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Sample records for resolution beam profile

  1. Construction of a high resolution electron beam profile monitor

    International Nuclear Information System (INIS)

    Norem, J.; Dawson, J.; Haberichter, W.; Novak, W.; Reed, L.; Yang, X.F.

    1993-01-01

    Bremsstrahlung from an electron beam on a heavy target can be used to image the beam profile using collimators and slits. The limiting resolution using this system is determined by Fresnel diffraction, and is ∼ √(λd/2), where λ is the photon wavelength and d is determined by the linear dimensions of the system. For linear colliders this resolution could be a few nm. The highest resolution requires detectors which see only high energy, (small λ), photons, and this is accomplished by converting photons to pairs, and detecting Cherenkov light in a nearly forward angle with a CCD detector or streak camera. Tests are planned at the Argonne APS and SLAC FFTB

  2. A high resolution beam profile monitor using Bremsstrahlung

    International Nuclear Information System (INIS)

    Norem, J.

    1988-01-01

    The development of efficient high energy linear colliders in the 1 TeV range requires final focus systems capable of producing beam spot sizes on the order of 1--20 nm, about three orders of magnitude smaller than those produced at the SLC. Although beam line designs exist which can, in principle, produce the required optics, the construction of quadrupoles with the size and precision required will be challenging. Field errors in these quads must be small and should be verified experimentally, which is difficult with existing technology. This paper describes a proposal to use bremsstrahlung from heavy targets to measure high energy beam profiles and positions with a resolution approaching a few nm. The method is also applicable to tests of other final focus systems (flat beams, plasma lenses) at lower energies. 6 refs., 3 figs., 1 tab

  3. A high resolution, single bunch, beam profile monitor

    International Nuclear Information System (INIS)

    Norem, J.

    1992-01-01

    We developed a beam monitoring system which could be used to measure beam profile, size and stability at the final forms of a beamline or collider. The system uses nonimaging bremsstrahlung optics. The immediate use for this system would be examining the final focus spot at the SLAC/FFTR

  4. A high resolution, single bunch, beam profile monitor

    International Nuclear Information System (INIS)

    Norem, J.

    1992-01-01

    Efficient linear colliders require very small beam spots to produce high luminosities with reasonable input power, which limits the number of electrons which can be accelerated to high energies. The small beams, in turn, require high precision and stability in all accelerator components. Producing, monitoring and maintaining beams of the required quality has been, and will continue to be, difficult. A beam monitoring system which could be used to measure beam profile, size and stability at the final focus of a beamline or collider has been developed and is described here. The system uses nonimaging bremsstrahlung optics. The immediate use for this system would be examining the final focus spot at the SLAC/FFTB. The primary alternatives to this technique are those proposed by P. Chen / J. Buon, which analyses the energy and angular distributions of ion recoils to determine the aspect ratio of the electron bunch, and a method proposed by Shintake, which measures intensity variation of compton backscattered photons as the beam is moved across a pattern of standing waves produced by a laser

  5. Development of a high-resolution electron-beam profile monitor using Fresnel zone plates

    International Nuclear Information System (INIS)

    Nakamura, Norio; Sakai, Hiroshi; Muto, Toshiya; Hayano, Hitoshi

    2004-01-01

    We present a high-resolution and real-time beam profile monitor using Fresnel zone plates (FZPs) developed in the KEK-ATF damping ring. The monitor system has an X-ray imaging optics with two FZPs. In this monitor, the synchrotron radiation from the electron beam at the bending magnet is monochromatized by a crystal monochromator and the transverse electron beam image is twenty-times magnified by the two FZPs and detected on an X-ray CCD camera. The expected spatial resolution for the selected photon energy of 3.235 keV is less than 1 μm. With the beam profile monitor, we succeeded in obtaining a clear electron-beam image and measuring the extremely small beam size less than 10 μm. It is greatly expected that the beam profile monitor will be used in high-brilliance light sources and low-emittance accelerators. (author)

  6. Longitudinal profile diagnostic scheme with subfemtosecond resolution for high-brightness electron beams

    Directory of Open Access Journals (Sweden)

    G. Andonian

    2011-07-01

    Full Text Available High-resolution measurement of the longitudinal profile of a relativistic electron beam is of utmost importance for linac based free-electron lasers and other advanced accelerator facilities that employ ultrashort bunches. In this paper, we investigate a novel scheme to measure ultrashort bunches (subpicosecond with exceptional temporal resolution (hundreds of attoseconds and dynamic range. The scheme employs two orthogonally oriented deflecting sections. The first imparts a short-wavelength (fast temporal resolution horizontal angular modulation on the beam, while the second imparts a long-wavelength (slow angular kick in the vertical dimension. Both modulations are observable on a standard downstream screen in the form of a streaked sinusoidal beam structure. We demonstrate, using scaled variables in a quasi-1D approximation, an expression for the temporal resolution of the scheme and apply it to a proof-of-concept experiment at the UCLA Neptune high-brightness injector facility. The scheme is also investigated for application at the SLAC NLCTA facility, where we show that the subfemtosecond resolution is sufficient to resolve the temporal structure of the beam used in the echo-enabled free-electron laser. We employ beam simulations to verify the effect for typical Neptune and NLCTA parameter sets and demonstrate the feasibility of the concept.

  7. High-resolution velocimetry in energetic tidal currents using a convergent-beam acoustic Doppler profiler

    Science.gov (United States)

    Sellar, Brian; Harding, Samuel; Richmond, Marshall

    2015-08-01

    An array of single-beam acoustic Doppler profilers has been developed for the high resolution measurement of three-dimensional tidal flow velocities and subsequently tested in an energetic tidal site. This configuration has been developed to increase spatial resolution of velocity measurements in comparison to conventional acoustic Doppler profilers (ADPs) which characteristically use divergent acoustic beams emanating from a single instrument. This is achieved using geometrically convergent acoustic beams creating a sample volume at the focal point of 0.03 m3. Away from the focal point, the array is also able to simultaneously reconstruct three-dimensional velocity components in a profile throughout the water column, and is referred to herein as a convergent-beam acoustic Doppler profiler (C-ADP). Mid-depth profiling is achieved through integration of the sensor platform with the operational commercial-scale Alstom 1 MW DeepGen-IV Tidal Turbine deployed at the European Marine Energy Center, Orkney Isles, UK. This proof-of-concept paper outlines the C-ADP system configuration and comparison to measurements provided by co-installed reference instrumentation. Comparison of C-ADP to standard divergent ADP (D-ADP) velocity measurements reveals a mean difference of 8 mm s-1, standard deviation of 18 mm s-1, and an order of magnitude reduction in realisable length scale. C-ADP focal point measurements compared to a proximal single-beam reference show peak cross-correlation coefficient of 0.96 over 4.0 s averaging period and a 47% reduction in Doppler noise. The dual functionality of the C-ADP as a profiling instrument with a high resolution focal point make this configuration a unique and valuable advancement in underwater velocimetry enabling improved quantification of flow turbulence. Since waves are simultaneously measured via profiled velocities, pressure measurements and surface detection, it is expected that derivatives of this system will be a powerful tool in

  8. High resolution beam profiling of X-ray free electron laser radiation by polymer imprint development.

    Science.gov (United States)

    Rösner, Benedikt; Döring, Florian; Ribič, Primož R; Gauthier, David; Principi, Emiliano; Masciovecchio, Claudio; Zangrando, Marco; Vila-Comamala, Joan; De Ninno, Giovanni; David, Christian

    2017-11-27

    High resolution metrology of beam profiles is presently a major challenge at X-ray free electron lasers. We demonstrate a characterization method based on beam imprints in poly (methyl methacrylate). By immersing the imprints formed at 47.8 eV into organic solvents, the regions exposed to the beam are removed similar to resist development in grayscale lithography. This allows for extending the sensitivity of the method by more than an order of magnitude compared to the established analysis of imprints created solely by ablation. Applying the Beer-Lambert law for absorption, the intensity distribution in a micron-sized focus can be reconstructed from one single shot with a high dynamic range, exceeding 10 3 . The procedure described here allows for beam characterization at free electron lasers revealing even faint beam tails, which are not accessible when using ablation imprint methods. We demonstrate the greatly extended dynamic range on developed imprints taken in focus of conventional Fresnel zone plates and spiral zone plates producing beams with a topological charge.

  9. A high resolution wire scanner beam profile monitor with a microprocessor data acquisition system

    International Nuclear Information System (INIS)

    Cutler, R.I.; Mohr, D.L.; Whittaker, J.K.; Yoder, N.R.

    1983-01-01

    A beam profile monitor has been constructed for the NBS-LANL Racetrack Microtron. The monitor consists of two perpendicular 30 μm diameter carbon wires that are driven through an electron beam by a pneumatic actuator. A long-lifetime, electroformed nickel bellows is used for the linear-motion vacuum feedthrough. Secondary emission current from the wires and a signal from a transducer measuring the position of the wires are simultaneously digitized by a microprocessor to yield beam current density profiles in two dimensions. The wire scanner is designed for use with both pulsed and cw beams

  10. Spatial and temporal beam profile monitor with nanosecond resolution for CERN's Linac4 and Superconducting Proton Linac

    CERN Document Server

    Hori, M

    2008-01-01

    The Linac4, now being developed at CERN, will provide 160-MeV H- beams of high intensity . Before this beam can be injected into the CERN Proton Synchrotron Booster or future Superconducting Proton Linac for further acceleration, some sequences of 500-ps-long micro-bunches must be removed from it, using a beam chopper. These bunches, if left in the beam, would fall outside the longitudinal acceptance of the accelerators and make them radioactive. We developed a monitor to measure the time structure and spatial profile of this chopped beam, with respective resolutions and . Its large active area and dynamic range also allows investigations of beam halos. The ion beam first struck a carbon foil, and secondary electrons emerging from the foil were accelerated by a series of parallel grid electrodes. These electrons struck a phosphor screen, and the resulting image of the scintillation light was guided to a thermoelectrically cooled, charge-coupled device camera. The time resolution was attained by applying high-...

  11. Monitor of SC beam profiles

    CERN Document Server

    CERN PhotoLab

    1977-01-01

    A high-resolution secondary emission grid for the measurement of SC beam profiles. Modern techniques of metal-ceramic bonding, developed for micro-electronics, have been used in its construction. (See Annual Report 1977 p. 105 Fig. 12.)

  12. Simple beam profile monitor

    Energy Technology Data Exchange (ETDEWEB)

    Gelbart, W.; Johnson, R. R.; Abeysekera, B. [ASD Inc. Garden Bay, BC (Canada); Best Theratronics Ltd Ottawa Ontario (Canada); PharmaSpect Ltd., Burnaby BC (Canada)

    2012-12-19

    An inexpensive beam profile monitor is based on the well proven rotating wire method. The monitor can display beam position and shape in real time for particle beams of most energies and beam currents up to 200{mu}A. Beam shape, position cross-section and other parameters are displayed on a computer screen.

  13. If Frisch is true - impacts of varying beam width, resolution, frequency combinations and beam overlap when retrieving liquid water content profiles

    Science.gov (United States)

    Küchler, N.; Kneifel, S.; Kollias, P.; Loehnert, U.

    2017-12-01

    Cumulus and stratocumulus clouds strongly affect the Earth's radiation budget and are a major uncertainty source in weather and climate prediction models. To improve and evaluate models, a comprehensive understanding of cloud processes is necessary and references are needed. Therefore active and passive microwave remote sensing of clouds can be used to derive cloud properties such as liquid water path and liquid water content (LWC), which can serve as a reference for model evaluation. However, both the measurements and the assumptions when retrieving physical quantities from the measurements involve uncertainty sources. Frisch et al. (1998) combined radar and radiometer observations to derive LWC profiles. Assuming their assumptions are correct, there will be still uncertainties regarding the measurement setup. We investigate how varying beam width, temporal and vertical resolutions, frequency combinations, and beam overlap of and between the two instruments influence the retrieval of LWC profiles. Especially, we discuss the benefit of combining vertically, high resolved radar and radiometer measurements using the same antenna, i.e. having ideal beam overlap. Frisch, A. S., G. Feingold, C. W. Fairall, T. Uttal, and J. B. Snider, 1998: On cloud radar and microwave radiometer measurements of stratus cloud liquid water profiles. J. Geophys. Res.: Atmos., 103 (18), 23 195-23 197, doi:0148-0227/98/98JD-01827509.00.

  14. GANIL beam profile detectors

    International Nuclear Information System (INIS)

    Tribouillard, C.

    1997-01-01

    In the design phase of GANIL which started in 1977, one of the priorities of the project management was equipping the beamlines with a fast and efficient system for visualizing the beam position, thus making possible adjustment of the beam transport lines optics and facilitating beam control. The implantation of some thirty detectors was foreseen in the initial design. The assembly of installed detectors (around 190) proves the advantages of these detectors for displaying all the beams extracted from GANIL: transfer and transport lines, beam extracted from SISSI, very high intensity beam, secondary ion beams from the production target of the LISE and SPEG spectrometers, different SPIRAL project lines. All of these detectors are based on standard characteristics: - standard flange diameter (DN 160) with a standard booster for all the sensors; - identical analog electronics for all the detectors, with networking; - unique display system. The new micro-channel plate non-interceptive detectors (beam profile and ion packet lengths) make possible in-line control of the beam quality and accelerator stability. (author)

  15. Beam profile monitor

    International Nuclear Information System (INIS)

    Krausse, G.J.; Gram, P.A.M.

    1978-05-01

    A system used to monitor secondary beam profiles at the LAMPF Linac for channel tune-up and diagnostics is described. The multiwire proportional chamber design is discussed, and descriptions and drawings of the gate card, the amplifier/multiplexer card, the output amplifier card, and the overall system are given

  16. 3D Terahertz Beam Profiling

    DEFF Research Database (Denmark)

    Pedersen, Pernille Klarskov; Strikwerda, Andrew; Jepsen, Peter Uhd

    2013-01-01

    We present a characterization of THz beams generated in both a two-color air plasma and in a LiNbO3 crystal. Using a commercial THz camera, we record intensity images as a function of distance through the beam waist, from which we extract 2D beam profiles and visualize our measurements into 3D beam...

  17. Beam profile measurements using nonimaging gamma optics

    International Nuclear Information System (INIS)

    Norem, J.; Dawson, J.; Haberichter, W.; Lam, R.; Reed, L.; Yang, X.F.; Spencer, J.

    1995-01-01

    High energy photons produced from bremsstrahlung foils, Compton scattering or beamstrahlung from high energy e + e - collisions can be used to measure beam profiles using nonimaging optics. We describe the method and its limitations (resolution, backgrounds etc.), as well as the apparatus required to implement it. Data from a low energy test run is described as well as other possible applications, such as a 250+250 GeV linear collider and possible experiments with existing beams. (orig.)

  18. Beam profile measurements on RHIC

    International Nuclear Information System (INIS)

    Connolly, R.; Michnoff, R.; Moore, T.; Shea, T.; Tepikian, S.

    2000-01-01

    The Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Lab was commissioned during the summer of 1999. Transverse beam profiles on RHIC are measured with ionization profile monitors (IPMs). An IPM measures beam profiles by collecting the electrons liberated by residual gas ionization by the beam. The detector is placed in the gap of a dipole magnet to force the electrons to travel in straight lines from the beamline center to the collector. One IPM was tested and it measured the profiles of a single gold bunch containing 10 8 ions on consecutive turns. We show an example of one of these profiles giving transverse emittance. Also several profiles are combined into a mountain-range plot which shows betatron oscillations at injection

  19. Improving depth resolutions in positron beam spectroscopy by concurrent ion-beam sputtering

    Science.gov (United States)

    John, Marco; Dalla, Ayham; Ibrahim, Alaa M.; Anwand, Wolfgang; Wagner, Andreas; Böttger, Roman; Krause-Rehberg, Reinhard

    2018-05-01

    The depth resolution of mono-energetic positron annihilation spectroscopy using a positron beam is shown to improve by concurrently removing the sample surface layer during positron beam spectroscopy. During ion-beam sputtering with argon ions, Doppler-broadening spectroscopy is performed with energies ranging from 3 keV to 5 keV allowing for high-resolution defect studies just below the sputtered surface. With this technique, significantly improved depth resolutions could be obtained even at larger depths when compared to standard positron beam experiments which suffer from extended positron implantation profiles at higher positron energies. Our results show that it is possible to investigate layered structures with a thickness of about 4 microns with significantly improved depth resolution. We demonstrated that a purposely generated ion-beam induced defect profile in a silicon sample could be resolved employing the new technique. A depth resolution of less than 100 nm could be reached.

  20. Profiling hydrogen in materials using ion beams

    International Nuclear Information System (INIS)

    Ziegler, J.F.; Wu, C.P.; Williams, P.

    1977-01-01

    Over the last few years many ion beam techniques have been reported for the profiling of hydrogen in materials. Nine of these were evaluated using similar samples of hydrogen ion-implanted into silicon. When possible the samples were analyzed using two or more techniques to confirm the ion-implanted accuracy. The results of this analysis which has produced a consensus profile of H in silicon which is useful as a calibration standard are reported. The analytical techniques used have capabilities ranging from very high depth resolution (approximately 50 A) and high sensitivity (less than 1 ppM) to deep probes for hydrogen which can sample throughout thin sheets

  1. Optical circular deflector with attosecond resolution for ultrashort electron beam

    Directory of Open Access Journals (Sweden)

    Zhen Zhang

    2017-05-01

    Full Text Available A novel method using high-power laser as a circular deflector is proposed for the measurement of femtosecond (fs and sub-fs electron beam. In the scheme, the electron beam interacts with a laser pulse operating in a radially polarized doughnut mode (TEM_{01^{*}} in a helical undulator, generating angular kicks along the beam in two directions at the same time. The phase difference between the two angular kicks makes the beam form a ring after a propagation section with appropriate phase advance, which can reveal the current profile of the electron beam. Detailed theoretical analysis of the method and numerical results with reasonable parameters are both presented. It is shown that the temporal resolution can reach up to ∼100 attosecond, which is a significant improvement for the diagnostics of ultrashort electron beam.

  2. Beam profile measurement with flying wires at the Fermilab Recycler Ring

    Energy Technology Data Exchange (ETDEWEB)

    Carcagno, R.; Pishchalnikov, Yu.; Krider, J.; Hu, M.; Lorman, E.; Marchionni, A.; Pordes, S.; Wilson, P.; Zagel, J.; /Fermilab

    2005-05-01

    Flying wires were installed at the Fermilab Recycler Ring for transverse beam profile measurement for both proton and antiproton beams. The following note describes the system configuration, calibration and resolution of the flying wire system, interactions between the wires and the beam, as well as analysis of the transverse beam profile in the presence of a stochastic cooling system.

  3. Beam profile measurement with flying wires at the Fermilab Recycler Ring

    International Nuclear Information System (INIS)

    Carcagno, R.; Pishchalnikov, Yu.; Krider, J.; Hu, M.; Lorman, E.; Marchionni, A.; Pordes, S.; Wilson, P.; Zagel, J.

    2005-01-01

    Flying wires were installed at the Fermilab Recycler Ring for transverse beam profile measurement for both proton and antiproton beams. The following note describes the system configuration, calibration and resolution of the flying wire system, interactions between the wires and the beam, as well as analysis of the transverse beam profile in the presence of a stochastic cooling system

  4. Spatial resolution test of a beam diagnostic system for DESIREE

    Science.gov (United States)

    Das, Susanta; Kallberg, A.

    2010-11-01

    A diagnostic system based on the observation of low energy ( ˜ 10 eV) secondary electrons (SE) produced by a beam, striking a metallic foil has been built to monitor and to cover the wide range of beam intensities and energies for Double ElectroStatic Ion Ring ExpEriment [1,2].The system consists of a Faraday cup to measure the beam current, a collimator with circular apertures of different diameters to measure the spatial resolution of the system, a beam profile monitoring system (BPMS), and a control unit. The BPMS, in turn, consists of an aluminim (Al) foil, a grid placed in front of the Al foil to accelerate the SE, position sensitive MCP, fluorescent screen, and a CCD camera to capture the images. The collimator contains a set of circular holes of different diameters and separations (d) between them. The collimator cuts out from the beam areas equal to the holes with separation d mm between the beams centers and creates well separated (distinguishable) narrow beams of approximately same intensity close to each other. A 10 keV proton beam was used. The spatial resolution of the system was tested for different Al plate and MCP voltages and resolution of better than 2 mm was achieved. Ref.: 1. K. Kruglov {et al}., NIM A 441 (2000) 595; 701 (2002) 193c, 2. MSL and Atomic Physics, Stockholm Univ.(www.msl.se, http://www.atom.physto.se/Cederquist/desiree/web/hc.html).

  5. High resolution laser spectroscopy as a diagnostic tool in beams

    International Nuclear Information System (INIS)

    Bergmann, K.; Hefter, U.; Hering, P.

    1977-01-01

    The combination of high resolution laser spectroscopy with the technique of molecular beams allows a very detailed beam research since molecules or atoms in specific quantum states can be sampled yielding previously unavailable sources of data. In these experiments a Na/Na 2 beam emerges from a 0.2 mm nozzle and is collimated by a 2 mm wide slit 50 cm downstream. To probe the molecules a single mode Ar + -laser was used which can be tuned within the gain profile of the laser line (8 GHz) to several transitions between specific levels in the ground state and second electronically excited state of the Na 2 molecule. (Auth.)

  6. Wire Scanner Beam Profile Measurements: LANSCE Facility Beam Development

    International Nuclear Information System (INIS)

    Gilpatrick, John D.; Batygin, Yuri K.; Gonzales, Fermin; Gruchalla, Michael E.; Kutac, Vincent G.; Martinez, Derwin; Sedillo, James Daniel; Pillai, Chandra; Rodriguez Esparza, Sergio; Smith, Brian G.

    2012-01-01

    The Los Alamos Neutron Science Center (LANSCE) is replacing Wire Scanner (WS) beam profile measurement systems. Three beam development tests have taken place to test the new wire scanners under beam conditions. These beam development tests have integrated the WS actuator, cable plant, electronics processors and associated software and have used H - beams of different beam energy and current conditions. In addition, the WS measurement-system beam tests verified actuator control systems for minimum profile bin repeatability and speed, checked for actuator backlash and positional stability, tested the replacement of simple broadband potentiometers with narrow band resolvers, and tested resolver use with National Instruments Compact Reconfigurable Input and Output (cRIO) Virtual Instrumentation. These beam tests also have verified how trans-impedance amplifiers react with various types of beam line background noise and how noise currents were not generated. This paper will describe these beam development tests and show some resulting data.

  7. Wire Scanner Beam Profile Measurements: LANSCE Facility Beam Development

    Energy Technology Data Exchange (ETDEWEB)

    Gilpatrick, John D. [Los Alamos National Laboratory; Batygin, Yuri K. [Los Alamos National Laboratory; Gonzales, Fermin [Los Alamos National Laboratory; Gruchalla, Michael E. [Los Alamos National Laboratory; Kutac, Vincent G. [Los Alamos National Laboratory; Martinez, Derwin [Los Alamos National Laboratory; Sedillo, James Daniel [Los Alamos National Laboratory; Pillai, Chandra [Los Alamos National Laboratory; Rodriguez Esparza, Sergio [Los Alamos National Laboratory; Smith, Brian G. [Los Alamos National Laboratory

    2012-05-15

    The Los Alamos Neutron Science Center (LANSCE) is replacing Wire Scanner (WS) beam profile measurement systems. Three beam development tests have taken place to test the new wire scanners under beam conditions. These beam development tests have integrated the WS actuator, cable plant, electronics processors and associated software and have used H{sup -} beams of different beam energy and current conditions. In addition, the WS measurement-system beam tests verified actuator control systems for minimum profile bin repeatability and speed, checked for actuator backlash and positional stability, tested the replacement of simple broadband potentiometers with narrow band resolvers, and tested resolver use with National Instruments Compact Reconfigurable Input and Output (cRIO) Virtual Instrumentation. These beam tests also have verified how trans-impedance amplifiers react with various types of beam line background noise and how noise currents were not generated. This paper will describe these beam development tests and show some resulting data.

  8. A beam profile monitor for a tagged photon beam

    International Nuclear Information System (INIS)

    Arends, J.; Breuer, M.; Dahmen, H.D.; Detemple, P.; Noeldeke, G.; Schneider, W.; Zucht, B.

    1990-10-01

    A beam profile monitor for electron and photon beams is described, which operates at the low intensities encountered in a tagged bremsstrahlung beam environment, typically 10 10 electrons/s and 10 7 photons/s. The method is based on a wire scanner and utilizes the presence of a tagging spectrometer. The accuracy of the measurements can be tuned in a wide range (at the expense of measuring time) to meet the requirements set by the actual beam size. Examples of measured electron and photon beam profiles at the tagged photon beam of the PHOENICS experiment at the electron stretcher ring ELSA are given. (orig.)

  9. A beam profile monitor for a tagged photon beam

    Energy Technology Data Exchange (ETDEWEB)

    Arends, J.; Breuer, M.; Dahmen, H.D.; Detemple, P.; Noeldeke, G.; Schneider, W.; Zucht, B.

    1990-10-01

    A beam profile monitor for electron and photon beams is described, which operates at the low intensities encountered in a tagged bremsstrahlung beam environment, typically 10{sup 10} electrons/s and 10{sup 7} photons/s. The method is based on a wire scanner and utilizes the presence of a tagging spectrometer. The accuracy of the measurements can be tuned in a wide range (at the expense of measuring time) to meet the requirements set by the actual beam size. Examples of measured electron and photon beam profiles at the tagged photon beam of the PHOENICS experiment at the electron stretcher ring ELSA are given. (orig.).

  10. Beam profile monitors for a tagged photon beam facility

    International Nuclear Information System (INIS)

    Arends, J.; Breuer, M.; Dahmen, H.D.; Detemple, P.; Schneider, W.; Urban, D.; Zucht, B.

    1991-01-01

    A beam profile monitor for electron and photon beams is described, which operates at the low intensities encountered in a tagged bremsstrahlung beam environment, typically 10 10 electrons/s and 10 7 photons/s. The method is based on a wire scanner and utilizes the presence of a tagging spectrometer. The accuracy of the measurements can be tuned in a wide range to meet the requirements set by the actual beam parameters. Examples of measured electron and photon beam profiles at the tagged photon beam of the PHOENICS experiment at the electron stretcher ring ELSA in Bonn are given. (orig.)

  11. Acquisition and display of beam profilers

    International Nuclear Information System (INIS)

    David, L.; Duneau, P.; Lecorche, E.; Lermine, P.; Vila, J.; Maugeais, C.; Ulrich, M.

    1995-01-01

    The ion beam adjustment requires the knowledge of its shape (its profile). A new electronic interface has been developed for the older multiwire profiles, while an other electronic equipment has been developed for the gas profiles and the microchannel plates. The data from these interfaces are computed to get numerical values and profile shapes, then transmitted by the network to the main control room to be displayed (shapes and data) on every workstation, by different beam tuning programs. (author)

  12. Beam profile monitors in the NLCTA

    International Nuclear Information System (INIS)

    Nantista, C.; Adolphsen, C.; Brown, R.L.; Fuller, R.; Rifkin, J.

    1997-05-01

    The transverse current profile in the Next Linear Collider Test Accelerator (NLCTA) electron beam can be monitored at several locations along the beam line by means of profile monitors. These consist of insertable phosphor screens, light collection and transport systems, CID cameras, a frame-grabber, and PC and VAX based image analysis software. In addition to their usefulness in tuning and steering the accelerator, the profile monitors are utilized for emittance measurement. A description of these systems and their performance is presented

  13. Ionization beam profile monitor for operation under hard environmental conditions

    International Nuclear Information System (INIS)

    Teterev, Yu.G.; Kaminski, G.; Phi Thanh Huong; Kaminski, G.; Kozik, E.

    2010-01-01

    The design and the performance of the Ionization Beam Profile Monitor (IBPM) operating on the residual gas ionization principle are described. The main advantage of the constructed device is the non-contact measuring method. Operating under hard environmental conditions it delivers the information about the primary beam position, profile and intensity in 'on-line' regime. It was found out that the device is capable to operate in vacuum in the range of 10 -6 /10 -3 mbar without the loss of the resolution power at the beam current as low as a few nA. The IBPM is prospective for beam profile monitoring due to long time. Emergency situations do not lead to decrease of its operability.

  14. Position sensitive detector used to detect beam profile

    International Nuclear Information System (INIS)

    Zhao Xiaoyan; Zhao Zhizheng; Zu Kailing; Zheng Jianhua; Wang Yifang

    2003-01-01

    In order to study the detecting system of the residual-gas beam profile, we introduce the principle and construction of the Position Sensitive Detector (PSD). The performance of PSD is tested. Position resolution, position linearity, detection efficiency and background are obtained

  15. Quantitative high dynamic range beam profiling for fluorescence microscopy

    International Nuclear Information System (INIS)

    Mitchell, T. J.; Saunter, C. D.; O’Nions, W.; Girkin, J. M.; Love, G. D.

    2014-01-01

    Modern developmental biology relies on optically sectioning fluorescence microscope techniques to produce non-destructive in vivo images of developing specimens at high resolution in three dimensions. As optimal performance of these techniques is reliant on the three-dimensional (3D) intensity profile of the illumination employed, the ability to directly record and analyze these profiles is of great use to the fluorescence microscopist or instrument builder. Though excitation beam profiles can be measured indirectly using a sample of fluorescent beads and recording the emission along the microscope detection path, we demonstrate an alternative approach where a miniature camera sensor is used directly within the illumination beam. Measurements taken using our approach are solely concerned with the illumination optics as the detection optics are not involved. We present a miniature beam profiling device and high dynamic range flux reconstruction algorithm that together are capable of accurately reproducing quantitative 3D flux maps over a large focal volume. Performance of this beam profiling system is verified within an optical test bench and demonstrated for fluorescence microscopy by profiling the low NA illumination beam of a single plane illumination microscope. The generality and success of this approach showcases a widely flexible beam amplitude diagnostic tool for use within the life sciences

  16. Ion beam profiling from the interaction with a freestanding 2D layer

    Directory of Open Access Journals (Sweden)

    Ivan Shorubalko

    2017-03-01

    Full Text Available Recent years have seen a great potential of the focused ion beam (FIB technology for the nanometer-scale patterning of a freestanding two-dimensional (2D layer. Experimentally determined sputtering yields of the perforation process can be quantitatively explained using the binary collision theory. The main peculiarity of the interaction between the ion beams and the suspended 2D material lies in the absence of collision cascades, featured by no interaction volume. Thus, the patterning resolution is directly set by the beam diameters. Here, we demonstrate pattern resolution beyond the beam size and precise profiling of the focused ion beams. We find out that FIB exposure time of individual pixels can influence the resultant pore diameter. In return, the pore dimension as a function of the exposure dose brings out the ion beam profiles. Using this method of determining an ion-beam point spread function, we verify a Gaussian profile of focused gallium ion beams. Graphene sputtering yield is extracted from the normalization of the measured Gaussian profiles, given a total beam current. Interestingly, profiling of unbeknown helium ion beams in this way results in asymmetry of the profile. Even triangular beam shapes are observed at certain helium FIB conditions, possibly attributable to the trimer nature of the beam source. Our method of profiling ion beams with 2D-layer perforation provides more information on ion beam profiles than the conventional sharp-edge scan method does.

  17. Beam profile effects on NPB [neutral particle beam] performance

    International Nuclear Information System (INIS)

    LeClaire, R.J. Jr.

    1988-03-01

    A comparison of neutral particle beam brightness for various neutral beam profiles indicates that the widely used assumption of a Gaussian profile may be misleading for collisional neutralizers. An analysis of available experimental evidence shows that lower peaks and higher tails, compared to a Gaussian beam profile, are observed out of collisional neutralizers, which implies that peak brightness is over estimated, and for a given NPB platform-to-target range, the beam current (power), dwell time or some combination of such engagement parameters would have to be altered to maintain a fixed dose on target. Based on the present analysis, this factor is nominally about 2.4 but may actually be as low as 1.8 or as high as 8. This is an important consideration in estimating NPB constellation performance in SDI engagement contexts. 2 refs., 6 figs

  18. Estimation and display of beam density profiles

    Energy Technology Data Exchange (ETDEWEB)

    Dasgupta, S; Mukhopadhyay, T; Roy, A; Mallik, C

    1989-03-15

    A setup in which wire-scanner-type beam-profile monitor data are collected on-line in a nuclear data-acquisition system has been used and a simple algorithm for estimation and display of the current density distribution in a particle beam is described.

  19. Vibrating wire for beam profile scanning

    Directory of Open Access Journals (Sweden)

    S. G. Arutunian

    1999-12-01

    Full Text Available A method that measures the transverse profile (emittance of the bunch by detecting radiation arising at the scattering of the bunch on scanning wire is widely used. In this work information about bunch scattering is obtained by measuring the oscillation frequency of the tightened scanning wire. In such a way, the system of radiation (or secondary particles extraction and measurement can be removed. The entire unit consists of a compact fork with tightened wire and a scanning system. Normal oscillation frequency of a wire depends on wire tension, its geometric parameters, and, in a second approximation, its elastic characteristics. Normal oscillations are generated by interaction of an alternating current through the wire with magnetic field of a permanent magnet. In this case, it is suggested that the magnetic field of the accelerator (field of dipole magnets or quadrupole magnets be used for excitation of oscillations. The dependence of oscillation frequency on beam scattering is determined by several factors, including changes of wire tension caused by transverse force of the beam and influence of beam self-field. Preliminary calculations show that the influence of wire heating will dominate. We have studied strain gauges on the basis of vibrating wire from various materials (tungsten, beryl bronze, and niobium zirconium alloys. A scheme of normal oscillation generation by alternating current in autogeneration circuit with automatic frequency adjustment was selected. A special method of wire fixation and elimination of transverse degrees of freedom allows us to achieve relative stability better than 10^{-5} during several days at a relative resolution of 10^{-6}. Experimental results and estimates of wire heating of existing scanners show that the wire heats up to a few hundred grades, which is enough for measurements. The usage of wire of micrometer thickness diminishes the problem of wire thermalization speed during the scanning of the bunch.

  20. A beam profile monitor for small electron beams

    International Nuclear Information System (INIS)

    Norem, J.

    1991-01-01

    Measurement of beam properties at the foci of high energy linacs is difficult due to the small size of the waists in proposed and existing accelerators (1 nm -2 μm). This article considers the use of bremsstrahlung radiation from thin foils to measure the size and phase space density these beams using nonimaging optics. The components of the system are described, and the ultimate resolution, evaluated theoretically for the case of the Final Focus Test Beam (FFTB) at Stanford Linear Accelerator Center, is a few nm

  1. A beam profile monitor for small electron beams

    International Nuclear Information System (INIS)

    Norem, J.

    1991-01-01

    Measurement of beam properties at the foci of high energy linacs is difficult due to the small size of the waists in proposed and existing accelerators (1 nm - 2 μ). This paper considers the use of bremsstrahlung radiation from thin foils to measure the size and phase space density these beams using nonimaging optics. The components of the system are described, and the ultimate resolution, evaluated theoretically for the case of the Final Focus Test Beam at Stanford Linear Accelerator Center, is a few nm. 13 refs., 4 figs. 1 tab

  2. An Electron-Beam Profile Monitor Using Fresnel Zone Plates

    International Nuclear Information System (INIS)

    Nakamura, Norio; Sakai, Hiroshi; Iida, Kensuke; Shinoe, Kenji; Takaki, Hiroyuki; Fujisawa, Masami; Hayano, Hitoshi; Muto, Toshiya; Nomura, Masaharu; Kamiya, Yukihide; Koseki, Tadashi; Amemiya, Yoshiyuki; Aoki, Nobutada; Nakayama, Koichi

    2004-01-01

    We have developed a beam profile monitor using two Fresnel zone plates (FZPs) at the KEK-ATF (Accelerator Test Facility) damping ring to measure small electron-beam sizes for low-emittance synchrotron radiation sources. The monitor has a structure of an X-ray microscope, where two FZPs constitute an X-ray imaging optics. In the monitor system, the synchrotron radiation from the electron beam at the bending magnet is monochromatized to 3.235-keV X-rays by a crystal monochromator and the transverse electron-beam image is twenty-times magnified by the two FZPs and detected on an X-ray CCD camera. This monitor has the following advantages: (1) high spatial resolution, (2) non-destructive measurement, (3) real-time monitoring, and (4) direct electron-beam imaging. With the beam profile monitor, we have succeeded in obtaining a clear electron-beam image and measuring the extremely small beam size less than 10 μm. The measured magnification of the imaging optics was in good agreement with the design value

  3. Beam profiles for fast neutrons; and reply

    International Nuclear Information System (INIS)

    Bewley, D.K.; Parnell, C.J.; Bloch, P.

    1976-01-01

    The authors express surprise that Bloch et al. (Bloch, P.H., Hendry, G.O., Hilton, J.L., Quam, W.M., Reinhard, D.K., and Wilson, C., 1976, Phys. Med. Biol., Vol. 21, 450) justified a target size of 5.5 x 5.5 cm in a neutron generator by comparison with the profile given by a 2.5 MV X-ray generator. The penumbral width of this new neutron generator is more than twice that of a modern megavoltage X-ray machine, and larger than those of beams from standard 60 Co units, or of the Hammersmith Hospital cyclotron beam. The large target size of the neutron generator may have to be accepted as a necessary evil, but should not be considered satisfactory. In reply, one of the authors of the original note presents the results of calculations of beam profiles for 14 MeV neutron beams in a tissue-equivalent phantom, and suggests that the broader profiles are principally caused by the larger probability of side scatter, not by source size. The most fruitful approach to sharpening the neutron beam profile would seem to be to design a field flattening filter to increase relative dose near the edge inside the geometrically defined field. Calculations indicating that Bewley and Parnell have underestimated the penumbral widths of 60 Co beams are also presented. (U.K.)

  4. Beam Profile Measurement with Flying Wires at the Fermilab Recycler Ring

    CERN Document Server

    Hu, Martin; Krider, John; Lorman, Eugene; Marchionni, Alberto; Pishchalnikov, Yu M; Pordes, Stephen; Slimmer, David; Wilson, Peter R; Zagel, James

    2005-01-01

    The Fermilab Recycler Ring is a high vacuum fixed energy antiproton storage ring with stochastic and electron cooling systems. Flying wires were installed at the Fermilab Recycler Ring for transverse beam profile measurement. The following note describes the system configuration, calibration and resolution of the flying wire system, as well as analysis of the transverse beam profile in the presence of both cooling systems.

  5. An online, energy-resolving beam profile detector for laser-driven proton beams

    Energy Technology Data Exchange (ETDEWEB)

    Metzkes, J.; Rehwald, M.; Obst, L.; Schramm, U. [Helmholtz-Zentrum Dresden–Rossendorf (HZDR), Bautzner Landstr. 400, 01328 Dresden (Germany); Technische Universität Dresden, 01062 Dresden (Germany); Zeil, K.; Kraft, S. D.; Sobiella, M.; Schlenvoigt, H.-P. [Helmholtz-Zentrum Dresden–Rossendorf (HZDR), Bautzner Landstr. 400, 01328 Dresden (Germany); Karsch, L. [OncoRay-National Center for Radiation Research in Oncology, Technische Universität Dresden, 01307 Dresden (Germany)

    2016-08-15

    In this paper, a scintillator-based online beam profile detector for the characterization of laser-driven proton beams is presented. Using a pixelated matrix with varying absorber thicknesses, the proton beam is spatially resolved in two dimensions and simultaneously energy-resolved. A thin plastic scintillator placed behind the absorber and read out by a CCD camera is used as the active detector material. The spatial detector resolution reaches down to ∼4 mm and the detector can resolve proton beam profiles for up to 9 proton threshold energies. With these detector design parameters, the spatial characteristics of the proton distribution and its cut-off energy can be analyzed online and on-shot under vacuum conditions. The paper discusses the detector design, its characterization and calibration at a conventional proton source, as well as the first detector application at a laser-driven proton source.

  6. Fast-scan, beam-profile monitor

    International Nuclear Information System (INIS)

    Waugh, A.F.

    1977-01-01

    A minimodular, data-acquisition system can be used to rapidly interrogate a 45-point matrix of beam-current sampling targets over the 3- x 12-in. rectangular, output beam cross section of a 50-A, neutral-beam ion source. This system, operating at a throughput rate of 12 μs per channel, can make several complete scans during the 10- to 25-ms-duration beam pulse. Data obtained are available in both analog and digital form. The analog signal is used to create an immediately interpretable CRT display of the beam-current density profile that shows how well the source is aimed. The digital data are held in buffer memory until transfer to a minicomputer for software processing and plotting

  7. Automated translating beam profiler for in situ laser beam spot-size and focal position measurements

    Science.gov (United States)

    Keaveney, James

    2018-03-01

    We present a simple and convenient, high-resolution solution for automated laser-beam profiling with axial translation. The device is based on a Raspberry Pi computer, Pi Noir CMOS camera, stepper motor, and commercial translation stage. We also provide software to run the device. The CMOS sensor is sensitive over a large wavelength range between 300 and 1100 nm and can be translated over 25 mm along the beam axis. The sensor head can be reversed without changing its axial position, allowing for a quantitative estimate of beam overlap with counter-propagating laser beams. Although not limited to this application, the intended use for this device is the automated measurement of the focal position and spot-size of a Gaussian laser beam. We present example data of one such measurement to illustrate device performance.

  8. Measurement of an electron-beam size with a beam profile monitor using Fresnel zone plates

    International Nuclear Information System (INIS)

    Iida, K.; Nakamura, N.; Sakai, H.; Shinoe, K.; Takaki, H.; Fujisawa, M.; Hayano, H.; Nomura, M.; Kamiya, Y.; Koseki, T.; Amemiya, Y.; Aoki, N.; Nakayama, K.

    2003-01-01

    We present a non-destructive and real-time beam profile monitor using Fresnel zone plates (FZPs) and the measurement of an electron-beam size with this monitor in the KEK-Accelerator Test Facility (ATF) damping ring. The monitor system has the structure of a long-distance X-ray microscope, where two FZPs constitute an X-ray imaging optics. The synchrotron radiation from the electron beam at the bending magnet is monochromatized by a crystal monochromator and the transverse electron beam image is twenty times magnified by the two FZPs and detected on an X-ray CCD camera. The expected spatial resolution for the selected photon energy of 3.235 keV is sufficiently high to measure the horizontal and vertical beam sizes of the ATF damping ring. With the beam profile monitor, we succeeded in obtaining a clear electron-beam image and measuring the extremely small beam size less than 10 μm. The measured magnification of the X-ray imaging optics in the monitor system was in good agreement with the design value

  9. Beam profile for Malaysian electron accelerator

    International Nuclear Information System (INIS)

    Abu Bakar Ghazali; Muhamad Zahidee Taat

    2007-01-01

    This paper comprises of two calculations that require in designing a dose profile for an electron accelerator machine before its fabrication. The first is to calculate the beam deflection due to changes of high voltage (HV) supply as well as the deflection coil currents so that the electron beam will only scan at the window foil of 18 cm length and 6 cm width. Secondly, we also require to calculate the beam profile at 50 mm underneath the window foil. The electron gun that produces a beam of 10 mm diameter has to be oscillated in a sawtooth wave for the prescribed window size at frequencies of 50 Hz and 400 Hz along the length and width directions respectively. For the beam deflection, we apply a basic formula from Lorentz force law to obtain a set of HV supply and the coil current that is suitable for both deflections and this result can assist in designing the coil current against HV changes via an electronic controller. The dose profile was calculated using the RMS current formulation along the length direction. We found that the measured and the calculated RMS currents are in comparable for the case of 1 MeV, 50 mA accelerator facility that is going to be installed at Nuclear Malaysia complex. A similar measurement will be carried out for our locally designed accelerator of 150 KeV, 10 mA after fabrication and installation of the machine are completed. (Author)

  10. Electron beam based transversal profile measurements of intense ion beams

    International Nuclear Information System (INIS)

    El Moussati, Said

    2014-01-01

    A non-invasive diagnostic method for the experimental determination of the transverse profile of an intense ion beam has been developed and investigated theoretically as well as experimentally within the framework of the present work. The method is based on the deflection of electrons when passing the electromagnetic field of an ion beam. To achieve this an electron beam is employed with a specifically prepared transversal profile. This distinguish this method from similar ones which use thin electron beams for scanning the electromagnetic field [Roy et al. 2005; Blockland10]. The diagnostic method presented in this work will be subsequently called ''Electron-Beam-Imaging'' (EBI). First of all the influence of the electromagnetic field of the ion beam on the electrons has been theoretically analyzed. It was found that the magnetic field causes only a shift of the electrons along the ion beam axis, while the electric field only causes a shift in a plane transverse to the ion beam. Moreover, in the non-relativistic case the magnetic force is significantly smaller than the Coulomb one and the electrons suffer due to the magnetic field just a shift and continue to move parallel to their initial trajectory. Under the influence of the electric field, the electrons move away from the ion beam axis, their resulting trajectory shows a specific angle compared to the original direction. This deflection angle practically depends just on the electric field of the ion beam. Thus the magnetic field has been neglected when analysing the experimental data. The theoretical model provides a relationship between the deflection angle of the electrons and the charge distribution in the cross section of the ion beam. The model however only can be applied for small deflection angles. This implies a relationship between the line-charge density of the ion beam and the initial kinetic energy of the electrons. Numerical investigations have been carried out to clarify the

  11. High power beam profile monitor with optical transition radiation

    International Nuclear Information System (INIS)

    Denard, J.C.; Piot, P.; Capek, K.; Feldl, E.

    1997-01-01

    A simple monitor has been built to measure the profile of the high power beam (800 kW) delivered by the CEBAF accelerator at Jefferson Lab. The monitor uses the optical part of the forward transition radiation emitted from a thin carbon foil. The small beam size to be measured, about 100 μm, is challenging not only for the power density involved but also for the resolution the instrument must achieve. An important part of the beam instrumentation community believes the radiation being emitted into a cone of characteristic angle 1/γ is originated from a region of transverse dimension roughly λγ; thus the apparent size of the source of transition radiation would become very large for highly relativistic particles. This monitor measures 100 μm beam sizes that are much smaller than the 3.2 mm λγ limit; it confirms the statement of Rule and Fiorito that optical transition radiation can be used to image small beams at high energy. The present paper describes the instrument and its performance. The authors tested the foil in, up to 180 μA of CW beam without causing noticeable beam loss, even at 800 MeV, the lowest CEBAF energy

  12. OTR profile measurement of a LINAC electron beam with portable ultra high-speed camera

    International Nuclear Information System (INIS)

    Mogi, T.; Nisiyama, S.; Tomioka, S.; Enoto, T.

    2004-01-01

    We have studied on and developed a portable ultra high-speed camera, and so applied to measurement of a LINAC electron beam. We measured spatial OTR profiles of a LINAC electron beam using this camera with temporal resolution 80ns. (author)

  13. Characterization of the Li beam probe with a beam profile monitor on JET.

    Science.gov (United States)

    Nedzelskiy, I S; Korotkov, A; Brix, M; Morgan, P; Vince, J

    2010-10-01

    The lithium beam probe (LBP) is widely used for measurements of the electron density in the edge plasma of magnetically confined fusion experiments. The quality of LBP data strongly depends on the stability and profile shape of the beam. The main beam parameters are as follows: beam energy, beam intensity, beam profile, beam divergence, and the neutralization efficiency. For improved monitoring of the beam parameters, a beam profile monitor (BPM) from the National Electrostatics Corporation (NEC) has been installed in the Li beam line at JET. In the NEC BPM, a single grounded wire formed into a 45° segment of a helix is rotated by a motor about the axis of the helix. During each full revolution, the wire sweeps twice across the beam to give X and Y profiles. In this paper, we will describe the properties of the JET Li beam as measured with the BPM and demonstrate that it facilitates rapid optimization of the gun performance.

  14. Profiles of an initially perturbed electron beam

    International Nuclear Information System (INIS)

    Abdelsalam, F.W.

    1991-01-01

    This paper discusses the solutions for the profiles of an electron beam which is launched into a constant magnetic field with an initial boundary slope and injected with a radius which is greater or less than the cathode radius. It has been found that the outermost electron traces sine waves and executes limited excursions when the initial boundary slope corresponds to angles up to 1 degree, no matter whether the initial radius is 0.90 or 1.10 times the radius of the cathode. For initial inclination angles close to 2 degrees, the beam boundary does not preserve a sinusoidal shape, this statement holds true for focusing magnetic flux densities varying from 200x10 -4 to 700x10 -4 weber per square meter

  15. Beam-scanning system for determination of beam profiles and form factors in merged-beam experiments

    International Nuclear Information System (INIS)

    Keyser, C.J.; Froelich, H.R.; Mitchell, J.B.A.; McGowan, J.W.

    1979-01-01

    A beam-scanning system for a merged electron-ion beam experiment is described. This system is used to determine the horizontal and vertical beam profiles and the form factors at three different locations along the axis of the beams. Design details of the wedge-shaped scanners and the electronic circuit for obtaining beam profiles and form factors are described. The form factor derivation for merged beams is given and an expression in terms of measured quantities is derived. (author)

  16. High resolution, position sensitive detector for energetic particle beams

    International Nuclear Information System (INIS)

    Marsh, E.P.; Strathman, M.D.; Reed, D.A.; Odom, R.W.; Morse, D.H.; Pontau, A.E.

    1993-01-01

    The performance and design of an imaging position sensitive, particle beam detector will be presented. The detector is minimally invasive, operates a wide dynamic range (>10 10 ), and exhibits high spatial resolution. The secondary electrons produced when a particle beam passes through a thin foil are imaged using stigmatic ion optics onto a two-dimensional imaging detector. Due to the low scattering cross section of the 6 nm carbon foil the detector is a minimal perturbation on the primary beam. A prototype detector with an image resolution of approximately 5 μm for a field of view of 1 mm has been reported. A higher resolution detector for imaging small beams (<50 μm) with an image resolution of better than 0.5 μm has since been developed and its design is presented. (orig.)

  17. High resolution, position sensitive detector for energetic particle beams

    Energy Technology Data Exchange (ETDEWEB)

    Marsh, E P [Charles Evans and Associates, Redwood City, CA (United States); Strathman, M D [Charles Evans and Associates, Redwood City, CA (United States); Reed, D A [Charles Evans and Associates, Redwood City, CA (United States); Odom, R W [Charles Evans and Associates, Redwood City, CA (United States); Morse, D H [Sandia National Labs., Livermore, CA (United States); Pontau, A E [Sandia National Labs., Livermore, CA (United States)

    1993-05-01

    The performance and design of an imaging position sensitive, particle beam detector will be presented. The detector is minimally invasive, operates a wide dynamic range (>10[sup 10]), and exhibits high spatial resolution. The secondary electrons produced when a particle beam passes through a thin foil are imaged using stigmatic ion optics onto a two-dimensional imaging detector. Due to the low scattering cross section of the 6 nm carbon foil the detector is a minimal perturbation on the primary beam. A prototype detector with an image resolution of approximately 5 [mu]m for a field of view of 1 mm has been reported. A higher resolution detector for imaging small beams (<50 [mu]m) with an image resolution of better than 0.5 [mu]m has since been developed and its design is presented. (orig.)

  18. Two-dimensional beam profiles and one-dimensional projections

    Science.gov (United States)

    Findlay, D. J. S.; Jones, B.; Adams, D. J.

    2018-05-01

    One-dimensional projections of improved two-dimensional representations of transverse profiles of particle beams are proposed for fitting to data from harp-type monitors measuring beam profiles on particle accelerators. Composite distributions, with tails smoothly matched on to a central (inverted) parabola, are shown to give noticeably better fits than single gaussian and single parabolic distributions to data from harp-type beam profile monitors all along the proton beam transport lines to the two target stations on the ISIS Spallation Neutron Source. Some implications for inferring beam current densities on the beam axis are noted.

  19. Exploitation of high resolution beam spectroscopy diagnostics on MAST

    Science.gov (United States)

    Michael, Clive; Debock, Maarten; Conway, Neil; Akers, Rob; Appel, Lynton; Field, Anthony; Walsh, Mike; Wisse, Marco

    2009-11-01

    Recent developments in beam spectroscopy on MAST, including CXRS, MSE and a pilot FIDA system have revealed new information about phenomena such as ITBs, MHD instabilities, transport and fast particle physics. For example, ITBs in the ion temperature and toroidal rotation have been observed with the 64ch CXRS system, while reverse-shear q profiles have been observed with the recently commissioned 35ch MSE system. Thus, the synergy of these diagnostics helps us to understand, among other things, the role of magnetic and rotational shear on ITBs. MSE measurements have also helped to understand MHD phenomena such as locked modes (characterized by changes in toroidal momentum, revealed by CXRS), sawteeth, and internal reconnection events. Finally, the temporal/spatial resolution and SNR of the MSE system have been exploited. Interesting results include the detection of low frequency (˜2kHz) magnetic field fluctuations, characterization of the radial structure of higher frequency (<100kHz) broadband and coherent density (BES) fluctuations, and the identification of short scale length features (˜1.8cm) in the current profile near the edge pedestal.

  20. High-resolution phylogenetic microbial community profiling

    Energy Technology Data Exchange (ETDEWEB)

    Singer, Esther; Coleman-Derr, Devin; Bowman, Brett; Schwientek, Patrick; Clum, Alicia; Copeland, Alex; Ciobanu, Doina; Cheng, Jan-Fang; Gies, Esther; Hallam, Steve; Tringe, Susannah; Woyke, Tanja

    2014-03-17

    The representation of bacterial and archaeal genome sequences is strongly biased towards cultivated organisms, which belong to merely four phylogenetic groups. Functional information and inter-phylum level relationships are still largely underexplored for candidate phyla, which are often referred to as microbial dark matter. Furthermore, a large portion of the 16S rRNA gene records in the GenBank database are labeled as environmental samples and unclassified, which is in part due to low read accuracy, potential chimeric sequences produced during PCR amplifications and the low resolution of short amplicons. In order to improve the phylogenetic classification of novel species and advance our knowledge of the ecosystem function of uncultivated microorganisms, high-throughput full length 16S rRNA gene sequencing methodologies with reduced biases are needed. We evaluated the performance of PacBio single-molecule real-time (SMRT) sequencing in high-resolution phylogenetic microbial community profiling. For this purpose, we compared PacBio and Illumina metagenomic shotgun and 16S rRNA gene sequencing of a mock community as well as of an environmental sample from Sakinaw Lake, British Columbia. Sakinaw Lake is known to contain a large age of microbial species from candidate phyla. Sequencing results show that community structure based on PacBio shotgun and 16S rRNA gene sequences is highly similar in both the mock and the environmental communities. Resolution power and community representation accuracy from SMRT sequencing data appeared to be independent of GC content of microbial genomes and was higher when compared to Illumina-based metagenome shotgun and 16S rRNA gene (iTag) sequences, e.g. full-length sequencing resolved all 23 OTUs in the mock community, while iTags did not resolve closely related species. SMRT sequencing hence offers various potential benefits when characterizing uncharted microbial communities.

  1. Fundamental limits to imaging resolution for focused ion beams

    International Nuclear Information System (INIS)

    Orloff, J.; Swanson, L.W.; Utlaut, M.

    1996-01-01

    This article investigates the limitations on the formation of focused ion beam images from secondary electrons. We use the notion of the information content of an image to account for the effects of resolution, contrast, and signal-to-noise ratio and show that there is a competition between the rate at which small features are sputtered away by the primary beam and the rate of collection of secondary electrons. We find that for small features, sputtering is the limit to imaging resolution, and that for extended small features (e.g., layered structures), rearrangement, redeposition, and differential sputtering rates may limit the resolution in some cases. copyright 1996 American Vacuum Society

  2. Performance of a high resolution cavity beam position monitor system

    Science.gov (United States)

    Walston, Sean; Boogert, Stewart; Chung, Carl; Fitsos, Pete; Frisch, Joe; Gronberg, Jeff; Hayano, Hitoshi; Honda, Yosuke; Kolomensky, Yury; Lyapin, Alexey; Malton, Stephen; May, Justin; McCormick, Douglas; Meller, Robert; Miller, David; Orimoto, Toyoko; Ross, Marc; Slater, Mark; Smith, Steve; Smith, Tonee; Terunuma, Nobuhiro; Thomson, Mark; Urakawa, Junji; Vogel, Vladimir; Ward, David; White, Glen

    2007-07-01

    It has been estimated that an RF cavity Beam Position Monitor (BPM) could provide a position measurement resolution of less than 1 nm. We have developed a high resolution cavity BPM and associated electronics. A triplet comprised of these BPMs was installed in the extraction line of the Accelerator Test Facility (ATF) at the High Energy Accelerator Research Organization (KEK) for testing with its ultra-low emittance beam. The three BPMs were each rigidly mounted inside an alignment frame on six variable-length struts which could be used to move the BPMs in position and angle. We have developed novel methods for extracting the position and tilt information from the BPM signals including a robust calibration algorithm which is immune to beam jitter. To date, we have demonstrated a position resolution of 15.6 nm and a tilt resolution of 2.1 μrad over a dynamic range of approximately ±20 μm.

  3. Real-time beam profile imaging system for actinotherapy accelerator

    International Nuclear Information System (INIS)

    Lin Yong; Wang Jingjin; Song Zheng; Zheng Putang; Wang Jianguo

    2003-01-01

    This paper describes a real-time beam profile imaging system for actinotheraphy accelerator. With the flash X-ray imager and the technique of digital image processing, a real-time 3-dimension dosage image is created from the intensity profile of the accelerator beam in real time. This system helps to obtain all the physical characters of the beam in any section plane, such as FWHM, penumbra, peak value, symmetry and homogeneity. This system has been used to acquire a 3-dimension dosage distribution of dynamic wedge modulator and the transient process of beam dosage. The system configure and the tested beam profile images are also presented

  4. Beam-energy and laser beam-profile monitor at the BNL LINAC

    Energy Technology Data Exchange (ETDEWEB)

    Connolly, R.; Briscoe, B.; Degen, C.; DeSanto, L.; Meng, W.; Minty, M.; Nayak, S.; Raparia, D.; Russo, T.

    2010-05-02

    We are developing a non-interceptive beam profile and energy monitor for H{sup -} beams in the high energy beam transport (HEBT) line at the Brookhaven National Lab linac. Electrons that are removed from the beam ions either by laser photodetachment or stripping by background gas are deflected into a Faraday cup. The beam profile is measured by stepping a narrow laser beam across the ion beam and measuring the electron charge vs. transverse laser position. There is a grid in front of the collector that can be biased up to 125kV. The beam energy spectrum is determined by measuring the electron charge vs. grid voltage. Beam electrons have the same velocity as the beam and so have an energy of 1/1836 of the beam protons. A 200MeV H{sup -} beam yields 109keV electrons. Energy measurements can be made with either laser-stripped or gas-stripped electrons.

  5. Beam envelope profile of non-centrosymmetric polygonal phase space

    International Nuclear Information System (INIS)

    Chen Yinbao; Xie Xi

    1984-01-01

    The general theory of beam envelope profile of non-centrosymmetric polygonal phase space is developed. By means of this theory the beam envelope profile of non-centrosymmetric polygonal phase space can be calculated directly. An example is carried out in detail to show the practical application of the theory

  6. Beam-profile monitor using a sodium-vapour

    CERN Multimedia

    1972-01-01

    Beam-profile monitor using a sodium-vapour curtain at 45 degrees to the ISR beam in Ring I (sodium generator is in white cylinder just left of centre). Electrons produced by ionization of the sodium vapour give an image of the beam on a fluorescent screen that is observed by a TV camera (at upper right).

  7. Excimer laser beam profile recording based on electrochemical etched polycarbonate

    International Nuclear Information System (INIS)

    Parvin, P.; Jaleh, B.; Zangeneh, H.R.; Zamanipour, Z.; Davoud-Abadi, Gh.R.

    2008-01-01

    There is no polymeric detector used to register the beam profile of UV lasers. Here, a method is proposed for the measurement of intensive UV beam pattern of the excimer lasers based on the photoablated polycarbonate detector after coherent UV exposure and the subsequent electrochemical etching. UV laser induced defects in the form of self-microstructuring on polycarbonate are developed to replicate the spatial intensity distribution as a beam profiler

  8. Excimer laser beam profile recording based on electrochemical etched polycarbonate

    Energy Technology Data Exchange (ETDEWEB)

    Parvin, P. [Physics Department, Amirkabir University of Technology, P.O. Box 15875-4413, Hafez Ave, Tehran (Iran, Islamic Republic of); Laser Research Center, AEOI, P.O. Box 1165-8486, Tehran (Iran, Islamic Republic of)], E-mail: parvin@aut.ac.ir; Jaleh, B. [Physics Department, Bu-Ali Sina University, Postal Code 65174, Hamedan (Iran, Islamic Republic of); Zangeneh, H.R. [Physics Department, Amirkabir University of Technology, P.O. Box 15875-4413, Hafez Ave, Tehran (Iran, Islamic Republic of); Zamanipour, Z. [Laser Research Center, AEOI, P.O. Box 1165-8486, Tehran (Iran, Islamic Republic of); Davoud-Abadi, Gh.R. [Physics Department, Amirkabir University of Technology, P.O. Box 15875-4413, Hafez Ave, Tehran (Iran, Islamic Republic of)

    2008-08-15

    There is no polymeric detector used to register the beam profile of UV lasers. Here, a method is proposed for the measurement of intensive UV beam pattern of the excimer lasers based on the photoablated polycarbonate detector after coherent UV exposure and the subsequent electrochemical etching. UV laser induced defects in the form of self-microstructuring on polycarbonate are developed to replicate the spatial intensity distribution as a beam profiler.

  9. A multi-wire beam profile monitor in the AGS

    Energy Technology Data Exchange (ETDEWEB)

    Huang, H.; Buxton, W.; Castillo, V.; Glenn, J.W. [and others

    1997-07-01

    A multi-wire beam profile monitor which can be used to directly monitor and control the optical matching between the Booster and AGS rings has been installed and tested in the AGS. Placement of a multi-wire monitor directly in the AGS provides profile measurements taken upon injection and the first two or more revolutions of the beam. The data from such measurements can be used to determine the optical properties of the beam transport line leading into the AGS.

  10. High resolution silicon detectors for colliding beam physics

    International Nuclear Information System (INIS)

    Amendolia, S.R.; Bedeschi, F.; Bertolucci, E.; Bettoni, D.; Bosisio, L.; Bottigli, U.; Bradaschia, C.; Dell'Orso, M.; Fidecaro, F.; Foa, L.; Focardi, E.; Giannetti, P.; Giorgi, M.A.; Marrocchesi, P.S.; Menzione, A.; Raso, G.; Ristori, L.; Scribano, A.; Stefanini, A.; Tenchini, R.; Tonelli, G.; Triggiani, G.

    1984-01-01

    Resolution and linearity of the position measurement of Pisa multi-electrode silicon detectors are presented. The detectors are operated in slightly underdepleted mode and take advantage of their intrinsic resistivity for resistive charge partition between adjacent strips. 22 μm resolution is achieved with readout lines spaced 300 μm. Possible applications in colliding beam experiments for the detection of secondary vertices are discussed. (orig.)

  11. Influence of laser beam profile on electromagnetically induced absorption

    International Nuclear Information System (INIS)

    Cuk, S. M.; Radonjic, M.; Krmpot, A. J.; Nikolic, S. N.; Grujic, Z. D.; Jelenkovic, B. M.

    2010-01-01

    We compared, experimentally and theoretically, Hanle electromagnetically induced absorption (EIA) obtained using Gaussian and Π-shaped laser beams 3 mm in diameter. The study was done by measuring the transmission of a laser locked to the F g =2→F e =3 transition at the D 2 line of 87 Rb in a vacuum cell. EIA linewidths obtained for the two laser profiles were significantly different in the range of laser intensities 1-4 mW/cm 2 . EIA with the Π-shaped laser beam has a broad intensity maximum and linewidths larger than those obtained with the Gaussian beam profile. We also studied Hanle EIA by measuring the transmission of selected segments of the entire laser beam by placing a small movable aperture in front of the detector. Waveforms so obtained in Hanle EIA resonances were strongly influenced both by the radial distance of the transmitted segment from the beam center and by the radial profile of the laser beam. We show that outer regions of Gaussian beam, and central regions of the Π-shaped beam generate the narrowest lines. The different behaviors of EIA owing to different beam profiles revealed by both theory and experiment indicate the importance of the radial profile of the laser beam for proper modeling of coherent effects in alkali metal vapors.

  12. LHC Beam Instrumentation: Beam Profile Measurements (2/3)

    CERN Document Server

    CERN. Geneva

    2014-01-01

    The LHC is equipped with a full suite of sophisticated beam instrumentation which has been essential for rapid commissioning, the safe increase in total stored beam power and the understanding of machine optics and accelerator physics phenomena. These lectures will introduce these systems and comment on their contributions to the various stages of beam operation. They will include details on: the beam position system and its use for real-time global orbit feedback; the beam loss system and its role in machine protection; total and bunch by bunch intensity measurements; tune measurement and feedback; diagnostics for transverse beam size measurements, abort gap monitoring and longitudinal density measurements. Issues and problems encountered along the way will also be discussed together with the prospect for future upgrades.

  13. Narrow nuclear resonance profiling of Al with subnanometric depth resolution

    International Nuclear Information System (INIS)

    Rosa, E.B.O. da; Krug, C.; Stedile, F.C.; Morais, J.; Baumvol, I.J.R.

    2002-01-01

    We report on the use of the narrow and isolated resonance at 404.9 keV in the cross-section curve of the 27 Al(p,γ) 28 Si nuclear reaction for profiling Al in ultrathin aluminum oxide films on Si. The samples were characterized as-deposited and after thermal annealing, so that Al transport could be studied. An estimated depth resolution of approximately 0.4 nm near the surface of the films could be obtained owing to: (i) the very small resonance width; (ii) the high stopping power of Al 2 O 3 for 404.9 keV protons; (iii) the high energy stability of the proton beam provided by the 500 kV HVEE ion implanter at Porto Alegre; and (iv) an apparent thickness magnification by a factor between 2.0 and 2.4 with the use of glancing incidence. This technique is compared to other methods for Al profiling like medium energy ion scattering and some sputtering-based techniques

  14. Resolution of a High Performance Cavity Beam Position Monitor System

    International Nuclear Information System (INIS)

    Walston, S.; Chung, C.; Fitsos, P.; Gronberg, J.; Ross, M.; Khainovski, O.; Kolomensky, Y.; Loscutoff, P.; Slater, M.; Thomson, M.; Ward, D.; Boogert, S.; Vogel, V.; Meller, R.; Lyapin, A.; Malton, S.; Miller, D.; Frisch, J.; Hinton, S.; May, J.; McCormick, D.; Smith, S.; Smith, T.; White, G.; Orimoto, T.; Hayano, H.; Honda, Y.; Terunuma, N.; Urakawa, J.

    2005-01-01

    International Linear Collider (ILC) interaction region beam sizes and component position stability requirements will be as small as a few nanometers. It is important to the ILC design effort to demonstrate that these tolerances can be achieved - ideally using beam-based stability measurements. It has been estimated that RF cavity beam position monitors (BPMs) could provide position measurement resolutions of less than one nanometer and could form the basis of the desired beam-based stability measurement. We have developed a high resolution RF cavity BPM system. A triplet of these BPMs has been installed in the extraction line of the KEK Accelerator Test Facility (ATF) for testing with its ultra-low emittance beam. A metrology system for the three BPMs was recently installed. This system employed optical encoders to measure each BPM's position and orientation relative to a zero-coefficient of thermal expansion carbon fiber frame and has demonstrated that the three BPMs behave as a rigid-body to less than 5 nm. To date, we have demonstrated a BPM resolution of less than 20 nm over a dynamic range of +/- 20 microns

  15. A beam profile monitor for heavy ion beams at high impact energies

    International Nuclear Information System (INIS)

    Hausmann, A.; Stiebing, K.E.; Bethge, K.; Froehlich, O.; Koehler, E.; Mueller, A.; Rueschmann, G.

    1994-01-01

    A beam profile monitor for heavy ion beams has been developed for the use in experiments at the Heavy Ion Synchrotron SIS at Gesellschaft fuer Schwerionenforschung Darmstadt (GSI). Four thin scintillation fibres are mounted on one wheel and scan the ion beam sequentially in two linearly independent directions. They are read out via one single photomultiplier common to all four fibres into one time spectrum, which provides all information about beam position, beam extension, time structure and lateral homogeneity of the beam. The system operates in a wide dynamic range of beam intensities. ((orig.))

  16. Influence of laser beam profiles on received power fluctuation

    Science.gov (United States)

    Dordova, Lucie; Diblik, Jan

    2011-09-01

    Gaussian beam is very often used for the transmission of information in optical wireless links. The usage of this optical beam has its advantages and, of course, disadvantages. This work focuses on possibilities of using laser beams with different distribution of optical intensity - Top Hat beam. Creation of the optical beam with selected optical intensity profile will be briefly described. Optical beams will propagate through the "clear" and stationary atmosphere in the experimental part of this work. These results will be compared with the data obtained after a laser beam is passed through the turbulent and attenuated atmosphere. We will use an ultrasound fog generator for laser beam attenuation testing. To create the turbulence, infra radiators will be applied. Particular results obtained from different atmospheric conditions will be compared and using different types of optical beams will be assessed.

  17. Ultra-low energy Ar+ beam applied for SIMS depth profile analysis of layered nanostructures

    International Nuclear Information System (INIS)

    Konarski, P.; Mierzejewska, A.; Iwanejko, I.

    2001-01-01

    Secondary ion mass spectrometry (SIMS) depth profile analyses of flat layered nanostructures: 10 nm Ta 2 O 3 /Ta and 20 nm (10 x B 4 C/Mo)/Si as well as microparticles of core (illite) - shell (rutile) structure, performed with the use of ultra-low energy ion beam (180-880 eV, Ar + ), are presented. The profiles were obtained using 'mesa' scanning technique and also sample rotation. Depth profile resolution below 1 nanometer was obtained for flat nanostructures. Presented experimental results are compared with Monte Carlo sputtering simulations of analysed structures. A method of finding beam energy, optimal for the best resolution SIMS depth profile analysis, is suggested. (author)

  18. Resolution and systematic limitations in beam based alignment

    Energy Technology Data Exchange (ETDEWEB)

    Tenenbaum, P.G.

