systematic…

  20. Is voice a marker for autism spectrum disorder? A systematic review and meta-analysis

    DEFF Research Database (Denmark)

    Fusaroli, Riccardo; Lambrechts, Anna; Bang, Dan

    2017-01-01

    Individuals with Autism Spectrum Disorder (ASD) tend to show distinctive, atypical acoustic patterns of speech. These behaviours affect social interactions and social development and could represent a non-invasive marker for ASD. We systematically reviewed the literature quantifying acoustic...... methods, and theory-driven research....

  1. An Analysis of Naturalistic Interventions for Increasing Spontaneous Expressive Language in Children with Autism Spectrum Disorder

    Science.gov (United States)

    Lane, Justin D.; Lieberman-Betz, Rebecca; Gast, David L.

    2016-01-01

    The purpose of this review was to identify naturalistic language interventions for increasing spontaneous expressive language (defined in this review as absence of verbal prompt or other verbalization from adults or peers) in young children with autism spectrum disorder. Also, the methodological rigor and effectiveness of each study were evaluated…

  2. Mass Spectrum Analysis of CO2 and N2 Using Ion Beam Separator System

    International Nuclear Information System (INIS)

    Tjipto-Sujitno, BA; Darsono; Agus-Santoso

    2000-01-01

    The main purpose of this research is to study investigate the massspectrum profile of CO 2 and N 2 emitted from Penning ion source using ionbeam separator. Besides that, it is also identified the compositions of CO 2 and N 2 ion gas and their abundances through their mass spectrum profile,because as we know that these ions are consist of ion of atom or molecule aswell as the their abundances. To get these profiles, the ion beam acceleratedin accelerating tube are passed through magnet separator. After passing themagnet separator, the ion current beam was detected using microampere meter.By scanning the strength of magnetic field, it will be found the currentspectrum profile as a function of magnetic field. From this current spectrum,we can make a mass spectrum profile. From experiment done, it was found thatthe mass spectrum peak of CO 2 and N 2 were C + with m/z = (12.00 ± 0.10)amu, O 2 + = (31.96 ± 0.29) amu, CO 2 + = (43.93 ± 0.31) amu, N + (13.97 ± 0.33) amu, and N 2 + = (28.05 ± 0.18) amu. (author)

  3. Functional Living Skills and Adolescents and Adults with Autism Spectrum Disorder: A Meta-Analysis

    Science.gov (United States)

    Hong, Ee Rea; Davis, John L.; Neely, Leslie; Ganz, Jennifer B.; Morin, Kristi; Ninci, Jennifer; Boles, Margot B.

    2017-01-01

    Functional living skills are skills needed for being an independent individual in society. As individuals with autism spectrum disorder (ASD) get older, the discrepancy between functional living skills of themselves and their peers increases. However, it is not known which type of intervention is more or less effective specifically for adolescent-…

  4. Melatonin in Autism Spectrum Disorders: A Systematic Review and Meta-Analysis

    Science.gov (United States)

    Rossignol, Daniel A.; Frye, Richard E.

    2011-01-01

    Aim: The aim of this study was to investigate melatonin-related findings in autism spectrum disorders (ASD), including autistic disorder, Asperger syndrome, Rett syndrome, and pervasive developmental disorders, not otherwise specified. Method: Comprehensive searches were conducted in the PubMed, Google Scholar, CINAHL, EMBASE, Scopus, and ERIC…

  5. Autism Spectrum Disorder in Down Syndrome: Cluster Analysis of Aberrant Behaviour Checklist Data Supports Diagnosis

    Science.gov (United States)

    Ji, N. Y.; Capone, G. T.; Kaufmann, W. E.

    2011-01-01

    Background: The diagnostic validity of autism spectrum disorder (ASD) based on Diagnostic and Statistical Manual of Mental Disorders (DSM) has been challenged in Down syndrome (DS), because of the high prevalence of cognitive impairments in this population. Therefore, we attempted to validate DSM-based diagnoses via an unbiased categorisation of…

  6. Psychometric Analysis of the Systematic Observation of Red Flags for Autism Spectrum Disorder in Toddlers

    Science.gov (United States)

    Dow, Deanna; Guthrie, Whitney; Stronach, Sheri T.; Wetherby, Amy M.

    2017-01-01

    The purpose of this study was to examine the utility of the Systematic Observation of Red Flags as an observational level-two screening measure to detect risk for autism spectrum disorder in toddlers when used with a video-recorded administration of the Communication and Symbolic Behavior Scales. Psychometric properties of the Systematic…

  7. GASDRA: Galaxy Spectrum Dynamic Range Analysis for Photometric Redshift Filter Partition Optimization

    Energy Technology Data Exchange (ETDEWEB)

    Vicente, J. de; Sanchez, E.; Sevilla, I.; Castilla, J.; Ponce, R.; Sanchez, F. J.

