Hanford Cultural Resources Laboratory annual report for fiscal year 1992

Energy Technology Data Exchange (ETDEWEB)

Chatters, J.C.; Gard, H.A.; Wright, M.K.; Crist, M.E.; Longenecker, J.G.; O`Neil, T.K.; Dawson, M.V.

1993-06-01

The Hanford Cultural Resources Laboratory (HCRL) was established by the US Department of Energy, Richland Field Office (RL) in 1987 as part of Pacific Northwest Laboratory (PNL). The HCRL provides support for managing the archaeological, historical, and cultural resources of the Hanford Site located in southcentral Washington, in a manner consistent with the National Historic Preservation Act Amended 1992 (NBPA), the Archaeological Resources Protection Act of 1979 (ARPA), the Native American Grave Protection and Repatriation Act of 1990 (NAGPRA), and the American Indian Religious Freedom Act of 1978 (AIRFA). The HCRL responsibilities have been set forth in the Hanford Cultural Resources Management Plan as a prioritized list of tasks to be undertaken to keep the RL in compliance with federal statutes, regulations, and guidelines. For FY 1992, these tasks were to (1) ensure compliance with NBPA Section 106, (2) monitor the condition of known archaeological sites, (3) evaluate cultural resources for potential nomination to the National Register of Historic Places, (4) educate the public about cultural resources, and (5) conduct a sample archaeological survey of Hanford lands. Research was also conducted as a spin-off of these tasks and is also reported here.

Catalog of Research Abstracts, 1993: Partnership opportunities at Lawrence Berkeley Laboratory

Energy Technology Data Exchange (ETDEWEB)

1993-09-01

The 1993 edition of Lawrence Berkeley Laboratory`s Catalog of Research Abstracts is a comprehensive listing of ongoing research projects in LBL`s ten research divisions. Lawrence Berkeley Laboratory (LBL) is a major multi-program national laboratory managed by the University of California for the US Department of Energy (DOE). LBL has more than 3000 employees, including over 1000 scientists and engineers. With an annual budget of approximately $250 million, LBL conducts a wide range of research activities, many that address the long-term needs of American industry and have the potential for a positive impact on US competitiveness. LBL actively seeks to share its expertise with the private sector to increase US competitiveness in world markets. LBL has transferable expertise in conservation and renewable energy, environmental remediation, materials sciences, computing sciences, and biotechnology, which includes fundamental genetic research and nuclear medicine. This catalog gives an excellent overview of LBL`s expertise, and is a good resource for those seeking partnerships with national laboratories. Such partnerships allow private enterprise access to the exceptional scientific and engineering capabilities of the federal laboratory systems. Such arrangements also leverage the research and development resources of the private partner. Most importantly, they are a means of accessing the cutting-edge technologies and innovations being discovered every day in our federal laboratories.

Sandia, California Tritium Research Laboratory transition and reutilization project

Energy Technology Data Exchange (ETDEWEB)

Garcia, T.B. [Sandia National Lab., Albuquerque, NM (United States)

1997-02-01

This paper describes a project within Sandia National Laboratory to convert the shut down Tritium Research Laboratory into a facility which could be reused within the laboratory complex. In the process of decommissioning and decontaminating the facility, the laboratory was able to save substantial financial resources by transferring much existing equipment to other DOE facilities, and then expeditiously implementing a decontamination program which has resulted in the building being converted into laboratory space for new lab programs. This project of facility reuse has been a significant financial benefit to the laboratory.

Laboratory Directed Research and Development FY 2000

International Nuclear Information System (INIS)

Hansen, Todd; Levy, Karin

2001-01-01

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Annual report on Laboratory Directed Research and Development for FY2000

Laboratory directed research and development program, FY 1996

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-02-01

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory`s forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances the Laboratory`s core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. Areas eligible for support include: (1) Work in forefront areas of science and technology that enrich Laboratory research and development capability; (2) Advanced study of new hypotheses, new experiments, and innovative approaches to develop new concepts or knowledge; (3) Experiments directed toward proof of principle for initial hypothesis testing or verification; and (4) Conception and preliminary technical analysis to explore possible instrumentation, experimental facilities, or new devices.

Hanford Cultural Resources Laboratory annual report for Fiscal Year 1991

Energy Technology Data Exchange (ETDEWEB)

Chatters, J.C.; Gard, H.A.

1992-08-01

The Hanford Cultural Resources Laboratory (HCRL) was established by the US Department of Energy, Richland Field Office (RL) in 1987 as part of Pacific Northwest Laboratory. The HCRL provides support for managing the archaeological, historical, and cultural resources of the Hanford Site, Washington, in a manner consistent with the National Historic Preservation Act of 1966 (NHPA), the Archaeological Resources Protection Act of 1979 and the American Indian Religious Freedom Act of 1978. HCRL responsibilities have been set forth in the Hanford Cultural Resources Management Plan (HCRMP) as a prioritized list of tasks to be undertaken to keep the RL in compliance with federal statutes, regulations and guidelines. For fiscal year 1991 these tasks were to (1) ensure compliance with NHPA Section 106, (2) monitor the condition of known archaeological sites, (3) evaluate cultural resources for potential nomination to the National Register of Historic Places, (4) educate the public about cultural resources, (5) conduct a sample archaeological survey of Hanford lands, and (6) gather ethnohistorical data from Indian elders. Research conducted as a spinoff from these tasks is also reported. The archaeological site monitoring program is designed to determine whether the RL`s cultural resource management and protection policies are effective; results are used in planning for cultural resource site management and protection. Forty-one sites were monitored during this fiscal year.

Hanford Cultural Resources Laboratory annual report for Fiscal Year 1991

Energy Technology Data Exchange (ETDEWEB)

Chatters, J.C.; Gard, H.A.

1992-08-01

The Hanford Cultural Resources Laboratory (HCRL) was established by the US Department of Energy, Richland Field Office (RL) in 1987 as part of Pacific Northwest Laboratory. The HCRL provides support for managing the archaeological, historical, and cultural resources of the Hanford Site, Washington, in a manner consistent with the National Historic Preservation Act of 1966 (NHPA), the Archaeological Resources Protection Act of 1979 and the American Indian Religious Freedom Act of 1978. HCRL responsibilities have been set forth in the Hanford Cultural Resources Management Plan (HCRMP) as a prioritized list of tasks to be undertaken to keep the RL in compliance with federal statutes, regulations and guidelines. For fiscal year 1991 these tasks were to (1) ensure compliance with NHPA Section 106, (2) monitor the condition of known archaeological sites, (3) evaluate cultural resources for potential nomination to the National Register of Historic Places, (4) educate the public about cultural resources, (5) conduct a sample archaeological survey of Hanford lands, and (6) gather ethnohistorical data from Indian elders. Research conducted as a spinoff from these tasks is also reported. The archaeological site monitoring program is designed to determine whether the RL's cultural resource management and protection policies are effective; results are used in planning for cultural resource site management and protection. Forty-one sites were monitored during this fiscal year.

Environmental resource document for the Idaho National Engineering Laboratory. Volume 1

Energy Technology Data Exchange (ETDEWEB)

Irving, J.S.

1993-07-01

This document contains information related to the environmental characterization of the Idaho National Engineering Laboratory (INEL). The INEL is a major US Department of Energy facility in southeastern Idaho dedicated to nuclear research, waste management, environmental restoration, and other activities related to the development of technology. Environmental information covered in this document includes land, air, water, and ecological resources; socioeconomic characteristics and land use; and cultural, aesthetic, and scenic resources.

Environmental resource document for the Idaho National Engineering Laboratory. Volume 2

Energy Technology Data Exchange (ETDEWEB)

Irving, J.S.

1993-07-01

This document contains information related to the environmental characterization of the Idaho National Engineering Laboratory (INEL). The INEL is a major US Department of Energy facility in southeastern Idaho dedicated to nuclear research, waste management, environmental restoration, and other activities related to the development of technology. Environmental information covered in this document includes land, air, water, and ecological resources; socioeconomic characteristics and land use; and cultural, aesthetic, and scenic resources.

Customizable Electronic Laboratory Online (CELO): A Web-based Data Management System Builder for Biomedical Research Laboratories

Science.gov (United States)

Fong, Christine; Brinkley, James F.

2006-01-01

A common challenge among today’s biomedical research labs is managing growing amounts of research data. In order to reduce the time and resource costs of building data management tools, we designed the Customizable Electronic Laboratory Online (CELO) system. CELO automatically creates a generic database and web interface for laboratories that submit a simple web registration form. Laboratories can then use a collection of predefined XML templates to assist with the design of a database schema. Users can immediately utilize the web-based system to query data, manage multimedia files, and securely share data remotely over the internet. PMID:17238541

Laboratory Directed Research and Development FY 2000

Energy Technology Data Exchange (ETDEWEB)

Hansen, Todd; Levy, Karin

2001-02-27

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Annual report on Laboratory Directed Research and Development for FY2000.

Laboratory directed research and development program, FY 1996

International Nuclear Information System (INIS)

1997-02-01

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory's forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances the Laboratory's core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. Areas eligible for support include: (1) Work in forefront areas of science and technology that enrich Laboratory research and development capability; (2) Advanced study of new hypotheses, new experiments, and innovative approaches to develop new concepts or knowledge; (3) Experiments directed toward proof of principle for initial hypothesis testing or verification; and (4) Conception and preliminary technical analysis to explore possible instrumentation, experimental facilities, or new devices

Laboratory challenges in the scaling up of HIV, TB, and malaria programs: The interaction of health and laboratory systems, clinical research, and service delivery.

Science.gov (United States)

Birx, Deborah; de Souza, Mark; Nkengasong, John N

2009-06-01

Strengthening national health laboratory systems in resource-poor countries is critical to meeting the United Nations Millennium Development Goals. Despite strong commitment from the international community to fight major infectious diseases, weak laboratory infrastructure remains a huge rate-limiting step. Some major challenges facing laboratory systems in resource-poor settings include dilapidated infrastructure; lack of human capacity, laboratory policies, and strategic plans; and limited synergies between clinical and research laboratories. Together, these factors compromise the quality of test results and impact patient management. With increased funding, the target of laboratory strengthening efforts in resource-poor countries should be the integrating of laboratory services across major diseases to leverage resources with respect to physical infrastructure; types of assays; supply chain management of reagents and equipment; and maintenance of equipment.

Government-industry-uUniversity and rResearch lLaboratories cCoordination for new product development: Session 2. Government research laboratory perspective

International Nuclear Information System (INIS)

Kuzay, T.M.

1997-01-01

This talk is the second in an expanded series of presentations on the Government-Industry-University and Research Laboratories Coordination for new product development, which is a timely and important public policy issue. Such interactions have become particularly timely in light of the present decline in funding for research and development (R ampersand D) in the nation''s budget and in the private sector. These interactions, at least in principle, provide a means to maximize benefits for the greater good of the nation by pooling the diminishing resources. National laboratories, which traditionally interacted closely with the universities in educational training, now are able to also participate closely with industry in joint R ampersand D thanks to a number of public laws legislated since the early 80s. A review of the experiences with such interactions at Argonne National Laboratory, which exemplifies the national laboratories, shows that, despite differences in their traditions and the missions, the national laboratory-industry-university triangle can work together

Laboratory-Directed Research and Development 2016 Summary Annual Report

International Nuclear Information System (INIS)

Pillai, Rekha Sukamar; Jacobson, Julie Ann

2017-01-01

energy deployment, and secure and modernize critical infrastructure. INL's research, development, and demonstration capabilities, its resources, and its unique geography enable integration of scientific discovery, innovation, engineering, operations, and controls into complex large-scale testbeds for discovery, innovation, and demonstration of transformational clean energy and security concepts. These attributes strengthen INL's leadership as a demonstration laboratory. As a national resource, INL also applies its capabilities and skills to the specific needs of other federal agencies and customers through DOE's Strategic Partnership Program.

NATURAL RESOURCE MANAGEMENT PLAN FOR BROOKHAVEN NATIONAL LABORATORY.

Energy Technology Data Exchange (ETDEWEB)

GREEN,T.ET AL.

2003-12-31

Brookhaven National Laboratory (BNL) is located near the geographic center of Long Island, New York. The Laboratory is situated on 5,265 acres of land composed of Pine Barrens habitat with a central area developed for Laboratory work. In the mid-1990s BNL began developing a wildlife management program. This program was guided by the Wildlife Management Plan (WMP), which was reviewed and approved by various state and federal agencies in September 1999. The WMP primarily addressed concerns with the protection of New York State threatened, endangered, or species of concern, as well as deer populations, invasive species management, and the revegetation of the area surrounding the Relativistic Heavy Ion Collider (RHIC). The WMP provided a strong and sound basis for wildlife management and established a basis for forward motion and the development of this document, the Natural Resource Management Plan (NRMP), which will guide the natural resource management program for BNL. The body of this plan establishes the management goals and actions necessary for managing the natural resources at BNL. The appendices provide specific management requirements for threatened and endangered amphibians and fish (Appendices A and B respectively), lists of actions in tabular format (Appendix C), and regulatory drivers for the Natural Resource Program (Appendix D). The purpose of the Natural Resource Management Plan is to provide management guidance, promote stewardship of the natural resources found at BNL, and to integrate their protection with pursuit of the Laboratory's mission. The philosophy or guiding principles of the NRMP are stewardship, adaptive ecosystem management, compliance, integration with other plans and requirements, and incorporation of community involvement, where applicable.

Laboratory directed research and development program FY 1999

Energy Technology Data Exchange (ETDEWEB)

Hansen, Todd; Levy, Karin

2000-03-08

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. This is the annual report on Laboratory Directed Research and Development (LDRD) program for FY99.

Laboratory Directed Research and Development Program FY 2001

Energy Technology Data Exchange (ETDEWEB)

Hansen, Todd; Levy, Karin

2002-03-15

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. This is the annual report on Laboratory Directed Research and Development (LDRD) program for FY01.

Annual Report (fiscal 1995, No. 10) of Research Laboratory of Carbonaceous Resources Conversion Technology, Kyoto University; Kyoto Daigaku Kogakubu jushitsu tanso shigen tenkan kogaku jikken shisetsu nenpo (19995 nendo No. 10)

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-07-01

The report covers Laboratory research activities and a decision that the Laboratory, established in April 1986, will be abolished as scheduled in April 1996. Important coal-related achievements of the Laboratory include the development of a rapid pyrolytic process, studies on coal gasification, propositions for enabling coal to dissolve into general-purpose solvents and for a liquid phase oxidation process, manufacture of advanced-function carbon materials from heavy-weight carbonaceous resources (development of next-generation coke production techniques and of various element techniques for the clean use of coal), etc. As for its activities both domestic and international, the Laboratory, engaged in Education Ministry-financed high-priority scientific research projects, represented the general affairs division in a study titled 'Utilization of various energy resources,' and represented groups participating in other projects titled 'Development of new coal-gasification process' and 'Development of integral conversion process aiming at comprehensive coal utilization.' Furthermore, the Laboratory led the 'Japan-Canada cooperative scientific research relating to the development of technologies for effective coal utilization.' (NEDO)

Annual Report (fiscal 1995, No. 10) of Research Laboratory of Carbonaceous Resources Conversion Technology, Kyoto University; Kyoto Daigaku Kogakubu jushitsu tanso shigen tenkan kogaku jikken shisetsu nenpo (19995 nendo No. 10)

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-07-01

The report covers Laboratory research activities and a decision that the Laboratory, established in April 1986, will be abolished as scheduled in April 1996. Important coal-related achievements of the Laboratory include the development of a rapid pyrolytic process, studies on coal gasification, propositions for enabling coal to dissolve into general-purpose solvents and for a liquid phase oxidation process, manufacture of advanced-function carbon materials from heavy-weight carbonaceous resources (development of next-generation coke production techniques and of various element techniques for the clean use of coal), etc. As for its activities both domestic and international, the Laboratory, engaged in Education Ministry-financed high-priority scientific research projects, represented the general affairs division in a study titled 'Utilization of various energy resources,' and represented groups participating in other projects titled 'Development of new coal-gasification process' and 'Development of integral conversion process aiming at comprehensive coal utilization.' Furthermore, the Laboratory led the 'Japan-Canada cooperative scientific research relating to the development of technologies for effective coal utilization.' (NEDO)

Simula Research Laboratory

CERN Document Server

Tveito, Aslak

2010-01-01

The Simula Research Laboratory, located just outside Oslo in Norway, is rightly famed as a highly successful research facility, despite being, at only eight years old, a very young institution. This fascinating book tells the history of Simula, detailing the culture and values that have been the guiding principles of the laboratory throughout its existence. Dedicated to tackling scientific challenges of genuine social importance, the laboratory undertakes important research with long-term implications in networks, computing and software engineering, including specialist work in biomedical comp

Laboratory-Directed Research and Development 2016 Summary Annual Report

Energy Technology Data Exchange (ETDEWEB)

Pillai, Rekha Sukamar [Idaho National Lab. (INL), Idaho Falls, ID (United States); Jacobson, Julie Ann [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2017-01-01

, enable clean energy deployment, and secure and modernize critical infrastructure. INL’s research, development, and demonstration capabilities, its resources, and its unique geography enable integration of scientific discovery, innovation, engineering, operations, and controls into complex large-scale testbeds for discovery, innovation, and demonstration of transformational clean energy and security concepts. These attributes strengthen INL’s leadership as a demonstration laboratory. As a national resource, INL also applies its capabilities and skills to the specific needs of other federal agencies and customers through DOE’s Strategic Partnership Program.

Argonne Laboratory Computing Resource Center - FY2004 Report.

Energy Technology Data Exchange (ETDEWEB)

Bair, R.

2005-04-14

In the spring of 2002, Argonne National Laboratory founded the Laboratory Computing Resource Center, and in April 2003 LCRC began full operations with Argonne's first teraflops computing cluster. The LCRC's driving mission is to enable and promote computational science and engineering across the Laboratory, primarily by operating computing facilities and supporting application use and development. This report describes the scientific activities, computing facilities, and usage in the first eighteen months of LCRC operation. In this short time LCRC has had broad impact on programs across the Laboratory. The LCRC computing facility, Jazz, is available to the entire Laboratory community. In addition, the LCRC staff provides training in high-performance computing and guidance on application usage, code porting, and algorithm development. All Argonne personnel and collaborators are encouraged to take advantage of this computing resource and to provide input into the vision and plans for computing and computational analysis at Argonne. Steering for LCRC comes from the Computational Science Advisory Committee, composed of computing experts from many Laboratory divisions. The CSAC Allocations Committee makes decisions on individual project allocations for Jazz.

National Renewable Energy Laboratory 2003 Research Review

Energy Technology Data Exchange (ETDEWEB)

2004-04-01

In-depth articles on several NREL technologies and advances, including: production of hydrogen using renewable resources and technologies; use of carbon nanotubes for storing hydrogen; enzymatic reduction of cellulose to simple sugars as a platform for making fuel, chemicals, and materials; and the potential of electricity from wind energy to offset carbon dioxide emissions. Also covered are NREL news, awards and honors received by the Laboratory, and patents granted to NREL researchers.

Natural Resource Management Plan for Brookhaven National Laboratory

Energy Technology Data Exchange (ETDEWEB)

green, T.

2011-08-15

This comprehensive Natural Resource Management Plan (NRMP) for Brookhaven National Laboratory (BNL) was built on the successful foundation of the Wildlife Management Plan for BNL, which it replaces. This update to the 2003 plan continues to build on successes and efforts to better understand the ecosystems and natural resources found on the BNL site. The plan establishes the basis for managing the varied natural resources located on the 5,265 acre BNL site, setting goals and actions to achieve those goals. The planning of this document is based on the knowledge and expertise gained over the past 10 years by the Natural Resources management staff at BNL in concert with local natural resource agencies including the New York State Department of Environmental Conservation, Long Island Pine Barrens Joint Planning and Policy Commission, The Nature Conservancy, and others. The development of this plan is an attempt at sound ecological management that not only benefits BNL's ecosystems but also benefits the greater Pine Barrens habitats in which BNL is situated. This plan applies equally to the Upton Ecological and Research Reserve (Upton Reserve). Any difference in management between the larger BNL area and the Upton Reserve are noted in the text. The purpose of the Natural Resource Management Plan (NRMP) is to provide management guidance, promote stewardship of the natural resources found at BNL, and to sustainably integrate their protection with pursuit of the Laboratory's mission. The philosophy or guiding principles of the NRMP are stewardship, sustainability, adaptive ecosystem management, compliance, integration with other plans and requirements, and the incorporation of community involvement, where applicable. The NRMP is periodically reviewed and updated, typically every five years. This review and update was delayed to develop documents associated with a new third party facility, the Long Island Solar Farm. This two hundred acre facility will result in

Laboratory Directed Research and Development Program FY98

Energy Technology Data Exchange (ETDEWEB)

Hansen, T. [ed.; Chartock, M.

1999-02-05

The Ernest Orlando Lawrence Berkeley National Laboratory (LBNL or Berkeley Lab) Laboratory Directed Research and Development Program FY 1998 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the supported projects and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The LBNL LDRD program is a critical tool for directing the Laboratory's forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for LBNL scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances LBNL's core competencies, foundations, and scientific capability, and permits exploration of exciting new opportunities. All projects are work in forefront areas of science and technology. Areas eligible for support include the following: Advanced study of hypotheses, concepts, or innovative approaches to scientific or technical problems; Experiments and analyses directed toward ''proof of principle'' or early determination of the utility of new scientific ideas, technical concepts, or devices; and Conception and preliminary technical analyses of experimental facilities or devices.

Open- and closed-formula laboratory animal diets and their importance to research.

Science.gov (United States)

Barnard, Dennis E; Lewis, Sherry M; Teter, Beverly B; Thigpen, Julius E

2009-11-01

Almost 40 y ago the scientific community was taking actions to control environmental factors that contribute to variation in the responses of laboratory animals to scientific manipulation. Laboratory animal diet was recognized as an important variable. During the 1970s, the American Institute of Nutrition, National Academy of Science, Institute of Laboratory Animal Resources, and Laboratory Animals Centre Diets Advisory Committee supported the use of 'standard reference diets' in biomedical research as a means to improve the ability to replicate research. As a result the AIN76 purified diet was formulated. During this same time, the laboratory animal nutritionist at the NIH was formulating open-formula, natural-ingredient diets to meet the need for standardized laboratory animal diets. Since the development of open-formula diets, fixed-formula and constant-nutrient-concentration closed-formula laboratory animal natural ingredient diets have been introduced to help reduce the potential variation diet can cause in research.

The NIH-NIAID Filariasis Research Reagent Resource Center.

Directory of Open Access Journals (Sweden)

Michelle L Michalski

2011-11-01

Full Text Available Filarial worms cause a variety of tropical diseases in humans; however, they are difficult to study because they have complex life cycles that require arthropod intermediate hosts and mammalian definitive hosts. Research efforts in industrialized countries are further complicated by the fact that some filarial nematodes that cause disease in humans are restricted in host specificity to humans alone. This potentially makes the commitment to research difficult, expensive, and restrictive. Over 40 years ago, the United States National Institutes of Health-National Institute of Allergy and Infectious Diseases (NIH-NIAID established a resource from which investigators could obtain various filarial parasite species and life cycle stages without having to expend the effort and funds necessary to maintain the entire life cycles in their own laboratories. This centralized resource (The Filariasis Research Reagent Resource Center, or FR3 translated into cost savings to both NIH-NIAID and to principal investigators by freeing up personnel costs on grants and allowing investigators to divert more funds to targeted research goals. Many investigators, especially those new to the field of tropical medicine, are unaware of the scope of materials and support provided by the FR3. This review is intended to provide a short history of the contract, brief descriptions of the fiilarial species and molecular resources provided, and an estimate of the impact the resource has had on the research community, and describes some new additions and potential benefits the resource center might have for the ever-changing research interests of investigators.

New working paradigms in research laboratories.

Science.gov (United States)

Keighley, Wilma; Sewing, Andreas

2009-07-01

Work in research laboratories, especially within centralised functions in larger organisations, is changing fast. With easier access to external providers and Contract Research Organisations, and a focus on budgets and benchmarking, scientific expertise has to be complemented with operational excellence. New concepts, globally shared projects and restricted resources highlight the constraints of traditional operating models working from Monday to Friday and nine to five. Whilst many of our scientists welcome this new challenge, organisations have to enable and foster a more business-like mindset. Organisational structures, remuneration, as well as systems in finance need to be adapted to build operations that are best-in-class rather than merely minimising negative impacts of current organisational structures.

Combustion Research Laboratory

Data.gov (United States)

Federal Laboratory Consortium — The Combustion Research Laboratory facilitates the development of new combustion systems or improves the operation of existing systems to meet the Army's mission for...

Evaluating Solar Resource Data Obtained from Multiple Radiometers Deployed at the National Renewable Energy Laboratory: Preprint

Energy Technology Data Exchange (ETDEWEB)

Habte, A.; Sengupta, M.; Andreas, A.; Wilcox, S.; Stoffel, T.

2014-09-01

Solar radiation resource measurements from radiometers are used to predict and evaluate the performance of photovoltaic and concentrating solar power systems, validate satellite-based models for estimating solar resources, and advance research in solar forecasting and climate change. This study analyzes the performance of various commercially available radiometers used for measuring global horizontal irradiances (GHI) and direct normal irradiances (DNI). These include pyranometers, pyrheliometers, rotating shadowband irradiometers, and a pyranometer with a shading ring deployed at the National Renewable Energy Laboratory's Solar Radiation Research Laboratory (SRRL). The radiometers in this study were deployed for one year (from April 1, 2011, through March 31, 2012) and compared to measurements from radiometers with the lowest values of estimated measurement uncertainties for producing reference GHI and DNI.

Laboratory Directed Research and Development Program FY 2006

Energy Technology Data Exchange (ETDEWEB)

Hansen (Ed.), Todd

2007-03-08

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness.

Laboratory Directed Research and Development Program FY 2005 Annual Report

Energy Technology Data Exchange (ETDEWEB)

Sjoreen, Terrence P [ORNL

2006-04-01

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2A, 'Laboratory Directed Research and Development' (January 8, 2001), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report describes all ORNL LDRD research activities supported during FY 2005 and includes final reports for completed projects and shorter progress reports for projects that were active, but not completed, during this period. The FY 2005 ORNL LDRD Self-Assessment (ORNL/PPA-2006/2) provides financial data about the FY 2005 projects and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching national security mission, which encompasses science, energy resources, environmental quality, and national nuclear security. As a national resource, the Laboratory also applies its capabilities and skills to the specific needs of other federal agencies and customers through the DOE Work For Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at . LDRD is a relatively small but vital DOE program that allows ORNL, as well as other multiprogram DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the

Laboratory Directed Research and Development Program FY 2004 Annual Report

Energy Technology Data Exchange (ETDEWEB)

Sjoreen, Terrence P [ORNL

2005-04-01

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2A, 'Laboratory Directed Research and Development' (January 8, 2001), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report describes all ORNL LDRD research activities supported during FY 2004 and includes final reports for completed projects and shorter progress reports for projects that were active, but not completed, during this period. The FY 2004 ORNL LDRD Self-Assessment (ORNL/PPA-2005/2) provides financial data about the FY 2004 projects and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching national security mission, which encompasses science, energy resources, environmental quality, and national nuclear security. As a national resource, the Laboratory also applies its capabilities and skills to the specific needs of other federal agencies and customers through the DOE Work For Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at . LDRD is a relatively small but vital DOE program that allows ORNL, as well as other multiprogram DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the

Argonne's Laboratory computing resource center : 2006 annual report.

Energy Technology Data Exchange (ETDEWEB)

Bair, R. B.; Kaushik, D. K.; Riley, K. R.; Valdes, J. V.; Drugan, C. D.; Pieper, G. P.

2007-05-31

Argonne National Laboratory founded the Laboratory Computing Resource Center (LCRC) in the spring of 2002 to help meet pressing program needs for computational modeling, simulation, and analysis. The guiding mission is to provide critical computing resources that accelerate the development of high-performance computing expertise, applications, and computations to meet the Laboratory's challenging science and engineering missions. In September 2002 the LCRC deployed a 350-node computing cluster from Linux NetworX to address Laboratory needs for mid-range supercomputing. This cluster, named 'Jazz', achieved over a teraflop of computing power (10{sup 12} floating-point calculations per second) on standard tests, making it the Laboratory's first terascale computing system and one of the 50 fastest computers in the world at the time. Jazz was made available to early users in November 2002 while the system was undergoing development and configuration. In April 2003, Jazz was officially made available for production operation. Since then, the Jazz user community has grown steadily. By the end of fiscal year 2006, there were 76 active projects on Jazz involving over 380 scientists and engineers. These projects represent a wide cross-section of Laboratory expertise, including work in biosciences, chemistry, climate, computer science, engineering applications, environmental science, geoscience, information science, materials science, mathematics, nanoscience, nuclear engineering, and physics. Most important, many projects have achieved results that would have been unobtainable without such a computing resource. The LCRC continues to foster growth in the computational science and engineering capability and quality at the Laboratory. Specific goals include expansion of the use of Jazz to new disciplines and Laboratory initiatives, teaming with Laboratory infrastructure providers to offer more scientific data management capabilities, expanding Argonne staff

Concierge: Personal database software for managing digital research resources

Directory of Open Access Journals (Sweden)

Hiroyuki Sakai

2007-11-01

Full Text Available This article introduces a desktop application, named Concierge, for managing personal digital research resources. Using simple operations, it enables storage of various types of files and indexes them based on content descriptions. A key feature of the software is a high level of extensibility. By installing optional plug-ins, users can customize and extend the usability of the software based on their needs. In this paper, we also introduce a few optional plug-ins: literaturemanagement, electronic laboratory notebook, and XooNlps client plug-ins. XooNIps is a content management system developed to share digital research resources among neuroscience communities. It has been adopted as the standard database system in Japanese neuroinformatics projects. Concierge, therefore, offers comprehensive support from management of personal digital research resources to their sharing in open-access neuroinformatics databases such as XooNIps. This interaction between personal and open-access neuroinformatics databases is expected to enhance the dissemination of digital research resources. Concierge is developed as an open source project; Mac OS X and Windows XP versions have been released at the official site (http://concierge.sourceforge.jp.

Effect of virtual analytical chemistry laboratory on enhancing student research skills and practices

Directory of Open Access Journals (Sweden)

Boris Bortnik

2017-12-01

Full Text Available This article aims to determine the effect of a virtual chemistry laboratory on university student achievement. The article describes a model of a laboratory course that includes a virtual component. This virtual component is viewed as a tool of student pre-lab autonomous learning. It presents electronic resources designed for a virtual laboratory and outlines the methodology of e-resource application. To find out how virtual chemistry laboratory affects student scientific literacy, research skills and practices, a pedagogical experiment has been conducted. Student achievement was compared in two learning environments: traditional – in-class hands-on – learning (control group and blended learning – online learning combined with in-person learning (experimental group. The effectiveness of integrating an e-lab in the laboratory study was measured by comparing student lab reports of the two groups. For that purpose, a set of 10 criteria was developed. The experimental and control student groups were also compared in terms of test results and student portfolios. The study showed that the adopted approach blending both virtual and hands-on learning environments has the potential to enhance student research skills and practices in analytical chemistry studies.

Argonne's Laboratory Computing Resource Center : 2005 annual report.

Energy Technology Data Exchange (ETDEWEB)

Bair, R. B.; Coghlan, S. C; Kaushik, D. K.; Riley, K. R.; Valdes, J. V.; Pieper, G. P.

2007-06-30

Argonne National Laboratory founded the Laboratory Computing Resource Center in the spring of 2002 to help meet pressing program needs for computational modeling, simulation, and analysis. The guiding mission is to provide critical computing resources that accelerate the development of high-performance computing expertise, applications, and computations to meet the Laboratory's challenging science and engineering missions. The first goal of the LCRC was to deploy a mid-range supercomputing facility to support the unmet computational needs of the Laboratory. To this end, in September 2002, the Laboratory purchased a 350-node computing cluster from Linux NetworX. This cluster, named 'Jazz', achieved over a teraflop of computing power (10{sup 12} floating-point calculations per second) on standard tests, making it the Laboratory's first terascale computing system and one of the fifty fastest computers in the world at the time. Jazz was made available to early users in November 2002 while the system was undergoing development and configuration. In April 2003, Jazz was officially made available for production operation. Since then, the Jazz user community has grown steadily. By the end of fiscal year 2005, there were 62 active projects on Jazz involving over 320 scientists and engineers. These projects represent a wide cross-section of Laboratory expertise, including work in biosciences, chemistry, climate, computer science, engineering applications, environmental science, geoscience, information science, materials science, mathematics, nanoscience, nuclear engineering, and physics. Most important, many projects have achieved results that would have been unobtainable without such a computing resource. The LCRC continues to improve the computational science and engineering capability and quality at the Laboratory. Specific goals include expansion of the use of Jazz to new disciplines and Laboratory initiatives, teaming with Laboratory infrastructure

Energy Materials Research Laboratory (EMRL)

Data.gov (United States)

Federal Laboratory Consortium — The Energy Materials Research Laboratory at the Savannah River National Laboratory (SRNL) creates a cross-disciplinary laboratory facility that lends itself to the...

Small-Engine Research Laboratory (SERL)

Data.gov (United States)

Federal Laboratory Consortium — Description: The Small-Engine Research Laboratory (SERL) is a facility designed to conduct experimental small-scale propulsion and power generation systems research....

Land and water resources for environmental research on Oak Ridge Reservation

International Nuclear Information System (INIS)

Dahlman, R.C.; Kitchings, J.T.; Elwood, J.W.

1977-01-01

Resources for environmental research on the Oak Ridge Reservation are analogous to the highly complex, physical and engineering facilities of the Oak Ridge National Laboratory. Consequently, land and water resources have been committed to comprehensive research for the purpose of providing relevant, scientific insights on environmental problems associated with ERDA's programs. Diverse aquatic, terrestrial, and agricultural ecosystems are designated for short- and long-term research related to environmental impacts or benefits of different energy technologies. Examples of ecosystems employed in this research include hardwood and pine forests, grasslands and pastures, free-flowing streams and impounded reservoirs, field plots, contaminated environmental natural areas, an array of animal habitats, and calibrated watersheds. Some of the characteristic biota of habitat ecosystems are described in the document. Documentation and planning for use of these lands, waters, and biotic resources also respond to the broad issue of appropriate usage of Federal lands

Land and water resources for environmental research on Oak Ridge Reservation

Energy Technology Data Exchange (ETDEWEB)

Dahlman, R.C.; Kitchings, J.T.; Elwood, J.W.

1977-01-01

Resources for environmental research on the Oak Ridge Reservation are analogous to the highly complex, physical and engineering facilities of the Oak Ridge National Laboratory. Consequently, land and water resources have been committed to comprehensive research for the purpose of providing relevant, scientific insights on environmental problems associated with ERDA's programs. Diverse aquatic, terrestrial, and agricultural ecosystems are designated for short- and long-term research related to environmental impacts or benefits of different energy technologies. Examples of ecosystems employed in this research include hardwood and pine forests, grasslands and pastures, free-flowing streams and impounded reservoirs, field plots, contaminated environmental natural areas, an array of animal habitats, and calibrated watersheds. Some of the characteristic biota of habitat ecosystems are described in the document. Documentation and planning for use of these lands, waters, and biotic resources also respond to the broad issue of appropriate usage of Federal lands.

Research Combustion Laboratory (RCL)

Data.gov (United States)

Federal Laboratory Consortium — The Research Combustion Laboratory (RCL) develops aerospace propulsion technology by performing tests on propulsion components and materials. Altitudes up to 137,000...

Zoonoses of occupational health importance in contemporary laboratory animal research.

Science.gov (United States)

Hankenson, F Claire; Johnston, Nancy A; Weigler, Benjamin J; Di Giacomo, Ronald F

2003-12-01

In contemporary laboratory animal facilities, workplace exposure to zoonotic pathogens, agents transmitted to humans from vertebrate animals or their tissues, is an occupational hazard. The primary (e.g., macaques, pigs, dogs, rabbits, mice, and rats) and secondary species (e.g., sheep, goats, cats, ferrets, and pigeons) of animals commonly used in biomedical research, as classified by the American College of Laboratory Animal Medicine, are established or potential hosts for a large number of zoonotic agents. Diseases included in this review are principally those wherein a risk to biomedical facility personnel has been documented by published reports of human cases in laboratory animal research settings, or under reasonably similar circumstances. Diseases are listed alphabetically, and each section includes information about clinical disease, transmission, occurrence, and prevention in animal reservoir species and humans. Our goal is to provide a resource for veterinarians, health-care professionals, technical staff, and administrators that will assist in the design and on-going evaluation of institutional occupational health and safety programs.

Institutional shared resources and translational cancer research

Directory of Open Access Journals (Sweden)

De Paoli Paolo

2009-06-01

Full Text Available Abstract The development and maintenance of adequate shared infrastructures is considered a major goal for academic centers promoting translational research programs. Among infrastructures favoring translational research, centralized facilities characterized by shared, multidisciplinary use of expensive laboratory instrumentation, or by complex computer hardware and software and/or by high professional skills are necessary to maintain or improve institutional scientific competitiveness. The success or failure of a shared resource program also depends on the choice of appropriate institutional policies and requires an effective institutional governance regarding decisions on staffing, existence and composition of advisory committees, policies and of defined mechanisms of reporting, budgeting and financial support of each resource. Shared Resources represent a widely diffused model to sustain cancer research; in fact, web sites from an impressive number of research Institutes and Universities in the U.S. contain pages dedicated to the SR that have been established in each Center, making a complete view of the situation impossible. However, a nation-wide overview of how Cancer Centers develop SR programs is available on the web site for NCI-designated Cancer Centers in the U.S., while in Europe, information is available for individual Cancer centers. This article will briefly summarize the institutional policies, the organizational needs, the characteristics, scientific aims, and future developments of SRs necessary to develop effective translational research programs in oncology. In fact, the physical build-up of SRs per se is not sufficient for the successful translation of biomedical research. Appropriate policies to improve the academic culture in collaboration, the availability of educational programs for translational investigators, the existence of administrative facilitations for translational research and an efficient organization

Institutional shared resources and translational cancer research.