    2000-03-15

    Beam based alignment of quadrupoles by variation of quadrupole strength is a widely-used technique in accelerators today. The authors describe the dominant systematic limitation of this technique, which arises from the change in the center position of the quadrupole as the strength is varied, and derive expressions for the resulting error. In addition, the authors derive an expression for the statistical resolution of such techniques in a periodic transport line, given knowledge of the line's transport matrices, the resolution of the beam position monitor system, and the details of the strength variation procedure. These results are applied to the Next Linear Collider main linear accelerator, an 11 kilometer accelerator containing 750 quadrupoles and 5,000 accelerator structures. The authors find that in principle a statistical resolution of 1 micron is easily achievable but the systematic error due to variation of the magnetic centers could be several times larger.

  19. Molecular depth profiling of trehalose using a C{sub 60} cluster ion beam

    Energy Technology Data Exchange (ETDEWEB)

    Wucher, Andreas [Department of Physics, University of Duisburg-Essen, D-47048 Duisburg (Germany)], E-mail: andreas.wucher@uni-due.de; Cheng Juan; Winograd, Nicholas [Department of Chemistry, Pennsylvania State University, University Park, PA 16802 (United States)

    2008-12-15

    Molecular depth profiling of organic overlayers was performed using a mass selected fullerene ion beam in conjunction with time-of-flight (TOF-SIMS) mass spectrometry. The characteristics of depth profiles acquired on a 300-nm trehalose film on Si were studied as a function of the impact kinetic energy and charge state of the C{sub 60} projectile ions. We find that the achieved depth resolution depends only weakly upon energy.

  20. Techniques for intense-proton-beam profile measurements

    International Nuclear Information System (INIS)

    Gilpatrick, J.D.

    1998-01-01

    In a collaborative effort with industry and several national laboratories, the Accelerator Production of Tritium (APT) facility and the Spallation Neutron Source (SNS) linac are presently being designed and developed at Los Alamos National Laboratory (LANL). The APT facility is planned to accelerate a 100-mA H + cw beam to 1.7 GeV and the SNS linac is planned to accelerate a 1- to 4-mA-average, H - , pulsed-beam to 1 GeV. With typical rms beam widths of 1- to 3-mm throughout much of these accelerators, the maximum average-power densities of these beams are expected to be approximately 30- and 1-MW-per-square millimeter, respectively. Such power densities are too large to use standard interceptive techniques typically used for acquisition of beam profile information. This paper summarizes the specific requirements for the beam profile measurements to be used in the APT, SNS, and the Low Energy Development Accelerator (LEDA)--a facility to verify the operation of the first 20-MeV section of APT. This paper also discusses the variety of profile measurement choices discussed at a recent high-average-current beam profile workshop held in Santa Fe, NM, and will present the present state of the design for the beam profile measurements planned for APT, SNS, and LEDA

  1. Development of high-resolution x-ray CT system using parallel beam geometry

    Energy Technology Data Exchange (ETDEWEB)

    Yoneyama, Akio, E-mail: akio.yoneyama.bu@hitachi.com; Baba, Rika [Central Research Laboratory, Hitachi Ltd., Hatoyama, Saitama (Japan); Hyodo, Kazuyuki [Institute of Materials Science, High Energy Accelerator Research Organization, Tsukuba, Ibaraki (Japan); Takeda, Tohoru [School of Allied Health Sciences, Kitasato University, Sagamihara, Kanagawa (Japan); Nakano, Haruhisa; Maki, Koutaro [Department of Orthodontics, School of Dentistry Showa University, Ota-ku, Tokyo (Japan); Sumitani, Kazushi; Hirai, Yasuharu [Kyushu Synchrotron Light Research Center, Tosu, Saga (Japan)

    2016-01-28

    For fine three-dimensional observations of large biomedical and organic material samples, we developed a high-resolution X-ray CT system. The system consists of a sample positioner, a 5-μm scintillator, microscopy lenses, and a water-cooled sCMOS detector. Parallel beam geometry was adopted to attain a field of view of a few mm square. A fine three-dimensional image of birch branch was obtained using a 9-keV X-ray at BL16XU of SPring-8 in Japan. The spatial resolution estimated from the line profile of a sectional image was about 3 μm.

  2. High resolution muon computed tomography at neutrino beam facilities

    International Nuclear Information System (INIS)

    Suerfu, B.; Tully, C.G.

    2016-01-01

    X-ray computed tomography (CT) has an indispensable role in constructing 3D images of objects made from light materials. However, limited by absorption coefficients, X-rays cannot deeply penetrate materials such as copper and lead. Here we show via simulation that muon beams can provide high resolution tomographic images of dense objects and of structures within the interior of dense objects. The effects of resolution broadening from multiple scattering diminish with increasing muon momentum. As the momentum of the muon increases, the contrast of the image goes down and therefore requires higher resolution in the muon spectrometer to resolve the image. The variance of the measured muon momentum reaches a minimum and then increases with increasing muon momentum. The impact of the increase in variance is to require a higher integrated muon flux to reduce fluctuations. The flux requirements and level of contrast needed for high resolution muon computed tomography are well matched to the muons produced in the pion decay pipe at a neutrino beam facility and what can be achieved for momentum resolution in a muon spectrometer. Such an imaging system can be applied in archaeology, art history, engineering, material identification and whenever there is a need to image inside a transportable object constructed of dense materials

  3. Fast ion profiles during neutral beam and lower hybrid heating

    International Nuclear Information System (INIS)

    Heidbrink, W.W.; Strachan, J.D.; Bell, R.E.; Cavallo, A.; Motley, R.; Schilling, G.; Stevens, J.; Wilson, J.R.

    1985-07-01

    Profiles of the d(d,p)t fusion reaction are measured in the PLT tokamak using an array of collimated 3 MeV proton detectors. During deuterium neutral beam injection, the emission profile indicates that the beam deposition is at least as narrow as predicted by a bounce-averaged Fokker-Planck code. The fast ion tail formed by lower hybrid waves (at densities above the critical density for current drive) also peaks strongly near the magnetic axis

  4. IFMIF-LIPAc Beam Diagnostics. Profiling and Loss Monitoring Systems

    International Nuclear Information System (INIS)

    Egberts, J.

    2012-01-01

    The IFMIF accelerator will accelerate two 125 mA continuous wave (cw) deuteron beams up to 40 MeV and blasts them onto a liquid lithium target to release neutrons. The very high beam power of 10 MW pose unprecedented challenges for the accelerator development. Therefore, it was decided to build a prototype accelerator, the Linear IFMIF Prototype Accelerator (LIPAc), which has the very same beam characteristic, but is limited to 9 MeV only. In the frame of this thesis, diagnostics devices for IFMIF and LIPAc have been developed. The diagnostics devices consist of beam loss monitors and interceptive as well as non-interceptive profile monitors. For the beam loss monitoring system, ionization chambers and diamond detectors have been tested and calibrated for neutron and γ radiation in the energy range expected at LIPAc. During these tests, for the first time, diamond detectors were successfully operated at cryogenic temperatures. For the interceptive profilers, thermal simulations were performed to ensure safe operation. For the non-interceptive profiler, Ionization Profile Monitors (IPMs) were developed. A prototype has been built and tested, and based on the findings, the final IPMs were designed and built. To overcome the space charge of accelerator beam, a software algorithm was written to reconstruct the actual beam profile. (author) [fr

  5. Polystyrene negative resist for high-resolution electron beam lithography

    Directory of Open Access Journals (Sweden)

    Ma Siqi

    2011-01-01

    Full Text Available Abstract We studied the exposure behavior of low molecular weight polystyrene as a negative tone electron beam lithography (EBL resist, with the goal of finding the ultimate achievable resolution. It demonstrated fairly well-defined patterning of a 20-nm period line array and a 15-nm period dot array, which are the densest patterns ever achieved using organic EBL resists. Such dense patterns can be achieved both at 20 and 5 keV beam energies using different developers. In addition to its ultra-high resolution capability, polystyrene is a simple and low-cost resist with easy process control and practically unlimited shelf life. It is also considerably more resistant to dry etching than PMMA. With a low sensitivity, it would find applications where negative resist is desired and throughput is not a major concern.

  6. Beam profile measurements on the advanced test accelerator using optical techniques

    International Nuclear Information System (INIS)

    Chong, Y.P.; Kalibjian, R.; Cornish, J.P.; Kallman, J.S.; Donnelly, D.

    1986-01-01

    Beam current density profiles of ATA have been measured both spatially and temporally using a number of diagnostics. An extremely important technique involves measuring optical emissions from either a target foil inserted into the beam path or gas atoms and molecules excited by beam electrons. This paper describes the detection of the optical emission. A 2-D gated television camera with a single or dual micro-channel-plate (MCP) detector for high gain provides excellent spatial and temporal resolution. Measurements are routinely made with resolutions of 1 mm and 5 ns respectively. The optical line of sight allows splitting part of the signal to a streak camera or photometer for even higher time resolution

  7. Dual resolution cone beam breast CT: A feasibility study

    International Nuclear Information System (INIS)

    Chen Lingyun; Shen Youtao; Lai, Chao-Jen; Han Tao; Zhong Yuncheng; Ge Shuaiping; Liu Xinming; Wang Tianpeng; Yang, Wei T.; Whitman, Gary J.; Shaw, Chris C.

    2009-01-01

    Purpose: In this study, the authors investigated the feasibility of a dual resolution volume-of-interest (VOI) cone beam breast CT technique and compared two implementation approaches in terms of dose saving and scatter reduction. Methods: With this technique, a lead VOI mask with an opening is inserted between the x-ray source and the breast to deliver x-ray exposure to the VOI while blocking x rays outside the VOI. A CCD detector is used to collect the high resolution projection data of the VOI. Low resolution cone beam CT (CBCT) images of the entire breast, acquired with a flat panel (FP) detector, were used to calculate the projection data outside the VOI with the ray-tracing reprojection method. The Feldkamp-Davis-Kress filtered backprojection algorithm was used to reconstruct the dual resolution 3D images. Breast phantoms with 180 μm and smaller microcalcifications (MCs) were imaged with both FP and FP-CCD dual resolution CBCT systems, respectively. Two approaches of implementing the dual resolution technique, breast-centered approach and VOI-centered approach, were investigated and evaluated for dose saving and scatter reduction with Monte Carlo simulation using a GEANT4 package. Results: The results showed that the breast-centered approach saved more breast absorbed dose than did VOI-centered approach with similar scatter reduction. The MCs in fatty breast phantom, which were invisible with FP CBCT scan, became visible with the FP-CCD dual resolution CBCT scan. Conclusions: These results indicate potential improvement of the image quality inside the VOI with reduced breast dose both inside and outside the VOI.

  8. Shallow surface depth profiling with atomic resolution

    International Nuclear Information System (INIS)

    Xi, J.; Dastoor, P.C.; King, B.V.; O'Connor, D.J.

    1999-01-01

    It is possible to derive atomic layer-by-layer composition depth profiles from popular electron spectroscopic techniques, such as X-ray photoelectron spectroscopy (XPS) or Auger electron spectroscopy (AES). When ion sputtering assisted AES or XPS is used, the changes that occur during the establishment of the steady state in the sputtering process make these techniques increasingly inaccurate for depths less than 3nm. Therefore non-destructive techniques of angle-resolved XPS (ARXPS) or AES (ARAES) have to be used in this case. In this paper several data processing algorithms have been used to extract the atomic resolved depth profiles of a shallow surface (down to 1nm) from ARXPS and ARAES data

  9. Employing Beam-Gas Interaction Vertices for Transverse Profile Measurements

    CERN Document Server

    Rihl, Mariana; Baglin, Vincent; Barschel, Colin; Bay, Aurelio; Blanc, Frederic; Bravin, Enrico; Bregliozzi, Giuseppe; Chritin, Nicolas; Dehning, Bernd; Ferro-Luzzi, Massimiliano; Gaspar, Clara; Gianì, Sebastiana; Giovannozzi, Massimo; Greim, Roman; Haefeli, Guido; Hopchev, Plamen; Jacobsson, Richard; Jensen, Lars; Jones, Owain Rhodri; Jurado, Nicolas; Kain, Verena; Karpinski, Waclaw; Kirn, Thomas; Kuhn, Maria; Luthi, Berengere; Magagnin, Paolo; Matev, Rosen; Nakada, Tatsuya; Neufeld, Niko; Panman, Jaap; Rakotomiaramanana, Barinjaka; Salustino Guimaraes, Valdir; Salvant, Benoit; Schael, Stefan; Schneider, Olivier; Schwering, Georg; Tobin, Mark; Veness, Raymond; Veyrat, Quentin; Vlachos, Sotiris; Wlochal, Michael; Xu, Zhirui; von Dratzig, Arndt

    2016-01-01

    Interactions of high-energy beam particles with residual gas offer a unique opportunity to measure the beam profile in a non-intrusive fashion. Such a method was successfully pioneered* at the LHCb experiment using a silicon microstrip vertex detector. During the recent Large Hadron Collider shutdown at CERN, a demonstrator Beam-Gas Vertexing system based on eight scintillating-fibre modules was designed**, constructed and installed on Ring 2 to be operated as a pure beam diagnostics device. The detector signals are read out and collected with LHCb-type front-end electronics and a DAQ system consisting of a CPU farm. Tracks and vertices will be reconstructed to obtain a beam profile in real time. Here, first commissioning results are reported. The advantages and potential for future applications of this technique are discussed.

  10. Non-destructive beam profile monitor at HIMAC

    International Nuclear Information System (INIS)

    Sato, S.; Araki, N.; Hosaka, M.

    1995-01-01

    Non-destructive profile monitors (NDPM), based on micro-channel plate (MCP), have been developed and installed in both the synchrotron ring and high-energy beam transport (HEBT) line at HIMAC. Beam test using these monitors have been carried out since April of 1995 to investigate a change of vertical beam size in synchrotron and a possibility of observing beam with high energy by one pass. In this paper the measurement system is mainly reported, and the preliminary results are also briefly presented. (author)

  11. A new beam profile monitor and time of flight system for CologneAMS

    Energy Technology Data Exchange (ETDEWEB)

    Pascovici, G. [CologneAMS, University of Cologne (Germany); Dewald, A., E-mail: dewald@ikp.uni-koeln.de [CologneAMS, University of Cologne (Germany); Institute of Nuclear Physics, University of Cologne (Germany); Heinze, S., E-mail: heinze@ikp.uni-koeln.de [CologneAMS, University of Cologne (Germany); Fink, L.; Mueller-Gatermann, C.; Schiffer, M.; Feuerstein, C. [CologneAMS, University of Cologne (Germany); Pfeiffer, M.; Jolie, J.; Thiel, S.; Zell, K.O.; Arnopolina, O. [Institute of Nuclear Physics, University of Cologne (Germany); Blanckenburg, F. von [GFZ, German Research Centre for Geosciences, Potsdam (Germany)

    2013-01-15

    A complex beam detector consisting of a high-resolution beam profile monitor (BPM) and a time of flight (TOF) spectrometer with tracking capabilities was designed especially for the special needs of the Cologne center for accelerator mass spectrometry (CologneAMS). The beam detector assembly is designed to match the beam specifications of the 6 MV Tandetron AMS setup and its data acquisition system. It will have a reconfigurable structure, either as a fast TOF subsystem with a ca. 10 cm{sup 2} equivalent active area, or as a more complex BPM-TOF detector with beam tracking capabilities and a larger active area (16 cm{sup 2}). The purpose of this detector is to suppress background during spectrometry of heavy ions (U, Cm, Pu, Am etc.) and to suppress isobaric interferences such as {sup 36}S in {sup 36}Cl spectra.

  12. R & D of a Gas-Filled RF Beam Profile Monitor for Intense Neutrino Beam Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Yonehara, K. [Fermilab; Backfish, M. [Fermilab; Moretti, A. [Fermilab; Tollestrup, A. V. [Fermilab; Watts, A. [Fermilab; Zwaska, R. M. [Fermilab; Abrams, R. [MUONS Inc., Batavia; Cummings, M. A.; Dudas, A. [MUONS Inc., Batavia; Johnson, R. P. [MUONS Inc., Batavia; Kazakevich, G. [MUONS Inc., Batavia; Neubauer, M. [MUONS Inc., Batavia; Liu, Q. [Case Western Reserve U.

    2017-05-01

    We report the R&D of a novel radiation-robust hadron beam profile monitor based on a gas-filled RF cavity for intense neutrino beam experiments. An equivalent RF circuit model was made and simulated to optimize the RF parameter in a wide beam intensity range. As a result, the maximum acceptable beam intensity in the monitor is significantly increased by using a low-quality factor RF cavity. The plan for the demonstration test is set up to prepare for future neutrino beam experiments.

  13. Preliminary results of spatially resolved ECR ion beam profile investigations

    International Nuclear Information System (INIS)

    Panitzsch, L.; Stalder, M.; Wimmer-Schweingruber, R.F.

    2012-01-01

    The profile of an ion beam produced in an Electron Cyclotron Resonance Ion Source (ECRIS) can vary greatly depending on the source settings and the ion-optical tuning. Strongly focussed ion beams form circular structures (hollow beams) as predicted by simulations and observed in experiments. Each of the rings is predicted to be dominated by ions with same or at least similar m/q-ratios due to ion-optical effects. To check this we performed a series of preliminary investigations to test the required tuning capabilities of our ion source. This includes beam focussing (A) and beam steering (B) using a 3D-movable extraction. Having tuned the source to deliver a beam of strongly focussed ions of different ion species and having steered this beam to match the transmittance area of the sector magnet we also recorded the ion charge state distribution of the strongly focussed beam profile at different, spatially limited positions (C). The preliminary results will be introduced within this paper: it appears that our 3D-movable extraction is very efficient to steer and to focus the beam strongly. The paper is followed by the slides of the presentation. (authors)

  14. An Electron Beam Profile Instrument Based on FBGs

    Directory of Open Access Journals (Sweden)

    Dan Sporea

    2014-08-01

    Full Text Available Along with the dose rate and the total irradiation dose measurements, the knowledge of the beam localization and the beam profile/energy distribution in the beam are parameters of interest for charged particle accelerator installations when they are used in scientific investigations, industrial applications or medical treatments. The transverse profile of the beam, its position, its centroid location, and its focus or flatness depend on the instrument operating conditions or on the beam exit setup. Proof-of-concept of a new type of charged particle beam diagnostics based on fiber Bragg gratings (FBGs was demonstrated. Its operating principle relies on the measurement of the peak wavelength changes for an array of FBG sensors as function of the temperature following the exposure to an electron beam. Periodically, the sensor irradiation is stopped and the FBG are force cooled to a reference temperature with which the temperature influencing each sensor during beam exposure is compared. Commercially available FBGs, and FBGs written in radiation resistant optical fibers, were tested under electron beam irradiation in order to study their possible use in this application.

  15. High intensity beam profile monitors for the LAMPF primary beam lines

    International Nuclear Information System (INIS)

    Hoffman, E.W.; Macek, R.J.; van Dyck, O.; Lee, D.; Harvey, A.; Bridge, J.; Cainet, J.

    1979-01-01

    Two types of beam profile monitors are in use at LAMPF to measure the properties of the 800 MeV, 500 μA proton beam external to the linac. Both types use secondary electron emission from a wire to produce a current signal proportional to the amount of proton beam that intercepts the wire. The wire scanner system uses a pair of orthogonal wires which are passed through the beam and the harp system uses two fixed planes of parallel wires. Most of the harps are not retractable and are exposed continuously to the primary beam. The high beam intensities available lead to a number of technical problems for instruments that intercept the beam or are close to primary beam targets. The thermal, electrical, radiation-damage, and material selection problems encountered, and some solutions which have been implemented are discussed

  16. Measurement of neutral beam power and beam profile distribution on DNB

    International Nuclear Information System (INIS)

    Liu Zhimin; Liu Sheng; Song Shihua; Han Xiaopu; Li Jun; Hu Chundong; Hu Liqun; Xie Jun

    2005-01-01

    The injection power of a diagnostic neutral beam (DNB) can be obtained with the thermocouple probe measurement system on the Hefei superconducting Tokamak-7 (HT-7). With the 49 kv, 6 A, 100 ms pulse charge of an acceleration electrode, a thermocouple probe measurement system with 13 thermocouples crossly distributed on a coppery heat target was used to measure the temperature rise of the target, and the maximum measured temperature rise was 14 degree C. And the neutral beam power of 160 kW and beam profile distribution was obtained by calculation. The total neutral beam power of 130 kW was also obtained by integral calculation with the temperature rise on the heat section board. The difference between the two means was analyzed. The experiment results shows that the method of heat section board with thermocouple probe is one of the effective ways to measure the beam power and beam profile distribution. (authors)

  17. Wide dynamic range beam profile monitor

    International Nuclear Information System (INIS)

    Lee, D.M.; Brown, D.; Hardekopf, R.; Bilskie, J.R.; van Dyck, O.B.V.

    1985-01-01

    An economical harp multiplexer system has been developed to achieve a wide dynamic range. The harp system incorporates a pneumatically actuated harp detector with ceramic boards and carbon wires; a high-sensitivity multiplexer packaged in a double-wide NIM module; and flat, shielded ribbon cable consisting of individual twisted pairs. The system multiplexes 30 wires in each of the x and y planes simultaneously and operates with or without computer control. The system has operated in beams of 100 nA to 1 mA, 1- to 120-Hz repetition rate, with a signal-to-noise ratio of greater than 10/1

  18. The characterization of beam profile by modification of electrode shape

    International Nuclear Information System (INIS)

    Lee, Chan Young; Lee, Jae Sang

    2010-01-01

    Ion sources have been used for variety of industrial application over the past few decades and our research group has been studied about high current and large dimension ion source to meet the requirement from beam user. For a mass production in industry, a wide beam divergence and a beam profile of a broadly Gaussian shape is very needed. Generally, the production process like roll-to-roll or in-line system is need one-meter in diameter, ±5% in uniformity. Therefore it is difficult to apply with present system like 0.3-meter in diameter, ±20% in uniformity and needed new type ion source. In this study, it is approached with modification of electrode grid shape without fabrication of new type ion source. We modified from parallel type to hemispherical type electrode grid to secure large dimension ion beam and were discussed with respect to beam profile calculated with IGUN code simulation. Also, we identified beam profile before and after modification of electrode grid system(cathode, Acelldecel grid) with measurement of faraday cup

  19. Wire Scanner Beam Profile Measurements for the LANSCE Facility

    Energy Technology Data Exchange (ETDEWEB)

    Gilpatrick, John D. [Los Alamos National Laboratory; Gruchalla, Michael E. [Los Alamos National Laboratory; Martinez, Derwin [Los Alamos National Laboratory; Pillai, Chandra [Los Alamos National Laboratory; Rodriguez Esparza, Sergio [Los Alamos National Laboratory; Sedillo, James Daniel [Los Alamos National Laboratory; Smith, Brian G. [Los Alamos National Laboratory

    2012-05-15

    The Los Alamos Neutron Science Center (LANSCE) is replacing beam profile measurement systems, commonly known as Wire Scanners (WS). Using the principal of secondary electron emission, the WS measurement system moves a wire or fiber across an impinging particle beam, sampling a projected transverse-beam distribution. Because existing WS actuators and electronic components are either no longer manufactured or home-built with antiquated parts, a new WS beam profile measurement is being designed, fabricated, and tested. The goals for these new WS's include using off-the-shelf components while eliminating antiquated components, providing quick operation while allowing for easy maintainability, and tolerating external radioactivation. The WS measurement system consists of beam line actuators, a cable plant, an electronics processor chassis, and software located both in the electronics chassis (National Instruments LabVIEW) and in the Central Control Room (EPICS-based client software). This WS measurement system will measure Hand H{sup +} LANSCE-facility beams and will also measure less common beams. This paper describes these WS measurement systems.

  20. Wire Scanner Beam Profile Measurements for the LANSCE Facility

    International Nuclear Information System (INIS)

    Gilpatrick, John D.; Gruchalla, Michael E.; Martinez, Derwin; Pillai, Chandra; Rodriguez Esparza, Sergio; Sedillo, James Daniel; Smith, Brian G.

    2012-01-01

    The Los Alamos Neutron Science Center (LANSCE) is replacing beam profile measurement systems, commonly known as Wire Scanners (WS). Using the principal of secondary electron emission, the WS measurement system moves a wire or fiber across an impinging particle beam, sampling a projected transverse-beam distribution. Because existing WS actuators and electronic components are either no longer manufactured or home-built with antiquated parts, a new WS beam profile measurement is being designed, fabricated, and tested. The goals for these new WS's include using off-the-shelf components while eliminating antiquated components, providing quick operation while allowing for easy maintainability, and tolerating external radioactivation. The WS measurement system consists of beam line actuators, a cable plant, an electronics processor chassis, and software located both in the electronics chassis (National Instruments LabVIEW) and in the Central Control Room (EPICS-based client software). This WS measurement system will measure Hand H + LANSCE-facility beams and will also measure less common beams. This paper describes these WS measurement systems.

  1. A webcam in Bayer-mode as a light beam profiler for the near infra-red.

    Science.gov (United States)

    Langer, Gregor; Hochreiner, Armin; Burgholzer, Peter; Berer, Thomas

    2013-05-01

    Beam profiles are commonly measured with complementary metal oxide semiconductors (CMOS) or charge coupled devices (CCD). The devices are fast and reliable but expensive. By making use of the fact that the Bayer-filter in commercial webcams is transparent in the near infra-red (>800 nm) and their CCD chips are sensitive up to about 1100 nm, we demonstrate a cheap and simple way to measure laser beam profiles with a resolution down to around ±1 μm, which is close to the resolution of the knife-edge technique.

  2. A laser-wire beam-energy and beam-profile monitor at the BNL linac

    Energy Technology Data Exchange (ETDEWEB)

    Connolly, R.; Degen, C.; DeSanto, L.; Meng, W.; Michnoff, R.; Minty, M.; Nayak, S.

    2011-03-28

    In 2009 a beam-energy monitor was installed in the high energy beam transport (HEBT) line at the Brookhaven National Lab linac. This device measures the energies of electrons stripped from the 40mA H{sup -} beam by background gas. Electrons are stripped by the 2.0x10{sup -7}torr residual gas at a rate of {approx}1.5x10{sup -8}/cm. Since beam electrons have the same velocities as beam protons, the beam proton energy is deduced by multiplying the electron energy by m{sub p}/m{sub e}=1836. A 183.6MeV H{sup -} beam produces 100keV electrons. In 2010 we installed an optics plates containing a laser and scanning optics to add beam-profile measurement capability via photodetachment. Our 100mJ/pulse, Q-switched laser neutralizes 70% of the beam during its 10ns pulse. This paper describes the upgrades to the detector and gives profile and energy measurements.

  3. Development of nanometer resolution C-Band radio frequency beam position monitors in the Final Focus Test Beam

    International Nuclear Information System (INIS)

    Slaton, T.; Mazaheri, G.

    1998-08-01

    Using a 47 GeV electron beam, the Final Focus Test Beam (FFTB) produces vertical spot sizes around 70 nm. These small beam sizes introduce an excellent opportunity to develop and test high resolution Radio Frequency Beam Position Monitors (RF-BPMs). These BPMs are designed to measure pulse to pulse beam motion (jitter) at a theoretical resolution of approximately 1 nm. The beam induces a TM 110 mode with an amplitude linearly proportional to its charge and displacement from the BPM's (cylindrical cavity) axis. The C-band (5,712 MHz) TM 110 signal is processed and converted into beam position for use by the Stanford Linear Collider (SLC) control system. Presented are the experimental procedures, acquisition, and analysis of data demonstrating resolution of jitter near 25 nm. With the design of future e + e - linear colliders requiring spot sizes close to 3 nm, understanding and developing RF-BPMs will be essential in resolving and controlling jitter

  4. 2D electron density profile measurement in tokamak by laser-accelerated ion-beam probe.

    Science.gov (United States)

    Chen, Y H; Yang, X Y; Lin, C; Wang, L; Xu, M; Wang, X G; Xiao, C J

    2014-11-01

    A new concept of Heavy Ion Beam Probe (HIBP) diagnostic has been proposed, of which the key is to replace the electrostatic accelerator of traditional HIBP by a laser-driven ion accelerator. Due to the large energy spread of ions, the laser-accelerated HIBP can measure the two-dimensional (2D) electron density profile of tokamak plasma. In a preliminary simulation, a 2D density profile was reconstructed with a spatial resolution of about 2 cm, and with the error below 15% in the core region. Diagnostics of 2D density fluctuation is also discussed.

  5. Dual beam organic depth profiling using large argon cluster ion beams

    Science.gov (United States)

    Holzweber, M; Shard, AG; Jungnickel, H; Luch, A; Unger, WES

    2014-01-01

    Argon cluster sputtering of an organic multilayer reference material consisting of two organic components, 4,4′-bis[N-(1-naphthyl-1-)-N-phenyl- amino]-biphenyl (NPB) and aluminium tris-(8-hydroxyquinolate) (Alq3), materials commonly used in organic light-emitting diodes industry, was carried out using time-of-flight SIMS in dual beam mode. The sample used in this study consists of a ∽400-nm-thick NPB matrix with 3-nm marker layers of Alq3 at depth of ∽50, 100, 200 and 300 nm. Argon cluster sputtering provides a constant sputter yield throughout the depth profiles, and the sputter yield volumes and depth resolution are presented for Ar-cluster sizes of 630, 820, 1000, 1250 and 1660 atoms at a kinetic energy of 2.5 keV. The effect of cluster size in this material and over this range is shown to be negligible. © 2014 The Authors. Surface and Interface Analysis published by John Wiley & Sons Ltd. PMID:25892830

  6. Sparse Representation Denoising for Radar High Resolution Range Profiling

    Directory of Open Access Journals (Sweden)

    Min Li

    2014-01-01

    Full Text Available Radar high resolution range profile has attracted considerable attention in radar automatic target recognition. In practice, radar return is usually contaminated by noise, which results in profile distortion and recognition performance degradation. To deal with this problem, in this paper, a novel denoising method based on sparse representation is proposed to remove the Gaussian white additive noise. The return is sparsely described in the Fourier redundant dictionary and the denoising problem is described as a sparse representation model. Noise level of the return, which is crucial to the denoising performance but often unknown, is estimated by performing subspace method on the sliding subsequence correlation matrix. Sliding window process enables noise level estimation using only one observation sequence, not only guaranteeing estimation efficiency but also avoiding the influence of profile time-shift sensitivity. Experimental results show that the proposed method can effectively improve the signal-to-noise ratio of the return, leading to a high-quality profile.

  7. Gaussian beam profile shaping apparatus, method therefore and evaluation thereof

    International Nuclear Information System (INIS)

    Dickey, F.M.; Holswade, S.C.; Romero, L.A.

    1999-01-01

    A method and apparatus maps a Gaussian beam into a beam with a uniform irradiance profile by exploiting the Fourier transform properties of lenses. A phase element imparts a design phase onto an input beam and the output optical field from a lens is then the Fourier transform of the input beam and the phase function from the phase element. The phase element is selected in accordance with a dimensionless parameter which is dependent upon the radius of the incoming beam, the desired spot shape, the focal length of the lens and the wavelength of the input beam. This dimensionless parameter can also be used to evaluate the quality of a system. In order to control the radius of the incoming beam, optics such as a telescope can be employed. The size of the target spot and the focal length can be altered by exchanging the transform lens, but the dimensionless parameter will remain the same. The quality of the system, and hence the value of the dimensionless parameter, can be altered by exchanging the phase element. The dimensionless parameter provides design guidance, system evaluation, and indication as to how to improve a given system. 27 figs

  8. A multiwire secondary emission profile monitor for small emittance beams

    International Nuclear Information System (INIS)

    Chehab, R.; Bonnard, J.; Humbert, G.; Leblond, B.; Saury, J.L.

    1985-01-01

    A secondary emission monitor using two multiwire grids separated by a positively biased collector has been constructed and tested with a 1 GeV electron beam at the Orsay Linac. The monitor installed just before the electron-positron converter has 8 gold-plated-tungsten wires of 0.1 mm diameter equally spaced 0.2 mm apart in each plane. Each wire is connected with an integrator using a low-bias current operational amplifier. The wire planes and the collector are moved into the beam by a stepping motor : that allows beam-position verification. We measured narrow profiles for 1 Amp peak current pulses of 30 nanoseconds width. Profiles are displayed on a scope and allow emittance determination by the three gradient method. Such a monitor is very useful to control the electron beam position and dimensions on the converter, because the positron source dimensions are rather bigger than those of the incident beam and the geometrical acceptance of the positron Linac is limited

  9. Beam profiles in the nonwedged direction for dynamic wedges

    International Nuclear Information System (INIS)

    Lydon, J.M.; Rykers, K.L.

    1996-01-01

    One feature of the dynamic wedge is the improved flatness of the beam profile in the nonwedged direction when compared to fixed wedges. Profiles in the nonwedged direction for fixed wedges show a fall-off in dose away from the central axis when compared to the open field profile. This study will show that there is no significant difference between open field profiles and nonwedged direction profiles for dynamically wedged beams. The implications are that the dynamic wedge offers an improved dose distribution in the nonwedged direction that can be modelled by approximating the dynamically wedged field to an open field. This is possible as both the profiles and depth doses of the dynamically wedged fields match those of the open fields, if normalized to d max of the same field size. For treatment planning purposes the effective wedge factor (EWF) provides a normalization factor for the open field depth dose data set. Data will be presented to demonstrate that the EWF shows relatively little variation with depth and can be treated as being independent of field size in the nonwedged direction. (author)

  10. PROFIL-360 high resolution steam generator tube profilometry system

    International Nuclear Information System (INIS)

    Glass, S.W.

    1985-01-01

    A high-resolution profilometry system, PROFIL 360, has been developed to assess the condition of steam generator tubes and rapidly produce the data to evaluate the potential for developing in-service leaks. The probe has an electromechanical sensor in a rotating head. This technique has been demonstrated in the field, saving tubes that would have been plugged with the go-gauge criterion and indicating plugging other high-risk candidates that might otherwise not have been removed from service

  11. Profil-360 high resolution steam generator tube profilometry system

    International Nuclear Information System (INIS)

    Glass, S.W.

    1985-01-01

    A high-resolution profilometry system, PROFIL 360, has been developed to assess the condition of steam generator tubes and rapidly produce the data to evaluate the potential for developing in-service leaks. The probe has an electromechanical sensor in a rotating head. This technique has been demonstrated in the field, saving tubes that would have been plugged with the go-gauge criterion and indicating plugging other high-risk candidates that might otherwise not have been removed from service

  12. A beam-profile monitor for the BNL Accelerator Test Facility (ATF)

    International Nuclear Information System (INIS)

    Russell, D.P.; McDonald, K.T.

    1989-01-01

    A beam-profile monitor has been designed to diagnose the 5-MeV high-brightness electron beam from the rf gun of the BNL Accelerator Test Facility (ATF). The monitor consists of a phosphor screen viewed by a CCD camera. The video images are digitized and stored by a framegrabber and analyzed by an IBM PC-AT to extract the emittance. Details of the hardware configuration are presented, along with the spatial resolution of the system measured as a function of phosphor-screen thickness. The strategies which will be used to measure the transverse and longitudinal emittances are briefly mentioned. The system should be capable of measuring a transverse geometric emittance of around 1 mm-mrad, as will be typical of the ATF beam. 6 refs., 2 figs

  13. A gamma beam profile imager for ELI-NP Gamma Beam System

    Science.gov (United States)

    Cardarelli, P.; Paternò, G.; Di Domenico, G.; Consoli, E.; Marziani, M.; Andreotti, M.; Evangelisti, F.; Squerzanti, S.; Gambaccini, M.; Albergo, S.; Cappello, G.; Tricomi, A.; Veltri, M.; Adriani, O.; Borgheresi, R.; Graziani, G.; Passaleva, G.; Serban, A.; Starodubtsev, O.; Variola, A.; Palumbo, L.

    2018-06-01

    The Gamma Beam System of ELI-Nuclear Physics is a high brilliance monochromatic gamma source based on the inverse Compton interaction between an intense high power laser and a bright electron beam with tunable energy. The source, currently being assembled in Magurele (Romania), is designed to provide a beam with tunable average energy ranging from 0.2 to 19.5 MeV, rms energy bandwidth down to 0.5% and flux of about 108 photons/s. The system includes a set of detectors for the diagnostic and complete characterization of the gamma beam. To evaluate the spatial distribution of the beam a gamma beam profile imager is required. For this purpose, a detector based on a scintillator target coupled to a CCD camera was designed and a prototype was tested at INFN-Ferrara laboratories. A set of analytical calculations and Monte Carlo simulations were carried out to optimize the imager design and evaluate the performance expected with ELI-NP gamma beam. In this work the design of the imager is described in detail, as well as the simulation tools used and the results obtained. The simulation parameters were tuned and cross-checked with the experimental measurements carried out on the assembled prototype using the beam from an x-ray tube.

  14. Emittance compensation with dynamically optimized photoelectron beam profiles

    Energy Technology Data Exchange (ETDEWEB)

    Rosenzweig, J.B. [Department of Physics and Astronomy, UCLA, 405 Hilgard Avenue, Los Angeles, CA 90095 (United States)]. E-mail: rosen@physics.ucla.edu; Cook, A.M. [Department of Physics and Astronomy, UCLA, 405 Hilgard Avenue, Los Angeles, CA 90095 (United States); England, R.J. [Department of Physics and Astronomy, UCLA, 405 Hilgard Avenue, Los Angeles, CA 90095 (United States); Dunning, M. [Department of Physics and Astronomy, UCLA, 405 Hilgard Avenue, Los Angeles, CA 90095 (United States); Anderson, S.G. [Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA 94550 (United States); Ferrario, Massimo [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionale di Frascati, Via E. Fermi 41, Frascati, Rome (Italy)

    2006-02-01

    Much of the theory and experimentation concerning creation of a high-brightness electron beam from a photocathode, and then applying emittance compensation techniques, assumes that one must strive for a uniform density electron beam, having a cylindrical shape. On the other hand, this shape has large nonlinearities in the space-charge field profiles near the beam's longitudinal extrema. These nonlinearities are known to produce both transverse and longitudinal emittance growth. On the other hand, it has recently been shown by Luiten that by illuminating the cathode with an ultra-short laser pulse of appropriate transverse profile, a uniform density, ellipsoidally shaped bunch is dynamically formed, which then has linear space-charge fields in all dimensions inside of the bunch. We study here this process, and its marriage to the standard emittance compensation scenario that is implemented in most recent photoinjectors. It is seen that the two processes are compatible, with simulations indicating a very high brightness beam can be obtained. The robustness of this scheme to systematic errors is examined. Prospects for experimental tests of this scheme are discussed.

  15. Emittance compensation with dynamically optimized photoelectron beam profiles

    International Nuclear Information System (INIS)

    Rosenzweig, J.B.; Cook, A.M.; England, R.J.; Dunning, M.; Anderson, S.G.; Ferrario, Massimo

    2006-01-01

    Much of the theory and experimentation concerning creation of a high-brightness electron beam from a photocathode, and then applying emittance compensation techniques, assumes that one must strive for a uniform density electron beam, having a cylindrical shape. On the other hand, this shape has large nonlinearities in the space-charge field profiles near the beam's longitudinal extrema. These nonlinearities are known to produce both transverse and longitudinal emittance growth. On the other hand, it has recently been shown by Luiten that by illuminating the cathode with an ultra-short laser pulse of appropriate transverse profile, a uniform density, ellipsoidally shaped bunch is dynamically formed, which then has linear space-charge fields in all dimensions inside of the bunch. We study here this process, and its marriage to the standard emittance compensation scenario that is implemented in most recent photoinjectors. It is seen that the two processes are compatible, with simulations indicating a very high brightness beam can be obtained. The robustness of this scheme to systematic errors is examined. Prospects for experimental tests of this scheme are discussed

  16. Profile distortion by beam space-charge in Ionization Profile Monitors

    CERN Document Server

    Vilsmeier, D; Wettig, T

    Measuring the transverse beam size in the Large Hadron Collider by using Ionization Profile Monitors is a difficult task for energies above injection during the energy ramp from 450 GeV to 6.5TeV. The beam size decreases from around 1mm to 200um and the brightness of the beam is high enough to destroy the structure of any form of interacting matter. While the electron trajectories are confined by an external electro-magnetic field which forces the electrons accordingly on helix paths with certain gyroradii, this gyration is heavily increased under the influence of the electric field of the beam. Smaller beam sizes, which go hand in hand with increased bunch electric fields, lead to larger gyroradii of the ionized electrons, which results in strongly distorted profiles. In addition, this distortion becomes more visible for smaller beam sizes as the extent of gyration grows compared to the actual beam size. Depending on the initial momentum distribution of the electrons, emerging from the ionization process wit...

  17. Beam-transport system for high-resolution heavy-ion spectroscopy

    International Nuclear Information System (INIS)

    Roussel, P.; Kashy, E.

    1980-01-01

    A method is given to adjust a beam-transport system to the requirements of high-energy resolution heavy-ion spectroscopy. The results of a test experiment performed on a MP tandem with a 12 C beam are shown. A drastic improvement in energy resolution is obtained for a kinematical factor K=1/p dp/dtheta=0.12 [fr

  18. Three-beam aerosol backscatter correlation lidar for wind profiling

    Science.gov (United States)

    Prasad, Narasimha S.; Radhakrishnan Mylapore, Anand

    2017-03-01

    The development of a three-beam aerosol backscatter correlation (ABC) light detection and ranging (lidar) to measure wind characteristics for wake vortex and plume tracking applications is discussed. This is a direct detection elastic lidar that uses three laser transceivers, operating at 1030-nm wavelength with ˜10-kHz pulse repetition frequency and nanosec class pulse widths, to directly obtain three components of wind velocities. By tracking the motion of aerosol structures along and between three near-parallel laser beams, three-component wind speed profiles along the field-of-view of laser beams are obtained. With three 8-in. transceiver modules, placed in a near-parallel configuration on a two-axis pan-tilt scanner, the lidar measures wind speeds up to 2 km away. Optical flow algorithms have been adapted to obtain the movement of aerosol structures between the beams. Aerosol density fluctuations are cross-correlated between successive scans to obtain the displacements of the aerosol features along the three axes. Using the range resolved elastic backscatter data from each laser beam, which is scanned over the volume of interest, a three-dimensional map of aerosol density can be generated in a short time span. The performance of the ABC wind lidar prototype, validated using sonic anemometer measurements, is discussed.

  19. Analytical & Experimental Study of Radio Frequency Cavity Beam Profile Monitor

    Energy Technology Data Exchange (ETDEWEB)

    Balcazar, Mario D. [Fermilab; Yonehara, Katsuya [Fermilab

    2017-10-22

    The purpose of this analytical and experimental study is multifold: 1) To explore a new, radiation-robust, hadron beam profile monitor for intense neutrino beam applications; 2) To test, demonstrate, and develop a novel gas-filled Radio-Frequency (RF) cavity to use in this monitoring system. Within this context, the first section of the study analyzes the beam distribution across the hadron monitor as well as the ion-production rate inside the RF cavity. Furthermore a more effecient pixel configuration across the hadron monitor is proposed to provide higher sensitivity to changes in beam displacement. Finally, the results of a benchtop test of the tunable quality factor RF cavity will be presented. The proposed hadron monitor configuration consists of a circular array of RF cavities located at a radial distance of 7cm { corresponding to the standard deviation of the beam due to scatering { and a gas-filled RF cavity with a quality factor in the range 400 - 800.

  20. Influence of total beam current on HRTEM image resolution in differentially pumped ETEM with nitrogen gas

    International Nuclear Information System (INIS)

    Bright, A.N.; Yoshida, K.; Tanaka, N.

    2013-01-01

    Environmental transmission electron microscopy (ETEM) enables the study of catalytic and other reaction processes as they occur with Angstrom-level resolution. The microscope used is a dedicated ETEM (Titan ETEM, FEI Company) with a differential pumping vacuum system and apertures, allowing aberration corrected high-resolution transmission electron microscopy (HRTEM) imaging to be performed with gas pressures up to 20 mbar in the sample area and with significant advantages over membrane-type E-cell holders. The effect on image resolution of varying the nitrogen gas pressure, electron beam current density and total beam current were measured using information limit (Young's fringes) on a standard cross grating sample and from silicon crystal lattice imaging. As expected, increasing gas pressure causes a decrease in HRTEM image resolution. However, the total electron beam current also causes big changes in the image resolution (lower beam current giving better resolution), whereas varying the beam current density has almost no effect on resolution, a result that has not been reported previously. This behavior is seen even with zero-loss filtered imaging, which we believe shows that the drop in resolution is caused by elastic scattering at gas ions created by the incident electron beam. Suitable conditions for acquiring high resolution images in a gas environment are discussed. Lattice images at nitrogen pressures up to 16 mbar are shown, with 0.12 nm information transfer at 4 mbar. -- Highlights: ► ETEM images with point resolution of 0.12 nm in 4 mbar of nitrogen gas. ► Clear Si lattice imaging with 16 mbar of nitrogen gas. ► ETEM image resolution in gas can be much improved by decreasing total beam current. ► Beam current density (beam convergence) has no effect on the image resolution.

  1. Electron beam based transversal profile measurements of intense ion beams; Elektronenstrahl-Diagnostik zur Bestimmung vom transversalen Profil intensiver Ionenstrahlen

    Energy Technology Data Exchange (ETDEWEB)

    El Moussati, Said

    2014-11-03

    A non-invasive diagnostic method for the experimental determination of the transverse profile of an intense ion beam has been developed and investigated theoretically as well as experimentally within the framework of the present work. The method is based on the deflection of electrons when passing the electromagnetic field of an ion beam. To achieve this an electron beam is employed with a specifically prepared transversal profile. This distinguish this method from similar ones which use thin electron beams for scanning the electromagnetic field [Roy et al. 2005; Blockland10]. The diagnostic method presented in this work will be subsequently called ''Electron-Beam-Imaging'' (EBI). First of all the influence of the electromagnetic field of the ion beam on the electrons has been theoretically analyzed. It was found that the magnetic field causes only a shift of the electrons along the ion beam axis, while the electric field only causes a shift in a plane transverse to the ion beam. Moreover, in the non-relativistic case the magnetic force is significantly smaller than the Coulomb one and the electrons suffer due to the magnetic field just a shift and continue to move parallel to their initial trajectory. Under the influence of the electric field, the electrons move away from the ion beam axis, their resulting trajectory shows a specific angle compared to the original direction. This deflection angle practically depends just on the electric field of the ion beam. Thus the magnetic field has been neglected when analysing the experimental data. The theoretical model provides a relationship between the deflection angle of the electrons and the charge distribution in the cross section of the ion beam. The model however only can be applied for small deflection angles. This implies a relationship between the line-charge density of the ion beam and the initial kinetic energy of the electrons. Numerical investigations have been carried out to clarify the

  2. Focused ion-beam line profiles: A study of some factors affecting beam broadening

    International Nuclear Information System (INIS)

    Templeton, I.M.; Champion, H.G.

    1995-01-01

    The current--density profile of a focused ion beam (FIB) has a central peak accompanied by broader ''wings'' that, while unimportant in lithographic applications, can lead to unwanted effects during an implantation operation. The origin of the wings, and hence the best way to minimize them, is not clear and needs further study. We have measured the line profiles of several of the ions available in our FIB machine as a function of a number of variables, under ultrahigh vacuum (UHV) conditions. No effects are observed from changes in emission current or deliberate defocusing of the objective lens. There are some changes with beam aperture and/or current, but the biggest differences seem to be associated with a change of source type and hence, possibly, with a change in the source/extractor configuration or in the alloy and the emission process. The wing amplitudes are appreciably lower than many previously observed, and their profiles, at least for the lighter ions studied (Be ++ , Be + , and B + ), are Gaussian rather than exponential. It seems possible that our UHV conditions may have eliminated a scattering mechanism responsible for the larger, exponential wings previously observed. The corresponding beam and rectangle-edge profiles have been calculated. copyright 1995 American Vacuum Society

  3. Determination of the meniscus shape of a negative ion beam from an experimentally obtained beam profile

    Science.gov (United States)

    Ichikawa, M.; Kojima, A.; Chitarin, G.; Agostinetti, P.; Aprile, D.; Baltador, C.; Barbisan, M.; Delogu, R.; Hiratsuka, J.; Marconato, N.; Nishikiori, R.; Pimazzoni, A.; Sartori, E.; Serianni, G.; Tobari, H.; Umeda, N.; Veltri, P.; Watanabe, K.; Yoshida, M.; Antoni, V.; Kashiwagi, M.

    2017-08-01

    In order to understand the physics mechanism of a negative ion extraction in negative ion sources, an emission surface of the negative ions around an aperture at a plasma grid, so-called a meniscus, has been analyzed by an inverse calculation of the negative ion trajectory in a two dimensional beam analysis code. In this method, the meniscus is defined as the final position of the negative ion trajectories which are inversely calculated from the measured beam profile to the plasma grid. In a case of the volume-produced negative ions, the calculated meniscus by the inverse calculation was similar to that obtained in conventional beam simulation codes for positive ion extractions such as BEAMORBT and SLACCAD. The negative ion current density was uniform along the meniscus. This indicates that the negative ions produced in the plasma are transported to the plasma grid uniformly as considered in the transportation of the positive ions. However, in a surface production case of negative ions, where the negative ions are generated near the plasma grid with lower work function by seeding cesium, the current density in the peripheral region of the meniscus close to the plasma grid surface was estimated to be 2 times larger than the center region, which suggested that the extraction process of the surface-produced negative ions was much different with that for the positive ions. Because this non-uniform profile of the current density made the meniscus shape strongly concave, the beam extracted from the peripheral region could have a large divergence angle, which might be one of origins of so-called beam halo. This is the first results of the determination of the meniscus based on the experiment, which is useful to improve the prediction of the meniscus shape and heat loads based on the beam trajectories including beam halo.

  4. Flying wire beam profile monitor at the J-PARC MR

    International Nuclear Information System (INIS)

    Igarashi, Susumu; Arakawa, Dai; Hashimoto, Yoshinori; Teshima, Masaki; Toyama, Takeshi; Hanamura, Kotoku

    2008-01-01

    A flying wire beam profile monitor has been assembled and installed at the main ring of the Japan Proton Accelerator Research Complex. The monitor is to measure the horizontal beam profile using a carbon fiber of 7 μmφ. The fiber crosses the beam with the speed of 10 m/s. Secondary particles from the beam-wire scattering is detected using a scintillation counter. The scintillator signal as a function of the wire position is to be reconstructed as a beam profile. The high scanning speed and the minimum material are necessary for the accurate beam profile measurement. The monitor has been operated in the beam commissioning run of the main ring. The beam profile data have been successfully acquired after the reduction of the beam background. (author)

  5. K-band EPR dosimetry: small-field beam profile determination with miniature alanine dosimeter

    International Nuclear Information System (INIS)

    Chen, Felipe; Graeff, Carlos F.O.; Baffa, Oswaldo

    2005-01-01

    The use of small-size alanine dosimeters presents a challenge because the signal intensity is less than the spectrometer sensitivity. K-band (24 GHz) EPR spectrometer seems to be a good compromise between size and sensitivity of the sample. Miniature alanine pellets were evaluated for small-field radiation dosimetry. Dosimeters of DL-alanine/PVC with dimensions of 1.5 mm diameter and 2.5 mm length with 5 mg mass were developed. These dosimeters were irradiated with 10 MV X-rays in the dose range 0.05-60 Gy and the first harmonic (1 h) spectra were recorded. Microwave power, frequency and amplitude of modulation were optimized to obtain the best signal-to-noise ratio (S/N). For beam profile determination, a group of 25 dosimeters were placed in an acrylic device with dimensions of (7.5x2.5x1) cm 3 and irradiated with a (3x3) cm 2 10 MV X-rays beam field size. The dose at the central region of the beam was 20 Gy at a depth of 2.2 cm (build up for acrylic). The acrylic device was oriented perpendicular to the beam axis and to the gantry rotation axis. For the purposes of comparison of the spatial resolution, the beam profile was also determined with a radiographic film and 2 mm aperture optical densitometer; in this case the dose was 1 cGy. The results showed a similar spatial resolution for both types of dosimeters. The dispersion in dose reading was larger for alanine in comparison with the film, but alanine dosimeters can be read faster and more directly than film over a wide dose range

  6. Influence of total beam current on HRTEM image resolution in differentially pumped ETEM with nitrogen gas.

    Science.gov (United States)

    Bright, A N; Yoshida, K; Tanaka, N

    2013-01-01

    Environmental transmission electron microscopy (ETEM) enables the study of catalytic and other reaction processes as they occur with Angstrom-level resolution. The microscope used is a dedicated ETEM (Titan ETEM, FEI Company) with a differential pumping vacuum system and apertures, allowing aberration corrected high-resolution transmission electron microscopy (HRTEM) imaging to be performed with gas pressures up to 20 mbar in the sample area and with significant advantages over membrane-type E-cell holders. The effect on image resolution of varying the nitrogen gas pressure, electron beam current density and total beam current were measured using information limit (Young's fringes) on a standard cross grating sample and from silicon crystal lattice imaging. As expected, increasing gas pressure causes a decrease in HRTEM image resolution. However, the total electron beam current also causes big changes in the image resolution (lower beam current giving better resolution), whereas varying the beam current density has almost no effect on resolution, a result that has not been reported previously. This behavior is seen even with zero-loss filtered imaging, which we believe shows that the drop in resolution is caused by elastic scattering at gas ions created by the incident electron beam. Suitable conditions for acquiring high resolution images in a gas environment are discussed. Lattice images at nitrogen pressures up to 16 mbar are shown, with 0.12 nm information transfer at 4 mbar. Copyright © 2012 Elsevier B.V. All rights reserved.

  7. A real-time intercepting beam-profile monitor for a medical cyclotron

    Energy Technology Data Exchange (ETDEWEB)

    Hendriks, C.; Uittenbosch, T.; Cameron, D.; Kellogg, S.; Gray, D.; Buckley, K.; Schaffer, P.; Verzilov, V.; Hoehr, C. [TRIUMF, 4004 Wesbrook Mall, Vancouver, British Columbia V6T 2A3 (Canada)

    2013-11-15

    There is a lack of real-time continuous beam-diagnostic tools for medical cyclotrons due to high power deposition during proton irradiation. To overcome this limitation, we have developed a profile monitor that is capable of providing continuous feedback about beam shape and current in real time while it is inserted in the beam path. This enables users to optimize the beam profile and observe fluctuations in the beam over time with periodic insertion of the monitor.

  8. The Beam Profile Monitoring System for the CERN IRRAD Proton Facility

    CERN Document Server

    Ravotti, F; Glaser, M; Matli, E; Pezzullo, G; Gan, K K; Kagan, H; Smith, S; Warner, J D

    2017-01-01

    GeV/c proton beam is used. During beam steering and irradiation, the intensity and the transverse profile of the proton beam are monitored online with custom-made Beam Profile Monitor (BPM) devices. In this work, we present the design and the architecture of the IRRAD BPM system, some results on its performance with the proton beam, as well as its planned grades.

  9. Development of a reusable beam profile analyzer for laser accelerated proton beams

    Energy Technology Data Exchange (ETDEWEB)

    Frydrych, Simon; Busold, Simon; Deppert, Oliver; Roth, Markus [Technische Univ. Darmstadt (Germany). Inst. fuer Kernphysik

    2013-07-01

    At the GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, proton beams are generated with the PHELIX laser system through target normal sheath acceleration (TNSA). Within 1 ps, 10{sup 13} protons are produced with an exponential energy spectrum up to 50 MeV. For characterisation, the spatial beam profile is currently detected by a stack of radiochromatic films (RCF). These are blued depending on the beam intensity. One disadvantage of RCFs is its one-time usability. Therefore, they shall be replaced by a scintillator array. To ensure the longest possible shelf life of this new detector, the scintillator material used must be very robust against radiation damage. Also a point of current research is the maximal amount of particles, which can be detected separately.

  10. Depth profiling of boron implanted silicon by positron beam

    International Nuclear Information System (INIS)

    Oevuenc, S.

    2004-01-01

    Positron depth profiling analyses of low energy implants of silicon aim to observe tbe structure and density of the vacancies generating by implantation and the effect of annealing. This work present the results to several set of data starting S and W parameters. Boron implanted Silicon samples with different implantation energies,20,22,24,and 26 keV are analyzed by Slow positron beam (0-40 keV and 10 5 e + /s )(Variable Energy Positron) at the Positron Centre Delf-HOLLAND

  11. Beam profile diagnostics system for SDUV-FEL

    International Nuclear Information System (INIS)

    Xu Yichao; Han Lifeng; Chen Yongzhong

    2010-01-01

    A new beam profile diagnostics system for Shanghai Deep Ultraviolet Free Electron Laser (SDUV-FEL) has been developed based on industrial Ethernet, with good versatility and scalability. The system includes three major subsystems for image acquisition,pneumatic control and stepper motor control, respectively. Virtual instrument technology is adopted to drive the devices, and to develop the measurement software. In this paper,we describe the system structure, and its hardware and software design. The results of system commissioning are given as well. As an important diagnostic tool and data acquisition method, the system has been successfully applied to the measurement and control of the SDUV-FEL.(authors)

  12. Radiographic film dosimetry of proton beams for depth‐dose constancy check and beam profile measurement

    Science.gov (United States)

    Teran, Anthony; Ghebremedhin, Abiel; Johnson, Matt; Patyal, Baldev

    2015-01-01

    Radiographic film dosimetry suffers from its energy dependence in proton dosimetry. This study sought to develop a method of measuring proton beams by the film and to evaluate film response to proton beams for the constancy check of depth dose (DD). It also evaluated the film for profile measurements. To achieve this goal, from DDs measured by film and ion chamber (IC), calibration factors (ratios of dose measured by IC to film responses) as a function of depth in a phantom were obtained. These factors imply variable slopes (with proton energy and depth) of linear characteristic curves that relate film response to dose. We derived a calibration method that enables utilization of the factors for acquisition of dose from film density measured at later dates by adapting to a potentially altered processor condition. To test this model, the characteristic curve was obtained by using EDR2 film and in‐phantom film dosimetry in parallel with a 149.65 MeV proton beam, using the method. An additional validation of the model was performed by concurrent film and IC measurement perpendicular to the beam at various depths. Beam profile measurements by the film were also evaluated at the center of beam modulation. In order to interpret and ascertain the film dosimetry, Monte Carlos simulation of the beam was performed, calculating the proton fluence spectrum along depths and off‐axis distances. By multiplying respective stopping powers to the spectrum, doses to film and water were calculated. The ratio of film dose to water dose was evaluated. Results are as follows. The characteristic curve proved the assumed linearity. The measured DD approached that of IC, but near the end of the spread‐out Bragg peak (SOBP), a spurious peak was observed due to the mismatch of distal edge between the calibration and measurement films. The width of SOBP and the proximal edge were both reproducible within a maximum of 5 mm; the distal edge was reproducible within 1 mm. At 5 cm depth, the

  13. Development of nanometer resolution C-Band radio frequency beam position monitors in the Final Focus Test Beam

    Energy Technology Data Exchange (ETDEWEB)

    Slaton, T.; Mazaheri, G. [Stanford Univ., CA (US). Stanford Linear Accelerator Center; Shintake, T. [National Lab. for High Energy Physics, Tsukuba, Ibaraki (Japan)

    1998-08-01

    Using a 47 GeV electron beam, the Final Focus Test Beam (FFTB) produces vertical spot sizes around 70 nm. These small beam sizes introduce an excellent opportunity to develop and test high resolution Radio Frequency Beam Position Monitors (RF-BPMs). These BPMs are designed to measure pulse to pulse beam motion (jitter) at a theoretical resolution of approximately 1 nm. The beam induces a TM{sub 110} mode with an amplitude linearly proportional to its charge and displacement from the BPM's (cylindrical cavity) axis. The C-band (5,712 MHz) TM{sub 110} signal is processed and converted into beam position for use by the Stanford Linear Collider (SLC) control system. Presented are the experimental procedures, acquisition, and analysis of data demonstrating resolution of jitter near 25 nm. With the design of future e{sup +}e{sup -} linear colliders requiring spot sizes close to 3 nm, understanding and developing RF-BPMs will be essential in resolving and controlling jitter.

  14. High-resolution humidity profiles retrieved from wind profiler radar measurements

    Science.gov (United States)

    Saïd, Frédérique; Campistron, Bernard; Di Girolamo, Paolo

    2018-03-01

    The retrieval of humidity profiles from wind profiler radars has already been documented in the past 30 years and is known to be neither as straightforward and nor as robust as the retrieval of the wind velocity. The main constraint to retrieve the humidity profile is the necessity to combine measurements from the wind profiler and additional measurements (such as observations from radiosoundings at a coarser time resolution). Furthermore, the method relies on some assumptions and simplifications that restrict the scope of its application. The first objective of this paper is to identify the obstacles and limitations and solve them, or at least define the field of applicability. To improve the method, we propose using the radar capacity to detect transition levels, such as the top level of the boundary layer, marked by a maximum in the radar reflectivity. This forces the humidity profile from the free troposphere and from the boundary layer to coincide at this level, after an optimization of the calibration coefficients, and reduces the error. The resulting mean bias affecting the specific humidity profile never exceeds 0.25 g kg-1. The second objective is to explore the capability of the algorithm to retrieve the humidity vertical profiles for an operational purpose by comparing the results with observations from a Raman lidar.

  15. Analysis of the Influence of Fibre Diameter on Wirescanner Beam Profile Measurements

    CERN Document Server

    King, Quentin

    1988-01-01

    It is often important to be able to measure beam profiles in regions where the beam size is very small. Following concern that the profile measurement might be affected by having a beam size of the same order as the diameter of the wirescanner fibre, the effect was analysed numerically, and the results are presented.

  16. A scintillating fibre-based profiler for low intensity ion beams

    Energy Technology Data Exchange (ETDEWEB)

    Finocchiaro, P. [Istituto Nazionale di Fisica Nucleare, Catania (Italy); Amato, A. [Istituto Nazionale di Fisica Nucleare, Catania (Italy); Ciavola, G. [Istituto Nazionale di Fisica Nucleare, Catania (Italy); Cuttone, G. [Istituto Nazionale di Fisica Nucleare, Catania (Italy); Gu, M. [Istituto Nazionale di Fisica Nucleare, Catania (Italy); Raia, G. [Istituto Nazionale di Fisica Nucleare, Catania (Italy); Rovelli, A. [Istituto Nazionale di Fisica Nucleare, Catania (Italy)

    1997-01-11

    In the framework of the EXCYT radioactive ion beam facility, now under development at LNS Catania, we have developed a new beam profile monitor based on a scintillating fibre and a photodetector. Its sensitivity allows the detection of single beam particles in pulse mode, thus representing a useful tool for diagnostics of low and very low intensity beams. (orig.).

  17. A scintillating fibre-based profiler for low intensity ion beams

    International Nuclear Information System (INIS)

    Finocchiaro, P.; Amato, A.; Ciavola, G.; Cuttone, G.; Gu, M.; Raia, G.; Rovelli, A.

    1997-01-01

    In the framework of the EXCYT radioactive ion beam facility, now under development at LNS Catania, we have developed a new beam profile monitor based on a scintillating fibre and a photodetector. Its sensitivity allows the detection of single beam particles in pulse mode, thus representing a useful tool for diagnostics of low and very low intensity beams. (orig.)

  18. Measurement of electron beams profile of pierce type electron source using sensor of used Tv tube

    International Nuclear Information System (INIS)

    Darsono; Suhartono; Suprapto; Elin Nuraini

    2015-01-01

    The measurement of an electron beam profile has been performed using electron beam monitor based on method of phosphorescent materials. The main components of the electron beam monitor consists of a fluorescent sensor using a used Tv tube, CCTV camera to record images on a Tv screen, video adapter as interface between CCTV and laptop, and the laptop as a viewer and data processing. Two Pierce-type electron sources diode and triode was measured the shape of electron beam profile in real time. Results of the experiments showed that the triode electron source of Pierce type gave the shape of electron beam profiles better than that of the diode electron source .The anode voltage is not so influential on the beam profile shape. The focused voltage in the triode electron source is so influence to the shape of the electron beam profile, but above 5 kV no great effect. It can be concluded that the electron beam monitor can provide real time observations and drawings shape of the electron beam profile displayed on the used Tv tube glass screen which is the real picture of the shape of the electron beam profile. Triode electron source produces a better electron beam profile than that of the diode electron source. (author)

  19. High-resolution spectral analysis of light from neutral beams and ion source plasmas

    International Nuclear Information System (INIS)

    McNeill, D.H.; Kim, J.

    1980-05-01

    The spectral distributions of Balmer alpha emission from 7- and 22-cm-diam neutral hydrogen beams have been measured with a Fabry-Perot interferometer to obtain information on the beam energy, divergence, and species composition. Results of these measurements are compared with other data on the beam properties to evaluate high-resolution spectroscopy as a beam diagnostic technique. Measurements on ion source plasmas and on beam-produced background plasmas yield average neutral atom energies of approximately 0.3 and 2.5 eV, respectively

  20. High resolution line for secondary radioactive beams at the U400M cyclotron

    International Nuclear Information System (INIS)

    Rodin, A.M.; Sidorchuk, S.I.; Stepantsov, S.V.

    1996-01-01

    For implementation of an experimental program for studying nuclear reactions with radioactive ion beams in the energy domain of 20 through 80 MeV · A the high resolution beam line ACCULINNA was put into commissioning on a primary beam line of the JINR U-400M cyclotron. By means of nuclear fragmentation of the 14 N beam with the energy of 51 MeV · A on the 170 mg/cm 2 carbon target radioactive beams of 6 He, 8 He and 8 B were obtained. Possibilities of further development of the set-up are discussed. 6 refs., 7 figs., 2 tabs

  1. Development of a high-resolution cavity-beam position monitor

    Science.gov (United States)

    Inoue, Yoichi; Hayano, Hitoshi; Honda, Yosuke; Takatomi, Toshikazu; Tauchi, Toshiaki; Urakawa, Junji; Komamiya, Sachio; Nakamura, Tomoya; Sanuki, Tomoyuki; Kim, Eun-San; Shin, Seung-Hwan; Vogel, Vladimir

    2008-06-01

    We have developed a high-resolution cavity-beam position monitor (BPM) to be used at the focal point of the ATF2, which is a test beam line that is now being built to demonstrate stable orbit control at ˜nanometer resolution. The design of the cavity structure was optimized for the Accelerator Test Facility (ATF) beam in various ways. For example, the cavity has a rectangular shape in order to isolate two dipole modes in orthogonal directions, and a relatively thin gap that is less sensitive to trajectory inclination. A two stage homodyne mixer with highly sensitive electronics and phase-sensitive detection was also developed. Two BPM blocks, each containing two cavity BPMs, were installed in the existing ATF beam line using a rigid support frame. After testing the basic characteristics, we measured the resolution using three BPMs. The system demonstrated 8.7 nm position resolution over a dynamic range of 5μm.

  2. Sub-nanometer resolution XPS depth profiling: Sensing of atoms

    Energy Technology Data Exchange (ETDEWEB)

    Szklarczyk, Marek, E-mail: szklarcz@chem.uw.edu.pl [Faculty of Chemistry, University of Warsaw, ul. Pasteura 1, 02-093 Warsaw (Poland); Shim-Pol, ul. Lubomirskiego 5, 05-080 Izabelin (Poland); Macak, Karol; Roberts, Adam J. [Kratos Analytical Ltd, Wharfside, Trafford Wharf Road, Manchester, M17 1GP (United Kingdom); Takahashi, Kazuhiro [Kratos XPS Section, Shimadzu Corp., 380-1 Horiyamashita, Hadano, Kanagawa 259-1304 (Japan); Hutton, Simon [Kratos Analytical Ltd, Wharfside, Trafford Wharf Road, Manchester, M17 1GP (United Kingdom); Głaszczka, Rafał [Shim-Pol, ul. Lubomirskiego 5, 05-080 Izabelin (Poland); Blomfield, Christopher [Kratos Analytical Ltd, Wharfside, Trafford Wharf Road, Manchester, M17 1GP (United Kingdom)

    2017-07-31

    Highlights: • Angle resolved photoelectron depth profiling of nano thin films. • Sensing atomic position in SAM films. • Detection of direction position of adsorbed molecules. - Abstract: The development of a method capable of distinguishing a single atom in a single molecule is important in many fields. The results reported herein demonstrate sub-nanometer resolution for angularly resolved X-ray photoelectron spectroscopy (ARXPS). This is made possible by the incorporation of a Maximum Entropy Method (MEM) model, which utilize density corrected electronic emission factors to the X-ray photoelectron spectroscopy (XPS) experimental results. In this paper we report on the comparison between experimental ARXPS results and reconstructed for both inorganic and organic thin film samples. Unexpected deviations between experimental data and calculated points are explained by the inaccuracy of the constants and standards used for the calculation, e.g. emission factors, scattering intensity and atomic density through the studied thickness. The positions of iron, nitrogen and fluorine atoms were determined in the molecules of the studied self-assembled monolayers. It has been shown that reconstruction of real spectroscopic data with 0.2 nm resolution is possible.

  3. Computed tomographic reconstruction of beam profiles with a multi-wire chamber

    International Nuclear Information System (INIS)

    Alonso, J.R.; Tobias, C.A.; Chu, W.T.