    2012-04-11

    The photometric redshift is an active area of research. It is becoming the preferred method for redshift measurement above spectroscopy one for large surveys. In these surveys, the requirement in redshift precision is relaxed in benefit of obtaining the measurements of large number of galaxies. One of the more relevant decisions to be taken in the design of a photometric redshift experiment is the number of filters since it affects deeply to the precision and survey time. Currently, there is not a clear method for evaluating the impact in both precision and exposure time of a determined filter partition set and usually it is determined by detailed simulations on the behavior of photo-z algorithms. In this note we describe GASDRA, a new method for extracting the minimal signal to noise requirement, depending on the number of filters needed for preserving the filtered spectrum shape, and hence to make feasible the spectrum identification. The application of this requirement guaranties a determined precision in the spectrum measurement. Although it cannot be translated directly to absolute photometric redshift error, it does provide a method for comparing the relative precision achieved in the spectrum representation by different sets of filters. We foresee that this relative precision is close related to photo-z error. In addition, we can evaluate the impact in the exposure time of any filter partition set with respect to other. (Author) 11 refs.

  8. Quantum analysis of the background in X-ray appearance potential spectrum

    International Nuclear Information System (INIS)

    Zhang Bowen; Zhang Nailing

    1988-01-01

    A mathematical expression of X-ray continuous spectrum is derived from the quantum theory, from which a more exact integral formula of continuous currents has been established. And expressions of first-derivative and second-derivative integrations are derived from continuous currents. A numerical integration pack of CUMSS is employed, from which numerical quadratures are calculated

  9. Antiepileptic Medications in Autism Spectrum Disorder: A Systematic Review and Meta-Analysis

    Science.gov (United States)

    Hirota, Tomoya; Veenstra-VanderWeele, Jeremy; Hollander, Eric; Kishi, Taro

    2014-01-01

    Electroencephalogram-recorded epileptiform activity is common in children with autism spectrum disorder (ASD), even without clinical seizures. A systematic literature search identified 7 randomized, placebo-controlled trials of antiepileptic drugs (AEDs) in ASD (total n = 171), including three of valproate, and one each of lamotrigine,…

  10. GASDRA: Galaxy Spectrum Dynamic Range Analysis for Photometric Redshift Filter Partition Optimization

    International Nuclear Information System (INIS)

    Vicente, J. de; Sanchez, E.; Sevilla, I.; Castilla, J.; Ponce, R.; Sanchez, F. J.

    2012-01-01

    The photometric redshift is an active area of research. It is becoming the preferred method for redshift measurement above spectroscopy one for large surveys. In these surveys, the requirement in redshift precision is relaxed in benefit of obtaining the measurements of large number of galaxies. One of the more relevant decisions to be taken in the design of a photometric redshift experiment is the number of filters since it affects deeply to the precision and survey time. Currently, there is not a clear method for evaluating the impact in both precision and exposure time of a determined filter partition set and usually it is determined by detailed simulations on the behavior of photo-z algorithms. In this note we describe GASDRA, a new method for extracting the minimal signal to noise requirement, depending on the number of filters needed for preserving the filtered spectrum shape, and hence to make feasible the spectrum identification. The application of this requirement guaranties a determined precision in the spectrum measurement. Although it cannot be translated directly to absolute photometric redshift error, it does provide a method for comparing the relative precision achieved in the spectrum representation by different sets of filters. We foresee that this relative precision is close related to photo-z error. In addition, we can evaluate the impact in the exposure time of any filter partition set with respect to other. (Author) 11 refs.

  11. Simulation and study on the γ response spectrum of BGO detector by the application of monte carlo code MOCA

    International Nuclear Information System (INIS)

    Jia Wenbao; Chen Xiaowen; Xu Aiguo; Li Anmin

    2010-01-01

    Application of Monte Carlo method to build spectra library is useful to reduce experiment workload in Prompt Gamma Neutron Activation Analysis (PGNAA). The new Monte Carlo Code MOCA was used to simulate the response spectra of BGO detector for gamma rays from 137 Cs, 60 Co and neutron induced gamma rays from S and Ti. The results were compared with general code MCNP, show that the agreement of MOCA between simulation and experiment is better than MCNP. This research indicates that building spectra library by Monte Carlo method is feasible. (authors)

  12. Linux Incident Response Volatile Data Analysis Framework

    Science.gov (United States)

    McFadden, Matthew

    2013-01-01

    Cyber incident response is an emphasized subject area in cybersecurity in information technology with increased need for the protection of data. Due to ongoing threats, cybersecurity imposes many challenges and requires new investigative response techniques. In this study a Linux Incident Response Framework is designed for collecting volatile data…

  13. Corporate social responsibility: A pharmaceutical analysis

    Directory of Open Access Journals (Sweden)

    D. J. Theron

    2005-12-01

    Full Text Available In the modern business environment organisations need to address two important aspects affecting their operations: the quality of management and the impact of their operations on the well-being of the society in which they operate. This dualism often results in economic, political and social dilemmas influencing the viability of organisations in general, and more specifically and recently, local and international pharmaceutical organisations operating in South Africa. This article considers the aspect of corporate social responsibility (CSR in general and attempts to identify the social-related issues impacting on the pharmaceutical industry by means of content analysis - a research technique for making replicable and valid inferences from data. It furthermore describes the re-action of pharmaceutical organisations when confronted with such social demands, and finally analyses the management of CSR against four criteria of CSR. The article confirms the importance of managers to manage CSR towards society in a proactive manner. It furthermore suggests that the "hard" factors of strategic management and financial performance should be balanced with "soft" social/people issues. It also recommends that the industry should consider - and if applicable - endorse the concept of Issues Management as an approach to the proactive management of CSR.

