WorldWideScience

Sample records for response act ahera

  1. Comprehensive Environmental Response, Compensation and Liability Act

    National Oceanic and Atmospheric Administration, Department of Commerce — This data represents geographic terms used within the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). CERCLA, commonly known as...

  2. Freedom of Information Act-Employee responsibilities

    Newman, David J.

    2012-01-01

    The Freedom of Information Act( FOIA), 5 U.S.C. § 552, as amended, generally provides that any person has a right to request access to Federal agency records. The USGS proactively promotes information disclosure as inherent to its mission of providing objective science to inform decisionmakers and the general public. USGS scientists disseminate up-to-date and historical scientific data that are critical to addressing national and global priorities.

  3. 20 CFR 401.30 - Privacy Act and other responsibilities.

    2010-04-01

    ... information privacy issues, including those relating to the collection, use, sharing, and disclosure of... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Privacy Act and other responsibilities. 401.30 Section 401.30 Employees' Benefits SOCIAL SECURITY ADMINISTRATION PRIVACY AND DISCLOSURE OF...

  4. Controversies Concerning the Canadian Not Criminally Responsible Reform Act.

    Lacroix, Robert; O'Shaughnessy, Roy; McNiel, Dale E; Binder, Renée L

    2017-03-01

    In Canada, individuals found not criminally responsible on account of mental disorder are subject to the disposition recommendations of the Provincial or Territorial Review Board of the jurisdiction where the offense was committed. Bill C-14, known as "The Not Criminally Responsible Reform Act" made changes to the postverdict disposition process of these individuals. This legislation was consistent with a broader "tough-on-crime" agenda of the previous federal government. The legislative changes codify that Review Boards take public safety as the "paramount consideration" in making their recommendations. The legislation also creates a new "high-risk" category for certain offenders and imposes limitations on their liberty. Further, Bill C-14 seeks to enhance victim involvement in the disposition process. The passage of this legislation has generated significant controversy in the medical and legal fields. Critics have stated that there is an absence of empirical evidence on which to base the amendments, that the legislation was an overreaction to high-profile cases, and that Bill C-14 is in questionable compliance with the Canadian Charter of Rights and Freedoms. In this review, we explore the potential catalysts involved in the creation of Bill C-14, the controversy surrounding the legislation, and the potential future impact on practicing forensic psychiatrists and on the forensic mental health system in Canada. © 2017 American Academy of Psychiatry and the Law.

  5. Tobacco industry responsibility for butts: a Model Tobacco Waste Act.

    Curtis, Clifton; Novotny, Thomas E; Lee, Kelley; Freiberg, Mike; McLaughlin, Ian

    2017-01-01

    Cigarette butts and other postconsumer products from tobacco use are the most common waste elements picked up worldwide each year during environmental cleanups. Under the environmental principle of Extended Producer Responsibility, tobacco product manufacturers may be held responsible for collection, transport, processing and safe disposal of tobacco product waste (TPW). Legislation has been applied to other toxic and hazardous postconsumer waste products such as paints, pesticide containers and unused pharmaceuticals, to reduce, prevent and mitigate their environmental impacts. Additional product stewardship (PS) requirements may be necessary for other stakeholders and beneficiaries of tobacco product sales and use, especially suppliers, retailers and consumers, in order to ensure effective TPW reduction. This report describes how a Model Tobacco Waste Act may be adopted by national and subnational jurisdictions to address the environmental impacts of TPW. Such a law will also reduce tobacco use and its health consequences by raising attention to the environmental hazards of TPW, increasing the price of tobacco products, and reducing the number of tobacco product retailers. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  6. The migration response to the Legal Arizona Workers Act

    Ellis, Mark; Wright, Richard; Townley, Matthew; Copeland, Kristy

    2014-01-01

    The 2008 Legal Arizona Workers Act (LAWA) requires all public and private employers to authenticate the legal status of their workers using the federal employment verification system known as E-Verify. With LAWA, Arizona became the first state to have a universal mandate for employment verification. While LAWA targets unauthorized workers, most of whom are Latino immigrants, other groups could experience LAWA’s effects, such as those who share households with undocumented workers. In addition, employers may seek to minimize their risk of LAWA penalties by not hiring those who appear to them as more likely to be unauthorized, such as naturalized Latino immigrants and US-born Latinos. Existing research has found a reduction in foreign-born Latino employment and population in response to LAWA. This paper asks a different question: have groups that are most likely to be affected by the law migrated to other states? We find a significant and sustained increase in the internal outmigration rate from Arizona of foreign-born, noncitizen Latinos - the group most likely to include the unauthorized - after the passage of LAWA. There was no significant LAWA internal migration response by foreign-born Latino citizens. US-born Latinos showed some signs of a LAWA-induced internal migration response after the law went into effect, but it is not sustained. The results indicate that local and state immigration policy can alter the settlement geography of the foreign born. This leads us to speculate about how immigrant settlement may adjust in the coming years to the intersecting geographies of post-recession economic opportunity and tiered immigration policies. PMID:25018590

  7. Flexible ACT & Resource-group ACT: Different Working Procedures Which Can Supplement and Strengthen Each Other. A Response.

    van Veldhuizen, Remmers; Delespaul, Philippe; Kroon, Hans; Mulder, Niels

    2015-01-01

    This article is a response to Nordén and Norlander's 'Absence of Positive Results for Flexible Assertive Community Treatment. What is the next approach?'[1], in which they assert that 'at present [there is] no evidence for Flexible ACT and… that RACT might be able to provide new impulses and new vitality to the treatment mode of ACT'. We question their analyses and conclusions. We clarify Flexible ACT, referring to the Flexible Assertive Community Treatment Manual (van Veldhuizen, 2013) [2] to rectify misconceptions. We discuss Nordén and Norlander's interpretation of research on Flexible ACT. The fact that too little research has been done and that there are insufficient positive results cannot serve as a reason to propagate RACT. However, the Resource Group method does provide inspiration for working with clients to involve their networks more effectively in Flexible ACT.

  8. Delegation of Authority Under the Community Environmental Response Facilitation Act (CERFA) - Decision Memorandum

    This memorandum concerns how the Office of Enforcement (OE) proposed that two new authorities under the Community Environmental Response Facilitation Act (CERFA) be delegated to the Regional Administrators.

  9. Occupational Safety and Health Act: A Responsibility for Science Teachers

    Science Teacher, 1974

    1974-01-01

    Presents implications of the Occupational Safety and Health Act for science teachers both as workers and as they encourage, in students, the development of positive safety attitudes for future occupations. (PEB)

  10. Flexible ACT & Resource-group ACT: Different Working Procedures Which Can Supplement and Strengthen Each Other. A Response#

    van Veldhuizen, Remmers; Delespaul, Philippe; Kroon, Hans; Mulder, Niels

    2015-01-01

    This article is a response to Nordén and Norlander’s ‘Absence of Positive Results for Flexible Assertive Community Treatment. What is the next approach?’[1], in which they assert that ‘at present [there is] no evidence for Flexible ACT and… that RACT might be able to provide new impulses and new vitality to the treatment mode of ACT’. We question their analyses and conclusions. We clarify Flexible ACT, referring to the Flexible Assertive Community Treatment Manual (van Veldhuizen, 2013) [2] to rectify misconceptions. We discuss Nordén and Norlander’s interpretation of research on Flexible ACT. The fact that too little research has been done and that there are insufficient positive results cannot serve as a reason to propagate RACT. However, the Resource Group method does provide inspiration for working with clients to involve their networks more effectively in Flexible ACT. PMID:25767558

  11. Flexible ACT & Resource-group ACT : Different Working Procedures Which Can Supplement and Strengthen Each Other. A Response

    van Veldhuizen, Remmers; Delespaul, Philippe; Kroon, Hans; Mulder, Niels

    2015-01-01

    This article is a response to Nordén and Norlander's 'Absence of Positive Results for Flexible Assertive Community Treatment. What is the next approach?'[1], in which they assert that 'at present [there is] no evidence for Flexible ACT and… that RACT might be able to provide new impulses and new

  12. Organization of cis-acting regulatory elements in osmotic- and cold-stress-responsive promoters.

    Yamaguchi-Shinozaki, Kazuko; Shinozaki, Kazuo

    2005-02-01

    cis-Acting regulatory elements are important molecular switches involved in the transcriptional regulation of a dynamic network of gene activities controlling various biological processes, including abiotic stress responses, hormone responses and developmental processes. In particular, understanding regulatory gene networks in stress response cascades depends on successful functional analyses of cis-acting elements. The ever-improving accuracy of transcriptome expression profiling has led to the identification of various combinations of cis-acting elements in the promoter regions of stress-inducible genes involved in stress and hormone responses. Here we discuss major cis-acting elements, such as the ABA-responsive element (ABRE) and the dehydration-responsive element/C-repeat (DRE/CRT), that are a vital part of ABA-dependent and ABA-independent gene expression in osmotic and cold stress responses.

  13. 76 FR 23810 - Public Safety and Homeland Security Bureau; Federal Advisory Committee Act; Emergency Response...

    2011-04-28

    ... FEDERAL COMMUNICATIONS COMMISSION Public Safety and Homeland Security Bureau; Federal Advisory Committee Act; Emergency Response Interoperability Center Public Safety Advisory Committee Meeting AGENCY... Fullano, Associate Chief, Public Safety and Homeland Security Bureau, Federal Communications Commission...

  14. Comprehensive Environmental Response, Compensation, and Liability Act, as amended by the Superfund Amendments and Reauthorization Act Section 120(e)(5)

    1992-05-01

    The US Department of Energy (DOE) is committed to conducting its operations. In a safe and environmentally sound manner. High priorities for the Department are identifying and correcting environmental problems at DOE facilities that resulted from past operations, and preventing environmental problems from occurring during present and future operations. In this regard, the Department is committed to the 30-year goal of cleanup of all facilities by the year 2019. DOE has issued an Order and guidance establishing policy and procedures for activities conducted under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended by the Superfund Amendments and Reauthorization Act (SARA), and has developed a Five-Year Plan, updated annually, that integrates planing for corrective activities, environmental restoration, and waste management operations at its facilities. During Calendar Year 1991 and early 1992, DOE made significant progress in reaching agreements with regulatory entities, undertaking cleanup actions, and initiating preventive measures designed to eliminate future environmental problems. These accomplishments are described

  15. Malicious acts involving radioactive sources: prevention and preparedness for response

    Pradeepkumar, K.S.

    2008-01-01

    Full text: The increasing concern over the malevolent use of radioactive sources and radiological terrorism demands strengthening the preparedness for response to radiological emergencies. In spite of various security measures adopted internationally, availability of orphan sources cannot be completely ruled out. The trends in terrorism also indicates the possibility of various means which may be adopted by terrorists especially if they are aware of the challenges of radioactive contamination in public domain and the capability of 'denial of area' and the fear factor which can be injected during such radiological emergencies. It is to be well understood that whatever measures are taken by some countries in preventing the sources from getting stolen or smuggled in/out of their country are not adequate to eliminate radiological terrorism in a global level unless all nations collectively address and ensure the security of radioactive sources, hence preventing the generation of any orphan sources. While preparedness for response to various radiological emergency scenario have many common factors, the challenges involved in responding to radiological terrorism involves understanding the fear factor due to the presence of radioactive contamination after the blast and thermal effects on the victims and issues like handling of contaminated and seriously injured persons, restriction on the movement of responders and forensic teams in a contaminated field etc. Hence an understanding and anticipation of all possible means of radiological terrorism is very essential to prevent and to reduce the consequences. There are many deterrents, which are to be developed and maintained by all nations collectively which should include intelligence, wide usage of radiation monitors by customs, police and other security agencies, installation of state of the art high sensitive radiation monitors and systems etc to prevent and deter stealing and illicit trafficking of radioactive sources

  16. Oscillatory Brain Responses Reflect Anticipation during Comprehension of Speech Acts in Spoken Dialog

    Rosa S. Gisladottir

    2018-02-01

    Full Text Available Everyday conversation requires listeners to quickly recognize verbal actions, so-called speech acts, from the underspecified linguistic code and prepare a relevant response within the tight time constraints of turn-taking. The goal of this study was to determine the time-course of speech act recognition by investigating oscillatory EEG activity during comprehension of spoken dialog. Participants listened to short, spoken dialogs with target utterances that delivered three distinct speech acts (Answers, Declinations, Pre-offers. The targets were identical across conditions at lexico-syntactic and phonetic/prosodic levels but differed in the pragmatic interpretation of the speech act performed. Speech act comprehension was associated with reduced power in the alpha/beta bands just prior to Declination speech acts, relative to Answers and Pre-offers. In addition, we observed reduced power in the theta band during the beginning of Declinations, relative to Answers. Based on the role of alpha and beta desynchronization in anticipatory processes, the results are taken to indicate that anticipation plays a role in speech act recognition. Anticipation of speech acts could be critical for efficient turn-taking, allowing interactants to quickly recognize speech acts and respond within the tight time frame characteristic of conversation. The results show that anticipatory processes can be triggered by the characteristics of the interaction, including the speech act type.

  17. Grape marc extract acts as elicitor of plant defence responses.

    Goupil, Pascale; Benouaret, Razik; Charrier, Olivia; Ter Halle, Alexandra; Richard, Claire; Eyheraguibel, Boris; Thiery, Denis; Ledoigt, Gérard

    2012-07-01

    Plant protection based on novel alternative strategies is a major concern in agriculture to sustain pest management. The marc extract of red grape cultivars reveals plant defence inducer properties. Treatment with grape marc extract efficiently induced hypersensitive reaction-like lesions with cell death evidenced by Evans Blue staining of tobacco leaves. Examination of the infiltration zone and the surrounding areas under UV light revealed the accumulation of autofluorescent compounds. Both leaf infiltration and a foliar spray of the red grape extract on tobacco leaves induced defence gene expression. The PR1 and PR2 target genes were upregulated locally and systemically in tobacco plants following grape marc extract treatment. The grape extract elicited an array of plant defence responses making this natural compound a potential phytosanitary product with a challenging issue and a rather attractive option for sustainable agriculture and environmentally friendly practices.

  18. 25 CFR 224.40 - How does the Act or a TERA affect the Secretary's trust responsibility?

    2010-04-01

    ... or other Federal law. (c) The Act and this part preserve the Secretary's trust responsibility to... 25 Indians 1 2010-04-01 2010-04-01 false How does the Act or a TERA affect the Secretary's trust... DETERMINATION ACT General Provisions § 224.40 How does the Act or a TERA affect the Secretary's trust...

  19. The Illegal Immigration Reform and Immigrant Responsibility Act of 1996: an overview.

    Fragomen, A T

    1997-01-01

    "On September 30, 1996, President Clinton signed the Illegal Immigration Reform and Immigrant Responsibility Act of 1996 (1996 Act), Pub. L. No. 104-208, 110 Stat. 3009. After an intense lobbying effort by the business community, most provisions relating to legal immigration were omitted from the final bill. Instead, the 1996 Act focuses on illegal immigration reform and includes some of the toughest measures ever taken against illegal immigration." Aspects considered include border enforcement, penalities against alien smuggling and document fraud, deportation and exclusion proceedings, employer sanctions, welfare provisions, and changes to existing refugee and asylum procedures. excerpt

  20. Initial Northwest Power Act Power Sales Contracts : Final Environmental Impact Statement. Volume 4, Comments and Responses.

    United States. Bonneville Power Administration.

    1992-01-01

    This volume of the Initial Northwest Power Act Power Sales Contracts Final Environmental Impact Statement (Final EIS) contains public comments addressing the Initial Northwest Power Act Power Sales Contracts Draft EIS, August 1990 and Bonneville Power Administration`s (BPA) responses. The Introduction provides information about the process BPA follows in addressing these comments. Part I contains a listing of the Alternative Actions evaluated in the Final EIS; Part II is organized by Alternatives and includes summaries of the comments and BPA responses; Part III provides copies of the original comments letters, and, for ease of identification, are coded in the margins according to the alternative(s) addressed.

  1. NRC Response to an Act or Threat of Terrorism at an NRC-Licensed Facility

    Frank Congel

    2000-01-01

    The mandated response to a threat or act of terrorism at a U.S. Nuclear Regulatory Commission (NRC)-licensed facility was examined through a tabletop exercise in May 2000 and a limited field exercise in August 2000. This paper describes some of the new issues addressed and lessons learned from those exercises

  2. 5 CFR 2606.106 - OGE employee Privacy Act rules of conduct and responsibilities.

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false OGE employee Privacy Act rules of conduct and responsibilities. 2606.106 Section 2606.106 Administrative Personnel OFFICE OF GOVERNMENT ETHICS... requirement to inform each individual asked to supply information to be maintained in a system of records the...

  3. Responsiveness of migraine-ACT and MIDAS questionnaires for assessing migraine therapy.

    García, María Luisa; Baos, Vicente; Láinez, Miguel; Pascual, Julio; López-Gil, Arturo

    2008-10-01

    Migraine is frequently undertreated. The 4-item Migraine Assessment of Current Therapy (Migraine-ACT) questionnaire is a simple and reliable tool to identify patients requiring a change in current acute migraine treatment. To investigate the responsiveness of the Migraine-ACT tool, and compare it with that of the Migraine Disability Assessment (MIDAS) questionnaire, for patients with migraine at 1100 primary care sites in Spain. Patients eligible for this open-label, 2-visit prospective study reported migraine for >1 year and >or=1 migraine attack per month and were new to the clinic or on follow-up care for MIDAS questionnaires were administered, and patient satisfaction with treatment was recorded, at baseline and at 3 months. A total of 3272 patients, 78% female, were enrolled, and 2877 (88%) returned for the 3-month visit. Investigators changed baseline migraine treatment for 72% of returning patients; 85% and 80% of these patients had improved Migraine-ACT and MIDAS scores at 3 months, respectively. Patients who reported being completely or very satisfied with migraine treatment numbered 492 (15%) at baseline and 1406 (49%) at 3 months. Migraine-ACT and MIDAS score agreement for improvement at 3 months was poor (kappa = 0.339). Both the mean MIDAS score and the distribution of Migraine-ACT scores improved over the course of 3 months; however, Migraine-ACT scores were significantly (P MIDAS scores. The area under the curve in the receiver-operating characteristic analysis was significantly (P MIDAS (0.70) questionnaire. These results suggest that the Migraine-ACT questionnaire can be used more reliably than the MIDAS questionnaire for detecting improvements in treatment of new and follow-up patients with migraine.

  4. Moral identity and the experience of moral elevation in response to acts of uncommon goodness.

    Aquino, Karl; McFerran, Brent; Laven, Marjorie

    2011-04-01

    Four studies using survey and experimental designs examined whether people whose moral identity is highly self-defining are more susceptible to experiencing a state of moral elevation after being exposed to acts of uncommon moral goodness. Moral elevation consists of a suite of responses that motivate prosocial action tendencies. Study 1 showed that people higher (vs. lower) in moral identity centrality reported experiencing more intense elevating emotions, had more positive views of humanity, and were more desirous of becoming a better person after reading about an act of uncommon goodness than about a merely positive situation or an act of common benevolence. Study 2 showed that those high in moral identity centrality were more likely to recall acts of moral goodness and experience moral elevation in response to such events more strongly. These experiences were positively related to self-reported prosocial behavior. Study 3 showed a direct effect on behavior using manipulated, rather than measured, moral identity centrality. Study 4 replicated the effect of moral identity on the states of elevation as well as on self-reported physical sensations and showed that the elevation mediates the relationship between moral identity, witnessing uncommon goodness, and prosocial behavior.

  5. Integrating NEPA (National Environmental Policy Act) and CERCLA (Comprehensive Environmental Response, Compensation, and Liability Act) requirements during remedial responses at DOE facilities

    Levine, M.B.; Smith, E.D.; Sharples, F.E.; Eddlemon, G.K.

    1990-07-01

    US Department of Energy (DOE) Order 5400.4, issued October 6, 1989, calls for integrating the requirements of the National Environmental Policy Act (NEPA) with those of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) for DOE remedial actions under CERCLA. CERCLA requires that decisions on site remediation be made through a formal process called a Remedial Investigation/Feasibility Study (RI/FS). According to the DOE order, integration is to be accomplished by conducting the NEPA and CERCLA environmental planning and review procedures concurrently. The primary instrument for integrating the processes is to be the RI/FS process, which will be supplemented as needed to meet the procedural and documentational requirements of NEPA. The final product of the integrated process will be a single, integrated set of documents; namely, an RI report and an FS-EIS that satisfy the requirements of both NEPA and CERCLA. The contents of the report include (1) an overview and comparison of the requirements of the two processes; (2) descriptions of the major tasks included in the integrated RI/FS-EIS process; (3) recommended contents for integrated RI/FS-EIS documents; and (4)a discussion of some potential problems in integrating NEPA and CERCLA that fall outisde the scope of the RI/FS-EIS process, with suggestions for resolving some of these problems. 15 refs.

  6. Integrating NEPA [National Environmental Policy Act] and CERCLA [Comprehensive Environmental Response, Compensation, and Liability Act] requirements during remedial responses at DOE facilities

    Levine, M.B.; Smith, E.D.; Sharples, F.E.; Eddlemon, G.K.

    1990-07-01

    US Department of Energy (DOE) Order 5400.4, issued October 6, 1989, calls for integrating the requirements of the National Environmental Policy Act (NEPA) with those of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) for DOE remedial actions under CERCLA. CERCLA requires that decisions on site remediation be made through a formal process called a Remedial Investigation/Feasibility Study (RI/FS). According to the DOE order, integration is to be accomplished by conducting the NEPA and CERCLA environmental planning and review procedures concurrently. The primary instrument for integrating the processes is to be the RI/FS process, which will be supplemented as needed to meet the procedural and documentational requirements of NEPA. The final product of the integrated process will be a single, integrated set of documents; namely, an RI report and an FS-EIS that satisfy the requirements of both NEPA and CERCLA. The contents of the report include (1) an overview and comparison of the requirements of the two processes; (2) descriptions of the major tasks included in the integrated RI/FS-EIS process; (3) recommended contents for integrated RI/FS-EIS documents; and (4)a discussion of some potential problems in integrating NEPA and CERCLA that fall outisde the scope of the RI/FS-EIS process, with suggestions for resolving some of these problems. 15 refs

  7. Reward acts as a signal to control delay-period activity in delayed-response tasks.

    Ichihara-Takeda, Satoe; Takeda, Kazuyoshi; Funahashi, Shintaro

    2010-03-31

    Prefrontal delay-period activity represents a neural mechanism for the active maintenance of information and needs to be controlled by some signal to appropriately operate working memory. To examine whether reward-delivery acts as this signal, the effects of delay-period activity in response to unexpected reward-delivery were examined by analyzing single-neuron activity recorded in the primate dorsolateral prefrontal cortex. Among neurons that showed delay-period activity, 34% showed inhibition of this activity in response to unexpected reward-delivery. The delay-period activity of these neurons was affected by the expectation of reward-delivery. The strength of the reward signal in controlling the delay-period activity is related to the strength of the effect of reward information on the delay-period activity. These results indicate that reward-delivery acts as a signal to control delay-period activity.

  8. Oil spill response planning under the Oil Pollution Act of 1990

    Lees, J.E.

    1992-01-01

    The oil spill in Alaska's Prince William Sound on March 24, 1989 illustrated the need for more resources, better planning, and better command and control to efficiently and effectively respond to, contain and cleanup catastrophic oil spills. In response to public concern and industry initiatives to resolve existing oil spill response problems. Congress enacted the comprehensive Oil Pollution Act of 1990 (OPA-90) on August 18, 1990. OPA-90 mandates comprehensive changes in vessel and facility response planning, envisioning a comprehensive and integrated oil spill response planning scheme, with revisions to reflect OPA-90's new requirements. Area Committees comprised of federal, state and local officials and others will prepare Area Contingency Plans for Coast Guard approval, which set forth the framework for responding to open-quotes worst case dischargesclose quotes. Owners and operators of tank vessels and onshore and offshore facilities must submit individual response plans for federal approval by February 18, 1993, identifying and ensuring availability of private personnel and equipment necessary to remove to the maximum extent practicable a open-quotes worst case discharge.close quotes The Coast Guard is considering rules to implement these requirements. Major challenges exist to meet the statutory requirements, including response times, skimming efficiencies, adverse weather and others that affect emergency response capability. This paper focuses on: (1) oil spill response problems identified and lessons learned from the Prince William Sound spill; (2) OPA-90's complex and technical oil spill response planning requirements and their effect on response planning for marine operations; (3) the federal regulatory program to implement OPA-90, defining spill response capability for a open-quotes worst case discharge,close quotes considering existing response resources and the new capabilities by the industry-supported Marine Spill Response Corporation

  9. Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria

    Abdulla, S.; Adam, I.; Adjei, G. O.

    2015-01-01

    values for clearance in patients from Sub-Saharan African countries with uncomplicated malaria treated with artemisinin-based combination therapies (ACTs). Methods: A literature review in PubMed was conducted in March 2013 to identify all prospective clinical trials (uncontrolled trials, controlled...... trials and randomized controlled trials), including ACTs conducted in Sub-Saharan Africa, between 1960 and 2012. Individual patient data from these studies were shared with the WorldWide Antimalarial Resistance Network (WWARN) and pooled using an a priori statistical analytical plan. Factors affecting...... early parasitological response were investigated using logistic regression with study sites fitted as a random effect. The risk of bias in included studies was evaluated based on study design, methodology and missing data. Results: In total, 29,493 patients from 84 clinical trials were included...

  10. California's response to the Low-Level Radioactive Waste Policy Act of 1980: policy and progress

    Pasternak, A.D.

    1985-01-01

    The public and private corporations and institutions in California that use radioactive materials and generate low-level radioactive waste have played a major role in shaping and guiding California's response to the federal Low-Level Radioactive Waste Policy Act of 1980. Working together as the California Radioactive Materials Management Forum (CAL RAD FORUM), these organizations carry out legislative and public education programs with the objective of establishing, in California, a low-level radioactive waste disposal facility and maintaining access to existing disposal facilities in other states until the California facility is licensed and operating

  11. Environmental Guidance Program Reference Book: Comprehensive Environmentally Response, Compensation, and Liability Act

    1991-12-31

    This Reference Book contains a current copy of the Comprehensive Environmental Response Compensation, and Liability Act and those regulations that implement the statute and appear to be most relevant to Department of Energy (DOE) activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (FTS 896-2609 or Commercial 202/586-2609).

  12. The German act on the reorganisation of responsibility in nuclear waste management

    Raetzke, Christian

    2017-01-01

    The author discussed the Draft on the Act in the Reorganisation of Responsibility in Nuclear Waste Management in atw 12 (2016). Now, amendments are discussed, which resulted from the legislative procedure until today's draft. Significant additions affect the authorisation for the conclusion of a public-law contract between the Federal Government and the nuclear power plant operators, the deadline for the payment of the basic amount, and the option for the operation of the interim storage facilities for a transitional period by the operators on behalf of the federal company. Since the adoption of the draft act, it has become clear that the nuclear power plant operators will pay the risk premium. This will fulfil the full logic of the new system. It has also become known, that the public law contract is now ready for signing. According to the author, the act will bring a final arrangement for financing nuclear waste disposal. However, adjustment can not be avoided in practice. The concrete implementation will be a exciting topic in many ways.

  13. 45 CFR 2508.8 - Who is responsible for establishing the Corporation's rules of conduct for Privacy Act compliance?

    2010-10-01

    ... Corporation's rules of conduct for Privacy Act compliance? 2508.8 Section 2508.8 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE IMPLEMENTATION OF THE PRIVACY ACT OF 1974 § 2508.8 Who is responsible for establishing the Corporation's rules of conduct for...

  14. EVALUATION OF THE IMPLEMENTATION OF OPERATIONS AND MAINTENANCE PROGRAMS IN NEW JERSEY SCHOOLS

    The Asbestos Hazard Emergency Response Act (AHERA) required all schools to develop and implement an asbestos management plan (AMP). The key component of the AMP is the operations and maintenance (O&M) program. A study was conducted to evaluate the implementation of O&M programs a...

  15. Aggregate modeling of fast-acting demand response and control under real-time pricing

    Chassin, David P.; Rondeau, Daniel

    2016-01-01

    Highlights: • Demand elasticity for fast-acting demand response load under real-time pricing. • Validated first-principles logistic demand curve matches random utility model. • Logistic demand curve suitable for diversified aggregate loads market-based transactive control systems. - Abstract: This paper develops and assesses the performance of a short-term demand response (DR) model for utility load control with applications to resource planning and control design. Long term response models tend to underestimate short-term demand response when induced by prices. This has two important consequences. First, planning studies tend to undervalue DR and often overlook its benefits in utility demand management program development. Second, when DR is not overlooked, the open-loop DR control gain estimate may be too low. This can result in overuse of load resources, control instability and excessive price volatility. Our objective is therefore to develop a more accurate and better performing short-term demand response model. We construct the model from first principles about the nature of thermostatic load control and show that the resulting formulation corresponds exactly to the Random Utility Model employed in economics to study consumer choice. The model is tested against empirical data collected from field demonstration projects and is shown to perform better than alternative models commonly used to forecast demand in normal operating conditions. The results suggest that (1) existing utility tariffs appear to be inadequate to incentivize demand response, particularly in the presence of high renewables, and (2) existing load control systems run the risk of becoming unstable if utilities close the loop on real-time prices.

  16. An Ethics of Permission: A Response to the California End of Life Option Act.

    Nelson, Craig

    2016-01-01

    An ethics of permission can be helpful in framing a response to the ethical differences surrounding the California End of Life Option Act. Law does not define morality, and reaching a moral understanding demands thorough reflection. An ethics of permission examines the ethical demands of a permissive law for both clinician and patient. Serving the good of the patient, respecting professional conscience, and following the law are three ethical elements. Although developing an ethics of permission includes these three elements, these elements do not exhaust all the moral implications involved. An ethics of permission also includes the importance of exercising professional tolerance in the honoring of clinicians who choose to participate or refuse to participate. In addition, an ethics of permission also provides insight in implementing just and fair behavior among medical professionals.

  17. Report: Response to Congressional Request on Signage Requirements for Projects Funded by the Recovery Act

    Report #10-X-0175, August 2, 2010. EPA developed two forms of guidance that discuss the need for recipients to display a Recovery Act logo to communicate to the public that the project is a Recovery Act investment.

  18. β-Catenin acts in a position-independent regeneration response in the simple eumetazoan Hydra.

    Gufler, S; Artes, B; Bielen, H; Krainer, I; Eder, M-K; Falschlunger, J; Bollmann, A; Ostermann, T; Valovka, T; Hartl, M; Bister, K; Technau, U; Hobmayer, B

    2018-01-15

    Wnt/β-Catenin signaling plays crucial roles in regenerative processes in eumetazoans. It also acts in regeneration and axial patterning in the simple freshwater polyp Hydra, whose morphallactic regenerative capacity is unparalleled in the animal kingdom. Previous studies have identified β-catenin as an early response gene activated within the first 30min in Hydra head regeneration. Here, we have studied the role of β-Catenin in more detail. First, we show that nuclear β-Catenin signaling is required for head and foot regeneration. Loss of nuclear β-Catenin function blocks head and foot regeneration. Transgenic Hydra tissue, in which β-Catenin is over-expressed, regenerates more heads and feet. In addition, we have identified a set of putative β-Catenin target genes by transcriptional profiling, and these genes exhibit distinct expression patterns in the hypostome, in the tentacles, or in an apical gradient in the body column. All of them are transcriptionally up-regulated in the tips of early head and foot regenerates. In foot regenerates, this is a transient response, and expression starts to disappear after 12-36h. ChIP experiments using an anti-HydraTcf antibody show Tcf binding at promoters of these targets. We propose that gene regulatory β-Catenin activity in the pre-patterning phase is generally required as an early regeneration response. When regenerates are blocked with iCRT14, initial local transcriptional activation of β-catenin and the target genes occurs, and all these genes remain upregulated at the site of both head and foot regeneration for the following 2-3 days. This indicates that the initial regulatory network is followed by position-specific programs that inactivate fractions of this network in order to proceed to differentiation of head or foot structures. brachyury1 (hybra1) has previously been described as early response gene in head and foot regeneration. The HyBra1 protein, however, appears in head regenerating tips not earlier

  19. Fatty liver in hepatitis C patients post-sustained virological response with direct-acting antivirals

    Noureddin, Mazen; Wong, Micaela M; Todo, Tsuyoshi; Lu, Shelly C; Sanyal, Arun J; Mena, Edward A

    2018-01-01

    AIM To determine steatosis and fibrosis prevalence in hepatitis C patients after a sustained virological response achieved with direct-acting antivirals. METHODS Transient elastography with controlled attenuation parameter (CAP) was used to assess hepatic steatosis post-sustained virological response (SVR); the CAP technology was not available in the United States at study initiation. Liver stiffness/fibrosis was measured before and 47 wk after treatment completion. Patients with genotype 3 and patients with cirrhosis were excluded. RESULTS One hundred and one patients were included in the study. Post-SVR there were decreases from baseline in alanine aminotransferase (ALT) (63.1 to 17.8 U/L), aspartate aminotransferase (51.8 to 21.5 U/L) and fibrosis score (7.4 to 6.1 kPa) (P steatosis on CAP; of these, 6.25% had advanced fibrosis. Patients with steatosis had higher body mass index (29.0 vs 26.1 kg/m2), glucose (107.8 vs 96.6 mg/dL), ALT (20.4 vs 15.3 mg/dL), CAP score (296.3 vs 212.4 dB/m) and fibrosis score (7.0 vs 5.3 kPa); P steatosis had change in fibrosis score post-SVR (7.7 kPa vs 7.0 kPa and 7.0 kPa vs 5.3 kPa); alternatively, (P steatosis continued to have clinically significant stiffness (≥ 7 kPa). CONCLUSION Fatty liver is very common in hepatitis C virus (HCV) patients post-SVR. These patients continue to have elevated mean fibrosis score (≥ 7 kPa) compared to those without fatty liver; some have advanced fibrosis. Long term follow up is needed to assess steatosis and fibrosis in HCV patients post-SVR. PMID:29568207

  20. A novel radiation responsive cis-acting element regulates gene induction and mediates tissue injury

    Hallahan, Dennis E.; Virudachalam, Subbulakshmi; Kuchibahtla, Jaya

    1997-01-01

    containing binding domains for the transcription factors AP-1 and Ets. This DNA sequence (TGCCTCAGTTTCCC) is similar to antioxidant responsive element. X-ray- mediated transcriptional activation of the 5' regulatory region of ICAM-1 required the antioxidant responsive element (ARE). Electrophoretic mobility shift analysis of nuclear proteins from irradiated endothelial cells incubated with the ARE binding domain (5'-GCTGCTGCCTCAGTTTCCC-3') showed increased protein-DNA complexes at 60 and 120 minutes after irradiation. Conclusions: 1) ICAM induction in irradiated tissue occurs in the microvascular endothelium. 2) ICAM expression contributes to the pathogenesis of radiation-mediated tissue injury and the ICAM knockout serves as a model for the study of the pathogenesis of tissue injury. 3) ICAM expression is regulated by a novel radiation-inducible cis-acting element that has homology to previously identified antioxidant responsive elements

  1. Local Responses to National Policy: The Contrasting Experiences of Two Midlands Cities to the Academies Act 2010

    Smith, Penny; Abbott, Ian

    2014-01-01

    Drawing on data from a series of semi-structured interviews this article reports on findings from a research project focusing on the responses of two local authorities and their secondary schools to the Academies Act 2010. The article considers the background and the development of the education system in both localities. It goes on to focus on…

  2. 76 FR 53452 - Clean Air Act Operating Permit Program; Response to Petition To Reopen the 2001 Title V Permit...

    2011-08-26

    ... ENVIROMENTAL PROTECTION AGENCY [FRL-9457-3 ] Clean Air Act Operating Permit Program; Response to Petition To Reopen the 2001 Title V Permit for Reliant Portland Generating Station, Upper Mount Bethel Township, Northampton County, PA AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of action...

  3. The U.S. Forest Service and its responsibilities under the national environmental policy act: a work design problem

    Matthew Auer; Kenneth Richards; David N. Seesholtz; Burnell Fischer; Christian Freitag; Joshua. Grice

    2011-01-01

    The U.S. Forest Service’s responsibilities under the National Environmental Policy Act entail a wide range of activities including scoping, scientific analysis, social and economic analysis, managing public input and involvement, media relations, regulatory analysis, and litigation. These myriad duties raise several important organizational and management questions....

  4. Baseline adiponectin levels do not influence the response to pioglitazone in ACT NOW.

    Tripathy, Devjit; Clement, Stephen C; Schwenke, Dawn C; Banerji, MaryAnn; Bray, George A; Buchanan, Thomas A; Gastaldelli, Amalia; Henry, Robert R; Kitabchi, Abbas E; Mudaliar, Sunder; Ratner, Robert E; Stentz, Frankie B; Musi, Nicolas; Reaven, Peter D; DeFronzo, Ralph A

    2014-06-01

    Plasma adiponectin levels are reduced in type 2 diabetes mellitus (T2DM) and other insulin-resistant states. We examined whether plasma adiponectin levels at baseline and after pioglitazone treatment in impaired glucose tolerance (IGT) subjects were associated with improved insulin sensitivity (SI) and glucose tolerance status. A total of 602 high-risk IGT subjects in ACT NOW were randomized to receive pioglitazone or placebo with a median follow-up of 2.4 years. Pioglitazone reduced IGT conversion to diabetes by 72% in association with improved β-cell function by 64% (insulin secretion/insulin resistance index) and increased tissue sensitivity by 88% (Matsuda index). In pioglitazone-treated subjects, plasma adiponectin concentration increased threefold from 13 ± 0.5 to 38 ± 2.5 μg/mL (P < 0.001) and was strongly correlated with the improvement in SI (r = 0.436, P < 0.001) and modestly correlated with glucose area under the curve during oral glucose tolerance test (r = 0.238, P < 0.005) and insulin secretion/insulin resistance index (r = 0.306, P < 0.005). The increase in adiponectin was a strong predictor of reversion to normal glucose tolerance and prevention of T2DM. In the placebo group, plasma adiponectin did not change and was not correlated with changes in glucose levels. There was an inverse association between baseline plasma adiponectin concentration and progression to diabetes in the placebo group but not in the pioglitazone group. Baseline adiponectin does not predict the response to pioglitazone. The increase in plasma adiponectin concentration after pioglitazone therapy in IGT subjects is strongly related to improved glucose tolerance status and enhanced tissue sensitivity to insulin. © 2014 by the American Diabetes Association.

  5. Waste minimization concepts applied to oil spill response or (integrating the Pollution Prevention Act of 1990 with the Oil Pollution Act of 1990)

    Ferriere, D.V.

    1993-01-01

    As of July 23, 1993 the National Contingency Plan (NCP) for oil spills and hazardous substance releases (40CFR300) is being revised to comply with Oil Pollution Act 1990 (OPA '90) requirements. An important OPA '90 development is the creation of localized groups to write Area Contingency Plans (ACPs). During the ACP process many political, economical, and environmental issues will be addressed by representatives from several local, county, state, federal agencies and industry. Some of the difficulty decision makers must face is weighing environmental tradeoffs considering socio-economic aspects and determining what is the most effective ecologically sensible/environmental protection oil spill response strategy. Ideally, the NCP is designed as a democratic process providing a voice to all effected parties on how to best protect the environment, natural resources, and commercial resources. However, practice has shown successful emergency response is best handled when a single focal point of command, commonly referred to as incident command, has an agreed upon response agenda. The following will address the need for decision makers and contingency planners to at least address waste minimization principles, if not make it their primary focus, when developing and executing the oil spill response plan

  6. Fatty liver in hepatitis C patients post-sustained virological response with direct-acting antivirals.

    Noureddin, Mazen; Wong, Micaela M; Todo, Tsuyoshi; Lu, Shelly C; Sanyal, Arun J; Mena, Edward A

    2018-03-21

    To determine steatosis and fibrosis prevalence in hepatitis C patients after a sustained virological response achieved with direct-acting antivirals. Transient elastography with controlled attenuation parameter (CAP) was used to assess hepatic steatosis post-sustained virological response (SVR); the CAP technology was not available in the United States at study initiation. Liver stiffness/fibrosis was measured before and 47 wk after treatment completion. Patients with genotype 3 and patients with cirrhosis were excluded. One hundred and one patients were included in the study. Post-SVR there were decreases from baseline in alanine aminotransferase (ALT) (63.1 to 17.8 U/L), aspartate aminotransferase (51.8 to 21.5 U/L) and fibrosis score (7.4 to 6.1 kPa) ( P < 0.05). Post-SVR, 48 patients (47.5%) had steatosis on CAP; of these, 6.25% had advanced fibrosis. Patients with steatosis had higher body mass index (29.0 vs 26.1 kg/m 2 ), glucose (107.8 vs 96.6 mg/dL), ALT (20.4 vs 15.3 mg/dL), CAP score (296.3 vs 212.4 dB/m) and fibrosis score (7.0 vs 5.3 kPa); P < 0.05. Interestingly, compared to baseline, both patients with and without steatosis had change in fibrosis score post-SVR (7.7 kPa vs 7.0 kPa and 7.0 kPa vs 5.3 kPa); alternatively, ( P < 0.05) and therefore patients with steatosis continued to have clinically significant stiffness (≥ 7 kPa). Fatty liver is very common in hepatitis C virus (HCV) patients post-SVR. These patients continue to have elevated mean fibrosis score (≥ 7 kPa) compared to those without fatty liver; some have advanced fibrosis. Long term follow up is needed to assess steatosis and fibrosis in HCV patients post-SVR.

  7. 75 FR 42363 - Public Health Security and Bioterrorism Preparedness and Response Act of 2002; Biennial Review...

    2010-07-21

    ... be e-mailed to: [email protected] . FOR FURTHER INFORMATION CONTACT: Robbin Weyant, Director..., Atlanta, GA 30333. Telephone: (404) 718- 2000. SUPPLEMENTARY INFORMATION: The Bioterrorism Act requires... to the Select Agent regulations (42 CFR Part 73) to implement a tiering and/or stratification schema...

  8. Flexible Response: Executive Federalism and the No Child Left Behind Act of 2001

    Shelly, Bryan

    2012-01-01

    The federal government promised that it would limit waiver grants to states for the No Child Left Behind Act of 2001 (NCLB). It largely kept that promise, but states did gain significant flexibility through amendments to accountability plans. OLS model estimates showed that larger, more affluent, and more Republican states submitted more amendment…

  9. Global Warming Responses at the Primary Secondary Interface: 1. Students' Beliefs and Willingness to Act

    Skamp, Keith; Boyes, Eddie; Stannistreet, Martin

    2009-01-01

    Using survey methodology, students' beliefs, and willingness to act, about 16 specific actions related to global warming are compared across the primary secondary interface. More primary students believed in the effectiveness of most actions to reduce global warming and were willing to take those actions. In general there was a disparity between…

  10. 78 FR 73525 - Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) or Superfund...