    1979-03-01

    MEDUSA (MEdical Dose Uniformity SAmpler), a 16 plane multi-wire proportional chamber, has been built to accurately measure beam profiles. The large number of planes allows for reconstruction of highly detailed beam intensity structures by means of Fourier convolution reconstruction techniques. This instrument is being used for verification and tuning of the Bevalac radiotherapy beams, but has potential applications in many beam profile monitoring situations

  4. Elemental thin film depth profiles by ion beam analysis using simulated annealing - a new tool

    International Nuclear Information System (INIS)

    Jeynes, C; Barradas, N P; Marriott, P K; Boudreault, G; Jenkin, M; Wendler, E; Webb, R P

    2003-01-01

    Rutherford backscattering spectrometry (RBS) and related techniques have long been used to determine the elemental depth profiles in films a few nanometres to a few microns thick. However, although obtaining spectra is very easy, solving the inverse problem of extracting the depth profiles from the spectra is not possible analytically except for special cases. It is because these special cases include important classes of samples, and because skilled analysts are adept at extracting useful qualitative information from the data, that ion beam analysis is still an important technique. We have recently solved this inverse problem using the simulated annealing algorithm. We have implemented the solution in the 'IBA DataFurnace' code, which has been developed into a very versatile and general new software tool that analysts can now use to rapidly extract quantitative accurate depth profiles from real samples on an industrial scale. We review the features, applicability and validation of this new code together with other approaches to handling IBA (ion beam analysis) data, with particular attention being given to determining both the absolute accuracy of the depth profiles and statistically accurate error estimates. We include examples of analyses using RBS, non-Rutherford elastic scattering, elastic recoil detection and non-resonant nuclear reactions. High depth resolution and the use of multiple techniques simultaneously are both discussed. There is usually systematic ambiguity in IBA data and Butler's example of ambiguity (1990 Nucl. Instrum. Methods B 45 160-5) is reanalysed. Analyses are shown: of evaporated, sputtered, oxidized, ion implanted, ion beam mixed and annealed materials; of semiconductors, optical and magnetic multilayers, superconductors, tribological films and metals; and of oxides on Si, mixed metal silicides, boron nitride, GaN, SiC, mixed metal oxides, YBCO and polymers. (topical review)

  5. The low energy muon beam profile monitor for the muon g-2/EDM experiment at J-PARC

    Science.gov (United States)

    Razuvaev, G. P.; Bae, S.; Choi, H.; Choi, S.; Ko, H. S.; Kim, B.; Kitamura, R.; Mibe, T.; Otani, M.

    2017-09-01

    The muon g-2/EDM experiment at J-PARC aims to measure the muon anomalous magnetic moment and electric dipole moment with high precision by utilising an ultracold muon beam. The current muon g-2 discrepancy between the Standard Model prediction and the experimental value is about 3.5 standard deviations. This experiment requires a development of the muon LINAC to accelerate thermal muons to the 300 MeV/c momentum. Detectors for beam diagnostics play a key role in such an experiment. The beam profile monitoring system has been designed to measure the profile of the low energy muon beam. It was tested during two beam tests in 2016 at the MLF D2 line at J-PARC. The detector was used with positive muons, Mu-(μ+ e- e-), p and H-, e- and UV light. The system overview and preliminary results are given. Special attention is paid to the spatial resolution of the beam profile monitor and online monitor software used during data taking.

  6. Overview of laserwire beam profile and emittance measurements for high power proton accelerators

    CERN Document Server

    Gibson, S M; Bosco, A; Gabor, C; Pozimski, J; Savage, P; Hofmann, T

    2013-01-01

    Laserwires were originally developed to measure micron-sized electron beams via Compton scattering, where traditional wire scanners are at the limit of their resolution. Laserwires have since been applied to larger beamsize, high power H$^-$ ion beams, where the non-invasive method can probe beam densities that would damage traditional diagnostics. While photo-detachment of H$^-$ ions is now routine to measure beam profiles, extending the technique to transverse and longitudinal emittance measurements is a key aim of the laserwire emittance scanner under construction at the Front End Test Stand (FETS) at the RAL. A pulsed, 30 kHz, 8kW peak power laser is fibrecoupled to motorized collimating optics, which controls the position and thickness of the laserwire delivered to the H- interaction chamber. The laserwire slices out a beamlet of neutralized particles, which propagate to a downstream scintillator and camera. The emittance is reconstructed from 2D images as the laserwire position is scanned. Results from ...

  7. Influence of rebinning on the reconstructed resolution of fan-beam SPECT

    International Nuclear Information System (INIS)

    Koole, M.; D'Asseler, Y.; Staelens, S.; Vandenberghe, S.; Eede, I. van den; Walle, R. van de; Lemahieu, I.

    2002-01-01

    Aim: Fan-beam projection data can be rebinned to a parallel-beam geometry. This rebinning operation allows these data to be reconstructed with algorithms for parallel-beam projection data. The advantage of such an operation is that a dedicated projection/backprojection step for fan-beam geometry doesn't need to be developed. In clinical practice bilinear interpolation is often used for this rebinning operation. The aim of this study is to investigate the influence of the rebinning operation on the resolution properties of the reconstructed SPECT-image. Materials and methods: We have simulated the resolution properties of a fan-beam collimator, used in clinical routine, by means of a dedicated projector operation which models the distance dependent sensitivity and resolution of the collimator. With this projector, we generated noise-free sinograms for a point source located at various distances from the center of rotation. The number of angles of these sinograms varied from 60 to 180, corresponding to a step angle of 6 to 2 degrees. These generated fan-beam projection data were reconstructed directly with a filtered backprojection algorithm for fan-beam projection data, which consists of weighting and filtering the projection data with a ramp filter and of a weighted backprojection. Next, the generated fan-beam projection data were rebinned by means of bilinear interpolation and reconstructed with standard filtered backprojection for parallel-beam data. A two-dimensional Gaussian was fitted to the two point sources, one reconstructed with FBP for fan-beam and one reconstructed with FBP for parallel-beam after rebinning, yielding an estimate for the reconstructed Full Width at Half Maximum (FWHM) in the radial and tangential direction, for different locations in the field of view. Results: Results show little difference in resolution degradation in the radial direction between direct reconstruction and reconstruction after rebinning. However, significant loss in

  8. Experimental three-dimensional beam profiling and modeling of a terahertz beam generated from a two-color air plasma

    DEFF Research Database (Denmark)

    Pedersen, Pernille Klarskov; Strikwerda, Andrew; Iwaszczuk, Krzysztof

    2013-01-01

    a sharp, conical intensity profile resembling a donut, and in the focal region the beam collapses to a central, Lorentz-shaped profile. The Lorentzian intensity profile in the focal region can be explained by considering the frequency-dependent spot size derived from measurements of the Gouy phase shift...... in the focal region, and the transition from the donut profile to a central peak is consistent with propagation of a Bessel–Gauss beam, as shown by simulations based on a recent transient photocurrent model (You et al 2012 Phys. Rev. Lett. 109 183902). We combine our measurements to the first full 3D...

  9. On the use of magnetic buckets for ion beam profile tailoring

    International Nuclear Information System (INIS)

    MacGill, R. A.; Vizir, A.; Brown, I. G.

    2000-01-01

    Magnetic multipole plasma confinement geometries employing permanent magnet ''buckets'' are used extensively for a range of laboratory plasma applications. Among the several consequences for plasma confinement is the important result that the plasma can acquire a more-or-less flat density profile, which when embodied in an ion source, can also lead to a flat profile for the extracted ion beam. For many applications a uniform ion beam current density profile is quite advantageous, for example, for carrying out large-area ion implantation. There are, however, inherent limitations on the extent to which this approach to beam ''homogenization'' can be utilized, and even for a perfectly flat profile in the immediate postextraction region, the beam will evolve toward Gaussian as it propagates downstream. Here we describe the rare-earth permanent magnet bucket that we have incorporated into our broad-beam vacuum arc ion source, and its effect on the beam profile at the extractor and downstream. The experimental results are compared with a simple model for the beam profile evolution with axial distance. We find that the beam loses memory of its initially flat profile and relaxes to a more-or-less Gaussian shape in a relatively short axial distance ∼w/4θ, where w is the initial width of the flat beam profile and θ is the beamlet divergence half angle. (c) 2000 American Institute of Physics

  10. Design and performance of a high resolution, low latency stripline beam position monitor system

    Science.gov (United States)

    Apsimon, R. J.; Bett, D. R.; Blaskovic Kraljevic, N.; Burrows, P. N.; Christian, G. B.; Clarke, C. I.; Constance, B. D.; Dabiri Khah, H.; Davis, M. R.; Perry, C.; Resta López, J.; Swinson, C. J.

    2015-03-01

    A high-resolution, low-latency beam position monitor (BPM) system has been developed for use in particle accelerators and beam lines that operate with trains of particle bunches with bunch separations as low as several tens of nanoseconds, such as future linear electron-positron colliders and free-electron lasers. The system was tested with electron beams in the extraction line of the Accelerator Test Facility at the High Energy Accelerator Research Organization (KEK) in Japan. It consists of three stripline BPMs instrumented with analogue signal-processing electronics and a custom digitizer for logging the data. The design of the analogue processor units is presented in detail, along with measurements of the system performance. The processor latency is 15.6 ±0.1 ns . A single-pass beam position resolution of 291 ±10 nm has been achieved, using a beam with a bunch charge of approximately 1 nC.

  11. Sub 100 nm proton beam micromachining: theoretical calculations on resolution limits

    International Nuclear Information System (INIS)

    Kan, J.A. van; Sum, T.C.; Osipowicz, T.; Watt, F.

    2000-01-01

    Proton beam micromachining is a novel direct-write process for the production of three-dimensional (3D) microstructures. A focused beam of MeV protons is scanned in a pre-determined pattern over a suitable resist material (e.g. PMMA or SU-8) and the latent image formed is subsequently developed chemically. In this paper calculations on theoretical resolution limits of proton beam micromachined three-dimensional microstructures are presented. Neglecting the finite beam size, a Monte Carlo ion transport code was used in combination with a theoretical model describing the delta-ray (δ-ray) energy deposition to determine the lateral energy deposition distribution in PMMA resist material. The energy deposition distribution of ion induced secondary electrons (δ-rays) has been parameterized using analytical models. It is assumed that the attainable resolution is limited by a convolution of the spread of the ion beam and energy deposition of the δ-rays

  12. Spectrally resolved measurements of the terahertz beam profile generated from a two-color air plasma

    DEFF Research Database (Denmark)

    Pedersen, Pernille Klarskov; Zalkovskij, Maksim; Strikwerda, Andrew

    2014-01-01

    Using a THz camera and THz bandpass filters, we measure the frequency - resolved beam profile emitted from a two - color air plasma. We observe a frequency - independent emission angle from the plasma .......Using a THz camera and THz bandpass filters, we measure the frequency - resolved beam profile emitted from a two - color air plasma. We observe a frequency - independent emission angle from the plasma ....

  13. Resolution and drift measurements on the Advanced Photon Source beam position monitors

    International Nuclear Information System (INIS)

    Chung, Y.; Kahana, E.

    1994-01-01

    The resolution and long-term drift of the Advanced Photon Source (APS) beam position monitor (BPM) electronics were measured using the charged particle beams in the ESRF storage ring with various beam current and configurations (single bunch, 8 and 16 equally spaced bunches, and 1/3-fill). The energy of the stored electrons was 6 GeV. The integrated BPM electronics system as used for this work is capable of measuring the beam position on a turn-by-turn basis, which can be accumulated for N turns (N = 2 n , n = 1, 2, ... , 11). Estimation of the BPM resolution apart from the low-frequency beam motion was made by measuring the standard deviation in the measured beam position with different Ns. The analysis of the results indicates a BPM resolution of 18/√ N [μm] for the APS storage ring, which is equivalent to 0.07 μm/√Hz. For the miniature insertion device BPM with 2.8 times higher sensitivity, the resolution will be 0.02 μm/√Hz. The long-term drift of the BPM electronics independent of the actual beam motion was measured at 2 μm/hr, which settled after approximately 1.5 hours. This drift can be attributed mainly to the temperature effect. Comparison of the results with the laboratory measurements shows good agreement. Implication of the BPM resolution limit on the proposed global and local beam position feedback systems for the APS storage ring will also be discussed

  14. Resolution and drift measurements on the advanced photon source beam position monitor

    International Nuclear Information System (INIS)

    Chung, Y.; Kahana, E.

    1995-01-01

    The resolution and long-term drift of the Advanced Photon Source (APS) beam position monitor (BPM) electronics were measured using the charged particle beams in the ESRF storage ring with various beam current and configurations (single bunch, 8 and 16 equally spaced bunches, and 1/3-fill). The energy of the stored electrons was 6 GeV. The integrated BPM electronics system as used for this work is capable of measuring the beam position on a turn-by-turn basis, which can be accumulated for N turns (N=2 n , n=1,2,...,11) . Estimation of the BPM resolution apart from the low-frequency beam motion was made by measuring the standard deviation in the measured beam position with different Ns. The analysis of the results indicates a BPM resolution of 18/√N [μm] for the APS storage ring, which is equivalent to 0.07 μm/√Hz. For the miniature insertion device BPM with 2.8 times higher sensitivity, the resolution will be 0.02 μm/√Hz. The long-term drift of the BPM electronics independent of the actual beam motion was measured at 2 μm/hr, which settled after approximately 1.5 hours. This drift can be attributed mainly to the temperature effect. Comparison of the results with the laboratory measurements shows good agreement. Implication of the BPM resolution limit on the proposed global and local beam position feedback systems for the APS storage ring will also be discussed. copyright 1995 American Institute of Physics

  15. 2-D Low Energy Electron Beam Profile Measurement Based on Computer Tomography Algorithm with Multi-Wire Scanner

    CERN Document Server

    Yu, Nengjie; Li Qing Feng; Tang, Chuan-Xiang; Zheng, Shuxin

    2005-01-01

    A new method for low energy electron beam profile measurement is advanced, which presents a full 2-D beam profile distribution other than the traditional 2-D beam profile distribution given by 1-D vertical and horizontal beam profiles. The method is based on the CT (Computer Tomography) algorithm. Multi-sets of data about the 1-D beam profile projections are attained by rotating the multi-wire scanner. Then a 2-D beam profile is reconstructed from these projections with CT algorithm. The principle of this method is presented. The simulation and the experiment results are compared and analyzed in detail.

  16. Limits to the resolution of beam size measurement from fluorescent screens due to the thickness of the phosphor

    International Nuclear Information System (INIS)

    Johnson, C.D.

    1988-01-01

    This paper discusses the use of fluorescent screens for the measurement of beam profiles on non-circulating particle beams. An expression for the intensity of the beam profile as a function of phosphor thickness is given. 3 refs., 8 figs

  17. SU-F-I-76: Fluoroscopic X-Ray Beam Profiles for Spectra Incorporating Copper Filtration

    Energy Technology Data Exchange (ETDEWEB)

    Wunderle, K [Cleveland Clinic Foundation, Cleveland, OH (United States); Wayne State University School of Medicine, Detroit, MI (United States); Godley, A; Shen, Z; Dong, F [Cleveland Clinic Foundation, Cleveland, OH (United States); Rakowski, J [Wayne State University School of Medicine, Detroit, MI (United States)

    2016-06-15

    Purpose: The purpose of this investigation is to characterize and quantify X-ray beam profiles for fluoroscopic x-ray beam spectra incorporating spectral (copper) filtration. Methods: A PTW (Freiburg, Germany) type 60016 silicon diode detector and PTW MP3 water tank were used to measure X-ray beam profiles for 60, 80, 100 and 120 kVp x-ray beams at five different copper filtration thicknesses ranging from 0–0.9 mm at 22 and 42 cm fields of view and depths of 1, 5, and 10 cm in both the anode-cathode axis (inplane) and cross-plane directions. All measurements were acquired on a Siemens (Erlangen, Germany) Artis ZeeGo fluoroscope inverted from the typical orientation providing an x-ray beam originating from above the water surface with the water level set at 60 cm from the focal spot. Results: X-ray beam profiles for beam spectra without copper filtration compared well to previously published data by Fetterly et al. [Med Phys, 28, 205 (2001)]. Our data collection benefited from the geometric orientation of the fluoroscope, providing a beam perpendicular to the tank water surface, rather than through a thin side wall as did the previously mentioned study. Profiles for beams with copper filtration were obtained which have not been previously investigated and published. Beam profiles in the anode-cathode axis near the surface and at lower x-ray energy exhibited substantial heel effect, which became less pronounced at greater depth. At higher energy with copper filtration in the beam, the dose falloff out-of-field became less pronounced, as would be anticipated given higher scatter photon energy. Conclusion: The x-ray beam profile data for the fluoroscopic x-ray beams incorporating copper filtration are intended for use as reference data for estimating doses to organs or soft tissue, including fetal dose, involving similar beam qualities or for comparison with mathematical models.

  18. Study on energy and position resolution of MWPC for the Beijing e/π test beam

    International Nuclear Information System (INIS)

    Shen Ji; Chen Ziyu; Ye Yunxiu; Cui Xiangzong; Li Jiacai

    2006-01-01

    This paper describes the research on the energy and position resolution of the MWPC used in the e/π Test Beam on BEPC (Beijing Electron Positron Collider), which localizes the particles of e/π by the readout method of gravity center of the induced charges on the cathode strips. The spatial resolution of about 0.24 mm and energy resolution of 17% for 5.9 keV γ photons are attained at the 3700 V anode voltage. For the 1.1 GeV electrons, the spatial resolution of 0.3 mm is obtained. The contributions of various factors to energy resolution are analysed. It is found that energy resolution is changed with the anode voltage and there exists a least energy resolution. The reasons for these are discussed. (authors)

  19. A metrology system for a high resolution cavity beam position monitor system

    Energy Technology Data Exchange (ETDEWEB)

    Walston, Sean, E-mail: walston2@llnl.gov [Lawrence Livermore National Laboratory, 7000 East Ave., L-181, Livermore, CA 94550 (United States); Boogert, Stewart [Royal Holloway, University of London, Egham (United Kingdom); Chung, Carl; Fitsos, Pete [Lawrence Livermore National Laboratory, 7000 East Ave., L-181, Livermore, CA 94550 (United States); Frisch, Joe [Stanford Linear Accelerator Center, Menlo Park, CA (United States); Gronberg, Jeff [Lawrence Livermore National Laboratory, 7000 East Ave., L-181, Livermore, CA 94550 (United States); Hayano, Hitoshi [High Energy Accelerator Research Organization (KEK), Tsukuba-shi, Ibaraki-ken (Japan); Hinton, Shantell [Stanford Linear Accelerator Center, Menlo Park, CA (United States); Honda, Yosuke [High Energy Accelerator Research Organization (KEK), Tsukuba-shi, Ibaraki-ken (Japan); Khainovski, Oleg; Kolomensky, Yury; Loscutoff, Peter [University of California and Lawrence Berkeley National Laboratory, Berkeley, CA (United States); Lyapin, Alexey; Malton, Stephen [University College London, London (United Kingdom); May, Justin; McCormick, Douglas [Stanford Linear Accelerator Center, Menlo Park, CA (United States); Meller, Robert [Cornell University, Ithaca, NY (United States); Miller, David [University College London, London (United Kingdom); Orimoto, Toyoko [University of California and Lawrence Berkeley National Laboratory, Berkeley, CA (United States); California Institute of Technology, Pasadena, CA (United States); Ross, Marc [Stanford Linear Accelerator Center, Menlo Park, CA (United States); Fermi National Accelerator Laboratory, Batavia, IL (United States); and others

    2013-11-11

    International Linear Collider (ILC) interaction region beam sizes and component position stability requirements will likely be as small as a few nanometers. It is important to the ILC design effort to demonstrate that these tolerances can be achieved–ideally using a beam-based stability measurement. We developed a high resolution RF cavity Beam Position Monitor (BPM) system. A triplet of these BPMs, installed in the extraction line of the KEK Accelerator Test Facility (ATF) and tested with its ultra-low emittance beam, achieved a position measurement resolution of 15 nm. A metrology system for the three BPMs was subsequently installed. This system employed optical encoders to measure each BPM's position and orientation relative to a zero-coefficient of thermal expansion carbon fiber frame. We have demonstrated that the three BPMs behave as a rigid-body at the level of less than 5 nm.

  20. Technologies and R&D for a High Resolution Cavity BPM for the CLIC Main Beam

    CERN Document Server

    Towler, J R; Soby, L; Wendt, M; Boogert, S T; Cullinan, F J; Lyapin, A

    2013-01-01

    The Main Beam (MB) linac of the Compact Linear Collider (CLIC) requires a beam orbit measurement system with high spatial (50 nm) and high temporal resolution (50 ns) to resolve the beam position within the 156 ns long bunch train, traveling on an energy-chirped, minimum dispersive trajectory. A 15 GHz prototype cavity BPM has been commissioned in the probe beam-line of the CTF3 CLIC Test Facility. We discuss performance and technical details of this prototype installation, including the 15 GHz analogue downconverter, the data acquisition and the control electronics and software. An R&D outlook is given for the next steps, which requires a system of 3 cavity BPMs to investigate the full resolution potential.

  1. A metrology system for a high resolution cavity beam position monitor system

    Science.gov (United States)

    Walston, Sean; Boogert, Stewart; Chung, Carl; Fitsos, Pete; Frisch, Joe; Gronberg, Jeff; Hayano, Hitoshi; Hinton, Shantell; Honda, Yosuke; Khainovski, Oleg; Kolomensky, Yury; Loscutoff, Peter; Lyapin, Alexey; Malton, Stephen; May, Justin; McCormick, Douglas; Meller, Robert; Miller, David; Orimoto, Toyoko; Ross, Marc; Slater, Mark; Smith, Steve; Smith, Tonee; Terunuma, Nobuhiro; Thomson, Mark; Urakawa, Junji; Vogel, Vladimir; Ward, David; White, Glen

    2013-11-01

    International Linear Collider (ILC) interaction region beam sizes and component position stability requirements will likely be as small as a few nanometers. It is important to the ILC design effort to demonstrate that these tolerances can be achieved-ideally using a beam-based stability measurement. We developed a high resolution RF cavity Beam Position Monitor (BPM) system. A triplet of these BPMs, installed in the extraction line of the KEK Accelerator Test Facility (ATF) and tested with its ultra-low emittance beam, achieved a position measurement resolution of 15 nm. A metrology system for the three BPMs was subsequently installed. This system employed optical encoders to measure each BPM's position and orientation relative to a zero-coefficient of thermal expansion carbon fiber frame. We have demonstrated that the three BPMs behave as a rigid-body at the level of less than 5 nm.

  2. Spatial resolution in optical transition radiation (OTR) beam diagnostics

    International Nuclear Information System (INIS)

    Castellano, M.; Verzilov, V. A.

    1998-06-01

    An evaluation of the OTR single particle image dimension is obtained using diffraction theory based on a realistic description of the radiation source. This approach allows the analysis of the effect of the finite size of the emitting screen and of the imaging system. The role of practical experimental conditions in treating the intensity tail problem is estimated. It is shown that by exploiting the polarization properties of OTR, a considerable enhancement in the spatial resolution can be achieved, which becomes very similar to that of a standard point source

  3. Exploring the Spatial Resolution of the Photothermal Beam Deflection Technique in the Infrared Region

    CERN Document Server

    Seidel, Wolfgang

    2004-01-01

    In photothermal beam deflection spectroscopy (PTBD) generating and detection of thermal waves occur generally in the sub-millimeter length scale. Therefore, PTBD provides spatial information about the surface of the sample and permits imaging and/or microspectrometry. Recent results of PTBD experiments are presented with a high spatial resolution which is near the diffraction limit of the infrared pump beam (CLIO-FEL). We investigated germanium substrates showing restricted O+-doped regions with an infrared absorption line at a wavelength around 11.6 microns. The spatial resolution was obtained by strongly focusing the probe beam (i.e. a HeNe laser) on a sufficiently small spot. The strong divergence makes it necessary to refocus the probe beam in front of the position detector. The influence of the focusing elements on spatial resolution and signal-to-noise ratio is discussed. In future studies we expect an enhanced spatial resolution due to an extreme focusing of the probe beam leading to a highly sensitive...

  4. High temperature and high resolution uv photoelectron spectroscopy using supersonic molecular beams

    International Nuclear Information System (INIS)

    Wang, Lai-Sheng; Reutt-Robey, J.E.; Niu, B.; Lee, Y.T.; Shirley, D.A.

    1989-07-01

    A high temperature molecular beam source with electron bombardment heating has been built for high resolution photoelectron spectroscopic studies of high temperature species and clusters. This source has the advantages of: producing an intense, continuous, seeded molecular beam, eliminating the interference of the heating mechanism from the photoelectron measurement. Coupling the source with our hemispherical electron energy analyzer, we can obtain very high resolution HeIα (584 angstrom) photoelectron spectra of high temperature species. Vibrationally-resolved photoelectron spectra of PbSe, As 2 , As 4 , and ZnCl 2 are shown to demonstrate the performance of the new source. 25 refs., 8 figs., 1 tab

  5. Fen+ beam profile diagnostics based on Al2O3: Cr scintillating screen

    International Nuclear Information System (INIS)

    He Tie; Lei Jiarong; Liu Meng; An Li; Wang Xinhua; Zheng Pu

    2013-01-01

    Some techniques of beam profile measurements such as wire rotating scan, Faraday cups array and infrared imaging were investigated. A measurement device was built based on scintillating screen to cater for the demand of accelerator beam profile diagnostics. The device was bombarded under several tens to hundred nanoampere Fe n+ (n=5-12) ion beam. The Fe n+ ion beam experiment shows that the imaging saturation is mainly caused by light intensity rather than scintillating screen. A way to solve the saturation problem with a specially developed lens was mentioned. The grayscale of beam profile imaging is approximately linear with respect to the beam intensity, and the reason for formation of this relationship was analyzed. (authors)

  6. Random source generating far field with elliptical flat-topped beam profile

    International Nuclear Information System (INIS)

    Zhang, Yongtao; Cai, Yangjian

    2014-01-01

    Circular and rectangular multi-Gaussian Schell-model (MGSM) sources which generate far fields with circular and rectangular flat-topped beam profiles were introduced just recently (Sahin and Korotkova 2012 Opt. Lett. 37 2970; Korotkova 2014 Opt. Lett. 39 64). In this paper, a random source named an elliptical MGSM source is introduced. An analytical expression for the propagation factor of an elliptical MGSM beam is derived. Furthermore, an analytical propagation formula for an elliptical MGSM beam passing through a stigmatic ABCD optical system is derived, and its propagation properties in free space are studied. It is interesting to find that an elliptical MGSM source generates a far field with an elliptical flat-topped beam profile, being qualitatively different from that of circular and rectangular MGSM sources. The ellipticity and the flatness of the elliptical flat-topped beam profile in the far field are determined by the initial coherence widths and the beam index, respectively. (paper)

  7. Parameters affecting profile shape of a high energy low current thin ion beam. Vol. 2

    Energy Technology Data Exchange (ETDEWEB)

    Abdel Salam, F W; Moustafa, O A; El-Khabeary, H [Accelerators Department, Nuclear Research Center, Atomic Energy Authority, Cairo, (Egypt)

    1996-03-01

    The shape of the profile of a high energy, low current beam of finite length has beam investigated. The beam profile shape depends on the initial beam radius, beam perveance, atomic mass number, charge state of ions, and beam length. These parameters can affect the relation between the initial beam radius and the corresponding final one. An optimum initial beam radius corresponding to minimum final beam at the target has been formulated and the relation between them is deduced taking account of the space charge effect. The minimum beam radius at the target was found to be equal to 2.3 of the optimum initial radius. It is concluded that in order to obtain a small beam radius at a target placed at a finite distance from an ion source, a beam of a low perveance, low atomic mass number and high number of electronic charge is required. This is an important detection for micro machining applications using the oscillating electron ion source which produces nearly paraxial thin beam of low perveance. 12 figs.

  8. A high resolution atlas of Mg II profiles

    Science.gov (United States)

    Ewald, R.; Nichols-Bohlin, Joy Y.; Kondo, Yoji

    1990-01-01

    An atlas of high dispersion Mg II profiles for standard stars of spectral types B0 through G9 is presented. The atlas contains plots of the Mg II profiles for approximately 65 stars and associated equivalent width measurements for both absorption and emission components, and the subordinate lines. The atlas is used to investigate systematic behavior of the Mg II profiles and correlation of the behavior with spectral classification.

  9. Method of measuring a profile of the density of charged particles in a particle beam

    International Nuclear Information System (INIS)

    Hyman, L.G.; Jankowski, D.J.

    1975-01-01

    A profile of the relative density of charged particles in a beam is obtained by disposing a number of rods parallel to each other in a plane perpendicular to the beam and shadowing the beam. A second number of rods is disposed perpendicular to the first rods in a plane perpendicular to the beam and also shadowing the beam. Irradiation of the rods by the beam of charged particles creates radioactive isotopes in a quantity proportional to the number of charged particles incident upon the rods. Measurement of the radioactivity of each of the rods provides a measure of the quantity of radioactive material generated thereby and, together with the location of the rods, provides information sufficient to identify a profile of the density of charged particles in the beam

  10. A laser-based beam profile monitor for the SLC/SLD interaction region

    International Nuclear Information System (INIS)

    Alley, R.; Arnett, D.; Bong, E.; Colocho, W.; Frisch, J.; Horton-Smith, S.; Inman, W.; Jobe, K.; Kotseroglou, T.; McCormick, D.; Nelson, J.; Scheeff, M.; Wagner, S.; Ross, M.C.

    1996-01-01

    Beam size estimates made using beam-beam deflections are used for optimization of the Stanford linear collider (SLC) electron-positron beam sizes. Typical beam sizes and intensities expected for 1996 operations are 2.1 x 0.6 μm (x, y) at 4.0.10 10 particles per pulse. Conventional profile monitors, such as scanning wires, fail at charge densities well below this. The laser-based profile monitor uses a finely-focused 350-nm wavelength tripled YLF laser pulse that traverses the particle beam path about 29 cm away from the e + /e - IP. Compton scattered photons and degraded e + /e - are detected as the beam is steered across the laser pulse. The laser pulse has a transverse size of 380 nm and a Rayleigh range of about 5 μm. (orig.)

  11. Transverse beam profile measurements with slit scanner and Faraday cup at REX-ISOLDE

    CERN Document Server

    Cantero, E D; Lanaia, D; Sosa, A; Voulot, D

    2014-01-01

    The transverse profiles for the HIE-ISOLDE beams will be measured using a system composed of a scanning slit and a Faraday cup. A validation test of the proposed device was performed using the REX-ISOLDE stable beam and a prototype diagnostic box designed for HIE-ISOLDE. The slit used for this test was very thin (0.2 mm width), but still fairly good profiles could be obtained for beams with total current of around 20 pA (typical beam intensity during normal set-up procedures for REX-ISOLDE).

  12. Effects of ray profile modeling on resolution recovery in clinical CT

    International Nuclear Information System (INIS)

    Hofmann, Christian; Knaup, Michael; Kachelrieß, Marc

    2014-01-01

    Purpose: Iterative image reconstruction gains more and more interest in clinical routine, as it promises to reduce image noise (and thereby patient dose), to reduce artifacts, or to improve spatial resolution. However, among vendors and researchers, there is no consensus of how to best achieve these goals. The authors are focusing on the aspect of geometric ray profile modeling, which is realized by some algorithms, while others model the ray as a straight line. The authors incorporate ray-modeling (RM) in nonregularized iterative reconstruction. That means, instead of using one simple single needle beam to represent the x-ray, the authors evaluate the double integral of attenuation path length over the finite source distribution and the finite detector element size in the numerical forward projection. Our investigations aim at analyzing the resolution recovery (RR) effects of RM. Resolution recovery means that frequencies can be recovered beyond the resolution limit of the imaging system. In order to evaluate, whether clinical CT images can benefit from modeling the geometrical properties of each x-ray, the authors performed a 2D simulation study of a clinical CT fan-beam geometry that includes the precise modeling of these geometrical properties. Methods: All simulations and reconstructions are performed in native fan-beam geometry. A water phantom with resolution bar patterns and a Forbild thorax phantom with circular resolution patterns representing calcifications in the heart region are simulated. An FBP reconstruction with a Ram–Lak kernel is used as a reference reconstruction. The FBP is compared to iterative reconstruction techniques with and without RM: An ordered subsets convex (OSC) algorithm without any RM (OSC), an OSC where the forward projection is modeled concerning the finite focal spot and detector size (OSC-RM) and an OSC with RM and with a matched forward and backprojection pair (OSC-T-RM, T for transpose). In all cases, noise was matched to

  13. Untangling the contributions of image charge and laser profile for optimal photoemission of high-brightness electron beams

    International Nuclear Information System (INIS)

    Portman, J.; Zhang, H.; Makino, K.; Ruan, C. Y.; Berz, M.; Duxbury, P. M.

    2014-01-01

    Using our model for the simulation of photoemission of high brightness electron beams, we investigate the virtual cathode physics and the limits to spatio-temporal and spectroscopic resolution originating from the image charge on the surface and from the profile of the exciting laser pulse. By contrasting the effect of varying surface properties (leading to expanding or pinned image charge), laser profiles (Gaussian, uniform, and elliptical), and aspect ratios (pancake- and cigar-like) under different extraction field strengths and numbers of generated electrons, we quantify the effect of these experimental parameters on macroscopic pulse properties such as emittance, brightness (4D and 6D), coherence length, and energy spread. Based on our results, we outline optimal conditions of pulse generation for ultrafast electron microscope systems that take into account constraints on the number of generated electrons and on the required time resolution.

  14. Development of a high-resolution cavity-beam position monitor

    Directory of Open Access Journals (Sweden)

    Yoichi Inoue

    2008-06-01

    Full Text Available We have developed a high-resolution cavity-beam position monitor (BPM to be used at the focal point of the ATF2, which is a test beam line that is now being built to demonstrate stable orbit control at ∼nanometer resolution. The design of the cavity structure was optimized for the Accelerator Test Facility (ATF beam in various ways. For example, the cavity has a rectangular shape in order to isolate two dipole modes in orthogonal directions, and a relatively thin gap that is less sensitive to trajectory inclination. A two stage homodyne mixer with highly sensitive electronics and phase-sensitive detection was also developed. Two BPM blocks, each containing two cavity BPMs, were installed in the existing ATF beam line using a rigid support frame. After testing the basic characteristics, we measured the resolution using three BPMs. The system demonstrated 8.7 nm position resolution over a dynamic range of 5  μm.

  15. Electron beam fabrication and characterization of high- resolution magnetic force microscopy tips

    NARCIS (Netherlands)

    Ruhrig, M.; Rührig, M.; Porthun, S.; Porthun, S.; Lodder, J.C.; Mc vitie, S.; Heyderman, L.J.; Johnston, A.B.; Chapman, J.N.

    1996-01-01

    The stray field, magnetic microstructure, and switching behavior of high‐resolution electron beam fabricated thin film tips for magnetic force microscopy (MFM) are investigated with different imaging modes in a transmission electron microscope (TEM). As the tiny smooth carbon needles covered with a

  16. High-resolution electron collision spectroscopy with multicharged ions in merged beams

    Energy Technology Data Exchange (ETDEWEB)

    Lestinsky, M.

    2007-04-18

    The Heidelberg ion storage ring Tsr is currently the only ring equipped with two independent devices for the collinear merging of a cold electron beam with stored ions. This greatly improves the potential of electron-ion collision experiments, as the ion beam can be cooled with one electron beam, while the other one is used as a dedicated target for energy-resolved electron collision processes, such as recombination. The work describes the implementation of this system for rst electron collision spectroscopy experiments. A detection system has been realized including an ion detector and specroscopic beam-control software and instrumentation. Moreover, in order to improve the spectroscopic resolution systematical studies of intrinsic relaxation processes in the electron beam have been carried out. These include the dependence on the electron beam density, the magnetic guiding eld strength, and the acceleration geometry. The recombination measurements on low-lying resonances in lithiumlike Sc{sup 18+} yield a high-precision measurement of the 2s-2p{sub 3/2} transition energy in this system. Operation of the two-electron-beam setup at high collision energy ({approx}1000 eV) is established using resonances of hydrogenlike Mg{sup 11+}, while the unique possibility of modifying the beam-merging geometry con rms its importance for the electron-ion recombination rate at lowest relative energy, as demonstrated on F{sup 6+}. (orig.)

  17. High-resolution electron collision spectroscopy with multicharged ions in merged beams

    International Nuclear Information System (INIS)

    Lestinsky, M.

    2007-01-01

    The Heidelberg ion storage ring Tsr is currently the only ring equipped with two independent devices for the collinear merging of a cold electron beam with stored ions. This greatly improves the potential of electron-ion collision experiments, as the ion beam can be cooled with one electron beam, while the other one is used as a dedicated target for energy-resolved electron collision processes, such as recombination. The work describes the implementation of this system for rst electron collision spectroscopy experiments. A detection system has been realized including an ion detector and specroscopic beam-control software and instrumentation. Moreover, in order to improve the spectroscopic resolution systematical studies of intrinsic relaxation processes in the electron beam have been carried out. These include the dependence on the electron beam density, the magnetic guiding eld strength, and the acceleration geometry. The recombination measurements on low-lying resonances in lithiumlike Sc 18+ yield a high-precision measurement of the 2s-2p 3/2 transition energy in this system. Operation of the two-electron-beam setup at high collision energy (∼1000 eV) is established using resonances of hydrogenlike Mg 11+ , while the unique possibility of modifying the beam-merging geometry con rms its importance for the electron-ion recombination rate at lowest relative energy, as demonstrated on F 6+ . (orig.)

  18. Imagescope to photodiode beam-profile imaging system

    International Nuclear Information System (INIS)

    Chamberlin, D.D.; Hollabaugh, J.S.; Stump, C.J. Jr.

    1983-01-01

    Transverse beam-distribution measurements of high-current cw accelerators must be obtained from noninterceptive sensors. For the 100-mA H 2 or D beam of the Fusion Materials Irradiation Tst (FMIT) accelerator, these transverse properties may be obtained by detecting the visible radiation resulting from beam interactions with residual gas. A system of mirrors, intensified TV cameras, digitizers, and topographic reconstruction codes has been reported previously. This report describes a new technique for sensing and digitizing the light projected transversely from the beam of the FMIT accelerator at Los Alamos National Laboratory

  19. High-resolution compact Johann crystal spectrometer with the Livermore electron beam ion trap

    International Nuclear Information System (INIS)

    Robbins, D.L.; Chen, H.; Beiersdorfer, P.; Faenov, A.Ya.; Pikuz, T.A.; May, M.J.; Dunn, J.; Smith, A.J.

    2004-01-01

    A compact high-resolution (λ/Δλ≅10 000) spherically bent crystal spectrometer in the Johann geometry was recently installed and tested on the Lawrence Livermore National Laboratory SuperEBIT electron beam ion trap. The curvature of the mica (002) crystal grating allows for higher collection efficiency compared to the flat and cylindrically bent crystal spectrometers commonly used on the Livermore electron beam ion traps. The spectrometer's Johann configuration enables orientation of its dispersion plane to be parallel to the electron beam propagation. Used in concert with a crystal spectrometer, whose dispersion plane is perpendicular to the electron beam propagation, the polarization of x-ray emission lines can be measured

  20. Commissioning of a medical accelerator photon beam Monte Carlo simulation using wide-field profiles

    International Nuclear Information System (INIS)

    Pena, J; Franco, L; Gomez, F; Iglesias, A; Lobato, R; Mosquera, J; Pazos, A; Pardo, J; Pombar, M; RodrIguez, A; Sendon, J

    2004-01-01

    A method for commissioning an EGSnrc Monte Carlo simulation of medical linac photon beams through wide-field lateral profiles at moderate depth in a water phantom is presented. Although depth-dose profiles are commonly used for nominal energy determination, our study shows that they are quite insensitive to energy changes below 0.3 MeV (0.6 MeV) for a 6 MV (15 MV) photon beam. Also, the depth-dose profile dependence on beam radius adds an additional uncertainty in their use for tuning nominal energy. Simulated 40 cm x 40 cm lateral profiles at 5 cm depth in a water phantom show greater sensitivity to both nominal energy and radius. Beam parameters could be determined by comparing only these curves with measured data

  1. Commissioning of a medical accelerator photon beam Monte Carlo simulation using wide-field profiles

    Energy Technology Data Exchange (ETDEWEB)

    Pena, J [Departamento de Fisica de PartIculas, Facultade de Fisica, 15782 Santiago de Compostela (Spain); Franco, L [Departamento de Fisica de PartIculas, Facultade de Fisica, 15782 Santiago de Compostela (Spain); Gomez, F [Departamento de Fisica de PartIculas, Facultade de Fisica, 15782 Santiago de Compostela (Spain); Iglesias, A [Departamento de Fisica de PartIculas, Facultade de Fisica, 15782 Santiago de Compostela (Spain); Lobato, R [Hospital ClInico Universitario de Santiago, Santiago de Compostela (Spain); Mosquera, J [Hospital ClInico Universitario de Santiago, Santiago de Compostela (Spain); Pazos, A [Departamento de Fisica de PartIculas, Facultade de Fisica, 15782 Santiago de Compostela (Spain); Pardo, J [Departamento de Fisica de PartIculas, Facultade de Fisica, 15782 Santiago de Compostela (Spain); Pombar, M [Hospital ClInico Universitario de Santiago, Santiago de Compostela (Spain); RodrIguez, A [Departamento de Fisica de PartIculas, Facultade de Fisica, 15782 Santiago de Compostela (Spain); Sendon, J [Hospital ClInico Universitario de Santiago, Santiago de Compostela (Spain)

    2004-11-07

    A method for commissioning an EGSnrc Monte Carlo simulation of medical linac photon beams through wide-field lateral profiles at moderate depth in a water phantom is presented. Although depth-dose profiles are commonly used for nominal energy determination, our study shows that they are quite insensitive to energy changes below 0.3 MeV (0.6 MeV) for a 6 MV (15 MV) photon beam. Also, the depth-dose profile dependence on beam radius adds an additional uncertainty in their use for tuning nominal energy. Simulated 40 cm x 40 cm lateral profiles at 5 cm depth in a water phantom show greater sensitivity to both nominal energy and radius. Beam parameters could be determined by comparing only these curves with measured data.

  2. Ultra-shallow arsenic implant depth profiling using low-energy nitrogen beams

    International Nuclear Information System (INIS)

    Fearn, Sarah; Chater, Richard; McPhail, David

    2004-01-01

    Sputtering of silicon by low-energy nitrogen primary ion beams has been studied by a number of authors to characterize the altered layer, ripple formation and the sputtered yields of secondary ions [Surf. Sci. 424 (1999) 299; Appl. Phys. A: Mater. Sci. Process 53 (1991) 179; Appl. Phys. Lett. 73 (1998) 1287]. This study examines the application of low-energy nitrogen primary ion beams for the possible depth profiling of ultra-shallow arsenic implants into silicon. The emphasis of this work is on the matrix silicon signals in the pre-equilibrium surface region that are used for dose calibration. Problems with these aspects of the concentration depth profiling can give significant inconsistencies well outside the error limits of the quoted dose for the arsenic implantation as independently verified by CV profiling. This occurs during depth profiling with either oxygen primary ion beams (with and without oxygen leaks) or cesium primary ion beams

  3. Gas dynamics considerations in a non-invasive profile monitor for charged particle beams

    CERN Document Server

    Tzoganis, Vasilis; Welsch, Carsten P

    2014-01-01

    A non-invasive, gas jet-based, beam profile monitor has been developed in the QUASAR Group at the Cockcroft Institute, UK. This allows on-line measurement of the 2-dimensional transverse profile of particle beams with negligible disturbance to either primary beam or accelerator vacuum. The monitor is suitable for use with beams across a wide range of energies and intensities. In this setup a nozzle-skimmer system shapes a thin supersonic gas jet into a curtain. However, the small dimensions of the gas inlet nozzle and subsequent skimmers were shown to be the cause of many operational problems. In this paper, the dynamics of gas jet formation transport and shaping is discussed before an image-processing based alignment technique is introduced. Furthermore, experimental results obtained with a 5 keV electron beam are discussed and the effects of gas stagnation pressure on the acquired beam are presented.

  4. A self-calibrating ion beam profiler based on a CsI scintillator

    Energy Technology Data Exchange (ETDEWEB)

    Finocchiaro, P. E-mail: finocchiaro@lns.infn.it; Ciavola, G.; Cosentino, L.; Gu, M.; Raia, G.; Rovelli, A

    1999-11-21

    We report on the test results obtained with a prototype beam profiler based on a thin slit and a CsI scintillator, read out by means of a compact photomultiplier. Such a device has proven to be suitable to perform ion beam diagnostics at low and very low intensities. In particular, our device is suitable for being used in the energy and intensity ranges expected at the EXCYT radioactive ion beam facility, that is currently under development at LNS Catania.

  5. A self-calibrating ion beam profiler based on a CsI scintillator

    International Nuclear Information System (INIS)

    Finocchiaro, P.; Ciavola, G.; Cosentino, L.; Gu, M.; Raia, G.; Rovelli, A.

    1999-01-01

    We report on the test results obtained with a prototype beam profiler based on a thin slit and a CsI scintillator, read out by means of a compact photomultiplier. Such a device has proven to be suitable to perform ion beam diagnostics at low and very low intensities. In particular, our device is suitable for being used in the energy and intensity ranges expected at the EXCYT radioactive ion beam facility, that is currently under development at LNS Catania

  6. Measurement of the density profile of pure and seeded molecular beams by femtosecond ion imaging

    NARCIS (Netherlands)

    Meng, C.; Janssen, M.H.M.

    2015-01-01

    Here, we report on femtosecond ion imaging experiments to measure the density profile of a pulsed supersonic molecular beam. Ion images are measured for both a molecular beam and bulk gas under identical experimental conditions via femtosecond multiphoton ionization of Xe atoms. We report the

  7. Sub-millisecond electron density profile measurement at the JET tokamak with the fast lithium beam emission spectroscopy system

    Science.gov (United States)

    Réfy, D. I.; Brix, M.; Gomes, R.; Tál, B.; Zoletnik, S.; Dunai, D.; Kocsis, G.; Kálvin, S.; Szabolics, T.; JET Contributors

    2018-04-01

    Diagnostic alkali atom (e.g., lithium) beams are routinely used to diagnose magnetically confined plasmas, namely, to measure the plasma electron density profile in the edge and the scrape off layer region. A light splitting optics system was installed into the observation system of the lithium beam emission spectroscopy diagnostic at the Joint European Torus (JET) tokamak, which allows simultaneous measurement of the beam light emission with a spectrometer and a fast avalanche photodiode (APD) camera. The spectrometer measurement allows density profile reconstruction with ˜10 ms time resolution, absolute position calculation from the Doppler shift, spectral background subtraction as well as relative intensity calibration of the channels for each discharge. The APD system is capable of measuring light intensities on the microsecond time scale. However ˜100 μs integration is needed to have an acceptable signal to noise ratio due to moderate light levels. Fast modulation of the beam up to 30 kHz is implemented which allows background subtraction on the 100 μs time scale. The measurement covers the 0.9 background subtraction, the relative calibration, and the comprehensive error calculation, runs a Bayesian density reconstruction code, and loads results to the JET database. The paper demonstrates the capability of the APD system by analyzing fast phenomena like pellet injection and edge localized modes.

  8. Compressive sensing for high resolution profiles with enhanced Doppler performance

    NARCIS (Netherlands)

    Anitori, L.; Hoogeboom, P.; Chevalier, F. Le; Otten, M.P.G.

    2012-01-01

    In this paper we demonstrate how Compressive Sensing (CS) can be used in pulse-Doppler radars to improve the Doppler performance while preserving range resolution. We investigate here two types of stepped frequency waveforms, the coherent frequency bursts and successive frequency ramps, which can be

  9. Application of the inverse estimation method of current distribution from magnetic fields using genetic algorithm to beam profile measurement

    International Nuclear Information System (INIS)

    Kishimoto, M.; Sakasai, K.; Ara, K.

    1994-01-01

    In this paper, the new type of non-invasive beam profile monitor for intense ion accelerator using high-temperature superconductor. We regard the inverse estimation problem of beam profile as the optimum allocation problem of the currents into the cross-section of the beam vacuum pipe and applied genetic algorithm to solve this optimization problem. And we carried out the computer simulation to verify the effectiveness of this inverse estimation method of beam profile. (author)

  10. Design and performance of a high resolution, low latency stripline beam position monitor system

    Directory of Open Access Journals (Sweden)

    R. J. Apsimon

    2015-03-01

    Full Text Available A high-resolution, low-latency beam position monitor (BPM system has been developed for use in particle accelerators and beam lines that operate with trains of particle bunches with bunch separations as low as several tens of nanoseconds, such as future linear electron-positron colliders and free-electron lasers. The system was tested with electron beams in the extraction line of the Accelerator Test Facility at the High Energy Accelerator Research Organization (KEK in Japan. It consists of three stripline BPMs instrumented with analogue signal-processing electronics and a custom digitizer for logging the data. The design of the analogue processor units is presented in detail, along with measurements of the system performance. The processor latency is 15.6±0.1  ns. A single-pass beam position resolution of 291±10  nm has been achieved, using a beam with a bunch charge of approximately 1 nC.

  11. Electron beam excitation assisted optical microscope with ultra-high resolution.

    Science.gov (United States)

    Inami, Wataru; Nakajima, Kentaro; Miyakawa, Atsuo; Kawata, Yoshimasa

    2010-06-07

    We propose electron beam excitation assisted optical microscope, and demonstrated its resolution higher than 50 nm. In the microscope, a light source in a few nanometers size is excited by focused electron beam in a luminescent film. The microscope makes it possible to observe dynamic behavior of living biological specimens in various surroundings, such as air or liquids. Scan speed of the nanometric light source is faster than that in conventional near-field scanning optical microscopes. The microscope enables to observe optical constants such as absorption, refractive index, polarization, and their dynamic behavior on a nanometric scale. The microscope opens new microscopy applications in nano-technology and nano-science.

  12. Calculation of microplanar beam dose profiles in a tissue/lung/tissue phantom

    International Nuclear Information System (INIS)

    Company, F.Z.; Allen, B.J.

    1998-01-01

    Recent advances in synchrotron generated x-ray beams with a high fluence rate permit investigation of the application of an array of closely spaced, parallel or converging microplanar beams in radiotherapy. The proposed technique takes advantage of the hypothesized repair mechanism of capillary cells between alternate microbeam zones, which regenerates the lethally irradiated endothelial cells. The lateral and depth doses of 100 keV microplanar beams are investigated for different beam dimensions and spacings in a tissue, lung and tissue/lung/tissue phantom. The EGS4 Monte Carlo code is used to calculate dose profiles at different depths and bundles of beams (up to 20x20cm square cross section). The maximum dose on the beam axis (peak) and the minimum interbeam dose (valley) are compared at different depths, bundles, heights, widths and beam spacings. (author)

  13. Effects of DTM resolution on slope steepness and soil loss prediction on hillslope profiles

    Science.gov (United States)

    Eder Paulo Moreira; William J. Elliot; Andrew T. Hudak

    2011-01-01

    Topographic attributes play a critical role in predicting erosion in models such as the Water Erosion Prediction Project (WEPP). The effects of four different high resolution hillslope profiles were studied using four different DTM resolutions: 1-m, 3-m, 5-m and 10-m. The WEPP model used a common scenario encountered in the forest environment and the selected hillslope...

  14. Two-dimensional beam-profile monitor using the Reticon MC510A array camera

    International Nuclear Information System (INIS)

    Gottschalk, B.

    1981-08-01

    A quantitative two-dimensional beam profile may be obtained from a scintillator viewed by a Reticon camera which uses a 32 x 32 array of photodiodes as its sensing element. In this note, CAMAC-oriented data acquisition electronics which allow one either to transmit the profile to a computer, or to use the monitor in a stand-alone mode are described

  15. Flatness of two-dimensional beam profile measured with an ionization chamber array

    International Nuclear Information System (INIS)

    Stefanovski, Z.

    2006-01-01

    Open beam profiles are basic dosimetric characteristics for the formation of the dose calculation algorithms parameters and for determination of beam quality. One characteristic of the beam profiles as a measure for the beam quality is the field flatness defined as ratio of the difference of maximum and minimum dose in central 80% of the field to the sum of these doses in the part of the field. The measurements, instead with an ordinary ionization chamber, were performed with a chamber array in two depths (1.6 cm and 10 cm) in water phantom. Nominal photon beam energy was 6 MV and field size was 25 cm x 25 cm on the water surface. Field flatness was in the range of 1-2 % which is in accordance with the data acquired during the acceptance testing and commissioning of the accelerators. with the array chamber the beam profiles can be performed quickly and preciously. These features recommend a chamber array as an excellent tool for periodic quality control of beam profiles. (Author)

  16. Beam preparation system and beam emittance, the essential for high-resolution magnetique spectroscopy

    International Nuclear Information System (INIS)

    Roussel, P.

    1984-01-01

    Using first order calculations derived for an achromatic system A) (delta xsub(F)/delta Esub(i) = 0) or an optimised system 0) (xsub(F) minima), it is shown that the final resolution measured in the focal plane (possibly kinematically displaced) of the spectrometer, depends only on the emittance of the accelerator and of the efficient area of the analyser, exclusive of the properties of the spectrometer. The use of this result is only limited by higher order terms in the calculation, or by considerations out of the scope of this article, like target effects etc.. [fr

  17. Spectral resolution control of acousto-optical cells operating with collimated and divergent beams

    Science.gov (United States)

    Voloshinov, Vitaly B.; Mishin, Dimitry D.

    1994-01-01

    The paper is devoted to theoretical and experimental investigations of acousto-optical interactions in crystals which may be used for spectral filtration of light in tunable acousto- optical filters. Attention is paid to spectral resolution control during operation with divergent or collimated noncoherent optical beams. In all examined cases spectral bands of anisotropic Bragg diffraction were regulated by means of novel electronical methods. Resolution control was achieved in paratellurite cells with non-collinear and quasi-collinear regimes of the diffraction. Filtration spectral bandwidths for visible light were electronically changed by a factor of 10 divided by 20 by drive electrical signals switching and drive electrical power regulations.

  18. Test beam & time resolution analysis for UFSD and CVD diamond detectors

    CERN Document Server

    Scali, Stefano

    2017-01-01

    The ever-increasing luminosity in particle physics, aimed at seeking new phenomena, has led to the need for radiation-hard detectors with a remarkable time resolution. To reach the goal several tests and data analysis has been performed but further development is still required. During my internship I have participated to the test of new sensors. After an introduction to the theoretical framework this report describes the data taking procedure using SPS beam at the H8 site in Prevessin. The second part describes the data analysis and extrapolation of the time resolution for many boards.

  19. Measurement of the density profile of pure and seeded molecular beams by femtosecond ion imaging

    Energy Technology Data Exchange (ETDEWEB)

    Meng, Congsen [LaserLaB Amsterdam, VU University Amsterdam, de Boelelaan 1083, 1081 HV Amsterdam (Netherlands); Department of Physics, National University of Defense Technology, Changsha 410073 (China); Janssen, Maurice H. M. [LaserLaB Amsterdam, VU University Amsterdam, de Boelelaan 1083, 1081 HV Amsterdam (Netherlands)

    2015-02-15

    Here, we report on femtosecond ion imaging experiments to measure the density profile of a pulsed supersonic molecular beam. Ion images are measured for both a molecular beam and bulk gas under identical experimental conditions via femtosecond multiphoton ionization of Xe atoms. We report the density profile of the molecular beam, and the measured absolute density is compared with theoretical calculations of the centre line beam density. Subsequently, we discuss reasons accounting for the differences between measurements and calculations and propose that strong skimmer interference is the most probable cause for the differences. Furthermore, we report on experiments measuring the centre line density of seeded supersonic beams. The femtosecond ion images show that seeding the heavy Xe atom at low relative seed fractions (1%-10%) in a light carrier gas like Ne results in strong relative enhancements of up to two orders of magnitude.

  20. Maximum entropy algorithm and its implementation for the neutral beam profile measurement

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seung Wook; Cho, Gyu Seong [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of); Cho, Yong Sub [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1997-12-31

    A tomography algorithm to maximize the entropy of image using Lagrangian multiplier technique and conjugate gradient method has been designed for the measurement of 2D spatial distribution of intense neutral beams of KSTAR NBI (Korea Superconducting Tokamak Advanced Research Neutral Beam Injector), which is now being designed. A possible detection system was assumed and a numerical simulation has been implemented to test the reconstruction quality of given beam profiles. This algorithm has the good applicability for sparse projection data and thus, can be used for the neutral beam tomography. 8 refs., 3 figs. (Author)

  1. Maximum entropy algorithm and its implementation for the neutral beam profile measurement

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seung Wook; Cho, Gyu Seong [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of); Cho, Yong Sub [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1998-12-31

    A tomography algorithm to maximize the entropy of image using Lagrangian multiplier technique and conjugate gradient method has been designed for the measurement of 2D spatial distribution of intense neutral beams of KSTAR NBI (Korea Superconducting Tokamak Advanced Research Neutral Beam Injector), which is now being designed. A possible detection system was assumed and a numerical simulation has been implemented to test the reconstruction quality of given beam profiles. This algorithm has the good applicability for sparse projection data and thus, can be used for the neutral beam tomography. 8 refs., 3 figs. (Author)

  2. Non-uniformly polarized beams across their transverse profiles: an introductory study for undergraduate optics courses

    International Nuclear Information System (INIS)

    Piquero, Gemma; Vargas-Balbuena, Javier

    2004-01-01

    We provide a simple theoretical study of beams non-uniformly polarized across their transverse sections which can be introduced in undergraduate optics courses. In order to generate such beams we propose to use a slightly convergent (or divergent) linearly and uniformly polarized beam impinging on an anisotropic uniaxial material with the beam propagation direction along the optic axis. Analytical expressions for the Jones vector, Stokes parameters, ellipticity and azimuth at each point of the transverse section, perpendicular to the propagation direction, are obtained at the output of this system. By means of these parameters a detailed description of the state of polarization across the transverse profile is given

  3. High resolution study of the inclusive production of massive muon pairs by intense pion beams

    CERN Multimedia

    2002-01-01

    This experiment measures with high resolution and large acceptance the inclusive production of massive muon pairs with the intense pion beam (up to $10^{10} \\pi/$pulse) in the experimental hall ECN3. The experiment explores extended M$^{2}$/s, x and transverse momentum ranges. The study of the departures of the lepton-pair production cross- section from scaling constitutes a good test of QCD ideas; in the framework of the 'Drell-Yan' process, the experiment allows a detailed study of the pion parton distribution functions. The detector consists of a beam dump, a pulsed toroidal a magnet, MWPC's and scintillator hodoscopes. Its $\\sim 2$% mass resolution at 10 GeV is adequate for the substraction of resonances in the high-mass region.

  4. Ion temperature profiles along a hydrogen diagnostic beam in a TORE SUPRA tokamak plasma

    International Nuclear Information System (INIS)

    Romannikov, A.; Petrov, Yu.; Platts, P.; Khess, V.; Khutter, T.; Farzhon, Zh.; Moro, F.

    2002-01-01

    By means of corpuscular diagnostics one studies temperature of ions along a diagnostic hydrogen beam. Paper presents comparison of temperature of plasma (deuterium) basic ions measures by means of the active corpuscular diagnostics with temperature of C + carbon ions along a beam. One studies behavior peculiarities of T i ion temperature profiles for TORE-SUPRA different modes, such as: formation of plane and even hollow T i profiles for ohmic modes, variation of T i profiles under operation of an ergodic diverter, difference of temperature of basic ions measured by means of the active corpuscular diagnostics from C +5 temperature. Paper offers clear explanation of these peculiarities [ru

  5. High-resolution electron-beam patternable nanocomposite containing metal nanoparticles for plasmonics

    International Nuclear Information System (INIS)

    Abargues, R; Marques-Hueso, J; Canet-Ferrer, J; Pedrueza, E; Valdes, J L; Jimenez, E; MartInez-Pastor, J P

    2008-01-01

    Polymer nanocomposites containing noble metal nanoparticles are promising materials for plasmonic applications. In this paper, we report on a high-resolution negative-tone nanocomposite resist based on poly(vinyl alcohol) where silver nanoparticles and nanopatterns are simultaneously generated by electron-beam lithography. Our results indicate nanostructures with a relatively high concentration of nanoparticles and, consequently, an electromagnetic coupling among the nanoparticles. Therefore, the patternable nanocomposite described in this work may be a suitable material for future plasmonic circuitry

  6. Moving gantry method for electron beam dose profile measurement at extended source-to-surface distances.

    Science.gov (United States)

    Fekete, Gábor; Fodor, Emese; Pesznyák, Csilla

    2015-03-08

    A novel method has been put forward for very large electron beam profile measurement. With this method, absorbed dose profiles can be measured at any depth in a solid phantom for total skin electron therapy. Electron beam dose profiles were collected with two different methods. Profile measurements were performed at 0.2 and 1.2 cm depths with a parallel plate and a thimble chamber, respectively. 108cm × 108 cm and 45 cm × 45 cm projected size electron beams were scanned by vertically moving phantom and detector at 300 cm source-to-surface distance with 90° and 270° gantry angles. The profiles collected this way were used as reference. Afterwards, the phantom was fixed on the central axis and the gantry was rotated with certain angular steps. After applying correction for the different source-to-detector distances and incidence of angle, the profiles measured in the two different setups were compared. Correction formalism has been developed. The agreement between the cross profiles taken at the depth of maximum dose with the 'classical' scanning and with the new moving gantry method was better than 0.5 % in the measuring range from zero to 71.9 cm. Inverse square and attenuation corrections had to be applied. The profiles measured with the parallel plate chamber agree better than 1%, except for the penumbra region, where the maximum difference is 1.5%. With the moving gantry method, very large electron field profiles can be measured at any depth in a solid phantom with high accuracy and reproducibility and with much less time per step. No special instrumentation is needed. The method can be used for commissioning of very large electron beams for computer-assisted treatment planning, for designing beam modifiers to improve dose uniformity, and for verification of computed dose profiles.

  7. Two-photon equivalent weighting of spatial excimer laser beam profiles

    Science.gov (United States)

    Eva, Eric; Bauer, Harry H.; Metzger, K.; Pfeiffer, A.

    2001-04-01

    Damage in optical materials for semiconductor lithography applications caused by exposure to 248 or 193 nm light is usually two-photon driven, hence it is a nonlinear function of incident intensity. Materials should be tested with flat- topped temporal and spatial laser beam profiles to facilitate interpretation of data, but in reality this is hard to achieve. Sandstrom provided a formula that approximates any given temporal pulse shape with a two- photon equivalent rectangular pulse (Second Symposium on 193 nm Lithography, Colorado Springs 1997). Known as the integral-square pulse duration, this definition has been embraced as an industry standard. Originally faced with the problem of comparing results obtained with pseudo-Gaussian spatial profiles to literature data, we found that a general solution for arbitrarily inhomogeneous spatial beam profiles exists which results in a definition much similar to Sandstrom's. In addition, we proved the validity of our approach in experiments with intentionally altered beam profiles.

  8. Beam profile measurement of ES-200 using secondary electron emission monitor

    Directory of Open Access Journals (Sweden)

    E Ebrahimi Basabi

    2015-09-01

    Full Text Available Up to now, different designs have been introduced for measurement beam profile accelerators. Secondary electron emission monitors (SEM are one of these devices which have been used for this purpose. In this work, a SEM has been constructed to measure beam profile of ES-200 accelerator, a proton electrostatic accelerator which is installed at SBU. Profile grid for both planes designed with 16 wires which are insulated relative to each other. The particles with maximum energy of 200 keV and maximum current of 400 μA are stopped in copper wires. Each of the wires has an individual current-to-voltage amplifier. With a multiplexer, the analogue values are transported to an ADC. The ADCs are read out by a microcontroller and finally profile of beam shows by a user interface program

  9. High Resolution Shear Profile Measurements in Entangled Polymers

    KAUST Repository

    Hayes, Keesha A.

    2008-11-17

    We use confocal microscopy and particle image velocimetry to visualize motion of 250-300 nm. fluorescent tracer particles in entangled polymers subject to a rectilinear shear flow. Our results show linear velocity profiles in polymer solutions spanning a wide range of molecular weights and number of entanglements (8≤Z≤56), but reveal large differences between the imposed and measured shear rates. These findings disagree with recent reports that shear banding is a characteristic flow response of entangled polymers, and instead point to interfacial slip as an important source of strain loss. © 2008 The American Physical Society.

  10. Efficient creation of electron vortex beams for high resolution STEM imaging.

    Science.gov (United States)

    Béché, A; Juchtmans, R; Verbeeck, J

    2017-07-01

    The recent discovery of electron vortex beams carrying quantised angular momentum in the TEM has led to an active field of research, exploring a variety of potential applications including the possibility of mapping magnetic states at the atomic scale. A prerequisite for this is the availability of atomic sized electron vortex beams at high beam current and mode purity. In this paper we present recent progress showing that by making use of the Aharonov-Bohm effect near the tip of a long single domain ferromagnetic Nickel needle, a very efficient aperture for the production of electron vortex beams can be realised. The aperture transmits more than 99% of all electrons and provides a vortex mode purity of up to 92%. Placing this aperture in the condenser plane of a state of the art Cs corrected microscope allows us to demonstrate atomic resolution HAADF STEM images with spatial resolution better than 1 Angström, in agreement with theoretical expectations and only slightly inferior to the performance of a non-vortex probe on the same instrument. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. Sub-micron resolution rf cavity beam position monitor system at the SACLA XFEL facility

    Science.gov (United States)

    Maesaka, H.; Ego, H.; Inoue, S.; Matsubara, S.; Ohshima, T.; Shintake, T.; Otake, Y.

    2012-12-01

    We have developed and constructed a C-band (4.760 GHz) rf cavity beam position monitor (RF-BPM) system for the XFEL facility at SPring-8, SACLA. The demanded position resolution of the RF-BPM is less than 1 μm, because an electron beam and x-rays must be overlapped within 4 μm precision in the undulator section for sufficient FEL interaction between the electrons and x-rays. In total, 57 RF-BPMs, including IQ demodulators and high-speed waveform digitizers for signal processing, were produced and installed into SACLA. We evaluated the position resolutions of 20 RF-BPMs in the undulator section by using a 7 GeV electron beam having a 0.1 nC bunch charge. The position resolution was measured to be less than 0.6 μm, which was sufficient for the XFEL lasing in the wavelength region of 0.1 nm, or shorter.

  12. Design of a D-alpha beam-ion profile diagnostic

    International Nuclear Information System (INIS)

    Luo, Y.; Heidbrink, W.W.; Burrell, K.H.

    2004-01-01

    Injected neutral beams ionize to create a population of beam ions. As they orbit around the tokamak and pass through the heating beams, some beam ions re-neutralize and emit D-alpha light. The intensity of this emission is weak compared to the signals from the injected neutrals, the warm (halo) neutrals, and the edge recombination neutrals but, for a favorable viewing geometry, the emission is Doppler shifted away from these bright interfering signals. Preliminary data from the DIII-D tokamak show that signals from re-neutralized beam ions have already been detected. A three-channel prototype instrument consisting of a spectrometer, mask, camera lenses, and frame-transfer charge coupled device is under development for measurements of the spatial profile of the beam ions

  13. Edge electron density profiles and fluctuations measured by two-dimensional beam emission spectroscopy in the KSTAR

    Energy Technology Data Exchange (ETDEWEB)

    Nam, Y. U., E-mail: yunam@nfri.re.kr; Wi, H. M. [National Fusion Research Institute, Daejeon (Korea, Republic of); Zoletnik, S.; Lampert, M. [Wigner RCP Institute for Particle and Nuclear Physics, Budapest (Hungary); Kovácsik, Ákos [Institute of Nuclear Techniques, Budapest Technical University, Budapest (Hungary)

    2014-11-15

    Beam emission spectroscopy (BES) system in Korea Superconducting Tokamak Advanced Research (KSTAR) has recently been upgraded. The background intensity was reduced from 30% to 2% by suppressing the stray lights. This allows acquisition of the relative electron density profiles on the plasma edge without background subtraction from the beam power modulation signals. The KSTAR BES system has its spatial resolution of 1 cm, the temporal resolution of 2 MHz, and a total 32 channel (8 radial × 4 poloidal) avalanche photo diode array. Most measurements were done on the plasma edge, r/a ∼ 0.9, with 8 cm radial measurement width that covers the pedestal range. High speed density profile measurements reveal temporal behaviors of fast transient events, such as the precursors of edge localized modes and the transitions between confinement modes. Low background level also allows analysis of the edge density fluctuation patterns with reduced background fluctuations. Propagation of the density structures can be investigated by comparing the phase delays between the spatially distributed channels.

  14. Non-destructive profile measurement of intensive heavy ion beams; Zerstoerungsfreie Profilmessung intensiver Schwerionenstrahlen

    Energy Technology Data Exchange (ETDEWEB)

    Becker, Frank

    2010-02-08

    Within the framework of the FAIR-project (Facility for Antiproton and Ion Research) at GSI (Helmholtz Center for Heavy Ion Research), high intensity beams from protons to uranium ions with kinetic energies up to 30 AGeV are foreseen. Present GSI-accelerators like the UNILAC and the Heavy Ion Synchrotron (SIS-18) with a magnetic rigidity of 18 Tm will be used as injectors for the future synchrotron (SIS-100). Their beam current will be increased by up to two orders of magnitude. An accurate beam position and beam profile measurement is mandatory for a safe operation of transport sections, in particular in front of production targets (Fragment Separator (FRS)-target, anti p-production-target and Warm Dense Matter (WDM)-targets). Conventional intercepting profile monitors will not withstand the thermal stress of intensive ion beams, particularly for low energy applications or focused beams. For transverse profile determination a non-intercepting Beam Induced Fluorescence (BIF)-monitor was developed, working with residual gas. The BIF-monitor exploits fluorescence light emitted by residual gas molecules after atomic collisions with beam ions. Fluorescence-images were recorded with an image-intensified camera system, and beam profiles were obtained by projecting these images. Within the scope of this dissertation the following topics have been investigated: The photon yield, profile shape and background contribution were determined for different ion species (H{sup +}, S{sup 6+}, Ar{sup 18+}, K{sup +}, Ni{sup 9+}, Xe{sup 48+}, Ta{sup 24+}, Au{sup 65+}, U{sup 73+}), beam energies (7.7 AkeV-750 AMeV), gas pressures (10{sup -6}-3 mbar) and gas species (N{sub 2}, He, Ne, Ar, Kr, Xe). Applying an imaging spectrograph and narrowband 10 nm interference filters, the spectral response was mapped and associated with the corresponding gas transitions. Spectrally resolved beam profiles were also obtained form the spectrographic images. Major results are the light yield showing a

  15. Beam profile monitor system for the bevalac transfer line

    International Nuclear Information System (INIS)

    Stover, G.