  14. A comparison of semiconductor gamma spectrometric analysis using the peak net area calculations and the whole spectrum processing

    International Nuclear Information System (INIS)

    Krnac, S.; Koskelo, M.; Venkatamaran, R.

    1998-01-01

    This study was conducted to compare the results of gamma spectrometric analysis using the Scaling Confirmatory Factor Analysis (SCFA) method to that of Genie2K, which uses a more traditional method. Gamma ray spectra had had been acquired for several gamma standard sources, all of which except Co-57 and Eu-152 being single gamma ray emitting nuclides. These standard sources spanned the energy range from 60 keV (Am-241) to 1116 keV (Zn-65). The standard sources were counted at 3 different geometries at 3 different geometries, with source-detector distances of 0, 5, and 15 cm. Using single gamma ray spectra collected at a given counting geometry, and the certificate file, an efficiency calibration was created for that geometry. Three different test spectra, one for each counting geometry, had been created by combining several of the standard source spectra. The efficiency calibrations created for the 3 geometries were loaded into the respective spectrum files. Each test spectrum was analyzed using the standard Genie2K engines; Peak locate, Peak search, Interactive peak fit, Background subs-traction, Efficiency correction, and Nuclide Identification with interference analysis. The results of the various calculation steps were reported. In all 3 test cases, the SCFA method identified all the nuclides correctly. The K-40 activities calculated by the SCFA method were reasonably close to that from Genie2K analysis. In general, the quantitative results of the SCFA method were impressive in all 3 cases. On a positive note, the SCFA method did identify low yield gamma lines in Eu-152, which were not identified by the Genie2K analysis. This substantiates claim that the SCFA is more sensitive than the traditional method of spectrum analysis. (authors)

  15. A few approaches to remove ambiguous factors in x-ray spectrum analysis

    International Nuclear Information System (INIS)

    Sera, K.; Futatsugawa, S.

    1993-01-01

    A few attempts have been done to reduce ambiguous factors in the analysis of complex x-ray spectra. Uncertainty in peak identification and separation due to overlapping of x-ray peaks can be reduced by taking into account the response function of x-ray peaks and by using peak functions including all the x-ray sub-lines in a x-ray series. Ambiguous factors due to discontinuity of backgrounds which is sometimes followed by huge peaks can be reduced by considering contributions from the pile-up, escape and tail functions. The problem of uncertainty in the background fitting in a region of low x-ray energy, where many peaks overlap each other and determination of the background function contains much difficulties and ambiguities, can be solved by using peak functions involving tails in place of Gaussians. (author)

  16. The emotion dysregulation inventory: Psychometric properties and item response theory calibration in an autism spectrum disorder sample.

    Science.gov (United States)

    Mazefsky, Carla A; Yu, Lan; White, Susan W; Siegel, Matthew; Pilkonis, Paul A

    2018-04-06

    Individuals with autism spectrum disorder (ASD) often present with prominent emotion dysregulation that requires treatment but can be difficult to measure. The Emotion Dysregulation Inventory (EDI) was created using methods developed by the Patient-Reported Outcomes Measurement Information System (PROMIS ® ) to capture observable indicators of poor emotion regulation. Caregivers of 1,755 youth with ASD completed 66 candidate EDI items, and the final 30 items were selected based on classical test theory and item response theory (IRT) analyses. The analyses identified two factors: (a) Reactivity, characterized by intense, rapidly escalating, sustained, and poorly regulated negative emotional reactions, and (b) Dysphoria, characterized by anhedonia, sadness, and nervousness. The final items did not show differential item functioning (DIF) based on gender, age, intellectual ability, or verbal ability. Because the final items were calibrated using IRT, even a small number of items offers high precision, minimizing respondent burden. IRT co-calibration of the EDI with related measures demonstrated its superiority in assessing the severity of emotion dysregulation with as few as seven items. Validity of the EDI was supported by expert review, its association with related constructs (e.g., anxiety and depression symptoms, aggression), higher scores in psychiatric inpatients with ASD compared to a community ASD sample, and demonstration of test-retest stability and sensitivity to change. In sum, the EDI provides an efficient and sensitive method to measure emotion dysregulation for clinical assessment, monitoring, and research in youth with ASD of any level of cognitive or verbal ability. Autism Res 2018. © 2018 International Society for Autism Research, Wiley Periodicals, Inc. This paper describes a new measure of poor emotional control called the Emotion Dysregulation Inventory (EDI). Caregivers of 1,755 youth with ASD completed candidate items, and advanced statistical

  17. Autism and classical eyeblink conditioning: Performance changes of the conditioned response related to autism spectrum disorder diagnosis

    Directory of Open Access Journals (Sweden)