    2013-12-06

    ... Conservation and Recovery Act (RCRA). Many state programs also offer accompanying financial incentive programs... states and tribes that have the management and administrative capacity within their government required... identify the institutional controls relied on in the remedy and include relevant information concerning the...

  11. Economic consequences of the German environmental liability act: Capital market response for the chemical industry

    Bartsch, Elga

    1997-01-01

    The Environmental Liability Act (Umwelthaftungsgesetz) enacted January 1, 1991 is claimed to have substantially tightened the environmental liability regime in Germany. The economic consequences of the amendment of the German environmental liability legislation initiated by the Sandoz accident are investigated for a portfolio of firms in the chemical industry. By means of an event study it is determined whether the UmweltHG has led to a revision of expectations regarding the profitability of ...

  12. The Thrift Industry and the Community Reinvestment Act: Assessing the Cost of Social Responsibility

    Donald F. Vitaliano; Gregory Stella

    2003-01-01

    A stochastic frontier cost function indicates that the annual cost of complying with the anti-redlining Community Reinvestment Act (CRA) is $171,000 per thrift institution, roughly 2.3 percent of variable costs. But compliance cost is significantly less than the estimated 21 percent cost inefficiency. Based on published estimates of the incremental number of mortgage loans induced by CRA, the marginal cost is $38,000 per loan. The regulations whose compliance cost is estimated apply to about ...

  13. Benevolent sexist ideology attributed to an abusive partner decreases women's active coping responses to acts of sexual violence.

    Durán, Mercedes; Moya, Miguel; Megías, Jesús L

    2014-05-01

    This article describes three studies in which we explored the influence of the sexist ideology attributed to the perpetrator on women's responses to hypothetical acts of sexual assault perpetrated by male intimate partners. In Study 1 (n = 83), college women read three sexual assault scenarios in the context of an intimate relationship. The male partner's sexist ideology (benevolent, hostile, or control) was manipulated within participants. Women showed less active responses when the partner had been described as a benevolent sexist man. This effect was replicated in Study 2 (n = 103), which showed a relationship between women's less active responses and the belief that benevolent sexist men are very attracted to and interested in their partners. Study 3 (n = 130) demonstrated experimentally that women's responses are less active when they are exposed to information that indicates that the perpetrator is both high in benevolent sexism and highly attracted to his victim than when the latter information is not provided. Results suggest that sexist ideology and particularly benevolent sexism-attributed to the perpetrator in this case-is highly important in women's reactions to acts of sexual violence perpetrated by male intimate partners.

  14. Applicability of Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) to releases of radioactive substances

    Miller, S.R.

    1987-01-01

    The Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA), commonly called Superfund, provided a $1.6 billion fund (financed by a tax on petrochemical feedstocks and crude oil and by general revenues) for the cleanup of releases of hazardous substances, including source, special nuclear or byproduct material, and other radioactive substances, from mostly inactive facilities. The US Environmental Protection Agency (EPA) is authorized to require private responsible parties to clean up releases of hazardous substances, or EPA, at its option, may undertake the cleanup with monies from the Fund and recover the monies through civil actions brought against responsible parties. CERCLA imposes criminal penalties for noncompliance with its reporting requirements. This paper will overview the key provisions of CERCLA which apply to the cleanup of radioactive materials

  15. Application of Clean Water (CWA) Section 404 compensatory wetland mitigation under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA)

    Abbott, D.J.; Straub, C.A.

    1994-01-01

    Pursuant to Section 404 of the Clean Water Act (CWA), activities resulting in the discharge of dredge or fill material into waters of the US, including wetlands, require permit authorization from the US Army Corps of Engineers (ACOE). As part of the Section 404 permitting process, compensatory wetland mitigation in the form of wetland enhancement, restoration, or construction may be required to off-set impacts sustained under a Section 404 permit. Under normal circumstances, compensatory mitigation is a relatively straight forward process; however, issues associated with mitigation become more complex at sites undergoing remediation under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), because on-site response/remedial actions involving dredged and fill material are not subject to the formal Section 404 permitting process. These actions are conducted in accordance with the substantive permitting requirements of the ACOE's Nationwide and individual permitting programs. Wetland mitigatory requirements are determined through application of the US Environmental Protection Agency's (USEPA's) 040(b) (1) Guidelines promulgated in 40 CFR Part 230 and are implemented through compliance with substantive permitting requirements during the conduct of response/remedial actions. A programmatic approach for implementing wetland mitigatory requirements is being developed at a former US Department of Energy (DOE) uranium refinery undergoing CERCLA remediation in southwestern Ohio. The approach is designed to define the regulatory mechanism that will be used to integrate CWA driven wetland mitigatory requirements into the CERCLA process

  16. Matters of Responsibility for Marine Pollution under the Legislation of the Russian Federation. (Review of the Main Legislative Acts)

    Kolodkin, A.L.; Kulistikova, O.V.; Mokhova, E.M.

    1997-12-31

    International Northern Sea Route Programme, INSROP, is a five-year multilateral research programme. The main phase of the programme started in 1993. The three principal cooperating partners are research institutes in Russia, Japan and Norway. The aim of INSROP is to build up a knowledge base to provide foundation for a long-term planning and decision making by state agencies and private companies etc., for purposes of promoting rational decision making on the use of the Northern Sea route for transit and regional development. This report reviews the main legislative acts of former USSR and the Russian Federation, systematized by the responsibility types: (1) civil (property), (2) criminal and (3) administrative. It also discusses the issues of responsibility for marine pollution in accordance with the draft of the new Merchant Shipping Code of the Russian Federation, which contains sections on liability for damage caused by oil pollution from ships or by transport of hazardous and noxious substances by sea. 18 refs.

  17. Simulating Nonmodel-Fitting Responses in a CAT Environment. ACT Research Report Series 98-10.

    Yi, Qing; Nering, Michael L.

    This study developed a model to simulate nonmodel-fitting responses in a computerized adaptive testing (CAT) environment, and to examine the effectiveness of the model. The underlying idea was to simulate examinees' test behaviors realistically. This study simulated a situation in which examinees are exposed to or are coached on test items before…

  18. Assessment of the response of spent fuel transports to malevolent acts

    Sandoval, R.P.

    1983-01-01

    This paper describes the results of a program conducted at Sandia National Laboratories (SNL) for the US Department of Energy to provide an experimental data base for more accurately assessing the radiological consequences from a hypothetical sabotage attack on a spent fuel shipping cask. The primary objectives of the program were limited to: (1) evaluating the effectiveness of selected high explosive devices (HED) in breaching full-size spent fuel casks, (2) quantifying and characterizing relevant aerosol properties of the released fuel, and (3) using the resulting experimental data to evaluate the radiological health consequences resulting from a hypothetical sabotage attack on a spent fuel shipping cask in a densely populated area. Subscale and full-scale experiments in conjunction with an analytical modeling study were performed to meet the programmatic objectives. The data from this program indicate that the Urban Studies greatly overestimated the impact of malevolent acts directed at spent fuel casks in urban environs. From that standpoint this work could be the basis of additional regulatory revisions of the NRC physical protection requirements. In a larger sense this work can also be the basis of more credible worst case analyses since it defines the actual result of an event which is well beyond any expectations of cask failures in accident environments. 5 references

  19. Developments on drug discovery and on new therapeutics: highly diluted tinctures act as biological response modifiers.

    de Oliveira, Carolina C; Abud, Ana Paula R; de Oliveira, Simone M; Guimarães, Fernando de S F; de Andrade, Lucas F; Di Bernardi, Raffaello P; Coletto, Ediely L de O; Kuczera, Diogo; Da Lozzo, Eneida J; Gonçalves, Jenifer P; Trindade, Edvaldo da S; Buchi, Dorly de F

    2011-10-26

    In the search for new therapies novel drugs and medications are being discovered, developed and tested in laboratories. Highly diluted substances are intended to enhance immune system responses resulting in reduced frequency of various diseases, and often present no risk of serious side-effects due to its low toxicity. Over the past years our research group has been investigating the action of highly diluted substances and tinctures on cells from the immune system. We have developed and tested several highly diluted tinctures and here we describe the biological activity of M1, M2, and M8 both in vitro in immune cells from mice and human, and in vivo in mice. Cytotoxicity, cytokines released and NF-κB activation were determined after in vitro treatment. Cell viability, oxidative response, lipid peroxidation, bone marrow and lymph node cells immunophenotyping were accessed after mice in vivo treatment. None of the highly diluted tinctures tested were cytotoxic to macrophages or K562. Lipopolysaccharide (LPS)-stimulated macrophages treated with all highly diluted tinctures decreased tumour necrosis factor alpha (TNF-α) release and M1, and M8 decreased IFN-γ production. M1 has decreased NF-κB activity on TNF-α stimulated reporter cell line. In vivo treatment lead to a decrease in reactive oxygen species (ROS), nitric oxide (NO) production was increased by M1, and M8, and lipid peroxidation was induced by M1, and M2. All compounds enhanced the innate immunity, but M1 also augmented acquired immunity and M2 diminished B lymphocytes, responsible to acquired immunity. Based on the results presented here, these highly diluted tinctures were shown to modulate immune responses. Even though further investigation is needed there is an indication that these highly diluted tinctures could be used as therapeutic interventions in disorders where the immune system is compromised.

  20. Developments on drug discovery and on new therapeutics: highly diluted tinctures act as biological response modifiers

    de Oliveira Carolina C

    2011-10-01

    Full Text Available Abstract Background In the search for new therapies novel drugs and medications are being discovered, developed and tested in laboratories. Highly diluted substances are intended to enhance immune system responses resulting in reduced frequency of various diseases, and often present no risk of serious side-effects due to its low toxicity. Over the past years our research group has been investigating the action of highly diluted substances and tinctures on cells from the immune system. Methods We have developed and tested several highly diluted tinctures and here we describe the biological activity of M1, M2, and M8 both in vitro in immune cells from mice and human, and in vivo in mice. Cytotoxicity, cytokines released and NF-κB activation were determined after in vitro treatment. Cell viability, oxidative response, lipid peroxidation, bone marrow and lymph node cells immunophenotyping were accessed after mice in vivo treatment. Results None of the highly diluted tinctures tested were cytotoxic to macrophages or K562. Lipopolysaccharide (LPS-stimulated macrophages treated with all highly diluted tinctures decreased tumour necrosis factor alpha (TNF-α release and M1, and M8 decreased IFN-γ production. M1 has decreased NF-κB activity on TNF-α stimulated reporter cell line. In vivo treatment lead to a decrease in reactive oxygen species (ROS, nitric oxide (NO production was increased by M1, and M8, and lipid peroxidation was induced by M1, and M2. All compounds enhanced the innate immunity, but M1 also augmented acquired immunity and M2 diminished B lymphocytes, responsible to acquired immunity. Conclusions Based on the results presented here, these highly diluted tinctures were shown to modulate immune responses. Even though further investigation is needed there is an indication that these highly diluted tinctures could be used as therapeutic interventions in disorders where the immune system is compromised.

  1. Feedforward responses of transversus abdominis are directionally specific and act asymmetrically: implications for core stability theories.

    Allison, Garry T; Morris, Sue L; Lay, Brendan

    2008-05-01

    Experimental laboratory study supplemented with a repeated case study. To examine bilateral muscle activity of the deep abdominals in response to rapid arm raising, specifically to examine the laterality and directional specificity of feedforward responses of the transversus abdominis (TrA). Based on the feedforward responses of trunk muscles during rapid arm movements, authors have concluded that the deep trunk muscles have different control mechanisms compared to the more superficial muscles. It has been proposed that deep trunk muscles such as TrA contribute substantially to the stability of the lumbar spine and that this is achieved through simultaneous bilateral feedforward activation. These inferences are based on unilateral fine-wire electromyographic (EMG) data and there are limited investigations of bilateral responses of the TrA during unilateral arm raising. Bilateral fine-wire and surface EMG data from the anterior deltoid, TrA, obliquus internus (OI), obliquus externus, biceps femoris, erector spinae, and rectus abdominis during repeated arm raises were recorded at 2 kHz. EMG signal linear envelopes were synchronized to the onset of the anterior deltoid. A feedforward window was defined as the period up to 50 ms after the onset of the anterior deltoid, and paired onsets for bilateral muscles were plotted for both left and right arm movements. Trunk muscles from the group data demonstrated differences between sides (laterality), which were systematically altered when alternate arms were raised (directional specificity). This was clearly evident for the TrA but less obvious for the erector spinae. The ipsilateral biceps femoris and obliquus externus, and contralateral OI and TrA, were activated earlier than the alternate side for both right and left arm movements. This was a consistent pattern over a 7-year period for the case study. Data for the rectus abdominis derived from the case study demonstrated little laterality or directionally specific

  2. Code Lavender: Cultivating Intentional Acts of Kindness in Response to Stressful Work Situations.

    Davidson, Judy E; Graham, Patricia; Montross-Thomas, Lori; Norcross, William; Zerbi, Giovanna

    Providing healthcare can be stressful. Gone unchecked, clinicians may experience decreased compassion, and increased burnout or secondary traumatic stress. Code Lavender is designed to increase acts of kindness after stressful workplace events occur. To test the feasibility of providing Code Lavender. After stressful events in the workplace, staff will provide, receive, and recommend Code Lavender to others. The provision of Code Lavender will improve Professional Quality of Life Scale (ProQoL) scores, general job satisfaction, and feeling cared for in the workplace. Pilot program testing and evaluation. Staff and physicians on four hospital units were informed of the Code Lavender kit availability, which includes words of comfort, chocolate, lavender essential oil, and employee health referral information. Feasibility data and ProQoL scores were collected at baseline and three months. At baseline, 48% (n = 164) reported a stressful event at work in the last three months. Post-intervention, 51% reported experiencing a stressful workplace event, with 32% receiving a Code Lavender kit from their co-workers as a result (n = 83). Of those who received the Code Lavender intervention; 100% found it helpful, and 84% would recommend it to others. No significant changes were demonstrated before and after the intervention in ProQoL scores or job satisfaction, however the emotion of feeling cared-for improved. Results warrant continuation and further dissemination of Code Lavender. Investigators have received requests to expand the program implying positive reception of the intervention. Additional interventions are needed to overcome workplace stressors. A more intense peer support program is being tested. Copyright © 2017. Published by Elsevier Inc.

  3. Cyclic AMP Receptor Protein Acts as a Transcription Regulator in Response to Stresses in Deinococcus radiodurans.

    Su Yang

    Full Text Available The cyclic AMP receptor protein family of transcription factors regulates various metabolic pathways in bacteria, and also play roles in response to environmental changes. Here, we identify four homologs of the CRP family in Deinococcus radiodurans, one of which tolerates extremely high levels of oxidative stress and DNA-damaging reagents. Transcriptional levels of CRP were increased under hydrogen peroxide (H2O2 treatment during the stationary growth phase, indicating that CRPs function in response to oxidative stress. By constructing all CRP single knockout mutants, we found that the dr0997 mutant showed the lowest tolerance toward H2O2, ultraviolet radiation, ionizing radiation, and mitomycin C, while the phenotypes of the dr2362, dr0834, and dr1646 mutants showed slight or no significant differences from those of the wild-type strain. Taking advantage of the conservation of the CRP-binding site in many bacteria, we found that transcription of 18 genes, including genes encoding chromosome-partitioning protein (dr0998, Lon proteases (dr0349 and dr1974, NADH-quinone oxidoreductase (dr1506, thiosulfate sulfurtransferase (dr2531, the DNA repair protein UvsE (dr1819, PprA (dra0346, and RecN (dr1447, are directly regulated by DR0997. Quantitative real-time polymerase chain reaction (qRT-PCR analyses showed that certain genes involved in anti-oxidative responses, DNA repair, and various cellular pathways are transcriptionally attenuated in the dr0997 mutant. Interestingly, DR0997 also regulate the transcriptional levels of all CRP genes in this bacterium. These data suggest that DR0997 contributes to the extreme stress resistance of D. radiodurans via its regulatory role in multiple cellular pathways, such as anti-oxidation and DNA repair pathways.

  4. Hydrogen peroxide and polyamines act as double edged swords in plant abiotic stress responses

    Kamala Gupta

    2016-09-01

    Full Text Available The specific genetic changes through which plants adapt to the multitude of environmental stresses are possible because of the molecular regulations in the system. These intricate regulatory mechanisms once unveiled will surely raise interesting questions. Polyamines and hydrogen peroxide have been suggested to be important signalling molecules during biotic and abiotic stresses. Hydrogen peroxide plays a versatile role from orchestrating physiological processes to stress response. It helps to achieve acclimatization and tolerance to stress by coordinating intra-cellular and systemic signalling systems. Polyamines, on the other hand, are low molecular weight polycationic aliphatic amines, which have been implicated in various stress responses. It is quite interesting to note that both hydrogen peroxide and polyamines have a fine line of inter-relation between them since the catabolic pathways of the latter releases hydrogen peroxide. In this review we have tried to illustrate the roles and their multifaceted functions of these two important signalling molecules based on current literature. This review also highlights the fact that over accumulation of hydrogen peroxide and polyamines can be detrimental for plant cells leading to toxicity and pre-mature cell death.

  5. Hydrogen Peroxide and Polyamines Act as Double Edged Swords in Plant Abiotic Stress Responses.

    Gupta, Kamala; Sengupta, Atreyee; Chakraborty, Mayukh; Gupta, Bhaskar

    2016-01-01

    The specific genetic changes through which plants adapt to the multitude of environmental stresses are possible because of the molecular regulations in the system. These intricate regulatory mechanisms once unveiled will surely raise interesting questions. Polyamines and hydrogen peroxide have been suggested to be important signaling molecules during biotic and abiotic stresses. Hydrogen peroxide plays a versatile role from orchestrating physiological processes to stress response. It helps to achieve acclimatization and tolerance to stress by coordinating intra-cellular and systemic signaling systems. Polyamines, on the other hand, are low molecular weight polycationic aliphatic amines, which have been implicated in various stress responses. It is quite interesting to note that both hydrogen peroxide and polyamines have a fine line of inter-relation between them since the catabolic pathways of the latter releases hydrogen peroxide. In this review we have tried to illustrate the roles and their multifaceted functions of these two important signaling molecules based on current literature. This review also highlights the fact that over accumulation of hydrogen peroxide and polyamines can be detrimental for plant cells leading to toxicity and pre-mature cell death.

  6. A novel branched chain amino acids responsive transcriptional regulator, BCARR, negatively acts on the proteolytic system in Lactobacillus helveticus.

    Taketo Wakai

    Full Text Available Transcriptional negative regulation of the proteolytic system of Lactobacillus helveticus CM4 in response to amino acids seems to be very important for the control of antihypertensive peptide production; however, it remains poorly understood. A 26-kDa protein with N-terminal cystathionine β-synthase domains (CBS domain protein, which seems to be involved in the regulatory system, was purified by using a DNA-sepharose bound 300-bp DNA fragment corresponding to the upstream regions of the six proteolytic genes that are down-regulated by amino acids. The CBS domain protein bound to a DNA fragment corresponding to the region upstream of the pepV gene in response to branched chain amino acids (BCAAs. The expression of the pepV gene in Escherichia coli grown in BCAA-enriched medium was repressed when the CBS domain protein was co-expressed. These results reveal that the CBS domain protein acts as a novel type of BCAA-responsive transcriptional regulator (BCARR in L. helveticus. From comparative analysis of the promoter regions of the six proteolysis genes, a palindromic AT-rich motif, 5'-AAAAANNCTWTTATT-3', was predicted as the consensus DNA motif for the BCARR protein binding. Footprint analysis using the pepV promotor region and gel shift analyses with the corresponding short DNA fragments strongly suggested that the BCARR protein binds adjacent to the pepV promoter region and affects the transcription level of the pepV gene in the presence of BCAAs. Homology search analysis of the C-terminal region of the BCARR protein suggested the existence of a unique βαββαβ fold structure that has been reported in a variety of ACT (aspartate kinase-chorismate mutase-tyrA domain proteins for sensing amino acids. These results also suggest that the sensing of BCAAs by the ACT domain might promote the binding of the BCARR to DNA sequences upstream of proteolysis genes, which affects the gene expression of the proteolytic system in L. helveticus.

  7. Response of a quick acting valve for underground nuclear blast containment

    Bennett, M.D.; Curry, W.H.

    1979-10-01

    The motion of a large, sliding piston impelled by the action of an inert gas at high pressure is modeled mathematically by assuming that the working fluid behaves as an ideal gas and that a steady flow process prevails. It is found from numerical solutions of the governing equations that as the aperture, which connects the gas reservoir and receiver, is enlarged, a critical size is reached, beyond which the valve response remains essentially independent of any further increases in the aperture dimension. With supercritical apertures and using, for example, 1.5 ft 3 of 15-kpsi nitrogen as the driver gas, the estimated time for a 2.6-ton piston to travel across a 6-ft wide tunnel is 31 milliseconds. Gases that have the largest number of molecular degrees of freedom theoretically impart the most motive power

  8. Act No 6453 of 17th October, 1977 on civil liability for nuclear damage and criminal responsibility for acts relating to nuclear activities, and other provisions

    1978-01-01

    This Act was published on 17 October 1977. It is based to a great extent on the provisions of the Vienna Convention on Civil Liability for Nucler Damage of 21 May 1963. Under the Act the operator of a nuclear installation is exclusively liable regardless of fault for compensation of nuclear damage due to a nuclear incident. This exclusive liability is limited to an amount equal to 1,500,000 Treasury Bonds and the operator must take out and maintain insurance or other financial security to cover his liability. The Federative Government will guarantee, up to the prescribed limit, payment of compensation for nuclear damage where it is acknowledged that the operator's liability is involved. As regards apportionment of compensation, persons are granted priority over property. This Act is original in that it contains provisions on criminal liability with penalties ranging from two to ten years imprisonment. (NEA) [fr

  9. Learning to Act Like a Lawyer: A Model Code of Professional Responsibility for Law Students

    David M. Tanovich

    2009-02-01

    Full Text Available Law students are the future of the legal profession. How well prepared are they when they leave law school to assume the professional and ethical obligations that they owe themselves, the profession and the public? This question has led to a growing interest in Canada in the teaching of legal ethics. It is also led to a greater emphasis on the development of clinical and experiential learning as exemplified in the scholarship and teaching of Professor Rose Voyvodic. Less attention, however, has been placed on identifying the general ethical responsibilities of law students when not working in a clinic or other legal context. This can be seen in the presence of very few Canadian articles exploring the issue, and more significantly, in the paucity of law school discipline policies or codes of conduct that set out the professional obligations owed by law students. This article develops an idea that Professor Voyvodic and I talked about on a number of occasions. It argues that all law schools should have a code of conduct which is separate and distinct from their general University code and which resembles, with appropriate modifications, the relevant set of rules of professional responsibility law students will be bound by when called to the Bar. A student code of conduct which educates law students about their professional obligations is an important step in deterring such conduct while in law school and preparing students for ethical practice. The idea of a law school code of professional responsibility raises a number of questions. Why is it necessary for law schools to have their own student code of conduct? The article provides a threefold response. First, law students are members of the legal profession and a code of conduct should reflect this. Second, it must be relevant and comprehensive in order to ensure that it can inspire students to be ethical lawyers. And, third, as a practical matter, the last few years have witnessed a number of

  10. On the relative importance of loads acting on a floating verticalaxis wind turbine system when evaluating the global system response

    Collu, Maurizio; Borg, Michael; Manuel, Lance

    2016-01-01

    of the VAWT aerodynamic forces, the platform hydrodynamic forces, and the mooring forces. The results help evaluate the relative importance of hydrodynamic with respect to aerodynamic forces, depending on the loading condition. A deeper insight into the aerodynamic forces is provided, which shows the impact...... their potential advantages. Due to the substantial differences between HAWT and VAWT systems, analysis procedures employed for a floating HAWT analyses cannot be extended to use for floating VAWT systems. Here, the main aim is to provide a systematic analysis and comparison of the forces acting on a reference...... by the OC4-Phase II semisubmersible. Using the coupled model of dynamics for VAWT "FloVAWT", the global response of the system is estimated for a set of load cases, allowing the assessment of the contributions of individual force components. In particular, the simulations allow us to assess the impact...

  11. Near-UV radiation acts as a beneficial factor for physiological responses in cucumber plants.

    Mitani-Sano, Makiko; Tezuka, Takafumi

    2013-11-05

    Effects of near-UV radiation on the growth and physiological activity of cucumber plants were investigated morphologically, physiologically and biochemically using 3-week-old seedlings grown under polyvinyl chloride films featuring transmission either above 290 nm or above 400 nm in growth chambers. The hypocotyl length and leaf area of cucumber seedlings were reduced but the thickness of leaves was enhanced by near-UV radiation, due to increased upper/lower epidermis thickness, palisade parenchyma thickness and volume of palisade parenchyma cells. Photosynthetic and respiratory activities were also promoted by near-UV radiation, associated with general enhancement of physiological/biochemical responses. Particularly, metabolic activities in the photosynthetic system of chloroplasts and the respiratory system of mitochondria were analyzed under the conditions of visible light with and without near-UV radiation. For example, the activities of NAD(P)-dependent enzymes such as glyceraldehyde-3-phosphate dehydrogenase (G3PDH) in chloroplasts and isocitrate dehydrogenase (ICDH) in mitochondria were elevated, along with levels of pyridine nucleotides (nicotinamide coenzymes) [NAD(H) and NADP(H)] and activity of NAD kinase (NADP forming enzyme). Taken together, these data suggest that promotion of cucumber plant growth by near-UV radiation involves activation of carbon and nitrogen metabolism in plants. The findings of this research showed that near-UV radiation reaching the Earth's surface is a beneficial factor for plant growth. Copyright © 2013. Published by Elsevier B.V.

  12. Can urinary exosomes act as treatment response markers in prostate cancer?

    Tabi Zsuzsanna

    2009-01-01

    Full Text Available Abstract Background Recently, nanometer sized vesicles (termed exosomes have been described as a component of urine. Such vesicles may be a useful non-invasive source of markers in renal disease. Their utility as a source of markers in urological cancer remains unstudied. Our aim in this study was to investigate the feasibility and value of analysing urinary exosomes in prostate cancer patients undergoing standard therapy. Methods Ten patients (with locally advanced PCa provided spot urine specimens at three time points during standard therapy. Patients received 3–6 months neoadjuvant androgen deprivation therapy prior to radical radiotherapy, comprising a single phase delivering 55 Gy in 20 fractions to the prostate and 44 Gy in 20 fractions to the pelvic nodes. Patients were continued on adjuvant ADT according to clinical need. Exosomes were purified, and the phenotype compared to exosomes isolated from the prostate cancer cell line LNcaP. A control group of 10 healthy donors was included. Serum PSA was used as a surrogate treatment response marker. Exosomes present in urine were quantified, and expression of prostate markers (PSA and PSMA and tumour-associated marker 5T4 was examined. Results The quantity and quality of exosomes present in urine was highly variable, even though we handled all materials freshly and used methods optimized for obtaining highly pure exosomes. There was approx 2-fold decrease in urinary exosome content following 12 weeks ADT, but this was not sustained during radiotherapy. Nevertheless, PSA and PSMA were present in 20 of 24 PCa specimens, and not detected in healthy donor specimens. There was a clear treatment-related decrease in exosomal prostate markers in 1 (of 8 patient. Conclusion Evaluating urinary-exosomes remains difficult, given the variability of exosomes in urine specimens. Nevertheless, this approach holds promise as a non-invasive source of multiple markers of malignancy that could provide

  13. A new approach for determining phase response curves reveals that Purkinje cells can act as perfect integrators.

    Elena Phoka

    2010-04-01

    Full Text Available Cerebellar Purkinje cells display complex intrinsic dynamics. They fire spontaneously, exhibit bistability, and via mutual network interactions are involved in the generation of high frequency oscillations and travelling waves of activity. To probe the dynamical properties of Purkinje cells we measured their phase response curves (PRCs. PRCs quantify the change in spike phase caused by a stimulus as a function of its temporal position within the interspike interval, and are widely used to predict neuronal responses to more complex stimulus patterns. Significant variability in the interspike interval during spontaneous firing can lead to PRCs with a low signal-to-noise ratio, requiring averaging over thousands of trials. We show using electrophysiological experiments and simulations that the PRC calculated in the traditional way by sampling the interspike interval with brief current pulses is biased. We introduce a corrected approach for calculating PRCs which eliminates this bias. Using our new approach, we show that Purkinje cell PRCs change qualitatively depending on the firing frequency of the cell. At high firing rates, Purkinje cells exhibit single-peaked, or monophasic PRCs. Surprisingly, at low firing rates, Purkinje cell PRCs are largely independent of phase, resembling PRCs of ideal non-leaky integrate-and-fire neurons. These results indicate that Purkinje cells can act as perfect integrators at low firing rates, and that the integration mode of Purkinje cells depends on their firing rate.

  14. A New Conservative Cold Front? Democrat and Republican Responsiveness to the Passage of the Affordable Care Act

    Stephen L. Morgan

    2015-09-01

    Full Text Available Through an analysis of the 2004 through 2014 General Social Survey (GSS, this article demonstrates that the 2010 passage of the Affordable Care Act (ACA decreased support for spending on health among Democrats, Independents, and Republicans, contrary to the conjecture that a rigid partisanship equilibrium has taken hold among voters in the United States. Instead, only a partisan deflection is present, with spending preferences declining more for Republicans than for Democrats, and with Independents in between. Through supplemental analysis of the GSS panel data, as well as comparative analysis of other GSS items on national spending preferences, government responsibility, and confidence in leaders, this article also undermines support for an alternative explanation that cannot be entirely eliminated from plausibility, which is that the identified period effect that emerged in 2010 and persisted through 2014 is a response to the Great Recession and resulting deficit spending by the federal government. Implications for public opinion research are discussed, lending support to current models of thermostat effects and policy-specific political mood from the political science literature, which are informed by an older literature on weather fronts in public opinion that originated in the sociology literature.

  15. The United States Revised Uniform Anatomical Gift Act (2006: New challenges to balancing patient rights and physician responsibilities

    McGregor Joan L

    2007-09-01

    Full Text Available Abstract Advance health care directives and informed consent remain the cornerstones of patients' right to self-determination regarding medical care and preferences at the end-of-life. However, the effectiveness and clinical applicability of advance health care directives to decision-making on the use of life support systems at the end-of-life is questionable. The Uniform Anatomical Gift Act (UAGA has been revised in 2006 to permit the use of life support systems at or near death for the purpose of maximizing procurement opportunities of organs medically suitable for transplantation. Some states have enacted the Revised UAGA (2006 and a few of those have included amendments while attempting to preserve the uniformity of the revised Act. Other states have introduced the Revised UAGA (2006 for legislation and remaining states are likely to follow soon. The Revised UAGA (2006 poses challenges to the Patient Self Determination Act (PSDA embodied in advance health care directives and individual expression about the use of life support systems at the end-of-life. The challenges are predicated on the UAGA revising the default choice to presumption of donation intent and the use of life support systems to ensure medical suitability of organs for transplantation. The default choice trumps the expressed intent in an individual's advance health care directive to withhold and/or withdraw life support systems at the end-of-life. The Revised UAGA (2006 overrides advance directives on utilitarian grounds, which is a serious ethical challenge to society. The subtle progression of the Revised UAGA (2006 towards the presumption about how to dispose of one's organs at death can pave the way for an affirmative "duty to donate". There are at least two steps required to resolve these challenges. First, physicians and hospitals must fulfill their responsibilities to educate patients on the new legislations and document their preferences about the use of life support

  16. Implementation of Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Health Authority by the Agency for Toxic Substances and Disease Registry

    Siegel, M.R.

    1990-01-01

    The Superfund Amendments and Reauthorization Act (SARA) of 1986 greatly expanded the health authority of the Comprehensive Environmental Response, Compensation, and Liability Act. One of the federal agencies most affected by SARA is the Agency for Toxic Substances and Disease Registry (ATSDR) of the U.S. Public Health Service. Among other responsibilities, ATSDR was mandated to conduct health assessments within strict time frames for each site on or proposed for the U.S. Environmental Protection Agency's National Priorities List. The author will review ATSDR's efforts to address this new statutory mandate, especially for federal facilities, and will focus on different conceptual frameworks for implementing the health assessment program

  17. ATTRIBUTION OF CONDUCT TO A STATE-THE SUBJECTIVE ELEMENT OF THE INTERNATIONAL RESPONSIBILITY OT THE STATE FOR INTERNATIONALLY WRONGFUL ACTS

    FELICIA MAXIM

    2012-05-01

    Full Text Available In order to establish responsibility of states for internationally wrongful act, two elements are identified. First, the conduct in question must be attributable to the State under international law. Secondly, for responsibility to attach to the act of the State, the conduct must constitute a breach of an international legal obligation in force for that State at that time. For particular conduct to be characterized as an internationally wrongful act, it must first be attributable to the State. The State is a real organized entity, a legal person with full authority to act under international law. But to recognize this is not to deny the elementary fact that the State cannot act of itself. States can act only by and through their agents and representatives. In determining what constitutes an organ of a State for the purposes of responsibility, the internal law and practice of each State are of prime importance. The structure of the State and the functions of its organs are not, in general, governed by international law. It is a matter for each State to decide how its administration is to be structured and which functions are to be assumed by government. But while the State remains free to determine its internal structure and functions through its own law and practice, international law has a distinct role. Conduct is thereby attributed to the State as a subject of international law and not as a subject of internal law. The State as a subject of international law is held responsible for the conduct of all the organs, instrumentalities and officials which form part of its organization and act in that capacity, whether or not they have separate legal personality under its internal law.

  18. Advocating for School Psychologists in Response to the APA's Proposed "Model Act for State Licensure of Psychologists"

    Skalski, Anastasia Kalamaros

    2009-01-01

    On March 6, 2009, the APA Model Licensure Act Task Force released its second draft of the policy document known as the proposed "Model Act for State Licensure of Psychologists". This policy document serves as guidance to state legislatures for how they should set up their psychology licensing laws. The general expectations promoted in the model…

  19. DRIVING CORPORATE SOCIAL RESPONSIBILITY (CSR THROUGH THE COMPANIES ACT: AN OVERVIEW OF THE ROLE OF THE SOCIAL AND ETHICS COMMITTEE

    Henk J Kloppers

    2013-04-01

    policy requiring the implementation of socially responsible practices by the entire private sector is a necessity. Governments in general are increasingly beginning to view CSR as cost-effective means to enhance their sustainable development strategies, and as a part of their national competitiveness strategies to attract foreign direct investment. Given South Africa's history, legislation should be viewed as one of the main instruments enabling the Government to address the private sector's social, environmental and economic outreach activities.Against this background, this contribution identifies the regulations released in terms of the Companies Act 71 of 2008 in which the issue of the social and ethics committee is dealt with, as an important measure taken by Government to create a possible CSR platform. This contribution argues that the requirements regarding the creation of a social and ethics committee have the potential to embed the CSR notion in the corporate conscience. The aim of the contribution is to provide an overview of the role of the social and ethics committee, as envisaged by the Companies Regulations, 2011, as a potential driver of CSR.

  20. S. 1462: This Act may be cited as the Federal Nuclear Facilities Environmental Response Act. Introduced in the Senate of the United States, One Hundredth First Congress, First Session, August 1, 1989

    Anon.

    1989-01-01

    S. 1462 is a bill to create a Federal nuclear facility environmental response fund, to create and Office of Environmental Management and Remedial Action, to require the Secretary of Energy and the Administrator of the Environmental Protection Agency to cooperate with affected States and Indian tribes, to provide for research and development to address environmental problems at Federal nuclear facilities, and for other purposes. The basic purpose of the act is to provide and adequate, long-term source of funding for environmental restoration, decontamination, decommissioning, and management of Federal nuclear facilities and sites

  1. The draft on the act in the reorganisation of responsibility in nuclear waste management; Der Gesetzentwurf zur Neuordnung der Verantwortung in der kerntechnischen Entsorgung

    Raetzke, Christian [CONLAR Consulting on Nuclear Law and Regulation, Leipzig (Germany)

    2016-12-15

    The German Federal Cabinet passed the draft ''Act for the Reorganisation of Responsibility in Nuclear Waste Management''. The individual elements of the act shape an overall concept. The public sector, also assumes the interim storage of the waste in addition to the previous responsibility for final disposal of radioactive waste. Both tasks will be financed by a new public fund into which the operators pay their provisions. By paying an additional risk premium the operators can also exclude future margin requirements. This new concept is to be welcomed because it would lead to a structurally viable and sustainable solution for the final disposal of nuclear wastes, not withstanding many difficulties and partly uncertainties in detail.

  2. "Reforms Looked Really Good on Paper": Rural Food Service Responses to the Healthy, Hunger-Free Kids Act of 2010

    Cornish, Disa; Askelson, Natoshia; Golembiewski, Elizabeth

    2016-01-01

    Background: The Healthy, Hunger-Free Kids Act of 2010 (HHKA) required schools to make changes to meals provided to children. Rural school districts have limited resources, with increased obesity rates and local food insecurity. In this study we sought to understand the perceptions of rural food service directors and the barriers to implementing…

  3. Changes in heparin dose response slope during cardiac surgery: possible result in inaccuracy in predicting heparin bolus dose requirement to achieve target ACT.

    Ichikawa, Junko; Mori, Tetsu; Kodaka, Mitsuharu; Nishiyama, Keiko; Ozaki, Makoto; Komori, Makiko

    2017-09-01

    The substantial interpatient variability in heparin requirement has led to the use of a heparin dose response (HDR) technique. The accuracy of Hepcon-based heparin administration in achieving a target activated clotting time (ACT) using an HDR slope remains controversial. We prospectively studied 86 adult patients scheduled for cardiac surgery requiring cardiopulmonary bypass. The total dose of calculated heparin required for patient and pump priming was administered simultaneously to achieve a target ACT of 450 s for HDR on the Hepcon HMS system. Blood samples were obtained after the induction of anesthesia, at 3 min after heparin administration and after the initiation of CPB to measure kaolin ACT, HDR slope, whole-blood heparin concentration based on the HDR slope and anti-Xa heparin concentration, antithrombin and complete blood count. The target ACT of 450 s was not achieved in 68.6% of patients. Compared with patients who achieved the target ACT, those who failed to achieve their target ACT had a significantly higher platelet count at baseline. Correlation between the HDR slope and heparin sensitivity was poor. Projected heparin concentration and anti-Xa heparin concentration are not interchangeable based on the Bland-Altman analysis. It can be hypothesized that the wide discrepancy in HDR slope versus heparin sensitivity may be explained by an inaccurate prediction of the plasma heparin level and/or the change in HDR of individual patients, depending on in vivo factors such as extravascular sequestration of heparin, decreased intrinsic antithrombin activity level and platelet count and/or activity.

  4. Analysis of the Clean Air Act Amendments of 1990: A forecast of the electric utility industry response to Title IV, Acid Deposition Control

    Molburg, J.C.; Fox, J.A.; Pandola, G.; Cilek, C.M.

    1991-10-01

    The Clean Air Act Amendments of 1990 incorporate, for the first time, provisions aimed specifically at the control of acid rain. These provisions restrict emissions of sulfur dioxide (SO 2 ) and oxides of nitrogen (NO x ) from electric power generating stations. The restrictions on SO 2 take the form of an overall cap on the aggregate emissions from major generating plants, allowing substantial flexibility in the industry's response to those restrictions. This report discusses one response scenario through the year 2030 that was examined through a simulation of the utility industry based on assumptions consistent with characterizations used in the National Energy Strategy reference case. It also makes projections of emissions that would result from the use of existing and new capacity and of the associated additional costs of meeting demand subject to the emission limitations imposed by the Clean Air Act. Fuel-use effects, including coal-market shifts, consistent with the response scenario are also described. These results, while dependent on specific assumptions for this scenario, provide insight into the general character of the likely utility industry response to Title IV

  5. Analysis of the Clean Air Act Amendments of 1990: A forecast of the electric utility industry response to Title IV, Acid Deposition Control

    Molburg, J.C.; Fox, J.A.; Pandola, G.; Cilek, C.M.

    1991-10-01

    The Clean Air Act Amendments of 1990 incorporate, for the first time, provisions aimed specifically at the control of acid rain. These provisions restrict emissions of sulfur dioxide (SO{sub 2}) and oxides of nitrogen (NO{sub x}) from electric power generating stations. The restrictions on SO{sub 2} take the form of an overall cap on the aggregate emissions from major generating plants, allowing substantial flexibility in the industry`s response to those restrictions. This report discusses one response scenario through the year 2030 that was examined through a simulation of the utility industry based on assumptions consistent with characterizations used in the National Energy Strategy reference case. It also makes projections of emissions that would result from the use of existing and new capacity and of the associated additional costs of meeting demand subject to the emission limitations imposed by the Clean Air Act. Fuel-use effects, including coal-market shifts, consistent with the response scenario are also described. These results, while dependent on specific assumptions for this scenario, provide insight into the general character of the likely utility industry response to Title IV.

  6. Analysis of the Clean Air Act Amendments of 1990: A forecast of the electric utility industry response to Title IV, Acid Deposition Control

    Molburg, J.C.; Fox, J.A.; Pandola, G.; Cilek, C.M.

    1991-10-01

    The Clean Air Act Amendments of 1990 incorporate, for the first time, provisions aimed specifically at the control of acid rain. These provisions restrict emissions of sulfur dioxide (SO[sub 2]) and oxides of nitrogen (NO[sub x]) from electric power generating stations. The restrictions on SO[sub 2] take the form of an overall cap on the aggregate emissions from major generating plants, allowing substantial flexibility in the industry's response to those restrictions. This report discusses one response scenario through the year 2030 that was examined through a simulation of the utility industry based on assumptions consistent with characterizations used in the National Energy Strategy reference case. It also makes projections of emissions that would result from the use of existing and new capacity and of the associated additional costs of meeting demand subject to the emission limitations imposed by the Clean Air Act. Fuel-use effects, including coal-market shifts, consistent with the response scenario are also described. These results, while dependent on specific assumptions for this scenario, provide insight into the general character of the likely utility industry response to Title IV.

  7. Privacy Act

    Learn about the Privacy Act of 1974, the Electronic Government Act of 2002, the Federal Information Security Management Act, and other information about the Environmental Protection Agency maintains its records.

  8. Germline polymorphisms may act as predictors of response to preoperative chemoradiation in locally advanced T3 rectal tumors

    Spindler, Karen-Lise G; Nielsen, Jens N; Lindebjerg, Jan

    2007-01-01

    ) followed by total mesorectal excision eight weeks after treatment. Pathologic response was evaluated according to the tumor regression grade system. RESULTS: Thirty percent (18/60) of patients presented with complete pathologic response. Patients with thymidylate synthase genotype 2/2 had a significantly...