    1985-01-01

    Incorporated in the current Bevalac transfer line upgrade project is a proposal for a new electronic beam monitoring system. It will be designed to amplify, convert, and transmit the signals of twelve 16 by 16 multi-wire grids to a central computer located in the Bevatron control room. Each station will contain interface amplifiers and a local microprocessor to convert wire grid currents into digitized values which will then be transmitted via a serial data channel to the main computer. The system will have a large dynamic range (1 nano to 1 milli-ampere of beam current), be designed for distributed operation, and will be easily expandable. This paper describes the basic electronic hardware and software components of the proposed system

  16. Electron temperature profiles in high power neutral-beam-heated TFTR [Tokamak Fusion Test Reactor] plasmas

    International Nuclear Information System (INIS)

    Taylor, G.; Grek, B.; Stauffer, F.J.; Goldston, R.J.; Fredrickson, E.D.; Wieland, R.M.; Zarnstorff, M.C.

    1987-09-01

    In 1986, the maximum neutral beam injection (NBI) power in the Tokamak Fusion Test Reactor (TFTR) was increased to 20 MW, with three beams co-parallel and one counter-parallel to I/sub p/. TFTR was operated over a wide range of plasma parameters; 2.5 19 19 m -3 . Data bases have been constructed with over 600 measured electron temperature profiles from multipoint TV Thomson scattering which span much of this parameter space. We have also examined electron temperature profile shapes from electron cyclotron emission at the fundamental ordinary mode and second harmonic extraordinary mode for a subset of these discharges. In the light of recent work on ''profile consistency'' we have analyzed these temperature profiles in the range 0.3 < (r/a) < 0.9 to determine if a profile shape exists which is insensitive to q/sub cyl/ and beam-heating profile. Data from both sides of the temperature profile [T/sub e/(R)] were mapped to magnetic flux surfaces [T/sub e/(r/a)]. Although T/sub e/(r/a), in the region where 0.3 < r/a < 0.9 was found to be slightly broader at lower q/sub cyl/, it was found to be remarkably insensitive to β/sub p/, to the fraction of NBI power injected co-parallel to I/sub p/, and to the heating profile going from peaked on axis, to hollow. 10 refs., 8 figs

  17. Energy deposition profile on ISOLDE Beam Dumps by FLUKA simulations

    CERN Document Server

    Vlachoudis, V

    2014-01-01

    In this report an estimation of the energy deposited on the current ISOLDE beam dumps obtained by means of FLUKA simulation code is presented. This is done for both ones GPS and HRS. Some estimations of temperature raise are given based on the assumption of adiabatic increase from energy deposited by the impinging protons. However, the results obtained here in relation to temperature are only a rough estimate. They are meant to be further studied through thermomechanical simulations using the energyprofiles hereby obtained.

  18. A Low-cost Beam Profiler Based On Cerium-doped Silica Fibers

    Science.gov (United States)

    Potkins, David Edward; Braccini, Saverio; Nesteruk, Konrad Pawel; Carzaniga, Tommaso Stefano; Vedda, Anna; Chiodini, Norberto; Timmermans, Jacob; Melanson, Stephane; Dehnel, Morgan Patrick

    A beam profiler called the Universal Beam Monitor (UniBEaM) has been developed by D-Pace Inc. (Canada) and the Albert Einstein Center for Fundamental Physics, Laboratory for High Energy Physics, University of Bern (Switzerland). The device is based on passing 100 to 600 micron cerium-doped optical fibers through a particle beam. Visible scintillation light from the sensor fibers is transmitted over distances of tens of meters to the light sensors with minimal signal loss and no susceptibility to electromagnetic fields. The probe has an insertion length of only 70 mm. The software plots the beam intensity distribution in the horizontal and vertical planes, and calculates the beam location and integrated profile area, which correlates well with total beam current. UniBEaM has a large dynamic range, operating with beam currents of ∼pA to mA, and a large range of particle kinetic energies of ∼keV to GeV, depending on the absorbed power density. Test data are presented for H- beams at 25keV for 500 μA, and H+ beams at 18MeV for 50pA to 10 μA. Maximum absorbed power density of the optical fiber before thermal damage is discussed in relation to dE/dx energy deposition as a function of particle type and kinetic energy. UniBEaM is well suited for a wide variety of beamlines including discovery science applications, radio-pharmaceutical production, hadron therapy, industrial ion beam applications including ion implantation, industrial electron beams, and ion source testing.

  19. Using elastic peak electron spectroscopy for enhanced depth resolution in sputter profiling

    International Nuclear Information System (INIS)

    Hofmann, S.; Kesler, V.

    2002-01-01

    Elastic peak electron spectroscopy (EPES) is an alternative to AES in sputter depth profiling of thin film structures. In contrast to AES, EPES depth profiling is not influenced by chemical effects. The high count rate ensures a good signal to noise ratio, that is lower measurement times and/or higher precision. In addition, because of the elastically scattered electrons travel twice through the sample, the effective escape depth is reduced, an important factor for the depth resolution function. Thus, the depth resolution is increased. EPES depth profiling was successfully applied to a Ge/Si multilayer structure. For an elastic peak energy of 1.0 keV the information depth is considerably lower (0.8 nm) as compared to the Ge (LMM, 1147 eV) peak (1.6 nm) used in AES depth profiling, resulting in a respectively improved depth resolution for EPES profiling under otherwise similar profiling conditions. EPES depth profiling is successfully applied to measure small diffusion lengths at Ge/Si interfaces of the order of 1 nm. (Authors)

  20. Depth profile analysis of thin TiOxNy films using standard ion beam analysis techniques and HERDA

    International Nuclear Information System (INIS)

    Markwitz, A.; Dytlewski, N.; Cohen, D.

    1999-01-01

    Ion beam assisted deposition is used to fabricate thin titanium oxynitride films (TiO x N y ) at Industrial Research (typical film thickness 100nm). At the Institute of Geological and Nuclear Sciences, the thin films are analysed using non-destructive standard ion beam analysis (IBA) techniques. High-resolution titanium depth profiles are measured with RBS using 1.5MeV 4 He + ions. Non-resonant nuclear reaction analysis (NRA) is performed for investigating the amounts of O and N in the deposited films using the reactions 16 O(d,p) 17 O at 920 keV and 14 N(d,α) 12 C at 1.4 MeV. Using a combination of these nuclear techniques, the stoichiometry as well as the thickness of the layers is revealed. However, when oxygen and nitrogen depth profiles are required for investigating stoichiometric changes in the films, additional nuclear analysis techniques such as heavy ion elastic recoil detection (HERDA) have to be applied. With HERDA, depth profiles of N, O, and Ti are measured simultaneously. In this paper comparative IBA measurement s of TiO x N y films with different compositions are presented and discussed

  1. Raw ODEC Bathy2000 CHIRP subbottom profiler - CHIRP high-resolution Seismic Profile data for the U.S. Arctic Continental Margin.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — ODEC Bathy2000 CHIRP subbottom profiler - CHIRP high-resolution Seismic Profile data were collected in Raw ODEC Bathy2000 CHIRP dat Datagram Format.

  2. Raw ODEC Bathy2000 CHIRP subbottom profiler - CHIRP high-resolution Seismic Profile data for the Chukchi Cap and Arctic Ocean.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — ODEC Bathy2000 CHIRP subbottom profiler - CHIRP high-resolution Seismic Profile data were collected in Raw ODEC Bathy2000 CHIRP dat Datagram Format.

  3. Statistically sound evaluation of trace element depth profiles by ion beam analysis

    International Nuclear Information System (INIS)

    Schmid, K.; Toussaint, U. von

    2012-01-01

    This paper presents the underlying physics and statistical models that are used in the newly developed program NRADC for fully automated deconvolution of trace level impurity depth profiles from ion beam data. The program applies Bayesian statistics to find the most probable depth profile given ion beam data measured at different energies and angles for a single sample. Limiting the analysis to % level amounts of material allows one to linearize the forward calculation of ion beam data which greatly improves the computation speed. This allows for the first time to apply the maximum likelihood approach to both the fitting of the experimental data and the determination of confidence intervals of the depth profiles for real world applications. The different steps during the automated deconvolution will be exemplified by applying the program to artificial and real experimental data.

  4. Mission profile resolution effects on lifetime estimation of doubly-fed induction generator power converter

    DEFF Research Database (Denmark)

    Zhang, Guanguan; Zhou, Dao; Blaabjerg, Frede

    2017-01-01

    , and the corresponding thermal modeling of power semiconductors are discussed. Accordingly, effects of different mission profiles on the consumed lifetime of the power converter are evaluated. In the above three thermal cycles, the IGBT of the grid-side converter and the diode of the rotor-side converter are more...... fragile, and the total consumed lifetimes are higher. Moreover, the short-term thermal cycles with milliseconds resolution induce the unbalance of the lifetime between the diode and IGBT of the grid-side converter, while thermal cycles with hour, second, and millisecond resolution consumes the similar......In the wind energy generation system, mission profiles are complicated, which range from seconds to years. In order to estimate the consumed lifetime of the power converter, wind speed profiles with the time resolution of 1 hour, 1 second and 0.5 millisecond are studied in this paper...

  5. Introduction to analytical techniques of beam-target interactions and resolutions

    International Nuclear Information System (INIS)

    Ruste, J.

    1995-08-01

    For several years, new analysis and observation techniques have been developed, which have considerably improved material research. Almost all these techniques are based on the interaction of a beam of 'primary particles' (electrons, photons, ions, particles, etc) with target. Correct and appropriate use of these techniques requires a good knowledge of these interactions and their consequences (emissions of 'secondary particles', modifications of the primary beam and target, etc). The first part of this report deals with the radiation/material interactions according to the nature of the radiation and its energy. The nature and consequences of the interaction of an electromagnetic wave, a beam of electrons, ions and neutrons are examined over an extended range of energy from MeV to MeV. Certain notions such as the analysis area, spatial resolutions or limits of detection can also be defined. In the second part, some of the most important and widespread techniques of analysis and observation are compared in terms of properties and performance. In particular, there is a brief principle of the technique, nature of the data obtained, spatial resolution, and the limits of detection with today's methods permit. (author). 5 refs., 23 figs., 9 tabs

  6. Online diagnostics of time-resolved electron beam properties with femtosecond resolution for X-ray FELs

    International Nuclear Information System (INIS)

    Yan, Minjie

    2016-07-01

    The European X-ray Free-electron Laser (XFEL) puts high demands on the quality of the highbrightness driving electron beam with bunch lengths in the femtosecond regime. Longitudinal diagnostics is requested to optimize and control the longitudinal profile, the longitudinal phase space, the slice energy spread and the slice emittance of the electron bunch, all of which are crucial to the generation of Self-Amplified Spontaneous Emission (SASE). The high bunch repetition rate of the super-conducting accelerator renders diagnostic method that is (quasi) non-destructive to the generation of SASE possible. In this thesis, three online diagnostic sections utilizing transverse deflecting structures (TDS) have been designed for the European XFEL, providing access to all parameters of interest with a longitudinal resolution down to below 10 fs.The requirement on the non-destructive capability has been realized by the implementation of fast kickermagnets and off-axis screens, which has been validated experimentally using an installation of the same concept at the Free-electron Laser in Hamburg. A special slicing procedure has been developed to significantly enhance the accuracy of slice energy spread measurements. Suppression of coherence effects, which impede the beam imaging in the TDS diagnostics, has been first demonstrated experimentally using the spatial separation method with scintillator screens. Comparison of the results of emittance measurements using the quadrupole scan method with those using the multi-screen method has proved the reliability of the latter method, which has been modelled intensively for the European XFEL.

  7. The measurement of neutral beam thermal profiles on 'V'-shaped calorimeters

    International Nuclear Information System (INIS)

    Kamperschroer, J.H.; Lagin, L.J.; Silber, K.

    1995-01-01

    It is customary in high power neutral beam systems to use a V-shaped calorimeter to stop and measure the beam. With proper instrumentation, it is possible to determine both the neutral beam power and divergence. By utilizing a near-grazing angle of incidence, the area over which the beam is in contact with the surface is increased, thereby decreasing the power density over the case of normal incidence. Thermocouples on the back of the calorimeter, in conjunction with real time fitting algorithms, are used to deduce the divergence from the thermal profile. This measurement implicitly assumes that the measured profile corresponds to that of the incident beam. It is shown that such is not the case. Energetic particle reflection at near-grazing angle causes the thermal profile on the calorimeter to be more peaked than the incident distribution. The implications of this on the non-linear multiple regression technique of determining the divergence are discussed. With the aid of a reflection model, developed and applied to the beam from a typical TFTR ion source, it is shown that a peaked power density can be modelled. Neural networks are being studied as a means of supplanting the older regression technique of measuring divergence. Y-direction divergences have been successfully derived using a one-dimensional neural network

  8. High resolution measurement of the velocity profiles of channel flows using the particle image velocimetry technique

    International Nuclear Information System (INIS)

    Nor Azizi Mohamed

    2000-01-01

    The high resolution velocity profiles of a uniform steady channel flow and a flow beneath waves were obtained using the particle image velocimetry (PIV) technique. The velocity profiles for each flow were calculated for both components. It is shown that the profiles obtained are very precise, displaying the point velocities from a few millimeters from the bottom of the channel up to the water surface across the water depth. In the case of the wave-induced flow, the profiles are shown under the respective wave phases and given in a plane representation. High resolution measurement of point velocities in a flow is achievable using PIV and invaluable when applied to a complex flow. (Author)

  9. SYSTEMATIC ERROR REDUCTION: NON-TILTED REFERENCE BEAM METHOD FOR LONG TRACE PROFILER

    International Nuclear Information System (INIS)

    QIAN, S.; QIAN, K.; HONG, Y.; SENG, L.; HO, T.; TAKACS, P.

    2007-01-01

    Systematic error in the Long Trace Profiler (LTP) has become the major error source as measurement accuracy enters the nanoradian and nanometer regime. Great efforts have been made to reduce the systematic error at a number of synchrotron radiation laboratories around the world. Generally, the LTP reference beam has to be tilted away from the optical axis in order to avoid fringe overlap between the sample and reference beams. However, a tilted reference beam will result in considerable systematic error due to optical system imperfections, which is difficult to correct. Six methods of implementing a non-tilted reference beam in the LTP are introduced: (1) application of an external precision angle device to measure and remove slide pitch error without a reference beam, (2) independent slide pitch test by use of not tilted reference beam, (3) non-tilted reference test combined with tilted sample, (4) penta-prism scanning mode without a reference beam correction, (5) non-tilted reference using a second optical head, and (6) alternate switching of data acquisition between the sample and reference beams. With a non-tilted reference method, the measurement accuracy can be improved significantly. Some measurement results are presented. Systematic error in the sample beam arm is not addressed in this paper and should be treated separately

  10. Influence of micromachined targets on laser accelerated proton beam profiles

    Science.gov (United States)

    Dalui, Malay; Permogorov, Alexander; Pahl, Hannes; Persson, Anders; Wahlström, Claes-Göran

    2018-03-01

    High intensity laser-driven proton acceleration from micromachined targets is studied experimentally in the target-normal-sheath-acceleration regime. Conical pits are created on the front surface of flat aluminium foils of initial thickness 12.5 and 3 μm using series of low energy pulses (0.5-2.5 μJ). Proton acceleration from such micromachined targets is compared with flat foils of equivalent thickness at a laser intensity of 7 × 1019 W cm-2. The maximum proton energy obtained from targets machined from 12.5 μm thick foils is found to be slightly lower than that of flat foils of equivalent remaining thickness, and the angular divergence of the proton beam is observed to increase as the depth of the pit approaches the foil thickness. Targets machined from 3 μm thick foils, on the other hand, show evidence of increasing the maximum proton energy when the depths of the structures are small. Furthermore, shallow pits on 3 μm thick foils are found to be efficient in reducing the proton beam divergence by a factor of up to three compared to that obtained from flat foils, while maintaining the maximum proton energy.

  11. Fast-scan monitor examines neutral-beam ion-density profile

    International Nuclear Information System (INIS)

    Anon.

    1978-01-01

    All of the magnetic mirror confinement fusion experiments at LLL and at other laboratories depend on pulsed, energetic neutral-beam injection for fueling and imparting energy to the trapped plasma for density build-up and stability studies. It is vital to be able to monitor how well the injected ion beam is aimed and focused. To do this, we have designed an ion-beam current-density profile monitor that uses a commercial minimodular data acquisition system. Our prototype model monitors a single 20-kV, 50-A, 10-ms beam. However, the method is applicable to any number of beams with similar sampling target arrays. Also, the electronics can be switched to monitor any one of several target collectors

  12. INFLUENCE OF LASER BEAM PROFILE ON LIGHT SCATTERING BY HUMAN SKIN DURING PHOTOMETRY BY ELLIPSOIDAL REFLECTORS

    Directory of Open Access Journals (Sweden)

    M. A. Bezuglyi

    2018-01-01

    Full Text Available The correct accounting of laser emitter parameters for improvement of diagnostic authenticity of methods of optical biomedical diagnostic is important problem for applied biophotonic tasks. The purpose of the current research is estimation of influence of energy distribution profile in transversal section of laser beam on light scattering by human skin layers at photometry by ellipsoidal reflectors.Biomedical photometer with ellipsoidal reflectors for investigation of biological tissue specimens in transmitted and reflected light uses laser probing radiation with infinitely thin, Gauss-type and uniform cross-section profile. Distribution of beams with denoted profiles, which consist of 20 million photons with wavelength 632.8 nm, was modeled by using of Monte-Carlo simulation in human skin layers (corneous layer, epidermis, derma and adipose tissue of various anatomic thickness and with ellipsoidal reflectors with focal parameter equal to 16.875 mm and eccentricity of 0.66.The modeling results represent that illuminance distribution in zones of photometric imaging is significantly influenced by the laser beam cross-section profile for various thickness of corneous layer and epidermis in transmitted and reflected light, and also derma in reflected light. Illuminance distribution for adipose tissue in reflected and transmitted light, and also derma in transmitted light, practically do not depend of laser beam profile for anatomic thicknesses, which are appropriate for human skin on various sections of body.There are represented results of modified Monte-Carlo simulation method for biomedical photometer with ellipsoidal reflectors during biometry of human skin layers. For highly scattered corneous layer and epidermis the illumination of middle and external rings of photometric images changes depending from the laser beam profile for more than 50 % in transmitted and 30 % in reflected light. For weakly scattering skin layers (derma and adipose layer

  13. Analisis Elektron Beam Profile Constancy pada Pesawat Linac

    Directory of Open Access Journals (Sweden)

    Edi Guritna

    2018-02-01

    Full Text Available Radioterapi adalah pengobatan penyakit terutama tumor atau kanker ganas dengan menggunakan radiasi elektromagnetik (Sinar-X dan Gamma dan radiasi partikel (elektron, proton, dan neutron. Salah satu alat radioterapi modern yang digunakan dalam pengobatan penyakit kanker adalah linear accelerator (linac. Alat radioterapi ini menghasilkan elektron dan sinar-X (foton yang dibangkitkan oleh generator dan mempunyai energi yang bervariasi. Dalam penelitian profil dosis, digunakan pesawat liner accelerator (linac Siemens Primus berkas elektron 5 MeV dengan luas lapangan radiasi berkisar dari 5×5 cm2 sampai 25×25 cm2. Pengukuran profil dosis dilakukan dengan menggunakan water phantom,  detektor farmer chamber dan condenser chamber yang dilengkapi dengan  computer control units (CCU serta dilakukan untuk arah crossline dan inline pada kedalaman Dmax dan kedalaman tertentu. Penelitian ini bertujuan untuk menganalisis profil berkas sinar elektron energi 5 MeV pada kedalaman tertentu dan Dmax dengan variasi luas lapangan 5×5 cm2, 10×10 cm2, 15×15 cm2, 20×20 cm2, 25×25 cm2. Hasil analisis profil dosis pada berkas elektron 5 MeV menunjukkan bahwa lapangan 5×5 cm2 memiliki nilai flatness yang cukup besar sehingga dalam kalibrasi maupun terapi radiasi perlu diperhatikan penggunaan  luas lapangan tersebut. Dalam penelitian ini juga didapatkan bahwa nilai flatness paling ideal (nilai flatness rendah terjadi pada lapangan 15×15 cm2. Sehingga ada luas lapangan lain yang bisa digunakan untuk treatment maupun kalibrasi selain 10×10 cm2 yaitu 15×15 cm2 yang memiliki nilai flatness rendah.

  14. Effect of 3D Polarization profiles on polarization measurements and colliding beam experiments

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, W.; Bazilevsky, A.

    2011-08-18

    The development of polarization profiles are the primary reason for the loss of average polarization. Polarization profiles have been parametrized with a Gaussian distribution. We derive the effect of 3-dimensional polarization profiles on the measured polarization in polarimeters, as well as the observed polarization and the figure of merit in single and double spin experiments. Examples from RHIC are provided. The Relativistic Heavy Ion Collider (RHIC) is the only collider of spin polarized protons. During beam acceleration and storage profiles of the polarization P develop, which affect the polarization measured in a polarimeter, and the polarization and figure of merit (FOM) in colliding beam experiments. We calculate these for profiles in all dimensions, and give examples for RHIC. Like in RHIC we call the two colliding beams Blue and Yellow. We use the overbar to designate intensity-weighted averages in polarimeters (e.g. {bar P}), and angle brackets to designate luminosity-weighted averages in colliding beam experiments (e.g.

    ).

  15. Effect of 3D Polarization profiles on polarization measurements and colliding beam experiments

    International Nuclear Information System (INIS)

    Fischer, W.; Bazilevsky, A.

    2011-01-01

    The development of polarization profiles are the primary reason for the loss of average polarization. Polarization profiles have been parametrized with a Gaussian distribution. We derive the effect of 3-dimensional polarization profiles on the measured polarization in polarimeters, as well as the observed polarization and the figure of merit in single and double spin experiments. Examples from RHIC are provided. The Relativistic Heavy Ion Collider (RHIC) is the only collider of spin polarized protons. During beam acceleration and storage profiles of the polarization P develop, which affect the polarization measured in a polarimeter, and the polarization and figure of merit (FOM) in colliding beam experiments. We calculate these for profiles in all dimensions, and give examples for RHIC. Like in RHIC we call the two colliding beams Blue and Yellow. We use the overbar to designate intensity-weighted averages in polarimeters (e.g. (bar P)), and angle brackets to designate luminosity-weighted averages in colliding beam experiments (e.g. ).

  16. The Study of a Beam Profile Monitor based on Faraday Cup Array

    Energy Technology Data Exchange (ETDEWEB)

    Park, K. M.; Park, S. H.; Kim, S. G.; Kwon, H. J.; Cho, Y. S. [KAERI, Daejeon (Korea, Republic of)

    2015-05-15

    The metal can then be discharged to measure a small current equivalent to the number of impinging ions. The beam current can be measured and used to determine the number of ions or electrons hitting the cup. Recently, beam profile monitor (BPM) based on Faraday cup array (FCA), which represented beam position through the spatial and temporal distribution of the beam current, has been studied due to advantages of measure of wide-range ion beam current. FCA system is divided into a FC, an electrical circuit and display parts. We have studied FCA to monitor beam profile on an electrostatic accelerator with wide-range ion current. In this paper, we represented basic characteristics and designs for the fabricated FCA. FCA system, which consisted of FC system, electronic readout system, and output display, was suggested to measure ion beam current, efficiently. FC system consisted of a collimator, suppressor, tiny FC, insulator frame, and circuit board divided into elec PCB, cap PCB, and con PCB. FC size was 4 mm diameters and FCA system was considered as 8 x 8 array and whole size of 8 x 8 mm''2. FCA system was set-up in vacuum chamber and an integrator and output display parts were formed out of chamber to minimize number of feed-through.

  17. Wide Band and Wide Azimuth Beam Effect on High-resolution Synthetic Aperture Radar Radiometric Calibration

    Directory of Open Access Journals (Sweden)

    Hong Jun

    2015-06-01

    Full Text Available Passive corner reflectors and active transponders are often used as man-made reference targets in Synthetic Aperture Radar (SAR radiometric calibration, With the emergence of new radar systems and the increasing demand for greater accuracy, wide-band and wide-beam radars challenge the hypothesis that the Radar Cross Section (RCS of reference targets is constant. In this study, the FEKO electromagnetic simulation software is used to obtain the change curve of the target RCS as a function of frequency and aspect angle while incorporating high-resolution point-target SAR simulation, and quantitatively analyzing the effect of the modulation effect on SAR images. The simulation results suggest that the abovementioned factors affect the SAR calibration by more than 0.2 dB within a fractional bandwidth greater than 10% or azimuth beam width of more than 20°, which must be corrected in the data processing.

  18. Development of residual gas ionization profile monitor for high intensity proton beams

    CERN Document Server

    Sato, Y; Hirose, E; Ieiri, M; Igarashi, Y; Inaba, S; Katoh, Y; Minakawa, M; Noumi, H; Saitó, M; Suzuki, Y; Takahashi, H; Takasaki, M; Tanaka, K; Toyoda, A; Yamada, Y; Yamanoi, Y; Watanabe, H

    2006-01-01

    Nondestructive beam profile monitor utilizing ionizations of residual gas has been developed for continuous monitoring of 3?0(J-PARC). Knock-on electrons produced in the ionizations of residual gas vacuumed to 1 Pa are collected with a uniform electric field applied between electrodes. Applying a uniform electric field parallel to the electric field is essential to reduce diffusion of electrons crossing over magnetic flux. A prototype monitor has been constructed and installed in EP2-C beam line at KEK 12 GeV proton synchrotron (12 Ge V-PS). The profiles measured with the present monitor agree with the ones measured with the existing destructive profile monitor. The present monitor shows sufficient performances as a candidate of the profile monitor at J-PARC. In the present article, the working principle of the present monitor, the results of test experiments, and further developments are described in detail.

  19. A neutral-beam profile monitor with a phosphor screen and a high-sensitivity camera for the J-PARC KOTO experiment

    Science.gov (United States)

    Matsumura, T.; Kamiji, I.; Nakagiri, K.; Nanjo, H.; Nomura, T.; Sasao, N.; Shinkawa, T.; Shiomi, K.

    2018-03-01

    We have developed a beam-profile monitor (BPM) system to align the collimators for the neutral beam-line at the Hadron Experimental Facility of J-PARC. The system is composed of a phosphor screen and a CCD camera coupled to an image intensifier mounted on a remote control X- Y stage. The design and detailed performance studies of the BPM are presented. The monitor has a spatial resolution of better than 0.6 mm and a deviation from linearity of less than 1%. These results indicate that the BPM system meets the requirements to define collimator-edge positions for the beam-line tuning. Confirmation using the neutral beam for the KOTO experiment is also presented.

  20. Temperature profiles on the gadolinium surface during electron beam evaporation

    Energy Technology Data Exchange (ETDEWEB)

    Ohba, Hironori; Shibata, Takemasa [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1995-03-01

    The distributions of surface temperature of gadolinium in a water-cooled copper crucible during electron beam evaporation were measured by optical pyrometry. The surface temperatures were obtained from the radiation intensity ratio of the evaporating surface and a reference light source using Planck`s law of radiation. The emitted radiation from the evaporating surface and a reference source was detected by a CCD sensor through a band pass filter of 650 nm. The measured surface temperature generally agreed with those estimated from the deposition rate and the data of the saturated vapor pressure. At high input powers, it was found that the measured value had small difference with the estimated one due to variation of the surface condition. (author).

  1. Temperature profiles on the gadolinium surface during electron beam evaporation

    International Nuclear Information System (INIS)

    Ohba, Hironori; Shibata, Takemasa

    1995-01-01

    The distributions of surface temperature of gadolinium in a water-cooled copper crucible during electron beam evaporation were measured by optical pyrometry. The surface temperatures were obtained from the radiation intensity ratio of the evaporating surface and a reference light source using Planck's law of radiation. The emitted radiation from the evaporating surface and a reference source was detected by a CCD sensor through a band pass filter of 650 nm. The measured surface temperature generally agreed with those estimated from the deposition rate and the data of the saturated vapor pressure. At high input powers, it was found that the measured value had small difference with the estimated one due to variation of the surface condition. (author)

  2. High resolution time-of-flight spectrometer for crossed molecular beam study of elementary chemical reactions

    International Nuclear Information System (INIS)

    Qiu Minghui; Che Li; Ren Zefeng; Dai Dongxu; Wang Xiuyan; Yang Xueming

    2005-01-01

    In this article, we describe an apparatus in our laboratory for investigating elementary chemical reactions using the high resolution time-of-flight Rydberg tagging method. In this apparatus, we have adopted a rotating source design so that collision energy can be changed for crossed beam studies of chemical reactions. Preliminary results on the HI photodissociation and the F atom reaction with H 2 are reported here. These results suggest that the experimental apparatus is potentially a powerful tool for investigating state-to-state dynamics of elementary chemical reactions

  3. High resolution kinetic beam schemes in generalized coordinates for ideal quantum gas dynamics

    International Nuclear Information System (INIS)

    Shi, Yu-Hsin; Huang, J.C.; Yang, J.Y.

    2007-01-01

    A class of high resolution kinetic beam schemes in multiple space dimensions in general coordinates system for the ideal quantum gas is presented for the computation of quantum gas dynamical flows. The kinetic Boltzmann equation approach is adopted and the local equilibrium quantum statistics distribution is assumed. High-order accurate methods using essentially non-oscillatory interpolation concept are constructed. Computations of shock wave diffraction by a circular cylinder in an ideal quantum gas are conducted to illustrate the present method. The present method provides a viable means to explore various practical ideal quantum gas flows

  4. High resolution humidity, temperature and aerosol profiling with MeteoSwiss Raman lidar

    Science.gov (United States)

    Dinoev, Todor; Arshinov, Yuri; Bobrovnikov, Sergei; Serikov, Ilya; Calpini, Bertrand; van den Bergh, Hubert; Parlange, Marc B.; Simeonov, Valentin

    2010-05-01

    Meteorological services rely, in part, on numerical weather prediction (NWP). Twice a day radiosonde observations of water vapor provide the required data for assimilation but this time resolution is insufficient to resolve certain meteorological phenomena. High time resolution temperature profiles from microwave radiometers are available as well but have rather low vertical resolution. The Raman LIDARs are able to provide temperature and humidity profiles with high time and range resolution, suitable for NWP model assimilation and validation. They are as well indispensible tools for continuous aerosol profiling for high resolution atmospheric boundary layer studies. To improve the database available for direct meteorological applications the Swiss meteo-service (MeteoSwiss), the Swiss Federal Institute of Technology in Lausanne (EPFL) and the Swiss National Science Foundation (SNSF) initiated a project to design and build an automated Raman lidar for day and night vertical profiling of tropospheric water vapor with the possibility to further upgrade it with an aerosol and temperature channels. The project was initiated in 2004 and RALMO (Raman Lidar for meteorological observations) was inaugurated in August 2008 at MeteoSwiss aerological station at Payerne. RALMO is currently operational and continuously profiles water vapor mixing ratio, aerosol backscatter ratio and aerosol extinction. The instrument is a fully automated, self-contained, eye-safe Raman lidar operated at 355 nm. Narrow field-of-view multi-telescope receiver and narrow band detection allow day and night-time vertical profiling of the atmospheric humidity. The rotational-vibrational Raman lidar responses from water vapor and nitrogen are spectrally separated by a high-throughput fiber coupled diffraction grating polychromator. The elastic backscatter and pure-rotational Raman lidar responses (PRR) from oxygen and nitrogen are spectrally isolated by a double grating polychromator and are used to

  5. Depth resolution and preferential sputtering in depth profiling of sharp interfaces

    International Nuclear Information System (INIS)

    Hofmann, S.; Han, Y.S.; Wang, J.Y.

    2017-01-01

    Highlights: • Interfacial depth resolution from MRI model depends on sputtering rate differences. • Depth resolution critically depends on the dominance of roughness or atomic mixing. • True (depth scale) and apparent (time scale) depth resolutions are different. • Average sputtering rate approximately yields true from apparent depth resolution. • Profiles by SIMS and XPS are different but similar to surface concentrations. - Abstract: The influence of preferential sputtering on depth resolution of sputter depth profiles is studied for different sputtering rates of the two components at an A/B interface. Surface concentration and intensity depth profiles on both the sputtering time scale (as measured) and the depth scale are obtained by calculations with an extended Mixing-Roughness-Information depth (MRI)-model. The results show a clear difference for the two extreme cases (a) preponderant roughness and (b) preponderant atomic mixing. In case (a), the interface width on the time scale (Δt(16–84%)) increases with preferential sputtering if the faster sputtering component is on top of the slower sputtering component, but the true resolution on the depth scale (Δz(16–84%)) stays constant. In case (b), the interface width on the time scale stays constant but the true resolution on the depth scale varies with preferential sputtering. For similar order of magnitude of the atomic mixing and the roughness parameters, a transition state between the two extremes is obtained. While the normalized intensity profile of SIMS represents that of the surface concentration, an additional broadening effect is encountered in XPS or AES by the influence of the mean electron escape depth which may even cause an additional matrix effect at the interface.

  6. Depth resolution and preferential sputtering in depth profiling of sharp interfaces

    Energy Technology Data Exchange (ETDEWEB)

    Hofmann, S. [Max Planck Institute for Intelligent Systems (formerly MPI for Metals Research), Heisenbergstrasse 3, D-70569 Stuttgart (Germany); Han, Y.S. [Department of Physics, Shantou University, 243 Daxue Road, Shantou, 515063 Guangdong (China); Wang, J.Y., E-mail: wangjy@stu.edu.cn [Department of Physics, Shantou University, 243 Daxue Road, Shantou, 515063 Guangdong (China)

    2017-07-15

    Highlights: • Interfacial depth resolution from MRI model depends on sputtering rate differences. • Depth resolution critically depends on the dominance of roughness or atomic mixing. • True (depth scale) and apparent (time scale) depth resolutions are different. • Average sputtering rate approximately yields true from apparent depth resolution. • Profiles by SIMS and XPS are different but similar to surface concentrations. - Abstract: The influence of preferential sputtering on depth resolution of sputter depth profiles is studied for different sputtering rates of the two components at an A/B interface. Surface concentration and intensity depth profiles on both the sputtering time scale (as measured) and the depth scale are obtained by calculations with an extended Mixing-Roughness-Information depth (MRI)-model. The results show a clear difference for the two extreme cases (a) preponderant roughness and (b) preponderant atomic mixing. In case (a), the interface width on the time scale (Δt(16–84%)) increases with preferential sputtering if the faster sputtering component is on top of the slower sputtering component, but the true resolution on the depth scale (Δz(16–84%)) stays constant. In case (b), the interface width on the time scale stays constant but the true resolution on the depth scale varies with preferential sputtering. For similar order of magnitude of the atomic mixing and the roughness parameters, a transition state between the two extremes is obtained. While the normalized intensity profile of SIMS represents that of the surface concentration, an additional broadening effect is encountered in XPS or AES by the influence of the mean electron escape depth which may even cause an additional matrix effect at the interface.

  7. High flux and high resolution VUV beam line for synchrotron radiation

    International Nuclear Information System (INIS)

    Wilcke, H.; Boehmer, W.; Schwentner, N.

    1982-04-01

    A beam line has been optimized for high flux and high resolution in the wavelength range from 30 nm to 300 nm. Sample chambers for luminescence spectroscopy on gaseous, liquid and solid samples and for photoelectron spectroscopy have been integrated. The synchrotron radiation from the storage ring DORIS (at DESY, Hamburg) emitted into 50 mrad in horizontal and into 2.2 mrad in vertical direction is focused by a cylindrical and a plane elliptical mirror into the entrance slit of a 2m normal incidence monochromator. The light flux from the exit slit is focused by a rotational elliptic mirror onto the sample yielding a size of the light spot of 4 x 0.15 mm 2 . The light flux at the sample reaches 7 x 10 12 photons nm -1 s -1 at 8 eV photon energy for a current of 100 mA in DORIS. A resolution of 0.007 nm has been obtained. (orig.)

  8. Resolution Studies at Beam Position Monitors at the FLASH Facility at DESY

    Science.gov (United States)

    Baboi, N.; Lund-Nielsen, J.; Noelle, D.; Riesch, W.; Traber, T.; Kruse, J.; Wendt, M.

    2006-11-01

    More than 60 beam position monitors (BPM) are installed along about 350m of beamline of the Free Electron LASer in Hamburg (FLASH) at DESY. The room-temperature part of the accelerator is equipped mainly with stripline position monitors. In the accelerating cryo-modules there are cavity and re-entrant cavity BPMs, which will not be discussed here. In the undulator part of the machine button BPMs are used. This area requires a single bunch resolution of 10μm. The electronics is based on the AM/PM normalization principle and is externally triggered. Single-bunch position is measured. This paper presents the methods used to determine the resolution of the BPMs. The results based on correlations between different BPMs along the machine are compared to noise measurements in the RF lab. The performance and difficulties with the BPM design and the current electronics as well as its development are discussed.

  9. The influence of lateral beam profile modifications in scanned proton and carbon ion therapy: a Monte Carlo study

    CERN Document Server

    Parodi, K; Kraemer, M; Sommerer, F; Naumann, J; Mairani, A; Brons, S

    2010-01-01

    Scanned ion beam delivery promises superior flexibility and accuracy for highly conformal tumour therapy in comparison to the usage of passive beam shaping systems. The attainable precision demands correct overlapping of the pencil-like beams which build up the entire dose distribution in the treatment field. In particular, improper dose application due to deviations of the lateral beam profiles from the nominal planning conditions must be prevented via appropriate beam monitoring in the beamline, prior to the entrance in the patient. To assess the necessary tolerance thresholds of the beam monitoring system at the Heidelberg Ion Beam Therapy Center, Germany, this study has investigated several worst-case scenarios for a sensitive treatment plan, namely scanned proton and carbon ion delivery to a small target volume at a shallow depth. Deviations from the nominal lateral beam profiles were simulated, which may occur because of misaligned elements or changes of the beam optic in the beamline. Data have been an...

  10. Investigation of the depth profile of ion beam induced nanopatterns on Si with simultaneous metal incorporation

    Energy Technology Data Exchange (ETDEWEB)

    Khanbabaee, Behnam; Arezki, Bahia; Biermanns, Andreas; Pietsch, Ullrich [Festkoerperphysik, Universitaet Siegen, Siegen (Germany); Cornejo, Marina; Frost, Frank [Leibniz-Institut fuer Oberflaechenmodifizierung (IOM), Leipzig (Germany)

    2011-07-01

    Ion beam sputtering of semiconductor surfaces can modify the surface and produce a diversity of surface topographies such as periodic ripples or dot structures depended on sputtering parameters. Well ordered nanostructured surfaces have widely technological applications. Recent experiments have shown that the incorporation of metallic impurity atoms during the sputtering process plays a crucial role in pattern formation on the surfaces. These findings offer a new degree of freedom to control pattern formation. In this contribution we report on surface patterning due to Kr ion beam erosion on silicon surfaces with simultaneous Fe and Cr incorporation. We used X-ray reflectivity (XRR) to determine the depth profiles of metal ions as function of ion beam divergence angles and the mean incidence angle of the ions with respect to the surface normal. Depth profiles are correlated with degree of pattern formation determined by AFM. We show that the mean penetration depth and concentration of metal ions depends on the divergence angle of Kr beam provided by Kaufman source which supports the assumption that metal ions are created due to parasitic interaction of the Kr beam with the steel plate lining. The evaluated depth profile by XRR is in good agreement with SIMS and RBS results.

  11. Axisymmetric instability of a self-pinched beam with rounded radial density profile

    International Nuclear Information System (INIS)

    Chen, H.C.; Uhm, H.S.

    1983-01-01

    The axisymmetric perturbations (sausage and hollowing modes) of an intense relativistic self-pinched electron beam propagating in a resistive plasma background are studied, especially for a beam with rounded radial density profile. The Bennett profiles are assumed for both the equilibrium beam current J/sub b/(r) = J/sub b/(0) (1+r 2 /R 2 /sub b/) -2 and plasma return current J/sub p/(r) = -fJ/sub b/(0) (1+r 2 /R 2 /sub p/) -2 , where R/sub b/ and R/sub p/ are the characteristic radii of the beam and plasma return currents, respectively. It is further assumed that the electric conductivity sigma(r) of the plasma channel is proportional to the return current. For a paraxial electron beam with complete space-charge neutralization by the ambient plasma, the axisymmetric modes can be destabilized by the phase lag between the magnetic field and beam current, even without the plasma return current. The plasma return current significantly modifies the growth rate of the instability such that the ratio of plasma current to beam current (-I/sub p//I/sub b/ = fR 2 /sub p// iR 2 /sub b/) largely determines the stability character of the beam. Furthermore, for the same fractional current neutralization f, the modes are highly unstable for a smaller ratio of plasma to beam radius R/sub p//R/sub b/. As compared to the resistive hose instability, the growth rates for the hollowing mode can be larger than those of the hose mode, while the sausage mode is much stabler than the hose mode. Stability properties are illustrated in detail for various system parameters

  12. Application of high-resolution domestic electricity load profiles in network modelling

    DEFF Research Database (Denmark)

    Marszal, Anna Joanna; Mendaza, Iker Diaz de Cerio; Heiselberg, Per Kvols

    2016-01-01

    the generated profiles are inputted in a low-voltage network model created in DIgSILENT PowerFactory. By means of employing 1 hour based demand and generation profiles in during dynamic studies, the representation of the local power system performance might sometimes not be as accurate as needed. In the test...... with modeling when 1-minute domestic electricity demand and generation profiles are used as inputs. The analysis is done with a case study of low-voltage network located in Northern Denmark. The analysis includes two parts. The first part focuses on modeling the domestic demands and on-site generation in 1......-minute resolution. The load profiles of the household appliances are created using a bottom-up model, which uses the 1-minute cycle power use characteristics of a single appliance as the main building block. The profiles of heavy electric appliances, such as heat pump, are not included in the above...

  13. Application of PLC technology in measurement of beam profile on 100 MeV accelerator

    International Nuclear Information System (INIS)

    Yu Luyang; Chinese Academy of Sciences, Beijing; Chen Yongzhong; Chen Yongzhong; Liu Dekang; Chinese Academy of Sciences, Beijing

    2005-01-01

    A comprehensive introduction is given to the real-time measuring method, which is based on the Programmable Logic Controller (PLC) technology and can measure intensity and profile of the beam by a scintillator screen. The whole system has many advantages, such as good reliability, high precision, intuitional measurement, etc. due to the use of the PLC and Labview software. (authors)

  14. Fabrication of Faraday Cup Array for the Measurement of 2-Dimensional Proton Beam Profile

    International Nuclear Information System (INIS)

    Jung, Myunghwan; Kim, Bom Sok; Kim, Kyeryung

    2014-01-01

    It has an advantage of easy-to-use and possible to visually check, immediately; on the other hand, the measurement range is very limited. Another method is using the CCD camera-scintillator device such as p43 phosphor screen or chromox. A variety of faraday cup detectors have been recently introduced. The faraday cup is one of the powerful and popular tools for the measurement of beam current. By using several faraday cups in array geometry, it is possible to observe current distribution. In this study, we developed an external faraday cup array for the measure the beam current and profile at a KOMAC (Korea Multi-purpose Accelerator Complex) beam utilization facility. To measure the beam profile, before fabrication of faraday cup array, we use gafchromic film. By making the faraday cup array we were able to reduce the consumption of Gafchromic film and a more accurate diagnosis of the proton beam is possible. The use of faraday cup array, experiment using the proton beam is more reliable and confident

  15. Measurement of dynamic wedge angles and beam profiles by means of MRI ferrous sulphate gel dosimetry

    Science.gov (United States)

    Bengtsson, Magnus; Furre, Torbjørn; Rødal, Jan; Skretting, Arne; Olsen, Dag R.

    1996-02-01

    The purpose of this study is to examine the possible value of measuring the dose distribution in dynamic wedge photon beams using ferrous sulphate gel phantoms analysed by MRI. The wedge angles and dose profiles were measured for a field size of and for dynamic wedge angles of , , and using a 15 MV photon beam generated from a Clinac 2100 CD (Varian). The dose profiles obtained from MRI ferrous sulphate gel were in good agreement with the dose measurements performed with a diode detector array. Also, the wedge angles determined from the MRI ferrous sulphate gel agreed well with the values obtained by using film dosimetry and with calculations by use of TMS (treatment planning system) (Helax, Uppsala, Sweden). The study demonstrated that MRI ferrous sulphate gel dosimetry is an adequate tool for measurements of some beam characteristics of dynamic radiation fields.

  16. Design and development of high-resolution atomic beam fluorescence spectroscopy facility for isotope shift and hyperfine structure measurements

    International Nuclear Information System (INIS)

    Acharyulu, G.V.S.G.; Sankari, M.; Kiran Kumar, P.V.; Suryanarayana, M.V.

    2012-01-01

    A high-resolution atomic beam fluorescence spectroscopy facility for the determination of isotope shifts and hyperfine structure in atomic species has been designed and developed. A resistively heated graphite tube atomic beam source was designed, tested and integrated into a compact interaction chamber for atomic beam fluorescence experiments. The design of the laser-atom interaction chamber and the source has been modified in a phased manner so as to achieve sub-Doppler resolution. The system has been used to record the hyperfine spectrum of the D2 transitions of Rb and K isotopes. The spectral resolution achieved is ∼ 26 MHz and is adequate to carry out high resolution measurement of isotope shifts and hyperfine structure of various atomic species. The other major advantage of the source is that it requires very small amounts of sample for achieving very good signal to noise ratio. (author)

  17. Electron beam fabrication and characterization of high-resolution magnetic force microscopy tips

    Science.gov (United States)

    Rührig, M.; Porthun, S.; Lodder, J. C.; McVitie, S.; Heyderman, L. J.; Johnston, A. B.; Chapman, J. N.

    1996-03-01

    The stray field, magnetic microstructure, and switching behavior of high-resolution electron beam fabricated thin film tips for magnetic force microscopy (MFM) are investigated with different imaging modes in a transmission electron microscope (TEM). As the tiny smooth carbon needles covered with a thermally evaporated magnetic thin film are transparent to the electron energies used in these TEMs it is possible to observe both the external stray field emanating from the tips as well as their internal domain structure. The experiments confirm the basic features of electron beam fabricated thin film tips concluded from various MFM observations using these tips. Only a weak but highly concentrated stray field is observed emanating from the immediate apex region of the tip, consistent with their capability for high resolution. It also supports the negligible perturbation of the magnetization sample due to the tip stray field observed in MFM experiments. Investigation of the magnetization distributions within the tips, as well as preliminary magnetizing experiments, confirm a preferred single domain state of the high aspect ratio tips. To exclude artefacts of the observation techniques both nonmagnetic tips and those supporting different magnetization states are used for comparison.

  18. Scintillation screen materials for beam profile measurements of high energy ion beams

    Energy Technology Data Exchange (ETDEWEB)

    Krishnakumar, Renuka

    2016-06-22

    For the application as a transverse ion beam diagnostics device, various scintillation screen materials were analysed. The properties of the materials such as light output, image reproduction and radiation stability were investigated with the ion beams extracted from heavy ion synchrotron SIS-18. The ion species (C, Ne, Ar, Ta and U) were chosen to cover the large range of elements in the periodic table. The ions were accelerated to the kinetic energies of 200 MeV/u and 300 MeV/u extracted with 300 ms pulse duration and applied to the screens. The particle intensity of the ion beam was varied from 10{sup 4} to 10{sup 9} particles per pulse. The screens were irradiated with typically 40 beam pulses and the scintillation light was captured using a CCD camera followed by characterization of the beam spot. The radiation hardness of the screens was estimated with high intensity Uranium ion irradiation. In the study, a linear light output for 5 orders of magnitude of particle intensities was observed from sensitive scintillators and ceramic screens such as Al{sub 2}O{sub 3}:Cr and Al{sub 2}O{sub 3}. The highest light output was recorded by CsI:Tl and the lowest one by Herasil. At higher beam intensity saturation of light output was noticed from Y and Mg doped ZrO{sub 2} screens. The light output from the screen depends not only on the particle intensity but also on the ion species used for irradiation. The light yield (i.e. the light intensity normalised to the energy deposition in the material by the ion) is calculated from the experimental data for each ion beam setting. It is shown that the light yield for light ions is about a factor 2 larger than the one of heavy ions. The image widths recorded exhibit a dependence on the screens material and differences up to 50 % were registered. On radiation stability analysis with high particle intensity of Uranium ions of about 6 x 10{sup 8} ppp, a stable performance in light output and image reproduction was documented from Al

  19. Determination of boundaries between ranges of high and low gradient of beam profile.

    Science.gov (United States)

    Wendykier, Jacek; Bieniasiewicz, Marcin; Grządziel, Aleksandra; Jedynak, Tadeusz; Kośniewski, Wiktor; Reudelsdorf, Marta; Wendykier, Piotr

    2016-01-01

    This work addresses the problem of treatment planning system commissioning by introducing a new method of determination of boundaries between high and low gradient in beam profile. The commissioning of a treatment planning system is a very important task in the radiation therapy. One of the main goals of this task is to compare two field profiles: measured and calculated. Applying points of 80% and 120% of nominal field size can lead to the incorrect determination of boundaries, especially for small field sizes. The method that is based on the beam profile gradient allows for proper assignment of boundaries between high and low gradient regions even for small fields. TRS 430 recommendations for commissioning were used. The described method allows a separation between high and low gradient, because it directly uses the value of the gradient of a profile. For small fields, the boundaries determined by the new method allow a commissioning of a treatment planning system according to the TRS 430, while the point of 80% of nominal field size is already in the high gradient region. The method of determining the boundaries by using the beam profile gradient can be extremely helpful during the commissioning of the treatment planning system for Intensity Modulated Radiation Therapy or for other techniques which require very small field sizes.

  20. Technique using axicons for generating flat-top laser-beam profiles

    International Nuclear Information System (INIS)

    Viswanathan, V.K.; Woodfin, G.L.; Stahl, D.; Carpenter, J.P.; Kyrala, G.

    1983-01-01

    In certain fusion experiments using CO 2 lasers, like Helios, it is desired to produce a focal spot several times larger than the nominal focal spot, with a flat beam profile. The typical focal spot in Helios is roughly 70 μm and just defocussing the beam produces beam breakup, with several hot spots with roughly the original diameter, and a gaussian distribution. A number of schemes were tried to achieve a large spot with desired characteristics. These are described in the article. Axicons were found to produce spots with desired characteristics. Axicons are lenses or mirrors having a cone-shaped surface. The various schemes are described, as well as an experiment in Helios which confirmed that axicons produced the spots with desirable characteristics. Helios is an 8-beam CO 2 laser which produces 10 kJ at power in excess of 20 TW. It is currently being used for Laser Fusion studies at the Los Alamos National Laboratory

  1. Commissioning and First Results of the Electron Beam Profiler in the Main Injector at Fermilab

    Energy Technology Data Exchange (ETDEWEB)

    Thurman-Keup, R. [Fermilab; Alvarez, M. [Fermilab; Fitzgerald, J. [Fermilab; Lundberg, C. [Fermilab; Prieto, P. [Fermilab; Zagel, J. [Fermilab; Blokland, W. [Oak Ridge

    2017-08-01

    The planned neutrino program at Fermilab requires large proton beam intensities in excess of 2 MW. Measuring the transverse profiles of these high intensity beams is challenging and often depends on non-invasive techniques. One such technique involves measuring the deflection of a probe beam of electrons with a trajectory perpendicular to the proton beam. A device such as this is already in use at the Spallation Neutron Source at ORNL and a similar device has been installed in the Main Injector at Fermilab. Commissioning of the device is in progress with the goal of having it operational by the end of the year. The status of the commissioning and initial results will be presented

  2. High resolution measurements and modeling of auroral hydrogen emission line profiles

    Directory of Open Access Journals (Sweden)

    B. S. Lanchester

    Full Text Available Measurements in the visible wavelength range at high spectral resolution (1.3 Å have been made at Longyearbyen, Svalbard (15.8 E,78.2 N during an interval of intense proton precipitation. The shape and Doppler shift of hydrogen Balmer beta line profiles have been compared with model line profiles, using as input ion energy spectra from almost coincident passes of the FAST and DMSP spacecraft. The comparison shows that the simulation contains the important physical processes that produce the profiles, and confirms that measured changes in the shape and peak wave-length of the hydrogen profiles are the result of changing energy input. This combination of high resolution measurements with modeling provides a method of estimating the incoming energy and changes in flux of precipitating protons over Svalbard, for given energy and pitch-angle distributions. Whereas for electron precipitation, information on the incident particles is derived from brightness and brightness ratios which require at least two spectral windows, for proton precipitation the Doppler profile of resulting hydrogen emission is directly related to the energy and energy flux of the incident energetic protons and can be used to gather information about the source region. As well as the expected Doppler shift to shorter wavelengths, the measured profiles have a significant red-shifted component, the result of upward flowing emitting hydrogen atoms.

    Key words. Ionosphere (auroral ionosphere; particle precipitation – Magnetospheric physics (auroral phenomena

  3. High resolution measurements and modeling of auroral hydrogen emission line profiles

    Directory of Open Access Journals (Sweden)

    B. S. Lanchester

    2003-07-01

    Full Text Available Measurements in the visible wavelength range at high spectral resolution (1.3 Å have been made at Longyearbyen, Svalbard (15.8 E,78.2 N during an interval of intense proton precipitation. The shape and Doppler shift of hydrogen Balmer beta line profiles have been compared with model line profiles, using as input ion energy spectra from almost coincident passes of the FAST and DMSP spacecraft. The comparison shows that the simulation contains the important physical processes that produce the profiles, and confirms that measured changes in the shape and peak wave-length of the hydrogen profiles are the result of changing energy input. This combination of high resolution measurements with modeling provides a method of estimating the incoming energy and changes in flux of precipitating protons over Svalbard, for given energy and pitch-angle distributions. Whereas for electron precipitation, information on the incident particles is derived from brightness and brightness ratios which require at least two spectral windows, for proton precipitation the Doppler profile of resulting hydrogen emission is directly related to the energy and energy flux of the incident energetic protons and can be used to gather information about the source region. As well as the expected Doppler shift to shorter wavelengths, the measured profiles have a significant red-shifted component, the result of upward flowing emitting hydrogen atoms.Key words. Ionosphere (auroral ionosphere; particle precipitation – Magnetospheric physics (auroral phenomena

  4. First-Year Wilkinson Microwave Anisotropy Probe (WMAP) Observations: Beam Profiles and Window Functions

    Science.gov (United States)

    Page, L.; Barnes, C.; Hinshaw, G.; Spergel, D. N.; Weiland, J. L.; Wollack, E.; Bennett, C. L.; Halpern, M.; Jarosik, N.; Kogut, A.; Limon, M.; Meyer, S. S.; Tucker, G. S.; Wright, E. L.

    2003-09-01

    Knowledge of the beam profiles is of critical importance for interpreting data from cosmic microwave background experiments. In this paper, we present the characterization of the in-flight optical response of the WMAP satellite. The main-beam intensities have been mapped to the satellite in the same observing mode as for CMB observations. The beam patterns closely follow the prelaunch expectations. The full width at half-maximum is a function of frequency and ranges from 0.82d at 23 GHz to 0.21d at 94 GHz; however, the beams are not Gaussian. We present (a) the beam patterns for all 10 differential radiometers, showing that the patterns are substantially independent of polarization in all but the 23 GHz channel; (b) the effective symmetrized beam patterns that result from WMAP's compound spin observing pattern; (c) the effective window functions for all radiometers and the formalism for propagating the window function uncertainty; and (d) the conversion factor from point-source flux to antenna temperature. A summary of the systematic uncertainties, which currently dominate our knowledge of the beams, is also presented. The constancy of Jupiter's temperature within a frequency band is an essential check of the optical system. The tests enable us to report a calibration of Jupiter to 1%-3% accuracy relative to the CMB dipole. WMAP is the result of a partnership between Princeton University and the NASA Goddard Space Flight Center. Scientific guidance is provided by the WMAP Science Team.

  5. Nutrient Profiles and Volatile Odorous Compounds of Raw Milk After Exposure to Electron Beam Pasteurizing Doses.

    Science.gov (United States)

    Ward, Lindsay R; Kerth, Chris R; Pillai, Suresh D

    2017-07-01

    Raw milk is known to contain relatively high numbers of microorganisms, some of which include microbial pathogens. Electron beam (eBeam) processing is a nonthermal pasteurization food processing technology. The underlying hypothesis was that eBeam processing will not negatively influence the composition, nutrient content, and aroma profile of raw milk. Raw milk samples were exposed to eBeam doses of 1 and 2 kGy, since our studies had shown that 2 kGy is suitable for raw milk pasteurization. The untreated and eBeam-treated raw milk samples were analyzed to detect changes in lactose, vitamin B 2 , vitamin B 12 , and calcium concentrations. The possible breakdown of casein and whey proteins and lipid oxidation were investigated along with the formation of volatile aroma compounds. Even though vitamin B 2 showed a 31.6% decrease in concentration, the B 2 content in eBeam-pasteurized raw milk met all USDA nutritional guidelines. Even though there were no indications of lipid oxidation after the 2.0-kGy eBeam treatment, there was lipid oxidation (58%) after 7 d of refrigerated storage. However, based on the GC-olfactory analysis, the lipid oxidation did not necessarily result in the development of a wide variety of off-odors. © 2017 Institute of Food Technologists®.

  6. Quantitative low-energy ion beam characterization by beam profiling and imaging via scintillation screens.

    Czech Academy of Sciences Publication Activity Database

    Germer, S.; Pietag, F.; Polák, Jaroslav; Arnold, T.

    2016-01-01

    Roč. 87, č. 11 (2016), č. článku 113301. ISSN 0034-6748. [Topical Conference on High-Temperature Plasma Diagnostics/21./. Madison, 05.06.2016-09.06.2016] Institutional support: RVO:61389021 Keywords : Current density * Etching * Faraday cups * Ion beam source s * Cameras Subject RIV: BL - Plasma and Gas Discharge Physics OBOR OECD: 2.11 Other engineering and technologies Impact factor: 1.515, year: 2016 http://aip.scitation.org/doi/full/10.1063/1.4964701

  7. Crack Identification in CFRP Laminated Beams Using Multi-Resolution Modal Teager–Kaiser Energy under Noisy Environments

    Science.gov (United States)

    Xu, Wei; Cao, Maosen; Ding, Keqin; Radzieński, Maciej; Ostachowicz, Wiesław

    2017-01-01

    Carbon fiber reinforced polymer laminates are increasingly used in the aerospace and civil engineering fields. Identifying cracks in carbon fiber reinforced polymer laminated beam components is of considerable significance for ensuring the integrity and safety of the whole structures. With the development of high-resolution measurement technologies, mode-shape-based crack identification in such laminated beam components has become an active research focus. Despite its sensitivity to cracks, however, this method is susceptible to noise. To address this deficiency, this study proposes a new concept of multi-resolution modal Teager–Kaiser energy, which is the Teager–Kaiser energy of a mode shape represented in multi-resolution, for identifying cracks in carbon fiber reinforced polymer laminated beams. The efficacy of this concept is analytically demonstrated by identifying cracks in Timoshenko beams with general boundary conditions; and its applicability is validated by diagnosing cracks in a carbon fiber reinforced polymer laminated beam, whose mode shapes are precisely acquired via non-contact measurement using a scanning laser vibrometer. The analytical and experimental results show that multi-resolution modal Teager–Kaiser energy is capable of designating the presence and location of cracks in these beams under noisy environments. This proposed method holds promise for developing crack identification systems for carbon fiber reinforced polymer laminates. PMID:28773016

  8. Profiling of integral membrane proteins and their post translational modifications using high-resolution mass spectrometry

    Science.gov (United States)

    Souda, Puneet; Ryan, Christopher M.; Cramer, William A.; Whitelegge, Julian

    2011-01-01

    Integral membrane proteins pose challenges to traditional proteomics approaches due to unique physicochemical properties including hydrophobic transmembrane domains that limit solubility in aqueous solvents. A well resolved intact protein molecular mass profile defines a protein’s native covalent state including post-translational modifications, and is thus a vital measurement toward full structure determination. Both soluble loop regions and transmembrane regions potentially contain post-translational modifications that must be characterized if the covalent primary structure of a membrane protein is to be defined. This goal has been achieved using electrospray-ionization mass spectrometry (ESI-MS) with low-resolution mass analyzers for intact protein profiling, and high-resolution instruments for top-down experiments, toward complete covalent primary structure information. In top-down, the intact protein profile is supplemented by gas-phase fragmentation of the intact protein, including its transmembrane regions, using collisionally activated and/or electroncapture dissociation (CAD/ECD) to yield sequence-dependent high-resolution MS information. Dedicated liquid chromatography systems with aqueous/organic solvent mixtures were developed allowing us to demonstrate that polytopic integral membrane proteins are amenable to ESI-MS analysis, including top-down measurements. Covalent post-translational modifications are localized regardless of their position in transmembrane domains. Top-down measurements provide a more detail oriented high-resolution description of post-transcriptional and post-translational diversity for enhanced understanding beyond genomic translation. PMID:21982782

  9. The generation of absorbed dose profiles of proton beam in water using Geant4 code

    International Nuclear Information System (INIS)

    Christovao, Marilia T.; Campos, Tarcisio Passos R. de

    2007-01-01

    The present article approaches simulations on the proton beam radiation therapy, using an application based on the code GEANT4, with Open GL as a visualization drive and JAS3 (Java Analysis Studio) analysis data tools systems, implementing the AIDA interfaces. The proton radiotherapy is adapted to treat cancer or other benign tumors that are close to sensitive structures, since it allows precise irradiation of the target with high doses, while the health tissues adjacent to vital organs and tissues are preserved, due to physical property of dose profile. GEANT4 is a toolkit for simulating the transport of particles through matter, in complex geometries. Taking advantage of the object-oriented project features, the user can adapt or extend the tool in all domain, due to the flexibility of the code, providing a subroutine's group for materials definition, geometries and particles properties in agreement with the user's needs to generate the Monte Carlo simulation. In this paper, the parameters of beam line used in the simulation possess adjustment elements, such as: the range shifter, composition and dimension; the beam line, energy, intensity, length, according with physic processes applied. The simulation result is the depth dose profiles on water, dependent on the various incident beam energy. Starting from those profiles, one can define appropriate conditions for proton radiotherapy in ocular region. (author)

  10. Beam Profile Disturbances from Implantable Pacemakers or Implantable Cardioverter-Defibrillator Interactions

    Energy Technology Data Exchange (ETDEWEB)

    Gossman, Michael S., E-mail: mgossman@tsrcc.com [Tri-State Regional Cancer Center, Medical Physics Section, Ashland, KY (United States); Comprehensive Heart and Vascular Associates, Heart and Vascular Center, Ashland, KY (United States); Medtronic, Inc., External Research Program, Mounds View, MN (United States); Nagra, Bipinpreet; Graves-Calhoun, Alison; Wilkinson, Jeffrey [Tri-State Regional Cancer Center, Medical Physics Section, Ashland, KY (United States); Comprehensive Heart and Vascular Associates, Heart and Vascular Center, Ashland, KY (United States); Medtronic, Inc., External Research Program, Mounds View, MN (United States)

    2011-01-01

    The medical community is advocating for progressive improvement in the design of implantable cardioverter-defibrillators and implantable pacemakers to accommodate elevations in dose limitation criteria. With advancement already made for magnetic resonance imaging compatibility in some, a greater need is present to inform the radiation oncologist and medical physicist regarding treatment planning beam profile changes when such devices are in the field of a therapeutic radiation beam. Treatment plan modeling was conducted to simulate effects induced by Medtronic, Inc.-manufactured devices on therapeutic radiation beams. As a continuation of grant-supported research, we show that radial and transverse open beam profiles of a medical accelerator were altered when compared with profiles resulting when implantable pacemakers and cardioverter-defibrillators are placed directly in the beam. Results are markedly different between the 2 devices in the axial plane and the sagittal planes. Vast differences are also presented for the therapeutic beams at 6-MV and 18-MV x-ray energies. Maximum changes in percentage depth dose are observed for the implantable cardioverter-defibrillator as 9.3% at 6 MV and 10.1% at 18 MV, with worst distance to agreement of isodose lines at 2.3 cm and 1.3 cm, respectively. For the implantable pacemaker, the maximum changes in percentage depth dose were observed as 10.7% at 6 MV and 6.9% at 18 MV, with worst distance to agreement of isodose lines at 2.5 cm and 1.9 cm, respectively. No differences were discernible for the defibrillation leads and the pacing lead.

  11. Modification of NUR II neutron beam profile of MINT TRIGA MARK II research reactor for digital neutron radiography

    International Nuclear Information System (INIS)

    Muhammad Rawi Mohamed Zin; Azali Muhammad; Abdul Aziz Mohamed; Rafhayudi Jamro; Syed Nasaruddin Syed Idris; Ng Aik Hao; Rosly Jaafar

    2006-01-01

    A cone neutron beam collimated by a 5.4 cm aperture produced in the Neutron Radiography II (NUR II) via a step divergence collimator had to be modified to fulfill 5 cm x 6 cm dimension of the scintillation screen placed in the charge couple device (ccd) camera. The required convergence neutron beam was obtained by a simple collimator-beam plug plugged in front of the NUR II beam port. The calculations involved in designing the collimator-beam plug had to take into account not only the neutron beam profiling but also the neutron and gamma shielding and are discussed in this article. (Author)

  12. SU-F-T-478: Effect of Deconvolution in Analysis of Mega Voltage Photon Beam Profiles

    Energy Technology Data Exchange (ETDEWEB)

    Muthukumaran, M [Apollo Speciality Hospitals, Chennai, Tamil Nadu (India); Manigandan, D [Fortis Cancer Institute, Mohali, Punjab (India); Murali, V; Chitra, S; Ganapathy, K [Apollo Speciality Hospital, Chennai, Tamil Nadu (India); Vikraman, S [JAYPEE HOSPITAL- RADIATION ONCOLOGY, Noida, UTTAR PRADESH (India)

    2016-06-15

    Purpose: To study and compare the penumbra of 6 MV and 15 MV photon beam profiles after deconvoluting different volume ionization chambers. Methods: 0.125cc Semi-Flex chamber, Markus Chamber and PTW Farmer chamber were used to measure the in-plane and cross-plane profiles at 5 cm depth for 6 MV and 15 MV photons. The profiles were measured for various field sizes starting from 2×2 cm till 30×30 cm. PTW TBA scan software was used for the measurements and the “deconvolution” functionality in the software was used to remove the volume averaging effect due to finite volume of the chamber along lateral and longitudinal directions for all the ionization chambers. The predicted true profile was compared and the change in penumbra before and after deconvolution was studied. Results: After deconvoluting the penumbra decreased by 1 mm for field sizes ranging from 2 × 2 cm till 20 x20 cm. This is observed for along both lateral and longitudinal directions. However for field sizes from 20 × 20 till 30 ×30 cm the difference in penumbra was around 1.2 till 1.8 mm. This was observed for both 6 MV and 15 MV photon beams. The penumbra was always lesser in the deconvoluted profiles for all the ionization chambers involved in the study. The variation in difference in penumbral values were in the order of 0.1 till 0.3 mm between the deconvoluted profile along lateral and longitudinal directions for all the chambers under study. Deconvolution of the profiles along longitudinal direction for Farmer chamber was not good and is not comparable with other deconvoluted profiles. Conclusion: The results of the deconvoluted profiles for 0.125cc and Markus chamber was comparable and the deconvolution functionality can be used to overcome the volume averaging effect.

  13. Propagation profile of ablation front driven by a nonuniform UV laser beam

    International Nuclear Information System (INIS)

    Matsushima, I.; Tanimoto, M.; Kasai, T.; Yano, M.

    1985-01-01

    Spatial profile of ablation front is observed under the irradiation of spatially modulated 0.27-μm laser beam. Propagation depth of the ablation front is derived by means of various methods which detect x-ray radiation from aluminum substrates overcoated with polyethylene layers of different thicknesses. A higher mass ablation rate is observed for the UV laser than the longer wavelength lasers. However, observation with an x-ray television camera shows that the spatial nonuniformity in the laser beam is projected on the ablation front surface without substantial smoothing

  14. Manipulation of laser-accelerated proton beam profiles by nanostructured and microstructured targets

    Directory of Open Access Journals (Sweden)

    L. Giuffrida

    2017-08-01

    Full Text Available Nanostructured and microstructured thin foils have been fabricated and used experimentally as targets to manipulate the spatial profile of proton bunches accelerated through the interaction with high intensity laser pulses (6×10^{19}  W/cm^{2}. Monolayers of polystyrene nanospheres were placed on the rear surfaces of thin plastic targets to improve the spatial homogeneity of the accelerated proton beams. Moreover, thin targets with grating structures of various configurations on their rear sides were used to modify the proton beam divergence. Experimental results are presented, discussed, and supported by 3D particle-in-cell numerical simulations.