    John P Welsh

    2016-08-01

    Full Text Available Changes in the timing performance of conditioned responses (CRs acquired during trace and delay eyeblink conditioning (EBC are presented for diagnostic subgroups of children having autism spectrum disorder (ASD aged 6-15 years. Children diagnosed with autistic disorder (AD were analyzed separately from children diagnosed with either Asperger’s syndrome or Pervasive-developmental disorder not-otherwise-specified (Asp/PDD and compared to an age- and IQ-matched group of children that were typically developing (TD. Within-subject and between-groups contrasts in CR performance on sequential exposure to trace and delay EBC were analyzed to determine whether any differences would expose underlying functional heterogeneities of the cerebral and cerebellar systems in ASD subgroups. The EBC parameters measured were percentage CRs, CR onset latency, and CR peak latency. Neither AD nor Asp/PDD groups were impaired in CR acquisition during trace or delay EBC. AD and Asp/PDD both altered CR timing, but not always in the same way. Although the AD group showed normal CR timing during trace EBC, the Asp/PDD group showed a significant 27 and 28 ms increase in CR onset and peak latency, respectively, during trace EBC. In contrast, the direction of the timing change was opposite during delay EBC, during which the Asp/PDD group showed a significant 29 ms decrease in CR onset latency and the AD group showed a larger 77 ms decrease in CR onset latency. Only the AD group showed a decrease in CR peak latency during delay EBC, demonstrating another difference between AD and Asp/PDD. The difference in CR onset latency during delay EBC for both AD and Asp/PDD was due to an abnormal prevalence of early onset CRs that were intermixed with CRs having normal timing, as observed both in CR onset histograms and mean CR waveforms. In conclusion, significant heterogeneity in EBC performance was apparent within diagnostic groups, and this may indicate that EBC performance can

  18. Meta-analysis of gray matter abnormalities in autism spectrum disorder: should Asperger disorder be subsumed under a broader umbrella of autistic spectrum disorder?

    Science.gov (United States)

    Via, Esther; Radua, Joaquim; Cardoner, Narcis; Happé, Francesca; Mataix-Cols, David

    2011-04-01

    Studies investigating abnormalities of regional gray matter volume in autism spectrum disorder (ASD) have yielded contradictory results. It is unclear whether the current subtyping of ASD into autistic disorder and Asperger disorder is neurobiologically valid. To conduct a quantitative meta-analysis of voxel-based morphometry studies exploring gray matter volume abnormalities in ASD, to examine potential neurobiological differences among ASD subtypes, and to create an online database to facilitate replication and further analyses by other researchers. We retrieved studies from PubMed, ScienceDirect, Scopus, and Web of Knowledge databases between June 3, 1999, the date of the first voxel-based morphometry study in ASD, and October 31, 2010. Studies were also retrieved from reference lists and review articles. We contacted authors soliciting additional data. Twenty-four data sets met inclusion criteria, comprising 496 participants with ASD and 471 healthy control individuals. Peak coordinates of clusters of regional gray matter differences between participants with ASD and controls, as well as demographic, clinical, and methodologic variables, were extracted from each study or obtained from the authors. No differences in overall gray matter volume were found between participants with ASD and healthy controls. Participants with ASD were found to have robust decreases of gray matter volume in the bilateral amygdala-hippocampus complex and the bilateral precuneus. A small increase of gray matter volume in the middle-inferior frontal gyrus was also found. No significant differences in overall or regional gray matter volumes were found between autistic disorder and Asperger disorder. Decreases of gray matter volume in the right precuneus were statistically higher in adults than in adolescents with ASD. These results confirm the crucial involvement of structures linked to social cognition in ASD. The absence of significant differences between ASD subtypes may have

  19. Multifrequency spectrum analysis using fully digital G Mode-Kelvin probe force microscopy

    International Nuclear Information System (INIS)

    Collins, Liam; Belianinov, Alex; Somnath, Suhas; Balke, Nina; Kalinin, Sergei V; Jesse, Stephen; Rodriguez, Brian J

    2016-01-01

    Since its inception over two decades ago, Kelvin probe force microscopy (KPFM) has become the standard technique for characterizing electrostatic, electrochemical and electronic properties at the nanoscale. In this work, we present a purely digital, software-based approach to KPFM utilizing big data acquisition and analysis methods. General mode (G-Mode) KPFM works by capturing the entire photodetector data stream, typically at the sampling rate limit, followed by subsequent de-noising, analysis and compression of the cantilever response. We demonstrate that the G-Mode approach allows simultaneous multi-harmonic detection, combined with on-the-fly transfer function correction—required for quantitative CPD mapping. The KPFM approach outlined in this work significantly simplifies the technique by avoiding cumbersome instrumentation optimization steps (i.e. lock in parameters, feedback gains etc), while also retaining the flexibility to be implemented on any atomic force microscopy platform. We demonstrate the added advantages of G-Mode KPFM by allowing simultaneous mapping of CPD and capacitance gradient (C′) channels as well as increased flexibility in data exploration across frequency, time, space, and noise domains. G-Mode KPFM is particularly suitable for characterizing voltage sensitive materials or for operation in conductive electrolytes, and will be useful for probing electrodynamics in photovoltaics, liquids and ionic conductors. (paper)

  20. Multi-dimensional spectrum analysis for 2-D vector velocity estimation

    DEFF Research Database (Denmark)

    Oddershede, Niels; Løvstakken, Lasse; Torp, Hans

    2007-01-01

    Fourier space, which is found through the 3-D Fourier transform of the data matrix, and that the plane is tilted according to the axial and lateral velocity components. Two estimators are derived for finding the plane in the 3-D Fourier space, where the integrated power spectrum is largest. The first uses...... the 3-D Fourier transform to find the power spectrum, while the second uses a minimum variance approach. Based on this plane, the axial and lateral velocity components are estimated. A number of phantom How measurements, for flow-to-beam angles of 60, 75, and 90 degrees, were performed to test...... the estimator. The data were collected using our RASMUS experimental ultrasound scanner and a 128 element commercial linear array transducer. The receive apodization function was manipulated, creating an oscillation in the lateral direction, and multiple parallel lines were beamformed simultaneously. The two...