Science.gov (United States)

De Paoli, Paolo

2009-06-29

The development and maintenance of adequate shared infrastructures is considered a major goal for academic centers promoting translational research programs. Among infrastructures favoring translational research, centralized facilities characterized by shared, multidisciplinary use of expensive laboratory instrumentation, or by complex computer hardware and software and/or by high professional skills are necessary to maintain or improve institutional scientific competitiveness. The success or failure of a shared resource program also depends on the choice of appropriate institutional policies and requires an effective institutional governance regarding decisions on staffing, existence and composition of advisory committees, policies and of defined mechanisms of reporting, budgeting and financial support of each resource. Shared Resources represent a widely diffused model to sustain cancer research; in fact, web sites from an impressive number of research Institutes and Universities in the U.S. contain pages dedicated to the SR that have been established in each Center, making a complete view of the situation impossible. However, a nation-wide overview of how Cancer Centers develop SR programs is available on the web site for NCI-designated Cancer Centers in the U.S., while in Europe, information is available for individual Cancer centers. This article will briefly summarize the institutional policies, the organizational needs, the characteristics, scientific aims, and future developments of SRs necessary to develop effective translational research programs in oncology.In fact, the physical build-up of SRs per se is not sufficient for the successful translation of biomedical research. Appropriate policies to improve the academic culture in collaboration, the availability of educational programs for translational investigators, the existence of administrative facilitations for translational research and an efficient organization supporting clinical trial recruitment

Annual Report (No. 9, fiscal 1994) of Research Laboratory of Carbonaceous Resources Conversion Technology, Kyoto University; Kyoto Daigaku Kogakubu jushitsu tanso shigen tenkan kogaku jikken shisetsu nenpo (1994 nendo No.9)

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-06-01

Research activities at the above institute are reported. In an effort to develop advanced coal utilization techniques aiming at reduction in environmental impact, coals of Canadian origin are investigated in cooperation with Canadian researchers. Outstanding among the achievements are Professor Morio Okazaki's 'Study of manipulation of transfer of heat and substance in porous solid bodies' (winner of prize from The Society of Chemical Engineers, Japan), and Professor Tomoyuki Inui's 'Study of fuel synthesis using porous crystalline catalysts' (winner of prize from The Japan Institute of Energy). Various studies are now under way, which include the development of a technique of high-efficiency pyrolysis for coal etc. at the Research Laboratory of Carbonaceous Resources Conversion Technology; development of a zeolite separation membrane on a ceramic filter at the Hashimoto Laboratory specializing in chemical engineering; measurement of the effect of hydrostatic pressure in active carbon adsorption, research on the state of liquid phase adsorption, etc., at the Okazaki Laboratory; analysis of heated fluid in porous structures by means of the lattice Boltzmann method etc. at the Ogino Laboratory; research on coal liquefaction using iron/sulfur-based catalysts etc. at the Watanabe Laboratory. (NEDO)

Annual Report (No. 9, fiscal 1994) of Research Laboratory of Carbonaceous Resources Conversion Technology, Kyoto University; Kyoto Daigaku Kogakubu jushitsu tanso shigen tenkan kogaku jikken shisetsu nenpo (1994 nendo No.9)

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-06-01

Research activities at the above institute are reported. In an effort to develop advanced coal utilization techniques aiming at reduction in environmental impact, coals of Canadian origin are investigated in cooperation with Canadian researchers. Outstanding among the achievements are Professor Morio Okazaki's 'Study of manipulation of transfer of heat and substance in porous solid bodies' (winner of prize from The Society of Chemical Engineers, Japan), and Professor Tomoyuki Inui's 'Study of fuel synthesis using porous crystalline catalysts' (winner of prize from The Japan Institute of Energy). Various studies are now under way, which include the development of a technique of high-efficiency pyrolysis for coal etc. at the Research Laboratory of Carbonaceous Resources Conversion Technology; development of a zeolite separation membrane on a ceramic filter at the Hashimoto Laboratory specializing in chemical engineering; measurement of the effect of hydrostatic pressure in active carbon adsorption, research on the state of liquid phase adsorption, etc., at the Okazaki Laboratory; analysis of heated fluid in porous structures by means of the lattice Boltzmann method etc. at the Ogino Laboratory; research on coal liquefaction using iron/sulfur-based catalysts etc. at the Watanabe Laboratory. (NEDO)

Institutional training programs for research personnel conducted by laboratory-animal veterinarians.

Science.gov (United States)

Dyson, Melissa C; Rush, Howard G

2012-01-01

Research institutions are required by federal law and national standards to ensure that individuals involved in animal research are appropriately trained in techniques and procedures used on animals. Meeting these requirements necessitates the support of institutional authorities; policies for the documentation and enforcement of training; resources to support and provide training programs; and high-quality, effective educational material. Because of their expertise, laboratory-animal veterinarians play an essential role in the design, implementation, and provision of educational programs for faculty, staff, and students in biomedical research. At large research institutions, provision of a training program for animal care and use personnel can be challenging because of the animal-research enterprise's size and scope. At the University of Michigan (UM), approximately 3,500 individuals have direct contact with animals used in research. We describe a comprehensive educational program for animal care and use personnel designed and provided by laboratory-animal veterinarians at UM and discuss the challenges associated with its implementation.

Sunspots Resource--From Ancient Cultures to Modern Research

Science.gov (United States)

Craig, N.

2000-10-01

Sunspots is a web-based lesson that was developed by the Science Education Gateway (SEGway) program with participants from the Exploratorium, a well known science Museum in San Francisco, UC Berkeley Space Sciences Laboratory, and teachers from several California schools. This space science resource allows 8-12 grade students to explore the nature of sunspots and the history of solar physics in its effort to understand their nature. Interviews with solar physicists and archeo-astronomers, historic images, cutting-edge NASA images, movies, and research results, as well as a student-centered sunspot research activity using NASA space science data defines this lesson. The sunspot resource is aligned with the NCTM and National Science Education Standards. It emphasizes inquiry-based methods and mathematical exercises through measurement, graphic data representation, analysis of NASA data, lastly, interpreting results and drawing conclusions. These resources have been successfully classroom tested in 4 middle schools in the San Francisco Unified School District as part of the 3-week Summer School Science curricula. Lessons learned from the Summer School 1999 will be explained. This resource includes teacher-friendly lesson plans, space science background material and student worksheets. There will be Sunspots lesson CD-ROM and printed version of the relevant classroom-ready materials and a teacher resource booklet available. Sunspot resource is brought to you by, The Science Education Gateway - SEGway - Project, and the HESSI satellite and NASA's Office of Space Science Sun-Earth Connection Education Forum.

Pacific Northwest Laboratory annual report for 1993 to the DOE Office of Energy Research

International Nuclear Information System (INIS)

1994-04-01

This 1993 Annual Report from Pacific Northwest Laboratory (PNL) to the US DOE describes research in environment and health conducted during fiscal year (FY) 1993. The report is divided into four parts, each in a separate volume. This part, Volume 2, covers Environmental Sciences. The research is directed toward developing a fundamental understanding of subsurface and terrestrial systems as a basis for both managing these critical resources and addressing environmental problems such as environmental restoration and global change. There are sections on Subsurface Science, Terrestrial Science, Technology Transfer, Interactions with Educational Institutions, and Laboratory Directed Research and Development

JV Task 6 - Coal Ash Resources Research Consortium Research

Energy Technology Data Exchange (ETDEWEB)

Debra Pflughoeft-Hassett; Tera Buckley; Bruce Dockter; Kurt Eylands; David Hassett; Loreal Heebink; Erick Zacher

2008-04-01

The Coal Ash Resources Research Consortium{reg_sign} (CARRC{reg_sign}, pronounced 'cars') focuses on performing fundamental and applied scientific and engineering research emphasizing the environmentally safe, economical use of coal combustion by-products (CCBs). CARRC member organizations, which include utilities and marketers, are key to developing industry-driven research in the area of CCB utilization and ensuring its successful application. The U.S. Department of Energy is a partner in CARRC through the EERC Jointly Sponsored Research Program (JSRP), which provides matching funds for industrial member contributions and facilitates an increased level of effort in CARRC. CARRC tasks were designed to provide information on CCB performance, including environmental performance, engineering performance, favorable economics, and improved life cycle of products and projects. CARRC technical research tasks are developed based on member input and prioritization. CARRC special projects are developed with members and nonmembers to provide similar information and to support activities, including the assembly and interpretation of data, support for standards development and technology transfer, and facilitating product development and testing. CARRC activities from 1998 to 2007 included a range of research tasks, with primary work performed in laboratory tasks developed to answer specific questions or evaluate important fundamental properties of CCBs. CARRC topical reports were prepared on several completed tasks. Specific CARRC 1998B2007 accomplishments included: (1) Development of several ASTM International Standard Guides for CCB utilization applications. (2) Organization and presentation of training courses for CCB professionals and teachers. (3) Development of online resources including the Coal Ash Resource Center, Ash from Biomass in Coal (ABC) of cocombustion ash characteristics, and the Buyer's Guide to Coal-Ash Containing Products. In addition

Environmental Resource Management Issues in Agronomy: A Lecture/Laboratory Course

Science.gov (United States)

Munn, D. A.

2004-01-01

Environmental Sciences Technology T272 is a course with a laboratory addressing problems in soil and water quality and organic wastes utilization to serve students from associate degree programs in laboratory science and environmental resources management at a 2-year technical college. Goals are to build basic lab skills and understand the role…

The need for econometric research in laboratory animal operations.

Science.gov (United States)

Baker, David G; Kearney, Michael T

2015-06-01

The scarcity of research funding can affect animal facilities in various ways. These effects can be evaluated by examining the allocation of financial resources in animal facilities, which can be facilitated by the use of mathematical and statistical methods to analyze economic problems, a discipline known as econometrics. The authors applied econometrics to study whether increasing per diem charges had a negative effect on the number of days of animal care purchased by animal users. They surveyed animal numbers and per diem charges at 20 research institutions and found that demand for large animals decreased as per diem charges increased. The authors discuss some of the challenges involved in their study and encourage research institutions to carry out more robust econometric studies of this and other economic questions facing laboratory animal research.

Lawrence Berkeley Laboratory, Institutional Plan FY 1994--1999

Energy Technology Data Exchange (ETDEWEB)

1993-09-01

The Institutional Plan provides an overview of the Lawrence Berkeley Laboratory mission, strategic plan, scientific initiatives, research programs, environment and safety program plans, educational and technology transfer efforts, human resources, and facilities needs. For FY 1994-1999 the Institutional Plan reflects significant revisions based on the Laboratory`s strategic planning process. The Strategic Plan section identifies long-range conditions that will influence the Laboratory, as well as potential research trends and management implications. The Initiatives section identifies potential new research programs that represent major long-term opportunities for the Laboratory, and the resources required for their implementation. The Scientific and Technical Programs section summarizes current programs and potential changes in research program activity. The Environment, Safety, and Health section describes the management systems and programs underway at the Laboratory to protect the environment, the public, and the employees. The Technology Transfer and Education programs section describes current and planned programs to enhance the nation`s scientific literacy and human infrastructure and to improve economic competitiveness. The Human Resources section identifies LBL staff diversity and development program. The section on Site and Facilities discusses resources required to sustain and improve the physical plant and its equipment. The new section on Information Resources reflects the importance of computing and communication resources to the Laboratory. The Resource Projections are estimates of required budgetary authority for the Laboratory`s ongoing research programs. The Institutional Plan is a management report for integration with the Department of Energy`s strategic planning activities, developed through an annual planning process.

Laboratory directed research and development program FY 2003

Energy Technology Data Exchange (ETDEWEB)

Hansen, Todd

2004-03-27

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. In FY03, Berkeley Lab was authorized by DOE to establish a funding ceiling for the LDRD program of $15.0 M, which equates to about 3.2% of Berkeley Lab's FY03 projected operating and capital equipment budgets. This funding level was provided to develop new scientific ideas and opportunities and allow the Berkeley Lab Director an opportunity to initiate new directions. Budget constraints limited available resources, however, so only $10.1 M was expended for operating and $0.6 M for capital equipment (2.4% of actual Berkeley Lab FY03 costs). In FY03, scientists submitted 168 proposals, requesting over $24.2 M in operating funding. Eighty-two projects were funded, with awards ranging from $45 K to $500 K. These projects are summarized in Table 1.

Laboratory Directed Research and Development Program FY2004

Energy Technology Data Exchange (ETDEWEB)

Hansen, Todd C.

2005-03-22

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Goals that are codified in DOE's September 2003 Strategic Plan, with a primary focus on Advancing Scientific Understanding. For that goal, the Fiscal Year (FY) 2004 LDRD projects support every one of the eight strategies described in the plan. In addition, LDRD efforts support the goals of Investing in America's Energy Future (six of the fourteen strategies), Resolving the Environmental Legacy (four of the eight strategies), and Meeting National Security Challenges (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD supports Office of Science strategic plans, including the 20 year Scientific Facilities Plan and the draft Office of Science Strategic Plan. The research also

Chemical research at Argonne National Laboratory

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-04-01

Argonne National Laboratory is a research and development laboratory located 25 miles southwest of Chicago, Illinois. It has more than 200 programs in basic and applied sciences and an Industrial Technology Development Center to help move its technologies to the industrial sector. At Argonne, basic energy research is supported by applied research in diverse areas such as biology and biomedicine, energy conservation, fossil and nuclear fuels, environmental science, and parallel computer architectures. These capabilities translate into technological expertise in energy production and use, advanced materials and manufacturing processes, and waste minimization and environmental remediation, which can be shared with the industrial sector. The Laboratory`s technologies can be applied to help companies design products, substitute materials, devise innovative industrial processes, develop advanced quality control systems and instrumentation, and address environmental concerns. The latest techniques and facilities, including those involving modeling, simulation, and high-performance computing, are available to industry and academia. At Argonne, there are opportunities for industry to carry out cooperative research, license inventions, exchange technical personnel, use unique research facilities, and attend conferences and workshops. Technology transfer is one of the Laboratory`s major missions. High priority is given to strengthening U.S. technological competitiveness through research and development partnerships with industry that capitalize on Argonne`s expertise and facilities. The Laboratory is one of three DOE superconductivity technology centers, focusing on manufacturing technology for high-temperature superconducting wires, motors, bearings, and connecting leads. Argonne National Laboratory is operated by the University of Chicago for the U.S. Department of Energy.

Tritium research laboratory cleanup and transition project final report

International Nuclear Information System (INIS)

Johnson, A.J.

1997-02-01

This Tritium Research Laboratory Cleanup and Transition Project Final Report provides a high-level summary of this project's multidimensional accomplishments. Throughout this report references are provided for in-depth information concerning the various topical areas. Project related records also offer solutions to many of the technical and or administrative challenges that such a cleanup effort requires. These documents and the experience obtained during this effort are valuable resources to the DOE, which has more than 1200 other process contaminated facilities awaiting cleanup and reapplication or demolition

Laboratory Directed Research and Development Program FY 2007 Annual Report

International Nuclear Information System (INIS)

Sjoreen, Terrence P.

2008-01-01

The Oak Ridge National LaboratoryLaboratory Directed Research and Development (LDRD) program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries for all ORNL LDRD research activities supported during FY 2007. The associated FY 2007 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R and D) to support DOE's overarching mission to advance the national, economic, and energy security of the United States and promote scientific and technological innovation in support of that mission. As a national resource, the Laboratory also applies its capabilities and skills to specific needs of other federal agencies and customers through the DOE Work for Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at http://www.ornl.gov/. LDRD is a relatively small but vital DOE program that allows ORNL, as well as other DOE laboratories, to select a limited number of R and D projects for the purpose of: (1) maintaining the scientific and technical vitality of the Laboratory; (2) enhancing the Laboratory's ability to address future DOE missions; (3) fostering creativity and stimulating exploration of forefront science

Laboratory Directed Research and Development Program FY 2007 Annual Report

Energy Technology Data Exchange (ETDEWEB)

Sjoreen, Terrence P [ORNL

2008-04-01

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries for all ORNL LDRD research activities supported during FY 2007. The associated FY 2007 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and an internal evaluation of the program's management process. ORNL is a DOE multiprogram science, technology, and energy laboratory with distinctive capabilities in materials science and engineering, neutron science and technology, energy production and end-use technologies, biological and environmental science, and scientific computing. With these capabilities ORNL conducts basic and applied research and development (R&D) to support DOE's overarching mission to advance the national, economic, and energy security of the United States and promote scientific and technological innovation in support of that mission. As a national resource, the Laboratory also applies its capabilities and skills to specific needs of other federal agencies and customers through the DOE Work for Others (WFO) program. Information about the Laboratory and its programs is available on the Internet at http://www.ornl.gov/. LDRD is a relatively small but vital DOE program that allows ORNL, as well as other DOE laboratories, to select a limited number of R&D projects for the purpose of: (1) maintaining the scientific and technical vitality of the Laboratory; (2) enhancing the Laboratory's ability to address future DOE missions; (3) fostering creativity and stimulating

Antifungal susceptibility testing method for resource constrained laboratories

Directory of Open Access Journals (Sweden)

Khan S

2006-01-01

Full Text Available Purpose: In resource-constrained laboratories of developing countries determination of antifungal susceptibility testing by NCCLS/CLSI method is not always feasible. We describe herein a simple yet comparable method for antifungal susceptibility testing. Methods: Reference MICs of 72 fungal isolates including two quality control strains were determined by NCCLS/CLSI methods against fluconazole, itraconazole, voriconazole, amphotericin B and cancidas. Dermatophytes were also tested against terbinafine. Subsequently, on selection of optimum conditions, MIC was determined for all the fungal isolates by semisolid antifungal agar susceptibility method in Brain heart infusion broth supplemented with 0.5% agar (BHIA without oil overlay and results were compared with those obtained by reference NCCLS/CLSI methods. Results: Comparable results were obtained by NCCLS/CLSI and semisolid agar susceptibility (SAAS methods against quality control strains. MICs for 72 isolates did not differ by more than one dilution for all drugs by SAAS. Conclusions: SAAS using BHIA without oil overlay provides a simple and reproducible method for obtaining MICs against yeast, filamentous fungi and dermatophytes in resource-constrained laboratories.

Zebrafish Health Conditions in the China Zebrafish Resource Center and 20 Major Chinese Zebrafish Laboratories.

Science.gov (United States)

Liu, Liyue; Pan, Luyuan; Li, Kuoyu; Zhang, Yun; Zhu, Zuoyan; Sun, Yonghua

2016-07-01

In China, the use of zebrafish as an experimental animal in the past 15 years has widely expanded. The China Zebrafish Resource Center (CZRC), which was established in 2012, is becoming one of the major resource centers in the global zebrafish community. Large-scale use and regular exchange of zebrafish resources have put forward higher requirements on zebrafish health issues in China. This article reports the current aquatic infrastructure design, animal husbandry, and health-monitoring programs in the CZRC. Meanwhile, through a survey of 20 Chinese zebrafish laboratories, we also describe the current health status of major zebrafish facilities in China. We conclude that it is of great importance to establish a widely accepted health standard and health-monitoring strategy in the Chinese zebrafish research community.

Strategic establishment of an International Pharmacology Specialty Laboratory in a resource-limited setting.

Science.gov (United States)

Mtisi, Takudzwa J; Maponga, Charles; Monera-Penduka, Tsitsi G; Mudzviti, Tinashe; Chagwena, Dexter; Makita-Chingombe, Faithful; DiFranchesco, Robin; Morse, Gene D

2018-01-01

A growing number of drug development studies that include pharmacokinetic evaluations are conducted in regions lacking a specialised pharmacology laboratory. This necessitated the development of an International Pharmacology Specialty Laboratory (IPSL) in Zimbabwe. The aim of this article is to describe the development of an IPSL in Zimbabwe. The IPSL was developed collaboratively by the University of Zimbabwe and the University at Buffalo Center for Integrated Global Biomedical Sciences. Key stages included infrastructure development, establishment of quality management systems and collaborative mentorship in clinical pharmacology study design and chromatographic assay development and validation. Two high performance liquid chromatography instruments were donated by an instrument manufacturer and a contract research organisation. Laboratory space was acquired through association with the Zimbabwe national drug regulatory authority. Operational policies, standard operating procedures and a document control system were established. Scientists and technicians were trained in aspects relevant to IPSL operations. A high-performance liquid chromatography method for nevirapine was developed with the guidance of the Clinical Pharmacology Quality Assurance programme and approved by the assay method review programme. The University of Zimbabwe IPSL is engaged with the United States National Institute of Allergy and Infectious Diseases Division of AIDS research networks and is poised to begin drug assays and pharmacokinetic analyses. An IPSL has been successfully established in a resource-limited setting through the efforts of an external partnership providing technical guidance and motivated internal faculty and staff. Strategic partnerships were beneficial in navigating challenges leading to laboratory development and training new investigators. The IPSL is now engaged in clinical pharmacology research.

Laboratory for Large Data Research

Data.gov (United States)

Federal Laboratory Consortium — FUNCTION: The Laboratory for Large Data Research (LDR) addresses a critical need to rapidly prototype shared, unified access to large amounts of data across both the...

The National Fire Research Laboratory

Data.gov (United States)

Federal Laboratory Consortium — The National Fire Research Laboratory (NFRL) is adding a unique facility that will serve as a center of excellence for fireperformance of structures ranging in size...

Establishment of a Laboratory for Biofuels Research at the University of Kentucky

Energy Technology Data Exchange (ETDEWEB)

Crocker, Mark [Univ. of Kentucky, Lexington, KY (United States). Center for Applied Energy Research; Crofcheck, Czarena [Univ. of Kentucky, Lexington, KY (United States). Center for Applied Energy Research; Andrews, Rodney [Univ. of Kentucky, Lexington, KY (United States). Center for Applied Energy Research

2013-03-29

This project was aimed at the development of the biofuels industry in Kentucky by establishing a laboratory to develop improved processes for biomass utilization. The facility is based at the University of Kentucky Center for Applied Energy Research and the Department of Biosystems and Agricultural Engineering, and constitutes an “open” laboratory, i.e., its equipment is available to other Kentucky researchers working in the area. The development of this biofuels facility represents a significant expansion of research infrastructure, and will provide a lasting resource for biobased research endeavors at the University of Kentucky. In order to enhance the laboratory's capabilities and contribute to on-going biofuels research at the University of Kentucky, initial research at the laboratory has focused on the following technical areas: (i) the identification of algae strains suitable for oil production, utilizing flue gas from coal-fired power plants as a source of CO₂; (ii) the conversion of algae to biofuels; and (iii) the development of methods for the analysis of lignin and its deconstruction products. Highlights from these activities include the development of catalysts for the upgrading of lipids to hydrocarbons by means of decarboxylation/decarbonylation (deCOx), a study of bio-oil production from the fast pyrolysis of algae (Scenedesmus), and the application of pyrolytic gas chromatography coupled with mass spectrometry (Py-GC-MS) to the characterization of high lignin biomass feedstocks.

Laboratory Directed Research and Development FY2011 Annual Report

International Nuclear Information System (INIS)

Craig, W.; Sketchley, J.; Kotta, P.

2012-01-01

A premier applied-science laboratory, Lawrence Livermore National Laboratory (LLNL) has earned the reputation as a leader in providing science and technology solutions to the most pressing national and global security problems. The LDRD Program, established by Congress at all DOE national laboratories in 1991, is LLNL's most important single resource for fostering excellent science and technology for today's needs and tomorrow's challenges. The LDRD internally directed research and development funding at LLNL enables high-risk, potentially high-payoff projects at the forefront of science and technology. The LDRD Program at Livermore serves to: (1) Support the Laboratory's missions, strategic plan, and foundational science; (2) Maintain the Laboratory's science and technology vitality; (3) Promote recruiting and retention; (4) Pursue collaborations; (5) Generate intellectual property; and (6) Strengthen the U.S. economy. Myriad LDRD projects over the years have made important contributions to every facet of the Laboratory's mission and strategic plan, including its commitment to nuclear, global, and energy and environmental security, as well as cutting-edge science and technology and engineering in high-energy-density matter, high-performance computing and simulation, materials and chemistry at the extremes, information systems, measurements and experimental science, and energy manipulation. A summary of each project was submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to DOE/NNSA and LLNL mission areas, the technical progress achieved in FY11, and a list of publications that resulted from the research. The projects are: (1) Nuclear Threat Reduction; (2) Biosecurity; (3) High-Performance Computing and Simulation; (4) Intelligence; (5) Cybersecurity; (6) Energy Security; (7) Carbon Capture; (8) Material Properties, Theory, and Design; (9) Radiochemistry; (10) High-Energy-Density Science; (11) Laser Inertial

The Advanced Labs Website: resources for upper-level laboratories

Science.gov (United States)

Torres-Isea, Ramon

2012-03-01

The Advanced Labs web resource collection is an effort to create a central, comprehensive information base for college/university faculty who teach upper-level undergraduate laboratories. The website is produced by the American Association of Physics Teachers (AAPT). It is a part of ComPADRE, the online collection of resources in physics and astronomy education, which itself is a part of the National Science Foundation-funded National Science Digital Library (NSDL). After a brief review of its history, we will discuss the current status of the website while describing the various types of resources available at the site and presenting examples of each. We will detail a step-by-step procedure for submitting resources to the website. The resource collection is designed to be a community effort and thus welcomes input and contributions from its users. We will also present plans, and will seek audience feedback, for additional website services and features. The constraints, roadblocks, and rewards of this project will also be addressed.

Laboratory Directed Research ampersand Development Program

International Nuclear Information System (INIS)

Ogeka, G.J.; Romano, A.J.

1993-12-01

At Brookhaven National Laboratory the Laboratory Directed Research and Development (LDRD) Program is a discretionary research and development tool critical in maintaining the scientific excellence and vitality of the laboratory. It is also a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor in achieving and maintaining staff excellence, and a means to address national needs, within the overall mission of the Department of Energy and Brookhaven National Laboratory. This report summarizes research which was funded by this program during fiscal year 1993. The research fell in a number of broad technical and scientific categories: new directions for energy technologies; global change; radiation therapies and imaging; genetic studies; new directions for the development and utilization of BNL facilities; miscellaneous projects. Two million dollars in funding supported 28 projects which were spread throughout all BNL scientific departments

CULTURAL RESOURCE MANAGEMENT PLAN FOR BROOKHAVEN NATIONAL LABORATORY.

Energy Technology Data Exchange (ETDEWEB)

DAVIS, M.

2005-04-01

The Cultural Resource Management Plan (CRMP) for Brookhaven National Laboratory (BNL) provides an organized guide that describes or references all facets and interrelationships of cultural resources at BNL. This document specifically follows, where applicable, the format of the U.S. Department of Energy (DOE) Environmental Guidelines for Development of Cultural Resource Management Plans, DOE G 450.1-3 (9-22-04[m1]). Management strategies included within this CRMP are designed to adequately identify the cultural resources that BNL and DOE consider significant and to acknowledge associated management actions. A principal objective of the CRMP is to reduce the need for additional regulatory documents and to serve as the basis for a formal agreement between the DOE and the New York State Historic Preservation Officer (NYSHPO). The BNL CRMP is designed to be a ''living document.'' Each section includes identified gaps in the management plan, with proposed goals and actions for addressing each gap. The plan will be periodically revised to incorporate new documentation.

Pacific Northwest Laboratory annual report for 1990 to the DOE Office of Energy Research

Energy Technology Data Exchange (ETDEWEB)

Park, J. F.; Kreml, S. A.; Wildung, R. E.; Hefty, M. G.; Perez, D. A.; Chase, K. K.; Elderkin, C. E.; Owczarski, E. L.; Toburen, L. H.; Parnell, K. A.; Faust, L. G.; Moraski, R. V.; Selby, J. M.; Hilliard, D. K.; Tenforde, T. S.

1991-02-01

This report summarizes progress in the environmental sciences research conducted by Pacific Northwest Laboratory (PNL) for the Office of Health and Environment Research in FY 1990. Research is directed toward developing the knowledge needed to guide government policy and technology development for two important environmental problems: environmental restoration and global change. The report is organized by major research areas contributing to resolution of these problems. Additional sections summarize exploratory research, educational institutional interactions, technology transfer, and publications. The PNL research program continues make contributions toward defining and quantifying processes that effect the environment at the local, regional, and global levels. Each research project forms a component in an integrated laboratory, intermediate-scale, and field approach designed to examine multiple phenomena at increasing levels of complexity. This approach is providing system-level insights into critical environmental processes. University liaisons continue to be expanded to strengthen the research and to use PNL resources to train the scientists needed to address long-term environmental problems.

Fuel Combustion Laboratory | Transportation Research | NREL

Science.gov (United States)

Fuel Combustion Laboratory Fuel Combustion Laboratory NREL's Fuel Combustion Laboratory focuses on designs, using both today's technology and future advanced combustion concepts. This lab supports the combustion chamber platform for fuel ignition kinetics research, was acquired to expand the lab's

A university hot laboratory for teaching and research

International Nuclear Information System (INIS)

Heinonen, O.; Miettinen, J.K.

1976-01-01

In small countries which have limited material and capital resources there is more need for studying and teaching reactor chemistry in universities than there is in countries with special nuclear research and training centres. A new 150-m 2 laboratory of reactor chemistry was added to the premises of the Department of Radiochemistry, University of Helsinki, in October 1975. It contains a hot area with low-pressure air-conditioning, a sanitary room, a low-activity area, and an office area. The main instrument is a mass-spectrometer MI-1309 equipped with an ion counter which is particularly useful for plutonium analysis. The laboratory can handle samples up-to 10Ci gamma-acitivity - which equals one pellet of a fuel rod - in a sealed lead cell which has an interchangeable box for alpha-active work. Pretreated samples are submitted to chemical separations in glove-boxes. Samples for alpha and mass spectroscopy are also prepared in glove-boxes. Also the laboratory is provided with fume hoods suitable for building lead shields. Radiation protection and special features typical to the university environment are discussed. Methods for verfication of contamination and protection against internal and external contamination are applied. These include air monitoring, analysis of excreta, and whole-body counting. (author)

Network Science Research Laboratory (NSRL) Discrete Event Toolkit

Science.gov (United States)

2016-01-01

ARL-TR-7579 ● JAN 2016 US Army Research Laboratory Network Science Research Laboratory (NSRL) Discrete Event Toolkit by...Laboratory (NSRL) Discrete Event Toolkit by Theron Trout and Andrew J Toth Computational and Information Sciences Directorate, ARL...Research Laboratory (NSRL) Discrete Event Toolkit 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Theron Trout

NAS Human Factors Safety Research Laboratory

Data.gov (United States)

Federal Laboratory Consortium — This laboratory conducts an integrated program of research on the relationship of factors concerning individuals, work groups, and organizations as employees perform...

How Fifth Grade Latino/a Bilingual Students Use Their Linguistic Resources in the Classroom and Laboratory during Science Instruction

Science.gov (United States)

Stevenson, Alma R.

2013-01-01

This qualitative, sociolinguistic research study examines how bilingual Latino/a students use their linguistic resources in the classroom and laboratory during science instruction. This study was conducted in a school in the southwestern United States serving an economically depressed, predominantly Latino population. The object of study was a…

Building an integrated nuclear engineering and nuclear science human resources pipeline at the Idaho National Engineering and Environmental Laboratory

International Nuclear Information System (INIS)

Sneed, A.; Sikorski, B.; Lineberry, M.; Jolly, J.

2004-01-01

In a joint effort with the Argonne National Laboratory - West (ANL-W), the Idaho National Engineering and Environmental Laboratory (INEEL) has assumed the lead role for nuclear energy reactor research for the United States Government. In 2005, these two laboratories will be combined into one entity, the Idaho National Laboratory (INL). There are two objectives for the INL: (1) to act as the lead systems integrator for the Department of Energy's Office of Nuclear Energy Science and Technology and, (2) to establish a Center for Advanced Energy Studies. Focusing on the Center for Advanced Energy Studies, this paper presents a Human Resources Pipeline Model outlining a nuclear educational pathway that leads to university and industry research partnerships. The pathway progresses from education to employment and into retirement. Key to the model is research and mentoring and their impact upon each stage. The Center's success will be the result of effective and advanced communications, faculty/student involvement, industry support, inclusive broadbased involvement, effective long-term partnering, and increased federal and state support. (author)

Building an integrated nuclear engineering and nuclear science human resources pipeline at the Idaho National Engineering and Environmental Laboratory

International Nuclear Information System (INIS)

Sneed, A.; Sikorski, B.; Lineberry, M.; Jolly, J.

2004-01-01

Full text: In 2002, the US Department of Energy (US DOE) transferred sponsorship of the INEEL and ANL-W to the DOE Office of Nuclear Energy, Science and Technology and designated the INEEL and ANL-W as the nation's lead laboratories for nuclear reactor and nuclear fuel cycle research and development. This transfer acknowledged the laboratories' history, infrastructure, expertise and commitment to collaborate broadly in order to fulfill its assigned role as the nation's center for nuclear energy research and development. Key to this role is the availability of well-educated and trained nuclear engineers, professionals from other disciplines of engineering, nuclear scientists, and others with advanced degrees in supporting disciplines such as physics, chemistry, and math. In 2005 the INEEL and ANL-W will be combined into the Idaho National Laboratory (INL). One of US DOE's objectives for the INL will be for it to take a strong role in the revitalization of nuclear engineering and nuclear science education in the US. Responding to this objective for the INL and the national need to rejuvenate nuclear engineering and nuclear science research and education, ISU, University of Idaho (UI), Boise State University, the INEEL, and ANL-W are all supporting a new Institute of Nuclear Science and Engineering (INSE), initially proposed by and to be administered by ISU. The Institute will rely on the resources of both universities and the INL to create a US center for reactor and fuel cycle research to development and attract outstanding faculty and students to Idaho and to the INL. The Institute and other university based education development efforts represent only one component of a viable Human Resources Pipeline from university to leading edge laboratory researcher. Another critical component is the successful integration of new graduates into the laboratory research environment, the transfer of knowledge from senior researchers, and the development of these individuals into

Genome resource banking of biomedically important laboratory animals.

Science.gov (United States)

Agca, Yuksel

2012-11-01

Genome resource banking is the systematic collection, storage, and redistribution of biomaterials in an organized, logistical, and secure manner. Genome cryobanks usually contain biomaterials and associated genomic information essential for progression of biomedicine, human health, and research. In that regard, appropriate genome cryobanks could provide essential biomaterials for both current and future research projects in the form of various cell types and tissues, including sperm, oocytes, embryos, embryonic or adult stem cells, induced pluripotent stem cells, and gonadal tissues. In addition to cryobanked germplasm, cryobanking of DNA, serum, blood products, and tissues from scientifically, economically, and ecologically important species has become a common practice. For revitalization of the whole organism, cryopreserved germplasm in conjunction with assisted reproductive technologies, offer a powerful approach for research model management, as well as assisting in animal production for agriculture, conservation, and human reproductive medicine. Recently, many developed and developing countries have allocated substantial resources to establish genome resources banks which are responsible for safeguarding scientifically, economically, and ecologically important wild type, mutant, and transgenic plants, fish, and local livestock breeds, as well as wildlife species. This review is dedicated to the memory of Dr. John K. Critser, who has made profound contributions to the science of cryobiology and establishment of genome research and resources centers for mice, rats, and swine. Emphasis will be given to application of genome resource banks to species with substantial contributions to the advancement of biomedicine and human health. Copyright © 2012 Elsevier Inc. All rights reserved.

Idaho National Laboratory Cultural Resource Management Annual Report FY 2006

Energy Technology Data Exchange (ETDEWEB)

Clayton F. Marler; Julie Braun; Hollie Gilbert; Dino Lowrey; Brenda Ringe Pace

2007-04-01

The Idaho National Laboratory Site is home to vast numbers and a wide variety of important cultural resources representing at least a 13,500-year span of human occupation in the region. As a federal agency, the Department of Energy Idaho Operations Office has legal responsibility for the management and protection of those resources and has delegated these responsibilities to its primary contractor, Battelle Energy Alliance (BEA). The INL Cultural Resource Management Office, staffed by BEA professionals, is committed to maintaining a cultural resource management program that accepts these challenges in a manner reflecting the resources’ importance in local, regional, and national history. This annual report summarizes activities performed by the INL Cultural Resource Management Office staff during Fiscal Year 2006. This work is diverse, far-reaching and though generally confined to INL cultural resource compliance, also includes a myriad of professional and voluntary community activities. This document is intended to be both informative to internal and external stakeholders, and to serve as a planning tool for future cultural resource management work to be conducted on the INL.

Laboratory Directed Research and Development FY2011 Annual Report

Energy Technology Data Exchange (ETDEWEB)

Craig, W; Sketchley, J; Kotta, P

2012-03-22

A premier applied-science laboratory, Lawrence Livermore National Laboratory (LLNL) has earned the reputation as a leader in providing science and technology solutions to the most pressing national and global security problems. The LDRD Program, established by Congress at all DOE national laboratories in 1991, is LLNL's most important single resource for fostering excellent science and technology for today's needs and tomorrow's challenges. The LDRD internally directed research and development funding at LLNL enables high-risk, potentially high-payoff projects at the forefront of science and technology. The LDRD Program at Livermore serves to: (1) Support the Laboratory's missions, strategic plan, and foundational science; (2) Maintain the Laboratory's science and technology vitality; (3) Promote recruiting and retention; (4) Pursue collaborations; (5) Generate intellectual property; and (6) Strengthen the U.S. economy. Myriad LDRD projects over the years have made important contributions to every facet of the Laboratory's mission and strategic plan, including its commitment to nuclear, global, and energy and environmental security, as well as cutting-edge science and technology and engineering in high-energy-density matter, high-performance computing and simulation, materials and chemistry at the extremes, information systems, measurements and experimental science, and energy manipulation. A summary of each project was submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to DOE/NNSA and LLNL mission areas, the technical progress achieved in FY11, and a list of publications that resulted from the research. The projects are: (1) Nuclear Threat Reduction; (2) Biosecurity; (3) High-Performance Computing and Simulation; (4) Intelligence; (5) Cybersecurity; (6) Energy Security; (7) Carbon Capture; (8) Material Properties, Theory, and Design; (9) Radiochemistry; (10) High

Laboratory Animal Sciences Program (LASP)

Data.gov (United States)

Federal Laboratory Consortium — The Laboratory Animal Sciences Program (LASP) is a comprehensive resource for scientists performing animal-based research to gain a better understanding of cancer,...

Green Building Research Laboratory

Energy Technology Data Exchange (ETDEWEB)

Sailor, David Jean [Portland State Univ., Portland, OR (United States)

2013-12-29

This project provided support to the Green Building Research Laboratory at Portland State University (PSU) so it could work with researchers and industry to solve technical problems for the benefit of the green building industry. It also helped to facilitate the development of PSU’s undergraduate and graduate-level training in building science across the curriculum.

Laboratory Technology Research: Abstracts of FY 1996 projects

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-12-31

The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of this country: the world-class basic research capability of the DOE Energy Research (ER) multi-program national laboratories and the unparalleled entrepreneurial spirit of American industry. Projects supported by the LTR program are conducted by the five ER multi-program laboratories: Argonne, Brookhaven, Lawrence Berkeley, Oak Ridge, and Pacific Northwest National Laboratories. These projects explore the applications of basic research advances relevant to Department of Energy`s (DOE) mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials, intelligent processing/manufacturing research, and sustainable environments.

Lawrence Berkeley Laboratory Institutional Plan, FY 1993--1998

Energy Technology Data Exchange (ETDEWEB)

Chew, Joseph T.; Stroh, Suzanne C.; Maio, Linda R.; Olson, Karl R.; Grether, Donald F.; Clary, Mary M.; Smith, Brian M.; Stevens, David F.; Ross, Loren; Alper, Mark D.; Dairiki, Janis M.; Fong, Pauline L.; Bartholomew, James C.

1992-10-01

The FY 1993--1998 Institutional Plan provides an overview of the Lawrence Berkeley Laboratory mission, strategic plan, scientific initiatives, research programs, environment and safety program plans, educational and technology transfer efforts, human resources, and facilities needs. The Strategic Plan section identifies long-range conditions that can influence the Laboratory, potential research trends, and several management implications. The Initiatives section identifies potential new research programs that represent major long-term opportunities for the Laboratory and the resources required for their implementation. The Scientific and Technical Programs section summarizes current programs and potential changes in research program activity. The Environment, Safety, and Health section describes the management systems and programs underway at the Laboratory to protect the environment, the public, and the employees. The Technology Transfer and Education programs section describes current and planned programs to enhance the nation`s scientific literacy and human infrastructure and to improve economic competitiveness. The Human Resources section identifies LBL staff composition and development programs. The section on Site and Facilities discusses resources required to sustain and improve the physical plant and its equipment. The Resource Projections are estimates of required budgetary authority for the Laboratory`s ongoing research programs. The plan is an institutional management report for integration with the Department of Energy`s strategic planning activities that is developed through an annual planning process. The plan identifies technical and administrative directions in the context of the National Energy Strategy and the Department of Energy`s program planning initiatives. Preparation of the plan is coordinated by the Office for Planning and Development from information contributed by the Laboratory`s scientific and support divisions.

The underground research laboratories

International Nuclear Information System (INIS)

1997-06-01

This educational booklet is a general presentation of the selected sites for the installation of underground research laboratories devoted to the feasibility studies of deep repositories for long-life radioactive wastes. It describes the different type of wastes and their management, the management of long life radioactive wastes, the site selection and the 4 sites retained, the preliminary research studies, and the other researches carried out in deep disposal facilities worldwide. (J.S.)

Techniques in cancer research: a laboratory manual

International Nuclear Information System (INIS)

Deo, M.G.; Seshadri, R.; Mulherkar, R.; Mukhopadhyaya, R.

1995-01-01

Cancer Research Institute (CRI) works on all facets of cancer using the latest biomedical tools. For this purpose, it has established modern laboratories in different branches of cancer biology such as cell and molecular biology, biochemistry, immunology, chemical and viral oncogenesis, genetics of cancer including genetic engineering, tissue culture, cancer chemotherapy, neurooncology and comparative oncology. This manual describes the protocols used in these laboratories. There is also a chapter on handling and care of laboratory animals, an essential component of any modern cancer biology laboratory. It is hoped that the manual will be useful to biomedical laboratories, specially those interested in cancer research. refs., tabs., figs

Argonne National Laboratory annual report of Laboratory Directed Research and Development Program Activities FY 2009.