  15. Gene-expression profiling after exposure to C-ion beams

    International Nuclear Information System (INIS)

    Saegusa, Kumiko; Furuno, Aki; Ishikawa, Kenichi; Ishikawa, Atsuko; Ohtsuka, Yoshimi; Kawai, Seiko; Imai, Takashi; Nojima, Kumie

    2005-01-01

    It is recognized that carbon-ion beam kills cancer cells more efficiently than X-ray. In this study we have compared cellular gene expression response after carbon-ion beam exposure with that after X-ray exposure. Gene expression profiles of cultured neonatal human dermal fibroblasts (NHDF) at 0, 1, 3, 6, 12, 18, and 24 hr after exposure to 0.1, 2 and 5 Gy of X-ray or carbon-ion beam were obtained using 22K oligonucleotide microarray. N-way ANOVA analysis of whole gene expression data sets selected 960 genes for carbon-ion beam and 977 genes for X-ray, respectively. Interestingly, majority of these genes (91% for carbon-ion beam and 88% for X-ray, respectively) were down regulated. The selected genes were further classified by their dose-dependence or time-dependence of gene expression change (fold change>1.5). It was revealed that genes involved in cell proliferation had tendency to show time-dependent up regulation by carbon-ion beam. Another N-way ANOVA analysis was performed to select 510 genes, and further selection was made to find 70 genes that showed radiation species-dependent gene expression change (fold change>1.25). These genes were then categorized by the K-Mean clustering method into 4 clusters. Each cluster showed tendency to contain genes involved in cell cycle regulation, cell death, responses to stress and metabolisms, respectively. (author)

  16. Resolution Improvement and Pattern Generator Development for the Maskless Micro-Ion-Beam Reduction Lithography System

    International Nuclear Information System (INIS)

    Jiang, Ximan

    2006-01-01

    The shrinking of IC devices has followed the Moore's Law for over three decades, which states that the density of transistors on integrated circuits will double about every two years. This great achievement is obtained via continuous advance in lithography technology. With the adoption of complicated resolution enhancement technologies, such as the phase shifting mask (PSM), the optical proximity correction (OPC), optical lithography with wavelength of 193 nm has enabled 45 nm printing by immersion method. However, this achievement comes together with the skyrocketing cost of masks, which makes the production of low volume application-specific IC (ASIC) impractical. In order to provide an economical lithography approach for low to medium volume advanced IC fabrication, a maskless ion beam lithography method, called Maskless Micro-ion-beam Reduction Lithography (MMRL), has been developed in the Lawrence Berkeley National Laboratory. The development of the prototype MMRL system has been described by Dr. Vinh Van Ngo in his Ph.D. thesis. But the resolution realized on the prototype MMRL system was far from the design expectation. In order to improve the resolution of the MMRL system, the ion optical system has been investigated. By integrating a field-free limiting aperture into the optical column, reducing the electromagnetic interference and cleaning the RF plasma, the resolution has been improved to around 50 nm. Computational analysis indicates that the MMRL system can be operated with an exposure field size of 0.25 mm and a beam half angle of 1.0 mrad on the wafer plane. Ion-ion interactions have been studied with a two-particle physics model. The results are in excellent agreement with those published by the other research groups. The charge-interaction analysis of MMRL shows that the ion-ion interactions must be reduced in order to obtain a throughput higher than 10 wafers per hour on 300-mm wafers. In addition, two different maskless lithography strategies

  17. Reaching (sub-)micrometer resolution of photo-immobilized proteins using diffracted light beams

    DEFF Research Database (Denmark)

    Skovsen, Esben; Neves Petersen, Teresa; Petersen, Steffen B.

    2008-01-01

    , with dimensions as small as a few micrometers. The ultimate size of the immobilized spots is dependent on the focal area of the UV beam. The technology involves light induced formation of free, reactive thiol groups in molecules containing aromatic residues nearby disulphide bridges. It is not only limited...... to immobilizing molecules according to conventional patterns like microarrays, as any bitmap motif can virtually be used a template for patterning. We now show that molecules (proteins) can be immobilized on a surface with any arbitrary pattern according to diffraction patterns of light. The pattern of photo......-immobilized proteins reproduces the diffraction pattern of light expected with the optical setup. Immobilising biomolecules according to diffraction patterns of light will allow achievement of smaller patterns with higher resolution. The flexibility of this new technology leads to any patterns of photo...

  18. Development of temperature profile sensor at high temporal and spatial resolution

    International Nuclear Information System (INIS)

    Takiguchi, Hiroki; Furuya, Masahiro; Arai, Takahiro

    2017-01-01

    In order to quantify thermo-physical flow field for the industrial applications such as nuclear and chemical reactors, high temporal and spatial measurements for temperature, pressure, phase velocity, viscosity and so on are required to validate computational fluid dynamics (CFD) and subchannel analyses. The paper proposes a novel temperature profile sensor, which can acquire temperature distribution in water at high temporal (a millisecond) and spatial (millimeter) resolutions. The devised sensor acquires electric conductance between transmitter and receiver wires, which is a function of temperature. The sensor comprise wire mesh structure for multipoint and simultaneous temperature measurement in water, which indicated that three-dimensional temperature distribution can be detected in flexible resolutions. For the demonstration of the principle, temperature profile in water was estimated according to pre-determined temperature calibration line against time-averaged impedance. The 16×16 grid sensor visualized fast and multi-dimensional mixing process of a hot water jet into a cold water pool. (author)

  19. Apparatus for tomography in which signal profiles gathered from divergent radiation can be reconstructed in signal profiles, each corresponding with a beam of parallel rays

    International Nuclear Information System (INIS)

    1976-01-01

    A tomograph which is capable of gathering divergent radiations and reconstruct them in signal profiles or images each corresponding with a beam of parallel rays is discussed which may eliminate the interfering point dispersion function which normally occurs

  20. High resolution laser beam induced current images under trichromatic laser radiation: approximation to the solar irradiation.

    Science.gov (United States)

    Navas, F J; Alcántara, R; Fernández-Lorenzo, C; Martín-Calleja, J

    2010-03-01

    A laser beam induced current (LBIC) map of a photoactive surface is a very useful tool when it is necessary to study the spatial variability of properties such as photoconverter efficiency or factors connected with the recombination of carriers. Obtaining high spatial resolution LBIC maps involves irradiating the photoactive surface with a photonic beam with Gaussian power distribution and with a low dispersion coefficient. Laser emission fulfils these characteristics, but against it is the fact that it is highly monochromatic and therefore has a spectral distribution different to solar emissions. This work presents an instrumental system and procedure to obtain high spatial resolution LBIC maps in conditions approximating solar irradiation. The methodology developed consists of a trichromatic irradiation system based on three sources of laser excitation with emission in the red, green, and blue zones of the electromagnetic spectrum. The relative irradiation powers are determined by either solar spectrum distribution or Planck's emission formula which provides information approximate to the behavior of the system if it were under solar irradiation. In turn, an algorithm and a procedure have been developed to be able to form images based on the scans performed by the three lasers, providing information about the photoconverter efficiency of photovoltaic devices under the irradiation conditions used. This system has been checked with three photosensitive devices based on three different technologies: a commercial silicon photodiode, a commercial photoresistor, and a dye-sensitized solar cell. These devices make it possible to check how the superficial quantum efficiency has areas dependent upon the excitation wavelength while it has been possible to measure global incident photon-to-current efficiency values approximating those that would be obtained under irradiation conditions with sunlight.

  1. High-resolution hydrogen profiling in AlGaN/GaN heterostructures grown by different epitaxial methods

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez-Posada Flores, F; Redondo-Cubero, A; Bengoechea, A; Brana, A F; Munoz, E [Instituto de Sistemas Optoelectronicos y Microtecnologia (ISOM) and Dpto. IngenierIa Electronica (DIE), ETSI de Telecomunicacion, Universidad Politecnica de Madrid, E-28040 Madrid (Spain); Gago, R [Centro de Micro-Analisis de Materiales, Universidad Autonoma de Madrid, E-28049 Madrid (Spain); Jimenez, A [Dpto. Electronica, Escuela Politecnica Superior, Universidad de Alcala, E-28805 Alcala de Henares, Madrid (Spain); Grambole, D, E-mail: fposada@die.upm.e [Institute of Ion Beam Physics and Materials Research, Forschungszentrum Dresden-Rossendorf, PF 51019, D-01314 Dresden (Germany)

    2009-03-07

    Hydrogen (H) incorporation into AlGaN/GaN heterostructures used in high electron mobility transistors, grown by different methods, is studied by high-resolution depth profiling. Samples grown on sapphire and Si(1 1 1) substrates by molecular-beam epitaxy and metal-organic vapour phase epitaxy; involving H-free and H-containing precursors, were analysed to evaluate the eventual incorporation of H into the wafer. The amount of H was measured by means of nuclear reaction analysis (NRA) using the {sup 1}H({sup 15}N,{alpha}{gamma}){sup 12}C reaction up to a depth of {approx}110 nm into the heterostructures. Interestingly, the H profiles are similar in all the samples analysed, with an increasing H content towards the surface and a negligible H incorporation into the GaN layer (0.24 {+-} 0.08 at%) or at the AlGaN/GaN interface. Therefore, NRA shows that H uptake is not related to the growth process or technique employed and that H contamination may be due to external sources after growth. The eventual correlation between topographical defects on the AlGaN surface and the H concentration are also discussed.

  2. Position sensitive detection coupled to high-resolution time-of-flight mass spectrometry: Imaging for molecular beam deflection experiments

    International Nuclear Information System (INIS)

    Abd El Rahim, M.; Antoine, R.; Arnaud, L.; Barbaire, M.; Broyer, M.; Clavier, Ch.; Compagnon, I.; Dugourd, Ph.; Maurelli, J.; Rayane, D.

    2004-01-01

    We have developed and tested a high-resolution time-of-flight mass spectrometer coupled to a position sensitive detector for molecular beam deflection experiments. The major achievement of this new spectrometer is to provide a three-dimensional imaging (X and Y positions and time-of-flight) of the ion packet on the detector, with a high acquisition rate and a high resolution on both the mass and the position. The calibration of the experimental setup and its application to molecular beam deflection experiments are discussed

  3. Simulation calculation for the energy deposition profile and the transmission fraction of intense pulsed electron beam at various incident angles

    International Nuclear Information System (INIS)

    Yang Hailiang; Qiu Aici; Zhang Jiasheng; Huang Jianjun; Sun Jianfeng

    2002-01-01

    The incident angles have a heavy effect on the intense pulsed electron beam energy deposition profile, energy deposition fraction and beam current transmission fraction in material. The author presents electron beam energy deposition profile and energy deposition fraction versus electron energy (0.5-2.0 MeV), at various incident angles for three aluminum targets of various thickness via theoretical calculation. The intense pulsed electron beam current transmission fractions versus electron energy (0.4-1.4 MeV) at various incident angles for three thickness of carbon targets were also theoretically calculated. The calculation results indicate that the deposition energy in unit mass of material surface layer increase with the rise of electron beam incident angle, and electron beam with low incident angle (closer to normal incident angle) penetrates deeper into the target material. The electron beams deposit more energy in unit mass of material surface layer at 60 degree-70 degree incident angle

  4. Development of a procedure to model high-resolution wind profiles from smoothed or low-frequency data

    Science.gov (United States)

    Camp, D. W.

    1977-01-01

    The derivation of simulated Jimsphere wind profiles from low-frequency rawinsonde data and a generated set of white noise data are presented. A computer program is developed to model high-resolution wind profiles based on the statistical properties of data from the Kennedy Space Center, Florida. Comparison of the measured Jimsphere data, rawinsonde data, and the simulated profiles shows excellent agreement.

  5. A LVDT conditioner for the beam profile monitors of the AmPS

    International Nuclear Information System (INIS)

    Es, J.T. van; Trigt, J.H. van.

    1991-01-01

    A LVDT (Linear Variable Differential Transformer) is a transducer for localization. Because of its applied materials, its construction and the absence of bearings etc. the instrument is suitable to be applied in locations where radioactive radiation is present. In order to obtain information about the position of the iron core in the transducer, a conditioner is needed. In 1977 by Digel a conditioner has been developed for the beam profile monitors (moving wire) of MEA because the 'market' could not meet the requirements then. Nowadays the 'market' offers i.c.'s which can take over the work of the Eurocard developed then. Digel has investigated them in order to see if they are applicable for the beam profile monitors of AmPS. (author). 5 refs.; 7 figs.; 13 tabs

  6. Ion acceleration in electrostatic collisionless shock: on the optimal density profile for quasi-monoenergetic beams

    Science.gov (United States)

    Boella, E.; Fiúza, F.; Stockem Novo, A.; Fonseca, R.; Silva, L. O.

    2018-03-01

    A numerical study on ion acceleration in electrostatic shock waves is presented, with the aim of determining the best plasma configuration to achieve quasi-monoenergetic ion beams in laser-driven systems. It was recently shown that tailored near-critical density plasmas characterized by a long-scale decreasing rear density profile lead to beams with low energy spread (Fiúza et al 2012 Phys. Rev. Lett. 109 215001). In this work, a detailed parameter scan investigating different plasma scale lengths is carried out. As result, the optimal plasma spatial scale length that allows for minimizing the energy spread while ensuring a significant reflection of ions by the shock is identified. Furthermore, a new configuration where the required profile has been obtained by coupling micro layers of different densities is proposed. Results show that this new engineered approach is a valid alternative, guaranteeing a low energy spread with a higher level of controllability.

  7. Carbon filament beam profile monitor for high energy proton-antiproton storage rings

    International Nuclear Information System (INIS)

    Evans, L.R.; Shafer, R.E.

    1979-01-01

    The measurement of the evolution of the transverse profile of the stored beams in high energy proton storage rings such as the p-anti p colliders at CERN and at FNAL is of considerable importance. In the present note, a simple monitor is discussed which will allow almost non-destructive measurement of the profile of each individual proton and antiproton bunch separately. It is based on the flying wire technique first used at CEA and more recently at the CPS. A fine carbon filament is passed quickly through the beam, acting as a target for secondary particle production. The flux of secondary particles is measured by two scintillator telescopes, one for protons and one for antiprotons, having an angular acceptance between 30 and 100 mrad. Measurements of secondary particle production performed at FNAL in this angular range show that a very respectable flux can be expected

  8. Metasurfaces-based holography and beam shaping: engineering the phase profile of light

    Directory of Open Access Journals (Sweden)

    Scheuer Jacob

    2016-08-01

    Full Text Available The ability to engineer and shape the phase profile of optical beams is in the heart of any optical element. Be it a simple lens or a sophisticated holographic element, the functionality of such components is dictated by their spatial phase response. In contrast to conventional optical components which rely on thickness variation to induce a phase profile, metasurfaces facilitate the realization of arbitrary phase distributions using large arrays with sub-wavelength and ultrathin (tens of nanometers features. Such components can be easily realized using a single lithographic step and is highly suited for patterning a variety of substrates, including nonplanar and soft surfaces. In this article, we review the recent developments, potential, and opportunities of metasurfaces applications. We focus primarily on flat optical devices, holography, and beam-shaping applications as these are the key ingredients needed for the development of a new generation of optical devices which could find widespread applications in photonics.

  9. The application of image acquisition and processing technology in measurement of beam profile on particle accelerator

    International Nuclear Information System (INIS)

    Nie Zhenpeng; Zheng Yong; Shen Zhiqing; Wang Shaoming

    2000-01-01

    An introduction is given to the real-time measuring method which can measure the intensity and profile of the beam by a scintillator screen on HIRFL (Heavy Ion Research Facility of Lanzhou). Hardware structure is described briefly, methods of the software design are mainly presented. The system can make a dynamic analysis on the faculae image and has many advantages, such as good reliability, high precision, intuitional measurement, friendly interface of the application software etc. Finally some results of measurement are given

  10. A high repetition rate transverse beam profile diagnostic for laser-plasma proton sources

    Science.gov (United States)

    Dover, Nicholas; Nishiuchi, Mamiko; Sakaki, Hironao; Kando, Masaki; Nishitani, Keita

    2016-10-01

    The recently upgraded J-KAREN-P laser can provide PW peak power and intensities approaching 1022 Wcm-2 at 0.1 Hz. Scaling of sheath acceleration to such high intensities predicts generation of protons to near 100 MeV, but changes in electron heating mechanisms may affect the emitted proton beam properties, such as divergence and pointing. High repetition rate simultaneous measurement of the transverse proton distribution and energy spectrum are therefore key to understanding and optimising the source. Recently plastic scintillators have been used to measure online proton beam transverse profiles, removing the need for time consuming post-processing. We are therefore developing a scintillator based transverse proton beam profile diagnostic for use in ion acceleration experiments using the J-KAREN-P laser. Differential filtering provides a coarse energy spectrum measurement, and time-gating allows differentiation of protons from other radiation. We will discuss the design and implementation of the diagnostic, as well as proof-of-principle results from initial experiments on the J-KAREN-P system demonstrating the measurement of sheath accelerated proton beams up to 20 MeV.

  11. On the way to high resolution TEM characterization of dual ion beam irradiated ODS steels

    International Nuclear Information System (INIS)

    Hsiung, L.; Tumey, S.; Fluss, M. J.; King, W.; Marian, J.; Kuntz, J.; Dasher, B. El; Serruys, Y.; Willaime, F.; Kimura, A.

    2009-01-01

    Fission and fusion energy application of ODS steels while appearing promising requires that many key science issues be resolved. Among these issues are our incomplete understanding of the effect of irradiation on low-temperature fracture properties, the role of fusion relevant helium and hydrogen transmutation gases on the deformation and fracture of irradiated material at low and high temperatures, radiation-induced solute segregation and phase stability, mechanisms of swelling suppression in ODS steels, and the effects of radiation damage on localized deformation. While planning to focus on all these issues we are particularly interested in the atomic scale mechanism by which helium is mitigated by the nano scale particles. In order to obtain insight we are performing analytical transmission electron microscopy (AEM), high resolution electron microscopy (HRTEM) to investigate micro-structural and micro-compositional changes and property alterations of Fe-Cr ferritic/martensitic and ODS steels driven by temperature and ion-beam irradiation with Fe, H, and He. As a beginning to a collaboration between LLNL and CEA-Saclay, we have carried out an irradiation of four specimens, Fe, Fe14%Cr, and two ODS steels (14% Cr and 16% Cr) using the dual beam facility at CEA-Saclay (JANNuS). An Fe 8+ beam was implanted at 24 MeV and helium was implanted through a degrader wheel with energies between 1.7 MeV and 1.3 MeV. The nominal radiation parameters were 40 to 25 DPA, 10 to 25 appm He/DPA ratio, and specimen temperatures of ∼425 deg. C. Our goal is to compare the evolved microstructure with respect to the accumulation of helium at or near the particle matrix interface. Preparatory to this first study we have made many hi-resolution analyses of the nano-particles in the two ODS steels which serve as a base line for comparison with the TEM post irradiation examination reported here. These base line studies are reported separately at this conference. (author)

  12. High Temporal Resolution Tropospheric Wind Profile Observations at NASA Kennedy Space Center During Hurricane Irma

    Science.gov (United States)

    Decker, Ryan K.; Barbre, Robert E., Jr.; Huddleston, Lisa; Brauer, Thomas; Wilfong, Timothy

    2018-01-01

    The NASA Kennedy Space Center (KSC) operates a 48-MHz Tropospheric/Stratospheric Doppler Radar Wind Profiler (TDRWP) on a continual basis generating wind profiles between 2-19 km in the support of space launch vehicle operations. A benefit of the continual operability of the system is the ability to provide unique observations of severe weather events such as hurricanes. Over the past two Atlantic Hurricane seasons the TDRWP has made high temporal resolution wind profile observations of Hurricane Irma in 2017 and Hurricane Matthew in 2016. Hurricane Irma was responsible for power outages to approximately 2/3 of Florida's population during its movement over the state(Stein,2017). An overview of the TDRWP system configuration, brief summary of Hurricanes Irma and Matthew storm track in proximity to KSC, characteristics of the tropospheric wind observations from the TDRWP during both events, and discussion of the dissemination of TDRWP data during the event will be presented.

  13. Turn-by-Turn Imaging of the Transverse Beam Profile in PEP-II

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, Alan A.; Petree, Mark; /SLAC

    2006-12-18

    During injection or instability, the transverse profile of an individual bunch in a storage ring can change significantly in a few turns. However, most synchrotron-light imaging techniques are not designed for this time scale. We have developed a novel diagnostic that enhances the utility of a fast gated camera by adding, inexpensively, some features of a dual-axis streak camera, in order to watch the turn-by-turn evolution of the transverse profile, in both x and y. The beam's elliptical profile is reshaped using cylindrical lenses to form a tall and narrow ellipse--essentially the projection of the full ellipse onto one transverse axis. We do this projection twice, by splitting the beam into two paths at different heights, and rotating the ellipse by 90{sup o} on one path. A rapidly rotating mirror scans these vertical ''pencils'' of light horizontally across the photocathode of the camera, which is gated for 3 ns on every Nth ring turn. A single readout of the camera captures 100 images, looking like a stroboscopic photograph of a moving object. We have observed the capture of injected charge into a bunch and the rapid change of beam size at the onset of a fast instability.

  14. Analysis of Relative Biological Effectiveness of Proton Beams and Isoeffective Dose Profiles Using Geant4

    Directory of Open Access Journals (Sweden)

    Hosseini M. A.

    2017-06-01

    Full Text Available Background: The assessment of RBE quantity in the treatment of cancer tumors with proton beams in treatment planning systems (TPS is of high significance. Given the significance of the issue and the studies conducted in the literature, this quantity is fixed and is taken as equal to 1.1. Objective: The main objective of this study was to assess RBE quantity of proton beams and their variations in different depths of the tumor. This dependency makes RBE values used in TPS no longer be fixed as they depend on the depth of the tumor and therefore this dependency causes some changes in the physical dose profile. Materials and Methods: The energy spectrum of protons was measured at various depths of the tumor using proton beam simulations and well as the complete simulation of a cell to a pair of DNA bases through Monte Carlo GEANT4. The resulting energy spectrum was used to estimate the number of double-strand breaks generated in cells. Finally, RBE values were calculated in terms of the penetration depth in the tumor. Results and Conclusion: The simulation results show that the RBE value not fixed terms of the depth of the tumor and it differs from the clinical value of 1.1 at the end of the dose profile and this will lead to a non-uniform absorbed dose profile. Therefore, to create a uniform impact dose area, deep-finishing systems need to be designed by taking into account deep RBE values.

  15. New X-ray beam position monitors with submicron resolution utilizing imaging of scattered X-rays at CHESS

    International Nuclear Information System (INIS)

    Revesz, Peter; Temnykh, Alexander B.; Pauling, Alan K.

    2011-01-01

    At CHESS' A, F and G wiggler beam lines three new video beam position monitors (VBPMs) have been commissioned. These new VBPMs utilize X-rays scattered from the graphite filter (A and F line) or from a beryllium window (G-line) as the white wiggler beam passes through them. As the X-rays scatter in all directions from the scattering medium, a slit camera creates an image of the beam's footprint on a fluorescent screen. This image is then viewed by a CCD camera and analyzed using a computer program to calculate the intensity centroid, the beam profile and integrated intensity. These data are delivered to the CHESS signal archiving system for storage and display. The new systems employ digital cameras. These cameras are free of the noise inherent to the analog systems with long video signal connections. As a result, the beam position data delivered by the new systems are more reliable and accurate as shown by beam position traces using different beam position monitors on the same beam line.

  16. New X-ray beam position monitors with submicron resolution utilizing imaging of scattered X-rays at CHESS

    Energy Technology Data Exchange (ETDEWEB)

    Revesz, Peter, E-mail: pr20@cornell.edu [Cornell University, Cornell High Energy Synchrotron Source, Ithaca 14850, NY (United States); Temnykh, Alexander B. [Cornell University, Laboratory for Elem-Particle Physics, Ithaca 14850, NY (United States); Pauling, Alan K. [Cornell University, Cornell High Energy Synchrotron Source, Ithaca 14850, NY (United States)

    2011-09-01

    At CHESS' A, F and G wiggler beam lines three new video beam position monitors (VBPMs) have been commissioned. These new VBPMs utilize X-rays scattered from the graphite filter (A and F line) or from a beryllium window (G-line) as the white wiggler beam passes through them. As the X-rays scatter in all directions from the scattering medium, a slit camera creates an image of the beam's footprint on a fluorescent screen. This image is then viewed by a CCD camera and analyzed using a computer program to calculate the intensity centroid, the beam profile and integrated intensity. These data are delivered to the CHESS signal archiving system for storage and display. The new systems employ digital cameras. These cameras are free of the noise inherent to the analog systems with long video signal connections. As a result, the beam position data delivered by the new systems are more reliable and accurate as shown by beam position traces using different beam position monitors on the same beam line.

  17. A technique for measuring an electron beam close-quote s longitudinal phase space with sub-picosecond resolution

    International Nuclear Information System (INIS)

    Crosson, E.R.; Berryman, K.W.; Richman, B.A.; Smith, T.I.; Swent, R.L.

    1996-01-01

    We have developed a technique for measuring the longitudinal phase space distribution of the Stanford Superconducting Accelerator close-quote s (SCA) electron beam which involves applying tomographic techniques to energy spectra taken as a function of the relative phase between the beam and the accelerating field, and optionally, as a function of the strength of a variable dispersion section in the system. The temporal profile of the beam obtained by projecting the inferred distribution onto the time axis is compared with that obtained from interferometric transition radiation measurements. copyright 1996 American Institute of Physics

  18. Effects of a laser beam profile on Zeeman electromagnetically induced transparency in the Rb buffer gas cell

    International Nuclear Information System (INIS)

    Nikolić, S N; Radonjić, M; Krmpot, A J; Lučić, N M; Zlatković, B V; Jelenković, B M

    2013-01-01

    Electromagnetically induced transparency (EIT) due to Zeeman coherences in the Rb buffer gas cell is studied for different laser beam profiles, laser beam radii and intensities from 0.1 to 10 mW cm −2 . EIT line shapes can be approximated by the Lorentzian for wide Gaussian laser beam (6.5 mm in diameter) if laser intensity is weak and for a Π laser beam profile of the same diameter. Line shapes of EIT become non-Lorentzian for the Gaussian laser beam if it is narrow (1.3 mm in diameter) or if it has a higher intensity. EIT amplitudes and linewidths, for both laser beam profiles of the same diameter, have very similar behaviour regarding laser intensity and Rb cell temperature. EIT amplitudes are maximal at a certain laser beam intensity and this intensity is higher for narrower laser beams. The EIT linewidth estimated at zero laser intensity is about 50 nT or 0.7 kHz, which refers to 1.5 ms relaxation times of Zeeman coherences in 87 Rb atoms in our buffer gas cell. Blocking of the centre of the wide Gaussian laser beam in front of the photo detector yields Lorentzian profiles with a much better contrast to the linewidth ratio for EIT at higher intensities, above ∼2 mW cm −2 . (paper)

  19. A feasibility study of Dynamic Phantom scanner for quality assurance of photon beam profiles at various gantry angles.

    Science.gov (United States)

    Zhang, Yunkai; Hsi, Wen C; Chu, James C H; Bernard, Damian B; Abrams, Ross A

    2005-01-01

    The effect of gantry rotation on beam profiles of photon and electron beams is an important issue in quality assurance for radiotherapy. To address variations in the profiles of photon and electron beams at different gantry angles, a Dynamic Phantom scanner composed of a 20 x 12 x 6 cm3 scanning Lucite block was designed as a cross-beam-profile scanner. To our knowledge, differences between scanned profiles acquired at different gantry angles with a small size Lucite block and those acquired a full-size (60 x 60 x 50 cm3) water phantom have not been previously investigated. We therefore performed a feasibility study for a first prototype Dynamic Phantom scanner without a gantry attachment mount. Radiation beams from a Varian LINAC 21EX and 2100C were used. Photon beams (6 MV and 18 MV) were shaped by either collimator jaws or a Varian 120 Multileaf (MLC) collimator, and electron beams (6 MeV, 12 MeV, and 20 MeV) were shaped by a treatment cone. To investigate the effect on profiles by using a Lucite block, a quantitative comparison of scanned profiles with the Dynamic Phantom and a full-size water phantom was first performed at a 0 degrees gantry angle for both photon and electron beams. For photon beam profiles defined by jaws at 1.0 cm and 5.0 cm depths of Lucite (i.e., at 1.1 cm and 5.7 cm depth of water), a good agreement (less than 1% variation) inside the field edge was observed between profiles scanned with the Dynamic Phantom and with a water phantom. The use of Lucite in the Dynamic Phantom resulted in reduced penumbra width (about 0.5 mm out of 5 mm to 8mm) and reduced (1% to 2%) scatter dose beyond the field edges for both 6 MV and 18 MV beams, compared with the water phantom scanner. For profiles of the MLC-shaped 6 MV photon beam, a similar agreement was observed. For profiles of electron beams scanned at 2.9 cm depth of Lucite (i.e., at 3.3 cm depth of water), larger disagreements in profiles (3% to 4%) and penumbra width (3 mm to 4 mm out of 12 mm

  20. Neutral Probe Beam q-profile measurements in PDX and PBX-M

    International Nuclear Information System (INIS)

    Kugel, H.W.; Gammel, G.M.; Kaita, R.; Reusch, M.F.; Roberts, D.W.

    1988-06-01

    Using the Fast Ion Diagnostic Experiment (FIDE) technique, a Neutral Probe Beam (NPB) can be aimed to inject tangentially to a magnetic surface. The resultant ion orbit shifts, due to conservation of canonical toroidal angular momentum, can be measured with a multi-sightline charge-exchange analyzer to yield direct measurements of radial magnetic flux profiles, current density profiles, the radial position of the magnetic axis, flux surface inner and outer edges, q-profiles, and central-q time dependencies. An extensive error analysis was performed on previous PDX q-measurements in circular plasmas and the resulting estimated contributions of various systematic effects are discussed. Preliminary results of fast ion orbit shift measurements at early times in indented PBX-M plasmas are given. Methods for increasing the absolute experimental precision of similar measurements in progress on PBX-M are discussed. 4 refs., 3 figs

  1. High spatial resolution and high brightness ion beam probe for in-situ elemental and isotopic analysis

    Science.gov (United States)

    Long, Tao; Clement, Stephen W. J.; Bao, Zemin; Wang, Peizhi; Tian, Di; Liu, Dunyi

    2018-03-01

    A high spatial resolution and high brightness ion beam from a cold cathode duoplasmatron source and primary ion optics are presented and applied to in-situ analysis of micro-scale geological material with complex structural and chemical features. The magnetic field in the source as well as the influence of relative permeability of magnetic materials on source performance was simulated using COMSOL to confirm the magnetic field strength of the source. Based on SIMION simulation, a high brightness and high spatial resolution negative ion optical system has been developed to achieve Critical (Gaussian) illumination mode. The ion source and primary column are installed on a new Time-of-Flight secondary ion mass spectrometer for analysis of geological samples. The diameter of the ion beam was measured by the knife-edge method and a scanning electron microscope (SEM). Results show that an O2- beam of ca. 5 μm diameter with a beam intensity of ∼5 nA and an O- beam of ca. 5 μm diameter with a beam intensity of ∼50 nA were obtained, respectively. This design will open new possibilities for in-situ elemental and isotopic analysis in geological studies.

  2. High-resolution altitude profiles of the atmospheric turbulence with PML at the Sutherland Observatory

    Science.gov (United States)

    Catala, L.; Ziad, A.; Fanteï-Caujolle, Y.; Crawford, S. M.; Buckley, D. A. H.; Borgnino, J.; Blary, F.; Nickola, M.; Pickering, T.

    2017-05-01

    With the prospect of the next generation of ground-based telescopes, the extremely large telescopes, increasingly complex and demanding adaptive optics systems are needed. This is to compensate for image distortion caused by atmospheric turbulence and fully take advantage of mirrors with diameters of 30-40 m. This requires a more precise characterization of the turbulence. The Profiler of Moon Limb (PML) was developed within this context. The PML aims to provide high-resolution altitude profiles of the turbulence using differential measurements of the Moon limb position to calculate the transverse spatio-angular covariance of the angle of arrival fluctuations. The covariance of differential image motion for different separation angles is sensitive to the altitude distribution of the seeing. The use of the continuous Moon limb provides a large number of separation angles allowing for the high-resolution altitude of the profiles. The method is presented and tested with simulated data. Moreover, a PML instrument was deployed at the Sutherland Observatory in South Africa in 2011 August. We present here the results of this measurement campaign.

  3. A feasibility study of the Dynamic Phantom scanner for quality assurance of beam profiles at various gantry angles

    Science.gov (United States)

    Zhang, Yunkai; Hsi, Wen C.; Chu, James C.H.; Bernard, Damian B.; Abrams, Ross A.

    2005-01-01

    The effect of gantry rotation on beam profiles of photon and electron beams is an important issue in quality assurance for radiotherapy. To address variations in the profiles of photon and electron beams at different gantry angles, a Dynamic Phantom scanner composed of a 20×12×6 cm3 scanning Lucite block was designed as a cross‐beam‐profile scanner. To our knowledge, differences between scanned profiles acquired at different gantry angles with a small size Lucite block and those acquired a full‐size (60×60×50 cm3) water phantom have not been previously investigated. We therefore performed a feasibility study for a first prototype Dynamic Phantom scanner without a gantry attachment mount. Radiation beams from a Varian LINAC 21EX and 2100C were used. Photon beams (6 MV and 18 MV) were shaped by either collimator jaws or a Varian 120 Multileaf (MLC) collimator, and electron beams (6 MeV, 12 MeV, and 20 MeV) were shaped by a treatment cone. To investigate the effect on profiles by using a Lucite block, a quantitative comparison of scanned profiles with the Dynamic Phantom and a full‐size water phantom was first performed at a 0° gantry angle for both photon and electron beams. For photon beam profiles defined by jaws at 1.0 cm and 5.0 cm depths of Lucite (i.e., at 1.1 cm and 5.7 cm depth of water), a good agreement (less than 1% variation) inside the field edge was observed between profiles scanned with the Dynamic Phantom and with a water phantom. The use of Lucite in the Dynamic Phantom resulted in reduced penumbra width (about 0.5 mm out of 5 mm to 8 mm) and reduced (1% to 2%) scatter dose beyond the field edges for both 6 MV and 18 MV beams, compared with the water phantom scanner. For profiles of the MLC‐shaped 6 MV photon beam, a similar agreement was observed. For profiles of electron beams scanned at 2.9 cm depth of Lucite (i.e., at 3.3 cm depth of water), larger disagreements in profiles (3% to 4%) and penumbra width (3 mm to 4 mm out of 12 mm

  4. Evaluation of the 3-GeV proton beam profile at the spallation target of the JSNS

    Energy Technology Data Exchange (ETDEWEB)

    Meigo, Shin-ichiro [Japan Atomic Energy Research Institute, Tokai, Naka-gun, Ibaraki 319-1195 (Japan)]. E-mail: meigo.shinichiro@jaea.go.jp; Noda, Fumiaki [Japan Atomic Energy Research Institute, Tokai, Naka-gun, Ibaraki 319-1195 (Japan); Ishikura, Syuichi [Japan Atomic Energy Research Institute, Tokai, Naka-gun, Ibaraki 319-1195 (Japan); Futakawa, Masatoshi [Japan Atomic Energy Research Institute, Tokai, Naka-gun, Ibaraki 319-1195 (Japan); Sakamoto, Shinichi [Japan Atomic Energy Research Institute, Tokai, Naka-gun, Ibaraki 319-1195 (Japan); Ikeda, Yujiro [Japan Atomic Energy Research Institute, Tokai, Naka-gun, Ibaraki 319-1195 (Japan)

    2006-06-23

    At JSNS, 3-GeV protons beam is delivered from rapid cycling synchrotron (RCS) to the spallation neutron target. In order to reduce the damage of pitting on the target container, the peak current density should be kept as small as possible. In this study, the beam profile at spallation neutron target is evaluated. The phase-space distribution, including the space-charge effect, is calculated with SIMPSONS code. The beam profile on the target is obtained with the transfer matrix from exit of RCS to the target. As for injection to RCS, two methods of correlated and anti-correlated painting are considered. By using anti-correlated painting for injection of beam at RCS, it is found the shape of beam becomes flatter than the distribution by using correlated painting. As other aspect for the study of target, in order to carry out target performance test especially for the study of pitting issue, it is better to have the beam profile variety from the beginning of facility. The adjustable range for the beam profile at the beginning is also studied. Although the beam shape is narrow and the duty is very low, the strong enough peak density is achievable equivalent as 1 MW.

  5. Dynamic wedge, electron energy and beam profile Q.A. using an ionization chamber linear array

    International Nuclear Information System (INIS)

    Kenny, M.B.; Todd, S.P.

    1996-01-01

    Since the introduction of multi-modal linacs the quality assurance workload of a Physical Sciences department has increased dramatically. The advent of dynamic wedges has further complicated matters because of the need to invent accurate methods to perform Q.A. in a reasonable time. We have been using an ionization chamber linear array, the Thebes 7000 TM by Victoreen, Inc., for some years to measure X-ray and electron beam profiles. Two years ago we developed software to perform Q.A. on our dynamic wedges using the array and more recently included a routine to check electron beam energies using the method described by Rosenow, U.F. et al., Med. Phys. 18(1) 19-25. The integrated beam and profile management system has enabled us to maintain a comprehensive quality assurance programme on all our linaccs. Both our efficiency and accuracy have increased to the point where we are able to keep up with the greater number of tests required without an increase in staff or hours spent in quality assurance. In changing the processor from the Z80 of the Thebes console to the 486 of the PC we have also noticed a marked increase in the calibration stability of the array. (author)

  6. Image-based motion compensation for high-resolution extremities cone-beam CT

    Science.gov (United States)

    Sisniega, A.; Stayman, J. W.; Cao, Q.; Yorkston, J.; Siewerdsen, J. H.; Zbijewski, W.

    2016-03-01

    Purpose: Cone-beam CT (CBCT) of the extremities provides high spatial resolution, but its quantitative accuracy may be challenged by involuntary sub-mm patient motion that cannot be eliminated with simple means of external immobilization. We investigate a two-step iterative motion compensation based on a multi-component metric of image sharpness. Methods: Motion is considered with respect to locally rigid motion within a particular region of interest, and the method supports application to multiple locally rigid regions. Motion is estimated by maximizing a cost function with three components: a gradient metric encouraging image sharpness, an entropy term that favors high contrast and penalizes streaks, and a penalty term encouraging smooth motion. Motion compensation involved initial coarse estimation of gross motion followed by estimation of fine-scale displacements using high resolution reconstructions. The method was evaluated in simulations with synthetic motion (1-4 mm) applied to a wrist volume obtained on a CMOS-based CBCT testbench. Structural similarity index (SSIM) quantified the agreement between motion-compensated and static data. The algorithm was also tested on a motion contaminated patient scan from dedicated extremities CBCT. Results: Excellent correction was achieved for the investigated range of displacements, indicated by good visual agreement with the static data. 10-15% improvement in SSIM was attained for 2-4 mm motions. The compensation was robust against increasing motion (4% decrease in SSIM across the investigated range, compared to 14% with no compensation). Consistent performance was achieved across a range of noise levels. Significant mitigation of artifacts was shown in patient data. Conclusion: The results indicate feasibility of image-based motion correction in extremities CBCT without the need for a priori motion models, external trackers, or fiducials.

  7. Test beam studies of the light yield, time and coordinate resolutions of scintillator strips with WLS fibers and SiPM readout

    Energy Technology Data Exchange (ETDEWEB)

    Denisov, Dmitri [Fermilab, Batavia IL (United States); Evdokimov, Valery [Institute for High Energy Physics, Protvino (Russian Federation); Lukić, Strahinja; Ujić, Predrag [Vinča Institute, University of Belgrade (Serbia)

    2017-03-11

    Prototype scintilator+WLS strips with SiPM readout for large muon detection systems were tested in the muon beam of the Fermilab Test Beam Facility. Light yield of up to 137 photoelectrons per muon per strip has been observed , as well as time resolution of 330 ps and position resolution along the strip of 5.4 cm.

  8. Minimal interference beam size/profile measurement techniques applicable to the Collider

    International Nuclear Information System (INIS)

    Nexsen, W.; Dutt, S.; Kauffmann, S.; Lebedev, V.; Maschke, A.; Mokhov, N.; Richardson, R.; Tsyganov, E.; Zinchenko, A.

    1993-05-01

    The imaging of synchrotron radiation (SR) has been suggested as a technique for providing a continuous, non-interfering monitor of the beam profile in the Collider rings at the Superconducting Super Collider. A closer examination has raised questions concerning the applicability of SR imaging in this case because of the diffraction broadening of the image, the requirements for axial space and location in the lattice, and the complexity of the system. We have surveyed the known, alternative, minimal interference techniques for measuring beam size and have evaluated them for possible Collider usage. We conclude that of the approaches that appear feasible, all require at least some development for our usage and that the development of an electron beam probe offers the best promise. We recommend that flying wires be used for cross-checking and calibrating the electron beam probe diagnostic and for luminosity measurements when the highest accuracy is required, but flying wires should not be used as the primary diagnostic because of their limited lifetime

  9. Small-sized monitor of beam current and profile for the proton pulse electrostatic accelerator

    International Nuclear Information System (INIS)

    Getmanov, V.N.

    1985-01-01

    Design and principle of operation of current monitor and beam profile of range-coordinate type are described. Monitor operation peculiarities are discussed using diagnostics of a beam of 330-420 keV electrostatic pulse proton accelerator with a beam current of up to 20 mA, at a current density of up to 23 mA x cm -2 and wth pulse duraton of about 20 μs. The monitor consists of a vacuum-dense foil of 3.0+-0.1 μm in thickness (or 0.81+-0.0x- mg x cm -2 ) two grid electrodes, each containing 12 wires, and as solid copper bottom. Foil serves for chopping off background particles with a path lesser 3.0 μm and stands thermal pulse load up to 0.5 J/cm -2 . Grid electrode wires are oriented perpendicularly to lach other and form a two-coordinate secondary-emisson roughness indicator. The bothhom is used for measuring an absolute value of beam current

  10. Electron Energy Resolution of the ATLAS TILECAL Modules with Flat Filter Method (July 2002 test beam)

    CERN Document Server

    Kulchitskii, Yu A; Vinogradov, V B

    2005-01-01

    The constructed ATLAS detector at the LHC will have the great physics discovery potential, in particular in the detection of a heavy Higgs boson. Calorimeters will play a crucial role in it. It is necessary to have confidence that the calorimeters will perform as expected. With the aim of understanding of performance of the ATLAS Tile hadronic calorimeter to electrons 12\\% of modules have been exposed in electron beams with various energies by three possible ways: cell-scan at $\\theta =20^o$ at the centers of the front face cells, $\\eta$-scan and tilerow scan at $\\theta = 90^o$ for the module side cells. We have extracted the electron energy resolutions of the $EBM-$ (ANL-44), $EBM+$ (IFA-42) and $BM$ (JINR-55) Modules of the ATLAS Tile Calorimeter at energies E = 10, 20, 50, 100 and 180 GeV and $\\theta = 20^o$ and $90^o $ and $\\eta$ scan from the July 2002 testbeam run data using the flat filter method of the PMT signal reconstruction. We have determined the statistical and constant terms for the electron en...

  11. Electron Energy Resolution of the ATLAS TILECAL Modules with Fit Filter Method (July 2002 test beam)

    CERN Document Server

    Kulchitskii, Yu A; Vinogradov, V B

    2006-01-01

    The constructed ATLAS detector at the LHC will have the great physics discovery potential, in particular in the detection of a heavy Higgs boson. Calorimeters will play a crucial role in it. It is necessary to have confidence that the calorimeters will perform as expected. With the aim of understanding of performance of the ATLAS Tile hadronic calorimeter to electrons 12\\% of modules have been exposed in electron beams with various energies by three possible ways: cell-scan at $\\theta =20^o$ at the centers of the front face cells, $\\eta$-scan and tilerow scan at $\\theta = 90^o$ for the module side cells. We have extracted the electron energy resolutions of the $EBM-$ (ANL-44), $EBM+$ (IFA-42) and $BM$ (JINR-55) Modules of the ATLAS Tile Calorimeter at energies E = 10, 20, 50, 100 and 180 GeV and $\\theta = 20^o$ and $90^o $ and $\\eta$ scan from the July 2002 testbeam run data using the fit filter method of the PMT signal reconstruction. We have determined the statistical and constant terms for the electron ene...

  12. Active beam position stabilization of pulsed lasers for long-distance ion profile diagnostics at the Spallation Neutron Source (SNS).

    Science.gov (United States)

    Hardin, Robert A; Liu, Yun; Long, Cary; Aleksandrov, Alexander; Blokland, Willem

    2011-02-14

    A high peak-power Q-switched laser has been used to monitor the ion beam profiles in the superconducting linac at the Spallation Neutron Source (SNS). The laser beam suffers from position drift due to movement, vibration, or thermal effects on the optical components in the 250-meter long laser beam transport line. We have designed, bench-tested, and implemented a beam position stabilization system by using an Ethernet CMOS camera, computer image processing and analysis, and a piezo-driven mirror platform. The system can respond at frequencies up to 30 Hz with a high position detection accuracy. With the beam stabilization system, we have achieved a laser beam pointing stability within a range of 2 μrad (horizontal) to 4 μrad (vertical), corresponding to beam drifts of only 0.5 mm × 1 mm at the furthest measurement station located 250 meters away from the light source.

  13. Ground-based lidar and microwave radiometry synergy for high vertical resolution absolute humidity profiling

    Science.gov (United States)

    Barrera-Verdejo, María; Crewell, Susanne; Löhnert, Ulrich; Orlandi, Emiliano; Di Girolamo, Paolo

    2016-08-01

    Continuous monitoring of atmospheric humidity profiles is important for many applications, e.g., assessment of atmospheric stability and cloud formation. Nowadays there are a wide variety of ground-based sensors for atmospheric humidity profiling. Unfortunately there is no single instrument able to provide a measurement with complete vertical coverage, high vertical and temporal resolution and good performance under all weather conditions, simultaneously. For example, Raman lidar (RL) measurements can provide water vapor with a high vertical resolution, albeit with limited vertical coverage, due to sunlight contamination and the presence of clouds. Microwave radiometers (MWRs) receive water vapor information throughout the troposphere, though their vertical resolution is poor. In this work, we present an MWR and RL system synergy, which aims to overcome the specific sensor limitations. The retrieval algorithm combining these two instruments is an optimal estimation method (OEM), which allows for an uncertainty analysis of the retrieved profiles. The OEM combines measurements and a priori information, taking the uncertainty of both into account. The measurement vector consists of a set of MWR brightness temperatures and RL water vapor profiles. The method is applied to a 2-month field campaign around Jülich (Germany), focusing on clear sky periods. Different experiments are performed to analyze the improvements achieved via the synergy compared to the individual retrievals. When applying the combined retrieval, on average the theoretically determined absolute humidity uncertainty is reduced above the last usable lidar range by a factor of ˜ 2 with respect to the case where only RL measurements are used. The analysis in terms of degrees of freedom per signal reveal that most information is gained above the usable lidar range, especially important during daytime when the lidar vertical coverage is limited. The retrieved profiles are further evaluated using

  14. Measurement of surface temperature profiles on liquid uranium metal during electron beam evaporation

    Energy Technology Data Exchange (ETDEWEB)

    Ohba, Hironori; Shibata, Takemasa [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-11-01

    Surface temperature distributions of liquid uranium in a water-cooled copper crucible during electron beam evaporation were measured. Evaporation surface was imaged by a lens through a band-path filter (650{+-}5 nm) and a double mirror system on a charge coupled device (CCD) camera. The video signals of the recorded image were connected to an image processor and converted to two-dimensional spectral radiance profiles. The surface temperatures were obtained from the spectral radiation intensity ratio of the evaporation surface and a freezing point of uranium and/or a reference light source using Planck`s law of radiation. The maximum temperature exceeded 3000 K and had saturation tendency with increasing electron beam input. The measured surface temperatures agreed with those estimated from deposition rates and data of saturated vapor pressure of uranium. (author)

  15. Production of custom beam profiles in computer-controlled radiation therapy

    International Nuclear Information System (INIS)

    Lane, R.G.; Loyd, M.D.; Chow, C.H.; Ekwelundu, E.; Rosen, I.I.

    1989-01-01

    This paper presents a study to produce custom beam profiles in patients that compensate for variations in patient anatomy and achieve uniform dose distributions in the treatment volume. A conventional treatment field is supplemented by a number of centered and/or offset smaller coincident fields of various sizes. The sizes and positions of these supplemental fields and the doses delivered by them are designed to compensate for variations in external patient contour, internal heterogeneities, and variation in tumor volume shape. A computer-controlled linear accelerator with four independent collimator jaws, a built-in motorized wedge filter, an automatic setup capability, and a patient prescription database is used to deliver these complex treatments automatically by means of multiple overlapping beams. Calculations, measurements, and dose distributions demonstrate the efficacy of this technique

  16. Electron density profile determination by means of laser blow-off injected neutral beam

    International Nuclear Information System (INIS)

    Kocsis, G.; Bakos, J.S.; Ignacz, P.N.; Kardon, B.; Koltai, L.; Veres, G.

    1992-01-01

    This paper is devoted to the experimental and theoretical studies of the determination of the electron density profiles by means of laser blow-off neutrals. For the determination of the density profile the time and spatial distributions of the spectral line radiation intensity of the injected neutrals are used. The method is compared to other previously proposed methods and the advantages and disadvantages of the different methods are discussed. The result of the comparison is that our method gives the most reliable result with the highest temporal resolution for the density profile of the edge plasma. The only disadvantage is the need of careful calibration of the sensitivity of the spatial channels. The advantage is the ability of the method as a standard diagnostic. (orig.)

  17. Design of UHV chamber assembly and mirror mounts for high resolution VUV beam line at INDUS-1

    International Nuclear Information System (INIS)

    Saksena, G.D.; Sinha, A.K.; Bhattacharya, S.S.

    1993-01-01

    The reflecting optical system is designed for the high resolution VUV spectroscopy facility to be installed at INDUS-1. The fore-optics system consists of three cylindrical mirrors (M1, M2 and M3) to accept a 60 mrad (horizontal) x 6 mrad (vertical) diverging synchrotron beam from the storage ring in order to focus the image on the entrance slit of the vacuum spectrometer located at 13 m from the source point. In this paper we present some important details regarding mechanical design of the high resolution beam line consisting of mirror mounts, UHV chambers, associated mechanisms and beam pipes. The mirrors are mounted in an adjustable three point kinematic holder. In addition, these mounts are provided with a multi-plane alignment provision. Mirror mounts are placed inside VHV chambers which are provided with three translational and two rotational movements to facilitate initial as well as final on-line fine-tuned alignments. Beam pipes are connected to the VHV chambers through flanged bellows. Chambers, associated mechanisms, beam pipes with its non-rigid support and related pumping stations are positioned in the support structure rigidly. (author). 2 figs

  18. Design of the beam profile monitor system for the RHIC injection line

    International Nuclear Information System (INIS)

    Witkover, R.L.

    1995-01-01

    A video profile monitor (VPM) system will be used in the AGS-to-RHIC (ATR) transfer line to acquire single bunches transferred at 30 Hz. An array of 12 video cameras will be connected to 4 frame grabbers through a wide-band flux. Fast VME image processing boards will analyze a 120 x 120 subset of the image, generated by a 4 x 4 convolution or an ROI computation and sent over the network during the AGS recycle time. Details of the design, results of lab tests and studies with ion and proton beams will be presented

  19. Design and fabrication of continuous-profile diffractive micro-optical elements as a beam splitter.

    Science.gov (United States)

    Feng, Di; Yan, Yingbai; Jin, Guofan; Fan, Shoushan

    2004-10-10

    An optimization algorithm that combines a rigorous electromagnetic computation model with an effective iterative method is utilized to design diffractive micro-optical elements that exhibit fast convergence and better design quality. The design example is a two-dimensional 1-to-2 beam splitter that can symmetrically generate two focal lines separated by 80 microm at the observation plane with a small angle separation of +/- 16 degrees. Experimental results are presented for an element with continuous profiles fabricated into a monocrystalline silicon substrate that has a width of 160 microm and a focal length of 140 microm at a free-space wavelength of 10.6 microm.

  20. Site-selective dopant profiling of p-n junction specimens in the dual-beam FIB/SEM system

    International Nuclear Information System (INIS)

    Chee, K W A; Beanland, R; Midgley, P A; Humphreys, C J

    2010-01-01

    Results from site-specific dopant profiling in a dual-beam FIB/SEM system are reported. Si specimens containing p-n junctions were milled using Ga + ion beam energies ranging from 30 keV to 2 keV, and analysed in situin the vacuum chamber. We compare the dopant contrast observed when milling a cleaved surface to that obtained from a side-wall of a trench cut using 30 kV Ga + ions, and using successively lower ion beam energies. The latter technique is suitable for site-specific dopant profiling. We find that lower energy ion beam milling significantly improves contrast, but only achieves 50 % of that observed on a freshly-cleaved surface. Furthermore, the contrast on a side-wall previously milled using high energy Ga + ions is less than that of a cleaved surface subjected to the same ion beam energy.

  1. Micromachining of commodity plastics by proton beam writing and fabrication of spatial resolution test-chart for neutron radiography

    International Nuclear Information System (INIS)

    Sakai, T.; Yasuda, R.; Iikura, H.; Nojima, T.; Matsubayashi, M.; Kada, W.; Kohka, M.; Satoh, T.; Ohkubo, T.; Ishii, Y.; Takano, K.

    2013-01-01

    Proton beam writing is a direct-write technique and a promising method for the micromachining of commodity plastics such as acrylic resins. Herein, we describe the fabrication of microscopic devices made from a relatively thick (∼75 μm) acrylic sheet using proton beam writing. In addition, a software package that converts image pixels into coordinates data was developed, and the successful fabrication of a very fine jigsaw puzzle was achieved. The size of the jigsaw puzzle pieces was 50 × 50 μm. For practical use, a prototype of a line and space test-chart was also successfully fabricated for the determination of spatial resolution in neutron radiography

  2. Combined Atmospheric and Ocean Profiling from an Airborne High Spectral Resolution Lidar

    Directory of Open Access Journals (Sweden)

    Hair Johnathan

    2016-01-01

    Full Text Available First of its kind combined atmospheric and ocean profile data were collected by the recently upgraded NASA Langley Research Center’s (LaRC High Spectral Resolution Lidar (HSRL-1 during the 17 July – 7 August 2014 Ship-Aircraft Bio-Optical Research Experiment (SABOR. This mission sampled over a region that covered the Gulf of Maine, open-ocean near Bermuda, and coastal waters from Virginia to Rhode Island. The HSRL-1 and the Research Scanning Polarimeter from NASA Goddard Institute for Space Studies collected data onboard the NASA LaRC King Air aircraft and flight operations were closely coordinated with the Research Vessel Endeavor that made in situ ocean optical measurements. The lidar measurements provided profiles of atmospheric backscatter and particulate depolarization at 532nm, 1064nm, and extinction (532nm from approximately 9km altitude. In addition, for the first time HSRL seawater backscatter, depolarization, and diffuse attenuation data at 532nm were collected and compared to both the ship measurements and the Moderate Resolution Imaging Spectrometer (NASA MODIS-Aqua satellite ocean retrievals.

  3. Degradation effects ad Si-depth profiling in photoresists using ion beam analysis

    International Nuclear Information System (INIS)

    Ijzendoorn, L.J. van; Schellekens, J.P.W.

    1989-01-01

    The reaction of silicon-containing vapour with a photoresist layer, as used in dry developable lithographic processes, was studied with Rutherford backscattering spectrometry (RBS). Degradation of the polymer layer was observed, but the total amount of incorporated Si was found to be constant during the measurement. Si-depth profiles were found to be independent of dose and in agreement with profiles obtained with secondary ion mass spectrometry (SIMS). The detection of hydrogen by elastic recoil detection (ERD) was used to study the degradation in detail. The decrease in hydrogen countrate from a layer of polystyrene on Si in combination with the shift of the Si-substrate edge in the corresponding RBS spectra was used for a model description. Only one degradation cross-section for hydrogen and one for carbon, both independent of beam current and dose, were required for a successful fit of the experimental data. (orig.)

  4. X-ray beam-shaping via deformable mirrors: Analytical computation of the required mirror profile

    International Nuclear Information System (INIS)

    Spiga, Daniele; Raimondi, Lorenzo; Svetina, Cristian; Zangrando, Marco

    2013-01-01

    X-ray mirrors with high focusing performances are in use in both mirror modules for X-ray telescopes and in synchrotron and FEL (Free Electron Laser) beamlines. A degradation of the focus sharpness arises in general from geometrical deformations and surface roughness, the former usually described by geometrical optics and the latter by physical optics. In general, technological developments are aimed at a very tight focusing, which requires the mirror profile to comply with the nominal shape as much as possible and to keep the roughness at a negligible level. However, a deliberate deformation of the mirror can be made to endow the focus with a desired size and distribution, via piezo actuators as done at the EIS-TIMEX beamline of FERMI@Elettra. The resulting profile can be characterized with a Long Trace Profilometer and correlated with the expected optical quality via a wavefront propagation code. However, if the roughness contribution can be neglected, the computation can be performed via a ray-tracing routine, and, under opportune assumptions, the focal spot profile (the Point Spread Function, PSF) can even be predicted analytically. The advantage of this approach is that the analytical relation can be reversed; i.e., from the desired PSF the required mirror profile can be computed easily, thereby avoiding the use of complex and time-consuming numerical codes. The method can also be suited in the case of spatially inhomogeneous beam intensities, as commonly experienced at synchrotrons and FELs. In this work we expose the analytical method and the application to the beam shaping problem

  5. Semi-empirical procedures for correcting detector size effect on clinical MV x-ray beam profiles

    International Nuclear Information System (INIS)

    Sahoo, Narayan; Kazi, Abdul M.; Hoffman, Mark

    2008-01-01

    The measured radiation beam profiles need to be corrected for the detector size effect to derive the real profiles. This paper describes two new semi-empirical procedures to determine the real profiles of high-energy x-ray beams by removing the detector size effect from the measured profiles. Measured profiles are corrected by shifting the position of each measurement point by a specific amount determined from available theoretical and experimental knowledge in the literature. The authors developed two procedures to determine the amount of shift. In the first procedure, which employs the published analytical deconvolution procedure of other investigators, the shift is determined from the comparison of the analytical fit of the measured profile and the corresponding analytical real profile derived from the deconvolution of the fitted measured profile and the Gaussian detector response function. In the second procedure, the amount of shift at any measurement point is considered to be proportional to the value of an analytical function related to the second derivative of the real profile at that point. The constant of proportionality and a parameter in the function are obtained from the values of the shifts at the 90%, 80%, 20%, and 10% dose levels, which are experimentally known from the published results of other investigators to be approximately equal to half of the radius of the detector. These procedures were tested by correcting the profiles of 6 and 18 MV x-ray beams measured by three different ionization chambers and a stereotactic field diode detector with 2.75, 2, 1, and 0.3 mm radii of their respective active cylindrical volumes. The corrected profiles measured by different detectors are found to be in close agreement. The detector size corrected penumbra widths also agree with the expected values based on the results of an earlier investigation. Thus, the authors concluded that the proposed procedures are accurate and can be used to derive the real

  6. Parallel-hierarchical processing and classification of laser beam profile images based on the GPU-oriented architecture

    Science.gov (United States)

    Yarovyi, Andrii A.; Timchenko, Leonid I.; Kozhemiako, Volodymyr P.; Kokriatskaia, Nataliya I.; Hamdi, Rami R.; Savchuk, Tamara O.; Kulyk, Oleksandr O.; Surtel, Wojciech; Amirgaliyev, Yedilkhan; Kashaganova, Gulzhan

    2017-08-01

    The paper deals with a problem of insufficient productivity of existing computer means for large image processing, which do not meet modern requirements posed by resource-intensive computing tasks of laser beam profiling. The research concentrated on one of the profiling problems, namely, real-time processing of spot images of the laser beam profile. Development of a theory of parallel-hierarchic transformation allowed to produce models for high-performance parallel-hierarchical processes, as well as algorithms and software for their implementation based on the GPU-oriented architecture using GPGPU technologies. The analyzed performance of suggested computerized tools for processing and classification of laser beam profile images allows to perform real-time processing of dynamic images of various sizes.

  7. High-resolution geophysical profiling using a stepped-frequency ground penetrating radar

    Energy Technology Data Exchange (ETDEWEB)

    Noon, D; Longstaff, D [The University of Queensland, (Australia)

    1996-05-01

    This paper describes the results of a ground penetrating radar (GPR) system which uses stepped-frequency waveforms to obtain high-resolution geophysical profiles. The main application for this system is the high-resolution mapping of thin coal seam structures, in order to assist surface mining operations in open-cut coal mines. The required depth of penetration is one meter which represents the maximum thickness of coal seams that are designated `thin`. A resolution of five centimeters is required to resolve the minimum thickness of coal (or shale partings) which can be economically recovered in an open-cut coal mine. For this application, a stepped-frequency GPR system has been developed, because of its ultrawide bandwidth (1 to 2 GHz) and high external loop sensitivity (155 dB). The field test results of the stepped-frequency GPR system on a concrete pavement and at two Australian open-cut coal mines are also presented. 7 refs., 5 figs.

  8. Improved laser-based triangulation sensor with enhanced range and resolution through adaptive optics-based active beam control.

    Science.gov (United States)

    Reza, Syed Azer; Khwaja, Tariq Shamim; Mazhar, Mohsin Ali; Niazi, Haris Khan; Nawab, Rahma

    2017-07-20

    Various existing target ranging techniques are limited in terms of the dynamic range of operation and measurement resolution. These limitations arise as a result of a particular measurement methodology, the finite processing capability of the hardware components deployed within the sensor module, and the medium through which the target is viewed. Generally, improving the sensor range adversely affects its resolution and vice versa. Often, a distance sensor is designed for an optimal range/resolution setting depending on its intended application. Optical triangulation is broadly classified as a spatial-signal-processing-based ranging technique and measures target distance from the location of the reflected spot on a position sensitive detector (PSD). In most triangulation sensors that use lasers as a light source, beam divergence-which severely affects sensor measurement range-is often ignored in calculations. In this paper, we first discuss in detail the limitations to ranging imposed by beam divergence, which, in effect, sets the sensor dynamic range. Next, we show how the resolution of laser-based triangulation sensors is limited by the interpixel pitch of a finite-sized PSD. In this paper, through the use of tunable focus lenses (TFLs), we propose a novel design of a triangulation-based optical rangefinder that improves both the sensor resolution and its dynamic range through adaptive electronic control of beam propagation parameters. We present the theory and operation of the proposed sensor and clearly demonstrate a range and resolution improvement with the use of TFLs. Experimental results in support of our claims are shown to be in strong agreement with theory.

  9. Visualization and analysis of pulsed ion beam energy density profile with infrared imaging

    Science.gov (United States)

    Isakova, Y. I.; Pushkarev, A. I.

    2018-03-01

    Infrared imaging technique was used as a surface temperature-mapping tool to characterize the energy density distribution of intense pulsed ion beams on a thin metal target. The technique enables the measuring of the total ion beam energy and the energy density distribution along the cross section and allows one to optimize the operation of an ion diode and control target irradiation mode. The diagnostics was tested on the TEMP-4M accelerator at TPU, Tomsk, Russia and on the TEMP-6 accelerator at DUT, Dalian, China. The diagnostics was applied in studies of the dynamics of the target cooling in vacuum after irradiation and in the experiments with target ablation. Errors caused by the target ablation and target cooling during measurements have been analyzed. For Fluke Ti10 and Fluke Ti400 infrared cameras, the technique can achieve surface energy density sensitivity of 0.05 J/cm2 and spatial resolution of 1-2 mm. The thermal imaging diagnostics does not require expensive consumed materials. The measurement time does not exceed 0.1 s; therefore, this diagnostics can be used for the prompt evaluation of the energy density distribution of a pulsed ion beam and during automation of the irradiation process.

  10. Experimental determination of the lateral dose response functions of detectors to be applied in the measurement of narrow photon-beam dose profiles.

    Science.gov (United States)

    Poppinga, D; Meyners, J; Delfs, B; Muru, A; Harder, D; Poppe, B; Looe, H K

    2015-12-21

    This study aims at the experimental determination of the detector-specific 1D lateral dose response function K(x) and of its associated rotational symmetric counterpart K(r) for a set of high-resolution detectors presently used in narrow-beam photon dosimetry. A combination of slit-beam, radiochromic film, and deconvolution techniques served to accomplish this task for four detectors with diameters of their sensitive volumes ranging from 1 to 2.2 mm. The particular aim of the experiment was to examine the existence of significant negative portions of some of these response functions predicted by a recent Monte-Carlo-simulation (Looe et al 2015 Phys. Med. Biol. 60 6585-607). In a 6 MV photon slit beam formed by the Siemens Artiste collimation system and a 0.5 mm wide slit between 10 cm thick lead blocks serving as the tertiary collimator, the true cross-beam dose profile D(x) at 3 cm depth in a large water phantom was measured with radiochromic film EBT3, and the detector-affected cross-beam signal profiles M(x) were recorded with a silicon diode, a synthetic diamond detector, a miniaturized scintillation detector, and a small ionization chamber. For each detector, the deconvolution of the convolution integral M(x)  =  K(x)  ∗  D(x) served to obtain its specific 1D lateral dose response function K(x), and K(r) was calculated from it. Fourier transformations and back transformations were performed using function approximations by weighted sums of Gaussian functions and their analytical transformation. The 1D lateral dose response functions K(x) of the four types of detectors and their associated rotational symmetric counterparts K(r) were obtained. Significant negative curve portions of K(x) and K(r) were observed in the case of the silicon diode and the diamond detector, confirming the Monte-Carlo-based prediction (Looe et al 2015 Phys. Med. Biol. 60 6585-607). They are typical for the perturbation of the secondary electron field by a detector with

  11. Design, construction and beam tests of the high resolution uranium scintillator calorimeter for ZEUS

    International Nuclear Information System (INIS)

    Straver, J.A.

    1991-01-01

    HERA will collide protons and electrons with energies up to 820 GeV and 30 GeV respectively. Therefore it allows measurements at momentum transfers (Q) which greatly surpass the investigations carried out so far. This extended range in Q will allow investigation of the interactions between the quarks and leptons at a distance scale of the order of 10 -18 cm. Two detectors are foreseen at HERA H1 and ZEUS. The design of the ZEUS detector is optimized for the study of neutral and charged current interactions. A calorimeter is a detector which absorbs the total incident energy of a particle while generating a signal proportional to this energy. The ZEUS calorimeter is built of alternating layers of dense absorber plates ( 238 U) and active layers of scintillator material with a fast readout system via wavelength shifters, light guides and photomultiplyers. The main subject of this thesis is the description of this calorimeter and its performance. After a short introduction to HERA and the physics topics, the importance of the quality of a calorimeter is pointed out and a brief overview of the ZEUS detector is given. In ch. 3 the principles of high resolution hadron calorimetry and the studies which led to the design of the ZEUS-calorimeter are discussed. Ch. 4 describes the mechanical design of the ZEUS forward calorimeter, the mechanical finite element calculations, and the production of the calorimeter modules at NIKHEF. Finally ch. 6 and 5 show the results of beam tests of the ZEUS forward calorimeter prototypes and the final full size forward calorimeter modules. (author). 59 refs.; 115 figs.; 29 tabs

  12. Three-rooted premolar analyzed by high-resolution and cone beam CT.

    Science.gov (United States)

    Marca, Caroline; Dummer, Paul M H; Bryant, Susan; Vier-Pelisser, Fabiana Vieira; Só, Marcus Vinicius Reis; Fontanella, Vania; Dutra, Vinicius D'avila; de Figueiredo, José Antonio Poli

    2013-07-01

    The aim of this study was to analyze the variations in canal and root cross-sectional area in three-rooted maxillary premolars between high-resolution computed tomography (μCT) and cone beam computed tomography (CBCT). Sixteen extracted maxillary premolars with three distinct roots and fully formed apices were scanned using μCT and CBCT. Photoshop CS software was used to measure root and canal cross-sectional areas at the most cervical and the most apical points of each root third in images obtained using the two tomographic computed (CT) techniques, and at 30 root sections equidistant from both root ends using μCT images. Canal and root areas were compared between each method using the Student t test for paired samples and 95 % confidence intervals. Images using μCT were sharper than those obtained using CBCT. There were statistically significant differences in mean area measurements of roots and canals between the μCT and CBCT techniques (P < 0.05). Root and canal areas had similar variations in cross-sectional μCT images and became proportionally smaller in a cervical to apical direction as the cementodentinal junction was approached, from where the area then increased apically. Although variation was similar in the roots and canals under study, CBCT produced poorer image details than μCT. Although CBCT is a strong diagnosis tool, it still needs improvement to provide accuracy in details of the root canal system, especially in cases with anatomical variations, such as the three-rooted maxillary premolars.

  13. Gene Expression Profile of Proton Beam Irradiated Breast Cancer Stem Cells

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Myung Hwan; Park, Jeong Chan [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    Cancer stem cells (CSCs) possess characteristics associated with normal stem cells. The mechanisms regulating CSC radio-resistance, including to proton beam, remain unclear. They showed that a subset of cells expressing CD44 with weak or no CD24 expression could establish new tumors in xenograft mice. Recently, BCSC-targeting therapies have been evaluated by numerous groups. Strategies include targeting BCSC self-renewal, indirectly targeting the microenvironment, and directly killing BCSCs by chemical agents that induce differentiation, immunotherapy, and oncolytic viruses. However, the mechanisms regulating CSC radio-resistance, particularly proton beam resistance, remain unclear. The identification of CSC-related gene expression patterns would make up offer data for better understanding CSCs properties. In this study we investigated the gene expression profile of BCSCs isolation from MCF-7 cell line. Reducing BCSC resistance to pulsed proton beams is essential to improve therapeutic efficacy and decrease the 5-year recurrence rate. In this respect, the information of the level of gene expression patterns in BCSCs is attractive for understanding molecular mechanisms of radio-resistance of BCSCs.