  1. Inherent optical properties of Zamzam water in the visible spectrum: Dispersion analysis

    International Nuclear Information System (INIS)

    El-Zaiat, S.Y.

    2007-01-01

    Water samples have been taken from Zamzam well that is located in the holy city of Makkah in the Kingdom of Saudi Arabia. Refractive indices of Zamzam water samples have been measured by an Abbe refractometer at six discrete wavelengths across the visible spectrum. Some related optical parameters such as: group refractive index; permittivity; specific refraction; polarizability; reflectance and transmittance have been deduced. Dispersion of these optical parameters across the visible spectrum has been calculated. For comparison, these optical parameters have been determined for two samples of bottled drinking and distilled waters. Also the Abbe number and the single oscillator constants for the three waters have been calculated. Error analyses of the measured and calculated optical parameters have been given. It has been concluded that Zamzam water has special optical parameters that are different than those of bottled bottled drinking and distilled waters. (author)

  2. Bayesian Analysis of the Power Spectrum of the Cosmic Microwave Background

    Science.gov (United States)

    Jewell, Jeffrey B.; Eriksen, H. K.; O'Dwyer, I. J.; Wandelt, B. D.

    2005-01-01

    There is a wealth of cosmological information encoded in the spatial power spectrum of temperature anisotropies of the cosmic microwave background. The sky, when viewed in the microwave, is very uniform, with a nearly perfect blackbody spectrum at 2.7 degrees. Very small amplitude brightness fluctuations (to one part in a million!!) trace small density perturbations in the early universe (roughly 300,000 years after the Big Bang), which later grow through gravitational instability to the large-scale structure seen in redshift surveys... In this talk, I will discuss a Bayesian formulation of this problem; discuss a Gibbs sampling approach to numerically sampling from the Bayesian posterior, and the application of this approach to the first-year data from the Wilkinson Microwave Anisotropy Probe. I will also comment on recent algorithmic developments for this approach to be tractable for the even more massive data set to be returned from the Planck satellite.

  3. Experimental and theoretical analysis of the spectrum of transient electromagnetic field created by linac electron beam

    International Nuclear Information System (INIS)

    Itoh, Hiroyasu; Tomioka, Satoshi; Enoto, Takeaki

    1994-01-01

    Wave information about micro-pulses of electron beams is required in order to control an electron beam precisely, and it may be possible to obtain such information by analyzing the spectrum of the electromagnetic field created by a linac electron beam. In order to derive the spectrum, we measured the spatial distribution generated by a standing wave. Furthermore we calculated the transient electromagnetic field excited by a bunched electron beam, using the finite-difference time-domain (FD-TD) method, and compared two spectra in the frequency domain, into which the calculated value in time variation and the measured values in spatial variation are transformed by using the fast Fourier transform (FFT) respectively. (author)

  4. Brillouin Scattering Spectrum Analysis Based on Auto-Regressive Spectral Estimation

    Science.gov (United States)

    Huang, Mengyun; Li, Wei; Liu, Zhangyun; Cheng, Linghao; Guan, Bai-Ou

    2018-06-01

    Auto-regressive (AR) spectral estimation technology is proposed to analyze the Brillouin scattering spectrum in Brillouin optical time-domain refelectometry. It shows that AR based method can reliably estimate the Brillouin frequency shift with an accuracy much better than fast Fourier transform (FFT) based methods provided the data length is not too short. It enables about 3 times improvement over FFT at a moderate spatial resolution.

  5. Rotational Spectrum of 1,1-Difluoroethane: Internal Rotation Analysis and Structure

    Science.gov (United States)

    Villamanan, R. M.; Chen, W. D.; Wlodarczak, G.; Demaison, J.; Lesarri, A. G.; Lopez, J. C.; Alonso, J. L.

    1995-05-01

    The rotational spectrum of CH3CHF2 in its ground state was measured up to 653 GHz. Accurate rotational and centrifugal distortion constants were determined. The internal rotation splittings were analyzed using the internal axis method. An ab initio structure has been calculated and a near-equilibrium structure has been estimated using offsets derived empirically. This structure was compared to an experimental r0 structure. The four lowest excited states (including the methyl torsion) have also been assigned.