Energy Technology Data Exchange (ETDEWEB)

Office of the Director

2010-04-09

I am pleased to submit Argonne National Laboratory's Annual Report on its Laboratory Directed Research and Development (LDRD) activities for fiscal year 2009. Fiscal year 2009 saw a heightened focus by DOE and the nation on the need to develop new sources of energy. Argonne scientists are investigating many different sources of energy, including nuclear, solar, and biofuels, as well as ways to store, use, and transmit energy more safely, cleanly, and efficiently. DOE selected Argonne as the site for two new Energy Frontier Research Centers (EFRCs) - the Institute for Atom-Efficient Chemical Transformations and the Center for Electrical Energy Storage - and funded two other EFRCs to which Argonne is a major partner. The award of at least two of the EFRCs can be directly linked to early LDRD-funded efforts. LDRD has historically seeded important programs and facilities at the lab. Two of these facilities, the Advanced Photon Source and the Center for Nanoscale Materials, are now vital contributors to today's LDRD Program. New and enhanced capabilities, many of which relied on LDRD in their early stages, now help the laboratory pursue its evolving strategic goals. LDRD has, since its inception, been an invaluable resource for positioning the Laboratory to anticipate, and thus be prepared to contribute to, the future science and technology needs of DOE and the nation. During times of change, LDRD becomes all the more vital for facilitating the necessary adjustments while maintaining and enhancing the capabilities of our staff and facilities. Although I am new to the role of Laboratory Director, my immediate prior service as Deputy Laboratory Director for Programs afforded me continuous involvement in the LDRD program and its management. Therefore, I can attest that Argonne's program adhered closely to the requirements of DOE Order 413.2b and associated guidelines governing LDRD. Our LDRD program management continually strives to be more efficient. In

Argonne National Laboratory annual report of Laboratory Directed Research and Development Program Activities FY 2009

International Nuclear Information System (INIS)

2010-01-01

I am pleased to submit Argonne National Laboratory's Annual Report on its Laboratory Directed Research and Development (LDRD) activities for fiscal year 2009. Fiscal year 2009 saw a heightened focus by DOE and the nation on the need to develop new sources of energy. Argonne scientists are investigating many different sources of energy, including nuclear, solar, and biofuels, as well as ways to store, use, and transmit energy more safely, cleanly, and efficiently. DOE selected Argonne as the site for two new Energy Frontier Research Centers (EFRCs) - the Institute for Atom-Efficient Chemical Transformations and the Center for Electrical Energy Storage - and funded two other EFRCs to which Argonne is a major partner. The award of at least two of the EFRCs can be directly linked to early LDRD-funded efforts. LDRD has historically seeded important programs and facilities at the lab. Two of these facilities, the Advanced Photon Source and the Center for Nanoscale Materials, are now vital contributors to today's LDRD Program. New and enhanced capabilities, many of which relied on LDRD in their early stages, now help the laboratory pursue its evolving strategic goals. LDRD has, since its inception, been an invaluable resource for positioning the Laboratory to anticipate, and thus be prepared to contribute to, the future science and technology needs of DOE and the nation. During times of change, LDRD becomes all the more vital for facilitating the necessary adjustments while maintaining and enhancing the capabilities of our staff and facilities. Although I am new to the role of Laboratory Director, my immediate prior service as Deputy Laboratory Director for Programs afforded me continuous involvement in the LDRD program and its management. Therefore, I can attest that Argonne's program adhered closely to the requirements of DOE Order 413.2b and associated guidelines governing LDRD. Our LDRD program management continually strives to be more efficient. In addition to

Research programs at the Department of Energy National Laboratories. Volume 2: Laboratory matrix

Energy Technology Data Exchange (ETDEWEB)

NONE

1994-12-01

For nearly fifty years, the US national laboratories, under the direction of the Department of Energy, have maintained a tradition of outstanding scientific research and innovative technological development. With the end of the Cold War, their roles have undergone profound changes. Although many of their original priorities remain--stewardship of the nation`s nuclear stockpile, for example--pressing budget constraints and new federal mandates have altered their focus. Promotion of energy efficiency, environmental restoration, human health, and technology partnerships with the goal of enhancing US economic and technological competitiveness are key new priorities. The multiprogram national laboratories offer unparalleled expertise in meeting the challenge of changing priorities. This volume aims to demonstrate each laboratory`s uniqueness in applying this expertise. It describes the laboratories` activities in eleven broad areas of research that most or all share in common. Each section of this volume is devoted to a single laboratory. Those included are: Argonne National Laboratory; Brookhaven National Laboratory; Idaho National Engineering Laboratory; Lawrence Berkeley Laboratory; Lawrence Livermore National Laboratory; Los Alamos National Laboratory; National Renewable Energy Laboratory; Oak Ridge National Laboratory; Pacific Northwest Laboratory; and Sandia National Laboratories. The information in this volume was provided by the multiprogram national laboratories and compiled at Lawrence Berkeley Laboratory.

Hanford Cultural Resources Laboratory annual report for fiscal year 1989

Energy Technology Data Exchange (ETDEWEB)

Chatters, J.C.; Cadoret, N.A.; Minthorn, P.E.

1990-06-01

This report summarizes activities of the Hanford Cultural Resources Laboratory (HCRL) during fiscal year 1989. The HCRL provides support for managing the archaeological, historical, and cultural resources of the Hanford Site, Washington, in a manner consistent with the National Historic Preservation Act of 1966, the Archaeological Resources Protection Act of 1979, and the American Indian Religious Freedom Act of 1978. A major task in FY 1989 was completion and publication of the Hanford Cultural Resources Management Plan, which prioritizes tasks to be undertaken to bring the US Department of Energy -- Richland Operations into compliance with federal statutes, relations, and guidelines. During FY 1989, six tasks were performed. In order of priority, these were conducting 107 cultural resource reviews, monitoring the condition of 40 known prehistoric archaeological sites, assessing the condition of artifact collections from the Hanford Site, evaluating three sites and nominating two of those to the National Register of Historic Places, developing an education program and presenting 11 lectures to public organizations, and surveying approximately 1 mi{sup 2} of the Hanford Site for cultural resources. 7 refs., 4 figs., 4 tabs.

Idaho National Laboratory Cultural Resource Management Annual Report FY 2007

Energy Technology Data Exchange (ETDEWEB)

Julie Braun; Hollie Gilbert; Dino Lowrey; Clayton Marler; Brenda Pace

2008-03-01

The Idaho National Laboratory (INL) Site is home to vast numbers and a wide variety of important cultural resources representing at least a 13,500-year span of human land use in the region. As a federal agency, the Department of Energy Idaho Operations Office has legal responsibility for the management and protection of those resources and has delegated these responsibilities to its primary contractor, Battelle Energy Alliance (BEA). The BEA professional staff is committed to maintaining a cultural resource management program that accepts these challenges in a manner reflecting the resources’ importance in local, regional, and national history. This annual report summarizes activities performed by the INL Cultural Resource Management Office (CRMO) staff during fiscal year 2007. This work is diverse, far-reaching and though generally confined to INL cultural resource compliance, also includes a myriad of professional and voluntary community activities. This document is intended to be both informative to internal and external stakeholders, and to serve as a planning tool for future cultural resource management work to be conducted on the INL.

Pacific Northwest Laboratory annual report for 1993 to the DOE Office of Energy Research. Part 2: Environmental sciences

Energy Technology Data Exchange (ETDEWEB)

1994-04-01

This 1993 Annual Report from Pacific Northwest Laboratory (PNL) to the US DOE describes research in environment and health conducted during fiscal year (FY) 1993. The report is divided into four parts, each in a separate volume. This part, Volume 2, covers Environmental Sciences. The research is directed toward developing a fundamental understanding of subsurface and terrestrial systems as a basis for both managing these critical resources and addressing environmental problems such as environmental restoration and global change. There are sections on Subsurface Science, Terrestrial Science, Technology Transfer, Interactions with Educational Institutions, and Laboratory Directed Research and Development.

Hanford Cultural Resources Laboratory annual report for fiscal year 1994

International Nuclear Information System (INIS)

Nickens, P.R.; Wright, M.K.; Cadoret, N.A.; Dawson, M.V.; Harvey, D.W.; Simpson, E.M.

1995-09-01

The Hanford Site occupies 560 sq. miles of land along the Columbia River in SE Washington. The Hanford Reach of the river is one of the most archaeologically rich areas in the western Columbia Plateau. To manage the Hanford Site's archaeological, historical, and cultural resources, the Hanford Cultural Resources Laboratory (HCRL) was established in 1987. HCRL ensures DOE complies with federal statutes, regulations, and guidelines. In FY 1994, HCRL conducted cultural resource reviews, conducted programs to identify and monitor historic and archaeological sites, etc. HCRL staff conducted 511 reviews, 29 of which required archaeological surveys and 10 of which required building documentation. Six prehistoric sites, 23 historic sites, one paleontological site, and two sites with historic and prehistoric components were discovered

Hanford Cultural Resources Laboratory annual report for fiscal year 1994

Energy Technology Data Exchange (ETDEWEB)

Nickens, P.R.; Wright, M.K.; Cadoret, N.A.; Dawson, M.V.; Harvey, D.W.; Simpson, E.M.

1995-09-01

The Hanford Site occupies 560 sq. miles of land along the Columbia River in SE Washington. The Hanford Reach of the river is one of the most archaeologically rich areas in the western Columbia Plateau. To manage the Hanford Site`s archaeological, historical, and cultural resources, the Hanford Cultural Resources Laboratory (HCRL) was established in 1987. HCRL ensures DOE complies with federal statutes, regulations, and guidelines. In FY 1994, HCRL conducted cultural resource reviews, conducted programs to identify and monitor historic and archaeological sites, etc. HCRL staff conducted 511 reviews, 29 of which required archaeological surveys and 10 of which required building documentation. Six prehistoric sites, 23 historic sites, one paleontological site, and two sites with historic and prehistoric components were discovered.

Annual Report FY2011: Establishment of a Laboratory for Biofuels Research at the University of Kentucky

Energy Technology Data Exchange (ETDEWEB)

Crocker, Mark [Univ. of Kentucky, Lexington, KY (United States). Center for Applied Energy Research; Crofcheck, Czarena [Univ. of Kentucky, Lexington, KY (United States). Center for Applied Energy Research; Andrews, Rodney [Univ. of Kentucky, Lexington, KY (United States). Center for Applied Energy Research

2011-12-21

This project is aimed at the development of the biofuels industry in Kentucky by establishing a laboratory to develop improved processes for biomass utilization. The facility is based at the University of Kentucky Center for Applied Energy Research and the Department of Biosystems and Agricultural Engineering, and constitutes an open laboratory, i.e., its equipment is available to other Kentucky researchers working in the area. The development of this biofuels facility represents a significant expansion of research infrastructure, and will provide a lasting resource for biobased research endeavors at the University of Kentucky. In order to enhance the laboratory's capabilities and contribute to on-going biofuels research at the University of Kentucky, initial research at the laboratory has focused on the following technical areas: (i) the identification of algae strains suitable for oil production, utilizing flue gas from coal-fired power plants as a source of CO₂; (ii) the conversion of algae to biofuels; and (iii) thermochemical methods for the deconstruction of lignin. Highlights from these activities include a detailed study of bio-oil production from the fast pyrolysis of microalgae (Scenedesmus sp.) and the application of pyrolytic gas chromatography coupled with mass spectrometry (Py-GC-MS) to the characterization of high lignin biomass feedstocks.

The Swedish Research Councils' Laboratory progress report for 1975

International Nuclear Information System (INIS)

Rudstam, G.

1976-01-01

The Swedish Research Councils' Laboratory herewith presents its progress report for 1975. The report summarizes the current projects carried out by the research groups working at the laboratory. The very efficient assistance of the staff of the laboratory is greatfully acknowledged. The laboratory has been financially supported by the Atomic Research Council, the Medical Research Council, the Natural Science Research Council, and the Board of Technical Development. Valuable support in various ways has also been given by the Atomic Energy Company (AB Atomenergi). (author)

Provincial resource development research policy

Energy Technology Data Exchange (ETDEWEB)

Flock, D L

1976-01-01

In Alberta, there is an abundance of oil, natural gas, and coal. But only a small portion of the Alberta oil sands and coal resources are commercially accessible to surface-mining techniques. It is quite apparent that some in-situ technological breakthrough will be required, which will mean a concerted research effort at the provincial level. It is the purpose of this paper to present certain concepts and recommendations for a coordinated provincial resource development research policy for the Province of Alberta. Research as discussed in this paper covers basic and applied research and development. (MCW)

Resources | IDRC - International Development Research Centre

International Development Research Centre (IDRC) Digital Library (Canada)

Through IDRC's resource library, we share our results, provide support to ... Our Research Support team provides the resources and tools researchers need to ... It also includes information on how to structure and design your policy brief to ...

Argonne Research Library | Argonne National Laboratory

Science.gov (United States)

Argonne Argonne Research Library The Argonne Research Library supports the scientific and technical research needs of Argonne National Laboratory employees. Our library catalog is available via the Research questions or concerns, please contact us at librarians@anl.gov. Contact the Library Argonne Research Library

Physics Research at the Naval Research Laboratory

Science.gov (United States)

Coffey, Timothy

2001-03-01

The United States Naval Research Laboratory conducts a broad program of research into the physical properties of matter. Studies range from low temperature physics, such as that associated with superconducting systems to high temperature systems such as laser produced or astrophysical plasmas. Substantial studies are underway on surface science and nanoscience. Studies are underway on the electronic and optical properties of materials. Studies of the physical properties of the ocean and the earth’s atmosphere are of considerable importance. Studies of the earth’s sun particularly as it effects the earth’s ionosphere and magnetosphere are underway. The entire program involves a balance of laboratory experiments, field experiments and supporting theoretical and computational studies. This talk will address NRL’s funding of physics, its employment of physicists and will illustrate the nature of NRL’s physics program with several examples of recent accomplishments.

A Research-Based Laboratory Course Designed to Strengthen the Research-Teaching Nexus

Science.gov (United States)

Parra, Karlett J.; Osgood, Marcy P.; Pappas, Donald L., Jr.

2010-01-01

We describe a 10-week laboratory course of guided research experiments thematically linked by topic, which had an ultimate goal of strengthening the undergraduate research-teaching nexus. This undergraduate laboratory course is a direct extension of faculty research interests. From DNA isolation, characterization, and mutagenesis, to protein…

Laboratory technology research - abstracts of FY 1997 projects

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-11-01

The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of this country: the world-class basic research capability of the DOE Energy Research (ER) multi-program national laboratories and the unparalleled entrepreneurial spirit of American industry. A distinguishing feature of the ER multi-program national laboratories is their ability to integrate broad areas of science and engineering in support of national research and development goals. The LTR program leverages this strength for the Nation`s benefit by fostering partnerships with US industry. The partners jointly bring technology research to a point where industry or the Department`s technology development programs can pursue final development and commercialization. Projects supported by the LTR program are conducted by the five ER multi-program laboratories. These projects explore the applications of basic research advances relevant to DOE`s mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials; intelligent processing/manufacturing research; and sustainable environments.

Laboratory Directed Research and Development Program

Energy Technology Data Exchange (ETDEWEB)

Ogeka, G.J.

1991-12-01

Today, new ideas and opportunities, fostering the advancement of technology, are occurring at an ever-increasing rate. It, therefore, seems appropriate that a vehicle be available which fosters the development of these new ideas and technologies, promotes the early exploration and exploitation of creative and innovative concepts, and which develops new fundable'' R D projects and programs. At Brookhaven National Laboratory (BNL), one such method is through its Laboratory Directed Research and Development (LDRD) Program. This discretionary research and development tool is critical in maintaining the scientific excellence and vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor achieving and maintaining staff excellence, and a means to address national needs, with the overall mission of the Department of Energy (DOE) and the Brookhaven National Laboratory. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, they have resulted in numerous publications in various professional and scientific journals, and presentations at meetings and forums.

Ernest Orlando Lawrence Berkeley National Laboratory institutional plan, FY 1996--2001

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-11-01

The FY 1996--2001 Institutional Plan provides an overview of the Ernest Orlando Lawrence Berkeley National Laboratory mission, strategic plan, core business areas, critical success factors, and the resource requirements to fulfill its mission in support of national needs in fundamental science and technology, energy resources, and environmental quality. The Laboratory Strategic Plan section identifies long-range conditions that will influence the Laboratory, as well as potential research trends and management implications. The Core Business Areas section identifies those initiatives that are potential new research programs representing major long-term opportunities for the Laboratory, and the resources required for their implementation. It also summarizes current programs and potential changes in research program activity, science and technology partnerships, and university and science education. The Critical Success Factors section reviews human resources; work force diversity; environment, safety, and health programs; management practices; site and facility needs; and communications and trust. The Resource Projections are estimates of required budgetary authority for the Laboratory`s ongoing research programs. The Institutional Plan is a management report for integration with the Department of Energy`s strategic planning activities, developed through an annual planning process. The plan identifies technical and administrative directions in the context of the national energy policy and research needs and the Department of Energy`s program planning initiatives. Preparation of the plan is coordinated by the Office of Planning and Communications from information contributed by the Laboratory`s scientific and support divisions.

External quality assurance performance of clinical research laboratories in sub-saharan Africa.

Science.gov (United States)

Amukele, Timothy K; Michael, Kurt; Hanes, Mary; Miller, Robert E; Jackson, J Brooks

2012-11-01

Patient Safety Monitoring in International Laboratories (JHU-SMILE) is a resource at Johns Hopkins University that supports and monitors laboratories in National Institutes of Health-funded international clinical trials. To determine the impact of the JHU-SMILE quality assurance scheme in sub-Saharan African laboratories, we reviewed 40 to 60 months of external quality assurance (EQA) results of the College of American Pathologists (CAP) in these laboratories. We reviewed the performance of 8 analytes: albumin, alanine aminotransferase, creatinine, sodium, WBC, hemoglobin, hematocrit, and the human immunodeficiency virus antibody rapid test. Over the 40- to 60-month observation period, the sub-Saharan laboratories had a 1.63% failure rate, which was 40% lower than the 2011 CAP-wide rate of 2.8%. Seventy-six percent of the observed EQA failures occurred in 4 of the 21 laboratories. These results demonstrate that a system of remote monitoring, feedback, and audits can support quality in low-resource settings, even in places without strong regulatory support for laboratory quality.

Idaho National Laboratory Cultural Resource Management Office FY 2010 Activity Report

Energy Technology Data Exchange (ETDEWEB)

Hollie K. Gilbert; Clayton F. Marler; Christina L. Olson; Brenda R. Pace; Julie Braun Williams

2011-09-01

The Idaho National Laboratory (INL) Site is home to vast numbers and a wide variety of important cultural resources representing at least a 13,500 year span of human land use in the region. As a federal agency, the Department of Energy, Idaho Operations Office (DOE-ID) has legal responsibility for the management and protection of the resources and has contracted these responsibilities to Battelle Energy Alliance (BEA). The BEA professional staff is committed to maintaining a cultural resource management program that accepts the challenge of preserving INL cultural resources in a manner reflecting their importance in local, regional, and national history. This report summarizes activities performed by the INL Cultural Resource Management Office (CRMO) staff during fiscal year 2010. This work is diverse, far-reaching and though generally confined to INL cultural resource compliance, also includes a myriad of professional and voluntary community activities. This document is intended to be informative to both internal and external stakeholders and to serve as a planning tool for future INL cultural resource management work.

Lawrence Berkeley Laboratory Institutional Plan, FY 1993--1998

Energy Technology Data Exchange (ETDEWEB)

1992-10-01

The FY 1993--1998 Institutional Plan provides an overview of the Lawrence Berkeley Laboratory mission, strategic plan, scientific initiatives, research programs, environment and safety program plans, educational and technology transfer efforts, human resources, and facilities needs. The Strategic Plan section identifies long-range conditions that can influence the Laboratory, potential research trends, and several management implications. The Initiatives section identifies potential new research programs that represent major long-term opportunities for the Laboratory and the resources required for their implementation. The Scientific and Technical Programs section summarizes current programs and potential changes in research program activity. The Environment, Safety, and Health section describes the management systems and programs underway at the Laboratory to protect the environment, the public, and the employees. The Technology Transfer and Education programs section describes current and planned programs to enhance the nation's scientific literacy and human infrastructure and to improve economic competitiveness. The Human Resources section identifies LBL staff composition and development programs. The section on Site and Facilities discusses resources required to sustain and improve the physical plant and its equipment. The Resource Projections are estimates of required budgetary authority for the Laboratory's ongoing research programs. The plan is an institutional management report for integration with the Department of Energy's strategic planning activities that is developed through an annual planning process. The plan identifies technical and administrative directions in the context of the National Energy Strategy and the Department of Energy's program planning initiatives. Preparation of the plan is coordinated by the Office for Planning and Development from information contributed by the Laboratory's scientific and support divisions.

Research Resources Survey: Radiology Junior Faculty Development.

Science.gov (United States)

Krupinski, Elizabeth A; Votaw, John R

2015-07-01

To assess resources available to junior faculty in US academic radiology departments for research mentorship and funding opportunities and to determine if certain resources are more common in successful programs. An anonymous survey covering scientific environment and research mentorship and was sent to vice-chairs of research of radiology departments. Results were evaluated to identify practices of research programs with respect to mentorship, resources, and opportunities. Academy of Radiology Research's 2012 National Institutes of Health (NIH) grants and awards list was used to determine if environment and practices correlate with funding. There was a 51% response rate. A greater fraction of clinical faculty gets promoted from assistant to associate professor than research faculty. Research faculty overall submits more funding applications. Most programs support start-up costs and K-awards. Over half of the departments have a vice-chair for faculty development, and most have formal mentorship programs. Faculty members are expected to teach, engage in service, publish, and apply for and get research funding within 3 years of hire. Top-tier programs as judged by NIH awards have a combination of MDs who devote >50% effort to research and PhD faculty. Key factors holding back both clinical and research junior faculty development were motivation, resources, and time, although programs reported high availability of resources and support at the department level. Better marketing of resources for junior faculty, effort devoted to mentoring clinical faculty in research, and explicit milestones/expectations for achievement could enhance junior faculty success, promote interest in the clinician–scientist career path for radiologists, and lead to greater research success.

Laboratory Animal Technician | Center for Cancer Research

Science.gov (United States)

PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused

Occupational radiation exposures in research laboratories

International Nuclear Information System (INIS)

Vaccari, S.; Papotti, E.; Pedrazzi, G.

2006-01-01

Radioactive sources are widely used in many research activities at University centers. In particular, the activities concerning use of sealed form ( 57 Co in Moessbauer application) and unsealed form ( 3 H, 14 C, 32 P in radioisotope laboratories) are analyzed. The radiological impact of these materials and potential effective doses to researchers and members of the public were evaluated to show compliance with regulatory limits. A review of the procedures performed by researchers and technicians in the research laboratories with the relative dose evaluations is presented in different situations, including normal operations and emergency situations, for example the fire. A study of the possible exposure to radiation by workers, restricted groups of people, and public in general, as well as environmental releases, is presented. (authors)

Sigurd Lettow - Adapting resources to transform the Laboratory

CERN Multimedia

2009-01-01

As a new physics era begins with the start-up of the LHC, one of the major tasks facing the Director for Administration and General Infrastructure is to transform CERN into a laboratory fit to receive more than 9 000 users. However, limited resources impose difficult trade-offs for a Director who also has to oversee the Laboratory’s finances. Sigurd Lettow is the only Director who has remained in place with the arrival of the new Director-General, Rolf Heuer, and, as Director for Administration and General Infrastructure, he continues to pursue the same priorities he has espoused since his arrival, namely to modernise the Laboratory and prepare it for the LHC’s operational phase. As Sigurd Lettow underlines, "With the new Director General, there is a change in spirit and style, due to his personality and his determination to strengthen communication and adopt an open attitude. However, our priorities are principally connected with...

Genetic composition of laboratory stocks of the self-fertilizing fish Kryptolebias marmoratus: a valuable resource for experimental research.

Directory of Open Access Journals (Sweden)

Andrey Tatarenkov

2010-09-01

Full Text Available The hermaphroditic Mangrove Killifish, Kryptolebias marmoratus, is the world's only vertebrate that routinely self-fertilizes. As such, highly inbred and presumably isogenic "clonal" lineages of this androdioecious species have long been maintained in several laboratories and used in a wide variety of experiments that require genetically uniform vertebrate specimens. Here we conduct a genetic inventory of essentially all laboratory stocks of the Mangrove Killifish held worldwide. At 32 microsatellite loci, these stocks proved to show extensive interline differentiation as well as some intraline variation, much of which can be attributed to post-origin de novo mutations and/or to the segregation of polymorphisms from wild progenitors. Our genetic findings also document that many of the surveyed laboratory strains are not what they have been labeled, apparently due to the rather frequent mishandling or unintended mixing of various laboratory stocks over the years. Our genetic inventory should help to clarify much of this confusion about the clonal identities and genetic relationships of laboratory lines, and thereby help to rejuvenate interest in K. marmoratus as a reliable vertebrate model for experimental research that requires or can capitalize upon "clonal" replicate specimens.

Mouse Genome Informatics (MGI) Resource: Genetic, Genomic, and Biological Knowledgebase for the Laboratory Mouse.

Science.gov (United States)

Eppig, Janan T

2017-07-01

The Mouse Genome Informatics (MGI) Resource supports basic, translational, and computational research by providing high-quality, integrated data on the genetics, genomics, and biology of the laboratory mouse. MGI serves a strategic role for the scientific community in facilitating biomedical, experimental, and computational studies investigating the genetics and processes of diseases and enabling the development and testing of new disease models and therapeutic interventions. This review describes the nexus of the body of growing genetic and biological data and the advances in computer technology in the late 1980s, including the World Wide Web, that together launched the beginnings of MGI. MGI develops and maintains a gold-standard resource that reflects the current state of knowledge, provides semantic and contextual data integration that fosters hypothesis testing, continually develops new and improved tools for searching and analysis, and partners with the scientific community to assure research data needs are met. Here we describe one slice of MGI relating to the development of community-wide large-scale mutagenesis and phenotyping projects and introduce ways to access and use these MGI data. References and links to additional MGI aspects are provided. © The Author 2017. Published by Oxford University Press.

Feasibility of establishing a biosafety level 3 tuberculosis culture laboratory of acceptable quality standards in a resource-limited setting: an experience from Uganda.

Science.gov (United States)

Ssengooba, Willy; Gelderbloem, Sebastian J; Mboowa, Gerald; Wajja, Anne; Namaganda, Carolyn; Musoke, Philippa; Mayanja-Kizza, Harriet; Joloba, Moses Lutaakome

2015-01-15

Despite the recent innovations in tuberculosis (TB) and multi-drug resistant TB (MDR-TB) diagnosis, culture remains vital for difficult-to-diagnose patients, baseline and end-point determination for novel vaccines and drug trials. Herein, we share our experience of establishing a BSL-3 culture facility in Uganda as well as 3-years performance indicators and post-TB vaccine trials (pioneer) and funding experience of sustaining such a facility. Between September 2008 and April 2009, the laboratory was set-up with financial support from external partners. After an initial procedure validation phase in parallel with the National TB Reference Laboratory (NTRL) and legal approvals, the laboratory registered for external quality assessment (EQA) from the NTRL, WHO, National Health Laboratories Services (NHLS), and the College of American Pathologists (CAP). The laboratory also instituted a functional quality management system (QMS). Pioneer funding ended in 2012 and the laboratory remained in self-sustainability mode. The laboratory achieved internationally acceptable standards in both structural and biosafety requirements. Of the 14 patient samples analyzed in the procedural validation phase, agreement for all tests with NTRL was 90% (P 80% in all years from NTRL, CAP, and NHLS, and culture was 100% for CAP panels and above regional average scores for all years with NHLS. Quarterly DST scores from WHO-EQA ranged from 78% to 100% in 2010, 80% to 100% in 2011, and 90 to 100% in 2012. From our experience, it is feasible to set-up a BSL-3 TB culture laboratory with acceptable quality performance standards in resource-limited countries. With the demonstrated quality of work, the laboratory attracted more research groups and post-pioneer funding, which helped to ensure sustainability. The high skilled experts in this research laboratory also continue to provide an excellent resource for the needed national discussion of the laboratory and quality management systems.

Great Lakes Environmental Research Laboratory

Data.gov (United States)

Federal Laboratory Consortium — NOAA-GLERL and its partners conduct innovative research on the dynamic environments and ecosystems of the Great Lakes and coastal regions to provide information for...

Resource management and nonmarket valuation research

Science.gov (United States)

Douglas, A.J.; Taylor, J.G.

1999-01-01

Survey based nonmarket valuation research is often regarded as economics research. However, resource economists need to be aware of and acknowledge the manifold information sources that they employ in order to enhance the policy credibility of their studies. Communication between resource economists and practitioners of allied disciplines including chemistry, civil engineering, sociology, and anthropology are often neglected. Recent resource allocation policy debates have given rise to an extensive discussion of methodological issues that narrow the scope of the subject. The present paper provides a format for the presentation of nonmarket valuation research results that emphasizes the manifold links between economics studies that employ different methodologies to estimate nonmarket resource values. A more robust emphasis on the interlocking features of the different approaches for estimating nonmarket benefits should foster appreciation of the transdisciplinary aspects of the subject.

Water Resources Research Center

Science.gov (United States)

Untitled Document  Search Welcome to the University of Hawai'i at Manoa Water Resources Research Center At WRRC we concentrate on addressing the unique water and wastewater management problems and issues elsewhere by researching water-related issues distinctive to these areas. We are Hawaii's link in a network

Occupational radiation exposures in research laboratories

Energy Technology Data Exchange (ETDEWEB)

Vaccari, S.; Papotti, E. [Parma Univ., Health Physics (Italy); Pedrazzi, G. [Parma Univ., Dept. of Public Health (Italy)

2006-07-01

Radioactive sources are widely used in many research activities at University centers. In particular, the activities concerning use of sealed form ({sup 57}Co in Moessbauer application) and unsealed form ({sup 3}H, {sup 14}C, {sup 32}P in radioisotope laboratories) are analyzed. The radiological impact of these materials and potential effective doses to researchers and members of the public were evaluated to show compliance with regulatory limits. A review of the procedures performed by researchers and technicians in the research laboratories with the relative dose evaluations is presented in different situations, including normal operations and emergency situations, for example the fire. A study of the possible exposure to radiation by workers, restricted groups of people, and public in general, as well as environmental releases, is presented. (authors)

Research System Integration Laboratory (SIL)

Data.gov (United States)

Federal Laboratory Consortium — The VEA Research SIL (VRS) is essential to the success of the TARDEC 30-Year Strategy. The vast majority of the TARDEC Capability Sets face challenging electronics...

Outline of new extra high voltage research equipment at Kumatori research laboratories

Energy Technology Data Exchange (ETDEWEB)

Hohki, S; Ikeda, G

1965-01-01

Following up the construction in 1939 of an ehv research laboratory, another new research laboratory was established at Kumatori with a ground area of 142,000 square meters. As the first stage of this construction plan, the new research equipment was installed in November 1963 and began operation. The laboratory consists of comprehensive ehv research equipment and facilities relating to atomic energy. The former includes a 6000-kV impulse voltage generator, a 1650-kV alternating current testing transformer, a 300-m overhead transmission test line, a tower strength testing facility, and other various high-power test facilities. Studies on a 400- to 500-kV overhead power transmission system and other new transmission systems are currently being conducted. The details of the construction of the ehv research equipment together with the research policy for future ehv engineering are given.

Research resources: curating the new eagle-i discovery system

Science.gov (United States)

Vasilevsky, Nicole; Johnson, Tenille; Corday, Karen; Torniai, Carlo; Brush, Matthew; Segerdell, Erik; Wilson, Melanie; Shaffer, Chris; Robinson, David; Haendel, Melissa

2012-01-01

Development of biocuration processes and guidelines for new data types or projects is a challenging task. Each project finds its way toward defining annotation standards and ensuring data consistency with varying degrees of planning and different tools to support and/or report on consistency. Further, this process may be data type specific even within the context of a single project. This article describes our experiences with eagle-i, a 2-year pilot project to develop a federated network of data repositories in which unpublished, unshared or otherwise ‘invisible’ scientific resources could be inventoried and made accessible to the scientific community. During the course of eagle-i development, the main challenges we experienced related to the difficulty of collecting and curating data while the system and the data model were simultaneously built, and a deficiency and diversity of data management strategies in the laboratories from which the source data was obtained. We discuss our approach to biocuration and the importance of improving information management strategies to the research process, specifically with regard to the inventorying and usage of research resources. Finally, we highlight the commonalities and differences between eagle-i and similar efforts with the hope that our lessons learned will assist other biocuration endeavors. Database URL: www.eagle-i.net PMID:22434835

Idaho National Laboratory Cultural Resource Management Office FY 2011 Activity Report

Energy Technology Data Exchange (ETDEWEB)

Julie Braun Williams; Brenda R. Pace; Hollie K. Gilbert; Christina L. Olson

2012-09-01

The Idaho National Laboratory (INL) Site is home to vast numbers and a wide variety of important cultural resources representing at least a 13,500 year span of human land use in the region. As a federal agency, the Department of Energy, Idaho Operations Office (DOE-ID) has legal responsibility for the management and protection of the resources and has contracted these responsibilities to Battelle Energy Alliance (BEA). The BEA professional staff is committed to maintaining a cultural resource management program that accepts the challenge of preserving INL cultural resources in a manner reflecting their importance in local, regional, and national history. This report is intended as a stand-alone document that summarizes activities performed by the INL Cultural Resource Management Office (CRMO) staff during fiscal year 2011. This work is diverse, far-reaching and though generally confined to INL cultural resource compliance, also includes a myriad of professional and voluntary community activities. This document is intended to be informative to both internal and external stakeholders, serve as a planning tool for future INL cultural resource management work, and meet an agreed upon legal requirement.

NNSA Laboratory Directed Research and Development Program 2008 Symposium--Focus on Energy Security

Energy Technology Data Exchange (ETDEWEB)

Kotta, P R; Sketchley, J A

2008-08-20

The Laboratory Directed Research and Development (LDRD) Program was authorized by Congress in 1991 to fund leading-edge research and development central to the national laboratories core missions. LDRD anticipates and engages in projects on the forefront of science and engineering at the Department of Energy (DOE) national laboratories, and has a long history of addressing pressing national security needs at the National Nuclear Security Administration (NNSA) laboratories. LDRD has been a scientific success story, where projects continue to win national recognition for excellence through prestigious awards, papers published and cited in peer-reviewed journals, mainstream media coverage, and patents granted. The LDRD Program is also a powerful means to attract and retain top researchers from around the world, to foster collaborations with other prominent scientific and technological institutions, and to leverage some of the world's most technologically advanced assets. This enables the LDRD Program to invest in high-risk and potentially high-payoff research that creates innovative technical solutions for some of our nation's most difficult challenges. Worldwide energy demand is growing at an alarming rate, as developing nations continue to expand their industrial and economic base on the back of limited global resources. The resulting international conflicts and environmental consequences pose serious challenges not only to this nation, but to the international community as well. The NNSA and its national security laboratories have been increasingly called upon to devote their scientific and technological capabilities to help address issues that are not limited solely to the historic nuclear weapons core mission, but are more expansive and encompass a spectrum of national security missions, including energy security. This year's symposium highlights some of the exciting areas of research in alternative fuels and technology, nuclear power, carbon

Conservation of resources theory and research use in health systems.

Science.gov (United States)

Alvaro, Celeste; Lyons, Renée F; Warner, Grace; Hobfoll, Stevan E; Martens, Patricia J; Labonté, Ronald; Brown, Richard E

2010-10-20

Health systems face challenges in using research evidence to improve policy and practice. These challenges are particularly evident in small and poorly resourced health systems, which are often in locations (in Canada and globally) with poorer health status. Although organizational resources have been acknowledged as important in understanding research use resource theories have not been a focus of knowledge translation (KT) research. What resources, broadly defined, are required for KT and how does their presence or absence influence research use?In this paper, we consider conservation of resources (COR) theory as a theoretical basis for understanding the capacity to use research evidence in health systems. Three components of COR theory are examined in the context of KT. First, resources are required for research uptake. Second, threat of resource loss fosters resistance to research use. Third, resources can be optimized, even in resource-challenged environments, to build capacity for KT. A scan of the KT literature examined organizational resources needed for research use. A multiple case study approach examined the three components of COR theory outlined above. The multiple case study consisted of a document review and key informant interviews with research team members, including government decision-makers and health practitioners through a retrospective analysis of four previously conducted applied health research studies in a resource-challenged region. The literature scan identified organizational resources that influence research use. The multiple case study supported these findings, contributed to the development of a taxonomy of organizational resources, and revealed how fears concerning resource loss can affect research use. Some resources were found to compensate for other resource deficits. Resource needs differed at various stages in the research use process. COR theory contributes to understanding the role of resources in research use, resistance to

Biomedical laboratory science education: standardising teaching content in resource-limited countries

Directory of Open Access Journals (Sweden)

Wendy Arneson

2013-06-01

Full Text Available Background: There is a worldwide shortage of qualified laboratory personnel to provide adequate testing for the detection and monitoring of diseases. In an effort to increase laboratory capacity in developing countries, new skills have been introduced into laboratory services. Curriculum revision with a focus on good laboratory practice is an important aspect of supplying entry-level graduates with the competencies needed to meet the current needs. Objectives: Gaps in application and problem-solving competencies of newly graduated laboratory personnel were discovered in Ethiopia, Tanzania and Kenya. New medical laboratory teaching content was developed in Ethiopia, Tanzania and Kenya using national instructors, tutors, and experts and consulting medical laboratory educators from the United States of America (USA. Method: Workshops were held in Ethiopia to create standardised biomedical laboratory science (BMLS lessons based on recently-revised course objectives with an emphasis on application of skills. In Tanzania, course-module teaching guides with objectives were developed based on established competency outcomes and tasks. In Kenya, example interactive presentations and lesson plans were developed by the USA medical laboratory educators prior to the workshop to serve as resources and templates for the development of lessons within the country itself. Results: The new teaching materials were implemented and faculty, students and other stakeholders reported successful outcomes. Conclusions: These approaches to updating curricula may be helpful as biomedical laboratory schools in other countries address gaps in the competencies of entry-level graduates.

78 FR 28292 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Science.gov (United States)

2013-05-14

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board; Notice of Meetings; Amendment The... Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development...

Laboratory Directed Research and Development FY-15 Annual Report

Energy Technology Data Exchange (ETDEWEB)

Pillai, Rekha Sukamar [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2016-03-01

The Laboratory Directed Research and Development (LDRD) Program at Idaho National Laboratory (INL) reports its status to the U.S. Department of Energy (DOE) by March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the laboratory director broad flexibility for program implementation. LDRD funds are obtained through a charge to all INL programs. This report includes summaries of all INL LDRD research activities supported during Fiscal Year (FY) 2015.

Laboratory Directed Research and Development FY-10 Annual Report

Energy Technology Data Exchange (ETDEWEB)

Dena Tomchak

2011-03-01

The FY 2010 Laboratory Directed Research and Development (LDRD) Annual Report is a compendium of the diverse research performed to develop and ensure the INL's technical capabilities can support the future DOE missions and national research priorities. LDRD is essential to the INL -- it provides a means for the laboratory to pursue novel scientific and engineering research in areas that are deemed too basic or risky for programmatic investments. This research enhances technical capabilities at the laboratory, providing scientific and engineering staff with opportunities for skill building and partnership development.

Laboratory Directed Research and Development Program FY 2008 Annual Report

Energy Technology Data Exchange (ETDEWEB)

editor, Todd C Hansen

2009-02-23

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2008 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD program supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under

Laboratory Directed Research and Development Program FY 2008 Annual Report

International Nuclear Information System (INIS)

Hansen, Todd C.