  9. Association of blood eosinophils and plasma periostin with FEV1 response after 3-month inhaled corticosteroid and long-acting beta2-agonist treatment in stable COPD patients.

    Park, Hye Yun; Lee, Hyun; Koh, Won-Jung; Kim, Seonwoo; Jeong, Ina; Koo, Hyeon-Kyoung; Kim, Tae-Hyung; Kim, Jin Woo; Kim, Woo Jin; Oh, Yeon-Mok; Sin, Don D; Lim, Seong Yong; Lee, Sang-Do

    2016-01-01

    COPD patients with increased airway eosinophilic inflammation show a favorable response to inhaled corticosteroids (ICS) in combination with a long-acting bronchodilator. Recent studies have demonstrated a significant correlation of sputum eosinophilia with blood eosinophils and periostin. We investigated whether high blood eosinophils and plasma periostin were associated with an improvement in forced expiratory volume in 1 second (FEV1) after 3-month treatment with ICS/long-acting beta2-agonist (LABA) in stable COPD patients. Blood eosinophils and plasma periostin levels were measured in 130 stable COPD subjects selected from the Korean Obstructive Lung Disease cohort. Subjects began a 3-month ICS/LABA treatment after washout period. High blood eosinophils (>260/µL, adjusted odds ratio =3.52, P=0.009) and high plasma periostin (>23 ng/mL, adjusted odds ratio =3.52, P=0.013) were significantly associated with FEV1 responders (>12% and 200 mL increase in FEV1 from baseline after treatment). Moreover, the addition of high blood eosinophils to age, baseline positive bronchodilator response, and FEV1 eosinophils and high plasma periostin were associated with improved lung function after 3-month ICS/LABA treatment. In particular, high blood eosinophils, in combination with age and baseline lung function parameters, might be a possible biomarker for identification of COPD patients with favorable FEV1 improvement in response to ICS/LABA treatment.

  10. The German act on the reorganisation of responsibility in nuclear waste management; Des Gesetz zur Neuordnung der Verantwortung in der kerntechnischen Entsorgung

    Raetzke, Christian [CONLAR Consulting on Nuclear Law and Regulation, Leipzig (Germany)

    2017-04-15

    The author discussed the Draft on the Act in the Reorganisation of Responsibility in Nuclear Waste Management in atw 12 (2016). Now, amendments are discussed, which resulted from the legislative procedure until today's draft. Significant additions affect the authorisation for the conclusion of a public-law contract between the Federal Government and the nuclear power plant operators, the deadline for the payment of the basic amount, and the option for the operation of the interim storage facilities for a transitional period by the operators on behalf of the federal company. Since the adoption of the draft act, it has become clear that the nuclear power plant operators will pay the risk premium. This will fulfil the full logic of the new system. It has also become known, that the public law contract is now ready for signing. According to the author, the act will bring a final arrangement for financing nuclear waste disposal. However, adjustment can not be avoided in practice. The concrete implementation will be a exciting topic in many ways.

  11. Cis-acting mutation and duplication: History of molecular evolution in a P450 haplotype responsible for insecticide resistance in Culex quinquefasciatus.

    Itokawa, Kentaro; Komagata, Osamu; Kasai, Shinji; Masada, Masahiro; Tomita, Takashi

    2011-07-01

    A cytochrome P450 gene, Cyp9m10, is more than 200-fold overexpressed in a pyrethroid resistant strain of Culex quinquefasciatus, JPal-per. The haplotype of this strain contains two copies of Cyp9m10 resulted from recent tandem duplication. In this study, we discovered and isolated a Cyp9m10 haplotype closely related to this duplicated Cyp9m10 haplotype from JHB, a strain used for the recent genome project for this mosquito species. The isolated haplotype (JHB-NIID-B haplotype) shared the same insertion of a transposable element upstream of the coding region with JPal-per strain but not duplicated. The JHB-NIID-B haplotype was considered to have diverged from the JPal-per lineage just before the duplication event. Cyp9m10 was moderately overexpressed in larvae with the JHB-NIID-B haplotype. The overexpressions in JHB-NIID-B and JPal-per haplotypes were developmentally regulated in similar pattern indicating both haplotypes share a common cis-acting mutation responsible for the overexpressions. The isolated moderately overexpressed haplotype conferred resistance, however, its efficacy was relatively small. We hypothesized that the first cis-acting mutation modified the consequence of the subsequent duplication in JPal-per lineage to confer stronger phenotypic effect than that if it occurred before the first cis-acting mutation. Copyright © 2011 Elsevier Ltd. All rights reserved.

  12. Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) or Superfund, Section 104(k); and CERCLA Section 104(d); ‘‘ ‘Discounted Loans’ Under Brownfields Revolving Loan Fund Grants’

    Comprehensive Environmental Response, Compensation and Liability Act (CERCLA) or Superfund, Section 104(k); and CERCLA Section 104(d); ‘‘ ‘Discounted Loans’ Under Brownfields Revolving Loan Fund Grants’`

  13. 78 FR 27211 - Privacy Act of 1974; System of Records-Evaluation of Response to Intervention Practices for...

    2013-05-09

    ... questions that the study will address are: (1) What is the average impact on academic achievement of... as at risk for reading difficulties compared with children just above the cutoff point for providing..., vary with elementary schools' adoption of Response to Intervention practices for early grade reading...

  14. Fiscal year 1995 progress in implementing Section 120 of the Comprehensive Environmental Response, Compensation, and Liability Act. Ninth annual report to Congress

    1996-09-01

    Congress passed the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) (Public Law 96-510), commonly known as Superfund, in 1980. The Superfund Amendments and Reauthorization Act (SARA) which amended CERCLA in 1986, added Section 120 regarding the cleanup of contaminated sites at Federal facilities. Under Section 120(e)(5) of CERCLA, each department, agency, or instrumentality of the Federal government responsible for compliance with Section 120 must submit an annual report to Congress concerning its progress in implementing the requirements of Section 120. The report must include information on the progress in reaching Interagency Agreements (IAGs), conducting Remedial Investigation and Feasibility Studies (RI/FSs), and performing remedial action. Federal agencies that own or operate facilities on the National priorities List (NPL) are required to begin an RI/FS for these facilities within 6 months after being placed on the NPL. Remediation of these facilities is addressed in an IAG between the Federal agency, the US Environmental Protection Agency (EPA), and in some instances the state within which the facility is located. This report provides the status of ongoing activities being performed in support of CERCLA Section 120 at DOE facilities. This includes activities conducted to reach IAGs and progress in conducting remedial actions

  15. Fiscal year 1995 progress in implementing Section 120 of the Comprehensive Environmental Response, Compensation, and Liability Act. Ninth annual report to Congress

    NONE

    1996-09-01

    Congress passed the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) (Public Law 96-510), commonly known as Superfund, in 1980. The Superfund Amendments and Reauthorization Act (SARA) which amended CERCLA in 1986, added Section 120 regarding the cleanup of contaminated sites at Federal facilities. Under Section 120(e)(5) of CERCLA, each department, agency, or instrumentality of the Federal government responsible for compliance with Section 120 must submit an annual report to Congress concerning its progress in implementing the requirements of Section 120. The report must include information on the progress in reaching Interagency Agreements (IAGs), conducting Remedial Investigation and Feasibility Studies (RI/FSs), and performing remedial action. Federal agencies that own or operate facilities on the National priorities List (NPL) are required to begin an RI/FS for these facilities within 6 months after being placed on the NPL. Remediation of these facilities is addressed in an IAG between the Federal agency, the US Environmental Protection Agency (EPA), and in some instances the state within which the facility is located. This report provides the status of ongoing activities being performed in support of CERCLA Section 120 at DOE facilities. This includes activities conducted to reach IAGs and progress in conducting remedial actions.

  16. Fiscal year 1996 progress in implementing Section 120 of the Comprehensive Environmental Response, Compensation, and Liability Act. Tenth annual report to Congress

    NONE

    1997-12-01

    Congress passed the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) (Public Law 96-510), commonly known as Superfund, in 1980. The Superfund Amendments and Reauthorization Act (SARA) (Public Law 99-499), which amended CERCLA in 1986, added Section 120 regarding the cleanup of contaminated sites at Federal facilities. Under Section 120(e)(5) of CERCLA, each department, agency, or instrumentality of the Federal government responsible for compliance with Section 120 must submit an annual report to Congress concerning its progress in implementing the requirements of Section 120. The report must include information on the progress in reaching Interagency Agreements (IAGs), conducting remedial investigation and feasibility studies (RI/FSs), and performing remedial actions. Federal agencies that own or operate facilities on the National Priorities List (NPL) are required to begin an RI/FS for these facilities within 6 months after being placed on the NPL. Remediation of these facilities is addressed in an IAG between the Federal agency, the US Environmental Protection Agency (EPA), and in some instances the state within which the facility is located.

  17. ACTS – SUCCESS STORY

    First page Back Continue Last page Overview Graphics. ACTS – SUCCESS STORY. Totally 103 experiments were conducted and the programme succeeded in the areas. Medicine; Education; Defence; Emergency Response; Maritime and Aeronautical Mobile Communications; Science and Astronomy.

  18. IB-12LUNG MASS AND IMMUNOSUPPRESSANT RESPONSIVE SEIZURES: VGKC AUTOIMMUNITY MASQUERADING AS ETIOLOGY OR ACTING AS REACTIVE MARKER?

    Umemura, Yoshie; Bujarski, Krzysztof; Ronan, Lara

    2014-01-01

    Voltage gated potassium channel complex antibody (VGKC Ab) has been associated with many neurological illnesses including seizures. VGKC Ab related seizures are less responsive to antiepileptic drugs alone, and often require immunosuppression to achieve seizure freedom. Recently, specific antigenic targets such as LGI1 and CASPR2 within VGKC have been found and have been associated with specific syndromes. It has also been noted that the term "VGKC Ab" itself is problematic because it groups ...

  19. Green propolis phenolic compounds act as vaccine adjuvants, improving humoral and cellular responses in mice inoculated with inactivated vaccines

    Geferson Fischer

    2010-11-01

    Full Text Available Adjuvants play an important role in vaccine formulations by increasing their immunogenicity. In this study, the phenolic compound-rich J fraction (JFR of a Brazilian green propolis methanolic extract stimulated cellular and humoral immune responses when co-administered with an inactivated vaccine against swine herpesvirus type 1 (SuHV-1. When compared to control vaccines that used aluminium hydroxide as an adjuvant, the use of 10 mg/dose of JFR significantly increased (p < 0.05 neutralizing antibody titres against SuHV-1, as well as the percentage of protected animals following SuHV-1 challenge (p < 0.01. Furthermore, addition of phenolic compounds potentiated the performance of the control vaccine, leading to increased cellular and humoral immune responses and enhanced protection of animals after SuHV-1 challenge (p < 0.05. Prenylated compounds such as Artepillin C that are found in large quantities in JFR are likely to be the substances that are responsible for the adjuvant activity.

  20. Radiological Protection Act 1970

    1970-01-01

    This Act provides for the establishment of a Radiological Protection Board to undertake research and advise on protection from radiation hazards. Its functions include provision of advice to Government departments with responsibilities in relation to protection of sectors of the community or the community as a whole against the hazards of ionizing radiation. The Act, which lays down that the Board shall replace certain departments concerned with radiation protection, repeals several Sections of the Radioactive Substances Act 1948 and the Science and Technology Act 1965. (NEA) [fr

  1. Gene-based association identifies SPATA13-AS1 as a pharmacogenomic predictor of inhaled short-acting beta-agonist response in multiple population groups.

    Padhukasahasram, B; Yang, J J; Levin, A M; Yang, M; Burchard, E G; Kumar, R; Kwok, P-Y; Seibold, M A; Lanfear, D E; Williams, L K

    2014-08-01

    Inhaled short-acting beta-agonist (SABA) medication is commonly used in asthma patients to rapidly reverse airway obstruction and improve acute symptoms. We performed a genome-wide association study of SABA medication response using gene-based association tests. A linear mixed model approach was first used for single-nucleotide polymorphism associations, and the results were later combined using GATES to generate gene-based associations. Our results identified SPATA13-AS1 as being significantly associated with SABA bronchodilator response in 328 healthy African Americans. In replication, this gene was associated with SABA response among the two separate groups of African Americans with asthma (n=1073, P=0.011 and n=1968, P=0.014), 149 healthy African Americans (P=0.003) and 556 European Americans with asthma (P=0.041). SPATA13-AS1 was also associated with longitudinal SABA medication usage in the two separate groups of African Americans with asthma (n=658, P=0.047 and n=1968, P=0.025). Future studies are needed to delineate the precise mechanism by which SPATA13-AS1 may influence SABA response.

  2. Identification and molecular characterization of a trans-acting small interfering RNA producing locus regulating leaf rust responsive gene expression in wheat (Triticum aestivum L.).

    Dutta, Summi; Kumar, Dhananjay; Jha, Shailendra; Prabhu, Kumble Vinod; Kumar, Manish; Mukhopadhyay, Kunal

    2017-11-01

    A novel leaf rust responsive ta-siRNA-producing locus was identified in wheat showing similarity to 28S rRNA and generated four differentially expressing ta-siRNAs by phasing which targeted stress responsive genes. Trans-acting-small interfering RNAs (Ta-siRNAs) are plant specific molecules generally involved in development and are also stress responsive. Ta-siRNAs identified in wheat till date are all responsive to abiotic stress only. Wheat cultivation is severely affected by rusts and leaf rust particularly affects grain filling. This study reports a novel ta-siRNA producing locus (TAS) in wheat which is a segment of 28S ribosomal RNA but shows differential expression during leaf rust infestation. Four small RNA libraries prepared from wheat Near Isogenic Lines were treated with leaf rust pathogen and compared with untreated controls. A TAS with the ability to generate four ta-siRNAs by phasing events was identified along with the microRNA TamiR16 as the phase initiator. The targets of the ta-siRNAs included α-gliadin, leucine rich repeat, trans-membrane proteins, glutathione-S-transferase, and fatty acid desaturase among others, which are either stress responsive genes or are essential for normal growth and development of plants. Expression of the TAS, its generated ta-siRNAs, and their target genes were profiled at five different time points after pathogen inoculation of susceptible and resistant wheat isolines and compared with mock-inoculated controls. Comparative analysis of expression unveiled differential and reciprocal relationship as well as discrete patterns between susceptible and resistant isolines. The expression profiles of the target genes of the identified ta-siRNAs advocate more towards effector triggered susceptibility favouring pathogenesis. The study helps in discerning the functions of wheat genes regulated by ta-siRNAs in response to leaf rust.

  3. IB-12LUNG MASS AND IMMUNOSUPPRESSANT RESPONSIVE SEIZURES: VGKC AUTOIMMUNITY MASQUERADING AS ETIOLOGY OR ACTING AS REACTIVE MARKER?

    Umemura, Yoshie; Bujarski, Krzysztof; Ronan, Lara

    2014-01-01

    Voltage gated potassium channel complex antibody (VGKC Ab) has been associated with many neurological illnesses including seizures. VGKC Ab related seizures are less responsive to antiepileptic drugs alone, and often require immunosuppression to achieve seizure freedom. Recently, specific antigenic targets such as LGI1 and CASPR2 within VGKC have been found and have been associated with specific syndromes. It has also been noted that the term "VGKC Ab" itself is problematic because it groups LGI1 and CASPR2 mediated disorders with other illnesses with unknown antigenic specificity. We describe a case of faciobrachial dystonia seizures refractory to multiple antiepileptic agents. Video EEG monitoring revealed mesial frontal epileptic discharges and serum test was positive for VGKC Ab. Patient's seizures were controlled after intravenous corticosteroid then oral mycophenolate maintenance, however, seizures returned with immunotherapy taper and cessation. When the seizures recurred, serum VGKC Ab, CSF CASPR 2 and LGI1 Abs were negative. Interestingly, she was subsequently found to have a lung mass consistent with sarcoidosis. Seizure control was achieved again with restarting of mycophenolate. Most VGKC Ab related illnesses are autoimmune even though it is a part of readily available commercial paraneoplastic testing panels. There has been no previously reported VGKC Ab related seizures associated with sarcoidosis. Although sarcoidosis is also an autoimmune entity, it is of T-cell mediated condition. It has been proposed that VGKC Ab may be a part of normal autoantibodies found in otherwise healthy individuals, which can rise to detectable levels under some circumstances. This patient suffered recurrent seizures responsive to immunotherapy even though VGKC, LGI1, and CASPR2 Abs were negative, suggesting another underlying autoimmune pathogenesis and VGKC Ab may have been a mere reactive marker of such underlying process. This raises the question of clinical

  4. ACTS 2014

    Co-curator of ACTS 2014 together with Rasmus Holmboe, Judith Schwarzbart and Sanne Kofoed. ACTS is the Museum of Contemporary Art’s international bi-annual festival. ACTS was established in 2011 and, while the primary focus is on sound and performance art, it also looks toward socially oriented art....... For the 2014 festival, the museum has entered into a collaboration with the Department for Performance Design at Roskilde University – with continued focus on sound and performance art, and social art in public spaces. With ACTS, art moves out of its usual exhibition space and instead utilizes the city, its...... various possibilities and public spaces as a stage. ACTS takes place in and around the museum and diverse locations in Roskilde city. ACTS is partly curated by the museum staff and partly by guest curators. ACTS 2014 is supported by Nordea-fonden and is a part of the project The Museum goes downtown....

  5. Hazard Ranking System evaluation of CERCLA [Comprehensive Environmental Response, Compensation, and Liability Act] inactive waste sites at Hanford: Volume 1, Evaluation methods and results

    Stenner, R.D.; Cramer, K.H.; Higley, K.A.; Jette, S.J.; Lamar, D.A.; McLaughlin, T.J.; Sherwood, D.R.; Van Houten, N.C.

    1988-10-01

    The purpose of this report is to formally document the individual site Hazard Ranking System (HRS) evaluations conducted as part of the preliminary assessment/site inspection (PA/SI) activities at the US Department of Energy (DOE) Hanford Site. These activities were carried out pursuant to the DOE orders that describe the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Program addressing the cleanup of inactive waste sites. These orders incorporate the US Environmental Protection Agency methodology, which is based on the Superfund Amendments and Reauthorization Act of 1986 (SARA). The methodology includes six parts: PA/SI, remedial investigation/feasibility study, record of decision, design and implementation of remedial action, operation and monitoring, and verification monitoring. Volume 1 of this report discusses the CERCLA inactive waste-site evaluation process, assumptions, and results of the HRS methodology employed. Volume 2 presents the data on the individual CERCLA engineered-facility sites at Hanford, as contained in the Hanford Inactive Site Surveillance (HISS) Data Base. Volume 3 presents the data on the individual CERCLA unplanned-release sites at Hanford, as contained in the HISS Data Base. 34 refs., 43 figs., 47 tabs

  6. Hazard Ranking System evaluation of CERCLA (Comprehensive Environmental Response, Compensation, and Liability Act) inactive waste sites at Hanford: Volume 1, Evaluation methods and results

    Stenner, R.D.; Cramer, K.H.; Higley, K.A.; Jette, S.J.; Lamar, D.A.; McLaughlin, T.J.; Sherwood, D.R.; Van Houten, N.C.

    1988-10-01

    The purpose of this report is to formally document the individual site Hazard Ranking System (HRS) evaluations conducted as part of the preliminary assessment/site inspection (PA/SI) activities at the US Department of Energy (DOE) Hanford Site. These activities were carried out pursuant to the DOE orders that describe the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Program addressing the cleanup of inactive waste sites. These orders incorporate the US Environmental Protection Agency methodology, which is based on the Superfund Amendments and Reauthorization Act of 1986 (SARA). The methodology includes six parts: PA/SI, remedial investigation/feasibility study, record of decision, design and implementation of remedial action, operation and monitoring, and verification monitoring. Volume 1 of this report discusses the CERCLA inactive waste-site evaluation process, assumptions, and results of the HRS methodology employed. Volume 2 presents the data on the individual CERCLA engineered-facility sites at Hanford, as contained in the Hanford Inactive Site Surveillance (HISS) Data Base. Volume 3 presents the data on the individual CERCLA unplanned-release sites at Hanford, as contained in the HISS Data Base. 34 refs., 43 figs., 47 tabs.

  7. Association of MicroRNA-196a2 Variant with Response to Short-Acting β2-Agonist in COPD: An Egyptian Pilot Study

    Fawzy, Manal S.; Hussein, Mohammad H.; Abdelaziz, Eman Z.; Yamany, Hussain A.; Ismail, Hussein M.; Toraih, Eman A.

    2016-01-01

    Chronic obstructive pulmonary disease (COPD) is a multifactorial chronic respiratory disease, characterized by an obstructive pattern. Understanding the genetic predisposition of COPD is essential to develop personalized treatment regimens. MicroRNAs (miRNAs) are small, endogenous, non-coding RNAs that modulate the expression levels of specific proteins based on sequence complementarity with their target mRNA molecules. Emerging evidences demonstrated the potential use of miRNAs as a disease biomarker. This pilot study aimed to investigate the association of the MIR-196a2 rs11614913 (C/T) polymorphism with COPD susceptibility, the clinical outcome and bronchodilator response to short-acting β2-agonist. Genotyping of rs11614913 polymorphism was determined in 108 COPD male patients and 116 unrelated controls using real-time polymerase chain reaction technology. In silico target prediction and network core analysis were performed. COPD patients did not show significant differences in the genotype distribution (p = 0.415) and allele frequencies (p = 0.306) of the studied miRNA when compared with controls. There were also no associations with GOLD stage, dyspnea grade, disease exacerbations, COPD assessment test for estimating impact on health status score, or the frequency of intensive care unit admission. However, COPD patients with CC genotype corresponded to the smallest bronchodilator response after Salbutamol inhalation, the heterozygotes (CT) had an intermediate response, while those with the TT genotype showed the highest response (p < 0.001). In conclusion MIR-196a2 rs11614913 polymorphism is associated with the bronchodilator response of COPD in our sample of the Egyptian population, generating hypothesis of the potential use of MIR-196a2 variant as a pharmacogenetic marker for COPD. PMID:27043015

  8. ENVIRONMENTAL REVIEWS AND CASE STUDIES: Addressing the Public Outreach Responsibilities of the National Historic Preservation Act: Argonne National Laboratory’s Box Digital Display Platform

    O’Rourke, Daniel J.; Weber, Cory C.; Richmond, Pamela D.

    2016-07-29

    Federal agencies are made responsible for managing the historic properties under their jurisdiction by the National Historic Preservation Act of 1966, as amended. A component of this responsibility is to mitigate the effect of a federal undertaking on historic properties through mitigation often through documentation. Providing public access to this documentation has always been a challenge. To address the issue of public access to mitigation information, personnel from Argonne National Laboratory created the Box Digital Display Platform, a system for communicating information about historic properties to the public. The platform, developed for the US Army Dugway Proving Ground, uses short introductory videos to present a topic but can also incorporate photos, drawings, GIS information, and documents. The system operates from a small, self-contained computer that can be attached to any digital monitor via an HDMI cable. The system relies on web-based software that allows the information to be republished as a touch-screen device application or as a website. The system does not connect to the Internet, and this increases security and eliminates the software maintenance fees associated with websites. The platform is designed to incorporate the products of past documentation to make this information more accessible to the public; specifically those documentations developed using the Historic American Building Survey/ Historic American Engineering Record (HABS/HAER) standards. Argonne National Laboratory’s Box Digital Display Platform can assist federal agencies in complying with the requirements of the National Historic Preservation Act.

    Environmental Practice 18: 209–213 (2016)

  9. Genes that act downstream of sensory neurons to influence longevity, dauer formation, and pathogen responses in Caenorhabditis elegans.

    Marta M Gaglia

    Full Text Available The sensory systems of multicellular organisms are designed to provide information about the environment and thus elicit appropriate changes in physiology and behavior. In the nematode Caenorhabditis elegans, sensory neurons affect the decision to arrest during development in a diapause state, the dauer larva, and modulate the lifespan of the animals in adulthood. However, the mechanisms underlying these effects are incompletely understood. Using whole-genome microarray analysis, we identified transcripts whose levels are altered by mutations in the intraflagellar transport protein daf-10, which result in impaired development and function of many sensory neurons in C. elegans. In agreement with existing genetic data, the expression of genes regulated by the transcription factor DAF-16/FOXO was affected by daf-10 mutations. In addition, we found altered expression of transcriptional targets of the DAF-12/nuclear hormone receptor in the daf-10 mutants and showed that this pathway influences specifically the dauer formation phenotype of these animals. Unexpectedly, pathogen-responsive genes were repressed in daf-10 mutant animals, and these sensory mutants exhibited altered susceptibility to and behavioral avoidance of bacterial pathogens. Moreover, we found that a solute transporter gene mct-1/2, which was induced by daf-10 mutations, was necessary and sufficient for longevity. Thus, sensory input seems to influence an extensive transcriptional network that modulates basic biological processes in C. elegans. This situation is reminiscent of the complex regulation of physiology by the mammalian hypothalamus, which also receives innervations from sensory systems, most notably the visual and olfactory systems.

  10. DNA Polymerase α (swi7) and the Flap Endonuclease Fen1 (rad2) Act Together in the S-Phase Alkylation Damage Response in S. pombe

    Koulintchenko, Milana; Vengrova, Sonya; Eydmann, Trevor; Arumugam, Prakash; Dalgaard, Jacob Z.

    2012-01-01

    Polymerase α is an essential enzyme mainly mediating Okazaki fragment synthesis during lagging strand replication. A specific point mutation in Schizosaccharomyces pombe polymerase α named swi7-1, abolishes imprinting required for mating-type switching. Here we investigate whether this mutation confers any genome-wide defects. We show that the swi7-1 mutation renders cells hypersensitive to the DNA damaging agents methyl methansulfonate (MMS), hydroxyurea (HU) and UV and incapacitates activation of the intra-S checkpoint in response to DNA damage. In addition we show that, in the swi7-1 background, cells are characterized by an elevated level of repair foci and recombination, indicative of increased genetic instability. Furthermore, we detect novel Swi1-, -Swi3- and Pol α- dependent alkylation damage repair intermediates with mobility on 2D-gel that suggests presence of single-stranded regions. Genetic interaction studies showed that the flap endonuclease Fen1 works in the same pathway as Pol α in terms of alkylation damage response. Fen1 was also required for formation of alkylation- damage specific repair intermediates. We propose a model to explain how Pol α, Swi1, Swi3 and Fen1 might act together to detect and repair alkylation damage during S-phase. PMID:23071723

  11. AguR, a Transmembrane Transcription Activator of the Putrescine Biosynthesis Operon in Lactococcus lactis, Acts in Response to the Agmatine Concentration.

    Linares, Daniel M; Del Rio, Beatriz; Redruello, Begoña; Ladero, Victor; Martin, M Cruz; de Jong, Anne; Kuipers, Oscar P; Fernandez, Maria; Alvarez, Miguel A

    2015-09-01

    Dairy industry fermentative processes mostly use Lactococcus lactis as a starter. However, some dairy L. lactis strains produce putrescine, a biogenic amine that raises food safety and spoilage concerns, via the agmatine deiminase (AGDI) pathway. The enzymatic activities responsible for putrescine biosynthesis in this bacterium are encoded by the AGDI gene cluster. The role of the catabolic genes aguB, aguD, aguA, and aguC has been studied, but knowledge regarding the role of aguR (the first gene in the cluster) remains limited. In the present work, aguR was found to be a very low level constitutively expressed gene that is essential for putrescine biosynthesis and is transcribed independently of the polycistronic mRNA encoding the catabolic genes (aguBDAC). In response to agmatine, AguR acts as a transcriptional activator of the aguB promoter (PaguB), which drives the transcription of the aguBDAC operon. Inverted sequences required for PaguB activity were identified by deletion analysis. Further work indicated that AguR is a transmembrane protein which might function as a one-component signal transduction system that senses the agmatine concentration of the medium and, accordingly, regulates the transcription of the aguBDAC operon through a C-terminal cytoplasmic DNA-binding domain typically found in LuxR-like proteins. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  12. Curatorial Acts

    Bal, M.

    2012-01-01

    In a self-critical inquiry into my own recent work of co-curating and the experience of seeing my video work being curated by others, this article examines acts of framing as performative acts that seek to transform visitors' preconceptions. This affective effect is pursued by means of immersion,

  13. An aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress the Th17 response in allergic rhinitis patients.

    Wei, Ping; Hu, Guo-Hua; Kang, Hou-Yong; Yao, Hong-Bing; Kou, Wei; Liu, Hong; Zhang, Cheng; Hong, Su-Ling

    2014-05-01

    A predominant Th17 population is a marker of allergic rhinitis (AR). The aryl hydrocarbon receptor (AhR) exhibits strong immunomodulation potential via regulation of the differentiation of T lymphocytes and dendritic cells (DCs) after activation by its ligand, such as 2-(1'H-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE). The aim of this study was to analyze the effect of AhR on Th17 differentiation by investigating the action of ITE on DCs and CD4(+) T cells from patients with AR. In all, 26 AR patients and 12 healthy controls were included in this study. The expression of interleukin (IL)-1β, IL-6, IL-10, and IL-17 in the culture supernatant and the presence of Th17 cells in CD4(+) T cells and DC-CD4(+) T-cell co-culture system were measured before and after treatment with ITE. We show that ITE significantly induced cell secretion of IL-10 and inhibited IL-1β and IL-6 production in DCs, and promoted IL-10 production and suppressed IL-17 expression in CD4(+) T cells in vitro. It also suppressed the expansion of Th17 cells in vitro. Our work demonstrates that ITE acts on DCs and CD4(+) T cells to inhibit the Th17 response that suppresses AR; the AhR-DC-Th17 axis may be an important pathway in the treatment of AR. ITE, a nontoxic AhR ligand, attenuated the Th17 response; thus, it appears to be a promising therapeutic candidate for suppressing the inflammatory responses associated with AR.

  14. The Radiation Protection Act

    Persson, L.

    1989-01-01

    The new Radiation Protection Act (1988:220) entered into force in Sweden on July 1st, 1988. This book presents the Act as well as certain regulations connected to it. As previously, the main responsibility for public radiation protection will rest with one central radiation protection authority. According to the 1988 Act, the general obligations with regard to radiation protection will place a greater responsibility than in the past on persons carrying out activities involving radiation. Under the act, it is possible to adjust the licensing and supervisory procedures to the level of danger of the radiation source and the need for adequate competence, etc. The Act recognises standardised approval procedures combined with technical regulations for areas where the risks are well known. The Act contains several rules providing for more effective supervision. The supervising authority may in particular decide on the necessary regulations and prohibitions for each individual case. The possibilities of using penal provisions have been extended and a rule on the mandatory execution of orders has been introduced. The Ordinance on Radiation Protection (1988:293) designates the National Institute of Radiation Protection (SSI) as the central authority referred to in the Radiation Protection Act. The book also gives a historic review of radiation protection laws in Sweden, lists regulations issued by SSI and presents explanations of radiation effects and international norms in the area. (author)

  15. ACT Test

    ... to clot, the higher the degree of clotting inhibition. During surgery, the ACT is kept above a ... What is ECLS? An Introduction to Extracorporeal Life Support. University of Michigan Health System [On-line information]. ...

  16. Shift in U.S. payer responsibility for the acute care of violent injuries after the Affordable Care Act: Implications for prevention.

    Coupet, Edouard; Karp, David; Wiebe, Douglas J; Kit Delgado, M

    2018-03-28

    Investment in violence prevention programs is hampered by lack of clearly identifiable stakeholders with a financial stake in prevention. We determined the total annual charges for the acute care of injuries from interpersonal violence and the shift in financial responsibility for these charges after the Medicaid expansion from the Affordable Care Act in 2014. We analyzed all emergency department (ED) visits from 2009 to 2014 with diagnosis codes for violent injury in the Nationwide Emergency Department Sample (NEDS). We used sample weights to estimate total charges with adjusted generalized linear models to estimate charges for the 15% of ED visits with missing charge data. We then calculated the share attributable by payer and determined the difference in proportion by payer from 2013 to 2014. Between 2009 and 2013, the uninsured accounted for 28.2-31.3% of annual charges for the acute care of violent injury, while Medicaid was responsible for a similar amount (29.0-31.0%). In 2014, there were $10.7 billion in total charges for violent injury. Medicaid assumed the greatest share, 39.8% (95% CI: 38.0-41.5%, $3.5-5.1 billion), while the uninsured accounted for 23.6% (95% CI: 22.2-24.9%, $2.0-3.0 billion), and Medicare accounted for 7.8% (95% CI: 7.7-8.0%, $0.7-1.0 billion). After Medicaid expansion, taxpayers are now accountable for nearly half of the $10.7 billion in annual charges for the acute care of violent injury in the U.S. These findings highlight the benefit to state Medicaid programs of preventing interpersonal violence. Published by Elsevier Inc.

  17. Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid Remifentanil in humans.

    Kosek, Eva; Jensen, Karin B; Lonsdorf, Tina B; Schalling, Martin; Ingvar, Martin

    2009-07-01

    There is evidence from animal studies that serotonin (5-HT) can influence the antinociceptive effects of opioids at the spinal cord level. Therefore, there could be an influence of genetic polymorphisms in the serotonin system on individual variability in response to opioid treatment of pain. The serotonin transporter (5-HTT) is a key regulator of serotonin metabolism and availability and its gene harbors several known polymorphisms that are known to affect 5-HTT expression (e.g. 5-HTTLPR, rs25531). The aim of this study was to investigate if the triallelic 5-HTTLPR influences pain sensitivity or the analgesic effect of opioids in humans. 43 healthy volunteers (12 men, 31 women, mean age 26 years) underwent heat pain stimulations before and after intravenous injection of Remifentanil; a rapid and potent opioid drug acting on micro-type receptors. Subjects rated their perceived pain on a visual analogue scale (VAS). All participants were genotyped for the 5-HTTLPR and the rs25531 polymorphism. We recruited by advertising, with no history of drug abuse, chronic pain or psychiatric disorders. At baseline, there was no difference in pain ratings for the different triallelic 5-HTTLPR genotype groups. However, the opiod drug had a differential analgesic effect depending on the triallelic 5-HTTLPR genotype. Remifentanil had a significantly better analgesic effect in individuals with a genotype coding for low 5-HTT expression (SA/SA and SA/LG) as compared to those with high expression(LA/LA), p desensitization of 5-HT1 receptors have an increased analgesic response to opioids during acute pain stimuli, but may still be at increased risk of developing chronic pain conditions.

  18. The response regulator expM is essential for the virulence of Erwinia carotovora subsp. carotovora and acts negatively on the sigma factor RpoS (sigma s).

    Andersson, R A; Palva, E T; Pirhonen, M

    1999-07-01

    The main virulence factors of Erwinia carotovora subsp. carotovora, the secreted, extracellular cell-wall-degrading enzymes, are controlled by several regulatory mechanisms. We have isolated transposon mutants with reduced virulence on tobacco. One of these mutants, with a mutation in a gene designated expM, was characterized in this study. This mutant produces slightly reduced amounts of extracellular enzymes in vitro and the secretion of the enzymes is also affected. The expM wild-type allele was cloned together with an upstream gene, designated expL, that has an unknown function. The expM gene was sequenced and found to encode a protein with similarity to the RssB/SprE protein of Escherichia coli and the MviA protein of Salmonella typhimurium. These proteins belong to a new type of two-component response regulators that negatively regulate the stability of the Sigma factor RpoS (sigma s) at the protein level. The results of this study suggest that ExpM has a similar function in E. carotovora subsp. carotovora. We also provide evidence that the overproduction of RpoS in the expM mutant is an important factor for the reduced virulence phenotype and that it partly causes the observed phenotype seen in vitro. However, an expM/rpoS double mutant is still affected in secretion of extracellular enzymes, suggesting that ExpM in addition to RpoS also acts on other targets.

  19. Therapeutic response of West African Dwarf goats infected with Peste des Petits Ruminants whose oral lesions were treated with oxytetracycline long acting and gentian violet topical spray

    Iniobong Chukwuebuka Ikenna Ugochukwu

    2017-11-01

    Full Text Available Objective: To assess the therapeutic response of West African Dwarf (WAD goats infected with Peste des Petits Ruminants (PPR virus treated with Amantidine hydrochloride. Methods: Apart from the presence of the characteristic clinical signs, complement ELISA and haemagglutination inhibition (HI tests were used to confirm PPR infection in the WAD goats. The oral lesions in one group were cleaned with 70% alcohol and treated with oxytetracycline long acting (LA intramuscularly (IM and topically treated with gentian violet spray which also contained oxytetracycline, and in another group WAD goats infected with PPR virus were only treated with oxytetracycline LA intramuscularly. Results: The oral lesions in the group cleaned with 70% alcohol, treated with oxyteteracycline LA intramuscularly and gentian violet spray which also contained oxytetracycline topically healed appreciably within 3 weeks before the termination of the experiment, while the group that was treated with oxyteteracycline LA intramuscularly only healed poorly. The mortality of the WAD goats with PPR whose oral lesions were not treated with gentian violet topical spray was 100%, while the mortality of WAD goats treated with oxytetracycline LA intramuscularly and gentian violet topical spray was 71.42%. Conclusions: The results of this present study suggest that in addition to antiviral therapy, cleaning with 70% alcohol, combination of oxytetracycline LA and topical spraying of the oral lesions with gentian violet spray which also contains oxytetracycline reduced the morbidity and mortality considerably.

  20. Predictors Associated with Increase in Skeletal Muscle Mass after Sustained Virological Response in Chronic Hepatitis C Treated with Direct Acting Antivirals

    Kazunori Yoh

    2017-10-01

    Full Text Available Aims: We aimed to examine changes in skeletal muscle mass in chronic hepatitis C (CHC patients undergoing interferon (IFN-free direct acting antivirals (DAAs therapy who achieved sustained virological response (SVR. Patients and methods: A total of 69 CHC patients treated with DAAs were analyzed. We compared the changes in skeletal muscle index (SMI using bio-impedance analysis at baseline and SMI at SVR. SMI was calculated as the sum of skeletal muscle mass in upper and lower extremities divided by height squared (cm2/m2. Further, we identified pretreatment parameters contributing to the increased SMI at SVR. Results: SMI in males at baseline ranged from 6.73 to 9.08 cm2/m2 (median, 7.65 cm2/m2, while that in females ranged from 4.45 to 7.27 cm2/m2 (median, 5.81 cm2/m2. At SVR, 36 patients (52.2% had increased SMI as compared with baseline. In the univariate analysis, age (p = 0.0392, hyaluronic acid (p = 0.0143, and branched-chain amino acid to tyrosine ratio (BTR (p = 0.0024 were significant pretreatment factors linked to increased SMI at SVR. In the multivariate analysis, only BTR was an independent predictor linked to the increased SMI at SVR (p = 0.0488. Conclusion: Pretreatment BTR level can be helpful for predicting increased SMI after SVR in CHC patients undergoing IFN-free DAAs therapy.

  1. Association of blood eosinophils and plasma periostin with FEV1 response after 3-month inhaled corticosteroid and long-acting beta2-agonist treatment in stable COPD patients

    Park HY

    2015-12-01

    Full Text Available Hye Yun Park,1 Hyun Lee,1 Won-Jung Koh,1 Seonwoo Kim,2 Ina Jeong,3 Hyeon-Kyoung Koo,4 Tae-Hyung Kim,5 Jin Woo Kim,6 Woo Jin Kim,7 Yeon-Mok Oh,8 Don D Sin,9 Seong Yong Lim,10,* Sang-Do Lee8,* On behalf of the KOLD Study Group 1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; 2Biostatistics Team, Samsung Biomedical Research Institute, Seoul, Korea; 3Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Medical Center, Seoul, Korea; 4Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea; 5Division of Pulmonary and Critical Care Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Gyeonggi-do, Korea; 6Division of Pulmonology, Department of Internal Medicine, Uijeongbu St Mary’s Hospital, Gyunggi-do, Korea; 7Department of Internal Medicine, Kangwon National University, Chuncheon-si, Gangwon-do, Korea; 8Department of Pulmonary and Critical Care Medicine, Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; 9Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, BC, Canada; 10Division of Pulmonary and Critical Care Medicine, Department of Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea *These authors contributed equally to this work Background: COPD patients with increased airway eosinophilic inflammation show a favorable response to inhaled corticosteroids (ICS in combination with a long-acting bronchodilator. Recent studies have demonstrated a significant correlation of sputum eosinophilia with blood eosinophils and periostin. We investigated whether high blood eosinophils and plasma periostin were associated

  2. How the Illegal Immigration Reform and Immigrant Responsibility Act of 1996 Has Undermined US Refugee Protection Obligations and Wasted Government Resources

    Eleanor Acer

    2017-05-01

    Full Text Available Seeking asylum is a human right, enshrined in the Universal Declaration of Human Rights. The 1951 Convention relating to the Status of Refugees (“Refugee Convention” and its 1967 Protocol relating to the Status of Refugees (“1967 Protocol” prohibit the United States from returning refugees to persecution, and the 1980 Refugee Act set up a formal process for applying for asylum in the United States. However, the Illegal Immigration Reform and Immigrant Responsibility Act of 1996 (IIRIRA created a barrage of new barriers to asylum. These impediments have blocked many refugees from accessing asylum in the United States and inserted additional layers of technicalities, screening, and processing, undermining the effectiveness of the US asylum system. The barriers imposed by IIRIRA are significant. They include a filing deadline on asylum applications, which prevents genuine refugees from receiving asylum if they cannot prove they have filed the application within one year of arriving in the United States. IIRIRA also established summary deportation procedures, including “expedited removal” and “reinstatement of removal,” which block asylum seekers from even applying for asylum or accessing an immigration court removal hearing, unless they first pass through a screening process. Finally, IIRIRA imposed “mandatory detention” on certain immigrants, including asylum seekers who are placed in expedited removal proceedings upon their arrival at a US port of entry. Each of these provisions imposed new processes and procedures that have contributed to an increasingly ineffective immigration system. The current backlog in the immigration courts has reached a record high, surpassing half a million cases, while the backlog of affirmative asylum cases before the Asylum Division of US Citizenship and Immigration Services (USCIS has increased by a factor of six [check] in just three years. Backlogs, which lead to long delays in adjudication

  3. Effect of β2-adrenergic receptor gene (ADRB2 3′ untranslated region polymorphisms on inhaled corticosteroid/long-acting β2-adrenergic agonist response

    Ambrose Helen J

    2012-05-01

    Full Text Available Abstract Background Evidence suggests that variation in the length of the poly-C repeat in the 3′ untranslated region (3′UTR of the β2-adrenergic receptor gene (ADRB2 may contribute to interindividual variation in β-agonist response. However, methodology in previous studies limited the assessment of the effect of sequence variation in the context of poly-C repeat length. The objectives of this study were to design a novel genotyping method to fully characterize sequence variation in the ADRB2 3′UTR poly-C repeat in asthma patients treated with inhaled corticosteroid and long-acting β2-adrenergic agonist (ICS/LABA combination therapy, and to analyze the effect of the poly-C repeat polymorphism on clinical response. Methods In 2,250 asthma patients randomized to treatment with budesonide/formoterol or fluticasone/salmeterol in a six-month study (AstraZeneca study code: SD-039-0735, sequence diversity in the ADRB2 poly-C repeat region was determined using a novel sequencing-based genotyping method. The relationship between the poly-C repeat polymorphism and the incidence of severe asthma exacerbations, and changes in pulmonary function and asthma symptoms from baseline to the average during the treatment period, were analyzed. Results Poly-C repeat genotypes were assigned in 97% (2,192/2,250 of patients. Of the 13 different poly-C repeat alleles identified, six alleles occurred at a frequency of >5% in one or more population in this study. The repeat length of these six common alleles ranged from 10 to 14 nucleotides. Twelve poly-C repeat genotypes were observed at a frequency of >1%. No evidence of an association between poly-C repeat genotype and the incidence of severe asthma exacerbations was observed. Patients’ pulmonary function measurements improved and asthma symptoms declined when treated with ICS/LABA combination therapy regardless of poly-C repeat genotype. Conclusions The extensive sequence diversity present in the poly

  4. Atomic Energy Control Act

    1970-01-01

    This act provides for the establishment of the Atomic Energy Control Board. The board is responsible for the control and supervision of the development, application and use of atomic energy. The board is also considered necessary to enable Canada to participate effectively in measures of international control of atomic energy

  5. Moderate Sustained Virologic Response Rates With 6-Week Combination Directly Acting Anti-Hepatitis C Virus Therapy in Patients With Advanced Liver Disease.