  6. An ocean current inversion accuracy analysis based on a Doppler spectrum model

    Institute of Scientific and Technical Information of China (English)

    BAO Qingliu; ZHANG Youguang; LIN Mingsen; GONG Peng

    2017-01-01

    Microwave remote sensing is one of the most useful methods for observing the ocean parameters.The Doppler frequency or interferometric phase of the radar echoes can be used for an ocean surface current speed retrieval,which is widely used in spaceborne and airborne radars.While the effect of the ocean currents and waves is interactional.It is impossible to retrieve the ocean surface current speed from Doppler frequency shift directly.In order to study the relationship between the ocean surface current speed and the Doppler frequency shift,a numerical ocean surface Doppler spectrum model is established and validated with a reference.The input parameters of ocean Doppler spectrum include an ocean wave elevation model,a directional distribution function,and wind speed and direction.The suitable ocean wave elevation spectrum and the directional distribution function are selected by comparing the ocean Doppler spectrum in C band with an empirical geophysical model function (CDOP).What is more,the error sensitivities of ocean surface current speed to the wind speed and direction are analyzed.All these simulations are in Ku band.The simulation results show that the ocean surface current speed error is sensitive to the wind speed and direction errors.With VV polarization,the ocean surface current speed error is about 0.15 m/s when the wind speed error is 2 m/s,and the ocean surface current speed error is smaller than 0.3 m/s when the wind direction error is within 20° in the cross wind direction.

  7. Brillouin Scattering Spectrum Analysis Based on Auto-Regressive Spectral Estimation

    Science.gov (United States)

    Huang, Mengyun; Li, Wei; Liu, Zhangyun; Cheng, Linghao; Guan, Bai-Ou

    2018-03-01

    Auto-regressive (AR) spectral estimation technology is proposed to analyze the Brillouin scattering spectrum in Brillouin optical time-domain refelectometry. It shows that AR based method can reliably estimate the Brillouin frequency shift with an accuracy much better than fast Fourier transform (FFT) based methods provided the data length is not too short. It enables about 3 times improvement over FFT at a moderate spatial resolution.

  8. Seismic response analysis of Wolsung NPP structure and equipment subjected to scenario earthquakes

    Energy Technology Data Exchange (ETDEWEB)

    Choi, In Kil; Ahn, Seong Moon; Choun, Young Sun; Seo, Jeong Moon

    2005-03-15

    The standard response spectrum proposed by US NRC has been used as a design earthquake for the design of Korean nuclear power plant structures. However, it does not reflect the characteristic of seismological and geological of Korea. In this study, the seismic response analysis of Wolsung NPP structure and equipment were performed. Three types of input motions, artificial time histories that envelop the US NRC Regulatory Guide 1.60 spectrum and the probability based scenario earthquake spectra developed for the Korean NPP site and a typical near-fault earthquake recorded at thirty sites, were used as input motions. The acceleration, displacement and shear force responses of Wolsung containment structure due to the design earthquake were larger than those due to the other input earthquakes. But, considering displacement response increases abruptly as Wolsung NPP structure does nonlinear behavior, the reassessment of the seismic safety margin based on the displacement is necessary if the structure does nonlinear behavior; although it has adequate the seismic safety margin within elastic limit. Among the main safety-related devices, electrical cabinet and pump showed the large responses on the scenario earthquake which has the high frequency characteristic. This has great effects of the seismic capacity of the main devices installed inside of the building. This means that the design earthquake is not so conservative for the safety of the safety related nuclear power plant equipments.

  9. Seismic response analysis of Wolsung NPP structure and equipment subjected to scenario earthquakes

    International Nuclear Information System (INIS)

    Choi, In Kil; Ahn, Seong Moon; Choun, Young Sun; Seo, Jeong Moon

    2005-03-01

    The standard response spectrum proposed by US NRC has been used as a design earthquake for the design of Korean nuclear power plant structures. However, it does not reflect the characteristic of seismological and geological of Korea. In this study, the seismic response analysis of Wolsung NPP structure and equipment were performed. Three types of input motions, artificial time histories that envelop the US NRC Regulatory Guide 1.60 spectrum and the probability based scenario earthquake spectra developed for the Korean NPP site and a typical near-fault earthquake recorded at thirty sites, were used as input motions. The acceleration, displacement and shear force responses of Wolsung containment structure due to the design earthquake were larger than those due to the other input earthquakes. But, considering displacement response increases abruptly as Wolsung NPP structure does nonlinear behavior, the reassessment of the seismic safety margin based on the displacement is necessary if the structure does nonlinear behavior; although it has adequate the seismic safety margin within elastic limit. Among the main safety-related devices, electrical cabinet and pump showed the large responses on the scenario earthquake which has the high frequency characteristic. This has great effects of the seismic capacity of the main devices installed inside of the building. This means that the design earthquake is not so conservative for the safety of the safety related nuclear power plant equipments

  10. Study on Spectrum Estimation in Biophoton Emission Signal Analysis of Wheat Varieties

    Directory of Open Access Journals (Sweden)

    Yitao Liang

    2014-01-01

    Full Text Available The photon emission signal in visible range (380 nm–630 nm was measured from various wheat kernels by means of a low noise photomultiplier system. To study the features of the photon emission signal, the spectrum estimation method of the photon emission signal is described for the first time. The biophoton emission signal, belonging to four varieties of wheat, is analyzed in time domain and frequency domain. It shows that the intensity of the biophoton emission signal for four varieties of wheat kernels is relatively weak and has dramatic changes over time. Mean and mean square value are obviously different in four varieties; the range was, respectively, 3.7837 and 74.8819. The difference of variance is not significant. The range is 1.1764. The results of power spectrum estimation deduced that the biophoton emission signal is a low frequency signal, and its power spectrum is mostly distributed in the frequency less than 0.1 Hz. Then three parameters, which are spectral edge frequency, spectral gravity frequency, and power spectral entropy, are adopted to explain the features of the kernels’ spontaneous biophoton emission signal. It shows that the parameters of the spontaneous biophoton emission signal for different varieties of wheat are similar.