2009-01-01

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Themes that are codified in DOE's 2006 Strategic Plan (DOE/CF-0010), with a primary focus on Scientific Discovery and Innovation. For that strategic theme, the Fiscal Year (FY) 2008 LDRD projects support each one of the three goals through multiple strategies described in the plan. In addition, LDRD efforts support the four goals of Energy Security, the two goals of Environmental Responsibility, and Nuclear Security (unclassified fundamental research that supports stockpile safety and nonproliferation programs). The LDRD program supports Office of Science strategic plans, including the 20-year Scientific Facilities Plan and the Office of Science Strategic Plan. The research also supports the strategic directions periodically under consideration and review by the

Department of Energy multiprogram laboratories

International Nuclear Information System (INIS)

1982-09-01

The Panel recommends the following major roles and missions for the laboratories: perform the Department's national trust fundamental research missions in the physical sciences, including high energy and nuclear physics, and the radiobiological sciences including nuclear medicine; sustain scientific staff core capabilities and specialized research facilities for laboratory research purposes and for use by other Federal agencies and the private sector; perform independent scientific and technical assessment or verification studies required by the Department; and perform generic research and development where it is judged to be in the public interest or where for economic or technical reasons industry does not choose to support it. Organizational efficiencies if implemented by the Department could contribute toward optimal performance of the laboratories. The Panel recommends that a high level official, such as a Deputy Under Secretary, be appointed to serve as Chief Laboratory Executive with authority to help determine and defend the research and development budget, to allocate resources, to decide where work is to be done, and to assess periodically laboratory performance. Laboratory directors should be given substantially more flexibility to deploy resources and to initiate or adapt programs within broad guidelines provided by the Department. The panel recommends the following actions to increase the usefulness of the laboratories and to promote technology transfer to the private sector: establish user groups for all major mission programs and facilities to ensure greater relevance for Department and laboratory efforts; allow the laboratories to do more reimbursable work for others (other Federal agencies, state and local governments, and industry) by relaxing constraints on such work; implement vigorously the recently liberalized patent policy; permit and encourage joint ventures with industry

Ernest Orlando Berkeley National Laboratory - Fundamental and applied research on lean premixed combustion

International Nuclear Information System (INIS)

Cheng, Robert K.

1999-01-01

Ernest Orland Lawrence Berkeley National Laboratory (Berkeley Lab) is the oldest of America's national laboratories and has been a leader in science and engineering technology for more than 65 years, serving as a powerful resource to meet Us national needs. As a multi-program Department of Energy laboratory, Berkeley Lab is dedicated to performing leading edge research in the biological, physical, materials, chemical, energy, environmental and computing sciences. Ernest Orlando Lawrence, the Lab's founder and the first of its nine Nobel prize winners, invented the cyclotron, which led to a Golden Age of particle physics and revolutionary discoveries about the nature of the universe. To this day, the Lab remains a world center for accelerator and detector innovation and design. The Lab is the birthplace of nuclear medicine and the cradle of invention for medical imaging. In the field of heart disease, Lab researchers were the first to isolate lipoproteins and the first to determine that the ratio of high density to low density lipoproteins is a strong indicator of heart disease risk. The demise of the dinosaurs--the revelation that they had been killed off by a massive comet or asteroid that had slammed into the Earth--was a theory developed here. The invention of the chemical laser, the unlocking of the secrets of photosynthesis--this is a short preview of the legacy of this Laboratory

Conservation of resources theory and research use in health systems

Directory of Open Access Journals (Sweden)

Hobfoll Stevan E

2010-10-01

Full Text Available Abstract Background Health systems face challenges in using research evidence to improve policy and practice. These challenges are particularly evident in small and poorly resourced health systems, which are often in locations (in Canada and globally with poorer health status. Although organizational resources have been acknowledged as important in understanding research use resource theories have not been a focus of knowledge translation (KT research. What resources, broadly defined, are required for KT and how does their presence or absence influence research use? In this paper, we consider conservation of resources (COR theory as a theoretical basis for understanding the capacity to use research evidence in health systems. Three components of COR theory are examined in the context of KT. First, resources are required for research uptake. Second, threat of resource loss fosters resistance to research use. Third, resources can be optimized, even in resource-challenged environments, to build capacity for KT. Methods A scan of the KT literature examined organizational resources needed for research use. A multiple case study approach examined the three components of COR theory outlined above. The multiple case study consisted of a document review and key informant interviews with research team members, including government decision-makers and health practitioners through a retrospective analysis of four previously conducted applied health research studies in a resource-challenged region. Results The literature scan identified organizational resources that influence research use. The multiple case study supported these findings, contributed to the development of a taxonomy of organizational resources, and revealed how fears concerning resource loss can affect research use. Some resources were found to compensate for other resource deficits. Resource needs differed at various stages in the research use process. Conclusions COR theory contributes to

Research laboratories annual report 1991

International Nuclear Information System (INIS)

1992-08-01

The 1990-1991 activities, of the Israel Atomic Energy Commission's research laboratories, are presented in this report. The main fields of interest are chemistry and material sciences, life and environmental sciences, nuclear physics and technology

78 FR 66992 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Science.gov (United States)

2013-11-07

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical... the panels of the Joint Biomedical Laboratory Research and Development and Clinical Science Research..., behavioral, and clinical science research. The panel meetings will be open to the public for approximately...

75 FR 57833 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Science.gov (United States)

2010-09-22

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical... the panels of the Joint Biomedical Laboratory Research and Development and Clinical Science Research... Crowne Plaza Clinical Research Program December 3, 2010 *VA Central Office Mental Hlth & Behav Sci-A...

78 FR 22622 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Science.gov (United States)

2013-04-16

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical... the panels of the Joint Biomedical Laboratory Research and Development and Clinical Science Research... biomedical, behavioral and clinical science research. The panel meetings will be open to the public for...

Laboratory Directed Research and Development Annual Report FY 2017

Energy Technology Data Exchange (ETDEWEB)

Sullivan, Kelly O.

2018-03-30

A national laboratory must establish and maintain an environment in which creativity and innovation are encouraged and supported in order to fulfill its missions and remain viable in the long term. As such, multiprogram laboratories are given discretion to allocate a percentage of their operating budgets to support research and development projects that align to PNNL’s and DOE’s missions and support the missions of other federal agencies, including DHS, DOD, and others. DOE Order 413.2C sets forth DOE’s Laboratory Directed Research and Development (LDRD) policy and guidelines for DOE multiprogram laboratories, and it authorizes the national laboratories to allocate up to 6 percent of their operating budgets to fund the program. LDRD is innovative research and development, selected by the Laboratory Director or his/her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory. The projects supported by LDRD funding all have demonstrable ties to DOE/DHS missions and may also be relevant to the missions of other federal agencies that sponsor work at the Laboratory. The program plays a key role in attracting the best and brightest scientific staff, which is needed to serve the highest priority DOE mission objectives. Individual project reports comprise the bulk of this LDRD report. The Laboratory focuses its LDRD research on scientific assets that often address more than one scientific discipline.

Laboratory Directed Research and Development Annual Report FY 2016

Energy Technology Data Exchange (ETDEWEB)

Sullivan, Kelly O. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2017-03-30

A national laboratory must establish and maintain an environment in which creativity and innovation are encouraged and supported in order to fulfill its missions and remain viable in the long term. As such, multiprogram laboratories are given discretion to allocate a percentage of their operating budgets to support research and development projects that align to PNNL’s and DOE’s missions and support the missions of other federal agencies, including DHS, DOD, and others. DOE Order 413.2C sets forth DOE’s Laboratory Directed Research and Development (LDRD) policy and guidelines for DOE multiprogram laboratories, and it authorizes the national laboratories to allocate up to 6 percent of their operating budgets to fund the program. LDRD is innovative research and development, selected by the Laboratory Director or his/her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory. The projects supported by LDRD funding all have demonstrable ties to DOE/DHS missions and may also be relevant to the missions of other federal agencies that sponsor work at the Laboratory. The program plays a key role in attracting the best and brightest scientific staff, which is needed to serve the highest priority DOE mission objectives. Individual project reports comprise the bulk of this LDRD report. The Laboratory focuses its LDRD research on scientific assets that often address more than one scientific discipline.

The Biomedical Resource Ontology (BRO) to enable resource discovery in clinical and translational research.

Science.gov (United States)

Tenenbaum, Jessica D; Whetzel, Patricia L; Anderson, Kent; Borromeo, Charles D; Dinov, Ivo D; Gabriel, Davera; Kirschner, Beth; Mirel, Barbara; Morris, Tim; Noy, Natasha; Nyulas, Csongor; Rubenson, David; Saxman, Paul R; Singh, Harpreet; Whelan, Nancy; Wright, Zach; Athey, Brian D; Becich, Michael J; Ginsburg, Geoffrey S; Musen, Mark A; Smith, Kevin A; Tarantal, Alice F; Rubin, Daniel L; Lyster, Peter

2011-02-01

The biomedical research community relies on a diverse set of resources, both within their own institutions and at other research centers. In addition, an increasing number of shared electronic resources have been developed. Without effective means to locate and query these resources, it is challenging, if not impossible, for investigators to be aware of the myriad resources available, or to effectively perform resource discovery when the need arises. In this paper, we describe the development and use of the Biomedical Resource Ontology (BRO) to enable semantic annotation and discovery of biomedical resources. We also describe the Resource Discovery System (RDS) which is a federated, inter-institutional pilot project that uses the BRO to facilitate resource discovery on the Internet. Through the RDS framework and its associated Biositemaps infrastructure, the BRO facilitates semantic search and discovery of biomedical resources, breaking down barriers and streamlining scientific research that will improve human health. Copyright © 2010 Elsevier Inc. All rights reserved.

76 FR 19188 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Science.gov (United States)

2011-04-06

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical... the panels of the Joint Biomedical Laboratory Research and Development and Clinical Science Research.... Neurobiology-D June 10, 2011 Crowne Plaza DC/Silver Spring. Clinical Research Program June 13, 2011 VA Central...

75 FR 23847 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Science.gov (United States)

2010-05-04

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical... panels of the Joint Biomedical Laboratory Research and Development and Clinical Science Research and... & Behav Sci-A June 7, 2010 L'Enfant Plaza Hotel. Clinical Research Program June 9, 2010 *VA Central Office...

Research and Progress on Virtual Cloud Laboratory

Directory of Open Access Journals (Sweden)

Zhang Jian Wei

2016-01-01

Full Text Available In recent years, cloud computing technology has experienced continuous development and improvement, and has gradually expanded to the education sector. First, this paper will introduce the background knowledge of the current virtual cloud laboratory; by comparing the advantages and disadvantages between traditional laboratory and virtual cloud laboratory, and comparing the application, advantages and disadvantages, and development trend of OpenStack technology and VMWare technology in safety, performance, design, function, use case, and value of virtual cloud laboratory, this paper concludes that application based on OpenStack virtual cloud laboratory in universities and research institutes and other departments is essential.

1995 Laboratory-Directed Research and Development Annual report

International Nuclear Information System (INIS)

Cauffman, D.P.; Shoaf, D.L.; Hill, D.A.; Denison, A.B.

1995-01-01

The Laboratory-Directed Research and Development Program (LDRD) is a key component of the discretionary research conducted by Lockheed Idaho Technologies Company (Lockheed Idaho) at the Idaho National Engineering Laboratory (INEL). The threefold purpose and goal of the LDRD program is to maintain the scientific and technical vitality of the INEL, respond to and support new technical opportunities, and enhance the agility and flexibility of the national laboratory and Lockheed Idaho to address the current and future missions of the Department of Energy

1995 Laboratory-Directed Research and Development Annual report

Energy Technology Data Exchange (ETDEWEB)

Cauffman, D.P.; Shoaf, D.L.; Hill, D.A.; Denison, A.B.

1995-12-31

The Laboratory-Directed Research and Development Program (LDRD) is a key component of the discretionary research conducted by Lockheed Idaho Technologies Company (Lockheed Idaho) at the Idaho National Engineering Laboratory (INEL). The threefold purpose and goal of the LDRD program is to maintain the scientific and technical vitality of the INEL, respond to and support new technical opportunities, and enhance the agility and flexibility of the national laboratory and Lockheed Idaho to address the current and future missions of the Department of Energy.

Operational Changes in a Shared Resource Laboratory with the Use of a Product Lifecycle Management Approach: A Case Study.

Science.gov (United States)

Hexley, Philip; Smith, Victoria; Wall, Samantha

2016-04-01

Shared Resource Laboratories (SRLs) provide investigators access to necessary scientific and resource expertise to leverage complex technologies fully for advancing high-quality biomedical research in a cost-effective manner. At the University of Nebraska Medical Center, the Flow Cytometry Research Facility (FCRF) offered access to exceptional technology, but the methods of operation were outdated and unsustainable. Whereas technology has advanced and the institute has expanded, the operations at the facility remained unchanged for 35 yr. To rectify this, at the end of 2013, we took a product lifecycle management approach to affect large operational changes and align the services offered with the SRL goal of education, as well as to provide service to researchers. These disruptive operational changes took over 10 mo to complete and allowed for independent end-user acquisition of flow cytometry data. The results have been monitored for the past 12 mo. The operational changes have had a positive impact on the quality of research, increased investigator-facility interaction, reduced stress of facility staff, and increased overall use of the resources. This product lifecycle management approach to facility operations allowed us to conceive of, design, implement, and monitor effectively the changes at the FCRF. This approach should be considered by SRL management when faced with the need for operationally disruptive measures.

Safe handling of plutonium in research laboratories

International Nuclear Information System (INIS)

1976-01-01

The training film illustrates the main basic requirements for the safe handling of small amounts of plutonium. The film is intended not only for people setting up plutonium research laboratories but also for all those who work in existing plutonium research laboratories. It was awarded the first prize in the category ''Protection of Workers'' at the international film festival organized by the 4th World Congress of the International Radiation Protection Association (IRPA) in Paris in April 1977

Safe handling of plutonium in research laboratories

Energy Technology Data Exchange (ETDEWEB)

NONE

1977-12-31

The training film illustrates the main basic requirements for the safe handling of small amounts of plutonium. The film is intended not only for people setting up plutonium research laboratories but also for all those who work in existing plutonium research laboratories. It was awarded the first prize in the category ``Protection of Workers`` at the international film festival organized by the 4th World Congress of the International Radiation Protection Association (IRPA) in Paris in April 1977

Virtual laboratory for fusion research in Japan

International Nuclear Information System (INIS)

Tsuda, K.; Nagayama, Y.; Yamamoto, T.; Horiuchi, R.; Ishiguro, S.; Takami, S.

2008-01-01

A virtual laboratory system for nuclear fusion research in Japan has been developed using SuperSINET, which is a super high-speed network operated by National Institute of Informatics. Sixteen sites including major Japanese universities, Japan Atomic Energy Agency and National Institute for Fusion Science (NIFS) are mutually connected to SuperSINET with the speed of 1 Gbps by the end of 2006 fiscal year. Collaboration categories in this virtual laboratory are as follows: the large helical device (LHD) remote participation; the remote use of supercomputer system; and the all Japan ST (Spherical Tokamak) research program. This virtual laboratory is a closed network system, and is connected to the Internet through the NIFS firewall in order to keep higher security. Collaborators in a remote station can control their diagnostic devices at LHD and analyze the LHD data as they were at the LHD control room. Researchers in a remote station can use the supercomputer of NIFS in the same environment as NIFS. In this paper, we will describe detail of technologies and the present status of the virtual laboratory. Furthermore, the items that should be developed in the near future are also described

Open- and Closed-Formula Laboratory Animal Diets and Their Importance to Research

OpenAIRE

Barnard, Dennis E; Lewis, Sherry M; Teter, Beverly B; Thigpen, Julius E

2009-01-01

Almost 40 y ago the scientific community was taking actions to control environmental factors that contribute to variation in the responses of laboratory animals to scientific manipulation. Laboratory animal diet was recognized as an important variable. During the 1970s, the American Institute of Nutrition, National Academy of Science, Institute of Laboratory Animal Resources, and Laboratory Animals Centre Diets Advisory Committee supported the use of ‘standard reference diets’ in biomedical r...

77 FR 64598 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Science.gov (United States)

2012-10-22

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical...) that the panels of the Joint Biomedical Laboratory Research and Development and Clinical Science... areas of biomedical, behavioral and clinical science research. The panel meetings will be open to the...

Senior Laboratory Animal Technician | Center for Cancer Research

Science.gov (United States)

PROGRAM DESCRIPTION The Laboratory Animal Sciences Program (LASP) provides exceptional quality animal care and technical support services for animal research performed at the National Cancer Institute at the Frederick National Laboratory for Cancer Research. LASP executes this mission by providing a broad spectrum of state-of-the-art technologies and services that are focused

Communities, Livelihoods and Natural Resources : Action Research ...

International Development Research Centre (IDRC) Digital Library (Canada)

Communities, Livelihoods and Natural Resources : Action Research and Policy Change in Asia. Couverture du livre Communities, Livelihoods and Natural Resources: Action Research and Policy Change in. Directeur(s) : Stephen R. Tyler. Maison(s) d'édition : Practical Action Publishing, CRDI. 1 janvier 2006. ISBN :.

Other Resources for Researchers

African Journals Online (AJOL)

The AfricaPortal is an online resource of policy research on African issues. ... Over 3000 Open Access books, journals and digital documents relating to African ... guides. http://www.lib.monash.edu.au/tutorials/citing/harvard.html Harvard Style.

Water resources management in Tanzania: identifying research ...

African Journals Online (AJOL)

This paper aims at identifying research gaps and needs and recommendations for a research agenda on water resources management in Tanzania. We reviewed published literature on water resources management in Tanzania in order to highlight what is currently known, and to identify knowledge gaps, and suggest ...

Progress report for (1974-1984) of Nuclear Research Laboratory, Srinagar, Kashmir

International Nuclear Information System (INIS)

Kaul, P.K.; Razdan, H.

1985-01-01

The Nuclear Research Laboratory, established at Srinagar in 1974, serves as a base laboratory to organise research activities at the High Altitude Research Laboratory at Gulmarg. Space physics, nuclear physics, radiation and atmospheric chemistry, and technical physics: are the fields in which the research facilities are established at the Laboratory, over the past ten years. The highlights of the various research programmes undertaken at the Laboratory during the period 1974-1984 are presented in the form of summaries. A list of papers published in various journals and presented at different conferences, symposia etc. is given at the end. (M.G.B.)

1999 LDRD Laboratory Directed Research and Development

Energy Technology Data Exchange (ETDEWEB)

Rita Spencer; Kyle Wheeler

2000-06-01

This is the FY 1999 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5) engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.

Laboratory directed research and development

Energy Technology Data Exchange (ETDEWEB)

1991-11-15

The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory's R D capabilities, and further the development of its strategic initiatives. Among the aims of the projects supported by the Program are establishment of engineering proof-of-principle''; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these project are closely associated with major strategic thrusts of the Laboratory as described in Argonne's Five Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne. Areas of emphasis are (1) advanced accelerator and detector technology, (2) x-ray techniques in biological and physical sciences, (3) advanced reactor technology, (4) materials science, computational science, biological sciences and environmental sciences. Individual reports summarizing the purpose, approach, and results of projects are presented.

Powder X-ray diffraction laboratory, Reston, Virginia

Science.gov (United States)

Piatak, Nadine M.; Dulong, Frank T.; Jackson, John C.; Folger, Helen W.

2014-01-01

The powder x-ray diffraction (XRD) laboratory is managed jointly by the Eastern Mineral and Environmental Resources and Eastern Energy Resources Science Centers. Laboratory scientists collaborate on a wide variety of research problems involving other U.S. Geological Survey (USGS) science centers and government agencies, universities, and industry. Capabilities include identification and quantification of crystalline and amorphous phases, and crystallographic and atomic structure analysis for a wide variety of sample media. Customized laboratory procedures and analyses commonly are used to characterize non-routine samples including, but not limited to, organic and inorganic components in petroleum source rocks, ore and mine waste, clay minerals, and glassy phases. Procedures can be adapted to meet a variety of research objectives.

Activities as a research resource

Directory of Open Access Journals (Sweden)

Carla Regina Silva

2013-12-01

Full Text Available Activities play a guiding central role in occupational therapy, articulating to its utilization, the understanding and assessment of its capabilities in numerous and different interventions arising from this field. In this study, we aim to present the use of activities as a research methodology resource. Considering the pathways studied in a master’s research followed by a PhD work, some applications of this resource are reported as a powerful strategy of investigation for the occupational therapy researcher. It is about structuring, systematizing, and analyzing the activities proposed in professional practice by the theoretical and methodological rigor used in the research works. It emphasizes how the use of these activities can be considered important data, records, instruments and sources for different research methods, especially for qualitative analyses. Workshop activities were offered in the above mentioned studies; they were used as communication instruments and expressions of personal and collective experiences, supplying data to understand the actions of subjects and collectives. Furthermore, this strategy was applied as spaces of experimentation, learning and expression, where each participant was conceived as an active being of the process, in a way that the proposal could result in democratic experiences that reflected greater interest and participation, and a more complex presentation of the research data. It is worth mentioning that other methodological procedures, which substantiated the analyses and interpretation of the data collected, were also used. It was possible to conclude that activities, mainly as a qualitative research resource, constituted materialities in different languages and expressions that enriched the analyses arising from micro-realities, producing a repertoire of information that supported the interpretations required for the investigative processes.

Current safety practices in nano-research laboratories in China.

Science.gov (United States)

Zhang, Can; Zhang, Jing; Wang, Guoyu

2014-06-01

China has become a key player in the global nanotechnology field, however, no surveys have specifically examined safety practices in the Chinese nano-laboratories in depth. This study reports results of a survey of 300 professionals who work in research laboratories that handle nanomaterials in China. We recruited participants at three major nano-research laboratories (which carry out research in diverse fields such as chemistry, material science, and biology) and the nano-chemistry session of the national meeting of the Chinese Chemical Society. Results show that almost all nano-research laboratories surveyed had general safety regulations, whereas less than one third of respondents reported having nanospecific safety rules. General safety measures were in place in most surveyed nano-research laboratories, while nanospecific protective measures existed or were implemented less frequently. Several factors reported from the scientific literature including nanotoxicology knowledge gaps, technical limitations on estimating nano-exposure, and the lack of nano-occupational safety legislation may contribute to the current state of affairs. With these factors in mind and embracing the precautionary principle, we suggest strengthening or providing nanosafety training (including raising risk awareness) and establishing nanosafety guidelines in China, to better protect personnel in the nano-workplace.

Laboratory technology research: Abstracts of FY 1998 projects

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-11-01

The Laboratory Technology Research (LTR) program supports high-risk, multidisciplinary research partnerships to investigate challenging scientific problems whose solutions have promising commercial potential. These partnerships capitalize on two great strengths of the country: the world-class basic research capability of the DOE Office of Science (SC) national laboratories and the unparalleled entrepreneurial spirit of American industry. Projects supported by the LTR program in FY 1998 explore the applications of basic research advances relevant to DOE`s mission over a full range of scientific disciplines. The program presently emphasizes three critical areas of mission-related research: advanced materials, intelligent processing and manufacturing research, and environmental and biomedical research. Abstracts for 85 projects are contained in this report.

Brookhaven National Laboratory Institutional Plan FY2001--FY2005

Energy Technology Data Exchange (ETDEWEB)

Davis, S.

2000-10-01

Brookhaven National Laboratory is a multidisciplinary laboratory in the Department of Energy National Laboratory system and plays a lead role in the DOE Science and Technology mission. The Laboratory also contributes to the DOE missions in Energy Resources, Environmental Quality, and National Security. Brookhaven strives for excellence in its science research and in facility operations and manages its activities with particular sensitivity to environmental and community issues. The Laboratory's programs are aligned continuously with the goals and objectives of the DOE through an Integrated Planning Process. This Institutional Plan summarizes the portfolio of research and capabilities that will assure success in the Laboratory's mission in the future. It also sets forth BNL strategies for our programs and for management of the Laboratory. The Department of Energy national laboratory system provides extensive capabilities in both world class research expertise and unique facilities that cannot exist without federal support. Through these national resources, which are available to researchers from industry, universities, other government agencies and other nations, the Department advances the energy, environmental, economic and national security well being of the US, provides for the international advancement of science, and educates future scientists and engineers.

The gene trap resource: a treasure trove for hemopoiesis research.

Science.gov (United States)

Forrai, Ariel; Robb, Lorraine

2005-08-01

The laboratory mouse is an invaluable tool for functional gene discovery because of its genetic malleability and a biological similarity to human systems that facilitates identification of human models of disease. A number of mutagenic technologies are being used to elucidate gene function in the mouse. Gene trapping is an insertional mutagenesis strategy that is being undertaken by multiple research groups, both academic and private, in an effort to introduce mutations across the mouse genome. Large-scale, publicly funded gene trap programs have been initiated in several countries with the International Gene Trap Consortium coordinating certain efforts and resources. We outline the methodology of mammalian gene trapping and how it can be used to identify genes expressed in both primitive and definitive blood cells and to discover hemopoietic regulator genes. Mouse mutants with hematopoietic phenotypes derived using gene trapping are described. The efforts of the large-scale gene trapping consortia have now led to the availability of libraries of mutagenized ES cell clones. The identity of the trapped locus in each of these clones can be identified by sequence-based searching via the world wide web. This resource provides an extraordinary tool for all researchers wishing to use mouse genetics to understand gene function.

Research resources for Drosophila: the expanding universe.

Science.gov (United States)

Matthews, Kathleen A; Kaufman, Thomas C; Gelbart, William M

2005-03-01

Drosophila melanogaster has been the subject of research into central questions about biological mechanisms for almost a century. The experimental tools and resources that are available or under development for D. melanogaster and its related species, particularly those for genomic analysis, are truly outstanding. Here we review three types of resource that have been developed for D. melanogaster research: databases and other sources of information, biological materials and experimental services. These resources are there to be exploited and we hope that this guide will encourage new uses for D. melanogaster information, materials and services, both by those new to flies and by experienced D. melanogaster researchers.

Biological and Physical Space Research Laboratory 2002 Science Review

Science.gov (United States)

Curreri, P. A. (Editor); Robinson, M. B. (Editor); Murphy, K. L. (Editor)

2003-01-01

With the International Space Station Program approaching core complete, our NASA Headquarters sponsor, the new Code U Enterprise, Biological and Physical Research, is shifting its research emphasis from purely fundamental microgravity and biological sciences to strategic research aimed at enabling human missions beyond Earth orbit. Although we anticipate supporting microgravity research on the ISS for some time to come, our laboratory has been vigorously engaged in developing these new strategic research areas.This Technical Memorandum documents the internal science research at our laboratory as presented in a review to Dr. Ann Whitaker, MSFC Science Director, in July 2002. These presentations have been revised and updated as appropriate for this report. It provides a snapshot of the internal science capability of our laboratory as an aid to other NASA organizations and the external scientific community.

Informatics solutions for bridging the gap between clinical and laboratory services in a low-resource setting

Directory of Open Access Journals (Sweden)

Julia Driessen

2015-06-01

Full Text Available Background: There has been little formal analysis of laboratory systems in resource-limited settings, despite widespread consensus around the importance of a strong laboratory infrastructure. Objectives: This study details the informational challenges faced by the laboratory at Kamuzu Central Hospital, a tertiary health facility in Malawi; and proposes ways in which informatics can bolster the efficiency and role of low-resource laboratory systems. Methods: We evaluated previously-collected data on three different aspects of laboratory use. A four-week quality audit of laboratory test orders quantified challenges associated with collecting viable specimens for testing. Data on tests run by the laboratory over a one yearperiod described the magnitude of the demand for laboratory services. Descriptive information about the laboratory workflow identified informational process breakdowns in the pre-analytical and post-analytical phases and was paired with a 24-hour sample of laboratory data on results reporting. Results: The laboratory conducted 242 242 tests over a 12-month period. The four-week quality audit identified 54% of samples as untestable. Prohibitive paperwork errors were identified in 16% of samples. Laboratory service workflows indicated a potential process breakdown in sample transport and results reporting resulting from the lack of assignment of these tasks to any specific employee cadre. The study of result reporting time showed a mean of almost six hours, with significant variation. Conclusions: This analysis identified challenges in each phase of laboratory testing. Informatics could improve the management of this information by streamlining test ordering and the communication of test orders to the laboratory and results back to the ordering physician.

Cyber Defense Research and Monitoring Laboratory

Data.gov (United States)

Federal Laboratory Consortium — This facility acts as a fusion point for bridging ARL's research in tactical and operational Information Assurance (IA) areas and the development and assessment of...

GaInSn usage in the research laboratory

International Nuclear Information System (INIS)

Morley, N. B.; Burris, J.; Cadwallader, L. C.; Nornberg, M. D.

2008-01-01

GaInSn, a eutectic alloy, has been successfully used in the Magneto-Thermofluid Research Laboratory at the University of California-Los Angeles and at the Princeton Plasma Physics Laboratory for the past six years. This paper describes the handling and safety of GaInSn based on the experience gained in these institutions, augmented by observations from other researchers in the liquid metal experimental community. GaInSn is an alloy with benign properties and shows considerable potential in liquid metal experimental research and cooling applications

The Johns Hopkins Hunterian Laboratory Philosophy: Mentoring Students in a Scientific Neurosurgical Research Laboratory.

Science.gov (United States)

Tyler, Betty M; Liu, Ann; Sankey, Eric W; Mangraviti, Antonella; Barone, Michael A; Brem, Henry

2016-06-01

After over 50 years of scientific contribution under the leadership of Harvey Cushing and later Walter Dandy, the Johns Hopkins Hunterian Laboratory entered a period of dormancy between the 1960s and early 1980s. In 1984, Henry Brem reinstituted the Hunterian Neurosurgical Laboratory, with a new focus on localized delivery of therapies for brain tumors, leading to several discoveries such as new antiangiogenic agents and Gliadel chemotherapy wafers for the treatment of malignant gliomas. Since that time, it has been the training ground for 310 trainees who have dedicated their time to scientific exploration in the lab, resulting in numerous discoveries in the area of neurosurgical research. The Hunterian Neurosurgical Laboratory has been a unique example of successful mentoring in a translational research environment. The laboratory's philosophy emphasizes mentorship, independence, self-directed learning, creativity, and people-centered collaboration, while maintaining productivity with a focus on improving clinical outcomes. This focus has been served by the diverse backgrounds of its trainees, both in regard to educational status as well as culturally. Through this philosophy and strong legacy of scientific contribution, the Hunterian Laboratory has maintained a positive and productive research environment that supports highly motivated students and trainees. In this article, the authors discuss the laboratory's training philosophy, linked to the principles of adult learning (andragogy), as well as the successes and the limitations of including a wide educational range of students in a neurosurgical translational laboratory and the phenomenon of combining clinical expertise with rigorous scientific training.

National Renewable Energy Laboratory Information Resources Catalog 2002

Energy Technology Data Exchange (ETDEWEB)

2003-01-01

NREL's ninth annual Information Resources Catalog can keep you up-to-date on the research, development, opportunities, and available technologies in energy efficiency and renewable energy. It includes five main sections with entries grouped according to subject area.

Otolaryngology Residency Program Research Resources and Scholarly Productivity.

Science.gov (United States)

Villwock, Jennifer A; Hamill, Chelsea S; Nicholas, Brian D; Ryan, Jesse T

2017-06-01

Objective To delineate research resources available to otolaryngology residents and their impact on scholarly productivity. Study Design Survey of current otolaryngology program directors. Setting Otolaryngology residency programs. Subjects and Methods An anonymous web-based survey was sent to 98 allopathic otolaryngology training program directors. Fisher exact tests and nonparametric correlations were used to determine statistically significant differences among various strata of programs. Results Thirty-nine percent (n = 38) of queried programs responded. Fourteen (37%) programs had 11 to 15 full-time, academic faculty associated with the residency program. Twenty (53%) programs have a dedicated research coordinator. Basic science lab space and financial resources for statistical work were present at 22 programs (58%). Funding is uniformly provided for presentation of research at conferences; a minority of programs (13%) only funded podium presentations. Twenty-four (63%) have resident research requirements beyond the Accreditation Council for Graduate Medical Education (ACGME) mandate of preparing a "manuscript suitable for publication" prior to graduation. Twenty-five (67%) programs have residents with 2 to 3 active research projects at any given time. None of the investigated resources were significantly associated with increased scholarly output. There was no uniformity to research curricula. Conclusions Otolaryngology residency programs value research, evidenced by financial support provided and requirements beyond the ACGME minimum. Additional resources were not statistically related to an increase in resident research productivity, although they may contribute positively to the overall research experience during training. Potential future areas to examine include research curricula best practices, how to develop meaningful mentorship and resource allocation that inspires continued research interest, and intellectual stimulation.

Design study of underground facility of the Underground Research Laboratory

International Nuclear Information System (INIS)

Hibiya, Keisuke; Akiyoshi, Kenji; Ishizuka, Mineo; Anezaki, Susumu

1998-03-01

Geoscientific research program to study deep geological environment has been performed by Power Reactor and Nuclear Fuel Development Corporation (PNC). This research is supported by 'Long-Term Program for Research, Development and Utilization of Nuclear Energy'. An Underground Research Laboratory is planned to be constructed at Shoma-sama Hora in the research area belonging to PNC. A wide range of geoscientific research and development activities which have been previously studied at the Tono Area is planned in the laboratory. The Underground Research Laboratory is consisted of Surface Laboratory and Underground Research Facility located from the surface down to depth between several hundreds and 1,000 meters. Based on the results of design study in last year, the design study performed in this year is to investigate the followings in advance of studies for basic design and practical design: concept, design procedure, design flow and total layout. As a study for the concept of the underground facility, items required for the facility are investigated and factors to design the primary form of the underground facility are extracted. Continuously, design methods for the vault and the underground facility are summarized. Furthermore, design procedures of the extracted factors are summarized and total layout is studied considering the results to be obtained from the laboratory. (author)

The Laboratories at Seibersdorf: Multi-disciplinary research and support centre

International Nuclear Information System (INIS)

Danesi, P.R.

1987-01-01

The main research activities performed at the IAEA laboratories at Seibersdorf in the Agriculture Laboratory, Physics-Chemistry-Instrumentation Laboratory and Safeguards Analytical Laboratory, as well as the training activities are briefly described

Laboratory Directed Research and Development Program FY 2006 Annual Report

Energy Technology Data Exchange (ETDEWEB)

Sjoreen, Terrence P [ORNL

2007-04-01

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the US Departmental of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, 'Laboratory Directed Research and Development' (April 19, 2006), which establishes DOE's requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2006. The associated FY 2006 ORNL LDRD Self-Assessment (ORNL/PPA-2007/2) provides financial data about the FY 2006 projects and an internal evaluation of the program's management process.

Laboratory Directed Research and Development Program: FY 2015 Annual Report

Energy Technology Data Exchange (ETDEWEB)

SLAC,

2016-04-04

The Department of Energy (DOE) and the SLAC National Accelerator Laboratory (SLAC) encourage innovation, creativity, originality and quality to maintain the Laboratory’s research activities and staff at the forefront of science and technology. To further advance its scientific research capabilities, the Laboratory allocates a portion of its funds for the Laboratory Directed Research and Development (LDRD) program. With DOE guidance, the LDRD program enables SLAC scientists to make rapid and significant contributions that seed new strategies for solving important national science and technology problems. The LDRD program is conducted using existing research facilities.

Laboratory Directed Research and Development Program Activities for FY 2008.

Energy Technology Data Exchange (ETDEWEB)

Looney,J.P.; Fox, K.

2009-04-01

Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that maintains a primary mission focus the physical sciences, energy sciences, and life sciences, with additional expertise in environmental sciences, energy technologies, and national security. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal year 2008 budget was $531.6 million. There are about 2,800 employees, and another 4,300 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development,' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Developlnent at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. Accordingly, this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2008. BNL expended $12 million during Fiscal Year 2008 in support of 69 projects. The program has two categories, the annual Open Call LDRDs and Strategic LDRDs, which combine to meet the overall objectives of the LDRD Program. Proposals are solicited annually for review and approval concurrent with the next fiscal year, October 1. For the open call for proposals, an LDRD Selection Committee, comprised of the Associate Laboratory Directors (ALDs) for the Scientific Directorates, an equal number of scientists recommended by the Brookhaven Council, plus the Assistant Laboratory Director for Policy and Strategic Planning, review the proposals submitted in response to the solicitation. The Open Can LDRD category emphasizes innovative research concepts

Research at the Oak Ridge National Laboratory (ORNL)

International Nuclear Information System (INIS)

Postma, H.

1980-01-01

The Oak Ridge National Laboratory is a large (5300 people), US-government-funded laboratory, which performs research in many disciplines and in many technological areas. Programs and organization of ORNL are described for the People's Republic of China

Laboratory research irradiators with enhanced security features

International Nuclear Information System (INIS)

Srivastava, Piyush

2016-01-01

Over the years BRIT has developed state of art technology for laboratory research irradiators which are suited most for carrying out research and development works in the fields of radiation processing. These equipment which house radioactive sources up to 14 kCi are having a number of features to meet users requirements. They are manufactured as per the national and International standards of safety codes. The paper deals with design, development and application aspects of laboratory research irradiator called Gamma Chamber and also the new security features planned for incorporation in the equipment. Equipment are being regularly manufactured, supplied and installed by BRIT in India and Abroad. There is a number of such equipment in use at different institutions and are found to be very useful. (author)

Laboratory research irradiators with enhanced security features

International Nuclear Information System (INIS)

Srivastava, Piyush

2014-01-01

Over the years BRIT has developed state of art technology for laboratory research irradiators which are suited most for carrying out research and development works in the fields of radiation processing. These equipment which house radioactive sources up to 14 kCi are having a number of features to meet users requirements. They are manufactured as per the national and International standards of safety codes. The paper deals with design, development and application aspects of laboratory research irradiator called Gamma Chamber and also the new security features planned for incorporation in the equipment. Equipment are being regularly manufactured, supplied and installed by BRIT in India and Abroad. There are a number of such equipment in use at different institutions and are found to be very useful. (author)

Laboratory Directed Research and Development Program Assessment for FY 2008

Energy Technology Data Exchange (ETDEWEB)

Looney, J P; Fox, K J

2008-03-31

Brookhaven National Laboratory (BNL) is a multidisciplinary Laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal Year 2008 spending was $531.6 million. There are approximately 2,800 employees, and another 4,300 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development,' April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. To be a premier scientific Laboratory, BNL must continuously foster groundbreaking scientific research and renew its research agenda. The competition for LDRD funds stimulates Laboratory scientists to think in new and creative ways, which becomes a major factor in achieving and maintaining research excellence and a means to address National needs within the overall mission of the DOE and BNL. By fostering high-risk, exploratory research, the LDRD program helps

The Criticality Safety Information Resource Center (CSIRC) at Los Alamos National Laboratory

International Nuclear Information System (INIS)

Henderson, B.D.; Meade, R.A.; Pruvost, N.L.

1999-01-01

The Criticality Safety Information Resource Center (CSIRC) at Los Alamos National Laboratory (LANL) is a program jointly funded by the U.S. Department of Energy (DOE) and the U.S. Nuclear Regulatory Commission (NRC) in conjunction with the Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 97-2. The goal of CSIRC is to preserve primary criticality safety documentation from U.S. critical experimental sites and to make this information available for the benefit of the technical community. Progress in archiving criticality safety primary documents at the LANL archives as well as efforts to make this information available to researchers are discussed. The CSIRC project has a natural linkage to the International Criticality Safety Benchmark Evaluation Project (ICSBEP). This paper raises the possibility that the CSIRC project will evolve in a fashion similar to the ICSBEP. Exploring the implications of linking the CSIRC to the international criticality safety community is the motivation for this paper

From biomedicine to natural history research: EST resources for ambystomatid salamanders

Directory of Open Access Journals (Sweden)

Bryant Susan V

2004-08-01

Full Text Available Abstract Background Establishing genomic resources for closely related species will provide comparative insights that are crucial for understanding diversity and variability at multiple levels of biological organization. We developed ESTs for Mexican axolotl (Ambystoma mexicanum and Eastern tiger salamander (A. tigrinum tigrinum, species with deep and diverse research histories. Results Approximately 40,000 quality cDNA sequences were isolated for these species from various tissues, including regenerating limb and tail. These sequences and an existing set of 16,030 cDNA sequences for A. mexicanum were processed to yield 35,413 and 20,599 high quality ESTs for A. mexicanum and A. t. tigrinum, respectively. Because the A. t. tigrinum ESTs were obtained primarily from a normalized library, an approximately equal number of contigs were obtained for each species, with 21,091 unique contigs identified overall. The 10,592 contigs that showed significant similarity to sequences from the human RefSeq database reflected a diverse array of molecular functions and biological processes, with many corresponding to genes expressed during spinal cord injury in rat and fin regeneration in zebrafish. To demonstrate the utility of these EST resources, we searched databases to identify probes for regeneration research, characterized intra- and interspecific nucleotide polymorphism, saturated a human – Ambystoma synteny group with marker loci, and extended PCR primer sets designed for A. mexicanum / A. t. tigrinum orthologues to a related tiger salamander species. Conclusions Our study highlights the value of developing resources in traditional model systems where the likelihood of information transfer to multiple, closely related taxa is high, thus simultaneously enabling both laboratory and natural history research.