    Kattakuzhy, Sarah; Wilson, Eleanor; Sidharthan, Sreetha; Sims, Zayani; McLaughlin, Mary; Price, Angie; Silk, Rachel; Gross, Chloe; Akoth, Elizabeth; McManus, Maryellen; Emmanuel, Benjamin; Shrivastava, Shikha; Tang, Lydia; Nelson, Amy; Teferi, Gebeyehu; Chavez, Jose; Lam, Brian; Mo, Hongmei; Osinusi, Anuoluwapo; Polis, Michael A; Masur, Henry; Kohli, Anita; Kottilil, Shyamasundaran

    2016-02-15

    Treatment of genotype 1 hepatitis C virus (HCV) infection with combination directly acting antivirals (DAA) for 8-24 weeks is associated with high rates of sustained virologic response (SVR). We previously demonstrated that adding a third DAA to ledipasvir and sofosbuvir (LDV/SOF) can result in high SVR rates in patients without cirrhosis. In this study, we investigated whether a similar regimen would yield equivalent rates of cure in patients with advanced liver fibrosis. Fifty patients were enrolled at the Clinical Research Center of the National Institutes of Health and associated healthcare centers. Enrollment and follow-up data from April 2014 to June 2015 are reported here. Eligible participants were aged ≥18 years, had chronic HCV genotype 1 infection (serum HCV RNA ≥2000 IU/mL), and stage 3-4 liver fibrosis. HCV RNA was measured using a reverse-transcription polymerase chain reaction assay. Of patients treated with LDV, SOF, and the NS3/4A protease inhibitor GS-9451 for 6 weeks, 76% (38 of 50; 95% confidence interval, 60%-85%) had SVR achieved 12 weeks after the end of treatment. There was no statistically significant difference in treatment efficacy between treatment-naive patients (72%, 18 of 25) and those with treatment experience (80%; 20 of 25) (P = .51). Overall, 11 patients (22%) experienced virologic relapse, and 1 (2%) was lost to follow-up at 4 weeks after treatment. No serious adverse events, discontinuations, or deaths were associated with this regimen. Adding a third DAA to LDV/SOF may result in a moderate SVR rate, lower than that observed in patients without cirrhosis. Significant liver fibrosis remains an impediment to achieving SVR with short-duration DAA therapy. CT01805882. Published by Oxford University Press for the Infectious Diseases Society of America 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  6. Improvement of liver stiffness in patients with hepatitis C virus infection who received direct-acting antiviral therapy and achieved sustained virological response.

    Tada, Toshifumi; Kumada, Takashi; Toyoda, Hidenori; Mizuno, Kazuyuki; Sone, Yasuhiro; Kataoka, Saki; Hashinokuchi, Shinichi

    2017-12-01

    There is insufficient research on whether direct-acting antiviral (DAA) therapy can improve liver fibrosis in patients with chronic hepatitis C virus (HCV). We evaluated sequential changes in liver stiffness using shear wave elastography in patients with HCV who received DAA therapy. A total of 210 patients with HCV who received daclatasvir and asunaprevir therapy and achieved sustained virological response (SVR) were analyzed. Liver stiffness, as evaluated by shear wave elastography, and laboratory data were assessed before treatment (baseline), at end of treatment (EOT), and at 24 weeks after EOT (SVR24). Alanine aminotransferase levels (ALT) decreased over time, and there were significant differences between baseline and EOT and between EOT and SVR24. Although platelet counts did not significantly differ between baseline and EOT, they increased significantly from EOT to SVR24. The median (interquartile range) liver stiffness values at baseline, EOT, and SVR24 were 10.2 (7.7-14.7), 8.8 (7.1-12.1), and 7.6 (6.3-10.3) kPa, respectively (P liver) and Fibrosis-4 index > 2.0 (n = 75), the liver stiffness values at baseline, EOT, and SVR24 were 9.6 (7.7-15.2), 9.2 (7.3-12.1), and 7.7 (6.3-10.1) kPa, respectively (P liver stiffness starts during the administration of DAAs in patients who achieve SVR, and this effect is particularly pronounced in patients with progressive liver fibrosis. © 2017 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.

  7. Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531 influences the analgesic response to the short acting opioid Remifentanil in humans

    Schalling Martin

    2009-07-01

    Full Text Available Abstract Background There is evidence from animal studies that serotonin (5-HT can influence the antinociceptive effects of opioids at the spinal cord level. Therefore, there could be an influence of genetic polymorphisms in the serotonin system on individual variability in response to opioid treatment of pain. The serotonin transporter (5-HTT is a key regulator of serotonin metabolism and availability and its gene harbors several known polymorphisms that are known to affect 5-HTT expression (e.g. 5-HTTLPR, rs25531. The aim of this study was to investigate if the triallelic 5-HTTLPR influences pain sensitivity or the analgesic effect of opioids in humans. 43 healthy volunteers (12 men, 31 women, mean age 26 years underwent heat pain stimulations before and after intravenous injection of Remifentanil; a rapid and potent opioid drug acting on μ-type receptors. Subjects rated their perceived pain on a visual analogue scale (VAS. All participants were genotyped for the 5-HTTLPR and the rs25531 polymorphism. We recruited by advertising, with no history of drug abuse, chronic pain or psychiatric disorders. Results At baseline, there was no difference in pain ratings for the different triallelic 5-HTTLPR genotype groups. However, the opiod drug had a differential analgesic effect depending on the triallelic 5-HTTLPR genotype. Remifentanil had a significantly better analgesic effect in individuals with a genotype coding for low 5-HTT expression (SA/SA and SA/LG as compared to those with high expression(LA/LA, p Conclusion This is the first report showing an influence of the triallelic 5-HTTLPR on pain sensitivity or the analgesic effect of opioids in humans. Previously the 5-HTTLPR s-allele has been associated with higher risk of developing chronic pain conditions but in this study we show that the genotype coding for low 5-HTT expression is associated with a better analgesic effect of an opioid. The s-allele has been associated with downregulation of

  8. Expansion of plasmid mediated blaACT-2 among Pseudomonas aeruginosa associated with postoperative infection and its transcriptional response under cephalosporin stress.

    Birson Ingti, Deepjyoti Paul, Anand Prakash Maurya

    2017-06-01

    Full Text Available Objectives: Organisms harboring multiple plasmid mediated β-lactamases are major concerns in nosocomial infections. Among these plasmid mediated β-lactamases, ACT (EBC family is a clinically important enzyme capable of hydrolyzing broad spectrum cephalosporins. Therefore, the present study was undertaken to determine the prevalence of ACT determinant along with other co-existing β-lactamase genes in P. aeruginosa strains. Methods: A total of 176 Pseudomonas isolates were phenotypically screened for the presence of AmpC β-lactamase by M3DET Method followed by Molecular detection using PCR assay. Transcriptional evaluation of blaACT-2 gene was analyzed by RT-PCR and its transferability was performed by transformation and conjugation. Results: Present study demonstrates the presence of ACT-2 allele among 12 strains of P. aeruginosa. Co-existence of other β-lactamase genes were encountered among ACT-2 harboring strains which includes CTX-M (n=2, SHV (n=3, TEM (n=2, VEB (n=2, OXA-10 (n=1, CIT (n=2 and DHA (n=3. Fingerprinting by REP PCR revealed the isolates harboring ACT-2 to be distinct and these isolates showed high resistance to expanded-spectrum cephalosporins and even to carbapenem group of drugs. This ACT-2 allele was encoded in the plasmid (L/M, FIA, FIB Inc. Group and conjugatively transferable. Transcriptional analysis revealed a significant increase in ACT-2 expression (483 fold when induced by ceftriaxone at 4 µg/ml followed by ceftazidime at 8 µg/ml (31 fold and cefotaxime 4 µg/ml (8 fold. Conclusion: In this study detection of ACT-2 plasmid mediated AmpC β-lactamase along with other β-lactamase genes in clinical isolates of P. aeruginosa represents a serious therapeutic challenge. Therefore, revision in antimicrobial policy is required for effective treatment of patients infected with pathogen expressing this mechanism. J Microbiol Infect Dis 2017; 7(2: 75-82

  9. The Price-Anderson Act

    Jones, R.

    2000-01-01

    The Price-Anderson Act establishes nuclear liability law in the United States. First passed in 1957, it has influenced other nuclear liability legislation around the world. The insurer response the nuclear accident at Three Mile Island in 1979 demonstrates the application of the Act in a real life situation. The Price-Anderson Act is scheduled to be renewed in 2002, and the future use of commercial nuclear power in tge United States will be influenced by this renewal. (author)

  10. Online Challenge versus Offline ACT

    Peckham, Irvin

    2010-01-01

    This article compares essays written in response to the ACT Essay prompt and a locally developed prompt used for placement. The two writing situations differ by time and genre: the ACT Essay is timed and argumentative; the locally developed is untimed and explanatory. The article analyzes the differences in student performance and predictive…

  11. Atomic Energy Commission Act, 1963

    1963-01-01

    Promulgated in 1963, the Atomic Energy Commission Act (204) established and vested in the Ghana Atomic Energy Commission the sole responsibility for all matters relating to the peaceful uses of atomic energy in the country. Embodied in the Act are provisions relating to the powers, duties, rights and liabilities of the Commission. (EAA)

  12. Law no. 6.453 of 17th October, 1977 on civil liability for nuclear damage and criminal responsibility for acts relating to nuclear activities, and other provisions

    1977-01-01

    This Act was published on 17 october 1977. Under the Act the operator of a nuclear installation is exclusively liable regardless of fault for compensation of nuclear damage due to a nuclear incident. This exclusive liability is limited to an amount equal to 1,500,000 Treasury Bonds and the operator must take out the maintain insurance or other financial security to cover his liability. The Federative Government will guarantee, up to the prescribed limit, payment of compensation for nuclear damage where it is acknowledged that the operator's liability is involved. As regards apportionment of compensation, persons are granted priority over property. This Act is original in that it contains provisions on criminal liability with penalties ranging from two to ten years imprisonment

  13. Healing Arts Radiation Protection Act

    1984-07-01

    The Healing Arts Radiation Protection Act is concerned with regulating the registration, installation, operation, inspection and safety of X-ray machines. The Act provides for the establishment of the Healing Arts Radiation Protection Commission which is responsible for reporting on all the above matters to the Ontario Minister of Health. In addition the board is responsible for the continuing development of an X-ray safety code and for the submission of an annual report of their activities to the minister

  14. No 592 - Radiation Act

    1991-01-01

    This Act will enter into force on 1 January 1992. The scope of the Act is extensive as, in addition to ionizing radiation, it will also apply to activities involving exposure to natural radiation and non-ionizing radiation. Its purpose is to prevent and restrict harmful effects to health resulting from radiation. The basic principles of the Act are that the practice involving radiation should be justified; radiation protection should be optimized; and radiation doses should be as low as reasonably achievable. Licensed organisations using radiation will be responsible for the safety of the activity involving exposure to radiation and for having available the appropriate expertise to this effect. The required so-called safety licence provides the regulatory control to ensure that radiation is used sensibly, that the equipment and shields are technically acceptable and the operating personnel is competent, and that the radioactive waste is dealt with appropriately. The Radiation Act will also apply to nuclear activities within the scope of the 1987 Nuclear Energy Act [fr

  15. Plans and schedules for implementation of US Nuclear Regulatory Commission responsibilities under the Low-Level Radioactive Waste Policy Amendments Act of 1985 (P.L. 99-240)

    Dunkelman, M.M.

    1987-08-01

    This document makes available the plans and schedules for the US Nuclear Regulatory Commission's (NRC's) implementation of its responsibilities under the Low-Level Radioactive Waste Policy Amendments Act of 1985 (LLRWPAA). The present document identifies the provisions of the LLRWPAA that affect the programs of the NRC, identifies what the NRC must do to fulfill each of its requirements under the LLRWPAA, and establishes schedules for carrying out these requirements

  16. Response

    Higgins, Chris

    2012-01-01

    This article presents the author's response to the reviews of his book, "The Good Life of Teaching: An Ethics of Professional Practice." He begins by highlighting some of the main concerns of his book. He then offers a brief response, doing his best to address the main criticisms of his argument and noting where the four reviewers (Charlene…

  17. Interactions of trans-acting factor(s) with the estradiol response element and nuclear factor 1 of the vitellogenin II gene of Japanese quail.

    Gupta, S; Upadhayay, R; Kanungo, M S

    1996-08-01

    This study was directed at achieving an understanding of the mechanisms by which steroid hormones control the synthesis of vitellogenin (VTG) protein in the liver of the Japanese quail. Northern hybridization shows that administration of estradiol alone or with progesterone stimulates the synthesis of VTG mRNA. Gel mobility shift assay of DNA fragments containing the ERE and NF 1 shows that estradiol alone or with progesterone increases the levels of nuclear proteins that bind to these cis-acting elements of the promoter of the VTG gene. The cooperative effect of the two hormones seen at the level of expression of the VTG gene may be due to protein-protein interactions of trans-acting factors that bind to ERE and NF 1.

  18. Immigration and the War on Crime: Law and Order Politics and the Illegal Immigration Reform and Immigrant Responsibility Act of 1996

    Patrisia Macías-Rojas

    2018-01-01

    Full Text Available The 1996 Illegal Immigration Reform and Immigrant Responsibility Act (IIRIRA was a momentous law that recast undocumented immigration as a crime and fused immigration enforcement with crime control (García Hernández 2016; Lind 2016. Among its most controversial provisions, the law expanded the crimes, broadly defined, for which immigrants could be deported and legal permanent residency status revoked. The law instituted fast-track deportations and mandatory detention for immigrants with convictions. It restricted access to relief from deportation. It constrained the review of immigration court decisions and imposed barriers for filing class action lawsuits against the former US Immigration and Naturalization Service (INS. It provided for the development of biometric technologies to track “criminal aliens” and authorized the former INS to deputize state and local police and sheriff’s departments to enforce immigration law (Guttentag 1997a; Migration News 1997a, 1997b, 1997c; Taylor 1997. In short, it put into law many of the punitive provisions associated with the criminalization of migration today. Legal scholars have documented the critical role that IIRIRA played in fundamentally transforming immigration enforcement, laying the groundwork for an emerging field of “crimmigration” (Morris 1997; Morawetz 1998, 2000; Kanstroom 2000; Miller 2003; Welch 2003; Stumpf 2006. These studies challenged the law’s deportation and mandatory detention provisions, as well as its constraints on judicial review. And they exposed the law’s widespread consequences, namely the deportations that ensued and the disproportionate impact of IIRIRA’s enforcement measures on immigrants with longstanding ties to the United States (ABA 2004. Less is known about what drove IIRIRA’s criminal provisions or how immigration came to be viewed through a lens of criminality in the first place. Scholars have mostly looked within the immigration policy arena for

  19. "Alert-Audit-Act": assessment of surveillance and response strategy for malaria elimination in three low-endemic settings of Myanmar in 2016.

    Kyaw, Aye Mon Mon; Kathirvel, Soundappan; Das, Mrinalini; Thapa, Badri; Linn, Nay Yi Yi; Maung, Thae Maung; Lin, Zaw; Thi, Aung

    2018-01-01

    Myanmar, a malaria endemic country of Southeast Asia, adopted surveillance and response strategy similar to "1-3-7" Chinese strategy to achieve sub-national elimination in six low-endemic region/states of the country. Among these, Yangon, Bago-East, and Mon region/states have implemented this malaria surveillance and response strategy with modification in 2016. The current study was conducted to assess the case notification, investigation, classification, and response strategy (NICR) in these three states. This was a retrospective cohort study using routine program data of all patients with malaria diagnosed and reported under the National Malaria Control Programme in 2016 from the above three states. As per the program, all malaria cases need to be notified within 1 day and investigated within 3 days of diagnosis and response to control (active case detection and control) should be taken for all indigenous malaria cases within 7 days of diagnosis. A total of 959 malaria cases were diagnosed from the study area in 2016. Of these, the case NICR details were available only for 312 (32.5%) malaria cases. Of 312 cases, the case notification, investigation, and classification were carried out within 3 days of malaria diagnosis in 95.5% cases (298/312). Of 208 indigenous malaria cases (66.7%, 208/312), response to control was taken in 96.6% (201/208) within 7 days of diagnosis. The timeline at each stage of the strategy namely case notification, investigation, classification, and response to control was followed, and response action was taken in nearly all indigenous malaria cases for the available case information. Strengthening of health information and monitoring system is needed to avoid missing information. Future research on feasibility of mobile/tablet-based surveillance system and providing response to all cases including imported malaria can be further studied.

  20. Plans and schedules for implementation of US Nuclear Regulatory Commission responsibilities under the Low-Level Radioactive Waste Policy Amendments Act of 1985 (P.L. 99-240)

    Dunkelman, M.M.; Kearney, M.S.; MacDougall, R.D.

    1986-07-01

    The purpose of this document is to make available to the states and other interested parties, the plans and schedules for the US Nuclear Regulatory Commission's (NRC's) implementation of its responsibilities under Public Law 99-240, the Low-Level Radioactive Waste Policy Amendments Act of 1985 (LLRWPAA). This document identifies the provisions of the LLRWPAA which affect the programs of the NRC, identifies what the NRC must do to fulfill each of its requirements under the LLRWPAA, and establishes schedules for carrying out these requirements. The plans and schedules are current as of June 1986

  1. Two cis-acting elements responsible for posttranscriptional trans-regulation of gene expression of human T-cell leukemia virus type I

    Seiki, Motoharu; Inoue, Junichiro; Hidaka, Makoto; Yoshida, Mitsuaki

    1988-01-01

    The pX sequence of human T-cell leukemia virus type I codes for two nuclear proteins, p40 tax and p27 rex and a cytoplasmic protein, p21 X-III . p40 tax activates transcription from the long terminal repeat (LTR), whereas p27 rex modulates posttranscriptional processing to accumulate gag and env mRNAs that retain intron sequences. In this paper, the authors identify two cis-acting sequence elements needed for regulation by p27 rex : a 5' splice signal and a specific sequence in the 3' LTR. These two sequence elements are sufficient for regulation by p27 rex ; expression of a cellular gene (metallothionein I) became sensitive to rex regulation when the LTR was inserted at the 3' end of this gene. The requirement for these two elements suggests and unusual regulatory mechanism of RNA processing in the nucleus

  2. A 20 bp cis-acting element is both necessary and sufficient to mediate elicitor response of a maize PRms gene.

    Raventós, D; Jensen, A B; Rask, M B; Casacuberta, J M; Mundy, J; San Segundo, B

    1995-01-01

    Transient gene expression assays in barley aleurone protoplasts were used to identify a cis-regulatory element involved in the elicitor-responsive expression of the maize PRms gene. Analysis of transcriptional fusions between PRms 5' upstream sequences and a chloramphenicol acetyltransferase reporter gene, as well as chimeric promoters containing PRms promoter fragments or repeated oligonucleotides fused to a minimal promoter, delineated a 20 bp sequence which functioned as an elicitor-response element (ERE). This sequence contains a motif (-246 AATTGACC) similar to sequences found in promoters of other pathogen-responsive genes. The analysis also indicated that an enhancing sequence(s) between -397 and -296 is required for full PRms activation by elicitors. The protein kinase inhibitor staurosporine was found to completely block the transcriptional activation induced by elicitors. These data indicate that protein phosphorylation is involved in the signal transduction pathway leading to PRms expression.

  3. AguR is a transmembrane transcription activator of the putrescine biosynthesis operon in Lactococcus lactis, and acts in response to agmatine concentration

    Linares, Daniel M; Del Rio, Beatriz; Redruello, Begoña; Ladero, Victor; Martin, Ma Cruz; de Jong, Anne; Kuipers, Oscar P; Fernandez, Maria; Alvarez, Miguel A

    2015-01-01

    Dairy industry fermentative processes mostly use Lactococcus lactis as a starter. However, some dairy L. lactis strains produce putrescine - a biogenic amine that raises food safety and spoilage concerns - via the agmatine deiminase pathway (AGDI). The enzymatic activities responsible for putrescine

  4. Self-acting shaft seals

    Ludwig, L. P.

    1978-01-01

    Self-acting seals are described in detail. The mathematical models for obtaining a seal force balance and the equilibrium operating film thickness are outlined. Particular attention is given to primary ring response (seal vibration) to rotating seat face runout. This response analysis reveals three different vibration models with secondary seal friction being an important parameter. Leakage flow inlet pressure drop and affects of axisymmetric sealing face deformations are discussed. Experimental data on self-acting face seals operating under simulated gas turbine conditions are given. Also a spiral groove seal design operated to 244 m/sec (800 ft/sec) is described.

  5. Atomic Energy Commission Act, 2000 (Act 588)

    2000-01-01

    Act 588 of the Republic of Ghana entitled, Atomic Energy Commission Act, 2000, amends and consolidates the Atomic Energy Commission Act, 204 of 1963 relating to the establishment of the Atomic Energy Commission. Act 588 makes provision for the Ghana Atomic Energy Commission to establish more institutes for the purpose of research in furtherance of its functions and also promote the commercialization of its research and development results. (E.A.A.)

  6. Opportunities for Energy Development in Water Conduits: A Report Prepared in Response to Section 7 of the Hydropower Regulatory Efficiency Act of 2013

    Sale, Michael J. [BCS, Incorporated, Laurel, MD (United States); Bishop, Norman A. [Knight Piesold, Chicago, IL (United States); Reiser, Sonya L. [Knight Piesold, Chicago, IL (United States); Johnson, Kurt [Telluride Energy LLC, Grand Junction, CO (United States); Bailey, Andrea C. [BCS, Incorporated, Laurel, MD (United States); Frank, Anthony [BCS, Incorporated, Laurel, MD (United States); Smith, Brennan T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Environmental Sciences Division

    2014-09-01

    In Section 7 of the Hydropower Regulatory Efficiency Act (HREA) of 2013 (P.L. 113-23), Congress directed the U.S. Department of Energy (DOE) to prepare an analysis of conduit hydropower opportunities available in the United States and to present case studies that describe the potential energy generation from these types of hydropower projects. Those analyses have been included in a new DOE report to Congress, and this ORNL/TM provides additional technical details supporting that report. Conduit hydropower offers important new ways to enhance renewable energy portfolios in the United States, as well as to increase the energy efficiency of water delivery systems. Conduit hydropower projects are constructed on existing water-conveyance structures, such as irrigation canals or pressurized pipelines that deliver water to municipalities, industry, or agricultural water users. Although water conveyance infrastructures are usually designed for non-power purposes, new renewable energy can often be harvested from them without affecting their original purpose and without the need to construct new dams or diversions. Conduit hydropower differs from more conventional hydropower development in that it is generally not located on natural rivers or waterways and therefore does not involve the types of environmental impacts that are associated with hydropower. The addition of hydropower to existing water conduits can provide valuable new revenue sources from clean, renewable energy. The new energy can be used within the existing water distribution systems to offset other energy demands, or it can be sold into regional transmission systems.

  7. Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid Remifentanil in humans

    Schalling Martin; Lonsdorf Tina B; Jensen Karin B; Kosek Eva; Ingvar Martin

    2009-01-01

    Abstract Background There is evidence from animal studies that serotonin (5-HT) can influence the antinociceptive effects of opioids at the spinal cord level. Therefore, there could be an influence of genetic polymorphisms in the serotonin system on individual variability in response to opioid treatment of pain. The serotonin transporter (5-HTT) is a key regulator of serotonin metabolism and availability and its gene harbors several known polymorphisms that are known to affect 5-HTT expressio...

  8. SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65

    Pengcheng Li

    2018-04-01

    Full Text Available Dengue virus (DENV is a mosquito-borne single-stranded RNA virus causing human disease with variable severity. The production of massive inflammatory cytokines in dengue patients has been associated with dengue disease severity. However, the regulation of these inflammatory responses remains unclear. In this study, we report that SIRT6 is a negative regulator of innate immune responses during DENV infection. Silencing of Sirt6 enhances DENV-induced proinflammatory cytokine and chemokine production. Overexpression of SIRT6 inhibits RIG-I-like receptor (RLR and Toll-like receptor 3 (TLR3 mediated NF-κB activation. The sirtuin core domain of SIRT6 is required for the inhibition of NF-κB p65 function. SIRT6 interacts with the DNA binding domain of p65 and competes with p65 to occupy the Il6 promoter during DENV infection. Collectively, our study demonstrates that SIRT6 negatively regulates DENV-induced inflammatory response via RLR and TLR3 signaling pathways.

  9. American Recovery and Reinvestment Act of 2009. Interim Report on Customer Acceptance, Retention, and Response to Time-Based Rates from the Consumer Behavior Studies

    Cappers, Peter [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Hans, Liesel [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Scheer, Richard [Scheer Ventures, Takoma Park, MD (United States)

    2015-06-01

    Time-based rate programs1, enabled by utility investments in advanced metering infrastructure (AMI), are increasingly being considered by utilities as tools to reduce peak demand and enable customers to better manage consumption and costs. There are several customer systems that are relatively new to the marketplace and have the potential for improving the effectiveness of these programs, including in-home displays (IHDs), programmable communicating thermostats (PCTs), and web portals. Policy and decision makers are interested in more information about customer acceptance, retention, and response before moving forward with expanded deployments of AMI-enabled new rates and technologies. Under the Smart Grid Investment Grant Program (SGIG), the U.S. Department of Energy (DOE) partnered with several utilities to conduct consumer behavior studies (CBS). The goals involved applying randomized and controlled experimental designs for estimating customer responses more precisely and credibly to advance understanding of time-based rates and customer systems, and provide new information for improving program designs, implementation strategies, and evaluations. The intent was to produce more robust and credible analysis of impacts, costs, benefits, and lessons learned and assist utility and regulatory decision makers in evaluating investment opportunities involving time-based rates. To help achieve these goals, DOE developed technical guidelines to help the CBS utilities estimate customer acceptance, retention, and response more precisely.

  10. Interaction between two cis-acting elements, ABRE and DRE, in ABA-dependent expression of Arabidopsis rd29A gene in response to dehydration and high-salinity stresses.

    Narusaka, Yoshihiro; Nakashima, Kazuo; Shinwari, Zabta K; Sakuma, Yoh; Furihata, Takashi; Abe, Hiroshi; Narusaka, Mari; Shinozaki, Kazuo; Yamaguchi-Shinozaki, Kazuko

    2003-04-01

    Many abiotic stress-inducible genes contain two cis-acting elements, namely a dehydration-responsive element (DRE; TACCGACAT) and an ABA-responsive element (ABRE; ACGTGG/TC), in their promoter regions. We precisely analyzed the 120 bp promoter region (-174 to -55) of the Arabidopsis rd29A gene whose expression is induced by dehydration, high-salinity, low-temperature, and abscisic acid (ABA) treatments and whose 120 bp promoter region contains the DRE, DRE/CRT-core motif (A/GCCGAC), and ABRE sequences. Deletion and base substitution analyses of this region showed that the DRE-core motif functions as DRE and that the DRE/DRE-core motif could be a coupling element of ABRE. Gel mobility shift assays revealed that DRE-binding proteins (DREB1s/CBFs and DREB2s) bind to both DRE and the DRE-core motif and that ABRE-binding proteins (AREBs/ABFs) bind to ABRE in the 120 bp promoter region. In addition, transactivation experiments using Arabidopsis leaf protoplasts showed that DREBs and AREBs cumulatively transactivate the expression of a GUS reporter gene fused to the 120 bp promoter region of rd29A. These results indicate that DRE and ABRE are interdependent in the ABA-responsive expression of the rd29A gene in response to ABA in Arabidopsis.

  11. On the relative importance of loads acting on a floating vertical axis wind turbine system when evaluating the global system response

    Collu, Maurizio; Borg, Michael; Manuel, Lance

    2016-01-01

    Interest in offshore floating wind turbines has been growing over the last decade. While a number of studies have been conducted to model the dynamics of offshore floating HAWT systems (e.g. OC3-Phase IV, OC4-Phase II), relatively few studies have been conducted on floating VAWT systems, despite...... offshore floating VAWT, considering a turbulent wind field and stochastically generated waves, to assess the more critical loads and distinguish them from those with negligible effect, when estimating the global system response. The floating VAWT system considered is comprised of a 5MW rotor supported...

  12. Oxygen sensors and energy sensors act synergistically to achieve a graded alteration in gene expression: consequences for assessing the level of neuroprotection in response to stressors.

    Renshaw, Gillian M C; Warburton, Joshua; Girjes, Adeeb

    2004-01-01

    Changes in gene expression are associated with switching to an autoprotected phenotype in response to environmental and physiological stress. Ubiquitous molecular chaperones from the heat shock protein (HSP) superfamily confer neuronal protection that can be blocked by antibodies. Recent research has focused on the interactions between the molecular sensors that affect the increased expression of neuroprotective HSPs above constitutive levels. An examination of the conditions under which the expression of heat shock protein 70 (Hsp70) was up regulated in a hypoxia and anoxia tolerant tropical species, the epaulette shark (Hemiscyllium ocellatum), revealed that up-regulation was dependent on exceeding a stimulus threshold for an oxidative stressor. While hypoxic-preconditioning confers neuroprotective changes, there was no increase in the level of Hsp70 indicating that its increased expression was not associated with achieving a neuroprotected state in response to hypoxia in the epaulette shark. Conversely, there was a significant increase in Hsp70 in response to anoxic-preconditioning, highlighting the presence of a stimulus threshold barrier and raising the possibility that, in this species, Hsp70 contributes to the neuroprotective response to extreme crises, such as oxidative stress. Interestingly, there was a synergistic effect of coincident stressors on Hsp70 expression, which was revealed when metabolic stress was superimposed upon oxidative stress. Brain energy charge was significantly lower when adenosine receptor blockade, provided by treatment with aminophylline, was present prior to the final anoxic episode, under these circumstances, the level of Hsp70 induced was significantly higher than in the pair-matched saline treated controls. An understanding of the molecular and metabolic basis for neuroprotective switches, which result in an up-regulation of neuroprotective Hsp70 expression in the brain, is needed so that intervention strategies can be devised

  13. Forced Migration and Global Responsibility for Health Comment on "Defining and Acting on Global Health: The Case of Japan and the Refugee Crisis".

    Bozorgmehr, Kayvan; Razum, Oliver

    2016-11-05

    Forced migration has become a world-wide phenomenon in the past century, affecting increasing numbers of countries and people. It entails important challenges from a global health perspective. Leppold et al have critically discussed the Japanese interpretation of global responsibility for health in the context of forced migration. This commentary complements their analysis by outlining three priority areas of global health responsibility for European Union (EU) countries. We highlight important stages of the migration phases related to forced migration and propose three arguments. First, the chronic neglect of the large number of internally displaced persons (IDPs) in the discourses on the "refugee crisis" needs to be corrected in order to develop sustainable solutions with a framework of the Sustainable Development Goals (SDGs). Second, protection gaps in the global system of protection need to be effectively closed to resolve conflicts with border management and normative global health frameworks. Third, effective policies need to be developed and implemented to meet the health and humanitarian needs of forced migrants; at the same time, the solidarity crisis within the EU needs to be overcome. These stakes are high. EU countries, being committed to global health, should urgently address these areas. © 2017 The Author(s); Published by Kerman University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

  14. Forced Migration and Global Responsibility for Health; Comment on “Defining and Acting on Global Health: The Case of Japan and the Refugee Crisis”

    Kayvan Bozorgmehr

    2017-07-01

    Full Text Available Forced migration has become a world-wide phenomenon in the past century, affecting increasing numbers of countries and people. It entails important challenges from a global health perspective. Leppold et al have critically discussed the Japanese interpretation of global responsibility for health in the context of forced migration. This commentary complements their analysis by outlining three priority areas of global health responsibility for European Union (EU countries. We highlight important stages of the migration phases related to forced migration and propose three arguments. First, the chronic neglect of the large number of internally displaced persons (IDPs in the discourses on the “refugee crisis” needs to be corrected in order to develop sustainable solutions with a framework of the Sustainable Development Goals (SDGs. Second, protection gaps in the global system of protection need to be effectively closed to resolve conflicts with border management and normative global health frameworks. Third, effective policies need to be developed and implemented to meet the health and humanitarian needs of forced migrants; at the same time, the solidarity crisis within the EU needs to be overcome. These stakes are high. EU countries, being committed to global health, should urgently address these areas.

  15. Amplification of the Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 lytic origin of DNA replication is dependent upon a cis-acting AT-rich region and an ORF50 response element and the trans-acting factors ORF50 (K-Rta) and K8 (K-bZIP)

    AuCoin, David P.; Colletti, Kelly S.; Cei, Sylvia A.; Papouskova, Iva; Tarrant, Margaret; Pari, Gregory S.

    2004-01-01

    Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), has significant sequence homology to Epstein-Barr virus (EBV). In cell culture, HHV8 is primarily latent, and viral genes associated with lytic replication are not expressed. Two lytic origins of DNA replication (oriLyt) are present within the HHV8 genome and are composed of an AT-rich region adjacent to GC-rich DNA sequences. We have now identified essential cis- and trans-acting elements required for oriLyt-dependent DNA replication. The transient replication assay was used to show that two AT-rich elements, three consensus AP1 transcription factor-binding sites, an ORF50 response element (RE), and a consensus TATA box motif are essential for efficient origin-dependent DNA replication. Transient transfection of luciferase reporter constructs indicated that the downstream region of the HHV8 oriLyt responds to ORF50 and suggests that part of the oriLyt may be an enhancer/promoter. In addition, a transient cotransfection-replication assay elucidated the set of trans-acting factors required for lytic DNA replication. These factors consist of homologues to the core replication proteins: ORF6 (ssDNA binding protein), ORF9 (DNA polymerase), ORF40-41 (primase-associated factor), ORF44 (helicase), ORF56 (primase), and ORF59 (polymerase processivity factor) common to all herpesviruses along with ORF50 (K-Rta) and K8 (K-bZIP)

  16. Interferon-inducible transmembrane proteins of the innate immune response act as membrane organizers by influencing clathrin and v-ATPase localization and function.

    Wee, Yin Shen; Roundy, Kirstin M; Weis, Janis J; Weis, John H

    2012-12-01

    The innate response interferon-inducible transmembrane (Ifitm) proteins have been characterized as influencing proliferation, signaling complexes and restricting virus infections. Treatment of cells lacking these proteins (IfitmDel) with IFN-β resulted in the loss of clathrin from membrane compartments and the inhibition of clathrin-mediated phagocytosis, suggesting a molecular interaction between clathrin and Ifitm proteins. The pH of endosomes of IfitmDel cells, with or without IFN activation, was neutralized, suggesting the function of the vacular ATPase proton pumps in such cells was compromised. Co-immunoprecipitation of Ifitm3 with Atp6v0b demonstrated a direct interaction between the Ifitm proteins and the v-ATPase. These data suggest that the Ifitm proteins help stabilize v-ATPase complexes in cellular membranes which, in turn, facilitates the appropriate subcellular localization of clathrin.

  17. American Recovery and Reinvestment Act of 2009: Final Report on Customer Acceptance, Retention, and Response to Time-Based Rates from Consumer Behavior Studies

    Cappers, Peter [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Energy Analysis and Environmental Impacts Division; Scheer, Rich [Scheer Ventures LLC, Takoma Park, MD (United States)

    2018-03-07

    Time-based rate programs, enabled by utility investments in advanced metering infrastructure (AMI), are increasingly being considered by utilities as tools to reduce peak demand and enable customers to better manage consumption and costs. Under the Smart Grid Investment Grant Program (SGIG), the U.S. Department of Energy (DOE) partnered with several electric utilities to conduct consumer behavior studies (CBS). The goals involved applying randomized and controlled experimental designs for estimating customer responses more precisely and credibly to advance understanding of time-based rates and customer systems, and provide new information for improving program designs, implementation strategies, and evaluations. The intent was to produce more robust and credible analysis of impacts, costs, benefits, and lessons learned and assist utility and regulatory decision makers in evaluating investment opportunities involving time-based rates.

  18. Nuclear Regulatory Authority Act, 2015 (Act 895)

    2015-04-01

    An Act to establish a Nuclear Regulatory Authority in Ghana. This Act provides for the regulation and management of activities and practices for the peaceful use of nuclear material or energy, and to provide for the protection of persons and the environment against the harmful effects of radiation; and to ensure the effective implementation of the country’s international obligations and for related matters. This Act replaced the Radiation Protection Instrument, of 1993 (LI 1559).

  19. Defining the role of risk assessment in the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) remedial investigation process at the DOE-OR

    Miller, P.D.; McGinn, C.W.; Purucker, S.T.; White, R.K.

    1994-08-01

    The risk assessment strategy that will be implemented on the Oak Ridge Reservation has been standardized to ensure consistency and technical defensibility in all risk assessment activities and is presented within this document. The strategy emphasizes using existing environmental data in screening risk analyses to aid in identifying chemicals of potential concern, operable units that could pursue a no further investigation determination, and operable units that may warrant early response actions. The screening risk analyses include a comparison of measured chemical concentrations to preliminary remediation goals, performing a most likely exposure and integration point assessment, and performing a screening ecological risk assessment. This document focuses heavily on the screening risk analyses and relies on existing U.S. Environmental Protection Agency risk assessment guidance to provide specific details on conducting baseline risk assessments. However, the document does contain a section on the baseline risk assessment process that details the exposure pathways to be evaluated on the Oak Ridge Reservation. This document will be used in conjunction with existing Martin Marietta Energy Systems, Inc. Environmental Restoration risk assessment standards, policies, procedures, and technical memoranda. The material contained herein will be periodically updated as the strategy is tried and tested and as the risk assessment methodology is revised. The primary purpose for this document is to present the proposed strategy to the Tennessee Department of Environment and Conservation and the U.S. Environmental Protection Agency, Region IV and receive concurrence or additional comments on the material presented herein

  20. The anti-Müllerian hormone (AMH) acts as a gatekeeper of ovarian steroidogenesis inhibiting the granulosa cell response to both FSH and LH.

    Sacchi, Sandro; D'Ippolito, Giovanni; Sena, Paola; Marsella, Tiziana; Tagliasacchi, Daniela; Maggi, Elena; Argento, Cindy; Tirelli, Alessandra; Giulini, Simone; La Marca, Antonio

    2016-01-01

    Anti Müllerian Hormone (AMH) has a negative and inhibitory role in many functions of human granulosa-lutein cells (hGCs) including notoriously the reduction of the aromatase CYP19A1 expression induced by follicle-stimulating hormone (FSH). No data have been provided on the possible role of AMH in modulating the response to luteinizing hormone (LH) (alone or combined with FSH) as well as its effect on other enzymes involved in steroidogenesis including aromatase P450scc. The aim of this study was to investigate the role of AMH as regulator of the basal and stimulated steroids production by hGCs. Primary culture of hGCs were incubated with hormones AMH, LH, and FSH, alone or in combination. The CYP19A1 and P450scc messenger RNA (mRNA) expression, normalized by housekeeping ribosomal protein S7 (RpS7) gene, was evaluated by reverse transcriptase quantitative PCR (RT-qPCR). Each reaction was repeated in triplicate. Negative controls using corresponding amount of vehicle control for each hormone treatment were performed. AMH did not modulate the basal mRNA expression of both aromatase genes at any of the concentrations tested. Meanwhile, the strong mRNA induction of CYP19A1 and P450scc generated by a 24-h gonadotropin treatment (alone and combined) was suppressed by 20 ng/ml AMH added to culture medium. These findings contribute in clarifying the relationship between hormones regulating the early phase of steroidogenesis confirming that AMH is playing a suppressive role on CYP19A1 expression stimulated by gonadotropin in hGCs. Furthermore, a similar inhibitory effect for AMH was observed on P450scc gene expression when activated by gonadotropin treatment.

  1. DisA and c-di-AMP act at the intersection between DNA-damage response and stress homeostasis in exponentially growing Bacillus subtilis cells.

    Gándara, Carolina; Alonso, Juan C

    2015-03-01

    Bacillus subtilis contains two vegetative diadenylate cyclases, DisA and CdaA, which produce cyclic di-AMP (c-di-AMP), and one phosphodiesterase, GdpP, that degrades it into a linear di-AMP. We report here that DisA and CdaA contribute to elicit repair of DNA damage generated by alkyl groups and H2O2, respectively, during vegetative growth. disA forms an operon with radA (also termed sms) that encodes a protein distantly related to RecA. Among different DNA damage agents tested, only methyl methane sulfonate (MMS) affected disA null strain viability, while radA showed sensitivity to all of them. A strain lacking both disA and radA was as sensitive to MMS as the most sensitive single parent (epistasis). Low c-di-AMP levels (e.g. by over-expressing GdpP) decreased the ability of cells to repair DNA damage caused by MMS and in less extent by H2O2, while high levels of c-di-AMP (absence of GdpP or expression of sporulation-specific diadenylate cyclase, CdaS) increased cell survival. Taken together, our results support the idea that c-di-AMP is a crucial signalling molecule involved in DNA repair with DisA and CdaA contributing to modulate different DNA damage responses during exponential growth. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ultra-Long-Acting Insulin.