  11. Outage Analysis of Spectrum-Sharing over M-Block Fading with Sensing Information

    KAUST Repository

    Alabbasi, Abdulrahman

    2016-07-13

    Future wireless technologies, such as, 5G, are expected to support real-time applications with high data throughput, e.g., holographic meetings. From a bandwidth perspective, cognitive radio is a promising technology to enhance the system’s throughput via sharing the licensed spectrum. From a delay perspective, it is well known that increasing the number of decoding blocks will improve the system robustness against errors, while increasing the delay. Therefore, optimally allocating the resources to determine the tradeoff of tuning the length of decoding blocks while sharing the spectrum is a critical challenge for future wireless systems. In this work, we minimize the targeted outage probability over the block-fading channels while utilizing the spectrum-sharing concept. The secondary user’s outage region and the corresponding optimal power are derived, over twoblocks and M-blocks fading channels. We propose two suboptimal power strategies and derive the associated asymptotic lower and upper bounds on the outage probability with tractable expressions. These bounds allow us to derive the exact diversity order of the secondary user’s outage probability. To further enhance the system’s performance, we also investigate the impact of including the sensing information on the outage problem. The outage problem is then solved via proposing an alternating optimization algorithm, which utilizes the verified strict quasiconvex structure of the problem. Selected numerical results are presented to characterize the system’s behavior and show the improvements of several sharing concepts.

  12. Revised and extended analysis of the fifth spectrum of bromine: Br V

    International Nuclear Information System (INIS)

    Tauheed, A; Joshi, Y N

    2009-01-01

    The spectrum of four-times ionized bromine (Br V) has been investigated in the 350-1850 A wavelength region, which was recorded on a 3-m normal incidence spectrograph at the Antigonish laboratory using a triggered spark light source and on a 6.65-m grazing incidence spectrograph at the Zeeman laboratory in Amsterdam using a sliding spark source. We have studied the 4s 2 (4p+5p+6p+4f)+4p 3 +4s4p4d+4s4p5s configurations in the odd parity system and the 4s4p 2 , 4s 2 (4d+5d+5s+6s+7s) configurations in the even parity system. Relativistic Hartree-Fock (HFR) and least squares fitted (LSF) parametric calculations were carried out to interpret the observed spectrum. Fifty-eight Br V levels have now been established, out of which 48 are new levels. Two hundred and sixteen spectral lines have been classified in this spectrum, out of which 202 are newly classified lines. A revised value of the ionization potential has been determined to be 480 670±200 cm -1 (59.60±0.02 eV).

  13. Different Responses to Trauma in Two Children with Autistic Spectrum Disorder: The Mouth as Crossroads for the Sense of Self

    Science.gov (United States)

    Rhode, Maria

    2004-01-01

    Two contrasting cases are discussed of boys with autistic spectrum disorder who had suffered cumulative trauma. Although their material was similar in many respects, the 9-year-old made excellent progress during therapy, while the 4-year-old developed much less in spite of being in intensive treatment. This contrast is discussed with regard to…

  14. Differential Amygdala Response to Lower Face in Patients with Autistic Spectrum Disorders: An fMRI Study

    Science.gov (United States)

    Ishitobi, Makoto; Kosaka, Hirotaka; Omori, Masao; Matsumura, Yukiko; Munesue, Toshio; Mizukami, Kimiko; Shimoyama, Tomohiro; Murata, Tetsuhito; Sadato, Norihiro; Okazawa, Hidehiko; Wada, Yuji

    2011-01-01

    Much functional neuroimaging evidence indicates that autistic spectrum disorders (ASD) demonstrate marked brain abnormalities in face processing. Most of these findings were obtained from studies using tasks related to whole faces. However, individuals with ASD tend to rely more on individual parts of the face for identification than on the…

  15. Violations of Personal Space in Young People with Autism Spectrum Disorders and Williams Syndrome: Insights from the Social Responsiveness Scale

    Science.gov (United States)

    Lough, Emma; Hanley, Mary; Rodgers, Jacqui; South, Mikle; Kirk, Hannah; Kennedy, Daniel P.; Riby, Deborah M.

    2015-01-01

    Interpersonal distance regulation is crucial for successful social interactions. We investigated personal space awareness in Williams syndrome (WS) and autism spectrum disorder (ASD) compared to typical development. Parents reported that individuals with WS and ASD were significantly more likely than those developing typically to invade the…

  16. Reduced Recognition of Dynamic Facial Emotional Expressions and Emotion-Specific Response Bias in Children with an Autism Spectrum Disorder

    Science.gov (United States)

    Evers, Kris; Steyaert, Jean; Noens, Ilse; Wagemans, Johan

    2015-01-01

    Emotion labelling was evaluated in two matched samples of 6-14-year old children with and without an autism spectrum disorder (ASD; N = 45 and N = 50, resp.), using six dynamic facial expressions. The Emotion Recognition Task proved to be valuable demonstrating subtle emotion recognition difficulties in ASD, as we showed a general poorer emotion…

  17. Stochastic seismic floor response analysis method for various damping systems

    International Nuclear Information System (INIS)

    Kitada, Y.; Hattori, K.; Ogata, M.; Kanda, J.