From biomedicine to natural history research: EST resources for ambystomatid salamanders

Science.gov (United States)

Putta, Srikrishna; Smith, Jeramiah J; Walker, John A; Rondet, Mathieu; Weisrock, David W; Monaghan, James; Samuels, Amy K; Kump, Kevin; King, David C; Maness, Nicholas J; Habermann, Bianca; Tanaka, Elly; Bryant, Susan V; Gardiner, David M; Parichy, David M; Voss, S Randal

2004-01-01

Background Establishing genomic resources for closely related species will provide comparative insights that are crucial for understanding diversity and variability at multiple levels of biological organization. We developed ESTs for Mexican axolotl (Ambystoma mexicanum) and Eastern tiger salamander (A. tigrinum tigrinum), species with deep and diverse research histories. Results Approximately 40,000 quality cDNA sequences were isolated for these species from various tissues, including regenerating limb and tail. These sequences and an existing set of 16,030 cDNA sequences for A. mexicanum were processed to yield 35,413 and 20,599 high quality ESTs for A. mexicanum and A. t. tigrinum, respectively. Because the A. t. tigrinum ESTs were obtained primarily from a normalized library, an approximately equal number of contigs were obtained for each species, with 21,091 unique contigs identified overall. The 10,592 contigs that showed significant similarity to sequences from the human RefSeq database reflected a diverse array of molecular functions and biological processes, with many corresponding to genes expressed during spinal cord injury in rat and fin regeneration in zebrafish. To demonstrate the utility of these EST resources, we searched databases to identify probes for regeneration research, characterized intra- and interspecific nucleotide polymorphism, saturated a human – Ambystoma synteny group with marker loci, and extended PCR primer sets designed for A. mexicanum / A. t. tigrinum orthologues to a related tiger salamander species. Conclusions Our study highlights the value of developing resources in traditional model systems where the likelihood of information transfer to multiple, closely related taxa is high, thus simultaneously enabling both laboratory and natural history research. PMID:15310388

Laboratory Directed Research and Development FY2008 Annual Report

International Nuclear Information System (INIS)

Kammeraad, J.E.; Jackson, K.J.; Sketchley, J.A.; Kotta, P.R.

2009-01-01

The Laboratory Directed Research and Development (LDRD) Program, authorized by Congress in 1991 and administered by the Institutional Science and Technology Office at Lawrence Livermore, is our primary means for pursuing innovative, long-term, high-risk, and potentially high-payoff research that supports the full spectrum of national security interests encompassed by the missions of the Laboratory, the Department of Energy, and National Nuclear Security Administration. The accomplishments described in this annual report demonstrate the strong alignment of the LDRD portfolio with these missions and contribute to the Laboratory's success in meeting its goals. The LDRD budget of $91.5 million for fiscal year 2008 sponsored 176 projects. These projects were selected through an extensive peer-review process to ensure the highest scientific quality and mission relevance. Each year, the number of deserving proposals far exceeds the funding available, making the selection a tough one indeed. Our ongoing investments in LDRD have reaped long-term rewards for the Laboratory and the nation. Many Laboratory programs trace their roots to research thrusts that began several years ago under LDRD sponsorship. In addition, many LDRD projects contribute to more than one mission area, leveraging the Laboratory's multidisciplinary team approach to science and technology. Safeguarding the nation from terrorist activity and the proliferation of weapons of mass destruction will be an enduring mission of this Laboratory, for which LDRD will continue to play a vital role. The LDRD Program is a success story. Our projects continue to win national recognition for excellence through prestigious awards, papers published in peer-reviewed journals, and patents granted. With its reputation for sponsoring innovative projects, the LDRD Program is also a major vehicle for attracting and retaining the best and the brightest technical staff and for establishing collaborations with universities

Laboratory Directed Research and Development annual report, fiscal year 1997

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-03-01

The Department of Energy Order 413.2(a) establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 413.2, LDRD is research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this Order. DOE Order 413.2 requires that each laboratory submit an annual report on its LDRD activities to the cognizant Secretarial Officer through the appropriate Operations Office Manager. The report provided in this document represents Pacific Northwest National Laboratory`s LDRD report for FY 1997.

Signal and Image Processing Research at the Lawrence Livermore National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Roberts, R S; Poyneer, L A; Kegelmeyer, L M; Carrano, C J; Chambers, D H; Candy, J V

2009-06-29

Lawrence Livermore National Laboratory is a large, multidisciplinary institution that conducts fundamental and applied research in the physical sciences. Research programs at the Laboratory run the gamut from theoretical investigations, to modeling and simulation, to validation through experiment. Over the years, the Laboratory has developed a substantial research component in the areas of signal and image processing to support these activities. This paper surveys some of the current research in signal and image processing at the Laboratory. Of necessity, the paper does not delve deeply into any one research area, but an extensive citation list is provided for further study of the topics presented.

NASA Ames Fluid Mechanics Laboratory research briefs

Science.gov (United States)

Davis, Sanford (Editor)

1994-01-01

The Ames Fluid Mechanics Laboratory research program is presented in a series of research briefs. Nineteen projects covering aeronautical fluid mechanics and related areas are discussed and augmented with the publication and presentation output of the Branch for the period 1990-1993.

Pacific Northwest Laboratory annual report for 1987 to the DOE office of energy research: Part 2, Environmental sciences

Energy Technology Data Exchange (ETDEWEB)

1988-07-01

This report summarizes progress in environmental sciences research conducted by Pacific Northwest Laboratory (PNL) for the Office of Health and Environmental Research in FY 1987. Research is directed toward developing a fundamental understanding of processes controlling the long-term fate and biological effects of fugitive chemicals and other stressors resulting from energy development. The research, focused on terrestrial, subsurface, and coastal marine systems, forms the basis for defining and quantifying processes that affect humans and the environment at the regional and global levels. Research is multidisciplinary and multitiered, providing integrated system-level insights into critical environmental processes. Research initiatives in subsurface microbiology and transport, global change, radon, and molecular sciences are building on PNL technical strengths in biogeochemistry, hydrodynamics, molecular biology, and theoretical ecology. Unique PNL facilities are used to probe multiple phenomena complex relationships at increasing levels of complexity. Intermediate-scale experimental systems are used to examine arid land watershed dynamics, aerosol behavior and effects, and multidimensional subsurface transport. In addition, field laboratories (the National Environmental Research Park and Marine Research Laboratory) are used in conjunction with advanced measurement techniques to validate concepts and models, and to extrapolate the results to the system and global levels. Strong university liaisons now in existence are being markedly expanded so that PNL resources and the specialized technical capabilities in the university community can be more efficiently integrated.

Ozone Layer Research and Technical Resources

Science.gov (United States)

Access information on research and technical resources related to ozone layer science. This page provides links to research efforts led by organizations such as the National Oceanic and Atmospheric Administration, the United Nations Environment Program, an

Welded rupture disc assemblies for use in Tritium Research Laboratory

International Nuclear Information System (INIS)

Faltings, R.E.

1976-01-01

Welded rupture disc assemblies were investigated and developed in various ranges for probable use by experimenters in their activities in the Tritium Research Laboratory at Sandia Laboratories, Livermore. This study indicates that currently welded rupture disc assemblies with appropriate testing and installation by certified pressure installers may be used in pressure systems in the Tritium Research Laboratory and other areas at SLL

Bringing the excitement and motivation of research to students; Using inquiry and research-based learning in a year-long biochemistry laboratory : Part II-research-based laboratory-a semester-long research approach using malate dehydrogenase as a research model.

Science.gov (United States)

Knutson, Kristopher; Smith, Jennifer; Nichols, Paul; Wallert, Mark A; Provost, Joseph J

2010-09-01

Research-based learning in a teaching environment is an effective way to help bring the excitement and experience of independent bench research to a large number of students. The program described here is the second of a two-semester biochemistry laboratory series. Here, students are empowered to design, execute and analyze their own experiments for the entire semester. This style of laboratory replaces a variety of shorter labs in favor of an in depth research-based learning experience. The concept is to allow students to function in independent research groups. The research projects are focused on a series of wild-type and mutant clones of malate dehydrogenase. A common research theme for the laboratory helps instructors administer the course and is key to delivering a research opportunity to a large number of students. The outcome of this research-based learning laboratory results in students who are much more confident and skilled in critical areas in biochemistry and molecular biology. Students with research experience have significantly higher confidence and motivation than those students without a previous research experience. We have also found that all students performed better in advanced courses and in the workplace. Copyright © 2010 International Union of Biochemistry and Molecular Biology, Inc.

The Use of Reanalysis Data for Wind Resource Assessment at the National Renewable Energy Laboratory

International Nuclear Information System (INIS)

Elliott, D.; Schwartz, M.; George, R.

1999-01-01

An important component of the National Renewable Energy Laboratory wind resource assessment methodology is the use of available upper-air data to construct detailed vertical profiles for a study region. Currently, the most useful upper-air data for this type of analysis are archived observations from approximately 1800 rawinsonde and pilot balloon stations worldwide. However, significant uncertainty exists in the accuracy of the constructed profiles for many regions. The United States Reanalysis Data Set, recently created by the National Center for Atmospheric Research and the National Centers for Environmental Prediction, has the potential to improve the quality of the vertical profiles. The initial evaluation of the usefulness of the Reanalysis data for wind resource assessment consisted of contrasting reanalysis-derived vertical profiles of the wind characteristics to those generated from upper-air observations for comparable locations. The results indicate that, while reanalysis data can be substituted for upper-air observation data in the assessment methodology for areas of the world where observation data are limited, enough discrepancies with observation data have been noticed to warrant further studies

MSU-DOE Plant Research Laboratory

Energy Technology Data Exchange (ETDEWEB)

1991-01-01

This document is the compiled progress reports of research funded through the Michigan State University/Department of Energy Plant Research Laboratory. Fourteen reports are included, covering the molecular basis of plant/microbe symbiosis, cell wall biosynthesis and proteins, gene expression, stress responses, plant hormone biosynthesis, interactions between the nuclear and organelle genomes, sensory transduction and tropisms, intracellular sorting and trafficking, regulation of lipid metabolism, molecular basis of disease resistance and plant pathogenesis, developmental biology of Cyanobacteria, and hormonal involvement in environmental control of plant growth. 320 refs., 26 figs., 3 tabs. (MHB)

Laboratory Directed Research and Development Program. Annual report

Energy Technology Data Exchange (ETDEWEB)

Ogeka, G.J.

1991-12-01

Today, new ideas and opportunities, fostering the advancement of technology, are occurring at an ever-increasing rate. It, therefore, seems appropriate that a vehicle be available which fosters the development of these new ideas and technologies, promotes the early exploration and exploitation of creative and innovative concepts, and which develops new ``fundable`` R&D projects and programs. At Brookhaven National Laboratory (BNL), one such method is through its Laboratory Directed Research and Development (LDRD) Program. This discretionary research and development tool is critical in maintaining the scientific excellence and vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community, fostering new science and technology ideas, which is the major factor achieving and maintaining staff excellence, and a means to address national needs, with the overall mission of the Department of Energy (DOE) and the Brookhaven National Laboratory. The Project Summaries with their accomplishments described in this report reflect the above. Aside from leading to new fundable or promising programs and producing especially noteworthy research, they have resulted in numerous publications in various professional and scientific journals, and presentations at meetings and forums.

Prediction of Wind Energy Resources (PoWER) Users Guide

Science.gov (United States)

2016-01-01

ARL-TR-7573● JAN 2016 US Army Research Laboratory Prediction of Wind Energy Resources (PoWER) User’s Guide by David P Sauter...manufacturer’s or trade names does not constitute an official endorsement or approval of the use thereof. Destroy this report when it is no longer needed. Do...not return it to the originator. ARL-TR-7573 ● JAN 2016 US Army Research Laboratory Prediction of Wind Energy Resources (PoWER

LABORATORY DIRECTED RESEARCH AND DEVELOPMENT PROGRAM ASSESSMENT FOR FY 2006.

Energy Technology Data Exchange (ETDEWEB)

FOX,K.J.

2006-01-01

Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's total annual budget has averaged about $460 million. There are about 2,500 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, ''Laboratory Directed Research and Development,'' April 19,2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy National Nuclear Security Administration Laboratories dated June 13,2006. The goals and' objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new

Laboratory Directed Research and Development Program Assessment for FY 2007

Energy Technology Data Exchange (ETDEWEB)

Newman,L.; Fox, K.J.

2007-12-31

Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal Year 2007 spending was $515 million. There are approximately 2,600 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development', April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology ideas, which

Laboratory Directed Research and Development annual report, Fiscal year 1993

International Nuclear Information System (INIS)

1994-01-01

The Department of Energy Order DOE 5000.4A establishes DOE's policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 5000.4A, LDRD is ''research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this Order. LDRD includes activities previously defined as ER ampersand D, as well as other discretionary research and development activities not provided for in a DOE program.'' Consistent with the Mission Statement and Strategic Plan provided in PNL's Institutional Plan, the LDRD investments are focused on developing new and innovative approaches in research related to our ''core competencies.'' Currently, PNL's core competencies have been identified as integrated environmental research; process technology; energy systems research. In this report, the individual summaries of Laboratory-level LDRD projects are organized according to these core competencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. A significant proportion of PNL's LDRD funds are also allocated to projects within the various research centers that are proposed by individual researchers or small research teams. The projects are described in Section 2.0. The projects described in this report represent PNL's investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. In accordance with DOE guidelines, the report provides an overview of PNL's LDRD program and the management process used for the program and project summaries for each LDRD project

Laboratory Directed Research and Development annual report, Fiscal year 1993

Energy Technology Data Exchange (ETDEWEB)

1994-01-01

The Department of Energy Order DOE 5000.4A establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 5000.4A, LDRD is ``research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this Order. LDRD includes activities previously defined as ER&D, as well as other discretionary research and development activities not provided for in a DOE program.`` Consistent with the Mission Statement and Strategic Plan provided in PNL`s Institutional Plan, the LDRD investments are focused on developing new and innovative approaches in research related to our ``core competencies.`` Currently, PNL`s core competencies have been identified as integrated environmental research; process technology; energy systems research. In this report, the individual summaries of Laboratory-level LDRD projects are organized according to these core competencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. A significant proportion of PNL`s LDRD funds are also allocated to projects within the various research centers that are proposed by individual researchers or small research teams. The projects are described in Section 2.0. The projects described in this report represent PNL`s investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. In accordance with DOE guidelines, the report provides an overview of PNL`s LDRD program and the management process used for the program and project summaries for each LDRD project.

Modular laboratories--cost-effective and sustainable infrastructure for resource-limited settings.

Science.gov (United States)

Bridges, Daniel J; Colborn, James; Chan, Adeline S T; Winters, Anna M; Dengala, Dereje; Fornadel, Christen M; Kosloff, Barry

2014-12-01

High-quality laboratory space to support basic science, clinical research projects, or health services is often severely lacking in the developing world. Moreover, the construction of suitable facilities using traditional methods is time-consuming, expensive, and challenging to implement. Three real world examples showing how shipping containers can be converted into modern laboratories are highlighted. These include use as an insectary, a molecular laboratory, and a BSL-3 containment laboratory. These modular conversions have a number of advantages over brick and mortar construction and provide a cost-effective and timely solution to offer high-quality, user-friendly laboratory space applicable within the developing world. © The American Society of Tropical Medicine and Hygiene.

Multiple-use plasma laboratory for graduate fusion education

International Nuclear Information System (INIS)

Hankins, O.E.; Gilligan, J.G.; Wehring, B.W.; Bourham, M.; Auciello, O.H.

1989-01-01

In a climate of tight fusion research and teaching laboratory budgets, it has become necessary to utilize equipment obtained for research purposes in the teaching program. Likewise, it is desirable to use plasma research equipment from nonfusion projects to support basic understanding of general plasma concepts. Multiple experiments can also be done on a single device. The plasma laboratory that has been developed at North Carolina State University in the last 4 yr incorporates all of the aforementioned ideas to support a 3-credit-hour hands-on laboratory course for graduate students. Incorporating teaching and research into the fusion plasma laboratory maximizes the resources and gives students experience on actual research tools. 2 refs

Laboratory Directed Research and Development FY2008 Annual Report

Energy Technology Data Exchange (ETDEWEB)

Kammeraad, J E; Jackson, K J; Sketchley, J A; Kotta, P R

2009-03-24

The Laboratory Directed Research and Development (LDRD) Program, authorized by Congress in 1991 and administered by the Institutional Science and Technology Office at Lawrence Livermore, is our primary means for pursuing innovative, long-term, high-risk, and potentially high-payoff research that supports the full spectrum of national security interests encompassed by the missions of the Laboratory, the Department of Energy, and National Nuclear Security Administration. The accomplishments described in this annual report demonstrate the strong alignment of the LDRD portfolio with these missions and contribute to the Laboratory's success in meeting its goals. The LDRD budget of $91.5 million for fiscal year 2008 sponsored 176 projects. These projects were selected through an extensive peer-review process to ensure the highest scientific quality and mission relevance. Each year, the number of deserving proposals far exceeds the funding available, making the selection a tough one indeed. Our ongoing investments in LDRD have reaped long-term rewards for the Laboratory and the nation. Many Laboratory programs trace their roots to research thrusts that began several years ago under LDRD sponsorship. In addition, many LDRD projects contribute to more than one mission area, leveraging the Laboratory's multidisciplinary team approach to science and technology. Safeguarding the nation from terrorist activity and the proliferation of weapons of mass destruction will be an enduring mission of this Laboratory, for which LDRD will continue to play a vital role. The LDRD Program is a success story. Our projects continue to win national recognition for excellence through prestigious awards, papers published in peer-reviewed journals, and patents granted. With its reputation for sponsoring innovative projects, the LDRD Program is also a major vehicle for attracting and retaining the best and the brightest technical staff and for establishing collaborations with

Laboratory and cyclotron requirements for PET research

International Nuclear Information System (INIS)

Schlyer, D.J.

1993-01-01

The requirements for carrying out PET research can vary widely depending on the type of basic research being carried out and the extent of a clinical program at a particular center. The type of accelerator and laboratory facilities will, of course, depend on the exact mix. These centers have been divided into four categories. 1. Clinical PET with no radionuclide production facilities, 2. clinical PET with some radionuclide production facilities, 3. clinical PET with research support, and 4. a PET research facility developing new tracers and exploring clinical applications. Guidelines for the choice of an accelerator based on these categories and the practical yields of the common nuclear reactions for production of PET isotopes have been developed and are detailed. Guidelines as to the size and physical layout of the laboratory space necessary for the synthesis of various radiopharmaceuticals have also been developed and are presented. Important utility and air flow considerations are explored

Laboratory directed research and development annual report: Fiscal year 1992

International Nuclear Information System (INIS)

1993-01-01

The Department of Energy Order DOE 5000.4A establishes DOE's policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 5000.4A, LDRD is ''research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this order. Consistent with the Mission Statement and Strategic Plan provided in PNL's Institutional Plan, the LDRD investments are focused on developing new and innovative approaches to research related to our ''core competencies.'' Currently, PNL's core competencies have been identified as: integrated environmental research; process science and engineering; energy distribution and utilization. In this report, the individual summaries of Laboratory-level LDRD projects are organized according to these corecompetencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. The projects described in this report represent PNL's investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. The report provides an overview of PNL's LDRD program and the management process used for the program and project summaries for each LDRD project

ORNLs Laboratory Directed Research and Development Program FY 2010 Annual Report

Energy Technology Data Exchange (ETDEWEB)

None, None

2011-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2010. The associated FY 2010 ORNL LDRD Self-Assessment (ORNL/PPA-2011/2) provides financial data and an internal evaluation of the program’s management process.

ORNLs Laboratory Directed Research and Development Program FY 2009 Annual Report

Energy Technology Data Exchange (ETDEWEB)

None, None

2010-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2009. The associated FY 2009 ORNL LDRD Self-Assessment (ORNL/PPA-2010/2) provides financial data and an internal evaluation of the program’s management process.

ORNLs Laboratory Directed Research and Development Program FY 2008 Annual Report

Energy Technology Data Exchange (ETDEWEB)

None, None

2009-03-01

The Oak Ridge National Laboratory (ORNL) Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries all ORNL LDRD research activities supported during FY 2008. The associated FY 2008 ORNL LDRD Self-Assessment (ORNL/PPA-2008/2) provides financial data and an internal evaluation of the program’s management process.

ORNLs Laboratory Directed Research and Development Program FY 2013 Annual Report

Energy Technology Data Exchange (ETDEWEB)

None, None

2014-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2013. The associated FY 2013 ORNL LDRD Self-Assessment (ORNL/PPA-2014/2) provides financial data and an internal evaluation of the program’s management process.

ORNLs Laboratory Directed Research and Development Program FY 2012 Annual Report

Energy Technology Data Exchange (ETDEWEB)

None, None

2013-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the US Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2012. The associated FY 2012 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial data and an internal evaluation of the program’s management process.

ORNLs Laboratory Directed Research and Development Program FY 2011 Annual Report

Energy Technology Data Exchange (ETDEWEB)

None, None

2012-03-01

The Laboratory Directed Research and Development (LDRD) program at Oak Ridge National Laboratory (ORNL) reports its status to the U.S. Department of Energy (DOE) in March of each year. The program operates under the authority of DOE Order 413.2B, “Laboratory Directed Research and Development” (April 19, 2006), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. LDRD funds are obtained through a charge to all Laboratory programs. This report includes summaries of all ORNL LDRD research activities supported during FY 2011. The associated FY 2011 ORNL LDRD Self-Assessment (ORNL/PPA-2012/2) provides financial data and an internal evaluation of the program’s management process.

Pacific Northwest National Laboratory Institutional Plan FY 2001-2005

Energy Technology Data Exchange (ETDEWEB)

Fisher, Darrell R.; Pearson, Erik W.

2000-12-29

The Pacific Northwest National Laboratory Institutional Plan for FY 2001-2005 sets forth the laboratory's mission, roles, technical capabilities, and laboratory strategic plan. In the plan, major initiatives also are proposed and the transitioning initiatives are discussed. The Programmatic Strategy section details our strategic intent, roles, and research thrusts in each of the U.S. Department of Energy's mission areas. The Operations/Infrastructure Strategic Plan section includes information on the laboratory's human resources; environment, safety, and health management; safeguards and security; site and facilities management; information resources management; managaement procatices and standards; and communications and trust.

Pacific Northwest National Laboratory Institutional Plan FY 2000-2004

Energy Technology Data Exchange (ETDEWEB)

Pearson, Erik W.

2000-03-01

The Pacific Northwest National Laboratory Institutional Plan for FY 2000-2004 sets forth the laboratory's mission, roles, technical capabilities, and laboratory strategic plan. In the plan, major initiatives also are proposed and the transitioning initiatives are discussed. The Programmatic Strategy section details our strategic intent, roles, and research thrusts in each of the U.S. Department of Energy's mission areas. The Operations/Infrastructure Strategic Plan section includes information on the laboratory's human resources; environment, safety, and health management; safeguards and security; site and facilities management; information resources management; management practices and standards; and communications and trust.

A professional development model for medical laboratory scientists working in the microbiology laboratory.

Science.gov (United States)

Amerson, Megan H; Pulido, Lila; Garza, Melinda N; Ali, Faheem A; Greenhill, Brandy; Einspahr, Christopher L; Yarsa, Joseph; Sood, Pramilla K; Hu, Peter C

2012-01-01

The University of Texas M.D. Anderson Cancer Center, Division of Pathology and Laboratory Medicine is committed to providing the best pathology and medicine through: state-of-the art techniques, progressive ground-breaking research, education and training for the clinical diagnosis and research of cancer and related diseases. After surveying the laboratory staff and other hospital professionals, the Department administrators and Human Resource generalists developed a professional development model for Microbiology to support laboratory skills, behavior, certification, and continual education within its staff. This model sets high standards for the laboratory professionals to allow the labs to work at their fullest potential; it provides organization to training technologists based on complete laboratory needs instead of training technologists in individual areas in which more training is required if the laboratory needs them to work in other areas. This model is a working example for all microbiology based laboratories who want to set high standards and want their staff to be acknowledged for demonstrated excellence and professional development in the laboratory. The PDM model is designed to focus on the needs of the laboratory as well as the laboratory professionals.

Rutherford Appleton Laboratory 1983

Energy Technology Data Exchange (ETDEWEB)

Elliott, R T; Wroath, P D [eds.

1984-01-01

Efforts are summarized in the areas of: cosmic research; solar and interplanetary research; space plasma science; atmospheric research; distributed computing systems; industrial robotics; software engineering; advanced computer networking (Project UNIVERSE); computing applications in engineering; pattern analysis; electron beam lithography; radio research; applied superconductivity; particle physics; neutron beam research; laser research; and computing facilities and operations. Laboratory resources are summarized, and publications and reports resulting from the work reported for the year are listed, as well as lectures and meetings. (LEW)

Laboratory Directed Research and Development Program Activities for FY 2007.

Energy Technology Data Exchange (ETDEWEB)

Newman,L.

2007-12-31

Brookhaven National Laboratory (BNL) is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, (BSA) under contract with the U. S. Department of Energy (DOE). BNL's Fiscal year 2007 budget was $515 million. There are about 2,600 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 413.2B, 'Laboratory Directed Research and Development', April 19, 2006, and the Roles, Responsibilities, and Guidelines for Laboratory Directed Research and Development at the Department of Energy/National Nuclear Security Administration Laboratories dated June 13, 2006. In accordance this is our Annual Report in which we describe the Purpose, Approach, Technical Progress and Results, and Specific Accomplishments of all LDRD projects that received funding during Fiscal Year 2007. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new 'fundable' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research 'which could lead to new programs, projects, and directions' for the Laboratory. We explicitly indicate that research conducted under the LDRD Program should be highly innovative, and an element of high risk as to success is acceptable. In the solicitation for new proposals for Fiscal Year 2007 we especially requested innovative new projects in

Biological and Environmental Research Program at Oak Ridge National Laboratory, FY 1992--1994

International Nuclear Information System (INIS)

1992-01-01

This report is the 1992--1994 Program Director's Overview Report for Oak Ridge National Laboratory's (ORNL's) Biological and Environmental Research (BER) Program, and as such it addresses KP-funded work at ORNL conducted during FY 1991 and in progress during FY 1992; it also serves as a planning document for the remainder of FY 1992 through FY 1994. Non-BER funded work at ORNL relevant to the mission of OHER is also discussed. The second section of the report describes ORNL facilities and resources used by the BER program. The third section addresses research management practices at ORNL. The fourth, fifth, and sixth sections address BER-funded research in progress, program accomplishments and research highlights, and program orientation for the remainder of FY 1992 through FY 1994, respectively. Work for non-BER sponsors is described in the seventh section, followed by a discussion of significant near and long-term issues facing BER work at ORNL in the eighth section. The last section provides a statistical summary of BER research at ORNL. Appendices supplement the above topics with additional detail

Idaho National Laboratory Cultural Resource Monitoring Report for Fiscal Year 2007

International Nuclear Information System (INIS)

Brenda R. Pace

2007-01-01

This report describes the cultural resource monitoring activities of the Idaho National Laboratory's (INL) Cultural Resource Management (CRM) Office during fiscal year 2007 (FY 2007). In FY 2007, 40 localities were revisited: two locations of heightened Shoshone-Bannock tribal sensitivity, four caves, three butte/craters, twelve prehistoric archaeological sites, two historic stage stations, nine historic homesteads, a portion of Goodale's Cutoff of the Oregon Trail, a portion of historic trail T-16, one World War II dump, four buildings from the World War II period, and Experimental Breeder Reactor-I, a modern scientific facility and National Historic Landmark. Several INL project areas were also monitored in FY 2007. This included direct observation of ground disturbing activities within the Power Burst Facility (PBF, now designated as the Critical Infrastructure Test Range Complex-CITRC), backfilling operations associated with backhoe trenches along the Big Lost River, and geophysical surveys designed to pinpoint subsurface unexploded ordnance in the vicinity of the Naval Ordnance Disposal Area. Surprise checks were also made to three ongoing INL projects to ensure compliance with INL CRM Office recommendations to avoid impacts to cultural resources. Although some impacts were documented, no significant adverse effects that would threaten the National Register eligibility of any resource were observed at any location

2015 Fermilab Laboratory Directed Research & Development Program Plan

Energy Technology Data Exchange (ETDEWEB)

Wester, W., editor

2015-05-26

Fermilab is executing Laboratory Directed Research and Development (LDRD) as outlined by order DOE O 413.2B in order to enhance and realize the mission of the laboratory in a manner that also supports the laboratory’s strategic objectives and the mission of the Department of Energy. LDRD funds enable scientific creativity, allow for exploration of “high risk, high payoff” research, and allow for the demonstration of new ideas, technical concepts, and devices. LDRD also has an objective of maintaining and enhancing the scientific and technical vitality of Fermilab.

2014 Fermilab Laboratory Directed Research & Development Program Plan

Energy Technology Data Exchange (ETDEWEB)

Wester, W., editor

2016-05-26

Fermilab is executing Laboratory Directed Research and Development (LDRD) as outlined by order DOE O 413.2B in order to enhance and realize the mission of the laboratory in a manner that also supports the laboratory’s strategic objectives and the mission of the Department of Energy. LDRD funds enable scientific creativity, allow for exploration of “high risk, high payoff” research, and allow for the demonstration of new ideas, technical concepts, and devices. LDRD also has an objective of maintaining and enhancing the scientific and technical vitality of Fermilab.

Laboratory directed research and development annual report: Fiscal year 1992

Energy Technology Data Exchange (ETDEWEB)

1993-01-01

The Department of Energy Order DOE 5000.4A establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 5000.4A, LDRD is ``research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this order. Consistent with the Mission Statement and Strategic Plan provided in PNL`s Institutional Plan, the LDRD investments are focused on developing new and innovative approaches to research related to our ``core competencies.`` Currently, PNL`s core competencies have been identified as: integrated environmental research; process science and engineering; energy distribution and utilization. In this report, the individual summaries of Laboratory-level LDRD projects are organized according to these corecompetencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. The projects described in this report represent PNL`s investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. The report provides an overview of PNL`s LDRD program and the management process used for the program and project summaries for each LDRD project.

Laboratory directed research and development annual report: Fiscal year 1992

Energy Technology Data Exchange (ETDEWEB)

1993-01-01

The Department of Energy Order DOE 5000.4A establishes DOE's policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. As described in 5000.4A, LDRD is research and development of a creative and innovative nature which is selected by the Laboratory Director or his or her designee, for the purpose of maintaining the scientific and technological vitality of the Laboratory and to respond to scientific and technological opportunities in conformance with the guidelines in this order. Consistent with the Mission Statement and Strategic Plan provided in PNL's Institutional Plan, the LDRD investments are focused on developing new and innovative approaches to research related to our core competencies.'' Currently, PNL's core competencies have been identified as: integrated environmental research; process science and engineering; energy distribution and utilization. In this report, the individual summaries of Laboratory-level LDRD projects are organized according to these corecompetencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. The projects described in this report represent PNL's investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. The report provides an overview of PNL's LDRD program and the management process used for the program and project summaries for each LDRD project.

JV Task 120 - Coal Ash Resources Research Consortium Research

Energy Technology Data Exchange (ETDEWEB)

Debra Pflughoeft-Hassett; Loreal Heebink; David Hassett; Bruce Dockter; Kurt Eylands; Tera Buckley; Erick Zacher

2009-03-28

The Coal Ash Resources Research Consortium{reg_sign} (CARRC{reg_sign}, pronounced 'cars') is the core coal combustion product (CCP) research group at the Energy & Environmental Research Center (EERC). CARRC focuses on performing fundamental and applied scientific and engineering research emphasizing the environmentally safe, economical use of CCPs. CARRC member organizations, which include utilities and marketers, are key to developing industry-driven research in the area of CCP utilization and ensuring its successful application. The U.S. Department of Energy is a partner in CARRC through the EERC Jointly Sponsored Research Program, which provides matching funds for industrial member contributions and facilitates an increased level of effort in CARRC. CARRC tasks were designed to provide information on CCP performance, including environmental performance, engineering performance, favorable economics, and improved life cycle of products and projects. CARRC technical research tasks are developed based on member input and prioritization. CARRC special projects are developed with members and nonmembers to provide similar information and to support activities, including the assembly and interpretation of data, support for standards development and technology transfer, and facilitating product development and testing. CARRC activities from 2007 to 2009 included a range of research tasks, with primary work performed in laboratory tasks developed to answer specific questions or evaluate important fundamental properties of CCPs. The tasks were included in four categories: (1) Environmental Evaluations of CCPs; (2) Evaluation of Impacts on CCPs from Emission Controls; (3) Construction and Product-Related Activities; and (4) Technology Transfer and Maintenance Tasks. All tasks are designed to work toward achieving the CARRC overall goal and supporting objectives. The various tasks are coordinated in order to provide broad and useful technical data for CARRC members

Effect of Virtual Analytical Chemistry Laboratory on Enhancing Student Research Skills and Practices

Science.gov (United States)

Bortnik, Boris; Stozhko, Natalia; Pervukhina, Irina; Tchernysheva, Albina; Belysheva, Galina

2017-01-01

This article aims to determine the effect of a virtual chemistry laboratory on university student achievement. The article describes a model of a laboratory course that includes a virtual component. This virtual component is viewed as a tool of student pre-lab autonomous learning. It presents electronic resources designed for a virtual laboratory…

Water Resources Research Institute | Mississippi State University

Science.gov (United States)

Welcome The Mississippi Water Resources Research Institute provides a statewide center of expertise in water and associated land-use and serves as a repository of knowledge for use in education private interests in the conservation, development, and use of water resources; to provide training

Influenza research database: an integrated bioinformatics resource for influenza virus research

Science.gov (United States)

The Influenza Research Database (IRD) is a U.S. National Institute of Allergy and Infectious Diseases (NIAID)-sponsored Bioinformatics Resource Center dedicated to providing bioinformatics support for influenza virus research. IRD facilitates the research and development of vaccines, diagnostics, an...

Scientific and technical publications of the Environmental Research Laboratories: fiscal year 1976 (July 1, 1975 through September 30, 1976)

International Nuclear Information System (INIS)

1977-10-01

The Environmental Research Laboratories (ERL) conduct fundamental investigations needed to improve understanding of the physical environment. The ERL programs include investigation of ocean processes, and their interactions with the atmosphere; studies of the ocean environment as it is affected by waste disposal and development of energy resources; fundamental studies of the upper atmosphere and space environments; lower atmosphere research--the weather and climates; research on tsunamis, severe local storms, and hurricanes; studies of weather modification, and the environmental effects of global pollution or similar ecological factors; and development of equipment, instruments, systems, and facilities for these programs. This report lists the output of ERL in terms of papers and reports for the period July 1, 1975, through September 30, 1976. The list includes all known publications in journals for this period as well as those published within the official report series of the laboratories. Publications resulting from research contracts or grants and work done by cooperating institutes or on international aid programs are included

Environmental Molecular Sciences Laboratory 2004 Annual Report

Energy Technology Data Exchange (ETDEWEB)

White, Julia C.

2005-04-17

This 2004 Annual Report describes the research and accomplishments of staff and users of the W.R. Wiley Environmental Molecular Sciences Laboratory (EMSL), located in Richland, Washington. EMSL is a multidisciplinary, national scientific user facility and research organization, operated by Pacific Northwest National Laboratory (PNNL) for the U.S. Department of Energy's Office of Biological and Environmental Research. The resources and opportunities within the facility are an outgrowth of the U.S. Department of Energy's (DOE) commitment to fundamental research for understanding and resolving environmental and other critical scientific issues.

Roles of coastal laboratories in the implementation of the nation`s emerging priorities for research in the coastal zone: Workshop proceedings

Energy Technology Data Exchange (ETDEWEB)

Malone, T.C. [ed.] [Maryland Univ., Cambridge, MD (United States). Horn Point Environmental Labs.; Brooks, A.S. [ed.] [Wisconsin Univ., Milwaukee, WI (United States). Center for Great Lakes Studies; Clegg, J.S. [ed.] [California Univ., Bodega Bay, CA (United States). Bodega Marine Lab.] [and others

1995-12-31

Rapid growth in the human population and related increases in consumption, depletion of natural resources, and environmental degradation are serious concerns for the quality of life and national security. Global change, biological diversity, and sustainable ecosystems were identified as priority areas of research based on their importance for the advance of the fundamental knowledge needed to manage for a sustainable biosphere. Demographic trends, global climate change, and patterns of contaminant release and transport suggest that the effects of human activity on the environment and on natural resources will be especially pronounced in the coastal zone. This report presents the results of a workshop organized by the National Association of Marine Laboratories (NAML) to evaluate the changing roles of coastal laboratories and to recommend mechanisms by which the community of coastal scientists can more effectively work together and with government agencies in defining priorities and implementing research programs that are responsive to national needs. The workshop is part of an ongoing effort to facilitate more integrated approaches to environmental research and the use of scientific information for the purposes of education and environmental management in the coastal zone.

Global Information Resources on Rice for Research and Development

Directory of Open Access Journals (Sweden)

Shri RAM

2012-12-01

Full Text Available Various issues concerning the progress of rice research are related to ambiguous germplasm identification, difficulty in tracing pedigree information, and lack of integration between genetic resources, characterization, breeding, evaluation and utilization data. These issues are the constraints in developing knowledge-intensive crop improvement programs. The rapid growth, development and the global spread of modern information and communication technology allow quick adoption in fundamental research. Thus, there is a need to provide an opportunity for the establishment of services which describe the rice information for better accessibility to information resources used by researchers to enhance the competitiveness. This work reviews some of available resources on rice bioinformatics and their roles in elucidating and propagating biological and genomic information in rice research. These reviews will also enable stakeholders to understand and adopt the change in research and development and share knowledge with the global community of agricultural scientists. The establishment like International Rice Information System, Rice Genome Research Project and Integrated Rice Genome Explorer are major initiatives for the improvement of rice. Creation of databases for comparative studies of rice and other cereals are major steps in further improvement of genetic compositions. This paper will also highlight some of the initiatives and organizations working in the field of rice improvement and explore the availability of the various web resources for the purpose of research and development of rice. We are developing a meta web server for integration of online resources such as databases, web servers and journals in the area of bioinformatics. This integrated platform, with acronym iBIRA, is available online at ibiranet.in. The resources reviewed here are the excerpts from the resources integrated in iBIRA.

Idaho National Laboratory - Nuclear Research Center

International Nuclear Information System (INIS)

Zaidi, M.K.

2005-01-01

Full text: The Idaho National Laboratory is committed to the providing international nuclear leadership for the 21st Century, developing and demonstrating compiling national security technologies, and delivering excellence in science and technology as one of the United States Department of Energy's (DOE) multiprogram national laboratories. INL runs three major programs - Nuclear, Security and Science. nuclear programs covers the Advanced test reactor, Six Generation technology concepts selected for R and D, Targeting tumors - Boron Neutron capture therapy. Homeland security - Homeland Security establishes the Control System Security and Test Center, Critical Infrastructure Test Range evaluates technologies on a scalable basis, INL conducts high performance computing and visualization research and science - INL facility established for Geocentrifuge Research, Idaho Laboratory, a Utah company achieved major milestone in hydrogen research and INL uses extremophile bacteria to ease bleaching's environmental cost. To provide leadership in the education and training, INL has established an Institute of Nuclear Science and Engineering (Inset). The institute will offer a four year degree based on a newly developed curriculum - two year of basic science course work and two years of participation in project planning and development. The students enrolled in this program can continue to get a masters or a doctoral degree. This summer Inset is the host for the training of the first international group selected by the World Nuclear University (WNU) - 75 fellowship holders and their 30 instructors from 40 countries. INL has been assigned to provide future global leadership in the field of nuclear science and technology. Here, at INL, we keep safety first above all things and our logo is 'Nuclear leadership synonymous with safety leadership'

Facility Design and Health Management Program at the Sinnhuber Aquatic Research Laboratory.