  14. Accurate Profile Measurement of the low Intensity Secondary Beams in the CERN Experimental Areas

    CERN Document Server

    AUTHOR|(CDS)2084531; Tranquille, Gerard

    2018-02-23

    The CERN accelerators deliver a wide spectrum of secondary beams to the Experimental Areas. These beams are composed of hadrons, leptons, and heavy ions that can vary greatly in momentum (1 GeV/c to 400 GeV/c) and intensity (10^2 to 10^8 particles per second). The profile, position, and intensity of these beams are measured utilising particle detectors. However, the current systems show several problems that limit the quality of this kind of monitoring. The aim of this doctoral thesis is to investigate the best detector technology that could replace the existing monitors and build a first prototype of it. A review of the existing detection techniques has led to the choice of Scintillating Fibres (SciFi) read-out with Silicon Photomultipliers (SiPM). This detection technology has the potential to perform better in terms of material budget, range of intensities measured, and active area size. In addition, it has particle counting capabilities, which could extend its application to momentum spectrometry or Time...

  15. Initial time-resolved particle beam profile measurements at the Advanced Photon Source

    International Nuclear Information System (INIS)

    Yang, B.X.; Lumpkin, A.H.

    1995-01-01

    The commissioning of the 7-GeV Advanced Photon Source (APS) storage ring began in early 1995. Characterization of the stored particle beam properties involved time-resolved transverse and longitudinal profile measurements using optical synchrotron radiation (OSR) monitors. Early results include the observation of the beam on a single turn, measurements of the transverse beam sizes after damping using a 100 μs integration time (σ x ∼ 150 ± 25 μm, σ γ ∼ 65 ± 25 μm, depending on vertical coupling), and measurement of the bunch length (σ τ ∼ 25 to 55 ps, depending on the charge per bunch). The results are consistent with specifications and predictions based on the 8.2 nm-rad natural emittance, the calculated lattice parameters, and vertical coupling less than 10%. The novel, single-element focusing mirror for the photon transport line and the dual-sweep streak camera techniques which allow turn-by-turn measurements will also be presented. The latter measurements are believed to be the first of their kind on a storage ring in the USA

  16. Studying wedge factors and beam profiles for physical and enhanced dynamic wedges

    Directory of Open Access Journals (Sweden)

    Ahmad Misbah

    2010-01-01

    Full Text Available This study was designed to investigate variation in Varian′s Physical and Enhanced Dynamic Wedge Factors (WF as a function of depth and field size. The profiles for physical wedges (PWs and enhanced dynamic wedges (EDWs were also measured using LDA-99 array and compared for confirmation of EDW angles at different depths and field sizes. WF measurements were performed in water phantom using cylindrical 0.66 cc ionization chamber. WF was measured by taking the ratio of wedge and open field ionization data. A normalized wedge factor (NWF was introduced to circumvent large differences between wedge factors for different wedge angles. A strong linear dependence of PW Factor (PWF with depth was observed. Maximum variation of 8.9% and 4.1% was observed for 60° PW with depth at 6 and 15 MV beams respectively. The variation in EDW Factor (EDWF with depth was almost negligible and less than two per cent. The highest variation in PWF as a function of field size was 4.1% and 3.4% for thicker wedge (60° at 6 and 15 MV beams respectively and decreases with decreasing wedge angle. EDWF shows strong field size dependence and significant variation was observed for all wedges at both photon energies. Differences in profiles between PW and EDW were observed on toe and heel sides. These differences were dominant for larger fields, shallow depths, thicker wedges and low energy beam. The study indicated that ignoring depth and field size dependence of WF may result in under/over dose to the patient especially doing manual point dose calculation.

  17. Studies of the Influence of Beam Profile and Cooling Conditions on the Laser Deposition of a Directionally-Solidified Superalloy

    Directory of Open Access Journals (Sweden)

    Shuo Yang

    2018-02-01

    Full Text Available In the laser deposition of single crystal and directionally-solidified superalloys, it is desired to form laser deposits with high volume fractions of columnar grains by suppressing the columnar-to-equiaxed transition efficiently. In this paper, the influence of beam profile (circular and square shapes and cooling conditions (natural cooling and forced cooling on the geometric morphology and microstructure of deposits were experimentally studied in the laser deposition of a directionally-solidified superalloy, IC10, and the mechanisms of influence were revealed through a numerical simulation of the thermal processes during laser deposition. The results show that wider and thinner deposits were obtained with the square laser beam than those with the circular laser beam, regardless of whether natural or forced cooling conditions was used. The heights and contact angles of deposits were notably increased due to the reduced substrate temperatures by the application of forced cooling for both laser beam profiles. Under natural cooling conditions, columnar grains formed epitaxially at both the center and the edges of the deposits with the square laser beam, but only at the center of the deposits with the circular laser beam; under forced cooling conditions, columnar grains formed at both the center and the edges of deposits regardless of the laser beam profile. The high ratios of thermal gradient and solidification velocity in the height direction of the deposits were favorable to forming deposits with higher volume fractions of columnar grains.

  18. High-resolution profiles of sodium and potassium lines in alpha Orionis

    International Nuclear Information System (INIS)

    Goldberg, L.; Ramsey, L.; Testerman, L.; Carbon, D.

    1975-01-01

    Profiles of the K i resonance line at 7698.98 A and of the D 1 and D 2 lines of Na i in the spectrum of α Ori have been rocorded photoelectrically using the main beam of the McMath solar telescope at KPNO. The Na lines were observed in the fourth order of the spectrograph and the K i line in the third order, providing a resolving power of approximately 50 mA. The observed profiles are consistent with a model in which radiation from the stellar photosphere is scattered and reemitted by an expanding envelope or envelopes of radius large compared with that of the photosphere. Each blueshifted absorption core appears to consist of two components of approximately the same intensity. The first has a heliocentric radial velocity of +11-13 km s -1 , which agrees very well with measurements of other resonance lines by other observers, whereas the second is in the range +4-6 km s -1 and appears not to have been detected previously

  19. High-resolution-cone beam tomography analysis of bone microarchitecture in patients with acromegaly and radiological vertebral fractures.

    Science.gov (United States)

    Maffezzoni, Filippo; Maddalo, Michele; Frara, Stefano; Mezzone, Monica; Zorza, Ivan; Baruffaldi, Fabio; Doglietto, Francesco; Mazziotti, Gherardo; Maroldi, Roberto; Giustina, Andrea

    2016-11-01

    Vertebral fractures are an emerging complication of acromegaly but their prediction is still difficult occurring even in patients with normal bone mineral density. In this study we evaluated the ability of high-resolution cone-beam computed tomography to provide information on skeletal abnormalities associated with vertebral fractures in acromegaly. 40 patients (24 females, 16 males; median age 57 years, range 25-72) and 21 healthy volunteers (10 females, 11 males; median age 60 years, range: 25-68) were evaluated for trabecular (bone volume/trabecular volume ratio, mean trabecular separation, and mean trabecular thickness) and cortical (thickness and porosity) parameters at distal radius using a high-resolution cone-beam computed tomography system. All acromegaly patients were evaluated for morphometric vertebral fractures and for mineral bone density by dual-energy X-ray absorptiometry at lumbar spine, total hip, femoral neck, and distal radius. Acromegaly patients with vertebral fractures (15 cases) had significantly (p acromegaly patients did not have significant differences in bone density at either skeletal site. Patients with acromegaly showed lower bone volume/trabecular volume ratio (p = 0.003) and mean trabecular thickness (p acromegaly. High-resolution cone-beam computed tomography at the distal radius may be useful to evaluate and predict the effects of acromegaly on bone microstructure.

  20. Calibration and energy resolution study of a high dispersive power Thomson Parabola Spectrometer with monochromatic proton beams

    International Nuclear Information System (INIS)

    Schillaci, F.; Cirrone, G.A.P.; Cuttone, G.; Pisciotta, P.; Rifuggiato, D.; Romano, F.; Scuderi, V.; Stancampiano, C.; Tramontana, A.; Amato, A.; Caruso, G.F.; Salamone, S.; Maggiore, M.; Velyhan, A.; Margarone, D.; Palumbo, G. Parasiliti; Russo, G.

    2014-01-01

    A high energy resolution, high dispersive power Thomson Parabola Spectrometer has been developed at INFN-LNS in order to characterize laser-driven beams up to 30- 40 MeV for protons. This device has parallel electric and magnetic field to deflect particles of a certain charge-to-mass ratio onto parabolic traces on the detection plane. Calibration of the deflection sector is crucial for data analysis, namely energy determination of analysed beam, and to evaluate the effective energy limit and resolution. This work reports the study of monochromatic proton beams delivered by the TANDEM accelerator at LNS (Catania) in the energy range between 6 and 12.5 MeV analysed with our spectrometer which allows a precise characterization of the electric and magnetic deflections. Also the energy and the Q/A resolutions and the energy limits have been evaluated proposing a mathematical model that can be used for data analysis, for the experimental set up and for the device scalability for higher energy

  1. TH-CD-201-09: High Spatial Resolution Absorbed Dose to Water Measurements Using Optical Calorimetry in Megavoltage External Beam Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Flores-Martinez, E; DeWerd, L [School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI (United States); Radtke, J [University of Wisconsin, Madison, WI (United States)

    2016-06-15

    Purpose: To develop and implement a high spatial resolution calorimeter methodology to measure absorbed dose to water (ADW) using phase shifts (PSs) of light passing through a water phantom and to compare measurements with theoretical calculations. Methods: Radiation-induced temperature changes were measured using the PSs of a He-Ne laser beam passing through a (10×10×10) cm{sup 3} water phantom. PSs were measured using a Michelson interferometer and recording the time-dependent fringe patterns on a CCD camera. The phantom was positioned at the center of the radiation field. A Varian 21EX was used to deliver 500 MU from a 9 MeV beam using a (6×6) cm{sup 2} cone. A 127cm SSD was used and the PSs were measured at depths ranging from of 1.90cm to 2.10cm in steps of 0.05cm by taking profiles at the corresponding rows across the image. PSs were computed by taking the difference between pre- and post-irradiation image frames and then measuring the amplitude of the resulting image profiles. An amplitude-to-PS calibration curve was generated using a piezoelectric transducer to mechanically induce PSs between 0.05 and 1.50 radians in steps of 0.05 radians. The temperature dependence of the refractive index of water at 632.8nm was used to convert PSs to ADW. Measured results were compared with ADW values calculated using the linac output calibration and commissioning data. Results: Milli-radian resolution in PS measurement was achieved using the described methodology. Measured radiation-induced PSs ranged from 0.10 ± 0.01 to 0.12 ± 0.01 radians at the investigated depths. After converting PSs to ADW, measured and calculated ADW values agreed within the measurement uncertainty. Conclusion: This work shows that interferometer-based calorimetry measurements are capable of achieving sub-millimeter resolution measuring 2D temperature/dose distributions, which are particularly useful for characterizing beams from modalities such as SRS, proton therapy, or microbeams.

  2. Improved mass resolution and mass accuracy in TOF-SIMS spectra and images using argon gas cluster ion beams.

    Science.gov (United States)

    Shon, Hyun Kyong; Yoon, Sohee; Moon, Jeong Hee; Lee, Tae Geol

    2016-06-09

    The popularity of argon gas cluster ion beams (Ar-GCIB) as primary ion beams in time-of-flight secondary ion mass spectrometry (TOF-SIMS) has increased because the molecular ions of large organic- and biomolecules can be detected with less damage to the sample surfaces. However, Ar-GCIB is limited by poor mass resolution as well as poor mass accuracy. The inferior quality of the mass resolution in a TOF-SIMS spectrum obtained by using Ar-GCIB compared to the one obtained by a bismuth liquid metal cluster ion beam and others makes it difficult to identify unknown peaks because of the mass interference from the neighboring peaks. However, in this study, the authors demonstrate improved mass resolution in TOF-SIMS using Ar-GCIB through the delayed extraction of secondary ions, a method typically used in TOF mass spectrometry to increase mass resolution. As for poor mass accuracy, although mass calibration using internal peaks with low mass such as hydrogen and carbon is a common approach in TOF-SIMS, it is unsuited to the present study because of the disappearance of the low-mass peaks in the delayed extraction mode. To resolve this issue, external mass calibration, another regularly used method in TOF-MS, was adapted to enhance mass accuracy in the spectrum and image generated by TOF-SIMS using Ar-GCIB in the delayed extraction mode. By producing spectra analyses of a peptide mixture and bovine serum albumin protein digested with trypsin, along with image analyses of rat brain samples, the authors demonstrate for the first time the enhancement of mass resolution and mass accuracy for the purpose of analyzing large biomolecules in TOF-SIMS using Ar-GCIB through the use of delayed extraction and external mass calibration.

  3. High resolution magnetic force microscopy using focussed ion beam modified tips

    NARCIS (Netherlands)

    Phillips, G.N.; Siekman, Martin Herman; Abelmann, Leon; Lodder, J.C.

    2002-01-01

    Summary form only given. Magnetic force microscopy (MFM) is well established for imaging surface magnetic stray fields. With commercial microscopes and magnetic tips, images with 50 nm resolution are quite routine; however, obtaining higher resolutions is experimentally more demanding. Higher

  4. Monte Carlo investigation of the effect of small cutouts on beam profile parameters of 12 and 14 MeV electron beams

    International Nuclear Information System (INIS)

    Khaledi, Navid; Arbabi, Azim; Sardari, Dariush; Rabie Mahdavi, Seied; Aslian, Hossein; Dabaghi, Moloud; Sheibani, Kourosh

    2013-01-01

    Cutouts, which are used as field-shaping shield, affect several electron beam parameters. These effects are more observable for small field sizes and high energy electron beams. Owing to the fact that small fields prevent the lateral scatter equilibrium, at higher energies larger field radius is required for the establishment of lateral equilibrium. The profile curves are derived from circular, triangular, and square cutout shapes and size placed in a 10 × 10 cm 2 electron applicator. These profile curves are obtained using parallel plane type ion chamber at the R 100 , R 90 , R 80 and R 50 depths. Correspondingly, the source surface distance is 100 cm. In this study MCNP Monte Carlo (MC) simulation was used to compare Percentage Depth Dose (PDD) and Profile of electron beams. Monte Carlo and measured results showed a good compliance for PDD and beam profile. The measurements and calculations showed that as the field width decreases, the Flatness and Penumbra Ratio also decreases. In other words, flatter plateau was available for larger fields. Also the Coverage Ratio for each of the profiles is presented. The flatness and symmetry values for triangle shapes were greater than the two other shapes. Knowledge of these changes are significant in radiation therapy. Accordingly, a comparison between the Monte Carlo data and the measured results can be beneficial for treatment simulation and development of treatment planning systems. - Highlights: ► Mesh Tally 1 and pedep keyword were used to calculate the PDD and profile values. ► In measurement the coverage for larger fields and fewer doses are better. ► By increasing the depth, the flatness and symmetry values were increased. ► The worst flatness and symmetry (between 3 compared shapes) belonged to triangle. ► The given Penumbra and Coverage Ratio can be helpful for PTV margin and coverage

  5. Effective source size, yield and beam profile from multi-layered bremsstrahlung targets

    International Nuclear Information System (INIS)

    Svensson, R.; Brahme, A.

    1996-01-01

    Modern conformal radiotherapy benefits from heterogeneous dose delivery using scanned narrow bremsstrahlung beams of high energy in combination with dynamic double focused multi-leaf collimation and purging magnets. When using a purging magnet to remove electrons and positrons the target space is limited and unorthodox thin multi-layered targets are needed. A computational technique has therefore been developed to determine the forward yield and the angular distributions of the bremsstrahlung beam as well as the size and location of the effective and the virtual photon point source for arbitrary multi-layer bremsstrahlung targets. The Gaussian approximation of the diffusion equation for the electrons has been used and convolved with the bremsstrahlung production process. For electrons with arbitrary emittance impinging on targets of any multi-layer and atomic number combination, the model is well applicable, at least for energies in the range 1-100 MeV. The intrinsic bremsstrahlung photon profile has been determined accurately by deconvolving the electron multiple scattering process from thin experimental beryllium target profiles. For electron pencil beams incident on a target of high density and atomic number such as tungsten, the size of the effective photon source stays at around a tenth of a millimetre. The effective photon source for low-Z materials such as Be, C and Al is located at depths from 3-7 mm in the target, decreasing with increasing atomic number. The effective photon source at off-axis positions then moves out considerably from the central axis, which should be considered when aligning collimators. For high-Z materials such as tungsten, the location of the effective photon source is at a few tenths of a millimetre deep. The virtual photon point source is located only a few tenths of a millimetre upstream of the effective photon source both for high- and low-Z materials. For 50 MeV electrons incident on multi-layered full range targets the radial

  6. Relativistic self-focusing of intense laser beam in thermal collisionless quantum plasma with ramped density profile

    Directory of Open Access Journals (Sweden)

    S. Zare

    2015-04-01

    Full Text Available Propagation of a Gaussian x-ray laser beam has been analyzed in collisionless thermal quantum plasma with considering a ramped density profile. In this density profile due to the increase in the plasma density, an earlier and stronger self-focusing effect is noticed where the beam width oscillates with higher frequency and less amplitude. Moreover, the effect of the density profile slope and the initial plasma density on the laser propagation has been studied. It is found that, by increasing the initial density and the ramp slope, the laser beam focuses faster with less oscillation amplitude, smaller laser spot size and more oscillations. Furthermore, a comparison is made among the laser self-focusing in thermal quantum plasma, cold quantum plasma and classical plasma. It is realized that the laser self-focusing in the quantum plasma becomes stronger in comparison with the classical regime.

  7. Interaction of the modulated electron beam with inhomogeneous plasma: plasma density profile deformation and langmuir waves excitation

    International Nuclear Information System (INIS)

    Anisimov, I.O.; Kelnyk, O.I.; Soroka, S.V.; Siversky, T.V.

    2005-01-01

    Nonlinear deformation of the initially linear plasma density profile due to the modulated electron beam is studied via computer simulation. In the initial time period the field slaves to the instantaneous profile of the plasma density. Langmuir waves excitation is suppressed by the density profile deformation. The character of the plasma density profile deformation for the late time period depends significantly on the plasma properties. Particularly, for plasma with hot electrons quasi-periodic generation of ion-acoustic pulses takes place in the vicinity of the initial point of plasma resonance

  8. Expedient data mining for nontargeted high-resolution LC-MS profiles of biological samples.

    Science.gov (United States)

    Hnatyshyn, Serhiy; Shipkova, Petia; Sanders, Mark

    2013-05-01

    The application of high-resolution LC-MS metabolomics for drug candidate toxicity screening reflects phenotypic changes of an organism caused by induced chemical interferences. Its success depends not only on the ability to translate the acquired analytical information into biological knowledge, but also on the timely delivery of the results to aid the decision making process in drug discovery and development. Recent improvements in analytical instrumentation have resulted in the ability to acquire extremely information-rich datasets. These new data collection abilities have shifted the bottleneck in the timeline of metabolomic studies to the data analysis step. This paper describes our approach to expedient data analysis of nontargeted high-resolution LC-MS profiles of biological samples. The workflow is illustrated with the example of metabolomics study of time-dependent fasting in male rats. The results from measurement of 220 endogenous metabolites in urine samples illustrate significant biochemical changes induced by fasting. The developed software enables the reporting of relative quantities of annotated components while maintaining practical turnaround times. Each component annotation in the report is validated using both calculated isotopic peaks patterns and experimentally determined retention time data on standards.

  9. Massively parallel digital high resolution melt for rapid and absolutely quantitative sequence profiling

    Science.gov (United States)

    Velez, Daniel Ortiz; Mack, Hannah; Jupe, Julietta; Hawker, Sinead; Kulkarni, Ninad; Hedayatnia, Behnam; Zhang, Yang; Lawrence, Shelley; Fraley, Stephanie I.

    2017-02-01

    In clinical diagnostics and pathogen detection, profiling of complex samples for low-level genotypes represents a significant challenge. Advances in speed, sensitivity, and extent of multiplexing of molecular pathogen detection assays are needed to improve patient care. We report the development of an integrated platform enabling the identification of bacterial pathogen DNA sequences in complex samples in less than four hours. The system incorporates a microfluidic chip and instrumentation to accomplish universal PCR amplification, High Resolution Melting (HRM), and machine learning within 20,000 picoliter scale reactions, simultaneously. Clinically relevant concentrations of bacterial DNA molecules are separated by digitization across 20,000 reactions and amplified with universal primers targeting the bacterial 16S gene. Amplification is followed by HRM sequence fingerprinting in all reactions, simultaneously. The resulting bacteria-specific melt curves are identified by Support Vector Machine learning, and individual pathogen loads are quantified. The platform reduces reaction volumes by 99.995% and achieves a greater than 200-fold increase in dynamic range of detection compared to traditional PCR HRM approaches. Type I and II error rates are reduced by 99% and 100% respectively, compared to intercalating dye-based digital PCR (dPCR) methods. This technology could impact a number of quantitative profiling applications, especially infectious disease diagnostics.

  10. High-resolution moisture profiles from full-waveform probabilistic inversion of TDR signals

    Science.gov (United States)

    Laloy, Eric; Huisman, Johan Alexander; Jacques, Diederik

    2014-11-01

    This study presents an novel Bayesian inversion scheme for high-dimensional undetermined TDR waveform inversion. The methodology quantifies uncertainty in the moisture content distribution, using a Gaussian Markov random field (GMRF) prior as regularization operator. A spatial resolution of 1 cm along a 70-cm long TDR probe is considered for the inferred moisture content. Numerical testing shows that the proposed inversion approach works very well in case of a perfect model and Gaussian measurement errors. Real-world application results are generally satisfying. For a series of TDR measurements made during imbibition and evaporation from a laboratory soil column, the average root-mean-square error (RMSE) between maximum a posteriori (MAP) moisture distribution and reference TDR measurements is 0.04 cm3 cm-3. This RMSE value reduces to less than 0.02 cm3 cm-3 for a field application in a podzol soil. The observed model-data discrepancies are primarily due to model inadequacy, such as our simplified modeling of the bulk soil electrical conductivity profile. Among the important issues that should be addressed in future work are the explicit inference of the soil electrical conductivity profile along with the other sampled variables, the modeling of the temperature-dependence of the coaxial cable properties and the definition of an appropriate statistical model of the residual errors.

  11. Duality based direct resolution of unique profiles using zero concentration region information.

    Science.gov (United States)

    Tavakkoli, Elnaz; Rajkó, Róbert; Abdollahi, Hamid

    2018-07-01

    Self Modeling Curve Resolution (SMCR) is a class of techniques concerned with estimating pure profiles underlying a set of measurements on chemical systems. In general, the estimated profiles are ambiguous (non-unique) except if some special conditions fulfilled. Implementing the adequate information can reduce the so-called rotational ambiguity effectively, and in the most desirable cases lead to the unique solution. Therefore, studies on circumstances resulting in unique solution are of particular importance. The conditions of unique solution can particularly be studied based on duality principle. In bilinear chemical (e.g., spectroscopic) data matrix, there is a natural duality between its row and column vector spaces using minimal constraints (non-negativity of concentrations and absorbances). In this article, the conditions of the unique solution according to duality concept and using zero concentration region information is intended to show. A simulated dataset of three components and an experimental system with synthetic mixtures containing three amino acids tyrosine, phenylalanine and tryptophan are analyzed. It is shown that in the presence of sufficient information, the reliable unique solution is obtained that is valuable in analytical qualification and for quantitative verification analysis. Copyright © 2018 Elsevier B.V. All rights reserved.

  12. High resolution 10Be and 230Th profiles in DSDP site 580

    International Nuclear Information System (INIS)

    Eisenhauer, A.; Mangini, A.; Segl, M.; Beer, J.; Bonani, G.; Suter, M.; Woelfli, W.

    1987-01-01

    10 Be and 230 Th profiles were measured at Site 580 at a depth of 20 m ( 230 Th and 10 Be) and 80 m ( 10 Be), corresponding to 360 ka and 1.5 Ma, respectively, with a resolution of approx. 5000 a. The radiometric sediment accumulation rates of 6.2 cm/ka (±25%) agree well with the average for the last 730 ka (via paleomagnetic stratigraphy). Age corrected concentrations of 10 Be range from 2 to 7x10 9 atoms/g (average 3.5±1). The variations of the 10 Be concentrations can be explained by changes in the sediment supply during different climatic conditions. The maxima and the minima of 10 Be follow the fluctuations of excess 230 Th in the core section during the last 360 ka. Fluxes of both 10 Be and 230 Th exceed production and vary remarkably throughout time suggesting enhanced scavenging by bioproductivity. At the Brunhess-Matuyama boundary we observe a maximum of 10 Be (6.0±0.3x10 9 atoms/g, corresponding to 2.5 σ deviation from the average value). However, the observed large fluctuations of Be-10 throughout the core profile make it difficult to interprete this particular maximum. (orig.)

  13. Eocene Antarctic seasonality inferred from high-resolution stable isotope profiles of fossil bivalves and driftwood

    Science.gov (United States)

    Judd, E. J.; Ivany, L. C.; Miklus, N. M.; Uveges, B. T.; Junium, C. K.

    2017-12-01

    The Eocene Epoch was a time of large-scale global climate change, experiencing both the warmest temperatures of the Cenozoic and the onset of southern hemisphere glaciation. The record of average global temperatures throughout this transition is reasonably well constrained, however considerably less is known about the accompanying changes in seasonality. Seasonally resolved temperature data provide a wealth of information not readily available from mean annual temperature data alone. These data are particularly important in the climatically sensitive high latitudes, as they can elucidate the means by which climate changes and the conditions necessary for the growth of ice sheets. Several recent studies, however, have suggested the potential for monsoonal precipitation regimes in the early-middle Eocene high latitudes, which complicates interpretation of seasonally resolved oxygen isotope records in shallow nearshore marine settings. Seasonal precipitation and runoff could create a brackish, isotopically depleted lens in these environments, depleting summertime δ18Ocarb and thereby inflating the inferred mean and range of isotope-derived temperatures. Here, we assess intra-annual variations in temperature in shallow nearshore Antarctic waters during the middle and late Eocene, inferred from high-resolution oxygen isotope profiles from accretionary bivalves of the La Meseta Formation, Seymour Island, Antarctica. To address concerns related to precipitation and runoff, we also subsample exceptionally preserved fossil driftwood from within the formation and use seasonal differences in δ13Corg values to estimate the ratio of summertime to wintertime precipitation. Late Eocene oxygen isotope profiles exhibit strongly attenuated seasonal amplitudes and more enriched mean annual values in comparison with data from the middle Eocene. Preliminary fossil wood data are not indicative of a strongly seasonal precipitation regime, implying that intra-annual variation in oxygen

  14. Analysis of a Novel Diffractive Scanning-Wire Beam Position Monitor (BPM) for Discriminative Profiling of Electron Vs. X Ray Beams

    International Nuclear Information System (INIS)

    Tatchyn, R.

    2011-01-01

    Recent numerical studies of Free Electron Lasers (FELs) operating in the Self Amplified Spontaneous Emission (SASE) regime indicate a large sensitivity of the gain to the degree of transverse overlap (and associated phase coherence) between the electron and photon beams traveling down the insertion device. Simulations of actual systems imply that accurate detection and correction for this relative loss of overlap, rather than correction for the absolute departure of the electron beam from a fixed axis, is the preferred function of an FEL amplifier's Beam Position Monitor (BPM) and corrector systems. In this note we propose a novel diffractive BPM with the capability of simultaneously detecting and resolving the absolute (and relative) transverse positions and profiles of electron and x-ray beams co-propagating through an undulator. We derive the equations governing the performance of the BPM and examine its predicted performance for the SLAC Linac Coherent Light Source (LCLS), viz., for profiling multi-GeV electron bunches co-propagating with one-to-several-hundred keV x-ray beams. Selected research and development (r and d) tasks for fabricating and testing the proposed BPM are discussed.

  15. UV laser beam profile measurement by means of the photoelectric effect on the wires of a proportional chamber

    International Nuclear Information System (INIS)

    Prokoviev, O.; Seiler, P.G.

    1989-01-01

    A simple technique to measure the profiles of pulsed UV laser beams is described. Irradiating a cathode wire of a proportional chamber with UV laser shots results in signals from the anode wire whose amplitudes are proportional to the UV light intensity. Profile scanning is performed by shifting the chamber across the beam. The chamber can also be used with reversed polarities. This leads to avalanches developing outwardly from the signal wire. In this case we observe a quadratic dependence of the pulse height on the UV light intensity. (orig.)

  16. The Atacama Cosmology Telescope (ACT): Beam Profiles and First SZ Cluster Maps

    Science.gov (United States)

    Hincks, A. D.; Acquaviva, V.; Ade, P. A.; Aguirre, P.; Amiri, M.; Appel, J. W.; Barrientos, L. F.; Battistelli, E. S.; Bond, J. R.; Brown, B.; hide

    2010-01-01

    The Atacama Cosmology Telescope (ACT) is currently observing the cosmic microwave background with arcminute resolution at 148 GHz, 218 GHz, and 277 GHz, In this paper, we present ACT's first results. Data have been analyzed using a maximum-likelihood map-making method which uses B-splines to model and remove the atmospheric signal. It has been used to make high-precision beam maps from which we determine the experiment's window functions, This beam information directly impacts all subsequent analyses of the data. We also used the method to map a sample of galaxy clusters via the Sunyaev-Ze1'dovich (SZ) effect, and show five clusters previously detected with X-ray or SZ observations, We provide integrated Compton-y measurements for each cluster. Of particular interest is our detection of the z = 0.44 component of A3128 and our current non-detection of the low-redshift part, providing strong evidence that the further cluster is more massive as suggested by X-ray measurements. This is a compelling example of the redshift-independent mass selection of the SZ effect.

  17. Inland and Near Shore Water Profiles Derived from the High Altitude Multiple Altimeter Beam Experimental Lidar (MABEL)

    Science.gov (United States)

    Jasinski, Michael F.; Stoll, Jeremy D.; Cook, William B.; Ondrusek, Michael; Stengel, Eric; Brunt, Kelly

    2016-01-01

    The Advanced Topographic Laser Altimeter System (ATLAS) on the Ice, Cloud, and Land Elevation Satellite (ICESat-2) mission is a six beam, low energy, high repetition rate, 532 nm laser transmitter with photon counting detectors. Although designed primarily for detecting height changes in icecaps, sea ice and vegetation, the polar-orbital satellite will observe global surface water during its designed three year life span, including inland water bodies, coasts, and open oceans. In preparation for the mission, an ICESat-2 prototype or the Multiple Altimeter Beam Experimental Lidar (MABEL), was built and flown on high altitude aircraft experiments over a range of inland and near-shore targets. The purpose was to test the ATLAS concept and to provide a database for developing an algorithm that detects along track surface water height and light penetration under a range of atmospheric and water conditions. The current analysis examines the datasets of three MABEL transects observed from 20 km above ground of coastal and inland waters conducted in 2012 and 2013. Transects ranged from about 2 to 12 km in length and included the middle Chesapeake Bay, the near shore Atlantic coast at Virginia Beach, and Lake Mead. Results indicate MABEL's high capability for retrieving surface water height statistics with a mean height precision of approximately 5-7 cm per 100m segment length. Profiles of attenuated subsurface backscatter, characterized using a Signal to Background Ratio written in Log10 base, or LSBR0, were observed over a range of 1.3 to 9.3 meters depending on water clarity and atmospheric background. Results indicate that observable penetration depth, although primarily dependent on water properties, was greatest when solar background rate was low. Near shore bottom reflectance was detected only at the Lake Mead site down to maximum of 10 m under a clear night sky and low turbidity of approximately 1.6 Nephelometric Turbidity Units (NTU). The overall results suggest

  18. Comparison of ONETRAN calculations of electron beam dose profiles with Monte Carlo and experiment

    International Nuclear Information System (INIS)

    Garth, J.C.; Woolf, S.

    1987-01-01

    Electron beam dose profiles have been calculated using a multigroup, discrete ordinates solution of the Spencer-Lewis electron transport equation. This was accomplished by introducing electron transport cross-sections into the ONETRAN code in a simple manner. The authors' purpose is to ''benchmark'' this electron transport model and to demonstrate its accuracy and capabilities over the energy range from 30 keV to 20 MeV. Many of their results are compared with the extensive measurements and TIGER Monte Carlo data. In general the ONETRAN results are smoother, agree with TIGER within the statistical error of the Monte Carlo histograms and require about one tenth the running time of Monte Carlo

  19. A low cost high resolution pattern generator for electron-beam lithography

    International Nuclear Information System (INIS)

    Pennelli, G.; D'Angelo, F.; Piotto, M.; Barillaro, G.; Pellegrini, B.

    2003-01-01

    A simple, very low cost pattern generator for electron-beam lithography is presented. When it is applied to a scanning electron microscope, the system allows a high precision positioning of the beam for lithography of very small structures. Patterns are generated by a suitable software implemented on a personal computer, by using very simple functions, allowing an easy development of new writing strategies for a great adaptability to different user necessities. Hardware solutions, as optocouplers and battery supply, have been implemented for reduction of noise and disturbs on the voltages controlling the positioning of the beam

  20. Naked eye picometer resolution in a Michelson interferometer using conjugated twisted beams.

    Science.gov (United States)

    Emile, Olivier; Emile, Janine

    2017-01-15

    Michelson interferometry is one of the most widely used techniques for accuracy measurements. Its main characteristic feature is to infer a displacement in one of the arms of the interferometer from a phase measurement. Two different twisted beams, also called vortex beams, with opposite twisted rotations in each arm of the interferometer interfere in a daisy flower-like pattern. The number of petals is twice the topological charge. Their position depends on the relative phase of the beams. Naked eye detection of 44 pm displacements is achieved. The sensitivity of such an interferometer together with possible further improvements, and applications are then discussed.

  1. Development of a non-destructive beam-profile monitor based on scintillating fibre planes and SIPMs

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00401943; Ferro-Luzzi, Massimiliano

    CERN's Large Hadron Collider (LHC) is currently the largest particle accelerator in the world. To ensure particle energies at LHC's design values and enable collisions at high energies, the working settings and beam parameters are constantly monitored by the beam instrumentation division. The aim of this thesis is to present a new type of detector to monitor one such beam parameter, the transverse beam profile, and to present the results of an analysis of another beam attribute which reduces the luminosity of collider experiments. Part one of this thesis introduces a detector that uses beam-gas interactions to measure the transverse beam profile. The design of the detector is described in detail and the various components that ensure data quality are introduced. Tests that were conducted to investigate the performance of the detector, like timing and efficiency parameters, are presented as well. The first part is concluded with a summary of the work performed on the detector so far and an outlook of fut...

  2. Studies on the profile measurement of hadron beams by means of residual-gas luminescence and ionization

    International Nuclear Information System (INIS)

    Boehme, Christian Gerhard Heinrich

    2011-01-01

    Modern particle accelerators are applied for a long time no more only in the fundamental physical research but in ever larger extent also in the concrete application for instance in the tumor irradiation or the microprocessor fabrication. The precise knowledge of the beam profile is thereby of great importance for the success. But in intermediate-energy hadron accelerators it hitherto not satisfyingly succeeds to measure the beam profiles not disturbingly. These study presents two not beam-disturbing measuring methods, which are based on the ion beam-residual gas interactions of luminescence and ionization. They were developed for different framework conditions at the JESSICA beam place of the COSY accelerator of the Juelich research center, an advance experiment of the planned European Spallation Source (ESS), as well at the proton synchrotron COSY itself, and the iThemba Laboratory for Accelerator Based Science, Somerset West, South Africa. Thereby the studies consider a large range of possible configuration parameters: Particle momenta from 3 MeV/c to 3 GeV/c, pressures from 1 mbar to 10 -11 mbar and time structures from DC beam to beam bunches of 100 ns length. The experimental arrangement, the application ranges, and the advantages and disadvantages of both methods are explained in this book.

  3. Direct determination of a radiation-damage profile with atomic resolution in ion-irradiated platinum. MSC report No. 5030

    International Nuclear Information System (INIS)

    Pramanik, D.; Seidman, D.N.

    1983-05-01

    The field-ion microscope (FIM) technique has been employed to determine directly a radiation damage profile, with atomic resolution, in a platinum specimen which had been irradiated at 80 0 K with 20-keV Kr + ions to a fluence of 5 x 10 12 cm - 2 . It is shown that the microscopic spatial-vacancy distribution (radiation-damage profile) is directly related to the elastically-deposited-energy profile. The experimentally constructed radiation-damage profile is compared with a theoretical damage profile - calculated employing the TRIM Monte Carlo code - and excellent agreement is obtained between the two, thus demonstrating that it is possible to go directly from a microscopic spatial distribution of vacancies to a continuous radiation-damage profile

  4. Micro-strip Metal Foil Detectors for the Beam Profile Monitoring

    CERN Document Server

    Pugatch, V M; Fedorovitch, O A; Mikhailenko, A V; Prystupa, S V; Pylypchenko, Y

    2005-01-01

    The Micro-strip Metal Foil Detectors (MMFD) designed and used for the Beam Profile Monitoring (BPM) are discussed. Fast particles hitting a metal strip initiate Secondary Electron Emission (SEE) which occurs at 10 - 50 nm surface layers of a strip. The SEE yield is measured by a sensitive Charge Integrator with built-in current-to-frequency converter (1 Hz per 1 fA). The MMFD (deposited onto the 20 μm thick Si-wafer) with 32 Al strips (10 μm wide, 32 μm pitch) has been used for the BPM of the 32 MeV alpha-particle beam at the MPIfK (Heidelberg) Tandem generator for Single-Event-Upset studies of the BEETLE micro-chip. Similar MMFD (0.5 μm thick Ni-strips) with totally removed Si-wafer (by plasma-chemistry, at the working area of 8 x 10 mm2) has been applied for the on-line X-ray BPM at the HASYLAB (DESY). The number of photons (11.3 GeV, mean X-ray energy 18 keV) producing out of a strip a single SEE was evaluated as (1.5 ±0.5)* 104. MMFD has demonstrated stable...

  5. Electron beam and optical depth profiling of quasibulk GaN

    International Nuclear Information System (INIS)

    Chernyak, L.; Osinsky, A.; Nootz, G.; Schulte, A.; Jasinski, J.; Benamara, M.; Liliental-Weber, Z.; Look, D. C.; Molnar, R. J.

    2000-01-01

    Electron beam and optical depth profiling of thick (5.5--64 μm) quasibulk n-type GaN samples, grown by hydride vapor-phase epitaxy, were carried out using electron beam induced current (EBIC), microphotoluminescence (PL), and transmission electron microscopy (TEM). The minority carrier diffusion length, L, was found to increase linearly from 0.25 μm, at a distance of about 5 μm from the GaN/sapphire interface, to 0.63 μm at the GaN surface, for a 36-μm-thick sample. The increase in L was accompanied by a corresponding increase in PL band-to-band radiative transition intensity as a function of distance from the GaN/sapphire interface. We attribute the latter changes in PL intensity and minority carrier diffusion length to a reduced carrier mobility and lifetime at the interface, due to scattering at threading dislocations. The results of EBIC and PL measurements are in good agreement with the values for dislocation density obtained using TEM

  6. Current profile redistribution driven by neutral beam injection in a reversed-field pinch

    Energy Technology Data Exchange (ETDEWEB)

    Parke, E. [Department of Physics and Astronomy, University of California Los Angeles 475 Portola Plaza, Los Angeles, California 90095 (United States); Department of Physics, University of Wisconsin-Madison 1150 University Ave., Madison, Wisconsin 53706 (United States); Anderson, J. K.; Den Hartog, D. J. [Department of Physics, University of Wisconsin-Madison 1150 University Ave., Madison, Wisconsin 53706 (United States); Brower, D. L.; Ding, W. X.; Lin, L. [Department of Physics and Astronomy, University of California Los Angeles 475 Portola Plaza, Los Angeles, California 90095 (United States); Johnson, C. A. [Department of Physics, University of Wisconsin-Madison 1150 University Ave., Madison, Wisconsin 53706 (United States); Department of Physics, Auburn University 206 Allison Laboratory, Auburn, Alabama 36849 (United States)

    2016-05-15

    Neutral beam injection in reversed-field pinch (RFP) plasmas on the Madison Symmetric Torus [Dexter et al., Fusion Sci. Technol. 19, 131 (1991)] drives current redistribution with increased on-axis current density but negligible net current drive. Internal fluctuations correlated with tearing modes are observed on multiple diagnostics; the behavior of tearing mode correlated structures is consistent with flattening of the safety factor profile. The first application of a parametrized model for island flattening to temperature fluctuations in an RFP allows inferrence of rational surface locations for multiple tearing modes. The m = 1, n = 6 mode is observed to shift inward by 1.1 ± 0.6 cm with neutral beam injection. Tearing mode rational surface measurements provide a strong constraint for equilibrium reconstruction, with an estimated reduction of q{sub 0} by 5% and an increase in on-axis current density of 8% ± 5%. The inferred on-axis current drive is consistent with estimates of fast ion density using TRANSP [Goldston et al., J. Comput. Phys. 43, 61 (1981)].

  7. High resolution beam line of the U400M cyclotron and RIB accumulation and cooling in the K4 storage ring

    International Nuclear Information System (INIS)

    Rodin, A.M.; Sidorchuk, S.I.; Stepantsov, S.V.

    1996-01-01

    The high resolution beam line ACCULINNA put into operation on a primary beam line of the JINR U400M cyclotron is discussed in the framework of the TREBLE project. The capability of the beam line for producing radioactive ion beams is demonstrated by means of nuclear fragmentation of the primary 14 N beam, with the energy of 51 MeV · A, on the 170 mg/cm 2 carbon target. Characteristics of the obtained 6 He, 8 He and 8 B radioactive beams are presented. A scheme of accumulation and cooling on the orbit of the storage ring K4 is proposed for a low intensity radioactive beam obtained from this beam line. 8 refs., 6 figs., 1 tab

  8. iCycle: Integrated, multicriterial beam angle, and profile optimization for generation of coplanar and noncoplanar IMRT plans

    International Nuclear Information System (INIS)

    Breedveld, Sebastiaan; Storchi, Pascal R. M.; Voet, Peter W. J.; Heijmen, Ben J. M.

    2012-01-01

    Purpose: To introduce iCycle, a novel algorithm for integrated, multicriterial optimization of beam angles, and intensity modulated radiotherapy (IMRT) profiles. Methods: A multicriterial plan optimization with iCycle is based on a prescription called wish-list, containing hard constraints and objectives with ascribed priorities. Priorities are ordinal parameters used for relative importance ranking of the objectives. The higher an objective priority is, the higher the probability that the corresponding objective will be met. Beam directions are selected from an input set of candidate directions. Input sets can be restricted, e.g., to allow only generation of coplanar plans, or to avoid collisions between patient/couch and the gantry in a noncoplanar setup. Obtaining clinically feasible calculation times was an important design criterium for development of iCycle. This could be realized by sequentially adding beams to the treatment plan in an iterative procedure. Each iteration loop starts with selection of the optimal direction to be added. Then, a Pareto-optimal IMRT plan is generated for the (fixed) beam setup that includes all so far selected directions, using a previously published algorithm for multicriterial optimization of fluence profiles for a fixed beam arrangement Breedveld et al.[Phys. Med. Biol. 54, 7199-7209 (2009)]. To select the next direction, each not yet selected candidate direction is temporarily added to the plan and an optimization problem, derived from the Lagrangian obtained from the just performed optimization for establishing the Pareto-optimal plan, is solved. For each patient, a single one-beam, two-beam, three-beam, etc. Pareto-optimal plan is generated until addition of beams does no longer result in significant plan quality improvement. Plan generation with iCycle is fully automated. Results: Performance and characteristics of iCycle are demonstrated by generating plans for a maxillary sinus case, a cervical cancer patient, and a

  9. SU-E-T-149: Electron Beam Profile Differences Between Elekta MLCi2 and Elekta Agility Treatment Heads

    Energy Technology Data Exchange (ETDEWEB)

    Wu, C [Sutter Medical Foundation, Roseville, CA 95661 (United States); Hatcher, C [Sutter Shared Services S3, Sacramento, CA (United States)

    2014-06-01

    Purpose: To report and investigate observed differences in electron beam profiles at various energies/applicators between Elekta MLCi2 and Agility treatment head on Elekta Infinity LINAC Methods: When we upgraded from MLCi2 to Agility on one of our Elekta Infinity LINAC's, electron beam PDDs and profiles were acquired for comparison purpose. All clinical electron energies (6/9/12/15/12/18 MeV) and electron applicators (6/10/14/20/25 square) were included in measurement. PDDs were acquired at 100 SSD in water (PTW MP3 water tank) with a plane-parallel ion chamber (PTW Roos). X and Y Profiles were acquired using IC Profiler (Sun Nuclear Corp.) at 1cm and maximum PDD depths (water equivalent). Results: All PDD curves match very well between MLCi2 and Agility treatment head. However, some significant differences on electron profiles were found. On Agility, even after increasing the default auto-tracking offset values for backup diaphragms in Y and MLC in X by 2.8 cm (the maximum allowed change is 3.0 cm), electron profiles still have rounder shoulders comparing to corresponding MLCi2 profiles. This difference is significantly more pronounced at larger applicators (20 and 25 square), for all electron energies. Conclusion: The significant design change between MLCi2 and Agility beam limiting device seems to affect exit electron beam profiles. In IEC1217 X direction, the main change on Agility is the removal of the original MLCi2 X backup diaphragms and replacing it with MLC leaves; In Y direction, the main change is the radius and materials on Y backup diaphragms.

  10. ASTC-MIMO-TOPS Mode with Digital Beam-Forming in Elevation for High-Resolution Wide-Swath Imaging

    Directory of Open Access Journals (Sweden)

    Pingping Huang

    2015-03-01

    Full Text Available Future spaceborne synthetic aperture radar (SAR missions require complete and frequent coverage of the earth with a high resolution. Terrain Observation by Progressive Scans (TOPS is a novel wide swath mode but has impaired azimuth resolution. In this paper, an innovative extended TOPS mode named Alamouti Space-time Coding multiple-input multiple-output TOPS (ASTC-MIMO-TOPS mode combined with digital beam-forming (DBF in elevation and multi-aperture SAR signal reconstruction in azimuth is proposed. This innovative mode achieves wide-swath coverage with a high geometric resolution and also overcomes major drawbacks in conventional MIMO SAR systems. The data processing scheme of this imaging scheme is presented in detail. The designed system example of the proposed ASTC-MIMO-TOPS mode, which has the imaging capacity of a 400 km wide swath with an azimuth resolution of 3 m, is given. Its system performance analysis results and simulated imaging results on point targets demonstrate the potential of the proposed novel spaceborne SAR mode for high-resolution wide-swath (HRWS imaging.

  11. Two-beam ultrabroadband coherent anti-Stokes Raman spectroscopy for high resolution gas-phase multiplex imaging

    Energy Technology Data Exchange (ETDEWEB)

    Bohlin, Alexis; Kliewer, Christopher J., E-mail: cjkliew@sandia.gov [Combustion Research Facility, Sandia National Laboratories, Livermore, California 94550 (United States)

    2014-01-20

    We propose and develop a method for wideband coherent anti-Stokes Raman spectroscopy (CARS) in the gas phase and demonstrate the single-shot measurement of N{sub 2}, H{sub 2}, CO{sub 2}, O{sub 2}, and CH{sub 4}. Pure-rotational and vibrational O-, Q-, and S- branch spectra are collected simultaneously, with high spectral and spatial resolution, and within a single-laser-shot. The relative intensity of the rotational and vibrational signals can be tuned arbitrarily using polarization techniques. The ultrashort 7 fs pump and Stokes pulses are automatically overlapped temporally and spatially using a two-beam CARS technique, and the crossed probe beam allows for excellent spatial sectioning of the probed location.

  12. Two-beam ultrabroadband coherent anti-Stokes Raman spectroscopy for high resolution gas-phase multiplex imaging

    International Nuclear Information System (INIS)

    Bohlin, Alexis; Kliewer, Christopher J.

    2014-01-01

    We propose and develop a method for wideband coherent anti-Stokes Raman spectroscopy (CARS) in the gas phase and demonstrate the single-shot measurement of N 2 , H 2 , CO 2 , O 2 , and CH 4 . Pure-rotational and vibrational O-, Q-, and S- branch spectra are collected simultaneously, with high spectral and spatial resolution, and within a single-laser-shot. The relative intensity of the rotational and vibrational signals can be tuned arbitrarily using polarization techniques. The ultrashort 7 fs pump and Stokes pulses are automatically overlapped temporally and spatially using a two-beam CARS technique, and the crossed probe beam allows for excellent spatial sectioning of the probed location

  13. Vertical profiles of BC direct radiative effect over Italy: high vertical resolution data and atmospheric feedbacks

    Science.gov (United States)

    Močnik, Griša; Ferrero, Luca; Castelli, Mariapina; Ferrini, Barbara S.; Moscatelli, Marco; Grazia Perrone, Maria; Sangiorgi, Giorgia; Rovelli, Grazia; D'Angelo, Luca; Moroni, Beatrice; Scardazza, Francesco; Bolzacchini, Ezio; Petitta, Marcello; Cappelletti, David

    2016-04-01

    Black carbon (BC), and its vertical distribution, affects the climate. Global measurements of BC vertical profiles are lacking to support climate change research. To fill this gap, a campaign was conducted over three Italian basin valleys, Terni Valley (Appennines), Po Valley and Passiria Valley (Alps), to characterize the impact of BC on the radiative budget under similar orographic conditions. 120 vertical profiles were measured in winter 2010. The BC vertical profiles, together with aerosol size distribution, aerosol chemistry and meteorological parameters, have been determined using a tethered balloon-based platform equipped with: a micro-Aethalometer AE51 (Magee Scientific), a 1.107 Grimm OPC (0.25-32 μm, 31 size classes), a cascade impactor (Siuotas SKC), and a meteorological station (LSI-Lastem). The aerosol chemical composition was determined from collected PM2.5 samples. The aerosol absorption along the vertical profiles was measured and optical properties calculated using the Mie theory applied to the aerosol size distribution. The aerosol optical properties were validated with AERONET data and then used as inputs to the radiative transfer model libRadtran. Vertical profiles of the aerosol direct radiative effect, the related atmospheric absorption and the heating rate were calculated. Vertical profile measurements revealed some common behaviors over the studied basin valleys. From below the mixing height to above it, a marked concentration drop was found for both BC (from -48.4±5.3% up to -69.1±5.5%) and aerosol number concentration (from -23.9±4.3% up to -46.5±7.3%). These features reflected on the optical properties of the aerosol. Absorption and scattering coefficients decreased from below the MH to above it (babs from -47.6±2.5% up to -71.3±3.0% and bsca from -23.5±0.8% up to -61.2±3.1%, respectively). Consequently, the Single Scattering Albedo increased above the MH (from +4.9±2.2% to +7.4±1.0%). The highest aerosol absorption was

  14. Non-targeted glycosidic profiling of international wines using neutral loss-high resolution mass spectrometry.

    Science.gov (United States)

    Barnaba, C; Dellacassa, E; Nicolini, G; Nardin, T; Serra, M; Larcher, R

    2018-07-06

    Many metabolites naturally occur as glycosides, since sugar moieties can be crucial for their biological activity and increase their water solubility. In the plant kingdom they may occur as glycosides or sugar esters, depending on precursor chemical structure, and in wine they have traditionally attracted attention due to their organoleptic properties, such as astringency and bitterness, and because they affect the colour and aroma of wines. A new approach directed at detailed description of glycosides in a large selection of monovarietal wines (8 samples each of Pinot Blanc, Muller Thurgau, Riesling, Traminer, Merlot, Pinot Noir and Cabernet Sauvignon) was developed by combining high performance liquid chromatography with high resolution tandem mass spectrometry. Analytical separation was performed on an Accucore™ Polar Premium LC column, while mass analysis was performed in negative ion mode with an non-targeted screening approach, using a Full MS/AIF/NL dd-MS 2 experiment at a resolving power of 140,000 FWHM. Over 280 glycoside-like compounds were detected, of which 133 (including low-molecular weight phenols, flavonoids and monoterpenols) were tentatively identified in the form of pentose (6), deoxyhexose (17), hexose (73), hexose-pentose (16), hexose-deoxyhexose (7), dihexose (5) and hexose ester (9) derivatives. It was not possible to univocally define the corresponding chemical structure for the remaining 149 glycosides. Non-parametric statistical analysis showed it was possible to well characterise the glycosylated profile of all red and Traminer wines, while the identified glycosides were almost entirely lacking in Pinot Blanc, Riesling and Muller Thurgau wines. Also Tukey's Honestly Significant Difference test (p wines from each other according to their glycosylated profile. Copyright © 2018 Elsevier B.V. All rights reserved.

  15. The profile of the electron beam in the PTB synchrotron, and its influence on radiometric measurements with synchrotron radiation

    International Nuclear Information System (INIS)

    Kaase, H.

    1976-01-01

    A simple method is described to determine the beam profile in an electron synchrotron; the measured results are compared with calculated values. Moreover, the influence of synchrotron- and betatron-oscillations on synchrotron radiation measurements is discussed, and a method is given to correct this. (orig.) [de

  16. In-beam measurement of the position resolution of a highly segmented coaxial germanium detector

    International Nuclear Information System (INIS)

    Descovich, M.; Lee, I.Y.; Fallon, P.; Cromaz, M.; Macchiavelli, A.O.; Radford, D.C.; Vetter, K.; Clark, R.M.; Deleplanque, M.A.; Stephens, F.S.; Ward, D.

    2005-01-01

    The position resolution of a highly segmented coaxial germanium detector was determined by analyzing the 2055keV γ-ray transition of Zr90 excited in a fusion-evaporation reaction. The high velocity of the Zr90 nuclei imparted large Doppler shifts. Digital analysis of the detector signals recovered the energy and position of individual γ-ray interactions. The location of the first interaction in the crystal was used to correct the Doppler energy shift. Comparison of the measured energy resolution with simulations implied a position resolution (root mean square) of 2mm in three-dimensions

  17. Targeted metabolite profile of food bioactive compounds by Orbitrap high resolution mass spectrometry: The 'FancyTiles' approach

    NARCIS (Netherlands)

    Troise, A.D.; Ferracane, R.; Palermo, M.; Fogliano, V.

    2014-01-01

    In this paper a new targeted metabolic profile approach using Orbitrap high resolution mass spectrometry was described. For each foodmatrix various classes of bioactive compounds and some specificmetabolites of interest were selected on the basis of the existing knowledge creating an easy-to-read

  18. High time resolution beam-based measurement of the rf-to-laser jitter in a photocathode rf gun

    Directory of Open Access Journals (Sweden)

    Zhen Zhang

    2014-03-01

    Full Text Available Characterizing the rf-to-laser jitter in the photocathode rf gun and its possible origins is important for improving the synchronization and beam quality of the linac based on the photocathode rf gun. A new method based on the rf compression effect in the photocathode rf gun is proposed to measure the rf-to-laser jitter in the gun. By taking advantage of the correlation between the rf compression and the laser injection phase, the error caused by the jitter of the accelerating field in the gun is minimized and thus 10 fs time resolution is expected. Experimental demonstration at the Tsinghua Thomson scattering x-ray source with a time resolution better than 35 fs is reported in this paper. The experimental results are successfully used to obtain information on the possible cause of the jitter and the accompanying drifts.

  19. Attention-Based Recurrent Temporal Restricted Boltzmann Machine for Radar High Resolution Range Profile Sequence Recognition

    Directory of Open Access Journals (Sweden)

    Yifan Zhang

    2018-05-01

    Full Text Available The High Resolution Range Profile (HRRP recognition has attracted great concern in the field of Radar Automatic Target Recognition (RATR. However, traditional HRRP recognition methods failed to model high dimensional sequential data efficiently and have a poor anti-noise ability. To deal with these problems, a novel stochastic neural network model named Attention-based Recurrent Temporal Restricted Boltzmann Machine (ARTRBM is proposed in this paper. RTRBM is utilized to extract discriminative features and the attention mechanism is adopted to select major features. RTRBM is efficient to model high dimensional HRRP sequences because it can extract the information of temporal and spatial correlation between adjacent HRRPs. The attention mechanism is used in sequential data recognition tasks including machine translation and relation classification, which makes the model pay more attention to the major features of recognition. Therefore, the combination of RTRBM and the attention mechanism makes our model effective for extracting more internal related features and choose the important parts of the extracted features. Additionally, the model performs well with the noise corrupted HRRP data. Experimental results on the Moving and Stationary Target Acquisition and Recognition (MSTAR dataset show that our proposed model outperforms other traditional methods, which indicates that ARTRBM extracts, selects, and utilizes the correlation information between adjacent HRRPs effectively and is suitable for high dimensional data or noise corrupted data.

  20. Resolution of Chlamydia trachomatis Infection Is Associated with a Distinct T Cell Response Profile.

    Science.gov (United States)

    Picard, Michele D; Bodmer, Jean-Luc; Gierahn, Todd M; Lee, Alexander; Price, Jessica; Cohane, Kenya; Clemens, Veronica; DeVault, Victoria L; Gurok, Galina; Kohberger, Robert; Higgins, Darren E; Siber, George R; Flechtner, Jessica Baker; Geisler, William M

    2015-11-01

    Chlamydia trachomatis is the causative agent of the most frequently reported bacterial sexually transmitted infection, the total burden of which is underestimated due to the asymptomatic nature of the infection. Untreated C. trachomatis infections can cause significant morbidities, including pelvic inflammatory disease and tubal factor infertility (TFI). The human immune response against C. trachomatis, an obligate intracellular bacterium, is poorly characterized but is thought to rely on cell-mediated immunity, with CD4(+) and CD8(+) T cells implicated in protection. In this report, we present immune profiling data of subjects enrolled in a multicenter study of C. trachomatis genital infection. CD4(+) and CD8(+) T cells from subjects grouped into disease-specific cohorts were screened using a C. trachomatis proteomic library to identify the antigen specificities of recall T cell responses after natural exposure by measuring interferon gamma (IFN-γ) levels. We identified specific T cell responses associated with the resolution of infection, including unique antigens identified in subjects who spontaneously cleared infection and different antigens associated with C. trachomatis-related sequelae, such as TFI. These data suggest that novel and unique C. trachomatis T cell antigens identified in individuals with effective immune responses can be considered as targets for vaccine development, and by excluding antigens associated with deleterious sequelae, immune-mediated pathologies may be circumvented. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  1. Metabolite profiling of carbamazepine and ibuprofen in Solea senegalensis bile using high-resolution mass spectrometry.

    Science.gov (United States)

    Aceña, Jaume; Pérez, Sandra; Eichhorn, Peter; Solé, Montserrat; Barceló, Damià

    2017-09-01

    The widespread occurrence of pharmaceuticals in the aquatic environment has raised concerns about potential adverse effects on exposed wildlife. Very little is currently known on exposure levels and clearance mechanisms of drugs in marine fish. Within this context, our research was focused on the identification of main metabolic reactions, generated metabolites, and caused effects after exposure of fish to carbamazepine (CBZ) and ibuprofen (IBU). To this end, juveniles of Solea senegalensis acclimated to two temperature regimes of 15 and 20 °C for 60 days received a single intraperitoneal dose of these drugs. A control group was administered the vehicle (sunflower oil). Bile samples were analyzed by ultra-high-performance liquid chromatography-high-resolution mass spectrometry on a Q Exactive (Orbitrap) system, allowing to propose plausible identities for 11 metabolites of CBZ and 13 metabolites of IBU in fish bile. In case of CBZ metabolites originated from aromatic and benzylic hydroxylation, epoxidation, and ensuing O-glucuronidation, O-methylation of a catechol-like metabolite was also postulated. Ibuprofen, in turn, formed multiple hydroxyl metabolites, O-glucuronides, and (hydroxyl)-acyl glucuronides, in addition to several taurine conjugates. Enzymatic responses after drug exposures revealed a water temperature-dependent induction of microsomal carboxylesterases. The metabolite profiling in fish bile provides an important tool for pharmaceutical exposure assessment. Graphical abstract Studies of metabolism of carbamazepine and ibuprofen in fish.

  2. High-Resolution Microbiome Profiling for Detection and Tracking of Salmonella enterica

    Directory of Open Access Journals (Sweden)

    Christopher J. Grim

    2017-08-01

    Full Text Available 16S rRNA community profiling continues to be a useful tool to study microbiome composition and dynamics, in part due to advances in next generation sequencing technology that translate into reductions in cost. Reliable taxonomic identification to the species-level, however, remains difficult, especially for short-read sequencing platforms, due to incomplete coverage of the 16S rRNA gene. This is especially true for Salmonella enterica, which is often found as a low abundant member of the microbial community, and is often found in combination with several other closely related enteric species. Here, we report on the evaluation and application of Resphera Insight, an ultra-high resolution taxonomic assignment algorithm for 16S rRNA sequences to the species level. The analytical pipeline achieved 99.7% sensitivity to correctly identify S. enterica from WGS datasets extracted from the FDA GenomeTrakr Bioproject, while demonstrating 99.9% specificity over other Enterobacteriaceae members. From low-diversity and low-complexity samples, namely ice cream, the algorithm achieved 100% specificity and sensitivity for Salmonella detection. As demonstrated using cilantro and chili powder, for highly complex and diverse samples, especially those that contain closely related species, the detection threshold will likely have to be adjusted higher to account for misidentifications. We also demonstrate the utility of this approach to detect Salmonella in the clinical setting, in this case, bloodborne infections.

  3. Development of high resolution vacuum ultraviolet beam line at Indus-1 synchrotron source

    International Nuclear Information System (INIS)

    Shukla, R.P.; Das, N.C.; Udupa, D.V.; Saraswathy, P.; Sunanda, K.; Jha, S.N.; Shastri, Aparna; Singh, Paramjeet; Mallick, Manika; Mishra, A.P.; Sahoo, N.K.; Sinha, A.K.; Bhatt, S.; Sahni, V.C.

    2005-07-01

    High resolution vacuum ultraviolet beamline at Indus-1 450 MeV synchrotron source has been developed for carrying out absorption spectral studies of atoms and molecules. The beamline consists of three major parts i.e. a focusing optical system, an absorption cell and a high resolution 6.65 m vacuum ultraviolet spectrometer in Eagle mount. The wavelength range of the spectrometer is from 700 A to 2000 A and the resolution of the spectrometer is 0.01 A. Using the synchrotron source Indus-1, the absorption spectra of oxygen, ammonia and carbon disulphide have been recorded at the wavelength band of 1750 A, 1881 A and 3100 A respectively. Details of different aspects of design and development of the high resolution VUV beamline are described in this report. (author)

  4. Frequency Characteristics of Surface Wave Generated by Single-Line Pulsed Laser Beam with Two Kinds of Spatial Energy Profile Models: Gaussian and Square-Like

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Ho Geon; Kim, Myung Hwan; Choi, Sung Ho; Kim, Chung Seok; Jhang, Kyung Young [Hanyang University, Seoul (Korea, Republic of)

    2012-08-15

    Using a single-line pulsed laser beam is well known as a useful noncontact method to generate a directional surface acoustic wave. In this method, different laser beam energy profiles produce different waveforms and frequency characteristics. In this paper, we considered two typical kinds of laser beam energy profiles, Gaussian and square-like, to find out a difference in the frequency characteristics. To achieve this, mathematical models were proposed first for Gaussian laser beam profile and square-like respectively, both of which depended on the laser beam width. To verify the theoretical models, experimental setups with a cylindrical lens and a line-slit mask were respectively designed to produce a line laser beam with Gaussian spatial energy profile and square-like. The frequency responses of the theoretical models showed good agreement with experimental results in terms of the existence of harmonic frequency components and the shift of the first peak frequencies to low.

  5. Ultrahigh resolution focused electron beam induced processing: the effect of substrate thickness

    DEFF Research Database (Denmark)

    van Dorp, Willem F; Lazic, Ivan; Beyer, André

    2011-01-01

    It is often suggested that the growth in focused electron beam induced processing (FEBIP) is caused not only by primary electrons, but also (and even predominantly) by secondary electrons (SEs). If that is true, the growth rate for FEBIP can be changed by modifying the SE yield. Results from our ...

  6. High resolution magnetic force microscopy using focused ion beam modified tips

    NARCIS (Netherlands)

    Phillips, G.N.; Siekman, Martin Herman; Abelmann, Leon; Lodder, J.C.

    2002-01-01

    Atomic force microscope tips coated by the thermal evaporation of a magnetic 30 nm thick Co film have been modified by focused ion beam milling with Ga+ ions to produce tips suitable for magnetic force microscopy. Such tips possess a planar magnetic element with high magnetic shape anisotropy, an

  7. Inland and Near-Shore Water Profiles Derived from the High-Altitude Multiple Altimeter Beam Experimental Lidar (MABEL)

    Science.gov (United States)

    Jasinski, Michael F.; Stoll, Jeremy D.; Cook, William B.; Ondrusek, Michael; Stengel, Eric; Brunt, Kelly

    2016-01-01

    The Advanced Topographic Laser Altimeter System (ATLAS) on the Ice, Cloud, and Land Elevation Satellite (ICESat-2) mission is a six beam, low energy, high repetition rate, 532-nanometer laser transmitter with photon counting detectors. Although designed primarily for detecting height changes in ice caps, sea ice, and vegetation, the polar-orbiting satellite will observe global surface water during its designed three-year life span, including inland waterbodies, coasts, and open oceans. In preparation for the mission, an ICESat-2 prototype, the Multiple Altimeter Beam Experimental Lidar (MABEL), was built and flown on high-altitude aircraft experiments over a range of inland and near-shore targets. The purpose was to test the ATLAS concept and to provide a database for developing an algorithm that detects along track surface water height and light penetration under a range of atmospheric and water conditions. The current analysis examines the data sets of three MABEL transects observed from 20 kilometers above ground of coastal and inland waters conducted in 2012 and 2013. Transects ranged from about 2 to 12 kilometers in length and included the middle Chesapeake Bay, the near-shore Atlantic coast at Virginia Beach, and Lake Mead. Results indicate MABEL's high capability for retrieving surface water height statistics with a mean height precision ofapproximately 5-7 centimeters per 100-meter segment length. Profiles of attenuated subsurface backscatter, characterized using a Signal to Background Ratio written in Log10 base, or LSBR (sub 0), were observed over a range of 1.3 to 9.3 meters, depending on water clarity and atmospheric background. Results indicate that observable penetration depth, although primarily dependent on water properties, was greatest when the solar background rate was low. Near-shore bottom reflectance was detected only at the Lake Mead site down to a maximum of 10 meters under a clear night sky and low turbidity of approximately 1

  8. Deceleration of probe beam by stage bias potential improves resolution of serial block-face scanning electron microscopic images.

    Science.gov (United States)

    Bouwer, James C; Deerinck, Thomas J; Bushong, Eric; Astakhov, Vadim; Ramachandra, Ranjan; Peltier, Steven T; Ellisman, Mark H

    2017-01-01

    Serial block-face scanning electron microscopy (SBEM) is quickly becoming an important imaging tool to explore three-dimensional biological structure across spatial scales. At probe-beam-electron energies of 2.0 keV or lower, the axial resolution should improve, because there is less primary electron penetration into the block face. More specifically, at these lower energies, the interaction volume is much smaller, and therefore, surface detail is more highly resolved. However, the backscattered electron yield for metal contrast agents and the backscattered electron detector sensitivity are both sub-optimal at these lower energies, thus negating the gain in axial resolution. We found that the application of a negative voltage (reversal potential) applied to a modified SBEM stage creates a tunable electric field at the sample. This field can be used to decrease the probe-beam-landing energy and, at the same time, alter the trajectory of the signal to increase the signal collected by the detector. With decelerated low landing-energy electrons, we observed that the probe-beam-electron-penetration depth was reduced to less than 30 nm in epoxy-embedded biological specimens. Concurrently, a large increase in recorded signal occurred due to the re-acceleration of BSEs in the bias field towards the objective pole piece where the detector is located. By tuning the bias field, we were able to manipulate the trajectories of the  primary and secondary electrons, enabling the spatial discrimination of these signals using an advanced ring-type BSE detector configuration or a standard monolithic BSE detector coupled with a blocking aperture.

  9. Optical Sideband Generation: a Longitudinal Electron Beam Diagnostic Beyond the Laser Bandwidth Resolution Limit

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence Berkeley National Laboratory; Tilborg, J. van; Matlis, N. H.; Plateau, G. R.; Leemans, W. P.

    2010-06-01

    Electro-optic sampling (EOS) is widely used as a technique to measure THz-domain electric field pulses such asthe self-fields of femtosecond electron beams. We present an EOS-based approach for single-shot spectral measurement that excels in simplicity (compatible with fiber integration) and bandwidth coverage (overcomes the laser bandwidth limitation), allowing few-fs electron beams or single-cycle THz pulses to be characterized with conventional picosecond probes. It is shown that the EOS-induced optical sidebands on the narrow-bandwidth optical probe are spectrally-shifted replicas of the THz pulse. An experimental demonstration on a 0-3 THz source is presented.

  10. Testing of Track Point Resolution of Gas Electron Multiplier with Pion Beam at CERN SPS

    CERN Document Server

    Adak, R P; Das, S; Dubey, A K; Ganti, M S; Saini, J; Singaraju, R

    2015-01-01

    A muon detection system using segmented and instrumented absorber has been designed for high-energy heavy-ion collision experiments to be held at GSI, Darmstadt, Germany. The muon detector system is mounted downstream of a Silicon Tracking System. The reconstructed tracks from the STS are to be matched to the hits in the GEM detector. For reconstructing track in the GEM Detector, track point resolution is an important issue. We report her first time the track point resolution of the GEM detector.