    Moser, Othmar; Tschakert, Gerhard; Mueller, Alexander; Groeschl, Werner; Pieber, Thomas R; Obermayer-Pietsch, Barbara; Koehler, Gerd; Hofmann, Peter

    2015-01-01

    We investigated blood glucose (BG) and hormone response to aerobic high-intensity interval exercise (HIIE) and moderate continuous exercise (CON) matched for mean load and duration in type 1 diabetes mellitus (T1DM). Seven trained male subjects with T1DM performed a maximal incremental exercise test and HIIE and CON at 3 different mean intensities below (A) and above (B) the first lactate turn point and below the second lactate turn point (C) on a cycle ergometer. Subjects were adjusted to ultra-long-acting insulin Degludec (Tresiba/ Novo Nordisk, Denmark). Before exercise, standardized meals were administered, and short-acting insulin dose was reduced by 25% (A), 50% (B), and 75% (C) dependent on mean exercise intensity. During exercise, BG, adrenaline, noradrenaline, dopamine, cortisol, glucagon, and insulin-like growth factor-1, blood lactate, heart rate, and gas exchange variables were measured. For 24 h after exercise, interstitial glucose was measured by continuous glucose monitoring system. BG decrease during HIIE was significantly smaller for B (p = 0.024) and tended to be smaller for A and C compared to CON. No differences were found for post-exercise interstitial glucose, acute hormone response, and carbohydrate utilization between HIIE and CON for A, B, and C. In HIIE, blood lactate for A (p = 0.006) and B (p = 0.004) and respiratory exchange ratio for A (p = 0.003) and B (p = 0.003) were significantly higher compared to CON but not for C. Hypoglycemia did not occur during or after HIIE and CON when using ultra-long-acting insulin and applying our methodological approach for exercise prescription. HIIE led to a smaller BG decrease compared to CON, although both exercises modes were matched for mean load and duration, even despite markedly higher peak workloads applied in HIIE. Therefore, HIIE and CON could be safely performed in T1DM. ClinicalTrials.gov NCT02075567 http://www.clinicaltrials.gov/ct2/show/NCT02075567.

  3. Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ultra-Long-Acting Insulin.

    Othmar Moser

    Full Text Available We investigated blood glucose (BG and hormone response to aerobic high-intensity interval exercise (HIIE and moderate continuous exercise (CON matched for mean load and duration in type 1 diabetes mellitus (T1DM.Seven trained male subjects with T1DM performed a maximal incremental exercise test and HIIE and CON at 3 different mean intensities below (A and above (B the first lactate turn point and below the second lactate turn point (C on a cycle ergometer. Subjects were adjusted to ultra-long-acting insulin Degludec (Tresiba/ Novo Nordisk, Denmark. Before exercise, standardized meals were administered, and short-acting insulin dose was reduced by 25% (A, 50% (B, and 75% (C dependent on mean exercise intensity. During exercise, BG, adrenaline, noradrenaline, dopamine, cortisol, glucagon, and insulin-like growth factor-1, blood lactate, heart rate, and gas exchange variables were measured. For 24 h after exercise, interstitial glucose was measured by continuous glucose monitoring system.BG decrease during HIIE was significantly smaller for B (p = 0.024 and tended to be smaller for A and C compared to CON. No differences were found for post-exercise interstitial glucose, acute hormone response, and carbohydrate utilization between HIIE and CON for A, B, and C. In HIIE, blood lactate for A (p = 0.006 and B (p = 0.004 and respiratory exchange ratio for A (p = 0.003 and B (p = 0.003 were significantly higher compared to CON but not for C.Hypoglycemia did not occur during or after HIIE and CON when using ultra-long-acting insulin and applying our methodological approach for exercise prescription. HIIE led to a smaller BG decrease compared to CON, although both exercises modes were matched for mean load and duration, even despite markedly higher peak workloads applied in HIIE. Therefore, HIIE and CON could be safely performed in T1DM.ClinicalTrials.gov NCT02075567 http://www.clinicaltrials.gov/ct2/show/NCT02075567.

  4. Daily Administration of Short-Acting Liothyronine Is Associated with Significant Triiodothyronine Excursions and Fails to Alter Thyroid-Responsive Parameters.

    Jonklaas, Jacqueline; Burman, Kenneth D

    2016-06-01

    Although most studies of levothyroxine-liothyronine combination therapy employ once-daily hormone administration, the kinetics of once-daily liothyronine have been studied infrequently. The aim of this study was to document both the peak and trough serum triiodothyronine (T3) levels that occur with once-daily liothyronine administration, along with changes in thyroid-responsive parameters. Participants with hypothyroidism were studied prospectively at an academic institution. Patients were switched from levothyroxine monotherapy to liothyronine monotherapy with 15 μg liothyronine for two weeks, and then continued liothyronine at doses of 30-45 μg for a further four weeks in an open-label, single-arm study. Weekly trough levels of T3 were documented. In addition, hourly T3 concentrations immediately following liothyronine tablet administration were documented for eight hours during the sixth week of therapy. Serum thyrotropin (TSH) and free thyroxine (fT4) concentrations were documented. Biochemical markers, markers of energy metabolism, anthropometric parameters, well-being, and hyperthyroid symptoms were also assessed. Mean serum TSH levels increased from 1.56 ± 0.81 mIU/L at baseline to 5.90 ± 5.74 mIU/L at two weeks and 3.84 ± 3.66 mIU/L at six weeks. Trough T3 levels decreased from 99.5 ± 22.9 to 91.9 ± 40.2 at two weeks and recovered to 96.1 ± 32.2 at six weeks. The peak T3 concentration after dosing of liothyronine during week 6 was 292.8 ± 152.3 ng/dL. fT4 levels fell once levothyroxine was discontinued and plateaued at 0.44 ng/dL at week 4. The sex hormone binding globulin (SHBG) concentration decreased at week 2 (p = 0.002). Hyperthyroid symptoms and SF36-PCS scores increased significantly at weeks 4-5 of liothyronine therapy (p = 0.04-0.005). Preference for liothyronine therapy increased from 6% to 39% over the study period. Once-daily dosing of liothyronine at doses of 30-45 μg did not return serum

  5. Atomic Act amended

    Drabova, D.

    2002-01-01

    In the paper by the chairwoman of the Czech nuclear regulatory authority, the history of Czech nuclear legislation is outlined, the reasons for the amendment of the Atomic Act (Act No. 18/1997) are explained, and the amendments themselves are highlighted. The Act No. 13/2002 of 18 December 2001 is reproduced from the official Collection of Acts of the Czech Republic in the facsimile form. The following acts were thereby amended: Atomic Act No. 18/1997, Metrology Act No. 505/1990, Public Health Protection Act No. 258/2000, and Act No. 2/1969 on the Establishment of Ministries and Other Governmental Agencies of the Czech Republic. (P.A.)

  6. Thinking and acting strategically: promoting integrated solid waste management and corporate responsibility through a public private partnership; the case of Altamira, Tamaulipas, Mexico

    Bernhard Bösl

    2010-09-01

    Full Text Available This article provides an assessment of a public private partnerships (PPP among the German Technical Cooperation (GTZ, the Municipality of Altamira, Tamaulipas, Mexico and private counterparts BASF Mexicana and Terminal de LNG de Altamira (TLA. The municipality of Altamira, located in the urban-industrial hub of southern Tamaulipas, Mexico, faces important challenges in the field of urban public service delivery, particularly waste management, due to a high demographic growth rate and chronic budgetary constraints. The partnership was formed as a means to develop and implement the Municipal Program for the Prevention and Integrated Management of Solid and Special Wastes. The paper discusses the efficacy of the PPP as a policy instrument for the implementation of integrated solid waste management. As an assessment method, the authors draw on GTZ’s success criteria for the cooperation with the private sector. Criteria include the degree of complementarity, subsidiarity, neutrality and quality of private sector contributions. We argue that this PPP displays a pioneering alliance structure, since the private sector becomes a direct ally in creating strategies for the promotion sustainable development and not simply an exclusive contractor for urban public services delivery or a recipient of incentives from international development cooperation. The PPP provides a means to reach corporate social and environmental responsibility goals while at the same time it promotes development-related policy goals enshrined in the bilateral cooperation agreement between Germany and Mexico. However, the alliance faces important challenges related to different organizational cultures, electoral times and citizen participation.Cet article évalue un partenariat public-privé (PPP entre GTZ (société allemande de coopération technique, la municipalité d’Altamira, dans l’état du Tamaulipas au Mexique et deux homologues privés : BASF Mexicana et Terminal de

  7. Radiation Safety Act 1975 - No 44 of 1975

    1975-01-01

    This Act regulates the use of radioactive substances and irradiating apparatus, including particle accelerators as well as certain specified electronic products. The Act lays down a licensing and registration system for such substances and apparatus; it sets up a Radiological Council to administer the Act and to advise the Minister responsible for public health on matters of radiation safety. The radioactive Substances Act 1954 and the Amending Acts of 1960 and 1964 are repealed. (NEA) [fr

  8. Airway Clearance Techniques (ACTs)

    Full Text Available ... Therapeutics Lab Developing New Treatments The CF Foundation offers a number of resources for learning about clinical ... her father: Demonstrate and discuss common ACT therapies Offer their tips for fitting ACTs into daily life ...

  9. Airway Clearance Techniques (ACTs)

    Full Text Available ... Treatments and Therapies Airway Clearance Airway Clearance Techniques (ACTs) There are different ways to clear your airways. ... or caregiver. Older kids and adults can choose ACTs that they can do on their own. Share ...

  10. Nuclear Installations Act 1965

    1965-01-01

    This Act governs all activities related to nuclear installations in the United Kingdom. It provides for the licensing procedure for nuclear installations, the duties of licensees, the competent authorities and carriers of nuclear material in respect of nuclear occurrences, as well as for the system of third party liability and compensation for nuclear damage. The Act repeals the Nuclear Installations (Licensing and Insurance) Act 1959 and the Nuclear Installations (Amendment Act) 1965 except for its Section 17(2). (NEA) [fr

  11. Self-acting and hydrodynamic shaft seals

    Ludwig, L. P.

    1973-01-01

    Self-acting and hydrodynamic seals are described. The analytical procedures are outlined for obtaining a seal force balance and the operating film thickness. Particular attention is given to primary ring response (seal vibration) to rotating seat face runout. This response analysis revealed three different vibration modes. Proposed applications of self-acting seals in gas turbine engines and in rocket vehicle turbopumps are described. Also experimental data on self-acting face seals operating under simulated gas turbine conditions are given; these data show the feasibility of operating the seal at conditions of 345 newtons per square centimeter (500 psi) and 152 meters per second (500 ft/sec) sliding speed.

  12. Tenth act amending the German atomic energy act

    Heller, W.

    2009-01-01

    On January 14, 2009, the German federal government introduced into parliament the 10th Act Amending the Atomic Energy Act. In the first reading in the federal parliament, Federal Minister for the Environment Gabriel emphasized 2 main points: Intensified protection of nuclear facilities and of transports of radioactive substances against unauthorized interventions; transfer by law to the Federal Office for Radiological Protection (BfS) of decommissioning of the Asse mine. Reliability review: The amendment to Sec.12 b of the Atomic Energy Act is to meet the different safety and security conditions after the terrorist attacks on September 11, 2001 in the United States and other terrorist activities afterwards (London, Madrid) also with respect to hazards arising to nuclear facilities and nuclear transports. The bill must be seen in conjunction with the Ordinance on Reliability Reviews under the Atomic Energy Act dated July 1, 1999 which covers reviews of reliability of persons holding special responsibilities. Asse II mine: The competence of the Federal Office for Radiological Protection is achieved by an amendment to Sec.23, Para.1, Number 2, Atomic Energy Act, in which the words ''and for the Asse II mine'' are added after the word ''waste.'' Further proceedings depend on the additional provision in a new Sec.57 b, Atomic Energy Act. Accordingly, the operation and decommissioning of the Asse II mine are subject to the regulations applicable to facilities of the federation pursuant to Sec.9a, Para.3. In this way, Asse II is given the same legal status as the federal waste management facilities. Moreover, it is stipulated that the mine is to be shut down immediately. (orig.)

  13. Hazardous materials management and compliance training

    Dalton, T.F.

    1991-01-01

    OSHA training for hazardous waste site workers is required by the Superfund Amendments and Reauthorization Act of 1986 (SARA). In December 1986, a series of regulations was promulgated by OSHA on an interim basis calling for the training of workers engaged in hazardous waste operations. Subsequent to these interim regulations, final rules were promulgated and these final rules on hazardous waste operations and emergency response became effective on March 6, 1990. OSHA has conducted hearings on the accreditation of training programs. OSHA would like to follow the accreditation process under the AHERA regulations for asbestos, in which the model plan for accreditation of asbestos abatement training was included in Section 206 of Title 11 of the Toxic Substance Control Act (TSCA). OSHA proposed on January 26, 1990, to perform the accreditation of training programs for hazardous waste operations and that proposal suggested that they follow the model plan similar to the one used for AHERA. They did not propose to accredited training programs for workers engaged in emergency response. These new regulations pose a significant problem to the various contractors and emergency responders who deal with hazardous materials spill response, cleanup and site remediation since these programs have expanded so quickly that many people are not familiar with what particular segment of the training they are required to have and whether or not programs that have yet to be accredited are satisfactory for this type of training. Title III of SARA stipulates a training program for first responders which includes local emergency response organizations such as firemen and policemen. The purpose of this paper is to discuss the needs of workers at hazardous waste site remediation projects and workers who are dealing with hazardous substances, spill response and cleanup

  14. Radioactive Substances Act 1960

    1960-01-01

    This Act regulates the keeping and use of radioactive material and makes provision for the disposal and storage of radioactive waste in the United Kingdom. It provides for a licensing system for such activities and for exemptions therefrom, in particular as concerns the United Kingdom Atomic Energy Authority. The Act repeals Section 4(5) of the Atomic Energy Authority Act, 1954 which made temporary provision for discharge of waste on or from premises occupied by the Authority. (NEA) [fr

  15. Learning dialog act processing

    Wermter, Stefan; Löchel, Matthias

    1996-01-01

    In this paper we describe a new approach for learning dialog act processing. In this approach we integrate a symbolic semantic segmentation parser with a learning dialog act network. In order to support the unforeseeable errors and variations of spoken language we have concentrated on robust data-driven learning. This approach already compares favorably with the statistical average plausibility method, produces a segmentation and dialog act assignment for all utterances in a robust manner,...

  16. Airway Clearance Techniques (ACTs)

    Full Text Available ... Reform Could Impact People With CF The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy Achievements Advocacy News Briefings, Testimonies, and Regulatory ...

  17. 25 CFR 700.33 - Act (The Act).

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Act (The Act). 700.33 Section 700.33 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.33 Act (The Act). (a) The Act. The Act is Pub. L. 93-531, (88 Stat...

  18. State Implementation and Perceptions of Title I School Improvement Grants under the Recovery Act: One Year Later. Online Appendix--State Responses to Open-Ended Questions about the ARRA SIG Program

    Center on Education Policy, 2012

    2012-01-01

    To learn more about states' experiences with implementing school improvement grants (SIGs) funded through the American Recovery and Reinvestment Act (ARRA), the Center on Education Policy (CEP) administered a survey to state Title I directors. (Title I of the Elementary and Secondary Education Act provides federal funds to schools in low-income…

  19. 48 CFR 304.604 - Responsibilities.

    2010-10-01

    ... and ensure compliance with the Federal Funding Accountability and Transparency Act (Transparency Act... organizational roles and responsibilities associated with contract reporting, including data input, oversight...

  20. Act No 282 reorganising ENEA

    1991-01-01

    This Act reorganises the National Agency for Research and Development of Nuclear and Alternative Energies - ENEA - and reorients its responsibilities. It is now called the National Agency for New Technologies, Energy and the Environment and retains its acronym (Ente per le nouve tecnologies, l'energia e l'ambiente - ENEA). It will also deal with environmental questions and new technologies, in particular, carrying out studies and research on the latter and evaluating their economic, social and environmental consequences. Already in 1982, the National Nuclear Energy Committee (CNEN) had been entrusted with wider tasks and renamed ENEA. The present ENEA retains its competence regarding nuclear activities, notably in the field of nuclear safety and radiation protection. The new Act confirms the tasks already conferred on the Nuclear Safety and Health Protection Directorate (DISP), we well as its operational independence while remaining within ENEA [fr

  1. Marine Mammal Protection Act

    National Oceanic and Atmospheric Administration, Department of Commerce — The Marine Mammal Protection Act (MMPA or Act) prohibits, with certain exceptions, the "take" of marine mammals in U.S. waters and by U.S. citizens on the high seas,...

  2. Collective speech acts

    Meijers, A.W.M.; Tsohatzidis, S.L.

    2007-01-01

    From its early development in the 1960s, speech act theory always had an individualistic orientation. It focused exclusively on speech acts performed by individual agents. Paradigmatic examples are ‘I promise that p’, ‘I order that p’, and ‘I declare that p’. There is a single speaker and a single

  3. Americans with Disabilities Act.

    Kaesberg, Mary Ann; Murray, Kenneth T.

    1994-01-01

    Presents a 35-item checklist of practical activities for school district compliance with the Americans with Disabilities Act (ADA). The checklist is based on ADA statutes, other civil rights legislation and litigation, as well as pertinent regulations and the legislative history of the act contained in the Congressional Record. (MLF)

  4. Radiation emitting devices act

    1970-01-01

    This Act, entitled the Radiation Emitting Devices Act, is concerned with the sale and importation of radiation emitting devices. Laws relating to the sale, lease or import, labelling, advertising, packaging, safety standards and inspection of these devices are listed as well as penalties for any person who is convicted of breaking these laws

  5. Nuclear Installations Act 1969

    1969-01-01

    The purpose of this Act is to amend the Nuclear Installations Act 1965 to bring it into full compliance with the international conventions on nuclear third party liability to which the United Kingdom is a Signatory, namely, the Paris Convention, the Brussels Supplementary Convention and the Vienna Convention. (NEA) [fr

  6. 8-OH-DPAT abolishes the pulmonary C-fiber-mediated apneic response to fentanyl largely via acting on 5HT1A receptors in the nucleus tractus solitarius

    Zhuang, Jianguo; Zhang, Zhenxiong; Zhang, Cancan

    2012-01-01

    Intravenous bolus injection of morphine causes a vagal-mediated brief apnea (∼3 s), while continuous injection, via action upon central μ-opioid receptor (MOR), arrests ventilation (>20 s) that is eliminated by stimulating central 5-hydroxytryptamine 1A receptors (5HT1ARs). Bronchopulmonary C-fibers (PCFs) are essential for triggering a brief apnea, and their afferents terminate at the caudomedial region of the nucleus tractus solitarius (mNTS) that densely expresses 5HT1ARs. Thus we asked whether the vagal-mediated apneic response to MOR agonists was PCF dependent, and if so, whether this apnea was abolished by systemic administration of 8-hydroxy-2-(di-n-propylamino)tetral (8-OH-DPAT) largely through action upon mNTS 5HT1ARs. Right atrial bolus injection of fentanyl (5.0 μg/kg, a MOR agonist) was performed in the anesthetized and spontaneously breathing rats before and after: 1) selective blockade of PCFs' conduction and subsequent bivagotomy; 2) intravenous administration of 5HT1AR agonist 8-OH-DPAT; 3) intra-mNTS injection of 8-OH-DPAT; and 4) intra-mNTS injection of 5HT1AR antagonist WAY-100635 followed by 8-OH-DPAT (iv). We found the following: First, fentanyl evoked an immediate apnea (2.5 ± 0.4 s, ∼6-fold longer than the baseline expiratory duration, TE), which was abolished by either blocking PCFs' conduction or bivagotomy. Second, this apnea was prevented by systemic 8-OH-DPAT challenge. Third, intra-mNTS injection of 8-OH-DPAT greatly attenuated the apnea by 64%. Finally, intra-mNTS microinjection of WAY-100635 significantly attenuated (58%) the apneic blockade by 8-OH-DPAT (iv). We conclude that the vagal-mediated apneic response to MOR activation depends on PCFs, which is fully antagonized by systemic 8-OH-DPAT challenge largely via acting on mNTS 5HT1ARs. PMID:22696579

  7. Feeling responsible vs acting responsibly: contributions of a leadership programme

    Karssiens, Astra Elise Amaranta; van der Linden, Claartje; Wilderom, Celeste P.M.

    2013-01-01

    Purpose – The purpose of this paper is to address the effects of a unique leadership programme, four years after its delivery: in a Dutch penitentiary organisation. This intervention was initiated because of a felt lack of safety in an organisation that was characterised by steep hierarchy, forceful

  8. Canada's Clean Air Act

    2006-01-01

    This paper provided an outline of Canada's Clean Air Act and examined some of the regulatory changes that will occur as a result of its implementation. The Act is being introduced to strengthen the legislative basis for taking action on reducing air pollution and GHGs, and will allow the government to regulate both indoor and outdoor air pollutants and GHGs. The Act will require the Ministers of the Environment and Health to establish national air quality objectives, as well as to monitor and report on their attainment. The Canadian Environmental Protection Act will be amended to enable the government to regulate the blending of fuels and their components. The Motor Vehicle Fuel Consumption Standards Act will also be amended to enhance the government's authority to regulate vehicle fuel efficiency. The Energy Efficiency Act will also be expanded to allow the government to set energy efficiency standards and labelling requirements for a wider range of consumer and commercial products. The Act will commit to short, medium and long-term industrial air pollution targets. Regulations will be proposed for emissions from industry; on-road and off-road vehicles and engines; and consumer and commercial products. It was concluded that the Government of Canada will continue to consult with provinces, territories, industries and Canadians to set and reach targets for the reduction of both indoor and outdoor air pollutants and GHG emissions. 6 figs

  9. An Animal Model of Active (Act) Versus Sedentary (Sed) Lifestyle and Susceptibility to Air Pollution: Response to Ozone (O3) in Female Sprague-Dawley Rats Allowed to Train Chronically On Running Wheels

    Epidemiological data suggest that a sedentary lifestyle may contribute to increased suseptibility to environmental pollutants. Furthermore, the association between a sedentary pattern and development of obesity may exacerbate susceptibility. To study the effects of ACT vs. SED l...

  10. The Energy Act 1983

    1983-01-01

    Part II of This Act came into force on 1 September 1983 and is concerned with nuclear installations. Its main purpose is to amend the Nuclear Installations Act 1965 to give effect to the provisions of two Protocols amending the Paris Convention on nuclear third party liability and the Brussels Convention Supplementary to the Paris Convention respectively. The principal effect of these modifications is to increase the sums available to meet claims for nuclear damage. The United Kingdom is a Party to both Conventions and the provisions of the 1983 Act will enable it to ratify the Protocols. (NEA) [fr

  11. Fast-acting valve actuator

    Cho, Nakwon

    1980-01-01

    A fast-acting valve actuator utilizes a spring driven pneumatically loaded piston to drive a valve gate. Rapid exhaust of pressurized gas from the pneumatically loaded side of the piston facilitates an extremely rapid piston stroke. A flexible selector diaphragm opens and closes an exhaust port in response to pressure differentials created by energizing and de-energizing a solenoid which controls the pneumatic input to the actuator as well as selectively providing a venting action to one side of the selector diaphragm.

  12. 75 FR 63703 - Privacy Act of 1974; Privacy Act Regulation

    2010-10-18

    ... FEDERAL RESERVE SYSTEM 12 CFR Part 261a [Docket No. R-1313] Privacy Act of 1974; Privacy Act... implementing the Privacy Act of 1974 (Privacy Act). The primary changes concern the waiver of copying fees... records under the Privacy Act; the amendment of special procedures for the release of medical records to...

  13. Abandoned Shipwreck Act

    National Oceanic and Atmospheric Administration, Department of Commerce — This data represents the extent of the Abandoned Shipwreck Act (ASA). The ASA allows states to manage a broad range of resources within submerged lands, including...

  14. Airway Clearance Techniques (ACTs)

    Full Text Available ... The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy ... the value of tapping into the expertise that only people with CF and their families have. We invite you to share insights to ...

  15. Energy Policy Act

    National Oceanic and Atmospheric Administration, Department of Commerce — The Energy Policy Act (EPA) addresses energy production in the United States, including: (1) energy efficiency; (2) renewable energy; (3) oil and gas; (4) coal; (5)...

  16. Airway Clearance Techniques (ACTs)

    Full Text Available ... There are different ways to clear your airways. Most are easy to do. Infants and toddlers will ... best ACT is the one that you are most likely to perform as part of your daily ...

  17. Airway Clearance Techniques (ACTs)

    Full Text Available ... to loosen mucus from airway walls. See how different airway clearance techniques work to help you clear the thick, sticky mucus ... Offer their tips for fitting ACTs into daily life Airway Clearance Techniques | Webcast ... Facebook Twitter ...

  18. Airway Clearance Techniques (ACTs)

    Full Text Available ... CF Community in Health Care Reform Milestones in Health Care Reform How Tax Reform Could Impact People With CF The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy Achievements ...

  19. Clean Water Act

    National Oceanic and Atmospheric Administration, Department of Commerce — These data represent geographic terms used within the Clean Water Act (CWA). The CWA establishes the basic structure for regulating the addition of pollutants...

  20. Airway Clearance Techniques (ACTs)

    Full Text Available ... toddlers will need help from a parent or caregiver. Older kids and adults can choose ACTs that ... into the smaller airways to attack bacteria. Choose What's Best for You Your respiratory therapist or another ...

  1. Airway Clearance Techniques (ACTs)

    Full Text Available ... that help thin and move the mucus, and antibiotics. Bronchodilators should be inhaled before you start ACTs. This medication helps to widen your airways (bronchi) by relaxing the ...

  2. Endangered Species Act

    National Oceanic and Atmospheric Administration, Department of Commerce — The purpose of the Endangered Species Act (ESA) is to protect and recover imperiled species and the ecosystems upon which they depend. The U.S. Fish and Wildlife...

  3. Airway Clearance Techniques (ACTs)

    Full Text Available ... Reform Could Impact People With CF The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy Achievements ... on their own. Share Facebook Twitter Email More options Print Share Facebook Twitter Email Print Permalink All ...

  4. Airway Clearance Techniques (ACTs)

    Full Text Available ... 3-D Structure Consortium CFTR Folding Consortium Epithelial Stem Cell Consortium Mucociliary Clearance Consortium SUCCESS WITH THERAPIES RESEARCH ... ACTs involve coughing or huffing . Many of them use percussion (clapping) or vibration to loosen mucus from ...

  5. Airway Clearance Techniques (ACTs)

    Full Text Available ... today. ANNUAL FUND Become a Corporate Supporter Cause Marketing Make a Charitable Gift Our Corporate Supporters Workplace ... Clearance Airway Clearance Techniques (ACTs) There are different ways to clear your airways. Most are easy to ...

  6. Marine Pollution Prevention Act

    National Oceanic and Atmospheric Administration, Department of Commerce — The Marine Pollution Prevention Act of 2008 implements the International Convention for the Prevention of Pollution from Ships, including related Protocols (MARPOL)...

  7. Airway Clearance Techniques (ACTs)

    Full Text Available ... CF Community in Health Care Reform Milestones in Health Care Reform How Tax Reform Could Impact People With CF The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy Achievements Advocacy News Briefings, Testimonies, and Regulatory ...

  8. Preventive Radiation Protection Act

    Roewer, H.

    1988-01-01

    The commentary is intended to contribute to protection of the population by a practice-oriented discussion and explanation of questions arising in connection with the Preventive Radiation Protection Act. Leaving aside discussions about abandonment of nuclear power, or criticism from any legal point of view, the commentary adopts the practical approach that accepts, and tries to help implementing, the act as it is. It is a guide for readers who are not experts in the law and gives a line of orientation by means of explanations and sometimes by citations from other acts (in footnotes). The commentary also presents the EURATOM Directive No. 3954/87 dated 22 December 1987, the EC Directive No. 3955/87 dated 22 December 1987, and the EC Directive No. 1983/88 dated 5 July 1988. A tabular survey shows the system of duties and competences defined by the Preventive Radiation Protection Act. (RST) [de

  9. Airway Clearance Techniques (ACTs)

    Full Text Available ... Contraception and Protection How Does CF Affect the Female Reproductive System? How Does CF Affect the Male ... Reform Could Impact People With CF The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy Achievements ...

  10. ACT250 Districts

    Vermont Center for Geographic Information — The ACT 250 Districts layer is part of a larger dataset that contains administrative boundaries for Vermont's Agency of Natural Resources. The dataset includes...

  11. Airway Clearance Techniques (ACTs)

    Full Text Available ... ACTs involve coughing or huffing . Many of them use percussion (clapping) or vibration to loosen mucus from airway walls. See how different airway clearance techniques work to help you clear the thick, sticky mucus ...

  12. Acts of Research

    Nelund, Sidsel

    place mostly in seminars and articles, in which knowledge is often discussed as an intrinsic quality of the artwork. Acts of Research, however, is devoted to studying the rise of knowledge production in contemporary art from the perspective of artistic, curatorial and educational research...... described as knowledge producers and exhibitions and art works as instances of knowledge production. Acts of Research: Knowledge Production in Contemporary Arts between Knowledge Economy and Critical Practices analyses this development. The academic discussion of knowledge production in the arts has taken...... with an awareness of larger political, economic, geographical and art-related aspects. The concept of ‘acts of research’ is suggested as a way to understand knowledge production as a creative act in which research carried out in relation to a specific material challenges and resists the protocols of conventional...

  13. Airway Clearance Techniques (ACTs)

    Full Text Available ... Congressional Cystic Fibrosis Caucus Our Policy Agenda Policy Principles SIGN UP FOR ADVOCACY ACTION ALERTS Community We ... options Print Share Facebook Twitter Email Print Permalink All ACTs involve coughing or huffing . Many of them ...

  14. Airway Clearance Techniques (ACTs)

    Full Text Available ... How Does CF Affect the Male Reproductive System? Sex and CF: Some Practical Advice Family Planning and ... need help from a parent or caregiver. Older kids and adults can choose ACTs that they can ...

  15. Airway Clearance Techniques (ACTs)

    Full Text Available ... FOR ADVOCACY ACTION ALERTS Community We recognize the value of tapping into the expertise that only people ... ACTs involve coughing or huffing . Many of them use percussion (clapping) or vibration to loosen mucus from ...

  16. National Environmental Policy Act

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Environmental Policy Act (NEPA) was the first major environmental law in the United States and established national environmental policies for the...

  17. Airway Clearance Techniques (ACTs)

    Full Text Available ... Reform Could Impact People With CF The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy Achievements ... Board of Trustees Our Leadership Careers Reports and Financials Contact Us Governance and Policies What is CF? ...

  18. Airway Clearance Techniques (ACTs)

    Full Text Available ... own. Share Facebook Twitter Email More options Print Share Facebook Twitter Email Print Permalink All ACTs involve ... CF Care Team Research About Our Research Developing New Treatments Researcher Resources Assistance Services Find Resources: CF ...

  19. Affordable Care Act (ACA)

    Social Security Administration — The Affordable Care Act (ACA) is a federal statute enacted with a goal of increasing the quality and affordability of health insurance. Through a web service, CMS...

  20. Airway Clearance Techniques (ACTs)

    Full Text Available ... The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy Achievements Advocacy News Briefings, Testimonies, and Regulatory Comments Congressional Cystic Fibrosis Caucus Our Policy Agenda Policy Principles SIGN UP FOR ADVOCACY ACTION ...

  1. Airway Clearance Techniques (ACTs)

    Full Text Available ... people with cystic fibrosis so that they make smart decisions about CF-related research, treatment, and access ... The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy Achievements Advocacy News Briefings, Testimonies, and Regulatory ...

  2. Airway Clearance Techniques (ACTs)

    Full Text Available ... What to Consider Regarding a Lung Transplant Medications Antibiotics Bronchodilators CFTR Modulator Therapies Mucus Thinners Nebulizer Care ... that help thin and move the mucus, and antibiotics. Bronchodilators should be inhaled before you start ACTs. ...

  3. Airway Clearance Techniques (ACTs)

    Full Text Available ... resources you need to continuously build upon this work. Awards and Grants Career Development Awards Research Awards ... The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy Achievements Advocacy News Briefings, Testimonies, and Regulatory ...

  4. The Corporations Act 2001

    Bostock, Tom

    2002-01-01

    The author outlines reforms made in Australia in the area of company law with an analysis of the Corporations Act 2001, which along with the Australian Securities and Investments Commission Act 2001 comprises Corporations legislation in Australia. Article by Tom Bostock (a partner in the law firm Mallesons Stephen Jaques, Melbourne, Australia). Published in Amicus Curiae - Journal of the Institute of Advanced Legal Studies and its Society for Advanced Legal Studies. The Journal is produced by...

  5. Outer Continental Shelf Lands Act

    National Oceanic and Atmospheric Administration, Department of Commerce — This data represents geographic terms used within the Outer Continental Shelf Lands Act (OCSLA or Act). The Act defines the United States outer continental shelf...

  6. Atomic Energy Act 1953-1966

    1970-01-01

    The Atomic Energy Act 1953-1966 establishes the Australian Atomic Energy Commission and lays down its powers, duties, rules of procedure and financing. The members of the Commission are appointed by the Governor-General. It is responsible, inter alia, for all activities covering uranium research, mining and trading as well as for atomic energy development and nuclear plant construction and operation. Its duties also include training of scientific research workers and collection and dissemination of information on atomic energy. For purposes of security, the Act further-more prescribes sanctions in relation to unauthorised acquisition or communication of information on this subject. Finally, the Act repeals the Atomic Energy (Control of Materials) Act 1946 and 1952. (NEA) [fr

  7. Technology and responsibility

    Zimmerli, W.C.

    1987-01-01

    Philosophical reflections on the concepts of responsibility and type of responsibility are presented and discussed with regard to the developments of technology. The author states that neither the relationship between liability and responsibility has changed, nor the structure of responsibility. Any individual still is responsible for his actions and their consequences. What has changed, however, is the former restriction to the concept of internal responsibility and the overlapping of acting subject and responsible subject. (DG) [de

  8. The Clean Air Act

    Coburn, L.L.

    1990-01-01

    The Clean Air Act amendments alter the complex laws affecting atmospheric pollution and at the same time have broad implications for energy. Specifically, the Clean Air Act amendments for the first time deal with the environmental problem of acid deposition in a way that minimizes energy and economic impacts. By relying upon a market-based system of emission trading, a least cost solution will be used to reduce sulfur dioxide (SO 2 ) emissions by almost 40 percent. The emission trading system is the centerpiece of the Clean Air Act (CAA) amendments effort to resolve energy and environmental interactions in a manner that will maximize environmental solutions while minimizing energy impacts. This paper will explore how the present CAA amendments deal with the emission trading system and the likely impact of the emission trading system and the CAA amendments upon the electric power industry

  9. Medicaid/CHIP Program; Medicaid Program and Children's Health Insurance Program (CHIP); Changes to the Medicaid Eligibility Quality Control and Payment Error Rate Measurement Programs in Response to the Affordable Care Act. Final rule.

    2017-07-05

    This final rule updates the Medicaid Eligibility Quality Control (MEQC) and Payment Error Rate Measurement (PERM) programs based on the changes to Medicaid and the Children's Health Insurance Program (CHIP) eligibility under the Patient Protection and Affordable Care Act. This rule also implements various other improvements to the PERM program.

  10. ST–ACTS

    Gidofalvi, Gyozo; Pedersen, Torben Bach

    2006-01-01

    hot issue in the area of spatio–temporal databases [7]. While existing Moving Object Simulators (MOSs) address different physical aspects of mobility, they neglect the important social and geo–demographical aspects of it. This paper presents ST–ACTS, a Spatio–Temporal ACTivity Simulator that, using...... various geo–statistical data sources and intuitive principles, models the so far neglected aspects. ST–ACTS considers that (1) objects (representing mobile users) move from one spatio–temporal location to another with the objective of performing a certain activity at the latter location; (2) not all users...

  11. Atomic Energy Act 1989

    1989-05-01

    This Act, which entered into force on 1 september 1989, contains a series of provisions dealing with different subjects: increase of public financing for British Nuclear Fuels plc, amendment of the Nuclear Installations Act 1965 regarding the powers of the Health and Safety Executive to recover expenses directly from nuclear operators and obligation of the UKAEA to take out insurance or other financial security to cover its liability and finally, measures to enable the UK to ratify the IAEA Convention on Assistance in Case of a Nuclear Accident or Radiological Emergency [fr

  12. Airway Clearance Techniques (ACTs)

    Full Text Available ... NACFC Carolyn and C Richard Mattingly Leadership in Mental Health Care Award Mary M. Kontos Award NACFC Reflections ... CF Community in Health Care Reform Milestones in Health Care Reform How Tax Reform Could ... Act Our Advocacy Work Advocacy Achievements ...

  13. Airway Clearance Techniques (ACTs)

    Full Text Available ... Team Your cystic fibrosis care team includes a group of CF health care professionals who partner with ... Awards and Grants Career Development Awards Research Awards Training Awards CF ... Clearance Airway Clearance Techniques (ACTs) There are different ways to clear your ...

  14. "Act in Good Faith."

    McKay, Robert B.

    1979-01-01

    It is argued that the Supreme Court's Bakke decision overturning the University of California's minority admissions program is good for those who favor affirmative action programs in higher education. The Supreme Court gives wide latitude for devising programs that take race and ethnic background into account if colleges are acting in good faith.…

  15. Special Appropriation Act Projects

    EPA is sometimes directed to provide funding to a specific entity for study, purpose, or activity.This information will be of interest to a community or other entity that has been identified in one of EPA's appropriations acts to receive such funding.

  16. Radioactive Substances Act 1948

    1948-01-01

    This Act regulates the use of radioactive substances and radiation producing devices in the United Kingdom. It provides for the control of import, export, sale, supply etc. of such substances and devices and lays down the safety regulations to be complied with when dealing with them. (NEA) [fr

  17. Airway Clearance Techniques (ACTs)

    Full Text Available ... Reform Could Impact People With CF The Preserving Employee Wellness Programs Act Our Advocacy Work Advocacy Achievements ... AWARENESS Tomorrow’s Leaders About Us News Blog Chapters Facebook Twitter YouTube Instagram Email DONATE Breadcrumb Navigation Home ...

  18. Airway Clearance Techniques (ACTs)

    Full Text Available ... Practical Advice Family Planning and Parenting With CF Making Your Family Planning Decisions Pregnancy and CF Alternative Ways to Build a ... with cystic fibrosis so that they make smart decisions about CF-related research, treatment, and access to care. ... Act Our Advocacy Work Advocacy Achievements ...

  19. Airway Clearance Techniques (ACTs)

    Full Text Available ... programs and policies to improve the lives of people with CF. Help us by raising awareness of CF, participating in a fundraising event, or volunteering ... clear your airways. Most are easy to do. Infants and toddlers will need help from a parent or caregiver. Older kids and adults can choose ACTs that they ...

  20. Airway Clearance Techniques (ACTs)

    Full Text Available ... and Their Families When There's More Than One Person With CF in the Same School Daily Life ... Awards and Grants Career Development Awards Research Awards Training Awards CF ... Clearance Airway Clearance Techniques (ACTs) There are different ways to clear your ...

  1. Ocean Dumping Control Act

    1975-01-01

    This Act provides for the control of dumping of wastes and other substances in the ocean in accordance with the London Convention of 1972 on Prevention of Marine Pollution by the Dumping of Wastes and other Matter to which Canada is a Party. Radioactive wastes are included in the prohibited and restricted substances. (NEA)

  2. Airway Clearance Techniques (ACTs)

    Full Text Available ... to try. However, the best ACT is the one that you are most likely to perform as part of your daily treatment plan. Watch the webcast below to hear a respiratory therapist, a child with CF and her father: Demonstrate and discuss ...

  3. The Child Justice Act

    Stephan

    1995-06-16

    Jun 16, 1995 ... Gallinetti "Child Justice" 648; Le Roux-Kemp 2008 Annual Survey of South African Law 298 (the. Act contains a "separate, but parallel, ... The various aspects of section 68 are then evaluated. The greatest challenges lie in the ... See also, eg, Picardi Hotels v Thekwini. Properties 2009 1 SA 493 (SCA) para ...

  4. Airway Clearance Techniques (ACTs)

    Full Text Available ... Data Requests Get Involved X close Advocate Our goal is to educate policy makers about the needs ... Reform Could Impact People With CF The Preserving Employee Wellness Programs Act Our Advocacy ... Assistance Services Find Resources: CF Foundation Compass Insurance Get ...

  5. Airway Clearance Techniques (ACTs)

    Full Text Available ... Offer their tips for fitting ACTs into daily life Airway Clearance Techniques | Webcast To learn more about how you can help your infant or child manage their lung health, watch parents of children with CF and a respiratory therapist ...

  6. Act local, think global

    Lewis, Chris; McRoberts, Doug

    2002-01-01

    Tip O'Neill, one of the grand old men of modem US politics, once famously remarked that all politics is local. Like most politicians who succeed on the national stage - and not just in the US - it was a truth he never lost sight of. What is true for politicians is equally true in the communications business. We may increasingly live in a global village, but successful companies - even multi-nationals - forget the importance of local and regional public relations at their peril. Think of Douglas Ivester, the CEO of Coca-Cola at the time of the 1999 Belgian contamination scandal, who allegedly reacted to first reports of the crisis by asking: 'Where the hell is Belgium?' A more appropriate question today - several years after Coke's share price toppled and the CEO was unceremoniously sacked - might be: 'Who the hell is Douglas Nester?' But - to adapt another famous phrase - the fact that communications (and marketing) professionals still need to 'act local' as much as ever before should not blind us to the growing need to 'think global'. In the nuclear industry, as in the world economy generally, increasing global integration is a reality, as are the international nature of the news media and the increasingly global nature of the anti-nuclear pressure groups. Indeed, it was the growing need for a truly global information network to counter these trends, by increasing the overall speed and accuracy of the worldwide nuclear information flow, that led the nuclear community to establish NucNet in 1991. So where exactly is the line between local and regional nuclear communications on the one hand, and global communications on the other? Is there one spin for a regional audience, and another for a global audience? This presentation proposes some guiding principles, by examining the response of nuclear communicators world-wide to the new communications agenda imposed in the wake of the September 11th suicide attacks in the US. NucNet President Doug McRoberts and Executive

  7. Slovak Republic Act of 11 February 1998 on the energetics and on alterations to Act No. 455/1991 Collection of Acts of CSFR on small business (trade Act) in version of posterior regulations

    1998-01-01

    This act constitute: (a) conditions of undertaking in electro-energetic, gas industry, and heat supply (in next only 'energetic' branches) ; (b) rights and responsibility of physical and act person undertaking in energetic branches; (c) rights and responsibility of customers of electricity, gas, and heat; counteract measures in the need situations, (d) and at prevention before need situations in energetic branches; (e) state regulation in energetic; (f) authority on keep of this act. The act is divided into for parts: (1) General constitutions, (2) Energetic branches; (3) The state authority; (4) Common, transient and invalidation constitutions.This act deals with the specific conditions for undertaking in nuclear power plants, too (licensing, security). This act shall into effect on 1 July 1998

  8. Dreams and acting out.

    Grinberg, L

    1987-01-01

    Dreams can be used as containers that free patients from increased tension. This may be the principal function of certain types of dreams, called "evacuative dreams." They are dreams used for getting rid of unbearable affects and unconscious fantasies, or as a safety valve for partial discharge of instinctual drives. These dreams are observed primarily in borderline and psychotic patients, but can also be seen in the regressive states of neurotic patients during weekends and other periods of separation. Such dreams have to be differentiated from "elaborative dreams," which have a working-through function and stand in an inverse relationship to acting out: the greater the production of elaborative dreams, the less the tendency to act out, and vice versa.