Science.gov (United States)

Barton, Carrie L; Johnson, Eric W; Tanguay, Robert L

2016-07-01

The number of researchers and institutions moving to the utilization of zebrafish for biomedical research continues to increase because of the recognized advantages of this model. Numerous factors should be considered before building a new or retooling an existing facility. Design decisions will directly impact the management and maintenance costs. We and others have advocated for more rigorous approaches to zebrafish health management to support and protect an increasingly diverse portfolio of important research. The Sinnhuber Aquatic Research Laboratory (SARL) is located ∼3 miles from the main Oregon State University campus in Corvallis, Oregon. This facility supports several research programs that depend heavily on the use of adult, larval, and embryonic zebrafish. The new zebrafish facility of the SARL began operation in 2007 with a commitment to build and manage an efficient facility that diligently protects human and fish health. An important goal was to ensure that the facility was free of Pseudoloma neurophilia (Microsporidia), which is very common in zebrafish research facilities. We recognize that there are certain limitations in space, resources, and financial support that are institution dependent, but in this article, we describe the steps taken to build and manage an efficient specific pathogen-free facility.

Environmental survey at Lucas Heights Research Laboratories, 1989

International Nuclear Information System (INIS)

Hoffman, E.L.; Arthur, J.

1990-09-01

Results are presented of an environmental survey conducted in the neighbourhood of the Lucas Heights Research Laboratories during 1989. No radioactivity which could have originated from these laboratories was found in samples collected from possible human food chains. All low-level liquid and gaseous waste discharges were within authorised limits. The maximum possible annual dose to the general public from airborne waste during this period is estimated to be less than 0.01 millisieverts, which is one per cent of the limit for long-term exposure that is recommended by the National Health and Medical Research Council. 9 refs., 17 tabs., 2 figs

Environmental survey at Lucas Heights Research Laboratories, 1990

International Nuclear Information System (INIS)

Hoffmann, E.L.

1991-10-01

Results are presented of an environmental survey conducted in the neighbourhood of the Lucas Heights Research Laboratories during 1990. No radioactivity which could have originated from these laboratories was found in samples collected from possible human food chains. All low-level liquid and gaseous waste discharges were within authorised limits. The maximum possible annual dose to the general public from airborne waste during this period is estimated to be less than 0.01 millisieverts, which is one per cent of the limit for long-term exposure that is recommended by the National Health and Medical Research Council. 11 refs., 16 tabs., 2 figs

Environmental survey at Lucas Heights Research Laboratories, 1987

International Nuclear Information System (INIS)

Giles, M.S.; Foy, J.J.; Hoffmann, E.L.

1989-12-01

Results are presented of an environmental survey conducted in the neighbourhood of the Lucas Heights Research Laboratories during 1987. No radioactivity which could have originated from these laboratories was found in samples collected from possible human food chains. All low-level liquid and gaseous waste discharges were within authorized limits. The maximum possible annual dose to the general public from airborne waste during this period is estimated to be less than 0.01 millisieverts, which is one per cent of the limit for long-term exposure that is recommended by the National Health and Medical Research Council. 9 refs., 18 tabs., 2 figs

Environmental survey at Lucas Heights Research Laboratories, 1984

International Nuclear Information System (INIS)

Giles, M.S.; Dudaitis, A.

1986-12-01

Results are presented of the environmental survey conducted in the neighbourhood of the Lucas Heights Research Laboratories during 1984. These results are satisfactory. No radioactivity which could have originated from these laboratories was found in samples collected from possible human food chains. All low-level liquid and gaseous waste discharges were within authorised limits. The maximum possible annual dose to the general public from airborne waste discharges during this period is estimated to be less than 0.01 millisieverts, which is one per cent of the limit for long-term exposure that is recommended by the National Health and Medical Research Council

Chemistry and materials science progress report. Weapons-supporting research and laboratory directed research and development: FY 1995

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-04-01

This report covers different materials and chemistry research projects carried out a Lawrence Livermore National Laboratory during 1995 in support of nuclear weapons programs and other programs. There are 16 papers supporting weapons research and 12 papers supporting laboratory directed research.

Chemistry and materials science progress report. Weapons-supporting research and laboratory directed research and development: FY 1995

International Nuclear Information System (INIS)

1996-04-01

This report covers different materials and chemistry research projects carried out a Lawrence Livermore National Laboratory during 1995 in support of nuclear weapons programs and other programs. There are 16 papers supporting weapons research and 12 papers supporting laboratory directed research

Geothermal energy. A national proposal for geothermal resources research

Energy Technology Data Exchange (ETDEWEB)

Denton, J.C. (ed.)

1972-01-01

Discussions are given for each of the following topics: (1) importance to the Nation of geothermal resources, (2) budget recommendations, (3) overview of geothermal resources, (4) resource exploration, (5) resource assessment, (6) resource development and production, (7) utilization technology and economics, (8) environmental effects, (9) institutional considerations, and (10) summary of research needs.

Shaft extension design at the Underground Research Laboratory, Pinawa, Manitoba

International Nuclear Information System (INIS)

Kuzyk, G.W.; Ball, A.E.

1991-01-01

AECL Research has constructed an underground laboratory for the research and development required for the Canadian Nuclear Fuel Waste Management Program. The experimental program in the laboratory will contribute to the assessment of the feasibility and safety of nuclear fuel waste disposal deep in stable plutonic rock. In 1988, AECL extended the shaft of the Underground Research Laboratory (URL) from the existing 255 m depth to a depth of 443 m in cooperation with the United States Department of Energy. The project, which involved carrying out research activities while excavation and construction work was in progress, required careful planning. To accommodate the research programs, full-face blasting with a burn cut was used to advance the shaft. Existing facilities at the URL had to be modified to accommodate an expanded underground facility at a new depth. This paper discusses the design criteria, shaft-sinking methods and approaches used to accommodate the research work during this shaft extension project. (11 refs., 11 figs.)

Pacific Northwest Laboratory annual report for 1992 to the DOE Office of Energy Research

International Nuclear Information System (INIS)

Grove, L.K.; Wildung, R.E.

1993-03-01

The 1992 Annual Report from Pacific Northwest Laboratory (PNL) to the US Department of Energy (DOE) describes research in environment and health conducted during fiscal year 1992. This report consists of four volumes oriented to particular segments of the PNL program, describing research performed for the DOE Office of Health and Environmental Research in the Office of Energy Research. The parts of the 1992 Annual Report are: Biomedical Sciences; Environmental Sciences; Atmospheric Sciences; and Physical Sciences. This Report is Part 2: Environmental Sciences. Included in this report are developments in Subsurface Science, Terrestrial Science, Laboratory-Directed Research and Development, Interactions with Educational Institutions, Technology Transfer, Publications, and Presentations. The research is directed toward developing a fundamental understanding of subsurface and terrestrial systems as a basis for both managing these critical resources and addressing environmental problems such as environmental restoration and global change. The Technology Transfer section of this report describes a number of examples in which fundamental research is laying the groundwork for the technology needed to resolve important environmental problems. The Interactions with Educational Institutions section of the report illustrates the results of a long-term, proactive program to make PNL facilities available for university and preuniversity education and to involve educational institutions in research programs. The areas under investigation include the effect of geochemical and physical phenomena on the diversity and function of microorganisms in deep subsurface environments, ways to address subsurface heterogeneity, and ways to determine the key biochemical and physiological pathways (and DNA markers) that control nutrient, water, and energy dynamics in arid ecosystems and the response of these systems to disturbance and climatic change

Pacific Northwest Laboratory annual report for 1992 to the DOE Office of Energy Research

Energy Technology Data Exchange (ETDEWEB)

Grove, L.K. (ed.)

1993-03-01

The 1992 Annual Report from Pacific Northwest Laboratory (PNL) to the US Department of Energy (DOE) describes research in environment and health conducted during fiscal year 1992. This report consists of four volumes oriented to particular segments of the PNL program, describing research performed for the DOE Office of Health and Environmental Research in the Office of Energy Research. The parts of the 1992 Annual Report are: Biomedical Sciences; Environmental Sciences; Atmospheric Sciences; and Physical Sciences. This Report is Part II: Environmental Sciences. Included in this report are developments in Subsurface Science, Terrestrial Science, Laboratory-Directed Research and Development, Interactions with Educational Institutions, Technology Transfer, Publications, and Presentations. The research is directed toward developing a fundamental understanding of subsurface and terrestrial systems as a basis for both managing these critical resources and addressing environmental problems such as environmental restoration and global change. The Technology Transfer section of this report describes a number of examples in which fundamental research is laying the groundwork for the technology needed to resolve important environmental problems. The Interactions with Educational Institutions section of the report illustrates the results of a long-term, proactive program to make PNL facilities available for university and preuniversity education and to involve educational institutions in research programs. The areas under investigation include the effect of geochemical and physical phenomena on the diversity and function of microorganisms in deep subsurface environments, ways to address subsurface heterogeneity, and ways to determine the key biochemical and physiological pathways (and DNA markers) that control nutrient, water, and energy dynamics in arid ecosystems and the response of these systems to disturbance and climatic change.

Oak Ridge National Laboratory Institutional Plan, FY 1991--FY 1996

Energy Technology Data Exchange (ETDEWEB)

1991-02-01

The Oak Ridge National Laboratory -- one of DOE's major multiprogram laboratories -- focuses its resources on energy research and development (R D). To be able to meet these R D challenges, the Laboratory must achieve excellence in its operations relative to environmental, safety, and health (ES H) protection and to restore its aging facility infrastructure. ORNL's missions are carried out in compliance with all applicable ES H regulations. The Laboratory conducts applied R D in energy technologies -- in conservation; fission; magnetic fusion; health and environmental protection; waste management; renewable resources; and fossil energy. Experimental and theoretical research is undertaken to investigate fundamental problems in physical, chemical, materials, computational, biomedical, earth, and environmental sciences; to advance scientific knowledge; and to support energy technology R D. ORNL designs, builds, and operates unique research facilities for the benefit of university, industrial, and national laboratory researchers. The Laboratory serves as a catalyst in bringing national and international research elements together for important scientific and technical collaborations. ORNL helps to prepare the scientific and technical work force of the future by offering innovative and varied learning and R D experiences at the Laboratory for students and faculty from preschool level through postdoctoral candidates. The transfer of science and technology to US industries and universities is an integral component of ORNL's R D missions. ORNL also undertakes research and development for non-DOE sponsors when such work is synergistic with DOE mission. 66 figs., 55 tabs.

Oak Ridge National Laboratory Institutional Plan, FY 1991--FY 1996

International Nuclear Information System (INIS)

1991-02-01

The Oak Ridge National Laboratory -- one of DOE's major multiprogram laboratories -- focuses its resources on energy research and development (R ampersand D). To be able to meet these R ampersand D challenges, the Laboratory must achieve excellence in its operations relative to environmental, safety, and health (ES ampersand H) protection and to restore its aging facility infrastructure. ORNL's missions are carried out in compliance with all applicable ES ampersand H regulations. The Laboratory conducts applied R ampersand D in energy technologies -- in conservation; fission; magnetic fusion; health and environmental protection; waste management; renewable resources; and fossil energy. Experimental and theoretical research is undertaken to investigate fundamental problems in physical, chemical, materials, computational, biomedical, earth, and environmental sciences; to advance scientific knowledge; and to support energy technology R ampersand D. ORNL designs, builds, and operates unique research facilities for the benefit of university, industrial, and national laboratory researchers. The Laboratory serves as a catalyst in bringing national and international research elements together for important scientific and technical collaborations. ORNL helps to prepare the scientific and technical work force of the future by offering innovative and varied learning and R ampersand D experiences at the Laboratory for students and faculty from preschool level through postdoctoral candidates. The transfer of science and technology to US industries and universities is an integral component of ORNL's R ampersand D missions. ORNL also undertakes research and development for non-DOE sponsors when such work is synergistic with DOE mission. 66 figs., 55 tabs

Argonne National Laboratory: Laboratory Directed Research and Development FY 1993 program activities. Annual report

Energy Technology Data Exchange (ETDEWEB)

None

1993-12-23

The purposes of Argonne`s Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory`s R&D capabilities, and further the development of its strategic initiatives. Projects are selected from proposals for creative and innovative R&D studies which are not yet eligible for timely support through normal programmatic channels. Among the aims of the projects supported by the Program are establishment of engineering ``proof-of-principle`` assessment of design feasibility for prospective facilities; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these projects are closely associated with major strategic thrusts of the Laboratory as described in Argonne`s Five Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne as indicated in the Laboratory LDRD Plan for FY 1993.

Safety Design Requirements for The Interior Architecture of Scientific Research Laboratories

International Nuclear Information System (INIS)

ElDib, A.A.

2014-01-01

The paper discusses one of the primary objectives of interior architecture design of research laboratories (specially those using radioactive materials) where it should provide a safe, accessible environment for laboratory personnel to conduct their work. A secondary objective is to allow for maximum flexibility for safe research. Therefore, health and safety hazards must be anticipated and carefully evaluated so that protective measures can be incorporated into the interior architectural design of these facilities wherever possible. The interior architecture requirements discussed in this paper illustrate some of the basic health and safety design features required for new and remodeled laboratories.The paper discusses one of the primary objectives of interior architecture design of research laboratories (specially those using radioactive materials) where it should provide a safe, accessible environment for laboratory personnel to conduct their work. A secondary objective is to allow for maximum flexibility for safe research. Therefore, health and safety hazards must be anticipated and carefully evaluated so that protective measures can be incorporated into the interior architectural design of these facilities wherever possible. The interior architecture requirements discussed in this paper illustrate some of the basic health and safety design features required for new and remodeled laboratories.

Verbal protocols as methodological resources: research evidence

Directory of Open Access Journals (Sweden)

Alessandra Baldo

2012-01-01

Full Text Available This article aims at reflecting on the use of verbal protocols as a methodological resource in qualitative research, more specifically on the aspect regarded as the main limitation of a study about lexical inferencing in L2 (BALDO; VELASQUES, 2010: its subjective trait. The article begins with a brief literature review on protocols, followed by a description of the study in which they were employed as methodological resources. Based on that, protocol subjectivity is illustrated through samples of unparalleled data classification, carried out independently by two researchers. In the final section, the path followed to minimize the problem is presented, intending to contribute to improve efficiency in the use of verbal protocols in future research.

Laboratory-directed research and development

International Nuclear Information System (INIS)

Gerstl, S.A.W.; Caughran, A.B.

1992-05-01

This report summarizes progress from the Laboratory-Directed Research and Development (LDRD) program during fiscal year 1991. In addition to a programmatic and financial overview, the report includes progress reports from 230 individual R ampersand D projects in 9 scientific categories: atomic and molecular physics; biosciences; chemistry; engineering and base technologies; geosciences; space sciences, and astrophysics; materials sciences; mathematics and computational sciences; nuclear and particle physics; and plasmas, fluids, and particle beams

Revealing all: misleading self-disclosure rates in laboratory-based online research.

Science.gov (United States)

Callaghan, Diana E; Graff, Martin G; Davies, Joanne

2013-09-01

Laboratory-based experiments in online self-disclosure research may be inadvertently compromising the accuracy of research findings by influencing some of the factors known to affect self-disclosure behavior. Disclosure-orientated interviews conducted with 42 participants in the laboratory and in nonlaboratory settings revealed significantly greater breadth of self-disclosure in laboratory interviews, with message length and intimacy of content also strongly related. These findings suggest that a contrived online setting with a researcher presence may stimulate motivation for greater self-disclosure than would occur naturally in an online environment of an individual's choice. The implications of these findings are that researchers should consider the importance of experimental context and motivation in self-disclosure research.

The Microbial Resource Research Infrastructure MIRRI: Strength through Coordination

Directory of Open Access Journals (Sweden)

Erko Stackebrandt

2015-11-01

Full Text Available Microbial resources have been recognized as essential raw materials for the advancement of health and later for biotechnology, agriculture, food technology and for research in the life sciences, as their enormous abundance and diversity offer an unparalleled source of unexplored solutions. Microbial domain biological resource centres (mBRC provide live cultures and associated data to foster and support the development of basic and applied science in countries worldwide and especially in Europe, where the density of highly advanced mBRCs is high. The not-for-profit and distributed project MIRRI (Microbial Resource Research Infrastructure aims to coordinate access to hitherto individually managed resources by developing a pan-European platform which takes the interoperability and accessibility of resources and data to a higher level. Providing a wealth of additional information and linking to datasets such as literature, environmental data, sequences and chemistry will enable researchers to select organisms suitable for their research and enable innovative solutions to be developed. The current independent policies and managed processes will be adapted by partner mBRCs to harmonize holdings, services, training, and accession policy and to share expertise. The infrastructure will improve access to enhanced quality microorganisms in an appropriate legal framework and to resource-associated data in a more interoperable way.

US Department of Energy Integrated Resource Planning Program: Accomplishments and opportunities

Energy Technology Data Exchange (ETDEWEB)

White, D.L. [Oak Ridge National Lab., TN (United States); Mihlmester, P.E. [Aspen Systems Corp., Oak Ridge, TN (United States)

1993-12-17

The US Department of Energy Integrated Resource Planning Program supports many activities and projects that enhance the process by which utilities assess demand and supply options and, subsequently, evaluate and select resources. The US Department of Energy program coordinates integrated resource planning in risk and regulatory analysis; utility and regional planning; evaluation and verification; information transfer/technological assistance; and demand-side management. Professional staff from the National Renewable Energy Laboratory, Oak Ridge National Laboratory, Lawrence Berkeley Laboratory, and Pacific Northwest Laboratories collaborate with peers and stakeholders, in particular, the National Association of Regulatory Utility Commissioners, and conduct research and activities for the US Department of Energy. Twelve integrated resource planning activities and projects are summarized in this report. The summaries reflect the diversity of planning and research activities supported by the Department. The summaries also reflect the high levels of collaboration and teaming that are required by the Program and practiced by the researchers. It is concluded that the Program is achieving its objectives by encouraging innovation and improving planning and decision making. Furthermore, as the Department continues to implement planned improvements in the Program, the Department is effectively positioned to attain its ambitious goals.

Field manual for ground water reconnaissance. Savannah River Laboratory National Uranium Resource Evaluation Program

International Nuclear Information System (INIS)

Ferguson, R.B.; Price, V.; Baucom, E.I.

1977-01-01

A manual is presented that is intended to direct and coordinate field operations, site selection, groundwater sample collection, and information codes for the Savannah River Laboratory (SRL) contribution to the National Uranium Resource Evaluation (NURE) program. The manual provides public relations information for field sampling teams as well as technical direction

National Renewable Energy Laboratory 2004 Research Review

Energy Technology Data Exchange (ETDEWEB)

2005-03-01

In-depth articles on several NREL technologies and advances, including: aligning quantum dots and related nanoscience and nanotechnology research; using NREL's Advanced Automotive Manikin (ADAM) to help test and design ancillary automotive systems; and harvesting ocean wind to generate electricity with deep-water wind turbines. Also covered are NREL news, research updates, and awards and honors received by the Laboratory.

Assessment of use of library resources on research activities of ...

African Journals Online (AJOL)

Library resources use contribute immensely to the research output of agricultural scientists and also play significant roles in supporting agricultural development but resources are inadequately provided. The main objective of the study was to assess the use of library resources on research activities of scientists in three ...

Exploring the links between quality assurance and laboratory resources. An audit-based study.

Science.gov (United States)

Singh, Navjeevan; Panwar, Aru; Masih, Vipin Fazal; Arora, Vinod K; Bhatia, Arati

2003-01-01

To investigate and rectify the problems related to Ziehl-Neelsen (Z-N) staining in a cytology laboratory in the context of quality assurance. An audit based quality assurance study of 1,421 patients with clinical diagnoses of tubercular lymphadenopathy who underwent fine needle aspiration cytology. Data from 8 months were audited (group 1). Laboratory practices related to selection of smears for Z-N staining were studied. A 2-step corrective measure based on results of the audit was introduced for 2 months (group 2). Results were subjected to statistical analysis using the chi 2 test. Of 1,172 patients in group 1,368 had diagnoses other than tuberculosis. Overall acid-fast bacillus (AFB) positivity was 42%. AFB positivity in 249 patients in group 2 was 89% (P assurance. Solving everyday problems can have far-reaching benefits for the performance of laboratory personnel, resources and work flow.

U.S. Army Research Laboratory Annual Review 2011

Science.gov (United States)

2011-12-01

bioremediation of wastewater. The researchers created a functional atomic circuit with stationary barrier. This “atom circuit” is composed of ultra...high energy content approaching jet propellant (JP)-8/ diesel fuel, are a means to address these demands. The Army Research Laboratory has

Integrating Interdisciplinary Research-Based Experiences in Biotechnology Laboratories

Science.gov (United States)

Iyer, Rupa S.; Wales, Melinda E.

2012-01-01

The increasingly interdisciplinary nature of today's scientific research is leading to the transformation of undergraduate education. In addressing these needs, the University of Houston's College of Technology has developed a new interdisciplinary research-based biotechnology laboratory curriculum. Using the pesticide degrading bacterium,…

Laboratory directed research development annual report. Fiscal year 1996

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-05-01

This document comprises Pacific Northwest National Laboratory`s report for Fiscal Year 1996 on research and development programs. The document contains 161 project summaries in 16 areas of research and development. The 16 areas of research and development reported on are: atmospheric sciences, biotechnology, chemical instrumentation and analysis, computer and information science, ecological science, electronics and sensors, health protection and dosimetry, hydrological and geologic sciences, marine sciences, materials science and engineering, molecular science, process science and engineering, risk and safety analysis, socio-technical systems analysis, statistics and applied mathematics, and thermal and energy systems. In addition, this report provides an overview of the research and development program, program management, program funding, and Fiscal Year 1997 projects.

The Challenges of Developing Research Resources for Leading Vietnamese Universities

Science.gov (United States)

Nguyen, Thi Lan Huong

2013-01-01

This paper examines the challenges of developing research resources for leading Vietnamese universities. The first part of the paper presents the background to the study, including literature review on the challenges to research resources development, and describes the research questions and research methods. The next part provides empirical…

Reactor safety research and development in Chalk River Laboratories

Energy Technology Data Exchange (ETDEWEB)

Nitheanandan, T. [Atomic Energy of Canada Limited, Chalk River, ON (Canada)

2014-07-01

Atomic Energy of Canada Limited's Chalk River Laboratories provides three different services to stakeholders and customers. The first service provided by the laboratory is the implementation of Research and Development (R&D) programs to provide the underlying technological basis of safe nuclear power reactor designs. A significant portion of the Canadian R&D capability in reactor safety resides at Atomic Energy of Canada Limited's Chalk River Laboratories, and this capability was instrumental in providing the science and technology required to aid in the safety design of CANDU power reactors. The second role of the laboratory has been in supporting nuclear facility licensees to ensure the continued safe operation of nuclear facilities, and to develop safety cases to justify continued operation. The licensing of plant life extension is a key industry objective, requiring extensive research on degradation mechanisms, such that safety cases are based on the original safety design data and valid and realistic assumptions regarding the effect of ageing and management of plant life. Recently, Chalk River Laboratories has been engaged in a third role in research to provide the technical basis and improved understanding for decision making by regulatory bodies. The state-of-the-art test facilities in Chalk River Laboratories have been contributing to the R&D needs of all three roles, not only in Canada but also in the international community, thorough Canada's participation in cooperative programs lead by International Atomic Energy Agency and the OECD's Nuclear Energy Agency. (author)

An overview of Quality Management System implementation in a research laboratory

Science.gov (United States)

Molinéro-Demilly, Valérie; Charki, Abdérafi; Jeoffrion, Christine; Lyonnet, Barbara; O'Brien, Steve; Martin, Luc

2018-02-01

The aim of this paper is to show the advantages of implementing a Quality Management System (QMS) in a research laboratory in order to improve the management of risks specific to research programmes and to increase the reliability of results. This paper also presents experience gained from feedback following the implementation of the Quality process in a research laboratory at INRA, the French National Institute for Agronomic Research and details the various challenges encountered and solutions proposed to help achieve smoother adoption of a QMS process. The 7Ms (Management, Measurement, Manpower, Methods, Materials, Machinery, Mother-nature) methodology based on the Ishikawa `Fishbone' diagram is used to show the effectiveness of the actions considered by a QMS, which involve both the organization and the activities of the laboratory. Practical examples illustrate the benefits and improvements observed in the laboratory.

LABORATORY DIRECTED RESEARCH AND DEVELOPMENT PROGRAM ACTIVITIES FOR FY2002.

Energy Technology Data Exchange (ETDEWEB)

FOX,K.J.

2002-12-31

Brookhaven National (BNL) Laboratory is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, under contract with the U. S. Department of Energy. BNL's total annual budget has averaged about $450 million. There are about 3,000 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 4 1 3.2A, ''Laboratory Directed Research and Development,'' January 8, 2001, and the LDRD Annual Report guidance, updated February 12, 1999. The LDRD Program obtains its funds through the Laboratory overhead pool and operates under the authority of DOE Order 413.2A. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R&D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology

Location | Frederick National Laboratory for Cancer Research

Science.gov (United States)

The Frederick National Laboratory for Cancer Research campus is located 50 miles northwest of Washington, D.C., and 50 miles west of Baltimore, Maryland, in Frederick, Maryland. Satellite locations include leased and government facilities extending s

Co-Laboratories: New Arenas for Scientific Work

Directory of Open Access Journals (Sweden)

Mauricio Arroyave Franco

2011-09-01

Full Text Available The laboratories like experimental sites are an important tool in education and research, since they allow understanding better the concepts, as well as construct new knowledge. However, there are disadvantages associated with laboratories: the cost of infrastructure, insufficient availability of equipment and the associate risk with the experimentation in harmful environments for human beings. It is considered that these disadvantages can be mitigated with the use of TICs. This paper presents the development of a web platform for remote access to laboratory resources, it is was developed in the Moodle system, and considers laboratories with diverse characteristics. Access to the devices of each laboratory was developed in different web technologies that were later integrated into the platform. The end result was a platform that meets the needs of access to laboratory facilities independent of web technology used and the own characteristics of each laboratory. The results of this study are expected to be are the basis for more flexible and extensive access to resources EAFIT University laboratory and in the future of Colombia.

Known structure, unknown function: An inquiry-based undergraduate biochemistry laboratory course.

Science.gov (United States)

Gray, Cynthia; Price, Carol W; Lee, Christopher T; Dewald, Alison H; Cline, Matthew A; McAnany, Charles E; Columbus, Linda; Mura, Cameron

2015-01-01

Undergraduate biochemistry laboratory courses often do not provide students with an authentic research experience, particularly when the express purpose of the laboratory is purely instructional. However, an instructional laboratory course that is inquiry- and research-based could simultaneously impart scientific knowledge and foster a student's research expertise and confidence. We have developed a year-long undergraduate biochemistry laboratory curriculum wherein students determine, via experiment and computation, the function of a protein of known three-dimensional structure. The first half of the course is inquiry-based and modular in design; students learn general biochemical techniques while gaining preparation for research experiments in the second semester. Having learned standard biochemical methods in the first semester, students independently pursue their own (original) research projects in the second semester. This new curriculum has yielded an improvement in student performance and confidence as assessed by various metrics. To disseminate teaching resources to students and instructors alike, a freely accessible Biochemistry Laboratory Education resource is available at http://biochemlab.org. © 2015 The Authors Biochemistry and Molecular Biology Education published by Wiley Periodicals, Inc. on behalf of International Union of Biochemistry and Molecular Biology.

A Review of the Marine Fish Resources Research in Kenya and ...

African Journals Online (AJOL)

A Review of the Marine Fish Resources Research in Kenya and influence on Management. ... Western Indian Ocean Journal of Marine Science ... This is a fisheries research and management review paper, and analyzes the research work on fish resources and its usefulness to management of fish resources in Kenya.

The Earth Resources Observation Systems data center's training technical assistance, and applications research activities

Science.gov (United States)

Sturdevant, J.A.

1981-01-01

The Earth Resources Observation Systems (EROS) Data Center (EDO, administered by the U.S. Geological Survey, U.S. Department of the Interior, provides remotely sensed data to the user community and offers a variety of professional services to further the understanding and use of remote sensing technology. EDC reproduces and sells photographic and electronic copies of satellite images of areas throughout the world. Other products include aerial photographs collected by 16 organizations, including the U.S. Geological Survey and the National Aeronautics and Space Administration. Primary users of the remotely sensed data are Federal, State, and municipal government agencies, universities, foreign nations, and private industries. The professional services available at EDC are primarily directed at integrating satellite and aircraft remote sensing technology into the programs of the Department of the Interior and its cooperators. This is accomplished through formal training workshops, user assistance, cooperative demonstration projects, and access to equipment and capabilities in an advanced data analysis laboratory. In addition, other Federal agencies, State and local governments, universities, and the general public can get assistance from the EDC Staff. Since 1973, EDC has contributed to the accelerating growth in development and operational use of remotely sensed data for land resource problems through its role as educator and by conducting basic and applied remote sensing applications research. As remote sensing technology continues to evolve, EDC will continue to respond to the increasing demand for timely information on remote sensing applications. Questions most often asked about EDC's research and training programs include: Who may attend an EDC remote sensing training course? Specifically, what is taught? Who may cooperate with EDC on remote sensing projects? Are interpretation services provided on a service basis? This report attempts to define the goals and

The need for a quality standard for assurance in medical research laboratories

Directory of Open Access Journals (Sweden)

S Cohen

2014-01-01

Full Text Available The objective of this article is to show the results of a research study conducted to evaluate the need for a quality standard specific for medical research laboratories based on the shortfalls of ISO 15189 when used for this purpose. A qualitative research methodology was used, which comprised of collecting data from 20 well-qualified and experienced medical laboratory personnel by means of interviews based on a framework developed from a literature review. The data were analysed by means of a thematic technique and the results were verified by a team of medical researchers. The seven themes arising from the analyses were inflexibility; ambiguity; unfair requirements; inappropriate focus; inadequacy for research; renewal; and acceptance for accreditation. The results indicated that the ISO 15189 standard in its present content does not totally suit medical research laboratories and shows support for the development of a standard specific for research laboratories.

Laboratory specimens and genetic privacy: evolution of legal theory.

Science.gov (United States)

Lewis, Michelle Huckaby

2013-03-01

Although laboratory specimens are an important resource for biomedical research, controversy has arisen when research has been conducted without the knowledge or consent of the individuals who were the source of the specimens. This paper summarizes the most important litigation regarding the research use of laboratory specimens and traces the evolution of legal theory from property claims to claims related to genetic privacy interests. © 2013 American Society of Law, Medicine & Ethics, Inc.

Laboratory Directed Research and Development FY 1998 Progress Report

Energy Technology Data Exchange (ETDEWEB)

John Vigil; Kyle Wheeler

1999-04-01

This is the FY 1998 Progress Report for the Laboratory Directed Research and Development (LDRD) Program at Los Alamos National Laboratory. It gives an overview of the LDRD Program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principle investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic, molecular, optical, and plasma physics, fluids, and particle beams, (5) engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.

Laboratory directed research and development: FY 1997 progress report

Energy Technology Data Exchange (ETDEWEB)

Vigil, J.; Prono, J. [comps.

1998-05-01

This is the FY 1997 Progress Report for the Laboratory Directed Research and Development (LDRD) program at Los Alamos National Laboratory. It gives an overview of the LDRD program, summarizes work done on individual research projects, relates the projects to major Laboratory program sponsors, and provides an index to the principal investigators. Project summaries are grouped by their LDRD component: Competency Development, Program Development, and Individual Projects. Within each component, they are further grouped into nine technical categories: (1) materials science, (2) chemistry, (3) mathematics and computational science, (4) atomic and molecular physics and plasmas, fluids, and particle beams, (5) engineering science, (6) instrumentation and diagnostics, (7) geoscience, space science, and astrophysics, (8) nuclear and particle physics, and (9) bioscience.

Biological and Environmental Research Program at Oak Ridge National Laboratory, FY 1992--1994

Energy Technology Data Exchange (ETDEWEB)

1992-01-01

This report is the 1992--1994 Program Director's Overview Report for Oak Ridge National Laboratory's (ORNL's) Biological and Environmental Research (BER) Program, and as such it addresses KP-funded work at ORNL conducted during FY 1991 and in progress during FY 1992; it also serves as a planning document for the remainder of FY 1992 through FY 1994. Non-BER funded work at ORNL relevant to the mission of OHER is also discussed. The second section of the report describes ORNL facilities and resources used by the BER program. The third section addresses research management practices at ORNL. The fourth, fifth, and sixth sections address BER-funded research in progress, program accomplishments and research highlights, and program orientation for the remainder of FY 1992 through FY 1994, respectively. Work for non-BER sponsors is described in the seventh section, followed by a discussion of significant near and long-term issues facing BER work at ORNL in the eighth section. The last section provides a statistical summary of BER research at ORNL. Appendices supplement the above topics with additional detail.

Laboratory Directed Research and Development Program FY2016 Annual Summary of Completed Projects

Energy Technology Data Exchange (ETDEWEB)

None, None

2017-03-30

ORNL FY 2016 Annual Summary of Laboratory Directed Research and Development Program (LDRD) Completed Projects. The Laboratory Directed Research and Development (LDRD) program at ORNL operates under the authority of DOE Order 413.2C, “Laboratory Directed Research and Development” (October 22, 2015), which establishes DOE’s requirements for the program while providing the Laboratory Director broad flexibility for program implementation. The LDRD program funds are obtained through a charge to all Laboratory programs. ORNL reports its status to DOE in March of each year.

Argonne National Laboratory Annual Report of Laboratory Directed Research and Development Program Activities for FY 1994

Energy Technology Data Exchange (ETDEWEB)

None

1995-02-25

The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory's R and D capabilities, and further the development of its strategic initiatives. Projects are selected from proposals for creative and innovative R and D studies which are not yet eligible for timely support through normal programmatic channels. Among the aims of the projects supported by the Program are establishment of engineering proof-of-principle; assessment of design feasibility for prospective facilities; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these projects are closely associated with major strategic thrusts of the Laboratory as described in Argonne's Five-Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne as indicated in the Laboratory's LDRD Plan for FY 1994. Project summaries of research in the following areas are included: (1) Advanced Accelerator and Detector Technology; (2) X-ray Techniques for Research in Biological and Physical Science; (3) Nuclear Technology; (4) Materials Science and Technology; (5) Computational Science and Technology; (6) Biological Sciences; (7) Environmental Sciences: (8) Environmental Control and Waste Management Technology; and (9) Novel Concepts in Other Areas.

Dietary Supplements: Regulatory Challenges and Research Resources.

Science.gov (United States)

Dwyer, Johanna T; Coates, Paul M; Smith, Michael J

2018-01-04

Many of the scientific and regulatory challenges that exist in research on the safety, quality and efficacy of dietary supplements are common to all countries as the marketplace for them becomes increasingly global. This article summarizes some of the challenges in supplement science and provides a case study of research at the Office of Dietary Supplements at the National Institutes of Health, USA, along with some resources it has developed that are available to all scientists. It includes examples of some of the regulatory challenges faced and some resources for those who wish to learn more about them.

Human Resources for Health Research in Africa | IDRC ...

International Development Research Centre (IDRC) Digital Library (Canada)

Human Resources for Health Research in Africa ... the management of research systems for optimal use of results;; packaging research for policymakers; ... Call for new OWSD Fellowships for Early Career Women Scientists now open.

DESALINATION AND WATER TREATMENT RESEARCH AT SANDIA NATIONAL LABORATORIES.

Energy Technology Data Exchange (ETDEWEB)

Rigali, Mark J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Miller, James E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Altman, Susan J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Biedermann, Laura [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Brady, Patrick Vane. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kuzio, Stephanie P. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Nenoff, Tina M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Rempe, Susan [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2016-11-01

Water is the backbone of our economy - safe and adequate supplies of water are vital for agriculture, industry, recreation, and human consumption. While our supply of water today is largely safe and adequate, we as a nation face increasing water supply challenges in the form of extended droughts, demand growth due to population increase, more stringent health-based regulation, and competing demands from a variety of users. To meet these challenges in the coming decades, water treatment technologies, including desalination, will contribute substantially to ensuring a safe, sustainable, affordable, and adequate water supply for the United States. This overview documents Sandia National Laboratories' (SNL, or Sandia) Water Treatment Program which focused on the development and demonstration of advanced water purification technologies as part of the larger Sandia Water Initiative. Projects under the Water Treatment Program include: (1) the development of desalination research roadmaps (2) our efforts to accelerate the commercialization of new desalination and water treatment technologies (known as the 'Jump-Start Program),' (3) long range (high risk, early stage) desalination research (known as the 'Long Range Research Program'), (4) treatment research projects under the Joint Water Reuse & Desalination Task Force, (5) the Arsenic Water Technology Partnership Program, (6) water treatment projects funded under the New Mexico Small Business Administration, (7) water treatment projects for the National Energy Technology Laboratory (NETL) and the National Renewable Energy Laboratory (NREL), (8) Sandia- developed contaminant-selective treatment technologies, and finally (9) current Laboratory Directed Research and Development (LDRD) funded desalination projects.

Evaluation of the state water-resources research institutes

Science.gov (United States)

Ertel, M.O.

1988-01-01

Water resources research institutes, as authorized by the Water Resources Research Act of 1984 (Public Law 98-242), are located in each state and in the District of Columbia, Guam, Puerto Rico , and the Virgin Islands. Public Law 98-242 mandated an onsite evaluation of each of these institutes to determine whether ' . . .the quality and relevance of its water resources research and its effectiveness as an institution for planning, conducting, and arranging for research warrant its continued support in the national interest. ' The results of these evaluations, which were conducted between September 1985 and June 1987, are summarized. The evaluation teams found that all 54 institutes are meeting the basic objectives of the authorizing legislation in that they: (1) use the grant funds to support research that addresses water problems of state and regional concern; (2) provide opportunities for training of water scientists through student involvement on research projects; and (3) promote the application of research results through preparation of technical reports and contributions to the technical literature. The differences among institutes relate primarily to degrees of effectiveness, and most often are determined by the financial, political, and geographical contexts in which the institutes function and by the quality of their leadership. (Lantz-PTT)

Laboratory directed research and development annual report. Fiscal year 1994

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-02-01

The Department of Energy Order DOE 5000.4A establishes DOE`s policy and guidelines regarding Laboratory Directed Research and Development (LDRD) at its multiprogram laboratories. This report represents Pacific Northwest Laboratory`s (PNL`s) LDRD report for FY 1994. During FY 1994, 161 LDRD projects were selected for support through PNL`s LDRD project selection process. Total funding allocated to these projects was $13.7 million. Consistent with the Mission Statement and Strategic Plan provided in PNL`s Institutional Plan, the LDRD investments are focused on developing new and innovative approaches in research related to our {open_quotes}core competencies.{close_quotes} Currently, PNL`s core competencies have been identified as integrated environmental research; process science and engineering; energy systems development. In this report, the individual summaries of LDRD projects (presented in Section 1.0) are organized according to these core competencies. The largest proportion of Laboratory-level LDRD funds is allocated to the core competency of integrated environmental research. Projects within the three core competency areas were approximately 91.4 % of total LDRD project funding at PNL in FY 1994. A significant proportion of PNL`s LDRD funds are also allocated to projects within the various research centers that are proposed by individual researchers or small research teams. Funding allocated to each of these projects is typically $35K or less. The projects described in this report represent PNL`s investment in its future and are vital to maintaining the ability to develop creative solutions for the scientific and technical challenges faced by DOE and the nation. The report provides an overview of PNL`s LDRD program, the management process used for the program, and project summaries for each LDRD project.

Mouse Genome Informatics (MGI) Is the International Resource for Information on the Laboratory Mouse.