    1991-01-01

    A study using the stochastic seismic response analysis method which is applicable for the estimation of floor response spectra is carried out. It is pointed out as a shortcoming in this stochastic seismic response analysis method, that the method tends to overestimate floor response spectra for low damping systems, e.g. 1% of the critical damping ratio. An investigation on the cause of the shortcoming is carried out and a number of improvements in this method were also made to the original method by taking correlation of successive peaks in a response time history into account. The application of the improved method to a typical BWR reactor building is carried out. The resultant floor response spectra are compared with those obtained by deterministic time history analysis. Floor response spectra estimated by the improved method consistently cover the response spectra obtained by the time history analysis for various damping ratios. (orig.)

  18. APPLICATION OF THE SPECTRUM ANALYSIS WITH USING BERG METHOD TO DEVELOPED SPECIAL SOFTWARE TOOLS FOR OPTICAL VIBRATION DIAGNOSTICS SYSTEM

    Directory of Open Access Journals (Sweden)

    E. O. Zaitsev

    2016-01-01

    Full Text Available The objective of this paper is development and experimental verification special software of spectral analysis. Spectral analysis use of controlled vibrations objects. Spectral analysis of vibration based on use maximum-entropy autoregressive method of spectral analysis by the Berg algorithm. For measured signals use preliminary analysis based on regression analysis. This analysis of the signal enables to eliminate uninformative parameters such as – the noise and the trend. For preliminary analysis developed special software tools. Non-contact measurement of mechanical vibrations parameters rotating diffusely-reflecting surfaces used in circumstances where the use of contact sensors difficult or impossible for a number of reasons, including lack of access to the object, the small size of the controlled area controlled portion has a high temperature or is affected by strong electromagnetic fields. For control use offered laser measuring system. This measuring system overcomes the shortcomings interference or Doppler optical measuring systems. Such as measure the large amplitude and inharmonious vibration. On the basis of the proposed methods developed special software tools for use measuring laser system. LabVIEW using for developed special software. Experimental research of the proposed method of vibration signals processing is checked in the analysis of the diagnostic information obtained by measuring the vibration system grinding diamond wheel cold solid tungsten-containing alloy TK8. A result of work special software tools was complex spectrum obtained «purified» from non-informative parameters. Spectrum of the signal corresponding to the vibration process observed object. 

  19. Use of an improved radiation amplification factor to estimate the effect of total ozone changes on action spectrum weighted irradiances and an instrument response function

    Science.gov (United States)

    Herman, Jay R.

    2010-12-01

    Multiple scattering radiative transfer results are used to calculate action spectrum weighted irradiances and fractional irradiance changes in terms of a power law in ozone Ω, U(Ω/200)-RAF, where the new radiation amplification factor (RAF) is just a function of solar zenith angle. Including Rayleigh scattering caused small differences in the estimated 30 year changes in action spectrum-weighted irradiances compared to estimates that neglect multiple scattering. The radiative transfer results are applied to several action spectra and to an instrument response function corresponding to the Solar Light 501 meter. The effect of changing ozone on two plant damage action spectra are shown for plants with high sensitivity to UVB (280-315 nm) and those with lower sensitivity, showing that the probability for plant damage for the latter has increased since 1979, especially at middle to high latitudes in the Southern Hemisphere. Similarly, there has been an increase in rates of erythemal skin damage and pre-vitamin D3 production corresponding to measured ozone decreases. An example conversion function is derived to obtain erythemal irradiances and the UV index from measurements with the Solar Light 501 instrument response function. An analytic expressions is given to convert changes in erythemal irradiances to changes in CIE vitamin-D action spectrum weighted irradiances.

  20. Wavelet Transform Analysis of the Power Spectrum of Centre of Pressure Signals to Detect the Critical Point Interval of Postural Control

    Science.gov (United States)

    Singh, Neeraj Kumar; Snoussi, Hichem; Hewson, David; Duchêne, Jacques

    The aim of this study was to develop a method to detecting the critical point interval (CPI) when sensory feedback is used as part of a closed-loop postural control strategy. Postural balance was evaluated using centre of pressure (COP) displacements from a force plate for 17 control and 10 elderly subjects under eyes open, eyes closed, and vibration conditions. A modified local-maximum-modulus wavelet transform analysis using the power spectrum of COP signals was used to calculate CPI. Lower CPI values indicate increased closed-loop postural control with a quicker response to sensory input. Such a strategy requires greater energy expenditure due to the repeated muscular interventions to remain stable. The CPI for elderly occurred significantly quicker than for controls, indicating tighter control of posture. Similar results were observed for eyes closed and vibration conditions. The CPI parameter can be used to detect differences in postural control due to ageing.