  9. Atomic Energy Act 1946

    1946-01-01

    This Act provides for the development of atomic energy in the United Kingdom and for its control. It details the duties and powers of the competent Minister, in particular his powers to obtain information on and to inspect materials, plant and processes, to control production and use of atomic energy and publication of information thereon. Also specified is the power to search for and work minerals and to acquire property. (NEA) [fr

  10. Radiological protection act, 1991

    1991-01-01

    This Act provides for the establishment of the Radiological Protection Institute of Ireland and dissolves An Bord Fuinnimh Nuicleigh (the Board), transferring its assets and liabilities to the Institute. It sets out a range of radiation protection measures to be taken by various Ministers in the event of a radiological emergency and gives effect at national level to the Assistance Convention, the Early Notification Convention and the Physical Protection Convention. The Institute is the competent Irish authority for the three Conventions. (NEA) [fr

  11. Toxic Substances Control Act

    1992-05-15

    This Reference Book contains a current copy of the Toxic Substances Control Act and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (202/586-2609).

  12. 78 FR 57402 - Privacy Act of 1974; Department of Homeland Security/U.S. Customs and Border Protection-019 Air...

    2013-09-18

    ..., 1225, and 1324; and the Immigration Reform and Immigrant Responsibility Act of 1996, Public Law 104-208..., 1225, and 1324; the Illegal Immigration Reform and Immigrant Responsibility Act of 1996, Public Law 104... [[Page 57405

  13. SALMON AND THE ENDANGERED SPECIES ACT: TROUBLESOME QUESTIONS

    Throughout the Pacific Northwest and California, all wild salmon runs have declined since 1850 and some have disappeared. A sustainable future for wild salmon remains elusive. In response to requirements of the U.S. Endangered Species Act, the Canadian Species at Risk Act, and ...

  14. Williamson Act - The California Land Conservation Act of 1965

    California Natural Resource Agency — The California Land Conservation Act of 1965 - commonly referred to as the Williamson Act - is the State's primary program for the conservation of private land in...

  15. Radioactive Ores and Concentrates (Packaging and Transport) Act 1980. No 26 of 1980

    1980-01-01

    This Act, which regulates the packaging, storage and transport of radioactive ores and concentrates lays down a detailed licensing system for such materials and prescribes the duties of the Chief Inspector responsible for implementation of the Act. (NEA) [fr

  16. Act to amend cost regulations of the Atomic Energy Act

    1980-01-01

    Article 21 is replaced by articles 21 to 21b. According to this, fees or reimbursements for expenses for official acts (e.g. decisions, supervisory acts, safeguarding of nuclear fuels) as well as for the use of facilities according to article 9a, section 3, of the Atomic Energy Act (e.g. Laender facilities to collect nuclear waste). (HP) [de

  17. Teaching Speech Acts

    Teaching Speech Acts

    2007-01-01

    Full Text Available In this paper I argue that pragmatic ability must become part of what we teach in the classroom if we are to realize the goals of communicative competence for our students. I review the research on pragmatics, especially those articles that point to the effectiveness of teaching pragmatics in an explicit manner, and those that posit methods for teaching. I also note two areas of scholarship that address classroom needs—the use of authentic data and appropriate assessment tools. The essay concludes with a summary of my own experience teaching speech acts in an advanced-level Portuguese class.

  18. The Experiment as Act

    Søndergaard, Morten

    In December 1965, an experiment took place at The Independent Art Space in Copenhagen (Den Frie Kunstbygning). Short named POEX65, it was looking to create and activate POetry EXperiments across artistic genres and formats (thus, in essence, making a POetry EXposition). The POEX65 event framed many...... to be able to analyse the phenomena found at POEX65. Here I will use the notion of the ‘ontological theatre’ (Pickering), which, according to Pickering, is acted out in experimental art productions. The experiment could thus be seen as an ‘agency-realism’ – as an ‘act’ of relations across the aesthetics...

  19. Atomic Energy Authority Act 1954

    1954-01-01

    This Act provides for the setting up of an Atomic Energy Authority for the United Kingdom. It also makes provision for the Authority's composition, powers, duties, rights and liabilities, and may amend, as a consequence of the establishment of the Authority and in connection therewith, the Atomic Energy Act, 1946, the Radioactive Substances Act 1948 and other relevant enactments. (NEA) [fr

  20. 76 FR 59073 - Privacy Act

    2011-09-23

    ... CENTRAL INTELLIGENCE AGENCY 32 CFR Part 1901 Privacy Act AGENCY: Central Intelligence Agency. ACTION: Proposed rule. SUMMARY: Consistent with the Privacy Act (PA), the Central Intelligence Agency...-1379. SUPPLEMENTARY INFORMATION: Consistent with the Privacy Act (PA), the CIA has undertaken and...

  1. Equality Act 2010: knowledge, perceptions and practices of occupational physicians.

    Masupe, T; Parker, G

    2013-04-01

    Historically, many prospective employees in Great Britain have undergone pre-employment health screening (PEHS) assessments before a job offer. Section 60 of the Equality Act 2010 stipulates that PEHS assessments before a job offer may contravene the disability provisions of the Act except under specific circumstances. PEHS assessments in the current format may not fully comply with the provisions of the legislation. To describe the knowledge, perceptions and practices of occupational health physicians in UK following implementation of the Equality Act 2010. Data were collected through an anonymous online survey of occupational health physicians (OHPs) actively reporting to the Occupational Physicians Reporting Activity (OPRA) at the Centre for Occupational and Environmental Health, the University of Manchester. There were 126 responses available for analysis (response rate 43%). Most participants (81%) were accredited occupational health specialists providing occupational health advice to various industry sectors; 96% reported involvement in PEHS assessments; 81% reported awareness of section 60 of the Equality Act 2010. Further analysis of these participants revealed varying knowledge levels and practices relating to specific requirements of section 60. Changes in professional practice resulting from the Act were reported by 38%, while 46% reported no change. There have been minimal immediate changes to PEHS practices by OHPs in response to section 60 of the Act. Some OHPs displayed inadequate knowledge of specific requirements of section 60 of the Act. OHPs could benefit from further training on specific requirements of this legislation.

  2. Acting to gain information

    Rosenchein, Stanley J.; Burns, J. Brian; Chapman, David; Kaelbling, Leslie P.; Kahn, Philip; Nishihara, H. Keith; Turk, Matthew

    1993-01-01

    This report is concerned with agents that act to gain information. In previous work, we developed agent models combining qualitative modeling with real-time control. That work, however, focused primarily on actions that affect physical states of the environment. The current study extends that work by explicitly considering problems of active information-gathering and by exploring specialized aspects of information-gathering in computational perception, learning, and language. In our theoretical investigations, we analyzed agents into their perceptual and action components and identified these with elements of a state-machine model of control. The mathematical properties of each was developed in isolation and interactions were then studied. We considered the complexity dimension and the uncertainty dimension and related these to intelligent-agent design issues. We also explored active information gathering in visual processing. Working within the active vision paradigm, we developed a concept of 'minimal meaningful measurements' suitable for demand-driven vision. We then developed and tested an architecture for ongoing recognition and interpretation of visual information. In the area of information gathering through learning, we explored techniques for coping with combinatorial complexity. We also explored information gathering through explicit linguistic action by considering the nature of conversational rules, coordination, and situated communication behavior.

  3. The new Swiss Energy Act

    Tami, R.

    1999-01-01

    The new Swiss Energy Act and the accompanying regulation enable the instructions given in the poll by the electorate in 1990 -- the Energy Article in the Swiss Constitution -- to be implemented. The Energy Act creates the necessary basis for an advanced and sustainable energy policy. It should contribute to a sufficient, broadly based, dependable, economical and environment-friendly energy supply. The Energy Act and the Energy Regulation entered into force on January 1, 1999. (author)

  4. Act No. 1240 of 15 December 1971. Regulations concerning the restructuring of the National Nuclear Energy Commission (CNEN)

    1972-01-01

    This Act which annuls the preceding Act of 1960 with the exception of Sections 12 to 16, confirms the CNEN's responsibilities. As opposed to the previous Act this Act contains provisions concerning the National Institute for Nuclear Physics (INFN). (NEA) [fr

  5. Atomic Energy Authority Act 1971

    1971-01-01

    This Act provides for the transfer of property, rights, liabilities and obligations of parts of the undertaking of the United Kingdom Atomic Energy Autority, to two new Compagnies set up for this purpose: the Bristish Nuclear Fuels Limited, and the Radiochemical Centre Limited. Patents licences and registered designs owned by the Autority at the time of the transfer are not included therein. The Act also includes amendments to the Nuclear Installations Act 1965, notably as regards permits to operate granted to a body corporate. Finally, the Schedule to this Act lays down a certain number of provisions relating to security and the preservation of secrets. (NEA) [fr

  6. Six Acts of Miscognition: Implications for Art Education

    Tavin, Kevin M.

    2010-01-01

    Employing Lacanian theory as a necessary supplement to contemporary approaches in art education, this article provides a critique and response to art education discourse around "cognition." This response unfolds in six acts: (1) Unknown knowledge, (2) Unmeant knowledge, (3) Missing metaphors, (4) Stupidity, (5) Symptoms and sinthomes, and (6)…

  7. An Act to regulate the keeping and use of radioactive substances, irradiating apparatus and certain electronic products, and for matters incidental thereto (No. 440 of 1975)

    1975-01-01

    This Radiation Safety Act 1975 which applies to radioactive substances and irradiating apparatus is a framework Act governing activities involving their possession and applications including their disposal. It makes provision for the duties and powers of the authorities responsible for administering the Act (the Radiological Council), licensing requirements and exemptions therefrom, registration of such substances and apparatus, inspection procedures and liability under the Act. The Radioactive Substances Act 1954, the Radioactive Substances Act Amendment Acts 1960 and 1964 are repealed. (NEA) [fr

  8. Complying with the Federal Facilities Compliance Act

    Pavetto, C.S.; Watmore, A.S.

    1994-01-01

    The Federal Facilities Compliance Act (FFCA), signed into law on October 6, 1992, amended the Resource Conservation and Recovery Act (RCRA) to place significant additional environmental compliance responsibilities on federal facilities. The federal government has expressly waived sovereign immunity regarding hazardous waste enforcement action taken against these facilities by the states and the EPA. An exception exists for mixed waste violations. The FFCA defines mixed waste as hazardous waste, as defined by RCRA, combined with source, special nuclear or by-product material that is subject to the Atomic Energy Act of 1954. As the majority owner of mixed waste in the United States, the Department of Energy (DOE) must satisfy several new requirements under the FFCA for their facilities. This paper reviews the FFCA's requirements and how they apply to and may affect the DOE and other federal facilities. Included in the review are responsibilities of federal agencies involved and the role of the EPA and the states. In addition, this paper discusses the intent of the FFCA to encourage development of federal facility agreements (FFA) between federal agencies, the EPA and state environmental regulatory agencies

  9. Appendix: The Dream Act of 2009--111th Congress, 1st Session, S.729

    New Directions for Student Services, 2010

    2010-01-01

    This article describes the Development, Relief, and Educational for Alien Minors Act of 2009 or the "DREAM Act of 2009." The authors of the bill aim to amend the Illegal Immigration Reform and Immigrant Responsibility Act of 1996 to permit States to determine State residency for higher education purposes and to authorize the cancellation…

  10. [Euthanasia and medical act].

    2011-05-01

    Right to life -as the prohibition of intentionally and arbitrarily taking life, even with authorization of the concerned one- is an internationally recognized right. In many countries, debate regarding euthanasia is more centered in its convenience, social acceptability and how it is regulated, than in its substantial legitimacy. Some argue that euthanasia should be included as part of clinical practice of health professionals, grounded on individual's autonomy claims-everyone having the liberty to choose how to live and how to die. Against this, others sustain that life has a higher value than autonomy, exercising autonomy without respecting the right to life would become a serious moral and social problem. Likewise, euthanasia supporters some-times claim a 'right to live with dignity', which must be understood as a personal obligation, referred more to the ethical than to the strictly legal sphere. In countries where it is already legalized, euthanasia practice has extended to cases where it is not the patient who requests this but the family or some healthcare professional, or even the legal system-when they think that the patient is living in a condition which is not worthy to live. Generalization of euthanasia possibly will end in affecting those who need more care, such as elder, chronically ill or dying people, damaging severely personal basic rights. Nature, purpose and tradition of medicine rule out the practice of euthanasia, which ought not be considered a medical act or legitimately compulsory for physicians. Today's medicine counts with effective treatments for pain and suffering, such as palliative care, including sedative therapy, which best preserves persons dignity and keeps safe the ethos of the medical profession.

  11. Corporate responsibility

    Jensen, Karsten Klint

    2007-01-01

    Is it legitimate for a business to concentrate on profits under respect for the law and ethical custom? On the one hand, there seems to be good reasons for claiming that a corporation has a duty to act for the benefit of all its stakeholders. On the other hand, this seems to dissolve the notion...... of a private business; but then again, a private business would appear to be exempted from ethical responsibility. This is what Kenneth Goodpaster has called the stakeholder paradox: either we have ethics without business or we have business without ethics. Through a different route, I reach the same solution...

  12. Healh and Safety at Work etc. Act 1974

    1974-01-01

    The main purpose of this Act is to provide a single comprehensive and integrated system of law dealing with the health, safety and welfare of workpeople, and the health and safety of the public as affected by work activities. The Act establishes a Health and Safety Commission and a Health and Safety Executive to be generally responsible for administering health and safety legislation, including those provisions of the Nuclear Installations Act 1965 governing the licensing of nuclear installations, a function which was exercised by the Secretary of State for Energy and the Secretary of State for Scotland. The provisions of the Nuclear Installations Act 1965 and 1969 which give effect to the Paris Convention and the Brussels Supplementary Convention are not affected by the Act. (NEA) [fr

  13. 7 CFR 65.100 - Act.

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Act. 65.100 Section 65.100 Agriculture Regulations of... MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) COUNTRY OF ORIGIN LABELING OF BEEF..., AND GINSENG General Provisions Definitions § 65.100 Act. Act means the Agricultural Marketing Act of...

  14. Nuclear Material (Offences) Act 1983

    1983-01-01

    The main purpose of this Act is to enable the United Kingdom to ratify the Convention on the Physical Protection of Nuclear Material which opened for signature at Vienne and New York on 3 March 1980. The Act extends throughout the United Kingdom. (NEA) [fr

  15. Nurse Reinvestment Act. Public Law.

    Congress of the U.S., Washington, DC.

    This document contains the text of the Nurse Reinvestment Act, which amends the Public Health Service Act to address the increasing shortage of registered nurses by instituting a series of policies to improve nurse recruitment and nurse retention. Title I details two initiatives to boost recruitment of nurses. The first initiative includes the…

  16. Nuclear industry (Finance) Act 1981

    1981-01-01

    The purpose of the Act is to enable British Nuclear Fuels Limited to make borrowings backed by Government guarantees in order to finance its ten year investment programme. More specifically, the Act raises the financial limit applicable to British Nuclear Fuels Limited from pound 500 million to pound 1,000 million. (NEA) [fr

  17. 78 FR 46256 - Privacy Act

    2013-07-31

    ... FEDERAL ELECTION COMMISSION 11 CFR Part 1 Privacy Act CFR Correction In Title 11 of the Code of Federal Regulations, revised as of January 1, 2012, on page 5, in Sec. 1.2, the words ``95 and 96 of the Internal Revenue Code of 1954.'' are added at the end of the definition of Act. [FR Doc. 2013-18535 Filed 7...

  18. Radiation Protection and Control Act 1982. No 49 of 1982

    1982-01-01

    This Act provides for radiation protection in the State of South Australia. It controls activities related to radioactive substances and irradiating apparatus and lays down a licensing system to this effect. The South Australia Health Commission is responsible for administering the Act and is advised by the Radiation Protection Committee created for this purpose. The powers and duties of both bodies are set out in detail. (NEA) [fr

  19. Novel galeterone analogs act independently of AR and AR-V7 for the activation of the unfolded protein response and induction of apoptosis in the CWR22Rv1 prostate cancer cell model.

    McCarty, David J; Huang, Weiliang; Kane, Maureen A; Purushottamachar, Puranik; Gediya, Lalji K; Njar, Vincent C O

    2017-10-24

    The androgen receptor (AR) has long been the primary target for the treatment of prostate cancer (PC). Despite continuous efforts to block AR activity through ligand depletion, AR antagonism, AR depletion and combinations thereof, advanced PC tumors remain resilient. Herein, we evaluate two galeterone analogs, VNPT-178 and VNLG-74A, in PC cell models of diverse androgen and AR dependence attempting to delineate their mechanisms of action and potential clinical utility. Employing basic biochemical techniques, we determined that both analogs have improved antiproliferative and anti-AR activities compared to FDA-approved abiraterone and enzalutamide. However, induction of apoptosis in these models is independent of the AR and its truncated variant, AR-V7, and instead likely results from sustained endoplasmic reticulum stress and deregulated calcium homeostasis. Using in silico molecular docking, we predict VNPT-178 and VNLG-74A bind the ATPase domain of BiP/Grp78 and Hsp70-1A with greater affinity than the AR. Disruption of 70 kDa heat shock protein function may be the underlying mechanism of action for these galeterone analogs. Therefore, despite simultaneously antagonizing AR activity, AR and/or AR-V7 expression alone may inadequately predict a patient's response to treatment with VNPT-178 or VNLG-74A. Future studies evaluating the context-specific limitations of these compounds may provide clarity for their clinical application.

  20. Legislation in Hungary. Implementation of the Act on Atomic Energy

    Szonyi, Z.

    1999-01-01

    The presentation gives a short overview of the history and development of the Hungarian nuclear regulatory regime. The new Act on Atomic Energy is a consequence of the significant internal and international changes. The main characteristic of the Act represent the new expectations and challenges of the nuclear community and the solid and reliable Hungarian legal solutions. The competences, duties and responsibilities of Hungarian Atomic Energy Authority and of the joining other relevant ministries and the complete regulatory framework guarantee the enforcement of the requirements set by the Act.(author)

  1. 76 FR 9034 - Privacy Act of 1974; Department of Homeland Security United States Citizenship and Immigration...

    2011-02-16

    ... Immigrant Responsibility Act of 1996 (IIRIRA), Public Law (Pub. L.) 104-208, September 30, 1996. The E... Immigration Reform and Immigrant Responsibility Act of 1996 (IIRIRA), Public Law 104-208, dated September 30... system: Storage: Records in this system are stored electronically, on magnetic disc, tape, digital media...

  2. 78 FR 8963 - Update of Existing Privacy Act-NASA Regulations

    2013-02-07

    ... FR 60622] inadvertently omits the responsibility of NASA's Freedom of Information Act (FOIA) Office..., this correction adds responsibility of the FOIA Office. This corrections also corrects the title to Sec... appropriate system manager, or, if unknown, to the Center Privacy Manager or Freedom of Information Act (FOIA...

  3. The MIntAct project—IntAct as a common curation platform for 11 molecular interaction databases

    Orchard, Sandra; Ammari, Mais; Aranda, Bruno; Breuza, Lionel; Briganti, Leonardo; Broackes-Carter, Fiona; Campbell, Nancy H.; Chavali, Gayatri; Chen, Carol; del-Toro, Noemi; Duesbury, Margaret; Dumousseau, Marine; Galeota, Eugenia; Hinz, Ursula; Iannuccelli, Marta; Jagannathan, Sruthi; Jimenez, Rafael; Khadake, Jyoti; Lagreid, Astrid; Licata, Luana; Lovering, Ruth C.; Meldal, Birgit; Melidoni, Anna N.; Milagros, Mila; Peluso, Daniele; Perfetto, Livia; Porras, Pablo; Raghunath, Arathi; Ricard-Blum, Sylvie; Roechert, Bernd; Stutz, Andre; Tognolli, Michael; van Roey, Kim; Cesareni, Gianni; Hermjakob, Henning

    2014-01-01

    IntAct (freely available at http://www.ebi.ac.uk/intact) is an open-source, open data molecular interaction database populated by data either curated from the literature or from direct data depositions. IntAct has developed a sophisticated web-based curation tool, capable of supporting both IMEx- and MIMIx-level curation. This tool is now utilized by multiple additional curation teams, all of whom annotate data directly into the IntAct database. Members of the IntAct team supply appropriate levels of training, perform quality control on entries and take responsibility for long-term data maintenance. Recently, the MINT and IntAct databases decided to merge their separate efforts to make optimal use of limited developer resources and maximize the curation output. All data manually curated by the MINT curators have been moved into the IntAct database at EMBL-EBI and are merged with the existing IntAct dataset. Both IntAct and MINT are active contributors to the IMEx consortium (http://www.imexconsortium.org). PMID:24234451

  4. Measuring the Recovery Orientation of ACT

    Salyers, Michelle P.; Stull, Laura G.; Rollins, Angela L.; McGrew, John H.; Hicks, Lia J.; Thomas, Dave; Strieter, Doug

    2014-01-01

    Background Approaches to measuring recovery orientation are needed, particularly for programs that may struggle with implementing recovery-oriented treatment. Objective A mixed methods comparative study was conducted to explore effective approaches to measuring recovery orientation of Assertive Community Treatment (ACT) teams. Design Two ACT teams exhibiting high and low recovery orientation were compared using surveys, treatment plan ratings, diaries of treatment visits, and team-leader-reported treatment control mechanisms. Results The recovery-oriented team differed on one survey measure (higher expectations for consumer recovery), treatment planning (greater consumer involvement and goal-directed content), and use of control mechanisms (less use of representative payee, agency-held lease, daily medication delivery, and family involvement). Staff and consumer diaries showed the most consistent differences (e.g., conveying hope and choice) and were the least susceptible to observer bias, but had the lowest response rates. Conclusions Several practices differentiate recovery orientation on ACT teams, and a mixed-methods assessment approach is feasible. PMID:23690285

  5. Pay Equity Act, 17 May 1988.

    1988-01-01

    This document contains major provisions of the 1988 Pay Equity Act of Prince Edward Island, Canada. (Nova Scotia enacted similar legislation in 1988.) This act defines "female-dominated class" or "male-dominated class" as a class with 60% or more female or male incumbents, respectively. The objective of this act is to achieve pay equity among public sector employers and employees by identifying systemic gender discrimination through a comparison of the relative wages and value of the work performed by female- and male-dominated classes. The value of work is to be determined by considering the skill, effort, and responsibility required by the work as well as the conditions under which it is performed. A difference in wages between a female- and male-dominated class performing work of equal or comparable value can be justified by a formal performance appraisal system or formal seniority system that does not discriminate on the basis of gender or by a skills shortage which requires a temporary inflation in wages to attract workers for a certain position. No wages shall be reduced to implement pay equity. Implementation of pay equity will include the work of bargaining agents to achieve agreement on salient points. Pay equity may be implemented in four stages over a period of 24 months.

  6. Federal Technology Transfer Act (FTTA)

    EPA's Federal Technology Transfer Act (FTTA) is a mechanism with which EPA can patent its inventions and license them to companies, through which innovative technologies can enter the marketplace to improve the environment and human health.

  7. Endangered Species Act Critical Habitat

    National Oceanic and Atmospheric Administration, Department of Commerce — Critical habitat (CH) is designated for the survival and recovery of species listed as threatened or endangered under the Endangered Species Act (ESA). Critical...

  8. Atomic Energy Authority Act 1986

    1986-01-01

    Under this Act the UKAEA is given power to borrow so that it can finance its capital expenditure programme, and will undertake a debt to the Secretary of State for Energy representing its assets. Power is given for the Government to guarantee such borrowing. The UKAEA has been organised financially on the basis of a trading fund. The Act came into force on 1 April 1986. (NEA) [fr

  9. The state civil responsibility for the concessionaire acts concerning to the environmental damages caused by the petroleum and natural gas economical exploration; A responsabilidade civil do estado pelos atos do concessionario no que tange aos danos ambientais causados pela exploracao economica do petroleo e gas natural

    Marinho, Karoline Lins Camara [Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN (Brazil)

    2004-07-01

    By means of the concession institute, the administration provides, indirectly, its originary functions gestion, acting and stimulating the development of the private activity with the exclusive attribution to the particulars, of rights and faculties, having always as a bigger aim the public interest. That being so, with the advent of the Amendment number 9 of the 1988 Federal Constitution, the State went by realizing concessions in the petroleum and natural gas field, allowing the market aperture, which was, before the amendment, monopolized by a state company - PETROBRAS. However, in spite of concede the exploration, production and transport rights of this product, the State keep itself playing the role of the collective interest prosecutor, and in such case, must be responsible for the damages that perhaps its concessionaires cause. The present research is purposed to study specifically the environment damages caused by the petroleum industry concessionaires, in what concerns to the state civil responsibility, using the many interpretative methods of the Law, like the historical, the systematic and the teleological, in the scope of contribute for a juridic culture each time stronger in the defense of the diffuse rights, in specific the environment rights. (author)

  10. 7 CFR 956.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 956.2 Section 956.2 Agriculture Regulations of... OF SOUTHEAST WASHINGTON AND NORTHEAST OREGON Definitions § 956.2 Act. Act means Public Act No. 10... Agreement Act of 1937, as amended (Sec. 1-19, 48 Stat. 31, as amended; 7 U.S.C. 601 et seq.). ...

  11. 7 CFR 983.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 983.2 Section 983.2 Agriculture Regulations of... NEW MEXICO Definitions § 983.2 Act. Act means Public Act No. 10, 73rd Congress (May 12, 1933), as amended and as re-enacted and amended by the Agricultural Marketing Order Act of 1937, as amended (48 Stat...

  12. 7 CFR 930.1 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 930.1 Section 930.1 Agriculture Regulations of... Definitions § 930.1 Act. Act means Public Act No. 10, 73d Congress (May 12, 1933), as amended, and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (48 Stat. 31, as...

  13. 7 CFR 984.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 984.2 Section 984.2 Agriculture Regulations of... Handling Definitions § 984.2 Act. Act means Public Act No. 10, 73d Congress, as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (7 U.S.C. 601 et seq.). ...

  14. 7 CFR 925.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 925.2 Section 925.2 Agriculture Regulations of... SOUTHEASTERN CALIFORNIA Definitions § 925.2 Act. Act means Public Act No. 10, 73d Congress (May 12, 1933), as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (48...

  15. 7 CFR 917.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 917.2 Section 917.2 Agriculture Regulations of... Order Regulating Handling Definitions § 917.2 Act. Act means Public Act No. 10, 73d Congress (May 12, 1933), as amended, and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as...

  16. 7 CFR 915.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 915.2 Section 915.2 Agriculture Regulations of... Regulating Handling Definitions § 915.2 Act. Act means Public Act No. 10, 73d Congress (May 12, 1933), as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (48...

  17. 7 CFR 959.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 959.2 Section 959.2 Agriculture Regulations of... Handling Definitions § 959.2 Act. Act means Public Act No. 10, 73d Congress, as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (sections 1-19, 48 Stat...

  18. 7 CFR 1260.128 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1260.128 Section 1260.128 Agriculture... Promotion and Research Order Definitions § 1260.128 Act. Act means the Beef Promotion and Research Act of 1985, Title XVI, Subtitle A of the Food Security Act of 1985, Pub. L. 99-198 and any amendments thereto. ...

  19. 7 CFR 982.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 982.2 Section 982.2 Agriculture Regulations of... Order Regulating Handling Definitions § 982.2 Act. Act means Public Act No. 10, 73d Congress, as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (7 U.S.C...

  20. 7 CFR 932.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 932.2 Section 932.2 Agriculture Regulations of... Handling Definitions § 932.2 Act. Act means Public Act No. 10, 73d Congress (May 12, 1933) as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (48 Stat. 31...

  1. 7 CFR 981.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 981.2 Section 981.2 Agriculture Regulations of... Handling Definitions § 981.2 Act. Act means Public Act No. 10, 73d Congress, as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (48 Stat. 31, as amended...

  2. 7 CFR 906.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 906.2 Section 906.2 Agriculture Regulations of... GRANDE VALLEY IN TEXAS Order Regulating Handling Definitions § 906.2 Act. Act means Public Act No. 10, 73d Congress, as amended and as re-enacted and amended by the Agricultural Marketing Agreement Act of...

  3. 7 CFR 966.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 966.2 Section 966.2 Agriculture Regulations of... Handling Definitions § 966.2 Act. Act means Public Act No. 10, 73d Congress, as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (48 Stat. 31, as amended...

  4. 7 CFR 916.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 916.2 Section 916.2 Agriculture Regulations of... Regulating Handling Definitions § 916.2 Act. Act means Public Act No. 10, 73d Congress (May 12, 1933), as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (48...

  5. 7 CFR 993.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 993.2 Section 993.2 Agriculture Regulations of... Regulating Handling Definitions § 993.2 Act. Act means Public Act No. 10, 73d Congress, as amended and reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (7 U.S.C. 601 et seq.). ...

  6. 7 CFR 35.1 - Act.

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Act. 35.1 Section 35.1 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices... Definitions § 35.1 Act. Act or Export Grape and Plum Act means “An Act to promote the foreign trade of the...

  7. 7 CFR 923.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 923.2 Section 923.2 Agriculture Regulations of... IN WASHINGTON Order Regulating Handling Definitions § 923.2 Act. Act means Public Act No. 10, 73d... Act of 1937, as amended (48 Stat. 31, as amended; 7 U.S.C. 601 et seq.; 68 Stat. 906, 1047). ...

  8. 7 CFR 927.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 927.2 Section 927.2 Agriculture Regulations of... Regulating Handling Definitions § 927.2 Act. Act means Public Act No. 10, 73d Congress (May 12, 1933), as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (48...

  9. 7 CFR 946.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 946.2 Section 946.2 Agriculture Regulations of... Regulating Handling Definitions § 946.2 Act. Act means Public Act No. 10, 73d Congress, as amended and reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (48 Stat. 31, as...

  10. 7 CFR 989.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 989.2 Section 989.2 Agriculture Regulations of... CALIFORNIA Order Regulating Handling Definitions § 989.2 Act. Act means Public Act No. 10, 73d Congress, as amended, and as re-enacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended...

  11. 7 CFR 1170.2 - Act.

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Act. 1170.2 Section 1170.2 Agriculture Regulations of... Orders; Milk), DEPARTMENT OF AGRICULTURE DAIRY PRODUCT MANDATORY REPORTING § 1170.2 Act. Act means the Agricultural Marketing Act of 1946, 7 U.S.C. 1621 et seq., as amended by the Dairy Market Enhancement Act of...

  12. 7 CFR 987.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 987.2 Section 987.2 Agriculture Regulations of... RIVERSIDE COUNTY, CALIFORNIA Order Regulating Handling Definitions § 987.2 Act. Act means Public Act No. 10, 73d Congress, as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of...

  13. 7 CFR 948.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 948.2 Section 948.2 Agriculture Regulations of... Regulating Handling Definitions § 948.2 Act. Act means Public Act No. 10 73d Congress, as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (sections 1-19, 48...

  14. 7 CFR 922.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 922.2 Section 922.2 Agriculture Regulations of... WASHINGTON Order Regulating Handling Definitions § 922.2 Act. Act means Public Act No. 10, 73d Congress (May 12, 1933), as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of...

  15. 7 CFR 33.1 - Act.

    2010-01-01

    ... Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices... AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.1 Act. Act and Export Apple Act are synonymous and mean “An act to promote the foreign trade of the United States in apples to protect the reputation of...

  16. A perspective on the PCPNDT Act

    A Murali Mohan Patnaik

    2012-01-01

    Full Text Available Background: An important modern diagnostic tool, used for monitoring pregnancy and genetic defects; the ultrasound machine, has also become a selective killer of the female child. The male child preference in India was responsible for female infanticides in the past. With easy availability and accessibility of USG, a shift has occurred from infanticide to feticide, although female infanticides still continue. In the process doctors are blamed as "merchants of death". Peeved and pressed by national and internal agencies for the declining female child ratio (0-6 years, the Government of India reacted by enacting a stringent PC-PNDT Act almost solely aimed at doctors to prevent them from advertising and disclosing the sex of the fetus to the pregnant woman or her relatives. Since the enactment, hundreds of cases have been launched against the doctors. Aims: 1. In order to stand up to the law important sections and rules of the PC-PNDT Act have been analyzed for the benefit of our colleagues. 2. The Indian legal system rests the "burden of proof" on the prosecution. In two sections of The Act, these have been done away with. Instead, the accused doctor has to prove himself innocent. Therefore a demand has been made to make suitable amendments to The Act in this regard. 3. The inclusion of column numbers 9-19 in the form ′F′ is not relevant for USG clinics/ imaging centers; inaccurate filling of which may attract a prison sentence of 3 years. This irrelevance has to be deleted. 4. Some suggestions.

  17. New Croatian Act on Ionizing Radiation Protection

    Grgic, S.

    1998-01-01

    According to the new Croatian Act on ionizing radiation protection which is in a final stage of genesis, Ministry of Health of the Republic of Croatia is the governmental body responsible for all aspects relating sources of ionizing radiation in Croatia: practices, licenses, users, transport, in medicine and industry as well, workers with sources of ionizing radiation, emergency preparedness in radiological accidents, storage of radioactive wastes, x-ray machines and other machines producing ionizing radiation and radioactive materials in the environment. Ministry of Health is responsible to the Government of the Republic of Croatia, closely collaborating with the Croatian Radiation Protection Institute, health institution for the performance of scientific and investigation activities in the field of radiation protection. Ministry of Health is also working together with the Croatian Institute for the Occupational Health. More emphasis has been laid on recent discussion among the world leading radiation protection experts on justification of the last recommendations of the ICRP 60 publication. (author)

  18. 32 CFR 326.5 - Responsibilities.

    2010-07-01

    ... Privacy Act Coordinator, NRO: (1) Establishes, issues, and updates policy for the NRO Privacy Act Program... Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM NATIONAL RECONNAISSANCE OFFICE PRIVACY ACT PROGRAM § 326.5 Responsibilities. (a) The Director, NRO (DNRO...

  19. 32 CFR 324.4 - Responsibilities.

    2010-07-01

    ... Privacy Act Officer. (1) Establishes, issues and updates policy for the DFAS Privacy Act Program and... Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DFAS PRIVACY ACT PROGRAM General information § 324.4 Responsibilities. (a) Director, DFAS. (1) Ensures...

  20. 75 FR 66385 - Protecting Tenants at Foreclosure Act: Guidance on Notification Responsibilities Under the Act...

    2010-10-28

    .... Often, tenants residing as leaseholders in residential properties become collateral victims in addition... Residential Property,'' published in the Federal Register on June 24, 2009. Specifically, today's notice... accepting conveyance of an occupied property because of foreclosure of an FHA mortgage, the occupant is...

  1. To act or not to act: responses to electronic health record prompts by family medicine clinicians.

    Zazove, Philip; McKee, Michael; Schleicher, Lauren; Green, Lee; Kileny, Paul; Rapai, Mary; Mulhem, Elie

    2017-03-01

    A major focus of health care today is a strong emphasis on improving the health and quality of care for entire patient populations. One common approach utilizes electronic clinical alerts to prompt clinicians when certain interventions are due for individual patients being seen. However, these alerts have not been consistently effective, particularly for less visible (though important) conditions such as hearing loss (HL) screening. We conducted hour-long cognitive task analysis interviews to explore how family medicine clinicians view, perceive, and use electronic clinical alerts, and to utilize this information to design a more effective alert using HL identification and referral as a model diagnosis. Four key direct barriers were identified that impeded alert use: poor standardization and formatting, time pressures in primary care, clinic workflow variations, and mental models of the condition being prompted (in this case, HL). One indirect barrier was identified: electronic health record and institution/government regulations. We identified that clinicians' mental model of the condition being prompted was probably the major barrier, though this was often expressed as time pressure. We discuss solutions to each of the 5 identified barriers, such as addressing physicians' mental models, by focusing on physicians' expertise rather than knowledge to improve their comfort when caring for patients with the conditions being prompted. To unleash the potential of electronic clinical alerts, electronic health record and health care institutions need to address some key barriers. We outline these barriers and propose solutions. © The Author 2017. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  2. Responsible investors acting on climate change. Investors acting on climate change. Climate: Investors take action

    Simon, Marie; Blanc, Dominique; Husson-Traore, Anne-Catherine; Amiell, Alison; Barochez, Aurelie de; Conti, Sophie; Kamelgarn, Yona; Bonnet, Olivier; Braman, Stuart; Chenet, Hugues; Fisher, Remco; Hellier, Mickael; Horster, Maximilian; Kindelbacher, Sophie; Leaton, James; Lieblich, Sebastien; Neuneyer, Dustin; Lenoel, Benjamin; Smart, Lauren; Torklep Meisingset, Christine

    2015-02-01

    Some investors are willing to lower the carbon emission financed by their investment, recognizing that climate change has financial impacts. At first they measure the carbon footprint of their portfolio, than initiate shareholder engagement actions at oil and gas companies, publish list of exclusion composed of the most carbon-intensive companies and ask for ex fossil fuels indices. In June 2015, Novethic launches the first actualisation of its study released on February 2015 on the mobilisation of investors on climate change over the whole 2015 year. The trend is gaining momentum since more than 200 additional investors publicly disclosed commitments to integrate climate risk into their investment and management practices. In September 2015, for its second update of the report on how investors are taking action on climate change, more than 800 entities were screened. As a key result, investor's actions gain momentum: approaches are growing in number and becoming more expert, divestments are widespread in Europe, and green investments promises are more ambitious. The last edition of November 2015 highlights and scans an exclusive panel of 960 investors worth Euro 30 trillion of assets who have made steps forward to tackle climate change. During the last 8 months, their number has almost increased twofold. This document brings together the first edition of Novethic's study and its three updates

  3. Corporate responses to stakeholder activism

    Uldam, Julie; Krause Hansen, Hans

    2017-01-01

    Corporations are increasingly expected to act responsibly. The purpose of this paper is to examine two types of corporate responses to these expectations: overt and covert responses. Specifically, it examines oil companies’ involvement in multi-stakeholder initiatives and sponsorships (overt...

  4. What is new in the Act on Nuclear Safety

    Novosel, N.

    2005-01-01

    The Act on Nuclear Safety was passed by the Croatian Parliament on 15 October 2003, and published in Narodne novine (official journal) No. 173/03. This Act regulates safety measures for using nuclear materials and equipment, regulates nuclear activities, and establishes the National Office for Nuclear Safety. The new act supersedes the Act on Protective Measures Against Ionising Radiation and Safety in the Use of Nuclear Facilities and Installations (Narodne novine No. 18/81) and the Act on Protection against Ionising Radiation and Special Safety Measures in Using Nuclear Energy (Narodne novine No. 53/91). Regulations based on the latter Act shall apply until they are replaced by new regulations based on the Act on Nuclear Safety. Provisions of this Act apply for nuclear activities, nuclear materials and specified equipment. Croatia does not have nuclear facilities on its territory, but a Croatian power utility company owns 50% of the Nuclear Power Plant Krsko on the territory of Slovenia. In that respect, Croatia has assumed responsibilities defined by the Agreement between the Government of the Republic of Slovenia and the Government of the Republic of Croatia on the Regulation of the Status and Other Legal Relationships, Connected with Investments in the Krsko Nuclear Power Plant, its Exploitation and Decommissioning (Narodne novine No. 9/02, International Agreements). Having accessioned international conventions and agreements, Croatia has also assumed the responsibility to implement their provisions. In the process of European and international integrations, Croatia has to harmonize with the European and international standards in nuclear safety.(author)

  5. 7 CFR 1210.302 - Act.

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE WATERMELON RESEARCH AND PROMOTION PLAN Watermelon Research and Promotion Plan Definitions § 1210.302 Act. Act means the Watermelon...

  6. 3 CFR - Ensuring Responsible Spending of Recovery Act Funds

    2010-01-01

    ... long-term public benefits by, for example, investing in technological advances in science and health to... protection, and other infrastructure that will provide long-term economic benefits; fostering energy..., aquarium, zoo, golf course, or swimming pool.” (b) In exercising their available discretion to commit...

  7. DRIVING CORPORATE SOCIAL RESPONSIBILITY (CSR ...

    henk

    express reference is made to companies' social responsibility (which is commonly referred to as CSR),4 ...... deceptive representations. S 22 of the Act ... South Africa, which requires transparent and effective communication with stakeholders ...

  8. Air traffic security act unconstitutional

    Heller, W.

    2006-01-01

    In the interest of more effective protective measures against terrorist attacks, the German federal parliament inter alia added a clause to the Air Traffic Security Act (Sec. 14, Para. 3, Air Traffic Security Act) empowering the armed forces to shoot down aircraft to be used as a weapon against human lives. In Germany, this defense possibility has been discussed also in connection with deliberate crashes of hijacked aircraft on nuclear power plants. The 1 st Division of the German Federal Constitutional Court, in its decision of February 15, 2006, ruled that Sec. 14, Para. 3, Air Traffic Security Act was incompatible with the Basic Law and thus was null and void (file No. 1 BvR 357/05) for two reasons: - There was no legislative authority on the part of the federal government. - The provision was incompatible with the basic right of life and the guarantee of human dignity as enshrined in the Basic Law. (orig.)

  9. Environment Protection (Alligator Rivers Region) Act 1978, No.28

    1978-01-01

    The main object of this Act is to provide for the appointment of a Supervising Scientist responsible for supervising protection of the environment in the Alligator Rivers Region of the Northern Territory from the effects of uranium mining operations. His functions include advising the competent Minister on the effects of uranium mining operations on the environment and on standards, practices and procedures for its protection and restoration. The Act also sets up a Co-ordinating Committee responsible for programmes for research into the environmental effects of such mining operations and also keeping under review standards, practices and procedures for environmental protection in relation thereto. Finally the Act provides for the establishment of a Research Institute managed by the Supervising Scientist, to promote and assist in research as well as to collect information on the environmental effects of uranium mining operations. (NEA) [fr

  10. The Problem of Agency; How Humans Act, How Machines Act

    Rose, Jeremy; Jones, M.; Truex, D.