  11. Applications of focused MeV light ion beams for high resolution channeling contrast imaging

    Energy Technology Data Exchange (ETDEWEB)

    Jamieson, D N; Breese, M B.H.; Prawer, S; Dooley, S P; Allen, M G; Bettiol, A A; Saint, A [Melbourne Univ., Parkville, VIC (Australia). School of Physics; Ryan, C G [Commonwealth Scientific and Industrial Research Organisation (CSIRO), North Ryde, NSW (Australia). Div. of Exploration Geoscience

    1994-12-31

    The technique of Nuclear Microscopy, utilizing a focused ion probe of typically MeV H{sup +} or He{sup +} ions, can produce images where the contrast depends on typical Ion Beam Analysis (lBA) processes. The probe forming lens system usually utilizes strong focusing, precision magnetic quadrupole lenses and the probe is scanned over the target to produce images. Originally, this imaging technique was developed to utilize backscattered particles with incident beam currents typically of a few nA, and the technique became known as Channeling Contrast Microscopy (CCM). Recently, the technique has been developed further to utilize the forward scattering of ions incident along a major crystal axis in thin crystals. This technique is known as Channeling Scanning Transmission Ion Microscopy (CSTIM). Since nearly all incident ions are detected, CSTIM is highly efficient and very low beam currents are sufficient for imaging, typically as low as a few fA. This allows probes as small as 50 nm to be used. In this paper we briefly review the recent applications of these emerging techniques to a variety of single crystal materials (authors). 13 refs., 5 figs.

  12. Applications of focused MeV light ion beams for high resolution channeling contrast imaging

    Energy Technology Data Exchange (ETDEWEB)

    Jamieson, D.N.; Breese, M.B.H.; Prawer, S.; Dooley, S.P.; Allen, M.G.; Bettiol, A.A.; Saint, A. [Melbourne Univ., Parkville, VIC (Australia). School of Physics; Ryan, C.G. [Commonwealth Scientific and Industrial Research Organisation (CSIRO), North Ryde, NSW (Australia). Div. of Exploration Geoscience

    1993-12-31

    The technique of Nuclear Microscopy, utilizing a focused ion probe of typically MeV H{sup +} or He{sup +} ions, can produce images where the contrast depends on typical Ion Beam Analysis (lBA) processes. The probe forming lens system usually utilizes strong focusing, precision magnetic quadrupole lenses and the probe is scanned over the target to produce images. Originally, this imaging technique was developed to utilize backscattered particles with incident beam currents typically of a few nA, and the technique became known as Channeling Contrast Microscopy (CCM). Recently, the technique has been developed further to utilize the forward scattering of ions incident along a major crystal axis in thin crystals. This technique is known as Channeling Scanning Transmission Ion Microscopy (CSTIM). Since nearly all incident ions are detected, CSTIM is highly efficient and very low beam currents are sufficient for imaging, typically as low as a few fA. This allows probes as small as 50 nm to be used. In this paper we briefly review the recent applications of these emerging techniques to a variety of single crystal materials (authors). 13 refs., 5 figs.

  13. Charge and velocity resolution of Cerenkov counters in a beam of accelerated heavy nuclei

    International Nuclear Information System (INIS)

    Cantin, M.; Goret, P.; Jorrand, J.; Jouan, R.; Juliusson, E.; Koch, L.; Maubras, Y.; Mestreau, P.; Petrou, N.; Rio, Y.; Soutoul, A.; Cawood, P.; Linney, A.

    1975-01-01

    The response of various Cerenkov radiators to oxygen and nitrogen nuclei with energies ranging between 2.1GeV/n and 300MeV/n is presented. The velocity and charge resolutions are analyzed in relation to the possible use of these counters for chemical and isotopic analysis of the primary cosmic ray nuclei [fr

  14. Effects of the intensity levels and beam map resolutions on static IMRT plans

    International Nuclear Information System (INIS)

    Sun Xuepeng; Xia Ping; Yu Naichang

    2004-01-01

    In this study we focus on how the intensity level and multileaf collimator (MLC) resolution affect the quality of IMRT plans using the static MLC delivery technique. The planning process is based on a least-square dose-based quadratic function and uses a simulated annealing algorithm to sample the discrete variables. Three clinical cases are studied empirically: a medulloblastoma, a prostate, and an oropharyngeal carcinoma. The intensity levels used are 3, 5, 10, 20, and continuous; the map resolution varies from 0.15-1.5 cm, with the leaf width equal to the step size. The influence of these two parameters are studied by comparing the cost value and the cost of delivery time from a trade-off point of view. An 'efficient frontier' is drawn by connecting the plans with the lowest cost value at any given resolutions. For each case, a practical delivery region is defined by doubling the delivery time needed at a normal setting (five levels, 1.0 cm). Within this region, the 'efficient frontier' demonstrates that the plans with five intensity levels are the most efficient comparing with plans with higher levels. This is a confirmation of the conclusion from Keller-Reichenbecher et al. [Int. J. Radiat. Oncol., Biol., Phys. 45, 1315-1324 (1999)]. It indicates that to further improve the plan quality with the minimal cost of extra delivery time, the most economical way is to improve the resolution rather than using higher intensity levels

  15. Influence of the Laser Spot Size, Focal Beam Profile, and Tissue Type on the Lipid Signals Obtained by MALDI-MS Imaging in Oversampling Mode.

    Science.gov (United States)

    Wiegelmann, Marcel; Dreisewerd, Klaus; Soltwisch, Jens

    2016-12-01

    To improve the lateral resolution in matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) beyond the dimensions of the focal laser spot oversampling techniques are employed. However, few data are available on the effect of the laser spot size and its focal beam profile on the ion signals recorded in oversampling mode. To investigate these dependencies, we produced 2 times six spots with dimensions between ~30 and 200 μm. By optional use of a fundamental beam shaper, square flat-top and Gaussian beam profiles were compared. MALDI-MSI data were collected using a fixed pixel size of 20 μm and both pixel-by-pixel and continuous raster oversampling modes on a QSTAR mass spectrometer. Coronal mouse brain sections coated with 2,5-dihydroxybenzoic acid matrix were used as primary test systems. Sizably higher phospholipid ion signals were produced with laser spots exceeding a dimension of ~100 μm, although the same amount of material was essentially ablated from the 20 μm-wide oversampling pixel at all spot size settings. Only on white matter areas of the brain these effects were less apparent to absent. Scanning electron microscopy images showed that these findings can presumably be attributed to different matrix morphologies depending on tissue type. We propose that a transition in the material ejection mechanisms from a molecular desorption at large to ablation at smaller spot sizes and a concomitant reduction in ion yields may be responsible for the observed spot size effects. The combined results indicate a complex interplay between tissue type, matrix crystallization, and laser-derived desorption/ablation and finally analyte ionization. Graphical Abstract ᅟ.

  16. Analytical approach for determining beam profiles in water phantom of symmetric and asymmetric fields of wedged, blocked, and open photon beams.

    Science.gov (United States)

    Tahmasebi Birgani, Mohamad Javad; Chegeni, Nahid; Arvandi, Shole; Razmjoo Ghalaee, Sasan; Zabihzadeh, Mansoor; Khezerloo, Davood

    2013-11-04

    Nowadays, in most radiotherapy departments, the commercial treatment planning systems (TPS) used to calculate dose distributions needs to be verified; therefore, quick, easy-to-use, and low-cost dose distribution algorithms are desirable to test and verify the performance of the TPS. In this paper, we put forth an analytical method to calculate the phantom scatter contribution and depth dose on the central axis based on the equivalent square concept. Then, this method was generalized to calculate the profiles at any depth and for several field shapes - regular or irregular fields - under symmetry and asymmetry photon beam conditions. Varian 2100 C/D and Siemens Primus Plus linacs with 6 and 18 MV photon beam were used for irradiations. Percentage depth doses (PDDs) were measured for a large number of square fields for both energies and for 45° wedge, which were employed to obtain the profiles in any depth. To assess the accuracy of the calculated profiles, several profile measurements were carried out for some treatment fields. The calculated and measured profiles were compared by gamma-index calculation. All γ-index calculations were based on a 3% dose criterion and a 3 mm dose-to-agreement (DTA) acceptance criterion. The γ values were less than 1 at most points. However, the maximum γ observed was about 1.10 in the penumbra region in most fields and in the central area for the asymmetric fields. This analytical approach provides a generally quick and fairly accurate algorithm to calculate dose distribution for some treatment fields in conventional radiotherapy.

  17. Beam profile measurement with CR-39 track detector for low-energy ions

    CERN Document Server

    Sato, F; Tanaka, T; Iida, T; Yamauchi, T; Oda, K

    1999-01-01

    A CR-39 track detector was successfully used to measure the outline of thin low-energy ion beams. After the etching, the surface of the detector was examined with an observation system composed of a Normarski microscope, a CCD camera and a digital image processing computer. Beam images obtained with the system were in good agreement on the outline of the beam formed with a beam aperture. Also, the resolving power in the beam outline measurement was roughly explained from the consideration of the ion range and the etch-pit growth in the chemical etching for the CR-39 detector.

  18. Defect distribution in low-temperature molecular beam epitaxy grown Si/Si(100), improved depth profiling with monoenergetic positrons

    International Nuclear Information System (INIS)

    Szeles, C.; Asoka-Kumar, P.; Lynn, K.G.; Gossmann, H.; Unterwald, F.C.; Boone, T.

    1995-01-01

    The depth distribution of open-volume defects has been studied in Si(100) crystals grown by molecular beam epitaxy at 300 degree C by the variable-energy monoenergetic positron beam technique combined with well-controlled chemical etching. This procedure gave a 10 nm depth resolution which is a significant improvement over the inherent depth resolving power of the positron beam technique. The epitaxial layer was found to grow defect-free up to 80 nm, from the interface, where small vacancy clusters, larger than divacancies, appear. The defect density then sharply increases toward the film surface. The result clearly shows that the nucleation of small open-volume defects is a precursor state to the breakdown of epitaxy and to the evolution of an amorphous film

  19. A new high resolution neutron powder diffractometer at the Brookhaven high flux beam reactor

    International Nuclear Information System (INIS)

    Passell, L.; Bar-Ziv, S.; Gardner, D.W.; Cox, D.E.; Axe, J.D.

    1991-01-01

    A high resolution neutron powder diffractometer under construction at the Brookhaven HFBR is expected to be completed by mid-1991. The new machine will have a Ge (511) monochromator with a take-off angle of 120 o (λ=1.89A) and 64 3 He counters in the detector bank. There will be interchangeable collimators before the monochromator allowing a choice of 5 or 11' horizontal divergence, and 10 cm-high, 5' collimators in front of the detectors. In the higher resolution mode, Δd/d is expected to be about 6x10 -4 at the resolution minimum. The diffractometer is generally similar to D2B at the Institut Laue-Langevin except for the monochromator. This will consist of a vertically focussing array of segments 3x1.27 cm in dimensions cut from stacks of 20 0.43 mm wafers that have been pressed and brazed together. Preliminary measurements indicate that a mosaic width of 0.1-0.15 o and a peak reflectivity of 25% can be achieved in this way. (author) 2 figs., 22 refs

  20. Novel manufacturing method by using stainless steel pipes expanded into aluminium profiles for the ITER Neutral Beam cryopumps

    Energy Technology Data Exchange (ETDEWEB)

    Dremel, Matthias, E-mail: matthias.dremel@iter.org; Boissin, Jean-Claude; Déléage, Vincent; Quinn, Eamonn; Pearce, Robert

    2015-10-15

    This paper describes the novel engineering and manufacturing solution of stainless steel pipe expansion into aluminium extrusion profiles for use at cryogenic temperatures up to 400 K. This fabrication method will be used for the thermal radiation shields and the cryopanels of the ITER Neutral Beam cryopumps. The use of stainless steel pipes expanded into aluminium extrusion profiles is a solution that combines standard stainless steel welding procedures for the manifolds of the cooling circuits with extended aluminium structures taking advantage of the high thermal conductivity of aluminium. The cryogenic cooling circuits of the pump are a first confinement barrier in the ITER vacuum vessel and the risk of a leakage needs to be minimized as far as possible. The expansion method avoids the need of joints of dissimilar materials in the primary confinement barrier. The fabrication method and results of the prototyping of full scaled components for the ITER Neutral Beam cryopumps are outlined in this paper.

  1. Development of a Millimeter-Wave Beam Position and Profile Monitor for Transmission Efficiency Improvement in an ECRH System

    Directory of Open Access Journals (Sweden)

    Shimozuma T.

    2015-01-01

    Full Text Available In a high power Electron Cyclotron Resonance Heating (ECRH system, a long-distance and low-loss transmission system is required to realize effective heating of nuclear fusion-relevant plasmas. A millimeter-wave beam position and profile monitor, which can be used in a high-power, evacuated, and cooled transmission line, is proposed, designed, manufactured, and tested. The beam monitor consists of a reflector, Peltier-device array and a heat-sink. It was tested using simulated electric heater power or gyrotron output power. The data obtained from the monitor were well agreed with the heat source position and profile. The methods of data analysis and mode-content analysis of a propagating millimeter-wave in the corrugated wave-guide are proposed.

  2. Control of quasi-monoenergetic electron beams from laser-plasma accelerators with adjustable shock density profile

    Science.gov (United States)

    Tsai, Hai-En; Swanson, Kelly K.; Barber, Sam K.; Lehe, Remi; Mao, Hann-Shin; Mittelberger, Daniel E.; Steinke, Sven; Nakamura, Kei; van Tilborg, Jeroen; Schroeder, Carl; Esarey, Eric; Geddes, Cameron G. R.; Leemans, Wim

    2018-04-01

    The injection physics in a shock-induced density down-ramp injector was characterized, demonstrating precise control of a laser-plasma accelerator (LPA). Using a jet-blade assembly, experiments systematically varied the shock injector profile, including shock angle, shock position, up-ramp width, and acceleration length. Our work demonstrates that beam energy, energy spread, and pointing can be controlled by adjusting these parameters. As a result, an electron beam that was highly tunable from 25 to 300 MeV with 8% energy spread (ΔEFWHM/E), 1.5 mrad divergence, and 0.35 mrad pointing fluctuation was produced. Particle-in-cell simulation characterized how variation in the shock angle and up-ramp width impacted the injection process. This highly controllable LPA represents a suitable, compact electron beam source for LPA applications such as Thomson sources and free-electron lasers.

  3. Suppression of dilution in Ni-Cr-Si-B alloy cladding layer by controlling diode laser beam profile

    Science.gov (United States)

    Tanigawa, Daichi; Funada, Yoshinori; Abe, Nobuyuki; Tsukamoto, Masahiro; Hayashi, Yoshihiko; Yamazaki, Hiroyuki; Tatsumi, Yoshihiro; Yoneyama, Mikio

    2018-02-01

    A Ni-Cr-Si-B alloy layer was produced on a type 304 stainless steel plate by laser cladding. In order to produce cladding layer with smooth surface and low dilution, influence of laser beam profile on cladding layer was investigated. A laser beam with a constant spatial intensity at the focus spot was used to suppress droplet formation during the cladding layer formation. This line spot, formed with a focussing unit designed by our group, suppressed droplet generation. The layer formed using this line spot with a constant spatial intensity had a much smoother surface compared to a layer formed using a line spot with a Gaussian-like beam. In addition, the dilution of the former layer was much smaller. These results indicated that a line spot with a constant spatial intensity was more effective in producing a cladding layer with smooth surface and low dilution because it suppressed droplet generation.

  4. Beam Profile Measurement of 300 kV Ion Source Test Stand for 1 MV Electrostatic Accelerator

    International Nuclear Information System (INIS)

    Park, Sae-Hoon; Kim, Yu-Seok; Kim, Dae-Il; Kwon, Hyeok-Jung; Cho, Yong-Sub

    2015-01-01

    In this paper, RF ion source, test stand of the ion source and its test results are presented. Beam profile was measured at the downstream from the accelerating tube and at the beam dump by using BPM and wire scanner. The RF ion source of the test stand is verified by measuring the total beam current with a faraday cup in the chamber. The KOMAC (KOrea Multi-purpose Accelerator Complex) has been developing a 300 kV ion source test stand for a 1 MV electrostatic accelerator. An ion source and accelerating tube will be installed in a high pressure vessel. The ion source in a high pressure vessel requires high reliability. To confirm the stable operation of the ion source, a test stand was proposed and developed. The ion source will be tested at the test stand to verify its long-term operation conditions. The test stand consists of a 300 kV high voltage terminal, a battery for the ion source power, a 60 Hz inverter, a 200 MHz RF power, a 5 kV extraction power supply, a 300 kV accelerating tube, and a vacuum system. The beam profile monitor was installed at the downstream from the accelerating tube. Wire scanner and faraday-cup was installed at the end of the chamber

  5. Optimizing the e-beam profile of a single carbon nanotube field emission device for electric propulsion systems

    Directory of Open Access Journals (Sweden)

    Juliano Fujioka Mologni

    2010-04-01

    Full Text Available Preliminary studies on field emission (FE arrays comprised of carbon nanotubes (CNT as an electron source for electric propulsion system show remarkably promising results. Design parameters for a carbon nanotube (CNT field-emission device operating on triode configuration were numerically simulated and optimized in order to enhance the e-beam focusing quality. An additional focus gate (FG was integrated to the device to control the profile of the emitted e-beam. An axisymmetric finite element model was developed to calculate the electric field distribution on the vacuum region and a modified Fowler-Nordheim (FN equation was used to evaluate the current density emission and the effective emitter area. Afterward, a FE simulation was employed in order to calculate the trajectory of the emitted electrons and define the electron-optical properties of the e-beam. The integration of the FG was fully investigated via computational intelligence techniques. The best performance device according to our simulations presents a collimated e-beam profile that suits well for field emission displays, magnetic field detection and electron microscopy. The automated computational design tool presented in this study strongly benefits the robust design of integrated electron-optical systems for vacuum field emission applications, including electrodynamic tethering and electric propulsion systems.

  6. Beam Profile Measurement of 300 kV Ion Source Test Stand for 1 MV Electrostatic Accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sae-Hoon; Kim, Yu-Seok [Dongguk University, Gyeonju (Korea, Republic of); Kim, Dae-Il; Kwon, Hyeok-Jung; Cho, Yong-Sub [Korea Multipurpose Accelerator Complex, Gyeongju (Korea, Republic of)

    2015-10-15

    In this paper, RF ion source, test stand of the ion source and its test results are presented. Beam profile was measured at the downstream from the accelerating tube and at the beam dump by using BPM and wire scanner. The RF ion source of the test stand is verified by measuring the total beam current with a faraday cup in the chamber. The KOMAC (KOrea Multi-purpose Accelerator Complex) has been developing a 300 kV ion source test stand for a 1 MV electrostatic accelerator. An ion source and accelerating tube will be installed in a high pressure vessel. The ion source in a high pressure vessel requires high reliability. To confirm the stable operation of the ion source, a test stand was proposed and developed. The ion source will be tested at the test stand to verify its long-term operation conditions. The test stand consists of a 300 kV high voltage terminal, a battery for the ion source power, a 60 Hz inverter, a 200 MHz RF power, a 5 kV extraction power supply, a 300 kV accelerating tube, and a vacuum system. The beam profile monitor was installed at the downstream from the accelerating tube. Wire scanner and faraday-cup was installed at the end of the chamber.

  7. A new Dobson Umkehr ozone profile retrieval method optimising information content and resolution

    Science.gov (United States)

    Stone, K.; Tully, M. B.; Rhodes, S. K.; Schofield, R.

    2015-03-01

    The standard Dobson Umkehr methodology to retrieve coarse-resolution ozone profiles used by the National Oceanographic and Atmospheric Administration uses designated solar zenith angles (SZAs). However, some information may be lost if measurements lie outside the designated SZA range (between 60° and 90°), or do not conform to the fitting technique. Also, while Umkehr measurements can be taken using multiple wavelength pairs (A, C and D), past retrieval methods have focused on a single pair (C). Here we present an Umkehr inversion method that uses measurements at all SZAs (termed operational) and all wavelength pairs. (Although, we caution direct comparison to other algorithms.) Information content for a Melbourne, Australia (38° S, 145° E) Umkehr measurement case study from 28 January 1994, with SZA range similar to that designated in previous algorithms is shown. When comparing the typical single wavelength pair with designated SZAs to the operational measurements, the total degrees of freedom (independent pieces of information) increases from 3.1 to 3.4, with the majority of the information gain originating from Umkehr layers 2 + 3 and 4 (10-20 km and 25-30 km respectively). In addition to this, using all available wavelength pairs increases the total degrees of freedom to 5.2, with the most significant increases in Umkehr layers 2 + 3 to 7 and 9+ (10-40 and 45-80 km). Investigating a case from 13 April 1970 where the measurements extend beyond the 90° SZA range gives further information gain, with total degrees of freedom extending to 6.5. Similar increases are seen in the information content. Comparing the retrieved Melbourne Umkehr time series with ozonesondes shows excellent agreement in layers 2 + 3 and 4 (10-20 and 25-30 km) for both C and A + C + D-pairs. Retrievals in layers 5 and 6 (25-30 and 30-35 km) consistently show lower ozone partial column compared to ozonesondes. This is likely due to stray light effects that are not accounted for in the

  8. The digital structural analysis of cadmium selenide crystals by a method of ion beam thinning for high resolution electron microscopy

    International Nuclear Information System (INIS)

    Kanaya, Koichi; Baba, Norio; Naka, Michiaki; Kitagawa, Yukihisa; Suzuki, Kunio

    1986-01-01

    A digital processing method using a scanning densitometer system for structural analysis of electron micrographs was successfully applied to a study of cadmium selenide crystals, which were prepared by an argon-ion beam thinning method. Based on Fourier techniques for structural analysis from a computer-generated diffractogram, it was demonstrated that when cadmium selenide crystals were sufficiently thin to display the higher order diffraction spots at a high resolution approaching the atomic level, they constitute an alternative hexagonal lattice of imperfect wurtzite phase from a superposition of individual harmonic images by the enhanced scattering amplitude and corrected phase. From the structural analysis data, a Fourier synthetic lattice image was reconstructed, representing the precise location and three-dimensional arrangement of each of the atoms in the unit cell. Extensively enhanced lattice defect images of dislocations and stacking faults were also derived and shown graphically. (author)

  9. Super-resolution nanofabrication with metal-ion doped hybrid material through an optical dual-beam approach

    International Nuclear Information System (INIS)

    Cao, Yaoyu; Li, Xiangping; Gu, Min

    2014-01-01

    We apply an optical dual-beam approach to a metal-ion doped hybrid material to achieve nanofeatures beyond the optical diffraction limit. By spatially inhibiting the photoreduction and the photopolymerization, we realize a nano-line, consisting of polymer matrix and in-situ generated gold nanoparticles, with a lateral size of sub 100 nm, corresponding to a factor of 7 improvement compared to the diffraction limit. With the existence of gold nanoparticles, a plasmon enhanced super-resolution fabrication mechanism in the hybrid material is observed, which benefits in a further reduction in size of the fabricated feature. The demonstrated nanofeature in hybrid materials paves the way for realizing functional nanostructures

  10. High resolution Thomson Parabola Spectrometer for full spectral capture of multi-species ion beams

    International Nuclear Information System (INIS)

    Alejo, A.; Kar, S.; Ahmed, H.; Doria, D.; Borghesi, M.; Tebartz, A.; Ding, J.; Neumann, N.; Astbury, S.; Carroll, D. C.; Scott, G. G.; Higginson, A.; McKenna, P.; Wagner, F.; Roth, M.

    2016-01-01

    We report on the experimental characterisation of laser-driven ion beams using a Thomson Parabola Spectrometer (TPS) equipped with trapezoidally shaped electric plates, proposed by Gwynne et al. [Rev. Sci. Instrum. 85, 033304 (2014)]. While a pair of extended (30 cm long) electric plates was able to produce a significant increase in the separation between neighbouring ion species at high energies, deploying a trapezoidal design circumvented the spectral clipping at the low energy end of the ion spectra. The shape of the electric plate was chosen carefully considering, for the given spectrometer configuration, the range of detectable ion energies and species. Analytical tracing of the ion parabolas matches closely with the experimental data, which suggests a minimal effect of fringe fields on the escaping ions close to the wedged edge of the electrode. The analytical formulae were derived considering the relativistic correction required for the high energy ions to be characterised using such spectrometer.

  11. High resolution Thomson Parabola Spectrometer for full spectral capture of multi-species ion beams

    Energy Technology Data Exchange (ETDEWEB)

    Alejo, A.; Kar, S., E-mail: s.kar@qub.ac.uk; Ahmed, H.; Doria, D.; Borghesi, M. [Centre for Plasma Physics, School of Mathematics and Physics, Queen’s University Belfast, Belfast BT7 1NN (United Kingdom); Tebartz, A.; Ding, J.; Neumann, N. [Institut für Kernphysik, Technische Universität Darmstadt, Schloßgartenstrasse 9, D-64289 Darmstadt (Germany); Astbury, S.; Carroll, D. C.; Scott, G. G. [Central Laser Facility, Rutherford Appleton Laboratory, Didcot, Oxfordshire OX11 0QX (United Kingdom); Higginson, A.; McKenna, P. [Department of Physics, SUPA, University of Strathclyde, Glasgow G4 0NG (United Kingdom); Wagner, F. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Planckstraße 1, 64291 Darmstadt (Germany); Roth, M. [Institut für Kernphysik, Technische Universität Darmstadt, Schloßgartenstraße 9, D-64289 Darmstadt (Germany)

    2016-08-15

    We report on the experimental characterisation of laser-driven ion beams using a Thomson Parabola Spectrometer (TPS) equipped with trapezoidally shaped electric plates, proposed by Gwynne et al. [Rev. Sci. Instrum. 85, 033304 (2014)]. While a pair of extended (30 cm long) electric plates was able to produce a significant increase in the separation between neighbouring ion species at high energies, deploying a trapezoidal design circumvented the spectral clipping at the low energy end of the ion spectra. The shape of the electric plate was chosen carefully considering, for the given spectrometer configuration, the range of detectable ion energies and species. Analytical tracing of the ion parabolas matches closely with the experimental data, which suggests a minimal effect of fringe fields on the escaping ions close to the wedged edge of the electrode. The analytical formulae were derived considering the relativistic correction required for the high energy ions to be characterised using such spectrometer.

  12. High resolution Thomson Parabola Spectrometer for full spectral capture of multi-species ion beams

    Science.gov (United States)

    Alejo, A.; Kar, S.; Tebartz, A.; Ahmed, H.; Astbury, S.; Carroll, D. C.; Ding, J.; Doria, D.; Higginson, A.; McKenna, P.; Neumann, N.; Scott, G. G.; Wagner, F.; Roth, M.; Borghesi, M.

    2016-08-01

    We report on the experimental characterisation of laser-driven ion beams using a Thomson Parabola Spectrometer (TPS) equipped with trapezoidally shaped electric plates, proposed by Gwynne et al. [Rev. Sci. Instrum. 85, 033304 (2014)]. While a pair of extended (30 cm long) electric plates was able to produce a significant increase in the separation between neighbouring ion species at high energies, deploying a trapezoidal design circumvented the spectral clipping at the low energy end of the ion spectra. The shape of the electric plate was chosen carefully considering, for the given spectrometer configuration, the range of detectable ion energies and species. Analytical tracing of the ion parabolas matches closely with the experimental data, which suggests a minimal effect of fringe fields on the escaping ions close to the wedged edge of the electrode. The analytical formulae were derived considering the relativistic correction required for the high energy ions to be characterised using such spectrometer.

  13. IDENTIFIKASI PROFIL DASAR LAUT MENGGUNAKAN INSTRUMEN SIDE SCAN SONAR DENGAN METODE BEAM PATTERN DISCRETE-EQUI-SPACED UNSHADED LINE ARRAY

    Directory of Open Access Journals (Sweden)

    Muhammad Zainuddin Lubis

    2017-05-01

    Full Text Available Laut Punggur merupakan laut yang terletak di Batam, Kepulauan Riau yang mempunyai beragam habitat objek,dan bentuk struktur bawah laut yang memiliki dinamika laut yang sangat tinggi. Side scan sonar (SSS merupakan instrumen pengembangan sistem sonar yang mampu menunjukkan dalam gambar dua dimensional permukaan dasar laut dengan kondisi kontur, topografi, dan target secara bersamaan. Metode Beam Pattern Discrete-Equi-Spaced Unshaded Line Array digunakan untuk menghitung beam pattern dua dimensi yang tergantung pada sudut dari gelombang suara yang masuk dari sumbu array yang diterima tergantung pada sudut di mana sinar suara pada array. Penelitian ini dilakukan pada Desember 2016 di laut Punggur,Batam, Kepulauan Riau-Indonesia, dengan koordinat 104 ° 08,7102 E dan 1° 03,2448 N sampai 1 ° 03.3977 N dan 104 ° 08,8133 E, menggunakan instrumen Side Scan Sonar C-Max CM2 Tow fish dengan frekuensi 325 kHz. Hasil yang diperoleh dari perekaman terdapat 7 target, dan Beam pattern dari metode Beam Discrete-Equi-Spaced Unshaded Line Array target 4 memiliki nilai tertinggi pada directivity Pattern yaitu 21.08 dB. Hasil model beam pattern ini memiliki nilai pusat pada incidence angle (o terhadap Directivity pattern (dB tidak berada di nilai 0 ataupun pada pusat beam pattern yang dihasilkan pada target 6 dengan nilai incident angle -1.5 o dan 1.5o mengalami penurunan hingga -40 dB. Karakteristik sedimen dasar perairan di laut punggur ditemukan lebih banyak pasir. Hasil metode Beam Discrete-Equi-Spaced Unshaded Line Array ditemukan bangkai kapal tenggelam.Kata Kunci: Side Scan Sonar, Beam Pattern Discrete-Equi-Spaced Unshaded Line Array, Incidence angle, Directivity pattern IDENTIFICATION OF SEABED PROFILE USING SIDE SCAN SONAR INSTRUMENT WITH PATTERN DISCRETE-EQUI-SPACED UNSHADED LINE ARRAY METHODRiau Islands is an island that has a variety of habitat objects, and forms of submarine structures that have a very high ocean dynamics, Punggur Sea is the sea

  14. Ultrafast generation of skyrmionic defects with vortex beams: Printing laser profiles on magnets

    Science.gov (United States)

    Fujita, Hiroyuki; Sato, Masahiro

    2017-02-01

    Controlling electric and magnetic properties of matter by laser beams is actively explored in the broad region of condensed matter physics, including spintronics and magneto-optics. Here we theoretically propose an application of optical and electron vortex beams carrying intrinsic orbital angular momentum to chiral ferro- and antiferromagnets. We analyze the time evolution of spins in chiral magnets under irradiation of vortex beams by using the stochastic Landau-Lifshitz-Gilbert equation. We show that beam-driven nonuniform temperature leads to a class of ring-shaped magnetic defects, what we call skyrmion multiplex, as well as conventional skyrmions. We discuss the proper beam parameters and the optimal way of applying the beams for the creation of these topological defects. Our findings provide an ultrafast scheme of generating topological magnetic defects in a way applicable to both metallic and insulating chiral (anti-) ferromagnets.

  15. Elemental depth profiles and plasma etching rates of positive-tone electron beam resists after sequential infiltration synthesis of alumina

    Science.gov (United States)

    Ozaki, Yuki; Ito, Shunya; Hiroshiba, Nobuya; Nakamura, Takahiro; Nakagawa, Masaru

    2018-06-01

    By scanning transmission electron microscopy and energy dispersive X-ray spectroscopy (STEM–EDS), we investigated the elemental depth profiles of organic electron beam resist films after the sequential infiltration synthesis (SIS) of inorganic alumina. Although a 40-nm-thick poly(methyl methacrylate) (PMMA) film was entirely hybridized with alumina, an uneven distribution was observed near the interface between the substrate and the resist as well as near the resist surface. The uneven distribution was observed around the center of a 100-nm-thick PMMA film. The thicknesses of the PMMA and CSAR62 resist films decreased almost linearly as functions of plasma etching period. The comparison of etching rate among oxygen reactive ion etching, C3F8 reactive ion beam etching (RIBE), and Ar ion beam milling suggested that the SIS treatment enhanced the etching resistance of the electron beam resists to chemical reactions rather than to ion collisions. We proposed oxygen- and Ar-assisted C3F8 RIBE for the fabrication of silica imprint molds by electron beam lithography.

  16. Arbitrary Control of Polarization and Intensity Profiles of Diffraction-Attenuation-Resistant Beams along the Propagation Direction

    Science.gov (United States)

    Corato-Zanarella, Mateus; Dorrah, Ahmed H.; Zamboni-Rached, Michel; Mojahedi, Mo

    2018-02-01

    We report on the theory and experimental generation of a class of diffraction-attenuation-resistant beams with state of polarization (SOP) and intensity that can be controlled on demand along the propagation direction. This control is achieved by a suitable superposition of Bessel beams, whose parameters are systematically chosen based on closed-form analytic expressions provided by the frozen waves method. Using an amplitude-only spatial light modulator, we experimentally demonstrate three scenarios. In the first, the SOP of a horizontally polarized beam evolves to radial polarization and is then changed to vertical polarization, with the beam intensity held constant. In the second, we simultaneously control the SOP and the longitudinal intensity profile, which is chosen such that the beam's central ring can be switched off over predefined space regions, thus generating multiple foci with different SOPs and at different intensity levels along the propagation. Finally, the ability to control the SOP while overcoming attenuation inside lossy fluids is shown experimentally. We envision our proposed method to be of great interest for many applications, such as optical tweezers, atom guiding, material processing, microscopy, and optical communications.

  17. On the clinical spatial resolution achievable with protons and heavier charged particle radiotherapy beams

    International Nuclear Information System (INIS)

    Andreo, Pedro

    2009-01-01

    The 'sub-millimetre precision' often claimed to be achievable in protons and light ion beam therapy is analysed using the Monte Carlo code SHIELD-HIT for a broad range of energies. Based on the range of possible values and uncertainties of the mean excitation energy of water and human tissues, as well as of the composition of organs and tissues, it is concluded that precision statements deserve careful reconsideration for treatment planning purposes. It is found that the range of I-values of water stated in ICRU reports 37, 49 and 73 (1984, 1993 and 2005) for the collision stopping power formulae, namely 67 eV, 75 eV and 80 eV, yields a spread of the depth of the Bragg peak of protons and heavier charged particles (carbon ions) of up to 5 or 6 mm, which is also found to be energy dependent due to other energy loss competing interaction mechanisms. The spread is similar in protons and in carbon ions having analogous practical range. Although accurate depth-dose distribution measurements in water can be used at the time of developing empirical dose calculation models, the energy dependence of the spread causes a substantial constraint. In the case of in vivo human tissues, where distribution measurements are not feasible, the problem poses a major limitation. In addition to the spread due to the currently accepted uncertainties of their I-values, a spread of the depth of the Bragg peak due to the varying compositions of soft tissues is also demonstrated, even for cases which could be considered practically identical in clinical practice. For these, the spreads found were similar to those of water or even larger, providing support to international recommendations advising that body-tissue compositions should not be given the standing of physical constants. The results show that it would be necessary to increase the margins of a clinical target volume, even in the case of a water phantom, due to an 'intrinsic basic physics uncertainty', adding to those margins usually

  18. Beam diagnostics for low energy beams

    Directory of Open Access Journals (Sweden)

    J. Harasimowicz

    2012-12-01

    Full Text Available Low-energetic ion and antimatter beams are very attractive for a number of fundamental studies. The diagnostics of such beams, however, is a challenge due to low currents down to only a few thousands of particles per second and significant fraction of energy loss in matter at keV beam energies. A modular set of particle detectors has been developed to suit the particular beam diagnostic needs of the ultralow-energy storage ring (USR at the future facility for low-energy antiproton and ion research, accommodating very low beam intensities at energies down to 20 keV. The detectors include beam-profile monitors based on scintillating screens and secondary electron emission, sensitive Faraday cups for absolute intensity measurements, and capacitive pickups for beam position monitoring. In this paper, the design of all detectors is presented in detail and results from beam measurements are shown. The resolution limits of all detectors are described and options for further improvement summarized. Whilst initially developed for the USR, the instrumentation described in this paper is also well suited for use in other low-intensity, low-energy accelerators, storage rings, and beam lines.

  19. Using Airborne High Spectral Resolution Lidar Data to Evaluate Combined Active Plus Passive Retrievals of Aerosol Extinction Profiles

    Science.gov (United States)

    Burton, S. P.; Ferrare, R. A.; Hostetler, C. A.; Hair, J. W.; Kittaka, C.; Vaughn, M. A.; Remer, L. A.

    2010-01-01

    We derive aerosol extinction profiles from airborne and space-based lidar backscatter signals by constraining the retrieval with column aerosol optical thickness (AOT), with no need to rely on assumptions about aerosol type or lidar ratio. The backscatter data were acquired by the NASA Langley Research Center airborne High Spectral Resolution Lidar (HSRL) and by the Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP) instrument on the Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation (CALIPSO) satellite. The HSRL also simultaneously measures aerosol extinction coefficients independently using the high spectral resolution lidar technique, thereby providing an ideal data set for evaluating the retrieval. We retrieve aerosol extinction profiles from both HSRL and CALIOP attenuated backscatter data constrained with HSRL, Moderate-Resolution Imaging Spectroradiometer (MODIS), and Multiangle Imaging Spectroradiometer column AOT. The resulting profiles are compared with the aerosol extinction measured by HSRL. Retrievals are limited to cases where the column aerosol thickness is greater than 0.2 over land and 0.15 over water. In the case of large AOT, the results using the Aqua MODIS constraint over water are poorer than Aqua MODIS over land or Terra MODIS. The poorer results relate to an apparent bias in Aqua MODIS AOT over water observed in August 2007. This apparent bias is still under investigation. Finally, aerosol extinction coefficients are derived from CALIPSO backscatter data using AOT from Aqua MODIS for 28 profiles over land and 9 over water. They agree with coincident measurements by the airborne HSRL to within +/-0.016/km +/- 20% for at least two-thirds of land points and within +/-0.028/km +/- 20% for at least two-thirds of ocean points.

  20. Correlative analysis of metabolite profiling of Danggui Buxue Tang in rat biological fluids by rapid resolution LC-TOF/MS.

    Science.gov (United States)

    Li, Chang-Yin; Qi, Lian-Wen; Li, Ping

    2011-04-28

    In this work, the metabolite profiles of Danggui Buxue Tang (DBT) in rat bile and plasma were qualitatively described, and the possible metabolic pathways of DBT were subsequently proposed. Emphasis was put on correlative analysis of metabolite profiling in different biological fluids. After oral administration of DBT, bile and plasma samples were collected and pretreated by solid phase extraction. Rapid resolution liquid chromatography coupled to time-of-flight mass spectrometry (RRLC-TOFMS) was used for characterization of DBT-related compounds (parent compounds and metabolites) in biological matrices. A total of 142 metabolites were detected and tentatively identified from the drug-containing bile and plasma samples. Metabolite profiling shows that rat bile contained relatively more glutathione-derived conjugates, more saponins compounds and more diverse forms of metabolites than urine. The metabolite profile in plasma revealed that glucuronide conjugates of isoflavonoids, dimmers, acetylcysteine conjugates and parent form of phthalides, as well as saponin aglycones were the major circulating forms of DBT. Collectively, the metabolite profile analysis of DBT in different biological matrices provided a comprehensive understanding of the in vivo metabolic fates of constituents in DBT. Copyright © 2011 Elsevier B.V. All rights reserved.

  1. Measuring centimeter-resolution air temperature profiles above land and water using fiber-optic Distributed Temperature Sensing

    Science.gov (United States)

    Sigmund, Armin; Pfister, Lena; Olesch, Johannes; Thomas, Christoph K.

    2016-04-01

    The precise determination of near-surface air temperature profiles is of special importance for the characterization of airflows (e.g. cold air) and the quantification of sensible heat fluxes according to the flux-gradient similarity approach. In contrast to conventional multi-sensor techniques, measuring temperature profiles using fiber-optic Distributed Temperature Sensing (DTS) provides thousands of measurements referenced to a single calibration standard at much reduced costs. The aim of this work was to enhance the vertical resolution of Raman scatter DTS measurements up to the centimeter-scale using a novel approach for atmospheric applications: the optical fiber was helically coiled around a meshed fabric. In addition to testing the new fiber geometry, we quantified the measurement uncertainty and demonstrated the benefits of the enhanced-resolution profiles. The fiber-optic cable was coiled around a hollow column consisting of white reinforcing fabric supported by plexiglass rings every meter. Data from two columns of this type were collected for 47 days to measure air temperature vertically over 3.0 and 5.1 m over a gently inclined meadow and over and in a small lake, respectively. Both profiles had a vertical resolution of 1 cm in the lower section near the surface and 5 cm in the upper section with an along-fiber instrument-specific averaging of 1.0 m and a temporal resolution of 30 s. Measurement uncertainties, especially from conduction between reinforcing fabric and fiber-optic cable, were estimated by modeling the fiber temperature via a detailed energy balance approach. Air temperature, wind velocity and radiation components were needed as input data and measured separately. The temperature profiles revealed valuable details, especially in the lowest 1 m above surface. This was best demonstrated for nighttime observations when artefacts due to solar heating did not occur. For example, the dynamics of a cold air layer was detected in a clear night

  2. X-ray beam-shaping via deformable mirrors: surface profile and point spread function computation for Gaussian beams using physical optics.

    Science.gov (United States)

    Spiga, D

    2018-01-01

    X-ray mirrors with high focusing performances are commonly used in different sectors of science, such as X-ray astronomy, medical imaging and synchrotron/free-electron laser beamlines. While deformations of the mirror profile may cause degradation of the focus sharpness, a deliberate deformation of the mirror can be made to endow the focus with a desired size and distribution, via piezo actuators. The resulting profile can be characterized with suitable metrology tools and correlated with the expected optical quality via a wavefront propagation code or, sometimes, predicted using geometric optics. In the latter case and for the special class of profile deformations with monotonically increasing derivative, i.e. concave upwards, the point spread function (PSF) can even be predicted analytically. Moreover, under these assumptions, the relation can also be reversed: from the desired PSF the required profile deformation can be computed analytically, avoiding the use of trial-and-error search codes. However, the computation has been so far limited to geometric optics, which entailed some limitations: for example, mirror diffraction effects and the size of the coherent X-ray source were not considered. In this paper, the beam-shaping formalism in the framework of physical optics is reviewed, in the limit of small light wavelengths and in the case of Gaussian intensity wavefronts. Some examples of shaped profiles are also shown, aiming at turning a Gaussian intensity distribution into a top-hat one, and checks of the shaping performances computing the at-wavelength PSF by means of the WISE code are made.

  3. High-resolution proteomic profiling of spider venom: expanding the toxin diversity of Phoneutria nigriventer venom.

    Science.gov (United States)

    Liberato, Tarcísio; Troncone, Lanfranco Ranieri Paolo; Yamashiro, Edson T; Serrano, Solange M T; Zelanis, André

    2016-03-01

    Here we present a proteomic characterization of Phoneutria nigriventer venom. A shotgun proteomic approach allowed the identification, for the first time, of O-glycosyl hydrolases (chitinases) in P. nigriventer venom. The electrophoretic profiles under nonreducing and reducing conditions, and protein identification by mass spectrometry, indicated the presence of oligomeric toxin structures in the venom. Complementary proteomic approaches allowed for a qualitative and semi-quantitative profiling of P. nigriventer venom complexity, expanding its known venom proteome diversity.

  4. Heat Transport upon River-Water Infiltration investigated by Fiber-Optic High-Resolution Temperature Profiling

    Science.gov (United States)

    Vogt, T.; Schirmer, M.; Cirpka, O. A.

    2010-12-01

    Infiltrating river water is of high relevance for drinking water supply by river bank filtration as well as for riparian groundwater ecology. Quantifying flow patterns and velocities, however, is hampered by temporal and spatial variations of exchange fluxes. In recent years, heat has become a popular natural tracer to estimate exchange rates between rivers and groundwater. Nevertheless, field investigations are often limited by insufficient sensors spacing or simplifying assumptions such as one-dimensional flow. Our interest lies in a detailed local survey of river water infiltration at a restored river section at the losing river Thur in northeast Switzerland. Here, we measured three high-resolution temperature profiles along an assumed flow path by means of distributed temperature sensing (DTS) using fiber optic cables wrapped around poles. Moreover, piezometers were equipped with standard temperature sensors for a comparison to the DTS data. Diurnal temperature oscillations were tracked in the river bed and the riparian groundwater and analyzed by means of dynamic harmonic regression and subsequent modeling of heat transport with sinusoidal boundary conditions to quantify seepage velocities and thermal diffusivities. Compared to the standard temperature sensors, the DTS data give a higher vertical resolution, facilitating the detection of process- and structure-dependent patterns of the spatiotemporal temperature field. This advantage overcompensates the scatter in the data due to instrument noise. In particular, we could demonstrate the impact of heat conduction through the unsaturated zone on the riparian groundwater by the high resolution temperature profiles.

  5. In vitro analysis of integrated global high-resolution DNA methylation profiling with genomic imbalance and gene expression in osteosarcoma.

    Directory of Open Access Journals (Sweden)

    Bekim Sadikovic

    Full Text Available Genetic and epigenetic changes contribute to deregulation of gene expression and development of human cancer. Changes in DNA methylation are key epigenetic factors regulating gene expression and genomic stability. Recent progress in microarray technologies resulted in developments of high resolution platforms for profiling of genetic, epigenetic and gene expression changes. OS is a pediatric bone tumor with characteristically high level of numerical and structural chromosomal changes. Furthermore, little is known about DNA methylation changes in OS. Our objective was to develop an integrative approach for analysis of high-resolution epigenomic, genomic, and gene expression profiles in order to identify functional epi/genomic differences between OS cell lines and normal human osteoblasts. A combination of Affymetrix Promoter Tilling Arrays for DNA methylation, Agilent array-CGH platform for genomic imbalance and Affymetrix Gene 1.0 platform for gene expression analysis was used. As a result, an integrative high-resolution approach for interrogation of genome-wide tumour-specific changes in DNA methylation was developed. This approach was used to provide the first genomic DNA methylation maps, and to identify and validate genes with aberrant DNA methylation in OS cell lines. This first integrative analysis of global cancer-related changes in DNA methylation, genomic imbalance, and gene expression has provided comprehensive evidence of the cumulative roles of epigenetic and genetic mechanisms in deregulation of gene expression networks.

  6. Nanometric resolution in glow discharge optical emission spectroscopy and Rutherford backscattering spectrometry depth profiling of metal (Cr, Al) nitride multilayers

    International Nuclear Information System (INIS)

    Escobar Galindo, R.; Gago, R.; Fornies, E.; Munoz-Martin, A.; Climent Font, A.; Albella, J.M.

    2006-01-01

    In this work, we address the capability of glow discharge optical emission spectroscopy (GDOES) for fast and accurate depth profiling of multilayer nitride coatings down to the nanometer range. This is shown by resolving the particular case of CrN/AlN structures with individual thickness ranging from hundreds to few nanometers. In order to discriminate and identify artefacts in the GDOES depth profile due to the sputtering process, the layered structures were verified by Rutherford backscattering spectrometry (RBS) and scanning electron microscopy (SEM). The interfaces in the GDOES profiles for CrN/AlN structures are sharper than the ones measured for similar metal multilayers due to the lower sputtering rate of the nitrides. However, as a consequence of the crater shape, there is a linear degradation of the depth resolution with depth (approximately 40 nm/μm), saturating at a value of approximately half the thickness of the thinner layer. This limit is imposed by the simultaneous sputtering of consecutive layers. The ultimate GDOES depth resolution at the near surface region was estimated to be of 4-6 nm

  7. Dependence of neutron rate production with accelerator beam profile and energy range in an ADS-TRIGA RC1 reactor

    Energy Technology Data Exchange (ETDEWEB)

    Firoozabadi, M.M.; Karimi, J. [Birjand Univ. (Iran, Islamic Republic of). Dept. of Physics; Zangian, M. [Shahid Beheshti Univ., Tehran (Iran, Islamic Republic of). Nuclear Engineering Dept.

    2016-12-15

    Lead, mercury, tantalum and tungsten were used as target material for calculation of spallation processes in an ADS-TRIGA RC1 reactor. The results show that tungsten has the highest neutron production rate. Therefore it was selected as target material for further calculations. The sensitivity of neutron parameters of the ADS reactor core relative to a change of beam profile and proton energy was determined. The core assembly and parameters of the TRIGA RC1 demonstration facility were used for the calculation model. By changing the proton energy from 115 to 1 400 MeV by using the intra-nuclear cascade model of Bertini (INC-Bertini), the quantity of the relative difference in % for energy gain (G) and spallation neutron yield (Y{sub n/p}), increases to 289.99 % and 5199.15 % respectively. These changes also reduce the amount of relative difference for the proton beam current (I{sub p}) and accelerator power (P{sub acc}), 99.81 % and 81.28 % respectively. In addition, the use of a Gaussian distribution instead of a uniform distribution in the accelerator beam profile increases the quantity of relative difference for energy gain (G), net neutron multiplication (M) and spallation neutron yield (Y{sub n/p}), up to 4.93 %, 4.9 % and 5.55 % respectively.

  8. Laser Beam Propagation Through Inhomogeneous Media with Shock-Like Profiles: Modeling and Computing

    Science.gov (United States)

    Adamovsky, Grigory; Ida, Nathan

    1997-01-01

    Wave propagation in inhomogeneous media has been studied for such diverse applications as propagation of radiowaves in atmosphere, light propagation through thin films and in inhomogeneous waveguides, flow visualization, and others. In recent years an increased interest has been developed in wave propagation through shocks in supersonic flows. Results of experiments conducted in the past few years has shown such interesting phenomena as a laser beam splitting and spreading. The paper describes a model constructed to propagate a laser beam through shock-like inhomogeneous media. Numerical techniques are presented to compute the beam through such media. The results of computation are presented, discussed, and compared with experimental data.

  9. Slit x-ray beam primary dose profiles determined by analytical transport of Compton recoil electrons

    NARCIS (Netherlands)

    van't Veld, AA; van Luijk, P; Praamstra, F; van der Hulst, PC

    Accurate measurement of radiation beam penumbras is essential for conformal radiotherapy. For this purpose a detailed knowledge of the dosimeter's spatial response is required. However, experimental determination of detector spatial response is cumbersome and restricted to the specific detector type

  10. Depth profiling of residual activity of ^{237}U fragments as a range verification technique for ^{238}U primary ion beam

    Directory of Open Access Journals (Sweden)

    I. Strašík

    2012-07-01

    Full Text Available Experimental and simulation data concerning fragmentation of ^{238}U ion beam in aluminum, copper, and stainless-steel targets with the initial energy 500 and 950  MeV/u are collected in the paper. A range-verification technique based on depth profiling of residual activity is presented. The irradiated targets were constructed in the stacked-foil geometry and analyzed using gamma-ray spectroscopy. One of the purposes of these experiments was depth profiling of residual activity of induced nuclides and projectile fragments. Among the projectile fragments, special attention is paid to the ^{237}U isotope that has a range very close to the range of the primary ^{238}U ions. Therefore, the depth profiling of the ^{237}U isotope can be utilized for experimental verification of the ^{238}U primary-beam range, which is demonstrated and discussed in the paper. The experimental data are compared with computer simulations by FLUKA, SRIM, and ATIMA, as well as with complementary experiments.

  11. Control of the ultrasonic beam transmitted through an irregular profile using a smart flexible transducer: modelling an application

    Energy Technology Data Exchange (ETDEWEB)

    Roy, O.; Mahaut, S.; Casula, O. [CEA Fontenay aux Roses, DRT/LIST/DECS/STA/LMUS, 92 (France)

    2001-07-01

    In most of industries as aeronautics, aerospace and nuclear, the main part of the ultrasonic testing is carried out directly in touch with the inspected component. Among others, the cooling piping of French pressurized water reactor comprises many welding components with complex geometry: elbows, butt welds, nozzles. In service inspections of such components performed with conventional ultrasonic contact transducers present limited performances. Variations in sensitivity are produced by unmatched contact on irregular surface, which results in poor detection performances. In addition, the beam orientation transmitted through complex interfaces cannot be totally controlled, because of the disorientations suffered by the transducer during its displacement. As a result, a possible defect cannot be correctly detected, positioned and characterized. At last, the geometry of some components limits the displacement of the transducer, resulting in an uncovered scan area. To overcome these difficulties and to improve the performances of such inspections, the CEA, supported by the safety authorities (IPSN), has developed a new concept of phased array. Recent studies have been made to obtain further performances improvements of this system, including instrumentation development and a new phased array design. Inspections have been performed on a specimen containing artificial defects under a realistic profile, with an adaptive mode to compensate the effect of the irregular profile. Experimental results, displayed using specific imaging, show the ability of this system to detect and characterize defects under irregular profiles, using longitudinal or shear waves in a fully mastered beam. (authors)

  12. A model to generate beam profiles of the Varian Clinac 4 for three-dimensional dose calculation: open fields

    International Nuclear Information System (INIS)

    Lam, K.S.; Lam, W.C.

    1984-01-01

    For the Clinac 4, open field profiles measured in the principal plane have higher intensity ''horns'' than those in off-axis planes. The maximum deviation occurs at 1-cm depth, where in the worst case of large field sizes and off-axis distances the deviation can be as high as 16% in the region near the horns. A model is proposed to generate open field beam profiles in off-axis planes, based on measured profiles in the transverse principal plane and in the largest field size diagonal plane of the machine. Within the central 90% portion of the field, the maximum deviation of the generated profiles from the measured ones at the same off-axis distance varies from about 3% at 1-cm depth to about 2% at 13-cm depth and then increases to less than 5% at 25-cm depth, even for very large field sizes and off-axis distances. Very little additional computer time and data storage are required for this procedure. Using these profiles, the Milan and Bentley method can be extended to three-dimensional treatment planning with good accuracy

  13. EFFECTS OF NITROGEN PHOTOABSORPTION CROSS SECTION RESOLUTION ON MINOR SPECIES VERTICAL PROFILES IN TITAN’S UPPER ATMOSPHERE

    International Nuclear Information System (INIS)

    Luspay-Kuti, A.; Mandt, K. E.; Greathouse, T. K.; Plessis, S.

    2015-01-01

    The significant variations in both measured and modeled densities of minor species in Titan’s atmosphere call for the evaluation of possible influencing factors in photochemical modeling. The effect of nitrogen photoabsorption cross section selection on the modeled vertical profiles of minor species is analyzed here, with particular focus on C 2 H 6 and HCN. Our results show a clear impact of cross sections used on all neutral and ion species studied. Affected species include neutrals and ions that are not primary photochemical products, including species that do not even contain nitrogen. The results indicate that photochemical models that employ low-resolution cross sections may significantly miscalculate the vertical profiles of minor species. Such differences are expected to have important implications for Titan’s overall atmospheric structure and chemistry

  14. EFFECTS OF NITROGEN PHOTOABSORPTION CROSS SECTION RESOLUTION ON MINOR SPECIES VERTICAL PROFILES IN TITAN’S UPPER ATMOSPHERE

    Energy Technology Data Exchange (ETDEWEB)

    Luspay-Kuti, A.; Mandt, K. E.; Greathouse, T. K. [Space Science and Engineering Division, Southwest Research Institute, 6220 Culebra Road, San Antonio, TX 78238 (United States); Plessis, S., E-mail: aluspaykuti@swri.edu [ICES, The University of Texas at Austin, 201 East 24th Street, Austin, TX 78712 (United States)

    2015-03-01

    The significant variations in both measured and modeled densities of minor species in Titan’s atmosphere call for the evaluation of possible influencing factors in photochemical modeling. The effect of nitrogen photoabsorption cross section selection on the modeled vertical profiles of minor species is analyzed here, with particular focus on C{sub 2}H{sub 6} and HCN. Our results show a clear impact of cross sections used on all neutral and ion species studied. Affected species include neutrals and ions that are not primary photochemical products, including species that do not even contain nitrogen. The results indicate that photochemical models that employ low-resolution cross sections may significantly miscalculate the vertical profiles of minor species. Such differences are expected to have important implications for Titan’s overall atmospheric structure and chemistry.

  15. Profiling of modified nucleosides from ribonucleic acid digestion by supercritical fluid chromatography coupled to high resolution mass spectrometry.

    Science.gov (United States)

    Laboureur, Laurent; Guérineau, Vincent; Auxilien, Sylvie; Yoshizawa, Satoko; Touboul, David

    2018-02-16

    A method based on supercritical fluid chromatography coupled to high resolution mass spectrometry for the profiling of canonical and modified nucleosides was optimized, and compared to classical reverse-phase liquid chromatography in terms of separation, number of detected modified nucleosides and sensitivity. Limits of detection and quantification were measured using statistical method and quantifications of twelve nucleosides of a tRNA digest from E. coli are in good agreement with previously reported data. Results highlight the complementarity of both separation techniques to cover the largest view of nucleoside modifications for forthcoming epigenetic studies. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Aircraft micro-doppler feature extraction from high range resolution profiles

    CSIR Research Space (South Africa)

    Berndt, RJ

    2015-10-01

    Full Text Available The use of high range resolution measurements and the micro-Doppler effect produced by rotating or vibrating parts of a target has been well documented. This paper presents a technique for extracting features related to helicopter rotors...

  17. Using high resolution tritium profiles to quantify the effects of melt on two Spitsbergen ice cores

    NARCIS (Netherlands)

    van der Wel, L.G.; Streurman, H.J.; Isaksson, E.; Helsen, M.M.; van de Wal, R.S.W.; Martma, T.; Pohjola, V.A.; Moore, J.C.; Meijer, H.A.J.

    2011-01-01

    Ice cores from small ice caps provide valuable climatic information, additional to that of Greenland and Antarctica. However, their integrity is usually compromised by summer meltwater percolation. To determine to what extent this can affect such ice cores, we performed high-resolution tritium

  18. 3D printing for orthopedic applications: from high resolution cone beam CT images to life size physical models

    Science.gov (United States)

    Jackson, Amiee; Ray, Lawrence A.; Dangi, Shusil; Ben-Zikri, Yehuda K.; Linte, Cristian A.

    2017-03-01

    With increasing resolution in image acquisition, the project explores capabilities of printing toward faithfully reflecting detail and features depicted in medical images. To improve safety and efficiency of orthopedic surgery and spatial conceptualization in training and education, this project focused on generating virtual models of orthopedic anatomy from clinical quality computed tomography (CT) image datasets and manufacturing life-size physical models of the anatomy using 3D printing tools. Beginning with raw micro CT data, several image segmentation techniques including thresholding, edge recognition, and region-growing algorithms available in packages such as ITK-SNAP, MITK, or Mimics, were utilized to separate bone from surrounding soft tissue. After converting the resulting data to a standard 3D printing format, stereolithography (STL), the STL file was edited using Meshlab, Netfabb, and Meshmixer. The editing process was necessary to ensure a fully connected surface (no loose elements), positive volume with manifold geometry (geometry possible in the 3D physical world), and a single, closed shell. The resulting surface was then imported into a "slicing" software to scale and orient for printing on a Flashforge Creator Pro. In printing, relationships between orientation, print bed volume, model quality, material use and cost, and print time were considered. We generated anatomical models of the hand, elbow, knee, ankle, and foot from both low-dose high-resolution cone-beam CT images acquired using the soon to be released scanner developed by Carestream, as well as scaled models of the skeletal anatomy of the arm and leg, together with life-size models of the hand and foot.

  19. Non-Cooperative Target Recognition by Means of Singular Value Decomposition Applied to Radar High Resolution Range Profiles

    Directory of Open Access Journals (Sweden)

    Patricia López-Rodríguez

    2014-12-01

    Full Text Available Radar high resolution range profiles are widely used among the target recognition community for the detection and identification of flying targets. In this paper, singular value decomposition is applied to extract the relevant information and to model each aircraft as a subspace. The identification algorithm is based on angle between subspaces and takes place in a transformed domain. In order to have a wide database of radar signatures and evaluate the performance, simulated range profiles are used as the recognition database while the test samples comprise data of actual range profiles collected in a measurement campaign. Thanks to the modeling of aircraft as subspaces only the valuable information of each target is used in the recognition process. Thus, one of the main advantages of using singular value decomposition, is that it helps to overcome the notable dissimilarities found in the shape and signal-to-noise ratio between actual and simulated profiles due to their difference in nature. Despite these differences, the recognition rates obtained with the algorithm are quite promising.

  20. Assessing the influence of the temporal resolution of electrical load and PV generation profiles on self-consumption and sizing of PV-battery systems

    International Nuclear Information System (INIS)

    Beck, T.; Kondziella, H.; Huard, G.; Bruckner, T.

    2016-01-01

    Highlights: • MILP optimization model for operation and investment of PV-battery systems. • Use of high resolution (10 s) electrical household load and PV generation profiles. • Analysis of influence of temporal resolution on self-consumption and optimal sizing. • Electrical load profile characteristics influence required temporal resolution. - Abstract: The interest in self-consumption of electricity generated by rooftop photovoltaic systems has grown in recent years, fueled by decreasing levelized costs of electricity and feed-in tariffs as well as increasing end customer electricity prices in the residential sector. This also fostered research on grid-connected PV-battery storage systems, which are a promising technology to increase self-consumption. In this paper a mixed-integer linear optimization model of a PV-battery system that minimizes the total discounted operating and investment costs is developed. The model is employed to study the effect of the temporal resolution of electrical load and PV generation profiles on the rate of self-consumption and the optimal sizing of PV and PV-battery systems. In contrast to previous studies high resolution (10 s) measured input data for both PV generation and electrical load profiles is used for the analysis. The data was obtained by smart meter measurements in 25 different households in Germany. It is shown that the temporal resolution of load profiles is more critical for the accuracy of the determination of self-consumption rates than the resolution of the PV generation. For PV-systems without additional storage accurate results can be obtained by using 15 min solar irradiation data. The required accuracy for the electrical load profiles depends strongly on the load profile characteristics. While good results can be obtained with 60 s for all electrical load profiles, 15 min data can still be sufficient for load profiles that do not exhibit most of their electricity consumption at power levels above 2 k

  1. Resolution of aviation forensic toxicology findings with the aid of DNA profiling.

    Science.gov (United States)

    Chaturvedi, Arvind K; Craft, Kristi J; Kupfer, Doris M; Burian, Dennis; Canfield, Dennis V

    2011-03-20

    Body components of aviation accident fatalities are often scattered, disintegrated, commingled, contaminated, and/or putrefied at accident scenes. These situations may impose difficulties in victim identification/tissue matching. The prevalence of misidentification in relation to aviation accident forensic toxicology has not been well established. Therefore, the Civil Aerospace Medical Institute (CAMI) toxicology database was searched for the 1998-2008 period for those cases wherein DNA profiling was performed to resolve identity issue of the samples submitted to CAMI for toxicological evaluation. During this period, biological samples from the casualties of a total of 3523 accidents were submitted to CAMI. The submitted samples were primarily from pilots. Out of the 3523 accidents, at least, one fatality had occurred in 3366 (≈ 96%) accidents; thus, these accidents were considered fatal accidents. Accordingly, biological samples from 3319 pilots (3319 of the 3366 accidents) were received at CAMI for toxicological testing. Of these 3319 pilots, 3275 (≈ 99%) were fatally injured. DNA profiling was performed in 15 (≈ 0.5%) of the 3319 accidents. The profiling was conducted upon the requests of families in two accidents, accident investigators in three, and pathologists in four. In six accidents, contradictory toxicological findings led CAMI to initiate DNA profiling. The requests made by families and investigators were primarily triggered by inconsistency between the toxicological results and the history of drug use of the victims, while by pathologists because of commingling of samples. In three (20%) of the 15 accidents, at least one submitted sample was misidentified or mislabeled. The present study demonstrated that the number of aviation accident cases requiring DNA profiling was small and this DNA approach was effectively applied in resolving aviation toxicology findings associated with those accidents. Published by Elsevier Ireland Ltd.

  2. Ion beam studies. Part 5 - the computer simulation of composite ion implantation profiles

    International Nuclear Information System (INIS)

    Freeman, J.H.; Booker, D.V.

    1977-01-01

    The computer simulation of composite ion implantation profiles produced by continuous energy programming and by discrete multiple dose doping is described. It is shown that precise matching of the computed profile to various uniform and power-law distributions can be achieved. (author)

  3. High resolution spectroscopy of 1,2-difluoroethane in a molecular beam: A case study of vibrational mode-coupling

    Science.gov (United States)

    Mork, Steven W.; Miller, C. Cameron; Philips, Laura A.

    1992-09-01

    The high resolution infrared spectrum of 1,2-difluoroethane (DFE) in a molecular beam has been obtained over the 2978-2996 cm-1 spectral region. This region corresponds to the symmetric combination of asymmetric C-H stretches in DFE. Observed rotational fine structure indicates that this C-H stretch is undergoing vibrational mode coupling to a single dark mode. The dark mode is split by approximately 19 cm-1 due to tunneling between the two identical gauche conformers. The mechanism of the coupling is largely anharmonic with a minor component of B/C plane Coriolis coupling. Effects of centrifugal distortion along the molecular A-axis are also observed. Analysis of the fine structure identifies the dark state as being composed of C-C torsion, CCF bend, and CH2 rock. Coupling between the C-H stretches and the C-C torsion is of particular interest because DFE has been observed to undergo vibrationally induced isomerization from the gauche to trans conformer upon excitation of the C-H stretch.

  4. Geometric and dosimetric verification of step-and-shoot modulated fields with a new fast and high resolution beam imaging system

    International Nuclear Information System (INIS)

    Bindoni, Luca

    2005-01-01

    A technique for geometric and dosimetric pretreatment verification of step-and-shoot intensity modulated radiotherapy treatments (IMRT) using a beam imaging system (BIS) made up of a charge-coupled device (CCD) digital camera optically coupled with a metal-plate/phosphor screen is described. Some physical properties of BIS were investigated in order to demonstrate its capability to perform measurements with a high spatial resolution and a high sampling rate. High-speed imaging, with a minimum charge integration time on the CCD of 120 ms, can be performed. The study of the signal-to-noise ratio as a function of sampling time is presented. In-plane and cross-line pixel size was measured to be 0.368±0.004 mm/pixel, which agrees within 0.5% of the manufacturer value of 0.366 mm. Spatial linearity results are very good and there are no detectable image distortions on whole 30x30 cm 2 detector area. A software routine was written to automatically extract positions of the collimator leaves from the images of the field shaped by the multileaf collimator (MLC) and also to compare them with the coordinates from the treatment planning system (TPS), thus directly testing both the MLC positioning and the treatment parameters transfer from TPS to the linear accelerator in a fast and precise way. The dosimetric capabilities (characteristics) of the imaging device for photon beams with energies of 6 and 15 MV were studied. Additional plexiglass buildup layers, depending on x-ray energy, were needed to reach maximum efficiency. The energy dependence of the BIS response versus dose and dose rate was found to be linear over a wide range. Relative output factors of BIS as a function of field size, compared with values measured with an ionization chamber, were in good accord for smaller field sizes ≤10x10 cm 2 but showed differences up to 4% for all the energies at the respective buildup depth for bigger fields. Square field profiles at water-equivalent buildup depths, extracted

  5. Te and ne profiles on JFT-2M plasma with the highest spatial resolution TV Thomson scattering system

    International Nuclear Information System (INIS)

    Yamauchi, T.

    1993-01-01

    A high spatial resolution TV Thomson scattering system was constructed on JFT-2M tokamak. This system is similar to those used at PBX-M and TFTR. These systems are providing complete profiles of Te and ne at a single time during a plasma discharge. The characteristics of JFT-2M TVTS are as follows: 1. Measured points are composed of not only 81 points for the scattered light and plasma light, whose time difference is 2 ms, but also 10 points for plasma light measured at the same time with scattered light. 2. Spatial resolution is 0.86 cm, which is higher than any other Thomson scattering system. 3. Sensitivity of detector composed of image intensifier tubes and CCD is as high as that of photomultiplier tube. Te and ne profiles have been measured over one year on JFT-2M. The line-averaged electron density measured was in the region of 5x10 12 cm -3 - 7x10 13 cm -3 and the measured electron temperature was in the region of 50 eV -1.2 keV. (author) 7 refs., 7 figs., 1 tab

  6. Cerebrospinal fluid metabolic profiles in multiple sclerosis and degenerative dementias obtained by high resolution proton magnetic resonance spectroscopy

    International Nuclear Information System (INIS)

    Vion-Dury, J.; Confort-Gouny, S.; Maillet, S.; Cozzone, P.J.; Nicoli, F.; Gastaut, J.L.

    1996-01-01

    We have analyzed the cerebrospinal fluid (CSF) of 19 patients with multiple sclerosis (MS), 12 patients with degenerative dementia and 17 control patients using in vitro high resolution proton magnetic resonance spectroscopy (MRS) at 400 MHz. The CSF metabolic profile is slightly modified in MS patients (increased lactate and fructose concentrations, decreased creatinine and phenylalanine concentrations) and is not correlated with the intensity of the intrathecal inflammation. Proton MRS of CSF does not differentiate relapsing-remitting MS and primary progressive MS. We have not detected any specific abnormal resonance in native or lyophilized CSF. The CSF metabolic profile of demented patients is much more altered (increased concentration of lactate, pyruvate, alanine, lysine, valine, leucine-isoleucine, tyrosine, glutamine) and is in agreement with a brain oxidative metabolism impairment as already described in Alzheimer's disease. Unassigned abnormal but non specific or constant resonances have been detected on MR spectra of demented patients. CSF inositol concentration is also increased in the CSF of patients with Alzheimer's disease. In vitro high resolution proton MRS of the CSF constitutes a new and original way to explore CSF for the differential and/or early diagnosis of dementias, as a complement to in vivo proton cerebral MRS. (authors). 22 refs., 4 figs., 2 tabs

  7. Cerebrospinal fluid metabolic profiles in multiple sclerosis and degenerative dementias obtained by high resolution proton magnetic resonance spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Vion-Dury, J.; Confort-Gouny, S.; Maillet, S.; Cozzone, P.J. [Centre Hospitalier Universitaire de la Timone, 13 - Marseille (France); Nicoli, F. [Centre Hospitalier Universitaire de la Timone, 13 - Marseille (France)]|[Hopital Sainte-Marguerite, 13 - Marseille (France); Gastaut, J.L. [Hopital Sainte-Marguerite, 13 - Marseille (France)

    1996-07-01

    We have analyzed the cerebrospinal fluid (CSF) of 19 patients with multiple sclerosis (MS), 12 patients with degenerative dementia and 17 control patients using in vitro high resolution proton magnetic resonance spectroscopy (MRS) at 400 MHz. The CSF metabolic profile is slightly modified in MS patients (increased lactate and fructose concentrations, decreased creatinine and phenylalanine concentrations) and is not correlated with the intensity of the intrathecal inflammation. Proton MRS of CSF does not differentiate relapsing-remitting MS and primary progressive MS. We have not detected any specific abnormal resonance in native or lyophilized CSF. The CSF metabolic profile of demented patients is much more altered (increased concentration of lactate, pyruvate, alanine, lysine, valine, leucine-isoleucine, tyrosine, glutamine) and is in agreement with a brain oxidative metabolism impairment as already described in Alzheimer`s disease. Unassigned abnormal but non specific or constant resonances have been detected on MR spectra of demented patients. CSF inositol concentration is also increased in the CSF of patients with Alzheimer`s disease. In vitro high resolution proton MRS of the CSF constitutes a new and original way to explore CSF for the differential and/or early diagnosis of dementias, as a complement to in vivo proton cerebral MRS. (authors). 22 refs., 4 figs., 2 tabs.