Science.gov (United States)

Law, MeiYee; Shaw, David R

2018-01-01

Mouse Genome Informatics (MGI, http://www.informatics.jax.org/ ) web resources provide free access to meticulously curated information about the laboratory mouse. MGI's primary goal is to help researchers investigate the genetic foundations of human diseases by translating information from mouse phenotypes and disease models studies to human systems. MGI provides comprehensive phenotypes for over 50,000 mutant alleles in mice and provides experimental model descriptions for over 1500 human diseases. Curated data from scientific publications are integrated with those from high-throughput phenotyping and gene expression centers. Data are standardized using defined, hierarchical vocabularies such as the Mammalian Phenotype (MP) Ontology, Mouse Developmental Anatomy and the Gene Ontologies (GO). This chapter introduces you to Gene and Allele Detail pages and provides step-by-step instructions for simple searches and those that take advantage of the breadth of MGI data integration.

Field manual for stream sediment reconnaissance. Savannah River Laboratory National Uranium Resource Evaluation Program

International Nuclear Information System (INIS)

Ferguson, R.B.; Price, V.; Baucom, E.I.

1976-07-01

A manual is presented that is intended to direct and coordinate field operations, site selection, stream sediment sample collection, water sample collection, and information codes for the Savannah River Laboratory (SRL) contribution to the National Uranium Resource Evaluation (NURE) program. The manual provides public relations information for field sampling teams as well as technical direction

Interior Architectural Requirements for Electronic Circuits and its Applications Research Laboratory

International Nuclear Information System (INIS)

ElDib, A.A.

2014-01-01

This paper discusses the pivotal role of the Interior Architecture As one of the scientific disciplines minute to complete the Architectural Sciences, which relied upon the achievement and development of facilities containing scientific research laboratories, in terms of planning and design, particularly those containing biological laboratories using radioactive materials, adding to that, the application of the materials or raw materials commensurate with each discipline of laboratory and its work nature, and by the discussion the processing of design techniques and requirements of interior architecture dealing with Research Laboratory for electronic circuits and their applications with the making of its prototypes

FY2007 Laboratory Directed Research and Development Annual Report

Energy Technology Data Exchange (ETDEWEB)

Craig, W W; Sketchley, J A; Kotta, P R

2008-03-20

The Laboratory Directed Research and Development (LDRD) annual report for fiscal year 2007 (FY07) provides a summary of LDRD-funded projects for the fiscal year and consists of two parts: An introduction to the LDRD Program, the LDRD portfolio-management process, program statistics for the year, and highlights of accomplishments for the year. A summary of each project, submitted by the principal investigator. Project summaries include the scope, motivation, goals, relevance to Department of Energy (DOE)/National Nuclear Security Administration (NNSA) and Lawrence Livermore National Laboratory (LLNL) mission areas, the technical progress achieved in FY07, and a list of publications that resulted from the research in FY07. Summaries are organized in sections by research category (in alphabetical order). Within each research category, the projects are listed in order of their LDRD project category: Strategic Initiative (SI), Exploratory Research (ER), Laboratory-Wide Competition (LW), and Feasibility Study (FS). Within each project category, the individual project summaries appear in order of their project tracking code, a unique identifier that consists of three elements. The first is the fiscal year the project began, the second represents the project category, and the third identifies the serial number of the proposal for that fiscal year.

A 50-year research journey. From laboratory to clinic.

Science.gov (United States)

Ross, John

2009-01-01

Prior important research is not always cited, exemplified by Oswald Avery's pioneering discovery that DNA is the genetic transforming factor; it was not cited by Watson and Crick 10 years later. My first laboratory research (National Institutes of Health 1950s) resulted in the clinical development of transseptal left heart catheterization. Laboratory studies on cardiac muscle mechanics in normal and failing hearts led to the concept of afterload mismatch with limited preload reserve. At the University of California, San Diego in La Jolla (1968) laboratory experiments on coronary artery reperfusion after sustained coronary occlusion showed salvage of myocardial tissue, a potential treatment for acute myocardial infarction proven in clinical trials of thrombolysis 14 years later. Among 60 trainees who worked with me in La Jolla, one-third were Japanese and some of their important laboratory experiments are briefly recounted, beginning with Sasayama, Tomoike and Shirato in the 1970 s. Recently, we developed a method for cardiac gene transfer, and subsequently we showed that gene therapy for the defect in cardiomyopathic hamsters halted the progression of advanced disease. Cardiovascular research and medicine are producing continuing advances in technologies for gene transfer and embryonic stem cell transplantation, targeting of small molecules, and tissue and organ engineering.

Hazardous waste management in research laboratories

International Nuclear Information System (INIS)

Sundstrom, G.

1989-01-01

Hazardous waste management in research laboratories benefits from a fundamentally different approach to the hazardous waste determination from industry's. This paper introduces new, statue-based criteria for identifying hazardous wastes (such as radiological mixed wastes and waste oils) and links them to a forward-looking compliance of laboratories, the overall system integrates hazardous waste management activities with other environmental and hazard communication initiatives. It is generalizable to other waste generators, including industry. Although only the waste identification and classification aspects of the system are outlined in detail here, four other components are defined or supported, namely: routine and contingency practices; waste treatment/disposal option definition and selection; waste minimization, recycling, reuse, and substitution opportunities; and key interfaces with other systems, including pollution prevention

Environmental survey at Lucas Heights Research Laboratories, 1993

International Nuclear Information System (INIS)

Hoffmann, E.L.; Looz, T.

1995-04-01

Results are presented of the environmental survey conducted in the neighbourhood of the Lucas Heights Research Laboratories during 1993. No activity which could have originated from these laboratories was found in samples collected from possible human food chains. All low-level liquid and gaseous waste discharges were within authorised limits. The maximum possible annual dose to the general public from airborne discharges during this period is estimated to be less than 0.01 mSv, which is one per cent of the dose limit for long term exposure that is recommended by the National Health and Medical Research Council. A list of previous environmental survey reports is attached. 22 refs., 21 tabs., 4 figs

Laboratory Directed Research and Development Annual Report for 2009

International Nuclear Information System (INIS)

Hughes, Pamela J.

2010-01-01

This report documents progress made on all LDRD-funded projects during fiscal year 2009. As a US Department of Energy (DOE) Office of Science (SC) national laboratory, Pacific Northwest National Laboratory (PNNL) has an enduring mission to bring molecular and environmental sciences and engineering strengths to bear on DOE missions and national needs. Their vision is to be recognized worldwide and valued nationally for leadership in accelerating the discovery and deployment of solutions to challenges in energy, national security, and the environment. To achieve this mission and vision, they provide distinctive, world-leading science and technology in: (1) the design and scalable synthesis of materials and chemicals; (2) climate change science and emissions management; (3) efficient and secure electricity management from generation to end use; and (4) signature discovery and exploitation for threat detection and reduction. PNNL leadership also extends to operating EMSL: the Environmental Molecular Sciences Laboratory, a national scientific user facility dedicated to providing itnegrated experimental and computational resources for discovery and technological innovation in the environmental molecular sciences.

Laboratory Directed Research and Development Annual Report for 2009

Energy Technology Data Exchange (ETDEWEB)

Hughes, Pamela J.

2010-03-31

This report documents progress made on all LDRD-funded projects during fiscal year 2009. As a US Department of Energy (DOE) Office of Science (SC) national laboratory, Pacific Northwest National Laboratory (PNNL) has an enduring mission to bring molecular and environmental sciences and engineering strengths to bear on DOE missions and national needs. Their vision is to be recognized worldwide and valued nationally for leadership in accelerating the discovery and deployment of solutions to challenges in energy, national security, and the environment. To achieve this mission and vision, they provide distinctive, world-leading science and technology in: (1) the design and scalable synthesis of materials and chemicals; (2) climate change science and emissions management; (3) efficient and secure electricity management from generation to end use; and (4) signature discovery and exploitation for threat detection and reduction. PNNL leadership also extends to operating EMSL: the Environmental Molecular Sciences Laboratory, a national scientific user facility dedicated to providing itnegrated experimental and computational resources for discovery and technological innovation in the environmental molecular sciences.

Oversight of High-Containment Biological Laboratories: Issues for Congress

Science.gov (United States)

2009-05-04

Laboratories: Issues for Congress Congressional Research Service 14 Industry and Non-Profit Laboratories Private sector companies and non-profit...resources for these endeavors. Whether public or private sector , high-containment laboratories are planned and designed to minimize the possibility of... equine encephalitis, and yellow fever. Some of the pathogens that cause these diseases have been considered as biological weapons.104 Expanding the number

Critical and strategic materials proceedings of the laboratory study group meeting

International Nuclear Information System (INIS)

1983-06-01

These Proceedings serve to identify the appropriate role for the DOE-BES-DMS Laboratory program concerning critical and strategic materials, identify and articulate high priority DOE-BES-DMS target areas so as to maximize programmatic responsiveness to national needs concerning critical and strategic materials, and identify research, expertise, and resources (including Collaborative Research Centers) that are relevant to critical and strategic materials that is either underway or in place under the DOE-BES-DMS Laboratory program. Laboratory statements of collaborative research are given

Laboratory Directed Research and Development FY2010 Annual Report

Energy Technology Data Exchange (ETDEWEB)

Jackson, K J

2011-03-22

A premier applied-science laboratory, Lawrence Livermore National Laboratory (LLNL) has at its core a primary national security mission - to ensure the safety, security, and reliability of the nation's nuclear weapons stockpile without nuclear testing, and to prevent and counter the spread and use of weapons of mass destruction: nuclear, chemical, and biological. The Laboratory uses the scientific and engineering expertise and facilities developed for its primary mission to pursue advanced technologies to meet other important national security needs - homeland defense, military operations, and missile defense, for example - that evolve in response to emerging threats. For broader national needs, LLNL executes programs in energy security, climate change and long-term energy needs, environmental assessment and management, bioscience and technology to improve human health, and for breakthroughs in fundamental science and technology. With this multidisciplinary expertise, the Laboratory serves as a science and technology resource to the U.S. government and as a partner with industry and academia. This annual report discusses the following topics: (1) Advanced Sensors and Instrumentation; (2) Biological Sciences; (3) Chemistry; (4) Earth and Space Sciences; (5) Energy Supply and Use; (6) Engineering and Manufacturing Processes; (7) Materials Science and Technology; Mathematics and Computing Science; (8) Nuclear Science and Engineering; and (9) Physics.

77 FR 26069 - Joint Biomedical Laboratory Research and Development and Clinical Science Research and...

Science.gov (United States)

2012-05-02

... DEPARTMENT OF VETERANS AFFAIRS Joint Biomedical Laboratory Research and Development and Clinical Science Research and Development Services Scientific Merit Review Board, Notice of Meeting Amendment The... Development and Clinical Science Research and Development Services Scientific Merit Review Board have changed...

Solar Radiation Research Laboratory | Energy Systems Integration Facility |

Science.gov (United States)

Solar Radiation Research Laboratory (SRRL) has been collecting continuous measurements of basic solar continuous operation. More than 75 instruments contribute to the Baseline Measurement System by recording

How Solar Resource Data supports Research and Development

OpenAIRE

Kern, Jürgen

2013-01-01

The presentation describes the methods of renewable resource data, how the research and development will benefits from Renewable Resource Atlas and how institutions will leverage the solar monitoring station data to support renewable energy project deployment in other locations throughout the Kingdom.

Nuclear physics and heavy element research at Lawrence Livermore National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Stoyer, Mark A; Ahle, L E; Becker, J A; Bernshein, L A; Bleuel, D L; Burke, J T; Dashdorj, D; Henderson, R A; Hurst, A M; Kenneally, Jacqueline M; Lesher, S R; Moody, K J; Nelson, S L; Norman, E B; Pedretti, M; Scielzo, N D; Shaughnessy, D A; Sheets, S A; Stoeffl, W; Stoyer, N J [Lawrence Livermore National Laboratory, University of California, Livermore (United States)

2009-12-31

This paper highlights some of the current basic nuclear physics research at Lawrence Livermore National Laboratory (LLNL). The work at LLNL concentrates on investigating nuclei at the extremes. The Experimental Nuclear Physics Group performs research to improve our understanding of nuclei, nuclear reactions, nuclear decay processes and nuclear astrophysics; an expertise utilized for important laboratory national security programs and for world-class peer-reviewed basic research.

Known structure, unknown function: An inquiry‐based undergraduate biochemistry laboratory course

Science.gov (United States)

Gray, Cynthia; Price, Carol W.; Lee, Christopher T.; Dewald, Alison H.; Cline, Matthew A.; McAnany, Charles E.

2015-01-01

Abstract Undergraduate biochemistry laboratory courses often do not provide students with an authentic research experience, particularly when the express purpose of the laboratory is purely instructional. However, an instructional laboratory course that is inquiry‐ and research‐based could simultaneously impart scientific knowledge and foster a student's research expertise and confidence. We have developed a year‐long undergraduate biochemistry laboratory curriculum wherein students determine, via experiment and computation, the function of a protein of known three‐dimensional structure. The first half of the course is inquiry‐based and modular in design; students learn general biochemical techniques while gaining preparation for research experiments in the second semester. Having learned standard biochemical methods in the first semester, students independently pursue their own (original) research projects in the second semester. This new curriculum has yielded an improvement in student performance and confidence as assessed by various metrics. To disseminate teaching resources to students and instructors alike, a freely accessible Biochemistry Laboratory Education resource is available at http://biochemlab.org. © 2015 The Authors Biochemistry and Molecular Biology Education published by Wiley Periodicals, Inc. on behalf of International Union of Biochemistry and Molecular Biology, 43(4):245–262, 2015. PMID:26148241

Research Opportunities at Storm Peak Laboratory

Science.gov (United States)

Hallar, A. G.; McCubbin, I. B.

2006-12-01

The Desert Research Institute (DRI) operates a high elevation facility, Storm Peak Laboratory (SPL), located on the west summit of Mt. Werner in the Park Range near Steamboat Springs, Colorado at an elevation of 3210 m MSL (Borys and Wetzel, 1997). SPL provides an ideal location for long-term research on the interactions of atmospheric aerosol and gas- phase chemistry with cloud and natural radiation environments. The ridge-top location produces almost daily transition from free tropospheric to boundary layer air which occurs near midday in both summer and winter seasons. Long-term observations at SPL document the role of orographically induced mixing and convection on vertical pollutant transport and dispersion. During winter, SPL is above cloud base 25% of the time, providing a unique capability for studying aerosol-cloud interactions (Borys and Wetzel, 1997). A comprehensive set of continuous aerosol measurements was initiated at SPL in 2002. SPL includes an office-type laboratory room for computer and instrumentation setup with outside air ports and cable access to the roof deck, a cold room for precipitation and cloud rime ice sample handling and ice crystal microphotography, a 150 m2 roof deck area for outside sampling equipment, a full kitchen and two bunk rooms with sleeping space for nine persons. The laboratory is currently well equipped for aerosol and cloud measurements. Particles are sampled from an insulated, 15 cm diameter manifold within approximately 1 m of its horizontal entry point through an outside wall. The 4 m high vertical section outside the building is capped with an inverted can to exclude large particles.

Preliminary research on quantitative methods of water resources carrying capacity based on water resources balance sheet

Science.gov (United States)

Wang, Yanqiu; Huang, Xiaorong; Gao, Linyun; Guo, Biying; Ma, Kai

2018-06-01

Water resources are not only basic natural resources, but also strategic economic resources and ecological control factors. Water resources carrying capacity constrains the sustainable development of regional economy and society. Studies of water resources carrying capacity can provide helpful information about how the socioeconomic system is both supported and restrained by the water resources system. Based on the research of different scholars, major problems in the study of water resources carrying capacity were summarized as follows: the definition of water resources carrying capacity is not yet unified; the methods of carrying capacity quantification based on the definition of inconsistency are poor in operability; the current quantitative research methods of water resources carrying capacity did not fully reflect the principles of sustainable development; it is difficult to quantify the relationship among the water resources, economic society and ecological environment. Therefore, it is necessary to develop a better quantitative evaluation method to determine the regional water resources carrying capacity. This paper proposes a new approach to quantifying water resources carrying capacity (that is, through the compilation of the water resources balance sheet) to get a grasp of the regional water resources depletion and water environmental degradation (as well as regional water resources stock assets and liabilities), figure out the squeeze of socioeconomic activities on the environment, and discuss the quantitative calculation methods and technical route of water resources carrying capacity which are able to embody the substance of sustainable development.

Tensions within an industrial research laboratory: the Philips laboratory's x-ray department between the wars

NARCIS (Netherlands)

Boersma, F.K.

2003-01-01

Tensions arose in the X-ray department of the Philips research laboratory during the interwar period, caused by the interplay among technological development, organizational culture, and individual behavior. This article traces the efforts of Philips researchers to find a balance between their

Mobile robotics research at Sandia National Laboratories

Energy Technology Data Exchange (ETDEWEB)

Morse, W.D.

1998-09-01

Sandia is a National Security Laboratory providing scientific and engineering solutions to meet national needs for both government and industry. As part of this mission, the Intelligent Systems and Robotics Center conducts research and development in robotics and intelligent machine technologies. An overview of Sandia`s mobile robotics research is provided. Recent achievements and future directions in the areas of coordinated mobile manipulation, small smart machines, world modeling, and special application robots are presented.

Research laboratories annual report. 1973 and 1974

International Nuclear Information System (INIS)

1975-02-01

This report presents brief summaries of the research carried out at the Israel A.E.C. laboratories during the two years 1973 and 1974 in the following fields: theoretical physics and chemistry, neutron and reactor physics, solid state physics and metallurgy, laser-induced plasma research, nuclear physics and chemistry, radiation chemistry and applications of radiation and radioisotopes, physical and inorganic chemistry, analytical chemistry, health physics, environmental studies, instrumentation and techniques. (B.G.)

The Horonobe Underground Research Laboratory (Tentative name) Project. A program on survey and research performed from earth surface

International Nuclear Information System (INIS)

2001-03-01

The Horonobe Underground Research Laboratory (Tentative name) Project under planning at Horonobe-machi by the Japan Nuclear Cycle Development Institute (JNC) is a research facility on deep underground shown in the Long-term program on research, development and application of nuclear energy (June, 1994)' (LPNE), where some researches on the deep underground targeted at sedimentary rocks are carried out. The plan on The Horonobe Underground Research Laboratory performed at Horonobe-machi' is an about 20 years plan ranging from beginning to finishing of its survey and research, which is carried out by three steps such as 'Survey and research performed from earth surface', 'Survey and research performed under excavation of road', and Survey and research performed by using the road'. The Horonobe Underground Research Laboratory is one of research facilities on deep underground shown its importance in LPNE, and carries out some researches on the deep underground at a target of the sedimentary rocks. And also The Horonobe Underground Research Laboratory confirms some technical reliability and support on stratum disposal shown in the 'Technical reliability on stratum disposal of the high level radioactive wastes. The Second Progress Report of R and D on geological disposal' summarized on November, 1999 by JNC through actual tests and researches at the deep stratum. The obtained results are intended to reflect to disposal business of The Horonobe Underground Research Laboratory and safety regulation and so on performed by the government, together with results of stratum science research, at the Tono Geoscience Center, of geological disposal R and D at the Tokai Works, or of international collaborations. For R and D at the The Horonobe Underground Research Laboratory after 2000, following subjects are shown: 1) Survey technique on long-term stability of geological environment, 2) Survey technique on geological environment, 3) Engineering technique on engineered barrier and

Emotional Intelligence Research within Human Resource Development Scholarship

Science.gov (United States)

Farnia, Forouzan; Nafukho, Fredrick Muyia

2016-01-01

Purpose: The purpose of this study is to review and synthesize pertinent emotional intelligence (EI) research within the human resource development (HRD) scholarship. Design/methodology/approach: An integrative review of literature was conducted and multiple electronic databases were searched to find the relevant resources. Using the content…

Laboratories new to the ICRM

International Nuclear Information System (INIS)

Karam, Lisa; Anagnostakis, Marios J.; Gudelis, Arunas; Marsoem, Pujadi; Mauring, Alexander; Wurdiyanto, Gatot; Yücel, Ülkü

2012-01-01

The Scientific Committee of the ICRM decided, for the 2011 Conference, to present laboratories that are at a key developmental stage in establishing, expanding or applying radionuclide metrology capabilities. The expansion of radionuclide metrology capabilities is crucial to meet evolving and emerging needs in health care, environmental monitoring, and nuclear energy. Five laboratories (from Greece, Lithuania, Indonesia, Norway and Turkey) agreed to participate. Each laboratory is briefly introduced, and examples of their capabilities and standardization activities are discussed. - Highlights: ► Four laboratories in radionuclide metrology are described. ► Health, environment, and energy applications are motivators. ► Facilities and resources supporting research activities are discussed. ► Activities in primary and secondary standardizations are also discussed.

Laboratory services series: the utilization of scientific glassblowing in a national research and development laboratory

International Nuclear Information System (INIS)

Farnham, R.M.; Poole, R.W.

1976-04-01

Glassblowing services at a national research and development laboratory provide unique equipment tailored for specific research efforts, small-scale process items for flowsheet demonstrations, and solutions for unusual technical problems such as glass-ceramic unions. Facilities, equipment, and personnel necessary for such services are described

Annual report of Nuclear Engineering Research Laboratory, University of Tokyo in fiscal 1989

International Nuclear Information System (INIS)

1990-01-01

This report summerizes the research and educational activities at the Nuclear Engineering Research Laboratory, Faculty of Engineering, University of Tokyo. The Laboratory holds four main facilities, which are Yayoi reactor, an electron accelerator, fusion blanket research facility, and heavy ion irradiation research facility. And they are open to the researchers both inside and outside the University. The application of the facilities are described. The activities and achievements of the Laboratory staffs, and theses for graduate, master, and doctor degrees are also summerized. (J.P.N.)

Bibliography on Biomass Feedstock Research: 1978-2002

Energy Technology Data Exchange (ETDEWEB)

Cushman, J.H.

2003-05-01

This report provides bibliographic citations for more than 1400 reports on biomass feedstock development published by Oak Ridge National Laboratory and its collaborators from 1978 through 2002. Oak Ridge National Laboratory is engaged in analysis of biomass resource supplies, research on the sustainability of feedstock resources, and research on feedstock engineering and infrastructure. From 1978 until 2002, Oak Ridge National Laboratory also provided technical leadership for the U.S. Department of Energy's Bioenergy Feedstock Development Program (BFDP), which supported research to identify and develop promising energy crops. This bibliography lists reports published by Oak Ridge National Laboratory and by its collaborators in the BFDP, including graduate student theses and dissertations.

Promoting Good Clinical Laboratory Practices and Laboratory Accreditation to Support Clinical Trials in Sub-Saharan Africa

Science.gov (United States)

Shott, Joseph P.; Saye, Renion; Diakité, Moussa L.; Sanogo, Sintry; Dembele, Moussa B.; Keita, Sekouba; Nagel, Mary C.; Ellis, Ruth D.; Aebig, Joan A.; Diallo, Dapa A.; Doumbo, Ogobara K.

2012-01-01

Laboratory capacity in the developing world frequently lacks quality management systems (QMS) such as good clinical laboratory practices, proper safety precautions, and adequate facilities; impacting the ability to conduct biomedical research where it is needed most. As the regulatory climate changes globally, higher quality laboratory support is needed to protect study volunteers and to accurately assess biological parameters. The University of Bamako and its partners have undertaken a comprehensive QMS plan to improve quality and productivity using the Clinical and Laboratory Standards Institute standards and guidelines. The clinical laboratory passed the College of American Pathologists inspection in April 2010, and received full accreditation in June 2010. Our efforts to implement high-quality standards have been valuable for evaluating safety and immunogenicity of malaria vaccine candidates in Mali. Other disease-specific research groups in resource-limited settings may benefit by incorporating similar training initiatives, QMS methods, and continual improvement practices to ensure best practices. PMID:22492138

The Cost-Effective Laboratory: Implementation of Economic Evaluation of Laboratory Testing

Directory of Open Access Journals (Sweden)

Bogavac-Stanojevic Natasa

2017-09-01

Full Text Available Laboratory testing as a part of laboratory in vitro diagnostic (IVD has become required tool in clinical practice for diagnosing, monitoring and prognosis of diseases, as well as for prediction of treatment response. The number of IVD tests available in laboratory practice has increased over the past decades and is likely to further increase in the future. Consequently, there is growing concern about the overutilization of laboratory tests and rising costs for laboratory testing. It is estimated that IVD accounts for between 1.4 and 2.3% of total healthcare expenditure and less than 5% of total hospital cost (Lewin Group report. These costs are rather low when compared to pharmaceuticals and medical aids which account for 15 and 5%, respectively. On the other hand, IVD tests play an important role in clinical practice, as they influence from 60% to 70% of clinical decision-making. Unfortunately, constant increases in healthcare spending are not directly related to healthcare benefit. Since healthcare resources are limited, health payers are interested whether the benefits of IVD tests are actually worth their cost. Many articles have introduced frameworks to assess the economic value of IVD tests. The most appropriate tool for quantitative assessment of their economic value is cost-effectiveness (CEA and cost-utility (CUA analysis. The both analysis determine cost in terms of effectiveness or utilities (combine quantity and quality of life of new laboratory test against its alternative. On the other hand, some investigators recommended calculation of laboratory test value as product of two ratios: Laboratory test value = (Technical accuracy/Turnaround time × (Utility/Costs. Recently, some researches used multicriteria decision analysis which allows comparison of diagnostic strategies in terms of benefits, opportunities, costs and risks. All analyses are constructed to identify laboratory test that produce the greatest healthcare benefit with

Progress report from the Studsvik Neutron Research Laboratory 1987-89

International Nuclear Information System (INIS)

Dahlborg, U.; Ebbsjoe, I.; Holmqvist, B.

1993-01-01

The present publication contains information from activities at the Studsvik Neutron Research Laboratory (NFL) and the Department of Neutron Research. NFL is the base for the research activities at the Studvik reactors. It is administrated by the University of Uppsala and is established to facilitate reactor based research. The laboratory is intended to, in co-operation with institutes and departments at universities in Sweden, develop, construct and maintain experimental equipment for this kind of research and to make it available for scientists at Swedish universitites and, if possible, also to scientists outside the universities. The research at the Studsvik facilities has during 1989 been performed by groups from Uppsala University, Royal Institute of Technology in Stockholm, Chalmers Technical University, Gothenburg, and by scientists at NFL. The research program of the groups is divided into three main areas, scattering of thermal neutrons, nuclear chemistry and nuclear physics, and neutron capture radiography. The program for subatomic physics, especially neutron physics, at the Department for Neutron Research, Uppsala University has also staff permanently placed at NFL but they are in their research using the facilities at the The Svedberg Laboratory, Uppsala. In addition to supporting research NFL has also put substantial efforts on creating facilities for training of undergraduate students. Thus a facility for practical exercises in neutron physics, activation analysis and radiography has recently been installed at the R2-0 reactor as a collaboration between NFL, Dept. of Neutron Research, Upppsala and Department for Reactor Physics, KTH

Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: Diagnostic cohort study.

Directory of Open Access Journals (Sweden)

Kate Birnie

Full Text Available To compare the validity of diagnosis of urinary tract infection (UTI through urine culture between samples processed in routine health service laboratories and those processed in a research laboratory.We conducted a prospective diagnostic cohort study in 4808 acutely ill children aged <5 years attending UK primary health care. UTI, defined as pure/predominant growth ≥105 CFU/mL of a uropathogen (the reference standard, was diagnosed at routine health service laboratories and a central research laboratory by culture of urine samples. We calculated areas under the receiver-operator curve (AUC for UTI predicted by pre-specified symptoms, signs and dipstick test results (the "index test", separately according to whether samples were obtained by clean catch or nappy (diaper pads.251 (5.2% and 88 (1.8% children were classified as UTI positive by health service and research laboratories respectively. Agreement between laboratories was moderate (kappa = 0.36; 95% confidence interval [CI] 0.29, 0.43, and better for clean catch (0.54; 0.45, 0.63 than nappy pad samples (0.20; 0.12, 0.28. In clean catch samples, the AUC was lower for health service laboratories (AUC = 0.75; 95% CI 0.69, 0.80 than the research laboratory (0.86; 0.79, 0.92. Values of AUC were lower in nappy pad samples (0.65 [0.61, 0.70] and 0.79 [0.70, 0.88] for health service and research laboratory positivity, respectively than clean catch samples.The agreement of microbiological diagnosis of UTI comparing routine health service laboratories with a research laboratory was moderate for clean catch samples and poor for nappy pad samples and reliability is lower for nappy pad than for clean catch samples. Positive results from the research laboratory appear more likely to reflect real UTIs than those from routine health service laboratories, many of which (particularly from nappy pad samples could be due to contamination. Health service laboratories should consider adopting procedures used

Comparison of microbiological diagnosis of urinary tract infection in young children by routine health service laboratories and a research laboratory: Diagnostic cohort study

Science.gov (United States)

Birnie, Kate; Hay, Alastair D.; Wootton, Mandy; Howe, Robin; MacGowan, Alasdair; Whiting, Penny; Lawton, Michael; Delaney, Brendan; Downing, Harriet; Dudley, Jan; Hollingworth, William; Lisles, Catherine; Little, Paul; O’Brien, Kathryn; Pickles, Timothy; Rumsby, Kate; Thomas-Jones, Emma; Van der Voort, Judith; Waldron, Cherry-Ann; Harman, Kim; Hood, Kerenza; Butler, Christopher C.; Sterne, Jonathan A. C.

2017-01-01

Objectives To compare the validity of diagnosis of urinary tract infection (UTI) through urine culture between samples processed in routine health service laboratories and those processed in a research laboratory. Population and methods We conducted a prospective diagnostic cohort study in 4808 acutely ill children aged <5 years attending UK primary health care. UTI, defined as pure/predominant growth ≥105 CFU/mL of a uropathogen (the reference standard), was diagnosed at routine health service laboratories and a central research laboratory by culture of urine samples. We calculated areas under the receiver-operator curve (AUC) for UTI predicted by pre-specified symptoms, signs and dipstick test results (the “index test”), separately according to whether samples were obtained by clean catch or nappy (diaper) pads. Results 251 (5.2%) and 88 (1.8%) children were classified as UTI positive by health service and research laboratories respectively. Agreement between laboratories was moderate (kappa = 0.36; 95% confidence interval [CI] 0.29, 0.43), and better for clean catch (0.54; 0.45, 0.63) than nappy pad samples (0.20; 0.12, 0.28). In clean catch samples, the AUC was lower for health service laboratories (AUC = 0.75; 95% CI 0.69, 0.80) than the research laboratory (0.86; 0.79, 0.92). Values of AUC were lower in nappy pad samples (0.65 [0.61, 0.70] and 0.79 [0.70, 0.88] for health service and research laboratory positivity, respectively) than clean catch samples. Conclusions The agreement of microbiological diagnosis of UTI comparing routine health service laboratories with a research laboratory was moderate for clean catch samples and poor for nappy pad samples and reliability is lower for nappy pad than for clean catch samples. Positive results from the research laboratory appear more likely to reflect real UTIs than those from routine health service laboratories, many of which (particularly from nappy pad samples) could be due to contamination. Health service

Fair Resource Allocation to Health Research: Priority Topics for Bioethics Scholarship.

Science.gov (United States)

Pratt, Bridget; Hyder, Adnan A

2017-07-01

This article draws attention to the limited amount of scholarship on what constitutes fairness and equity in resource allocation to health research by individual funders. It identifies three key decisions of ethical significance about resource allocation that research funders make regularly and calls for prioritizing scholarship on those topics - namely, how health resources should be fairly apportioned amongst public health and health care delivery versus health research, how health research resources should be fairly allocated between health problems experienced domestically versus other health problems typically experienced by disadvantaged populations outside the funder's country, and how domestic and non-domestic health research funding should be further apportioned to different areas, e.g. types of research and recipients. These three topics should be priorities for bioethics research because their outcomes have a substantial bearing on the achievement of health justice. The proposed agenda aims to move discussion on the ethics of health research funding beyond its current focus on the mismatch between worldwide basic and clinical research investment and the global burden of disease. Individual funders' decision-making on whether and to what extent to allocate resources to non-domestic health research, health systems research, research on the social determinants of health, capacity development, and recipients in certain countries should also be the focus of ethical scrutiny. © 2017 John Wiley & Sons Ltd.

Adverse reproduction outcomes among employees working in biomedical research laboratories

DEFF Research Database (Denmark)

Wennborg, H.; Bonde, Jens Peter; Stenbeck, M.

2002-01-01

Objectives The aim of the study was to investigate reproductive outcomes such as birthweight, preterm births, and postterm births among women working in research laboratories while pregnant. Methods Female university personnel were identified from a source cohort of Swedish laboratory employees...

Infrastructure resources for clinical research in amyotrophic lateral sclerosis.

Science.gov (United States)

Sherman, Alexander V; Gubitz, Amelie K; Al-Chalabi, Ammar; Bedlack, Richard; Berry, James; Conwit, Robin; Harris, Brent T; Horton, D Kevin; Kaufmann, Petra; Leitner, Melanie L; Miller, Robert; Shefner, Jeremy; Vonsattel, Jean Paul; Mitsumoto, Hiroshi

2013-05-01

Clinical trial networks, shared clinical databases, and human biospecimen repositories are examples of infrastructure resources aimed at enhancing and expediting clinical and/or patient oriented research to uncover the etiology and pathogenesis of amyotrophic lateral sclerosis (ALS), a rapidly progressive neurodegenerative disease that leads to the paralysis of voluntary muscles. The current status of such infrastructure resources, as well as opportunities and impediments, were discussed at the second Tarrytown ALS meeting held in September 2011. The discussion focused on resources developed and maintained by ALS clinics and centers in North America and Europe, various clinical trial networks, U.S. government federal agencies including the National Institutes of Health (NIH), the Agency for Toxic Substances and Disease Registry (ATSDR) and the Centers for Disease Control and Prevention (CDC), and several voluntary disease organizations that support ALS research activities. Key recommendations included 1) the establishment of shared databases among individual ALS clinics to enhance the coordination of resources and data analyses; 2) the expansion of quality-controlled human biospecimen banks; and 3) the adoption of uniform data standards, such as the recently developed Common Data Elements (CDEs) for ALS clinical research. The value of clinical trial networks such as the Northeast ALS (NEALS) Consortium and the Western ALS (WALS) Consortium was recognized, and strategies to further enhance and complement these networks and their research resources were discussed.

The waste management at research laboratories - problems and solutions

International Nuclear Information System (INIS)

Dellamano, Jose Claudio; Vicente, Roberto

2011-01-01

The radioactive management in radioactive installations must be planned and controlled. However, in the case of research laboratories, that management is compromised due to the common use of materials and installations, the lack of trained personnel and the nonexistence of clear and objective orientations by the regulator organism. Such failures cause an increasing of generated radioactive wastes and the imprecision or nonexistence of record of radioactive substances, occasioning a financial wastage, and the cancelling of licences for use of radioactive substances. This paper discusses and proposes solutions for the problems found at radioactive waste management in research laboratories

Environmental survey at the Lucas Heights Research Laboratories. 1983

International Nuclear Information System (INIS)

Giles, M.S.; Dudaitis, A.

1985-12-01

Results are presented of the environmental survey conducted in the neighbourhood of the Lucas Heights Research Laboratories during 1983. These results are satisfactory. No radioactivity which could have originated from these laboratories was found in samples collected from possible human food chains. All low-level liquid and gaseous waste discharges were within authorised limits. The maximum possible annual dose to the general public from airborne waste discharges during this period is estimated to be less than 0.01 millisieverts, which is 1 per cent of the limit for long-term exposure that is recommended by the National Health and Medical Research Council

Pacific Northwest Laboratory annual report for 1984 to the DOE Office of Energy Research. Part 3. Atmospheric sciences

International Nuclear Information System (INIS)

Elderkin, C.E.

1985-02-01

The goals of atmospheric research at Pacific Northwest Laboratory (PNL) are to assess, describe, and predict the nature and fate of atmospheric contaminants and to study the impacts of contaminants on local, regional, and global climates. The contaminants being investigated are those resulting from the development and use of conventional resources (coal, gas, oil, and nuclear power) as well as alternative energy sources. The description of the research is organized into 3 sections: (1) Atmospheric Studies in Complex Terrain (ASCOT); (2) Boundary Layer Meteorology; and (3) Dispersion, Deposition, and Resuspension of Atmospheric Contaminants. Separate analytics have been done for each of the sections and are indexed and contained in the EDB

Progress report from the Studsvik Neutron Research Laboratory 1990-91

International Nuclear Information System (INIS)

Dahlborg, U.; Ebbsjoe, I.; Holmqvist, B.

1992-01-01

The Studsvik Neutron Research Laboratory (NFL) is the base for the research activities at the Studsvik reactors. It is administrated by the University of Uppsala and is established to facilitate reactor based research. The laboratory is intended to, in co-operation with institutes and department at universities in Sweden, develop, construct and maintain experimental equipment for this kind of research and to make it available for scientists at Swedish universities and, if possible, also to scientists outside the universities. The research at the Studsvik facilities has during 1990 and 1991 been performed by groups form Uppsala University, Royal Institute of Technology, Stockholm, Chalmers Technical University, Gothenburg, and by scientists at NFL. The research programme of the groups is divided into three main areas, scattering of thermal neutrons, nuclear chemistry/nuclear physics, and neutron capture radiography

Idaho National Laboratory Cultural Resource Monitoring Report for Fiscal Year 2016

International Nuclear Information System (INIS)

Gilbert, Hollie Kae; Holmer, Marie Pilkington; Olson, Christina Liegh; Pace, Brenda Ringe

2016-01-01

This report describes the cultural resource monitoring activities of the Idaho National Laboratory's (INL) Cultural Resource Management (CRM) Office during fiscal year (FY) 2016. Overall monitoring included surveillance of the following 23 individual cultural resource localities: two locations with human remains, one of which is also a cave; seven additional caves; six prehistoric archaeological sites; four historic archaeological sites; one historic trail; Experimental Breeder Reactor I (EBR-I), a National Historic Landmark; Aircraft Nuclear Propulsion (ANP) objects located at EBR-I; and one Arco Naval Proving Ground (NPG) property, CF-633 and related objects and structures. Several INL work processes and projects were also monitored to confirm compliance with original INL CRM recommendations and assess the effects of ongoing work. On one occasion, ground disturbing activities within the boundaries of the Critical Infrastructure Test Range Complex (CITRC) were observed by INL CRM staff prepared to respond to any additional finds of Native American human remains. Additionally, the CRM office was notified during two Trespass Investigations conducted by INL Security. Most of the cultural resources monitored in FY 2016 exhibited no adverse impacts, resulting in Type 1 impact assessments. However, Type 2 impacts were noted five times. Three previously reported Type 2 impacts were once again documented at the EBR-I National Historic Landmark, including spalling and deterioration of bricks due to inadequate drainage, minimal maintenance, and rodent infestation. The ANP engines and locomotive on display at the EBR-I Visitors Center also exhibited impacts related to long term exposure. Finally, most of the Arco NPG properties monitored at Central Facilities Area exhibited problems with lack of timely and appropriate maintenance as well as inadequate drainage. No new Type 3 or Type 4 impacts that adversely affected significant cultural resources and threatened National

10 best resources on ... mixed methods research in health systems.

Science.gov (United States)

Ozawa, Sachiko; Pongpirul, Krit

2014-05-01

Mixed methods research has become increasingly popular in health systems. Qualitative approaches are often used to explain quantitative results and help to develop interventions or survey instruments. Mixed methods research is especially important in low- and middle-income country (LMIC) settings, where understanding social, economic and cultural contexts are essential to assess health systems performance. To provide researchers and programme managers with a guide to mixed methods research in health systems, we review the best resources with a focus on LMICs. We selected 10 best resources (eight peer-reviewed articles and two textbooks) based on their importance and frequency of use (number of citations), comprehensiveness of content, usefulness to readers and relevance to health systems research in resource-limited contexts. We start with an overview on mixed methods research and discuss resources that are useful for a better understanding of the design and conduct of mixed methods research. To illustrate its practical applications, we provide examples from various countries (China, Vietnam, Kenya, Tanzania, Zambia and India) across different health topics (tuberculosis, malaria, HIV testing and healthcare costs). We conclude with some toolkits which suggest what to do when mixed methods findings conflict and provide guidelines for evaluating the quality of mixed methods research.