    2003-01-01

    A long-standing debate in the IS literature concerns the relationship between technology and organization. Is it technology that acts on organizations, or humans that determine how technology is used? Proposals for a middle way between the extremes of technological and social determinism have bee...

  11. HASP: human acts simulation program

    Asai, Kiyoshi; Kambayashi, Shaw; Higuchi, Kenji; Kume, Etsuo; Otani, Takayuki; Fujii, Minoru; Uenaka, Junji; Fujisaki, Masahide.

    1990-01-01

    The Human Acts Simulation Program (HASP) aims computer simulations of mechanized human acts in a nuclear plant by a human shaped intelligent robot. The HASP has started as a ten-year program at Japan Atomic Energy Research Institute since 1987. The purposes of HASP are threefold as follows; development of basic and generalized design technologies for intelligent robots, development of basic technologies for an advanced intelligent and automatic nuclear power plant, and provision of artificial intelligence techniques for researchers in the nuclear field. In this paper, the contents of the HASP are described. (author)

  12. The State Surveillance over Nuclear Safety of Nuclear Facilities Act No. 28/1984

    1995-01-01

    The Act lays down responsibilities of the Czechoslovak Atomic Energy Commission in the field of state surveillance over nuclear safety of nuclear facilities; determines the responsibilities of nuclear safety inspectors in their inspection activities; specifies duties of bodies and corporations responsible for nuclear safety of nuclear facilities; stipulates the obligation to set up emergency plans; and specifies penalties imposed on corporations and individuals for noncompliance with nuclear safety provisions. The Act entered into force on 4 April 1984. (J.B.)

  13. Alphabet Soup: ERP, CT, and ACT for OCD

    Tolin, David F.

    2009-01-01

    The present article comments on the case conference presented in this issue, namely, Himle and Franklin's (Himle & Franklin, 2009) exposure and response prevention (ERP); Chosak and colleagues' (Chosak, Marques, Fama, Renaud, & Wilhelm, 2009) cognitive therapy (CT); and (Twohig, 2009) Acceptance and Commitment Therapy (ACT). Two questions are…

  14. 75 FR 27348 - Public Health Services Act; Delegation of Authority

    2010-05-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Public Health Services Act; Delegation of Authority Notice is hereby given that I have delegated to the Director, Office of Public Health Preparedness and Response (OPHPR), with authority to redelegate, the authority to...

  15. 78 FR 45925 - Clean Water Act: Availability of List Decisions

    2013-07-30

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9840-5] Clean Water Act: Availability of List Decisions AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of availability. SUMMARY: This notice announces the availability of EPA's Responsiveness Summary Concerning EPA's May 9, 2013 Public Notice of...

  16. Needed: Reincarnation of National Defense Education Act of 1958

    Harris, Mary M.; Miller, James R.

    2005-01-01

    This paper reviews the historical and current response of the United States to threats to its world leadership in scientific endeavors, with particular attention to the National Defense Education Act of 1958. The current status of the United States in mathematics, science, and engineering education is reviewed with respect to K-12 student…

  17. Sport supporting act: terminology issues

    Petr Vlček

    2013-01-01

    Full Text Available BACKGROUND: The text deals with terminology issues from an interdisciplinary point of view. It is based on two different disciplines, law and kinanthropology, in an area of their overlap. AIM: The aim of the author is to point out some possible legislative problems, which could arise due to the current reading of the sport supporting act (Act no. 115/2001. The second aim of the author is to contribute to the discussion of kinantropologists (possibly also the educational researchers and lawyers and to stress the importance of the systematic approach to terminology formulation. METHODS: The author uses the method of language interpretation. We also use the basic analytical methods, induction and deduction, while we stress the systematic approach to the term formulation. RESULTS: The analysis of the sport supporting act terminology shows some specific legislative problems, which could arise due to the definition of sport in the sport supporting act. The author discusses a possible alternative solution. CONCLUSION: According to the opinion of the author, clear, obvious and unified terminology of kinantropologists as specialists in their discipline should represent a source, from which other sciences could derive their terminology. Defined and inexpert terminology used in other disciplines should not be used as an argument for its adopting in kinanthropology.

  18. Against acts of nuclear terrorism

    Heller, W.

    2007-01-01

    The Act on the International Convention of the United Nations of April 13, 2005 on Combating Acts of Nuclear Terrorism was promulgated in the German Federal Gazette and entered into force one day later. The Convention expresses the deep concern about the worldwide escalation of all kinds and manifestations of acts of terrorism. What was true in April 2005 (the year the UN convention was adopted) is even more true today. At the same time, however, the Convention recognizes the right of all nations to develop and use nuclear power for peaceful purposes, acknowledging their justified interest in the possible benefits of the peaceful uses of nuclear power. As the Convention was signed in German still during the term of office of the Red-Green government, this passage is a remarkable acceptance of the realities of the world and past peaceful uses of nuclear power in Germany. Whether or not the convention will become an effective instrument to be used against acts of nuclear terrorism and threats depends on its entering into force after deposition of 22 ratification documents, and on as many states as possible acceding to it. Irrespective of these aspects, action in the spirit of the Convention should be taken now, criminal law should be adapted, and international cooperation should be improved and strengthened. (orig.)

  19. The American Inventors Protection Act

    Hoffmann, Arvid O.I.; Kleimeier, Stefanie; Mimiroglu, Nagihan; Pennings, Joost M.E.

    2018-01-01

    We examine the impact of innovation disclosure through patenting on firms' cost of debt, focusing on the American Inventors Protection Act (AIPA) as an exogenous shock in innovation disclosure regulation. Post-AIPA, firms have an incentive to apply for patents only if commercial success is likely.

  20. Paraconsistent semantics of speech acts

    Dunin-Kȩplicz, Barbara; Strachocka, Alina; Szałas, Andrzej; Verbrugge, Rineke

    2015-01-01

    This paper discusses an implementation of four speech acts: assert, concede, request and challenge in a paraconsistent framework. A natural four-valued model of interaction yields multiple new cognitive situations. They are analyzed in the context of communicative relations, which partially replace

  1. Nuclear Activities (Prohibitions) Act 1983

    1983-01-01

    The purpose of this Act is to protect the health and safety of the people of Victoria and its environment by prohibiting nuclear activities from being carried out and regulating the possession of certain nuclear material in a manner consistent with assisting Australia in meeting its international nuclear non-proliferation objectives. (NEA) [fr

  2. Dumping at Sea Act 1974

    1974-01-01

    This Act enables the United Kingdom Government to ratify both the Oslo Convention of 1972 for the Prevention of Marine Pollution by Dumping from Ships and Aircraft and the London Convention of 1972 on the Prevention of Marine Pollution by Dumping of Wastes and Other Matter. (NEA) [fr

  3. Affordable Care Act and Women

    ... quality care for older women, and ends the gender discrimination that requires women to pay more for the same insurance coverage ... the Affordable Care Act and 13 million more women will gain coverage by 2016. Maternity Coverage Preventive ... Expanded Insurance Coverage Endnotes Download "rb. ...

  4. 22 CFR 901.10 - Act.

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Act. 901.10 Section 901.10 Foreign Relations FOREIGN SERVICE GRIEVANCE BOARD GENERAL Meanings of Terms As Used in This Chapter § 901.10 Act. Act means the Foreign Service Act of 1980 (Pub. L. 96-465, October 17, 1980), as amended. [56 FR 55458, Oct. 28...

  5. 7 CFR 1280.101 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1280.101 Section 1280.101 Agriculture... INFORMATION ORDER Lamb Promotion, Research, and Information Order Definitions § 1280.101 Act. Act means the Commodity Promotion, Research, and Information Act of 1996 (7 U.S.C. 7411-7425; Pub. L. 104-127; 110 Stat...

  6. 7 CFR 1150.101 - Act.

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Act. 1150.101 Section 1150.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and... Definitions § 1150.101 Act. Act means Title I, Subtitle B, of the Dairy and Tobacco Adjustment Act of 1983...

  7. 12 CFR 541.2 - Act.

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Act. 541.2 Section 541.2 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY DEFINITIONS FOR REGULATIONS AFFECTING FEDERAL SAVINGS ASSOCIATIONS § 541.2 Act. The term Act means the Home Owners' Loan Act of 1933, as amended. ...

  8. 7 CFR 1250.302 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1250.302 Section 1250.302 Agriculture... Research and Promotion Order Definitions § 1250.302 Act. Act means the Egg Research and Consumer Information Act and as it may be amended (Pub. L. 93-428). ...

  9. 7 CFR 1207.302 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1207.302 Section 1207.302 Agriculture... Potato Research and Promotion Plan Definitions § 1207.302 Act. Act means the Potato Research and Promotion Act, Title III of Public Law 91-670, 91st Congress, approved January 11, 1971, 84 Stat. 2041, as...

  10. 7 CFR 985.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 985.2 Section 985.2 Agriculture Regulations of... SPEARMINT OIL PRODUCED IN THE FAR WEST Order Regulating Handling Definitions § 985.2 Act. Act means Public Act No. 10, 73d Congress, as amended, and reenacted and amended by the Agricultural Marketing...

  11. 7 CFR 1230.601 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1230.601 Section 1230.601 Agriculture... CONSUMER INFORMATION Procedures for the Conduct of Referendum Definitions § 1230.601 Act. The term Act means the Pork Promotion, Research, and Consumer Information Act of 1985 (7 U.S.C. 4801-4819) and any...

  12. 29 CFR 401.17 - Act.

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Act. 401.17 Section 401.17 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR LABOR-MANAGEMENT STANDARDS MEANING OF TERMS USED IN THIS SUBCHAPTER § 401.17 Act. Act means the Labor-Management Reporting and Disclosure Act...

  13. 7 CFR 1218.1 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1218.1 Section 1218.1 Agriculture Regulations of... INFORMATION ORDER Blueberry Promotion, Research, and Information Order Definitions § 1218.1 Act. Act means the Commodity Promotion, Research, and Information Act of 1996 (7 U.S.C. 7401-7425; Pub. L. 104-127; 110 Stat...

  14. 7 CFR 1216.1 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1216.1 Section 1216.1 Agriculture Regulations of... ORDER Peanut Promotion, Research, and Information Order Definitions § 1216.1 Act. Act means the Commodity Promotion, Research, and Information Act of 1996 (7 U.S.C. 7401-7425; Public Law 104-127, 110 Stat...

  15. 7 CFR 924.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 924.2 Section 924.2 Agriculture Regulations of... WASHINGTON AND IN UMATILLA COUNTY, OREGON Order Regulating Handling Definitions § 924.2 Act. Act means Public Act No. 10, 73d Congress (May 12, 1933), as amended and as re-enacted and amended by the Agricultural...

  16. 34 CFR 300.4 - Act.

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Act. 300.4 Section 300.4 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES... Definitions Used in This Part § 300.4 Act. Act means the Individuals with Disabilities Education Act, as...

  17. 7 CFR 1206.1 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1206.1 Section 1206.1 Agriculture Regulations of... Mango Promotion, Research, and Information Order Definitions § 1206.1 Act. Act means the Commodity Promotion, Research, and Information Act of 1996 (7 U.S.C. 7411-7425; Public Law 104-127; 110 Stat. 1029...

  18. 7 CFR 1220.600 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1220.600 Section 1220.600 Agriculture... CONSUMER INFORMATION Procedures To Request a Referendum Definitions § 1220.600 Act. Act means the Soybean, Promotion, Research, and Consumer Information Act set forth in title XIX, subtitle E, of the Food...

  19. 7 CFR 1205.302 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1205.302 Section 1205.302 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Research and Promotion Order Definitions § 1205.302 Act. Act means the Cotton Research and Promotion Act...

  20. 7 CFR 1212.1 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1212.1 Section 1212.1 Agriculture Regulations of..., Consumer Education, and Industry Information Order Definitions § 1212.1 Act. “Act” means the Commodity Promotion, Research, and Information Act of 1996, (7 U.S.C. 7411-7425), and any amendments to that Act. ...

  1. 7 CFR 1221.1 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1221.1 Section 1221.1 Agriculture Regulations of... INFORMATION ORDER Sorghum Promotion, Research, and Information Order Definitions § 1221.1 Act. Act means the Commodity Promotion, Research, and Information Act of 1996 (7 U.S.C. 7411-7425), and any amendments thereto. ...

  2. 7 CFR 1219.1 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1219.1 Section 1219.1 Agriculture Regulations of... INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.1 Act. Act means the Hass Avocado Promotion, Research, and Information Act of 2000, Public Law 106-387, 7 U.S.C. 7801-7813...

  3. 7 CFR 1220.101 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1220.101 Section 1220.101 Agriculture... CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.101 Act. The term Act means the Soybean Promotion, Research, and Consumer Information Act, subtitle E of title XIX, of the Food...

  4. 7 CFR 958.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 958.2 Section 958.2 Agriculture Regulations of... IN IDAHO, AND MALHEUR COUNTY, OREGON Order Regulating Handling Definitions § 958.2 Act. Act means Public Act No. 10, 73d Congress, as amended and as reenacted and amended by the Agricultural Marketing...

  5. 34 CFR 303.6 - Act.

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Act. 303.6 Section 303.6 Education Regulations of the..., Eligibility, and Other General Provisions § 303.6 Act. As used in this part, Act means the Individuals with Disabilities Education Act. (Authority: 20 U.S.C. 1400) ...

  6. 7 CFR 945.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 945.2 Section 945.2 Agriculture Regulations of... COUNTIES IN IDAHO, AND MALHEUR COUNTY, OREGON Order Regulating Handling Definitions § 945.2 Act. Act means Public Act No. 10, 73d Congress, as amended and as reenacted and amended by the Agricultural Marketing...

  7. 78 FR 4462 - Sunshine Act; Meeting Notice

    2013-01-22

    ... goals for 2013 5. Panel presentation and discussion on Succession Planning and Leadership Development... comment 7. Consider and act on other business 8. Consider and act on motion to adjourn the meeting... comment 8. Consider and act on other business 9. Consider and act on adjournment of meeting Institutional...

  8. 40 CFR 1508.2 - Act.

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Act. 1508.2 Section 1508.2 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY TERMINOLOGY AND INDEX § 1508.2 Act. Act means the National Environmental Policy Act, as amended (42 U.S.C. 4321, et seq.) which is also referred to as “NEPA.” ...

  9. Draft of a Fourth Act amending the Atomic Energy Act

    1976-01-01

    The bill comprises regulations concerning 1. the handling over and treatment of radioactive waste as well as its final storage under federal adminstration (article 87, section 3, sentence 1 Basic Law), 2. authorizations regarding the issuing of statuatory orders supplementing and extending sections 11 and 12 of the Atomic Energy Act, particulary in aim of the rationalization of licensing and the carrying-out of governmental supervision, 3. supplementing penal provisions. (LN) [de

  10. Sharing data under the 21st Century Cures Act.

    Majumder, Mary A; Guerrini, Christi J; Bollinger, Juli M; Cook-Deegan, Robert; McGuire, Amy L

    2017-12-01

    On 13 December 2016, President Obama signed the 21st Century Cures Act ("the Act") into law. Many of its provisions support the creation of an "Information Commons," an ecosystem of separate but interconnected initiatives that facilitate open and responsible sharing of genomic and other data for research and clinical purposes. For example, the Act supports the National Institutes of Health in mandating data sharing, provides funding and guidance for the large national cohort program now known as All of Us, expresses congressional support for a global pediatric study network, and strengthens patient access to health information. The Act also addresses potential barriers to data sharing. For example, it makes the issuance of certificates of confidentiality automatic for federally funded research involving "identifiable, sensitive" information and strengthens the associated protections. At the same time, the Act exacerbates or neglects several challenges, for example, increasing complexity by adding a new definition of "identifiable" and failing to address the financial sustainability of data sharing and the scope of commercialization. In sum, the Act is a positive step, yet there is still much work to be done before the goals of broad data sharing and utilization can be achieved.

  11. Responsibility and Integrated Thinking

    Robinson, SJ

    2014-01-01

    Integrated thinking is essentially focused in dialogue and communication. This is partly because relationships and related purpose focus on action, which itself acts as a means of integration, and partly because critical dialogue enables better, more responsive, integrated thinking and action.

  12. 7 CFR 905.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 905.2 Section 905.2 Agriculture Regulations of... TANGELOS GROWN IN FLORIDA Order Regulating Handling Definitions § 905.2 Act. Act means Public Act No. 10... Agreement Act of 1937, as amended. (48 Stat. 31, as amended; 7 U.S.C. 601 et seq.; 68 Stat. 906, 1047.) ...

  13. 7 CFR 955.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 955.2 Section 955.2 Agriculture Regulations of... § 955.2 Act. Act means Public Act No. 10, 73d Congress (May 12, 1933), as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (Sec. 1-19, 48 Stat. 31, as...

  14. 7 CFR 920.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 920.2 Section 920.2 Agriculture Regulations of... § 920.2 Act. Act means Public Act No. 10, 73d Congress (May 12, 1933), as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (48 Stat. 31, as amended; 7 U.S.C...

  15. 7 CFR 929.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 929.2 Section 929.2 Agriculture Regulations of... ISLAND IN THE STATE OF NEW YORK Order Regulating Handling Definitions § 929.2 Act. Act means Public Act... Marketing Agreement Act of 1937, as amended (secs. 1-19, 48 Stat. 31, as amended; 7 U.S.C. 601-674). ...

  16. 7 CFR 947.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 947.2 Section 947.2 Agriculture Regulations of... Definitions § 947.2 Act. Act means Public Act No. 10, 73d Congress, as amended and as reenacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (48 Stat. 31, as amended; 7 U.S.C. 601 et...

  17. 29 CFR 4.103 - The Act.

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true The Act. 4.103 Section 4.103 Labor Office of the Secretary... Contract Act Introductory § 4.103 The Act. The McNamara-O'Hara Service Contract Act of 1965 (Pub. L. 89-286, 79 Stat. 1034, 41 U.S.C. 351 et seq.), hereinafter referred to as the Act, was approved by the...

  18. 7 CFR 953.2 - Act.

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Act. 953.2 Section 953.2 Agriculture Regulations of... Order Regulating Handling Definitions § 953.2 Act. Act means Public Act No. 10, 73d Congress, as amended and as re-enacted and amended by the Agricultural Marketing Agreement Act of 1937, as amended (7 U.S.C...

  19. 7 CFR 1160.101 - Act.

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Act. 1160.101 Section 1160.101 Agriculture Regulations... Definitions § 1160.101 Act. Act means the Fluid Milk Promotion Act of 1990, Subtitle H of Title XIX of the Food, Agriculture, Conservation, and Trade Act of 1990, Public Law 101-624, 7 U.S.C. 6401-6417, and any...

  20. Zákon DREAM Act: Finální řešení?

    Toloch, Jan

    2015-01-01

    This thesis describes DREAM Act, a legislative proposal discussed in the US Congress between 2001 and 2011. The Act proposes a pathway to legal citizenship for children of undocumented immigrants. The thesis aims to find whether the children of illegal immigrants should be held accountable and face deportations, even though they were not responsible for entering the U.S. illegally? It also discusses whether implementation of the DREAM Act is a convenient solution of governmental reform of the...

  1. "Current Good Manufacturing Practices" and the Federal Food, Drug and Cosmetic Act

    Goldstein, Beth F.

    1995-01-01

    The Food and Drug Administration (hereinafter, FDA) regulates food, drugs, and cosmetics in order to ensure that these products are safe and truthfully labelled. As part of its responsibilities under the Federal Food, Drug, and Cosmetic Act (hereinafter, Act), the FDA monitors the manufacturing practices of companies involved in the production of food, drugs, and medical devices. The manufacturing practices used by these companies must comply with certain standards, identified in the Act as "...

  2. The 1990 Clean Air Act amendments

    Torrens, I.M.; Cichanowicz, J.E.; Platt, J.B.

    1992-01-01

    The impacts of the 1990 Clean Air Act Amendments on utilities are substantial, presenting a host of new technical challenges, introducing new business risks, changing costs of electric generation, creating new winners and losers, and calling for new organizational responses capable of dealing with the complexity and short time for decisions. The magnitude of costs and unknowns puts clean air compliance into a new league of energy issues, in which the decisions utilities must make are not simply technological or engineering economic choices, but rather are very complex business decisions with numerous stakeholders, pitfalls, and opportunities. This paper summarizes the key regulatory requirements of the CAAA, outlines compliance options and questions facing the utility industry, and addresses how utility strategic business decisions could be affected

  3. Radiation Act, promulgated on May 8,1997

    1997-01-01

    The Radiation Act was passed by the Estonian Parliament on 23 Apr 1997 and promulgated by the President on 8 May 1997. It is the principal legal instrument in the field of radiation protection for workers, the public and the environment. The Act is based on the concepts, principles, terminology and dose limits stipulated in the Basic Safety Standards (IAEA Safety Series No. 115-1) and the EC Directive 96/29/EURATOM. The Radiation Act defines the institutional framework for, and establishes the rules applicable to, the use of ionising radiation, the detention of radiation sources, the transport of radioactive materials, radioactive waste disposal and other activities which cause or may cause harm to health or to the environment. It also contains some general provisions on radioactive waste management, import and export of such wastes and the prohibition against importing radioactive waste for disposal purposes. The Act deals solely with radiation protection; all other nuclear activities are to be covered by other specific laws. The Estonian Radiation Protection Centre is empowered under the Act to inspect sources of radiation exposure and to register dose and source data. It is generally responsible for enforcing the provisions of the Act, although the details of the medical checks for radiation workers are governed by rules established by the Minister for Social Affairs. Chapter 3 of the Radiation Act contains detailed provisions on dose limits for the following categories of exposure to ionising radiation. The Act provides that Government and nominated Ministers be empowered to enact implementing regulations on exemption levels, requirements to ensure observance of the stipulated dose limits, qualification procedures for radiation workers, medical checks of radiation workers, medical applications of ionising radiation, packaging and safety procedures for radiation sources and rules for handling radioactive waste

  4. Guide to the Federal Act for Protection against Nuisances

    Thomas, J.; Wiedemann, R.

    1980-07-01

    The Federal Act for Protection against Nuisances contains all legal provisions related to pollution, noise, convulsions and shocks, thermal effects and similar effects on the environment. Apart from provisions of the actual Act for Protection against Nuisances, provisions related to nuisances are to be found in a number of legal fields. The authors provide a handy, completable survey on all relevant laws, ordinances, administrative regulations and directives issued by the Government of the federation and its individual states, and on the authorities responsible for their execution. The manual helps improve the transparency of legal provisions and adminstrative competences. (HSCH) [de

  5. Reconsidering Food Reward, Brain Stimulation, and Dopamine: Incentives Act Forward.

    Newquist, Gunnar; Gardner, R Allen

    2015-01-01

    In operant conditioning, rats pressing levers and pigeons pecking keys depend on contingent food reinforcement. Food reward agrees with Skinner's behaviorism, undergraduate textbooks, and folk psychology. However, nearly a century of experimental evidence shows, instead, that food in an operant conditioning chamber acts forward to evoke species-specific feeding behavior rather than backward to reinforce experimenter-defined responses. Furthermore, recent findings in neuroscience show consistently that intracranial stimulation to reward centers and dopamine release, the proposed reward molecule, also act forward to evoke inborn species-specific behavior. These results challenge longstanding views of hedonic learning and must be incorporated into contemporary learning theory.

  6. False memories for aggressive acts.

    Laney, Cara; Takarangi, Melanie K T

    2013-06-01

    Can people develop false memories for committing aggressive acts? How does this process compare to developing false memories for victimhood? In the current research we used a simple false feedback procedure to implant false memories for committing aggressive acts (causing a black eye or spreading malicious gossip) or for victimhood (receiving a black eye). We then compared these false memories to other subjects' true memories for equivalent events. False aggressive memories were all too easy to implant, particularly in the minds of individuals with a proclivity towards aggression. Once implanted, the false memories were indistinguishable from true memories for the same events, on several dimensions, including emotional content. Implications for aggression-related memory more generally as well as false confessions are discussed. Copyright © 2013 Elsevier B.V. All rights reserved.

  7. Clean Air Act. Revision 5

    1994-02-15

    This Reference Book contains a current copy of the Clean Air Act, as amended, and those regulations that implement the statute and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. This Reference Book has been completely revised and is current through February 15, 1994.

  8. 78 FR 29659 - Forfeiture Procedures Under the Endangered Species Act and the Lacey Act Amendments

    2013-05-21

    .... APHIS-2007-0086] RIN 0579-AD50 Forfeiture Procedures Under the Endangered Species Act and the Lacey Act... Endangered Species Act of 1973, as amended (ESA), and the Lacey Act Amendments of 1981, as amended, that... INFORMATION: Background The Endangered Species Act (ESA) of 1973, as amended (16 U.S.C. 1531 et seq.), was...

  9. 76 FR 64115 - Privacy Act of 1974; Privacy Act System of Records

    2011-10-17

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-092)] Privacy Act of 1974; Privacy Act... retirement of one Privacy Act system of records notice. SUMMARY: In accordance with the Privacy Act of 1974, NASA is giving notice that it proposes to cancel the following Privacy Act system of records notice...

  10. The Pathology Laboratory Act 2007 explained.

    Looi, Lai-Meng

    2008-06-01

    laboratory practices are left to be specified by the Director-General of Health, providing for a formal recognition process and room for revision as pathology practices evolve. Encompassed in the responsibilities of the licensee is the requirement that samples are received and results issued through, and management vested in, a registered medical or dental practitioner. This effectively prohibits "walk-ins" to the laboratory and indiscriminate public screening. The requirement for a person-in-charge in accordance with class and speciality of laboratory ensures that the laboratory is under the charge of the pathology profession. Examined carefully, the requirements of the Act are similar to laboratory accreditation, but are backed by legislation. Many of these details will be spelt out in the Regulations, and these in turn are likely to fall back on National professional guidelines, as accreditation does. Although not at first obvious, enforcement of the Act is based on self-regulation by pathology laboratory professionals. Sincere professional input is thus required to embrace its philosophy, ensure rational and transparent enforcement of legislation, and develop National guidelines for good pathology practices upon which enforcement may be based.

  11. 75 FR 12377 - Native American Graves Protection and Repatriation Act Regulations-Disposition of Culturally...

    2010-03-15

    ... support of a particular religious point of view or excessive entanglement with religion in the context of... Religious Freedom Act. Our Response: The proposed change revised the regulatory definition of cultural... Freedom Act. Section 10.2(e)(2) Definition of Culturally Unidentifiable Section 10.2(e)(2) defines the...

  12. 78 FR 63892 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    2013-10-25

    .../13monkeia.html . Copies of the small entity compliance guide are available at the following internet address... Procedure Act (APA). Pursuant to section 305(c)(3)(B) of the Magnuson-Stevens Act, management measures... APA. Comments and Responses Fifteen comments were received during the public comment period on the...

  13. 78 FR 1251 - Notice of Lodging of Proposed Consent Decree Under the Oil Pollution Act

    2013-01-08

    ... DEPARTMENT OF JUSTICE Notice of Lodging of Proposed Consent Decree Under the Oil Pollution Act On December 21, 2012, the Department of Justice lodged a proposed consent decree with the United States... Oil Pollution Act, 33 U.S.C. 2702, 2706, and Section 128D of the Hawaii Environmental Response law...

  14. Long-acting reversible contraceptive acceptability and unintended pregnancy among women presenting for short-acting methods: a randomized patient preference trial.

    Hubacher, David; Spector, Hannah; Monteith, Charles; Chen, Pai-Lien; Hart, Catherine

    2017-02-01

    Measures of contraceptive effectiveness combine technology and user-related factors. Observational studies show higher effectiveness of long-acting reversible contraception compared with short-acting reversible contraception. Women who choose long-acting reversible contraception may differ in key ways from women who choose short-acting reversible contraception, and it may be these differences that are responsible for the high effectiveness of long-acting reversible contraception. Wider use of long-acting reversible contraception is recommended, but scientific evidence of acceptability and successful use is lacking in a population that typically opts for short-acting methods. The objective of the study was to reduce bias in measuring contraceptive effectiveness and better isolate the independent role that long-acting reversible contraception has in preventing unintended pregnancy relative to short-acting reversible contraception. We conducted a partially randomized patient preference trial and recruited women aged 18-29 years who were seeking a short-acting method (pills or injectable). Participants who agreed to randomization were assigned to 1 of 2 categories: long-acting reversible contraception or short-acting reversible contraception. Women who declined randomization but agreed to follow-up in the observational cohort chose their preferred method. Under randomization, participants chose a specific method in the category and received it for free, whereas participants in the preference cohort paid for the contraception in their usual fashion. Participants were followed up prospectively to measure primary outcomes of method continuation and unintended pregnancy at 12 months. Kaplan-Meier techniques were used to estimate method continuation probabilities. Intent-to-treat principles were applied after method initiation for comparing incidence of unintended pregnancy. We also measured acceptability in terms of level of happiness with the products. Of the 916

  15. 76 FR 4436 - Privacy Act of 1974; Report of Modified or Altered System of Records

    2011-01-25

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Privacy Act of... following Breach Response Routine Use Language to comply with the Office of Management and Budget [[Page 4437

  16. 77 FR 38363 - Office of Privacy, Records, and Disclosure; Privacy Act of 1974, as Amended

    2012-06-27

    ... delinquencies; final determinations of appeals; name/ title of officials responsible for denial of records; and... FOIA and the Privacy Act. Also used to produce statistical reports; and as a data source for management...

  17. 75 FR 9158 - Atlantic Coastal Fisheries Cooperative Management Act Provisions; Coastal Sharks Fishery

    2010-03-01

    ... Coastal Fisheries Cooperative Management Act Provisions; Coastal Sharks Fishery AGENCY: National Marine... Commission's Interstate Fishery Management Plan (ISFMP) for Coastal Sharks. Subsequently, the Commission... New Jersey failed to carry out its responsibilities under the Coastal Sharks ISFMP, and if the...

  18. On being responsible

    Davies, Sarah Rachael; Glerup, Cecilie; Horst, Maja

    2014-01-01

    as to enable innovation. To call for responsibility has, indeed, become somewhat trite. In this essay we take not the normative demand for responsibility, but its operationalisation, as our analytical focus, arguing that it is important not to underestimate the term’s practical flexibility and discursive...... multiplicity. To illustrate this point we consider firstly the range of ways in which ‘responsibility’ is articulated within the literature on higher education and sociology of science; and, secondly, how notions of responsible development are understood, and acted upon, in two different US sites: an academic...

  19. Modification as a propositional act

    Rijkhoff, Jan

    2014-01-01

    A complete functional theory of grammar should be able to specify the communicative function of each constituent in a sentence (or rather ‘Discourse Act’). Whereas predicating and referring have been given due attention in functional approaches to grammar, the modifying function of linguistic...... material in a Discourse Act has been largely ignored. This chapter argues (i) that modifying is no less actional than predicating or referring in the process of verbal communication and (ii) that the modifying function of linguistic material should be specified at the highest level of representation...

  20. The European Model Company Act

    Cleff, Evelyne Beatrix

    2011-01-01

    European Company Law regulation is currently undergoing a reform. These reforms raise a number of regulatory questions, such as what should be the aims of companies' legislation, and how these aims should best be met by regulation. Many of the reforms and discussions (both on EU and national level...... an increasing influence on the framing of company legislation, such as the choice between mandatory or default rules. This article introduces the project 'European Company Law and the choice of Regulatory Method' which is carried out in collaboration with the 'European Model Company Act Group'. The project aims...

  1. 77 FR 39749 - Sunshine Act Meeting

    2012-07-05

    ... advertising in securities offerings conducted pursuant to Rule 506 of Regulation D under the Securities Act... Startups Act. At times, changes in Commission priorities require alterations in the scheduling of meeting...

  2. 75 FR 11565 - Sunshine Act Meetings

    2010-03-11

    ... NATIONAL COUNCIL ON DISABILITY Sunshine Act Meetings Type: Quarterly Meeting. Dates and Times.... Agenda: Public Comment Sessions; Emergency Management; Developmental Disabilities and Bill of Rights Act, International Development, National Summit on Disability Policy 2010, United States Marine Corps Research...

  3. Clean Water Act Section 404 and Agriculture

    The U.S. Department of Agriculture (USDA) and EPA have longstanding programs to promote water quality and broader environmental goals identified in both the Agriculture Act of 2014 and the Clean Water Act.

  4. 7 CFR 1209.1 - Act.

    2010-01-01

    ... the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE MUSHROOM PROMOTION, RESEARCH, AND CONSUMER INFORMATION ORDER Mushroom Promotion, Research, and Consumer Information Order Definitions § 1209.1 Act. Act...

  5. 7 CFR 1215.1 - Act.

    2010-01-01

    ... the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POPCORN PROMOTION, RESEARCH, AND CONSUMER INFORMATION Popcorn Promotion, Research, and Consumer Information Order Definitions § 1215.1 Act. Act means...

  6. 7 CFR 1230.1 - Act.

    2010-01-01

    ... the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PORK PROMOTION, RESEARCH, AND CONSUMER INFORMATION Pork Promotion, Research, and Consumer Information Order Definitions § 1230.1 Act. Act means the...

  7. Nuclear liability and the Price--Anderson Act

    Wilson, R.

    1977-01-01

    The Price-Anderson Act is viewed as meeting public needs in a unique and responsible way, reflecting the far-sightedness of those involved in the early development of nuclear power who saw the importance of building safety into each step of the program. An extension of the Act is advised as a first step in recognizing that many potential and real disasters (e.g., dam breaks, floods, etc.) are man-made rather than ''Acts of God''. Rather than abolish the Price-Anderson Act because it is unique, the case is made for extending it to cover these other situations. Provisions of the Act are examined in terms of the role of negligence in nuclear accidents, and the conclusion is reached that public concern for reactor safety should not be affected. Limited assets on the part of insurers and insurance pools have made government involvement important but not a real subsidy because of high premiums. Premiums in the new amendment are paid retroactively when there is an accident, which relieves the problem of anticipating what premiums may be needed in the future. This limits government liability and, combined with the waiver of defenses against liability, offers better protection for the public. Recommendations for allowing tort law to operate above the $560 million Price-Anderson limits are criticized, and a counter proposal is made for reassessing the figure at an appropriate limit and extending insurance to competitive industries

  8. 34 CFR 5.1 - Act.

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Act. 5.1 Section 5.1 Education Office of the Secretary...-10) Definitions § 5.1 Act. As used in this part, Act means section 552 of title 5, United States Code, as amended by Pub. L. 90-23, codifying the Act of July 4, 1966, sometimes referred to as the “Freedom...

  9. 7 CFR 1205.10 - Act.

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Act. 1205.10 Section 1205.10 Agriculture Regulations... for Conduct of Sign-up Period Definitions § 1205.10 Act. The term Act means the Cotton Research and Promotion Act, as amended [7 U.S.C 2101-2118; Public Law 89-502, 80 Stat 279, as amended]. ...

  10. 12 CFR 268.203 - Rehabilitation Act.

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Rehabilitation Act. 268.203 Section 268.203... Rehabilitation Act. (a) Model employer. The Board shall be a model employer of individuals with disabilities. The... Rehabilitation Act of 1973, as amended (29 U.S.C. 791), has been violated in a complaint alleging nonaffirmative...

  11. 29 CFR 1614.203 - Rehabilitation Act.

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Rehabilitation Act. 1614.203 Section 1614.203 Labor... EMPLOYMENT OPPORTUNITY Provisions Applicable to Particular Complaints § 1614.203 Rehabilitation Act. (a... Rehabilitation Act of 1973, as amended (29 U.S.C. 791), has been violated in a complaint alleging nonaffirmative...

  12. 12 CFR 619.9000 - The Act.

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false The Act. 619.9000 Section 619.9000 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM DEFINITIONS § 619.9000 The Act. The Farm Credit Act of 1971; Pub. L. 92-181 and amendments. ...

  13. 7 CFR 29.13 - The act.

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false The act. 29.13 Section 29.13 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... INSPECTION Regulations Definitions § 29.13 The act. The Tobacco Inspection Act, approved August 23, 1935. (7...

  14. 3 CFR - The Endangered Species Act

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false The Endangered Species Act Presidential Documents Other Presidential Documents Memorandum of March 3, 2009 The Endangered Species Act Memorandum for the Heads of Executive Departments and Agencies The Endangered Species Act (ESA), 16 U.S.C. 1531 et seq...

  15. Allegheny County Clean Indoor Air Act Exemptions

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — List and location of all the businesses and social clubs who have received an exemption from the Pennsylvania Clean Indoor Air Act. “The Clean Indoor Air Act, Act...

  16. 76 FR 77558 - Sunshine Act Meeting; Notice

    2011-12-13

    ... LEGAL SERVICES CORPORATION Sunshine Act Meeting; Notice DATES: Date and Time: The Legal Services Corporation's Operations & Regulations Committee will meet December 16, 2011. The meeting will commence at 4 p... Bylaws necessitated by the DC Nonprofit Corporation Act of 2010. 3. Public comment. 4. Consider and act...

  17. 31 CFR 0.216 - Privacy Act.

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Privacy Act. 0.216 Section 0.216... RULES OF CONDUCT Rules of Conduct § 0.216 Privacy Act. Employees involved in the design, development, operation, or maintenance of any system of records or in maintaining records subject to the Privacy Act of...

  18. Rates of sustained virological response 12 weeks after the scheduled end of direct-acting antiviral (DAA)-based hepatitis C virus (HCV) therapy from the National German HCV registry: does HIV coinfection impair the response to DAA combination therapy?

    Bischoff, J; Mauss, S; Cordes, C; Lutz, T; Scholten, S; Moll, A; Jäger, H; Cornberg, M; Manns, M P; Baumgarten, A; Rockstroh, J K

    2018-04-01

    The European Association for the Study of the Liver (EASL) treatment recommendations for hepatitis C no longer discriminate between HIV/hepatitis C virus (HCV)-coinfected and HCV-monoinfected patients. However, recent data from Spain are questioning these recommendations on the basis of the findings of higher relapse rates and lower cure rates in HIV/HCV-infected subjects. The aim of our study was to compare HCV cure rates in monoinfected and coinfected patients from Germany. Data acquired from the Deutsches Hepatitis C-Registry were analysed. A total of 5657 HCV-monoinfected subjects and 488 HIV/HCV-coinfected patients were included in the study. Rates of sustained virological response 12 weeks after the scheduled end of therapy (SVR12) were collected in both subgroups and in cirrhotic and noncirrhotic patients. HIV/HCV-coinfected patients were more frequently male (84.6% vs. 56.4%, respectively; P  350 cells/μL in 63.1% of HIV-positive subjects and 88.7% were on antiretroviral therapy. SVR12 rates were 90.3% (5111 of 5657) in our HCV-monoinfected cohort and 91.2% (445 of 488) in our coinfected patients. Liver cirrhosis was confirmed in 1667 of 5657 (29.5%) monoinfected patients and 84 of 488 (17.2%; P < 0.001) coinfected patients. SVR12 rates did not differ between HCV-monoinfected and HIV/HCV-coinfected patients with liver cirrhosis (87.8% vs. 89.3%, respectively; P = 0.864). A treatment duration of 8 weeks did not reduce the percentage of patients with SVR12 in either subgroup (93.7% in both groups). We found high SVR12 rates in monoinfected as well as coinfected individuals. No differences were detected between the two subgroups regardless of whether there was accompanying liver cirrhosis or a shortened treatment duration. © 2018 British HIV Association.

  19. Review of the nuclear liability act

    1990-01-01

    There has always been concern that nuclear materials have the potential to cause injury and property damage. For this reason, nuclear operators have always been required by national regulatory authorities to exercise special precautions in the operation of their facilities. Federal legislation was drafted in Canada as the Nuclear Liability Act in 1970. The Act ensures that funds are available from all operators of nuclear facilities to provide financial compensation to third parties for injuries or damages suffered as a result of a nuclear incident; at the same time the Act provides protection to the operators by limiting their related liability. The Act also protects persons other than operators. The review of the Act has progressed in stages. The first stage was conducted by the staff of the Atomic Energy Control Board and catalogued previously identified difficulties with the Act. The second stage was a preliminary examination of the Act by an Interdepartmental Working Group. 2 figs

  20. Learning activism, acting with phronesis

    Lee, Yew-Jin

    2015-12-01

    The article "Socio-political development of private school children mobilising for disadvantaged others" by Darren Hoeg, Natalie Lemelin, and Lawrence Bencze described a language-learning curriculum that drew on elements of Socioscientific issues and Science, Technology, Society and Environment. Results showed that with a number of enabling factors acting in concert, learning about and engagement in practical action for social justice and equity are possible. An alternative but highly compatible framework is now introduced—phronetic social research—as an action-oriented, wisdom-seeking research stance for the social sciences. By so doing, it is hoped that forms of phronetic social research can gain wider currency among those that promote activism as one of many valued outcomes of an education in science.

  1. Lithuania’s Balancing Act

    Šlekys Deividas

    2017-12-01

    Full Text Available Since regaining independence in 1990 and creating its regular armed forces, Lithuania has had to do a balancing act. It has had to balance between different approaches of state defence, military structure, collective and national defence. Due to events in Ukraine Lithuania had to reconfigure this balance. The Russian threat forced to emphasize strategy of territorial defence, which altogether required tying up forces and enlarging its numbers by bringing back conscription, substantially increased defence budget, followed by higher tempo and scale in procurement and training. However, Lithuania has managed to maintain its activity and participation in international military operations and political initiatives. Its recent contributions have led to an assumption that its participation in various military missions in the future will not diminish, quite the opposite. Increasing the framework of cooperation in terms of defence and security initiatives will involve Lithuania more deeply and will require further contributions.

  2. Personal Information as Communicative Acts

    Mai, Jens-Erik

    2016-01-01

    The paper extends previous accounts of informational privacy as a contextual notion. Where previous accounts have focused on interpretations of the privacy context itself as being contextual and open for negotiation and interpretation, this paper extends those analyses and shows that personal...... information itself is in fact best understood as contextual and situational—and as such open for interpretation. The paper reviews the notion of information as it has been applied in informational privacy and philosophy of information, and suggests that personal information ought to be regarded...... as communicative acts. The paper suggests a reconceptualization of informational privacy from having its focus on controlling, limiting, and restricting access to material carriers of information to a focus on a regulation of the use, analysis, and interpretation of personal information....

  3. ACT Reporting Category Interpretation Guide: Version 1.0. ACT Working Paper 2016 (05)

    Powers, Sonya; Li, Dongmei; Suh, Hongwook; Harris, Deborah J.