  8. Triacylglycerol profiling of microalgae strains for biofuel feedstock by liquid chromatography-high-resolution mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    MacDougall, Karen M.; McNichol, Jesse; McGinn, Patrick J.; O' Leary, Stephen J.B.; Melanson, Jeremy E. [Institute for Marine Biosciences, National Research Council of Canada, Halifax, NS (Canada)

    2011-11-15

    Biofuels from photosynthetic microalgae are quickly gaining interest as a viable carbon-neutral energy source. Typically, characterization of algal feedstock involves breaking down triacylglycerols (TAG) and other intact lipids, followed by derivatization of the fatty acids to fatty acid methyl esters prior to analysis by gas chromatography (GC). However, knowledge of the intact lipid profile could offer significant advantages for discovery stage biofuel research such as the selection of an algal strain or the optimization of growth and extraction conditions. Herein, lipid extracts from microalgae were directly analyzed by ultra-high pressure liquid chromatography-mass spectrometry (UHPLC-MS) using a benchtop Orbitrap mass spectrometer. Phospholipids, glycolipids, and TAGs were analyzed in the same chromatographic run, using a combination of accurate mass and diagnostic fragment ions for identification. Using this approach, greater than 100 unique TAGs were identified over the six algal strains studied and TAG profiles were obtained to assess their potential for biofuel applications. Under the growth conditions employed, Botryococcus braunii and Scenedesmus obliquus yielded the most comprehensive TAG profile with a high abundance of TAGs containing oleic acid. (orig.)

  9. Operating results for the beam profile monitor system currently in use at Bevalac Facility

    International Nuclear Information System (INIS)

    Stover, G.; Fowler, K.

    1987-03-01

    Three stations of a soon to be completed multi-station, multi-wire beam monitoring system have been installed in the Bevalac transfer line. The following article will provide a cursory analysis of the electronic circuitry, discuss new design additions and summarize the operating results obtained over the last year

  10. Optimizing laser beam profiles using micro-lens arrays for efficient material processing: applications to solar cells

    Science.gov (United States)

    Hauschild, Dirk; Homburg, Oliver; Mitra, Thomas; Ivanenko, Mikhail; Jarczynski, Manfred; Meinschien, Jens; Bayer, Andreas; Lissotschenko, Vitalij

    2009-02-01

    High power laser sources are used in various production tools for microelectronic products and solar cells, including the applications annealing, lithography, edge isolation as well as dicing and patterning. Besides the right choice of the laser source suitable high performance optics for generating the appropriate beam profile and intensity distribution are of high importance for the right processing speed, quality and yield. For industrial applications equally important is an adequate understanding of the physics of the light-matter interaction behind the process. In advance simulations of the tool performance can minimize technical and financial risk as well as lead times for prototyping and introduction into series production. LIMO has developed its own software founded on the Maxwell equations taking into account all important physical aspects of the laser based process: the light source, the beam shaping optical system and the light-matter interaction. Based on this knowledge together with a unique free-form micro-lens array production technology and patented micro-optics beam shaping designs a number of novel solar cell production tool sub-systems have been built. The basic functionalities, design principles and performance results are presented with a special emphasis on resilience, cost reduction and process reliability.

  11. Astigmatism-free high-brightness 1060 nm edge-emitting lasers with narrow circular beam profile.

    Science.gov (United States)

    Miah, Md Jarez; Kalosha, Vladimir P; Bimberg, Dieter; Pohl, Johannes; Weyers, Markus

    2016-12-26

    1060 nm high-brightness vertical broad-area edge-emitting lasers providing anastigmatic high optical power into a narrow circular beam profile are demonstrated. Ridge-waveguide (RW) lasers yield record 2.2 W single-transverse mode power in the 1060-nm wavelength range under continuous-wave (cw) operation at room temperature with excellent beam quality factor M2 ≤ 2. Independent of operating current the astigmatism is only 2.5 µm. 3 mm long broad-area (BA) lasers produce a θvert as narrow as 9° full width at half maximum, which agrees well with our simulation results, being insensitive to drive current. 5 mm long BA lasers deliver highest ever reported cw 12 W multimode output power among lasers showing θvert <10° in the 1060-nm wavelength range. The emitted laser beams from both RW and BA lasers show a perfect circular shape with ≤10° divergence angle at record 2.1 W and 4.2 W cw-mode output power, respectively.

  12. Analytical solutions for thermal transient profile in solid target irradiated with low energy and high beam current protons

    International Nuclear Information System (INIS)

    Oliveira, Henrique B. de; Brazao, Nei G.; Sciani, Valdir

    2009-01-01

    There were obtained analytical solutions for thermal transient in solid targets, used in short half-life radioisotopes production, when irradiated with low energy and high beam current protons, in the cyclotron accelerator Cyclone 30 of the Institute for Energy and Nuclear Research (IPEN/CNEN-SP). The beam spatial profile was considered constant and the time depended heat distribution equation was resolved for a continuous particles flow entering the target. The problem was divided into two stages: a general solution was proposed which is the sum of two functions, the first one related to the thermal equilibrium situation and the second one related to a time dependent function that was determinate by the setting of the contour conditions and the initial conditions imposed by the real problem. By that one got an analytic function for a complete description of the heat transport phenomenon inside the targets. There were used both, numerical and symbolic computation methods, to obtain temperature maps and thermal gradients and the results showed an excellent agreement when compared with purely numerical models. The results were compared with obtained data from Gallium-67 and Thallium-201 irradiation routines conducted by the IPEN Cyclotrons accelerators center, showing excellent agreement. The objective of this paper is to develop solid targets irradiation systems (metals and oxides) so that one can operate with high levels of current beam, minimizing the irradiation time and maximizing the final returns. (author)

  13. Towards automatic metabolomic profiling of high-resolution one-dimensional proton NMR spectra

    Energy Technology Data Exchange (ETDEWEB)

    Mercier, Pascal; Lewis, Michael J.; Chang, David, E-mail: dchang@chenomx.com [Chenomx Inc (Canada); Baker, David [Pfizer Inc (United States); Wishart, David S. [University of Alberta, Department of Computing Science and Biological Sciences (Canada)

    2011-04-15

    Nuclear magnetic resonance (NMR) and Mass Spectroscopy (MS) are the two most common spectroscopic analytical techniques employed in metabolomics. The large spectral datasets generated by NMR and MS are often analyzed using data reduction techniques like Principal Component Analysis (PCA). Although rapid, these methods are susceptible to solvent and matrix effects, high rates of false positives, lack of reproducibility and limited data transferability from one platform to the next. Given these limitations, a growing trend in both NMR and MS-based metabolomics is towards targeted profiling or 'quantitative' metabolomics, wherein compounds are identified and quantified via spectral fitting prior to any statistical analysis. Despite the obvious advantages of this method, targeted profiling is hindered by the time required to perform manual or computer-assisted spectral fitting. In an effort to increase data analysis throughput for NMR-based metabolomics, we have developed an automatic method for identifying and quantifying metabolites in one-dimensional (1D) proton NMR spectra. This new algorithm is capable of using carefully constructed reference spectra and optimizing thousands of variables to reconstruct experimental NMR spectra of biofluids using rules and concepts derived from physical chemistry and NMR theory. The automated profiling program has been tested against spectra of synthetic mixtures as well as biological spectra of urine, serum and cerebral spinal fluid (CSF). Our results indicate that the algorithm can correctly identify compounds with high fidelity in each biofluid sample (except for urine). Furthermore, the metabolite concentrations exhibit a very high correlation with both simulated and manually-detected values.

  14. Towards automatic metabolomic profiling of high-resolution one-dimensional proton NMR spectra

    International Nuclear Information System (INIS)

    Mercier, Pascal; Lewis, Michael J.; Chang, David; Baker, David; Wishart, David S.

    2011-01-01

    Nuclear magnetic resonance (NMR) and Mass Spectroscopy (MS) are the two most common spectroscopic analytical techniques employed in metabolomics. The large spectral datasets generated by NMR and MS are often analyzed using data reduction techniques like Principal Component Analysis (PCA). Although rapid, these methods are susceptible to solvent and matrix effects, high rates of false positives, lack of reproducibility and limited data transferability from one platform to the next. Given these limitations, a growing trend in both NMR and MS-based metabolomics is towards targeted profiling or “quantitative” metabolomics, wherein compounds are identified and quantified via spectral fitting prior to any statistical analysis. Despite the obvious advantages of this method, targeted profiling is hindered by the time required to perform manual or computer-assisted spectral fitting. In an effort to increase data analysis throughput for NMR-based metabolomics, we have developed an automatic method for identifying and quantifying metabolites in one-dimensional (1D) proton NMR spectra. This new algorithm is capable of using carefully constructed reference spectra and optimizing thousands of variables to reconstruct experimental NMR spectra of biofluids using rules and concepts derived from physical chemistry and NMR theory. The automated profiling program has been tested against spectra of synthetic mixtures as well as biological spectra of urine, serum and cerebral spinal fluid (CSF). Our results indicate that the algorithm can correctly identify compounds with high fidelity in each biofluid sample (except for urine). Furthermore, the metabolite concentrations exhibit a very high correlation with both simulated and manually-detected values.

  15. High-Resolution Analysis of Coronavirus Gene Expression by RNA Sequencing and Ribosome Profiling.

    Science.gov (United States)

    Irigoyen, Nerea; Firth, Andrew E; Jones, Joshua D; Chung, Betty Y-W; Siddell, Stuart G; Brierley, Ian

    2016-02-01

    Members of the family Coronaviridae have the largest genomes of all RNA viruses, typically in the region of 30 kilobases. Several coronaviruses, such as Severe acute respiratory syndrome-related coronavirus (SARS-CoV) and Middle East respiratory syndrome-related coronavirus (MERS-CoV), are of medical importance, with high mortality rates and, in the case of SARS-CoV, significant pandemic potential. Other coronaviruses, such as Porcine epidemic diarrhea virus and Avian coronavirus, are important livestock pathogens. Ribosome profiling is a technique which exploits the capacity of the translating ribosome to protect around 30 nucleotides of mRNA from ribonuclease digestion. Ribosome-protected mRNA fragments are purified, subjected to deep sequencing and mapped back to the transcriptome to give a global "snap-shot" of translation. Parallel RNA sequencing allows normalization by transcript abundance. Here we apply ribosome profiling to cells infected with Murine coronavirus, mouse hepatitis virus, strain A59 (MHV-A59), a model coronavirus in the same genus as SARS-CoV and MERS-CoV. The data obtained allowed us to study the kinetics of virus transcription and translation with exquisite precision. We studied the timecourse of positive and negative-sense genomic and subgenomic viral RNA production and the relative translation efficiencies of the different virus ORFs. Virus mRNAs were not found to be translated more efficiently than host mRNAs; rather, virus translation dominates host translation at later time points due to high levels of virus transcripts. Triplet phasing of the profiling data allowed precise determination of translated reading frames and revealed several translated short open reading frames upstream of, or embedded within, known virus protein-coding regions. Ribosome pause sites were identified in the virus replicase polyprotein pp1a ORF and investigated experimentally. Contrary to expectations, ribosomes were not found to pause at the ribosomal

  16. High-Resolution Analysis of Coronavirus Gene Expression by RNA Sequencing and Ribosome Profiling.

    Directory of Open Access Journals (Sweden)

    Nerea Irigoyen

    2016-02-01

    Full Text Available Members of the family Coronaviridae have the largest genomes of all RNA viruses, typically in the region of 30 kilobases. Several coronaviruses, such as Severe acute respiratory syndrome-related coronavirus (SARS-CoV and Middle East respiratory syndrome-related coronavirus (MERS-CoV, are of medical importance, with high mortality rates and, in the case of SARS-CoV, significant pandemic potential. Other coronaviruses, such as Porcine epidemic diarrhea virus and Avian coronavirus, are important livestock pathogens. Ribosome profiling is a technique which exploits the capacity of the translating ribosome to protect around 30 nucleotides of mRNA from ribonuclease digestion. Ribosome-protected mRNA fragments are purified, subjected to deep sequencing and mapped back to the transcriptome to give a global "snap-shot" of translation. Parallel RNA sequencing allows normalization by transcript abundance. Here we apply ribosome profiling to cells infected with Murine coronavirus, mouse hepatitis virus, strain A59 (MHV-A59, a model coronavirus in the same genus as SARS-CoV and MERS-CoV. The data obtained allowed us to study the kinetics of virus transcription and translation with exquisite precision. We studied the timecourse of positive and negative-sense genomic and subgenomic viral RNA production and the relative translation efficiencies of the different virus ORFs. Virus mRNAs were not found to be translated more efficiently than host mRNAs; rather, virus translation dominates host translation at later time points due to high levels of virus transcripts. Triplet phasing of the profiling data allowed precise determination of translated reading frames and revealed several translated short open reading frames upstream of, or embedded within, known virus protein-coding regions. Ribosome pause sites were identified in the virus replicase polyprotein pp1a ORF and investigated experimentally. Contrary to expectations, ribosomes were not found to pause at the

  17. Video profile monitor diagnostic system for GTA

    International Nuclear Information System (INIS)

    Sandovil, D.P.; Garcia, R.C.; Gilpatrick, J.D.; Johnson, K.F.; Shinas, M.A.; Wright, R.; Yuan, V.; Zander, M.E.

    1992-01-01

    This paper describes a video diagnostic system used to measure the beam profile and position of the Ground Test Accelerator 2.5 MeV H - ion beam as it exits the intermediate matching section. Inelastic collisions between H - ions and residual nitrogen in the vacuum chamber cause the nitrogen to fluoresce. The resulting light is captured through transport optics by an intensified CCD camera and is digitized. Real-time beam profile images are displayed and stored for detailed analysis. Analyzed data showing resolutions for both position and profile measurements will also be presented. (Author) 5 refs., 7 figs

  18. Video profile monitor diagnostic system for GTA

    International Nuclear Information System (INIS)

    Sandoval, D.P.; Garcia, R.C.; Gilpatrick, J.D.; Johnson, K.F.; Shinas, M.A.; Wright, R.; Yuan, V.; Zander, M.E.

    1992-01-01

    This paper describes a video diagnostic system used to measure the beam profile and position of the Ground Test Accelerator 2.5-MeV H - ion beam as it exits the intermediate matching section. Inelastic collisions between H-ions and residual nitrogen to fluoresce. The resulting light is captured through transport optics by an intensified CCD camera and is digitized. Real-time beam-profile images are displayed and stored for detailed analysis. Analyzed data showing resolutions for both position and profile measurements will also be presented

  19. Clinical cone beam computed tomography compared to high-resolution peripheral computed tomography in the assessment of distal radius bone.

    Science.gov (United States)

    de Charry, C; Boutroy, S; Ellouz, R; Duboeuf, F; Chapurlat, R; Follet, H; Pialat, J B

    2016-10-01

    Clinical cone beam computed tomography (CBCT) was compared to high-resolution peripheral quantitative computed tomography (HR-pQCT) for the assessment of ex vivo radii. Strong correlations were found for geometry, volumetric density, and trabecular structure. Using CBCT, bone architecture assessment was feasible but compared to HR-pQCT, trabecular parameters were overestimated whereas cortical ones were underestimated. HR-pQCT is the most widely used technique to assess bone microarchitecture in vivo. Yet, this technology has been only applicable at peripheral sites, in only few research centers. Clinical CBCT is more widely available but quantitative assessment of the bone structure is usually not performed. We aimed to compare the assessment of bone structure with CBCT (NewTom 5G, QR, Verona, Italy) and HR-pQCT (XtremeCT, Scanco Medical AG, Brüttisellen, Switzerland). Twenty-four distal radius specimens were scanned with these two devices with a reconstructed voxel size of 75 μm for Newtom 5G and 82 μm for XtremeCT, respectively. A rescaling-registration scheme was used to define the common volume of interest. Cortical and trabecular compartments were separated using a semiautomated double contouring method. Density and microstructure were assessed with the HR-pQCT software on both modality images. Strong correlations were found for geometry parameters (r = 0.98-0.99), volumetric density (r = 0.91-0.99), and trabecular structure (r = 0.94-0.99), all p < 0.001. Correlations were lower for cortical microstructure (r = 0.80-0.89), p < 0.001. However, absolute differences were observed between modalities for all parameters, with an overestimation of the trabecular structure (trabecular number, 1.62 ± 0.37 vs. 1.47 ± 0.36 mm(-1)) and an underestimation of the cortical microstructure (cortical porosity, 3.3 ± 1.3 vs. 4.4 ± 1.4 %) assessed on CBCT images compared to HR-pQCT images. Clinical CBCT devices are able to

  20. Linear Energy Transfer-Dependent Change in Rice Gene Expression Profile after Heavy-Ion Beam Irradiation.

    Directory of Open Access Journals (Sweden)

    Kotaro Ishii

    Full Text Available A heavy-ion beam has been recognized as an effective mutagen for plant breeding and applied to the many kinds of crops including rice. In contrast with X-ray or γ-ray, the heavy-ion beam is characterized by a high linear energy transfer (LET. LET is an important factor affecting several aspects of the irradiation effect, e.g. cell survival and mutation frequency, making the heavy-ion beam an effective mutagen. To study the mechanisms behind LET-dependent effects, expression profiling was performed after heavy-ion beam irradiation of imbibed rice seeds. Array-based experiments at three time points (0.5, 1, 2 h after the irradiation revealed that the number of up- or down-regulated genes was highest 2 h after irradiation. Array-based experiments with four different LETs at 2 h after irradiation identified LET-independent regulated genes that were up/down-regulated regardless of the value of LET; LET-dependent regulated genes, whose expression level increased with the rise of LET value, were also identified. Gene ontology (GO analysis of LET-independent up-regulated genes showed that some GO terms were commonly enriched, both 2 hours and 3 weeks after irradiation. GO terms enriched in LET-dependent regulated genes implied that some factor regulates genes that have kinase activity or DNA-binding activity in cooperation with the ATM gene. Of the LET-dependent up-regulated genes, OsPARP3 and OsPCNA were identified, which are involved in DNA repair pathways. This indicates that the Ku-independent alternative non-homologous end-joining pathway may contribute to repairing complex DNA legions induced by high-LET irradiation. These findings may clarify various LET-dependent responses in rice.

  1. Linear Energy Transfer-Dependent Change in Rice Gene Expression Profile after Heavy-Ion Beam Irradiation.

    Science.gov (United States)

    Ishii, Kotaro; Kazama, Yusuke; Morita, Ryouhei; Hirano, Tomonari; Ikeda, Tokihiro; Usuda, Sachiko; Hayashi, Yoriko; Ohbu, Sumie; Motoyama, Ritsuko; Nagamura, Yoshiaki; Abe, Tomoko

    2016-01-01

    A heavy-ion beam has been recognized as an effective mutagen for plant breeding and applied to the many kinds of crops including rice. In contrast with X-ray or γ-ray, the heavy-ion beam is characterized by a high linear energy transfer (LET). LET is an important factor affecting several aspects of the irradiation effect, e.g. cell survival and mutation frequency, making the heavy-ion beam an effective mutagen. To study the mechanisms behind LET-dependent effects, expression profiling was performed after heavy-ion beam irradiation of imbibed rice seeds. Array-based experiments at three time points (0.5, 1, 2 h after the irradiation) revealed that the number of up- or down-regulated genes was highest 2 h after irradiation. Array-based experiments with four different LETs at 2 h after irradiation identified LET-independent regulated genes that were up/down-regulated regardless of the value of LET; LET-dependent regulated genes, whose expression level increased with the rise of LET value, were also identified. Gene ontology (GO) analysis of LET-independent up-regulated genes showed that some GO terms were commonly enriched, both 2 hours and 3 weeks after irradiation. GO terms enriched in LET-dependent regulated genes implied that some factor regulates genes that have kinase activity or DNA-binding activity in cooperation with the ATM gene. Of the LET-dependent up-regulated genes, OsPARP3 and OsPCNA were identified, which are involved in DNA repair pathways. This indicates that the Ku-independent alternative non-homologous end-joining pathway may contribute to repairing complex DNA legions induced by high-LET irradiation. These findings may clarify various LET-dependent responses in rice.

  2. Label-free cellular structure imaging with 82 nm lateral resolution using an electron-beam excitation-assisted optical microscope.

    Science.gov (United States)

    Fukuta, Masahiro; Masuda, Yuriko; Inami, Wataru; Kawata, Yoshimasa

    2016-07-25

    We present label-free and high spatial-resolution imaging for specific cellular structures using an electron-beam excitation-assisted optical microscope (EXA microscope). Images of the actin filament and mitochondria of stained HeLa cells, obtained by fluorescence and EXA microscopy, were compared to identify cellular structures. Based on these results, we demonstrated the feasibility of identifying label-free cellular structures at a spatial resolution of 82 nm. Using numerical analysis, we calculated the imaging depth region and determined the spot size of a cathodoluminescent (CL) light source to be 83 nm at the membrane surface.

  3. Nano and micro structured targets to modulate the spatial profile of laser driven proton beams

    Czech Academy of Sciences Publication Activity Database

    Giuffrida, Lorenzo; Svensson, K.; Pšikal, Jan; Margarone, Daniele; Lutoslawski, P.; Scuderi, Valentina; Milluzzo, G.; Kaufman, Jan; Wiste, Tuomas; Dalui, M.; Ekerfelt, H.; Gallardo Gonzalez, I.; Lundh, O.; Persson, A.; Picciotto, A.; Crivellari, M.; Bagolini, A.; Bellutti, P.; Magnusson, J.; Gonoskov, A.; Klimša, Ladislav; Kopeček, Jaromír; Laštovička, Tomáš; Cirrone, G.A.P.; Wahlström, C.-G.; Korn, Georg

    2017-01-01

    Roč. 12, Mar (2017), s. 1-6, č. článku C03040. ISSN 1748-0221. [Medical and Multidisciplinary Applications of Laser -Driven Ion Beams at Eli-Beamlines. Catania, 07.09.2016-10.09.2016] R&D Projects: GA ČR(CZ) GA15-02964S; GA MŠk EF15_008/0000162 Grant - others:ELI Beamlines(XE) CZ.02.1.01/0.0/0.0/15_008/0000162 Institutional support: RVO:68378271 Keywords : accelerator Applications * Beam dynamics Subject RIV: BH - Optics, Masers, Laser s OBOR OECD: Optics (including laser optics and quantum optics) Impact factor: 1.220, year: 2016

  4. Energy deposition profile for modification proposal of ISOLDE’s HRS Beam Dump, from FLUKA simulations

    CERN Document Server

    Vlachoudis, V

    2014-01-01

    The current ISOLDE HRS beam dump has been found to be unsuitable on previous simulations, due to thermomechanical stresses. In this paper a proposal for modifying HRS dump is studied using FLUKA. The energy deposited in this modified beam dump and the amount of neutrons streaming to the tunnel area are scored and compared with the simulation of current dump. Two versions of the modification have been assessed, determining which of them is more desirable in terms of influence of radiation on ISOLDE’s tunnel. Finally, a rough estimate of temperature raise in the modified dump is shown. Further conclusions on the adequacy of these modifications need to include the thermomechanical calculations’ results, based on those presented here.

  5. Calibration of the OHREX high-resolution imaging crystal spectrometer at the Livermore electron beam ion traps

    Energy Technology Data Exchange (ETDEWEB)

    Hell, N. [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); Dr. Remeis-Sternwarte and ECAP, Universität Erlangen-Nürnberg, Bamberg 96049 (Germany); Beiersdorfer, P.; Magee, E. W.; Brown, G. V. [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States)

    2016-11-15

    We report the calibration of the Orion High-Resolution X-ray (OHREX) imaging crystal spectrometer at the EBIT-I electron beam ion trap at Livermore. Two such instruments, dubbed OHREX-1 and OHREX-2, are fielded for plasma diagnostics at the Orion laser facility in the United Kingdom. The OHREX spectrometer can simultaneously house two spherically bent crystals with a radius of curvature of r = 67.2 cm. The focusing properties of the spectrometer allow both for larger distance to the source due to the increase in collected light and for observation of extended sources. OHREX is designed to cover a 2.5°–3° spectral range at Bragg angles around 51.3°. The typically high resolving powers at these large Bragg angles are ideally suited for line shape diagnostics. For instance, the nominal resolving power of the instrument (>10 000) is much higher than the effective resolving power associated with the Doppler broadening due to the temperature of the trapped ions in EBIT-I. The effective resolving power is only around 3000 at typical EBIT-I conditions, which nevertheless is sufficient to set up and test the instrument’s spectral characteristics. We have calibrated the spectral range for a number of crystals using well known reference lines in the first and second order and derived the ion temperatures from these lines. We have also made use of the 50 μm size of the EBIT-I source width to characterize the spatial focusing of the spectrometer.

  6. Spatial resolution measurements by Radia diagnostic software with SEDENTEXCT image quality phantom in cone beam CT for dental use.

    Science.gov (United States)

    Watanabe, Hiroshi; Nomura, Yoshikazu; Kuribayashi, Ami; Kurabayashi, Tohru

    2018-02-01

    We aimed to employ the Radia diagnostic software with the safety and efficacy of a new emerging dental X-ray modality (SEDENTEXCT) image quality (IQ) phantom in CT, and to evaluate its validity. The SEDENTEXCT IQ phantom and Radia diagnostic software were employed. The phantom was scanned using one medical full-body CT and two dentomaxillofacial cone beam CTs. The obtained images were imported to the Radia software, and the spatial resolution outputs were evaluated. The oversampling method was employed using our original wire phantom as a reference. The resultant modulation transfer function (MTF) curves were compared. The null hypothesis was that MTF curves generated using both methods would be in agreement. One-way analysis of variance tests were applied to the f50 and f10 values from the MTF curves. The f10 values were subjectively confirmed by observing the line pair modules. The Radia software reported the MTF curves on the xy-plane of the CT scans, but could not return f50 and f10 values on the z-axis. The null hypothesis concerning the reported MTF curves on the xy-plane was rejected. There were significant differences between the results of the Radia software and our reference method, except for f10 values in CS9300. These findings were consistent with our line pair observations. We evaluated the validity of the Radia software with the SEDENTEXCT IQ phantom. The data provided were semi-automatic, albeit with problems and statistically different from our reference. We hope the manufacturer will overcome these limitations.

  7. An integrated strategy for in vivo metabolite profiling using high-resolution mass spectrometry based data processing techniques

    International Nuclear Information System (INIS)

    Guo, Jian; Zhang, Minli; Elmore, Charles S.; Vishwanathan, Karthick

    2013-01-01

    Graphical abstract: -- Highlights: •Profiling the metabolites of model compounds in rats using high resolution mass spectrometry based data processing techniques. •Demonstrating an integrated strategy in vivo metabolite profiling using data mining tools. •Unusual metabolites generated via thiazole-ring opening were characterized based on processed LC–MS.data. -- Abstract: An ongoing challenge of drug metabolite profiling is to detect and identify unknown or low-level metabolites in complex biological matrices. Here we present a generic strategy for metabolite detection using multiple accurate-mass-based data processing tools via the analysis of rat samples of two model drug candidates, AZD6280 and AZ12488024. First, the function of isotopic pattern recognition was proved to be highly effective in the detection of metabolites derived from [ 14 C]-AZD6280 that possesses a distinct isotopic pattern. The metabolites revealed using this approach were in excellent qualitative correlation to those observed in radiochromatograms. Second, the effectiveness of accurate mass based untargeted data mining tools such as background subtraction, mass defect filtering, or a data mining package (MZmine) used for metabolomic analysis in detection of metabolites of [ 14 C]-AZ12488024 in rat urine, feces, bile and plasma samples was examined and a total of 33 metabolites of AZ12488024 were detected. Among them, at least 16 metabolites were only detected by the aid of the data mining packages and not via radiochromatograms. New metabolic pathways such as S-oxidation and thiomethylation reactions occurring on the thiazole ring were proposed based on the processed data. The results of these experiments also demonstrated that accurate mass-based mass defect filtering (MDF) and data mining techniques used in metabolomics are complementary and can be valuable tools for delineating low-level metabolites in complex matrices. Furthermore, the application of distinct multiple data

  8. Laser-driven high-energy proton beam with homogeneous spatial profile from a nanosphere target

    Czech Academy of Sciences Publication Activity Database

    Bulanov, S.S.; Esarey, E.; Schroeder, C.B.; Leemans, W.P.; Bulanov, S.V.; Margarone, Daniele; Korn, Georg; Haberer, T.

    2015-01-01

    Roč. 18, č. 6 (2015), "061302-1"-"061302-6" ISSN 1098-4402 R&D Projects: GA MŠk ED1.1.00/02.0061 Grant - others:ELI Beamlines(XE) CZ.1.05/1.1.00/02.0061 Institutional support: RVO:68378271 Keywords : ion accelerators * tumor-therapy * proton * beams * plasmas Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.500, year: 2015

  9. High-Resolution Replication Profiles Define the Stochastic Nature of Genome Replication Initiation and Termination

    Directory of Open Access Journals (Sweden)

    Michelle Hawkins

    2013-11-01

    Full Text Available Eukaryotic genome replication is stochastic, and each cell uses a different cohort of replication origins. We demonstrate that interpreting high-resolution Saccharomyces cerevisiae genome replication data with a mathematical model allows quantification of the stochastic nature of genome replication, including the efficiency of each origin and the distribution of termination events. Single-cell measurements support the inferred values for stochastic origin activation time. A strain, in which three origins were inactivated, confirmed that the distribution of termination events is primarily dictated by the stochastic activation time of origins. Cell-to-cell variability in origin activity ensures that termination events are widely distributed across virtually the whole genome. We propose that the heterogeneity in origin usage contributes to genome stability by limiting potentially deleterious events from accumulating at particular loci.

  10. Technical aspects of X-ray micro-computed tomography. Initial experience of 27-μm resolution using feldkamp cone-beam reconstruction

    International Nuclear Information System (INIS)

    Yamamoto, Shuji; Suzuki, Masahiro; Kohara, Kazushi; Iinuma, Gen; Moriyama, Noriyuki

    2007-01-01

    The objective of this study was to introduce the technical utility of micro-computed tomography (CT) with 27-μm resolution by cone-beam CT algorithm. Whole-body micro-CT scans were performed to honeybee. Two- and three-dimensional image analyses were performed by originally developed and available open-source software for acquired images. The original contribution of this work is to describe the technical characteristics of the X-ray micro-CT system, keeping a small experimental insect in a unique condition. Micro-CT may be used as a rapid prototyping tool to research and understand the high-resolution system with Feldkamp cone-beam reconstruction. (author)

  11. Precision and resolution on Tore-Supra ECE electron temperature profile measurements

    International Nuclear Information System (INIS)

    Segui, J.L.; Molina, D.; Goniche, M.

    2003-01-01

    A 16-channel heterodyne radiometer, 2 GHz spaced, is used on Tore-Supra to measure the electron cyclotron emission in the frequency range 78-110 GHz for the O mode and 94 -126 GHz for the X mode. In the equatorial plane, a dual polarisation Gaussian optics lens antenna, with a perpendicular line of sight (with respect to the magnetic field), gives ECE measurements with very low refraction and Doppler effects. A separate O/X mode RF front-end allows the use of an IF electronic mode selector. This improves time stability calibration and gives the potentiality of simultaneous O/X mode measurements in the 94 -110 GHz RF band for polarisation studies. RF and IF filters reject the gyrotron frequency (118 GHz) in order to perform temperature measurements during ECRH plasmas. A precise absolute spectral calibration is performed outside the vacuum vessel by using a 600 deg. C black body, a digital signal averaging on the waveform generated by a mechanical chopper placed directly in front of it, and a simulation window without Fabry-Perot effects. The calibration precision leads to ECE temperature profiles which are very consistent with Thomson scattering measurements and guarantees a good stability of the ECE profiles for small changes on the magnetic field (absolute precision ± 6%, relative precision between channels ± 3%). Post-pulse data processing takes routinely into account the total magnetic field (B vacuum with ripple, B para , B dia , B pol , all with analytical formulations), the radial relativistic shift (analytical formulation is used), the refraction, not described in this paper, (cut-off detection with safety margin to avoid strong refraction), the nonthermal ECE spectra, not described in this paper, during LHCD (using an electron density threshold criterion). These previous analytical formulations are compatible with real time processing. Relativistic radial broadening simulations show that it is useful to fulfill 32 channels (1 GHz spaced). (authors)

  12. Precision and resolution on Tore-Supra ECE electron temperature profile measurements

    Energy Technology Data Exchange (ETDEWEB)

    Segui, J.L.; Molina, D.; Goniche, M. [Association EURATOM -CEA, CEA/DSM/DRFC CEA-Cadarache, 13108 St Paul-lez-Durance (France)

    2003-07-01

    A 16-channel heterodyne radiometer, 2 GHz spaced, is used on Tore-Supra to measure the electron cyclotron emission in the frequency range 78-110 GHz for the O mode and 94 -126 GHz for the X mode. In the equatorial plane, a dual polarisation Gaussian optics lens antenna, with a perpendicular line of sight (with respect to the magnetic field), gives ECE measurements with very low refraction and Doppler effects. A separate O/X mode RF front-end allows the use of an IF electronic mode selector. This improves time stability calibration and gives the potentiality of simultaneous O/X mode measurements in the 94 -110 GHz RF band for polarisation studies. RF and IF filters reject the gyrotron frequency (118 GHz) in order to perform temperature measurements during ECRH plasmas. A precise absolute spectral calibration is performed outside the vacuum vessel by using a 600 deg. C black body, a digital signal averaging on the waveform generated by a mechanical chopper placed directly in front of it, and a simulation window without Fabry-Perot effects. The calibration precision leads to ECE temperature profiles which are very consistent with Thomson scattering measurements and guarantees a good stability of the ECE profiles for small changes on the magnetic field (absolute precision {+-} 6%, relative precision between channels {+-} 3%). Post-pulse data processing takes routinely into account the total magnetic field (B{sub vacuum} with ripple, B{sub para}, B{sub dia}, B{sub pol}, all with analytical formulations), the radial relativistic shift (analytical formulation is used), the refraction, not described in this paper, (cut-off detection with safety margin to avoid strong refraction), the nonthermal ECE spectra, not described in this paper, during LHCD (using an electron density threshold criterion). These previous analytical formulations are compatible with real time processing. Relativistic radial broadening simulations show that it is useful to fulfill 32 channels (1 GHz

  13. High-resolution He beam scattering as a tool for the investigation of the structural and dynamical properties of surface soliton dislocations

    International Nuclear Information System (INIS)

    El-Batanouny, M.; Martini, K.M.

    1986-01-01

    We discuss the applicability of high-resolution-He-beam/surface scattering to the investigation of the structural and dynamic properties of soliton-like surface misfit dislocations and associated phase transitions. We present evidence, based on recent He diffraction measurements, for the existence of double-sine-Gordon soliton-like dislocations on the reconstructed Au(111) surface. 18 refs., 3 figs., 1 tab

  14. Effects of thermal conduction and convection on temperature profile in a water calorimeter for proton beams

    Energy Technology Data Exchange (ETDEWEB)

    Gargioni, E; Manfredotti, C [Torino Univ. (Italy). Dipt. di Fisica; Laitano, R F; Guerra, A S [Ist. Nazionale di Metrologia delle Radiazioni Ionizzanti, ENEA, Roma (Italy)

    1997-09-01

    In water calorimetry, in addition to the temperature increase due to beam energy deposition in water, unwanted thermal effects occur during and after calorimeter irradiation. This should be accounted for by applying proper corrections to the experimental results. In order to determine such corrections heat flow calculations were performed using the `finite element` method. This method applies even to complex 3D geometries with not necessarily symmetric conditions. Some preliminary results of these calculations are presented together with a description of the analytical method for the evaluation of the correction factors that should be applied to the experimental results to account for the above thermal effects. (orig.)

  15. High resolution resistivity profiling using STRATAGEM system; Stratagem wo mochiita kobunkainohi teiko kozo tansarei

    Energy Technology Data Exchange (ETDEWEB)

    Yamane, K; Inoue, J; Takasugi, S [GERD Geothermal Energy Research and Development Co. Ltd., Tokyo (Japan); Inazaki, T [Public Works Research Institute, Tsukuba (Japan)

    1997-05-27

    A tensor type CSMT method (STRATAGEM) was introduced for the purpose of investigating shallow subsurface, and a field test has been carried out thereon. This system consists of a transmission section, and a sensor section and a data acquisition and processing section to observe waveforms in a responsive electromagnetic field. The signal source is a semi-circular air loop with a radius of a little smaller than 2 m. The measuring points were selected at locations about 200 m apart from the signal source to measure two electric field components and two magnetic field components by using sensors installed on the ground surface. The field test was performed at the Yutsubo area in Oita Prefecture, Japan. The electric field dipole is basically 5 m long, while S and E lines are 10 m long. The measurement frequency ranges from 96 kHz to 1000 kHz. The measurement time was about five minutes, and the whole measurement work including apparatus set-up and withdrawal was completed in about 15 minutes to minimize interference with the field which is a meadow. The field test result revealed that resistivity profile in shallow subsurface can be obtained much more easily than with the conventional CSMT method. 2 refs., 10 figs.

  16. Use of a standard set of profiles of open fields for photon beams in hand-held calculator (tele)

    International Nuclear Information System (INIS)

    Perez Guevara, Adrian; Rodriguez Zayas, Michael; Reyes Gonzalez, Tommy; Gonzalez Perez, Yelina; Sola Rodriguez, Yeline; Sanchez Zamora, Luis; Caballero, Roberto

    2009-01-01

    Clinical Dosimetry has gone through different stages in their evolution to our days advanced computer programs for treatment planning show the 3D dose distribution, complex algorithms for calculating 3D dose, complex treatment techniques, etc. All this has made the verification field treatment time or dose given to the PTV using calculations manuals are increasingly uncertain, reaching values that can exceed ±10%. It is proposed a calculation tool that uses EXCEL parameters obtained by fitting model profiles open fields. This calculator (TELE) taking information from the fields of PTV and treatments patient anatomical data allows verification of the dose contributions any point, correction of surface heterogeneity of the tissues present in the beam to the point of calculation. (Author)

  17. Ion-beam-induced topography and compositional changes in depth profiling

    International Nuclear Information System (INIS)

    Carter, G.; Nobes, M.J.

    1992-01-01

    When energetic ions penetrate and stop in solids they not only add a new atomic constituent to the matrix but they also create atomic recoils and defects. The fluxes of these entities can give rise to spatial redistribution of atomic components, which may be partly or completely balanced by reordering and relaxation processes. These latter, in turn, may be influenced by fields and gradients induced by the primary relocation processes and by the energy deposited. These will include quasi-thermal, concentration (or chemical potential) and electrostatic gradients and may act to enhance or suppress atomic redistribution. Some, or all, of these processes will operate, depending upon the system under study, when energetic ions are employed to sputter erode a substrate for depth sectioning and, quite generally, can perturb the atomic depth profile that it is intended to evaluate. Theoretical and computational approaches to modelling such processes will be outlined and experimental examples shown which illustrate specific phenomena. In particular the accumulation of implant species and defect generation or redistribution can modify, with increasing ion fluence, the local sputtering mechanism and create further problems in depth profile analysis as a changing surface topography penetrates the solid. Examples of such topographic evolution and its influence on depth profiling analysis will be given and models to explain general and specific behaviour will be outlined. The commonality of models which examine both depth-dependent composition modification and surface topography evolution will be stressed. (author)

  18. Shave-off depth profiling: Depth profiling with an absolute depth scale

    International Nuclear Information System (INIS)

    Nojima, M.; Maekawa, A.; Yamamoto, T.; Tomiyasu, B.; Sakamoto, T.; Owari, M.; Nihei, Y.

    2006-01-01

    Shave-off depth profiling provides profiling with an absolute depth scale. This method uses a focused ion beam (FIB) micro-machining process to provide the depth profile. We show that the shave-off depth profile of a particle reflected the spherical shape of the sample and signal intensities had no relationship to the depth. Through the introduction of FIB micro-sampling, the shave-off depth profiling of a dynamic random access memory (DRAM) tip was carried out. The shave-off profile agreed with a blue print from the manufacturing process. Finally, shave-off depth profiling is discussed with respect to resolutions and future directions

  19. A comparative study for spatial resolution and subjective image characteristics of a multi-slice CT and a cone-beam CT for dental use

    International Nuclear Information System (INIS)

    Watanabe, Hiroshi; Honda, Eiichi; Tetsumura, Akemi; Kurabayashi, Tohru

    2011-01-01

    Purpose: Multi-slice CT (MSCT) and cone-beam CT (CBCT) are widely used in dental practice. This study compared the spatial resolution of these CT systems to elucidate which CT modalities should be selected for various clinical cases. Materials and methods: As MSCT and CBCT apparatuses, Somatom Sensation 64 and 3D Accuitomo instruments, respectively, were used. As an objective evaluation of spatial resolution of these CT systems, modulation transfer function (MTF) analysis was performed employing an over-sampling method. The results of MTF analysis were confirmed with a line-pair test using CATPHAN. As a subjective evaluation, a microstructure visualization ability study was performed using a Jcl:SD rat and a head CT phantom. Results: MTF analysis showed that for the in-plane direction, the z-axis ultrahigh resolution mode (zUHR) of the Sensation 64 and 3D Accuitomo instruments had higher spatial resolutions than the conventional mode (64x) of the Sensation 64, but for the longitudinal direction, the 3D Accuitomo had clearly higher spatial resolution than either mode of the Sensation 64. A line-pair test study and microstructure visualization ability studies confirmed the results for MTF analysis. However, images of the rat and the CT phantom revealed that the 3D Accuitomo demonstrated the failure to visualize the soft tissues along with aliasing and beam-hardening artifacts, which were not observed in the Sensation 64. Conclusions: This study successfully applied spatial resolution analysis using MSCT and CBCT systems in a comparative manner. These findings could help in deciding which CT modality should be selected for various clinical cases.

  20. Modeling and evaluation of a high-resolution CMOS detector for cone-beam CT of the extremities.

    Science.gov (United States)

    Cao, Qian; Sisniega, Alejandro; Brehler, Michael; Stayman, J Webster; Yorkston, John; Siewerdsen, Jeffrey H; Zbijewski, Wojciech

    2018-01-01

    Quantitative assessment of trabecular bone microarchitecture in extremity cone-beam CT (CBCT) would benefit from the high spatial resolution, low electronic noise, and fast scan time provided by complementary metal-oxide semiconductor (CMOS) x-ray detectors. We investigate the performance of CMOS sensors in extremity CBCT, in particular with respect to potential advantages of thin (CMOS x-ray detector incorporating the effects of CsI:Tl scintillator thickness was developed. Simulation studies were performed using nominal extremity CBCT acquisition protocols (90 kVp, 0.126 mAs/projection). A range of scintillator thickness (0.35-0.75 mm), pixel size (0.05-0.4 mm), focal spot size (0.05-0.7 mm), magnification (1.1-2.1), and dose (15-40 mGy) was considered. The detectability index was evaluated for both CMOS and a-Si:H flat-panel detector (FPD) configurations for a range of imaging tasks emphasizing spatial frequencies associated with feature size aobj. Experimental validation was performed on a CBCT test bench in the geometry of a compact orthopedic CBCT system (SAD = 43.1 cm, SDD = 56.0 cm, matching that of the Carestream OnSight 3D system). The test-bench studies involved a 0.3 mm focal spot x-ray source and two CMOS detectors (Dalsa Xineos-3030HR, 0.099 mm pixel pitch) - one with the standard CsI:Tl thickness of 0.7 mm (C700) and one with a custom 0.4 mm thick scintillator (C400). Measurements of modulation transfer function (MTF), detective quantum efficiency (DQE), and CBCT scans of a cadaveric knee (15 mGy) were obtained for each detector. Optimal detectability for high-frequency tasks (feature size of ~0.06 mm, consistent with the size of trabeculae) was ~4× for the C700 CMOS detector compared to the a-Si:H FPD at nominal system geometry of extremity CBCT. This is due to ~5× lower electronic noise of a CMOS sensor, which enables input quantum-limited imaging at smaller pixel size. Optimal pixel size for high-frequency tasks was CMOS

  1. Nano and micro structured targets to modulate the spatial profile of laser driven proton beams

    Czech Academy of Sciences Publication Activity Database

    Giuffrida, Lorenzo; Svensson, K.; Pšikal, Jan; Margarone, Daniele; Lutoslawski, P.; Scuderi, Valentina; Milluzzo, G.; Kaufman, Jan; Wiste, Tuomas; Dalui, M.; Ekerfelt, H.; Gonzalez, I.G.; Lundh, O.; Persson, A.; Picciotto, A.; Crivellari, M.; Bagolini, A.; Bellutti, P.; Magnusson, J.; Gonoskov, A.; Klimša, Ladislav; Kopeček, Jaromír; Laštovička, Tomáš; Cirrone, G.A.P.; Wahlström, C.-G.; Korn, Georg

    2017-01-01

    Roč. 12, Mar (2017), s. 1-6, č. článku C03040. ISSN 1748-0221 R&D Projects: GA MŠk EF15_008/0000162; GA MŠk LQ1606; GA ČR(CZ) GA15-02964S EU Projects: European Commission(XE) 284464 - LASER LAB-EUROPE Grant - others:ELI Beamlines(XE) CZ.02.1.01/0.0/0.0/15_008/0000162 Institutional support: RVO:68378271 Keywords : accelerator applications * beam dynamics Subject RIV: BL - Plasma and Gas Discharge Physics OBOR OECD: Fluids and plasma physics (including surface physics) Impact factor: 1.220, year: 2016

  2. Z-Slicer: A Scheme for Shaping the Electron Beam Profile in a Linac

    Energy Technology Data Exchange (ETDEWEB)

    Thangaraj, J. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Crawford, D. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Broemmelsiek, D. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Thurman-Keup, R. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Baffes, C. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Wortley, W. [Univ. of Rochester, NY (United States)

    2014-01-01

    A train of short bunches ( 100 fs) are at a premium at accelerator facilities and their applications include terahertz (THz) generation, short bunch diagnostics, advanced accelerator R&D, etc. In this work we report on the design and simulation of an experiment involving a 20 MeV electron beam, that will be intercepted by a set of metallic slits inside a bunch compressor. After the mask, some electrons are scattered while other pass through unaffected. After exiting the bunch compressor, those electrons that were not affected by the slits will appear as short electron bunches. The key advantage of our scheme is its simplicity, tunability and low cost. The scheme does not require any additional hardware such as lasers, undulator, or transverse deflecting cavity. The tuning variable is only the RF-chirp. The detection of the bunching requires just a skew quad in the chicane and a transverse screen downstream.

  3. AGS BOOSTER BEAM POSITION, TUNE, AND LONGITUDINAL PROFILE DATA ACQUISITION SYSTEM

    International Nuclear Information System (INIS)

    BROWN, K.A.; AHRENS, L.; SEVERINO, F; SMITH, K.; WILINSKI, M

    2003-01-01

    In this paper we will describe a data acquisition system designed and developed for the AGS Booster. The system was motivated by the need to get high quality beam diagnostics from the AGS Booster. This was accomplished by locating the electronics and digital data acquisition close to the Booster ring, to minimize loss of bandwidth in the original signals. In addition we had to develop the system rapidly and at a low cost. The system consists of a Lecroy digital oscilloscope which is interfaced through a National Instruments LabView(trademark) server application, developed for this project. This allows multiple client applications to time share the scope without interfering with each other. We will present a description of the system design along with example clients that we have implemented

  4. Advancing understanding of the fluvial export of organic matter through high-resolution profiling of dissolved organic carbon.

    Science.gov (United States)

    Waldron, S.; Drew, S.; Gilvear, D.; Murray, H.; Heal, K.

    2012-04-01

    Quantifying the natural variation (complexity) of a system remains an enduring scientific challenge in better understanding controls on surface water quality. This characterisation is needed in order to reveal controlling processes, such as dilution, and also to identify unusual load profiles. In trying to capture that natural variation we still rely largely on concentration time series (and associated export budgets) generated from manual spot sampling, or from samples collected by autosamplers - approaches which are unlikely to provide the high temporal resolution of parameter concentration required. Now however, advances in sensor technology are helping us address this challenge. Here we present detailed dissolved organic carbon (DOC) export profiles from a small upland river (9.4 km sq.), generated since June 2011 by semi-continuous logging of UV-vis absorption (200-750 nm, every 2.5 nm) every 30 minutes. Observed increases in the concentration of the DOC, [DOC], in freshwaters have prompted significant research to understand the cause and consequences of increased export: higher levels of DOC require additional water purification of potable sources; increased aquatic export may represent a reduction in terrestrial C-soil sequestration; changes in light penetration can affect the heterotrophic / autotrophic balance in surface waters and this has consequences for the food web structure; increased aquatic export may also result in increased carbon dioxide evasion. Additionally, C export is often linked to nutrient export: we have observed statistically significant stoichiometric relationships between DOC and soluble reactive phosphorus (SRP) concentrations, thus understanding better this parameters offers insight into export of other nutrient and the source of material from which these dissolved compounds are produced; this may be particulate. Our Scottish study site is interesting because there are multiple processes that can contribute to DOC and other nutrient

  5. Relativistic self-focusing of ultra-high intensity X-ray laser beams in warm quantum plasma with upward density profile

    International Nuclear Information System (INIS)

    Habibi, M.; Ghamari, F.

    2014-01-01

    The results of a numerical study of high-intensity X-ray laser beam interaction with warm quantum plasma (WQP) are presented. By means of an upward ramp density profile combined with quantum factors specially the Fermi velocity, we have demonstrated significant relativistic self-focusing (RSF) of a Gaussian electromagnetic beam in the WQP where the Fermi temperature term in the dielectric function is important. For this purpose, we have considered the quantum hydrodynamics model that modifies refractive index of inhomogeneous WQPs with the inclusion of quantum correction through the quantum statistical and diffraction effects in the relativistic regime. Also, to better illustration of the physical difference between warm and cold quantum plasmas and their effect on the RSF, we have derived the envelope equation governing the spot size of X-ray laser beam in Q-plasmas. In addition to the upward ramp density profile, we have found that the quantum effects would be caused much higher oscillation and better focusing of X-ray laser beam in the WQP compared to that of cold quantum case. Our computational results reveal the importance of the use of electrons density profile and Fermi speed in enhancing self-focusing of laser beam

  6. Image reconstruction with shift-variant filtration and its implication for noise and resolution properties in fan-beam computed tomography

    International Nuclear Information System (INIS)

    Pan Xiaochuan; Yu Lifeng

    2003-01-01

    In computed tomography (CT), the fan-beam filtered backprojection (FFBP) algorithm is used widely for image reconstruction. It is known that the FFBP algorithm can significantly amplify data noise and aliasing artifacts in situations where the focal lengths are comparable to or smaller than the size of the field of measurement (FOM). In this work, we propose an algorithm that is less susceptible to data noise, aliasing, and other data inconsistencies than is the FFBP algorithm while retaining the favorable resolution properties of the FFBP algorithm. In an attempt to evaluate the noise properties in reconstructed images, we derive analytic expressions for image variances obtained by use of the FFBP algorithm and the proposed algorithm. Computer simulation studies are conducted for quantitative evaluation of the spatial resolution and noise properties of images reconstructed by use of the algorithms. Numerical results of these studies confirm the favorable spatial resolution and noise properties of the proposed algorithm and verify the validity of the theoretically predicted image variances. The proposed algorithm and the derived analytic expressions for image variances can have practical implications for both estimation and detection/classification tasks making use of CT images, and they can readily be generalized to other fan-beam geometries

  7. High-resolution mutational profiling suggests the genetic validity of glioblastoma patient-derived pre-clinical models.

    Directory of Open Access Journals (Sweden)

    Shawn E Yost

    Full Text Available Recent advances in the ability to efficiently characterize tumor genomes is enabling targeted drug development, which requires rigorous biomarker-based patient selection to increase effectiveness. Consequently, representative DNA biomarkers become equally important in pre-clinical studies. However, it is still unclear how well these markers are maintained between the primary tumor and the patient-derived tumor models. Here, we report the comprehensive identification of somatic coding mutations and copy number aberrations in four glioblastoma (GBM primary tumors and their matched pre-clinical models: serum-free neurospheres, adherent cell cultures, and mouse xenografts. We developed innovative methods to improve the data quality and allow a strict comparison of matched tumor samples. Our analysis identifies known GBM mutations altering PTEN and TP53 genes, and new actionable mutations such as the loss of PIK3R1, and reveals clear patient-to-patient differences. In contrast, for each patient, we do not observe any significant remodeling of the mutational profile between primary to model tumors and the few discrepancies can be attributed to stochastic errors or differences in sample purity. Similarly, we observe ∼96% primary-to-model concordance in copy number calls in the high-cellularity samples. In contrast to previous reports based on gene expression profiles, we do not observe significant differences at the DNA level between in vitro compared to in vivo models. This study suggests, at a remarkable resolution, the genome-wide conservation of a patient's tumor genetics in various pre-clinical models, and therefore supports their use for the development and testing of personalized targeted therapies.

  8. Screening halogenated environmental contaminants in biota based on isotopic pattern and mass defect provided by high resolution mass spectrometry profiling

    Energy Technology Data Exchange (ETDEWEB)

    Cariou, Ronan, E-mail: laberca@oniris-nantes.fr; Omer, Elsa; Léon, Alexis; Dervilly-Pinel, Gaud; Le Bizec, Bruno

    2016-09-14

    In the present work, we addressed the question of global seeking/screening organohalogenated compounds in a large panel of complex biological matrices, with a particular focus on unknown chemicals that may be considered as potential emerging hazards. A fishing strategy was developed based on untargeted profiling among full scan acquisition datasets provided by high resolution mass spectrometry. Since large datasets arise from such profiling, filtering useful information stands as a central question. In this way, we took advantage of the exact mass differences between Cl and Br isotopes. Indeed, our workflow involved an innovative Visual Basic for Applications script aiming at pairing features according to this mass difference, in order to point out potential organohalogenated clusters, preceded by an automated peak picking step based on the centWave function (xcms package of open access R programming environment). Then, H/Cl-scale mass defect plots were used to visualize the datasets before and after filtering. The filtering script was successfully applied to a dataset generated upon liquid chromatography coupled to ESI(−)-HRMS measurement from one eel muscle extract, allowing for realistic manual investigations of filtered clusters. Starting from 9789 initial obtained features, 1994 features were paired in 589 clusters. Hexabromocyclododecane, chlorinated paraffin series and various other compounds have been identified or tentatively identified, allowing thus broad screening of organohalogenated compounds in this extract. Although realistic, manual review of paired clusters remains time consuming and much effort should be devoted to automation. - Highlights: • We address the screening of halogenated compounds in large Full Scan HRMS datasets. • The workflow involves peak picking, pairing script and review of paired features. • The pairing script is based on exact mass differences between Cl and Br isotopes. • H/Cl scale mass defect plots are used to

  9. Rapid and inexpensive body fluid identification by RNA profiling-based multiplex High Resolution Melt (HRM) analysis.

    Science.gov (United States)

    Hanson, Erin K; Ballantyne, Jack

    2013-01-01

    Positive identification of the nature of biological material present on evidentiary items can be crucial for understanding the circumstances surrounding a crime. However, traditional protein-based methods do not permit the identification of all body fluids and tissues, and thus molecular based strategies for the conclusive identification of all forensically relevant biological fluids and tissues need to be developed. Messenger RNA (mRNA) profiling is an example of such a molecular-based approach. Current mRNA body fluid identification assays involve capillary electrophoresis (CE) or quantitative RT-PCR (qRT-PCR) platforms, each with its own limitations. Both platforms require the use of expensive fluorescently labeled primers or probes. CE-based assays require separate amplification and detection steps thus increasing the analysis time. For qRT-PCR assays, only 3-4 markers can be included in a single reaction since each requires a different fluorescent dye. To simplify mRNA profiling assays, and reduce the time and cost of analysis, we have developed single- and multiplex body fluid High Resolution Melt (HRM) assays for the identification of common forensically relevant biological fluids and tissues. The incorporated biomarkers include IL19 (vaginal secretions), IL1F7 (skin), ALAS2 (blood), MMP10 (menstrual blood), HTN3 (saliva) and TGM4 (semen).  The HRM assays require only unlabeled PCR primers and a single saturating intercalating fluorescent dye (Eva Green). Each body-fluid-specific marker can easily be identified by the presence of a distinct melt peak. Usually, HRM assays are used to detect variants or isoforms for a single gene target. However, we have uniquely developed duplex and triplex HRM assays to permit the simultaneous detection of multiple targets per reaction. Here we describe the development and initial performance evaluation of the developed HRM assays. The results demonstrate the potential use of HRM assays for rapid, and relatively inexpensive

  10. Screening halogenated environmental contaminants in biota based on isotopic pattern and mass defect provided by high resolution mass spectrometry profiling

    International Nuclear Information System (INIS)

    Cariou, Ronan; Omer, Elsa; Léon, Alexis; Dervilly-Pinel, Gaud; Le Bizec, Bruno

    2016-01-01

    In the present work, we addressed the question of global seeking/screening organohalogenated compounds in a large panel of complex biological matrices, with a particular focus on unknown chemicals that may be considered as potential emerging hazards. A fishing strategy was developed based on untargeted profiling among full scan acquisition datasets provided by high resolution mass spectrometry. Since large datasets arise from such profiling, filtering useful information stands as a central question. In this way, we took advantage of the exact mass differences between Cl and Br isotopes. Indeed, our workflow involved an innovative Visual Basic for Applications script aiming at pairing features according to this mass difference, in order to point out potential organohalogenated clusters, preceded by an automated peak picking step based on the centWave function (xcms package of open access R programming environment). Then, H/Cl-scale mass defect plots were used to visualize the datasets before and after filtering. The filtering script was successfully applied to a dataset generated upon liquid chromatography coupled to ESI(−)-HRMS measurement from one eel muscle extract, allowing for realistic manual investigations of filtered clusters. Starting from 9789 initial obtained features, 1994 features were paired in 589 clusters. Hexabromocyclododecane, chlorinated paraffin series and various other compounds have been identified or tentatively identified, allowing thus broad screening of organohalogenated compounds in this extract. Although realistic, manual review of paired clusters remains time consuming and much effort should be devoted to automation. - Highlights: • We address the screening of halogenated compounds in large Full Scan HRMS datasets. • The workflow involves peak picking, pairing script and review of paired features. • The pairing script is based on exact mass differences between Cl and Br isotopes. • H/Cl scale mass defect plots are used to

  11. Classification of Ultra-High Resolution Orthophotos Combined with DSM Using a Dual Morphological Top Hat Profile

    Directory of Open Access Journals (Sweden)

    Qian Zhang

    2015-12-01

    Full Text Available New aerial sensors and platforms (e.g., unmanned aerial vehicles (UAVs are capable of providing ultra-high resolution remote sensing data (less than a 30-cm ground sampling distance (GSD. This type of data is an important source for interpreting sub-building level objects; however, it has not yet been explored. The large-scale differences of urban objects, the high spectral variability and the large perspective effect bring difficulties to the design of descriptive features. Therefore, features representing the spatial information of the objects are essential for dealing with the spectral ambiguity. In this paper, we proposed a dual morphology top-hat profile (DMTHP using both morphology reconstruction and erosion with different granularities. Due to the high dimensional feature space, we have proposed an adaptive scale selection procedure to reduce the feature dimension according to the training samples. The DMTHP is extracted from both images and Digital Surface Models (DSM to obtain complimentary information. The random forest classifier is used to classify the features hierarchically. Quantitative experimental results on aerial images with 9-cm and UAV images with 5-cm GSD are performed. Under our experiments, improvements of 10% and 2% in overall accuracy are obtained in comparison with the well-known differential morphological profile (DMP feature, and superior performance is observed over other tested features. Large format data with 20,000 × 20,000 pixels are used to perform a qualitative experiment using the proposed method, which shows its promising potential. The experiments also demonstrate that the DSM information has greatly enhanced the classification accuracy. In the best case in our experiment, it gives rise to a classification accuracy from 63.93% (spectral information only to 94.48% (the proposed method.

  12. The expression profile of phosphatidylinositol in high spatial resolution imaging mass spectrometry as a potential biomarker for prostate cancer.

    Directory of Open Access Journals (Sweden)

    Takayuki Goto

    Full Text Available High-resolution matrix-assisted laser desorption/ionization imaging mass spectrometry (HR-MALDI-IMS is an emerging application for the comprehensive and detailed analysis of the spatial distribution of ionized molecules in situ on tissue slides. HR-MALDI-IMS in negative mode in a mass range of m/z 500-1000 was performed on optimal cutting temperature (OCT compound-embedded human prostate tissue samples obtained from patients with prostate cancer at the time of radical prostatectomy. HR-MALDI-IMS analysis of the 14 samples in the discovery set identified 26 molecules as highly expressed in the prostate. Tandem mass spectrometry (MS/MS showed that these molecules included 14 phosphatidylinositols (PIs, 3 phosphatidylethanolamines (PEs and 3 phosphatidic acids (PAs. Among the PIs, the expression of PI(18:0/18:1, PI(18:0/20:3 and PI(18:0/20:2 were significantly higher in cancer tissue than in benign epithelium. A biomarker algorithm for prostate cancer was formulated by analyzing the expression profiles of PIs in cancer tissue and benign epithelium of the discovery set using orthogonal partial least squares discriminant analysis (OPLS-DA. The sensitivity and specificity of this algorithm for prostate cancer diagnosis in the 24 validation set samples were 87.5 and 91.7%, respectively. In conclusion, HR-MALDI-IMS identified several PIs as being more highly expressed in prostate cancer than benign prostate epithelium. These differences in PI expression profiles may serve as a novel diagnostic tool for prostate cancer.

  13. Design of mirror and monochromator crystals for a high-resolution multiwavelength anomalous diffraction beam line on a bending magnet at the ESRF

    International Nuclear Information System (INIS)

    Roth, M.; Ferrer, J.; Simon, J.; Geissler, E.

    1992-01-01

    High intensity for diffraction experiments with high-energy resolution on an intense x-ray beam, like the bending magnet beam lines at the ESRF, requires a strict control of the curvature of the optical elements placed in the beam for geometrical focusing and for wavelength monochromatization. Unwanted curvatures can come from nonuniform and variable heating of the optical elements produced by the absorption of x rays. To design the CRG/D2AM beam line described in the accompanying paper, some new techniques were developed to control these effects based on geometrical, i.e., topological, considerations. (1) Cooling of the entrance mirror: longitudinal curvature can be strongly reduced by cooling the mirror from the sides (and not from the rear) and only near the reflecting surface (i.e., not over the whole lateral surface). The cooling can be achieved for instance with an isothermal liquid Ga eutectic bath. (2) Cooling of the first single-crystal Si monochromator: because of the size of the crystal, only cooling from the rear is conceivable in this case. It can be shown by calculation that the curvature due to the front-to-rear gradient can be exactly compensated by the thermal expansion of a metallic layer at the rear of the crystal, having a larger expansion coefficient than Si

  14. Profiles

    International Nuclear Information System (INIS)

    2004-01-01

    Profiles is a synthetic overview of more than 100 national energy markets in the world, providing insightful facts and key energy statistics. A Profile is structured around 6 main items and completed by key statistics: Ministries, public agencies, energy policy are concerned; main companies in the oil, gas, electricity and coal sectors, status, shareholders; reserve, production, imports and exports, electricity and refining capacities; deregulation of prices, subsidies, taxes; consumption trends by sector, energy market shares; main energy projects, production and consumption prospects. Statistical Profiles are present in about 3 pages the main data and indicators on oil, gas, coal and electricity. (A.L.B.)

  15. Charge resolution of a Hungarian brand CR-39(MA-ND) detector exposed to a 84Kr beam of energy 0.45A GeV

    International Nuclear Information System (INIS)

    Bhattacharyya, D.P.; Basu, B.; Pal, P.; Mukherjee, S.C.; Ganguly, A.K.; Hunyady, I.

    1990-01-01

    The Hungarian brand CR-39(MA-ND) plastic has been irradiated with a 84 Kr ion beam of energy 0.45A GeV and etched for four different etching times, viz. 4, 6, 8 and 12 h. The estimated charge resolution of a CR-39(MA-ND) detector for registering the nuclei 32 ≤ Z ≤ 36 was found to be 0.18e which is close to our previous observation of the response with a CR-39(DOP) Pershore made plate exposed to a 1.88A GeV 56 Fe beam at the Lawrence Berkeley Laboratory's Bevalac. It was found that the estimated etch rate ratio V T /V G is independent of etching time. The cone length and minor axis of the etch pits has been found to increase with etching time. (orig.)

  16. High-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR: α-glucosidase inhibitors and acetylated ellagic acid rhamnosides from Myrcia palustris DC. (Myrtaceae)

    DEFF Research Database (Denmark)

    Wubshet, Sileshi Gizachew; Moresco, Henrique H.; Tahtah, Yousof

    2015-01-01

    , and therefore improved drug leads or functional foods containing α-glucosidase inhibitors are needed for management of blood glucose. In this study, leaves of Myrcia palustris were investigated by high-resolution α-glucosidase inhibition profiling combined with HPLC–HRMS–SPE–NMR. This led to identification...

  17. n_TOF New target commissioning and beam characterization

    CERN Multimedia

    Igashira, M

    A full characterization of the neutron beam and experimental conditions for measurement with the new spallation target installed at the n_TOF facility is proposed. In a first step, the behavior the target assembly under the proton beam irradiation will be investigated, in order to complete the target commissioning. Subsequently the neutron beam parameters required to analyze the physics measurements, i.e. neutron fluence, beam profile, energy resolution function and beam related backgrounds as a function of the neutron energy, will be determined.

  18. A novel simultaneous photoelastic and two-beam interferometric system: I. Dynamic full-field evaluation of the elasticity modulus profile of polymeric fibres.

    Science.gov (United States)

    Hamza, A A; Sokkar, T Z N; El-Farahaty, K A; Raslan, M I

    2014-06-01

    A novel optical setup for simultaneous capturing of photoelastic and two-beam interference patterns was designed. The designed optical setup was used to simultaneously record two types of patterns. The first pattern is two-beam interference pattern, and the second one is photoelastic interference pattern produced by objects under stress. This simultaneous capturing of the two patterns allowed us to calculate the full-field distribution of the elasticity modulus profile of fibres. A mathematical expression of the profile of the elasticity modulus was derived. This was applied to evaluate the elasticity modulus of anisotropic isotactic polypropylene fibres during stretching processes. The profile of the elasticity modulus was determined for both static and dynamic in situ cases where the propagation of different structural deformations was observed and studied using the designed optical setup. Patterns were given for illustration. © 2014 The Authors Journal of Microscopy © 2014 Royal Microscopical Society.

  19. Shedding light on cell compartmentation in the candidate phylum Poribacteria by high resolution visualisation and transcriptional profiling

    KAUST Repository

    Jahn, Martin T.

    2016-10-31

    Assigning functions to uncultivated environmental microorganisms continues to be a challenging endeavour. Here, we present a new microscopy protocol for fluorescence in situ hybridisation-correlative light and electron microscopy (FISH-CLEM) that enabled, to our knowledge for the first time, the identification of single cells within their complex microenvironment at electron microscopy resolution. Members of the candidate phylum Poribacteria, common and uncultivated symbionts of marine sponges, were used towards this goal. Cellular 3D reconstructions revealed bipolar, spherical granules of low electron density, which likely represent carbon reserves. Poribacterial activity profiles were retrieved from prokaryotic enriched sponge metatranscriptomes using simulation-based optimised mapping. We observed high transcriptional activity for proteins related to bacterial microcompartments (BMC) and we resolved their subcellular localisation by combining FISH-CLEM with immunohistochemistry (IHC) on ultra-thin sponge tissue sections. In terms of functional relevance, we propose that the BMC-A region may be involved in 1,2-propanediol degradation. The FISH-IHC-CLEM approach was proven an effective toolkit to combine -omics approaches with functional studies and it should be widely applicable in environmental microbiology.

  20. Metabolic profile modifications in milk after enrofloxacin administration studied by liquid chromatography coupled with high resolution mass spectrometry.

    Science.gov (United States)

    Junza, A; Saurina, J; Barrón, D; Minguillón, C

    2016-08-19

    High resolution accurate mass spectrometry (HRMS) operating in full scan MS mode was used in the search and identification of metabolites in raw milk from cows medicated with enrofloxacin. Data consisting of m/z features were taken throughout the entire chromatogram of milk samples from medicated animals and were compared with blank samples. Twenty six different compounds were identified. Some of them were attributed to structures related to enrofloxacin while others were dipeptides or tripeptides. Additionally, enrofloxacin was administered in a controlled treatment for three days. Milk was collected daily from the first day of treatment and until four days after in the search for the identified compounds. The obtained data were chemometrically treated by Principal Component Analysis. Samples were classified by this method into three different groups corresponding to days 1-2, day 3 and days 4-7 considering the different concentration profile evolution of metabolites during the days studied. Tentative metabolic pathways were designed to rationalize the presence of the newly identified compounds. Copyright © 2016 Elsevier B.V. All rights reserved.