USGS research on energy resources, 1986; program and abstracts

Science.gov (United States)

Carter, Lorna M.H.

1986-01-01

The extended abstracts in this volume are summaries of the papers presented orally and as posters in the second V. E. McKelvey Forum on Mineral and Energy Resources, entitled "USGS Research on Energy Resources-1986." The Forum has been established to improve communication between the USGS and the earth science community by presenting the results of current USGS research on nonrenewable resources in a timely fashion and by providing an opportunity for individuals from other organizations to meet informally with USGS scientists and managers. It is our hope that the McKelvey Forum will help to make USGS programs more responsive to the needs of the earth science community, particularly the mining and petroleum industries, and Win foster closer cooperation between organizations and individuals. The Forum was named after former Director Vincent E. McKelvey in recognition of his lifelong contributions to research, development, and administration in mineral and energy resources, as a scientist, as Chief Geologist, and as Director of the U.S. Geological Survey. The Forum will be an annual event, and its subject matter will alternate between mineral and energy resources. We expect that the format will change somewhat from year to year as various approaches are tried, but its primary purpose will remain the same: to encourage direct communication between USGS scientists and the representatives of other earth-science related organizations. Energy programs of the USGS include oil and gas, coal, geothermal, uranium-thorium, and oil shale; work in these programs spans the national domain, including surveys of the offshore Exclusive Economic Zone. The topics selected for presentation at this McKelvey Forum represent an overview of the scientific breadth of USGS research on energy resources. They include aspects of petroleum occurrence in Eastern United States rift basins, the origin of magnetic anomalies over oil fields, accreted terranes and energy-resource implications, coal

Laboratory directed research and development FY98 annual report; TOPICAL

International Nuclear Information System (INIS)

Al-Ayat, R; Holzrichter, J

1999-01-01

In 1984, Congress and the Department of Energy (DOE) established the Laboratory Directed Research and Development (LDRD) Program to enable the director of a national laboratory to foster and expedite innovative research and development (R and D) in mission areas. The Lawrence Livermore National Laboratory (LLNL) continually examines these mission areas through strategic planning and shapes the LDRD Program to meet its long-term vision. The goal of the LDRD Program is to spur development of new scientific and technical capabilities that enable LLNL to respond to the challenges within its evolving mission areas. In addition, the LDRD Program provides LLNL with the flexibility to nurture and enrich essential scientific and technical competencies and enables the Laboratory to attract the most qualified scientists and engineers. The FY98 LDRD portfolio described in this annual report has been carefully structured to continue the tradition of vigorously supporting DOE and LLNL strategic vision and evolving mission areas. The projects selected for LDRD funding undergo stringent review and selection processes, which emphasize strategic relevance and require technical peer reviews of proposals by external and internal experts. These FY98 projects emphasize the Laboratory's national security needs: stewardship of the U.S. nuclear weapons stockpile, responsibility for the counter- and nonproliferation of weapons of mass destruction, development of high-performance computing, and support of DOE environmental research and waste management programs

Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories.

Science.gov (United States)

Homer, Lesley C; Alderman, T Scott; Blair, Heather Ann; Brocard, Anne-Sophie; Broussard, Elaine E; Ellis, Robert P; Frerotte, Jay; Low, Eleanor W; McCarthy, Travis R; McCormick, Jessica M; Newton, JeT'Aime M; Rogers, Francine C; Schlimgen, Ryan; Stabenow, Jennifer M; Stedman, Diann; Warfield, Cheryl; Ntiforo, Corrie A; Whetstone, Carol T; Zimmerman, Domenica; Barkley, Emmett

2013-03-01

The Guidelines for Biosafety Training Programs for Workers Assigned to BSL-3 Research Laboratories were developed by biosafety professionals who oversee training programs for the 2 national biocontainment laboratories (NBLs) and the 13 regional biocontainment laboratories (RBLs) that participate in the National Institute of Allergy and Infectious Diseases (NIAID) NBL/RBL Network. These guidelines provide a general training framework for biosafety level 3 (BSL-3) high-containment laboratories, identify key training concepts, and outline training methodologies designed to standardize base knowledge, understanding, and technical competence of laboratory personnel working in high-containment laboratories. Emphasis is placed on building a culture of risk assessment-based safety through competency training designed to enhance understanding and recognition of potential biological hazards as well as methods for controlling these hazards. These guidelines may be of value to other institutions and academic research laboratories that are developing biosafety training programs for BSL-3 research.

Monitoring system of the Tritium Research Laboratory, Sandia Laboratories, Livermore, CA

International Nuclear Information System (INIS)

Wall, W.R.; Hafner, R.S.; Westfall, D.L.; Ristau, R.D.

1978-11-01

Automated tritium monitoring is now in use at the Tritium Research Laboratory (TRL). Betatec 100 tritium monitors, along with several Sandia-designed accessories, have been combined with a PDP 11/40 computer to automatically read and record tritium concentrations of room air, containment, and cleanup systems. Each individual monitoring system, in addition to a local display in the area of interest, has a visible/audible display in the control room. Each system is then channeled into the PDP 11/40 computer, providing immediate assessment of the status of the entire laboratory from a central location. Measurement capability ranges from μCi/m 3 levels for room air monitoring to kCi/m 3 levels for glove box and cleanup systems monitoring. In this report the overall monitoring system and its capabilities are discussed, with detailed descriptions given of monitors and their components

Cultural Resource Investigations for a Multipurpose Haul Road on the Idaho National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Brenda R. Pace; Cameron Brizzee; Hollie Gilbert; Clayton Marler; Julie Braun Williams

2010-08-01

The U. S. Department of Energy, Idaho Operations Office is considering options for construction of a multipurpose haul road to transport materials and wastes between the Materials and Fuels Complex (MFC) and other Idaho National Laboratory (INL) Site facilities. The proposed road will be closed to the public and designed for limited year-round use. Two primary options are under consideration: a new route south of the existing T-25 power line road and an upgrade to road T-24. In the Spring of 2010, archaeological field surveys and initial coordination and field reconnaissance with representatives from the Shoshone-Bannock Tribes were completed to identify any resources that may be adversely affected by the proposed road construction and to develop recommendations to protect any listed or eligible for listing on the National Register of Historic Places. The investigations showed that 24 archaeological resources and one historic marker are located in the area of potential effects for road construction and operation south of the T-25 powerline road and 27archaeological resources are located in the area of potential effects for road construction and operation along road T-24. Generalized tribal concerns regarding protection of natural resources were also documented in both road corridors. This report outlines recommendations for additional investigations and protective measures that can be implemented to minimize adverse impacts to the identified resources.

Space Station life science research facility - The vivarium/laboratory

Science.gov (United States)

Hilchey, J. D.; Arno, R. D.

1985-01-01

Research opportunities possible with the Space Station are discussed. The objective of the research program will be study gravity relationships for animal and plant species. The equipment necessary for space experiments including vivarium facilities are described. The cost of the development of research facilities such as the vivarium/laboratory and a bioresearch centrifuge is examined.

The WHO/PEPFAR collaboration to prepare an operations manual for HIV prevention, care, and treatment at primary health centers in high-prevalence, resource-constrained settings: defining laboratory services.

Science.gov (United States)

Spira, Thomas; Lindegren, Mary Lou; Ferris, Robert; Habiyambere, Vincent; Ellerbrock, Tedd

2009-06-01

The expansion of HIV/AIDS care and treatment in resource-constrained countries, especially in sub-Saharan Africa, has generally developed in a top-down manner. Further expansion will involve primary health centers where human and other resources are limited. This article describes the World Health Organization/President's Emergency Plan for AIDS Relief collaboration formed to help scale up HIV services in primary health centers in high-prevalence, resource-constrained settings. It reviews the contents of the Operations Manual developed, with emphasis on the Laboratory Services chapter, which discusses essential laboratory services, both at the center and the district hospital level, laboratory safety, laboratory testing, specimen transport, how to set up a laboratory, human resources, equipment maintenance, training materials, and references. The chapter provides specific information on essential tests and generic job aids for them. It also includes annexes containing a list of laboratory supplies for the health center and sample forms.

Pacific Northwest Laboratory: Director`s overview of research performed for DOE Office of Health And Environmental Research

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-06-01

A significant portion of the research undertaken at Pacific Northwest Laboratory (PNL) is focused on the strategic programs of the US Department of Energy`s (DOE) Office of Health and Environmental Research (OHER). These programs, which include Environmental Processes (Subsurface Science, Ecosystem Function and Response, and Atmospheric Chemistry), Global Change (Climate Change, Environmental Vulnerability, and Integrated Assessments), Biotechnology (Human Genome and Structural Biology), and Health (Health Effects and Medical Applications), have been established by OHER to support DOE business areas in science and technology and environmental quality. PNL uses a set of critical capabilities based on the Laboratory`s research facilities and the scientific and technological expertise of its staff to help OHER achieve its programmatic research goals. Integration of these capabilities across the Laboratory enables PNL to assemble multidisciplinary research teams that are highly effective in addressing the complex scientific and technical issues associated with OHER-sponsored research. PNL research efforts increasingly are focused on complex environmental and health problems that require multidisciplinary teams to address the multitude of time and spatial scales found in health and environmental research. PNL is currently engaged in research in the following areas for these OHER Divisions: Environmental Sciences -- atmospheric radiation monitoring, climate modeling, carbon cycle, atmospheric chemistry, ecological research, subsurface sciences, bioremediation, and environmental molecular sciences; Health Effects and Life Sciences -- cell/molecular biology, and biotechnology; Medical Applications and Biophysical Research -- analytical technology, and radiological and chemical physics. PNL`s contributions to OHER strategic research programs are described in this report.

Eighteenth annual risk reduction engineering laboratory research symposium

International Nuclear Information System (INIS)

Anon.

1992-01-01

The Eighteenth Annual Risk Reduction Engineering Laboratory Research Symposium was held in Cincinnati, Ohio, April 14-16, 1992. The purpose of this Symposium was to present the latest significant research findings from ongoing and recently completed projects funded by the Risk Reduction Engineering Laboratory (RREL). These Proceedings are organized into two sections. Sessions A and B, which contain extended abstracts of the paper presentations. A list of poster displays is also included. Subjects include remedial action, treatment, and control technologies for waste disposal, landfill liner and cover systems, underground storage tanks, and demonstration and development of innovative/alternative treatment technologies for hazardous waste. Alternative technology subjects include thermal destruction of hazardous wastes, field evaluations, existing treatment options, emerging treatment processes, waste minimization, and biosystems for hazardous waste destruction

Mouse Model Resources for Vision Research

Directory of Open Access Journals (Sweden)

Jungyeon Won

2011-01-01

Full Text Available The need for mouse models, with their well-developed genetics and similarity to human physiology and anatomy, is clear and their central role in furthering our understanding of human disease is readily apparent in the literature. Mice carrying mutations that alter developmental pathways or cellular function provide model systems for analyzing defects in comparable human disorders and for testing therapeutic strategies. Mutant mice also provide reproducible, experimental systems for elucidating pathways of normal development and function. Two programs, the Eye Mutant Resource and the Translational Vision Research Models, focused on providing such models to the vision research community are described herein. Over 100 mutant lines from the Eye Mutant Resource and 60 mutant lines from the Translational Vision Research Models have been developed. The ocular diseases of the mutant lines include a wide range of phenotypes, including cataracts, retinal dysplasia and degeneration, and abnormal blood vessel formation. The mutations in disease genes have been mapped and in some cases identified by direct sequencing. Here, we report 3 novel alleles of Crxtvrm65, Rp1tvrm64, and Rpe65tvrm148 as successful examples of the TVRM program, that closely resemble previously reported knockout models.

Annual progress report, 1 January 1975--31 December 1975. [Information center on laboratory animals

Energy Technology Data Exchange (ETDEWEB)

1975-01-01

The Institute of Laboratory Animal Resources (ILAR) was founded in 1952 under the auspices of the National Academy of Sciences-National Research Council (NAS-NRC). Located within the Division of Biological Sciences, Assembly of Life Sciences, ILAR serves as a coordinating agency to disseminate information, survey existing and required resources, establish standards and guidelines, promote education, hold conferences, and, generally, upgrade laboratory animal resources within the United States. Activities during 1976 are reported.

Global Impact | Frederick National Laboratory for Cancer Research

Science.gov (United States)

Through its direct support of clinical research, Frederick National Laboratory activities are not limited to national programs. The labis actively involved in more than 400 domestic and international studies related to cancer; influenza, HIV, E

Development of a Research-Oriented Inorganic Chemistry Laboratory Course

Science.gov (United States)

Vallarino, L. M.; Polo, D. L.; Esperdy, K.

2001-02-01

We report the development of a research-oriented, senior-level laboratory course in inorganic chemistry, which is a requirement for chemistry majors who plan to receive the ACS-approved Bachelor of Science degree and is a recommended elective for other chemistry majors. The objective of this course is to give all students the advantage of a research experience in which questions stemming from the literature lead to the formulation of hypotheses, and answers are sought through experiment. The one-semester Inorganic Chemistry Laboratory is ideal for this purpose, since for most students it represents the last laboratory experience before graduation and can assume the role of "capstone" course--a course where students are challenged to recall previously learned concepts and skills and put them into practice in the performance of an individual, original research project. The medium chosen for this teaching approach is coordination chemistry, a branch of chemistry that involves the interaction of inorganic and organic compounds and requires the use of various synthetic and analytical methods. This paper presents an outline of the course organization and requirements, examples of activities performed by the students, and a critical evaluation of the first five years' experience.

Laboratory Directed Research and Development Program. FY 1993

Energy Technology Data Exchange (ETDEWEB)

1994-02-01

This report is compiled from annual reports submitted by principal investigators following the close of fiscal year 1993. This report describes the projects supported and summarizes their accomplishments. The program advances the Laboratory`s core competencies, foundations, scientific capability, and permits exploration of exciting new opportunities. Reports are given from the following divisions: Accelerator and Fusion Research, Chemical Sciences, Earth Sciences, Energy and Environment, Engineering, Environment -- Health and Safety, Information and Computing Sciences, Life Sciences, Materials Sciences, Nuclear Science, Physics, and Structural Biology. (GHH)

Laboratory Directed Research and Development Program Assessment for FY 2014

Energy Technology Data Exchange (ETDEWEB)

Hatton, D. [Brookhaven National Lab. (BNL), Upton, NY (United States)

2014-03-01

Each year, Brookhaven National Laboratory (BNL) is required to provide a program description and overview of its Laboratory Directed Research and Development Program (LDRD) to the Department of Energy in accordance with DOE Order 413.2B dated April 19, 2006. This report fulfills that requirement.

The monitoring system of the Tritium Research Laboratory, Sandia Laboratories, Livermore, California

International Nuclear Information System (INIS)

Hafner, R.S.; Westfall, D.L.; Ristau, R.D.

1978-01-01

Computerized tritium monitoring is now in use at the Tritium Research Laboratory (TRL). Betatec 100 tritium monitors, along with several Sandia designed accessories, have been combined with a PDP 11/40 computer to provide maximum personnel and environmental protection. Each individual monitoring system, in addition to a local display in the area of interest, has a visual/audible display in the control room. Each system is then channeled into the PDP 11/40 computer, providing immediate assessment of the status of the entire laboratory from a central location. Measurement capability ranges from uCi/m 3 levels for room air monitoring to KCi/m 3 levels for glove box and process system monitoring. The overall monitoring system and its capabilities will be presented

The Los Alamos Scientific Laboratory - An Isolated Nuclear Research Establishment

Energy Technology Data Exchange (ETDEWEB)

Bradbury, Norris E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Meade, Roger Allen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2016-09-23

Early in his twenty-five year career as the Director of the Los Alamos Scientific Laboratory, Norris Bradbury wrote at length about the atomic bomb and the many implications the bomb might have on the world. His themes were both technical and philosophical. In 1963, after nearly twenty years of leading the nation’s first nuclear weapons laboratory, Bradbury took the opportunity to broaden his writing. In a paper delivered to the International Atomic Energy Agency’s symposium on the “Criteria in the Selection of Sites for the Construction of Reactors and Nuclear Research Centers,” Bradbury took the opportunity to talk about the business of nuclear research and the human component of operating a scientific laboratory. This report is the transcript of his talk.

2015 Fermilab Laboratory Directed Research & Development Annual Report

Energy Technology Data Exchange (ETDEWEB)

Wester, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

2016-05-26

The Fermi National Accelerator Laboratory (FNAL) is conducting a Laboratory Directed Research and Development (LDRD) program. Fiscal year 2015 represents the first full year of LDRD at Fermilab and includes seven projects approved mid-year in FY14 and six projects approved in FY15. One of the seven original projects has been completed just after the beginning of FY15. The implementation of LDRD at Fermilab is captured in the approved Fermilab 2015 LDRD Annual Program Plan. In FY15, the LDRD program represents 0.64% of Laboratory funding. The scope of the LDRD program at Fermilab will be established over the next couple of years where a portfolio of about 20 on-going projects representing approximately between 1% and 1.5% of the Laboratory funding is anticipated. This Annual Report focuses on the status of the current projects and provides an overview of the current status of LDRD at Fermilab.

Smart Electronic Laboratory Notebooks for the NIST Research Environment.

Science.gov (United States)

Gates, Richard S; McLean, Mark J; Osborn, William A

2015-01-01

Laboratory notebooks have been a staple of scientific research for centuries for organizing and documenting ideas and experiments. Modern laboratories are increasingly reliant on electronic data collection and analysis, so it seems inevitable that the digital revolution should come to the ordinary laboratory notebook. The most important aspect of this transition is to make the shift as comfortable and intuitive as possible, so that the creative process that is the hallmark of scientific investigation and engineering achievement is maintained, and ideally enhanced. The smart electronic laboratory notebooks described in this paper represent a paradigm shift from the old pen and paper style notebooks and provide a host of powerful operational and documentation capabilities in an intuitive format that is available anywhere at any time.

Resource-efficient supply chains: a research framework, literature review and research agenda

NARCIS (Netherlands)

Matopoulos, A.; Barros, A.C.; Vorst, van der J.G.A.J.

2015-01-01

Purpose – The study aims to define a research agenda for creating resource-efficient supply chains (RESCs) by identifying and analysing their key characteristics as well as future research opportunities. Design/methodology/approach – We follow a systematic review method to analyse the literature and

Material Transfer Agreement (MTA) | Frederick National Laboratory for Cancer Research

Science.gov (United States)

Material Transfer Agreements are appropriate for exchange of materials into or out of the Frederick National Laboratory for research or testing purposes, with no collaborative research by parties involving the materials.

Construction and operation of the Howard T. Ricketts Laboratory.

Energy Technology Data Exchange (ETDEWEB)

Van Lonkhuyzen, R.; Stull, L.; Butler, J.; Chang, Y.; Allison, T.; O' Rourke, D.

2006-01-01

The National Institutes of Health (NIH) has proposed to partially fund the construction of the Howard T. Ricketts (HTR) regional biocontainment laboratory (RBL) by the University of Chicago at the U.S. Department of Energy's (DOE's) Argonne National Laboratory in Argonne, Illinois. The HTR Laboratory (HTRL) would be constructed, owned, and operated by the University of Chicago on land leased to it by DOE. The preferred project site is located north of Eastwood Drive and west of Outer Circle Road and is near the biological sciences building. This environmental assessment addresses the potential environmental effects resulting from construction and operation of the proposed facility. The proposed project involves the construction of a research facility with a footprint up to approximately 44,000 ft{sup 2} (4,088 m{sup 2}). The proposed building would house research laboratories, including Biosafety Level 2 and 3 biocontainment space, animal research facilities, administrative offices, and building support areas. The NIH has identified a need for new facilities to support research on potential bioterrorism agents and emerging and re-emerging infectious diseases, to protect the nation from such threats to public health. This research requires specialized laboratory facilities that are designed, managed, and operated to protect laboratory workers and the surrounding community from accidental exposure to agents. The proposed HTRL would provide needed biocontainment space to researchers and promote the advancement of knowledge in the disciplines of biodefense and emerging and re-emerging infectious diseases. Several alternatives were considered for the location of the proposed facility, as well as a no action alternative. The preferred alternative includes the construction of a research facility, up to 44,000 ft{sup 2} (4,088 m{sup 2}), at Argonne National Laboratory, a secure government location. Potential impacts to natural and cultural resources have been

Radioisotope research and development at Los Alamos National Laboratory

International Nuclear Information System (INIS)

Peterson, E.J.

1993-01-01

Throughout its fifty year history, Los Alamos National Laboratory has conducted research and development in the production, isolation, purification, and application of radioactive isotopes. Initially this work supported the weapons development mission of the Laboratory. Over the years the work has evolved to support basic and applied research in many diverse fields, including nuclear medicine, biomedical studies, materials science, environmental research and the physical sciences. In the early 1970s people in the Medical Radioisotope Research Program began irradiating targets at the Los Alamos Meson Physics Facility (LAMPF) to investigate the production and recovery of medically important radioisotopes. Since then spallation production using the high intensity beam at LAMPF has become a significant source of many important radioisotopes. Los Alamos posesses other facilities with isotope production capabilities. Examples are the Omega West Reactor (OWR) and the Van de Graaf Ion Beam Facility (IBF). Historically these facilities have had limited availability for radioisotope production, but recent developments portend a significant radioisotope production mission in the future

Argonne National Laboratory Annual Report of Laboratory Directed Research and Development program activities FY 2011.

Energy Technology Data Exchange (ETDEWEB)

(Office of The Director)

2012-04-25

As a national laboratory Argonne concentrates on scientific and technological challenges that can only be addressed through a sustained, interdisciplinary focus at a national scale. Argonne's eight major initiatives, as enumerated in its strategic plan, are Hard X-ray Sciences, Leadership Computing, Materials and Molecular Design and Discovery, Energy Storage, Alternative Energy and Efficiency, Nuclear Energy, Biological and Environmental Systems, and National Security. The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel technical concepts, enhance the Laboratory's research and development (R and D) capabilities, and pursue its strategic goals. projects are selected from proposals for creative and innovative R and D studies that require advance exploration before they are considered to be sufficiently developed to obtain support through normal programmatic channels. Among the aims of the projects supported by the LDRD Program are the following: establishment of engineering proof of principle, assessment of design feasibility for prospective facilities, development of instrumentation or computational methods or systems, and discoveries in fundamental science and exploratory development.

Argonne National Laboratory Annual Report of Laboratory Directed Research and Development program activities FY 2010.

Energy Technology Data Exchange (ETDEWEB)

(Office of The Director)

2012-04-25

As a national laboratory Argonne concentrates on scientific and technological challenges that can only be addressed through a sustained, interdisciplinary focus at a national scale. Argonne's eight major initiatives, as enumerated in its strategic plan, are Hard X-ray Sciences, Leadership Computing, Materials and Molecular Design and Discovery, Energy Storage, Alternative Energy and Efficiency, Nuclear Energy, Biological and Environmental Systems, and National Security. The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel technical concepts, enhance the Laboratory's research and development (R and D) capabilities, and pursue its strategic goals. projects are selected from proposals for creative and innovative R and D studies that require advance exploration before they are considered to be sufficiently developed to obtain support through normal programmatic channels. Among the aims of the projects supported by the LDRD Program are the following: establishment of engineering proof of principle, assessment of design feasibility for prospective facilities, development of instrumentation or computational methods or systems, and discoveries in fundamental science and exploratory development.

Radiotracer laboratory for agricultural research at the Malaysian Nuclear Agency

International Nuclear Information System (INIS)

Nashriyah Mat; Misman Sumin; Maizatul Akmam Mhd Nasir

2007-01-01

Radiotracer Laboratory for agricultural research at the Malaysian Nuclear Agency was established since 1990. It accommodates three laboratories, three chemical temporary storage compartments plus one compartment for storage of pressurized gas. This facility is situated in ground floor of Block 44, Agrotechnology and Biosciences Division, Dengkil Complex. Currently it houses a liquid scintillation counter, sample oxidizer, gas liquid chromatography, high performance liquid chromatography and auxiliary equipments. A road map for this laboratory will be discussed in relation with present scenario i.e. R and D service, training and consultancy provided by this laboratory; and future requirements and direction. (Author)

EPOS-WP16: A Platform for European Multi-scale Laboratories

Science.gov (United States)

Spiers, Chris; Drury, Martyn; Kan-Parker, Mirjam; Lange, Otto; Willingshofer, Ernst; Funiciello, Francesca; Rosenau, Matthias; Scarlato, Piergiorgio; Sagnotti, Leonardo; W16 Participants

2016-04-01

The participant countries in EPOS embody a wide range of world-class laboratory infrastructures ranging from high temperature and pressure experimental facilities, to electron microscopy, micro-beam analysis, analogue modeling and paleomagnetic laboratories. Most data produced by the various laboratory centres and networks are presently available only in limited "final form" in publications. As such many data remain inaccessible and/or poorly preserved. However, the data produced at the participating laboratories are crucial to serving society's need for geo-resources exploration and for protection against geo-hazards. Indeed, to model resource formation and system behaviour during exploitation, we need an understanding from the molecular to the continental scale, based on experimental data. This contribution will describe the work plans that the laboratories community in Europe is making, in the context of EPOS. The main objectives are: - To collect and harmonize available and emerging laboratory data on the properties and processes controlling rock system behaviour at multiple scales, in order to generate products accessible and interoperable through services for supporting research activities. - To co-ordinate the development, integration and trans-national usage of the major solid Earth Science laboratory centres and specialist networks. The length scales encompassed by the infrastructures included range from the nano- and micrometer levels (electron microscopy and micro-beam analysis) to the scale of experiments on centimetre sized samples, and to analogue model experiments simulating the reservoir scale, the basin scale and the plate scale. - To provide products and services supporting research into Geo-resources and Geo-storage, Geo-hazards and Earth System Evolution.

2016 Fermilab Laboratory Directed Research & Development Program Plan

Energy Technology Data Exchange (ETDEWEB)

Wester, W. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

2016-05-25

Fermilab is executing Laboratory Directed Research and Development (LDRD) as outlined by order DOE O 413.2B in order to enhance and realize the mission of the laboratory in a manner that also supports the laboratory’s strategic objectives and the mission of the Department of Energy. LDRD funds enable scientific creativity, allow for exploration of “high risk, high payoff” research, and allow for the demonstration of new ideas, technical concepts, and devices. LDRD also has an objective of maintaining and enhancing the scientific and technical vitality of Fermilab. LDRD is able to fund employee-initiated proposals that address the current strategic objectives and better position Fermilab for future mission needs. The request for such funds is made in consideration of the investment needs, affordability, and directives from DOE and Congress. Review procedures of the proposals will insure that those proposals which most address the strategic goals of the DOE and the Laboratory or which best position Fermilab for the future will be recommended to the Laboratory Director who has responsibility for approval. The execution of each approved project will be the responsibility of the Principal Investigator, PI, who will follow existing Laboratory guidelines to ensure compliance with safety, environmental, and quality assurance practices. A Laboratory Director-appointed LDRD Coordinator will work with Committees, Laboratory Management, other Fermilab Staff, and the PI’s to oversee the implementation of policies and procedures of LDRD and provide the management and execution of this Annual Program Plan. FY16 represents third fiscal year in which LDRD has existed at Fermilab. The number of preliminary proposals (117) submitted in response to the LDRD Call for Proposals indicates very strong interest of the program within the Fermilab community. The first two Calls have resulted in thirteen active LDRD projects – and it is expected that between five and seven new

Raising Virtual Laboratories in Australia onto global platforms

Science.gov (United States)

Wyborn, L. A.; Barker, M.; Fraser, R.; Evans, B. J. K.; Moloney, G.; Proctor, R.; Moise, A. F.; Hamish, H.

2016-12-01

Across the globe, Virtual Laboratories (VLs), Science Gateways (SGs), and Virtual Research Environments (VREs) are being developed that enable users who are not co-located to actively work together at various scales to share data, models, tools, software, workflows, best practices, etc. Outcomes range from enabling `long tail' researchers to more easily access specific data collections, to facilitating complex workflows on powerful supercomputers. In Australia, government funding has facilitated the development of a range of VLs through the National eResearch Collaborative Tools and Resources (NeCTAR) program. The VLs provide highly collaborative, research-domain oriented, integrated software infrastructures that meet user community needs. Twelve VLs have been funded since 2012, including the Virtual Geophysics Laboratory (VGL); Virtual Hazards, Impact and Risk Laboratory (VHIRL); Climate and Weather Science Laboratory (CWSLab); Marine Virtual Laboratory (MarVL); and Biodiversity and Climate Change Virtual Laboratory (BCCVL). These VLs share similar technical challenges, with common issues emerging on integration of tools, applications and access data collections via both cloud-based environments and other distributed resources. While each VL began with a focus on a specific research domain, communities of practice have now formed across the VLs around common issues, and facilitate identification of best practice case studies, and new standards. As a result, tools are now being shared where the VLs access data via data services using international standards such as ISO, OGC, W3C. The sharing of these approaches is starting to facilitate re-usability of infrastructure and is a step towards supporting interdisciplinary research. Whilst the focus of the VLs are Australia-centric, by using standards, these environments are able to be extended to analysis on other international datasets. Many VL datasets are subsets of global datasets and so extension to global is a

Pacific Northwest Laboratory annual report for 1988 to the DOE Office of Energy Research: Part 2, Environmental Sciences

Energy Technology Data Exchange (ETDEWEB)

1989-04-01

This report summarizes progress in environmental sciences research conducted by Pacific Northwest Laboratory (PNL) for the Office of Health and Environmental Research in FY 1988. Research is directed toward developing a fundamental understanding of processes controlling the long-term fate and biological effects of fugitive chemicals and other stressors resulting from energy development. The PNL research program continues to make important contributions to the resolution of important national environmental problems. The research, focused principally on subsurface contaminant transport and detection and management of human-induced changes in biological systems, forms the basis for defining and quantifying processes that affect humans and the environment at the regional and global levels. Each research project forms a component in an integrated laboratory- intermediated scale field approach designed to examine multiple phenomena at increasing levels of complexity. This approach is providing system-level insights into critical environmental processes. Strong university liaisons now in existence are being markedly expanded so that PNL resources and the specialized technical capabilities in the university community can be more efficiently integrated. Building on PNL technical strengths in geochemistry, environment microbiology, hydrodynamics, and statistical ecology, research in the environmental sciences is in an exciting phase, and new investments have been made in molecular sciences, chemistry, biotechnology, use of remote imagery, and theoretical ecology. The section on exploratory research provides unique insight into the value of these investments and into the future of PNL environmental sciences programs.

Annual report of Nuclear Engineering Research Laboratory, University of Tokyo in fiscal 1992

International Nuclear Information System (INIS)

1993-07-01

In this annual report, the activities of education and research, the state of operation of research facilities and others in Nuclear Engineering Research Laboratory, University of Tokyo in fiscal year 1992 are summarized. In this Laboratory, there are four large research facilities, that are, the fast neutron source reactor 'Yayoi', the electron beam linac, the nuclear fusion reactor blanket experiment facility and the heavy irradiation research facility. Those are used for carrying out education and research in the wide fields of nuclear engineering, and are offered also for joint utilization. The results of research by using respective research facilities have been summarized in separate reports. The course of the management and operation of each research facility is described, and the research activities, the theses for doctorate and graduation these of teachers, personnel and graduate students in the Laboratory are summarized. (J.P.N.)

From Research Resources to Learning Objects: Process Model and Virtualization Experiences

Science.gov (United States)

Sierra, Jose Luis; Fernandez-Valmayor, Alfredo; Guinea, Mercedes; Hernanz, Hector

2006-01-01

Typically, most research and academic institutions own and archive a great amount of objects and research related resources that have been produced, used and maintained over long periods of time by different types of "domain experts" (e.g. lecturers and researchers). Although the potential educational value of these resources is very…

Assessment of the Financial and Intellectual Value of a Research Library and its Application at the Idaho National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Lynn E. Melander

2012-08-01

Over the last several decades, libraries across the nation have undergone dramatic budget cuts, despite being an important resource for regional and national economic growth and innovation. Numerous studies have attempted to show that libraries increase the intellectual level of users and contribute to the economic growth of communities through surveys and customer service data. Within this study, we have attempted to develop a more analytical method for assessing library performance, using the Idaho National Laboratory Research Library as a sample subject. We have developed a mathematical model to measure the financial value of a library’s material resources as well as its intellectual value to determine if the library is a positive contributor to the wider organization and community it serves.

Laboratory directed research and development 2006 annual report.

Energy Technology Data Exchange (ETDEWEB)

Westrich, Henry Roger

2007-03-01

This report summarizes progress from the Laboratory Directed Research and Development (LDRD) program during fiscal year 2006. In addition to a programmatic and financial overview, the report includes progress reports from 430 individual R&D projects in 17 categories.

Use of Laboratory Animals in Biomedical and Behavioral Research

National Research Council Canada - National Science Library

1988-01-01

... of Laboratory Animals in Biomedical and Behavioral Research Commission on Life Sciences National Research Council Institute of Medicine NATIONAL ACADEMY PRESS Washington, D.C. 1988 Copyrightoriginal retained, the be not from cannot book, paper original however, for version formatting, authoritative the typesetting-specific created from the as publ...

Rocky Mountain Research Station: 2010 Research Accomplishments

Science.gov (United States)

Rick Fletcher

2010-01-01

The Rocky Mountain Research Station is one of seven regional units that make up the USDA Forest Service Research and Development organization ­ the most extensive natural resources research organization in the world. We maintain 12 field laboratories throughout a 12-state territory encompassing the Great Basin, Southwest, Rocky Mountains, and parts of the Great Plains...

LABORATORY DIRECTED RESEARCH AND DEVELOPMENT ANNUAL REPORT TO THE DOE - DECEMBER 2001

International Nuclear Information System (INIS)

FOX, K.J.

2001-01-01

Brookhaven National (BNL) Laboratory is a multidisciplinary laboratory that carries out basic and applied research in the physical, biomedical, and environmental sciences, and in selected energy technologies. It is managed by Brookhaven Science Associates, LLC, under contract with the U. S. Department of Energy. BNL's total annual budget has averaged about$450 million. There are about 3,000 employees, and another 4,500 guest scientists and students who come each year to use the Laboratory's facilities and work with the staff. The BNL Laboratory Directed Research and Development (LDRD) Program reports its status to the U.S. Department of Energy (DOE) annually in March, as required by DOE Order 4 13.2, ''Laboratory Directed Research and Development,'' March 5, 1997, and the LDRD Annual Report guidance, updated February 12, 1999. The LDRD Program obtains its funds through the Laboratory overhead pool and operates under the authority of DOE Order 4 13.2. The goals and objectives of BNL's LDRD Program can be inferred from the Program's stated purposes. These are to (1) encourage and support the development of new ideas and technology, (2) promote the early exploration and exploitation of creative and innovative concepts, and (3) develop new ''fundable'' R and D projects and programs. The emphasis is clearly articulated by BNL to be on supporting exploratory research ''which could lead to new programs, projects, and directions'' for the Laboratory. As one of the premier scientific laboratories of the DOE, BNL must continuously foster groundbreaking scientific research. At Brookhaven National Laboratory one such method is through its LDRD Program. This discretionary research and development tool is critical in maintaining the scientific excellence and long-term vitality of the Laboratory. Additionally, it is a means to stimulate the scientific community and foster new science and technology ideas, which becomes a major factor in achieving and maintaining staff excellence

Overview of DOE Oil and Gas Field Laboratory Projects

Science.gov (United States)

Bromhal, G.; Ciferno, J.; Covatch, G.; Folio, E.; Melchert, E.; Ogunsola, O.; Renk, J., III; Vagnetti, R.

2017-12-01

America's abundant unconventional oil and natural gas (UOG) resources are critical components of our nation's energy portfolio. These resources need to be prudently developed to derive maximum benefits. In spite of the long history of hydraulic fracturing, the optimal number of fracturing stages during multi-stage fracture stimulation in horizontal wells is not known. In addition, there is the dire need of a comprehensive understanding of ways to improve the recovery of shale gas with little or no impacts on the environment. Research that seeks to expand our view of effective and environmentally sustainable ways to develop our nation's oil and natural gas resources can be done in the laboratory or at a computer; but, some experiments must be performed in a field setting. The Department of Energy (DOE) Field Lab Observatory projects are designed to address those research questions that must be studied in the field. The Department of Energy (DOE) is developing a suite of "field laboratory" test sites to carry out collaborative research that will help find ways of improving the recovery of energy resources as much as possible, with as little environmental impact as possible, from "unconventional" formations, such as shale and other low permeability rock formations. Currently there are three field laboratories in various stages of development and operation. Work is on-going at two of the sites: The Hydraulic Fracturing Test Site (HFTS) in the Permian Basin and the Marcellus Shale Energy and Environmental Lab (MSEEL) project in the Marcellus Shale Play. Agreement on the third site, the Utica Shale Energy and Environmental Lab (USEEL) project in the Utica Shale Play, was just recently finalized. Other field site opportunities may be forthcoming. This presentation will give an overview of the three field laboratory projects.

Ultra-Short-Pulse Laser Effects Research and Analysis Laboratory

Data.gov (United States)

Federal Laboratory Consortium — FUNCTION: Enables research into advanced laser countermeasure techniques.DESCRIPTION: This laser facility has a capability to produce very high peak power levels of...

Aespoe hard rock laboratory. Current research projects 1998

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-12-31

In 1986 SKB decided to construct the Aespoe Hard Rock Laboratory (HRL) in order to provide an opportunity for research, development and demonstration in a realistic and undisturbed underground rock environment down to the depth planned for the future deep repository. The focus of current and future work is on development and testing of site characterization methods, verification of models describing the function of the natural and engineered barriers and development, testing, and demonstration of repository technology. The program has been organised so that all important steps in the development of a repository are covered, in other words the Aespoe HRL constitutes a `dress rehearsal` for the Swedish deep geological repository for spent fuel and other long-lived waste. Geoscientific investigations on Aespoe and nearby islands began in 1986. Aespoe was selected as the site for the laboratory in 1988. Construction of the facility, which reaches a depth of 460 m below the surface, began in 1990 and was completed in 1995. A major milestone had been reached in 1996 with the completion of the pre-investigation and construction phases of the Aespoe HRL. The comprehensive research conducted has permitted valuable development and verification of site characterization methods applied from the ground surface, boreholes, and underground excavations. The results of this research are summarised in the book `Aespoe Hard Rock Laboratory - 10 years of Research` published by SKB in 1996. The Operating Phase of the Aespoe HRL began in 1995 and is expected to continue for 15-20 years, that is until the first stage of the development of the Swedish deep geological repository for spent nuclear fuel is expected to be completed. A number of research projects were initiated at the start of the Operating Phase. Most of these projects have made substantial progress since then and important results have been obtained. The purpose of this brochure is to provide a brief presentation of the

Aespoe hard rock laboratory. Current research projects 1998

International Nuclear Information System (INIS)

1998-01-01

In 1986 SKB decided to construct the Aespoe Hard Rock Laboratory (HRL) in order to provide an opportunity for research, development and demonstration in a realistic and undisturbed underground rock environment down to the depth planned for the future deep repository. The focus of current and future work is on development and testing of site characterization methods, verification of models describing the function of the natural and engineered barriers and development, testing, and demonstration of repository technology. The program has been organised so that all important steps in the development of a repository are covered, in other words the Aespoe HRL constitutes a 'dress rehearsal' for the Swedish deep geological repository for spent fuel and other long-lived waste. Geoscientific investigations on Aespoe and nearby islands began in 1986. Aespoe was selected as the site for the laboratory in 1988. Construction of the facility, which reaches a depth of 460 m below the surface, began in 1990 and was completed in 1995. A major milestone had been reached in 1996 with the completion of the pre-investigation and construction phases of the Aespoe HRL. The comprehensive research conducted has permitted valuable development and verification of site characterization methods applied from the ground surface, boreholes, and underground excavations. The results of this research are summarised in the book 'Aespoe Hard Rock Laboratory - 10 years of Research' published by SKB in 1996. The Operating Phase of the Aespoe HRL began in 1995 and is expected to continue for 15-20 years, that is until the first stage of the development of the Swedish deep geological repository for spent nuclear fuel is expected to be completed. A number of research projects were initiated at the start of the Operating Phase. Most of these projects have made substantial progress since then and important results have been obtained. The purpose of this brochure is to provide a brief presentation of the