    2016-01-01

    ACT reporting categories and ACT Readiness Ranges are new features added to the ACT score reports starting in fall 2016. For each reporting category, the number correct score, the maximum points possible, the percent correct, and the ACT Readiness Range, along with an indicator of whether the reporting category score falls within the Readiness…

  4. 77 FR 15555 - Freedom of Information Act and Privacy Act Procedures

    2012-03-16

    ... Freedom of Information Act and Privacy Act Procedures AGENCY: Special Inspector General for Afghanistan... Freedom of Information Act (FOIA) and the Privacy Act of 1974. These procedures will facilitate public..., Freedom of information, Privacy. Authority and Issuance For the reasons set forth above, SIGAR establishes...

  5. 75 FR 36535 - Freedom of Information Act, Privacy Act of 1974; Implementation

    2010-06-28

    ... DEPARTMENT OF THE TREASURY Office of the Secretary 31 CFR Part 1 Freedom of Information Act... Freedom of Information Act (FOIA) and its regulations concerning the Privacy Act of 1974 (Privacy Act). It... correct those errors. List of Subjects in 31 CFR Part 1 Freedom of Information; Privacy. 0 Accordingly...

  6. 13 CFR 107.115 - 1940 Act and 1980 Act Companies.

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false 1940 Act and 1980 Act Companies. 107.115 Section 107.115 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS... Companies. A 1940 Act or 1980 Act Company is eligible to apply for an SBIC license, and an existing Licensee...

  7. 75 FR 81205 - Privacy Act: Revision of Privacy Act Systems of Records

    2010-12-27

    ... DEPARTMENT OF AGRICULTURE Office of the Secretary Privacy Act: Revision of Privacy Act Systems of Records AGENCY: Office of the Secretary, USDA. ACTION: Notice to Revise Privacy Act Systems of Records... two Privacy Act Systems of Records entitled ``Information on Persons Disqualified from the...

  8. 76 FR 67763 - Privacy Act of 1974; Privacy Act System of Records

    2011-11-02

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-109)] Privacy Act of 1974; Privacy Act... proposed revisions to an existing Privacy Act system of records. SUMMARY: Pursuant to the provisions of the Privacy Act of 1974 (5 U.S.C. 552a), the National Aeronautics and Space Administration is issuing public...

  9. 76 FR 64114 - Privacy Act of 1974; Privacy Act System of Records

    2011-10-17

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-093)] Privacy Act of 1974; Privacy Act... proposed revisions to an existing Privacy Act system of records. SUMMARY: Pursuant to the provisions of the Privacy Act of 1974 (5 U.S.C. 552a), the National Aeronautics and Space Administration is issuing public...

  10. 76 FR 64112 - Privacy Act of 1974; Privacy Act System of Records Appendices

    2011-10-17

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-091)] Privacy Act of 1974; Privacy Act...: Revisions of NASA Appendices to Privacy Act System of Records. SUMMARY: Notice is hereby given that NASA is... Privacy Act of 1974. This notice publishes those amendments as set forth below under the caption...

  11. 78 FR 40515 - Privacy Act of 1974; Privacy Act System of Records

    2013-07-05

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 13-071] Privacy Act of 1974; Privacy Act System of Records AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of Privacy Act system of records. SUMMARY: Each Federal agency is required by the Privacy Act of 1974 to publish...

  12. 78 FR 77503 - Privacy Act of 1974; Privacy Act System of Records

    2013-12-23

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 13-149] Privacy Act of 1974; Privacy Act... proposed revisions to existing Privacy Act systems of records. SUMMARY: Pursuant to the provisions of the Privacy Act of 1974 (5 U.S.C. 552a), the National Aeronautics and Space Administration is issuing public...

  13. 77 FR 69898 - Privacy Act of 1974; Privacy Act System of Records

    2012-11-21

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 12-100] Privacy Act of 1974; Privacy Act... proposed revisions to an existing Privacy Act system of records. SUMMARY: Pursuant to the provisions of the Privacy Act of 1974 (5 U.S.C. 552a), the National Aeronautics and Space Administration is issuing public...

  14. Acting Antarctica: science on stage

    Ciceri, Piera; Tizzoni, Paola; Pierro, Luigia

    2016-04-01

    Key-words: Polar science, Earth science, Theatre, Hands on activities The legendary Antarctic Expedition of sir E. Shackleton and his crew of 27 aboard the Endurance (1914/16) trapped in the Antarctic ice has become the starting point to learn about Polar Science and Climate Change. While the students were involved into this incredible adventure by the astonishing images of the Australian photographer Frank Hurley (who joined the crew), they discovered the world in which this story happened. Students were then involved in hands-on activities and role plays and have become the writers of the play "Uomini a scienza ai confini del mondo". They act the story of Shackelton's expedition and they tell at the same time to the audience about ice pack, ice cores and their role in understanding the past of the climate, physical and geographical characteristic of polar regions, thermal phenomena related to adaptations of polar animals, solar radiation at different latitude, day/night duration. The theater was the place to "stage" some scientific experiments and to explain the current research carried out in polar regions and their importance in climate change studies and to stress some similarities between Antarctica and space. The project was carried out from teachers of science, letters and geography and was born in collaboration with the "Piccolo Teatro di Milano" and the association "Science Under 18" with the support of a professional actor and director and was played for other schools at "EXPO 2015" in Milano (Italy). In our opinion drama activities improve reading comprehension, and both verbal and non-verbal communication skills. To be able to write and to act, students need a deep understanding of contents. Arts, including theatre, are a good key to involve emotionally students. To have an audience different from their own teachers and classmates offers a real task and the opportunity to play and let grow real skills.

  15. Responsibility and Responsiveness

    Nissen, Ulrik Becker

    2011-01-01

    The debate on the role and identity of Christian social ethics in liberal democracy touches upon the question about the relationship between universality and speci-ficity. Rather than argue for the difference between these approaches, it can be argued that they are to be understood in a different......The debate on the role and identity of Christian social ethics in liberal democracy touches upon the question about the relationship between universality and speci-ficity. Rather than argue for the difference between these approaches, it can be argued that they are to be understood...... contemporary positions of communicative ethics, H. Richard Niebuhr’s understanding of responsibility as responsiveness, and Dietrich Bonhoeffer’s Christological concept of responsibility in a constructive dialogue with each other, the article has attempted to outline main tenets of a responsive concept...

  16. Act of 14 July 1983 amending Act of 29 March 1958 relating to the protection of the population against the hazards of ionizing radiation

    1983-01-01

    The Act of 29 March 1958 on protection of the population against the hazards of ionizing radiation has been amended by an Act of 14 July 1983. The amendments concern, in particular, the non-involvement of communal authorities in decisions taken under the Act, the inclusion of the concept of the environment as a complement to public safety, and the extension of the powers of officials responsible for supervising certain aspects of the transport of radioactive materials. Finally, a new Section has been added which empowers the King to suspend or cancel decisions by decentralised administrations which affect the transport of nuclear substances. (NEA) [fr

  17. THE USE OF OFFICIAL LANGUAGES ACT: DIVERSITY AFFIRMED?

    JL (Loot Pretorius

    2013-04-01

    Full Text Available SUMMARYA full sixteen years after the coming into force of the 1996 Constitution, Parliament responded to the constitutional obligation to regulate and monitor, by legislative and other means, the use of official languages by adopting the Use of Official Languages Act 12 of 2012. The Act represents a very limited normative appreciation of this constitutional instruction. The official language clause of the Constitution expresses a normative commitment regarding the positive affirmation of linguistic diversity, which is directly informed by and closely aligned to the core normative values of the Constitution. The Constitution’s positive evaluation of difference, including linguistic difference, inter alia, flows from the values of substantive equality, equal citizenship, dignity and proportionality. However, the way in which the Act institutionalises the promotion of inclusive linguistic diversity does not reflect an unambiguous recognition of this obligation being normatively embedded in the foundational value structure of the Constitution. The real responsibility for decisions regarding official language use is located in the policy-making competence of non-independent administrative bodies. The Act itself is devoid of instructive standards of its own to guide administrative decision-making regarding official language use. This results in the responsibility for making the most important normative choices regarding the use of official languages not being reserved for the legislative process, but entrusted to non-independent advisory administrative bodies. The nature of the Act confirms that it never was the intention of the government to be bound by legislation in this respect. This modus operandi is democratically deficient and compromises both the separation of powers and the principle of legal certainty as fundamental tenets of the rule of law.

  18. 75 FR 33608 - Privacy Act of 1974; System of Records

    2010-06-14

    ...In accordance with the Privacy Act of 1974, as amended (Privacy Act), the Department of Education (Department) publishes this notice proposing to revise the system of records notice for the Investigative Files of the Inspector General (18-10-01), 68 FR 38154 (June 26, 2003). The Department proposes to amend this system of records notice by: (1) Adding a new routine use to allow reporting on the activities of the Inspector General regarding American Recovery and Reinvestment Act funds to the Recovery Accountability and Transparency Board (RATB) as established by the American Recovery and Reinvestment Act of 2009 (Pub. L. 111-5); (2) adding a new routine use to allow for disclosure of information in connection with response and remedial efforts in the event of a data breach in accordance with Office of Management and Budget (OMB) requirements in M-07-16 (May 22, 2007); (3) revising routine uses ``(12) Disclosure to the President's Council on Integrity and Efficiency'' and ``(13) Disclosure for Qualitative Assessment Reviews'' to allow reporting on the activities of the Inspector General to the Council of Inspectors General on Integrity and Efficiency (formerly the President's Council on Integrity and Efficiency) as established by the Inspector General Reform Act of 2008 (Pub. L. 110-409); (4) revising the routine use ``(4) Disclosure to Public and Private Sources in Connection with the Higher Education Act of 1965, as Amended (HEA)'' to allow the disclosure of information to an educational institution or a school that is or was a party to an agreement with the Secretary of Education pursuant to the HEA; and (5) updating the system location addresses. This system of records provides essential support for investigative activities of the Office of Inspector General (OIG) relating to the Department's programs and operations, enabling the OIG to secure and maintain the necessary information and to coordinate with other law enforcement agencies as appropriate.

  19. The social act of electronic medication prescribing.

    Aarts, Jos

    2013-01-01

    Prescribing medication is embedded in social norms and cultures. In modern Western health care professionals and policy makers have attempted to rationalize medicine by addressing cost-effectiveness of diagnostic and therapeutic treatments and the development of guidelines and protocols based on the outcomes of clinical studies. These notions of cost-effectiveness and evidence-based medicine have also been embedded in technology such as electronic prescribing systems. Such constraining systems may clash with the reality of clinical practice, where formal boundaries of responsibility and authorization are often blurred. Such systems may therefore even impede patient care. Medication is seen as the essence of medical practice. Prescribing is a social act. In a hospital medications may be aimed at treating a patient for a specific condition, in primary care the professional often meets the patient with her or his social and cultural notions of a health problem. The author argues that the design and implementation of electronic prescribing systems should address the social and cultural context of prescribing. Especially in primary care, where health problems are often ill defined and evidence-based medicine guidelines do not always work as intended, studies need to take into account the sociotechnical character of electronic prescribing systems.

  20. Business judgement rule in Czech Corporations Act

    Jaromír KOŽIAK

    2013-12-01

    Full Text Available Czech private law is currently undergoing a thorough transformation. This inclundes adoption of a brand new Corporations Act, which is to supersede the current Commercial Code. The new legislation introduces several new rules governing liability of company executive officers. One of these is business judgment rule. It should provide company executive officers with a certain level of protection against litigantion – if specific terms are met, it is presumed, that they carried out their responsibilities with proper care. I intend to demonstrate, that the czech business judgment rule is flawed, despite the fact that it draws from foreign examples and that this regulation, although seemingly groundbreaking, in fact changes nothing in examination of the decisions of the company executive officers in Czech Republic. The main goal of this article is therefore to analyze and criticize the business judgment rule in the new Czech legislation and to compare it to notable foreign legal systems. The methods used are inductive and deductive reasoning, author‘s own analysis of legal text, comparative method and compilation of available resources relating to the topic of the article.

  1. Local policies for DSM: the UK's home energy conservation act

    Jones, E.; Leach, M.

    2000-01-01

    Residential energy use accounts for approximately 28 per cent of total primary energy use in the UK, with consumption in this sector forecast to increase due partly to expanding numbers of households. Finding ways to reduce residential energy consumption must form a key part of the climate change strategies of the UK and all developed countries. In 1995, an innovative piece of legislation was passed in the UK, devolving residential energy efficiency responsibility to local government. Under 'The Home Energy Conservation Act' (HECA), local authorities are obliged to consider the energy efficiency of private as well as public housing stock. Authorities were given a duty to produce a strategy for improving residential energy efficiency in their area by 30 per cent in the next 10-15 years. This paper describes the enormous variation in the quality of local authorities' strategies and discusses reasons for this variation. Based on a nationwide survey of HECA lead officers, it considers the opportunities and constraints facing local authorities, and what has been achieved to-date under the Act. It also examines how HECA fits into the UK's national energy policy and explains the roles of other institutions across the public, private and voluntary sector in facilitating implementation of the Act. Finally, the paper considers how other countries can learn from the UK's HECA experience and can use the Act as a template to apply the principle of subsidiarity to this area of environmental policy. (Author)

  2. 75 FR 39669 - Privacy Act of 1974; System of Records

    2010-07-12

    ...In accordance with the Privacy Act of 1974, as amended (Privacy Act), the Department of Education (Department) publishes this notice proposing to revise the system of records notice for the Hotline Complaint Files of the Inspector General (18-10-04), 64 FR 30157-59 (June 4, 1999). The Department proposes to amend this system of records notice by: (1) Adding that a purpose of the system is to report on complaints and allegations related to American Recovery and Reinvestment Act of 2009 (ARRA) funds to the Recovery Accountability and Transparency Board (RATB) as established by the ARRA (Pub. L. 111- 5); (2) adding a new routine use to allow the disclosure of ARRA- related complaints and allegations to the RATB; (3) adding a new routine use to allow for disclosure of information in connection with response and remedial efforts in the event of a data breach in accordance with Office of Management and Budget (OMB) requirements in M-07-16 (May 22, 2007); (4) revising the routine use ``Disclosure to Public and Private Sources in Connection with the Higher Education Act of 1965, as amended (HEA)'' to allow the disclosure of information to an educational institution or a school that is or was a party to an agreement with the Secretary of Education pursuant to the HEA; and (5) updating the address of the System Manager.

  3. Radioactive Substances Act, 1957, No 5

    1982-01-01

    This Act as amended regulates the possession, sale and use of radioactive materials and irradiating apparatus. It sets up a Radiological Advisory Council to advise the competent authorities on questions within the scope of the Act, also with a view to radiation protection. The Council's rules of procedure are laid down. The Act also provides that, subject to prescribed exemptions, no person may hold, use or sell radioactive materials without a licence. (NEA) [fr

  4. New electricity act brings in private sector

    Anon.

    1995-01-01

    Opening up the State's electricity industry, previously the domain of the former Queensland Electricity Commission (QEC), is part of an overall restructuring of the industry under the new Queensland Electricity Act. Under this Act, the QEC was split into generating and transmission and supply corporations. The Act provides for the regulation of the electricity industry and the regulation of the use of electricity and safety in relation to the supply and use of electricity.(Author). 6 photos

  5. Radiological Protection Miscellaneous Provisions Act 2014

    Irish Legislation

    2014-07-01

    This Act provides for the dissolution of the Radiological Protection Institute of Ireland and the transfer of all its functions, assets, liabilities and staff to the Environmental Protection Agency, to give effect to the Amendment to the Convention on the Physical Protection of Nuclear Material done at Vienna on 8 July 2005, to amend the Radiological Protection Act 1991, the Environmental Protection Agency Act 1992 and certain other enactments, and to provide for matters connected therewith

  6. Believing responsibly : intellectual obligations and doxastic excuses

    Peels, H.D.|info:eu-repo/dai/nl/31393374X

    2012-01-01

    What we believe and what we do not believe has a great impact on what we do and fail to do. Hence, if we want to act responsibly, we should believe responsibly. However, do we have the kind of control over our beliefs that such responsibility for our beliefs seems to require? If not, can we maybe

  7. Resource Conservation and Recovery Act Information (RCRAInfo)

    U.S. Environmental Protection Agency — The Resource Conservation and Recovery Act Information (RCRAInfo) system contains information reported to the state environmental programs on activities and cleanup...

  8. BBG 2009 Freedom of Information Act Repot

    Broadcasting Board of Governors — The Broadcasting Board of Governors' annual Freedom of Information Act (FOIA) report includes detailed statistics on the number and disposition of FOIA requests,...

  9. BBG 2008 Freedom of Information Act Report

    Broadcasting Board of Governors — The Broadcasting Board of Governors' annual Freedom of Information Act (FOIA) report includes detailed statistics on the number and disposition of FOIA requests,...

  10. Motivating administrative acts - doctrinal and jurisprudential issues

    Mihai Cristian APOSTOLACHE

    2014-06-01

    Full Text Available The article approaches the topic of administrative acts motivation, analyzed from the doctrinal and jurisprudential perspective. If at first, motivation was considered merely a formal condition of the administrative act, as a result of the national and European, doctrinal and jurisprudential evolution, motivation is now regarded as one of the most important conditions of validity for the administrative act. Motivating administrative acts represents also a manifestation of the right to information, sealed by the Romanian Constitution, and a dimension of the right to a good administration, as stipulated in the Charter of Fundamental Rights of the European Union.

  11. Federal Technology Transfer Act Success Stories

    Successful Federal Technology Transfer Act (FTTA) partnerships demonstrate the many advantages of technology transfer and collaboration. EPA and partner organizations create valuable and applicable technologies for the marketplace.

  12. 76 FR 70131 - Sunshine Act Notice

    2011-11-10

    ... Age Under the Age Discrimination in Employment Act, and 3. Overcoming Barriers to the Employment of... EEOC provides sign language interpretation and Communication Access Realtime Translation (CART...

  13. The Education Act (Ontario) 1980: A Review.

    Hodder, C. J.

    1984-01-01

    Ontario has provided special education legislation through the Education Amendment Act, 1980. Issues related to teacher preparation for special education and program planning and implementation are reviewed. (DF)

  14. Atomic Energy Amendment Act 1978, No. 31

    1978-01-01

    This Act amends certain Sections of the Atomic Energy Act 1953. The principal modifications concern the definitions of atomic energy, prescribed substances, the provision and supply of uranium in relation to the functions of the Atomic Energy Commission, compliance with the agreement with the IAEA on the application of safeguards under the Non-Proliferation Treaty as well as with any agreement with any other international organization or another country. The Act also amends the 1953 Act in respect of the control of prescribed substances and repeals the section concerning jurisdiction of courts. (NEA) [fr

  15. Naturalistic Observations of Nonverbal Children with Autism: A Study of Intentional Communicative Acts in the Classroom

    Samantha Drain

    2013-01-01

    Full Text Available We examined evoked and spontaneous communicative acts in six nonverbal children with autism (10–15 years, M = 12.8, SD = 2.1. All participants attended the same special school for children with autism but were in different classes. Each was observed for 30 minutes during a typical school day. An observer coded the presence/absence of an antecedent, the form and function of the communicative act, and the teacher’s response to the child. One hundred and fifty-five communicative acts were observed, 41% were spontaneous and 59% were evoked. The main antecedents to evoked communicative acts were verbal prompts, and most of the evoked communicative acts were physical in nature (i.e., motor acts and gestures. However, verbalizations and the use of the Picture Exchange Communication System (PECS were higher for spontaneous communicative acts. The functions of spontaneous communicative acts were primarily requests. Results showed a substantial number of “nonresponses” from teachers, even following evoked communicative acts. These results suggest that teachers may not actively promote intentional communication as much as possible. Therefore, our findings provide information concerning ways in which educators could facilitate intentional communication in non-verbal children with autism.

  16. Corporate social responsibility and customer behaviour, empirical ...

    pc

    2018-03-05

    Mar 5, 2018 ... responsible consumption, business ethics, relationship marketing. ... system and commercial practices adopted by businesses. Customers are showing their .... includes all the situations where the purchasing act takes into.

  17. Legal Issues of A Surrogacy Contract Based on Iranian Acts

    Amir Pirouz

    2011-06-01

    Full Text Available Assistive technologies have always opened new horizons in human's life, posed solutions to problemsand brought relief and prosperity for human beings. Iranian judicial authorities have recently recognizedthe importance of medical technologies. Accordingly, Iranian legal system has recognized surrogacy anda surrogacy contract seems unavoidable for surrogacy to be legally valid, socially acceptable andreligiously legitimate. As a legal defense of including a typical surrogacy contract in contract law, thisreview studies the four building blocks of a valid contract: the intention and consent of parties, theirlegal capacity, the subject of the contract and its legitimacy. Discussing related Iranian Acts concerningcontracts and responsibilities of parties, the authors of the present article deal with main commitmentsand responsibilities of the parties to a typical surrogacy contract: infertile couples, surrogate, fertilityclinic or medical institute, and surrogate's husband. The authors conclude that a surrogacy contract isaccepted based on article 10 of Iranian Civil Act 1928, pose some suggestions to be included in such acontract, and emphasize that a specific Act concerning surrogacy should be approved to cover rights andlegal needs of all parties to a surrogacy contract.

  18. DANGEROUS AND HYPNOTIC DRUG ACT

    Whelan, William M.

    1961-01-01

    It is unprofessional conduct within the meaning of the Medical Practice Act to prescribe a dangerous drug without either a medical examination by a physician or other medical indications. Dangerous and hypnotic drugs are specifically defined by both state and federal law and distribution is strictly regulated. A physician may administer to his own patients such amounts of dangerous drugs as are necessary for the immediate needs of the patient. The physician may obtain such needed amounts of these drugs by an order placed with a pharmacist marked “for administration to immediate needs of patients.” A licensed physician may also prescribe dangerous and hypnotic drugs for patients and such prescriptions may be refilled on the specific authorization of the physician. A physician who dispenses dangerous and hypnotic drugs to patients must obtain a hypnotic drug license; he must use specific purchase orders when purchasing; the drugs must be labeled in the manner provided by law; and all records of sale shall be open to inspection by authorized officers of the law and kept for three years. By the Principles of Medical Ethics physicians are bound to limit the source of their professional income to medical services actually rendered. Recent decisions of the Judicial Council answer questions concerning a physician's interest in a corporation which purchases, packages and sells medicines under a corporate name. Also answered are questions as to the measures that exist to prevent physicians from abusing the privilege of owning a pharmacy, and whether a physician can ethically rent space in a building owned by him to a pharmacist with a percentage of the income of the pharmacy as rental. The public welfare of California and the nation as determined by legislation strictly regulates the distribution of dangerous drugs. It is in the best interest of the medical profession and its patients that these laws be understood and carefully observed. PMID:13784776

  19. The unity of Luke-Acts

    J. Verheyden

    1999-12-01

    Full Text Available The article contains a summary of contributions delivered at he 47th Colloquium Biblicum Lovaniense (1998 held at the Catholic University, Leuven on the subject: "The unity of Luke-Acts". The opening address was delivered by J Verheyden (Leuven on "The Unity of Luke and Acts: What are we up to?". The contributors were: J Kremer (Vienna - "Die dreifache Wiedergabe des Damaskuserlebnis Pauli in der Apostelgeschichte: Eine Hilfe für das rechte Verständnis der lukanischen Osterevangelien"; D Marguerat (Lausanne -"Jusqu' où faut-il parler d'une "unité". Luc-Actes? Continuity et ruptures dans I'ævre de Luc"; JDelobel (Leuven - "The text of Luke-Acts: A confrontation of recent theories"; R L Brawley (Chicago - "Abrahamic covenant traditions and the characterization of God in Luke-Acts"; F W Horn (Mainz - "Die Haltung des Lukas zum römischen Staat im Evangelium und in der Apostelgeschichte"; J A Fitzmyer (Washington - "The role of theSpirit in Luke-Acts"; M Rese (Munster - "The Jews in Luke-Acts: Some secondthoughts"; J Taylor (Jerusalem - "La fraction du pain en Luc-Actes"; W Radl (Augs-burg - "Die Beziehungen der Vorgeschichte zur Apostelgeschichte, dargestellt an Lk 2:22-39; F Neirynck (Leuven - "Luke 4:16-30 and the unity of Luke-Acts"; C M Tuckett (Oxford - "The Christology of Luke-Acts"; O Mainville (Montreal - "Le messianisme de Jésus: Le rapport announce/accomplissement entre Lc 1,35 et Ac 2,33"; A Lindemann (Bethel-Bielefeld - "Form und Funktion von Reden und Wundererzählungen im Lukas-evangelium und in der Apostelgeschichte", A Denaux - The theme of divine visits and human (inhospitability in Luke-Acts and its Old Testament and Graeco-Roman antecedents.

  20. Economics, Corporate Sustainability and Social Responsibility

    Tisdell, Clement A.

    2008-01-01

    It is often argued that corporate sustainability requires a corporation to make a profit, to act in a socially responsible manner and to engage in policies that are environmentally sustainable. This is sometimes called the corporation’s triple bottom line. In this paper it is argued that in practice profitability or more general maintaining economic variability constitutes a corporation’s bottom line and that it is limited by this consideration in showing social responsibility and in acting w...

  1. National Environmental Policy Act guidance: A model process

    Angle, B.M.; Lockhart, V.A.T.; Sema, B.; Tuott, L.C.; Irving, J.S.

    1995-04-01

    The ''Model National Environmental Policy Act (NEPA) Process'' includes: References to regulations, guidance documents, and plans; training programs; procedures; and computer databases. Legislative Acts and reference documents from Congress, US Department of Energy, and Lockheed Idaho Technologies Company provide the bases for conducting NEPA at the Idaho National Engineering Laboratory (INEL). Lockheed Idaho Technologies Company (LITCO) NEPA / Permitting Department, the Contractor Environmental Organization (CEO) is responsible for developing and maintaining LITCO NEPA and permitting policies, guidance, and procedures. The CEO develops procedures to conduct environmental evaluations based on NEPA, Council on Environmental Quality (CEQ) regulations, and DOE guidance. This procedure includes preparation or support of environmental checklists, categorical exclusion determinations, environmental assessment determinations, environmental assessments, and environmental impact statements. In addition, the CEO uses this information to train personnel conducting environmental evaluations at the INEL. Streamlining these procedures fosters efficient use of resources, quality documents, and better decisions on proposed actions

  2. Recovery act : states' use of highway infrastructure funds and compliance with the act's requirements.

    2009-01-01

    The American Recovery and Reinvestment Act of 2009 (Recovery Act) included more than $48 billion for the Department of Transportations (DOT) investment in transportation infrastructure, including highways, rail, and transit. This testimonybased...

  3. Atomic Energy Authority (Weapons Group) Act 1973

    1973-01-01

    This Act, which came into force on 6th March 1973 and modified Section 2 of the Atomic Energy Authority Act 1954 in respect of the Authority's power to do work on explosive nuclear devices, made provision for the transfer to the Secretary of State for Defence of the Weapons Group of the Atomic Energy Authority. (NEA) [fr

  4. Homosexual Cohabitees Act, 18 June 1987.

    1989-01-01

    The purpose of this Act is to place homosexual cohabitees in the same legal position as heterosexual cohabitees. It provides that if 2 persons are living together in a homosexual relationship, the following legal provisions relating to cohabitation shall apply to them: 1) the Cohabitees (Joint Homes) Act (1987:232), 2) the Inheritance Code, 3) the Real Property Code, 4) Chapter 10, section 9, of the Code of Judicial Procedure, 5) Chapter 4, section 19, 1st paragraph, of the Code of Execution, 6) section 19, 1st paragraph, section 35, subsection 4, and point 2a, 7th paragraph, of the regulations relating to Section 36 of the Municipal Tax Act (1928:370), 7) the Inheritance and Gift Taxes Act (1941:416), 8) Section 6 of the Court Procedures (Miscellaneous Business) Act (1946:807), 9) the Tenant Owner Act (1971:479), 10) section 10 of the Legal Aid Act (1972:429), and 11) the Notice to Unknown Creditors Act (1981:131).

  5. 76 FR 53702 - Sunshine Act Meeting

    2011-08-29

    ... concept release and request public comment on a wide range of issues under the Investment Company Act raised by the use of derivatives by investment companies regulated under that Act. Item 2: The Commission... of investment company. The second release is a concept release to solicit public comment on...

  6. 77 FR 1095 - Sunshine Act Meeting

    2012-01-09

    ... provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange... 2012 budget of the Public Company Accounting Oversight Board and will consider the related annual accounting support fee for the Board under Section 109 of the Sarbanes-Oxley Act of 2002. Commissioner...

  7. Environmental Politics and the Endangered Species Act.

    Sahr, David

    2000-01-01

    Explores the controversial issue of the Endangered Species Act (ESA) discussing the Act and the scope of the extinction problem. Reviews the arguments for and against the ESA, addresses the tactics that have been used in the political struggle over the ESA, and highlights the future of the ESA. Includes teaching activities. (CMK)

  8. 75 FR 17167 - Sunshine Act Meetings; Correction

    2010-04-05

    ... NATIONAL COUNCIL ON DISABILITY Sunshine Act Meetings; Correction AGENCY: National Council on Disability. ACTION: Notice; correction. Type: Quarterly meeting. SUMMARY: NCD published a Sunshine Act Meeting Notice in the Federal Register on March 11, 2010, notifying the public of a quarterly meeting in...

  9. 7 CFR 926.2 - Act.

    2010-01-01

    ... the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE DATA COLLECTION, REPORTING AND RECORDKEEPING REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.2 Act. Act means...

  10. Assertive Community Treatment (ACT) – metodebeskrivelse

    Benjaminsen, Lars; Kirkedal Nielsen, Ian; Møller, mikkel Stamp

    2017-01-01

    arbejde med ACT-metoden over for en målgruppe med psykiske vanskeligheder og samtidigt misbrug i en dansk kommunal kontekst. Denne manual beskriver således vigtige elementer i Assertive Community Treatment (ACT) metoden henvendt til personer med psykiske vanskeligheder og samtidigt misbrug, som det har...

  11. 76 FR 31790 - Federal Seed Act Regulations

    2011-06-02

    ... improvements in the noxious-weed seed tolerances using modern statistical applications. The AOSA has already... the introductory text. 0 B. Removing the word ``act'' and adding in its place the word ``Act'', and by...'' in paragraph (c)(2) introductory text. Sec. 201.41 [Amended] 0 6. In Sec. 201.41, paragraph (a), the...

  12. Equationally Compact Acts : Coproducts / Peeter Normak

    Normak, Peeter

    1998-01-01

    In this article equational compactness of acts and its generalizations are discussed. As equational compactness does not carry over to coproducts a slight generalization of c-equational campactness is introduced. It is proved that a coproduct of acts is c-equationally compact if and only if all components are c-equationally campact

  13. TANZANIA'S 2002 RECORDS AND ARCHIVES MANAGEMENT ACT

    However, some critical areas that need serious revisiting include supporting the Act with adequate resources, training, provisions on electronic records and records created by Union Government. The paper recommends facilitation of ample resources, training on the Act, reduction of power of director of the Records and ...

  14. The Compensation Act 2006 and School Trips

    Hunter-Jones, John

    2006-01-01

    The Compensation Act 2006 received its Royal Assent on 25 July 2006. The Act allows the courts to have regard to the social utility of "desirable activities", including school trips, in considering negligence claims. The article reviews the law of negligence as it affects teachers of the very young and considers the possible impact of…

  15. 76 FR 22939 - Sunshine Act Meeting

    2011-04-25

    ... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting Notice is hereby given, pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange... Swap,'' ``Security-Based Swap Agreement,'' the regulation of mixed swaps, and books and records...

  16. 75 FR 66811 - Sunshine Act Meeting

    2010-10-29

    ... Law 111-203, to prohibit fraud, manipulation, and deception in connection with security-based swaps. 3... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting Notice is hereby given, pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange...

  17. 75 FR 64306 - Sunshine Act Meeting Notice

    2010-10-19

    ... Transmission System. Hydro H-1 P-12107-005 Granite County, Montana. H-2 P-2496-222 Eugene Water and Electric... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Sunshine Act Meeting Notice October 14... Sunshine Act (Pub. L. 94-409), 5 U.S.C. 552b: Agency Holding Meeting: Federal Energy Regulatory Commission...

  18. 78 FR 73210 - Sunshine Act Meeting

    2013-12-05

    ... Institutional Advancement Committee will meet telephonically on December 10, 2013. The meeting will commence at... will be made of the closed session meeting of the Institutional Advancement Committee. The transcript... Americans with Disabilities Act and Section 504 of the 1973 Rehabilitation Act. Upon request, meeting...

  19. 78 FR 45568 - Sunshine Act Meeting Notice

    2013-07-29

    ... Corporation's Institutional Advancement Committee will meet telephonically on August 6, 2013. The meeting will... transcript will be made of the closed session meeting of the Institutional Advancement Committee. The... Disabilities Act and Section 504 of the 1973 Rehabilitation Act. Upon request, meeting notices and materials...

  20. 78 FR 53480 - Sunshine Act Meeting

    2013-08-29

    ... Institutional Advancement Committee will meet telephonically on September 3, 2013. The meeting will commence at... session meeting of the Institutional Advancement Committee. The transcript of any portion of the closed... Disabilities Act and Section 504 of the 1973 Rehabilitation Act. Upon request, meeting notices and materials...

  1. 78 FR 36602 - Sunshine Act Meeting; Notice

    2013-06-18

    ... Corporation's Institutional Advancement Committee will meet telephonically on June 25, 2013. The meeting will... session meeting of the Institutional Advancement Committee. The transcript of any portion of the closed... complies with the Americans with Disabilities Act and Section 504 of the 1973 Rehabilitation Act. Upon...

  2. 78 FR 14839 - Sunshine Act Meeting

    2013-03-07

    ... Institutional Advancement Committee will meet telephonically on March 12, 2013 and March 26, 2013. Each meeting... session meeting of the Institutional Advancement Committee. The transcript of any portion of the closed... Act and Section 504 of the 1973 Rehabilitation Act. Upon request, meeting notices and materials will...

  3. 75 FR 75187 - Sunshine Act Meeting

    2010-12-02

    ... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting Notice is hereby given, pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange.... Elizabeth M. Murphy, Secretary. [FR Doc. 2010-30407 Filed 11-30-10; 4:15 pm] BILLING CODE 8011-01-P ...

  4. 10 CFR 430.61 - Prohibited acts.

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Prohibited acts. 430.61 Section 430.61 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY CONSERVATION PROGRAM FOR CONSUMER PRODUCTS Certification and... convenience of the user, the revised text is set forth as follows: § 430.61 Prohibited acts. (b) In accordance...

  5. 75 FR 12584 - Sunshine Act; Public Hearing

    2010-03-16

    ... OVERSEAS PRIVATE INVESTMENT CORPORATION Sunshine Act; Public Hearing March 17, 2010. OPIC's Sunshine Act notice of its Public Hearing in Conjunction with each Board meeting was published in the... provide testimony or submit written statements for the record; therefore, OPIC's public hearing scheduled...

  6. 75 FR 3948 - Sunshine Act Meeting

    2010-01-25

    ... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting Notice is hereby given, pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange... matters relating to climate change. At times, changes in Commission priorities require alterations in the...

  7. 78 FR 26667 - Sunshine Act Meeting

    2013-05-07

    ... first panel will examine issues in connection with the possibility of developing a credit rating... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting Notice is hereby given, pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, that the Securities and Exchange...

  8. 38 CFR 3.801 - Special acts.

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Special acts. 3.801 Section 3.801 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation Special Benefits § 3.801 Special acts. (a) General. A...

  9. 75 FR 67397 - Sunshine Act Meeting; Notice

    2010-11-02

    ... select from among those candidates for further consideration. 3. Consider and act on other business. 4... LEGAL SERVICES CORPORATION Sunshine Act Meeting; Notice Time and Date: The Legal Services Corporation Board of Directors' Search Committee for LSC President (``Search Committee'' or ``Committee...

  10. Acting green elicits a literal warm glow

    Taufik, Danny; Bolderdijk, Jan Willem; Steg, Linda

    Environmental policies are often based on the assumption that people only act environmentally friendly if some extrinsic reward is implicated, usually money(1,2). We argue that people might also be motivated by intrinsic rewards: doing the right thing (such as acting environmentally friendly)

  11. Pay Equity Act (No. 34 of 1987), 29 June 1987.

    1987-01-01

    This document contains major provisions of Ontario, Canada's 1987 Pay Equity Act. The Act seeks to redress systemic gender discrimination in compensation for work performed by employees in "female job classes" and applies to all private sector employers in Ontario with 10 or more employees, all public sector employers, and the employees of applicable employers. The Act continues to apply even if an employer subsequently reduces the number of employees below 10. The Act calls for identification of systemic gender discrimination in compensation through comparisons between female job classes and male job classes in terms of compensation and value of work performed, which is a composite of skill, effort, and responsibility normally required. Pay equity is deemed achieved when the job rate for the female job class is at least equal to the rate for a male job class in the same establishment. If there is no male job class to use for comparison, pay equity is achieved when the female job rate is at least equal to the job rate of a male job class in the same establishment that, at the time of comparison, had a higher job rate while performing work of lower value than the female job class. Differences in compensation between a female and a male job class are allowed if they result from a formal seniority system that does not discriminate on basis of gender, a temporary training or development assignment equally available to males and females, a specified merit compensation plan, actions taken as the result of a gender-neutral reevaluation process, or a skills shortage leading to a temporary inflation in compensation. Pay equity will not be achieved by reducing any employee's compensation. The Act establishes a Pay Equity Commission to oversee implementation.

  12. Review of the nuclear liability act

    1991-11-01

    The review of the Act has progressed in stages. The first stage was conducted by the staff of the Atomic Energy Control Board (AECB) and catalogued previously identified difficulties with the Act. The second stage was a preliminary examination of the Act by an Interdepartmental Working Group (IWG). The IWG was formed in 1982 at the direction of the President of the AECB. It was instructed to review all matters relating to the administration of, and experience with, the Act and to examine these matters in as much detail as was required to resolve each point raised during the review. The IWG was composed of representatives of the AECB (which administers the Act), the Department of Energy, Mines and Resources, the Department of Finance, the Department of Insurance, the Department of Justice, and the Treasury Board Secretariat

  13. Exploring primary care activities in ACT teams.

    Vanderlip, Erik R; Williams, Nancy A; Fiedorowicz, Jess G; Katon, Wayne

    2014-05-01

    People with serious mental illness often receive inadequate primary and preventive care services. Federal healthcare reform endorses team-based care that provides high quality primary and preventive care to at risk populations. Assertive community treatment (ACT) teams offer a proven, standardized treatment approach effective in improving mental health outcomes for the seriously mentally ill. Much is known about the effectiveness of ACT teams in improving mental health outcomes, but the degree to which medical care needs are addressed is not established. The purpose of this study was to explore the extent to which ACT teams address the physical health of the population they serve. ACT team leaders were invited to complete an anonymous, web-based survey to explore attitudes and activities involving the primary care needs of their clients. Information was collected regarding the use of health screening tools, physical health assessments, provision of medical care and collaboration with primary care systems. Data was analyzed from 127 team leaders across the country, of which 55 completed the entire survey. Nearly every ACT team leader believed ACT teams have a role in identifying and managing the medical co-morbidities of their clientele. ACT teams report participation in many primary care activities. ACT teams are providing a substantial amount of primary and preventive services to their population. The survey suggests standardization of physical health identification, management or referral processes within ACT teams may result in improved quality of medical care. ACT teams are in a unique position to improve physical health care by virtue of having medically trained staff and frequent, close contact with their clients.

  14. 45 CFR 2543.86 - Clean Air Act and the Federal Water Pollution Control Act.

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Clean Air Act and the Federal Water Pollution... Water Pollution Control Act. Contracts and subgrants of amounts in excess of $100,000 shall contain a... regulations issued pursuant to the Clean Air Act (42 U.S.C. 7401 et seq.) and the Federal Water Pollution...

  15. 77 FR 36231 - Americans With Disabilities Act (ADA) and Architectural Barriers Act (ABA) Accessibility...

    2012-06-18

    ...-0004] RIN 3014-AA39 Americans With Disabilities Act (ADA) and Architectural Barriers Act (ABA... (ADA) and Architectural Barriers Act (ABA) Accessibility Guidelines to specifically address emergency... ensure that newly constructed and altered emergency transportable housing units covered by the ADA or ABA...

  16. From adversary to target market: the ACT-UP boycott of Philip Morris

    Offen, N; Smith, E; Malone, R

    2003-01-01

    BACKGROUND: In 1990, the AIDS Coalition to Unleash Power (ACT-UP) sparked a year long boycott of Philip Morris's Marlboro cigarettes and Miller beer. The boycott protested the company's support of Senator Jesse Helms (R-North Carolina), a leading opponent of AIDS funding and civil rights for lesbian, gay, bisexual and transgender (LGBT) people. ACT-UP demanded that Philip Morris sever its ties with Helms and acknowledge its responsibility to the LGBT community and to people with AIDS. OBJECTI...

  17. Environment Protection (Alligator Rivers Region) Amendment Act 1987 - No 17 of 1987

    1987-01-01

    This Act amends the Environment Protection (Alligator Rivers Region) Act 1978. The amendments mainly concern definition of general mining operations and specification of the functions of the Supervisory Scientist and the Research Institute in relation to general mining in an environment conservation zone (parts of the Alligator Rivers Region). The 1978 Act provided for the appointment of a Supervising Scientist responsible for supervising protection of the environment against the effects of uranium mining in the Region, and for the creation of a Research Institute under his management. (NEA) [fr

  18. The Aggregate and Distributional Effects of the Tax Reform Act of 1986 on Firm Valuation.

    Givoly, Dan; Hayn, Carla

    1991-01-01

    The authors examine the aggregate and distributional effects of the Tax Reform Act of 1986 on equity values of publicly traded corporations. The results show that the effect of the act on the aggregate equity value of corporations was consistent with the present value of the projected added tax collection from the corporate sector. The cross-sectional variation in the magnitude and direction of the stock price response to the Tax Reform Act of 1986 was a function of both the direct and indire...

  19. The Human Rights Act: What are the implications for older people?

    2001-06-01

    Help the Aged is launching a report outlining the terms of the Human Rights Act and its implications both for older people themselves and for public bodies responsible for providing services to them. Tessa Harding, head of policy at Help the Aged said: 'The Human Rights Act is an important turning point for older people. Not only does it establish key rights of individuals to freedom from inhuman and degrading treatment, to private and family life and so on; it also prohibits discrimination in accessing these rights.We expect older people and their advocates to use the Act to ensure greater fairness and equality in our society.'

  20. Corporate Responsibility

    Waddock, Sandra; Rasche, Andreas

    2015-01-01

    We define and discuss the concept of corporate responsibility. We suggest that corporate responsibility has some unique characteristics, which makes it different from earlier conceptions of corporate social responsibility. Our discussion further shows commonalities and differences between corporate...... responsibility and related concepts, such as corporate citizenship and business ethics. We also outline some ways in which corporations have implemented corporate responsibility in practice....